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Sample records for anti de sitter group

  1. Noncommutative Relativistic Spacetimes and Worldlines from 2 + 1 Quantum (Anti-de Sitter Groups

    Directory of Open Access Journals (Sweden)

    Ángel Ballesteros

    2017-01-01

    Full Text Available The κ-deformation of the (2 + 1D anti-de Sitter, Poincaré, and de Sitter groups is presented through a unified approach in which the curvature of the spacetime (or the cosmological constant is considered as an explicit parameter. The Drinfel’d-double and the Poisson–Lie structure underlying the κ-deformation are explicitly given, and the three quantum kinematical groups are obtained as quantizations of such Poisson–Lie algebras. As a consequence, the noncommutative (2 + 1D spacetimes that generalize the κ-Minkowski space to the (anti-de Sitter ones are obtained. Moreover, noncommutative 4D spaces of (time-like geodesics can be defined, and they can be interpreted as a novel possibility to introduce noncommutative worldlines. Furthermore, quantum (anti-de Sitter algebras are presented both in the known basis related to 2 + 1 quantum gravity and in a new one which generalizes the bicrossproduct one. In this framework, the quantum deformation parameter is related to the Planck length, and the existence of a kind of “duality” between the cosmological constant and the Planck scale is also envisaged.

  2. Quantum groups, roots of unity and particles on quantized Anti-de Sitter space

    Energy Technology Data Exchange (ETDEWEB)

    Steinacker, Harold [Univ. of California, Berkeley, CA (United States). Dept. of Physics

    1997-05-23

    Quantum groups in general and the quantum Anti-de Sitter group Uq(so(2,3)) in particular are studied from the point of view of quantum field theory. The author shows that if q is a suitable root of unity, there exist finite-dimensional, unitary representations corresponding to essentially all the classical one-particle representations with (half) integer spin, with the same structure at low energies as in the classical case. In the massless case for spin ≥ 1, "naive" representations are unitarizable only after factoring out a subspace of "pure gauges", as classically. Unitary many-particle representations are defined, with the correct classical limit. Furthermore, the author identifies a remarkable element Q in the center of Uq(g), which plays the role of a BRST operator in the case of Uq(so(2,3)) at roots of unity, for any spin ≥ 1. The associated ghosts are an intrinsic part of the indecomposable representations. The author shows how to define an involution on algebras of creation and anihilation operators at roots of unity, in an example corresponding to non-identical particles. It is shown how nonabelian gauge fields appear naturally in this framework, without having to define connections on fiber bundles. Integration on Quantum Euclidean space and sphere and on Anti-de Sitter space is studied as well. The author gives a conjecture how Q can be used in general to analyze the structure of indecomposable representations, and to define a new, completely reducible associative (tensor) product of representations at roots of unity, which generalizes the standard "truncated" tensor product as well as many-particle representations.

  3. Radial dimensional reduction: (anti) de Sitter theories from flat

    Science.gov (United States)

    Biswas, Tirthabir; Siegel, Warren

    2002-07-01

    We propose a new form of dimensional reduction that constrains dilatation instead of a component of momentum. It corresponds to replacing toroidal compactification in a cartesian coordinate with that in the logarithm of the radius. Massive theories in de Sitter or anti de Sitter space are thus produced from massless (scale invariant) theories in one higher space or time dimension. As an example, we derive free massive actions for arbitrary representations of the (anti) de Sitter group in arbitrary dimensions. (Previous general results were restricted to symmetric tensors.) We also discuss generalizations to interacting theories.

  4. Remarks on quantum field theory on de Sitter and anti-de Sitter ...

    Indian Academy of Sciences (India)

    2012-06-14

    Jun 14, 2012 ... Quantum field theory on de Sitter and anti-de Sitter space-times the permuted extended tuboids contains all the non-coinciding points of the 'Euclidean' de Sitter world, i.e.. {(z1,..., zn) ∈ Sn d : zj = zk. ∀ j = k}. (3.19). 3.4 Perturbation theory. Perturbation theory can be set up in de Sitter space-time, as it is a ...

  5. Group averaging for de Sitter free fields

    Energy Technology Data Exchange (ETDEWEB)

    Marolf, Donald; Morrison, Ian A, E-mail: marolf@physics.ucsb.ed, E-mail: ian_morrison@physics.ucsb.ed [Department of Physics, University of California, Santa Barbara, CA 93106 (United States)

    2009-12-07

    Perturbative gravity about global de Sitter space is subject to linearization-stability constraints. Such constraints imply that quantum states of matter fields couple consistently to gravity only if the matter state has vanishing de Sitter charges, i.e. only if the state is invariant under the symmetries of de Sitter space. As noted by Higuchi, the usual Fock spaces for matter fields contain no de Sitter-invariant states except the vacuum, though a new Hilbert space of de Sitter-invariant states can be constructed via so-called group-averaging techniques. We study this construction for free scalar fields of arbitrary positive mass in any dimension, and for linear vector and tensor gauge fields in any dimension. Our main result is to show in each case that group averaging converges for states containing a sufficient number of particles. We consider general N-particle states with smooth wavefunctions, though we obtain somewhat stronger results when the wavefunctions are finite linear combinations of de Sitter harmonics. Along the way we obtain explicit expressions for general boost matrix elements in a familiar basis.

  6. Remarks on quantum field theory on de Sitter and anti-de Sitter ...

    Indian Academy of Sciences (India)

    2012-06-14

    Jun 14, 2012 ... The literature devoted to quantum field theory (QFT) on the de Sitter and anti-de Sitter space-times is enormous. This short review is limited to work done in recent years with the authors quoted in the abstract. The most significant results described here are the two explicit Källén–Lehmann representations ...

  7. Consistent higher derivative gravitational theories with stable de Sitter and anti-de Sitter backgrounds

    NARCIS (Netherlands)

    Biswas, Tirthabir; Koshelev, Alexey S.; Mazumdar, Anupam

    2017-01-01

    In this paper we provide the criteria for any generally covariant, parity preserving, and torsion-free theory of gravity to possess a stable de Sitter (dS) or anti-de Sitter (AdS) background. By stability we mean the absence of tachyonic or ghostlike states in the perturbative spectrum that can lead

  8. Mass in anti-de Sitter spaces

    International Nuclear Information System (INIS)

    Liu, James T.; Sabra, W.A.

    2005-01-01

    The boundary stress tensor approach has proven extremely useful in defining mass and angular momentum in asymptotically anti-de Sitter spaces with CFT duals. An integral part of this method is the use of boundary counterterms to regulate the gravitational action and stress tensor. In the presence of matter, however, ambiguities may arise that are related to the addition of possible finite counterterms. We demonstrate this explicitly for R-charged black holes in AdS 5 , where introduction of a finite counterterm proportional to φ 2 is necessary to properly reproduce the expected mass/charge relation for the black holes

  9. Superfield approach to anti de Sitter supersymmetry

    International Nuclear Information System (INIS)

    Ivanov, E.A.

    1979-01-01

    A self-contained superfield approach to global supersymmetry in anti de Sitter space (OSp(1.4)) is developed. General transformation laws for OSp(1.4)-superfields are established, and all basic elements of the OSp(1.4)-covariant formalism in the real basis, such as covariant superfield derivatives, invariant integration measure over the superspace OSp(1.4)/O(1.3), etc., are explicitly given. The reducibility questions are analyzed and realizations of OSp(1.4) in the left- and right-handed chiral superspaces are found

  10. Analytical Solutions of the Gravitational Field Equations in de Sitter and Anti-de Sitter Spacetimes

    Science.gov (United States)

    Da Rocha, R.; Capelas Oliveira, E.

    2009-01-01

    The generalized Laplace partial differential equation, describing gravitational fields, is investigated in de Sitter spacetime from several metric approaches—such as the Riemann, Beltrami, Börner-Dürr, and Prasad metrics—and analytical solutions of the derived Riccati radial differential equations are explicitly obtained. All angular differential equations trivially have solutions given by the spherical harmonics and all radial differential equations can be written as Riccati ordinary differential equations, which analytical solutions involve hypergeometric and Bessel functions. In particular, the radial differential equations predict the behavior of the gravitational field in de Sitter and anti-de Sitter spacetimes, and can shed new light on the investigations of quasinormal modes of perturbations of electromagnetic and gravitational fields in black hole neighborhood. The discussion concerning the geometry of de Sitter and anti-de Sitter spacetimes is not complete without mentioning how the wave equation behaves on such a background. It will prove convenient to begin with a discussion of the Laplace equation on hyperbolic space, partly since this is of interest in itself and also because the wave equation can be investigated by means of an analytic continuation from the hyperbolic space. We also solve the Laplace equation associated to the Prasad metric. After introducing the so called internal and external spaces—corresponding to the symmetry groups SO(3,2) and SO(4,1) respectively—we show that both radial differential equations can be led to Riccati ordinary differential equations, which solutions are given in terms of associated Legendre functions. For the Prasad metric with the radius of the universe independent of the parametrization, the internal and external metrics are shown to be of AdS-Schwarzschild-like type, and also the radial field equations arising are shown to be equivalent to Riccati equations whose solutions can be written in terms of

  11. Localized Gravity on Branes in anti-de Sitter Spaces

    OpenAIRE

    Halyo, Edi

    1999-01-01

    We discuss the conditions under which 4D gravity is localized on domain walls in 5D anti-de Sitter spaces. Our approach is based on considering the limits in which the localized gravity decouples. We find that gravity is localized if the wall is located a finite distance from the boundary of the anti-de Sitter space and has a finite tension. In addition, it has to be a $\\delta$-function source of gravity.

  12. Quantum fields in anti-de Sitter wormholes

    OpenAIRE

    Barcelo, Carlos; Garay, Luis J.

    1997-01-01

    We study the effects of asymptotically anti-de Sitter wormholes in low-energy field theory and give a general prescription for obtaining the local effective interaction terms induced by them. The choice of vacuum for the matter fields selects a basis of the Hilbert space of anti-de Sitter wormholes whose elements can be interpreted as states containing a given number of particles. This interpretation is subject to the same kind of ambiguity in the definition of a particle as that arising from...

  13. Difference between anti-de Sitter and de Sitter spaces: wave equation approach

    International Nuclear Information System (INIS)

    Myung, Y S; Kim, N J

    2004-01-01

    We study the wave equation for a massive scalar field in three-dimensional anti-de Sitter (AdS) black hole and de Sitter (dS) spaces to find what are the differences and similarities between the two spaces. Here the AdS black hole is provided by the J = 0 BTZ black hole. To investigate its event (cosmological) horizons, we compute the absorption cross section, quasinormal modes and study the AdS(dS)/CFT correspondences. Although there remains an unclear point in defining the ingoing flux near infinity of the BTZ black hole, quasi-normal modes are obtained and the AdS/CFT correspondence is confirmed. However, we do not find quasi-normal modes and thus do not confirm the assumed dS/CFT correspondence. This difference between AdS black hole and dS spaces is very interesting, because their global structures are similar to each other

  14. Covariant fields on anti-de Sitter spacetimes

    Science.gov (United States)

    Cotăescu, Ion I.

    2018-02-01

    The covariant free fields of any spin on anti-de Sitter (AdS) spacetimes are studied, pointing out that these transform under isometries according to covariant representations (CRs) of the AdS isometry group, induced by those of the Lorentz group. Applying the method of ladder operators, it is shown that the CRs with unique spin are equivalent with discrete unitary irreducible representations (UIRs) of positive energy of the universal covering group of the isometry one. The action of the Casimir operators is studied finding how the weights of these representations (reps.) may depend on the mass and spin of the covariant field. The conclusion is that on AdS spacetime, one cannot formulate a universal mass condition as in special relativity.

  15. Penrose inequality in anti-de Sitter space

    Science.gov (United States)

    Husain, Viqar; Singh, Suprit

    2017-11-01

    For asymptotically flat spacetimes the Penrose inequality gives an initial data test for the weak cosmic censorship hypothesis. We give a formulation of this inequality for asymptotically anti-de Sitter (AAdS) spacetimes, and show that the inequality holds for time asymmetric data in spherical symmetry. Our analysis is motivated by the constant-negative-spatial-curvature form of the AdS black hole metric.

  16. On electric field in anti-de Sitter spacetime

    Energy Technology Data Exchange (ETDEWEB)

    Cheong, Lee Yen, E-mail: lee-yencheong@petronas.com.my, E-mail: chewxy01813@gmail.com, E-mail: dennis.ling@petronas.com.my; Yan, Chew Xiao, E-mail: lee-yencheong@petronas.com.my, E-mail: chewxy01813@gmail.com, E-mail: dennis.ling@petronas.com.my; Ching, Dennis Ling Chuan, E-mail: lee-yencheong@petronas.com.my, E-mail: chewxy01813@gmail.com, E-mail: dennis.ling@petronas.com.my [Department of Fundamental and Applied Sciences, Universiti Teknologi Petronas, Bandar Seri Iskandar, Tronoh 31750, Perak (Malaysia)

    2014-10-24

    In this paper we calculate the electromagnetic field produced using retarded Green's function in Anti-de Sitter spacetime (AdS). Since this spacetime is non-globally hyperbolic and has no Cauchy surface, we only consider the field originated from a charge moving along its geodesic in the region consists of points covered by future null geodesic of the charge.

  17. Discrete Torsion, (Anti) de Sitter D4-Brane and Tunneling

    Science.gov (United States)

    Singh, Abhishek K.; Pandey, P. K.; Singh, Sunita; Kar, Supriya

    2014-06-01

    We obtain quantum geometries on a vacuum created pair of a (DDbar)3-brane, at a Big Bang singularity, by a local two form on a D4-brane. In fact our analysis is provoked by an established phenomenon leading to a pair creation by a gauge field at a black hole horizon by Stephen Hawking in 1975. Importantly, the five dimensional microscopic black holes are described by an effective non-perturbative curvature underlying a discrete torsion in a second order formalism. In the case for a non-propagating torsion, the effective curvature reduces to Riemannian, which in a low energy limit may describe Einstein vacuum in the formalism. In particular, our analysis suggests that a non-trivial space begin with a hot de Sitter brane-Universe underlying a nucleation of a vacuum pair of (DDbar)-instanton at a Big Bang. A pair of instanton nucleats a D-particle which in turn combines with an anti D-particle to describe a D-string and so on. The nucleation of a pair of higher dimensional pair of brane/anti-brane from a lower dimensional pair may be viewed via an expansion of the brane-Universe upon time. It is in conformity with the conjecture of a branes within a brane presumably in presence of the non-zero modes of two form. Interestingly, we perform a thermal analysis underlying various emergent quantum de Sitter vacua on a D4-brane and argue for the plausible tunneling geometries underlying a thermal equilibrium. It is argued that a de Sitter Schwarzschild undergoes quantum tunneling to an AdS-brane Schwarzschild via Nariai and de Sitter topological black hole.

  18. Discrete Torsion, (Anti) de Sitter D4-Brane and Tunneling

    International Nuclear Information System (INIS)

    Singh, Abhishek K.; Pandey, P.K.; Singh, Sunita; Kar, Supriya

    2014-01-01

    We obtain quantum geometries on a vacuum created pair of a (DD ¯ ) 3 -brane, at a Big Bang singularity, by a local two form on a D 4 -brane. In fact our analysis is provoked by an established phenomenon leading to a pair creation by a gauge field at a black hole horizon by Stephen Hawking in 1975. Importantly, the five dimensional microscopic black holes are described by an effective non-perturbative curvature underlying a discrete torsion in a second order formalism. In the case for a non-propagating torsion, the effective curvature reduces to Riemannian, which in a low energy limit may describe Einstein vacuum in the formalism. In particular, our analysis suggests that a non-trivial space begin with a hot de Sitter brane-Universe underlying a nucleation of a vacuum pair of (DD ¯ )-instanton at a Big Bang. A pair of instanton nucleats a D-particle which in turn combines with an anti D-particle to describe a D-string and so on. The nucleation of a pair of higher dimensional pair of brane/anti-brane from a lower dimensional pair may be viewed via an expansion of the brane-Universe upon time. It is in conformity with the conjecture of a branes within a brane presumably in presence of the non-zero modes of two form. Interestingly, we perform a thermal analysis underlying various emergent quantum de Sitter vacua on a D 4 -brane and argue for the plausible tunneling geometries underlying a thermal equilibrium. It is argued that a de Sitter Schwarzschild undergoes quantum tunneling to an AdS-brane Schwarzschild via Nariai and de Sitter topological black hole

  19. Instability of charged anti-de Sitter black holes

    International Nuclear Information System (INIS)

    Gwak, Bogeun; Lee, Bum-Hoon; Ro, Daeho

    2016-01-01

    We have studied the instability of charged anti-de Sitter black holes in four- or higher-dimensions under fragmentation. The unstable black holes under fragmentation can be broken into two black holes. Instability depends not only on the mass and charge of the black hole but also on the ratio between the fragmented black hole and its predecessor. We have found that the near extremal black holes are unstable, and Schwarzschild-AdS black holes are stable. These are qualitatively similar to black holes in four dimensions and higher. The detailed instabilities are numerically investigated.

  20. The broken string in Anti-de Sitter space

    Science.gov (United States)

    Vegh, David

    2018-02-01

    This paper describes an efficient method for solving the classical string equations of motion in (2+1)-dimensional anti-de Sitter spacetime. Exact string solutions are identified that are the analogs of piecewise linear strings in flat space. They can be used to approximate any smooth string motion to arbitrary accuracy. Cusps on the string move with the speed of light and their collisions are described by a reflection formula. Explicit examples are shown with the string ending on two boundary quarks. The technique is ideally suited for numerical simulations.

  1. Cosmic censorship of rotating Anti-de Sitter black hole

    Energy Technology Data Exchange (ETDEWEB)

    Gwak, Bogeun; Lee, Bum-Hoon, E-mail: rasenis@sogang.ac.kr, E-mail: bhl@sogang.ac.kr [Center for Quantum Spacetime, Sogang University, Seoul 04107 (Korea, Republic of)

    2016-02-01

    We test the validity of cosmic censorship in the rotating anti-de Sitter black hole. For this purpose, we investigate whether the extremal black hole can be overspun by the particle absorption. The particle absorption will change the mass and angular momentum of the black hole, which is analyzed using the Hamilton-Jacobi equations consistent with the laws of thermodynamics. We have found that the mass of the extremal black hole increases more than the angular momentum. Therefore, the outer horizon of the black hole still exists, and cosmic censorship is valid.

  2. Black hole remnant in asymptotic anti-de Sitter space

    Energy Technology Data Exchange (ETDEWEB)

    Wen, Wen-Yu [Chung Yuan Christian University, Department of Physics, Center for High Energy Physics, Chung Li City (China); National Taiwan University, Leung Center for Cosmology and Particle Astrophysics, Taipei (China); Wu, Shang-Yu [National Chiao Tung University, Department of Electrophysics, Hsinchu (China)

    2015-12-15

    The solution of a remnant was suggested for the black hole ground state after surface gravity is corrected for the loop quantum effect. On the other hand, a Schwarzschild black hole in asymptotic anti-de Sitter space would tunnel into the thermal soliton solution known as the Hawking-Page phase transition. In this letter, we investigate the low temperature phase of a three-dimensional Banados-Teitelboim-Zanelli (BTZ) black hole and four-dimensional AdS Schwarzschild black hole. We find that the thermal soliton is energetically favored rather than the remnant solution at low temperature in three dimensions, while a Planck-size remnant is still possible in four dimensions. Though the BTZ remnant seems energetically disfavored, we argue that it is still possible to find in the overcooled phase if strings were present, and its implication is discussed. (orig.)

  3. Black hole remnant in asymptotic anti-de Sitter space

    Energy Technology Data Exchange (ETDEWEB)

    Wen, Wen-Yu, E-mail: steve.wen@gmail.com [Department of Physics, Center for High Energy Physics, Chung Yuan Christian University, Chung Li City, Taiwan (China); Leung Center for Cosmology and Particle Astrophysics, National Taiwan University, 106, Taipei, Taiwan (China); Wu, Shang-Yu, E-mail: loganwu@gmail.com [Department of Electrophysics, National Chiao Tung University, Hsinchu, Taiwan (China)

    2015-12-21

    The solution of a remnant was suggested for the black hole ground state after surface gravity is corrected for the loop quantum effect. On the other hand, a Schwarzschild black hole in asymptotic anti-de Sitter space would tunnel into the thermal soliton solution known as the Hawking–Page phase transition. In this letter, we investigate the low temperature phase of a three-dimensional Banados–Teitelboim–Zanelli (BTZ) black hole and four-dimensional AdS Schwarzschild black hole. We find that the thermal soliton is energetically favored rather than the remnant solution at low temperature in three dimensions, while a Planck-size remnant is still possible in four dimensions. Though the BTZ remnant seems energetically disfavored, we argue that it is still possible to find in the overcooled phase if strings were present, and its implication is discussed.

  4. Supersymmetry of anti-de Sitter black holes

    International Nuclear Information System (INIS)

    Caldarelli, Marco M.; Klemm, Dietmar

    1999-01-01

    We examine supersymmetry of four-dimensional asymptotically anti-de Sitter (AdS) dyonic black holes in the context of gauged N = 2 supergravity. Our calculations concentrate on black holes with unusual topology and their rotating generalizations, but we also reconsider the spherical rotating dyonic Ker-Newman-AdS black hole, whose supersymmetry properties have previously been investigated by Kostelecky and Perry within another approach. We find that in the case of spherical, toroidal or cylindrical event horizon topology, the black holes must rotate in order to preserve some supersymmetry; the non-rotating supersymmetric configurations representing naked singularities. However, we show that this is no more true for black holes whose event horizons are Riemann surfaces of genus g > 1, where we find a non-rotating extremal solitonic black hole carrying magnetic charge and permitting one Killing spinor. For the non-rotating supersymmetric configurations of various topologies, all Killing spinors are explicitly constructed

  5. Flow equation, conformal symmetry, and anti-de Sitter geometry

    Science.gov (United States)

    Aoki, Sinya; Yokoyama, Shuichi

    2018-03-01

    We argue that the anti-de Sitter (AdS) geometry in d+1 dimensions naturally emerges from an arbitrary conformal field theory in d dimensions using the free flow equation. We first show that an induced metric defined from the flowed field generally corresponds to the quantum information metric, called the Bures or Helstrom metric, if the flowed field is normalized appropriately. We next verify that the induced metric computed explicitly with the free flow equation always becomes the AdS metric when the theory is conformal. We finally prove that the conformal symmetry in d dimensions converts to the AdS isometry in d+1 dimensions after d-dimensional quantum averaging. This guarantees the emergence of AdS geometry without explicit calculation.

  6. Supersymmetry breaking in anti-de Sitter space

    International Nuclear Information System (INIS)

    Burgess, C.P.

    1985-01-01

    The quantum properties of supergravity theories on a four-dimensional anti-de Sitter space background are investigated. It is shown that if supersymmetry is unbroken at the classical level then the one-loop vacuum is supersymmetric if and only if the one-loop vacuum energy vanishes. The unrenormalized vacuum energy is calculated and shown to be zero in an arbitrary theory if the classical background in supersymmetric, thereby showing that one-loop corrections always respect the supersymmetry of the vacuum. Although the bare vacuum energy vanishes, the renormalized vacuum energy need not. The renormalized vacuum energy is shown to be determined by the infinite part of the one-loop effective action, and so is easily calculable. The resulting quantum correction to the background curvature is calculated and shown to vanish in any supersymmetric one-loop finite theory on AdS. In all cases calculated the quantum corrections, if nonzero, tend to reduce the background curvature

  7. Heavy-Ion Collisions and Black Holes in Anti-de-Sitter Space

    CERN Document Server

    Ellis, John R.

    1999-07-02

    Recent developments linking non-perturbative quantum gauge theories in Minkowski space to classical gravity theories in anti-de-Sitter space are reviewed at a simple level. It is suggested how these spectacular advances may be extended to discuss the quark-gluon phase transition in terms of black holes in anti-de-Sitter space, with possible relevance to heavy-ion collisions.

  8. de Sitter special relativity

    International Nuclear Information System (INIS)

    Aldrovandi, R; Almeida, J P Beltran; Pereira, J G

    2007-01-01

    A special relativity based on the de Sitter group is introduced, which is a theory that might hold up in the presence of a non-vanishing cosmological constant. Like ordinary special relativity, it retains the quotient character of spacetime, and a notion of homogeneity. As a consequence, the underlying spacetime will be a de Sitter spacetime, whose associated kinematics will differ from that of ordinary special relativity. The corresponding modified notions of energy and momentum are obtained, and the exact relationship between them, which is invariant under a re-scaling of the involved quantities, explicitly exhibited. Since the de Sitter group can be considered a particular deformation of the Poincare group, this theory turns out to be a specific kind of deformed (or doubly) special relativity. Some experimental consequences, as well as the causal structure of spacetime-modified by the presence of the de Sitter horizon-are briefly discussed

  9. Rotation induced break down of Weak Equivalence Principle in Schwarzschild?(Anti-) de Sitter Geometry

    Science.gov (United States)

    Khayrul, Hasan, M.; Sultana, Kausari; Shahjalal, Md.

    2017-10-01

    We probe the plausibility of weak equivalence principle for a circular motion at the radial distance of photon sphere of the Schwarzschild?(Anti-)de Sitter black hole. We switch the static Schwarzschild?(Anti-)de Sitter space-time to rotational by means of the transformation with constant angular velocity. The fiducial observers revolving along the trajectory of photon orbit of the Schwarzschild?(Anti-)de Sitter black hole are supposed to agree on the result of any physical experiment when their angular velocities are uniform, which give rise to the constancy in their accelerations, meaning the observers are equivalent. Our study, in contrast, finds that the observers do not measure similar results, claiming the invalidity of the principle of weak equivalence. However, the aim of our work is not to defy the principle absolutely, rather we focus our attention on the very cause for which the dispute arises, namely the rotational motion.

  10. Phase space localization for anti-de Sitter quantum mechanics and its zero curvature limit

    Science.gov (United States)

    Elgradechi, Amine M.

    1993-01-01

    Using techniques of geometric quantization and SO(sub 0)(3,2)-coherent states, a notion of optimal localization on phase space is defined for the quantum theory of a massive and spinning particle in anti-de Sitter space time. It is shown that this notion disappears in the zero curvature limit, providing one with a concrete example of the regularizing character of the constant (nonzero) curvature of the anti-de Sitter space time. As a byproduct a geometric characterization of masslessness is obtained.

  11. De Sitter projective relativity

    CERN Document Server

    Licata, Ignazio; Benedetto, Elmo

    2017-01-01

    This book presents the Projective approach to de Sitter Relativity. It traces the development of renewed interest in models of the universe at constant positive curvature such as "vacuum" geometry. The De Sitter Theory of Relativity, formulated in 1917 with Willem De Sitter's solution of the Einstein equations, was used in different fields during the 1950s and 1960s, in the work of H. Bacry, J.M. LevyLeblond and F.Gursey, to name some important contributors. From the 1960s to 1980s, L. Fantappié and G. Arcidiacono provided an elegant group approach to the De Sitter universe putting the basis for special and general projective relativity. Today such suggestions flow into a unitary scenario, and this way the De Sitter Relativity is no more a "missing opportunity" (F. Dyson, 1972), but has a central role in theoretical physics. In this volume a systematic presentation is given of the De Sitter Projective relativity, with the recent developments in projective general relativity and quantum cosmology.

  12. Some exact solutions for maximally symmetric topological defects in Anti de Sitter space

    Science.gov (United States)

    Alvarez, Orlando; Haddad, Matthew

    2018-03-01

    We obtain exact analytical solutions for a class of SO( l) Higgs field theories in a non-dynamic background n-dimensional anti de Sitter space. These finite transverse energy solutions are maximally symmetric p-dimensional topological defects where n = ( p + 1) + l. The radius of curvature of anti de Sitter space provides an extra length scale that allows us to study the equations of motion in a limit where the masses of the Higgs field and the massive vector bosons are both vanishing. We call this the double BPS limit. In anti de Sitter space, the equations of motion depend on both p and l. The exact analytical solutions are expressed in terms of standard special functions. The known exact analytical solutions are for kink-like defects ( p = 0 , 1 , 2 , . . . ; l = 1), vortex-like defects ( p = 1 , 2 , 3; l = 2), and the 't Hooft-Polyakov monopole ( p = 0; l = 3). A bonus is that the double BPS limit automatically gives a maximally symmetric classical glueball type solution. In certain cases where we did not find an analytic solution, we present numerical solutions to the equations of motion. The asymptotically exponentially increasing volume with distance of anti de Sitter space imposes different constraints than those found in the study of defects in Minkowski space.

  13. Anti-De Sitter Space, Thermal Phase Transition, and Confinement in Gauge Theories

    Science.gov (United States)

    Witten, Edward

    2014-03-01

    The correspondence between supergravity (and string theory) on AdS space and boundary conformal field theory relates the thermodynamics of N = 4 super Yang-Mills theory in four dimensions to the thermodynamics of Schwarzschild black holes in Anti-de Sitter space. In this description, quantum phenomena such as the spontaneous breaking of the center of the gauge group, magnetic confinement, and the mass gap are coded in classical geometry. The correspondence makes it manifest that the entropy of a very large AdS Schwarzschild black hole must scale "holographically" with the volume of its horizon. By similar methods, one can also make a speculative proposal for the description of large N gauge theories in four dimensions without supersymmetry.

  14. Quantum corrections in thermal states of fermions on anti-de Sitter space-time

    Science.gov (United States)

    Ambruş, Victor E.; Winstanley, Elizabeth

    2017-12-01

    We study the energy density and pressure of a relativistic thermal gas of massless fermions on four-dimensional Minkowski and anti-de Sitter space-times using relativistic kinetic theory. The corresponding quantum field theory quantities are given by components of the renormalized expectation value of the stress-energy tensor operator acting on a thermal state. On Minkowski space-time, the renormalized vacuum expectation value of the stress-energy tensor is by definition zero, while on anti-de Sitter space-time the vacuum contribution to this expectation value is in general nonzero. We compare the properties of the vacuum and thermal expectation values of the energy density and pressure for massless fermions and discuss the circumstances in which the thermal contribution dominates over the vacuum one.

  15. Entanglement entropy of black holes and anti-de Sitter space/conformal-field-theory correspondence.

    Science.gov (United States)

    Solodukhin, Sergey N

    2006-11-17

    A recent proposal by Ryu and Takayanagi for a holographic interpretation of entanglement entropy in conformal field theories dual to supergravity on anti-de Sitter space is generalized to include entanglement entropy of black holes living on the boundary of anti-de Sitter space. The generalized proposal is verified in boundary dimensions d=2 and d=4 for both the uv-divergent and uv-finite terms. In dimension d=4 an expansion of entanglement entropy in terms of size L of the subsystem outside the black hole is considered. A new term in the entropy of dual strongly coupled conformal-field theory, which universally grows as L(2)lnL and is proportional to the value of the obstruction tensor at the black hole horizon, is predicted.

  16. Delayed collapses of Bose-Einstein condensates in relation to anti-de Sitter gravity.

    Science.gov (United States)

    Biasi, Anxo F; Mas, Javier; Paredes, Angel

    2017-03-01

    We numerically investigate spherically symmetric collapses in the Gross-Pitaevskii equation with attractive nonlinearity in a harmonic potential. Even below threshold for direct collapse, the wave function bounces off from the origin and may eventually become singular after a number of oscillations in the trapping potential. This is reminiscent of the evolution of Einstein gravity sourced by a scalar field in anti de Sitter space where collapse corresponds to black-hole formation. We carefully examine the long time evolution of the wave function for continuous families of initial states in order to sharpen out this qualitative coincidence which may bring new insights in both directions. On the one hand, we comment on possible implications for the so-called Bosenova collapses in cold atom Bose-Einstein condensates. On the other hand, Gross-Pitaevskii provides a toy model to study the relevance of either the resonance conditions or the nonlinearity for the problem of anti de Sitter instability.

  17. Stability of anti-de sitter space in Einstein-Gauss-Bonnet gravity.

    Science.gov (United States)

    Deppe, Nils; Kolly, Allison; Frey, Andrew; Kunstatter, Gabor

    2015-02-20

    Recently it has been argued that in Einstein gravity anti-de Sitter spacetime is unstable against the formation of black holes for a large class of arbitrarily small perturbations. We examine the effects of including a Gauss-Bonnet term. In five dimensions, spherically symmetric Einstein-Gauss-Bonnet gravity has two key features: Choptuik scaling exhibits a radius gap, and the mass function goes to a finite value as the horizon radius vanishes. These suggest that black holes will not form dynamically if the total mass-energy content of the spacetime is too small, thereby restoring the stability of anti-de Sitter spacetime in this context. We support this claim with numerical simulations and uncover a rich structure in horizon radii and formation times as a function of perturbation amplitude.

  18. Violating the Weak Cosmic Censorship Conjecture in Four-Dimensional Anti-de Sitter Space

    Science.gov (United States)

    Crisford, Toby; Santos, Jorge E.

    2017-05-01

    We consider time-dependent solutions of the Einstein-Maxwell equations using anti-de Sitter (AdS) boundary conditions, and provide the first counterexample to the weak cosmic censorship conjecture in four spacetime dimensions. Our counterexample is entirely formulated in the Poincaré patch of AdS. We claim that our results have important consequences for quantum gravity, most notably to the weak gravity conjecture.

  19. Anti-de-Sitter regular electric multipoles: towards Einstein-Maxwell-AdS solitons

    OpenAIRE

    Herdeiro, Carlos; Radu, Eugen

    2015-01-01

    We discuss electrostatics in Anti-de-Sitter ($AdS$) spacetime, in global coordinates. We observe that the multipolar expansion has two crucial differences to that in Minkowski spacetime. First, there are everywhere regular solutions, with finite energy, for every multipole moment except for the monopole. Second, all multipole moments decay with the same inverse power of the areal radius, $1/r$, as spatial infinity is approached. The first observation suggests there may be regular, self-gravit...

  20. Viscous plasma evolution from gravity using anti-de sitter/conformal-field-theory correspondence.

    Science.gov (United States)

    Janik, Romuald A

    2007-01-12

    We analyze the anti-de Sitter/conformal-field-theory dual geometry of an expanding boost-invariant plasma. We show that the requirement of nonsingularity of the dual geometry for leading and subasymptotic times predicts, without any further assumptions about gauge theory dynamics, hydrodynamic expansion of the plasma with viscosity coefficient exactly matching the one obtained earlier in the static case by Policastro, Son, and Starinets.

  1. Discrete Torsion, (Anti) de Sitter D{sub 4}-Brane and Tunneling

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Abhishek K.; Pandey, P.K.; Singh, Sunita; Kar, Supriya, E-mail: skkar@physics.du.ac.in

    2014-06-15

    We obtain quantum geometries on a vacuum created pair of a (DD{sup ¯}){sub 3}-brane, at a Big Bang singularity, by a local two form on a D{sub 4}-brane. In fact our analysis is provoked by an established phenomenon leading to a pair creation by a gauge field at a black hole horizon by Stephen Hawking in 1975. Importantly, the five dimensional microscopic black holes are described by an effective non-perturbative curvature underlying a discrete torsion in a second order formalism. In the case for a non-propagating torsion, the effective curvature reduces to Riemannian, which in a low energy limit may describe Einstein vacuum in the formalism. In particular, our analysis suggests that a non-trivial space begin with a hot de Sitter brane-Universe underlying a nucleation of a vacuum pair of (DD{sup ¯})-instanton at a Big Bang. A pair of instanton nucleats a D-particle which in turn combines with an anti D-particle to describe a D-string and so on. The nucleation of a pair of higher dimensional pair of brane/anti-brane from a lower dimensional pair may be viewed via an expansion of the brane-Universe upon time. It is in conformity with the conjecture of a branes within a brane presumably in presence of the non-zero modes of two form. Interestingly, we perform a thermal analysis underlying various emergent quantum de Sitter vacua on a D{sub 4}-brane and argue for the plausible tunneling geometries underlying a thermal equilibrium. It is argued that a de Sitter Schwarzschild undergoes quantum tunneling to an AdS-brane Schwarzschild via Nariai and de Sitter topological black hole.

  2. Towards a quantization of gauge fields on de Sitter group by functional integral method

    International Nuclear Information System (INIS)

    Chiritoiu, Viorel; Zet, Gheorghe

    2008-01-01

    A formulation of the de Sitter symmetry as a purely inner symmetry defined on a fixed Minkowski space-time is presented. We define the generators of the de Sitter group and write the structure equations using a constant deformation parameter λ. The conserved gauge currents are calculated, and their physical meaning is given. Local gauge transformations and the corresponding covariant derivative depending on the gauge fields are also obtained. We study the behavior of gauge fields, the torsion and curvature tensors and give a regularization technique in terms of the ζ function. (orig.)

  3. Three-dimensional black hole from a stringy anti endash de Sitter background

    International Nuclear Information System (INIS)

    Hjelmeland, S.E.

    1997-01-01

    A new black hole solution in 2+1 dimensions is found by taking cosmic strings as part of the vacuum structure of the anti endash de Sitter space-time. The solution has a structure that in many ways is similar to that of the Reissner-Nordstroem solution. With a vanishing cosmological constant, a space-time with a black hole of infinite extension appears with the inner horizon playing the role of a cosmological event horizon. The timelike and null geodesics are discussed. In particular it is shown that photons may follow conic sections. copyright 1997 The American Physical Society

  4. Generic cosmic-censorship violation in anti-de Sitter space.

    Science.gov (United States)

    Hertog, Thomas; Horowitz, Gary T; Maeda, Kengo

    2004-04-02

    We consider (four-dimensional) gravity coupled to a scalar field with potential V(phi). The potential satisfies the positive energy theorem for solutions that asymptotically tend to a negative local minimum. We show that for a large class of such potentials, there is an open set of smooth initial data that evolve to naked singularities. Hence cosmic censorship does not hold for certain reasonable matter theories in asymptotically anti-de Sitter spacetimes. The asymptotically flat case is more subtle. We suspect that potentials with a local Minkowski minimum may similarly lead to violations of cosmic censorship in asymptotically flat spacetimes, but we do not have definite results.

  5. Abundant stable gauge field hair for black holes in anti-de Sitter space.

    Science.gov (United States)

    Baxter, J E; Helbling, Marc; Winstanley, Elizabeth

    2008-01-11

    We present new hairy black hole solutions of SU(N) Einstein-Yang-Mills (EYM) theory in asymptotically anti-de Sitter (AdS) space. These black holes are described by N+1 independent parameters and have N-1 independent gauge field degrees of freedom. Solutions in which all gauge field functions have no zeros exist for all N, and for a sufficiently large (and negative) cosmological constant. At least some of these solutions are shown to be stable under classical, linear, spherically symmetric perturbations. Therefore there is no upper bound on the amount of stable gauge field hair with which a black hole in AdS can be endowed.

  6. Bjorken flow from an anti-de Sitter space Schwarzschild black hole.

    Science.gov (United States)

    Alsup, James; Siopsis, George

    2008-07-18

    We consider a large black hole in asymptotically anti-de Sitter spacetime of arbitrary dimension with a Minkowski boundary. By performing an appropriate slicing as we approach the boundary, we obtain via holographic renormalization a gauge theory fluid obeying Bjorken hydrodynamics in the limit of large longitudinal proper time. The metric we obtain reproduces to leading order the metric recently found as a direct solution of the Einstein equations in five dimensions. Our results are also in agreement with recent exact results in three dimensions.

  7. Correspondence between nonrelativistic anti-de Sitter space and conformal field theory, and aging-gravity duality.

    Science.gov (United States)

    Minic, Djordje; Pleimling, Michel

    2008-12-01

    We point out that the recent discussion of nonrelativistic anti-de Sitter space and conformal field theory correspondence has a direct application in nonequilibrium statistical physics, a fact which has not been emphasized in the recent literature on the subject. In particular, we propose a duality between aging in systems far from equilibrium characterized by the dynamical exponent z=2 and gravity in a specific background. The key ingredient in our proposal is the recent geometric realization of the Schrödinger group. We also discuss the relevance of the proposed correspondence for the more general aging phenomena in systems where the value of the dynamical exponent is different from 2.

  8. The de Sitter relativistic top theory

    International Nuclear Information System (INIS)

    Armenta, J.; Nieto, J.A.

    2005-01-01

    We discuss the relativistic top theory from the point of view of the de Sitter (or anti-de Sitter) group. Our treatment rests on the Hanson-Regge spherical relativistic top Lagrangian formulation. We propose an alternative method for studying spinning objects via Kaluza-Klein theory. In particular, we derive the relativistic top equations of motion starting with the geodesic equation for a point particle in 4+N dimensions. We compare our approach with Fukuyama's formulation of spinning objects, which is also based on Kaluza-Klein theory. We also report a generalization of our approach to a 4+N+D dimensional theory

  9. Reissner–Nordström Anti-de Sitter Black Holes in Mimetic F(R Gravity

    Directory of Open Access Journals (Sweden)

    V. K. Oikonomou

    2016-05-01

    Full Text Available In this paper, we study under which conditions the Reissner–Nordström anti-de Sitter black hole can be a solution of the vacuum mimetic F ( R gravity with Lagrange multiplier and mimetic scalar potential. As the author demonstrates, the resulting picture in the mimetic F ( R gravity case is a trivial extension of the standard F ( R approach, and in effect, the metric perturbations in the mimetic F ( R gravity case, for the Reissner–Nordström anti-de Sitter black hole metric, at the first order of the perturbed variables are the same at the leading order.

  10. Real forms of complex quantum anti-de-Sitter algebra Uq(Sp(4;C)) and their contraction schemes

    International Nuclear Information System (INIS)

    Lukierski, J.; Nowicki, A.; Ruegg, H.

    1991-01-01

    We describe four types of inner involutions of the Cartan-Weyl basis providing (for vertical strokeqvertical stroke=1 and q real) three types of real quantum Lie algebras: U q (O(3, 2)) (quantum D=4 anti-de-Sitter), U q (O(4, 1)) (quantum D=4 de-Sitter) and U q (O(5)). We give also two types of inner involutions of the Cartan-Chevalley basis of U q (Sp(4; C)) which cannot be extended to inner involutions of the Cartan-Weyl basis. We outline twelve contraction schemes for quantum D=4 anti-de-Sitter algebra. All these contractions provide four commuting translation generators, but only two (one for vertical strokeqvertical stroke=1, the second for q real) lead to the quantum Poincare algebra with an undeformed space rotation O(3) subalgebra. (orig.)

  11. Anti-de Sitter gravity associated with the supergroup $SU(1,1|2)\\times SU(1,1|2)$

    OpenAIRE

    David, Justin R.

    1999-01-01

    We construct the anti-de Sitter supergravity in three dimensions associated with the supergroup $SU(1,1|2)\\times SU(1,1|2)$. The field content and the action are inferred using the fact that $AdS$ supergravity theories in three dimensions are Chern-Simons theories.

  12. Hawking evaporation time scale of topological black holes in anti-de Sitter spacetime

    Energy Technology Data Exchange (ETDEWEB)

    Ong, Yen Chin, E-mail: yenchin.ong@nordita.org

    2016-02-15

    It was recently pointed out that if an absorbing boundary condition is imposed at infinity, an asymptotically anti-de Sitter Schwarzschild black hole with a spherical horizon takes only a finite amount of time to evaporate away even if its initial mass is arbitrarily large. We show that this is a rather generic property in AdS spacetimes: regardless of their horizon topologies, neutral AdS black holes in general relativity take about the same amount of time to evaporate down to the same size of order L, the AdS length scale. Our discussion focuses on the case in which the black hole has toral event horizon. A brief comment is made on the hyperbolic case, i.e. for black holes with negatively curved horizons.

  13. Nonlinear Evolution and Final Fate of Charged Anti-de Sitter Black Hole Superradiant Instability.

    Science.gov (United States)

    Bosch, Pablo; Green, Stephen R; Lehner, Luis

    2016-04-08

    We describe the full nonlinear development of the superradiant instability for a charged massless scalar field coupled to general relativity and electromagnetism, in the vicinity of a Reissner-Nordström-anti-de Sitter black hole. The presence of the negative cosmological constant provides a natural context for considering perfectly reflecting boundary conditions and studying the dynamics as the scalar field interacts repeatedly with the black hole. At early times, small superradiant perturbations grow as expected from linearized studies. Backreaction then causes the black hole to lose charge and mass until the perturbation becomes nonsuperradiant, with the final state described by a stable hairy black hole. For large gauge coupling, the instability extracts a large amount of charge per unit mass, resulting in greater entropy increase. We discuss the implications of the observed behavior for the general problem of superradiance in black hole spacetimes.

  14. Spin Interaction under the Collision of Two Kerr-(Anti-de Sitter Black Holes

    Directory of Open Access Journals (Sweden)

    Bogeun Gwak

    2017-12-01

    Full Text Available We investigate herein the spin interaction during collisions between Kerr-(anti-de Sitter black holes. The spin interaction potential depends on the relative rotation directions of the black holes, and this potential can be released as gravitational radiation upon collision. The energy of the radiation depends on the cosmological constant and corresponds to the spin interaction potential in the limit that one of the black holes has negligibly small mass and angular momentum. We then determine the approximate overall behaviors of the upper bounds on the radiation using thermodynamics. The results indicate that the spin interaction can consistently contribute to the radiation. In addition, the radiation depends on the stability of the black hole produced by the collision.

  15. Null polygonal Wilson loops and minimal surfaces in Anti-de-Sitter space

    International Nuclear Information System (INIS)

    Alday, Luis F.; Maldacena, Juan

    2009-01-01

    We consider minimal surfaces in three dimensional anti-de-Sitter space that end at the AdS boundary on a polygon given by a sequence of null segments. The problem can be reduced to a certain generalized Sinh-Gordon equation and to SU(2) Hitchin equations. We describe in detail the mathematical problem that needs to be solved. This problem is mathematically the same as the one studied by Gaiotto, Moore and Neitzke in the context of the moduli space of certain supersymmetric theories. Using their results we can find the explicit answer for the area of a surface that ends on an eight-sided polygon. Via the gauge/gravity duality this can also be interpreted as a certain eight-gluon scattering amplitude at strong coupling. In addition, we give fairly explicit solutions for regular polygons.

  16. Simulation of black hole collisions in asymptotically Anti-de Sitter spacetimes.

    Science.gov (United States)

    Bantilan, Hans; Romatschke, Paul

    2015-02-27

    We present results from the evolution of spacetimes that describe the merger of asymptotically global anti-de Sitter black holes in 5D with an SO(3) symmetry. Prompt scalar field collapse provides us with a mechanism for producing distinct trapped regions on the initial slice, associated with black holes initially at rest. We evolve these black holes towards a merger, and follow the subsequent ring down. The boundary stress tensor of the dual conformal field theory is conformally related to a stress tensor in Minkowski space that inherits an axial symmetry from the bulk SO(3). We compare this boundary stress tensor to its hydrodynamic counterpart with viscous corrections of up to second order, and compare the conformally related stress tensor to ideal hydrodynamic simulations in Minkowski space, initialized at various time slices of the boundary data. Our findings reveal far-from-hydrodynamic behavior at early times, with a transition to ideal hydrodynamics at late times.

  17. Non-topological gravitating defects in five-dimensional anti-de Sitter space

    CERN Document Server

    Giovannini, Massimo

    2006-01-01

    A class of five-dimensional warped solutions is presented. The geometry is everywhere regular and tends to five-dimensional anti-de Sitter space for large absolute values of the bulk coordinate. The physical features of the solutions change depending on the value of an integer parameter. In particular, a set of solutions describes generalized gravitating kinks where the scalar field interpolates between two different minima of the potential. The other category of solutions describes instead gravitating defects where the scalar profile is always finite and reaches the same constant asymptote both for positive and negative values of the bulk coordinate. In this sense the profiles are non-topological. The physical features of the zero modes are discussed.

  18. From the Schwarzschild Anti-de Sitter Black Hole to the Conformal Field Theory

    Directory of Open Access Journals (Sweden)

    Akram Sadat Sefiedgar

    2015-01-01

    Full Text Available The emergence of the quantum gravitational effects in a very high energy regime necessitates some corrections to the thermodynamics of black holes. In this letter, we investigate a possible modification to the thermodynamics of Schwarzschild anti-de Sitter (SAdS black holes due to rainbow gravity model. Using the correspondence between a (d+1-dimensional SAdS black hole and a conformal filed theory in d-dimensional spacetime, one may find the corrections to the Cardy-Verlinde formula from the modified thermodynamics of the black hole. Furthermore, we show that the corrected Cardy-Verlinde formula can also be derived by redefining the Virasoro operator and the central charge.

  19. Graviton n-point functions for UV-complete theories in Anti-de Sitter space

    CERN Document Server

    Brustein, Ram

    2012-01-01

    We calculate graviton n-point functions in an anti-de Sitter black brane background for effective gravity theories whose linearized equations of motion have at most two time derivatives. We compare the n-point functions in Einstein gravity to those in theories whose leading correction is quadratic in the Riemann tensor. The comparison is made for any number of gravitons and for all physical graviton modes in a kinematic region for which the leading correction can significantly modify the Einstein result. We find that the n-point functions of Einstein gravity depend on at most a single angle, whereas those of the corrected theories may depend on two angles. For the four-point functions, Einstein gravity exhibits linear dependence on the Mandelstam variable s versus a quadratic dependence on s for the corrected theory.

  20. The holographic Hadamard condition on asymptotically anti-de Sitter spacetimes

    Science.gov (United States)

    Wrochna, Michał

    2017-12-01

    In the setting of asymptotically anti-de Sitter spacetimes, we consider Klein-Gordon fields subject to Dirichlet boundary conditions, with mass satisfying the Breitenlohner-Freedman bound. We introduce a condition on the b-wave front set of two-point functions of quantum fields, which locally in the bulk amounts to the usual Hadamard condition, and which moreover allows to estimate wave front sets for the holographically induced theory on the boundary. We prove the existence of two-point functions satisfying this condition and show their uniqueness modulo terms that have smooth Schwartz kernel in the bulk and have smooth restriction to the boundary. Finally, using Vasy's propagation of singularities theorem, we prove an analogue of Duistermaat and Hörmander's theorem on distinguished parametrices.

  1. Holographic calculations of Euclidean Wilson loop correlator in Euclidean anti-de Sitter space

    Energy Technology Data Exchange (ETDEWEB)

    Ziama, Sannah [Department of Physics and Astronomy, University of Kentucky,505 Rose Street, Lexington, KY 40506-0055 (United States)

    2015-04-07

    The correlation functions of two or more Euclidean Wilson loops of various shapes in Euclidean anti-de Sitter space are computed by considering the minimal area surfaces connecting the loops. The surfaces are parametrized by Riemann theta functions associated with genus three hyperelliptic Riemann surfaces. In the case of two loops, the distance L by which they are separated can be adjusted by continuously varying a specific branch point of the auxiliary Riemann surface. When L is much larger than the characteristic size of the loops, then the loops are approximately regarded as local operators and their correlator as the correlator of two local operators. Similarly, when a loop is very small compared to the size of another loop, the small loop is considered as a local operator corresponding to a light supergravity mode.

  2. Thermodynamic stability of asymptotically anti-de Sitter rotating black holes in higher dimensions

    International Nuclear Information System (INIS)

    Dolan, Brian P

    2014-01-01

    Conditions for thermodynamic stability of asymptotically anti-de Sitter (AdS) rotating black holes in D-dimensions are determined. Local thermodynamic stability requires not only positivity conditions on the specific heat and the moment of inertia tensor but it is also necessary that the adiabatic compressibility be positive. It is shown that, in the absence of a cosmological constant, neither rotation nor charge is sufficient to ensure full local thermodynamic stability of a black hole. Thermodynamic stability properties of AdS Myers–Perry black holes are investigated for both singly spinning and multi-spinning black holes. Simple expressions are obtained for the specific heat and moment of inertia tensor in any dimension. An analytic expression is obtained for the boundary of the region of parameter space in which such space-times are thermodynamically stable. (paper)

  3. Gravitational quasinormal modes of static Einstein-Gauss-Bonnet anti-de Sitter black holes

    Science.gov (United States)

    Ma, Hong; Li, Jin

    2018-04-01

    In this paper, we describe quasinormal modes (QNMs) for gravitational perturbations of Einstein-Gauss-Bonnet black holes (BHs) in higher dimensional spacetimes, and derive the corresponding parameters of such black holes in three types of spacetime (flat, de Sitter (dS) and anti-de Sitter (AdS)). Our attention is concentrated on discussing the (in)stability of Einstein-Gauss-Bonnet AdS BHs through the temporal evolution of all types of gravitational perturbation fields (tensor, vector and scalar). It is concluded that the potential functions in vector and scalar gravitational perturbations have negative regions, which suppress quasinormal ringing. Furthermore, the influences of the Gauss-Bonnet coupling parameter α, the number of dimensions n and the angular momentum quantum number l on the Einstein-Gauss-Bonnet AdS BHs quasinormal spectrum are analyzed. The QNM frequencies have greater oscillation and lower damping rate with the growth of α. This indicates that QNM frequencies become increasingly unstable with large α. Meanwhile, the dynamic evolutions of the perturbation field are compliant with the results of computation from the Horowitz and Hubeny method. Because the number of extra dimensions is connected with the string scale, the relationship between α and properties of Einstein-Gauss-Bonnet AdS BHs might be beneficial for the exploitation of string theory and extra-dimensional brane worlds. Supported by FAPESP (2012/08934-0), National Natural Science Foundation of China (11205254, 11178018, 11375279, 11605015), the Natural Science Foundation Project of CQ CSTC (2011BB0052), and the Fundamental Research Funds for the Central Universities (106112016CDJXY300002, 106112017CDJXFLX0014, CDJRC10300003)

  4. Eikonal instability of Gauss-Bonnet-(anti-)-de Sitter black holes

    Science.gov (United States)

    Konoplya, R. A.; Zhidenko, A.

    2017-05-01

    Here we have shown that asymptotically anti-de Sitter (AdS) black holes in the Einstein-Gauss-Bonnet (GB) theory are unstable under linear perturbations of space-time in some region of parameters. This (eikonal) instability develops at high multipole numbers. We found the exact parametric regions of the eikonal instability and extended this consideration to asymptotically flat and de Sitter cases. The approach to the threshold of instability is driven by purely imaginary quasinormal modes, which are similar to those found recently in Grozdanov, Kaplis, and Starinets, [J. High Energy Phys. 07 (2016) 151, 10.1007/JHEP07(2016)151] for the higher curvature corrected black hole with the planar horizon. The found instability may indicate limits of holographic applicability of the GB-AdS backgrounds. Recently, through the analysis of critical behavior in AdS space-time in the presence of the Gauss-Bonnet term, it was shown [Deppe et al, Phys. Rev. Lett. 114, 071102 (2015), 10.1103/PhysRevLett.114.071102], that, if the total energy content of the AdS space-time is small, then no black holes can be formed with mass less than some critical value. A similar mass gap was also found when considering collapse of mass shells in asymptotically flat Gauss-Bonnet theories [Frolov, Phys. Rev. Lett. 115, 051102 (2015), 10.1103/PhysRevLett.115.051102]. The found instability of all sufficiently small Einstein-Gauss-Bonnet-AdS, dS and asymptotically flat black holes may explain the existing mass gaps in their formation.

  5. Geodesic Motions near a Five-dimensional Reissner–Nordström Anti-de Sitter black hole

    International Nuclear Information System (INIS)

    Guha, Sarbari; Bhattacharya, Pinaki

    2012-01-01

    We have studied the geodesics of neutral particles near a non-rotating, charged five-dimensional Reissner–Nordström Anti-de Sitter black hole using the effective potential analysis and the dynamical systems analysis. The effective potential analysis is used to determine the location of the horizon and to study radial and circular trajectories. The dynamical systems method is used to determine the stability and the fixed points of the phase trajectories.

  6. Stable monopole and dyon solutions in the einstein-yang-mills theory in asymptotically anti-de sitter space

    Science.gov (United States)

    Bjoraker; Hosotani

    2000-02-28

    A continuum of new monopole and dyon solutions in the Einstein-Yang-Mills theory in asymptotically anti-de Sitter space are found. They are regular everywhere and specified by their mass and their non-Abelian electric and magnetic charges. A class of monopole solutions which have no node in non-Abelian magnetic fields is shown to be stable against spherically symmetric linear perturbations.

  7. Perturbation of Large Anti-deSitter Black Holes and AdS/CFT Correspondence

    Science.gov (United States)

    Ahmadzadegan, Aida

    As the main goal of this thesis, the canonical form of the perturbation metric of anti-de Sitter black holes in four dimensions is derived by choosing the Regge-Wheeler gauge in the standard Schwarzschild coordinates (t, r, theta, ϕ). By assuming the perturbations to be small, the differential equations governing the perturbations are obtained from the equations deltaRmunu(h ) = 0. Then, by taking the limit of m > > R where R is the radius of AdS space, the perturbation metric and field equations of large AdS black holes are found. Finally, under the shadow of AdS/CFT correspondence, these perturbations can be compared to their corresponding three-dimensional theory of fluid dynamics on the dual space, R x S2. Furthermore, by using the definitions of stress-energy tensor and its perturbation, we can find energy density, pressure and shear viscosity which are the quantities we need to describe the behavior of the fluid on the boundary of the AdS space.

  8. Thin-shell bubbles and information loss problem in anti de Sitter background

    Energy Technology Data Exchange (ETDEWEB)

    Sasaki, Misao [Yukawa Institute for Theoretical Physics,Kyoto University, Kyoto 606-8502 (Japan); Tomsk State Pedagogical University,634050 Tomsk (Russian Federation); Yeom, Dong-han [Yukawa Institute for Theoretical Physics,Kyoto University, Kyoto 606-8502 (Japan); Leung Center for Cosmology and Particle Astrophysics, National Taiwan University,Taipei 10617, Taiwan (China)

    2014-12-24

    We study the motion of thin-shell bubbles and their tunneling in anti de Sitter (AdS) background. We are interested in the case when the outside of a shell is a Schwarzschild-AdS space (false vacuum) and the inside of it is an AdS space with a lower vacuum energy (true vacuum). If a collapsing true vacuum bubble is created, classically it will form a Schwarzschild-AdS black hole. However, this collapsing bubble can tunnel to a bouncing bubble that moves out to spatial infinity. Then, although the classical causal structure of a collapsing true vacuum bubble has the singularity and the event horizon, quantum mechanically the wavefunction has support for a history without any singularity nor event horizon which is mediated by the non-perturbative, quantum tunneling effect. This may be regarded an explicit example that shows the unitarity of an asymptotic observer in AdS, while a classical observer who only follows the most probable history effectively lose information due to the formation of an event horizon.

  9. Spherical and planar three-dimensional anti-de Sitter black holes

    International Nuclear Information System (INIS)

    Zanchin, Vilson T; Miranda, Alex S

    2004-01-01

    The technique of dimensional reduction was used in a recent paper (Zanchin V T, Kleber A and Lemos J P S 2002 Phys. Rev. D 66 064022) where a three-dimensional (3D) Einstein-Maxwell-dilaton theory was built from the usual four-dimensional (4D) Einstein-Maxwell-Hilbert action for general relativity. Starting from a class of 4D toroidal black holes in asymptotically anti-de Sitter (AdS) spacetimes several 3D black holes were obtained and studied in such a context. In the present work we choose a particular case of the 3D action which presents Maxwell field, dilaton field and an extra scalar field, besides gravity field and a negative cosmological constant, and obtain new 3D static black hole solutions whose horizons may have spherical or planar topology. We show that there is a 3D static spherically symmetric solution analogous to the 4D Reissner-Nordstroem-AdS black hole, and obtain other new 3D black holes with planar topology. From the static spherical solutions, new rotating 3D black holes are also obtained and analysed in some detail

  10. Quintessence Reissner Nordström Anti de Sitter Black Holes and Joule Thomson Effect

    Science.gov (United States)

    Ghaffarnejad, H.; Yaraie, E.; Farsam, M.

    2018-02-01

    In this work we investigate corrections of the quintessence regime of the dark energy on the Joule-Thomson (JT) effect of the Reissner Nordström anti de Sitter (RNAdS) black hole. The quintessence dark energy has equation of state as p q = ω ρ q in which -1Hawking temperature on the T-P plan. We determine position of the inverse point versus different numerical values of the mass M and the charge Q of the quintessence AdS RN black hole. The cooling-heating phase transition (JT effect) is happened for M > Q in which the causal singularity is still covered by the horizon. Our calculations show sensitivity of the inverse point {T i , P i } position on the T-P plan to existence of the quintessence dark energy just for large numerical values of the AdS RN black holes charge Q. In other words the quintessence dark energy dose not affect on position of the inverse point when the AdS RN black hole takes on small charges.

  11. Covariant anomalies and Hawking radiation from charged rotating black strings in anti-de Sitter spacetimes

    International Nuclear Information System (INIS)

    Peng Junjin; Wu Shuangqing

    2008-01-01

    Motivated by the success of the recently proposed method of anomaly cancellation to derive Hawking fluxes from black hole horizons of spacetimes in various dimensions, we have further extended the covariant anomaly cancellation method shortly simplified by Banerjee and Kulkarni to explore the Hawking radiation of the (3+1)-dimensional charged rotating black strings and their higher dimensional extensions in anti-de Sitter spacetimes, whose horizons are not spherical but can be toroidal, cylindrical or planar, according to their global identifications. It should be emphasized that our analysis presented here is very general in the sense that the determinant of the reduced (1+1)-dimensional effective metric from these black strings need not be equal to one (√(-g)≠1). Our results indicate that the gauge and energy-momentum fluxes needed to cancel the (1+1)-dimensional covariant gauge and gravitational anomalies are compatible with the Hawking fluxes. Besides, thermodynamics of these black strings are studied in the case of a variable cosmological constant

  12. Dirac perturbations on Schwarzschild-anti-de Sitter spacetimes: Generic boundary conditions and new quasinormal modes

    Science.gov (United States)

    Wang, Mengjie; Herdeiro, Carlos; Jing, Jiliang

    2017-11-01

    We study Dirac quasinormal modes of Schwarzschild-anti-de Sitter (Schwarzschild-AdS) black holes, following the generic principle for allowed boundary conditions proposed in [M. Wang, C. Herdeiro, and M. O. P. Sampaio, Phys. Rev. D 92, 124006 (2015)., 10.1103/PhysRevD.92.124006]. After deriving the equations of motion for Dirac fields on the aforementioned background, we impose vanishing energy flux boundary conditions to solve these equations. We find a set of two Robin boundary conditions are allowed. These two boundary conditions are used to calculate Dirac normal modes on empty AdS and quasinormal modes on Schwarzschild-AdS black holes. In the former case, we recover the known normal modes of empty AdS; in the latter case, the two sets of Robin boundary conditions lead to two different branches of quasinormal modes. The impact on these modes of the black hole size, the angular momentum quantum number and the overtone number are discussed. Our results show that vanishing energy flux boundary conditions are a robust principle, applicable not only to bosonic fields but also to fermionic fields.

  13. Rainbow valley of colored (anti) de Sitter gravity in three dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Gwak, Seungho; Joung, Euihun; Mkrtchyan, Karapet; Rey, Soo-Jong [School of Physics & Astronomy and Center for Theoretical Physics, Seoul National University,Seoul 08826 (Korea, Republic of); Gauge, Gravity & Strings, Center for Theoretical Physics of the Universe,Institute for Basic Sciences,Daejeon 34047 (Korea, Republic of)

    2016-04-11

    We propose a theory of three-dimensional (anti) de Sitter gravity carrying Chan-Paton color charges. We define the theory by Chern-Simons formulation with the gauge algebra (gl{sub 2}⊕gl{sub 2})⊗u(N), obtaining a color-decorated version of interacting spin-one and spin-two fields. We also describe the theory in metric formulation and show that, among N{sup 2} massless spin-two fields, only the singlet one plays the role of metric graviton whereas the rest behave as colored spinning matter that strongly interacts at large N. Remarkably, these colored spinning matter acts as Higgs field and generates a non-trivial potential of staircase shape. At each extremum labelled by k=0,…,[((N−1)/2)], the u(N) color gauge symmetry is spontaneously broken down to u(N−k)⊕u(k) and provides different (A)dS backgrounds with the cosmological constants ((N/(N−2k))){sup 2} Λ. When this symmetry breaking takes place, the spin-two Goldstone modes combine with (or are eaten by) the spin-one gauge fields to become partially-massless spin-two fields. We discuss various aspects of this theory and highlight physical implications.

  14. Simple de Sitter solutions

    International Nuclear Information System (INIS)

    Silverstein, Eva

    2008-01-01

    We present a framework for de Sitter model building in type IIA string theory, illustrated with specific examples. We find metastable de Sitter (dS) minima of the potential for moduli obtained from a compactification on a product of two nil three-manifolds (which have negative scalar curvature) combined with orientifolds, branes, fractional Chern-Simons forms, and fluxes. As a discrete quantum number is taken large, the curvature, field strengths, inverse volume, and four-dimensional string coupling become parametrically small, and the de Sitter Hubble scale can be tuned parametrically smaller than the scales of the moduli, Kaluza Klein (KK), and winding mode masses. A subtle point in the construction is that although the curvature remains consistently weak, the circle fibers of the nilmanifolds become very small in this limit (though this is avoided in illustrative solutions at modest values of the parameters). In the simplest version of the construction, the heaviest moduli masses are parametrically of the same order as the lightest KK and winding masses. However, we provide a method for separating these marginally overlapping scales, and more generally the underlying supersymmetry of the model protects against large corrections to the low-energy moduli potential

  15. Critical phenomena of regular black holes in anti-de Sitter space-time

    Energy Technology Data Exchange (ETDEWEB)

    Fan, Zhong-Ying [Peking University, Center for High Energy Physics, Beijing (China)

    2017-04-15

    In General Relativity, addressing coupling to a non-linear electromagnetic field, together with a negative cosmological constant, we obtain the general static spherical symmetric black hole solution with magnetic charges, which is asymptotic to anti-de Sitter (AdS) space-times. In particular, for a degenerate case the solution becomes a Hayward-AdS black hole, which is regular everywhere in the full space-time. The existence of such a regular black hole solution preserves the weak energy condition, while the strong energy condition is violated. We then derive the first law and the Smarr formula of the black hole solution. We further discuss its thermodynamic properties and study the critical phenomena in the extended phase space where the cosmological constant is treated as a thermodynamic variable as well as the parameter associated with the non-linear electrodynamics. We obtain many interesting results such as: the Maxwell equal area law in the P-V (or S-T) diagram is violated and consequently the critical point (T{sub *},P{sub *}) of the first order small-large black hole transition does not coincide with the inflection point (T{sub c},P{sub c}) of the isotherms; the Clapeyron equation describing the coexistence curve of the Van der Waals (vdW) fluid is no longer valid; the heat capacity at constant pressure is finite at the critical point; the various exponents near the critical point are also different from those of the vdW fluid. (orig.)

  16. Toward de Sitter space from ten dimensions

    Science.gov (United States)

    Moritz, Jakob; Retolaza, Ander; Westphal, Alexander

    2018-02-01

    Using a 10D lift of nonperturbative volume stabilization in type IIB string theory, we study the limitations for obtaining de Sitter vacua. Based on this we find that the simplest Kachru, Kallosh, Linde, and Trivedi vacua with a single Kähler modulus stabilized by a gaugino condensate cannot be uplifted to de Sitter. Rather, the uplift flattens out due to stronger backreaction on the volume modulus than has previously been anticipated, resulting in vacua which are metastable and supersymmetry breaking, but that are always anti-de Sitter (AdS). However, we also show that setups such as racetrack stabilization can avoid this issue. In these models it is possible to obtain supersymmetric AdS vacua with a cosmological constant that can be tuned to zero while retaining finite moduli stabilization. In this regime, it seems that de Sitter uplifts are possible with negligible backreaction on the internal volume. We exhibit this behavior also from the 10D perspective.

