WorldWideScience

Sample records for antipsychotic-induced sexual dysfunction

  1. Sexual Dysfunction and Infertility

    Science.gov (United States)

    ... Sexual dysfunction is a problem in a person’s sexual desire, arousal, or orgasm. Sexual dysfunction is common. It ... find they have times when they have less sexual desire and satisfaction because of emotional distress or the ...

  2. Sexual Dysfunction in Women

    Science.gov (United States)

    ... also cause sexual dysfunction. You may have less sexual desire during pregnancy, right after childbirth or when you are breastfeeding. After menopause many women feel less sexual desire, have vaginal dryness or have pain during sex ...

  3. Biology of Sexual Dysfunction

    OpenAIRE

    MN, Anil Kumar; Pai, NB; Rao, S.; Rao, TSS; Goyal, N.

    2009-01-01

    Sexual activity is a multifaceted activity, involving complex interactions between the nervous system, the endocrine system, the vascular system and a variety of structures that are instrumental in sexual excitement, intercourse and satisfaction. Sexual function has three components i.e., desire, arousal and orgasm. Many sexual dysfunctions can be categorized according to the phase of sexual response that is affected. In actual clinical practice however, sexual desire, arousal and orgasmic di...

  4. Biology of Sexual Dysfunction

    Directory of Open Access Journals (Sweden)

    Anil Kumar Mysore Nagaraj

    2009-05-01

    Full Text Available Sexual activity is a multifaceted activity, involving complex interactions between the nervous system, the endocrine system, the vascular system and a variety of structures that are instrumental in sexual excitement, intercourse and satisfaction. Sexual function has three components i.e., desire, arousal and orgasm. Many sexual dysfunctions can be categorized according to the phase of sexual response that is affected. In actual clinical practice however, sexual desire, arousal and orgasmic difficulties more often than not coexist, suggesting an integration of phases. Sexual dysfunction can result from a wide variety of psychological and physiological causes including derangements in the levels of sex hormones and neurotrensmitters. This review deals with the biology of different phases of sexual function as well as implications of hormones and neurotransmitters in sexual dysfunction

  5. Sexual dysfunction in diabetes.

    Science.gov (United States)

    Tamás, Várkonyi; Kempler, Peter

    2014-01-01

    We aimed to summarize the etiology, clinical characteristics, diagnosis, and possible treatment options of sexual dysfunction in diabetic patients of both sexes. Details of dysfunction in diabetic women are less conclusive than in men due to the lack of standardized evaluation of sexual function in women. Male sexual dysfunction is a common complication of diabetes, including abnormalities of orgasmic/ejaculatory function and desire/libido in addition to penile erection. The prevalence of erectile dysfunction (ED) among diabetic men varies from 35% to 75%. Diabetes-induced ED has a multifactorial etiology including metabolic, neurologic, vascular, hormonal, and psychological components. ED should be regarded as the first sign of cardiovascular disease because it can be present before development of symptomatic coronary artery disease, as larger coronary vessels better tolerate the same amount of plaque compared to smaller penile arteries. The diagnosis of ED is based on validated questionnaires and determination of functional and organic abnormalities. First-, second- and third-line therapy may be applied. Phosphodiesterase-5 (PDE-5) inhibitor treatment from the first-line options leads to smooth muscle relaxation in the corpus cavernosum and enhancement in blood flow, resulting in erection during sexual stimulus. The use of PDE-5 inhibitors in the presence of oral nitrates is strictly contraindicated in diabetic men, as in nondiabetic subjects. All PDE-5 inhibitors have been evaluated for ED in diabetic patients with convincing efficacy data. Second-line therapy includes intracavernosal, trans- or intraurethral administration of vasoactive drugs or application of a vacuum device. Third-line therapies are the implantation of penile prosthesis and penile revascularization. PMID:25410225

  6. Antipsychotic-induced Hyperprolactinemia

    Directory of Open Access Journals (Sweden)

    Suheyla Dogan Bulut

    2015-06-01

    Full Text Available Prolactin provides the growth of the mammary gland during pregnancy and synthesis and preparation of breast milk for lactation. Antipsychotics and antidepressants that are frequently used in psychiatry, cause hyperprolactinemia. The prevalent opinion is that especially typical antipsychotics increase prolactin levels primarily by blocking D2 receptors in the anterior pituitary. The effects of atypical antipsychotics on hyperprolactinemia vary. Hyperprolactinemia causes galactorrhea, gynecomastia, sexual dysfunction, infertility, acne, hirsutism in women, weight gain, obesity and mood changes in addition to menstrual irregularities such as oligomenorrhea, polymenorrhea and amenorrhea. In the long term, hyperprolactinemia may cause reduction in bone density and osteoporosis. Hyperprolactinemia as a side effect of antipsychotics drugs and its treatment will be reviewed in this article. [Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry 2015; 7(2: 109-124

  7. Client attributions for sexual dysfunction.

    Science.gov (United States)

    Fichten, C S; Spector, I; Libman, E

    1988-01-01

    This investigation examined attributions for sexual dysfunctions made by 63 individuals and 21 of their partners who presented at a sex therapy service for the following problems: erectile dysfunction, premature ejaculation, and female orgasmic dysfunctions. All participants completed measures of marital adjustment, locus of control, depression and a questionnaire which assessed: attributions of responsibility for the sexual problem, perceived control over sexual functioning, distress, effort made to improve the sexual relationship, and expectations about the efficacy of sex therapy for the problem. Results indicate that both identified patients and their partners, regardless of the dysfunction, blamed the sexual problem on the "dysfunctional individual" rather than on the circumstances or the partner. With respect to the partners, husbands of women with orgasmic dysfunction were more likely to blame themselves than the circumstances, while the opposite was true for wives of males with erectile difficulties. Individuals experiencing the dysfunction perceived themselves and their partners as having little, but equal control over the identified patient's sexuality. Correlational analyses indicate that in identified patients, the better the quality of the marital relationship, the greater the self-blame and the lower the partner blame. Those with happy marriages also made greater efforts to improve their sexual relationship and had higher expectations of success with therapy. The implications of the results for research on the role of attributions in sexual dysfunction and for assessment of cognitive factors in sexually dysfunctional individuals and their partners is discussed. PMID:3172253

  8. Sexual dysfunctions and psychoanalysis.

    Science.gov (United States)

    Levine, E M; Ross, N

    1977-06-01

    The authors examine the major factors involved in recent changes in the social standards and attitudes related to homosexuality. The principal influences investigated include the misconstrued emphasis given to the humanist ideology, which properly stresses the dignity of the individual; the social sciences' relativization of the cultural norms defining homosexuality; the influence of the mass media in disseminating these perspectives and thereby tending to create an acceptable image of homosexuality, and the tendency of all these changes to result in a substantial increase in public acceptance and tolerance of homosexuality. The authors suggest that this trend in public opinion has begun to isolate psychoanalytic knowledge, to reduce its status and acceptability among the public, and to replace it with popular views concerning the meaning of sexual dysfunctions. PMID:869030

  9. Antipsychotics and Sexual Dysfunction: Sexual Dysfunction - Part III

    Directory of Open Access Journals (Sweden)

    Anil Kumar Mysore Nagaraj

    2009-11-01

    Full Text Available Satisfying sexual experience is an essential part of a healthy and enjoyable life for most people. Antipsychotic drugs are among the various factors that affect optimal sexual functioning. Both conventional and novel antipsychotics are associated with significant sexual side effects. This review has presented various studies comparing different antipsychotic drugs. Dopamine antagonism, increased serum prolactin, serotonergic, adrenergic and cholinergic mechanisms are all proposed to be the mechanisms for sexual dysfunction. Drug treatment for this has not given satisfactory long-term results. Knowledge of the receptor pharmacology of an individual antipsychotic will help to determine whether it is more or less likely to cause sexual side effects and its management.

  10. Sexual dysfunctions in psoriatic patients

    Directory of Open Access Journals (Sweden)

    Maria Isabela Sarbu

    2015-04-01

    Full Text Available Psoriasis is a chronic, immune-mediated disorder with a worldwide occurrence characterized by well-defined infiltrated erythematous papules and plaques, covered by silvery white or yellowish scales. It is a physically, socially and emotionally invalidating disorder that affects 1-2% of the population. Sexual health is an important part of general health and sexual dysfunctions can negatively affect self-esteem, confidence, interpersonal relationships and the quality of life. Dermatology Life Quality Index (DLQI, Psoriasis Disability Index (PDI and the Impact of Psoriasis on Quality of Life (IPSO questionnaire are all questionnaires used to assess the quality of life of patients with psoriasis and each has one question regarding sexual dysfunction. Several scales were also designed to particularly assess sexual satisfaction in men and women. The aim of this paper is to perform an overview of the existing studies on sexual dysfunction in psoriatic patients.

  11. Psychiatric disorders and sexual dysfunction.

    Science.gov (United States)

    Waldinger, Marcel D

    2015-01-01

    Sexual problems are highly prevalent among patients with psychiatric disorders. They may be caused by the psychopathology of the psychiatric disorder but also by its pharmacotherapy. Both positive symptoms (e.g., psychosis, hallucinations) as well as negative symptoms (e.g., anhedonia) of schizophrenia may negatively interfere with interpersonal and sexual relationships. Atypical antipsychotics have fewer sexual side-effects than the classic antipsychotics. Mood disorders may affect libido, sexual arousal, orgasm, and erectile function. With the exception of bupropion, agomelatine, mirtazapine, vortioxetine, amineptine, and moclobemide, all antidepressants cause sexual side-effects. Selective serotonin reuptake inhibitors (SSRIs) may particularly delay ejaculation and female orgasm, but also can cause decreased libido and erectile difficulties. SSRI-induced sexual side-effects are dose-dependent and reversible. Very rarely, their sexual side-effects persist after SSRI discontinuation. This is often preceded by genital anesthesia. Some personality characteristics are a risk factor for sexual dysfunction. Also patients with eating disorders may suffer from sexual difficulties. So far, research into psychotropic-induced sexual side-effects suffers from substantial methodologic limitations. Patients tend not to talk with their clinician about their sexual life. Psychiatrists and other doctors need to take the initiative to talk about the patient's sexual life in order to become informed about potential medication-induced sexual difficulties. PMID:26003261

  12. Sexual dysfunctions in psoriatic patients

    OpenAIRE

    Maria Isabela Sarbu; Mircea Tampa; Alexandra Elena Sarbu; Simona Roxana Georgescu

    2015-01-01

    Psoriasis is a chronic, immune-mediated disorder with a worldwide occurrence characterized by well-defined infiltrated erythematous papules and plaques, covered by silvery white or yellowish scales. It is a physically, socially and emotionally invalidating disorder that affects 1-2% of the population. Sexual health is an important part of general health and sexual dysfunctions can negatively affect self-esteem, confidence, interpersonal relationships and the quality of life. Dermatology Life...

  13. [Sexual dysfunction among patients with psychiatric disorders].

    Science.gov (United States)

    Soldati, Lorenzo

    2016-03-16

    Scientific literature shows that sexual dysfunction is more common in patients suffering from psychiatric illness as opposed to the general population. It also shows that the prevalence of sexual dysfunction is underestimated by professionals, partly because patients rarely talk spontaneously about their dysfunctions. However, sexual dysfunction has an impact on patients' mental health. Furthermore, some psychotropic medication, antidepressants and antipsychotics in particular, can hinder sexual functioning and induce sexual dysfunction. These harmful effects can, in turn, reduce patients' compliance with their medical treatments. It is therefore important that practitioners take into account their patients' sexual experience. PMID:27149715

  14. Pharmacotherapy of Sexual Dysfunctions : Current Status

    OpenAIRE

    Avasthi, Ajith; Biswas, Parthasarathy

    2004-01-01

    The sexual dysfunctions are one of the most prevalent conditions. Sexual dysfunctions can have profound effect on the psychological well-being of an individual and the psychosexual relationship of a couple. Management of the sexual dysfunction should be preceded by an accurate diagnosis reached after a complete medical and sexual history and physical examination. Current focus of researchers has been on understanding the pathophysiology of erectile dysfunction, premature ejaculation and other...

  15. Sexual dysfunction in Obsessive-Compulsive disorder

    Directory of Open Access Journals (Sweden)

    Firoozeh Raisi

    2015-05-01

    Conclusion: High prevalence of sexual dysfunction in OCD women and significant correlation between male sexual dysfunction and OCD (r= -481.0 between total score of OCI-R with erectile dysfunction and r= -458.0 between total score of OCI-R and sexual satisfaction could confirm a relation between OCD and sexual disorders. So, evaluation of sexual function in all patients with OCD is recommended.

  16. [Female sexual dysfunction: Drug treatment options].

    Science.gov (United States)

    Alcántara Montero, A; Sánchez Carnerero, C I

    2016-01-01

    Many women will likely experience a sexual problem in their lifetime. Female sexual dysfunction is a broad term used to describe 3 categories of disorders of a multifactorial nature. Effective, but limited pharmacotherapeutic options exist to address female sexual dysfunction. The FDA recently approved the first agent for treatment of hypoactive sexual desire disorder in pre-menopausal women. Off-label use of hormonal therapies, particularly oestrogen and testosterone, are the most widely employed for female sexual dysfunction, particularly in post-menopausal women. Other drugs currently under investigation include phosphodiesterase inhibitors and agents that modulate dopamine or melanocortin receptors. PMID:27041639

  17. Multiple sclerosis and sexual dysfunction

    Institute of Scientific and Technical Information of China (English)

    Zhen-Ni Guo; Si-Yuan He; Hong-Liang Zhang; Jiang Wu; Yi Yang

    2012-01-01

    Multiple sclerosis (MS) is a chronic inflammatory demyelinating disorder of the central nervous system characterized by episodic and progressive neurologic dysfunction resulting from inflammatory and autoimmune reactions.The underlying pathogenesis of MS remains largely unclear.However,it is currently accepted as a T cell-mediated autoimmune disease.Among other clinical manifestations,sexual dysfunction (SD) is a painful but still underreported and underdiagnosed symptom of the disorder.SD in MS patients may result from a complex set of conditions and may be associated with multiple anatomic,physiologic,biologic,medical and psychological factors.SD arises primarily from lesions affecting the neural pathways involved in physiologic function.In addition,psychological factors,the side effects of medications and physical symptoms such as fatigue,muscular weakness,menstrual changes,pain and concerns about bladder and bowel incontinence may also be involved.Since MS primarily affects young people,SD secondary to MS may have a great impact on quality of life.Thus,maintaining a healthy sexual life with MS is an important priority.The treatment of SD requires multidisciplinary teamwork and cooperation among specialists,individual patients,partners and the society.

  18. Etiology and Management of Sexual Dysfunction

    Directory of Open Access Journals (Sweden)

    Narendra Kumar Muthugaduru Shivarudrappa

    2009-09-01

    Full Text Available Sexual dysfunction is the impairment or disruption of any of the three phases of normal sexual functioning, including loss of libido, impairment of physiological arousal and loss, delay or alteration of orgasm. Each one of these can be affected by an orchestra of factors like senility, medical and surgical illnesses, medications and drugs of abuse. Non-pharmacological therapy is the main stay in the treatment of sexual dysfunction and drugs are used as adjuncts for a quicker and better result. Management in many of the cases depends on the primary cause. Here is a review of the major etiological factors of sexual dysfunction and its management

  19. Sexual dysfunctions after prostate cancer radiation therapy

    International Nuclear Information System (INIS)

    Sexual dysfunctions are a quality of life main concern following prostate cancer treatment. After both radiotherapy and brachytherapy, sexual function declines progressively, the onset of occurrence of erectile dysfunction being 12-18 months after both treatments. The pathophysiological pathways by which radiotherapy and brachytherapy cause erectile dysfunction are multi-factorial, as patient co-morbidities, arterial damage, exposure of neurovascular bundle to high levels of radiation, and radiation dose received by the corpora cavernosa at the crurae of the penis may be important in the aetiology of erectile dysfunction. Diagnosis and treatment of postradiation sexual dysfunctions must integrate pre-therapeutic evaluation and information to provide to the patient and his partner a multidisciplinary sexual medicine management. (authors)

  20. Sexual Dysfunction Due to Psychotropic Medications.

    Science.gov (United States)

    Clayton, Anita H; Alkis, Andrew R; Parikh, Nishant B; Votta, Jennifer G

    2016-09-01

    Sexual functioning is important to assess in patients with psychiatric illness as both the condition and associated treatment may contribute to sexual dysfunction (SD). Antidepressant medications, mood stabilizers, antipsychotics, and antianxiety agents may be associated with SD related to drug mechanism of action. Sexual adverse effects may be related to genetic risk factors, impact on neurotransmitters and hormones, and psychological elements. Effective strategies to manage medication-induced sexual dysfunction are initial choice of a drug unlikely to cause SD, switching to a different medication, and adding an antidote to reverse SD. Appropriate interventions should be determined on a clinical case-by-case basis. PMID:27514298

  1. Questionnaires for assessment of female sexual dysfunction

    DEFF Research Database (Denmark)

    Giraldi, Annamaria; Rellini, Alessandra; Pfaus, James G;

    2011-01-01

    There are many methods to evaluate female sexual function and dysfunction (FSD) in clinical and research settings, including questionnaires, structured interviews, and detailed case histories. Of these, questionnaires have become an easy first choice to screen individuals into different categories...

  2. Male Pseudoheterosexuality and Minimal Sexual Dysfunction

    Science.gov (United States)

    Gutstadt, Joseph P.

    1976-01-01

    There is often a correlation between "pseudoheterosexuality" and minor sexual dysfunction. Insight alone is not sufficient to provide relief, but when the patient can be helped to a comfortable acceptance of his homosexual feelings as a normal and healthy facet of his personality, very often the dysfunction is relieved. (Author)

  3. AB028. New drugs for sexual dysfunction complementary medicine for sexual dysfunction in Australia

    Science.gov (United States)

    Earle, Carolyn

    2015-01-01

    Objective In Australia both oriental and western products are available as complementary medicines. Our aim was to review the current available over-the-counter (OTC) medications for sexual dysfunction and report on this market. Methods Following an earlier published review in 2010, 37 products were reviewed that were listed on the Australian Register of Therapeutic Goods (ARTG) and registered with the Therapeutic Goods Administration (TGA). These products were manufactured in Australia and laid claim to provide treatment for sexual dysfunction. A review of these products and newer products was undertaken to establish the extent of complementary medicines in Australia for sexual dysfunction and the reported clinical experience. Results As at July 2015 there were 31 Australian manufactured OTC products registered with the TGA on the ARTG for sexual dysfunction. Twenty-four were for male sexual dysfunction, 3 for female sexual dysfunction and 4 for unisex sexual dysfunction. The main herbs used in sexual health products in Australia are tribulus terrestris, panax ginseng and horny goat weed. However, complementary medicine practitioners also promote the use of gingko Bilbo, avena sativa and damiana. Many of the ingredients found in men’s products are also in the women’s products. Although review articles for complementary medicine, sexual dysfunction and libido have been written in Australia, as far as can be investigated there are no published randomized clinical trials in the area of complementary medicine and sexual function. Conclusions Complementary medicine has reached a high degree of development in Australia. But, due to the lack of properly conducted placebo-controlled clinical trials there is not a body of supporting evidence of efficacy, certification of purity, guarantee of safety, or well-documented side effects. Even though most OTC medications for sexual health have mild side effects and some also promote general health, the lack of such evidence

  4. Associations of unhealthy lifestyle factors with sexual inactivity and sexual dysfunctions in Denmark

    DEFF Research Database (Denmark)

    Christensen, Birgitte S; Grønbaek, Morten; Pedersen, Bo V;

    2011-01-01

    Studies have linked obesity, a sedentary lifestyle, and tobacco smoking to erectile dysfunction, but the evidence linking unhealthy lifestyle factors to other sexual dysfunctions or to sexual inactivity is conflicting.......Studies have linked obesity, a sedentary lifestyle, and tobacco smoking to erectile dysfunction, but the evidence linking unhealthy lifestyle factors to other sexual dysfunctions or to sexual inactivity is conflicting....

  5. Pelvic radiotherapy and sexual dysfunction in women

    DEFF Research Database (Denmark)

    Jensen, Pernille Tine; Froeding, Ligita Paskeviciute

    2015-01-01

    focus on late effects and an increasing awareness that patient reported outcomes (PROs) i.e., patient assessment of physical, social, psychological, and sexual functioning provides the most valid information on the effects of cancer treatment. Following cure of cancer allow survivors focus on quality of...... life (QOL) issues; sexual functioning has proved to be one of the most important aspects of concern in long-term survivors. METHODS: An updated literature search in PubMed was performed on pelvic radiotherapy and female sexual functioning/dysfunction. Studies on gynaecological, urological and...... gastrointestinal cancers were included. The focus was on the period from 2010 to 2014, on studies using PROs, on potential randomized controlled trials (RCTs) where female sexual dysfunction (FSD) at least constituted a secondary outcome, and on studies reporting from modern radiotherapy modalities. RESULTS: The...

  6. Sexual Dysfunction before and after Cardiac Rehabilitation

    Directory of Open Access Journals (Sweden)

    Jörg Schumann

    2010-01-01

    variables. Methods. Analysis of patients participating in a 12-week exercise-based outpatient cardiac rehabilitation program (OCR between April 1999 and December 2007. Exercise capacity (ExC and quality of life including sexual function were assessed before and after OCR. Results. Complete data were available in 896 male patients. No sexual activity at all was indicated by 23.1% at baseline and 21.8% after OCR, no problems with sexual activity by 40.8% at baseline and 38.6% after OCR. Patients showed an increase in specific problems (erectile dysfunction and lack of orgasm from 18% to 23% (<.0001 during OCR. We found the following independent positive and negative predictors of sexual problems after OCR: hyperlipidemia, age, CABG, baseline ExC and improvement of ExC, subjective physical and mental capacity, and sense of affiliation. Conclusions. Sexual dysfunction is present in over half of the patients undergoing OCR with no overall improvement during OCR. Age, CABG, low exercise capacity are independent predictors of sexual dysfunction after OCR.

  7. [How Does Lower Urinary Tract Dysfunction Affekt Female Sexuality?].

    Science.gov (United States)

    Anding, R; Kirschner-Hermanns, R; Rantell, A; Wiedemann, A

    2016-08-01

    With increasing age many women suffer from lower urinary tract dysfunction (LUTD) and female sexual dysfunction. An increasing body of evidence supports an association between the 2 conditions. Especially women with urodynamically proved detrusor hyperactivity suffer from sexual dysfunction and there is some evidence that in patients with stress incontinence sexual health improves after successful surgery. PMID:27328304

  8. AB271. Sexual dysfunction in chronic prostatitis

    Science.gov (United States)

    Cho, In-Rae

    2016-01-01

    Chronic prostatitis/ chronic pelvic pain syndrome (CP/CPPS), or NIH category III prostatitis, is a clinical syndrome characterized by genital/ pelvic pain and lower urinary tract symptoms in the absence of urinary tract infection. CPPS is the most common prostatic disease in men younger than 50 years of age and the third most common in men older than 50 years of age. CP/CPPS is a complex entity with unclear etiology. Many articles reported that the high percentage of patients with CP/CPPS had sexual dysfunction. The most common symptoms of sexual dysfunction in chronic prostatitis patients are erectile dysfunction (ED), painful ejaculation and premature ejaculation. So we will discuss about ED and ejaculation problems in CP/CPPS patients.

  9. Sexual dysfunction in heart failure patients.

    Science.gov (United States)

    Jaarsma, Tiny; Fridlund, Bengt; Mårtensson, Jan

    2014-09-01

    Heart failure has a severe impact on different aspects of a patient's life, including sexual function. Sexual problems are common in heart failure (HF) patients, both in men and women, and are not always adequately addressed and treated in the current health care system. Several factors have been described to be related to sexual problems, such as activity intolerance, psychological factors, physiological factors, cardiac medications, recreational habits and co-morbidity. The current review summarizes knowledge that can help clinicians treat sexual dysfunction in HF patients. After a good assessment, several steps are advised, including improving HF and co-morbid conditions, discussing psychosocial problems, worries and misunderstandings, managing risk factors and considering PDE-5 inhibitors or other libido enhancing agents. PMID:24800993

  10. The Role of Sexual Assault and Sexual Dysfunction in Alcohol and Other Drug Use Disorders

    OpenAIRE

    Sanjuan, Pilar M.; Langenbucher, James W.; Labouvie, Erich

    2006-01-01

    Many women with sexual assault histories receive care in alcohol and other drug treatment programs. Affected women frequently suffer from sexual dysfunction, leading investigators to suggest self-medication may be one path to alcohol and other drug use disorders and relapse. This preliminary study examined sexual dysfunction and sexual assault in 71 women receiving treatment for addiction. Women with prior sexual assault scored higher than non-assaulted women on sexual dysfunction overall, a ...

  11. Antidepressants-Associated Sexual Dysfunction: Impact, Effects and Treatment

    OpenAIRE

    HIGGINS, AGNES; LYNCH, AILEEN MARIA; Nash, Michael

    2010-01-01

    PUBLISHED Sexual dysfunction is a common side effect of antidepressants and can have significant impact on the person?s quality of life, relationships, mental health, and recovery. The reported incidence of sexual dysfunction associated with antidepressant medication varies considerably between studies, making it difficult to estimate the exact incidence or prevalence. The sexual problems reported range from decreased sexual desire, decreased sexual excitement, diminished or...

  12. Associations between physical and mental health problems and sexual dysfunctions in sexually active Danes

    DEFF Research Database (Denmark)

    Christensen, Birgitte Schütt; Grønbaek, Morten; Osler, Merete;

    2011-01-01

    Studies have shown a high prevalence of sexual dysfunctions among individuals with a variety of health problems.......Studies have shown a high prevalence of sexual dysfunctions among individuals with a variety of health problems....

  13. Sexual dysfunctions in men treated for testicular cancer

    DEFF Research Database (Denmark)

    Rosendal, Susanne; Kristensen, Ellids; Giraldi, Annamaria G E

    2008-01-01

    Patients treated for testicular cancer have increased risk of ejaculatory, orgasmic and erectile dysfunction compared with healthy men. The underlying relations are unclear. This review describes sexual dysfunctions that are associated with various treatment modalities. One meta-analysis and 11...... understanding sexual dysfunctions in patients with testicular cancer....

  14. The impact of mental illness on sexual dysfunction.

    Science.gov (United States)

    Zemishlany, Zvi; Weizman, Abraham

    2008-01-01

    Sexual dysfunction is prevalent among psychiatric patients and may be related to both the psychopathology and the pharmacotherapy. The negative symptoms of schizophrenia limit the capability for interpersonal and sexual relationships. The first-generation antipsychotics cause further deterioration in erectile and orgasmic function. Due to their weak antagonistic activity at D2 receptors, second-generation antipsychotics are associated with fewer sexual side effects, and thus may provide an option for schizophrenia patients with sexual dysfunction. Depression and anxiety are a cause for sexual dysfunction that may be aggravated by antidepressants, especially selective serotonin reuptake inhibitors (SSRIs). SSRI-induced sexual dysfunction may be overcome by lowering doses, switching to an antidepressant with low propensity to cause sexual dysfunction (bupropion, mirtazapine, nefazodone, reboxetine), addition of 5HT2 antagonists (mirtazapine, mianserin) or coadministration of 5-phosphodiesterase inhibitors. Eating disorders and personality disorders, mainly borderline personality disorder, are also associated with sexual dysfunction. Sexual dysfunction in these cases stems from impaired interpersonal relationships and may respond to adequate psychosexual therapy. It is mandatory to identify the specific sexual dysfunction and to treat the patients according to his/her individual psychopathology, current pharmacotherapy and interpersonal relationships. PMID:18391559

  15. Sexual unresponsiveness and orgastic dysfunction: an empirical comparison.

    Science.gov (United States)

    Clement, U

    1980-01-01

    Testing a hypothesis made by Kaplan, the study investigates empirical differences between women diagnosed as "sexually unresponsive" (N = 50) vs. "orgastically dysfunctional" (N = 55). Treatment was carried out in the form of couples' therapy. The two groups show significant differences with regard to occupation (sexually unresponsive women are more frequently housewives), sexual behaviour (sexually unresponsive women have a more restricted sexual life), self-perception (sexually unresponsive women describe themselves as more timid, reserved and inhibited), and sexual attitude (sexually unresponsive women are more restrictive). Therapy success and one-year follow-up show no differences between the two groups. PMID:6965177

  16. Factors influencing fluoxetine-induced sexual dysfunction in female rats

    OpenAIRE

    Adams, Sarah; Heckard, Danyeal; Hassell, James; Uphouse, Lynda

    2012-01-01

    Treatment with selective serotonin reuptake inhibitors, such as fluoxetine, produces sexual side effects with low sexual desire being the most prevalent effect in females. In few studies have preclinical models for such antidepressant-induced sexual dysfunction been fruitful. In the current manuscript, the effects of fluoxetine on multiple measures of female sexual motivation and sexual receptivity were examined. Ovariectomized, Fischer rats were primed with 10 μg estradiol benzoate and 500 μ...

  17. Bladder, bowel, and sexual dysfunction in Parkinson's disease.

    Science.gov (United States)

    Sakakibara, Ryuji; Kishi, Masahiko; Ogawa, Emina; Tateno, Fuyuki; Uchiyama, Tomoyuki; Yamamoto, Tatsuya; Yamanishi, Tomonori

    2011-01-01

    Bladder dysfunction (urinary urgency/frequency), bowel dysfunction (constipation), and sexual dysfunction (erectile dysfunction) (also called "pelvic organ" dysfunctions) are common nonmotor disorders in Parkinson's disease (PD). In contrast to motor disorders, pelvic organ autonomic dysfunctions are often nonresponsive to levodopa treatment. The brain pathology causing the bladder dysfunction (appearance of overactivity) involves an altered dopamine-basal ganglia circuit, which normally suppresses the micturition reflex. By contrast, peripheral myenteric pathology causing slowed colonic transit (loss of rectal contractions) and central pathology causing weak strain and paradoxical anal sphincter contraction on defecation (PSD, also called as anismus) are responsible for the bowel dysfunction. In addition, hypothalamic dysfunction is mostly responsible for the sexual dysfunction (decrease in libido and erection) in PD, via altered dopamine-oxytocin pathways, which normally promote libido and erection. The pathophysiology of the pelvic organ dysfunction in PD differs from that in multiple system atrophy; therefore, it might aid in differential diagnosis. Anticholinergic agents are used to treat bladder dysfunction in PD, although these drugs should be used with caution particularly in elderly patients who have cognitive decline. Dietary fibers, laxatives, and "prokinetic" drugs such as serotonergic agonists are used to treat bowel dysfunction in PD. Phosphodiesterase inhibitors are used to treat sexual dysfunction in PD. These treatments might be beneficial in maximizing the patients' quality of life. PMID:21918729

  18. Intrinsa: An Inquiry into Female Sexual Dysfunction and Testosterone

    OpenAIRE

    Quasha, Devon R.

    2006-01-01

    In December 2004, the Food & Drug Administration rejected Intrinsa, a testosterone transdermal system for the treatment of hypoactive sexual desire disorder in surgically menopausal women. Intrinsa, as well as the FDA's decision, sparked considerable controversy. Principally, it raised questions about the use of testosterone to treat sexual dysfunction in women. This paper examines the relationship between testosterone and female sexual dysfunction and explores, specifically, whether there is...

  19. Sexual dysfunction and infertility as late effects of cancer treatment

    OpenAIRE

    SCHOVER, LESLIE R.; Marleen van der Kaaij; Eleonora van Dorst; Carien Creutzberg; Eric Huyghe; Kiserud, Cecilie E.

    2014-01-01

    Sexual dysfunction is a common consequence of cancer treatment, affecting at least half of men and women treated for pelvic malignancies and over a quarter of people with other types of cancer. Problems are usually linked to damage to nerves, blood vessels, and hormones that underlie normal sexual function. Sexual dysfunction also may be associated with depression, anxiety, relationship conflict, and loss of self-esteem. Innovations in cancer treatment such as robotic surgery or more targeted...

  20. Male sexual dysfunction and infertility associated with neurological disorders

    OpenAIRE

    Fode, Mikkel; Krogh-Jespersen, Sheila; Brackett, Nancy L.; Ohl, Dana A; Lynne, Charles M; Sønksen, Jens

    2011-01-01

    Normal sexual and reproductive functions depend largely on neurological mechanisms. Neurological defects in men can cause infertility through erectile dysfunction, ejaculatory dysfunction and semen abnormalities. Among the major conditions contributing to these symptoms are pelvic and retroperitoneal surgery, diabetes, congenital spinal abnormalities, multiple sclerosis and spinal cord injury. Erectile dysfunction can be managed by an increasingly invasive range of treatments including medica...

  1. Sexual Dysfunction and Sexual Behaviors in a Sample of Brazilian Male Substance Misusers.

    Science.gov (United States)

    Diehl, Alessandra; Pillon, Sandra Cristina; Dos Santos, Manoel Antônio; Rassool, G Hussein; Laranjeira, Ronaldo

    2016-09-01

    The aim of this study was to evaluate the potential relationship between self-reported sexual dysfunction, sexual behavior, and severity of addiction of drug users. A cross-sectional design study was conducted at an inpatient addiction treatment unit in Sao Paulo, Brazil, with a sample of 508 male drug users. Sociodemographic data, sexual behavior, and severity of dependence were evaluated.The prevalence of sexual dysfunction was 37.2% and premature ejaculation was 63.8%. Men with sexual dysfunction presented from moderate to severe level of alcohol, tobacco, and other drugs of dependence. The findings from this study are particularly relevant identifying those sociodemographic factors, severity of drug use, and sexual behavior are related to men who experience sexual dysfunction. Health promotion and motivational interventions on sexual health targeted to male drug users can contribute in reducing these at-risk behaviors. More interdisciplinary research is desirable in future in considering men's sexual health. PMID:25643586

  2. AB028. New drugs for sexual dysfunction complementary medicine for sexual dysfunction in Australia

    OpenAIRE

    Earle, Carolyn

    2015-01-01

    Objective In Australia both oriental and western products are available as complementary medicines. Our aim was to review the current available over-the-counter (OTC) medications for sexual dysfunction and report on this market. Methods Following an earlier published review in 2010, 37 products were reviewed that were listed on the Australian Register of Therapeutic Goods (ARTG) and registered with the Therapeutic Goods Administration (TGA). These products were manufactured in Australia and l...

  3. Sexual dysfunction in infertile couples: evaluation and treatment of infertility

    International Nuclear Information System (INIS)

    Objective: To evaluate the diagnostic and the predictive value of Arizona Sexual Experience Scale among primary infertile couples regarding sexual dysfunction. Methods: The cross-sectional and prospective pre, post study comprising primary infertile patients was carried out at Bulent Ecevit University Hospital, Zonguldak, Turkey. Fifty consecutive primary infertile couples not treated previously were investigated between 2003 and 2007 for the presence of sexual dysfunction by a psychiatrist. Arizona Sexual Experience Scale scoring was self-administered to determine sexual dysfunction among couples before treatment and also 3 months after the initiation of the treatment. Results: Pretreatment mean values of the index parametres in both women and men were significantly increased after treatment. Statistically significant positive correlation was observed between pre- and post-treatment total scores in both women (r=0.83; p14 (Sensitivity: 57%; Specificity: 90%) and >13 (Sensitivity: 83%; Specificity: 93%), respectively. Pre- and post-treatment scores in men were >10 (Sensitivity: 65%; Specificity: 61%), >11 (Sensitivity: 83%; Specificity: 62%), respectively. Binary logistic regression analyses revealed women's pre-treatment and post-treatment scores as a significant factor for prediction of sexual dysfunction independent of sociodemographic factors (p=0.001 and p=0.001, respectively). Conclusion: Evaluation and treatment of infertility is an important risk factor for sexual dysfunction. Pre- and post-treatment Arizona Sexual Experience Scale score could be used as a screening test for sexual dysfunction and might be used to decide pre/post-treatment consultation of couples with a specialist. (author)

  4. Survey of the prevalence of sexual dysfunctions in Kurdish women.

    Science.gov (United States)

    Arasteh, Modabber; Shams Alizadeh, Narges; Ghaderi, Ebrahim; Farhadifar, Fariba; Nabati, Ronak; Gharibi, Fardin

    2014-01-01

    This study evaluates the prevalence of female sexual dysfunctions among Kurdish women. Participants in the study were 196 women between 15 and 55 years of age who attended the gynecological clinic of Be'sat Hospital in Sanandaj Province, Iran. The authors collected relevant data using the Female Sexual Function Index. The mean score was 22.71 (SD = 5). Using a cutoff score of 26.55, the authors found that 151 women (77%) had some sexual dysfunction. Scores declined as patients' age increased; further, an older age at marriage was associated with a higher score. This study, the first about sexual dysfunctions in Kurdish society, shows that sexual dysfunctions are prevalent among women of this ethnicity. Clinicians should complete further studies to assess the factors contributing to this phenomenon. PMID:24228699

  5. SEXUAL DYSFUNCTION IN AN ADULT FEMALE WITH OBSESSIVE SEXUAL THOUGHTS: A CASE REPORT

    OpenAIRE

    Awana, Sunil; Jena, Shivananda

    2002-01-01

    We report a case of an adult married Muslim female from an orthodox background having sexual obsessions about males other than her husband and her 7 year-old son. She developed diminished sexual desire to have sex with her husband as a result of her obsessions. The role of sexual obsessions in sexual dysfunction in females is discussed.

  6. Early maladaptive schemas and sexual dysfunction in men.

    Science.gov (United States)

    Quinta Gomes, Ana Luísa; Nobre, Pedro

    2012-02-01

    The objective of the present study was to investigate the role played by early maladaptive schemas (EMS) on male sexual functioning and clarify the way these nuclear cognitive structures discriminate men with and without sexual dysfunction. A total of 242 men participated in the study (a community sample of 200 men and a clinical sample of 42 men with a DSM-IV diagnosis of sexual dysfunction). The community sample was divided into a control group (n=147) and a sub-clinical group (n=53), according to the cutoff scores of the International Index of Erectile Dysfunction (Rosen et al., 1997). All participants completed a set of measures assessing EMS (Young & Brown, 1989), sexual functioning (Rosen et al., 1997), psychopathology (Derogatis & Spencer, 1982), and cognitive schemas activated in hypothetical unsuccessful sexual situations (Nobre & Pinto-Gouveia, 2009a). Findings supported the hypothesis of a typical cognitive pattern in men with sexual difficulties. After controlling for psychopathology, men with sexual dysfunction reported more dependence/incompetence EMS and activated more difference, helpless, and particularly incompetence schemas in hypothetical unsuccessful sexual situations, in comparison to sexually healthy men. These results have important therapeutic implications for sex therapy. PMID:21975922

  7. Management and rehabilitation of neurologic patients with sexual dysfunction.

    Science.gov (United States)

    Basson, Rosemary; Bronner, Gila

    2015-01-01

    Neurologic disease frequently negatively affects sexual experience in multiple ways. The patient's sexual self-image, sexual function, propensity to sexual pain, and motivation to be sexually active may be impacted, as may the sexual experiences of the partner. Difficulties with mobility can limit both partners' sexual arousal and pleasure. Conditions associated with chronic pain or continence concerns add further distress. Thus sexual rehabilitation needs to address many areas. Comorbid depression is common and needs to be stabilized before definitive treatment of sexual dysfunction. Management strategies include cognitive behavioral therapy, mindfulness-based cognitive therapy, and sex therapy and, for erectile dysfunction and premature ejaculation, pharmacotherapy can be added. Benefit from all these modalities is confirmed in the general population but only pharmacologic treatment of erectile dysfunction has been studied in neurologic patients, where benefit is also seen. Testosterone is indicated only for comorbid testosterone deficit: very occasionally the neurologic condition causes secondary male hypogonadism. No androgen deficiency state has been identified in women. Results of testosterone treatment in women are conflicting: recruited women were not clearly dysfunctional and women with neurologic conditions have not been studied. Future research involving both partners using combined medical and psychologic therapy as followed in clinical practice is advocated. PMID:26003258

  8. Female sexual dysfunction in female genital mutilation.

    Science.gov (United States)

    Elneil, Sohier

    2016-01-01

    Female genital mutilation (FGM), otherwise known as female genital cutting (FGC), is currently very topical and has become a significant global political issue. The impact of FGM on the lives of women and girls is enormous, as it often affects both their psychology and physical being. Among the complications that are often under-reported and not always acknowledged is female sexual dysfunction (FSD). FSD presents with a complex of symptoms including lack of libido, arousability and orgasm. This often occurs in tandem with chronic urogenital pain and anatomical disruption due to perineal scarring.To treat FSD in FGM each woman needs specifically directed holistic care, geared to her individual case. This may include psychological support, physiotherapy and, on occasion, reconstructive surgery. In many cases the situation is complicated by symptoms of chronic pelvic pain, which can make treatment increasingly difficult as this issue needs a defined multidisciplinary approach for its effective management in its own right. The problems suffered by women with FGM are wholly preventable, as the practice need not happen. The current global momentum to address the social, cultural, economic and medical issues of FGM is being supported by communities, governments, non-governmental agencies (NGOs) and healthcare providers. It is only by working together that the practice can be abolished and women and girls may be free from this practice and its associated consequences. PMID:26759415

  9. Methods and methodology of sexual dysfunctions with males. Chapter 5

    International Nuclear Information System (INIS)

    Examination of patients (liquidators of Chernobyl accident) was carried out in Republican Hospital for Great War Invalids. Sexual function of patients was estimated with help G.V. Vasilenko's questionnaire 'Men's sexual function'. For consideration of sexual dysfunctions the scale for qualitative estimation of potention dysfunction level was used. For revealing of vegetative nervous system dysfunction with examined patients the Ashner effect was studied. The functional status of pituitary gland - gonad system was studied by content of hormones in blood (follicle stimulating and luteinizing hormones). Results of investigations of both the sexual function and hormone level in blood were processed by method of variation statistics. For determination of each factors influence from all acting factors on sexual function the multifactorial dispersion analysis was carried out

  10. Women's sexual dysfunction: revised and expanded definitions

    OpenAIRE

    Basson, Rosemary

    2005-01-01

    ACCEPTANCE OF AN EVIDENCE-BASED CONCEPTUALIZATION OF WOMEN'S SEXUAL RESPONSE combining interpersonal, contextual, personal psychological and biological factors has led to recently published recommendations for revision of definitions of women's sexual disorders found in the American Psychiatric Association's Diagnostic and Statistical Manual (DSM–IV-TR). DSM-IV definitions have focused on absence of sexual fantasies and sexual desire prior to sexual activity and arousal, even though the frequ...

  11. The prevalence of female sexual dysfunction among migraine patients.

    Directory of Open Access Journals (Sweden)

    Mohammad Abdollahi

    2015-03-01

    Full Text Available Female sexual dysfunction (FSD defines as any disorder in the process of sexual contact including 6 main domains, desire, arousal, lubrication, orgasm, orgasm satisfaction and pain. This study was conducted to evaluate prevalence of sexual dysfunction disorder in women with migraine headache and also find the associated factors related to migraine characteristics.A total of 69 eligible woman patients fulfilling criteria for migraine participated in this study. The Female Sexual Function Index (FSFI, a multi-dimensional self-report implement for appraisal of Female Sexual Function during the past month were utilized in this study. The information related to migraine including frequency, duration of headache attack, severity of headache according to visual analog scale (VAS score and headache impact test (HIT score were obtained using a self-administrated questionnaire.About 68.4% of patients had an FSFI score < 28. In domains of desire 73.7%, arousal 64.9%, lubrication 21.1%, orgasm 33.3%, satisfaction 17.5%, and pain 40.4% of patients reported some degree of dysfunction. Among variables related to migraine characteristics, only a significant association between frequency and sexual dysfunction were recorded (P < 0.05.FSD is prevalent among migraine patients. The frequency of a migraine attack is associated with FSD. Serotonin mechanisms such as 5HT2, 5HT3 agonist have been hypothesized as a shared etiology for migraine and sexual dysfunction.

  12. Sexual dysfunctions and sexology: social constructions, personal meanings and medicalization of sexuality

    OpenAIRE

    Alarcão, Violeta Sabina Niego Perestrelo de

    2015-01-01

    Doutoramento em Sociologia In contemporary constructions of sexuality, the discourses and practices of medicine and clinical psychology occupy a primary role. They contribute to the origin of new normative approaches to sexuality, focused on the issue of good sexual functioning. However, despite the growing attention that sexuality is receiving, the study of the social construction of sexual dysfunction remains incipient, especially in a national context. Overall, the result...

  13. USE OF TRANSDERMAL GEL OF SILDENAFIL CITRATE IN SEXUAL DYSFUNCTION

    OpenAIRE

    Harshid Patel , Amit Maniyar and Hiren Patel*

    2012-01-01

    Premature Ejaculation (PE) is one of the most common forms of Sexual Dysfunction and is thought to affect up to 30 % of men. This is the most frequently encountered sexual complaint of men and couples. The physical problem associated with premature ejaculation can be simply described as “over-sensitivity” of the penis. Psychological causes of PE are often associated with “performance anxiety” – anxiety relating to sexual intercourse. The most common treatment today is the oral treatment wi...

  14. Sexual dysfunction and cardiovascular diseases: a systematic review of prevalence

    Directory of Open Access Journals (Sweden)

    Elisabete Rodrigues Nascimento

    2013-11-01

    Full Text Available The aim of this study was to conduct a systematic review of the literature regarding the prevalence of sexual dysfunction in patients with cardiovascular diseases. An article search of the ISI Web of Science and PubMed databases using the search terms "sexual dysfunction”, “cardiovascular diseases”, “coronary artery disease", “myocardial infarct" and “prevalence” was performed. In total, 893 references were found. Non-English-language and repeated references were excluded. After an abstract analysis, 91 references were included for full-text reading, and 24 articles that evaluated sexual function using validated instruments were selected for this review. This research was conducted in October 2012, and no time restrictions were placed on any of the database searches. Reviews and theoretical articles were excluded; only clinical trials and epidemiological studies were selected for this review. The studies were mostly cross-sectional, observational and case-control in nature; other studies used prospective cohort or randomized clinical designs. In women, all domains of sexual function (desire, arousal, vaginal lubrication, orgasm, sexual dissatisfaction and pain were affected. The domains prevalent in men included erectile dysfunction and premature ejaculation and orgasm. Sexual dysfunction was related to the severity of cardiovascular disease. When they resumed sexual activity, patients with heart disease reported significant difficulty, including a lack of interest in sex, sexual dissatisfaction and a decrease in the frequency of sexual activity.

  15. The Relationship between Childhood Sexual Abuse and Sexual Dysfunction in Jamaican Adults

    Science.gov (United States)

    Swaby, Antoneal N.; Morgan, Kai A. D.

    2009-01-01

    This study examined the associations between early traumatic sexualization and later sexual dysfunction in a sample of 100 Jamaican adults while identifying the linkages between age, frequency of abuse, and gender on sexual functioning. Participants were selected via purposive and convenience sampling and divided equally into comparison and…

  16. Sexual dysfunction after radiotherapy for cancer of the cervix uteri

    International Nuclear Information System (INIS)

    Investigations of sexual consciousness and sexual dysfunction after radiotherapy for cancer of the cervix uteri were performed on patients of middle and old ages by questionnaires and questionning by doctors, and the following results were obtained. 1. Before radiotherapy, sexual activity was most prominent in their twenties and thirties. However, patients who were in fifties when this study was performed had most active sexual lives during the ages from 35 to 50 years. 2. Frequencies of sexual intercourse decreased markedly just before radiotherapy, and many patients received radiotherapy when sexual activity fell. 3. 32% of the patients have not experienced sexual intercourse after radiotherapy. 4. Decreases in the sex urge, sexuality, vaginal dicharge, and frequency of sexual intercourse after radiotherapy were recognized in 77%, 77%, 70%, and 93% respectively. 5. Patients who became unwilling to maintain sexual lives after radiotherapy because of fear about recurrence or aggravation of cancer were 38% by questionnaires and 49% by questionning by doctors. 6. Pains on sexual intercourse were found in 69% by questionnaires and 49% by questionning by doctors. Most pains occurred at pennis insertion and was thought to be due to atrophy and inflammation of vagina and external genitalia in most cases. 7. Both vaginal damages and sexual dysfunction in patients with radiotherapy following surgery for cancer of the cervix uteri, in patients with radiotherapy alone for cancer of the cervix uteri, and in patients with radiotherapy following surgery for cancer of the ovary and corpus uteri were marked, modest and mild, respectively. 8. Vaginal damage score was higher in patients treated more than 5 years before than those less than 2 years ago, but there were no differences in sexual dysfunction score between both groups. (Tsunoda, M.)

  17. Sexual dysfunction after radiotherapy for cancer of the cervix uteri

    Energy Technology Data Exchange (ETDEWEB)

    Ohkawa, R.; Takamizawa, H. (Chiba Univ. (Japan). School of Medicine); Arai, T.; Morita, S.

    1981-03-01

    Investigations of sexual consciousness and sexual dysfunction after radiotherapy for cancer of the cervix uteri were performed on patients of middle and old ages by questionnaires and questioning by doctors, and the following results were obtained. 1. Before radiotherapy, sexual activity was most prominent in their twenties and thirties. However, patients who were in fifties when this study was performed had most active sexual lives during the ages from 35 to 50 years. 2. Frequencies of sexual intercourse decreased markedly just before radiotherapy, and many patients received radiotherapy when sexual activity fell. 3. 32% of the patients have not experienced sexual intercourse after radiotherapy. 4. Decreases in the sex urge, sexuality, vaginal discharge, and frequency of sexual intercourse after radiotherapy were recognized in 77%, 77%, 70%, and 93% respectively. 5. Patients who became unwilling to maintain sexual lives after radiotherapy because of fear about recurrence or aggravation of cancer were 38% by questionaires and 49% by questioning by doctors. 6. Pains on sexual intercourse were found in 69% by questionaires and 49% by questionning by doctors. Most pains occurred at penis insertion and was thought to be due to atrophy and inflammation of vagina and external genitalia in most cases. 7. Both vaginal damage and sexual dysfunction in patients with radiotherapy following surgery for cancer of the cervix uteri, in patients with radiotherapy alone for cancer of the cervix uteri, and in patients with radiotherapy following surgery for cancer of the ovary and corpus uteri were marked, modest and mild, respectively. 8. Vaginal damage score was higher in patients treated more than 5 years before than those less than 2 years ago, but there were no differences in sexual dysfunction score between both groups.

  18. Prevalence and determinants of male sexual dysfunctions during first intercourse.

    Science.gov (United States)

    Santtila, Pekka; Sandnabba, N Kenneth; Jern, Patrick

    2009-01-01

    We explored the balance of genetic and environmental factors on sexual dysfunctions during first intercourse experience in young men. Gender role conflict theory predicts that young males should show high levels of such dysfunctions coupled with mixed affective reactions. Three thousand one hundred eighty six male twins and their siblings (M = 26.17 years, SD = 4.77) completed items on erectile dysfunction (ED), premature ejaculation (PE), contextual factors, and affective reactions during first intercourse, as well as parental attitudes towards nudity and sexuality. Twin modeling revealed a significant genetic effects for PE, but not for ED. Experiences of sexual dysfunction and both negative and positive affects during first intercourse were common among the participants. More positive parental attitudes were associated with less dysfunction and more positive affect during first intercourse. Having the first sexual intercourse with an unknown partner and while strongly intoxicated were, together with group pressure and reluctance to engage in intercourse, related to more negative and less positive affects. Erectile dysfunction during the first intercourse was related to more negative and less positive affects. PMID:19266379

  19. Sexual Dysfunction before and after Cardiac Rehabilitation

    OpenAIRE

    Jörg Schumann; Zellweger, Michael J.; Marcello Di Valentino; Simone Piazzalonga; Andreas Hoffmann

    2010-01-01

    Background. The aim of this study was to assess sexual function before and after cardiac rehabilitation in relation to medical variables. Methods. Analysis of patients participating in a 12-week exercise-based outpatient cardiac rehabilitation program (OCR) between April 1999 and December 2007. Exercise capacity (ExC) and quality of life including sexual function were assessed before and after OCR. Results. Complete data were available in 896 male patients. No sexual activity at all was indic...

  20. Sexual Dysfunction in Women with Type 2 Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Forouzan Elyasi

    2015-05-01

    Full Text Available Background: Sexual dysfunction (SD is one of the important problems in diabetic patients. The present study aimed to determine the prevalence of sexual problems in Iranian women with type 2 diabetes mellitus. Methods: A cross-sectional study was conducted among type 2 diabetic women who visited two outpatient endocrine clinics, namely Imam Hospital and Tuba clinic (Sari, Iran in 2012. Patients were asked to complete two validated questionnaires: Female Sexual Function Index (FSFI and The Hospital Anxiety and Depression Scale (HADS as well as a demographic questionnaire. Analysis was performed using descriptive and analytical tests. P<0.05 was considered to be significant. Results: One hundred and fifty women with type 2 diabetes were investigated. Most of the cases aged 40-44 years old. The mean of the total score of the FSFI questionnaire was 22. The prevalence of sexual dysfunction was 78.7% (CI: 71.4-84.4; among these, 58% (CI: 50.0-65.6 reported problems in lubrication, 50% (CI: 42.1-57.9 complained of decreased sexual desire, 50% (CI: 42.1-57.9 had problems with arousal, 47.3% (CI: 39.5-55.3 had dyspareunia, 32.7% (CI: 25.7-40.5 complained of orgasmic dysfunction and 42.7% (CI: 35.0-50.7 reported problems in sexual satisfaction. With regard to the results of the HADS questionnaire, 58.7% (CI: 50.7-66.2 of the patients had depression and 96.7% (CI: 92.4-98.6 had anxiety. Conclusion: This study showed the high prevalence of sexual dysfunction in diabetic women, especially among those complaining of depression. Health care professionals dealing with diabetic patients should be aware of possible presence of sexual dysfunction in female patients.

  1. Heart Rate Variability: A Risk Factor for Female Sexual Dysfunction.

    Science.gov (United States)

    Stanton, Amelia M; Lorenz, Tierney A; Pulverman, Carey S; Meston, Cindy M

    2015-09-01

    Heart rate variability (HRV) is a measure of autonomic nervous system activity, which reflects an individual's ability to adapt to physiological and environmental changes. Low resting HRV has been linked to several mental health conditions, including depression, anxiety, and alcohol dependence (Kemp et al. in Biological Psychiatry 67(11):1067-1074, 2010. doi:10.1016/j.biopsych.2009.12.012; Kemp et al. in PloS One, 7(2):e30777, 2012; Quintana et al. in Drug and Alcohol Dependence, 132(1-2):395-398, 2013. doi:10.1016/j.drugalcdep.2013.02.025). HRV has also been used as a method for indexing the relative balance of sympathetic nervous system (SNS) activity to parasympathetic nervous system activity. This balance--in particular, moderately dominant SNS activity--has been shown to play a significant role in women's genital sexual arousal in the laboratory; however, the role of SNS activity in clinically relevant sexual arousal function is unknown. The present study assessed the feasibility of using HRV as an index of women's self-reported sexual arousal function outside the laboratory. Sexual arousal function, overall sexual function, and resting HRV were assessed in 72 women, aged 18-39. Women with below average HRV were significantly more likely to report sexual arousal dysfunction (p < .001) and overall sexual dysfunction (p < .001) than both women with average HRV and women with above average HRV. In conclusion, low HRV may be a risk factor for female sexual arousal dysfunction and overall sexual dysfunction. PMID:26081002

  2. [A study on sexual dysfunction in female patients with alcoholics].

