WorldWideScience

Sample records for anonymous nuclear markers

  1. Anonymous and EST-based microsatellite DNA markers that transfer broadly across the fig tree genus (Ficus, Moraceae).

    Science.gov (United States)

    Heer, Katrin; Machado, Carlos A; Himler, Anna G; Herre, Edward Allen; Kalko, Elisabeth K V; Dick, Christopher W

    2012-08-01

    We developed a set of microsatellite markers for broad utility across the species-rich pantropical tree genus Ficus (fig trees). The markers were developed to study population structure, hybridization, and gene flow in neotropical species. We developed seven novel primer sets from expressed sequence tag (EST) libraries of F. citrifolia and F. popenoei (subgen. Urostigma sect. Americana) and optimized five previously developed anonymous loci for cross-species amplification. The markers were successfully tested on four species from the basal subgenus Pharmacosycea sect. Pharmacosycea (F. insipida, F. maxima, F. tonduzii, and F. yoponensis) and seven species of the derived subgenus Urostigma (F. citrifolia, F. colubrinae, F. costaricana, F. nymphaeifolia, F. obtusifolia, F. pertusa, and F. popenoei). The 12 markers amplified consistently and displayed polymorphism in all the species. This set of microsatellite markers is transferable across the phylogenetic breadth of Ficus, and should therefore be useful for studies of population structure and gene flow in approximately 750 fig species worldwide.

  2. Against anonymity.

    Science.gov (United States)

    Baker, Robert

    2014-05-01

    In 'New Threats to Academic Freedom' Francesca Minerva argues that anonymity for the authors of controversial articles is a prerequisite for academic freedom in the Internet age. This argument draws its intellectual and emotional power from the author's account of the reaction to the on-line publication of ' After-birth abortion: why should the baby live?'--an article that provoked cascades of hostile postings and e-mails. Reflecting on these events, Minerva proposes that publishers should offer the authors of controversial articles the option of publishing their articles anonymously. This response reviews the history of anonymous publication and concludes that its reintroduction in the Internet era would recreate problems similar to those that led print journals to abandon the practice: corruption of scholarly discourse by invective and hate speech, masked conflicts of interest, and a diminution of editorial accountability. It also contends that Minerva misreads the intent of the hostile e-mails provoked by 'After-birth abortion,' and that ethicists who publish controversial articles should take responsibility by dialoguing with their critics--even those whose critiques are emotionally charged and hostile. © 2014 John Wiley & Sons Ltd.

  3. A Single Transcriptome of a Green Toad (Bufo viridis Yields Candidate Genes for Sex Determination and -Differentiation and Non-Anonymous Population Genetic Markers.

    Directory of Open Access Journals (Sweden)

    Jörn F Gerchen

    Full Text Available Large genome size, including immense repetitive and non-coding fractions, still present challenges for capacity, bioinformatics and thus affordability of whole genome sequencing in most amphibians. Here, we test the performance of a single transcriptome to understand whether it can provide a cost-efficient resource for species with large unknown genomes. Using RNA from six different tissues from a single Palearctic green toad (Bufo viridis specimen and Hiseq2000, we obtained 22,5 Mio reads and publish >100,000 unigene sequences. To evaluate efficacy and quality, we first use this data to identify green toad specific candidate genes, known from other vertebrates for their role in sex determination and differentiation. Of a list of 37 genes, the transcriptome yielded 32 (87%, many of which providing the first such data for this non-model anuran species. However, for many of these genes, only fragments could be retrieved. In order to allow also applications to population genetics, we further used the transcriptome for the targeted development of 21 non-anonymous microsatellites and tested them in genetic families and backcrosses. Eleven markers were specifically developed to be located on the B. viridis sex chromosomes; for eight markers we can indeed demonstrate sex-specific transmission in genetic families. Depending on phylogenetic distance, several markers, which are sex-linked in green toads, show high cross-amplification success across the anuran phylogeny, involving nine systematic anuran families. Our data support the view that single transcriptome sequencing (based on multiple tissues provides a reliable genomic resource and cost-efficient method for non-model amphibian species with large genome size and, despite limitations, should be considered as long as genome sequencing remains unaffordable for most species.

  4. Development of stable marker-free nuclear transformation strategy ...

    African Journals Online (AJOL)

    To avoid the negative effects caused by the marker genes, we tried to develop a stable marker-free nuclear transformation system in Chlorella. For this, linear gene expression cassettes (LGEC) were constructed with functional domains, which are responsible for transformation, of SV40 large T antigen. The LGECs were ...

  5. Anonymity in voting revisited

    NARCIS (Netherlands)

    Jonker, Hugo; Pieters, Wolter; Chaum, David; Jakobsson, Markus; Rivest, Ronald L.; Ryan, Peter Y.A.; Benaloh, Josh; Kutylowski, Miroslaw; Adida, Ben

    According to international law, anonymity of the voter is a fundamental precondition for democratic elections. In electronic voting, several aspects of voter anonymity have been identified. In this paper, we re-examine anonymity with respect to voting, and generalise existing notions of anonymity in

  6. Supplementary data: Development of nuclear DNA markers for ...

    Indian Academy of Sciences (India)

    Supplementary data: Development of nuclear DNA markers for evolutionary studies in Plasmodium falciparum. Celia Thomas, Sneh Shalini, N. Raghavendra, Meenakshi Choudhary, Anju Verma, Hema Joshi,. A. P. Dash and Aparup Das. J. Genet. 86, 65–68. Primer sequences for amplification of putatively neutral ...

  7. Nuclear medicine markers of tumor oxygenation and radioresistance

    International Nuclear Information System (INIS)

    Chapman, J. Donald; Schneider, R.H.; Stobbe, C.C.; Kim, E.; Engelhardt, E.L.; Coia, L.

    1996-01-01

    Purpose/Objective: The objective of this research project was to synthesize, purify, radiolabel and characterize second-generation nuclear medicine markers of tissue oxygenation with properties superior to iodoazomycin arabinoside (IAZA) and to validate the hypoxia-marking activity of optimal compounds by independent measurements of tumor oxygenation and tumor radioresistance. Materials and Methods: Six hypoxic markers of the iodoazomycin nucleoside class with water solubilities greater than IAZA were synthesized by published procedures. The markers were purified, chemically characterized and labeled with Iodine-125 or Iodine-131. Absolute rates of marker ligation to the macromolecules of hypoxic EMT-6 tumor cells in vitro were determined as a function of marker concentration and used to establish relative marker effectiveness. Hypoxic marking activity in tumors was determined from tumor/blood (T/B) and tumor/muscle (T/M) ratios of radiolabelled marker in EMT-6 tumor-bearing C.B17/Icr scid mice. The optimal marker was administered to R3327-H and R3327-AT tumor-bearing Fischer X Copenhagen rats for estimates of tumor oxygenation by T/B and T/M ratios. Oxygen distributions in the same tumors were obtained with the Eppendorf pO 2 Histograph. The radioresistance of individual tumors was determined from in vitro plating efficiencies of cells released from tumors which had been irradiated in vivo with 20 Gy Cs-137 γ-rays. Results: Of the six iodinated azomycin nucleosides investigated, five were novel markers and all had water solubilities higher than IAZA. Iodinated azomycin xylopyranoside (β-D-IAZXP) was selected as the optimal marker of this class since it 1) exhibited the highest absolute rate of ligation to hypoxic tumor cells in vitro, 2) had the fastest plasma clearance rate in tumor-bearing mice and 3) yielded high T/B ratios in both the mouse and rat tumor models employed in this study. Planar nuclear medicine images of (I-131) β-D-IAZXP in tumor-bearing rats

  8. Data anonymization patent landscape

    OpenAIRE

    Mirjana Pejić Bach; Jasmina Pivar; Ksenija Dumičić

    2017-01-01

    The omnipresent, unstoppable increase in digital data has led to a greater understanding of the importance of data privacy. Different approaches are used to implement data privacy. The goal of this paper is to develop a data anonymization patent landscape, by determining the following: (i) the trend in data anonymization patenting, (ii) the type of technical content protected in data anonymization, (iii) the organizations and countries most active in patenting data anonymization know-how; and...

  9. Anonymous steps: gender and Gamblers Anonymous

    OpenAIRE

    Rogers, Jim

    2015-01-01

    The biggest source of help for problem gamblers remains gamblers anonymous (GA) in terms of accessibility and availability. GA has traditionally been very much a male preserve. This paper reports on a literature review of Gamblers Anonymous together with data from observations of a contemporary open GA meeting over a one year period. Whilst some studies from North America suggest a changing culture and gender balance within GA programmes observations from the North of England, supported b...

  10. Quantum anonymous voting with anonymity check

    International Nuclear Information System (INIS)

    Horoshko, Dmitri; Kilin, Sergei

    2011-01-01

    We propose a new protocol for quantum anonymous voting having serious advantages over the existing protocols: it protects both the voters from a curious tallyman and all the participants from a dishonest voter in unconditional way. The central idea of the protocol is that the ballots are given back to the voters after the voting process, which gives a possibility for two voters to check the anonymity of the vote counting process by preparing a special entangled state of two ballots. Any attempt of cheating from the side of the tallyman results in destroying the entanglement, which can be detected by the voters.

  11. Data anonymization patent landscape

    Directory of Open Access Journals (Sweden)

    Mirjana Pejić Bach

    2017-01-01

    Full Text Available The omnipresent, unstoppable increase in digital data has led to a greater understanding of the importance of data privacy. Different approaches are used to implement data privacy. The goal of this paper is to develop a data anonymization patent landscape, by determining the following: (i the trend in data anonymization patenting, (ii the type of technical content protected in data anonymization, (iii the organizations and countries most active in patenting data anonymization know-how; and (iv the topics emerging most often in patent titles. Patents from the PatSeer database relating to data anonymization from 2001 to 2015 were analyzed. We used the longitudinal approach in combination with text mining techniques to develop a data anonymization patent landscape. The results indicated the following. The number of single patent families is growing with a high increase after 2010, thus indicating a positive trend in the area of patenting data anonymization solutions. The majority of patenting activities relate to the G Physics section. Organizations from the USA and Japan assigned the majority of patents related to data anonymization. The results of text mining indicate that the most often used word in titles of data anonymization patents are “anonym*, “method”, “data” and “system”. Several additional words that indicated the most frequent topics related to data anonymization were: “equipment”, “software”, “protection”, “identification”, or “encryption”, and specific topics such as “community”, “medical”, or “service”.

  12. Distinctively variable sequence-based nuclear DNA markers for multilocus phylogeography of the soybean- and rice-infecting fungal pathogen Rhizoctonia solani AG-1 IA

    Science.gov (United States)

    2009-01-01

    A series of multilocus sequence-based nuclear DNA markers was developed to infer the phylogeographical history of the Basidiomycetous fungal pathogen Rhizoctonia solani AG-1 IA infecting rice and soybean worldwide. The strategy was based on sequencing of cloned genomic DNA fragments (previously used as RFLP probes) and subsequent screening of fungal isolates to detect single nucleotide polymorphisms (SNPs). Ten primer pairs were designed based on these sequences, which resulted in PCR amplification of 200-320 bp size products and polymorphic sequences in all markers analyzed. By direct sequencing we identified both homokaryon and heterokaryon (i.e. dikaryon) isolates at each marker. Cloning the PCR products effectively estimated the allelic phase from heterokaryotic isolates. Information content varied among markers from 0.5 to 5.9 mutations per 100 bp. Thus, the former RFLP codominant probes were successfully converted into six distinctively variable sequence-based nuclear DNA markers. Rather than discarding low polymorphism loci, the combination of these distinctively variable anonymous nuclear markers would constitute an asset for the unbiased estimate of the phylogeographical parameters such as population sizes and divergent times, providing a more reliable species history that shaped the current population structure of R. solani AG-1 IA. PMID:21637462

  13. Anonymous women? Gamblers Anonymous and gender

    OpenAIRE

    Rogers, Jim

    2016-01-01

    One of the rapidly changing elements in gambling environments is the increasing participation of women in many forms of gambling, and the growing proportions of problem gamblers who are female. It is known that women who develop gambling problems differ from men in a range of ways:for example they are more likely to have co-morbidities such as anxiety and depression, and to gamble as an 'escape' from such co-occuring problems. Gamblers Anonymous (GA) has a number of meetings across New Zeala...

  14. Anonymous Connections and Onion Routing

    National Research Council Canada - National Science Library

    Syverson, Paul F; Goldschlag, David M; Reed, Michael G

    1997-01-01

    .... Unmodified Internet applications can use these anonymous connections by means of proxies. The proxies may also make communication anonymous by removing identifying information from the data stream...

  15. Nuclear osteopontin-c is a prognostic breast cancer marker.

    Science.gov (United States)

    Zduniak, K; Ziolkowski, P; Ahlin, C; Agrawal, A; Agrawal, S; Blomqvist, C; Fjällskog, M-L; Weber, G F

    2015-02-17

    Although Osteopontin has been known as a marker for cancer progression, the elevated production of this cytokine is not specific for cancer. We have identified the splice variant Osteopontin-c as being absent from healthy tissue but associated with about 75% of breast cancer cases. However, in previous studies of Osteopontin-c, follow-up information was not available. Here we have analysed 671 patients, comprising a cohort of 291 paraffin blocks plus a population-based case-control study of 380 arrayed breast tumor tissues. We find that high staining intensity of nuclear Osteopontin-c is strongly associated with mortality in patients with early breast cancer. Cytosolic staining for exon 4, reflective of Osteopontin-a and -b also predicts poor outcome. By contrast, total Osteopontin does not correlate with prognosis. These diverse assessments of Osteopontin also do not correlate with each other, suggesting distinct expression patterns for the variant forms. Consistent with its role in tumor progression, not tumor initiation, Osteopontin-c is not correlated with proliferation markers (Ki-67, cyclin A, cyclin B, cyclin E and cyclin D), neither is it correlated with ER, PR or HER2. The addition of Osteopontin-c immunohistochemistry to standard pathology work-ups may have prognostic benefit in early breast cancer diagnosis.

  16. Anonymization of Court Orders

    DEFF Research Database (Denmark)

    Povlsen, Claus; Jongejan, Bart; Hansen, Dorte Haltrup

    We describe an anonymization tool that was commissioned by and specified together with Schultz, a publishing company specialized in Danish law related publications. Unavailability of training data and the need to guarantee compliance with pre-existing anonymization guidelines forced us to implement...... a tool using manually crafted rules. We used Bracmat, a programming language that is specialized in transforming tree data structures, to meet the requirement to pass the XML structure of the input document unscathed through the whole workflow. The tool attains a reassuringly good recall, makes almost...

  17. Anonymous Authentication for Smartcards

    Directory of Open Access Journals (Sweden)

    J. Hajny

    2010-06-01

    Full Text Available The paper presents an innovative solution in the field of RFID (Radio-Frequency IDentification smartcard authentication. Currently the smartcards are used for many purposes - e.g. employee identification, library cards, student cards or even identity credentials. Personal identity is revealed to untrustworthy entities every time we use these cards. Such information could later be used without our knowledge and for harmful reasons like shopping pattern scanning or even movement tracking. We present a communication scheme for keeping one’s identity private in this paper. Although our system provides anonymity, it does not allow users to abuse this feature. The system is based on strong cryptographic primitives that provide features never available before. Besides theoretical design of the anonymous authentication scheme and its analysis we also provide implementation results.

  18. Deniable Anonymous Group Authentication

    Science.gov (United States)

    2014-02-13

    providers, such as Facebook or Twitter, and the use of public-key encryption and linkable ring signatures. Linkable ring signatures [44,45] allow a...2007. [36] R. Henry and I. Goldberg. Batch proofs of partial knowledge. University of Waterloo, Technical report CACR, 2012 . [37] R. Henry and I...CT-RSA, 2006. [41] M. Layouni and H. Vangheluwe. Anonymous k-show credentials. In ’07 EuroPKI, 2007. [42] B. Lee, C. Boyd, E. Dawson, K. Kim, J. Yang

  19. Data from: DISCOMARK: nuclear marker discovery from orthologous sequences using draft genome data

    NARCIS (Netherlands)

    Rutschmann, Sereina; Detering, Harald; Simon, S.; Fredslund, Jakob; Monaghan, Michael T.

    2016-01-01

    High-throughput sequencing has laid the foundation for fast and cost-effective development of phylogenetic markers. Here we present the program discomark, which streamlines the development of nuclear DNA (nDNA) markers from whole-genome (or whole-transcriptome) sequencing data, combining local

  20. Genetic Diversity and Structure of Lolium Species Surveyed on Nuclear Simple Sequence Repeat and Cytoplasmic Markers

    Directory of Open Access Journals (Sweden)

    Hongwei Cai

    2017-04-01

    Full Text Available To assess the genetic diversity and population structure of Lolium species, we used 32 nuclear simple sequence repeat (SSR markers and 7 cytoplasmic gene markers to analyze a total of 357 individuals from 162 accessions of 9 Lolium species. This survey revealed a high level of polymorphism, with an average number of alleles per locus of 23.59 and 5.29 and an average PIC-value of 0.83 and 0.54 for nuclear SSR markers and cytoplasmic gene markers, respectively. Analysis of molecular variance (AMOVA revealed that 16.27 and 16.53% of the total variation was due to differences among species, with the remaining 56.35 and 83.47% due to differences within species and 27.39 and 0% due to differences within individuals in 32 nuclear SSR markers set and 6 chloroplast gene markers set, respectively. The 32 nuclear SSR markers detected three subpopulations among 357 individuals, whereas the 6 chloroplast gene markers revealed three subpopulations among 160 accessions in the STRUCTURE analysis. In the clustering analysis, the three inbred species clustered into a single group, whereas the outbreeding species were clearly divided, especially according to nuclear SSR markers. In addition, almost all Lolium multiflorum populations were clustered into group C4, which could be further divided into three subgroups, whereas Lolium perenne populations primarily clustered into two groups (C2 and C3, with a few lines that instead grouped with L. multiflorum (C4 or Lolium rigidum (C6. Together, these results will useful for the use of Lolium germplasm for improvement and increase the effectiveness of ryegrass breeding.

  1. Development of stable marker-free nuclear transformation strategy ...

    African Journals Online (AJOL)

    Ahmed & Sameh

    Schematic flow diagram for the construction of naked marker-free DNA cassettes. QIAquick Gel Extraction Kit (Qiagen, CA, USA). All PCR reactions were carried out using the high fidelity DNA polymerase (TLA polymerase) (Bioneer, Daejeon, Republic of Korea). Generation of transgenic C. vulgaris by electroporation.

  2. How to Bootstrap Anonymous Communication

    DEFF Research Database (Denmark)

    Jakobsen, Sune K.; Orlandi, Claudio

    2015-01-01

    formal study in this direction. To solve this problem, we introduce the concept of anonymous steganography: think of a leaker Lea who wants to leak a large document to Joe the journalist. Using anonymous steganography Lea can embed this document in innocent looking communication on some popular website...... (such as cat videos on YouTube or funny memes on 9GAG). Then Lea provides Joe with a short key k which, when applied to the entire website, recovers the document while hiding the identity of Lea among the large number of users of the website. Our contributions include: { Introducing and formally dening...... anonymous steganography, { A construction showing that anonymous steganography is possible (which uses recent results in circuits obfuscation), { A lower bound on the number of bits which are needed to bootstrap anonymous communication....

  3. How to Bootstrap Anonymous Communication

    DEFF Research Database (Denmark)

    Jakobsen, Sune K.; Orlandi, Claudio

    2015-01-01

    formal study in this direction. To solve this problem, we introduce the concept of anonymous steganography: think of a leaker Lea who wants to leak a large document to Joe the journalist. Using anonymous steganography Lea can embed this document in innocent looking communication on some popular website...... (such as cat videos on YouTube or funny memes on 9GAG). Then Lea provides Joe with a short key $k$ which, when applied to the entire website, recovers the document while hiding the identity of Lea among the large number of users of the website. Our contributions include: - Introducing and formally...... defining anonymous steganography, - A construction showing that anonymous steganography is possible (which uses recent results in circuits obfuscation), - A lower bound on the number of bits which are needed to bootstrap anonymous communication....

  4. Nuclear stiffness and chromatin condensation as markers for aggressive prostate cancer

    Science.gov (United States)

    Khan, Zeina; Santos, Julianna; Hussain, Fazle

    Previous studies have demonstrated that nuclear rheology parameters - stiffness and fluidity - depend on expression levels of nuclear membrane proteins lamin A/C and lamin B. No quantitative nuclear rheology has been studied to compare cancers of different aggressiveness. Our nuclear creep experiments using a microfluidic channel with a narrow constriction show that aggressive prostate cancer cell nuclei have a lower stiffness than benign cell nuclei; thus nuclear stiffness can be easily used as a cancer malignancy marker. We also find that nuclear stiffness and fluidity, contrary to prior claims, do not strongly depend on lamin A/C or B expression levels of prostate cancer cells. Rather, we find that nuclear stiffness depends on chromatin condensation.

  5. Concept analysis: lack of anonymity.

    Science.gov (United States)

    Swan, Marilyn A; Hobbs, Barbara B

    2017-05-01

    To re-examine and expand understanding of the concept 'lack of anonymity' as a component of rural nursing theory. Early healthcare literature reports lack of anonymity as part of social and working environments, particularly rural nursing. Rural nursing theory included the first published concept analysis on lack of anonymity but lacked empirical referents. Workforce, societal and rural healthcare changes support an updated analysis. To further understand lack of anonymity, its present day use and applicability to diverse environments, research from multiple disciplines was reviewed. Concept analysis. A literature search using eight terms in eleven databases was conducted of literature published between 2008-2013. Walker and Avant's concept analysis methodology guided the analysis. The previous concept analysis is supported in part by current literature. The defining attributes, 'identifiable', 'establishing boundaries for public and private self and interconnectedness' in a community were updated. Updated antecedents include: (i) environmental context; (ii) opportunities to become visible; (iii) developing relationships and (iv) unconscious or limited awareness of public or personal privacy. Consequences are: (i) familiarity; (ii) visibility; (iii) awareness of privacy and (iv) manage or balance of lack of anonymity. Cases were constructed and empirical referents identified. The concept of lack of anonymity was updated; portions of the original definition remain unchanged. Empirical referents reveal the defining attributes in daily life and may guide future research on the effect of lack of anonymity on nursing practice. This analysis advances the conceptual understanding of rural nursing theory. © 2016 John Wiley & Sons Ltd.

  6. On Backward-Style Anonymity Verification

    Science.gov (United States)

    Kawabe, Yoshinobu; Mano, Ken; Sakurada, Hideki; Tsukada, Yasuyuki

    Many Internet services and protocols should guarantee anonymity; for example, an electronic voting system should guarantee to prevent the disclosure of who voted for which candidate. To prove trace anonymity, which is an extension of the formulation of anonymity by Schneider and Sidiropoulos, this paper presents an inductive method based on backward anonymous simulations. We show that the existence of an image-finite backward anonymous simulation implies trace anonymity. We also demonstrate the anonymity verification of an e-voting protocol (the FOO protocol) with our backward anonymous simulation technique. When proving the trace anonymity, this paper employs a computer-assisted verification tool based on a theorem prover.

  7. Anonymous Transactions in Computer Networks

    Science.gov (United States)

    Dolev, Shlomi; Kopeetsky, Marina

    We present schemes for providing anonymous transactions while privacy and anonymity are preserved, providing user anonymous authentication in distributed networks such as the Internet. We first present a practical scheme for anonymous transactions while the transaction resolution is assisted by a Trusted Authority. This practical scheme is extended to a theoretical scheme where a Trusted Authority is not involved in the transaction resolution. Given an authority that generates for each player hard to produce evidence EVID (e. g., problem instance with or without a solution) to each player, the identity of a user U is defined by the ability to prove possession of said evidence. We use Zero-Knowledge proof techniques to repeatedly identify U by providing a proof that U has evidence EVID, without revealing EVID, therefore avoiding identity theft.

  8. RAD-seq derived genome-wide nuclear markers resolve the phylogeny of tunas

    KAUST Repository

    Díaz-Arce, Natalia

    2016-06-07

    Although species from the genus Thunnus include some of the most commercially important and most severely overexploited fishes, the phylogeny of this genus is still unresolved, hampering evolutionary and traceability studies that could help improve conservation and management strategies for these species. Previous attempts based on mitochondrial and nuclear markers were unsuccessful in inferring a congruent and reliable phylogeny, probably due to mitochondrial introgression events and lack of enough phylogenetically informative markers. Here we infer the first genome-wide nuclear marker-based phylogeny of tunas using restriction site associated DNA sequencing (RAD-seq) data. Our results, derived from phylogenomic inferences obtained from 128 nucleotide matrices constructed using alternative data assembly procedures, support a single Thunnus evolutionary history that challenges previous assumptions based on morphological and molecular data.

  9. Markers

    Science.gov (United States)

    Healthy Schools Network, Inc., 2011

    2011-01-01

    Dry erase whiteboards come with toxic dry erase markers and toxic cleaning products. Dry erase markers labeled "nontoxic" are not free of toxic chemicals and can cause health problems. Children are especially vulnerable to environmental health hazards; moreover, schools commonly have problems with indoor air pollution, as they are more densely…

  10. Molecular phylogeny of elasmobranchs inferred from mitochondrial and nuclear markers.

    Science.gov (United States)

    Pavan-Kumar, A; Gireesh-Babu, P; Babu, P P Suresh; Jaiswar, A K; Hari Krishna, V; Prasasd, K Pani; Chaudhari, Aparna; Raje, S G; Chakraborty, S K; Krishna, Gopal; Lakra, W S

    2014-01-01

    The elasmobranchs (sharks, rays and skates) being the extant survivors of one of the earliest offshoots of the vertebrate evolutionary tree are good model organisms to study the primitive vertebrate conditions. They play a significant role in maintaining the ecological balance and have high economic value. Due to over-exploitation and illegal fishing worldwide, the elasmobranch stocks are being decimated at an alarming rate. Appropriate management measures are necessary for restoring depleted elasmobranch stocks. One approach for restoring stocks is implementation of conservation measures and these measures can be formulated effectively by knowing the evolutionary relationship among the elasmobranchs. In this study, a total of 30 species were chosen for molecular phylogeny studies using mitochondrial cytochrome c oxidase subunit I, 12S ribosomal RNA gene and nuclear Internal Transcribed Spacer 2. Among different genes, the combined dataset of COI and 12S rRNA resulted in a well resolved tree topology with significant bootstrap/posterior probabilities values. The results supported the reciprocal monophyly of sharks and batoids. Within Galeomorphii, Heterodontiformes (bullhead sharks) formed as a sister group to Lamniformes (mackerel sharks): Orectolobiformes (carpet sharks) and to Carcharhiniformes (ground sharks). Within batoids, the Myliobatiformes formed a monophyly group while Pristiformes (sawfishes) and Rhinobatiformes (guitar fishes) formed a sister group to all other batoids.

  11. Data Retention and Anonymity Services

    Science.gov (United States)

    Berthold, Stefan; Böhme, Rainer; Köpsell, Stefan

    The recently introduced legislation on data retention to aid prosecuting cyber-related crime in Europe also affects the achievable security of systems for anonymous communication on the Internet. We argue that data retention requires a review of existing security evaluations against a new class of realistic adversary models. In particular, we present theoretical results and first empirical evidence for intersection attacks by law enforcement authorities. The reference architecture for our study is the anonymity service AN.ON, from which we also collect empirical data. Our adversary model reflects an interpretation of the current implementation of the EC Directive on Data Retention in Germany.

  12. Efficient Detection of Novel Nuclear Markers for Brassicaceae by Transcriptome Sequencing.

    Directory of Open Access Journals (Sweden)

    Reinhold Stockenhuber

    Full Text Available The lack of DNA sequence information for most non-model organisms impairs the design of primers that are universally applicable for the study of molecular polymorphisms in nuclear markers. Next-generation sequencing (NGS techniques nowadays provide a powerful approach to overcome this limitation. We present a flexible and inexpensive method to identify large numbers of nuclear primer pairs that amplify in most Brassicaceae species. We first obtained and mapped NGS transcriptome sequencing reads from two of the distantly related Brassicaceae species, Cardamine hirsuta and Arabis alpina, onto the Arabidopsis thaliana reference genome, and then identified short conserved sequence motifs among the three species bioinformatically. From these, primer pairs to amplify coding regions (nuclear protein coding loci, NPCL and exon-primed intron-crossing sequences (EPIC were developed. We identified 2,334 universally applicable primer pairs, targeting 1,164 genes, which provide a large pool of markers as readily usable genomic resource that will help addressing novel questions in the Brassicaceae family. Testing a subset of the newly designed nuclear primer pairs revealed that a great majority yielded a single amplicon in all of the 30 investigated Brassicaceae taxa. Sequence analysis and phylogenetic reconstruction with a subset of these markers on different levels of phylogenetic divergence in the mustard family were compared with previous studies. The results corroborate the usefulness of the newly developed primer pairs, e.g., for phylogenetic analyses or population genetic studies. Thus, our method provides a cost-effective approach for designing nuclear loci across a broad range of taxa and is compatible with current NGS technologies.

  13. "People Are Either Too Fake or Too Real": Opportunities and Challenges in Tie-Based Anonymity

    DEFF Research Database (Denmark)

    Ma, Xiao; Andabili, Nazanin; Barkhuus, Louise

    2017-01-01

    In recent years, several mobile applications allowed individuals to anonymously share information with friends and contacts, without any persistent identity marker. The functions of these “tie-based” anonymity services may be notably different than other social media services. We use semi-structu...

  14. Nuclear ribosomal internal transcribed spacer (ITS) region as a universal DNA barcode marker for Fungi.

    Science.gov (United States)

    Schoch, Conrad L; Seifert, Keith A; Huhndorf, Sabine; Robert, Vincent; Spouge, John L; Levesque, C André; Chen, Wen

    2012-04-17

    Six DNA regions were evaluated as potential DNA barcodes for Fungi, the second largest kingdom of eukaryotic life, by a multinational, multilaboratory consortium. The region of the mitochondrial cytochrome c oxidase subunit 1 used as the animal barcode was excluded as a potential marker, because it is difficult to amplify in fungi, often includes large introns, and can be insufficiently variable. Three subunits from the nuclear ribosomal RNA cistron were compared together with regions of three representative protein-coding genes (largest subunit of RNA polymerase II, second largest subunit of RNA polymerase II, and minichromosome maintenance protein). Although the protein-coding gene regions often had a higher percent of correct identification compared with ribosomal markers, low PCR amplification and sequencing success eliminated them as candidates for a universal fungal barcode. Among the regions of the ribosomal cistron, the internal transcribed spacer (ITS) region has the highest probability of successful identification for the broadest range of fungi, with the most clearly defined barcode gap between inter- and intraspecific variation. The nuclear ribosomal large subunit, a popular phylogenetic marker in certain groups, had superior species resolution in some taxonomic groups, such as the early diverging lineages and the ascomycete yeasts, but was otherwise slightly inferior to the ITS. The nuclear ribosomal small subunit has poor species-level resolution in fungi. ITS will be formally proposed for adoption as the primary fungal barcode marker to the Consortium for the Barcode of Life, with the possibility that supplementary barcodes may be developed for particular narrowly circumscribed taxonomic groups.

  15. Introgression evidence and phylogenetic relationships among three (ParaMisgurnus species as revealed by mitochondrial and nuclear DNA markers

    Directory of Open Access Journals (Sweden)

    Jakovlić I.

    2013-01-01

    Full Text Available The taxonomy of (ParaMisgurnus genera is still debated. We therefore used mitochondrial and nuclear DNA markers to analyze the phylogenetic relationships among Misgurnus anguillicaudatus, Paramisgurnus dabryanus and Misgurnus fossilis. Differing phylogenetic signals from mitochondrial and nuclear marker data suggest an introgression event in the history of M. anguillicaudatus and M. mohoity. No substantial genetic evidence was found that Paramisgurnus dabryanus should be classified as a separate genus.

  16. k-Times Anonymous Authentication

    Science.gov (United States)

    Teranishi, Isamu; Furukawa, Jun; Sako, Kazue

    We propose an authentication scheme in which users can be authenticated anonymously so long as times that they are authenticated is within an allowable number. The proposed scheme has two features: 1) no one, not even an authority, can identify users who have been authenticated within the allowable number, 2) anyone can trace, without help from the authority, dishonest users who have been authenticated beyond the allowable number by using the records of these authentications. Our scheme can be applied to e-voting, e-cash, electronic coupons, and trial browsing of content. In these applications, our scheme, unlike the previous one, conceals users' participation from protocols and guarantees that they will remain anonymous to everyone.

  17. Pattern-Guided k-Anonymity

    OpenAIRE

    Rolf Niedermeier; André Nichterlein; Robert Bredereck

    2013-01-01

    We suggest a user-oriented approach to combinatorial data anonymization. A data matrix is called k-anonymous if every row appears at least k times—the goal of the NP-hard k-ANONYMITY problem then is to make a given matrix k-anonymous by suppressing (blanking out) as few entries as possible. Building on previous work and coping with corresponding deficiencies, we describe an enhanced k-anonymization problem called PATTERN-GUIDED k-ANONYMITY, where the users specify in which combinations suppre...

  18. Anonymous Web Browsing and Hosting

    OpenAIRE

    MANOJ KUMAR; ANUJ RANI

    2013-01-01

    In today’s high tech environment every organization, individual computer users use internet for accessing web data. To maintain high confidentiality and security of the data secure web solutions are required. In this paper we described dedicated anonymous web browsing solutions which makes our browsing faster and secure. Web application which play important role for transferring our secret information including like email need more and more security concerns. This paper also describes that ho...

  19. Genomic Mining of Phylogenetically Informative Nuclear Markers in Bark and Ambrosia Beetles.

    Science.gov (United States)

    Pistone, Dario; Mugu, Sigrid; Jordal, Bjarte Henry

    Deep level insect relationships are generally difficult to resolve, especially within taxa of the most diverse and species rich holometabolous orders. In beetles, the major diversity occurs in the Phytophaga, including charismatic groups such as leaf beetles, longhorn beetles and weevils. Bark and ambrosia beetles are wood boring weevils that contribute 12 percent of the diversity encountered in Curculionidae, one of the largest families of beetles with more than 50000 described species. Phylogenetic resolution in groups of Cretaceous age has proven particularly difficult and requires large quantity of data. In this study, we investigated 100 nuclear genes in order to select a number of markers with low evolutionary rates and high phylogenetic signal. A PCR screening using degenerate primers was applied to 26 different weevil species. We obtained sequences from 57 of the 100 targeted genes. Sequences from each nuclear marker were aligned and examined for detecting multiple copies, pseudogenes and introns. Phylogenetic informativeness (PI) and the capacity for reconstruction of previously established phylogenetic relationships were used as proxies for selecting a subset of the 57 amplified genes. Finally, we selected 16 markers suitable for large-scale phylogenetics of Scolytinae and related weevil taxa.

  20. Genomic Mining of Phylogenetically Informative Nuclear Markers in Bark and Ambrosia Beetles.

    Directory of Open Access Journals (Sweden)

    Dario Pistone

    Full Text Available Deep level insect relationships are generally difficult to resolve, especially within taxa of the most diverse and species rich holometabolous orders. In beetles, the major diversity occurs in the Phytophaga, including charismatic groups such as leaf beetles, longhorn beetles and weevils. Bark and ambrosia beetles are wood boring weevils that contribute 12 percent of the diversity encountered in Curculionidae, one of the largest families of beetles with more than 50000 described species. Phylogenetic resolution in groups of Cretaceous age has proven particularly difficult and requires large quantity of data. In this study, we investigated 100 nuclear genes in order to select a number of markers with low evolutionary rates and high phylogenetic signal. A PCR screening using degenerate primers was applied to 26 different weevil species. We obtained sequences from 57 of the 100 targeted genes. Sequences from each nuclear marker were aligned and examined for detecting multiple copies, pseudogenes and introns. Phylogenetic informativeness (PI and the capacity for reconstruction of previously established phylogenetic relationships were used as proxies for selecting a subset of the 57 amplified genes. Finally, we selected 16 markers suitable for large-scale phylogenetics of Scolytinae and related weevil taxa.

  1. Revocable Anonymous Access to the Internet?

    Science.gov (United States)

    Claessens, Joris; Diaz, Claudia; Goemans, Caroline; Preneel, Bart; Vandewalle, Joos; Dumortier, Jos

    2003-01-01

    Users of telecommunications networks are concerned about privacy, and desire anonymous access, while some organizations are concerned about how this anonymous access might be abused. Proposes a solution for revocable anonymous access to the Internet. Presents some legal background and motivation for such a solution. Indicates some difficulties and…

  2. Anonymous Boh avatud kunsti maastikul / Raivo Kelomees

    Index Scriptorium Estoniae

    Kelomees, Raivo, 1960-

    2010-01-01

    Anonymous Bohi näitus Tartu Kunstimajas, avatud 30. juulini 2010. Anonymous Boh on koos Non Grataga läbi viinud performance´id Euroopas, Ameerikas ja Aasias. Anonymous Bohi vastused oma näituse ja loominguga seotud küsimustele

  3. Taxonomic confirmation of mud crab species (genus Scylla) in Bangladesh by nuclear and mitochondrial DNA markers.

    Science.gov (United States)

    Sarower, Mohammed Golam; Shahriar, Sheik Istiak Md; Nakamura, Hiromasa; Rouf, Muhammad Abdur; Okada, Shigeru

    2017-11-01

    Taxonomy of mud crabs genus Scylla has been misidentified for several years due to their high morphological plasticity. Several reports concerning mud crab have been published with misleading identification in Bangladesh. In this study, partial fragments of nuclear and mitochondrial DNA of Scylla species obtained from four locations along the Bangladesh coast were used to resolve taxonomical ambiguity of mud crab species. A single PCR product from the nuclear first internal transcribed spacer (ITS-1) marker and phylogenetic trees constructed based on 16S rDNA sequences indicated that all Scylla species obtained in this study were S. olivacea. Both molecular data and morphological characters revealed that S. olivacea is the only major species in Bangladesh coastal waters. Further, the 16S rDNA haplotypes significantly differed with known S. serrata by 33%. From this study it is clear that 'S. serrata' commonly reported from Bangladesh should be S. olivacea.

  4. An Anonymous Credit Card System

    Science.gov (United States)

    Androulaki, Elli; Bellovin, Steven

    Credit cards have many important benefits; however, these same benefits often carry with them many privacy concerns. In particular, the need for users to be able to monitor their own transactions, as well as bank’s need to justify its payment requests from cardholders, entitle the latter to maintain a detailed log of all transactions its credit card customers were involved in. A bank can thus build a profile of each cardholder even without the latter’s consent. In this paper, we present a practical and accountable anonymous credit system based on ecash, with a privacy preserving mechanism for error correction and expense-reporting.

  5. Transcriptome-mining for single-copy nuclear markers in ferns.

    Directory of Open Access Journals (Sweden)

    Carl J Rothfels

    Full Text Available BACKGROUND: Molecular phylogenetic investigations have revolutionized our understanding of the evolutionary history of ferns-the second-most species-rich major group of vascular plants, and the sister clade to seed plants. The general absence of genomic resources available for this important group of plants, however, has resulted in the strong dependence of these studies on plastid data; nuclear or mitochondrial data have been rarely used. In this study, we utilize transcriptome data to design primers for nuclear markers for use in studies of fern evolutionary biology, and demonstrate the utility of these markers across the largest order of ferns, the Polypodiales. PRINCIPAL FINDINGS: We present 20 novel single-copy nuclear regions, across 10 distinct protein-coding genes: ApPEFP_C, cryptochrome 2, cryptochrome 4, DET1, gapCpSh, IBR3, pgiC, SQD1, TPLATE, and transducin. These loci, individually and in combination, show strong resolving power across the Polypodiales phylogeny, and are readily amplified and sequenced from our genomic DNA test set (from 15 diploid Polypodiales species. For each region, we also present transcriptome alignments of the focal locus and related paralogs-curated broadly across ferns-that will allow researchers to develop their own primer sets for fern taxa outside of the Polypodiales. Analyses of sequence data generated from our genomic DNA test set reveal strong effects of partitioning schemes on support levels and, to a much lesser extent, on topology. A model partitioned by codon position is strongly favored, and analyses of the combined data yield a Polypodiales phylogeny that is well-supported and consistent with earlier studies of this group. CONCLUSIONS: The 20 single-copy regions presented here more than triple the single-copy nuclear regions available for use in ferns. They provide a much-needed opportunity to assess plastid-derived hypotheses of relationships within the ferns, and increase our capacity to

  6. Increased nuclear ?-catenin expression in oral potentially malignant lesions: A marker of epithelial dysplasia

    Science.gov (United States)

    Rojas-Alcayaga, Gonzalo; Maturana, Andrea; Aitken, Juan-Pablo; Rojas, Carolina; Ortega, Ana-Verónica

    2015-01-01

    Background Deregulation of ?-catenin is associated with malignant transformation; however, its relationship with potentially malignant and malignant oral processes is not fully understood. The aim of this study was to determine and compare the nuclear ?-catenin expression in oral dysplasia and oral squamous cell carcinoma (OSCC). Material and Methods Cross sectional study. Immunodetection of ?-catenin was performed on 72 samples, with the following distribution: 21 mild dysplasia, 12 moderate dysplasia, severe dysplasia 3, 36 OSCC including 19 well differentiated, 15 moderately differentiated and 2 poorly differentiated. Through microscopic observation the number of positive cells per 1000 epithelial cells was counted. For the statistical analysis, the Kruskal Wallis test was used. Results Nuclear expression of ?-catenin was observed in all samples with severe and moderate dysplasia, with a median of 267.5, in comparison to mild dysplasia whose median was 103.75. Only 10 samples (27.7%) with OSCC showed nuclear expression, with statistically significant differences between groups (p < 0.05). Conclusions Our results are consistent with most of the reports which show increased presence of ?-catenin in severe and moderate dysplasia compared to mild dysplasia; however the expression of nuclear ?-catenin decreased after starting the invasive neoplastic process. This suggests a role for this protein in the progression of dysplasia and early malignant transformation to OSCC. Immunodetection of ?-catenin could be a possible immune marker in the detection of oral dysplasia. Key words:Oral squamous cell carcinoma (OSCC), ?-catenin, oral dysplasia. PMID:26241451

  7. Increased nuclear β-catenin expression in oral potentially malignant lesions: A marker of epithelial dysplasia.

    Science.gov (United States)

    Reyes, Montserrat; Rojas-Alcayaga, Gonzalo; Maturana, Andrea; Aitken, Juan-Pablo; Rojas, Carolina; Ortega, Ana-Verónica

    2015-09-01

    Deregulation of β-catenin is associated with malignant transformation; however, its relationship with potentially malignant and malignant oral processes is not fully understood. The aim of this study was to determine and compare the nuclear β-catenin expression in oral dysplasia and oral squamous cell carcinoma (OSCC). Cross sectional study. Immunodetection of β-catenin was performed on 72 samples, with the following distribution: 21 mild dysplasia, 12 moderate dysplasia, severe dysplasia 3, 36 OSCC including 19 well differentiated, 15 moderately differentiated and 2 poorly differentiated. Through microscopic observation the number of positive cells per 1000 epithelial cells was counted. For the statistical analysis, the Kruskal Wallis test was used. Nuclear expression of β-catenin was observed in all samples with severe and moderate dysplasia, with a median of 267.5, in comparison to mild dysplasia whose median was 103.75. Only 10 samples (27.7%) with OSCC showed nuclear expression, with statistically significant differences between groups (p < 0.05). Our results are consistent with most of the reports which show increased presence of β-catenin in severe and moderate dysplasia compared to mild dysplasia; however the expression of nuclear β-catenin decreased after starting the invasive neoplastic process. This suggests a role for this protein in the progression of dysplasia and early malignant transformation to OSCC. Immunodetection of β-catenin could be a possible immune marker in the detection of oral dysplasia.

  8. Protecting privacy using k-anonymity.

    Science.gov (United States)

    El Emam, Khaled; Dankar, Fida Kamal

    2008-01-01

    There is increasing pressure to share health information and even make it publicly available. However, such disclosures of personal health information raise serious privacy concerns. To alleviate such concerns, it is possible to anonymize the data before disclosure. One popular anonymization approach is k-anonymity. There have been no evaluations of the actual re-identification probability of k-anonymized data sets. Through a simulation, we evaluated the re-identification risk of k-anonymization and three different improvements on three large data sets. Re-identification probability is measured under two different re-identification scenarios. Information loss is measured by the commonly used discernability metric. For one of the re-identification scenarios, k-Anonymity consistently over-anonymizes data sets, with this over-anonymization being most pronounced with small sampling fractions. Over-anonymization results in excessive distortions to the data (i.e., high information loss), making the data less useful for subsequent analysis. We found that a hypothesis testing approach provided the best control over re-identification risk and reduces the extent of information loss compared to baseline k-anonymity. Guidelines are provided on when to use the hypothesis testing approach instead of baseline k-anonymity.

  9. Comparing Random-based and k-Anonymity-Based Algorithms for Graph Anonymization

    OpenAIRE

    Casas Roma, Jordi; Torra, Vicenç; Herrera Joancomartí, Jordi

    2012-01-01

    Recently, several anonymization algorithms have appeared for privacy preservation on graphs. Some of them are based on random- ization techniques and on k-anonymity concepts. We can use both of them to obtain an anonymized graph with a given k-anonymity value. In this paper we compare algorithms based on both techniques in order to obtain an anonymized graph with a desired k-anonymity value. We want to analyze the complexity of these methods to generate anonymized graphs and the quality...

  10. Iberian red deer: paraphyletic nature at mtDNA but nuclear markers support its genetic identity.

    Science.gov (United States)

    Carranza, Juan; Salinas, María; de Andrés, Damián; Pérez-González, Javier

    2016-02-01

    Red deer populations in the Iberian glacial refugium were the main source for postglacial recolonization and subspecific radiation in north-western Europe. However, the phylogenetic history of Iberian red deer (Cervus elaphus hispanicus) and its relationships with northern European populations remain uncertain. Here, we study DNA sequences at the mitochondrial control region along with STR markers for over 680 specimens from all the main red deer populations in Spain and other west European areas. Our results from mitochondrial and genomic DNA show contrasting patterns, likely related to the nature of these types of DNA markers and their specific processes of change over time. The results, taken together, bring support to two distinct, cryptic maternal lineages for Iberian red deer that predated the last glacial maximum and that have maintained geographically well differentiated until present. Haplotype relationships show that only one of them contributed to the northern postglacial recolonization. However, allele frequencies of nuclear markers evidenced one main differentiation between Iberian and northern European subspecies although also supported the structure of both matrilines within Iberia. Thus, our findings reveal a paraphyletic nature for Iberian red deer but also its genetic identity and differentiation with respect to northern subspecies. Finally, we suggest that maintaining the singularity of Iberian red deer requires preventing not only restocking practices with red deer specimens belonging to other European populations but also translocations between both Iberian lineages.

  11. Are both sympatric species Ilex perado and Ilex canariensis secretly hybridizing? Indication from nuclear markers collected in Tenerife

    Directory of Open Access Journals (Sweden)

    Manen Jean-François

    2004-11-01

    Full Text Available Abstract Background Intra-specific and intra-individual polymorphism is frequently observed in nuclear markers of Ilex (Aquifoliaceae and discrepancy between plastid and nuclear phylogenies is the rule in this genus. These observations suggest that inter-specific plastid or/and nuclear introgression played an important role in the process of evolution of Ilex. With the aim of a precise understanding of the evolution of this genus, two distantly related sympatric species collected in Tenerife (Canary Islands, I. perado and I. canariensis, were studied in detail. Introgression between these two species was previously never reported. One plastid marker (the atpB-rbcL spacer and two nuclear markers, the ribosomal internal transcribed spacer (ITS and the nuclear encoded plastid glutamine synthetase (nepGS were analyzed for 13 and 27 individuals of I. perado and I. canariensis, respectively. Results The plastid marker is intra-specifically constant and correlated with species identity. On the other hand, whereas the nuclear markers are conserved in I. perado, they are highly polymorphic in I. canariensis. The presence of pseudogenes and recombination in ITS sequences of I. canariensis explain this polymorphism. Ancestral sequence polymorphism with incomplete lineage sorting, or past or recent hybridization with an unknown species could explain this polymorphism, not resolved by concerted evolution. However, as already reported for many other plants, past or recent introgression of an alien genotype seem the most probable explanation for such a tremendous polymorphism. Conclusions Data do not allow the determination with certitude of the putative species introgressing I. canariensis, but I. perado is suspected. The introgression would be unilateral, with I. perado as the male donor, and the paternal sequences would be rapidly converted in highly divergent and consequently unidentifiable pseudogenes. At least, this study allows the establishment of

  12. Testing a short nuclear marker for inferring staphylinid beetle diversity in an African tropical rain forest.

    Directory of Open Access Journals (Sweden)

    Birthe Thormann

    2011-03-01

    Full Text Available The use of DNA based methods for assessing biodiversity has become increasingly common during the last years. Especially in speciose biomes as tropical rain forests and/or in hyperdiverse or understudied taxa they may efficiently complement morphological approaches. The most successful molecular approach in this field is DNA barcoding based on cytochrome c oxidase I (COI marker, but other markers are used as well. Whereas most studies aim at identifying or describing species, there are only few attempts to use DNA markers for inventorying all animal species found in environmental samples to describe variations of biodiversity patterns.In this study, an analysis of the nuclear D3 region of the 28S rRNA gene to delimit species-like units is compared to results based on distinction of morphospecies. Data derived from both approaches are used to assess diversity and composition of staphylinid beetle communities of a Guineo-Congolian rain forest in Kenya. Beetles were collected with a standardized sampling design across six transects in primary and secondary forests using pitfall traps. Sequences could be obtained of 99% of all individuals. In total, 76 molecular operational taxonomic units (MOTUs were found in contrast to 70 discernible morphospecies. Despite this difference both approaches revealed highly similar biodiversity patterns, with species richness being equal in primary and secondary forests, but with divergent species communities in different habitats. The D3-MOTU approach proved to be an efficient tool for biodiversity analyses.Our data illustrate that the use of MOTUs as a proxy for species can provide an alternative to morphospecies identification for the analysis of changes in community structure of hyperdiverse insect taxa. The efficient amplification of the D3-marker and the ability of the D3-MOTUs to reveal similar biodiversity patterns as analyses of morphospecies recommend its use in future molecular studies on biodiversity.

  13. Pattern-Guided k-Anonymity

    Directory of Open Access Journals (Sweden)

    Rolf Niedermeier

    2013-10-01

    Full Text Available We suggest a user-oriented approach to combinatorial data anonymization. A data matrix is called k-anonymous if every row appears at least k times—the goal of the NP-hard k-ANONYMITY problem then is to make a given matrix k-anonymous by suppressing (blanking out as few entries as possible. Building on previous work and coping with corresponding deficiencies, we describe an enhanced k-anonymization problem called PATTERN-GUIDED k-ANONYMITY, where the users specify in which combinations suppressions may occur. In this way, the user of the anonymized data can express the differing importance of various data features. We show that PATTERN-GUIDED k-ANONYMITY is NP-hard. We complement this by a fixed-parameter tractability result based on a “data-driven parameterization” and, based on this, develop an exact integer linear program (ILP-based solution method, as well as a simple, but very effective, greedy heuristic. Experiments on several real-world datasets show that our heuristic easily matches up to the established “Mondrian” algorithm for k-ANONYMITY in terms of the quality of the anonymization and outperforms it in terms of running time.

  14. Genome- and transcriptome-assisted development of nuclear insertion/deletion markers for Calanus species (Copepoda: Calanoida) identification

    DEFF Research Database (Denmark)

    Smolina, I.; Kollias, S.; Poortvliet, M.

    2014-01-01

    Copepods of the genus Calanus are key zooplankton species in temperate to arctic marine ecosystems. Despite their ecological importance, species identification remains challenging. Furthermore, the recent report of hybrids among Calanus species highlights the need for diagnostic nuclear markers t......-specific amplicon length. Furthermore, most of the markers were successfully amplified in other Calanus species, allowing the molecular identification of Calanus helgolandicus, Calanus hyperboreus and Calanus marshallae...

  15. Automatic Control of Configuration of Web Anonymization

    OpenAIRE

    Tomas Sochor

    2013-01-01

    Anonymization of the Internet traffic usually hides details about the request originator from the target server. Such a disguise might be required in some situations, especially in the case of web browsing. Although the web traffic anonymization is not a part of the http specification, it could be achieved using a certain extra tool. Significant deceleration of anonymized traffic compared to normal traffic is inevitable but it can be controlled in some cases as this article suggests. The resu...

  16. Nuclear translocation of glutathione transferase omega is a progression marker in Barrett's esophagus

    DEFF Research Database (Denmark)

    Piaggi, Simona; Marchi, Santino; Ciancia, Eugenio

    2009-01-01

    Barrett's esophagus (BE) represents a major risk factor for esophageal adenocarcinoma (AC). For this reason, patients with BE are subjected to a systematic endoscopic surveillance to detect initial evolution towards non-invasive neoplasia (NiN) and cancer, that eventually occurs only in a small...... fraction of BE patients. This study was aimed to investigate the possible role of glutathione-S-transferase-omega 1 (GSTO1), a recently discovered member of the glutathione-S-transferase family, as a progression marker in the Barrett's disease in order to improve the diagnosis of Ni......N in BE and to understand the mechanisms of the progression from BE to AC. We investigated the expression and subcellular localization of GSTO1 in biopsies from patients with BE and in human cancer cell lines subjected to heath shock treatment. A selective nuclear localisation of GSTO1 was found in 16/16 biopsies with low...

  17. The genetic profiles of two salmonid populations from Romania obtained through nuclear markers analysis

    Directory of Open Access Journals (Sweden)

    Ramona Nechifor

    2017-05-01

    Full Text Available The Salmonidae fish family is well represented in Romanian fauna, with a total of six species in the wild and reared in fish farms. Among them, the brown trout (Salmo trutta fario can be found in all major Romanian river basins. However, anthropogenic activities might disrupt salmonids’ habitats, so that inbreeding and genetic isolation might easily occur in the wild populations. We analyzed two wild brown trout populations from rivers targeted by anthropogenic activities, by using nuclear markers and genotyping in order to observe their genetic structure. We analyzed nine microsatellites and we observed their alleles frequencies, number of private alleles, observed and expected heterozygosity, as well as their population structure. The two populations are not in Hardy-Weinberg equilibrium for most of the loci and the inbreeding coefficient for both populations suggests a heterozygote deficit. Further sequencing data are needed in order to have a better view upon their complete genetic structure.

  18. Development and characterization of 79 nuclear markers amplifying in viviparous and oviparous clades of the European common lizard.

    Science.gov (United States)

    Horreo, J L; Peláez, M L; Suárez, T; Fitze, P S

    2018-02-01

    The European common lizard (Zootoca vivipara) is a widely distributed species across Europe and Asia exhibiting two reproductive modes (oviparity/viviparity), six major lineages and several sublineages. It has been used to tackle a large variety of research questions, nevertheless, few nuclear DNA sequence markers have been developed for this species. Here we developed 79 new nuclear DNA sequence markers using a clonation protocol. These markers were amplified in several oviparous and viviparous specimens including samples of all extant clades, to test the amplification success and their diversity. 49.4% of the markers were polymorphic and of those, 51.3% amplified in all and 94.9% amplified in 5-7 of the extant Z. vivipara clades. These new markers will be very useful for the study of the population structure, population dynamics, and micro/macro evolution of Z. vivipara. Cross-species amplification in four lizard species (Psammodromus edwardsianus, Podarcis muralis, Lacerta bilineata, and Takydromus sexlineatus) was positive in several of the markers, and six makers amplified in all five species. The large genetic distance between P. edwardsianus and Z. vivipara further suggests that these markers may as well be employed in many other species.

  19. Practical anonymity hiding in plain sight online

    CERN Document Server

    Loshin, Peter

    2013-01-01

    For those with legitimate reason to use the Internet anonymously--diplomats, military and other government agencies, journalists, political activists, IT professionals, law enforcement personnel, political refugees and others--anonymous networking provides an invaluable tool, and many good reasons that anonymity can serve a very important purpose. Anonymous use of the Internet is made difficult by the many websites that know everything about us, by the cookies and ad networks, IP-logging ISPs, even nosy officials may get involved. It is no longer possible to turn off browser cookies to be l

  20. Multilocus nuclear DNA markers reveal population structure and demography of Anopheles minimus.

    Science.gov (United States)

    Dixit, Jyotsana; Arunyawat, Uraiwan; Huong, Ngo Thi; Das, Aparup

    2014-11-01

    Utilization of multiple putatively neutral DNA markers for inferring evolutionary history of species population is considered to be the most robust approach. Molecular population genetic studies have been conducted in many species of Anopheles genus, but studies based on single nucleotide polymorphism (SNP) data are still very scarce. Anopheles minimus is one of the principal malaria vectors of Southeast (SE) Asia including the Northeastern (NE) India. Although population genetic studies with mitochondrial genetic variation data have been utilized to infer phylogeography of the SE Asian populations of this species, limited information on the population structure and demography of Indian An. minimus is available. We herewith have developed multilocus nuclear genetic approach with SNP markers located in X chromosome of An. minimus in eight Indian and two SE Asian population samples (121 individual mosquitoes in total) to infer population history and test several hypotheses on the phylogeography of this species. While the Thai population sample of An. minimus presented the highest nucleotide diversity, majority of the Indian samples were also fairly diverse. In general, An. minimus populations were moderately substructured in the distribution range covering SE Asia and NE India, largely falling under three distinct genetic clusters. Moreover, demographic expansion events could be detected in the majority of the presently studied populations of An. minimus. Additional DNA sequencing of the mitochondrial COII region in a subset of the samples (40 individual mosquitoes) corroborated the existing hypothesis of Indian An. minimus falling under the earlier reported mitochondrial lineage B. © 2014 John Wiley & Sons Ltd.

  1. Is it OK to be an Anonymous?

    NARCIS (Netherlands)

    Serracino Inglott, P.

    2013-01-01

    Do the deviant acts carried out by the collective known as Anonymous qualify as vigilante activity, and if so, can they be justified? Addressing this question helps expose the difficulties of morally evaluating technologically enabled deviance. Anonymous is a complex, fluid actor but not as

  2. Atheists, agnostics and Alcoholics Anonymous.

    Science.gov (United States)

    Tonigan, J Scott; Miller, W R; Schermer, Carol

    2002-09-01

    In spite of the strong emphasis in AA on spiritual beliefs and practices, findings are mixed about the importance of such beliefs in predicting AA affiliation. This study of the Project MATCH outpatient (N = 952) and aftercare (N = 774) samples tested three hypotheses about the role of client God belief and subsequent AA attendance and benefit, taking into account that some individuals may, in fact, deny the existence of a God. Longitudinal analyses were conducted (N = 1,526) investigating client God beliefs, AA attendance, patterns of AA attendance and alcohol use. Assessments were conducted at intake and in 3-month intervals using the Form 90, Religious Behaviors and Background, and the Alcoholics Anonymous Inventory. 12-Step treatment was significantly more likely to promote pre-post shifts in client God beliefs, and atheist and agnostic clients attended AA significantly less often throughout follow-up relative to clients self-labeled as spiritual and religious. AA attendance, however, was significantly associated with increased abstinence and reductions in drinking intensity regardless of God belief. Finally, no differences in percent days abstinence and drinking intensity were found between atheist and agnostic versus spiritual and religious clients, but clients unsure about their God belief reported significantly higher drinking frequency relative to the other groups. God belief appears to be relatively unimportant in deriving AA-related benefit, but atheist and agnostic clients are less likely to initiate and sustain AA attendance relative to spiritual and religious clients. This apparent reticence to affiliate with AA ought to be clinically recognized when encouraging AA participation.

  3. The selective adaptation of the alcoholics anonymous program by Gamblers Anonymous.

    Science.gov (United States)

    Browne, B R

    1991-09-01

    This paper is largely based on a year long observation study of Gamblers Anonymous and Alcoholics Anonymous meetings in northern California. The paper argues, contrary to popular assumption, that Gamblers Anonymous is significantly different from Alcoholics Anonymous. Differences, in members' consciousness for example, are discussed. The paper contends that although there is some12 step consciousness in G.A., the dominant consciousness ispage 17 consciousness. The significant differences are attributed to the selective adaptation of the Alcoholics Anonymous program. Several consequences of these differences, such as the central role of a language of the self in A.A. and not in G.A., are highlighted.

  4. Purpose-restricted Anonymous Mobile Communications Using Anonymous Signatures in Online Credential Systems

    DEFF Research Database (Denmark)

    Fathi, Hanane; Shin, SeongHan; Kobara, Kazukuni

    2010-01-01

    To avoid the risk of long-term storage of secrets on a portable device, an online credential system supports the roaming user in retrieving securely at various locations his private key and other material to generate anonymous signatures. The protocol proposed here allows a roaming mobile user...... to access anonymously services such as whistle blowing and net-counselling. Our approach: (1) allows a mobile user, remembering a short password, to anonymously and securely retrieve the credentials necessary for his anonymous communication without assuming a pre-established anonymous channel...

  5. The nuclear elongation factor-1α gene: a promising marker for phylogenetic studies of Triatominae (Hemiptera: Reduviidae).

    Science.gov (United States)

    Díaz, Sebastián; Triana-Chávez, Omar; Gómez-Palacio, Andrés

    2016-09-01

    Molecular systematics is a remarkable approach for understanding the taxonomic traits and allows the exploration of the inter-population dynamics of several species in the Triatominae subfamily that are involved in Trypanosoma cruzi transmission. Compared to other relevant species that transmit vector-borne diseases, such as some species of the Diptera, there are relatively few nuclear genetic markers available for systematic studies in the Triatominae subfamily. Molecular systematic studies performed on Triatominae are based on mitochondrial gene fragments and, less frequently, on nuclear ribosomal genes or spacers. Due to the fact that these markers can occasionally present problems such as nuclear mitochondrial genes (NUMTs) or intra-genomic variation for high gene copy numbers, it is necessary to use additional nuclear markers to more reliably address the molecular evolution of Triatominae. In this study, we performed phylogenetic analysis using the nuclear elongation factor-1 alpha (EF-1α) gene in individuals from 12 species belonging to the Triatomini and Rhodniini tribes. Genetic diversities and phylogenetic topologies were compared with those obtained for the mitochondrial 16S rRNA and Cytochrome b (cyt b) genes, as well as for the D2 variable region of the ribosomal 28S rRNA gene. These results indicate that the EF-1α marker exhibits an intermediate level of diversity compared to mitochondrial and nuclear ribosomal genes, and that phylogenetic analysis based on EF-1α is highly informative for resolving deep phylogenetic relationships in Triatominae, such as tribe or genera. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Phylogenetic origin of limes and lemons revealed by cytoplasmic and nuclear markers.

