WorldWideScience

Sample records for anomalous skin effect

  1. Influence of External Magnetic Field on Anomalous Skin Effects in Inductively Coupled Plasmas

    Institute of Scientific and Technical Information of China (English)

    MAO Ming; WANG You-Nian

    2004-01-01

    @@ Using a one-dimensional slab model, we study the influence of the external static magnetic field on the anomalous skin effects in the inductively coupled plasma. The rf electromagnetic field in the plasma is determined by solving the linearized Boltzmann equation incorporating with the Maxwell equations. The numerical results show that,due to the existence of the external magnetic field, the anomalous skin effects are greatly enhanced and the number of regions with negative absorption is decreased.

  2. Surface impedance in the anomalous skin effect regime

    Science.gov (United States)

    Chrzanowski, Janusz; Kirkiewicz, Józef

    2008-12-01

    An analytical solution of the surface impedance is obtained using the kinetic equation with the collision integral that takes into account the Fermi liquid effects. It is assumed that the reflection of electrons is purely diffusive. Particular attention is paid to the influence of external magnetic field and polarization of the incident wave on the real and imagine part of the surface impedance.

  3. Predicting molecular scale skin-effect in electrochemical impedance due to anomalous subdiffusion mediated adsorption phenomenon

    Science.gov (United States)

    Kushagra, Arindam

    2016-02-01

    Anomalous subdiffusion governs the processes which are not energetically driven, on a molecular scale. This paper proposes a model to predict the response of electrochemical impedance due to such diffusion process. Previous works considered the use of fractional calculus to predict the impedance behaviour in response to the anomalous diffusion. Here, we have developed an expression which predicts the skin-effect, marked by an increase in the impedance with increasing frequency, in this regime. Negative inductances have also been predicted as a consequence of the inertial response of adsorbed species upon application of frequency-mediated perturbations. It might help the researchers in the fields of impedimetric sensors to choose the working frequency and those working in the field of batteries to choose the parameters, likewise. This work would shed some light into the molecular mechanisms governing the impedance when exposed to frequency-based perturbations like electromagnetic waves (microwaves to ionizing radiations) and in charge storage devices like batteries etc.

  4. Predicting molecular scale skin-effect in electrochemical impedance due to anomalous subdiffusion mediated adsorption phenomenon

    Directory of Open Access Journals (Sweden)

    Arindam Kushagra

    2016-02-01

    Full Text Available Anomalous subdiffusion governs the processes which are not energetically driven, on a molecular scale. This paper proposes a model to predict the response of electrochemical impedance due to such diffusion process. Previous works considered the use of fractional calculus to predict the impedance behaviour in response to the anomalous diffusion. Here, we have developed an expression which predicts the skin-effect, marked by an increase in the impedance with increasing frequency, in this regime. Negative inductances have also been predicted as a consequence of the inertial response of adsorbed species upon application of frequency-mediated perturbations. It might help the researchers in the fields of impedimetric sensors to choose the working frequency and those working in the field of batteries to choose the parameters, likewise. This work would shed some light into the molecular mechanisms governing the impedance when exposed to frequency-based perturbations like electromagnetic waves (microwaves to ionizing radiations and in charge storage devices like batteries etc.

  5. Optical properties of metals: Infrared emissivity in the anomalous skin effect spectral region

    Energy Technology Data Exchange (ETDEWEB)

    Echániz, T. [Departamento de Física de la Materia Condensada, Facultad de Ciencia y Tecnología, UPV/EHU, Sarriena s/n, Leioa 48940 (Spain); Pérez-Sáez, R. B., E-mail: raul.perez@ehu.es; Tello, M. J. [Departamento de Física de la Materia Condensada, Facultad de Ciencia y Tecnología, UPV/EHU, Sarriena s/n, Leioa 48940 (Spain); Instituto de Síntesis y Estudio de Materiales, Universidad del País Vasco, Apdo. 644, Bilbao 48080 (Spain)

    2014-09-07

    When the penetration depth of an electromagnetic wave in a metal is similar to the mean free path of the conduction electrons, the Drude classical theory is no longer satisfied and the skin effect becomes anomalous. Physical parameters of this theory for twelve metals were calculated and analyzed. The theory predicts an emissivity peak ε{sub peak} at room temperature in the mid-infrared for smooth surface metals that moves towards larger wavelengths as temperature decreases. Furthermore, the theory states that ε{sub peak} increases with the emission angle but its position, λ{sub peak}, is constant. Copper directional emissivity measurements as well as emissivity obtained using optical constants data confirm the predictions of the theory. Considering the relationship between the specularity parameter p and the sample roughness, it is concluded that p is not the simple parameter it is usually assumed to be. Quantitative comparison between experimental data and theoretical predictions shows that the specularity parameter can be equal to one for roughness values larger than those predicted. An exhaustive analysis of the experimental optical parameters shows signs of a reflectance broad peak in Cu, Al, Au, and Mo around the wavelength predicted by the theory for p = 1.

  6. Optical properties of metals: Infrared emissivity in the anomalous skin effect spectral region

    International Nuclear Information System (INIS)

    When the penetration depth of an electromagnetic wave in a metal is similar to the mean free path of the conduction electrons, the Drude classical theory is no longer satisfied and the skin effect becomes anomalous. Physical parameters of this theory for twelve metals were calculated and analyzed. The theory predicts an emissivity peak εpeak at room temperature in the mid-infrared for smooth surface metals that moves towards larger wavelengths as temperature decreases. Furthermore, the theory states that εpeak increases with the emission angle but its position, λpeak, is constant. Copper directional emissivity measurements as well as emissivity obtained using optical constants data confirm the predictions of the theory. Considering the relationship between the specularity parameter p and the sample roughness, it is concluded that p is not the simple parameter it is usually assumed to be. Quantitative comparison between experimental data and theoretical predictions shows that the specularity parameter can be equal to one for roughness values larger than those predicted. An exhaustive analysis of the experimental optical parameters shows signs of a reflectance broad peak in Cu, Al, Au, and Mo around the wavelength predicted by the theory for p = 1

  7. Characteristics of anomalous skin effect and evolution of power absorption regions in a cylindrical radio frequency inductively coupled plasma

    International Nuclear Information System (INIS)

    In a low-pressure radio-frequency (13.56 MHz), inductively coupled argon plasma generated by a normal cylindrical rf coil, electric field, current density, and absorbed power density is calculated from magnetic field measured with a phase-resolved magnetic probe. The anomalous skin effect (ASE) for the cylindrical rf coil is compared to those previously reported for the planar and re-entrant cylindrical rf coils. Physical reasons for our observed characteristics of ASE are presented. With the increasing discharge power, the size and the number of negative and positive power absorption regions evolve into several distinct patterns. For the low discharge power (at 156.9 W), there is one area of positive and one area of negative power absorption in the radial direction. For the medium discharge power (279 W–683.5 W), there are two areas of negative and two areas of positive power absorption. For the even higher discharge power (above 803.5 W), the number of areas is the same as that of the medium discharge power, but the size of the inner positive and negative power absorption areas is approximately doubled and halved, respectively, while the outer positive and negative power absorption areas slightly shrinks. The evolution of positive and negative power absorption regions is explained as a result of electron thermal diffusion and the energy conversion between rf current and electric field. The spatial decays of electric field and current density are also elucidated by linking them with the positive and negative power absorption pattern

  8. Characteristics of anomalous skin effect and evolution of power absorption regions in a cylindrical radio frequency inductively coupled plasma

    Energy Technology Data Exchange (ETDEWEB)

    Ding, Z. F., E-mail: zfding@dlut.edu.cn [Key Laboratory of Materials Modification by Laser, Ion, and Electron Beams, Ministry of Education, School of Physics and Optoelectronic Technology, Dalian University of Technology, Dalian 116023 (China); Sun, B. [Key Laboratory of Materials Modification by Laser, Ion, and Electron Beams, Ministry of Education, School of Physics and Optoelectronic Technology, Dalian University of Technology, Dalian 116023 (China); Xi' an Aerospace Propulsion Institute, China Aerospace Science and Technology Corporation, Xi' an 710100 (China); Huo, W. G. [Key Laboratory of Materials Modification by Laser, Ion, and Electron Beams, Ministry of Education, School of Physics and Optoelectronic Technology, Dalian University of Technology, Dalian 116023 (China); School of Physics and Electronic Technology, Liaoning Normal University, Dalian 116029 (China)

    2015-06-15

    In a low-pressure radio-frequency (13.56 MHz), inductively coupled argon plasma generated by a normal cylindrical rf coil, electric field, current density, and absorbed power density is calculated from magnetic field measured with a phase-resolved magnetic probe. The anomalous skin effect (ASE) for the cylindrical rf coil is compared to those previously reported for the planar and re-entrant cylindrical rf coils. Physical reasons for our observed characteristics of ASE are presented. With the increasing discharge power, the size and the number of negative and positive power absorption regions evolve into several distinct patterns. For the low discharge power (at 156.9 W), there is one area of positive and one area of negative power absorption in the radial direction. For the medium discharge power (279 W–683.5 W), there are two areas of negative and two areas of positive power absorption. For the even higher discharge power (above 803.5 W), the number of areas is the same as that of the medium discharge power, but the size of the inner positive and negative power absorption areas is approximately doubled and halved, respectively, while the outer positive and negative power absorption areas slightly shrinks. The evolution of positive and negative power absorption regions is explained as a result of electron thermal diffusion and the energy conversion between rf current and electric field. The spatial decays of electric field and current density are also elucidated by linking them with the positive and negative power absorption pattern.

  9. Nonlocal Anomalous Hall Effect.

    Science.gov (United States)

    Zhang, Steven S-L; Vignale, Giovanni

    2016-04-01

    The anomalous Hall (AH) effect is deemed to be a unique transport property of ferromagnetic metals, caused by the concerted action of spin polarization and spin-orbit coupling. Nevertheless, recent experiments have shown that the effect also occurs in a nonmagnetic metal (Pt) in contact with a magnetic insulator [yttrium iron garnet (YIG)], even when precautions are taken to ensure that there is no induced magnetization in the metal. We propose a theory of this effect based on the combined action of spin-dependent scattering from the magnetic interface and the spin-Hall effect in the bulk of the metal. At variance with previous theories, we predict the effect to be of first order in the spin-orbit coupling, just as the conventional anomalous Hall effect-the only difference being the spatial separation of the spin-orbit interaction and the magnetization. For this reason we name this effect the nonlocal anomalous Hall effect and predict that its sign will be determined by the sign of the spin-Hall angle in the metal. The AH conductivity that we calculate from our theory is in order of magnitude agreement with the measured values in Pt/YIG structures.

  10. Nonlocal Anomalous Hall Effect

    Science.gov (United States)

    Zhang, Steven S.-L.; Vignale, Giovanni

    2016-04-01

    The anomalous Hall (AH) effect is deemed to be a unique transport property of ferromagnetic metals, caused by the concerted action of spin polarization and spin-orbit coupling. Nevertheless, recent experiments have shown that the effect also occurs in a nonmagnetic metal (Pt) in contact with a magnetic insulator [yttrium iron garnet (YIG)], even when precautions are taken to ensure that there is no induced magnetization in the metal. We propose a theory of this effect based on the combined action of spin-dependent scattering from the magnetic interface and the spin-Hall effect in the bulk of the metal. At variance with previous theories, we predict the effect to be of first order in the spin-orbit coupling, just as the conventional anomalous Hall effect—the only difference being the spatial separation of the spin-orbit interaction and the magnetization. For this reason we name this effect the nonlocal anomalous Hall effect and predict that its sign will be determined by the sign of the spin-Hall angle in the metal. The AH conductivity that we calculate from our theory is in order of magnitude agreement with the measured values in Pt /YIG structures.

  11. The quantum anomalous Hall effect

    OpenAIRE

    LIU, CHAO-XING; Zhang, Shou-Cheng; Qi, Xiao-Liang

    2015-01-01

    The quantum anomalous Hall effect is defined as a quantized Hall effect realized in a system without external magnetic field. Quantum anomalous Hall effect is a novel manifestation of topological structure in many-electron systems, and may have potential applications in future electronic devices. In recent years, quantum anomalous Hall effect has been proposed theoretically and realized experimentally. In this review article, we provide a systematic overview of the theoretical and experimenta...

  12. Anomalous Hall effect in localization regime

    Science.gov (United States)

    Wu, Lin; Zhu, Kai; Yue, Di; Tian, Yuan; Jin, Xiaofeng

    2016-06-01

    The anomalous Hall effect in the ultrathin film regime is investigated in Fe(001)(1-3 nm) films epitaxial on MgO(001). The logarithmic localization correction to longitudinal resistivity and anomalous Hall resistivity are observed at low temperature. We identify that the coefficient of skew scattering has a reduction from metallic to localized regime, while the contribution of side jump has inconspicuous change except for a small drop below 10 K. Furthermore, we discover that the intrinsic anomalous Hall conductivity decreases with the reduction of thickness below 2 nm. Our results provide unambiguous experimental evidence to clarify the problem of localization correction to the anomalous Hall effect.

  13. Anomalous Hall effect in polycrystalline Ni films

    KAUST Repository

    Guo, Zaibing

    2012-02-01

    We systematically studied the anomalous Hall effect in a series of polycrystalline Ni films with thickness ranging from 4 to 200 nm. It is found that both the longitudinal and anomalous Hall resistivity increased greatly as film thickness decreased. This enhancement should be related to the surface scattering. In the ultrathin films (46 nm thick), weak localization corrections to anomalous Hall conductivity were studied. The granular model, taking into account the dominated intergranular tunneling, has been employed to explain this phenomenon, which can explain the weak dependence of anomalous Hall resistivity on longitudinal resistivity as well. © 2011 Elsevier Ltd. All rights reserved.

  14. Anomalous Hall effect for semiclassical chiral fermions

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Pengming, E-mail: zhpm@impcas.ac.cn [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou (China); Horváthy, P.A., E-mail: horvathy@lmpt.univ-tours.fr [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou (China); Laboratoire de Mathématiques et de Physique Théorique, Université de Tours (France)

    2015-03-06

    Semiclassical chiral fermions manifest the anomalous spin-Hall effect: when put into a pure electric field they suffer a side jump, analogous to what happens to their massive counterparts in non-commutative mechanics. The transverse shift is consistent with the conservation of the angular momentum. In a pure magnetic field, instead, spiraling motion is found. Motion in Hall-type perpendicular electric and magnetic fields is also studied. - Highlights: • Chiral fermions exhibit an anomalous spin-Hall effect. • Transverse shift appears in a pure electric field. • In a pure magnetic field spiraling motion is found.

  15. Anomalous Hall Effect for chiral fermions

    CERN Document Server

    Zhang, P -M

    2014-01-01

    Semiclassical chiral fermions manifest the anomalous spin-Hall effect: when put into a pure electric field, they suffer a side jump, analogous to what happens to their massive counterparts in non-commutative mechanics. The transverse shift is consistent with the conservation of the angular momentum. In a pure magnetic field a cork-screw-like, spiraling motion is found.

  16. Anomalous Hall effect in Weyl superconductors

    Science.gov (United States)

    Bednik, G.; Zyuzin, A. A.; Burkov, A. A.

    2016-08-01

    We present a theory of the anomalous Hall effect in a topological Weyl superconductor with broken time reversal symmetry. Specifically, we consider a ferromagnetic Weyl metal with two Weyl nodes of opposite chirality near the Fermi energy. In the presence of inversion symmetry, such a metal experiences a weak-coupling Bardeen–Cooper–Schrieffer instability, with pairing of parity-related eigenstates. Due to the nonzero topological charge, carried by the Weyl nodes, such a superconductor is necessarily topologically nontrivial, with Majorana surface states coexisting with the Fermi arcs of the normal Weyl metal. We demonstrate that, surprisingly, the anomalous Hall conductivity of such a superconducting Weyl metal coincides with that of a nonsuperconducting one, under certain conditions, in spite of the nonconservation of charge in a superconductor. We relate this to the existence of an extra (nearly) conserved quantity in a Weyl metal, the chiral charge.

  17. Anomalous Hall Effect in a Kagome Ferromagnet

    Science.gov (United States)

    Ye, Linda; Wicker, Christina; Suzuki, Takehito; Checkelsky, Joseph; Joseph Checkelsky Team

    The ferromagnetic kagome lattice is theoretically known to possess topological band structures. We have synthesized large single crystals of a kagome ferromagnet Fe3Sn2 which orders ferromagnetically well above room temperature. We have studied the electrical and magnetic properties of these crystals over a broad temperature and magnetic field range. Both the scaling relation of anomalous Hall effect and anisotropic magnetic susceptibility show that the ferromagnetism of Fe3Sn2 is unconventional. We discuss these results in the context of magnetism in kagome systems and relevance to the predicted topological properties in this class of compounds. This research is supported by DMR-1231319.

  18. Quantum anomalous Hall effect with higher plateaus.

    Science.gov (United States)

    Wang, Jing; Lian, Biao; Zhang, Haijun; Xu, Yong; Zhang, Shou-Cheng

    2013-09-27

    The quantum anomalous Hall (QAH) effect in magnetic topological insulators is driven by the combination of spontaneous magnetic moments and spin-orbit coupling. Its recent experimental discovery raises the question if higher plateaus can also be realized. Here, we present a general theory for a QAH effect with higher Chern numbers and show by first-principles calculations that a thin film magnetic topological insulator of Cr-doped Bi2(Se,Te)3 is a candidate for the C=2 QAH insulator. Remarkably, whereas a higher magnetic field leads to lower Hall conductance plateaus in the integer quantum Hall effect, a higher magnetic moment leads to higher Hall conductance plateaus in the QAH effect.

  19. Anomalous Josephson Hall effect in magnet/triplet superconductor junctions

    OpenAIRE

    Yokoyama, Takehito

    2015-01-01

    We investigate anomalous Hall effect in a magnet coupled to a triplet superconductor under phase gradient. It is found that the anomalous Hall supercurrent arises from non-trivial structure of the magnetization. The magnetic structure manifested in the Hall supercurrent is characterized by even order terms of the exchange coupling, essentially different from that discussed in the context of anomalous Hall effect, reflecting the disspationless nature of supercurrent. We also discuss a possible...

  20. Localization corrections to the anomalous Hall effect in a ferromagnet

    OpenAIRE

    Dugaev, V. K.; Crepieux, A.; Bruno, P

    2001-01-01

    We calculate the localization corrections to the anomalous Hall conductivity related to the contribution of spin-orbit scattering into the current vertex (side-jump mechanism). We show that in contrast to the ordinary Hall effect, there exists a nonvanishing localization correction to the anomalous Hall resistivity. The correction to the anomalous Hall conductivity vanishes in the case of side-jump mechanism, but is nonzero for the skew scattering. The total correction to the nondiagonal cond...

  1. Anomalous anisotropic magnetoresistance effects in graphene

    Directory of Open Access Journals (Sweden)

    Yiwei Liu

    2014-09-01

    Full Text Available We investigate the effect of external stimulus (temperature, magnetic field, and gases adsorptions on anisotropic magnetoresistance (AMR in multilayer graphene. The graphene sample shows superlinear magnetoresistance when magnetic field is perpendicular to the plane of graphene. A non-saturated AMR with a value of −33% is found at 10 K under a magnetic field of 7 T. It is surprisingly to observe that a two-fold symmetric AMR at high temperature is changed into a one-fold one at low temperature for a sample with an irregular shape. The anomalous AMR behaviors may be understood by considering the anisotropic scattering of carriers from two asymmetric edges and the boundaries of V+(V- electrodes which serve as active adsorption sites for gas molecules at low temperature. Our results indicate that AMR in graphene can be optimized by tuning the adsorptions, sample shape and electrode distribution in the future application.

  2. Anomalous Hall Effect in non-commutative mechanics

    OpenAIRE

    Horvathy, P. A.

    2006-01-01

    The anomalous velocity term in the semiclassical model of a Bloch electron deviates the trajectory from the conventional one. When the Berry curvature (alias noncommutative parameter) is a monopole in momentum space as found recently in some ferromagnetic semiconductors while observing the anomalous Hall effect, we get a transverse shift, similar to that in the optical Hall effect.

  3. Anomalous Nernst Effect with Magnetocrystalline Anisotropy (110)

    Science.gov (United States)

    Chesman, Carlos; Costa Neto, Jose; Department of Physics-UFRN Team

    2014-03-01

    When a ferromagnetic material is submitted to a temperature gradient and the magnetic field generates voltage on the edges of the samples, this is called the Anomalous Nernst Effect (ANE). The Heusler alloys that currently exhibit this effect are the most promising for spintronics and spin caloritronics. In this study we perform a theoretical investigation of voltage curves associated to the ANE, when the material displays magnetocrystalline anisotropy for experimental results in two configurations, ANE versus applied magnetic field and planar angle variations of ANE. We analyzed three types of magnetocrystalline anisotropy: cubic anisotropy (100) with C4 symmetry, uniaxial anisotropy with C2 symmetry and cubic anisotropy (110). The aim was to prove that cubic anisotropy (110) is equivalent to anisotropy (100) combined with uniaxial anisotropy. Theoretical fitting of experimental ANE data demonstrates this total equivalence and that a new interpretation with the use of cubic anisotropy (110) may be due to the atomic arrangement of the so-called full-Heusler. Comparative analyses of Co2FeAl and Co2MnGe alloys will be presented. CNPq, CAPES, FAPERN.

  4. Large anomalous Nernst effect in a skyrmion crystal

    Science.gov (United States)

    Mizuta, Yo Pierre; Ishii, Fumiyuki

    2016-06-01

    Thermoelectric properties of a model skyrmion crystal were theoretically investigated, and it was found that its large anomalous Hall conductivity, corresponding to large Chern numbers induced by its peculiar spin structure leads to a large transverse thermoelectric voltage through the anomalous Nernst effect. This implies the possibility of finding good thermoelectric materials among skyrmion systems, and thus motivates our quests for them by means of the first-principles calculations as were employed in this study.

  5. A classical picture of anomalous effects in a Tokamak

    Science.gov (United States)

    Hirano, K.

    1984-01-01

    Atomic collisions between plasma ions and a very small amount of neutral particles remaining in a hot plasma plays a very important role for plasma transports and may be an origin of anomalous effects observed in a Tokamak such as the diffusion coefficient independent of the field strength, a rapid plasma density increase during gas puffing and current penetration with anomalously high speed in the start-up phase. The Ohm's law derived by Cowling is used for the analysis.

  6. Phenomenological Spin Transport Theory Driven by Anomalous Nernst Effect

    Science.gov (United States)

    Taniguchi, Tomohiro

    2016-07-01

    Several experimental efforts such as material investigation and structure improvement have been made recently to find a large anomalous Nernst effect in ferromagnetic metals. Here, we develop a theory of spin transport driven by the anomalous Nernst effect in a diffusive ferromagnetic/nonmagnetic multilayer. Starting from a phenomenological formula of a spin-dependent electric current, the theoretical formulas of electric voltage and spin torque generated by the anomalous Nernst effect are derived. The magnitude of the electric voltage generated from the spin current via the inverse spin Hall effect is on the order of 0.1 µV for currently available experimental parameter values. The temperature gradient necessary to switch the magnetization is quite larger than the typical experimental value. The separation of the contributions of the Seebeck and transverse spin Seebeck effects is also discussed.

  7. Anomalous Hall Effect in a 2D Rashba Ferromagnet.

    Science.gov (United States)

    Ado, I A; Dmitriev, I A; Ostrovsky, P M; Titov, M

    2016-07-22

    Skew scattering on rare impurity configurations is shown to dominate the anomalous Hall effect in a 2D Rashba ferromagnet. The mechanism originates in scattering on rare impurity pairs separated by distances of the order of the Fermi wavelength. The corresponding theoretical description goes beyond the conventional noncrossing approximation. The mechanism provides the only contribution to the anomalous Hall conductivity in the most relevant metallic regime and strongly modifies previously obtained results for lower energies in the leading order with respect to impurity strength. PMID:27494487

  8. Quantum Anomalous Hall Effect in Magnetic Insulator Heterostructure

    OpenAIRE

    Xu, Gang; Jing WANG; FELSER, CLAUDIA; Qi, Xiao-Liang; Zhang, Shou-Cheng

    2014-01-01

    Based on ab initio calculations, we predict that a monolayer of Cr-doped (Bi,Sb)2Te3 and GdI2 heterostructure is a quantum anomalous Hall insulator with a non-trivial band gap up to 38 meV. The principle behind our prediction is that the band inversion between two topologically trivial ferromagnetic insulators can result in a non-zero Chern number, which offers a better way to realize the quantum anomalous Hall state without random magnetic doping. In addition, a simple effective model is pre...

  9. Effects of Anomalous Propagation Conditions on Weather Radar Observations

    OpenAIRE

    Bech, Joan; Magaldi, Adolfo; Codina, Bernat; Lorente, Jeroni

    2012-01-01

    In this chapter our objective is to provide an overview of the effects of anomalous propagation conditions on weather radar observations, based mostly on studies performed by the authors during the last decade, summarizing results from recent publications, presentations, or unpublished material. We believe this chapter may be useful as an introductory text for graduate students, or researchers and practitioners dealing with this topic. Throughout the text a spherical symmetric atmosphere is a...

  10. Anomalous Doppler effects in bulk phononic crystal

    International Nuclear Information System (INIS)

    Doppler effects in simple cubic phononic crystal are studied theoretically and numerically. In addition to observing Doppler shifts from a moving source's frequencies inside the gap, we find that Doppler shifts can be multi-order, anisotropic, and the dominant order of shift depends on the band index that the source's frequency is in.

  11. Anomalous effective lagrangians and vector resonance models

    NARCIS (Netherlands)

    Pallante, E.; Petronzio, R.

    1993-01-01

    Chiral lagrangians including vector resonances have been shown to saturate the finite part of some of the counterterms needed to regularize ordinary one-loop effective lagrangians of pseudoscalar interactions with external currents. The equivalence between different models has been discussed in the

  12. Anomalous Hall Effect in Geometrically Frustrated Magnets

    Directory of Open Access Journals (Sweden)

    D. Boldrin

    2012-01-01

    space mechanism based on spin chirality that was originally applied to the pyrochlore Nd2Mo2O7 appears unsatisfactory. Recently, an orbital description based on the Aharonov-Bohm effect has been proposed and applied to both the ferromagnetic pyrochlores Nd2Mo2O7 and Pr2Ir2O7; the first of which features long-ranged magnetic order while the latter is a chiral spin liquid. Two further examples of geometrically frustrated conducting magnets are presented in this paper—the kagome-like Fe3Sn2 and the triangular PdCrO2. These possess very different electronic structures to the 3-dimensional heavy-metal pyrochlores and provide new opportunities to explore the different origins of the AHE. This paper summarises the experimental findings in these materials in an attempt to unite the conflicting theoretical arguments.

  13. Effects of surface and interface scattering on anomalous Hall effect in Co/Pd multilayers

    KAUST Repository

    Guo, Z. B.

    2012-09-27

    In this paper, we report the results of surface and interface scattering on anomalous Hall effect in Co/Pd multilayers with perpendicular magnetic anisotropy. The surface scattering effect has been extracted from the total anomalous Hall effect. By scaling surface scattering contribution with ρAHs∼ργss, the exponent γ has been found to decrease with the increase of surface scattering resistivity, which could account for the thickness-dependent anomalous Hall effect. Interface diffusion induced by rapid thermal annealing modifies not only the magnetization and longitudinal resistivity but also the anomalous Hall effect; a large exponent γ ∼ 5.7 has been attributed to interface scattering-dominated anomalous Hall effect.

  14. Quantum anomalous Hall effect in magnetic topological insulators

    OpenAIRE

    Jing WANG; Lian, Biao; Zhang, Shou-Cheng

    2014-01-01

    The search for topologically non-trivial states of matter has become an important goal for condensed matter physics. Here, we give a theoretical introduction to the quantum anomalous Hall (QAH) effect based on magnetic topological insulators in two-dimension (2D) and three-dimension (3D). In 2D topological insulators, magnetic order breaks the symmetry between the counter-propagating helical edge states, and as a result, the quantum spin Hall effect can evolve into the QAH effect. In 3D, magn...

  15. Quantized Anomalous Hall Effect in Magnetic Topological Insulators

    Institute of Scientific and Technical Information of China (English)

    YU Rui

    2011-01-01

    The Hall effect, the anomalous Hall effect (AHE) and the spin Hall effect are thndamental transport processes in solids arising from the Lorentz force and the spin-orbit coupling respectively. The AHE, in which a voltage transverse to the electric current appears even in the absence of an external magnetic field, was first detected in ferromagnetic (FM) metals in 1881 and later found to arise from the spin-orbit coupling (SOC) between the current and magnetic moments.

  16. Anomalous Hall Effect in a Feromagnetic Rare-Earth Cobalite

    Science.gov (United States)

    Samoilov, A. V.; Yeh, N. C.; Vasquez, R. P.

    1996-01-01

    Rare-Earth manganites and cobalites with the perovskite structure have been a subject of great recent interest because their electrical resistance changes significantly when a magnetic field is applied...we have studied the Hall effect in thin film La(sub 0.5)Ca(sub 0.5)CoO(sub 3) material and have obtained convincing evidence fo the so called anomalous Hall effect, typical for magnetic metals...Our results suggest that near the ferromagnetic ordering temperature, the dominant electron scattering mechanism is the spin fluctuation.

  17. Quantized Anomalous Hall Effect in Magnetic Topological Insulators

    Institute of Scientific and Technical Information of China (English)

    YU Rui

    2011-01-01

    @@ The Hall effect, the anomalous Hall effect (AHE) and the spin Hall effect are fundamental transport processes in solids arising from the Lorentz force and the spin-orbit coupling respectively.The AHE, in which a voltage transverse to the electric current appears even in the absence of an external magnetic field, was first detected in ferromagnetic (FM) metals in 1881 and later found to arise from the spin-orbit coupling (SOC) between the current and magnetic moments.Recent progress on the mechanism of AHE has established a link between the AHE and the topological nature of the Hall current by adopting the Berry-phase concepts in close analogy to the intrinsic spin Hall effect.Given the experimental discovery of the quantum Hall and the quantum spin Hall effects, it is natural to ask whether the AHE can also be quantized.In a quantized anomalous Hall (QAH) insulator, spontaneous magnetic moments and spin-orbit coupling combine to give rise to a topologically non-trivial electronic structure, leading to the quantized Hall effect without any external magnetic field.

  18. Urbanization effects on natural radiation in anomalous areas

    International Nuclear Information System (INIS)

    The urbanization effects and their possible causes on the environmental gamma radiation levels, in an anomalous area, were studied. The field work was accomplished in Guarapari, located in the seacoast of the Brazilian state of Espirito Santo, which is rich in monazite sands, with thorium and uranium contents. The results show clearly that there was a reduction in the levels of external exposition in the streets and squares of Guarapari. It was ascertained that the reduction was due to the materials used in the urbanization. (L.C.J.A.)

  19. Quantum anomalous Hall effect in topological insulator memory

    Energy Technology Data Exchange (ETDEWEB)

    Jalil, Mansoor B. A., E-mail: elembaj@nus.edu.sg [Department of Electrical and Computer Engineering, National University of Singapore, 4 Engineering Drive 3, Singapore, Singapore 117576 (Singapore); Data Storage Institute, Agency for Science, Technology and Research A*STAR, DSI Building, 5 Engineering Drive 1, Singapore, Singapore 117608 (Singapore); Tan, S. G. [Data Storage Institute, Agency for Science, Technology and Research A*STAR, DSI Building, 5 Engineering Drive 1, Singapore, Singapore 117608 (Singapore); Department of Electrical and Computer Engineering, National University of Singapore, 4 Engineering Drive 3, Singapore, Singapore 117576 (Singapore); Siu, Z. B. [Data Storage Institute, Agency for Science, Technology and Research A*STAR, DSI Building, 5 Engineering Drive 1, Singapore, Singapore 117608 (Singapore); NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore (Singapore)

    2015-05-07

    We theoretically investigate the quantum anomalous Hall effect (QAHE) in a magnetically coupled three-dimensional-topological insulator (3D-TI) system. We apply the generalized spin-orbit coupling Hamiltonian to obtain the Hall conductivity σ{sup xy} of the system. The underlying topology of the QAHE phenomenon is then analyzed to show the quantization of σ{sup xy} and its relation to the Berry phase of the system. Finally, we analyze the feasibility of utilizing σ{sup xy} as a memory read-out in a 3D-TI based memory at finite temperatures, with comparison to known magnetically doped 3D-TIs.

  20. Nonlinear dynamics induced anomalous Hall effect in topological insulators

    Science.gov (United States)

    Wang, Guanglei; Xu, Hongya; Lai, Ying-Cheng

    2016-01-01

    We uncover an alternative mechanism for anomalous Hall effect. In particular, we investigate the magnetisation dynamics of an insulating ferromagnet (FM) deposited on the surface of a three-dimensional topological insulator (TI), subject to an external voltage. The spin-polarised current on the TI surface induces a spin-transfer torque on the magnetisation of the top FM while its dynamics can change the transmission probability of the surface electrons through the exchange coupling and hence the current. We find a host of nonlinear dynamical behaviors including multistability, chaos, and phase synchronisation. Strikingly, a dynamics mediated Hall-like current can arise, which exhibits a nontrivial dependence on the channel conductance. We develop a physical understanding of the mechanism that leads to the anomalous Hall effect. The nonlinear dynamical origin of the effect stipulates that a rich variety of final states exist, implying that the associated Hall current can be controlled to yield desirable behaviors. The phenomenon can find applications in Dirac-material based spintronics.

  1. Anomalous Hall effect in Fe/Au multilayers

    KAUST Repository

    Zhang, Q.

    2016-07-22

    To understand the interfacial scattering effect on the anomalous Hall effect (AHE), we prepared multilayers of (Fe(36/n)nm/Au(12/n)nm)n using an e-beam evaporator. This structure design allowed us to investigate the effect of interfacial scattering on the AHE, while keeping the samples\\' thickness and composition unchanged. We measured the (magneto)transport properties of the samples in a wide temperature range (10–310 K) with magnetic fields up to 50 kOe. We found that the scaling between the anomalous Hall resistivity (ρAHE) and longitudinal resistivity (ρxx) can be roughly described by ρAHE∼ργxx with γ=2.65±0.10 and 1.90 ± 0.04 for samples from n=1 to n=4 and samples from n=4 to n=12, respectively. Our quantitative analysis results showed that the interfacial scattering suppresses the contribution of the intrinsic mechanism and gives rise to a side-jump contribution.

  2. Anomalous photoelectric effect of a polycrystalline topological insulator film.

    Science.gov (United States)

    Zhang, Hongbin; Yao, Jiandong; Shao, Jianmei; Li, Hai; Li, Shuwei; Bao, Dinghua; Wang, Chengxin; Yang, Guowei

    2014-07-29

    A topological insulator represents a new state of quantum matter that possesses an insulating bulk band gap as well as a spin-momentum-locked Dirac cone on the surface that is protected by time-reversal symmetry. Photon-dressed surface states and light-induced surface photocurrents have been observed in topological insulators. Here, we report experimental observations of an anomalous photoelectric effect in thin films of Bi2Te3, a polycrystalline topological insulator. Under illumination with non-polarised light, transport measurements reveal that the resistance of the topological surface states suddenly increases when the polycrystalline film is illuminated. The resistance variation is positively dependent on the light intensity but has no relation to the applied electric field; this finding can be attributed to the gap opening of the surface Dirac cone. This observation of an anomalous photoelectric effect in polycrystalline topological insulators offers exciting opportunities for the creation of photodetectors with an unusually broad spectral range. Moreover, polycrystalline topological insulator films provide an attractive material platform for exploring the nature and practical application of topological insulators.

  3. Non-collinear antiferromagnets and the anomalous Hall effect

    Science.gov (United States)

    Kübler, J.; Felser, C.