    Science.gov (United States)

    Seki, M; Yoshida, K; Kashimura, M

    1997-11-01

    Few investigations have been made concerning hormonal changes and dyspareunia in fertile aged women with alcoholics experiencing sexual dysfunction. Twenty-seven Japanese woman with alcoholics under 40 years of age excluded with liver cirrhosis were studied to describe alcohol drinking related to sexual dysfunction. Among 21 sexually active women, 20(95.2%) had both symptoms of dyspareunia and vaginal dryness, and only one had neither symptom. Most of patients have lower estradiol levels and 92.0% of patients have the moderately elevated prolactin levels. Eleven of them were having the second grade amenorrhea associated with hyperprolactinemia and hypergonadotropic hypogonadism and 14 were having the first grade amenorrhea. In this study alcoholic abuse women may have deeply related to the hyperprolactinemia, dyspareunia, amenorrhoea, vaginal dryness, ovarian dysfunction and fetal alcohol syndrome. PMID:9396309

  3. Breast cancer treatment and sexual dysfunction: Moroccan women's perception

    Directory of Open Access Journals (Sweden)

    Ismaili Nabil

    2011-06-01

    Full Text Available Abstract Background This exploratory prospective study evaluated women's responses to questions that asked them to describe how their body image and sexual functioning had changed since their breast cancer diagnosis to treatment. Methods A questionnaire concerning body image scale and various sexual problems experienced after diagnosis and treatment was anonymously completed by 120 women in the outpatient clinic of our hospital's Division of medical Oncology. To be eligible, subjects had to be sexually active and had histology proven breast cancer. They also had to have received treatment for breast cancer. Results 100% of participants have never spoken with their doctor about this subject. 84% of the participants continued sexual activity after treatment, but there was an increase in the incidence of sexual functioning problems which resulted in a slight reduction in the quality of their sex lives. 65% of the women experienced dyspareunia followed by lubrication difficulties (54% and the absence or reduction of sexual desire (48% and 64%, respectively while, 37% had lack of satisfaction (37%. Female orgasmic disorder and brief intercourse and arousal were reported respectively by 40% and 38% of the subjects. The sexual dysfunctions were absent before diagnosis and management of breast cancer in 91.5% subjects and of these 100% subjects complained of a deterioration of the symptomatology after the various treatments. 90% of the dysfunctions were observed after chemotherapy, 9% after surgery and 3% after radiotherapy; none of the subjects indicated the onset of dysfunctions to have been associated with hormonotherapy. 100% expressed not having received sufficient information about how the disease and treatment (including surgery might affect their sexual life. Conclusion Breast cancer and its treatment may result in significant difficulties with sexual functioning and sexual life. Addressing these problems is essential to improve the quality of

  4. Obesity and sexual dysfunction in younger Danish men

    DEFF Research Database (Denmark)

    Andersen, Ingelise; Heitman, B. L.; Wagner, Gorm

    2008-01-01

    examine a possible association between sexual disorders (erectile dysfunction, ejaculatory disorders, and sexual desire disorders) and obesity among younger men born and living in Denmark. METHODS: A community-based cross-sectional study of sexual health among Danish younger men. Questionnaires were...... to height, weight, smoking status, and alcohol consumption. Erectile dysfunction (ED) was more prevalent among these younger and older men with higher BMI, but only significant among men 20-45 years old, with an odds ratio of 2.74 (95% confidence interval 1.1-6.8). The prevalence of ED was higher...... among the younger obese nonsmokers than obese smokers. Premature ejaculation, retarded ejaculation, and sexual desire disorders were all unrelated to overweight or obesity. CONCLUSION: Obesity (BMI > or = 30 kg/m(2)) seems associated with ED among younger men aged 20-45 years. Health programs directed...

  5. Psychotherapeutic interventions for treating female sexual dysfunction.

    Science.gov (United States)

    Leiblum, Sandra R; Wiegel, Markus

    2002-06-01

    A review of the current approach to the assessment and treatment of female sexual disorders from a sex therapy perspective is described. The importance of a comprehensive evaluation of both the woman and her partner, prior to formalizing a treatment plan, is stressed. Certain interventions are common in the treatment of all female sexual difficulties, for example, education and information about female sexuality generally, communication training, non-demand pleasuring, and permission to engage in self-pleasuring. Specific interventions are also described for such issues as past sexual or physical trauma. The overall goal of treatment is increased pleasure and satisfaction, rather than perfect genital response. Finally, the factors associated with treatment success are noted along with the observation that these factors are the same factors that contribute to a successful outcome in any psychotherapeutic endeavor. PMID:12107544

  6. Adjunctive metformin for antipsychotic-induced hyperprolactinemia: A systematic review.

    Science.gov (United States)

    Bo, Qi-Jing; Wang, Zhi-Min; Li, Xian-Bin; Ma, Xin; Wang, Chuan-Yue; de Leon, Jose

    2016-03-30

    This systematic review examines adjunctive metformin therapy for the treatment of antipsychotic-induced hyperprolactinemia. A computerized search of databases in Chinese and the international databases in English provided three trials with a total of 325 patients including one randomized clinical trial (RCT) and two observational studies (single-group, before-after design). A meta-analysis could not be conducted. The quality of evidence ranged from "very low" to "moderate". Metformin patients had a significant decrease in serum prolactin level with a mean of 54.6μg/l in the three trials. In the RCT, menstruation restarted in 67% of those with menstrual disturbances versus 5% in placebo. In one observational study, 91% of patients no longer had signs or symptoms of galactorrhea. In the RCT, adverse drug reactions (ADRs) occurred at similar incidence rates among metformin and placebo patients, except that no significant increases in nausea, insomnia and agitation occurred which were not associated with discontinuations. Our systematic review indicated that adjunctive metformin significantly lowered prolactin level and relieved prolactin-related symptoms in patients with antipsychotic-induced hyperprolactinemia. Future higher quality RCTs need to verify the currently available limited evidence based on three trials which suggest that adjunctive metformin may be used effectively and safely for antipsychotic-induced hyperprolactinemia. PMID:26822064

  7. Sexual (Dys)function after Urethroplasty

    Science.gov (United States)

    2016-01-01

    There is a paucity of published literature on the andrological consequences of urethral repair. Until recently authors have focused mainly on technical aspects and objective results. Reported outcomes of urethral reconstruction surgery have traditionally focused only on urodynamic parameters such as flow rates. Patient reported outcome measures have largely been neglected and there is a scarcity of well conducted systematic studies on the subject. For these reasons whether the different components of sexual life are more or less affected by different types of urethral reconstruction remains largely unknown. In an attempt to clarify the available scientific evidence, the authors make a critical review of available literature, systematizing it by sexual domain and study type. Brief pathophysiological correlations are discussed. PMID:27051420

  8. Sexual dysfunction and infertility as late effects of cancer treatment

    Directory of Open Access Journals (Sweden)

    Leslie R. Schover

    2014-06-01

    Full Text Available Sexual dysfunction is a common consequence of cancer treatment, affecting at least half of men and women treated for pelvic malignancies and over a quarter of people with other types of cancer. Problems are usually linked to damage to nerves, blood vessels, and hormones that underlie normal sexual function. Sexual dysfunction also may be associated with depression, anxiety, relationship conflict, and loss of self-esteem. Innovations in cancer treatment such as robotic surgery or more targeted radiation therapy have not had the anticipated result of reducing sexual dysfunction. Some new and effective cancer treatments, including aromatase inhibitors for breast cancer or chemoradiation for anal cancer also have very severe sexual morbidity. Cancer-related infertility is an issue for younger patients, who comprise a much smaller percentage of total cancer survivors. However, the long-term emotional impact of being unable to have a child after cancer can be extremely distressing. Advances in knowledge about how cancer treatments may damage fertility, as well as newer techniques to preserve fertility, offer hope to patients who have not completed their childbearing at cancer diagnosis. Unfortunately, surveys in industrialised nations confirm that many cancer patients are still not informed about potential changes to their sexual function or fertility, and all modalities of fertility preservation remain underutilised. After cancer treatment, many patients continue to have unmet needs for information about restoring sexual function or becoming a parent. Although more research is needed on optimal clinical practice, current studies suggest a multidisciplinary approach, including both medical and psychosocial treatment options.

  9. Sexual dysfunction among married couples living in Kumasi metropolis, Ghana

    Directory of Open Access Journals (Sweden)

    Woode Eric

    2011-03-01

    Full Text Available Abstract Background Sexuality and its manifestation constitute some of the most complex of human behaviour and its disorders are encountered in community. Sexual dysfunction is more prevalent in women than in men. While studies examining sexual dysfunction among males and females in Ghana exist, there are no studies relating sexual problems in males and females as dyadic units. This study therefore investigated the prevalence and type of sexual disorders among married couples. Method The study participants consisted of married couples between the ages of 19 and 66 living in the province of Kumasi, Ghana. Socio-demographic information and Golombok-Rust Inventory of Sexual Satisfaction (GRISS questionnaires were administered to 200 couples who consented to take part in the study. All 28 questions of the GRISS are answered on a five-point (Likert type scale from "always", through "usually', "sometimes", and "hardly ever", to "never". Responses are summed up to give a total raw score ranging from 28-140. The total score and subscale scores are transformed using a standard nine point scale, with high scores indicating greater problems. Scores of five or more are considered to indicate SD. The study was conducted between July and September 2010. Results Out of a total of 200 married couples, 179 completed their questionnaires resulting in a response rate of 89.5%. The mean age of the participating couples as well as the mean duration of marriage was 34.8 ± 8.6 years and 7.8 ± 7.6 years respectively. The husbands (37.1 ± 8.6 were significantly older (p Conclusion The prevalence of sexual dysfunction in married couples is comparable to prevalence rates in the general male and female population and is further worsened by duration of marriage. This could impact significantly on a couple's self-esteem and overall quality of life.

  10. Sexual dysfunction and infertility as late effects of cancer treatment.

    Science.gov (United States)

    Schover, Leslie R; van der Kaaij, Marleen; van Dorst, Eleonora; Creutzberg, Carien; Huyghe, Eric; Kiserud, Cecilie E

    2014-06-01

    Sexual dysfunction is a common consequence of cancer treatment, affecting at least half of men and women treated for pelvic malignancies and over a quarter of people with other types of cancer. Problems are usually linked to damage to nerves, blood vessels, and hormones that underlie normal sexual function. Sexual dysfunction also may be associated with depression, anxiety, relationship conflict, and loss of self-esteem. Innovations in cancer treatment such as robotic surgery or more targeted radiation therapy have not had the anticipated result of reducing sexual dysfunction. Some new and effective cancer treatments, including aromatase inhibitors for breast cancer or chemoradiation for anal cancer also have very severe sexual morbidity. Cancer-related infertility is an issue for younger patients, who comprise a much smaller percentage of total cancer survivors. However, the long-term emotional impact of being unable to have a child after cancer can be extremely distressing. Advances in knowledge about how cancer treatments may damage fertility, as well as newer techniques to preserve fertility, offer hope to patients who have not completed their childbearing at cancer diagnosis. Unfortunately, surveys in industrialised nations confirm that many cancer patients are still not informed about potential changes to their sexual function or fertility, and all modalities of fertility preservation remain underutilised. After cancer treatment, many patients continue to have unmet needs for information about restoring sexual function or becoming a parent. Although more research is needed on optimal clinical practice, current studies suggest a multidisciplinary approach, including both medical and psychosocial treatment options. PMID:26217165

  11. Executive Dysfunction Predicts Delinquency But Not Characteristics of Sexual Aggression Among Adolescent Sexual Offenders.

    Science.gov (United States)

    Burton, David; Demuynck, Sophia; Yoder, Jamie R

    2014-11-25

    Our aim in this study was to evaluate executive function and its relationship to delinquency and sexual crime in adolescents incarcerated for sexual crimes. Based on self-report data, 196 male adolescent sexual offenders from a Midwest state reported high rates of executive dysfunction. Although such deficits did not relate to the number of victims of sexual abuse, severity, or degree of force used in commission of the sexual crimes, poor executive function was significantly predictive of both general delinquency and felony theft. In both measures of delinquent conduct, behavioral regulation dysfunction was predictive of the frequency of commission of the crimes, whereas metacognition was not. Research and treatment implications are offered. PMID:25428928

  12. Preclinical effects of melanocortins in male sexual dysfunction.

    Science.gov (United States)

    Shadiack, A M; Althof, S

    2008-07-01

    The neurobiology of sexual behavior involves the interrelationships between sex steroids and neurotransmitters that result in both central nervous system (CNS) effects and effects in the genitalia. Tools such as positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) scanning can help determine what areas of the brain are activated under sexual stimulation. Our understanding of the role of various neurotransmitters, neurosteroids and other CNS-acting compounds is improving. The role of CNS-acting compounds such as dopamine agonists in the treatment of male sexual dysfunction is under active investigation. Melanocortins have CNS and peripheral roles in a wide variety of bodily functions. The melanocortin agonist bremelanotide appears to act in the CNS to promote erections in preclinical models, and may also stimulate behaviors that facilitate sexual activity beyond their erectogenic effects. PMID:18552829

  13. Sexuality in eating disorders patients: etiological factors, sexual dysfunction and identity issues. A systematic review.

    Science.gov (United States)

    Castellini, Giovanni; Lelli, Lorenzo; Ricca, Valdo; Maggi, Mario

    2016-02-01

    The scientific community appears to be less interested in sexuality of eating disorders (EDs) as compared to other psychiatric or medical comorbidities. However, a clear association between sexual problems and ED psychopathology was reported from different perspectives. The overarching goal of this systematic review was to evaluate the general approach of the scientific literature toward the topic of sexuality and EDs. In particular, four different categories of research have been individuated, encompassing the role of puberty, and sexual abuse in the pathogenesis of the disorders, sexual dysfunctions, and the association between sexual orientation and EDs psychopathology. Timing of puberty with its hormonal consequences and the changes in the way persons perceive their own body represent a crucial period of life for the onset of the disorder. Sexual abuse, and especially childhood sexual abuse are well-recognized risk factors for the development of ED, determining a worse long-term outcome. Recent research overcome the approach that considers sexual activity of EDs patients, in terms of hypersexuality and dangerous sexual behaviors, considering the sexuality of EDs persons in terms of sexual desire, satisfaction, orgasm and pain. Results from this line of research are promising, and describe a clear relationship between sexual dysfunction and the core psychopathological features of EDs, such as body image disturbances. Finally, the analysis of the literature showed an association between sexual orientation and gender dysphoria with EDs psychopathology and pathological eating behaviors, confirming the validity of research developing new models of maintaining factors of EDs related to the topic of self-identity. PMID:26812878

  14. Incidence of sexual dysfunction: a prospective survey in Ghanaian females

    Directory of Open Access Journals (Sweden)

    Amidu Nafiu

    2010-09-01

    Full Text Available Abstract Background Sexuality is a complex phenomenon that is being influenced by psychological as well as physiological factors. Its dysfunction includes desire, arousal, orgasmic and sex pain disorders. The present study aimed to assess the incidence of sexual dysfunction (SD and related risk factors in a cohort of Ghanaian women. Method The Golombok Rust Inventory of Sexual Satisfaction (GRISS was administered to 400 healthy women between 18 and 58 years old (mean +/- SD: 30.1 +/- 7.9 domiciled in the Kumasi metropolis. Results The response rate was 75.3% after 99 were excluded. Of the remaining 301 women, 50% were engaged in exercise, 26.7% indulge in alcoholic beverages and only 2% were smokers. A total of 62.1% of the women had attained high education, whilst, 28.9% were married. After logistic regression analysis, alcohol emerged (OR: 2.0; CI: 1.0 - 3.8; p = 0.04 as the main risk factor for SD. The overall prevalence of SD in these subjects was 72.8%. Severe difficulties with sexual function were identified in 3.3% of the studied population. The most prevalent areas of difficulty were anorgasmia (72.4%, sexual infrequency (71.4%, dissatisfaction (77.7%, vaginismus (68.1%, avoidance of sexual intercourse (62.5%, non-sensuality (61.5% and non-communication (54.2%. Whereas 8% had severe difficulties with anorgasmia, only 6% had severe difficulties with vaginismus. Conclusion SD affects more than 70% of Ghanaian women who are sexually active. Alcohol significantly influences sexual activity.

  15. Sexual dysfunctions in schizophrenia: Professionals and patients perspectives

    OpenAIRE

    Tharoor, Hema; Kaliappan, Anandhalakshmi; Gopal, Subhashini

    2015-01-01

    Background: Sexual dysfunction (SD) is not commonly reported by persons with schizophrenia unless an enquiry is made by a doctor or staff during routine clinical visits. Materials and Methods: A cross-sectional study was carried out to determine reporting of drug-induced sexual side-effects and the attitude of the treating team in clarifying or detecting this issue. Results: A vast majority of professionals (73.2%) did not enquire about SDs in routine clinical setting and admitted that they l...

  16. Female sexual dysfunction in patients with substance-related disorders

    OpenAIRE

    Diehl, Alessandra; da Silva, Rosiane Lopes; Laranjeira, Ronaldo

    2013-01-01

    OBJECTIVE: To estimate the prevalence of female sexual dysfunction symptoms and the associated risk factors in a sample of patients with substance-related disorders admitted to a specialized in-patient care unit. METHODS: This study used a cross-section design, with eight months of data collection, conducted with substance-dependent women using structured questionnaires to collect socio-demographic data and identify their drug of choice. The Drug Abuse Screening Test, Short Alcohol Dependence...

  17. Sexual dysfunction and chronic illness: the role of flexibility in coping.

    Science.gov (United States)

    Barsky, Jennifer L; Friedman, Michael A; Rosen, Raymond C

    2006-01-01

    Sexual dysfunction is common among individuals with chronic illnesses and is associated with distress and reduced quality of life. Because of the long-term, often irreversible nature of sexual dysfunction in chronic illness and limitations of pharmacological treatments, there is a need to understand cognitive and behavioral coping processes in this population. We present a model of coping with sexual dysfunction that focuses on the construct of flexibility, including the definition of sexual functioning and its centrality to overall self-concept. We describe how this model can be applied in a comprehensive approach to treating sexual dysfunction in individuals with chronic illnesses. PMID:16809251

  18. Body mass index and sexual dysfunction in males and females in a population study

    Directory of Open Access Journals (Sweden)

    hasan karadag

    2014-01-01

    Our aim was to investigate the association of BMI with current sexual dysfunction in males and females in a nationally representative population sample after controlling for age, the presence of cardiovascular disorders, diabetes, hypertension, thyroid diseases, anxiety and depression and also menopause in women. The sample included a total of 4162 subjects (2081 females and 2081males. The most frequent sexual problem was premature ejaculation (8.8% in males and hypoactive sexual desire disorder (13.9% in females. Univariate analysis showed that hypoactive sexual desire and erectile dysfunction in males and hypoactive sexual desire, lack of pleasure from sexuality and sexual pain in females were associated with obesity. Multivariate analysis indicated that age was significantly associated with almost all types of sexual problems in both sexes. The risks of having no active sexual life, hypoactive sexual desire, lack of pleasure from sexuality and erectile dysfunction were higher in males with diabetes mellitus. Depression and anxiety were associated with all types of sexual problems in females and with no active sexual life, hypoactive sexual desire, erectile dysfunction and premature ejaculation in men. In both sexes BMI was not associated with sexual problems after the confounding factors were controlled. The association of obesity with sexual dysfunction might be mediated by other factors.

  19. Sexual medicine disparities between Asia and North America: commentary on male sexual dysfunction in Asia

    Institute of Scientific and Technical Information of China (English)

    Benjamin F Katz; Doron S Stember; Harris M Nagler

    2011-01-01

    @@ In a recently published article in Asian Journal of Andrology, Ho et al.1 examine prevalence,attitudes, and treatment patterns related to sexual dysfunction in Asia and contrast them with those of Western society.They highlight the relative paucity of data with respect to erectile dysfunction (ED), premature ejaculation, and hypogonadism in the Asian population.Although the authors make a commendable attempt to characterize sexual dysfunction in Asia, there are multiple factors that complicate interpretation of published prevalence rates.Confounding factors affecting interpretation of these studies include the methodology of identification of the studied cohorts, ages of study participants, survey response rates, definitions of ED, and strategies and lengths of time for data collection.

  20. Sexual dysfunction in men with alcoholic liver cirrhosis. A comparative study

    DEFF Research Database (Denmark)

    Jensen, S B; Gluud, C

    1985-01-01

    Sexual dysfunction in men with alcoholic cirrhosis was investigated in young (less than 56 years) outpatients with steady female partners. Sixty-one per cent (11/18) claimed sexual dysfunction, with erectile dysfunction and/or reduced sexual desire being the most common symptoms. Comparing patients...... with (n = 11) and without (n = 7) sexual dysfunction, no significant differences were found concerning a number of pertinent clinical variables. This should be interpreted with caution, however, owing to the small number of patients in each group. The prevalence and type of sexual dysfunction were not...... less than 0.025) raised prevalence of sexual dysfunction when compared to men without chronic disease (matched for age and duration of partnership)....

  1. Sexual dysfunction in patients with alcohol and opioid dependence

    Directory of Open Access Journals (Sweden)

    Sandeep Grover

    2014-01-01

    Full Text Available There are limited numbers of studies which have evaluated the sexual dysfunction (SD in patients with alcohol and opioids dependence. This article reviews the existing literature. Electronic searches were carried out using the PubMed, Google Scholar, and ScienceDirect to locate the relevant literature. Subjects addicted to heroin or on methadone maintenance treatment (MMT or buprenorphine maintenance treatment (BMT show higher rates of SD in comparison to the general population. SD rates have ranged 34-85% for heroin addicts, 14-81% for MMT, 36-83% for BMT, and 90% for naltrexone maintenance. The rates of SD in alcohol-dependent population have ranged 40-95.2%, with rates being consistently much higher in alcohol-dependent population than in the healthy controls or social drinkers. The common SDs reported have been erectile dysfunction followed by premature ejaculation, retarded ejaculation and decreased sexual desire among men, and dyspareunia and vaginal dryness among women. This review suggests that long-term use of alcohol and opioids are associated with SD in almost all domains of sexual functioning. There is a need to increase the awareness of clinicians about this association as many times SD in patients with substance abuse lead to poor treatment compliance and relapse. Further, there is a need to carry out more number of studies to understand the relationship in a better way.

  2. The Association Between Female Sexual Dysfunction and the Husband's Erectile Dysfunction: Evidence from Married Couples in Hong Kong.

    Science.gov (United States)

    Zhang, Huiping; Fan, Susan; Yip, Paul

    2016-04-01

    Little is known about the association between the sexual functioning of each partner in a heterosexual married couple. By using a community-based survey of Hong Kong Chinese couples in 2012, this study attempted to examine the relation between female sexual dysfunction and their husbands' erectile dysfunction. Among the 1,518 female and 1,059 male respondents, 944 sexually active couples were eligible for the analysis, with mean age of 39.3 ± 6.8 years (range = 21-50) for the wives and 43.6 ± 8.6 years (range = 18-80) for the husbands. Of the wives, 27.0% reported at least one form of female sexual dysfunction and 5.0% of the husbands reported erectile dysfunction. After adjusting for the female's age and other risk factors, the total and domain scores of female sexual dysfunction were not associated with her husband's erectile dysfunction except for physical pain during sexual intercourse. Therefore, whether to screen the partner's sexual function depends on the age of the female clients. PMID:25514566

  3. Sexual dysfunction among Ghanaian men presenting with various medical conditions

    Directory of Open Access Journals (Sweden)

    Quaye Lawrence

    2010-10-01

    Full Text Available Abstract Background Several medical conditions can affect and disrupt human sexuality. The alteration of sexuality in these medical conditions often hinder effective communication and empathy between the patients and their sexual partners because of cultural attitudes, social norms and negative feelings such as anxiety and guilt. Validated and standardized sexual inventories might therefore help resolve this problem. The objective of this cross-sectional study was to obtain data on the prevalence of male sexual dysfunction (SD among Ghanaians with various medical conditions residing in Kumasi. Methods The Golombok Rust Inventory of Sexual Satisfaction (GRISS was administered to 150 Ghanaian men with various medical conditions between 19 and 66 years old (mean ± standard deviation: 40.01 ± 12.32 years domiciled in the Kumasi metropolis. Results Out of the total 150 questionnaires administered, 105 (70.0% men returned the questionnaires. Questionnaires from 3 men were incomplete, leaving 102 complete and evaluable questionnaires, indicating a 68.0% response rate. Of the remaining 102 men, 88.2% were married, 70.6% had attained higher education, 88.2% were non-smokers. Whereas 54.9% were engaged in exercise, 61.8% indulged in alcoholic beverages. The prevalence of the various medical conditions include: diabetes (18%, hypertension (24.5%, migraine (11.8%, ulcer (7.8%, surgery (6.9%, STD (3.9 and others (26.5%. The prevalence of SD among the respondents in the study was 59.8%. The highest prevalence of SD was seen among ulcer patients (100%, followed by patients who have undergone surgery (75%, diabetes (70%, hypertension (50%, STD (50% and the lowest was seen among migraine patients (41.7%. Conclusions SD rate is high among Ghanaian men with medical conditions (about 60% and vary according to the condition and age.

  4. Evaluation the Frequency of Sexual Dysfunction in Infertile Men, Fatemieh Hospital, Hamadan

    OpenAIRE

    H. Babolhavaeji; M. Feizian

    2008-01-01

    Introduction & Objective: Sexual dysfunction is called to inability to get or keep a successful sexual intercourse. The term “sexual dysfunction” may also be used to describe other problems that interfere with sexual intercourse, such as inability to achieve erection and problems with ejaculation or orgasm. Damage to nerves, arteries, smooth muscles and fibrous tissues, often as a result of a disease, are the most common cause of erectile dysfunction. The aim of the present study was to evalu...

  5. Comparison of Sexual Dysfunction Using the Female Sexual Function Index following Surgical Treatments for Uterine Fibroids

    Directory of Open Access Journals (Sweden)

    Allison Ryann Louie

    2012-01-01

    Full Text Available Uterine fibroids are a common problem in women. Statistics showing 20–50% of fibroids produce symptoms and consequently patients seek surgical intervention to improve their quality of life. Treatments for fibroids are typically successful in controlling the fibroid disease, yet sexual function following invasive surgical treatments for fibroids can be jeopardized. The Sexual Function Index (FSFI is a valid instrument producing quantifiable reproducible results. In this paper three case reports are evaluated by the FSFI and compared between the following treatment groups: hysterectomy, myomectomy, and uterine embolization. Our goal is to illustrate how each of these treatment outcomes can result in sexual dysfunction and therefore decreased quality of life. Effects of invasive fibroid treatments on sexual functioning would be helpful in guiding patient’s ultimate decisions regarding treatment.

  6. Sexual Dysfunction in Aging Men With Lower Urinary Tract Symptoms

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    Mahdi Amirchaghmaghi

    2008-12-01

    Full Text Available

    Introduction: Our aim was to evaluate the relationship between lower urinary tract symptoms (LUTS, age, and sexual dysfunction in the Iranian men aged 50 to 80 years.

    Materials and Methods: A total of 357 men aged 50 to 80 years presenting at the urological clinic were enrolled in this study. The International Prostatic Symptom Score (IPSS and the International Index of Erectile Function (IIEF questionnaires were used to assess the LUTS and sexual function, respectively. The questionnaires were completed by face-to-face interview. Logistic regression model was used for multivariate analysis of the risk factors of sexual dysfunction and its domains assessed by the IIEF.

    Results: Of the patients, 332 (93% were sexually active with a median sexual attempts of 4.6 times per month. Frequency of sexual attempts was inversely related to LUTS severity (P < .001. Advanced age was positively associated with LUTS severity (r = 0.534, P < .001. Sexual dysfunction, defined as IIEF

  7. A biopsychosocial approach to women's sexual function and dysfunction at midlife: A narrative review.

    Science.gov (United States)

    Thomas, Holly N; Thurston, Rebecca C

    2016-05-01

    A satisfying sex life is an important component of overall well-being, but sexual dysfunction is common, especially in midlife women. The aim of this review is (a) to define sexual function and dysfunction, (b) to present theoretical models of female sexual response, (c) to examine longitudinal studies of how sexual function changes during midlife, and (d) to review treatment options. Four types of female sexual dysfunction are currently recognized: Female Orgasmic Disorder, Female Sexual Interest/Arousal Disorder, Genito-Pelvic Pain/Penetration Disorder, and Substance/Medication-Induced Sexual Dysfunction. However, optimal sexual function transcends the simple absence of dysfunction. A biopsychosocial approach that simultaneously considers physical, psychological, sociocultural, and interpersonal factors is necessary to guide research and clinical care regarding women's sexual function. Most longitudinal studies reveal an association between advancing menopause status and worsening sexual function. Psychosocial variables, such as availability of a partner, relationship quality, and psychological functioning, also play an integral role. Future directions for research should include deepening our understanding of how sexual function changes with aging and developing safe and effective approaches to optimizing women's sexual function with aging. Overall, holistic, biopsychosocial approaches to women's sexual function are necessary to fully understand and treat this key component of midlife women's well-being. PMID:27013288

  8. Evaluation the Frequency of Sexual Dysfunction in Infertile Men, Fatemieh Hospital, Hamadan

    Directory of Open Access Journals (Sweden)

    H. Babolhavaeji

    2008-07-01

    Full Text Available Introduction & Objective: Sexual dysfunction is called to inability to get or keep a successful sexual intercourse. The term “sexual dysfunction” may also be used to describe other problems that interfere with sexual intercourse, such as inability to achieve erection and problems with ejaculation or orgasm. Damage to nerves, arteries, smooth muscles and fibrous tissues, often as a result of a disease, are the most common cause of erectile dysfunction. The aim of the present study was to evaluate the frequency of sexual dysfunction in patients referred to Fatemieh infertility clinic, Hamadan.Materials & Methods: In this cross-sectional study all males referred to Fatemieh infertility center in 2005, were entered the study. All patients were clinically examined and their medical histories were obtained. Data such as age, accusation, education, history of smoking and opioid abusing, sexual dysfunction, inability to achieve orgasm, premature ejaculation and the frequency of intercourse were entered in the questionnaires. Data was analyzed using SPSS 13 and 2 statistical test.Results: The mean age of patients studied was 32.37.4 years (20-65 years. From 245 cases, 135 (55.1% had sexual dysfunction. The most common sexual dysfunction was premature ejaculation(38.8%. Other sexual dysfunctions were impotence with 16.3% , lack of sexual desire with 12.2% and orgasm disorder with 10.6% respectively. 65.9% patients were uneducated or had elementary education , 27.4% had diploma , and 6.7% had academic education. 23.7% of patients had addiction and 34.1% were smoker.Conclusion : This study showed that most common etiology of sexual dysfunction was premature ejaculation. Other sexual dysfunctions were: impotence, sexual desire disorder and orgasm disorder respectively.

  9. Male sexual dysfunction and infertility associated with neurological disorders

    Science.gov (United States)

    Fode, Mikkel; Krogh-Jespersen, Sheila; Brackett, Nancy L; Ohl, Dana A; Lynne, Charles M; Sønksen, Jens

    2012-01-01

    Normal sexual and reproductive functions depend largely on neurological mechanisms. Neurological defects in men can cause infertility through erectile dysfunction, ejaculatory dysfunction and semen abnormalities. Among the major conditions contributing to these symptoms are pelvic and retroperitoneal surgery, diabetes, congenital spinal abnormalities, multiple sclerosis and spinal cord injury. Erectile dysfunction can be managed by an increasingly invasive range of treatments including medications, injection therapy and the surgical insertion of a penile implant. Retrograde ejaculation is managed by medications to reverse the condition in mild cases and in bladder harvest of semen after ejaculation in more severe cases. Anejaculation might also be managed by medication in mild cases while assisted ejaculatory techniques including penile vibratory stimulation and electroejaculation are used in more severe cases. If these measures fail, surgical sperm retrieval can be attempted. Ejaculation with penile vibratory stimulation can be done by some spinal cord injured men and their partners at home, followed by in-home insemination if circumstances and sperm quality are adequate. The other options always require assisted reproductive techniques including intrauterine insemination or in vitro fertilization with or without intracytoplasmic sperm injection. The method of choice depends largely on the number of motile sperm in the ejaculate. PMID:22138899

  10. Male sexual dysfunction and infertility associated with neurological disorders

    Institute of Scientific and Technical Information of China (English)

    Mikkel Fode; Sheila Krogh-Jespersen; Nancy L Brackett; Dana A Ohl; Charles M Lynne; Jens Sonksen

    2012-01-01

    Normal sexual and reproductive functions depend largely on neurological mechanisms.Neurological defects in men can cause infertility through erectile dysfunction,ejaculatory dysfunction and semen abnormalities.Among the major conditions contributing to these symptoms are pelvic and retroperitoneal surgery,diabetes,congenital spinal abnormalities,multiple sclerosis and spinal cord injury.Erectile dysfunction can be managed by an increasingly invasive range of treatments including medications,injection therapy and the surgical insertion of a penile implant.Retrograde ejaculation is managed by medications to reverse the condition in mild cases and in bladder harvest of semen after ejaculation in more severe cases.Anejaculation might also be managed by medication in mild cases while assisted ejaculatory techniques including penile vibratory stimulation and electroejaculation are used in more severe cases.If these measures fail,surgical sperm retrieval can be attempted.Ejaculation with penile vibratory stimulation can be done by some spinal cord injured men and their partners at home,followed by in-home insemination if circumstances and sperm quality are adequate.The other options always require assisted reproductive techniques including intrauterine insemination or in vitrofertilization with or without intracytoplasmic sperm injection.The method of choice depends largely on the number of motile sperm in the ejaculate.

  11. USE OF TRANSDERMAL GEL OF SILDENAFIL CITRATE IN SEXUAL DYSFUNCTION

    Directory of Open Access Journals (Sweden)

    Harshid Patel , Amit Maniyar and Hiren Patel*

    2012-11-01

    Full Text Available Premature Ejaculation (PE is one of the most common forms of Sexual Dysfunction and is thought to affect up to 30 % of men. This is the most frequently encountered sexual complaint of men and couples. The physical problem associated with premature ejaculation can be simply described as “over-sensitivity” of the penis. Psychological causes of PE are often associated with “performance anxiety” – anxiety relating to sexual intercourse. The most common treatment today is the oral treatment with phosphodiesterase -5 (PDE-5 inhibitors. There are currently three different inhibitors available Sildenafil, Vardenafil, and Tadalafil. Sildenafil citrate is a drug of choice used in the treatment of premature ejaculation disorder. It was licensed for use in the United States in 1998; Sildenafil has shown in studies that it improves ED in men regardless of disease etiology, severity of disease, or even age. Transdermal gel has gained more and more importance because the gel based formulations are better percutaneously absorbed than creams and ointment bases. Transdermal drug delivery systems are defined as self-contained, discrete dosage forms which, when applied to the intact skin, deliver the drug, through the skin, at a controlled rate to the systemic circulation. Present Status - A review by Barry in 2001 showed, the transdermal route has vied with oral treatment as the most successful innovative research area in drug delivery.

  12. Selective Serotonin Reuptake Inhibitor-Induced Sexual Dysfunction in Adolescents: A Review.

    Science.gov (United States)

    Scharko, Alexander M.

    2004-01-01

    Objective: To review the existing literature on selective serotonin reuptake inhibitor (SSRI)-induced sexual dysfunction in adolescents. Method: A literature review of SSRI-induced adverse effects in adolescents focusing on sexual dysfunction was done. Nonsexual SSRI-induced adverse effects were compared in adult and pediatric populations.…

  13. Health-related quality of life in multiple sclerosis patients with bladder, bowel and sexual dysfunction

    NARCIS (Netherlands)

    Vitkova, Marianna; Rosenberger, Jaroslav; Krokavcova, Martina; Szilasiova, Jarmila; Gdovinova, Zuzana; Groothoff, Johan W.; van Dijk, Jitse P.

    2014-01-01

    Purpose: Bladder, bowel and sexual dysfunction are often overlooked symptoms in patients with multiple sclerosis (MS) and can be associated with lower health-related quality of life (HRQoL). The aim is to explore the association of bladder, bowel and sexual dysfunction with HRQoL in MS patients stra

  14. No effect of oral testosterone treatment on sexual dysfunction in alcoholic cirrhotic men

    DEFF Research Database (Denmark)

    Gluud, C; Wantzin, P; Eriksen, J

    1988-01-01

    . Sexual dysfunction was significantly (p less than 0.05) associated with lower serum concentrations of testosterone, non-protein-bound testosterone, and non-sex hormone-binding globulin-bound testosterone. The significant associations between sexual dysfunction and non-protein-bound and non-sex hormone......The prevalence and course of sexual dysfunction was evaluated in 221 alcoholic cirrhotic men participating in a double-blind, placebo-controlled study on the effect of oral testosterone treatment on liver disease. At entry, 67% (95% confidence limits, 61%-74%) complained of sexual dysfunction......-binding globulin-bound testosterone concentrations disappeared, however, when age, ethanol consumption, and severity of liver disease were included as covariates in the analysis. During follow-up (median 30 mo, range 1-48 mo) sexual dysfunction improved significantly (p less than 0.05) at 6, 12, and 24 mo...

  15. Prevalence and types of sexual dysfunction amongst female with diabetes mellitus

    International Nuclear Information System (INIS)

    To determine the prevalence and types of sexual dysfunction (SD) amongst female with Diabetes Mellitus (DM) in Benin City, Nigeria. This is a cross sectional study. A total of 225 female with DM and 225 female without DM who served as controls were studied. Data obtained included age, anthropometric indexes, presence and type of sexual dysfunction. Fifteen (6.6%) subjects with DM had sexual dysfunction and four (1.7%) in the control group had SD with sexual pain disorder being the commonest SD, seen in both groups. Other SD seen was lubrication disorder and sexual arousal disorder. The prevalence of SD in diabetic female was significantly higher than in the control group (6.6% vs. 1.7% p < 0.05). Sexual Dysfunction appears to be relatively uncommon amongst Nigerian women with Diabetes Mellitus. However diabetes care providets should address this issue during consultations with patients and provide treatment as this is a treatable condition. (author)

  16. Prevalence of Sexual Concerns and Sexual Dysfunction among Sexually Active and Inactive Men and Women with Screen-Detected Type 2 Diabetes

    DEFF Research Database (Denmark)

    Bjerggaard, Mette; Charles, Morten; Kristensen, Ellids; Lauritzen, Torsten; Sandbaek, Annelli; Giraldi, Annamaria

    2015-01-01

    inactive men and women with type 2 diabetes and of sexual dysfunction (SD) among sexually active. METHODS: Data from the Anglo-Danish-Dutch Study of Intensive Treatment in People with Screen-Detected Diabetes in Primary Care-Denmark study was used. A total of 1,170 Danish patients with screen-detected type...... 2 diabetes attended a health examination, including assessment of sexual concerns using self-report questionnaires and of SD using the Female Sexual Function Index (FSFI-R) and the International Index of Erectile Function (IIEF-5) instruments. MAIN OUTCOME MEASURES: The main outcome measures used...... sexually active and sexually inactive people with type 2 diabetes. Bjerggaard M, Charles M, Kristensen E, Lauritzen T, Sandbæk A, and Giraldi A. Prevalence of sexual concerns and sexual dysfunction among sexually active and inactive men and women with screen-detected type 2 diabetes. Sex Med 2015;3:302-310....

  17. Sexual Dysfunctions of HIV-Positive Men: Associated Factors, Pathophysiology Issues, and Clinical Management

    Directory of Open Access Journals (Sweden)

    Marco de Tubino Scanavino

    2011-01-01

    Full Text Available Sexual dysfunctions in HIV-positive men are associated with an increase in risky sexual behavior and decreased adherence to antiretroviral drug regimens. Because of these important public health issues, we reviewed the literature on the pathophysiology, associated factors and clinical management of sexual dysfunction in HIV-positive men. The goal was to investigate the current research on these issues. Literature searches were performed in June 2011 on PubMed, Web of Science, and PsycInfo databases with the keywords “AIDS” and “sexual dysfunction” and “HIV” and “sexual dysfunction”, resulting in 54 papers. Several researchers have investigated the factors associated with sexual dysfunction in HIV-positive men. The association between sexual dysfunction and antiretroviral drugs, particularly protease inhibitors, has been reported in many studies. The lack of standardized measures in many studies and the varying study designs are the main reasons that explain the controversial results. Despite some important findings, the pathophysiology of sexual dysfunction in the HAART era still not completely understood. Clinical trials of testosterone replacement therapy have shown the treatment to be beneficial to the improvement of sexual dysfunctions related to hypogonadism. However, there are not enough psychological intervention studies to make conclusions regarding the therapeutic effects of psychotherapy.

  18. Factors associated with sexual dysfunction in Jordanian women and their sexual attitudes

    International Nuclear Information System (INIS)

    Female sexual dysfunction (FSD) is defined as disorders of libido, arousal, and orgasm, as well as sexual pain, that leads to personal distress or interpersonal difficulties. Social aspects of FSD have been understudied. The aim of this study was to explore the social aspects of FSD and sexual attitudes of Jordanian women. Six hundred thirteen married females were studied between October 2006 and August 2007 at the National Center for Diabetes, Endocrinology and Genetics (NCDEG), Amman, Jordan. Females were interviewed using a special questionnaire that was suitable to our culture and added to the Arabic translation of the Female Sexual Function Index (FSFI) Questionnaire. Older age was associated with a decreased total FSD index and its domain scores. Women with obesity were more likely to have impaired arousability and impaired capability of reaching orgasm. About 58.5% of women reported that they prepared themselves if they had sexual desire and 68.2% reported wearing special attire for this purpose. Only 37.2% of women could ask their husband for a special excitement. FSD is prevalent in Jordan. Its social aspects are understudied and need more research in the future. (author)

  19. Determinants of sexual dysfunction among clinically diagnosed diabetic patients

    Directory of Open Access Journals (Sweden)

    Sarpong Charity

    2011-05-01

    Full Text Available Abstract Background Diabetes mellitus is a chronic disease that can result in various medical, psychological and sexual dysfunctions (SD if not properly managed. SD in men is a common under-appreciated complication of diabetes. This study assessed the prevalence and determinants of SD among diabetic patients in Tema, Greater Accra Region of Ghana. Method Sexual functioning was determined in 300 consecutive diabetic men (age range: 18-82 years visiting the diabetic clinic of Tema General Hospital with the Golombok Rust Inventory of Sexual Satisfaction (GRISS questionnaire, between November, 2010 and March, 2011. In addition to the socio-demographic characteristics of the participants, the level of glycosylated haemoglobin, fasting blood sugar (FBS and serum testosterone were assessed. All the men had a steady heterosexual relationship for at least 2 years before enrolment in the study. Results Out the 300 participants contacted, the response rate was 91.3% after 20 declined participation and 6 incomplete data were excluded All the respondents had at least basic education, 97.4% were married, 65.3% were known hypertensive, 3.3% smoked cigarettes, 27% took alcoholic beverages and 32.8% did some form of exercise. The 69.3% SD rate observed in this study appears to be related to infrequency (79.2%, non-sensuality (74.5%, dissatisfaction with sexual acts (71.9%, non-communication (70.8% and impotence (67.9%. Other areas of sexual function, including premature ejaculation (56.6% and avoidance (42.7% were also substantially affected. However, severe SD was seen in only 4.7% of the studied population. The perceived "adequate", "desirable", "too short" and "too long intra-vaginal ejaculatory latency time (IELT are 5-10, 5-10, 1-2 and 15-30 minutes respectively. Testosterone correlates negatively with glycated haemoglobin (HBA1c, FBS, perceived desirable, too short IELT, and weight as well as waist circumference. Conclusion SD rate from this study is high

  20. Sexual dysfunction improved in heroin-dependent men after methadone maintenance treatment in Tianjin, China.

    Directory of Open Access Journals (Sweden)

    Minying Zhang

    Full Text Available OBJECTIVE: To investigate whether methadone maintenance treatment (MMT is correlated with sexual dysfunction in heroin-dependent men and to determine the prevalence and risk factors of sexual dysfunction among men on MMT. METHODS: The study included a retrospective survey and a cross-sectional survey which contained interviews of 293 men who are currently engaged in MMT. The results of the two surveys were compared. For a subset of 43 participants, radioimmunoassay was additionally conducted using retrospective and prospective blood samples to test the levels of plasma testosterone and luteinizing hormone. Other study evaluations were the International Index of Erectile Function (IIEF-15, and Self-rating Depression Scale. RESULTS: Sexual dysfunction in all five IIEF-15 domains (erectile function, orgasmic function, sexual desire, intercourse satisfaction, and overall satisfaction was strongly associated with long-term use of heroin. A decrease in the severity of sexual dysfunction was associated with MMT initiation. Erectile dysfunction, lack of sexual desire, inability to orgasm, and lack of intercourse satisfaction were significantly correlated with increasing age of the participants. Methadone dose and duration of methadone treatment were not found to be associated with sexual dysfunction. The level of plasma testosterone significantly declined during methadone treatment, but results from multivariate analysis indicated low levels of testosterone were not the main cause of sexual dysfunction. No correlation between reported depression status and sexual function was found. CONCLUSIONS: While high levels of sexual dysfunction were reported by heroin-dependent men in our study before and after MMT initiation, MMT appears to be correlated with improved sexual function in the population of the study.

  1. Sexual dysfunctions after prostate cancer radiation therapy; Dysfonctions sexuelles apres irradiation pour cancer de la prostate

    Energy Technology Data Exchange (ETDEWEB)

    Droupy, S. [Service d' urologie-andrologie, CHU Caremeau, 30 - Nimes (France)

    2010-10-15

    Sexual dysfunctions are a quality of life main concern following prostate cancer treatment. After both radiotherapy and brachytherapy, sexual function declines progressively, the onset of occurrence of erectile dysfunction being 12-18 months after both treatments. The pathophysiological pathways by which radiotherapy and brachytherapy cause erectile dysfunction are multi-factorial, as patient co-morbidities, arterial damage, exposure of neurovascular bundle to high levels of radiation, and radiation dose received by the corpora cavernosa at the crurae of the penis may be important in the aetiology of erectile dysfunction. Diagnosis and treatment of postradiation sexual dysfunctions must integrate pre-therapeutic evaluation and information to provide to the patient and his partner a multidisciplinary sexual medicine management. (authors)

  2. Reduced Treatment-Emergent Sexual Dysfunction as a Potential Target in the Development of New Antidepressants

    Directory of Open Access Journals (Sweden)

    David S. Baldwin

    2013-01-01

    Full Text Available Pleasurable sexual activity is an essential component of many human relationships, providing a sense of physical, psychological, and social well-being. Epidemiological and clinical studies show that depressive symptoms and depressive illness are associated with impairments in sexual function and satisfaction, both in untreated and treated patients. The findings of randomized placebo-controlled trials demonstrate that most of the currently available antidepressant drugs are associated with the development or worsening of sexual dysfunction, in a substantial proportion of patients. Sexual difficulties during antidepressant treatment often resolve as depression lifts but can endure over long periods and may reduce self-esteem and affect mood and relationships adversely. Sexual dysfunction during antidepressant treatment is typically associated with many possible causes, but the risk and type of dysfunction vary with differing compounds and should be considered when making decisions about the relative merits and drawbacks of differing antidepressants. A range of interventions can be considered when managing patients with sexual dysfunction associated with antidepressants, including the prescription of phosphodiesterase-5 inhibitors, but none of these approaches can be considered “ideal.” As treatment-emergent sexual dysfunction is less frequent with certain drugs, presumably related to differences in their pharmacological properties, and because current management approaches are less than ideal, a reduced burden of treatment-emergent sexual dysfunction represents a tolerability target in the development of novel antidepressants.

  3. Psychological and interpersonal dimensions of sexual function and dysfunction in women: An update

    OpenAIRE

    Althof, Stanley E; Needle, Rachel B.

    2013-01-01

    Introduction We reviewed the psychological and interpersonal dimensions of female sexual function and dysfunction. Methods We identified articles published in 1970–2013 using the keywords ‘female sexual dysfunction’, ‘sexual desire’, ‘sexual arousal’, ‘female orgasmic disorder’, ‘sex therapy’, ‘psychotherapy’, ‘behaviour therapy’ and ‘Internet therapy’. Over 200 articles were reviewed (Level of evidence 2b). Results and conclusions We identified the major psychological variables affecting fem...

  4. Sexual dysfunction among female patients of reproductive age in a hospital setting in Nigeria.

    Science.gov (United States)

    Fajewonyomi, Benjamin A; Orji, Ernest O; Adeyemo, Adenike O

    2007-03-01

    Although sexual dysfunction is an important public-health problem in Nigeria, little research has been conducted on this topic in Nigeria. This cross-sectional study was conducted to determine the prevalence of sexual dysfunction and their correlates among female patients of reproductive age using a questionnaire. Respondents were recruited from the out-patients clinics of a teaching hospital setting in Ile-Ife/ Ijesa administrative health zone, Osun State, Nigeria. Of 384 female patients interviewed, 242 (63%) were sexually dysfunctional. Types of sexual dysfunction included disorder of desire (n=20; 8.3%), disorder of arousal (n=l 3; 5.4%), disorder of orgasm (n=154; 63.6%), and painful coitus (dyspareunia) (n=55; 22.7%). The peak age of sexual dysfunction was observed among the age-group of 26-30 years. Women with higher educational status were mostly affected. The reasons for unsatisfactory sexual life mainly included psychosexual factors and medical illnesses, among which included uncaring partners, present illness, excessive domestic duties, lack of adequate foreplay, present medication, competition among wives in a polygamous family setting, previous sexual abuse, and guilt-feeling of previous pregnancy termination among infertile women. The culture of male dominance in the local environment which makes women afraid of rejection and threats of divorce if they ever complain about sexually-related matters might perpetrate sexual dysfunction among the affected individuals. Sexual dysfunction is a real social and psychological problem in the local environment demanding urgent attention. It is imperative to carry out further research in society at large so that the health and lifestyles of affected women and their partners could be improved. PMID:17615910

  5. Sexual dysfunction and dissatisfaction in chronic hepatitis C patients

    Directory of Open Access Journals (Sweden)

    Bruno Cópio Fábregas

    2014-10-01

    Full Text Available Introduction The prevalence of sexual dysfunction (SD and dissatisfaction with sexual life (DSL in patients with chronic hepatitis C virus infection (CHC was jointly investigated via a thorough psychopathological analysis, which included dimensions such as fatigue, impulsiveness, psychiatric comorbidity, health-related quality of life (HRQL and sociodemographic and clinical characteristics. Methods Male and female CHC patients from an outpatient referral center were assessed using the Brief Fatigue Inventory, the Barrat Impulsiveness Scale, the Beck Depression Inventory (BDI, the Hospital Anxiety and Depression Scale, the Hamilton Anxiety Scale (HAM-A, and the World Health Organization Quality of Life Scale-Brief Version (WHOQOL-BREF. Structured psychiatric interviews were performed according to the Mini-International Neuropsychiatric Interview. SD was assessed based on specific items in the BDI (item 21 and the HAM-A (item 12. DSL was assessed based on a specific question in the WHOQOL-BREF (item 21. Multivariate analysis was performed according to an ordinal linear regression model in which SD and DSL were considered as outcome variables. Results SD was reported by 60 (57.1% of the patients according to the results of the BDI and by 54 (51.4% of the patients according to the results of the HAM-A. SD was associated with older age, female gender, viral genotype 2 or 3, interferon-α use, impulsiveness, depressive symptoms, antidepressant and benzodiazepine use, and lower HRQL. DSL was reported by 34 (32.4% of the patients and was associated with depressive symptoms, anxiety symptoms, antidepressant use, and lower HRQL. Conclusions The prevalence of SD and DSL in CHC patients was high and was associated with factors, such as depressive symptoms and antidepressant use. Screening and managing these conditions represent significant steps toward improving medical assistance and the HRQL of CHC patients.

  6. Investigation of the difference between the expression and presence of sexual symptoms and dysfunction in depressed women treated with fluoxetine

    Directory of Open Access Journals (Sweden)

    Ali Fakhari

    2015-11-01

    Full Text Available Introduction: The present study aimed at investigating the difference between the expression and presence of sexual symptoms and dysfunction in depressed women treated with fluoxetine, and the possibility of sexual dysfunction following consumption of fluoxetine. Methods: This cross-sectional analytic study was conducted on 44 women candidates for receiving fluoxetine after the diagnosis of depression. Patients’ complaints of sexual dysfunction were collected and compared using Arizona Sexual Experiences Scale (ASEX questionnaire during their first visit and 2 months after receiving fluoxetine. Two-way data were analyzed using chi-square test, and Wilcoxon Signed Ranks test was used to study ordinal variables in SPSS software. Results: This study indicates that there is a significant difference between the final score of the ASEX questionnaire and that of each question before and after the consumption of fluoxetine. Using ASEX scale, it was indicated that 11 (25.0% and 27 (61.4% of participants suffered from sexual dysfunction at their first and second visit, respectively, and that there is a correlation between the expression of sexual dysfunction symptoms and sexual dysfunction disorder. Conclusion: Results indicate that consumption of fluoxetine causes sexual dysfunction, and there is a correlation between the expression of sexual dysfunction symptoms and sexual dysfunction disorder. Moreover the fewer participants complain about symptoms, the more the chance of sexual dysfunction.

  7. Laser irradiation of penile blood as treatment of sexual dysfunctions

    Science.gov (United States)

    Koultchavenia, Ekaterina V.; Khomyakov, Victor T.

    2001-05-01

    40-60% of the men of average age suffer from the violations of sexual functions. Impotence doesn't make direct threat to life; nevertheless this disease essentially reduces quality of life, and consequently deserves the most steadfast attention. There are many methods of treatment of erectile dysfunction. However they are connected with a reception of medicines, which is expensive and has a number of contraindications, or with invasive procedures, or with surgical intervention, that also not always is desirable. We have developed the original device permitting to cause passive erection by creation of a local decompression. The second stage is the effect by an infrared laser radiation (denseness of a potency 4.2 mWt/sm2, continuous radiation with length of a wave 0.89 microns, exposition 5 minutes) on erection glans penis. We observed 24 patients with the complaints on insufficient erection (18), premature ejaculation (6); 2 patients in addition presented the complaint on small sizes of the penis. Age of the patients was 24-46 years, on the average 34.3 years. All have received treatment from 15 sessions in day.

  8. The Gay Men Sex Studies: prevalence of sexual dysfunctions in Belgian HIV+ gay men

    OpenAIRE

    Vansintejan J; Janssen J; Van De Vijver E; Vandevoorde J; Devroey D

    2013-01-01

    Johan Vansintejan, Joris Janssen, Erwin Van De Vijver, Jan Vandevoorde, Dirk Devroey Department of Family Medicine, Vrije Universiteit Brussel (VUB), Brussels, Belgium Abstract: The aim of this Internet-based survey was to investigate the prevalence and associated predictors of sexual dysfunctions in Belgian self-reported HIV-positive men who have sex with other men. Of the 72 participants, 56% had a mild-to-severe erectile dysfunction, and 15% reported a hypoactive sexual desire disorder. Th...

  9. The Gay Men Sex Studies: prevalence of sexual dysfunctions in Belgian HIV+ gay men

    OpenAIRE

    Vansintejan, Johan

    2013-01-01

    Johan Vansintejan, Joris Janssen, Erwin Van De Vijver, Jan Vandevoorde, Dirk Devroey Department of Family Medicine, Vrije Universiteit Brussel (VUB), Brussels, Belgium Abstract: The aim of this Internet-based survey was to investigate the prevalence and associated predictors of sexual dysfunctions in Belgian self-reported HIV-positive men who have sex with other men. Of the 72 participants, 56% had a mild-to-severe erectile dysfunction, and 15% reported a hypoactive sexual desire disorder. T...