    Science.gov (United States)

    Curk, Franck; Ollitrault, Frédérique; Garcia-Lor, Andres; Luro, François; Navarro, Luis; Ollitrault, Patrick

    2016-04-01

    The origin of limes and lemons has been a source of conflicting taxonomic opinions. Biochemical studies, numerical taxonomy and recent molecular studies suggested that cultivated Citrus species result from interspecific hybridization between four basic taxa (C. reticulata,C. maxima,C. medica and C. micrantha). However, the origin of most lemons and limes remains controversial or unknown. The aim of this study was to perform extended analyses of the diversity, genetic structure and origin of limes and lemons. The study was based on 133 Citrus accessions. It combined maternal phylogeny studies based on mitochondrial and chloroplastic markers, and nuclear structure analysis based on the evaluation of ploidy level and the use of 123 markers, including 73 basic taxa diagnostic single nucleotide polymorphism (SNP) and indel markers. The lime and lemon horticultural group appears to be highly polymorphic, with diploid, triploid and tetraploid varieties, and to result from many independent reticulation events which defined the sub-groups. Maternal phylogeny involves four cytoplasmic types out of the six encountered in the Citrus genus. All lime and lemon accessions were highly heterozygous, with interspecific admixture of two, three and even the four ancestral taxa genomes. Molecular polymorphism between varieties of the same sub-group was very low. Citrus medica contributed to all limes and lemons and was the direct male parent for the main sub-groups in combination with C. micrantha or close papeda species (for C. aurata, C. excelsa, C. macrophylla and C. aurantifolia--'Mexican' lime types of Tanaka's taxa), C. reticulata(for C. limonia, C. karna and C. jambhiri varieties of Tanaka's taxa, including popular citrus rootstocks such as 'Rangpur' lime, 'Volkamer' and 'Rough' lemons), C. aurantium (for C. limetta and C. limon--yellow lemon types--varieties of Tanaka's taxa) or the C. maxima × C. reticulate hybrid (for C. limettioides--'Palestine sweet' lime types--and C

  7. A flexible approach to distributed data anonymization.

    Science.gov (United States)

    Kohlmayer, Florian; Prasser, Fabian; Eckert, Claudia; Kuhn, Klaus A

    2014-08-01

    Sensitive biomedical data is often collected from distributed sources, involving different information systems and different organizational units. Local autonomy and legal reasons lead to the need of privacy preserving integration concepts. In this article, we focus on anonymization, which plays an important role for the re-use of clinical data and for the sharing of research data. We present a flexible solution for anonymizing distributed data in the semi-honest model. Prior to the anonymization procedure, an encrypted global view of the dataset is constructed by means of a secure multi-party computing (SMC) protocol. This global representation can then be anonymized. Our approach is not limited to specific anonymization algorithms but provides pre- and postprocessing for a broad spectrum of algorithms and many privacy criteria. We present an extensive analytical and experimental evaluation and discuss which types of methods and criteria are supported. Our prototype demonstrates the approach by implementing k-anonymity, ℓ-diversity, t-closeness and δ-presence with a globally optimal de-identification method in horizontally and vertically distributed setups. The experiments show that our method provides highly competitive performance and offers a practical and flexible solution for anonymizing distributed biomedical datasets. Copyright © 2013 Elsevier Inc. All rights reserved.

  8. A Mechanism for Anonymous Credit Card Systems

    Science.gov (United States)

    Tamura, Shinsuke; Yanase, Tatsuro

    This paper proposes a mechanism for anonymous credit card systems, in which each credit card holder can conceal individual transactions from the credit card company, while enabling the credit card company to calculate the total expenditures of transactions of individual card holders during specified periods, and to identify card holders who executed dishonest transactions. Based on three existing mechanisms, i.e. anonymous authentication, blind signature and secure statistical data gathering, together with implicit transaction links proposed here, the proposed mechanism enables development of anonymous credit card systems without assuming any absolutely trustworthy entity like tamper resistant devices or organizations faithful both to the credit card company and card holders.

  9. Nuclear markers reveal a complex introgression pattern among marine turtle species on the Brazilian coast.

    Science.gov (United States)

    Vilaça, Sibelle T; Vargas, Sarah M; Lara-Ruiz, Paula; Molfetti, Érica; Reis, Estéfane C; Lôbo-Hajdu, Gisele; Soares, Luciano S; Santos, Fabrício R

    2012-09-01

    Surprisingly, a high frequency of interspecific sea turtle hybrids has been previously recorded in a nesting site along a short stretch of the Brazilian coast. Mitochondrial DNA data indicated that as much as 43% of the females identified as Eretmochelys imbricata are hybrids in this area (Bahia State of Brazil). It is a remarkable find, because most of the nesting sites surveyed worldwide, including some in northern Brazil, presents no hybrids, and rare Caribbean sites present no more than 2% of hybrids. Thus, a detailed understanding of the hybridization process is needed to evaluate natural or anthropogenic causes of this regional phenomenon in Brazil, which could be an important factor affecting the conservation of this population. We analysed a set of 12 nuclear markers to investigate the pattern of hybridization involving three species of sea turtles: hawksbill (E. imbricata), loggerhead (Caretta caretta) and olive ridley (Lepidochelys olivacea). Our data indicate that most of the individuals in the crossings L. olivacea × E. imbricata and L. olivacea × C. caretta are F1 hybrids, whereas C. caretta × E. imbricata crossings present F1 and backcrosses with both parental species. In addition, the C. caretta × E. imbricata hybridization seems to be gender and species biased, and we also found one individual with evidence of multispecies hybridization among C. caretta × E. imbricata × Chelonia mydas. The overall results also indicate that hybridization in this area is a recent phenomenon, spanning at least two generations or ~40 years. © 2012 Blackwell Publishing Ltd.

  10. Stationary Anonymous Sequential Games with Undiscounted Rewards.

    Science.gov (United States)

    Więcek, Piotr; Altman, Eitan

    Stationary anonymous sequential games with undiscounted rewards are a special class of games that combine features from both population games (infinitely many players) with stochastic games. We extend the theory for these games to the cases of total expected reward as well as to the expected average reward. We show that in the anonymous sequential game equilibria correspond to the limits of those of related finite population games as the number of players grows to infinity. We provide examples to illustrate our results.

  11. Genetic diversity and structure of wild populations of Carica papaya in Northern Mesoamerica inferred by nuclear microsatellites and chloroplast markers.

    Science.gov (United States)

    Chávez-Pesqueira, Mariana; Núñez-Farfán, Juan

    2016-12-01

    Few studies have evaluated the genetic structure and evolutionary history of wild varieties of important crop species. The wild papaya (Carica papaya) is a key element of early successional tropical and sub-tropical forests in Mexico, and constitutes the genetic reservoir for evolutionary potential of the species. In this study we aimed to determine how diverse and structured is the genetic variability of wild populations of C. papaya in Northern Mesoamerica. Moreover, we assessed if genetic structure and evolutionary history coincide with hypothetized (1) pre-Pleistocene events (Isthmus of Tehuantepec sinking), (2) Pleistocene refugia or (3) recent patterns. We used six nuclear and two chloroplast (cp) DNA markers to assess the genetic diversity and phylogeographical structure of 19 wild populations of C. papaya in its natural distribution in Northern Mesoamerica. We found high genetic diversity (H o = 0·681 for nuclear markers, and h = 0·701 for cpDNA markers) and gene flow between populations of C. papaya (migration r up to 420 km). A lack of phylogeographical structure was found with the cpDNA markers (NST Mesoamerica did not experience important climate fluctuations during the Pleistocene, and that the life history of C. papaya could have promoted long-distance dispersal and rapid colonization of lowland rainforests. Moreover, the results obtained with the nuclear markers suggest recent human disturbances. The fragmentation of tropical habitats in Northern Mesoamerica appears to be the main driver of genetic structuring, and the major threat to the dispersion and survival of the species in the wild. © The Author 2016. Published by Oxford University Press on behalf of the Annals of Botany Company. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  12. Development of novel low-copy nuclear markers for Hieraciinae (Asteraceae) and their perspective for other tribes

    Czech Academy of Sciences Publication Activity Database

    Krak, Karol; Álvarez, I.; Caklová, Petra; Costa, A.; Chrtek, Jindřich; Fehrer, Judith

    2012-01-01

    Roč. 99, č. 2 (2012), s. 74-77 ISSN 0002-9122 R&D Projects: GA ČR GAP506/10/1363; GA ČR GA206/05/0657 Institutional research plan: CEZ:AV0Z60050516 Keywords : Asteraceae * Hieraciinae * low-copy nuclear markers Subject RIV: EF - Botanics Impact factor: 2.586, year: 2012

  13. Developing nuclear DNA phylogenetic markers in the angiosperm genus Leucadendron (Proteaceae): a next-generation sequencing transcriptomic approach.

    Science.gov (United States)

    Tonnabel, Jeanne; Olivieri, Isabelle; Mignot, Agnès; Rebelo, Anthony; Justy, Fabienne; Santoni, Sylvain; Caroli, Stéfanie; Sauné, Laure; Bouchez, Olivier; Douzery, Emmanuel J P

    2014-01-01

    Despite the recent advances in generating molecular data, reconstructing species-level phylogenies for non-models groups remains a challenge. The use of a number of independent genes is required to resolve phylogenetic relationships, especially for groups displaying low polymorphism. In such cases, low-copy nuclear exons and non-coding regions, such as 3' untranslated regions (3'-UTRs) or introns, constitute a potentially interesting source of nuclear DNA variation. Here, we present a methodology meant to identify new nuclear orthologous markers using both public-nucleotide databases and transcriptomic data generated for the group of interest by using next generation sequencing technology. To identify PCR primers for a non-model group, the genus Leucadendron (Proteaceae), we adopted a framework aimed at minimizing the probability of paralogy and maximizing polymorphism. We anchored when possible the right-hand primer into the 3'-UTR and the left-hand primer into the coding region. Seven new nuclear markers emerged from this search strategy, three of those included 3'-UTRs. We further compared the phylogenetic potential between our new markers and the ribosomal internal transcribed spacer region (ITS). The sequenced 3'-UTRs yielded higher polymorphism rates than the ITS region did. We did not find strong incongruences with the phylogenetic signal contained in the ITS region and the seven new designed markers but they strongly improved the phylogeny of the genus Leucadendron. Overall, this methodology is efficient in isolating orthologous loci and is valid for any non-model group given the availability of transcriptomic data. Copyright © 2013 Elsevier Inc. All rights reserved.

  14. Origins of the amphiploid species Brassica napus L. investigated by chloroplast and nuclear molecular markers

    Directory of Open Access Journals (Sweden)

    Allender Charlotte J

    2010-03-01

    Full Text Available Abstract Background The amphiploid species Brassica napus (oilseed rape, Canola is a globally important oil crop yielding food, biofuels and industrial compounds such as lubricants and surfactants. Identification of the likely ancestors of each of the two genomes (designated A and C found in B. napus would facilitate incorporation of novel alleles from the wider Brassica genepool in oilseed rape crop genetic improvement programmes. Knowledge of the closest extant relatives of the genotypes involved in the initial formation of B. napus would also allow further investigation of the genetic factors required for the formation of a stable amphiploid and permit the more efficient creation of fully fertile re-synthesised B. napus. We have used a combination of chloroplast and nuclear genetic markers to investigate the closest extant relatives of the original maternal progenitors of B. napus. This was based on a comprehensive sampling of the relevant genepools, including 83 accessions of A genome B. rapa L. (both wild and cultivated types, 94 accessions of B. napus and 181 accessions of C genome wild and cultivated B. oleracea L. and related species. Results Three chloroplast haplotypes occurred in B. napus. The most prevalent haplotype (found in 79% of accessions was not present within the C genome accessions but was found at low frequencies in B. rapa. Chloroplast haplotypes characteristic of B. napus were found in a small number of wild and weedy B. rapa populations, and also in two accessions of cultivated B. rapa 'brocoletto'. Whilst introgression of the B. napus chloroplast type in the wild and weedy B. rapa populations has been proposed by other studies, the presence of this haplotype within the two brocoletto accessions is unexplained. Conclusions The distribution of chloroplast haplotypes eliminate any of the C genome species as being the maternal ancestor of the majority of the B. napus accessions. The presence of multiple chloroplast

  15. Anon-Pass: Practical Anonymous Subscriptions

    Science.gov (United States)

    Lee, Michael Z.; Dunn, Alan M.; Katz, Jonathan; Waters, Brent; Witchel, Emmett

    2014-01-01

    We present the design, security proof, and implementation of an anonymous subscription service. Users register for the service by providing some form of identity, which might or might not be linked to a real-world identity such as a credit card, a web login, or a public key. A user logs on to the system by presenting a credential derived from information received at registration. Each credential allows only a single login in any authentication window, or epoch. Logins are anonymous in the sense that the service cannot distinguish which user is logging in any better than random guessing. This implies unlinkability of a user across different logins. We find that a central tension in an anonymous subscription service is the service provider’s desire for a long epoch (to reduce server-side computation) versus users’ desire for a short epoch (so they can repeatedly “re-anonymize” their sessions). We balance this tension by having short epochs, but adding an efficient operation for clients who do not need unlinkability to cheaply re-authenticate themselves for the next time period. We measure performance of a research prototype of our protocol that allows an independent service to offer anonymous access to existing services. We implement a music service, an Android-based subway-pass application, and a web proxy, and show that adding anonymity adds minimal client latency and only requires 33 KB of server memory per active user. PMID:24504081

  16. Performance evaluation of various K- anonymity techniques

    Science.gov (United States)

    Maheshwarkar, Nidhi; Pathak, Kshitij; Chourey, Vivekanand

    2011-12-01

    Today's advanced scenario where each information is available in one click, data security is the main aspect. Individual information which sometimes needs to be hiding is easily available using some tricks. Medical information, income details are needed to be kept away from adversaries and so, are stored in private tables. Some publicly released information contains zip code, sex, birth date. When this released information is linked with the private table, adversary can detect the whole confidential information of individuals or respondents, i.e. name, medical status. So to protect respondents identity, a new concept k-anonymity is used which means each released record has at least (k-1) other records in the release whose values are distinct over those fields that appear in the external data. K-anonymity can be achieved easily in case of single sensitive attributes i.e. name, salary, medical status, but it is quiet difficult when multiple sensitive attributes are present. Generalization and Suppression are used to achieve k-anonymity. This paper provides a formal introduction of k-anonymity and some techniques used with it l-diversity, t-closeness. This paper covers k-anonymity model and the comparative study of these concepts along with a new proposed concept for multiple sensitive attributes.

  17. Decision no 2010-DC-0188 by the Nuclear Safety Authority on the 7. of July 2010 specifying to Electricite de France-Societe Anonyme (EDF-SA) the limits of releases in the environment of liquid and gaseous effluents for the operation of Flamanville 1 (IBN n 108), Flamanville 2 (INB n 109) and Flamanville 3 (INB n 167) reactors

    International Nuclear Information System (INIS)

    2010-01-01

    This document contains references to the different legal and official documents (codes, orders, minister's opinion, public surveys, administrative authorizations, local community opinion) at the root of this specification of limits related to releases in the environment of liquid and gaseous effluents by the three Flamanville nuclear reactors operated by Electricite de France-Societe Anonyme (EDF-SA). Tables present the limits for different gaseous and liquid radioactive emissions (carbon 14, hydrogen 3, iodine, radioactive rare earths, and other beta and gamma emitters) from these different installations, but also the maximum admitted concentrations for gaseous chemical effluents (boric acid, hydrazine hydrate, morpholine, phosphates, nitrates, various metals, and so on). The limits for thermal releases are also specified

  18. Characterization of nuclear and chloroplast microsatellite markers for Falcaria vulgaris (Apiaceae)

    Science.gov (United States)

    Sarbottam Piya; Madhav P. Nepal

    2013-01-01

    Falcaria vulgaris (sickleweed) is native to Eurasia and a potential invasive plant of the United States. No molecular markers have been developed so far for sickleweed. Characterization of molecular markers for this plant would allow investigation into its population structure and biogeography thereby yielding insights into risk analysis and effective management...

  19. Is it OK to be an Anonymous?

    Directory of Open Access Journals (Sweden)

    Philip Serracino-Inglott

    2013-12-01

    Full Text Available Do the deviant acts carried out by the collective known as Anonymous qualify as vigilante activity, and if so, can they be justified? Addressing this question helps expose the difficulties of morally evaluating technologically enabled deviance. Anonymous is a complex, fluid actor but not as mysterious as popularly portrayed. Under a definition of vigilantism that includes reprobative punishment rather than violence as a key element, Anonymous are vigilantes. Many of its Ops can be justified in view of the mismatch between formal norm enforcement practice and Internet natives’ experience of it. Anons are more like eco-warriors than terrorists. While their actions are contentious, their force is framed in a vision of common good that is not unreasonable. Engaging with online deviants is shown to be a productive way of identifying the weaknesses in concepts underpinning moral evaluation of Internet-enabled phenomena.

  20. Scalable and Anonymous Group Communication with MTor

    Directory of Open Access Journals (Sweden)

    Lin Dong

    2016-04-01

    Full Text Available This paper presents MTor, a low-latency anonymous group communication system. We construct MTor as an extension to Tor, allowing the construction of multi-source multicast trees on top of the existing Tor infrastructure. MTor does not depend on an external service to broker the group communication, and avoids central points of failure and trust. MTor’s substantial bandwidth savings and graceful scalability enable new classes of anonymous applications that are currently too bandwidth-intensive to be viable through traditional unicast Tor communication-e.g., group file transfer, collaborative editing, streaming video, and real-time audio conferencing.

  1. Anonymous communication networks protecting privacy on the web

    CERN Document Server

    Peng, Kun

    2014-01-01

    In today's interactive network environment, where various types of organizations are eager to monitor and track Internet use, anonymity is one of the most powerful resources available to counterbalance the threat of unknown spectators and to ensure Internet privacy.Addressing the demand for authoritative information on anonymous Internet usage, Anonymous Communication Networks: Protecting Privacy on the Web examines anonymous communication networks as a solution to Internet privacy concerns. It explains how anonymous communication networks make it possible for participants to communicate with

  2. An outcome study of Gamblers Anonymous.

    Science.gov (United States)

    Stewart, R M; Brown, R I

    1988-02-01

    Retrospective and prospective studies of a total sample of 232 attenders at groups of Gamblers Anonymous suggest that total abstinence from gambling was maintained by 8% of all comers at one year from first attendance and by 7% at two years.

  3. Anticipating anonymity in screening program databases.

    Science.gov (United States)

    Caballero, Rafael; Sen, Sagar; Nygård, Jan F

    2017-07-01

    In this paper, we propose a technique for improving anonymity in screening program databases to increase the privacy for the participants in these programs. The data generated by the invitation process (screening centre, appointment date) is often made available to researchers for medical research and for evaluation and improvement of the screening program. This information, combined with other personal quasi-identifiers such as the ZIP code, gender or age, can pose a risk of disclosing the identity of the individuals participating in the program, and eventually their test results. We present two algorithms that produce a set of screening appointments that aim to increase anonymity of the resulting dataset. The first one, based on the constraint programming paradigm, defines the optimal appointments, while the second one is a suboptimal heuristic algorithm that can be used with real size datasets. The level of anonymity is measured using the new concept of generalized k-anonymity, which allows us to show the utility of the proposal by means of experiments, both using random data and data based on screening invitations from the Norwegian Cancer Registry. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Anonymous publication of sensitive transactional data

    KAUST Repository

    Ghinita, Gabriel

    2011-02-01

    Existing research on privacy-preserving data publishing focuses on relational data: in this context, the objective is to enforce privacy-preserving paradigms, such as k-anonymity and ℓ-diversity, while minimizing the information loss incurred in the anonymizing process (i.e., maximize data utility). Existing techniques work well for fixed-schema data, with low dimensionality. Nevertheless, certain applications require privacy-preserving publishing of transactional data (or basket data), which involve hundreds or even thousands of dimensions, rendering existing methods unusable. We propose two categories of novel anonymization methods for sparse high-dimensional data. The first category is based on approximate nearest-neighbor (NN) search in high-dimensional spaces, which is efficiently performed through locality-sensitive hashing (LSH). In the second category, we propose two data transformations that capture the correlation in the underlying data: 1) reduction to a band matrix and 2) Gray encoding-based sorting. These representations facilitate the formation of anonymized groups with low information loss, through an efficient linear-time heuristic. We show experimentally, using real-life data sets, that all our methods clearly outperform existing state of the art. Among the proposed techniques, NN-search yields superior data utility compared to the band matrix transformation, but incurs higher computational overhead. The data transformation based on Gray code sorting performs best in terms of both data utility and execution time. © 2006 IEEE.

  5. Evaluation of Urinary Nuclear Matrix Protein-22 as Tumor Marker Versus Tissue Polypeptide Specific Antigen in Bilharzial and Bladder Cancer

    International Nuclear Information System (INIS)

    Ahmed, W.A.; El-Kabany, H.

    2004-01-01

    Urinary nuclear matrix protein-22 (NMP-22) and tissue polypeptide specific antigen (TPS) were determined as potential marker for early detection of bladder tumors in patients with high risk (Bilharzial-patients), monitoring and follow up bladder cancer patients. The objective was to determine sensitivity and specificity of markers for bilharzial and cancer lesions. The levels of two parameters were determined pre and post operation. A total of 110 individuals, 20 healthy, 20 bilharzial patients and 70 bladder cancer patients with confirmed diagnosis were investigated. Urine samples were assayed for NMP-22 and TPS test kits. Some bladder cancer patients were selected to follow up. NMP-22 showed highly significant increase (P,0.001) more than TPS (P<0.01) in bladder cancer patients when compared with bilharzial and control group. Overall sensitivity is 7.8% for TPS and 98.5% for NMP-22

  6. Analysis of the Genetic Diversity and Population Structure of Latvian Ash (Fraxinus excelsior L. Stands using Nuclear and Chloroplast SSR Markers

    Directory of Open Access Journals (Sweden)

    Ruņģis Dainis

    2016-06-01

    Full Text Available Common ash (Fraxinus excelsior L. has a widespread distribution throughout Europe, and Latvia is almost at the north eastern edge of the distribution range. In Europe, ash is threatened by ash dieback, a disease caused by the introduced ascomycete Hymenoscyphus fraxineus. Chloroplast and nuclear DNA markers have been used to study the genetic diversity and population structure of ash both in a broader pan-European context as well as in more restricted regions. Some of the markers analysed in these previously published reports were also utilised in this study, enabling comparisons of the genetic parameters calculated from the nuclear SSR marker data and of the haplotypes identified with the chloroplast markers. Analysis of chloroplast markers revealed one dominant haplotype in Latvian stands, which corresponds to the haplotype previously found in Eastern Europe and Scandinavia. A second haplotype, corresponding to a previously reported central European haplotype was found in all individuals from the Ķemeri stand, indicating that this stand was naturally established from introduced germplasm, which was planted in a neighbouring park. The nuclear SSR markers revealed low levels of differentiation of Latvian F. excelsior stands, probably due efficient pollen flow between stands. The analysis of both chloroplast and nuclear DNA markers has revealed different aspects of the structure and provenance of Latvian F. excelsior populations.

  7. EpCAM nuclear localization identifies aggressive Thyroid Cancer and is a marker for poor prognosis

    Directory of Open Access Journals (Sweden)

    MacMillan Christina

    2010-06-01

    Full Text Available Abstract Background Proteolytic cleavage of the extracellular domain (EpEx of Epithelial cell adhesion molecule (EpCAM and nuclear signaling by its intracellular oncogenic domain Ep-ICD has recently been implicated in increased proliferation of cancer cells. The clinical significance of Ep-ICD in human tumors remains an enigma. Methods EpEx, Ep-ICD and β-catenin immunohistochemistry using specific antibodies was conducted on 58 archived thyroid cancer (TC tissue blocks from 34 patients and correlated with survival analysis of these patients for up to 17 years. Results The anaplastic (ATC and aggressive thyroid cancers showed loss of EpEx and increased nuclear and cytoplasmic accumulation of Ep-ICD. In contrast, the low grade papillary thyroid cancers (PTC showed membranous EpEx and no detectable nuclear Ep-ICD. The ATC also showed concomitant nuclear expression of Ep-ICD and β-catenin. Kaplan-Meier Survival analysis revealed reduced overall survival (OS for TC patients showing nuclear Ep-ICD expression or loss of membranous EpEx (p Conclusion We report reciprocal loss of membrane EpEx but increased nuclear and cytoplasmic accumulation of Ep-ICD in aggressive TC; nuclear Ep-ICD correlated with poor OS of TC patients. Thus nuclear Ep-ICD localization may serve as a useful biomarker for aggressive TC and may represent a novel diagnostic, prognostic and therapeutic target for aggressive TC.

  8. Order of the 17. of June 2010 approving the decision no 2010-DC-0182 by the Nuclear Safety Authority on the 18. of May 2010 specifying the limits of releases in the environment of liquid and gaseous effluents of civil base nuclear installations no 46, 74 and 100 operated by Electricite de France-Societe Anonyme (EDF-SA) on the district of Saint-Laurent-Nouan (Loir-et-Cher department)

    International Nuclear Information System (INIS)

    2010-01-01

    This legal publication contains references to the different legal and official documents (codes, orders, minister's opinion, public surveys, administrative authorizations, local community opinion) at the root of this specification of limits related to releases in the environment of liquid and gaseous effluents of civil base nuclear installations operated by Electricite de France-Societe Anonyme (EDF-SA) on the district of Saint-Laurent-Nouan. Tables present the limits for different radioactive emissions (carbon 14, hydrogen 3, iodine, radioactive rare earths, and other alpha, beta and gamma emitters) from these different installations, but also the maximum admitted concentrations for gaseous chemical effluents (boric acid, hydrazine, morpholine, phosphates, nitrates, various metals, and so on). The limits for thermal releases are also specified

  9. Decision no 2010-DC-0182 by the Nuclear Safety Authority on the 18. of May 2010 specifying the limits of releases in the environment of liquid and gaseous effluents of civil base nuclear installations no 46, no 74 and no 100 operated by Electricite de France-Societe Anonyme (EDF-SA) on the district of Saint-Laurent-Nouan (Loir-et-Cher department)

    International Nuclear Information System (INIS)

    2010-01-01

    This document contains references to the different legal and official documents (codes, orders, minister's opinion, public surveys, administrative authorizations, local community opinion) at the root of this specification of limits related to releases in the environment of liquid and gaseous effluents of civil base nuclear installations operated by Electricite de France-Societe Anonyme (EDF-SA) on the district of Saint-Laurent-Nouan. Commented tables in appendix present the limits for different radioactive emissions (carbon 14, hydrogen 3, iodine, radioactive rare earths, and other alpha, beta and gamma emitters) from these different installations, but also the maximum admitted concentrations for gaseous chemical effluents (boric acid, hydrazine, morpholine, phosphates, nitrates, various metals, and so on). The limits for thermal releases are also specified

  10. EpCAM nuclear localization identifies aggressive Thyroid Cancer and is a marker for poor prognosis

    International Nuclear Information System (INIS)

    Ralhan, Ranju; Cao, Jun; Lim, Terence; MacMillan, Christina; Freeman, Jeremy L; Walfish, Paul G

    2010-01-01

    Proteolytic cleavage of the extracellular domain (EpEx) of Epithelial cell adhesion molecule (EpCAM) and nuclear signaling by its intracellular oncogenic domain Ep-ICD has recently been implicated in increased proliferation of cancer cells. The clinical significance of Ep-ICD in human tumors remains an enigma. EpEx, Ep-ICD and β-catenin immunohistochemistry using specific antibodies was conducted on 58 archived thyroid cancer (TC) tissue blocks from 34 patients and correlated with survival analysis of these patients for up to 17 years. The anaplastic (ATC) and aggressive thyroid cancers showed loss of EpEx and increased nuclear and cytoplasmic accumulation of Ep-ICD. In contrast, the low grade papillary thyroid cancers (PTC) showed membranous EpEx and no detectable nuclear Ep-ICD. The ATC also showed concomitant nuclear expression of Ep-ICD and β-catenin. Kaplan-Meier Survival analysis revealed reduced overall survival (OS) for TC patients showing nuclear Ep-ICD expression or loss of membranous EpEx (p < 0.0004), median OS = 5 months as compared to 198 months for patients who did not show nuclear Ep-ICD or demonstrated only membranous EpE. We report reciprocal loss of membrane EpEx but increased nuclear and cytoplasmic accumulation of Ep-ICD in aggressive TC; nuclear Ep-ICD correlated with poor OS of TC patients. Thus nuclear Ep-ICD localization may serve as a useful biomarker for aggressive TC and may represent a novel diagnostic, prognostic and therapeutic target for aggressive TC

  11. Mitochondrial and nuclear markers highlight the biodiversity of Kalotermes flavicollis (Fabricius, 1793) (Insecta, Isoptera, Kalotermitidae) in the Mediterranean area.

    Science.gov (United States)

    Velonà, A; Luchetti, A; Ghesini, S; Marini, M; Mantovani, B

    2011-06-01

    The biodiversity of the European termite Kalotermes flavicollis is here studied through the analysis of mitochondrial (303 bp of control region and 912 bp of COI/tRNA(Leu)/COII) and nuclear (five microsatellite and 20 Inter-SINE loci) markers on 18 colonies collected in Southern France, Corsica, Sardinia, peninsular Italy, the Balkans and Greece. Different statistical analyses (Bayesian phylogenetic analysis,parsimony network, F-statistics, PCA) were performed. Mitochondrial sequences produced an unresolved polytomy including samples from peninsular Italy, Balkans and Greece, and three main clades: southern France, Corsica-Sardinia and Portoscuso(SW Sardinia). Nuclear markers confirm these data, further highlighting a more significant divergence at the regional scale. The results obtained for the peri-Tyrrhenian area agree with major paleogeographic and paleoclimatic events that shaped the biodiversity of the local fauna. K. flavicollis biodiversity and its phylogeographic pattern are also evaluated in the light of the data available for the other native European termite taxon (genus Reticulitermes), in order to produce a more complete scenario of the Mediterranean. In the area comprised between southern France and Italy, the degree of diversity is similar; however, in the eastern area, while K. flavicollis is differentiated only at the population level, the genus Reticulitermes comprises at least six entities of specific and/or subspecific level. This discrepancy may be explained by taking into account the different evolutionary histories of the two taxa.

  12. Anonymity-Preserving Public-Key Encryption

    DEFF Research Database (Denmark)

    Kohlweiss, Markulf; Maurer, Ueli; Onete, Cristina

    2013-01-01

    A receiver-anonymous channel allows a sender to send a message to a receiver without an adversary learning for whom the message is intended. Wireless broadcast channels naturally provide receiver anonymity, as does multi-casting one message to a receiver population containing the intended receiver...... by applying a cryptographic scheme explicit in the constructed (ideal) resource; this specifies the exact requirements for the applicability of a cryptographic scheme in a given context. It also allows to decide which of the existing security properties of such a cryptographic scheme are adequate...... for the considered scenario, and which are too weak or too strong. Here, we show that weak robustness is necessary but that so-called strong robustness is unnecessarily strong in that it does not construct a (natural) stronger resource....

  13. Academic freedom, public reactions, and anonymity.

    Science.gov (United States)

    Häyry, Matti

    2014-05-01

    Academic freedom can be defined as immunity against adverse reactions from the general public, designed to keep scholars unintimidated and productive even after they have published controversial ideas. Francesca Minerva claims that this notion of strict instrumental academic freedom is supported by Ronald Dworkin, and that anonymity would effectively defend the sphere of immunity implied by it. Against this, I argue that the idea defended by Minerva finds no support in the work by Dworkin referred to; that anonymity would not in most cases effectively protect the kind of immunity sought after; and that in some cases it would not even be desirable to protect scholars from public reactions to their controversial claims. © 2014 John Wiley & Sons Ltd.

  14. Nuclear ribosomal internal transcribed spacer (ITS) region as a universal DNA barcode marker for Fungi

    NARCIS (Netherlands)

    Schoch, C.L.; Seifert, K.A.; Huhndorf, S.; Robert, V.; Spouge, J.L.; Levesque, C.A.; Chen, W.; Fungal Barcoding Consortium, [No Value

    2012-01-01

    Six DNA regions were evaluated as potential DNA barcodes for Fungi, the second largest kingdom of eukaryotic life, by a multinational, multilaboratory consortium. The region of the mitochondrial cytochrome c oxidase subunit 1 used as the animal barcode was excluded as a potential marker, because it

  15. Anonymous electronic trading versus floor trading

    OpenAIRE

    Franke, Günter; Hess, Dieter

    1995-01-01

    This paper compares the attractiveness of floor trading and anonymous electronic trading systems. It is argued that in times of low information intensity the insight into the order book of the electronic trading system provides more valuable information than floor trading, but in times of high information intensity the reverse is true. Thus, the electronic system's market share in trading activity should decline in times of high information intensity. This hypothesis is tested by data on BUND...

  16. Nuclear markers, mitochondrial DNA and male secondary sexual traits variation in a newt hybrid zone (Triturus vulgaris x T. montandoni).

    Science.gov (United States)

    Babik, W; Szymura, J M; Rafiński, J

    2003-07-01

    The smooth and the Montandon's newts (Triturus vulgaris and T. montandoni) are genetically similar sister species with highly divergent male secondary sexual traits involved in complex courtship behaviour. Their parapatric ranges overlap at moderate elevations in the Carpathian Mountains where they hybridize readily. Here we present a detailed study of genetic and morphological variation in populations from the area of sympatry. Analysis of variation at seven nuclear markers, mtDNA and male sexual secondary traits was complemented with an ecological survey of breeding sites characteristics. Extensive hybridization was revealed with back-cross individuals similar to either parental species predominating among hybrids. The hybrid zone exhibited a mosaic pattern: the genetic composition of the populations was correlated only weakly with their geographical position. No association with habitat type was found. Departures from Hardy-Weinberg proportions, significant linkage disequilibria and bimodal distribution of genotypes suggest strongly that assortative mating is an important factor shaping the genetic composition of hybrid populations. The pattern of cytonuclear disequilibria did not indicate much asymmetry in interspecific matings. Changes in the frequency of nuclear markers were highly concordant, whereas mtDNA showed much wider bidirectional introgression with 14% excess of T. montandoni haplotype. We argue that the mosaic structure of the newt hybrid zone results mainly from stochastic processes related to extinction and recolonization. Microgeographical differences in mtDNA introgression are explained by historical range shifts. Since morphologically intermediate males were underrepresented when compared to hybrid males identified by genetic markers, sexual selection acting against the morphological intermediates is implied. We discuss the implications of these findings in the context of reinforcement of prezygotic isolation in newts.

  17. Anonymous quantum communications using the quantum one-time pad

    International Nuclear Information System (INIS)

    Wang, Qing-Le; Gao, Fei-; Liu, Bin; Song, Ting-Ting; Wen, Qiao-Yan

    2015-01-01

    We present the first quantum secure communication protocol for an anonymous receiver without the assistance of anonymous entanglement. In previous works, if a public sender wants to send quantum messages to a chosen receiver while protecting the identity of the receiver from others, all participants should cooperate first to construct the entanglement between the sender and the anonymous receiver. This is the most important process in anonymous quantum communications. With anonymous entanglement, the sender can communicate quantum messages to the anonymous receiver by applying teleportation protocols. In contrast, our protocol is novel and achieves communication of quantum messages directly from the public sender to the anonymous receiver based on the quantum one-time pad and current achievements. Notably, the anonymity of the receiver, as well as the privacy of the quantum messages, is perfectly protected with the exception of an exponentially small probability in our protocol. (paper)

  18. Protecting whistle-blowers: Anonymity on the internet

    International Nuclear Information System (INIS)

    Guinnessy, P.

    1997-01-01

    Even though strict legislation exists in many countries, it appears that the next few years should be a golden opportunity for groups to successfully monitor and publish the activity of the nuclear states, and human right violations through use of the Internet. The reasons for this are: 1. The Internet is becoming widespread even in repressive regimes; 2. Software is available to either hide messages from others or hide the mailers account; 3. Information from sites in other countries can be easily obtained to be read inside repressive regimes from the Internet. In this regard It is suggested the Pugwash or a similar organization should set up either an anonymous account to receive information or maybe use a more heavily protected cyperpunk remailer. Such an ability would hopefully prompt more people to notify treaty violations

  19. Study on Privacy Protection Algorithm Based on K-Anonymity

    Science.gov (United States)

    FeiFei, Zhao; LiFeng, Dong; Kun, Wang; Yang, Li

    Basing on the study of K-Anonymity algorithm in privacy protection issue, this paper proposed a "Degree Priority" method of visiting Lattice nodes on the generalization tree to improve the performance of K-Anonymity algorithm. This paper also proposed a "Two Times K-anonymity" methods to reduce the information loss in the process of K-Anonymity. Finally, we used experimental results to demonstrate the effectiveness of these methods.

  20. Assessing Anonymous Communication on the Internet: Policy Deliberations.

    Science.gov (United States)

    Kling, Rob; Lee, Yaching; Frankel, Mark S.; Teich, Al

    1999-01-01

    Examines the social character of anonymous online communication and the ways that anonymous communication has played important roles for professionals such as journalists and the police. Explains some of the new technological supports for anonymous communication on the Internet. Discusses some of the nuances behind the controversies and policy…

  1. Anonymity: An Impediment to Performance in Healthcare

    Directory of Open Access Journals (Sweden)

    Daniel W. Karlsberg

    2014-01-01

    Full Text Available Many teaching hospitals employ a care team structure composed of a broad range of healthcare providers with different skill sets. Each member of this team has a distinct role and a different level of training ranging from attending physician to resident, intern, and medical student. Often times, these different roles lead to greater complexity and confusion for both patients and nursing staff. It has been demonstrated that patients have a great degree of difficulty in identifying members of their care team. This anonymity also exists between nursing staff and other care providers. In order to better understand the magnitude of anonymity within the teaching hospital, a ten-question survey was sent to nurses across three different departments. Results from this survey demonstrated that 71% of nurses are “Always” or “Often” able to identify which care team is responsible for their patients, while 79% of nurses reported that they either “Often” or “Sometimes” page a provider who is not currently caring for a given patient. Furthermore, 33% of nurses felt that they were either “Rarely” or “Never” able to recognize, by face and name, attending level providers. Residents were “Rarely” or “Never” recognized by face and name 37% of the time, and interns 42% of the time. Contacting the wrong provider repeatedly leads to de facto delays in medication, therapy, and diagnosis. Additionally, these unnecessary interruptions slow workflow for both nurses and members of the care team, making hospital care less efficient and safe overall. Technological systems should focus on reducing anonymity within the hospital in order to enhance healthcare delivery.

  2. An Extensive Study on Data Anonymization Algorithms Based on K-Anonymity

    Science.gov (United States)

    Simi, Ms. M. S.; Sankara Nayaki, Mrs. K.; Sudheep Elayidom, M., Dr.

    2017-08-01

    For business and research oriented works engaging Data Analysis and Cloud services needing qualitative data, many organizations release huge microdata. It excludes an individual’s explicit identity marks like name, address and comprises of specific information like DOB, Pin-code, sex, marital status, which can be combined with other public data to recognize a person. This implication attack can be manipulated to acquire any sensitive information from social network platform, thereby putting the privacy of a person in grave danger. To prevent such attacks by modifying microdata, K-anonymization is used. With potentially increasing data, the effective method to anonymize it stands challenging. After series of trails and systematic comparison, in this paper, we propose three best algorithms along with its efficiency and effectiveness. Studies help researchers to identify the relationship between the values of k, degree of anonymization, choosing a quasi-identifier and focus on execution time.

  3. Plasma Nuclear and Mitochondrial DNA Levels, and Markers of Inflammation, Shock, and Organ Damage in Patients with Septic Shock.

    Science.gov (United States)

    Timmermans, Kim; Kox, Matthijs; Scheffer, Gert Jan; Pickkers, Peter

    2016-06-01

    Plasma levels of the danger-associated molecular patterns (DAMPs) nuclear DNA (nDNA) and mitochondrial DNA (mtDNA) have been shown to be related to sepsis mortality. However, the intermediate factors and/or mechanisms contributing to this relation are largely unknown. Our aim was to determine whether plasma levels of nDNA and mtDNA are related to the markers of inflammation, severity of shock, and organ damage in septic shock patients. Moreover, we investigated the relationship between plasma levels of nDNA/mtDNA and inflammatory cytokines during experimental human endotoxemia, a model of systemic inflammation in humans in vivo mimicking some of the hallmarks of early sepsis. Blood was sampled from the onset of septic shock until day 28 in 121 septic shock patients and from 1 h before endotoxin administration until 8 h afterward in 12 healthy volunteers. Plasma concentrations of five cytokines and circulating levels of nDNA and mtDNA were measured, and correlations with shock-related parameters and markers of organ damage were investigated. In septic shock patients plasma cytokine concentrations, as well as nDNA and mtDNA levels, were increased at the onset of septic shock and remained elevated. During the first 5 days of septic shock, nDNA levels consistently correlated with plasma cytokine concentrations as well as with the shock-related parameter norepinephrine infusion rate and markers of organ damage (total bilirubin and creatinine). Experimental human endotoxemia also resulted in increased levels of plasma nDNA and mtDNA, but to a lesser extent than in septic shock patients. Furthermore, nDNA levels correlated with pro-inflammatory cytokines during endotoxemia. Our findings indicate a relationship between plasma nDNA levels and the inflammatory response. Furthermore, nDNA levels are associated with markers of shock and organ damage in septic shock patients. Nevertheless, the correlations found are relatively weak and it remains to be determined whether n

  4. Suicidal behavior among members of Gamblers Anonymous.

    Science.gov (United States)

    Frank, M L; Lester, D; Wexler, A

    1991-09-01

    A national sample of 500 members of Gamblers Anonymous was surveyed by mail in order to gather information on suicidal history. One hundred sixty two usable surveys were returned representing 32.4% of the original sample. Compulsive gamblers who had a history of suicidal preoccupation began gambling at an earlier age than nonsuicidal gamblers and were more likely to have stolen to support their gambling. They also tended to have addicted relatives and children more than nonsuicidal gamblers did. The data suggest that those gamblers who had been suicidal tend to be more serious gamblers than nonsuicidal respondents.

  5. First genetic characterization of Fasciola hepatica in Argentina by nuclear and mitochondrial gene markers.

    Science.gov (United States)

    Carnevale, Silvana; Malandrini, Jorge Bruno; Pantano, María Laura; Soria, Claudia Cecilia; Rodrigues-Silva, Rosângela; Machado-Silva, José Roberto; Velásquez, Jorge Néstor; Kamenetzky, Laura

    2017-10-15

    Fasciola hepatica is a trematode showing genetic variation among isolates from different regions of the world. The objective of this work was to characterize for the first time F. hepatica isolates circulating in different regions of Argentina. Twenty-two adult flukes were collected from naturally infected bovine livers in different areas from Argentina and used for DNA extraction. We carried out PCR amplification and sequence analysis of the ribosomal internal transcribed spacer 1 (ITS1), mitochondrial nicotinamide adenine dinucleotide dehydrogenase subunits 4 and 5 (nad4 and nad5) and mitochondrial cytochrome c oxidase subunit I (cox1) genes as genetic markers. Phylogenies were reconstructed using maximum parsimony algorithm. A total of 6 haplotypes were found for cox1, 4 haplotypes for nad4 and 3 haplotypes for nad5. The sequenced ITS1 fragment was identical in all samples. The analyzed cox1 gene fragment is the most variable marker and is recommended for future analyses. No geographic association was found in the Argentinean samples. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Human Homolog of Drosophila Ariadne (HHARI) is a marker of cellular proliferation associated with nuclear bodies

    Energy Technology Data Exchange (ETDEWEB)

    Elmehdawi, Fatima; Wheway, Gabrielle; Szymanska, Katarzyna [Division of Clinical Sciences, Leeds Institute of Molecular Medicine, Level 8, Wellcome Trust Brenner Building, University of Leeds, Leeds, LS9 7TF West Yorkshire (United Kingdom); Adams, Matthew [BioScreening Technology Group, Biomedical Health Research Center, Wellcome Trust Brenner Building, University of Leeds, Leeds, LS9 7TF West Yorkshire (United Kingdom); High, Alec S. [Department of Histopathology, Bexley Wing, St. James' s University Hospital, Beckett Street, Leeds, LS9 7TF West Yorkshire (United Kingdom); Johnson, Colin A., E-mail: c.johnson@leeds.ac.uk [Division of Clinical Sciences, Leeds Institute of Molecular Medicine, Level 8, Wellcome Trust Brenner Building, University of Leeds, Leeds, LS9 7TF West Yorkshire (United Kingdom); Robinson, Philip A. [Division of Clinical Sciences, Leeds Institute of Molecular Medicine, Level 8, Wellcome Trust Brenner Building, University of Leeds, Leeds, LS9 7TF West Yorkshire (United Kingdom)

    2013-02-01

    HHARI (also known as ARIH1) is an ubiquitin-protein ligase and is the cognate of the E2, UbcH7 (UBE2L3). To establish a functional role for HHARI in cellular proliferation processes, we performed a reverse genetics screen that identified n=86/522 (16.5%) ubiquitin conjugation components that have a statistically significant effect on cell proliferation, which included HHARI as a strong hit. We then produced and validated a panel of specific antibodies that establish HHARI as both a nuclear and cytoplasmic protein that is expressed in all cell types studied. HHARI was expressed at higher levels in nuclei, and co-localized with nuclear bodies including Cajal bodies (p80 coilin, NOPP140), PML and SC35 bodies. We confirmed reduced cellular proliferation after ARIH1 knockdown with individual siRNA duplexes, in addition to significantly increased levels of apoptosis, an increased proportion of cells in G2 phase of the cell cycle, and significant reductions in total cellular RNA levels. In head and neck squamous cell carcinoma biopsies, there are higher levels of HHARI expression associated with increased levels of proliferation, compared to healthy control tissues. We demonstrate that HHARI is associated with cellular proliferation, which may be mediated through its interaction with UbcH7 and modification of proteins in nuclear bodies. -- Highlights: ► We produce and validate new antibody reagents for the ubiquitin-protein ligase HHARI. ► HHARI colocalizes with nuclear bodies including Cajal, PML and SC35 bodies. ► We establish new functions in cell proliferation regulation for HHARI. ► Increased HHARI expression associates with squamous cell carcinoma and proliferation.

  7. Browsing the Internet: good-bye anonymity!

    CERN Multimedia

    Computer Security Team

    2012-01-01

    Do you consider browsing the Internet to be your private business? When visiting random web-sites, how far do you assume you are anonymous? Would it matter to you that Google or Facebook can profile your browsing behaviour in order to better target you with advertisements? Did you notice that you already get targeted ads when you are logged on to Google or Facebook even if you are visiting completely different websites? If matters to you, note that browsing anonymously on the Internet is far from easy.   When you are connected to the Internet, you give away a variety of information: your PC’s IP address, some browser settings like language or screen size, and, probably, your login information. So how private is private? You might argue that your current IP address has been picked from a pool of addresses and therefore regularly changes, so it does not necessarily always pinpoint you. On the other hand, with the dawn of IPv6 there is no need any more for shared IP addresses as the...

  8. SOX9 Is an Astrocyte-Specific Nuclear Marker in the Adult Brain Outside the Neurogenic Regions.

    Science.gov (United States)

    Sun, Wei; Cornwell, Adam; Li, Jiashu; Peng, Sisi; Osorio, M Joana; Aalling, Nadia; Wang, Su; Benraiss, Abdellatif; Lou, Nanhong; Goldman, Steven A; Nedergaard, Maiken

    2017-04-26

    Astrocytes have in recent years become the focus of intense experimental interest, yet markers for their definitive identification remain both scarce and imperfect. Astrocytes may be recognized as such by their expression of glial fibrillary acidic protein, glutamine synthetase, glutamate transporter 1 (GLT1), aquaporin-4, aldehyde dehydrogenase 1 family member L1, and other proteins. However, these proteins may all be regulated both developmentally and functionally, restricting their utility. To identify a nuclear marker pathognomonic of astrocytic phenotype, we assessed differential RNA expression by FACS-purified adult astrocytes and, on that basis, evaluated the expression of the transcription factor SOX9 in both mouse and human brain. We found that SOX9 is almost exclusively expressed by astrocytes in the adult brain except for ependymal cells and in the neurogenic regions, where SOX9 is also expressed by neural progenitor cells. Transcriptome comparisons of SOX9+ cells with GLT1+ cells showed that the two populations of cells exhibit largely overlapping gene expression. Expression of SOX9 did not decrease during aging and was instead upregulated by reactive astrocytes in a number of settings, including a murine model of amyotrophic lateral sclerosis (SOD1G93A), middle cerebral artery occlusion, and multiple mini-strokes. We quantified the relative number of astrocytes using the isotropic fractionator technique in combination with SOX9 immunolabeling. The analysis showed that SOX9+ astrocytes constitute ∼10-20% of the total cell number in most CNS regions, a smaller fraction of total cell number than previously estimated in the normal adult brain. SIGNIFICANCE STATEMENT Astrocytes are traditionally identified immunohistochemically by antibodies that target cell-specific antigens in the cytosol or plasma membrane. We show here that SOX9 is an astrocyte-specific nuclear marker in all major areas of the CNS outside of the neurogenic regions. Based on SOX9

  9. Our Anonymous Online Research Participants Are Not Always Anonymous: Is This a Problem?

    Science.gov (United States)

    Dawson, Phillip

    2014-01-01

    When educational research is conducted online, we sometimes promise our participants that they will be anonymous--but do we deliver on this promise? We have been warned since 1996 to be careful when using direct quotes in Internet research, as full-text web search engines make it easy to find chunks of text online. This paper details an empirical…

  10. Evolutionary history of Ichthyosaura alpestris (Caudata, Salamandridae) inferred from the combined analysis of nuclear and mitochondrial markers.

    Science.gov (United States)

    Recuero, Ernesto; Buckley, David; García-París, Mario; Arntzen, Jan W; Cogălniceanu, Dan; Martínez-Solano, Iñigo

    2014-12-01

    Widespread species with morphologically and ecologically differentiated populations are key to understand speciation because they allow investigating the different stages of the continuous process of population divergence. The alpine newt, Ichthyosaura alpestris, with a range that covers a large part of Central Europe as well as isolated regions in all three European Mediterranean peninsulas, and with strong ecological and life-history differences among populations, is an excellent system for such studies. We sampled individuals across most of the range of the species, and analyzed mitochondrial (1442 bp) and nuclear (two nuclear genes -1554 bp- and 35 allozyme loci) markers to produce a time-calibrated phylogeny and reconstruct the historical biogeography of the species. Phylogenetic analyses of mtDNA data produced a fully resolved topology, with an endemic, Balkan clade (Vlasina) which is sister to a clade comprising an eastern and a western group. Within the former, one clade (subspecies I. a. veluchiensis) is sister to a clade containing subspecies I. a. montenegrina and I. a. serdara as well as samples from southern Romania, Bosnia-Herzegovina, Serbia and Bulgaria (subspecies I. a. reiseri and part of I. a. alpestris). Within the western group, populations from the Italian peninsula (subspecies I. a. apuana and I. a. inexpectata) are sister to a clade containing samples from the Iberian Peninsula (subspecies I. a. cyreni) and the remainder of the samples from subspecies I. a. alpestris (populations from Hungary, Austria, Poland, France, Germany and the larger part of Romania). Results of (∗)BEAST analyses on a combined mtDNA and nDNA dataset consistently recovered with high statistical support four lineages with unresolved inter-relationships: (1) subspecies I. a. veluchiensis; (2) subspecies I. a. apuana+I. a. inexpectata; (3) subspecies I. a. cyreni+part of subspecies I. a. alpestris (the westernmost populations, plus most Romanian populations); and (4

  11. Nuclear microsatellite markers for the date palm (Phoenix dactylifera L.): characterization and utility across the genus Phoenix and in other palm genera.

    NARCIS (Netherlands)

    Billotte, N.; Marseillac, P.; Brottier, P.; Noyer, J.L.; Jacquemoud, J.P.; Moreau, C.; Couvreur, T.L.P.; Chavallier, M.H.; Pintaud, J.C.; Risterucci, A.M.

    2004-01-01

    A (GA)n microsatellite-enriched library was constructed and 16 nuclear simple sequence repeat (SSR) loci were characterized in Phoenix dactylifera. Across-taxa amplification and genotyping tests showed the utility of most SSR markers in 11 other Phoenix species and the transferability of some of

  12. Anonymous HIV surveillance in Saughton Prison, Edinburgh.

    Science.gov (United States)

    Bird, A G; Gore, S M; Jolliffe, D W; Burns, S M

    1992-07-01

    To estimate the prevalence of HIV by anonymous saliva testing in Her Majesty's Prison, Saughton (Saughton Prison), Edinburgh, UK. To elicit linked anonymous risk factor information from which to estimate risk scores for those who had taken an HIV blood test and, among drug injectors, for those who were HIV-1-antibody-positive on saliva testing. Saughton Prison on 15 and 16 August 1991; HIV Immunology and Regional Virus Laboratories, Edinburgh, and the Medical Research Council Biostatistics Unit, Cambridge, UK. Male inmates (378 out of a total of 499) of Saughton Prison. Answers to a brief questionnaire about age, usual residence, present and past custodial sentences, drug injecting and sexual behaviour prior to and in prison, HIV testing and history of acute hepatitis. HIV-1-antibody status was established by saliva testing. Eighteen per cent of participants were injecting drug users (IDU), of whom approximately one-half (47%) had injected while inside prison. Ninety men (26%), including 40 (14%) of 278 participants who had never injected drugs and 77% of IDU participants, had taken an HIV blood test. Nine per cent of all participants and 35% of IDU participants had had an acute attack of hepatitis. Forty-one (62%) of 66 IDU had been imprisoned five or more times before their current prison sentence. After taking account of region of residence, injecting drug history and acute hepatitis, aspects of sentencing and sexual behaviour were not determinants of those who had been tested for HIV. On the study days, 18 out of 499 (3.6%) participants were known to prison medical officers to be HIV-infected. Following saliva testing, HIV prevalence was 17 out of 375 (4.5%) inmates tested. All 17 had at some time 'taken the blood test for HIV' and all had injected non-medically prescribed drugs. Edinburgh residence, age 26-30 years, have injected in prison and having first injected before 1983 all contributed to the risk score for whether an IDU was HIV-1-antibody-positive on

  13. Digital anonymity on the internet : new rules for anonymous electronic transactions? an exploration of the private law implications of digital anonymity

    NARCIS (Netherlands)

    Grijpink, J.H.A.M.; Prins, C.

    2001-01-01

    This article sets out the most important conclusions of the first stage of a study into the dimensions of digital anonymity. It is intended to set out the problem, make people aware of the intricacies of the problem and thus stimulate the debate on useful legal structures for anonymity. The

  14. The k-Anonymity Problem Is Hard

    Science.gov (United States)

    Bonizzoni, Paola; Della Vedova, Gianluca; Dondi, Riccardo

    The problem of publishing personal data without giving up privacy is becoming increasingly important. An interesting formalization recently proposed is the k-anonymity. This approach requires that the rows in a table are clustered in sets of size at least k and that all the rows in a cluster are related to the same tuple, after the suppression of some records. The problem has been shown to be NP-hard when the values are over a ternary alphabet, k = 3 and the rows length is unbounded. In this paper we give a lower bound on the approximation of two restrictions of the problem, when the records values are over a binary alphabet and k = 3, and when the records have length at most 8 and k = 4, showing that these restrictions of the problem are APX-hard.

  15. The nuclear 28S gene fragment D3 as species marker in oribatid mites (Acari, Oribatida) from German peatlands.

    Science.gov (United States)

    Lehmitz, Ricarda; Decker, Peter

    2017-03-01

    To make oribatid mites an applicable tool in monitoring programs it is necessary to find a molecular species marker that allows distinct, rapid and easy species identification. In previous studies, the common barcoding sequence COI showed to be too variable to serve as species marker in oribatid mites. The aim of the present study is to evaluate the potential use of the D3 region of the nuclear 28S rDNA gene for species identification. Therefore, we generated a reference DNA library of 28S D3 to identify specimens of the Oribatida from Germany, with focus on species occurring in peatlands being one of the most endangered habitats in Europe. New DNA sequences were obtained from 325 individuals and 64 species (58 genera, 34 families). By adding 28S D3-sequences from GenBank we altogether analysed 385 sequences from 89 German species, 32 of them restricted to peatlands and further 42 occurring in peatlands occasionally, representing 46 and 33% of the oribatids in German peatlands, respectively. P-distances were measured between species within families as well as for intraspecific divergence. 28S D3 showed low intraspecific genetic p-distances between 0 and 0.5%, interspecific distances within families varied between 0 and 9.7%. Most species pairs within families were further separated by one to four indels in addition to substitutions. Altogether, 93% of all analysed species are clearly delineated by 28S D3. Our study emphasises that 28S D3 rDNA is a useful barcode for the identification of oribatid mite specimens and represents an important step in building-up a comprehensive barcode library to allow metabarcoding analyses of environmental peatland samples for Oribatida in Germany as well as in Central Europe.

  16. Gene flow among wild and domesticated almond species: insights from chloroplast and nuclear markers

    Science.gov (United States)

    Delplancke, Malou; Alvarez, Nadir; Espíndola, Anahí; Joly, Hélène; Benoit, Laure; Brouck, Elise; Arrigo, Nils

    2012-01-01

    Hybridization has played a central role in the evolutionary history of domesticated plants. Notably, several breeding programs relying on gene introgression from the wild compartment have been performed in fruit tree species within the genus Prunus but few studies investigated spontaneous gene flow among wild and domesticated Prunus species. Consequently, a comprehensive understanding of genetic relationships and levels of gene flow between domesticated and wild Prunus species is needed. Combining nuclear and chloroplastic microsatellites, we investigated the gene flow and hybridization among two key almond tree species, the cultivated Prunus dulcis and one of the most widespread wild relative Prunus orientalis in the Fertile Crescent. We detected high genetic diversity levels in both species along with substantial and symmetric gene flow between the domesticated P. dulcis and the wild P. orientalis. These results were discussed in light of the cultivated species diversity, by outlining the frequent spontaneous genetic contributions of wild species to the domesticated compartment. In addition, crop-to-wild gene flow suggests that ad hoc transgene containment strategies would be required if genetically modified cultivars were introduced in the northwestern Mediterranean. PMID:25568053

  17. Phylogeny of Celastrus L. (Celastraceae) inferred from two nuclear and three plastid markers.

    Science.gov (United States)

    Mu, Xian-Yun; Zhao, Liang-Cheng; Zhang, Zhi-Xiang

    2012-09-01

    This is the first comprehensive molecular investigation of the genus Celastrus L. Phylogenetic relationships within the genus were assessed based on sequences of two nuclear (ETS, ITS) and three plastid (psbA-trnH, rpl16 and trnL-F) regions using the Bayesian inference and the maximum parsimony methods. Our results show that Celastrus, together with Tripterygium, formed a maximal supported clade. Within the cluster, Celastrus is composed of a basal clade and a core Celastrus clade, and the latter is consisted of six subclades. Relationships among species are more influenced by latitude than continental distribution patterns. The cauline cyme and lunate seeds are distinct characters to one of the maximal supported subclades. Their close relationship, similar geographical pattern and habitat imply that C. flagellaris may be a potential invasive species threatening C. scandens in North America. Celastrus leiocarpus, C. oblanceifolius and C. rugosus are confirmed as synonyms of C. punctatus, C. aculeatus and C. glaucophyllus, respectively. Discordance between the molecular data and previous morphology-based subgeneric classifications are noted. More works are needed to clarify the relationship between Celastrus and Tripterygium and the species within Celastrus.

  18. Really not god: Secularization and pragmatism in Gamblers Anonymous.

    Science.gov (United States)

    Browne, B R

    1994-09-01

    The paper argues that despite maintaining the image of a twelve-step organization, the central theme of the history of Gamblers Anonymous (GA) in the United States is the increasing secularization of the program of the recovery. The paper documents the increasing secularization and pragmatism of Gamblers Anonymous, as reflected in key documents, despite the spiritual vision of its founding member. The author speculates on why Gamblers Anonymous took a secularized development path. Further research is called for.

  19. Utility-preserving anonymization for health data publishing.

    Science.gov (United States)

    Lee, Hyukki; Kim, Soohyung; Kim, Jong Wook; Chung, Yon Dohn

    2017-07-11

    Publishing raw electronic health records (EHRs) may be considered as a breach of the privacy of individuals because they usually contain sensitive information. A common practice for the privacy-preserving data publishing is to anonymize the data before publishing, and thus satisfy privacy models such as k-anonymity. Among various anonymization techniques, generalization is the most commonly used in medical/health data processing. Generalization inevitably causes information loss, and thus, various methods have been proposed to reduce information loss. However, existing generalization-based data anonymization methods cannot avoid excessive information loss and preserve data utility. We propose a utility-preserving anonymization for privacy preserving data publishing (PPDP). To preserve data utility, the proposed method comprises three parts: (1) utility-preserving model, (2) counterfeit record insertion, (3) catalog of the counterfeit records. We also propose an anonymization algorithm using the proposed method. Our anonymization algorithm applies full-domain generalization algorithm. We evaluate our method in comparison with existence method on two aspects, information loss measured through various quality metrics and error rate of analysis result. With all different types of quality metrics, our proposed method show the lower information loss than the existing method. In the real-world EHRs analysis, analysis results show small portion of error between the anonymized data through the proposed method and original data. We propose a new utility-preserving anonymization method and an anonymization algorithm using the proposed method. Through experiments on various datasets, we show that the utility of EHRs anonymized by the proposed method is significantly better than those anonymized by previous approaches.

  20. Colour of the nucleus as a marker of nuclear hardness, diameter and central thickness

    Directory of Open Access Journals (Sweden)

    Gullapalli Vamsi

    1995-01-01

    Full Text Available Hundred and thirty patients, aged above 40 years, with senile cataract were examined. Age and colour were selected as the probable preoperative indicators of nuclear hardness. The lens material collected after manual extracapsular extraction was washed and the nucleus isolated. The diameter and central thickness of the nucleus were measured; the mean diameter and mean central thickness were 7.13 mm ± 0.76 and 3.05 mm ± 0.48, respectively. The hardness of the nucleus was measured with a lens guillotine designed by us. Regression analysis was applied to the parameters measured and these were compared with the colour and age. The parameters measured had the following relationship: Colour vs hardness (r value = 0.7569 (p < 0.001 Colour vs diameter (r value = 0.3962 (p < 0.001 Colour vs central thickness (r value = 0.4785 (p < 0.001 Age vs hardness (r value = -0.0499 (p > 0.05 Age vs diameter (r value = 0.0987 (p > 0.05 Age vs central thickness (r value = 0.1700 (p > 0.05 The values showed that colour had a statistically significant relationship with all the 3 parameters (p < 0.001, while age had no significant relationship with the same parameters. The results indicated that colour can be used more reliably to predict physical characteristics of the cataractous lens nucleus, the preoperative knowledge of which would help the surgeon in planning small-incision surgery including phacoemulsification.

  1. P-Sensitive K-Anonymity with Generalization Constraints

    OpenAIRE

    Alina Campan; Traian Marius Truta; Nicholas Cooper

    2010-01-01

    Numerous privacy models based on the k-anonymity property and extending the k-anonymity model have been introduced in the last few years in data privacy research: l-diversity, p-sensitive k-anonymity, (a, k) anonymity, t-closeness, etc. While differing in their methods and quality of their results, they all focus first on masking the data, and then protecting the quality of the data as a whole. We consider a new approach, where requirements on the amount of distortion allowed on the initial d...

  2. Identification of nuclear phosphoproteins as novel tobacco markers in mouse lung tissue following short-term exposure to tobacco smoke

    Directory of Open Access Journals (Sweden)

    Kanako Niimori-Kita

    2014-01-01

    Full Text Available Smoking is a risk factor for lung diseases, including chronic obstructive pulmonary disease and lung cancer. However, the molecular mechanisms mediating the progression of these diseases remain unclear. Therefore, we sought to identify signaling pathways activated by tobacco-smoke exposure, by analyzing nuclear phosphoprotein expression using phosphoproteomic analysis of lung tissue from mice exposed to tobacco smoke. Sixteen mice were exposed to tobacco smoke for 1 or 7 days, and the expression of phosphorylated peptides was analyzed by mass spectrometry. A total of 253 phosphoproteins were identified, including FACT complex subunit SPT16 in the 1-day exposure group, keratin type 1 cytoskeletal 18 (K18, and adipocyte fatty acid-binding protein, in the 7-day exposure group, and peroxiredoxin-1 (OSF3 and spectrin β chain brain 1 (SPTBN1, in both groups. Semi-quantitative analysis of the identified phosphoproteins revealed that 33 proteins were significantly differentially expressed between the control and exposed groups. The identified phosphoproteins were classified according to their biological functions. We found that the identified proteins were related to inflammation, regeneration, repair, proliferation, differentiation, morphogenesis, and response to stress and nicotine. In conclusion, we identified proteins, including OSF3 and SPTBN1, as candidate tobacco smoke-exposure markers; our results provide insights into the mechanisms of tobacco smoke-induced diseases.