    2014-12-01

    The anomalous Hall effect is investigated theoretically by employing density functional calculations for the non-collinear antiferromagnetic order of the hexagonal compounds Mn3Ge and Mn3Sn using various planar triangular magnetic configurations as well as unexpected non-planar configurations. The former give rise to anomalous Hall conductivities (AHC) that are found to be extremely anisotropic. For the planar cases the AHC is connected with Weyl points in the energy-band structure. If this case were observable in Mn3Ge, a large AHC of about σzx≈ 900 (Ω \\text{cm})-1 should be expected. However, in Mn3Ge it is the non-planar configuration that is energetically favored, in which case it gives rise to an AHC of σxy≈ 100 (Ω \\text{cm})-1 . The non-planar configuration allows a quantitative evaluation of the topological Hall effect that is seen to determine this value of σxy to a large extent. For Mn3Sn it is the planar configurations that are predicted to be observable. In this case the AHC can be as large as σyz≈250 (Ω \\text{cm})-1 .

  4. Anomalous transport effects in magnetically-confined plasma columns

    International Nuclear Information System (INIS)

    The evolution of density structure in a magnetized plasma column is analyzed accounting for anomalous diffusion due to the lower hybrid drift instability. The plasma column is found to be divided into regions of classical, anomalous, and intermediate diffusivity. The bulk behavior, described in terms of radial confinement time, depends most sensitively upon the particle line density (ion/cm). For broad plasmas (large line density), the transport is characteristic of classical diffusion, and for slender plasmas (small line density) the transport is characteristic of anomalous diffusion. For intermediate line densities, the transport undertakes a rapid transition from classical to anomalous. Correlations between the theoretical results and past experiments are described

  5. The quantum anomalous Hall effect in kagome lattices

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Zhiyong, E-mail: zyzhang@nju.edu.cn [Department of Physics, Nanjing University, Nanjing 210093 (China)

    2011-09-14

    The quantum anomalous Hall (QAH) effect in kagome lattices is investigated in the presence of both Rashba spin-orbit coupling and an exchange field. In addition to the gap at the Dirac points as found in graphene, a new topological energy gap is opened at the {Gamma} point. With the Fermi energy lying in the first gap, the Chern number c = 2 as in graphene, whereas with it lying in the second one, c = 1. The distribution of Berry curvature is obtained to reveal the nontrivial topological properties in momentum space. For stripes with 'armchair' and 'zigzag' edges, the topological characteristics of gapless edge states on the genus g = 2 Riemann surface are studied. The obtained nonzero winding numbers also demonstrate the QAH effect. (paper)

  6. Precise quantization of anomalous Hall effect near zero magnetic field

    Energy Technology Data Exchange (ETDEWEB)

    Bestwick, A. J. [Stanford Univ., Stanford, CA (United States); SLAC National Accelerator Lab., Menlo Park, CA (United States); Fox, E. J. [Stanford Univ., Stanford, CA (United States); SLAC National Accelerator Lab., Menlo Park, CA (United States); Kou, Xufeng [Univ. of California, Los Angeles, CA (United States); Pan, Lei [Univ. of California, Los Angeles, CA (United States); Wang, Kang L. [Univ. of California, Los Angeles, CA (United States); Goldhaber-Gordon, D. [Stanford Univ., Stanford, CA (United States); SLAC National Accelerator Lab., Menlo Park, CA (United States)

    2015-05-04

    In this study, we report a nearly ideal quantum anomalous Hall effect in a three-dimensional topological insulator thin film with ferromagnetic doping. Near zero applied magnetic field we measure exact quantization in the Hall resistance to within a part per 10,000 and a longitudinal resistivity under 1 Ω per square, with chiral edge transport explicitly confirmed by nonlocal measurements. Deviations from this behavior are found to be caused by thermally activated carriers, as indicated by an Arrhenius law temperature dependence. Using the deviations as a thermometer, we demonstrate an unexpected magnetocaloric effect and use it to reach near-perfect quantization by cooling the sample below the dilution refrigerator base temperature in a process approximating adiabatic demagnetization refrigeration.

  7. Anomalous Nernst Effect of Perpendicularly Magnetic Anisotropy TbFeCo Thin Films

    Science.gov (United States)

    Ando, Ryo; Komine, Takashi; Hasegawa, Yasuhiro

    2016-07-01

    In this study, we investigated anomalous Nernst effect (ANE) of perpendicularly magnetized TbFeCo thin films with various Tb content, and especially studied the relation between ANE and anomalous Hall effect. As a result, the hysteresis of anomalous Nernst coefficient showed the same behavior as that of anomalous Hall resistivity, and the sign of anomalous Nernst coefficient was consistent with that of anomalous Hall voltage in any Tb content, whereas the Seebeck coefficient and the resistivity were almost constant even if the applied magnetic field was varied. Taking into account of thermoelectric coefficient tensor, it was revealed that the off-diagonal thermopower corresponding to the ANE in TbFeCo thin films is the product of Hall angle and Seebeck coefficient.

  8. Detecting topological phases in silicene by anomalous Nernst effect

    Science.gov (United States)

    Xu, Yafang; Zhou, Xingfei; Jin, Guojun

    2016-05-01

    Silicene undergoes various topological phases under the interplay of intrinsic spin-orbit coupling, perpendicular electric field, and off-resonant light. We propose that the abundant topological phases can be distinguished by measuring the Nernst conductivity even at room temperature, and their phase boundaries can be determined by differentiating the charge and spin Nernst conductivities. By modulating the electric and light fields, pure spin polarized, valley polarized, and even spin-valley polarized Nernst currents can be generated. As Nernst conductivity is zero for linear polarized light, silicene can act as an optically controlled spin and valley field-effect transistor. Similar investigations can be extended from silicene to germanene and stanene, and a comparison is made for the anomalous thermomagnetic figure of merits between them. These results will facilitate potential applications in spin and valley caloritronics.

  9. Measurement of the velocity skin effect

    Energy Technology Data Exchange (ETDEWEB)

    Thurmond, L.E.; Ahrens, B.K.; Barber, J.P. (SEDI-MET, Inc., Albuquerque, NM (United States))

    1991-01-01

    The velocity skin effect is a maldistribution of current in a moving slider and substrate due to diffusion effects in the substrate material. This effect is important in armature design. The effect causes most of the current to flow through the rear of the armature. This may result in structural failure of the armature due to heating and nonuniform pressure on the armature. In this paper, the authors describe a series of experiments that we performed to measure the velocity skin effect directly. The authors used a rotating disk device to simulate railgun conditions up to 50 m/s. The authors observed the velocity skin effect under our experimental conditions.

  10. Gamma Radiation Effects on Peanut Skin Antioxidants

    OpenAIRE

    de Camargo, Adriano Costa; Vieira, Thais Maria Ferreira de Souza; Regitano-d’Arce, Marisa Aparecida Bismara; Calori-Domingues, Maria Antonia; Solange Guidolin CANNIATTI-BRAZACA

    2012-01-01

    Peanut skin, which is removed in the peanut blanching process, is rich in bioactive compounds with antioxidant properties. The aims of this study were to measure bioactive compounds in peanut skins and evaluate the effect of gamma radiation on their antioxidant activity. Peanut skin samples were treated with 0.0, 5.0, 7.5, or 10.0 kGy gamma rays. Total phenolics, condensed tannins, total flavonoids, and antioxidant activity were evaluated. Extracts obtained from the peanut skins were added to...

  11. Quantum anomalous Hall effect in magnetic topological insulators

    Science.gov (United States)

    Wang, Jing; Lian, Biao; Zhang, Shou-Cheng

    2015-12-01

    The search for topologically non-trivial states of matter has become an important goal for condensed matter physics. Here, we give a theoretical introduction to the quantum anomalous Hall (QAH) effect based on magnetic topological insulators in two-dimensions (2D) and three-dimensions (3D). In 2D topological insulators, magnetic order breaks the symmetry between the counter-propagating helical edge states, and as a result, the quantum spin Hall effect can evolve into the QAH effect. In 3D, magnetic order opens up a gap for the topological surface states, and chiral edge state has been predicted to exist on the magnetic domain walls. We present the phase diagram in thin films of a magnetic topological insulator and review the basic mechanism of ferromagnetic order in magnetically doped topological insulators. We also review the recent experimental observation of the QAH effect. We discuss more recent theoretical work on the coexistence of the helical and chiral edge states, multi-channel chiral edge states, the theory of the plateau transition, and the thickness dependence in the QAH effect.

  12. Competing-fluctuation-induced anomalous magnetocaloric effects in perovskite manganites

    Science.gov (United States)

    Sakai, Hideaki; Taguchi, Yasujiro; Tokura, Yoshinori

    2010-03-01

    A magnetocaloric (MC) effect refers to the isothermal entropy change induced by applying (or removing) a magnetic field to the materials, which is a performance index of the magnetic refrigeration technology. In this study, the variation of MC effects has been systematically investigated for colossal magnetoresistive manganites R0.6Sr0.4MnO3 (R=La-Gd) by controlling the R-dependent one-electron bandwidth. With decreasing the bandwidth, the temperature profile of entropy change exhibits a larger peak at the ferromagnetic transition temperature and a steeper drop below it, due to the first-order nature of the transition promoted by a competing charge-orbital ordering instability. For the smallest-bandwidth systems adjacent to the metal- insulator phase boundary, a rectangular-shaped profile for the entropy change emerges with an anomalously wide temperature range. Model calculations have indicated that the bicritical fluctuation enhanced in the phase-competing region has a strong impact on such MC features [1]. [1] H. Sakai et al., J. Phys. Soc. Jpn. 78, 113708 (2009).

  13. Robust quantum anomalous Hall effect in ferromagnetic transition metal halides

    CERN Document Server

    Huang, Chengxi; Wu, Haiping; Deng, Kaiming; Jena, Puru; Kan, Erjun

    2016-01-01

    The quantum anomalous Hall (QAH) effect is a novel topological spintronic phenomenon arising from inherent magnetization and spin-orbit coupling. Various theoretical and experimental efforts have been devoted in search of robust intrinsic QAH insulators. However, up to now, it has only been observed in Cr or V doped (Bi,Sb)2Te3 film in experiments with very low working temperature. Based on the successful synthesis of transition metal halides, we use first-principles calculations to predict that RuI3 monolayer is an intrinsic ferromagnetic QAH insulator with a topologically nontrivial global band gap of 11 meV. This topologically nontrivial band gap at the Fermi level is due to its crystal symmetry, thus the QAH effect is robust. Its Curie temperature, estimated to be ~360 K using Monte-Carlo simulation, is above room temperature and higher than most of two-dimensional ferromagnetic thin films. We also discuss the manipulation of its exchange energy and nontrivial band gap by applying in-plane strain. Our wor...

  14. Eczema's Effects More Than Skin Deep

    Science.gov (United States)

    ... of eczema and its effect on the skin's appearance may contribute to a greater risk of mental health disorders, such as anxiety and depression, Silverberg said. Controlling flare-ups of eczema symptoms ...

  15. Skin Exposures & Effects in the Workplace

    Science.gov (United States)

    ... message, please visit this page: About CDC.gov . Workplace Safety & Health Topics Skin Exposures and Effects Recommendations ... Pinterest Twitter YouTube NIOSH Homepage NIOSH A-Z Workplace Safety & Health Topics Publications and Products Programs Contact ...

  16. Field-effect modulation of anomalous Hall effect in diluted ferromagnetic topological insulator epitaxial films

    Science.gov (United States)

    Chang, CuiZu; Liu, MinHao; Zhang, ZuoCheng; Wang, YaYu; He, Ke; Xue, QiKun

    2016-03-01

    High quality chromium (Cr) doped three-dimensional topological insulator (TI) Sb2Te3 films are grown via molecular beam epitaxy on heat-treated insulating SrTiO3 (111) substrates. We report that the Dirac surface states are insensitive to Cr doping, and a perfect robust long-range ferromagnetic order is unveiled in epitaxial Sb2- x Cr x Te3 films. The anomalous Hall effect is modulated by applying a bottom gate, contrary to the ferromagnetism in conventional diluted magnetic semiconductors (DMSs), here the coercivity field is not significantly changed with decreasing carrier density. Carrier-independent ferromagnetism heralds Sb2- x Cr x Te3 films as the base candidate TI material to realize the quantum anomalous Hall (QAH) effect. These results also indicate the potential of controlling anomalous Hall voltage in future TI-based magneto-electronics and spintronics.

  17. Skin thickness effects on in vivo LXRF

    International Nuclear Information System (INIS)

    The analysis of lead concentration in bone utilizing LXRF can be adversely effected by overlying issue. A quantitative measure of the attenuation of the 10.5 keV Pb L a x-ray signal by skin and skin equivalent plastic has been conducted. Concentration ranges in plaster of Paris and goat bone from 7 to 90 ppm with attenuators of Lucite reg-sign and pig skin were examined. It is concluded that no quantitative or semi quantitative analysis can be achieved if overlying sue thickness exceeds 3 mm for Ph concentrations of less than 30 porn Ph in bone

  18. Carrier-independent ferromagnetism and giant anomalous Hall effect in magnetic topological insulator

    OpenAIRE

    Chang, Cui-Zu; Zhang, Jin-song; Liu, Min-Hao; Zhang, Zuo-Cheng; Feng, Xiao; Li, Kang; Wang, Li-Li; Chen, Xi; Dai, Xi; Fang, Zhong; Qi, Xiao-Liang; Zhang, Shou-Cheng; Wang, Yayu; He, Ke; Ma, Xu-Cun

    2011-01-01

    Breaking the time-reversal symmetry of a topological insulator (TI) by ferromagnetism can induce exotic magnetoelectric phenomena such as quantized anomalous Hall (QAH) effect. Experimental observation of QAH effect in a magnetically doped TI requires ferromagnetism not relying on the charge carriers. We have realized the ferromagnetism independent of both polarity and density of carriers in Cr-doped BixSb2-xTe3 thin films grown by molecular beam epitaxy. Meanwhile, the anomalous Hall effect ...

  19. Localization correction to the anomalous Hall effect in amorphous CoFeB thin films

    Institute of Scientific and Technical Information of China (English)

    丁进军; 吴少兵; 杨晓非; 朱涛

    2015-01-01

    An obvious weak localization correction to anomalous Hall conductance (AHC) in very thin CoFeB film is reported. We find that both the weak localization to AHC and the mechanism of anomalous Hall effect are related to the CoFeB thickness. When the film is thicker than 3 nm, the side jump mechanism dominates and the weak localization to AHC vanishes. For very thin CoFeB films, both the side jump and skew scattering mechanisms contribute to the anomalous Hall effect, and the weak localization correction to AHC is observed.

  20. Magnetic Topological Insulators and Quantum Anomalous Hall Effect

    Science.gov (United States)

    Kou, Xufeng

    The engineering of topological surface states is a key to realize applicable devices based on topological insulators (TIs). Among various proposals, introducing magnetic impurities into TIs has been proven to be an effective way to open a surface gap and integrate additional ferromagnetism with the original topological order. In this Dissertation, we study both the intrinsic electrical and magnetic properties of the magnetic TI thin films grown by molecular beam epitaxy. By doping transition element Cr into the host tetradymite-type V-VI semiconductors, we achieve robust ferromagnetic order with a strong perpendicular magnetic anisotropy. With additional top-gating capability, we realize the electric-field-controlled ferromagnetism in the magnetic TI systems, and demonstrate such magneto-electric effects can be effectively manipulated, depending on the interplays between the band topology, magnetic exchange coupling, and structural engineering. Most significantly, we report the observation of quantum anomalous Hall effect (QAHE) in the Cr-doped (BiSb)2Te3 samples where dissipationless chiral edge conduction is realized in the macroscopic millimeter-size devices without the presence of any external magnetic field, and the stability of the quantized Hall conductance of e2/h is well-maintained as the film thickness varies across the 2D hybridization limit. With additional quantum confinement, we discover the metal-to-insulator switching between two opposite QAHE states, and reveal the universal QAHE phase diagram in the thin magnetic TI samples. In addition to the uniform magnetic TIs, we further investigate the TI/Cr-doped TI bilayer structures prepared by the modulation-doped growth method. By controlling the magnetic interaction profile, we observe the Dirac hole-mediated ferromagnetism and develop an effective way to manipulate its strength. Besides, the giant spin-orbit torque in such magnetic TI-based heterostructures enables us to demonstrate the current

  1. Thickness Dependence of the Quantum Anomalous Hall Effect in Magnetic Topological Insulator Films.

    Science.gov (United States)

    Feng, Xiao; Feng, Yang; Wang, Jing; Ou, Yunbo; Hao, Zhenqi; Liu, Chang; Zhang, Zuocheng; Zhang, Liguo; Lin, Chaojing; Liao, Jian; Li, Yongqing; Wang, Li-Li; Ji, Shuai-Hua; Chen, Xi; Ma, Xucun; Zhang, Shou-Cheng; Wang, Yayu; He, Ke; Xue, Qi-Kun

    2016-08-01

    The evolution of the quantum anomalous Hall effect with the thickness of Cr-doped (Bi,Sb)2 Te3 magnetic topological insulator films is studied, revealing how the effect is caused by the interplay of the surface states, band-bending, and ferromagnetic exchange energy. Homogeneity in ferromagnetism is found to be the key to high-temperature quantum anomalous Hall material. PMID:27166762

  2. Anomalous effects due to the inertial anti-gravitational potential of the sun

    OpenAIRE

    Khokhlov, D. L.

    2007-01-01

    It is introduced inertial anti-gravitational potential into the theory of gravity to stop gravitational collapse at the nuclear density and thus prevent singularities. It is considered effective gravity which includes Newtonian potential and inertial anti-gravitational potential. It is investigated footprints of the effective gravity in the solar system. The inertial anti-gravitational potential of the sun allows to explain the anomalous acceleration of Pioneer 10 and 11, the anomalous increa...

  3. Gamma Radiation Effects on Peanut Skin Antioxidants

    Directory of Open Access Journals (Sweden)

    Adriano Costa de Camargo

    2012-03-01

    Full Text Available Peanut skin, which is removed in the peanut blanching process, is rich in bioactive compounds with antioxidant properties. The aims of this study were to measure bioactive compounds in peanut skins and evaluate the effect of gamma radiation on their antioxidant activity. Peanut skin samples were treated with 0.0, 5.0, 7.5, or 10.0 kGy gamma rays. Total phenolics, condensed tannins, total flavonoids, and antioxidant activity were evaluated. Extracts obtained from the peanut skins were added to refined-bleached-deodorized (RBD soybean oil. The oxidative stability of the oil samples was determined using the Oil Stability Index method and compared to a control and synthetic antioxidants (100 mg/kg BHT and 200 mg/kg TBHQ. Gamma radiation changed total phenolic content, total condensed tannins, total flavonoid content, and the antioxidant activity. All extracts, gamma irradiated or not, presented increasing induction period (h, measured by the Oil Stability Index method, when compared with the control. Antioxidant activity of the peanut skins was higher than BHT. The present study confirmed that gamma radiation did not affect the peanut skin extracts’ antioxidative properties when added to soybean oil.

  4. Gamma radiation effects on peanut skin antioxidants.

    Science.gov (United States)

    de Camargo, Adriano Costa; de Souza Vieira, Thais Maria Ferreira; Regitano-D'Arce, Marisa Aparecida Bismara; Calori-Domingues, Maria Antonia; Canniatti-Brazaca, Solange Guidolin

    2012-01-01

    Peanut skin, which is removed in the peanut blanching process, is rich in bioactive compounds with antioxidant properties. The aims of this study were to measure bioactive compounds in peanut skins and evaluate the effect of gamma radiation on their antioxidant activity. Peanut skin samples were treated with 0.0, 5.0, 7.5, or 10.0 kGy gamma rays. Total phenolics, condensed tannins, total flavonoids, and antioxidant activity were evaluated. Extracts obtained from the peanut skins were added to refined-bleached-deodorized (RBD) soybean oil. The oxidative stability of the oil samples was determined using the Oil Stability Index method and compared to a control and synthetic antioxidants (100 mg/kg BHT and 200 mg/kg TBHQ). Gamma radiation changed total phenolic content, total condensed tannins, total flavonoid content, and the antioxidant activity. All extracts, gamma irradiated or not, presented increasing induction period (h), measured by the Oil Stability Index method, when compared with the control. Antioxidant activity of the peanut skins was higher than BHT. The present study confirmed that gamma radiation did not affect the peanut skin extracts' antioxidative properties when added to soybean oil.

  5. Anomalous Hall effect on the surface of topological Kondo insulators

    Science.gov (United States)

    König, E. J.; Ostrovsky, P. M.; Dzero, M.; Levchenko, A.

    2016-07-01

    We calculate the anomalous Hall conductivity σx y of the surface states in cubic topological Kondo insulators. We consider a generic model for the surface states with three Dirac cones on the (001) surface. The Fermi velocity, the Fermi momentum, and the Zeeman energy in different Dirac pockets may be unequal. The microscopic impurity potential mediates mixed intra- and interband extrinsic scattering processes. Our calculation of σx y is based on the Kubo-Streda diagrammatic approach. It includes diffractive skew scattering contributions originating from the rare two-impurity complexes. Remarkably, these contributions yield anomalous Hall conductivity that is independent of impurity concentration, and thus is of the same order as other known extrinsic side jump and skew scattering terms. We discuss various special cases of our results and the experimental relevance of our study in the context of the recent hysteretic magnetotransport data in SmB6 samples.

  6. Higgs mechanism, phase transitions, and anomalous Hall effect in three-dimensional topological superconductors

    Science.gov (United States)

    Nogueira, Flavio S.; Sudbø, Asle; Eremin, Ilya

    2015-12-01

    We demonstrate that the Higgs mechanism in three-dimensional topological superconductors exhibits unique features with experimentally observable consequences. The Higgs model we discuss has two superconducting components and an axionlike magnetoelectric term with the phase difference of the superconducting order parameters playing the role of the axion field. Due to this additional term, quantum electromagnetic and phase fluctuations lead to a robust topologically nontrivial state that holds also in the presence of interactions. In this sense, we show that the renormalization flow of the topologically nontrivial phase cannot be continuously deformed into a topologically nontrivial one. One consequence of our analysis of quantum critical fluctuations is the possibility of having a first-order phase transition in the bulk and a second-order phase transition on the surface. We also explore another consequence of the axionic Higgs electrodynamics, namely, the anomalous Hall effect. In the low-frequency London regime an anomalous Hall effect is induced in the presence of an applied electric field parallel to the surface. This anomalous Hall current is induced by a Lorentz-like force arising from the axion term, and it involves the relative superfluid velocity of the superconducting components. The anomalous Hall current has a negative sign, a situation reminiscent of but quite distinct in physical origin from the anomalous Hall effect observed in high-Tc superconductors. In contrast to the latter, the anomalous Hall effect in topological superconductors is nondissipative and occurs in the absence of vortices.

  7. Theory of the anomalous Hall effect from the Kubo formula and the Dirac equation

    OpenAIRE

    Crépieux, A.; Bruno, P

    2001-01-01

    A model to treat the anomalous Hall effect is developed. Based on the Kubo formalism and on the Dirac equation, this model allows the simultaneous calculation of the skew-scattering and side-jump contributions to the anomalous Hall conductivity. The continuity and the consistency with the weak-relativistic limit described by the Pauli Hamiltonian is shown. For both approaches, Dirac and Pauli, the Feynman diagrams, which lead to the skew-scattering and the side-jump contributions, are underli...

  8. Anomalous $tqZ$ coupling effects in rare B- and K-meson decays

    CERN Document Server

    Li, Xin-Qiang; Yuan, Xing-Bo

    2011-01-01

    As a top-factory, the LHC is performing a direct study of top-quark anomalous FCNC couplings, which are, however, correlated closely with the rare B- and K-meson decays. In this paper, we study the effects of anomalous $tqZ$ (with $q=u,c$) couplings in the rare decays $B_{s,d}\\to \\mu^+\\mu^-$, $B\\to X_s \

  9. Biological effects of rutin on skin aging.

    Science.gov (United States)

    Choi, Seong Jin; Lee, Sung-Nae; Kim, Karam; Joo, Da Hye; Shin, Shanghun; Lee, Jeongju; Lee, Hyun Kyung; Kim, Jihyun; Kwon, Seung Bin; Kim, Min Jung; Ahn, Kyu Joong; An, In-Sook; An, Sungkwan; Cha, Hwa Jun

    2016-07-01

    Rutin, a quercetin glycoside is a member of the bioflavonoid family which is known to possess antioxidant properties. In the present study, we aimed to confirm the anti‑aging effects of rutin on human dermal fibroblasts (HDFs) and human skin. We examined the effects of rutin using a cell viability assay, senescence-associated-β-galactosidase assay, reverse transcription-quantitative polymerase chain reaction, and by measuring reactive oxygen species (ROS) scavenging activity in vitro. To examine the effects of rutin in vivo, rutin‑containing cream was applied to human skin. A double-blind clinical study was conducted in 40 subjects aged between 30-50 years and divided into control and experimental groups. The test material was applied for 4 weeks. After 2 and 4 weeks, dermal density, skin elasticity, the length and area of crow's feet, and number of under-eye wrinkles following the application of either the control or the rutin-containing cream were analyzed. Rutin increased the mRNA expression of collagen, type I, alpha 1 (COL1A1) and decreased the mRNA expression of matrix metallopeptidase 1 (MMP1) in HDFs. We verified that ROS scavenging activity was stimulated by rutin in a dose‑dependent manner and we identified that rutin exerted protective effects under conditions of oxidative stress. Furthermore, rutin increased skin elasticity and decreased the length, area and number of wrinkles. The consequences of human aging are primarily visible on the skin, such as increased wrinkling, sagging and decreased elasticity. Overall, this study demonstrated the biological effects of rutin on ROS-induced skin aging. PMID:27220601

  10. Unconventional scaling of the anomalous Hall effect accompanying electron localization correction in the dirty regime

    KAUST Repository

    Lu, Y. M.

    2013-03-05

    Scaling of the anomalous Hall conductivity to longitudinal conductivity σAH∝σ2xx has been observed in the dirty regime of two-dimensional weak and strong localization regions in ultrathin, polycrystalline, chemically disordered, ferromagnetic FePt films. The relationship between electron transport and temperature reveals a quantitatively insignificant Coulomb interaction in these films, while the temperature dependent anomalous Hall conductivity experiences quantum correction from electron localization. At the onset of this correction, the low-temperature anomalous Hall resistivity begins to be saturated when the thickness of the FePt film is reduced, and the corresponding Hall conductivity scaling exponent becomes 2, which is above the recent unified theory of 1.6 (σAH∝σ1.6xx). Our results strongly suggest that the correction of the electron localization modulates the scaling exponent of the anomalous Hall effect.

  11. Large anomalous Hall effect in a non-collinear antiferromagnet at room temperature.

    Science.gov (United States)

    Nakatsuji, Satoru; Kiyohara, Naoki; Higo, Tomoya

    2015-11-12

    In ferromagnetic conductors, an electric current may induce a transverse voltage drop in zero applied magnetic field: this anomalous Hall effect is observed to be proportional to magnetization, and thus is not usually seen in antiferromagnets in zero field. Recent developments in theory and experiment have provided a framework for understanding the anomalous Hall effect using Berry-phase concepts, and this perspective has led to predictions that, under certain conditions, a large anomalous Hall effect may appear in spin liquids and antiferromagnets without net spin magnetization. Although such a spontaneous Hall effect has now been observed in a spin liquid state, a zero-field anomalous Hall effect has hitherto not been reported for antiferromagnets. Here we report empirical evidence for a large anomalous Hall effect in an antiferromagnet that has vanishingly small magnetization. In particular, we find that Mn3Sn, an antiferromagnet that has a non-collinear 120-degree spin order, exhibits a large anomalous Hall conductivity of around 20 per ohm per centimetre at room temperature and more than 100 per ohm per centimetre at low temperatures, reaching the same order of magnitude as in ferromagnetic metals. Notably, the chiral antiferromagnetic state has a very weak and soft ferromagnetic moment of about 0.002 Bohr magnetons per Mn atom (refs 10, 12), allowing us to switch the sign of the Hall effect with a small magnetic field of around a few hundred oersted. This soft response of the large anomalous Hall effect could be useful for various applications including spintronics--for example, to develop a memory device that produces almost no perturbing stray fields. PMID:26524519

  12. Large anomalous Hall effect in a non-collinear antiferromagnet at room temperature.

    Science.gov (United States)

    Nakatsuji, Satoru; Kiyohara, Naoki; Higo, Tomoya

    2015-11-12

    In ferromagnetic conductors, an electric current may induce a transverse voltage drop in zero applied magnetic field: this anomalous Hall effect is observed to be proportional to magnetization, and thus is not usually seen in antiferromagnets in zero field. Recent developments in theory and experiment have provided a framework for understanding the anomalous Hall effect using Berry-phase concepts, and this perspective has led to predictions that, under certain conditions, a large anomalous Hall effect may appear in spin liquids and antiferromagnets without net spin magnetization. Although such a spontaneous Hall effect has now been observed in a spin liquid state, a zero-field anomalous Hall effect has hitherto not been reported for antiferromagnets. Here we report empirical evidence for a large anomalous Hall effect in an antiferromagnet that has vanishingly small magnetization. In particular, we find that Mn3Sn, an antiferromagnet that has a non-collinear 120-degree spin order, exhibits a large anomalous Hall conductivity of around 20 per ohm per centimetre at room temperature and more than 100 per ohm per centimetre at low temperatures, reaching the same order of magnitude as in ferromagnetic metals. Notably, the chiral antiferromagnetic state has a very weak and soft ferromagnetic moment of about 0.002 Bohr magnetons per Mn atom (refs 10, 12), allowing us to switch the sign of the Hall effect with a small magnetic field of around a few hundred oersted. This soft response of the large anomalous Hall effect could be useful for various applications including spintronics--for example, to develop a memory device that produces almost no perturbing stray fields.

  13. Gamma radiation effects on peanut skin antioxidants

    International Nuclear Information System (INIS)

    Peanut skin, which is removed in the peanut blanching process, is rich in bioactive compounds with antioxidant properties. The viability of using natural sources of antioxidants to replace synthetic antioxidants was assessed. The aims of this study were to measure bioactive compounds in peanut skins and evaluate the effect of gamma radiation on their antioxidant activity. Peanut skin samples were treated with 0.0, 5.0, 7.5, or 10.0 kGy gamma rays at a dose rate of 7.5 kGy/h using a 60Co source. Total phenolics, condensed tannins, total flavonoids, and antioxidant activity were evaluated. Extracts obtained from the peanut skins were added to refined-bleached deodorized (RBD) soybean oil that was free from synthetic antioxidants. The oxidative stability of the oil samples was determined using the Rancimat method and compared to a control and synthetic antioxidants (100 mg/kg BHT and 200 mg/kg TBHQ). Gamma radiation changed total phenolic content, total condensed tannins, total flavonoid content, and the antioxidant activity. Ethanolic extracts, gamma irradiated or not, presented increasing induction period (h), measured by the Rancimat method, when compared with the control. Antioxidant activity of the peanut skins was higher than BHT but lower than THBQ. The present study confirmed that gamma radiation did not affect the peanut skin extracts' antioxidative level when added to soybean oil. The induction period of the control soybean oil was 5.7 h, while soybean oil with added ethanolic peanut skin extract had an induction period of 7.2 h, on average. (author)

  14. Gamma radiation effects on peanut skin antioxidants

    Energy Technology Data Exchange (ETDEWEB)

    Camargo, Adriano Costa de [Centro de Energia Nuclear na Agricultura (CENA/USP), Piracicaba, SP (Brazil); Canniatti-Brazaca, Solange Guidolin; Vieira, Thais Maria Ferreira de Souza; Regitano-d' Arce, Marisa Aparecida Bismara; Calori-Domingues, Maria Antonia, E-mail: sgcbraza@usp.b, E-mail: tvieira@esalq.usp.b, E-mail: mabra@esalq.usp.b, E-mail: macdomin@esalq.usp.b [Escola Superior de Agricultura Luiz de Queiroz (ESALQ/USP), Piracicaba, SP (Brazil). Dept. de Agroindustria, Alimentos e Nutricao

    2011-07-01

    Peanut skin, which is removed in the peanut blanching process, is rich in bioactive compounds with antioxidant properties. The viability of using natural sources of antioxidants to replace synthetic antioxidants was assessed. The aims of this study were to measure bioactive compounds in peanut skins and evaluate the effect of gamma radiation on their antioxidant activity. Peanut skin samples were treated with 0.0, 5.0, 7.5, or 10.0 kGy gamma rays at a dose rate of 7.5 kGy/h using a {sup 60}Co source. Total phenolics, condensed tannins, total flavonoids, and antioxidant activity were evaluated. Extracts obtained from the peanut skins were added to refined-bleached deodorized (RBD) soybean oil that was free from synthetic antioxidants. The oxidative stability of the oil samples was determined using the Rancimat method and compared to a control and synthetic antioxidants (100 mg/kg BHT and 200 mg/kg TBHQ). Gamma radiation changed total phenolic content, total condensed tannins, total flavonoid content, and the antioxidant activity. Ethanolic extracts, gamma irradiated or not, presented increasing induction period (h), measured by the Rancimat method, when compared with the control. Antioxidant activity of the peanut skins was higher than BHT but lower than THBQ. The present study confirmed that gamma radiation did not affect the peanut skin extracts' antioxidative level when added to soybean oil. The induction period of the control soybean oil was 5.7 h, while soybean oil with added ethanolic peanut skin extract had an induction period of 7.2 h, on average. (author)

  15. The effect of interfacial intermixing on magnetization and anomalous Hall effect in Co/Pd multilayers

    KAUST Repository

    Guo, Zaibing

    2015-05-01

    The effect of interfacial intermixing on magnetization and anomalous Hall effect (AHE) in Co/Pd multilayers is studied by using rapid thermal annealing to enhance the interfacial diffusion. The dependence of saturation magnetization and coercivity on the temperature of rapid thermal annealing at 5 K is discussed. It is found that AHE is closely related to the relative thickness of the Co and Pd layers. Localized paramagnetism has been observed which destroys AHE, while AHE can be enhanced by annealing.

  16. Effects of climate changes on skin diseases.

    Science.gov (United States)

    Balato, Nicola; Megna, Matteo; Ayala, Fabio; Balato, Anna; Napolitano, Maddalena; Patruno, Cataldo

    2014-02-01

    Global climate is changing at an extraordinary rate. Climate change (CC) can be caused by several factors including variations in solar radiation, oceanic processes, and also human activities. The degree of this change and its impact on ecological, social, and economical systems have become important matters of debate worldwide, representing CC as one of the greatest challenges of the modern age. Moreover, studies based on observations and predictive models show how CC could affect human health. On the other hand, only a few studies focus on how this change may affect human skin. However, the skin is the most exposed organ to environment; therefore, it is not surprising that cutaneous diseases are inclined to have a high sensitivity to climate. The current review focuses on the effects of CC on skin diseases showing the numerous factors that are contributing to modify the incidence, clinical pattern and natural course of some dermatoses. PMID:24404995

  17. Anomalous Hall effect in Fe/Gd bilayers

    KAUST Repository

    Xu, W. J.

    2010-04-01

    Non-monotonic dependence of anomalous Hall resistivity on temperature and magnetization, including a sign change, was observed in Fe/Gd bilayers. To understand the intriguing observations, we fabricated the Fe/Gd bilayers and single layers of Fe and Gd simultaneously. The temperature and field dependences of longitudinal resistivity, Hall resistivity and magnetization in these films have also been carefully measured. The analysis of these data reveals that these intriguing features are due to the opposite signs of Hall resistivity/or spin polarization and different Curie temperatures of Fe and Gd single-layer films. Copyright (C) EPLA, 2010

  18. Role of antioxidants in the skin: anti-aging effects.

    Science.gov (United States)

    Masaki, Hitoshi

    2010-05-01

    Intracellular and extracellular oxidative stress initiated by reactive oxygen species (ROS) advance skin aging, which is characterized by wrinkles and atypical pigmentation. Because UV enhances ROS generation in cells, skin aging is usually discussed in relation to UV exposure. The use of antioxidants is an effective approach to prevent symptoms related to photo-induced aging of the skin. In this review, the mechanisms of ROS generation and ROS elimination in the body are summarized. The effects of ROS generated in the skin and the roles of ROS in altering the skin are also discussed. In addition, the effects of representative antioxidants on the skin are summarized with a focus on skin aging.