  17. Spacetime Singularity Resolution by M-Theory Fivebranes: Calibrated Geometry, Anti-de Sitter Solutions and Special Holonomy Metrics

    Science.gov (United States)

    Conamhna, Oisín A. P. Mac

    2008-12-01

    The supergravity description of various configurations of supersymmetric M-fivebranes wrapped on calibrated cycles of special holonomy manifolds is studied. The description is provided by solutions of eleven-dimensional supergravity which interpolate smoothly between a special holonomy manifold and an event horizon with Anti-de Sitter geometry. For known examples of Anti-de Sitter solutions, the associated special holonomy metric is derived. One explicit Anti-de Sitter solution of M-theory is so treated for fivebranes wrapping each of the following cycles: Kähler cycles in Calabi-Yau two, three- and four-folds; special lagrangian cycles in three- and four-folds; associative three- and co-associative four-cycles in G 2 manifolds; complex lagrangian four-cycles in Sp(2) manifolds; and Cayley four-cycles in Spin(7) manifolds. In each case, the associated special holonomy metric is singular, and is a hyperbolic analogue of a known metric. The analogous known metrics are respectively: Eguchi-Hanson, the resolved conifold and the four-fold resolved conifold; the deformed conifold, and the Stenzel four-fold metric; the Bryant-Salamon-Gibbons-Page-Pope G 2 metrics on an {mathbb{R}^4} bundle over S 3, and an {mathbb{R}^3} bundle over S 4 or {mathbb{CP}^2} ; the Calabi hyper-Kähler metric on {T^*mathbb{CP}^2} ; and the Bryant-Salamon-Gibbons-Page-Pope Spin(7) metric on an {mathbb{R}^4} bundle over S 4. By the AdS/CFT correspondence, a conformal field theory is associated to each of the new singular special holonomy metrics, and defines the quantum gravitational physics of the resolution of their singularities.

  18. The zero mass limit of Kerr and Kerr-(anti-)de-Sitter space-times: exact solutions and wormholes

    Science.gov (United States)

    Birkandan, T.; Hortaçsu, M.

    2018-03-01

    Heun-type exact solutions emerge for both the radial and the angular equations for the case of a scalar particle coupled to the zero mass limit of both the Kerr and Kerr-(anti)de-Sitter spacetime. Since any type D metric has Heun-type solutions, it is interesting that this property is retained in the zero mass case. This work further refutes the claims that M going to zero limit of the Kerr metric is both locally and globally the same as the Minkowski metric.

  19. A detailed analytic study of the asymptotic quasinormal modes of Schwarzschild-anti de Sitter black holes

    International Nuclear Information System (INIS)

    Daghigh, Ramin G; Green, Michael D

    2009-01-01

    We analyze analytically the asymptotic regions of the quasinormal mode frequency spectra with infinitely large overtone numbers for D-dimensional Schwarzschild black holes in anti de Sitter spacetimes. In this limit, we confirm the analytic results obtained previously in the literature using different methods. In addition, we show that in certain spacetime dimensions these techniques imply the existence of other regions of the asymptotic quasinormal mode frequency spectrum which have not previously appeared in the literature. For large black holes, some of these modes have a damping rate of 1.2T H , where T H is the Hawking temperature. This is less than the damping rate of the lowest overtone quasinormal mode calculated by other authors. It is not completely clear whether these modes actually exist or are an artifact of an unknown flaw in the analytic techniques being used. We discuss the possibility of the existence of these modes and explore some of the consequences. We also examine the possible connection between the asymptotic quasinormal modes of Schwarzschild-anti de Sitter black holes and the quantum level spacing of their horizon area spectrum.

  20. Graviatoms with de Sitter Interior

    Directory of Open Access Journals (Sweden)

    Irina Dymnikova

    2013-01-01

    Full Text Available We present a graviatom with de Sitter interior as a new candidate to atomic dark matter generically related to a vacuum dark energy through its de Sitter vacuum interior. It is a gravitationally bound quantum system consisting of a nucleus represented by a regular primordial black hole (RPBH, its remnant or gravitational vacuum soliton G-lump, and a charged particle. We estimate probability of formation of RPBHs and G-lumps in the early Universe and evaluate energy spectrum and electromagnetic radiation of graviatom which can in principle bear information about a fundamental symmetry scale responsible for de Sitter interior and serve as its observational signatures.

  1. Group theoretical approach to quantum fields in de Sitter space II. The complementary and discrete series

    International Nuclear Information System (INIS)

    Joung, Euihun; Mourad, Jihad; Parentani, Renaud

    2007-01-01

    We use an algebraic approach based on representations of de Sitter group to construct covariant quantum fields in arbitrary dimensions. We study the complementary and the discrete series which correspond to light and massless fields and which lead new feature with respect to the massive principal series we previously studied (hep-th/0606119). When considering the complementary series, we make use of a non-trivial scalar product in order to get local expressions in the position representation. Based on these, we construct a family of covariant canonical fields parametrized by SU(1, 1)/U(1). Each of these correspond to the dS invariant alpha-vacua. The behavior of the modes at asymptotic times brings another difficulty as it is incompatible with the usual definition of the in and out vacua. We propose a generalized notion of these vacua which reduces to the usual conformal vacuum in the conformally massless limit. When considering the massless discrete series we find that no covariant field obeys the canonical commutation relations. To further analyze this singular case, we consider the massless limit of the complementary scalar fields we previously found. We obtain canonical fields with a deformed representation by zero modes. The zero modes have a dS invariant vacuum with singular norm. We propose a regularization by a compactification of the scalar field and a dS invariant definition of the vertex operators. The resulting two-point functions are dS invariant and have a universal logarithmic infrared divergence

  2. Ringing in de Sitter spacetime

    Directory of Open Access Journals (Sweden)

    Alex Buchel

    2018-03-01

    Full Text Available Hydrodynamics is a universal effective theory describing relaxation of quantum field theories towards equilibrium. Massive QFTs in de Sitter spacetime are never at equilibrium. We use holographic gauge theory/gravity correspondence to describe relaxation of a QFT to its Bunch–Davies vacuum — an attractor of its late-time dynamics. Specifically, we compute the analogue of the quasinormal modes describing the relaxation of a holographic toy model QFT in de Sitter.

  3. Building an explicit de Sitter

    Energy Technology Data Exchange (ETDEWEB)

    Louis, Jan [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Hamburg Univ. (Germany). Zentrum fuer Mathematische Physik; Rummel, Markus; Valandro, Roberto [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Westphal, Alexander [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany). Gruppe Theorie

    2012-11-15

    We construct an explicit example of a de Sitter vacuum in type IIB string theory that realizes the proposal of Kaehler uplifting. As the large volume limit in this method depends on the rank of the largest condensing gauge group we carry out a scan of gauge group ranks over the Kreuzer-Skarke set of toric Calabi-Yau threefolds. We find large numbers of models with the largest gauge group factor easily exceeding a rank of one hundred. We construct a global model with Kaehler uplifting on a two-parameter model on CP{sup 4}{sub 11169}, by an explicit analysis from both the type IIB and F-theory point of view. The explicitness of the construction lies in the realization of a D7 brane configuration, gauge flux and RR and NS flux choices, such that all known consistency conditions are met and the geometric moduli are stabilized in a metastable de Sitter vacuum with spontaneous GUT scale supersymmetry breaking driven by an F-term of the Kaehler moduli.

  4. Finite upper bound for the Hawking decay time of an arbitrarily large black hole in anti-de Sitter spacetime

    Science.gov (United States)

    Page, Don N.

    2018-01-01

    In an asymptotically flat spacetime of dimension d >3 and with the Newtonian gravitational constant G , a spherical black hole of initial horizon radius rh and mass M ˜rhd -3/G has a total decay time to Hawking emission of td˜rhd -1/G ˜G2 /(d -3 )M(d -1 )/(d -3 ) which grows without bound as the radius rh and mass M are taken to infinity. However, in asymptotically anti-de Sitter spacetime with a length scale ℓ and with absorbing boundary conditions at infinity, the total Hawking decay time does not diverge as the mass and radius go to infinity but instead remains bounded by a time of the order of ℓd-1/G .

  5. Fermion tunnels of higher-dimensional anti-de Sitter Schwarzschild black hole and its corrected entropy

    Energy Technology Data Exchange (ETDEWEB)

    Lin Kai, E-mail: lk314159@126.co [Institute of Theoretical Physics, China West Normal University, NanChong, SiChuan 637002 (China); Yang Shuzheng, E-mail: szyangcwnu@126.co [Institute of Theoretical Physics, China West Normal University, NanChong, SiChuan 637002 (China)

    2009-10-12

    Applying the method beyond semiclassical approximation, fermion tunneling from higher-dimensional anti-de Sitter Schwarzschild black hole is researched. In our work, the 'tortoise' coordinate transformation is introduced to simplify Dirac equation, so that the equation proves that only the (r-t) sector is important to our research. Because we only need to study the (r-t) sector, the Dirac equation is decomposed into several pairs of equations spontaneously, and we then prove the components of wave functions are proportional to each other in every pair of equations. Therefore, the suitable action forms of the wave functions are obtained, and finally the correctional Hawking temperature and entropy can be determined via the method beyond semiclassical approximation.

  6. Quasilocal thermodynamics of Kerr and Kerr--anti-de Sitter spacetimes and the AdS/CFT correspondence

    International Nuclear Information System (INIS)

    Dehghani, M. H.; Mann, R. B.

    2001-01-01

    We consider the quasilocal thermodynamics of rotating black holes in asymptotically flat and asymptotically anti--de Sitter (AdS) spacetimes. Using the minimal number of intrinsic boundary counterterms inspired by the AdS/conformal field theory correspondence, we find that we are able to carry out an analysis of the thermodynamics of these black holes for virtually all possible values of the rotation parameter and cosmological constant that leave the quasilocal boundary well defined, going well beyond what is possible with background subtraction methods. Specifically, we compute the quasilocal energy E and angular momentum J for arbitrary values of the rotation, mass, and cosmological constant parameters for the (3+1)-dimensional Kerr, Kerr-AdS black holes, and (2+1)-dimensional Banados-Teitelboim-Zannelli (BTZ) black hole. We perform a quasilocal stability analysis and find phase behavior that is commensurate with previous analyses carried out at infinity

  7. Applications of gauge/gravity dualities with charged Anti-de Sitter black holes

    Energy Technology Data Exchange (ETDEWEB)

    Grass, Viviane Theresa

    2010-05-17

    In this thesis, we deal with different applications of the Anti-de Sitter/Conformal Field Theory (AdS/CFT) correspondence. The AdS/CFT correspondence, which is also more generally referred to as gauge/gravity duality, is a conjectured duality in superstring theory between strongly-coupled four-dimensional N=4 superconformal Yang-Mills theory and weakly-coupled type IIB string theory in five-dimensional AdS spacetime. This duality provides a powerful method to investigate strongly-coupled low-energy systems in four dimensions by substitutionally carrying out calculations in five-dimensional weakly-coupled supergravity. In this work, we use the AdS/CFT correspondence to explore three different strongly-coupled systems, namely a brane world accommodating a strongly-coupled field theory, a strongly-coupled fluid on a three-sphere and a strongly-coupled p-wave superfluid. In all these cases, the dual supergravity descriptions involve charged AdS black holes. The first system studied here is a Randall-Sundrum brane world moving in the background of a five-dimensional non-extremal black hole of N=2 gauged supergravity. The equations of motion of the brane are found to be equal to the Friedmann-Robertson-Walker (FRW) equations for a closed universe. The closed brane universe has special thermodynamic properties. The energy of the brane field theory exhibits a subextensive Casimir contribution, and the entropy can be expressed as a Cardy-Verlinde-type formula. We show that the equations for both quantities can take forms that strongly resemble the two FRW equations. At the horizon of the black hole, these two sets of equations are shown to even merge with each other which might suggest the existence of a common underlying theory. In addition, as a by-product result, the non-extremal black hole solutions considered here are found to admit an alternative description in terms of first-order flow equations similar to those which are well-known from the attractor mechanism of

  8. Krein Spaces in de Sitter Quantum Theories

    Czech Academy of Sciences Publication Activity Database

    Gazeau, J.P.; Siegl, Petr; Youssef, A.

    2010-01-01

    Roč. 6, - (2010), 011/1-011/23 ISSN 1815-0659 Institutional research plan: CEZ:AV0Z10480505 Keywords : de Sitter group * undecomposable representations * Krein spaces Subject RIV: BE - Theoretical Physics Impact factor: 0.856, year: 2010

  9. Quasinormal modes of a massless charged scalar field on a small Reissner-Nordstroem-anti-de Sitter black hole

    International Nuclear Information System (INIS)

    Uchikata, Nami; Yoshida, Shijun

    2011-01-01

    We investigate quasinormal modes of a massless charged scalar field on a small Reissner-Nordstroem-anti-de Sitter (RN-AdS) black hole both with analytical and numerical approaches. In the analytical approach, by using the small black hole approximation (r + + /L→0, where r + and L stand for the black hole event horizon radius and the AdS scale, respectively. We then show that the small RN-AdS black hole is unstable if its quasinormal modes satisfy the superradiance condition and that the instability condition of the RN-AdS black hole in the limit of r + /L→0 is given by Q>(3/eL)Q c , where Q, Q c , and e are the charge of the black hole, the critical (maximum) charge of the black hole, and the charge of the scalar field, respectively. In the numerical approach, we calculate the quasinormal modes for the small RN-AdS black holes with r + + =0.2L, 0.1L, and 0.01L become unstable against scalar perturbations with eL=4 when the charge of the black hole satisfies Q > or approx. 0.8Q c , 0.78Q c , and 0.76Q c , respectively.

  10. Superradiant instability of D-dimensional Reissner-Nordström-anti-de Sitter black hole mirror system

    Science.gov (United States)

    Huang, Yang; Liu, Dao-Jun; Li, Xin-Zhou

    In this paper, a detailed analysis for superradiant stability of the system composed by a D-dimensional Reissner-Nordström-anti-de Sitter (RN-AdS) black hole and a reflecting mirror under charged scalar perturbations are presented in the linear regime. It is found that the stability of the system is heavily affected by the mirror radius as well as the mass of the scalar perturbation, AdS radius and the dimension of spacetime. In a higher dimensional spacetime, the degree of instability of the superradiant modes will be severely weakened. Nevertheless, the degree of instability can be magnified significantly by choosing a suitable value of the mirror radius. Remarkably, when the mirror radius is smaller than a threshold value the system becomes stable. We also find that massive charged scalar fields cannot trigger the instabilities in the background of D-dimensional asymptotically flat RN black hole. For a given scalar charge, a small RN-AdS black hole can be superradiantly unstable, while a large one may be always stable under charged scalar field with or without a reflecting mirror. We also show that these results can be easily expounded and understood with the help of factorized potential analysis.

  11. Phase structure of the Born-Infeld-anti-de Sitter black holes probed by non-local observables

    Energy Technology Data Exchange (ETDEWEB)

    Zeng, Xiao-Xiong [Chongqing Jiaotong University, School of Material Science and Engineering, Chongqing (China); Chinese Academy of Sciences, Institute of Theoretical Physics, Beijing (China); Liu, Xian-Ming [Center for Theoretical Physics, Massachusetts Institute of Technology, Cambridge, MA (United States); Hubei University for Nationalities, Center for Theoretical Physics, School of Sciences, Enshi, Hubei (China); Li, Li-Fang [Chinese Academy of Sciences, State Key Laboratory of Space Weather, Center for Space Science and Applied Research, Beijing (China)

    2016-11-15

    With the non-local observables such as two point correlation function and holographic entanglement entropy, we probe the phase structure of the Born-Infeld-anti-de Sitter black holes. For the case bQ > 0.5, where b is the Born-Infeld parameter and Q is the charge of the black hole, the phase structure is found to be similar to that of the Van der Waals phase transition, namely the black hole undergoes a first order phase transition and a second order phase transition before it reaches a stable phase. While for the case bQ < 0.5, a new phase branch emerges besides the Van der Waals phase transition. For the first order phase transition, the equal area law is checked, and for the second order phase transition, the critical exponent of the heat capacity is obtained. All these results are found to be the same as that observed in the entropy-temperature plane. (orig.)

  12. Non-linear realization of supersymmetry in de Sitter space

    CERN Document Server

    Zumino, B

    1977-01-01

    The author derives the non-linear transformation law and the non- linear Lagrangian for a Goldstone spinor corresponding to spontaneous breaking of global supersymmetry in a de Sitter space with O(3,2) invariance (anti de Sitter space). With a suitable choice of the Goldstone spinor field the Lagrangian agrees with the form suggested by the coupling to supergravity. The construction is also valid for the case of extended supersymmetry. (21 refs).

  13. Noncommutative de Sitter and FRW spaces

    International Nuclear Information System (INIS)

    Burić, Maja; Madore, John

    2015-01-01

    Several versions of fuzzy four-dimensional de Sitter space are constructed using the noncommutative frame formalism. Although all noncommutative spacetimes which are found have commutative de Sitter metric as a classical limit, the algebras and the differential calculi which define them have many differences, which we derive and discuss

  14. Noncommutative de Sitter and FRW spaces

    Energy Technology Data Exchange (ETDEWEB)

    Burić, Maja, E-mail: majab@ipb.ac.rs [Faculty of Physics, University of Belgrade, P.O. Box 44, 11001, Belgrade (Serbia); Madore, John, E-mail: madore@th.u-psud.fr [Laboratoire de Physique Théorique, 91405, Orsay (France)

    2015-10-24

    Several versions of fuzzy four-dimensional de Sitter space are constructed using the noncommutative frame formalism. Although all noncommutative spacetimes which are found have commutative de Sitter metric as a classical limit, the algebras and the differential calculi which define them have many differences, which we derive and discuss.

  15. ''Massless'' vector field in de Sitter universe

    International Nuclear Information System (INIS)

    Garidi, T.; Gazeau, J.-P.; Rouhani, S.; Takook, M. V.

    2008-01-01

    We proceed to the quantization of the massless vector field in the de Sitter (dS) space. This work is the natural continuation of a previous article devoted to the quantization of the dS massive vector field [J. P. Gazeau and M. V. Takook, J. Math. Phys. 41, 5920 (2000); T. Garidi et al., ibid. 43, 6379 (2002).] The term ''massless'' is used by reference to conformal invariance and propagation on the dS lightcone whereas ''massive'' refers to those dS fields which unambiguously contract to Minkowskian massive fields at zero curvature. Due to the combined occurrences of gauge invariance and indefinite metric, the covariant quantization of the massless vector field requires an indecomposable representation of the de Sitter group. We work with the gauge fixing corresponding to the simplest Gupta-Bleuler structure. The field operator is defined with the help of coordinate-independent de Sitter waves (the modes). The latter are simple to manipulate and most adapted to group theoretical approaches. The physical states characterized by the divergencelessness condition are, for instance, easy to identify. The whole construction is based on analyticity requirements in the complexified pseudo-Riemannian manifold for the modes and the two-point function

  16. ``Massless'' vector field in de Sitter universe

    Science.gov (United States)

    Garidi, T.; Gazeau, J.-P.; Rouhani, S.; Takook, M. V.

    2008-03-01

    We proceed to the quantization of the massless vector field in the de Sitter (dS) space. This work is the natural continuation of a previous article devoted to the quantization of the dS massive vector field [J. P. Gazeau and M. V. Takook, J. Math. Phys. 41, 5920 (2000); T. Garidi et al., ibid. 43, 6379 (2002).] The term ``massless'' is used by reference to conformal invariance and propagation on the dS lightcone whereas ``massive'' refers to those dS fields which unambiguously contract to Minkowskian massive fields at zero curvature. Due to the combined occurrences of gauge invariance and indefinite metric, the covariant quantization of the massless vector field requires an indecomposable representation of the de Sitter group. We work with the gauge fixing corresponding to the simplest Gupta-Bleuler structure. The field operator is defined with the help of coordinate-independent de Sitter waves (the modes). The latter are simple to manipulate and most adapted to group theoretical approaches. The physical states characterized by the divergencelessness condition are, for instance, easy to identify. The whole construction is based on analyticity requirements in the complexified pseudo-Riemannian manifold for the modes and the two-point function.

  17. M-theory and stringy corrections to anti-de Sitter black holes and conformal field theories

    International Nuclear Information System (INIS)

    Caldarelli, Marco M.; Klemm, Dietmar

    1999-01-01

    We consider black holes in anti-de Sitter space AdS p+2 (p = 2, 3, 5), which have hyperbolic, flat or spherical event horizons. The O(α' 3 ) corrections (or the leading corrections in powers of the eleven-dimensional Planck length, in the case of M-theory compactifications) to the black hole metrics are computed for the various topologies and dimensions. We investigate the consequences of the stringy or M-theory corrections for the black hole thermodynamics. In particular, we show the emergence of a stable branch of small spherical black holes. Surprisingly, for any of the considered dimension and topologies, the corrected thermodynamical quantities turn out to coincide with those calculated within a simplified approach, which uses only the unperturbed metric. We obtain the corrected Hawking-Page transition temperature for black holes with spherical horizons, and show that for p = 3 this phase transition disappears at a value of α' considerably smaller than that estimated previously by Gao and Li. Using the AdS/CFT correspondence, we determine the S 1 x S 3 N = 4 SYM phase diagram for sufficiently large 't Hooft coupling, and show that the critical point at which the Hawking-Page transition disappears (the correspondence point of Horowitz-Polchinski), occurs at g 2 YM N ∼ 20.5. The d = 4 and d = 7 black hole phase diagrams are also determined, and connection is made with the corresponding boundary CFTs. Finally, for flat and hyperbolic horizons, we show that the leading stringy or M-theory corrections do not give rise to any phase transition. However, if the horizon is compactified to a torus T p or to a quotient of hyperbolic space, H p /Γ, the appearance of light winding modes around non-contractible cycles signal new phase transitions, which in the toroidal case have previously been discussed by Barbon et al. We comment on these phase transitions for SYM on H p /Γ and on T p , when the moduli of the torus are taken into account

  18. On a Canonical Quantization of 3D Anti de Sitter Pure Gravity

    CERN Document Server

    Kim, Jihun

    2015-10-14

    We perform a canonical quantization of pure gravity on AdS3 using as a technical tool its equivalence at the classical level with a Chern-Simons theory with gauge group SL(2,R)xSL(2,R). We first quantize the theory canonically on an asymptotically AdS space --which is topologically the real line times a Riemann surface with one connected boundary. Using the "constrain first" approach we reduce canonical quantization to quantization of orbits of the Virasoro group and Kaehler quantization of Teichmuller space. After explicitly computing the Kaehler form for the torus with one boundary component and after extending that result to higher genus, we recover known results, such as that wave functions of SL(2,R) Chern-Simons theory are conformal blocks. We find new restrictions on the Hilbert space of pure gravity by imposing invariance under large diffeomorphisms and normalizability of the wave function. The Hilbert space of pure gravity is shown to be the target space of Conformal Field Theories with continuous sp...

  19. On a canonical quantization of 3D Anti de Sitter pure gravity

    Science.gov (United States)

    Kim, Jihun; Porrati, Massimo

    2015-10-01

    We perform a canonical quantization of pure gravity on AdS 3 using as a technical tool its equivalence at the classical level with a Chern-Simons theory with gauge group SL(2,{R})× SL(2,{R}) . We first quantize the theory canonically on an asymptotically AdS space -which is topologically the real line times a Riemann surface with one connected boundary. Using the "constrain first" approach we reduce canonical quantization to quantization of orbits of the Virasoro group and Kähler quantization of Teichmüller space. After explicitly computing the Kähler form for the torus with one boundary component and after extending that result to higher genus, we recover known results, such as that wave functions of SL(2,{R}) Chern-Simons theory are conformal blocks. We find new restrictions on the Hilbert space of pure gravity by imposing invariance under large diffeomorphisms and normalizability of the wave function. The Hilbert space of pure gravity is shown to be the target space of Conformal Field Theories with continuous spectrum and a lower bound on operator dimensions. A projection defined by topology changing amplitudes in Euclidean gravity is proposed. It defines an invariant subspace that allows for a dual interpretation in terms of a Liouville CFT. Problems and features of the CFT dual are assessed and a new definition of the Hilbert space, exempt from those problems, is proposed in the case of highly-curved AdS 3.

  20. On a canonical quantization of 3D Anti de Sitter pure gravity

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jihun [Center for Cosmology and Particle Physics, Department of Physics,New York University, 4 Washington Place, New York, NY 10003 (United States); Porrati, Massimo [Center for Cosmology and Particle Physics, Department of Physics,New York University, 4 Washington Place, New York, NY 10003 (United States); CERN PH-TH, CH 1211,Geneva 23 (Switzerland)

    2015-10-14

    We perform a canonical quantization of pure gravity on AdS{sub 3} using as a technical tool its equivalence at the classical level with a Chern-Simons theory with gauge group SL(2,ℝ)×SL(2,ℝ). We first quantize the theory canonically on an asymptotically AdS space –which is topologically the real line times a Riemann surface with one connected boundary. Using the “constrain first” approach we reduce canonical quantization to quantization of orbits of the Virasoro group and Kähler quantization of Teichmüller space. After explicitly computing the Kähler form for the torus with one boundary component and after extending that result to higher genus, we recover known results, such as that wave functions of SL(2,ℝ) Chern-Simons theory are conformal blocks. We find new restrictions on the Hilbert space of pure gravity by imposing invariance under large diffeomorphisms and normalizability of the wave function. The Hilbert space of pure gravity is shown to be the target space of Conformal Field Theories with continuous spectrum and a lower bound on operator dimensions. A projection defined by topology changing amplitudes in Euclidean gravity is proposed. It defines an invariant subspace that allows for a dual interpretation in terms of a Liouville CFT. Problems and features of the CFT dual are assessed and a new definition of the Hilbert space, exempt from those problems, is proposed in the case of highly-curved AdS{sub 3}.

  1. The gravitational exclusion principle and null states in anti-de Sitter space

    Energy Technology Data Exchange (ETDEWEB)

    Castro, Alejandra; Maloney, Alexander [Department of Physics, McGill University, Montreal, QC (Canada); Hartman, Thomas [School of Natural Sciences, Institute for Advanced Study, Princeton, NJ (United States)

    2011-10-07

    The holographic principle implies a vast reduction in the number of degrees of freedom of quantum gravity. This idea can be made precise in AdS{sub 3}, where the the stringy or gravitational exclusion principle asserts that certain perturbative excitations are not present in the exact quantum spectrum. We show that this effect is visible directly in the bulk gravity theory: the norm of the offending linearized state is zero or negative. When the norm is negative, the theory is signalling its own breakdown as an effective field theory; this provides a perturbative bulk explanation for the stringy exclusion principle. When the norm vanishes the bulk state is null rather than physical. This implies that certain non-trivial diffeomorphisms must be regarded as gauge symmetries rather than spectrum-generating elements of the asymptotic symmetry group. This leads to subtle effects in the computation of one-loop determinants for Einstein gravity, higher spin theories and topologically massive gravity in AdS{sub 3}. In particular, heat kernel methods do not capture the correct spectrum of a theory with null states. Communicated by S Ross

  2. De Sitter structured connection and gauge translations

    International Nuclear Information System (INIS)

    Aldinger, R.R.

    1986-01-01

    A local gauge field description of space-time is discussed using fiber bundle techniques as a theoretical framework. The basic idea is to endow ordinary Minkowski space, M 4 , with a somewhat richer structure than that implied by relativity by attaching to each position x epsilon M 4 a copy of a four-dimensional micro-space of constant curvature characterized by an elementary subatomic length parameter R of the order of a Fermi, thus allowing for additional internal degrees-of-freedom. Therefore, two sets of variables are introduced: (i) the usual space-time variables x which determine an element of M 4 and (ii) a second set zeta which are elements of an internal space F (which is identified with the fiber of a bundle constructed over M 4 ). Consequently, they consider a fiber bundle E(B,F,G,P) constructed over a four-dimensional base manifold B (which is taken to be the usual Minkowski space, M 4 ), possessing a four-dimensional fiber F, and associated with the principal bundle P=P(B,G) (on which the connection is defined). The structural (gauge) group G of the bundle plays the role of an internal symmetry group and therefore determines the possible motions of the internal degrees-of-freedom belonging to the fibers. As fiber they choose a four-dimensional pseudo-Riemannian space of constant (negative) curvature R:F = SO(4,1)/SO(3,1) (i.e., a de Sitter space) which contains, at each point of contact with base manifold M 4 , a tangent space which is isomorphic to Minkowski space. The structural group of the bundle is a de Sitter SO(4,1) which contains a Lorentz subgroup and a four parameter family of transformations (the de Sitter boosts), which in the limit R → ∞ corresponding to translations. 10 references

  3. Quantum break-time of de Sitter

    Science.gov (United States)

    Dvali, Gia; Gómez, César; Zell, Sebastian

    2017-06-01

    The quantum break-time of a system is the time-scale after which its true quantum evolution departs from the classical mean field evolution. For capturing it, a quantum resolution of the classical background—e.g., in terms of a coherent state—is required. In this paper, we first consider a simple scalar model with anharmonic oscillations and derive its quantum break-time. Next, following [1], we apply these ideas to de Sitter space. We formulate a simple model of a spin-2 field, which for some time reproduces the de Sitter metric and simultaneously allows for its well-defined representation as quantum coherent state of gravitons. The mean occupation number N of background gravitons turns out to be equal to the de Sitter horizon area in Planck units, while their frequency is given by the de Sitter Hubble parameter. In the semi-classical limit, we show that the model reproduces all the known properties of de Sitter, such as the redshift of probe particles and thermal Gibbons-Hawking radiation, all in the language of quantum S-matrix scatterings and decays of coherent state gravitons. Most importantly, this framework allows to capture the 1/N-effects to which the usual semi-classical treatment is blind. They violate the de Sitter symmetry and lead to a finite quantum break-time of the de Sitter state equal to the de Sitter radius times N. We also point out that the quantum-break time is inversely proportional to the number of particle species in the theory. Thus, the quantum break-time imposes the following consistency condition: older and species-richer universes must have smaller cosmological constants. For the maximal, phenomenologically acceptable number of species, the observed cosmological constant would saturate this bound if our Universe were 10100 years old in its entire classical history.

  4. Gravitational energy, momentum and angular momentum of Schwarzschild Anti-de Sitter space-times in the teleparallel equivalent of general relativity

    Science.gov (United States)

    Nashed, Gamal G. L.

    2011-10-01

    We give a class of spherically symmetric-Anti de Sitter (Ads), exact solution in the teleparallel equivalent of general relativity (TEGR). The solution depends on an arbitrary function {F}(R) and reproduce the metric of Schwarzschild Ads space-time. In the context of the Hamiltonian formulation of the TEGR we compute the gravitational energy of this class. The calculation is carried out by means of an expression for the energy of the gravitational field that naturally arises from the integral form of the constraint equations of the formalism. We show that the form of the energy depends on the arbitrary function. We make a constrain on this arbitrary function to give the correct form of energy.

  5. Di-jet conical correlations associated with heavy quark jets in anti-de sitter space/conformal field theory correspondence.

    Science.gov (United States)

    Noronha, Jorge; Gyulassy, Miklos; Torrieri, Giorgio

    2009-03-13

    We show that far zone Mach and diffusion wake "holograms" produced by supersonic strings in anti-de Sitter space/conformal field theory (AdS/CFT) correspondence do not lead to observable conical angular correlations in the strict N_{c}-->infinity supergravity limit if Cooper-Frye hadronization is assumed. However, a special nonequilibrium "neck" zone near the jet is shown to produce an apparent sonic boom azimuthal angle distribution that is roughly independent of the heavy quark's velocity. Our results indicate that a measurement of the dependence of the away-side correlations on the velocity of associated identified heavy quark jets at the BNL Relativistic Heavy Ion Collider and CERN LHC will provide a direct test of the nonperturbative dynamics involved in the coupling between jets and the strongly coupled quark-gluon plasma implied by AdS/CFT correspondence.

  6. Inflation as de Sitter instability

    Energy Technology Data Exchange (ETDEWEB)

    Cadoni, Mariano; Franzin, Edgardo [Universita di Cagliari, Cittadella Universitaria, Dipartimento di Fisica, Monserrato (Italy); INFN, Sezione di Cagliari, Monserrato (Italy); Mignemi, Salvatore [INFN, Sezione di Cagliari, Monserrato (Italy); Universita di Cagliari, Dipartimento di Matematica e Informatica, Cagliari (Italy)

    2016-09-15

    We consider cosmological inflation generated by a scalar field slowly rolling off from a de Sitter maximum of its potential. The models belong to the class of hilltop models and represent the most general model of this kind in which the scalar potential can be written as the sum of two exponentials. The minimally coupled Einstein-scalar gravity theory obtained in this way is the cosmological version of a two-scale generalization of known holographic models, allowing for solitonic solutions interpolating between an AdS spacetime in the infrared and scaling solutions in the ultraviolet. We then investigate cosmological inflation in the slow-roll approximation. Our model reproduces correctly, for a wide range of its parameters, the most recent experimental data for the power spectrum of primordial perturbations. Moreover, it predicts inflation at energy scales of four to five orders of magnitude below the Planck scale. At the onset of inflation, the mass of the tachyonic excitation, i.e. of the inflaton, turns out to be seven to eight orders of magnitude smaller than the Planck mass. (orig.)

  7. De Sitter thin brane model

    Science.gov (United States)

    Nishi, Masato

    2016-07-01

    We discuss the large mass hierarchy problem in a braneworld model which represents our acceleratively expanding universe. The Randall-Sundrum (RS) model with one extra warped dimension added to a flat four-dimensional space-time cannot describe our expanding universe. Here, we study instead the de Sitter thin brane model. This is described by the same action as that for the RS model, but the four-dimensional space-time on the branes is dS_4. We study the model for both the cases of positive five-dimensional cosmological constant Λ_5 and a negative one. In the positive Λ_5 case, the four-dimensional large hierarchy necessitates a five-dimensional large hierarchy, and we cannot get a natural explanation. On the other hand, in the negative Λ_5 case, the large hierarchy is naturally realized in the five-dimensional theory in the same manner as in the RS model. Moreover, another large hierarchy between the Hubble parameter and the Planck scale is realized by the O(10^2) hierarchy of the five-dimensional quantities. Finally, we find that the lightest mass of the massive Kaluza-Klein modes and the intervals of the mass spectrum are of order 10^2 GeV, which are the same as in the RS case and do not depend on the value of the Hubble parameter.

  8. Density fluctuations in the de Sitter universe

    International Nuclear Information System (INIS)

    Banerjee, N.; Mallik, S.

    1991-01-01

    The de Sitter space-time appears to be the most widely chosen manifold to study quantum field theories on curved space-time. The reason is, of course, its high symmetry and the related fact that the mode functions can be obtained exactly in terms of known functions. Thus the different problems of quantization on curved space-time, like the non-uniqueness of the vacuum, regularization and renormalization of the stress tensor, have all been studied extensively in this model. The other reason of interest in the de Sitter geometry is related to the inflationary scenario of the early universe. For a brief period, the energy density of the false (symmetric) vacuum may dominate the total energy density, giving rise to de Sitter space-time. The resulting inflation may solve a number of outstanding problems of cosmology and particle physics. The properties of a Higgs-type scalar field theory is of central importance in the investigation of such a scenario. In this paper, a scalar Higgs field theory in de Sitter space-time has been investigated using the real time formulation of Semenoff and Weiss. The authors calculate the two-point function at late times and use it to obtain a general expression for the amplitude of fluctuation in energy density on scales which come out of the de Sitter horizon

  9. Towards de Sitter from 10D

    International Nuclear Information System (INIS)

    Moritz, Jakob; Retaloza, Ander; Westphal, Alexander

    2017-07-01

    Using a 10D lift of non-perturbative volume stabilization in type IIB string theory we study the limitations for obtaining de Sitter vacua. Based on this we find that the simplest KKLT vacua with a single Kahler modulus stabilized by a gaugino condensate cannot be uplifted to de Sitter. Rather, the uplift flattens out due to stronger backreaction on the volume modulus than has previously been anticipated, resulting in vacua which are meta-stable and SUSY breaking, but that are always AdS. However, we also show that setups such as racetrack stabilization can avoid this issue. In these models it is possible to obtain supersymmetric AdS vacua with a cosmological constant that can be tuned to zero while retaining finite moduli stabilization. In this regime, it seems that de Sitter uplifts are possible with negligible backreaction on the internal volume. We exhibit this behavior also from the 10D perspective.

  10. Decay of the de Sitter vacuum

    Science.gov (United States)

    Anderson, Paul R.; Mottola, Emil; Sanders, Dillon H.

    2018-03-01

    The decay rate of the Bunch-Davies state of a massive scalar field in the expanding flat spatial sections of de Sitter space is determined by an analysis of the particle pair creation process in real time. The Feynman definition of particle and antiparticle Fourier mode solutions of the scalar wave equation and their adiabatic phase analytically continued to the complexified time domain show conclusively that the Bunch-Davies state is not the vacuum state at late times. The closely analogous creation of charged particle pairs in a uniform electric field is reviewed and Schwinger's result for the vacuum decay rate is recovered by this same real time analysis. The vacuum decay rate in each case is also calculated by switching the background field on adiabatically, allowing it to act for a very long time, and then adiabatically switching it off again. In both the uniform electric field and de Sitter cases, the particles created while the field is switched on are verified to be real, in the sense that they persist in the final asymptotic flat zero-field region. In the de Sitter case, there is an interesting residual dependence of the rate on how the de Sitter phase is ended, indicating a greater sensitivity to spatial boundary conditions. The electric current of the created particles in the E -field case and their energy density and pressure in the de Sitter case are also computed, and the magnitude of their backreaction effects on the background field estimated. Possible consequences of the Hubble scale instability of the de Sitter vacuum for cosmology, vacuum dark energy, and the cosmological "constant" problem are discussed.

  11. Super-gauge field in de Sitter universe

    Energy Technology Data Exchange (ETDEWEB)

    Parsamehr, S.; Takook, M.V. [Islamic Azad University, Department of Physics, Science and Research Branch, Tehran (Iran, Islamic Republic of); Enayati, M. [Razi University, Department of Physics, Kermanshah (Iran, Islamic Republic of)

    2016-05-15

    The Gupta-Bleuler triplet for a vector-spinor gauge field is presented in the de Sitter ambient space formalism. The invariant space of field equation solutions is obtained with respect to an indecomposable representation of the de Sitter group. By using the general solution of the massless spin-(3)/(2) field equation, the vector-spinor quantum field operator and its corresponding Fock space is constructed. The quantum field operator can be written in terms of the vector-spinor polarization states and a quantum conformally coupled massless scalar field, which is constructed on Bunch-Davies vacuum state. The two-point function is also presented, which is de Sitter covariant and analytic. (orig.)

  12. Transforming to Lorentz gauge on de Sitter

    NARCIS (Netherlands)

    Miao, S. P.; Tsamis, N.C.; Woodard, R.P.

    2009-01-01

    We demonstrate that certain gauge fixing functionals cannot be added to the action on backgrounds such as de Sitter, in which a linearization instability is present. We also construct the field-dependent gauge transformation that carries the electromagnetic vector potential from a convenient, non-de

  13. Phase transitions in de Sitter space

    Directory of Open Access Journals (Sweden)

    Alexander Vilenkin

    1983-10-01

    Full Text Available An effective potential in de Sitter space is calculated for a model of two interacting scalar fields in one-loop approximation and in a self-consistent approximation which takes into account an infinite set of diagrams. Various approaches to renormalization in de Sitter space are discussed. The results are applied to analyze the phase transition in the Hawking-Moss version of the inflationary universe scenario. Requiring that inflation is sufficiently large, we derive constraints on the parameters of the model.

  14. Quasinormal modes in pure de Sitter spacetimes

    International Nuclear Information System (INIS)

    Du Daping; Wang Bin; Su Ruheng

    2004-01-01

    We have studied scalar perturbations as well as fermion perturbations in pure de Sitter spacetimes. For scalar perturbations we have shown that well-defined quasinormal modes in d-dimensions can exist provided that the mass of scalar field m>(d-1/2l). The quasinormal modes of fermion perturbations in three and four dimensional cases have also been investigated. We found that different from other dimensional cases, in the three dimensional pure de Sitter spacetime there is no quasinormal mode for the s-wave. This interesting difference caused by the spacial dimensions is true for both scalar and fermion perturbations

  15. Flux compactifications, gauge algebras and De Sitter

    NARCIS (Netherlands)

    Dibitetto, Giuseppe; Linares, Roman; Roest, Diederik

    2010-01-01

    The introduction of (non-)geometric fluxes allows for N = 1 moduli stabilisation in a De Sitter vacuum. The aim of this Letter is to assess to what extent this is true in N = 4 compactifications. First we identify the correct gauge algebra in terms of gauge and (non-)geometric fluxes. We then show

  16. de Sitter thermodynamics: A glimpse into nonequilibrium

    International Nuclear Information System (INIS)

    Aros, Rodrigo

    2008-01-01

    In this article it is shown that the thermodynamical evolution of a Schwarzschild de Sitter space is the evaporation of its black hole. The result is extended in higher dimensions to Lovelock theories of gravity with a single positive cosmological constant

  17. Charged black lens in de Sitter space

    Science.gov (United States)

    Tomizawa, Shinya

    2018-02-01

    We obtain a charged black lens solution in the five-dimensional Einstein-Maxwell-Chern-Simons theory with a positive cosmological constant. It is shown that the solution obtained here describes the formation of a black hole with the spatial cross section of a sphere from that of the lens space of L (n ,1 ) in five-dimensional de Sitter space.

  18. Vacuum states for gravitons field in de Sitter space

    Science.gov (United States)

    Bamba, Kazuharu; Rahbardehghan, Surena; Pejhan, Hamed

    2017-11-01

    In this paper, considering the linearized Einstein equation with a two-parameter family of linear covariant gauges in de Sitter spacetime, we examine possible vacuum states for the gravitons field with respect to invariance under the de Sitter group S O0(1 ,4 ) . Our calculations explicitly reveal that there exists no natural de Sitter-invariant vacuum state (the Euclidean or Bunch-Davies state) for the gravitons field. Indeed, on the foundation of a rigorous group-theoretical reasoning, we prove that if one insists on full covariance as well as causality for the theory, one has to give up the positivity requirement of the inner product. However, one may still look for states with as much symmetry as possible, more precisely, a restrictive version of covariance by considering the gravitons field and the associated vacuum state which are, respectively, covariant and invariant with respect to some maximal subgroup of the full de Sitter group. In this regard, we treat the S O (4 ) case and find a family of S O (4 )-invariant states. The associated S O (4 )-covariant quantum field is given, as well.

  19. Time evolutions of scalar field perturbations in D-dimensional Reissner–Nordström Anti-de Sitter black holes

    Directory of Open Access Journals (Sweden)

    Ran Li

    2016-07-01

    Full Text Available Reissner–Nordström Anti-de Sitter (RNAdS black holes are unstable against the charged scalar field perturbations due to the well-known superradiance phenomenon. We present the time domain analysis of charged scalar field perturbations in the RNAdS black hole background in general dimensions. We show that the instabilities of charged scalar field can be explicitly illustrated from the time profiles of evolving scalar field. By using the Prony method to fit the time evolution data, we confirm the mode that dominates the long time behavior of scalar field is in accordance with the quasinormal mode from the frequency domain analysis. The superradiance origin of the instability can also be demonstrated by comparing the real part of the dominant mode with the superradiant condition of charged scalar field. It is shown that all the unstable modes are superradiant, which is consistent with the analytical result in the frequency domain analysis. Furthermore, we also confirm there exists the rapid exponential growing modes in the RNAdS case, which makes the RNAdS black hole a good test ground to investigate the nonlinear evolution of superradiant instability.

  20. Quantization of a scalar field in two Poincaré patches of anti-de Sitter space and AdS/CFT

    Directory of Open Access Journals (Sweden)

    Ippei Fujisawa

    2014-09-01

    Full Text Available Two sets of modes of a massive free scalar field are quantized in a pair of Poincaré patches of Lorentzian anti-de Sitter (AdS space, AdSd+1 (d≥2. It is shown that in Poincaré coordinates (r,t,x→, the two boundaries at r=±∞ are connected. When the scalar mass m satisfies a condition 0<ν=(d2/4+(mℓ2<1, there exist two sets of mode solutions to Klein–Gordon equation, with distinct fall-off behaviors at the boundary. By using the fact that the boundaries at r=±∞ are connected, a conserved Klein–Gordon norm can be defined for these two sets of scalar modes, and these modes are canonically quantized. Energy is also conserved. A prescription within the approximation of semi-classical gravity is presented for computing two- and three-point functions of the operators in the boundary CFT, which correspond to the two fall-off behaviours of scalar field solutions.

  1. 'Massless' spin-(3)/(2) fields in the de Sitter space

    Energy Technology Data Exchange (ETDEWEB)

    Azizi, A. [Islamic Azad University, Department of Physics, Sanandaj Branch, Sanandaj (Iran, Islamic Republic of); Amiri, M. [Razi University, Department of Physics, Kermanshah (Iran, Islamic Republic of)

    2014-03-15

    In this paper, 'massless' spin-(3)/(2) fields in the de Sitter space are considered. This work is a continuation of a previous paper devoted to the quantization of the de Sitter 'massive' spin-(3)/(2) fields. Due to the appearance of gauge invariance and an indefinite metric, the covariant quantization of the 'massless' spin-(3)/(2) fields requires an indecomposable representation of the de Sitter group. The gauge fixing corresponding to the simplest Gupta-Bleuler structure is used, and a gauge invariant field is discussed. The field equation is obtained by using the Casimir operator of the de Sitter group. The solutions are written in terms of the coordinateindependent de Sitter plane waves. Finally, the generalized two-point function is calculated. (orig.)

  2. Cosmic curvature from de Sitter equilibrium cosmology.

    Science.gov (United States)

    Albrecht, Andreas

    2011-10-07

    I show that the de Sitter equilibrium cosmology generically predicts observable levels of curvature in the Universe today. The predicted value of the curvature, Ω(k), depends only on the ratio of the density of nonrelativistic matter to cosmological constant density ρ(m)(0)/ρ(Λ) and the value of the curvature from the initial bubble that starts the inflation, Ω(k)(B). The result is independent of the scale of inflation, the shape of the potential during inflation, and many other details of the cosmology. Future cosmological measurements of ρ(m)(0)/ρ(Λ) and Ω(k) will open up a window on the very beginning of our Universe and offer an opportunity to support or falsify the de Sitter equilibrium cosmology.

  3. Representing the vacuum polarization on de Sitter

    Energy Technology Data Exchange (ETDEWEB)

    Leonard, Katie E.; Woodard, Richard P. [Department of Physics, University of Florida, Gainesville, Florida 32611 (United States); Prokopec, Tomislav [Institute of Theoretical Physics (ITP) and Spinoza Institute, Utrecht University, Postbus 80195, 3508 TD Utrecht (Netherlands)

    2013-03-15

    Previous studies of the vacuum polarization on de Sitter have demonstrated that there is a simple, noncovariant representation of it in which the physics is transparent. There is also a cumbersome, covariant representation in which the physics is obscure. Despite being unwieldy, the latter form has a powerful appeal for those who are concerned about de Sitter invariance. We show that nothing is lost by employing the simple, noncovariant representation because there is a closed form procedure for converting its structure functions to those of the covariant representation. We also present a vastly improved technique for reading off the noncovariant structure functions from the primitive diagrams. And we discuss the issue of representing the vacuum polarization for a general metric background.

  4. Nonexistence of extremal de Sitter black rings

    Science.gov (United States)

    Khuri, Marcus; Woolgar, Eric

    2017-11-01

    We show that near-horizon geometries in the presence of a positive cosmological constant cannot exist with ring topology. In particular, de Sitter black rings with vanishing surface gravity do not exist. Our result relies on a known mathematical theorem which is a straightforward consequence of a type of energy condition for a modified Ricci tensor, similar to the curvature-dimension conditions for the m-Bakry-Émery-Ricci tensor.

  5. Hamiltonian thermodynamics of d-dimensional (d≥4) Reissner-Nordstroem-anti-de Sitter black holes with spherical, planar, and hyperbolic topology

    International Nuclear Information System (INIS)

    Dias, Goncalo A. S.; Lemos, Jose P. S.

    2009-01-01

    The Hamiltonian thermodynamics formalism is applied to the general d-dimensional Reissner-Nordstroem-anti-de Sitter black hole with spherical, planar, and hyperbolic horizon topology. After writing its action and performing a Legendre transformation, surface terms are added in order to guarantee a well-defined variational principle with which to obtain sensible equations of motion, and also to allow later on the thermodynamical analysis. Then a Kuchar canonical transformation is done, which changes from the metric canonical coordinates to the physical parameters coordinates. Again, a well-defined variational principle is guaranteed through boundary terms. These terms influence the falloff conditions of the variables and at the same time the form of the new Lagrange multipliers. Reduction to the true degrees of freedom is performed, which are the conserved mass and charge of the black hole. Upon quantization a Lorentzian partition function Z is written for the grand canonical ensemble, where the temperature T and the electric potential φ are fixed at infinity. After imposing Euclidean boundary conditions on the partition function, the respective effective action I * , and thus the thermodynamical partition function, is determined for any dimension d and topology k. This is a quite general action. Several previous results can be then condensed in our single general formula for the effective action I * . Phase transitions are studied for the spherical case, and it is shown that all the other topologies have no phase transitions. A parallel with the Bose-Einstein condensation can be established. Finally, the expected values of energy, charge, and entropy are determined for the black hole solution.

  6. de Sitter space as a tensor network: Cosmic no-hair, complementarity, and complexity

    Science.gov (United States)

    Bao, Ning; Cao, ChunJun; Carroll, Sean M.; Chatwin-Davies, Aidan

    2017-12-01

    We investigate the proposed connection between de Sitter spacetime and the multiscale entanglement renormalization ansatz (MERA) tensor network, and ask what can be learned via such a construction. We show that the quantum state obeys a cosmic no-hair theorem: the reduced density operator describing a causal patch of the MERA asymptotes to a fixed point of a quantum channel, just as spacetimes with a positive cosmological constant asymptote to de Sitter space. The MERA is potentially compatible with a weak form of complementarity (local physics only describes single patches at a time, but the overall Hilbert space is infinite dimensional) or, with certain specific modifications to the tensor structure, a strong form (the entire theory describes only a single patch plus its horizon, in a finite-dimensional Hilbert space). We also suggest that de Sitter evolution has an interpretation in terms of circuit complexity, as has been conjectured for anti-de Sitter space.

  7. De Sitter universes and the emerging landscape in string theory

    Indian Academy of Sciences (India)

    gravity coupled to a positive cosmological constant gives rise to an exponentially expanding solution, called the de Sitter ... Thus thinking of this question brings us to the frontiers of our understanding of string ... calculated, and those with a positive value give rise to de Sitter universes. In the rest of this article I will describe a ...

  8. Compact space-like hypersurfaces in de Sitter space

    OpenAIRE

    Jinchi Lv

    2005-01-01

    We present some integral formulas for compact space-like hypersurfaces in de Sitter space and some equivalent characterizations for totally umbilical compact space-like hypersurfaces in de Sitter space in terms of mean curvature and higher-order mean curvatures.

  9. Analytic extension of the Schwarzschild-de Sitter metric

    International Nuclear Information System (INIS)

    Bazanski, S.L.; Ferrari, V.

    1986-01-01

    In this paper, co-ordinates are derived that are regular, respectively, in the neighbourhood of the two horizons which exist in the so-called Schwarzschild-de Sitter solution known in general relativity, and it is constructed a manifold that is the analytic extension of the manifold being the domain of classical Schwarzschild-de Sitter co-ordinates

  10. Constraining de Sitter Space in String Theory.

    Science.gov (United States)

    Kutasov, David; Maxfield, Travis; Melnikov, Ilarion; Sethi, Savdeep

    2015-08-14

    We argue that the heterotic string does not have classical vacua corresponding to de Sitter space-times of dimension four or higher. The same conclusion applies to type II vacua in the absence of Ramond-Ramond fluxes. Our argument extends prior supergravity no-go results to regimes of high curvature. We discuss the interpretation of the heterotic result from the perspective of dual type II orientifold constructions. Our result suggests that the genericity arguments used in string landscape discussions should be viewed with caution.

  11. Principle of space existence and De Sitter metric

    International Nuclear Information System (INIS)

    Mal'tsev, V.K.

    1990-01-01

    The selection principle for the solutions of the Einstein equations suggested in a series of papers implies the existence of space (g ik ≠ 0) only in the presence of matter (T ik ≠0). This selection principle (principle of space existence, in the Markov terminology) implies, in the general case, the absence of the cosmological solution with the De Sitter metric. On the other hand, the De Sitter metric is necessary for describing both inflation and deflation periods of the Universe. It is shown that the De Sitter metric is also allowed by the selection principle under discussion if the metric experiences the evolution into the Friedmann metric

  12. Ghost inflation and de Sitter entropy

    Science.gov (United States)

    Jazayeri, Sadra; Mukohyama, Shinji; Saitou, Rio; Watanabe, Yota

    2016-08-01

    In the setup of ghost condensation model the generalized second law of black hole thermodynamics can be respected under a radiatively stable assumption that couplings between the field responsible for ghost condensate and matter fields such as those in the Standard Model are suppressed by the Planck scale. Since not only black holes but also cosmology are expected to play important roles towards our better understanding of gravity, we consider a cosmological setup to test the theory of ghost condensation. In particular we shall show that the de Sitter entropy bound proposed by Arkani-Hamed, et al. is satisfied if ghost inflation happened in the early epoch of our universe and if there remains a tiny positive cosmological constant in the future infinity. We then propose a notion of cosmological Page time after inflation.

  13. Fuzzy Euclidean wormholes in de Sitter space

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Pisin; Hu, Yao-Chieh; Yeom, Dong-han, E-mail: pisinchen@phys.ntu.edu.tw, E-mail: r04244003@ntu.edu.tw, E-mail: innocent.yeom@gmail.com [Leung Center for Cosmology and Particle Astrophysics, National Taiwan University, Taipei 10617, Taiwan (China)

    2017-07-01

    We investigate Euclidean wormholes in Einstein gravity with a massless scalar field in de Sitter space. Euclidean wormholes are possible due to the analytic continuation of the time as well as complexification of fields, where we need to impose the classicality after the Wick-rotation to the Lorentzian signatures. For some parameters, wormholes are preferred than Hawking-Moss instantons, and hence wormholes can be more fundamental than Hawking-Moss type instantons. Euclidean wormholes can be interpreted in three ways: (1) classical big bounce, (2) either tunneling from a small to a large universe or a creation of a collapsing and an expanding universe from nothing, and (3) either a transition from a contracting to a bouncing phase or a creation of two expanding universes from nothing. These various interpretations shed some light on challenges of singularities. In addition, these will help to understand tensions between various kinds of quantum gravity theories.

  14. A de Sitter tachyon thick braneworld

    Energy Technology Data Exchange (ETDEWEB)

    Germán, Gabriel; Herrera-Aguilar, Alfredo; Malagón-Morejón, Dagoberto [Instituto de Ciencias Físicas, Universidad Nacional Autónoma de México, Apdo. Postal 48-3, 62251, Cuernavaca, Morelos (Mexico); Mora-Luna, Refugio Rigel [Instituto de Física y Matemáticas, Universidad Michoacana de San Nicolás de Hidalgo, Edificio C-3, Ciudad Universitaria, C.P. 58040, Morelia, Michoacán (Mexico); Rocha, Roldão da, E-mail: gabriel@fis.unam.mx, E-mail: aha@fis.unam.mx, E-mail: malagon@ifm.umich.mx, E-mail: rigel@ifm.umich.mx, E-mail: roldao.rocha@ufabc.edu.br [Centro de Matemática, Computação e Cognição, Universidade Federal do ABC, Rua Santa Adélia, 166 09210-170, Santo André, SP (Brazil)

    2013-02-01

    Among the multiple 5D thick braneworld models that have been proposed in the last years, in order to address several open problems in modern physics, there is a specific one involving a tachyonic bulk scalar field. Delving into this framework, a thick braneworld with a cosmological background induced on the brane is here investigated. The respective field equations — derived from the model with a warped 5D geometry — are highly non-linear equations, admitting a non-trivial solution for the warp factor and the tachyon scalar field as well, in a de Sitter 4D cosmological background. Moreover, the non-linear tachyonic scalar field, that generates the brane in complicity with warped gravity, has the form of a kink-like configuration. Notwithstanding, the non-linear field equations restricting character does not allow one to easily find thick brane solutions with a decaying warp factor which leads to the localization of 4D gravity and other matter fields. We derive such a thick brane configuration altogether in this tachyon-gravity setup. When analyzing the spectrum of gravity fluctuations in the transverse traceless sector, the 4D gravity is shown to be localized due to the presence of a single zero mode bound state, separated by a continuum of massive Kaluza-Klein (KK) modes by a mass gap. It contrasts with previous results, where there is a KK massive bound excitation providing no clear physical interpretation. The mass gap is determined by the scale of the metric parameter H. Finally, the corrections to Newton's law in this model are computed and shown to decay exponentially. It is in full compliance to corrections reported in previous results (up to a constant factor) within similar braneworlds with induced 4D de Sitter metric, despite the fact that the warp factor and the massive modes have a different form.

  15. Kinematics of a relativistic particle with de Sitter momentum space

    Energy Technology Data Exchange (ETDEWEB)

    Arzano, Michele [Institute for Theoretical Physics and Spinoza Institute, Utrecht University, Leuvenlaan 4, Utrecht 3584 TD (Netherlands); Kowalski-Glikman, Jerzy, E-mail: marzano@uu.nl, E-mail: jkowalskiglikman@ift.uni.wroc.pl [Institute for Theoretical Physics, University of Wroclaw, Pl. Maxa Borna 9, Pl-50-204 Wroclaw (Poland)

    2011-05-21

    We discuss kinematical properties of a free relativistic particle with deformed phase space in which momentum space is given by (a submanifold of) de Sitter space. We provide a detailed derivation of the action, Hamiltonian structure and equations of motion for such a free particle. We study the action of deformed relativistic symmetries on the phase space and derive explicit formulae for the action of the deformed Poincare group. Finally we provide a discussion on parametrization of the particle worldlines stressing analogies and differences with ordinary relativistic kinematics.

  16. Area spectrum of the D-dimensional de Sitter spacetime

    International Nuclear Information System (INIS)

    Lopez-Ortega, A.

    2009-01-01

    The determination of the quantum area spectrum of a black hole horizon by means of its asymptotic quasinormal frequencies has been explored recently. We believe that for D-dimensional de Sitter horizon we must study if the idea works. Thus taking into account the local description of the thermodynamics of horizons proposed by Padmanabhan and the results of Hod, Kunstatter, and Maggiore we study the area spectrum of the D-dimensional de Sitter horizon.

  17. Gravity mediated Dark Matter models in the de Sitter space

    OpenAIRE

    Vancea, Ion V.

    2018-01-01

    In this paper, we generalize the simplified Dark Matter models with graviton mediator to the curved space-time, in particular to the de Sitter space. We obtain the generating functional of the Green's functions in the Euclidean de Sitter space for the covariant free gravitons. We determine the generating functional of the interacting theory between Dark Matter particles and the covariant gravitons. Also, we calculate explicitly the 2-point and 3-point interacting Green's functions for the sym...

  18. 'Micromanaging de Sitter holography'

    Energy Technology Data Exchange (ETDEWEB)

    Dong, Xi; Horn, Bart; /SLAC /Stanford U., Phys. Dept. /Santa Barbara, KITP; Silverstein, Eva; /Santa Barbara, KITP /SLAC /Stanford U., Phys. Dept.; Torroba, Gonzalo; /SLAC /Stanford U., Phys. Dept. /Santa Barbara, KITP

    2010-08-26

    We develop tools to engineer de Sitter vacua with semi-holographic duals, using elliptic fibrations and orientifolds to uplift Freund-Rubin compactifications with CFT duals. The dual brane construction is compact and constitutes a microscopic realization of the dS/dS correspondence, realizing d-dimensional de Sitter space as a warped compactification down to (d-1)-dimensional de Sitter gravity coupled to a pair of large-N matter sectors. This provides a parametric microscopic interpretation of the Gibbons-Hawking entropy. We illustrate these ideas with an explicit class of examples in three dimensions, and describe ongoing work on four-dimensional constructions. The Gibbons-Hawking entropy of the de Sitter horizon [1] invites a microscopic interpretation and a holographic formulation of inflating spacetimes. Much progress was made in the analogous problem in black hole physics using special black holes in string theory whose microstates could be reliably counted, such as those analyzed in [2,3]; this led to the AdS/CFT correspondence [4]. In contrast, a microscopic understanding of the entropy of de Sitter space is more difficult for several reasons including its potential dynamical connections to other backgrounds (metastability), the absence of a non-fluctuating timelike boundary, and the absence of supersymmetry. In this paper, we develop a class of de Sitter constructions in string theory, built up from AdS/CFT dual pairs along the lines of [5], which are simple enough to provide a microscopic accounting of the parametric scaling of the Gibbons-Hawking entropy. These models realize microscopically a semi-holographic description of metastable de Sitter space which had been derived macroscopically in [6]. It would also be interesting to connect this to other approaches to de Sitter holography such as [7, 8] and to other manifestations of the de Sitter entropy such as [9]. The construction is somewhat analogous to neutral black branes analyzed in [11]. We will

  19. Hawking radiation from black holes in de Sitter spaces

    International Nuclear Information System (INIS)

    Jiang Qingquan

    2007-01-01

    Recently, Hawking radiation has been treated, by Robinson and Wilczek (2005 Phys. Rev. Lett. 95 011303), as a compensating flux of the energy-momentum tensor required to cancel a gravitational anomaly at the event horizon (EH) of a Schwarzschild-type black hole. In this paper, motivated by this work, Hawking radiation from the event horizon (EH) and the de Sitter cosmological horizon (CH) of black holes in de Sitter spaces, specifically including the purely de Sitter black hole and the static, spherically symmetric Schwarzschild-de Sitter black hole as well as the rotating Kerr-de Sitter black hole, have been studied by anomalies. The results show that the gauge-current and energy-momentum tensor fluxes, required to restore gauge invariance and general coordinate covariance at the EH and the CH, are precisely equal to those of Hawking radiation from the EH and the CH, respectively. It should be noted that gauge and gravitational anomalies taking place at the CH arise from the fact that the effective field theory is formulated inside the CH to integrate out the classically irrelevant outgoing modes at the CH, which are different from those at the black hole horizon

  20. A de Sitter tachyonic braneworld revisited

    Science.gov (United States)

    Barbosa-Cendejas, Nandinii; Cartas-Fuentevilla, Roberto; Herrera-Aguilar, Alfredo; Rigel Mora-Luna, Refugio; da Rocha, Roldão

    2018-01-01

    Within the framework of braneworlds, several interesting physical effects can be described in a wide range of energy scales, starting from high-energy physics to cosmology and low-energy physics. An usual way to generate a thick braneworld model relies in coupling a bulk scalar field to higher dimensional warped gravity. Quite recently, a novel braneworld was generated with the aid of a tachyonic bulk scalar field, having several remarkable properties. It comprises a regular and stable solution that contains a relevant 3-brane with de Sitter induced metric, arising as an exact solution to the 5D field equations, describing the inflationary eras of our Universe. Besides, it is asymptotically flat, despite of the presence of a negative 5D cosmological constant, which is an interesting feature that contrasts with most of the known, asymptotically either dS or AdS models. Moreover, it encompasses a graviton spectrum with a single massless bound state, accounting for 4D gravity localized on the brane, separated from the continuum of Kaluza-Klein massive graviton modes by a mass gap that makes the 5D corrections to Newton's law to decay exponentially. Finally, gauge, scalar and fermion fields are also shown to be localized on this braneworld. In this work, we show that this tachyonic braneworld allows for a nontrivial solution with a vanishing 5D cosmological constant that preserves all the above mentioned remarkable properties with a less amount of parameters, constituting an important contribution to the construction of a realistic cosmological braneworld model.

  1. de Sitter geodesics: reappraising the notion of motion

    Science.gov (United States)

    Pereira, J. G.; Sampson, A. C.

    2012-05-01

    The de Sitter spacetime is transitive under a combination of translations and proper conformal transformations. Its usual family of geodesics, however, does not take into account this property. As a consequence, there are points in de Sitter spacetime which cannot be joined to each other by any one of these geodesics. By taking into account the appropriate transitivity properties in the variational principle, a new family of maximizing trajectories is obtained, whose members are able to connect any two points of the de Sitter spacetime. These geodesics introduce a new notion of motion, given by a combination of translations and proper conformal transformations, which may possibly become important at very-high energies, where conformal symmetry plays a significant role.

  2. IR finite graviton propagators in de Sitter spacetime

    Energy Technology Data Exchange (ETDEWEB)

    Faizal, Mir [University of Lethbridge, Department of Physics and Astronomy, Lethbridge, AB (Canada); Upadhyay, Sudhaker; Mandal, Bhabani Prasad [Banaras Hindu University, Department of Physics, Varanasi (India)

    2016-04-15

    The graviton propagator diverges in certain gauges in de Sitter spacetime. We address this problem in this work by generalizing the infinitesimal BRST transformations in de Sitter spacetime to finite field-dependent BRST (FFBRST) transformations. These FFBRST transformations are a symmetry of the classical action, but they do not leave the path integral measure invariant for the graviton theory in de Sitter spacetime. Due to the non-trivial Jacobian of such a finite transformation the path integral measure changes and hence the FFBRST transformation is capable of relating theories in two different gauges. We explicitly construct the FFBRST transformation which relates the theory with a diverging graviton two-point function to a theory with an infrared finite graviton. The FFBRST transformation thus establishes that the divergence in a graviton two-point function may be only a gauge artifact. (orig.)

  3. Quantum physics of an elementary system in de Sitter space

    International Nuclear Information System (INIS)

    Rabeie, A.

    2012-01-01

    We present the coherent states of a scalar massive particle on 1+3-de Sitter space. These states are vectors in Hilbert space, and they are labeled by points in the associated phase space. To do this, we use the fact that the phase space of a scalar massive particle on 1+3-de Sitter space is a cotangent bundle T * (S 3 ) which is isomorphic with the complex sphere S C 3 . Then by using the heat kernel on '' S C 3 '' that was presented by Hall-Mitchell, we construct our coherent states. At the end, by these states we quantize the classical kinetic energy on de Sitter space. (orig.)

  4. Rest frames and relativistic effects on de Sitter spacetimes

    Energy Technology Data Exchange (ETDEWEB)

    Cotaescu, Ion I. [West University of Timisoara, Timisoara (Romania)

    2017-07-15

    It is shown that the Nachtmann boosting method of introducing coordinates on de Sitter manifolds can be completed with suitable gauge transformations able to keep under control the transformation under isometries of the conserved quantities. With this method, the rest local charts (or natural frames) are defined pointing out the role of the conserved quantities in investigating the relative geodesic motion. The advantages of this approach can be seen from the applications presented here. For the first time, the simple kinematic effects, the electromagnetic field of a free falling charge and the binary fission are solved in terms of conserved quantities on the expanding portion of the de Sitter spacetime. (orig.)

  5. Holographic central charge for 2-dimensional de Sitter space

    International Nuclear Information System (INIS)

    Medved, A.J.M.

    2003-01-01

    Recently, investigations have begun into a holographic duality for two-dimensional de Sitter space. In this paper we evaluate the associated central charge, using a modified version of the canonical Hamiltonian method that was first advocated by Catelani and co-workers. Our computation agrees with that of a prior work (Cadoni et al.), but we argue that the method used here is, perhaps, aesthetically preferable on holographic grounds. We also confirm an agreement between the Cardy and thermodynamic entropy, thus providing further support for the conjectured two-dimensional de Sitter-conformal field theory correspondence

  6. Entropy of Kerr-de Sitter black hole

    Science.gov (United States)

    Li, Huai-Fan; Ma, Meng-Sen; Zhang, Li-Chun; Zhao, Ren

    2017-07-01

    Based on the consideration that the black hole horizon and the cosmological horizon of Kerr-de Sitter black hole are not independent of each other, we conjecture the total entropy of the system should have an extra term contributed from the correlations between the two horizons, except for the sum of the two horizon entropies. By employing globally effective first law and effective thermodynamic quantities, we obtain the corrected total entropy and find that the region of stable state for Kerr-de Sitter is related to the angular velocity parameter a, i.e., the region of stable state becomes bigger as the rotating parameters a is increases.

  7. Consistency of scalar potentials from quantum de Sitter space

    Science.gov (United States)

    Espinosa, José R.; Fortin, Jean-François; Trépanier, Maxime

    2016-06-01

    Consistency of the unconventional view of de Sitter space as a quantum theory of gravity with a finite number of degrees of freedom requires that Coleman-De Luccia tunneling rates to vacua with negative cosmological constant should be interpreted as recurrences to low-entropy states. This demand translates into two constraints, or consistency conditions, on the scalar potential that are generically as follows: (1) the distance in field space between the de Sitter vacuum and any other vacuum with negative cosmological constant must be of the order of the reduced Planck mass or larger and (2) the fourth root of the vacuum energy density of the de Sitter vacuum must be smaller than the fourth root of the typical scale of the scalar potential. These consistency conditions shed a different light on both outstanding hierarchy problems of the standard model of particle physics: the scale of electroweak symmetry breaking and the scale of the cosmological constant. Beyond the unconventional interpretation of quantum de Sitter space, we complete the analytic understanding of the thin-wall approximation of Coleman-De Luccia tunneling, extend its numerical analysis to generic potentials and discuss the role of gravity in stabilizing the standard model potential.