  10. Prevalence of Sexual Concerns and Sexual Dysfunction among Sexually Active and Inactive Men and Women with Screen‐Detected Type 2 Diabetes

    Science.gov (United States)

    Charles, Morten; Kristensen, Ellids; Lauritzen, Torsten; Sandbæk, Annelli; Giraldi, Annamaria

    2015-01-01

    Abstract Introduction Type 2 diabetes negatively impacts sexual health. Only limited information is available regarding sexual health among sexually inactive patients with type 2 diabetes. Aim The aim of this study was to examine the prevalence of sexual concerns among sexually active and sexually inactive men and women with type 2 diabetes and of sexual dysfunction (SD) among sexually active. Methods Data from the Anglo–Danish–Dutch Study of Intensive Treatment in People with Screen‐Detected Diabetes in Primary Care‐Denmark study was used. A total of 1,170 Danish patients with screen‐detected type 2 diabetes attended a health examination, including assessment of sexual concerns using self‐report questionnaires and of SD using the Female Sexual Function Index (FSFI‐R) and the International Index of Erectile Function (IIEF‐5) instruments. Main Outcome Measures The main outcome measures used regarding sexual concerns are the following: prevalence of failure to fill sexual needs, of experiencing sexual distress, finding it important to have a good sexual life, and additionally, prevalence of SD. Results Data regarding sexual activity status during the last 12 months were available among 583 men and 377 women. Seventeen percent of men and 47% of women reported to be sexually inactive, among whom 57% of men and 42% of women reported failure to fill sexual needs; 31% of men and 10% of women that it was important to have a good sexual life, and 32% of men and 11% of women that they were experiencing sexual distress. Around half of men and women were excluded from the SD analysis, mainly because of reporting lack of sexual intercourse during the last 4 weeks. Among those included, 54% of men and 12% of women were found to have SD. Conclusions Sexual inactivity is highly prevalent among middle‐aged and older men and women with early type 2 diabetes and these patients often have sexual concerns. The high exclusion rates when assessing SD using the FSFI

  11. Sexual (dys)function after radiotherapy for prostate cancer: a review

    International Nuclear Information System (INIS)

    Purpose: Prostate cancer has become the most common nonskin malignant neoplasm in older men in Western countries. As treatment efficacy has improved, issues related to posttherapy quality of life and sexual functioning have become more important. Methods and materials: We discuss the various methods used to evaluate erectile and sexual dysfunction and the definition of potency. The etiologies of erectile dysfunction after external beam radiotherapy and brachytherapy for prostate cancer are also reviewed. The literature is summarized, and comparative studies of radiation and surgery are surveyed briefly. Results: Rates of erectile dysfunction vary from 6 to 84% after external beam radiotherapy and from 0 to 51% after brachytherapy. In most of the studies, the analysis is retrospective, the definition of erectile dysfunction is not clear, only one question about sexual functioning is asked, and nonvalidated instruments are used. The etiology of erectile dysfunction after radiation for prostate cancer is not completely understood. Conclusions: Because erectile function is only one component of sexual function, it is necessary to assess sexual desire, satisfaction, frequency of intercourse, and other such factors when evaluating the effects of therapy. Patients should be offered sexual counseling and informed about the availability of effective treatments for erectile dysfunction, such as sildenafil, intracavernosal injection, and vacuum devices

  12. Glucagon-like peptide-1 analogs against antipsychotic-induced weight gain

    DEFF Research Database (Denmark)

    Ebdrup, Bjørn H; Knop, Filip K; Ishøy, Pelle L;

    2012-01-01

    already compromised in normal weight patients with schizophrenia. Here we outline the current strategies against antipsychotic-induced weight gain, and we describe peripheral and cerebral effects of the gut hormone glucagon-like peptide-1 (GLP-1). Moreover, we account for similarities in brain changes...... between schizophrenia and overweight patients. DISCUSSION: Current interventions against antipsychotic-induced weight gain do not facilitate a substantial and lasting weight loss. GLP-1 analogues used in the treatment of type 2 diabetes are associated with significant and sustained weight loss in...... overweight patients. Potential effects of treating schizophrenia patients with antipsychotic-induced weight gain with GLP-1 analogues are discussed. CONCLUSIONS: We propose that adjunctive treatment with GLP-1 analogues may constitute a new avenue to treat and prevent metabolic and cerebral deficiencies in...

  13. Role of 5-HT2C receptor gene variants in antipsychotic-induced weight gain

    Directory of Open Access Journals (Sweden)

    Brandl EJ

    2011-08-01

    Full Text Available Tessa JM Wallace, Clement C Zai, Eva J Brandl, Daniel J MüllerNeurogenetics Section, Center for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, ON, CanadaAbstract: Antipsychotic-induced weight gain is a serious side effect of antipsychotic medication that can lead to increased morbidity, mortality, and non-compliance in patients. Numerous single nucleotide polymorphisms have been studied for association with antipsychotic-induced weight gain in an attempt to find genetic predictors of this side effect. An ability to predict this side effect could lead to personalized treatment plans for predisposed individuals, which could significantly decrease the prevalence and severity of weight gain. Variations in the serotonin receptor 2c gene (HTR2C have emerged as promising candidates for prediction of antipsychotic-induced weight gain. Specifically, the well-studied -759C/T promoter polymorphism has been associated with weight gain in diverse populations, although some studies have reported no association. This discrepancy is likely due to heterogeneity in study design with respect to ethnicity, treatment duration, and other variables. Notably, the association between HTR2C and antipsychotic-induced weight gain appears strongest in short-term studies on patients with limited or no previous antipsychotic treatment. Other, less extensively studied promoter polymorphisms (-697C/G, -997G/A, and -1165A/G have also emerged as potential predictors of antipsychotic-induced weight gain. Conversely, the well-studied intronic polymorphism Cys23Ser does not appear to be associated. With further research on both HTR2C and other genetic and environmental predictors of antipsychotic-induced weight gain, a predictive test could one day be created to screen patients and provide preventative or alternative treatment for those who are predisposed to this serious side effect.Keywords: HTR2C, pharmacogenomics, promoter polymorphism

  14. Major Depressive Disorder, Obsessive-Compulsive Disorder, and Generalized Anxiety Disorder: Do the Sexual Dysfunctions Differ?

    OpenAIRE

    Kendurkar, Arvind; Kaur, Brinder

    2008-01-01

    Objectives: Major depressive disorder (MDD), obsessive-compulsive disorder (OCD), and generalized anxiety disorder (GAD) are known to have significant impact on sexual functioning. They have been studied individually. Therefore, this study was planned to compare the sexual dysfunction between MDD, OCD, and GAD with healthy subjects as controls.

  15. Sexual dysfunctions and difficulties in denmark: prevalence and associated sociodemographic factors

    DEFF Research Database (Denmark)

    Christensen, Birgitte S; Grønbaek, Morten; Osler, Merete;

    2011-01-01

    Sexual dysfunctions and difficulties are common experiences that may impact importantly on the perceived quality of life, but prevalence estimates are highly sensitive to the definitions used. We used questionnaire data for 4415 sexually active Danes aged 16-95 years who participated in a nationa...

  16. Sexual dysfunction and hormonal changes in first episode psychosis patients on olanzapine or risperidone

    NARCIS (Netherlands)

    M. van Bruggen; T. van Amelsvoort; L. Wouters; P. Dingemans; L. de Haan; D. Linszen

    2009-01-01

    Atypical antipsychotics interfere with central and peripheral neurotransmitter systems and with hormonal production. In this study we compared the effect of olanzapine and risperidone on hormonal state and sexual function (by using the Questionnaire for Sexual Dysfunction, QSD) in 40 patients with a

  17. Sexual dysfunction in the peri- and postmenopause. Status of incidence, pharmacological treatment and possible risks. A secondary publication

    DEFF Research Database (Denmark)

    Gregersen, Nina; Jensen, Pernille Tine; Giraldi, Annamaria Elena

    2006-01-01

    The frequency of female sexual dysfunction increases with age, and the menopausal transition has a negative effect on the sexuality. Pharmacological treatment options for female sexual dysfunction during the peri- and post-menopause include hormone therapy or sildenafil. A limited number of rando...

  18. The prevalence of sexual dysfunction in the female health care providers in Jeddah, Saudi Arabia

    OpenAIRE

    Rouzi, Abdulrahim A; Nora Sahly; Dana Sawan; Souzan Kafy; Faten Alzaban

    2015-01-01

    The objective of this study was to determine the prevalence of sexual dysfunction in Saudi and non-Saudi female health care providers in Jeddah, Saudi Arabia. One -hundred twenty (60 Saudi and 60 non-Saudi) sexually active female health care professionals in Jeddah, Saudi Arabia, were anonymously surveyed using the English version of the female sexual function index questionnaire. The individual domain scores for pain, arousal, lubrication, orgasm, satisfaction, pain, and overall score for th...

  19. Clitoral therapy device for treatment of sexual dysfunction in irradiated cervical cancer patients

    International Nuclear Information System (INIS)

    Purpose: The purpose of this pilot study was to evaluate the efficacy of the clitoral therapy device (Eros Therapy) in alleviating sexual dysfunction in irradiated cervical cancer patients. Methods and materials: Eligible patients had a history of cervical cancer treated with radiotherapy and self-reported sexual dysfunction of sexual arousal and/or orgasmic disorders. Patients used the noninvasive, nonpharmacologic clitoral therapy device using a hand-held, battery-powered vacuum to cause clitoral engorgement four times weekly for 3 months during foreplay and self-stimulation. Study instruments included the Female Sexual Function Index, Derogatis Interview for Sexual Functioning, and Dyadic Adjustment Scale. The outcome evaluation was performed at 3 months. Results: Between 2001 and 2002, 15 women were enrolled and 13 completed the study. The median patient age and radiotherapy-enrollment interval was 43.5 years and 2 years, respectively. At baseline, all patients reported symptoms of sexual arousal and/or orgasmic disorders, and some also had sexual desire and pain disorders. At 3 months, statistically significant improvements were seen in all domains tested, including sexual desire, arousal, lubrication, orgasm, sexual satisfaction, and reduced pain. The median Female Sexual Function Index total score increased from 17 to 29.4 (maximal score, 36; p <0.001). The median Derogatis Interview for Sexual Functioning total raw score increased from 46 to 95 (maximal score, 118; p <0.001). At baseline, the Derogatis Interview for Sexual Functioning total T-score corresponded to the bottom 10th percentile of normal sexual functioning. At 3 months, the total T-score placed the patients at the normalcy cutoff. Gynecologic examinations revealed improved mucosal color and moisture and vaginal elasticity and decreased bleeding and ulceration. Conclusion: Our results from this pilot study suggest that the clitoral therapy device may alleviate sexual dysfunction in irradiated

  20. Clinical Assessment of Tribulus terrestris Extract in the Treatment of Female Sexual Dysfunction.

    Science.gov (United States)

    Gama, Carlos Rb; Lasmar, Ricardo; Gama, Gustavo F; Abreu, Camila S; Nunes, Carlos P; Geller, Mauro; Oliveira, Lisa; Santos, Alessandra

    2014-01-01

    This is a qualitative-quantitative study based on hospital records of female patients of reproductive age, presenting sexual dysfunction, and treated with 250 mg Tribulus terrestris extract (1 tablet thrice daily for 90 days). Safety monitoring included vital signs, physical examination, laboratory tests, and occurrence of adverse events. Efficacy analysis included results of the Female Sexual Function Index (FSFI), dehydroepiandrosterone (DHEA) levels together with total and free testosterone, and the patient and physician assessments. There was a statistically significant improvement in total FSFI scores (P terrestris extract is safe and effective in the treatment of female sexual dysfunction. PMID:25574150

  1. Animal models of female sexual dysfunction: basic considerations on drugs, arousal, motivation and behavior.

    Science.gov (United States)

    Ågmo, Anders

    2014-06-01

    Female sexual dysfunctions are a heterogeneous group of symptoms with unknown but probably varying etiology. Social factors may contribute both to the prevalence and to the origin of these dysfunctions. The present review focuses on female hypoactive sexual desire disorder, sexual arousal disorder and orgasmic disorder. These disorders are generally the most common, according to epidemiological studies, and they can all be considered as disorders of motivation. An incentive motivational model of sexual behavior, applicable to humans as well as to non-human animals, is described and the dysfunctions placed into the context of this model. It is shown that endocrine alterations as well as observable alterations in neurotransmitter activity are unlikely causes of the disorders. A potential role of learning is stressed. Nevertheless, the role of some transmitters in female rodent sexual behavior is analyzed, and compared to data from women, whenever such data are available. The conclusion is that there is no direct coincidence between effects on rodent copulatory behavior and sexual behavior in women. Based on these and other considerations, it is suggested that sexual approach behaviors rather than copulatory reflexes in rodents might be of some relevance for human sexual behavior, and perhaps even for predicting the effects of interventions, perhaps even the effects of drugs. Female copulatory behaviors, including the proceptive behaviors, are less appropriate. The common sexual dysfunctions in women are not problems with the performance of copulatory acts, but with the desire for such acts, by feeling aroused by such acts and experiencing the pleasure expected to be caused by such acts. Finally, it is questioned whether female sexual dysfunctions are appropriate targets for pharmacological treatment. PMID:24125786

  2. Definitions of women's sexual dysfunction reconsidered : advocating expansion and revision

    NARCIS (Netherlands)

    Basson, R; Leiblum, S; Brotto, L; Derogatis, L; Fourcroy, J; Fugl-Meyer, K; Graziottin, A; Heiman, [No Value; Laan, E; Meston, C; Schover, L; van Lankveld, J; Schultz, WW

    2003-01-01

    In light of various shortcomings of the traditional nosology of women's sexual disorders for both clinical practice and research, an international multi-disciplinary group has reviewed the evidence for traditional assumptions about women's sexual response. It is apparent that fullfillment of sexual

  3. A Preliminary Study of Sexual Dysfunction in Male Opioid-Dependants under Methadone Maintenance Treatment

    Directory of Open Access Journals (Sweden)

    Masoudeh Babakhanian

    2011-08-01

    Full Text Available Introduction: Sexual dysfunction is one of the prevalent problems of opiate-dependent patients. The current preliminarily study examines sexual dysfunction in a group of opiate-dependent patients before and after 6 months of MMT. Methods: The current study is a cross-sectional study. The numbers of 30 opiate-dependent patients were selected of Cheraghiyan clinic in Damghan, Iran. Demographics questionnaire and the International Index of Erectile Function were administered before and after treatment. Results: Erectile function showed an increase and intercourse satisfactions completely improved. Sexual desire and overall satisfaction increased, showing slight improvement while orgasmic function increased showing no improvement. Discussion: The findings revealed the prevalence of sexual dysfunction and improvement of some component in patients after treatment. Future studies are needed to explore the roles of other factors.

  4. The Role of Big Five Personality Factors and Defense Mechanisms in Predicting Quality of Life in Sexually Dysfunctional Female Patients

    OpenAIRE

    Salary, S; Roshan, R.; M. moghaddathin

    2015-01-01

    Sexual dysfunction can lead to behavioral problems and reduction in a person's quality of life. In 50 % of patients with personality disorders, there is also sexual dysfunction. Psychoanalysis approach attributes the cause of sexual dysfunction to a kind of fundamental anxiety as well as the use of immature mechanisms in these patients. The purpose of this study was to investigate the role of big five personality traits and defensive mechanisms in predicting these patients' quality of life. S...

  5. Functional neuroanatomy in depressed patients with sexual dysfunction: blood oxygenation level dependent functional MR imaging

    International Nuclear Information System (INIS)

    To demonstrate the functional neuroanatomy associated with sexual arousal visually evoked in depressed males who have underlying sexual dysfunction using Blood Oxygenation Level Dependent-based fMRI. Ten healthy volunteers (age range 21-55: mean 32.5 years), and 10 depressed subjects (age range 23-51: mean 34.4 years, mean Beck Depression Inventory score of 39.6 ± 5.9, mean Hamilton Rating Scale Depression (HAMD)-17 score of 33.5 ± 6.0) with sexual arousal dysfunction viewed erotic and neutral video films during functional magnetic resonance imaging (fMRI) with 1.5 T MR scanner (GE Signa Horizon). The fMRI data were obtained from 7 oblique planes using gradient-echo EPI (flip angle/TR/TE=90 .deg. /6000 ms/50 ms). The visual stimulation paradigm began with 60 sec of black screen, 150 sec of neutral stimulation with a documentary video film, 30 sec of black screen, 150 sec of sexual stimulation with an erotic video film followed by 30 sec of black screen. The brain activation maps and their quantification were analyzed by SPM99 program. There was a significant difference of brain activation between two groups during visual sexual stimulation. In depressed subjects, the level of activation during the visually evoked sexual arousal was significantly less than that of healthy volunteers, especially in the cerebrocortical areas of the hypothalamus, thalamus, caudate nucleus, and inferior and superior temporal gyri. On the other hand, the cerebral activation patterns during the neutral condition in both groups showed no significant differences (ρ < 0.01). This study is the first demonstration of the functional neuroanatomy of the brain associated with sexual dysfunction in depressed patients using fMRI. In order to validate our physiological neuroscience results, further studies that would include patients with other disorders and sexual dysfunction, and depressed patients without sexual dysfunction and their treatment response are needed

  6. Functional neuroanatomy in depressed patients with sexual dysfunction: blood oxygenation level dependent functional MR imaging

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Jong Chul [Chonnam National Univ. Hospital, Kwangju (Korea, Republic of)

    2004-06-15

    To demonstrate the functional neuroanatomy associated with sexual arousal visually evoked in depressed males who have underlying sexual dysfunction using Blood Oxygenation Level Dependent-based fMRI. Ten healthy volunteers (age range 21-55: mean 32.5 years), and 10 depressed subjects (age range 23-51: mean 34.4 years, mean Beck Depression Inventory score of 39.6 {+-} 5.9, mean Hamilton Rating Scale Depression (HAMD)-17 score of 33.5 {+-} 6.0) with sexual arousal dysfunction viewed erotic and neutral video films during functional magnetic resonance imaging (fMRI) with 1.5 T MR scanner (GE Signa Horizon). The fMRI data were obtained from 7 oblique planes using gradient-echo EPI (flip angle/TR/TE=90 .deg. /6000 ms/50 ms). The visual stimulation paradigm began with 60 sec of black screen, 150 sec of neutral stimulation with a documentary video film, 30 sec of black screen, 150 sec of sexual stimulation with an erotic video film followed by 30 sec of black screen. The brain activation maps and their quantification were analyzed by SPM99 program. There was a significant difference of brain activation between two groups during visual sexual stimulation. In depressed subjects, the level of activation during the visually evoked sexual arousal was significantly less than that of healthy volunteers, especially in the cerebrocortical areas of the hypothalamus, thalamus, caudate nucleus, and inferior and superior temporal gyri. On the other hand, the cerebral activation patterns during the neutral condition in both groups showed no significant differences ({rho} < 0.01). This study is the first demonstration of the functional neuroanatomy of the brain associated with sexual dysfunction in depressed patients using fMRI. In order to validate our physiological neuroscience results, further studies that would include patients with other disorders and sexual dysfunction, and depressed patients without sexual dysfunction and their treatment response are needed.

  7. Loxapine for Reversal of Antipsychotic-Induced Metabolic Disturbances: A Chart Review

    Science.gov (United States)

    Jain, Seema; Andridge, Rebecca; Hellings, Jessica A.

    2016-01-01

    Loxapine substitution is a promising option for patients with autism spectrum disorder (ASD) who develop antipsychotic-induced metabolic illness. We performed a chart review of 15 adolescents and adults meeting DSM-IV-TR criteria for ASD, all with antipsychotic-associated weight gain, who received low dose loxapine in an attempt to taper or…

  8. Terapia sexual y normalización: significados del malestar sexual en mujeres y hombres diagnosticados con disfunción sexual Sexual therapy and normalization: meanings of sexual discontent in women and men diagnosed with sexual dysfunction

    Directory of Open Access Journals (Sweden)

    Eva Alcántara Zavala

    2009-01-01

    Full Text Available En los últimos veinticinco años, instituciones y profesionales interesados en brindar terapia sexual se han establecido en las áreas urbanas de México. El tratamiento de las disfunciones sexuales es tanto farmacéutico como conductual. Estudios sociohistóricos han señalado las particularidades y limitaciones de las aproximaciones biomédicas a los malestares sexuales. En este estudio presentamos una serie de reflexiones en torno a la noción de disfunción sexual y los presupuestos bioconductuales que sostienen su tratamiento en terapia sexual. El objetivo del estudio fue comprender los significados del malestar sexual en un grupo abierto y mixto de terapia sexual, que se llevó a cabo en la ciudad de México en sesiones semanales de dos horas. Aunque se realizaron observaciones de las sesiones durante un año, para un análisis detallado se seleccionaron veinte de ellas. En esas sesiones participaron intermitentemente tres mujeres terapeutas sexuales, y quince mujeres y diez hombres diagnosticados con algún tipo de disfunción sexual. Un análisis cualitativo de los diálogos demostró que los significados de malestar sexual están fuertemente ligados al establecimiento de un modelo ideal de normalidad sexual. Este modelo se refiere a un estándar de desempeño sexual al cual las personas debían adaptarse con el objetivo de cumplir con los estándares de normalidad. El género es un elemento constitutivo de dicho modelo, inequidades y relaciones significantes de poder son reguladas, reproducidas y reafirmadas a través del modelo que sostiene la terapia sexual.In the last 25 years, professionals and institutions who are interested in spreading sexual therapy have become firmly established in urban areas of Mexico. The treatment of sexual dysfunctions includes both pharmaceutical treatment and sexual training. Sociohistorical studies have indicated the particularities and limitations of biomedical approaches to sexual difficulties. In

  9. 亚洲男性性功能障碍%Male sexual dysfunction in Asia

    Institute of Scientific and Technical Information of China (English)

    Christopher CK Ho; Praveen Singam; Goh Eng Hong; Zulkifii Md Zainuddin

    2011-01-01

    Sex has always been a taboo subject in Asian society. However, over the past few years, awareness in the field of men's sexual health has improved, and interest in sexual health research has recently increased. The epidemiology and prevalence of erectile dysfunction,hypogonadism and premature ejaculation in Asia are similar in the West. However, several issues are specific to Asian males, including culture and beliefs, awareness, compliance and the availability of traditional/complementary medicine. In Asia, sexual medicine is still in its infancy, and a concerted effort from the government, relevant societies, physicians and the media is required to propel sexual medicine to the forefront of health care.

  10. Sexual dysfunction in patients with schizophrenia treated with conventional antipsychotics or risperidone

    Directory of Open Access Journals (Sweden)

    Hong Liu-Seifert

    2009-01-01

    Full Text Available Hong Liu-Seifert1, Bruce J Kinon1, Christopher J Tennant2, Jennifer Sniadecki1, Jan Volavka31Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, USA; 2CJT Biomedical Consulting, South Lake Tahoe, CA, USA; 3New York University, New York, NY, USAObjective: To better understand sexual dysfunction in patients with schizophrenia and its associations with prolactin and reproductive hormones.Methods: This was a secondary analysis of an open-label, one-day study (N = 402. The primary objective of the study was to assess the prevalence of hyperprolactinemia in patients with schizophrenia who had been treated with conventional antipsychotics or risperidone. Other atypical antipsychotics available at the time of the study were not included due to a more favorable prolactin profile.Results: The majority of patients (59% of females and 60% of males reported impairment of sexual function. In postmenopausal females, risk of impaired sexual interest was increased by 31% for every 10 ng/ml increase in prolactin (p = 0.035. In males, lower testosterone was associated with higher prolactin (p < 0.001 and with orgasmic (p = 0.004 and ejaculatory dysfunction (p = 0.028.Conclusion: These findings suggest that hyperprolactinemia may be associated with sexual dysfunction. They also provide more information on the relationships between prolactin, reproductive hormones, and sexual dysfunction. Sexual dysfunction is an understudied yet important consideration in the treatment of schizophrenia. More attention is warranted in this area as it may provide opportunities for improved quality of life and adherence to treatment for patients.Keywords: sexual dysfunction, schizophrenia, hyperprolactinemia, antipsychotics, risperidone

  11. The Gay Men Sex Studies: prevalence of sexual dysfunctions in Belgian HIV+ gay men

    Directory of Open Access Journals (Sweden)

    Vansintejan J

    2013-04-01

    Full Text Available Johan Vansintejan, Joris Janssen, Erwin Van De Vijver, Jan Vandevoorde, Dirk Devroey Department of Family Medicine, Vrije Universiteit Brussel (VUB, Brussels, Belgium Abstract: The aim of this Internet-based survey was to investigate the prevalence and associated predictors of sexual dysfunctions in Belgian self-reported HIV-positive men who have sex with other men. Of the 72 participants, 56% had a mild-to-severe erectile dysfunction, and 15% reported a hypoactive sexual desire disorder. The prevalence of premature ejaculation and anodyspareunia was 18% for both. Independent predictors for erectile dysfunction were frequency of masturbation, frequency of sex with partner, use of erectile enhancement drugs, having a passive sex role, and not having a steady relationship. Independent predictors for hypoactive sexual desire disorder were frequency of masturbation and having a lower lifetime number of sexual partners. Independent predictors for premature ejaculation were not having a steady relationship, having a lower lifetime number of sexual partners, and a lower level of education. The only independent predictor for anodyspareunia was having an active sex role. Keywords: homosexuality/male, sexual dysfunction, HIV, epidemiology

  12. Retrograde ejaculation and sexual dysfunction in men with diabetes mellitus

    DEFF Research Database (Denmark)

    Fedder, J; Kaspersen, Maja Døvling; Brandslund, I;

    2013-01-01

    Retrograde ejaculation (RE) and erectile dysfunction may be caused by diabetes mellitus (DM), but the prevalence of RE among DM patients is unknown. A prospective, blinded case-control study comparing men with DM with matched controls according to RE and erectile dysfunction was performed. Twenty...

  13. Abordagem das disfunções sexuais femininas The assessment and management of female sexual dysfunction

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    Lúcia Alves da Silva Lara

    2008-06-01

    Full Text Available A disfunção sexual tem alta prevalência entre as mulheres. No entanto, os médicos raramente avaliam a vida sexual de suas pacientes, ou por se sentirem desconfortáveis em abordar a sexualidade ou porque desconhecem as técnicas de investigação. O modelo PILSET (PLISSIT, uma técnica de abordagem da função sexual humana, é composto por quatro elementos: permissão, informação limitada, sugestão específica e terapia sexual, que favorecem o diálogo entre o médico e a paciente, permitindo o acesso às queixas sexuais. A terapêutica consta de medidas de aconselhamento e orientações básicas sobre a função sexual, farmacoterapia e intervenções nos aspectos anátomo-funcionais do aparato sexual, com impacto positivo na vida sexual da mulher. Esta revisão mostra como usá-lo. Adicionalmente, vários aspectos da função sexual feminina, como prevalência, diagnóstico e outras modalidades de tratamento são discutidos.Sexual dysfunction prevalence is high among women. However, doctors rarely ask about their patients' sexual life, because they feel uncomfortable or because their knowledge about investigation techniques is insufficient. The PLISSIT model, a useful tool to access human sexual function, is composed by four elements: permission, limited information, specific suggestions, and intensive therapy, that favor dialogue between the doctor and the patient allowing the access to the sexual complaints. The therapeutics consists of counseling measures, drug prescription, basic orientations about sexual function and interventions on anatomic and functional aspects of the sexual apparatus with positive impact in the woman's sexual life. The present review shows how to use it. In addition, many aspects of female sexual dysfunction are discussed, such as prevalence, diagnostic and treatment options for female sexual dysfunction.

  14. In search of animal models for male sexual dysfunction

    NARCIS (Netherlands)

    Chan, J.S.W.

    2010-01-01

    Around half of all men have sexual problems. The main complaints and prevalence are orgasmic disorders (10%), premature ejaculation (PE) (27%), and erectile difficulties (10%). These statistics do not include the sexual side effects of medications such as antidepressants. Research experiments in hum

  15. A Multidisciplinary Approach to Sexual Dysfunction in Medical Education

    Science.gov (United States)

    Foley, Sallie; Wittmann, Daniela; Balon, Richard

    2010-01-01

    Objective: Addressing sexual health concerns in medical practice has been an emerging concept for the past two decades. However, there have been very few educational opportunities in medical training that would prepare future physicians for such a responsibility. Since assessing and treating sexual problems requires knowledge that encompasses many…

  16. Clinical Assessment of Tribulus terrestris Extract in the Treatment of Female Sexual Dysfunction

    OpenAIRE

    Carlos R.B. Gama; Ricardo Lasmar; Gama, Gustavo F; Abreu, Camila S; Nunes, Carlos P; Mauro Geller; Lisa Oliveira; Alessandra Santos

    2014-01-01

    This is a qualitative–quantitative study based on hospital records of female patients of reproductive age, presenting sexual dysfunction, and treated with 250 mg Tribulus terrestris extract (1 tablet thrice daily for 90 days). Safety monitoring included vital signs, physical examination, laboratory tests, and occurrence of adverse events. Efficacy analysis included results of the Female Sexual Function Index (FSFI), dehydroepiandrosterone (DHEA) levels together with total and free testosteron...

  17. Male gonadal function in coeliac disease: 1. Sexual dysfunction, infertility, and semen quality

    OpenAIRE

    Farthing, M J G; Edwards, C R W; Rees, L H; Dawson, A M

    1982-01-01

    The prevalence of hypogonadism, sexual dysfunction and abnormalities of semen quality was determined in 28 consecutive males with coeliac disease. These observations were related to jejunal morphology and nutritional status, and were compared with findings in 19 men with Crohn's disease of similar age and nutritional status. Two of the 28 coeliacs (7%) had clinical evidence of hypogonadism but impotence and decreased sexual activity occurred more commonly, the latter apparently improving afte...

  18. Incidence of sexual dysfunction in men after cardiac surgery in Afshar hospital, Yazd

    OpenAIRE

    Seyed Khalil Foruzan-Nia; Mohammad Hassan Abdollahi; Seyed Hossein Hekmatimoghaddam; Seyedeh Mahdiyeh Namayandeh; Mohammad Hadi Mortazavi

    2011-01-01

    Background: Successful rehabilitation of cardiac surgery patients should include consideration of their sexual activity, but there is paucity of data regarding this matter. Objective: This study determined the incidence and type of sexual dysfunction in our patients. Materials and Methods: Two hundred-seventy nine men with age under 70 years old who had coronary artery bypass graft (CABG), valvular, or other types of cardiac surgery from Dec. 2006 until Dec. 2007 were enrolled in this descrip...

  19. Co-relationship between sexual dysfunction and high-risk sexual behavior in patients receiving buprenorphine and naltrexone maintenance therapy for opioid dependence

    Directory of Open Access Journals (Sweden)

    Santosh Ramdurg

    2015-01-01

    Full Text Available Introduction: People suffering from substance dependence suffer from various sexual dysfunctions and are at risk for indulging in various high-risk sexual behaviors and thus are vulnerable to acquire various infections such as HIV/AIDS and other sexually transmitted infections. AIM: The aim of the study was to evaluate the correlation between sexual dysfunction and high-risk sexual behavior in opioid-dependent men receiving buprenorphine and naltrexone maintenance therapy. Materials and Methods: Semi-structured questionnaire, brief male sexual functioning inventory and HIV-risk taking behavior scale was administered to a sample of 60 sexually active men, receiving buprenorphine (n = 30 and naltrexone (n = 30 maintenance therapy for opioid dependence. Results: The main outcomes are correlation between severity of sexual dysfunction and HIV-risk taking behavior. The study results showed 83% of the men on buprenorphine and 90% on naltrexone reported at least one of the sexual dysfunction symptoms. There was a negative correlation between sexual dysfunction and HIV-risk taking behavior that suggest severe the dysfunction, higher the risk taking behavior. Significant correlation was present with overall sexual dysfunction and HIV-risk taking behavior (P = 0.028 and in naltrexone receiving group premature ejaculation versus HIV-risk taking behavior however, (P = 0.022, P < 0.05 there were no significant differences among both the groups except above findings. Conclusion: Conclusion was treatment is associated with sexual dysfunctions and HIV-risk taking behavior, which has clinical implication. Future research should explore this further using biochemical analyses.

  20. Is Internet Pornography Causing Sexual Dysfunctions? A Review with Clinical Reports.

    Science.gov (United States)

    Park, Brian Y; Wilson, Gary; Berger, Jonathan; Christman, Matthew; Reina, Bryn; Bishop, Frank; Klam, Warren P; Doan, Andrew P

    2016-01-01

    Traditional factors that once explained men's sexual difficulties appear insufficient to account for the sharp rise in erectile dysfunction, delayed ejaculation, decreased sexual satisfaction, and diminished libido during partnered sex in men under 40. This review (1) considers data from multiple domains, e.g., clinical, biological (addiction/urology), psychological (sexual conditioning), sociological; and (2) presents a series of clinical reports, all with the aim of proposing a possible direction for future research of this phenomenon. Alterations to the brain's motivational system are explored as a possible etiology underlying pornography-related sexual dysfunctions. This review also considers evidence that Internet pornography's unique properties (limitless novelty, potential for easy escalation to more extreme material, video format, etc.) may be potent enough to condition sexual arousal to aspects of Internet pornography use that do not readily transition to real-life partners, such that sex with desired partners may not register as meeting expectations and arousal declines. Clinical reports suggest that terminating Internet pornography use is sometimes sufficient to reverse negative effects, underscoring the need for extensive investigation using methodologies that have subjects remove the variable of Internet pornography use. In the interim, a simple diagnostic protocol for assessing patients with porn-induced sexual dysfunction is put forth. PMID:27527226

  1. Nature of Sexual Dysfunctions in Major Depressive Disorder and its Impact on Quality of Life

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    Rajarshi Guha Thakurta

    2012-01-01

    Full Text Available Background: Adequate sexual expression is an essential part of many human relationships, and may enhance quality of life and provide a sense of physical, psychological, and social well-being. Epidemiological and clinical studies show that depression is associated with impairments of sexual function and satisfaction, even in untreated patients. Most antidepressant drugs have adverse effects on sexual function, but accurate identification of the incidence of treatment-emergent dysfunction has proved troublesome. However, few investigators have reported the base rate for disturbances in sexual desire, arousal, and orgasm or ejaculation in patients with major depressive disorder (MDD prior to antidepressant treatment. The purpose of this study is to define the frequency of sexual dysfunction (SD in 60 patients with MDD and examine the relationship between SD and quality of life enjoyment and satisfaction variables. Materials and Methods: A consecutive series of 24 male and 36 female MDD patients diagnosed by SCID-DSM IV assessment completed a series of psychometric measures including a Sexual Function Questionnaire-Arizona Sexual Experience Scale (ASEX which asked about change in sexual interest and function as well as quality of life of life enjoyment using QLESQ-SF. Results: Over 33.33% of men and 42% of women reported decreased sexual interest. Reduced levels of arousal were more common in both men and women (8-22% than ejaculatory or orgasm difficulties (11-16%. In women, SDs were more than males. Quality of life was more impaired in sample with SDs than those without dysfunction showing significant impact of SD on quality of life. Limitation and Conclusion: Although limited by a relatively small sample of drug-free patients with MDD, and by the absence of a non-depressed comparison sample, these results emphasize the importance of factors beyond specific drug effects in the assessment of SD in drug naive-depressed patients.

  2.  The Effect of Amantadine on Clomipramine Induced Sexual Dysfunction in Male Rats

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    K Kumar Eswar

    2011-11-01

    Full Text Available  Objective: Several studies have reported that Clomipramine has the ability to suppress male rat sexual behavior. Literature indicatesthat the activation of brain D2 receptors causes facilitation of penile erection, and a number of reports have indicated dopamine’s involvement in sexual function. Hence this study was undertaken to investigate the effect of Amantadine, a dopamine agonists on the Clomipramine induced sexual dysfunction. Methods: The study subjects involved a total of 48 males and 48 females, 4 months old Sprague-Dawley albino rats, all housed in a group of six males and females separately in plexi glass cages in an acclimatized colony room (25±0.50C maintained on a 12/12 hr light/dark cycle. The male rats were randomly divided into four groups of 12 male rats each. Group I served as controls. Group II, III, and IV were treated with Amantadine (9 mg/kg body weight, p.o 30 min, prior to the treatment with 13.5 mg/kg, 27 mg/Kg and 54 mg/Kg bodyweight p.o of Clomipramine respectively for 60 days. The control group received vehicle 1 ml/kg p.o. The sexual behavior of the male rats was observed to determine the following parameters: mount latency, intromission latency, ejaculation latency, post ejaculatory pause, and intromission frequency. As well as the sexual behavior; serum testosterone and histopathology of the testes were also investigated in this study. Results: The results indicate that Amantadine in all aspects failed to antagonize Clomipramine induced sexual dysfunction in male rats. Even the sexual competence of male rats treated with 1/2 therapeutic dose (TD of Clomipramine failed to regain their sexual competence in the presence of Amantadine. Testicular damage and decline in testosterone levels continued in the presence of Amantadine. Conclusion: Overall, the results suggest that Amantadine could not be a safe antidote to antagonize Clomipramine induced sexual dysfunction.

  3. Female sexual dysfunction in patients with sub-stance-related disorders

    Directory of Open Access Journals (Sweden)

    Alessandra Diehl

    2013-01-01

    Full Text Available OBJECTIVE: To estimate the prevalence of female sexual dysfunction symptoms and the associated risk factors in a sample of patients with substance-related disorders admitted to a specialized in-patient care unit. METHODS: This study used a cross-section design, with eight months of data collection, conducted with substance-dependent women using structured questionnaires to collect socio-demographic data and identify their drug of choice. The Drug Abuse Screening Test, Short Alcohol Dependence Data questionnaire, Fagerstrom Test for Nicotine Dependence, and Arizona Sexual Experience Scale were also administered. RESULTS: The sample consisted of 105 women who had a mean age of 34.8 years (SD = 12.1, range = 18-65 and were predominantly heterosexual (74.3%, single (47.6%, Caucasian (50.5%, catholic (36.2%, and educated only to the level of primary education (40%, with a monthly family income of up to one minimum salary (37.5%. In 42.9% of the patients, crack was the drug of choice; 47.6% of the sample qualified for the Drug Abuse Screening Test (substantial problems related to drugs, 43.8% exhibited Short Alcohol Dependence Data (moderate or severe dependency, 47.6% exhibited Fagerstrom Test for Nicotine Dependence (high or very high nicotine dependence. The prevalence of sexual dysfunction symptoms was 34.2% (95% CI = [25.3, 44.1], and a high level of nicotine dependence and low income increased the chances of having sexual dysfunction by 2.72-fold and 2.54 fold, respectively. An association was also observed between female sexual dysfunction symptoms and schooling and levels of drug dependence. CONCLUSIONS: Female sexual dysfunction symptoms were common among this sample and primarily associated with high levels of nicotine use.

  4. Successful Use of Add - On Topiramate for Antipsychotic - Induced Weight Gain

    OpenAIRE

    Venkataram Shivakumar; Naveen Jayaram; Rao, Naren P.; Ganesan Venkatasubramanian

    2012-01-01

    Antipsychotic induced weight gain is the most common and distressing side effect. This also affects the compliance toward the treatment and hence the prognosis. Non - pharmacological interventions such as exercise and diet modifications alone might not be sufficient most of the times; also ensuring compliance toward this is difficult in patients with psychiatric illness. So, the role of weight - reducing drugs become important. In this case report, we describe the use of low - dose topiramate...

  5. Male gonadal function in coeliac disease: 1. Sexual dysfunction, infertility, and semen quality.

    Science.gov (United States)

    Farthing, M J; Edwards, C R; Rees, L H; Dawson, A M

    1982-07-01

    The prevalence of hypogonadism, sexual dysfunction and abnormalities of semen quality was determined in 28 consecutive males with coeliac disease. These observations were related to jejunal morphology and nutritional status, and were compared with findings in 19 men with Crohn's disease of similar age and nutritional status. Two of the 28 coeliacs (7%) had clinical evidence of hypogonadism but impotence and decreased sexual activity occurred more commonly, the latter apparently improving after gluten withdrawal. Of the married coeliacs, 19% had infertile marriages, a value greater than expected in the general population. Hypogonadism and sexual dysfunction were not detected in our patients with Crohn's disease. Seminal analysis in coeliacs revealed marked abnormalities of sperm morphology and motility, but only the former appeared to improve after gluten withdrawal. Similar abnormalities, however, were also detected in patients with Crohn's disease, although, unlike the coeliacs, 46% also had reduced concentrations of spermatozoa. Semen quality in coeliac disease could not be clearly related to general or specific (serum vitamin B(12) and red cell folate) nutritional deficiencies or to fertility, although sperm motility was markedly reduced in two of the three coeliacs with infertile marriages. The presence of antisperm antibodies did not appear to be an important aetiological factor in male infertility in coeliac disease. The pathogenesis of infertility and sexual dysfunction in coeliac disease remains unclear, suggesting that factors such as endocrine dysfunction or other specific nutritional deficiency may be involved. PMID:7200931

  6. Long-term anorectal, urinary and sexual dysfunction causing distress after radiotherapy for anal cancer

    DEFF Research Database (Denmark)

    Sunesen, K G; Nørgaard, M; Lundby, L;

    2015-01-01

    AIM: The objective of primary radiotherapy for anal cancer is to remove cancer while maintaining anorectal function. However, little is known about anorectal function among long-term survivors without colostomy. Using a cross-sectional questionnaire study, we examined symptoms and distress relate...... function. CONCLUSION: Distressing long-term anorectal and sexual dysfunction was common after radiotherapy for anal cancer, and morbidity due to urinary dysfunction was moderate.......AIM: The objective of primary radiotherapy for anal cancer is to remove cancer while maintaining anorectal function. However, little is known about anorectal function among long-term survivors without colostomy. Using a cross-sectional questionnaire study, we examined symptoms and distress related...... to the dysfunction of pelvic organs after radiotherapy for anal cancer. METHOD: A questionnaire regarding anorectal, urinary and sexual symptoms was sent to anal cancer patients without recurrence or colostomy, diagnosed during 1996-2003, and treated with curative intent (chemo)radiotherapy at three Danish centres...

  7. [Cognitive-behavioural therapy for sexual dysfunctions: treatment, etiology and accurate diagnosing of premature ejaculation].

    Science.gov (United States)

    Rawińska, Marta; Fijałkowska, Sylwia

    2014-01-01

    Premature ejaculation (PE) is one of the most common male sexual dysfunctions. Successful treatment of PE has been hampered by the existence of a variety of definitions and diagnostic criteria and the lack of large, long-term studies of treatment efficacy. Numerous, diverse treatment approaches with varying degrees of efficacy have been used; these include behavioral, cognitive, and sex therapy techniques, and pharmacologic management with antidepressants, phosphodiesterase-5 inhibitors, and topical anesthetics. Combining a specific pharmacologic treatment for premature ejaculation with appropriate cognitive, behavioral, and sex therapy techniques should improve the overall understanding and management of sexual dysfunction, resulting in a sustainable increase in sexual satisfaction and decrease in distress for man. The aim of this article is to raise awareness of the prevalence of PE, its symptoms, and the impact it has on both partners and to discuss the benefits of adding limited behavioral and cognitive sex therapy techniques to drug therapy. PMID:24645584

  8. A field trial of the effectiveness of behavioral treatment for sexual dysfunctions.

    Science.gov (United States)

    Sarwer, D B; Durlak, J A

    1997-01-01

    The present study was a field trial of behavioral sex therapy for 365 married couples presenting with a range of sexual dysfunctions. Treatment occurred at an outpatient sexual dysfunction clinic of a large medical center using a multidisciplinary staff. Findings supported the external validity of behavioral sex therapy. The success rate for the total sample (65%) was comparable to that of previous investigations, and there were very few dropouts (1.6%) from treatment. In addition, outcomes did not vary significantly as a function of diagnoses, gender, or a history of sexual abuse. The amount of sensate focus completed in the last week of treatment was the strongest predictor of successful treatment. For some diagnoses, however, couple comorbidity reduced treatment success. Results indicated that behavioral sex therapy is effective in real-world clinical settings. PMID:9230489

  9. COMT Val158Met Polymorphism, Executive Dysfunction, and Sexual Risk Behavior in the Context of HIV Infection and Methamphetamine Dependence

    OpenAIRE

    Bousman, C. A.; Cherner, M.; Atkinson, J.H.; Heaton, R. K.; GRANT, I.; Everall, I. P.; The HNRC Group

    2010-01-01

    Catechol-O-methyltransferease (COMT) metabolizes prefrontal cortex dopamine (DA), a neurotransmitter involved in executive behavior; the Val158Met genotype has been linked to executive dysfunction, which might increase sexual risk behaviors favoring HIV transmission. Main and interaction effects of COMT genotype and executive functioning on sexual risk behavior were examined. 192 sexually active nonmonogamous men completed a sexual behavior questionnaire, executive functioning tests, and were...

  10. Sexual Dysfunction, Depression and Quality of Life in Patients With HIV Infection

    Science.gov (United States)

    Amini Lari, Mahmood; Faramarzi, Hosain; Shams, Mesbah; Marzban, Maryam; Joulaei, Hasan

    2013-01-01

    Objective: In Iran, psychological aspect of HIV infection is poorly understood. The purposes of this study were to evaluate sexual dysfunction, depression rate and health-related quality of life and evaluate the association between sexual dysfunction, depression and quality of life in a group of HIV+ subjects in Shiraz, Iran. Methods: In this cross-sectional study, 278 male HIV-positive patients who had referred to voluntary counseling and testing and methadone maintenance therapy centers were recruited based on convenience sampling from May to October 2010. The purpose of the study was explained and interested individuals provided informed consent and completed validated questionnaires [Medical Outcomes Study Short Form-36 (SF-36(, Brief Male Sexual Function Inventory (BMSFI), Beck Depression Inventory-short form(BDI)] to assess overall health related quality of life (HRQOL), sexual function, and depression. Results: Average age of the participants was 34.9 ± 10.7 years and 37.5% were severely depressed. Ordinal logistic regression indicated that sexual drive (-0.15; CI: -0.28 to -0.027), ejaculation (-1.91, CI: -2.71 to -1.12), and problem assessment (-0.098, CI: -0.17 to -0.02) had significant effect on depression type. Depression was significantly correlated with poorer quality of life in all domains. Pearson’s correlation coefficients between the BMSFI and the domains of SF-36 indicated that sexual drive (r= 0.215), ejaculation (r= 0.297) and problem assessment (r= 0.213) were significantly correlated with emotional wellbeing. Conclusion: Sexual function and depression showed association with quality of life. Effective treatment of depression and sexual function may improve the quality of life of HIV-infected person. Declaration of interest: None. PMID:24644501

  11. Sweet Bee Venom Pharmacopuncture May be Effective for Treating Sexual Dysfunction

    Directory of Open Access Journals (Sweden)

    Pavel Lee

    2014-09-01

    Full Text Available Sexual dysfunction (SD is a health problem which occurs during any phase of the sexual response cycle that keeps the individual or couple from experiencing satisfaction from the sexual activity. SD covers a wide variety of symptoms like in men, erectile dysfunction and premature or delayed ejaculation, in women, spasms of the vagina and pain with sexual intercourse, in both sexes, sexual desire and response. And pharmacopuncture, i.e. injection of subclinical doses of drugs, mostly herb medicine, in acupoints, has been adopted with successful results. This case report showed the effect of bee venom on SD. A 51-year-old male patient with SD, who had a past history of taking Western medication to treat his SD and who had previously undergone surgery on his lower back due to a herniated disc, received treatments using pharmacopuncture of sweet bee venom (SBV at Gwanwon (CV4, Hoeeum (CV1, Sinsu (BL23, and Gihaesu (BL24 for 20 days. Objectively, the patient showed improvement on most items on the International Index for Erectile Dysfunction (IIEF like 28 to 29 out of perfect score 30 for erectile function, 10 to 10 out of perfect score 10 for orgasmic function, 6 to 8 out of perfect score 10 for sexual desire, 10 to 13 out of perfect score 15 for satisfaction with intercourse, and 6 to 8 out of perfect score 10 for overall satisfaction; subjectively, his words, the tone of his voice and the look of confidence in his eyes all indicated improvement. Among the variety of effects of SBV pharmacopuncture, urogenital problems such as SD may be health problems that pharmacopuncture can treat effectively.

  12. Sexual dysfunction in married female patients with anorexia and bulimia nervosa.

    Science.gov (United States)

    Simpson, W S; Ramberg, J A

    1992-01-01

    The immediacy of anorexia and bulimia nervosa tends to obscure the adjunct problems of eating-disordered patients. The literature records no data pertaining to the treatment of concomitant psychosexual dysfunctions. The authors report the cases of five young married women referred for psychosexual therapy from eating disorders programs. The therapists found that each of the women was suffering from at least one additional disorder. Basic issues of control, grounded in these patients' early lives, generated intense resistance to treatment. The authors emphasize the need for accelerated research to gather the data from which to develop an effective treatment program for eating-disordered patients with associated sexual dysfunctioning. PMID:1556757

  13. Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction.

    Science.gov (United States)

    Wikberg, Jarl E S; Mutulis, Felikss

    2008-04-01

    The melanocortin system has multifaceted roles in the control of body weight homeostasis, sexual behaviour and autonomic functions, and so targeting this pathway has immense promise for drug discovery across multiple therapeutic areas. In this Review, we first outline the physiological roles of the melanocortin system, then discuss the potential of targeting melanocortin receptors by using MC3 and MC4 agonists for treating weight disorders and sexual dysfunction, and MC4 antagonists to treat anorectic and cachectic conditions. Given the complexity of the melanocortin system, we also highlight the challenges and opportunities for future drug discovery in this area. PMID:18323849

  14. Sexual Dysfunction and Hyperprolactinemia in Male Psychotic Inpatients: A Cross-Sectional Study

    Directory of Open Access Journals (Sweden)

    Erik Johnsen

    2011-01-01

    Full Text Available Introduction. Sexual dysfunction (SD and hyperprolactinemia are frequently reported in patients with psychotic disorders and have the potential for severe complications but investigations in males are particularly scarce. The primary aims were to determine the prevalence of SD and hyperprolactinemia in male patients and to investigate whether associations exist between SD and prolactin levels. Methods. Cross-sectional data were obtained at discharge from the hospital or 6 weeks after admittance for patients acutely admitted for psychosis and treated with a second-generation antipsychotic drug. Results. Half the patients reported diminished sexual desire and more than a third reported erectile and ejaculatory dysfunctions with no differences among the drugs. More than half the sample was hyperprolactinemic. No association was found between prolactin levels and SD. Conclusion. High rates of SD and hyperprolactinemia were found in male patients and should be a treatment target. SD and hyperprolactinemia were not correlated.

  15. Adjunctive aripiprazole versus placebo for antipsychotic-induced hyperprolactinemia: meta-analysis of randomized controlled trials.

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    Xianbin Li

    Full Text Available OBJECTIVE: To compare the safety and efficacy of adjunctive aripiprazole versus placebo for antipsychotic-induced hyperprolactinemia. METHODS: POPULATION: adult patients presenting with antipsychotic-induced hyperprolactinemia diagnosed by prolactin level with or without prolactin-related symptoms. INTERVENTIONS: adjunctive aripiprazole vs. adjunctive placebo. OUTCOME MEASURES: adverse events and efficacy of treatment. STUDIES: randomized controlled trials. RESULTS: Five randomized controlled trials with a total of 639 patients (326 adjunctive aripiprazole, 313 adjunctive placebo met the inclusion criteria. Adjunctive aripiprazole was associated with a 79.11% (125/158 prolactin level normalization rate. Meta-analysis of insomnia, headache, sedation, psychiatric disorder, extrapyramidal symptom, dry mouth, and fatigue showed no significant differences in the adjunctive aripiprazole treatment group compared with the placebo group (risk difference (Mantel-Haenszel, random or fixed -0.05 to 0.04 (95% confidence interval -0.13 to 0.16; I(2 =0% to 68%, P=0.20 to 0.70. However, sedation, insomnia, and headache were more frequent when the adjunctive aripiprazole dose was higher than 15 mg/day. Meta-analysis of the prolactin level normalization indicated adjunctive aripiprazole was superior to placebo (risk difference (Mantel-Haenszel, random 0.76 (95% confidence interval 0.67 to 0.85; I(2 =43%, P<0.00001. The subgroup analysis confirmed that the subjects who received adjunctive aripiprazole 5 mg/day showed a degree of prolactin normalization similar to that of all participants. No significant differences between groups in discontinuation and improvements of psychiatric symptoms. CONCLUSION: Adjunctive aripiprazole is both safe and effective as a reasonable choice treatment for patients with antipsychotic-induced hyperprolactinemia. The appropriate dose of adjunctive aripiprazole may be 5 mg/day.

  16. Female sexual dysfunction in patients with sub-stance-related disorders

    OpenAIRE

    Alessandra Diehl; Rosiane Lopes da Silva; Ronaldo Laranjeira

    2013-01-01

    OBJECTIVE: To estimate the prevalence of female sexual dysfunction symptoms and the associated risk factors in a sample of patients with substance-related disorders admitted to a specialized in-patient care unit. METHODS: This study used a cross-section design, with eight months of data collection, conducted with substance-dependent women using structured questionnaires to collect socio-demographic data and identify their drug of choice. The Drug Abuse Screening Test, Short Alcohol Dependence...

  17. Sexual Dysfunction and Hyperprolactinemia in Male Psychotic Inpatients: A Cross-Sectional Study

    OpenAIRE

    Hugo A. Jørgensen; Else-Marie Løberg; Erik Johnsen; Rune Kroken; Eirik Kjelby

    2011-01-01

    Introduction. Sexual dysfunction (SD) and hyperprolactinemia are frequently reported in patients with psychotic disorders and have the potential for severe complications but investigations in males are particularly scarce. The primary aims were to determine the prevalence of SD and hyperprolactinemia in male patients and to investigate whether associations exist between SD and prolactin levels. Methods. Cross-sectional data were obtained at discharge from the hospital or 6 weeks after admitta...

  18. Successful Use of Add - On Topiramate for Antipsychotic - Induced Weight Gain

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    Venkataram Shivakumar

    2012-01-01

    Full Text Available Antipsychotic induced weight gain is the most common and distressing side effect. This also affects the compliance toward the treatment and hence the prognosis. Non - pharmacological interventions such as exercise and diet modifications alone might not be sufficient most of the times; also ensuring compliance toward this is difficult in patients with psychiatric illness. So, the role of weight - reducing drugs become important. In this case report, we describe the use of low - dose topiramate as a weight - reducing agent, in a patient with a bipolar affective disorder - mania with psychotic symptoms, who had significant risperidone - induced weight gain.

  19. Sexual dysfunction with the use of antidepressants in a tertiary care mental health setting - a retrospective case series

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    Kingshuk Lahon

    2011-01-01

    Full Text Available Sexual dysfunction affects patients′ quality of life. It can occur secondary to physical or mental disorders, substance abuse and treatment with prescription drugs like antidepressants. We wanted to study the prevalence of sexual dysfunction associated with antidepressant use in the psychiatric unit of a tertiary care hospital and assess for causality, severity and preventability. We did a retrospective data collection from case records of patients on antidepressants from the Psychiatry outpatient clinic of a tertiary care teaching hospital during the period 1 st January 2006 to 31 st December 2006, excluding those with complaints of sexual dysfunction prior to treatment. Data are presented as a case series. Documented adverse events were subjected to analysis for causality, severity and preventability using Naranjo′s, modified Hartwig and Siegel and modified Schumock and Thornton′s Preventability scales respectively. Out of 169 patients, four patients developed sexual dysfunction (2.36% associated with duloxetine, mirtazapine, trazodone and sertraline. We observed a possible causal relationship of mild to moderately severe ADR (sexual dysfunction which was not preventable. Prevalence of antidepressant associated sexual dysfunction was lower than quoted in Western literature probably due to the retrospective nature of our study design. Active monitoring and intervention can greatly improve the quality of life and compliance to treatment.

  20. Determinants of sexual dysfunction in male and female patients with parkinson’s disease

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    murat ilhan atagun

    2013-01-01

    Full Text Available Objective: Due to the complex nature of Parkinson’s disease (PD and distinct sexual physiologies, male and female patients might have different patterns of sexual dysfunction (SD in PD. The aim of this study was to assess determinants of SD in female and male patients with PD. Methods: Seventy nine outpatients with idiopathic PD (46 male, 33 female; mean age: 67.51±8.27 were recruited between December 2007 and February 2011. Unified Parkinson’s Disease Rating Scale and Hoehn–Yahr stages, Hamilton depression and anxiety scales, Mini-Mental State Examination and Arizona Sexual Experiences scale were the measures. Results: Determinants of SD in the whole group were age and anxiety. Age at disease onset and anxiety designated SD in female group, while age and severity of motor symptoms designated SD in male group. Conclusion: Both in males and females, gonadal steroids decline with advancing age. Dopamine has role in desire, erection, reward-seeking behavior phases of sexuality. Dopamine depletion may cause SD with its dual effects, including erectile dysfunction as well as motor disturbances in PD in male patients. Anxiety effect females more than males due to affected body image and perception of the self.

  1. Influence of sexual performance anxiety on Erectile Dysfunction%性操作焦虑对阴茎勃起障碍的影响研究

    Institute of Scientific and Technical Information of China (English)

    刘明矾

    2002-01-01

    Objective: To understand psychological factors involved in erectile dysfunction. Methods: The erectile dysfunction rating scale (EDRS), State-trait anxiety inventory (STAI), and sexual psychological questionnaire (self-designed) were administered to 74 cases (30 psychogenic ED patients and 44 normal control objects).Results: High levels of sexual performance anxiety were found to affect patients' self-evaluation and coping responses. Sexual performance anxiety, deficient sexual sensitivity and poor communication techniques were the major contributing factors of psychogenic erectile dysfunction.Conclusion: Sexual performance anxiety constitutes a significant factor of erective dysfunction.