  19. Anomalous transport effects and possible environmental symmetry violation in heavy-ion collisions

    International Nuclear Information System (INIS)

    The heavy-ion collision provides a unique many-body environment where local domains of strongly interacting chiral medium may occur and in a sense allow environmental symmetry 'violation' phenomena. For example, certain anomalous transport processes, forbidden in usual medium, become possible in such domains. We briefly review recent progress in both the theoretical understanding and experimental search of various anomalous transport effects (such as the chiral magnetic effect, chiral separation effect, chiral electric separation effect, chiral electric/magnetic waves, etc.) in the hot QCD fluid formed by such collisions. (author)

  20. Anomalous transport effects and possible environmental symmetry 'violation' in heavy-ion collisions

    Indian Academy of Sciences (India)

    Jinfeng Liao

    2015-05-01

    The heavy-ion collision provides a unique many-body environment where local domains of strongly interacting chiral medium may occur and in a sense allow environmental symmetry 'violation' phenomena. For example, certain anomalous transport processes, forbidden in usual medium, become possible in such domains. We briefly review recent progress in both the theoretical understanding and experimental search of various anomalous transport effects (such as the chiral magnetic effect, chiral separation effect, chiral electric separation effect, chiral electric/magnetic waves, etc.) in the hot QCD fluid formed by such collisions.

  1. Effect of Ethanol Pretreatment on Skin Permeation of Drugs

    OpenAIRE

    堀田,大介; 藤堂, 浩明; 杉林, 堅次

    2012-01-01

    It has been demonstrated that ethanol (EtOH) can enhance skin permeation of drugs when simultaneously applied with drugs. However, only a few studies have reported on the pretreatment effect of EtOH on skin permeations. In this study, the pretreatment effects of EtOH on skin permeation of drugs were investigated by measuring changes in skin permeation and electrical skin resistance. Permeabilities of deuterium oxide (D2O), isosorbide mononitrate (ISMN), isosorbide dinitrate (ISDN), calcein so...

  2. Shark skin effect in creeping films

    CERN Document Server

    Scholle, M

    2006-01-01

    If a body in a stream is provided with small ridges aligned in the local flow direction, a remarkable drag reduction can be reached under turbulent flow conditions. This surprising phenomenon is called the 'shark skin effect'. We demonstrate, that a reduction of resistance can also be reached in creeping flows if the ridges are aligned perpendicular to the flow direction. We especially consider in gravity-driven film flows the effect of the bottom topography on the mean transport velocity.

  3. Absence of anomalous Nernst effect in spin Seebeck effect of Pt/YIG

    Directory of Open Access Journals (Sweden)

    B. F. Miao

    2016-01-01

    Full Text Available The Pt/YIG structure has been widely used to study spin Seebeck effect (SSE, inverse spin Hall effect, and other pure spin current phenomena. However, the magnetic proximity effect in Pt when in contact with YIG, and the potential anomalous Nernst effect (ANE may compromise the spin current phenomena in Pt/YIG. By inserting a Cu layer of various thicknesses between Pt and YIG, we have separated the signals from the SSE and that of the ANE. It is demonstrated that the thermal voltage in Pt/YIG mainly comes from spin current due to the longitudinal SSE with negligible contribution from the ANE.

  4. Absence of anomalous Nernst effect in spin Seebeck effect of Pt/YIG

    Science.gov (United States)

    Miao, B. F.; Huang, S. Y.; Qu, D.; Chien, C. L.

    2016-01-01

    The Pt/YIG structure has been widely used to study spin Seebeck effect (SSE), inverse spin Hall effect, and other pure spin current phenomena. However, the magnetic proximity effect in Pt when in contact with YIG, and the potential anomalous Nernst effect (ANE) may compromise the spin current phenomena in Pt/YIG. By inserting a Cu layer of various thicknesses between Pt and YIG, we have separated the signals from the SSE and that of the ANE. It is demonstrated that the thermal voltage in Pt/YIG mainly comes from spin current due to the longitudinal SSE with negligible contribution from the ANE.

  5. Absence of anomalous Nernst effect in spin Seebeck effect of Pt/YIG

    Energy Technology Data Exchange (ETDEWEB)

    Miao, B. F., E-mail: bfmiao@nju.edu.cn [National Laboratory of Solid State Microstructures and Department of Physics, Nanjing University, Nanjing 210093 (China); Department of Physics and Astronomy, Johns Hopkins University, Baltimore, MD 21218 (United States); Huang, S. Y. [Department of Physics and Astronomy, Johns Hopkins University, Baltimore, MD 21218 (United States); Department of Physics, National Taiwan University, Taipei 10617, Taiwan (China); Qu, D.; Chien, C. L., E-mail: clchien@jhu.edu [Department of Physics and Astronomy, Johns Hopkins University, Baltimore, MD 21218 (United States)

    2016-01-15

    The Pt/YIG structure has been widely used to study spin Seebeck effect (SSE), inverse spin Hall effect, and other pure spin current phenomena. However, the magnetic proximity effect in Pt when in contact with YIG, and the potential anomalous Nernst effect (ANE) may compromise the spin current phenomena in Pt/YIG. By inserting a Cu layer of various thicknesses between Pt and YIG, we have separated the signals from the SSE and that of the ANE. It is demonstrated that the thermal voltage in Pt/YIG mainly comes from spin current due to the longitudinal SSE with negligible contribution from the ANE.

  6. Effect of interstitial low level laser stimulation in skin density

    Science.gov (United States)

    Jang, Seulki; Ha, Myungjin; Lee, Sangyeob; Yu, Sungkon; Park, Jihoon; Radfar, Edalat; Hwang, Dong Hyun; Lee, Han A.; Kim, Hansung; Jung, Byungjo

    2016-03-01

    As the interest in skin was increased, number of studies on skin care also have been increased. The reduction of skin density is one of the symptoms of skin aging. It reduces elasticity of skin and becomes the reason of wrinkle formation. Low level laser therapy (LLLT) has been suggested as one of the effective therapeutic methods for skin aging as in hasten to change skin density. This study presents the effect of a minimally invasive laser needle system (MILNS) (wavelength: 660nm, power: 20mW) in skin density. Rabbits were divided into three groups. Group 1 didn't receive any laser stimulation as a control group. Group 2 and 3 as test groups were exposed to MILNS with energy of 8J and 6J on rabbits' dorsal side once a week, respectively. Skin density of rabbits was measured every 12 hours by using an ultrasound skin scanner.

  7. Sun’s effect on skin

    Science.gov (United States)

    The skin uses sunlight to help manufacture vitamin D, which is important for normal bone formation. But sometimes its ultraviolet light can be ... the pigment melanin. Melanin protects skin from the sun's ultraviolet rays, which can burn the skin, and ...

  8. Inverse Spin Hall Effect and Anomalous Hall Effect in a Two-Dimensional Electron Gas

    OpenAIRE

    Schwab, Peter; Raimondi, Roberto; Gorini, Cosimo

    2010-01-01

    We study the coupled dynamics of spin and charge currents in a two-dimensional electron gas in the transport diffusive regime. For systems with inversion symmetry there are established relations between the spin Hall effect, the anomalous Hall effect and the inverse spin Hall effect. However, in two-dimensional electron gases of semiconductors like GaAs, inversion symmetry is broken so that the standard arguments do not apply. We demonstrate that in the presence of a Rashba type of spin-orbit...

  9. Spontaneous magnetization and anomalous Hall effect in an emergent Dice lattice

    Science.gov (United States)

    Dutta, Omjyoti; Przysiężna, Anna; Zakrzewski, Jakub

    2015-06-01

    Ultracold atoms in optical lattices serve as a tool to model different physical phenomena appearing originally in condensed matter. To study magnetic phenomena one needs to engineer synthetic fields as atoms are neutral. Appropriately shaped optical potentials force atoms to mimic charged particles moving in a given field. We present the realization of artificial gauge fields for the observation of anomalous Hall effect. Two species of attractively interacting ultracold fermions are considered to be trapped in a shaken two dimensional triangular lattice. A combination of interaction induced tunneling and shaking can result in an emergent Dice lattice. In such a lattice the staggered synthetic magnetic flux appears and it can be controlled with external parameters. The obtained synthetic fields are non-Abelian. Depending on the tuning of the staggered flux we can obtain either anomalous Hall effect or its quantized version. Our results are reminiscent of Anomalous Hall conductivity in spin-orbit coupled ferromagnets.

  10. Scaling of anomalous hall effect in amorphous CoFeB Films with accompanying quantum correction

    KAUST Repository

    Zhang, Yan

    2015-05-08

    Scaling of anomalous Hall effect in amorphous CoFeB films with thickness ranging from 2 to 160 nm have been investigated. We have found that the scaling relationship between longitudinal (ρxx) and anomalous Hall (ρAH) resistivity is distinctly different in the Bloch and localization regions. For ultrathin CoFeB films, the sheet resistance (Rxx) and anomalous Hall conductance (GAH) received quantum correction from electron localization showing two different scaling relationships at different temperature regions. In contrast, the thicker films show a metallic conductance, which have only one scaling relationship in the entire temperature range. Furthermore, in the dirty regime of localization regions, an unconventional scaling relationship View the MathML sourceσAH∝σxxα with α=1.99 is found, rather than α=1.60 predicted by the unified theory.

  11. Anomalous Triple Gauge Couplings in the Effective Field Theory Approach at the LHC

    CERN Document Server

    Falkowski, Adam; Greljo, Admir; Marzocca, David; Son, Minho

    2016-01-01

    We discuss how to perform consistent extractions of anomalous triple gauge couplings (aTGC) from electroweak boson pair production at the LHC in the Standard Model Effective Field Theory (SMEFT). After recasting recent ATLAS and CMS searches in $pp\\to WZ (WW) \\to \\ell' \

  12. Switching field distribution of arrays of Co-Pt Nanodots determined by anomalous hall effect measurements

    NARCIS (Netherlands)

    Delalande, M.; Engelen, J.B.C.; Febre, le A.J.; Abelmann, L.; Lodder, J.C.

    2008-01-01

    Anomalous Hall Effect (AHE) measurements have previously been used to measure the magnetization of L10-FePt [1] and Co/Pt multilayer nanodots [2]. The high sensitivity allows us to measure the magnetization reversal behaviour of sub-100-nm dots. In this work, we investigate the magnetization reversa

  13. Anomalous Hall effects in pseudo-single-crystal γ'-Fe4N thin films

    Science.gov (United States)

    Kabara, Kazuki; Tsunoda, Masakiyo; Kokado, Satoshi

    2016-05-01

    The anomalous Hall effects (AHE) were investigated at various temperatures for the pseudo-single-crystal Fe4N films, deposited on MgO substrates with changing the degree of order (S) of the nitrogen site. Both the anomalous Hall resistivity and the longitudinal resistivity simply decrease with lowering temperature for all the specimens. The AHE of the Fe4N films is presumed to arise from an intrinsic mechanism because of the relationship between the anomalous Hall resistivity and longitudinal resistivity. The anomalous Hall conductivity, σAH, exhibits a specific behavior at low temperature. In the case of the film with S = 0.93, the σAH drastically drops below 50 K, while it simply increases with lowering temperature in the range of 50-300 K. This low-temperature anomaly decays with decreasing S of the film and nearly vanishes in the films with low S. The threshold temperature and the dependence on S of the low-temperature anomaly of the σAH well correspond to those of the anisotropic magnetoresistance effects in the Fe4N films, reported in the literatures. From these results, it is suggested that the low-temperature anomaly of the σAH originates from the crystal field effect which reflects the structural transformation from a cubic to a tetragonal symmetry below 50 K and provides a modulation of the orbital angular momentum of the 3d orbitals at the Fermi level.

  14. Understanding Engineered Nanomaterial Skin Interactions and the Modulatory Effects of UVR Skin Exposure

    OpenAIRE

    Jatana, Samreen; DeLouise, Lisa A.

    2013-01-01

    The study of engineered nanomaterials for the development of technological applications, nanomedicine, and nano-enabled consumer products is an ever expanding discipline as is the concern over the impact of nanotechnology on human environmental health and safety. In this review we discuss the current state of understanding of nanomaterial skin interactions with a specific emphasis on the effects of ultra-violet radiation (UVR) skin exposure. Skin is the largest organ of the body and is typica...

  15. Prospect of quantum anomalous Hall and quantum spin Hall effect in doped kagome lattice Mott insulators

    OpenAIRE

    Daniel Guterding; Jeschke, Harald O.; Roser Valentí

    2015-01-01

    Electronic states with non-trivial topology host a number of novel phenomena with potential for revolutionizing information technology. The quantum anomalous Hall effect provides spin-polarized dissipation-free transport of electrons, while the quantum spin Hall effect in combination with superconductivity has been proposed as the basis for realizing decoherence-free quantum computing. We introduce a new strategy for realizing these effects, namely by hole and electron doping kagome lattice M...

  16. Quantized topological magnetoelectric effect of the zero-plateau quantum anomalous Hall state

    OpenAIRE

    Jing WANG; Lian, Biao; Qi, Xiao-Liang; Zhang, Shou-Cheng

    2015-01-01

    Topological magnetoelectric effect in a three-dimensional topological insulator is a novel phenomenon, where an electric field induces a magnetic field in the same direction, with a universal coefficient of proportionality quantized in units of $e^2/2h$. Here we propose that the topological magnetoelectric effect can be realized in the zero-plateau quantum anomalous Hall state of magnetic topological insulators or ferromagnet-topological insulator heterostructure. The finite-size effect is al...

  17. Artificial ferroelectricity due to anomalous Hall effect in magnetic tunnel junctions

    OpenAIRE

    Vedyayev, A.; Ryzhanova, N.; Strelkov, N.; Dieny, B

    2012-01-01

    We theoretically investigated Anomalous Hall Effect (AHE) and Spin Hall Effect (SHE) transversally to the insulating spacer O, in magnetic tunnel junctions of the form F/O/F where F are ferromagnetic layers and O represents a tunnel barrier. We considered the case of purely ballistic (quantum mechanical) transport, taking into account the assymetric scattering due to spin-orbit interaction in the tunnel barrier. AHE and SHE in the considered case have a surface nature due to proximity effect....

  18. Temperature, pressure, and compositional effects on anomalous or "self" preservation of gas hydrates

    Science.gov (United States)

    Stern, L.A.; Circone, S.; Kirby, S.H.; Durham, W.B.

    2003-01-01

    We previously reported on a thermal regime where pure, polycrystalline methane hydrate is preserved metastably in bulk at up to 75 K above its nominal temperature stability limit of 193 K at 0.1 MPa, following rapid release of the sample pore pressure. Large fractions (>50 vol.%) of methane hydrate can be preserved for 2-3 weeks by this method, reflecting the greatly suppressed rates of dissociation that characterize this "anomalous preservation" regime. This behavior contrasts that exhibited by methane hydrate at both colder (193-240 K) and warmer (272-290 K) isothermal test conditions, where dissociation rates increase monotonically with increasing temperature. Here, we report on recent experiments that further investigate the effects of temperature, pressure, and composition on anomalous preservation behavior. All tests conducted on sI methane hydrate yielded self-consistent results that confirm the highly temperature-sensitive but reproducible nature of anomalous preservation behavior. Temperature-stepping experiments conducted between 250 and 268 K corroborate the relative rates measured previously in isothermal preservation tests, and elevated pore-pressure tests showed that, as expected, dissociation rates are further reduced with increasing pressure. Surprisingly, sII methane-ethane hydrate was found to exhibit no comparable preservation effect when rapidly depressurized at 268 K, even though it is thermodynamically stable at higher temperatures and lower pressures than sI methane hydrate. These results, coupled with SEM imaging of quenched sample material from a variety of dissociation tests, strongly support our earlier arguments that ice-"shielding" effects provided by partial dissociation along hydrate grain surfaces do not serve as the primary mechanism for anomalous preservation. The underlying physical-chemistry mechanism(s) of anomalous preservation remains elusive, but appears to be based more on textural or morphological changes within the hydrate

  19. Adverse and beneficial effects of plant extracts on skin and skin disorders.

    Science.gov (United States)

    Mantle, D; Gok, M A; Lennard, T W

    2001-06-01

    Plants are of relevance to dermatology for both their adverse and beneficial effects on skin and skin disorders respectively. Virtually all cultures worldwide have relied historically, or continue to rely on medicinal plants for primary health care. Approximately one-third of all traditional medicines are for treatment of wounds or skin disorders, compared to only 1-3% of modern drugs. The use of such medicinal plant extracts for the treatment of skin disorders arguably has been based largely on historical/anecdotal evidence, since there has been relatively little data available in the scientific literature, particularly with regard to the efficacy of plant extracts in controlled clinical trials. In this article therefore, adverse and beneficial aspects of medicinal plants relating to skin and skin disorders have been reviewed, based on recently available information from the peer-reviewed scientific literature. Beneficial aspects of medicinal plants on skin include: healing of wounds and burn injuries (especially Aloe vera); antifungal, antiviral, antibacterial and acaricidal activity against skin infections such as acne, herpes and scabies (especially tea tree (Melaleuca alternifolia) oil); activity against inflammatory/immune disorders affecting skin (e.g. psoriasis); and anti-tumour promoting activity against skin cancer (identified using chemically-induced two-stage carcinogenesis in mice). Adverse effects of plants on skin reviewed include: irritant contact dermatitis caused mechanically (spines, irritant hairs) or by irritant chemicals in plant sap (especially members of the Ranunculaceae, Euphorbiaceae and Compositae plant families); phytophotodermatitis resulting from skin contamination by plants containing furocoumarins, and subsequent exposure to UV light (notably members of the Umbelliferae and Rutaceae plant families); and immediate (type I) or delayed hypersensitivity contact reactions mediated by the immune system in individuals sensitized to plants

  20. Sun’s effect on skin

    Science.gov (United States)

    The skin uses sunlight to help manufacture vitamin D, which is important for normal bone formation. But sometimes its ultraviolet light can be ... the pigment melanin. Melanin protects skin from the sun’s ultraviolet rays, which can burn the skin, and ...

  1. Prospect of quantum anomalous Hall and quantum spin Hall effect in doped kagome lattice Mott insulators.

    Science.gov (United States)

    Guterding, Daniel; Jeschke, Harald O; Valentí, Roser

    2016-01-01

    Electronic states with non-trivial topology host a number of novel phenomena with potential for revolutionizing information technology. The quantum anomalous Hall effect provides spin-polarized dissipation-free transport of electrons, while the quantum spin Hall effect in combination with superconductivity has been proposed as the basis for realizing decoherence-free quantum computing. We introduce a new strategy for realizing these effects, namely by hole and electron doping kagome lattice Mott insulators through, for instance, chemical substitution. As an example, we apply this new approach to the natural mineral herbertsmithite. We prove the feasibility of the proposed modifications by performing ab-initio density functional theory calculations and demonstrate the occurrence of the predicted effects using realistic models. Our results herald a new family of quantum anomalous Hall and quantum spin Hall insulators at affordable energy/temperature scales based on kagome lattices of transition metal ions. PMID:27185665

  2. Prospect of quantum anomalous Hall and quantum spin Hall effect in doped kagome lattice Mott insulators

    Science.gov (United States)

    Guterding, Daniel; Jeschke, Harald O.; Valentí, Roser

    2016-01-01

    Electronic states with non-trivial topology host a number of novel phenomena with potential for revolutionizing information technology. The quantum anomalous Hall effect provides spin-polarized dissipation-free transport of electrons, while the quantum spin Hall effect in combination with superconductivity has been proposed as the basis for realizing decoherence-free quantum computing. We introduce a new strategy for realizing these effects, namely by hole and electron doping kagome lattice Mott insulators through, for instance, chemical substitution. As an example, we apply this new approach to the natural mineral herbertsmithite. We prove the feasibility of the proposed modifications by performing ab-initio density functional theory calculations and demonstrate the occurrence of the predicted effects using realistic models. Our results herald a new family of quantum anomalous Hall and quantum spin Hall insulators at affordable energy/temperature scales based on kagome lattices of transition metal ions. PMID:27185665

  3. Prospect of quantum anomalous Hall and quantum spin Hall effect in doped kagome lattice Mott insulators

    Science.gov (United States)

    Guterding, Daniel; Jeschke, Harald O.; Valentí, Roser

    2016-05-01

    Electronic states with non-trivial topology host a number of novel phenomena with potential for revolutionizing information technology. The quantum anomalous Hall effect provides spin-polarized dissipation-free transport of electrons, while the quantum spin Hall effect in combination with superconductivity has been proposed as the basis for realizing decoherence-free quantum computing. We introduce a new strategy for realizing these effects, namely by hole and electron doping kagome lattice Mott insulators through, for instance, chemical substitution. As an example, we apply this new approach to the natural mineral herbertsmithite. We prove the feasibility of the proposed modifications by performing ab-initio density functional theory calculations and demonstrate the occurrence of the predicted effects using realistic models. Our results herald a new family of quantum anomalous Hall and quantum spin Hall insulators at affordable energy/temperature scales based on kagome lattices of transition metal ions.

  4. Anomalous Effects of Driving Field Linewidth on a One-Atom Dressed-State Laser

    Institute of Scientific and Technical Information of China (English)

    YANG Jin-Jin; Hu Xiang-Ming

    2007-01-01

    We examine the effects of driving Geld linewidth on a one-atom dressed state laser. Unexpectedly, the linewidth leads to anomalous effects on the cavity Geld. The mean photon number of the cavity Geld is raised or the normalized variance is reduced to a certain degree as the linewidth increases for an appropriate range of parameters. The responsible mechanism is attributed to the fluctuation-induced modification of the electromagnetic reservoir where the atom stays.

  5. Anomalous resistance overshoot in the integer quantum Hall effect.

    Science.gov (United States)

    Kendirlik, E M; Sirt, S; Kalkan, S B; Dietsche, W; Wegscheider, W; Ludwig, S; Siddiki, A

    2013-01-01

    In this work we report on experiments performed on smooth edge-narrow Hall bars. The magneto-transport properties of intermediate mobility two-dimensional electron systems are investigated and analyzed within the screening theory of the integer quantized Hall effect. We observe a non-monotonic increase of Hall resistance at the low magnetic field ends of the quantized plateaus, known as the overshoot effect. Unexpectedly, for Hall bars that are defined by shallow chemical etching the overshoot effect becomes more pronounced at elevated temperatures. We observe the overshoot effect at odd and even integer plateaus, which favor a spin independent explanation, in contrast to discussion in the literature. In a second set of the experiments, we investigate the overshoot effect in gate defined Hall bar and explicitly show that the amplitude of the overshoot effect can be directly controlled by gate voltages. We offer a comprehensive explanation based on scattering between evanescent incompressible channels.

  6. Skin Firming, Skin Smoothing, Skin Blemishes Elimination and Anti-aging Effects of Increased Protein Intake in the Form of Voandzeia hypogeal Seed Meal

    Directory of Open Access Journals (Sweden)

    Utoh-Nedosa U. Anastasia

    2011-01-01

    Full Text Available Studies on the effect of excess calorie intake on the human body showed that it resulted in accumulation of excess body fat; the darkening of the skin colour and the development of a bumpy skin. Problem statement: The present study investigated the effects of increased protein intake on the human skin and on body fat. The skin firming, skin smoothing and skin colour lightening effects of Vernonia amygdalina leaf extract has already been established. The anti-obesity, body calming and anti-aging effects of VA leaf extract have also been established. Approach: The effects of increased protein intake (in the form of eating of 100 gm Voandzeia hypogeal seed paste meal two times daily, was tested on the skin, anti-obesity and anti-aging effects of VA leaf extract. The study was done for 10 days. Results: The results of the study showed that Voandzeia subterranean (hypogea cooked potentiated the skin tightening, skin smoothing, skin colour lightening and the anti-obesity/anti-aging effects of VA. Leaf extract. These results show that increased Voandezia hypogeal seed paste meal [increased protein intake has skin tightening/clearing/lightening/smoothing and anti-obesity/anti-aging effects]. They also show that cooked Voandzeia hypogeal seed paste meal has a potentiating effect on the skin and body effects of VA leaf extract. Conclusion: From the findings of this study the author to concludes that increased protein intake potentiated the skin firming/skin smoothing/skin colour lightening; body calming; anti-obesity and anti-aging effects of Vernonia amygdalina leaf extract. The study also concludes that Voandzeia hypogeal seed meal has skin firming/skin smoothing/skin colour lightening (clearing; body calming; anti-obesity and anti-aging effects.

  7. Nonadiabatic Effects in Ultracold Molecules via Anomalous Linear and Quadratic Zeeman Shifts

    OpenAIRE

    McGuyer, B. H.; Osborn, C. B.; McDonald, M.; Reinaudi, G.; Skomorowski, W.; Moszynski, R.; Zelevinsky, T.

    2013-01-01

    Anomalously large linear and quadratic Zeeman shifts are measured for weakly bound ultracold $^{88}$Sr$_2$ molecules near the intercombination-line asymptote. Nonadiabatic Coriolis coupling and the nature of long-range molecular potentials explain how this effect arises and scales roughly cubically with the size of the molecule. The linear shifts yield nonadiabatic mixing angles of the molecular states. The quadratic shifts are sensitive to nearby opposite $f$-parity states and exhibit fourth...

  8. 3d Transition Metal Adsorption Induced Vally-polarized Anomalous Hall Effect in Germanene

    OpenAIRE

    Zhou, P; Sun, L. Z.

    2015-01-01

    Based on DFT+U and Berry curvature calculations, we study the electronic structures and topological properties of 3d transition metal (TM) atom (from Ti to Co) adsorbed germanene (TM-germanene). We find that valley-polarized anomalous hall effect (VAHE) can be realized in germanene by adsorbing Cr, Mn, or Co atom on its surface. A finite valley hall voltage can be easily detected in its nanoribbon, which is important for valleytronics devices. Moreover, different valley-polarized current and ...

  9. Critical Review of Theoretical Models for Anomalous Effects (Cold Fusion) in Deuterated Metals

    OpenAIRE

    Chechin, V. A.; Tsarev, V. A.; Rabinowitz, M; Kim, Y. E.

    2003-01-01

    We briefly summarize the reported anomalous effects in deuterated metals at ambient temperature, commonly known as "Cold Fusion" (CF), with an emphasis on important experiments as well as the theoretical basis for the opposition to interpreting them as cold fusion. Then we critically examine more than 25 theoretical models for CF, including unusual nuclear and exotic chemical hypotheses. We conclude that they do not explain the data.

  10. Critical Review of Theoretical Models for Anomalous Effects (Cold Fusion) in Deuterated Metals

    CERN Document Server

    Chechin, V A; Rabinowitz, M; Kim, Y E

    1994-01-01

    We briefly summarize the reported anomalous effects in deuterated metals at ambient temperature, commonly known as "Cold Fusion" (CF), with an emphasis on important experiments as well as the theoretical basis for the opposition to interpreting them as cold fusion. Then we critically examine more than 25 theoretical models for CF, including unusual nuclear and exotic chemical hypotheses. We conclude that they do not explain the data.

  11. Semiclassical origin of anomalous shell effect for tetrahedral deformation in radial power-law potential model

    CERN Document Server

    Arita, Ken-ichiro

    2014-01-01

    Shell structures in single-particle energy spectra are investigated against regular tetrahedral type deformation using radial power-law potential model. Employing a natural way of shape parametrization which interpolate sphere and regular tetrahedron, we find prominent shell effects at rather large tetrahedral deformations, which bring about shell energies much larger than the cases of spherical and quadrupole type shapes. We discuss the semiclassical origin of these anomalous shell structures using periodic orbit theory.

  12. Revisiting the Anomalous rf Field Penetration into a Warm Plasma

    International Nuclear Information System (INIS)

    Radio-frequency [rf] waves do not penetrate into a plasma and are damped within it. The electric field of the wave and plasma current are concentrated near the plasma boundary in a skin layer. Electrons can transport the plasma current away from the skin layer due to their thermal motion. As a result, the width of the skin layer increases when electron temperature effects are taken into account. This phenomenon is called anomalous skin effect. The anomalous penetration of the rf electric field occurs not only for transversely propagating to the plasma boundary wave (inductively coupled plasmas) but also for the wave propagating along the plasma boundary (capacitively coupled plasmas). Such anomalous penetration of the rf field modifies the structure of the capacitive sheath. Recent advances in the nonlinear, non-local theory of the capacitive sheath are reported. It is shown that separating the electric field profile into exponential and non-exponential parts yields an efficient qualitative and quantitative description of the anomalous skin effect in both inductively and capacitively coupled plasma

  13. Evidence for Anomalous Effects on the Current Evolution in Tokamak Operating Scenarios

    Energy Technology Data Exchange (ETDEWEB)

    Casper, T; Jayakumar, R; Allen, S; Holcomb, C; Makowski, M; Pearlstein, L; Berk, H; Greenfield, C; Luce, T; Petty, C; Politzer, P; Wade, M; Murakami, M; Kessel, C

    2006-10-03

    Alternatives to the usual picture of advanced tokamak (AT) discharges are those that form when anomalous effects alter the plasma current and pressure profiles and those that achieve stationary characteristics through mechanisms so that a measure of desired AT features is maintained without external current-profile control. Regimes exhibiting these characteristics are those where the safety factor (q) evolves to a stationary profile with the on-axis and minimum q {approx} 1 and those with a deeply hollow current channel and high values of q. Operating scenarios with high fusion performance at low current and where the inductively driven current density achieves a stationary configuration with either small or non-existing sawteeth may enhance the neutron fluence per pulse on ITER and future burning plasmas. Hollow current profile discharges exhibit high confinement and a strong ''box-like'' internal transport barrier (ITB). We present results providing evidence for current profile formation and evolution exhibiting features consistent with anomalous effects or with self-organizing mechanisms. Determination of the underlying physical processes leading to these anomalous effects is important for scaling of current experiments for application in future burning plasmas.

  14. Giant Anomalous Hall Effect in the Chiral Antiferromagnet Mn3Ge

    Science.gov (United States)

    Kiyohara, Naoki; Tomita, Takahiro; Nakatsuji, Satoru

    2016-06-01

    The external field control of antiferromagnetism is a significant subject both for basic science and technological applications. As a useful macroscopic response to detect magnetic states, the anomalous Hall effect (AHE) is known for ferromagnets, but it has never been observed in antiferromagnets until the recent discovery in Mn3Sn . Here we report another example of the AHE in a related antiferromagnet, namely, in the hexagonal chiral antiferromagnet Mn3Ge . Our single-crystal study reveals that Mn3Ge exhibits a giant anomalous Hall conductivity |σx z|˜60 Ω-1 cm-1 at room temperature and approximately 380 Ω-1 cm-1 at 5 K in zero field, reaching nearly half of the value expected for the quantum Hall effect per atomic layer with Chern number of unity. Our detailed analyses on the anisotropic Hall conductivity indicate that in comparison with the in-plane-field components |σx z| and |σz y|, which are very large and nearly comparable in size, we find |σy x| obtained in the field along the c axis to be much smaller. The anomalous Hall effect shows a sign reversal with the rotation of a small magnetic field less than 0.1 T. The soft response of the AHE to magnetic field should be useful for applications, for example, to develop switching and memory devices based on antiferromagnets.

  15. Anomalous effective action, Noether current, Virasoro algebra and Horizon entropy

    Energy Technology Data Exchange (ETDEWEB)

    Majhi, Bibhas Ranjan [IUCAA, Ganeshkhind, Pune University Campus, Post Bag 4, Pune (India); Hebrew University of Jerusalem, Racah Institute of Physics, Jerusalem (Israel); Chakraborty, Sumanta [IUCAA, Ganeshkhind, Pune University Campus, Post Bag 4, Pune (India)

    2014-05-15

    Several investigations show that in a very small length scale there exist corrections to the entropy of black hole horizon. Due to fluctuations of the background metric and the external fields the action incorporates corrections. In the low energy regime, the one-loop effective action in four dimensions leads to trace anomaly. We start from the Noether current corresponding to the Einstein-Hilbert plus the one-loop effective action to calculate the charge for the diffeomorphisms which preserve the Killing horizon structure. Then a bracket for the charges is calculated. We show that the Fourier modes of the bracket are exactly similar to the Virasoro algebra. Then using the Cardy formula the entropy is evaluated. Finally, the explicit terms of the entropy expression is calculated for a classical background. It turns out that the usual expression for the entropy; i.e. the Bekenstein-Hawking form, is not modified. (orig.)

  16. Anomalous Hall effect in epitaxial ferrimagnetic anti-perovskite Mn4-xDyxN films

    Science.gov (United States)

    Meng, M.; Wu, S. X.; Zhou, W. Q.; Ren, L. Z.; Wang, Y. J.; Wang, G. L.; Li, S. W.

    2015-08-01

    Anomalous Hall effect (AHE) has been studied for ferrimagnetic antiperovskite Mn4-xDyxN films grown by molecular-beam epitaxy. The introduction of Dy changes the AHE dramatically, even changes its sign, while the variations in magnetization are negligible. Two sign reversals of the AHE (negative-positive-negative) are ascribed to the variation of charge carriers as a result of Fermi surface reconstruction. We further demonstrate that the AHE current JAH is dissipationless (independent of the scattering rate), by confirming that anomalous Hall conductivity, σAH, is proportional to the carrier density n at 5 K. Our study may provide a route to further utilize antiperovskite manganese nitrides in spintronics.

  17. Anomalous piezoelectric effects, found in the laboratory and reconstructed by numerical simulation

    Directory of Open Access Journals (Sweden)

    K. P. Teisseyre

    2002-06-01

    Full Text Available Various rocks and minerals, which are not piezoelectric in the common sense, exhibit transient electric polarization in response to sudden changes in stress load. This anomalous piezoelectric effect differs from the regular, static piezoelectric response, in which electric charges appear as a result of crystal lattice deformation. The anomalous piezoelectricity is dynamic decaying in a few seconds or a few tens of seconds. However, in some materials different polarization properties are discovered. To explain certain aspects of the polarization signal increase and decay, some complicated mechanisms of electric charge generation and relaxation need to be assumed in their number ? concurrence of two or three relaxation processes. The hypothetical mechanisms are only mentioned, as the purpose of this work is to construct numerical models, behaving like the rocks investigated. Examples of experimental plots are shown together with the results of the numerical simulation of these experiments.

  18. Ab initio theory of the scattering-independent anomalous Hall effect.

    Science.gov (United States)

    Weischenberg, Jürgen; Freimuth, Frank; Sinova, Jairo; Blügel, Stefan; Mokrousov, Yuriy

    2011-09-01

    We report on first-principles calculations of the side-jump contribution to the anomalous Hall conductivity (AHC) directly from the electronic structure of a perfect crystal. We implemented our approach for a short-range scattering disorder model within the density functional theory and computed the full scattering-independent AHC in elemental bcc Fe, hcp Co, fcc Ni, and L1(0) FePd and FePt alloys. The full AHC thus calculated agrees systematically with experiment to a degree unattainable so far, correctly capturing the previously missing elements of side-jump contributions, hence paving the way to a truly predictive theory of the anomalous Hall effect and turning it from a characterization tool to a probing tool of multiband complex electronic band structures.

  19. Large anomalous Hall effect driven by a nonvanishing Berry curvature in the noncolinear antiferromagnet Mn3Ge.

    Science.gov (United States)

    Nayak, Ajaya K; Fischer, Julia Erika; Sun, Yan; Yan, Binghai; Karel, Julie; Komarek, Alexander C; Shekhar, Chandra; Kumar, Nitesh; Schnelle, Walter; Kübler, Jürgen; Felser, Claudia; Parkin, Stuart S P

    2016-04-01

    It is well established that the anomalous Hall effect displayed by a ferromagnet scales with its magnetization. Therefore, an antiferromagnet that has no net magnetization should exhibit no anomalous Hall effect. We show that the noncolinear triangular antiferromagnet Mn3Ge exhibits a large anomalous Hall effect comparable to that of ferromagnetic metals; the magnitude of the anomalous conductivity is ~500 (ohm·cm)(-1) at 2 K and ~50 (ohm·cm)(-1) at room temperature. The angular dependence of the anomalous Hall effect measurements confirms that the small residual in-plane magnetic moment has no role in the observed effect except to control the chirality of the spin triangular structure. Our theoretical calculations demonstrate that the large anomalous Hall effect in Mn3Ge originates from a nonvanishing Berry curvature that arises from the chiral spin structure, and that also results in a large spin Hall effect of 1100 (ħ/e) (ohm·cm)(-1), comparable to that of platinum. The present results pave the way toward the realization of room temperature antiferromagnetic spintronics and spin Hall effect-based data storage devices. PMID:27152355

  20. Large anomalous Hall effect driven by a nonvanishing Berry curvature in the noncolinear antiferromagnet Mn3Ge.

    Science.gov (United States)

    Nayak, Ajaya K; Fischer, Julia Erika; Sun, Yan; Yan, Binghai; Karel, Julie; Komarek, Alexander C; Shekhar, Chandra; Kumar, Nitesh; Schnelle, Walter; Kübler, Jürgen; Felser, Claudia; Parkin, Stuart S P

    2016-04-01

    It is well established that the anomalous Hall effect displayed by a ferromagnet scales with its magnetization. Therefore, an antiferromagnet that has no net magnetization should exhibit no anomalous Hall effect. We show that the noncolinear triangular antiferromagnet Mn3Ge exhibits a large anomalous Hall effect comparable to that of ferromagnetic metals; the magnitude of the anomalous conductivity is ~500 (ohm·cm)(-1) at 2 K and ~50 (ohm·cm)(-1) at room temperature. The angular dependence of the anomalous Hall effect measurements confirms that the small residual in-plane magnetic moment has no role in the observed effect except to control the chirality of the spin triangular structure. Our theoretical calculations demonstrate that the large anomalous Hall effect in Mn3Ge originates from a nonvanishing Berry curvature that arises from the chiral spin structure, and that also results in a large spin Hall effect of 1100 (ħ/e) (ohm·cm)(-1), comparable to that of platinum. The present results pave the way toward the realization of room temperature antiferromagnetic spintronics and spin Hall effect-based data storage devices.