  3. Order of the 17. of June 2010 approving the decision no 2010-DC-0182 by the Nuclear Safety Authority on the 18. of May 2010 specifying the limits of releases in the environment of liquid and gaseous effluents of civil base nuclear installations no 46, 74 and 100 operated by Electricite de France-Societe Anonyme (EDF-SA) on the district of Saint-Laurent-Nouan (Loir-et-Cher department); Arrete du 17 juin 2010 portant homologation de la decision no 2010-DC-0182 de l'Autorite de surete nucleaire du 18 mai 2010 fixant les limites de rejets dans l'environnement des effluents liquides et gazeux des installations nucleaires de base no 46, no 74 et no 100 exploitees par Electricite de France-Societe anonyme (EDF-SA) sur la commune de Saint-Laurent-Nouan (departement de Loir-et-Cher)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    This legal publication contains references to the different legal and official documents (codes, orders, minister's opinion, public surveys, administrative authorizations, local community opinion) at the root of this specification of limits related to releases in the environment of liquid and gaseous effluents of civil base nuclear installations operated by Electricite de France-Societe Anonyme (EDF-SA) on the district of Saint-Laurent-Nouan. Tables present the limits for different radioactive emissions (carbon 14, hydrogen 3, iodine, radioactive rare earths, and other alpha, beta and gamma emitters) from these different installations, but also the maximum admitted concentrations for gaseous chemical effluents (boric acid, hydrazine, morpholine, phosphates, nitrates, various metals, and so on). The limits for thermal releases are also specified

  4. Order of the 15. of September 2010 approving the decision no 2010-DC-0188 by the Nuclear Safety Authority on the 7. of July 2010 specifying to Electricite de France-Societe Anonyme (EDF-SA) the limits of releases in the environment of liquid and gaseous effluents for the operation of Flamanville 1 (INB n 108), Flamanville 2 (INB n 109) and Flamanville 3 (INB n 167) reactors

    International Nuclear Information System (INIS)

    2010-01-01

    This legal publication contains references to the different legal and official documents (codes, orders, minister's opinion, public surveys, administrative authorizations, local community opinion) at the root of this specification of limits related to releases in the environment of liquid and gaseous effluents by the three Flamanville nuclear reactors operated by Electricite de France-Societe Anonyme (EDF-SA). Tables present the limits for different gaseous and liquid radioactive emissions (carbon 14, hydrogen 3, iodine, radioactive rare earths, and other beta and gamma emitters) from these different installations, but also the maximum admitted concentrations for gaseous chemical effluents (boric acid, hydrazine hydrate, morpholine, phosphates, nitrates, various metals, and so on). The limits for thermal releases are also specified

  5. An Applet-based Anonymous Distributed Computing System.

    Science.gov (United States)

    Finkel, David; Wills, Craig E.; Ciaraldi, Michael J.; Amorin, Kevin; Covati, Adam; Lee, Michael

    2001-01-01

    Defines anonymous distributed computing systems and focuses on the specifics of a Java, applet-based approach for large-scale, anonymous, distributed computing on the Internet. Explains the possibility of a large number of computers participating in a single computation and describes a test of the functionality of the system. (Author/LRW)

  6. Anonymity and Openness in Donor Conception: the New Danish Model

    DEFF Research Database (Denmark)

    Herrmann, Janne Rothmar

    2013-01-01

    bank is based in Denmark and consequently anonymous sperm is also exported abroad, even into jurisdictions where anonymity is banned illegal. This commentary traces the raison d’être of anonymity in Danish law, accounts for the legal framework for the internet sale of sperm and examines the new Danish......Whereas the regulatory trend in many European countries has been a move towards openness in donation, Denmark has maintained the possibility of donating and receiving donated sperm completely anonymously. For that reason the supply of donated sperm remains so high that the world’s largest sperm...... model in donor conception which offers women/couples a choice of anonymity or openness in donation.This paper is based on my talk on June 20, 2013 at London School of Economics at the conference “New Families and Genetic Identities: Developments in law, policy and research” organised by the Morgan...

  7. Phylogeny and species delineation in European species of the genus Steganacarus (Acari, Oribatida) using mitochondrial and nuclear markers.

    Science.gov (United States)

    Kreipe, Victoria; Corral-Hernández, Elena; Scheu, Stefan; Schaefer, Ina; Maraun, Mark

    2015-06-01

    Species of the genus Steganacarus are soil-living oribatid mites (Acari, Phthiracaridae) with a ptychoid body. The phylogeny and species status of the species of Steganacarus are not resolved, some authors group all ten German species of Steganacarus within the genus Steganacarus whereas others split them into three subgenera, Steganacarus, Tropacarus and Atropacarus. Additionally, two species, S. magnus and T. carinatus, comprise morphotypes of questionable species status. We investigated the phylogeny and species status of ten European Steganacarus species, i.e. S. applicatus, S. herculeanus, S. magnus forma magna, S. magnus forma anomala, S. spinosus, Tropacarus brevipilus, T. carinatus forma carinata, T. carinatus forma pulcherrima, Atropacarus striculus and Rhacaplacarus ortizi. We used two molecular markers, a 251 bp fragment of the nuclear gene 28S rDNA (D3) and a 477 bp fragment of the mitochondrial COI region. The phylogeny based on a combined analysis of D3 and COI separated four subgenera (Steganacarus, Tropacarus and Atropacarus, Rhacaplacarus) indicating that they form monophyletic groups. The COI region separated all ten species of the genus Steganacarus and showed variation within some species often correlating with the geographic origin of the species. Resolution of the more conserved D3 region was limited, indicating that radiation events are rather recent. Overall, our results indicate that both genes alone cannot be used for phylogeny and barcoding since variation is too low in D3 and too high in COI. However, when used in combination these genes provide reliable insight into the phylogeny, radiation and species status of taxa of the genus Steganacarus.

  8. A Differentiated Anonymity Algorithm for Social Network Privacy Preservation

    Directory of Open Access Journals (Sweden)

    Yuqin Xie

    2016-12-01

    Full Text Available Devising methods to publish social network data in a form that affords utility without compromising privacy remains a longstanding challenge, while many existing methods based on k-anonymity algorithms on social networks may result in nontrivial utility loss without analyzing the social network topological structure and without considering the attributes of sparse distribution. Toward this objective, we explore the impact of the attributes of sparse distribution on data utility. Firstly, we propose a new utility metric that emphasizes network structure distortion and attribute value loss. Furthermore, we design and implement a differentiated k-anonymity l-diversity social network anonymity algorithm, which seeks to protect users’ privacy in social networks and increase the usability of the published anonymized data. Its key idea is that it divides a node into two child nodes and only anonymizes sensitive values to satisfy anonymity requirements. The evaluation results show that our method can effectively improve the data utility as compared to generalized anonymizing algorithms.

  9. Alcoholics Anonymous and nursing. Lessons in holism and spiritual care.

    Science.gov (United States)

    McGee, E M

    2000-03-01

    Alcoholic Anonymous (AA) is a worldwide, million-member organization that has assisted countless alcoholics to achieve sobriety through a spiritual program of recovery from alcoholism. Based on spiritual principles known as the "Twelve Steps" and "Twelve Traditions," AA has provided a model for other recovery programs such as Narcotics Anonymous (NA), Gamblers Anonymous (GA), and Sex and Love Addicts Anonymous (SLAA). Recovery in AA appears to involve a process of self-transcendence. In recent years, nursing scholars have increasingly explored the concepts of self-transcendence and spirituality as they apply to nursing theory and practice. This article explores the roots and spiritual dimensions of 12-step recovery programs. It further explores the ways in which theoretical and clinical knowledge about the delivery of spiritual care interventions may be gained from an understanding of AA's spiritual approach to recovery.

  10. Unraveling an Old Cloak: k-anonymity for Location Privacy

    OpenAIRE

    Shokri, Reza; Troncoso, Carmela; Diaz, Claudia; Freudiger, Julien; Hubaux, Jean-Pierre

    2010-01-01

    There is a rich collection of literature that aims at protecting the privacy of users querying location-based services. One of the most popular location privacy techniques consists in cloaking users' locations such that k users appear as potential senders of a query, thus achieving k-anonymity. This paper analyzes the effectiveness of k-anonymity approaches for protecting location privacy in the presence of various types of adversaries. The unraveling of the scheme unfolds the inconsistency b...

  11. System for Anonymous Data Collection Based on Group Signature Scheme

    Directory of Open Access Journals (Sweden)

    David Troják

    2016-01-01

    Full Text Available This paper deals with an anonymous data collection in the Internet of Things (IoT. the privacy and anonymity of the data source is important for many IoT applications, such as in agriculture, health, and automotive. the proposed data‑collection system provides anonymity for the data sources by applying a cooperation group scheme. the group scheme also provides a low power consumption. the system is built upon the Tor (The Onion Router anonymous network, which is a part of the Internet darknet. the proposed system was designed for the Android devices on the client side and for Java environment on the server side. We evaluated the anonymous data collection in a real‑use scenario that covers selected data acquisition (e.g. signal strength from smartphones triggered by their geographical location change. the results show that the proposed system provides the sufficient data source anonymity, an effective revocation, a low computational cost and a low overhead.

  12. Contrasting genetic structure between mitochondrial and nuclear markers in the dengue fever mosquito from Rio de Janeiro: implications for vector control.

    Science.gov (United States)

    Rašić, Gordana; Schama, Renata; Powell, Rosanna; Maciel-de Freitas, Rafael; Endersby-Harshman, Nancy M; Filipović, Igor; Sylvestre, Gabriel; Máspero, Renato C; Hoffmann, Ary A

    2015-10-01

    Dengue is the most prevalent global arboviral disease that affects over 300 million people every year. Brazil has the highest number of dengue cases in the world, with the most severe epidemics in the city of Rio de Janeiro (Rio). The effective control of dengue is critically dependent on the knowledge of population genetic structuring in the primary dengue vector, the mosquito Aedes aegypti. We analyzed mitochondrial and nuclear genomewide single nucleotide polymorphism markers generated via Restriction-site Associated DNA sequencing, as well as traditional microsatellite markers in Ae. aegypti from Rio. We found four divergent mitochondrial lineages and a strong spatial structuring of mitochondrial variation, in contrast to the overall nuclear homogeneity across Rio. Despite a low overall differentiation in the nuclear genome, we detected strong spatial structure for variation in over 20 genes that have a significantly altered expression in response to insecticides, xenobiotics, and pathogens, including the novel biocontrol agent Wolbachia. Our results indicate that high genetic diversity, spatially unconstrained admixing likely mediated by male dispersal, along with locally heterogeneous genetic variation that could affect insecticide resistance and mosquito vectorial capacity, set limits to the effectiveness of measures to control dengue fever in Rio.

  13. The comparison of nuclear ubiquitous casein and cyclin-dependent kinases substrate (NUCKS) with Ki67 proliferation marker expression in common skin tumors.

    Science.gov (United States)

    Zduniak, Krzysztof; Agrawal, Siddarth; Symonowicz, Krzysztof; Jurczyszyn, Kamil; Ziółkowski, Piotr

    2014-03-01

    Nuclear ubiquitous casein and cyclin-dependent kinases substrate (NUCKS) is a chromosomal protein of unknown function. Its amino acid composition and structure of its DNA binding domain resemble those of high mobility group A (HMGA) proteins which are associated with various malignancies. Since changes in expression of HMGA are considered as a marker of tumor progression, it is possible that similar changes in expression of NUCKS could be a useful tool in diagnosis of malignant skin tumors. To investigate this assumption we used specific antibodies against NUCKS for immunohistochemistry of squamous (SCC) and basal cell carcinoma (BCC) as well as keratoacanthoma (KA). We found high expression of NUCKS in nuclei of SCC and BCC cells which exceeded expression of the well-known proliferation marker Ki67. Expression of NUCKS in benign KA was much below that of malignant tumors. With the present study and based on our previous experience we would like to suggest the NUCKS protein as a novel proliferation marker for immunohistochemical evaluation of formalin-fixed and paraffin-embedded skin tumor specimens. We would like to emphasize that NUCKS abundance in malignant skin tumors is higher than that of the well-known proliferation marker Ki67, thus allowing more precise assessment of tumor proliferation potential.

  14. Efficient and anonymous two-factor user authentication in wireless sensor networks: achieving user anonymity with lightweight sensor computation.

    Science.gov (United States)

    Nam, Junghyun; Choo, Kim-Kwang Raymond; Han, Sangchul; Kim, Moonseong; Paik, Juryon; Won, Dongho

    2015-01-01

    A smart-card-based user authentication scheme for wireless sensor networks (hereafter referred to as a SCA-WSN scheme) is designed to ensure that only users who possess both a smart card and the corresponding password are allowed to gain access to sensor data and their transmissions. Despite many research efforts in recent years, it remains a challenging task to design an efficient SCA-WSN scheme that achieves user anonymity. The majority of published SCA-WSN schemes use only lightweight cryptographic techniques (rather than public-key cryptographic techniques) for the sake of efficiency, and have been demonstrated to suffer from the inability to provide user anonymity. Some schemes employ elliptic curve cryptography for better security but require sensors with strict resource constraints to perform computationally expensive scalar-point multiplications; despite the increased computational requirements, these schemes do not provide user anonymity. In this paper, we present a new SCA-WSN scheme that not only achieves user anonymity but also is efficient in terms of the computation loads for sensors. Our scheme employs elliptic curve cryptography but restricts its use only to anonymous user-to-gateway authentication, thereby allowing sensors to perform only lightweight cryptographic operations. Our scheme also enjoys provable security in a formal model extended from the widely accepted Bellare-Pointcheval-Rogaway (2000) model to capture the user anonymity property and various SCA-WSN specific attacks (e.g., stolen smart card attacks, node capture attacks, privileged insider attacks, and stolen verifier attacks).

  15. Genetic differentiation in the soil-feeding termite Cubitermes sp. affinis subarquatus: occurrence of cryptic species revealed by nuclear and mitochondrial markers

    Directory of Open Access Journals (Sweden)

    Livet Alexandre

    2006-11-01

    Full Text Available Abstract Background Soil-feeding termites are particularly interesting models for studying the effects of fragmentation, a natural or anthropic phenomenon described as promoting genetic differentiation. However, studying the link between fragmentation and genetics requires a method for identifying species unambiguously, especially when morphological diagnostic characters are lacking. In humivorous termites, which contribute to the fertility of tropical soils, molecular taxonomy and phylogenetic relationships are rarely studied, though mitochondrial and nuclear molecular markers are widely used in studies of pest termites. Here, we attempt to clarify the taxonomy of soil-feeding colonies collected throughout the naturally fragmented Lopé Reserve area (Gabon and morphologically affiliated to Cubitermes sp. affinis subarquatus. The mitochondrial gene of cytochrome oxidase II (COII, the second nuclear rDNA internal transcribed spacer (ITS2 and five microsatellites were analyzed in 19 colonies. Results Bayesian Inference, Maximum Likelihood and Maximum Parsimony phylogenetic analyses, which were applied to the COII and ITS2 sequences, and Neighbor-Joining reconstructions, applied to the microsatellite data, reveal four major lineages in the Cubitermes sp. affinis subarquatus colonies. The concordant genealogical pattern of these unlinked markers strongly supports the existence of four cryptic species. Three are sympatric in the Reserve and are probably able to disperse within a mosaic of forests of variable ages and savannahs. One is limited to a very restricted gallery forest patch located in the North, outside the Reserve. Conclusion Our survey highlights the value of combined mitochondrial and nuclear markers for exploring unknown groups such as soil-feeding termites, and their relevance for resolving the taxonomy of organisms with ambiguous morphological diagnostic characters.

  16. Humoral markers of active Epstein-Barr virus infection associate with anti-extractable nuclear antigen autoantibodies and plasma galectin-3 binding protein in systemic lupus erythematosus.

    Science.gov (United States)

    Rasmussen, N S; Nielsen, C T; Houen, G; Jacobsen, S

    2016-12-01

    We investigated if signs of active Epstein-Barr virus and cytomegalovirus infections associate with certain autoantibodies and a marker of type I interferon activity in patients with systemic lupus erythematosus. IgM and IgG plasma levels against Epstein-Barr virus early antigen diffuse and cytomegalovirus pp52 were applied as humoral markers of ongoing/recently active Epstein-Barr virus and cytomegalovirus infections, respectively. Plasma galectin-3 binding protein served as a surrogate marker of type I interferon activity. The measurements were conducted in 57 systemic lupus erythematosus patients and 29 healthy controls using ELISAs. Regression analyses and univariate comparisons were performed for associative evaluation between virus serology, plasma galectin-3 binding protein and autoantibodies, along with other clinical and demographic parameters. Plasma galectin-3 binding protein concentrations were significantly higher in systemic lupus erythematosus patients (P = 0.009) and associated positively with Epstein-Barr virus early antigen diffuse-directed antibodies and the presence of autoantibodies against extractable nuclear antigens in adjusted linear regressions (B = 2.02 and 2.02, P = 0.02 and P = 0.002, respectively). Furthermore, systemic lupus erythematosus patients with anti-extractable nuclear antigens had significantly higher antibody levels against Epstein-Barr virus early antigen diffuse (P = 0.02). Our study supports a link between active Epstein-Barr virus infections, positivity for anti-extractable nuclear antigens and increased plasma galectin-3 binding protein concentrations/type I interferon activity in systemic lupus erythematosus patients. © The Author(s) 2016.

  17. Interim policy on establishment and operation of internet open, anonymous information servers and services

    OpenAIRE

    Acting Dean of Computer and Information Services

    1995-01-01

    Purpose. To establish interim NPS general policy regarding establishment and operation of Open, Anonymous Information Servers and Services, such as World Wide Web (http), Gopher, Anonymous FTP, etc...

  18. Does anonymity increase the reporting of mental health symptoms?

    Science.gov (United States)

    Fear, Nicola T; Seddon, Rachel; Jones, Norman; Greenberg, Neil; Wessely, Simon

    2012-09-17

    There is no doubt that the perceived stigma of having a mental disorder acts as a barrier to help seeking. It is possible that personnel may be reluctant to admit to symptoms suggestive of poor mental health when such data can be linked to them, even if their personal details are only used to help them access further care. This may be particularly relevant because individuals who have a mental health problem are more likely to experience barriers to care and hold stigmatizing beliefs. If that is the case, then mental health screening programmers may not be effective in detecting those most in need of care. We aimed to compare mental health symptom reporting when using an anonymous versus identifiable questionnaire among UK military personnel on deployment in Iraq. Survey among UK military personnel using two questionnaires, one was anonymous (n = 315) and one collected contact details (i.e. identifiable, n = 296). Distribution was by alternate allocation. Data were collected in Iraq during January-February 2009. No significant difference in the reporting of symptoms of common mental disorders was found (18.1% of identifiable vs. 22.9% of anonymous participants). UK military personnel were more likely to report sub-threshold and probable PTSD when completing questionnaires anonymously (sub-threshold PTSD: 2.4% of identifiable vs. 5.8% of anonymous participants; probable PTSD: 1.7% of identifiable vs. 4.8% of anonymous participants). Of the 11 barriers to care and perceived social stigma statements considered, those completing the anonymous questionnaire compared to those completing the identifiable questionnaire were more likely to endorse three statements: "leaders discourage the use of mental health services" (9.3% vs. 4.6%), "it would be too embarrassing" (41.6% vs. 32.5%) and "I would be seen as weak" (46.6% vs. 34.2%). We found a significant effect on the reporting of sub-threshold and probable PTSD and certain stigmatizing beliefs (but not common mental

  19. Does anonymity increase the reporting of mental health symptoms?

    Directory of Open Access Journals (Sweden)

    Fear Nicola T

    2012-09-01

    Full Text Available Abstract Background There is no doubt that the perceived stigma of having a mental disorder acts as a barrier to help seeking. It is possible that personnel may be reluctant to admit to symptoms suggestive of poor mental health when such data can be linked to them, even if their personal details are only used to help them access further care. This may be particularly relevant because individuals who have a mental health problem are more likely to experience barriers to care and hold stigmatizing beliefs. If that is the case, then mental health screening programmers may not be effective in detecting those most in need of care. We aimed to compare mental health symptom reporting when using an anonymous versus identifiable questionnaire among UK military personnel on deployment in Iraq. Methods Survey among UK military personnel using two questionnaires, one was anonymous (n = 315 and one collected contact details (i.e. identifiable, n = 296. Distribution was by alternate allocation. Data were collected in Iraq during January-February 2009. Results No significant difference in the reporting of symptoms of common mental disorders was found (18.1% of identifiable vs. 22.9% of anonymous participants. UK military personnel were more likely to report sub-threshold and probable PTSD when completing questionnaires anonymously (sub-threshold PTSD: 2.4% of identifiable vs. 5.8% of anonymous participants; probable PTSD: 1.7% of identifiable vs. 4.8% of anonymous participants. Of the 11 barriers to care and perceived social stigma statements considered, those completing the anonymous questionnaire compared to those completing the identifiable questionnaire were more likely to endorse three statements: “leaders discourage the use of mental health services” (9.3% vs. 4.6%, “it would be too embarrassing” (41.6% vs. 32.5% and “I would be seen as weak” (46.6% vs. 34.2%. Conclusions We found a significant effect on the reporting of sub

  20. Anonymity in Peer-assisted CDNs: Inference Attacks and Mitigation

    Directory of Open Access Journals (Sweden)

    Jia Yaoqi

    2016-10-01

    Full Text Available The peer-assisted CDN is a new content distribution paradigm supported by CDNs (e.g., Akamai, which enables clients to cache and distribute web content on behalf of a website. Peer-assisted CDNs bring significant bandwidth savings to website operators and reduce network latency for users. In this work, we show that the current designs of peer-assisted CDNs expose clients to privacy-invasive attacks, enabling one client to infer the set of browsed resources of another client. To alleviate this, we propose an anonymous peer-assisted CDN (APAC, which employs content delivery while providing initiator anonymity (i.e., hiding who sends the resource request and responder anonymity (i.e., hiding who responds to the request for peers. APAC can be a web service, compatible with current browsers and requiring no client-side changes. Our anonymity analysis shows that our APAC design can preserve a higher level of anonymity than state-of-the-art peer-assisted CDNs. In addition, our evaluation demonstrates that APAC can achieve desired performance gains.

  1. Criminal offenses in gamblers anonymous and hospital treated pathological gamblers.

    Science.gov (United States)

    Blaszczynski, A P; McConaghy, N

    1994-06-01

    The purpose of this study was to compare the nature and prevalence of gambling and non-gambling related offenses in samples of pathological gamblers seeking behavioural treatment from a hospital-based program and those attending Gamblers Anonymous. A semi-structured interview schedule obtaining demographic data and details of the nature, frequency, and consequent legal action of criminal offenses committed was administered to 152 consecutive hospital treated pathological gamblers, and 154 Gamblers Anonymous attendees who volunteered to participate in the study. Of the total sample, 59% admitted a gambling-related offense, and 23% to a conviction. There was no difference in the proportion of hospital treated and Gamblers Anonymous subjects who offended. The most common gambling-related offenses were larceny, embezzlement and misappropriation. Gamblers committed a median of ten offenses over an average ten year period of pathological gambling with a median value of $ A 300(1) per offense. The median value for each non-gambling-related offense was $ A 130. Except for the significantly older mean age of Gamblers Anonymous subjects, hospital treated gamblers did not differ from Gamblers Anonymous attenders on relevant demographic features or parameters of gambling behaviour. Findings were interpreted to suggest a possible causal link between pathological gambling and the commission of non-violent property offenses.

  2. How to kill gamete donation: retrospective legislation and donor anonymity.

    Science.gov (United States)

    Pennings, Guido

    2012-10-01

    Victoria (Australia) is considering retrospective legislation on the abolition of gamete donor anonymity. Retrospective legislation evokes many negative emotions mainly because it is considered unfair. It also makes it impossible for citizens to organize their life with reasonable certainty of the consequences. Introduction of this law for donor anonymity is defended by the right of the child to know its genetic origins. Against this law, people appeal to the right to privacy and confidentiality of the donor. This paper analyses the arguments for and against a retrospective law on donor anonymity by looking at the conditions that should be respected when two principles (the donor's right to privacy and the child's right to genetic information) have to be balanced. It is concluded that the justification for introducing retrospective law is lacking: the conditions are not fulfilled. Moreover, retroactive laws in the context of gamete donation may jeopardize the whole practice by destroying the trust of candidate donors and recipients in the government.

  3. Anonymous pastoral care for problems pertaining to sexuality.

    Science.gov (United States)

    van Drie, A; Ganzevoort, R R; Spiering, M

    2014-12-01

    Anonymous pastoral care is one of the options for help in problems pertaining to sexuality. This paper explores the topics they seek help for, the religious aspects involved, and the relation between the normativity of their church tradition on the one hand and sexual and spiritual health criteria on the other. We analyzed helpseeking questions of two protestant Christian organizations in the Netherlands providing anonymous pastoral care: Refoweb and EO-Nazorg. Sexual themes were addressed in 19 and 2.3 % of the submitted questions, respectively. Of the helpseekers, 56 % is female, 15 % male, and 29 % unknown. Questions and problems for which people seek anonymous pastoral care focus primarily on premarital abstinence, gender roles, contraception, sexual orientation and masturbation. The authority of the Bible seems to be important for questioners, especially when dealing with ethical questions. Different relations between the normativity of the church tradition and sexual and spiritual health are discussed.

  4. Verifying Anonymous Credential Systems in Applied Pi Calculus

    Science.gov (United States)

    Li, Xiangxi; Zhang, Yu; Deng, Yuxin

    Anonymous credentials are widely used to certify properties of a credential owner or to support the owner to demand valuable services, while hiding the user's identity at the same time. A credential system (a.k.a. pseudonym system) usually consists of multiple interactive procedures between users and organizations, including generating pseudonyms, issuing credentials and verifying credentials, which are required to meet various security properties. We propose a general symbolic model (based on the applied pi calculus) for anonymous credential systems and give formal definitions of a few important security properties, including pseudonym and credential unforgeability, credential safety, pseudonym untraceability. We specialize the general formalization and apply it to the verification of a concrete anonymous credential system proposed by Camenisch and Lysyanskaya. The analysis is done automatically with the tool ProVerif and several security properties have been verified.

  5. Structure and Anonymity of the Bitcoin Transaction Graph

    Directory of Open Access Journals (Sweden)

    Kay Hamacher

    2013-05-01

    Full Text Available The Bitcoin network of decentralized payment transactions has attracted a lot of attention from both Internet users and researchers in recent years. Bitcoin utilizes a peer-to-peer network to issue anonymous payment transactions between different users. In the currently used Bitcoin clients, the full transaction history is available at each node of the network to prevent double spending without the need for a central authority, forming a valuable source for empirical research on network structure, network dynamics, and the implied anonymity challenges, as well as guidance on the future evolution of complex payment systems. We found dynamical effects of which some increase anonymity while others decrease it. Most importantly, several parameters of the Bitcoin transaction graph seem to have become stationary over the last 12–18 months. We discuss the implications.

  6. Secure and Efficient Anonymous Authentication Scheme in Global Mobility Networks

    Directory of Open Access Journals (Sweden)

    Jun-Sub Kim

    2013-01-01

    Full Text Available In 2012, Mun et al. pointed out that Wu et al.’s scheme failed to achieve user anonymity and perfect forward secrecy and disclosed the passwords of legitimate users. And they proposed a new enhancement for anonymous authentication scheme. However, their proposed scheme has vulnerabilities that are susceptible to replay attack and man-in-the-middle attack. It also incurs a high overhead in the database. In this paper, we examine the vulnerabilities in the existing schemes and the computational overhead incurred in the database. We then propose a secure and efficient anonymous authentication scheme for roaming service in global mobility network. Our proposed scheme is secure against various attacks, provides mutual authentication and session key establishment, and incurs less computational overhead in the database than Mun et al.'s scheme.

  7. Authority and Hierarchy within Anonymous Internet Relay Chat Networks

    Directory of Open Access Journals (Sweden)

    Stewart Kenton Bertram

    2015-09-01

    Full Text Available 'The protest group Anonymous has emerged as one of the most significant social movements of recent years, announcing their arrival as a globally recognized brand with regular disruptive cyber attacks and the leak of large volumes of sensitive data. Despite the obvious significance of Anonymous, to date, little academic research has been focused on what role hierarchy and internal authority play (if any within the group. Bespoke software was used to structure over 5000 examples of IRC log files, so that a base line descriptive statistical picture could be drawn, as well as a more granular enumeration of the privileges associated with individual users.'

  8. Anonymizing patient genomic data for public sharing association studies.

    Science.gov (United States)

    Fernandez-Lozano, Carlos; Lopez-Campos, Guillermo; Seoane, Jose A; Lopez-Alonso, Victoria; Dorado, Julian; Martín-Sanchez, Fernando; Pazos, Alejandro

    2013-01-01

    The development of personalized medicine is tightly linked with the correct exploitation of molecular data, especially those associated with the genome sequence along with these use of genomic data there is an increasing demand to share these data for research purposes. Transition of clinical data to research is based in the anonymization of these data so the patient cannot be identified, the use of genomic data poses a great challenge because its nature of identifying data. In this work we have analyzed current methods for genome anonymization and propose a one way encryption method that may enable the process of genomic data sharing accessing only to certain regions of genomes for research purposes.

  9. Nuclear species-diagnostic SNP markers mined from 454 amplicon sequencing reveal admixture genomic structure of modern citrus varieties.

    Directory of Open Access Journals (Sweden)

    Franck Curk

    Full Text Available Most cultivated Citrus species originated from interspecific hybridisation between four ancestral taxa (C. reticulata, C. maxima, C. medica, and C. micrantha with limited further interspecific recombination due to vegetative propagation. This evolution resulted in admixture genomes with frequent interspecific heterozygosity. Moreover, a major part of the phenotypic diversity of edible citrus results from the initial differentiation between these taxa. Deciphering the phylogenomic structure of citrus germplasm is therefore essential for an efficient utilization of citrus biodiversity in breeding schemes. The objective of this work was to develop a set of species-diagnostic single nucleotide polymorphism (SNP markers for the four Citrus ancestral taxa covering the nine chromosomes, and to use these markers to infer the phylogenomic structure of secondary species and modern cultivars. Species-diagnostic SNPs were mined from 454 amplicon sequencing of 57 gene fragments from 26 genotypes of the four basic taxa. Of the 1,053 SNPs mined from 28,507 kb sequence, 273 were found to be highly diagnostic for a single basic taxon. Species-diagnostic SNP markers (105 were used to analyse the admixture structure of varieties and rootstocks. This revealed C. maxima introgressions in most of the old and in all recent selections of mandarins, and suggested that C. reticulata × C. maxima reticulation and introgression processes were important in edible mandarin domestication. The large range of phylogenomic constitutions between C. reticulata and C. maxima revealed in mandarins, tangelos, tangors, sweet oranges, sour oranges, grapefruits, and orangelos is favourable for genetic association studies based on phylogenomic structures of the germplasm. Inferred admixture structures were in agreement with previous hypotheses regarding the origin of several secondary species and also revealed the probable origin of several acid citrus varieties. The developed species

  10. A codon-optimized bacterial antibiotic gene used as selection marker for stable nuclear transformation in the marine red alga Pyropia yezoensis.

    Science.gov (United States)

    Uji, Toshiki; Hirata, Ryo; Fukuda, Satoru; Mizuta, Hiroyuki; Saga, Naotsune

    2014-06-01

    Marine macroalgae play an important role in marine coastal ecosystems and are widely used as sea vegetation foodstuffs and for industrial purposes. Therefore, there have been increased demands for useful species and varieties of these macroalgae. However, genetic transformation in macroalgae has not yet been established. We have developed a dominant selection marker for stable nuclear transformation in the red macroalga Pyropia yezoensis. We engineered the coding region of the aminoglycoside phosphotransferase gene aph7″ from Streptomyces hygroscopicus to adapt codon usage of the nuclear genes of P. yezoensis. We designated this codon-optimized aph7″ gene as PyAph7. After bombarding P. yezoensis cells with plasmids containing PyAph7 under the control of their endogenous promoter, 1.9 thalli (or individuals) of hygromycin-resistant strains were isolated from a 10-mm square piece of the bombarded thallus. These transformants were stably maintained throughout the asexual life cycle. Stable expression of PyAph7was verified using Southern blot analysis and genomic PCR and RT-PCR analyses. PyAph7 proved to be a new versatile tool for stable nuclear transformation in P. yezoensis.

  11. Forming Circle Formations of Anonymous Mobile Agents With Order Preservation

    NARCIS (Netherlands)

    Wang, Chen; Xie, Guangming; Cao, Ming

    2013-01-01

    We propose distributed control laws for a group of anonymous mobile agents to form desired circle formations when the agents move in the one-dimensional space of a circle. The agents are modeled by kinematic points. They share the common knowledge of the orientation of the circle, but are oblivious

  12. Leader Election in Anonymous Rings: Franklin Goes Probabilistic

    NARCIS (Netherlands)

    Bakhshi, Rena; Fokkink, Wan; Pang, Jun; van de Pol, Jan Cornelis; Ausiello, G.; Karhumäki, J.; Mauri, G.; Ong, L.

    2008-01-01

    We present a probabilistic leader election algorithm for anonymous, bidirectional, asynchronous rings. It is based on an algorithm from Franklin, augmented with random identity selection, hop counters to detect identity clashes, and round numbers modulo 2. As a result, the algorithm is finite-state,

  13. Leader election in anonymous rings: Franklin goes probabilistic

    NARCIS (Netherlands)

    R. Bakhshi; W.J. Fokkink (Wan); J. Pang; J.C. van de Pol (Jaco); G. Ausiello

    2008-01-01

    htmlabstractWe present a probabilistic leader election algorithm for anonymous, bidirectional, asynchronous rings. It is based on an algorithm from Franklin, augmented with random identity selection, hop counters to detect identity clashes, and round numbers modulo 2. As a result, the algorithm is

  14. Simplifying Itai-Rodeh Leader Election for Anonymous Rings

    NARCIS (Netherlands)

    Fokkink, W.J.; Pang, J.

    2005-01-01

    We present two probabilistic leader election algorithms for anonymous unidirectional rings with FIFO channels, based on an algorithm from Itai and Rodeh [A. Itai and M. Rodeh. Symmetry breaking in distributive networks. In Proc. FOCS'81, pp. 150-158. IEEE Computer Society, 1981]. In contrast to the

  15. Anonymity and Openness in Donor Conception: the New Danish Model

    DEFF Research Database (Denmark)

    Herrmann, Janne Rothmar

    2013-01-01

    model in donor conception which offers women/couples a choice of anonymity or openness in donation.This paper is based on my talk on June 20, 2013 at London School of Economics at the conference “New Families and Genetic Identities: Developments in law, policy and research” organised by the Morgan...

  16. Circle formation for anonymous mobile robots with order preservation

    NARCIS (Netherlands)

    Wang, Chen; Cao, Ming; Xie, Guangming; Wang, Long

    2012-01-01

    This paper proposes a distributed control law for a group of mobile robots to form any given formation on a circle of a prescribed radius. The robots are modeled by point masses with the constraint that all of them can move only on the circle. In particular, robots are oblivious, anonymous, and

  17. Anonymity versus Perceived Patron Identity in Virtual Reference Transcripts

    Science.gov (United States)

    Roper, Kristin Grabarek; Sobel, Karen

    2012-01-01

    Librarians who provide virtual reference services often perceive that their patrons self-identify to some degree, even when transactions are anonymous. They also develop a sense of patrons' greatest research-related needs over time. In this article, two librarians analyze two years' worth of virtual reference transcripts to determine what patrons…

  18. Who Goes There? Staying Anonymous on the Internet

    Science.gov (United States)

    Descy, Don E.

    2009-01-01

    Privacy is a thing of the past. Monitoring is everywhere. If one is looking at this online, the author is sure that lots of information has been stored and linked to anyone about that action. Nevertheless, at least people can try to play with "their" minds and surf the web anonymously. In this article, the author discusses ways to try to hide…

  19. Does spousal participation in Gamblers Anonymous benefit compulsive gamblers?

    Science.gov (United States)

    Johnson, E E; Nora, R M

    1992-12-01

    Extent of gambling-free periods was compared for 90 compulsive gamblers, 44 with spouses who participated in Gamblers Anonymous and 46 with spouses who did not. Although the results were in the direction of a beneficial effect of spousal participation, the relationship was statistically nonsignificant.

  20. Gamblers anonymous and cognitive-behavioral therapies for pathological gamblers.

    Science.gov (United States)

    Petry, Nancy M

    2005-01-01

    Numerous types of treatments for pathological gambling have been described, but two of the most common are Gamblers Anonymous (GA) and cognitive-behavioral therapy. This paper describes some outcome data associated with the two approaches. It also reviews evidence suggesting that a combined intervention may enhance therapy engagement and reduce relapse rates.

  1. Effectiveness of Parents' Anonymous in Reducing Child Abuse.

    Science.gov (United States)

    Post-Kammer, Phyllis

    1988-01-01

    Studied Parents Anonymous (PA), organization created to provide support group services for families and to develop community awareness of child abuse and neglect, in order to describe function of PA to school counselors for their use as referral source and to determine program's impact on parents' self-concept, understanding of children, and…

  2. Anonymous living liver donation: donor profiles and outcomes.

    Science.gov (United States)

    Reichman, T W; Fox, A; Adcock, L; Wright, L; Abbey, S E; Levy, G; Grant, D R

    2010-09-01

    There are no published series of the assessment process, profiles and outcomes of anonymous, directed or nondirected live liver donation. The outcomes of 29 consecutive potential anonymous liver donors at our center were assessed. We used our standard live liver assessment process, augmented with the following additional acceptance criteria: a logical rationale for donation, a history of social altruism, strong social supports and a willingness to maintain confidentiality of patient information. Seventeen potential donors were rejected and 12 donors were ultimately accepted (six male, six female). All donors were strongly motivated by a desire and sense of responsibility to help others. Four donations were directed toward recipients who undertook media appeals. The donor operations included five left lateral segmentectomies and seven right hepatectomies. The overall donor morbidity was 40% with one patient having a transient Clavien level 3 complication (a pneumothorax). All donors are currently well. None expressed regret about their decision to donate, and all volunteered the opinion that donation had improved their lives. The standard live liver donor assessment process plus our additional requirements appears to provide a robust assessment process for the selection of anonymous live liver donors. Acceptance of anonymous donors enlarges the donor liver pool. © 2010 The Authors Journal compilation © 2010 The American Society of Transplantation and the American Society of Transplant Surgeons.

  3. Father-Daughter Incest: Data from an Anonymous Computerized Survey

    Science.gov (United States)

    Stroebel, Sandra S.; O'Keefe, Stephen L.; Beard, Keith W.; Kuo, Shih-Ya; Swindell, Samuel V. S.; Kommor, Martin J.

    2012-01-01

    Retrospective data were entered anonymously by 1,521 adult women using computer-assisted self-interview. Nineteen were classified as victims of father-daughter incest, and 241 were classified as victims of sexual abuse by an adult other than their father before reaching 18 years of age. The remaining 1,261 served as controls. Incest victims were…

  4. A reciprocal framework for spatial K-anonymity

    KAUST Repository

    Ghinita, Gabriel

    2010-05-01

    Spatial K-anonymity (SKA) exploits the concept of K-anonymity in order to protect the identity of users from location-based attacks. The main idea of SKA is to replace the exact location of a user U with an anonymizing spatial region (ASR) that contains at least K-1 other users, so that an attacker can pinpoint U with probability at most 1/K. Simply generating an ASR that includes K users does not guarantee SKA. Previous work defined the reciprocity property as a sufficient condition for SKA. However, the only existing reciprocal method, Hilbert Cloak, relies on a specialized data structure. In contrast, we propose a general framework for implementing reciprocal algorithms using any existing spatial index on the user locations. We discuss ASR construction methods with different tradeoffs on effectiveness (i.e., ASR size) and efficiency (i.e., construction cost). Then, we present case studies of applying our framework on top of two popular spatial indices (namely, R*-trees and Quad-trees). Finally, we consider the case where the attacker knows the query patterns of each user. The experimental results verify that our methods outperform Hilbert Cloak. Moreover, since we employ general-purpose spatial indices, the proposed system is not limited to anonymization, but supports conventional spatial queries as well. © 2009 Elsevier B.V. All rights reserved.

  5. Policy-Aware Sender Anonymity in Location-Based Services

    Science.gov (United States)

    Vyas, Avinash

    2011-01-01

    Sender anonymity in Location-based services (LBS) refers to hiding the identity of a mobile device user who sends requests to the LBS provider for services in her proximity (e.g. "find the nearest gas station etc."). The goal is to keep the requester's interest private even from attackers who (via hacking or subpoenas) gain access to the LBS…

  6. Visibility and anonymity effects on attraction and group cohesiveness

    NARCIS (Netherlands)

    Lea, Martin; Spears, Russell; Watt, Susan E.

    2007-01-01

    This study investigated attraction and group cohesiveness under different visibility and anonymity conditions for social categories that differed in their capacity to be visually cued. Using computer-mediated communication in 36 mixed gender (visually cued category) and nationality (non-visually

  7. Social distance and anonymity modulate fairness consideration: An ERP study

    Science.gov (United States)

    Yu, Rongjun; Hu, Pan; Zhang, Ping

    2015-01-01

    Previous research indicated that fairness consideration can be influenced by social distance. However, it is not clear whether social distance and anonymity have an interactive impact on fairness evaluation during asset distribution and whether these processes can be documented in brain activity. Using a modified ultimatum game combined with measures of event related potential (ERP), we examined how social distance and anonymity modulate brain response to inequality. At the behavior level, we found that acceptance rate and reaction time can be substantially modified by social distance and anonymity. Feedback-related negativity, an ERP component associated with conflict between cognitive and emotion motives, was more negative in response to unfairness than fairness from strangers; however, it showed an opposite trend for unfair offers provided by friends, suggesting that the influence of social distance on fairness perception is relatively fast. The P300 in response to fair offers was more positive when the proposers made offers when uncertain about partner identity than when certain about partner identity. These results suggest that unfairness is evaluated in a fast conflict detection stage and a slower stage that integrates more complex social contextual factors such as anonymity. PMID:26293456

  8. An Analysis of College Students' Anonymous Questions about Human Sexuality.

    Science.gov (United States)

    Valois, Robert F.; Waring, Kathryn A.

    1991-01-01

    Study analyzed the frequency and type of questions about sexuality submitted anonymously by college students in health education courses over five semesters. The most common categories were sexual arousal/response; general anatomy/physiology; contraception; dating/relationships; pregnancy/fertility; and sexually transmitted diseases. The appendix…

  9. "Un-Googling” publications: The ethics and problems of anonymization

    DEFF Research Database (Denmark)

    Shklovski, Irina; Vertesi, Janet

    2013-01-01

    to the ethics of exposure of our research participants. We present one approach to anonymization of research results with search engines in mind, which we call un-Googling, that we have developed to minimize risk to our participants. We discuss the considerations that this approach raises and pose a challenge...

  10. Anonymous pastoral care for problems pertaining to sexuality

    NARCIS (Netherlands)

    van Drie, A.; Ganzevoort, R.R.; Spiering, M.

    2014-01-01

    Anonymous pastoral care is one of the options for help in problems pertaining to sexuality. This paper explores the topics they seek help for, the religious aspects involved, and the relation between the normativity of their church tradition on the one hand and sexual and spiritual health criteria

  11. Real-time PCR quantification of arbuscular mycorrhizal fungi: does the use of nuclear or mitochondrial markers make a difference?

    Czech Academy of Sciences Publication Activity Database

    Voříšková, A.; Jansa, J.; Püschel, D.; Krüger, Manuela; Cajthaml, T.; Vosátka, M.; Janoušková, M.

    2017-01-01

    Roč. 27, č. 6 (2017), s. 577-585 ISSN 0940-6360 Institutional support: RVO:61389030 Keywords : Arbuscular mycorrhizal fungi * Isolate discrimination * Microsymbiont screening * Mitochondrial DNA * Molecular genetic quantification * Nuclear ribosomal DNA * plfa * Real-time PCR Subject RIV: EA - Cell Biology OBOR OECD: Cell biology Impact factor: 3.047, year: 2016

  12. Post-Messinian evolutionary relationships across the Sicilian channel: Mitochondrial and nuclear markers link a new green toad from Sicily to African relatives

    Directory of Open Access Journals (Sweden)

    Lo Brutto Sabrina

    2008-02-01

    Full Text Available Abstract Background Little attention has been paid to the consequences of the last landbridge between Africa and Sicily on Mediterranean biogeography. Previous paleontological and scarce molecular data suggest possible faunal exchange later than the well-documented landbridge in the Messinian (5.3 My; however, a possible African origin of recent terrestrial Sicilian fauna has not been thoroughly tested with molecular methods. To gain insight into the phylogeography of the region, we examine two mitochondrial and two nuclear markers (one is a newly adapted intron marker in green toads (Bufo viridis subgroup across that sea barrier, the Strait of Sicily. Results Extensive sampling throughout the western Mediterranean and North Africa revealed a deep sister relationship between Sicilian (Bufo siculus n.sp. and African green toads (B. boulengeri on the mitochondrial and nuclear level. Divergence times estimated under a Bayesian-coalescence framework (mtDNA control region and 16S rRNA range from the Middle Pliocene (3.6 My to Pleistocene (0.16 My with an average (1.83 to 2.0 My around the Pliocene/Pleistocene boundary, suggesting possible land connections younger than the Messinian (5.3 My. We describe green toads from Sicily and some surrounding islands as a new endemic species (Bufo siculus. Bufo balearicus occurs on some western Mediterranean islands (Corsica, Sardinia, Mallorca, and Menorca and the Apennine Peninsula, and is well differentiated on the mitochondrial and nuclear level from B. siculus as well as from B. viridis (Laurenti, whose haplotype group reaches northeastern Italy, north of the Po River. Detection of Calabrian B. balearicus haplotypes in northeastern Sicily suggests recent invasion. Our data agree with paleogeographic and fossil data, which suggest long Plio-Pleistocene isolation of Sicily and episodic Pleistocene faunal exchange across the Strait of Messina. It remains unknown whether both species (B. balearicus, B. siculus

  13. Privacy preserving data anonymization of spontaneous ADE reporting system dataset.

    Science.gov (United States)

    Lin, Wen-Yang; Yang, Duen-Chuan; Wang, Jie-Teng

    2016-07-18

    To facilitate long-term safety surveillance of marketing drugs, many spontaneously reporting systems (SRSs) of ADR events have been established world-wide. Since the data collected by SRSs contain sensitive personal health information that should be protected to prevent the identification of individuals, it procures the issue of privacy preserving data publishing (PPDP), that is, how to sanitize (anonymize) raw data before publishing. Although much work has been done on PPDP, very few studies have focused on protecting privacy of SRS data and none of the anonymization methods is favorable for SRS datasets, due to which contain some characteristics such as rare events, multiple individual records, and multi-valued sensitive attributes. We propose a new privacy model called MS(k, θ (*) )-bounding for protecting published spontaneous ADE reporting data from privacy attacks. Our model has the flexibility of varying privacy thresholds, i.e., θ (*) , for different sensitive values and takes the characteristics of SRS data into consideration. We also propose an anonymization algorithm for sanitizing the raw data to meet the requirements specified through the proposed model. Our algorithm adopts a greedy-based clustering strategy to group the records into clusters, conforming to an innovative anonymization metric aiming to minimize the privacy risk as well as maintain the data utility for ADR detection. Empirical study was conducted using FAERS dataset from 2004Q1 to 2011Q4. We compared our model with four prevailing methods, including k-anonymity, (X, Y)-anonymity, Multi-sensitive l-diversity, and (α, k)-anonymity, evaluated via two measures, Danger Ratio (DR) and Information Loss (IL), and considered three different scenarios of threshold setting for θ (*) , including uniform setting, level-wise setting and frequency-based setting. We also conducted experiments to inspect the impact of anonymized data on the strengths of discovered ADR signals. With all three

  14. Genetic diversity and population genetic analysis of Donax vittatus (Mollusca: Bivalvia) and phylogeny of the genus with mitochondrial and nuclear markers

    Science.gov (United States)

    Fernández-Pérez, Jenyfer; Froufe, Elsa; Nantón, Ana; Gaspar, Miguel B.; Méndez, Josefina

    2017-10-01

    In this study, the genetic diversity of Donax vittatus across the Iberian Peninsula was investigated using four mitochondrial (COI, Cytb, 16S F and M types) and three nuclear (H3, 18S and 28S) genes. These same molecular markers were also sequenced in D. semistriatus and D variegatus to address the phylogenetic relationships of the species of the genus Donax common along the European coasts. Our results showed high haplotype diversity in combination with a low nucleotide diversity and a star-shaped network with a predominant haplotype, indicating a recent population expansion for the examined sampling sites of D. vittatus. Furthermore, analyses of population differentiation performed with COI mitochondrial marker, including global FST estimation and pairwise FST values, indicated the non-existence of significant genetic structure in D. vittatus of Northwest Iberian populations. Because these localities show a high genetic similarity, we suggest that D. vittatus could be a potentially alternative exploitable resource, as complement to the D. trunculus fisheries, whose natural stocks have decreased dramatically in some areas. Furthermore, we present for the first time, evidence of DUI in the clams D. vittatus and D. semistriatus.

  15. Efficient Asymmetric Index Encapsulation Scheme for Anonymous Content Centric Networking

    Directory of Open Access Journals (Sweden)

    Rong Ma

    2017-01-01

    Full Text Available Content Centric Networking (CCN is an effective communication paradigm that well matches the features of wireless environments. To be considered a viable candidate in the emerging wireless networks, despite the clear benefits of location-independent security, CCN must at least have parity with existing solutions for confidential and anonymous communication. This paper designs a new cryptographic scheme, called Asymmetric Index Encapsulation (AIE, that enables the router to test whether an encapsulated header matches the token without learning anything else about both of them. We suggest using the AIE as the core protocol of anonymous Content Centric Networking. A construction of AIE which strikes a balance between efficiency and security is given. The scheme is proved to be secure based on the DBDH assumption in the random oracle with tight reduction, while the encapsulated header and the token in our system consist of only three elements.

  16. Doctor Anonymous: Creating Contexts for Homosexuality as Mental Illness.

    Science.gov (United States)

    Glass, Guy Fredrick

    2018-03-01

    In this essay, the author describes how he faced institutionalized homophobia during his psychiatric training, and how he later wrote a play inspired by the life of a gay psychiatrist. Despite Freud's supportive stance, homosexuality aroused the antipathy of American organized psychiatry and psychoanalysis and came to be listed as an illness in the Diagnostic and Statistical Manual (DSM). Dr. John E. Fryer outed himself as "Dr. H Anonymous" at a 1972 meeting of the American Psychiatric Association, and the next year homosexuality was removed from the DSM. The 2014 play Doctor Anonymous offers a fictionalized account of this watershed moment in the history of the gay rights movement. The author discusses his own psychotherapeutic work with gay male patients, including those who had previously been treated with conversion therapy, and explores how the play mirrors his own life experience and the experience of his patients.

  17. Anonymous voting for multi-dimensional CV quantum system

    International Nuclear Information System (INIS)

    Shi Rong-Hua; Xiao Yi; Shi Jin-Jing; Guo Ying; Lee, Moon-Ho

    2016-01-01

    We investigate the design of anonymous voting protocols, CV-based binary-valued ballot and CV-based multi-valued ballot with continuous variables (CV) in a multi-dimensional quantum cryptosystem to ensure the security of voting procedure and data privacy. The quantum entangled states are employed in the continuous variable quantum system to carry the voting information and assist information transmission, which takes the advantage of the GHZ-like states in terms of improving the utilization of quantum states by decreasing the number of required quantum states. It provides a potential approach to achieve the efficient quantum anonymous voting with high transmission security, especially in large-scale votes. (paper)

  18. A Secure Mobility Network Authentication Scheme Ensuring User Anonymity

    Directory of Open Access Journals (Sweden)

    Ya-Fen Chang

    2017-12-01

    Full Text Available With the rapid growth of network technologies, users are used to accessing various services with their mobile devices. To ensure security and privacy in mobility networks, proper mechanisms to authenticate the mobile user are essential. In this paper, a mobility network authentication scheme based on elliptic curve cryptography is proposed. In the proposed scheme, a mobile user can be authenticated without revealing who he is for user anonymity, and a session key is also negotiated to protect the following communications. The proposed mobility network authentication scheme is analyzed to show that it can ensure security, user anonymity, and convenience. Moreover, Burrows-Abadi-Needham logic (BAN logic is used to deduce the completeness of the proposed authentication scheme.

  19. Concordance of nuclear and mitochondrial DNA markers in detecting a founder event in Lake Clark sockeye salmon

    Science.gov (United States)

    Ramstad, Kristina M.; Woody, Carol Ann; Habicht, Chris; Sage, G. Kevin; Seeb, James E.; Allendorf, Fred W.

    2007-01-01

    Genetic bottleneck effects can reduce genetic variation, persistence probability, and evolutionary potential of populations. Previous microsatellite analysis suggested a bottleneck associated with a common founding of sock-eye salmon Oncorhynchus nerka populations of Lake Clark, Alaska, about 100 to 400 generations ago. The common foundingevent occurred after the last glacial recession and resulted in reduced allelic diversity and strong divergence of Lake Clarksockeye salmon relative to neighboring Six Mile Lake and LakeIliamna populations. Here we used two additional genetic marker types (allozymes and mtDNA) to examine these patterns further. Allozyme and mtDNA results were congruent with the microsatellite data in suggesting a common founder event in LakeClark sockeye salmon and confirmed the divergence of Lake Clarkpopulations from neighboring Six Mile Lake and Lake Iliamna populations. The use of multiple marker types provided better understanding of the bottleneck in Lake Clark. For example, the Sucker Bay Lake population had an exceptionally severe reduction in allelic diversity at microsatellite loci, but not at mtDNA. This suggests that the reduced microsatellite variation in Sucker Bay Lake fish is due to consistently smaller effective population size than other Lake Clark populations, rather than a more acute or additional bottleneck since founding. Caution is urged in using reduced heterozygosity as a measure of genetic bottleneck effects because stochastic variance among loci resulted in an overall increase in allozyme heterozygosity within bottlenecked Lake Clark populations. However, heterozygosity excess, which assesses heterozygosity relative to allelic variation, detected genetic bottleneck effects in both allozyme and microsatellite loci. 

  20. Anonymity communication VPN and Tor: a comparative study

    Science.gov (United States)

    Ramadhani, E.

    2018-03-01

    VPN and Tor is a technology based on anonymity communication. These two technologies have their advantage and disadvantage. The objective of this paper is to find the difference between VPN and Tor technologies by comparing their security of communication on the public network based on the CIA triad concept. The comparative study in this paper is based on the survey method. At last, the result of this paper is a recommendation on when to use a VPN and Tor to secure communication

  1. Can anonymous posters on medical forums be reidentified?

    Science.gov (United States)

    Bobicev, Victoria; Sokolova, Marina; El Emam, Khaled; Jafer, Yasser; Dewar, Brian; Jonker, Elizabeth; Matwin, Stan

    2013-10-03

    Participants in medical forums often reveal personal health information about themselves in their online postings. To feel comfortable revealing sensitive personal health information, some participants may hide their identity by posting anonymously. They can do this by using fake identities, nicknames, or pseudonyms that cannot readily be traced back to them. However, individual writing styles have unique features and it may be possible to determine the true identity of an anonymous user through author attribution analysis. Although there has been previous work on the authorship attribution problem, there has been a dearth of research on automated authorship attribution on medical forums. The focus of the paper is to demonstrate that character-based author attribution works better than word-based methods in medical forums. The goal was to build a system that accurately attributes authorship of messages posted on medical forums. The Authorship Attributor system uses text analysis techniques to crawl medical forums and automatically correlate messages written by the same authors. Authorship Attributor processes unstructured texts regardless of the document type, context, and content. The messages were labeled by nicknames of the forum participants. We evaluated the system's performance through its accuracy on 6000 messages gathered from 2 medical forums on an in vitro fertilization (IVF) support website. Given 2 lists of candidate authors (30 and 50 candidates, respectively), we obtained an F score accuracy in detecting authors of 75% to 80% on messages containing 100 to 150 words on average, and 97.9% on longer messages containing at least 300 words. Authorship can be successfully detected in short free-form messages posted on medical forums. This raises a concern about the meaningfulness of anonymous posting on such medical forums. Authorship attribution tools can be used to warn consumers wishing to post anonymously about the likelihood of their identity being

  2. Gamblers Anonymous as a Recovery Pathway: A Scoping Review

    OpenAIRE

    Schuler, Andr?e; Ferentzy, Peter; Turner, Nigel E.; Skinner, Wayne; McIsaac, Kathryn E.; Ziegler, Carolyn P.; Matheson, Flora I.

    2016-01-01

    Given the preponderance of Gamblers Anonymous (GA), there has been relatively little effort to explore the existing evidence base on its effectiveness as a recovery approach for problem gambling. To remedy this gap in the literature we conducted a scoping review of the literature on mutual aid for individuals experiencing problem gambling published between 2002 and 2015. We searched 13 databases and reviewed reference lists and websites of relevant organizations. We reviewed records for eligi...

  3. Forensic linguistics: Applications of forensic linguistics methods to anonymous letters

    OpenAIRE

    NOVÁKOVÁ, Veronika

    2011-01-01

    The title of my bachelor work is ?Forensic linguistics: Applications of forensic linguistics methods to anonymous letters?. Forensic linguistics is young and not very known branch of applied linguistics. This bachelor work wants to introduce forensic linguistics and its method. The bachelor work has two parts ? theory and practice. The theoretical part informs about forensic linguistics in general. Its two basic aspects utilized in forensic science and respective methods. The practical part t...

  4. Nuclear markers support the mitochondrial phylogeny of Vipera ursinii-renardi complex (Squamata: Viperidae) and species status for the Greek meadow viper.

    Science.gov (United States)

    Mizsei, Edvárd; Jablonski, Daniel; Roussos, Stephanos A; Dimaki, Maria; Ioannidis, Yannis; Nilson, Göran; Nagy, Zoltán T

    2017-01-31

    Meadow vipers (Vipera ursinii-renardi complex) are small-bodied snakes that live in either lowland grasslands or montane subalpine-alpine meadows spanning a distribution from France to western China. This complex has previously been the focus of several taxonomic studies which were based mainly on morphological, allozyme or immunological characters and did not clearly resolve the relationships between the various taxa. Recent mitochondrial DNA analyses found unexpected relationships within the complex which had taxonomical consequences for the detected lineages. The most surprising was the basal phylogenetic position of Vipera ursinii graeca, a taxon described almost 30 years ago from the mountains of Greece. We present here new analyses of three nuclear markers (BDNF, NT3, PRLR; a first for studies of meadow and steppe vipers) as well as analyses of newly obtained mitochondrial DNA sequences (CYT B, ND4).Our Bayesian analyses of nuclear sequences are concordant with previous studies of mitochondrial DNA, in that the phylogenetic position of the graeca clade is a clearly distinguished and distinct lineage separated from all other taxa in the complex. These phylogenetic results are also supported by a distinct morphology, ecology and isolated distribution of this unique taxon. Based on several data sets and an integrative species concept we recommend to elevate this taxon to species level: Vipera graeca Nilson & Andrén, 1988 stat. nov.

  5. Enhancing physicians' use of Alcoholics Anonymous: Internet-based training.

    Science.gov (United States)

    Sellers, Brealyn; Galanter, Marc; Dermatis, Helen; Nachbar, Martin

    2005-01-01

    Alcoholics Anonymous is not yet fully employed by the medical community as a means to enhance patient outcome. The purpose of this study was to evaluate visitors' use of an Internet course on Alcoholics Anonymous, and to compare how various disciplines learned about, gained access to and participated in the course. Demographic information was collected from 414 visitors to the course. 64% of the 414 respondents received their last educational degree within the last 10 years, and had an interest in the topic of addiction prior to their accessing the site. 294 (71%) of those who accessed the course completed it, and those who accessed it learned about it from various sources other than print advertisement in professional journals. Within the 230 physician respondents, 143 (62%) were psychiatrists, 82 (78%) of whom learned about the Internet course via professional journal. Given the need for further training among physicians in the use of Alcoholics Anonymous, the Internet can be utilized to make information available to a large number of people. Because it allows the user to access information outside the traditional means, the barriers to its use are minimal, and it has the potential to effectively convey useful clinical information.

  6. k-Degree Anonymity Model for Social Network Data Publishing

    Directory of Open Access Journals (Sweden)

    MACWAN, K. R.

    2017-11-01

    Full Text Available Publicly accessible platform for social networking has gained special attraction because of its easy data sharing. Data generated on such social network is analyzed for various activities like marketing, social psychology, etc. This requires preservation of sensitive attributes before it becomes easily accessible. Simply removing the personal identities of the users before publishing data is not enough to maintain the privacy of the individuals. The structure of the social network data itself reveals much information regarding its users and their connections. To resolve this problem, k-degree anonymous method is adopted. It emphasizes on the modification of the graph to provide at least k number of nodes that contain the same degree. However, this approach is not efficient on a huge amount of social data and the modification of the original data fails to maintain data usefulness. In addition to this, the current anonymization approaches focus on a degree sequence-based graph model which leads to major modification of the graph topological properties. In this paper, we have proposed an improved k-degree anonymity model that retain the social network structural properties and also to provide privacy to the individuals. Utility measurement approach for community based graph model is used to verify the performance of the proposed technique.

  7. All or Nothing: The False Promise of Anonymity

    Directory of Open Access Journals (Sweden)

    Neil Walker

    2017-05-01

    Full Text Available In early 2016, the International Committee of Medical Journal Editors (ICMJE proposed that responsible sharing of de-identified individual-level data be required for clinical trials published in their affiliated journals. There would be a delay in implementing this policy to allow for the necessary informed consents to work their way through ethical review. Meanwhile, some researchers and policy makers have conflated the notions of de-identification and anonymity. The former is a process that seeks to mitigate disclosure risk though careful application of rules and statistical analysis, while the latter is an absolute state. The consequence of confusing the process and the state is profound. Extensions to the ICMJE proposal based on the presumed anonymity of data include: sharing unconsented data; sharing data without managing access, as Open Data; and proposals to sell data. This essay aims to show that anonymity (the state cannot be guaranteed by de-identification (the process, and so these extensions to the ICMJE proposal should be rejected on governance grounds, if no other. This is not as negative a position as it might seem, as other disciplines have been aware of these limitations and concomitant responsibilities for many years. The essay concludes with an example from social science of managed access strategies that could be adopted by the medical field.

  8. Development of Chloroplast and Nuclear DNA Markers for Chinese Oaks (Quercus Subgenus Quercus and Assessment of Their Utility as DNA Barcodes

    Directory of Open Access Journals (Sweden)

    Jia Yang

    2017-05-01

    Full Text Available Chloroplast DNA (cpDNA is frequently used for species demography, evolution, and species discrimination of plants. However, the lack of efficient and universal markers often brings particular challenges for genetic studies across different plant groups. In this study, chloroplast genomes from two closely related species (Quercus rubra and Castanea mollissima in Fagaceae were compared to explore universal cpDNA markers for the Chinese oak species in Quercus subgenus Quercus, a diverse species group without sufficient molecular differentiation. With the comparison, nine and 14 plastid markers were selected as barcoding and phylogeographic candidates for the Chinese oaks. Five (psbA-trnH, matK-trnK, ycf3-trnS, matK, and ycf1 of the nine plastid candidate barcodes, with the addition of newly designed ITS and a single-copy nuclear gene (SAP, were then tested on 35 Chinese oak species employing four different barcoding approaches (genetic distance-, BLAST-, character-, and tree-based methods. The four methods showed different species identification powers with character-based method performing the best. Of the seven barcodes tested, a barcoding gap was absent in all of them across the Chinese oaks, while ITS and psbA-trnH provided the highest species resolution (30.30% with the character- and BLAST-based methods, respectively. The six-marker combination (psbA-trnH + matK-trnK + matK + ycf1 + ITS + SAP showed the best species resolution (84.85% using the character-based method for barcoding the Chinese oaks. The barcoding results provided additional implications for taxonomy of the Chinese oaks in subg. Quercus, basically identifying three major infrageneric clades of the Chinese oaks (corresponding to Groups Quercus, Cerris, and Ilex referenced to previous phylogenetic classification of Quercus. While the morphology-based allocations proposed for the Chinese oaks in subg. Quercus were challenged. A low variation rate of the chloroplast genome, and

  9. Nuclear and mitochondrial DNA markers in traceability of retail beef samples Marcadores de DNA nuclear e mitocondrial para rastreabilidade da carne bovina comercializada

    Directory of Open Access Journals (Sweden)

    Aline S.M. Cesar

    2010-09-01

    Full Text Available Several characteristics are important in a traceability system of animal products, such as age at slaughter, breed composition, besides information of the productive chain. In general, the certification agent records information about the animals and the system which it came from, although cannot guarantee that the slaughtering, meat processing and distribution are error proof. Besides, there is a differential price, at least at the international market, based on sex and breed composition of the animals. Genetic markers allow identification of characteristics controlled in the beef cattle traceability program, as sex and breed composition, in order to correctly identify and appraise the final product for the consumer. The hypothesis of this study was that the majority beef samples retailed in the local market originate from female with a great participation of zebu breeds. Therefore, the objective of this work was to characterize retail beef samples with DNA markers that identify cattle sex and breed composition. Within 10 beef shops localized in Pirassununga, SP, Brazil, 61 samples were collected, all were genotyped as harboring Bos taurus mitochondrial DNA and 18 were positive for the Y chromosome amplification (male. For the marker sat1711b-Msp I the frequency of the allele A was 0.278 and for the marker Lhr-Hha I the frequency of the allele T was 0.417. The results of sat1711b-Msp I and Lhr-Hha I allelic frequencies are suggestive that the proportion of indicus genome compared with the taurine genome in the market meat is smaller than the observed in the Nellore breed. The procedure described in this study identified sex and subspecies characteristics of beef meat samples, with potential application in meat products certification in special as an auxiliary tool in beef cattle traceability programs.Várias características são importantes no sistema de rastreabilidade, como o sexo, a idade, a raça e/ou a composição racial dos animais, al

  10. New Nuclear SNP Markers Unravel the Genetic Structure and Effective Population Size of Albacore Tuna (Thunnus alalunga.