  8. Zero modes in de Sitter background

    Energy Technology Data Exchange (ETDEWEB)

    Einhorn, Martin B. [Kavli Institute for Theoretical Physics, University of California,Santa Barbara, CA 93106-4030 (United States); Jones, D.R. Timothy [Kavli Institute for Theoretical Physics, University of California,Santa Barbara, CA 93106-4030 (United States); Dept. of Mathematical Sciences, University of Liverpool,Liverpool L69 3BX (United Kingdom)

    2017-03-28

    There are five well-known zero modes among the fluctuations of the metric of de Sitter (dS) spacetime. For Euclidean signature, they can be associated with certain spherical harmonics on the S{sup 4} sphere, viz., the vector representation 5 of the global SO(5) isometry. They appear, for example, in the perturbative calculation of the on-shell effective action of dS space, as well as in models containing matter fields. These modes are shown to be associated with collective modes of S{sup 4} corresponding to certain coherent fluctuations. When dS space is embedded in flat five dimensions E{sup 5}, they may be seen as a legacy of translation of the center of the S{sup 4} sphere. Rigid translations of the S{sup 4}-sphere on E{sup 5} leave the classical action invariant but are unobservable displacements from the point of view of gravitational dynamics on S{sup 4}. Thus, unlike similar moduli, the center of the sphere is not promoted to a dynamical degree of freedom. As a result, these zero modes do not signify the possibility of physically realizable fluctuations or flat directions for the metric of dS space. They are not associated with Killing vectors on S{sup 4} but can be identified with certain non-isometric, conformal Killing forms that locally correspond to a rescaling of the volume element dV{sub 4}. We frame much of our discussion in the context of renormalizable gravity, but, to the extent that they only depend upon the global symmetry of the background, the conclusions should apply equally to the corresponding zero modes found in Einstein gravity. Although their existence has only been demonstrated at one-loop, we expect that these zero modes will be present to all orders in perturbation theory. They will occur for Lorentzian signature as well, so long as the hyperboloid H{sup 4} is locally stable, but there remain certain infrared issues that need to be clarified. We conjecture that they will appear in any gravitational theory having dS background as a

  9. Tracking our universe to de Sitter by a Horndeski scalar

    Science.gov (United States)

    Germani, Cristiano; Martín-Moruno, Prado

    2017-12-01

    Assuming both that our Universe is evolving into a de Sitter space and a vanishing cosmological constant, leaves only the option that the observed acceleration is provided by a "kinetic" energy of a scalar field. From an effective field theory point of view, the absence of Ostrogradsky instabilities restricts the choice to shift-symmetric Horndeski theories. Within these theories, we find the conditions for the existence of a de Sitter critical point in a universe filled by matter, radiation and a Horndeski scalar. Moreover, we show that this point is a universal attractor and we provide the tracking trajectory. Therefore, if a de Sitter fixed point exists within these models, our Universe will eventually evolve into a de Sitter space. As an example, we have discussed the case of the combined Galileon-Slotheon system, in which the Galileon is kinetically non-minimal coupled to the Einstein tensor. Interestingly, we have also found that the tracker trajectory of this system does not follow previous literature assumptions.

  10. Snyder-de Sitter model from two-time physics

    International Nuclear Information System (INIS)

    Carrisi, M. C.; Mignemi, S.

    2010-01-01

    We show that the symplectic structure of the Snyder model on a de Sitter background can be derived from two-time physics in seven dimensions and propose a Hamiltonian for a free particle consistent with the symmetries of the model.

  11. Equatorial circular orbits in the Kerr-de Sitter spacetimes

    International Nuclear Information System (INIS)

    Stuchlik, Zdenek; Slany, Petr

    2004-01-01

    Equatorial motion of test particles in Kerr-de Sitter spacetimes is considered. Circular orbits are determined, their properties are discussed for both black-hole and naked-singularity spacetimes, and their relevance for thin accretion disks is established. The circular orbits constitute two families that coalesce at the so-called static radius. The orientation of the motion along the circular orbits is, in accordance with case of asymptotically flat Kerr spacetimes, defined by relating the motion to the locally nonrotating frames. The minus-family orbits are all counterrotating, while the plus-family orbits are usually corotating relative to these frames. However, the plus-family orbits become counterrotating in the vicinity of the static radius in all Kerr-de Sitter spacetimes, and they become counterrotating in the vicinity of the ring singularity in Kerr-de Sitter naked-singularity spacetimes with a low enough rotational parameter. In such spacetimes, the efficiency of the conversion of the rest energy into heat energy in the geometrically thin plus-family accretion disks can reach extremely high values exceeding the efficiency of the annihilation process. The transformation of a Kerr-de Sitter naked singularity into an extreme black hole due to accretion in the thin disks is briefly discussed for both the plus-family and minus-family disks. It is shown that such a conversion leads to an abrupt instability of the innermost parts of the plus-family accretion disks that can have strong observational consequences

  12. De Sitter universes and the emerging landscape in string theory

    Indian Academy of Sciences (India)

    We discuss a recent proposal to construct de Sitter vacua in string theory. It is based on flux compactifications in string theory where all the moduli are stabilised and supersymmetry is broken with control. The resulting picture is that of a complicated landscape with many vacua of widely varying values for the cosmological ...

  13. de Sitter limit of inflation and nonlinear perturbation theory

    DEFF Research Database (Denmark)

    R. Jarnhus, Philip; Sloth, Martin Snoager

    2007-01-01

    We study the fourth order action of the comoving curvature perturbation in an inflationary universe in order to understand more systematically the de Sitter limit in nonlinear cosmological perturbation theory. We derive the action of the curvature perturbation to fourth order in the comoving gaug...

  14. Gauge gravity in noncommutative de Sitter space and pair creation

    Energy Technology Data Exchange (ETDEWEB)

    Mebarki, N; Khodja, L; Aisaoui, H [Laboratoire de Physique Mathematique et Subatomique, Faculte des Sciences, Mentouri University, Constantine (Algeria); Zaim, S [Departement de Physique, Faculte des Sciences, Universite Hadj Lakhdar, Batna (Algeria)], E-mail: zaimslimane@yahoo.fr

    2008-10-15

    From the invariance of the generalized space-time non-commutative commutation relations, local Poincare and general coordinate transformations are derived. Moreover, a generalized Dirac equation is obtained. Applied to the de Sitter universe, it is shown that the space-time non-commutativity contributes to the particle creation process and induces a Casimir-like effect.

  15. On the solution of the Dirac equation in de Sitter space

    International Nuclear Information System (INIS)

    Klishevich, V V; Tyumentsev, V A

    2005-01-01

    It is shown that the maximal number of first-order symmetry operators for the Dirac equation (including spin symmetries), both in arbitrary signature flat space and in de Sitter space, is equal. The isomorphic representation of 11-dimensional nonlinear symmetry algebra (W-algebra) of first-order operators for the Dirac operator in flat space and de Sitter space is considered. The algebra is an extension of the Lie algebra of the group of pseudo-orthogonal rotations and this extension is unique. We have found all linear Lie subalgebras in the nonlinear algebra that satisfy the conditions of the noncommutative integration theorem. Using one subalgebra we have integrated the Dirac equation in the generalized spherical system of coordinates and have constructed the complete class of exact solutions. The solution is found by a method that differs from the variable separation method and is new in the literature. The massive particle spectrum, models of particle into antiparticle transmutation, the disappearance of particles and the quantization conditions of the motion are discussed. One can use the results of the paper to pose the boundary problem for the Dirac equation in de Sitter space if the interval is used in the boundary condition. As an example, we consider a model of asymptotically flat space that is glued from the de Sitter space and flat space. We interpret the model as a gravitational well or barrier

  16. On classical de Sitter and Minkowski solutions with intersecting branes

    Science.gov (United States)

    Andriot, David

    2018-03-01

    Motivated by the connection of string theory to cosmology or particle physics, we study solutions of type II supergravities having a four-dimensional de Sitter or Minkowski space-time, with intersecting D p -branes and orientifold O p -planes. Only few such solutions are known, and we aim at a better characterisation. Modulo a few restrictions, we prove that there exists no classical de Sitter solution for any combination of D 3/ O 3 and D 7/ O 7, while we derive interesting constraints for intersecting D 5/ O 5 or D 6/ O 6, or combinations of D 4/ O 4 and D 8/ O 8. Concerning classical Minkowski solutions, we understand some typical features, and propose a solution ansatz. Overall, a central information appears to be the way intersecting D p / O p overlap each other, a point we focus on.

  17. Instanton transition in thermal and moduli deformed de Sitter cosmology

    International Nuclear Information System (INIS)

    Kounnas, Costas; Partouche, Herve

    2008-01-01

    We consider the de Sitter cosmology deformed by the presence of a thermal bath of radiation and/or time-dependent moduli fields. Depending on the parameters, either a first or second-order phase transition can occur. In the first case, an instanton allows a double analytic continuation. It induces a probability to enter the inflationary evolution by tunnel effect from another cosmological solution. The latter starts with a big bang and, in the case the transition does not occur, ends with a big crunch. A temperature duality exchanges the two cosmological branches. In the limit where the pure de Sitter universe is recovered, the tunnel effect reduces to a 'creation from nothing', due to the vanishing of the big bang branch. However, the latter may be viable in some range of the deformation parameter. In the second case, there is a smooth evolution from a big bang to the inflationary phase

  18. Massless Interacting Scalar Fields in de Sitter space

    CERN Document Server

    López Nacir, Diana

    2016-10-28

    We present a method to compute the two-point functions for an $O(N)$ scalar field model in de Sitter spacetime, avoiding the well known infrared problems for massless fields. The method is based on an exact treatment of the Euclidean zero modes and a perturbative one of the nonzero modes, and involves a partial resummation of the leading secular terms. This resummation, crucial to obtain a decay of the correlation functions, is implemented along with a double expansion in an effective coupling constant $\\sqrt\\lambda$ and in $1/N$. The results reduce to those known in the leading infrared approximation and coincide with the ones obtained directly in Lorentzian de Sitter spacetime in the large $N$ limit. The new method allows for a systematic calculation of higher order corrections both in $\\sqrt\\lambda$ and in $1/N$.

  19. Semiclassical fermion pair creation in de Sitter spacetime

    Energy Technology Data Exchange (ETDEWEB)

    Stahl, Clément, E-mail: clement.stahl@icranet.org; Eckhard, Strobel, E-mail: eckhard.strobel@irap-phd.eu [ICRANet, Piazzale della Repubblica 10, 65122 Pescara (Italy); Dipartimento di Fisica, Università di Roma “La Sapienza”, Piazzale Aldo Moro 5, 00185 Rome (Italy); Université de Nice Sophia Antipolis, 28 Avenue de Valrose, 06103 Nice Cedex 2 (France)

    2015-12-17

    We present a method to semiclassically compute the pair creation rate of bosons and fermions in de Sitter spacetime. The results in the bosonic case agree with the ones in the literature. We find that for the constant electric field the fermionic and bosonic pair creation rate are the same. This analogy of bosons and fermions in the semiclassical limit is known from several flat spacetime examples.

  20. Quantum corrections for spinning particles in de Sitter

    Science.gov (United States)

    Fröb, Markus B.; Verdaguer, Enric

    2017-04-01

    We compute the one-loop quantum corrections to the gravitational potentials of a spinning point particle in a de Sitter background, due to the vacuum polarisation induced by conformal fields in an effective field theory approach. We consider arbitrary conformal field theories, assuming only that the theory contains a large number N of fields in order to separate their contribution from the one induced by virtual gravitons. The corrections are described in a gauge-invariant way, classifying the induced metric perturbations around the de Sitter background according to their behaviour under transformations on equal-time hypersurfaces. There are six gauge-invariant modes: two scalar Bardeen potentials, one transverse vector and one transverse traceless tensor, of which one scalar and the vector couple to the spinning particle. The quantum corrections consist of three different parts: a generalisation of the flat-space correction, which is only significant at distances of the order of the Planck length; a constant correction depending on the undetermined parameters of the renormalised effective action; and a term which grows logarithmically with the distance from the particle. This last term is the most interesting, and when resummed gives a modified power law, enhancing the gravitational force at large distances. As a check on the accuracy of our calculation, we recover the linearised Kerr-de Sitter metric in the classical limit and the flat-space quantum correction in the limit of vanishing Hubble constant.

  1. Cybernetically sound organizational structures II: Relating de Sitter's design theory to Beer's viable system model

    NARCIS (Netherlands)

    Achterbergh, J.M.I.M.; Vriens, D.J.

    2011-01-01

    - Purpose – The purpose of this paper is to show how the viable system model (VSM) and de Sitter's design theory can complement each other in the context of the diagnosis and design of viable organizations. - Design/methodology/approach – Key concepts from Beer's model and de Sitter's design theory

  2. Sequestered de Sitter string scenarios: soft-terms

    Science.gov (United States)

    Aparicio, Luis; Cicoli, Michele; Krippendorf, Sven; Maharana, Anshuman; Muia, Francesco; Quevedo, Fernando

    2014-11-01

    We analyse soft supersymmetry breaking in type IIB de Sitter string vacua after moduli stabilisation, focussing on models in which the Standard Model is sequestered from the supersymmetry breaking sources and the spectrum of soft-terms is hierarchically smaller than the gravitino mass m 3/2. Due to this feature, these models are compatible with gauge coupling unification and TeV scale supersymmetry with no cosmological moduli problem. We determine the influence on soft-terms of concrete realisations of de Sitter vacua constructed from supersymmetric effective actions. One of these scenarios provides the first study of soft-terms for consistent string models embedded in a compact Calabi-Yau manifold with all moduli stabilised. Depending on the moduli dependence of the Kähler metric for matter fields and on the mechanism responsible to obtain a de Sitter vacuum, we find two scenarios for phenomenology: (i) a split-supersymmetry scenario where gaugino masses are suppressed with respect to scalar masses: M 1/2 ˜ m 3/2 ɛ ≪ m 0 ˜ m 3/2 ≪ m 3/2 for ɛ ˜ m 3/2 /M P ≪ 1; (ii) a typical MSSM scenario where all soft-terms are of the same order: M 1/2 ˜ m 0 ˜ m 3/2 ɛ ≪ m 3/2. Background fluxes determine the numerical coefficients of the soft-terms allowing for small variations of parameters as is necessary to confront data and to interpolate between different scenarios. We comment on different stringy origins of the μ-term and potential sources of desequestering.

  3. Quantum scalar corrections to the gravitational potentials on de Sitter background

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sohyun [Korea Astronomy and Space Science Institute,Daejeon, 305-348 (Korea, Republic of); Prokopec, Tomislav [Institute of Theoretical Physics, Spinoza Instituteand the Center for Extreme Matter and Emergent Phenomena (EMME),Utrecht University, Leuvenlaan 4, 3584 CE Utrecht (Netherlands); Woodard, R.P. [Department of Physics, University of Florida,Gainesville, FL 32611 (United States)

    2016-01-13

    We employ the graviton self-energy induced by a massless, minimally coupled (MMC) scalar on de Sitter background to compute the quantum corrections to the gravitational potentials of a static point particle with a mass M. The Schwinger-Keldysh formalism is used to derive real and causal effective field equations. When evaluated at the one-loop order, the gravitational potentials exhibit a secular decrease in the observed gravitational coupling G. This can also be interpreted as a (time dependent) anti-screening of the mass M.

  4. Holographic Entropy on the Brane in de Sitter Schwarzschild Space

    OpenAIRE

    Ogushi, Sachiko

    2001-01-01

    The relationship between the entropy of de Sitter (dS) Schwarzschild space and that of the CFT, which lives on the brane, is discussed by using Friedmann-Robertson-Walker (FRW) equations and Cardy-Verlinde formula. The cosmological constant appears on the brane with time-like metric in dS Schwarzschild background. On the other hand, in case of the brane with space-like metric in dS Schwarzschild background, the cosmological constant of the brane does not appear because we can choose brane ten...

  5. Schwinger mechanism in electromagnetic field in de Sitter spacetime

    Directory of Open Access Journals (Sweden)

    Bavarsad Ehsan

    2018-01-01

    Full Text Available We investigate Schwinger scalar pair production in a constant electromagnetic field in de Sitter (dS spacetime. We obtain the pair production rate, which agrees with the Hawking radiation in the limit of zero electric field in dS. The result describes how a cosmic magnetic field affects the pair production rate. In addition, using a numerical method we study the effect of the magnetic field on the induced current. We find that in the strong electromagnetic field the current has a linear response to the electric and magnetic fields, while in the infrared regime, is inversely proportional to the electric field and leads to infrared hyperconductivity.

  6. Schwinger mechanism in electromagnetic field in de Sitter spacetime

    Science.gov (United States)

    Bavarsad, Ehsan; Pyo Kim, Sang; Stahl, Clément; Xue, She-Sheng

    2018-01-01

    We investigate Schwinger scalar pair production in a constant electromagnetic field in de Sitter (dS) spacetime. We obtain the pair production rate, which agrees with the Hawking radiation in the limit of zero electric field in dS. The result describes how a cosmic magnetic field affects the pair production rate. In addition, using a numerical method we study the effect of the magnetic field on the induced current. We find that in the strong electromagnetic field the current has a linear response to the electric and magnetic fields, while in the infrared regime, is inversely proportional to the electric field and leads to infrared hyperconductivity.

  7. Inflation in de Sitter spacetime and CMB large scale anomaly

    Science.gov (United States)

    Zhao, Dong; Li, Ming-Hua; Wang, Ping; Chang, Zhe

    2015-09-01

    The influence of cosmological constant-type dark energy in the early universe is investigated. This is accommodated by a new dispersion relation in de Sitter spacetime. We perform a global fit to explore the cosmological parameter space by using the CosmoMC package with the recently released Planck TT and WMAP polarization datasets. Using the results from the global fit, we compute a new CMB temperature-temperature (TT) spectrum. The obtained TT spectrum has lower power compared with that based on the ACDM model at large scales. Supported by National Natural Science Foundation of China (11375203)

  8. Attracted to de Sitter: cosmology of the linear Horndeski models

    Energy Technology Data Exchange (ETDEWEB)

    Martín-Moruno, Prado; Nunes, Nelson J.; Lobo, Francisco S.N., E-mail: pmmoruno@fc.ul.pt, E-mail: njnunes@fc.ul.pt, E-mail: fslobo@fc.ul.pt [Instituto de Astrofísica e Ciências do Espaço, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, PT1749-016 Lisboa (Portugal)

    2015-05-01

    We consider Horndeski cosmological models, with a minisuperspace Lagrangian linear in the field derivative, that are able to screen any vacuum energy and material content leading to a spatially flat de Sitter vacuum fixed by the theory itself. Furthermore, we investigate particular models with a cosmic evolution independent of the material content and use them to understand the general characteristics of this framework. We also consider more realistic models, which we denote the ''term-by-term'' and ''tripod'' models, focusing attention on cases in which the critical point is indeed an attractor solution and the cosmological history is of particular interest.

  9. The deflationary universe: An instability of the de Sitter universe

    International Nuclear Information System (INIS)

    Barrow, J.D.

    1986-01-01

    The relevance is discussed of the initial value structure of the cosmological problem for inflationary explanations of its present structure. Existing proofs of the cosmic ''no hair'' conjecture are found to make use of an unrealistic strong energy condition on the stress tensor of the matter fields not driving the inflation. It is shown by explicit example that the no hair conjecture fails even in isotropic cosmological models if the strong energy condition is relaxed. A class of exact cosmological models are given which begin in a de Sitter state but subsequently deflate towards the flat Friedman model. Various implications of these examples are discussed. (orig.)

  10. On de Sitter-like and Minkowski-like spacetimes

    International Nuclear Information System (INIS)

    Luebbe, Christian; Kroon, Juan Antonio Valiente

    2009-01-01

    Friedrich's proofs for the global existence results of de Sitter-like spacetimes and of semi-global existence of Minkowski-like spacetimes (Friedrich 1986 Commun. Math. Phys. 107 587) are re-examined and discussed, making use of the extended conformal field equations and a gauge based on conformal geodesics. In this gauge, the location of the conformal boundary of the spacetimes is known a priori once the initial data have been prescribed. Thus, it provides an analysis which is conceptually and calculationally simpler.

  11. Gravitational radiation reaction in the NUT-de Sitter spacetime

    International Nuclear Information System (INIS)

    Ahmed, M.

    1988-07-01

    The equations for gravitational perturbation in the NUT-de Sitter spacetime are obtained. Using these equations, some preliminary calculations have been made with a view to constructing the retarded Green functions. Then with the help of the retarded Green functions, the radiative Green functions have been constructed. With the aid of these radiative Green functions, the reaction force on a particle is computed and this reaction force is then shown to account correctly for the energy and the angular momentum carried away by gravitational radiation to infinity and to the horizon. (author). 9 refs

  12. ADM Mass for Asymptotically de Sitter Space-Time

    International Nuclear Information System (INIS)

    Huang Shiming; Yue Ruihong; Jia Dongyan

    2010-01-01

    In this paper, an ADM mass formula for asymptotically de Sitter(dS) space-time is derived from the energy-momentum tensor. We take the vacuum dS space as the background and investigate the ADM mass of the (d + 3)-dimensional sphere-symmetric space with a positive cosmological constant, and find that the ADM mass of asymptotically dS space is based on the ADM mass of Schwarzschild field and the cosmological background brings some small mass contribution as well. (general)

  13. de Sitter Space in Non-Critical String Theory

    Energy Technology Data Exchange (ETDEWEB)

    Silverstein, Eva M

    2002-08-13

    Supercritical string theories in D > 10 dimensions with no moduli are described, generalizing the asymmetric orientifold construction of one of the authors [1]. By taking the number of dimensions to be large and turning on fluxes, dilaton potentials are generated with nontrivial minima at arbitrarily small cosmological constant and D-dimensional string coupling, separated by a barrier from a flat-space linear dilaton region, but possibly suffering from strong coupling problems. The general issue of the decay of a de Sitter vacuum to flat space is discussed. For relatively small barriers, such decays are described by gravitational instantons. It is shown that for a sufficiently large potential barrier, the bubble wall crosses the horizon. At the same time the instanton decay time exceeds the Poincare recurrence time. It is argued that the inclusion of such instantons is neither physically meaningful nor consistent with basic principles such as causality. This raises the possibility that such de Sitter vacua are effectively stable. In the case of the supercritical flux models, decays to the linear dilaton region can be forbidden by such large barriers, but decays to lower flux vacua including AdS minima nevertheless proceed consistently with this criterion. These models provide concrete examples in which cosmological constant reduction by flux relaxation can be explored.

  14. Quasinormal modes of Kerr-de Sitter black holes

    International Nuclear Information System (INIS)

    Yoshida, Shijun; Uchikata, Nami; Futamase, Toshifumi

    2010-01-01

    We calculate the fundamental quasinormal modes of the Kerr-de Sitter black hole for the first time. In order to calculate the quasinormal modes, we employ the master equations derived by Suzuki, Takasugi, and Umetsu, who transform the Teukolsky equations for the Kerr-de Sitter black hole into the standard form of the Heun's equation. The transformed functions are expanded around the outer horizon of the black hole or the symmetric axis in the Froebenius series whose coefficients satisfy a three-term recurrence relation. These three-term recurrence relations allow us to use Leaver's continued fraction method to calculate the angular separation constant and the quasinormal mode frequency. Any unstable fundamental quasinormal mode is not found in this paper. It is also observed that for some black holes characterized by a large mass parameter, some retrograde modes in the slow rotation limit become prograde as the black hole spin increases. This phenomenon does not occur for the fundamental modes of the Kerr black hole.

  15. De Sitter en Einstein. ‘Het lijkt mij dat Einstein hier een vergissing begaan heeft’

    Directory of Open Access Journals (Sweden)

    Jan Guichelaar

    2016-10-01

    Full Text Available De Sitter and EinsteinWillem de Sitter’s interest in gravity was based on his work on celestial mechanics, in particular on the four big moons of Jupiter. His work on cosmology was based on the general theory of relativity of Albert Einstein. De Sitter published in 1917, on request of Arthur Eddington to inform the English astronomers, a series of four articles in The Observatory and the Monthly Notices of the Royal Astronomical Society. Einstein developed his own cosmological models, containing mass. De Sitter found a different solution and described a universe without mass. Einstein could not accept De Sitter’s model and they ‘fought out’ two controversies in their correspondence. In theend Einstein had to confess De Sitter was mainly right in his criticisms. In 1932 Einstein and De Sitter published an article on a new model, the so-called Einstein-De Sitter Model of the universe. So, De Sitter was able to do fundamental work in classical celestial mechanics as well as in the new cosmological theories.

  16. Anti-de Sitter gravitational collapse

    CERN Document Server

    Husain, V; Preston, B; Birukou, M

    2003-01-01

    We describe a formalism for studying spherically symmetric collapse of the massless scalar field in any spacetime dimension, and for any value of the cosmological constant LAMBDA. The formalism is used for numerical simulations of gravitational collapse in four spacetime dimensions with negative LAMBDA. We observe critical behaviour at the onset of black-hole formation, and find that the critical exponent is independent of LAMBDA. (letter to the editor)

  17. Higher Spins without (Anti-de Sitter

    Directory of Open Access Journals (Sweden)

    Stefan Prohazka

    2018-01-01

    Full Text Available Can the holographic principle be extended beyond the well-known AdS/CFT correspondence? During the last couple of years, there has been a substantial amount of research trying to find answers for this question. In this work, we provide a review of recent developments of three-dimensional theories of gravity with higher spin symmetries. We focus in particular on a proposed holographic duality involving asymptotically flat spacetimes and higher spin extended bms 3 symmetries. In addition, we also discuss developments concerning relativistic and nonrelativistic higher spin algebras. As a special case, Carroll gravity will be discussed in detail.

  18. Holographic Entropy on the Brane in de Sitter Schwarzschild Space

    Science.gov (United States)

    Ogushi, Sachiko

    The relationship between the entropy of de Sitter (dS) Schwarzschild space and that of the CFT, which lives on the brane, is discussed by using Friedmann-Robertson-Walker (FRW) equations and Cardy-Verlinde formula. The cosmological constant appears on the brane with time-like metric in dS Schwarzschild background. On the other hand, in case of the brane with space-like metric in dS Schwarzschild background, the cosmological constant of the brane does not appear because we can choose brane tension to cancel it. We show that when the brane crosses the horizon of dS Schwarzschild black hole, both for time-like and space-like cases, the entropy of the CFT exactly agrees with the black hole entropy of five-dimensional dS background as it happens in the AdS/CFT correspondence.

  19. Quantum loop corrections of a charged de Sitter black hole

    Science.gov (United States)

    Naji, J.

    2018-03-01

    A charged black hole in de Sitter (dS) space is considered and logarithmic corrected entropy used to study its thermodynamics. Logarithmic corrections of entropy come from thermal fluctuations, which play a role of quantum loop correction. In that case we are able to study the effect of quantum loop on black hole thermodynamics and statistics. As a black hole is a gravitational object, it helps to obtain some information about the quantum gravity. The first and second laws of thermodynamics are investigated for the logarithmic corrected case and we find that it is only valid for the charged dS black hole. We show that the black hole phase transition disappears in the presence of logarithmic correction.

  20. De Sitter space in gauge/gravity duality

    Directory of Open Access Journals (Sweden)

    Lilia Anguelova

    2015-10-01

    Full Text Available We investigate gauge/gravity duality for gauge theories in de Sitter space. More precisely, we study a five-dimensional consistent truncation of type IIB supergravity, which encompasses a wide variety of gravity duals of strongly coupled gauge theories, including the Maldacena–Nunez solution and its walking deformations. We find several solutions of the 5d theory with dS4 spacetime and nontrivial profiles for (some of the scalars along the fifth (radial direction. In the process, we prove that one of the equations of motion becomes dependent on the others, for nontrivial warp factor. This dependence reduces the number of field equations and, thus, turns out to be crucial for the existence of solutions with (AdS4 spacetime. Finally, we comment on the implications of our dS4 solutions for building gravity duals of Glueball Inflation.

  1. Energy, momentum and angular momentum conservations in de Sitter gravity

    International Nuclear Information System (INIS)

    Lu, Jia-An

    2016-01-01

    In de Sitter (dS) gravity, where gravity is a gauge field introduced to realize the local dS invariance of the matter field, two kinds of conservation laws are derived. The first kind is a differential equation for a dS-covariant current, which unites the canonical energy-momentum (EM) and angular momentum (AM) tensors. The second kind presents a dS-invariant current which is conserved in the sense that its torsion-free divergence vanishes. The dS-invariant current unites the total (matter plus gravity) EM and AM currents. It is well known that the AM current contains an inherent part, called the spin current. Here it is shown that the EM tensor also contains an inherent part, which might be observed by its contribution to the deviation of the dust particle’s world line from a geodesic. All the results are compared to the ordinary Lorentz gravity. (paper)

  2. Higher order corrections to asymptotic-de Sitter inflation

    Science.gov (United States)

    Mohsenzadeh, M.; Yusofi, E.

    2017-08-01

    Since trans-Planckian considerations can be associated with the re-definition of the initial vacuum, we investigate further the influence of trans-Planckian physics on the spectra produced by the initial quasi-de Sitter (dS) state during inflation. We use the asymptotic-dS mode to study the trans-Planckian correction of the power spectrum to the quasi-dS inflation. The obtained spectra consist of higher order corrections associated with the type of geometry and harmonic terms sensitive to the fluctuations of space-time (or gravitational waves) during inflation. As an important result, the amplitude of the power spectrum is dependent on the choice of c, i.e. the type of space-time in the period of inflation. Also, the results are always valid for any asymptotic dS space-time and particularly coincide with the conventional results for dS and flat space-time.

  3. Geometrothermodynamics for black holes and de Sitter space

    Science.gov (United States)

    Kurihara, Yoshimasa

    2018-02-01

    A general method to extract thermodynamic quantities from solutions of the Einstein equation is developed. In 1994, Wald established that the entropy of a black hole could be identified as a Noether charge associated with a Killing vector of a global space-time (pseudo-Riemann) manifold. We reconstruct Wald's method using geometrical language, e.g., via differential forms defined on the local space-time (Minkowski) manifold. Concurrently, the abstract thermodynamics are also reconstructed using geometrical terminology, which is parallel to general relativity. The correspondence between the thermodynamics and general relativity can be seen clearly by comparing the two expressions. This comparison requires a modification of Wald's method. The new method is applied to Schwarzschild, Kerr, and Kerr-Newman black holes and de Sitter space. The results are consistent with previous results obtained using various independent methods. This strongly supports the validity of the area theorem for black holes.

  4. De Sitter inflationary expansion from a noncompact KK theory: a nonperturbative quantum (scalar) field formalism

    International Nuclear Information System (INIS)

    Bellini, Mauricio

    2005-01-01

    We develop a nonperturbative quantum scalar field formalism from a noncompact Kaluza-Klein (KK) theory using the induced-matter theory of gravity during inflation. We study the particular case of a de Sitter expansion for the universe

  5. Power radiated by a binary system in a de Sitter universe

    Science.gov (United States)

    Bonga, Béatrice; Hazboun, Jeffrey S.

    2017-09-01

    Gravitational waves emitted by high redshift sources propagate through various epochs of the Universe including the current era of measurable, accelerated expansion. Historically, the calculation of gravitational wave power on cosmological backgrounds is based on various simplifications, including a 1 /r -expansion and the use of an algebraic projection to retrieve the radiative degrees of freedom. On a de Sitter spacetime, recent work has demonstrated that many of these calculational techniques and approximations do not apply. Here we calculate the power emitted by a binary system on a de Sitter background using techniques tailored to de Sitter spacetime. The common expression for the power radiated by this source in an Friedmann-Lemaître-Robertson-Walker spacetime, calculated using far wave-zone techniques, gives the same expression as the late time expansion specialized to the de Sitter background in the high-frequency approximation.

  6. Dynamics of quantum entanglement in de Sitter spacetime and thermal Minkowski spacetime

    Directory of Open Access Journals (Sweden)

    Zhiming Huang

    2017-10-01

    Full Text Available We investigate the dynamics of entanglement between two atoms in de Sitter spacetime and in thermal Minkowski spacetime. We treat the two-atom system as an open quantum system which is coupled to a conformally coupled massless scalar field in the de Sitter invariant vacuum or to a thermal bath in the Minkowski spacetime, and derive the master equation that governs its evolution. We compare the phenomena of entanglement creation, degradation, revival and enhancement for the de Sitter spacetime case with that for the thermal Minkowski spacetime case. We find that the entanglement dynamics of two atoms for these two spacetime cases behave quite differently. In particular, the two atoms interacting with the field in the thermal Minkowski spacetime (with the field in the de Sitter-invariant vacuum, under certain conditions, could be entangled, while they would not become entangled in the corresponding de Sitter case (in the corresponding thermal Minkowski case. Thus, although a single static atom in the de Sitter-invariant vacuum responds as if it were bathed in thermal radiation in a Minkowski universe, with the help of the different dynamic evolution behaviors of entanglement for two atoms one can in principle distinguish these two universes.

  7. Instanton tunneling for de Sitter space with real projective spatial sections

    Energy Technology Data Exchange (ETDEWEB)

    Ong, Yen Chin [Center for Astronomy and Astrophysics, Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240 (China); Yeom, Dong-han, E-mail: ongyenchin@sjtu.edu.cn, E-mail: innocent.yeom@gmail.com [Leung Center for Cosmology and Particle Astrophysics, National Taiwan University, Taipei 10617, Taiwan (China)

    2017-04-01

    The physics of tunneling from one spacetime to another is often understood in terms of instantons. For some instantons, it was recently shown in the literature that there are two complementary ''interpretations'' for their analytic continuations. Dubbed ''something-to-something'' and ''nothing-to-something'' interpretations, respectively, the former involves situation in which the initial and final hypersurfaces are connected by a Euclidean manifold, whereas the initial and final hypersurfaces in the latter case are not connected in such a way. We consider a de Sitter space with real projective space RP{sup 3} spatial sections, as was originally understood by de Sitter himself. This original version of de Sitter space has several advantages over the usual de Sitter space with S{sup 3} spatial sections. In particular, the interpretation of the de Sitter entropy as entanglement entropy is much more natural. We discuss the subtleties involved in the tunneling of such a de Sitter space.

  8. Euclidean action for vacuum decay in a de Sitter universe

    International Nuclear Information System (INIS)

    Balek, V.; Demetrian, M.

    2005-01-01

    The behavior of the action of the instantons describing vacuum decay in a de Sitter is investigated. For a near-to-limit instanton (a Coleman-de Luccia instanton close to some Hawking-Moss instanton) we find approximate formulas for the Euclidean action by expanding the scalar field and the metric of the instanton in the powers of the scalar field amplitude. The order of the magnitude of the correction to the Hawking-Moss action depends on the order of the instanton (the number of crossings of the barrier by the scalar field): for instantons of odd and even orders the correction is of the fourth and third order in the scalar field amplitude, respectively. If a near-to-limit instanton of the first order exists in a potential with the curvature at the top of the barrier greater than 4x(Hubble constant) 2 , which is the case if the fourth derivative of the potential at the top of the barrier is greater than some negative limit value, the action of the instanton is less than the Hawking-Moss action and, consequently, the instanton determines the outcome of the vacuum decay if no other Coleman-de Luccia instanton is admitted by the potential. A numerical study shows that for the quartic potential the physical mode of the vacuum decay is given by the Coleman-de Luccia instanton of the first order also in the region of parameters in which the potential admits two instantons of the second order

  9. Photon motion in Kerr-de Sitter spacetimes

    Energy Technology Data Exchange (ETDEWEB)

    Charbulak, Daniel; Stuchlik, Zdenek [Silesian University in Opava, Institute of Physics and Research Centre of Theoretical Physics and Astrophysics, Faculty of Philosophy and Science, Opava (Czech Republic)

    2017-12-15

    We study the general motion of photons in the Kerr-de Sitter black-hole and naked singularity spacetimes. The motion is governed by the impact parameters X, related to the axial symmetry of the spacetime, and q, related to its hidden symmetry. Appropriate 'effective potentials' governing the latitudinal and radial motion are introduced and their behavior is examined by the 'Chinese boxes' technique giving regions allowed for the motion in terms of the impact parameters. Restrictions on the impact parameters X and q are established in dependence on the spacetime parameters M, Λ, a. The motion can be of orbital type (crossing the equatorial plane, q > 0) and vortical type (tied above or below the equatorial plane, q < 0). It is shown that for negative values of q, the reality conditions imposed on the latitudinal motion yield stronger constraints on the parameter X than that following from the reality condition of the radial motion, excluding the existence of vortical motion of constant radius. The properties of the spherical photon orbits of the orbital type are determined and used along with the properties of the effective potentials as criteria of classification of the KdS spacetimes according to the properties of the motion of the photon. (orig.)

  10. High overtones of Schwarzschild-de-Sitter quasinormal spectrum

    International Nuclear Information System (INIS)

    Konoplya, R.A.; Zhidenko, A.

    2004-01-01

    We find the high overtones of gravitational and electromagnetic quasinormal spectrum of the Schwarzschild-de Sitter black hole. The calculations show that the real parts of the electromagnetic modes asymptotically approach zero. The gravitational modes show more peculiar behavior at large n: the real part oscillates as a function of imaginary even for very high overtones and these oscillations settles to some 'profile' which just repeats itself with further increasing of the overtone number n. This lets us judge that Reω is not a constant as n →∞ but rather some oscillating function. The spacing for imaginary part Imω n+1 -Imω n for electromagnetic perturbations at high n slowly approach k e as n→∞, where k e is the surface gravity. In addition we find the lower QN modes for which the values obtained with numerical methods are in a very good agreement with those obtained through the 6th order WKB technique. (author)

  11. Holography and quantum states in elliptic de Sitter space

    Energy Technology Data Exchange (ETDEWEB)

    Halpern, Illan F. [Department of Physics, University of California,Berkeley, CA, 94720 (United States); Neiman, Yasha [Perimeter Institute for Theoretical Physics,31 Caroline Street N, Waterloo, ON, N2L 2Y5 (Canada)

    2015-12-10

    We outline a program for interpreting the higher-spin dS/CFT model in terms of physics in the causal patch of a dS observer. The proposal is formulated in “elliptic” de Sitter space dS{sub 4}/ℤ{sub 2}, obtained by identifying antipodal points in dS{sub 4}. We discuss recent evidence that the higher-spin model is especially well-suited for this, since the antipodal symmetry of bulk solutions has a simple encoding on the boundary. For context, we test some other (free and interacting) theories for the same property. Next, we analyze the notion of quantum field states in the non-time-orientable dS{sub 4}/ℤ{sub 2}. We compare the physics seen by different observers, with the outcome depending on whether they share an arrow of time. Finally, we implement the marriage between higher-spin holography and observers in dS{sub 4}/ℤ{sub 2}, in the limit of free bulk fields. We succeed in deriving an observer’s operator algebra and Hamiltonian from the CFT, but not her S-matrix. We speculate on the extension of this to interacting higher-spin theory.

  12. Schwarzschild-de Sitter spacetimes, McVittie coordinates, and trumpet geometries

    Science.gov (United States)

    Dennison, Kenneth A.; Baumgarte, Thomas W.

    2017-12-01

    Trumpet geometries play an important role in numerical simulations of black hole spacetimes, which are usually performed under the assumption of asymptotic flatness. Our Universe is not asymptotically flat, however, which has motivated numerical studies of black holes in asymptotically de Sitter spacetimes. We derive analytical expressions for trumpet geometries in Schwarzschild-de Sitter spacetimes by first generalizing the static maximal trumpet slicing of the Schwarzschild spacetime to static constant mean curvature trumpet slicings of Schwarzschild-de Sitter spacetimes. We then switch to a comoving isotropic radial coordinate which results in a coordinate system analogous to McVittie coordinates. At large distances from the black hole the resulting metric asymptotes to a Friedmann-Lemaître-Robertson-Walker metric with an exponentially-expanding scale factor. While McVittie coordinates have another asymptotically de Sitter end as the radial coordinate goes to zero, so that they generalize the notion of a "wormhole" geometry, our new coordinates approach a horizon-penetrating trumpet geometry in the same limit. Our analytical expressions clarify the role of time-dependence, boundary conditions and coordinate conditions for trumpet slices in a cosmological context, and provide a useful test for black hole simulations in asymptotically de Sitter spacetimes.

  13. Perturbative S-matrix for massive scalar fields in global de Sitter space

    International Nuclear Information System (INIS)

    Marolf, Donald; Srednicki, Mark; Morrison, Ian A

    2013-01-01

    We construct a perturbative S-matrix for interacting massive scalar fields in global de Sitter space. Our S-matrix is formulated in terms of asymptotic particle states in the far past and future, taking appropriate care for light fields whose wavefunctions decay only very slowly near the de Sitter conformal boundaries. An alternative formulation expresses this S-matrix in terms of residues of poles in analytically-continued Euclidean correlators (computed in perturbation theory), making it clear that the standard Minkowski-space result is obtained in the flat-space limit. Our S-matrix transforms properly under CPT, is invariant under the de Sitter isometries and perturbative field redefinitions, and is unitary. This unitarity implies a de Sitter version of the optical theorem. We explicitly verify these properties to second order in the coupling for a general cubic interaction, including both tree- and loop-level contributions. Contrary to other statements in the literature, we find that a particle of any positive mass may decay at tree level to any number of particles, each of arbitrary positive masses. In particular, even very light fields (in the complementary series of de Sitter representations) are not protected from tree-level decays. (paper)

  14. Pair of accelerated black holes in a de Sitter background: The dS C metric

    International Nuclear Information System (INIS)

    Dias, Oscar J.C.; Lemos, Jose P.S.

    2003-01-01

    Following the work of Kinnersley and Walker for flat spacetimes, we analyzed the anti-de Sitter C metric in a previous paper. In this paper we study the de Sitter C metric (dS C metric). The C metric with a generic cosmological constant and other extra parameters was introduced by Plebanski and Demianski. When one then sets to zero some of the extra parameters, and works with a positive cosmological constant, one has the dS C metric which has been analyzed and physically interpreted by Podolsky and Griffiths. It describes a pair of accelerated black holes in the dS background with the acceleration being provided (in addition to the cosmological constant) by a strut that pushes away the two black holes or, alternatively, by a string that pulls them. We extend their analysis mainly in four directions. First, we draw the Carter-Penrose diagrams of the massless uncharged dS C metric, of the massive uncharged dS C metric and of the massive charged dS C metric. These diagrams allow us to clearly identify the presence of two dS black holes and to conclude that they cannot interact gravitationally. Second, we reexamine the embedding of the dS C metric in the 5D Minkowski spacetime and we represent the motion of the dS C metric origin in the dS 4-hyperboloid as well as the localization of the strut. Third, we comment on the physical properties of the strut that connects the two black holes. Finally, we find the range of parameters that correspond to nonextreme black holes, extreme black holes, and naked particles

  15. arXiv Spectator electric fields, de Sitter space-time and the Schwinger effect

    CERN Document Server

    Giovannini, Massimo

    2018-03-15

    During a de Sitter stage of expansion, the spectator fields of different spin are constrained by the critical density bound and by further requirements determined by their specific physical nature. The evolution of spectator electric fields in conformally flat background geometries is occasionally concocted by postulating the existence of ad hoc currents, but this apparently innocuous trick violates the second law of thermodynamics. Such a problem occurs, in particular, for those configurations (customarily employed for the analysis of the Schwinger effect in four-dimensional de Sitter backgrounds) leading to an electric energy density which is practically unaffected by the expansion of the underlying geometry. The obtained results are compared with more mundane situations where Joule heating develops in the early stages of a quasi-de Sitter phase.

  16. Temperature and entropy of Schwarzschild-de Sitter space-time

    International Nuclear Information System (INIS)

    Shankaranarayanan, S.

    2003-01-01

    In the light of recent interest in quantum gravity in de Sitter space, we investigate semiclassical aspects of four-dimensional Schwarzschild-de Sitter space-time using the method of complex paths. The standard semiclassical techniques (such as Bogoliubov coefficients and Euclidean field theory) have been useful to study quantum effects in space-times with single horizons; however, none of these approaches seem to work for Schwarzschild-de Sitter space-time or, in general, for space-times with multiple horizons. We extend the method of complex paths to space-times with multiple horizons and obtain the spectrum of particles produced in these space-times. We show that the temperature of radiation in these space-times is proportional to the effective surface gravity--the inverse harmonic sum of surface gravity of each horizon. For the Schwarzschild-de Sitter space-time, we apply the method of complex paths to three different coordinate systems--spherically symmetric, Painleve, and Lemaitre. We show that the equilibrium temperature in Schwarzschild-de Sitter space-time is the harmonic mean of cosmological and event horizon temperatures. We obtain Bogoliubov coefficients for space-times with multiple horizons by analyzing the mode functions of the quantum fields near the horizons. We propose a new definition of entropy for space-times with multiple horizons, analogous to the entropic definition for space-times with a single horizon. We define entropy for these space-times to be inversely proportional to the square of the effective surface gravity. We show that this definition of entropy for Schwarzschild-de Sitter space-time satisfies the D-bound conjecture

  17. On the de Sitter and Nariai spacetimes in a generalized theory of gravitation

    International Nuclear Information System (INIS)

    Nariai, Hidekazu.

    1985-07-01

    A possibility of obtaining the de Sitter and Nariai spacetimes in a generalized theory of gravitation (which was in succession proposed by Utiyama-DeWitt, Parker-Fulling-Hu and Gurovich-Starobinski) is examined. It is shown that the generalized theory with a suitable fixation of three parameters admit both spacetimes, just like the general theory of relativity. (author)

  18. Quasi-normal modes for Dirac fields in Kerr-Newman-de Sitter black holes

    OpenAIRE

    Iantchenko, Alexei

    2015-01-01

    We provide the full asymptotic description of the quasi-normal modes (resonances) in any strip of fixed width for Dirac fields in slowly rotating Kerr-Newman-de Sitter black holes. The resonances split in a way similar to the Zeeman effect. The method is based on the extension to Dirac operators of techniques applied by Dyatlov 2011, 2012 to the (uncharged) Kerr-de Sitter black holes. We show that the mass of the Dirac field does not have effect on the two leading terms in the expansions of r...

  19. CFT description of three-dimensional Kerr-de Sitter spacetime

    Energy Technology Data Exchange (ETDEWEB)

    Fjelstad, Jens E-mail: jens.fjelstad@kau.se; Hwang, Stephen E-mail: stephen.hwang@kau.se; Maansson, Teresia E-mail: teresia@physto.se

    2002-10-07

    We describe three-dimensional Kerr-de Sitter space using similar methods as recently applied to the BTZ black hole. A rigorous form of the classical connection between gravity in three dimensions and two-dimensional conformal field theory is employed, where the fundamental degrees of freedom are described in terms of two dependent SL(2,C) currents. In contrast to the BTZ case, however, quantization does not give the Bekenstein-Hawking entropy connected to the cosmological horizon of Kerr-de Sitter space.

  20. CFT description of three-dimensional Kerr-de Sitter spacetime

    International Nuclear Information System (INIS)

    Fjelstad, Jens; Hwang, Stephen; Maansson, Teresia

    2002-01-01

    We describe three-dimensional Kerr-de Sitter space using similar methods as recently applied to the BTZ black hole. A rigorous form of the classical connection between gravity in three dimensions and two-dimensional conformal field theory is employed, where the fundamental degrees of freedom are described in terms of two dependent SL(2,C) currents. In contrast to the BTZ case, however, quantization does not give the Bekenstein-Hawking entropy connected to the cosmological horizon of Kerr-de Sitter space

  1. On inflation and de Sitter in non-geometric string backgrounds

    Energy Technology Data Exchange (ETDEWEB)

    Hassler, Falk; Massai, Stefano [Arnold-Sommerfeld-Center for Theoretical Physics, Fakultaet fuer Physik, Ludwig-Maximilians-Universitaet Muenchen (Germany); Luest, Dieter [Arnold-Sommerfeld-Center for Theoretical Physics, Fakultaet fuer Physik, Ludwig-Maximilians-Universitaet Muenchen (Germany); Max-Planck-Institut fuer Physik, Muenchen (Germany)

    2017-10-15

    We study the problem of obtaining de Sitter and inflationary vacua from dimensional reduction of double field theory (DFT) on nongeometric string backgrounds. In this context, we consider a new class of effective potentials that admit Minkowski and de Sitter minima. We then construct a simple model of chaotic inflation arising from T-fold backgrounds and we discuss the possibility of trans-Planckian field range from nongeometric monodromies as well as the conditions required to get slow roll. (copyright 2017 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  2. Dirac equation in a de Sitter expansion for massive neutrinos from modern Kaluza-Klein theory

    International Nuclear Information System (INIS)

    Sánchez, Pablo Alejandro; Anabitarte, Mariano; Bellini, Mauricio

    2012-01-01

    Using the modern Kaluza-Klein theory of gravity (or the Induced Matter theory), we study the Dirac equation for massive neutrinos on a de Sitter background metric from a 5D Riemann-flat (and hence Ricci-flat) extended de Sitter metric, on which is defined the vacuum for test massless 1/2-spin neutral fields minimally coupled to gravity and free of any other interactions. We obtain that the effective 4D masses of the neutrinos can only take three possible values, which are related to the (static) foliation of the fifth and noncompact extra dimension.

  3. Gravitationally induced adiabatic particle production: from big bang to de Sitter

    Science.gov (United States)

    de Haro, Jaume; Pan, Supriya

    2016-08-01

    In the background of a flat homogeneous and isotropic space-time, we consider a scenario of the Universe driven by the gravitationally induced ‘adiabatic’ particle production with constant creation rate. We have shown that this Universe attains a big bang singularity in the past and at late-time it asymptotically becomes de Sitter. To clarify this model Universe, we performed a dynamical analysis and found that the Universe attains a thermodynamic equilibrium in this late de Sitter phase. Finally, for the first time, we have discussed the possible effects of ‘adiabatic’ particle creations in the context of loop quantum cosmology.

  4. Gravitationally induced adiabatic particle production: from big bang to de Sitter

    International Nuclear Information System (INIS)

    Haro, Jaume de; Pan, Supriya

    2016-01-01

    In the background of a flat homogeneous and isotropic space–time, we consider a scenario of the Universe driven by the gravitationally induced ‘adiabatic’ particle production with constant creation rate. We have shown that this Universe attains a big bang singularity in the past and at late-time it asymptotically becomes de Sitter. To clarify this model Universe, we performed a dynamical analysis and found that the Universe attains a thermodynamic equilibrium in this late de Sitter phase. Finally, for the first time, we have discussed the possible effects of ‘adiabatic’ particle creations in the context of loop quantum cosmology. (paper)

  5. Semiclassical relations and IR effects in de Sitter and slow-roll space-times

    DEFF Research Database (Denmark)

    B. Giddings, Steven; Sloth, Martin Snoager

    2010-01-01

    We calculate IR divergent graviton one-loop corrections to scalar correlators in de Sitter space, and show that the leading IR contribution may be reproduced via simple semiclassical consistency relations. One can likewise use such semiclassical relations to calculate leading IR corrections to co...... with a sharp perturbative calculation of "missing information" in Hawking radiation....

  6. A sufficient condition for de Sitter vacua in type IIB string theory

    Energy Technology Data Exchange (ETDEWEB)

    Rummel, Markus [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Westphal, Alexander [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2011-07-15

    We derive a sufficient condition for realizing meta-stable de Sitter vacua with small positive cosmological constant within type IIB string theory flux compactifications with spontaneously broken supersymmetry. There are a number of 'lamp post' constructions of de Sitter vacua in type IIB string theory and supergravity. We show that one of them - the method of 'Kaehler uplifting' by F-terms from an interplay between non-perturbative effects and the leading {alpha}'-correction - allows for a more general parametric understanding of the existence of de Sitter vacua. The result is a condition on the values of the flux induced superpotential and the topological data of the Calabi-Yau compactification, which guarantees the existence of a meta-stable de Sitter vacuum if met. Our analysis explicitly includes the stabilization of all moduli, i.e. the Kaehler, dilaton and complex structure moduli, by the interplay of the leading perturbative and non-perturbative effects at parametrically large volume. (orig.)

  7. Gauge-invariant metric fluctuations from NKK theory of gravity: de Sitter expansion

    International Nuclear Information System (INIS)

    Aguilar, Jose Edgar Madriz; Anabitarte, Mariano; Bellini, Mauricio

    2006-01-01

    In this Letter we study gauge-invariant metric fluctuations from a noncompact Kaluza-Klein (NKK) theory of gravity in de Sitter expansion. We recover the well-known result δρ/ρ∼2Φ, obtained from the standard 4D semiclassical approach to inflation. The spectrum for these fluctuations should be dependent of the fifth (spatial-like) coordinate

  8. Quantum Scalar Corrections to the Gravitational Potentials on de Sitter Background

    NARCIS (Netherlands)

    Park, Sohyun; Prokopec, Tomislav; Woodard, R. P.

    We employ the graviton self-energy induced by a massless, minimally coupled (MMC) scalar on de Sitter background to compute the quantum corrections to the gravitational potentials of a static point particle with a mass $M$. The Schwinger-Keldysh formalism is used to derive real and causal effective

  9. A Spacetime Foam Approach to the Schwarzschild-de Sitter Entropy

    Directory of Open Access Journals (Sweden)

    Remo Garattini

    2000-03-01

    Full Text Available The entropy for a black hole in a de Sitter space is approached within the framework of spacetime foam. A simple model made by N wormholes in a semiclassical approximation, is taken under examination to compute the entropy for such a case. An extension to the extreme case when the black hole and cosmological horizons are equal is discussed.

  10. The de Sitter spacetime as an attractor solution in fourth-order gravity

    International Nuclear Information System (INIS)

    Schmidt, H.-J.

    1988-01-01

    We investigate the general vacuum solution of fourth-order gravity, and include the Bach tensor. For L 2 = 1.3μR 2 + 1/2αC 2 the expanding de Sitter spacetime is an attractor in the set of axially symmetric Bianchi type-I models if and only if αμ ≤ 0 or α > 4μ holds. It will be argued that this result holds true for a large class of inhomogeneous models. As a byproduct, a new closed-form cosmological solution, is obtained. It is also shown that the de Sitter spacetime is an attractor for the Bach-Einstein gravity with a minimally coupled scalar field φ. Specialised to Einstein gravity (i.e. α = 0 above) this conformal equivalence remains a non-trivial one. (author)

  11. Revealing infinite derivative gravity's true potential: The weak-field limit around de Sitter backgrounds

    Science.gov (United States)

    Edholm, James

    2018-03-01

    General Relativity is known to produce singularities in the potential generated by a point source. Our universe can be modeled as a de Sitter (dS) metric and we show that ghost-free infinite derivative gravity (IDG) produces a nonsingular potential around a dS background, while returning to the GR prediction at large distances. We also show that although there are an apparently infinite number of coefficients in the theory, only a finite number actually affect the predictions. By writing the linearized equations of motion in a simplified form, we find that at distances below the Hubble length scale, the difference between the IDG potential around a flat background and around a de Sitter background is negligible.

  12. Restoration of the covariant gauge α in the initial field of gravity in de Sitter spacetime

    Energy Technology Data Exchange (ETDEWEB)

    Cheong, Lee Yen; Yan, Chew Xiao [Department of Fundamental and Applied Sciences, Universiti Teknologi Petronas, Bandar Seri Iskandar, Tronoh 31750, Perak (Malaysia)

    2014-03-05

    The gravitational field generated by a mass term and the initial surface through covariant retarded Green's function for linearized gravity in de Sitter spacetime was studied recently [4, 5] with the covariant gauges set to β = 2/3 and α = 5/3. In this paper we extend the work to restore the gauge parameter α in the field coming from the initial data using the method of shifting the parameter. The α terms in the initial field cancels exactly with the one coming from the source term. Consequently, the correct field configuration, with two equal mass points moving in its geodesic, one located at the North pole and another one located at the South pole, is reproduced in the whole manifold of de Sitter spacetime.

  13. arXiv On classical de Sitter and Minkowski solutions with intersecting branes

    CERN Document Server

    Andriot, David

    2018-03-09

    Motivated by the connection of string theory to cosmology or particle physics, we study solutions of type II supergravities having a four-dimensional de Sitter or Minkowski space-time, with intersecting D$_{p}$ -branes and orientifold O$_{p}$ -planes. Only few such solutions are known, and we aim at a better characterisation. Modulo a few restrictions, we prove that there exists no classical de Sitter solution for any combination of D$_{3}$/O$_{3}$ and D$_{7}$/O$_{7}$, while we derive interesting constraints for intersecting D$_{5}$/O$_{5}$ or D$_{6}$/O$_{6}$, or combinations of D$_{4}$/O$_{4}$ and D$_{8}$/O$_{8}$. Concerning classical Minkowski solutions, we understand some typical features, and propose a solution ansatz. Overall, a central information appears to be the way intersecting D$_{p}$ /O$_{p}$ overlap each other, a point we focus on.

  14. de Sitter-invariant special relativity and the dark energy problem

    Science.gov (United States)

    Araujo, A.; López, D. F.; Pereira, J. G.

    2017-06-01

    The replacement of the Poincaré-invariant Einstein special relativity by a de Sitter-invariant special relativity produces concomitant changes in all relativistic theories, including general relativity. A crucial change in the latter is that both the background de Sitter curvature and the gravitational dynamical curvature turns out to be included in a single curvature tensor. This means that the cosmological term Λ no longer explicitly appears in Einstein equation, and is consequently not restricted to be constant. In this paper, the Newtonian limit of such theory is obtained, and the ensuing Newtonian Friedmann equations are shown to provide a good account of the dark energy content of the present-day universe.

  15. Classification of Kerr-de Sitter-like spacetimes with conformally flat \\mathscr{I}

    Science.gov (United States)

    Mars, Marc; Paetz, Tim-Torben; Senovilla, José M. M.

    2017-05-01

    We provide a classification of Λ >0 -vacuum spacetimes which admit a Killing vector field with respect to which the associated ‘Mars-Simon tensor’ (MST) vanishes and have a conformally flat {{\\mathscr{I}}-} (or {{\\mathscr{I}}+} ). To that end, we also give a complete classification of conformal Killing vector fields on the 3-sphere {{{S}}3} up to Möbius transformations shedding light on the two fundamental constants that characterize the family of Kerr-de Sitter-like spacetimes, which turn out to be well-defined geometrical invariants. The topology of \\mathscr{I} is determined in every case, and a characterization result at \\mathscr{I} of the Kerr-de Sitter family presented. Preprint UWThPh-2016-20.

  16. Evidence for a bound on the lifetime of de Sitter space

    International Nuclear Information System (INIS)

    Freivogel, Ben; Lippert, Matthew

    2008-01-01

    Recent work has suggested a surprising new upper bound on the lifetime of de Sitter vacua in string theory. The bound is parametrically longer than the Hubble time but parametrically shorter than the recurrence time. We investigate whether the bound is satisfied in a particular class of de Sitter solutions, the KKLT vacua. Despite the freedom to make the supersymmetry breaking scale exponentially small, which naively would lead to extremely stable vacua, we find that the lifetime is always less than about exp(10 22 ) Hubble times, in agreement with the proposed bound. This result, however, is contingent on several estimates and assumptions; in particular, we rely on a conjectural upper bound on the Euler number of the Calabi-Yau fourfolds used in KKLT compactifications.

  17. Thermodynamics of the Schwarzschild-de Sitter black hole: Thermal stability of the Nariai black hole

    International Nuclear Information System (INIS)

    Myung, Yun Soo

    2008-01-01

    We study the thermodynamics of the Schwarzschild-de Sitter black hole in five dimensions by introducing two temperatures based on the standard and Bousso-Hawking normalizations. We use the first-law of thermodynamics to derive thermodynamic quantities. The two temperatures indicate that the Nariai black hole is thermodynamically unstable. However, it seems that black hole thermodynamics favors the standard normalization and does not favor the Bousso-Hawking normalization

  18. On the covariant gauge {alpha} of the linearized gravity in de Sitter spacetime

    Energy Technology Data Exchange (ETDEWEB)

    Cheong, Lee Yen [Department of Fundamental and Applied Science Universiti Teknologi Petronas, Bandar Seri Iskandar, 31750 Tronoh, Perak (Malaysia)

    2012-09-26

    In previous work, we studied the linearized gravity with covariant gauge {beta}= 2/3 and {alpha}= 5/3. It was found that the sum of the source and initial contributions reproduces the correct field configuration over the whole de Sitter spacetime. In this paper, we extend this work to generalizing the linearized gravitational field in an arbitrary value of the gauge parameter {alpha} but the gauge parameter {beta} remains the same.

  19. PURE STATE ENTANGLEMENT ENTROPY IN NONCOMMUTATIVE 2D DE SITTER SPACE TIME

    Directory of Open Access Journals (Sweden)

    M.F Ghiti

    2014-12-01

    Full Text Available Using the general modified field equation, a general noncommutative Klein-Gordon equation up to the second order of the noncommutativity parameter is derived in the context of noncommutative 2D De Sitter space-time. Using Bogoliubov coefficients and a special technics called conformal time; the boson-antiboson pair creation density is determined. The Von Neumann boson-antiboson pair creation quantum entanglement entropy is presented to compute the entanglement between the modes created presented.

  20. Separability and Killing tensors in Kerr-Taub-NUT-de Sitter metrics in higher dimensions

    International Nuclear Information System (INIS)

    Chong, Z.-W.; Gibbons, G.W.; Lue, H.; Pope, C.N.

    2005-01-01

    A generalisation of the four-dimensional Kerr-de Sitter metrics to include a NUT charge is well known, and is included within a class of metrics obtained by Plebanski. In this Letter, we study a related class of Kerr-Taub-NUT-de Sitter metrics in arbitrary dimensions D>=6, which contain three non-trivial continuous parameters, namely the mass, the NUT charge, and a (single) angular momentum. We demonstrate the separability of the Hamilton-Jacobi and wave equations, we construct a closely-related rank-2 Stackel-Killing tensor, and we show how the metrics can be written in a double Kerr-Schild form. Our results encompass the case of the Kerr-de Sitter metrics in arbitrary dimension, with all but one rotation parameter vanishing. Finally, we consider the real Euclidean-signature continuations of the metrics, and show how in a limit they give rise to certain recently-obtained complete non-singular compact Einstein manifolds

  1. Inflation including collapse of the wave function: the quasi-de Sitter case

    Energy Technology Data Exchange (ETDEWEB)

    Leon, Gabriel [Universidad de Buenos Aires, Ciudad Universitaria-PabI, Departamento de Fisica, Facultad de Ciencias Exactas y Naturales, Buenos Aires (Argentina); Landau, Susana J. [Universidad de Buenos Aires y IFIBA, CONICET, Ciudad Universitaria-PabI, Departamento de Fisica, Facultad de Ciencias Exactas y Naturales, Buenos Aires (Argentina); Piccirilli, Maria Pia [Universidad Nacional de La Plata, Grupo de Astrofisica, Relatividad y Cosmologia, Facultad de Ciencias Astronomicas y Geofisicas, Pcia de Buenos Aires (Argentina)

    2015-08-15

    The precise physical mechanism describing the emergence of the seeds of cosmic structure from a perfect isotropic and homogeneous universe has not been fully explained by the standard version of inflationary models. To handle this shortcoming, D. Sudarsky and collaborators have developed a proposal: the self-induced collapse hypothesis. In this scheme, the objective collapse of the inflaton wave function is responsible for the emergence of inhomogeneity and anisotropy at all scales. In previous papers, the proposal was developed with an almost exact de Sitter space-time approximation for the background that led to a perfect scale-invariant power spectrum. In the present article, we consider a full quasi-de Sitter expansion and calculate the primordial power spectrum for three different choices of the self-induced collapse. The consideration of a quasi-de Sitter background allows us to distinguish departures from an exact scale-invariant power spectrum that are due to the inclusion of the collapse hypothesis. These deviations are also different from the prediction of standard inflationary models with a running spectral index. A comparison with the primordial power spectrum and the CMB temperature fluctuation spectrum preferred by the latest observational data is also discussed. From the analysis performed in this work, it follows that most of the collapse schemes analyzed in this paper are viable candidates to explain the present observations of the CMB fluctuation spectrum. (orig.)

  2. Inflation including collapse of the wave function: the quasi-de Sitter case

    International Nuclear Information System (INIS)

    Leon, Gabriel; Landau, Susana J.; Piccirilli, Maria Pia

    2015-01-01

    The precise physical mechanism describing the emergence of the seeds of cosmic structure from a perfect isotropic and homogeneous universe has not been fully explained by the standard version of inflationary models. To handle this shortcoming, D. Sudarsky and collaborators have developed a proposal: the self-induced collapse hypothesis. In this scheme, the objective collapse of the inflaton wave function is responsible for the emergence of inhomogeneity and anisotropy at all scales. In previous papers, the proposal was developed with an almost exact de Sitter space-time approximation for the background that led to a perfect scale-invariant power spectrum. In the present article, we consider a full quasi-de Sitter expansion and calculate the primordial power spectrum for three different choices of the self-induced collapse. The consideration of a quasi-de Sitter background allows us to distinguish departures from an exact scale-invariant power spectrum that are due to the inclusion of the collapse hypothesis. These deviations are also different from the prediction of standard inflationary models with a running spectral index. A comparison with the primordial power spectrum and the CMB temperature fluctuation spectrum preferred by the latest observational data is also discussed. From the analysis performed in this work, it follows that most of the collapse schemes analyzed in this paper are viable candidates to explain the present observations of the CMB fluctuation spectrum. (orig.)

  3. Hydrogen-like spectrum of spontaneously created brane universes with de-Sitter ground state

    Science.gov (United States)

    Davidson, Aharon

    2018-05-01

    Unification of Randall-Sundrum and Regge-Teitelboim brane cosmologies gives birth to a serendipitous Higgs-deSitter interplay. A localized Dvali-Gabadadze-Porrati scalar field, governed by a particular (analytically derived) double-well quartic potential, becomes a mandatory ingredient for supporting a deSitter brane universe. When upgraded to a general Higgs potential, the brane surface tension gets quantized, resembling a Hydrogen atom spectrum, with deSitter universe serving as the ground state. This reflects the local/global structure of the Euclidean manifold: From finite energy density no-boundary initial conditions, via a novel acceleration divide filter, to exact matching conditions at the exclusive nucleation point. Imaginary time periodicity comes as a bonus, with the associated Hawking temperature vanishing at the continuum limit. Upon spontaneous creation, while a finite number of levels describe universes dominated by a residual dark energy combined with damped matter oscillations, an infinite tower of excited levels undergo a Big Crunch.

  4. Detecting the Curvature of de Sitter Universe with Two Entangled Atoms.

    Science.gov (United States)

    Tian, Zehua; Wang, Jieci; Jing, Jiliang; Dragan, Andrzej

    2016-10-12

    Casimir-Polder interaction arises from the vacuum fluctuations of quantum field that depend on spacetime curvature and thus is spacetime-dependent. Here we show how to use the resonance Casimir-Polder interaction (RCPI) between two entangled atoms to detect spacetime curvature. We find that the RCPI of two static entangled atoms in the de Sitter-invariant vacuum depends on the de Sitter spacetime curvature relevant to the temperature felt by the static observer. It is characterized by a 1/L 2 power law decay when beyond a characteristic length scale associated to the breakdown of a local inertial description of the two-atom system. However, the RCPI of the same setup embedded in a thermal bath in the Minkowski universe is temperature-independent and is always characterized by a 1/L power law decay. Therefore, although a single static atom in the de Sitter-invariant vacuum responds as if it were bathed in thermal radiation in a Minkowski universe, using the distinct difference between RCPI of two entangled atoms one can in principle distinguish these two universes.