  1. Origin of enhanced anomalous Hall effect in ultrathin Pt/permalloy bilayers

    Directory of Open Access Journals (Sweden)

    Y. Q. Zhang

    2016-02-01

    Full Text Available There are two mechanisms which could enhance spin-dependent scattering in a low dimensional Pt/Ferromagnetic metal structure. One is magnetic proximity effect. The other is spin orbit coupling proximity effect which was suggested recently. This work demonstrates that, through a series of experiments on anomalous Hall effect, the spin orbit coupling proximity effect dominates the enhancement in very thin Pt/Permalloy bilayers. It may help to find a way to optimize magnetic transport property of spintronics devices in which the spin orbit coupling is deeply involved.

  2. Quantum Anomalous Hall Effect in Hg_1-yMn_yTe Quantum Wells

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Chao-Xing; /Tsinghua U., Beijing /Stanford U., Phys. Dept.; Qi, Xiao-Liang; /Stanford U., Phys. Dept.; Dai, Xi; Fang, Zhong; /Beijing, Inst. Phys.; Zhang, Shou-Cheng; /Stanford U., Phys. Dept.

    2010-03-19

    The quantum Hall effect is usually observed when the two-dimensional electron gas is subjected to an external magnetic field, so that their quantum states form Landau levels. In this work we predict that a new phenomenon, the quantum anomalous Hall effect, can be realized in Hg{sub 1-y}Mn{sub y}Te quantum wells, without the external magnetic field and the associated Landau levels. This effect arises purely from the spin polarization of the Mn atoms, and the quantized Hall conductance is predicted for a range of quantum well thickness and the concentration of the Mn atoms. This effect enables dissipationless charge current in spintronics devices.

  3. Skin moisturizing effects of panthenol-based formulations.

    Science.gov (United States)

    Camargo, Flávio B; Gaspar, Lorena R; Maia Campos, Patrícia M B G

    2011-01-01

    This study aims to evaluate the skin moisturizing efficacy of formulations containing different concentrations of panthenol. Formulations supplemented with or without 0.5%, 1.0%, or 5.0% panthenol were applied daily to the forearms of healthy subjects. Skin conditions in terms of moisture and transepidermal water loss (TEWL) were analyzed before and after 15- and 30-day periods of application. The formulations were also applied after skin washing with sodium laureth sulphate (SLES) to evaluate the immediate effects on TEWL and skin moisture. Panthenol-containing formulations (1.0% and 5.0%) produced significant decreases in TEWL after 30-day applications. In skin washed with SLES, significant reduction of TEWL was evident two hours after application of formulations loaded with panthenol when compared with control and vehicle. It is concluded that skin integrity is maintained by the improved protective effect of 1.0% panthenol added to the formulation. PMID:21982351

  4. Quantum Anomalous Hall Effect in Hg$_{1-y}$Mn$_{y}$Te Quantum Wells

    OpenAIRE

    Liu, Chao-Xing; Qi, Xiao-Liang; Dai, Xi; Fang, Zhong; Zhang, Shou-Cheng

    2008-01-01

    The quantum Hall effect is usually observed when the two-dimensional electron gas is subjected to an external magnetic field, so that their quantum states form Landau levels. In this work we predict that a new phenomenon, the quantum anomalous Hall effect, can be realized in Hg$_{1-y}$Mn$_{y}$Te quantum wells, without the external magnetic field and the associated Landau levels. This effect arises purely from the spin polarization of the $Mn$ atoms, and the quantized Hall conductance is predi...

  5. Anomalous coupling, top-mass and parton-shower effects in W + W - production

    Science.gov (United States)

    Bellm, J.; Gieseke, S.; Greiner, N.; Heinrich, G.; Plätzer, S.; Reuschle, C.; von Soden-Fraunhofen, J. F.

    2016-05-01

    We calculate the process ppto {W}+{W}-to {e}+{ν}_e{μ}-{overline{ν}}_{μ } at NLO QCD, including also effective field theory (EFT) operators mediating the ggW + W - interaction, which first occur at dimension eight. We further combine the NLO and EFT matrix elements produced by G oS am with the H erwig7/M atchbox framework, which offers the possibility to study the impact of a parton shower. We assess the effects of the anomalous couplings by comparing them to top-mass effects as well as uncertainties related to variations of the renormalisation, factorisation and hard shower scales.

  6. Ice Ih anomalies: Thermal contraction, anomalous volume isotope effect, and pressure-induced amorphization.

    Science.gov (United States)

    Salim, Michael A; Willow, Soohaeng Yoo; Hirata, So

    2016-05-28

    Ice Ih displays several anomalous thermodynamic properties such as thermal contraction at low temperatures, an anomalous volume isotope effect (VIE) rendering the volume of D2O ice greater than that of H2O ice, and a pressure-induced transition to the high-density amorphous (HDA) phase. Furthermore, the anomalous VIE increases with temperature, despite its quantum-mechanical origin. Here, embedded-fragment ab initio second-order many-body perturbation (MP2) theory in the quasiharmonic approximation (QHA) is applied to the Gibbs energy of an infinite, proton-disordered crystal of ice Ih at wide ranges of temperatures and pressures. The quantum effect of nuclei moving in anharmonic potentials is taken into account from first principles without any empirical or nonsystematic approximation to either the electronic or vibrational Hamiltonian. MP2 predicts quantitatively correctly the thermal contraction at low temperatures, which is confirmed to originate from the volume-contracting hydrogen-bond bending modes (acoustic phonons). It qualitatively reproduces (but underestimates) the thermal expansion at higher temperatures, caused by the volume-expanding hydrogen-bond stretching (and to a lesser extent librational) modes. The anomalous VIE is found to be the result of subtle cancellations among closely competing isotope effects on volume from all modes. Consequently, even ab initio MP2 with the aug-cc-pVDZ and aug-cc-pVTZ basis sets has difficulty reproducing this anomaly, yielding qualitatively varied predictions of the sign of the VIE depending on such computational details as the choice of the embedding field. However, the temperature growth of the anomalous VIE is reproduced robustly and is ascribed to the librational modes. These solid-state MP2 calculations, as well as MP2 Born-Oppenheimer molecular dynamics, find a volume collapse and a loss of symmetry and long-range order in ice Ih upon pressure loading of 2.35 GPa or higher. Concomitantly, rapid softening of

  7. Ice Ih anomalies: Thermal contraction, anomalous volume isotope effect, and pressure-induced amorphization

    Science.gov (United States)

    Salim, Michael A.; Willow, Soohaeng Yoo; Hirata, So

    2016-05-01

    Ice Ih displays several anomalous thermodynamic properties such as thermal contraction at low temperatures, an anomalous volume isotope effect (VIE) rendering the volume of D2O ice greater than that of H2O ice, and a pressure-induced transition to the high-density amorphous (HDA) phase. Furthermore, the anomalous VIE increases with temperature, despite its quantum-mechanical origin. Here, embedded-fragment ab initio second-order many-body perturbation (MP2) theory in the quasiharmonic approximation (QHA) is applied to the Gibbs energy of an infinite, proton-disordered crystal of ice Ih at wide ranges of temperatures and pressures. The quantum effect of nuclei moving in anharmonic potentials is taken into account from first principles without any empirical or nonsystematic approximation to either the electronic or vibrational Hamiltonian. MP2 predicts quantitatively correctly the thermal contraction at low temperatures, which is confirmed to originate from the volume-contracting hydrogen-bond bending modes (acoustic phonons). It qualitatively reproduces (but underestimates) the thermal expansion at higher temperatures, caused by the volume-expanding hydrogen-bond stretching (and to a lesser extent librational) modes. The anomalous VIE is found to be the result of subtle cancellations among closely competing isotope effects on volume from all modes. Consequently, even ab initio MP2 with the aug-cc-pVDZ and aug-cc-pVTZ basis sets has difficulty reproducing this anomaly, yielding qualitatively varied predictions of the sign of the VIE depending on such computational details as the choice of the embedding field. However, the temperature growth of the anomalous VIE is reproduced robustly and is ascribed to the librational modes. These solid-state MP2 calculations, as well as MP2 Born-Oppenheimer molecular dynamics, find a volume collapse and a loss of symmetry and long-range order in ice Ih upon pressure loading of 2.35 GPa or higher. Concomitantly, rapid softening of

  8. The framing effect and skin conductance responses

    Directory of Open Access Journals (Sweden)

    Patrick eRing

    2015-08-01

    Full Text Available Individuals often rely on simple heuristics when they face complex choice situations under uncertainty. Traditionally, it has been proposed that cognitive processes are the main driver to evaluate different choice options and finally to reach a decision. Growing evidence, however, highlights a strong interrelation between judgment and decision-making (JDM on the one hand, and emotional processes on the other hand. This also seems to apply to judgmental heuristics, i.e. decision-processes that are typically considered to be fast and intuitive. In this study, participants are exposed to different probabilities of receiving an unpleasant electric shock. Information about electric shock probabilities is either positively or negatively framed. Integrated skin conductance responses (ISCRs while waiting for electric shock realization are used as an indicator for participants' emotional arousal. This measure is compared to objective probabilities. I find evidence for a relation between emotional body reactions measured by ISCRs and the framing effect. Under negative frames, participants show significantly higher ISCRs while waiting for an electric shock to be delivered than under positive frames. This result might contribute to a better understanding of the psychological processes underlying JDM. Further studies are necessary to reveal the causality underlying this finding, i.e. whether emotional processes influence JDM or vice versa.

  9. Anomalous Josephson Effect in Junctions with Rashba Spin-Orbit Coupling

    Science.gov (United States)

    Nesterov, Konstantin; Houzet, Manuel; Meyer, Julia

    2015-03-01

    We study two-dimensional double-barrier SINIS Josephson junctions in which the inversion symmetry in the normal part is broken by Rashba spin-orbit coupling. In the presence of a suitably oriented Zeeman field in the normal part, the system displays the anomalous Josephson effect: the current is nonzero even at zero phase difference between two superconductors. We investigate this effect by means of the Ginzburg-Landau formalism and microscopic Green's functions approach in the clean limit. This work was supported in part by the Grants No. ANR-12-BS04-0016-03 and an EU-FP7 Marie Curie IRG.

  10. Inverted effective SUSY with combined Z' and gravity mediation, and muon anomalous magnetic moment

    OpenAIRE

    Kim, Jihn E.

    2012-01-01

    Effective supersymmetry(SUSY) where stop is the lightest squark may run into a two-loop tachyonic problem in some Z' mediation models. In addition, a large A term or/and a large stop mass are needed to have about a 126 GeV Higgs boson with three families of quarks and leptons. Thus, we suggest an inverted effective SUSY(IeffSUSY) where stop mass is larger compared to those of the first two families. In this case, it is possible to have a significant correction to the anomalous magnetic moment...

  11. Relation between the structure and catalytic activity for automotive emissions. Use of x-ray anomalous dispersion effect

    CERN Document Server

    Mizuki, J; Tanaka, H

    2003-01-01

    The employment of the X-ray anomalous dispersion effect allows us to detect the change in structure of catalytic converters with the environment exposed. Here we show that palladium atoms in a perovskite crystal move into and out of the crystal by anomalous X-ray diffraction and absorption techniques. This movement of the precious metal plays an important role to keep the catalytic activity long-lived. (author)

  12. Effect of glove occlusion on the skin barrier

    DEFF Research Database (Denmark)

    Tiedemann, Daniel; Clausen, Maja Lisa; John, Swen Malthe;

    2016-01-01

    of this study is to review the literature on the effects of glove occlusion on skin barrier function. The PubMed database was searched up to 1 February 2015 for articles on the association between glove occlusion and skin barrier function, including human studies only and in English. Only experimental studies...

  13. Effect of anomalous vertex on decay-lepton distributions in + -→ t\\overline{t}$ and CP-violating asymmetries

    Indian Academy of Sciences (India)

    Saurabh D Rindani

    2000-06-01

    We obtain analytic expressions for the energy and polar-angle double differential distributions of a secondary lepton +(-) arising from the decay of ($\\overline{t}$) in + - → $t\\overline{t}$ with an anomalous decay vertex. We also obtain analytic expressions for the various differential cross-sections with the lepton energy integrat ed over. In this case, we find that the angular distributions of the secondary lepton do not depend on the anomalous coupling in the decay, regardless of possible anomalous couplings occurring in the production amplitude for + - → $t\\overline{t}$. Our study includes the effect of longitudinal - and + beam polarization. We also study the lepton energy and beam polarization dependence of certain CP-violating lepton angular asymmetries arising from an anomalous decay vertex and compare them with the asymmetries arising due to CP-violation in the production process due to the top electric or weak dipole moment.

  14. Stacking order dependence of inverse spin Hall effect and anomalous Hall effect in spin pumping experiments

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sang-Il; Seo, Min-Su; Park, Seung-Young, E-mail: parksy@kbsi.re.kr [Division of Materials Science, Korea Basic Science Institute, Daejeon 305-806 (Korea, Republic of); Kim, Dong-Jun; Park, Byong-Guk [Department of Materials Science and Engineering, KAIST, Daejeon 305-701 (Korea, Republic of)

    2015-05-07

    The dependence of the measured DC voltage on the non-magnetic material (NM) in NM/CoFeB and CoFeB/NM bilayers is studied under ferromagnetic resonance conditions in a TE{sub 011} resonant cavity. The directional change of the inverse spin Hall effect (ISHE) voltage V{sub ISHE} for the stacking order of the bilayer can separate the pure V{sub ISHE} and the anomalous Hall effect (AHE) voltage V{sub AHE} utilizing the method of addition and subtraction. The Ta and Ti NMs show a broad deviation of the spin Hall angle θ{sub ISH}, which originates from the AHE in accordance with the high resistivity of NMs. However, the Pt and Pd NMs show that the kinds of NMs with low resistivity are consistent with the previously reported θ{sub ISH} values. Therefore, the characteristics that NM should simultaneously satisfy to obtain a reasonable V{sub ISHE} value in bilayer systems are large θ{sub ISH} and low resistivity.

  15. From magnetically doped topological insulator to the quantum anomalous Hall effect

    Institute of Scientific and Technical Information of China (English)

    He Ke; Ma Xu-Cun; Chen Xi; Lü Li; Wang Ya-Yu; Xue Qi-Kun

    2013-01-01

    Quantum Hall effect (QHE),as a class of quantum phenomena that occur in macroscopic scale,is one of the most important topics in condensed matter physics.It has long been expected that QHE may occur without Landau levels so that neither extemal magnetic field nor high sample mobility is required for its study and application.Such a QHE free of Landau levels,can appear in topological insulators (TIs) with ferromagnetism as the quantized version of the anomalous Hall effect,i.e.,quantum anomalous Hall (QAH) effect.Here we review our recent work on experimental realization of the QAH effect in magnetically doped TIs.With molecular beam epitaxy,we prepare thin films of Cr-doped (Bi,Sb)2Te3 TIs with wellcontrolled chemical potential and long-range ferromagnetic order that can survive the insulating phase.In such thin films,we eventually observed the quantization of the Hall resistance at h/e2 at zero field,accompanied by a considerable drop in the longitudinal resistance.Under a strong magnetic field,the longitudinal resistance vanishes,whereas the Hall resistance remains at the quantized value.The realization of the QAH effect provides a foundation for many other novel quantum phenomena predicted in TIs,and opens a route to practical applications of quantum Hall physics in low-power-consumption electronics.

  16. FALLOUT RADIATION: EFFECTS ON THE SKIN

    Energy Technology Data Exchange (ETDEWEB)

    Conard, R. A.; Cronkite, E. P.; Bond, V. P.

    1963-02-06

    Until recently it has been generally assumed that injury to the skin from ionizing radiation was not a serious hazard associated with the detonation of nuclear dcvices. However, in 1954 the importance of this hazard became apparent when widespread lesions of the skin developed in a large group of people accidentally exposed to fallout radiation in the Marshall Islands following the experimental detonation of a large nuclear device. The accident in the Marshall Islands affords an example of large numbers of lesions of the skin in human beings from the fallout. Studies have been documented and will be referred to frequently in this chapter. The possibility of such accidents must be considered seriously in view of the increasingly widespread use of radioisotopes.

  17. CONVECTIVE DRYING OF CHERRY TOMATO: STUDY OF SKIN EFFECT

    Directory of Open Access Journals (Sweden)

    R. KHAMA

    2016-03-01

    Full Text Available A whole single cherry tomato was dried in a forced convective micro-dryer. The experiments were carried out at constant air velocity and humidity and temperatures of 50, 60, 70 °C. In order to study the effect of the skin, two sets of experiments were performed using a tomato with and without skin (easily removed. Shorter drying times were obtained when increasing drying temperatures as well as when removing sample skin. X-ray microtomography, a non-destructive 3D imaging technique was used to follow shrinkage of the samples. This phenomenon was introduced in the modelling part of this study. Analytical solutions of the Fick’law were used to determine the diffusion coefficient at the three temperatures studied, and then the activation energy was obtained through fitting the Arrhenius equation. The skin effect was clearly evidenced by showing that the mass transfer parameter values of an original tomato with skin were largely smaller than the one without skin. Indeed, the moisture effective diffusivity ranged from 2.56×10-11 to 7.67×10-11 m2·s-1 with activation energy of 50430 J·mol-1 for tomato with skin an ranged from 4.59×10-10 m2·s-1 to 6.73×10-10 m2·s-1 with activation energy of 17640 J.mol-1 for tomato without skin.

  18. 3d Transition Metal Adsorption Induced the valley-polarized Anomalous Hall Effect in Germanene

    Science.gov (United States)

    Zhou, P.; Sun, L. Z.

    2016-06-01

    Based on DFT + U and Berry curvature calculations, we study the electronic structures and topological properties of 3d transition metal (TM) atom (from Ti to Co) adsorbed germanene (TM-germanene). We find that valley-polarized anomalous Hall effect (VAHE) can be realized in germanene by adsorbing Cr, Mn, or Co atoms on its surface. A finite valley Hall voltage can be easily detected in their nanoribbon, which is important for valleytronics devices. Moreover, different valley-polarized current and even reversible valley Hall voltage can be archived by shifting the Fermi energy of the systems. Such versatile features of the systems show potential in next generation electronics devices.

  19. Experimental research of electron beam instability on the Doppler anomalous effect

    International Nuclear Information System (INIS)

    Beam instability caused by the Doppler anomalous effect (DAE) at electron beam interaction with the decelerating electrodynamic system (a resonator with a single-thread spiral and a resonator with a space-periodic structure) placed in the external homogeneous field are studied experimentally to investigate main mechanisms of instability of charged particle beams. Such general properties of DAE as resonance conditions for instability excitation, increase of the internal energy of oscillators (Larmor and Langmuir) during radiation, energy ratios for slow cyclotron and plasma waves of an electron beam are studied. Good agreement between experimental and theoretical results is obtained

  20. Anomalous transport model study of chiral magnetic effects in heavy ion collisions

    CERN Document Server

    Sun, Yifeng; Li, Feng

    2016-01-01

    Using an anomalous transport model for massless quarks, we study the effect of magnetic field on the elliptic flows of quarks and antiquarks in relativistic heavy ion collisions. With initial conditions from a blast wave model and assuming that the strong magnetic field produced in non-central heavy ion collisions can last for a sufficiently long time, we obtain an appreciable electric quadrupole moment in the transverse plane of a heavy ion collision, which subsequently leads to a splitting between the elliptic flows of quarks and antiquarks as expected from the chiral magnetic wave formed in the produced QGP and observed in experiments at the Relativistic Heavy Ion Collider (RHIC).

  1. Nonadiabatic effects in ultracold molecules via anomalous linear and quadratic Zeeman shifts.

    Science.gov (United States)

    McGuyer, B H; Osborn, C B; McDonald, M; Reinaudi, G; Skomorowski, W; Moszynski, R; Zelevinsky, T

    2013-12-13

    Anomalously large linear and quadratic Zeeman shifts are measured for weakly bound ultracold 88Sr2 molecules near the intercombination-line asymptote. Nonadiabatic Coriolis coupling and the nature of long-range molecular potentials explain how this effect arises and scales roughly cubically with the size of the molecule. The linear shifts yield nonadiabatic mixing angles of the molecular states. The quadratic shifts are sensitive to nearby opposite f-parity states and exhibit fourth-order corrections, providing a stringent test of a state-of-the-art ab initio model. PMID:24483652

  2. Measurement of Nonadiabatic Effects in Ultracold Molecules via Anomalous Linear and Quadratic Zeeman Shifts

    CERN Document Server

    McGuyer, B H; McDonald, M; Reinaudi, G; Skomorowski, W; Moszynski, R; Zelevinsky, T

    2013-01-01

    Anomalously large linear and quadratic Zeeman shifts are measured for weakly bound ultracold $^{88}$Sr$_2$ molecules near the intercombination line asymptote. Nonadiabatic Coriolis coupling and the nature of long-range molecular potentials explain how this effect arises and scales roughly cubically with the size of the molecule. The linear shifts yield nonadiabatic mixing angles of the molecular states. The quadratic shifts are sensitive to fourth-order contributions and to nearby opposite $f$-parity states, and provide a stringent test of a state-of-the-art ab initio model.

  3. Anomalous Hall effect of heavy holes in Ⅲ-Ⅴ semiconductor quantum wells

    Institute of Scientific and Technical Information of China (English)

    Wang Zhi-Gang; Zhang Ping

    2007-01-01

    The anomalous Hall effect of heavy holes in semiconductor quantum wells is studied in the intrinsic transport regime, where the Berry curvature governs the Hall current properties. Based on the first-order perturbation of wave function the expression of the Hall conductivity the same as that from the semiclassical equation of motion of the Bloch particles is derived. The dependence of Hall conductivity on the system parameters is shown. The amplitude of Hall conductivity is found to be balanced by a competition between the Zeeman splitting and the spin-orbit splitting.

  4. Evidence of local effects in anomalous refraction and focusing properties of dodecagonal photonic quasicrystals

    CERN Document Server

    Di Gennaro, Emiliano; Savo, Salvatore; Andreone, Antonello; Morello, Davide; Galdi, Vincenzo; Castaldi, Giuseppe; Pierro, Vincenzo

    2008-01-01

    We present the key results from a comprehensive study of the refraction and focusing properties of a two-dimensional dodecagonal photonic ``quasicrystal'' (PQC), carried out via both full-wave numerical simulations and microwave measurements on a slab made of alumina rods inserted in a parallel-plate waveguide. We observe anomalous refraction and focusing in several frequency regions, confirming some recently published results. However, our interpretation, based on numerical and experimental evidence, differs substantially from the one in terms of ``effective negative refractive-index'' that was originally proposed. Instead, our study highlights the critical role played by short-range interactions associated with local order and symmetry.

  5. Global Constraints on Anomalous Triple Gauge Couplings in the Effective Field Theory Approach

    Science.gov (United States)

    Falkowski, Adam; González-Alonso, Martín; Greljo, Admir; Marzocca, David

    2016-01-01

    We present a combined analysis of LHC Higgs data (signal strengths) together with LEP-2 W W production measurements. To characterize possible deviations from the standard model (SM) predictions, we employ the framework of an effective field theory (EFT) where the SM is extended by higher-dimensional operators suppressed by the mass scale of new physics Λ . The analysis is performed consistently at the order Λ-2 in the EFT expansion keeping all the relevant operators. While the two data sets suffer from flat directions, together they impose stringent model-independent constraints on the anomalous triple gauge couplings.

  6. The giant anomalous Hall effect in the ferromagnet Fe3Sn2--a frustrated kagome metal.

    Science.gov (United States)

    Kida, T; Fenner, L A; Dee, A A; Terasaki, I; Hagiwara, M; Wills, A S

    2011-03-23

    The kagome-bilayer material Fe(3)Sn(2) has recently been shown to be an example of a rare class of magnet-a frustrated ferromagnetic metal. While the magnetism of Fe(3)Sn(2) appears to be relatively simple at high temperature, with localized moments parallel to the c-axis (T(C) = 640 K), upon cooling the competing exchange interactions and spin frustration become apparent as they cause the moments to become non-collinear and to rotate towards the kagome plane, forming firstly a canted ferromagnetic structure and then a re-entrant spin glass (T(f) approximately equal 80 K). In this work we show that Fe(3)Sn(2) possesses an unusual anomalous Hall effect. The saturated Hall resistivity of Fe(3)Sn(2) is 3.2 µΩ cm at 300 K, almost 20 times higher than that of typical itinerant ferromagnets such as Fe and Ni. The anomalous Hall coefficient R(s) is 6.7 × 10(-9) Ω cm G(-1) at 300 K, which is three orders of magnitude larger than that of pure Fe, and obeys an unconventional scaling with the longitudinal resistivity, ρ(xx), of R(s) is proportional to ρ(xx)(3.15). Such a relationship cannot be explained by either the conventional skew or side-jump mechanisms, indicating that the anomalous Hall effect in Fe(3)Sn(2) has an extraordinary origin that is presumed to be related to the underlying frustration of the magnetism. These findings demonstrate that frustrated ferromagnets, whether based on bulk materials or on artificial nanoscale structures, can provide new routes to room temperature spin-dependent electron transport properties suited to application in spintronics.

  7. Large anomalous Hall effect in Pt interfaced with perpendicular anisotropy ferrimagnetic insulator

    Science.gov (United States)

    Tang, Chi; Sellappan, Pathikumar; Liu, Yawen; Garay, Javier; Shi, Jing; Shines Team

    We demonstrate the strain induced perpendicular magnetic anisotropy (PMA) in a ferrimagnetic insulator (FMI), Tm3Fe5O12 (TIG) and the first observation of large anomalous Hall effect (AHE) in TIG/Pt bilayers. Atomically flat TIG films were deposited by a laser molecular beam epitaxy system on (111)-orientated substituted gadolinium gallium garnet substrates. The strength of PMA could be effectively tuned by controlling the oxygen pressure during deposition. Sharp squared anomalous Hall hysteresis loops were observed in bilayers of TIG/Pt over a range of thicknesses of Pt, with the maximum AHE conductivity reaching 1 S/cm at room temperature. The AHE vanishes when a 5 nm Cu layer was inserted between Pt and TIG, strongly indicating the proximity-induced ferromagnetism in Pt. The large AHE in the bilayer structures demonstrates a potential use of PMA-FMI related heterostructures in spintronics. This work was supported as part of the SHINES, an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science, Basic Energy Sciences under Award # SC0012670.

  8. Semiclassical wave packet study of anomalous isotope effect in ozone formation.

    Science.gov (United States)

    Vetoshkin, Evgeny; Babikov, Dmitri

    2007-10-21

    We applied the semiclassical initial value representation method to calculate energies, lifetimes, and wave functions of scattering resonances in a two-dimensional potential for O+O2 collision. Such scattering states represent the metastable O3* species and play a central role in the process of ozone formation. Autocorrelation functions for scattering states were computed and then analyzed using the Prony method, which permits one to extract accurate energies and widths of the resonances. We found that the results of the semiclassical wave packet propagation agree well with fully quantum results. The focus was on the 16O16O18O isotopomer and the anomalous isotope effect associated with formation of this molecule, either through the 16O16O+18O or the 16O+16O18O channels. An interesting correlation between the local vibration mode character of the metastable states and their lifetimes was observed and explained. New insight is obtained into the mechanism by which the long-lived resonances in the delta zero-point energy part of spectrum produce the anomalously large isotope effect.

  9. Effects of Neutron Skin Thickness in Peripheral Nuclear Reactions

    Institute of Scientific and Technical Information of China (English)

    FANG De-Qing; MA Yu-Gang; CAI Xiang-Zhou; TIAN Wen-Dong; WANG Hong-Wei

    2011-01-01

    Effects of neutron skin thickness in peripheral nuclear collisions are investigated using the statistical abrasion ablation (SAA) model. The reaction cross section, neutron (proton) removal cross section, one-neutron (proton) removal cross section as well as their ratios for nuclei with different neutron skin thickness are studied. It is demonstrated that there are good linear correlations between these observables and the neutron skin thickness for neutron-rich nuclei. The ratio between the (one-)neutron and proton removal cross section is found to be the most sensitive observable of neutron skin thickness. Analysis shows that the relative increase of this ratio could be used to determine the neutron skin size in neutron-rich nuclei.%Effects of neutron skin thickness in peripheral nuclear collisions are investigated using the statistical abrasion ablation (SAA ) model.The reaction cross section,neutron (proton) removal cross section,one-neutron (proton) removal cross section as well as their ratios for nuclei with different neutron skin thickness are studied.It is demonstrated that there are good linear correlations between these observables and the neutron skin thickness for neutron-rich nuclei.The ratio between the (one-)neutron and proton removal cross section is found to be the most sensitive observable of neutron skin thickness.Analysis shows that the relative increase of this ratio could be used to determine the neutron skin size in neutron-rich nuclei.Determining the size and shape of a nucleus is one of the most important subjects since the discovery of atomic nuclei.The rms radii of the neutron (rn) and proton (rp) density distributions are among the most prominent observables for this purpose.Studies for stable nuclei have shown that the nuclear radii are proportional to A1/3,with A being the nuclear mass number.Meanwhile,the density distributions of neutrons and protons in stable nuclei are very similar.

  10. Effects of Anomalous Tensor Couplings in BOs -(B-)Os Mixing

    Institute of Scientific and Technical Information of China (English)

    CHANG Qin; HAN Lin; YANG Ya-Dong

    2012-01-01

    Motivated by the recently observed anomalous large dimuon charge asymmetry in neutral B decays,we study the effects of the anomalous tensor couplings to pursue a possible solution.With the constraints from the observables φJ/(φ)(φ,f0)s,aSsl and ΔMs,the new physics parameter spaces are severely restricted.We find that the contributions induced by the color-singlet or the color-octet tensor operators are helpful to moderate the anomaly in BOs - (B-)Osmixing.Numerically,the observable aSsl could be enhanced by about two orders of magnitude by the contributionsof color-singlet or color-octet tensor operators with their respective nontrivial new weak phase φT1 =41° ± 35° orφs =-47° ± 33° and relevant strength parameters |gT1| =(2.89 ± 1.40) × 10-2 or |gT8| =(0.79 ± 0.34) × 10-2.However,due to the fact that the NP contributions are severely suppressed by the recent LHCb measurement for φJ/φ(φ,f0)s,our theoretical result of aSsl is still much smaller than the central value of the experimental data.

  11. Anomalous scaling in magnetohydrodynamic turbulence: Effects of anisotropy and compressibility in the kinematic approximation.

    Science.gov (United States)

    Antonov, N V; Kostenko, M M

    2015-11-01

    The field-theoretic renormalization group and the operator product expansion are applied to the model of passive vector (magnetic) field advected by a random turbulent velocity field. The latter is governed by the Navier-Stokes equation for compressible fluid, subject to external random force with the covariance ∝ δ(t-t')k(4-d-y), where d is the dimension of space and y is an arbitrary exponent. From physics viewpoints, the model describes magnetohydrodynamic turbulence in the so-called kinematic approximation, where the effects of the magnetic field on the dynamics of the fluid are neglected. The original stochastic problem is reformulated as a multiplicatively renormalizable field-theoretic model; the corresponding renormalization group equations possess an infrared attractive fixed point. It is shown that various correlation functions of the magnetic field and its powers demonstrate anomalous scaling behavior in the inertial-convective range already for small values of y. The corresponding anomalous exponents, identified with scaling (critical) dimensions of certain composite fields ("operators" in the quantum-field terminology), can be systematically calculated as series in y. The practical calculation is performed in the leading one-loop approximation, including exponents in anisotropic contributions. It should be emphasized that, in contrast to Gaussian ensembles with finite correlation time, the model and the perturbation theory presented here are manifestly Galilean covariant.

  12. Assessing the effects of timing irregularities on radio pulsars anomalous braking indices

    Science.gov (United States)

    Chukwude, A. E.; Chidi Odo, Finbarr

    2016-10-01

    We investigate the statistical effects of non-discrete timing irregularities on observed radio pulsar braking indices using correlations between the second derivative of the measured anomalous frequency (̈νobs) and some parameters that have been widely used to quantify pulsar timing fluctuations (the timing activity parameter (A), the amount of timing fluctuations absorbed by the cubic term (σR23) and a measure of pulsar rotational stability (σz)) in a large sample of 366 Jodrell Bank Observatory radio pulsars. The result demonstrates that anomalous braking indices are largely artifacts produced by aggregations of fluctuations that occur within or outside the pulsar system. For a subsample of 223 normal radio pulsars whose observed timing activity appeared consistent with instabilities in rotation of the underlying neutron stars (or timing noise) over timescales of ˜ 10 – 40 yr, |̈νobs| strongly correlates (with correlation coefficient |r| ˜ 0.80 – 0.90) with the pulsar timing activity parameters and spin-down properties. On the other hand, no meaningful correlations (r objects, whose timing activity appears significantly dominated by white noise fluctuations. The current result can be better understood if the timing noise in isolated pulsars originates from intrinsic spin-down processes of the underlying neutron stars, but white noise fluctuations largely arise from processes external to the pulsar system.

  13. Anomalous scaling in magnetohydrodynamic turbulence: Effects of anisotropy and compressibility in the kinematic approximation.

    Science.gov (United States)

    Antonov, N V; Kostenko, M M

    2015-11-01

    The field-theoretic renormalization group and the operator product expansion are applied to the model of passive vector (magnetic) field advected by a random turbulent velocity field. The latter is governed by the Navier-Stokes equation for compressible fluid, subject to external random force with the covariance ∝ δ(t-t')k(4-d-y), where d is the dimension of space and y is an arbitrary exponent. From physics viewpoints, the model describes magnetohydrodynamic turbulence in the so-called kinematic approximation, where the effects of the magnetic field on the dynamics of the fluid are neglected. The original stochastic problem is reformulated as a multiplicatively renormalizable field-theoretic model; the corresponding renormalization group equations possess an infrared attractive fixed point. It is shown that various correlation functions of the magnetic field and its powers demonstrate anomalous scaling behavior in the inertial-convective range already for small values of y. The corresponding anomalous exponents, identified with scaling (critical) dimensions of certain composite fields ("operators" in the quantum-field terminology), can be systematically calculated as series in y. The practical calculation is performed in the leading one-loop approximation, including exponents in anisotropic contributions. It should be emphasized that, in contrast to Gaussian ensembles with finite correlation time, the model and the perturbation theory presented here are manifestly Galilean covariant. PMID:26651785

  14. Skin.

    Science.gov (United States)

    Mancini, Anthony J

    2004-04-01

    Human skin provides a barrier between the host and the physical, chemical, and biological environment. It is also a potential portal of entry for hazardous or infectious agents and a potential target of environmental toxins. Cutaneous vulnerability may take on many forms in the embryo, infant, child, and adolescent. Teratogenic agents may occasionally target skin, as appreciated in the proposed association of the antithyroid medication methimazole, with the congenital malformation known as aplasia cutis congenita. Percutaneous absorption of topically applied substances and the potential for resultant drug toxicities are important considerations in the child. Many topical agents have been associated with systemic toxicity, including alcohol, hexachlorophene, iodine-containing compounds, eutectic mixture of local anesthetics, and lindane. Percutaneous toxicity is of greatest concern in the premature infant, in whom immaturity of the epidermal permeability barrier results in disproportionately increased absorption. Immature drug metabolism capabilities may further contribute to the increased risk in this population. Ultraviolet (UV) radiation exposure, which increases an individual's risk of cutaneous carcinogenesis, may be a particularly significant risk factor when it occurs during childhood. The "critical period hypothesis" suggests that UV exposure early in life increases the risk of eventual development of malignant melanoma. Other risk factors for malignant melanoma may include severe sunburns during childhood, intense intermittent UV exposure, and increased susceptibility of pediatric melanocytes to UV-induced DNA damage. Last, percutaneous exposure to environmental toxins and chemicals, such as insecticides and polychlorinated biphenyls, may differ between children and adults for several reasons, including behavioral patterns, anatomic and physiologic variations, and developmental differences of vital organs. PMID:15060207

  15. Scaling of Anomalous Hall Effects in Facing-Target Reactively Sputtered Fe4N Films

    KAUST Repository

    Zhang, Yan

    2015-05-13

    Anomalous Hall effect (AHE) in the reactively sputtered epitaxial and polycrystalline γ′-Fe4N films is investigated systematically. The Hall resistivity is positive in the entire temperature range. The magnetization, carrier density and grain boundaries scattering have a major impact on the AHE scaling law. The scaling exponent γ in the conventional scaling of is larger than 2 in both the epitaxial and polycrystalline γ′-Fe4N films. Although γ>2 has been found in heterogeneous systems due to the effects of the surface and interface scattering on AHE, γ>2 is not expected in homogenous epitaxial systems. We demonstrated that γ>2 results from residual resistivity (ρxx0) in γ′-Fe4N films. Furthermore, the side-jump and intrinsic mechanisms are dominant in both epitaxial and polycrystalline samples according to the proper scaling relation.