    Directory of Open Access Journals (Sweden)

    Urtzi Laconcha

    Full Text Available In the present study we have investigated the population genetic structure of albacore (Thunnus alalunga, Bonnaterre 1788 and assessed the loss of genetic diversity, likely due to overfishing, of albacore population in the North Atlantic Ocean. For this purpose, 1,331 individuals from 26 worldwide locations were analyzed by genotyping 75 novel nuclear SNPs. Our results indicated the existence of four genetically homogeneous populations delimited within the Mediterranean Sea, the Atlantic Ocean, the Indian Ocean and the Pacific Ocean. Current definition of stocks allows the sustainable management of albacore since no stock includes more than one genetic entity. In addition, short- and long-term effective population sizes were estimated for the North Atlantic Ocean albacore population, and results showed no historical decline for this population. Therefore, the genetic diversity and, consequently, the adaptive potential of this population have not been significantly affected by overfishing.

  11. Nuclear and mitochondrial markers reveal evidence for genetically segregated cryptic speciation in giant Pacific octopuses from Prince William Sound, Alaska

    Science.gov (United States)

    Toussaint, Rebecca K.; Scheel, David; Sage, G.K.; Talbot, S.L.

    2012-01-01

    Multiple species of large octopus are known from the north Pacific waters around Japan, however only one large species is known in the Gulf of Alaska (the giant Pacific octopus, Enteroctopus dofleini). Current taxonomy of E. dofleini is based on geographic and morphological characteristics, although with advances in genetic technology that is changing. Here, we used two mitochondrial genes (cytochrome b and cytochrome oxidase I), three nuclear genes (rhodopsin, octopine dehydrogenase, and paired-box 6), and 18 microsatellite loci for phylogeographic and phylogenetic analyses of octopuses collected from across southcentral and the eastern Aleutian Islands (Dutch Harbor), Alaska. Our results suggest the presence of a cryptic Enteroctopus species that is allied to, but distinguished from E. dofleini in Prince William Sound, Alaska. Existence of an undescribed and previously unrecognized taxon raises important questions about the taxonomy of octopus in southcentral Alaska waters.

  12. Identification of Paramecium bursaria syngens through molecular markers--comparative analysis of three loci in the nuclear and mitochondrial DNA.

    Science.gov (United States)

    Greczek-Stachura, Magdalena; Potekhin, Alexey; Przyboś, Ewa; Rautian, Maria; Skoblo, Inna; Tarcz, Sebastian

    2012-09-01

    This is the first attempt to resolve the phylogenetic relationship between different syngens of Paramecium bursaria and to investigate at a molecular level the intraspecific differentiation of strains originating from very distant geographical locations. Herein we introduce a new collection of five P. bursaria syngens maintained at St Petersburg State University, as the international collection of syngens was lost in the 1960s. To analyze the degree of speciation within Paramecium bursaria, we examined 26 strains belonging to five different syngens from distant and geographically isolated localities using rDNA (ITS1-5.8S-ITS2-5'LSU) fragments, mitochondrial cytochrome c oxidase subunit I (COI), and H4 gene fragments. It was shown that P. bursaria strains of the same syngens cluster together in all three inferred molecular phylogenies. The genetic diversity among the studied P. bursaria strains based on rDNA sequences was rather low. The COI divergence of Paramecium bursaria was also definitely lower than that observed in the Paramecium aurelia complex. The nucleotide sequences of the H4 gene analyzed in the present study indicate the extent of genetic differences between the syngens of Paramecium bursaria. Our study demonstrates the diagnostic value of molecular markers, which are important tools in the identification of Paramecium bursaria syngens. Copyright © 2011 Elsevier GmbH. All rights reserved.

  13. Molecular phylogeny of Candidula (Geomitridae) land snails inferred from mitochondrial and nuclear markers reveals the polyphyly of the genus.

    Science.gov (United States)

    Chueca, Luis J; Gómez-Moliner, Benjamín J; Madeira, María José; Pfenninger, Markus

    2018-01-01

    The genus Candidula (Geomitridae), consisting of 28 species in Western Europe as currently described, has a disjunct distribution in the Iberian Peninsula, Italy, the Balkans, the Aegean Islands, and one species on the Canary Islands. Although the genus is seemingly well defined by characters of the reproductive system, the relationships within the genus are still unclear and some authors have indicated a possible subgeneric division based on the internal morphology of the dart sac. Despite substantial phylogenetic incongruence, we present a well-resolved molecular phylogeny of Candidula based on two mitochondrial genes (COI and 16S rRNA), the nuclear rDNA region (5.8S rNRA + ITS2 + 28S rRNA) and seven additional nuclear DNA regions developed specifically for this genus (60SL13, 60SL17, 60SL7, RPL14, 40SS6, 60SL9, 60SL13a), in total 5595 bp. Six reciprocally monophyletic entities including Candidula species were recovered, grouping into two major clades. The incorporation of additional geomitrid genera allowed us to unequivocally demonstrate the polyphyly of the genus Candidula. One major clade grouped species from southern France and Italy with the widely distributed species C. unifasciata. The second major clade grouped all the species from the Iberian Peninsula, including C. intersecta and C. gigaxii. Candidula ultima from the Canary Islands was recovered as separated lineage within the latter clade and related to African taxa. The six monophyla were defined as six new genera belonging to different tribes within the Helicellinae. Thus, we could show that similar structures of the stimulatory apparatus of the genital system in different taxa do not necessarily indicate a close phylogenetic relationship in the Geomitridae. More genera of the family are needed to clarify their evolutionary relationships, and to fully understand the evolution of the stimulatory apparatus of the genital system within the Geomitridae. Copyright © 2017 Elsevier Inc. All rights

  14. Differential gene flow of mitochondrial and nuclear DNA markers among chromosomal races of Australian morabine grasshoppers (Vandiemenella, viatica species group).

    Science.gov (United States)

    Kawakami, T; Butlin, R K; Adams, M; Saint, K M; Paull, D J; Cooper, S J B

    2007-12-01

    Recent theoretical developments have led to a renewed interest in the potential role of chromosomal rearrangements in speciation. Australian morabine grasshoppers (genus Vandiemenella, viatica species group) provide an excellent study system to test this potential role of chromosomal rearrangements because they show extensive chromosomal variation and formed the basis of a classic chromosomal speciation model. There are three chromosomal races, viatica19, viatica17, and P24(XY), on Kangaroo Island, South Australia, forming five parapatric populations with four putative contact zones among them. We investigate the extent to which chromosomal variation among these populations may be associated with barriers to gene flow. Population genetic and phylogeographical analyses using 15 variable allozyme loci and the elongation factor-1alpha (EF-1alpha) gene indicate that the three races represent genetically distinct taxa. In contrast, analyses of the mitochondrial cytochrome c oxidase subunit I (COI) gene show the presence of three distinctive and geographically localized groups that do not correspond with the distribution of the chromosomal races. These discordant population genetic patterns are likely to result from introgressive hybridization between the chromosomal races and range expansions/contractions. Overall, these results suggest that reduction of nuclear gene flow may be associated with chromosomal variation, or underlying genetic variation linked with chromosomal variation, whereas mitochondrial gene flow appears to be independent of this variation in these morabine grasshoppers. The identification of an intact contact zone between P24(XY) and viatica17 offers considerable potential for further investigation of molecular mechanisms that maintain distinct nuclear genomes among the chromosomal races.

  15. Traveling the Silk Road: A Measurement of a Large Anonymous Online Marketplace

    Science.gov (United States)

    2012-11-28

    Silk Road, an anonymous, international online marketplace that operates as a Tor hidden service and uses Bitcoin as its exchange currency. We gather...analysis of Silk Road, an anonymous, international on- line marketplace that operates as a Tor hidden service and uses Bitcoin as its exchange currency. We...anonymity, Silk Road needs to also preserve payment anonymity. To that effect, Silk Road only supports Bitcoin (BTC, [30]) as a trading currency

  16. Study of the impact of radionuclides discharges from nuclear industry in the northern Cotentin area on the oyster Crassostrea gigas: expression of cellular stress molecular markers

    International Nuclear Information System (INIS)

    Farcy, E.

    2006-11-01

    This thesis explores the potential radiological impact of radionuclide discharges from the nuclear industry on the Pacific oyster, Crassostrea gigas. One of the major goals of this research was to identify markers that could be used to monitor the effects of low-level chronic irradiation. We decided to focalize on the expression of stress-induced genes involved in the regulation of cellular stress, focusing on transcription. First, homology cloning was used to identify four new cDNAs encoding stress markers. Then data collected at various sites enabled to evidence that mRNA levels for each of the genes of interest naturally vary to a significant degree, based on individual differences and seasonal factors. Comparing oysters from exposed sites with those from a reference site located on the Atlantic coast did not suggest any relationship between mRNA levels changes and the oysters exposure to liquid radioactive waste from the A.R.E.V.A. reprocessing plant. In the environment, we found that those radionuclide releases resulted in a very small increase in radioactivity in oysters, especially compared with their natural radioactivity. In the laboratory, by exposing the oysters to higher radionuclide concentrations than those found in the environment, we were able to identify two genes as potential candidates for studying the effects of chronic exposure to low doses of ionizing radiations in the oyster: genes encoding MT and MXR. We confirmed that transcriptional induction of these two genes occurs in response to high doses of acute irradiation. Finally, the comparison between environmental results and the laboratory results underlined the complementarity of these two approaches. In particular, it revealed that seasonal variations in mRNA levels probably have a significant effect on the stress response. (author)

  17. Conserved genetic regions across angiosperms as tools to develop single-copy nuclear markers in gymnosperms: an example using cycads.

    Science.gov (United States)

    Salas-Leiva, Dayana E; Meerow, Alan W; Francisco-Ortega, Javier; Calonje, Michael; Griffith, M Patrick; Stevenson, Dennis W; Nakamura, Kyoko

    2014-07-01

    Several individuals of the Caribbean Zamia clade and other cycad genera were used to identify single-copy nuclear genes for phylogeographic and phylogenetic studies in Cycadales. Two strategies were employed to select target loci: (i) a tblastX search of Arabidopsis conserved ortholog sequence (COS) set and (ii) a tblastX search of Arabidopsis-Populus-Vitis-Oryza Shared Single-Copy genes (APVO SSC) against the EST Zamia databases in GenBank. From the first strategy, 30 loci were selected, and from the second, 16 loci. In both cases, the matching GenBank accessions of Zamia were used as a query for retrieving highly similar sequences from Cycas, Picea, Pinus species or Ginkgo biloba. After retrieving and aligning all the sequences in each locus, intron predictions were completed to assist in primer design. PCR was carried out in three rounds to detect paralogous loci. A total of 29 loci were successfully amplified as a single band of which 20 were likely single-copy loci. These loci showed different diversity and divergence levels. A preliminary screening allowed us to select 8 promising loci (40S, ATG2, BG, GroES, GTP, LiSH, PEX4 and TR) for the Zamia pumila complex and 4 loci (COS26, GroES, GTP and HTS) for all other cycad genera. Published 2014. This article is a U.S. Government work and is in the public domain in the U.S.A.

  18. Seed gene flow and fine-scale structure in a Mediterranean pine ( Pinus pinaster Ait.) using nuclear microsatellite markers.

    Science.gov (United States)

    González-Martínez, C.; Gerber, S.; Cervera, T.; Martínez-Zapater, M.; Gil, L.; Alía, R.

    2002-06-01

    The Mediterranean populations of maritime pine ( Pinus pinaster Ait.) are typically small and have a scattered distribution, being threatened by human activities and forest fires. In the framework of the genetic-resources conservation program of this species, a native multi-age stand located in a Mediterranean area (central Spain) was studied using three highly polymorphic nuclear microsatellites (SSRs). Spatial autocorrelation analysis was conducted using Moran's index in order to detect fine-scale structure in both natural regeneration and mature trees. The spatial pattern of seed flow based on dispersed progeny was studied using a highly reliable subset of parent-offspring matches obtained by means of parentage analysis and simulation-based calculation of statistical confidence. Maritime pine showed a fine-scale structure at the seedling stage. In natural regeneration, the autocorrelograms indicated a patch size of approximately 10 m. The fine-scale structure seems to be produced by a restricted seed gene flow. In fact, there was an excess of parent-offspring matches in a radius of 15 m from the parent trees. Pines with a heavy seed, such as P. pinaster, are expected to have a short dispersal distance, thus producing a fine-scale structure. However, the fine-scale structure did not persist in the mature trees. Within-population genetic structure in Mediterranean pines may be affected by a number of post-dispersal events (e.g. mortality due to the severity of the Mediterranean climate and animal-mediated secondary dispersal during the summer period). Thus, great alteration in the pattern produced by the initial seed rain and differences in genetic structure between tree cohorts are expected.

  19. Quantum election scheme based on anonymous quantum key distribution

    International Nuclear Information System (INIS)

    Zhou Rui-Rui; Yang Li

    2012-01-01

    An unconditionally secure authority-certified anonymous quantum key distribution scheme using conjugate coding is presented, based on which we construct a quantum election scheme without the help of an entanglement state. We show that this election scheme ensures the completeness, soundness, privacy, eligibility, unreusability, fairness, and verifiability of a large-scale election in which the administrator and counter are semi-honest. This election scheme can work even if there exist loss and errors in quantum channels. In addition, any irregularity in this scheme is sensible. (general)

  20. Resisting stigma, embracing solidarity: An ethnographic study of shopaholics anonymous

    Directory of Open Access Journals (Sweden)

    Rachel Demerling

    2011-03-01

    Full Text Available In recent years, an increased interest in the phenomenon of compulsive buying, which is better known as “shopaholism”, has occurred. This behaviour has been conceptualized as being an uncontrollable urge to purchase things which is pleasurable for an individual or relieves their distress and which results in negative consequences for that individual. This article examines the experiences of individuals within a Shopaholics Anonymous group to understand why individuals decide to join a support group and explore the dynamics of interaction among participants and how that shapes the outcome of their addiction.

  1. Business Information Exchange System with Security, Privacy, and Anonymity

    Directory of Open Access Journals (Sweden)

    Sead Muftic

    2016-01-01

    Full Text Available Business Information Exchange is an Internet Secure Portal for secure management, distribution, sharing, and use of business e-mails, documents, and messages. It has three applications supporting three major types of information exchange systems: secure e-mail, secure instant messaging, and secure sharing of business documents. In addition to standard security services for e-mail letters, which are also applied to instant messages and documents, the system provides innovative features of privacy and full anonymity of users and their locations, actions, transactions, and exchanged resources. In this paper we describe design, implementation, and use of the system.

  2. Large Variation in the Ratio of Mitochondrial to Nuclear Mutation Rate across Animals: Implications for Genetic Diversity and the Use of Mitochondrial DNA as a Molecular Marker.

    Science.gov (United States)

    Allio, Remi; Donega, Stefano; Galtier, Nicolas; Nabholz, Benoit

    2017-11-01

    It is commonly assumed that mitochondrial DNA (mtDNA) evolves at a faster rate than nuclear DNA (nuDNA) in animals. This has contributed to the popularity of mtDNA as a molecular marker in evolutionary studies. Analyzing 121 multilocus data sets and four phylogenomic data sets encompassing 4,676 species of animals, we demonstrate that the ratio of mitochondrial over nuclear mutation rate is highly variable among animal taxa. In nonvertebrates, such as insects and arachnids, the ratio of mtDNA over nuDNA mutation rate varies between 2 and 6, whereas it is above 20, on average, in vertebrates such as scaled reptiles and birds. Interestingly, this variation is sufficient to explain the previous report of a similar level of mitochondrial polymorphism, on average, between vertebrates and nonvertebrates, which was originally interpreted as reflecting the effect of pervasive positive selection. Our analysis rather indicates that the among-phyla homogeneity in within-species mtDNA diversity is due to a negative correlation between mtDNA per-generation mutation rate and effective population size, irrespective of the action of natural selection. Finally, we explore the variation in the absolute per-year mutation rate of both mtDNA and nuDNA using a reduced data set for which fossil calibration is available, and discuss the potential determinants of mutation rate variation across genomes and taxa. This study has important implications regarding DNA-based identification methods in predicting that mtDNA barcoding should be less reliable in nonvertebrates than in vertebrates. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  3. Marker development

    Energy Technology Data Exchange (ETDEWEB)

    Adams, M.R.

    1987-05-01

    This report is to discuss the marker development for radioactive waste disposal sites. The markers must be designed to last 10,000 years, and place no undue burdens on the future generations. Barriers cannot be constructed that preclude human intrusion. Design specifications for surface markers will be discussed, also marker pictograms will also be covered.

  4. Efficient expression of nuclear transgenes in the green alga Chlamydomonas: synthesis of an HIV antigen and development of a new selectable marker.

    Science.gov (United States)

    Barahimipour, Rouhollah; Neupert, Juliane; Bock, Ralph

    2016-03-01

    The unicellular green alga Chlamydomonas reinhardtii has become an invaluable model system in plant biology. There is also considerable interest in developing this microalga into an efficient production platform for biofuels, pharmaceuticals, green chemicals and industrial enzymes. However, the production of foreign proteins in the nucleocytosolic compartment of Chlamydomonas is greatly hampered by the inefficiency of transgene expression from the nuclear genome. We have recently addressed this limitation by isolating mutant algal strains that permit high-level transgene expression and by determining the contributions of GC content and codon usage to gene expression efficiency. Here we have applied these new tools and explored the potential of Chlamydomonas to produce a recombinant biopharmaceutical, the HIV antigen P24. We show that a codon-optimized P24 gene variant introduced into our algal expression strains give rise to recombinant protein accumulation levels of up to 0.25% of the total cellular protein. Moreover, in combination with an expression strain, a resynthesized nptII gene becomes a highly efficient selectable marker gene that facilitates the selection of transgenic algal clones at high frequency. By establishing simple principles of successful transgene expression, our data open up new possibilities for biotechnological research in Chlamydomonas.

  5. A New Classification of Ficus Subsection Urostigma (Moraceae Based on Four Nuclear DNA Markers (ITS, ETS, G3pdh, and ncpGS, Morphology and Leaf Anatomy.

    Directory of Open Access Journals (Sweden)

    Bhanumas Chantarasuwan

    Full Text Available Ficus subsection Urostigma as currently circumscribed contains 27 species, distributed in Africa, Asia, Australia and the Pacific, and is of key importance to understand the origin and evolution of Ficus and the fig-wasp mutualism. The species of subsection Urostigma are very variable in morphological characters and exhibit a wide range of often partly overlapping distributions, which makes identification often difficult. The systematic classification within and between this subsection and others is problematic, e.g., it is still unclear where to classify F. amplissima and F. rumphii. To clarify the circumscription of subsection Urostigma, a phylogenetic reconstruction based on four nuclear DNA markers (ITS, ETS, G3pdh, and ncpGS combined with morphology and leaf anatomy is conducted. The phylogenetic tree based on the combined datasets shows that F. madagascariensis, a Madagascan species, is sister to the remainder of subsect. Urostigma. Ficus amplissima and F. rumphii, formerly constituting sect. Leucogyne, appear to be imbedded in subsect. Conosycea. The result of the phylogenetic analysis necessitates nomenclatural adjustments. A new classification of Ficus subsection Urostigma is presented along with the morphological and leaf anatomical apomorphies typical for the clades. Two new species are described ─ one in subsect. Urostigma, the other in Conosycea. One variety is raised to species level.

  6. A New Classification of Ficus Subsection Urostigma (Moraceae) Based on Four Nuclear DNA Markers (ITS, ETS, G3pdh, and ncpGS), Morphology and Leaf Anatomy.

    Science.gov (United States)

    Chantarasuwan, Bhanumas; Berg, Cornelis C; Kjellberg, Finn; Rønsted, Nina; Garcia, Marjorie; Baider, Claudia; van Welzen, Peter C

    2015-01-01

    Ficus subsection Urostigma as currently circumscribed contains 27 species, distributed in Africa, Asia, Australia and the Pacific, and is of key importance to understand the origin and evolution of Ficus and the fig-wasp mutualism. The species of subsection Urostigma are very variable in morphological characters and exhibit a wide range of often partly overlapping distributions, which makes identification often difficult. The systematic classification within and between this subsection and others is problematic, e.g., it is still unclear where to classify F. amplissima and F. rumphii. To clarify the circumscription of subsection Urostigma, a phylogenetic reconstruction based on four nuclear DNA markers (ITS, ETS, G3pdh, and ncpGS) combined with morphology and leaf anatomy is conducted. The phylogenetic tree based on the combined datasets shows that F. madagascariensis, a Madagascan species, is sister to the remainder of subsect. Urostigma. Ficus amplissima and F. rumphii, formerly constituting sect. Leucogyne, appear to be imbedded in subsect. Conosycea. The result of the phylogenetic analysis necessitates nomenclatural adjustments. A new classification of Ficus subsection Urostigma is presented along with the morphological and leaf anatomical apomorphies typical for the clades. Two new species are described ─ one in subsect. Urostigma, the other in Conosycea. One variety is raised to species level.

  7. Admixture, one-source colonization or long-term persistence of maritime pine in the Castilian Plateau? Insights from nuclear micro satellite markers

    Energy Technology Data Exchange (ETDEWEB)

    Lucas, A. I. de; Gonzalez Martinez, S. C.; Hidalgo, E.; Bravo, F.; Heuertz, M.

    2009-07-01

    Atlantic and Mediterranean populations of maritime pine are very different in quantitative and adaptive traits, even to be considered different subspecies. Different authors have suggested the existence of glacial refuge for this species both in Portugal and eastern Spain based on molecular markers and supported by pollen and fossil records. In addition, based on the existence of high levels of haplotypic variation in this region, the Castilian Plateau is suggested as a contact zone between Atlantic and Mediterranean gene pools of the species. This hypothesis is tested using Bayesian clustering methods and exclusion tests based on multi locus genotypes obtained by geno typing 13 populations with three highly polymorphic nuclear micro satellites. The results show that Castilian Plateau populations constitute a different gene pool by itself that can not be fully originated from the Mediterranean or the Atlantic gene pools, or from a mixture of both. Therefore, three different hypotheses have been considered as plausible causes to give rise to Castilian Plateau maritime pine populations: i) fast colonization of the region from one or more Mediterranean refugial areas, ii) existence of cryptic refugia for the species in the zone, and iii) introduction of exotic material by humans. (Author) 55 refs.

  8. On-line high-performance liquid chromatography-ultraviolet-nuclear magnetic resonance method of the markers of nerve agents for verification of the Chemical Weapons Convention.

    Science.gov (United States)

    Mazumder, Avik; Gupta, Hemendra K; Garg, Prabhat; Jain, Rajeev; Dubey, Devendra K

    2009-07-03

    This paper details an on-flow liquid chromatography-ultraviolet-nuclear magnetic resonance (LC-UV-NMR) method for the retrospective detection and identification of alkyl alkylphosphonic acids (AAPAs) and alkylphosphonic acids (APAs), the markers of the toxic nerve agents for verification of the Chemical Weapons Convention (CWC). Initially, the LC-UV-NMR parameters were optimized for benzyl derivatives of the APAs and AAPAs. The optimized parameters include stationary phase C(18), mobile phase methanol:water 78:22 (v/v), UV detection at 268nm and (1)H NMR acquisition conditions. The protocol described herein allowed the detection of analytes through acquisition of high quality NMR spectra from the aqueous solution of the APAs and AAPAs with high concentrations of interfering background chemicals which have been removed by preceding sample preparation. The reported standard deviation for the quantification is related to the UV detector which showed relative standard deviations (RSDs) for quantification within +/-1.1%, while lower limit of detection upto 16mug (in mug absolute) for the NMR detector. Finally the developed LC-UV-NMR method was applied to identify the APAs and AAPAs in real water samples, consequent to solid phase extraction and derivatization. The method is fast (total experiment time approximately 2h), sensitive, rugged and efficient.

  9. Revealing pancrustacean relationships: Phylogenetic analysis of ribosomal protein genes places Collembola (springtails in a monophyletic Hexapoda and reinforces the discrepancy between mitochondrial and nuclear DNA markers

    Directory of Open Access Journals (Sweden)

    Mariën J

    2008-03-01

    Full Text Available Abstract Background In recent years, several new hypotheses on phylogenetic relations among arthropods have been proposed on the basis of DNA sequences. One of the challenged hypotheses is the monophyly of hexapods. This discussion originated from analyses based on mitochondrial DNA datasets that, due to an unusual positioning of Collembola, suggested that the hexapod body plan evolved at least twice. Here, we re-evaluate the position of Collembola using ribosomal protein gene sequences. Results In total 48 ribosomal proteins were obtained for the collembolan Folsomia candida. These 48 sequences were aligned with sequence data on 35 other ecdysozoans. Each ribosomal protein gene was available for 25% to 86% of the taxa. However, the total sequence information was unequally distributed over the taxa and ranged between 4% and 100%. A concatenated dataset was constructed (5034 inferred amino acids in length, of which ~66% of the positions were filled. Phylogenetic tree reconstructions, using Maximum Likelihood, Maximum Parsimony, and Bayesian methods, resulted in a topology that supports monophyly of Hexapoda. Conclusion Although ribosomal proteins in general may not evolve independently, they once more appear highly valuable for phylogenetic reconstruction. Our analyses clearly suggest that Hexapoda is monophyletic. This underpins the inconsistency between nuclear and mitochondrial datasets when analyzing pancrustacean relationships. Caution is needed when applying mitochondrial markers in deep phylogeny.

  10. Does better taxon sampling help? A new phylogenetic hypothesis for Sepsidae (Diptera: Cyclorrhapha) based on 50 new taxa and the same old mitochondrial and nuclear markers.

    Science.gov (United States)

    Zhao, Lei; Annie, Ang Shi Hui; Amrita, Srivathsan; Yi, Su Kathy Feng; Rudolf, Meier

    2013-10-01

    We here present a phylogenetic hypothesis for Sepsidae (Diptera: Cyclorrhapha), a group of schizophoran flies with ca. 320 described species that is widely used in sexual selection research. The hypothesis is based on five nuclear and five mitochondrial markers totaling 8813 bp for ca. 30% of the diversity (105 sepsid taxa) and - depending on analysis - six or nine outgroup species. Maximum parsimony (MP), maximum likelihood (ML), and Bayesian inferences (BI) yield overall congruent, well-resolved, and supported trees that are largely unaffected by three different ways to partition the data in BI and ML analyses. However, there are also five areas of uncertainty that affect suprageneric relationships where different analyses yield alternate topologies and MP and ML trees have significant conflict according to Shimodaira-Hasegawa tests. Two of these were already affected by conflict in a previous analysis that was based on the same genes and a subset of 69 species. The remaining three involve newly added taxa or genera whose relationships were previously resolved with low support. We thus find that the denser taxon sample in the present analysis does not reduce the topological conflict that had been identified previously. The present study nevertheless presents a significant contribution to the understanding of sepsid relationships in that 50 additional taxa from 18 genera are added to the Tree-of-Life of Sepsidae and that the placement of most taxa is well supported and robust to different tree reconstruction techniques. Copyright © 2013 Elsevier Inc. All rights reserved.

  11. Revealing pancrustacean relationships: phylogenetic analysis of ribosomal protein genes places Collembola (springtails) in a monophyletic Hexapoda and reinforces the discrepancy between mitochondrial and nuclear DNA markers.

    Science.gov (United States)

    Timmermans, M J T N; Roelofs, D; Mariën, J; van Straalen, N M

    2008-03-12

    In recent years, several new hypotheses on phylogenetic relations among arthropods have been proposed on the basis of DNA sequences. One of the challenged hypotheses is the monophyly of hexapods. This discussion originated from analyses based on mitochondrial DNA datasets that, due to an unusual positioning of Collembola, suggested that the hexapod body plan evolved at least twice. Here, we re-evaluate the position of Collembola using ribosomal protein gene sequences. In total 48 ribosomal proteins were obtained for the collembolan Folsomia candida. These 48 sequences were aligned with sequence data on 35 other ecdysozoans. Each ribosomal protein gene was available for 25% to 86% of the taxa. However, the total sequence information was unequally distributed over the taxa and ranged between 4% and 100%. A concatenated dataset was constructed (5034 inferred amino acids in length), of which ~66% of the positions were filled. Phylogenetic tree reconstructions, using Maximum Likelihood, Maximum Parsimony, and Bayesian methods, resulted in a topology that supports monophyly of Hexapoda. Although ribosomal proteins in general may not evolve independently, they once more appear highly valuable for phylogenetic reconstruction. Our analyses clearly suggest that Hexapoda is monophyletic. This underpins the inconsistency between nuclear and mitochondrial datasets when analyzing pancrustacean relationships. Caution is needed when applying mitochondrial markers in deep phylogeny.

  12. Nonexposure Accurate Location K-Anonymity Algorithm in LBS

    Directory of Open Access Journals (Sweden)

    Jinying Jia

    2014-01-01

    Full Text Available This paper tackles location privacy protection in current location-based services (LBS where mobile users have to report their exact location information to an LBS provider in order to obtain their desired services. Location cloaking has been proposed and well studied to protect user privacy. It blurs the user’s accurate coordinate and replaces it with a well-shaped cloaked region. However, to obtain such an anonymous spatial region (ASR, nearly all existent cloaking algorithms require knowing the accurate locations of all users. Therefore, location cloaking without exposing the user’s accurate location to any party is urgently needed. In this paper, we present such two nonexposure accurate location cloaking algorithms. They are designed for K-anonymity, and cloaking is performed based on the identifications (IDs of the grid areas which were reported by all the users, instead of directly on their accurate coordinates. Experimental results show that our algorithms are more secure than the existent cloaking algorithms, need not have all the users reporting their locations all the time, and can generate smaller ASR.

  13. Nonexposure accurate location K-anonymity algorithm in LBS.

    Science.gov (United States)

    Jia, Jinying; Zhang, Fengli

    2014-01-01

    This paper tackles location privacy protection in current location-based services (LBS) where mobile users have to report their exact location information to an LBS provider in order to obtain their desired services. Location cloaking has been proposed and well studied to protect user privacy. It blurs the user's accurate coordinate and replaces it with a well-shaped cloaked region. However, to obtain such an anonymous spatial region (ASR), nearly all existent cloaking algorithms require knowing the accurate locations of all users. Therefore, location cloaking without exposing the user's accurate location to any party is urgently needed. In this paper, we present such two nonexposure accurate location cloaking algorithms. They are designed for K-anonymity, and cloaking is performed based on the identifications (IDs) of the grid areas which were reported by all the users, instead of directly on their accurate coordinates. Experimental results show that our algorithms are more secure than the existent cloaking algorithms, need not have all the users reporting their locations all the time, and can generate smaller ASR.

  14. A Remote User Authentication Scheme with Anonymity for Mobile Devices

    Directory of Open Access Journals (Sweden)

    Soobok Shin

    2012-04-01

    Full Text Available With the rapid growth of information technologies, mobile devices have been utilized in a variety of services such as e-commerce. When a remote server provides such e-commerce services to a user, it must verify the legitimacy of the user over an insecure communication channel. Therefore, remote user authentication has been widely deployed to verify the legitimacy of remote user login requests using mobile devices like smart cards. In this paper we propose a smart card-based authentication scheme that provides both user anonymity and mutual authentication between a remote server and a user. The proposed authentication scheme is a simple and efficient system applicable to the limited resource and low computing performance of the smart card. The proposed scheme provides not only resilience to potential attacks in the smart card-based authentication scheme, but also secure authentication functions. A smart card performs a simple one-way hash function, the operations of exclusive-or and concatenation in the authentication phase of the proposed scheme. The proposed scheme also provides user anonymity using a dynamic identity and key agreement, and secure password change.

  15. Keeping mum about dad: "contracts" to protect gamete donor anonymity.

    Science.gov (United States)

    Rees, Anne

    2012-06-01

    This article considers the legal status of so-called contracts for anonymity between fertility clinics and donors of gametes that were made in the period before legislation authorising disclosure. It notes that while clinics frequently cite the existence of these "contracts" to argue against retrospective legislation authorising disclosure of the donor's identity, they may be nothing more than one-sided statements of informed consent. However, the article notes that even if an agreement between a donor and a clinic is not contractual, it does not follow that a person conceived through assisted reproductive technology has any right of access to the identity of the donor. The writer has not been able to locate examples of written promises by the clinics promising anonymity. There are written promises by the donors not to seek the identity of the recipients. These promises do not bind the resulting offspring nor do they appear to be supported by consideration. The article suggests that the basis for any individual donor to restrain a clinic from revealing their identity may be found in promissory estoppel. Nevertheless, there is no real issue in Australia concerning clinics revealing these details absent legislative authority. The issue is whether parliaments will legislate to authorise the disclosure. The article notes that it would be rare for parliaments to legislate to overturn existing legal contracts but suggests that the contract argument may not be as strong as has been thought.

  16. Parameterized Complexity of k-Anonymity: Hardness and Tractability

    Science.gov (United States)

    Bonizzoni, Paola; Della Vedova, Gianluca; Dondi, Riccardo; Pirola, Yuri

    The problem of publishing personal data without giving up privacy is becoming increasingly important. A precise formalization that has been recently proposed is the k-anonymity, where the rows of a table are partitioned in clusters of size at least k and all rows in a cluster become the same tuple after the suppression of some entries. The natural optimization problem, where the goal is to minimize the number of suppressed entries, is hard even when the stored values are over a binary alphabet or the table consists of a bounded number of columns. In this paper we study how the complexity of the problem is influenced by different parameters. First we show that the problem is W[1]-hard when parameterized by the value of the solution (and k). Then we exhibit a fixed-parameter algorithm when the problem is parameterized by the number of columns and the number of different values in any column.

  17. Cloud Based Data Protection in Anonymously Controlled SDN

    Directory of Open Access Journals (Sweden)

    Jian Shen

    2018-01-01

    Full Text Available Nowadays, Software Defined Network (SDN develops rapidly for its novel structure which separates the control plane and the data plane of network devices. Many researchers devoted themselves to the study of such a special network. However, some limitations restrict the development of SDN. On the one hand, the single controller in the conventional model bears all threats, and the corruption of it will result in network paralysis. On the other hand, the data will be increasing more in SDN switches in the data plane, while the storage space of these switches is limited. In order to solve the mentioned issues, we propose two corresponding protocols in this paper. Specifically, one is an anonymous protocol in the control plane, and the other is a verifiable outsourcing protocol in the data plane. The evaluation indicates that our protocol is correct, secure, and efficient.

  18. A machine learning methodology for medical imaging anonymization.

    Science.gov (United States)

    Monteiro, Eriksson; Costa, Carlos; Oliveira, Jose Luis

    2015-08-01

    Privacy protection is a major requirement for the complete success of EHR systems, becoming even more critical in collaborative scenarios, where data is shared among institutions and practitioners. While textual data can be easily de-identified, patient data in medical images implies a more elaborate approach. In this work we present a solution for sensitive word identification in medical images based on a combination of two machine-learning models, achieving a F1-score of 0.94. Three experts evaluated the system performance. They analyzed the output of the present methodology and categorized the studies in three groups: studies that had their sensitive words removed (true positive), studies with complete patient identity (false negative) and studies with mistakenly removed data (false positive). The experts were unanimous regarding the relevance of the present tool in collaborative medical environments, as it may improve the exchange of anonymized patient data between institutions.

  19. Father-daughter incest: data from an anonymous computerized survey.

    Science.gov (United States)

    Stroebel, Sandra S; O'Keefe, Stephen L; Beard, Keith W; Kuo, Shih-Ya; Swindell, Samuel V S; Kommor, Martin J

    2012-01-01

    Retrospective data were entered anonymously by 1,521 adult women using computer-assisted self-interview. Nineteen were classified as victims of father-daughter incest, and 241 were classified as victims of sexual abuse by an adult other than their father before reaching 18 years of age. The remaining 1,261 served as controls. Incest victims were more likely than controls to endorse feeling damaged, psychologically injured, estranged from one or both parents, and shamed by others when they tried to open up about their experience. They had been eroticized early on by the incest experience, and it interfered with their adult sexuality. Incest victims experienced coitus earlier than controls and after reaching age 18 had more sex partners and were more likely to have casual sex outside their primary relationship and engage in sex for money than controls. They also had worse scores on scales measuring depression, sexual satisfaction, and communication about sex than controls.

  20. Anonymization of Electronic Medical Records to Support Clinical Analysis

    CERN Document Server

    Gkoulalas-Divanis, Aris

    2013-01-01

    Anonymization of Electronic Medical Records to Support Clinical Analysis closely examines the privacy threats that may arise from medical data sharing, and surveys the state-of-the-art methods developed to safeguard data against these threats. To motivate the need for computational methods, the book first explores the main challenges facing the privacy-protection of medical data using the existing policies, practices and regulations. Then, it takes an in-depth look at the popular computational privacy-preserving methods that have been developed for demographic, clinical and genomic data sharing, and closely analyzes the privacy principles behind these methods, as well as the optimization and algorithmic strategies that they employ. Finally, through a series of in-depth case studies that highlight data from the US Census as well as the Vanderbilt University Medical Center, the book outlines a new, innovative class of privacy-preserving methods designed to ensure the integrity of transferred medical data for su...

  1. Anonymity versus privacy: selective information sharing in online cancer communities.

    Science.gov (United States)

    Frost, Jeana; Vermeulen, Ivar E; Beekers, Nienke

    2014-05-14

    Active sharing in online cancer communities benefits patients. However, many patients refrain from sharing health information online due to privacy concerns. Existing research on privacy emphasizes data security and confidentiality, largely focusing on electronic medical records. Patient preferences around information sharing in online communities remain poorly understood. Consistent with the privacy calculus perspective adopted from e-commerce research, we suggest that patients approach online information sharing instrumentally, weighing privacy costs against participation benefits when deciding whether to share certain information. Consequently, we argue that patients prefer sharing clinical information over daily life and identity information that potentially compromises anonymity. Furthermore, we explore whether patients' prior experiences, age, health, and gender affect perceived privacy costs and thus willingness to share information. The goal of the present study is to document patient preferences for sharing information within online health platforms. A total of 115 cancer patients reported sharing intentions for 15 different types of information, demographics, health status, prior privacy experiences, expected community utility, and privacy concerns. Factor analysis on the 15 information types revealed 3 factors coinciding with 3 proposed information categories: clinical, daily life, and identity information. A within-subject ANOVA showed a strong preference for sharing clinical information compared to daily life and identity information (F1,114=135.59, P=.001, η(2)=.93). Also, adverse online privacy experiences, age, and health status negatively affected information-sharing intentions. Female patients shared information less willingly. Respondents' information-sharing intentions depend on dispositional and situational factors. Patients share medical details more willingly than daily life or identity information. The results suggest the need to focus on

  2. Anonymity Versus Privacy: Selective Information Sharing in Online Cancer Communities

    Science.gov (United States)

    Vermeulen, Ivar E; Beekers, Nienke

    2014-01-01

    Background Active sharing in online cancer communities benefits patients. However, many patients refrain from sharing health information online due to privacy concerns. Existing research on privacy emphasizes data security and confidentiality, largely focusing on electronic medical records. Patient preferences around information sharing in online communities remain poorly understood. Consistent with the privacy calculus perspective adopted from e-commerce research, we suggest that patients approach online information sharing instrumentally, weighing privacy costs against participation benefits when deciding whether to share certain information. Consequently, we argue that patients prefer sharing clinical information over daily life and identity information that potentially compromises anonymity. Furthermore, we explore whether patients’ prior experiences, age, health, and gender affect perceived privacy costs and thus willingness to share information. Objective The goal of the present study is to document patient preferences for sharing information within online health platforms. Methods A total of 115 cancer patients reported sharing intentions for 15 different types of information, demographics, health status, prior privacy experiences, expected community utility, and privacy concerns. Results Factor analysis on the 15 information types revealed 3 factors coinciding with 3 proposed information categories: clinical, daily life, and identity information. A within-subject ANOVA showed a strong preference for sharing clinical information compared to daily life and identity information (F 1,114=135.59, P=.001, η2=.93). Also, adverse online privacy experiences, age, and health status negatively affected information-sharing intentions. Female patients shared information less willingly. Conclusions Respondents’ information-sharing intentions depend on dispositional and situational factors. Patients share medical details more willingly than daily life or identity

  3. The Pattern of Drug Abuse in Anonymous Adidcts

    Directory of Open Access Journals (Sweden)

    Seyede Maryam Vahdat-Shariat-Panahi

    2010-04-01

    Full Text Available Objective: Having the information about pattern of substance abuse in the community and its epidemiological features is one of the most important protocols for evaluation, follow–up and control of the use of these substances. The aim of this study was to evaluate the patterns of substances abuse among narcotic anonymous (N. A. addicted patients. Materials & Methods: In this descriptive and analytical study, three hundred patients from narcotic abusers anonymous (N. A. association who were referred to a treatment center in Tehran were participated consecutively. The information about demographic characteristics, socioeconomic status, type of drug and the patterns of substance abuse of all cases were collected by researcher made questionnaire. Data were analyzed by Chi–Square test. Results: 80% of the patients were male. Almost 65. 2% of cases aged less than 40 years. More than two–third of cases had free jobs and 21. 2% of them were unemployed. Also, 32% of patients had college degrees. The most common types of abused substance were opium (88%, cigarette (76.7%, and alcohol (63% and 34% of them used substances intravenously. The use of alcohol (P=0.033, cannabis (P<0.001, cocaine (P=0.009 and ecstasy (P<0.001 was more prevalent significantly in the cases less than 40 years old than the elderly. Conclusion: It seems that the trend of substance abuse has been changed to younger population. The pattern of drug abuse in young adults is more toward psychosis drugs such as cocaine and ecstasy.

  4. Unison as a Self-Stabilizing Wave Stream Algorithm in Asynchronous Anonymous Networks

    OpenAIRE

    Boulinier, Christian

    2007-01-01

    Rapport de recherche.; How to pass from local to global scales in anonymous networks? How to organize a selfstabilizing propagation of information with feedback. From the Angluin impossibility results, we cannot elect a leader in a general anonymous network. Thus, it is impossible to build a rooted spanning tree. Many problems can only be solved by probabilistic methods. In this paper we show how to use Unison to design a self-stabilizing barrier synchronization in an anonymous network. We sh...

  5. Enhanced P-Sensitive K-Anonymity Models for Privacy Preserving Data Publishing

    OpenAIRE

    Xiaoxun Sun; Hua Wang; Jiuyong Li; Traian Marius Truta

    2008-01-01

    Publishing data for analysis from a micro data table containing sensitive attributes, while maintaining individual privacy, is a problem of increasing significance today. The k-anonymity model was proposed for privacy preserving data publication. While focusing on identity disclosure, k-anonymity model fails to protect attribute disclosure to some extent. Many efforts are made to enhance the k-anonymity model recently. In this paper, we propose two new privacy protection models called (p, a)-...

  6. Attribute Utility Motivated k-anonymization of Datasets to Support the Heterogeneous Needs of Biomedical Researchers

    OpenAIRE

    Ye, Huimin; Chen, Elizabeth S.

    2011-01-01

    In order to support the increasing need to share electronic health data for research purposes, various methods have been proposed for privacy preservation including k-anonymity. Many k-anonymity models provide the same level of anoymization regardless of practical need, which may decrease the utility of the dataset for a particular research study. In this study, we explore extensions to the k-anonymity algorithm that aim to satisfy the heterogeneous needs of different researchers while preser...

  7. Shoplifting and eating disorders: an anonymous self-administered survey.

    Science.gov (United States)

    Yanase, Maya; Sugihara, Genichi; Murai, Toshiya; Noma, Shun'ichi

    2017-04-28

    To explore the characteristics of eating disorders related to shoplifting behavior and identify the risk and protective factors related to shoplifting among patients with eating disorders. Eighty females with eating disorders were recruited from an eating disorders clinic. They were asked to complete anonymous self-report questionnaires on demographic characteristics, shoplifting behavior, psychological characteristics and eating disorder symptomology. We investigated differences in clinical characteristics between those with and without shoplifting history or a current drive to shoplift. The response rate was 92.5%. Of the respondents, 37.8% reported a history of shoplifting and 16.2% a current drive for shoplifting. The patients with shoplifting history had lower socioeconomic status (SES), higher impulsivity and higher symptom severity of eating disorders compared with those without this history. The patients with a current drive for shoplifting had more depressive symptoms, more severe anxiety, more obsessional traits, and higher symptom severity of eating disorders. Severity of illness and SES seem to have a serious impact on shoplifting behavior among eating disordered patients. These findings may suggest risk and protective factors related to shoplifting among eating disordered patients.

  8. 'Gift without a price tag': altruism in anonymous semen donation.

    Science.gov (United States)

    Yee, Samantha

    2009-01-01

    Commercialization of human gametes is now legally prohibited in Canada under the Assisted Human Reproduction Act 2004, making semen donation in Canada altruistic and anonymous by law. Donors must be altruistically motivated to donate gametes without receiving monetary rewards. Globally speaking, Canada is neither the first nor the only country in the world that has legislation to support altruistic gamete donation. Other countries have advocated similar systems either through legislative changes or implementation of best practice models. This paper is a review of literature assessing the differences in donation behaviours under paid and altruistic donation models. It provides contextual information of the current semen donation situation in Canada, while drawing upon relevant literature and research data from other countries as references. The author also attempts to re-conceptualize the meanings of altruism through exploring the complex interplay between psycho-social and institutional factors in influencing donors' behaviours. Although there is a substantial amount of research studying the impacts on donor recruitment when payment is withdrawn, very few research studies are found that focus on exploring altruistic donor recruitment strategies. It is unrealistic to expect the altruistic donation culture to emerge spontaneously in Canada without any multi-level efforts to coordinate the recruitment strategies. Research programmes are greatly needed to generate empirical knowledge that can guide the development of altruistic donor recruitment models geared to the current socio-cultural environment and legislative framework in Canada. The findings will be invaluable when the legislation comes up for parliamentary review in the near future.

  9. iDASH: integrating data for analysis, anonymization, and sharing

    Science.gov (United States)

    Bafna, Vineet; Boxwala, Aziz A; Chapman, Brian E; Chapman, Wendy W; Chaudhuri, Kamalika; Day, Michele E; Farcas, Claudiu; Heintzman, Nathaniel D; Jiang, Xiaoqian; Kim, Hyeoneui; Kim, Jihoon; Matheny, Michael E; Resnic, Frederic S; Vinterbo, Staal A

    2011-01-01

    iDASH (integrating data for analysis, anonymization, and sharing) is the newest National Center for Biomedical Computing funded by the NIH. It focuses on algorithms and tools for sharing data in a privacy-preserving manner. Foundational privacy technology research performed within iDASH is coupled with innovative engineering for collaborative tool development and data-sharing capabilities in a private Health Insurance Portability and Accountability Act (HIPAA)-certified cloud. Driving Biological Projects, which span different biological levels (from molecules to individuals to populations) and focus on various health conditions, help guide research and development within this Center. Furthermore, training and dissemination efforts connect the Center with its stakeholders and educate data owners and data consumers on how to share and use clinical and biological data. Through these various mechanisms, iDASH implements its goal of providing biomedical and behavioral researchers with access to data, software, and a high-performance computing environment, thus enabling them to generate and test new hypotheses. PMID:22081224

  10. Gamblers Anonymous as a Recovery Pathway: A Scoping Review.

    Science.gov (United States)

    Schuler, Andrée; Ferentzy, Peter; Turner, Nigel E; Skinner, Wayne; McIsaac, Kathryn E; Ziegler, Carolyn P; Matheson, Flora I

    2016-12-01

    Given the preponderance of Gamblers Anonymous (GA), there has been relatively little effort to explore the existing evidence base on its effectiveness as a recovery approach for problem gambling. To remedy this gap in the literature we conducted a scoping review of the literature on mutual aid for individuals experiencing problem gambling published between 2002 and 2015. We searched 13 databases and reviewed reference lists and websites of relevant organizations. We reviewed records for eligibility and extracted relevant data from eligible articles. Three reviewers independently assessed the methodological quality of the included studies using the Mixed Methods Appraisal Tool. We identified 17 studies in 25 publications that were eligible for inclusion. Most studies were conducted in the United States, were cross-sectional in design, and involved both male and female adult participants. Results indicate that the evidence for the effectiveness of GA either as a control condition or in conjunction with formal treatment or medication is inconsistent. An emphasis on patience, using the Serenity Prayer as a way to gain acceptance of financial matters and reality, and absolute assertion of identity as a "compulsive gambler" were identified as important aspects of GA's recovery culture. There is a need for large-scale randomized controlled trials to determine GA's effectiveness, as well as research exploring the mechanisms through which GA works, barriers to GA as a recovery approach, and the status of women in the fellowship.

  11. On the Anonymity Risk of Time-Varying User Profiles

    Directory of Open Access Journals (Sweden)

    Silvia Puglisi

    2017-04-01

    Full Text Available Websites and applications use personalisation services to profile their users, collect their patterns and activities and eventually use this data to provide tailored suggestions. User preferences and social interactions are therefore aggregated and analysed. Every time a user publishes a new post or creates a link with another entity, either another user, or some online resource, new information is added to the user profile. Exposing private data does not only reveal information about single users’ preferences, increasing their privacy risk, but can expose more about their network that single actors intended. This mechanism is self-evident in social networks where users receive suggestions based on their friends’ activities. We propose an information-theoretic approach to measure the differential update of the anonymity risk of time-varying user profiles. This expresses how privacy is affected when new content is posted and how much third-party services get to know about the users when a new activity is shared. We use actual Facebook data to show how our model can be applied to a real-world scenario.

  12. Sister-sister incest: data from an anonymous computerized survey.

    Science.gov (United States)

    Stroebel, Sandra S; O'Keefe, Stephen L; Griffee, Karen; Kuo, Shih-Ya; Beard, Keith W; Kommor, Martin J

    2013-01-01

    Retrospective data were entered anonymously by 1,521 adult women using a computer-assisted self-interview. Thirty-one participants were victims of sister-sister incest, 40 were victims of brother-sister incest, 19 were victims of father-daughter incest, 8 were victims of sexual abuse by an adult female (including one mother), and 232 were victims of sexual abuse by an adult male other than their father before reaching 18 years of age. The rest (1,203) served as controls. The victims of sister-sister incest had significantly more problematic outcomes than controls on many measures as adults. Victims of sister-sister incest were more depressed and more likely than controls to be distant from the perpetrator-sister and to have traded sex for money, experienced an unplanned pregnancy, engaged in four different types of masturbation, and engaged in 13 different same-sex behaviors. Our findings were consistent with other reports of early eroticization and persistent hypereroticization of incest victims.

  13. Delineating social network data anonymization via random edge perturbation

    KAUST Repository

    Xue, Mingqiang

    2012-01-01

    Social network data analysis raises concerns about the privacy of related entities or individuals. To address this issue, organizations can publish data after simply replacing the identities of individuals with pseudonyms, leaving the overall structure of the social network unchanged. However, it has been shown that attacks based on structural identification (e.g., a walk-based attack) enable an adversary to re-identify selected individuals in an anonymized network. In this paper we explore the capacity of techniques based on random edge perturbation to thwart such attacks. We theoretically establish that any kind of structural identification attack can effectively be prevented using random edge perturbation and show that, surprisingly, important properties of the whole network, as well as of subgraphs thereof, can be accurately calculated and hence data analysis tasks performed on the perturbed data, given that the legitimate data recipient knows the perturbation probability as well. Yet we also examine ways to enhance the walk-based attack, proposing a variant we call probabilistic attack. Nevertheless, we demonstrate that such probabilistic attacks can also be prevented under sufficient perturbation. Eventually, we conduct a thorough theoretical study of the probability of success of any}structural attack as a function of the perturbation probability. Our analysis provides a powerful tool for delineating the identification risk of perturbed social network data; our extensive experiments with synthetic and real datasets confirm our expectations. © 2012 ACM.

  14. Analytic neutrality, anonymity, abstinence, and elective self-disclosure.

    Science.gov (United States)

    Shill, Merton A

    2004-01-01

    Recent contributions to the psychoanalytic literature propose new ways of understanding analytic neutrality, anonymity, abstinence, and self-disclosure. They advocate elective self-disclosure by the analyst as an antidote to the allegedly game-playing quality of transference and resistance analysis. The analytic relationship, they assert, becomes unreal when attempts are made to observe the principles of neutrality and abstinence. Both are seen as ill-conceived because of the irreducible subjectivity and unwarranted authority of the analyst. These relational and interactional views are criticized because (1) they ignore the fact that transference and resistance analysis have from Freud onward been accepted as minimal criteria qualifying a clinical process as psychoanalytic; (2) elective self-disclosure carries metapsychological implications dismissing not only Freud's theory of motivation but motivation as a basic feature of human personality; (3) they do not recognize interpersonal relations as mental events and so do not consider the ego's ability to create intrapsychic representations of object relations; (4) elective self-disclosures within the empathic parameters of the analytic situation are themselves unreal compared to the reality of the patient's experience with other objects. Abstinence and neutrality as ideals facilitate maintenance of an internal holding environment or container for the analyst's countertransference.

  15. Use of WhatsApp in Higher Education: What's Up with Assessing Peers Anonymously?

    Science.gov (United States)

    Güler, Çetin

    2017-01-01

    The aim of this study is to investigate the use of WhatsApp application in anonymous peer assessment in higher education. The mobile phone application WhatsApp was used as both an anonymous and nonanonymous peer assessment tool in a classroom environment. The participants of the study were the students of two classes (sophomores and juniors), half…

  16. Anonymous Communication Policies for the Internet: Results and Recommendations of the AAAS Conference.

    Science.gov (United States)

    Teich, Al; Frankel, Mark S.; Kling, Rob; Lee, Yaching

    1999-01-01

    Reports the results of a conference on the Internet and anonymous communication organized by the American Association for the Advancement of Science (AAAS). Discusses how anonymous communications can be shaped by the law, education, and public awareness, and highlights the importance of involving all affected interests in policy development.…

  17. Toward Analysis of the Relations Among the Youth Counterculture, Telephone Hotlines, and Anonymity

    Science.gov (United States)

    Baizerman, Michael

    1974-01-01

    During the 1960's, there emerged innovative human service programs for youth. Among the actual differences in these programs compared to their older, established human service agencies was (is) the prominent position of the social value of client anonymity. This anonymity is examined in an attempt to understand its role. (RC)

  18. The Risk of a Halo Bias as a Reason to Keep Students Anonymous during Grading

    Science.gov (United States)

    Malouff, John M.; Emmerton, Ashley J.; Schutte, Nicola S.

    2013-01-01

    Experts have advocated anonymous grading as a means of eliminating actual or perceived evaluator bias in subjective student assessment. The utility of anonymity in assessment rests on whether information derived from student identity can unduly influence evaluation. The halo effect provides a conceptual background for why a bias might occur. In…

  19. Encouraging College Student Active Engagement in Learning: Student Response Methods and Anonymity

    Science.gov (United States)

    Barr, M. L.

    2017-01-01

    The purpose of this study was to examine the role of anonymity in encouraging college students to be more cognitively engaged in lectures. Kinesiology majors from three universities were asked to respond to questions during two consecutive lectures using response methods of opposing degrees of anonymity, one using "clickers" and the…

  20. Hacktivism 1-2-3: how privacy enhancing technologies change the face of anonymous hacktivism

    Directory of Open Access Journals (Sweden)

    Balázs Bodó

    2014-11-01

    Full Text Available This short essay explores how the notion of hacktivism changes due to easily accessible, military grade Privacy Enhancing Technologies (PETs. Privacy Enhancing Technologies, technological tools which provide anonymous communications and protect users from online surveillance enable new forms of online political activism. Through the short summary of the ad-hoc vigilante group Anonymous, this article describes hacktivism 1.0 as electronic civil disobedience conducted by outsiders. Through the analysis of Wikileaks, the anonymous whistleblowing website, it describes how strong PETs enable the development of hacktivism 2.0, where the source of threat is shifted from outsiders to insiders. Insiders have access to documents with which power can be exposed, and who, by using PETs, can anonymously engage in political action. We also describe the emergence of a third generation of hacktivists who use PETs to disengage and create their own autonomous spaces rather than to engage with power through anonymous whistleblowing.

  1. Attribute Utility Motivated k-anonymization of datasets to support the heterogeneous needs of biomedical researchers.

    Science.gov (United States)

    Ye, Huimin; Chen, Elizabeth S

    2011-01-01

    In order to support the increasing need to share electronic health data for research purposes, various methods have been proposed for privacy preservation including k-anonymity. Many k-anonymity models provide the same level of anoymization regardless of practical need, which may decrease the utility of the dataset for a particular research study. In this study, we explore extensions to the k-anonymity algorithm that aim to satisfy the heterogeneous needs of different researchers while preserving privacy as well as utility of the dataset. The proposed algorithm, Attribute Utility Motivated k-anonymization (AUM), involves analyzing the characteristics of attributes and utilizing them to minimize information loss during the anonymization process. Through comparison with two existing algorithms, Mondrian and Incognito, preliminary results indicate that AUM may preserve more information from original datasets thus providing higher quality results with lower distortion.

  2. Statistical disclosure limitation of health data based on Pk-anonymity.

    Science.gov (United States)

    Kimura, Eizen; Chida, Koji; Ikarashi, Dai; Hamada, Koki; Ishihara, Ken

    2012-01-01

    The Act for the Protection of Personal Information in Japan considers as personal information any quasi-identifier that may be used to obtain information that identifies individuals through comparisons with datasets. Studies using health records are not widely conducted because of the concern regarding the safety of anonymized health records. To increase the safety of such records, we used the Pk-anonymity method. In this method, attributes are probabilistically randomized and then reconstructions are performed on the basis of statistical information from perturbed data. Hence, it is expected to provide more precise statistics and more reliably preserve privacy than the traditional "k-anonymity" method. We anonymized health records, performed cross tabulation, and assessed the error rate using original data. This study shows that the Pk-anonymity method can be used to perform safety statistical disclosures with low error rates, even in small cases.

  3. A hidden service model based on HS-HS anonymous network

    Science.gov (United States)

    Meng, Yitong; Zhao, Xing; Fei, Jinlong; Zhu, Yuefei

    2017-10-01

    The Hidden Service provided by Tor anonymous network can effectively protect the anonymity and security of the Hidden server, this article through the analysis of the data packet structure of Tor, three jump transmission mechanism and link establishment protocol and Hidden Service communication process, in view of the Hidden node number too much, link building Service for too long and too redundant link problem. An improved hidden service model HS-HS is proposed that incorporating multiple transmission link and reuse, and at the same time will be important transit point for reuse protection link anonymity, through the ExperimenTor simulation environment test, verify the improved model of HS-HS can be more effective in guarantee anonymity and security, improve the overall efficiency of data transmission, to meet the needs of today's anonymous service.

  4. Social networks as mediators of the effect of Alcoholics Anonymous.

    Science.gov (United States)

    Kaskutas, Lee Ann; Bond, Jason; Humphreys, Keith

    2002-07-01

    This study tested the hypothesis that the relationship between Alcoholics Anonymous (AA) involvement and reduced substance use is partially explained (or 'mediated') by changes in social networks. This is a naturalistic longitudinal study of the course of alcohol problems. Study sites were the 10 largest public and private alcohol treatment programs in a northern California county. Three hundred and seventy-seven men and 277 women were recruited upon seeking treatment at study sites. At baseline and 1-year follow-up, we assessed alcohol consequences and dependence symptoms, consumption, social support for abstinence, pro-drinking social influences and AA involvement. In the structural equation model, AA involvement was a significant predictor of lower alcohol consumption and fewer related problems. The size of this effect decreased by 36% when network size and support for drinking were included as mediators. In logistic regression models predicting abstinence at follow-up, AA remained highly significant after including social network variables but was again reduced in magnitude. Thirty-day abstinence was predicted by AA involvement (OR=2.9), not having pro-drinking influences in one's network (OR=0.7) and having support for reducing consumption from people met in AA (versus no support; OR=3.4). In contrast, having support from non-AA members was not a significant predictor of abstinence. For alcohol-related outcomes other than abstinence, significant relationships were found for both AA-based and non-AA-based support. The type of social support specifically given by AA members, such as 24-hour availability, role modeling and experientially based advice for staying sober, may help to explain AA's mechanism of action. Results highlight the value of focusing on outcomes reflective of AA's goals (such as abstinence) when studying how AA works.

  5. Anonymity In Survey Courses as Tool for More Diverse Engagement

    Science.gov (United States)

    Samson, P. J.

    2017-12-01

    It is not uncommon that students in introductory survey courses are reluctant to participate in verbal inquiry. In a survey submitted to students of CLIMATE 102, Extreme Weather, over the past four semesters about 45% of male students professed comfort in asking verbal questions in a large lecture hall but less than 25% of females and only 15% of students for whom English is not their first language. Hence, large lecture hall courses may be inadvertently dissuading the inclusion of many of the students we wish to encourage to participate in our discipline. To combat this a system was used in CLIMATE 102 wherein students could pose questions digitally and anonymously. These questions could be seen by all and answered by all. The instructor and/or teaching assistant can also participate and answer or offer corrections to others' answers. The use of this system had three important outcomes: The number of questions posed during class time rose dramatically from previous semesters when only verbal questions were entertained. The number of questions in CLIMATE 102 with this system generally exceeded 500 per semester where the number of students 200. The number of per-capita questions from female students exceeded the male students, thus differences in gender inquiry was eliminated. The number of per-capita questions from students whose first language was not English equaled the native English-speaking students. While it is the goal of higher education to encourage students to participate verbally in class discussions it is important to provide a "safe" environment in the first year(s) as many students are initially uncomfortable participating verbally in class. We hypothesize, but have not researched, that through this process students have the opportunity to see that their questions are as valid as others' in the class and will subsequently gain the confidence to participate verbally.

  6. Humoral markers of active Epstein-Barr virus infection associate with anti-extractable nuclear antigen autoantibodies and plasma galectin-3 binding protein in systemic lupus erythematosus

    DEFF Research Database (Denmark)

    Rasmussen, N S; Nielsen, C T; Houen, G

    2016-01-01

    We investigated if signs of active Epstein-Barr virus and cytomegalovirus infections associate with certain autoantibodies and a marker of type I interferon activity in patients with systemic lupus erythematosus. IgM and IgG plasma levels against Epstein-Barr virus early antigen diffuse and cytom......We investigated if signs of active Epstein-Barr virus and cytomegalovirus infections associate with certain autoantibodies and a marker of type I interferon activity in patients with systemic lupus erythematosus. IgM and IgG plasma levels against Epstein-Barr virus early antigen diffuse...... and cytomegalovirus pp52 were applied as humoral markers of ongoing/recently active Epstein-Barr virus and cytomegalovirus infections, respectively. Plasma galectin-3 binding protein served as a surrogate marker of type I interferon activity. The measurements were conducted in 57 systemic lupus erythematosus patients...