  5. Dingle and de Sitter Against the Metaphysicians, or Two Ways to Keep Modern Cosmology Physical

    Science.gov (United States)

    Gale, George

    It would be hard to find two more radically different personalities than the irascible Herbert Dingle and the courtly Willem de Sitter. Yet, when it came to their philosophy of science, these two otherwise-so-different men were united against a common enemy, those they both called the "metaphysicians." Right from 1917, de Sitter attempted always to keep cosmology tightly bound to real observations made upon a real world. In Kosmos, written near the end of his life, he re-affirms most strongly his principle that "there is nothing an orthodox physicist abhors more than metaphysics." Dingle, for his part, accepts early on the positivist use of the verifiability principle to eliminate metaphysics from science, and continuously wields the principle as a weapon against those errant cosmologists who would sacrifice science for a sort of mysticism. Both men reject the strict and literal use of the term "universe," and for the same reasons: there is no observation, no verification, of statements containing that term. Both men reject the "cosmological principle" as Milne and others use it, on the grounds, as de Sitter puts it, that "we have . . . no means of communicating with other observers, situated on faraway stars." Eddington, although always closely associated with de Sitter personally, comes in for his own fine share of criticism. After de Sitter's death, Dingle carried on the battle alone, always on the bases that he and de Sitter had earlier established. The two peaks in Dingle's long struggle were the notorious 1937 controversy in the pages of Nature, a nasty dogfight which managed to involve almost every single important physicist in Britain; thirteen years later, the long war with the metaphysicians ended with the pyrrhic victory of Dingle's Royal Astronomical Society Presidential Address' invective against the latest and greatest metaphysical creation, Bondi's steady state universe theory. In the end, however, it would be a mistake to believe that the campaign

  6. Greybody factors for a spherically symmetric Einstein-Gauss-Bonnet-de Sitter black hole

    Science.gov (United States)

    Zhang, Cheng-Yong; Li, Peng-Cheng; Chen, Bin

    2018-02-01

    We study the greybody factors of the scalar fields in spherically symmetric Einstein-Gauss-Bonnet-de Sitter black holes in higher dimensions. We derive the greybody factors analytically for both minimally and nonminimally coupled scalar fields. Moreover, we discuss the dependence of the greybody factor on various parameters including the angular momentum number, the nonminimally coupling constant, the spacetime dimension, the cosmological constant, and the Gauss-Bonnet coefficient in detail. We find that the nonminimal coupling may suppress the greybody factor and the Gauss-Bonnet coupling could enhance it, but they both suppress the energy emission rate of Hawking radiation.

  7. The flux-scaling scenario. De Sitter uplift and axion inflation

    Energy Technology Data Exchange (ETDEWEB)

    Blumenhagen, Ralph; Damian, Cesar; Herschmann, Daniela; Sun, Rui [Max-Planck-Institut fuer Physik (Werner-Heisenberg-Institut), Muenchen (Germany); Font, Anamaria [Departamento de Fisica, Centro de Fisica Teorica y Computacional, Facultad de Ciencias, Universidad Central de Venezuela, Caracas (Venezuela, Bolivarian Republic of)

    2016-06-15

    Non-geometric flux-scaling vacua provide promising starting points to realize axion monodromy inflation via the F-term scalar potential. We show that these vacua can be uplifted to Minkowski and de Sitter by adding an D3-brane or a D-term containing geometric and non-geometric fluxes. These uplifted non-supersymmetric models are analyzed with respect to their potential to realize axion monodromy inflation self-consistently. Admitting rational values of the fluxes, we construct examples with the required hierarchy of mass scales. (copyright 2016 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  8. The flux-scaling scenario. De Sitter uplift and axion inflation

    International Nuclear Information System (INIS)

    Blumenhagen, Ralph; Damian, Cesar; Herschmann, Daniela; Sun, Rui; Font, Anamaria

    2016-01-01

    Non-geometric flux-scaling vacua provide promising starting points to realize axion monodromy inflation via the F-term scalar potential. We show that these vacua can be uplifted to Minkowski and de Sitter by adding an D3-brane or a D-term containing geometric and non-geometric fluxes. These uplifted non-supersymmetric models are analyzed with respect to their potential to realize axion monodromy inflation self-consistently. Admitting rational values of the fluxes, we construct examples with the required hierarchy of mass scales. (copyright 2016 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  9. Indications of de Sitter spacetime from classical sequential growth dynamics of causal sets

    International Nuclear Information System (INIS)

    Ahmed, Maqbool; Rideout, David

    2010-01-01

    A large class of the dynamical laws for causal sets described by a classical process of sequential growth yields a cyclic universe, whose cycles of expansion and contraction are punctuated by single 'origin elements' of the causal set. We present evidence that the effective dynamics of the immediate future of one of these origin elements, within the context of the sequential growth dynamics, yields an initial period of de Sitter-like exponential expansion, and argue that the resulting picture has many attractive features as a model of the early universe, with the potential to solve some of the standard model puzzles without any fine-tuning.

  10. A Review on the Cosmology of the de Sitter Horndeski Models

    Directory of Open Access Journals (Sweden)

    Nelson J. Nunes

    2017-03-01

    Full Text Available We review the most general scalar-tensor cosmological models with up to second-order derivatives in the field equations that have a fixed spatially flat de Sitter critical point independent of the material content or vacuum energy. This subclass of the Horndeski Lagrangian is capable of dynamically adjusting any value of the vacuum energy of the matter fields at the critical point. We present the cosmological evolution of the linear models and the non-linear models with shift symmetry. We come to the conclusion that the shift symmetric non-linear models can deliver a viable background compatible with current observations.

  11. New tortoise coordinate transformation and Hawking's radiation in de Sitter space

    Science.gov (United States)

    Ibohal, N.; Ibungochouba, T.

    2013-01-01

    Hawking's radiation effect of Klein-Gordon equation, Dirac particles and Maxwell's electromagnetic fields in the non-stationary rotating de Sitter cosmological space-time is investigated by using a new method of generalized tortoise coordinate transformation. It is found that the new transformation produces constant additional terms in the expressions of the surface gravities and the Hawking's temperatures. If the constant terms are set to zero, then the surface gravities and Hawking's temperatures will be equal to those obtained from the old generalized tortoise coordinate transformations. This shows that the new transformations are more reasonable. The Fermionic spectrum of Dirac particles displays a new spin-rotation coupling effect.

  12. Holographic Thermalization in Gauss-Bonnet Gravity with de Sitter Boundary

    CERN Document Server

    Zhang, Shao-Jun; Abdalla, Elcio; Papantonopoulos, Eleftherios

    2015-01-01

    We introduce higher-derivative Gauss-Bonnet correction terms in the gravity sector and we relate the modified gravity theory in the bulk to the strongly coupled quantum field theory on a de Sitter boundary. We study the process of holographic thermalization by examining three non-local observables, the two-point function, the Wilson loop and the holographic entanglement entropy. We study the time evolution of these three observables and we find that the modification of the gravity side with the Gauss-Bonnet correction terms influences the saturation time to reach thermal equilibrium with the dominant effect given by the holographic entanglement entropy since it contains more bulk information.

  13. Exact Solution of Klein-Gordon and Dirac Equations with Snyder-de Sitter Algebra

    Science.gov (United States)

    Merad, M.; Hadj Moussa, M.

    2018-01-01

    In this paper, we present the exact solution of the (1+1)-dimensional relativistic Klein-Gordon and Dirac equations with linear vector and scalar potentials in the framework of deformed Snyder-de Sitter model. We introduce some changes of variables, we show that a one-dimensional linear potential for the relativistic system in a space deformed can be equivalent to the trigonometric Rosen-Morse potential in a regular space. In both cases, we determine explicitly the energy eigenvalues and their corresponding eigenfunctions expressed in terms of Romonovski polynomials. The limiting cases are analyzed for α 1 and α 2 → 0 and are compared with those of literature.

  14. Vacuum state of the Dirac field in de Sitter space and entanglement entropy

    Energy Technology Data Exchange (ETDEWEB)

    Kanno, Sugumi [Department of Theoretical Physics and History of Science,University of the Basque Country,48080 Bilbao (Spain); IKERBASQUE, Basque Foundation for Science,Maria Diaz de Haro 3, 48013, Bilbao (Spain); Sasaki, Misao [Center for Gravitational Physics,Yukawa Institute for Theoretical Physics, Kyoto University,Kyoto 606-8502 (Japan); Tanaka, Takahiro [Department of Physics, Kyoto University,Kyoto 606-8502 (Japan); Center for Gravitational Physics,Yukawa Institute for Theoretical Physics, Kyoto University,Kyoto 606-8502 (Japan)

    2017-03-13

    We compute the entanglement entropy of a free massive Dirac field between two causally disconnected open charts in de Sitter space. We first derive the Bunch-Davies vacuum mode functions of the Dirac field. We find there exists no supercurvature mode for the Dirac field. We then give the Bogoliubov transformation between the Bunch-Davies vacuum and the open chart vacua that makes the reduced density matrix diagonal. We find that the Dirac field becomes more entangled than a scalar field as m{sup 2}/H{sup 2} becomes small, and the difference is maximal in the massless limit.

  15. Null geodesics and embedding diagrams of the interior Schwarzschild--de Sitter spacetimes with uniform density

    International Nuclear Information System (INIS)

    Stuchlik, Zdenek; Hledik, Stanislav; Soltes, Jiri; Ostgaard, Erlend

    2001-01-01

    Null geodesics and embedding diagrams of central planes in the ordinary space geometry and the optical reference geometry of the interior Schwarzschild--de Sitter spacetimes with uniform density are studied. For completeness, both positive and negative values of the cosmological constant are considered. The null geodesics are restricted to the central planes of these spacetimes, and their properties can be reflected by an 'effective potential.' If the interior spacetime is extremely compact, the effective potential has a local maximum corresponding to a stable circular null geodesic around which bound null geodesics are concentrated. The upper limit on the size of the interior spacetimes containing bound null geodesics is R=3M, independently of the value of the cosmological constant. The embedding diagrams of the central planes of the ordinary geometry into three-dimensional Euclidean space are well defined for the complete interior of all spacetimes with a repulsive cosmological constant, but the planes cannot be embedded into the Euclidean space in the case of spacetimes with subcritical values of an attractive cosmological constant. On the other hand, the embedding diagrams of the optical geometry are well defined for all of the spacetimes, and the turning points of these diagrams correspond to the radii of the circular null geodesics. All the embedding diagrams, for both the ordinary and optical geometry, are smoothly matched to the corresponding embedding diagrams of the external vacuum Schwarzschild--de Sitter spacetimes

  16. Entangled de Sitter from stringy axionic Bell pair I: an analysis using Bunch-Davies vacuum

    Science.gov (United States)

    Choudhury, Sayantan; Panda, Sudhakar

    2018-01-01

    In this work, we study the quantum entanglement and compute entanglement entropy in de Sitter space for a bipartite quantum field theory driven by an axion originating from Type IIB string compactification on a Calabi-Yau three fold (CY^3) and in the presence of an NS5 brane. For this computation, we consider a spherical surface S^2, which divides the spatial slice of de Sitter (dS_4) into exterior and interior sub-regions. We also consider the initial choice of vacuum to be Bunch-Davies state. First we derive the solution of the wave function of the axion in a hyperbolic open chart by constructing a suitable basis for Bunch-Davies vacuum state using Bogoliubov transformation. We then derive the expression for density matrix by tracing over the exterior region. This allows us to compute the entanglement entropy and Rényi entropy in 3+1 dimension. Furthermore, we quantify the UV-finite contribution of the entanglement entropy which contain the physics of long range quantum correlations of our expanding universe. Finally, our analysis complements the necessary condition for generating non-vanishing entanglement entropy in primordial cosmology due to the axion.

  17. Solutions to Yang-Mills Equations on Four-Dimensional de Sitter Space.

    Science.gov (United States)

    Ivanova, Tatiana A; Lechtenfeld, Olaf; Popov, Alexander D

    2017-08-11

    We consider pure SU(2) Yang-Mills theory on four-dimensional de Sitter space dS_{4} and construct a smooth and spatially homogeneous magnetic solution to the Yang-Mills equations. Slicing dS_{4} as R×S^{3}, via an SU(2)-equivariant ansatz, we reduce the Yang-Mills equations to ordinary matrix differential equations and further to Newtonian dynamics in a double-well potential. Its local maximum yields a Yang-Mills solution whose color-magnetic field at time τ∈R is given by B[over ˜]_{a}=-1/2I_{a}/(R^{2}cosh^{2}τ), where I_{a} for a=1, 2, 3 are the SU(2) generators and R is the de Sitter radius. At any moment, this spatially homogeneous configuration has finite energy, but its action is also finite and of the value -1/2j(j+1)(2j+1)π^{3} in a spin-j representation. Similarly, the double-well bounce produces a family of homogeneous finite-action electric-magnetic solutions with the same energy. There is a continuum of other solutions whose energy and action extend down to zero.

  18. Nonequilibrium Dynamics of the σ-Model Modes on the de Sitter Space

    Directory of Open Access Journals (Sweden)

    Ion V. Vancea

    2017-01-01

    Full Text Available The two-dimensional σ-model with the de Sitter target space is locally canonic in the north pole diamond of the Penrose diagram in the cosmological gauge. The left and right moving modes on the cylindrical base space are entangled among themselves and interact with the de Sitter metric. Firstly, we show that the untangled oscillators can be obtained from the entangled operators by applying a set of Bogoliubov transformations constrained by the requirement that the partial evolution generator be diagonal. Secondly, we determine the nonequilibrium dynamics of the untangled modes in the nonequilibrium thermofield dynamics formalism. The thermal modes are represented as thermal doublet oscillators that satisfy partial evolution equations of Heisenberg-type. From these we compute the local free one-body propagator of an arbitrary mode between two times. Thirdly, we discuss the field representation of the thermal modes. We show that there is a set of thermal doublet fields that satisfy the equal time canonical commutation relations, are solutions to the σ-model equations of motion, and can be decomposed in terms of thermal doublet oscillators. Finally, we construct a local partial evolution functional of Hamilton-like form for the thermal doublet fields.

  19. $O(N)$ model in Euclidean de Sitter space: beyond the leading infrared approximation

    CERN Document Server

    Nacir, Diana López; Trombetta, Leonardo G

    2016-01-01

    We consider an $O(N)$ scalar field model with quartic interaction in $d$-dimensional Euclidean de Sitter space. In order to avoid the problems of the standard perturbative calculations for light and massless fields, we generalize to the $O(N)$ theory a systematic method introduced previously for a single field, which treats the zero modes exactly and the nonzero modes perturbatively. We compute the two-point functions taking into account not only the leading infrared contribution, coming from the self-interaction of the zero modes, but also corrections due to the interaction of the ultraviolet modes. For the model defined in the corresponding Lorentzian de Sitter spacetime, we obtain the two-point functions by analytical continuation. We point out that a partial resummation of the leading secular terms (which necessarily involves nonzero modes) is required to obtain a decay at large distances for massless fields. We implement this resummation along with a systematic double expansion in an effective coupling c...

  20. De Sitter vacua from a D-term generated racetrack potential in hypersurface Calabi-Yau compactifications

    Energy Technology Data Exchange (ETDEWEB)

    Braun, Andreas P. [Rudolph Peierls Centre for Theoretical Physics, University of Oxford,1 Keble Road, Oxford, OX1 3NP (United Kingdom); Mathematical Institute, University of Oxford, Woodstock Road,Oxford, OX2 6GG (United Kingdom); Rummel, Markus [Rudolph Peierls Centre for Theoretical Physics, University of Oxford,1 Keble Road, Oxford, OX1 3NP (United Kingdom); Sumitomo, Yoske [High Energy Accelerator Research Organization, KEK,1-1 Oho, Tsukuba, Ibaraki 305-0801 (Japan); Valandro, Roberto [Dipartimento di Fisica dell’Università di Trieste,Strada Costiera 11, 34151 Trieste (Italy); INFN - Sezione di Trieste,Via Valerio 2, 34127 Trieste (Italy); ICTP,Strada Costiera 11, 34151 Trieste (Italy)

    2015-12-04

    In http://dx.doi.org/10.1007/JHEP01(2015)015 a mechanism to fix the closed string moduli in a de Sitter minimum was proposed: a D-term potential generates a linear relation between the volumes of two rigid divisors which in turn produces at lower energies a race-track potential with de Sitter minima at exponentially large volume. In this paper, we systematically search for implementations of this mechanism among all toric Calabi-Yau hypersurfaces with h{sup 1,1}≤4 from the Kreuzer-Skarke list. For these, topological data can be computed explicitly allowing us to find the subset of three-folds which have two rigid toric divisors that do not intersect each other and that are orthogonal to h{sup 1,1}−2 independent four-cycles. These manifolds allow to find D7-brane configurations compatible with the de Sitter uplift mechanism and we find an abundance of consistent choices of D7-brane fluxes inducing D-terms leading to a de Sitter minimum. Finally, we work out a couple of models in detail, checking the global consistency conditions and computing the value of the potential at the minimum.

  1. Charged de Sitter-like black holes: quintessence-dependent enthalpy and new extreme solutions

    Energy Technology Data Exchange (ETDEWEB)

    Azreg-Ainou, Mustapha [Baskent University, Faculty of Engineering, Ankara (Turkey)

    2015-01-01

    We consider Reissner-Nordstroem black holes surrounded by quintessence where both a non-extremal event horizon and a cosmological horizon exist besides an inner horizon (-1 ≤ ω < -1/3). We determine new extreme black hole solutions that generalize the Nariai horizon to asymptotically de Sitter-like solutions for any order relation between the squares of the charge q{sup 2} and the mass parameter M{sup 2} provided q{sup 2} remains smaller than some limit, which is larger than M{sup 2}. In the limit case q{sup 2} = 9ω{sup 2}M{sup 2}/(9ω{sup 2}-1), we derive the general expression of the extreme cosmo-blackhole, where the three horizons merge, and we discuss some of its properties.We also show that the endpoint of the evaporation process is independent of any order relation between q{sup 2} and M{sup 2}. The Teitelboim energy and the Padmanabhan energy are related by a nonlinear expression and are shown to correspond to different ensembles. We also determine the enthalpy H of the event horizon, as well as the effective thermodynamic volume which is the conjugate variable of the negative quintessential pressure, and show that in general the mass parameter and the Teitelboim energy are different from the enthalpy and internal energy; only in the cosmological case, that is, for Reissner-Nordstroem-de Sitter black hole we have H = M. Generalized Smarr formulas are also derived. It is concluded that the internal energy has a universal expression for all static charged black holes, with possibly a variable mass parameter, but it is not a suitable thermodynamic potential for static-black-hole thermodynamics if M is constant. It is also shown that the reverse isoperimetric inequality holds. We generalize the results to the case of the Reissner-Nordstroem-de Sitter black hole surrounded by quintessence with two physical constants yielding two thermodynamic volumes. (orig.)

  2. Holographic thermalization in charged dilaton anti-de Sitter spacetime

    Directory of Open Access Journals (Sweden)

    Shao-Jun Zhang

    2015-07-01

    Full Text Available We study holographic thermalization in spacetimes with a chemical potential and a non-trivial dilaton field. Three non-local observables are used to probe the whole process and investigate the effect of the ratio of the chemical potential over temperature χ and the dilaton-Maxwell coupling constant α. It is found that the saturation time is not always a monotonically increasing function of χ, the situation depends on α. When 0≤α≤1, larger χ yields longer saturation time, while for α>1, the situation becomes more complex. More interesting, we found that although α indeed has influence on the whole thermalization process, it nearly does not affect the saturation time, which indicates the universality of the saturation time for the dual one-parameter field theories.

  3. Expanding plasmas from anti de Sitter black holes

    Energy Technology Data Exchange (ETDEWEB)

    Camilo, Giancarlo [Instituto de Fisica, Universidade de Sao Paulo, Departamento de Fisica Matematica, Sao Paulo (Brazil)

    2016-12-15

    We introduce a new foliation of AdS{sub 5} black holes such that the conformal boundary takes the form of a 4-dimensional FLRW spacetime with scale factor a(t). The foliation employs Eddington-Finkelstein-like coordinates and is applicable to a large class of AdS black holes, supported by matter fields or not, considerably extending previous efforts in the literature. We argue that the holographic dual picture of a CFT plasma on a FLRW background provides an interesting prototype to study the nonequilibrium dynamics of expanding plasmas and use holographic renormalization to extract the renormalized energy-momentum tensor of the dual plasma. We illustrate the procedure for three black holes of interest, namely AdS-Schwarzschild, AdS-Gauss-Bonnet, and AdS-Reissner-Nordstroem. For the latter, as a by-product, we show that the nonequilibrium dynamics of a CFT plasma subject to a quench in the chemical potential (i.e., a time-dependent chemical potential) resembles a cosmological evolution with the scale factor a(t) being inversely related to the quench profile μ(t). (orig.)

  4. Configurational entropy of anti-de Sitter black holes

    Science.gov (United States)

    Braga, Nelson R. F.; da Rocha, Roldão

    2017-04-01

    Recent studies indicate that the configurational entropy is an useful tool to investigate the stability and (or) the relative dominance of states for diverse physical systems. Recent examples comprise the connection between the variation of this quantity and the relative fraction of light mesons and glueballs observed in hadronic processes. Here we develop a technique for defining a configurational entropy for an AdS-Schwarzschild black hole. The achieved result corroborates consistency with the Hawking-Page phase transition. Namely, the dominance of the black hole configurational entropy will be shown to increase with the temperature. In order to verify the consistency of the new procedure developed here, we also consider the case of black holes in flat space-time. For such a black hole, it is known that evaporation leads to instability. The configurational entropy obtained for the flat space case is thoroughly consistent with the physical expectation. In fact, we show that the smaller the black holes, the more unstable they are. So, the configurational entropy furnishes a reliable measure for stability of black holes.

  5. Configurational entropy of anti-de Sitter black holes

    Directory of Open Access Journals (Sweden)

    Nelson R.F. Braga

    2017-04-01

    Full Text Available Recent studies indicate that the configurational entropy is an useful tool to investigate the stability and (or the relative dominance of states for diverse physical systems. Recent examples comprise the connection between the variation of this quantity and the relative fraction of light mesons and glueballs observed in hadronic processes. Here we develop a technique for defining a configurational entropy for an AdS-Schwarzschild black hole. The achieved result corroborates consistency with the Hawking–Page phase transition. Namely, the dominance of the black hole configurational entropy will be shown to increase with the temperature. In order to verify the consistency of the new procedure developed here, we also consider the case of black holes in flat space-time. For such a black hole, it is known that evaporation leads to instability. The configurational entropy obtained for the flat space case is thoroughly consistent with the physical expectation. In fact, we show that the smaller the black holes, the more unstable they are. So, the configurational entropy furnishes a reliable measure for stability of black holes.

  6. Configurational entropy of anti-de Sitter black holes

    International Nuclear Information System (INIS)

    Braga, Nelson R.F.; Rocha, Roldão da

    2017-01-01

    Recent studies indicate that the configurational entropy is an useful tool to investigate the stability and (or) the relative dominance of states for diverse physical systems. Recent examples comprise the connection between the variation of this quantity and the relative fraction of light mesons and glueballs observed in hadronic processes. Here we develop a technique for defining a configurational entropy for an AdS-Schwarzschild black hole. The achieved result corroborates consistency with the Hawking–Page phase transition. Namely, the dominance of the black hole configurational entropy will be shown to increase with the temperature. In order to verify the consistency of the new procedure developed here, we also consider the case of black holes in flat space-time. For such a black hole, it is known that evaporation leads to instability. The configurational entropy obtained for the flat space case is thoroughly consistent with the physical expectation. In fact, we show that the smaller the black holes, the more unstable they are. So, the configurational entropy furnishes a reliable measure for stability of black holes.

  7. BRST quantization in anti-de Sitter space

    CERN Document Server

    Kallosh, Renata E

    2000-01-01

    We discuss the status of the superstring theory on ad S/sub 5/*S/sup 5/ space and difficulties with its quantization due to the nonlinear realization of the SU(2,2 4) superconformal symmetry. We propose a toy model in two dimensions where this symmetry is realized linearly and supertwistors are used as `quarks' of this supergroup. A possible relation between the string theory and the toy model is studied in the case of a massive particle propagating in AdS/sub 5/ space: a generalized twistor construction is shown to lead to a quadratic action and simple BRST quantization. We hope that these results will help to also eventually quantize the string on ad S/sub 5/*S/sup 5/. (10 refs).

  8. Configurational entropy of anti-de Sitter black holes

    Energy Technology Data Exchange (ETDEWEB)

    Braga, Nelson R.F., E-mail: braga@if.ufrj.br [Instituto de Física, Universidade Federal do Rio de Janeiro, Caixa Postal 68528, RJ 21941-972 (Brazil); Rocha, Roldão da, E-mail: roldao.rocha@ufabc.edu.br [Centro de Matemática, Computação e Cognição, Universidade Federal do ABC – UFABC, 09210-580, Santo André (Brazil)

    2017-04-10

    Recent studies indicate that the configurational entropy is an useful tool to investigate the stability and (or) the relative dominance of states for diverse physical systems. Recent examples comprise the connection between the variation of this quantity and the relative fraction of light mesons and glueballs observed in hadronic processes. Here we develop a technique for defining a configurational entropy for an AdS-Schwarzschild black hole. The achieved result corroborates consistency with the Hawking–Page phase transition. Namely, the dominance of the black hole configurational entropy will be shown to increase with the temperature. In order to verify the consistency of the new procedure developed here, we also consider the case of black holes in flat space-time. For such a black hole, it is known that evaporation leads to instability. The configurational entropy obtained for the flat space case is thoroughly consistent with the physical expectation. In fact, we show that the smaller the black holes, the more unstable they are. So, the configurational entropy furnishes a reliable measure for stability of black holes.

  9. Newton-Hooke Limit of Beltrami-de Sitter Spacetime, Principles of Galilei-Hooke's Relativity and Postulate on Newton-Hooke Universal Time

    OpenAIRE

    Huang, Chao-Guang; Guo, Han-Ying; Tian, Yu; Xu, Zhan; Zhou, Bin

    2004-01-01

    Based on the Beltrami-de Sitter spacetime, we present the Newton-Hooke model under the Newton-Hooke contraction of the $BdS$ spacetime with respect to the transformation group, algebra and geometry. It is shown that in Newton-Hooke space-time, there are inertial-type coordinate systems and inertial-type observers, which move along straight lines with uniform velocity. And they are invariant under the Newton-Hooke group. In order to determine uniquely the Newton-Hooke limit, we propose the Gal...

  10. Schwarzschild-de Sitter spacetime: The role of temperature in the emission of Hawking radiation

    Science.gov (United States)

    Pappas, Thomas; Kanti, Panagiota

    2017-12-01

    We consider a Schwarzschild-de Sitter (SdS) black hole, and focus on the emission of massless scalar fields either minimally or non-minimally coupled to gravity. We use six different temperatures, two black-hole and four effective ones for the SdS spacetime, as the question of the proper temperature for such a background is still debated in the literature. We study their profiles under the variation of the cosmological constant, and derive the corresponding Hawking radiation spectra. We demonstrate that only few of these temperatures may support significant emission of radiation. We finally compute the total emissivities for each temperature, and show that the non-minimal coupling constant of the scalar field to gravity also affects the relative magnitudes of the energy emission rates.

  11. Effect of a magnetic field on Schwinger mechanism in de Sitter spacetime

    Science.gov (United States)

    Bavarsad, Ehsan; Kim, Sang Pyo; Stahl, Clément; Xue, She-Sheng

    2018-01-01

    We investigate the effect of a uniform magnetic field background on scalar QED pair production in a four-dimensional de Sitter spacetime (dS4 ). We obtain a pair production rate which agrees with the known Schwinger result in the limit of Minkowski spacetime and with Hawking radiation in dS spacetime in the zero electric field limit. Our results describe how the cosmic magnetic field affects the pair production rate in cosmological setups. In addition, using the zeta function regularization scheme we calculate the induced current and examine the effect of a magnetic field on the vacuum expectation value of the current operator. We find that, in the case of a strong electromagnetic background the current responds as E .B , while in the infrared regime, it responds as B /E , which leads to a phenomenon of infrared hyperconductivity. These results for the induced current have important applications for the cosmic magnetic field evolution.

  12. Scalar potential from de Sitter brane in 5D and effective cosmological constant

    International Nuclear Information System (INIS)

    Ito, Masato

    2004-01-01

    We derive the scalar potential in zero mode effective action arising from a de Sitter brane embedded in five dimensions with bulk cosmological constant Λ. The scalar potential for a scalar field canonically normalized is given by the sum of exponential potentials. In the case of Λ = 0 and Λ > 0, we point out that the scalar potential has an unstable maximum at the origin and exponentially vanishes for large positive scalar field. In the case of Λ < 0, the scalar potential has an unstable maximum at the origin and a local minimum. It is shown that the positive cosmological constant in dS brane is reduced by negative potential energy of scalar at minimum and that effective cosmological constant depends on a dimensionless quantity. Furthermore, we discuss the fate of our universe including the potential energy of the scalar. (author)

  13. Nonsingular black holes, wormholes, and de Sitter cores from anisotropic fluids

    Science.gov (United States)

    Menchon, Cintia C.; Olmo, Gonzalo J.; Rubiera-Garcia, Diego

    2017-11-01

    We study Born-Infeld gravity coupled to an anisotropic fluid in a static, spherically symmetric background. The free function characterizing the fluid is selected on the following grounds: i) recovery of the Reissner-Nordström solution of General Relativity at large distances, ii) fulfillment of classical energy conditions, and iii) inclusion of models of nonlinear electrodynamics as particular examples. Four branches of solutions are obtained, depending on the signs of two parameters on the gravity and matter sectors. On each branch, we discuss in detail the modifications on the innermost region of the corresponding solutions, which provides a plethora of configurations, including nonsingular black holes and naked objects, wormholes, and de Sitter cores. The regular character of these configurations is discussed according to the completeness of geodesics and the behavior of curvature scalars.

  14. Reply to "Comment on `Fermion production in a magnetic field in a de Sitter universe"'

    Science.gov (United States)

    Crucean, Cosmin; Bǎloi, Mihaela-Andreea

    2017-02-01

    In this paper, we study the problem of gauge invariance of the first order transition amplitudes in de Sitter QED in the Coulomb gauge. We consider the gauge transformations which preserve the Coulomb gauge, that contain the gradient of the gauge function. The final results prove that the first order transition amplitudes do not change at a gradient transformation of the vector potential because the only allowed transformation is Λ =0 . Our results suggest that the remarks made in the comment by Nicolaevici and Farkas [this issue, Phys. Rev. D 95, 048501 (2017), 10.1103/PhysRevD.95.048501] are not directly applicable to the results in our paper since their proposed gauge transformations do not preserve the Coulomb gauge.

  15. Quantum radiation of Maxwell’s electromagnetic field in nonstationary Kerr-de Sitter black hole

    Science.gov (United States)

    Ibungochouba Singh, T.; Ablu Meitei, I.; Yugindro Singh, K.

    2016-03-01

    Quantum radiation properties of nonstationary Kerr-de Sitter (KdS) black hole is investigated using the method of generalized tortoise coordinate transformation. The locations of horizons and the temperature of the thermal radiation as well as the maximum energy of the nonthermal radiation are derived. It is found that the surface gravity and the Hawking temperature depend on both time and different angles. An extra coupling effect is obtained in the thermal radiation spectrum of Maxwell’s electromagnetic field equations which is absent in the thermal radiation spectrum of scalar particles. Further, the chemical potential derived from the thermal radiation spectrum of scalar particle has been found to be equal to the highest energy of the negative energy state of the scalar particle in the nonthermal radiation for KdS black hole. It is also shown that the generalized tortoise coordinate transformation produces a constant term in the expression of the surface gravity and Hawking temperature.

  16. Non-minimal Particle Creation from Asymptotic-de Sitter Inflation

    Science.gov (United States)

    Yusofi, E.; Mohsenzadeh, M.

    2018-03-01

    A general form of quasi-de Sitter(dS) modes is used to study the creation of particle during the inflation. Actually, by considering the general form of inflaton field equation as a function of the Hankel function index and by using the Planck 2015 constraint on spectral index, we obtain the possible new constraints for the values of coupling constant in the era with asymptotic-dS space-time. Then, we explicitly calculate the general form of expectation value of the created particles in terms of the Hankel function index and the conformal time. The correction terms in the number of created particles are very tiny in the early time but can have the significant effects in the later universe. Our result is general and at the early time limit confirm the conventional special results for the Minkowski and dS background.

  17. De Sitter and scaling solutions in a higher-order modified teleparallel theory

    Energy Technology Data Exchange (ETDEWEB)

    Paliathanasis, Andronikos, E-mail: anpaliat@phys.uoa.gr [Instituto de Ciencias Físicas y Matemáticas, Universidad Austral de Chile, Valdivia (Chile)

    2017-08-01

    The existence and the stability conditions for some exact relativistic solutions of special interest are studied in a higher-order modified teleparallel gravitational theory. The theory with the use of a Lagrange multiplier is equivalent with that of General Relativity with a minimally coupled noncanonical field. The conditions for the existence of de Sitter solutions and ideal gas solutions in the case of vacuum are studied as also the stability criteria. Furthermore, in the presence of matter the behaviour of scaling solutions is given. Finally, we discuss the degrees of freedom of the field equations and we reduce the field equations in an algebraic equation, where in order to demonstrate our result we show how this noncanonical scalar field can reproduce the Hubble function of Λ-cosmology.

  18. De Sitter vacua and inflation in no-scale string models

    International Nuclear Information System (INIS)

    Gross, Christian

    2009-09-01

    This thesis studies the question of how de Sitter vacua and slow-roll inflation may be realized in string-motivated models. More specifically, we consider 4d N = 1 supergravity theories (without vector multiplets) with Kaehler potentials which are 'no-scale' at leading order. Such theories frequently arise in the moduli sector of string compactifications. We discuss a condition on the scalar geometry (defined by the Kaehler potential) and on the direction of supersymmetry breaking in the scalar manifold, which has to be met in order for the average of the masses of the sGoldstinos to be positive, and hence for metastable vacua to be possible. This condition also turns out to be necessary for the existence of trajectories admitting slow-roll inflation. Its implications for certain scalar manifolds which arise from Calabi-Yau string compactifications are discussed. In particular, for two-moduli models arising from compactifications of heterotic- and type IIB string theory, a simple criterion on the intersection numbers needs to be satisfied for possible de Sitter phases to exist. In addition, we show that subleading corrections breaking the no-scale property may allow the condition on the scalar geometry to be fulfilled, even when it is violated at leading order. Finally, we develop a procedure to construct superpotentials for a given viable Kaehler potential, such that the scalar potential has a realistic local minimum. We propose two-moduli models, with superpotentials which could arise from flux backgrounds and non-perturbative effects, which have a viable vacuum without employing subleading corrections or an uplifting sector. (orig.)

  19. De Sitter vacua and inflation in no-scale string models

    Energy Technology Data Exchange (ETDEWEB)

    Gross, Christian

    2009-09-15

    This thesis studies the question of how de Sitter vacua and slow-roll inflation may be realized in string-motivated models. More specifically, we consider 4d N = 1 supergravity theories (without vector multiplets) with Kaehler potentials which are 'no-scale' at leading order. Such theories frequently arise in the moduli sector of string compactifications. We discuss a condition on the scalar geometry (defined by the Kaehler potential) and on the direction of supersymmetry breaking in the scalar manifold, which has to be met in order for the average of the masses of the sGoldstinos to be positive, and hence for metastable vacua to be possible. This condition also turns out to be necessary for the existence of trajectories admitting slow-roll inflation. Its implications for certain scalar manifolds which arise from Calabi-Yau string compactifications are discussed. In particular, for two-moduli models arising from compactifications of heterotic- and type IIB string theory, a simple criterion on the intersection numbers needs to be satisfied for possible de Sitter phases to exist. In addition, we show that subleading corrections breaking the no-scale property may allow the condition on the scalar geometry to be fulfilled, even when it is violated at leading order. Finally, we develop a procedure to construct superpotentials for a given viable Kaehler potential, such that the scalar potential has a realistic local minimum. We propose two-moduli models, with superpotentials which could arise from flux backgrounds and non-perturbative effects, which have a viable vacuum without employing subleading corrections or an uplifting sector. (orig.)

  20. Dispersion Relations for Isothermal Plasma around the Horizon of Reissner–Nordström–de Sitter Black Hole

    International Nuclear Information System (INIS)

    Hasan, M. Khayrul; Ali, M. Hossain

    2009-01-01

    We formulate the general relativistic magnetohydrodynamic equations for isothermal plasma in spatially flat Reissner–Nordström–de Sitter metric by using 3+1 split of spacetime. Respective perturbed equations are linearized for rotating magnetized surroundings. These are then Fourier analyzed and the corresponding dispersion relations are obtained. These relations are discussed both analytically and numerically in order to investigate the nature of waves with positive angular frequency around the horizon

  1. Quantum field theory in curved space-times: with an application to the reduced model of deSitter universe

    International Nuclear Information System (INIS)

    Peter, I. J.

    1995-06-01

    The work deals with space-times with fixed background metric. The topics were arranged in a straight course, the first chapter collects basic facts on Lorentzian manifolds as time-orientability, causal structure, ... Further free neutral scalar fields and spinor fields described by the Klein-Gordon equation resp. the Dirac equation are dealt with. Having in mind the construction of the Weyl algebra and the Fermi algebra in the second chapter, it was put emphasis on the structure of the spaces of solutions of these equations: In the first case the space of solutions is a symplectic vector space in a canonical manner, in the second case a Hilbert space. It was made some effort to stay as general as possible. Most of the material in the second chapter already exists for several years, but it is largely scattered over various journal articles. In the third chapter the construction of a vacuum on the special example of deSitter universe is described. A close investigation of a recent work by J. Bros and U. Moschella made it possible to refine a result concerning temperature felt by an accelerated observer in deSitter space. The last part of this thesis is concerned with vacua for spinor fields on the two-dimensional deSitter universe. A procedure introduced by R. Haag, H. Narnhofer and U. Stein for four dimensional space-times does not seem to work in two dimensions. (author)

  2. Tunneling probability for the birth of an asymptotically de Sitter universe

    International Nuclear Information System (INIS)

    Acacio de Barros, J.; Correa Silva, E. V.; Monerat, G. A.; Oliveira-Neto, G.; Ferreira Filho, L. G.; Romildo, P. Jr.

    2007-01-01

    In the present work, we quantize a closed Friedmann-Robertson-Walker model in the presence of a positive cosmological constant and radiation. It gives rise to a Wheeler-DeWitt equation for the scale factor which has the form of a Schroedinger equation for a potential with a barrier. We solve it numerically and determine the tunneling probability for the birth of a asymptotically DeSitter, inflationary universe, initially, as a function of the mean energy of the initial wave function. Then, we verify that the tunneling probability increases with the cosmological constant, for a fixed value of the mean energy of the initial wave function. Our treatment of the problem is more general than previous ones, based on the WKB approximation. That is the case because we take into account the fact that the scale factor (a) cannot be smaller than zero. It means that, one has to introduce an infinity potential wall at a=0, which forces any wave packet to be zero there. That condition introduces new results, in comparison with previous works

  3. Stability, tunneling and flux changing de Sitter transitions in the large volume string scenario

    Science.gov (United States)

    de Alwis, S.; Gupta, R.; Hatefi, E.; Quevedo, F.

    2013-11-01

    We study the non-perturbative stability of the Large Volume Scenario (LVS) of IIB string compactifications, by analysing transitions mediated by the Brown-Teitelboim (BT) brane nucleations and by Coleman De Luccia tunneling (CDL). We find that, as long as the effective field theory description holds, the LVS AdS minima are stable despite being non-supersymmetric. This opens the possibility of having a CFT dual. Metastable de Sitter vacua behave differently depending on the uplifting mechanism. We find explicit expressions for the different decay rates in terms of exponentials of the volume. Among the transitions of dS to dS those with increasing volume and decreasing vacuum energy are preferred, though dS decays to AdS (big-crunch sinks) have higher probability. Transitions via the CDL mechanism to decompactification are exponentially suppressed compared to these. The BT decays correspond to flux/D3 brane transitions mediated by the nucleation of D5/NS5 branes. We compare our results with previous analysis for KKLT, type IIA, and 6D Einstein-Maxwell studies. In particular we find no indication for a bubble of nothing decay.

  4. Localization of gauge fields in a tachyonic de Sitter thick braneworld

    Energy Technology Data Exchange (ETDEWEB)

    Herrera-Aguilar, Alfredo [Universidad Autonoma de Chiapas, Ciudad Universitaria, Mesoamerican Centre for Theoretical Physics, Kilometro 4, Carretera Emiliano Zapata, Colonia Real del Bosque (Teran), Tuxtla Gutierrez, Chiapas (Mexico); Universidad Autonoma Metropolitana Iztapalapa, Departamento de Fisica, Mexico, D.F. (Mexico); Universidad Michoacana de San Nicolas de Hidalgo, Instituto de Fisica y Matematicas, Morelia, Michoacan (Mexico); Rojas, Alma D. [Universidad Autonoma de Chiapas, Ciudad Universitaria, Mesoamerican Centre for Theoretical Physics, Kilometro 4, Carretera Emiliano Zapata, Colonia Real del Bosque (Teran), Tuxtla Gutierrez, Chiapas (Mexico); AHEP Group, Instituto de Fisica Corpuscular C.S.I.C./Universitat de Valencia, Paterna (Valencia) (Spain); Santos, Eli [Universidad Autonoma de Chiapas, Ciudad Universitaria, Mesoamerican Centre for Theoretical Physics, Kilometro 4, Carretera Emiliano Zapata, Colonia Real del Bosque (Teran), Tuxtla Gutierrez, Chiapas (Mexico)

    2014-04-15

    In this work we show that universal gauge vector fields can be localized on the recently proposed 5D thick tachyonic braneworld which involves a de Sitter cosmological background induced on the 3-brane. Namely, by performing a suitable decomposition of the vector field, the resulting 4D effective action corresponds to a massive gauge field, while the profile along the extra dimension obeys a Schroedinger-like equation with a Poeschl-Teller potential. It turns out that the massless zero mode of the gauge field is bound to the expanding 3-brane and allows us to recover the standard 4D electromagnetic phenomena of our world. Moreover, this zero mode is separated from the continuum of Kaluza-Klein (KK) modes by a mass gap determined by the scale of the expansion parameter. We also were able to analytically solve the corresponding Schroedinger-like equation for arbitrary mass, showing that KK massive modes asymptotically behave like plane waves, as expected. (orig.)

  5. Quadratic curvature terms and deformed Schwarzschild–de Sitter black hole analogues in the laboratory

    Directory of Open Access Journals (Sweden)

    R. da Rocha

    2017-12-01

    Full Text Available Sound waves on a fluid stream, in a de Laval nozzle, are shown to correspond to quasinormal modes emitted by black holes that are physical solutions in a quadratic curvature gravity with cosmological constant. Sound waves patterns in transsonic regimes at a laboratory are employed here to provide experimental data regarding generalized theories of gravity, comprised by the exact de Sitter-like solution and a perturbative solution around the Schwarzschild–de Sitter standard solution as well. Using the classical tests of General Relativity to bound free parameters in these solutions, acoustic perturbations on fluid flows in nozzles are then regarded, to study quasinormal modes of these black holes solutions, providing deviations of the de Laval nozzle cross-sectional area, when compared to the Schwarzschild solution. The fluid sonic point in the nozzle, for sound waves in the fluid, is shown to implement the acoustic event horizon corresponding to quasinormal modes. Keywords: Black holes, Fluid branes, Fluid dynamics, Quadratic curvature gravity, de Laval nozzle

  6. Evidence for Galaxy Dynamics Tracing Background Cosmology Below the de Sitter Scale of Acceleration

    Science.gov (United States)

    Van Putten, Maurice H.

    2018-01-01

    Galaxy dynamics probes weak gravity at accelerations below the de Sitter scale of acceleration $a_{dS}=cH$, where $c$ is the velocity of light and $H$ is the Hubble parameter. Low and high redshift galaxies hereby offer a novel probe of weak gravity in an evolving cosmology, satisfying $H(z)=H_0\\sqrt{1+\\omega_m(6z+12z^2+12z^3+6z^4+(6/5)z^5)}/(1+z)$ with baryonic matter content $\\omega_m=0.2808\\pm0.028$ sans tension to $H_0$ in surveys of the Local Universe. Galaxy rotation curves show anomalous galaxy dynamics in weak gravity $a_Ninertia from entanglement entropy, that introduces a $C^0$ onset across $a_N=a_{dS}$ with asymptotic behavior described by a Milgrom parameter satisfying $a_0=\\omega_0/2\\pi$, where $\\omega_0=\\sqrt{1-q}H$ is a fundamental eigenfrequency of the cosmological horizon. Extending an earlier confrontation with data covering $0.003\\lesssim a_N/a_{dS}\\lesssim1$ at redshift $z\\sim0$ in Lellie et al. (2016), the modest anomalous behavior in the Genzel et al. sample at redshifts $0.854\\le z\\le 2.282$ is found to be mostly due to clustering $0.36\\lesssim a_N/a_{dS}\\lesssim1$ close to the $C^0$ onset to weak gravity and an increase of up to 65\\% in $a_0$.

  7. Bulk and brane decay of a (4+n)-dimensional Schwarzschild-de Sitter black hole: Scalar radiation

    International Nuclear Information System (INIS)

    Kanti, P.; Grain, J.; Barrau, A.

    2005-01-01

    In this paper, we extend the idea that the spectrum of Hawking radiation can reveal valuable information on a number of parameters that characterize a particular black hole background--such as the dimensionality of spacetime and the value of coupling constants--to gain information on another important aspect: the curvature of spacetime. We investigate the emission of Hawking radiation from a D-dimensional Schwarzschild-de Sitter black hole emitted in the form of scalar fields, and employ both analytical and numerical techniques to calculate greybody factors and differential energy emission rates on the brane and in the bulk. The energy emission rate of the black hole is significantly enhanced in the high-energy regime with the number of spacelike dimensions. On the other hand, in the low-energy part of the spectrum, it is the cosmological constant that leaves a clear footprint, through a characteristic, constant emission rate of ultrasoft quanta determined by the values of black hole and cosmological horizons. Our results are applicable to 'small' black holes arising in theories with an arbitrary number and size of extra dimensions, as well as to pure 4-dimensional primordial black holes, embedded in a de Sitter spacetime

  8. Coulomb’s law corrections and fermion field localization in a tachyonic de Sitter thick braneworld

    Energy Technology Data Exchange (ETDEWEB)

    Cartas-Fuentevilla, Roberto; Escalante, Alberto [Instituto de Física, Benemérita Universidad Autónoma de Puebla,Apdo. postal J-48, 72570 Puebla, Pue. (Mexico); Germán, Gabriel [Instituto de Ciencias Físicas, Universidad Nacional Autónoma de México,Apdo. Postal 48-3, 62251 Cuernavaca, Morelos (Mexico); Rudolf Peierls Centre for Theoretical Physics, University of Oxford, 1 Keble Road,Oxford, OX1 3NP (United Kingdom); Herrera-Aguilar, Alfredo [Instituto de Física, Benemérita Universidad Autónoma de Puebla,Apdo. postal J-48, 72570 Puebla, Pue. (Mexico); Institutode Física y Matemáticas, Universidad Michoacana de San Nicolás de Hidalgo,Edificio C-3, Ciudad Universitaria, CP 58040, Morelia, Michoacán (Mexico); Mora-Luna, Refugio Rigel [Instituto de Ciencias Físicas, Universidad Nacional Autónoma de México,Apdo. Postal 48-3, 62251 Cuernavaca, Morelos (Mexico)

    2016-05-11

    Following recent studies which show that it is possible to localize gravity as well as scalar and gauge vector fields in a tachyonic de Sitter thick braneworld, we investigate the solution of the gauge hierarchy problem, the localization of fermion fields in this model, the recovering of the Coulomb law on the non-relativistic limit of the Yukawa interaction between bulk fermions and gauge bosons localized in the brane, and confront the predicted 5D corrections to the photon mass with its upper experimental/observational bounds, finding the model physically viable since it passes these tests. In order to achieve the latter aims we first consider the Yukawa interaction term between the fermionic and the tachyonic scalar fields MF(T)ΨΨ-bar in the action and analyze four distinct tachyonic functions F(T) that lead to four different structures of the respective fermionic mass spectra with different physics. In particular, localization of the massless left-chiral fermion zero mode is possible for three of these cases. We further analyze the phenomenology of these Yukawa interactions among fermion fields and gauge bosons localized on the brane and obtain the crucial and necessary information to compute the corrections to Coulomb’s law coming from massive KK vector modes in the non-relativistic limit. These corrections are exponentially suppressed due to the presence of the mass gap in the mass spectrum of the bulk gauge vector field. From our results we conclude that corrections to Coulomb’s law in the thin brane limit have the same form (up to a numerical factor) as far as the left-chiral massless fermion field is localized on the brane. Finally we compute the corrections to the Coulomb’s law for an arbitrarily thick brane scenario which can be interpreted as 5D corrections to the photon mass. By performing consistent estimations with brane phenomenology, we found that the predicted corrections to the photon mass, which are well bounded by the experimentally

  9. Einstein's cosmology review of 1933: a new perspective on the Einstein-de Sitter model of the cosmos

    Science.gov (United States)

    O'Raifeartaigh, Cormac; O'Keeffe, Michael; Nahm, Werner; Mitton, Simon

    2015-09-01

    We present a first English translation and analysis of a little-known review of relativistic cosmology written by Albert Einstein in late 1932. The article, which was published in 1933 in a book of Einstein papers translated into French, contains a substantial review of static and dynamic relativistic models of the cosmos, culminating in a discussion of the Einstein-de Sitter model. The article offers a valuable contemporaneous insight into Einstein's cosmology in the early 1930s and confirms that his interest lay in the development of the simplest model of the cosmos that could account for observation. The article also confirms that Einstein did not believe that simplified relativistic models could give an accurate description of the early universe.

  10. Schwarzschild–de Sitter spacetime: The role of temperature in the emission of Hawking radiation

    Directory of Open Access Journals (Sweden)

    Thomas Pappas

    2017-12-01

    Full Text Available We consider a Schwarzschild–de Sitter (SdS black hole, and focus on the emission of massless scalar fields either minimally or non-minimally coupled to gravity. We use six different temperatures, two black-hole and four effective ones for the SdS spacetime, as the question of the proper temperature for such a background is still debated in the literature. We study their profiles under the variation of the cosmological constant, and derive the corresponding Hawking radiation spectra. We demonstrate that only few of these temperatures may support significant emission of radiation. We finally compute the total emissivities for each temperature, and show that the non-minimal coupling constant of the scalar field to gravity also affects the relative magnitudes of the energy emission rates.

  11. 2 + 1 dimensional de Sitter universe emerging from the gauge structure of a nonlinear quantum system.

    Science.gov (United States)

    Kam, Chon-Fai; Liu, Ren-Bao

    2017-08-29

    Berry phases and gauge structures are fundamental quantum phenomena. In linear quantum mechanics the gauge field in parameter space presents monopole singularities where the energy levels become degenerate. In nonlinear quantum mechanics, which is an effective theory of interacting quantum systems, there can be phase transitions and hence critical surfaces in the parameter space. We find that these critical surfaces result in a new type of gauge field singularity, namely, a conic singularity that resembles the big bang of a 2 + 1 dimensional de Sitter universe, with the fundamental frequency of Bogoliubov excitations acting as the cosmic scale, and mode softening at the critical surface, where the fundamental frequency vanishes, causing a causal singularity. Such conic singularity may be observed in various systems such as Bose-Einstein condensates and molecular magnets. This finding offers a new approach to quantum simulation of fundamental physics.

  12. A new laser-ranged satellite for General Relativity and space geodesy: III. De Sitter effect and the LARES 2 space experiment

    Science.gov (United States)

    Ciufolini, Ignazio; Matzner, Richard; Gurzadyan, Vahe; Penrose, Roger

    2017-12-01

    In two previous papers we presented the LARES 2 space experiment aimed at a very accurate test of frame-dragging and at other tests of fundamental physics and measurements of space geodesy and geodynamics. We presented the error sources of the LARES 2 experiment, its error budget and Monte Carlo simulations and covariance analyses confirming an accuracy of a few parts in one thousand in the test of frame-dragging. Here we discuss the impact of the orbital perturbation known as the de Sitter effect, or geodetic precession, in the error budget of the LARES 2 frame-dragging experiment. We show that the uncertainty in the de Sitter effect has a negligible impact in the final error budget because of the very accurate results now available for the test of the de Sitter precession and because of its very nature. The total error budget in the LARES 2 test of frame-dragging remains at a level of the order of 0.2%, as determined in the first two papers of this series.

  13. A new laser-ranged satellite for General Relativity and space geodesy. III. De Sitter effect and the LARES 2 space experiment

    Energy Technology Data Exchange (ETDEWEB)

    Ciufolini, Ignazio [Universita del Salento, Dipt. Ingegneria dell' Innovazione, Lecce (Italy); Centro Fermi, Rome (Italy); Matzner, Richard [University of Texas, Theory Group, Austin (United States); Gurzadyan, Vahe [Alikhanian National Laboratory and Yerevan State University, Center for Cosmology and Astrophysics, Yerevan (Armenia); Penrose, Roger [University of Oxford, Mathematical Institute, Oxford (United Kingdom)

    2017-12-15

    In two previous papers we presented the LARES 2 space experiment aimed at a very accurate test of frame-dragging and at other tests of fundamental physics and measurements of space geodesy and geodynamics. We presented the error sources of the LARES 2 experiment, its error budget and Monte Carlo simulations and covariance analyses confirming an accuracy of a few parts in one thousand in the test of frame-dragging. Here we discuss the impact of the orbital perturbation known as the de Sitter effect, or geodetic precession, in the error budget of the LARES 2 frame-dragging experiment. We show that the uncertainty in the de Sitter effect has a negligible impact in the final error budget because of the very accurate results now available for the test of the de Sitter precession and because of its very nature. The total error budget in the LARES 2 test of frame-dragging remains at a level of the order of 0.2%, as determined in the first two papers of this series. (orig.)

  14. Inside anti-wind groups

    International Nuclear Information System (INIS)

    Rap, C.

    2010-01-01

    At the beginning the opposition to wind turbines was based on the preservation of the landscape. Now as wind farms are more frequent, the reasons to fight them become more concrete: -) the loss of value of properties due to the installation of a wind turbine in the surroundings, -) the noise and the view, or -) the impact on the fauna. More and more people question the choice of wind power as an efficient and reliable source of energy. In France about a few tens of thousand people are registered in associations of opponents to wind energy. These associations have merged into 2 main federations: 'Vent de colere' and 'Federation Environement Durable'. In october 2008 Apaw, a European platform against wind energy, was founded. Apaw gathers 400 federations from 21 European countries. Wind energy opponents are getting momentum, they are becoming experts on how to communicate, how to organize demonstrations, how to take legal actions and on active lobbying. (A.C.)

  15. The Effect of de-Sitter Like Background on Increasing the Zero Point Budget of Dark Energy

    International Nuclear Information System (INIS)

    Aghamohammadi, Ali; Saaidi, Khaled; Sheikhahmadi, Haidar

    2016-01-01

    During this work, using subtraction renormalization mechanism, zero point quantum fluctuations for bosonic scalar fields in a de-Sitter like background are investigated. By virtue of the observed value for spectral index, n s (k), for massive scalar field the best value for the first slow roll parameter, ϵ, is achieved. In addition, the energy density of vacuum quantum fluctuations for massless scalar field is obtained. The effects of these fluctuations on other components of the universe are studied. By solving the conservation equation, for some different examples, the energy density for different components of the universe is obtained. In the case which all components of the universe are in an interaction, the different dissipation functions, Q-tilde i , are considered. The time evolution of ρ DE (z)/ρ cri (z) shows that Q-tilde=3γH(t)ρ m has the best agreement in comparison to observational data including CMB, BAO, and SNeIa data set.

  16. Stability of the Schwarzschild–de Sitter black hole in the dRGT massive gravity theory

    International Nuclear Information System (INIS)

    Kodama, Hideo; Arraut, Ivan

    2014-01-01

    The Schwarzschild–de Sitter solution in the Einstein theory with a positive cosmological constant Λ=m 2 /α becomes an exact solution to the de Rham–Gabadadze–Tolley (dRGT) nonlinear massive gravity theory with the mass parameter m when the theory parameters α and β satisfy the relation β=α 2 . We study the perturbative behavior of this black hole solution in the nonlinear dRGT theory with β=α 2 . We find that the linear perturbation equations become identical to those for the vacuum Einstein theory when they are expressed in terms of gauge-invariant variables. This implies that this black hole is stable in the dRGT theory as far as the spacetime structure is concerned, in contrast to the case of the bi-Schwarzschild solution in the bi-metric theory. However, we have also found a pathological feature that the general solution to the perturbation equations contain a single arbitrary function of spacetime coordinates. This implies a degeneracy of dynamics in the Stückelberg field sector at the linear perturbation level in this background. The physical significance of this degeneracy depends on how the Stückelberg fields couple observable fields

  17. Quantum groups and noncommutative spacetimes with cosmological constant

    Science.gov (United States)

    Ballesteros, A.; Gutiérrez-Sagredo, I.; Herranz, F. J.; Meusburger, C.; Naranjo, P.

    2017-08-01

    Noncommutative spacetimes are widely believed to model some properties of the quantum structure of spacetime at the Planck regime. In this contribution the construction of (anti-)de Sitter noncommutative spacetimes obtained through quantum groups is reviewed. In this approach the quantum deformation parameter z is related to a Planck scale, and the cosmological constant plays the role of a second deformation parameter of geometric nature, whose limit Λ → 0 provides the corresponding noncommutative Minkowski spacetimes.

  18. Direct and inverse scattering at fixed energy for massless charged Dirac fields by Kerr-Newman-de Sitter black holes

    CERN Document Server

    Daudé, Thierry

    2017-01-01

    In this paper, the authors study the direct and inverse scattering theory at fixed energy for massless charged Dirac fields evolving in the exterior region of a Kerr-Newman-de Sitter black hole. In the first part, they establish the existence and asymptotic completeness of time-dependent wave operators associated to our Dirac fields. This leads to the definition of the time-dependent scattering operator that encodes the far-field behavior (with respect to a stationary observer) in the asymptotic regions of the black hole: the event and cosmological horizons. The authors also use the miraculous property (quoting Chandrasekhar)-that the Dirac equation can be separated into radial and angular ordinary differential equations-to make the link between the time-dependent scattering operator and its stationary counterpart. This leads to a nice expression of the scattering matrix at fixed energy in terms of stationary solutions of the system of separated equations. In a second part, the authors use this expression of ...

  19. Holography in three-dimensional Kerr-de Sitter space with a gravitational Chern-Simons term

    International Nuclear Information System (INIS)

    Park, Mu-In

    2008-01-01

    The holographic description of the three-dimensional Kerr-de Sitter space with a gravitational Chern-Simons term is studied, in the context of dS/CFT correspondence. The space has only one (cosmological) event horizon and its mass and angular momentum are identified from the holographic energy-momentum tensor at the asymptotic infinity. The thermodynamic entropy of the cosmological horizon is computed directly from the first law of thermodynamics, with the conventional Hawking temperature, and it is found that the usual Gibbons-Hawking entropy is modified. It is remarked that, due to the gravitational Chern-Simons term, (a) the results go beyond the analytic continuation from AdS, (b) the maximum-mass/N-bound conjecture may be violated and (c) the three-dimensional cosmology is chiral. A statistical mechanical computation of the entropy, from a Cardy-like formula for a dual CFT at the asymptotic boundary, is discussed. Some remarks on the technical differences in the Chern-Simons energy-momentum tensor, from the literature, are also made

  20. Examining a covariant and renormalizable quantum field theory in de Sitter space by studying “black hole radiation”

    Science.gov (United States)

    Pejhan, Hamed; Rahbardehghan, Surena

    2016-04-01

    Respecting that any consistent quantum field theory in curved space-time must include black hole radiation, in this paper, we examine the Krein-Gupta-Bleuler (KGB) formalism as an inevitable quantization scheme in order to follow the guideline of the covariance of minimally coupled massless scalar field and linear gravity on de Sitter (dS) background in the sense of Wightman-Gärding approach, by investigating thermodynamical aspects of black holes. The formalism is interestingly free of pathological large distance behavior. In this construction, also, no infinite term appears in the calculation of expectation values of the energy-momentum tensor (we have an automatic and covariant renormalization) which results in the vacuum energy of the free field to vanish. However, the existence of an effective potential barrier, intrinsically created by black holes gravitational field, gives a Casimir-type contribution to the vacuum expectation value of the energy-momentum tensor. On this basis, by evaluating the Casimir energy-momentum tensor for a conformally coupled massless scalar field in the vicinity of a nonrotating black hole event horizon through the KGB quantization, in this work, we explicitly prove that the hole produces black-body radiation which its temperature exactly coincides with the result obtained by Hawking for black hole radiation.

  1. Spectrum of perturbations arising in a nonsingular model of the Universe with the initial de Sitter stage and the anisotropy of the relic radiation

    International Nuclear Information System (INIS)

    Starobinskij, A.A.

    1983-01-01

    Spectrum of primary adiabatic perturbations and gravitational waves formed in the proposed earlier by the author nonsingular cosmological model with the initial quantum de Sitter stage generated by gravitational vacuum polarization is calculated. The spectrum of gravitational waves appears to be flat, the spectrum of adiabatic perturbations is close to the flat one. The large-scale anisotropy of the temperature T of the relic electromagnetic radiation due to these fluctuations is found. It is shown that the most promising way to detect the anisotropy in the case of a flat perturbation spectrum is the investigation of correlations of ΔT/T at the angles of 5 deg - 10 deg

  2. A New General Tortoise Coordinate Transformation and Quantum Tunneling Effect of the Non-Stationary Higher Dimensional Vaidya-de Sitter Black Hole

    Science.gov (United States)

    Feng, Zhong-wen; Li, Guo-ping; Zhang, Yan; Zu, Xiao-tao

    2015-02-01

    In this paper, we combine the Hamilton-Jacobi equation with a new general tortoise coordinate transformation to study quantum tunneling of scalar particles and fermions from the non-stationary higher dimensional Vaidya-de Sitter black hole. The results show that Hamilton-Jacobi equation is a semi-classical foundation equation which can easily derived from the particles' dynamic equations, it can helps us understand the origin of Hawking radiation. Besides, based on the dimensional analysis, we believed that the new general tortoise coordinate transformation is more reasonable than old ones.

  3. Notes on Conservation Laws, Equations of Motion of Matter, and Particle Fields in Lorentzian and Teleparallel de Sitter Space-Time Structures

    Directory of Open Access Journals (Sweden)

    Waldyr A. Rodrigues

    2016-01-01

    Full Text Available We discuss the physics of interacting fields and particles living in a de Sitter Lorentzian manifold (dSLM, a submanifold of a 5-dimensional pseudo-Euclidean (5dPE equipped with a metric tensor inherited from the metric of the 5dPE space. The dSLM is naturally oriented and time oriented and is the arena used to study the energy-momentum conservation law and equations of motion for physical systems living there. Two distinct de Sitter space-time structures MdSL and MdSTP are introduced given dSLM, the first equipped with the Levi-Civita connection of its metric field and the second with a metric compatible parallel connection. Both connections are used only as mathematical devices. Thus, for example, MdSL is not supposed to be the model of any gravitational field in the General Relativity Theory (GRT. Misconceptions appearing in the literature concerning the motion of free particles in dSLM are clarified. Komar currents are introduced within Clifford bundle formalism permitting the presentation of Einstein equation as a Maxwell like equation and proving that in GRT there are infinitely many conserved currents. We prove that in GRT even when the appropriate Killing vector fields exist it is not possible to define a conserved energy-momentum covector as in special relativistic theories.

  4. Some investigations of null and time like geodesics in Schwarzschild and Schwarzschild de sitter black hole with a straight string passing through it

    International Nuclear Information System (INIS)

    Paudel, Eak Raj

    2007-01-01

    Gravitational field of Schwarzschild and Schwarzschild de-sitter Black hole with a straight string passing through it. In such space analytical and numerical solutions of null and time like geodesics are investigated. The string parameter a + is found to affect both the angle of deflection in null geodesics and the precession of perihelion on time like geodesics .It is seen that the deflection of null and time like geodesics near the gravitating mass of de-sitter space time increases with t he gravitational field of a straight string in flat space time has the property that the Newtonian potential vanishes yet there are non trivial gravitational effects. A test particle is neither attracted nor repelled by a string, yet the conical nature of space outside of string produces observable effects such as light deflection . Schwarzschild Black hole is a mathematical solution to the Einstein's field equations and corresponds to the gravitational field of massive compact spherically symmetric ob normal. References 1. Aryal, M.M, A. Vilenkin and L.H Ford, 1986, Phys.Rev. D32 ,2262 2. Moriyasu ,K ., 1980 , An introduction to gauge Invariance 3. Vilenkin A., 1985 , Physical reports , cosmic strings and Domain walls 4. Berry, M. , 1976 , Principle of cosmology and Gravitation 5. Mishner , C.W ., K.S .Throne , J.A wheeler , 1973. (Author)

  5. Explicit de Sitter flux vacua for global string models with chiral matter

    Science.gov (United States)

    Cicoli, Michele; Klevers, Denis; Krippendorf, Sven; Mayrhofer, Christoph; Quevedo, Fernando; Valandro, Roberto

    2014-05-01

    We address the open question of performing an explicit stabilisation of all closed string moduli (including dilaton, complex structure and Kähler moduli) in fluxed type IIB Calabi-Yau compactifications with chiral matter. Using toric geometry we construct Calabi-Yau manifolds with del Pezzo singularities. D-branes located at such singularities can support the Standard Model gauge group and matter content or some close extensions. In order to control complex structure moduli stabilisation we consider Calabi-Yau manifolds which exhibit a discrete symmetry that reduces the effective number of complex structure moduli. We calculate the corresponding periods in the symplectic basis of invariant three-cycles and find explicit flux vacua for concrete examples. We compute the values of the flux superpotential and the string coupling at these vacua. Starting from these explicit complex structure solutions, we obtain AdS and dS minima where the Kähler moduli are stabilised by a mixture of D-terms, non-perturbative and perturbative α ' corrections as in the LARGE Volume Scenario. In the considered example the visible sector lives at a dP6 singularity which can be higgsed to the phenomenologically interesting class of models at the dP3 singularity.

  6. Explicit de Sitter flux vacua for global string models with chiral matter

    Energy Technology Data Exchange (ETDEWEB)

    Cicoli, Michele [Dipartimento di Fisica e Astronomia, Università di Bologna, via Irnerio 46, 40126 Bologna (Italy); INFN, Sezione di Bologna, via Irnerio 46, 40126 Bologna (Italy); ICTP, Strada Costiera 11, 34014 Trieste (Italy); Klevers, Denis [Department of Physics and Astronomy, University of Pennsylvania, 209 South 33rd Street, Philadelphia, PA 19104-6396 (United States); Krippendorf, Sven [Bethe Center for Theoretical Physics and Physikalisches Institut der Universität Bonn, Nussallee 12, 53115 Bonn (Germany); Mayrhofer, Christoph [Institut für Theoretische Physik, Universität Heidelberg, Philosophenweg 19, 69120 Heidelberg (Germany); Quevedo, Fernando [ICTP, Strada Costiera 11, 34014 Trieste (Italy); DAMTP, University of Cambridge, Wilberforce Road, Cambridge, CB3 0WA (United Kingdom); Valandro, Roberto [ICTP, Strada Costiera 11, 34014 Trieste (Italy); INFN, Sezione di Trieste, Trieste (Italy)

    2014-05-05

    We address the open question of performing an explicit stabilisation of all closed string moduli (including dilaton, complex structure and Kähler moduli) in fluxed type IIB Calabi-Yau compactifications with chiral matter. Using toric geometry we construct Calabi-Yau manifolds with del Pezzo singularities. D-branes located at such singularities can support the Standard Model gauge group and matter content or some close extensions. In order to control complex structure moduli stabilisation we consider Calabi-Yau manifolds which exhibit a discrete symmetry that reduces the effective number of complex structure moduli. We calculate the corresponding periods in the symplectic basis of invariant three-cycles and find explicit flux vacua for concrete examples. We compute the values of the flux superpotential and the string coupling at these vacua. Starting from these explicit complex structure solutions, we obtain AdS and dS minima where the Kähler moduli are stabilised by a mixture of D-terms, non-perturbative and perturbative α{sup ′} corrections as in the LARGE Volume Scenario. In the considered example the visible sector lives at a dP{sub 6} singularity which can be higgsed to the phenomenologically interesting class of models at the dP{sub 3} singularity.

  7. Renormalization Group Flows from Holography-Supersymmetry and a c-Theorem

    CERN Document Server

    Freedman, D.Z.; Pilch, K.; Warner, N.P.