  16. Structure investigation of metal ions clustering in dehydrated gel using x-ray anomalous dispersion effect

    CERN Document Server

    Soejima, Y; Sugiyama, M; Annaka, M; Nakamura, A; Hiramatsu, N; Hara, K

    2003-01-01

    The structure of copper ion clusters in dehydrated N-isopropylacrylamide/sodium acrylate (NIPA/SA) gel has been studied by means of small angle X-ray scattering (SAXS) method. In order to distinguish the intensity scattered by Cu ions, the X-ray anomalous dispersion effect around the Cu K absorption edge has been coupled with SAXS. It is found that the dispersion effect dependent on the incident X-ray energy is remarkable only at the momentum transfer q = 0.031 A sup - sup 1 , where a SAXS peak is observed. The results indicate that copper ions form clusters in the dehydrated gel, and that the mean size of clusters is the same as that of SA clusters produced by microphase separation. It is therefore naturally presumed that copper ions are adsorbed into the SA molecules. On the basis of the presumption, a mechanism is proposed for microphase-separation and clustering of Cu ions.

  17. Effect of Surfactant Mixtures on Skin Structure and Barrier Properties

    OpenAIRE

    James-Smith, Monica A.; Hellner, Brittney; Annunziato, Nancy; Mitragotri, Samir

    2010-01-01

    We investigated the effect of two commonly studied surfactants, sodium dodecyl sulfate (SDS) and dodecyl trimethylammonium bromide (C12TAB), on skin barrier properties. Using skin conductivity, FT-IR of stratum corneum samples, and penetration of radiolabelled SDS, we determined that addition of C12TAB lowers the ability of SDS to perturb skin’s barrier properties. Ultrafiltration experiments revealed that addition of C12TAB serves to decrease the concentration of monomers and sub-micellar ag...

  18. Thermally Driven Pure Spin and Valley Currents via the Anomalous Nernst Effect in Monolayer Group-VI Dichalcogenides

    DEFF Research Database (Denmark)

    Yu, Xiao-Qin; Zhu, Zhen-Gang; Su, Gang;

    2015-01-01

    The spin and valley-dependent anomalous Nernst effects are analyzed for monolayer MoS2 and other group-VI dichalcogenides. We find that pure spin and valley currents can be generated perpendicular to the applied thermal gradient in the plane of these two-dimensional materials. This effect provides...

  19. Effects of uranium compounds on skin

    International Nuclear Information System (INIS)

    The following uranium compounds were topically applied to the dorsal skin of 35 day-old Wistar rats (60 g, male): uranium dioxide, uranyl nitrate, uranyl acetate, ammonium uranyl tricarbonate and ammonium diuranate. Percutaneous absorption was mediated with the aid of a vehicle and known quantities of various particle-sized batches of uranium compounds were directly implanted in the subcutaneous tissue. Animals were sacrificed 3, 6, 24 and 48 hours after implantation. Subcutaneous tissue and muscle underneath the implantation site were anlaysed by light and electron microscopy. A Cameca 322 X-ray microanalyzer was used to analyze uranium traces in calcified tissue (bones and teeth) and kidneys. A steady loss in body weight was observed in animals given high concentration of uranyl nitrate and ammonium uranyl tricarbonate. All animals died five days after the onset of the experiment due to renal failure. Slightly soluble compounds, ammonium diuranate and uranyl acetate, caused only a slight decrease in body weight. Uranium dioxide, the most insoluble compound used, induced only a transitory slight body weight decrease. Histopathological study revealed damages to the tissues of topicated skin, hair follicles and adnexal glands. High concentration of uranium was indicated in bone, teeth and kidneys by X-ray scanning

  20. Theory of Multifarious Quantum Phases and Large Anomalous Hall Effect in Pyrochlore Iridate Thin Films.

    Science.gov (United States)

    Hwang, Kyusung; Kim, Yong Baek

    2016-01-01

    We theoretically investigate emergent quantum phases in the thin film geometries of the pyrochore iridates, where a number of exotic quantum ground states are proposed to occur in bulk materials as a result of the interplay between electron correlation and strong spin-orbit coupling. The fate of these bulk phases as well as novel quantum states that may arise only in the thin film platforms, are studied via a theoretical model that allows layer-dependent magnetic structures. It is found that the magnetic order develop in inhomogeneous fashions in the thin film geometries. This leads to a variety of magnetic metal phases with modulated magnetic ordering patterns across different layers. Both the bulk and boundary electronic states in these phases conspire to promote unusual electronic properties. In particular, such phases are akin to the Weyl semimetal phase in the bulk system and they would exhibit an unusually large anomalous Hall effect. PMID:27418293

  1. Theory for the anomalous electron transport in Hall effect thrusters. II. Kinetic model

    Science.gov (United States)

    Lafleur, T.; Baalrud, S. D.; Chabert, P.

    2016-05-01

    In Paper I [T. Lafleur et al., Phys. Plasmas 23, 053502 (2016)], we demonstrated (using particle-in-cell simulations) the definite correlation between an anomalously high cross-field electron transport in Hall effect thrusters (HETs), and the presence of azimuthal electrostatic instabilities leading to enhanced electron scattering. Here, we present a kinetic theory that predicts the enhanced scattering rate and provides an electron cross-field mobility that is in good agreement with experiment. The large azimuthal electron drift velocity in HETs drives a strong instability that quickly saturates due to a combination of ion-wave trapping and wave-convection, leading to an enhanced mobility many orders of magnitude larger than that expected from classical diffusion theory. In addition to the magnetic field strength, B0, this enhanced mobility is a strong function of the plasma properties (such as the plasma density) and therefore does not, in general, follow simple 1 /B02 or 1 /B0 scaling laws.

  2. Theory of Multifarious Quantum Phases and Large Anomalous Hall Effect in Pyrochlore Iridate Thin Films

    Science.gov (United States)

    Hwang, Kyusung; Kim, Yong Baek

    2016-01-01

    We theoretically investigate emergent quantum phases in the thin film geometries of the pyrochore iridates, where a number of exotic quantum ground states are proposed to occur in bulk materials as a result of the interplay between electron correlation and strong spin-orbit coupling. The fate of these bulk phases as well as novel quantum states that may arise only in the thin film platforms, are studied via a theoretical model that allows layer-dependent magnetic structures. It is found that the magnetic order develop in inhomogeneous fashions in the thin film geometries. This leads to a variety of magnetic metal phases with modulated magnetic ordering patterns across different layers. Both the bulk and boundary electronic states in these phases conspire to promote unusual electronic properties. In particular, such phases are akin to the Weyl semimetal phase in the bulk system and they would exhibit an unusually large anomalous Hall effect. PMID:27418293

  3. Anomalous hysteresis loops measured by magneto-optical Kerr effect in Ni/rubrene bilayers

    Energy Technology Data Exchange (ETDEWEB)

    Li, Wen; Fronk, Michael; Kupfer, Hartmut; Schulze, Steffen; Hietschold, Michael; Albrecht, Manfred; Zahn, Dietrich R.T.; Salvan, Georgeta [Institute of Physics, Chemnitz University of Technology (Germany); Springer, Felix [Department of Physics, University of Konstanz (Germany)

    2010-07-01

    Metal/organic heterostructures formed by the deposition of metals on organic films find a wide application range in organic electronics and spintronics. In this work Ni(14 nm)/rubrene(15 nm) bilayers were fabricated by subsequent deposition in ultra-high vacuum. For the very low evaporation rate used for the rubrene deposition, the bilayer morphology is characterized by large, well separated islands. The magnetic and structural properties of the heterostructure were probed by SQUID, AFM and TEM measurements, respectively. The magneto-optical Kerr effect (MOKE) of this ferromagnetic/organic bilayer was measured in the energy range from 1.5 eV to 5.5 eV. At photon energies near the zero crossing point in the real part of the MOKE spectrum, anomalous hysteresis shapes were obtained. The numerical analysis of the MOKE hysteresis at several photon energies reveals the combination of two components with orthogonal magnetization or different anisotropy.

  4. Anomalous Brownian motion of colloidal particle in a nematic environment: effect of the director fluctuations

    Directory of Open Access Journals (Sweden)

    T. Turiv

    2015-06-01

    Full Text Available As recently reported [Turiv T. et al., Science, 2013, Vol. 342, 1351], fluctuations in the orientation of the liquid crystal (LC director can transfer momentum from the LC to a colloid, such that the diffusion of the colloid becomes anomalous on a short time scale. Using video microscopy and single particle tracking, we investigate random thermal motion of colloidal particles in a nematic liquid crystal for the time scales shorter than the expected time of director fluctuations. At long times, compared to the characteristic time of the nematic director relaxation we observe typical anisotropic Brownian motion with the mean square displacement (MSD linear in time τ and inversly proportional to the effective viscosity of the nematic medium. At shorter times, however, the dynamics is markedly nonlinear with MSD growing more slowly (subdiffusion or faster (superdiffusion than τ. These results are discussed in the context of coupling of colloidal particle's dynamics to the director fluctuation dynamics.

  5. 3d Transition Metal Adsorption Induced the valley-polarized Anomalous Hall Effect in Germanene.

    Science.gov (United States)

    Zhou, P; Sun, L Z

    2016-01-01

    Based on DFT + U and Berry curvature calculations, we study the electronic structures and topological properties of 3d transition metal (TM) atom (from Ti to Co) adsorbed germanene (TM-germanene). We find that valley-polarized anomalous Hall effect (VAHE) can be realized in germanene by adsorbing Cr, Mn, or Co atoms on its surface. A finite valley Hall voltage can be easily detected in their nanoribbon, which is important for valleytronics devices. Moreover, different valley-polarized current and even reversible valley Hall voltage can be archived by shifting the Fermi energy of the systems. Such versatile features of the systems show potential in next generation electronics devices. PMID:27312176

  6. Evidence of local effects in anomalous refraction and focusing properties of dodecagonal photonic quasicrystals

    Science.gov (United States)

    di Gennaro, Emiliano; Miletto, Carlo; Savo, Salvatore; Andreone, Antonello; Morello, Davide; Galdi, Vincenzo; Castaldi, Giuseppe; Pierro, Vincenzo

    2008-05-01

    We present the key results from a comprehensive study of the refraction and focusing properties of a two-dimensional dodecagonal photonic “quasicrystal” (PQC), which was carried out via both full-wave numerical simulations and microwave measurements on a slab made of alumina rods inserted in a parallel-plate waveguide. We observe an anomalous refraction and focusing in several frequency regions, which confirm some recently published results. However, our interpretation, which is based on numerical and experimental evidence, substantially differs from the one in terms of “effective negative refractive index” that was originally proposed. Instead, our study highlights the critical role played by short-range interactions associated with local order and symmetry.

  7. Anomalous Hall effect and magnetoresistance behavior in Co/Pd1−xAgx multilayers

    KAUST Repository

    Guo, Z. B.

    2013-02-13

    In this paper, we report anomalous Hall effect (AHE) correlated with the magnetoresistance behavior in [Co/Pd1-xAg x]n multilayers. For the multilayers with n = 6, the increase in Ag content from x = 0 to 0.52 induces the change in AHE sign from negative surface scattering-dominated AHE to positive interface scattering-dominated AHE, which is accompanied with the transition from anisotropy magnetoresistance (AMR) dominated transport to giant magnetoresistance (GMR) dominated transport. For n = 80, scaling analysis with Rs ∝ρ xx γ yields γ ∼ 3.44 for x = 0.52 which presents GMR-type transport, in contrast to γ ∼ 5.7 for x = 0 which presents AMR-type transport. © 2013 American Institute of Physics.

  8. Anomalous effects of dopant distribution in Ge single crystals grown by FZ-technique aboard spacecrafts

    Science.gov (United States)

    Kartavykh, A. V.; Kopeliovich, E. S.; Mil'vidskii, M. G.; Rakov, V. V.

    1999-09-01

    The gallium distribution in nine germanium single crystals, all grown with similar heat conditions using the floating zone (FZ) method aboard five unmanned "Photon" spacecrafts (SC), from melts doped from 1×10 18 to 1×10 20 at/cm 3 are studied. For the first time, the strong anomalous concentration dependence of the distribution coefficient (from 0.16 to 0.089, respectively), having no "earth" analogue, was revealed experimentally as a result of comparative studies of space-grown and reference crystals. It also was shown, that the revealed dependence can completely define the longitudinal dopant distribution profile in a single crystal. The hypothesis of the nature of the observed effect was proposed, which consists of an intensification of the mixing processes in the heavily doped molten zone, restricted by free surface, caused by an increase of the surface-active impurity content in reduced gravity.

  9. Theory of Multifarious Quantum Phases and Large Anomalous Hall Effect in Pyrochlore Iridate Thin Films

    Science.gov (United States)

    Hwang, Kyusung; Kim, Yong Baek

    2016-07-01

    We theoretically investigate emergent quantum phases in the thin film geometries of the pyrochore iridates, where a number of exotic quantum ground states are proposed to occur in bulk materials as a result of the interplay between electron correlation and strong spin-orbit coupling. The fate of these bulk phases as well as novel quantum states that may arise only in the thin film platforms, are studied via a theoretical model that allows layer-dependent magnetic structures. It is found that the magnetic order develop in inhomogeneous fashions in the thin film geometries. This leads to a variety of magnetic metal phases with modulated magnetic ordering patterns across different layers. Both the bulk and boundary electronic states in these phases conspire to promote unusual electronic properties. In particular, such phases are akin to the Weyl semimetal phase in the bulk system and they would exhibit an unusually large anomalous Hall effect.

  10. Quantum anomalous Hall effect in atomic crystal layers from in-plane magnetization

    Science.gov (United States)

    Ren, Yafei; Zeng, Junjie; Deng, Xinzhou; Yang, Fei; Pan, Hui; Qiao, Zhenhua

    2016-08-01

    We theoretically demonstrate that with in-plane magnetization, the quantum anomalous Hall effect (QAHE) can be realized in two-dimensional atomic crystal layers with preserved inversion symmetry but broken out-of-plane mirror reflection symmetry. By taking the honeycomb lattice system as an example, we find that the low-buckled structure satisfying the symmetry criteria is crucial to induce QAHE. The topologically nontrivial bulk gap carrying a Chern number of C =±1 opens in the vicinity of the saddle points M , where the band dispersion exhibits strong anisotropy. We further show that the QAHE with electrically tunable Chern number can be achieved in Bernal-stacked multilayer systems, and the applied interlayer potential differences can dramatically decrease the critical magnetization to make the QAHE experimentally feasible.

  11. The temperature dependent anomalous Hall effect in La-Ca-Mn-O films

    International Nuclear Information System (INIS)

    The colossal magnetoresistance of La1-xCaxMnO3 has been reported in many experiments. The authors present their study of the anomalous Hall effect in epitaxial La0.67Ca0.33MnO3 thin films. They have measured the temperature dependence of resistivity, magnetization and AHE coefficients between 300K and 5K for the samples grown on different substrates. From these studies, the relation between the resistivity and AHE coefficient as well as the temperature dependence of AHE coefficient are explored. The results show that the direction of AHE is reversed below approximately 100K. This sign reversal is discussed in term of the change of band structure and the co-existence of hole-like and electron-like conduction

  12. Anomalous finite-size effects in the Battle of the Sexes

    CERN Document Server

    Cremer, Jonas; Frey, Erwin

    2007-01-01

    The Battle of the Sexes describes asymmetric conflicts in mating behavior of males and females. Males can be philanderer or faithful, while females are either fast or coy, leading to a cyclic dynamics. The adjusted replicator equation predicts stable coexistence of all four strategies. In this situation, we consider the effects of fluctuations stemming from a finite population size. We show that they unavoidably lead to extinction of two strategies in the population. However, the typical time until extinction occurs strongly prolongs with increasing system size. In the meantime, a quasi-stationary probability distribution forms that is anomalously flat in the vicinity of the coexistence state. This behavior originates in a vanishing linear deterministic drift near the fixed point. We provide numerical data as well as an analytical approach to the mean extinction time and the quasi-stationary probability distribution.

  13. Anomalous Magnetohydrodynamics

    OpenAIRE

    Giovannini, Massimo

    2013-01-01

    Anomalous symmetries induce currents which can be parallel rather than orthogonal to the hypermagnetic field. Building on the analogy with charged liquids at high magnetic Reynolds numbers, the persistence of anomalous currents is scrutinized for parametrically large conductivities when the plasma approximation is accurate. Different examples in globally neutral systems suggest that the magnetic configurations minimizing the energy density with the constraint that the helicity be conserved co...

  14. Anomalous Hall effect in a ferromagnetic Fe3Sn2 single crystal with a geometrically frustrated Fe bilayer kagome lattice

    Science.gov (United States)

    Wang, Qi; Sun, Shanshan; Zhang, Xiao; Pang, Fei; Lei, Hechang

    2016-08-01

    The anomalous Hall effect (AHE) is investigated for a ferromagnetic Fe3Sn2 single crystal with a geometrically frustrated kagome bilayer of Fe. The scaling behavior between anomalous Hall resistivity ρxy A and longitudinal resistivity ρx x is quadratic and further analysis implies that the AHE in the Fe3Sn2 single crystal should be dominated by the intrinsic Karplus-Luttinger mechanism rather than extrinsic skew-scattering or side-jump mechanisms. Moreover, there is a sudden jump of anomalous Hall conductivity σxy A appearing at about 100 K where the spin-reorientation transition from the c axis to the a b plane is completed. This change of σxy A might be related to the evolution of the Fermi surface induced by the spin-reorientation transition.

  15. Characterization of ionizing radiation effects on human skin allografts

    International Nuclear Information System (INIS)

    The skin has a fundamental role in the viability of the human body. In the cases of extensive wounds, allograft skin provides an alternative to cover temporarily the damaged areas. After donor screening and preservation in glycerol (above 85%), the skin can be stored in the Skin Banks. The glycerol at this concentration has a bacteriostatic effect after certain time of preservation. On the other hand, skin sterilization by ionizing radiation may reduces the quarantine period for transplantation in patients and its safety is considered excellent. The objectives of this work were to establish procedures using two sources of ionizing radiation for sterilization of human skin allograft, and to evaluate the skin after gamma and electron beam irradiation. The analysis of stress-strain intended to verify possible effects of the radiation on the structure of preserved grafts. Skin samples were submitted to doses of 25 kGy and 50 kGy in an irradiator of 60Co and in an electron beam accelerator. Morphology and ultra-structure studies were also accomplished. The samples irradiated with a dose of 25 kGy seemed to maintain the bio mechanic characteristics. The gamma irradiated samples with a dose of 50 kGy and submitted to an electron beam at doses of 25 kGy and 50 kGy presented significant differences in the values of the elasticity modulus, in relation to the control. The analysis of the ultramicrographies revealed modifications in the structure and alterations in the pattern of collagen fibrils periodicity of the irradiated samples. (author)

  16. Effect of skin wettedness on sweat gland response

    Science.gov (United States)

    Nadel, E. R.; Stolwijk, J. A. J.

    1973-01-01

    Investigation of the effect of skin wettedness upon sweating rate. Several techniques were used to gain a better understanding of the quantitative nature of this effect. The results include the finding that the evaporative power of the environment has a profound effect on the relationship between body temperature and sweating rate.

  17. Skin photoprotection by green tea: antioxidant and immunomodulatory effects.

    Science.gov (United States)

    Katiyar, Santosh K

    2003-09-01

    Because of a characteristic aroma and health benefits, green tea is consumed worldwide as a popular beverage. The epicatechin derivatives, commonly called polyphenols, present in green tea possess antioxidant, anti-inflammatory and anti-carcinogenic properties. The major and most highly chemopreventive constituent in green tea responsible for the biochemical or pharmacological effects is (-)-epigallocatechin-3-gallate (EGCG). Epidemiological, clinical and biological studies have implicated that solar ultraviolet (UV) light is a complete carcinogen and repeated exposure can lead to the development of various skin disorders including melanoma and nonmelanoma skin cancers. We and others have shown that topical treatment or oral consumption of green tea polyphenols (GTP) inhibit chemical carcinogen- or UV radiation-induced skin carcinogenesis in different laboratory animal models. Topical treatment of GTP and EGCG or oral consumption of GTP resulted in prevention of UVB-induced inflammatory responses, immunosuppression and oxidative stress, which are the biomarkers of several skin disease states. Topical application of GTP and EGCG prior to exposure of UVB protects against UVB-induced local as well as systemic immune suppression in laboratory animals, which was associated with the inhibition of UVB-induced infiltration of inflammatory leukocytes. Prevention of UVB-induced suppression of immune responses by EGCG was also associated with the reduction in immunosuppressive cytokine interleukin (IL)-10 production at UV irradiated skin and draining lymph nodes, whereas IL-12 production was significantly enhanced in draining lymph nodes. Antioxidant and anti-inflammatory effects of green tea were also observed in human skin. Treatment of EGCG to human skin resulted in the inhibition of UVB-induced erythema, oxidative stress and infiltration of inflammatory leukocytes. We also showed that treatment of GTP to human skin prevents UVB-induced cyclobutane pyrimidine dimers

  18. Anomalous Chiral Superfluidity

    OpenAIRE

    Lublinsky, Michael(Physics Department, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel); Zahed, Ismail

    2009-01-01

    We discuss both the anomalous Cartan currents and the energy-momentum tensor in a left chiral theory with flavour anomalies as an effective theory for flavored chiral phonons in a chiral superfluid with the gauged Wess-Zumino-Witten term. In the mean-field (leading tadpole) approximation the anomalous Cartan currents and the energy momentum tensor take the form of constitutive currents in the chiral superfluid state. The pertinence of higher order corrections and the Adler-Bardeen theorem is ...

  19. Effects of a skin neuropeptide (substance p on cutaneous microflora.

    Directory of Open Access Journals (Sweden)

    Lily Mijouin

    Full Text Available BACKGROUND: Skin is the largest human neuroendocrine organ and hosts the second most numerous microbial population but the interaction of skin neuropeptides with the microflora has never been investigated. We studied the effect of Substance P (SP, a peptide released by nerve endings in the skin on bacterial virulence. METHODOLOGY/PRINCIPAL FINDINGS: Bacillus cereus, a member of the skin transient microflora, was used as a model. Exposure to SP strongly stimulated the cytotoxicity of B. cereus (+553±3% with SP 10(-6 M and this effect was rapid (<5 min. Infection of keratinocytes with SP treated B. cereus led to a rise in caspase1 and morphological alterations of the actin cytoskeleton. Secretome analysis revealed that SP stimulated the release of collagenase and superoxide dismutase. Moreover, we also noted a shift in the surface polarity of the bacteria linked to a peel-off of the S-layer and the release of S-layer proteins. Meanwhile, the biofilm formation activity of B. cereus was increased. The Thermo unstable ribosomal Elongation factor (Ef-Tu was identified as the SP binding site in B. cereus. Other Gram positive skin bacteria, namely Staphylococcus aureus and Staphylococcus epidermidis also reacted to SP by an increase of virulence. Thermal water from Uriage-les-Bains and an artificial polysaccharide (Teflose® were capable to antagonize the effect of SP on bacterial virulence. CONCLUSIONS/SIGNIFICANCE: SP is released in sweat during stress and is known to be involved in the pathogenesis of numerous skin diseases through neurogenic inflammation. Our study suggests that a direct effect of SP on the skin microbiote should be another mechanism.

  20. Radon exposure of the skin: I. Biological effects

    International Nuclear Information System (INIS)

    Radon progeny can plate out on skin and give rise to exposure of the superficial epidermis from alpha emitters Po-218 (7.7 MeV, range ∼66 μm) and Po-214 (6 MeV, range ∼44 μm). Dose rates from beta/gamma emitters Pb-214 and Bi-214 are low and only predominate at depths in excess of the alpha range. This paper reviews the evidence for a causal link between exposure from radon and its progeny, and deterministic and stochastic biological effects in human skin. Radiation induced skin effects such as ulceration and dermal atrophy, which require irradiation of the dermis, are ruled out for alpha irradiation from radon progeny because the target cells are considerably deeper than the range of alpha particles. They have not been observed in man or animals. Effects such as erythema and acute epidermal necrosis have been observed in a few cases of very high dose alpha particle exposures in man and after acute high dose exposure in animals from low energy beta radiations with similar depth doses to radon progeny. The required skin surface absorbed doses are in excess of 100 Gy. Such effects would require extremely high levels of radon progeny. They would involve quite exceptional circumstances, way outside the normal range of radon exposures in man. There is no definitive identification of the target cells for skin cancer induction in animals or man. The stem cells in the basal layer which maintain the epidermis are the most plausible contenders for target cells. The majority of these cells are near the end of the range of radon progeny alpha particles, even on the thinnest body sites. The nominal depth of these cells, as recommended by the International Commission on Radiological Protection (ICRP), is 70 μm. There is evidence however that some irradiation of the hair follicles and/or the deeper dermis, as well as the inter-follicular epidermis, is also necessary for skin cancer induction. Alpha irradiation of rodent skin that is restricted to the epidermis does not

  1. Radon exposure of the skin: I. Biological effects

    Energy Technology Data Exchange (ETDEWEB)

    Charles, M W [School of Physics and Astronomy, University of Birmingham, Edgbaston, Birmingham B15 2TT (United Kingdom)

    2007-09-15

    Radon progeny can plate out on skin and give rise to exposure of the superficial epidermis from alpha emitters Po-218 (7.7 MeV, range {approx}66 {mu}m) and Po-214 (6 MeV, range {approx}44 {mu}m). Dose rates from beta/gamma emitters Pb-214 and Bi-214 are low and only predominate at depths in excess of the alpha range. This paper reviews the evidence for a causal link between exposure from radon and its progeny, and deterministic and stochastic biological effects in human skin. Radiation induced skin effects such as ulceration and dermal atrophy, which require irradiation of the dermis, are ruled out for alpha irradiation from radon progeny because the target cells are considerably deeper than the range of alpha particles. They have not been observed in man or animals. Effects such as erythema and acute epidermal necrosis have been observed in a few cases of very high dose alpha particle exposures in man and after acute high dose exposure in animals from low energy beta radiations with similar depth doses to radon progeny. The required skin surface absorbed doses are in excess of 100 Gy. Such effects would require extremely high levels of radon progeny. They would involve quite exceptional circumstances, way outside the normal range of radon exposures in man. There is no definitive identification of the target cells for skin cancer induction in animals or man. The stem cells in the basal layer which maintain the epidermis are the most plausible contenders for target cells. The majority of these cells are near the end of the range of radon progeny alpha particles, even on the thinnest body sites. The nominal depth of these cells, as recommended by the International Commission on Radiological Protection (ICRP), is 70 {mu}m. There is evidence however that some irradiation of the hair follicles and/or the deeper dermis, as well as the inter-follicular epidermis, is also necessary for skin cancer induction. Alpha irradiation of rodent skin that is restricted to the

  2. Skin Effect in Electromagnetism and Asymptotic Behaviour of Skin Depth for High Conductivity

    OpenAIRE

    Péron, Victor; Caloz, Gabriel; Dauge, Monique; Faou, Erwan

    2010-01-01

    International audience We study a three-dimensional model for the skin effect in electromagnetism. The 3-D case of the Maxwell equations in harmonic regime on a domain composed of a dielectric and of a highly conducting material is considered. We derive an asymptotic expansion with respect to a small parameter related to high conductivity. This expansion is theoretically justified at any order. The asymptotic expansion and numerical simulations in axisymmetric geometry exhibit the influenc...

  3. Testing dependence of anomalous Hall effect on resistivity in SrRuO3 by its increase with electron irradiation

    NARCIS (Netherlands)

    Haham, N.; Konczykowski, M.; Kuiper, B.; Koster, G.; Klein, L.

    2013-01-01

    We measure the anomalous Hall effect (AHE) in several patterns of the itinerant ferromagnet SrRuO 3 before and after the patterns are irradiated with electrons. The irradiation increases the resistivity of the patterns due to the introduction of point defects and we find that the AHE coefficient R

  4. Measurement of the nucleation and domain depinning field in a single Co/Pt multilayer dot by anomalous Hall effect

    NARCIS (Netherlands)

    Delalande, M.; Vries, de J.; Abelmann, L.; Lodder, J.C.

    2012-01-01

    Co/Pt multilayer dots with perpendicular anisotropy and with diameters of 250 and 350 nm were fabricated on top of a Hall cross configuration. The angular dependence of the magnetic reversal of the individual dot was investigated by Anomalous Hall effect measurements. At near in-plane angles (85° wi

  5. Vacuum effects in magnetic field with with account for fermion anomalous magnetic moment and axial-vector interaction

    Science.gov (United States)

    Bubnov, Andrey; Gubina, Nadezda; Zhukovsky, Vladimir

    2016-05-01

    We study vacuum polarization effects in the model of Dirac fermions with additional interaction of an anomalous magnetic moment with an external magnetic field and fermion interaction with an axial-vector condensate. The proper time method is used to calculate the one-loop vacuum corrections with consideration for different configurations of the characteristic parameters of these interactions.

  6. Fractional Identification of Rotor Skin Effect in Induction Machines

    Directory of Open Access Journals (Sweden)

    Jean-Claude Trigeassou

    2011-07-01

    Full Text Available Fractional identification of rotor skin effect in induction machines is presented in this paper. Park transformation is used to obtain a system of differential equations which allows to include the skin effect in the rotor bars of asynchronous machines. A transfer function with a fractional derivative order has been selected to represent the admittance of the bar by the help of a non integer integrator which is approximated by a J+1 dimensional modal system. The machine parameters are estimated by an output-error technique using a non linear iterative optimization algorithm. Numerical simulations and experimental results show the performance of the modal approach for modeling and identification.

  7. The effect of grape-skin extract on oxidative status

    DEFF Research Database (Denmark)

    Young, J. F.; Dragsted, L. O.; Daneshvar, B.;

    2000-01-01

    Epidemiological studies indicate that moderate alcohol consumption, particularly wine, reduce the risk of CHD. The present study was designed to investigate the effect of grape-skin extract on markers of oxidative status. The study was designed as a randomised crossover. A diet with a low content...... of flavonoids was served with strict control of intake in two consecutive 1-week intervention periods to fifteen subjects (nine women, six men) divided randomly into two groups. During one of the weeks the subjects from either group consumed 200 ml grape-skin extract in water (1 mg extract/ml) at each of three...... daily meals (31.3 mg total phenolics, including 9.0 mg catechin). An increased activity of glutathione reductase and a borderline increase of glutathione peroxidase activity in erythrocytes were observed after grape-skin intervention, while the intervention had no significant effect on superoxide...

  8. The effect of pregnancy on paternal skin allograft survival

    Institute of Scientific and Technical Information of China (English)

    SHOU ZhangFei; XU YiFang; XIAO HuaYing; ZHOU Qin; CAI JieRu; YANG Yi; JIANG Hong; ZHANG WenJie; CHEN JiangHua

    2009-01-01

    Elucidation of maternal-fetal tolerance mechanisms clarifies the role of regulatory T cells (Treg)in transplant tolerance.This study aim to investigate the effect of pregnancy on paternal skin allograft survival.Flow cytometry techniques,mixed lymphocytes reaction (MLR),PCR,real-time PCR and skin transplantation were key methods.Treg increased significantly from 4.2% before pregnancy to peak at 6.8% day 8 after pregnancy.Both heme oxygenase-1 (HO-1)and indoleamine 2,3-dioxygenase (IDO)mRNA express high in placenta while low in spleen (P<0.05).Although Treg increased during pregnancy,and splenocytes from the pregnant mice showed lower MLR response toward the paternal stimulator,single time pregnancy showed no significant protective effect on paternal skin allograft survival in the tested condition.

  9. The effect of grape-skin extract on oxidative status

    DEFF Research Database (Denmark)

    Young, J. F.; Dragsted, L. O.; Daneshvar, B.;

    2000-01-01

    Epidemiological studies indicate that moderate alcohol consumption, particularly wine, reduce the risk of CHD. The present study was designed to investigate the effect of grape-skin extract on markers of oxidative status. The study was designed as a randomised crossover. A diet with a low content...... of flavonoids was served with strict control of intake in two consecutive 1-week intervention periods to fifteen subjects (nine women, six men) divided randomly into two groups. During one of the weeks the subjects from either group consumed 200 ml grape-skin extract in water (1 mg extract/ml) at...... each of three daily meals (31.3 mg total phenolics, including 9.0 mg catechin). An increased activity of glutathione reductase and a borderline increase of glutathione peroxidase activity in erythrocytes were observed after grape-skin intervention, while the intervention had no significant effect on...

  10. The effect of pregnancy on paternal skin allograft survival

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Elucidation of maternal-fetal tolerance mechanisms clarifies the role of regulatory T cells (Treg) in transplant tolerance. This study aim to investigate the effect of pregnancy on paternal skin allograft survival. Flow cytometry techniques, mixed lymphocytes reaction (MLR), PCR, real-time PCR and skin transplantation were key methods. Treg increased significantly from 4.2% before pregnancy to peak at 6.8% day 8 after pregnancy. Both heme oxygenase-1 (HO-1) and indoleamine 2,3-dioxygenase (IDO) mRNA express high in placenta while low in spleen (P<0.05). Although Treg increased during pregnancy, and splenocytes from the pregnant mice showed lower MLR response toward the paternal stimulator, single time pregnancy showed no significant protective effect on paternal skin allograft survival in the tested condition.

  11. Application of focused-beam flat-sample method to synchrotron powder X-ray diffraction with anomalous scattering effect

    Science.gov (United States)

    Tanaka, M.; Katsuya, Y.; Matsushita, Y.

    2013-03-01

    The focused-beam flat-sample method (FFM), which is a method for high-resolution and rapid synchrotron X-ray powder diffraction measurements by combination of beam focusing optics, a flat shape sample and an area detector, was applied for diffraction experiments with anomalous scattering effect. The advantages of FFM for anomalous diffraction were absorption correction without approximation, rapid data collection by an area detector and good signal-to-noise ratio data by focusing optics. In the X-ray diffraction experiments of CoFe2O4 and Fe3O4 (By FFM) using X-rays near the Fe K absorption edge, the anomalous scattering effect between Fe/Co or Fe2+/Fe3+ can be clearly detected, due to the change of diffraction intensity. The change of observed diffraction intensity as the incident X-ray energy was consistent with the calculation. The FFM is expected to be a method for anomalous powder diffraction.