  7. Decision no 2010-DC-0183 by the Nuclear Safety Authority on the 18. of May 2010 specifying instructions related to modalities of water sampling and consumption, and of release in the environment of liquid and gaseous effluents from the base nuclear installations no 46, no 74 and no 100 operated by Electricite de France-Societe Anonyme (EDF-SA) on the district of Saint-Laurent-Nouan (Loir-et-Cher department)

    International Nuclear Information System (INIS)

    2010-01-01

    After references to the different legal and official documents (codes, orders, minister's opinion, public surveys, administrative authorizations, local community opinion), this document specifies the instructions related to modalities of water sampling and consumption, and of release in the environment of liquid and gaseous effluents from some specific base nuclear installations. These instructions and provisions concern the general means implemented by the operator, records, the control by authorities, the limits of water sampling and consumption, the water sampling process, the sampling works and their maintenance and control, the release of liquid, gaseous and radioactive effluents, their control, and the information of authorities and of population

  8. (SSR) markers

    African Journals Online (AJOL)

    SAM

    2014-07-30

    Jul 30, 2014 ... al., 2004; Lefebvre et al., 2001; Moon et al., 2003; Paran et al., 1998; Prince et al., 1992). These markers have proven to be very useful in assessing genetic diversity and phylogeny, characterization of germplasm and detection of duplicates, parental verification in crosses, gene tagging in marker assisted ...

  9. (RAPD) markers

    African Journals Online (AJOL)

    Administrator

    2011-09-21

    Sep 21, 2011 ... RAPD markers reveal polymorphism among some Iranian pomegranate genotypes. Sci. Hortic. 111: 24-29. Shasany AK, Darokar MP, Dhawan S, Gupta AK, Gupta S, Shukla AK,. Patra NK, Khanuja SPS (2005). Use of RAPD and AFLP Markers to. Identify Inter- and Intraspecific Hybrids of Mentha. J. Hered.

  10. Discrimination of uranium chemo-toxic and radio-toxic effects: definition of biological markers for evaluating professional risks in nuclear industry

    International Nuclear Information System (INIS)

    Darolles, Carine

    2010-01-01

    Uranium (U) is a heavy metal that is also considered as an alpha emitter. Thus the origin of U toxicity is both chemical and radiological. The identification of bio-markers to discriminate chemical and radiological toxicity for a given U compound is required to assess accurately the health effects of isotopic mixtures such as depleted U in 235 U with a low specific activity. Data from the literature show that the best candidates are cytogenetic markers. In the present work, the assessment of bio-markers of U contamination was performed on three cellular models (mouse fibroblasts, rat lymphocytes and human lymphocytes) that were exposed to different isotopic mixtures of U. The cytokinesis-block micronucleus (MN) centromere assay was performed to discriminate the chemo-toxic and radio-toxic effects of U. This study showed that the evaluation of micronuclei in bi-nucleated cells could not assess U genotoxicity accurately. Instead, the assessment of centromere-negative micronuclei and nucleo-plasmic bridges correlated with the radio-toxic effects of U. The evaluation of centromere-positive micronuclei and micronuclei in mono-nucleated cells correlated with the chemo-toxic effects of U. These cytogenetic markers should be validated on different biological models and could be proposed to discriminate radiological and chemical toxicity of a given isotopic mixture of U. These four cytogenetic markers could be a useful complement of the classical dosimetric bio-markers for the assessment of internal uranium contamination. (author)

  11. Human spermatogonial markers.

    Science.gov (United States)

    von Kopylow, Kathrein; Spiess, Andrej-Nikolai

    2017-12-01

    In this review, we provide an up-to-date compilation of published human spermatogonial markers, with focus on the three nuclear subtypes A dark , A pale and B. In addition, we have extended our recently published list of putative spermatogonial markers with protein expression and RNA-sequencing data from the Human Protein Atlas and supported these by literature evidence. Most importantly, we have put substantial effort in acquiring a comprehensive list of new and potentially interesting markers by refiltering the raw data of 15 published germ cell expression datasets (four human, eleven rodent) and subsequent building of intersections to acquire a robust, cross-species set of spermatogonia-enriched or -specific transcripts. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  12. Human spermatogonial markers

    Directory of Open Access Journals (Sweden)

    Kathrein von Kopylow

    2017-12-01

    Full Text Available In this review, we provide an up-to-date compilation of published human spermatogonial markers, with focus on the three nuclear subtypes Adark, Apale and B. In addition, we have extended our recently published list of putative spermatogonial markers with protein expression and RNA-sequencing data from the Human Protein Atlas and supported these by literature evidence. Most importantly, we have put substantial effort in acquiring a comprehensive list of new and potentially interesting markers by refiltering the raw data of 15 published germ cell expression datasets (four human, eleven rodent and subsequent building of intersections to acquire a robust, cross-species set of spermatogonia-enriched or -specific transcripts.

  13. AIB-OR: improving onion routing circuit construction using anonymous identity-based cryptosystems.

    Science.gov (United States)

    Wang, Changji; Shi, Dongyuan; Xu, Xilei

    2015-01-01

    The rapid growth of Internet applications has made communication anonymity an increasingly important or even indispensable security requirement. Onion routing has been employed as an infrastructure for anonymous communication over a public network, which provides anonymous connections that are strongly resistant to both eavesdropping and traffic analysis. However, existing onion routing protocols usually exhibit poor performance due to repeated encryption operations. In this paper, we first present an improved anonymous multi-receiver identity-based encryption (AMRIBE) scheme, and an improved identity-based one-way anonymous key agreement (IBOWAKE) protocol. We then propose an efficient onion routing protocol named AIB-OR that provides provable security and strong anonymity. Our main approach is to use our improved AMRIBE scheme and improved IBOWAKE protocol in onion routing circuit construction. Compared with other onion routing protocols, AIB-OR provides high efficiency, scalability, strong anonymity and fault tolerance. Performance measurements from a prototype implementation show that our proposed AIB-OR can achieve high bandwidths and low latencies when deployed over the Internet.

  14. Anonymous birth law saves babies--optimization, sustainability and public awareness.

    Science.gov (United States)

    Grylli, Chryssa; Brockington, Ian; Fiala, Christian; Huscsava, Mercedes; Waldhoer, Thomas; Klier, Claudia M

    2016-04-01

    The aims of this study are to assess the impact of Austria's anonymous birth law from the time relevant statistical records are available and to evaluate the use of hatches versus anonymous hospital delivery. This study is a complete census of police-reported neonaticides (1975-2012) as well as anonymous births including baby hatches in Austria during 2002-2012. The time trends of neonaticide rates, anonymous births and baby hatches were analysed by means of Poisson and logistic regression model. Predicted and observed rates were derived and compared using a Bayesian Poisson regression model. Predicted numbers of neonaticides for the period of the active awareness campaign, 2002-2004, were more than three times larger than the observed number (p = 0.0067). Of the 365 women who benefitted from this legislation, only 11.5% chose to put their babies in a baby hatch. Since the law was introduced, a significant decreasing tendency of numbers of anonymous births (p = 047) was observed, while there was significant increase of neonaticide rates (p = 0.0001). The implementation of the anonymous delivery law is associated with a decrease in the number of police-reported neonaticides. The subsequent significantly decreasing numbers of anonymous births with an accompanying increase of neonaticides represents additional evidence for the effectiveness of the measure.

  15. Serbs in the poetry of Theodore Prodromos and anonymous Manganeios

    Directory of Open Access Journals (Sweden)

    Stanković Vlada

    2006-01-01

    Full Text Available Numerous rhetorical writings of the Comnenian period constitute a fruitful field of research, both with respect to historical data, i.e. hard historical facts hidden, though still recognizable, behind the peculiar and somewhat abstract mode of expression of the authors of the twelfth century, and with regard to the poetics of the literary works themselves, i.e. the internal elements characteristic not only for the genre chosen, but also for each particular author. A comparative, historical and literary approach to these works renders their sense clearer and their complex allusions more readily understood. This is a matter of some importance, since allusions constitute one of the basic elements of historical rhetoric, which reached its peak at the time of Emperor Manuel Komnenos (1143-1180, especially during the first half of his reign, i.e. till the end of the fifties of the twelfth century. The poetry of Theodore Prodromes and of the somewhat younger Anonymous ('Prodromos' Manganeios is an excellent example of this intertwining of historical and literary elements, i.e. of the presentation of historical data through rhetorical patterns. One has to concentrate on individual works attempting to determine, as far as possible, the date of composition, the circumstances of writing and the purpose of a particular poem, the occasion for which it was written and the character of the expected audience, in order to better understand both the poetry written by these two rhetoricians and the individual features of the authors, as well as their respective positions in the circle around Emperor Manuel Komnenos. The poems dealt with in the present paper stand out for calling the Serbs by their real name. This naming practice was invariably employed by both rhetoricians in cases when new achievements of the basileus were to be announced and proclaimed immediately after the event, on the occasions of first reports, first celebrations of the new victories and

  16. Anonymity and pseudonymity in whistleblowing to the U.S. Office of Research Integrity.

    Science.gov (United States)

    Price, A R

    1998-05-01

    Given the concerns expressed by members of the academic and legal community about whether (and how) to handle anonymous and pseudonymous allegations of scientific misconduct, this paper summaries the experiences of the Office of Research Integrity and its predecessor from 1989 through 1997. Although the record shows that research institutions and the ORI have treated such allegations seriously, the fraction of complainants to the ORI who remain anonymous is small (8% of 986 allegations); few anonymous complaints are sufficiently substantive to be pursued (4% of the 357 formal cases opened in the ORI); and only 1 of these 13 cases resulted in an ORI finding of scientific misconduct.

  17. Tumors markers

    International Nuclear Information System (INIS)

    Yamaguchi-Mizumoto, N.H.

    1989-01-01

    In order to study blood and cell components alterations (named tumor markers) that may indicate the presence of a tumor, several methods are presented. Aspects as diagnostic, prognostic, therapeutic value and clinical evaluation are discussed. (M.A.C.)

  18. Tumor Markers

    Science.gov (United States)

    ... only a small number of people will test positive for the disease who do not have it—in other words, it will result in very few false-positive results. Although tumor markers are extremely useful in ...

  19. Bone Markers

    Science.gov (United States)

    ... and Iron-binding Capacity (TIBC, UIBC) Trichomonas Testing Triglycerides Troponin Tryptase Tumor Markers Uric Acid Urinalysis Urine ... Replacement or Calcium Supplementation. Journal of Clinical Endocrinology & Metabolism Vol. 82, No. 6 1904-1910, 1997. N. ...

  20. The Use of a Human Breast Tumor Progression Series and a 3-D Culture Model to Determine if Nuclear Structure Could Provide a Molecular and Therapeutic Marker

    Science.gov (United States)

    2000-01-01

    J 17:3363-3371. human submandibular gland cell line (HSG) in vitro. Mol Fagotto F, Gluck U, Gumbiner BM (1998): Nuclear localiza- Biol Cell 6(suppl...Strculi, C. H., Schmidhauser, C., Korbrin, M., Bissell, M. J., and Derynck, R. and cancer in the mammary gland . Adv. Cancer Res., 75: 131-161, 1998...Command, 504 Scott Street, Fort Detrick, Maryland 21702-5012. 13. ABSTRACT (Maximum 200 Words) Alteration in nuclear structure is a hallmark of cancer

  1. Highly Informative Single-Copy Nuclear Microsatellite DNA Markers Developed Using an AFLP-SSR Approach in Black Spruce (Picea mariana) and Red Spruce (P. rubens)

    Science.gov (United States)

    Shi, Yong-Zhong; Forneris, Natascha; Rajora, Om P.

    2014-01-01

    Background Microsatellites or simple sequence repeats (SSRs) are highly informative molecular markers for various biological studies in plants. In spruce (Picea) and other conifers, the development of single-copy polymorphic genomic microsatellite markers is quite difficult, owing primarily to the large genome size and predominance of repetitive DNA sequences throughout the genome. We have developed highly informative single-locus genomic microsatellite markers in black spruce (Picea mariana) and red spruce (Picea rubens) using a simple but efficient method based on a combination of AFLP and microsatellite technologies. Principal Findings A microsatellite-enriched library was constructed from genomic AFLP DNA fragments of black spruce. Sequencing of the 108 putative SSR-containing clones provided 94 unique sequences with microsatellites. Twenty-two of the designed 34 primer pairs yielded scorable amplicons, with single-locus patterns. Fourteen of these microsatellite markers were characterized in 30 black spruce and 30 red spruce individuals drawn from many populations. The number of alleles at a polymorphic locus ranged from 2 to 18, with a mean of 9.3 in black spruce, and from 3 to 15, with a mean of 6.2 alleles in red spruce. The polymorphic information content or expected heterozygosity ranged from 0.340 to 0.909 (mean = 0.67) in black spruce and from 0.161 to 0.851 (mean = 0.62) in red spruce. Ten SSR markers showing inter-parental polymorphism inherited in a single-locus Mendelian mode, with two cases of distorted segregation. Primer pairs for almost all polymorphic SSR loci resolved microsatellites of comparable size in Picea glauca, P. engelmannii, P. sitchensis, and P. abies. Significance The AFLP-based microsatellite-enriched library appears to be a rapid, cost-effective approach for isolating and developing single-locus informative genomic microsatellite markers in black spruce. The markers developed should be useful in black spruce, red spruce

  2. Hacktivism 1-2-3: how privacy enhancing technologies change the face of anonymous hacktivism

    NARCIS (Netherlands)

    Bodó, B.

    2014-01-01

    This short essay explores how the notion of hacktivism changes due to easily accessible, military grade Privacy Enhancing Technologies (PETs). Privacy Enhancing Technologies, technological tools which provide anonymous communications and protect users from online surveillance enable new forms of

  3. The Role of the Anonymous Voice in Post-Publication Peer Review Versus Traditional Peer Review

    Directory of Open Access Journals (Sweden)

    Jaime A. Teixeira da Silva

    2015-12-01

    Full Text Available Traditional peer review (TPR has several limitations and weaknesses. Post-publication peer review is one practical way to repair the ills of TPR and reinforce it. A literature that is marked by errors is unhealthy and should, if given the opportunity, be corrected or further improved. The anonymous voice is one source of critique and differs from the blind peer review in TPR in which the reviewer remains anonymous to the authors and/or vice versa, but the identity is known to the editor. If unregulated, the anonymous voice can pose a threat to established editorial norms in TPR, to one of the most important criteria of science publishing, i.e., transparency, and to worthwhile discussion. Yet, if the anonymous voice is not heard, then a vast and potentially valuable pool of untapped opinions may be lost, opinions that may provide valuable solutions to improving TPR.

  4. Anonymous letters? DNA and fingerprints technologies combined to solve a case.

    Science.gov (United States)

    Barbaro, A; Cormaci, P; Teatino, A; La Marca, A; Barbaro, A

    2004-12-02

    Two brothers, living in two different cities, received two different anonymous letters. We performed latent prints development and DNA research on the letters and also on a glass used by a cousin suspected to be the letters' sender.

  5. Security Analysis and Improvement of an Anonymous Authentication Scheme for Roaming Services

    Directory of Open Access Journals (Sweden)

    Youngsook Lee

    2014-01-01

    Full Text Available An anonymous authentication scheme for roaming services in global mobility networks allows a mobile user visiting a foreign network to achieve mutual authentication and session key establishment with the foreign-network operator in an anonymous manner. In this work, we revisit He et al.’s anonymous authentication scheme for roaming services and present previously unpublished security weaknesses in the scheme: (1 it fails to provide user anonymity against any third party as well as the foreign agent, (2 it cannot protect the passwords of mobile users due to its vulnerability to an offline dictionary attack, and (3 it does not achieve session-key security against a man-in-the-middle attack. We also show how the security weaknesses of He et al.’s scheme can be addressed without degrading the efficiency of the scheme.

  6. To Speak or Not to Speak: Developing Legal Standards for Anonymous Speech on the Internet

    Directory of Open Access Journals (Sweden)

    Tomas A. Lipinski

    2002-01-01

    Full Text Available This paper explores recent developments in the regulation of Internet speech, in specific, injurious or defamatory speech and the impact such speech has on the rights of anonymous speakers to remain anonymous as opposed to having their identity revealed to plaintiffs or other third parties. The paper proceeds in four sections.  First, a brief history of the legal attempts to regulate defamatory Internet speech in the United States is presented. As discussed below this regulation has altered the traditional legal paradigm of responsibility and as a result creates potential problems for the future of anonymous speech on the Internet.  As a result plaintiffs are no longer pursuing litigation against service providers but taking their dispute directly to the anonymous speaker. Second, several cases have arisen in the United States where plaintiffs have requested that the identity of an anonymous Internet speaker be revealed.  These cases are surveyed.  Third, the cases are analyzed in order to determine the factors that courts require to be present before the identity of an anonymous speaker will be revealed.  The release is typically accomplished by the enforcement of a discovery subpoena instigated by the party seeking the identity of the anonymous speaker. The factors courts have used are as follows: jurisdiction, good faith (both internal and external, necessity (basic and sometimes absolute, and at times proprietary interest. Finally, these factors are applied in three scenarios--e-commerce, education, and employment--to guide institutions when adopting policies that regulate when the identity of an anonymous speaker--a customer, a student or an employee--would be released as part of an internal initiative, but would nonetheless be consistent with developing legal standards.

  7. An Enhancing Security Research of Tor Anonymous Communication to Against DDos Attacks

    OpenAIRE

    Feng Tao; Zhao Ming-Tao

    2017-01-01

    Tor (The Second Onion Router) is modified by the first generation onion router and known as the most prevalent anonymous communication system. According to the advantage of low latency, high confidentiality of transmission content, high security of communication channels and et al., Tor is widely used in anonymous Web browsing, instant message and so on. However, the vulnerability and blemish of Tor affect system security. An identity and Signcryption-based concurrent signature scheme was use...

  8. Risk factors for father-daughter incest: data from an anonymous computerized survey.

    Science.gov (United States)

    Stroebel, Sandra S; Kuo, Shih-Ya; O'Keefe, Stephen L; Beard, Keith W; Swindell, Sam; Kommor, Martin J

    2013-12-01

    Retrospective data from 2,034 female participants, provided anonymously using a computer-assisted self-interview, were used to identify risk factors for father-daughter incest (FDI). A total of 51 participants had reported having experienced FDI. The risk factors identified within the nuclear family by the multiple logistic regression analysis included the following: (a) Having parents whose relationship included verbal or physical fighting or brutality increased the likelihood of FDI by approximately 5 times; (b) families accepting father-daughter nudity as measured by a scale with values ranging from 0 to 4 increased the likelihood of FDI by approximately 2 times for each unit value increase of 1 above 0; (c) demonstrating maternal affection protected against FDI. The likelihood of being a victim of FDI was highest if the participant's mother never kissed or hugged her; it decreased by 0.44 for a 1-unit increase in affection and by 0.19 times for a 2-unit increase; and (d) being in homes headed by single-parent mothers or where divorce or death of the father had resulted in a man other than the biological father living in the home increased the risk of FDI by approximately 3.2 times. The results were consistent with the idea that FDI in many families was the cumulative result of a circular pattern of interactions, a finding that has implications for treatment of the perpetrator, the victim, and the families. The data also suggested it may be possible to design an information program for parents that will result in reducing the risk of FDI in families implementing the program's recommendations.

  9. Etiological Risk Factors for Sibling Incest: Data From an Anonymous Computer-Assisted Self-Interview.

    Science.gov (United States)

    Griffee, Karen; Swindell, Sam; O'Keefe, Stephen L; Stroebel, Sandra S; Beard, Keith W; Kuo, Shih-Ya; Stroupe, Walter

    2016-10-01

    Retrospective data from 1,821 women and 1,064 men with one or more siblings, provided anonymously using a computer-assisted self-interview, were used to identify risk factors for sibling incest (SI); 137 were participants in SI. In order of decreasing predictive power, the risk factors identified by the multiple logistic regression analysis included ever having shared a bed for sleeping with a sibling, parent-child incest (PCI), family nudity, low levels of maternal affection, and ever having shared a tub bath with a sibling. The results were consistent with the idea that SI in many families was the cumulative result of four types of parental behaviors: (a) factors that lower external barriers to sexual behavior (e.g., permitting co-sleeping or co-bathing of sibling dyads), (b) factors that encourage nudity of children within the nuclear family and permit children to see the parent's genitals, (c) factors that lead to the siblings relying on one another for affection (e.g., diminished maternal affection), and (d) factors that eroticize young children (e.g., child sexual abuse [CSA] by a parent). Thirty-eight of the 137 SI participants were participants in coerced sibling incest (CSI). In order of decreasing predictive power, risk factors for CSI identified by multiple logistic regression analysis included ever having shared a bed for sleeping with a brother, PCI, witnessing parental physical fighting, and family nudity. SI was more likely to have been reported as CSI if the sibling had touched the reporting sibling's genitals, and less likely to have been reported as CSI if the siblings had shared a bed. © The Author(s) 2014.

  10. Verbal Venting in the Social Web: Effects of Anonymity and Group Norms on Aggressive Language Use in Online Comments

    Directory of Open Access Journals (Sweden)

    Leonie Rösner

    2016-08-01

    Full Text Available Scholars often blame the occurrence of aggressive behavior in online discussions on the anonymity of the Internet; however, even on today’s less anonymous platforms, such as social networking sites, users write plenty of aggressive comments, which can elicit a whole wave of negative remarks. Drawing on the social identity and deindividuation effects (SIDE model, this research conducts a laboratory experiment with a 2 (anonymity vs. no anonymity × 2 (aggressive norm vs. non-aggressive norm between-subjects design in order to disentangle the effects of anonymity, social group norms, and their interactions on aggressive language use in online comments. Results reveal that participants used more aggressive expressions in their comments when peer comments on a blog included aggressive wording (i.e., the social group norm was aggressive. Anonymity had no direct effect; however, we found a tendency that users’ conformity to an aggressive social norm of commenting is stronger in an anonymous environment.

  11. (SSR) markers

    African Journals Online (AJOL)

    aghomotsegin

    Unknown. Unknown. V. vinifera L. 2000s. Chile. Stary goru. Ancient variety of Japan. V. vinifera L. 1980s. Japan. Medoc Noir. Unknown. V. vinifera L. 1980s. France. Vidal Blanc. Ugni blanc × seyval blanc. V. vinifera L. 1940s. France. Table 2. Summary of genetic variation statistics for the 19 simple sequence repeat markers ...

  12. (ISSR) markers

    African Journals Online (AJOL)

    Jane

    2011-07-25

    Jul 25, 2011 ... Heredity, 65: 179-188. Galvan MZ, Bornet B, Balatti PA, Branchard M (2003). Inter simple sequence repeat (ISSR) markers as a tool for the assessment of both genetic diversity and gene pool origin in common bean (Phaseolus vulgaris L.). Euphytica, 132: 297-301. Kojima T, Nagaoka T, Noda K, Ogihara Y ...

  13. Estimates of Non-Heterosexual Prevalence: The Roles of Anonymity and Privacy in Survey Methodology.

    Science.gov (United States)

    Robertson, Ronald E; Tran, Felix W; Lewark, Lauren N; Epstein, Robert

    2017-08-07

    When do people feel comfortable enough to provide honest answers to sensitive questions? Focusing specifically on sexual orientation prevalence-a measure that is sensitive to the pressures of heteronormativity-the present study was conducted to examine the variability in U.S. estimates of non-heterosexual identity prevalence and to determine how comfortable people are with answering questions about their sexual orientation when asked through commonly used survey modes. We found that estimates of non-heterosexual prevalence in the U.S. increased as the privacy and anonymity of the survey increased. Utilizing an online questionnaire, we rank-ordered 16 survey modes by asking people to rate their level of comfort with each mode in the context of being asked questions about their sexual orientation. A demographically diverse sample of 652 individuals in the U.S. rated each mode on a scale from -5 (very uncomfortable) to +5 (very comfortable). Modes included anonymous (name not required) and non-anonymous (name required) versions of questions, as well as self-administered and interviewer-administered versions. Subjects reported significantly higher mean comfort levels with anonymous modes than with non-anonymous modes and significantly higher mean comfort levels with self-administered modes than with interviewer-administered modes. Subjects reported the highest mean comfort level with anonymous online surveys and the lowest with non-anonymous personal interviews that included a video recording. Compared with the estimate produced by an online survey with a nationally representative sample, surveys utilizing more intrusive methodologies may have underestimated non-heterosexual prevalence in the U.S. by between 50 and 414%. Implications for public policy are discussed.

  14. The cost of quality: Implementing generalization and suppression for anonymizing biomedical data with minimal information loss.

    Science.gov (United States)

    Kohlmayer, Florian; Prasser, Fabian; Kuhn, Klaus A

    2015-12-01

    With the ARX data anonymization tool structured biomedical data can be de-identified using syntactic privacy models, such as k-anonymity. Data is transformed with two methods: (a) generalization of attribute values, followed by (b) suppression of data records. The former method results in data that is well suited for analyses by epidemiologists, while the latter method significantly reduces loss of information. Our tool uses an optimal anonymization algorithm that maximizes output utility according to a given measure. To achieve scalability, existing optimal anonymization algorithms exclude parts of the search space by predicting the outcome of data transformations regarding privacy and utility without explicitly applying them to the input dataset. These optimizations cannot be used if data is transformed with generalization and suppression. As optimal data utility and scalability are important for anonymizing biomedical data, we had to develop a novel method. In this article, we first confirm experimentally that combining generalization with suppression significantly increases data utility. Next, we proof that, within this coding model, the outcome of data transformations regarding privacy and utility cannot be predicted. As a consequence, existing algorithms fail to deliver optimal data utility. We confirm this finding experimentally. The limitation of previous work can be overcome at the cost of increased computational complexity. However, scalability is important for anonymizing data with user feedback. Consequently, we identify properties of datasets that may be predicted in our context and propose a novel and efficient algorithm. Finally, we evaluate our solution with multiple datasets and privacy models. This work presents the first thorough investigation of which properties of datasets can be predicted when data is anonymized with generalization and suppression. Our novel approach adopts existing optimization strategies to our context and combines different

  15. Utility of γH2AX as a molecular marker of DNA double-strand breaks in nuclear medicine: applications to radionuclide therapy employing auger electron-emitting isotopes.

    Science.gov (United States)

    Mah, Li-Jeen; Orlowski, Christian; Ververis, Katherine; El-Osta, Assam; Karagiannis, Tom C

    2011-01-01

    There is an intense interest in the development of radiopharmaceuticals for cancer therapy. In particular, radiopharmaceuticals which involve targeting radionuclides specifically to cancer cells with the use of monoclonal antibodies (radioimmunotherapy) or peptides (targeted radiotherapy) are being widely investigated. For example, the ultra-short range Auger electron-emitting isotopes, which are discussed in this review, are being considered in the context of DNAtargeted radiotherapy. The efficient quantitative evaluation of the levels of damage caused by such potential radiopharmaceuticals is required for assessment of therapeutic efficacy and determination of relevant doses for successful treatment. The DNA double-strand break surrogate marker, γH2AX, has emerged as a useful biomonitor of damage and thus effectiveness of treatment, offering a highly specific and sensitive means of assessment. This review will cover the potential applications of γH2AX in nuclear medicine, in particular radionuclide therapy.

  16. BIX Certificates: Cryptographic Tokens for Anonymous Transactions Based on Certificates Public Ledger

    Directory of Open Access Journals (Sweden)

    Sead Muftic

    2016-12-01

    Full Text Available With the widespread use of Internet, Web, and mobile technologies, a new category of applications and transactions that requires anonymity is gaining increased interest and importance. Examples of such new applications are innovative payment systems, digital notaries, electronic voting, documents sharing, electronic auctions, medical applications, and many others. In addition to anonymity, these applications and transactions also require standard security services: identification, authentication, and authorization of users and protection of their transactions. Providing those services in combination with anonymity is an especially challenging issue, because all security services require explicit user identification and authentication. To solve this issue and enable applications with security and also anonymity we introduce a new type of cryptographically encapsulated objects called BIX certificates. “BIX” is an abbreviation for “Blockchain Information Exchange.” Their purpose is equivalent to X.509 certificates: to support security services for users and transactions, but also enhanced with anonymity. This paper describes the structure and attributes of BIX certificate objects and all related protocols for their creation, distribution, and use. The BIX Certification Infrastructure (BCI as a distributed public ledger is also briefly described.

  17. A Lightweight Anonymous Authentication Protocol with Perfect Forward Secrecy for Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Ling Xiong

    2017-11-01

    Full Text Available Due to their frequent use in unattended and hostile deployment environments, the security in wireless sensor networks (WSNs has attracted much interest in the past two decades. However, it remains a challenge to design a lightweight authentication protocol for WSNs because the designers are confronted with a series of desirable security requirements, e.g., user anonymity, perfect forward secrecy, resistance to de-synchronization attack. Recently, the authors presented two authentication schemes that attempt to provide user anonymity and to resist various known attacks. Unfortunately, in this work we shall show that user anonymity of the two schemes is achieved at the price of an impractical search operation—the gateway node may search for every possible value. Besides this defect, they are also prone to smart card loss attacks and have no provision for perfect forward secrecy. As our main contribution, a lightweight anonymous authentication scheme with perfect forward secrecy is designed, and what we believe the most interesting feature is that user anonymity, perfect forward secrecy, and resistance to de-synchronization attack can be achieved at the same time. As far as we know, it is extremely difficult to meet these security features simultaneously only using the lightweight operations, such as symmetric encryption/decryption and hash functions.

  18. Anonymization for outputs of population health and health services research conducted via an online data center.

    Science.gov (United States)

    O'Keefe, Christine M; Westcott, Mark; O'Sullivan, Maree; Ickowicz, Adrien; Churches, Tim

    2017-05-01

    Online data centers (ODCs) are becoming increasingly popular for making health-related data available for research. Such centers provide good privacy protection during analysis by trusted researchers, but privacy concerns may still remain if the system outputs are not sufficiently anonymized. In this article, we propose a method for anonymizing analysis outputs from ODCs for publication in academic literature. We use as a model system the Secure Unified Research Environment, an online computing system that allows researchers to access and analyze linked health-related data for approved studies in Australia. This model system suggests realistic assumptions for an ODC that, together with literature and practice reviews, inform our solution design. We propose a two-step approach to anonymizing analysis outputs from an ODC. A data preparation stage requires data custodians to apply some basic treatments to the dataset before making it available. A subsequent output anonymization stage requires researchers to use a checklist at the point of downloading analysis output. The checklist assists researchers with highlighting potential privacy concerns, then applying appropriate anonymization treatments. The checklist can be used more broadly in health care research, not just in ODCs. Ease of online publication as well as encouragement from journals to submit supplementary material are likely to increase both the volume and detail of analysis results publicly available, which in turn will increase the need for approaches such as the one suggested in this paper.

  19. A Lightweight Anonymous Authentication Protocol with Perfect Forward Secrecy for Wireless Sensor Networks.

    Science.gov (United States)

    Xiong, Ling; Peng, Daiyuan; Peng, Tu; Liang, Hongbin; Liu, Zhicai

    2017-11-21

    Due to their frequent use in unattended and hostile deployment environments, the security in wireless sensor networks (WSNs) has attracted much interest in the past two decades. However, it remains a challenge to design a lightweight authentication protocol for WSNs because the designers are confronted with a series of desirable security requirements, e.g., user anonymity, perfect forward secrecy, resistance to de-synchronization attack. Recently, the authors presented two authentication schemes that attempt to provide user anonymity and to resist various known attacks. Unfortunately, in this work we shall show that user anonymity of the two schemes is achieved at the price of an impractical search operation-the gateway node may search for every possible value. Besides this defect, they are also prone to smart card loss attacks and have no provision for perfect forward secrecy. As our main contribution, a lightweight anonymous authentication scheme with perfect forward secrecy is designed, and what we believe the most interesting feature is that user anonymity, perfect forward secrecy, and resistance to de-synchronization attack can be achieved at the same time. As far as we know, it is extremely difficult to meet these security features simultaneously only using the lightweight operations, such as symmetric encryption/decryption and hash functions.

  20. Formal Security-Proved Mobile Anonymous Authentication Protocols with Credit-Based Chargeability and Controllable Privacy

    Directory of Open Access Journals (Sweden)

    Chun-I Fan

    2016-06-01

    Full Text Available Smart mobile phones are widely popularized and advanced mobile communication services are provided increasingly often, such that ubiquitous computing environments will soon be a reality. However, there are many security threats to mobile networks and their impact on security is more serious than that in wireline networks owing to the features of wireless transmissions and the ubiquity property. The secret information which mobile users carry may be stolen by malicious entities. To guarantee the quality of advanced services, security and privacy would be important issues when users roam within various mobile networks. In this manuscript, an anonymous authentication scheme will be proposed to protect the security of the network system and the privacy of users. Not only does the proposed scheme provide mutual authentication between each user and the system, but also each user’s identity is kept secret against anyone else, including the system. Although the system anonymously authenticates the users, it can still generate correct bills to charge these anonymous users via a credit-based solution instead of debit-based ones. Furthermore, our protocols also achieve fair privacy which allows the judge to revoke the anonymity and trace the illegal users when they have misused the anonymity property, for example, if they have committed crimes. Finally, in this paper, we also carry out complete theoretical proofs on each claimed security property.

  1. An Anonymous Access Authentication Scheme Based on Proxy Ring Signature for CPS-WMNs

    Directory of Open Access Journals (Sweden)

    Tianhan Gao

    2017-01-01

    Full Text Available Access security and privacy have become a bottleneck for the popularization of future Cyber-Physical System (CPS networks. Furthermore, users’ need for privacy-preserved access during movement procedure is more urgent. To address the anonymous access authentication issue for CPS Wireless Mesh Network (CPS-WMN, a novel anonymous access authentication scheme based on proxy ring signature is proposed. A hierarchical authentication architecture is presented first. The scheme is then achieved from the aspect of intergroup and intragroup anonymous mutual authentication through proxy ring signature mechanism and certificateless signature mechanism, respectively. We present a formal security proof of the proposed protocol with SVO logic. The simulation and performance analysis demonstrate that the proposed scheme owns higher efficiency and adaptability than the typical one.

  2. Between control and hacker activism: the political actions of Anonymous Brasil.

    Science.gov (United States)

    Machado, Murilo Bansi

    2015-12-01

    This paper addresses the political actions of Anonymous, the principal expression of current hacker activism, arguing that hacktivism is a form of political resistance in control societies. To this end, it focuses on studying the Brazilian, hacktivist facet of the collective. In order to stress its political character, it scrutinizes the principal expressions of hacking in the literature. It describes motivations, methods and the ethics of its political actions, based on a comparative analysis of two operations carried out by Brazilian Anonymous adherents in 2012: #OpWeeksPayment and #OpGlobo. And it finishes by identifying four of its main forms of political engagement: promotion of anonymity; "evangelization;" the formation of distributed networks; and the fact that the collective carries out and facilitates several types of political actions.

  3. RSSI-Based User Centric Anonymization for Location Privacy in Vehicular Networks

    Science.gov (United States)

    Wei, Yu-Chih; Chen, Yi-Ming; Shan, Hwai-Ling

    In Vehicular Networks, for enhancing driving safety as well as supporting other applications, vehicles periodically broadcast safety messages with their precise position information to neighbors. However, these broadcast messages make it easy to track specific vehicles and will likely lead to compromise of personal privacy. Unfortunately, current location privacy enhancement methodologies in VANET, including Pseudonymization, K-anonymity, Random silent period, Mix-zones and path confusion, all suffer some shortcomings. In this paper, we propose a RSSI (Received Signal Strength Indicator)-based user centric anonymization model, which can significantly enhance the location privacy and at the same time ensure traffic safety. Simulations are performed to show the advantages of the proposed method. In comparison with traditional random silent period method, our method can increase at least 47% of anonymity in both simple and correlation tracking.

  4. Recipient screening in IVF: First data from women undergoing anonymous oocyte donation in Dublin

    Directory of Open Access Journals (Sweden)

    Salma Umme

    2011-04-01

    Full Text Available Abstract Background Guidelines for safe gamete donation have emphasised donor screening, although none exist specifically for testing oocyte recipients. Pre-treatment assessment of anonymous donor oocyte IVF treatment in Ireland must comply with the European Union Tissues and Cells Directive (Directive 2004/23/EC. To determine the effectiveness of this Directive when applied to anonymous oocyte recipients in IVF, we reviewed data derived from selected screening tests performed in this clinical setting. Methods Data from tests conducted at baseline for all women enrolling as recipients (n = 225 in the anonymous oocyte donor IVF programme at an urban IVF referral centre during a 24-month period were analysed. Patient age at programme entry and clinical pregnancy rate were also tabulated. All recipients had at least one prior negative test for HIV, Hepatitis B/C, chlamydia, gonorrhoea and syphilis performed by her GP or other primary care provider before reproductive endocrinology consultation. Results Mean (±SD age for donor egg IVF recipients was 40.7 ± 4.2 yrs. No baseline positive chlamydia, gonorrhoea or syphilis screening results were identified among recipients for anonymous oocyte donation IVF during the assessment interval. Mean pregnancy rate (per embryo transfer in this group was 50.5%. Conclusion When tests for HIV, Hepatitis B/C, chlamydia, gonorrhoea and syphilis already have been confirmed to be negative before starting the anonymous donor oocyte IVF sequence, additional (repeat testing on the recipient contributes no new clinical information that would influence treatment in this setting. Patient safety does not appear to be enhanced by application of Directive 2004/23/EC to recipients of anonymous donor oocyte IVF treatment. Given the absence of evidence to quantify risk, this practice is difficult to justify when applied to this low-risk population.

  5. Children from anonymous donors: an inquiry into homosexual and heterosexual parents' attitudes.

    Science.gov (United States)

    Brewaeys, A; Ponjaert-Kristoffersen, I; Van Steirteghem, A C; Devroey, P

    1993-01-01

    This study compared two groups of homosexual and heterosexual parents with respect to their attitudes towards the donor-origin of their children. All couples had applied at the Fertility Clinic for artificial insemination with anonymous donor sperm (AID). Both groups had used anonymous donors in order to conceive. However, the sexual orientation of the parents and the presence or absence of a social father was different in the two groups. By comparing such different families it was hoped to obtain insight into those factors which influence parents' attitudes concerning donor insemination. Twenty-five lesbian and 25 heterosexual parents were interviewed. The open-ended questionnaires solicited information on the following issues: attitudes towards secrecy/disclosure of the use of a donor, views on anonymity/identity registration of the donor, parents' cognitive and emotional representation of the donor. Response rates differed between the groups: all homosexual parents consented to the interview and 44% of the heterosexual parents did so. Parents' attitudes depended on several variables. The different family structures were related to different motivations for AID treatment. For heterosexual couples, the use of a donor offered them the opportunity to become a 'normal family'. For homosexual couples, creating a two-mother family unit meant going one step further in 'being different'. Attitudes towards the use of a donor were consequently different: heterosexual couples chose secrecy and donor anonymity. Homosexual parents intended to inform their children. Of these homosexual parents, 40% would prefer the identity of the donor to be registered. This evolution towards removal of the anonymity seemed to be encouraged by the openness surrounding the use of a donor itself. In both groups it remained difficult to reduce the donor to an anonymous sperm cell, fantasies and questions about the donor continued to exist over the years.

  6. Recipient screening in IVF: First data from women undergoing anonymous oocyte donation in Dublin

    LENUS (Irish Health Repository)

    Walsh, Anthony PH

    2011-04-20

    Abstract Background Guidelines for safe gamete donation have emphasised donor screening, although none exist specifically for testing oocyte recipients. Pre-treatment assessment of anonymous donor oocyte IVF treatment in Ireland must comply with the European Union Tissues and Cells Directive (Directive 2004\\/23\\/EC). To determine the effectiveness of this Directive when applied to anonymous oocyte recipients in IVF, we reviewed data derived from selected screening tests performed in this clinical setting. Methods Data from tests conducted at baseline for all women enrolling as recipients (n = 225) in the anonymous oocyte donor IVF programme at an urban IVF referral centre during a 24-month period were analysed. Patient age at programme entry and clinical pregnancy rate were also tabulated. All recipients had at least one prior negative test for HIV, Hepatitis B\\/C, chlamydia, gonorrhoea and syphilis performed by her GP or other primary care provider before reproductive endocrinology consultation. Results Mean (±SD) age for donor egg IVF recipients was 40.7 ± 4.2 yrs. No baseline positive chlamydia, gonorrhoea or syphilis screening results were identified among recipients for anonymous oocyte donation IVF during the assessment interval. Mean pregnancy rate (per embryo transfer) in this group was 50.5%. Conclusion When tests for HIV, Hepatitis B\\/C, chlamydia, gonorrhoea and syphilis already have been confirmed to be negative before starting the anonymous donor oocyte IVF sequence, additional (repeat) testing on the recipient contributes no new clinical information that would influence treatment in this setting. Patient safety does not appear to be enhanced by application of Directive 2004\\/23\\/EC to recipients of anonymous donor oocyte IVF treatment. Given the absence of evidence to quantify risk, this practice is difficult to justify when applied to this low-risk population.

  7. Darknet and bitcoin, the obscure and anonymous side of the internet in healthcare.

    Science.gov (United States)

    Masoni, Marco; Guelfi, Maria Renza; Gensini, Gian Franco

    2016-11-14

    Illegal activities prosecutable by law in the real life can be committed on the internet alike. In the healthcare domain, we refer mainly to selling of illegal and counterfeit drugs, exchange of pedo-pornographic material and marketing of stolen medical records. These illegal activities are made easier by recent developments of the Internet that medical community must be aware of: darknet and bitcoin. The first allows anonymous surfing and the last anonymous financial transactions. After discussing which healthcare areas are affected by these technological developments of the Internet and the deriving consequences, then the Authors express their opinion on what actions can be taken to protect internet community.

  8. An Enhancing Security Research of Tor Anonymous Communication to Against DDos Attacks

    Directory of Open Access Journals (Sweden)

    Feng Tao

    2017-01-01

    Full Text Available Tor (The Second Onion Router is modified by the first generation onion router and known as the most prevalent anonymous communication system. According to the advantage of low latency, high confidentiality of transmission content, high security of communication channels and et al., Tor is widely used in anonymous Web browsing, instant message and so on. However, the vulnerability and blemish of Tor affect system security. An identity and Signcryption-based concurrent signature scheme was used to prevent the behaviors of attackers from inserting controlled nodes and conspiring to make DDos attacks. The integrated security of Tor system was enhanced in our scheme. In addition we have proved the scheme.

  9. Relationship between two androgenetic clam species, Corbicula leana and Corbicula fluminea, inferred from mitochondrial cytochrome b and nuclear 28S rRNA markers.

    Science.gov (United States)

    Komaru, Akira; Yamada, Mitsuya; Houki, Shouji

    2013-05-01

    Two shell color types, yellow (type I) and brown (type II), of hermaphrodite Corbicula fluminea clams from Ritto, Shiga Prefecture, Japan, are sympatric with both male and hermaphrodite Corbicula leana. In the present study, the mitochondrial DNA (mtDNA) cytochrome b and nuclear 28S rRNA genes of C. fluminea were sequenced to construct a haplotype network in order to investigate the genetic relationship with C. leana. Ninety C. fluminea samples revealed only two cytb haplotypes; the majority (97.8%) were CB7, while the remainder were CB1. In C. leana, only CB1 was detected in hermaphrodites, but both CB1 and CB7 were detected in males. Nuclear 28S rRNA haplotypes of C. fluminea type I individuals were divergent from those of hermaphrodite C. leana. However, C. fluminea type I clams shared haplotypes with male C. leana individuals, whereas C. fluminea type II individuals shared haplotypes with both hermaphrodite and male C. leana samples. These results suggest that it may be difficult to define a clear genetic border between these species.

  10. Compatibility of Adlerian Theory and Practice with the Philosophy and Practices of Alcoholics Anonymous.

    Science.gov (United States)

    Carroll, Jane J.

    1999-01-01

    Tenets of Adlerian theory and practice are compatible with the philosophy and practices of Alcoholics Anonymous. Counselors can expect treatment approaches based on Adlerian counseling theory to be congruent with 12-step practices of individuals who are in recovery from alcohol dependence. (Author)

  11. Bayesian modeling of consumer behavior in the presence of anonymous visits

    Science.gov (United States)

    Novak, Julie Esther

    Tailoring content to consumers has become a hallmark of marketing and digital media, particularly as it has become easier to identify customers across usage or purchase occasions. However, across a wide variety of contexts, companies find that customers do not consistently identify themselves, leaving a substantial fraction of anonymous visits. We develop a Bayesian hierarchical model that allows us to probabilistically assign anonymous sessions to users. These probabilistic assignments take into account a customer's demographic information, frequency of visitation, activities taken when visiting, and times of arrival. We present two studies, one with synthetic and one with real data, where we demonstrate improved performance over two popular practices (nearest-neighbor matching and deleting the anonymous visits) due to increased efficiency and reduced bias driven by the non-ignorability of which types of events are more likely to be anonymous. Using our proposed model, we avoid potential bias in understanding the effect of a firm's marketing on its customers, improve inference about the total number of customers in the dataset, and provide more precise targeted marketing to both previously observed and unobserved customers.

  12. Sexuality Information Needs of Latino and African American Ninth Graders: A Content Analysis of Anonymous Questions

    Science.gov (United States)

    Angulo-Olaiz, Francisca; Goldfarb, Eva S.; Constantine, Norman A.

    2014-01-01

    This study used qualitative content analysis to examine anonymous questions about sex and sexuality submitted by Latino and African American adolescents in Los Angeles, California, classrooms. The majority of questions asked about sexuality and sexual behavior, or anatomy and physiology, with fewer questions about pregnancy and pregnancy…

  13. Anonymous Multi-Receiver Identity-Based Authenticated Encryption with CCA Security

    Directory of Open Access Journals (Sweden)

    Chun-I Fan

    2015-10-01

    Full Text Available In a multi-receiver encryption system, a sender chooses a set of authorized receivers and sends them a message securely and efficiently, as the message is well encrypted and only one ciphertext corresponding to the message is generated no matter how many receivers the sender has chosen. It can be applied to video conferencing systems, pay-per-view channels, remote education, and so forth. Due to privacy considerations, an authorized receiver may not expect that his identity is revealed. In 2010, anonymous multi-receiver identity-based (ID-based encryption was first discussed, and furthermore, many works on the topic have been presented so far. Unfortunately, we find that all of those schemes fail to prove the chosen ciphertext attacks (CCA security in either confidentiality or anonymity. In this manuscript, we propose the first anonymous multi-receiver ID-based authenticated encryption scheme with CCA security in both confidentiality and anonymity. In the proposed scheme, the identity of the sender of a ciphertext can be authenticated by the receivers after a successful decryption. In addition, the proposed scheme also is the first CCA-secure one against insider attacks. Moreover, only one pairing computation is required in decryption.

  14. Security Enhanced Anonymous Multiserver Authenticated Key Agreement Scheme Using Smart Cards and Biometrics

    Science.gov (United States)

    Choi, Younsung; Nam, Junghyun; Lee, Donghoon; Kim, Jiye; Jung, Jaewook; Won, Dongho

    2014-01-01

    An anonymous user authentication scheme allows a user, who wants to access a remote application server, to achieve mutual authentication and session key establishment with the server in an anonymous manner. To enhance the security of such authentication schemes, recent researches combined user's biometrics with a password. However, these authentication schemes are designed for single server environment. So when a user wants to access different application servers, the user has to register many times. To solve this problem, Chuang and Chen proposed an anonymous multiserver authenticated key agreement scheme using smart cards together with passwords and biometrics. Chuang and Chen claimed that their scheme not only supports multiple servers but also achieves various security requirements. However, we show that this scheme is vulnerable to a masquerade attack, a smart card attack, a user impersonation attack, and a DoS attack and does not achieve perfect forward secrecy. We also propose a security enhanced anonymous multiserver authenticated key agreement scheme which addresses all the weaknesses identified in Chuang and Chen's scheme. PMID:25276847

  15. Towards an anonymous access control and accountability scheme for cloud computing

    DEFF Research Database (Denmark)

    Jensen, Meiko; Schäge, Sven; Schwenk, Jörg

    2010-01-01

    An important aspect of trust in cloud computing consists in preventing the cloud provider from misusing the user's data. In this work-in-progress paper, we propose the approach of data anonymization to solve this problem. As this directly leads to problems of cloud usage accounting, we also propose...

  16. Alcoholics anonymous, other 12-step movements and psychotherapy in the US population, 1990.

    Science.gov (United States)

    Room, R; Greenfield, T

    1993-04-01

    Based on the 1990 US National Alcohol Survey, this note provides the first available comprehensive findings on self-reported utilization of a variety of sources of personal support and counselling for alcohol and other problems. Respondents were queried about lifetime attendance and number of times they went to identified sources of help in the prior year. Twelve-step groups included Alcoholics Anonymous, Al-Anon, Adult Children of Alcoholics, and other non-alcohol-oriented groups like Gamblers Anonymous, Narcotics Anonymous, and Overeaters Anonymous; additional questions inquired about support or therapy groups and individual counselling for non-alcohol problems. Of the US adult population, 9% have been to an AA meeting at some time, 3.6% in the prior year, only about one-third of these for problems of their own. About half these percentages, mostly women, have attended Al-Anon. Of the same population, 13.3% indicate ever attending a 12-step meeting (including non-alcohol-oriented groups), 5.3% in the last year. During the prior year a further 2.1% used other support/therapy groups and 5.5% sought individual counselling/therapy for personal problems other than alcohol. In contrast to this high reported utilization, only 4.9% (ever) and 2.3% (12-months) reported going to anyone including AA for a problem (of their own) related to drinking.

  17. Medical Relabeling in Gamblers Anonymous: The Construction of an Ideal Member.

    Science.gov (United States)

    Turner, David N.; Saunders, Danny

    1990-01-01

    Observed 2 Gamblers Anonymous (GA) groups in South Wales over a 12-month period. Determined 2 broad consequences arose from encountering fellow sufferers: acceptance of diagnosis and commitment to recovery and to will of GA, or rejection of the diagnosis with the knowledge that they are returning to the outside world with a reconstituted…

  18. A globally optimal k-anonymity method for the de-identification of health data.

    Science.gov (United States)

    El Emam, Khaled; Dankar, Fida Kamal; Issa, Romeo; Jonker, Elizabeth; Amyot, Daniel; Cogo, Elise; Corriveau, Jean-Pierre; Walker, Mark; Chowdhury, Sadrul; Vaillancourt, Regis; Roffey, Tyson; Bottomley, Jim

    2009-01-01

    Explicit patient consent requirements in privacy laws can have a negative impact on health research, leading to selection bias and reduced recruitment. Often legislative requirements to obtain consent are waived if the information collected or disclosed is de-identified. The authors developed and empirically evaluated a new globally optimal de-identification algorithm that satisfies the k-anonymity criterion and that is suitable for health datasets. Authors compared OLA (Optimal Lattice Anonymization) empirically to three existing k-anonymity algorithms, Datafly, Samarati, and Incognito, on six public, hospital, and registry datasets for different values of k and suppression limits. Measurement Three information loss metrics were used for the comparison: precision, discernability metric, and non-uniform entropy. Each algorithm's performance speed was also evaluated. The Datafly and Samarati algorithms had higher information loss than OLA and Incognito; OLA was consistently faster than Incognito in finding the globally optimal de-identification solution. For the de-identification of health datasets, OLA is an improvement on existing k-anonymity algorithms in terms of information loss and performance.

  19. A context-sensitive approach to anonymizing spatial surveillance data: impact on outbreak detection.

    Science.gov (United States)

    Cassa, Christopher A; Grannis, Shaun J; Overhage, J Marc; Mandl, Kenneth D

    2006-01-01

    The use of spatially based methods and algorithms in epidemiology and surveillance presents privacy challenges for researchers and public health agencies. We describe a novel method for anonymizing individuals in public health data sets by transposing their spatial locations through a process informed by the underlying population density. Further, we measure the impact of the skew on detection of spatial clustering as measured by a spatial scanning statistic. Cases were emergency department (ED) visits for respiratory illness. Baseline ED visit data were injected with artificially created clusters ranging in magnitude, shape, and location. The geocoded locations were then transformed using a de-identification algorithm that accounts for the local underlying population density. A total of 12,600 separate weeks of case data with artificially created clusters were combined with control data and the impact on detection of spatial clustering identified by a spatial scan statistic was measured. The anonymization algorithm produced an expected skew of cases that resulted in high values of data set k-anonymity. De-identification that moves points an average distance of 0.25 km lowers the spatial cluster detection sensitivity by less than 4% and lowers the detection specificity less than 1%. A population-density-based Gaussian spatial blurring markedly decreases the ability to identify individuals in a data set while only slightly decreasing the performance of a standardly used outbreak detection tool. These findings suggest new approaches to anonymizing data for spatial epidemiology and surveillance.

  20. HOP: Achieving Efficient Anonymity in MANETs by Combining HIP, OLSR, and Pseudonyms

    Directory of Open Access Journals (Sweden)

    Campos Javier

    2011-01-01

    Full Text Available Offering secure and anonymous communications in mobile ad hoc networking environments is essential to achieve confidence and privacy, thus promoting widespread adoption of this kind of networks. In addition, some minimum performance levels must be achieved for any solution to be practical and become widely adopted. In this paper, we propose and implement HOP, a novel solution based on cryptographic Host Identity Protocol (HIP that offers security and user-level anonymity in MANET environments while maintaining good performance levels. In particular, we introduce enhancements to the authentication process to achieve Host Identity Tag (HIT relationship anonymity, along with source/destination HIT anonymity when combined with multihoming. Afterward we detail how we integrate our improved version of HIP with the OLSR routing protocol to achieve efficient support for pseudonyms. We implemented our proposal in an experimental testbed, and the results obtained show that performance levels achieved are quite good, and that the integration with OLSR is achieved with a low overhead.

  1. Security Enhanced Anonymous Multiserver Authenticated Key Agreement Scheme Using Smart Cards and Biometrics

    Directory of Open Access Journals (Sweden)

    Younsung Choi

    2014-01-01

    Full Text Available An anonymous user authentication scheme allows a user, who wants to access a remote application server, to achieve mutual authentication and session key establishment with the server in an anonymous manner. To enhance the security of such authentication schemes, recent researches combined user’s biometrics with a password. However, these authentication schemes are designed for single server environment. So when a user wants to access different application servers, the user has to register many times. To solve this problem, Chuang and Chen proposed an anonymous multiserver authenticated key agreement scheme using smart cards together with passwords and biometrics. Chuang and Chen claimed that their scheme not only supports multiple servers but also achieves various security requirements. However, we show that this scheme is vulnerable to a masquerade attack, a smart card attack, a user impersonation attack, and a DoS attack and does not achieve perfect forward secrecy. We also propose a security enhanced anonymous multiserver authenticated key agreement scheme which addresses all the weaknesses identified in Chuang and Chen’s scheme.

  2. Security enhanced anonymous multiserver authenticated key agreement scheme using smart cards and biometrics.

    Science.gov (United States)

    Choi, Younsung; Nam, Junghyun; Lee, Donghoon; Kim, Jiye; Jung, Jaewook; Won, Dongho

    2014-01-01

    An anonymous user authentication scheme allows a user, who wants to access a remote application server, to achieve mutual authentication and session key establishment with the server in an anonymous manner. To enhance the security of such authentication schemes, recent researches combined user's biometrics with a password. However, these authentication schemes are designed for single server environment. So when a user wants to access different application servers, the user has to register many times. To solve this problem, Chuang and Chen proposed an anonymous multiserver authenticated key agreement scheme using smart cards together with passwords and biometrics. Chuang and Chen claimed that their scheme not only supports multiple servers but also achieves various security requirements. However, we show that this scheme is vulnerable to a masquerade attack, a smart card attack, a user impersonation attack, and a DoS attack and does not achieve perfect forward secrecy. We also propose a security enhanced anonymous multiserver authenticated key agreement scheme which addresses all the weaknesses identified in Chuang and Chen's scheme.

  3. A Quantitative Study on Anonymity and Professionalism within an Online Free Open Access Medical Education Community.

    Science.gov (United States)

    Dimitri, Daneilla; Gubert, Andrea; Miller, Amanda B; Thoma, Brent; Chan, Teresa

    2016-09-18

    The increasing use of social media to share knowledge in medical education has led to concerns about the professionalism of online medical learners and physicians. However, there is a lack of research on the behavior of professionals within open online discussions. In 2013, the Academic Life in Emergency Medicine website (ALiEM.com) launched a series of moderated online case discussions that provided an opportunity to explore the relationship between anonymity and professionalism. Comments from 12 case discussions conducted over a one-year period were analyzed using modified scales of anonymity and professionalism derived by Kilner and Hoadley. Descriptive statistics and Spearman calculations were conducted for the professionalism score, anonymity score, and level of participation. No correlation was found between professionalism and anonymity scores (rho = -0.004, p = 0.97). However, the number of comments (rho = 0.35, p professional environment through the use of a website with a positive reputation, the modelling of respectful behaviour by the moderators, the norms of the broader online community, and the pre-specified objectives for each discussion.

  4. Open and Anonymous Peer Review in a Digital Online Environment Compared in Academic Writing Context

    Science.gov (United States)

    Razi, Salim

    2016-01-01

    This study compares the impact of "open" and "anonymous" peer feedback as an adjunct to teacher-mediated feedback in a digital online environment utilising data gathered on an academic writing course at a Turkish university. Students were divided into two groups with similar writing proficiencies. Students peer reviewed papers…

  5. Brother-Sister Incest: Data from Anonymous Computer-Assisted Self Interviews

    Science.gov (United States)

    Stroebel, Sandra S.; O'Keefe, Stephen L.; Beard, Keith W.; Kuo, Shih-Ya; Swindell, Samuel; Stroupe, Walter

    2013-01-01

    Retrospective data were entered anonymously by 1,521 adult women using computer-assisted self interview. Forty were classified as victims of brother-sister incest, 19 were classified as victims of father-daughter incest, and 232 were classified as victims of sexual abuse by an adult other than their father before reaching 18 years of age. The…

  6. Peer Feedback in Anonymous Peer Review in an EFL Writing Class in Spain

    Science.gov (United States)

    Coté, Robert A.

    2014-01-01

    The present study reports the results of a process of peer feedback through anonymous peer review in an EFL writing class. Numerous studies have reported on the benefits of peer review (PR) in the ESL/EFL writing classroom. However, the literature also identifies social issues that can negatively affect the outcome of face-to-face PR. In this…

  7. Romantic Relationship Advice from Anonymous Online Helpers: The Peer Support Adolescents Exchange

    Science.gov (United States)

    Kim, Jung-Eun; Weinstein, Emily C.; Selman, Robert L.

    2017-01-01

    This empirical study investigates adolescents' responses to peers' personal accounts of romantic relationship difficulties posted to an online forum. We analyze 440 anonymous responses to personal accounts of four romantic relationship issues: controlling partners, break-ups, trust issues, and partner cruelty. Responses were categorized, in order…

  8. Single nucleotide polymorphisms and indel markers from the transcriptome of garlic

    Science.gov (United States)

    Garlic (Allium sativum L.) is cultivated world-wide and widely appreciated for its culinary uses. In spite of primarily being asexually propagated, garlic shows great diversity for adaptation to diverse production environments and bulb phenotypes. Anonymous molecular markers have been used to assess...

  9. Alcoholics Anonymous

    Science.gov (United States)

    ... China Colombia Costa Rica Cuba Cyprus Czech Republic Denmark Dominican Republic Ecuador Egypt El Salvador Estonia Faroe ... Make a contribution | Self-Support Press/Media | Archives & History | A.A. General Service Board Calendar | G.S.O. ...

  10. New microsatellite markers classifying nontoxic and toxic Jatropha ...

    Indian Academy of Sciences (India)

    sions of jatropha from India and a nontoxic accession from. Mexico. Basha and Sujatha (2009) reported genetic vari- ation and interspecific hybrids of Jatropha species using. RAPD and ISSR as nuclear specific markers, and chloro- plast microsatellite markers as organelle specific markers. Ganesh et al. (2008) studied ...

  11. Comparison of two methods for measuring γ-H2AX nuclear fluorescence as a marker of DNA damage in cultured human cells: applications for microbeam radiation therapy

    Science.gov (United States)

    Anderson, D.; Andrais, B.; Mirzayans, R.; Siegbahn, E. A.; Fallone, B. G.; Warkentin, B.

    2013-06-01

    Microbeam radiation therapy (MRT) delivers single fractions of very high doses of synchrotron x-rays using arrays of microbeams. In animal experiments, MRT has achieved higher tumour control and less normal tissue toxicity compared to single-fraction broad beam irradiations of much lower dose. The mechanism behind the normal tissue sparing of MRT has yet to be fully explained. An accurate method for evaluating DNA damage, such as the γ-H2AX immunofluorescence assay, will be important for understanding the role of cellular communication in the radiobiological response of normal and cancerous cell types to MRT. We compare two methods of quantifying γ-H2AX nuclear fluorescence for uniformly irradiated cell cultures: manual counting of γ-H2AX foci by eye, and an automated, MATLAB-based fluorescence intensity measurement. We also demonstrate the automated analysis of cell cultures irradiated with an array of microbeams. In addition to offering a relatively high dynamic range of γ-H2AX signal versus irradiation dose ( > 10 Gy), our automated method provides speed, robustness, and objectivity when examining a series of images. Our in-house analysis facilitates the automated extraction of the spatial distribution of the γ-H2AX intensity with respect to the microbeam array — for example, the intensities in the peak (high dose area) and valley (area between two microbeams) regions. The automated analysis is particularly beneficial when processing a large number of samples, as is needed to systematically study the relationship between the numerous dosimetric and geometric parameters involved with MRT (e.g., microbeam width, microbeam spacing, microbeam array dimensions, peak dose, valley dose, and geometric arrangement of multiple arrays) and the resulting DNA damage.

  12. Adolescent Substance Abuse in Mexico, Puerto Rico and The United States: Effect of Anonymous versus Confidential Survey Formats

    Science.gov (United States)

    Latimer, William W.; O'Brien, Megan S.; Vasquez, Marco A.; Medina-Mora, Maria Elena; Rios-Bedoya, Carlos F.; Floyd, Leah J.

    2006-01-01

    Anonymous surveys have been widely used worldwide to describe adolescent substance use yet cannot elucidate causal drug abuse predictors. Studies in the U.S. have generally found that anonymous and confidential surveys yield comparable levels of self-reported substance use, yet the effect of survey format on youth self-report has not been…

  13. Emergence of Informal Educative Space out of an Anonymous Online Bulletin Board in Korea during the Global Economic Crisis

    Science.gov (United States)

    Kang, Dae Joong; Choi, Seon Joo; Lee, SeungHyeop

    2013-01-01

    This study aimed to understand how people learn and teach informally in an anonymous online bulletin board, the primary purpose of which is not learning and teaching. We conducted a qualitative analysis of comments and replies tagged to the most popular postings of an anonymous online bulletin board, during the global economic crisis in 2008-2009.…

  14. Three-factor anonymous authentication and key agreement scheme for Telecare Medicine Information Systems.

    Science.gov (United States)

    Arshad, Hamed; Nikooghadam, Morteza

    2014-12-01

    Nowadays, with comprehensive employment of the internet, healthcare delivery services is provided remotely by telecare medicine information systems (TMISs). A secure mechanism for authentication and key agreement is one of the most important security requirements for TMISs. Recently, Tan proposed a user anonymity preserving three-factor authentication scheme for TMIS. The present paper shows that Tan's scheme is vulnerable to replay attacks and Denial-of-Service attacks. In order to overcome these security flaws, a new and efficient three-factor anonymous authentication and key agreement scheme for TMIS is proposed. Security and performance analysis shows superiority of the proposed scheme in comparison with previously proposed schemes that are related to security of TMISs.