    1999-01-01

    We obtain first order equations that determine a supersymmetric kink solution in five-dimensional N=8 gauged supergravity. The kink interpolates between an exterior anti-de Sitter region with maximal supersymmetry and an interior anti-de Sitter region with one quarter of the maximal supersymmetry. One eighth of supersymmetry is preserved by the kink as a whole. We interpret it as describing the renormalization group flow in N=4 super-Yang-Mills theory broken to an N=1 theory by the addition of a mass term for one of the three adjoint chiral superfields. A detailed correspondence is obtained between fields of bulk supergravity in the interior anti-de Sitter region and composite operators of the infrared field theory. We also point out that the truncation used to find the reduced symmetry critical point can be extended to obtain a new N=4 gauged supergravity theory holographically dual to a sector of N=2 gauge theories based on quiver diagrams. We consider more general kink geometries and construct a c-function...

  8. Elementos básicos de salud infantil en mujeres cuidadoras de niños Basic elements of child health in baby sitters

    Directory of Open Access Journals (Sweden)

    José M. Hernández Hernández

    2004-12-01

    Full Text Available Se realizó estudio descriptivo prospectivo en mujeres cuidadoras de niños en el área de salud de Cabezas, provincia Matanzas, en el período octubre 2002 - marzo 2003, con el objetivo de valorar aspectos vinculados a la cultura sanitaria en relación con la salud infantil. Se aplicó una encuesta para evaluar el cuidado de la enfermedad diarreica aguda, la enfermedad respiratoria aguda, la conducta ante cuadros febriles, uso de antibióticos y otros temas. Se apreció que sólo el 30,86 % de las cuidadoras obtuvo una valoración adecuada respecto al tratamiento de estas afecciones y problemas. En la atención a la enfermedad diarreica aguda y la enfermedad respiratoria aguda se encontró un mayor nivel de conocimientos con respecto a los otros temas. La identificación de síntomas y signos de alarma ante la fiebre, la aplicación de medidas higiénicas para la prevención de la sepsis urinaria en las hembras, la ingestión de agua hervida y la atención adecuada de la fiebre, fueron las temáticas con menor dominio.A descriptive and prospective study was conducted among baby sitters in the health area of Cabezas, province of Matanzas, from October 2002 to March 2003, to assess aspects connected with the health culture in the field of children's health. A survey was done to evaluate the care of acute diarrheal disease, acute respiratory disease, the conduct followed in febrile pictures, use of antibiotics and other topics. It was found that only 30.86 % of these women had an adequate assessment concernign these affections and problems. It was observed a higher level of knowledge in the acute diarrheal disease and in the acute respiratory disease compared with other topics. The identification of symptoms and signs of alarm in the case of fever, the application of health measures for preventing urinary sepsis in the females, the ingestion of boiled water and the appropiate attention to fever were the topics with less control.

  9. Thermodynamics of Born-Infeld-anti-de Sitter black holes in the grand canonical ensemble

    International Nuclear Information System (INIS)

    Fernando, Sharmanthie

    2006-01-01

    The main objective of this paper is to study thermodynamics and stability of static electrically charged Born-Infeld black holes in AdS space in D=4. The Euclidean action for the grand canonical ensemble is computed with the appropriate boundary terms. The thermodynamical quantities such as the Gibbs free energy, entropy and specific heat of the black holes are derived from it. The global stability of black holes are studied in detail by studying the free energy for various potentials. For small values of the potential, we find that there is a Hawking-Page phase transition between a BIAdS black hole and the thermal-AdS space. For large potentials, the black hole phase is dominant and is preferred over the thermal-AdS space. Local stability is studied by computing the specific heat for constant potentials. The nonextreme black holes have two branches: small black holes are unstable and the large black holes are stable. The extreme black holes are shown to be stable both globally as well as locally. In addition to the thermodynamics, we also show that the phase structure relating the mass M and the charge Q of the black holes is similar to the liquid-gas-solid phase diagram

  10. One-loop effective action and Schwinger effect in (anti-) de Sitter space

    Science.gov (United States)

    Cai, Rong-Gen; Kim, Sang Pyo

    2014-09-01

    We study the Schwinger mechanism by a uniform electric field in dS2 and AdS2 and the curvature effect on the Schwinger effect, and further propose a thermal interpretation of the Schwinger formula in terms of the Gibbons-Hawking temperature and the Unruh temperature for an accelerating charge in dS2 and an analogous expression in AdS2. The exact one-loop effective action is found in the proper-time integral in each space, which is determined by the effective mass, the Maxwell scalar, and the scalar curvature, and whose pole structure gives the imaginary part of the effective action and the exact pair-production rate. The exact pair-production rate is also given the thermal interpretation.

  11. The large dimension limit of a small black hole instability in anti-de Sitter space

    Science.gov (United States)

    Herzog, Christopher P.; Kim, Youngshin

    2018-02-01

    We study the dynamics of a black hole in an asymptotically AdS d × S d space-time in the limit of a large number of dimensions, d → ∞. Such a black hole is known to become dynamically unstable below a critical radius. We derive the dispersion relation for the quasinormal mode that governs this instability in an expansion in 1 /d. We also provide a full nonlinear analysis of the instability at leading order in 1 /d. We find solutions that resemble the lumpy black spots and black belts previously constructed numerically for small d, breaking the SO( d + 1) rotational symmetry of the sphere down to SO( d). We are also able to follow the time evolution of the instability. Due possibly to limitations in our analysis, our time dependent simulations do not settle down to stationary solutions. This work has relevance for strongly interacting gauge theories; through the AdS/CFT correspondence, the special case d = 5 corresponds to maximally supersymmetric Yang-Mills theory on a spatial S 3 in the microcanonical ensemble and in a strong coupling and large number of colors limit.

  12. Gyromagnetic ratio of charged Kerr-anti-de Sitter black holes

    International Nuclear Information System (INIS)

    Aliev, Alikram N

    2007-01-01

    We examine the gyromagnetic ratios of rotating and charged AdS black holes in four and higher spacetime dimensions. We compute the gyromagnetic ratio for Kerr-AdS black holes with an arbitrary electric charge in four dimensions and show that it corresponds to g = 2 irrespective of the AdS nature of the spacetime. We also compute the gyromagnetic ratio for Kerr-AdS black holes with a single angular momentum and with a test electric charge in all higher dimensions. The gyromagnetic ratio crucially depends on the dimensionless ratio of the rotation parameter to the curvature radius of the AdS background. At the critical limit, when the boundary Einstein universe is rotating at the speed of light, it exhibits a striking feature leading to g 2 regardless of the spacetime dimension. Next, we extend our consideration to include the exact metric for five-dimensional rotating charged black holes in minimal gauged supergravity. We show that the value of the gyromagnetic ratio found in the 'test-charge' approach remains unchanged for these black holes

  13. Characterizing asymptotically anti-de Sitter black holes with abundant stable gauge field hair

    International Nuclear Information System (INIS)

    Shepherd, Ben L; Winstanley, Elizabeth

    2012-01-01

    In the light of the 'no-hair' conjecture, we revisit stable black holes in su(N) Einstein-Yang-Mills theory with a negative cosmological constant Λ. These black holes are endowed with copious amounts of gauge field hair, and we address the question of whether these black holes can be uniquely characterized by their mass and a set of global non-Abelian charges defined far from the black hole. For the su(3) case, we present numerical evidence that stable black hole configurations are fixed by their mass and two non-Abelian charges. For general N, we argue that the mass and N - 1 non-Abelian charges are sufficient to characterize large stable black holes, in keeping with the spirit of the 'no-hair' conjecture, at least in the limit of very large |Λ| and for a subspace containing stable black holes (and possibly some unstable ones as well). (paper)

  14. The rest mass of an asymptotically Anti-de Sitter spacetime

    OpenAIRE

    Chen, Po-Ning; Hung, Pei-Ken; Wang, Mu-Tao; Yau, Shing-Tung

    2015-01-01

    We study the space of Killing fields on the four dimensional AdS spacetime $AdS^{3,1}$. Two subsets $\\mathcal{S}$ and $\\mathcal{O}$ are identified: $\\mathcal{S}$ (the spinor Killing fields) is constructed from imaginary Killing spinors, and $\\mathcal{O}$ (the observer Killing fields) consists of all hypersurface orthogonal, future timelike unit Killing fields. When the cosmology constant vanishes, or in the Minkowski spacetime case, these two subsets have the same convex hull in the space of ...

  15. Asymptotically spacelike warped anti-de Sitter spacetimes in generalized minimal massive gravity

    Science.gov (United States)

    Setare, M. R.; Adami, H.

    2017-06-01

    In this paper we show that warped AdS3 black hole spacetime is a solution of the generalized minimal massive gravity (GMMG) and introduce suitable boundary conditions for asymptotically warped AdS3 spacetimes. Then we find the Killing vector fields such that transformations generated by them preserve the considered boundary conditions. We calculate the conserved charges which correspond to the obtained Killing vector fields and show that the algebra of the asymptotic conserved charges is given as the semi direct product of the Virasoro algebra with U(1) current algebra. We use a particular Sugawara construction to reconstruct the conformal algebra. Thus, we are allowed to use the Cardy formula to calculate the entropy of the warped black hole. We demonstrate that the gravitational entropy of the warped black hole exactly coincides with what we obtain via Cardy’s formula. As we expect, the warped Cardy formula also gives us exactly the same result as we obtain from the usual Cardy’s formula. We calculate mass and angular momentum of the warped black hole and then check that obtained mass, angular momentum and entropy to satisfy the first law of the black hole mechanics. According to the results of this paper we believe that the dual theory of the warped AdS3 black hole solution of GMMG is a warped CFT.

  16. Perturbative quantization of superstring theory in Anti de-Sitter spaces

    Energy Technology Data Exchange (ETDEWEB)

    Sundin, Per

    2010-07-12

    In this thesis we study superstring theory on AdS{sub 5} x S{sup 5}, AdS{sub 3} x S{sup 3} and AdS{sub 4} x CP{sub 3}. A shared feature of each theory is that their corresponding symmetry algebras allows for a decomposition under a Z{sub 4} grading. The grading can be realized through an automorphism which allows for a convenient construction of the string Lagrangians directly in terms of graded components. We adopt a uniform light-cone gauge and expand in a near plane wave limit, or equivalently, an expansion in transverse string coordinates. With a main focus on the two critical string theories, we perform a perturbative quantization up to quartic order in the number of fields. Each string theory is, through holographic descriptions, conjectured to be dual to lower dimensional gauge theories. The conjectures imply that the conformal dimensions of single trace operators in gauge theory should be equal to the energy of string states. What is more, through the use of integrable methods, one can write down a set of Bethe equations whose solutions encode the full spectral problem. One main theme of this thesis is to match the predictions of these equations, written in a language suitable for the light-cone gauge we employ, against explicit string theory calculations. We do this for a large class of string states and the perfect agreement we find lends strong support for the validity of the conjectures. (orig.)

  17. Asymptotically spacelike warped anti-de Sitter spacetimes in generalized minimal massive gravity

    International Nuclear Information System (INIS)

    Setare, M R; Adami, H

    2017-01-01

    In this paper we show that warped AdS 3 black hole spacetime is a solution of the generalized minimal massive gravity (GMMG) and introduce suitable boundary conditions for asymptotically warped AdS 3 spacetimes. Then we find the Killing vector fields such that transformations generated by them preserve the considered boundary conditions. We calculate the conserved charges which correspond to the obtained Killing vector fields and show that the algebra of the asymptotic conserved charges is given as the semi direct product of the Virasoro algebra with U (1) current algebra. We use a particular Sugawara construction to reconstruct the conformal algebra. Thus, we are allowed to use the Cardy formula to calculate the entropy of the warped black hole. We demonstrate that the gravitational entropy of the warped black hole exactly coincides with what we obtain via Cardy’s formula. As we expect, the warped Cardy formula also gives us exactly the same result as we obtain from the usual Cardy’s formula. We calculate mass and angular momentum of the warped black hole and then check that obtained mass, angular momentum and entropy to satisfy the first law of the black hole mechanics. According to the results of this paper we believe that the dual theory of the warped AdS 3 black hole solution of GMMG is a warped CFT. (paper)

  18. Symmetry analysis and conservation laws of the geodesic equations for the Reissner-Nordström de Sitter black hole with a global monopole

    Science.gov (United States)

    Nadjafikhah, Mehdi; Ahangari, Fatemeh

    2012-06-01

    This paper is devoted to the comprehensive analysis of the problem of symmetries and conservation laws for the geodesic equations of the Reissner-Nordström de Sitter (RNdS) black hole with a global monopole. For this purpose, the system of geodesic equations is determined and the corresponding classical Lie point symmetry operators are obtained. An optimal system of one dimensional subalgebras is constructed and a brief discussion about the algebraic structure of the Lie algebra of symmetries is presented. Also, the Noether symmetries of the geodesic Lagrangian is calculated. Finally, by applying two methods including Noether's theorem and direct method the conservation laws associated to the system of geodesic equations are obtained.

  19. Católicos antifascistas en Argentina (1936-1943. Luigi Sturzo y las tramas locales de People & Freedom Group. Anti-fascists Catholics in Argentina (1936-1943: Luigi Sturzo and the Local Relations of the People & Freedom Group

    Directory of Open Access Journals (Sweden)

    Diego Mauro

    2017-09-01

    Full Text Available El artículo se centra en una de las vertientes del antifascismo católico argentino de las décadas de 1930 y 1940: la del Partido Popular de Buenos Aires. En particular se analiza el impulso dado a la creación a nivel local de una sección de People and Freedom Group, una organización antifascista internacional impulsada por Luigi Sturzo durante su exilio en Londres y Estados Unidos. La breve experiencia de la sección local, que no sobrevivió al proceso mismo de conformación, sirve de plataforma para analizar las divergencias ideológicas y políticas que atravesaron a los diferentes grupos de católicos antifascistas en el país.

  20. Modelling duality between bound and resonant meson spectra by means of free quantum motions on the de Sitter space-time dS{sub 4}

    Energy Technology Data Exchange (ETDEWEB)

    Kirchbach, M. [UASLP, Instituto de Fisica, San Luis Potosi (Mexico); Compean, C.B. [Instituto Tecnologico de San Luis Potosi, San Luis Potosi (Mexico)

    2016-07-15

    The real parts of the complex squared energies defined by the resonance poles of the transfer matrix of the Poeschl-Teller barrier, are shown to equal the squared energies of the levels bound within the trigonometric Scarf well potential. By transforming these potentials into parts of the Laplacians describing free quantum motions on the mutually orthogonal open-time-like hyperbolic-, and closed-space-like spherical geodesics on the conformally invariant de Sitter space-time, dS{sub 4}, the conformal symmetries of these interactions are revealed. On dS{sub 4} the potentials under consideration naturally relate to interactions within colorless two-body systems and to cusped Wilson loops. In effect, with the aid of the dS{sub 4} space-time as unifying geometry, a conformal symmetry based bijective correspondence (duality) between bound and resonant meson spectra is established at the quantum mechanics level and related to confinement understood as color charge neutrality. The correspondence allows to link the interpretation of mesons as resonance poles of a scattering matrix with their complementary description as states bound by an instantaneous quark interaction and to introduce a conformal symmetry based classification scheme of mesons. As examples representative of such a duality we organize in good agreement with data 71 of the reported light flavor mesons with masses below ∝ 2350 MeV into four conformal families of particles placed on linear f{sub 0}, π, η, and a{sub 0} resonance trajectories, plotted on the l/M plane. Upon extending the sec{sup 2} χ by a properly constructed conformal color dipole potential, shaped after a tangent function, we predict the masses of 12 ''missing'' mesons. We furthermore notice that the f{sub 0} and π trajectories can be viewed as chiral partners, same as the η and a{sub 0} trajectories, an indication that chiral symmetry for mesons is likely to be realized in terms of parity doubled conformal

  1. [Detection and analysis of anti-Rh blood group antibodies].

    Science.gov (United States)

    Wu, Yuan-jun; Wu, Yong; Chen, Bao-chan; Liu, Yan

    2008-06-01

    To study the prevalence and distribution of anti-Rh blood group antibodies in Chinese population and its clinical significance. Irregular antibodies were screened and identified by Microcolum Gel Coomb's test. For those identified as positive anti-Rh samples, monoclonal antibodies (anti-D, -C, -c, -E and -e) were used to identify the specific antigen and confirm the accuracy of the irregular antibody tests. The titers, Ig-types and 37 Degrees Celsius-reactivity were tested to confirm its clinical significance. For evaluation of the origin of irregular antibodies, histories of pregnancy and transfusion were reviewed. For the newborns who had positive antibodies, their mothers were tested simultaneously to confirm the origin of the antibodies. 47 out of 54 000 (0.087%) patients were identified as positive with Rh blood group antibodies.Of them, 27 cases had history of pregnancy, 13 had transfusion and 1 had the histories of both. 6 newborns had antibodies derived form their mothers. The specificity of the antibody was as follows: 29 with anti-E (61.70%), 8 with anti-D (17.02%), anti-cE 5(10.64%), 4 with anti-c (8.51%) and 1 with anti-C (2.13%). All the 47 Rh blood group antibodies were IgG or IgG+IgM, and were reactive to red blood cells with corresponding antigens at 37 Degrees Celsius, with a highest titer of 1:4 096. The prevalence of Rh antibodies is lower in Chinese population as compared with that in White population.Of all the antibodies, anti-E is most frequently identified and anti-D was declining. Alloimmunization by pregnancy and transfusion is the major cause of Rh antibody production. Rh blood group antibodies derived from mothers are the major cause of Non-ABO-HDN.

  2. Anti-Kählerian Geometry on Lie Groups

    Science.gov (United States)

    Fernández-Culma, Edison Alberto; Godoy, Yamile

    2018-03-01

    Let G be a Lie group of even dimension and let ( g, J) be a left invariant anti-Kähler structure on G. In this article we study anti-Kähler structures considering the distinguished cases where the complex structure J is abelian or bi-invariant. We find that if G admits a left invariant anti-Kähler structure ( g, J) where J is abelian then the Lie algebra of G is unimodular and ( G, g) is a flat pseudo-Riemannian manifold. For the second case, we see that for any left invariant metric g for which J is an anti-isometry we obtain that the triple ( G, g, J) is an anti-Kähler manifold. Besides, given a left invariant anti-Hermitian structure on G we associate a covariant 3-tensor 𝜃 on its Lie algebra and prove that such structure is anti-Kähler if and only if 𝜃 is a skew-symmetric and pure tensor. From this tensor we classify the real 4-dimensional Lie algebras for which the corresponding Lie group has a left invariant anti-Kähler structure and study the moduli spaces of such structures (up to group isomorphisms that preserve the anti-Kähler structures).

  3. Loop groups in Yang–Mills theory

    Directory of Open Access Journals (Sweden)

    Alexander D. Popov

    2015-09-01

    Full Text Available We consider the Yang–Mills equations with a matrix gauge group G on the de Sitter dS4, anti-de Sitter AdS4 and Minkowski R3,1 spaces. On all these spaces one can introduce a doubly warped metric in the form ds2=−du2+f2dv2+h2dsH22, where f and h are the functions of u and dsH22 is the metric on the two-dimensional hyperbolic space H2. We show that in the adiabatic limit, when the metric on H2 is scaled down, the Yang–Mills equations become the sigma-model equations describing harmonic maps from a two-dimensional manifold (dS2, AdS2 or R1,1, respectively into the based loop group ΩG=C∞(S1,G/G of smooth maps from the boundary circle S1=∂H2 of H2 into the gauge group G. For compact groups G these harmonic map equations are reduced to equations of geodesics on ΩG, solutions of which yield magnetic-type configurations of Yang–Mills fields. The group ΩG naturally acts on their moduli space.

  4. Loop groups in Yang-Mills theory

    Science.gov (United States)

    Popov, Alexander D.

    2015-09-01

    We consider the Yang-Mills equations with a matrix gauge group G on the de Sitter dS4, anti-de Sitter AdS4 and Minkowski R 3 , 1 spaces. On all these spaces one can introduce a doubly warped metric in the form ds2 = - du2 +f2 dv2 +h2 d s H2 2 , where f and h are the functions of u and d s H2 2 is the metric on the two-dimensional hyperbolic space H2. We show that in the adiabatic limit, when the metric on H2 is scaled down, the Yang-Mills equations become the sigma-model equations describing harmonic maps from a two-dimensional manifold (dS2, AdS2 or R 1 , 1, respectively) into the based loop group ΩG =C∞ (S1 , G) / G of smooth maps from the boundary circle S1 = ∂H2 of H2 into the gauge group G. For compact groups G these harmonic map equations are reduced to equations of geodesics on ΩG, solutions of which yield magnetic-type configurations of Yang-Mills fields. The group ΩG naturally acts on their moduli space.

  5. The mechanical first law of black hole spacetimes with a cosmological constant and its application to the Schwarzschild-de Sitter spacetime

    International Nuclear Information System (INIS)

    Urano, Miho; Tomimatsu, Akira; Saida, Hiromi

    2009-01-01

    The mechanical first law (MFL) of black hole spacetimes is a geometrical relation which relates variations of the mass parameter and horizon area. While it is well known that the MFL of an asymptotic flat black hole is equivalent to its thermodynamical first law, however we do not know the detail of the MFL of black hole spacetimes with a cosmological constant which possess a black hole and cosmological event horizons. This paper aims to formulate an MFL of the two-horizon spacetimes. For this purpose, we try to include the effects of two horizons in the MFL. To do so, we make use of the Iyer-Wald formalism and extend it to regard the mass parameter and the cosmological constant as two independent variables which make it possible to treat the two horizons on the same footing. Our extended Iyer-Wald formalism preserves the existence of the conserved Noether current and its associated Noether charge, and gives an abstract form of the MFL of black hole spacetimes with a cosmological constant. Then, as a representative application of this formalism, we derive the MFL of the Schwarzschild-de Sitter (SdS) spacetime. Our MFL of the SdS spacetime relates the variations of three quantities: the mass parameter, the total area of the two horizons and the volume enclosed by the two horizons. If our MFL is regarded as a thermodynamical first law of the SdS spacetime, it offers a thermodynamically consistent description of the SdS black hole evaporation process: the mass decreases while the volume and the entropy increase. In our suggestion, a generalized second law is not needed to ensure the second law of SdS thermodynamics for its evaporation process.

  6. Addendum to: Modelling duality between bound and resonant meson spectra by means of free quantum motions on the de Sitter space-time dS{sub 4}

    Energy Technology Data Exchange (ETDEWEB)

    Kirchbach, M. [Instituto de Fisica, UASLP, San Luis Potosi (Mexico); Compean, C.B. [Instituto Tecnologico de San Luis Potosi, Soledad de Graciano Sanchez (Mexico)

    2017-04-15

    In the article under discussion the analysis of the spectra of the unflavored mesons lead us to some intriguing insights into the possible geometry of space-time outside the causal Minkowski light cone and into the nature of strong interactions. In applying the potential theory concept of geometrization of interactions, we showed that the meson masses are best described by a confining potential composed by the centrifugal barrier on the three-dimensional spherical space, S{sup 3}, and of a charge-dipole potential constructed from the Green function to the S{sup 3} Laplacian. The dipole potential emerged in view of the fact that S{sup 3} does not support single-charges without violation of the Gauss theorem and the superposition principle, thus providing a natural stage for the description of the general phenomenon of confined charge-neutral systems. However, in the original article we did not relate the charge-dipoles on S{sup 3} to the color neutral mesons, and did not express the magnitude of the confining dipole potential in terms of the strong coupling α{sub S} and the number of colors, N{sub c}, the subject of the addendum. To the amount S{sup 3} can be thought of as the unique closed space-like geodesic of a four-dimensional de Sitter space-time, dS{sub 4}, we hypothesized the space-like region outside the causal Einsteinian light cone (it describes virtual processes, among them interactions) as the (1+4)-dimensional subspace of the conformal (2+4) space-time, foliated with dS{sub 4} special relativity for strong interaction processes. The potential designed in this way predicted meson spectra of conformal degeneracy patterns, and in accord with the experimental observations. We now extract the α{sub s} values in the infrared from data on meson masses. The results obtained are compatible with the α{sub s} estimates provided by other approaches. (orig.)

  7. Characterization of Sulfate Groups and Assessment of Anti ...

    African Journals Online (AJOL)

    Fourier transform infrared FT-IR spectra, Laser Raman spectra and 13C Nuclear Magnetic Resonance NMR spectra were obtained and used to analyze the sulfate groups. The anti-coagulant activity of KOGM and KOGMS was evaluated in vitro using activated partial thromboplastin time (APTT), prothrombin time (PT) and ...

  8. Plan de negocios Oshian Group

    OpenAIRE

    Castillo Bolivar, Evelyn Johana; Charry López, Ingrid Milena

    2013-01-01

    Plan de negocios para crear una empresa de servicios de importación con contacto directo con proveedores y empresarios chinos para el sector de las Pymes Bogotanas. Oshian Group S.A.S., es una empresa importadora, ubicada en el barrio Chico; inicialmente operará en la ciudad de Bogotá, esto no limita el mercado sino que también se podrá expandir a clientes de otras ciudades del país en mediano o largo plazo. Diferentes sectores económicos como las Pymes han mostrado un avance a través de ...

  9. Terpaan Pesan Iklan Anti Kekerasan Radio PRAMBORS dan Interaksi Peer Group terhadap Sikap Anti Kekerasan Remaja

    Directory of Open Access Journals (Sweden)

    Ayang Fitrianti

    2017-07-01

    Full Text Available Characteristic teen expressive, always curious and receptive to new values in this era of globalization should be directed and escorted on positive things like Prambors Radio which serve Ad Links anti Violence. Therefore, this study aims to determine the extent of Exposure to Violence Ad Links Prambors Radio and Peer Group of the Attitudes of Teen Violence. The method used in this research is quantitative method, explanatory paradigm of positivistic. The theory used in this study is the Social Learning Theory by Bandura and the theory of Hierarchy Effect Model. This study uses survey respondents were 116 respondents who are listeners Prambors Radio. Based on this research, it can be concluded that the inundation Ad Links Anti Violence positively related to Attitude Teen Violence. In addition the results also showed that interaction with the Peer Group also showed a significant positive correlation to the attitude of Teen Violence.

  10. Anti-choice groups target reproductive rights in Congress.

    Science.gov (United States)

    1995-06-16

    In a May 3 memo, the GOP "Family Caucus" presented its legislative agenda for the remainder of the 104th Congress. Chaired by Representative Tom Coburn (R-OK), the anti-choice caucus promotes family and social issues, and emphasizes religious liberty and parental rights. It is seeking to eliminate funding for Title X of the Public Health Service Act, which provides grants to domestic family planning providers; repeal the Freedom of Access to Clinic Entrances Act (FACE); curtail fetal tissue research; restrict the production and sale of RU486; reduce funding for the US Agency for International Development (USAID); and hinder US representation at the UN Fourth World Conference on Women. On May 17, the Virginia-based Christian Coalition unveiled a ten-point "Contract with the American Family," which targets reproductive health care by restricting late-term abortions, reversing the Medicaid requirement that states cover abortions in cases of rape or incest, and eliminating funding for Title X and international family planning. Director Ralph Reed was joined at the group's press conference in the Capitol by Speaker of the House Newt Gingrich (R-GA) and Senator Phil Gramm (R-TX), both of whom are anti-abortion. Senate Majority Leader Robert Dole (R-KS), who is also anti-choice, met with Reed in his office later that day. Anti-choice representatives and senators met with some success in the last month in restricting US funding for family planning programs abroad, US participation in international meetings, and the performance of abortions at military facilities. Representative Charles Canady (R-FL) has introduced a bill banning modified dilation and evacuation abortions, and Representative Robert Dornan (R-CA) has introduced the "Family Planning Programs Repeal Act" (HR 1623).

  11. Anti-D3 branes and moduli in non-linear supergravity

    Science.gov (United States)

    Garcia del Moral, Maria P.; Parameswaran, Susha; Quiroz, Norma; Zavala, Ivonne

    2017-10-01

    Anti-D3 branes and non-perturbative effects in flux compactifications spontaneously break supersymmetry and stabilise moduli in a metastable de Sitter vacua. The low energy 4D effective field theory description for such models would be a supergravity theory with non-linearly realised supersymmetry. Guided by string theory modular symmetry, we compute this non-linear supergravity theory, including dependence on all bulk moduli. Using either a constrained chiral superfield or a constrained vector field, the uplifting contribution to the scalar potential from the anti-D3 brane can be parameterised either as an F-term or Fayet-Iliopoulos D-term. Using again the modular symmetry, we show that 4D non-linear supergravities that descend from string theory have an enhanced protection from quantum corrections by non-renormalisation theorems. The superpotential giving rise to metastable de Sitter vacua is robust against perturbative string-loop and α' corrections.

  12. Prevalence des hemolysines chez les donneurs de sang de groupe ...

    African Journals Online (AJOL)

    Objectifs : Déterminer la fréquence et le titre des hémolysines anti-A et anti-B dans la population des donneurs O et de prédire de l'intérêt de la systématisation de leur recherche chez tous les donneurs O par l'évaluation du risque d'accident transfusionnels liés aux hémolysines. Méthodologie : Etude prospective au ...

  13. Anti-dsdna, anti-smith y anti-la: Factores de riesgo y pronóstico de nefritis lúpica

    OpenAIRE

    Roberto Ferro; Francisco Medina; Demetrio Serracín

    2006-01-01

    Introducción:La nefritis lúpica es una manifestación común y de mal pronóstico en pacientes con lupus eritematoso sistémico. Diferentes; autoanticuerpos han mostrado relación con la aparición nefritis lúpica pero los resultados son controversiales. En la presente investigación; se estudian los factores inmunológicos asociados a la aparición y grado morfológico de nefritis lúpica, tales como el anticuerpo anti-dsDNA,; anti-Sm, anti-Ro y anti-La y anti-RNP. Materiales y Métodos:Estudio...

  14. Investigating GM Risk Perceptions: A Survey of Anti-GM and Environmental Campaign Group Members

    Science.gov (United States)

    Hall, Clare; Moran, Dominic

    2006-01-01

    This study investigates how members of anti-GM campaign groups and environment groups perceive the risks and benefits of genetically modified (GM) technology in food and agriculture. The study targeted these groups as the most risk-averse sector of society when considering GM technology. Survey respondents were asked to rank the current and future…

  15. Extremal limits of the C metric: Nariai, Bertotti-Robinson, and anti-Nariai C metrics

    International Nuclear Information System (INIS)

    Dias, Oscar J.C.; Lemos, Jose P.S.

    2003-01-01

    In two previous papers we have analyzed the C metric in a background with a cosmological constant Λ, namely, the de-Sitter (dS) C metric (Λ>0), and the anti-de Sitter (AdS) C metric (Λ 0, Λ=0, and Λ 2 xS-tilde 2 ) to each point in the deformed two-sphere S-tilde 2 corresponds a dS 2 spacetime, except for one point which corresponds to a dS 2 spacetime with an infinite straight strut or string. There are other important new features that appear. One expects that the solutions found in this paper are unstable and decay into a slightly nonextreme black hole pair accelerated by a strut or by strings. Moreover, the Euclidean version of these solutions mediate the quantum process of black hole pair creation that accompanies the decay of the dS and AdS spaces

  16. Uso de los antisépticos en atención primaria

    Directory of Open Access Journals (Sweden)

    M. Isabel Gutiérrez Pérez

    2014-05-01

    Otro uso de los antisépticos es el cuidado de heridas producidas por la implantación de objetos dentro de la estética corporal (piercing y similares, siendo recomendable el empleo de antisépticos transparentes que permitan observar la evolución de la técnica.

  17. Interactions among social monitoring, anti-predator vigilance and group size in eastern grey kangaroos.

    Science.gov (United States)

    Favreau, François-René; Goldizen, Anne W; Pays, Olivier

    2010-07-07

    Group size is known to affect both the amount of time that prey animals spend in vigilance and the degree to which the vigilance of group members is synchronized. However, the variation in group-size effects reported in the literature is not yet understood. Prey animals exhibit vigilance both to protect themselves against predators and to monitor other group members, and both forms of vigilance presumably influence group-size effects on vigilance. However, our understanding of the patterns of individual investment underlying the time sharing between anti-predator and social vigilance is still limited. We studied patterns of variation in individual vigilance and the synchronization of vigilance with group size in a wild population of eastern grey kangaroos (Macropus giganteus) subject to predation, in particular focusing on peripheral females because we expected that they would exhibit both social and anti-predator vigilance. There was no global effect of group size on individual vigilance. The lack of group-size effect was the result of two compensating effects. The proportion of time individuals spent looking at other group members increased, whereas the proportion of time they spent scanning the environment decreased with group size; as a result, overall vigilance levels did not change with group size. Moreover, a degree of synchrony of vigilance occurred within groups and that degree increased with the proportion of vigilance time peripheral females spent in anti-predator vigilance. Our results highlight the crucial roles of both social and anti-predator components of vigilance in the understanding of the relationship between group size and vigilance, as well as in the synchronization of vigilance among group members.

  18. Modern Sociotechnology: Set by De Sitter

    NARCIS (Netherlands)

    Benders, J.G.J.M.; Doorewaard, J.A.C.M.; Poutsma, F.

    2000-01-01

    Paradoxically, the notion ofnew work organizations has a long history, in particular in the Netherlands . To understand this, it is necessary to make a distinction between the accidental experiments with new forms of work, such as team-based working, on the one hand, and the acceptance ofthese

  19. Newton's law in de Sitter brane

    International Nuclear Information System (INIS)

    Ghoroku, Kazuo; Nakamura, Akihiro; Yahiro, Masanobu

    2003-01-01

    Newton potential has been evaluated for the case of dS brane embedded in Minkowski, dS 5 and AdS 5 bulks. We point out that only the AdS 5 bulk might be consistent with the Newton's law from the brane-world viewpoint when we respect a small cosmological constant observed at present universe

  20. De Sitter vacua of strongly interacting QFT

    Energy Technology Data Exchange (ETDEWEB)

    Buchel, Alex [Department of Applied Mathematics, University of Western Ontario,London, Ontario N6A 5B7 (Canada); Department of Physics and Astronomy, University of Western Ontario,London, Ontario N6A 5B7 (Canada); Perimeter Institute for Theoretical Physics,Waterloo, Ontario N2J 2W9 (Canada); Karapetyan, Aleksandr [Department of Applied Mathematics, University of Western Ontario,London, Ontario N6A 5B7 (Canada)

    2017-03-22

    We use holographic correspondence to argue that Euclidean (Bunch-Davies) vacuum is a late-time attractor of the dynamical evolution of quantum gauge theories at strong coupling. The Bunch-Davies vacuum is not an adiabatic state, if the gauge theory is non-conformal — the comoving entropy production rate is nonzero. Using the N=2{sup ∗} gauge theory holography, we explore prospects of explaining current accelerated expansion of the Universe as due to the vacuum energy of a strongly coupled QFT.

  1. Therapeutic potential of an anti-high mobility group box-1 monoclonal antibody in epilepsy.

    Science.gov (United States)

    Zhao, Junli; Wang, Yi; Xu, Cenglin; Liu, Keyue; Wang, Ying; Chen, Liying; Wu, Xiaohua; Gao, Feng; Guo, Yi; Zhu, Junming; Wang, Shuang; Nishibori, Masahiro; Chen, Zhong

    2017-08-01

    Brain inflammation is a major factor in epilepsy, and the high mobility group box-1 (HMGB1) protein is known to contribute significantly to the generation of seizures. Here, we investigated the therapeutic potential of an anti-HMGB1 monoclonal antibody (mAb) in epilepsy. anti-HMGB1 mAb attenuated both acute seizure models (maximal electroshock seizure, pentylenetetrazole-induced and kindling-induced), and chronic epilepsy model (kainic acid-induced) in a dose-dependent manner. Meanwhile, the anti-HMGB1 mAb also attenuated seizure activities of human brain slices obtained from surgical resection from drug-resistant epilepsy patients. The mAb showed an anti-seizure effect with a long-term manner and appeared to be minimal side effects at even very high dose (no disrupted physical EEG rhythm and no impaired basic physical functions, such as body growth rate and thermoregulation). This anti-seizure effect of mAb results from its inhibition of translocated HMGB1 from nuclei following seizures, and the anti-seizure effect was absent in toll-like receptor 4 knockout (TLR4 -/- ) mice. Interestingly, the anti-HMGB1 mAb also showed a disease-modifying anti-epileptogenetic effect on epileptogenesis after status epileptics, which is indicated by reducing seizure frequency and improving the impaired cognitive function. These results indicate that the anti-HMGB1 mAb should be viewed as a very promising approach for the development of novel therapies to treat refractory epilepsy. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. Geodesic Motion of Particles and Quantum Tunneling from Reissner-Nordström Black Holes in Anti-de Sitter Spacetime

    Science.gov (United States)

    Deng, Gao-Ming; Huang, Yong-Chang

    2018-03-01

    The geodesics of tunneling particles were derived unnaturally and awkwardly in previous works. For one thing, the previous derivation was inconsistent with the variational principle of action. Moreover, the definition of geodesic equations for massive particles was quite different from that of massless case. Even worse, the relativistic and nonrelativistic foundations were mixed with each other during the past derivation of geodesics. As a highlight, remedying the urgent shortcomings, we improve treatment to derive the geodesic equations of massive and massless particles in a unified and self-consistent way. Besides, we extend to investigate the Hawking radiation via tunneling from Reissner-Nordström black holes in the context of AdS spacetime. Of special interest, the trick of utilizing the first law of black hole thermodynamics manifestly simplifies the calculation of tunneling integration.

  3. Existence of topological hairy dyons and dyonic black holes in anti-de Sitter su(N) Einstein-Yang-Mills theory

    Energy Technology Data Exchange (ETDEWEB)

    Baxter, J. Erik, E-mail: e.baxter@shu.ac.uk [Department of Engineering and Mathematics, Sheffield Hallam University, Sheffield S11WB (United Kingdom)

    2016-02-15

    We investigate dyonic black hole and dyon solutions of four-dimensional su(N) Einstein-Yang-Mills theory with a negative cosmological constant. We derive a set of field equations in this case, and prove the existence of non-trivial solutions to these equations for any integer N, with 2N − 2 gauge degrees of freedom. We do this by showing that solutions exist locally at infinity, and at the event horizon for black holes and the origin for solitons. We then prove that we can patch these solutions together regularly into global solutions that can be integrated arbitrarily far into the asymptotic regime. Our main result is to show that dyonic solutions exist in open sets in the parameter space, and hence that we can find non-trivial dyonic solutions in a number of regimes whose magnetic gauge fields have no zeros, which is likely important to the stability of the solutions.

  4. Activité anti-inflammatoire de l'extrait aqueux des feuilles de Elaeis ...

    African Journals Online (AJOL)

    Elaeis guineensis est souvent utilisée en médecine traditionnelle africaine dans la prise en charge de nombreuses pathologies. Ces travaux avaient pour objectif de faire une étude phytochimique et de déterminer l'activité anti-inflammatoire de l'extrait aqueux des feuilles de Elaeis guineensis. Le modèle de l'oedème ...

  5. Non-association between anti-Toxoplasma gondii antibodies and ABO blood group system

    Directory of Open Access Journals (Sweden)

    ACF Rodrigues

    2011-01-01

    Full Text Available Toxoplasma gondii infects humans through the gastrointestinal tract (GIT, which elicits humoral immune response with specific antibodies. The expression of the ABO blood group glycoconjugates also occurs in this same system and may influence the human susceptibility of infection by T. gondii. The aim of the present study was to investigate the association between ABO blood group phenotypes and the presence of anti-T. gondii antibodies. Data - including age, results of serology tests for T. gondii infection and ABO blood group phenotypes - were assembled from the medical records of 1,006 pregnant women attended in the Base Hospital of the Medical School of São José do Rio Preto, Brazil, between 2001 and 2004. The chi-square test was used to compare the results with the level of significance set at 5%. Of the studied cases, 64.1% (645/1006 and 35.9% (391/1006 presented respectively positive and negative serology tests for anti-T. gondii antibodies. The mean age of those who tested positive was higher than those with negative serology tests (p = 0.0004. The frequencies of ABO blood group phenotypes were similar in those with and without anti-T. gondii antibodies (p = 0.35. In conclusion, the ABO blood group system is not associated with the presence or absence of anti-T. gondii antibodies.

  6. Pintores de hoy. Los Anti-Cristos

    Directory of Open Access Journals (Sweden)

    Mario Rivero

    1968-06-01

    Full Text Available Antonio Roda es un hombre que tiene un poder extraño: levanta la casa del hombre en el reino de los colores y rescata su imagen, esta segunda vez; quiero decir ahora, tal como están las cosas, cuando la pintura no puede hacerse como repetición con todo el color y la fijeza de la realidad y cuando me parece también que a todo pintor consciente le gustaría pensar, que tiene cierta utilidad social, mas directa.

  7. Neurobiologia do transtorno de personalidade anti-social Neurobiology of anti-social personality disorder

    Directory of Open Access Journals (Sweden)

    Cristina Marta Del-Ben

    2005-01-01

    Full Text Available Nos últimos anos, tem havido um interesse crescente a respeito de uma melhor compreensão sobre o comportamento anti-social. O aumento da criminalidade e violência urbanas pode ter contribuído para esse maior interesse. Além de fatores psicossociais, outros biológicos têm sido implicados na fisiopatogenia do transtorno de personalidade anti-social (TPAS. Estudos de neuroimagem apontam o envolvimento de estruturas cerebrais frontais, especialmente o córtex orbitofrontal, e a amígdala. Também tem sido sugerido que prejuízos na função serotonérgica estariam associados à ocorrência de comportamento anti-social, já que pacientes com diagnóstico de TPAS apresentam respostas hormonais atenuadas a desafios farmacológicos com drogas que aumentam a função serotonérgica cerebral e redução da concentração de receptores serotonérgicos. Uma abordagem ampla dos diferentes fatores possivelmente envolvidos na fisiopatogenia do TPAS poderia contribuir para o desenvolvimento de novas técnicas de prevenção e intervenção.Violence and crime have been increasing considerably in urban societies. As a consequence, some efforts have been made aiming at a better understanding of antisocial bevaviour. Apart from psychosocial factors, some evidences suggest the occurrence of biological factors in the pathogenesis of antisocial personality disorders (ASPD. Neuroimaging studies have shown the involvement of prefrontal areas, especially orbitofrontal cortex, and amygdala. Also, impaired serotonin (5-HT neurotransmission has been implicated, since patients with ASPD present alterations in measures of 5-Ht system, such as blunted hormonal response to 5-HT pharmacological challenges and reduced 5-HT receptors numbers. A comprehensive approach of antisocial behavior, including biological and psychosocial aspects could lead to the development of new techniques for prevention and intervention in ASPD.

  8. Holography in asymptotically flat spacetimes and the BMS group

    International Nuclear Information System (INIS)

    Arcioni, Giovanni; Dappiaggi, Claudio

    2004-01-01

    In a previous paper (Arcioni G and Dappiaggi C 2003 Preprint hep-th/0306142) we have started to explore the holographic principle in the case of asymptotically flat spacetimes and analysed, in particular, different aspects of the Bondi-Metzner-Sachs (BMS) group, namely the asymptotic symmetry group of any asymptotically flat spacetime. We continue this investigation in this paper. Having in mind an S-matrix approach with future and past null infinity playing the role of holographic screens on which the BMS group acts, we connect the IR sectors of the gravitational field with the representation theory of the BMS group. We analyse the (complicated) mapping between bulk and boundary symmetries pointing out differences with respect to the anti-de Sitter (AdS)/CFT set up. Finally, we construct a BMS phase space and a free Hamiltonian for fields transforming with respect to BMS representations. The last step is supposed to be an explorative investigation of the boundary data living on the degenerate null manifold at infinity

  9. Inflación Eterna y el Multiverso. Un estudio desde los problemas de la teoría del Big Bang hasta el Multiverso inflacionario.

    OpenAIRE

    Calvo Aurrekoetxea, Josu

    2017-01-01

    En este Trabajo Fin de Grado se hace un estudio de la Teoría de la Inflación Cósmica como solución de los problemas de la teoría del Big Bang a partir del acoplo gravitatorio de un campo escalar. Además, se analizan potenciales con mínimos con constante cosmológica positiva de Sitter (dS), negativa Anti-de Sitter (AdS) y las transiciones cosmológicas entre ellos. Por último, se presenta un modelo dS-dS para el cual el escenario final es una región con multiples universos inflacionarios; pudie...

  10. Enjuagues de Calendula officinalis como alternativa de los antisépticos orales

    Directory of Open Access Journals (Sweden)

    Luis Fang Mercado

    Full Text Available En la progresión de la enfermedad periodontal intervienen múltiples factores, incluyendo los diversos microorganismos orales que conforman la placa bacteriana o patógenos libres en cavidad oral que logran desencadenar una respuesta inmunológica e inflamatoria en el huésped. Existen herramientas químicas que combaten cualquier posibilidad de colonización e infección por parte de algún microorganismo. Los antisépticos orales son de gran utilidad especialmente luego de cirugías periodontales. Es allí donde su importancia se hace casi imprescindible, para controlar la noxa, pero a su vez deben facilitar el proceso de cicatrización de los tejidos involucrados. El objetivo del presente manuscrito consistió en reportar y describir un caso clínico donde el empleo de clorhexidina al 0,12 % como antiséptico oral postoperatorio no favoreció la cicatrización adecuada de los tejidos mucosos luego de realizarse un injerto gingival libre. Como alternativa antiséptica se prescribieron enjuagues a base de Caléndula, observándose cicatrización de los tejidos afectados a los pocos días de uso. Se discute que posterior a todo proceso operatorio de carácter quirúrgico se debe colocar en una balanza riesgo-beneficio, donde se escoge la posibilidad de evitar la infección posoperatoria o la cicatrización oportuna de esta. Los enjuagues orales de caléndula permitieron la cicatrización oportuna; los colutorios de caléndula contemplan una pequeña proporción de capacidad antimicrobiana y una alta habilidad inductora de la cicatrización tisular.

  11. The gas de France group in 2000

    International Nuclear Information System (INIS)

    Gadonneix, P.

    1999-01-01

    The speech by the Chairman of France's largest gas company is always a highlight of the Gas Conference's closing session. This year, Pierre Gadonneix outlined the gas supply context in which Gaz de France will be running its business operations, and revealed the group's development strategy in a Europe-wide market soon to become a reality, with the implementation of the gas directive in August 2000. (authors)

  12. Vergelijking vangstsamenstelling vernieuwd twinrigtuig voor de Osprey group

    NARCIS (Netherlands)

    Wijsman, J.W.M.; Ende, van den D.; Perdon, K.J.

    2014-01-01

    De Osprey group B.V. werkt aan de ontwikkeling van een nieuw netontwerp voor de twinrigvisserij met als doel de bodemberoering, de hoeveelheid discards en het brandstofverbruik te verminderen. Dit rapport beschrijft de resultaten van een vergelijkend visonderzoek dat is uitgevoerd in september 2014,

  13. Restricted mobility of specific functional groups reduces anti-cancer drug activity in healthy cells

    DEFF Research Database (Denmark)

    Longo Martins, Murillo; Ignazzi, Rosanna; Eckert, Juergen

    2016-01-01

    The most common cancer treatments currently available are radio- and chemo-therapy. These therapies have, however, drawbacks, such as, the reduction in quality of life and the low efficiency of radiotherapy in cases of multiple metastases. To lessen these effects, we have encapsulated an anti...... with reduced clearance rate and toxicity. X-rays and neutrons were used to investigate the carrier structure, as well as to assess the drug mobility within the bio-nanocomposite. From these unique data we show that partial mobility restriction of active groups of the drug molecule suggests why this carrier...

  14. Patrón de immunoblotting y niveles de anticuerpos anti-Toxoplasma gondii en suero y humor acuoso de pacientes con lesiones de toxoplasmosis ocular

    Directory of Open Access Journals (Sweden)

    Morella Bouchard Pereira

    2014-07-01

    Full Text Available El objetivo de este estudio fue evaluar en muestras de suero y humor acuoso los niveles de anticuerpos anti-toxoplasma a través del Coeficiente de Goldmann y Witmer (CGW y el patrón de reconocimiento antigénico a través del immunoblotting (IB, en pacientes con serología positiva con y sin lesiones de toxoplasmosis ocular. Se recogieron simultáneamente muestras de suero y humor acuoso de 26 pacientes: un grupo de casos que poseían lesiones retinales de toxoplasmosis ocular en fase activa e inactiva (n=17 y un grupo control que requería cirugía ocular por presencia de cataratas (n=9. Las determinación de IgM e IgG específicas se realizó por ELISA de inmunocaptura e indirecto, respectivamente. Se utilizó la inmunodifusión radial para la cuantificación de la IgG total. El CGW resultó >2, indicativo de producción local de anticuerpos específicos en 12/17 de los casos, mientras que en los controles no se observó, esto evidenció una sensibilidad del 71% y una especificidad de 100%. En IB, la aparición de bandas diferentes en humor acuoso, indicativo de producción local de anticuerpos específicos se observaron en 11/17 de los casos y 1/9 de los controles, reflejando una sensibilidad de 65% y una especificidad de 89%. Al considerar las dos pruebas la sensibilidad se incrementó a un 73%, pero la especificidad disminuyó a 89%. En conclusión el IB es útil como prueba confirmatoria para diagnóstico de toxoplasmosis ocular, pero sólo como un complemento del coeficiente de GW especialmente en pacientes con lesiones atípicas donde el diagnóstico clínico es difícil. Aqueous humor and serum immunoblotting profiles and anti–toxoplasma gondii antibodies in patients with toxoplasmosis-induced retinal lesions Abstract The purpose of this study was to analize the anti-Toxoplasma gondii antibodies levels in serum and aqueous humor samples in patients with ocular toxoplasmosis by using Goldman and Witmer Coefficient (GWC and the

  15. Metodología de pesquisa preclínica de actividad anti-herpesvirus a partir de productos naturales Methodology for the preclinical screening of anti-herpesvirus activity starting from natural products

    Directory of Open Access Journals (Sweden)

    Gloria del Barrio Alonso

    2008-08-01

    Full Text Available Herpesviridae es una de las familias virales de mayor impacto en la salud humana y animal. Los virus del herpes simple constituyen causa de infecciones muy comunes, con un amplio espectro de manifestaciones clínicas. La naturaleza latente de la infección que le permite al virus escapar de los efectores de la respuesta inmunológica, ha imposibilitado la obtención de vacunas antiherpéticas eficaces. Esto ha motivado la búsqueda de productos antiherpéticos, lo cual trae consigo la necesidad de establecer un sistema de evaluación preclínica de productos naturales y sintéticos mediante una metodología de pesquisa rápida in vitro. En el presente trabajo se muestra la metodología y fundamentación del sistema de ensayos empleado por el Grupo de Antivirales Naturales de la Facultad de Biología (Universidad de La Habana para el pesquisaje de productos con propiedades antiherpéticas. Dicha metodología incluye la evaluación primaria y varios ensayos secundarios, encaminados a la determinación de los mecanismos de acción.Herpesviridae is one of the viral families of greatest impact on human and animal health. HSVs are the etiological agents of very common infections associated with a broad range of clinical symptoms. The latent nature of the infection allows the virus to escape from immune responses, hindering the obtention of efficient anti-herpes vaccines. This fact has encouraged scientists to search new anti-herpes drugs, and that's why the establishment of a rapid methodology for the in vitro evaluation of new products with potential antiviral activity is urgently needed. In this work, we describe the complete guide followed by the Antiviral Natural Products Research Group (Faculty of Biology, University of Havana to perform the screening for antiviral activities among natural products. This guide includes the preliminary evaluation assay and a variety of secondary tests.

  16. Activities of Gaz de France Group

    International Nuclear Information System (INIS)

    Anon.

    2003-01-01

    The Board of Directors of Gaz de France approved the Group's consolidated accounts for 2004. In a more dynamic economic environment than in 2003, the Gaz de France Group reports enhanced results and has continued to pursue its growth in Europe. Increase in net sales driven by sustained growth in sales (+ 8.9%): In 2004, net sales rose 8.9% compared with the 2003 financial year to reach a total of euro 18,129 m. This strong increase in business activities was driven by sustained growth in sales volumes both in France and Europe. Total Group sales volumes amounted to 730 TWh (approximately 66 billion cubic metres), equal to growth of 10.3%. Natural gas sales volumes increased by approximately 10% in France, and are almost 18% higher in Europe, notably in the United Kingdom, Italy, Belgium and the Netherlands. The Group has pursued the profitable development of its activities outside France. As a result, international activities account for 29% of total sales in 2004, against 23% in 2003. The contribution made by international subsidiaries - particularly those specializing in exploration and production - grew by a very substantial 44.3% to reach a total of euro 502 m in 2004. Energy and Services Offering Branch: this core business line, which includes natural gas and oil exploration and production, energy trading and sales, and services associated with the supply of energy, boasts net sales of euro 16,498 m, equal to growth of 10.8% compared with 2003. Infrastructures Branch: this division, which groups together all activities related to the management of transmission and distribution infrastructures in both the French domestic and international markets, generated net sales of euro 6,794 m in 2004, virtually unchanged from the previous year. This situation is the result of higher sales generated by the distribution subsidiaries operating outside France (+9.2%) offset by a decline in the sales performance of the Transmission, Storage and Distribution in France

  17. Symmetries, Information and Monster Groups before and after the Big Bang

    Directory of Open Access Journals (Sweden)

    Arturo Tozzi

    2016-12-01

    Full Text Available The Monster group, the biggest of the sporadic groups, is equipped with the highest known number of dimensions and symmetries. Taking into account variants of the Borsuk–Ulam theorem and a novel topological approach cast in a physical fashion that has the potential to be operationalized, the universe can be conceived as a lower-dimensional manifold encompassed in the Monster group. Our universe might arise from spontaneous dimension decrease and symmetry breaking that occur inside the very structure of the Monster Module. We elucidate how the energetic loss caused by projection from higher to lower dimensions and by the Monster group’s non-abelian features is correlated with the present-day asymmetry in the thermodynamic arrow. By linking the Monster Module to its theoretical physical counterparts, it is then possible to calculate its enthalpy and Lie group trajectories. Our approach also reveals how a symmetry break might lead to a universe based on multi-dimensional string theories and CFT/AdS (anti-de Sitter/conformal field theory correspondence.

  18. Frecuencia de anticuerpos anti Trypanozoma cruzi en pacientes portadores de marcapasos de la Clinica San Pedro Claver de Bogotá

    Directory of Open Access Journals (Sweden)

    Guillermo Mora

    2007-12-01

    Conclusiones. La prevalencia de anticuerpos anti-T. cruzi en pacientes portadores de marcapaso es alta. La implantación de marcapasos se presentó más tempranamente en el grupo seropositivo. No hay adecuada sospecha clínica ni información al paciente sobre el diagnóstico de la enfermedad de Chagas.

  19. Bourses de l'International Crisis Group | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    L'International Crisis Group (Crisis Group) envisageait depuis longtemps de créer des bourses afin de permettre à un noyau d'analystes de se familiariser avec la méthodologie rigoureuse et éprouvée qui fait aujourd'hui la réputation du groupe. Cette subvention soutiendra la création de ces bourses. Les bourses seront ...

  20. Restricted mobility of specific functional groups reduces anti-cancer drug activity in healthy cells

    Science.gov (United States)

    Martins, Murillo L.; Ignazzi, Rosanna; Eckert, Juergen; Watts, Benjamin; Kaneno, Ramon; Zambuzzi, Willian F.; Daemen, Luke; Saeki, Margarida J.; Bordallo, Heloisa N.

    2016-03-01

    The most common cancer treatments currently available are radio- and chemo-therapy. These therapies have, however, drawbacks, such as, the reduction in quality of life and the low efficiency of radiotherapy in cases of multiple metastases. To lessen these effects, we have encapsulated an anti-cancer drug into a biocompatible matrix. In-vitro assays indicate that this bio-nanocomposite is able to interact and cause morphological changes in cancer cells. Meanwhile, no alterations were observed in monocytes and fibroblasts, indicating that this system might carry the drug in living organisms with reduced clearance rate and toxicity. X-rays and neutrons were used to investigate the carrier structure, as well as to assess the drug mobility within the bio-nanocomposite. From these unique data we show that partial mobility restriction of active groups of the drug molecule suggests why this carrier design is potentially safer to healthy cells.

  1. Detección de anticuerpos Anti-brucella en focas de Weddell (Leptonychotes weddellii) de Cabo Shirref, Antártica Detection of anti-brucella antibodies in Weddell seals (Leptonychotes weddellii) from cape Shirref, Antarctica

    OpenAIRE

    O. BLANK; P. RETAMAL; P. ABALOS; D. TORRES

    2002-01-01

    Posterior al hallazgo de anticuerpos anti-Brucella en muestras de lobo fino antártico (Arctocephalus gazella), el estudio serológico en Pinnipedia Antárticos se continuó con el fin de determinar la presencia de anticuerpos anti-Brucella en otras especies. Se colectaron muestras de sangre y de fluido extravascular de 12 ejemplares de foca de Weddell (Leptonychotes weddellii) encontrados en el Sitio de Especial Interés Científico (SEIC) Nº 32 y sitio CCAMLR Ecosystem Monitoring Program (CEMP) N...

  2. Evaluación de la presencia de anticuerpos anti-Toxoplasma gondii y anti-Neospora caninum en sueros caninos de la provincia de Buenos Aires mediante las técnicas de inmunofluorescencia indirecta y aglutinación directa

    OpenAIRE

    Gos, María Laura

    2016-01-01

    Objetivos generales: Determinar la presencia de anticuerpos anti-T. gondii y anti-N. caninum en caninos de la provincia de Buenos Aires por la técnica de inmunofluorescencia indirecta y evaluar una prueba de aglutinación comercial para la detección de anticuerpos anti-T. gondii en caninos domésticos. Objetivos específicos: 1. Determinar la presencia de anticuerpos anti-T. gondii y anti-N. caninum en caninos provenientes de la provincia de Buenos Aires en el perí...

  3. Seroprevalence study of anti diphtheria antibodies in two age-groups of Romanian adults.

    Science.gov (United States)

    Dragomirescu, Cristiana Cerasella; Coldea, Ileana-Luminiţa; Ilie, Anamaria; Stănescu, Aurora; Ungureanu, Vasilica; Popa, Mircea Ioan

    2014-01-01

    Diphtheria represents a serious infectious disease with high epidemic potential. It is a vaccine preventable disease (a minimum vaccine coverage of 95% for children of 1 year and 90% in adults could prevent the disease). Diphtheria vaccination is included in the National Immunization Program (NIP). Complete vaccination for children consists in DTaP (diphtheria toxoid, tetanus toxoid and acellular pertussis vaccine) vaccine administration from the age of 2 months until 4 years and dT vaccine (tetanus toxoid and a reduced dose of diphtheria toxoid) at 14 years old. The aim of this paper was to highlight the protection against diphtheria of an age segment of the Romanian adult population (20 to 39 years old) using a seroprevalence study. The Romanian subjects were selected from two age groups: 20-29 years (n = 219) and 30-39 years (n = 229), representative for all counties of Romania. The commercial kit Anti-Diphtheria Toxoid ELISA (IgG) (EUROIMMUN) was used to detect the antibodies of IgG class against diphtheria toxoid in the sera obtained from our subjects. We detected a 56.6% rate of positive sera (> 0.1 IU/ml--protection level) for the 20-29 age group and 31.7% positivity for the 30-39 age group. These data show a low protection level against diphtheria of the Romanian adult population, which decreases with age. The serologic data on preventable vaccine diseases are useful in order to evaluate the success of the immunization programs.

  4. Toxocara canis: Het effect van behandeling met anti-interleukine-5 en anti-interleukine-4 op immunologische en ontstekingsparameters in de longen

    NARCIS (Netherlands)

    Buijs J; Pitstra B; Rouws C; Rees E van; Savelkoul HFJ; LPM; VUA/celbiologie en immunologie; EUR/MF

    1995-01-01

    De toenames van eosinofiele granulocyten en IgE concentraties in Toxocara canis geinfecteerde BALB/c muizen werden geblokkeerd door behandeling met ratte-hybridoma cellen die respectievelijk anti-interleukine-5 (anti-IL-5) en anti-IL-4 produceerden. Doel was het effect te bestuderen van deze

  5. Convection-enhanced delivery of an anti-miR is well-tolerated, preserves anti-miR stability and causes efficient target de-repression

    DEFF Research Database (Denmark)

    Halle, Bo; Marcusson, Eric G; Aaberg-Jessen, Charlotte

    2016-01-01

    target HMGA2 and the inhibition was stable for 24 h. In vivo, anti-miR integrity was preserved in the pumps and no animals showed signs of severe adverse effects attributable to the anti-miR treatment. HMGA2 tumor level was significantly de-repressed in the anti-miR treated animals. The results showed...

  6. Anti-trypanosomal activity of pentacyclic triterpenes isolated from Austroplenckia populnea (Celastraceae Atividade anti-tripanosomicida de triterpenes pentacíclicos isolados de Austroplenckia populnea (Celastraceae

    Directory of Open Access Journals (Sweden)

    Lucienir Pains DUARTE

    2002-04-01

    Full Text Available Four pentacyclic triterpenes isolated from Austroplenckia populnea and four compounds of known anti T. cruzi or anti-malarial activity were tested. Of those triterpenes tested 20alpha-hydroxy-tingenone showed high activity, epikatonic acid was less active, while populnilic and populninic acids were inactive against the trypanosome of the subgenus Schizotrypanum tested. Benzonidazole, nifurtimox, ketoconazole and primaquine presented a remarkable dose-dependent inhibitory effect reaching practically to a total growth inhibition of the parasite at the end of incubation time. The trypanosome tested appear to be a suitable model for preliminary screen for anti T. (S. cruzi compounds.Foram testados quatro triterpenos pentacíclicos isolados de Austroplenckia populnea e quatro compostos de conhecida atividade anti-T. cruzi ou anti-malárica. Dos triterpenos testados 20alfa-hidroxi-tingenona mostrou atividade elevada, ácido epicatônico foi menos ativo, enquanto ácido populnílico e populnínico foram inativos contra o tripanossoma do subgênero Schizotrypanum testado. Benzonidazole, nifurtimox, cetoconazole e primaquina apresentaram efeito inibitório dose-dependente atingindo praticamente a inibição total do crescimento do parasita no final do tempo de incubação. O tripanossoma testado mostrou ser um modelo adequado para uma seleção preliminar de compostos anti. T. (S. cruzi.

  7. Charbonnages de France group. Annual report 99; Groupe Charbonnages de France. Rapport annuel 99

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This 1999 annual report of the French national collieries 'Charbonnages de France' (CDF) presents the turnover and financial data of the group, the situation of coal mining in France, the management of manpower, the rehabilitation of abandoned mine and plant sites, the impact of power market deregulation on the activities of the coal-fired power plants and cogeneration units of the national society of electric and thermal power (SNET) and of the SIDEC company, and the management of the real estate patrimony of the group in mining regions. Some conference texts written by engineers of the group are added at the end of the document and present the competences of CDF in environmental engineering (valorization of coal fly ash, cleansing of polluted sites, phyto-remediation) and development of biomass energy. (J.S.)

  8. Perfil lipídico e uso de anti-TNF-α

    Directory of Open Access Journals (Sweden)

    Antonio Carlos Ferraz Filho

    2013-10-01

    Full Text Available O uso do anti-TNF alfa tem sido associado a várias alterações no perfil lipídico, embora o estudo dessas alterações tenha gerado resultados que ainda são conflitantes. O conhecimento desse fato é de grande importância quando se observa a associação entre doenças reumáticas e aterogenêse acelerada. Esta pesquisa foi feita com o intuito de verificar alterações no perfil lipídico de usuários de anti-TNF-α na população do sul do Brasil e sua associação com tempo de uso, indicações, gênero do paciente e tipo de anti-TNF. Para tanto, analisaram-se os perfis de colesterol total (TC, HDL colesterol (HDLc, LDL colesterol (LDLc, índice aterogênico (IAT e triglicerídeos (TGs de 58 pacientes (42 com artrite reumatoide e 16 com espondiloartrites antes e depois do uso desse medicamento por um tempo mediano de 16,0 meses. Não se observaram alterações nos níveis de CT, HDLc, LDLc e IAT (P = NS. Todavia, houve um aumento significativo nos níveis de TGs (P = 0,03. A diferença mediana dos valores de TGs entre primeira e segunda medidas foi de 16 mg/dL, e esse aumento não estava associado ao gênero do paciente, tempo de uso, indicação de uso ou tipo de anti-TNF-α (P = NS. Concluiu-se que o uso de anti TNF-α está associado com aumento nos valores de TGs.

  9. México, ejemplo de las politicas anti-desarrollo del Consenso de Washington

    Directory of Open Access Journals (Sweden)

    Arturo Guillén

    2012-08-01

    Full Text Available A partir de los avances logrados por el "nuevo-desarrollismo", examina las políticas macroeconómicas implementadas en México en el contexto del Consenso de Washington, la cuales en el caso mexicano fueron institucionalizadas con la firma del Tratado de Libre Comercio de América del Norte (TLCAN. Este tratado consolidó el modelo neoliberal y aherrojó la suerte de la economía mexicana al desempeño de la economía de Estados Unidos. Se analiza la economía mexicana como un caso paradigmático de los efectos anti-crecimiento, de desarticulación de los sistemas productivos y desestabilizadores de las políticas procíclicas inspiradas en el Consenso de Washington. Se concluye que los principales obstáculos para implementar una estrategia alternativa de desarrollo en México, orientada al crecimiento sustentable con equidad, son políticos y residen en la dominación del poder político por una oligarquía financiera rentista que carece de todo idea de proyecto nacional,A partir dos avanços conseguidos pelo "novo-desenvolvimentismo", o artigo examina as políticas macroeconômicas implementadas no México no contexto do Consenso de Washington, as quais, no caso mexicano, foram institucionalizadas com a assinatura do Tratado de Livre Comércio de América do Norte (TLCAN. Este tratado consolidou o modelo neoliberal e agrilhoou a sorte da economia mexicana ao desempenho da economia dos Estados Unidos. No artigo, a economia mexicana analisa-se como um caso paradigmático dos efeitos anticrescimento, de desarticulação dos sistemas produtivos e desestabilizadores das políticas pró-cíclicas inspiradas no Consenso de Washington. Conclui-se que os principais obstáculos para levar à prática uma estratégia alternativa de desenvolvimento no México, orientada ao crescimento sustentável com equidade, são políticos e residem na dominação do poder político por uma oligarquia financeira rentista que carece de qualquer ideia de projeto

  10. Seroprevalence des anticorps anti-HBc chez les donneurs de sang ...

    African Journals Online (AJOL)

    'hépatite virale demeure une priorité pour les centres de qualification des produits sanguins labiles au Togo. Objectif: Déterminer la séroprévalence des anticorps anti-HBc au sein des donneurs de sang en vue d'estimer le niveau de risque ...

  11. Desarrollo a escala de laboratorio de un antiséptico y cicatrizante para uso veterinario incorporando ingredientes naturales

    OpenAIRE

    Fernández Sierra, Laura; Moreno Gómez, Natacha

    2009-01-01

    Con este proyecto se evalúa la posibilidad de desarrollar un antiséptico y cicatrizante para animales a escala de laboratorio, incorporando miel de abejas y Aloe vera como ingredientes activos del producto -- Los ensayos preliminares consistieron en la evaluación de las formulaciones por medio de pruebas de pre-estabilidad entre los diferentes componentes con el extracto etanólico de la miel a temperatura ambiente, y pruebas de estabilidad de cada tratamiento a 4ºC, 50ºC y temperatura ambient...

  12. Evaluación in vitro de la actividad anti Trypanosoma cruzi de aceites esenciales de diez plantas medicinales

    Directory of Open Access Journals (Sweden)

    Juan Rojas

    2010-07-01

    Full Text Available Objetivos: Determinar la actividad anti Trypanosoma cruzi in vitro de los aceites esenciales de 10 plantas medicinales. Además, determinar la actividad citotóxica de los aceites contra células de mamíferos y la actividad modulatoria de los aceites sobre el óxido nítrico. Diseño: Estudio experimental in vitro. Institución: Instituto de Investigaciones Clínicas e Instituto de Medicina Tropical, Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú. Material biológico: Epimastigotes de Trypanosoma cruzi, células Raw 264.7, aceites esenciales de Mentha X piperita L (menta, Rosmarinus officinalis L (romero, Chenopodium ambrosioides L (paico, Eucaliptus globulus Labill (eucalipto, Artemisia absinthium L (ajenjo, Melissa officinalis L (toronjil, Minthostachys setosa Brig (muña, Cimbopogon citratus (hierba luisa, Aloysia triphylla (cedrón y Mentha spicata L (hierba buena. Método: La actividad tripanocida se evaluó contra epimastigotes cultivados en medio LIT, incubados por 48 horas a 37ºC en incubador humidificado con CO2 al 5%. El cristal violeta se utilizó como control positivo. La actividad citotóxica de los productos contra células mamíferas se evaluó en células RAW 264.7 y la actividad modulatoria de los compuestos sobre óxido nítrico también se determinó en los cultivos de células RAW 264.7. Principales medidas de resultados: Porcentaje de inhibición de viabilidad y CI50. Resultados: Los aceites esenciales de Cymbopogon citratus (hierba luisa y Aloysia triphylla (cedrón inhibieron significativamente el crecimiento de la forma epimastigote de T. cruzi, con una CI50 de 63,09 y 96,49 μg/mL, respectivamente. No hubo variaciσn significativa de la concentraciσn de óxido nítrico y tampoco se evidenció citotoxicidad. Conclusiones: Los aceites esenciales de Cymbopogon citratus y Aloysia triphylla mostraron actividad anti-Trypanosoma cruzi in vitro y no fueron citotóxicas para las células mamíferas.