  12. Quantum anomalous Hall effect in time-reversal-symmetry breaking topological insulators

    Science.gov (United States)

    Chang, Cui-Zu; Li, Mingda

    2016-03-01

    The quantum anomalous Hall effect (QAHE), the last member of Hall family, was predicted to exhibit quantized Hall conductivity {σyx}=\\frac{{{e}2}}{h} without any external magnetic field. The QAHE shares a similar physical phenomenon with the integer quantum Hall effect (QHE), whereas its physical origin relies on the intrinsic topological inverted band structure and ferromagnetism. Since the QAHE does not require external energy input in the form of magnetic field, it is believed that this effect has unique potential for applications in future electronic devices with low-power consumption. More recently, the QAHE has been experimentally observed in thin films of the time-reversal symmetry breaking ferromagnetic (FM) topological insulators (TI), Cr- and V- doped (Bi,Sb)2Te3. In this topical review, we review the history of TI based QAHE, the route to the experimental observation of the QAHE in the above two systems, the current status of the research of the QAHE, and finally the prospects for future studies.

  13. Anomalous Hall effect sensors based on magnetic element doped topological insulator thin films

    Science.gov (United States)

    Ni, Yan; Zhang, Zhen; Nlebedim, Ikenna; Jiles, David

    Anomalous Hall effect (AHE) is recently discovered in magnetic element doped topological insulators (TIs), which promises low power consumption highly efficient spintronics and electronics. This discovery broaden the family of Hall effect (HE) sensors. In this work, both HE and AHE sensor based on Mn and Cr doped Bi2Te3 TI thin films will be systematically studied. The influence of Mn concentration on sensitivity of MnxBi2-xTe3 HE sensors will be discussed. The Hall sensitivity increase 8 times caused by quantum AHE will be reported. AHE senor based on Cr-doped Bi2Te3 TI thin films will also be studied and compared with Mn doped Bi2Te3 AHE sensor. The influence of thickness on sensitivity of CrxBi2-xTe3 AHE sensors will be discussed. Ultrahigh Hall sensitivity is obtained in Cr doped Bi2Te3. The largest Hall sensitivity can reach 2620 Ω/T in sensor which is almost twice higher than that of the normal semiconductor HE sensor. Our work indicates that magnetic element doped topological insulator with AHE are good candidates for ultra-sensitive Hall effect sensors.

  14. Quantum anomalous Hall effect in time-reversal-symmetry breaking topological insulators.

    Science.gov (United States)

    Chang, Cui-Zu; Li, Mingda

    2016-03-31

    The quantum anomalous Hall effect (QAHE), the last member of Hall family, was predicted to exhibit quantized Hall conductivity σ(yx) = e2/h without any external magnetic field. The QAHE shares a similar physical phenomenon with the integer quantum Hall effect (QHE), whereas its physical origin relies on the intrinsic topological inverted band structure and ferromagnetism. Since the QAHE does not require external energy input in the form of magnetic field, it is believed that this effect has unique potential for applications in future electronic devices with low-power consumption. More recently, the QAHE has been experimentally observed in thin films of the time-reversal symmetry breaking ferromagnetic (FM) topological insulators (TI), Cr- and V- doped (Bi,Sb)2Te3. In this topical review, we review the history of TI based QAHE, the route to the experimental observation of the QAHE in the above two systems, the current status of the research of the QAHE, and finally the prospects for future studies. PMID:26934535

  15. Anomalous Higgs couplings

    CERN Document Server

    González-Garciá, M Concepción

    1999-01-01

    We review the effects of new effective interactions on Higgs-boson phenomenology. New physics in the electroweak bosonic sector is expected to induce additional interactions between the Higgs doublet field and the electroweak gauge bosons, leading to anomalous Higgs couplings as well as anomalous gauge-boson self-interactions. Using a linearly realized SU(2)/sub L/*U(1)/sub Y/ invariant effective Lagrangian to describe the bosonic sector of the Standard Model, we review the effects of the new effective interactions on the Higgs- boson production rates and decay modes. We summarize the results from searches for the new Higgs signatures induced by the anomalous interactions in order to constrain the scale of new physics, in particular at CERN LEP and Fermilab Tevatron colliders. (43 refs).

  16. The foreign exchange market: return distributions, multifractality, anomalous multifractality and the Epps effect

    Science.gov (United States)

    Drożdż, Stanisław; Kwapień, Jarosław; Oświȩcimka, Paweł; Rak, Rafał

    2010-10-01

    We present a systematic study of various statistical characteristics of high-frequency returns from the foreign exchange market. This study is based on six exchange rates forming two triangles: EUR-GBP-USD and GBP-CHF-JPY. It is shown that the exchange rate return fluctuations for all of the pairs considered are well described by the non-extensive statistics in terms of q-Gaussians. There exist some small quantitative variations in the non-extensivity q-parameter values for different exchange rates (which depend also on the time scales studied), and this can be related to the importance of a given exchange rate in the world's currency trade. Temporal correlations organize the series of returns such that they develop the multifractal characteristics for all of the exchange rates, with a varying degree of symmetry of the singularity spectrum f(α), however. The most symmetric spectrum is identified for the GBP/USD. We also form time series of triangular residual returns and find that the distributions of their fluctuations develop disproportionately heavier tails as compared to small fluctuations, which excludes description in terms of q-Gaussians. The multifractal characteristics of these residual returns reveal such anomalous properties as negative singularity exponents and even negative singularity spectra. Such anomalous multifractal measures have so far been considered in the literature in connection with diffusion-limited aggregation and with turbulence. Studying the cross-correlations among different exchange rates, we found that market inefficiency on short time scales leads to the occurrence of the Epps effect on much longer time scales, but comparable to the ones for the stock market. Although the currency market is much more liquid than the stock markets and has a much greater transaction frequency, the building up of correlations takes up to several hours—a duration that does not differ much from what is observed in the stock markets. This may suggest

  17. Strong and Anomalous Thermal Expansion Precedes the Thermosalient Effect in Dynamic Molecular Crystals

    Science.gov (United States)

    Panda, Manas K.; Centore, Roberto; Causà, Mauro; Tuzi, Angela; Borbone, Fabio; Naumov, Panče

    2016-01-01

    The ability of thermosalient solids, organic analogues of inorganic martensites, to move by rapid mechanical reconfiguration or ballistic event remains visually appealing and potentially useful, yet mechanistically elusive phenomenon. Here, with a material that undergoes both thermosalient and non-thermosalient phase transitions, we demonstrate that the thermosalient effect is preceded by anomalous thermal expansion of the unit cell. The crystal explosion occurs as sudden release of the latent strain accumulated during the anisotropic, exceedingly strong expansion of the unit cell with αa = 225.9 × 10−6 K−1, αb = 238.8 × 10−6 K−1 and αc = −290.0 × 10−6 K−1, the latter being the largest negative thermal expansivity observed for an organic compound thus far. The results point out to the occurence of the thermosalient effect in phase transitions as means to identify new molecular materials with strong positive and/or negative thermal expansion which prior to this work could only be discovered serendipitously. PMID:27403616

  18. Strong and Anomalous Thermal Expansion Precedes the Thermosalient Effect in Dynamic Molecular Crystals.

    Science.gov (United States)

    Panda, Manas K; Centore, Roberto; Causà, Mauro; Tuzi, Angela; Borbone, Fabio; Naumov, Panče

    2016-01-01

    The ability of thermosalient solids, organic analogues of inorganic martensites, to move by rapid mechanical reconfiguration or ballistic event remains visually appealing and potentially useful, yet mechanistically elusive phenomenon. Here, with a material that undergoes both thermosalient and non-thermosalient phase transitions, we demonstrate that the thermosalient effect is preceded by anomalous thermal expansion of the unit cell. The crystal explosion occurs as sudden release of the latent strain accumulated during the anisotropic, exceedingly strong expansion of the unit cell with αa = 225.9 × 10(-6) K(-1), αb = 238.8 × 10(-6) K(-1) and αc = -290.0 × 10(-6) K(-1), the latter being the largest negative thermal expansivity observed for an organic compound thus far. The results point out to the occurence of the thermosalient effect in phase transitions as means to identify new molecular materials with strong positive and/or negative thermal expansion which prior to this work could only be discovered serendipitously. PMID:27403616

  19. Shell effects and α particle anomalous yield in reactions With nucleons

    International Nuclear Information System (INIS)

    The results of the spectra and cross section calculations for nucleons, alpha-particle and gamma-emission are discussed. The calculations were performed in the framework of the statistical theory of nuclear reactions for the nucleons interacting with 208Pb nuclei at energies up to 50 MeV. It is shown that the use for the level density of Fermi gas model and of systematics based on the neutron resonance density data results in an anomalously big alpha-yield at the first evaporation step if the incident nucleon energy exceeds 30 MeV. The shell effect damping leads to the decrease in difference between level density in competing channels. Alpha-particle yield strongly diminishes as compared to neutron one. Therefore the relative value of neutron and alpha-particle emission cross sections could indicate to the conservation of the shell structure at high excitation energies. The comparison with experiment confirms the conclusions concerning the shell effects damping at high excitation energies

  20. Magnetoresistance and anomalous Hall effect of reactive sputtered polycrystalline Ti1 - XCrxN films

    KAUST Repository

    Duan, Xiaofei

    2013-09-01

    The reactive-sputtered polycrystalline Ti1 - xCrxN films with 0.17 ≤ x ≤ 0.51 are ferromagnetic and at x = 0.47 the Curie temperature TC shows a maximum of ~ 120 K. The films are metallic at 0 ≤ x ≤ 0.47, while the films with x = 0.51 and 0.78 are semiconducting-like. The upturn of resistivity below 70 K observed in the films with 0.10 ≤ x ≤ 0.47 is from the effects of the electron-electron interaction and weak localization. The negative magnetoresistance (MR) of the films with 0.10 ≤ x ≤ 0.51 is dominated by the double-exchange interaction, while at x = 0.78, MR is related to the localized magnetic moment scattering at the grain boundaries. The scaling ρxyA/n ∝ ρxx2.19 suggests that the anomalous Hall effect in the polycrystalline Ti1 - xCrxN films is scattering-independent. © 2013 Elsevier B.V. All rights reserved.

  1. Pretreatment Effects of Moxibustion on the Skin Permeation and the Skin and Muscle Concentration of Drugs

    OpenAIRE

    曹, 殿秀

    2008-01-01

    This study was conducted to evaluate the ln vlvo pretreatment effects of moxibustion on the ln vitro skin permeation ef weak ionized macromolecular compound FITC-dextran (mean molecular weight of 4 kDa, FD-4 ) and ion compound sodium salicylate, and on ln vivodistribution of ion drug sodium salicylate. The direct and indirect moxibustion or indirect aromatic incense (0.10 g moxa or aromatic cylinder) were pretreated consecutive four times once every 5 minutes on the abdominal surface of hairl...

  2. Inhibitory Effect of Corn Silk on Skin Pigmentation

    Directory of Open Access Journals (Sweden)

    Sang Yoon Choi

    2014-03-01

    Full Text Available In this study, the inhibitory effect of corn silk on melanin production was evaluated. This study was performed to investigate the inhibitory effect of corn silk on melanin production in Melan-A cells by measuring melanin production and protein expression. The corn silk extract applied on Melan-A cells at a concentration of 100 ppm decreased melanin production by 37.2% without cytotoxicity. This was a better result than arbutin, a positive whitening agent, which exhibited a 26.8% melanin production inhibitory effect at the same concentration. The corn silk extract did not suppress tyrosinase activity but greatly reduced the expression of tyrosinase in Melan-A cells. In addition, corn silk extract was applied to the human face with hyperpigmentation, and skin color was measured to examine the degree of skin pigment reduction. The application of corn silk extract on faces with hyperpigmentation significantly reduced skin pigmentation without abnormal reactions. Based on the results above, corn silk has good prospects for use as a material for suppressing skin pigmentation.

  3. Neutral cloud theory of the Jovian nebula: Anomalous ionization effect of superthermal electrons

    Science.gov (United States)

    Barbosa, D. D.

    1994-01-01

    The standard model of the Jovian nebula postulates that its particle source is the extended cloud of neutral sulfur and oxygen atoms that escape from the satellite Io and become ionized through electron impact from the corotating plasma. Its energy source is the gyroenergy acquired by newly formed pickup ions as they are swept up to corotation velocity by the planetary magnetic field. Elastic collisions between plasma ions and electrons cool the ions and heat the electrons, while inelastic collisions cool the electrons and excite the ions to radiate intense line emission, which is the primary energy-loss mechanism for the plasma. This neutral cloud theory of the Io plasma torus, as it has come to be known, has been the subject of recent critcism which asserts that the theory cannot account for the observed charge state of the plasma which features O(+) and S(2+) as the dominant ions. It is shown in this work that the inclusion of a small population of super-thermal electrons is required to achieve the correct ion partitioning among various charge states. It is also argued that the anomalous ionization effect of the superthermal electrons is responsible for the overall spatial bifurcation of the nebula into a hot multiply charged plasma region outside of 5.7 Jovian radii and a cool singly ionized plasma inside this distance.

  4. Anomalous transport model study of chiral magnetic effects in heavy ion collisions

    Science.gov (United States)

    Sun, Yifeng; Ko, Che Ming; Li, Feng

    2016-10-01

    Using an anomalous transport model for massless quarks and antiquarks, we study the effect of a magnetic field on the elliptic flows of quarks and antiquarks in relativistic heavy ion collisions. With initial conditions from a blast wave model and assuming that the strong magnetic field produced in noncentral heavy ion collisions can last for a sufficiently long time, we obtain an appreciable electric quadrupole moment in the transverse plane of a heavy ion collision. The electric quadrupole moment subsequently leads to a splitting between the elliptic flows of quarks and antiquarks. The slope of the charge asymmetry dependence of the elliptic flow difference between positively and negatively charged particles is positive, which is expected from the chiral magnetic wave formed in the produced QGP and observed in experiments at the BNL Relativistic Heavy Ion Collider, only if the Lorentz force acting on the charged particles is neglected and the quark-antiquark scattering is assumed to be dominated by the chirality changing channel.

  5. Magnetic modulation doping in topological insulators toward higher-temperature quantum anomalous Hall effect

    Energy Technology Data Exchange (ETDEWEB)

    Mogi, M., E-mail: mogi@cmr.t.u-tokyo.ac.jp; Yoshimi, R.; Yasuda, K.; Kozuka, Y. [Department of Applied Physics and Quantum Phase Electronics Center (QPEC), University of Tokyo, Tokyo 113-8656 (Japan); Tsukazaki, A. [Institute for Materials Research, Tohoku University, Sendai 980-8577 (Japan); PRESTO, Japan Science and Technology Agency (JST), Chiyoda-ku, Tokyo 102-0075 (Japan); Takahashi, K. S. [RIKEN Center for Emergent Matter Science (CEMS), Wako 351-0198 (Japan); Kawasaki, M.; Tokura, Y. [Department of Applied Physics and Quantum Phase Electronics Center (QPEC), University of Tokyo, Tokyo 113-8656 (Japan); RIKEN Center for Emergent Matter Science (CEMS), Wako 351-0198 (Japan)

    2015-11-02

    Quantum anomalous Hall effect (QAHE), which generates dissipation-less edge current without external magnetic field, is observed in magnetic-ion doped topological insulators (TIs) such as Cr- and V-doped (Bi,Sb){sub 2}Te{sub 3}. The QAHE emerges when the Fermi level is inside the magnetically induced gap around the original Dirac point of the TI surface state. Although the size of gap is reported to be about 50 meV, the observable temperature of QAHE has been limited below 300 mK. We attempt magnetic-Cr modulation doping into topological insulator (Bi,Sb){sub 2}Te{sub 3} films to increase the observable temperature of QAHE. By introducing the rich-Cr-doped thin (1 nm) layers at the vicinity of both the surfaces based on non-Cr-doped (Bi,Sb){sub 2}Te{sub 3} films, we have succeeded in observing the QAHE up to 2 K. The improvement in the observable temperature achieved by this modulation-doping appears to be originating from the suppression of the disorder in the surface state interacting with the rich magnetic moments. Such a superlattice designing of the stabilized QAHE may pave a way to dissipation-less electronics based on the higher-temperature and zero magnetic-field quantum conduction.

  6. High-Temperature Quantum Anomalous Hall Effect in n -p Codoped Topological Insulators

    Science.gov (United States)

    Qi, Shifei; Qiao, Zhenhua; Deng, Xinzhou; Cubuk, Ekin D.; Chen, Hua; Zhu, Wenguang; Kaxiras, Efthimios; Zhang, S. B.; Xu, Xiaohong; Zhang, Zhenyu

    2016-07-01

    The quantum anomalous Hall effect (QAHE) is a fundamental quantum transport phenomenon that manifests as a quantized transverse conductance in response to a longitudinally applied electric field in the absence of an external magnetic field, and it promises to have immense application potential in future dissipationless quantum electronics. Here, we present a novel kinetic pathway to realize the QAHE at high temperatures by n -p codoping of three-dimensional topological insulators. We provide a proof-of-principle numerical demonstration of this approach using vanadium-iodine (V-I) codoped Sb2 Te3 and demonstrate that, strikingly, even at low concentrations of ˜2 % V and ˜1 % I, the system exhibits a quantized Hall conductance, the telltale hallmark of QAHE, at temperatures of at least ˜50 K , which is 3 orders of magnitude higher than the typical temperatures at which it has been realized to date. The underlying physical factor enabling this dramatic improvement is tied to the largely preserved intrinsic band gap of the host system upon compensated n -p codoping. The proposed approach is conceptually general and may shed new light in experimental realization of high-temperature QAHE.

  7. The Thermal Effects of Therapeutic Lasers with 810 and 904nm Wavelengths on Human Skin

    OpenAIRE

    Joensen, Jon; Demmink, Jan Hendrik; Johnson, Mark I; Iversen, Vegard Vereide; Lopes-Martins, Rodrigo Álvaro Brandão; Bjordal, Jan Magnus

    2011-01-01

    Objective: To investigate the effect of therapeutic infrared class 3B laser irradiation on skin temperature in healthy participants of differing skin color, age, and gender. Background: Little is known about the potential thermal effects of Low Level Laser Therapy (LLLT) irradiation on human skin. Methods: Skin temperature was measured in 40 healthy volunteers with a thermographic camera at laser irradiated and control (non-irradiated) areas on the skin. Six irradiation doses (2–1...

  8. Beer and beer compounds: physiological effects on skin health.

    Science.gov (United States)

    Chen, W; Becker, T; Qian, F; Ring, J

    2014-02-01

    Beer is one of the earliest human inventions and globally the most consumed alcoholic beverage in terms of volume. In addition to water, the 'German Beer Purity Law', based on the Bavarian Beer Purity Law from 1516, allows only barley, hops, yeasts and water for beer brewing. The extracts of these ingredients, especially the hops, contain an abundance of polyphenols such as kaempferol, quercetin, tyrosol, ferulic acid, xanthohumol/isoxanthohumol/8-prenylnaringenin, α-bitter acids like humulone and β-bitter acids like lupulone. 8-prenylnaringenin is the most potent phytoestrogen known to date. These compounds have been shown to possess various anti-bacterial, anti-inflammatory, anti-oxidative, anti-angiogenic, anti-melanogenic, anti-osteoporotic and anti-carcinogenic effects. Epidemiological studies on the association between beer drinking and skin disease are limited while direct evidence of beer compounds in clinical application is lacking. Potential uses of these substances in dermatology may include treatment of atopic eczema, contact dermatitis, pigmentary disorders, skin infections, skin ageing, skin cancers and photoprotections, which require an optimization of the biostability and topical delivery of these compounds. Further studies are needed to determine the bioavailability of these compounds and their possible beneficial health effects when taken by moderate beer consumption.

  9. Beer and beer compounds: physiological effects on skin health.

    Science.gov (United States)

    Chen, W; Becker, T; Qian, F; Ring, J

    2014-02-01

    Beer is one of the earliest human inventions and globally the most consumed alcoholic beverage in terms of volume. In addition to water, the 'German Beer Purity Law', based on the Bavarian Beer Purity Law from 1516, allows only barley, hops, yeasts and water for beer brewing. The extracts of these ingredients, especially the hops, contain an abundance of polyphenols such as kaempferol, quercetin, tyrosol, ferulic acid, xanthohumol/isoxanthohumol/8-prenylnaringenin, α-bitter acids like humulone and β-bitter acids like lupulone. 8-prenylnaringenin is the most potent phytoestrogen known to date. These compounds have been shown to possess various anti-bacterial, anti-inflammatory, anti-oxidative, anti-angiogenic, anti-melanogenic, anti-osteoporotic and anti-carcinogenic effects. Epidemiological studies on the association between beer drinking and skin disease are limited while direct evidence of beer compounds in clinical application is lacking. Potential uses of these substances in dermatology may include treatment of atopic eczema, contact dermatitis, pigmentary disorders, skin infections, skin ageing, skin cancers and photoprotections, which require an optimization of the biostability and topical delivery of these compounds. Further studies are needed to determine the bioavailability of these compounds and their possible beneficial health effects when taken by moderate beer consumption. PMID:23802910

  10. Sensory neuropeptide effects in human skin.

    OpenAIRE

    Fuller, R W; Conradson, T B; Dixon, C M; Crossman, D.C.; Barnes, P. J.

    1987-01-01

    1 Neuropeptides released from sensory nerves may account for cutaneous flare and wheal following local trauma. In 28 normal subjects we have studied the effects of four sensory neuropeptides given by intradermal injection on the forearm or back. 2 All peptides caused a flare distant from the site of injection, presumably due to an axon reflex. Substance P (SP) was the most potent (geometric mean dose causing 50% of maximum flare, 4.2 pmol). Neurokinin A (NKA) was the next most potent with neu...

  11. Effect of band filling on anomalous Hall conductivity and magneto-crystalline anisotropy in NiFe epitaxial thin films

    Directory of Open Access Journals (Sweden)

    Zhong Shi

    2016-01-01

    Full Text Available The anomalous Hall effect (AHE and magneto-crystalline anisotropy (MCA are investigated in epitaxial NixFe1−x thin films grown on MgO (001 substrates. The scattering independent term b of anomalous Hall conductivity shows obvious correlation with cubic magneto-crystalline anisotropy K1. When nickel content x decreasing, both b and K1 vary continuously from negative to positive, changing sign at about x = 0.85. Ab initio calculations indicate NixFe1−x has more abundant band structures than pure Ni due to the tuning of valence electrons (band fillings, resulting in the increased b and K1. This remarkable correlation between b and K1 can be attributed to the effect of band filling near the Fermi surface.

  12. Intrinsic Quantum Anomalous Hall Effect in the Kagome Lattice Cs2 LiMn3 F12

    Science.gov (United States)

    Xu, Gang; Lian, Biao; Zhang, Shou-Cheng; Zhang's Group Team

    In a kagome lattice, the time reversal symmetry can be broken by a staggered magnetic flux emerging from the ferromagnetic ordering and intrinsic spin-orbit coupling, leading to several well-separated nontrivial Chern bands and intrinsic quantum anomalous Hall effect. Based on this idea and ab initio calculations, we propose the realization of the intrinsic quantum anomalous Hall effect in the single layer Cs2Mn3F12 kagome lattice and on the (001) surface of a Cs2LiMn3F12 single crystal by modifying the carrier coverage on it, where the band gap is around 20 meV. Moreover, a simplified tight binding model based on the inplane dd σ antibonding states is constructed to understand the topological band structures of the system.

  13. Stability and anomalous compressibility of Bose gases near resonance: The scale-dependent interactions and thermal effects

    Science.gov (United States)

    Jiang, Shao-Jian; Zhou, Fei

    2015-07-01

    The stability of Bose gases near resonance has been a puzzling problem in recent years. In this article, we demonstrate that in addition to generating thermal pressure, thermal atoms enhance the repulsiveness of the scale-dependent interactions between condensed atoms due to a renormalization effect and further stabilize the Bose gases. Consequently, we find that, as a precursor of instability, the compressibility develops an anomalous structure as a function of scattering length and is drastically reduced compared with the mean-field value. Furthermore, the density profile of a Bose gas in a harmonic trap is found to develop a flat top near the center. This is due to the anomalous behavior of compressibility and can be a potential smoking gun for probing such an effect.

  14. Effect of band filling on anomalous Hall conductivity and magneto-crystalline anisotropy in NiFe epitaxial thin films

    International Nuclear Information System (INIS)

    The anomalous Hall effect (AHE) and magneto-crystalline anisotropy (MCA) are investigated in epitaxial NixFe1−x thin films grown on MgO (001) substrates. The scattering independent term b of anomalous Hall conductivity shows obvious correlation with cubic magneto-crystalline anisotropy K1. When nickel content x decreasing, both b and K1 vary continuously from negative to positive, changing sign at about x = 0.85. Ab initio calculations indicate NixFe1−x has more abundant band structures than pure Ni due to the tuning of valence electrons (band fillings), resulting in the increased b and K1. This remarkable correlation between b and K1 can be attributed to the effect of band filling near the Fermi surface

  15. Effect of band filling on anomalous Hall conductivity and magneto-crystalline anisotropy in NiFe epitaxial thin films

    Energy Technology Data Exchange (ETDEWEB)

    Shi, Zhong; Jiang, Hang-Yu; Zhou, Shi-Ming, E-mail: shiming@tongji.edu.cn [Shanghai Key Laboratory of Special Artificial Microstructure Materials and Technology & Pohl Institute of Solid State Physics, School of Physics Science and Engineering, Tongji University, Shanghai 200092 (China); Hou, Yan-Liang; Ye, Quan-Lin [Department of Physics, Hangzhou Normal University, Hangzhou 310036 (China); Su Si, Ming [Key Laboratory for Magnetism and Magnetic Materials of the Ministry of Education, Lanzhou University, Lanzhou 730000 (China)

    2016-01-15

    The anomalous Hall effect (AHE) and magneto-crystalline anisotropy (MCA) are investigated in epitaxial Ni{sub x}Fe{sub 1−x} thin films grown on MgO (001) substrates. The scattering independent term b of anomalous Hall conductivity shows obvious correlation with cubic magneto-crystalline anisotropy K{sub 1}. When nickel content x decreasing, both b and K{sub 1} vary continuously from negative to positive, changing sign at about x = 0.85. Ab initio calculations indicate Ni{sub x}Fe{sub 1−x} has more abundant band structures than pure Ni due to the tuning of valence electrons (band fillings), resulting in the increased b and K{sub 1}. This remarkable correlation between b and K{sub 1} can be attributed to the effect of band filling near the Fermi surface.

  16. Room-temperature anomalous Hall effect and magnetroresistance in (Ga, Co)-codoped ZnO diluted magnetic semiconductor films

    Institute of Scientific and Technical Information of China (English)

    Liu Xue-Chao; Chen Zhi-Zhan; Shi Er-Wei; Liao Da-Qian; Zhou Ke-Jin

    2011-01-01

    This paper reports that the (Ga, Co)-codoped ZnO thin films have been grown by inductively coupled plasma enhanced physical vapour deposition. Room-temperature ferromagnetism is observed for the as-grown thin films. The x-ray absorption fine structure characterization reveals that Co2+ and Ga3+ ions substitute for Zn2+ ions in the ZnO lattice and exclude the possibility of extrinsic ferromagnetism origin. The ferromagnetic (Ga, Co)-codoped ZnO thin films exhibit carrier concentration dependent anomalous Hall effect and positive magnetoresistance at room temperature. The mechanism of anomalous Hall effect and magneto-transport in ferromagnetic ZnO-based diluted magnetic semiconductors is discussed.

  17. Effect of Age on Tooth Shade, Skin Color and Skin-Tooth Color Interrelationship in Saudi Arabian Subpopulation

    Science.gov (United States)

    Haralur, Satheesh B

    2015-01-01

    Background: Dental restoration or prosthesis in harmony with adjacent natural teeth color is indispensable part for the successful esthetic outcome. The studies indicate is existence of correlation between teeth and skin color. Teeth and skin color are changed over the aging process. The aim of the study was to explore the role of age on the tooth and skin color parameters, and to investigate the effect of ageing on teeth-skin color correlation. Materials and Methods: Total of 225 Saudi Arabian ethnic subjects was divided into three groups of 75 each. The groups were divided according to participant’s age. The participant’s age for Group I, Group II, and Group III was 18-29 years, 30-50 years, and above 50 years, respectively. The tooth color was identified by spectrophotometer in CIE Lab parameters. The skin color was registered with skin surface photography. The data were statistically analyzed with one-way ANOVA and correlation tests with SPSS 18 software. Results: The Group I had the highest ‘L’ value of 80.26, Group III recorded the least value of 76.66. The Group III had highest yellow value ‘b’ at 22.72, while Group I had 19.19. The skin ‘L’ value was highest in the young population; the elder population had the increased red value ‘a’ in comparison to younger subjects. The ‘L’ tooth color parameter had a strong positive linear correlation with skin color in young and adult subjects. While Group III teeth showed the strong positive correlation with ‘b’ parameter at malar region. Conclusion: The elder subjects had darker and yellow teeth in comparison with younger subjects. The reddening of the skin was observed as age-related skin color change. The age had a strong influence on the teeth-skin color correlation. PMID:26464536

  18. Note on anomalous Higgs-boson couplings in effective field theory

    Directory of Open Access Journals (Sweden)

    G. Buchalla

    2015-11-01

    Full Text Available We propose a parametrization of anomalous Higgs-boson couplings that is both systematic and practical. It is based on the electroweak chiral Lagrangian, including a light Higgs boson, as the effective field theory (EFT at the electroweak scale v. This is the appropriate framework for the case of sizeable deviations in the Higgs couplings of order 10% from the Standard Model, considered to be parametrically larger than new-physics effects in the sector of electroweak gauge interactions. The role of power counting in identifying the relevant parameters is emphasized. The three relevant scales, v, the scale of new Higgs dynamics f, and the cut-off Λ=4πf, admit expansions in ξ=v2/f2 and f2/Λ2. The former corresponds to an organization of operators by their canonical dimension, the latter by their loop order or chiral dimension. In full generality the EFT is thus organized as a double expansion. However, as long as ξ≫1/16π2 the EFT systematics is closer to the chiral counting. The leading effects in the consistent approximation provided by the EFT, relevant for the presently most important processes of Higgs production and decay, are given by a few (typically six couplings. These parameters allow us to describe the properties of the Higgs boson in a general and systematic way, and with a precision adequate for the measurements to be performed at the LHC. The framework can be systematically extended to include loop corrections and higher-order terms in the EFT.

  19. Note on anomalous Higgs-boson couplings in effective field theory

    Science.gov (United States)

    Buchalla, G.; Catà, O.; Celis, A.; Krause, C.

    2015-11-01

    We propose a parametrization of anomalous Higgs-boson couplings that is both systematic and practical. It is based on the electroweak chiral Lagrangian, including a light Higgs boson, as the effective field theory (EFT) at the electroweak scale v. This is the appropriate framework for the case of sizeable deviations in the Higgs couplings of order 10% from the Standard Model, considered to be parametrically larger than new-physics effects in the sector of electroweak gauge interactions. The role of power counting in identifying the relevant parameters is emphasized. The three relevant scales, v, the scale of new Higgs dynamics f, and the cut-off Λ = 4 πf, admit expansions in ξ =v2 /f2 and f2 /Λ2. The former corresponds to an organization of operators by their canonical dimension, the latter by their loop order or chiral dimension. In full generality the EFT is thus organized as a double expansion. However, as long as ξ ≫ 1 / 16π2 the EFT systematics is closer to the chiral counting. The leading effects in the consistent approximation provided by the EFT, relevant for the presently most important processes of Higgs production and decay, are given by a few (typically six) couplings. These parameters allow us to describe the properties of the Higgs boson in a general and systematic way, and with a precision adequate for the measurements to be performed at the LHC. The framework can be systematically extended to include loop corrections and higher-order terms in the EFT.

  20. Local orbitals approach to the anomalous Hall and Nernst effects in itinerant ferromagnets

    Directory of Open Access Journals (Sweden)

    Středa Pavel

    2014-07-01

    Full Text Available Linear response of the orbital momentum to the gradient of the chemical potential is used to obtain anomalous Hall conductivity. Transition from the ideal Bloch system for which the conductivity is determined by the Berry phase curvatures to the case of strong disorder for which the conductivity becomes dependent on the relaxation time is analysed. Presented tight-binding model reproduces experimentally observed qualitative features of the anomalous Hall conductivity and the transverse Peltier coefficient in the so called bad-metal and scattering-independent regimes.

  1. Effect of Skin to Skin Contact on Maternal State Anxiety in a Cesarean Section Ward

    Directory of Open Access Journals (Sweden)

    Hamid Haghani

    2011-01-01

    Full Text Available Introduction: This study aimed at investigating the effect of skin to skin contact (SSC on maternal state anxiety (MSA in cesarean section unit in Akbarabadi Hospital in Tehran. Methods: In a randomized controlled trial, 60 Iranian mothers with at least one record of cesarean section delivery were assigned to two intervention (SSC and control groups. In the morning shift and two hours after the operation, as a routine postoperative care, pain-killers were given to all mothers. Then the mothers’ pain scores were measured using visual analog scale (VAS. If VAS was≤3, MSA was measured by using the State-Trait Anxiety Inventory (STAI Scale (Spiel Berger. Thirty minutes of SSC intervention was done for mothers in the intervention group. Six hours later, in case VAS was ≤ 3, MSA was re-measured by using the Spiel Berger Scale for all mothers. Results: Six hours after implementing the intervention, there were no meaningful statistical differences between the MSA mean scores of the two groups, but severity of MSA in intervention group was less than that of the control group (P=0.037. Six hours after the intervention, there was a significant decrease in the MSA mean score in SSC group (P=0.002. Conclusion: As regards the important role of constant anxiety in developing postpartum depression, and as the results of this study indicate, SSC is recommended in postpartum and especially cesarean section wards.

  2. Local effects of immunosuppressants in the skin and impact on UV carcinogenesis

    OpenAIRE

    Voskamp, Pieter

    2012-01-01

    Skin cancer is a serious problem for many organ transplant recipients. Half of them develop skin cancer within 20 years after the transplantation. The main cause of this increased skin cancer risk is thought to be suppression of the immune system, a necessity to prevent rejection of the transplanted organ. This thesis focuses on the effects of immunosuppressive drugs on the responses of skin cells to UV irradiation and how these altered responses would affect UV-induced skin cancer developmen...

  3. Evaluation of skin viability effect on ethosome and liposome-mediated psoralen delivery via cell uptake.

    Science.gov (United States)

    Zhang, Yong-Tai; Shen, Li-Na; Wu, Zhong-Hua; Zhao, Ji-Hui; Feng, Nian-Ping

    2014-10-01

    This study investigated the effect of skin viability on its permeability to psoralen delivered by ethosomes, as compared with liposomes. With decreasing skin viability, the amount of liposome-delivered psoralen that penetrated through the skin increased, whereas skin deposition of psoralen from both ethosomes and liposomes reduced. Psoralen delivery to human-immortalized epidermal cells was more effective using liposomes, whereas delivery to human embryonic skin fibroblast cells was more effective when ethosomes were used. These findings agreed with those of in vivo studies showing that skin psoralen deposition from ethosomes and liposomes first increased and then plateaued overtime, which may indicate gradual saturation of intracellular drug delivery. It also suggested that the reduced deposition of ethosome- or liposome-delivered psoralen in skin with reduced viability may relate to reduced cellular uptake. This work indicated that the effects of skin viability should be taken into account when evaluating nanocarrier-mediated drug skin permeation. PMID:25070929

  4. Evaluation of skin viability effect on ethosome and liposome-mediated psoralen delivery via cell uptake.

    Science.gov (United States)

    Zhang, Yong-Tai; Shen, Li-Na; Wu, Zhong-Hua; Zhao, Ji-Hui; Feng, Nian-Ping

    2014-10-01

    This study investigated the effect of skin viability on its permeability to psoralen delivered by ethosomes, as compared with liposomes. With decreasing skin viability, the amount of liposome-delivered psoralen that penetrated through the skin increased, whereas skin deposition of psoralen from both ethosomes and liposomes reduced. Psoralen delivery to human-immortalized epidermal cells was more effective using liposomes, whereas delivery to human embryonic skin fibroblast cells was more effective when ethosomes were used. These findings agreed with those of in vivo studies showing that skin psoralen deposition from ethosomes and liposomes first increased and then plateaued overtime, which may indicate gradual saturation of intracellular drug delivery. It also suggested that the reduced deposition of ethosome- or liposome-delivered psoralen in skin with reduced viability may relate to reduced cellular uptake. This work indicated that the effects of skin viability should be taken into account when evaluating nanocarrier-mediated drug skin permeation.