  2. Historical and Current Factors Discriminating Sexually Functional from Sexually Dysfunctional Married Couples.

    Science.gov (United States)

    Heiman, Julia R.; And Others

    1986-01-01

    Compared clinical couples accepted for sex therapy with nonclinical couples using the Personal History Questionnaire and sex and marital defensiveness scales. The best discriminators were sexual functioning scales, historical and affective scales for women, and current and fantasy scales for men. Surprising results and conclusions are discussed.…

  3. Antipsychotic-induced extrapyramidal syndromes and cytochrome P-450 2D6 genotype : a case-control study

    NARCIS (Netherlands)

    Schillevoort, [No Value; de Boer, A; van der Weide, J; Steijns, LSW; Roos, RAC; Jansen, PAF; Leufkens, HGM

    2002-01-01

    To study the association between polymorphism of the cytochrome P-450 2D6 gene (CYP2D6) and the risk of antipsychotic-induced extrapyramidal syndromes, as measured by the use of anti parkinsonian medication. Data for this case-control study were obtained from a psychiatric hospital where newly admit

  4. Determinants of sexual dysfunction and interventions for patients with obstructive sleep apnoea

    DEFF Research Database (Denmark)

    Steinke, E; Palm Johansen, P; Fridlund, B;

    2016-01-01

    AIMS: Obstructive sleep apnoea (OSA) may negatively affect a couple's sexual relationship. This systematic review evaluated what characteristics are determinants of sexual function and dysfunction in women and men with OSA, and what interventions are shown to be effective. METHODS: A systematic...... literature review was conducted using PubMed, CINAHL, Cochrane and TRIP, and articles published between January 2004 and December 2014 in English; original research; adults ≥ 18 years; and both experimental and non-experimental designs. The Effective Public Health Practice Project Quality Assessment Tool for...... Quantitative Studies was used to assess study quality. Of 21 studies, six studies (no randomised control trials, RCTs) included women and 15 (with six RCTs) studies included men. Extracted data were scrutinised and adjusted until consensus was reached; suitable quantitative data were pooled in statistical meta...

  5. The effect of male erectile dysfunction on the psychosocial, relationship, and sexual characteristics of heterosexual women in the United States.

    Science.gov (United States)

    Cameron, Ann; Tomlin, Molly

    2007-01-01

    Using Internet-based survey data, this study compared the demographic, psychosocial, relationship, and sexual characteristics of three groups of U.S. women: (a) women whose partners had erectile dysfunction (ED) and were taking medication to treat ED; (b) women whose partners had ED in the previous 3 months and were not taking medication to treat ED; and (c) a control group of women whose partners did not have ED. Results indicate that women are affected by their partners' ED and that ED treatment benefits women's sexual self-efficacy, communication about sexual issues, and sexual and relationship satisfaction. PMID:17365514

  6. Epidemiology of Sexual Dysfunction in Iran: A Systematic Review and Meta-analysis

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    Mohammad Arash Ramezani

    2015-01-01

    Full Text Available Background: The aim of this study was to determine the cumulative prevalence rate of every sexual dysfunctions (SDs in Iranian population. Methods: We searched international database such as: PubMed/Medline, Scopus, PsychNET, and Scholar Google and Iranian database such as Iran Psych, IranDoc, IranMedex, and SID. Search duration was between 1990 and 2013. Results: From 449 articles were retrieved, then 11 articles on male with total sample size of 2142 and 8 articles on female with total sample size of 4391 were selected after critical appraisal. For quality assessment check list to evaluate a prevalence article was contained study population, sampling method, sample size, criteria for SD diagnosis, specific rates, study location, and authors list. In male, erectile dysfunction was 56.1%. In female, pooled estimation prevalence of hypoactive sexual desire disorder in complained group was 65.8% (95% confidence interval [CI]: 51.1-80.6% compared to general population 35% (95% CI: 17.6-52.1%. Sexual arousal disorder in clinical patient was 59.6% (95% CI: 39-80% against 33.8% (95% CI: 18.3-49.3% in general population. Orgasmic disorder in complained was 35.5% (95% CI: 16-55% and in general population was 35.3% (95% CI: 26.8-43.8%. Sexual pain disorder pooled estimation prevalence were 35.2% (95% CI: 14.5-56% versus 20.1% (95% CI: 6.4-33.8% in complained and general population consecutively. Conclusions: The rate of SD in Iran was approximately the same of worldwide except orgasmic disorder which was two times more than the worldwide average.

  7. Depression and sexual dysfunction in chronic kidney disease: a narrative review of the evidence in areas of significant unmet need.

    Science.gov (United States)

    Vecchio, Mariacristina; Palmer, Suetonia C; Tonelli, Marcello; Johnson, David W; Strippoli, Giovanni F M

    2012-09-01

    People with chronic kidney disease (CKD) have a high symptom burden and experience poorer quality of life than the general population. People with CKD frequently report fatigue, anorexia, pain, sleep disturbance, itching and restless legs. Depression and sexual dysfunction may also be common in CKD, although questions about optimal diagnosis and treatment remain unanswered. People with kidney disease identify lifestyle and the impact of CKD on family and psychosocial supports as key priorities and rate symptoms such as sexual dysfunction and psychological distress as severe. Here, we outline the current state of research underlying depression and sexual dysfunction in this population focusing on prevalence, diagnosis, screening, outcomes and interventions and suggest areas requiring additional specific research. PMID:22942174

  8. Does Bicycle Riding Impact the Development of Lower Urinary Tract Symptoms and Sexual Dysfunction in Men?

    Science.gov (United States)

    Kim, Dong Gon; Kim, Dae Woong

    2011-01-01

    Purpose This study was designed to determine whether men who engaged in recreational bicycle riding are more likely to be affected by lower urinary tract symptoms (LUTS) and sexual dysfunction than are man who exercised by amateur marathon running with less perineal impact. Materials and Methods A total of 22 healthy male amateur bicyclists and 17 healthy male amateur marathoners were enrolled in the study. We evaluated questionnaires including the International Prostate Symptom Score (IPSS) and the International Index of Erectile Function (IIEF), serum prostate-specific antigen (PSA), uroflowmetric values, postvoid residual (PVR) urine volume, and transrectal ultrasound of the prostate in all subjects. We also compared the prevalence of urination disorders (UD) and erectile dysfunction (ED). Results There were no significant differences between the two groups in age, body mass index, comorbidities, or exercise habits (p>0.05). Mean total and subscale scores of the IPSS and IIEF and the prevalence of UD (8/22 vs. 4/17, p=0.494) and ED (11/22 vs. 10/17, p=0.748) were not significantly different between the two groups. Also, there were no significant differences between the two groups in uroflowmetric parameters such as peak urinary flow rates, voided urine volume, PVR urine volume, prostate volume, or serum PSA level. Conclusions Bicycle riding seems to have no measurable hazardous effect on voiding function or sexual function in men who cycled recreationally. PMID:21687396

  9. Sexual dysfunction, mood, anxiety, and personality disorders in female patients with fibromyalgia

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    Kayhan F

    2016-02-01

    Full Text Available Fatih Kayhan,1 Adem Küçük,2 Yılmaz Satan,3 Erdem İlgün,4 Şevket Arslan,5 Faik İlik6 1Department of Psychiatry, Faculty of Medicine, Selçuk University, 2Department of Rheumatology, Faculty of Medicine, Necmettin Erbakan University, 3Department of Psychiatry, Konya Numune State Hospital, 4Department of Physical Therapy and Rehabilitation, Faculty of Medicine, Mevlana University, 5Department of Internal Medicine, Faculty of Medicine, Necmettin Erbakan University, 6Department of Neurology, Faculty of Medicine, Başkent University, Konya, Turkey Background: We aimed to investigate the current prevalence of sexual dysfunction (SD, mood, anxiety, and personality disorders in female patients with fibromyalgia (FM.  Methods: This case–control study involved 96 patients with FM and 94 healthy women. The SD diagnosis was based on a psychiatric interview in accordance with the Diagnostic and Statistical Manual of Mental Disorders, fourth edition criteria. Mood and anxiety disorders were diagnosed using the Structured Clinical Interview. Personality disorders were diagnosed according to the Structured Clinical Interview for DSM, Revised Third Edition Personality Disorders.  Results: Fifty of the 96 patients (52.1% suffered from SD. The most common SD was lack of sexual desire (n=36, 37.5% and arousal disorder (n=10, 10.4%. Of the 96 patients, 45 (46.9% had a mood or anxiety disorder and 13 (13.5% had a personality disorder. The most common mood, anxiety, and personality disorders were major depression (26%, generalized anxiety disorder (8.3%, and histrionic personality disorder (10.4%.  Conclusion: SD, mood, and anxiety disorders are frequently observed in female patients with FM. Pain plays a greater role in the development of SD in female patients with FM. Keywords: anxiety, depression, fibromyalgia, sexual dysfunction

  10. Sexual dysfunction in testicular cancer patients subjected to post-chemotherapy retroperitoneal lymph node dissection: a focus beyond ejaculation disorders.

    Science.gov (United States)

    Dimitropoulos, K; Karatzas, A; Papandreou, C; Daliani, D; Zachos, I; Pisters, L L; Tzortzis, V

    2016-05-01

    Post-chemotherapy retroperitoneal lymph node dissection (PC-RPLND) represents an integral part of multidisciplinary treatment of advanced germ cell cancer; however, it is associated with a high complications rate. The present study aimed to describe sexual disorders in 53 patients with testicular cancer who underwent full bilateral, non-nerve-sparing PC-RPLND in our institution, focusing beyond ejaculatory dysfunction. The International Index for Erectile Function (IIEF) questionnaire was used as diagnostic tool of male sexual functioning pre-operatively and three months after RPLND, while post-operatively patients were asked to describe and evaluate changes in selected sexual parameters. Study findings demonstrate mixed pattern of changes in sexual functioning, with no difference in erectile functioning before and after operation. However, orgasmic function and intercourse and overall sexual satisfaction were found significantly impaired post-operatively. Sexual desire and frequency of attempted sexual intercourses were found significantly increased post-operatively, in comparison with pre-operative levels. With regard to patients' subjective perception on sexual functioning alterations after PC-RPLND, a significant number of patients reported higher levels of sexual desire, no difference in erectile function and worse orgasmic function and satisfaction post-operatively. Thus, patients subjected to PC-RPLND should be closely and routinely evaluated due to close relationship of sexual dissatisfaction with secondary psychological disorders. PMID:26268684

  11. Pharmacogenetics of antipsychotic-induced movement disorders as a resource for better understanding Parkinson's disease modifier genes

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    Lior eGreenbaum

    2015-02-01

    Full Text Available Antipsychotic-induced movement disorders are major side effects of antipsychotic drugs among schizophrenia patients, and include antipsychotic-induced parkinsonism (AIP and tardive dyskinesia (TD. Substantial pharmacogenetic work has been done in this field, and several susceptibility variants have been suggested. In this paper, the genetics of antipsychotic-induced movement disorders is considered in a broader context. We hypothesize that genetic variants that are risk factors for AIP and TD may provide insights into the pathophysiology of Parkinson's disease (PD. Since loss of dopaminergic stimulation (albeit pharmacological in AIP and degenerative in PD is shared by the two clinical entities, genes associated with susceptibility to AIP may be modifier genes that influence clinical expression of PD sub-phenotypes, such as age at onset, disease severity or rate of progression. This is due to their possible functional influence on compensatory mechanisms for striatal dopamine loss. Better compensatory potential might be beneficial at the early and later stages of the PD course. AIP vulnerability variants may also be related to latent impairment in the nigrostriatal pathway, affecting its functionality, and leading to subclinical dopaminergic deficits in the striatum. Susceptibility of PD patients to early development of L-dopa induced dyskinesia (LID, is an additional relevant sub-phenotype. LID may share a common genetic background with TD, with which it shares clinical features. Genetic risk variants may predispose to both phenotypes, exerting a pleiotropic effect. According to this hypothesis, elucidating the genetics of antipsychotic-induced movement disorders may advance our understanding of multiple aspects of PD and it clinical course, rendering this a potentially rewarding field of study.

  12. Genome-wide association study on antipsychotic-induced weight gain in the CATIE sample.

    Science.gov (United States)

    Brandl, E J; Tiwari, A K; Zai, C C; Nurmi, E L; Chowdhury, N I; Arenovich, T; Sanches, M; Goncalves, V F; Shen, J J; Lieberman, J A; Meltzer, H Y; Kennedy, J L; Müller, D J

    2016-08-01

    Antipsychotic-induced weight gain (AIWG) is a common side effect with a high genetic contribution. We reanalyzed genome-wide association study (GWAS) data from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) selecting a refined subset of patients most suitable for AIWG studies. The final GWAS was conducted in N=189 individuals. The top polymorphisms were analyzed in a second cohort of N=86 patients. None of the single-nucleotide polymorphisms was significant at the genome-wide threshold of 5x10(-8). We observed interesting trends for rs9346455 (P=6.49x10(-6)) upstream of OGFRL1, the intergenic variants rs7336345 (P=1.31 × 10(-5)) and rs1012650 (P=1.47 × 10(-5)), and rs1059778 (P=1.49x10(-5)) in IBA57. In the second cohort, rs9346455 showed significant association with AIWG (P=0.005). The combined meta-analysis P-value for rs9346455 was 1.09 × 10(-7). Our reanalysis of the CATIE GWAS data revealed interesting new variants associated with AIWG. As the functional relevance of these polymorphisms is yet to be determined, further studies are needed.The Pharmacogenomics Journal advance online publication, 1 September 2015; doi:10.1038/tpj.2015.59. PMID:26323598

  13. Quality of life among women with sexual dysfunction undergoing hemodialysis: a cross-sectional observational study

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    Santos Paulo

    2012-08-01

    Full Text Available Abstract Background Sexual function among women undergoing hemodialysis (HD is under-studied and there is no consensus about the effect of sexual dysfunction (SD on their quality of life (QoL. We aimed to determine the prevalence of SD and to compare QoL between women undergoing maintenance HD with and without SD. Methods We included female end-stage renal disease (ESRD patients undergoing HD during June 2011 in the only renal unit in the north of Ceará state, northeastern Brazil. The criteria for inclusion were age between 18 and 55, at least three months on dialysis and being sexually active. Women using antidepressant medication were excluded. We used the Female Sexual Function Index (FSFI, which evaluates six domains of sexual function, including desire, arousal, lubrication, orgasm, satisfaction and pain. The patients were classified as presenting SD if the total FSFI score was less than 26. For QoL evaluation, we used the validated Brazilian version of SF-36. This is a widely used 36-item questionnaire covering eight dimensions of QoL. Demographic data, time on dialysis, underlying etiology of ESRD, and laboratory measures were assessed in unit records. Results Of a total of 58 women, 46 (79.3% presented SD. There were lower scores related to physical functioning (48.2 vs. 71.2; p = 0.007, bodily pain (45 vs. 67.5; p = 0.010, vitality (52.1 vs. 69.1; p = 0.026 and social functioning (57.2 vs. 76.1; p = 0.034 among women with SD compared to women without SD. Physical functioning and role-physical presented positive linear correlation with FSFI scores, respectively, r = 0.322 (p = 0.013 and r = 0.345 (p = 0.007. Conclusion The prevalence of SD among women on HD is very high, reaching nearly 80%. Women on HD with SD had worse QoL, especially physical aspects of QoL, when compared to women without SD. Therefore, approaches aiming to improve QoL among women undergoing HD should be considered.

  14. Orgasmic dysfunction

    Science.gov (United States)

    Inhibited sexual excitement; Sex - orgasmic dysfunction; Anorgasmia ... GM. Emotional aspects of gynecology: depression, anxiety PTSD, eating disorders, substance abuse, "difficult" patients, sexual function, rape intimate partner violence, and grief. In: ...

  15. Electroencephalographic activity during sexual behavior: a novel approach to the analysis of drug effects on arousal and motivation relevant for sexual dysfunctions.

    Science.gov (United States)

    Hernández-González, Marisela; Guevara, Miguel Angel; Agmo, Anders

    2014-06-01

    The neurobiological bases of human sexual behavior are only partly understood. The etiology of most human sexual dysfunctions is not understood at all. Nevertheless, substantial progress has been made in the treatment of some male sexual disorders. The prime example should be erectile deficiency, where several efficient and safe treatments are available. Pharmacological treatment for premature ejaculation is also available, although it is still in an early stage. Disorders of sexual desire have attracted much attention when women are affected but far less so when men are concerned. Whereas animal models appropriate for testing treatments for problems with erection and premature ejaculation are available, it is questionable whether such models of the desire disorders have predictive validity. There seems to be many factors involved both in reduced and enhanced sexual desire, most of which are unknown. In this review we present some data suggesting that an electroencephalographic analysis of brain activity during exposure to sexually relevant stimuli in male rats and men and during execution of sexual behaviors in male rats may provide useful information. The effects of a commonly used drug, ethanol, on the electroencephalogram recorded during sexual events in rats and men are also described. Although this approach to the analysis of the central nervous activity associated with sexual desire, arousal and behavior is still in its infancy, the data obtained so far show a remarkable similarity between men and rats. This suggests that animal studies of electroencephalographic responses to drugs in sexual contexts may be useful for predicting effects in the human male. PMID:24534418

  16. PREVALENCE OF SEXUAL DYSFUNCTION, INSOMNIA AND DETERIORATION OF THE QUALITY OF LIFE IN HYSTERECTOMYZED WOMEN (IN SPANISH

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    Saavedra-Orozco Héctor

    2014-04-01

    Full Text Available Introduction: the hysterectomy is a surgical procedure used for the treatment of uterine pathologies. It has been demonstrated that this procedure could affect negatively different fields and to impact the quality of life (QoL. Objective: to assess the sexual function, insomnia and the QoL in a group of hysterectomized women. Methods: cross-sectional study carried out with three validated scales: The short 6-item Female Sexual Function Index (FSFI-6, the Athens Insomnia Scale (AIS and the Menopause Rating Scale (MRS; in women with one or more years since the hysterectomy, aged between 40-59 years, belonging to afrodescendant and mestizo ethnic groups, who were from the department of Bolivar, Colombia. The participants were selected from their own communities. Results: 202 women were included in the study, with average age: 50±5.0 years. 10.8% were single, 85.1% were in free union and 3.8% were divorced or widowed. 69.8% were mestizo. The average score in the sexual grade between women with sexual partner was 11.3±4.0 (Range from 0 to 20, the higher the score, the better satisfaction. 29.7% had bilateral oophorectomy, 28.7% had unilateral oophorectomy and 41.5% kept the two ovaries. Just 20.3% used hormonal therapy. The sexual dysfunction was presented in the 71.7% of women, with disorder in orgasm in the 50.9%. 71.2% of women presented insomnia with an average score of 8.1±4.5. 28.6% expressed night awakenings. 42.5% of women manifested severe deterioration of the quality of life, 22.7%, 37.6% and 52.9% expressed deterioration of the somatic, psychological and urogenital domain, respectively. 90.4% of women had vasomotor symptoms and 25.7% reported to have severe or very severe sexual disorders. The presence of sexual dysfunction and insomnia had OR for severe deterioration of the quality of life of 2.1 and 2.4, respectively. Conclusions: the presence of sexual dysfunction and insomnia was high; both of them increased twice the risk of severe

  17. Ameliorating antipsychotic-induced weight gain by betahistine: Mechanisms and clinical implications.

    Science.gov (United States)

    Lian, Jiamei; Huang, Xu-Feng; Pai, Nagesh; Deng, Chao

    2016-04-01

    Second generation antipsychotic drugs (SGAs) cause substantial body weight gain/obesity and other metabolic side-effects such as dyslipidaemia. Their antagonistic affinity to the histaminergic H1 receptor (H1R) has been identified as one of the main contributors to weight gain/obesity side-effects. The effects and mechanisms of betahistine (a histaminergic H1R agonist and H3 receptor antagonist) have been investigated for ameliorating SGA-induced weight gain/obesity in both animal models and clinical trials. It has been demonstrated that co-treatment with betahistine is effective in reducing weight gain, associated with olanzapine in drug-naïve patients with schizophrenia, as well as in the animal models of both drug-naïve rats and rats with chronic, repeated exposure to olanzapine. Betahistine co-treatment can reduce food intake and increase the effect of thermogenesis in brown adipose tissue by modulating hypothalamic H1R-NPY-AMPKα (NPY: neuropeptide Y; AMPKα: AMP-activated protein kinase α) pathways, and ameliorate olanzapine-induced dyslipidaemia through modulation of AMPKα-SREBP-1-PPARα-dependent pathways (SREBP-1: Sterol regulatory element binding protein 1; PPARα: Peroxisome proliferator-activated receptor-α) in the liver. Although reduced locomotor activity was observed from antipsychotic treatment in rats, betahistine did not affect locomotor activity. Importantly, betahistine co-treatment did not influence the effects of antipsychotics on serotonergic receptors in the key brain regions for antipsychotic therapeutic efficacy. However, betahistine co-treatment reverses the upregulated dopamine D2 binding caused by chronic olanzapine administration, which may be beneficial in reducing D2 supersensitivity often observed in chronic antipsychotic treatment. Therefore, these results provide solid evidence supporting further clinical trials in treating antipsychotics-induced weight gain using betahistine in patients with schizophrenia and other mental

  18. Clinical correlates of enlarged prostate size in subjects with sexual dysfunction

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    Giovanni Corona

    2014-10-01

    Full Text Available Digito-rectal examination (DRE of the prostate provides useful information on the state of prostate growth and on the presence of suspected peripheral nodules. The aim of this study is to describe the clinical and biochemical correlates of finding an enlarged prostate size at DRE in subjects with sexual dysfunction (SD. A consecutive series of 2379 patients was retrospectively studied. The analysis was focused on a subset of subjects (n = 1823; mean age 54.7 ± 11.4 selected for being free from overt prostatic diseases. Several parameters were investigated. After adjusting for confounders, the presence of an enlarged prostate size at DRE was associated with a higher risk of metabolic syndrome (HR = 1.346 (1.129-1.759; P = 0.030, type 2 diabetes mellitus (HR = 1.489 (1.120-1.980; P = 0.006, increased LDL cholesterol (>100 mg dl−1 ; HR = 1.354 (1.018-1.801; P = 0.037 and increased mean blood pressure (BP values (HR = 1.017 (1.007-1.027 for each mmHg increment; P = 0.001. Accordingly, enlarged prostate size was also associated with a higher risk of arteriogenic erectile dysfunction (ED, as well as with other andrological conditions, such as varicocele and premature ejaculation (PE. PSA levels were significantly higher in subjects with enlarged prostate size when compared to the rest of the sample (HR = 3.318 (2.304; 4.799 for each log unit increment in PSA levels; P < 0.0001. Arteriogenic ED, according to different criteria, was also associated with increased PSA levels. In conclusion, our data support the need to examine prostate size either by clinical (DRE or biochemical (PSA inspection in subjects with SD, in order to have insights into the nature of the SD and the metabolic and cardiovascular (CV background of the patient.

  19. Improving BPH symptoms and sexual dysfunctions with a saw palmetto preparation? Results from a pilot trial.

    Science.gov (United States)

    Suter, Andreas; Saller, Reinhard; Riedi, Eugen; Heinrich, Michael

    2013-02-01

    In elderly men, benign prostatic hyperplasia (BPH) is a major risk factor for sexual dysfunctions (SDys). Additionally, the standard treatments for BPH symptoms, alpha blockers and 5-alpha-reductase inhibitors, cause SDys themselves. Preparations from saw palmetto berries are an efficacious and well-tolerated symptomatic treatment for mild to moderate BPH and have traditionally been used to treat SDys. We conducted an open multicentric clinical pilot trial to investigate whether the saw palmetto berry preparation Prostasan® influenced BPH symptoms and SDys. Eighty-two patients participated in the 8-week trial, taking one capsule of 320 mg saw palmetto extract daily. At the end of the treatment, the International Prostate Symptom Score was reduced from 14.4 ± 4.7 to 6.9 ± 5.2 (p BPH QoL-9 sex total improved from 137.3 ± 47.9 to 195.0 ± 56.3 (p BPH symptoms and reduced SDys. This was the first trial with saw palmetto to show improvement in BPH symptoms and SDys as well. [Corrections made here after initial online publication.] PMID:22522969

  20. No difference in sexual dysfunction after transabdominal preperitoneal (TAPP) approach for inguinal hernia with fibrin sealant or tacks for mesh fixation

    DEFF Research Database (Denmark)

    Pommergaard, Hans Christian; Burcharth, J; Andresen, K;

    2016-01-01

    study was to compare fibrin sealant versus tacks for fixation of mesh regarding sexual dysfunction in males and females. METHODS: Using the Danish Hernia Database, patients operated laparoscopically for groin hernia with a transabdominal preperitoneal (TAPP) procedure with fibrin sealant or tacks for...... mesh fixation were sent a questionnaire regarding sexual dysfunction. Sexually active patients without recurrence were evaluated in this study. RESULTS: Pain during sexual activity was present in 115 of 1019 (11.3 %) males and 17 of 147 (11.6 %) females. There was no difference between fibrin sealant...... and tacks for mesh fixation and no difference between genders. Pain intensity, characteristics and origin were comparable between fibrin sealant and tacks for both genders. We found a relationship between a higher rate of sexual dysfunction and lower age for both genders. CONCLUSION: We found no...

  1. MEIS1, a Promising Candidate Gene, Is Not Associated with the Core Symptoms of Antipsychotic-Induced Restless Legs Syndrome in Korean Schizophrenia Patients

    Science.gov (United States)

    Kang, Seung-Gul; Lee, Seung-Hwan; Kim, Leen

    2015-01-01

    Objective Restless legs syndrome (RLS) is a distressing sleep disorder to which individuals appear to be genetically predisposed. In the present study, we assumed that antipsychotic-induced RLS symptoms were attributable to differences in individual genetic susceptibility, and investigated whether MEIS1, a promising candidate gene, was associated with antipsychotic-induced RLS symptoms in schizophrenia patients. Methods All subjects were diagnosed with schizophrenia by board-certified psychiatrists using the Korean version of the Structured Clinical Interview for DSM-IV. We assessed antipsychotic-induced RLS symptoms in 190 Korean schizophrenic patients using the diagnostic criteria of the International Restless Legs Syndrome Study Group. Genotyping was performed for the rs2300478 and rs6710341 polymorphisms of the MEIS1 gene. Results We divided subjects into RLS symptom (n=96) and non-symptom (n=94) groups. There was no significant between-group difference in the genotype or allele frequencies of the two polymorphisms investigated, nor in the frequency of the rs2300478-rs6710341 haplotype. Conclusion Our data do not suggest that the rs2300478 and rs6710341 polymorphisms of the MEIS1 gene are associated with the core symptoms of antipsychotic-induced RLS in schizophrenia; different genetic mechanisms may underlie antipsychotic-induced vs. primary RLS. PMID:25866529

  2. Antidiabetic effect of α-mangostin and its protective role in sexual dysfunction of streptozotocin induced diabetic male rats.

    Science.gov (United States)

    Nelli, Giri Babu; K, Anand Solomon; Kilari, Eswar Kumar

    2013-12-01

    Sexual dysfunction is one of the diabetic complications in males. The present study aimed to evaluate the antidiabetic effect of α-mangostin and its protective role in sexual dysfunction of streptozotocin (STZ) induced diabetic male rats. Male Wistar rats were divided as control, diabetic control, diabetic rats administered with 25, 50 mg/kg body weight (bw) of α-mangostin and 1 mg/kg bw of gliclazide. The α-mangostin was administered once daily for a period of 55 days. On day 55 animals were sacrificed, serum was analyzed for testosterone levels, and sperm was collected from the epididymis and sperm parameters analyzed. Testis and epididymis were examined for antioxidant enzymes like superoxide dismutase (SOD), catalase, glutathione peroxidase (GPx) levels, lipidperoxidation products, and histopathological alterations. In diabetic rats, sperm count, motile sperms, viable sperms, and hypo-osmotic swelling tail coiled sperms were significantly decreased while sperm malformations increased when compared with normal rats. Serum testosterone levels and testicular 3β and 17 β-hydroxysteroid dehydrogenase levels were significantly decreased in diabetic rats. Significant reduction in testicular and epididymal SOD, catalase, GPx levels, and elevation in lipid peroxidation products were observed. However, α-mangostin treatment showed noteworthy recovery in all parameters towards the control levels. It may therefore be suggested that α-mangostin showed a protective effect against sexual dysfunction in STZ induced diabetic rats. PMID:23886300

  3. Linguistic Changes in Expressive Writing Predict Psychological Outcomes in Women With History of Childhood Sexual Abuse and Adult Sexual Dysfunction

    OpenAIRE

    Pulverman, Carey S.; Lorenz, Tierney A.; Meston, Cindy M.

    2014-01-01

    An expressive writing treatment was recently reported to reduce depressive symptoms and improve sexual function and satisfaction in a sample of female survivors of childhood sexual abuse (Meston, Lorenz, & Stephenson, 2013). We conducted a linguistic analysis of this data to determine whether pre-to posttreatment changes in participants’ language use were associated with the improvements in sexuality and depression. Linguistic Inquiry and Word Count (LIWC), a program that counts the use of wo...

  4. Internet-based cognitive behavioral therapy for sexual dysfunctions in women treated for breast cancer: design of a multicenter, randomized controlled trial

    NARCIS (Netherlands)

    S.B. Hummel; J.J.D.M. van Lankveld; H.S.A. Oldenburg; D.E.E. Hahn; E. Broomans; N.K. Aaronson

    2015-01-01

    Background: Sexual dysfunction is a prevalent, long-term complication of breast cancer and its treatment and can be treated effectively with face-to-face sexual counselling. However, relatively few women actually opt for face-to-face sex therapy, with many women indicating that it is too confronting

  5. Psychosocial Impairment as a Possible Cause of Sexual Dysfunction among Young Men with Mild Androgenetic Alopecia: A Cross-sectional Crowdsourcing Web-based Study

    OpenAIRE

    Alejandro Molina-Leyva; Isabel Caparros-delMoral; Pilar Gomez-Avivar; Mercedes Alcalde-Alonso; Jose Juan Jimenez-Moleon

    2016-01-01

    Finasteride 1 mg, one of the main treatments for male androgenetic alopecia (MAGA), may produce sexual dysfunction, but young men with MAGA could experience high psychosocial impairment because of changes in body image. Dissatisfaction with body image has been linked to an increase in problems with sexual function. To date no study has considered the possible effect of psychological impairment on sexual function of men with MAGA. Aim of our study was to explore the effect of psychosocial impa...

  6. Sexual Excitability and Dysfunctional Coping Determine Cybersex Addiction in Homosexual Males.

    Science.gov (United States)

    Laier, Christian; Pekal, Jaro; Brand, Matthias

    2015-10-01

    Cybersex addiction (CA) has been mostly investigated in heterosexual males. Recent findings have demonstrated an association between CA severity and indicators of sexual excitability, and that coping by sexual behaviors mediated the relationship between sexual excitability and CA symptoms. The aim of this study was to test this mediation in a sample of homosexual males. Seventy-one homosexual males were surveyed online. Questionnaires assessed symptoms of CA, sensitivity to sexual excitation, pornography use motivation, problematic sexual behavior, psychological symptoms, and sexual behaviors in real life and online. Moreover, participants viewed pornographic videos and indicated their sexual arousal before and after the video presentation. Results showed strong correlations between CA symptoms and indicators of sexual arousal and sexual excitability, coping by sexual behaviors, and psychological symptoms. CA was not associated with offline sexual behaviors and weekly cybersex use time. Coping by sexual behaviors partially mediated the relationship between sexual excitability and CA. The results are comparable with those reported for heterosexual males and females in previous studies and are discussed against the background of theoretical assumptions of CA, which highlight the role of positive and negative reinforcement due to cybersex use. PMID:26374928

  7. Cholinergic, noradrenergic and GABAergic control of sexual behaviour

    DEFF Research Database (Denmark)

    Nedergaard, Per

    acethylcholine, noradrenalin, GABA, sexual dysfunction, erectile dysfunction, rat, human, male, female......acethylcholine, noradrenalin, GABA, sexual dysfunction, erectile dysfunction, rat, human, male, female...

  8. Linguistic changes in expressive writing predict psychological outcomes in women with history of childhood sexual abuse and adult sexual dysfunction.

    Science.gov (United States)

    Pulverman, Carey S; Lorenz, Tierney A; Meston, Cindy M

    2015-01-01

    An expressive writing treatment was recently reported to reduce depressive symptoms and improve sexual function and satisfaction in a sample of female survivors of childhood sexual abuse (Meston, Lorenz, & Stephenson, 2013). We conducted a linguistic analysis of this data to determine whether pre- to posttreatment changes in participants' language use were associated with the improvements in sexuality and depression. Linguistic Inquiry and Word Count (LIWC), a program that counts the use of word categories within a text, was used to evaluate the impact of several word categories, previously associated with changes in mental health (Frattaroli, 2006), and shown to differ between childhood sexual abuse survivors and nonabused women (Lorenz & Meston, 2012), on treatment outcomes. A reduction in the use of the word "I" and an increase in positive emotion words were associated with decreased depression symptoms. A reduction in the use of "I" and negative emotion words were associated with improvement in sexual function and sexual satisfaction. The findings suggest that, because language may serve as an implicit measure of depression and sexual health, monitoring language changes during treatment may provide a reliable indicator of treatment response free of the biases of traditional self-report assessments. PMID:25793593

  9. Evaluation of the Family Physician Assistants’ Views to Sexual Dysfunction in a Training and Research Hospital

    OpenAIRE

    Yusuf A. Güçlü1; Yasemin K. Öztürk1; Özgür E. Öztürk; et al.

    2016-01-01

    Aim: The aim of the study is to investigate the view of sight of the family medicine residents about the sexual education and sexual functional disorders. Methods: A sectional descriptive questionnaire form study is designed at Tepecik Training Research Hospital during May and June 2013. The questionnaire about sexual education and sexual functional disorders is applied to all the family medicine residents who agreed to participate the study. Data are decoded in Microsoft Excel program; de...

  10. Clinico-demographic profile, sexual dysfunction and readiness to change in male alcohol dependence syndrome inpatients in a tertiary hospital.

    Science.gov (United States)

    Pandey, A K; Sapkota, N; Tambi, A; Shyangwa, P M

    2012-03-01

    Persons with prolonged and heavy alcohol use generally suffer from alcohol dependence syndrome (ADS) and develop physical, sexual as well as psychiatric co-morbidity. Successful recovery to normalcy depends on multiple factors including patient's motivation. To study clinico-demographic profile, reasons for initiating alcohol use, sexual and psychiatric disorders and eagerness for treatment and quitting alcohol in ADS inpatients. Fifty consecutive ADS inpatients with matching controls were enrolled. Clinico-demographic profile, factors for initiating alcohol use, psychiatric and sexual co-morbidity and want for treatment and being abstinent was studied applying relevant scales. All subjects were males with a mean age of 37.5 years, 80% were married, majority were Hindu (88%) and from nuclear families (56%). Fifty two percent had an education level of Graduation or more and 68% of patients reported peer pressure to be the initiating factor for alcohol use. Seventy six percent had psychiatric co-morbidity including personality Problems and other Psychiatric disorders 19(38%), delirium tremens 14 (28.00%) and Mood disorders 12(24%).Depression being most common mood disorder (14%). Nicotine was the most common other substance of use 32 (64%). Sixty eight percent of the patient reported one or another sexual dysfunction. 68% of ADS inpatients acknowledged of having problems related to their drinking, expressed desire for change and were eager to avail treatment and to remain abstinent. ADS patients commonly suffer from psychiatric co-morbidity and sexual dysfunctions. They also wish to have effective treatment and to quit alcohol. PMID:23441492

  11. Prevalence and risk factors for female sexual dysfunction in women attending a medical clinic in south India

    Directory of Open Access Journals (Sweden)

    Singh J

    2009-01-01

    Full Text Available Background: Reports from India on the prevalence and determinants of female sexual dysfunction (FSD are scant. Aims: To determine the prevalence and risk factors for FSD. Settings and Design: A cross-sectional survey in a medical outpatient clinic of a tertiary care hospital. Materials and Methods: We administered a Tamil version of the Female Sexual Function Index (FSFI to 149 married women. We evaluated putative risk factors for FSD. We elicited participant′s attributions for their sexual difficulties. Statistical Analysis: We estimated the prevalence of possible FSD and sexual difficulties from published FSFI total and domain cut-off scores. We used logistic regression to identify risk factors for possible FSD. Results: FSFI total scores suggested FSD in two-thirds of the 149 women (73.2%; 95% confidence intervals [CI] 65.5% to 79.6%. FSFI domain scores suggested difficulties with desire in 77.2%; arousal in 91.3%; lubrication in 96.6%; orgasm in 86.6%, satisfaction in 81.2%, and pain in 64.4%. Age above 40 years (odds ratios [OR] 11.7; 95% CI 3.4 to 40.1 and fewer years of education (OR 1.2; 95% CI 1.0 to 1.3 were identified by logistic regression as contributory. Women attributed FSD to physical illness in participant or partner, relationship problems, and cultural taboos but none had sought professional help. Conclusions: Sexual problems suggestive of dysfunction, as suggested by FSFI total and domain scores, are highly prevalent in the clinic setting, particularly among women above 40 and those less educated, but confirmation using locally validated cut-off scores of the FSFI is needed.

  12. Sexual dysfunction in climacteric women of African descent from the Colombian Caribbean region = Disfunción sexual en mujeres climatéricas afrodescendientes del Caribe Colombiano

    Directory of Open Access Journals (Sweden)

    Monterrosa Castro, Alvaro De Jesus

    2014-01-01

    Full Text Available Introduction: After the United States and Brazil, Colombia is the third American country with the greatest population of African descent. Objective: To estimate the prevalence of sexual dysfunction (SD in climacteric women of African descent. Methods: Cross sectional study carried out with the Female Sexual Function Index (FSFI, in healthy women, whose mother and father were of black race, living in municipalities from the Colombian Caribbean region, who volunteered to anonymously participate in the study, and were recruited in their communities. Higher scores correlated with better sexuality. Results: 461 women were studied; 305 (66.2% with sexual activity; 70.8% were premenopausal and 29.2%, postmenopausal. Average scores of the domains were: Sexual desire (4.1 ± 1.1, sexual arousal (4.4 ± 1.0, lubrication (4.9 ± 1.0, orgasm (4.7 ± 1.0, satisfaction (5.3 ± 1.0 and pain (4.3 ± 1.5. Average total score was 27.7 ± 4.7. Prevalence of SD was 38.4%. Smoking (OR: 3.3 [IC95%: 1.0-10.6; p = 0.041] and arterial hypertension (OR: 2.2 [IC95%:1.1-4.4; p = 0.026] increased the risk of SD, while schooling higher than ten years (OR: 0.4 [IC95%: 0.2-0.8; p = 0.003] decreased it. Prevalence of SD increased with the change in the menopausal status (p <0,001. All domains deteriorated, except pain, with the transition to the postmenopausal status (p <0.001. Conclusion: In females of African descent from the Colombian Caribbean region, one third of the premenopausal and half of the postmenopausal have SD.

  13. Healthy Sexuality

    Medline Plus

    Full Text Available ... disease, dysfunction, or infirmity. Sexual health requires a positive and respectful approach to sexuality and sexual relationships, ... pleasure and satisfaction. Sex also has many other positive health benefits, such as reducing stress, improving self- ...

  14. Healthy Sexuality

    Medline Plus

    Full Text Available ... sexual health as “…a state of physical, emotional, mental and social well-being in relation to sexuality; it is not merely the absence of disease, dysfunction, or infirmity. Sexual health requires a positive ...

  15. Antipsychotic-induced catalepsy is attenuated in mice lacking the M4 muscarinic acetylcholine receptor

    DEFF Research Database (Denmark)

    Fink-Jensen, Anders; Schmidt, Lene S; Dencker, Ditte;

    2011-01-01

    A delicate balance exists between the central dopaminergic and cholinergic neurotransmitter systems with respect to motor function. An imbalance can result in motor dysfunction as observed in Parkinson's disease patients and in patients treated with antipsychotic compounds. Cholinergic receptor a...

  16. PA03.23. To Evaluate the efficacy of “Vajikar Kalp” in Male sexual dysfunction

    OpenAIRE

    Khedkar, Amol; ,

    2013-01-01

    Purpose: To evaluate the efficacy of an aphrodisiac preparation in male sexual dysfunction. Method: The Vajikar Kalp was administered in 30 patients at the dosage of 2 gms twice a day with luke warm cow's milk. The combination was made of 1.Asparagus Racemosa - 500 mg, 2.Tribulus Terrestris - 500 mg, 3. Mucuna Pruriens - 500 mg, 4. Withania Somnifera - 500 mg. Patients were observed on days 0, 15, 30, 60 and 90. International Index of Erectile Function was used to assess the improvement. Othe...

  17. SSRI-induced sexual dysfunction: fluoxetine, paroxetine, sertraline, and fluvoxamine in a prospective, multicenter, and descriptive clinical study of 344 patients.

    Science.gov (United States)

    Montejo-González, A L; Llorca, G; Izquierdo, J A; Ledesma, A; Bousoño, M; Calcedo, A; Carrasco, J L; Ciudad, J; Daniel, E; De la Gandara, J; Derecho, J; Franco, M; Gomez, M J; Macias, J A; Martin, T; Perez, V; Sanchez, J M; Sanchez, S; Vicens, E

    1997-01-01

    The authors analyzed the incidence of sexual dysfunction (SD) with different selective serotonin reuptake inhibitors (SSRIs; fluoxetine, fluvoxamine, paroxetine, and sertraline) and hence the qualitative and quantitative changes in SD throughout time in a prospective and multicenter study. Outpatients (192 women and 152 men; age = 39.6 +/- 11.4 years) under treatment with SSRIs were interviewed with an SD questionnaire designed for this purpose by the authors and that included questions about the following: decreased libido, delayed orgasm or anorgasmia, delayed ejaculation, inability to ejaculate, impotence, and general sexual satisfaction. Patients with the following criteria were included: normal sexual function before SSRI intake, exclusive treatment with SSRIs or treatment associated with benzodiazepines, previous heterosexual or self-erotic current sexual practices. Excluded were patients with previous sexual dysfunction, association of SSRIs with neuroleptics, recent hormone intake, and significant medical illnesses. There was a significant increase in the incidence of SD when physicians asked the patients direct questions (58%) versus when SD was spontaneously reported (14%). There were some significant differences among different SSRIs: paroxetine provoked more delay of orgasm or ejaculation and more impotence than fluvoxamine, fluoxetine and sertraline (chi 2, p < .05). Only 24.5% of the patients had a good tolerance of their sexual dysfunction. Twelve male patients who suffered from premature ejaculation before the treatment preferred to maintain delayed ejaculation, and their sexual satisfaction, and that of their partners, clearly improved. Sexual dysfunction was positively correlated with dose. Patients experienced substantial improvement in sexual function when the dose was diminished or the drug was withdrawn. Men showed more incidence of sexual dysfunction than women, but women's sexual dysfunction was more intense than men's. In only 5.8% of

  18. Evaluation of the Family Physician Assistants’ Views to Sexual Dysfunction in a Training and Research Hospital

    Directory of Open Access Journals (Sweden)

    Yusuf A. Güçlü1

    2016-03-01

    Full Text Available Aim: The aim of the study is to investigate the view of sight of the family medicine residents about the sexual education and sexual functional disorders. Methods: A sectional descriptive questionnaire form study is designed at Tepecik Training Research Hospital during May and June 2013. The questionnaire about sexual education and sexual functional disorders is applied to all the family medicine residents who agreed to participate the study. Data are decoded in Microsoft Excel program; descriptive statistics are made. Results: 56 Family Medicine residents with an average age of 29,7±4,0 years were participated in the study. 27 (48.2% of the residents were male while 29 (51.8% were female. The overall rates of the beliefs about the primary care physicians must be interested in sexual problems were 87,5% (n=49; primary care physicians are responsible for sexual educations 75% (n=42. Though 53,6% of them told that they aren’t comfortable at talking sexual problems with the patients. Majority of the residents (78,6%; n=44 thought that they have a lack of knowledge about sexual functional disorders. Only one (1,8% of them was using sexual function scales while examining a patient. Conclusion: Majority of the Family Medicine residents know the role of primary health care physicians’ role at sexual disorders. They were aware about the importance of sexual education in primary care. Though there is a lack of knowledge and need about sexual disorders during the residency programs of family medicine.

  19. Sexual dysfunction is more than twice as frequent in Danish female predialysis patients compared to age- and gender-matched healthy controls

    DEFF Research Database (Denmark)

    Prescott, Lotte; Eidemak, Inge; Harrison, Adrian Paul;

    2014-01-01

    .2 ± 2.1 vs. 20.1 ± 1.7, respectively, p = 0.048), more frequent sexual distress (44 vs. 22 %, respectively, p = 0.044), and more frequent sexual dysfunction (41 vs. 17 %, respectively, p = 0.041). There was no difference between the patients' and the controls' depression scores (12.2 ± 2.2 vs. 8.6 ± 1.......1, respectively, p = 0.180). CONCLUSION: Sexual dysfunction was found to be more than two times as frequent in Danish female predialysis patients with CKD stage 4-5 compared to age- and gender-matched healthy controls, and this result emphasizes the need for attention towards sexual function in the treatment...

  20. Female sexual dysfunction in young adult women - Impact of age and lifestyle

    Science.gov (United States)

    Stoian, Dana; PAter, Liana; Pater, Flavius; Craciunescu, Mihaela

    2014-12-01

    Female sexual function is a difficult entity to be assessed. Subjective factors and interview biases can change the perception of it. Using validated questionnaires can improve the scientific approach to this matter. There is a huge difference of severity and incidence among young, apparent healthy women, which are in a harmonious relationship. We evaluated 320 healthy women, with stable sexual active relationship, with no know depressive disease, endocrinological and metabolic pathology, no premature menopause, no malignancy. We compose a mathematic model to study the impact of age, and body weight on the sexual function, with FSFI total score as surrogate marker. We observed that even in healthy women, increase in age and/or weight/body mass significantly impair general sexual function.

  1. NETWORK POSITION AND SEXUAL DYSFUNCTION: IMPLICATIONS OF PARTNER BETWEENNESS FOR MEN*

    OpenAIRE

    Cornwell, Benjamin; Laumann, Edward O.

    2011-01-01

    This paper combines relational perspectives on gender identity with social network structural perspectives on health to understand men’s sexual functioning. We argue that network positions that afford independence and control over social resources are consistent with traditional masculine roles and may therefore affect men’s sexual performance. For example, when a heterosexual man’s female partner has more frequent contact with his confidants than he does–a situation that we refer to as partn...

  2. Antipsychotic-induced catalepsy is attenuated in mice lacking the M4 muscarinic acetylcholine receptor

    OpenAIRE

    Fink-Jensen, Anders; Schmidt, Lene S.; Dencker, Ditte; Schülein, Christina; Wess, Jürgen; Wörtwein, Gitta; Woldbye, David P.D.

    2011-01-01

    A delicate balance exists between the central dopaminergic and cholinergic neurotransmitter systems with respect to motor function. An imbalance can result in motor dysfunction as observed in Parkinson’s disease patients and in patients treated with antipsychotic compounds. Cholinergic receptor antagonists can alleviate extrapyramidal symptoms in Parkinson’s disease and motor side effects induced by antipsychotics. The effects of anticholinergics are mediated by muscarinic receptors of which ...

  3. Sexual dysfunction in men in the first 9 months after myocardial infarction [Dysfunkcje seksualne u mężczyzn w ciągu pierwszych 9 miesięcy po przebytym zawale serca

    OpenAIRE

    Puchalski, Bartosz; Szymański, Filip; Kowalik, Robert; Filipiak, Krzysztof Jerzy

    2013-01-01

    Objectives. The aim of the study is to assess the frequency of sexual dysfunction in men after myocardial infarction (MI).Methods. 62 men were asked to fill IIEF 15 to assess sexual dysfunction 3 and 9 months after MI.Results. Erectile dysfunction (ED), orgasmic dysfunction, decreased sexual desire, decreased intercourse satisfaction, decreased overall satisfaction were recognized respectively by: 61.3%, 24.2%, 62.9%, 71%, 54.8% of men 3 months after MI, and 51.6%, 17.7%, 58.1%, 77.4%, 59.7% ...

  4. Depression is correlated with the psychological and physical aspects of sexual dysfunction in men.

    Science.gov (United States)

    Pastuszak, A W; Badhiwala, N; Lipshultz, L I; Khera, M

    2013-09-01

    Few studies have objectively examined the relationship between depression and various stages of sexual function. Here we associate depression and sexual function using validated questionnaires. A retrospective review of 186 men was performed; demographics and serum hormone levels were obtained. Responses to questionnaires evaluating depressive symptoms (Patient Health Questionnaire (PHQ-9)), sexual function (International Index of Erectile Function (IIEF)) and hypogonadal symptoms (quantitative Androgen Decline in the Aging Male (qADAM)) completed by each patient were correlated using Spearman's rank correlation. Mean±s.d. subject age: 52.6±12.7 years; mean serum hormone levels: TT 429.8±239.2 ng dl(-1), free testosterone 9.72±7.5 pg ml(-1) and estradiol 34.4±22.8 pg ml(-1). Negative correlations were observed between total PHQ-9 score and the sexual desire (ρ=-0.210, P=0.006), intercourse satisfaction (ρ=-0.293, Ppsychological as well as physical aspects of sexual function. PMID:23466661

  5. Possible benefits of robot-assisted rectal cancer surgery regarding urological and sexual dysfunction

    DEFF Research Database (Denmark)

    Broholm Andersen, Malene; Pommergaard, H-C; Gögenür, I

    2015-01-01

    AIM: Robot-assisted surgery for rectal cancer may result in lower rates of urogenital dysfunction compared with laparoscopic surgery. A systematic review was conducted of studies reporting urogenital dysfunction after robot-assisted rectal cancer surgery. METHOD: PubMed, Embase and the Cochrane...... months' follow-up [MD -2.59 (-4.25, -0.94),] P = 0.002] and 6 months' follow-up [MD -3.06 (-4.53, -1.59), P = 0.0001] were better after robot-assisted than laparoscopic surgery. CONCLUSION: Although there were few data and no randomized controlled trials the results of the review suggested that robot...

  6. Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo - controlled study

    OpenAIRE

    Akhtari, Elham; Raisi, Firoozeh; Keshavarz, Mansoor; Hosseini, Hamed; Sohrabvand, Farnaz; Bioos, Soodabeh; Kamalinejad, Mohammad; Ghobadi, Ali

    2014-01-01

    Background Tribulus terrestris as a herbal remedy has shown beneficial aphrodisiac effects in a number of animal and human experiments. This study was designed as a randomized double-blind placebo-controlled trial to assess the safety and efficacy of Tribulus terrestris in women with hypoactive sexual desire disorder during their fertile years. Sixty seven women with hypoactive sexual desire disorder were randomly assigned to Tribulus terrestris extract (7.5 mg/day) or placebo for 4 weeks. De...

  7. Prevalence of sexual dysfunction and its associated factors in women aged 40-65 years with 11 years or more of formal education: a population-based household survey

    Directory of Open Access Journals (Sweden)

    Ana L. R. Valadares

    2008-01-01

    Full Text Available OBJECTIVE: To evaluate the prevalence of sexual dysfunction and its associated factors in middle-aged women with 11 years or more of formal education. METHODS: A cross-sectional, population-based study was carried out using an anonymous, self-response questionnaire. A total of 315 Brazilian-born women, 40-65 years of age with 11 years or more of schooling, participated in the study. The instrument used in the evaluation was based on the Short Personal Experiences Questionnaire. Sexual dysfunction was calculated from the mean score of sexual responsiveness (pleasure in sexual activities, excitation and orgasm, frequency of sexual activities and libido. Sociodemographic and clinical factors were evaluated. Poisson multiple regression analysis was carried out and the prevalence ratios with respective 95% confidence intervals (95%CI were calculated. RESULTS: The prevalence of sexual dysfunction was 35.9% among our study population. Multiple regression analysis showed that sexual dysfunction was positively associated with older age (prevalence ratios=1.04; 95%CI:1.01-1.07 and with the presence of hot flashes (prevalence ratios=1.37; 95%CI:1.04-1.80. Having a sexual partner (PR=0.47; 95%CI:0.34-0.65 and feeling well or excellent (prevalence ratios= 0.68; 95%CI: 0.52-0.88 were factors associated with lower sexual dysfunction scores. CONCLUSIONS: Sexual dysfunction was present in more than one-third of women that were 40-65 years of age with 11 years or more of formal education. Within that age group, older age and hot flashes were associated with higher sexual dysfunction scores, whereas feeling well and having a sexual partner were associated with better sexuality.

  8. The dark side of 5α-reductase inhibitors' therapy: sexual dysfunction, high Gleason grade prostate cancer and depression.

    Science.gov (United States)

    Traish, Abdulmaged M; Mulgaonkar, Ashwini; Giordano, Nicholas

    2014-06-01

    With aging, abnormal benign growth of the prostate results in benign prostate hyperplasia (BPH) with concomitant lower urinary tract symptoms (LUTS). Because the prostate is an androgen target tissue, and transforms testosterone into 5α-dihydrotestosterone (5α-DHT), a potent androgen, via 5α-reductase (5α-R) activity, inhibiting this key metabolic reaction was identified as a target for drug development to treat symptoms of BPH. Two drugs, namely finasteride and dutasteride were developed as specific 5α-reductase inhibitors (5α-RIs) and were approved by the U.S. Food and Drug Administration for the treatment of BPH symptoms. These agents have proven useful in the reducing urinary retention and minimizing surgical intervention in patients with BPH symptoms and considerable literature exists describing the benefits of these agents. In this review we highlight the adverse side effects of 5α-RIs on sexual function, high grade prostate cancer incidence, central nervous system function and on depression. 5α-Rs isoforms (types 1-3) are widely distributed in many tissues including the central nervous system and inhibition of these enzymes results in blockade of synthesis of several key hormones and neuro-active steroids leading to a host of adverse effects, including loss of or reduced libido, erectile dysfunction, orgasmic dysfunction, increased high Gleason grade prostate cancer, observed heart failure and cardiovascular events in clinical trials, and depression. Considerable evidence exists from preclinical and clinical studies, which point to significant and serious adverse effects of 5α-RIs, finasteride and dutasteride, on sexual health, vascular health, psychological health and the overall quality of life. Physicians need to be aware of such potential adverse effects and communicate such information to their patients prior to commencing 5α-RIs therapy. PMID:24955220

  9. Comparing the Efficacy of Bupropion and Amantadine on Sexual Dysfunction Induced by a Selective Serotonin Reuptake Inhibitor

    Directory of Open Access Journals (Sweden)

    Zahiroddin

    2015-12-01

    Full Text Available Background Antidepressant-induced sexual dysfunction (SD is a common problem, associated with a significant risk of non-adherence. Selective Serotonin Reuptake Inhibitors (SSRIs are associated with a substantial risk of SD. Only 10 % of patients show spontaneous improvement during follow up period. Objectives This study aimed to compare two proposed medication (bupropion vs. amantadine in alleviating SD in patients treated with SSRIs. Patients and Methods In a randomized, single-blinded, clinical trial in Iran, 46 patients were recruited based on DSM-IV-TR criteria and semi-structured interview. Then, they were randomized into two treatment groups using table of random numbers. Eight patients were excluded and finally 38 patients completed the study which lasted for 4 weeks. Twenty patients were given bupropion, 18 patients were randomly assigned to another group, and given amantadine. Patients were assessed with the Arizona sexual experience scale (ASEX at baseline and 4 weeks after the treatment. Results A total of 38 patients completed the study (18 patients in amantadine vs. 20 patients in bupropion.The mean ASEX scores gradually declined in both study groups during the trial. The reduction of ASEX score in bupropion group was more than that of amantadine group that was statistically significant. So, the addition of bupropion at higher doses appears to be more effective approach in comparison with amantadine. Conclusions These results provide empirical support for conducting a further study on comparing different add-on strategies for treating drug-induced SD.

  10. Prevalence and predictors of concomitant low sexual desire/interest and new-onset erectile dysfunction - a picture from the everyday clinical practice.