  13. Aglutinina anti-T (Thomsen-Friedenreich na doença de Chagas

    Directory of Open Access Journals (Sweden)

    Marcos Palatnik

    1986-10-01

    Full Text Available Uma amostra de soros de pacientes e controles de uma área endêmica da Doença de Chagas do País foi titulada contra hemácias de grupo O tratadas pela neuraminidase (células OT ativadas e hemacias normais de grupo A e B (sistema ABO. Também foram feitos alguns testes de aglutinação de hemácias de pacientes com cardiomiopatia com as lectinas de amendoim (anti-T + anti-Tk e com anticorpo humano anti-T. O escore médio da aglutinina anti-T dos pacientes foi similar ao do grupo controle. En- tretanto, o escore médio dos indivíduos com a forma cardíaca íoi significantemente maior que o dos pacientes assintomáticos e também maior que o do grupo controle. A comparação entre indivíduos com sorologia diagnóstica positiva versus negativa foi não significante. Nem a sorologia para Chagas nem as variáveis raça, sexo, idade, idade ao quadrado, in-fecção intestinal parasitária, teor de proteínas do soro, volume globular eritrocitário (hema-tócrito, grau de palidez da mucosa bucal, cardíomiopatia e os termos de interação sexo x idade, sexo x idade ao quadrado, estão associados significativamente com o logaritmo do título ou com o logaritmo do escore de aglutinação. Os escores de aglutinação das aglutininas anti-A e anti-B do sistema de grupo sangüíneo ABO estão dentro da faixa de variação normal. As hemácias de pacientes com a forma cardíaca não são aglutinadas nem pelas lectinas de amendoim (antiT + anti-Tk e da soja (anti-T nem pela aglutinina anti-T de origem humana. A prova de Coombs direta foi negativa em todos os pacientes, demonstrando a aparente ausência de imunoglobulinas IgG e IgM na superfície eritrocitária. O fato de que o aumento dos níveis de anti-T só foi detectado em uma das formas clínicas da doença em pacientes da mesma área endêmica constitui um argumento contra a possibilidade de que a variação observada seja produzida por uma infecção concomitante.

  14. Anuncian primera produccion controlada de anti-atomos frios

    CERN Multimedia

    2002-01-01

    "Un equipo internacional que trabaja con el desacelerador de antiprotones del CERN, en Ginebra, ha conseguido la primera produccion controlada de miles de atomos de hidrogeno de baja energia, lo que facilitara en el futuro los analisis de precision en varias disciplinas cientificas" (1 page).

  15. A Policy of Futility: Eamon de Valera’s Anti-Partition Campaign, 1948-1951

    OpenAIRE

    Kelly, Stephen

    2012-01-01

    This article offers the first comprehensive analysis of the world-wide anti-partition campaign undertaken by Eamon de Valera from 1948 to 1951. First, it examines the propaganda de Valera employed in the United States of America, Australia, New Zealand and Great Britain in support of ending the partition of Ireland. Second, it analyses de Valera’s involvement with the anti-partition campaign in Ireland. The central argument is that de Valera’s use of propaganda abroad and in Ireland to make a...

  16. Anticuerpo anti-Dectin-1 humano, hibridoma productor de dicho anticuerpo y sus aplicaciones

    OpenAIRE

    Llorente Gómez, María de las Mercedes; Fernández Ruíz, Elena; Galán Díez, Marta; Kremer, Leonor; Casasnovas, José María

    2008-01-01

    Anticuerpo anti-Dectin-1 humano, hibridoma productor de dicho anticuerpo y sus aplicaciones. La presente invención consiste en el hibridoma MGD3 y el anticuerpo monocional producido por él (denominado también MGD3), que reconoce de forma especifica al receptor de membrana Decti-1 humano. El anticuerpo MGD3 es capaz de inhibir la unión de Dectin-1 a su ligando natural, los -glucanos que son componentes de la pared de los hongos. Además, bloquea específicamente la un...

  17. Ação anti-úlcera e cicatrizante de algumas plantas brasileiras

    Directory of Open Access Journals (Sweden)

    Elfriede Marianne Bacchi

    Full Text Available Apresentamos uma revisão de algumas plantas brasileiras, existentes na região de São Paulo, conhecida por sua ação anti-úlcera e cicatrizante. As espécies citadas neste trabalho são: sucupira, jucá,erva de bugre, taiuiá, cipó-chumbo,coipó-caboclo, carobinha, saião, cordão de frade, aroeira e estoraque do campo.

  18. Quantum algebras as quantizations of dual Poisson–Lie groups

    International Nuclear Information System (INIS)

    Ballesteros, Ángel; Musso, Fabio

    2013-01-01

    A systematic computational approach for the explicit construction of any quantum Hopf algebra (U z (g), Δ z ) starting from the Lie bialgebra (g, δ) that gives the first-order deformation of the coproduct map Δ z is presented. The procedure is based on the well-known ‘quantum duality principle’, namely the fact that any quantum algebra can be viewed as the quantization of the unique Poisson–Lie structure (G*, Λ g ) on the dual group G*, which is obtained by exponentiating the Lie algebra g* defined by the dual map δ*. From this perspective, the coproduct for U z (g) is just the pull-back of the group law for G*, and the Poisson analogues of the quantum commutation rules for U z (g) are given by the unique Poisson–Lie structure Λ g on G* whose linearization is the Poisson analogue of the initial Lie algebra g. This approach is shown to be a very useful technical tool in order to solve the Lie bialgebra quantization problem explicitly since, once a Lie bialgebra (g, δ) is given, the full dual Poisson–Lie group (G*, Λ) can be obtained either by applying standard Poisson–Lie group techniques or by implementing the algorithm presented here with the aid of symbolic manipulation programs. As a consequence, the quantization of (G*, Λ) will give rise to the full U z (g) quantum algebra, provided that ordering problems are appropriately fixed through the choice of certain local coordinates on G* whose coproduct fulfils a precise ‘quantum symmetry’ property. The applicability of this approach is explicitly demonstrated by reviewing the construction of several instances of quantum deformations of physically relevant Lie algebras such as sl(2,R), the (2+1) anti-de Sitter algebra so(2, 2) and the Poincaré algebra in (3+1) dimensions. (paper)

  19. manifestação de síndrome anti-sintetase

    Directory of Open Access Journals (Sweden)

    Mário Pires

    2014-03-01

    Apresentamos o caso de um homem com diagnóstico efectuado há 13 anos, no contexto de internamento por uma “pneumonia”, com queixas de dispneia para esforços e cansaço fácil com 3 meses de evolução. Durante o internamento é identificada uma doença pulmonar intersticial e, posteriormente surge um quadro de mialgias com elevação marcada das enzimas musculares. A electromiografia mostrou um padrão sugestivo de miopatia e identificou-se anticorpos anti-Jo-1, estabelecendo-se o diagnóstico de síndrome anti-sintetase. Sob terapêutica imunossupressora desde então, mantém seguimento em consulta externa, encontrando-se clinicamente bem.

  20. Anti-high Mobility Group Box 1 Antibody Ameliorates Albuminuria in MRL/lpr Lupus-Prone Mice

    Directory of Open Access Journals (Sweden)

    Haruki Watanabe

    2017-09-01

    Full Text Available We evaluated the efficacy of a neutralizing anti-high mobility group box 1 (HMGB1 monoclonal antibody in MRL/lpr lupus-prone mice. The anti-HMGB1 monoclonal antibody (5 mg/kg weight or class-matched control immunoglobulin G2a (IgG2a was administered intravenously twice a week for 4–15 weeks. Urine albumin was monitored, and histological evaluation of the kidneys was conducted at 16 weeks. Lymphadenopathies were evaluated by 1-(2′-deoxy-2′-[18F]fluoro-β-D-arabinofuranosylcytosine ([18F]FAC positron emission tomography/computed tomography (PET/CT at 12 weeks. Following 4-week treatment, [18F]FAC-PET/CT showed similar accumulation in cervical and axillary lymph nodes at 12 weeks of age. However, anti-HMGB1 monoclonal antibody sufficiently inhibited the increase in albuminuria compared to an isotype control following 15-week treatment. Complement deposition was also improved; however, there were no significant differences in IgG deposition and renal pathological scores between the two groups. Anti-double-stranded DNA (dsDNA antibody titers and cytokine and chemokine levels were also unaltered. Although there were no significant differences in glomerular macrophage infiltration, neutrophil infiltration was significantly decreased by the anti-HMGB1 monoclonal antibody. Antagonizing HMGB1 treatment suppressed HMGB1 translocation from nuclei in the kidney and suppressed neutrophil extracellular traps. The anti-HMGB1 monoclonal antibody demonstrated therapeutic potential against albuminuria in lupus nephritis by inhibiting neutrophil recruitment and neutrophil extracellular traps.

  1. Acción de los antisépticos sobre la piel

    OpenAIRE

    Oviedo Arévalo, Juan José; Obiols, Cecilia Isabel; Friso, Nélida Ester; Escudero Giachella, Ezequiel; Tomas, Leandro Juan; González, Anabel Mariela; Arce, Giselle; Carballeira, Valentina; Cornes, Damián; Ricciardi, Luciana; Jones, Lizzie; Spada, Vanesa; Mayocchi, Martín

    2017-01-01

    Los antisépticos son drogas de acción inespecífica, de acción local y uso frecuente. Pasteur y Koch sentaron las bases de la lucha contra los microorganismos por Lister, quien preconizo la limpieza, la antisepsia, la desinfección y la esterilización. Se emplearon para este estudio cloruro de benzalconio, yodo povidona, alcohol 70 %, comparando su acción como un detergente (jabón de tocador). El estudio se realizo sobre un total de 375 alumnos distribuidos en 15 grupos; se les proveyó placas c...

  2. jovem portador de deficiência mental com conduta anti-social

    OpenAIRE

    Moura, Sérgio Adriano Fonseca

    2009-01-01

    Dissertação de Mestrado apresentada à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Psicologia, especialização em Psicologia Clínica e da Saúde. O presente estudo de caso propõe-se a estudar o eventual diagnóstico de Deficiência Mental (Atraso Mental) e a Perturbação da Personalidade Anti-Social num jovem de 18 anos, que se encontra sob a custodia da Segurança Social e reside num Lar de Acolhimento. O estudo tem dois grandes objectivos: ...

  3. Detección de anticuerpos anti-Leishmania (Trypanosomatidae en poblaciones caninas del departamento de Sucre, Colombia

    Directory of Open Access Journals (Sweden)

    Luís Enrique Paternina Tuirán

    2016-01-01

    Full Text Available El objetivo de la investigación fue determinar la prevalencia de anticuerpos anti-Leishmania en perros del departamento de Sucre, Colombia. Se analizaron 122 perros del área rural de los municipios de Ovejas, Sampués y Sincelejo, mediante la técnica de inmunofluorescencia indirecta (IFI. Anticuerpos anti-Leishmania fueron detectados en el 69,6 % (IC95 % = 61,1 – 78,2 de la población canina estudiada. En el municipio de Sincelejo la seropositividad fue del 72 % (IC95 % = 61,1 – 82,8, en el municipio de Sampués del 68,4 % (IC95 % = 52,3 – 84,5 y en el municipio de Ovejas del 55,5 % (IC95 % = 21,2 – 86,3. Los animales seropositivos fueron principalmente caninos jóvenes y adultos. El 17,6 % de los perros seropositivos mostró signos clínicos compatibles con leishmaniasis canina, entre los cuales la onicogrifosis, alopecia y caquexia fueron los más comunes. La alta frecuencia de caninos con anticuerpos a Leishmania detectada en el presente estudio, pone de manifiesto la hiperendemicidad de la leishmaniasis canina en esta zona del país, así como el alto riesgo de brotes epidémicos de la enfermedad.

  4. Reactividad inmunoquímica de sueros anti- Caiman yacare y Caiman latirostris frente a sueros de diferentes especies

    Directory of Open Access Journals (Sweden)

    de Roodt, Adolfo Rafael

    2010-06-01

    Full Text Available Se estudió la reactividad inmunoquímica entre los sueros de distintas especies de reptiles frente a sueros hiperinmunes experimentales anti-suero de Caiman yacare y anti-suero de Caiman latirostris. Los sueros que se probaron fueron los homólogos de Caiman yacare, Caiman latirostris y los heterólogos de Alligator missisipiensis, Tupinambis merinae, Tupinambis rufescens, Chelonoidis chilensis, Clelia rustica, Waglerophis merremii, Lystrophys dorbignyi, Phyton molurus, Boa constrictor occidentalis, Eunectes notaeus, Crotalus durissus terrificus, Bothrops alternatus, Bothrops diporus, Bothrops jararaca, Bothrops jararacussu, Bothrops moojeni, Pitangus sulphuratus y Gallus gallus. La reactividad inmunoquímica se determinó mediante las técnicas de doble inmunodifusión y ELISA, mostrándose importante entre los sueros de los crocodrílidos y baja entre estos y los de las otras especies de reptiles estudiadas. Se observó mayor reactividad entre los antisueros anti-Caiman respecto a los sueros de Caiman latirostris y Caiman yacare que frente al suero de Alligator missisipiensis. Además, se encontró una fuerte reactividad entre ambos sueros anti-Caiman y el de Gallus gallus poniendo en evidencia la fuerte reactividad entre los sueros de arcosaurios. In order to study the immunochemical reactivity among sera from different species of reptiles regarding sera from Caiman, the immunoreactivity of sera from reptiles against antisera to Caiman yacare or anti-Caiman latirostris sera was studied. These hiperimmune sera were tested against sera from Alligator missisipiensis, Tupinambis merinae, Tupinambis rufescens, Chelonoidis chilensis, Clelia rustica, Waglerophis merremii, Lystrophys dorbignyi, Phyton molurus, Boa constrictor occidentalis, Eunectes notaeus, Crotalus durissus terrificus, Bothrops alternatus, Bothrops neuwiedii, Bothrops jararaca, Bothrops jararacussu, Bothrops moojeni, Pitangus sulphuratus and Gallus gallus. The immunochemical

  5. Charged scalar perturbations on charged black holes in de Rham-Gabadadze-Tolley massive gravity

    Science.gov (United States)

    Burikham, Piyabut; Ponglertsakul, Supakchai; Tannukij, Lunchakorn

    2017-12-01

    We explore the quasistationary profile of a massive charged scalar field in a class of charged black holes in de Rham-Gabadadze-Tolley (dRGT) massive gravity. We discuss how the linear term in the metric, which is a unique character of the dRGT massive gravity, affects the structure of the spacetime. Numerical calculations of the quasinormal modes are performed for a charged scalar field in the dRGT black hole background. For an asymptotically de Sitter (dS) black hole, an improved asymptotic iteration method is used to obtain the associated quasinormal frequencies. The unstable modes are found for the ℓ=0 case, and their corresponding real parts satisfy the superradiant condition. For ℓ=2 , the results show that all the de Sitter black holes considered here are stable against a small perturbation. For an asymptotically dRGT anti-de Sitter (AdS) black hole, unstable modes are found with the frequency satisfying the superradiant condition. Effects of massive-gravity parameters are discussed. Analytic calculation reveals the unique diffusive nature of quasinormal modes in the massive-gravity model with the linear term. Numerical results confirm the existence of the characteristic diffusive modes in both the dS and AdS cases.

  6. Determinación de anticuerpos anti-β2glicoproteína I en pacientes con síndrome antifosfolípido Anti- β2 glycoprotein antibodies in patients with antiphospholipid syndrome

    Directory of Open Access Journals (Sweden)

    Oscar Uribe Uribe

    2004-09-01

    Full Text Available EL objetivo de este estudio fue comparar la presencia de anticuerpos anti-β2glicoproteína I (anti- β2GPI con las pruebas convencionales de laboratorio de anticuerpos anticardiolipina (aCL y anticoagulante lúpico, y con las manifestaciones clínicas del síndrome antifosfolípido (SAF. Se incluyeron en el estudio 80 mujeres con SAF; 35 de ellas de la consulta de Reumatología y las otras 45 con historia de aborto recurrente espontáneo (ARE; 5 mujeres de la consulta de Reumatología sin SAF, 27 mujeres con ARE, sin SAF y un grupo control de 20 mujeres sanas en edad reproductiva. Se investigaron la presencia de anticuerpos IgG e IgM anticardiolipina (aCL e IgG anti- β2GPI por la técnica de ELISA, y el anticoagulante lúpico por la determinación del tiempo parcial de tromboplastina activado. Adicionalmente, se registraron las manifestaciones clínicas asociadas al SAF. De las pacientes con SAF, 25.7% del grupo de Reumatología (9/35 y 4.4% de las pacientes con ARE (2/45 fueron positivas para anticuerpos anti-β2GPI, mientras que ninguna de las mujeres sin SAF, ni de las mujeres del grupo control, fue positiva. La asociación entre la presencia de anti- β2GPI y los anticuerpos IgG e IgM aCL mostró una diferencia significativa en los títulos de 3+ (altamente positivos en contraste con los individuos negativos para anti- β2GPI. La positividad del anticoagulante lúpico también se correlacionó con la presencia de anticuerpos anti- β2GPI. No hubo diferencia significativa entre las diversas manifestaciones clínicas del SAF y la presencia de dichos anticuerpos. En conclusión, la determinación de anticuerpos anti- β2GPI tiene una alta especificidad en pacientes con SAF pero no se asoció con ninguna manifestación clínica en particular. The objective of this study was to compare the presence of anti-β2glycoprotein (anti- β2GPI antibodies with the conventional laboratory tests of anticardiolipin antibodies (aCL and lupus anticoagulant

  7. ELISA cualitativo de IgA anti-Lipopolisacárido de Vibrio cholerae en saliva de humanos

    Directory of Open Access Journals (Sweden)

    Judith Mónica del Campo

    2002-03-01

    Full Text Available Se estandarizó un ELISA para detectar el principal antígeno inductor de protección de Vibrio cholerae en saliva IgA contra el lipopolisacárido (LPS. El estudio se llevó a cabo en voluntarios que fueron inoculados por vía oral con dosis de 0, 107, 108, 109 unidades formadoras de colonias (ufc del candidato vacunal El Tor Ogawa, cepa 638. Las muestras de saliva fueron tomadas de forma seriada, a los 0, 7, 8, 9, 10 y 14 días postinoculación. Se consideró seroconversión si las densidades ópticas eran superiores al nivel de corte y si los incrementos después de inmunizar duplicaban los valores antes de la inmunización. Los resultados, al ser comparados con los grupos experimentales, condición individuos inoculados y los placebos, demostraron que la técnica tiene una sensibilidad del 93,3%, una especificidad del 96,0%, un valor predictivo positivo de 98,2% y negativo de 85,7%, y una eficiencia del 94,1%. Se demostró la presencia de IgA anti LPS en saliva de los individuos inoculados con el candidato vacunal, con una mayor concentración de anticuerpos con el inóculo de (109 ufc y se obtuvo la máxima positividad a los nueve días.

  8. Gauge Fields as Composite Boundary Excitations

    CERN Document Server

    Ferrara, Sergio; Ferrara, Sergio; Fronsdal, Christian

    1998-01-01

    We investigate representations of the conformal group that describe "massless" particles in the interior and at the boundary of anti-de Sitter space. It turns out that massless gauge excitations in anti-de Sitter are gauge "current" operators at the boundary. Conversely, massless excitations at the boundary are topological singletons in the interior. These representations lie at the threshold of two "unitary bounds" that apply to any conformally invariant field theory. Gravity and Yang-Mills gauge symmetry in anti-De Sitter is translated to global translational symmetry and continuous R-symmetry of the boundary superconformal field theory.

  9. Busca de sensação e condutas anti-sociais e delitivas em jovens

    Directory of Open Access Journals (Sweden)

    Nilton Soares Formiga

    Full Text Available O fenômeno das condutas juvenis tem sido alvo de interesse na ciência social e humana, principalmente aquelas que conduzem à delinqüência. Apesar de inúmeras variáveis conseguirem explicá-lo, o construto busca de sensações vem contribuindo muito para isso, pois ele enfatiza as diferenças individuais. A partir da perspectiva personalística, aponta a avaliação do grau com que os jovens pretendem viver experiências em correr riscos e sua predisposição a sensações de novidades e intensidades. 504 jovens, entre 11 e 20 anos, responderam o questionário de condutas anti-sociais e delitivas e de busca de sensação, de Arnett. Observou-se que a busca de intensidade e de novidades se relacionaram diretamente às condutas anti-sociais e delitivas. Esses resultados permitem supor que as variáveis personalísticas ainda têm bastante contribuição quando se pretende explicar a conduta juvenil delinqüente a partir da orientação de atitudes frente à excitação e ao investimento de atividades permeadoras de risco.

  10. Busca de sensação e condutas anti-sociaise delitivas em jovens

    Directory of Open Access Journals (Sweden)

    Nilton Soares Formiga

    Full Text Available O fenômeno das condutas juvenis tem sido alvo de interesse na ciência social e humana, principalmente aquelas que conduzem à delinqüência. Apesar de inúmeras variáveis conseguirem explicá-lo, o construto busca de sensações vem contribuindo muito para isso, pois ele enfatiza as diferenças individuais. A partir da perspectiva personalística, aponta a avaliação do grau com que os jovens pretendem viver experiências em correr riscos e sua predisposição a sensações de novidades e intensidades. 504 jovens, entre 11 e 20 anos, responderam o questionário de condutas anti-sociais e delitivas e de busca de sensação, de Arnett. Observou-se que a busca de intensidade e de novidades se relacionaram diretamente às condutas anti-sociais e delitivas. Esses resultados permitem supor que as variáveis personalísticas ainda têm bastante contribuição quando se pretende explicar a conduta juvenil delinqüente a partir da orientação de atitudes frente à excitação e ao investimento de atividades permeadoras de risco.

  11. Experiencia clínica con el uso de los anticuerpos anti-CdtB y anti-vinculina en pacientes con diarrea en México

    OpenAIRE

    Schmulson, M.; Balbuena, R.; Corona de Law, C.

    2016-01-01

    Introducción: Se ha validado el uso de los anticuerpos anti-CdtB/anti-vinculina como biomarcadores para discriminar el SII-D de la EII, más no hay experiencia con ellos en Latinoamérica. Materiales y métodos: Se analizaron pacientes que consultaron a una clínica de TGIF/motilidad en los últimos 7 meses por diarrea con dolor/distensión abdominal, y a quienes se les solicitó estos anticuerpos. Los pacientes fueron diagnosticados mediante los criterios de Roma III o con trastornos orgánicos. ...

  12. Prevalencia de anticuerpos anti-Chlamydia trachomatis y anti-Neisseria gonorrhoeae en grupos de individuos de la población mexicana Prevalence of antibodies against Chlamydia trachomatis and Neisseria gonorrhoeae in Mexican populations

    Directory of Open Access Journals (Sweden)

    María del Carmen Cravioto

    2003-01-01

    (NG infection in groups of individuals at different risks of sexually transmitted infections (STI. MATERIAL AND METHODS: Between January 1992 and December 1993, a cross-sectional multicentric study was carried out at the Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (National Institute of Medical Sciences and Nutrition "Salvador Zubirán" in Mexico City. The study population consisted of 945 reproductive age subjects (585 females and 360 males. Low and high risk groups were classified according to their risk for STI. High risk groups included infertile women with tubal damage, women with a history of ectopic pregnancy or abortion, infertile men, HIV/AIDS patients, homo- or bisexual men, and female commercial sex workers. Low risk groups included primigravidae, fertile men, and infertile women with no tubal damage. Serum anti-NG and anti-CT IgG and IgA were determined, in duplicate by immune-enzymatic assay, using as antigens NG pili and the L1 fraction of CT. Descriptive analysis is presented as percentages. RESULTS: NG prevalence in females was 13.7% by IgG and 14.3% by IgA. CT prevalence was 11.4% by IgG and 4.4% by IgA. In males, NG prevalences were 3.3% and 13.3% by IgG and IgA, respectively; CT prevalences were 7.2% and 5.5%, respectively. In commercial sex workers, NG prevalences were 31.2% by IgG and 28.4% by IgA, and CT 25.0% and 5.7% by IgG and IgA, respectively. In women with infertility due to tubal damage the prevalences of NG were 5.6% and 9.8%, respectively, and those of CT were 8.4% and 1.4%, respectively. In 110 young primigravid NG prevalences were 4.5% and 10.0%, respectively, and CT 3.6% and 9.1%. CONCLUSIONS: These data confirm the high prevalence of Neisseria gonorrhoeae and Chlamydia trachomatis in female commercial sex workers and homo- or bisexual men, but not in other high-risk groups like infertile women or women with a history of ectopic pregnancy or abortion.

  13. ANTI-CIUDAD COMO INFRAESTRUCTURA. EL SISTEMA LINEAL CONTINUO DE OSKAR HANSEN / Anti-city as infrastructure. Oskar Hansen’s Linear Continuous System

    Directory of Open Access Journals (Sweden)

    Marta López-Marcos

    2015-11-01

    Full Text Available RESUMEN Durante las décadas de la Guerra Fría, el continente europeo se encuentra sumido en un complejo proceso de transformación, reconstrucción y planteamiento de nuevos proyectos políticos y territoriales. Esta situación es especialmente convulsa en la franja centroeuropea, donde en estados como Hungría, Polonia o la antigua Yugoslavia se daban profundos debates acerca de su identidad y su organización geopolítica. El progresivo aperturismo hacia los países occidentales, junto a la necesidad de modernizar en profundidad los sistemas e infraestructuras estatales, sirvieron como catalizadores para la proliferación de grandes proyectos territoriales y urbanos con el fin no solo de mejorar la calidad de vida de los habitantes, sino también de reforzar la posición de dichos estados en el continente y el resto del mundo. Este texto se centra en el caso de la República Popular de Polonia, donde estas cuestiones se trataron con gran profusión desde diversas ramas. Concretamente, la propuesta del arquitecto Oskar Hansen para un Sistema Lineal Continuo aúna la visión socialista del estado como agente productor del espacio con la participación individual dentro del colectivo –siguiendo su Teoría de la Forma Abierta y sus conexiones con el Team X- sobre un soporte arquitectónico : un modelo deanti-ciudad” que abriría cuestiones que todavía hoy permanecen vigentes. SUMMARY During the decades of the Cold War, Europe was plunged into a complex process of transformation, reconstruction and the emergence of new political and territorial projects. This situation caused particular upheaval in the central European strip, where states such as Hungary, Poland and the former Yugoslavia were struck by a profound quandary as to their identity and their geopolitical organisation. As they gradually opened up towards western countries and understood the need to drastically modernise the states’ systems and infrastructures, this triggered

  14. Toxocara seroprevalence in children from a subtropical city in Argentina Prevalencia de anticuerpos anti Toxocara en niños de una ciudad subtropical de Argentina

    Directory of Open Access Journals (Sweden)

    José Mario ALONSO

    2000-08-01

    Full Text Available Most studies from Argentina have focused on toxocariasis as an environmental problem of big cities, and there are no available data about children infection from small or middle-sized cities. In order to assess the prevalence of anti-Toxocara antibodies in infantile population, 206 children from Resistencia, of both sexes, aged 1-14 years old were studied by Elisa testing with E/S T. canis L2 antigens. Hematological parameters and immunoglobulin levels were determined; five days' stool samples were studied and epidemiological data were obtained by means of a questionnaire to parents. Results showed that 73% of the children had one or more dogs living at home, 57% reported geophagia and 37.9% were positive for Toxocara serology, but there was no significant difference in prevalence neither for boys and girls, nor concerning age. An increased risk of infection was observed in age groups 5-6 and 7-8 for boys, and in age groups 3-4 and 5-6 for girls.La mayoría de los estudios realizados en Argentina, han enfocado a la Toxocariosis como un problema medioambiental propio de las grandes ciudades y no existen datos acerca de esta infección entre los niños de ciudades medianas o pequeñas. A fin de determinar la prevalencia de anticuerpos anti-Toxocara en la población infantil de la ciudad de Resistencia, se estudiaron 206 niños de ambos sexos, con edades comprendidas entre los 1-14 años, mediante el test de Elisa, empleando antígenos E/S de larva L2 de Toxocara canis. También se evaluaron los niveles de inmunoglobulinas séricas y los parámetros hematológicos; se efectuaron análisis coproparasitológico seriados en heces de 5 días y se recolectó información epidemiológica mediante cuestionario a los padres. Los resultados obtenidos señalan que el 73% de los niños tenían uno o mas perros viviendo en la casa, que el 57% tenían antecedentes de geofagia y que el 37.9% tenían serología positiva para Toxocara, aunque no hubo diferencias

  15. Alternatives to Anti-Personnel Landmines (Solutions de remplacement aux mines antipersonnel)

    Science.gov (United States)

    2003-05-01

    remplacement ont un prix : elles sont plus pesantes sur le plan logistique et impliquent des risques opérationnels pour les forces de l’OTAN. En...très importante, de l’interopérabilité dans le transfert de secteurs qui ont été minés par un pays non-signataire de la Convention d’Ottawa. Le...SEINE CEDEX, FRANCE RTO TECHNICAL REPORT 40(I) Alternatives to Anti-Personnel Landmines (Solutions de remplacement aux mines antipersonnel) Military

  16. Responsabilite societale des entreprises et groupes de societes ...

    African Journals Online (AJOL)

    Mots clés: Responsabilité Sociétale des Groupes de Sociétés ; développement durable ; protection. English Title: Social responsibility of companies and groups of companies. English Abstract. The social responsibility (CSR) corporate social is the contribution of business to sustainable development issues. The approach is ...

  17. Cultura no grupo de brinquedo Culture in the play group

    Directory of Open Access Journals (Sweden)

    Ana Maria Almeida Carvalho

    2002-01-01

    Full Text Available Discute-se o conceito de cultura em relação à microcultura do grupo de brinquedo. Concebe-se a criança como agente de criação e transmissão de cultura e o grupo de brinquedo como espaço de informação onde esses processos ocorrem. Essa concepção baseia-se no reconhecimento da espécie humana como biologicamente sócio-cultural e na pressuposição de adaptações precoces para essa especificidade. Episódios de atividade lúdica livre de crianças de 10 a 60 meses são analisados para detectar a ocorrência de criação, elaboração e transmissão de conteúdos culturais na interação criança-criança, ilustrando: (1 recuperação da cultura do ambiente social imediato e exploração de novas possibilidades de uso desses recursos; (2 criação de rituais lúdicos novos que podem tornar-se parte da microcultura do grupo; (3 aculturação, ou seja, assimilação de aspectos da microcultura do grupo. Os dados são interpretados como evidências da pré-adaptação humana para a vida sócio-cultural.This paper discusses the concept of culture in the context of playgroup microcultures. The child is viewed as an agent of culture creation and innovation, and the play group as a space of information where these processes occur. This view is based on the recognition of human species as biologically socio-cultural and on the assumption of precocious adaptations for this specificity. Episodes of free play activity among 10 to 60 month old children are analysed to detect the occurrence of creation, elaboration and transmission of cultural contents in child-child interactions, illustrating: (1 retrieval of the immediate social environment's culture and exploration of new possibilities of using these resources; (2 creation of new ludic rituals which can become part of the group's microculture; (3 aculturation, that is, assimilation of aspects of the group's microculture. Data are interpreted as evidences of the human pre-adaptation to a socio

  18. New cases of irregular blood group antibodies other than anti-D in pregnancy. Frequency and clinical significance.

    Science.gov (United States)

    Kornstad, L

    1983-01-01

    The frequency of irregular blood group antibodies detected for the first time in pregnant women during the period 1975-80 has been examined. Whereas Rh(D)-negative gravidae in Norway are examined immuno-hematologically three times during pregnancy, Rh(D)-positive women are tested once only, usually early in pregnancy. Nevertheless, about one-third of the new cases of immunization within the Rh system were found in the Rh-positive women. In the latter, anti-E and anti-c were the Rh antibodies most frequently encountered. Among other irregular antibodies which can cause hemolytic disease of the newborn (HDN), those of the Kell and Duffy systems are the ones second in frequency and clinical significance to the Rh antibodies. In the present series about 40% of the new cases of immunization within the Rh, Kell and Duffy systems were found in Rh-positive women. This proportion would undoubtedly have been greater if also the Rh-positive women had been retested for the presence of irregular blood group antibodies towards the end of the gestation. Such a retesting of Rh-positive gravidae is desirable both for a better prediction and early diagnosis of HDN and to facilitate the procurement of compatible blood if the woman should need an emergency blood transfusion.

  19. O uso de drogas anti-reumáticas na gravidez Use of anti-rheumatic drugs during pregnancy

    Directory of Open Access Journals (Sweden)

    Roger A. Levy

    2005-06-01

    Full Text Available A prescrição de drogas anti-reumáticas em pacientes férteis deve ter em conta o conhecimento atual sobre os efeitos na concepção, gestação e lactação. Um aconselhamento que levasse em consideração os riscos e benefícios do planejamento da gravidez, quando possível, seria o ideal. Com a incorporação de novas substâncias e o aparecimento constante de novos dados na literatura, esse assunto deve ser continuamente atualizado. O estagiamento de acordo com o fator de risco estabelecido pelo FDA é algumas vezes contraditório em relação a nossa prática, em parte porque os estudos em modelos animais podem não ser diretamente aplicáveis a humanos. A terapia com agentes modificadores da resposta biológica é aparentemente segura durante a gestação, considerando-se que tais agentes sejam compostos por moléculas grandes, incapazes de atravessar a placenta. Antiinflamatórios não-esteroidais (incluindo os inibidores específicos de COX-2 podem prejudicar a implantação do óvulo, mas o seu uso é possível no caso da gestação estar em curso, devendo ser evitados após 32 semanas do início da gravidez, quando estão relacionados com complicações fetais. Os inibidores específicos de COX-2 devem ser evitados pelo risco de malformação renal. Aspirina em baixa dose pode ser usada seguramente, quando indicada durante a gravidez. Há preferência pelas heparinas de baixo peso molecular, desde que a não fracionada apresente maior risco de induzir trombocitopenia e sangramento. A hidroxicloroquina é usada e de fato recomendada em gestantes com lúpus, com benefícios para a paciente e sem risco fetal. Varfarina é teratogênica se usada da 6ª a 9ª semana de gestação, mas pode ser usada durante o segundo e terceiro trimestres até a 34ª semana, quando deve ser interrompida com o intuito de evitar sangramento fetal. A imunoglobulina endovenosa é recomendada em casos difíceis de síndrome do anticorpo antifosfolipídeo e vem

  20. Características dos doadores de córneas do Banco de Olhos de Cascavel: impacto do exame anti-HBc para hepatite B

    Directory of Open Access Journals (Sweden)

    Cesar Nobuo Shiratori

    2011-02-01

    Full Text Available OBJETIVOS: Traçar o perfil dos doadores de tecidos oculares humanos na região de atuação do Banco de Olhos de Cascavel - Paraná (PR e verificar o impacto da positividade da sorologia positiva para hepatite B (anti-HBc no descartes dos tecidos oculares. MÉTODOS: Estudo do tipo transversal de dados do Banco de Olhos de Cascavel do período de março de 2006 a abril de 2007. Informações como idade, sexo, causa de óbito, tempo entre óbito e enucleação e resultados sorológicos de doadores foram coletadas. Dados foram agrupados para caracterização da população de estudo e distribuídos segundo positividade da sorologia para hepatite B (anti-HBc. RESULTADOS: A média de idade dos doadores foi de 54,2 ± 20,6 anos e a maioria era do sexo masculino (64,7%. Tempo médio entre óbito e enucleação foi de 3,8 ± 2,4 horas, a principal causa de óbito foram doenças cardiovasculares (34,5%. Positividade para os marcadores anti-HBc e HBsAg foi de 47,4% e 1,5%, respectivamente, sendo os exames sorológicos para hepatite B a maior causa de descarte dos tecidos oculares doados. Doadores com sorologia positiva para anti-HBc apresentaram maior média de idade comparados com doadores com sorologia negativa (p<0,001. Somente 0,8% das doações apresentaram sorologia positiva para hepatite C. Não houve doações com sorologia para HIV positiva no período do estudo. CONCLUSÕES: Implementação do Banco de Olhos de Cascavel aumentou significativamente a disponibilização de córneas para transplante no Estado do Paraná. A principal contraindicação para disponibilização de tecidos oculares foi a positividade na sorologia para anti-HBc. Estudos de biosegurança devem ser realizados a fim de investigar o potencial de transmissão da hepatite B de doadores positivos para esse marcador. A inclusão desses doadores como doações efetivas acarretaria maior disponibilização de tecidos para transplantes.

  1. Arrhythmogenicity of Anti-Ro/SSA Antibodies in Patients With Torsades de Pointes.

    Science.gov (United States)

    Lazzerini, Pietro Enea; Yue, Yuankun; Srivastava, Ujala; Fabris, Frank; Capecchi, Pier Leopoldo; Bertolozzi, Iacopo; Bacarelli, Maria Romana; Morozzi, Gabriella; Acampa, Maurizio; Natale, Mariarita; El-Sherif, Nabil; Galeazzi, Mauro; Laghi-Pasini, Franco; Boutjdir, Mohamed

    2016-04-01

    In patients with autoimmune disease, anti-Ro/SSA antibodies (anti-Ro/SSA) are responsible for a novel autoimmune-associated long-QT syndrome by targeting the hERG potassium channel and inhibiting the related current (IKr). Because anti-Ro/SSA are also present in a significant proportion of healthy subjects and may be associated with torsades de pointes (TdP) arrhythmia, we tested the hypothesis that anti-Ro/SSA may represent a silent risk factor in patients developing TdP. Twenty-five consecutive patients who experienced TdP were prospectively collected independent of ongoing therapies and concomitant diseases. Anti-Ro/SSA were detected by fluoroenzyme immunoassay, immuno-Western blotting, and line-blot immunoassay. Purified IgGs from anti-Ro/SSA-positive and anti-Ro/SSA-negative patients were tested on IKr using HEK293 cells stably expressing the hERG channel. As expected, in TdP patients, many known corrected QT interval-prolonging risk factors were simultaneously present, including hypokalemia that was the most common (52%). Anti-Ro/SSA were present in 60% of the subjects, mostly the anti-Ro/SSA-52-kD subtype detected by immuno-Western blotting only. A history of autoimmune disease was found in only 2 of anti-Ro/SSA-positive patients. Experimental data demonstrated that purified anti-Ro/SSA-positive IgGs significantly inhibited IKr and cross reacted with hERG-channel proteins. Moreover, anti-Ro/SSA-positive sera exhibited high reactivity with a peptide corresponding to the hERG-channel pore-forming region. Anti-Ro/SSA may represent a clinically silent novel risk factor for TdP development via an autoimmune-mediated electrophysiological interference with the hERG channel. We propose that TdP patients may benefit from specific anti-Ro/SSA testing even in the absence of autoimmune diseases as immunomodulating therapies may be effective in shortening corrected QT interval and reducing TdP recurrence risk. © 2016 American Heart Association, Inc.

  2. Histamina, receptores de histamina e anti-histamínicos: novos conceitos

    OpenAIRE

    Criado,Paulo Ricardo; Criado,Roberta Fachini Jardim; Maruta,Celina W.; Machado Filho,Carlos d'Apparecida

    2010-01-01

    As drogas com ação anti-histamínica estão entre as medicações mais comumente prescritas na prática dermatológica diária, tanto em adultos como em crianças. Este artigo aborda os novos conceitos da função dos receptores de histamina (receptores H1) e discute os efeitos anti-inflamatórios dessas drogas. A segunda geração de anti-histamínicos difere da primeira geração devido a sua elevada especificidade e afinidade pelos receptores H1 periféricos e devido a seu menor efeito no sistema nervoso c...

  3. Charles de Gaulle, anti-hegemonic discourse and international law

    OpenAIRE

    Dhondt, Frederik

    2015-01-01

    French President Charles de Gaulle (1890-1970) was a controversial figure on the international scene during the Cold War. He steered an original and provocative course bordering on independence from the bipolar structure of post-1945 world politics. De Gaulle’s combination of national independence and a global appeal to state sovereignty casts a long shadow over foreign policy debates in France and in Europe. Although his references to the long run of geopolitics, to history or to “Grandeur” ...

  4. Efeito do anti-TNF-α em implantes endometriais no peritônio de ratas

    Directory of Open Access Journals (Sweden)

    William Kondo

    Full Text Available OBJETIVO: Avaliar o efeito da terapia anti-TNF-α no tratamento de implantes endometriais no peritônio de ratas. MÉTODOS: Os implantes endometrióticos foram induzidos cirurgicamente em 120 ratas Wistar-Albino. Os animais foram aleatoriamente distribuídos em 4 grupos. O grupo C (n=36 recebeu uma injeção intraperitoneal de 0,2ml de solução salina. O grupo L (n=41 recebeu uma injeção subcutânea de 1mg/kg de leuprolide. O grupo I5 (n=20 recebeu uma injeção subcutânea de 5mg/kg de anticorpo monoclonal anti-fator de necrose tumoral (TNF a (infliximab. O grupo I10 (n=20 recebeu uma injeção subcutânea de 10mg/kg de infliximab. As ratas foram sacrificadas após 21 dias para se avaliar o tamanho dos implantes e a expressão do TNF-α. RESULTADOS: O tratamento com leuprolide promoveu uma redução absoluta na área de superfície do implante comparado com o grupo C (+14mm vs. 0mm; p=0,013 e com o grupo I10 (+14mm vs. +5mm; p=0,018. Da mesma forma, uma redução percentual da area de superfície do implante foi observada comparando o grupo L com o grupo C (+33,3% vs. 0%; p=0,005 e com o grupo I10 (+33,3% vs. +18,3%; p=0,027. O tratamento com infliximab não foi capaz de diminuir a área de superfície do implante comparado com o grupo C. A expressão de TNF-α reduziu nos grupos L, I5 e I10 comparado com o grupo C (505,6µm² vs. 660,5µm² vs. 317,2µm² vs. 2519,3µm², respectivamente; p<0,001. CONCLUSÃO: A terapia anti-TNF-α reduziu a expressão de TNF-α nos implantes endometrióticos mas não reduziu a área de superfície da lesão.

  5. Bridge ice accretion and de- and anti-icing systems: A review

    DEFF Research Database (Denmark)

    Kleissl, Kenneth; Georgakis, Christos

    2010-01-01

    in turn lead to severe financial losses. This paper presents a review of the different de- and anti-icing techniques, already developed or in development, which could be applied to bridge cables or pylons. Furthermore, the fundamentals of icing caused by freezing precipitation and in-cloud icing...

  6. The effect of anti-hypertensive drugs on the obstructive pancreatitis in rats Efeitos de fármacos anti-hipertensivos sobre pancreatite obstrutiva em ratos

    Directory of Open Access Journals (Sweden)

    Roberto de Barros Silva

    2010-10-01

    Full Text Available PURPOSE: To investigate the effect of ACE inhibitor, lisinopril and AT1 blocker, losartan, on the obstructive pancreatitis in rat. METHODS: Acute pancreatitis in rats (n=21 was induced for a common hepatic duct were ligated proximal to its entry into the pancreas and the common bile - pancreatic duct were also ligated near its junction with the duodenum, under ether anesthesia, after which the abdomen were closed. The animals was divided in tree groups, being two treated and control group. The animals was treated with Losartan and Lisinopril at the dose of 10µg/Kg body weight per day, i.p., in a proportional volume, for five days, before and after treatement. RESULTS: The inflammation, collagen deposition in the pancreas of treated animals were smaller, suggesting that the use of antihypertensive agents interfered positively in the depletion of the injury of the pancreas. Scythe showed a correlation between activity of pancreatic stellate cells (PSCs lower in treated animals when compared to control. CONCLUSION: The pancreatic stellate cells strength are involved in collagen production during acute pancreatitis and why antihypertensive drugs such as lisinopril and losartan may possibly have beneficial effects in reducing pancreatic fibrosis in models of experimental obstructive pancreatitis.OBJETIVO: Investigar o efeito de um inibidor da ECA, lisinopril e bloqueador AT1, losartan, a pancreatite obstrutiva em ratos. MÉTODOS: Pancreatite aguda em ratos (n = 21 foi induzida por um ducto hepático comum foram ligados proximal à sua entrada no pâncreas e da bílis comum - ducto pancreático também foram ligados perto de sua junção com o duodeno, sob anestesia com éter, após o que abdome foram fechadas. Os animais foram divididos em três grupos, sendo dois tratados eo grupo controle. Os animais foram tratados com lisinopril e losartan na dose de 10µg/Kg de peso corporal por dia, IP, em um volume proporcional, por cinco dias, antes e depois

  7. Soroprevalência de anticorpos anti-Toxoplasma gondii em trabalhadores de um matadouro de suínos e em indivíduos com outras atividades na cidade de Palmas, Paraná, Brasil Seroprevalence of anti-Toxoplasma gondii antibodies in workers of a swine slaughterhouse and in individuals with other activities in the city of Palmas, Paraná, Brazil

    Directory of Open Access Journals (Sweden)

    Patricia Riddell Millar

    2007-02-01

    Full Text Available O risco de infecção por Toxoplasma gondii em trabalhadores de um frigorífico de suínos em Palmas, Paraná, Brasil, foi estudado comparativamente a outros indivíduos que não mantinham contato com animais e suas carcaças. As 174 amostras de soros foram divididas em dois grupos: grupo 1 - funcionários de um matadouro-frigorífico de suínos (133 e grupo 2 - controle (41. No ato da coleta, todos os participantes responderam a um questionário epidemiológico com as seguintes variáveis: sexo, idade, contato com gatos e solo, hábito de ingerir carne crua ou mal cozida, embutidos crus e leite cru. Todas as amostras de soros foram submetidas aos testes ELISA (Enzyme linked immunosorbent assay e RIFI (Reação de imunofluorescência indireta - IgG anti-T. gondii; por sua vez, para IgM anti-T. gondii, foi utilizada a RIFI. Todos os 174 indivíduos eram IgM soro não-reagentes. No grupo 1, 48,1% eram IgG sororreagentes na RIFI e 58,6% na ELISA. No grupo 2, 39,0% eram IgG sororreagentes na RIFI e 51,2% na ELISA. Não foram observadas diferenças estatisticamente significativas entre os grupos 1 e 2 em todas as variáveis, com exceção de "contato com gatos", para o grupo 1, e de "ingestão de leite cru", para o grupo 2, que foram estatisticamente significativas. Os resultados sugerem que a manipulação de carcaças (cistos não deve ter sido o único mecanismo de infecção envolvido na alta freqüência de sororeagentes na população estudada, embora possa ter contribuído na transmissão do parasita como fator de risco, assim como o contato com solo contaminado ou com gatos (oocistos.The risk of Toxoplasma gondii infection in workers of a swine slaughterhouse in Palmas, Paraná, Brazil was compared to other individuals not exposed to these animals and its carcasses. The 174 serum samples were divided in two groups: group 1 - slaughterhouse workers (133, and group 2 - control (41. During blood sampling, workers answered an epidemiological

  8. An International Standard for specifying the minimum potency of anti-D blood-grouping reagents: evaluation of a candidate preparation in an international collaborative study

    NARCIS (Netherlands)

    Thorpe, S. J.; Fox, B.; Heath, A. B.; Scott, M.; de Haas, M.; Kochman, S.; Padilla, A.

    2006-01-01

    The aim of this study was to evaluate a lyophilized monoclonal immunoglobulin M (IgM) anti-D preparation for use as an International Standard to specify a recommended minimum acceptable potency of anti-D blood-grouping reagents. The candidate International Standard (99/836) for specifying the

  9. Exercices de grammaire et travail de groupe (Grammar Exercises and Group Work)

    Science.gov (United States)

    Eluerd, Roland

    1977-01-01

    A discussion of pedagogical models and modes of communication as these apply to the adaptation of grammar exercises to group work. The model used is the small homogeneous group. Various types of exercises are suggested and the relevance of this procedure to communication is discussed. (Text is in French.) (AMH)

  10. Structure-Activity Relationship of Curcumin: Role of the Methoxy Group in Anti-inflammatory and Anticolitis Effects of Curcumin.

    Science.gov (United States)

    Yang, Haixia; Du, Zheyuan; Wang, Weicang; Song, Mingyue; Sanidad, Katherine; Sukamtoh, Elvira; Zheng, Jennifer; Tian, Li; Xiao, Hang; Liu, Zhenhua; Zhang, Guodong

    2017-06-07

    Curcumin, a dietary compound from turmeric, has beneficial effects on inflammatory diseases such as inflammatory bowel disease. Most previous studies have focused on the structure-activity relationship of the thiol-reactive α,β-unsaturated carbonyl groups of curcumin, so little is known about the roles of methoxy groups in biological activities of curcumin. Here we synthesized a series of curcumin analogues with different substitution groups (R = H-, Br-, Cl-, F-, NO 2 -, CH 3 -, and OH-) to replace the methoxy group and evaluated their biological effects in vitro and in vivo. Curcumin, Cur-OH, and Cur-Br (25 μM) suppressed 74.91 ± 0.88, 77.75 ± 0.89, and 71.75 ± 0.90% of LPS-induced NO production, respectively (P 0.05). In the dextran sulfate sodium (DSS)-induced colitis mouse model, the Cur-Br analogue also showed a beneficial effect the same as curcumin (P 0.05). Together, the analogues have dramatically different effects on inflammation, supporting that the substitution group on the methoxy position plays an important role in the anti-inflammatory effects of curcumin. The methoxy group is a potential structural candidate for modification to design curcumin-based drugs for inflammatory diseases.

  11. The C8 side chain is one of the key functional group of Garcinol for its anti-cancer effects.

    Science.gov (United States)

    Zhou, Xin-Ying; Cao, Jing; Han, Chao-Ming; Li, Shu-Wen; Zhang, Chen; Du, Yin-Duan; Zhou, Qian-Qian; Zhang, Xin-Yan; Chen, Xin

    2017-04-01

    Garcinol from the fruit rind of Garcinia indica shows anti-carcinogenic and anti-inflammatory properties, but its mechanism and key functional groups were still need to be identified. Our previous computer modeling suggested that the C8 side chain of Garcinol is so large that it may influence the bioactivity of the compound. 8-Me Garcinol, a derivative of Garcinol in which the bulky side chain at the C8 position of Garcinol is replaced with a much smaller methyl group, was synthesized through a 12-step procedure starting from 1,3-cyclohexanedione. The antitumor activity of Garcinol and 8-Me Garcinol was evaluated in vitro by MTT, cell cycle and cell apoptosis assays. The results showed that 8-Me Garcinol had weaker inhibitory activity on cells proliferation, and little effects on cell cycle and apoptosis in oral cancer cell line SCC15 cells when compared with Garcinol. All of the results indicated 8-Me Garcinol exerts weaker antitumor activity than Garcinol, and the C8 side chain might be an important active site in Garcinol. Changing the C8 side chain will affect the inhibitory effect of Garcinol. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Kids Say the Funniest Things...Anti-Homophobia Group Work in the Classroom

    Science.gov (United States)

    Solomon, Steven

    2004-01-01

    For well over 12 years the Human Sexuality Program within Social Work Services of the Toronto District School Board has been serving lesbian, gay, bisexual and/or transgender (LGBT) students, teachers, parents and their families. Alongside individual, family and group support to the LGBT communities in the board, the program has also been…

  13. Estado actual y futuro de la terapia anti-leishmaniásica en Colombia

    Directory of Open Access Journals (Sweden)

    Jaime Soto

    2006-10-01

    Full Text Available Los antimoniales pentavalentes son la primera elección para el tratamiento de la leishmaniasis en Colombia pero la dosis ha tenido que incrementarse en mas de 600% para mantener su eficacia que en distintos reportes varía entre 93 y 25%, lo cual puede reflejar diferencias en la sensibilidad de los parásitos pero más probablemente incumplimiento de los esquemas recomendados. Los resultados de su empleo, así como la situación actual de pentamidina, anfotericina B y miltefosina son revisados y se hace una proyección sobre el desarrollo de la terapia en los próximos años. Para definir el real estado de la respuesta a los medicamentos anti-leishmaniásicos y prolongarles su vida útil, es indispensable establecer mecanismos de vigilancia de los factores implicados en el manejo de la enfermedad por lo que se plantea una estrategia de sitios centinela que permitan observaciones puntuales en el tiempo, en áreas específicas y sobre situaciones particulares.

  14. De Sitter universes and the emerging landscape in string theory

    Indian Academy of Sciences (India)

    0011, 013 (2000); arXiv:hep-th/0006204. [5] S Gukov, C Vafa and E Witten, Nucl. Phys. B584, 69 (2000); arXiv:hep-th/9906070. T Taylor and C Vafa, Phys. Lett. B474, 130 (2000); arXiv:hep-th/9912152. [6] S B Giddings, S Kachru and J Polchinski, Phys. Rev. D66, 106006 (2002); arXiv:hep- th/0105097. [7] E Witten, Nucl.

  15. Cosmological α-attractors and de Sitter landscape

    Science.gov (United States)

    Scalisi, Marco

    2015-12-01

    We provide a unified description of cosmological α-attractors and late-time acceleration, in excellent agreement with the latest Planck data. Our construction involves two superfields playing distinctive roles: one is the dynamical field and its evolution determines inflation and dark energy, the other is nilpotent and responsible for a landscape of vacua and supersymmetry breaking. We prove that the attractor nature of the theory is enhanced when combining the two sectors: cosmological attractors are very stable with respect to any possible value of the cosmological constant and, interestingly, to any generic coupling of the inflationary sector with the field responsible for uplifting. Finally, as related result, we show how specific couplings generate an arbitrary inflaton potential in a supergravity framework with varying Kähler curvature.

  16. Resistência de helmintos gastrintestinais de bovinos a anti-helmínticos no Planalto Catarinense Anthelmintics resistance of bovine gastrointestinal helminths in Santa Catarina Plateau

    Directory of Open Access Journals (Sweden)

    Antonio Pereira de Souza

    2008-08-01

    Full Text Available Com o objetivo de avaliar focos de resistência de helmintos gastrintestinais parasitos de bovinos, com aptidão para corte, à ivermectina, ao fosfato de levamisole e ao sulfóxido de albendazole foram realizadas avaliações em 39 propriedades localizadas no Planalto Catarinense. Em cada uma foram coletadas, em média, 60 amostras de fezes de animais, com idade entre sete e 18 meses, para avaliar o número de ovos por grama de fezes (OPG, o cultivo e a identificação de larvas. Foram formados três grupos de animais com média de OPG semelhante. A média de OPG de todos os animais coletados, antes do tratamento, foi considerada como testemunha. Cada grupo recebeu um tratamento diferente por via subcutânea (ivermectina na dose de 0,2mg kg-1, fosfato de levamisole na dose de 5mg kg-1 e sulfóxido de albendazole na dose de 2,5mg kg-1. Sete dias após foram repetidas as avaliações por grupo. Considerou-se resistência quando a eficácia da droga foi menor que 95% e o limite inferior do intervalo de confiança IC95% menor que 90%. Entre as propriedades avaliadas, 82,1% apresentaram animais com helmintos resistentes à ivermectina, 15,4% ao fosfato de levamisole e 7,8% ao sulfóxido de albendazole. Em apenas 10,3% das propriedades, a eficácia de todos os anti-helmínticos foi superior a 95%. Com base no diagnóstico genérico, verificou-se que os gêneros predominantes resistentes à ivermectina foram Cooperia spp e Haemonchus spp, ao fosfato de levamisole, Ostertagia spp, Cooperia spp e Trichostrongylus spp, e ao sulfóxido de albendazole, Cooperia spp.In order to estimate possible focus of resistance of bovine gastrointestinal helminths to ivermectin, levamisole phosphate and albendazole sulphoxide, 39 properties in the Santa Catarina Plateau were evaluated. In each location a mean number of 60 samples of feces was collected from animals between seven and 18 months of age, for the evaluation of the number of eggs per gram of feces (EPG, for

  17. Prospective risk analysis of the anti-infective medication administration process Análisis prospectivo de riesgo del proceso de administración de medicamentos anti-infecciosos Análise prospectiva de risco do processo de administração de medicamentos anti-infecciosos

    Directory of Open Access Journals (Sweden)

    Ana Elisa Bauer de Camargo Silva

    2013-02-01

    Full Text Available OBJECTIVE: The objective of this study was to analyze the potential risks involved in the administration process of intravenous anti-infective medication at a medical clinic, using the Failure Mode and Effect Analysis. METHOD: This exploratory study was conducted at the medical clinic of a hospital in the State of Goiás. For data collection we convened a team comprised of six professionals involved in medication treatment: a doctor, nurse, nursing technician, pharmacist, a nursing and a risk manager. A total of 24 meetings were held, for a total of 56 hours. The data were transcribed into an electronic database within Microsoft Excel®, and the Xfmea4 software was used. RESULT: The results indicated 52 failure modes, 79 effects of failure, and 285 causes of failure. The causes were related to: the management of organizational processes, human resources, physical and material structure. A total of 298 actions for improvement were recommended for 215 causes of high and average priority, 81.9% of which were short-term priorities. The simulation of the impact of the proposed interventions revealed a 79.7% reduction of the high-priority failure modes. CONCLUSION: It was concluded that the study identified potential risks to patients and recommended proactive actions, of rapid application and low cost, evaluated positively in the reduction of risk of occurrence of avoidable incidents, increasing reliability and safety of the medication administration process. Studies like this demonstrate that, with the application of a method of risk analysis, nurses can effectively assist in preventing medication incidents.OBJETIVO: Este estudio objetivó analizar los riesgos potenciales de administración de medicamentos anti-infecciosos por vía endovenosa en una unidad de Clínica Médica, utilizando el Método de Análisis del Modo y Efecto de Falla. MÉTODO: De naturaleza exploratoria, se realizó en la Clínica Médica de un Hospital del Estado de Goi

  18. Anti-HBc testing for blood donations in areas with intermediate hepatitis B endemicity Detección de anticuerpos anti-HBc en sangre donada en lugares donde la hepatitis B tiene endemicidad intermedia

    Directory of Open Access Journals (Sweden)

    Celina Maria Turchi Martelli

    1999-07-01

    Full Text Available En otros estudios se ha evaluado el menor riesgo de infecciones transmitidas por transfusión sanguínea que acarrea el tamizaje de anticuerpos contra los antígenos nucleares de la hepatitis B (anti-HBc, sumado a la prueba detectora de antígenos de superficie (HbsAg. No obstante, la mayoría de estos estudios se basaron en datos procedentes de zonas con baja endemicidad por hepatitis B o de bancos de sangre de países desarrollados, donde la mayoría de la sangre proviene de personas que han donado previamente. A fin de examinar los pros y los contras del tamizaje de anticuerpos anti-HBc en el Brasil, los autores describen los antecedentes y la interpretación de las pruebas de tamizaje para prevenir la hepatitis postransfusión. También presentan los datos sobre el tamizaje de la hepatitis B en todas las regiones del Brasil. No hay pruebas suficientes para suspender el tamizaje de los anticuerpos anti-HBc en el país. Debe darse alta prioridad a comparar el costo-efectividad de un marcador basado en la biología molecular con el de la actual prueba detectora de anticuerpos anti-HBc aplicada comúnmente, a fin de mejorar las medidas de tamizaje que garantizan la inocuidad de la sangre.

  19. Mobile app for human-interaction with sitter robots

    Science.gov (United States)

    Das, Sumit Kumar; Sahu, Ankita; Popa, Dan O.

    2017-05-01

    Human environments are often unstructured and unpredictable, thus making the autonomous operation of robots in such environments is very difficult. Despite many remaining challenges in perception, learning, and manipulation, more and more studies involving assistive robots have been carried out in recent years. In hospital environments, and in particular in patient rooms, there are well-established practices with respect to the type of furniture, patient services, and schedule of interventions. As a result, adding a robot into semi-structured hospital environments is an easier problem to tackle, with results that could have positive benefits to the quality of patient care and the help that robots can offer to nursing staff. When working in a healthcare facility, robots need to interact with patients and nurses through Human-Machine Interfaces (HMIs) that are intuitive to use, they should maintain awareness of surroundings, and offer safety guarantees for humans. While fully autonomous operation for robots is not yet technically feasible, direct teleoperation control of the robot would also be extremely cumbersome, as it requires expert user skills, and levels of concentration not available to many patients. Therefore, in our current study we present a traded control scheme, in which the robot and human both perform expert tasks. The human-robot communication and control scheme is realized through a mobile tablet app that can be customized for robot sitters in hospital environments. The role of the mobile app is to augment the verbal commands given to a robot through natural speech, camera and other native interfaces, while providing failure mode recovery options for users. Our app can access video feed and sensor data from robots, assist the user with decision making during pick and place operations, monitor the user health over time, and provides conversational dialogue during sitting sessions. In this paper, we present the software and hardware framework that

  20. Detection of Anti-Paracoccidioides brasiliensis antibodies in suspected tuberculosis patients = Detecção de anticorpos anti-Paracoccidioides brasiliensis em pacientes suspeitos de tuberculose

    Directory of Open Access Journals (Sweden)

    Maria Luiza Dias Fraga Peron

    2010-07-01

    Full Text Available Paracoccidioidomycosis (PCM is an important systemic mycosis in LatinAmerica that occurs as active disease in 1-2% of Paracoccidioides brasiliensis infected people. Like PCM, tuberculosis (TB affects mainly the lungs and the clinical and radiological aspects do notalways allow differentiation between them. The aim of this study was to carry out serological investigation for detecting anti-P. brasiliensis antibodies, by three serological methods, in patientswith symptoms suggestive of pulmonary TB. From August 2005 to September 2006, 76 patients with pulmonary symptoms suspected for TB were attended at the Regional Specialties Center Laboratory in the city of Paranavaí, Paraná, Brazil and submitted to microbiological TB research, ELISA, immunodiffusion and immunoblotting for PCM. Of all the individuals, 21 (27.63% were reactive to P. brasiliensis by ELISA and 11 (14.47% showed a laboratory diagnosis of pulmonary TB. Of all the individuals serologically reactive to P. brasiliensis, by ELISA, none had positive results by immunodiffusion and one reacted with antigen 43 kDa when Immunobloting was carried out. Our results lead us to reflect a necessity to obtain a more specific serologic test for diagnosis of PCM disease in patients with respiratory symptoms considering the high number of individuals reactive to P. brasiliensis especially in endemic areas.Paracoccidioidomicose (PCM é importante micose sistêmica na América Latina, que ocorre como doença ativa em 1-2% dos indivíduos infectados com Paracoccidioides brasiliensis. Assim como a PCM, a tuberculose (TB afeta principalmente os pulmões, porém os aspectos clínicos e radiológicos nem sempre permitem a diferenciação entreessas doenças. O objetivo deste estudo foi realizar um inquérito sorológico para a detecção de anticorpos anti-P. brasiliensis, utilizando três métodos sorológicos, em pacientes com sintomassugestivos de tuberculose pulmonar. De agosto de 2005 a setembro de

  1. High-throughput identification of chemical inhibitors of E. coli Group 2 capsule biogenesis as anti-virulence agents.

    Directory of Open Access Journals (Sweden)

    Carlos C Goller

    Full Text Available Rising antibiotic resistance among Escherichia coli, the leading cause of urinary tract infections (UTIs, has placed a new focus on molecular pathogenesis studies, aiming to identify new therapeutic targets. Anti-virulence agents are attractive as chemotherapeutics to attenuate an organism during disease but not necessarily during benign commensalism, thus decreasing the stress on beneficial microbial communities and lessening the emergence of resistance. We and others have demonstrated that the K antigen capsule of E. coli is a preeminent virulence determinant during UTI and more invasive diseases. Components of assembly and export are highly conserved among the major K antigen capsular types associated with UTI-causing E. coli and are distinct from the capsule biogenesis machinery of many commensal E. coli, making these attractive therapeutic targets. We conducted a screen for anti-capsular small molecules and identified an agent designated "C7" that blocks the production of K1 and K5 capsules, unrelated polysaccharide types among the Group 2-3 capsules. Herein lies proof-of-concept that this screen may be implemented with larger chemical libraries to identify second-generation small-molecule inhibitors of capsule biogenesis. These inhibitors will lead to a better understanding of capsule biogenesis and may represent a new class of therapeutics.

  2. Gravitation as Gauge theory of Poincare Group

    International Nuclear Information System (INIS)

    Stedile, E.

    1982-08-01

    The geometrical approach to gauge theories, based on fiber-bundles, is shown in detail. Several gauge formalisms for gravitation are examined. In particular, it is shown how to build gauge theories for non-semisimple groups. A gravitational theory for the Poincare group, with all the essential characteristics of a Yang-Mills theory is proposed. Inonu-Wigner contractions of gauge theories are introduced, which provide a Lagrangian formalism, equivalent to a Lagrangian de Sitter theory supplemented by weak constraints. Yang and Einstein theories for gravitation become particular cases of a Yang-Mills theory. The classical limit of the proposed formalism leads to the Poisson equation, for the static case. (Author) [pt

  3. Jesús de Polanco and the Prisa Group

    Directory of Open Access Journals (Sweden)

    Mercedes Cabrera

    2018-01-01

    Full Text Available The main goal of this article is to present Jesús de Polanco’s (1929–2007 successive business initiatives that culminated in the expansion of the PRISA Group (Promotora de Informaciones S.A., which was the leading Spanish multi-media group of its time.  As well as the interest that his career triggers, Polanco’s biography allows us to address the relationship between the company and politics during the closing decades of the Franco dictatorship and the transition to democracy from a concrete perspective. Those were years marked by profound transformations, not only in the political life of the country but also in its economy, society and business structures that affected the entire communications media sector.

  4. LEP Celebration : Groupe de Jazz "Wolfgang & The Werewolves"

    CERN Document Server

    CERN. Geneva

    2000-01-01

    At 14:00: Groupe de Jazz "Wolfgang & The Werewolves" . The official programme begins at 15:00 with an introduction from the Director General, and Professor Martinus Veltman will give the keynote speech. Heads of national delegations represented at ministerial level will then make their speeches, following which a commemorative plaque will be unveiled. A specially commissioned ballet by Maurice Béjart will bring the ceremony to a close.

  5. On the large subgroups of O(n-1,1) and a result by Kowalsky and Witte

    Science.gov (United States)

    Patrangenaru, Vic

    2013-02-01

    One shows that the maximal Lie subgroups of the Lorentz group O(n-1,1) of first and second largest possible dimensions are the groups of Lorentz transformations that leave invariant a vector hyperplane in the Minkowski space. One also shows that the only Lorentz manifolds that admit an almost simple transitive group of isometries with a noncompact stabilizer are the de-Sitter and the anti de-Sitter spaces.

  6. O uso de anti-retrovirais em gestantes modifica o perfil lipídico?

    Directory of Open Access Journals (Sweden)

    El Beitune Patrícia

    2003-01-01

    Full Text Available OBJETIVO: avaliar o efeito das medicações anti-retrovirais sobre o metabolismo lipídico em gestantes portadoras do HIV. MÉTODOS: estudo prospectivo realizado em 57 gestantes que foram divididas em três grupos: grupo AZT, com 20 pacientes portadoras do HIV em uso de AZT; grupo TT, com 25 pacientes portadoras do HIV em uso de esquemas contendo três anti-retrovirais (AZT + 3TC + NFV e grupo controle, com 12 pacientes. Os dados demográficos e antropométricos foram homogêneos entre os grupos estudados. Foram excluídas as pacientes com antecedentes pessoais ou familiares de hiperlipidemia. Amostras sanguíneas foram obtidas para avaliação dos lipídeos (colesterol total, frações LDL e HDL-colesterol e triglicerídeos em quatro oportunidades durante a gravidez (1º = 14-20 semanas; 2º = 21-26 semanas; 3º = 27-32 semanas e 4º = 33-38 semanas. Os dados foram analisados utilizando-se os testes não paramétricos do chi², teste de Friedman e teste de Kruskal-Wallis. RESULTADOS: o uso de anti-retrovirais durante a gestação não induziu diferenças nas taxas do colesterol total e HDL, no entanto, o uso destes agentes esteve associado a elevação de 76,5 mg/dL e 84 mg/dL para 96 mg/dL e 105 mg/dL na concentração da fração LDL-colesterol para os grupos AZT e TT, respectivamente (p<0,01. Observou-se associação positiva significante entre os triglicerídeos e a carga viral nas gestantes do grupo AZT (r = 0,53; p = 0,015. CONCLUSÃO: a utilização dos anti-retrovirais durante a gestação eleva significativamente a concentração da lipoproteína LDL. Persistem as dúvidas se a gestação potencializa a longo prazo os efeitos dos anti-retrovirais sobre o metabolismo lipídico.