  5. The effect of various avocado oils on skin collagen metabolism.

    Science.gov (United States)

    Werman, M J; Mokady, S; Nimni, M E; Neeman, I

    1991-01-01

    The effects of various avocado oils on collagen metabolism in skin were studied in growing rats fed diets containing 10% (w/w) of the tested oils. Rats fed the unrefined avocado oil extracted with hexane from the intact fruit, its unsaponifiables or the avocado seed oil, showed significant increases in soluble collagen content in skin, though total collagen content was not affected. The increased soluble collagen content appears to be a consequence of the inhibition of lysyl oxidase activity. The active factor was found to be present in the unrefined avocado oil and probably originated from the avocado seed, since collagen metabolism was affected only by fractions which contained lipids fraction from the seed. In comparison rats fed the refined or unrefined soybean oils showed no effects.

  6. Anomalous chiral superfluidity

    Energy Technology Data Exchange (ETDEWEB)

    Lublinsky, Michael, E-mail: lublinsky@phys.uconn.ed [Department of Physics and Astronomy, Stony Brook University, Stony Brook, NY 11794 (United States); Physics Department, Ben-Gurion University, Beer Sheva 84105 (Israel); Zahed, Ismail [Department of Physics and Astronomy, Stony Brook University, Stony Brook, NY 11794 (United States)

    2010-02-08

    We discuss both the anomalous Cartan currents and the energy-momentum tensor in a left chiral theory with flavor anomalies as an effective theory for flavored chiral phonons in a chiral superfluid with the gauged Wess-Zumino-Witten term. In the mean-field (leading tadpole) approximation the anomalous Cartan currents and the energy-momentum tensor take the form of constitutive currents in the chiral superfluid state. The pertinence of higher order corrections and the Adler-Bardeen theorem is briefly noted.

  7. Anomalous polymer dynamics is non-Markovian: memory effects and the generalized Langevin equation formulation

    NARCIS (Netherlands)

    D. Panja

    2010-01-01

    Any first course on polymer physics teaches that the dynamics of a tagged monomer of a polymer is anomalously subdiffusive, i.e., the mean-square displacement of a tagged monomer increases as tα for some α < 1 until the terminal relaxation time τ of the polymer. Beyond time τ the motion of the tagge

  8. Some anomalous effects of sodium ions on the electrophoretic mobility and heteroaggregation of microgel particles.

    Science.gov (United States)

    Routh, Alexander F; Vincent, Brian

    2004-05-15

    a cationic polystyrene latex sample, prepared with the same amidinium-based initiator. These experiments demonstrate the importance of soluble silicates, leached from glass storage vessels, particularly in the presence of sodium ions. Needless to say, the "anomalous" effects disappeared when plastic storage vessels were used in place of the glass ones.

  9. Thermal effects of X-band microwaves on skin tissues

    Science.gov (United States)

    Song, Kyo D.; Yoon, Hargsoon; Lee, Kunik; Kim, Jaehwan; Choi, Sang H.

    2012-04-01

    Microwave can be used as a power carrier to implanted medical devices wirelessly, which is regarded as one of the attractive features for medical applications. The loss mechanism of microwave transmission through lossy media often appears as a thermal effect due to the absorption of microwave. Such a thermal effect on human tissue has not rigorously studied yet. The thermal effect on living tissues was experimentally tested with animal skins to understand the absorption characteristics of microwave. In this paper, the frequency range of microwave used for the tests was from 6 GHz to 13 GHz.

  10. Chimney Effect Assessment of the Double-skin Facade

    Institute of Scientific and Technical Information of China (English)

    QIU Zhong-zhu; LI Peng; CHOW Tin-tai; REN Jian-xing; WANG Wen-huan

    2009-01-01

    The mathematic model of heat transfer through ventihted double glazing was verified with themeasured data,which were from a test chamber equipped with glass face temperature,solar radiation,ambient temperature,and wind speed measurement facility.Mter the model validation,the double-skin facade assess-ment was carried out through simulation with ESP-r software integrating thermal simulation and air low net work module.The air flow situation in the air gap was analyzed on the basis of the hourly air velocity simulation data within typical winter week,summer week,spring week and autumn week.The differences of chimney ef-fect in different seasons were discussed,and the thermal loads resulted from the ventilated and unventihted dou-ble skin facade were presented.

  11. Influence of defects and disorder on anomalous Hall effect and spin Seebeck effect on permalloy and Heusler compounds

    Energy Technology Data Exchange (ETDEWEB)

    Vilanova Vidal, Enrique

    2012-09-19

    In this work Heusler thin films have been prepared and their transport properties have been studied. Of particularly interest is the anomalous Hall effect (AHE). The effect is a long known but still not fully understood transport effect. Most theory papers focus on the influence of one particular contribution to the AHE. Actual measured experimental data, however, often are not in accordance with idealized assumptions. This thesis discusses the data analysis for materials with low residual resistivity ratios. As prototypical materials, half metallic Heusler compounds are studied. Here, the influence of defects and disorder is apparent in a material with a complex topology of the Fermi surface. Using films with different degrees of disorder, the different scattering mechanisms can be separated. For Co{sub 2}FeSi{sub 0.6}Al{sub 0.4} and Co{sub 2}FeGa{sub 0.5}Ge{sub 0.5}, the AHE induced by B2-type disorder and temperature-dependent scattering is positive, while DO{sub 3}-type disorder and possible intrinsic contributions possess a negative sign. For these compounds, magneto-optical Kerr effects (MOKE) are investigated. First order contributions as a function of intrinsic and extrinsic parameters are qualitatively analyzed. The relation between the crystalline ordering and the second order contributions to the MOKE signal is studied. In addition, sets of the Heusler compound Co{sub 2}MnAl thin films were grown on MgO(100) and Si(100) substrates by radio frequency magnetron sputtering. Composition, magnetic and transport properties were studied systematically for samples deposited at different conditions. In particular, the anomalous Hall effect resistivity presents an extraordinarily temperature independent behavior in a moderate magnetic field range from 0 to 0.6 T. The off-diagonal transport at temperatures up to 300 C was analyzed. The data show the suitability of the material for Hall sensors working well above room temperature. Recently, the spin Seebeck effect

  12. Effects of cream containing ficus carica L. fruit extract on skin parameters: In vivo evaluation

    Directory of Open Access Journals (Sweden)

    H Khan

    2014-01-01

    Full Text Available This study was aimed to investigate the effects of cream containing Ficus carica L. fruit ([Figure 1] extract on various skin parameters such as skin melanin, erythema, moisture content, trans-epidermal water loss and sebum. For this purpose, formulation with 4% concentrated extract of F. carica fruit and base without extract were developed. Base served as a control. Both base and formulation were applied to the cheeks of human volunteers for 8 weeks to investigate the effects on different skin parameters using non-invasive bioengineering instruments. Formulation decreased the skin melanin, trans-epidermal water loss and skin sebum significantly. Formulation increased the skin hydration significantly and insignificant effects on skin erythema. We concluded that a stable topical cream (w/o emulsion containing F. carica fruit extract have effects on skin melanin, trans-epidermal loss, hydration values and sebum content and possibly could be used against for hyper pigmentation, acne, freckles and wrinkle.

  13. Effects of Cream Containing Ficus carica L. Fruit Extract on Skin Parameters: In vivo Evaluation.

    Science.gov (United States)

    Khan, H; Akhtar, N; Ali, A

    2014-01-01

    This study was aimed to investigate the effects of cream containing Ficus carica L. fruit (Fig) extract on various skin parameters such as skin melanin, erythema, moisture content, trans-epidermal water loss and sebum. For this purpose, formulation with 4% concentrated extract of F. carica fruit and base without extract were developed. Base served as a control. Both base and formulation were applied to the cheeks of human volunteers for 8 weeks to investigate the effects on different skin parameters using non-invasive bioengineering instruments. Formulation decreased the skin melanin, trans-epidermal water loss and skin sebum significantly. Formulation increased the skin hydration significantly and insignificant effects on skin erythema. We concluded that a stable topical cream (w/o emulsion) containing F. carica fruit extract have effects on skin melanin, trans-epidermal loss, hydration values and sebum content and possibly could be used against for hyper pigmentation, acne, freckles and wrinkle.

  14. The effect of various dietary fats on skin tumor initiation.

    Science.gov (United States)

    Locniskar, M; Belury, M A; Cumberland, A G; Patrick, K E; Fischer, S M

    1991-01-01

    The type of dietary fat has been shown to modulate the initiation stage of mammary tumorigenesis, with saturated fat fed before and/or during carcinogen treatment resulting in increased tumor incidence. This study was designed to determine whether different types of dietary fat alter the initiation stage of skin carcinogenesis by use of the initiation-promotion mouse skin carcinogenesis model. Sencar mice were divided into three groups and maintained on one of the experimental diets. The AIN-76-based diets consisted of 10% total fat with various types of fat: 8.5% menhaden oil plus 1.5% corn oil, 8.5% coconut oil plus 1.5% corn oil, and 10% corn oil. After three weeks mice were initiated with 10 nmol dimethylbenz[a]anthracene (DMBA). Two weeks later, all mice were switched to a diet containing 5% corn oil. Promotion began four weeks after initiation with twice-weekly application of 1 microgram 12-O-tetradecanoylphorbol-13-acetate and continued for 12 weeks. No statistically significant differences in kilocalories of food consumed or body weights were observed between diet groups during the study. The final papilloma incidence, yield, and size were not significantly different among the diet groups. In a parallel study, [3H]DMBA binding to epidermal DNA showed no dietary differences. Unlike the mammary carcinogenesis model, these data suggest that the type of fat fed during DMBA initiation had minimal effects on this stage of skin carcinogenesis.

  15. Effect of entropy on anomalous transport in electron-temperature-gradient-modes

    Energy Technology Data Exchange (ETDEWEB)

    Yaqub Khan, M., E-mail: myaqubsultani@gmail.com [Department of Basic Sciences, Riphah International University, Islamabad 44000 (Pakistan); National Centre for Physics, Quaid-i-Azam University, Islamabad 45320 (Pakistan); Iqbal, J. [Department of Mathematics, Quaid-i-Azam University, Islamabad 45320 (Pakistan); Ul Haq, A. [Faculty of Engineering and Applied Physics, Riphah International University, Islamabad 44000 (Pakistan)

    2014-05-15

    Due to the interconnection of entropy with temperature and density of plasma, it would be interesting to investigate plasma related phenomena with respect to entropy. By employing Braginskii transport equations, it is proved that entropy is proportional to a function of potential and distribution function of entropy is re-defined, ∇S–drift in obtained. New dispersion relation is derived; it is found that the anomalous transport depends on the gradient of the entropy.

  16. Partial Wave Analysis of Scattering with Nonlocal Aharonov-Bohm Effect and Anomalous Cross Section induced by Quantum Interference

    CERN Document Server

    Lin, D H

    2003-01-01

    Partial wave theory of a three dmensional scattering problem for an arbitray short range potential and a nonlocal Aharonov-Bohm magnetic flux is established. The scattering process of a ``hard shere'' like potential and the magnetic flux is examined. An anomalous total cross section is revealed at the specific quantized magnetic flux at low energy which helps explain the composite fermion and boson model in the fractional quantum Hall effect. Since the nonlocal quantum interference of magnetic flux on the charged particles is universal, the nonlocal effect is expected to appear in quite general potential system and will be useful in understanding some other phenomena in mesoscopic phyiscs.

  17. Air pollution and skin diseases: Adverse effects of airborne particulate matter on various skin diseases.

    Science.gov (United States)

    Kim, Kyung Eun; Cho, Daeho; Park, Hyun Jeong

    2016-05-01

    Environmental air pollution encompasses various particulate matters (PMs). The increased ambient PM from industrialization and urbanization is highly associated with morbidity and mortality worldwide, presenting one of the most severe environmental pollution problems. This article focuses on the correlation between PM and skin diseases, along with related immunological mechanisms. Recent epidemiological studies on the cutaneous impacts of PM showed that PM affects the development and exacerbation of skin diseases. PM induces oxidative stress via production of reactive oxygen species and secretion of pro-inflammatory cytokines such as TNF-α, IL-1α, and IL-8. In addition, the increased production of ROS such as superoxide and hydroxyl radical by PM exposure increases MMPs including MMP-1, MMP-2, and MMP-9, resulting in the degradation of collagen. These processes lead to the increased inflammatory skin diseases and skin aging. In addition, environmental cigarette smoke, which is well known as an oxidizing agent, is closely related with androgenetic alopecia (AGA). Also, ultrafine particles (UFPs) including black carbon and polycyclic aromatic hydrocarbons (PAHs) enhance the incidence of skin cancer. Overall, increased PM levels are highly associated with the development of various skin diseases via the regulation of oxidative stress and inflammatory cytokines. Therefore, anti-oxidant and anti-inflammatory drugs may be useful for treating PM-induced skin diseases. PMID:27018067

  18. Analysis of effect of different construction methods of piles on the end effect on skin friction of piles

    Institute of Scientific and Technical Information of China (English)

    ZHOU Hongbo; CHEN Zhuchang

    2007-01-01

    Based on the comparative analysis of end effect on skin friction of displacement-pile (driven pile),the end effect on skin friction of bored pile is studied.The end effect on skin friction between driven pile and bored pile is different and the end effect on skin friction of bored pile is reduce of skin friction in the soil layer adjacent to the pile end.The degradation degree of skin friction is deduced with the increase of the distance from pile end.The concept of additional mud cake formed by the effect of cushion at the bottom of borehole during pouring concrete is introduced to explain the mechanism of end effect on skin friction of the bored pile.The test results of post-grouting piles indicate that the post-grouting technique is an effective way to improve the end effect on skin friction of bored pile.

  19. Protective effect of gelatin and gelatin hydrolysate from salmon skin on UV irradiation-induced photoaging of mice skin

    Science.gov (United States)

    Chen, Tiejun; Hou, Hu; Lu, Jiaohan; Zhang, Kai; Li, Bafang

    2016-08-01

    The objective of this study was to investigate the effect of gelatin (SG) isolated from salmon skin and its hydrolysate (SGH) on photoaging skin, and the mechanism responsible for anti-photoaging. The average molecular weights of SG and SGH were 65 kDa and 873 Da, respectively. The amino acid compositions of SG and SGH were similar. Both of them were abundant in hydrophobic amino acids. Twenty-five peptides were identified from SGH. SG and SGH could improve UV irradiation-induced pathological changes of macroscopical tissue texture and skin morphology. Hydroxyproline content is an indicator of matrix collagen content, SG and SGH could inhibit the decrease of hydroxyproline content in photoaging skin in a dose dependent manner. In addition, SG and SGH could alleviate UV irradiation-induced oxidative damages to skin by increasing the activities of total superoxide dismutase (T-SOD), glutathione peroxidase (GSH-Px) and catalase (CAT), increasing the content of glutathione (GSH) and decreasing the content of malonaldehyde (MDA). Moreover, SG and SGH could enhance immune regulation system by increasing the thymus index. Thus, the anti-photoaging mechanisms of SG and SGH were by inhibiting the depletion of antioxidant defense components, involving in the synthesis of collagen and enhancing the function of immune system. Besides, SGH showed a better result in protecting skin from photoaging than SG.

  20. Dynamic hysteresis modeling including skin effect using diffusion equation model

    Science.gov (United States)

    Hamada, Souad; Louai, Fatima Zohra; Nait-Said, Nasreddine; Benabou, Abdelkader

    2016-07-01

    An improved dynamic hysteresis model is proposed for the prediction of hysteresis loop of electrical steel up to mean frequencies, taking into account the skin effect. In previous works, the analytical solution of the diffusion equation for low frequency (DELF) was coupled with the inverse static Jiles-Atherton (JA) model in order to represent the hysteresis behavior for a lamination. In the present paper, this approach is improved to ensure the reproducibility of measured hysteresis loops at mean frequency. The results of simulation are compared with the experimental ones. The selected results for frequencies 50 Hz, 100 Hz, 200 Hz and 400 Hz are presented and discussed.

  1. Investigation on the effect of developed product and new food for radiation-induced skin damage

    International Nuclear Information System (INIS)

    In vivo evaluation of the developed pilot product on the skin protection against UV irradiation and screening of new candidate materials. Project Results are Establishment of experimental methods for 3 morphological indices of UV-induced skin damages -Establishment of experimental methods for whitening effect evaluation -Evaluation of HemoHIM administration on the skin damage indices -Evaluation of HemoHIM skin application on the skin damage indices -Evaluation of HemoTonic administration on the skin damage indices -Evaluation of HemoTonic skin application on the skin damage indices -Evaluation of HemoHIM on the antiinflamatory effects in the inflammation stage 1 -Evaluation of HemoHIM on the antiinflamatory effects in the inflammation stage 2 -Evaluation of HemoHIM on the antiinflamatory effects in the inflammation stage 3 -Evaluation of HemoHIM on the antiinflamatory effects in the TNBS-induced colitis -Evaluation of HemoHIM on the anti-wrinkle effects in the skin -Evaluation of HemoHIM on the protective effects on the skin tissue (epidermal thickening, dermal cellularity, dermal cyst) -Evaluation of HemoHIM on the protective effects on the skin tumor development

  2. Investigation on the effect of developed product and new food for radiation-induced skin damage

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sung Ho; Kim, Jong Chun; Bae, Chun Sik; Kim, Se Ra; Lee, Hae Jun; Bang, Dae Won; Lee, Jin Hee; Kim, Joong Sun; Ki, Sun Ah; Song, Myung Seop [Chonnam National University, Gwangju (Korea, Republic of)

    2007-07-15

    In vivo evaluation of the developed pilot product on the skin protection against UV irradiation and screening of new candidate materials. Project Results are Establishment of experimental methods for 3 morphological indices of UV-induced skin damages -Establishment of experimental methods for whitening effect evaluation -Evaluation of HemoHIM administration on the skin damage indices -Evaluation of HemoHIM skin application on the skin damage indices -Evaluation of HemoTonic administration on the skin damage indices -Evaluation of HemoTonic skin application on the skin damage indices -Evaluation of HemoHIM on the antiinflamatory effects in the inflammation stage 1 -Evaluation of HemoHIM on the antiinflamatory effects in the inflammation stage 2 -Evaluation of HemoHIM on the antiinflamatory effects in the inflammation stage 3 -Evaluation of HemoHIM on the antiinflamatory effects in the TNBS-induced colitis -Evaluation of HemoHIM on the anti-wrinkle effects in the skin -Evaluation of HemoHIM on the protective effects on the skin tissue (epidermal thickening, dermal cellularity, dermal cyst) -Evaluation of HemoHIM on the protective effects on the skin tumor development

  3. Effects of Dermal Multipotent Cell Transplantation on Skin Wound Healing

    Institute of Scientific and Technical Information of China (English)

    ShiChunmeng; ChengTianmin; SuYongping; RanXinze; MaiYue; QuJifu; LouShufen; XuHui; LuoChengji

    2005-01-01

    There is increasing evidence that dermis contains adult multipotent stem cells. To investigate the effects of dermis-derived multipotent cells on wound healing, we transplanted a clonal population of dermis-derived multipotent cells (termed as DMCs) by topical and systemic application into the skin wound of rats with simple wounds and rats with combined wound and radiation injury. Our results suggest that both topical and systemic transplantation of DMCs accelerate the healing process in rats with a simple wound; the promoting effect by topical transplantation occurs earlier than systemic transplantation. However, systemic transplantation of DMCs promotes the healing process in irradiated rats, while topical transplantation of DMCs fails. Further studies on the mechanisms of DMCs to promote wound healing indicate that the supernatant of DMCs could promote the proliferation of fibroblasts and epidermal cells; DMCs expressed transcripts of a serics of cytokincs and cxtraccllular matrix molecules, including VEGF, PDGF, HGF, TGF-β, ICAM-1, VCAM-1, and Fibronectin, which were closely related to the wound healing by DNA microarray analysis. The implanted DMCs can engraft into recipient skin wounded tissues after transplantation by the FISH analysis with Y-chromosome-specific probe. Systemic transplantation of DMCs also promotes the recovery of peripheral white blood cells in irradiated rats. These results demonstrate the different effects of DMCs on wound healing in nonirradiated and irradiated rats and illustrate the importance of optimizing wound healing via the topical or systemic transplantation of stem cells.

  4. The giant anomalous Hall effect in the ferromagnet Fe{sub 3}Sn{sub 2}-a frustrated kagome metal

    Energy Technology Data Exchange (ETDEWEB)

    Kida, T; Hagiwara, M [KYOKUGEN, Osaka University, 1-3 Machikaneyama, Toyonaka, Osaka 560-8531 (Japan); Fenner, L A; Dee, A A; Wills, A S [Department of Chemistry, University College London, 20 Gordon Street, London WC1H 0AJ (United Kingdom); Terasaki, I, E-mail: a.s.wills@ucl.ac.uk [Department of Applied Physics, Waseda University, 3-4-1 Okubo, Shinjuku, Tokyo 169-8555 (Japan)

    2011-03-23

    The kagome-bilayer material Fe{sub 3}Sn{sub 2} has recently been shown to be an example of a rare class of magnet-a frustrated ferromagnetic metal. While the magnetism of Fe{sub 3}Sn{sub 2} appears to be relatively simple at high temperature, with localized moments parallel to the c-axis (T{sub C} = 640 K), upon cooling the competing exchange interactions and spin frustration become apparent as they cause the moments to become non-collinear and to rotate towards the kagome plane, forming firstly a canted ferromagnetic structure and then a re-entrant spin glass (T{sub f{approx_equal}}80 K). In this work we show that Fe{sub 3}Sn{sub 2} possesses an unusual anomalous Hall effect. The saturated Hall resistivity of Fe{sub 3}Sn{sub 2} is 3.2 {mu}{Omega} cm at 300 K, almost 20 times higher than that of typical itinerant ferromagnets such as Fe and Ni. The anomalous Hall coefficient R{sub s} is 6.7 x 10{sup -9} {Omega} cm G{sup -1} at 300 K, which is three orders of magnitude larger than that of pure Fe, and obeys an unconventional scaling with the longitudinal resistivity, {rho}{sub xx}, of R{sub s{proportional_to}{rho}xx}{sup 3.15}. Such a relationship cannot be explained by either the conventional skew or side-jump mechanisms, indicating that the anomalous Hall effect in Fe{sub 3}Sn{sub 2} has an extraordinary origin that is presumed to be related to the underlying frustration of the magnetism. These findings demonstrate that frustrated ferromagnets, whether based on bulk materials or on artificial nanoscale structures, can provide new routes to room temperature spin-dependent electron transport properties suited to application in spintronics. (fast track communication)

  5. The effect of skin conditions on patients' quality of life.

    Science.gov (United States)

    Green, L

    Skin conditions can adversely affect many aspects of patients' lives. The quality of life for people with skin conditions such as psoriasis, atopic eczema and acne can be significantly impaired in terms of their psychological wellbeing, social functioning and everyday activities. The significant psychological and social morbidity that occurs in patients with common skin conditions may go unrecognised without appropriate assessment. The level of psychosocial morbidity associated with skin disorders may be underestimated by health professionals. PMID:21141168

  6. The effect of pimecrolimus on expression of genes associated with skin barrier dysfunction in atopic dermatitis skin lesions.

    Science.gov (United States)

    Grzanka, Alicja; Zebracka-Gala, Jadwiga; Rachowska, Regina; Bozek, Andrzej; Kowalska, Małgorzata; Jarzab, Jerzy

    2012-03-01

    The mechanism of action of pimecrolimus (PIM) on atopic lesions is still under consideration. Thus far, we have evidence of its anti-inflammatory and immunomodulatory activity, and recent papers focus on its effect on epidermal barrier function. This study analysed changes in the expression of genes associated with skin barrier dysfunction in atopic dermatitis (AD) skin lesions after 2 weeks of exposure to PIM 1% cream. A real-time quantitative PCR analysis of selected epidermal differentiation complex genes and three alternative pathway keratins was performed in skin biopsies from 11 individuals with AD before and after PIM exposure. The real-time quantitative PCR analysis was compared to non-lesional skin in the same patients. Involucrin, a small proline-rich region (SPRR) 2C gene, and alternative pathway keratin 16 showed significant over-expression in lesional skin followed by significant decrease after PIM therapy. The SPRR1A gene, S100A9, and keratin 6A were also increased; however, the decrease after PIM treatment was not significant. The changes in S100 A2, A7 and A8 followed a similar course with borderline significance. SPRR4 had a significant decrease in expression in lesional versus non-lesional skin, which persisted after PIM treatment. No significant changes were detected in mRNA expression levels of filaggrin and loricrin. Our results suggest that PIM can be effective in restoring the epidermal barrier in patients with AD at least in part by its impact on expression of genes, which are important for the normal barrier function of skin. PMID:22142393

  7. Effects of Ginsenoside Rb1 on Skin Changes

    Directory of Open Access Journals (Sweden)

    Yoshiyuki Kimura

    2012-01-01

    Full Text Available Ginseng roots (Panax ginseng CA Meyer have been used traditionally for the treatment, especially prevention, of various diseases in China, Korea, and Japan. Both experimental and clinical studies suggest ginseng roots to have pharmacological effects in patients with life-style-related diseases such as non-insulin-dependent diabetic mellitus, atherosclerosis, hyperlipidemia, and hypertension. The topical use of ginseng roots to treat skin complaints including atopic suppurative dermatitis, wounds, and inflammation is also described in ancient Chinese texts; however, there have been relatively few studies in this area. In the present paper, we describe introduce the biological and pharmacological effects of ginsenoside Rb1 isolated from Red ginseng roots on skin damage caused by burn-wounds using male Balb/c mice (in vivo and by ultraviolet B irradiation using male C57BL/6J and albino hairless (HR-1 mice (in vivo. Furthermore, to clarify the mechanisms behind these pharmacological actions, human primary keratinocytes and the human keratinocyte cell line HaCaT were used in experiments in vitro.

  8. Effect of skin-pass rolling direction on magnetic properties of semiprocessed nonoriented electrical steel sheets

    Energy Technology Data Exchange (ETDEWEB)

    Kurosaki, Y.; Shimazu, T.; Shiozaki, M.

    1999-09-01

    Effect of skin-pass rolling direction on magnetic properties and directionality in semiprocessed nonoriented electrical steel sheets produced by skin-pass rolling process was studied. Skin-pass rolling direction greatly affects magnetic properties and directionality. By control of skin-pass rolling direction, the value of B{sub 50} in the required directions such as 0{degree}, 90{degree} and circumferential direction can be adjusted and the value of B{sub 50} is higher than that of the usual skin-pass rolling direction of 0{degree}. The textures of the steel sheets developed after batch annealing varied with the skin-pass rolling directions and this result indicates that the residual strain energy by skin-pass rolling varies with skin-pass rolling directions.

  9. Anomalous compressibility effects and superconductivity of EuFe2As2 under high pressures

    Energy Technology Data Exchange (ETDEWEB)

    Uhoya, Walter [University of Alabama, Birmingham; Tsoi, Georgiy [University of Alabama, Birmingham; Vohra, Y. K. [University of Alabama, Birmingham; McGuire, Michael A [ORNL; Sefat, A. S. [Oak Ridge National Laboratory (ORNL); Sales, Brian C [ORNL; Mandrus, David [ORNL; Weir, S. T. [Lawrence Livermore National Laboratory (LLNL)

    2010-01-01

    The crystal structure and electrical resistance of structurally layered EuFe{sub 2}As{sub 2} have been studied up to 70 GPa and down to a temperature of 10 K, using a synchrotron x-ray source and designer diamond anvils. The room temperature compression of the tetragonal phase of EuFe{sub 2}As{sub 2} (I4/mmm) results in an increase in the a-axis length and a rapid decrease in the c-axis length with increasing pressure. This anomalous compression reaches a maximum at 8 GPa and the tetragonal lattice behaves normally above 10 GPa, with a nearly constant c/a axial ratio. The rapid rise in the superconducting transition temperature (T{sub c}) to 41 K with increasing pressure is correlated with this anomalous compression, and a decrease in T{sub c} is observed above 10 GPa. We present P-V data or the equation of state for EuFe{sub 2}As{sub 2} both in the ambient tetragonal phase and in the high pressure collapsed tetragonal phase up to 70 GPa.

  10. Effect of microstructure on anomalous strain-rate-dependent behaviour of bacterial cellulose hydrogel.

    Science.gov (United States)

    Gao, Xing; Shi, Zhijun; Lau, Andrew; Liu, Changqin; Yang, Guang; Silberschmidt, Vadim V

    2016-05-01

    This study is focused on anomalous strain-rate-dependent behaviour of bacterial cellulose (BC) hydrogel that can be strain-rate insensitive, hardening, softening, or strain-rate insensitive in various ranges of strain rate. BC hydrogel consists of randomly distributed nanofibres and a large content of free water; thanks to its ideal biocompatibility, it is suitable for biomedical applications. Motivated by its potential applications in complex loading conditions of body environment, its time-dependent behaviour was studied by means of in-aqua uniaxial tension tests at constant temperature of 37 °C at various strain rates ranging from 0.000 1s(-1) to 0.3s(-1). Experimental results reflect anomalous strain-rate-dependent behaviour that was not documented before. Micro-morphological observations allowed identification of deformation mechanisms at low and high strain rates in relation to microstructural changes. Unlike strain-rate softening behaviours in other materials, reorientation of nanofibres and kinematics of free-water flow dominate the softening behaviour of BC hydrogel at high strain rates. PMID:26952406

  11. Giant gap quantum spin Hall effect and valley-polarized quantum anomalous Hall effect in cyanided bismuth bilayers

    Science.gov (United States)

    Ji, Wei-xiao; Zhang, Chang-wen; Ding, Meng; Zhang, Bao-min; Li, Ping; Li, Feng; Ren, Miao-juan; Wang, Pei-ji; Zhang, Run-wu; Hu, Shu-jun; Yan, Shi-shen

    2016-08-01

    Bismuth (Bi) has attracted a great deal of attention for its strongest spin–orbit coupling (SOC) strength among main group elements. Although quantum anomalous Hall (QAH) state is predicted in half-hydrogenated Bi honeycomb monolayers Bi2H, the experimental results are still missing. Halogen atoms (X = F, Cl and Br) were also frequently used as modifications, but Bi2X films show a frustrating metallic character that masks the QAH effects. Here, first-principle calculations are performed to predict the full-cyanided bismuthene (Bi2(CN)2) as 2D topological insulator supporting quantum spin Hall state with a record large gap up to 1.10 eV, and more importantly, half-cyanogen saturated bismuthene (Bi2(CN)) as a Chern insulator supporting a valley-polarized QAH state, with a Curie temperature to be 164 K, as well as a large gap reaching 0.348 eV which could be further tuned by bi-axial strain and SOC strength. Our findings provide an appropriate and flexible material family candidate for spintronic and valleytronic devices.

  12. The effectiveness of a twice-daily skin-moisturising regimen for reducing the incidence of skin tears.

    Science.gov (United States)

    Carville, Keryln; Leslie, Gavin; Osseiran-Moisson, Rebecca; Newall, Nelly; Lewin, Gill

    2014-08-01

    A cluster randomised controlled trial was conducted to evaluate the effectiveness of a twice-daily moisturising regimen as compared to 'usual' skin care for reducing skin tear incidence. Aged care residents from 14 Western Australian facilities (980 beds) were invited to participate. The facilities were sorted into pairs and matched in terms of bed numbers and whether they provided high or low care. One facility from each matched pair was randomised to the intervention group. Consenting residents in an intervention facility received a twice-daily application of a commercially available, standardised pH neutral, perfume-free moisturiser on their extremities. Residents in the control facilities received ad hoc or no standardised skin-moisturising regimen. Participant numbers were sufficient to detect a 5% difference in incidence rate between the two groups with 80% power and a significance level of P = 0·05, and the inter-cluster correlation coefficient was 0·034. Data were collected over 6 months. A total of 1396 skin tears on 424 residents were recorded during the study. In the intervention group, the average monthly incidence rate was 5·76 per 1000 occupied bed days as compared to 10·57 in the control group. The application of moisturiser twice daily reduced the incidence of skin tears by almost 50% in residents living in aged care facilities.

  13. Effects of Intraseasonal Oscillation on the Anomalous East Asian Summer Monsoon During 1999

    Institute of Scientific and Technical Information of China (English)

    SUN Ying; DING Yihui

    2008-01-01

    The 1999 East Asian summer monsoon was very unusual for its weak northward advance and remarkably anomalous climate conditions.The monsoonal southwesterly airflow and related rain belt in East Asia were blocked south of the Yangtze River Valley.The monsoonal airflow and major moisture transport conduct shifted eastward and turned northward to Japan from the tropical western Pacific rather than to East China from the South China Sea(SCS)as in normal years.Severe and prolonged drought occurred over extensive areas of North China and heavy precipitation in South China and Japan.The investigation on the possible intrinsic mechanisms related to such an anomalous monsoon year has shown that the unique behavior of intraseasonal oscillation may play an essential role during this process.During this year,the northward propagation of 30-60-day anomalous low-level cyclone/anticyclone collapsed in the region around 20℃N and did not extend beyond the latitudes of the Yangtze River basin due to the barrier of strong cold air intrusion from the mid-latitudes.The southwesterly moisture flux on the northwestern flank of the anticyclonic moisture transport system in the western North Pacific,which was regulated by the northward shift of 30-60-day cyclonic/anticyclonic moisture transport.also did not reach the region north of 30℃N as well.Under this circumstance,the weak northward advance of the monsoon westerlies and associated northward moisture transport could not arrive in North China and led to the severe droughts there in 1999.The SCS and South China were mostly affected by the alrflow in the southern and northern flanks of the same 30-60-day cyclones or anticyclones.respectively,and thus controlled by the nearly reverse zonal wind and moisture convergent/divergent conditions.The rainfall in the SCS and South China showed out-of-phase oscillation through the transient local Hadley circulation.with the rainfall maximum occurring in the SCS (South China)when the 30-60-day

  14. Effect of olive and sunflower seed oil on the adult skin barrier: implications for neonatal skin care.

    Science.gov (United States)

    Danby, Simon G; AlEnezi, Tareq; Sultan, Amani; Lavender, Tina; Chittock, John; Brown, Kirsty; Cork, Michael J

    2013-01-01

    Natural oils are advocated and used throughout the world as part of neonatal skin care, but there is an absence of evidence to support this practice. The goal of the current study was to ascertain the effect of olive oil and sunflower seed oil on the biophysical properties of the skin. Nineteen adult volunteers with and without a history of atopic dermatitis were recruited into two randomized forearm-controlled mechanistic studies. The first cohort applied six drops of olive oil to one forearm twice daily for 5 weeks. The second cohort applied six drops of olive oil to one forearm and six drops of sunflower seed oil to the other twice daily for 4 weeks. The effect of the treatments was evaluated by determining stratum corneum integrity and cohesion, intercorneocyte cohesion, moisturization, skin-surface pH, and erythema. Topical application of olive oil for 4 weeks caused a significant reduction in stratum corneum integrity and induced mild erythema in volunteers with and without a history of atopic dermatitis. Sunflower seed oil preserved stratum corneum integrity, did not cause erythema, and improved hydration in the same volunteers. In contrast to sunflower seed oil, topical treatment with olive oil significantly damages the skin barrier, and therefore has the potential to promote the development of, and exacerbate existing, atopic dermatitis. The use of olive oil for the treatment of dry skin and infant massage should therefore be discouraged. These findings challenge the unfounded belief that all natural oils are beneficial for the skin and highlight the need for further research.