  15. THE WIKILEAKS´S CASE AND ANONYMITY: EFFECTS ON THE INFORMATION FREEDOM

    Directory of Open Access Journals (Sweden)

    Marlus Heriberto Arns de Oliveira

    2015-10-01

    Full Text Available The Constitution of the Federative Republic of Brazil, enacted in 1988 during the democratization process of the country after the end of an authoritarian regime preceded by several others that show a non-democratic tradition in the Brazilian Republic, remained still remnants an authoritarian Patronizing and Paternalist state, the example of the final part of the Article 5, item IV, which claims to be the free expression of thought, but forbids anonymity, prohibition which deserves to be rethought, especially on the internet, where the navigation data of people deserve protection, as well as their rights to remain anonymous, a fact which entails the need for reflection on the scope and how best to interpret the constitutional provision cited, a debate that, in the proposed article will deal think the ideas of paternalism, authoritarianism and freedom, whose focus will be about within the Internet, social networks and the Knowledge Society.

  16. An efficient anonymous authentication scheme for wireless body area networks using elliptic curve cryptosystem.

    Science.gov (United States)

    Zhao, Zhenguo

    2014-02-01

    With the development of wireless networks and medical sensors, wireless body area networks are playing more and more important role in the field of healthcare service. The data transmitted in WBANs is very sensitive since it will be used in clinical diagnoses or measurements. Therefore, security and privacy of communication in WBANs derive increasing attentions from the academia and industry. In this paper, we propose an identity (ID)-based efficient anonymous authentication scheme for WBANs using elliptic curve cryptosystem (ECC). Due to the ID-based concept, there is no certificate is needed in the proposed scheme. Moreover, the proposed scheme not only provides mutual authentication between the client and the application provider but also provides client anonymity. Performance analysis shows that improvements of 50.58% and 3.87% in the client side and the application provider side separately. Then the proposed scheme is more suitable for WBANs.

  17. Anonymous three-party password-authenticated key exchange scheme for Telecare Medical Information Systems.

    Science.gov (United States)

    Xie, Qi; Hu, Bin; Dong, Na; Wong, Duncan S

    2014-01-01

    Telecare Medical Information Systems (TMIS) provide an effective way to enhance the medical process between doctors, nurses and patients. For enhancing the security and privacy of TMIS, it is important while challenging to enhance the TMIS so that a patient and a doctor can perform mutual authentication and session key establishment using a third-party medical server while the privacy of the patient can be ensured. In this paper, we propose an anonymous three-party password-authenticated key exchange (3PAKE) protocol for TMIS. The protocol is based on the efficient elliptic curve cryptosystem. For security, we apply the pi calculus based formal verification tool ProVerif to show that our 3PAKE protocol for TMIS can provide anonymity for patient and doctor while at the same time achieves mutual authentication and session key security. The proposed scheme is secure and efficient, and can be used in TMIS.

  18. A Semantic-Based K-Anonymity Scheme for Health Record Linkage.

    Science.gov (United States)

    Lu, Yang; Sinnott, Richard O; Verspoor, Karin

    2017-01-01

    Record linkage is a technique for integrating data from sources or providers where direct access to the data is not possible due to security and privacy considerations. This is a very common scenario for medical data, as patient privacy is a significant concern. To avoid privacy leakage, researchers have adopted k-anonymity to protect raw data from re-identification however they cannot avoid associated information loss, e.g. due to generalisation. Given that individual-level data is often not disclosed in the linkage cases, but yet remains potentially re-discoverable, we propose semantic-based linkage k-anonymity to de-identify record linkage with fewer generalisations and eliminate inference disclosure through semantic reasoning.

  19. A Framework For Enhancing Privacy In Location Based Services Using K-Anonymity Model

    Directory of Open Access Journals (Sweden)

    Jane Mugi

    2015-08-01

    Full Text Available Abstract This paper presents a framework for enhancing privacy in Location Based Services using K-anonymity model. Users of location based services have to reveal their location information in order to use these services however this has threatened the user privacy. K-anonymity approach has been studied extensively in various forms. However it is only effective when the user location is fixed. When a user moves and continuously sends their location information the location service provider can approximate user trajectory which poses a threat to the trajectory privacy of the user. This framework will ensure that user privacy is enhanced for both snapshot and continuous queries. The efficiency and effectiveness of the proposed framework was evaluated the results indicate that the proposed framework has high success rate and good run time performance.

  20. Applying LU Decomposition of Matrices to Design Anonymity Bilateral Remote User Authentication Scheme

    Directory of Open Access Journals (Sweden)

    Xiong Li

    2013-01-01

    Full Text Available We apply LU decomposition of matrices to present an anonymous bilateral authentication scheme. This paper aims at improving security and providing more excellent performances for remote user authentication scheme. The proposed scheme can provide bilateral authentication and session key agreement, can quickly check the validity of the input password, and can really protect the user anonymity. The security of the proposed scheme is based on the discrete logarithm problem (DLP, Diffie-Hellman problem (DHP, and the one-way hash function. It can resist various attacks such as insider attack, impersonation attack, server spoofing attack, and stolen smart card attack. Moreover, the presented scheme is computationally efficient for real-life implementation.

  1. Anonymous three-party password-authenticated key exchange scheme for Telecare Medical Information Systems.

    Directory of Open Access Journals (Sweden)

    Qi Xie

    Full Text Available Telecare Medical Information Systems (TMIS provide an effective way to enhance the medical process between doctors, nurses and patients. For enhancing the security and privacy of TMIS, it is important while challenging to enhance the TMIS so that a patient and a doctor can perform mutual authentication and session key establishment using a third-party medical server while the privacy of the patient can be ensured. In this paper, we propose an anonymous three-party password-authenticated key exchange (3PAKE protocol for TMIS. The protocol is based on the efficient elliptic curve cryptosystem. For security, we apply the pi calculus based formal verification tool ProVerif to show that our 3PAKE protocol for TMIS can provide anonymity for patient and doctor while at the same time achieves mutual authentication and session key security. The proposed scheme is secure and efficient, and can be used in TMIS.

  2. Practical m-k-Anonymization for Collaborative Data Publishing without Trusted Third Party

    Directory of Open Access Journals (Sweden)

    Jingyu Hua

    2017-01-01

    Full Text Available In collaborative data publishing (CDP, an m-adversary attack refers to a scenario where up to m malicious data providers collude to infer data records contributed by other providers. Existing solutions either rely on a trusted third party (TTP or introduce expensive computation and communication overheads. In this paper, we present a practical distributed k-anonymization scheme, m-k-anonymization, designed to defend against m-adversary attacks without relying on any TTPs. We then prove its security in the semihonest adversary model and demonstrate how an extension of the scheme can also be proven secure in a stronger adversary model. We also evaluate its efficiency using a commonly used dataset.

  3. Decision no 2010-DC-0189 by the Nuclear Safety Authority on the 7. of July 2010 specifying to Electricite de France-Societe Anonyme (EDF-SA) instructions related to modalities of water sampling and consumption, and of release in the environment of liquid and gaseous effluents for the operation of the Flamanville 1 (IBN n 108), Flamanville 2 (INB n 109) and Flamanville 3 (INB n 167) reactors

    International Nuclear Information System (INIS)

    2010-01-01

    After references to the different legal and official documents (codes, orders, minister's opinion, public surveys, administrative authorizations, local community opinion), this document specifies the instructions related to modalities of water sampling and consumption, and of release in the environment of liquid and gaseous effluents from three nuclear reactors. These instructions and provisions concern the general means implemented by the operator, records, the control by authorities, the limits of water sampling and consumption, the water sampling process, the sampling works and their maintenance and control, the release of liquid, gaseous and radioactive effluents, their control, the control of the environment (air, soil, surface and underground water, sampling point implantation), the information of authorities and of population

  4. Un algorithme probabiliste d'election et d'arbre couvrant sur des reseaux anonymes

    OpenAIRE

    Lavallee, Ivan; Lavault, C.

    1989-01-01

    Dans le present rapport, nous proposons deux variantes d'un algorithme distribue, probabiliste, asynchrone d'election et de construction d'arbre couvrant dans des reseaux anonymes a topologie quelconque. A notre connaissance, cet algorithme est le premier du genre, a etre totalement et rigoureusement specifie. Il est fonde sur un precedent algorithme deterministe d'election pour reseaux de processus a identites distinctes. Nous montrons ici comment construire les deux variantes, suivant deux ...

  5. Facebook’s Ugly Sisters: Anonymity and Abuse on Formspring and Ask.fm

    OpenAIRE

    Binns, Amy

    2013-01-01

    New question and answer websites Ask.fm and Formspring have brought highly specific and personal abuse to a new level amongst young people by providing easy anonymity to users within a circle of offline friendship groups culled from Facebook. Relatively unknown due to their unattractiveness to adults, these sites are growing rapidly and have already been associated with at least eight suicides amongst teenagers. \\ud \\ud Media educators at school level encouraging self-awareness of social medi...

  6. Nursing lives in the blogosphere: A thematic analysis of anonymous online nursing narratives.

    Science.gov (United States)

    Castro, Aimee; Andrews, Gavin

    2018-02-01

    The aim of this study was to explore the work-life narratives of nurses through a thematic analysis of the nursing accounts they post in their publicly accessible, anonymous blogs. Many nurses participate on social media. Blogs have been advocated as a self-reflective tool in nursing practice, yet as far as the authors are aware, no previous studies have explored nurses' individual blogs for their potential to reveal nurses' perceptions of nursing work. The research design was qualitative description. Between May-August 2015, Internet search engines were used to discover lists of nursing blogs recommended by organizations representing nurses' interests. Recommended blogs were purposively sampled. Four anonymous blogs written by nurses from different nursing specialties met the sampling criteria. All 520 of their entries from 2014 were read and copied into NVivo 10, where an inductive coding process was followed. Three major themes arose in these nurses' online discussions of their work lives: they truly care about and value their nursing work, but they are feeling stressed and burnt out and they are using their anonymous blogs to share factors that frustrate them in their nursing work. Three main areas of frustration were revealed: teamwork problems, challenging patients and families, and management issues. Anonymous nursing blogs offer valuable, longitudinal insights into nurses' perceptions of their work lives. Nursing blogs should be further explored for ongoing insights into nurses' experiences of nursing work, as well as nurses' recommendations for addressing issues causing them to feel frustrated in their work environments. © 2017 John Wiley & Sons Ltd.

  7. Use of anonymous Web communities and websites by medical consumers in Japan to research drug information.

    Science.gov (United States)

    Kishimoto, Keiko; Fukushima, Noriko

    2011-01-01

    In this study, we investigated the status of researching drug information online, and the type of Internet user who uses anonymous Web communities and websites. A Web-based cross-sectional survey of 10875 male and female Internet users aged 16 and over was conducted in March 2010. Of 10282 analyzed respondents, excluding medical professionals, about 47% reported that they had previously searched the Internet for drug information and had used online resources ranging from drug information search engines and pharmaceutical industry websites to social networking sites and Twitter. Respondents who had researched drug information online (n=4861) were analyzed by two multivariable logistic regressions. In Model 1, the use of anonymous websites associated with age (OR, 0.778; 95% CI, 0.742-0.816), referring to the reputation and the narrative of other Internet users on shopping (OR, 1.640; 95% CI, 1.450-1.855), taking a prescription drug (OR, 0.806; 95% CI, 0.705-0.922), and frequent consulting with non-professionals about medical care and health (OR, 1.613; 95% CI, 1.396-1.865). In Model 2, use of only anonymous websites was associated with age (OR, 0.753; 95% CI, 0.705-0.805), using the Internet daily (OR, 0.611; 95% CI, 0.462-0.808), taking a prescription drug (OR, 0.614; 95% CI, 0.505-0.747), and experience a side effect (OR, 0.526; 95% CI, 0.421-0.658). The analysis revealed the profiles of Internet users who researched drug information on social media sites where the information providers are anonymous and do not necessarily have adequate knowledge of medicine and online information literacy.

  8. Gamblers Anonymous in Israel: a participant observation study of a self-help group.

    Science.gov (United States)

    Cromer, G

    1978-10-01

    This participant observation study of the first Gamblers Anonymous group in Israel is designed to show (1) the ways in which the group helps it members rehabilitate themselves, (2) the three stages through which they must go in order to ensure success, and (3) the reason why some participants fail to do so. The article concludes with a number of observations concerning the extent of gambling in Israel and the different ways that should be developed for dealing with the problem.

  9. [Examination of the Young maladaptive schemes in a group of Gamblers Anonymous].

    Science.gov (United States)

    Katona, Zsuzsa; Körmendi, Attila

    2012-01-01

    Literature of gambling addiction has become widespread in last years. Many studies were written about the vulnerability factors helping the development of addiction, theoretical models, comorbid problems and therapy possibilities. Currently there is no integrated theoretical model that could explain sufficiently the development and maintenance of pathological gambling. The treatment issue is also unresolved. Cognitive psychology is a dynamically developing field of psychology and good results are achieved in gambling treatment with applying cognitive techniques. Jeffrey Young's schema-focused therapy is a recent theoretical and therapeutic direction within cognitive psychology which emphasizes the necessity of emotional changes beside rational ones in the interest of efficiency. The purpose of our research is to examine and analyse active maladaptive schemas among gamblers who are members of Gamblers Anonymous self-help group. 23 control persons and 23 gamblers associated with support group of Gamblers Anonymous took part in our research. The severity of gambling behaviour was measured by Gamblers Anonymous Twenty Questions. For exploring maladaptive schemas we used the shorter 114-item version of the Young Schema Questionnaire (YSQ-S3). All the examined gamblers were considered as problem gamblers based on Gamblers Anonymous Twenty Questions. In the control group there where no active schemas while in the group of gamblers several schemas (Emotional deprivation, Self-sacrifice, Recognition seeking, Emotional inhibition, Unrelenting standards, Self-punitiveness, Insufficient self-control) showed activity. Active schemas show similarity in their matter with main establishments of researches about gamblers and support the role of impulsivity, narcissistic traits, self-medicalization and emotional deprivation in the development and maintenance of pathological gambling.

  10. Mirroring the videos of Anonymous:cloud activism, living networks, and political mimesis

    OpenAIRE

    Fish, Adam Richard

    2016-01-01

    Mirrors describe the multiplication of data across a network. In this article, I examine the politics of mirroring as practiced on videos by the hacktivist network Anonymous. Mirrors are designed to retain visibility on social media platforms and motivate viewers towards activism. They emerge from a particular social structure and propagate a specific symbolic system. Furthermore, mirrors are not exact replicas nor postmodern representations. Rather, mirroring maps a contestation over visibil...

  11. Mutual support and recovery in the Russian Alcoholics Anonymous online community

    Directory of Open Access Journals (Sweden)

    Lyytikäinen Laura

    2016-04-01

    Full Text Available AIMS – In Russia the paradigm of alcoholism as a disease is still in contrast to the general perception of alcoholics as weak-willed. This article studies alcoholism and recovery in Russia through the case study of the Russian Alcoholics Anonymous online group. It studies how people who are seeking help for their drinking problems in this online community come to incorporate a new self-understanding of being ill with alcoholism.

  12. Anonymous As a Cyber Tribe: A New Model for Complex, Non-State Cyber Actors

    Science.gov (United States)

    2015-05-01

    non- state cyber actors. The Air Force values a professional workplace that strictly prohibits racism , sexism, lewd material, and most forms of...AU/ACSC/LIDOWSKI, R/AY15 AIR COMMAND AND STAFF COLLEGE AIR UNIVERSITY ANONYMOUS AS A CYBER TRIBE: A NEW MODEL FOR COMPLEX, NON- STATE ...government or the Department of Defense. In accordance with Air Force Instruction 51-303, it is not copyrighted, but is the property of the United

  13. Local and global recoding methods for anonymizing set-valued data

    KAUST Repository

    Terrovitis, Manolis

    2010-06-10

    In this paper, we study the problem of protecting privacy in the publication of set-valued data. Consider a collection of supermarket transactions that contains detailed information about items bought together by individuals. Even after removing all personal characteristics of the buyer, which can serve as links to his identity, the publication of such data is still subject to privacy attacks from adversaries who have partial knowledge about the set. Unlike most previous works, we do not distinguish data as sensitive and non-sensitive, but we consider them both as potential quasi-identifiers and potential sensitive data, depending on the knowledge of the adversary. We define a new version of the k-anonymity guarantee, the k m-anonymity, to limit the effects of the data dimensionality, and we propose efficient algorithms to transform the database. Our anonymization model relies on generalization instead of suppression, which is the most common practice in related works on such data. We develop an algorithm that finds the optimal solution, however, at a high cost that makes it inapplicable for large, realistic problems. Then, we propose a greedy heuristic, which performs generalizations in an Apriori, level-wise fashion. The heuristic scales much better and in most of the cases finds a solution close to the optimal. Finally, we investigate the application of techniques that partition the database and perform anonymization locally, aiming at the reduction of the memory consumption and further scalability. A thorough experimental evaluation with real datasets shows that a vertical partitioning approach achieves excellent results in practice. © 2010 Springer-Verlag.

  14. There is no ``I'' in referee: Why referees should be anonymous

    Science.gov (United States)

    Ucko, Daniel

    2015-03-01

    From the early days of modern science, it has been recognized that scientific claims must be verified by someone who is not the maker of those claims, and who furthermore has no stake in the matter. In other words, claims need to be evaluated objectively, by the community. The way in which this tends to be done is by peer review conducted by journals. Peer review as currently practiced touches on the themes of trust, where the trust is in institutions and procedures that emerge from expert communities. The practice of peer review is viewed as a citizenly duty of scientists in the scientific community, because all scientists take turns serving either as authors, referees, and editors in the peer review process We lack the resources to have a work evaluated by the entire community, so we substitute with a representative. Yet, in most examples of scientific review, the referee or referees are anonymous. This question is particularly important when the peer review process is brought to bear in order to evaluate matters beyond scientific validity, more ``subjective'' criteria such as relative importance, broadness of interest - criteria that do not appear to have an objective standard of comparison and validation. I will show that the anonymity of referees, far from endangering this trust, actually strengthens it. I will show that this anonymity is crucial in order to maintain any objectivity in scientific peer review, and why authors should not try to unmask the referee. Also at American Physical Society (APS).

  15. Provably Secure Anonymous-yet-Accountable Crowdsensing with Scalable Sublinear Revocation

    Directory of Open Access Journals (Sweden)

    Rahaman Sazzadur

    2017-10-01

    Full Text Available Group signature schemes enable anonymous-yet-accountable communications. Such a capability is extremely useful for applications, such as smartphone-based crowdsensing and citizen science. However, the performance of modern group signature schemes is still inadequate to manage large dynamic groups. In this paper, we design the first provably secure verifier-local revocation (VLR - based group signature scheme that supports sublinear revocation, named Sublinear Revocation with Backward unlinkability and Exculpability (SRBE. To achieve this performance gain, SRBE introduces time bound pseudonyms for the signer. By introducing low-cost short-lived pseudonyms with sublinear revocation checking, SRBE drastically improves the efficiency of the group-signature primitive. The backward-unlinkable anonymity of SRBE guarantees that even after the revocation of a signer, her previously generated signatures remain unlinkable across epochs. This behavior favors the dynamic nature of real-world crowdsensing settings. We prove its security and discuss parameters that influence its scalability. Using SRBE, we also implement a prototype named GroupSense for anonymous-yet-accountable crowdsensing, where our experimental findings confirm GroupSense’s scalability. We point out the open problems remaining in this space.

  16. kACTUS 2: Privacy Preserving in Classification Tasks Using k-Anonymity

    Science.gov (United States)

    Kisilevich, Slava; Elovici, Yuval; Shapira, Bracha; Rokach, Lior

    k-anonymity is the method used for masking sensitive data which successfully solves the problem of re-linking of data with an external source and makes it difficult to re-identify the individual. Thus k-anonymity works on a set of quasi-identifiers (public sensitive attributes), whose possible availability and linking is anticipated from external dataset, and demands that the released dataset will contain at least k records for every possible quasi-identifier value. Another aspect of k is its capability of maintaining the truthfulness of the released data (unlike other existing methods). This is achieved by generalization, a primary technique in k-anonymity. Generalization consists of generalizing attribute values and substituting them with semantically consistent but less precise values. When the substituted value doesn’t preserve semantic validity the technique is called suppression which is a private case of generalization. We present a hybrid approach called compensation which is based on suppression and swapping for achieving privacy. Since swapping decreases the truthfulness of attribute values there is a tradeoff between level of swapping (information truthfulness) and suppression (information loss) incorporated in our algorithm.

  17. Potential harms, anonymization, and the right to withdraw consent to biobank research.

    Science.gov (United States)

    Eriksson, Stefan; Helgesson, Gert

    2005-09-01

    This paper discusses the potential harms involved in biobank research and how ethical review, informed consent, withdrawals, and anonymization of samples should be handled in the light of these harms. There is less risk involved in biobank research than in human subject research; it should therefore be treated differently. In our view, anonymization should not be an automatically permissible response to requests for withdrawal. Nor should a request for withdrawal necessarily stop research on identifiable samples. Apart from not being particularly appropriate for protecting the interests of individuals, anonymization of samples has a negative impact on research. We suggest that the current view on withdrawal from research, supported by the Declaration of Helsinki and subsequent ethical guidelines, be abandoned in the context of biobank research and be replaced by an approach inspired by the Nuremberg Code. This approach requires those wishing to withdraw their samples from research to present sufficient reason for doing so. Our interpretation of 'sufficient reason' includes all those involving genuine, deeply felt concerns that are not based on misconceptions. Still, this underlines the fact that we all share a responsibility for health research and that no one should take withdrawal from biobank research lightly.

  18. Does the type of anonymity matter? The impact of visualization on information sharing in online groups.

    Science.gov (United States)

    Wodzicki, Katrin; Schwämmlein, Eva; Cress, Ulrike; Kimmerle, Joachim

    2011-03-01

    Groups who share information in computer-mediated settings often have to deal with the issue of anonymity. Previous research has shown that only people with a prosocial orientation--that is, those whose main interest is to add to the benefit of the group as a whole--are willing to share information in anonymous situations. The willingness to share information by those people with a proself orientation--that is, those who put more emphasis on their personal benefit--can be increased by providing photographs of the other group members. The information-sharing behavior of prosocials, however, suffers from such a deletion of anonymity. In an online experiment, we examined how information-sharing behavior of proselfs may be increased without negatively influencing the information-sharing behavior of prosocials in an online setting. It was shown that even proselfs share information if the group members are visualized in a homogeneous way, while prosocials' information-sharing behavior is not impaired by this visualization. In addition, the results suggest that people's perceived homogeneity of the online group, as well as the importance of the collective goal, are the underlying processes of this effect. These results have important practical implications for the design of online information-sharing settings.

  19. Fortified Anonymous Communication Protocol for Location Privacy in WSN: A Modular Approach

    Directory of Open Access Journals (Sweden)

    Abdel-Shakour Abuzneid

    2015-03-01

    Full Text Available Wireless sensor network (WSN consists of many hosts called sensors. These sensors can sense a phenomenon (motion, temperature, humidity, average, max, min, etc. and represent what they sense in a form of data. There are many applications for WSNs including object tracking and monitoring where in most of the cases these objects need protection. In these applications, data privacy itself might not be as important as the privacy of source location. In addition to the source location privacy, sink location privacy should also be provided. Providing an efficient end-to-end privacy solution would be a challenging task to achieve due to the open nature of the WSN. The key schemes needed for end-to-end location privacy are anonymity, observability, capture likelihood, and safety period. We extend this work to allow for countermeasures against multi-local and global adversaries. We present a network model protected against a sophisticated threat model: passive /active and local/multi-local/global attacks. This work provides a solution for end-to-end anonymity and location privacy as well. We will introduce a framework called fortified anonymous communication (FAC protocol for WSN.

  20. The long path to pregnancy: early experience with dual anonymous gamete donation in a European in vitro fertilisation referral centre

    Directory of Open Access Journals (Sweden)

    Sills Eric

    2010-08-01

    Full Text Available Abstract Background This investigation describes features of patients undergoing in vitro fertilisation (IVF and embryo transfer (ET where both gametes were obtained from anonymous donors. Methods Gamete unsuitability or loss was confirmed in both members of seven otherwise healthy couples presenting for reproductive endocrinology consultation over a 12-month interval in Ireland. IVF was undertaken with fresh oocytes provided by anonymous donors in Ukraine; frozen sperm (anonymous donor was obtained from a licensed tissue establishment. For recipients, saline-enhanced sonography was used to assess intrauterine contour with endometrial preparation via transdermal estrogen. Results Among commissioning couples, mean±SD female and male age was 41.9 ± 3.7 and 44.6 ± 3.5 yrs, respectively. During this period, female age for non dual anonymous gamete donation IVF patients was 37.9 ± 3 yrs (p Conclusions Mean age of females undergoing dual anonymous donor gamete donation with IVF is significantly higher than the background IVF patient population. Even when neither partner is able to contribute any gametes for IVF, the clinical pregnancy rate per transfer can be satisfactory if both anonymous egg and sperm donation are used concurrently. Our report emphasises the role of pre-treatment counselling in dual anonymous gamete donation, and presents a coordinated screening and treatment approach in IVF where this option may be contemplated.

  1. (a,k)-Anonymous Scheme for Privacy-Preserving Data Collection in IoT-based Healthcare Services Systems.

    Science.gov (United States)

    Li, Hongtao; Guo, Feng; Zhang, Wenyin; Wang, Jie; Xing, Jinsheng

    2018-02-14

    The widely use of IoT technologies in healthcare services has pushed forward medical intelligence level of services. However, it also brings potential privacy threat to the data collection. In healthcare services system, health and medical data that contains privacy information are often transmitted among networks, and such privacy information should be protected. Therefore, there is a need for privacy-preserving data collection (PPDC) scheme to protect clients (patients) data. We adopt (a,k)-anonymity model as privacy pretection scheme for data collection, and propose a novel anonymity-based PPDC method for healthcare services in this paper. The threat model is analyzed in the client-server-to-user (CS2U) model. On client-side, we utilize (a,k)-anonymity notion to generate anonymous tuples which can resist possible attack, and adopt a bottom-up clustering method to create clusters that satisfy a base privacy level of (a 1 ,k 1 )-anonymity. On server-side, we reduce the communication cost through generalization technology, and compress (a 1 ,k 1 )-anonymous data through an UPGMA-based cluster combination method to make the data meet the deeper level of privacy (a 2 ,k 2 )-anonymity (a 1  ≥ a 2 , k 2  ≥ k 1 ). Theoretical analysis and experimental results prove that our scheme is effective in privacy-preserving and data quality.

  2. Secure anonymous mutual authentication for star two-tier wireless body area networks.

    Science.gov (United States)

    Ibrahim, Maged Hamada; Kumari, Saru; Das, Ashok Kumar; Wazid, Mohammad; Odelu, Vanga

    2016-10-01

    Mutual authentication is a very important service that must be established between sensor nodes in wireless body area network (WBAN) to ensure the originality and integrity of the patient's data sent by sensors distributed on different parts of the body. However, mutual authentication service is not enough. An adversary can benefit from monitoring the traffic and knowing which sensor is in transmission of patient's data. Observing the traffic (even without disclosing the context) and knowing its origin, it can reveal to the adversary information about the patient's medical conditions. Therefore, anonymity of the communicating sensors is an important service as well. Few works have been conducted in the area of mutual authentication among sensor nodes in WBAN. However, none of them has considered anonymity among body sensor nodes. Up to our knowledge, our protocol is the first attempt to consider this service in a two-tier WBAN. We propose a new secure protocol to realize anonymous mutual authentication and confidential transmission for star two-tier WBAN topology. The proposed protocol uses simple cryptographic primitives. We prove the security of the proposed protocol using the widely-accepted Burrows-Abadi-Needham (BAN) logic, and also through rigorous informal security analysis. In addition, to demonstrate the practicality of our protocol, we evaluate it using NS-2 simulator. BAN logic and informal security analysis prove that our proposed protocol achieves the necessary security requirements and goals of an authentication service. The simulation results show the impact on the various network parameters, such as end-to-end delay and throughput. The nodes in the network require to store few hundred bits. Nodes require to perform very few hash invocations, which are computationally very efficient. The communication cost of the proposed protocol is few hundred bits in one round of communication. Due to the low computation cost, the energy consumed by the nodes is

  3. Anonymity as an Instructional Scaffold in Peer Assessment: Its Effects on Peer Feedback Quality and Evolution in Students' Perceptions about Peer Assessment Skills

    Science.gov (United States)

    Rotsaert, Tijs; Panadero, Ernesto; Schellens, Tammy

    2018-01-01

    Although previous research has indicated that providing anonymity is an effective way to create a safe peer assessment setting, continuously ensuring anonymity prevents students from experiencing genuine two-way interactive feedback dialogues. The present study investigated how installing a transitional approach from an anonymous to a…

  4. (In)visible Ghosts in the Machine and the Powers that Bind: The Relational Securitization of Anonymous

    DEFF Research Database (Denmark)

    Dunn Cavelty, Myriam; Jaeger, Mark Daniel

    2015-01-01

    This paper analyzes the formation and subsequent securitization of the digital protest movement Anonymous, highlighting the emergence of social antagonists from communication itself. In contrast to existing approaches that implicitly or explicitly conceptualize Othering (and securitization) as un...

  5. Feedback from recently returned veterans on an anonymous web-based brief alcohol intervention.

    Science.gov (United States)

    Lapham, Gwen T; Hawkins, Eric J; Chavez, Laura J; Achtmeyer, Carol E; Williams, Emily C; Thomas, Rachel M; Ludman, Evette J; Kypri, Kypros; Hunt, Stephen C; Bradley, Katharine A

    2012-08-28

    Veterans of Operation Enduring Freedom and Operation Iraqi Freedom (OEF/OIF) are at increased risk for alcohol misuse, and innovative methods are needed to improve their access to alcohol screening and brief interventions (SBI). This study adapted an electronic SBI (e-SBI) website shown to be efficacious in college students for OEF/OIF veterans and reported findings from interviews with OEF/OIF veterans about their impressions of the e-SBI. Outpatient veterans of OEF/OIF who drank ≥3 days in the past week were recruited from a US Department of Veterans Affairs (VA) Deployment Health Clinic waiting room. Veterans privately pretested the anonymous e-SBI then completed individual semistructured audio-recorded interviews. Their responses were analyzed using template analysis to explore domains identified a priori as well as emergent domains. During interviews, all nine OEF/OIF veterans (1 woman and 8 men) indicated they had received feedback for risky alcohol consumption. Participants generally liked the standard-drinks image, alcohol-related caloric and monetary feedback, and the website's brevity and anonymity (a priori domains). They also experienced challenges with portions of the e-SBI assessment and viewed feedback regarding alcohol risk and normative drinking as problematic, but described potential benefits derived from the e-SBI (emergent domains). The most appealing e-SBIs would ensure anonymity and provide personalized transparent feedback about alcohol-related risk, consideration of the context for drinking, strategies to reduce drinking, and additional resources for veterans with more severe alcohol misuse. Results of this qualitative exploratory study suggest e-SBI may be an acceptable strategy for increasing OEF/OIF veteran access to evidenced-based alcohol SBI.

  6. Blinded Anonymization: a method for evaluating cancer prevention programs under restrictive data protection regulations.

    Science.gov (United States)

    Bartholomäus, Sebastian; Hense, Hans Werner; Heidinger, Oliver

    2015-01-01

    Evaluating cancer prevention programs requires collecting and linking data on a case specific level from multiple sources of the healthcare system. Therefore, one has to comply with data protection regulations which are restrictive in Germany and will likely become stricter in Europe in general. To facilitate the mortality evaluation of the German mammography screening program, with more than 10 Million eligible women, we developed a method that does not require written individual consent and is compliant to existing privacy regulations. Our setup is composed of different data owners, a data collection center (DCC) and an evaluation center (EC). Each data owner uses a dedicated software that preprocesses plain-text personal identifiers (IDAT) and plaintext evaluation data (EDAT) in such a way that only irreversibly encrypted record assignment numbers (RAN) and pre-aggregated, reversibly encrypted EDAT are transmitted to the DCC. The DCC uses the RANs to perform a probabilistic record linkage which is based on an established and evaluated algorithm. For potentially identifying attributes within the EDAT ('quasi-identifiers'), we developed a novel process, named 'blinded anonymization'. It allows selecting a specific generalization from the pre-processed and encrypted attribute aggregations, to create a new data set with assured k-anonymity, without using any plain-text information. The anonymized data is transferred to the EC where the EDAT is decrypted and used for evaluation. Our concept was approved by German data protection authorities. We implemented a prototype and tested it with more than 1.5 Million simulated records, containing realistically distributed IDAT. The core processes worked well with regard to performance parameters. We created different generalizations and calculated the respective suppression rates. We discuss modalities, implications and limitations for large data sets in the cancer registry domain, as well as approaches for further

  7. An improved biometrics-based remote user authentication scheme with user anonymity.

    Science.gov (United States)

    Khan, Muhammad Khurram; Kumari, Saru

    2013-01-01

    The authors review the biometrics-based user authentication scheme proposed by An in 2012. The authors show that there exist loopholes in the scheme which are detrimental for its security. Therefore the authors propose an improved scheme eradicating the flaws of An's scheme. Then a detailed security analysis of the proposed scheme is presented followed by its efficiency comparison. The proposed scheme not only withstands security problems found in An's scheme but also provides some extra features with mere addition of only two hash operations. The proposed scheme allows user to freely change his password and also provides user anonymity with untraceability.

  8. Applying Semigroup Property of Enhanced Chebyshev Polynomials to Anonymous Authentication Protocol

    Directory of Open Access Journals (Sweden)

    Hong Lai

    2012-01-01

    Full Text Available We apply semigroup property of enhanced Chebyshev polynomials to present an anonymous authentication protocol. This paper aims at improving security and reducing computational and storage overhead. The proposed scheme not only has much lower computational complexity and cost in the initialization phase but also allows the users to choose their passwords freely. Moreover, it can provide revocation of lost or stolen smart card, which can resist man-in-the-middle attack and off-line dictionary attack together with various known attacks.

  9. An Improved Biometrics-Based Remote User Authentication Scheme with User Anonymity

    Directory of Open Access Journals (Sweden)

    Muhammad Khurram Khan

    2013-01-01

    Full Text Available The authors review the biometrics-based user authentication scheme proposed by An in 2012. The authors show that there exist loopholes in the scheme which are detrimental for its security. Therefore the authors propose an improved scheme eradicating the flaws of An’s scheme. Then a detailed security analysis of the proposed scheme is presented followed by its efficiency comparison. The proposed scheme not only withstands security problems found in An’s scheme but also provides some extra features with mere addition of only two hash operations. The proposed scheme allows user to freely change his password and also provides user anonymity with untraceability.

  10. Sexual practices among men attending an anonymous HIV testing site in Singapore.

    Science.gov (United States)

    Bishop, G D; Kok, A J; Chan, R K

    1998-06-01

    This study was undertaken to provide an empirical basis for planning safer sex interventions in Singapore by examining the sexual practices of men attending an anonymous HIV testing site. All male clients attending the testing site from January, 1996 to January 1997 were asked to complete an anonymous questionnaire concerning oral and anal sex with men as well as vaginal, oral and anal sex with women within the past year. Questionnaires were obtained from 251 male clients, ranging in age from 17 to 70 years (mean = 30.3). Of these 50.6% reported sex with women only, 39% with men only, 7.2% with both men and women and 3.2% with no one. Condom use was moderately high for anal and vaginal sex but low for oral sex. A risk index based on the riskiness of specific activities showed that bisexuals were the most likely to engage in high risk behaviour whereas homosexuals were the least likely. One factor in the greater riskiness of bisexuals' behaviour appeared to be a higher frequency of unprotected sex with women. These findings provide a preliminary portrait of sexual risk-taking among men in Singapore and suggest the need for continued emphasis on consistent condom use for penetrative sex as well as appropriate precautions for oral sex. The results also suggest the need to develop targeted interventions for bisexuals, particularly with respect to unprotected sex with women.

  11. Privacy preserving data publishing of categorical data through k-anonymity and feature selection.

    Science.gov (United States)

    Aristodimou, Aristos; Antoniades, Athos; Pattichis, Constantinos S

    2016-03-01

    In healthcare, there is a vast amount of patients' data, which can lead to important discoveries if combined. Due to legal and ethical issues, such data cannot be shared and hence such information is underused. A new area of research has emerged, called privacy preserving data publishing (PPDP), which aims in sharing data in a way that privacy is preserved while the information lost is kept at a minimum. In this Letter, a new anonymisation algorithm for PPDP is proposed, which is based on k-anonymity through pattern-based multidimensional suppression (kPB-MS). The algorithm uses feature selection for reducing the data dimensionality and then combines attribute and record suppression for obtaining k-anonymity. Five datasets from different areas of life sciences [RETINOPATHY, Single Proton Emission Computed Tomography imaging, gene sequencing and drug discovery (two datasets)], were anonymised with kPB-MS. The produced anonymised datasets were evaluated using four different classifiers and in 74% of the test cases, they produced similar or better accuracies than using the full datasets.

  12. A robust uniqueness-and-anonymity-preserving remote user authentication scheme for connected health care.

    Science.gov (United States)

    Wen, Fengtong

    2013-12-01

    User authentication plays an important role to protect resources or services from being accessed by unauthorized users. In a recent paper, Das et al. proposed a secure and efficient uniqueness-and-anonymity-preserving remote user authentication scheme for connected health care. This scheme uses three factors, e.g. biometrics, password, and smart card, to protect the security. It protects user privacy and is believed to have many abilities to resist a range of network attacks, even if the secret information stored in the smart card is compromised. In this paper, we analyze the security of Das et al.'s scheme, and show that the scheme is in fact insecure against the replay attack, user impersonation attacks and off-line guessing attacks. Then, we also propose a robust uniqueness-and-anonymity-preserving remote user authentication scheme for connected health care. Compared with the existing schemes, our protocol uses a different user authentication mechanism to resist replay attack. We show that our proposed scheme can provide stronger security than previous protocols. Furthermore, we demonstrate the validity of the proposed scheme through the BAN (Burrows, Abadi, and Needham) logic.

  13. CRYPTOGRAPHIC SECURE CLOUD STORAGE MODEL WITH ANONYMOUS AUTHENTICATION AND AUTOMATIC FILE RECOVERY

    Directory of Open Access Journals (Sweden)

    Sowmiya Murthy

    2014-10-01

    Full Text Available We propose a secure cloud storage model that addresses security and storage issues for cloud computing environments. Security is achieved by anonymous authentication which ensures that cloud users remain anonymous while getting duly authenticated. For achieving this goal, we propose a digital signature based authentication scheme with a decentralized architecture for distributed key management with multiple Key Distribution Centers. Homomorphic encryption scheme using Paillier public key cryptosystem is used for encrypting the data that is stored in the cloud. We incorporate a query driven approach for validating the access policies defined by an individual user for his/her data i.e. the access is granted to a requester only if his credentials matches with the hidden access policy. Further, since data is vulnerable to losses or damages due to the vagaries of the network, we propose an automatic retrieval mechanism where lost data is recovered by data replication and file replacement with string matching algorithm. We describe a prototype implementation of our proposed model.

  14. Moves on the Street: Classifying Crime Hotspots Using Aggregated Anonymized Data on People Dynamics.

    Science.gov (United States)

    Bogomolov, Andrey; Lepri, Bruno; Staiano, Jacopo; Letouzé, Emmanuel; Oliver, Nuria; Pianesi, Fabio; Pentland, Alex

    2015-09-01

    The wealth of information provided by real-time streams of data has paved the way for life-changing technological advancements, improving the quality of life of people in many ways, from facilitating knowledge exchange to self-understanding and self-monitoring. Moreover, the analysis of anonymized and aggregated large-scale human behavioral data offers new possibilities to understand global patterns of human behavior and helps decision makers tackle problems of societal importance. In this article, we highlight the potential societal benefits derived from big data applications with a focus on citizen safety and crime prevention. First, we introduce the emergent new research area of big data for social good. Next, we detail a case study tackling the problem of crime hotspot classification, that is, the classification of which areas in a city are more likely to witness crimes based on past data. In the proposed approach we use demographic information along with human mobility characteristics as derived from anonymized and aggregated mobile network data. The hypothesis that aggregated human behavioral data captured from the mobile network infrastructure, in combination with basic demographic information, can be used to predict crime is supported by our findings. Our models, built on and evaluated against real crime data from London, obtain accuracy of almost 70% when classifying whether a specific area in the city will be a crime hotspot or not in the following month.

  15. The long path to pregnancy: early experience with dual anonymous gamete donation in a European in vitro fertilisation referral centre.

    Science.gov (United States)

    Sills, Eric Scott; Mykhaylyshyn, Lyubov O; Dorofeyeva, Ulyana S; Walsh, David J; Salma, Umme; Omar, Ahmed B; Coull, Graham D; David, Ileana A; Brickell, Kathy M; Tsar, Olga M; Walsh, Anthony Ph

    2010-08-11

    This investigation describes features of patients undergoing in vitro fertilisation (IVF) and embryo transfer (ET) where both gametes were obtained from anonymous donors. Gamete unsuitability or loss was confirmed in both members of seven otherwise healthy couples presenting for reproductive endocrinology consultation over a 12-month interval in Ireland. IVF was undertaken with fresh oocytes provided by anonymous donors in Ukraine; frozen sperm (anonymous donor) was obtained from a licensed tissue establishment. For recipients, saline-enhanced sonography was used to assess intrauterine contour with endometrial preparation via transdermal estrogen. Among commissioning couples, mean+/-SD female and male age was 41.9 +/- 3.7 and 44.6 +/- 3.5 yrs, respectively. During this period, female age for non dual anonymous gamete donation IVF patients was 37.9 +/- 3 yrs (p /=3 yrs for couples enrolling in dual gamete donation, and each had >/=2 prior failed fertility treatments using native oocytes. All seven recipient couples proceeded to embryo transfer, although one patient had two transfers. Clinical pregnancy was achieved for 5/7 (71.4%) patients. Non-transferred cryopreserved embryos were available for all seven couples. Mean age of females undergoing dual anonymous donor gamete donation with IVF is significantly higher than the background IVF patient population. Even when neither partner is able to contribute any gametes for IVF, the clinical pregnancy rate per transfer can be satisfactory if both anonymous egg and sperm donation are used concurrently. Our report emphasises the role of pre-treatment counselling in dual anonymous gamete donation, and presents a coordinated screening and treatment approach in IVF where this option may be contemplated.

  16. The long path to pregnancy: early experience with dual anonymous gamete donation in a European in vitro fertilisation referral centre

    LENUS (Irish Health Repository)

    Sills, Eric Scott

    2010-08-11

    Abstract Background This investigation describes features of patients undergoing in vitro fertilisation (IVF) and embryo transfer (ET) where both gametes were obtained from anonymous donors. Methods Gamete unsuitability or loss was confirmed in both members of seven otherwise healthy couples presenting for reproductive endocrinology consultation over a 12-month interval in Ireland. IVF was undertaken with fresh oocytes provided by anonymous donors in Ukraine; frozen sperm (anonymous donor) was obtained from a licensed tissue establishment. For recipients, saline-enhanced sonography was used to assess intrauterine contour with endometrial preparation via transdermal estrogen. Results Among commissioning couples, mean±SD female and male age was 41.9 ± 3.7 and 44.6 ± 3.5 yrs, respectively. During this period, female age for non dual anonymous gamete donation IVF patients was 37.9 ± 3 yrs (p < 0.001). Infertility duration was ≥3 yrs for couples enrolling in dual gamete donation, and each had ≥2 prior failed fertility treatments using native oocytes. All seven recipient couples proceeded to embryo transfer, although one patient had two transfers. Clinical pregnancy was achieved for 5\\/7 (71.4%) patients. Non-transferred cryopreserved embryos were available for all seven couples. Conclusions Mean age of females undergoing dual anonymous donor gamete donation with IVF is significantly higher than the background IVF patient population. Even when neither partner is able to contribute any gametes for IVF, the clinical pregnancy rate per transfer can be satisfactory if both anonymous egg and sperm donation are used concurrently. Our report emphasises the role of pre-treatment counselling in dual anonymous gamete donation, and presents a coordinated screening and treatment approach in IVF where this option may be contemplated.

  17. Molecular markers unravel intraspecific and interspecific genetic ...

    Indian Academy of Sciences (India)

    2011). However, to develop efficient interspecific crosses it is essential to determine their phy- logenetic relationships. Although some workers have tried nuclear ribosomal DNA internal transcribed spacer (ITS) regions for this purpose (Ronsted et al. 2002; Dhar et al. 2006), it would be worthwhile to use molecular markers,.

  18. METAL DELM - metal avrelianis contribution to the study of mining coins and anonymous quadrantes

    Directory of Open Access Journals (Sweden)

    Vojvoda Mirjana D.

    2016-01-01

    Full Text Available In the course of rescue archaeological investigations at the Viminacium necropolis of Vi{e Grobalja in 1984, one anonymous quadrans of the VIII Apollo group was discovered (cat. 1. It was discovered in trench 63 in the immediate vicinity of a grave with an inhumation (G 343 that, besides two pottery vessels, also yielded as grave offerings one as of Faustina the Elder, minted after her death, in AD 141. Other finds presented here are four specimens of Roman mining coins from the private collection of Petar Fajfri} from [abac (cat. 2-5. All specimens come from the well known site of Duge Njive in the area of the village of Banatsko Polje (Bogati} borough where, by all appearances, are the remains of a vicus or smaller settlement. Five specimens of mining coins from that site have already been published. Both mining coins and anonymous quadrantes represent, in general, rare types of numismatic finds. Nine anonymous quadrantes are known so far from the territory of Serbia (Table 1 and the provenance is known for three specimens from the region of Guberevac-Babe (Kosmaj, housed in the National Museum in Belgrade. All three belong to the Minerva group with an owl facing to the right represented on the reverse. For two more anonymous quadrantes the place of discovery is known: one specimen comes from Singidunum and belongs to the Mercury group and the other that was found at Viminacium and is the subject of this paper is of the Apollo group. There are four more specimens from unknown sites for which it is assumed that they come from the Upper Moesia territory. Two of them are from the Vajfert collection and two from the Kovačević collection in the National Museum in Belgrade, There has, however, been a somewhat greater number (38 of Roman mining coins discovered in Serbia (Table 1. We know the finding locations of 25 of them: from the Kosmaj area (Babe, Guberevac and Stojnik, the Ibar valley (from the vicinity of Trepča and So~anica, Ritopek

  19. Ceramic subsurface marker prototypes

    Energy Technology Data Exchange (ETDEWEB)

    Lukens, C.E. [Rockwell International Corp., Richland, WA (United States). Rockwell Hanford Operations

    1985-05-02

    The client submitted 5 sets of porcelain and stoneware subsurface (radioactive site) marker prototypes (31 markers each set). The following were determined: compressive strength, thermal shock resistance, thermal crazing resistance, alkali resistance, color retention, and chemical resistance.

  20. Anonymous sex and HIV risk practices among men using the Internet specifically to find male partners for unprotected sex.

    Science.gov (United States)

    Klein, H

    2012-06-01

    To examine the popularity of anonymous sex practices among men using the Internet to find male partners for unprotected sex, and how anonymous sex relates to involvement in other HIV-related risk behaviours, and to investigate the factors associated with engaging in anonymous sex. Structured telephone interviews were conducted with men who used the Internet specifically to find male partners for unprotected sex. Random sampling from 16 websites was used to obtain a national sample. The data reported in this paper were based on quantitative interviews collected with a cross-sectional study design. Between January 2008 and May 2009, confidential telephone interviews lasting approximately 1-2 h were completed with 332 men. Participants were paid $35 for their participation. Most of the men (67.4%) liked anonymous sex, and slightly more than half (51.2%) had engaged in the behaviour during the month prior to interview. Involvement in anonymous sex was associated with greater involvement in a variety of human immunodeficiency virus (HIV)-related risk practices, such as illegal drug use, number of sex partners, and amount of unprotected sex. Four factors were associated with having vs not having anonymous sex: (1) being HIV positive; (2) answering all of the HIV-related knowledge questions correctly; (3) deriving greater enjoyment from having sex in public places, such as parks, public toilets, or adult book shops; and (4) greater impulsivity. Seven factors were associated with greater vs lesser involvement in anonymous sex among those practising the behaviour: (1) being involved in a relationship with a long-term partner; (2) liking to have sex in public places; (3) using bareback-oriented websites to identify sex partners; (4) greater impulsivity; (5) low level of condom use self-efficacy; (6) greater knowledge about HIV/acquired immunodeficiency syndrome; and either (7a) severe childhood maltreatment or (7b) Caucasian race. Men in this population often sought

  1. Anonymity versus privacy in the dictator game: revealing donor decisions to recipients does not substantially impact donor behavior.

    Directory of Open Access Journals (Sweden)

    Jeffrey Winking

    Full Text Available Anonymity is often offered in economic experiments in order to eliminate observer effects and induce behavior that would be exhibited under private circumstances. However, anonymity differs from privacy in that interactants are only unaware of each others' identities, while having full knowledge of each others' actions. Such situations are rare outside the laboratory and anonymity might not meet the requirements of some participants to psychologically engage as if their actions were private. In order to explore the impact of a lack of privacy on prosocial behaviors, I expand on a study reported in Dana et al. (2006 in which recipients were left unaware of the Dictator Game and given donations as "bonuses" to their show-up fees for other tasks. In the current study, I explore whether differences between a private Dictator Game (sensu Dana et al. (2006 and a standard anonymous one are due to a desire by dictators to avoid shame or to pursue prestige. Participants of a Dictator Game were randomly assigned to one of four categories-one in which the recipient knew of (1 any donation by an anonymous donor (including zero donations, (2 nothing at all, (3 only zero donations, and (4 and only non-zero donations. The results suggest that a lack of privacy increases the shame that selfish-acting participants experience, but that removing such a cost has only minimal effects on actual behavior.

  2. A robust anonymous biometric-based authenticated key agreement scheme for multi-server environments.

    Science.gov (United States)

    Guo, Hua; Wang, Pei; Zhang, Xiyong; Huang, Yuanfei; Ma, Fangchao

    2017-01-01

    In order to improve the security in remote authentication systems, numerous biometric-based authentication schemes using smart cards have been proposed. Recently, Moon et al. presented an authentication scheme to remedy the flaws of Lu et al.'s scheme, and claimed that their improved protocol supports the required security properties. Unfortunately, we found that Moon et al.'s scheme still has weaknesses. In this paper, we show that Moon et al.'s scheme is vulnerable to insider attack, server spoofing attack, user impersonation attack and guessing attack. Furthermore, we propose a robust anonymous multi-server authentication scheme using public key encryption to remove the aforementioned problems. From the subsequent formal and informal security analysis, we demonstrate that our proposed scheme provides strong mutual authentication and satisfies the desirable security requirements. The functional and performance analysis shows that the improved scheme has the best secure functionality and is computational efficient.

  3. Improving an Anonymous and Provably Secure Authentication Protocol for a Mobile User

    Directory of Open Access Journals (Sweden)

    Jongho Moon

    2017-01-01

    Full Text Available Recently many authentication protocols using an extended chaotic map were suggested for a mobile user. Many researchers demonstrated that authentication protocol needs to provide key agreement, mutual authentication, and user anonymity between mobile user and server and resilience to many possible attacks. In this paper, we cautiously analyzed chaotic-map-based authentication scheme and proved that it is still insecure to off-line identity guessing, user and server impersonation, and on-line identity guessing attacks. To address these vulnerabilities, we proposed an improved protocol based on an extended chaotic map and a fuzzy extractor. We proved the security of the proposed protocol using a random oracle and AVISPA (Automated Validation of Internet Security Protocols and Applications tool. Furthermore, we present an informal security analysis to make sure that the improved protocol is invulnerable to possible attacks. The proposed protocol is also computationally efficient when compared to other previous protocols.

  4. Female and male life stories published in the Finnish Alcoholics Anonymous journal.

    Science.gov (United States)

    Aaltonen, I; Mäkelä, K

    1994-03-01

    To study differences in how women and men describe their drinking problems, key expressions were recorded in 50 female and 50 male stories published in the Finnish A.A. (Alcoholics Anonymous) journal. Men show more interest in the past and try to understand their lives in causal terms. Women focus on the present and on experiences in A.A. Men more frequently mention narcotics and alcohol substitutes; medical drugs are more common in female stories. Men's stories more frequently contain social deviance. Women pay more attention to social relationships. The phrase Higher Power is used with equal frequency, but women more commonly use the word God. Women express more positive emotions. Registers of negative emotions differ. The drinking man is threatened by feelings of inferiority; the drinking woman by shame and guilt.

  5. A Clustering K-Anonymity Privacy-Preserving Method for Wearable IoT Devices

    Directory of Open Access Journals (Sweden)

    Fang Liu

    2018-01-01

    Full Text Available Wearable technology is one of the greatest applications of the Internet of Things. The popularity of wearable devices has led to a massive scale of personal (user-specific data. Generally, data holders (manufacturers of wearable devices are willing to share these data with others to get benefits. However, significant privacy concerns would arise when sharing the data with the third party in an improper manner. In this paper, we first propose a specific threat model about the data sharing process of wearable devices’ data. Then we propose a K-anonymity method based on clustering to preserve privacy of wearable IoT devices’ data and guarantee the usability of the collected data. Experiment results demonstrate the effectiveness of the proposed method.

  6. Safe2Tell® : an anonymous, 24/7 reporting system for preventing school violence.

    Science.gov (United States)

    Payne, Susan R T; Elliott, Delbert S

    2011-01-01

    There is widespread agreement that many school shootings could be prevented if authorities were informed that a student was planning or preparing to carry out an attack. A universal problem is that young people are highly reluctant to report on their peers. This code of silence represents a major barrier to prevention efforts. In response to the Columbine shooting, the state of Colorado established the Safe2Tell® anonymous, 24/7 reporting system for receiving and forwarding threats of violence, bullying, and other concerns. This article describes how the program has grown to the point that it now receives more than 100 calls per month. A series of case examples illustrates its success in responding to threatening situations, including twenty-eight potential school attacks. Copyright © 2011 Wiley Periodicals, Inc., A Wiley Company.

  7. Improvement of a uniqueness-and-anonymity-preserving user authentication scheme for connected health care.

    Science.gov (United States)

    Xie, Qi; Liu, Wenhao; Wang, Shengbao; Han, Lidong; Hu, Bin; Wu, Ting

    2014-09-01

    Patient's privacy-preserving, security and mutual authentication between patient and the medical server are the important mechanism in connected health care applications, such as telecare medical information systems and personally controlled health records systems. In 2013, Wen showed that Das et al.'s scheme is vulnerable to the replay attack, user impersonation attacks and off-line guessing attacks, and then proposed an improved scheme using biometrics, password and smart card to overcome these weaknesses. However, we show that Wen's scheme is still vulnerable to off-line password guessing attacks, does not provide user's anonymity and perfect forward secrecy. Further, we propose an improved scheme to fix these weaknesses, and use the applied pi calculus based formal verification tool ProVerif to prove the security and authentication.

  8. Quality of life changes in an alcoholics anonymous self-help group

    Directory of Open Access Journals (Sweden)

    INDRĖ DIRGĖLIENĖ

    2017-09-01

    Full Text Available The issue of alcohol addiction is one of the most pressing in contemporary society as it causes an effect in the context of poverty, violence and suicidal behaviour. After the restoration of Lithuania‘s Independence a new helping profession such as social worker appeared: they were expected to provide professional help to people in order to help them find inner motivation for positive socialization or re-socialization. The issue of alcohol addiction/dependence was first viewed systemically, with the understanding of the need for systemic help: social, psychological, spiritual and medical. Long-term rehabilitation centres have been created and self-help groups formed: those of Alcoholics Anonymous (AA, Al-anon (self – help groups for friends and families who have relatives suffering from alcohol and ACA (Adult Children of Alcoholics self-help group. The article analyzes the quality of life changes in an Alcoholics Anonymous self-help group. Qualitative survey data are presented in this article. Six life stories of people attending Alcoholics Anonymous (AA self-help groups are provided. The age of the participants ranges from 31 to 58. The main criterion to participate in the research is: people who have or have had problems because of alcohol usage and who are Alcoholics Anonymous self-help group (AA participants that have reached Step 12. This means they are ready to spread the message about recovering from this abuse to people who suffer from it. Deep analysis interview has been used to collect the data. Interview notional blocks are: 1 childhood experiences; 2 addiction to alcohol period and crisis; 3 changes of life quality when attending AA groups. The study data have been provided using content analysis through the deduction method. The theoretical basis is a systematic approach to a person in the course of his life‘ spiritual concepts and stages of recovery (May, 2004; Linn, Linn, 2003; Kubler-Ross, 2008 and the theory of integrated

  9. A robust anonymous biometric-based authenticated key agreement scheme for multi-server environments

    Science.gov (United States)

    Huang, Yuanfei; Ma, Fangchao

    2017-01-01

    In order to improve the security in remote authentication systems, numerous biometric-based authentication schemes using smart cards have been proposed. Recently, Moon et al. presented an authentication scheme to remedy the flaws of Lu et al.’s scheme, and claimed that their improved protocol supports the required security properties. Unfortunately, we found that Moon et al.’s scheme still has weaknesses. In this paper, we show that Moon et al.’s scheme is vulnerable to insider attack, server spoofing attack, user impersonation attack and guessing attack. Furthermore, we propose a robust anonymous multi-server authentication scheme using public key encryption to remove the aforementioned problems. From the subsequent formal and informal security analysis, we demonstrate that our proposed scheme provides strong mutual authentication and satisfies the desirable security requirements. The functional and performance analysis shows that the improved scheme has the best secure functionality and is computational efficient. PMID:29121050

  10. A robust anonymous biometric-based authenticated key agreement scheme for multi-server environments.

    Directory of Open Access Journals (Sweden)

    Hua Guo

    Full Text Available In order to improve the security in remote authentication systems, numerous biometric-based authentication schemes using smart cards have been proposed. Recently, Moon et al. presented an authentication scheme to remedy the flaws of Lu et al.'s scheme, and claimed that their improved protocol supports the required security properties. Unfortunately, we found that Moon et al.'s scheme still has weaknesses. In this paper, we show that Moon et al.'s scheme is vulnerable to insider attack, server spoofing attack, user impersonation attack and guessing attack. Furthermore, we propose a robust anonymous multi-server authentication scheme using public key encryption to remove the aforementioned problems. From the subsequent formal and informal security analysis, we demonstrate that our proposed scheme provides strong mutual authentication and satisfies the desirable security requirements. The functional and performance analysis shows that the improved scheme has the best secure functionality and is computational efficient.

  11. What affects your MS? Responses to an anonymous, Internet-based epidemiological survey.

    Science.gov (United States)

    Simmons, Rex D; Ponsonby, Anne-Louise; van der Mei, Ingrid A F; Sheridan, Peter

    2004-04-01

    Evolving information technology has raised the possibility of new methods of data collection in multiple sclerosis (MS) research. An anonymous, self-report, Internet-based survey was developed, which asked people with MS their opinion on how various extrinsic factors affected their condition. From September 2001 to July 2002, a total of 2529 people completed the questionnaire. The demographic and clinical profiles of the anonymous respondents indicated that most were likely to have MS. Common factors reported as beneficial were cannabis, cold baths, meditation and dietary factors. Common adverse factors reported were high stress, exposure to high temperatures and viral infections. There was an increasing report of high temperatures as being adverse with increasing respondent age (test for trend, P < 0.001). The adverse report of high temperatures correlated significantly with the report of strong sunlight apparently making MS worse (r = 0.35, P < 0.0001). In Australia, high temperatures were more likely to be reported as adverse in warmer, lower latitude regions. The association between strong sunlight as adverse and age or region did not persist after adjustment for high temperatures. Thus, this apparent adverse factor appeared to relate to solar heat, not solar light. People with MS may risk vitamin D deficiency because of sun avoidance due to heat-related fatigue or intolerance. This is of clinical significance not only for bone health but because vitamin D may have beneficial immunomodulatory properties. The present study provides new information from people with MS on factors that may influence symptoms or clinical course. This information will now be used in the design of formal epidemiological cohort studies.

  12. Nuclear law - Nuclear safety

    International Nuclear Information System (INIS)

    Pontier, Jean-Marie; Roux, Emmanuel; Leger, Marc; Deguergue, Maryse; Vallar, Christian; Pissaloux, Jean-Luc; Bernie-Boissard, Catherine; Thireau, Veronique; Takahashi, Nobuyuki; Spencer, Mary; Zhang, Li; Park, Kyun Sung; Artus, J.C.

    2012-01-01

    This book contains the contributions presented during a one-day seminar. The authors propose a framework for a legal approach to nuclear safety, a discussion of the 2009/71/EURATOM directive which establishes a European framework for nuclear safety in nuclear installations, a comment on nuclear safety and environmental governance, a discussion of the relationship between citizenship and nuclear, some thoughts about the Nuclear Safety Authority, an overview of the situation regarding the safety in nuclear waste burying, a comment on the Nome law with respect to electricity price and nuclear safety, a comment on the legal consequences of the Fukushima accident on nuclear safety in the Japanese law, a presentation of the USA nuclear regulation, an overview of nuclear safety in China, and a discussion of nuclear safety in the medical sector

  13. Is the introduction of anonymous delivery associated with a reduction of high neonaticide rates in Austria? A retrospective study.

    Science.gov (United States)

    Klier, C M; Grylli, C; Amon, S; Fiala, C; Weizmann-Henelius, G; Pruitt, S L; Putkonen, H

    2013-03-01

    To assess rates of neonaticide after the implementation of a preventative 'anonymous delivery' law in mid-2001 in Austria. Women are allowed to access antenatal care and give birth in a hospital anonymously, without showing any ID and free of charge. Retrospective study. A complete census of police-reported neonaticides was obtained from the police statistics of Austria, Sweden and Finland. All neonaticides reported to the police, 1991-2009. Neonaticide rates before (1991-2001) and after (2002-2009) the introduction of anonymous delivery legislation per 100 000 births. The Mann-Whitney U-test for two independent samples was used to compare neonaticide rates in the period before the new law was introduced with the rates observed after the implementation of the new law for each country. On average the rate of police-reported neonaticides was 7.2 per 100 000 births (SD 3.5, median 7.1) in Austria prior to the new law being passed, and 3.1 per 100 000 births (SD 2.1, median 2.6) after the law was passed. A significant decrease in neonaticide was observed in Austria after the implementation of anonymous delivery (Mann-Whitney U-test P = 0.017). Whereas the Finnish and Swedish rates were lower than the Austrian rates before and after the implementation of the Austrian law, they remained unchanged over the study period. Our data demonstrate a significant decrease in the number of police-reported neonaticides in Austria after the implementation of anonymous delivery. Even though underlying factors associated with neonaticide are complex, the findings could indicate an effect of anonymous delivery in the prevention of this crime. © 2012 The Authors BJOG An International Journal of Obstetrics and Gynaecology © 2012 RCOG.

  14. “The Question Exists, but You Don’t Exist With It”: Strategic Anonymity in the Social Lives of Adolescents

    OpenAIRE

    Nicole B. Ellison; Lindsay Blackwell; Cliff Lampe; Penny Trieu

    2016-01-01

    Anonymous interactions may have important implications for adolescents’ social and psychological development. In this article, we use semi-structured interview data collected from US adolescents aged 13–18 years ( N  = 22) to explore how the specific affordances of an online platform that enables selective anonymity shape adolescents’ practices and perceptions. We contribute to scholarship on the effects of anonymous interaction online by surfacing positive outcomes for young adults who choos...

  15. Isolation of anonymous DNA sequences from within a submicroscopic X chromosomal deletion in a patient with choroideremia, deafness, and mental retardation

    International Nuclear Information System (INIS)

    Nussbaum, R.L.; Lesko, J.G.; Lewis, R.A.; Ledbetter, S.A.; Ledbetter, D.H.