  7. Efeito das drogas anti-retrovirais sobre as taxas de fertilidade de ratas Wistar Effects of antiretroviral drugs on fertility of Wistar rats

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    Ernesto Antonio Figueiró Filho

    2002-12-01

    Full Text Available OBJETIVO: avaliar os efeitos de drogas anti-retrovirais isoladas e em associação sobre as taxas de fertilidade em ratas prenhes expostas a estes fármacos, bem como o efeito perinatal nas crias. MÉTODOS: foram utilizadas ratas fêmeas prenhes adultas da raça Wistar, pesando inicialmente entre 200 e 230 g. Foram testadas a azidotimidina (AZT, lamivudina (3TC e nelfinavir (NFV, cujas dosagens foram padronizadas em 10 vezes a dose normalmente utilizada em gestantes, proporcionalmente ao peso dos animais. No total foram avaliados sete grupos, incluindo o controle. O início da experimentação foi o dia zero da prenhez e as cesarianas foram realizadas com 21 dias de prenhez. Para o cálculo das taxas de fertilidade, avaliaram-se o número de fetos vivos e mortos, sítios de implantação e número de corpos lúteos. Utilizaram-se o teste t de Student e Mann-Whitney para a análise estatística. RESULTADOS: não houve alterações significativas nas taxas de perdas pré-implantação e da eficiência de implantação de ratas tratadas com anti-retrovirais isolados e em associação. No entanto, houve aumento significativo nas taxas de perdas pós-implantação (grupo controle: 7,6%; grupos medicamentos: de 20,2 a 26,7%, redução significativa nas taxas de viabilidade fetal (grupo controle: 92,4%; grupos medicamentos: de 73,3 a 79,8% e redução significativa no número de fetos por ninhada (grupo controle: 14,7, grupos medicamentos: de 11,1 a 12,7. Observou-se também que houve redução do peso materno e dos fetos nos grupos tratados com 3TC, AZT + 3TC e AZT + 3TC + NFV. CONCLUSÃO: com a utilização de doses elevadas de medicamentos anti-retrovirais na presente casuística, efeitos importantes sobre a fertilidade foram encontrados, o que sinaliza para a necessidade de se pesquisarem outros fármacos anti-retrovirais com menor potencial histotóxico e que possam, com segurança, ser utilizados por gestantes portadoras da infecção pelo v

  8. Miller, Karina. Escrituras Impolíticas. Anti-representaciones de la comunidad en Juan Rodolfo Wilcock, Osvaldo Lamborghini y Virgilio Piñera. Pittsburgh: Instituto Internacional de Literatura Iberoamericana Universidad de Pittsburgh, 2013. Print. 155 pp.

    OpenAIRE

    Del Toro, José César

    2017-01-01

    Miller, Karina. Escrituras Impolíticas. Anti-representaciones de la comunidad en Juan  Rodolfo Wilcock, Osvaldo Lamborghini y Virgilio Piñera. Pittsburgh: Instituto Internacional de Literatura Iberoamericana Universidad de Pittsburgh, 2013. Print. 155 pp.

  9. Características testiculares de touros imunizados com vacina anti-hormônio liberador do hormônio luteinizante Testicular characteristics of bulls immunosterilized with anti-luteinizing hormone-releasing hormone vaccine

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    Ricardo Zanella

    2009-10-01

    Full Text Available O objetivo deste trabalho foi avaliar a ação imunoesterilizadora de uma vacina anti-hormônio liberador de hormônio luteinizante (LHRH, composta por ovalbumina-LHRH-7 e tiorredoxina-LHRH-7, em touros mestiços Nelore. Vinte e seis touros, com dois anos de idade, foram distribuídos aleatoriamente em dois grupos de 13 animais. No grupo I, os animais receberam uma dose e dois reforços da vacina nos dias 0, 141, e 287 do experimento. No grupo II, os animais não receberam nenhum tratamento (controle. Para avaliar o efeito da vacina nos touros, foi realizada a mensuração da circunferência escrotal no início do experimento e no dia do abate, 741 dias depois. Por ocasião do abate, também foi coletada uma amostra dos testículos para avaliação histológica. O grupo imunizado apresentou circunferência escrotal ao abate de 22±5,98 cm, menor do que a do grupo controle que foi de 35,6±2,4 cm. Na análise histológica dos animais do grupo imunizado, foi observada degeneração testicular com ausência de espermatozoides em 85% dos animais avaliados, os outros 15% apresentaram redução no número de espermatozoides, em comparação aos animais do grupo controle. A vacina anti-LHRH, com fusão de proteínas, é efetiva na castração imunológica de touros e deve ser considerada como alternativa para utilização na produção bovina extensiva no Brasil.The objective of this study was to evaluate the immunosterilization action of the anti-luteinizing hormone-releasing hormone (LHRH vaccine, composed with ovalbumin-LHRH-7 and thioredoxin-LHRH-7, in Nelore-cross bulls. Twenty-six 2-year old bulls were randomly assigned in two groups of 13 animals each. The animals of group I received a primary and two booster injections of the vaccine on days 0, 141, and 287 of the experiment. In group II, the control group, the bulls did not receive any type of treatment. Scrotal circumference was measured in the beginning of the experiment and at slaughter

  10. Potencial anti-Sporothrix spp. de plantas da família lamiaceae

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    Stefanie Bressan Waller

    2015-01-01

    As propriedades terapêuticas das plantas medicinais são cada vez mais estudadas, principalmente devido aos crescentes casos de resistência antimicrobiana, como observado em cepas do Complexo Sporothrix. As plantas da família Lamiaceae são conhecidas por suas propriedades antifúngicas, entretanto, são escassos seus estudos contra agentes causadores da esporotricose. Devido ao potencial promissor dessas plantas, objetivou-se (1) avaliar a atividade anti-Sporothrix spp. in vitro de Origanum vulg...

  11. Patrones de prescripción de antidiabéticos en un grupo de pacientes colombianos Antidiabetic drugs prescription patterns among a group of patients in Colombia

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    Jorge Enrique Machado Alba

    2007-08-01

    Full Text Available OBJETIVOS: Determinar los patrones de prescripción de medicamentos antidiabéticos en un grupo de personas afiliadas al Sistema General de Seguridad Social en Salud (SGSSS de Colombia. MÉTODOS: Se incluyeron en el estudio 7 308 afiliados al SGSSS con diabetes de tipo 1 ó 2, de ambos sexos y de todas las edades, tratados durante por lo menos tres meses (de mayo a julio de 2005 en 19 ciudades colombianas. Se diseñó una base de datos de los registros de consumo de medicamentos de la empresa dispensadora de fármacos. Los datos se analizaron con el paquete estadístico SPSS 13 para Windows, empleando la prueba de la t de Student y el análisis de la varianza (ANOVA para comparar variables cuantitativas y la prueba de la x² para comparar variables categóricas. RESULTADOS: La edad media de los pacientes era de 60,7 ± 12,7 años; el 56,6 % eran mujeres, de edad media significativamente mayor que la de los hombres (P OBJECTIVES: To identify prescription patterns for diabetes treatment among a group of individuals covered by Colombia's universal health care, the General System for Social Security in Health (SGSSS. METHODS: The study included 7 308 patients covered by SGSSS who had diabetes mellitus type 1 or 2, were of either sex, any age, and had been undergoing treatment for at least three months (May-July 2005 in 19 cities in Colombia. A database was compiled from the medication usage records maintained by the dispensing pharmacy. Data were analyzed using SPSS 13.0 (SPSS Inc., Chicago, Illinois, United States of America. Student's t-test and analysis of variance (ANOVA were employed to compare quantitative variables, and the chi-square test was applied to compare categorical variables. RESULTS: The patients' mean age was 60.7 ± 12.7 years. Women made up 56.6% of the group and had a mean age significantly higher than that of the men (P < 0.05. Forty-eight percent of the group had been prescribed one diabetes medication, while 52% had been

  12. Pneumococcal polysaccharide vaccination elicits IgG anti-AB blood group antibodies in healthy individuals and patients with Type I diabetes mellitus

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    Wendelin Wolfram

    2016-11-01

    Full Text Available Hypothesis: Blood group antibodies are natural antibodies that develop early in life in response to cross-reactive environmental antigens in the absence of antigen encounter. Even later in life structural similarities in saccharide composition between environmental antigens such as bacterial polysaccharides and blood group A/B antigens could lead to changes in serum levels, IgM/IgG isotype and affinity maturation of blood group anti-A/B antibodies. We adressed the question whether immunization with pneumococcal polysaccharide (PnP vaccine (PPV Pneumovax®23 could have such an effect in patients with with type I diabetes mellitus (DM I, an autoimmune disease where an aberrant immune response to microbial antigens likely plays a role.Methods: Anti-PnP IgM and IgG responses were determined by ELISA and the Diamed-ID Micro Typing System was used to screen anti-A/B antibody titer before and after Pneumovax®23 immunization in 28 healthy individuals and 16 patients with DM I. In addition, surface plasmon resonance (SPR technology using the Biacore® device and a synthetic blood group A/B trisaccharide as the antigen was applied to investigate IgM and IgG anti-A/B antibodies and to measure antibody binding dynamics. Results: All healthy individuals and DM I patients responded with anti-PnP IgM and IgG antibody production four to six weeks after Pneumovax®23 (Pn23 immunization, while no increase in blood group anti-A/B antibody titer was observed when measured by the Diamed-ID Micro Typing System. Interestingly, isotype-specific testing by SPR-technology revealed an increase in blood group anti-A/B IgG, but not IgM, following Pn23 immunization in both patients and controls. No change in binding characteristics of blood group anti-A/B antibodies could be detected following Pn23 vaccination, supporting the assumption of an increase in IgG antibody titer with no or very little affinity maturation.Conclusion: The study provides evidence for epitope sharing

  13. Formação, práticas e trajetórias de aconselhadores de centros de testagem anti-HIV do Rio de Janeiro, Brasil

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    Claudia Mora

    2015-12-01

    Full Text Available Perante a importância do aconselhamento na testagem anti-HIV, analisamos as diretrizes institucionais, as competências privilegiadas no treinamento profissional e os saberes/práticas de aconselhadores. Trata-se de estudo qualitativo centrado na análise documental, observação e entrevista com aconselhadores de Centros de Testagem e Aconselhamento (CTA do estado do Rio de Janeiro. A análise foi orientada pela teoria de Pierre Bourdieu. Foi evidenciado que o habitus profissional dos aconselhadores resulta da articulação dos treinamentos, da graduação e de experiências e interesses pessoais. A operacionalização de competências, como a escuta ativa, é limitada pela rotina dos serviços e escassez de espaços de reflexão. Para incrementar a prática do aconselhamento, é importante desenvolver competências no treinamento, manter a educação continuada e fazer adequações na rotina do serviço. Tais ajustes podem fortalecer a passagem das diretrizes à ação e o aprimoramento da organização e gestão dos CTA.

  14. Les roches basiques des boutonnieres d'Agadir melloul et d'Iguerda - taifast : tkmoins de l’histoire preorogenique de la chaine panafricaine de l’Anti-Atlas (Maroc

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    El Aouli, E. H.

    2004-04-01

    Full Text Available Dans les boutonnières précambriennes d'Agadir Melloul et d'Iguerda-Taïfast (Anti-Atlas central, les roches basiques du Néoprotérozoïque (PII sont représentées par des dykes et des corps basiques intrusifs dans le socle paléoprotérozoïque (PI et les quartzites du PII. L’ensemble PI, PII et roches basiques est affecté par la schistosité régionale panafricaine. Les éléments en traces, réputés peu mobiles au cours des processus d'altération et de métamorphisme (Nb, Y, Zr, Ti, V et les terres rares ont permis de subdiviser ces roches basiques en deux groupes: un groupe tholeiitique et un groupe transitionnel. Le cadre géodynamique de mise en place de ces roches pourrait être lié à un contexte distensif marquant le rifting pré-panafricain en relation avec l’ouverture océanique reconnue dans la boutonnière de Bou Azzer-El Grara et dans le massif de Siroua.En los complejos precámbricos de Agadir Melloul y de Iguarda-Taifast (Anti-Atlas centro, las rocas básicas del Neoproterozoico (PII están representadas por diques y cuerpos básicos intmsivos en el zócalo Paleoproterozoico (PI y las cuarcitas del PII. El conjunto PI, PII y las rocas básicas está afectado por la esquistosidad regional panafricana. Los elementos traza incompatibles, poco móviles en el transcurso de procesos de alteración y de metamorfismo (Nb, Y, Zr, Ti, V, así como las tierras raras, permiten subdividir estas rocas básicas en dos grupos: un grupo toleítico y otro transicional. El marco geodinámico de la intrusion de estas rocas podria estar ligado a un contexto extensional asociado al rifting pre-panafricano en relación con la apertura oceánica reconocida en el complejo de Bou Azzer-El Graara y en el macizo de Siroua.

  15. Asociación entre la presencia de anticuerpos anti-Ras y anti-VPH16 E4/E7 y lesiones intraepiteliales del cérvix

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    Vázquez-Corzo Sara

    2003-01-01

    Full Text Available OBJETIVO: Determinar si anticuerpos séricos contra E4, E7 y Ras pueden ser utilizados como marcadores de lesiones tempranas del cérvix uterino asociadas al virus del papiloma humano. MATERIAL Y MÉTODOS: Entre marzo de 1999 y abril de 2000 se realizó un estudio sero-epidemiológico de casos y controles en la clínica de displasias del Hospital General Doctor Gea González, en la Ciudad de México, en 116 muestras de suero para evaluar la presencia de anticuerpos anti-E4, E7 y Ras utilizando un ELISA de captura. Se estimaron razones de momios e intervalos de confianza de 95% RESULTADOS: Anticuerpos anti-E7 se asociaron a mujeres con lesiones NIC III, mientras que anticuerpos anti-E4 y anti-Ras fueron más frecuentes en lesiones NIC I-II. Al evaluar el perfil de anticuerpos que presentaron las mujeres, encontramos que a anticuerpos contra dos proteínas predicen la existencia de una lesión NIC I-II, y b la presencia de tres anticuerpos predicen una lesión NIC III. CONCLUSIONES: La detección de anticuerpos séricos contra E4, E7 y Ras en combinación con otras técnicas de diagnóstico, podrían ser de utilidad para detectar oportunamente a mujeres con lesiones tempranas asociadas al Virus del Papiloma Humano y en riesgo de desarrollar cáncer.

  16. Occurrence of anti-Toxoplasma gondii antibodies in cattle and pigs slaughtered, State of Rio de Janeiro Ocorrência de anticorpos anti-Toxoplasma gondii em bovinos e suínos abatidos, Estado do Rio de Janeiro

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    Daniela Martins Luciano

    2011-12-01

    Full Text Available This study aimed to estimate the occurrence of anti-Toxoplasma gondii antibodies by means of the Indirect Immunufluorescent Antibody Assay (IFAT in cattle and pigs from slaughterhouses in two municipalities in the State of Rio de Janeiro. IgG anti-T. gondii antibodies was found in 1.96% (9/459 of the cattle and 7.64% (31/406 of the pigs, without any positive association (p > 0.05 with risk factors for transmission and seropositivity. Taking the cutoff point of IFAT ³ 1:64, titers of 64 and 256 were detected, suggesting chronic infection. Despite the low prevalence rates found for cattle and pigs, these indicated environmental contamination in the municipalities investigated, biosafety failures at the technified pig farm evaluated and the possibility of human and animal infection through eating raw or undercooked meat from these animals.Este trabalho objetivou estimar a ocorrência de anticorpos anti-Toxoplasma gondii por meio da Reação de Imunofluorescência Indireta (RIFI em bovinos e suínos de abatedouros de dois municípios do Estado do Rio de Janeiro. Anticorpos IgG anti-T. gondii foram encontrados em 1,96% (9/459 dos bovinos e em 7,64% (31/406 dos suínos, sem associação positiva (p > 0,05 em relação aos fatores de risco de transmissão e a soropositividade. Considerando-se o ponto de corte (RIFI ³ 1:64, foram detectados os títulos de 64 e 256, sugestivos de infecção crônica. Apesar de baixas, as prevalências encontradas para bovinos e suínos indicaram contaminação ambiental nos municípios avaliados, falhas na biossegurança da granja tecnificada de suínos e a possibilidade de infecção humana e animal pela ingestão da carne crua ou mal passada desses animais.

  17. Ocorrência de anticorpos anti-Toxoplasma gondii em caprinos de Pitanga, Paraná, Brasil

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    Célia Rosimarie dos Reis

    2007-10-01

    Full Text Available Objetivou-se verificar a prevalência de anticorpos anti-Toxoplasma gondii em soros de caprinos de produção leiteira naturalmente infectados utilizando os testes de imunofluorescência indireta (IFI e o de aglutinação modificada (MAT, determinar a especificidade e a sensibilidade do MAT e avaliar a concordância dos resultados entre os testes. Para o estudo foram coletadas 282 amostras de soro caprino, de propriedades do município de Pitanga, Paraná, região com uma grande pecuária de pequenos ruminantes. A prevalência encontrada pela IFI foi de 44,68% e 23,05% pelo MAT. Houve diferença estatisticamente significativa (p=0,0086 em relação ao sexo dos animais, sendo que as fêmeas foram mais soropositivas. Os resultados de sensibilidade e especificidade para o MAT foram, respectivamente, 42,2% e 94,9%. Na comparação dos resultados foi observada uma concordância moderada (Kappa = 0,42. A alta prevalência da infecção, aliada aos altos títulos obtidos pela IFI e aos sinais clínicos presentes nos rebanhos sugere a toxoplasmose como uma possível causa de problemas reprodutivos em caprinos. Os resultados de sensibilidade e especificidade para o MAT obtidos neste estudo permitem recomendá-lo como teste confirmatório para a espécie caprina.

  18. Pesquisa de anticorpos anti-Neospora spp. e anti-herpersvírus equino em cavalos de tração no município de Santa Maria, RS, Brasil Looking for antibodies anti-Neospora spp. and anti-equine herpersvirus in carter horses in Santa Maria, Brazil

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    Luís Antonio Sangioni

    2011-02-01

    Full Text Available O presente estudo teve como objetivo investigar a ocorrência de anticorpos contra Neospora spp. e o herpesvírus equino (EHV em soros de cavalos de tração de Santa Maria, RS, Brasil. Os soros sanguineos provenientes de 91 animais do projeto de extensão da Universidade Federal de Santa Maria "Programa de Ação Social Amigos do Carroceiro" (PASAC foram colhidos no período de março de 2006 a maio de 2008 e submetidos ao teste de imunofluorescência indireta para detecção de anticorpos anti-Neospora spp. e à técnica de soro neutralização para anticorpos anti-EHV. Constatou-se que 15,4% (14/91 das amostras foram reagentes para o Neospora spp. e não se verificou a presença da infecção pelo herpesvírus equino. Sugere-se a circulação do coccídeo na população equina estudada. Salienta-se a necessidade de estudos adicionais sobre o potencial risco zoonótico e a importância sanitária desse protozoário nos cavalos de tração.This study aimed to investigate the prevalence of antibodies against Neospora spp and equine herpesvirus (EHV among carter horses in Santa Maria, RS, Brazil. Serum samples from 91 horses, involved in the extension project "Programa de Ação Social Amigo do Carroceiro" at Universidade Federal de Santa Maria, were collected from March of 2006 to May of 2008. Immunofluorescence assay was used to detect Neospora spp. and virus neutralization assay to EHV. This research showed 15.4% (14/91 samples were positive to Neospora spp. and no antibodies against EHV were detected. These results suggest the presence of Neospora spp. in carter horses of Santa Maria. Additional studies are needed to determine the zoonotic potential risk and the sanitary importance this protozoan in the population analyzed.

  19. Indicadores de síntomas de abstinencia en un grupo de fumadores mexicanos Withdrawal symptoms indicators in a group of mexican smokers

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    Gabriela Lara-Rivas

    2007-01-01

    Full Text Available OBJETIVO: Identificar indicadores de abstinencia en fumadores de la Clínica Anti-Tabaco en un hospital de referencia. Evaluar los síntomas según el nivel de adicción a la nicotina mediante la escala de Fagerström (EDNF. MATERIAL Y MÉTODOS: Se incluyeron fumadores de la Clínica Anti-Tabaco y no-fumadores visitantes. Fumadores y no-fumadores completaron una entrevista estandarizada y diario de síntomas. RESULTADOS: Se incluyeron 185 fumadores (edad 40.93 años, DE, 10.22, 93 hombres/92 mujeres y 102 no-fumadores (edad 38.22 años, DE 9.40, 41 hombres/61 mujeres. La mediana del índice paquetes-año fue de 13 (rango 1-72, el promedio de la EDNF fue de 6 (DE, 2.35. Los síntomas asociados con la dependencia fueron: ansiedad, RM 1.21 (IC95% 1.03-1.43; depresión, RM 2.75 (IC95%1.07-7.04, la depresión es más común entre las mujeres, RM 2.03 (IC95% 1.10 - 3.75; deseos de fumar, RM 1.53 (IC95% 1.19-1.97 y sudoración, RM 2.73 (IC95% 1.07-6.95. CONCLUSIONES: Los indicadores de abstinencia de nicotina en un grupo de fumadores mexicanos fueron deseos de fumar, ansiedad, depresión y diaforesis; estos síntomas se correlacionan con el nivel de dependencia a la nicotina.OBJECTIVE: To describe symptoms of AS in a group of Mexican smokers attending a third referral clinic, to evaluate symptoms according to degree of nicotine dependence using the Fagerström Test (FTND. MATERIAL AND METHODS: A self-reported standardized questionnaire was administered to smokers and non-smokers during three consecutive days. None of the smokers received treatment during this period. RESULTS: A total of 185 smokers and 102 non-smokers were included. No differences in age or gender were observed. Among smokers, median tobacco consumption was 13 pack-years (range 1 to 72 and the mean (SD FTND was six (2.35. Symptoms related to nicotine withdrawal were anxiety (OR 1.21, 95%IC 1.03-1.43, depression (OR 2.75, 95%IC 1.07-7.04, which was more common in women (OR 2.03, 95%IC 1

  20. Asociación entre la presencia de anticuerpos anti-Ras y anti-VPH16 E4/E7 y lesiones intraepiteliales del cérvix Association between anti-Ras and anti-HPV16 E4/E7 antibodies with cervical intraepithelial lesions

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    Sara Vázquez-Corzo

    2003-10-01

    Full Text Available OBJETIVO: Determinar si anticuerpos séricos contra E4, E7 y Ras pueden ser utilizados como marcadores de lesiones tempranas del cérvix uterino asociadas al virus del papiloma humano. MATERIAL Y MÉTODOS: Entre marzo de 1999 y abril de 2000 se realizó un estudio sero-epidemiológico de casos y controles en la clínica de displasias del Hospital General Doctor Gea González, en la Ciudad de México, en 116 muestras de suero para evaluar la presencia de anticuerpos anti-E4, E7 y Ras utilizando un ELISA de captura. Se estimaron razones de momios e intervalos de confianza de 95% RESULTADOS: Anticuerpos anti-E7 se asociaron a mujeres con lesiones NIC III, mientras que anticuerpos anti-E4 y anti-Ras fueron más frecuentes en lesiones NIC I-II. Al evaluar el perfil de anticuerpos que presentaron las mujeres, encontramos que a anticuerpos contra dos proteínas predicen la existencia de una lesión NIC I-II, y b la presencia de tres anticuerpos predicen una lesión NIC III. CONCLUSIONES: La detección de anticuerpos séricos contra E4, E7 y Ras en combinación con otras técnicas de diagnóstico, podrían ser de utilidad para detectar oportunamente a mujeres con lesiones tempranas asociadas al Virus del Papiloma Humano y en riesgo de desarrollar cáncer.OBJECTIVE: To evaluate whether serum antibodies anti-E4, E7 and Ras could be used as markers for early cervical lesions associated with HPV (human papillomavirus. MATERIAL AND METHODS: A seroepidemiological case-control study was conducted between March 1999 and April 2000 at the dysplasia clinic of Hospital General Doctor Gea Gonzalez, in Mexico City, to evaluate the presence of antibodies anti-E4, E7, and Ras through a sandwich ELISA. Analysis was done using odds ratios and 95% confidence intervals. RESULTS: Anti-E7 antibodies were associated to women with CIN III lesions, while anti-E4 and Ras antibodies were strongly associated with CIN I-II lesions. The antibody profile of women with different

  1. Transferência e psicoterapia de grupo Transferencia y psicoterapia de grupo Transference and group psychotherapy

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    Luiz Paulo de C. Bechelli

    2006-02-01

    , coexisten múltiples transferencias que los miembros del grupo establecen entre sí, potencializando un gama de posibilidades de sentimientos. Ambas modalidades mantienen en común el presupuesto de que los conflictos psíquicos que impulsaron el paciente a buscar ayuda se pueden reducir o inclusive suprimir mediante la interpretación y la elaboración de la transferencia, que funcionan como procedimientos de cambio en el decurso del proceso terapéutico.This study examines the concept of transference, focusing on its peculiarities in the group context. The nature of the therapeutic situation and the broad freedom given to patients in order to access the unconscious material at their own pace, within a safe environment and with as little censorship as can be managed, transference gradually takes place. Through displacement, the psychotherapist and group members are perceived not as they are, with their real attributes, but as one or more objects that arouse emotions coming from the infant world, more precisely from the collection of deep affective influences. One peculiarity of the group situation when compared to individual psychotherapy is that, in the former, multiple transferences coexist, which group members establish among themselves, enabling a wide range of possible feelings. Both treatment modes share the assumption that unresolved conflicts which stimulated patients to seek for help can be reduced or even abolished through the interpretation and working through of transference, which functions as a process of change throughout the psychotherapy.

  2. Focus groups: técnica de investigación cualitativa en investigación de mercados

    OpenAIRE

    Ivankovich-Guillén, Carmen Isabel; Araya-Quesada, Yorleny

    2011-01-01

    Los focus groups son utilizados en investigación de mercados como una herramienta de investigación cualitativa, por la posibilidad de interactuar con el grupo meta objeto de estudio, por lo que se puede conocer y entender de manera profunda las actitudes, necesidades, intereses y motivaciones de los participantes. Los focus groups siguen el desarrollo riguroso de las etapas de investigación, que inician con el planteamiento del problema, y concluyen con la presentación oral y escrita de la in...

  3. Focus groups: técnica de investigación cualitativa en investigación de mercados

    Directory of Open Access Journals (Sweden)

    Carmen Isabel Ivankovich-Guillén

    2011-01-01

    Full Text Available Los focus groups son utilizados en investigación de mercados como una herramienta de investigación cualitativa, por la posibilidad de interactuar con el grupo meta objeto de estudio, por lo que se puede conocer y entender de manera profunda las actitudes, necesidades, intereses y motivaciones de los participantes. Los focus groups siguen el desarrollo riguroso de las etapas de investigación, que inician con el planteamiento del problema, y concluyen con la presentación oral y escrita de la investigación.

  4. Aspects of hairy black holes

    Energy Technology Data Exchange (ETDEWEB)

    Anabalón, Andrés, E-mail: andres.anabalon-at@uai.cl [Departamento de Ciencias, Facultad de Artes Liberales y Facultad de Ingeniería y Ciencias, Universidad Adolfo Ibáñez, Viña del Mar (Chile); Astefanesei, Dumitru [Instituto de Física, Pontificia Universidad Católica de Valparaíso, Casilla 4059, Valparaíso (Chile)

    2015-03-26

    We review the existence of exact hairy black holes in asymptotically flat, anti-de Sitter and de Sitter space-times. We briefly discuss the issue of stability and the charging of the black holes with a Maxwell field.

  5. Antimicrobial and anti-virulence activity of capsaicin against erythromycin-resistant, cell-invasive Group A streptococci

    Directory of Open Access Journals (Sweden)

    Emanuela eMarini

    2015-11-01

    Full Text Available Capsaicin (8-methyl-N-vanillyl-6-nonenamide is the active component of Capsicum plants (chilli peppers, which are grown as food and for medicinal purposes since ancient times, and is responsible for the pungency of their fruit. Besides its multiple pharmacological and physiological properties (pain relief, cancer prevention, and beneficial cardiovascular, and gastrointestinal effects capsaicin has recently attracted considerable attention because of its antimicrobial and anti-virulence activity. This is the first study of its in vitro antibacterial and anti-virulence activity against Streptococcus pyogenes [Group A streptococci (GAS], a major human pathogen. The test strains were previously characterized, erythromycin-susceptible (n=5 and erythromycin-resistant (n=27, cell-invasive pharyngeal isolates. The MICs of capsaicin were 64-128 μg/mL (the most common MIC was 128 µg/mL. The action of capsaicin was bactericidal, as suggested by MBC values that were equal or close to the MICs, and by early detection of dead cells in the live/dead assay. No capsaicin-resistant mutants were obtained in single-step resistance selection studies. Interestingly, growth in presence of sublethal capsaicin concentrations induced an increase in biofilm production (p ≤ 0.05 and in the number of bacteria adhering to A549 monolayers, and a reduction in cell-invasiveness and haemolytic activity (both p ≤ 0.05. Cell invasiveness fell so dramatically that a highly invasive strain became non-invasive. The dose-response relationship, characterized by opposite effects of low and high capsaicin doses, suggests a hormetic response. The present study documents that capsaicin has promising bactericidal activity against erythromycin-resistant, cell-invasive pharyngeal GAS isolates. The fact that sublethal concentrations inhibited cell invasion and reduced haemolytic activity, two important virulence traits of GAS, is also interesting, considering that cell

  6. Estudio de la respuesta autoreactiva de linfocitos B anti-periferina en la diabetes tipo I

    OpenAIRE

    Garabatos Leitón, Mª Nahir

    2014-01-01

    [spa] La diabetes tipo 1 (DT1) es una enfermedad de origen multifactorial, caracterizada por la destrucción selectiva de células ß productoras de insulina localizadas en los islotes pancreáticos. Estudios realizados en el modelo de ratón NOD, han revelado que la respuesta autoinmune en esta enfermedad está dirigida principalmente por poblaciones autoreactivas de linfocitos T CD4 y CD8 infiltrantes de islote. Durante muchos años, el papel de los linfocitos B en la DT1 ha sido relegado a un ...

  7. Desenvolvimento de formulações e tecnologia de obtenção de comprimidos revestidos de efavirenz: terapia anti-HIV Development of formulations and technology of efavirenz coated tablets obtention: anti-HIV therapy

    Directory of Open Access Journals (Sweden)

    Osnir de Sá Viana

    2006-12-01

    Full Text Available O efavirenz é uma das mais recentes classes de agentes anti-retrovirais aplicados no tratamento de infecções por HIV. Está entre os medicamentos de primeira escolha no tratamento da AIDS. Como o efavirenz possui característica hidrofóbica, baixa densidade e oferece grande resistência ao escoamento, a escolha de uma formulação adequada deste fármaco é essencial no desenvolvimento dos comprimidos e para garantir melhor disponibilização no trato gastrointestinal, de forma a alcançar a biodisponibilidade e o efeito terapêutico desejados. Neste trabalho, apresentamos, de forma lógica, o desenvolvimento tecnológico de comprimidos revestidos de efavirenz, levando em consideração suas características físicas e físico-químicas. Os núcleos (comprimidos de efavirenz foram obtidos utilizando-se a técnica de granulação por via úmida. No revestimento por película utilizou-se Opadry® Y-1-7000 em sistema aquoso. Os parâmetros adotados para avaliação física dos comprimidos seguiram as especificações farmacopéicas oficiais e a determinação quantitativa foi realizada mediante método analítico desenvolvido e validado.Efavirenz is one of the most recent classes of anti-retroviral drugs used in the treatment of HIV infections. It is the first choice therapy for AIDS treatment. As efavirenz detains hydrofobic characteristic, low density and offers great resistance to draining, it has been essential to choose an adequated formulation for it, in order to guarantee drug's availability in gastro-intestinal tract, achieving bioavailability and expected therapeutical effects. This work presents efavirez coated tablets thecnological development, considering the physics and physico-chemical characteristics of this drug. The efavirez nucleus (tablets has been obtained employing granulation technics by humid via. In the coating by film, Opadry Y-1-7000 in aquous system was used. The adopted parameters to tablet phisics evaluation

  8. Perfil de utilización de los anti-factor de necrosis tumoral en pacientes de Colombia

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    Jorge Machado

    2011-03-01

    Conclusiones. Los anti-TNF se emplearon a las dosis recomendadas, principalmente en artritis reumatoide y en combinación con otros antirreumáticos. El costo directo del tratamiento se consideró elevado para el sistema sanitario del país.

  9. Saldo zeugen iets omlaag : Animal Sciences Group heeft de langetermijnsaldo's weer berekend

    NARCIS (Netherlands)

    Animal Sciences Group (ASG),

    2009-01-01

    Animal Sciences Group (ASG) van Wageningen UR heeft in opdracht van de Productschappen Vee, Vlees en Eieren (PVE) de uitgangspunten en normen voor de bedrijfsbegrotingen voor de lange termijn vastgesteld. De begrotingsnormen worden opgenomen in Kwantitatieve Informatie Veehouderij (Kwin-V) 2009-2010

  10. Concordância na detecção de anticorpos anti-Toxoplasma gondii e anti-Neospora caninum no sangue e no leite bovino pela reação de imunofluorescência indireta

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    Andréa Christina Ferreira Meirelles

    2014-12-01

    Full Text Available O objetivo deste estudo foi avaliar a aplicabilidade da pesquisa de anticorpos anti- Toxoplasma gondii e anti- Neospora caninum em amostras de leite bovino pela reação de imunofluorescência indireta (RIFI e sua concordância com a detecção desses anticorpos em amostras de soro sanguíneo, simultaneamente coletadas das mesmas vacas. No total, foram analisadas amostras correspondentes de soro sanguíneo e de leite de 177 vacas em início de lactação. Para o T. gondii, o diagnóstico no leite demonstrou concordância boa e sensibilidade baixa, quando comparado ao soro sanguíneo com título de anticorpos séricos ≥64 (ponto de corte. Quanto ao N. caninum, obteve-se concordância excelente entre a detecção de anticorpos no soro sanguíneo com título ≥50 (considerado ponto de corte para termos de diagnóstico e no leite, com sensibilidade de 80,7% e especificidade de 100%, no entanto, para as vacas com títulos de anticorpos ≥100 no soro sanguíneo, a sensibilidade e a especificidade foram de 100%. Nas condições do presente estudo, demonstrou-se que a RIFI não é indicada para diagnóstico da toxoplasmose em amostras de leite bovino, devido ao alto percentual de vacas soropositivas para anticorpos anti-T. gondii no soro sanguíneo diluído 1:64, em cujas amostras de leite não houve detecção desses anticorpos. Por outro lado, a RIFI é um teste viável para o diagnóstico da neosporose bovina, especialmente considerando como ponto de corte um título de anticorpos séricos ≥100, podendo ser recomendável pela praticidade de coleta da amostra como parte de programas de saúde dos rebanhos e estudos epidemiológicos

  11. Meditaciones anti-cartesianas: sobre el origen del anti-discurso filosófico de la modernidad

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    ENRIQUE DUSSEL

    2008-01-01

    Full Text Available Descartes pasa por ser el primer filósofo moderno. Si se interpreta la Modernidad tal como lo hace el pensamiento decolonial o la filosofía de la liberación habría que resituar el siglo XVI, y los filósofos de ese siglo, como el origen de la filosofía moderna y no a Descartes. Además, Descartes fue alumno de los filósofos hispanos del siglo XVI contra los que se opina. El antidiscurso de la Modernidad no surge en la Ilustración sino al inicio del proceso de la conquista. Hay entonces que replantear completamente la historia filosófica de la Modernidad. Por último, la crítica de la Modernidad más radical debe buscarse en aquellos que la sufrieron como Guamán Poma de Ayala en el Perú.

  12. Arterite de Takayasu: tratamento com anti-TNF em uma casuística brasileira Takayasu arteritis: anti-TNF therapy in a Brazilian setting

    Directory of Open Access Journals (Sweden)

    Guilherme Nunes

    2010-06-01

    Full Text Available O objetivo deste estudo é descrever as características clínicas e as respostas às intervenções terapêuticas, incluindo a terapia antifator de necrose tumoral (TNF, em uma série de casos brasileiros de arterite de Takayasu (AT. Foi realizado um estudo observacional, retrospectivo, com base na revisão de prontuários, incluindo todos os pacientes com AT, de acordo com os critérios de classificação do American College of Rheumatology, em acompanhamento no Serviço de Reumatologia do Hospital Universitário da Universidade Federal de Santa Catarina (UFSC, Brasil. Foram incluídos 15 pacientes, sendo 14 (93,3% mulheres, com idade média ao diagnóstico de 29,6 anos. Hipertensão arterial sistêmica (60,0% e ausência de pulsos em membros superiores (53,3% foram os achados clínicos mais comuns ao diagnóstico. As artérias subclávias e carotídeas foram os vasos mais frequentemente acometidos. Doze pacientes (80,0% não obtiveram remissão sustentada em terapia isolada com corticosteroide, tendo sido empregada terapia imunossupressora, sendo metotrexato, azatioprina e ciclofosfamida as drogas utilizadas. Intervenções cirúrgicas foram necessárias em 53,3% dos casos. Três casos (20,0% foram refratários à terapia com corticoides e imunossupressores e foram tratados com agentes anti-TNF, com subsequente remissão da doença. Em conclusão, observou-se que uma parcela importante dos casos de AT é refratária à terapia tradicional e os agentes anti-TNF podem representar uma opção promissora para o controle da doença nesses casos.The aim of this study was to describe clinical features and response to different therapeutic interventions, including anti-tumor necrosis factor (TNF agents, in a case series of Takayasu arteritis (TA from Brazil. A retrospective observational chart-review study was performed including all patients meeting the American College of Rheumatology TA classification criteria followed at the rheumatology

  13. Prevalência de não adesão à farmacoterapia anti-hipertensiva e fatores associados

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    Mayckel da Silva Barreto

    2015-02-01

    Full Text Available Objetivo: verificar a prevalência da não adesão ao tratamento medicamentoso anti-hipertensivo e sua associação com fatores biosócio-econômicos e assistenciais. Método: pesquisa descritiva de corte transversal, realizada com 422 indivíduos hipertensos. As informações foram coletadas, por meio de entrevistas domiciliares realizadas entre dezembro de 2011 e março de 2012. Resultados: os resultados demonstraram que os entrevistados eram, em sua maioria, do sexo feminino, casados, idosos, com baixa renda familiar e pouco tempo de diagnóstico. Foram considerados não aderentes ao tratamento medicamentoso 42.65% dos participantes. Os hipertensos não brancos, com menos de oito anos de estudo, que não frequentavam as consultas médicas; utilizavam mais de duas medicações anti-hipertensivas e que não possuíam plano de saúde apresentaram maiores chances de não aderirem à farmacoterapia. Conclusão: esses achados reforçam que hipertensos com características socioeconômicas desfavoráveis e dificuldade de acesso ao serviço necessitam de intervenções diferenciadas, a fim de estimulá-los a aderirem ao tratamento medicamentoso.

  14. Detección de anticuerpos anti-Brucella spp. en cerdos mediante técnicas de aglutinación y ELISA indirecto en las provincias de Buenos Aires y La Pampa: Argentina Detection of anti-Brucella spp. antibodies in swine by agglutination techniques and indirect ELISA in the Buenos Aires and La Pampa provinces: Argentina

    OpenAIRE

    H.A. Castro; S.R. González; M.I. Prat; P.C. Baldi

    2006-01-01

    En nuestro país no existe un programa de control sobre brucelosis porcina y su verdadera situación epidemiológica es desconocida. El objetivo de nuestro trabajo fue detectar la presencia de anticuerpos anti-Brucella spp. en porcinos provenientes de criaderos del sudoeste de la provincia de Buenos Aires y del este de la provincia de La Pampa. La toma de muestras de sangre se realizó en el momento del faenado de los animales. La detección de anticuerpos se efectuó mediante las técnicas de aglut...

  15. Continuous Planetary Polar Observation from Hybrid Pole-Sitters at Venus, Earth, and Mars

    NARCIS (Netherlands)

    Heiligers, M.J.; van den Oever (student TUDelft), Tom; Ceriotti, M.; Mulligan, P.; McInnes, CR

    2017-01-01

    A pole-sitter is a satellite that is stationed along the polar axis of the Earth, or any other planet, to generate a continuous, hemispherical view of the planet’s polar regions. In order to maintain such a vantage point, a low-thrust propulsion system is required to counterbalance the gravitational

  16. Effet anti-ulcereux de l'extrait hydroalcoolique D'ecorce de tronc et ...

    African Journals Online (AJOL)

    Ficus polita (moraceae) est largement utilisee dans la medecine traditionnelle togolaise pour le traitement des affections diverses telles que les douleurs intercostales, lfinsuffisance hepatique, les hemorroides, les ulceres gastroduodenaux. Ce travail sfinscrit dans le cadre de la valorisation de plantes medicinales et de la ...

  17. Hepatites pós-transfusionais na cidade de Campinas, SP, Brasil: II. Presença dos anticorpos anti-HBc e anti-HCV em candidatos a doadores de sangue e ocorrência de hepatites pós-transfusionais pelo vírus C nos receptores de sangue ou derivados Post-transfusional hepatitis in the city of Campinas, SP, Brazil: II- Presence of anti-HBc and anti-HCV antibodies in blood donors and occurrence of post-transfusional hepatitis C virus in recipients of blood or derivates

    Directory of Open Access Journals (Sweden)

    Fernando Lopes Gonçales Júnior

    1993-02-01

    Full Text Available Pesquisamos os anticorpos anti-HBc e anti-HCV em amostras de soros provenientes de 799 candidatos a doadores, que tiveram suas unidades de sangue ou derivados transfundidas a 111 receptores. O anti-HBc e o anti-HCV foram reagentes, em respectivamente 9 e 2,1% dos doadores testados. Observamos que entre os 111 receptores, 44 haviam recebido pelo menos uma unidade anti-HBc positiva e 67 haviam sido transfundidos somente com unidades anti-HBc negativas. Houve um risco 4,5 vezes maior de aquisição de hepatite por vírus C pelos receptores que receberam pelo menos uma unidade anti-HBc positiva Se a pesquisa do anti-HBc fosse realizada na triagem sorológica dos doadores de sangue, cerca de 56% dos casos de HVC nos receptores saiam evitados. A população de receptores que recebeu pelo menos uma unidade anti-HCV reagente, apresentou um risco 29 vezes maior de adquirir esta hepatite, quando comparada aos receptores transfundidos com todas as unidades anti-HCV negativas. A realização do teste para a pesquisa do anti-HCV na triagem dos doadores de sangue, preveniria 79% dos casos de HVC pós-transfusionais. Os candidatos a doadores brasileiros parecem ser acometidos simultânea ou sequencialmente, pelos vírus B e C das hepatites, pois, 44,4% dos doadores anti-HCV positivos, também foram anti-HBc positivos. A realização dos testes para as pesquisas dos anticorpos anti-HBc e anti-HCV, nas triagens hemoterápicas, está indicada para prevenir a transmissão de hepatites pós-transfusionais, em nosso meio.We have analysed anti-HBc and anti-HCV antibodies in serum samples from 799 donors which had their blood or derivates transfused to 111 recipients. Anti-HBc and anti-HCV were reactive in respectively 9 and 2.1% of the donors tested. We have observed that among the 111 recipients, 44 had received at least one positive anti-HBc unit and 67 had been transfused only with negative anti-HBc, units. The risk of developing hepatitis C virus was 4.5 times

  18. Targeting of highly conserved Dengue virus sequences with anti-Dengue virus trans-splicing group I introns

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    Fraser Tresa S

    2010-11-01

    Full Text Available Abstract Background Dengue viruses (DENV are one of the most important viral diseases in the world with approximately 100 million infections and 200,000 deaths each year. The current lack of an approved tetravalent vaccine and ineffective insecticide control measures warrant a search for alternatives to effectively combat DENV. The trans-splicing variant of the Tetrahymena thermophila group I intron catalytic RNA, or ribozyme, is a powerful tool for post-transcriptional RNA modification. The nature of the ribozyme and the predictability with which it can be directed makes it a powerful tool for modifying RNA in nearly any cell type without the need for genome-altering gene therapy techniques or dependence on native cofactors. Results Several anti-DENV Group I trans-splicing introns (αDENV-GrpIs were designed and tested for their ability to target DENV-2 NGC genomes in situ. We have successfully targeted two different uracil bases on the positive sense genomic strand within the highly conserved 5'-3' cyclization sequence (CS region common to all serotypes of DENV with our αDENV-GrpIs. Our ribozymes have demonstrated ability to specifically trans-splice a new RNA sequence downstream of the targeted site in vitro and in transfected insect cells as analyzed by firefly luciferase and RT-PCR assays. The effectiveness of these αDENV-GrpIs to target infecting DENV genomes is also validated in transfected or transformed Aedes mosquito cell lines upon infection with unattenuated DENV-2 NGC. Conclusions Analysis shows that our αDENV-GrpIs have the ability to effectively trans-splice the DENV genome in situ. Notably, these results show that the αDENV-GrpI 9v1, designed to be active against all forms of Dengue virus, effectively targeted the DENV-2 NGC genome in a sequence specific manner. These novel αDENV-GrpI introns provide a striking alternative to other RNA based approaches for the transgenic suppression of DENV in transformed mosquito cells and

  19. Utilização de anti-inflamatórios não esteróides no tratamento de neoplasias

    OpenAIRE

    Silva, Daniela Botelho da

    2013-01-01

    Dissertação de mestrado, Ciências Farmacêuticas, Faculdade de Ciências e Tecnologia, Universidade do Algarve, 2013 Este trabalho pretende ser uma revisão exaustiva da literatura sobre o papel dos anti-inflamatórios não esteróides no tratamento de neoplasias. Os anti-inflamatórios não esteróides têm sido utilizados ao longo dos tempos para o tratamento da dor e da febre sendo que às propriedades analgésicas e anti-piréticas acrescenta-se um marcado efeito anti-inflamatório. Estas caracte...

  20. Efeito de anti-inflamatórios não esteroidais na apoptose de células epidermais lamelares de equinos com laminite

    OpenAIRE

    Gonçalves,C.A.P.; Botteon,P.T.L.; Alves,G. E.S.; Faleiros,R.R.; Paes Leme,F.O.; Mendes,H.M.F.; Vasconcelos,A.C.

    2013-01-01

    O objetivo deste trabalho foi avaliar a influência da administração dos anti-inflamatórios não esteroidais (AINEs) cetoprofeno, fenilbutazona e flunixin meglumine sobre o índice apoptótico de células epiteliais do tecido lamelar de cavalos com laminite induzida por administração de amido. Foram empregados 20 equinos hígidos, divididos em quatro grupos experimentais (n=5): solução salina, cetoprofeno, fenilbutazona e flunixin meglumine. O tecido lamelar foi coletado por biópsia, fixado e corad...

  1. El estudio del impacto de los movimientos sociales: el caso del movimiento estudiantil anti-Bolonia

    Directory of Open Access Journals (Sweden)

    Joseba Fernández González

    2014-06-01

    Full Text Available En esta artículo presentamos una introducción sobre cómo las investigaciones sobre movimientos sociales han enfocado el estudio del impacto de los movimientos sociales. Aludiremos en el primer punto a cómo la ausencia continuada de estudios sobre este asunto está justificada por las dificultades metodológicas a las que se enfrenta el investigador al determinar los impactos de los movimientos sociales. En el segundo punto, presentamos un repaso a una de las dimensiones que más preocupan a los investigadores (y activistas sobre movimientos sociales: la relación entre democracia, procesos de democratización y movimientos sociales. Finalmente, abordamos el estudio de los posibles impactos y resultados, a distintos niveles (biográficos, culturales y políticos, por parte de un movimiento concreto: el movimiento estudiantil anti-Bolonia. This article is an introduction to how social movements studies have dealt with the issue of the outcomes of social movements. Firstly, I will argue that the lack of a systematic research on the outcomes of social movements is due to methodological difficulties. Secondly, I will review one of the dimensions of social movements which has received more attention: the relationship between democracy, democratization processes and social movements. Finally, I will focus on a particular social movement (the student movement against the Bolonia Process in order to analyse the main possible outcomes of this movement at the biographical, cultural and political levels.

  2. MÉTODO DE ESCOLHA DE MEDICAMENTOS ANTI-HIPERTENSIVOS POR GESTORES DA ÁREA DE SAÚDE

    Directory of Open Access Journals (Sweden)

    Rondinelli de Carvalho LADEIRA

    2016-06-01

    Full Text Available Um problema enfrentado pelos gestores de saúde é a aquisição de medicamentos que, para o abastecimento do SUS, deve-se levar em consideração a efetividade, os custos e a segurança dos mesmos. A análise farmacoeconômica pode ser vista como a descrição e a análise dos custos da terapia farmacêutica para os sistemas de assistência à saúde e para a sociedade. O presente trabalho faz a análise de custo-efetividade de cinco betabloqueadores adrenérgicos usados no tratamento de hipertensão arterial (atenolol, carvedilol, metoprolol, propranolol e sotalol através de auxílio multicritério à decisão. Tendo em vista gestores de saúde como agentes da decisão, foram testados os métodos de Borda para definição dos pesos dos critérios por especialistas e AHP para escolha do medicamento através do software IPE 1.0. Questionários foram aplicados a sete profissionais médicos especialistas em cardiologia para a comparação dos critérios (efetividade, custo, experiência com o fármaco e segurança, sub-critérios (agravamento da insuficiência cardíaca congestiva, agravamento da doença arterial periférica, broncoespasmo, bradicardia e alterações metabólicas, relativos ao critério segurança e alternativas à luz dos critérios estudados. O betabloqueador que se apresentou como melhor escolha foi o atenolol (32,38%.

  3. Pesquisa de anticorpos anti-"Brucella canis" em cães provenientes da região metropolitana de salvador

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    Adriano Costa Alcantara

    2007-03-01

    Full Text Available A brucelose canina por Brucella canis é uma doença infecto-contagiosa caracterizada principalmente por abortamentos e esterilidade nas fêmeas bem como orquite e epididimite nos machos. Além da grande importância econômica para criadores de cães, o caráter zoonótico da brucelose canina também deve ser considerado em virtude da complexa relação da população canina com os seres humanos. Deste modo, com o objetivo de pesquisar anticorpos anti Brucella canis em cães residentes na região metropolitana de Salvador, foram avaliadas 85 amostras de soro sanguíneo de cães domiciliados, machos e fêmeas, de idade e raças variadas através da técnica de imunodifusão em gel de agarose, com antígeno de membrana de Brucella ovis desenvolvido pelo Centro de Pesquisa Veterinária Desidério Finamor-RS (CPVDF. Os resultados encontrados indicaram uma soropositividade de 5,88% (5/85, demonstrando a presença de anticorpos anti-Brucella canis em cães residentes na região metropolitana de Salvador salientando a importância de maiores estudos desta zoonose.

  4. Desarrollo de superficies modificadas oro - anticuerpo anti-PSPB para su uso como biosensor en la detección de preñez bovina

    Directory of Open Access Journals (Sweden)

    Justo Laíz

    2011-05-01

    Full Text Available En este trabajo se presentan los resultados preliminares para el desarrollo de un biosensor amperométrico destinado a la cuantificación de Proteína B Específica de la Preñez (PSPB en fluidos biológicos como medio de diagnóstico clínico precoz de la preñez bovina. A la superficie de oro modificada con ácido mercaptoundecanoico (MUA se fijaron anticuerpos anti-PSPB y peroxidasa de rábano (HRP. Se verificó la inmovilización de las biomoléculas mediante voltamperometría cíclica y medida del ángulo de contacto.Se estudió el comportamiento electroquímico del electrodo desarrollado por medio de voltamperometría cíclica y medidas a potencial constante, estableciendo la relación entre el cambio de corriente catódica (al potencial de reducción de la quinona y la concentración de PSPB. Esta relación se ve afectada por la formación de complejos antígeno – anticuerpo que limitan el acceso del sustrato al sitio activo de la enzima, provocando una disminución en la señal eléctrica.El electrodo modificado de oro - anti-PSPB – HRP respondió de forma inversamente proporcional a la concentración de PSPB a un potencial de -200 mV (contra electrodo de referencia Ag/AgCl, tanto por voltamperometría cíclica como a potencial constante, y por tanto podría ser la base para el desarrollo de un biosensor amperométrico para detectar precozmente la preñez bovina.

  5. Anti-Adhesive Activities of Flavan-3-ols and Proanthocyanidins in the Interaction of Group A-Streptococci and Human Epithelial Cells

    Directory of Open Access Journals (Sweden)

    Aneta Janecki

    2010-10-01

    Full Text Available Bacterial adhesion to epithelial cells is a key step in infections, allowing subsequent colonization, invasion and internalization of pathogens into tissues. Anti-adhesive agents are therefore potential prophylactic tools against bacterial infections. The range of anti-adhesive compounds is largely confined to carbohydrate analogues. Tannins are generously recognized as potent antimicrobials, but little data exist on their anti-adherence potency. Using a model for mucosal pathogenesis with labeled group A-streptococci (GAS and human laryngeal HEp-2 cells, a series of flavan-3-ols (epicatechin, epigallocatechin, epigallocatechin-3-O-gallate and highly purified and chemically characterized proanthocyanidin samples including procyanidins based on epicatechin, catechin or ‘mixed’ constituent flavanyl units, prodelphinidins made up of (epigallocatechin monomeric unts as well as oligomers possessing A-type units in their molecules was evaluated for anti-adhesive effects. Reduced microbial adherence was observed exclusively for prodelphinidins, suggesting that pyrogallol-type elements, i.e., (epigallocatechin units are important structural features. This is the first report on structure-activity relationships regarding the anti-adhesive potency of proanthocyanidins. In addition, the structures of the first chemically defined proanthocyanidins from Pelargonium sidoides are disclosed.

  6. As representações sociais de pacientes em ínicio de terapia anti-retroviral envolvidas na adesão ao tratamento

    OpenAIRE

    Angela de Cassia Rover da Silva

    2006-01-01

    Neste estudo, buscou-se compreender as representações sociais de portadores do vírus HIV, ou da aids, sobre os aspectos que se relacionam à adesão à terapia anti-retroviral. Foram analisadas 30 entrevistas abertas, realizadas com pacientes em início de terapia anti-retroviral, atendidos em dois serviços de referência em Belo Horizonte, Minas Gerais. Na análise, explicitaram-se as categorias relacionadas à adesão, que compõem dois grandes grupos. O primeiro inclui os aspectos relacionados à ex...

  7. Meditaciones anti-cartesianas: sobre el origen del anti-discurso filosófico de la modernidad

    OpenAIRE

    ENRIQUE DUSSEL

    2008-01-01

    Descartes pasa por ser el primer filósofo moderno. Si se interpreta la Modernidad tal como lo hace el pensamiento decolonial o la filosofía de la liberación habría que resituar el siglo XVI, y los filósofos de ese siglo, como el origen de la filosofía moderna y no a Descartes. Además, Descartes fue alumno de los filósofos hispanos del siglo XVI contra los que se opina. El antidiscurso de la Modernidad no surge en la Ilustración sino al inicio del proceso de la conquista. Hay entonces que repl...

  8. The impact of anti hypertensive drug groups on urinary albumin excretion in a non-diabetic population

    NARCIS (Netherlands)

    Monster, TBM; Janssen, WMT; de Jong, PE; de Jong-van den Berg, LTW

    Aims Microalbuminuria (30-300 mg 24 h(-1)) is recognized to be independently associated with renal and cardiovascular risk. Antihypertensives may lower microalbuminuria. We questioned whether the use of different anti hypertensive drug classes in general practice influences microalbuminuria as

  9. Gestion de la douleur chronique par les infirmières des Groupes de médecine de famille

    Science.gov (United States)

    Bergeron, Dave A; Bourgault, Patricia; Gallagher, Frances

    2015-01-01

    INTRODUCTION : Des milliers de personnes souffrent actuellement de douleur chronique (DC) pour laquelle la prise en charge s’avère souvent inadéquate. Au Québec, les infirmières qui oeuvrent dans les Groupes de médecine de famille (GMF) jouent un rôle clé dans le suivi des personnes aux prises avec des problèmes de santé chroniques dont la DC. OBJECTIFS : Cette étude a pour objectifs de décrire les activités réalisées par les infirmières œuvrant en GMF en lien avec la gestion de la douleur chez la clientèle souffrant de DC, ainsi que les barrières à ces activités. MÉTHODE : Un dispositif descriptif corrélationnel transversal de type enquête postale a été utilisé. La population accessible à l’étude comprend les infirmières qui figurent sur la liste des membres de l’Ordre des infirmières et infirmiers du Québec travaillant en GMF. L’ensemble des infirmières figurant sur cette liste ayant consenti à être contactées à leur domicile pour des fins de recherche ont été contactées. Un questionnaire postal auto-administré (Pain Management Activities Questionnaire) a été complété par 53 infirmières travaillant en GMF. RÉSULTATS : Les trois activités le plus souvent réalisées par les infirmières sont d’établir une relation thérapeutique avec le client; de discuter avec le médecin de l’efficacité des mesures thérapeutiques et de faire un enseignement personnalisé au client. Les infirmières ont la perception qu’elles rencontrent en moyenne 2,68 personnes par semaine qui souffrent de DC. La méconnaissance des interventions possibles en douleur (71,7%) et la non-disponibilité de l’information sur la gestion de la douleur (52,8%) constituent les principales barrières selon les infirmières sondées. CONCLUSION : Les infirmières au sein des GMF font actuellement peu d’activités en gestion de la DC probablement en raison du manque de reconnaissance de la DC. PMID:25848847

  10. Adesão ao tratamento farmacológico anti-hipertensivo de pacientes em hemodiálise

    Directory of Open Access Journals (Sweden)

    Paulo Roberto da Silva Ribeiro

    2015-10-01

    Full Text Available O risco de morbidade/mortalidade por doenças cardiovasculares em pacientes com doença renal crônica (DRC é elevado, sendo imprescindível a instituição de uma terapia anti-hipertensiva eficaz. A baixa adesão ou não adesão ao tratamento farmacológico anti-hipertensivo prejudica o alcance dos resultados terapêuticos no retardo da progressão da DRC. Objetivou-se estudar a adesão à terapia anti-hipertensiva em 120 pacientes com DRC em hemodiálise. Trata-se de um estudo transversal, descritivo, com abordagem quantitativa, realizado entre maio a junho de 2011 na Clínica de Doenças Renais de Imperatriz – MA. Os dados foram obtidos através da análise dos prontuários dos pacientes e da aplicação de roteiro de entrevista para a coleta de dados sociodemográficos, clínicos e relacionados ao tratamento medicamentoso anti-hipertensivo. O nível de adesão ao tratamento foi estimado pelo Teste de Morisky- Green. A maioria dos pacientes é do sexo masculino (69,2%, possui idade inferior a 60 anos (69,2%, é analfabeta ou possui apenas o ensino fundamental (79,2% e possui baixa renda mensal (90,8%. A hipertensão arterial foi a doença de base prevalente. Houve predomínio da politerapia em 78,3% dos casos. Os betabloqueadores foram os anti-hipertensivos mais utilizados, seguidos pelos bloqueadores dos canais de cálcio e agentes que atuam no sistema renina-angiotensina. O Teste de Morisky-Green apontou que 58,3% dos entrevistados apresentaram nível elevado de adesão à terapia medicamentosa. A falta de acesso aos medicamentos foi o principal motivo relatado pelos pacientes para não seguirem adequadamente o tratamento anti-hipertensivo. Verificou-se a necessidade de melhorias na assistência farmacêutica a estes pacientes e a implementação de estratégias para aumentar a adesão ao tratamento.Palavras-chave: Adesão à medicação. Anti-hipertensivos. Insuficiência Renal Crônica. Diálise Renal. Farmac

  11. Freqüência de indivíduos com anticorpos sericos anti-Cysticercus cellulosae em cinco Municípios do Estado de São Paulo

    Directory of Open Access Journals (Sweden)

    Adelaide José Vaz

    1990-06-01

    Full Text Available Considerando a importância da cisticercose humana em Saúde Pública, foi estudada a freqüência de positividade da detecção de anticorpos anti-Cysticercus cellulosae em 1.264 amostras de soro, assim distribuídas: Grupol-1.064 de indivíduos da população geral (821 adultos e 243 crianças residentes em cinco municípios do Estado de São Paulo (São Paulo, Presidente Prudente, Santos, Campinas e Marília, Brasil; Grupo 11-200 de pacientes adultos internados em hospital psiquiátrico (Presidente Prudente. Para a pesquisa dos anticorpos séricos foi empregado o teste ELISA utilizando como suporte discos de tecido-resina. No Grupo I foram encontrados 18 (2,30% soros reagentes entre as amostras de adultos, e 2 (0,82% entre as das crianças; entre os doentes psiquiátricos, Grupo II, a freqüência de positividade foi de 5 %, significativamente maior (p Considering the important health public problem that human cysticercosis represents, the frequency of anti-Cysticercus cellulosae antibodies was studied in 1,264 serum samples, 1,064 being from the general population individuals (821 adults and 243 children living in five municipalities of São Paulo State, Brazil; and 200 from patients admitted to the Psychiatric Hospital Bezerra de Menezes (Presidente Prudente. Discs of synthetic fabric-resin with the Among the sera from adults, nineteen (2,30% were valently bound were employed for ELISA tests. Among the sera from adults, mineteen (2.30% were reactive 2 (0.82% among the childrens sera. Ten (5.00% among the psychiatric patients sera presented reactivity. This was significantly higher than that observed for the adults of the general population group (p < 0.05.

  12. Outcome after a dose "de-intensification" strategy with anti-TNF drugs in patients with Crohn's disease.

    Science.gov (United States)

    Chaparro, María; Barreiro-de Acosta, Manuel; García-Planella, Esther; Domènech, Eugeni; Bermejo, Fernando; Calvet, Xavier; Martín Arranz, María Dolores; Monfort, David; Gisbert, Javier P

    2016-04-01

    Dose "intensification" is a recommended strategy to recover therapeutic benefit in Crohn's disease (CD) patients who have lost initial response to anti-TNF therapy. Once patients have achieved remission, dose "de-intensification" can be used for cost and safety reasons. The primary aim of this study was to evaluate the long-term durability of remission after stepping down anti-TNF therapy. The secondary aim was to identify predictive factors associated with loss of response after "de-intensification" and to evaluate the effectiveness of a second "re-intensification" in patients who lost response after the treatment was stepped down. We evaluated CD patients who received at least one standard anti-TNF dosage after achieving remission with "intensified" anti-TNF therapy. Twenty-four patients were included. The treatment was "intensified" because of partial response in 11 patients, loss of response in 10, and primary lack of response in 3. Eight of the 24 patients had lost response after a median follow-up of only 7 months after "de-intensification" of the anti-TNF therapy. The anti-TNF drug was "intensified" again in all 8 patients. Three patients did not respond to the new "intensification", two had partial response and three achieved remission. On univariate analysis, no predictive factors were identified for loss of response after treatment "de-intensification". After only 7 months of follow-up, one-third of the CD patients who received "de-intensification" therapy lost response; of these, two-thirds did not achieve response after subsequent "re-intensification". Copyright © 2015 Elsevier España, S.L.U. and AEEH y AEG. All rights reserved.

  13. Efecto anti-Trypanosoma cruzi del aceite esencial de Cymbopogon citratus (DC Stapf (hierba luisa en ratones Balb/c

    Directory of Open Access Journals (Sweden)

    Juan Rojas

    2012-01-01

    Full Text Available Objetivo: Determinar la actividad anti-Trypanosoma cruzi in vivo del aceite esencial de Cymbopogon citratus en ratones Balb/c. Diseño: Estudio experimental, prospectivo. Institución: Instituto de Investigaciones Clínicas e Instituto de Medicina Tropical de la Facultad de Medicina de la Universidad Nacional Mayor de San Marcos, Lima, Perú. Material biológico: Aceite esencial de Cymbopogon citratus; ratones albinos Balb/c. Intervenciones: Los animales fueron asignados aleatoriamente a seis grupos de 15 ratones cada uno: infectados y no tratados (G1, infectados y tratados con benznidazol 100 mg/kg (G2, infectados y tratados con aceite esencial de Cymbopogon citratus 100 mg/kg y 250 mg/kg (G3 y G4, respectivamente, no infectados y no tratados (G5, y no infectados y tratados con 250 mg de Cymbopogon citratus (G6. La infección con T. cruzi se realizó con 10(4 trypomastigotes sanguíneos y el tratamiento empezó en el 8º día post infección (dpi hasta el 28° dpi. La parasitemia se determinó con microscopia óptica cada dos días en 5 µL de sangre de la cola. En el 14°, 21° y 28° dpi, cinco animales de cada grupo fueron sacrificados y se removió el corazón para estudio histopatológico. Principales medidas de resultados: Parasitemia, número de nidos de amastigotes e infiltrados inflamatorios. Resultados: El aceite esencial de Cymbopogon citratus 250 mg/kg/día produjo una reducción significativa en el pico de parasitemia desde 113,92 ± 25,66 hasta 74,60 ± 12,37 tripomastigotes/mL (p < 0,05. Con 100 mg/kg/día se produjo una reducción hasta 77,40 ± 14,93 tripomastigotes/ mL (p < 0,05. También redujo el número de amastigotes y de infiltrados inflamatorios en el corazón. Conclusiones: El aceite esencial de Cymbopogon citratus tuvo efecto anti-Trypanosoma cruzi en ratones Balb/c en lo referente a la disminución de la parasitemia, el número de nidos de amastigotes y los resultados inflamatorios.

  14. Efeito de anti-inflamatórios não esteroidais na apoptose de células epidermais lamelares de equinos com laminite

    Directory of Open Access Journals (Sweden)

    C.A.P. Gonçalves

    2013-10-01

    Full Text Available O objetivo deste trabalho foi avaliar a influência da administração dos anti-inflamatórios não esteroidais (AINEs cetoprofeno, fenilbutazona e flunixin meglumine sobre o índice apoptótico de células epiteliais do tecido lamelar de cavalos com laminite induzida por administração de amido. Foram empregados 20 equinos hígidos, divididos em quatro grupos experimentais (n=5: solução salina, cetoprofeno, fenilbutazona e flunixin meglumine. O tecido lamelar foi coletado por biópsia, fixado e corado pela técnica de TUNEL. À marcação positiva por essa técnica adicionou-se a avaliação morfológica celular para identificação da apoptose. Não houve diferença significativa no índice apoptótico entre os grupos tratados com anti-inflamatórios e o controle (P>0,05. Os anti-inflamatórios não interferiram sobre o índice apoptótico possivelmente porque foram administrados após a fase prodrômica da laminite e/ou porque não são eficazes em alterar a dinâmica da apoptose. Concluiu-se que a administração de anti-inflamatórios não esteroidais após a fase prodrômica da laminite não contribui para uma intervenção no curso da apoptose no tecido lamelar de cavalos com laminite quando comparados ao grupo controle não tratado. Outros estudos, com diferentes períodos de avaliação, são necessários para esclarecer os efeitos dos anti-inflamatórios não esteroidais na fisiopatologia da laminite em equinos, especialmente no que concerne à participação da apoptose.

  15. Introducción al sistema Anti-corrupción de la República Popular China.

    OpenAIRE

    Wang, Shizhou

    2011-01-01

    El objetivo de este artículo es analizar los principales instrumentos que el Derecho penal chino ha utilizado en su lucha contra la corrupción. En esta línea, se destaca cómo, en los últimos tiempos, el Partido Comunista chino ha tomado conciencia de la importancia de este fenómeno y cómo ha decido afrontarlo respondiendo a las exigencias del Derecho internacional, tratando de construir un Derecho penal anti-corrupción menos severo, pero también más eficaz en la lucha contra la peligroso fenóm...