    Science.gov (United States)

    Salonia, A; Clementi, M C; Ventimiglia, E; Colicchia, M; Capogrosso, P; Castiglione, F; Castagna, G; Boeri, L; Suardi, N; Cantiello, F; Damiano, R; Montorsi, F

    2014-09-01

    Prevalence and risk factors of concomitant primary low sexual desire/interest (LSD/I) and subsequent new-onset erectile dysfunction (ED) in men have been only partially investigated. We looked at the sociodemographic and clinical predictors of the concomitant condition of primary LSD/I - defined as the reduction in the usual level of SD/I which precedes ED or another sexual dysfunction - and new-onset ED (LSD/I + ED) in a cohort of consecutive Caucasian-European patients seeking their first medical help for sexual dysfunction at a single outpatient clinic in the everyday clinical practice setting. Data from 439 sexually active patients were analysed. Health-significant comorbidities were scored with the Charlson Comorbidity Index (CCI). Patients' LSD/I were evaluated according to the findings of a comprehensive sexual history. Moreover, patients completed the International Index of Erectile Function (IIEF). Descriptive statistics and logistic regression models tested the prevalence and predictors of LSD/I + ED as compared with ED only. Of the 439 men, LSD/I + ED was observed in 33 (4.2%) individuals. One of three men with LSD/I + ED was younger than 40 years. Patients complaining of LSD/I + ED or ED alone did not differ in terms of hormonal milieu. No significant differences emerged between groups in terms of sexual orientation, rates of stable sexual relationships, educational status, recreational habits and comorbid sexual dysfunctions. Patients with LSD/I + ED had significantly lower IIEF-sexual desire and IIEF-overall satisfaction scores than ED-only individuals (all p ≤ 0.003). At multivariable analysis younger age and severe CCI scores emerged as independent predictors of LSD/I + ED (all p ≤ 0.04). These findings showed that primary LSD/I is concomitant with new-onset ED in less than 5% of men seeking first medical help. Younger age and severe CCI emerged as independent predictors of LSD/I + ED. Patients with both conditions reported an impaired overall

  11. Aspectos diagnósticos e terapêuticos das disfunções sexuais femininas Diagnostic and therapeutic aspects of female sexual dysfunctions

    Directory of Open Access Journals (Sweden)

    Carmita Helena Najjar Abdo

    2006-01-01

    Full Text Available Este artigo apresenta o desenvolvimento do conceito de normal e patológico em sexualidade, com base nos estudos populacionais de Kinsey, bem como a evolução do conceito de ciclo de resposta sexual, desde Masters e Johnson até Basson. Trata das classificações das disfunções sexuais, as quais têm como base o ciclo de resposta sexual. Os aspectos diagnósticos das disfunções sexuais femininas ressaltam a primazia da observação clínica minuciosa, enfatizando que o diagnóstico deve considerar o tempo de evolução do quadro, as condições do(a parceiro(a e as características do estímulo sexual (quanto ao foco, à duração e à intensidade. Além disso, a distinção entre disfunção primária ou secundária, generalizada ou situacional, bem como idade e experiência sexual da mulher, são parâmetros diagnósticos. Os aspectos terapêuticos referem a importância de uma equipe multidisciplinar, capaz de oferecer à mulher acompanhamento psicoterápico e medicamentoso (com antidepressivos, ansiolíticos, hormônios, entre outros, além de suporte psicoeducacional. Ressalta-se a necessidade de se avaliar caso a caso para a instituição de terapêutica individualizada. Embora os quadros de disfunções sexuais da mulher já sejam bem conhecidos, os recursos disponíveis para esse tratamento ainda são restritos. Novas pesquisas deverão contribuir para mudar essa realidade e fazer frente aos progressos terapêuticos relativos às disfunções sexuais masculinas.This article discusses the development of the concepts of normal and pathological in sexuality from the perspective of the population studies by Kinsey, as well as the development of the concept of sexual response cycle, from Masters and Johnson to Basson. The article deals with the classification of sexual dysfunctions, based on the sexual response cycle. Aspects of the diagnosis of female sexual dysfunctions reveal the importance of a detailed clinical observation

  12. Sexually Dimorphic Serotonergic Dysfunction in a Mouse Model of Huntington's Disease and Depression

    OpenAIRE

    Thibault Renoir; Zajac, Michelle S; Xin Du; Pang, Terence Y.; Leah Leang; Caroline Chevarin; Laurence Lanfumey; Hannan, Anthony J

    2011-01-01

    Depression is the most common psychiatric disorder in Huntington's disease (HD) patients. In the general population, women are more prone to develop depression and such susceptibility might be related to serotonergic dysregulation. There is yet to be a study of sexual dimorphism in the development and presentation of depression in HD patients. We investigated whether 8-week-old male and female R6/1 transgenic HD mice display depressive-like endophenotypes associated with serotonergic impairme...

  13. Influence of cyproheptadine on clomipramine induced sexual dysfunction in male rats

    Directory of Open Access Journals (Sweden)

    D. Sheshadri Shekar

    2016-08-01

    Conclusions: The cyproheptadine a drug used as appetizer has the ability to elevate testosterone levels; it has also protected the testis from clomipramine induced damage. The sexual behaviour of the rats which were under treatment with clomipramine was also restored partially in TD and 2TD whereas the rats which were under and frac12; TD clmp treatment were restored to normal. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1359-1365

  14. Sexual Problems

    Medline Plus

    Full Text Available ... is similar to what happens when a person has a phobia or fear. Hypoactive sexual desire disorder, ... There are many clitoral devices, but only one has FDA-approval for treatment of female sexual dysfunction. ...

  15. The role of vegetative and vascular disturbances in development of sexual dysfunctions. Chapter 11

    International Nuclear Information System (INIS)

    It is well known that in clinics of late consequences of low radiation doses action the principle place takes vegetative and vascular dysfunctions. For estimation of vegetative-vascular system tone the Danini-Ashner of eye-heard reflex is studied. Status of the reflex for 120 examined patients was studied. Results of investigation of Danini-Ashner reflex in relation of received dose of radiation, as well as results of skin temperature of sicks with different levels of low radiation doses late consequences are presented. For study of vegetative-vascular system the electro-skin resistance method was used as well

  16. PA01.55. Efficacy of ‘Ashwa’ capsule in male sexual dysfunction

    OpenAIRE

    Padavi, D. M.; Rathod, Amarsing; ,

    2012-01-01

    Purpose: 1. Now a day's erectile dysfunction is very common Problem among The people and available measures or managament are not up to the mark & hence this disease still having ray of hope & Ayurveda could be the solution. 2. To put forth effect of Cap. Ashwa in such way to accept the medicine in the modern era. Method: Open Uncontrolled study with 30 Sample size of age group 24 70 years treated with Cap. Ashwa 1 gm BD with milk (Shatavari, Aswagandha, gokshur, Kronchbeej 250 mg each) Param...

  17. Clinical investigation of menopausal women with sexual dysfunction%绝经期女性性功能障碍的相关因素分析

    Institute of Scientific and Technical Information of China (English)

    林丽; 鲍云云; 蔡珠华

    2014-01-01

    目的:调查分析绝经期女性性功能障碍情况。方法:选取我院2011年3月至2012年3月收治的围绝经期女性共210例。通过调查问卷的形式调查患者的性功能障碍情况。结果:选出的210例绝经期患者功能障碍发生率为75.2%。不同年龄段的绝经女性其性功能障碍评分有显著性差异:50岁以上患者的评分均明显要低于50岁以下患者,50岁以上患者的女性性功能障碍评分为(20.2±1.2)分,而50岁以下的患者的得分则是(23.5±1.0)分。50岁以下的绝经女性其性功能障碍主要表现为性满意度低和性高潮障碍,两者的发生率分别为88.6%和72.7%;而50岁以上患者的主要性功能障碍主要表现在性欲和性唤起两方面,其发生率分别是69.3%和75.4%。结论:影响绝经女性出现性功能障碍的因素包括患者年龄、基础疾病以及雌激素的补充。50岁以下的绝经女性性功能障碍主要表现为性满意度低,以及性高潮障碍;50岁以上患者的性功能障碍主要表现在性欲和性唤起两方面。%Objectives:To investigate the sexual dysfunction of outpatient menopausal women.Methods:210 perimenopausal women admitted to our hospital from March 2011 to March 2012 were surveyed through ques-tionnaires to learn their sexual dysfunction condition.Results:75.2% of the 210 menopausal patients had sexual dysfunction problem.The sexual dysfunction score of menopausal women at different ages were significantly differ-ent:scores of patients over 50 (23.5 ±1.0)were significantly lower than patients below 50(20.2 ±1.2).For menopausal women below 50 years old,the sexual dysfunction mainly included low sexual satisfaction (88.6%) and orgasm (72.7%);while for patients over 50,they were difficulty in sexual desire (69.3%)and arousal (75. 4%).Conclusions:Factors of sexual dysfunction in postmenopausal females include age,underlying disease,and estrogen supplement

  18. Frequency of sexual dysfunction and other reproductive side-effects in patients with schizophrenia treated with risperidone, olanzapine, quetiapine, or haloperidol: the results of the EIRE study.

    Science.gov (United States)

    Bobes, J; Garc A-Portilla, M P; Rejas, J; Hern Ndez, G; Garcia-Garcia, M; Rico-Villademoros, F; Porras, A

    2003-01-01

    Atypical antipsychotics seem to differ mainly in their tolerability profile. The aim of this cross-sectional study, the Estudio de Investigaci n de Resultados en Esquizofrenia (Outcomes Research Study in Schizophrenia; EIRE study), was to assess in a clinical setting the frequency of several side-effects related to haloperidol, risperidone, olanzapine, and quetiapine. This article addresses sexual dysfunction and other reproductive side-effects (gynecomastia, menorrhage, amenorrhea, and galactorrhea). We recruited outpatients diagnosed with schizophrenia according to Diagnostic and Statistical Manual of Mental Disorders (DSM-IV; American Psychiatric Association, 1994) criteria and who had received a single antipsychotic (risperidone, olanzapine, quetiapine, or haloperidol) for at least 4 weeks. During a single visit, we collected data, including demographic and clinical characteristics, current antipsychotic and concomitant treatment, and adverse effects listed in a modified version of the UKU Scale. We used a Chi-squared test to determine pairs comparisons of the frequency of adverse reactions between treatments. To estimate risk of a given adverse reaction with a given treatment, we used a logistic regression method. We assessed 636 evaluable patients out of 669 recruited. Frequency of sexual dysfunction was high with haloperidol (38.1%) and also with olanzapine (35.3%), quetiapine (18.2%), and risperidone (43.2%). We found the frequency of other reproductive side-effects to be relatively low with all four drugs: haloperidol (6.9%), olanzapine (6.4%), quetiapine (2.7%), and risperidone (11.7%). Sexual dysfunction appeared to be dose-related with haloperidol, risperidone, and olanzapine. Risperidone and olanzapine showed a higher risk of sexual dysfunction and other reproductive sideeffects than haloperidol. Quetiapine showed a lower risk of sexual dysfunction during short-term treatment ( 12 weeks) are lacking. Our results suggest that none of the atypical

  19. Fluoroquinolone-macrolide combination therapy for chronic bacterial prostatitis: retrospective analysis of pathogen eradication rates, inflammatory findings and sexual dysfunction

    Institute of Scientific and Technical Information of China (English)

    Vittorio Magri; Emanuele Montanari; Vi(s)nja (S)kerk; Alemka Markoti(c); Emanuela Marras; Antonella Restelli; Kurt G Naber; Gianpaolo Perletti

    2011-01-01

    We previously demonstrated the safety and efficacy of fluoroquinolone-macrolide combination therapy in category Ⅱ chronic bacterial prostatitis (CBP).The aim of this study is to retrospectively compare the microbiological and clinical findings of two treatment schemes for CBP based on the combination of azithromycin (500 mg,thrice-weekly) with a once-daily 500-or 750-mg dose of ciprofloxacin (Cipro-500 or Cipro-750 cohort,respectively).Combined administration of azithromycin (1500 mg week-1) with ciprofloxacin at the rate of 750 mg day-1 for 4 weeks rather than at 500 mg day-1 for 6 weeks increased the eradication rates from 62.35% to 77.32% and the total bacteriological success from 71.76% to 85.57%.A significant decrease in pain and voiding signs/symptoms and a significant reduction in inflammatory leukocyte counts and serum prostate-specific antigen (PSA) were sustained throughout an 18-month follow-up period in both groups.Ejaculatory pain,haemospermia and premature ejaculation were significantly attenuated on microbiological eradication in both groups,but the latter subsided more promptly in the Cipro-750 cohort.In total,59 Cipro-750 patients showed mild-to-severn erectile dysfunction (ED) at baseline,while 22 patients had no ED on microbiological eradication and throughout the follow-up period.In conclusion fluoroquinolone-macrolide therapy resulted in pathogen eradication and CBP symptom attenuation,including pain,voiding disturbances and sexual dysfunction.A once-daily 750-mg dose of ciprofloxacin for 4 weeks showed enhanced eradication rates and lower inflammatory white blood cell counts compared to the 500-mg dose for 6 weeks.Our results are open to further prospective validation.

  20. Sexually dimorphic serotonergic dysfunction in a mouse model of Huntington's disease and depression.

    Directory of Open Access Journals (Sweden)

    Thibault Renoir

    Full Text Available Depression is the most common psychiatric disorder in Huntington's disease (HD patients. In the general population, women are more prone to develop depression and such susceptibility might be related to serotonergic dysregulation. There is yet to be a study of sexual dimorphism in the development and presentation of depression in HD patients. We investigated whether 8-week-old male and female R6/1 transgenic HD mice display depressive-like endophenotypes associated with serotonergic impairments. We also studied the behavioral effects of acute treatment with sertraline. We found that only female HD mice exhibited a decreased preference for saccharin as well as impaired emotionality-related behaviors when assessed on the novelty-suppressed feeding test (NSFT and the forced-swimming test (FST. The exaggerated immobility time displayed by female HD in the FST was reduced by acute administration of sertraline. We also report an increased response to the 5-HT(1A receptor agonist 8-OH-DPAT in inducing hypothermia and a decreased 5-HT(2A receptor function in HD animals. While tissue levels of serotonin were reduced in both male and female HD mice, we found that serotonin concentration and hydroxylase-2 (TPH2 mRNA levels were higher in the hippocampus of males compared to female animals. Finally, the antidepressant-like effects of sertraline in the FST were blunted in male HD animals. This study reveals sex-specific depressive-related behaviors during an early stage of HD prior to any cognitive and motor deficits. Our data suggest a crucial role for disrupted serotonin signaling in mediating the sexually dimorphic depression-like phenotype in HD mice.

  1. An approach to symptoms at the interface of medicine and psychiatry: pain, insomnia, weight loss and anorexia, fatigue and forgetfulness, and sexual dysfunction.

    Science.gov (United States)

    Freudenreich, Oliver; Kontos, Nicholas; Nejad, Shamim H; Gross, Anne F

    2010-11-01

    Primary care physicians commonly deal with patients who present with a somatic complaint for which no clear organic etiology can be found. This article discusses how a psychiatrist thinks about somatic symptoms (eg, pain, insomnia, weight loss and loss of appetite, fatigue and forgetfulness, sexual dysfunction) in a patient who might have depression. The management of a patient in whom no satisfactory medical or psychiatric diagnosis can be made is also reviewed briefly. PMID:20951279

  2. Depression,Antidepressants and Male Sexual Dysfunction%抑郁和抗抑郁药物与男性性功能障碍

    Institute of Scientific and Technical Information of China (English)

    李宏军

    2009-01-01

    抑郁、抗抑郁药物及男性性功能障碍三者关系密切,本文系统阐述了三者的相互关系,简要介绍了常用抗抑郁药物分类及其不良反应,重点论述了抑郁及抗抑郁药物对男性性功能的不良影响、抗抑郁药物治疗男性性功能障碍及注意事项,对男科临床工作有一定指导和借鉴意义.%Depression,antidepressants and male sexual dysfunction are closely correlated.This article aims to expound their complicated correlation and give a brief introduction to the classification and adverse effects of common antidepressants.focusing on the influences of depression and antidepressants on male sexual dysfunction,the treatment of male sexual dysfunction with antidepressants, and the points for attention in the medication,which might offer some guidance for the clinical practice in andrology.

  3. [Sexuality and urological diseases].

    Science.gov (United States)

    Droupy, Stéphane

    2014-10-01

    Patients with lower urinary tract symptoms related to benign prostatic hyperplasia (BPH) frequently suffer from sexual dysfunction (erectile dysfunction and ejaculatory dysfunction). Erectile dysfunction and premature ejaculation are two times more common in men with chronic pelvic pain/chronic prostatitis. All treatments of prostate cancer are responsible for sexual dysfunctions. Sexual disorders frequently appear during the management of infertile couples. Information and support should be offered to couples. Women with urinary incontinence also suffer frequently from coital incontinence. PMID:25201599

  4. Effects ofDracaena arborea (Dracaenaceae) on sexual dysfunction in 4 weeks hyperglycemic male rats

    Institute of Scientific and Technical Information of China (English)

    Wankeu-Nya M; Watcho P; Nguelefack TB; Carro-Juarez M; Tapondjou L; Kamanyi A

    2014-01-01

    Objective:To investigate the effects ofDracaena arborea(D. arborea) on the sexual behavior parameters in experienced type-1 diabetic rats.Methods:Aqueous and ethanol(100 and500 mg/kg respectively) extracts of dried root barks ofD. arborea, sildenafil citrate(1.44 mg/kg), trimethylamine-N-oxide(TMAO,20 mg/kg) and distilled water(10 mL/kg) were orally administered to4 weeks streptozotocin-induced diabetic rats.Mount latency and frequency (ML,MF), intromission latency and frequency(IL,IF) and post-ejaculatory interval(PEI) were measured by ejaculatory series during90 min once a week for4 weeks.Glycemia was determined at the beginning and at the end of the treatment.Results:D. arborea did not show any major antihyperglycemic effects.Compared to the control group, a significant(P<0.05-0.001) increase inMF andIF was noticed in rats treated with sildenafil citrate(89.71% and90.07% respectively), aqueous(500 mg/kg,88.08% and88.74% respectively) and ethanol(100 mg/kg;89.53% and89.17 respectively) extracts ofD. arborea after two weeks(series1) of treatment.ML,IL andPEI were significantly(P<0.05-0.001) decreased after4 weeks of daily treatment [sildenafil citrate(96.31, 96.31% and34.98%), andD. arborea aqueous500 mg/kg(94.33,94.33% and66.60%) and ethanol extracts100 mg/kg(96.98,97.08% and64.26%)].Conclusions:These aphrodisiac potentials of D. arborea in experienced diabetic rats could be due to the antioxidant and androgenic properties of phenols, flavonoids, saponins and sterols revealed in the plant extracts.

  5. Effects of aqueous extract ofCnestis ferruginea (Vahl ex De Cantolle) root on paroxetine-induced sexual dysfunction in male rats

    Institute of Scientific and Technical Information of China (English)

    Yakubu Musa Toyin; Nurudeen Quadri Olaide

    2012-01-01

    Objective:To determine the effects of the aqueous extract ofCnestis ferruginea root on paroxetine-induced sexual dysfunction in maleWistar rats.Methods:The extract (13,26 and52 mg/kg body weight) and the reference herbal drug,PowmaxM (7.14 mg/kg body weight) were administered orally to paroxetine-induced sexually impaired male rats, once daily for5 d and their sexual behaviour parameters were monitored and computed.Theserum hormones (testosterone, follicle stimulating and luteinizing hormones) were determined at the end of the exposure period.Results:Administration of paroxetine to sexually active male rats significantly (P<0.05) reduced the mount frequency (MF), intromission frequency (IF), and ejaculation frequency (EF), whereas mount latency (ML), intromission latency (IL), ejaculatory latency (EL) and post-ejaculatory interval (PEI) were increased.The extracts progressively reversed the trends ofMF,IF,EF,ML,IL,EL andPEI in the paroxetin-treated animals towards the control values throughout the exposure period.The sexual behaviour parameters compared well with thePowmaxM-treated animals but not comparable to the distilled water administered animals. In addition, all the doses of the extract elevated (P<0.05) the levels of serumLH andFSH and decreased testosterone contents.Conclusions:The aqueous extract ofCnestis ferruginea root at the doses of13,26 and52 mg/kg body weight restored sexual competence at least to a reasonable extent in sexually impaired/sluggish male rats with the highest dose producing the best efficacy. The results support the folkloric claim of the plant for the management of sexual disorder in males.

  6. Prevalência de disfunção sexual em dois grupos de mulheres de diferentes níveis socioeconômicos Prevalence of sexual dysfunction in two women groups of different socioeconomic status

    Directory of Open Access Journals (Sweden)

    Daniela Siqueira Prado

    2010-03-01

    ou escolaridade.PURPOSE: to identify if there is a difference in the prevalence of sexual dysfunction and in the sexual domain scores between a group of women attended at a public service and a group attended at a private service, and to investigate if there is an association between sexual dysfunction, family income and educational status. METHODS: transversal study including 201 sexually active women aged from 18 to 45 years, 90 of them from a public service and 111 from private services. We evaluated age, marital status, use of hormonal contraception, income and educational status, and all women were submitted to the Female Sexual Function Index (FSFI, an instrument for the evaluation of their sexuality. The Statistical Package for Social Sciences, version 15.0, was used for statistical analysis. The χ2 test was applied for categorical variables and the Student's t-test to independent samples. RESULTS: there was no significant difference regarding the prevalence of sexual dysfunction between groups (public versus private (20 and 23.4%, p=0.5, or concerning the domain scores, desire (3.9±1.3 and 3.8±1.0, p=0.6, sexual arousal (4.5±0.8 and 4.4±0.9, p=0.5, lubrication (5.2±1.2 and 5.0±0.9, p=0.1, orgasm (5.0±1.2 and 4.9±1.1, p=0.5, satisfaction (5.2±1.2 and 5.1±1.0, p=0.9, and pain (5.3±1.1 and 5.2±1.0, p=0.8. Sexual dysfunction was detected in 28% of the women with income between two and four minimum wages, in 17.5% of those with an income of five wages or more, and in 14.3% among those with an income of one wage or less (p=0,1. The dysfunction occurred in 30.2% of women with elementary education, in 24.2% of those with high school education and in 13.4% of those with higher education (p=0.09. CONCLUSIONS: There was no significant difference in the prevalence of sexual dysfunction or in the sexual domain scores between groups, nor was there an association with income or education status.

  7. Prevention of antipsychotic-induced hyperglycaemia by vitamin D: a data mining prediction followed by experimental exploration of the molecular mechanism.

    Science.gov (United States)

    Nagashima, Takuya; Shirakawa, Hisashi; Nakagawa, Takayuki; Kaneko, Shuji

    2016-01-01

    Atypical antipsychotics are associated with an increased risk of hyperglycaemia, thus limiting their clinical use. This study focused on finding the molecular mechanism underlying antipsychotic-induced hyperglycaemia. First, we searched for drug combinations in the FDA Adverse Event Reporting System (FAERS) database wherein a coexisting drug reduced the hyperglycaemia risk of atypical antipsychotics, and found that a combination with vitamin D analogues significantly decreased the occurrence of quetiapine-induced adverse events relating diabetes mellitus in FAERS. Experimental validation using mice revealed that quetiapine acutely caused insulin resistance, which was mitigated by dietary supplementation with cholecalciferol. Further database analysis of the relevant signalling pathway and gene expression predicted quetiapine-induced downregulation of Pik3r1, a critical gene acting downstream of insulin receptor. Focusing on the phosphatidylinositol 3-kinase (PI3K) signalling pathway, we found that the reduced expression of Pik3r1 mRNA was reversed by cholecalciferol supplementation in skeletal muscle, and that insulin-stimulated glucose uptake into C2C12 myotube was inhibited in the presence of quetiapine, which was reversed by concomitant calcitriol in a PI3K-dependent manner. Taken together, these results suggest that vitamin D coadministration prevents antipsychotic-induced hyperglycaemia and insulin resistance by upregulation of PI3K function. PMID:27199286

  8. Healthy Sexuality

    Medline Plus

    Full Text Available ... over the course of a lifetime. The World Health Organization has defined sexual health as “…a state of physical, emotional, mental and ... the absence of disease, dysfunction, or infirmity. Sexual health requires a positive and respectful approach to sexuality ...

  9. 催眠治疗吸毒患者性功能障碍一例报告%Hypnosis to treat drug addicts case reports of sexual dysfunction

    Institute of Scientific and Technical Information of China (English)

    龚建南; 刘玉芳

    2014-01-01

    Objective:Enhancedmethadoneoutpatientrehabilitationmotivation,reducepsychologicaldependenceondrugs. Methods:Treatment with hypnosis new group withdrawal reactions and sexual dysfunction.Results:Withdrawal reaction is lighter, mood,sexual function,social function recovery.During 5 years tracking,personal integrity is good.Conclusion:Drug addicts’sexual dysfunction can’t rule out the influence of psychological factors.Psychological treatment to the patient’s recent treatment and long-term follow-up are very role.%目的:增强美沙酮门诊病人戒毒动机,减少对毒品的心理依赖。方法:用催眠术治疗新入组病人戒断反应和性功能障碍。结果:戒断反应较轻,情绪改善,性功能恢复,社会功能恢复。5年追踪,操守良好。结论:吸毒者性功能障碍不能排除心理因素的影响。心理治疗对病人的近期疗和远期疗效都有很作用。

  10. 抗抑郁药物致性功能障碍的临床研究进展%Clinical Research Progress of Antidepressant Drugs Causing Sexual Dysfunction

    Institute of Scientific and Technical Information of China (English)

    林国华(综述); 江回春(审校)

    2016-01-01

    Antidepressants not only has the antidepressant and anxiolytic clinical effects , but also adverse reactions.General adverse antidepressant effects can be divided into central and peripheral side effects,where the influence of antidepressants on sexual function belongs to peripheral side effects .Antide-pressant drugs causing sexual dysfunction has become a consensus.Therefore,when selecting antidepressant, the adverse effect on sexual function should be taken into account,and the patient′s sexual function change after medication should be inquired ,so as to develop individualized treatment program ..%抗抑郁药除了具有抗抑郁及抗焦虑的临床治疗作用外,同样具有不良反应。抗抑郁药物的不良反应一般可分为中枢性不良反应和外周性不良反应。其中抗抑郁药物对患者性功能的影响属于外周性不良反应。抗抑郁药物会引起性功能障碍已成为共识。因此,在选择抗抑郁药物时应考虑到性功能方面的不良反应,了解患者服药后性功能的变化,以制订个性化的处理方案。

  11. Genitourinary dysfunction in Parkinson's disease.

    Science.gov (United States)

    Sakakibara, Ryuji; Uchiyama, Tomoyuki; Yamanishi, Tomonori; Kishi, Masahiko

    2010-01-15

    Bladder dysfunction (urinary urgency/frequency) and sexual dysfunction (erectile dysfunction) are common nonmotor disorders in Parkinson's disease (PD). In contrast to motor disorders, genitourinary autonomic dysfunctions are often nonresponsive to levodopa treatment. The brain pathology causing the bladder dysfunction (appearance of overactivity) involves an altered dopamine-basal ganglia circuit, which normally suppresses the micturition reflex. By contrast, hypothalamic dysfunction is mostly responsible for the sexual dysfunction (decrease in libido and erection) in PD, via altered dopamine-oxytocin pathways, which normally promote libido and erection. The pathophysiology of the genitourinary dysfunction in PD differs from that in multiple system atrophy; therefore, it might aid in differential diagnosis. Anticholinergic agents are used to treat bladder dysfunction in PD, although these drugs should be used with caution particularly in elderly patients who have cognitive decline. Phosphodiesterase inhibitors are used to treat sexual dysfunction in PD. These treatments might be beneficial in maximizing the patients' quality of life. PMID:20077468

  12. Female Sexual Dysfunction

    Science.gov (United States)

    ... what’s going on. Sometimes a better line of communication is all that is needed. If necessary, you may want to get counseling, by yourself or with your partner. Sex therapy, usually a later step in the process, ...

  13. Current Issues in the Evaluation and Treatment of Sexual Disturbance.

    Science.gov (United States)

    Beutler, Larry E.

    1986-01-01

    Discusses causes of sexual disturbance, assessment of sexual dysfunction, treatment of sexual dysfunction, psychological issues associated with chronic physical illness and sexual behavior, theory and treatment in child molestation, and the psychosocial outcomes of sex reassignment surgery. (BL)

  14. Los inhibidores de las fosfodiesterasas en el tratamiento de la disfunción sexual eréctil The inhibitors of the phosphodiesterases in treatment of erectile sexual dysfunction

    Directory of Open Access Journals (Sweden)

    Manuel Correa Jáuregui

    2010-12-01

    Full Text Available La disfunción sexual masculina impone una carga significativamente negativa en la salud, en las relaciones interpersonales, en la autoestima y en la calidad de vida de los que la padecen. Hasta finales de la década de los 80, el tratamiento se limitaba a la terapia psicosexual y a los implantes peneanos, y la causa se atribuía principalmente a factores psicológicos. El surgimiento de los inhibidores orales de fosfodiesterasa 5 con el lanzamiento del sildenafil (viagra en 1998, constituyó desde sus inicios una verdadera revolución y son ahora la primera elección del tratamiento en la disfunción eréctil, por ser bien tolerados, eficaces, no invasivos y con buenas tasas de respuesta.En el siguiente artículo se realizó una revisión del uso de los inhibidores de las fosfodiesterasas en el tratamiento de la disfunción sexual eréctil, así como las características relevantes de los medicamentos más usados en la actualidad, lo que contribuirá al conocimiento y a su mejor prescripción. Con este objetivo se consultaron los trabajos más actuales publicados en Pubmed y Medline. Los inhibidores de las fosfodiesterasa (sildenafil, vardenafil y tadalafil constituyen los medicamentos de elección en el tratamiento de la disfunción eréctil por su probada eficacia, seguridad y tolerancia.The male sexual dysfunction imposes a significantly negative burden in health, in the interpersonal relations, in self-esteem, and the quality of life of those suffering it. Up to at the end of the 80 decade, treatment was limited to psychosexual therapy and to penile implants and the cause was due to mainly to psychological factors. The appearance of oral inhibitors of phosphodiesterase-5 like the Sildenafil citrate (Viagra in1998, was from its onsets a real revolution and now are the first choice for treatment of erectile dysfunction because it is well tolerated, effective, non-invasive and with a good response rate. In present paper authors made a review

  15. Change to Either a Nonandrogenic or Androgenic Progestin-Containing Oral Contraceptive Preparation is Associated with Improved Sexual Function in Women with Oral Contraceptive-Associated Sexual Dysfunction

    DEFF Research Database (Denmark)

    Davis, Susan R; Bitzer, Johannes; Giraldi, Annamaria;

    2013-01-01

    It is a commonly held belief that combined oral contraceptive (COC) pills containing an androgenic progestin may be less likely to impair sexual function than COCs containing an anti-androgenic progestin.......It is a commonly held belief that combined oral contraceptive (COC) pills containing an androgenic progestin may be less likely to impair sexual function than COCs containing an anti-androgenic progestin....

  16. Disfunção sexual em pacientes com câncer do colo uterino avançado submetidas à radioterapia exclusiva Sexual dysfunction in patients with advanced cervical cancer submitted to exclusive radiotherapy

    Directory of Open Access Journals (Sweden)

    Bebiana Calisto Bernardo

    2007-02-01

    Full Text Available OBJETIVO: identificar disfunções sexuais em pacientes com câncer de colo uterino submetidas à radioterapia exclusiva pela técnica de braquiterapia de alta taxa de dose. MÉTODOS: foi realizado um estudo descritivo do tipo corte transversal no período de janeiro a junho de 2004. O estudo envolveu 71 pacientes selecionadas de acordo o perfil estabelecido e que vinham sendo seguidas no ambulatório de pélvis do Hospital do Câncer de Pernambuco. Os dados foram coletados a partir de um questionário estruturado, complementado por um exame ginecológico visando investigar queixas de disfunção sexual após a radioterapia. Foi utilizado o programa estatístico Epi-Info 6.04 para processamento e análise dos dados. A análise descritiva foi feita pela média, mediana, valores máximo e mínimo. Para análise bivariada foram realizados os testes de homogeneidade marginal e McNemar, considerando um nível de significância de 5%. RESULTADOS: das complicações ginecológicas identificadas, destacam-se fibrose, estenose e atrofia vaginais (98,6, 76,1 e 71,8% dos casos, respectivamente. As disfunções sexuais identificadas foram: frigidez e falta de lubrificação, de excitação e de orgasmo, que ocorreram em 76,1% dos casos, falta de libido em 40,8% e vaginismo em 5,6% dos casos. CONCLUSÕES: as disfunções sexuais são freqüentes em pacientes com câncer do colo uterino avançado tratadas com radioterapia exclusiva utilizando o protocolo de braquiterapia de alta taxa de dose. Atenção específica deve ser dada à anamnese sexual e ao exame ginecológico durante o acompanhamento destas pacientes.PURPOSE: to identify sexual dysfunctions in patients with cancer of the uterine cervix submitted to exclusive radiotherapy, using the high dose rate (HDR brachytherapy technique. METHODS: a descriptive transversal study from January to June of 2004. The study involved 71 selected patients who had been followed in the pelvis outpatient clinic from the

  17. Sexual Problems

    Medline Plus

    Full Text Available ... of sexual pain that include conditions of the penis, such as phimosis or a tight frenulum, and ... vestibulectomy. Penile implants are devices inserted inside the penis that allow men with erectile dysfunction to get ...

  18. Sexual Problems

    Medline Plus

    Full Text Available ... include hormone therapy, antidepressants, phosphodiesterase inhibitors, which are drugs often used for erectile dysfunction, and other medications. ... may improve sexual function. A group of antidepressant drugs called selective serotonin reuptake inhibitors, or SSRIs, often ...

  19. PREVALENCE OF SEXUAL DYSFUNCTION, INSOMNIA AND DETERIORATION OF THE QUALITY OF LIFE IN HYSTERECTOMYZED WOMEN (IN SPANISH)

    OpenAIRE

    Saavedra-Orozco Héctor; Monterrosa-Castro Álvaro; Caraballo-Olave Elida; Ulloque-Caamaño Liezel; Rincón-Niño Erika

    2014-01-01

    Introduction: the hysterectomy is a surgical procedure used for the treatment of uterine pathologies. It has been demonstrated that this procedure could affect negatively different fields and to impact the quality of life (QoL). Objective: to assess the sexual function, insomnia and the QoL in a group of hysterectomized women. Methods: cross-sectional study carried out with three validated scales: The short 6-item Female Sexual Function Index (FSFI-6), the Athens Insomnia Sc...

  20. 平凉市中老年男性性功能调查报告%Prevalence of aging male sexual dysfunction in Pingliang City

    Institute of Scientific and Technical Information of China (English)

    韩晓峰; 任江玲; 胡黎明; 许克新

    2011-01-01

    目的 调查平凉市中老年男性性欲低下、勃起功能障碍(erectile dysfunction,ED)、射精障碍的患病情况.方法 采用分层多阶段整群不等比例随机抽样方法,选择城区6个居委会和郊区20个行政村1539名年龄≥50岁男性作为调查对象,分别记录国际勃起功能问卷(IIEF-5)评分及男性性功能问卷(O'Leafy 1995)评分,应用χ2检验分析调查数据.结果 符合标准的调查对象1 230人,年龄50~89(62.5±9.6)岁.平均IIEF-5(9.4±8.6)分.以IIEF-5评分0~21分诊断为ED,总ED患病率92.27%,性欲低下57.96%,射精障碍36.91%.各年龄组间(10岁/组)ED、性欲低下、射精障碍患病率差异有统计学意义(P<0.0001),各年龄组间不同程度ED患病率差异有统计学意义(P<0.0001).结论 随年龄增加ED、性欲低下、射精障碍的患病率逐渐增加,ED患病率最高.%Objective To investigate the prevalence of aging male sexual dysfunction in Pingliang City, Gansu Province.MethodS A cross-sectional study was performed in 6 urban communities and 20 villages in the suburbs of Jingning County,with 1539 males aged over 50 enrolled. The International Index of Erectile Function-5 (IIEF-5) and Brief Male Scxual Function Inventory foi Urology (O' Leary 1995) were recorded and analyzed. Results 1230 subjects were included in the survey, average age (62. 5± 9. 6) years, ranging 50~89. The mean score of IIEF-5 was 9. 4± 8. 6. The prevalence of erectile dysfunction (ED) , defined as IIEF-5 between 0~21, was 92. 27% . The incidence of reduction of sexual desire and defective ejaculation was 57 . 96 % and 36 . 91% , respectively. There was positive correlation between the prevalence of ED. reduction of sexual desire, defective ejaculation and age. Conclusions The incidence of ED, reduction of sexual desire and defective ejaculation are positively correlated with age. And ED ranks the first among these sexual dysfunctions.

  1. Rosa damascena oil improves SSRI-induced sexual dysfunction in male patients suffering from major depressive disorders: results from a double-blind, randomized, and placebo-controlled clinical trial

    Directory of Open Access Journals (Sweden)

    Farnia V

    2015-03-01

    Full Text Available Vahid Farnia,1 Mehdi Shirzadifar,2 Jalal Shakeri,1 Mansour Rezaei,3 Hafez Bajoghli,4,5 Edith Holsboer-Trachsler,6 Serge Brand6,7 1Substance Abuse Prevention Research Center, Psychiatry Department, Kermanshah University of Medical Sciences, Kermanshah, Iran; 2Student Research Center, Psychiatry Department, Kermanshah University of Medical Sciences, Kermanshah, Iran; 3Department of Statistics and Epidemiology, Kermanshah University of Medical Sciences, Kermanshah, Iran; 4Iranian National Center for Addiction Studies, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran; 5ASEAN Institute for Health Development, Mahidol University, Nakhon Pathom, Thailand; 6Psychiatric Clinics of the Center for Affective, Stress and Sleep Disorders, Psychiatric Hospital of the University of Basel, Basel, Switzerland; 7Sport Science Section, Department of Sport, Exercise and Health, University of Basel, Basel, Switzerland Background: A substantial disadvantage of psychopharmacological treatment of major depressive disorder (MDD with selective serotonin-reuptake inhibitors (SSRIs is the impact on sexual dysfunction. The aim of the present study was to investigate whether the oil of Rosa damascena can have a positive influence on SSRI-induced sexual dysfunction (SSRI-I SD of male patients who are suffering from MDD and are being treated with SSRIs.Method: In a double-blind, randomized, and placebo-controlled clinical trial, a total of 60 male patients treated with an SSRI and suffering from MDD (mean age =32 years and SSRI-I SD were randomly assigned to take either verum (R. damascena oil or a placebo. Patients completed self-ratings of depression and sexual function at baseline, at 4 weeks later, and at the end of the study, 8 weeks after it started.Results: Over time, sexual dysfunction improved more in the verum group than in the control group. Improvements were observed in the verum group from week 4 to week

  2. Treinamento dos músculos do assoalho pélvico nas disfunções sexuais femininas Pelvic floor muscle training in female sexual dysfunctions

    Directory of Open Access Journals (Sweden)

    Virginia Pianessole Piassarolli

    2010-05-01

    Full Text Available OBJETIVO: avaliar o efeito do treinamento dos músculos do assoalho pélvico (TMAP sobre as disfunções sexuais femininas. MÉTODOS: para esse ensaio clínico com abordagem antes e depois, foram incluídas 26 mulheres que apresentavam diagnóstico de disfunção sexual (transtorno de desejo sexual, de excitação, orgástico e/ou dispareunia. As participantes foram avaliadas antes, na metade (após cinco sessões e ao final do tratamento (após dez sessões, por meio da palpação vaginal bidigital (avaliação da força dos músculos do assoalho pélvico-MAP, eletromiografia (EMG intravaginal (captação das amplitudes de contração dos MAP e Female Sexual Function Index (FSFI, questionário de avaliação da função sexual. As mulheres foram submetidas ao TMAP em diferentes posições, por dez sessões (uma ou duas vezes na semana. Para análise estatística, utilizou-se frequências absolutas e relativas para características clínicas e força dos MAP. Empregou-se teste de Friedman para comparação dos escores dos domínios do FSFI e valores da EMG, t de Student para associação entre esses valores e características das mulheres e Wilcoxon para modificação percentual da EMG. O teste Mann-Whitney permitiu comparar esses valores com características clínicas. Para correlacionar os valores da EMG com escore total médio, utilizou-se teste de correlação de Spearman. Adotou-se nível de significância de pPURPOSE: to evaluate the effect of pelvic floor muscle training (PFMT on female sexual dysfunctions. METHODS: twenty-six women with a diagnosis of sexual dysfunction (sexual desire, arousal, orgasmic disorders and/or dyspareunia were included in a clinical trial with a before/after approach . The assessment was carried out before, during (after five sessions and at the end of the treatment (after ten sessions by two-digit palpation (assessment of pelvic floor muscle, PFM, strength, intravaginal electromyography (EMG (capture of PFM

  3. Penile anesthesia in Post SSRI Sexual Dysfunction (PSSD) responds to low-power laser irradiation : a case study and hypothesis about the role of transient receptor potential (TRP) ion channels

    NARCIS (Netherlands)

    Waldinger, Marcel D; van Coevorden, Ruben S; Schweitzer, Dave H; Georgiadis, Janniko

    2015-01-01

    Treatment of paroxetine-induced penile anesthesia in Post SSRI Sexual Dysfunction (PSSD) by Low-power Laser Irradiation (LPLI) is unknown in medical literature. The aim of the current article is to report partial efficacy of LPLI for paroxetine-induced persistent penile anesthesia. We report on a ma

  4. Penile anesthesia in Post SSRI Sexual Dysfunction (PSSD) responds to low-power laser irradiation : A case study and hypothesis about the role of transient receptor potential (TRP) ion channels

    NARCIS (Netherlands)

    Waldinger, Marcel D.; van Coevorden, Ruben S.; Schweitzer, Dave H.; Georgiadis, Janniko

    2015-01-01

    Treatment of paroxetine-induced penile anesthesia in Post SSRI Sexual Dysfunction (PSSD) by Low-power Laser Irradiation (PLO is unknown in medical literature. The aim of the current article is to report partial efficacy of LPLI for paroxetine-induced persistent penile anesthesia. We report on a male

  5. Current approach to sexual disfunctions in women

    OpenAIRE

    Abdulkadir Tepeler; Levend Özkan; Hikmet Yaşar

    2010-01-01

    Even though sexual problems and sexual dysfunction are commonly observed in the society, a significant majority of the problems are not reported to the doctors, and due to this fact, remain unaddressed. In our country, the studies about sexual dysfunction are limited in number but in recent years there has been an increase in these studies. The ratio of sexual dysfunction is higher in women than the ratio in men (43%; 31%). However, there are few treatment modality about women sexual dysfunct...

  6. [Neurogenic erectile dysfunction].

    Science.gov (United States)

    Ramos, Antonio Sánchez; Durán, Juan Antonio Godino; Oliviero, Antonio

    2010-10-01

    Neurogenic erectile dysfunction is a consequence of alterations in neural pathways, autonomic, somatic, the combination of both or brain components that induce erection. This review aims to explain the physiopathological mechanisms of the most frequent neurological alterations causing erectile dysfunction and sexual disorders. PMID:20978292

  7. Female Sexual Dysfunction:Classification and Definitions%女性性功能障碍的分类及定义

    Institute of Scientific and Technical Information of China (English)

    廖秦平; 李婷

    2013-01-01

    女性性功能障碍(female sexual dysfunction,FSD)是一种十分常见的疾病,严重影响女性的身心健康.国际上常用的女性性功能障碍分类标准有世界卫生组织(WHO)的国际疾病和相关健康问题统计学分类-10(International Classifications of Diseases-10,ICD-10)、精神障碍诊断与统计学手册第4版和第5版(The Diagnostic and Statistical Manual of Mental Disorders-Ⅳ~Ⅴ,DSM-Ⅳ~Ⅴ)和国际专家认可的女性性功能障碍分类(The Consensus-based Classification of Female Sexual Dysfunction,CCFSD)等多个命名系统.这些命名系统均基于性反应周期的线性模型,将FSD分为4大类:性欲障碍、性唤起障碍、性高潮障碍和性交疼痛障碍.ICD-10、DSM-Ⅳ~Ⅴ和CCFSD命名系统及诊断标准随着人们对女性性功能障碍认识的不断深入和临床经验的不断积累而逐渐完善.然而,由于女性性反应十分复杂,这些命名系统均存在一定的缺陷,故需要进一步统一明确FSD的分类,完善FSD定义及诊断标准.

  8. Disfunción sexual asociada al uso de gabapentina en el tratamiento del dolor central Associated sexual dysfunction to the use of gabapentin in the treatment of the central pain

    Directory of Open Access Journals (Sweden)

    E. Calderón

    2006-06-01

    Full Text Available El dolor neuropático de origen central es uno de los síndromes dolorosos más complejos, su tratamiento es difícil y, en general, poco satisfactorio. Gabapentina (GBP es un anticonvulsivante usado en el tratamiento de la epilepsia, dolor neuropático, desórdenes bipolares, y es generalmente bien tolerado. Los anticonvulsivantes de segunda generación cuentan entre sus ventajas con una menor incidencia de efectos secundarios. No obstante, estamos hablando de fármacos relativamente nuevos, sobre todo para su utilización al margen de los trastornos no epilépticos, como es el caso del dolor neuropático, por lo que es necesario un estudio y seguimiento más completo de sus posibles efectos secundarios. Presentamos 2 casos de disfunción sexual en hombre y mujer en relación con la administración de gabapentina para control del dolor de origen central. El aumento de la concentración de serotonina podría ser la causa de las alteraciones sexuales relacionadas con el tratamiento con GBP a las dosis utilizadas en nuestros pacientes, superiores a 1.800 mg/día. Este efecto es dosis-dependiente y el tratamiento consiste en disminuir o ajustar la dosis para maximizar el intervalo de tiempo entre la toma previa y el acto sexual.The neuropathic central pain, is one of the more complex painful syndromes, its treatment is difficult and, in general, little satisfactory. Gabapentin (GBP, it is a anticon-vulsant used in the treatment of the epilepsy, neuropathic pain, disorder bipolar, and it is generally well tolerated The anticonvulsants of second generation count between their advantages with a smaller incidence of secondary effects. However, we are considering of relatively new drugs, mainly for its use to the margin of epilepsy, as it is the case of the neuropathic pain. For this reason it is necessary a study and more complete pursuit of its possible secondary effects. We presented 2 cases of sexual dysfunction in a man and a woman in relation to

  9. Idade e distúrbios psicológicos: variáveis associadas à disfunção sexual no período pós-infarto Age and psychologic disorders: variables associated to post-infarction sexual dysfunction

    Directory of Open Access Journals (Sweden)

    Luciano Janussi Vacanti

    2005-08-01

    Full Text Available OBJETIVO: As informações sobre a disfunção sexual (DS após o infarto do miocárdio (IM são esparsas, principalmente em nosso meio e em relação aos seus preditores. Avaliamos pacientes de ambos os sexos, com vida sexual ativa e sem disfunção sexual prévia ao IM, para estudar a incidência de DS após o IM, e identificar as possíveis variáveis associadas às mesmas. MÉTODOS: Estudamos consecutivamente 43 pacientes, utilizando questionários estruturados para diagnóstico das DS e dos distúrbios psicológicos (DP. Analisamos a influência dos fatores de risco clássicos para aterosclerose, dos DP e do uso de medicamentos na ocorrência de DS até o sexto mês após o IM. RESULTADOS: Após o IM, 91% dos pacientes reiniciaram a atividade sexual. Vinte e seis pacientes (60% apresentaram disfunção sexual até o 6º mês da alta hospitalar (9 com ejaculação precoce, 15 com disfunção erétil e 20 com desejo sexual hipoativo. Os pacientes com DP apresentaram disfunção sexual em maior freqüência que aqueles sem DP (100%x47%, p=0,001. O grupo com disfunção sexual era significativamente mais velho que o grupo sem disfunção sexual: 53±8,9 anos versus 47±8,7 anos (p=0,04. CONCLUSÃO: Os pacientes apresentaram significativa redução da freqüência da atividade sexual e elevada incidência de DS após o infarto agudo do miocárdio. A presença de DP e a idade mais elevada estiveram associadas à maior incidência de DS após o infarto.OBJECTIVE: Data on sexual disfunction (SD after myocardial infarction (MI are sketchy, especially in our community and in regard to predictors. Both males and females, with active sexual life and no sexual dysfunction prior to MI were evaluated in order to investigate SD incidence after MI, as well as to identify the possible variables associated. METHODS: Forty-three patients were studied consecutively, through structured questionnaires for SD and psychological disorders (PD diagnosis. The

  10. Stress affects a gastrin-releasing peptide system in the spinal cord that mediates sexual function: implications for psychogenic erectile dysfunction.

    Directory of Open Access Journals (Sweden)

    Hirotaka Sakamoto

    Full Text Available BACKGROUND: Many men suffering from stress, including post-traumatic stress disorder (PTSD, report sexual dysfunction, which is traditionally treated via psychological counseling. Recently, we identified a gastrin-releasing peptide (GRP system in the lumbar spinal cord that is a primary mediator for male reproductive functions. METHODOLOGY/PRINCIPAL FINDINGS: To ask whether an acute severe stress could alter the male specific GRP system, we used a single-prolonged stress (SPS, a putative rat model for PTSD in the present study. Exposure of SPS to male rats decreases both the local content and axonal distribution of GRP in the lower lumbar spinal cord and results in an attenuation of penile reflexes in vivo. Remarkably, pharmacological stimulation of GRP receptors restores penile reflexes in SPS-exposed males, and induces spontaneous ejaculation in a dose-dependent manner. Furthermore, although the level of plasma testosterone is normal 7 days after SPS exposure, we found a significant decrease in the expression of androgen receptor protein in this spinal center. CONCLUSIONS/SIGNIFICANCE: We conclude that the spinal GRP system appears to be a stress-vulnerable center for male reproductive functions, which may provide new insight into a clinical target for the treatment of erectile dysfunction triggered by stress and psychiatric disorders.

  11. A Streetcar Named "Derousal"? A Psychophysiological Examination of the Desire-Arousal Distinction in Sexually Functional and Dysfunctional Women.

    Science.gov (United States)

    Sarin, Sabina; Amsel, Rhonda; Binik, Yitzchak M

    2016-01-01

    Research indicates that desire and arousal problems are highly interrelated in women. Therefore, hypoactive sexual desire disorder (HSDD) and female sexual arousal disorder (FSAD) were removed from the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), and a new diagnostic category, female sexual interest/arousal disorder (FSIAD), was created to include both arousal and desire difficulties. However, no research has tried to distinguish these problems based on psychosocial-physiological patterns to identify whether unique profiles exist. This study compared psychosocial-physiological patterns in a community sample of 84 women meeting DSM-IV (American Psychiatric Association, 2000 ) criteria for HSDD (n = 22), FSAD (n = 18), both disorders (FSAD/HSDD; n = 25), and healthy controls (n = 19). Women completed self-report measures and watched neutral and erotic films while genital arousal (GA) and subjective arousal (SA) were measured. Results indicated that GA increased equally for all groups during the erotic condition, whereas women with HSDD and FSAD/HSDD reported less SA than controls or FSAD women. Women in the clinical groups also showed lower concordance and greater impairment on psychosocial variables as compared to controls, with women with FSAD/HSDD showing lowest functioning. Results have important implications for the classification and treatment of these difficulties. PMID:26457746

  12. Disfunção erétil: resultados do estudo da vida sexual do brasileiro Erectile dysfunction: results of the Brazilian sexual life study

    Directory of Open Access Journals (Sweden)

    Carmita Helena Najjar Abdo

    2006-12-01

    Full Text Available OBJETIVO: Estimar a prevalência da disfunção erétil (DE e fatores de risco associados em amostra da população brasileira. MÉTODOS: Estudo transversal com amostra de conveniência de 2.862 homens, maiores de 18 anos, por meio de questionário anônimo e auto-responsivo. A prevalência de DE na amostra foi obtida mediante questão global derivada diretamente da definição de DE. Os dados foram submetidos a testes Qui-quadrado e t de Student. Foram utilizadas análises de regressão logística para cálculos dos riscos. RESULTADOS: A prevalência encontrada de DE foi 45,1% (31,2% mínima, 12,2% moderada e 1,7% completa. Indivíduos com DE apresentaram comprometimento da auto-estima, dos relacionamentos interpessoais, menos relações sexuais por semana, mais relações extraconjugais, queixas de falta de desejo sexual e ejaculação rápida. Comparados aos homens com idades entre 18 e 39 anos, aqueles com 60 a 69 têm 2,2 (95% IC; 1,4-3,4; p OBJETIVE: To estimate the prevalence of ED and related risk factors in a sample of the Brazilian male population. METHODS: Cross-sectional study was carried out with a convenience sample of 2,862 men, 18 years of age or older, using an anonymous self-administered questionnaire. ED prevalence in the sample was obtained by a general question which was directly derived from the ED definition. Data were submitted to chi-square or Student's t tests. Logistic regression analyses were used for risk factor calculations. RESULTS: The prevalence of ED was 45.1% (31.2% mild, 12.2% moderate and 1.7% complete. Subjects with ED presented lower self-esteem, hindered interpersonal relationships, fewer sexual intercourses per week, more extra-marital relationships, complaints of lack of libido and premature ejaculation. When compared with men aged 18-39 years, men aged 60-69 presented 2.2 higher risk of ED (95% CI; 1.4-3.4; p < 0.01, whereas men aged 70 or older presented 3.0 higher risk of ED (95% CI; 1.4-6.3; p < 0

  13. The correlation between emotional distress and aging males’ symptoms at a psychiatric outpatient clinic: sexual dysfunction as a distinguishing characteristic between andropause and anxiety/depression in aging men

    Directory of Open Access Journals (Sweden)

    Chen CY

    2013-06-01

    Full Text Available Ching-Yen Chen,1,4,5 Chin-Pang Lee,1,4 Yu Chen,2,4,5 Jun-Ran Jiang,3,4,5 Chun-Lin Chu,1,4,5 Chun-Liang Chen3,4,5 1Department of Psychiatry, 2Department of Urology, 3Department of Traditional Chinese Medicine, 4Men’s Health Center, Chang Gung Memorial Hospital at Linkou, Taiwan; 5School of Medicine, Chang Gung University, Taoyuan, Taiwan Background: Andropause and psychiatric disorders are associated with various symptoms in aging males and are part of the differential diagnosis of depression and anxiety. This study was designed to investigate the relationship between symptoms of aging, anxiety, and depression, and to determine if sexual dysfunction could be a differentiating characteristic in the psychiatric outpatient clinic. Methods: One hundred seventy-six male psychiatric outpatients participated in the study and completed self-reported measures assessing symptoms of aging, depression, and anxiety. Symptoms of aging were assessed by the Aging Males’ Symptoms scale. Anxiety and depression were measured by the Hospital Anxiety and Depression Scale. Erectile dysfunction was considered if a response to item 15 on the Aging Males’ Symptoms scale (impaired sexual potency was rated with 4 or 5 points. Affective disturbance was assessed by the total scores of the Hospital Anxiety and Depression Scale. Results: Age was correlated with less anxiety and more sexual symptoms. Anxiety and depression were associated with more severe symptoms of aging, and depression was associated with more sexual symptoms than was anxiety. Impaired sexual potency was the only sexual symptom not significantly associated with depression and anxiety. Depression was associated with an interspousal age gap of ≥6 years. The point prevalence of erectile dysfunction was 28.4%, and age and affective disturbance were associated with the risk of erectile dysfunction. Conclusion: Impaired sexual potency should raise the suspicion of androgen deficiency rather than depression

  14. Sexual Abuse and Sexual Functioning in a Chronic Pelvic Pain Sample

    Science.gov (United States)

    Randolph, Mary E.; Reddy, Diane M.

    2006-01-01

    Sexual abuse, particularly childhood sexual abuse, has been linked to chronic pelvic pain and to sexual dysfunction, though the sexual functioning of survivors of sexual abuse has not been studied in a chronic pain population. Sixty-three women with chronic pelvic pain completed measures of sexual function, sexual abuse, and pain. Using an index…

  15. The correlation between emotional distress and aging males’ symptoms at a psychiatric outpatient clinic: sexual dysfunction as a distinguishing characteristic between andropause and anxiety/depression in aging men

    OpenAIRE

    Chen, Ching-Yen; Lee, Chin-Pang; Chen, Yu; Jiang, Jun-Ran; Chu, Chun-Lin; Chen, Chun-Liang

    2013-01-01

    Background Andropause and psychiatric disorders are associated with various symptoms in aging males and are part of the differential diagnosis of depression and anxiety. This study was designed to investigate the relationship between symptoms of aging, anxiety, and depression, and to determine if sexual dysfunction could be a differentiating characteristic in the psychiatric outpatient clinic. Methods One hundred seventy-six male psychiatric outpatients participated in the study and completed...