    1987-01-01

    Choroideremia, an X-chromosome linked retinal dystrophy of unknown pathogenesis, causes progressive nightblindness and eventual central blindness in affected males by the third to fourth decade of life. Choroideremia has been mapped to Xq13-21 by tight linkage to restriction fragment length polymorphism loci. The authors have recently identified two families in which choroideremia is inherited with mental retardation and deafness. In family XL-62, an interstitial deletion Xq21 is visible by cytogenetic analysis and two linked anonymous DNA markers, DXYS1 and DXS72, are deleted. In the second family, XL-45, an interstitial deletion was suspected on phenotypic grounds but could not be confirmed by high-resolution cytogenetic analysis. They used phenol-enhanced reassociation of 48,XXXX DNA in competition with excess XL-45 DNA to generate a library of cloned DNA enriched for sequences that might be deleted in XL-45. Two of the first 83 sequences characterized from the library were found to be deleted in probands from family XL-45 as well as from family XL-62. Isolation of these sequences proves that XL-45 does contain a submicroscopic deletion and provides a starting point for identifying overlapping genomic sequences that span the XL-45 deletion. Each overlapping sequence will be studied to identify exons from the choroideremia locus

  16. Tantalum markers in radiography

    International Nuclear Information System (INIS)

    Aronson, A.S.; Jonsson, N.; Alberius, P.

    1985-01-01

    The biocompatibility of two types of radiopaque tantalum markers was evaluated histologically. Reactions to pin markers (99.9% purity) and spherical markers (95.2% purity) were investigated after 3-6 weeks in rabbits and 5-48 weeks in children with abnormal growth. Both marker types were firmly attached to bone trabeculae; this was most pronounced in rabbit bone, and no adverse macroscopic reactions were observed. Microscopically, no reactions or only slight fibrosis of bone tissue were detected, while soft tissues only demonstrated a minor inflammatory reaction. Nevertheless, the need for careful preparation and execution of marker implantations is stressed, and particularly avoidance iof the use of emery in sharpening of cannulae. The bioinertness of tantalum was reconfirmed as was its suitability for use as skeletal and soft tissue radiographic markers. (orig.)

  17. Alcoholics Anonymous and Relapse Prevention as Maintenance Strategies After Conjoint Behavioral Alcohol Treatment for Men: 18-Month Outcomes

    Science.gov (United States)

    McCrady, Barbara S.; Epstein, Elizabeth E.; Kahler, Christopher W.

    2004-01-01

    Ninety men with alcohol problems and their female partners were randomly assigned to 1 of 3 outpatient conjoint treatments: alcohol behavioral couples therapy (ABCT), ABCT with relapse prevention techniques (RP/ABCT), or ABCT with interventions encouraging Alcoholics Anonymous (AA) involvement (AA/ABCT). Couples were followed for 18 months after…

  18. Location Prediction Based on Transition Probability Matrices Constructing from Sequential Rules for Spatial-Temporal K-Anonymity Dataset.

    Directory of Open Access Journals (Sweden)

    Haitao Zhang

    Full Text Available Spatial-temporal k-anonymity has become a mainstream approach among techniques for protection of users' privacy in location-based services (LBS applications, and has been applied to several variants such as LBS snapshot queries and continuous queries. Analyzing large-scale spatial-temporal anonymity sets may benefit several LBS applications. In this paper, we propose two location prediction methods based on transition probability matrices constructing from sequential rules for spatial-temporal k-anonymity dataset. First, we define single-step sequential rules mined from sequential spatial-temporal k-anonymity datasets generated from continuous LBS queries for multiple users. We then construct transition probability matrices from mined single-step sequential rules, and normalize the transition probabilities in the transition matrices. Next, we regard a mobility model for an LBS requester as a stationary stochastic process and compute the n-step transition probability matrices by raising the normalized transition probability matrices to the power n. Furthermore, we propose two location prediction methods: rough prediction and accurate prediction. The former achieves the probabilities of arriving at target locations along simple paths those include only current locations, target locations and transition steps. By iteratively combining the probabilities for simple paths with n steps and the probabilities for detailed paths with n-1 steps, the latter method calculates transition probabilities for detailed paths with n steps from current locations to target locations. Finally, we conduct extensive experiments, and correctness and flexibility of our proposed algorithm have been verified.

  19. Location Prediction Based on Transition Probability Matrices Constructing from Sequential Rules for Spatial-Temporal K-Anonymity Dataset.

    Science.gov (United States)

    Zhang, Haitao; Chen, Zewei; Liu, Zhao; Zhu, Yunhong; Wu, Chenxue

    2016-01-01

    Spatial-temporal k-anonymity has become a mainstream approach among techniques for protection of users' privacy in location-based services (LBS) applications, and has been applied to several variants such as LBS snapshot queries and continuous queries. Analyzing large-scale spatial-temporal anonymity sets may benefit several LBS applications. In this paper, we propose two location prediction methods based on transition probability matrices constructing from sequential rules for spatial-temporal k-anonymity dataset. First, we define single-step sequential rules mined from sequential spatial-temporal k-anonymity datasets generated from continuous LBS queries for multiple users. We then construct transition probability matrices from mined single-step sequential rules, and normalize the transition probabilities in the transition matrices. Next, we regard a mobility model for an LBS requester as a stationary stochastic process and compute the n-step transition probability matrices by raising the normalized transition probability matrices to the power n. Furthermore, we propose two location prediction methods: rough prediction and accurate prediction. The former achieves the probabilities of arriving at target locations along simple paths those include only current locations, target locations and transition steps. By iteratively combining the probabilities for simple paths with n steps and the probabilities for detailed paths with n-1 steps, the latter method calculates transition probabilities for detailed paths with n steps from current locations to target locations. Finally, we conduct extensive experiments, and correctness and flexibility of our proposed algorithm have been verified.

  20. Opinions of Dutch Liver Transplant Recipients on Anonymity of Organ Donation and Direct Contact With the Donors Family

    NARCIS (Netherlands)

    Annema-de Jong, Coby; op den Dries, Sanna; van den Berg, Aad P.; Ranchor, Adelita V.; Porte, Robert J.

    Background. In the Netherlands, anonymity of organ donation, which is currently protected by legislation, has come under discussion. In the Dutch society, a tendency to allow direct contact between transplant recipients and their donor's family is noticeable. As little is known about the opinion of

  1. Increasing Anonymity in Peer Assessment by Using Classroom Response Technology within Face-to-Face Higher Education

    Science.gov (United States)

    Raes, Annelies; Vanderhoven, Ellen; Schellens, Tammy

    2015-01-01

    Peer assessment is becoming more popular in higher education, however it often goes together with undesirable social effects like peer pressure and favoritism, especially when students need to evaluate peers in a face-to-face setting. The present study was set up to investigate increased anonymity in peer assessment to counter these undesirable…

  2. Location Prediction Based on Transition Probability Matrices Constructing from Sequential Rules for Spatial-Temporal K-Anonymity Dataset

    Science.gov (United States)

    Liu, Zhao; Zhu, Yunhong; Wu, Chenxue

    2016-01-01

    Spatial-temporal k-anonymity has become a mainstream approach among techniques for protection of users’ privacy in location-based services (LBS) applications, and has been applied to several variants such as LBS snapshot queries and continuous queries. Analyzing large-scale spatial-temporal anonymity sets may benefit several LBS applications. In this paper, we propose two location prediction methods based on transition probability matrices constructing from sequential rules for spatial-temporal k-anonymity dataset. First, we define single-step sequential rules mined from sequential spatial-temporal k-anonymity datasets generated from continuous LBS queries for multiple users. We then construct transition probability matrices from mined single-step sequential rules, and normalize the transition probabilities in the transition matrices. Next, we regard a mobility model for an LBS requester as a stationary stochastic process and compute the n-step transition probability matrices by raising the normalized transition probability matrices to the power n. Furthermore, we propose two location prediction methods: rough prediction and accurate prediction. The former achieves the probabilities of arriving at target locations along simple paths those include only current locations, target locations and transition steps. By iteratively combining the probabilities for simple paths with n steps and the probabilities for detailed paths with n-1 steps, the latter method calculates transition probabilities for detailed paths with n steps from current locations to target locations. Finally, we conduct extensive experiments, and correctness and flexibility of our proposed algorithm have been verified. PMID:27508502

  3. An Anonymous Survey of Psychosomatic Medicine Fellowship Directors regarding Breaches of Contracts and a Proposal for Prevention

    Science.gov (United States)

    Levenson, James L.; Bialer, Philip

    2010-01-01

    Objective: The authors studied how often applicants accept positions at more than one program, or programs offer positions to applicants who have already signed contracts with other programs. Methods: An anonymous survey was distributed to all psychosomatic medicine fellowship program directors. Results: It is fairly common for applicants to sign…

  4. Long-Term Influence of Duration and Frequency of Participation in Alcoholics Anonymous on Individuals With Alcohol Use Disorders.

    Science.gov (United States)

    Moos, Rudolf H.; Moos, Bernice S.

    2004-01-01

    This study examined the influence of the duration and frequency of a baseline episode of participation in Alcoholics Anonymous (AA) among 473 individuals with alcohol use disorders on 1-year and 8-year outcomes and the effect of additional participation and delayed participation on outcomes. Compared with individuals who did not participate,…

  5. Conducting Anonymous, Incentivized, Online Surveys With Sexual and Gender Minority Adolescents: Lessons Learned From a National Polyvictimization Study.

    Science.gov (United States)

    Sterzing, Paul R; Gartner, Rachel E; McGeough, Briana L

    2018-03-01

    Sexual and gender minority adolescents represent an understudied and hard-to-reach population who experience higher rates of mental and behavioral health problems in comparison to their cisgender, heterosexual peers. Online surveys and the proliferation of Internet-connected devices among adolescents offer an exciting opportunity for researchers to begin addressing research gaps and past methodological limitations with these hard-to-reach populations. The purpose of this article is to provide guidance to researchers who are designing and implementing anonymous, incentivized, online surveys by examining the following critical domains-(a) recruitment and engagement: means of leveraging social media and videos to recruit and engage a more nationally representative sample; (b) safety and protection: strategies for administering informed consent and protecting participant anonymity and well-being; and (c) data integrity: mechanisms to detect dishonest and repeat responders. To facilitate discussion of these aims, concrete examples are used from SpeakOut-a 3-year, national study funded by the National Institute of Justice that utilized an anonymous, incentivized, online survey with a large sample of sexual and gender minority adolescents ( N = 1,177) to identify the prevalence, incidence, and correlates of polyvictimization. The article concludes with lessons learned from this national study and recommendations for technological innovations and future research that will strengthen the utility of anonymous, incentivized, online surveys to study sexual and gender minority adolescents and other hard-to-reach populations.

  6. Attachment Styles and Changes among Women Members of Overeaters Anonymous Who Have Recovered from Binge-Eating Disorder

    Science.gov (United States)

    Hertz, Pnina; Addad, Moshe; Ronel, Natti

    2012-01-01

    In Overeaters Anonymous (OA), the 12-step self-help program for compulsive overeaters, binge eating is regarded as a physical, spiritual, and emotional disorder. Consequently, the program proposes recovery through the adoption of a lifestyle that leads to physical, spiritual, and emotional well-being. A qualitative phenomenological study that…

  7. Development of microsatellite markers using next-generation sequencing for the fish Colossoma macropomum.

    Science.gov (United States)

    Ariede, Raquel B; Freitas, Milena V; Hata, Milene E; Matrochirico-Filho, Vito A; Utsunomia, Ricardo; Mendonça, Fernando F; Foresti, Fausto; Porto-Foresti, Fábio; Hashimoto, Diogo T

    2018-02-01

    Tambaqui (Colossoma macropomum) is a fish species from the Amazon and Orinoco Rivers, with favorable characteristics to the cultivation system and great market acceptance in South America. However, the construction of a genetic map for the genetic improvement of this species is limited by the low number of molecular markers currently described. Thus, this study aimed to validate gene-associated and anonymous (non-genic) microsatellites obtained by next generation sequencing (RNA-seq and whole genome shotgun-WGS, respectively), for future construction of a genetic map and search for quantitative trait loci (QTL) in this species. In the RNA-seq data, the observed and expected heterozygosity (H o and H e ) ranged from 0.09 to 0.73, and 0.09 to 0.85, respectively. In the WGS data, H o and H e ranged from 0.33 to 0.95, and 0.28 to 0.92, respectively. In general, the evaluation of 200 markers resulted in 45 polymorphic loci, of which 14 were gene-associated (RNA-Seq) and 31 were anonymous (WGS). Moreover, some markers were related to genes of the immune system, biological regulation/control and biogenesis. This study contributes to increase the number of molecular markers available for genetic studies in C. macropomum, which will allow the development of breeding programs assisted by molecular markers.

  8. Preference for anonymity in sperm donation for artificial insemination: an experience from low-resource settings in Nigeria

    Science.gov (United States)

    Ezugwu, Euzebus Chinonye; Eleje, George U; Iyoke, Chukwuemeka A; Mba, Sunday G; Nnaji, Henry C; Enechukwu, Chukwunonso I; Nkwo, Peter O

    2018-01-01

    Objective Anonymous sperm donation is a common practice in Nigeria with its associated legal and ethical challenges. This study aimed to investigate infertile couples’ opinions about issues of sperm donor anonymity and to determine factors that might influence their preferences. Methods A cross-sectional, multicentered, questionnaire-based study was conducted among infertile couples attending infertility clinics in three tertiary hospitals in the south-eastern region of Nigeria over a period of 6 months. Results A total of 450 infertile couples were recruited consecutively from the three study centers. However, 450 females and 352 males (total=802) participated in the study. The level of awareness of artificial insemination using donor sperm for the management of male infertility among the respondents was 69.2%, while its acceptability rate was 62.7%. The majority of the respondents indicated their preference for secrecy and anonymity in sperm donation. Approximately 84% of the respondents indicated that the mode of conception should never be disclosed to the donor-conceived child, and ~92% of them indicated that the identity of the sperm donor should never be revealed to the donor-conceived child. Fear of adverse effect of such disclosure on the child and the possible of rejection of the father in order to seek for the donor were the major reasons for their preference for anonymity. Conclusion Although it has been argued that every child has a right to know their genetic parents, the reasons proffered by the respondents for their preference for anonymity cannot be totally ignored. Establishing a regulatory body and enacting laws that will address both the ethical and legal issues associated with gamete donation in the developing world will go a long way in promoting openness and honest communication with donor-conceived children. PMID:29670338

  9. A more secure anonymous user authentication scheme for the integrated EPR information system.

    Science.gov (United States)

    Wen, Fengtong

    2014-05-01

    Secure and efficient user mutual authentication is an essential task for integrated electronic patient record (EPR) information system. Recently, several authentication schemes have been proposed to meet this requirement. In a recent paper, Lee et al. proposed an efficient and secure password-based authentication scheme used smart cards for the integrated EPR information system. This scheme is believed to have many abilities to resist a range of network attacks. Especially, they claimed that their scheme could resist lost smart card attack. However, we reanalyze the security of Lee et al.'s scheme, and show that it fails to protect off-line password guessing attack if the secret information stored in the smart card is compromised. This also renders that their scheme is insecure against user impersonation attacks. Then, we propose a new user authentication scheme for integrated EPR information systems based on the quadratic residues. The new scheme not only resists a range of network attacks but also provides user anonymity. We show that our proposed scheme can provide stronger security.

  10. Evolution of fairness in the one-shot anonymous Ultimatum Game.

    Science.gov (United States)

    Rand, David G; Tarnita, Corina E; Ohtsuki, Hisashi; Nowak, Martin A

    2013-02-12

    Classical economic models assume that people are fully rational and selfish, while experiments often point to different conclusions. A canonical example is the Ultimatum Game: one player proposes a division of a sum of money between herself and a second player, who either accepts or rejects. Based on rational self-interest, responders should accept any nonzero offer and proposers should offer the smallest possible amount. Traditional, deterministic models of evolutionary game theory agree: in the one-shot anonymous Ultimatum Game, natural selection favors low offers and demands. Experiments instead show a preference for fairness: often responders reject low offers and proposers make higher offers than needed to avoid rejection. Here we show that using stochastic evolutionary game theory, where agents make mistakes when judging the payoffs and strategies of others, natural selection favors fairness. Across a range of parameters, the average strategy matches the observed behavior: proposers offer between 30% and 50%, and responders demand between 25% and 40%. Rejecting low offers increases relative payoff in pairwise competition between two strategies and is favored when selection is sufficiently weak. Offering more than you demand increases payoff when many strategies are present simultaneously and is favored when mutation is sufficiently high. We also perform a behavioral experiment and find empirical support for these theoretical findings: uncertainty about the success of others is associated with higher demands and offers; and inconsistency in the behavior of others is associated with higher offers but not predictive of demands. In an uncertain world, fairness finishes first.

  11. Prospective parents' intentions regarding disclosure following the removal of donor anonymity.

    Science.gov (United States)

    Crawshaw, Marilyn

    2008-06-01

    This short survey of UK infertility counsellors was designed to determine whether the removal of donor anonymity resulted in noticeable changes in prospective parents' stated intentions regarding disclosure of their origins to any children conceived through donor conception. Members of the British Infertility Counselling Association working in Human Fertilisation and Embryology Authority (HFEA) -- licensed centres, before and after the legal changes, were sent a short questionnaire that included space for free comments (take-up: 62%). Three-quarters reported changes. Of these, two-thirds said prospective parents were more likely to say they would disclose, while less than a tenth said prospective parents were less likely do so. Where no changes were noted, this was primarily because the majority of prospective parents had stated their intention to be open even prior to the legal changes. Possible influences on intentions included: the culture within the centre, moves towards openness within the wider society, and parents' lack of confidence regarding how to go about disclosure. Follow-up studies are needed to improve understanding of whether influences on decision making carry through to patterns of actual disclosure; whether involvement in counselling affects outcomes; and whether access to professional assistance at the time of planned disclosure is helpful.

  12. Cardinality Estimation Algorithm in Large-Scale Anonymous Wireless Sensor Networks

    KAUST Repository

    Douik, Ahmed

    2017-08-30

    Consider a large-scale anonymous wireless sensor network with unknown cardinality. In such graphs, each node has no information about the network topology and only possesses a unique identifier. This paper introduces a novel distributed algorithm for cardinality estimation and topology discovery, i.e., estimating the number of node and structure of the graph, by querying a small number of nodes and performing statistical inference methods. While the cardinality estimation allows the design of more efficient coding schemes for the network, the topology discovery provides a reliable way for routing packets. The proposed algorithm is shown to produce a cardinality estimate proportional to the best linear unbiased estimator for dense graphs and specific running times. Simulation results attest the theoretical results and reveal that, for a reasonable running time, querying a small group of nodes is sufficient to perform an estimation of 95% of the whole network. Applications of this work include estimating the number of Internet of Things (IoT) sensor devices, online social users, active protein cells, etc.

  13. 20 Questions of Gamblers Anonymous: A Psychometric Study with Population of Spain.

    Science.gov (United States)

    Ursua, María Prieto; Uribelarrea, Luis Llavona

    1998-01-01

    The authors present a psychometric study of the questionnaire proposed by the Gamblers Anonymous organization for the self-assessment of problem gambling. The study was carried out in Spain with two samples: one of 127 problem gamblers (mean age: 41.67; sex: 78.7% men; mean duration of the problem: 5 years) and the other of 142 social gamblers (mean age: 38.46; sex: 60% men). The questionnaire was self-applied, in the presence of one of the investigators in case any doubts arose. The results indicate that it is a good screening instrument, with high reliability (Cronbach's alpha = 0.94), good covergent validity (the correlation with the SOGS questionnaire is high (r = 0.94; p < 0.001)), good factorial validity (the questionnaire's structure is unidimensional and coherent (just one factor explains more than 50% of the variance)), and its discriminative power is high (diagnostic efficacy = 98.88%). The study offers a comparative analysis of this instrument with other measures of problem gambling, emphasizing its extraordinary performance.

  14. Patterns and correlates of Gamblers Anonymous attendance in pathological gamblers seeking professional treatment.

    Science.gov (United States)

    Petry, Nancy M

    2003-08-01

    Although Gamblers Anonymous (GA) is a popular intervention for gamblers, many attendees later present for professional treatment. This study evaluated gambling and psychosocial problems in individuals seeking professional treatment for gambling and compared those with and without a history of GA attendance. At intake to treatment, 342 pathological gamblers completed the Addiction Severity Index (ASI) and South Oaks Gambling Screen (SOGS). Fifty-four percent attended GA previously. Compared to non-GA attendees, GA attendees were older, had higher incomes, and were less likely to be single. They had higher SOGS scores, more years of gambling problems, and larger debts. GA attendees also had more serious family conflicts and less serious drug problems. Individuals with a history of GA attendance were more likely to be abstinent from gambling 2 months after treatment initiation. Logistic regression revealed that the number of professional sessions and GA meetings attended during treatment was independently associated with short-term abstinence. These data suggest that individuals entering professional treatment for gambling with a history of GA attendance differ from those who do not, and these differences may impact treatment recommendations and outcomes.

  15. Psychosocial factors related to gambling abstinence and relapse in members of gamblers anonymous.

    Science.gov (United States)

    Oei, Tian P S; Gordon, Leon M

    2008-03-01

    Problem gamblers account for almost one-third of the industry's total revenue with the adverse effects of problem gambling including significant financial loss, legal and occupational difficulties, family problems, psychological distress and suicide. As such, it is important to understand the influential factors in gambling abstinence and relapse, which will assist in the development of relapse prevention methods in therapeutic treatment regimes. This paper reported the role of a set of seven predictors in distinguishing between abstinent and relapsed gamblers among 75 Gambling Anonymous (GA) members (55 males; 20 females; Mean age 45 years) in Southeast Queensland. The measures taken were meeting Attendance and Participation, Social Support, God Belief, Belief in a Higher Power, Working the 12-steps of Recovery, Gambling Urges and Erroneous Cognitions. Discriminant analysis revealed that the variables separating the two groups were significant, suggesting that GA members achieving abstinence could be distinguished from those who relapsed, with Attendance and Participation, and Social Support contributing the greatest influence on member's ability to abstain from gambling. The findings suggested that GA member's involvement in meetings, and support from family and friends had significant impact on their gambling abstinence. In contrast, increased gambling urges and erroneous cognitions increased the chance of relapse.

  16. Alcoholics Anonymous and twelve-step recovery: a model based on social and cognitive neuroscience.

    Science.gov (United States)

    Galanter, Marc

    2014-01-01

    In the course of achieving abstinence from alcohol, longstanding members of Alcoholics Anonymous (AA) typically experience a change in their addiction-related attitudes and behaviors. These changes are reflective of physiologically grounded mechanisms which can be investigated within the disciplines of social and cognitive neuroscience. This article is designed to examine recent findings associated with these disciplines that may shed light on the mechanisms underlying this change. Literature review and hypothesis development. Pertinent aspects of the neural impact of drugs of abuse are summarized. After this, research regarding specific brain sites, elucidated primarily by imaging techniques, is reviewed relative to the following: Mirroring and mentalizing are described in relation to experimentally modeled studies on empathy and mutuality, which may parallel the experiences of social interaction and influence on AA members. Integration and retrieval of memories acquired in a setting like AA are described, and are related to studies on storytelling, models of self-schema development, and value formation. A model for ascription to a Higher Power is presented. The phenomena associated with AA reflect greater complexity than the empirical studies on which this article is based, and certainly require further elucidation. Despite this substantial limitation in currently available findings, there is heuristic value in considering the relationship between the brain-based and clinical phenomena described here. There are opportunities for the study of neuroscientific correlates of Twelve-Step-based recovery, and these can potentially enhance our understanding of related clinical phenomena. © American Academy of Addiction Psychiatry.

  17. LPPS: A Distributed Cache Pushing Based K-Anonymity Location Privacy Preserving Scheme

    Directory of Open Access Journals (Sweden)

    Ming Chen

    2016-01-01

    Full Text Available Recent years have witnessed the rapid growth of location-based services (LBSs for mobile social network applications. To enable location-based services, mobile users are required to report their location information to the LBS servers and receive answers of location-based queries. Location privacy leak happens when such servers are compromised, which has been a primary concern for information security. To address this issue, we propose the Location Privacy Preservation Scheme (LPPS based on distributed cache pushing. Unlike existing solutions, LPPS deploys distributed cache proxies to cover users mostly visited locations and proactively push cache content to mobile users, which can reduce the risk of leaking users’ location information. The proposed LPPS includes three major process. First, we propose an algorithm to find the optimal deployment of proxies to cover popular locations. Second, we present cache strategies for location-based queries based on the Markov chain model and propose update and replacement strategies for cache content maintenance. Third, we introduce a privacy protection scheme which is proved to achieve k-anonymity guarantee for location-based services. Extensive experiments illustrate that the proposed LPPS achieves decent service coverage ratio and cache hit ratio with lower communication overhead compared to existing solutions.

  18. Identification of genes in anonymous DNA sequences. Annual performance report, February 1, 1991--January 31, 1992

    Energy Technology Data Exchange (ETDEWEB)

    Fields, C.A.

    1996-06-01

    The objective of this project is the development of practical software to automate the identification of genes in anonymous DNA sequences from the human, and other higher eukaryotic genomes. A software system for automated sequence analysis, gm (gene modeler) has been designed, implemented, tested, and distributed to several dozen laboratories worldwide. A significantly faster, more robust, and more flexible version of this software, gm 2.0 has now been completed, and is being tested by operational use to analyze human cosmid sequence data. A range of efforts to further understand the features of eukaryoyic gene sequences are also underway. This progress report also contains papers coming out of the project including the following: gm: a Tool for Exploratory Analysis of DNA Sequence Data; The Human THE-LTR(O) and MstII Interspersed Repeats are subfamilies of a single widely distruted highly variable repeat family; Information contents and dinucleotide compostions of plant intron sequences vary with evolutionary origin; Splicing signals in Drosophila: intron size, information content, and consensus sequences; Integration of automated sequence analysis into mapping and sequencing projects; Software for the C. elegans genome project.

  19. An initial fMRI study on neural correlates of prayer in members of Alcoholics Anonymous.

    Science.gov (United States)

    Galanter, Marc; Josipovic, Zoran; Dermatis, Helen; Weber, Jochen; Millard, Mary Alice

    2017-01-01

    Many individuals with alcohol-use disorders who had experienced alcohol craving before joining Alcoholics Anonymous (AA) report little or no craving after becoming long-term members. Their use of AA prayers may contribute to this. Neural mechanisms underlying this process have not been delineated. To define experiential and neural correlates of diminished alcohol craving following AA prayers among members with long-term abstinence. Twenty AA members with long-term abstinence participated. Self-report measures and functional magnetic resonance imaging of differential neural response to alcohol-craving-inducing images were obtained in three conditions: after reading of AA prayers, after reading irrelevant news, and with passive viewing. Random-effects robust regressions were computed for the main effect (prayer > passive + news) and for estimating the correlations between the main effect and the self-report measures. Compared to the other two conditions, the prayer condition was characterized by: less self-reported craving; increased activation in left-anterior middle frontal gyrus, left superior parietal lobule, bilateral precuneus, and bilateral posterior middle temporal gyrus. Craving following prayer was inversely correlated with activation in brain areas associated with self-referential processing and the default mode network, and with characteristics reflecting AA program involvement. AA members' prayer was associated with a relative reduction in self-reported craving and with concomitant engagement of neural mechanisms that reflect control of attention and emotion. These findings suggest neural processes underlying the apparent effectiveness of AA prayer.

  20. Parents' perception of self-advocacy of children with myositis: an anonymous online survey

    Directory of Open Access Journals (Sweden)

    Huber Adam M

    2011-06-01

    Full Text Available Abstract Background Children with complex medical issues experience barriers to the transition of care from pediatric to adult providers. We sought to identify these barriers by elucidating the experiences of patients with idiopathic inflammatory muscle disorders. Methods We collected anonymous survey data using an online website. Patients and their families were solicited from the US and Canada through established clinics for children with idiopathic inflammatory muscle diseases as well as with the aid of a nonprofit organization for the benefit of such individuals. The parents of 45 older children/young adults suffering from idiopathic inflammatory muscle diseases were surveyed. As a basis of comparison, we similarly collected data from the parents of 207 younger children with inflammatory muscle diseases. The survey assessed transition of care issues confronting families of children and young adults with chronic juvenile myositis. Results Regardless of age of the patient, respondents were unlikely to have a designated health care provider assigned to aid in transition of care and were unlikely to be aware of a posted policy concerning transition of care at their pediatrician's office. Additionally, regardless of age, patients and their families were unlikely to have a written plan for moving to adult care. Conclusions We identified deficiencies in the health care experiences of families as pertain to knowledge, self-advocacy, policy, and vocational readiness. Moreover, as children with complex medical issues grow up, parents attribute less self-advocacy to their children's level of independence.

  1. A uniqueness-and-anonymity-preserving remote user authentication scheme for connected health care.

    Science.gov (United States)

    Chang, Ya-Fen; Yu, Shih-Hui; Shiao, Ding-Rui

    2013-04-01

    Connected health care provides new opportunities for improving financial and clinical performance. Many connected health care applications such as telecare medicine information system, personally controlled health records system, and patient monitoring have been proposed. Correct and quality care is the goal of connected heath care, and user authentication can ensure the legality of patients. After reviewing authentication schemes for connected health care applications, we find that many of them cannot protect patient privacy such that others can trace users/patients by the transmitted data. And the verification tokens used by these authentication schemes to authenticate users or servers are only password, smart card and RFID tag. Actually, these verification tokens are not unique and easy to copy. On the other hand, biometric characteristics, such as iris, face, voiceprint, fingerprint and so on, are unique, easy to be verified, and hard to be copied. In this paper, a biometrics-based user authentication scheme will be proposed to ensure uniqueness and anonymity at the same time. With the proposed scheme, only the legal user/patient himself/herself can access the remote server, and no one can trace him/her according to transmitted data.

  2. Personality Patterns in Narcotics Anonymous Members versus Individuals with Addiction Receiving Methadone Maintenance Therapy.

    Directory of Open Access Journals (Sweden)

    Shahin Akhondzadeh

    2014-09-01

    Full Text Available Therapeutic interventions can be classified into two distinct approaches: abstinent and maintenance method. Currently, there are no clear criteria for referring addicted patients to one of these modalities. We aimed to compare the personality characteristics of individuals with addiction who attended narcotics anonymous sessions with those who received methadone maintenance therapy.This was a cross- sectional study. The participants were NA members and patients who were undergoing methadone maintenance treatment in outpatient clinics. Using the randomized cluster sampling method, 200 individuals with opioid dependence were selected (each group 100 persons. Data were collected through a demographic questionnaire and the five-factor personality inventory (NEO-FFI. Comparison of the mean scores of NEO-PPI in the two groups was performed by independent t test, and qualitative variables were compared using the Chi-square test.We found a significant difference between the MMT and NA groups with respect to neuroticism, extroversion, and agreeableness. No significant difference was found in the subscales of conscientious and openness.People who regularly attended the NA sessions had lower neuroticism and higher agreeableness than patients who were under the maintenance modality. Whether this is the cause or effect of attending NA sessions requires future large-scale cohort studies.

  3. Distributed Performance Measurement and Usability Assessment of the Tor Anonymization Network

    Directory of Open Access Journals (Sweden)

    Steffen Kunz

    2012-05-01

    Full Text Available While the Internet increasingly permeates everyday life of individuals around the world, it becomes crucial to prevent unauthorized collection and abuse of personalized information. Internet anonymization software such as Tor is an important instrument to protect online privacy. However, due to the performance overhead caused by Tor, many Internet users refrain from using it. This causes a negative impact on the overall privacy provided by Tor, since it depends on the size of the user community and availability of shared resources. Detailed measurements about the performance of Tor are crucial for solving this issue. This paper presents comparative experiments on Tor latency and throughput for surfing to 500 popular websites from several locations around the world during the period of 28 days. Furthermore, we compare these measurements to critical latency thresholds gathered from web usability research, including our own user studies. Our results indicate that without massive future optimizations of Tor performance, it is unlikely that a larger part of Internet users would adopt it for everyday usage. This leads to fewer resources available to the Tor community than theoretically possible, and increases the exposure of privacy-concerned individuals. Furthermore, this could lead to an adoption barrier of similar privacy-enhancing technologies for a Future Internet.

  4. Intuitive presentation of clinical forensic data using anonymous and person-specific 3D reference manikins.

    Science.gov (United States)

    Urschler, Martin; Höller, Johannes; Bornik, Alexander; Paul, Tobias; Giretzlehner, Michael; Bischof, Horst; Yen, Kathrin; Scheurer, Eva

    2014-08-01

    The increasing use of CT/MR devices in forensic analysis motivates the need to present forensic findings from different sources in an intuitive reference visualization, with the aim of combining 3D volumetric images along with digital photographs of external findings into a 3D computer graphics model. This model allows a comprehensive presentation of forensic findings in court and enables comparative evaluation studies correlating data sources. The goal of this work was to investigate different methods to generate anonymous and patient-specific 3D models which may be used as reference visualizations. The issue of registering 3D volumetric as well as 2D photographic data to such 3D models is addressed to provide an intuitive context for injury documentation from arbitrary modalities. We present an image processing and visualization work-flow, discuss the major parts of this work-flow, compare the different investigated reference models, and show a number of cases studies that underline the suitability of the proposed work-flow for presenting forensically relevant information in 3D visualizations. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  5. (DArT) markers

    Indian Academy of Sciences (India)

    age groups of both maternal and paternal maps. The segre- gating markers were classified into two classes; for DArT class 1 consensus marker the selection criterion were of very high stringency parameters with clustering settings; Q >. 70; P > 75; call rate > 90, 100% reproducibility, no dis- cordance, and probability > 0.001 ...

  6. Radiopaque anastomosis marker

    International Nuclear Information System (INIS)

    Elliott, D.P.; Halseth, W.L.

    1977-01-01

    This invention relates to split ring markers fabricated in whole or in part from a radiopaque material, usually metal, having the terminal ends thereof and a medial portion formed to define eyelets by means of which said marker can be sutured to the tissue at the site of an anastomosis to provide a visual indication of its location when examined fluoroscopically

  7. Nuclear Medicine

    Science.gov (United States)

    ... Parents/Teachers Resource Links for Students Glossary Nuclear Medicine What is nuclear medicine? What are radioactive tracers? ... funded researchers advancing nuclear medicine? What is nuclear medicine? Nuclear medicine is a medical specialty that uses ...

  8. Preference for anonymity in sperm donation for artificial insemination: an experience from low-resource settings in Nigeria

    Directory of Open Access Journals (Sweden)

    Ezugwu EC

    2018-04-01

    Full Text Available Euzebus Chinonye Ezugwu,1,2 George U Eleje,3,4 Chukwuemeka A Iyoke,1,2 Sunday G Mba,5 Henry C Nnaji,2 Chukwunonso I Enechukwu,4 Peter O Nkwo1,2 1Department of Obstetrics and Gynecology, Faculty of Medical Sciences, College of Medicine, University of Nigeria, Ittuku Ozalla Campus, Enugu State, Nigeria; 2Department of Obstetrics and Gynecology, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu State, Nigeria; 3Department of Obstetrics and Gynecology, Faculty of Medicine, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria; 4Department of Obstetrics and Gynecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, Nigeria; 5Department of Obstetrics and Gynecology, Enugu State University Teaching Hospital, Enugu State, Nigeria Objective: Anonymous sperm donation is a common practice in Nigeria with its associated legal and ethical challenges. This study aimed to investigate infertile couples’ opinions about issues of sperm donor anonymity and to determine factors that might influence their preferences.Methods: A cross-sectional, multicentered, questionnaire-based study was conducted among infertile couples attending infertility clinics in three tertiary hospitals in the south-eastern region of Nigeria over a period of 6 months.Results: A total of 450 infertile couples were recruited consecutively from the three study centers. However, 450 females and 352 males (total=802 participated in the study. The level of awareness of artificial insemination using donor sperm for the management of male infertility among the respondents was 69.2%, while its acceptability rate was 62.7%. The majority of the respondents indicated their preference for secrecy and anonymity in sperm donation. Approximately 84% of the respondents indicated that the mode of conception should never be disclosed to the donor-conceived child, and ~92% of them indicated that the identity of the sperm donor should never be revealed to the donor

  9. Anonymity Preserving Routing In Location Privacy Schemes In Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    R Regin

    2015-12-01

    Full Text Available Location privacy measures need to be developed to prevent the opponent from determining the physical locations of source sensors and sinks. An opponent can easily intercept network traffic due to the use of a broadcast medium for routing packets and get detailed information such as packet transmission time and frequency to perform traffic analysis and infer the locations of monitored objects and data sinks. On the other hand, sensors usually have limited processing speed and energy supplies. It is very expensive to apply traditional anonymous communication techniques for hiding the communication between sensor nodes and sinks. The existing source-location privacy protects the location of monitored objects to increase the number of messages sent by the source before the object is located by the attacker. The flooding technique has the source node send each packet through numerous paths to a sink making it difficult for an opponent to trace the source. The locations of sinks can be protected from a local eavesdropper by hashing the ID field in the packet header. But opponent can track sinks by carrying out time correlation and rate monitoring attacks. Besides protection some source nodes are transferring relatively large amounts of data in existing system. As a result, these nodes run out of battery faster due to improper position of nodes and sinks. Thus in the proposed system the sinks should be located as optimally as possible to reduce traffic flow and energy consumption for sensor nodes. Hence Sink placement problem is resolved for minimizing the delay as well as maximizing the lifetime of a WSN. Thus proposed system is efficient in terms of overhead and functionality when compared to existing system.

  10. Anonymous authentication and location privacy preserving schemes for LTE-A networks

    Directory of Open Access Journals (Sweden)

    Zaher Jabr Haddad

    2017-11-01

    Full Text Available Long Term Evaluation Advanced (LTE-A is the third generation partnership project for cellular network that allows subscribers to roam into networks (i.e., the Internet and wireless connections using spacial purpose base-stations, such as wireless access points and home node B. In such LTE-A based networks, neither base-stations, nor the Internet and wireless connections are trusted because base-stations are operated by un-trusted subscribers. Attackers may exploit these vulnerabilities to violate the privacy of the LTE-A subscribers. On the other hand, the tradeoff between privacy and authentication is another challenge in such networks. Therefore, in this paper, we propose two anonymous authentication schemes based on one-time pseudonymes and Schnorr Zero Knowledge Protocols. Instead of the international mobile subscriber identity, these schemes enable the user equipment, base-stations and mobility management entity to mutually authenticate each others and update the location of the user equipment without evolving the home subscriber server. The security analysis demonstrate that the proposed schemes thwart security and privacy attacks, such as malicious, international mobile subscriber identity catching, and tracking attacks. Additionally, our proposed schemes preserve the location privacy of user equipment since no entity except the mobility management entity and Gate-Way Mobile Location Center can link between the pseudonymes and the international mobile subscriber identity. Also attackers have no knowledge about international mobile subscriber identity. Hence, the proposed schemes achieve backward/forward secrecy. Furthermore, the performance evaluation shows that the proposed handover schemes impose a small overhead on the mobile nodes and it has smaller computation and communication overheads than those in other schemes.

  11. A robust anonymous biometric-based remote user authentication scheme using smart cards

    Directory of Open Access Journals (Sweden)

    Ashok Kumar Das

    2015-04-01

    Full Text Available Several biometric-based remote user authentication schemes using smart cards have been proposed in the literature in order to improve the security weaknesses in user authentication system. In 2012, An proposed an enhanced biometric-based remote user authentication scheme using smart cards. It was claimed that the proposed scheme is secure against the user impersonation attack, the server masquerading attack, the password guessing attack, and the insider attack and provides mutual authentication between the user and the server. In this paper, we first analyze the security of An’s scheme and we show that this scheme has three serious security flaws in the design of the scheme: (i flaw in user’s biometric verification during the login phase, (ii flaw in user’s password verification during the login and authentication phases, and (iii flaw in user’s password change locally at any time by the user. Due to these security flaws, An’s scheme cannot support mutual authentication between the user and the server. Further, we show that An’s scheme cannot prevent insider attack. In order to remedy the security weaknesses found in An’s scheme, we propose a new robust and secure anonymous biometric-based remote user authentication scheme using smart cards. Through the informal and formal security analysis, we show that our scheme is secure against all possible known attacks including the attacks found in An’s scheme. The simulation results of our scheme using the widely-accepted AVISPA (Automated Validation of Internet Security Protocols and Applications tool ensure that our scheme is secure against passive and active attacks. In addition, our scheme is also comparable in terms of the communication and computational overheads with An’s scheme and other related existing schemes. As a result, our scheme is more appropriate for practical applications compared to other approaches.

  12. Invisible nuclear; converting nuclear

    International Nuclear Information System (INIS)

    Park, Jongmoon

    1993-03-01

    This book consists of 14 chapters which are CNN era and big science, from East and West to North and South, illusory nuclear strategy, UN and nuclear arms reduction, management of armaments, advent of petroleum period, the track of nuclear power generation, view of energy, internationalization of environment, the war over water in the Middle East, influence of radiation and an isotope technology transfer and transfer armament into civilian industry, the end of nuclear period and the nuclear Nonproliferation, national scientific and technological power and political organ and executive organ.

  13. Current status and features of the T-2 Nuclear Information Service

    International Nuclear Information System (INIS)

    MacFarlane, R.E.

    1998-01-01

    This service is run by Group T-2 (Nuclear Theory and Applications) of the Theoretical Division of the Los Alamos National Laboratory, which is operated by the University of California for the US Department of Energy. The author works on nuclear modeling, nuclear data, cross sections, nuclear masses, ENDF, NJOY data processing, nuclear astrophysics, radioactivity, radiation shielding, data for medical radiotherapy, data for high-energy accelerator applications, data and codes for fission and fusion systems, and more. For an introduction to the field of nuclear data and his site, take his Guided Tour. Much of this information can also be accessed using anonymous ftp t2.lanl.gov

  14. Preserving Smart Objects Privacy through Anonymous and Accountable Access Control for a M2M-Enabled Internet of Things

    Directory of Open Access Journals (Sweden)

    José L. Hernández-Ramos

    2015-07-01

    Full Text Available As we get into the Internet of Things era, security and privacy concerns remain as the main obstacles in the development of innovative and valuable services to be exploited by society. Given the Machine-to-Machine (M2M nature of these emerging scenarios, the application of current privacy-friendly technologies needs to be reconsidered and adapted to be deployed in such global ecosystem. This work proposes different privacy-preserving mechanisms through the application of anonymous credential systems and certificateless public key cryptography. The resulting alternatives are intended to enable an anonymous and accountable access control approach to be deployed on large-scale scenarios, such as Smart Cities. Furthermore, the proposed mechanisms have been deployed on constrained devices, in order to assess their suitability for a secure and privacy-preserving M2M-enabled Internet of Things.

  15. Analysis of Drugs of Abuse in Anonymously Collected Urine and Soil samples from a Music Festival in Scandinavia

    DEFF Research Database (Denmark)

    Mardal, Marie; Ramin, Pedram; Plósz, Benedek G.

    and urine samples were also prepared by adding acetonitrile, shaking, centrifugation, and evaporation. Extracts were then analyzed by UHPLC-MSn (TF LXQ), UHPLC-HRMS/MS (TF Q-Exactive), and GC-MS (TF ISQ). Urine samples were additionally tested for 9-carboxy-THC by immunoassay and ethanol by headspace GC......Aim: Pooled human urine and soil from urinating spots were collected anonymously at a Scandinavian music festival. Samples should be screened for drugs of abuse, particularly novel psychoactive substances (NPS), but also therapeutic drugs and ethanol. Methods: Twenty-one urine samples were...... collected anonymously from urinal and HMMA-d3 and trimipramin-d3 were added as internal standards. Additionally, 12 soil samples were collected near fences where people urinated. Urine samples were processed by enzymatic conjugate cleavage, SPE (HCX and C18), and acetylation prior to GC-MS. Soil samples...

  16. Preserving Smart Objects Privacy through Anonymous and Accountable Access Control for a M2M-Enabled Internet of Things.

    Science.gov (United States)

    Hernández-Ramos, José L; Bernabe, Jorge Bernal; Moreno, M Victoria; Skarmeta, Antonio F

    2015-07-01

    As we get into the Internet of Things era, security and privacy concerns remain as the main obstacles in the development of innovative and valuable services to be exploited by society. Given the Machine-to-Machine (M2M) nature of these emerging scenarios, the application of current privacy-friendly technologies needs to be reconsidered and adapted to be deployed in such global ecosystem. This work proposes different privacy-preserving mechanisms through the application of anonymous credential systems and certificateless public key cryptography. The resulting alternatives are intended to enable an anonymous and accountable access control approach to be deployed on large-scale scenarios, such as Smart Cities. Furthermore, the proposed mechanisms have been deployed on constrained devices, in order to assess their suitability for a secure and privacy-preserving M2M-enabled Internet of Things.

  17. More than addiction: Examining the role of anonymity, endless narrative, and socialization in prolonged gaming and instant messaging practices

    Directory of Open Access Journals (Sweden)

    Kishonna Gray

    2015-06-01

    Full Text Available This ethnographic study explores a user’s prolonged engagement within virtual gaming communities. Likening prolonged engagement with addiction, this research provides an alternative perspective into virtual addiction focusing on three interrelated themes: 1 anonymity, 2 endless narrative, and 3 socialization. By employing narrative interviews and virtual observations, the researchers examine two different cultural, racial and age groups’ user experience within console and computer-based multiplayer environments. More specifically, they explore how the three factors (i.e., anonymity; endless narrative; socialization relate to the prolonged and extended use within these virtual communities and highlight the multifaceted uses of traditional chat services, social media, and the convergence of media existing within these chat communities.

  18. Simple Algorithms for Distributed Leader Election in Anonymous Synchronous Rings and Complete Networks Inspired by Neural Development in Fruit Flies.

    Science.gov (United States)

    Xu, Lei; Jeavons, Peter

    2015-11-01

    Leader election in anonymous rings and complete networks is a very practical problem in distributed computing. Previous algorithms for this problem are generally designed for a classical message passing model where complex messages are exchanged. However, the need to send and receive complex messages makes such algorithms less practical for some real applications. We present some simple synchronous algorithms for distributed leader election in anonymous rings and complete networks that are inspired by the development of the neural system of the fruit fly. Our leader election algorithms all assume that only one-bit messages are broadcast by nodes in the network and processors are only able to distinguish between silence and the arrival of one or more messages. These restrictions allow implementations to use a simpler message-passing architecture. Even with these harsh restrictions our algorithms are shown to achieve good time and message complexity both analytically and experimentally.

  19. Efficacy of molecular markers jnurf13 and AcPms1 for prediction of genotypes at the nuclear Ms locus in North American open-pollinated populations of onion

    Science.gov (United States)

    Seed of hybrid onion (Allium cepa L.) is produced using cytoplasmic male sterility (CMS) and the for most widely used source of onion CMS, male sterility is conditioned by the interaction of male-sterile (S) cytoplasm and the homozygous recessive genotype at the nuclear male-fertility locus Ms. Due ...

  20. AN EFFECTIVE MULTI-CLUSTERING ANONYMIZATION APPROACH USING DISCRETE COMPONENT TASK FOR NON-BINARY HIGH DIMENSIONAL DATA SPACES

    Directory of Open Access Journals (Sweden)

    L.V. Arun Shalin

    2016-01-01

    Full Text Available Clustering is a process of grouping elements together, designed in such a way that the elements assigned to similar data points in a cluster are more comparable to each other than the remaining data points in a cluster. During clustering certain difficulties related when dealing with high dimensional data are ubiquitous and abundant. Works concentrated using anonymization method for high dimensional data spaces failed to address the problem related to dimensionality reduction during the inclusion of non-binary databases. In this work we study methods for dimensionality reduction for non-binary database. By analyzing the behavior of dimensionality reduction for non-binary database, results in performance improvement with the help of tag based feature. An effective multi-clustering anonymization approach called Discrete Component Task Specific Multi-Clustering (DCTSM is presented for dimensionality reduction on non-binary database. To start with we present the analysis of attribute in the non-binary database and cluster projection identifies the sparseness degree of dimensions. Additionally with the quantum distribution on multi-cluster dimension, the solution for relevancy of attribute and redundancy on non-binary data spaces is provided resulting in performance improvement on the basis of tag based feature. Multi-clustering tag based feature reduction extracts individual features and are correspondingly replaced by the equivalent feature clusters (i.e. tag clusters. During training, the DCTSM approach uses multi-clusters instead of individual tag features and then during decoding individual features is replaced by corresponding multi-clusters. To measure the effectiveness of the method, experiments are conducted on existing anonymization method for high dimensional data spaces and compared with the DCTSM approach using Statlog German Credit Data Set. Improved tag feature extraction and minimum error rate compared to conventional anonymization

  1. VT Roadside Historic Markers

    Data.gov (United States)

    Vermont Center for Geographic Information — Roadside Historic Site Marker program has proven an effective way to commemorate Vermont’s many people, events, and places of regional, statewide, or national...

  2. An Extended Chaotic Maps-Based Three-Party Password-Authenticated Key Agreement with User Anonymity.

    Science.gov (United States)

    Lu, Yanrong; Li, Lixiang; Zhang, Hao; Yang, Yixian

    2016-01-01

    User anonymity is one of the key security features of an authenticated key agreement especially for communicating messages via an insecure network. Owing to the better properties and higher performance of chaotic theory, the chaotic maps have been introduced into the security schemes, and hence numerous key agreement schemes have been put forward under chaotic-maps. Recently, Xie et al. released an enhanced scheme under Farash et al.'s scheme and claimed their improvements could withstand the security loopholes pointed out in the scheme of Farash et al., i.e., resistance to the off-line password guessing and user impersonation attacks. Nevertheless, through our careful analysis, the improvements were released by Xie et al. still could not solve the problems troubled in Farash et al‥ Besides, Xie et al.'s improvements failed to achieve the user anonymity and the session key security. With the purpose of eliminating the security risks of the scheme of Xie et al., we design an anonymous password-based three-party authenticated key agreement under chaotic maps. Both the formal analysis and the formal security verification using AVISPA are presented. Also, BAN logic is used to show the correctness of the enhancements. Furthermore, we also demonstrate that the design thwarts most of the common attacks. We also make a comparison between the recent chaotic-maps based schemes and our enhancements in terms of performance.

  3. An Extended Chaotic Maps-Based Three-Party Password-Authenticated Key Agreement with User Anonymity.

    Directory of Open Access Journals (Sweden)

    Yanrong Lu

    Full Text Available User anonymity is one of the key security features of an authenticated key agreement especially for communicating messages via an insecure network. Owing to the better properties and higher performance of chaotic theory, the chaotic maps have been introduced into the security schemes, and hence numerous key agreement schemes have been put forward under chaotic-maps. Recently, Xie et al. released an enhanced scheme under Farash et al.'s scheme and claimed their improvements could withstand the security loopholes pointed out in the scheme of Farash et al., i.e., resistance to the off-line password guessing and user impersonation attacks. Nevertheless, through our careful analysis, the improvements were released by Xie et al. still could not solve the problems troubled in Farash et al‥ Besides, Xie et al.'s improvements failed to achieve the user anonymity and the session key security. With the purpose of eliminating the security risks of the scheme of Xie et al., we design an anonymous password-based three-party authenticated key agreement under chaotic maps. Both the formal analysis and the formal security verification using AVISPA are presented. Also, BAN logic is used to show the correctness of the enhancements. Furthermore, we also demonstrate that the design thwarts most of the common attacks. We also make a comparison between the recent chaotic-maps based schemes and our enhancements in terms of performance.

  4. Latent Feature Models for Uncovering Human Mobility Patterns from Anonymized User Location Traces with Metadata

    KAUST Repository

    Alharbi, Basma Mohammed

    2017-04-10

    In the mobile era, data capturing individuals’ locations have become unprecedentedly available. Data from Location-Based Social Networks is one example of large-scale user-location data. Such data provide a valuable source for understanding patterns governing human mobility, and thus enable a wide range of research. However, mining and utilizing raw user-location data is a challenging task. This is mainly due to the sparsity of data (at the user level), the imbalance of data with power-law users and locations check-ins degree (at the global level), and more importantly the lack of a uniform low-dimensional feature space describing users. Three latent feature models are proposed in this dissertation. Each proposed model takes as an input a collection of user-location check-ins, and outputs a new representation space for users and locations respectively. To avoid invading users privacy, the proposed models are designed to learn from anonymized location data where only IDs - not geophysical positioning or category - of locations are utilized. To enrich the inferred mobility patterns, the proposed models incorporate metadata, often associated with user-location data, into the inference process. In this dissertation, two types of metadata are utilized to enrich the inferred patterns, timestamps and social ties. Time adds context to the inferred patterns, while social ties amplifies incomplete user-location check-ins. The first proposed model incorporates timestamps by learning from collections of users’ locations sharing the same discretized time. The second proposed model also incorporates time into the learning model, yet takes a further step by considering time at different scales (hour of a day, day of a week, month, and so on). This change in modeling time allows for capturing meaningful patterns over different times scales. The last proposed model incorporates social ties into the learning process to compensate for inactive users who contribute a large volume

  5. Online social network data as sociometric markers.

    Science.gov (United States)

    Binder, Jens F; Buglass, Sarah L; Betts, Lucy R; Underwood, Jean D M

    2017-10-01

    Data from online social networks carry enormous potential for psychological research, yet their use and the ethical implications thereof are currently hotly debated. The present work aims to outline in detail the unique information richness of this data type and, in doing so, to support researchers when deciding on ethically appropriate ways of collecting, storing, publishing, and sharing data from online sources. Focusing on the very nature of social networks, their structural characteristics, and depth of information, we provide a detailed and accessible account of the challenges associated with data management and data storage. In particular, the general nonanonymity of network data sets is discussed, and an approach is developed to quantify the level of uniqueness that a particular online network bestows upon the individual maintaining it. Using graph enumeration techniques, we show that comparatively sparse information on a network is suitable as a sociometric marker that allows for the identification of an individual from the global population of online users. The impossibility of anonymizing specific types of network data carries implications for ethical guidelines and research practice. At the same time, network uniqueness opens up opportunities for novel research in psychology. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  6. Nuclear liability - nuclear insurance

    International Nuclear Information System (INIS)

    Roesch, H.

    1981-01-01

    In the fourth concluding article on this subject (following articles in VW 1981 pp. 483, 552 and 629), the author explains procedures, duties and obligations according to the Para. Para. 5, 6 and 7 of the AHBKA. These obligations are to be observed before or after the occurrence of damages. In addition, legal consequences following violations of duties - loss of right - joint, insurance, transfer ban, period for filing suit, duty to notify, 'The German Nuclear Reactor Insurance and Reinsurance Community', the insurance according to the 'General terms and conditions governing the liability insurance of licensed activities involving nuclear fuels and other radioactive substances outside nuclear installations (AHBStr.)', object, beginning and exclusion of coverage, 'Special conditions governing the transport of nuclear fuels according to Para. 25 (2) of the Atomic Energy Law' are attached to the General Terms and Conditions governing the liability insurance of licenced activities involving nuclear fuels and other radioactive substances outside nuclear installations. (HSCH) [de

  7. Enhanced cross-species utility of conserved microsatellite markers in shorebirds

    Directory of Open Access Journals (Sweden)

    Székely Tamás

    2008-10-01

    Full Text Available Abstract Background Microsatellite markers are popular genetic markers frequently used in forensic biology. Despite their popularity, the characterisation of polymorphic microsatellite loci and development of suitable markers takes considerable effort. Newly-available genomic databases make it feasible to identify conserved genetic markers. We examined the utility and characteristics of conserved microsatellite markers in Charadriiformes (plovers, sandpipers, gulls and auks. This order harbours many species with diverse breeding systems, life histories and extraordinary migration biology whose genetics warrant investigation. However, research has been largely restrained by the limited availability of genetic markers. To examine the utility of conserved microsatellite loci as genetic markers we collated a database of Charadriiformes microsatellites, searched for homologues in the chicken genome and tested conserved markers for amplification and polymorphism in a range of charadriiform species. Results Sixty-eight (42% of 161 charadriiform microsatellite loci were assigned to a single location in the chicken genome based on their E-value. Fifty-five primers designed from conserved microsatellite loci with an E-value of E-10 or lower amplified across a wider range of charadriiform species than a control group of primers from ten anonymous microsatellite loci. Twenty-three of 24 examined conserved markers were polymorphic, each in on average 3 of 12 species tested. Conclusion Genomic sequence databases are useful tools to identify conserved genetic markers including those located in non-coding regions. By maximising primer sequence similarity between source species and database species, markers can be further improved and provide additional markers to study the molecular ecology of populations of non-model organisms.

  8. Comparison of tumor markers using different detection devices

    OpenAIRE

    Tao, Rong; Tu, Shaohua; Liu, Chong; Yang, Qi; Zhu, Min; Shen, Jiangfan

    2015-01-01

    This paper has been retracted  Rong Tao, Shaohua Tu, Chong Liu, Qi Yang, Min Zhu, Jiangfan Shen Nuclear Medicine, Putuo District Center Hospital, Shanghai, People’s Republic of China Background: With the development of proteomics, tumor markers have attracted increasing attention for the early diagnosis and treatment of lung cancer. As biochip technology and nanotechnology continues to grow, rapid and highly sensitive joint detection of multi-tumor markers has beco...

  9. [Nuclear theory

    International Nuclear Information System (INIS)

    Haxton, W.

    1990-01-01

    This report discusses research in nuclear physics. Topics covered in this paper are: symmetry principles; nuclear astrophysics; nuclear structure; quark-gluon plasma; quantum chromodynamics; symmetry breaking; nuclear deformation; and cold fusion

  10. Tumour markers in urology

    International Nuclear Information System (INIS)

    Schmid, L.; Fornara, P.; Fabricius, P.G.

    1988-01-01

    The same applies essentially also for the bladder carcinomas: There is no reliable marker for these cancers which would be useful for clinical purposes. TPA has proven to be too non-specific in malignoma-detection and therefore hardly facilitates clinical decision-making in individual cases. The CEA is not sensitive enough to be recommendable for routine application. However, in advanced stages a CEA examination may be useful if applied within the scope of therapeutic efforts made to evaluate efficacy. In cases of carcinomas of the prostate the sour prostate-specific phosphatase (SPP) and, more recently, especially the prostate-specific antigen (PSA) have proven in follow-up and therapy monitoring, whereby the PSA is superior to the SPP. Nevertheless, both these markers should be employed in therapy monitoring because differences in behaviour will be observed when the desired treatment effect is only achieved in one of the two markers producing tumour cell clonuses. Both markers, but especially the PSA, are quite reliably in agreement with the result of the introduced chemo-/hormone therapy, whereby an increase may be a sure indicator of relapse several months previous to clinical symptoms, imaging procedures, so-called routine laboratory results and subjective complaints. However, none of the 2 markers is appropriate for the purposes of screening or early diagnosis of carcinomas of the prostate. (orig.) [de

  11. Markers of erectile dysfunction

    Directory of Open Access Journals (Sweden)

    Kelvin P Davies

    2008-01-01

    Full Text Available With the development and marketing of oral pharmacotherapy that is both noninvasive and successful in treating erectile dysfunction (ED, the quest to identify markers of organic ED lost ground. Indeed, the multi-factorial nature of ED may have led many researchers to conclude that searching for a universal marker of ED was futile. However, the realization that ED is strongly correlated with the overall health of men, and may act as a predictor for the development of cardiovascular disease (CVD and diabetes, has stimulated interest in identifying genes that can distinguish organic ED. In addition, the potential ability to suggest to the patient that ED is reversible (i.e., psychogenic with a simple test would be of significance to both the physician and patient, as well as for reimbursement issues for therapy by insurance companies. Such a marker may also act as a non-subjective measure of the degree of ED and the efficacy of treatment. This review discusses the importance of identifying such markers and recent work identifying potential markers in human patients.

  12. Genic Microsatellite Markers in Brassica rapa: Development, Characterization, Mapping, and Their Utility in Other Cultivated and Wild Brassica Relatives

    Science.gov (United States)

    Ramchiary, Nirala; Nguyen, Van Dan; Li, Xiaonan; Hong, Chang Pyo; Dhandapani, Vignesh; Choi, Su Ryun; Yu, Ge; Piao, Zhong Yun; Lim, Yong Pyo

    2011-01-01

    Genic microsatellite markers, also known as functional markers, are preferred over anonymous markers as they reveal the variation in transcribed genes among individuals. In this study, we developed a total of 707 expressed sequence tag-derived simple sequence repeat markers (EST-SSRs) and used for development of a high-density integrated map using four individual mapping populations of B. rapa. This map contains a total of 1426 markers, consisting of 306 EST-SSRs, 153 intron polymorphic markers, 395 bacterial artificial chromosome-derived SSRs (BAC-SSRs), and 572 public SSRs and other markers covering a total distance of 1245.9 cM of the B. rapa genome. Analysis of allelic diversity in 24 B. rapa germplasm using 234 mapped EST-SSR markers showed amplification of 2 alleles by majority of EST-SSRs, although amplification of alleles ranging from 2 to 8 was found. Transferability analysis of 167 EST-SSRs in 35 species belonging to cultivated and wild brassica relatives showed 42.51% (Sysimprium leteum) to 100% (B. carinata, B. juncea, and B. napus) amplification. Our newly developed EST-SSRs and high-density linkage map based on highly transferable genic markers would facilitate the molecular mapping of quantitative trait loci and the positional cloning of specific genes, in addition to marker-assisted selection and comparative genomic studies of B. rapa with other related species. PMID:21768136

  13. Novel prognostic tissue markers in congestive heart failure.

    Science.gov (United States)

    Stone, James R

    2015-01-01

    Heart failure is a relatively common disorder associated with high morbidity, mortality, and economic burden. Better tools to predict outcomes for patients with heart failure could allow for better decision making concerning patient treatment and management and better utilization of health care resources. Endomyocardial biopsy offers a mechanism to pathologically diagnose specific diseases in patients with heart failure, but such biopsies can often be negative, with no specific diagnostic information. Novel tissue markers in endomyocardial biopsies have been identified that may be useful in assessing prognosis in heart failure patients. Such tissue markers include ubiquitin, Gremlin-1, cyclophilin A, and heterogeneous nuclear ribonucleoprotein C. In some cases, tissue markers have been found to be independent of and even superior to clinical indices and serum markers in predicting prognosis for heart failure patients. In some cases, these novel tissue markers appear to offer prognostic information even in the setting of an otherwise negative endomyocardial biopsy. Copyright © 2014 Elsevier Inc. All rights reserved.

  14. [Markers of brain tumors].

    Science.gov (United States)

    Fumagalli, R; Pezzotta, S; Bernini, F; Racagni, G

    1984-05-19

    Biological markers of tumors are compounds or enzymatic activities measurable in body fluids. Their presence or concentration must be linked to tumoral growth. The markers of the central nervous system tumors are detected in CSF. Alpha-feto-protein, carcinoembryonic antigen, human chorionic gonadotropin, adenohypophyseal peptide hormones, enzymes, etc., have found some application in the early diagnosis of leptomeningeal metastasis. Other applications involve the early detection and recurrency of primary brain tumors, as well as the evaluation of efficacy of their therapy. The tests based on the CSF content of desmosterol and polyamines have been studied extensively. Their rationale is discussed and specificity, sensitivity, efficiency and predictive value are considered. Experimental results concerning a new possible biochemical marker, based on CSF concentration of cyclic adenosine monophosphate, are reported.

  15. Nuclear power and nuclear weapons

    International Nuclear Information System (INIS)

    Vaughen, V.C.A.

    1983-01-01

    The proliferation of nuclear weapons and the expanded use of nuclear energy for the production of electricity and other peaceful uses are compared. The difference in technologies associated with nuclear weapons and nuclear power plants are described

  16. A novel on-line spatial-temporal k-anonymity method for location privacy protection from sequence rules-based inference attacks.