  16. Comparison of agglutinating and neutralizing antibodies to serovar hardjo in sows immunized with two commercial whole culture polivalent anti-leptospira bacterins Comparação de anticorpos aglutinantes e neutralizantes do sorovar hardjo em fêmeas suínas imunizadas com duas bacterinas anti- leptospira comerciais

    Directory of Open Access Journals (Sweden)

    Francisco Rafael Martins Soto

    2008-09-01

    Full Text Available It was performed the comparison of the intensity and duration of agglutinating and neutralizing antibodies to serovar Hardjo in swines vaccinated with two commercial anti-leptospira bacterins. Sows no reactive to 24 Leptospira sp serovars in the microscopic agglutination test (MAT were divided in three groups: Group A (n=08: received two vaccine A doses with 30 days interval, Group B (n=08 two vaccine B doses with 30 days interval and Group C (n=08: control no vaccinated against leptospirosis.Blood samples were collected each 30 days during six months following the first vaccination. The sera were tested by MAT and growth inhibition test (GIT to serovar Hardjo in order to evaluate respectively agglutinating and neutralizing antibodies. It was found that neutralizing antibodies persisted for a longer time than the agglutinating ones and that the absence of agglutinating antibodies does not means in the absence of the neutralizing. The peaks of agglutinating antibodies was obtained at least 30 days earlier than that produced by neutralizing. The duration of both kinds of antibodies measured differed between the two bacterines tested. The period for inducing neutralizing antibodies against serovar Hardjo indicated that gilts must be immunized with two doses of whole culture anti-leptospira bacterines applied 30 days each other at least 90 days before the first mating. For the maintenance of hight levels of neutralizing antibodies the revaccinations must be performed every six months after the first vaccination.Foi efetuada a comparação entre a intensidade e duração dos níveis de anticorpos neutralizantes e aglutinantes para o sorovar Hardjo em fêmeas suínas vacinadas com duas bacterinas comerciais anti-leptospirose. Animais caracterizados como não reatores para 24 sorovares de Leptospira sp pelo teste de soroaglutinação microscópica (SAM e que nunca haviam sido vacinados contra a leptospirose foram divididos em três grupos: grupo A (n

  17. Anti-plasmodial action of de novo-designed, cationic, lysine-branched, amphipathic, helical peptides

    Directory of Open Access Journals (Sweden)

    Kaushik Naveen K

    2012-08-01

    Full Text Available Abstract Background A lack of vaccine and rampant drug resistance demands new anti-malarials. Methods In vitro blood stage anti-plasmodial properties of several de novo-designed, chemically synthesized, cationic, amphipathic, helical, antibiotic peptides were examined against Plasmodium falciparum using SYBR Green assay. Mechanistic details of anti-plasmodial action were examined by optical/fluorescence microscopy and FACS analysis. Results Unlike the monomeric decapeptides {(Ac-GXRKXHKXWA-NH2 (X = F,ΔF (Fm, ΔFm IC50 >100 μM}, the lysine-branched,dimeric versions showed far greater potency {IC50 (μM Fd 1.5 , ΔFd 1.39}. The more helical and proteolytically stable ΔFd was studied for mechanistic details. ΔFq, a K-K2 dendrimer of ΔFm and (ΔFm2 a linear dimer of ΔFm showed IC50 (μM of 0.25 and 2.4 respectively. The healthy/infected red cell selectivity indices were >35 (ΔFd, >20 (ΔFm2 and 10 (ΔFq. FITC-ΔFd showed rapid and selective accumulation in parasitized red cells. Overlaying DAPI and FITC florescence suggested that ΔFd binds DNA. Trophozoites and schizonts incubated with ΔFd (2.5 μM egressed anomalously and Band-3 immunostaining revealed them not to be associated with RBC membrane. Prematurely egressed merozoites from peptide-treated cultures were found to be invasion incompetent. Conclusion Good selectivity (>35, good resistance index (1.1 and low cytotoxicity indicate the promise of ΔFd against malaria.

  18. Effects of the basic fibroblast growth factor and its anti-factor in the healing and collagen maturation of infected skin wound Efeitos do fator de crescimento de fibroblastos básico e do seu anti-fator na cicatrização e maturação do colágeno de feridas infectadas de pele

    Directory of Open Access Journals (Sweden)

    Antonio Medeiros Dantas Filho

    2007-01-01

    Full Text Available PURPOSE: The infection is one of the main factors that affect the physiological evolution of the surgical wounds. The aim of this work is to evaluate the effects of fibroblast growth factor (FGFâ and anti-FGFâ in the healing, synthesis and maturation of collagen when topically used on infected skin wounds of rats. METHODS: An experimental study was perfomed in 60 male Wistar rats. All animals were divided in two groups (A and B. Each group was divided in three subgroups A1, B1; A2, B2 and A3, B3. After anesthesia with pentobarbital, two open squared wounds (1cm², 4cm distant to each other, were done in the dorsal skin of all the rats. In group A (n=30 the wounds were contaminated with multibacterial standard solution, and in group B(n=30 the wounds were maintained sterile. These wounds were named F1 (for inflammation analysis and F2 (for collagen study. The open wounds of A1 and B1 rats were topically treated with saline solution, A2 and B2 were treated with FGFâ and subgroups A3 and B3 were treated with FGFâ and anti-FGFâ. The rats were observed until complete epitelization of F2 wounds for determination of healing time and the expression of types I and III collagen, using Picro Sirius Red staining. Inflammatory reaction in F1 wounds was studied using hematoxilineosin staining. The three variable was measured by the Image Pro-Plus Média Cybernetics software. The statistical analysis was performed by ANOVA and Tukey test, considering pOBJETIVO: Avaliar os efeitos do fator de crescimento de fibroblastos básico (FCFâ e do anti-FCFâ na cicatrização e maturação do colágeno em feridas infectadas na pele de ratos. MÉTODOS: Um estudo experimental foi realizado em 60 ratos Wistar, divididos em dois grupos (A e B. Cada grupo foi divididos em 03 subgrupos A1,B1; A2,B2 e A3,B3. Após anestesia com pentobarbital sódico intraperitoneal, foram feitas duas feridas abertas de 1cm² na pele no dorso distando 4cm uma da outra. Essas feridas foram

  19. Pesquisa de anticorpos anti Toxoplasma gondii em fluidos intra-oculares (humor vítreo e humor aquoso) de pacientes com toxoplasmose ocular, na cidade de Belém, PA

    OpenAIRE

    Carmo,Ediclei Lima do; Almeida,Edmundo Frota; Bichara,Cléa Nazaré; Póvoa,Marinete Marins

    2005-01-01

    Foi realizada pesquisa de anticorpos IgG, IgM e IgA anti-Toxoplasma gondii no soro e fluidos intra-oculares (humor aquoso e vítreo) de pacientes com toxoplasmose ocular. A partir dos resultados obtidos verificou-se que anticorpos IgG e IgA intraocular anti-Toxoplasma gondii podem vir a ser importantes marcadores no diagnóstico de toxoplasmose ocular.

  20. Prevalência de anticorpos anti - Toxoplasma gondii em avestruzes (Struthio camelus de criatórios comerciais no estado de São Paulo

    Directory of Open Access Journals (Sweden)

    Ana Paula Angelucci Contente

    2009-06-01

    Full Text Available A toxoplasmose é uma zoonose cosmopolita causada pelo protozoário Toxoplasma gondii, podendo acometer mamíferos e aves. O presente estudo teve como objetivo estimar a prevalência do Toxoplasma gondii em avestruzes (Struthio camelus de criatórios comerciais do estado de São Paulo, como forma de auxiliar no conhecimento do comportamento e importância do parasito nesta espécie animal. Foram colhidas 195 amostras de soro de avestruzes, provenientes de Sorocaba, Campinas, São Carlos, Araçatuba, São Paulo, Vale do Ribeira, Botucatu e São José do Rio Preto, estado de São Paulo. As amostras foram analisadas pela Técnica de Aglutinação Direta Modificada (MAT, para a pesquisa de anticorpos anti - Toxoplasma gondii. Os exames sorológicos revelaram 14,36% de animais sororreagentes ao T. gondii. A titulação mínima considerada foi a diluição maior ou igual a 1:16, e a maior diluição encontrada foi 1:16384. Não foi constatada diferença significativa entre os sexos. Apenas duas regiões (São Paulo e São José do Rio Preto não apresentaram animais sororreagentes. Esses resultados salientam a importância de um estudo mais aprofundado sobre a infecção em avestruzes, e também sobre as práticas de manejo que venham a minimizar o risco de transmissão da toxoplasmose para essas aves e, por conseqüência, para o consumidor final.

  1. Pesquisa de anticorpos IgM anti-Toxoplasma gondii por meio de técnica imunoenzimática reversa

    Directory of Open Access Journals (Sweden)

    José Roberto Mineo

    1986-02-01

    Full Text Available Um teste imunoenzimático reverso foi padronizado utilizando-se como fase sólida, microplacas de polivinil sensibilizadas com anticorpos anti-IgM.7 Estas foram incubadas seqüencialmente com alíquotas de soros de pacientes com suspeita de toxoplasmose aguda, antígeno solúvel de Toxoplasma gondii, conjugado peroxidase F (ab'2 anti-toxoplasma e substrato enzimático. A atividade enzimática foi determinada por leitura espectrofotométrica, considerando-se como títulos dos soros a máxima diluição fornecendo valores de absorbância maiores que os obtidos com a menor diluição do soro padrão não-reativo. Em 69 amostras de soros de pacientes com toxoplasmose aguda, a média geométrica dos títulos no teste ELISA-Reverso IgM foi superior à de todos os outros testes para anticorpos IgM, não se observando resultados negativos falsos devidos a altos títulos de IgG específica. Não foi encontrada, também, reatividade cruzada em nenhuma das 104 amostras de soros de pacientes com outras patologias, inclusive em amostras contendo fator reumatóide IgM.

  2. Successful ABO-Incompatible Renal Transplantation:  Blood Group A1B Donor Into A2B Recipient With Anti-A1 Isoagglutinins.

    Science.gov (United States)

    Fadeyi, Emmanuel A; Stratta, Robert J; Farney, Alan C; Pomper, Gregory J

    2016-08-01

    Transplantation of the blood group A2B in a recipient was successfully performed in the setting of receiving a deceased donor kidney from an "incompatible" A1B donor. The donor and recipient were both typed for ABO blood group, including ABO genotyping. The donor and recipient were tested for ABO, non-ABO, and human leukocyte antigen (HLA) antibodies. The donor and recipient were typed for HLA antigens, including T- and B-flow cytometry crossmatch tests. The recipient's RBCs were negative with A1 lectin, and immunoglobulin G anti-A1 was demonstrated in the recipient's plasma. The donor-recipient pair was a four-antigen HLA mismatch, but final T- and B-flow cytometry crossmatch tests were compatible. The transplant procedure was uneventful; the patient experienced immediate graft function with no episodes of rejection or readmissions more than 2 years later. It may be safe to transplant across the A1/A2 blood group AB mismatch barrier in the setting of low titer anti-A1 isoagglutinins without the need for pretransplant desensitization even if the antibody produced reacts with anti-human globulin. © American Society for Clinical Pathology, 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  3. Psicoterapia de grupo de alcoólatras e de suas esposas Group psychotherapy of alcoholics and their wives

    Directory of Open Access Journals (Sweden)

    Guido Hetem

    1969-03-01

    Full Text Available São referidos os resultados obtidos com psicoterapia de grupo de 11 alcoólatras e suas esposas, separadamente. Dois grupos de 6 e 5 alcoólatras foram tratados durante 6 a 4 meses respectivamente; simultâneamente foram tratados grupos de suas respectivas esposas durante 18 a 11 meses, respectivamente. Para cada grupo foi feita uma reunião por semana, de uma hora de duração nos 8 meses iniciais e, a seguir, uma reunião cada duas semanas. Em todos os casos, os pacientes já eram alcoólatras antes de se casarem. No grupo de alcoólatras o autor assumia uma atitude paternal, protetora e compreensiva, fornecendo todos os medicamentos necessários; no grupo das esposas sua atitude era sobretudo analítica. Os resultados foram ótimos, bons ou regulares em 8 alcoólatras (72%, após 2 e 3 anos de seguimento. O tratamento foi bem aceito tanto pelos alcoólatras quanto por suas esposas. Os melhores resultados foram obtidos com os pacientes cujas esposas melhoraram nitidamente de seus conflitos pessoais e modificaram suas condutas em relação aos hábitos dos maridos.The experience with group psychoterapy treatment of 11 alcoholic patients (two groups of 6 and 5 patients treated during 6 and 4 months respectively is reported. Simultaneously their wives, identicaly grouped, have been treated during 18 and 11 months respectively. Each group had a week session lasting an hour during the first 8 months and every two weeks afterwards. All patients have been know to be alcoholics before marriage. In the alcoholic group the author mantained a paternal disposition, protective and comprehensive, giving all drug support; as far as concern their wives the author's position was mainly analytical. After a two or three years follow-up 8 alcoholics have had regular, good or excellent results (72%. Group psychoterapy treatment has been well taken by alcoholic patients as well as their wives. The treatment of alcoholic's wives was very important, the best results

  4. Histamina, receptores de histamina e anti-histamínicos: novos conceitos Histamine, histamine receptors and antihistamines: new concepts

    Directory of Open Access Journals (Sweden)

    Paulo Ricardo Criado

    2010-04-01

    Full Text Available As drogas com ação anti-histamínica estão entre as medicações mais comumente prescritas na prática dermatológica diária, tanto em adultos como em crianças. Este artigo aborda os novos conceitos da função dos receptores de histamina (receptores H1 e discute os efeitos anti-inflamatórios dessas drogas. A segunda geração de anti-histamínicos difere da primeira geração devido a sua elevada especificidade e afinidade pelos receptores H1 periféricos e devido a seu menor efeito no sistema nervoso central, tendo como resultado menores efeitos sedativos. Embora a eficácia dos diferentes anti-histamínicos H1 (anti-H1 no tratamento de doentes alérgicos seja similar, mesmo quando se comparam anti-H1 de primeira e de segunda geração, eles são muito diferentes em termos de estrutura química, farmacologia e propriedades tóxicas. Consequentemente o conhecimento de suas características farmacocinéticas e farmacodinâmicas é importante para a melhor prática médica, especialmente em gestantes, crianças, idosos e doentes com comorbidades.Drugs with antihistamine action are the most commonly prescribed medication in daily dermatologic practice, both to adults and children. This article addresses new concepts of the role of histamine receptors (H1 receptors and discusses the anti-inflammatory effects of these drugs. Second generation antihistamines differs from first generation because of their high specificity and affinity for peripheral H1-receptors. Second generation antihistamines are also less likely to produce sedation because they have less effect on the central nervous system. Although the efficacy of the various H1-antihistamines in the treatment of allergic patients is similar, even when comparing first- and second-generation drugs, these drugs are still very different in terms of their chemical structure, pharmacology and toxic properties. Consequently, knowledge of their pharmacokinetic and pharmacodynamic characteristics

  5. Design of attitude solution algorithm for tail-sitter VTOL UAV

    Directory of Open Access Journals (Sweden)

    Donghui LIU

    2016-02-01

    Full Text Available The tail-sitter Vertical Takeoff and Landing (VTOL Unmanned Aerial Vehicle(UAV, flying in a fixed-wing model, overcomes many shortcomings of traditional fixed-wing UAVs, and inherits the advantage of high overall efficiency, which means it has great development potential and very broad application prospects. The attitude of tail-sitter VTOL UAV shows a wide change range in its takeoff and landing stages, and when the attitude sensor changes more than 90 degrees in pitch direction, the Euler angles converted by the Quaternions will have singular points, which means gimbal deadlock appears. From the solution algorithm, this paper provides a method of changing the order of rotation to avoid the appearance of singular points. The results show that this method can be well applied to the attitude solution of the VTOL UAV.

  6. Transformation a Echelle Fixe et Groupe de Renormalisation pour les Objets Fractals et Multifractals

    Science.gov (United States)

    Tremblay, Real

    Dans un premier temps, la description mathematique des fractals et des multifractais est resumee. Une description de quelques-uns des principaux systemes ou apparaissent des spectres d'exposants multifractals est presentee. L'accent est mis sur deux archetypes, le modele de percolation et le modele de rupture dielectrique. Un modele original de cascade multifractale avec interactions inspire des modeles phenomenologiques de la turbulence est presente et son spectre d'exposants calcule analytiquement. Ce travail elargit la classe de modeles pour lesquels on connait le spectre d'exposants exactement. Dans la seconde partie, on trouve une analyse critique de la transformation a echelle fixe. Sont discutees plus particulierement les proprietes que doivent posseder les diagrammes de base pour obtenir une transformation invariante d'echelle. Les differentes hypotheses arbitraires de la theorie sont mises en evidence. L'une de ces hypotheses concerne le traitement auto-coherent des conditions aux frontieres. Considerant cette hypothese comme valable, la theorie utilise la distribution de trous dans un ensemble de Cantor aleatoire. Un calcul exact de cette distribution est donne ici. Enfin, en troisieme et dernier lieu, on retrouve une analyse exhaustive du probleme du crossover dans le modele de percolation avec une resistance non-nulle pour les liens normalement isolants. A l'aide du groupe de renormalisation de Migdal-Kadanoff, on montre qu'il existe un seul exposant de crossover et une seule longueur de coherence. D'autres longueurs de correlation peuvent etre definies, mais elles demeurent dans un rapport fixe le long des axes propres du groupe de renormalisation. La multifractalite est donc, pour ce modele et ceux qui peuvent etre formules de facon analogue, compatible avec l'existence d'une seule longueur de coherence. Ces resultats sont d'application directe pour les proprietes electriques des milieux desordonnes.

  7. Occurrence of anti-Neospora caninum and anti-Toxoplasma gondii IgG antibodies in goats and sheep in western Maranhão, Brazil Ocorrência de anticorpos IgG anti-Neospora caninum e anti-Toxoplasma gondii em caprinos e ovinos do oeste do Maranhão, Brasil

    Directory of Open Access Journals (Sweden)

    Larissa Martins de Brito Moraes

    2011-12-01

    Full Text Available Neosporosis and toxoplasmosis are parasitic diseases which can cause reproductive problems in goats and sheep. The current study aimed to determine the occurrence of anti-Neospora caninum and anti-Toxoplasma gondii IgG antibodies in goats and sheep from the districts of Amarante do Maranhão and Buritirana, Imperatriz microregion, western area of Maranhão State, northeastern Brazil, and to assess factors associated to infection by these etiologic agents. Blood samples from 110 animals (46 goats and 64 sheep from five herds were collected, and indirect immunofluorescence assay was used for serological testing. Of 46 goat samples, 17.39% (n = 8 showed anti-N. caninum antibodies and 4.35% (n = 2 anti-T. gondii, while of 64 sheep samples 4.69% (n = 3 and 18.75% (n = 12 showed anti-N. caninum and anti-T. gondii antibodies, respectively. No significant difference regarding the presence of domestic cats and/or dogs on the property and veterinary care was seen for both etiologic agents studied. However, food supplementation and animal reproductive failure were significantly (p A neosporose e a toxoplasmose são doenças parasitárias que podem causar problemas reprodutivos em caprinos e ovinos. O objetivo deste estudo foi determinar a ocorrência de anticorpos IgG anti-Neospora caninum e anti-Toxoplasma gondii em caprinos e ovinos dos municípios de Amarante do Maranhão e Buritirana, microrregião de Imperatriz, Oeste maranhense, Nordeste do Brasil, bem como avaliar fatores associados à infecção por esses agentes etiológicos. Amostras de sangue de 110 animais (46 caprinos e 64 ovinos, provenientes de cinco propriedades, foram coletadas, e a reação de imunofluorescência indireta utilizada para o diagnóstico sorológico. Das 46 amostras de caprinos, 17,39% (n = 8 apresentaram anticorpos anti-N. caninum e 4,35% (n = 2 anti-T. gondii, enquanto das 64 amostras de ovinos, 4,69% (n = 3 e 18,75% (n = 12 apresentaram anticorpos anti-N. caninum e anti

  8. Triagem sorológica de familiares de pacientes com doença celíaca: anticorpos anti-endomísio, antitransglutaminase ou ambos? Serological screening of relatives of celiac disease patients: antiendomysium antibodies, anti-tissue transglutaminase or both?

    Directory of Open Access Journals (Sweden)

    Shirley Ramos da Rosa Utiyama

    2007-06-01

    -negativas. O impacto desse fato implica que tais familiares deixarão de ser submetidos a biopsia intestinal para confirmação do diagnóstico da doença, e conseqüentemente, ao tratamento adequado e precoce.BACKGROUND: Celiac disease is the most common intestinal disorder of caucasian populations and presents a prevalence of 8% to 18% between the relatives of patients. The anti-endomysial (IgA-EmA and anti-tissue transglutaminase antibodies (IgA-tTG have represented an important non invasive and sensitivity method of screening and diagnosis of celiac disease in risk groups and populations. AIM: To investigate the prevalence of IgA-EmA and IgA-tTG antibodies in relatives of celiac patients and verify the degree of concordance between them. METHODS: One hundred and seventy seven relatives of celiac patients (76(feminino; 101(masculino; 2-79 years and 93 healthy individuals were evaluated (34(feminino; 59(masculino; 2-71 years. IgA-EmA were detected by indirect immunofluorescence, with human umbilical cord as substrate, while anti-IgA-tTG titers were measured by enzyme-linked immunosorbent assay (ELISA, using commercial kit. RESULTS: Total positivity to antibodies in relatives of celiac patients was of 21% (37/177, and showed significant difference compared to control group (0%; 0/93. Twelve percent (21/177 of celiac disease relatives were positive to IgA-EmA, 13.56% (24/177 to IgA-tTG, and 4.52% (8/177 to both assays simultaneously. The concordance between both methods was 83.6% (148/177 and the discordance was 16.4% (29/177, with a positive and significant correlation (r = 0.435. Among the concordant results, 79.1% (140/177 were negative and 4.52% (8/177 were positive to both antibodies. Among the discordant results, 7.34% (13/177 were positive to IgA-EmA and negative to IgA-tTG, while 9.04% (16/177 were negative to IgA- EmA and positive to IgA-tTG. CONCLUSION: Although the high positivity to IgA-EmA and IgA-tTG emphasizes the importance of the serological screening in

  9. Vasculitis asociadas a anticuerpos anti-citoplasma de neutrófilos: Clínica y tratamiento

    Directory of Open Access Journals (Sweden)

    María Virginia Paolini

    2013-04-01

    Full Text Available Las vasculitis asociadas a anticuerpos anti-citoplasma de neutrófilos (ANCA comprenden a un grupo de enfermedades caracterizadas por la inflamación de la pared de pequeños vasos. Analizamos las características epidemiológicas y clínicas en una serie de 47 pacientes: 23 (49% granulomatosis de Wegener (GW, 15 (32% poliangeítis microscópica (PAM y nueve (19% vasculitis limitada al riñón (VLR. La edad media al inicio de los síntomas fue de 50.7 ± 14.9 años. La manifestación clínica más frecuente fue el compromiso renal en 41 (87% pacientes, seguido por el pulmonar en 26 (55% y el otorrinolaringológico en 17 (36%. En 26 (55% se asoció compromiso renal y pulmonar. La forma clínica más frecuente fue la generalizada en 23 (49%, seguida por la grave en 18 (38%. El 89% presentaron determinaciones de ANCA positivas. Cuatro (8% no recibieron tratamiento inmunosupresor de inicio. De los 43 que recibieron tratamiento de inicio, 29 (67% tuvieron remisión completa, con un tiempo de remisión promedio de 35.3 meses. Once (26% presentaron recaídas, diez (91% recaídas mayores y uno (9% menor. Doce (28% fallecieron, siete en forma temprana y cinco durante la evolución de la enfermedad. Quince (31% evolucionaron a insuficiencia renal crónica. Los 26 pacientes en seguimiento tuvieron respuesta al tratamiento y 20 (77% de ellos estaban en remisión al finalizar el estudio. Las vasculitis asociadas a ANCA continúan siendo enfermedades de alta morbilidad y mortalidad, a pesar de las mejorías logradas con los tratamientos inmunosupresores.

  10. Clinical outcomes after hepatitis C infection from contaminated anti-D immune globulin. Irish Hepatology Research Group.

    LENUS (Irish Health Repository)

    Kenny-Walsh, E

    2012-02-03

    BACKGROUND AND METHODS: In February 1994, batches of anti-D immune globulin used in Ireland during 1977 and 1978 to prevent Rh isoimmunization were found to be contaminated with hepatitis C virus (HCV) from a single infected donor. In March 1994, a national screening program was initiated for all women who had received anti-D immune globulin between 1970 and 1994. Of the 62,667 women who had been screened when this study began, 704 (1.1 percent) had evidence of past or current HCV infection, and 390 of those 704 (55 percent) had positive tests for serum HCV RNA on reverse-transcription-polymerase-chain-reaction analysis. All 390 were offered a referral for clinical assessment and therapy. We evaluated 376 of these 390 women (96 percent); the other 14 were not seen at one of the designated treatment centers. RESULTS: The mean (+\\/-SD) age of the 376 women was 45+\\/-6 years at the time of screening. They had been infected with hepatitis C for about 17 years. A total of 304 women (81 percent) reported symptoms, most commonly fatigue (248 [66 percent]). Serum alanine aminotransferase concentrations were slightly elevated (40 to 99 U per liter) in 176 of 371 women (47 percent), and the concentrations were 100 U per liter or higher in 31 (8 percent). Liver biopsies showed inflammation in 356 of 363 women (98 percent); in most cases the inflammation was slight (41 percent) or moderate (52 percent). Although the biopsy samples from 186 of the 363 women (51 percent) showed evidence of fibrosis, only 7 women (2 percent) had probable or definite cirrhosis. Two of the seven reported excessive alcohol consumption. CONCLUSIONS: Most of the women with HCV infection 17 years after receiving HCV-contaminated anti-D immune globulin had evidence of slight or moderate hepatic inflammation on liver biopsy, about half had fibrosis, and 2 percent had probable or definite cirrhosis.

  11. ¿Eugenesia liberal? Aproximaciones a partir de la propuesta anti-historicista de Michel Foucault

    Directory of Open Access Journals (Sweden)

    Gabriel Dalmau, Iván

    2014-12-01

    Full Text Available In this paper we try to contribute in the current philosophical and political debate concerning certain medical practices and their relationship with a “new liberal eugenics”. Hence, we focus on the triad constituted by the imbrications between human sciences, biopolitical techniques and government technologies of population under the construction of the “human capital” as a problem, in order to genealogically account for the question that triggers this work.En el presente trabajo buscaremos intervenir en el debate filosófico – político actual respecto de si ciertas prácticas biomédicas pueden ser consideradas como una “nueva eugenesia liberal”. Nos centraremos, entonces, en la tríada constituida por la imbricación entre ciencias humanas, técnicas biopolíticas y tecnologías de gobierno de la población en el marco de la construcción del “capital humano” como problema, para dar cuenta genealógicamente del interrogante que opera como disparador del presente trabajo.

  12. Low-dimensional gravities as gauge theories with non-compact groups

    International Nuclear Information System (INIS)

    Cangeni, D.

    1993-01-01

    In another note presented in these Proceedings it is shown that the two main lineal gravities can be given a gauge formulation. If it is already known that one of them the Sitter model - is a dimensional reduction of a Chern-Simons model in (2+1) dimensions, it was not clear whether the other one - the extended Poincare model follows from a similar reduction. The purpose of this note is to show that this is indeed the case provide we start in 2+1 dimensions with an extension ISO(2,1) of the Poincare groups as gauge group of a Chern-Simons model. We first show that this model gives a new proposal for gravity in 2*1 dimensions, since we get classically the Einstein's equations. Performing then a dimensional reduction, we recover not only the extended Poincare model but also the de Sitter one; hence, both lineal gravities get unified in the reduced model. (Author) 6 refs

  13. ¿Es necesario investigar anticuerpos IgM contra el virus de la hepatitis A cuando el enzimograma hepático es normal? Is it necessary to investigate anti-hepatitis A virus (HAV IgM antibodies when the hepatic enzymogram is normal?

    Directory of Open Access Journals (Sweden)

    C. Coitinho

    2007-09-01

    Full Text Available La hepatitis por virus A (VHA es la más frecuente de las hepatitis virales en el mundo, especialmente en los países subdesarrollados. Donde esta enfermedad es endémica, se suelen realizar un gran número de estudios de laboratorio para confirmarla. El objetivo del presente trabajo fue evaluar la utilidad de investigar anticuerpos IgM anti hepatitis A (IgM anti-VHA para el diagnóstico de la VHA en pacientes con niveles séricos normales de aspartato y alanina aminotransferasas (AST/ALT. Todos los pacientes que concurrieron al laboratorio con solicitud de enzimograma hepático y anticuerpos IgM anti-VHA durante el período octubre 2005-marzo 2006 fueron evaluados en este estudio. Los datos clínicos más frecuentes fueron presunción de hepatitis e ictericia (27,5 y 12,7%. La determinación de IgM anti-VHA se realizó por ensayo inmunoenzimático de micropartículas (MEIA; la de enzimas hepáticas en un multianalizador. De los 158 pacientes estudiados, 84 tenían valores elevados de AST/ALT; dentro de este grupo, el 82% fue reactivo para IgM anti-VHA. Los 74 pacientes restantes mostraron niveles normales de AST/ALT y solo 7 de ellos, bajo control de evolución por VHA ya confirmada, fueron reactivos para IgM anti-VHA. El 49% de los pacientes IgM anti-VHA reactivos correspondió a menores de 10 años. De acuerdo con estas observaciones, sugerimos que los estudios de laboratorio para confirmar infección aguda por VHA deberían realizarse en forma secuencial, ya que es innecesaria la determinación de anticuerpos IgM anti-VHA cuando las aminotransferasas séricas son normales.Type A viral Hepatitis (HAV is the most frequent viral hepatitis around the world, especially in low income countries. In order to confirm this disease, a lot of laboratory tests are annually carried out where HAV is endemic. Our objective was to establish the utility of investigating anti-hepatitis A virus (HAV IgM antibodies for HAV diagnosis in patients with normal

  14. USO DE ANTI-HELMÍNTICOS E BIOESTIMULANTES NO DESEMPENHO DE BOVINOS DE CORTE SUPLEMENTADOS A PASTO NO ESTADO DO PARÁ EFFECTS OF VERMIFUGES AND BIOSTIMULANTS ON BEEF CATTLE PERFORMANCE UNDER PASTURE SUPPLEMENTATION IN PARÁ STATE

    Directory of Open Access Journals (Sweden)

    Sâmia Rubielle Silva de Castro

    2009-07-01

    Full Text Available O experimento avaliou o efeito da vermifugação e da utilização de bioestimulantes no ganho de peso e no escore de condição corporal (ECC de bovinos de corte, criados em sistema de pastejo rotacionado com suplementação a pasto, no Estado do Pará, durante 160 dias. Foram utilizados 132 bovinos machos não castrados, com idade média de 24 meses, da raça Nelore (Bos taurus indicus. Os grupos experimentais compreenderam o grupo G1 (controle; n=33, G2 (moxidectina 1%; n=33, G3 (moxidectina 10%; n=33 e G4 (ivermectina 3,15%; n=33. Em todos os grupos foram estabelecidas três subparcelas, a fim de serem testados dois bioestimulantes de crescimento animal (bioestimulante 1 e bioestimulante 2. Não houve diferença estatística significativa no ganho de peso médio, no ECC e nas contagens de OPG entre animais do G1, G2, G3 e G4, independentemente dos anti-helmínticos e/ou bioestimulantes usados. Contudo, o tratamento baseado na associação de moxidectina 1% e o bioestimulante 2 apresentou maior receita líquida e incrementou a lucratividade da terminação em 1,24%. Os resultados sugerem que não há necessidade de um controle contra nematódeos durante a terminação, desde que os animais apresentem uma baixa carga parasitária, porém o uso de fármacos pode, sob certas condições, apresentar resultado econômico favorável.

    PALAVRAS-CHAVES: Anti-helmíntico, bovinocultura, crescimento, rentabilidade, sistema de produção.
    The experiment evaluated the effect of vermifuges and biostimulants on weight gain and body condition score (BCS of beef cattle, created in pasture supplementation system, in the State of Pará, during 160 days. Experimental animal were 132 Nelore (Bos taurus indicus, non-castrated male, with average age of 24 months. Experimental groups were: G1 group (control; n=33, G2 (1% moxidectin; n=33, G3 (10% moxidectin; n=33 and G4 (3.15% ivermectin; n=33. Each group was divided in three plots, in order to test

  15. Pesquisa de anticorpos anti-Neospora caninum em bovinos leiteiros, cães e trabalhadores rurais da região Sudoeste do Estado de Mato Grosso Inquiry of antibodies anti-Neospora caninum in dairy cattle, dogs and rural workers of the south-west region of Mato Grosso State

    Directory of Open Access Journals (Sweden)

    Ana Helena Benetti

    2009-12-01

    Full Text Available Considerando a importância da neosporose interferindo na produtividade animal, avaliou-se a frequência de anticorpos anti-Neospora caninum em amostras de soros de bovinos leiteiros da Região Sudoeste do Estado de Mato Grosso, Brasil, complementando-se com amostras sorológicas colhidas de cães e de humanos que conviviam nas mesmas propriedades rurais amostradas. Um total de 1.036 amostras de soros foram analisadas, sendo 932 de fêmeas bovinas leiteiras, 37 de cães e 67 de humanos, provenientes de 24 propriedades e examinados por meio da reação de imunofluorescência indireta (RIFI. As amostras de soros humanos reagentes foram testadas novamente por Western-blotting para confirmação dos resultados. Anticorpos anti-N. caninum foram encontrados em 499 bovinos (53,5%, em pelo menos um animal positivo por propriedade, em 25 caninos (67,6% e em sete humanos (10,5%. Não houve diferença significativa no número de bovinos positivos por faixa etária. Os resultados obtidos indicam uma ampla disseminação de N. caninum na região estudada.Considering the importance of neosporosis in the animal health and production, the frequency of antibodies to Neospora caninum was evaluated in dairy cattle of the Southwestern region of Mato Grosso State, Brazil, in addition to serum samples obtained from dogs and humans living in the farms. A total of 1036 serum samples were analyzed, from which 932 were from dairy bovine females, 37 from dogs and 67 from humans, from 24 farms and examined by the indirect fluorescent antibody test (IFAT. Reactive human serum samples were retested by Western-blotting to confirm the results. Antibodies to N. caninum were found in 499 cattle sera (53.5 %, with at least one positive in each farm, 25 dog sera (67.6 % and seven human sera (10.5 %. There was no significant difference in the number of positive cattle sera according to age group. The results indicate a wide dissemination of N. caninum in the studied region.

  16. L'accompagnement de la construction de la chaîne associative groupale dans un groupe de patients schizophrènes

    OpenAIRE

    Gimenez, Guy; Pinel, Jean-Pierre; Vacheret, Claudine

    2013-01-01

    International audience; Le travail a pour but d’étudier, à partir de séquences cliniques d’un groupe de paroles, constitué de patients schizophrènes en institution spécialisée, le processus de construction d’une chaîne associative groupale. Les auteurs décrivent comment les productions morcelées et dissociées de patients schizophrènes, délirants et hallucinés, en situation de groupe, peuvent, dans certaines conditions, devenir progressivement une chaîne associative de groupe, prenant en compt...

  17. [Group psychotherapy. Operative groups at the Instituto del servico de seguridad Social de los Trabajadores del Estado (ISSSTE)].

    Science.gov (United States)

    Margolis, J

    1977-01-01

    An operational group is defined; how operational groups theory was applied at an ISSSTE clinic is described. It is underlined how operational groups promote change around the corerstone of a "task". The vicissitudes of an operational group with four psychiatrists who worked in community psychiatry at the ISSSTE, are described.

  18. Análisis de Factores que Influyen en el Desarrollo de Normas Ambientales y en la Conducta Anti-Ecológica

    Directory of Open Access Journals (Sweden)

    Martha Frías Armenta

    2009-01-01

    Full Text Available El propósito del presente estudio fue evaluar el impacto de variables presumiblemente relacionadas con el desarrollo de normas ambientales, dado que las transgresiones ambientales son una forma particular de conducta antisocial. 186 estudiantes de licenciatura en una universidad mexicana contestaron un cuestionario que midió su auto-reporte de comportamiento anti-ecológico (considerado como variable dependiente, VD, sus normas personales, sus normas sociales, su identidad social, su percepción de legitimidad en las autoridades y en los procesos jurídicos, y la disuasión que detectaban en los marcos legales. Los datos fueron analizados a través de un modelo de ecuaciones estructurales. Los resultados del mismo mostraron que las normas personales y sociales tuvieron un efecto directo en la conducta antiecológica, siendo negativo el de las primeras y positivo el de las segundas, mientras que la disuasión influyó negativa e indirectamente en la VD, a través de las normas sociales. La legitimidad percibida tuvo un efecto indirecto y negativo en la conducta anti-ecológica, a través de la disuasión y de las normas sociales y personales. Los resultados son coherentes con estudios previos acerca del seguimiento de normas ordinarias, en donde las normas sociales y la disuasión ejercen sus efectos a través de la internalización de las primeras, manifestándose como normas morales personales.

  19. Suivi ecologique du groupe de gorille ''Buka'' en cours d'habituation ...

    African Journals Online (AJOL)

    à la difficile conciliation des enjeux de la conservation, d'une part et du développement, d'autre part, surtout autour des grands singes, notamment les Gorilles qui constituent un groupe zoologique d'un grand attrait touristique. Conscient de cet enjeu, nous avons mené au Centre de Recherche Mondika, pendant neuf mois, ...

  20. Chemoradiotherapy of esophagus cancers: prognostic value of anti-P53 and anti-ras circulating antibodies; Chimioradiotherapie des cancers de l'oesophage: valeur pronostique des anticorps circulants anti-P53 et anti-ras

    Energy Technology Data Exchange (ETDEWEB)

    Blanchard, P.; Quero, L.; Pacaud, V.; Baruch-Hennequin, V.; Maylin, C.; Hennequin, C. [Hopital Saint-Louis, Service d' Oncologie-radiotherapie, 75 - Paris (France); Schlageter, M.H. [Hopital Saint-Louis, Service de Medecine Nucleaire, 75 - Paris (France)

    2007-11-15

    The presence of anti-p53 antibodies makes suspect a resistance to the chemoradiotherapy and has to make envisage other approaches that the chemo - radiotherapy by 5-fluoro-uracil-cisplatin (surgery, intensification, targeted therapeutic). (N.C.)

  1. Serodiagnóstico de giardiosis: identificación de inmunoglobulina G anti-Giardia duodenalis en suero mediante ELISA

    Directory of Open Access Journals (Sweden)

    Sofía Duque

    2001-09-01

    Full Text Available El diagnóstico de la infección por Giardia duodenalis se basa en la identificación de quistes o trofozoítos en materia fecal, alcanzando una sensibilidad máxima de 85% en muestras seriadas, debido a la excreción intermitente de quistes. Aunque la determinación de anticuerpos no permite diferenciar entre una infección pasada y una reciente, si podría ayudar en el diagnóstico diferencial. El presente estudio tuvo como objetivos estandarizar y evaluar una prueba inmunoenzimática (ELISA para la detección de anticuerpos tipo IgG anti-Giardia duodenalis en sueros de pacientes con la infección. La preparación del antigeno se hizo a partir de trofozoitos cultivados que, inicialmente, fueron obtenidos del intestino de gerbils (Meriones unguiculatus infectados experimentalmente con quistes purificados a partir de muestras positivas de materia fecal humana. Para la estandarización y evaluación de la prueba, se emplearon 60 sueros de pacientes con giardiosis comprobada parasitológicamente (muestras positivas y 47 sueros de cordón umbilical recién cortado (muestras negativas. Como conjugado, se utilizó anti-lgG humana ligada a fosfatasa alcalina. La concentración óptima de antígeno de trofozoíto de G. duodenalis fue de 15 ug/ml y las diluciones óptimas de suero y conjugado fueron 1:25 y 1:400, respectivamente. El valor del punto de corte (absorbancia fue 0,300. Los parámetros de la prueba fueron: sensibilidad, 98,3% (intervalo de confianza de 95% (lC 95%: 89,9%-99,974; especificidad, 957% (IC 95%:84,3%-99,3%; valor predictivo positivo, 96,7% (IC 95%: 87,6%-99,4%, y valor predictivo negativo, 97,8% (IC 95%: 87,0%-99,9%. La prueba ELlSA descrita contribuirá a mejorar el diagnóstico de giardiosis y podrá ser empleada para estudios epidemiológicos de seroprevalencia.

  2. Extremal limits of the C metric: Nariai, Bertotti-Robinson, and anti-Nariai C metrics

    Science.gov (United States)

    Dias, Óscar J.; Lemos, José P.

    2003-11-01

    In two previous papers we have analyzed the C metric in a background with a cosmological constant Λ, namely, the de Sitter (dS) C metric (Λ>0), and the anti de Sitter (AdS) C metric (Λmetric in flat spacetime (Λ=0). These exact solutions describe a pair of accelerated black holes in the flat or cosmological constant background, with the acceleration A being provided by a strut in between that pushes away the two black holes or, alternatively, by strings hanging from infinity that pull them in. In this paper we analyze the extremal limits of the C metric in a background with a generic cosmological constant Λ>0, Λ=0, and ΛSchwarzschild solution by taking an appropriate limit, where the black hole event horizon approaches the cosmological horizon. Similarly, one can generate the Bertotti-Robinson metric from the Reissner-Nordström metric by taking the limit of the Cauchy horizon going into the event horizon of the black hole, as well as the anti-Nariai metric by taking an appropriate solution and limit. Using these methods we generate the C-metric counterparts of the Nariai, Bertotti-Robinson, and anti-Nariai solutions, among others. These C-metric counterparts are conformal to the product of two two-dimensional manifolds of constant curvature, the conformal factor depending on the angular coordinate. In addition, the C-metric extremal solutions have a conical singularity at least at one of the poles of their angular surfaces. We give a physical interpretation to these solutions, e.g., in the Nariai C metric (with topology dS2×S˜2) to each point in the deformed two-sphere S˜˜2 corresponds a dS2 spacetime, except for one point which corresponds to a dS2 spacetime with an infinite straight strut or string. There are other important new features that appear. One expects that the solutions found in this paper are unstable and decay into a slightly nonextreme black hole pair accelerated by a strut or by strings. Moreover, the Euclidean version of these

  3. Uso de drogas antiobesidade entre estudantes universitários Use of anti-obesity drugs among college students

    Directory of Open Access Journals (Sweden)

    Maria do Carmo de Carvalho e Martins

    2011-10-01

    Full Text Available OBJETIVO: Avaliar o uso de drogas antiobesidade entre estudantes de uma universidade pública. MÉTODOS: Estudo transversal com amostra probabilística constituída por 664 universitários. Foram observadas variáveis socioeconômicas, antropométricas e uso das drogas. O índice de massa corpórea (IMC e circunferência da cintura (CC foram classificados segundo critérios da Organização Mundial de Saúde. RESULTADOS: Uso atual ou anterior de agentes antiobesidade foi referido por 6,8% dos estudantes. As anfetaminas e as aminas simpaticomiméticas (40,5% foram as drogas mais usadas. Entre aqueles que referiram uso de agentes antiobesidade, 62,2% eram do sexo feminino. Apenas 31,1% das prescrições foram indicadas por médicos. As médias de IMC e CC foram maiores entre estudantes que referiram uso de tais drogas, mas 47% deles foram classificados como eutróficos pelo IMC, e 76,5% apresentavam medida de CC normal. CONCLUSÃO: O uso de drogas antiobesidade se mostrou preocupante, principalmente pela elevada proporção de uso sem indicação ou prescrição médica.OBJECTIVE: To evaluate the use of anti-obesity drugs among students attending a public university. METHODS: This was a cross sectional random study of 664 college students. Drug use, socioeconomic, and anthropometric variables were observed. Body mass index (BMI and waist circumference (WC were classified according to World Health Organization criteria. RESULTS: Current or previous use of anti-obesity drugs was reported by 6.8% of students. Amphetamine and sympathomimetic amines (40.5% were the most commonly used drugs. Among those who reported use of anti-obesity agents, 62.2% were female. Only 31.1% of medications were prescribed by doctors. Mean BMI and WC were higher among students reporting the use of such drugs, but 47% of them were classified as eutrophic by BMI, and 76.5% had normal WC measure. CONCLUSION: The use of anti-obesity drugs among college students is of concern

  4. Utilização, em politransfundidos, da pesquisa de anticorpos igm anti-trypanosoma cruzi e anti-toxoplasma gondii para detectar infecções pós-transfusionais recentes

    Directory of Open Access Journals (Sweden)

    Vicente Amato Neto

    1984-04-01

    Full Text Available Consideram os Autores que a pesquisa de anticorpos IgM no soro é tática capaz de revelar recentes infecções pós-transfusionais. Por isso, decidiram usar esse tipo de mensuração relativamente a grupo constituído por 101 politrans-fundidos, tendo abordado especificamente as aquisições de doença de Chagas e toxoplasmose. Através da investigação que realizaram, só em duas oportunidades encontraram anticorpos IgM anti-Trypanosoma cruzi ou anti-Toxoplasma gondii e, portanto, não evidenciaram expressivo panorama tradutor de processos há pouco tempo contraídos, como ainda, por meio de anticorpos IgG não identificaram números expressivos de pessoas com essas protozooses. No entanto, detectaram a expressiva taxa de 4,9% de casos de doença de Chagas muito provavelmente decorrentes da hemoterapia. A despeito da relevância não acentuada dos resultados que obtiveram, julgaram os Autores ser válido estimular a efetivação de outros estudos congêneres e correlatos, aptos a contribuir para aqui-latamento de riscos pertinentes à prática hemoterápica.

  5. Ausência de anticorpos antilipoproteína lipase na doença de Behçet Lack of anti-lipoprotein lipase in Behçet's disease

    Directory of Open Access Journals (Sweden)

    Jozélio Freire de Carvalho

    2009-12-01

    Full Text Available OBJETIVO: A recente descrição de anticorpos antilipoproteína lipase (anti-LPL associados à dislipoproteinemia levounos a analisar sua presença e possível associação com achados clínicos e laboratoriais em pacientes com doença de Behçet. PACIENTES E MÉTODOS: Trinta e oito pacientes consecutivos com doença de Behçet [critérios do Grupo de Estudos Internacional em Doença de Behçet (International Study Group on Behçet's Disease - ISGBD] foram testados para a presença de anticorpos anti-LPL através da técnica de ELISA. Foi realizada avaliação clínica e laboratorial, incluindo perfil lipídico de jejum, pesquisa de autoanticorpos e marcadores inflamatórios (PCR, VHS na inclusão dos pacientes. Os critérios de exclusão foram quaisquer condição que afetassem o perfil lipídico. RESULTADOS: A média de idade foi de 42 ± 9 anos, sendo 68% do sexo feminino e 68% da cor branca. O tempo médio de duração da doença foi de 9,8 ± 7,5 anos. Vinte e nove por cento dos pacientes apresentaram história de trombose. Os níveis de PCR estavam elevados em 31% dos pacientes e VHS aumentada foi detectada em 31%, com níveis médios de 5,95 ± 10,3 mcg/mL e 14,5 ± 13,2 mm/1ªhora, respectivamente. Cerca de 47% dos pacientes estavam tomando prednisona, com dose média de 7,6 ± 10,8 mg/dia. Quanto aos níveis de risco cardiovascular da NCEP/ATPIII, colesterol elevado foi verificado em 26%, triglicerídeos em 18%, HDL baixo em 15% e elevado LDL em 25% dos pacientes com Behçet. Os níveis médios de CT foram 198 ± 48 mg/dL, de triglicerídeos 121 ± 61 mg/dL, HDL 52.4 ± 14.7 mg/dL e LDL 119 ± 35 mg/dL. Anticorpos anti-LPL to subtipo IgG foram detectados em 0/30 pacientes com Behçet. CONCLUSÃO: Esses dados aqui apresentados corroboram uma ausência de ligação entre inflamação, resposta imunológica e dislipoproteinemia nos pacientes com doença de Behçet e sugerem que outros mecanismos estão associados à dislipidemia vista

  6. Anti-Taenia solium metacestodes antibodies in serum from blood donors from four cities of Triângulo Mineiro area, Minas Gerais, Brazil, 1995 Anticorpos anti-formas metacestódeas de Taenia solium em amostras de soros de doadores de sangue de quatro cidades da região do Triângulo Mineiro, Minas Gerais, Brasil, 1995

    Directory of Open Access Journals (Sweden)

    Elisângela de Paula SILVEIRA-LACERDA

    2002-07-01

    Full Text Available Serological survey was performed to detect IgG antibodies anti-Taenia solium metacestodes in blood donors of Hemocentro Regional de Uberlândia, Minas Gerais, Brazil. A total of 1133 sera from blood donors coming from four cities of Triângulo Mineiro area were analyzed by the indirect fluorescence antibody test (IFAT and the enzyme linked immunosorbent assay (ELISA. Specific IgG antibodies were found in 5.6% of the studied population, showing differences in the positive rates according to their origin: Araguari (13.5%, Tupaciguara (5.0%, Monte Alegre de Minas (4.8% and Uberlândia (4.7%. The results indicate the probable endemicity of cysticercosis in this population.Realizou-se pesquisa sorológica para detectar anticorpos IgG anti-formas metacestódeas de Taenia solium em doadores de sangue do Hemocentro Regional de Uberlândia, Minas Gerais, Brasil. O total de 1133 amostras de soros de doadores de sangue de quatro cidades do Triângulo Mineiro foi analisado pelo teste de imunofluorescência indireta (IFI e o teste imunoenzimático (ELISA. Anticorpos IgG específicos foram detectados em 5,6% da população estudada, mostrando diferenças nas taxas de positividade de acordo com suas cidades de origens: Araguari (13,5%, Tupaciguara (5,0%, Monte Alegre de Minas (4,8% e Uberlândia (4,7%. Os resultados indicam a provável endemicidade de cisticercose nesta população.

  7. Soroprevalência de anticorpos anti-Ehrlichia canis em cães de Cuiabá, Mato Grosso Seroprevalence anti-Ehrlichia canis antibodies in dogs of Cuiabá, Mato Grosso

    Directory of Open Access Journals (Sweden)

    José Nivaldo da Silva

    2010-06-01

    Full Text Available A erliquiose canina é uma doença transmitida por carrapatos Rhipicephalus sanguineus e ocasionada pela Ehrlichia canis, bactéria intracelular obrigatória. O presente estudo verificou a prevalência de anticorpos anti-E. canis em 254 cães de quatro regiões administrativas de Cuiabá, Estado de Mato Grosso, por imunofluorescência indireta, observando-se uma prevalência de 42,5% (108/254 sem diferença significativa entre as regiões. As variáveis idade, raça, sexo, hábitat, acesso à zona rural e presença de carrapatos foram analisadas. Os títulos de anticorpos variaram entre 1:40 a 1:2.560. Somente 32 (29,63% cães soropositivos estavam infestados por carrapatos, todos R. sanguineus. O resultado encontrado confirma que não há predisposição racial, sexual ou etária, enquanto a menor ocorrência de cães reagentes no intradomicílio provavelmente está relacionada à baixa infestação por carrapato, apesar de não ter sido observada diferença significativa entre os cães com ou sem a infestação com o carrapato vetor.Canine ehrlichiosis is a disease transmitted by ticks Rhipicephalus sanguineus and caused by Ehrlichia canis, obligatory intracellular bacteria. The present study examined the prevalence of anti-E. canis in 254 dogs from four administrative regions of Cuiabá, Mato Grosso, by indirect immunofluorescence assay. There was a prevalence of 42.5% (108/254 without significant difference between the studied regions. The variables age, breed, sex, habitat, access to rural and ticks were analyzed. The antibody titers ranged from 1:40 to 1:2,560. Only 32 (29.63% seropositive dogs were infested with ticks, all R. sanguineus. The results confirm that do not have breed, sex or age predisposition to ehrlichiosis due E. canis, while the lowest occurrence of reactive dogs indoors probably related to low tick infestation, although no significant difference between dogs with or without infestation with the tick vector.

  8. Resistência de estafilococos de origem canina, frente à drogas anti microbianas em Londrina, PR.

    Directory of Open Access Journals (Sweden)

    Amauri Alcindo Alfieri

    1985-11-01

    Full Text Available The sensitivity of 71 staphylococci (S. aureus and S. intermedius, isolated from dogs with signs of skin disease, to J1 chemotherapeutic agents was determined. Of the strains, 55(77,46% were resistant to amicacin, 29(40,84% to penicillin G, 26(36,61% to ampicillin, 24(33,80% to tetracycline, 15(21,13% to chloramphenicol, 12(16,90% to erytromycin, 11(15,49% to kanamycin, 8(11,27% to gentamycin, 5(7,04% to sulfazothrim, 2(2,82% to cefoxithin and 1(1,41% to oxacillin.Foram examinadas 71 cepas de estafilococos (S. aureus e S. intermedius isoladas a partir de cães com pioderma, frente a 11 substâncias antimicrobianas. Das cepas, 55(77,46% apresentaram resistência à amicacina, 29(40,84% à penicilina G, 26(36,61% à ampicilina, 24(33,80% à tetraciclina, 15(21,13% ao cloranfenicol, 12(16,90% à eritromicina, 11(15,49% à canamicina, 8(11,27% à gentamicina, 5(7,04% ao sulfazotrim, 2(2,82% à cefoxitina e 1(1,41% a oxacilina.

  9. The anti-inflammatory activity of standard aqueous stem bark extract of Mangifera indica L. as evident in inhibition of Group IA sPLA2.

    Science.gov (United States)

    Dhananjaya, Bhadrapura Lakkappa; Shivalingaiah, Sudharshan

    2016-03-01

    The standard aqueous stem bark extract is consumed as herbal drink and used in the pharmaceutical formulations to treat patients suffering from various disease conditions in Cuba. This study was carried out to evaluate the modulatory effect of standard aqueous bark extract of M. indica on Group IA sPLA2. M. indica extract, dose dependently inhibited the GIA sPLA2 (NN-XIa-PLA2) activity with an IC50 value 8.1 µg/ml. M. indica extract effectively inhibited the indirect hemolytic activity up to 98% at ~40 µg/ml concentration and at various concentrations (0-50 µg/ml), it dose dependently inhibited the edema formation. When examined as a function of increased substrate and calcium concentration, there was no relieve of inhibitory effect on the GIA sPLA2. Furthermore, the inhibition was irreversible as evidenced from binding studies. It is observed that the aqueous extract ofM. indica effectively inhibits sPLA2 and it is associated inflammatory activities, which substantiate their anti-inflammatory properties. The mode of inhibition could be due to direct interaction of components present in the extract, with sPLA2 enzyme. Further studies on understanding the principal constituents, responsible for the anti-inflammatory activity would be interesting to develop this into potent anti-inflammatory agent.

  10. Evaluation of anti-Schistosoma mansoni igG antibodies in patients with chronic schistosomiasis mansoni before and after specific treatment Avaliação da presença de anticorpos IgG anti-Schistosoma mansoni no soro de pacientes com esquistossomose mansônica crônica, antes e após tratamento específico

    Directory of Open Access Journals (Sweden)

    Célia Maria V. VENDRAME

    2001-06-01

    Full Text Available The circumoval precipitin test (COPT, enzyme-linked immunosorbent assay (ELISA and the immunoblotting anti-adult worm antigen (AWA and soluble egg antigen (SEA tests were applied to 17 chronically schistosome-infected patients for the detection of anti-Schistosoma mansoni antibodies before and on four occasions after oxamniquine administration over a period of six months. Compared to a control group, schistosomiasis patients showed high levels of IgG antibodies in AWA and SEA-ELISA. A decrease in IgG levels was observed six months after treatment, although negative reactions were not obtained. Significant decreases in IgG1, IgG3 and, mainly, IgG4, but not anti-SEA IgG2 levels were observed six months after treatment, again without negativity. Analysis of anti-AWA IgG antibodies by immunoblotting before treatment showed a 31 kDa strand in 14 patients (82% which disappeared in three cases up to six months after treatment; furthermore, anti-SEA IgG antibodies showed the same band in nine patients (53% before treatment, which disappeared in only four cases up to six months after treatment.Em 17 pacientes com infecção crônica por Schistosoma mansoni utilizaram-se os testes de reação periovular, imunoenzimático (ELISA e imunoblotting, empregando-se antígenos obtidos a partir de vermes adultos (AWA ou de ovos de S. mansoni (SEA, para detecção de anticorpos anti-S. mansoni, antes e em quatro ocasiões após tratamento com oxamniquine. Quando cotejados a grupo controle os pacientes esquistossomóticos revelaram altos níveis séricos de anticorpos IgG nos testes ELISA (anti-AWA e anti-SEA, não se observando, porém, negativação até seis meses após tratamento específico. Encontrou-se, entretanto, decréscimo significativo, sem negativação, dos níveis de IgG1, IgG3 e, principalmente, IgG4, quando se utilizou antígeno solúvel obtido a partir de ovos de S. mansoni (SEA, seis meses após administração de oxamniquine. O mesmo não foi

  11. Redes transnacionales, antiperonismo y Guerra Fría: Los orígenes de la Asociación Argentina por la Libertad de la Cultura Transnational networks, anti-Peronism and Cold War: the origins of the Asociación Argentina por la Libertad de la Cultura

    Directory of Open Access Journals (Sweden)

    Jorge Nállim

    2012-06-01

    Full Text Available El artículo explora los procesos locales y transnacionales que llevaron a la creación de la Asociación Argentina por la Libertad de la Cultura en diciembre de 1955. La Asociación era la filial del Congreso por la Libertad de la Cultura, fundado en 1950 en Berlín como parte de la estrategia cultural estadounidense durante la Guerra Fría. Basado en el análisis de un amplio espectro de publicaciones e instituciones, el texto rastrea la densa red de relaciones personales, institucionales, ideológicas y políticas entre los intelectuales antiperonistas argentinos y entre ellos y sus colegas extranjeros que llevaron a la fundación de la Asociación. Estas relaciones, desarrolladas desde la década de 1930 y profundizadas por la experiencia peronista y la Guerra Fría, fueron facilitadas por trayectorias y temáticas comunes tales como la defensa de la libertad política y cultural y de la superioridad del mundo occidental, el antifascismo y el anticomunismo. El análisis, parte de un proyecto más amplio en curso, sienta las bases para el estudio futuro de la historia de la Asociación y de las redes intelectuales anticomunistas en América Latina durante la Guerra Fría.This article explores the local and transnational processes that resulted in the creation of the Asociación Argentina por la Libertad de la Cultura in December, 1955. The Asociación was a branch of the Congress for Cultural Freedom, which was created in Berlin in 1950 as part of the American cultural strategy during the Cold War. Based on the analysis of a broad group of publications and institutions, the text traces the dense network of personal, institutional, ideological and political relations among the anti-Peronist Argentine intellectuals and between them and their European colleagues that led to the creation of the Asociación. Those relations, developed since the 1930s and deepened by the Peronist experience and the Cold War, were facilitated by common trajectories

  12. Bacteriemia após exodontia unitária, empregando dois métodos de anti-sepsia intrabucal

    OpenAIRE

    ROCHA BARROS Valdemar Mallet da; ITO Izabel Yoko; AZEVEDO Rosa Vitória P.; MORELLO Danielle; ROSATELI Pedro Augusto; FILIPECKI Lara Cappato

    2000-01-01

    O objetivo do trabalho foi avaliar a freqüência de bacteriemias pós-exodontia utilizando dois métodos de anti-sepsia pré-operatória, identificando os microrganismos isolados de hemoculturas pós-extração e avaliando a sua suscetibilidade a antibióticos. Vinte e seis pacientes tiveram 33 dentes extraídos. Dezesseis casos foram submetidos a anti-sepsia com bochecho com 15 ml de gluconato de clorexidina a 0,12% por um minuto, seguido da fricção das faces dentais com cotonete embebido na mesma sol...

  13. Soutien institutionnel au Groupe de recherche en économie ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le nouveau site Web facilitera l'enregistrement des événements démographiques afin d'améliorer l'accès aux services pour tous. Le nouveau site Web et la nouvelle bibliothèque de ressources aideront à améliorer les systèmes d'information et d'enregistrement des faits d'état civil dans les pays en développement.

  14. Variáveis familiares preditoras do comportamento anti-social em adolescentes autores de atos infracionais

    Directory of Open Access Journals (Sweden)

    Janaína Thaís Barbosa Pacheco

    Full Text Available O objetivo deste estudo foi investigar variáveis individuais e familiares preditoras do comportamento anti-social. Os participantes foram 148 adolescentes, autores de atos infracionais, e 163 adolescentes não-infratores. Os adolescentes responderam individualmente a uma entrevista estruturada, que investigou estratégias educativas parentais, variáveis familiares e aspectos relacionados ao desenvolvimento do comportamento infrator. Uma análise de conteúdo das respostas permitiu a delimitação das principais práticas educativas relatadas pelos jovens. Uma análise de regressão indicou que o comportamento anti-social de familiares, o número de irmãos, o uso de drogas pelo adolescente, os conflitos na família e as práticas educativas parentais explicaram 53% da variância do comportamento infrator. Os resultados apontaram a importância da família no desenvolvimento da conduta infratora.

  15. Factors associated with adherence to antihypertensive treatment in a primary care unit Factores asociados con la adhesión al tratamiento antihipertensivo en unidad de salud Fatores associados à adesão ao tratamento anti-hipertensivo em unidade básica de saúde

    Directory of Open Access Journals (Sweden)

    Márcia Simonia Demoner

    2012-01-01

    Full Text Available OBJECTIVES: To analyze the adherence of patients to antihypertensive treatment conducted in a Primary Care Unit (PCU, as well as the related factors of low adherence to this therapy. METHODS: A quantitative, descriptive exploratory study of hypertensive patients interviewed in a PCU, using the Morisky-Green Test for assessing adherence or nonadherence with antihypertensive treatment. RESULTS: A prevalence of 64% of patients who were nonadherent to antihypertensive therapy was identified, and this was significantly related to the variables of: age, occupation, obesity, lack of other chronic disease, lack of employment, continuous use of prescription drugs, misunderstanding of the medical recommendations, and ignorance of the name of antihypertensive medication use. CONCLUSION: We found a high prevalence (64% of patients nonadherent to therapy, that was significantly associated with users who were: in the youngest age group, working, and presenting with overweight or obesity.OBJETIVOS: Analizar la adhesión de pacientes al tratamiento anti-hipertensivo realizado en una Unidad Básica de Salud (UBS, así como los factores relacionados a la baja adhesión a esa terapia. MÉTODOS: Estudio de naturaleza cuantitativa, exploratoria descritiva realizado con una muestra de 150 pacientes hipertensos entrevistados en una UBS, utilizándose el Test de Morisky-Green para la evaluación de la adhesión o no al tratamiento anti-hipertensivo. RESULTADOS: Fue identificada una prevalencia del 64% de pacientes no adherentes a la terapia anti-hipertensiva que estuvo significativamente asociada a las variables: grupo etáreo, ocupación, obesidad, ausencia de otra enfermedad crónica, falta de empleo de medicamentos de uso contínuo, incomprensión de las recomendaciones médicas y el desconocimiento del nombre del medicamento anti-hipertensivo utilizado. CONCLUSIÓN: Se constato una elevada prevalencia del 64% de pacientes no adherentes a la terapia que, fue

  16. Los [anti]silenos de Erasmo y el Lazarillo de Tormes

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    Marco Antonio Coronel Ramos

    2014-06-01

    This paper is a reading of El Lazarillo de Tormes from the perspective of the spiritual movements in Spain during the 16th century. From this perspective, the novel may be related to other works of reform of Christianity which arose within the Catholic Church. Thus the author of  El Lazarillo is related to those moralists who, in line with the Erasmianism, called for raising the moral level and training of the clergy. Taking into account these assumptions, El Lazarillo is studied as a narrative recreation of what Erasmus called antisileni. In this sense the novel reflects the importance which reverse values have acquired in the 16th century society, whereas in a deeper reading, it would be considered a knock on the conscience of the reader to persuade him to live with the true Christian virtues.

  17. Proposal of law relative to the creation of the Energie de France group; Proposition de loi relative a la creation du Groupe Energie de France

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-06-01

    This proposal of law concerns the fusion of the two French historical electric and gas utilities: Electricite de France (EdF) and Gaz de France (GdF). This proposition of fusion is motivated by the recent mutations of the gas and electric sectors: markets liberalization, separation between the energy production, transport, and commercialization activities, convergence and increasing integration of European markets, limitation of monopolies activity etc.. The solution proposed in this document is to create a group named 'Energie de France' made of a public head company with daughter companies for the management of power and gas distribution networks, for the management of gas and power transportation networks, for the production and commercialization of electricity, and for the supply and commercialization of gas. This convergence is justified by the multi-energy offer of both EdF and GdF companies and by the other fusions between electric and gas operators observed in the rest of Europe (EON and Ruhrgas for instance). It would also warrant the perenniality of the public utility of energy distribution and the status of the personnel. (J.S.)

  18. Renormalization-group improved inflationary scalar electrodynamics and SU(5) scenarios confronted with Planck 2013 and BICEP2 results

    Science.gov (United States)

    Elizalde, E.; Odintsov, S. D.; Pozdeeva, E. O.; Vernov, S. Yu.

    2014-10-01

    The possibility to construct inflationary models for the renormalization-group (RG) improved potentials corresponding to scalar electrodynamics and to SU(2) and SU(5) models is investigated. In all cases, the tree-level potential, which corresponds to the cosmological constant in the Einstein frame, is seen to be nonsuitable for inflation. Rather than adding the Hilbert-Einstein term to the action, quantum corrections to the potential, coming from the RG equation, are included. The inflationary scenario is analyzed with unstable de Sitter solutions that correspond to positive values of the coupling function, only. We show that, for the finite SU(2) model and SU(2) gauge model, there are no de Sitter solutions suitable for inflation, unless exit from it occurs according to some weird, nonstandard scenarios. Inflation is realized both for scalar electrodynamics and for SU(5) RG-improved potentials, and the corresponding values of the coupling function are seen to be positive. It is shown that, for quite reasonable values of the parameters, the inflationary models obtained both from scalar electrodynamics and from the SU(5) RG-improved potentials are in good agreement with the most recent observational data coming from the Planck 2013 and BICEP2 collaborations.

  19. Application of group-based QSAR on 2-thioxo-4-thiazolidinone for development of potent anti-diabetic compounds

    Science.gov (United States)

    Choudhari, Prafulla; Kumbhar, Santosh; Phalle, Siddharth; Choudhari, Sujata; Desai, Sujit; Khare, Shivratna; Jadhav, Swapnil

    2017-01-01

    To identify the structural requirement for development of lead structures with PPAR gamma binding activity group based quantitative structure activity relationship (GQSAR) studies on 46 reported structures were carried out. The molecules in the current dataset were fragmented into seven functional groups fragments (R1, R2, R3, R4, R5, R6 and R7). GQSAR models were derived using multiple linear regressions analysis. Four generated GQSAR models were selected based on the statistical significance of the model. It was found that the presence of smaller groups on fragment R7 and presence of lipophilic group at fragment R2 was conducive for PPAR gamma binding. Additionally, the existence of hydrogen bond acceptor at fragments R6 was fruitful PPAR gamma binding. The generated models provide a site-specific insight into the structural requirements PPAR γ binding which can be used to design and develop potent antidiabetic compounds.

  20. Propuesta de un programa para la\teducación anti-doping en las escuelas comunitarias de deportes del municipio Pinar del Río

    Directory of Open Access Journals (Sweden)

    Ida Galván Rodríguez

    2009-12-01

    Full Text Available Dada la magnitud que ha cobrado el dopaje en el mundo actual, este sigue siendo un gran problema esencial del deporte moderno a pesar de todas las acciones realizadas, políticas de control y sanciones. Por tal motivo, esta situación debe ser reevaluada desde otras alternativas como la que proponemos en este trabajo. Planteamos un proyecto de Educación Anti-doping para las Escuelas Comunitarias de Deportes en el municipio Pinar del Río pues estas constituyen la institución social encargada de desarrollar funciones educativas de Deporte, Educación Física, Recreación Física y Cultura Física en general, en su territorio. El mismo plantea una serie de objetivos, acciones y actividades, abordadas fundamentalmente en las vertientes extracurricular no formal y extracurricular informal, el cual se respalda en todo un conjunto de consideraciones científico-metodológicas. Finalmente, planteamos útiles recomendaciones que ayuden a generalizar esta alternativa educativa y a profundizar en cómo enriquecer una educación Anti- doping desde la comunidad.