  16. Sexuality Following Radical Prostatectomy

    DEFF Research Database (Denmark)

    Fode, Mikkel; Serefoglu, Ege C; Albersen, Maarten;

    2016-01-01

    INTRODUCTION: Radical prostatectomies can result in urinary incontinence and sexual dysfunction. Traditionally, these issues have been studied separately, and the sexual problem that has received the most focus has been erectile dysfunction. AIM: To summarize the literature on sexually related side...... effects and their consequences after radical prostatectomy and focus on the occurrence and management of problems beyond erectile dysfunction. METHODS: The literature on sexuality after radical prostatectomy was reviewed through a Medline search. Original research using quantitative and qualitative...... methodologies was considered. Priority was given to studies exploring aspects of sexuality other than erectile function. MAIN OUTCOME MEASURES: The prevalence, predictive factors, and management of post-prostatectomy sexual problems beyond erectile dysfunction. RESULTS: Most patients will develop urinary...

  17. Hypoactive sexual desire disorder caused by antiepileptic drugs

    Directory of Open Access Journals (Sweden)

    M Singh

    2015-01-01

    Full Text Available Female sexual dysfunction is common but poorly understood sexual problem in women. Sexual dysfunction in female is multi-factorial in origin and also observed with intake of drug acting on central nervous system. This case report describes a female epileptic patient who developed sexual dysfunction with intake of antiepileptic drugs.

  18. Hypoactive sexual desire disorder caused by antiepileptic drugs

    OpenAIRE

    M Singh; Manish Bathla; Martin, A. (Alan); Aneja, J.

    2015-01-01

    Female sexual dysfunction is common but poorly understood sexual problem in women. Sexual dysfunction in female is multi-factorial in origin and also observed with intake of drug acting on central nervous system. This case report describes a female epileptic patient who developed sexual dysfunction with intake of antiepileptic drugs.

  19. Clinical trial of sexual dysfunctions in male patients with pituitary adenomas%垂体腺瘤男性患者性功能障碍的临床观察

    Institute of Scientific and Technical Information of China (English)

    周任远; 王国民; 张跃辉; 施国伟; 何家扬; 蒋为众; 李士其

    2012-01-01

    Objective To explore the clinical features and related factors of sexual dysfunctions in male patients with pituitary adenomas.Methods The questionnaires of sexual functions were collected from 86 male patients with pituitary adenomas. We examined the clinical features of sexual dysfunctions and analyzed the correlations between sexual behaviors and age,tumor type,invasiveness,tumor size,serum levels of prolactin (PRL) and testosterone.Results The incidence of sexual dysfunctions was 80.2% (69/86).Sexual dysfunctions were found in 84.6% (66/78) of the patients with functioning pituitary adenomas and 37.5% (3/8) of those with non-functioning pituitary adenoma respectively.In the PRL group,the incidence of erectile dysfunctions was 92.1% (35/38) and it was higher than those in the FSH (folliclestimulating hormone) and GH (growth hormone) groups (P < 0.05).In the FSH group,the incidence of reduced sexual desire was 78.3% (18/23).In the GH group,the incidence of erectile dysfunctions was 70.6% ( 12/17 ) and the incidence of reduced sexual desire or ejaculation dysfunction was lower than that of the PRL/FSH group (P < 0.05).Conclusion The incidence of sexual dysfunctions is quite high in males with pituitary adenomas,especially for those with functioning pituitary adenomas.The clinical features of sexual dysfunctions vary in different types of functioning pituitary adenoma. The incidence of erectile dysfunctions is the highest in the PRL group.Pathological type of pituitary tumors is a major risk factor of sexual dysfunctions.%目的 了解垂体腺瘤男性患者性功能障碍(SD)的发病特征和影响因素.方法 回顾性调查和分析86例男性垂体腺瘤患者术前性功能情况,总结不同类型垂体腺瘤男性患者SD的发病特征,分析SD与年龄、肿瘤类型、侵袭性、大小、血泌乳素水平和睾酮水平的相关性.结果 垂体腺瘤男性患者SD的发生率为80.2%( 69/86).其中,功能性垂

  20. Alga Ecklonia bicyclis, Tribulus terrestris, and glucosamine oligosaccharide improve erectile function, sexual quality of life, and ejaculation function in patients with moderate mild-moderate erectile dysfunction: a prospective, randomized, placebo-controlled, single-blinded study.

    Science.gov (United States)

    Sansalone, Salvatore; Leonardi, Rosario; Antonini, Gabriele; Vitarelli, Antonio; Vespasiani, Giuseppe; Basic, Dragoslav; Morgia, Giuseppe; Cimino, Sebastiano; Russo, Giorgio Ivan

    2014-01-01

    We aimed to evaluate the efficacy of oral therapy with alga Ecklonia bicyclis, Tribulus terrestris, and glucosamine oligosaccharide (Tradamix TX1000) in patients with erectile dysfunction (ED) at 3 months of follow-up. From January 2013 to September 2013, 177 patients diagnosed with mild-moderate ED (IIEF-EF < 26) were enrolled in this multicenter, single-blinded, placebo-controlled study and randomized in Group A (Tradamix, n = 87) and Group B (placebo, n = 90). Penile color Doppler ultrasound measures, IIEF-15 questionnaire, male sexual health questionnaire-ejaculation disorder (MSHQ-EjD), and sexual quality of life (SQoL-M) were collected. We observed significant changes of the IIEF-15 in Group A (mean difference: 11.54; P < 0.05) at 3 months versus Group B (P < 0.05). PSV (P < 0.05), IIEF-intercourse satisfaction (P < 0.05), IIEF-orgasmic function (mean P < 0.05), IIEF-sexual desire (P < 0.05), IIEF-overall satisfaction (P < 0.05), MSHQ-EjD (mean difference: 1.21; P < 0.05), and SQoL-M (mean difference: 10.2; P < 0.05) were significantly changed in Group A versus baseline and Group B. Patients with moderate arterial dysfunction showed significant increase of PSV (P < 0.05), IIEF-EF (P < 0.05), MSHQ-EjD (P < 0.05), and SQoL-M (P < 0.05) in Group A. Therapy with Tradamix improves erectile and ejaculation function and sexual quality of life in patients with mild-moderate ED and in particular for those with moderate arterial dysfunction. PMID:25136552

  1. Alga Ecklonia bicyclis, Tribulus terrestris, and Glucosamine Oligosaccharide Improve Erectile Function, Sexual Quality of Life, and Ejaculation Function in Patients with Moderate Mild-Moderate Erectile Dysfunction: A Prospective, Randomized, Placebo-Controlled, Single-Blinded Study

    Science.gov (United States)

    Sansalone, Salvatore; Leonardi, Rosario; Antonini, Gabriele; Vitarelli, Antonio; Vespasiani, Giuseppe

    2014-01-01

    We aimed to evaluate the efficacy of oral therapy with alga Ecklonia bicyclis, Tribulus terrestris, and glucosamine oligosaccharide (Tradamix TX1000) in patients with erectile dysfunction (ED) at 3 months of follow-up. From January 2013 to September 2013, 177 patients diagnosed with mild-moderate ED (IIEF-EF < 26) were enrolled in this multicenter, single-blinded, placebo-controlled study and randomized in Group A (Tradamix, n = 87) and Group B (placebo, n = 90). Penile color Doppler ultrasound measures, IIEF-15 questionnaire, male sexual health questionnaire-ejaculation disorder (MSHQ-EjD), and sexual quality of life (SQoL-M) were collected. We observed significant changes of the IIEF-15 in Group A (mean difference: 11.54; P < 0.05) at 3 months versus Group B (P < 0.05). PSV (P < 0.05), IIEF-intercourse satisfaction (P < 0.05), IIEF-orgasmic function (mean P < 0.05), IIEF-sexual desire (P < 0.05), IIEF-overall satisfaction (P < 0.05), MSHQ-EjD (mean difference: 1.21; P < 0.05), and SQoL-M (mean difference: 10.2; P < 0.05) were significantly changed in Group A versus baseline and Group B. Patients with moderate arterial dysfunction showed significant increase of PSV (P < 0.05), IIEF-EF (P < 0.05), MSHQ-EjD (P < 0.05), and SQoL-M (P < 0.05) in Group A. Therapy with Tradamix improves erectile and ejaculation function and sexual quality of life in patients with mild-moderate ED and in particular for those with moderate arterial dysfunction. PMID:25136552

  2. Alga Ecklonia bicyclis, Tribulus terrestris, and Glucosamine Oligosaccharide Improve Erectile Function, Sexual Quality of Life, and Ejaculation Function in Patients with Moderate Mild-Moderate Erectile Dysfunction: A Prospective, Randomized, Placebo-Controlled, Single-Blinded Study

    Directory of Open Access Journals (Sweden)

    Salvatore Sansalone

    2014-01-01

    Full Text Available We aimed to evaluate the efficacy of oral therapy with alga Ecklonia bicyclis, Tribulus terrestris, and glucosamine oligosaccharide (Tradamix TX1000 in patients with erectile dysfunction (ED at 3 months of follow-up. From January 2013 to September 2013, 177 patients diagnosed with mild-moderate ED (IIEF-EF < 26 were enrolled in this multicenter, single-blinded, placebo-controlled study and randomized in Group A (Tradamix, n=87 and Group B (placebo, n=90. Penile color Doppler ultrasound measures, IIEF-15 questionnaire, male sexual health questionnaire-ejaculation disorder (MSHQ-EjD, and sexual quality of life (SQoL-M were collected. We observed significant changes of the IIEF-15 in Group A (mean difference: 11.54; P<0.05 at 3 months versus Group B (P<0.05. PSV (P<0.05, IIEF-intercourse satisfaction (P<0.05, IIEF-orgasmic function (mean P<0.05, IIEF-sexual desire (P<0.05, IIEF-overall satisfaction (P<0.05, MSHQ-EjD (mean difference: 1.21; P<0.05, and SQoL-M (mean difference: 10.2; P<0.05 were significantly changed in Group A versus baseline and Group B. Patients with moderate arterial dysfunction showed significant increase of PSV (P<0.05, IIEF-EF (P<0.05, MSHQ-EjD (P<0.05, and SQoL-M (P<0.05 in Group A. Therapy with Tradamix improves erectile and ejaculation function and sexual quality of life in patients with mild-moderate ED and in particular for those with moderate arterial dysfunction.

  3. Human Sexual Desire Disorder: Do We Have a Problem?

    Science.gov (United States)

    McNab, Warren L.; Henry, Jean

    2006-01-01

    Hypoactive Sexual Desire Disorder (HSDD), loss of sexual desire for sexual activity, is one of the most common sexual dysfunctions of men and women in the United States. This article presents an overview of this specific sexual dysfunction including incidence, possible causes, treatment options, and the role of the health educator in addressing…

  4. Sexuality research in India: An update

    OpenAIRE

    Prakash, Om; Rao, T. S. Sathyanarayana

    2010-01-01

    This review provides the available evidence on sexual dysfunctions in India. Most of the studies have concentrated on male sexual dysfunction and hardly a few have voiced the sexual problems in females. Erectile dysfunction (ED), premature ejaculation (PME) and combinations of ED and PME appear to be main dysfunctions reported in males. Dhat syndrome remains an important diagnosis reported in studies from North India. There is a paucity of literature on management issues with an emergent need...

  5. Female Genital Dialogues: Female Genital Self-Image, Sexual Dysfunction, and Quality of Life in Patients With Vitiligo With and Without Genital Affection.

    Science.gov (United States)

    Sarhan, Deena; Mohammed, Ghada F A; Gomaa, Amal H A; Eyada, Moustafa M K

    2016-04-01

    Vitiligo has a major effect on sexual health because of the disfiguring skin lesions affecting self-image and self-esteem. However, this topic has not explored. This article aimed to assess the effect of vitiligo on genital self-image, sexual function, and quality of life in female patients. This cross-sectional study included 50 sexually active women with vitiligo and 25 women without vitiligo. All participants subjected to full history taking and examination. Extent of vitiligo was assessed with the Vitiligo Area Scoring Index score, sexual function with the Female Sexual Function Index, genital self-image with Female Genital Self-Image Score and quality of life with the Dermatology Life Quality Index questionnaires. The main outcome measures were correlation between Vitiligo Area Scoring Index, Female Genital Self-Image Score, Female Sexual Function Index, and Dermatology Life Quality Index domains was determined using t test and Pearson correlation. This study revealed a negative correlation between the Vitiligo Area Scoring Index score and sexual satisfaction. Vitiligo Area Scoring Index and Dermatology Life Quality Index score was significantly correlated with Arabic Version of the Female Genital Self-Image Score alone and with Arabic Version of the Female Sexual Functioning Index alone and with both the Arabic Version of the Female Genital Self-Image Score and the Arabic Version of the Female Sexual Functioning Index (p <.05). Sexual and psychological assessment of patients with vitiligo is imperative to improve outcomes and increase patients' compliance with treatment. PMID:25650731

  6. Inhibited Sexual Desire and Sexual Avoidance

    OpenAIRE

    Morse, William I.

    1985-01-01

    Inhibited sexual desire (ISD) is one of the most common sexual dysfunctions, especially in women. Family physicians have an opportunity to recognize ISD before the associated problems become entrenched, and to guide couples toward satisfactory resolution. A summary is presented of current thinking on ISD and its causes. Case reports and observations about frequency of and treatment for ISD are included. Much less has been written about sexual avoidance in the presence of desire. A definition ...

  7. 性功能障碍患者心理状况调查分析及护理干预%Investigation and Analysis of Psychological Status of Patients with Sexual Dysfunction and Nursing Intervention

    Institute of Scientific and Technical Information of China (English)

    夏旭

    2014-01-01

    Objective:Through the investigation of the psychological status of patients with sexual dysfunction,used effective nursing intervention measures,in order to better serve the patients.Method:Symptom checklist 90(SCL-90) and the statistical method were used to analyse the patients psychological status investigation, and formulate relevant nursing measures.Result:There were statistical significance differences in force,sexual dysfunction in patients with somatization,anxiety, psychoticism factor score and the number of positive items compared with the norm(P<0.05),psychological and social problems of sexual dysfunction patients often accompanied by more.Conclusion:Through the analysis of sexual dysfunction in patients with psychological,coupled with effective nursing intervention,can inspire and mobilize the enthusiasm of patients,reduce the psychological burden of patients and the pressure,to enhance the confidence of the patients, the family affection, staff care about inter early rehabilitation.%目的:通过调查分析性功能障碍患者的心理状况,有效应用护理措施干预,以期更好服务于患者。方法:应用症状自评量表(SCL-90)和统计学方法对患者心理状况调查分析,制定相关护理措施。结果:性功能障碍患者强迫、躯体化、焦虑、精神病性因子分及阳性项目数与常模比较显著高,差异有统计学意义(P<0.05),性功能障碍患者常常伴有较多的心理社会问题。结论:通过对性功能障碍患者的心理分析,加上有效地护理干预,可以启发和调动患者的积极性,减轻患者的心理负担和压力,增强患者的治疗信心,使其在家人的亲情中、医护人员的关心间早日康复。

  8. 性自慰行为与静脉性勃起功能障碍的相关性分析%Correlation between sexual masturbation behavior and venous erectile dysfunction

    Institute of Scientific and Technical Information of China (English)

    刘勇刚; 孙毅海; 陶卫琦; 刘昕; 黄才胜; 黄超斌

    2014-01-01

    目的:探讨性自慰行为与静脉性勃起功能障碍的相关性。方法对173例确诊为静脉性勃起功能障碍患者的性自慰行为资料进行logistic回归分析,以初次性自慰年龄、频率、性自慰病程、性自慰时是否伴有阴茎不适症状,以及性自慰时期是否有性伴侣等5项因素为变量指标。结果性自慰频率、性自慰病程和性自慰时是否伴有阴茎不适症状与静脉性勃起功能障碍依次相关,P值分别为0.0069、0.0108、0.0195,标准化回归系数分别为0.4925、0.3687、0.2943;而性自慰时期是否有性伴侣和初次性自慰年龄与静脉性勃起功能障碍无显著相关性(P>0.05)。结论性自慰频率、性自慰病程以及是否伴有阴茎不适症状与静脉性勃起功能障碍的发生有密切关系。%Objective To study the correlation between sexual masturbation behavior and venous erectile dysfunction. Methods The clinical data of sexual masturbation behavior in 173 patients with venous erectile dysfunction were recorded and statistically analyzed with logistic regression model. Age of the first time masturbation, frequency, duration, penis symptoms, and sex partner were taken as variables. Results Venous erectile dysfunction was significantly related to the frequency, duration, penis symptoms. The P values were 0.0069,0.0108 and0.0195 The standard regression coefficients were 0.4925, 0.3687, and 0.2943 respectively. Sex partner and age of the first time masturbation were not associated with the venous erectile dysfunction (P>0.05). Conclusion Venous erectile dysfunction is corrected with the frequency, duration, penis symptoms in sexual masturbation behavior.

  9. Comparison of the Effects of Elaeagnus angustifolia Flower Capsule and Sildenafil Citrate Tablet on Anxiety Resulting From Sexual Dysfunction in Women Referring to the Selected Clinics of Shiraz University of Medical Sciences.

    Science.gov (United States)

    Zeinalzadeh, Sanaz; Akbarzadeh, Marzieh; Mohagheghzadeh, Abdolali; Faridi, Pouya; Sayadi, Mehrab

    2016-07-01

    Dissatisfaction from sexual relationships can result in deprivation as well as problems, such as depression, anxiety, and destruction of family's mental health. One hundred twenty-five women (18 to 40 years) who suffered from hypoactive sexual desire disorder were divided into Elaeagnus angustifolia flower (4.5 g g daily for 35 days), sildenafil citrate tablet (50 mg for 4 weeks), and control groups. The study data were collected using the Female Sexual Function Index and Spielberger's questionnaire and measurement of thyroid-stimulating hormone and prolactin hormone. In the Elaeagnus angustifolia group, the mean score of state and trait anxiety decreased after the intervention. In the sildenafil citrate group also, the mean score of state anxiety decreased from 22.15 ± 4.98 to 20.1 ± 5.15 (P = .001) and that of trait anxiety decreased from 23.07 ± 4.44 to 21.55 ± 4.82 (P = .002) after the intervention. Consumption of sildenafil citrate tablet was effective in reduction of the mean score of anxiety resulting from sexual dysfunction. PMID:26224722

  10. The Sexual Functioning of Adult Women Molested as Children: A Review of Empirical Studies.

    Science.gov (United States)

    Clarke, Julie Lynn

    This paper reviews the research literature from 1978 to 1991 that addresses long-term effects of childhood sexual abuse on adult women's sexual functioning. Frequently reported long-term effects of childhood sexual abuse are noted, including both sexual dissatisfaction and sexual dysfunction. In terms of sexual dysfunction, it is noted that adult…

  11. Orgasmic dysfunction

    Science.gov (United States)

    ... of a satisfying, intimate experience for both partners. Sexual desire will often decline, and sex occurs less often. ... sexual stimulation and response Learning to clearly communicate sexual needs and desires, verbally or non-verbally How to make sex ...

  12. Sexuality and chronic illness.

    Science.gov (United States)

    Steinke, Elaine E

    2013-11-01

    Sexual function is often affected in individuals living with chronic illness and their partners, and multiple comorbidities increase the likelihood of sexual dysfunction. This review focuses on the areas of cardiovascular disease, respiratory conditions, and cancer, all areas for which there are practical, evidence-based strategies to guide sexual counseling. Although nurses have been reluctant to address the topic of sexuality in practice, a growing number of studies suggest that patients want nurses to address their concerns and provide resources to them. Thus, nurses must be proactive in initiating conversations on sexual issues to fill this gap in practice. PMID:24066783

  13. Sexuality of dissocial persons

    Directory of Open Access Journals (Sweden)

    Marta Janus

    2016-02-01

    Full Text Available Introduction. The development of personality disorders as well as sexual disorders is defined by the common time spectrum as well as deficits and changes in such areas as biological, environmental and mental area. Dissocial (antisocial personality disorder is characterised by a pervasive pattern of disregard for, or violation of, the rights of others. The indices of the discussed disorder can be found in specific patterns of social inadequacy occurring during childhood and puberty. At the same time, characteristic indices of social functioning at a young age often indicate subsequent dysfunctions in the area of sexuality. Aim. The aim of this paper is to explain sexual functioning of persons with dissocial personality disorder (including the relation with sexual dysfunctions, and to ascertain issues that need further empirical studies. Method. As a result of analysis of available literature (matched with EBSCO database search fulfilling criteria of sample size, accuracy of examination procedure, conclusions and discussion 5 articles fulfilling criteria cited above has been found. Conclusions: Based on literature overview, it appeared to be impossible to determine one coherent way of sexual functioning of dissocial persons, and to establish causal relationship of sexual dysfunctions and dissocial personality disorder. However, it is possible to indicate group of most characteristic dysfunctional sexual behaviours. Noteworthy, available publication analyse only selected aspects of sexual behaviours in small, homogenous groups. There is a lack of review studies as well as multi-faceted studies.

  14. Hidden Risks of Erectile Dysfunction "Treatments" Sold Online

    Science.gov (United States)

    ... mail Consumer Updates RSS Feed Hidden Risks of Erectile Dysfunction "Treatments" Sold Online Printer-friendly PDF (297 KB) ... Men looking online for "dietary supplements" to treat erectile dysfunction (ED) or enhance their sexual performance should beware: ...

  15. Effects of Kegel exercise on postpartum female sexual dysfunction%凯格尔训练治疗产后女性性功能障碍的效果观察

    Institute of Scientific and Technical Information of China (English)

    冯小丽; 李先锋; 吴瑾

    2012-01-01

    Objective To investigate the effects of Kegel exercise in the treatment of postpartum female sexual dysfunction. Methods A total of 134 women undergoing childbirth from Oct 2008 to Oct 2010, aged 21-24 years old, were diagnosed as postpartum female sexual dysfunction (PPFSD) according to the scale of PPFSD and underwent full treatment course of Kegel exercise. The women were randomly divided into the rehabilitation group (n= 68) and the con-trol group (n=66). The rehabilitation group were treated with Kegel exercise under the guidance of a doctor, 5~30 min, 2-3 times/day,for 8 weeks. While the control group had conventional health education. After treatment, the intensity of pelvic floor muscle contraction, frequency of sexual intercourse, and incidence of sexual intercourse pain were evaluat-ed and compared between the two groups. Results The rehabilitation group showed significantly better outcomes re-garding the intensity of pelvic floor muscle contraction, frequency of sexual intercourse, and incidence of sexual inter-course pain (P0.05). Conclusion Kegel exercise is a simple but effective treatment for postpartum female sexual dysfunction, which is worthy for application in primary hospitals.%目的 探讨凯格尔训练方法治疗产后女性性功能障碍的疗效.方法 选取珠海市第二人民医院2008年10月至2010年10月分娩的产妇中,通过《产后女性性功能障碍诊断量化表及评分表》自制的问卷调查表确诊为产后女性性功能障碍并坚持治疗至疗程结束134例患者(年龄21~42岁)为研究对象,将其随机分为康复组(n=68)及对照组(n=66).康复组在医生指导下进行一对一的性健康教育及凯格尔训练指导,2~3次/d,每次练习15~30 min,持续8周以上.对照组实施常规的健康教育.疗程结束后分别对两组患者的盆底肌收缩力、性生活频度、及性交痛发生率等方面进行评估.结果 康复组在盆底肌收缩力、性生活频度、性生活

  16. [Physiology and physiopathology of sexuality].

    Science.gov (United States)

    Cuzin, Béatrice

    2016-01-01

    From desire to orgasm, sexuality, in women and men, is underpinned by a complex organic, psychological and emotional function. Sexual dysfunction encompasses diverse aetiologies, including chronic diseases and iatrogenesis resulting from medication or surgery. The effects of a chronic disease can have an impact on all phases of the sexual response. PMID:27317816

  17. Aging and sexuality.

    OpenAIRE

    Holzapfel, S.

    1994-01-01

    Recent research suggesting that a high proportion of men and women remain sexually active well into later life refutes the prevailing myth that aging and sexual dysfunction are inexorably linked. Age-related physiological changes do not render a meaningful sexual relationship impossible or even necessarily difficult. In men, greater physical stimulation is required to attain and maintain erections, and orgasms are less intense. In women, menopause terminates fertility and produces changes ste...

  18. Clinical study of kuntai capsule on female sexual dysfunction with type II diabetes%坤泰胶囊治疗女性 II 型糖尿病患者性功能障碍的临床研究

    Institute of Scientific and Technical Information of China (English)

    李志杰; 韩世愈; 史焱; 朱宏

    2014-01-01

    目的:探讨坤泰胶囊对女性II型糖尿病患者性功能障碍(FSD)的治疗效果。方法:选取44例FSD患者,随机分为对照组和观察组,各22例。观察组给予坤泰胶囊口服治疗,对照组给予西地那非治疗,比较两组患者治疗前后睾酮(T)和雌激素(E2)的水平,并用女性性功能量表(FSFI)测量两组患者治疗前后的性功能变化。结果:观察组治疗后的T和E2水平较治疗前明显升高(P<0.05),对照组治疗前后无明显变化(P>0.05);观察组较治疗前性功能障碍得到了改善,在性欲、性唤起、性高潮、满意度维度以及总体满意度均明显优于治疗前与对照组(P<0.05),对照组仅在阴道润滑度及疼痛维度较治疗前有所改善(P<0.05)。结论:坤泰胶囊能有效地改善女性II型糖尿病患者性功能障碍,其机制可能与提高T水平以及E2水平有关。%Objectives:To evaluate the clinical effects of Kuntai capsule for female sexual dysfunction with type II diabetes (FSD).Methods:44 patients with FSD were randomly divided into control group and observation group,with 22 cases in each group.The patients in observation group were given Kuntai capsule orally,while pa-tients in the control group were given Sildenafil citrate.The levels of testosterone (T)and estradiol (E2)were com-pared before and after treatment in both groups,and sexual function were measured using the female sexual function index (FSFI).Results:The levels of T and E2 in observation group after treatment were significantly elevated com-pared with those before treatment (P0.05 );sexual dysfunction of patients in the observation group was been improved than those before treatment and in control group,which inclued sexual desire,arousal,orgasm,satisfaction and overall satisfaction (P<0.05 ),vagi-nal lubrication and pain dimension were been improved in the control group only than before treatment(P<0

  19. Diagnostic evaluation of erectile dysfunction.

    Science.gov (United States)

    Miller, T A

    2000-01-01

    Erectile dysfunction, the persistent inability to attain or maintain penile erection sufficient for sexual intercourse, affects millions of men to various degrees. The majority of cases have an organic etiology, most commonly vascular disease that decreases blood flow into the penis. Regardless of the primary cause, erectile dysfunction can have a negative impact on self-esteem, quality of life and interpersonal relationships. The initial step in evaluation is a detailed medical and social history, including a review of medication use. Discussion with the patient's sexual partner may clarify exacerbating issues. The physical examination focuses on the cardiovascular, neurologic and urogenital systems. Laboratory tests are useful to screen for common etiologic factors and, when indicated, to identify hypogonadal syndromes. Appropriate evaluation of erectile dysfunction leads to accurate advice, management and referral of patients with erectile dysfunction. PMID:10643952

  20. Sexual function and obesity

    DEFF Research Database (Denmark)

    Larsen, S H; Wagner, G; Heitmann, B L

    2007-01-01

    OBJECTIVE: To review the literature on the relationship between obesity and sexual function. METHOD: A search in the medical literature from 1966 and onwards was carried out through Medline and Embase for publications on obesity, in combination with Medical Subject Heading words related to sexual...... function and dysfunction. COMMENTS: Four prospective and seven cross-sectional studies were found describing association between obesity and erectile dysfunction (ED). One cross-sectional study was found describing obesity and female sexual dysfunction (FSD). The prospective studies on ED all demonstrated...... sexual activity among both men and women after weight loss intervention. CONCLUSION: Support for the assumption that obesity is associated with ED was found in both prospective and cross-sectional studies. FSD was not adequately described in the literature and prospective studies are needed here. Results...

  1. Sexual dysfunction, depression, and anxiety in young women according to relationship status: an online survey Disfunção sexual, depressão e ansiedade em mulheres jovens de acordo com o status de relacionamento: uma pesquisa on-line

    Directory of Open Access Journals (Sweden)

    Valeska Martinho Pereira

    2013-01-01

    Full Text Available BACKGROUND: Sexual dysfunction is a common, still poorly understood problem among women. Being or not in a relationship seems to be a risk factor for sexual dysfunction. OBJECTIVES: To evaluate the presence of sexual problems, anxiety, and depression in young women and to correlate findings with current relationship status (single, in a committed relationship, or married. METHODS: Data were collected trough an online survey from a total of 155 women aged between 20 and 29 years. Sociodemographic data were collected, and both the Hospital Anxiety and Depression scale and the Female Sexual Function Index were applied. Data were statistically analyzed using the chi-square and Kruskal-Wallis tests, and groups were compared in 2 x 2 matrices using the Mann-Whitney test. RESULTS: Single women showed a significantly higher prevalence of problems in the lubrication (45.3%, orgasm (53.1%, satisfaction (67.2%, and pain (50% domains and also in total Female Sexual Function Index scores (60.9% in comparison with the other groups. Additionally, significantly higher depression scores were found among single women (5.89±3.3 in comparison to those in a committed relationship (4.05±2.83. Anxiety scores were similar in all groups. CONCLUSION: Our findings suggest that single women have a poorer sexual function and are more likely to have mood disorders in comparison to their peers involved in stable relationships.CONTEXTO: Disfunção sexual é um problema comum e ainda pouco compreendido entre mulheres. Estar ou não em um relacionamento parece ser um fator de risco para disfunção sexual. OBJETIVO: Avaliar a presença de problemas sexuais, ansiedade e depressão em jovens mulheres e correlacionar os achados ao estado de relacionamento atual (solteiras, em relacionamento sério ou casadas. MÉTODOS: Dados foram coletados através de pesquisa on-line de um total de 155 mulheres com idade entre 20 e 29 anos. Foram coletados dados sociodemográficos, e a Escala

  2. Sexual function in female patients with obstructive sleep apnea

    DEFF Research Database (Denmark)

    Giraldi, Annamaria G.E.; Petersen, Marian; Kristensen, Ellids;

    2011-01-01

    . Female Sexual Function Index, Female Sexual Distress Scale and four questions from Life Satisfaction-11 (Lisat-11). Results. Female Sexual Function Index indicated that obstructive sleep apnea patients were at a higher risk for having sexual difficulties. Female Sexual Distress Scale showed significantly...... more sexual distress in the obstructive sleep apnea group. Manifest Female Sexual Dysfunction (combined data from Female Sexual Function Index and Female Sexual Distress Scale) showed that female patients with obstructive sleep apnea also had more sexual dysfunction. Severity of sleep apnea was...... function and distress are sparse. Aim. To investigate sexual dysfunction and sexual distress in female patients with obstructive sleep apnea and to determine which factors are of importance for their sexual function. Methods. We investigated 80 female patients (ages 28–64) admitted to a sleep laboratory...

  3. Flibanserin for Treating Hypoactive Sexual Desire Disorder

    OpenAIRE

    Sang, Jae Hong; Kim, Tae-Hee; Kim, Soo Ah

    2016-01-01

    There have been several products developed for male sexual dysfunction. However, developing agents for female sexual dysfunction is lagging behind for various reasons. Sildenafil citrate (Viagra) and Tadalafil (Cialis), which have been prescribed for male sexual function disorders, are known to act on vessels.[1] On the other hand, flibanserin is thought to act on brain. Flibanserin has been approved by U. S. Food and Drug Administration (FDA) for treatment of hypoactive sexual desire disorde...

  4. Analysis of sexual dysfunction after Mile’s operation in young male patients%青年男性直肠癌患者 Mile’s 术后性功能变化分析

    Institute of Scientific and Technical Information of China (English)

    荣桂芳; 陈智彬

    2015-01-01

    Objectives:To analyze the sexual function in young male patients with rectal carcinoma after Mile’s surgery,in order to improve the sexual function.Methods:Questionnaires were administered to the 86 young male patients after rectal Mile’s surgery at the 3 rd month and 6 th month respectively,including the Self -Rat-ing Anxiety Scale (SAS)and the International Index of Erectile Function questionnaire (IIEF)to understand the risk factors for their sexual dysfunction.All the questions were designed to understand the factors of sexual dysfunc-tion and the relationships among them.Results:A total of 82 valid questionnaires were collected.All the 82 young male patients had varying degrees of anxiety in the two surveys.According to the SAS score,there were 26 (31 .71 %)cases reporting mild anxiety in the first survey versus 42 (51 .22%)cases in second survey,38 (46.34%)cases showing moderate anxiety versus 21 (25.61 %),and 1 8 (21 .95%)cases indicating severe anxi-ety versus 9 (1 0.97%)respectively.All patients had sexual desire disorder and decreased sexual satisfaction:34 (53.96%)cases in the first survey showed erectile dysfunction versus 26 (41 .27%)in the second survey;1 8 (28.57%)cases had insertion obstacle vs.23 (36.51 %)cases in the second survey;and 38 (60.32%)cases suffered from sexual desire decreased vs.1 6 (25.4%)cases in the second survey.The sexual dysfunction presen-ted better postoperative at the 6 th month than 3 rd month (χ2 =1 0.1 1 ,P <0.05),and the SAS evaluation was nega-tively correlated with sexual dysfunction both at postoperative 6 th month and 3 rd month (r =1 .052 and r =1 .1 7,P <0.05).The incidence of ED in the second survey decreased compared with the first survey,with statically signifi-cant difference (χ2 =1 0.1 1 ,P <0.05).Conclusions:Operation injury and postoperative psychological obstacles (such as anxiety,depression,and social intercourse disorders)are main factors leading to sexual dysfunction.It is of clinical significance

  5. Scripted Sexual Health Informational Intervention in Improving Sexual Function in Patients With Gynecologic Cancer

    Science.gov (United States)

    2016-05-10

    Anxiety Disorder; Cervical Cancer; Endometrial Cancer; Female Reproductive Cancer; Gestational Trophoblastic Tumor; Ovarian Epithelial Cancer; Ovarian Germ Cell Tumor; Sexual Dysfunction; Uterine Sarcoma; Vaginal Cancer; Vulvar Cancer

  6. 南京城区宫颈疾病女性性功能障碍调查研究%Investigation of Female Sexual Dysfunction in Patients of Cervical Disease in Nanjing City

    Institute of Scientific and Technical Information of China (English)

    雷雨; 阚延静; 潘连军

    2013-01-01

    Objective: To investigate the incidence and risk factors of female sexual dysfunction (FSD) in patients of cervical disease. Methods: A retrospective survey on women aged 18-55 years old with normal coitus in the cervical out-patients of Maternity and Child Health Hospital Affiliated to Nanjing Medical University was conducted. Different HPV genotypes were detected in cervical exfoliated cells by the method of PCR and membrane of the hybrid. Any type of HPV which had been detected can be seen as HPV positive. The cervical specialists through conventional gynecologial examination learned women who suffered from cervical disease. Female sexual function index (FSFI) questionnaire was applied to assess sex condition in nearly a month. Multiple Logistic regression analysis was used to analyze independent risk factors. Results: In the 2 045 copies of the questionnaires, 472 cases were refused, and 458 cases were removed. Totally, 1 573 subjects completed the questionnaires and 1115 (71%) valid questionnaires that met the ctiteria were finally included for analysis. There were 486 (43.6%) women with cervical disease in 1 115 patients. There were 254 (52.3%) cases who have sexual dyfunction in patients with cervical disease. The results had a significant difference between cervical disease group and normal group. The score of patients reduced in sexual desire, sexual arousal, vaginal lubrication, orgasm, sexual satisfaction and sexual pain (P cervical hypertrophy > cervical erosion > cervical polyp. Conclusion: In Nanjing city, the FSD incidence is high in out-patients of cervical disease. It is necessary to strengthen promotion of sexual health, implement regular physical examination of reproductive system and form a good sexual life to reduce the FSD incidence.%目的:了解宫颈疾病女性性功能障碍(female sexual dysfunction,FSD)患病率及危险因素.方法:采用回顾性调查方法,对在南京医科大学附属南京妇幼保

  7. Diagnosis and treatment of male sexual dysfunction caused by hyperprolactinemia%血高催乳素血症导致男性性功能障碍的诊治分析

    Institute of Scientific and Technical Information of China (English)

    杨雪峰; 杨土生; 郭善媚

    2014-01-01

    目的:分析血高催乳素血症导致的男性性功能障碍的诊断与治疗策略。方法:回顾性分析我院男科2011年至2012年收治的32名血高催乳素血症导致的男性性功能障碍患者的诊疗资料,总结血高催乳素血症导致男性性功能障碍的诊断与治疗方法。所有数据均建立Excel 2013数据库,并采取SPSS19.0的统计学软件进行数据分析,计量资料均采取t检验,分析治疗前后患者血清性激素的变化。结果:32例患者中有特发性高催乳素血症23例(71.88%)、有垂体腺瘤4例(12.50%)、有微腺瘤5例(15.63%)。有勃起功能障碍29例(90.63%)、有性欲减退32例(100.00%)、有性高潮障碍7例(21.88%)。32例患者治疗后的血清催乳素含量明显低于治疗前,差异具有统计学意义(P<0.01)。32例患者治疗后的黄体生成素、卵泡刺激素以及睾酮水平均要明显高于治疗前,差异具有统计学意义(P<0.01)。经治疗后32例患者的勃起功能障碍、性欲减退以及高潮障碍等症状均有所改善。结论:高催乳素血症导致的男性性功能障碍经过病史采集、临床特征、勃起功能指数测定、体格检查、激素测定以及垂体的影像学检查可明确诊断,甲磺酸溴隐亭与十一酸睾酮的治疗效果较好,值得临床推广。%Objectives:To analyze the diagnostic and therapeutic strategies of male sexual dysfunction caused by hyperprolactinemia.Methods:A retrospective analysis of the data of 32 male subjects with sexual dys-function caused by hyperprolactinemia treated in our hospital from 201 1 to 2012 was conducted to summarize the di-agnostic and therapeutic methods of male sexual dysfunction caused by hyperprolactinemia.All data were put into Excell2013 database and statistical software SPSS19.0 was used for data analysis;measurement data were taken t test to analyze the changes of serum sex hormones before

  8. Proposed therapeutic proceedings for erectile dysfunction. Cognitive-behavioral approach.

    Directory of Open Access Journals (Sweden)

    Oettingen, Justyna

    2014-06-01

    Full Text Available Current treatment methods of sexual problems are short-term and problem-oriented, therefore it is recommended to treat sexual dysfunctions with cognitive-behavioral approach (CBT. This paper is a compilation of available therapeutic methods, which were here integrated by the author into a ready-to-use erectile dysfunction therapeutic protocol.

  9. Studies on sexual function of patients with erectile dysfunction-no sexual life using self-estimation index of erectile function-no sexual life%阴茎勃起功能自我评价表对中青年无性生活勃起功能障碍患者的多维评估

    Institute of Scientific and Technical Information of China (English)

    张志超; 袁亦铭; 高冰; 彭靖; 宋卫东; 辛钟成; 金杰; 郭应禄

    2011-01-01

    Objective To estabalish a new conception, Erectile Dysfunction-no sexual life (ED-NS), so as create an evaluating questionnaire, Self-estimation Index of erectile function-No sexual life (SIEF-NS) so as to investigate its clinical reliability. Methods The conception of ED-NS was identified and the SIEF-NS questionnaire was established. Patients who complained of ED-NS and normal controls were enrolled into the research and assessed the erectile function was assessed with SIEF-NS.The SIEF-NS includes 12 questions, such as sexual libido, general erectile function, nocturnal penile erection, erectile function during foreplay, erectile function during audio-video sexual stimulation,confidence, depression, etc and each question has 5 point scales. Results Sixty-one ED-NS patients and 57 controls were enrolled into the study and assessed erectile function with SIEF-NS. The mean score of each question and integral score of SIEF-NS in ED-NS patients were significantly different from normal controls (P<0. 05). When the integral score was 35 points according to the ROC curve of integral score, the sensitivity of SIEF-NS was 88.5% and specificity was 96. 5%. Conclusions ED-NS is a new conception to define patients who have erectile dysfunction without sexual life. SIEFNS is suggested to be a useful method for the evaluation of ED-NS patients.%目的 确立无性生活勃起功能障碍(ED-NS)的定义,制定ED-NS问卷调查表评估勃起功能状态,并判断其效果.方法确立ED-NS定义,并设计制定勃起功能自我评价表(SIEFNS).收集符合ED-NS定义患者和正常对照病例作为研究对象,并分为ED-NS和正常对照2组.ED-NS患者61例,年龄18~38(26.2±4.3)岁;正常对照组57例,年龄18~33(24.9±4.1)岁.分别填写SIEF-NS问卷.问卷共有12个问题,涉及性欲、总体勃起情况、夜间和晨起勃起情况、异性相处条件下勃起情况和视听觉性刺激下勃起情况5个方面,每个问题分为5分,收集各项问题评

  10. Psychosocial aspects of ejaculatory dysfunction and male reproduction.

    Science.gov (United States)

    Wincze, John P

    2015-11-01

    This article provides a summary of the biopsychosocial model and the assessment and treatment of male sexual dysfunction as manifested in cases of infertility. In couples trying to get pregnant, a unique set of psychosocial and behavioral changes may evolve that directly interferes with a couple's usual pattern of sexual behavior, resulting in sexual dysfunction. The unique set of changes is discussed and how these changes impact on erectile and ejaculatory function. Strategies for assessing and managing male sexual dysfunction that compromise fertility are reviewed. PMID:26297900

  11. Healthy Sexuality

    Medline Plus

    Full Text Available ... Healthy Sexuality Sexuality is the experience and/or expression of a person as a sexual being. Sexuality ... and explanations. Sexuality is the experience and/or expression of a person as a sexual being. It ...

  12. Sexual abuse evaluation in urological practice

    OpenAIRE

    Beck, Jacobus Johannes Hendrikus

    2013-01-01

    The primary aim of this study is to investigate the prevalence of sexual abuse in a urological outpatient clinic. Can differences been made in urological population, i.e. general urological clinic, a university urological clinic and a tertiary university pelvic floor clinic? Do urologists inquire about female sexual dysfunction and sexual abuse history? And if so, what percentage of the Dutch urologist does so? What do sexual abuse patients think about screening for sexual abuse history? Can ...

  13. Spina bifida and sexuality

    DEFF Research Database (Denmark)

    von Linstow, Michael Ernst; Biering-Sørensen, Ida; Liebach, Annette;

    2014-01-01

    OBJECTIVE: To evaluate sexual function amongst adult individuals with spina bifida and to register their subjective satisfaction with their sexual life and relationships. SETTING: Department for Spinal Cord Injuries, East Denmark. STUDY DESIGN AND METHODS: Cohort study. Medical record information......, neurological examination, personal interview, Functional Independence Measure (FIMTM), Medical Outcome Study Short Form 36 (SF-36) on quality of life, and questions on sexual function and related topics. Study cohort: Fifty-three participants (27 women, 26 men) with spina bifida (mean age 27.1, range 18......-35) years. Response rate 74%. RESULTS: Fifty-one percent of subjects regarded their sexual life as a failure or dysfunctional. However, 45% reported being satisfied with their sexual life. Participants with partners were more satisfied with their sexual life than those without partners. Faecal, but not...

  14. Sexuality research in India: An update.

    Science.gov (United States)

    Prakash, Om; Rao, T S Sathyanarayana

    2010-01-01

    This review provides the available evidence on sexual dysfunctions in India. Most of the studies have concentrated on male sexual dysfunction and hardly a few have voiced the sexual problems in females. Erectile dysfunction (ED), premature ejaculation (PME) and combinations of ED and PME appear to be main dysfunctions reported in males. Dhat syndrome remains an important diagnosis reported in studies from North India. There is a paucity of literature on management issues with an emergent need to conduct systematic studies in this neglected area so that the concerns of these patients can be properly dealt with. PMID:21836690

  15. Sexual Harassment and Sexual Bulllying

    Science.gov (United States)

    ... a Friend Who Cuts? Sexual Harassment and Sexual Bullying KidsHealth > For Teens > Sexual Harassment and Sexual Bullying ... being sexually harassed or bullied. What Are Sexual Bullying and Harassment? Just like other kinds of bullying, ...

  16. 盆底生物反馈电刺激联合盆底肌肉锻炼治疗性功能障碍30例临床分析%The clinical analysis of treatment of 30 cases with sexual dysfunction with biofeedback pelvic floor electrical stimulation and pelvic floor muscle exercise

    Institute of Scientific and Technical Information of China (English)

    周玉萍; 高霞; 岳艳; 张毅

    2012-01-01

    目的:观察盆底生物反馈电刺激联合盆底肌肉锻炼治疗性功能障碍的效果.方法:选择产后及围绝经期性功能障碍患者各30例,将其随机分为研究组(采用PHEIX神经肌肉治疗仪联合盆底肌肉锻炼)30例与对照组(采用传统的心理治疗结合药物治疗)30例,通过调查,评估盆底肌康复治疗女性性功能障碍的效果.结果:研究组的盆底肌收缩时间、阴道内压力、性生活满意程度、性感程度自我评价、他人评价、性生活质量处于高水平等指标均明显优于对照组(P<0.01).结论:盆底生物反馈电刺激联合盆底肌肉锻炼治疗性功能障碍是一种经济、实用、有效、合理的方法.%Objective: To evaluate the effects of the biofeedback pelvic floor electrical stimulation and pelvic floor muscle exercise on sexual dysfunction. Methods: Thirty postpartum and menopause cases with sexual dysfunction were andomly divided into the study group (treatment with PHEIX neuromuscular instrument) and pelvic floor muscle exercise and the control group(traetment with traditional psychotherapy and drug). The effects of pelvic floor muscle exercise on sexual dysfunction were evaluted using the " female sexual dysfunction diagnostic scale and the scoring sheet" survey. Results:The contraction time of pelvic floor muscle,the pressure within the vagina, sexual satisfaction, the sexy degree of self-evaluation, other evaluations and the quality of sexual life of the study group were better than these of the control group ( P < 0. 01 ). Conclusions:Treatment of sexual dysfunction with the biofeedback pelvic floor electrical stimulation and pelvic floor muscle exercise is an economical, practical, effective and reasonable approach.

  17. Neurally augmented sexual function.

    Science.gov (United States)

    Meloy, S

    2007-01-01

    Neurally Augmented Sexual Function (NASF) is a technique utilizing epidural electrodes to restore and improve sexual function. Orgasmic dysfunction is common in adult women, affecting roughly one quarter of populations studied. Many male patients suffering from erectile dysfunction are not candidates for phosphdiesterase therapy due to concomitant nitrate therapy. Positioning the electrodes at roughly the level of the cauda equina allows for stimulation of somatic efferents and afferents as well as modifying sympathetic and parasympathetic activity. Our series of women treated by NASF is described. Our experience shows that the evaluation of potential candidates for both correctable causes and psychological screening are important considerations. PMID:17691397

  18. Management of ejaculatory dysfunction.

    Science.gov (United States)

    McMahon, C G

    2014-02-01

    Ejaculatory dysfunction is a common complaint and is often associated with a reduced quality of life for sufferer and partner. The spectrum of ejaculatory dysfunction extends from premature ejaculation (PE) to delayed ejaculation (DE) and anejaculation. Over the past 20-30 years, the PE treatment paradigm, previously limited to behavioural psychotherapy, has expanded to include drug treatment. Multiple well-controlled, evidence-based studies have demonstrated the efficacy and safety of selective serotonin re-uptake inhibitors in delaying ejaculation, confirming their role as first-line agents for the treatment of lifelong and acquired PE. More recently, there has been increased attention to the psychosocial consequences of PE, its epidemiology, its aetiology and its pathophysiology by both clinicians and the pharmaceutical industry. DE and anejaculation are probably the least common, least studied and least understood of the male sexual dysfunctions. However, their impact is significant as they may result in a lack of sexual fulfilment for both the man and his partner, an effect further compounded when procreation is among the couple's goals of sexual intercourse. The causes of DE, anejaculation and anorgasmia are manifold. Numerous psychotherapeutic treatments are described for the management of delayed or anejaculation. Although some appear to be effective, none has been properly evaluated in large-scale samples. Treatment of DE or anejaculation with pharmacotherapy has met with limited success. No drugs have been approved by regulatory agencies for this purpose, and most drugs that have been identified for potential use have limited efficacy, impart significant side-effects or are yet considered experimental in nature. PMID:24528812

  19. Psychogenic erectile dysfunction. Classification and management.

    Science.gov (United States)

    Rosen, R C

    2001-05-01

    Psychogenic factors are involved alone or in combination with organic causes in a substantial number of cases of erectile dysfunction. Epidemiologic studies have implicated the role of depressed mood, loss of self-esteem, and other psychosocial stresses in the cause of erectile dysfunction. A new definition and classification of psychogenic erectile dysfunction has been proposed based on recent clinical and research findings. According to this new classification, psychogenic erectile dysfunction is categorized as generalized or situational type, with subcategories of each type proposed. Traditional treatment approaches for psychogenic erectile dysfunction have included anxiety reduction and desensitization procedures, cognitive-behavioral interventions, guided sexual stimulation techniques, and couples' or relationship counseling. Recently, these approaches increasingly have been combined with pharmacologic therapy such as sildenafil. Special situations have been identified in which combining psychosocial interventions with medical therapy is recommended. These situations include problems of sexual initiation, low sexual desire, other sexual dysfunctions, and significant couples' or relationship problems. More research is needed on the role of psychosocial interventions in the treatment of erectile dysfunction. PMID:11402580

  20. [Erectile and Ejaculatory Dysfunction].

    Science.gov (United States)

    Gross, Oliver; Sulser, Tullio; Eberli, Daniel

    2015-11-25

    The inability to achieve an erection of the penis sufficient for sexual activity is called erectile dysfunction (ED). In most cases, the diagnosis can be made by medical history. The prevalence of ED in men at the age of 65 has been reported to be up to 50%. Premature ejaculation has a prevalence, up to 20% and is the most frequent ejaculatory dysfunction. The etiology of ED can involve psychological, vascular, neurogenic, hormonal or urogenital pathologies. The main pathophysiological mechanisms of ED are vascular disorders such as diabetes mellitus and atherosclerosis. Because of the common pathophysiology, patients diagnosed with ED should have a diagnostic work-up for systemic vascular pathologies to prevent concomitant cardiac events. Treatment options include invasive and non-invasive procedures. PMID:26602851

  1. Postradiation sexual pathology

    International Nuclear Information System (INIS)

    In the monograph literature data and results of authors' own studies on low radiation dose influence on sexual function of Chernobyl accident liquidators are generalized. Results of sexual, endocrine and hormonal examination are given. Particular attention is paid to diagnosis, pathogenesis and treatment of postradiation sexologic dysfunctions. The work is intended for sex-pathologists, radiation endocrinologists, as well as for doctors servicing of sufferers from radiation action. (author)

  2. "Viagra stories": challenging 'erectile dysfunction'.

    Science.gov (United States)

    Potts, Annie; Grace, Victoria; Gavey, Nicola; Vares, Tiina

    2004-08-01

    Medical approaches to sexual difficulties prioritise the physical aspects of sexuality over other aspects, locating 'disorders' primarily in the anatomy, chemistry or physiology of the body. In accordance with this perspective on sexual matters, physicians look to physical interventions (for example, hormones, drugs, and surgery) to treat any 'abnormalities'. Following the discovery of popular--and profitabl-e-sexuopharmaceuticals such as sildenafil citrate (Viagra) for the treatment of erectile difficulties affecting men, the medical model has gained increasing influence in the domain of sexual health and well-being. However, while medical definitions of--and interventions related to--sexual difficulties are underpinned by an understanding of a 'universal' body (that is, an essential biological body that transcends culture and history), and by the categorisation of the normal and the pathological, the accounts of users of Viagra, and their sexual partners, do not necessarily support such understandings. In some cases, the experiences and perspectives of those affected by erectile difficulties directly challenge the reductionist model of sexuality and sexual experience espoused by medicine. In this paper, we report on a New Zealand study investigating the socio-cultural implications of Viagra, involving 33 men and 27 women discussing the impact of erectile difficulties and Viagra use within relationships. The diverse experiences of participants are discussed in relation to two key issues: the notion of 'sexual dysfunction' itself; and the idea of drugs such as Viagra acting as a 'quick fix' for sexual difficulties affecting men. We argue that the existence of a range of Viagra 'stories' disrupts a simplistic mechanistic portrayal of the male body, male sexuality and 'erectile disorder'. PMID:15144760

  3. Impact of Overactive Bladder Syndrome on Female Sexual Function

    Directory of Open Access Journals (Sweden)

    Serdar Toksöz

    2015-12-01

    Full Text Available The etiology of female sexual dysfunction includes psychological, physiological and iatrogenic causes. Physiological and iatrogenic causes are abdominal surgery, menopause, smoking, spinal cord injuries and some antipsychotic, antihypertensive, and antidepressant drugs. When assessing sexual function, sexual function questionnaires, such as the Female Sexual Function Index, and the Sexual Function Questionnaire are used. The prevalence of female sexual dysfunction is 43% and it has been reported to increase depending on menopause and age. Estrogen, estrogen + testosterone and tibolone, PDE5, apomorphine, bupropion and flibanserin are used in the treatment of female sexual dysfunction. Overactive bladder is a disease affecting the quality of life and is characterized by urgency, frequency, nocturia and urge incontinence with especially filling phase of the bladder resulting from loss of detrusor muscle inhibition. The prevalence of overactive bladder in women in the United States has been reported to be 16.9%. Lower urinary tract symptoms and overactive bladder syndrome are not known how to cause female sexual dysfunction. Menopause and partner status were the most important predictors for female sexual dysfunction. It has been reported that overactive bladder syndrome and urinary incontinence provide prediction of development of female sexual dysfunction. Shame, fear of incontinence, and urinary incontinence as well as urge sensation during sexual intercourse in individuals with overactive bladder syndrome have been reported to be the main factors causing female sexual dysfunction. Pathophysiological relationship between the two disorders has not been elucidated and further clinical and experimental studies are needed in this regard.

  4. Imaging for evaluation of erectile dysfunction

    International Nuclear Information System (INIS)

    Penile erection is a complex phenomenon that includes coordinated intraaction of the nervous, arterial, venous, and sinusoidal systems. A defect in any of these systems may result in erectile dysfunction. Erectile dysfunction is defined as the consistent inability to generate or maintain an erection of sufficient rigidity for sexual intercourse. Although the introduction of sildenafil citrate made the information from imaging studies less critical in the management of the patients with erectile dysfunction, still the imaging studies such as Doppler US, penile arteriography, and cavemosonetry/cavemosography remain the major modalities in the evaluation of erectile dysfunction.

  5. Imaging for evaluation of erectile dysfunction

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seung Hyup [Seoul National University College of Medicine, Seoul (Korea, Republic of)

    2001-03-15

    Penile erection is a complex phenomenon that includes coordinated intraaction of the nervous, arterial, venous, and sinusoidal systems. A defect in any of these systems may result in erectile dysfunction. Erectile dysfunction is defined as the consistent inability to generate or maintain an erection of sufficient rigidity for sexual intercourse. Although the introduction of sildenafil citrate made the information from imaging studies less critical in the management of the patients with erectile dysfunction, still the imaging studies such as Doppler US, penile arteriography, and cavemosonetry/cavemosography remain the major modalities in the evaluation of erectile dysfunction.