    Science.gov (United States)

    Zhang, Haitao; Wu, Chenxue; Chen, Zewei; Liu, Zhao; Zhu, Yunhong

    2017-01-01

    Analyzing large-scale spatial-temporal k-anonymity datasets recorded in location-based service (LBS) application servers can benefit some LBS applications. However, such analyses can allow adversaries to make inference attacks that cannot be handled by spatial-temporal k-anonymity methods or other methods for protecting sensitive knowledge. In response to this challenge, first we defined a destination location prediction attack model based on privacy-sensitive sequence rules mined from large scale anonymity datasets. Then we proposed a novel on-line spatial-temporal k-anonymity method that can resist such inference attacks. Our anti-attack technique generates new anonymity datasets with awareness of privacy-sensitive sequence rules. The new datasets extend the original sequence database of anonymity datasets to hide the privacy-sensitive rules progressively. The process includes two phases: off-line analysis and on-line application. In the off-line phase, sequence rules are mined from an original sequence database of anonymity datasets, and privacy-sensitive sequence rules are developed by correlating privacy-sensitive spatial regions with spatial grid cells among the sequence rules. In the on-line phase, new anonymity datasets are generated upon LBS requests by adopting specific generalization and avoidance principles to hide the privacy-sensitive sequence rules progressively from the extended sequence anonymity datasets database. We conducted extensive experiments to test the performance of the proposed method, and to explore the influence of the parameter K value. The results demonstrated that our proposed approach is faster and more effective for hiding privacy-sensitive sequence rules in terms of hiding sensitive rules ratios to eliminate inference attacks. Our method also had fewer side effects in terms of generating new sensitive rules ratios than the traditional spatial-temporal k-anonymity method, and had basically the same side effects in terms of non

  17. Is cyberbullying worse than traditional bullying? Examining the differential roles of medium, publicity, and anonymity for the perceived severity of bullying.

    Science.gov (United States)

    Sticca, Fabio; Perren, Sonja

    2013-05-01

    Cyberbullying, a modern form of bullying performed using electronic forms of contact (e.g., SMS, MMS, Facebook, YouTube), has been considered as being worse than traditional bullying in its consequences for the victim. This difference was mainly attributed to some specific aspect that are believed to distinguish cyberbullying from traditional bullying: an increased potential for a large audience, an increased potential for anonymous bullying, lower levels of direct feedback, decreased time and space limits, and lower levels of supervision. The present studies investigated the relative importance of medium (traditional vs. cyber), publicity (public vs. private), and bully's anonymity (anonymous vs. not anonymous) for the perceived severity of hypothetical bullying scenarios among a sample of Swiss seventh- and eight-graders (study 1: 49% female, mean age = 13.7; study 2: 49% female, mean age = 14.2). Participants ranked a set of hypothetical bullying scenarios from the most severe one to the least severe one. The scenarios were experimentally manipulated based on the aspect of medium and publicity (study 1), and medium and anonymity (study 2). Results showed that public scenarios were perceived as worse than private ones, and that anonymous scenarios were perceived as worse than not anonymous ones. Cyber scenarios generally were perceived as worse than traditional ones, although effect sizes were found to be small. These results suggest that the role of medium is secondary to the role of publicity and anonymity when it comes to evaluating bullying severity. Therefore, cyberbullying is not a priori perceived as worse than traditional bullying. Implications of the results for cyberbullying prevention and intervention are discussed.

  18. An Approach to Reducing Information Loss and Achieving Diversity of Sensitive Attributes in k-anonymity Methods.

    Science.gov (United States)

    Yoo, Sunyong; Shin, Moonshik; Lee, Doheon

    2012-11-13

    Electronic Health Records (EHRs) enable the sharing of patients' medical data. Since EHRs include patients' private data, access by researchers is restricted. Therefore k-anonymity is necessary to keep patients' private data safe without damaging useful medical information. However, k-anonymity cannot prevent sensitive attribute disclosure. An alternative, l-diversity, has been proposed as a solution to this problem and is defined as: each Q-block (ie, each set of rows corresponding to the same value for identifiers) contains at least l well-represented values for each sensitive attribute. While l-diversity protects against sensitive attribute disclosure, it is limited in that it focuses only on diversifying sensitive attributes. The aim of the study is to develop a k-anonymity method that not only minimizes information loss but also achieves diversity of the sensitive attribute. This paper proposes a new privacy protection method that uses conditional entropy and mutual information. This method considers both information loss as well as diversity of sensitive attributes. Conditional entropy can measure the information loss by generalization, and mutual information is used to achieve the diversity of sensitive attributes. This method can offer appropriate Q-blocks for generalization. We used the adult database from the UCI Machine Learning Repository and found that the proposed method can greatly reduce information loss compared with a recent l-diversity study. It can also achieve the diversity of sensitive attributes by counting the number of Q-blocks that have leaks of diversity. This study provides a privacy protection method that can improve data utility and protect against sensitive attribute disclosure. The method is viable and should be of interest for further privacy protection in EHR applications.

  19. Use of pooling and outpatient laboratory specimens in an anonymous seroprevalence survey of HIV infection in British Columbia, Canada.

    Science.gov (United States)

    Sherlock, C H; Strathdee, S A; Le, T; Sutherland, D; O'Shaughnessy, M V; Schechter, M T

    1995-08-01

    To conduct an anonymous HIV seroprevalence survey to establish a baseline estimate of HIV seroprevalence in a general population; to evaluate serum pooling and alternative testing strategies as cost-saving measures. Prospective anonymous HIV seroprevalence study using outpatient laboratory specimens. Two large non-hospital-associated outpatient chemistry testing laboratories in the major population centers in British Columbia, Canada. PATIENTS AND SERA: Leftover sera received for chemistry screen testing in outpatient laboratories were provided to the study after chemistry testing was completed. Those from patients aged or = 55 years were excluded. Patient identifiers were erased from samples. Sera were pooled 10:1 and tested by viral lysate enzyme-linked immunosorbent assay (ELISA). Sera from HIV-positive pools were tested individually. All individual HIV-positive specimens were retested for verification of positivity using a recombinant protein ELISA. HIV seroprevalence rates were stratified by sex, age group, and geographic area; and costs of pooling and alternative algorithm strategy were compared with those of conventional methods. A total of 80,238 sera were collected from 66,658 individuals (53% women, 47% men). Of these, 276 men (88.3 per 10,000) and 24 women (6.8 per 10,000) were HIV-seropositive. The highest rates were in those aged 30-34 years, for both men and women. Using pooling and non-Western blot verification saved US$2.07 per specimen, or 80% of the cost for conventional testing. The anonymous outpatient laboratory setting is practicable to obtain a reasonable estimate of HIV seroprevalence rates in a general population. Such studies can be made cost-effective by pooling sera and using alternative confirmatory strategies.

  20. Analysis of morphological markers of chromosomal instability in ascitic fluid.

    Science.gov (United States)

    Tyagi, Ruchita; Dey, Pranab; Uppal, Radha; Rajwanshi, Arvind

    2015-10-01

    Chromosomal instability (CI) plays a major role in the carcinogenesis. Micronuclei, nuclear budding, chromatin bridges,and multipolar mitoses are the morphological markers of CI and have never been studied in routine cytological specimens. Aims of the study is to analyze the significance of morphological markers of CI in malignant and benign ascitic fluid smears. A total of sixty benign and 40 malignant ascitic fluid samples were selected for this study. All the cases with malignant ascitic fluid showed histopathological evidence of malignancy in ovary and omentum. Chromatin bridges, multipolar mitosis (MPM), micronuclei and nuclear budding were counted in 1000 cells in representative May Grunwald Giemsa (MGG) stained smears. The CI markers were correlated with the cytological diagnosis of effusion. The mean number of micronuclei, nuclear budding, chromatin bridge and multipolar mitoses found in malignant effusions were 13.2611.79, 10.1067.07, 2.5362.67, 1.964.5, respectively. The mean number of micronuclei, nuclear budding, anaphase bridges, and MPM found in benign effusion cases were 0.566761.07934, 0.516761.33, 0.66760.25, and 0, respectively. The student t test showed significant differences between malignant and benign ascitic fluid samples for each marker of CI. This is the first comprehensive study of morphological markers of CI in ascitic fluid smears. This study has shown strong correlation between markers of CI and cytological diagnosis of malignancy. In future, the knowledge of these markers can be applied to diagnose malignancy in suspected cases of effusion in difficult situations. © 2015 Wiley Periodicals, Inc.

  1. Using Discharge Abstracts to Evaluate a Regional Perinatal Network: Assessment of the Linkage Procedure of Anonymous Data

    Science.gov (United States)

    Quantin, Catherine; Gouyon, Béatrice; Avillach, Paul; Ferdynus, Cyril; Sagot, Paul; Gouyon, Jean-Bernard

    2009-01-01

    To assess the Burgundy perinatal network (18 obstetrical units; 18 500 births per year), discharge abstracts and additional data were collected for all mothers and newborns. In accordance with French law, data were rendered anonymous before statistical analysis, and were linked to patients using a specific procedure. This procedure allowed data concerning each mother to be linked to those for her newborn(s). This study showed that all mothers and newborns were included in the regional database; the data for all mothers were linked to those for their infant(s) in all cases. Additional data (gestational age) were obtained for 99.9% of newborns. PMID:19125196

  2. Using Discharge Abstracts to Evaluate a Regional Perinatal Network: Assessment of the Linkage Procedure of Anonymous Data

    Directory of Open Access Journals (Sweden)

    Catherine Quantin

    2009-01-01

    Full Text Available To assess the Burgundy perinatal network (18 obstetrical units; 18 500 births per year, discharge abstracts and additional data were collected for all mothers and newborns. In accordance with French law, data were rendered anonymous before statistical analysis, and were linked to patients using a specific procedure. This procedure allowed data concerning each mother to be linked to those for her newborn(s. This study showed that all mothers and newborns were included in the regional database; the data for all mothers were linked to those for their infant(s in all cases. Additional data (gestational age were obtained for 99.9% of newborns.

  3. [Preliminary results of an anonymous internet-based reporting system for critical incidents in ambulatory primary care].

    Science.gov (United States)

    Brun, A

    2005-03-01

    To learn from errors is not always easy, especially if they happened to others! This paper describes the organization and management of a critical incident reporting system for primary care physicians in Switzerland and reports about the difficulties and experiences during the first 18 months since the start of the program. It seems to be particularly difficult to enhance the attentiveness of physicians for apparently harmless daily critical incidents and to motivate them to report it even in an anonymous reporting system. As incentives for more intensive participation there are the hope for comments on reported cases by other participants and the expectation that reported errors will be avoided by the readers.

  4. The Incompatibility of Pareto Optimality and Dominant-Strategy Incentive Compatibility in Sufficiently-Anonymous Budget-Constrained Quasilinear Settings

    Directory of Open Access Journals (Sweden)

    Rica Gonen

    2013-11-01

    Full Text Available We analyze the space of deterministic, dominant-strategy incentive compatible, individually rational and Pareto optimal combinatorial auctions. We examine a model with multidimensional types, nonidentical items, private values and quasilinear preferences for the players with one relaxation; the players are subject to publicly-known budget constraints. We show that the space includes dictatorial mechanisms and that if dictatorial mechanisms are ruled out by a natural anonymity property, then an impossibility of design is revealed. The same impossibility naturally extends to other abstract mechanisms with an arbitrary outcome set if one maintains the original assumptions of players with quasilinear utilities, public budgets and nonnegative prices.

  5. (DArT) markers

    Indian Academy of Sciences (India)

    wilt and sterility mosaic disease, etc.) stresses. Despite past. ∗For correspondence. E-mail: r.k.varshney@cgiar.org .... Shi Ying Yang et al. Table 2. Details on 466 polymorphic DArT markers. Female specific. Male specific. Total. 198. 268. Class I. 142. 203. Class II. 27. 16. Others. 29. 49. Mapped. 122. 172. Linkage mapping.

  6. Magik Markers Trehvis

    Index Scriptorium Estoniae

    2008-01-01

    Müra-rock'i viljelevast USA duost Magik Markers (ansambel osaleb režissöör Veiko Õunapuu uue mängufilmi "Püha Tõnu kiusamine" võtetel, kontsert 15. nov. Tartus klubis Trehv, vt. www.magikmarkers.audiosport.org.)

  7. The Swift Turbidity Marker

    Science.gov (United States)

    Omar, Ahmad Fairuz; MatJafri, Mohd Zubir

    2011-01-01

    The Swift Turbidity Marker is an optical instrument developed to measure the level of water turbidity. The components and configuration selected for the system are based on common turbidity meter design concepts but use a simplified methodology to produce rapid turbidity measurements. This work is aimed at high school physics students and is the…

  8. “The Question Exists, but You Don’t Exist With It”: Strategic Anonymity in the Social Lives of Adolescents

    Directory of Open Access Journals (Sweden)

    Nicole B. Ellison

    2016-10-01

    Full Text Available Anonymous interactions may have important implications for adolescents’ social and psychological development. In this article, we use semi-structured interview data collected from US adolescents aged 13–18 years ( N  = 22 to explore how the specific affordances of an online platform that enables selective anonymity shape adolescents’ practices and perceptions. We contribute to scholarship on the effects of anonymous interaction online by surfacing positive outcomes for young adults who choose to interact in anonymous contexts—specifically, a question-and-answer site popular with teenagers ( Ask.fm —and explicating the ways in which these interactions assist in key developmental tasks during adolescence. We identify five primary themes: (1 perceived authenticity, (2 circumventing social expectations, (3 learning about the self, (4 managing identity and self-presentation, and (5 initiating and developing relationships. Across these themes, we find that users strategically employ anonymity to achieve their social goals. Use of the site was often deeply embedded in offline social structures, such that the platform was used to circumvent rigid norms around socialization (who can talk to whom and information-seeking (who can ask what, enforced in educational institutions and elsewhere. We conclude that the strategic use of selective anonymity has the potential to scaffold social processes through which adolescents work toward critical developmental goals.

  9. Nuclear rights - nuclear wrongs

    Energy Technology Data Exchange (ETDEWEB)

    Paul, E.F.; Miller, F.D.; Paul, J.; Ahrens, J.

    1986-01-01

    This book contains 11 selections. The titles are: Three Ways to Kill Innocent Bystanders: Some Conundrums Concerning the Morality of War; The International Defense of Liberty; Two Concepts of Deterrence; Nuclear Deterrence and Arms Control; Ethical Issues for the 1980s; The Moral Status of Nuclear Deterrent Threats; Optimal Deterrence; Morality and Paradoxical Deterrence; Immoral Risks: A Deontological Critique of Nuclear Deterrence; No War Without Dictatorship, No Peace Without Democracy: Foreign Policy as Domestic Politics; Marxism-Leninism and its Strategic Implications for the United States; Tocqueveille War.

  10. Nuclear moments

    CERN Document Server

    Kopferman, H; Massey, H S W

    1958-01-01

    Nuclear Moments focuses on the processes, methodologies, reactions, and transformations of molecules and atoms, including magnetic resonance and nuclear moments. The book first offers information on nuclear moments in free atoms and molecules, including theoretical foundations of hyperfine structure, isotope shift, spectra of diatomic molecules, and vector model of molecules. The manuscript then takes a look at nuclear moments in liquids and crystals. Discussions focus on nuclear paramagnetic and magnetic resonance and nuclear quadrupole resonance. The text discusses nuclear moments and nucl

  11. Nuclear medicine; La medecine nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Sibille, L. [Hopital Lapeyronie CHU Montpellier, Medecine Nucleaire, 34 - Montpellier (France); Nalda, E.; Collombier, L.; Kotzki, P.O.; Boudousq, V. [CHU de Nimes, Service de Medecine Nucleaire et de biophysique, 30 - Nimes (France)

    2011-05-15

    Nuclear medicine is a medical specialty using the properties of radioactivity. Radioactive markers associated with vectors are used as a tracer or radiopharmaceutical for diagnostic purposes and/or therapy. Since its birth more than half a century ago, it has become essential in the care of many patients, particularly in oncology. After some definitions, this paper presents the main nuclear techniques - imaging for diagnostic, radiopharmaceuticals as therapeutic agents, intra-operative detection, technique of radioimmunoassay - and the future of this field. (authors)

  12. Entre o controle e o ativismo hacker: a ação política dos Anonymous Brasil

    Directory of Open Access Journals (Sweden)

    Murilo Bansi Machado

    Full Text Available Resumo Este trabalho trata da ação política dos Anonymous, principal expressão do ativismo hacker atual, argumentando que o hacktivismo se configura como uma forma de resistência política nas sociedades de controle. Para isso, centra-se no estudo da faceta brasileira e hacktivista do coletivo. A fim de ressaltar seu caráter político, recorre às principais expressões dohacking na literatura. Descreve motivações, métodos e a ética de sua ação política, tendo como base uma análise comparativa de duas operações deflagradas por Anonymous brasileiros em 2012: #OpWeeksPayment e #OpGlobo. Por fim, identifica quatro de suas principais formas de engajamento político: promoção do anonimato; “evangelização”; formação de redes distribuídas; e o fato de o coletivo exibir e possibilitar várias formas de ações políticas.

  13. Anonymization of Court Decisions: Are Restrictions on the Right to Information in “Accordance with the Law”?

    Directory of Open Access Journals (Sweden)

    Gruodytė Edita

    2016-12-01

    Full Text Available In Lithuania rules for the anonymization of court decisions were introduced in 2005. These rules require automatic anonymization of all court decisions, which in the opinion of the authors violates the public interest to know and freedom of expression is unjustifiably restricted on behalf of the right to privacy. This issue covers two diametrically opposed human rights: the right to privacy and the right to information. The first question is how the balance between two equivalent rights could be reached. The second question is whether this regulation is in accordance with the law as it is established in the national Constitution and revealed by the Constitutional Court of the Republic of Lithuania and developed by the jurisprudence of the European Court of Human Rights. The authors conclude that the legislator is not empowered to delegate to the Judicial Council issues which are a matter of legal regulation and suggest possible solutions evaluating practice of the Court of Justice of the European Union, the European Court of Human Rights, and selected EU countries.

  14. Chaotic maps and biometrics-based anonymous three-party authenticated key exchange protocol without using passwords

    Science.gov (United States)

    Xie, Qi; Hu, Bin; Chen, Ke-Fei; Liu, Wen-Hao; Tan, Xiao

    2015-11-01

    In three-party password authenticated key exchange (AKE) protocol, since two users use their passwords to establish a secure session key over an insecure communication channel with the help of the trusted server, such a protocol may suffer the password guessing attacks and the server has to maintain the password table. To eliminate the shortages of password-based AKE protocol, very recently, according to chaotic maps, Lee et al. [2015 Nonlinear Dyn. 79 2485] proposed a first three-party-authenticated key exchange scheme without using passwords, and claimed its security by providing a well-organized BAN logic test. Unfortunately, their protocol cannot resist impersonation attack, which is demonstrated in the present paper. To overcome their security weakness, by using chaotic maps, we propose a biometrics-based anonymous three-party AKE protocol with the same advantages. Further, we use the pi calculus-based formal verification tool ProVerif to show that our AKE protocol achieves authentication, security and anonymity, and an acceptable efficiency. Project supported by the Natural Science Foundation of Zhejiang Province, China (Grant No. LZ12F02005), the Major State Basic Research Development Program of China (Grant No. 2013CB834205), and the National Natural Science Foundation of China (Grant No. 61070153).

  15. An Anonymous User Authentication and Key Agreement Scheme Based on a Symmetric Cryptosystem in Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Jaewook Jung

    2016-08-01

    Full Text Available In wireless sensor networks (WSNs, a registered user can login to the network and use a user authentication protocol to access data collected from the sensor nodes. Since WSNs are typically deployed in unattended environments and sensor nodes have limited resources, many researchers have made considerable efforts to design a secure and efficient user authentication process. Recently, Chen et al. proposed a secure user authentication scheme using symmetric key techniques for WSNs. They claim that their scheme assures high efficiency and security against different types of attacks. After careful analysis, however, we find that Chen et al.’s scheme is still vulnerable to smart card loss attack and is susceptible to denial of service attack, since it is invalid for verification to simply compare an entered ID and a stored ID in smart card. In addition, we also observe that their scheme cannot preserve user anonymity. Furthermore, their scheme cannot quickly detect an incorrect password during login phase, and this flaw wastes both communication and computational overheads. In this paper, we describe how these attacks work, and propose an enhanced anonymous user authentication and key agreement scheme based on a symmetric cryptosystem in WSNs to address all of the aforementioned vulnerabilities in Chen et al.’s scheme. Our analysis shows that the proposed scheme improves the level of security, and is also more efficient relative to other related schemes.

  16. Chaotic maps and biometrics-based anonymous three-party authenticated key exchange protocol without using passwords

    International Nuclear Information System (INIS)

    Xie Qi; Hu Bin; Chen Ke-Fei; Liu Wen-Hao; Tan Xiao

    2015-01-01

    In three-party password authenticated key exchange (AKE) protocol, since two users use their passwords to establish a secure session key over an insecure communication channel with the help of the trusted server, such a protocol may suffer the password guessing attacks and the server has to maintain the password table. To eliminate the shortages of password-based AKE protocol, very recently, according to chaotic maps, Lee et al. [2015 Nonlinear Dyn. 79 2485] proposed a first three-party-authenticated key exchange scheme without using passwords, and claimed its security by providing a well-organized BAN logic test. Unfortunately, their protocol cannot resist impersonation attack, which is demonstrated in the present paper. To overcome their security weakness, by using chaotic maps, we propose a biometrics-based anonymous three-party AKE protocol with the same advantages. Further, we use the pi calculus-based formal verification tool ProVerif to show that our AKE protocol achieves authentication, security and anonymity, and an acceptable efficiency. (paper)

  17. The urine marker test

    DEFF Research Database (Denmark)

    Elbe, Anne-Marie; Jensen, Stine Nylandsted; Elsborg, Peter

    2016-01-01

    BACKGROUND: Urine sample collection for doping control tests is a key component of the World Anti-Doping Agency's fight against doping in sport. However, a substantial number of athletes experience difficulty when having to urinate under supervision. Furthermore, it cannot always be ensured...... that athletes are actually delivering their own urine. A method that can be used to alleviate the negative impact of a supervised urination procedure and which can also identify urine as coming from a specific athlete is the urine marker test. Monodisperse low molecular weight polyethylene glycols (PEGs......) are given orally prior to urination. Urine samples can be traced to the donor by analysis of the PEGs previously given. OBJECTIVE: The objective of this study was to investigate the use of the urine marker during urine doping control testing. METHODS: Two studies investigated athletes' acceptance...

  18. Study of the impact of radionuclides discharges from nuclear industry in the northern Cotentin area on the oyster Crassostrea gigas: expression of cellular stress molecular markers; Etude de l'impact des radionucleides rejetes par les installations nucleaires du Nord Cotentin sur l'huitre creuse Crassostrea gigas: analyse de l'expression de marqueurs moleculaires de stress

    Energy Technology Data Exchange (ETDEWEB)

    Farcy, E

    2006-11-15

    This thesis explores the potential radiological impact of radionuclide discharges from the nuclear industry on the Pacific oyster, Crassostrea gigas. One of the major goals of this research was to identify markers that could be used to monitor the effects of low-level chronic irradiation. We decided to focalize on the expression of stress-induced genes involved in the regulation of cellular stress, focusing on transcription. First, homology cloning was used to identify four new cDNAs encoding stress markers. Then data collected at various sites enabled to evidence that mRNA levels for each of the genes of interest naturally vary to a significant degree, based on individual differences and seasonal factors. Comparing oysters from exposed sites with those from a reference site located on the Atlantic coast did not suggest any relationship between mRNA levels changes and the oysters exposure to liquid radioactive waste from the A.R.E.V.A. reprocessing plant. In the environment, we found that those radionuclide releases resulted in a very small increase in radioactivity in oysters, especially compared with their natural radioactivity. In the laboratory, by exposing the oysters to higher radionuclide concentrations than those found in the environment, we were able to identify two genes as potential candidates for studying the effects of chronic exposure to low doses of ionizing radiations in the oyster: genes encoding MT and MXR. We confirmed that transcriptional induction of these two genes occurs in response to high doses of acute irradiation. Finally, the comparison between environmental results and the laboratory results underlined the complementarity of these two approaches. In particular, it revealed that seasonal variations in mRNA levels probably have a significant effect on the stress response. (author)

  19. Nuclear power

    OpenAIRE

    2005-01-01

    David Waller and Alan McDonald ask whether a nuclear renaissance can be predicted; Judith M. Greenwald discusses keeping the nuclear power option open; Paul Mobbs considers the availability of uranium and the future of nuclear energy.

  20. Nuclear Medicine.

    Science.gov (United States)

    Badawi, Ramsey D.

    2001-01-01

    Describes the use of nuclear medicine techniques in diagnosis and therapy. Describes instrumentation in diagnostic nuclear medicine and predicts future trends in nuclear medicine imaging technology. (Author/MM)

  1. EasyClone-MarkerFree

    DEFF Research Database (Denmark)

    Fabre, Mathew Malcolm Jessop; Jakociunas, Tadas; Stovicek, Vratislav

    2016-01-01

    Saccharomyces cerevisiae is an established industrial host for production of recombinant proteins, fuels and chemicals. To enable stable integration of multiple marker-free overexpression cassettes in the genome of S. cerevisiae, we have developed a vector toolkit EasyClone-MarkerFree. The integr...... standardized genome engineering, and should be of particular interest to researchers working on yeast chassis with limited markers available....

  2. Criminología Informática. Anonymous: ¿justicia cibernética o terrorismo enmascarado?/Informatic Criminology. Anonymous: ¿Cyber Justice or masked terrorism?

    Directory of Open Access Journals (Sweden)

    Daniel Romano Ozcáriz

    2017-08-01

    Full Text Available Desde hace ya una década se viene escuchando las acciones cibernéticas de un grupo de ciberactivistas autodenominado Anonymous, pero ¿qué sabemos realmente de ellos? Ciertamente poco, debido en parte a la anárquica organización que los representa y a la ingente cantidad de bulos y rumores sin confirmar que inundan las redes. En honor a la verdad, es imprescindible hacer una limpieza de información y separar lo que es este grupo realmente de lo que es puro desprestigio o sobrevaloración, y de las mentiras. Para ello analizaremos cinco puntos fundamentales, para una mejor comprensión: su definición, valores, principios, simbología y su historia/acciones más representativas.

  3. [The "secret book" of Dr Friedrich Benjamin Osiander: anonymous births in the Göttingen Accouchierhaus, 1794-1819].

    Science.gov (United States)

    Schlumbohm, Jürgen

    2014-01-01

    The problem of anonymous or confidential deliveries, a subject of current controversy, has a long history. Some maternity hospitals offered the possibility for "clandestine" births as early as the 18th and 19th century. A recently emerged source about the maternity clinic of Göttingen University allows insight into the motives that led to keeping a birth secret and the consequences of such a clandestine birth for mother, father and child. The director of the institution, a professor of obstetrics, wrote case reports on the women, who paid a handsome sum for his help and the in-patient care they received. In return, these women could be admitted under a pseudonym, and thus falsify their child's birth certificate; moreover they were not used as teaching material for medical students and midwife apprentices, whereas "regular" patients had to give their names and, in return for being treated free of charge, be available for teaching purposes. The ten cases that have been painstakingly investigated reveal that the reasons that led the women and men to opt for an anonymous birth were manifold, that they used this offer in different ways and with different consequences. All of these pregnancies were illegitimate, of course. In one case the expectant mother was married. In several cases it would be the father who was married. Most of the women who gave birth secretly seem to have given the professor their actual details and he kept quiet about them--with the exception of one case where he revealed the contents of the case report many years later in an alimony suit. Only one of the men admitted paternity openly, but many revealed their identity implicitly by registering the pregnant woman or by accompanying her to the clinic. If the birth was to be kept secret the child needed to be handed over to foster parents. By paying a lump sum that covered the usual fourteen years of parenting, one mother was able to avoid any later contact with her son. In most cases contact seems

  4. Montreal Accord on Patient-Reported Outcomes (PROs) use series - Paper 9: anonymization and ethics considerations for capturing and sharing patient reported outcomes.

    Science.gov (United States)

    Arbuckle, Luk; Moher, Ester; Bartlett, Susan J; Ahmed, Sara; El Emam, Khaled

    2017-09-01

    Patient-reported outcomes (PROs) are collected with consent for care; however, using the data for any other purpose requires consent for that additional purpose, or the anonymization of the data. Collecting explicit consent to use this data for secondary purposes, before the patient completes a PRO, can also bias the responses. We consider the ethical and security issues related to the collection of data at the point of care or in the population and the aggregation and integration of PRO data with administrative databases to facilitate decision making and comparative effectiveness research. In this article, we describe risk-based anonymization, taking the context of the data release into account, so that we may consider the degree by which the release is considered anonymized. We also consider the ethical use of anonymized data, the anonymization of free-form text, and the secure linking data sets without sharing any personal information. Many good standards and best practices exist for the sharing of health data and could be used as a baseline in the development of a national PRO initiative. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Nuclear Power Safety Reporting System. Final evaluation results

    International Nuclear Information System (INIS)

    Finlayson, F.C.; Newton, R.D.

    1986-02-01

    This document presents the results of a study conducted by the US Nuclear Regulatory Commission of an unobtrusive, voluntary, anonymous third-party managed, nonpunitive human factors data gathering system (the Nuclear power Safety Reporting System - NPSRS) for the nuclear electric power production industry. The data to be gathered by the NPSRS are intended for use in identifying and quantifying the factors that contribute to the occurrence of significant safety incidents involving humans in nuclear power plants. The NPSRS has been designed to encourage participation in the System through guarantees of reporter anonymity provided by a third-party organization that would be responsible for NPSRS management. As additional motivation to reporters for contributing data to the NPSRS, conditional waivers of NRC disciplinary action would be provided to individuals. These conditional waivers of immunity would apply to potential violations of NRC regulations that might be disclosed through reports submitted to the System about inadvertent, noncriminal incidents in nuclear plants. This document summarizes the overall results of the study of the NPSRS concept. In it, a functional description of the NPSRS is presented together with a review and assessment of potential problem areas that might be met if the System were implemented. Conclusions and recommendations resulting from the study are also presented. A companion volume (NUREG/CR-4133, Nuclear Power Safety Reporting System: Implementation and Operational Specifications'') presented in detail the elements, requirements, forms, and procedures for implementing and operating the System. 13 refs

  6. Humility and 12-Step Recovery: A Prolegomenon for the Empirical Investigation of a Cardinal Virtue in Alcoholics Anonymous.

    Science.gov (United States)

    Post, Stephen G; Pagano, Maria E; Lee, Matthew T; Johnson, Byron R

    Alcoholics Anonymous (AA) offers a live stage to study how humility is worn by thousands for another day of sobriety and more freedom from the bondage of self. It has been the coauthors' intent to emphasize the significance of humility as a cardinal virtue across the 12-Step program and as essential to all its key elements. The coauthors have placed this emphasis in the context of a wider theological history of thought as this converged on Bill W. and AA. In addition, the coauthors have offered a constructive developmental interpretation of the 12 Steps that relies on a model of four modulations of humility. Finally, the coauthors have reviewed in brief some approaches to the measurement of humility in this context, and suggest several aims for future research.

  7. A Policy Based Approach for the Management of Web Browser Resources to Prevent Anonymity Attacks in Tor

    Science.gov (United States)

    Navarro-Arribas, Guillermo; Garcia-Alfaro, Joaquin

    Web browsers are becoming the universal interface to reach applications and services related with these systems. Different browsing contexts may be required in order to reach them, e.g., use of VPN tunnels, corporate proxies, anonymisers, etc. By browsing context we mean how the user browsers the Web, including mainly the concrete configuration of its browser. When the context of the browser changes, its security requirements also change. In this work, we present the use of authorisation policies to automatise the process of controlling the resources of a Web browser when its context changes. The objective of our proposal is oriented towards easing the adaptation to the security requirements of the new context and enforce them in the browser without the need for user intervention. We present a concrete application of our work as a plug-in for the adaption of security requirements in Mozilla/Firefox browser when a context of anonymous navigation through the Tor network is enabled.

  8. Exploring gender and identity issues among female adolescent and young adults who connect in an anonymous platform.

    Science.gov (United States)

    Pounders, Kathrynn; Stowers, Kirsten; Wilcox, Gary; Love, Brad; Mackert, Michael

    2017-04-01

    There has been an increased usage of online cancer support groups as a resource for health-related information and social support. This work analyzes message blog posts from an anonymous online support community to better understand issues related to gender and identity among female adolescent and young adults. This work sheds further light into the nuances of gender and identity issues including motherhood and reproductive issues, physical appearance, and romantic relationships. Specifically, findings reveal that female adolescent and young adults experience issues pertaining to infertility, feeling like a bad mom, hair loss, scarring, dating, and intimacy. These findings of this work offer further guidance about how healthcare providers and caregivers can attempt to meet the needs of female adolescent and young adults.

  9. An anonymous survey of psychosomatic medicine fellowship directors regarding breaches of contracts and a proposal for prevention.

    Science.gov (United States)

    Levenson, James L; Bialer, Philip

    2010-01-01

    The authors studied how often applicants accept positions at more than one program, or programs offer positions to applicants who have already signed contracts with other programs. An anonymous survey was distributed to all psychosomatic medicine fellowship program directors. It is fairly common for applicants to sign contracts for fellowship positions and then back out of the contracts. Only one program reported ever knowingly offering a contract to an applicant who had accepted a position elsewhere. Programs are divided over whether there are extenuating circumstances under which it would be acceptable to offer a position to an applicant who has already signed a contract with another program. Guidelines for fellowship programs that do not use the National Resident Match Program can improve the recruitment process.

  10. Determining the relative importance of the mechanisms of behavior change within Alcoholics Anonymous: a multiple mediator analysis.

    Science.gov (United States)

    Kelly, John F; Hoeppner, Bettina; Stout, Robert L; Pagano, Maria

    2012-02-01

    Evidence indicates that Alcoholics Anonymous (AA) participation reduces relapse risk but less is known about the mechanisms through which AA confers this benefit. Initial studies indicate self-efficacy, negative affect, adaptive social networks and spiritual practices are mediators of this effect, but because these have been tested in isolation, their relative importance remains elusive. This study tested multiple mediators simultaneously to help determine the most influential pathways. Prospective, statistically controlled, naturalistic investigation examined the extent to which these previously identified mechanisms mediated AA attendance effects on alcohol outcomes controlling for baseline outcome values, mediators, treatment, and other confounders. Nine clinical sites within the United States. Adults (n = 1726) suffering from alcohol use disorder (AUD) initially enrolled in a randomized study with two arms: aftercare (n = 774); and out-patient (n = 952) comparing three out-patient treatments (Project MATCH). AA attendance during treatment; mediators at 9 months; and outcomes [percentage of days abstinent (PDA) and drinks per drinking day (DDD)] at 15 months. Among out-patients the effect of AA attendance on alcohol outcomes was explained primarily by adaptive social network changes and increases in social abstinence self-efficacy. Among more impaired aftercare patients, in addition to mediation through adaptive network changes and increases in social self-efficacy, AA lead to better outcomes through increasing spirituality/religiosity and by reducing negative affect. The degree to which mediators explained the relationship between AA and outcomes ranged from 43% to 67%. While Alcoholics Anonymous facilitates recovery by mobilizing several processes simultaneously, it is changes in social factors which appear to be of primary importance. © 2011 The Authors, Addiction © 2011 Society for the Study of Addiction.

  11. A secure user anonymity-preserving three-factor remote user authentication scheme for the telecare medicine information systems.

    Science.gov (United States)

    Das, Ashok Kumar

    2015-03-01

    Recent advanced technology enables the telecare medicine information system (TMIS) for the patients to gain the health monitoring facility at home and also to access medical services over the Internet of mobile networks. Several remote user authentication schemes have been proposed in the literature for TMIS. However, most of them are either insecure against various known attacks or they are inefficient. Recently, Tan proposed an efficient user anonymity preserving three-factor authentication scheme for TMIS. In this paper, we show that though Tan's scheme is efficient, it has several security drawbacks such as (1) it fails to provide proper authentication during the login phase, (2) it fails to provide correct updation of password and biometric of a user during the password and biometric update phase, and (3) it fails to protect against replay attack. In addition, Tan's scheme lacks the formal security analysis and verification. Later, Arshad and Nikooghadam also pointed out some security flaws in Tan's scheme and then presented an improvement on Tan's s scheme. However, we show that Arshad and Nikooghadam's scheme is still insecure against the privileged-insider attack through the stolen smart-card attack, and it also lacks the formal security analysis and verification. In order to withstand those security loopholes found in both Tan's scheme, and Arshad and Nikooghadam's scheme, we aim to propose an effective and more secure three-factor remote user authentication scheme for TMIS. Our scheme provides the user anonymity property. Through the rigorous informal and formal security analysis using random oracle models and the widely-accepted AVISPA (Automated Validation of Internet Security Protocols and Applications) tool, we show that our scheme is secure against various known attacks, including the replay and man-in-the-middle attacks. Furthermore, our scheme is also efficient as compared to other related schemes.

  12. Bone Remodelling Markers in Rheumatoid Arthritis

    Directory of Open Access Journals (Sweden)

    Patrice Fardellone

    2014-01-01

    Full Text Available Bone loss in rheumatoid arthritis (RA patients results from chronic inflammation and can lead to osteoporosis and fractures. A few bone remodeling markers have been studied in RA witnessing bone formation (osteocalcin, serum aminoterminal propeptide of type I collagen (PINP, serum carboxyterminal propeptide of type I collagen (ICTP, bone alkaline phosphatase (BAP, osteocalcin (OC, and bone resorption: C-terminal telopeptide of type 1 collagen (I-CTX, N-terminal telopeptide of type 1 collagen (I-NTX, pyridinolines (DPD and PYD, and tartrate-resistant acid phosphatase (TRAP. Bone resorption can be seen either in periarticular bone (demineralization and erosion or in the total skeleton (osteoporosis. Whatever the location, bone resorption results from activation of osteoclasts when the ratio between osteoprotegerin and receptor activator of nuclear factor kappa-B ligand (OPG/RANKL is decreased under influence of various proinflammatory cytokines. Bone remodeling markers also allow physicians to evaluate the effect of drugs used in RA like biologic agents, which reduce inflammation and exert a protecting effect on bone. We will discuss in this review changes in bone markers remodeling in patients with RA treated with biologics.

  13. Nuclear medicine

    International Nuclear Information System (INIS)

    Lentle, B.C.

    1986-01-01

    Several growth areas for nuclear medicine were defined. Among them were: cardiac nuclear medicine, neuro-psychiatric nuclear medicine, and cancer diagnosis through direct tumor imaging. A powerful new tool, Positron Emission Tomography (PET) was lauded as the impetus for new developments in nuclear medicine. The political environment (funding, degree of autonomy) was discussed, as were the economic and scientific environments

  14. Research on the status of acceptance of Fukushima nuclear power accidents and the understanding of knowledge for college students

    International Nuclear Information System (INIS)

    Wang Yilong; Liao Li; He Xu

    2012-01-01

    Objective To investigate the connection between the understanding of basic knowledge of nuclear power and whether to accept the changes in attitude with Fukushima nuclear accidents for college students who were education in public. Methods 3000 questionnaires were distributed for college students by anonymity before and after the accident in the Fukushima nuclear power plant, respectively. Results the results of investigation showed that Fukushima nuclear accidents have influenced on the mental of college students, there significant differences between the two investigations. Conclusion college students have a little knowledge of nuclear power, it is necessary to strengthen publicity and education efforts for college students. (authors)

  15. Nuclear medicine and neurology

    International Nuclear Information System (INIS)

    Paris, M.; Samarina, G.; Kelk, E.; Poksi, A.; Nazarenko, S.

    2005-01-01

    Methods of nuclear medicine are based on the use of radioactive isotopes bound to specific marker substances. Administered radioactive markers enter metabolic processes. SPET and PET cameras enable, with their detectors, to register gamma quanta resulting from isotope decay, transform the absorbed quanta into visible light and process the registered signals by means of a computer system. Thus the functions of a living organism can be observed at the molecular level. Special markers capable of crossing the haematin-cephalic barrier and targeting neural metabolic processes are used for visualization of brain perfusion and neurotransmission at SPET and PET, serving for defection of diseases. These procedures are of special significance for the diagnosis of neurodegenerative diseases where the diagnostic value of anatomical-structural methods like CT and conventional MRI is low and where timely administration of proper neuroprotecfive measures contributes to improved disease management. SPET studies of brain perfusion enable to make early diagnosis of Alzheimer's disease due to typical perfusion defects which appear at the preclinical stage and allow to distinguish this disease from other dementia syndromes. Parkinson's disease has a latent period of 3-4 years before the clinical signs appear. SPET with dopamine receptors visualizes striatal dopaminergic presynaptic hypofunction providing the diagnosis at the early stage. Procedures of nuclear medicine enable to establish the differential diagnosis of various Parkinsonian syndromes. SPET and PET research helps to understand better pathophysiological processes, pharmacokinetics and pharmacodynamics in living organisms.(authors) [et

  16. Nuclear links

    International Nuclear Information System (INIS)

    1981-01-01

    The subject is dealt with in sections: introduction; energy and the third world; world energy consumption 1978; oil -the energy dilemma; nuclear chains - introduction; uranium; Namibia; enrichment and reprocessing; countries with enrichment and reprocessing facilities; waste; conclusion; why take the nuclear option; third world countries with nuclear reactors; the arms connection; government spending and human resources 1977 (by countries); nuclear power - the final solution; the fascists; world bank; campaigns; community action in Plogoff; Australian labour movement; NUM against nuclear power; Scottish campaign; students against nuclear energy; anti-nuclear campaign; partizans; 3W1 disarmament and development; campaign ATOM; CANUC; 3W1; SANE. (U.K.)

  17. Nuclear terrorism

    OpenAIRE

    RUTIC SRDJAN Z.

    2016-01-01

    The paper has analyzed different manifestations of terrorism with nuclear weapons and ionizing radiation as a special kind of terrorism. Possibilities that terrorist groups come into possession of nuclear weapons and apply them for terrorist purposes have been analysed. The forms and methods of terrorist activities with nuclear means have been given as well. It has been concluded that nuclear terrorism includes various forms of threats, including not only nuclear weapons but also the sources ...

  18. Does anonymous sperm donation increase the risk for unions between relatives and the incidence of autosomal recessive diseases due to consanguinity?

    Science.gov (United States)

    Serre, Jean-Louis; Leutenegger, Anne-Louise; Bernheim, Alain; Fellous, Marc; Rouen, Alexandre; Siffroi, Jean-Pierre

    2014-03-01

    In France gamete donation and notably sperm donation are anonymous. It has been claimed that anonymous artificial insemination by donor (AID) could highly contribute to an increase in the level of consanguinity and the incidence of autosomal recessive diseases, due to the unions between offspring of anonymous donors, unaware of their biological kinship, with the special case of unions between half-siblings. The actual incidence of consanguinity due to AID was compared with that resulting from the two other main sources of consanguinity and recessive diseases, i.e. voluntary unions between related individuals or inadvertent unions between the offspring of a common unknown male ancestor (false paternity). From these data, we estimated that expected unions in France between half sibs per year are 0.12 between offspring of sperm donors (1.2 every 10 years) and 0.5 between offspring of common male ancestors through false paternity (5 every 10 years). More generally, the inadvertent unions between false paternity offspring are roughly four times more frequent than those resulting from anonymous AID. We estimated that in the future, when AID has been in practice for several generations, out the 820 000 annual births in France, respectively, 6 and 25 births will be consanguineous through an unknown common ancestor related to anonymous AID and to a false paternity, both of which are negligible when compared with the 1256 children born from first-degree cousins. About 672 children per year are born with a recessive genetic disease due to the panmictic risk and additional affected cases due to consanguinity would be 34.54 for first-cousin offspring, 0.33 for offspring of individuals related due to false paternity and 0.079 for offspring of individuals related due to anonymous AID. Anonymous AID would therefore be responsible for 0.46% of consanguineous births and for 0.01% of recessive diseases. Therefore, the effect of anonymous AID on half-sibling unions, consanguinity and

  19. The Ring of Gyges: Anonymity and Technological Advance’s Effect on the Deterrence of Non-State Actors in 2035

    Science.gov (United States)

    2011-02-16

    NOTE AIR WAR COLLEGE AIR UNIVERSITY THE RING OF GYGES: ANONYMITY AND TECHNOLOGICAL ADVANCE‘S EFFECT ON THE DETERRENCE OF NON-STATE ACTORS IN...00-00-2011 4. TITLE AND SUBTITLE The Ring of Gyges: Anonymity and Technological Advance’s Effect on the Deterrence of Non-State Actors in 2035 5a...CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING

  20. Nuclear safeguards and nuclear shutdowns

    International Nuclear Information System (INIS)

    Worthington, J.D.

    1976-01-01

    The issues involved in the California nuclear initiative (Proposition 15) are described. Some of the characteristics of the anti-nuclear lobby are outlined. Some do's and don'ts for the nuclear group are listed. The nuclear shutdown effort was concentrated on the safeguards and high-level waste disposal issues

  1. Markers of hepatic fibrosis.

    Science.gov (United States)

    Caballería, Llorenç; Torán, Pere; Caballería, Joan

    2017-10-18

    Chronic liver diseases constitute a major health problem. Chronic liver inflammation, defined by the degree of hepatic fibrosis, is asymptomatic in a significant percentage of patients; hence, the disease often remains undiagnosed until it has reached very advanced phases and, frequently, when the damage is irreversible. Ideally, patients should be screened during the initial phases of chronic inflammation, thus allowing for the effective management of the natural evolution of the disease by stopping or delaying its course. Standard diagnostic methods (transaminase determination or abdominal ultrasonography) do not allow for the early diagnosis of the degree of fibrosis. A liver biopsy is the invasive method of choice to screen for fibrosis, however, due to its limitations, non-invasive diagnostic methods such as elastography or serological markers are increasingly used as a good alternative for the early diagnosis of the degree of fibrosis. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.

  2. Cancer and tumour markers

    International Nuclear Information System (INIS)

    Osifo, B.

    1999-02-01

    Cancer has been a major cause of death world wide and in Nigeria there are six commonest forms of manifestation of cancer known. Of these prostrate cancer is the highest with 16% occurrence of all known cancers according to a study by the Histopathology Department of the UCH. Many factors, amongst them dietary, environmental, lifestyle, age and sedentary work are possible causes. With the global rise in incidents, the IAEA initiated the Tumour Marker Project as a means of screening cancers in 15 African countries including Nigeria. In Nigeria, 4 groups of the commonest cancers have been chosen for screening. These are prostrate cancer, primary liver cancer, cancer of the GI tract and trophoblastic cancer

  3. Tumor markers in colorectal cancer

    OpenAIRE

    Fernandes, Luís César [UNIFESP; Matos, Delcio [UNIFESP

    2002-01-01

    Colorectal cancer is a clinical entity of a persistent relevance in clinical practice and its early diagnosis is a determinant factor to obtain better therapeutic results. Tumor markers are helpful means for a better approach to individuals with such neoplasm. In the present review, the authors analyze the phases in which surgical-clinical treatment markers must be used: diagnosis, determination of tumor stage, establishment of prognosis and detection of recurrence. Current and future markers...

  4. Molecular marker applications in plants.

    Science.gov (United States)

    Hayward, Alice C; Tollenaere, Reece; Dalton-Morgan, Jessica; Batley, Jacqueline

    2015-01-01

    Individuals within a population of a sexually reproducing species will have some degree of heritable genomic variation caused by mutations, insertion/deletions (INDELS), inversions, duplications, and translocations. Such variation can be detected and screened using molecular, or genetic, markers. By definition, molecular markers are genetic loci that can be easily tracked and quantified in a population and may be associated with a particular gene or trait of interest. This chapter will review the current major applications of molecular markers in plants.

  5. Biochemical markers of bone turnover

    International Nuclear Information System (INIS)

    Kim, Deog Yoon

    1999-01-01

    Biochemical markers of bone turnover has received increasing attention over the past few years, because of the need for sensitivity and specific tool in the clinical investigation of osteoporosis. Bone markers should be unique to bone, reflect changes of bone less, and should be correlated with radiocalcium kinetics, histomorphometry, or changes in bone mass. The markers also should be useful in monitoring treatment efficacy. Although no bone marker has been established to meet all these criteria, currently osteocalcin and pyridinium crosslinks are the most efficient markers to assess the level of bone turnover in the menopausal and senile osteoporosis. Recently, N-terminal telopeptide (NTX), C-terminal telopeptide (CTX) and bone specific alkaline phosphatase are considered as new valid markers of bone turnover. Recent data suggest that CTX and free deoxypyridinoline could predict the subsequent risk of hip fracture of elderly women. Treatment of postmenopausal women with estrogen, calcitonin and bisphosphonates demonstrated rapid decrease of the levels of bone markers that correlated with the long-term increase of bone mass. Factors such as circadian rhythms, diet, age, sex, bone mass and renal function affect the results of biochemical markers and should be appropriately adjusted whenever possible. Each biochemical markers of bone turnover may have its own specific advantages and limitations. Recent advances in research will provide more sensitive and specific assays

  6. Biochemical markers of bone turnover

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Deog Yoon [College of Medicine, Kyunghee Univ., Seoul (Korea, Republic of)

    1999-08-01

    Biochemical markers of bone turnover has received increasing attention over the past few years, because of the need for sensitivity and specific tool in the clinical investigation of osteoporosis. Bone markers should be unique to bone, reflect changes of bone less, and should be correlated with radiocalcium kinetics, histomorphometry, or changes in bone mass. The markers also should be useful in monitoring treatment efficacy. Although no bone marker has been established to meet all these criteria, currently osteocalcin and pyridinium crosslinks are the most efficient markers to assess the level of bone turnover in the menopausal and senile osteoporosis. Recently, N-terminal telopeptide (NTX), C-terminal telopeptide (CTX) and bone specific alkaline phosphatase are considered as new valid markers of bone turnover. Recent data suggest that CTX and free deoxypyridinoline could predict the subsequent risk of hip fracture of elderly women. Treatment of postmenopausal women with estrogen, calcitonin and bisphosphonates demonstrated rapid decrease of the levels of bone markers that correlated with the long-term increase of bone mass. Factors such as circadian rhythms, diet, age, sex, bone mass and renal function affect the results of biochemical markers and should be appropriately adjusted whenever possible. Each biochemical markers of bone turnover may have its own specific advantages and limitations. Recent advances in research will provide more sensitive and specific assays.

  7. Comparative analysis of population genetic structure in Athyrium distentifolium (Pteridophyta) using AFLPs and SSRs from anonymous and transcribed gene regions.

    Science.gov (United States)

    Woodhead, M; Russell, J; Squirrell, J; Hollingsworth, P M; Mackenzie, K; Gibby, M; Powell, W

    2005-05-01

    To examine the performance and information content of different marker systems, comparative assessment of population genetic diversity was undertaken in nine populations of Athyrium distentifolium using nine genomic and 10 expressed sequence tag (EST) microsatellite (SSR) loci, and 265 amplified fragment length polymorphism (AFLP) loci from two primer combinations. In range-wide comparisons (European vs. North American populations), the EST-SSR loci showed more reliable amplification and produced more easily scorable bands than genomic simple sequence repeats (SSRs). Genomic SSRs showed significantly higher levels of allelic diversity than EST-SSRs, but there was a significant correlation in the rank order of population diversities revealed by both marker types. When AFLPs, genomic SSRs, and EST-SSRs are considered, comparisons of different population diversity metrics/markers revealed a mixture of significant and nonsignificant rank-order correlations. However, no hard incongruence was detected (in no pairwise comparison of populations did different marker systems or metrics detect opposingly significant different amounts of variation). Comparable population pairwise estimates of F(ST) were obtained for all marker types, but whilst absolute values for genomic and EST-SSRs were very similar (F(ST) = 0.355 and 0.342, respectively), differentiation was consistently higher for AFLPs in pairwise and global comparisons (global AFLP F(ST) = 0.496). The two AFLP primer combinations outperformed 18 SSR loci in assignment tests and discriminatory power in phenetic cluster analyses. The results from marker comparisons on A. distentifolium are discussed in the context of the few other studies on natural plant populations comparing microsatellite and AFLP variability.

  8. Oral cancer risk and molecular markers.

    Science.gov (United States)

    Chimenos-Küstner, Eduardo; Font-Costa, Imma; López-López, José

    2004-01-01

    The clinical appearance and, especially, the degree of dysplasia that may be shown by pre-cancerous lesions in the oral cavity suggest a potential for malignisation. An increasing number of studies are seeking new, more specific markers that would help to determine the degree of cell alteration and enable a better understanding of the degree of malignant degeneration of these cells. The present review considers the most recent findings for these markers, grouping them into families: tumour growth markers; markers of tumour suppression and anti-tumour response; angiogenesis markers; markers of tumour invasion and metastatic potential; cell surface markers; intracellular markers; markers derived from arachidonic acid; and enzymatic markers.

  9. Simple parametric survival analysis with anonymized register data: A cohort study with truncated and interval censored event and censoring times

    Directory of Open Access Journals (Sweden)

    Kristiansen Ivar S

    2011-08-01

    Full Text Available Abstract Background To preserve patient anonymity, health register data may be provided as binned data only. Here we consider as example, how to estimate mean survival time after a diagnosis of metastatic colorectal cancer from Norwegian register data on time to death or censoring binned into 30 day intervals. All events occurring in the first three months (90 days after diagnosis were removed to achieve comparability with a clinical trial. The aim of the paper is to develop and implement a simple, and yet flexible method for analyzing such interval censored and truncated data. Methods Considering interval censoring a missing data problem, we implement a simple multiple imputation strategy that allows flexible sensitivity analyses with respect to the shape of the censoring distribution. To allow identification of appropriate parametric models, a χ2-goodness-of-fit test--also imputation based--is derived and supplemented with diagnostic plots. Uncertainty estimates for mean survival times are obtained via a simulation strategy. The validity and statistical efficiency of the proposed method for varying interval lengths is investigated in a simulation study and compared with simpler alternatives. Results Mean survival times estimated from the register data ranged from 1.2 (SE = 0.09 to 3.2 (0.31 years depending on period of diagnosis and choice of parametric model. The shape of the censoring distribution within intervals did generally not influence results, whereas the choice of parametric model did, even when different models fit the data equally well. In simulation studies both simple midpoint imputation and multiple imputation yielded nearly unbiased analyses (relative biases of -0.6% to 9.4% and confidence intervals with near-nominal coverage probabilities (93.4% to 95.7% for censoring intervals shorter than six months. For 12 month censoring intervals, multiple imputation provided better protection against bias, and coverage probabilities

  10. Iconoclasts Anonymous: Why did it take Historians so long to identify the Image-breakers of 1566?

    Directory of Open Access Journals (Sweden)

    Judith Pollmann

    2016-03-01

    Full Text Available This article asks why until the mid-twentieth century both Catholic and Protestant interpretations of the iconoclasm converged on the anonymising of the iconoclasts of 1566. It argues that, while a greater availability of sources, better source criticism and international debates helped eventually to give the iconoclasts a face, the main reason why it has took so long for the image-breakers to lose their anonymity was that it was in no one’s interest to identify the culprits. For centuries, Protestants considered the iconoclasm an embarrassment, and preferred to dismiss its perpetrators as ‘rabble’, while Catholics in the Southern Netherlands tended to dismiss them as foreigers, manipulated by the nobility. Their anonymity was lifted through the intervention of German historian Erich Kuttner, whose main thesis was proven wrong, but at last triggered serious research into the identity of the iconoclasts, as well as alternative explanations of their motives. ‘Iconoclasts Anonymous’. Waarom duurde het zo lang voordat historici de beeldenstormers van 1566 identificeerden?Dit artikel werpt de vraag op waarom zowel katholieke als protestantse geschiedschrijvers tot de tweede helft van de twintigste eeuw zo weinig belangstelling hadden voor de identiteit van de beeldenstormers van 1566. Hoewel bredere beschikbaarheid van bronnenmateriaal, betere bronnenkritiek en internationale debatten uiteindelijk hielpen om de beeldenstormers een gezicht te kunnen geven, betoogt dit artikel dat het eeuwenlang vooral in niemands belang was om de daders te identificeren. Protestanten vonden de herinnering aan de Beeldenstorm erg pijnlijk en maakten daarom anoniem arm ‘gespuis’ tot zondebok, terwijl katholieken in de Zuidelijke Nederlanden ze het liefst wegzetten als de buitenlandse werktuigen van opstandige edellieden. Hun anonimiteit werd opgeheven door de interventie van de Duitse historicus Erich Kuttner, wiens interpretatie

  11. Tumor markers in clinical oncology

    International Nuclear Information System (INIS)

    Novakovic, S.

    2004-01-01

    The subtle differences between normal and tumor cells are exploited in the detection and treatment of cancer. These differences are designated as tumor markers and can be either qualitative or quantitative in their nature. That means that both the structures that are produced by tumor cells as well as the structures that are produced in excessive amounts by host tissues under the influence of tumor cells can function as tumor markers. Speaking in general, the tumor markers are the specific molecules appearing in the blood or tissues and the occurrence of which is associated with cancer. According to their application, tumor markers can be roughly divided as markers in clinical oncology and markers in pathology. In this review, only tumor markers in clinical oncology are going to be discussed. Current tumor markers in clinical oncology include (i) oncofetal antigens, (ii) placental proteins, (iii) hormones, (iv) enzymes, (v) tumor-associated antigens, (vi) special serum proteins, (vii) catecholamine metabolites, and (viii) miscellaneous markers. As to the literature, an ideal tumor marker should fulfil certain criteria - when using it as a test for detection of cancer disease: (1) positive results should occur in the early stages of the disease, (2) positive results should occur only in the patients with a specific type of malignancy, (3) positive results should occur in all patients with the same malignancy, (4) the measured values should correlate with the stage of the disease, (5) the measured values should correlate to the response to treatment, (6) the marker should be easy to measure. Most tumor markers available today meet several, but not all criteria. As a consequence of that, some criteria were chosen for the validation and proper selection of the most appropriate marker in a particular malignancy, and these are: (1) markers' sensitivity, (2) specificity, and (3) predictive values. Sensitivity expresses the mean probability of determining an elevated tumor

  12. JPRS Report, Nuclear Developments

    National Research Council Canada - National Science Library

    1989-01-01

    Partial Contents: Nuclear Weapons, Nuclear Development, Nuclear Power Plant, Uranium, Missiles, Space Firm Protested, Satellite, Rocket Launching, Nuclear Submarine, Environmental, Radioactivity, Nuclear Plant...

  13. Marker Detection in Aerial Images

    KAUST Repository

    Alharbi, Yazeed

    2017-04-09

    The problem that the thesis is trying to solve is the detection of small markers in high-resolution aerial images. Given a high-resolution image, the goal is to return the pixel coordinates corresponding to the center of the marker in the image. The marker has the shape of two triangles sharing a vertex in the middle, and it occupies no more than 0.01% of the image size. An improvement on the Histogram of Oriented Gradients (HOG) is proposed, eliminating the majority of baseline HOG false positives for marker detection. The improvement is guided by the observation that standard HOG description struggles to separate markers from negatives patches containing an X shape. The proposed method alters intensities with the aim of altering gradients. The intensity-dependent gradient alteration leads to more separation between filled and unfilled shapes. The improvement is used in a two-stage algorithm to achieve high recall and high precision in detection of markers in aerial images. In the first stage, two classifiers are used: one to quickly eliminate most of the uninteresting parts of the image, and one to carefully select the marker among the remaining interesting regions. Interesting regions are selected by scanning the image with a fast classifier trained on the HOG features of markers in all rotations and scales. The next classifier is more precise and uses our method to eliminate the majority of the false positives of standard HOG. In the second stage, detected markers are tracked forward and backward in time. Tracking is needed to detect extremely blurred or distorted markers that are missed by the previous stage. The algorithm achieves 94% recall with minimal user guidance. An average of 30 guesses are given per image; the user verifies for each whether it is a marker or not. The brute force approach would return 100,000 guesses per image.

  14. Nuclear forensics

    International Nuclear Information System (INIS)

    Venugopal, V.

    2010-01-01

    Nuclear forensics is the analysis of nuclear materials recovered from either the capture of unused materials, or from the radioactive debris following a nuclear explosion and can contribute significantly to the identification of the sources of the materials and the industrial processes used to obtain them. In the case of an explosion, nuclear forensics can also reconstruct key features of the nuclear device. Nuclear forensic analysis works best in conjunction with other law enforcement, radiological protection dosimetry, traditional forensics, and intelligence work to provide the basis for attributing the materials and/or nuclear device to its originators. Nuclear forensics is a piece of the overall attribution process, not a stand-alone activity

  15. Nuclear Scans

    Science.gov (United States)

    Nuclear scans use radioactive substances to see structures and functions inside your body. They use a special ... images. Most scans take 20 to 45 minutes. Nuclear scans can help doctors diagnose many conditions, including ...

  16. Quem controla a política de ninguém? Anonymous Brasil e o ativismo hacker nas redes de comunicação (Who control the politics of no one? Anonymous Brazil and hacktivism in communication networks Doi: 10.5212/Emancipacao.v.15i2.0008

    Directory of Open Access Journals (Sweden)

    Bárbara Maria Farias Mota

    2016-08-01

    Full Text Available Resumo: Esse artigo analisa a atuação política dos hackers a partir de um estudo de caso da rede Anonymous Brasil, uma das vertentes do hacktivismo no contexto brasileiro. Para tanto, utiliza as postagens de um dos diferentes perfis Anonymous no Twitter, no período da Operação Hacking Cup (#OpHackingCup, que consistiu em uma série de protestos virtuais contra a Copa do Mundo de 2014. Metodologicamente, o desenho de pesquisa adota uma abordagem multimétodo, unindo análise de conteúdo e estatística descritiva. Os resultados evidenciam que por meio da utilização de ferramentas digitais transgressivas e do anonimato, esses atores não estatais evidenciam táticas estratégicas de ação diante do controle/vigilância presentes na sociedade contemporânea. Palavras-chave: Anonymous Brasil. Ativismo hacker. Redes informacionais. Abstract: This article analyses the political actuation of hackers from a study case of the Anonymous Brazil network, one of the faces of hacktivism in the Brazilian context. For such, this paper utilises tweets from one Anonymous profile in Twitter, during the period of the Operation Hacking Cup (#OpHackingCup, which entailed several digital protests against the 2014 World Cup. Methodologically, this paper adopts a research design based on a multi-method approach, uniting content analysis and descriptive statistics. The results show that, by the means of transgressive digital tools and anonymity, those actors spotlight strategical tactics as a countermeasure to the control/surveillance that is present in the contemporary society. Keywords: Anonymous Brazil. Hacktivism. Informational networks.

  17. Early localization of NPA58, a rat nuclear pore-associated protein

    Indian Academy of Sciences (India)

    We have studied the mitotic reassembly of the nuclear envelope, using antibodies to nuclear marker proteins and NPA58 in F-111 rat fibroblast cells. In earlier studies we have proposed that NPA58, a 58 kDa rat nuclear protein, is involved in nuclear protein import. In this report, NPA58 is shown to be localized on the ...

  18. Nuclear structure

    International Nuclear Information System (INIS)

    Eastham, D.A.; Joy, T.

    1986-01-01

    The paper on 'nuclear structure' is the Appendix to the Daresbury (United Kingdom) Annual Report 1985/86, and contains the research work carried out at the Nuclear Structure Facility, Daresbury, within that period. During the year a total of 74 experiments were scheduled covering the main areas of activity including: nuclear collective motion, nuclei far from stability, and nuclear collisions. The Appendix contains brief reports on these experiments and associated theory. (U.K.)

  19. Testing theories about ethnic markers

    DEFF Research Database (Denmark)

    Jensen, Niels Holm; Petersen, Michael Bang; Høgh-Olesen, Henrik

    2015-01-01

    In recent years, evolutionary psychologists and anthropologists have debated whether ethnic markers have evolved to solve adaptive problems related to interpersonal coordination or to interpersonal cooperation. In the present study, we add to this debate by exploring how individuals living...... speakers. Taken together, the results suggest that humans utilize ethnic markers of unfamiliar individuals to coordinate behavior rather than to cooperate....

  20. Nuclear electronics

    International Nuclear Information System (INIS)

    Friese, T.

    1981-09-01

    A short survey is given on nuclear radiation detectors and nuclear electronics. It is written for newcomers and those, who are not very familiar with this technique. Some additional information is given on typical failures in nuclear measurement systems. (orig.) [de