  6. The conditioning of human sexual arousal.

    Science.gov (United States)

    O'Donohue, W; Plaud, J J

    1994-06-01

    Although most theories of human sexual behavior claim that much normal sexual behavior is learned, and theories of the etiology and modification of paraphilic and dysfunctional sexual behavior also claim that abnormal sexual behavior is learned and can be counterconditioned, there is no systematic review examining the relationship between conditioning and human sexual behavior. We review research addressing whether habituation, sensitization, classical conditioning, and operant conditioning processes are involved in human sexual behavior. We conclude that, due to the methodological problems of extant studies, the basis for asserting the existence of relationships between habituation, sensitization, classical conditioning, operant conditioning, and sexual behavior is tenuous. PMID:8024444

  7. Amelioration of sexual fantasies to sexual abuse cues in an adult survivor of childhood sexual abuse: a case study.

    Science.gov (United States)

    Wilson, Jane E; Wilson, Keith M

    2008-12-01

    Although sexual dysfunction of childhood sexual abuse survivors has received considerable attention, other sexual difficulties experienced by survivors of CSA, such as sexual fantasies to cues of sexual abuse, have received less attention. In this A-B design case study, a young adult female survivor of childhood sexual abuse presented for treatment at a Midwest rape crisis center. After successful treatment of post-traumatic stress disorder, she complained of unwanted sexual fantasies to sexual abuse cues and concomitant guilt and shame. Following baseline data collection, treatment consisted of self-applied aversion therapy to unwanted sexual arousal to sexual abuse cues. Decrease in sexual arousal to these cues was concurrent with the introduction of treatment. A concomitant decrease in guilt and shame occurred while self-ratings of control increased. PMID:18355799

  8. Challenges in sexual medicine

    DEFF Research Database (Denmark)

    Cellek, Selim; Giraldi, Annamaria

    2012-01-01

    The sexual medicine field has been in mode of revolution until recently. Like all other fields of biomedical research, the economic situation around the world has had a negative impact on the field's momentum-research funding bodies, regulatory bodies and pharmaceutical companies seem to have...... placed sexual medicine in their low-priority list. But this is not the only challenge the field is facing. The successful development of phosphodiesterase type 5 (PDE5) inhibitors for treatment of erectile dysfunction (ED) means that research in this area seems to have slowed. However, there remain...... several unmet medical needs within sexual medicine such as premature ejaculation, severe ED and hypoactive sexual desire disorder, which await novel therapeutic approaches. Despite these challenges, research into finding and developing such therapies is likely to continue in the sexual medicine field...

  9. The evolution of the female sexual response concept: Treatment implications

    OpenAIRE

    Damjanović Aleksandar; Duišin Dragana; Barišić Jasmina

    2013-01-01

    Sexual dysfunctions have been the most prevalent group of sexual disorders and include a large number of populations of both sexes. The research of sexual behavior and treatment of women with sexual distress arises many questions related to differences in sexual response of men and women. The conceptualization of this response in modern sexology has changed over time. The objective of our paper was to present the changes and evolution of the female’s sexual response concept in a summari...

  10. Encompassing Sexual Medicine within Psychiatry: Pros and Cons

    Science.gov (United States)

    Segraves, Robert Taylor

    2010-01-01

    Objective: This article examines the positive and negative aspects of psychiatry encompassing sexual medicine within its purview. Methods: MEDLINE searches for the period between 1980 to the present were performed with the terms "psychiatry," "sexual medicine," and "sexual dysfunction." In addition, sexual medicine texts were reviewed for chapters…

  11. Sexuality and sexual health

    OpenAIRE

    Skoberne, Mihaela

    2015-01-01

    The article describes sexual health in the frames of ther dimensions of health, presents the definition of sexual health by WHO, and stressed the needthat sexuality is dealt with in the frames of nursing care as an integral part of an individual's well-being.

  12. [Impact of aging on sexuality].

    Science.gov (United States)

    Degauquier, C; Absil, A-S; Psalti, I; Meuris, S; Jurysta, F

    2012-01-01

    Numerous authors on sexual behaviors have studied the link between the persistence of a sexually active life and progressive aging. The knowledge of sexual health in the elderly has shown that biological sexual aging is extremely diverse and heterogeneous in men as well as in women, and contradicts the stereotype of age that would inevitably alter the sexual biological response in each human. Sexual diseases (lubrication, dyspareunia, erectile dysfunction, inability to achieve orgasm) and diseases of aging that impact sexual function have a growing incidence but don't never touch 100% of individuals. There is a decline in sexual interest correlated with the life-span, but the negative effects of age on desire are related to health problems. Moreover, sexual desire is more correlated with personal attitudes toward sexuality than with biological factors and diseases. Several predictors account for the pursuit of an active sexuality (including the presence of a partner, good health, having good sexual self-esteem, enjoyable past experience, an attitude that values the importance of sex in couple relationship), but the most decisive factor to successfully face the specific markers of aging is the ability to adapt to a more sensory sexuality, less focused on performance and coitus. PMID:22891587

  13. Childhood Sexual Abuse

    Directory of Open Access Journals (Sweden)

    Evrim Aktepe

    2009-08-01

    Full Text Available Sexual abuse is defined as use of child or adolescent by the adults for satisfying of sexual urges and needs with forcing, threatening or tricking. Sexual abuse can be in the form of sexual abuse without touch, sexual touch, interfemoral intercourse, sexual penetration, and sexual exploitation. The prevalence of sexual abuse is reported as 10-40%. It is seen in female four times more than in males. Abusers are frequently male, only 5-15% of them are female. The abuse by females is usually towards male child. Thirty-fifty percent of abuse cases among child and adolescent are outside the family including strangers or familiar person. Some features of abusers are introvert personality, pedophilic and antisocial personality. Most of the abusers have a history of sexual abuse or aggression during childhood. Sexual intercourse between two people who are not allowed to marry by law is called as incest. Family pattern of incest is defined globally as disorganized and dysfunctional. The most commonly reported familial pattern is rigid and patriarchal family pattern with a harsh father using force quite frequently. The clinical features and impacts of the sexual abuse on the child varies according to the relation between abusers and the child, form of abuse, duration of abuse, presence of physical assault, developmental phase, child age and psychological development before the abuse. Sexual abuse history may result in psychiatric disorders including anxiety, depression, substance dependence, suicide act, borderline personality disorder, posttraumatic stress disorder. Abuse negatively affects interpersonal relationships and self esteem of abused individuals. Several studies reported close association between risky sexual behaviors in adulthood and a history of of sexual abuse during childhood. Four traumatic dynamics including traumatic sexuality with abuse, feeling of betrayal, weakness, and stigmatization exist in childhood abuse. Trauma can cause

  14. [Sexuality in overweight and obesity].

    Science.gov (United States)

    Abrahamian, Heidemarie; Kautzky-Willer, Alexandra

    2016-03-01

    The association between obesity and sexual dysfunction has been described in many studies. Neurobiological, hormonal, vascular and mental disturbances are the main reasons in male and in female gender. Sexual interest and desire, sexual arousal, orgasm, painful intercourse and premature ejaculation can be involved. Data for prevalence of sexual function disturbances in obese people are scarce and most studies were small. For screening of sexual function we recommend the International Index of Erectile Function (IIEF)-Score, which contains 15 Items for males and the Female Sexual Function Index (FSFI), which contains 19 items for females. Treatment of sexual function disturbances include lifestyle changes with an increase of physical activity, weight control, healthy eating and smoking cessation. Testosterone substitution in cases of real hypogonadism and treatment with PDE-5 inhibitors are well documented treatment options in male individuals. New treatment options for female patients with variable effectiveness are fibanserin, testosterone, bupropione and oxytocin. PMID:26811242

  15. The CopenHeartSF trial--comprehensive sexual rehabilitation programme for male patients with implantable cardioverter defibrillator or ischaemic heart disease and impaired sexual function

    DEFF Research Database (Denmark)

    Johansen, Pernille Palm; Zwisler, Ann-Dorthe; Hastrup-Svendsen, Jesper;

    2013-01-01

    Sexuality is an important part of people's physical and mental health. Patients with heart disease often suffer from sexual dysfunction. Sexual dysfunction has a negative impact on quality of life and well-being in persons with heart disease, and sexual dysfunction is associated with anxiety and...... depression. Treatment and care possibilities seem to be lacking. Studies indicate that non-pharmacological interventions such as exercise training and psychoeducation possess the potential of reducing sexual dysfunction in patients with heart disease. The CopenHeartSF trial will investigate the effect of a...

  16. Memory dysfunction.

    Science.gov (United States)

    Amici, Serena

    2012-01-01

    Memory is the cognitive ability that allows to acquire, store and recall information; its dysfunction is called amnesia and can be a presentation of unilateral ischemic stroke in the territory of the posterior cerebral and anterior choroidal artery as well as subarachnoid hemorrhage. PMID:22377863

  17. Defining characteristics, validated by specialists and manifested by patients: a study of the sexual dysfunction and ineffective sexuality pattern diagnoses Características definidoras validadas por especialistas y las manifestadas por pacientes: estudio de los diagnósticos disfunción y estándares de sexualidad ineficaces Características definidoras validadas por especialistas e as manifestadas por pacientes: estudo dos diagnósticos disfunção sexual e padrões de sexualidade ineficazes

    Directory of Open Access Journals (Sweden)

    Alexandra de Souza Melo

    2008-12-01

    Full Text Available This observational and descriptive study was carried out to validate the nursing diagnoses Sexual Dysfunction and Ineffective Sexuality Pattern and relate the relevance of the defining characteristics validated by experts with their incidence in patients. Validation by experts involved 32 specialists and 20 patients to verify clinical evidence. For the diagnosis Sexual Dysfunction, the experts attributed scores higher than 0.80 to seven defining characteristics; for Ineffective Sexuality Pattern, four characteristics received scores between 0.50 and 0.80. The clinical occurrence of these characteristics for the Sexual Dysfunction diagnosis ranged between 55% and 90% of the sample and, for Ineffective Sexuality Pattern, between 30% and 85% of the sample. The study contributed to the improvement of these diagnoses and to careful consideration on their defining characteristics according to experts and as observed in a given clientele.Con los objetivos de realizar la validación de los diagnósticos de enfermería Disfunción Sexual y Estándares de Sexualidad Ineficaces y relacionar la pertinencia de las características definidoras validadas por peritos en la incidencia de las mismas en pacientes, se realizó este estudio de observación y descriptivo. Para la validación por especialistas, se contó con 32 peritos y, para la verificación de las evidencias clínicas con 20 pacientes. Para el Diagnóstico Disfunción Sexual, los peritos atribuyeron puntajes mayores que 0,80 para 7 características definidoras y, para Estándares de Sexualidad Ineficaces, 4 de las características recibieron puntajes entre 0,50 y 0,80. La ocurrencia clínica de esas características para el diagnóstico Disfunción Sexual fue de 55 el 90% de la muestra y para Estándares de Sexualidad Ineficaces fue de 30 el 85% de la muestra. El estudio contribuyó para el perfeccionamiento de esos diagnósticos y reflexionar sobre las características definidoras de los mismos en

  18. [Diagnosis and care of senile sexual problems].

    Science.gov (United States)

    Harima, Katsuki

    2013-10-01

    By aging process, sexual behaviors of elderly people may change. Some changes are normal ones, but may be misunderstood as abnormal by prejudice and ignorance of the senile sexuality. As the sexual function of elderly people is influenced by many factors, evaluation of it should include physical, pharmacological, psychological, and partner relational aspects. By using drug, some sexual dysfunctions may be improved. But treatment should not be focused only on penile-vaginal intercourse. Kissing, touching and other alternative sexual behaviors may be useful for the improvement of the senile sexual problems. PMID:24261217

  19. Sexual Health

    Science.gov (United States)

    ... Youth Risk Behavior Survey Newest CDC data on teen risk behaviors Publications Check here to find the latest sexual ... Health (Medline Plus) Teen Sexual Health (Medline Plus) Teen Sexual Risk Behaviors Sexual Health and HIV/AIDS [1] WHO working ...

  20. Sexual Problems

    Medline Plus

    Full Text Available ... sexual pain disorders, for example, anal pain in homosexual men. Women with female sexual arousal disorder have ... You can optimize the sexual setting by enhancing communication with your partner, promoting non-sexual intimacy, and ...

  1. Sexual Problems

    Medline Plus

    Full Text Available ... or, they can occur all the time. Sexual disorders affect both men and women and are classified into 4 main categories: sexual desire disorders, sexual arousal disorders, orgasmic disorders, and sexual pain ...

  2. SEXUAL DYFUNCTIONS AND SOCIAL CRIMES: ITS EVOLUTIONARY, PSYCHOLOGICAL AND INTELLECTUAL ELEMENTS IN THE MODERN HUMAN MIND.

    OpenAIRE

    Sudhansu Kumar Dash

    2014-01-01

    Sexual dysfunctions are characterized by disturbance in sexual desire and in the psychophysiological changes that characterize the sexual response cycle and cause marked distress and personal difficulty. The paraphilias are characterized by recurrent, intense sexual urges, fantasies or behaviors that involve unusual objects, activities or situations and cause clinically significant distress or impairment in social, occupational or other important areas of functioning. Sexual disor...

  3. Female Sexual Victimization Among College Students: Assault Severity, Health Risk Behaviors, and Sexual Functioning.

    Science.gov (United States)

    Turchik, Jessica A; Hassija, Christina M

    2014-02-01

    The purpose of the present study was to examine the relationship between college women's sexual victimization experiences, health risk behaviors, and sexual functioning. A sample of 309 college women at a mid-sized Midwestern university completed measures assessing sexual victimization, sexual risk taking, substance use behaviors, sexual desire, sexual functioning, prior sexual experiences, and social desirability. Severity of sexual victimization was measured using a multi-item, behaviorally specific, gender-neutral measure, which was divided into four categories based on severity (none, sexual contact, sexual coercion, rape). Within the sample, 72.8% (n = 225) of women reported at least one experience of sexual victimization since age 16. Results from MANCOVAs and a multinomial logistic regression, controlling for social desirability and prior sexual experience, revealed that sexual victimization among female students was related to increased drug use, problematic drinking behaviors, sexual risk taking, sexual dysfunction, and dyadic sexual desire. In addition, findings indicated that women exposed to more severe forms of sexual victimization (i.e., rape) were most likely to report these risk-taking behaviors and sexual functioning issues. Implications for sexual assault risk reduction programming and treatment are discussed. PMID:24505086

  4. Sexual side effects induced by psychotropic drugs

    DEFF Research Database (Denmark)

    Kristensen, Ellids

    2002-01-01

    The majority of psychotropic drugs entail sexual side effects. The sexual side effects may reduce quality of life and may give rise to non-compliance. For example, 30-60 per cent of patients treated with antidepressants are known to develop a sexual dysfunction. However, some psychotropic drugs...... with no or very few sexual side effects have begun to emerge. The treatment of sexual side effects induced by psychotropic drugs may consist of: modified sexual habits, reduction in dosage, switching to another medication, possibly in combination with different psychotropic agents, other varieties of...... pharmacologically active substances or specific products for the treatment of sexual dysfunction such as sildenafil. Above all, it should be acknowledged that relatively few data are available in this field and in particular that there is a lack of controlled studies....

  5. Design and validity of a questionnaire to assess sexuality in pregnant women

    OpenAIRE

    Barbosa Angélica P; Lopes Gerson P; Dias Adriano; Calderon Iracema MP; Rudge Cibele VC; Maestá Izildinha; Odland Jon; Rudge Marilza VC

    2009-01-01

    Abstract Background A review of validated methods for assessing female sexual dysfunction and a review of male and female sexual dysfunction did not refer to any specific questionnaire for evaluating sexuality during pregnancy. A study was performed at the Obstetrics and Gynecology Department of Botucatu Medical School, São Paulo State University, Brazil to design and validate a pregnancy sexuality questionnaire, the Pregnancy Sexual Response Inventory (PSRI). Methods Women with a singleton p...

  6. The Relationship Between Sexual Satisfaction and Education Levels in Women

    Directory of Open Access Journals (Sweden)

    Laleh Pourmousavi

    2013-07-01

    Full Text Available Introduction: Public health’s increasing embrace of sexual life quality promotion is also evidenced by the explosion of sexual rights discourse, including the right to sexual pleasure and pleasure-centered sexual health promotion efforts. Different studies have examined Influence factors on this subject.Method: subjects were 270 married women in the age range of 18-45 years old. Sexual satisfaction and sexual function indexes beside demographic data have evaluated by formal known questioners: Sexual Satisfaction Scale for women (SSS-W and Female Sexual Function Index (FSFI.Result: There was not a lineal relation between sexual satisfaction and formal education level in participant women. Under diploma and doctorate education group have had more sexual dysfunction and lower sexual satisfaction.Conclusion: Higher formal education level necessarily does not bring better sexual function or sexual life satisfaction.

  7. Sexuality After Breast Cancer: Need for Guideline

    Directory of Open Access Journals (Sweden)

    Vaziri Sh

    2012-02-01

    Full Text Available Background: Clinical experiences have revealed that patients with breast cancer experience various sexual problems following their treatment. Breast cancer negatively impacts the sexual life of the afflicted couples, and as a traumatic event can influence women’s psychosexual functioning and intimate relationship. This review focuses on sexuality after breast cancer and on a growing need for bio-psycho-social guidelines for breast cancer treatment. Methods: This study aims to review the literature on management, psychological outcomes and sexual dysfunction in patients with breast cancer. Results: Although the benefits of the current treatment strategies are well established, many cancer survivors are at risk for developing psycho physiological symptoms including sexual dysfunction. Cancer and treatment-related factors can influence sexual functioning. We review current treatment -related side effects on sexual functioning such as desire, arousal and orgasm in breast cancer patients. Despite the impact of medical treatment on survival of patients with breast cancer, no satisfactory steps have been taken towards improving sexual functioning of these patients. Conclusion: Breast cancer affects many aspects of sexuality, including changes in physical functioning and in the perception of feminity. Sexual dysfunction following breast cancer should be diagnosed and managed as a systematic approach with multidisciplinary inputs. Healthcare professionals should assess the effects of medical and surgical treatment on the sexuality of breast cancer survivors.

  8. Effects of hormone treatment on sexual functioning in postmenopausal women: pharmacological intervention and female sexuality

    OpenAIRE

    Nijland, Esmé Aurelia

    2008-01-01

    Effects of hormone treatment on sexual functioning in postmenopausal women. Pharmacological intervention and female sexuality: a complex, controversial clinical and social issue. The studies presented in this thesis have been conducted to investigate the effects of hormone therapy (HT) and tibolone on sexual function in postmenopausal women. Sufficient evidence for the effects of tibolone on sexual function and dysfunction in postmenopausal women was, until now not available. As tibolone does...

  9. Personality Traits, Sexual Problems, and Sexual Orientation: An Empirical Study.

    Science.gov (United States)

    Peixoto, Maria Manuela; Nobre, Pedro

    2016-04-01

    Personality traits, namely neuroticism, have been suggested as vulnerability factors for the development and maintenance of sexual dysfunction in heterosexual samples. However, no evidence was found regarding homosexual samples. This study aimed to analyze the differences on personality traits between heterosexual and homosexual men and women with and without sexual problems. Participants were 285 individuals (142 men, 143 women) who completed a web-based survey. Participants answered the NEO Five-Factor Inventory, the Brief Symptomatology Inventory, and questions regarding sexual problems. The groups of men and women with and without sexual problems were matched for sociodemographic variables. A 2 (Group) × 2 (Sexual Orientation) multivariate analysis of covariance was conducted separately for each gender. Results indicated a significant main effect for group and for sexual orientation in male and female samples. Men with sexual problems scored higher on neuroticism, whereas women with sexual problems scored higher on neuroticism and lower on extraversion when compared with healthy controls, regardless of sexual orientation. In addition, gay men scored higher on neuroticism and lesbian women scored higher on conscientiousness compared with the heterosexual groups. The present findings emphasize the central role of neuroticism on sexual problems in both men and women regardless of sexual orientation. PMID:25405957

  10. The evolution of the female sexual response concept: Treatment implications

    Directory of Open Access Journals (Sweden)

    Damjanović Aleksandar

    2013-01-01

    Full Text Available Sexual dysfunctions have been the most prevalent group of sexual disorders and include a large number of populations of both sexes. The research of sexual behavior and treatment of women with sexual distress arises many questions related to differences in sexual response of men and women. The conceptualization of this response in modern sexology has changed over time. The objective of our paper was to present the changes and evolution of the female’s sexual response concept in a summarized and integrated way, to analyze the expanded and revised definitions of the female sexual response as well as implications and recommendations of new approaches to diagnostics and treatment according to the established changes. The lack of adequate empirical basis of the female sexual response model is a critical question in the literature dealing with this issue. Some articles report that linear models demonstrate more correctly and precisely the sexual response of women with normal sexual functions in relation to women with sexual dysfunction. Modification of this model later resulted in a circular model which more adequately presented the sexual response of women with sexual function disorder than of women with normal sexual function. The nonlinear model of female sexual response constructed by Basson incorporates the value of emotional intimacy, sexual stimulus and satisfaction with the relationship. Female functioning is significantly affected by multiple psychosocial factors such as satisfaction with the relationship, self-image, earlier negative sexual experience, etc. Newly revised, expanded definitions of female sexual dysfunction try to contribute to new knowledge about a highly contextual nature of woman’s sexuality so as to enhance clinical treatment of dysfunctions. The definitions emphasize the evaluation of the context of women’s problematic sexual experiences.

  11. TESTOCAP: A HERBAL SOLUTION FOR ERECTILE DYSFUNCTION AND PREMATURE EJACULATION

    Directory of Open Access Journals (Sweden)

    Satender Tanwar* and Shailaja SV

    2015-03-01

    Full Text Available Sexual activity is a vital principle of human living that connects the desire, energy and pleasure of the body to a knowledge of human intimacy, for the sake of erotic love, intimate friendship, human mating and procreation. Sexuality is the capacity to have erotic experiences and responses. According to Masters and Johnson, the human sexual response cycle consists of four phases: excitement, plateau, orgasm, and resolution. The World Health Organization's International Classifications of Diseases defines sexual problems as "various ways in which an individual is unable to participate in a sexual relationship as he or she would wish". There are four major categories of sexual problems: desire disorders, arousal disorders, orgasmic disorders, and sexual pain disorders. Sexual arousal disorder in men, erectile dysfunction. Erectile dysfunction (ED or impotence is sexual dysfunction characterized by the inability to develop or maintain an erection of the penis during sexual activity.Orgasmic disorders In men, premature ejaculation Premature ejaculation (PE occurs when a man experiences orgasm and expels semen soon after sexual activity and with minimal penile stimulation. Sexuality has been explained in the Ayurveda classics in detail along with the various disorders related to desire, arousal, orgasmic and sexual pain disorders. The various formulations have been explained in classics to relieve these disorders and help the man to enjoy their sexual life.Considering these issues the need of hour this conceptual study has been carried out to help, support and provide enhanced sexual life with readily available pure botanicals which are time tested evidenced based and 100% safe and effective.

  12. Symptoms of Autonomic Dysfunction in Human Immunodeficiency Virus

    OpenAIRE

    Chow, Dominic; Nakamoto, Beau K.; Sullivan, Katherine; Sletten, David M; Fujii, Satomi; Umekawa, Sari; Kocher, Morgan; Kallianpur, Kalpana J; Shikuma, Cecilia M.; Low, Phillip

    2015-01-01

    This retrospective study evaluated the frequencies of symptoms associated with autonomic dysfunction in human immunodeficiency virus (HIV)-infected patients on stable combined antiretroviral therapy. Patients infected with HIV reported higher frequencies of dysautonomia symptoms compared with HIV-negative patients, particularly in the autonomic domains related to urinary, sleep, gastroparesis, secretomotor, pupillomotor, and male sexual dysfunction.

  13. Sexual Health in Hematopoietic Stem Cell Transplant Recipients

    Science.gov (United States)

    Li, Zhuoyan; Mewawalla, Prerna; Stratton, Pamela; Yong, Agnes S.M.; Shaw, Bronwen E.; Hashmi, Shahrukh; Jagasia, Madan; Mohty, Mohamad; Majhail, Navneet S.; Savani, Bipin N.; Rovó, Alicia

    2016-01-01

    Hematopoietic stem cell transplantation (HSCT) plays a central role in patients with malignant and, increasingly, nonmalignant conditions. As the number of transplants increases and the survival rate improves, long-term complications are important to recognize and treat to maintain quality of life. Sexual dysfunction is a commonly described but relatively often underestimated complication after HSCT. Conditioning regimens, generalized or genital graft-versus-host disease, medications, and cardiovascular complications as well as psychosocial problems are known to contribute significantly to physical and psychological sexual dysfunction. Moreover, it is often a difficult topic for patients, their significant others, and health care providers to discuss. Early recognition and management of sexual dysfunction after HSCT can lead to improved quality of life and outcomes for patients and their partners. This review focuses on the risk factors for and treatment of sexual dysfunction after transplantation and provides guidance concerning how to approach and manage a patient with sexual dysfunction after HSCT. PMID:26372459

  14. Endorsement of Models Describing Sexual Response of Men and Women with a Sexual Partner

    DEFF Research Database (Denmark)

    Giraldi, Annamaria; Kristensen, Ellids; Sand, Michael

    2015-01-01

    Function Index, Female Sexual Distress Scale, and the International Index of Erectile Function were used to describe sexual function. Also, participants completed questionnaires with written descriptions of different sexual responses to describe their most experienced sexual response. MAIN OUTCOME MEASURE......: For women, we measured desire, arousal, lubrication, orgasm, sexual satisfaction, pain during sexual activity, sexual distress, and satisfaction with sexual life. For men, we measured erectile function, orgasm, desire, intercourse satisfaction, overall satisfaction, and satisfaction with sexual life...... none of the models. Among women, 34% endorsed the Kaplan model, 28% the Masters & Johnson model, 25.6% the Basson model, and 12.5% none of the models. Among women, sexual dysfunction and distress were significantly (P = 0.01) related to endorsement of the Basson model or none of the models. Among men...

  15. Dysfunctional voiding.

    Science.gov (United States)

    Chiozza, M L

    2002-01-01

    Wetting may be considered the Cinderella of paediatric medicine. Before discussing dysfunctional voiding, the milestones of the normal development of continence in the child and the definitions used to describe this topic are presented. Bladder storage requires (1): accommodation of increasing volumes of urine at low intravesical pressure and with appropriate sensation; (2): a bladder outlet that is closed and not modified during increase in intra-abdominal pressure; (3): absence of involuntary bladder contractions. Development of continence in the child involves three independent factors maturing concomitantly: (1) development of normal bladder capacity; (2) maturation of urethral sphincter function; (3) development of neural control over bladder-sphincter function. All these processes are discussed. Abnormalities of any of these maturational sequences, which run parallel and overlapping, may result in clinically evident abnormalities of bladder sphincter control. Although dysfunctional voiding (DV) in children is very common its prevalence has not been well studied and, to date, and its origin is not well known. In a correct evaluation of functional voiding we must take into account different elements: the bladder capacity (that increases during the first 8 years of life roughly 30 ml per year), the micturition frequency, post-void residual volumes, bladder dynamics, urinary flow rates. Thus the correct assessment of children with lower urinary tract dysfunction should include a detailed history. Signs of DV range from urge syndrome to complex incontinence patterns during the day and the night. In addition to incontinence problems, children may have frequency, urgency, straining to void, weak or interrupted urinary stream, urinary tract infections (UTIs) and chronic constipation with or without encopresis. DV are also referred in enuretic children who wet the bed more than one time per night and have a functional bladder capacity lower than attended for age

  16. AB271. Sexual dysfunction in chronic prostatitis

    OpenAIRE

    Cho, In-Rae

    2016-01-01

    Chronic prostatitis/ chronic pelvic pain syndrome (CP/CPPS), or NIH category III prostatitis, is a clinical syndrome characterized by genital/ pelvic pain and lower urinary tract symptoms in the absence of urinary tract infection. CPPS is the most common prostatic disease in men younger than 50 years of age and the third most common in men older than 50 years of age. CP/CPPS is a complex entity with unclear etiology. Many articles reported that the high percentage of patients with CP/CPPS had...

  17. Sexual dysfunction in women with diabetes mellitus

    DEFF Research Database (Denmark)

    Giraldi, Annamaria; Kristensen, Ellids

    2010-01-01

    Diabetes mellitus (DM) is an increasing health concern throughout the world. DM is categorized as either type 1 (DM-1) or type 2 (DM-2), where DM-1 represents a lack of insulin production, and DM-2 is characterized by a relative lack of insulin (i.e., decreased sensitivity to the effect of insulin...

  18. Management of erectile dysfunction in hypertension: Tips and tricks

    OpenAIRE

    Viigimaa, Margus; Vlachopoulos, Charalambos; Lazaridis, Antonios; Doumas, Michael

    2014-01-01

    Arterial hypertension is a major risk factor for cardiovascular disease and affects approximately one third of the adult population worldwide. The vascular origin of erectile dysfunction is now widely accepted in the vast majority of cases. Erectile dysfunction is frequently encountered in patients with arterial hypertension and greatly affects their quality of life of hypertensive patients and their sexual partners. Therefore, the management of erectile dysfunction in hypertensive patients i...

  19. Low Back Pain And Sexuality

    OpenAIRE

    KURU, Ö.; BEWYER, D.; KUTLU, Y.

    2010-01-01

    Sexual dysfunction in the patient with chronic low back pain is a frequently misunders¬tood and neglected aspect of this disease classification. Clinical experience and a review of the literature defines three causative factors: primary organic pathology interrupting nor¬mal nervous system function; side effects of medication prescribed for the condition, and psychological factors relating to anxiety over performance and fear of pain during sexual activity. The purpose of this article is to d...

  20. Sexual Problems

    Medline Plus

    Full Text Available ... and are classified into 4 main categories: sexual desire disorders, sexual arousal disorders, orgasmic disorders, and sexual pain disorders. ... is having little or no sexual fantasies and desire for sexual activity. This lack of desire is beyond what ...

  1. Radiotherapy for prostate cancer and sexual health

    NARCIS (Netherlands)

    L. Incrocci (Luca)

    2015-01-01

    textabstractSexual dysfunction is very common after treatment of prostate cancer. Radiation therapy together with radical prostatectomy is the most effective treatment for localized disease. Percentages of erectile dysfunction (ED) reported in prospective studies after external-beam radiotherapy (RT

  2. Developmental Risk Factors for Sexual Offending.

    Science.gov (United States)

    Lee, Joseph K. P.; Jackson, Henry J.; Pattison, Pip; Ward, Tony

    2002-01-01

    A study involving 64 Australian sex offenders and 33 non-sex offenders found childhood emotional abuse and family dysfunction, childhood behavior problems, and childhood sexual abuse were developmental risk factors for paraphilia. Emotional abuse and family dysfunction was found to be a risk factor for pedophilia, exhibitionism, rape, or multiple…

  3. Sexual traumatic events and neurotic disorders picture – sexuality-related and sexuality-unrelated symptoms

    Directory of Open Access Journals (Sweden)

    Rutkowski, Krzysztof

    2013-06-01

    trauma is mainly focused on the area of sexual dysfunctions.

  4. Neurodevelopmental Biology Associated with Childhood Sexual Abuse

    Science.gov (United States)

    De Bellis, Michael D.; Spratt, Eve G.; Hooper, Stephen R.

    2011-01-01

    Child maltreatment appears to be the single most preventable cause of mental illness and behavioral dysfunction in the United States. Few published studies examine the developmental and the psychobiological consequences of sexual abuse. There are multiple mechanisms through which sexual abuse can cause post-traumatic stress disorder, activate…

  5. Sexual Hypnotherapy for Couples and Family Counselors.

    Science.gov (United States)

    Araoz, Daniel; Burte, Jan; Goldin, Eugene

    2001-01-01

    Presents the utilization of Ericksonian hypnotic techniques in conjunction with cognitive behavioral techniques collectively labeled the New Hypnosis, as they apply to the treatment of male and female sexual dysfunction within a counseling setting. Specific techniques to improve functioning throughout the five stages of sexual response are…

  6. Relationship satisfaction and sexuality in Huntington's disease.

    Science.gov (United States)

    Reininghaus, Eva; Lackner, Nina

    2015-01-01

    Huntington's disease (HD) is a chronic disabling disease that inflicts a considerable burden on patients and their families for a variety of reasons. These reasons include cognitive impairment and motor dysfunction, personality changes, and knowledge of possible genetic transmission of the disease to their children. Thus, the decision to take a genetic test for individuals at risk for HD is often associated with family planning and relationship stress. However, for most individuals, a positive genetic test does not alter family planning with regard to their decision to have children. HD has also been associated with abnormal sexual behaviors, although only a few studies have explored sexuality and sexual dysfunction in HD. Up to 85% of men and 75% of women experience sexual problems, including hypoactive sexual disorder in some cases and increased sexual interest and paraphilia in others. Psychologic support should involve the communication of realistic expectations about the progression of the disorder and potential consequences on the children. PMID:26003252

  7. Childhood Sexual Abuse: Long-Term Effects on Psychological and Sexual Functioning in a Nonclinical and Nonstudent Sample of Adult Women.

    Science.gov (United States)

    Greenwald, Evan; And Others

    1990-01-01

    Comparison of psychological and sexual functioning of 54 women sexually abused as children and 54 nonabused women found no differences in self-esteem, but abused women reported more symptoms of distress and psychological symptoms previously associated with sexual abuse. No differences in self-reported sexual satisfaction or dysfunction were found.…

  8. Healthy Sexuality

    Medline Plus

    Full Text Available ... safe sexual experiences, free of coercion, discrimination and violence. For sexual health to be attained and maintained, the sexual rights of all persons must be respected, protected and ...

  9. Healthy Sexuality

    Medline Plus

    Full Text Available ... anxiety, depression, stress, abuse, and poor body image. Memories of a sexual trauma can greatly influence how a person functions sexually. Social and interpersonal factors that can affect sexual function include relationship problems, religious beliefs, cultural ...

  10. Sexual Problems

    Medline Plus

    Full Text Available ... You can optimize the sexual setting by enhancing communication with your partner, promoting non-sexual intimacy, and finding ways to keep sex special and exciting. Sexual aids include lubricants, moisturizers, ...

  11. Sexual Problems

    Science.gov (United States)

    ... You can optimize the sexual setting by enhancing communication with your partner, promoting non-sexual intimacy, and finding ways to keep sex special and exciting. Sexual aids include lubricants, moisturizers, ...

  12. Sexual Problems

    Medline Plus

    Full Text Available ... genital contact with a sexual partner and the person feels disgust and revulsion towards sexual activity. The ... which is similar to what happens when a person has a phobia or fear. Hypoactive sexual desire ...

  13. Sexual Problems

    Medline Plus

    Full Text Available ... or constant. Sexual disorders can affect men and women and are classified into four categories: desire disorders, ... the time. Sexual disorders affect both men and women and are classified into 4 main categories: sexual ...

  14. Healthy Sexuality

    Medline Plus

    Full Text Available ... produces increased intensive sexual excitement and that produces sexual desire that she may not have had at first. Sometimes people worry about their sexual health and function. If you have these concerns, ...

  15. Sexual Assault

    Science.gov (United States)

    Sexual assault is any sexual activity to which you haven't freely given your consent. This includes completed ... trust, a friend, an acquaintance, or a stranger. Sexual assault can affect your health in many ways. It ...

  16. Healthy Sexuality

    Medline Plus

    Full Text Available ... a state of physical, emotional, mental and social well-being in relation to sexuality; it is not ... respectful approach to sexuality and sexual relationships, as well as the possibility of having pleasurable and safe ...

  17. Sexual Problems

    Medline Plus

    Full Text Available ... and Smoking Cessation Links to Professional Societies and Organizations Home › Sexual Problems Sexual concern causing distress can ... such as sexual abuse can be involved as well. Pain caused by lack of lubrication or by ...

  18. Sexual Problems

    Medline Plus

    Full Text Available ... concerns with your sexual partner. Because they are complex, sexual concerns are treated in many different ways. ... a healthcare professional. Although sexual problems can be complex, there are a variety of treatments that can ...

  19. Healthy Sexuality

    Medline Plus

    Full Text Available ... provider or sexual counselor. Let’s begin with some definitions and explanations. Sexuality is the experience and/or ... health to be attained and maintained, the sexual rights of all persons must be respected, protected and ...

  20. The impact of primary Sjogren's syndrome on female sexual function

    NARCIS (Netherlands)

    van Nimwegen, Jolien F.; Arends, Suzanne; van Zuiden, Greetje S.; Vissink, Arjan; Kroese, Frans G. M.; Bootsma, Hendrika

    2015-01-01

    Objective. Prevalence of vaginal dryness and dyspareunia is high in women with primary SS (pSS). Our aim was to compare sexual function and sexual distress in women with pSS with healthy controls, as well as to assess parameters that are associated with sexual dysfunction and distress in pSS. Method

  1. Brain Networks during Free Viewing of Complex Erotic Movie: New Insights on Psychogenic Erectile Dysfunction

    OpenAIRE

    Cera, Nicoletta; Di Pierro, Ezio Domenico; Ferretti, Antonio; Tartaro, Armando; Romani, Gian Luca; Perrucci, Mauro Gianni

    2014-01-01

    Psychogenic erectile dysfunction (ED) is defined as a male sexual dysfunction characterized by a persistent or recurrent inability to attain adequate penile erection due predominantly or exclusively to psychological or interpersonal factors. Previous fMRI studies were based on the common occurrence in the male sexual behaviour represented by the sexual arousal and penile erection related to viewing of erotic movies. However, there is no experimental evidence of altered brain networks in psych...

  2. The Effect of Sexual Cognitive-Behavioral Therapy on Females\\' Sexual Knowledge, Sexual Attitude, and Sexual Self-Confidence. A Case Study in Shiraz, Iran

    OpenAIRE

    Rahimi, E; A Shafiabadi; F Yunesi

    2009-01-01

    1.Nikkhoo MR. Avadais yance, Hamayak. Females Sexual life. 4th ed.Tehran: sokhan 2001 9-10. 2.Warnock JJ. Female hypoactive sexual desire disorder: epidemiology, diagnosis and treatment. CNS Drugs 200216(11):745-53. 3.Spence SH. Psychosexual therapy. Translation by Hassan tuzandejani, 1380. 3th ed. Tehran: Peyk farhang 199110. 4.Arman S. Females sexual dysfunction comparison between pre and post menopause. Journal of Arak university of medicine 2005 8(3):2-7. 5.Besharat MA. Sexu...

  3. The Irish Study of Sexual Health and Relationships Main Report

    OpenAIRE

    Layte, Richard; McGee, Hannah; Quail, Amanda; Rundle, Kay; Cousins, Grainne; Donnelly, Claire; Mulcahy, Fiona; Conroy, Ronán

    2006-01-01

    SEX and sexuality are core dimensions of the human experience and an important determinant of well-being. An individual’s sexual behaviour and sexual health cannot be separated from their social and cultural context. This is brought out in the World Health Organisation’s (WHO) definition of sexual health. It is concerned not just with the absence of disease or dysfunction but with a broad definition of health: “Sexual health requires a positive and respectful approach to sexuality and sexual ...

  4. A new therapeutic approach for erectile dysfunction: Low intensity shockwaves

    Directory of Open Access Journals (Sweden)

    García-Perdomo, Herney Andrés

    2015-07-01

    Full Text Available Erectile dysfunction is the inability to achieve or sustain a penile erection for vaginal penetration and satisfactory sexual performance. It is the second most frequent problem of sexual dysfunction in men, after premature ejaculation, with an approximate prevalence rate of 30%. Most cases of erectile dysfunction have an organic origin, mostly vascular diseases, but it is also associated with psychological, neurological, and hormonal factors, or with structural alterations of the penis. Therapy with 5-phosphodiesterase inhibitors has been clinically effective, but some patients do not respond to it. Lowintensity shock waves may improve penile vascularity and blood flow, leading to better erections, and improvement of the quality of sexual performance. In this review several studies are included that show the effectiveness of this treatment for erectile dysfunction.

  5. Androgens and sexuality.

    Science.gov (United States)

    Hutchinson, K A

    1995-01-16

    A review of the literature reveals that the endocrine determinants of female sexuality are complex and difficult to characterize. In adolescent males, free testosterone directly affects sexual motivation, with social factors exerting little or no effect. In adolescent girls, by contrast, societal and peer pressure play a pivotal role in the appearance of certain sexual behaviors. Throughout a woman's life, hormonal and psychosocial factors are critical influences. It is possible that cyclic patterns of testosterone are less important for female sexual behavior than the "tonic" effect of overall testosterone levels. Although the estrogen dependence of the vaginal epithelium--important for postmenopausal women--has been clearly established, the role of other hormonal factors and treatments, particularly those involving androgens, in human female sexual behavior remains enigmatic. The search for an understanding of these relationships is not merely an interesting academic exercise but is necessary to determine what role, if any, androgens may play in the treatment of sexual dysfunction during the female reproductive years. PMID:7825630

  6. Perspectives on Sexual Health and Function of Recent Male Combat Veterans of Iraq and Afghanistan

    OpenAIRE

    Helmer, Drew A.; Beaulieu, Gregory; Powers, Catherine; Houlette, Cheryl; Latini, David; Kauth, Michael

    2015-01-01

    Background U.S. veterans of recent wars in Iraq and Afghanistan may be at greater risk for sexual dysfunction due to injuries, mental health conditions, medications used to treat those conditions, and psychosocial factors. Objective To explore the perceptions of recent Veterans about sexual health and dysfunction, contributing factors, its impact and solutions. Design Qualitative study. Participants Eight men who screened positive for sexual dysfunction at initial presentation to a postdeploy...

  7. [Eating disorders and sexual function].

    Science.gov (United States)

    Kravvariti, V; Gonidakis, Fr

    2016-01-01

    groups of patients report more often than general population a lack of satisfaction from their sexual experiences. Other factors that are common to eating disorders and sexual dysfunction are personality traits, negative body-image, adverse childhood experiences, negative family climate and especially early traumatic experiences such as sexual abuse. Furthermore, comorbidity of eating disorders with depression may have a negative impact on the patient's sexual function. The treatment and improvement of sexual behavior is quite problematic when the patient is also suffering from an eating disorder. Eating Disorder patients are often very reluctant to discuss their sexual life with the therapist and to engage in any kind of therapeutic intervention. Comorbidity with a number of other disorders makes psychotherapy even more difficult for those patients. Furthermore, a considerable percentage of Anorexia Nervosa patients do not have any kind of sexual activity, at least until nutrition and weight are restored. PMID:27467034

  8. Perceived causes and consequences of sexual changes after cancer for women and men: a mixed method study

    OpenAIRE

    Ussher, Jane M; Perz, Janette; Gilbert, Emilee; ,

    2015-01-01

    Background Previous research on cancer and sexuality has focused on physical aspects of sexual dysfunction, neglecting the subjective meaning and consequences of sexual changes. This has led to calls for research on cancer and sexuality to adopt an “integrative” approach, and to examine the ways in which individuals interpret sexual changes, and the subjective consequences of sexual changes. Method This study examined the nature and subjective experience and consequences of changes to sexual ...

  9. A holistic approach to psychological sexual problems in women with diabetic husbands

    OpenAIRE

    Anahita Khodabakhshi Koolaee; Edalat Asadi; Ladan Mansoor; Leili Mosalanejad; Ali FathAbadi

    2014-01-01

    Background: One of negative and influential factor to chronic diseases is creation of sexual problems in the couple's sexual relationship. Sexual health is one of the most important factor in Sexual and marital satisfaction. Objective: This study aims to compare the relationship between couple burnout, sexual assertiveness, and sexual dysfunctional beliefs in women with diabetic and non-diabetic husbands. Materials and Methods: This cross sectional descriptive study was a causal comparative o...

  10. Sexual Problems

    Medline Plus

    Full Text Available ... and Smoking Cessation Links to Professional Societies and Organizations Home › Sexual Problems Sexual concern causing distress can ... You can optimize the sexual setting by enhancing communication with your partner, promoting non-sexual intimacy, and ...

  11. Sexual Assault

    Science.gov (United States)

    ... been sexually assaulted. 6 , 7 Read more about violence in same-sex relationships . Sexual assault can happen to anyone of any age, race or ethnicity, religion, ability, appearance, sexual orientation, or gender identity. However, women have higher rates of sexual ...

  12. Healthy Sexuality

    Medline Plus

    Full Text Available ... reducing stress, improving self-esteem, and cardiovascular health. A person’s physical sexual response is an important part ... his or her sexuality. Let’s talk about how a woman’s body responds to sexual stimulation. During sexual ...

  13. Synaesthesia and Sexuality: The influence of synaesthetic perceptions on sexual experience

    Directory of Open Access Journals (Sweden)

    MarkusZedler

    2013-10-01

    Full Text Available Introduction. Synaesthesia is a phenomenon in which a certain stimulus induces a concurrent sensory perception; it has an estimated prevalence of 4 %. Sexual arousal as an inducer for synaesthetic perceptions is rarely mentioned in the literature but can be found sometimes in case reports about subjective orgasmic experiences. Aims. To examine whether synaesthetic perceptions during sexual intercourse have an impact on the sexual experience and the extent of sexual trance compared to non-synaesthetes. Methods. In total, 19 synaesthetes with sexual forms of synaesthesia (17 female; 2 male were included as well as corresponding control data of 36 non-synaesthetic subjects (n = 55. Two questionnaires were used to assess relevant aspects of sexual function and dysfunction (a German adaption of the Brief Index of Sexual Functioning, KFSP as well as the occurrence and extent of sexual trance (german version of the Altered States of Consciousness Questionnaire, OAVAV. Additionally qualitative interviews were conducted in some subjects to further explore the nature of sexual experiences in synaesthetes. Main Outcome Measures. Sexual experience and extent of sexual trance during intercourse. Results. Synaesthetes depicted significantly better overall sexual function on the KFSP with increased scores for the subscale “sexual appetence” but coevally significant lower subscale scores for “sexual satisfaction”. Sexual dysfunction was not detected in this sample. Synaesthetes depicted significantly higher levels of the subscales “oceanic boundlessness” and “visionary restructuralization” than controls using the OAVAV. Qualitative interviews revealed varying synaesthetic perceptions during the different states of arousal. Furthermore, synaesthetes reported an unsatisfactory feeling of isolation caused by the idiosyncratic perceptions. Conclusions. Synaesthetes with sexual forms of synaesthesia seem to experience a deeper state of sexual trance

  14. Sexual function among married menopausal women in Amol (Iran)

    OpenAIRE

    Shabnam Omidvar; Fatemeh Bakouie; Fatemeh Nasiri Amiri

    2011-01-01

    Background: Sexual activity is an important part of the human being's life but this instinct could be influenced by some factors such as diseases, drug using, aging, and menopause. But information about that is limited. Aim: The aim of this study is to determine the status of sexual activity among married menopausal women in Amol, Iran. Materials and Methods: This descriptive analytical study was conducted to describe the sexual activity and sexual dysfunction of women after menopause. Data w...

  15. Sexual function in lithium-treated manic-depressive patients

    DEFF Research Database (Denmark)

    Kristensen, Ellids; Jørgensen, Per

    1987-01-01

      Sexual function in 24 patients with major affective disorders who were given prophylactic lithium treatment was compared with that of a control group of surgical outpatients with no known psychiatric disease. Changes in sexual function during lithium treatment were also recorded retrospectively....... Sexual dysfunctions were described by about one-fourth of both female patients and controls. About one-third of the male patients and controls reported sexual dysfunctions. We cannot exclude tha lithium in combination with other psychotropic drugs may increase the frequency of sexual dysfunction. Changes...... in sexual function during lithium treatment were reported by one-fourth of the patients. Of these, four reported a positive influence of the treatment and five a negative influence. Statistically, significantly more patients than controls were dissatisfied with their present sex life....

  16. The Effect of Cognitive-Behavioral Teaching on Improvement of Women's Sexual Function with Hypoactive Sexual Desire Disorder

    OpenAIRE

    Najme-Sadat Hajivosough; Jahanshir Tavakolizadeh; Alireza Rajayi; Alireza Atarodi

    2012-01-01

    Background: Hypoactive sexual desire disorder as the most prevalent sexual dysfunction has a major role in marital relationships. The purpose of this study was to determine the effect of cognitive-behavioral teaching on improvement of women sexual function.Materials and Methods: In this semi experimental study, the sample size were 30 women that 15 were randomly selected for each experimental and control group of women with hypoactive sexual desire. At first the pretest was carried out in bot...

  17. Pharmacogenomics and sexuality: a vision.

    Science.gov (United States)

    Nappi, R E; Domoney, C

    2013-08-01

    Female sexual dysfunction (FSD) is multidimensional with a complex interplay of biopsychosocial factors modulating the clinical expression of sexual symptoms and associated distress. During the entire reproductive lifespan, intra- and interpersonal experiences shape human neuroendocrine and neurovascular sexual pathways. These are dependent on genetic and epigenetic mechanisms, including acquired medical conditions. Understanding the genetic basis of FSD can help to determine clinical phenotypes of women and therefore postulate the most effective intervention according to biological, psychological or environmental determinants. However, there is a paucity of studies demonstrating a genetic contribution to FSD and a diverse modulation of innate and acquired factors on discrete domains of sexual response and distress. This is evident from menarche to menopause. Pharmacogenomics is still in its infancy in the field of sexual medicine and most data regarding genetic polymorphisms of drug targets associated with susceptibility to sexual dysfunction have been obtained in males. Pharmacogenomics may be the future of medical practice in women with FSD and may guide an individualized approach by predicting both therapeutic effects at varying dosages of hormonal and non-hormonal agents, and disadvantageous side-effects and drug interactions. PMID:23848488

  18. Study of men sexual formula. Chapter 8

    International Nuclear Information System (INIS)

    Analysis of average indexes of men sexual formula (MSF) for liquidators was carried out. It was shown, that with increasing of radiation doses acting on personnel the suppressing of their sexual functions is growing up. With increasing of absorbed dose the frequency of copulative cycle disorders is increase from 61.5±5.10 % to 85.72±5.08 %. With increase of age the gradations of MSF indexes characterizing different sides of sexual life is decreasing. Received data evident that patients suffered from radiation action during a month characterizing with pronounced and prolonged dysfunction in sexual sphere

  19. Sexual Problems

    Medline Plus

    Full Text Available ... phosphodiesterase inhibitors, which are drugs often used for erectile dysfunction, and other medications. For women estrogen can be ... vardenafil, and tadalafil, are approved for treatment of erectile dysfunction in men. Women who were given sildenafil in ...

  20. Time Out from Sex or Romance: Sexually Experienced Adolescents' Decisions to Purposefully Avoid Sexual Activity or Romantic Relationships.

    Science.gov (United States)

    Byers, E Sandra; O'Sullivan, Lucia F; Brotto, Lori A

    2016-05-01

    Researchers have given significant attention to abstinence among adolescents, but far less is known about purposeful avoidance of sexual activity (and relationship involvement). Typically, it is assumed that, once adolescents have initiated sexual activity, they will thereafter engage in sexual activity if given the opportunity. However, it is unclear whether that is true as some research indicates that many adolescents engage in sexual activity intermittently. Sexually experienced adolescents may purposefully avoid engaging in sexual activity for a period of time and, if so, this has implications for understanding their sexual decision-making. We used a mixed methods approach to investigate sexually experienced adolescents' decisions to purposefully avoid further sexual activity and/or romantic relationships with a focus on how common these decisions are and factors influencing them. Participants were 411 (56 % female) adolescents (16-21 years old) who completed an on-line survey that assessed reasons for each type of avoidance, religiosity, sexual esteem, sexual distress, sexual coercion, and dysfunctional sexual beliefs. Overall, 27 % of participants had engaged in sexual avoidance and 47 % had engaged in romantic avoidance. Significantly more female than male adolescents reported sexual and romantic avoidance. Adolescents' reasons for sexual avoidance included: lack of sexual pleasure or enjoyment, relationship reasons, negative emotions, values, fear of negative outcomes, negative physical experience, and other priorities. Reasons for romantic avoidance included: effects of previous relationship, not interested in commitment, wrong time, other priorities, negative emotions, no one was good enough, and sexual concerns. Logistical regressions were used to assess associations between age, religiosity, sexual esteem, sexual distress, experience of sexual coercion, and dysfunctional sexual beliefs and having engaged in romantic and/or sexual avoidance. The

  1. Sexual Problems

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    Full Text Available ... You can optimize the sexual setting by enhancing communication with your partner, promoting non-sexual intimacy, and ... devices. Vibrators and dildos can be used by men and women to increase sensation to the genitals. ...

  2. Sexual Problems

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    Full Text Available ... You can optimize the sexual setting by enhancing communication with your partner, promoting non-sexual intimacy, and ... Reproductive Medicine. All Rights Reserved. ASRM Non Discrimination Policy | ASRM Web Site Terms & Conditions of Use | Web ...

  3. Healthy Sexuality

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    Full Text Available ... body may return to its unexcited state, called resolution. There are also physical changes during the sexual ... the body returns to its unaroused stated, called resolution. “Normal” sexual function has been described in many ...

  4. Sexual Problems

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    Full Text Available ... sexual problems. This specialist may be a physician, psychologist, social worker, or physical therapist. You may also ... see” their actions. In addition to improving sexual function, pelvic floor muscle rehabilitation can improve pelvic pain ...

  5. Sexual Problems

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    Full Text Available ... find it helpful to discuss your concerns with your sexual partner. Because they are complex, sexual concerns are treated in many different ways. Often, multiple types of treatment may be required and are used ...

  6. Sexual Problems

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    Full Text Available ... Smoking Cessation Links to Professional Societies and Organizations Home › Sexual Problems Sexual concern causing distress can be ... Find a Health Care Provider Back to Top Home | About Us | Reproductive Health Topics | News & Publications | Resources ...

  7. Sexual Problems

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    Full Text Available ... pain disorders. If you are experiencing problems viewing this embedded video, please click here . Transcript Disorders of ... no sexual fantasies and desire for sexual activity. This lack of desire is beyond what normally happens ...

  8. Sexual Problems

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  9. Sexual Violence

    Science.gov (United States)

    Sexual Violence Facts at a Glance 2012 Adults In a nationally representative survey of adults: 1 • Nearly 1 in ... 5.6% and 5.3%, respectively) experienced sexual violence other than rape, such as being made to ...

  10. Sexual Problems

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    Full Text Available ... such as chronic testicular pain, and 4) other causes of sexual pain that include conditions of the ... should be taken seriously. When a sexual problem causes you distress, don’t be afraid to talk ...

  11. Sexual Problems

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  12. Sexual Problems

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    Full Text Available ... or HSDD, is having little or no sexual fantasies and desire for sexual activity. This lack of ... Top Home | About Us | Reproductive Health Topics | News & Publications | Resources Site endowed by Advanced Reproductive Care, Inc. ( ...

  13. Sexual Problems

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    Full Text Available ... You can optimize the sexual setting by enhancing communication with your partner, promoting non-sexual intimacy, and ... studies are needed to confirm its efficacy and safety. For men with low testosterone levels, there is ...

  14. Sexual Problems

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    Full Text Available ... such as chronic testicular pain, and 4) other causes of sexual pain that include conditions of the penis, such as phimosis or a tight frenulum, and other types of sexual pain disorders, for example, anal pain ...

  15. Sexual Problems

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    Full Text Available ... sexual pain disorders. We’ll discuss each of these briefly. Sexual aversion disorder is an intense dislike ... with placebo.. Larger studies are needed to confirm these findings. Another antidepressant, flibanserin, was recently rejected for ...

  16. Sexual Problems

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    Full Text Available ... You can optimize the sexual setting by enhancing communication with your partner, promoting non-sexual intimacy, and ... with placebo and was associated with several side effects. Phosphodiesterase inhibitors such as sildenafil, vardenafil, and tadalafil, ...

  17. Healthy Sexuality

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    Full Text Available ... to its unaroused stated, called resolution. “Normal” sexual function has been described in many ways by different investigators. Most people think about sexual function as described by Masters and Johnson in the ...

  18. Sexual Problems

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    Full Text Available ... age. It can be situational or constant. Sexual disorders can affect men and women and are classified into four categories: desire disorders, arousal disorders, orgasmic disorders, and sexual pain disorders. ...

  19. Sexual Problems

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    Full Text Available ... concerns with your sexual partner. Because they are complex, sexual concerns are treated in many different ways. ... type of psychotherapy that focuses on how one’s thinking influences feelings and behavior. Sensate focus exercises are ...

  20. Healthy Sexuality

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    Full Text Available ... the course of a lifetime. The World Health Organization has defined sexual health as “…a state of physical, emotional, mental and social well-being in relation to sexuality; it is not ...

  1. Sexual Problems

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    Full Text Available ... If you have a sexual concern, it is important to know that help is available. Share your ... for the treatment of vulvodynia. Sex is an important part of your life and sexual concerns should ...

  2. Healthy Sexuality

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  5. Healthy Sexuality

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    Full Text Available ... pleasurable and safe sexual experiences, free of coercion, discrimination and violence. For sexual health to be attained ... for Reproductive Medicine. All Rights Reserved. ASRM Non Discrimination Policy | ASRM Web Site Terms & Conditions of Use | ...

  6. Sexual Difficulties

    Science.gov (United States)

    ... difficulties Explore other publications and websites Age Page: Sexuality in Later Life - This brochure describes the normal ... effects of illness, disability, and emotional concerns of sexuality in later life. Atrophic Vaginitis (Copyright © UCLA Health ...

  7. Healthy Sexuality

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    Full Text Available ... how a person functions sexually. Social and interpersonal factors that can affect sexual function include relationship problems, religious beliefs, cultural beliefs, and one’s upbringing. Sex is an important ...

  8. Sexual Problems

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    Full Text Available ... of low desire in women, there is some evidence that it may improve sexual experiences in postmenopausal ... men with low testosterone levels, there is some evidence that testosterone therapy may improve sexual function. A ...

  9. Sexual Problems

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    Full Text Available ... aroused and feels sexual arousal from non-genital stimulation, but she lacks physiologic arousal or vaginal congestion, ... premature ejaculation, a man ejaculates with minimal sexual stimulation before, on, or shortly after penetration. This can ...

  10. Healthy Sexuality

    Medline Plus

    Full Text Available ... improving self-esteem, and cardiovascular health. A person’s physical sexual response is an important part of his ... may play a role include anxiety, depression, stress, abuse, and poor body image. Memories of a sexual ...

  11. Female sexuality

    OpenAIRE

    Rao, T.S. Sathyanarana; Nagaraj, Anil Kumar M.

    2015-01-01

    Sex is a motive force bringing a man and a woman into intimate contact. Sexuality is a central aspect of being human throughout life and encompasses sex, gender identities and roles, sexual orientation, eroticism, pleasure, intimacy, and reproduction. Sexuality is experienced and expressed in thoughts, fantasies, desires, beliefs, attitudes, values, behaviors, practices, roles and relationships. Though generally, women are sexually active during adolescence, they reach their peak orgasmic fre...

  12. Infantile sexuality

    DEFF Research Database (Denmark)

    Zeuthen, Katrine Egede; Gammelgård, Judy

    2010-01-01

    When first presented, Freud´s theory of infantile sexuality was a scandal. Not only was the claim that the small child sucking at the mother´s breast experiences a kind of pleasure that Freud without hesitation named sexual, the theory also turned the common understanding of human sexuality up-si...

  13. Healthy Sexuality

    Medline Plus

    Full Text Available ... self-esteem, and cardiovascular health. A person’s physical sexual response is an important part of his or ... talk about how a woman’s body responds to sexual stimulation. During sexual arousal, blood flow increases to ...

  14. Healthy Sexuality

    Medline Plus

    Full Text Available ... shown that a women’s response intertwines both her physical and emotional sexual drive. This would explain how women can start, or be receptive to, a sexual encounter. For example, a woman may enter into sexual activity to increase emotional closeness and commitment without having ...

  15. Healthy Sexuality

    Medline Plus

    Full Text Available ... Links to Professional Societies and Organizations Home › Healthy Sexuality Sexuality is the experience and/or expression of ... is an important part of his or her sexuality. Let’s talk about how a woman’s body responds ...

  16. Healthy Sexuality

    Science.gov (United States)

    ... Links to Professional Societies and Organizations Home › Healthy Sexuality Sexuality is the experience and/or expression of ... is an important part of his or her sexuality. Let’s talk about how a woman’s body responds ...

  17. Healthy Sexuality

    Medline Plus

    Full Text Available ... provider or sexual counselor. Let’s begin with some definitions and explanations. Sexuality is the experience and/or ... affect sexual function include relationship problems, religious beliefs, cultural beliefs, and one’s upbringing. Sex is an important ...

  18. Healthy Sexuality

    Medline Plus

    Full Text Available ... and Smoking Cessation Links to Professional Societies and Organizations Home › Healthy Sexuality Sexuality is the experience and/ ... the course of a lifetime. The World Health Organization has defined sexual health as “…a state of ...

  19. Sexual Problems

    Medline Plus

    Full Text Available ... ways to keep sex special and exciting. Sexual aids include lubricants, moisturizers, and sexual toys. Lubricants work ... a “maintenance therapy” that is applied regularly. Sexual aids, also known as “sex toys” can be used ...

  20. The relationship between overactive bladder and sexual activity in women

    Directory of Open Access Journals (Sweden)

    Patel Ankur S.

    2006-01-01

    Full Text Available PURPOSE: We assessed the relationships between bladder symptoms, demographic, and medical history variables and sexual dysfunction in women with overactive bladder (OAB disorder. MATERIALS AND METHODS: Seventy-eight women diagnosed with OAB completed self-administered questionnaires related to overall heath status, bladder function, and sexual function. Data were compiled for questionnaire responses, and multivariate logistic regression analyses were performed to determine predictors of sexual dysfunction. RESULTS: Bothersome bladder symptoms were reported by superscript three 60% of the sample. Sixty-percent of the sample was sexually active in the past month. Difficulty with sexual arousal, orgasm, and sexual enjoyment were reported by about 25% of the women. Sexual partner status was the best predictor of sexual arousal, orgasm, and sexual enjoyment. Menopausal status emerged as an important predictor of arousal and sexual enjoyment. CONCLUSION: The majority of women with symptoms of OAB viewed these symptoms as bothersome. However, the extent of symptom bother did not predict aspects of female sexual dysfunction (FSD. Instead, menopausal and partner status emerged as the best predictors of FSD in our sample.

  1. Sexual function of women practicing sex in nonconventional settings.

    Science.gov (United States)

    Silveira, Liliam Renata; Romão, Adriana Peterson Mariano Salata; Vieira, Carolina Sales; de Sá Rosa E Silva, Ana Carolina Japur; Reis, Rosana Maria; Ferriani, Rui Alberto; Navarro, Paula Andrea de Albuquerque Salles; Lara, Lúcia Alves da Silva

    2015-01-01

    The quality of sexual intercourse in the context of conjugal visits by women to their jailed partners is unknown. This study aimed to assess the quality of the sex lives and psychological conditions of women attending conjugal visits with their jailed inmate partners. This controlled study involved 124 women between the ages of 18 to 40 years who engaged in sexual relations with their inmate partners (conjugal visit group) or with their partners at home (control group). Sexual function was assessed using a semi-structured questionnaire and the Female Sexual Function Index, and psychological parameters were evaluated using the Hospital Anxiety and Depression scale. The total Female Sexual Function Index scores was similar in the 2 groups. The percentage of women reporting good quality of the relationship was significantly higher in the conjugal visit group. Also, the Hospital Anxiety and Depression scale scores were higher in the conjugal visit group. Depression was a risk factor for sexual dysfunction and had a negative effect on scores in the desire, excitement, lubrication, and sexual satisfaction domains, whereas anxiety was associated with lower sexual desire scores. A regular + poor quality of the relationship and being religious were factors associated with sexual dysfunction. Sexual practices in jail were not a risk for sexual dysfunction in this sample. PMID:24512136

  2. Prevalence of aging male sexual dysfunction in Beijing: the result from a community-based cross-sectional survey of BPC-BPH stndy group%北京市社区中老年男性性功能调查报告:BPC-BPH研究结果

    Institute of Scientific and Technical Information of China (English)

    邵强; 宋健; 孙少鹏; 田野; BPC-BPH研究小组

    2010-01-01

    目的 调查北京市社区中老年男性性欲低下、勃起功能障碍(ED)、射精障碍的患病情况.方法 采用分层多阶段整群不等比例随机抽样方法选择北京市15个社区1656名年龄≥50岁男性作为调查对象,分别记录国际勃起功能问卷(IIEF-5)评分及男性性功能问卷(O'Leary 1995),应用χ~2检验分析结果.结果 符合标准的调查对象共1644人.年龄50~93(64.5±9.8)岁.平均IIEF-5(9.4±8.6)分.以IIEF-5评分0~21诊断为ED,总ED患病率90.45%,性欲低下60.04%,射精障碍38.81%.各年龄组(10岁/组)间ED、性欲低下、射精障碍患病率差异有统计学意义(P<0.0001),各年龄组间不同程度ED患病率差异有统计学意义(P<0.0001).趋势检验表明随年龄增加,ED、性欲低下、射精障碍患病率逐渐增加(Z=10.1,P<0.0001),与年龄呈正相关性.结论 随年龄增加ED、性欲低下、射精障碍的患病率逐渐增加.ED患病率最高.%Objective To investigate the prevalence of aging male sexual dysfunction in Beijing.Methods A cross-sectional study was performed based on community of Beijing in men aged over 50 years old.The International Index of Erectile Function-5(IIEF-5),Brief Male Sexual Function Inventory for Urology(Orleary 1995)were recorded and analyzed.Results 1644 subjects were enrolled and the mean age was 64.5 years(range 50-93 years).The mean score of IIEF-5 was 9.4±8.6.The prevalence of erectile dysfunction(ED),defined as IIEF-5 between 0-21,was 90.45%.The incidence of reduction of sexual desire and defective ejaculation was 60.04%and 38.81%,respectively.There was positive correlation between the prevalence of ED,reduction of sexual desire,defective ejaculation and age.Conclusions The incidence of ED,reduction of sexual desire and defective ejaculation are positively correlated with age.Compared with high prevalence of ED,the incidences of sexual desire and defective ejaculation are lower.

  3. Erectile Dysfunction (ED)

    Science.gov (United States)

    ... age. Is erectile dysfunction just a part of old age? Erectile dysfunction doesn't have to be a ... episode of impotence Feeling stressed, including stress from work or family situations Being troubled by problems in ...

  4. Marriage and Sexuality from a Psychiatric Point of View

    Directory of Open Access Journals (Sweden)

    Ali Bozkurt

    Full Text Available Sexuality, taking on a shape in the interaction of psychological, social, and biological variables, may lose its functionality with the blockage of these components. Sexual dysfunction may be handled as if it is only a symptom being based on the decay of marital relationship in the content of therapy, and sexual dysfunction may be neglected by family and marriage therapists from time to time. Contrarily, sex therapists may show the tendency to handle the problem in aspect of only sexuality. In the relationships of all spouses, thought and emotional intimacy should not be neglected whatever sexual problem they may have. Factors determining happiness such as physical attractiveness, impressiveness, positive and negative attitudes, marriage age, children, socioeconomic conditions, common intentions, and hobbies, sexual life, have attracted the attention of investigators for long time. Most important element among these factors seems to be sexuality. In recent years, researchers have begun to consider interaction between sexuality and marriage much more. Marital life includes food, shelter, togetherness, satisfaction originated from positive marital relationships, sharing role to cause of sexual maturation, acceptance of social role, and responsibility, individual entrepreneurship, and supporting to creativity. Marriage, consisting of spouses completing each other in these fields, is the headstone of social development and maturation. It has been suggested that there is a role of sexual dysfunction in protecting the balance of marital relationships. According to this suggestion, these disorders may prevent any damage to self and conserve the border of ego. Moreover, we may suggest that sexual dysfunction breaks the marital relationship, removes the protective effect on marital balance if we consider the beneficial effects of sexuality in points of intimacy in thought and emotional fields. Sexuality can be only experienced with healthy personality

  5. Primary Orgasmic Dysfunction: Diagnostic Considerations and Review of Treatment

    OpenAIRE

    Andersen, Barbara L.

    1983-01-01

    As a diagnostic category, primary orgasmic dysfunction includes all women who have never experienced orgasm under any circumstances except sleep or fantasy. However, the research samples of nonorgasmic women in clinical reports and empirical investigations are heterogeneous with regard to disruption of earlier phases of the sexual response cycle and emotional concomitants of the dysfunction. The major treatment models—systematic desensitization, sensate focus, directed masturbation, and hypno...

  6. Alga Ecklonia bicyclis, Tribulus terrestris, and Glucosamine Oligosaccharide Improve Erectile Function, Sexual Quality of Life, and Ejaculation Function in Patients with Moderate Mild-Moderate Erectile Dysfunction: A Prospective, Randomized, Placebo-Controlled, Single-Blinded Study

    OpenAIRE

    Salvatore Sansalone; Rosario Leonardi; Gabriele Antonini; Antonio Vitarelli; Giuseppe Vespasiani; Dragoslav Basic; Giuseppe Morgia; Sebastiano Cimino; Giorgio Ivan Russo

    2014-01-01

    We aimed to evaluate the efficacy of oral therapy with alga Ecklonia bicyclis, Tribulus terrestris, and glucosamine oligosaccharide (Tradamix TX1000) in patients with erectile dysfunction (ED) at 3 months of follow-up. From January 2013 to September 2013, 177 patients diagnosed with mild-moderate ED (IIEF-EF < 26) were enrolled in this multicenter, single-blinded, placebo-controlled study and randomized in Group A (Tradamix, n = 87) and Group B (placebo, n = 90). Penile color Doppler ultrasou...

  7. Management of erectile dysfunction.

    Science.gov (United States)

    Heidelbaugh, Joel J

    2010-02-01

    Erectile dysfunction (ED) is the most common sexual problem in men. The incidence increases with age and affects up to one third of men throughout their lives. It causes a substantial negative impact on intimate relationships, quality of life, and self-esteem. History and physical examination are sufficient to make a diagnosis of ED in most cases, because there is no preferred, first-line diagnostic test. Initial diagnostic workup should usually be limited to a fasting serum glucose level and lipid panel, thyroid-stimulating hormone test, and morning total testosterone level. First-line therapy for ED consists of lifestyle changes, modifying drug therapy that may cause ED, and pharmacotherapy with phosphodiesterase type 5 inhibitors. Obesity, sedentary lifestyle, and smoking greatly increase the risk of ED. Phosphodiesterase type 5 inhibitors are the most effective oral drugs for treatment of ED, including ED associated with diabetes mellitus, spinal cord injury, and antidepressants. Intraurethral and intracavernosal alprostadil, vacuum pump devices, and surgically implanted penile prostheses are alternative therapeutic options when phosphodiesterase type 5 inhibitors fail. Testosterone supplementation in men with hypogonadism improves ED and libido, but requires interval monitoring of hemoglobin, serum transaminase, and prostate-specific antigen levels because of an increased risk of prostate adenocarcinoma. Cognitive behavior therapy and therapy aimed at improving relationships may help to improve ED. Screening for cardiovascular risk factors should be considered in men with ED, because symptoms of ED present on average three years earlier than symptoms of coronary artery disease. Men with ED are at increased risk of coronary, cerebrovascular, and peripheral vascular diseases. PMID:20112889

  8. Impact of sexual health course on Malaysian university students.

    Science.gov (United States)

    Low, W Y

    2004-10-01

    A sexual health course was offered and taught by academic staff from the Faculty of Medicine, University of Malaya during semester II of every year as a university elective course to other university students apart from medical students. The course covered a wide range of topics: adolescent sexuality, family planning and pregnancy, violence against women, alternative sexual behavior, physiology of sex, sex and the disabled, gender bias in sexuality, relationship and marriage, sexual dysfunctions, clarification of sexual attitudes and STDs and AIDS. The Sexual Knowledge and Attitude Test (SKAT-II) was used to measure students' pre- and post-course scores on sexual knowledge and attitudes. Fifty-four students who completed both the pre- and post-course tests showed a significant change in sexual knowledge and their attitudes towards sexual myths and autoeroticism. Sexual knowledge was also positively correlated with age, heterosexual relations, autoeroticism and sexual myths scores. However, sexual knowledge is negatively related to religiosity and the influence of religious beliefs on one's attitudes towards sexual matters. This study showed that the sexual health course offered does have a positive impact in increasing one's knowledge and changing one's attitudes towards sexual issues. PMID:15779575

  9. On the interpersonal dynamics of sexuality.

    Science.gov (United States)

    Dewitte, Marieke

    2014-01-01

    To date, theory and research on the interpersonal dynamics of sexuality is scarce. This is remarkable because people most often have sex in a relationship. To create more valid models of sexual functioning, it is important to go beyond the study of individual factors and take into account relational and contextual variables, which may act as risk and protective factors for developing, maintaining, and exacerbating sexual problems. This article describes theoretical ideas on how sexuality and relationships can be linked through motivation and emotion regulation. First, the sexual system is conceptualized as an emotion regulation device that involves a dynamic interplay between cognitive, affective, and motivational responses. Then, it is illustrated how partner variables, relationship processes, and sociorelational context may interact with these different responses and eventually shape how sexual emotions are generated and regulated. The author continues with explaining the implications of such emotion-motivational perspective for studying determinants of sexual responding, the role of coregulation in tuning sexual responses in the couple, and the interrelation between the sexual and relational goals of both partners. Linking sexual and nonsexual aspects of relationships and including data of both couple members is necessary for a clearer insight into the nature of sexual dysfunctions. PMID:24102171

  10. Flibanserin for Treating Hypoactive Sexual Desire Disorder.

    Science.gov (United States)

    Sang, Jae Hong; Kim, Tae-Hee; Kim, Soo Ah

    2016-04-01

    There have been several products developed for male sexual dysfunction. However, developing agents for female sexual dysfunction is lagging behind for various reasons. Sildenafil citrate (Viagra) and Tadalafil (Cialis), which have been prescribed for male sexual function disorders, are known to act on vessels.[1] On the other hand, flibanserin is thought to act on brain. Flibanserin has been approved by U. S. Food and Drug Administration (FDA) for treatment of hypoactive sexual desire disorder (HSDD) of premenopausal women in 2015, and is expected to be released in South Korea soon. Authors wrote this article to acknowledge flibanserin to sexologists for females or physicians for menopausal medicine, so that this agent can be safely used for females who have HSDD. PMID:27152308

  11. How Serious Is Erectile Dysfunction in Men's Lives? Comparative Data From Korean Adults

    OpenAIRE

    Ji, Yoon Seob; Choi, Ji Woong; Ko, Young Hwii; Song, Phil Hyun; Jung, Hee Chang; Moon, Ki Hak

    2013-01-01

    Purpose Whereas sexual function has long been assumed to be an important component of adult men's lives, the impact of sexual dysfunction has not been estimated in parallel to other modern disease entities. We compared the seriousness of erectile dysfunction (ED) with that of other diseases by use of self-administered questionnaires. Materials and Methods Between January 2012 and July 2012, 434 healthy male volunteers (group 1) and 263 ED patients (group 2) were enrolled. The questionnaire co...

  12. Female sexuality.

    Science.gov (United States)

    Rao, T S Sathyanarana; Nagaraj, Anil Kumar M

    2015-07-01

    Sex is a motive force bringing a man and a woman into intimate contact. Sexuality is a central aspect of being human throughout life and encompasses sex, gender identities and roles, sexual orientation, eroticism, pleasure, intimacy, and reproduction. Sexuality is experienced and expressed in thoughts, fantasies, desires, beliefs, attitudes, values, behaviors, practices, roles and relationships. Though generally, women are sexually active during adolescence, they reach their peak orgasmic frequency in their 30 s, and have a constant level of sexual capacity up to the age of 55 with little evidence that aging affects it in later life. Desire, arousal, and orgasm are the three principle stages of the sexual response cycle. Each stage is associated with unique physiological changes. Females are commonly affected by various disorders in relation to this sexual response cycle. The prevalence is generally as high as 35-40%. There are a wide range of etiological factors like age, relationship with a partner, psychiatric and medical disorders, psychotropic and other medication. Counseling to overcome stigma and enhance awareness on sexuality is an essential step in management. There are several effective psychological and pharmacological therapeutic approaches to treat female sexual disorders. This article is a review of female sexuality. PMID:26330647

  13. Female sexuality

    Science.gov (United States)

    Rao, T.S. Sathyanarana; Nagaraj, Anil Kumar M.

    2015-01-01

    Sex is a motive force bringing a man and a woman into intimate contact. Sexuality is a central aspect of being human throughout life and encompasses sex, gender identities and roles, sexual orientation, eroticism, pleasure, intimacy, and reproduction. Sexuality is experienced and expressed in thoughts, fantasies, desires, beliefs, attitudes, values, behaviors, practices, roles and relationships. Though generally, women are sexually active during adolescence, they reach their peak orgasmic frequency in their 30 s, and have a constant level of sexual capacity up to the age of 55 with little evidence that aging affects it in later life. Desire, arousal, and orgasm are the three principle stages of the sexual response cycle. Each stage is associated with unique physiological changes. Females are commonly affected by various disorders in relation to this sexual response cycle. The prevalence is generally as high as 35–40%. There are a wide range of etiological factors like age, relationship with a partner, psychiatric and medical disorders, psychotropic and other medication. Counseling to overcome stigma and enhance awareness on sexuality is an essential step in management. There are several effective psychological and pharmacological therapeutic approaches to treat female sexual disorders. This article is a review of female sexuality. PMID:26330647

  14. 北京地区多中心老年男性性功能障碍危险因素分析%Risk factors of sexual dysfunction in aged men in Beijing : a multicenter community-based cross-sectional survey

    Institute of Scientific and Technical Information of China (English)

    宋健; 邵强; 孙少鹏; 田野; 那彦群; BPC-BPH研究小组

    2012-01-01

    目的 调查北京地区≥50岁男性性功能障碍的患病情况及相关危险因素. 方法 采用分层多阶段整群不等比例随机抽样方法,选择截止到2008年6月1日北京地区15个社区常驻人口中1644例≥50岁男性作为研究对象,记录国际勃起功能问卷(IIEF-5)评分、男性性功能问卷( O'Leary 1995)、IPSS、体质量指数(body mas index,BMI)、前列腺体积,询问既往糖尿病、高血压、高血脂、心脑血管病等史,吸烟和饮酒情况.应用x2检验和Logistic回归法分析与性功能障碍相关的危险因素. 结果 本组勃起功能障碍(ED)、性欲低下和射精障碍的总患病率分别为90.45%、60.04%、38.81%.50 ~59岁、60 ~ 69岁、70 ~ 79岁和≥80岁年龄组间ED、性欲低下和射精障碍的患病率差异有统计学意义(P<0.05);多因素分析结果显示年龄与ED(β =0.12,P<0.05)、性欲低下(β=0.10,P<0.05)和射精障碍(β=0.08,P<0.05)相关,BMI与ED相关(β=0.07,P<0.05),高血压病、前列腺体积是性欲低下(β =0.37,0.08,P<0.05)和射精障碍(β=0.47,0.06,P<0.05)的危险因素;饮酒与射精障碍有关(β=-0.31,P<0.05). 结论 北京地区≥50岁男性ED、性欲低下患病率增加,射精障碍患病率降低,说明中老年男性可以有良好的射精功能,多种因素导致不能达到良好的勃起是影响性生活的主要原因.ED、性欲低下和射精障碍的患病率随年龄增加而增加,年龄是三者共同的危险因素.BMI是ED的危险因素,高血压病、前列腺体积是性欲低下和射精障碍的危险因素;饮酒与射精障碍有关.%Objective To investigate the prevalence of sexual dysfunction in aged men and associated risk factors in Beijing. Methods A cross-sectional study was performed in communities of Beijing involved 1656 men aged over 50 years.The International Index of Erectile Function-5 (IIEF-5),Brief Male Sexual Function Inventory for Urology ( O'Leary 1995 ) and

  15. Sexual and psychological aspects of health status of men who participated in the Chernobyl accident aftermath

    International Nuclear Information System (INIS)

    The paper deals with results of a ten years medical follow-up of 188 men aged 21 to 55 years who participated in liquidation of Chernobyl accident consequences. Survey of patients included physical examination, echography of urogenital organs, semen and prostatic secretions analysis, bacterial inoculation of prostate secretion, hormone studies, sexological questionnaire. Sexual dysfunctions were diagnosed in 38 % of men. It was found that sexual dysfunction occur against the background of neurotic disorders that accompany vegetative dysfunctions.

  16. Sexual Health of Polish Athletes with Disabilities

    Directory of Open Access Journals (Sweden)

    Ryszard Plinta

    2015-06-01

    Full Text Available The purpose of this study was to determine sexual functioning of Polish athletes with disabilities (including paralympians. The study encompassed 218 people with physical disabilities, aged between 18 and 45 (149 men and 69 women. The entire research population was divided into three groups: Polish paralympians (n = 45, athletes with disabilities (n = 126 and non-athletes with disabilities (n = 47. The quality of sexual life of Polish paralympians was measured by using the Polish version of Female Sexual Function Index and International Index of Erectile Function. Clinically significant erectile dysfunctions were most often diagnosed in non-athletes (83.33% with 50% result of severe erectile dysfunctions, followed by athletes and paralympians with comparable results of 56.98% and 54.17% respectively (p = 0.00388. Statistically significant clinical sexual dysfunctions concerned lubrication, orgasm as well as pain domains, and prevailed among female non-athletes (68.42%, 68.42% and 57.89%. Practising sports at the highest level has a favourable effect on the sexuality of men and women with physical disabilities. Men with physical disabilities manifest more sexual disorders than women, an aspect which should be considered by health-care professionals working with people with disabilities.

  17. Perspectives on Sexual Health and Function of Recent Male Combat Veterans of Iraq and Afghanistan

    Directory of Open Access Journals (Sweden)

    Drew A. Helmer, MD, MS

    2015-09-01

    Conclusions: Sexual dysfunction in recent combat veterans can have important negative effects on their health and relationships. Our findings elucidate perceived contributory factors and preferred solutions, which can be applied by health‐care providers to improve the management of sexual dysfunction in these patients. Helmer DA, Beaulieu G, Powers C, Houlette C, Latini D, and Kauth M. Perspectives on sexual health and function of recent male combat veterans of Iraq and Afghanistan. Sex Med 2015;3:137–146.

  18. Medical Help-Seeking for Sexual Concerns in Prostate Cancer Survivors

    OpenAIRE

    Hyde, Melissa K.; Zajdlewicz, Leah; Wootten, Addie C; Nelson, Christian J.; Lowe, Anthony; Dunn, Jeff; Chambers, Suzanne K

    2016-01-01

    Introduction Although sexual dysfunction is common after prostate cancer, men's decisions to seek help for sexual concerns are not well understood. Aim Describe predictors of actual prior help-seeking and intended future medical help-seeking for sexual dysfunction in prostate cancer survivors. Methods A cross-sectional survey of 510 prostate cancer survivors assessed masculine beliefs, attitudes, support/approval from partner/peer networks (subjective norm), and perceived control as predictor...

  19. Management of erectile dysfunction in hypertension:Tips and tricks

    Institute of Scientific and Technical Information of China (English)

    Margus; Viigimaa; Charalambos; Vlachopoulos; Antonios; Lazaridis; Michael; Doumas

    2014-01-01

    Arterial hypertension is a major risk factor for cardiovascular disease and affects approximately one third of the adult population worldwide. The vascular origin of erectile dysfunction is now widely accepted in the vast majority of cases. Erectile dysfunction is frequently encountered in patients with arterial hypertension and greatly affects their quality of life of hypertensive patients and their sexual partners. Therefore, the management of erectile dysfunction in hypertensive patients is of paramount importance. Unfortunately, erectile dysfunction remains under-reported, under-recognized, and under-treated in hypertensive patients, mainly due to the lack of familiarity with this clinical entity by treating physicians. This review aims to discuss the more frequent problems in the management of hypertensive patients with erectile dysfunction and propose ways to overcome these problems in everyday clinical practice.

  20. Risk factors for sexual dysfunction in male patients with obstructive sleep apnea and hypoventilation syndrome%阻塞性睡眠呼吸暂停低通气综合征引起男性性功能障碍危险因素分析

    Institute of Scientific and Technical Information of China (English)

    刘松; 陈颖; 郝钢跃; 贺正一

    2013-01-01

    目的 探讨男性阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者性功能障碍的危险因素.方法 采用国际勃起功能指数量表(IIEF-5)评估121例男性22~50岁OSAHS患者性功能,分为性功能正常组(65例)和性功能障碍组(56例).比较两组患者临床资料和多导睡眠图监测结果.部分性功能障碍患者进行持续气道正压(CPAP)治疗后再次以IIEF-5评价性功能.结果 性功能障碍组患者体质量指数(BMI)显著高于性功能正常组[(31.5±3.9) kg/m2与(30.1±3.5) kg/m2,t=6.897,P<0.01],有糖尿病病史者显著多于性功能正常组(18例与10例,x2=4.750,P<0.05),晨间血压升高者显著多于性功能正常组(38例与27例,x2 =8.381,P<0.01);性功能障碍组患者多导睡眠图监测显示,呼吸紊乱指数(RDI)、最长呼吸暂停时间(Tmax)、最低脉搏血氧饱和度(LSp02)、脉搏血氧饱和度低于90%时间占总睡眠(TST)时间比(T90%)、浅睡眠(S1+S2)占ST比、深睡眠(S3+S4)占TST比、快动眼睡眠(REM)占TST比等指标与性功能正常组之间差异有统计学意义(t值分别为5.290、2.253、3.770、7.536、6.599、3.935和5.536,P均<0.05).多因素Logistic回归分析显示,糖尿病病史、多导睡眠图监测中S1 +S2占TST比、RDI和LSp02对男性OSAHS患者出现性功能障碍有统计学意义,其OR值(95%可信区间)分别为2.10(1.17 ~5.01)、3.52(1.33 ~ 5.97)、1.45(1.08 ~2.95)和0.86(0.67~0.93),P均<0.05.20例性功能障碍患者持续气道正压治疗2个月后14例经IIEF-5评分(>21分)正常.结论 具有糖尿病病史,睡眠结构紊乱S1 +S2占TST比增多、RDI较高和LSpO2较低是男性OSAHS患者发生性功能障碍的独立危险因素.持续气道正压治疗可以显著改善男性OSAHS患者性功能.%Objective To investigate the risk factors of sexual dysfunction in male patients with obstructive sleep apnea and hypoventilation syndrome (OSAHS).Methods One hundred and twenty-one OSAHS male

  1. Sexual function 1-year after allogeneic hematopoietic stem cell transplantation

    DEFF Research Database (Denmark)

    Noerskov, K H; Schjødt, I; Syrjala, K L;

    2016-01-01

    Treatment with allogeneic hematopoietic stem cell transplantation (HSCT) is associated with short and long-term toxicities that can result in alterations in sexual functioning. The aims of this prospective evaluation were to determine: (1) associations between HSCT and increased sexual dysfunction...

  2. Sexuality and breast cancer: prime time for young patients

    Science.gov (United States)

    2013-01-01

    Sexuality and sexual functioning is a cardinal domain of health-related quality of life in breast cancer patients, namely in the younger population. Young women below 40 years of age go through a time in their lives where sexual self-identity has recently matured, their professional obligations are demanding and they bear interpersonal and childbearing expectations, all of which can suffer a devastating turnaround with cancer diagnosis and its physical and psychological aftermath. Although these women’s sexuality and directed interventions have remained largely unaddressed so far, concepts are evolving and treatment options are becoming diversified, chiefly on the field of non-hormonal pharmacological therapy of sexual dysfunction. This review will examine the definitions of female sexual dysfunction, the etiology of the disorders in young breast cancer patients, the assessment methods, the non-pharmacological and pharmacological treatment options and the challenges that lie ahead. PMID:23819031

  3. Internet Sexualities

    Science.gov (United States)

    Döring, Nicola

    The term “internet sexuality” (or OSA, online sexual activities) refers to sexual-related content and activities observable on the internet (cf. Adams, Oye, & Parker, 2003; Cooper, McLoughlin, & Campbell, 2000; Leiblum & Döring, 2002). It designates a variety of sexual phenomena (e.g., pornography, sex education, sexual contacts) related to a wide spectrum of online services and applications (e.g., websites, online chat rooms, peer-to-peer networks). If an even broader range of computer networks - such as the Usenet or bulletin board systems - is included in this extensional definition, one speaks of “online sexuality” or “cybersexuality.”

  4. Sexuality in midlife: Where the passion goes?

    Science.gov (United States)

    Magon, Navneet; Chauhan, Monica; Malik, Sonia; Shah, Duru

    2012-01-01

    Women's sexuality is highly capricious and multifaceted. Sexual functioning is an imperative component of women's lives and has progressively received public health, medical and even pharmaceutical attention. Sexual functioning, however, declines with age, leading to much debate about the contribution of menopause to sexual activity and functioning among women. The past two decades have witnessed an explosion of research into female sexuality. It is now understood that healthy and satisfying sexual function may extend all through the life cycle, and does not finish with end of child bearing years. Very few women's healthcare physicians are adequately trained to monitor a woman's sexual health through her menopausal transition and beyond, much less how to treat the sexual problems that can arise during this special time. The strong association of physical health and psycho-social factors with sexual functioning accentuates the clinical domineering to explore these factors when discussing women's apprehensions regarding sexual dysfunction. It is need of hour to create scientific evidence to help women's health care physicians understand the requirements of women in these special years of her life and help deliver the care they need and so rightly, deserve. PMID:23372319

  5. Erectile dysfunction in haemodialysis patients

    International Nuclear Information System (INIS)

    There is a very high prevalence of Erectile Dysfunction (ED) in dialysis patients. There is no as such available data on ED and factors affecting it in our patients. Analytical, cross-sectional, hospital based study conducted from January to March 2008, Haemodialysis unit of Shalimar and Mayo Hospital, Lahore. All male patients of end stage renal disease (ESRD) on maintenance haemodialysis therapy, whose spouses are alive and able to perform intercourse, were included in the study. Patient with cognitive and communication deficits were excluded from study. International index of erectile function-5 (IIEF-5), adopted in Urdu was used for the determination of prevalence of erectile function. Categorization of erectile dysfunction was done as mild, moderate and severe. Demographic data were collected and certain laboratory parameters (haemoglobin, haematocrit, urea, HBsAg and Anti HCV) were sent. Total numbers of patient were fifty. Major cause of ESRD was diabetes mellitus 28 (56%). Most of the patients 33 (66%) have passed 10th grade or they were under 10th grade. Prevalence of ED was 86% with mean IIEF-5 score of 10.36+-7.13. Majority of patients 33 (64.7%) were suffering from severe degree of ED. Factors responsible for ED are diabetes mellitus, age more than 50 year, high pre dialysis urea and Anti HCV positive patients. In this study, smoking, duration of dialysis and monthly spending is not related with ED. Majority of the patients suffering from ESRD, on maintenance haemodialysis are having ED. None of the patients suffering from ED were taking any treatment for it. Haemodialysis does not improve sexual dysfunction. Major factors responsible for ED are diabetes mellitus, age more than 50 years, high pre dialysis urea and Anti HCV positive patients. (author)

  6. Erectile Dysfunction in Males on Hemodialysis

    International Nuclear Information System (INIS)

    Objective: The determine the frequency of erectile dysfunction in males on hemodialysis. Study Design: Descriptive study. Place and duration: Hemodialysis unit, Combined Military Hospital Kharian from October 2011 to April 2012. Patients and Methods: A total of 150 married male patients of end stage renal disease (ESRD) on hemodialysis were included in the study. Patients with cognitive and/or communication deficits and on hemodialysis for less than 06 months were excluded from the study. Erectile dysfunction (ED) was assessed using International Index of Erectile Function-5 (IIEF-5). Frequency of erectile dysfunction (ED) was analyzed using Statistical Package for Social Sciences (SPSS) version 17. Results: Mean age of the patients were 52.89 = 8.25 years. Mean duration of hemodialysis was 34 +- 9.62 months. The underlying etiology of end stage renal disease were diabetic nephropathy 69(46%), hypertensive nephropathy 51(34%), obstructive nephropathy 18(12%), glomerulonephritis 9(6%), autosomal polycystic kidney disease 3(2%). Mean IIEF-5 score was 13.29 +- 6.38. The frequency of erectile dysfunction was 74%. The majority of the patients, 73(48.7%) had moderate erectile dysfunction, while 24 (16%) had severe and 14 (9.3%) had mild erectile dysfunction. Out of total 150 patients enrolled, 39 (26%) patients had no erectile dysfunction. Conclusion: ED is a highly prevalent problem in men with ESRD. Physicians are urged to recognize the high prevalence of erection problems in men with ESRD and proactively question all patients regarding their sexual function. This will not only improve the recognition of this condition among these patients but also improve the quality of life after adequate treatment. (author)

  7. Understanding and Managing Erectile Dysfunction in Patients Treated for Cancer.

    Science.gov (United States)

    Annam, Kiran; Voznesensky, Maria; Kreder, Karl J

    2016-04-01

    Cancer can cause sexual adverse effects by direct and indirect pathways. It can involve sexual organs, indirectly affect body image, or cause fatigue or depression with subsequent effects on libido. Erectile dysfunction (ED), the inability to obtain or maintain an erection firm enough for sexual intercourse, can also result from adverse effects of cancer treatment, such as fatigue, pain, or anxiety about therapy. In addition, depressed feelings about having cancer can affect sexuality, causing a range of signs and symptoms that can lead to ED. Chemotherapy, hormone therapy, surgery, and radiation can all cause sexual adverse effects. Additional factors that play a role include patient age and degree of ED before starting cancer treatment. In this article, we discuss how chemotherapy, hormone therapy, surgery, and radiation affect erectile function as well as possible treatment options for ED. PMID:27072383

  8. Idade e distúrbios psicológicos: variáveis associadas à disfunção sexual no período pós-infarto Age and psychologic disorders: variables associated to post-infarction sexual dysfunction

    OpenAIRE

    Luciano Janussi Vacanti; Bruno Caramelli

    2005-01-01

    OBJETIVO: As informações sobre a disfunção sexual (DS) após o infarto do miocárdio (IM) são esparsas, principalmente em nosso meio e em relação aos seus preditores. Avaliamos pacientes de ambos os sexos, com vida sexual ativa e sem disfunção sexual prévia ao IM, para estudar a incidência de DS após o IM, e identificar as possíveis variáveis associadas às mesmas. MÉTODOS: Estudamos consecutivamente 43 pacientes, utilizando questionários estruturados para diagnóstico das DS e dos distúrbios psi...

  9. Penisimplantater er en god sidste behandlingsmulighed for erektil dysfunction

    DEFF Research Database (Denmark)

    Giraldi, Laura; Felbo, Jakob; Sønksen, Jens;

    2015-01-01

    When other treatments fail, penile implants represent the last treatment option in erectile dysfunction. The most commonly used implant is the inflatable three-piece device, which allows the penis to be rigid for sexual intercourse and flaccid during the remaining time. Earlier penile implants were...

  10. Nuclear medicine imaging technique in the erectile dysfunction evaluation: a mini-review

    OpenAIRE

    Camila Godinho Ribeiro; Regina Moura; Rosane de Figueiredo Neves; Jean Pierre Spinosa; Mario Bernardo-Filho

    2007-01-01

    Functional imaging with positron emission tomography and single photon emission computed tomography is capable of visualizing subtle changes in physiological function in vivo. Erectile dysfunction(ED) diminishes quality of life for affected men and their partners. Identification of neural substrates may provide information regarding the pathophysiology of types of sexual dysfunction originating in the brain. The aim of this work is to verify the approaches of the nuclear medicine techniques i...

  11. Sexuality and Down Syndrome

    Science.gov (United States)

    ... NDSS Home » Resources » Wellness » Sexuality » Sexuality & Down Syndrome Sexuality & Down Syndrome Human sexuality encompasses an individual's self- ... community standards for adult behavior. How Can Healthy Sexuality be Encouraged for Individuals with Down Syndrome? Creating ...

  12. Erectile dysfunction: management update

    OpenAIRE

    Fazio, Luke; Brock, Gerald

    2004-01-01

    DRAMATIC ADVANCES IN THE MANAGEMENT of erectile dysfunction have occurred over the past decade. Oral therapy with vasoactive agents has emerged as first-line treatment and has transformed both the manner in which the public views erectile dysfunction and the way health care providers deliver care. Whereas an extensive investigation was previously common in the management of erectile dysfunction, recent treatment guidelines promote a more minimalist, goal-oriented approach. In this article, we...

  13. 298例围绝经期女性性功能障碍患病率及患病类型调查%Investigation on the prevalence and the types of female sexual dysfunction(FSD) of 298 cases perimenopause women

    Institute of Scientific and Technical Information of China (English)

    王浅浅; 阮祥燕; 田玄玄; 崔亚美; 杜鹃; Diethelm Wallwiener; Alfred O.Mueck; 代荫梅

    2014-01-01

    Objective To investigate the prevalence and the types of female sexual dysfunction ( FSD) of perimenopause women in our clinic, and the influence of menopause , age, smoking, cohabitation time, the number of pregnancy and depression on female sexual function.Methods This was a cross-sectional study .The patients from Dept .of Gynecological Endocrinology in Beijing Obstetrics and Gynecology Hospital affiliated to Capital Medical University and menopausal women from different communities of Heilongjiang and Shandong Province were investigated with questionnaires of FSFI and self rating Depression Scale ( SDS) .All data were analyzed by SPSS 13.0.Results A total of 500 questionnaires were granted and 92.2% of those were recovered .298 questionnaires were included for analysis after screening in the end .The average total score of FSFI was 23.69 and the prevalence of FSD is 58.1% in perimenopause women according to the definition of FSD , the total score of FSFI below of 26.55, in our study.According to the 6 dimensions of FSFI , the prevalence of sexual desire disorder , sexual arousal disorder , orgasm disorder , sexual satisfaction disorder , sexual pain and vaginal lubrication disorders were 50.7%, 43.3%, 35.6%, 33.6%, 29.5%and 28.5%orderly.Higher age and depression are risks for FSD (P0.05).Conclusion The prevalence of FSD of perimenopause women in our clinic is 58.1%, and the prevalence of sexual desire disorder , sexual arousal disorder , orgasm disorder , sexual satisfaction disorder , sexual pain and vaginal lubrication disorders were 50.7%, 43.3%, 35.6%, 33.6%, 29.5%and 28.5%in turn.%目的:调查中国围绝经期女性性功能障碍的患病率和患病类型,以及绝经、年龄、抑郁心理、与性伴侣同居时间、吸烟、妊娠次数等因素对女性性功能的影响。方法采用横断面研究方法,应用女性性功能量表( Female Sexual Function Index ,FSFI)、抑郁自评量表( Self Rating Depression Scale ,SDS)

  14. Investigation on the prevalence and the types of female sexual dysfunction(FSD) of 298 cases perimenopause women%298例围绝经期女性性功能障碍患病率及患病类型调查

    Institute of Scientific and Technical Information of China (English)

    王浅浅; 阮祥燕; 田玄玄; 崔亚美; 杜鹃; Diethelm Wallwiener; Alfred O.Mueck; 代荫梅

    2014-01-01

    Objective To investigate the prevalence and the types of female sexual dysfunction ( FSD) of perimenopause women in our clinic, and the influence of menopause , age, smoking, cohabitation time, the number of pregnancy and depression on female sexual function.Methods This was a cross-sectional study .The patients from Dept .of Gynecological Endocrinology in Beijing Obstetrics and Gynecology Hospital affiliated to Capital Medical University and menopausal women from different communities of Heilongjiang and Shandong Province were investigated with questionnaires of FSFI and self rating Depression Scale ( SDS) .All data were analyzed by SPSS 13.0.Results A total of 500 questionnaires were granted and 92.2% of those were recovered .298 questionnaires were included for analysis after screening in the end .The average total score of FSFI was 23.69 and the prevalence of FSD is 58.1% in perimenopause women according to the definition of FSD , the total score of FSFI below of 26.55, in our study.According to the 6 dimensions of FSFI , the prevalence of sexual desire disorder , sexual arousal disorder , orgasm disorder , sexual satisfaction disorder , sexual pain and vaginal lubrication disorders were 50.7%, 43.3%, 35.6%, 33.6%, 29.5%and 28.5%orderly.Higher age and depression are risks for FSD (P0.05).Conclusion The prevalence of FSD of perimenopause women in our clinic is 58.1%, and the prevalence of sexual desire disorder , sexual arousal disorder , orgasm disorder , sexual satisfaction disorder , sexual pain and vaginal lubrication disorders were 50.7%, 43.3%, 35.6%, 33.6%, 29.5%and 28.5%in turn.%目的:调查中国围绝经期女性性功能障碍的患病率和患病类型,以及绝经、年龄、抑郁心理、与性伴侣同居时间、吸烟、妊娠次数等因素对女性性功能的影响。方法采用横断面研究方法,应用女性性功能量表( Female Sexual Function Index ,FSFI)、抑郁自评量表( Self Rating Depression Scale ,SDS)

  15. Healthy Sexuality

    Medline Plus

    Full Text Available ... or other), gender roles (a person’s expression of social and behavioral norms), and sexual orientation (who a ... as “…a state of physical, emotional, mental and social well-being in relation to sexuality; it is ...

  16. Healthy Sexuality

    Medline Plus

    Full Text Available ... Smoking Cessation Links to Professional Societies and Organizations Home › Healthy Sexuality Sexuality is the experience and/or ... Find a Health Care Provider Back to Top Home | About Us | Reproductive Health Topics | News & Publications | Resources ...

  17. Healthy Sexuality

    Medline Plus

    Full Text Available ... body responds to sexual stimulation. During sexual arousal, blood flow increases to a woman’s genitals. Her vagina ... changes occur; a woman’s nipples become erect, her blood pressure and heart rate increase, and a “sex ...

  18. Sexual Problems

    Medline Plus

    Full Text Available ... with your sexual partner. Because they are complex, sexual concerns are treated in many different ways. Often, multiple types of treatment may be required and are used together to treat a problem. Education is important in understanding the anatomy and physiology ...

  19. Sexual revolutions

    NARCIS (Netherlands)

    G. Hekma; A. Giami

    2014-01-01

    The sexual revolution of 1960-1980 created a major break in attitudes and practices in Western societies. It created many new freedoms for gay men, youth and women, in terms of sexual imagery, information, and rights. Leftists denounced the revolution's consumerism whilst feminists lamented its cont

  20. Healthy Sexuality

    Medline Plus

    Full Text Available ... defined sexual health as “…a state of physical, emotional, mental and social well-being in relation to ... a women’s response intertwines both her physical and emotional sexual drive. This would explain how women can ...

  1. Sexual Problems

    Medline Plus

    Full Text Available ... important to note that psychological problems such as sexual abuse can be involved as well. Pain caused by lack of lubrication or by vaginismus is not included in this ... woman wants sexual penetration. Women with this condition can still achieve ...

  2. Sexual Problems

    Medline Plus

    Full Text Available ... sexual setting by enhancing communication with your partner, promoting non-sexual intimacy, and finding ways to keep ... focuses on how one’s thinking influences feelings and behavior. Sensate focus exercises are structured “touching” activities that ...

  3. Healthy Sexuality

    Medline Plus

    Full Text Available ... to sexual stimulation. During sexual arousal, blood flow increases to a woman’s genitals. Her vagina is lubricated ... become erect, her blood pressure and heart rate increase, and a “sex flush” from the stomach to ...

  4. Healthy Sexuality

    Medline Plus

    Full Text Available ... esteem, and cardiovascular health. A person’s physical sexual response is an important part of his or her ... There are also physical changes during the sexual response in men. During arousal, a man’s penis becomes ...

  5. Healthy Sexuality

    Medline Plus

    Full Text Available ... important issues for many people, regardless of their age, sex, or gender. Although many people are embarrassed or afraid to talk about sex or sexuality, it’s important to bring up any concerns with your healthcare provider or sexual counselor. Let’s begin with some ...

  6. Sexual Abuse

    Science.gov (United States)

    Navigation Physical Abuse Sexual Abuse Domestic Violence Psychological Abuse Financial Abuse Neglect Critical Issues What Communities Can Do The Role ... Abuse and Neglect Ramsey-Klawsnik, H. (1996). Assessing physical and sexual abuse in health care settings. In L.A. Baumhover & S. ...

  7. Brief Emotion Regulation Training Facilitates Arousal Control During Sexual Stimuli.

    Science.gov (United States)

    van Overveld, Mark; Borg, Charmaine

    2015-01-01

    Disgust, a negative emotion which evokes strong behavioral avoidance tendencies, has been associated with sexual dysfunction. Recently, it was postulated that healthy sexual functioning requires a balance between excitatory (increased sexual arousal) and inhibitory processes (lowered disgust levels). This suggests that amplification of excitatory processes (like sexual arousal) could be a valuable addition to treatments for affect-based sexual dysfunctions. The major aim of the present study was to establish whether up-regulation could effectively enhance arousal levels during sexual stimuli, and whether such a training would simultaneously reduce disgust. Students (N = 163, mean age = 20.73 years, SD = 2.35) were trained in up-regulation of affect using either a sexual arousal film (i.e., female-friendly erotic movie) or a threat arousal film clip (i.e., horror movie), while control groups viewed the films without training instructions. Following this, participants viewed and rated state emotions during a series of pictures (sexual, disgusting, or neutral). Up-regulation of mood successfully enhanced general arousal in both groups, yet these arousal levels were not paralleled by reductions in disgust. Overall, the findings indicate that emotion regulation training by maximizing positive affect and general arousal could be an effective instrument to facilitate affect-related disturbances in sexual dysfunctions. PMID:25258109

  8. Penile prosthesis implant for erectile dysfunction: A new minimally invasive infrapubic surgical technique

    OpenAIRE

    Gabriele Antonini; Gian Maria Busetto; Ettore De Berardinis; Riccardo Giovannone; Patrizio Vicini; Vincenzo Gentile; Paul E. Perito

    2016-01-01

    Erectile dysfunction, the most common male sexual disorder after premature ejaculation, with its important impact on man and partner’s sexuality and quality of life is a persistent inability to obtain and maintain an erection sufficient to permit satisfactory sexual performance. Non-surgical treatments with controversial results are usually applyed before surgical treatment that has reached high levels of satisfaction. We describe a new surgical technique to implant three-pieces penile prosth...

  9. Psychophysiological Reactivity in Child Sexual Abuse.

    Science.gov (United States)

    Ben-Amitay, Galit; Kimchi, Nir; Wolmer, Leo; Toren, Paz

    2016-01-01

    Sexual abuse has physiological and emotional implications. The purpose of this study is to evaluate the neurobiological sequels of childhood sexual trauma by monitoring physiological variables among sexually abused girls and women compared to controls. We assessed posttrauma and traumatic life events of 35 females sexually abused in their childhood (age range 7-51 years) and 25 control females (age range 7-54 years). Electroencephalography, frontalis electromyography, electrodermal activity, and heart rate parameters were recorded while watching sets of pictures representing neutral and trauma-suggestive stimuli. A minority of participants met the Diagnostic and Statistical Manual of Mental Disorders criteria for post-traumatic stress disorder. Abused females displayed significant elevations in heart rate, electromyography, and electroencephalography while viewing allusive stimuli and elevated heart rate while viewing neutral stimuli. The dysfunctional regulation of the physiological stress system associated with child sexual abuse may endanger the victims with various stress and anxiety disorders. PMID:26934544

  10. Sexual concerns and practices after ICD implantation

    DEFF Research Database (Denmark)

    Berg, Selina Kikkenborg; Elleman-Jensen, Line; Zwisler, Ann-Dorthe;

    2013-01-01

    Background:Studies show that patients with implantable cardioverter defibrillators (ICD) frequently experience sexual dysfunction. These experiences are often linked to exercise intolerance, side-effects of medication, and psychological problems.Objective:To describe (a) the level of information...... given about sexual activity, (b) the areas of patient concerns related to sexual function and the ICD, and (c) changes in sexual behavior.Methods:A randomized controlled trial including 196 patients (1:1) was designed, including 12 weeks of exercise training and 1 year of psycho-educational follow......-up focusing on modifiable factors associated with poor outcomes, including sexual functioning. The Sex After ICD Survey was administered 6 months after the randomization as part of the planned explorative outcomes. 141 patients responded.Results:The analyses showed that 37 of the 69 (55.2%) patients of the...

  11. Efeitos colaterais dos psicofármacos na esfera sexual Sexual side effects of psychotropic drugs

    Directory of Open Access Journals (Sweden)

    Táki Athanássios Cordás

    2006-01-01

    Full Text Available Disfunções sexuais são altamente prevalentes em mulheres e relacionadas, entre outros fatores, a estados afetivos, aspectos socioculturais, situações interpessoais e psicofármacos. As disfunções sexuais induzidas por psicofármacos são brevemente revistas.Sexual dysfunctions are highly prevalent in women and are affected by, among other factors, affective states, sociocultural aspects, interpersonal situations and psychotropic medications. The sexual dysfunction induced by psychotropic medications was briefly reviewed.

  12. Sexuality in men after prostate cancer surgery

    DEFF Research Database (Denmark)

    Schantz Laursen, Birgitte

    2016-01-01

    INTRODUCTION: Prostate cancer affects a growing number of men. Although erectile dysfunction is a well-known side effect, its impact on sex life and sexuality is under-researched. PURPOSE: The aim of this study was therefore to elucidate the effect of surgical treatment for prostate cancer on men...

  13. Possible ways of correction and treatment of sexual disturbances at men-liquidators of accident on Chernobyl NPP. Chapter 12

    International Nuclear Information System (INIS)

    Main aspects of sexual dysfunction treatment are discussed in the chapter. It is noted that the individual comprehensive system approach to treatment is necessary. In treatment of sexual dysfunctions it is important take into account all components of disease (neuro gumoral, mental etc)

  14. Erectile dysfunction as a manifestation of urogenital autonomic neuropathy in patients with type 1 diabetes: epidemiology, classification, pathophysiology, diagnosis and treatment options

    Directory of Open Access Journals (Sweden)

    Gagik Radikovich Galstyan

    2014-05-01

    Full Text Available Sexual dysfunction characterized by a significant decline in the quality of life of patients and leading to infertility and problems in social life is diagnosed in more than 40% of patients with diabetes mellitus (DM.Erectile dysfunction is the most common sexual disorder in DM patients. The article describes epidemiology, classification, pathophysiology, diagnostic and treatment of erectile dysfunction in T1DM patients.

  15. Sibling Sexual Abuse: An Empirical Analysis of Offender, Victim, and Event Characteristics in National Incident-Based Reporting System (NIBRS) Data, 2000-2007

    Science.gov (United States)

    Krienert, Jessie L.; Walsh, Jeffrey A.

    2011-01-01

    Sibling sexual abuse is identified as the most common form of familial sexual abuse. Extant literature is plagued by definitional inconsistencies, data limitations, and inadequate research methodology. Trivialized as "normal" sexual exploration, sibling sexual abuse has been linked to psychosocial/psychosexual dysfunction. Research has relied on…

  16. Sexual Problems

    Medline Plus

    Full Text Available ... with several side effects. Phosphodiesterase inhibitors such as sildenafil, vardenafil, and tadalafil, are approved for treatment of erectile dysfunction in men. Women who were given sildenafil in studies also had increased blood flow to ...

  17. 疏肝益阳胶囊对动脉性勃起功能障碍大鼠性功能及性腺质量的作用%Effect of Shuganyiyang Capsules on Sexual Function and Sex Gland Weight in Rats with Arteriogenic Erectile Dysfunction

    Institute of Scientific and Technical Information of China (English)

    王济; 白明华; 刘保兴; 杨寅; 杨玲玲; 王琦

    2013-01-01

    目的 观察中药疏肝益阳胶囊对动脉性勃起功能障碍(arteriogenic erectile dysfunction,AED)模型大鼠性功能及睾丸和附属性腺器官质量的改善作用.方法 选取3月龄成年雄性SD大鼠50只,采用双侧髂内动脉结扎法复制AED模型.设假手术组、模型组、西地那非组(每日10.5 mg/kg)、疏肝益阳胶囊大剂量组(每日1 g/kg)、疏肝益阳胶囊小剂量组(每日0.5 g/kg),每组10只,灌胃给药,疗程30 d.行阿朴吗啡(apomorphine,APO)试验检测性功能,取双侧睾丸及附睾、前列腺、精囊腺、球海绵体肌,称湿质量并计算质量系数.结果 APO试验显示疏肝益阳胶囊大、小剂量可显著增加AED大鼠30 min内阴茎勃起次数(P<0.01).疏肝益阳胶囊大、小剂量可显著增加AED大鼠睾丸、附睾、球海绵体肌质量系数(P<0.05).结论 疏肝益阳胶囊可明显改善AED大鼠的性功能,并可使睾丸及其附属性器官质量系数显著增加.%Objective To observe the effect of Shuganyiyang (SGYY) Capsules (for dispersing stagnated liver qi and nourishing yang) on the sexual function and the weights of testes and accessory sex glands in rats with arteriogenic erectile dysfunction (AED). Methods Fifty male Sprague-Dawley rats aged 3 months were selected in the study. Bilateral internal iliac artery ligation was used to induce a rat model of AED. The rats were randomly and equally divided into sham operation group, model group, sidenafil (10. 5 mg/kg daily) group, high-dose SGYY Capsule (1 g/kg daily) group, and low-dose SGYY Capsule (0. 5 g/kg daily) group and received their respective treatments by intragastric administration for 30 d. The sexual function of rats in each group was evaluated by apomorphine (APO) test. The bilateral testes and epididymides, prostate, seminal vesicle, and bulbocavernosus muscle of rats were collected; the wet weight of each organ was measured, and the weight coefficient was calculated. Results The APO test showed that

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