  15. Effect of olive and sunflower seed oil on the adult skin barrier: implications for neonatal skin care.

    Science.gov (United States)

    Danby, Simon G; AlEnezi, Tareq; Sultan, Amani; Lavender, Tina; Chittock, John; Brown, Kirsty; Cork, Michael J

    2013-01-01

    Natural oils are advocated and used throughout the world as part of neonatal skin care, but there is an absence of evidence to support this practice. The goal of the current study was to ascertain the effect of olive oil and sunflower seed oil on the biophysical properties of the skin. Nineteen adult volunteers with and without a history of atopic dermatitis were recruited into two randomized forearm-controlled mechanistic studies. The first cohort applied six drops of olive oil to one forearm twice daily for 5 weeks. The second cohort applied six drops of olive oil to one forearm and six drops of sunflower seed oil to the other twice daily for 4 weeks. The effect of the treatments was evaluated by determining stratum corneum integrity and cohesion, intercorneocyte cohesion, moisturization, skin-surface pH, and erythema. Topical application of olive oil for 4 weeks caused a significant reduction in stratum corneum integrity and induced mild erythema in volunteers with and without a history of atopic dermatitis. Sunflower seed oil preserved stratum corneum integrity, did not cause erythema, and improved hydration in the same volunteers. In contrast to sunflower seed oil, topical treatment with olive oil significantly damages the skin barrier, and therefore has the potential to promote the development of, and exacerbate existing, atopic dermatitis. The use of olive oil for the treatment of dry skin and infant massage should therefore be discouraged. These findings challenge the unfounded belief that all natural oils are beneficial for the skin and highlight the need for further research. PMID:22995032

  16. Skin tears.

    Science.gov (United States)

    Baranoski, S

    2001-08-01

    Skin tears are a serious, painful problem for older patients. Find out how your staff can recognize patients at risk, what they can do to prevent skin tears, and how to manage them effectively if they occur.

  17. Emerging magnetism and anomalous Hall effect in iridate–manganite heterostructures

    Science.gov (United States)

    Nichols, John; Gao, Xiang; Lee, Shinbuhm; Meyer, Tricia L.; Freeland, John W.; Lauter, Valeria; Yi, Di; Liu, Jian; Haskel, Daniel; Petrie, Jonathan R.; Guo, Er-Jia; Herklotz, Andreas; Lee, Dongkyu; Ward, Thomas Z.; Eres, Gyula; Fitzsimmons, Michael R.; Lee, Ho Nyung

    2016-01-01

    Strong Coulomb repulsion and spin–orbit coupling are known to give rise to exotic physical phenomena in transition metal oxides. Initial attempts to investigate systems, where both of these fundamental interactions are comparably strong, such as 3d and 5d complex oxide superlattices, have revealed properties that only slightly differ from the bulk ones of the constituent materials. Here we observe that the interfacial coupling between the 3d antiferromagnetic insulator SrMnO3 and the 5d paramagnetic metal SrIrO3 is enormously strong, yielding an anomalous Hall response as the result of charge transfer driven interfacial ferromagnetism. These findings show that low dimensional spin–orbit entangled 3d–5d interfaces provide an avenue to uncover technologically relevant physical phenomena unattainable in bulk materials. PMID:27596572

  18. When Chiral Photons Meet Chiral Fermions: Photoinduced Anomalous Hall Effects in Weyl Semimetals

    Science.gov (United States)

    Chan, Ching-Kit; Lee, Patrick A.; Burch, Kenneth S.; Han, Jung Hoon; Ran, Ying

    2016-01-01

    The Weyl semimetal is characterized by three-dimensional linear band touching points called Weyl nodes. These nodes come in pairs with opposite chiralities. We show that the coupling of circularly polarized photons with these chiral electrons generates a Hall conductivity without any applied magnetic field in the plane orthogonal to the light propagation. This phenomenon comes about because with all three Pauli matrices exhausted to form the three-dimensional linear dispersion, the Weyl nodes cannot be gapped. Rather, the net influence of chiral photons is to shift the positions of the Weyl nodes. Interestingly, the momentum shift is tightly correlated with the chirality of the node to produce a net anomalous Hall signal. Application of our proposal to the recently discovered TaAs family of Weyl semimetals leads to an order-of-magnitude estimate of the photoinduced Hall conductivity which is within the experimentally accessible range.

  19. Emerging magnetism and anomalous Hall effect in iridate-manganite heterostructures

    Science.gov (United States)

    Nichols, John; Gao, Xiang; Lee, Shinbuhm; Meyer, Tricia L.; Freeland, John W.; Lauter, Valeria; Yi, Di; Liu, Jian; Haskel, Daniel; Petrie, Jonathan R.; Guo, Er-Jia; Herklotz, Andreas; Lee, Dongkyu; Ward, Thomas Z.; Eres, Gyula; Fitzsimmons, Michael R.; Lee, Ho Nyung

    2016-09-01

    Strong Coulomb repulsion and spin-orbit coupling are known to give rise to exotic physical phenomena in transition metal oxides. Initial attempts to investigate systems, where both of these fundamental interactions are comparably strong, such as 3d and 5d complex oxide superlattices, have revealed properties that only slightly differ from the bulk ones of the constituent materials. Here we observe that the interfacial coupling between the 3d antiferromagnetic insulator SrMnO3 and the 5d paramagnetic metal SrIrO3 is enormously strong, yielding an anomalous Hall response as the result of charge transfer driven interfacial ferromagnetism. These findings show that low dimensional spin-orbit entangled 3d-5d interfaces provide an avenue to uncover technologically relevant physical phenomena unattainable in bulk materials.

  20. When Chiral Photons Meet Chiral Fermions: Photoinduced Anomalous Hall Effects in Weyl Semimetals.

    Science.gov (United States)

    Chan, Ching-Kit; Lee, Patrick A; Burch, Kenneth S; Han, Jung Hoon; Ran, Ying

    2016-01-15

    The Weyl semimetal is characterized by three-dimensional linear band touching points called Weyl nodes. These nodes come in pairs with opposite chiralities. We show that the coupling of circularly polarized photons with these chiral electrons generates a Hall conductivity without any applied magnetic field in the plane orthogonal to the light propagation. This phenomenon comes about because with all three Pauli matrices exhausted to form the three-dimensional linear dispersion, the Weyl nodes cannot be gapped. Rather, the net influence of chiral photons is to shift the positions of the Weyl nodes. Interestingly, the momentum shift is tightly correlated with the chirality of the node to produce a net anomalous Hall signal. Application of our proposal to the recently discovered TaAs family of Weyl semimetals leads to an order-of-magnitude estimate of the photoinduced Hall conductivity which is within the experimentally accessible range. PMID:26824561

  1. Hall effects on anomalous heat, particle and helicity transports through tearing-mode turbulence

    International Nuclear Information System (INIS)

    The helicity transport in a current-carrying plasma results in heat and particle transports in the direction opposite to the helicity flux. Tearing-mode turbulence produces helicity flux that is proportional to the gradient of equilibrium parallel current. The helicity flux is a consequence of a fluctuating electric field with a circularly polarized component, which also causes a nonlinear parallel current (primarily an electron flux) and a nonlinear polarization current (primarily an ion flux). Such anomalous heat and particle fluxes are driven by the free-energy associated with the perturbed magnetic field in the tearing-mode turbulence, and are typically directed inward to the plasma. Both fluxes becomes large when the gradient of the equilibrium current is large. 12 refs

  2. Transmission of phototherapy through human skin: dosimetry adjustment for effects of skin color, body composition, wavelength, and light coupling to skin

    Science.gov (United States)

    Nussbaum, Ethne L.; Van Zuylen, Jeff

    2006-02-01

    Purpose: To examine factors that affect penetration of phototherapy. Methods: Age, sex, height, and weight were recorded; skin color, skinfold thickness, and light transmission through a skinfold were measured over biceps and triceps muscles, and at the anterior waistline. Light was generated using two 23-diode LED arrays at 840 nm and 660 nm with surface area of 7 cm2. Photon irradiation was measured using an Optical Power Meter consisting of a 1x1-cm2 light detector placed in the centre of the illuminated 7 cm2 spot. Transmission was measured using three skin-diode coupling conditions. Results: Penetration of LED irradiation increased when diodes were coupled to skin with pressure. Red light attenuated more rapidly than infrared light and the attenuation of red light increased as skin color darkened. Penetration of red and infrared light decreased as the amount of subcutaneous fat increased. There were gender effects on penetration of infrared light at normal and low BMI values. Conclusions: When using divergent light sources for phototherapy, radiant exposure should take into account individual physical characteristics, irradiation wavelength and diode configuration of the laser therapy system.

  3. Skin Effect of Reversely Switched Dynistor in Short Pulse Discharge Application

    Institute of Scientific and Technical Information of China (English)

    Lin Liang; Yue-Hui Yu

    2009-01-01

    The skin effect in the reversely switched dynistor (RSD) devices is investigated in this paper. Based on the plasma bipolar drift model of the RSD, the current density distributions on the chip are simulated with considering the skin effect. The results indicate that the current density on the border can be several hundred to a thousand A/cm2 higher than that in the center of the chip. The skin effect becomes more prominent as the voltage increases and the inductance decreases in the main circuit. The phenomenon that most of a certain group of chips break over on the border has proved the existence of the skin effect.

  4. Development and validation of a tokamak skin effect transformer model

    Science.gov (United States)

    Romero, J. A.; Moret, J.-M.; Coda, S.; Felici, F.; Garrido, I.

    2012-02-01

    A lumped parameter, state space model for a tokamak transformer including the slow flux penetration in the plasma (skin effect transformer model) is presented. The model does not require detailed or explicit information about plasma profiles or geometry. Instead, this information is lumped in system variables, parameters and inputs. The model has an exact mathematical structure built from energy and flux conservation theorems, predicting the evolution and non-linear interaction of plasma current and internal inductance as functions of the primary coil currents, plasma resistance, non-inductive current drive and the loop voltage at a specific location inside the plasma (equilibrium loop voltage). Loop voltage profile in the plasma is substituted by a three-point discretization, and ordinary differential equations are used to predict the equilibrium loop voltage as a function of the boundary and resistive loop voltages. This provides a model for equilibrium loop voltage evolution, which is reminiscent of the skin effect. The order and parameters of this differential equation are determined empirically using system identification techniques. Fast plasma current modulation experiments with random binary signals have been conducted in the TCV tokamak to generate the required data for the analysis. Plasma current was modulated under ohmic conditions between 200 and 300 kA with 30 ms rise time, several times faster than its time constant L/R ≈ 200 ms. A second-order linear differential equation for equilibrium loop voltage is sufficient to describe the plasma current and internal inductance modulation with 70% and 38% fit parameters, respectively. The model explains the most salient features of the plasma current transients, such as the inverse correlation between plasma current ramp rates and internal inductance changes, without requiring detailed or explicit information about resistivity profiles. This proves that a lumped parameter modelling approach can be used to

  5. dermaOXY skin assay: effect and evidence

    DEFF Research Database (Denmark)

    Menov, Lasse; Klösgen-Buchkremer, Beate Maria

    2015-01-01

    of the instrument set DermaLab®Combo, which is used for the physical characterization of skin status after treatment. The report consists of four main parts, dedicated to 1. the properties of human skin 2. the anti-aging methods applied by the dermaOXY treatment 3. the analytical methods applied by derma...

  6. Anomalous effect in Schumann resonance phenomena observed in Japan, possibly associated with the Chi-chi earthquake in Taiwan

    Directory of Open Access Journals (Sweden)

    M. Hayakawa

    2005-06-01

    Full Text Available The Schumann resonance phenomenon has been monitored at Nakatsugawa (near Nagoya in Japan since the beginning of 1999, and due to the occurance of a severe earthquake (so-called Chi-chi earthquake on 21 September 1999 in Taiwan we have examined our Schumann resonance data at Nakatsugawa during the entire year of 1999. We have found a very anomalous effect in the Schumann resonance, possibly associated with two large land earthquakes (one is the Chi-chi earthquake and another one on 2 November 1999 (Chia-yi earthquake with a magnitude again greater than 6.0. Conspicuous effects are observed for the larger Chi-chi earthquake, so that we summarize the characteristics for this event. The anomaly is characterized mainly by the unusual increase in amplitude of the fourth Schumann resonance mode and a significant frequency shift of its peak frequency (~1.0Hz from the conventional value on the By magnetic field component which is sensitive to the waves propagating in the NS meridian plane. Anomalous Schumann resonance signals appeared from about one week to a few days before the main shock. Secondly, the goniometric estimation of the arrival angle of the anomalous signal is found to coincide with the Taiwan azimuth (the unresolved dual direction indicates toward South America. Also, the pulsed signals, such as the Q-bursts, were simultaneously observed with the "carrier" frequency around the peak frequency of the fourth Schumann resonance mode. The anomaly for the second event for the Chia-yi earthquake on 2 November had much in common. But, most likely due to a small magnitude, the anomaly appears one day before and lasts until one day after the main shock, with the enhancement at the fourth Schumann resonance mode being smaller in amplitude than the case of the Chi-chi earthquake. Yet, the other characteristics, including the goniometric direction finding result, frequency shift, etc., are nearly the same. Although the emphasis of

  7. Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol.

    Science.gov (United States)

    Muizzuddin, Neelam; Ingrassia, Michael; Marenus, Kenneth D; Maes, Daniel H; Mammone, Thomas

    2013-01-01

    Human skin maintains an optimal permeability barrier function in a terrestrial environment that varies considerably in humidity. Cells cultured under hyperosmotic stress accumulate osmolytes including sorbitol. Epidermal keratinocytes experience similar high osmolality under dry environmental conditions because of increased transepidermal water loss (TEWL) and concomitant drying of the skin. This study was designed to determine if epidermal keratinocytes, in vitro, could be protected from high osmotic stress, with the exogenous addition of sorbitol. In addition, we evaluated the effect of a formulation containing topical sorbitol on skin barrier and moisturization of subjects living in arid and humid regions in summer as well as in winter. Results from in vitro experiments showed that 50 mM sorbitol protected epidermal keratinocytes from osmotic toxicity induced by sodium chloride. Clinical studies indicated that skin chronically exposed to hot, dry environment appeared to exhibit stronger skin barrier and a lower baseline TEWL. In addition, skin barrier was stronger in summer than in winter. Sorbitol exhibited significant improvement in both barrier repair and moisturization, especially in individuals subjected to arid environmental conditions.

  8. Electron's anomalous magnetic moment effects on electron-hydrogen elastic collisions in the presence of a circularly polarized laser field

    CERN Document Server

    Elhandi, S; attaourti, Y; Manaut, B; Oufni, L

    2010-01-01

    The effect of the electron's anomalous magnetic moment on the relativistic electronic dressing for the process of electron-hydrogen atom elastic collisions is investigated. We consider a laser field with circular polarization and various electric field strengths. The Dirac-Volkov states taking into account this anomaly are used to describe the process in the first order of perturbation theory. The correlation between the terms coming from this anomaly and the electric field strength gives rise to new results, namely the strong dependence of the spinor part of the differential cross section (DCS) with respect to these terms. A detailed study has been devoted to the non relativistic regime as well as the moderate relativistic regime. Some aspects of this dependence as well as the dynamical behavior of the DCS in the relativistic regime have been addressed.

  9. Ferromagnetism, variable range hopping, and the anomalous Hall effect in epitaxial Co:ZnO thin film

    Institute of Scientific and Technical Information of China (English)

    Bai Hong-Liang; Chen Yan-Xue; Mei Liang-Mo; He Shu-Min; Xu Tong-Shuai; Liu Guo-Lei; Yan Shi-Shen; Zhu Da-Peng; Dai Zheng-Kun; Yang Feng-Fan; Dai You-Yong

    2012-01-01

    A series of high quality single crystalline epitaxial Zn0.95Co0.05O thin films is prepared by molecular beam epitaxy.Superparamagnetism and ferromagnetism are observed when the donor density is manipulated in a range of 1018 cm-3- 1020 cm-3 by changing the oxygen partial pressure during film growth.The conduction shows variable range hopping at low temperature and thermal activation conduction at high temperature.The ferromagnetism can be maintained up to room temperature.However,the anomalous Hall effect is observed only at low temperature and disappears above 160 K.This phenomenon can be attributed to the local ferromagnetism and the decreased optimal hopping distance at high temperatures.

  10. X-ray imaging and the skin: Radiation biology, patient dosimetry and observed effects

    International Nuclear Information System (INIS)

    A wide variety of radiation-induced deterministic skin effects have been observed after X-ray guided interventions ranging from mild effects, such as transient erythema or temporary epilation, to severe effects, such as desquamation and necrosis. Radiation biologists have identified, in addition to absorbed dose to the skin, other factors that strongly influence the type and severity of a skin reaction, including exposure-related factors (dose rate, fractionation, the size of the exposed area and its site), biological factors (age, oxygen status, capillary density, hormonal status and genetic factors) and ethnic differences. A peak entrance skin dose of 2 Gy is an arbitrary, but pragmatic, threshold for radiation-induced skin effects after X-ray guided interventions. Transient skin injury originating in the epidermis is not expected in the average patient population at peak entrance skin doses up to 6 Gy. Serious skin effects are not likely to occur in clinical practice when optimised X-ray equipment is used in combination with good techniques for fluoroscopy and imaging. However, this might not be true for patients with biological factors that are associated with an increased sensitivity for radiation-induced skin reactions. (authors)

  11. Micro-instabilities and anomalous transport effects in collisionless guide field reconnection

    Science.gov (United States)

    Munoz Sepulveda, Patricio Alejandro; Büchner, Jörg; Kilian, Patrick

    2016-07-01

    It is often the case that magnetic reconnection takes place in collisionless plasmas with a current aligned guide magnetic field, such as in the Solar corona. The general characteristics of this process have been exhaustively analyzed with theory and numerical simulations, under different approximations, since some time ago. However, some consequences and properties of the secondary instabilities arising spontaneously -other than tearing instability-, and their dependence on the guide field strength, have not been completely understood yet. For this sake, we use the results of fully kinetic 2D PIC numerical simulations of guide field reconnection. By using a mean field approach for the Generalized Ohm's law that explains the balance of the reconnected electric field, we find that some of the cross-streaming and gradient driven instabilities -in the guide field case- produce an additional anomalous transport term. The latter can be interpreted as a result of the enhanced correlated electromagnetic fluctuations, leading to a slow down of the current carriers and kinetic scale turbulence. We characterize these processes on dependence on the guide field strength, and explore the causal relation with the source of free energy driving the mentioned instabilities. Finally, we show the main consequences that a fully 3D approach have on all those phenomena in contrast to the reduced 2D description.

  12. Step-wise switching of anomalous Hall effect in a topological insulator

    Science.gov (United States)

    Zhao, Lukas; Chen, Zhiyi; Korzhovska, Inna; Zhao, Shihua; Krusin-Elbaum, Lia; Konczykowski, Marcin

    Surfaces of three-dimensional (3D) topological insulators (TIs) have emerged as one of the most remarkable states of condensed quantum matter where exotic charge and spin phases of Dirac particles could arise. The main challenge to finding these phases comes from a non-vanishing conductivity of the bulk. Recently we have demonstrated that we can access 2D surface transport and reach the charge neutrality point (CNP) by compensating intrinsically p-type TIs using high energy electron beams, and increase bulk resistivity by orders of magnitude. Here we report a discovery of anomalous Hall signal (AHE) at the CNP in Bi2Te3 of unprecedented appearance; it shows regions of plateaus on sweeping the temperature, where Hall resistivity is flat in temperature, and has sharp (nearly discontinuous) `steps' in-between the plateaus. The height of the steps increases on cooling, consistently following the ratio of 1:3 with each step. We will show by electrostatically tuning gated structures how this macroscopic switching of spins evolves in the vicinity of CNP and discuss the phenomenon of step-wise AHE in the context of charge inhomogeneities (puddles) and correlations between the localized bulk spins and Dirac spins. Supported by NSF-DMR-1420634, NSF-DMR-1312483-MWN, and DOD-W911NF-13-1-0159.

  13. Anomalous Hall effect in the Co-based Heusler compounds Co2FeSi and Co2FeAI

    Science.gov (United States)

    Imort, I.-M.; Thomas, P.; Reiss, G.; Thomas, A.

    2012-04-01

    The anomalous Hall effect (AHE) in the Heusler compounds Co2FeSi and Co2FeAl is studied in dependence of the annealing temperature to achieve a general comprehension of its origin. We have demonstrated that the crystal quality affected by annealing processes is a significant control parameter to tune the electrical resistivity ρxx as well as the anomalous Hall resistivity ρahe. Analyzing the scaling behavior of ρahe in terms of ρxx points to a temperature-dependent skew scattering as the dominant mechanism in both Heusler compounds.

  14. Effects of industrial detergents on the barrier function of human skin

    DEFF Research Database (Denmark)

    Nielsen, G D; Nielsen, Jesper Bo; Andersen, Klaus Ejner;

    2000-01-01

    Detergents are involved in the causation of contact dermatitis and in promoting percutaneous absorption of toxic chemicals, but limited information is available to allow an assessment of their relative effects on the skin barrier function. The effect of detergents on skin permeability to water an...

  15. Effect of microplasma irradiation on skin barrier function

    Science.gov (United States)

    Shimizu, Kazuo; Tran, An N.; Blajan, Marius

    2016-07-01

    In this paper, we introduce the feasibility of atmospheric-pressure argon microplasma irradiation (AAMI) to promote percutaneous absorption. A hairless Yucatan micropig skin was used for this ex vivo study. After AAMI, the disturbance in the stratum corneum (SC) lipids was observed using attenuated total reflectance-Fourier transform infrared spectroscopy. Also, an increase in transepidermal water loss and no physical damage on pig skins were confirmed by microscopic observation. These results of AAMI were compared with those of a plasma jet irradiation (PJI) and a tape stripping test (TST) leading to the conclusion that AAMI reduces the barrier function of the skin and could also enhance the transdermal absorption of drugs.

  16. Antioxidant effect of an ozonized theobroma oil formulation on damaged-inflammatory rat skin

    OpenAIRE

    Sánchez, Yaima; Maritza F. Díaz; Hernández, Frank; Gil, Dayana; García, Gastón

    2011-01-01

    The aim of this study was to determine whether a cosmetic formulation elaborated with ozonized theobroma oil may exert beneficial effects in the restoring of the antioxidant activity on the skin of rats previously irradiated with ultraviolet light. 0.5 g of the formulation was applied on the skin of rats for five days. Superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT) activity were determined in a homogenate of rat skin. Malondialdehyde (MDA), conjugated dienes (CD) ...

  17. Fractional Laser Photothermolysis in the Treatment of Skin Defects: Possibilities and Effectiveness (Review)

    OpenAIRE

    М.М. Karabut; N.D. Gladkova; F.I. Feldchtein

    2016-01-01

    For skin defect treatment and rejuvenation the ablative laser skin resurfacing with a CO2 laser is widely applied in cosmetology and dermatology. However this treatment can result in the risk of undesirable side effects and requires a long-term recovery after the procedure. When non-ablative laser skin rejuvenation is used as an alternative, the level of safety is increased, however the efficacy of the procedure is considerably reduced. The use of fractional laser photothermolysis is a partic...

  18. In vitro percutaneous absorption of chromium powder and the effect of skin cleanser.

    Science.gov (United States)

    Larese Filon, Francesca; D'Agostin, Flavia; Crosera, Matteo; Adami, Gianpiero; Bovenzi, Massimo; Maina, Giovanni

    2008-09-01

    The present study tried to investigate, using a synthetic sweat at pH 4.5, whether metallic chromium can pass through the skin (in vitro) and the effect of rapid skin decontamination with a common detergent. A suspension of chromium powder in synthetic sweat at pH 4.5 was prepared and shaken with a stirring plate at room temperature for 30 min. Human skin membranes were set up in Franz-diffusion cells and 1 ml of the freshly made suspension was applied to the outer surface of the skin for 24h. The tests were performed without and with decontamination using the cleanser 30 min after the start of exposure. The appearance of metal ions in the aqueous receptor phase was quantified by Electro Thermal Atomic Absorption Spectroscopy (ETAAS) and Inductively Coupled Plasma Atomic Emission Spectroscopy (ICP-AES). Speciation analysis and measurements of chromium skin content were also performed. Chromium skin permeation was demonstrated in in vitro experiments using the Franz cell system, giving a permeation flux of 0.84+/-0.25 ng cm(-2)h(-1) and a lag time of 1.1+/-0.7h. The cleaning procedure stop Cr permeation but its concentration into the skin significantly increased (Mann-Whitney U test P<0.03). The results revealed that chromium applied as powder can pass through the skin and that decontamination, done after 30 min of exposure, prevent Cr skin permeation but increase Cr content into the skin.

  19. [In vitro percutaneous absorption of chromium powder and the effect of skin cleanser].

    Science.gov (United States)

    D'Agostin, F; Crosera, M; Adami, G; Malvestio, A; Rosani, R; Bovenzi, M; Maina, G; Filon, F Larese

    2007-01-01

    Occupational chromium dermatitis occurs frequently among cement and metal workers, workers dealing with leather tanning and employees in the ceramic industry. The present study, using an in-vitro system, evaluated percutaneous absorption of chromium powder and the effect of rapid skin decontamination with a common detergent. Experiments were performed using the Franz diffusion cell method with human skin. Physiological solution was used as receiving phase and a suspension of chromium powder in synthetic sweat was used as donor phase. The tests were performed without or with decontamination using the cleanser 30 minutes after the start of exposure. The amount of chromium permeated through the skin was analysed by Inductively Coupled Plasma Atomic Emission Spectroscopy and Electro Thermal Atomic Absorption Spectroscopy. Speciation analysis and measurements of chromium skin content were also performed. We calculated a permeation flux of 0.843 +/- 0.25 ng cm(-2) h(-1) and a lag time of 1.1 +/- 0.7 h. The cleaning procedure significantly increased chromium skin content, whereas skin passage was not increased. These results showed that chromium powder can pass through the skin and that skin decontamination did not decrease skin absorption. Therefore, it is necessary to prevent skin contamination when using toxic agents.

  20. Effects of hair removal alexandrite laser on biometric parameters of the skin.

    Science.gov (United States)

    Alavi, Shiva; Abolhasani, Ehsan; Nilforoushzadeh, Mohammadali

    2016-04-01

    The effects of alexandrite laser (AL) on skin parameters such as melanin content, skin layer depth, elasticity, and density have not been investigated through biometric methods. We aim to assess the effect of AL on the skin parameters through biometric devices to determine whether it has positive effects on treated region. In this pretest-posttest study, we recruited patients who attended Laser Clinic of Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran, from January through December 2014. Patients had to be free of any dermatologic conditions and lesion at the site of treatment or any contraindication to laser therapy. Baseline measurements were performed and patients received four sessions of AL therapy (spot size, 12 mm; fluence, 12 J/cm(2); and pulse width, 5 Hz) with 4-week intervals. Four weeks after the last treatment session, the same parameters were assessed that included skin color, transepidermal water loss (TEWL), dermis and epidermis density and depth (through skin ultrasonography), melanin content, erythema intensity, and skin elasticity. Biometric parameters of 33 patients (27 females [81.8%]), with mean (SD) age of 35.7 (9.5) years were evaluated. The mean percent changes of skin parameters were as follows: skin color, 5.88% through Visioface and by 56.8% through Colorimeter devices (became lighter); melanin content, -15.95%; TEWL, -2.96%; elasticity, +14.88%; dermis depth -19.01%; and dermis density, +1580.11% (P melanin content of the skin and make the skin thinner while it could increase elasticity and density of epidermis and dermis, which might indicate increased collagen content of skin. PMID:26861986

  1. Clinical effects of an oral supplement rich in antioxidants on skin radiance in women

    Science.gov (United States)

    Dumoulin, Marion; Gaudout, David; Lemaire, Benoit

    2016-01-01

    Background Environmental factors impact the skin aging resulting in decrease of skin radiance. Nutrition and particularly antioxidants could help to fight against skin degradation. Objective The aim of this study was to evaluate the effects of an oral supplement rich in specific antioxidants, SkinAx2TM, on the improvement of the skin radiance in women. Methods The open-label clinical study enrolled 35 women, aged 40–70, with facial dull complexion. Subjects were supplemented orally with a daily dosage of 150 mg of an antioxidant-rich formulation containing superoxide dismutase-rich melon concentrate, grape seed extract rich in monomers of flavanols, vitamin C, and zinc for 8 weeks. Each subject served as her own control. The C.L.B.T.™ test has been used to evaluate facial skin coloring (C), luminosity (L), brightness (B), and transparency (T) involved in skin radiance. Facial skin imperfections have been assessed by clinical assessment. Firmness has been evaluated by clinical assessment and cutometer measurement. Finally, an auto-questionnaire has been carried out in order to evaluate the satisfaction of the subjects concerning different parameters involved in skin radiance and the global efficacy of the supplement. Results Skin “red pink” and “olive” colors were significantly improved after supplementation (Pskin imperfections were significantly reduced after the antioxidant-rich formulation intake (global reduction: −18.0%; Pskin. Furthermore, 64.7% reported to look better at the end of the supplementation. Conclusion The oral supplement containing the antioxidant-rich formulation was found to improve skin radiance by reducing skin coloring, increasing face luminosity, reducing imperfections, and improving skin firmness in women with dull complexion. PMID:27799805

  2. Proinflammatory Effects of Diesel Exhaust Nanoparticles on Scleroderma Skin Cells

    Directory of Open Access Journals (Sweden)

    A. Mastrofrancesco

    2014-01-01

    Full Text Available Autoimmune diseases are complex disorders of unknown etiology thought to result from interactions between genetic and environmental factors. We aimed to verify whether environmental pollution from diesel engine exhaust nanoparticulate (DEP of actually operating vehicles could play a role in the development of a rare immune-mediated disease, systemic sclerosis (SSc, in which the pathogenetic role of environment has been highlighted. The effects of carbon-based nanoparticulate collected at the exhaust of newer (Euro 5 and older (Euro 4 diesel engines on SSc skin keratinocytes and fibroblasts were evaluated in vitro by assessing the mRNA expression of inflammatory cytokines (IL-1α, IL-6, IL-8, and TNF-α and fibroblast chemical mediators (metalloproteases 2, 3, 7, 9, and 12; collagen types I and III; VEGF. DEP was shown to stimulate cytokine gene expression at a higher extent in SSc keratinocytes versus normal cells. Moreover, the mRNA gene expression of all MMPs, collagen types, and VEGF genes was significantly higher in untreated SSc fibroblasts versus controls. Euro 5 particle exposure increased the mRNA expression of MMP-2, -7, and -9 in SSc fibroblasts in a dose dependent manner and only at the highest concentration in normal cells. We suggest that environmental DEP could trigger the development of SSc acting on genetically hyperreactive cell systems.

  3. Effect of chicken skin on the quality characteristics of semi-dried restructured jerky.

    Science.gov (United States)

    Choi, Yun-Sang; Han, Doo-Jeong; Choi, Ji-Hun; Hwang, Ko-Eun; Song, Dong-Heon; Kim, Hyun-Wook; Kim, Young-Boong; Kim, Cheon-Jei

    2016-05-01

    The objective of this study was to evaluate the effect of skin on the textural properties of semi-dried jerky produced with different acid treatments. Jerky was prepared with no skin (control) or with 1, 3, or 5% chicken skin. After hand mixing (for 3 min) and tumbling (for 30 min) to distribute the curing ingredients, the cured meats were dried for 180 min at 55°C, for 180 min at 65°C, and finally for 60 min at 75°C. The presence of skin was shown to result in a higher fat content, TBA value, and metmyoglobin due to the high fat content of the skin. In contrast, acid treatment decreased the TBA value and metmyoglobin in jerky relative to samples that were not subjected to acid treatment. The presence of skin also improved the moisture contents, processing yields, and mechanical tenderness.

  4. Spontaneous anomalous and spin Hall effects due to spin-orbit scattering of evanescent wave functions in magnetic tunnel junctions.

    Science.gov (United States)

    Vedyayev, A; Ryzhanova, N; Strelkov, N; Dieny, B

    2013-06-14

    We theoretically investigated the anomalous Hall effect (AHE) and spin Hall effect (SHE) transversal to the insulating spacer I, in magnetic tunnel junctions of the form F/I/F where the F's are ferromagnetic layers and I represents a tunnel barrier. We considered the case of purely ballistic (quantum mechanical) transport. These effects arise because of the asymmetric scattering of evanescent wave functions due to the spin-orbit interaction in the tunnel barrier. The AHE and SHE we investigated have a surface nature due to the proximity effect. Their amplitude is of first order in the scattering potential. This contrasts with ferromagnetic metals wherein these effects are of second (side-jump scattering) and third (skew scattering) order in these potentials. The value of the AHE current in the insulating spacer may be much larger than that in metallic ferromagnetic electrodes. For the antiparallel orientation of the magnetizations in the two F electrodes, a spontaneous Hall current exists even at zero applied voltage. PMID:25165958

  5. The role of the skin barrier in modulating the effects of common skin microbial species on the inflammation, differentiation and proliferation status of epidermal keratinocytes

    OpenAIRE

    Duckney, Patrick; Wong, Heng Kuan; Serrano, José; Yaradou, Diaraf; Oddos, Thierry; Georgios N. Stamatas

    2013-01-01

    Background Skin resident microbial species are often thought of either as pathogenic or commensal. However, little is known about the role of the skin barrier in modulating their potential for causing disease. To investigate this question we measured the effects of three microbial species commonly found on the skin (Staphylococcus epidermidis, Staphylococcus aureus, and Propionibacterium acnes) on a reconstructed human epidermal model by either applying the bacteria on the model surface (inta...

  6. The immune stimulatory effect of cyanacrylate skin surface stripping on the activation and migration of langerhans cells in human skin in vitro and in vivo

    OpenAIRE

    Deckert, Iliane

    2010-01-01

    Transcutanous immunization (TCI) is a promising alternative to conventional injections, because in contrast to muscle and fat tissue, the skin is especially rich in antigen-presenting cells, e.g. Langerhans cells (LC). Different techniques have been proposed to overcome the barrier function of the skin. Recently, a newly developed protocol based on cyanoacrylate skin surface stripping (CSSS), which facilitates penetration via hair follicles, has been shown to be safe and effective in inducing...

  7. The effect of skin temperature on performance during a 7.5-km cycling time trial

    NARCIS (Netherlands)

    Levels, K.; Koning, J.J. de; Foster, C.; Daanen, H.A.M.

    2012-01-01

    Aerobic exercise performance is seriously compromised in the heat. Possibly, a high skin temperature causes a rating of perceived exertion (RPE)-mediated decrease in exercise intensity. The purpose of this study was to determine the effect of skin temperature on power output during a 7.5-km cycling

  8. Suppressing the neoclassical tearing modes in tokamaks during anomalous transverse transport owing to predomination of the magnetic well effect over the bootstrap drive

    International Nuclear Information System (INIS)

    Suppression of neoclassical tearing modes in tokamaks under anomalous transverse transport conditions when the magnetic well effect predominates over the bootstrap drive is studied. Reduced equations of transfer are used in the description. Geodetic effects are considered during the magnetic well calculation. A criterion for the stabilization of neoclassical tearing modes by the compound effect at an arbitrary level of the transverse heat transport by electrons and ions is derived

  9. Effectiveness of an employee skin cancer screening program for secondary prevention.

    Science.gov (United States)

    Uslu, Ugur; Hees, Felix; Winnik, Eva; Uter, Wolfgang; Sticherling, Michael

    2016-08-01

    Incidences of UV-induced skin cancer are continuously increasing. For this reason, early diagnosis is becoming more important. In this study, 783 employees of a technical company participated in an employee skin cancer screening program, which consisted of a physical examination for benign and malignant skin lesions and premalignant conditions. To ensure the quality of the examinations, screening was only performed by 5 trained dermatologists. Participants also were asked to complete a standardized questionnaire prior to examination. A total of 661 skin lesions were diagnosed among 48% of participants; 12.8% of participants exhibited 50 or more melanocytic nevi and the risk for developing skin cancer was categorized as at least moderate for 64.9%. Additionally, 84.4% of participants with at least 1 skin lesion were advised to have a checkup within 1 year. The high rate of suspicious nevi detected in this study suggested that employee skin cancer screening programs are effective and also should be recommended at companies where employees are not at increased risk for developing skin cancer due to the nature of their work (eg, those who work outdoors). Despite the comparatively selective and young study population, these examinations provide evidence of the importance of skin cancer screening for the wider population. PMID:27622254

  10. Quantum anomalous Hall effect and a nontrivial spin-texture in ultra-thin films of magnetic topological insulators

    Energy Technology Data Exchange (ETDEWEB)

    Duong, Le Quy; Das, Tanmoy; Feng, Y. P.; Lin, Hsin, E-mail: nilnish@gmail.com [Graphene Research Centre and Department of Physics, National University of Singapore, Singapore 117546 (Singapore)

    2015-05-07

    We study the evolution of quantum anomalous Hall (QAH) effect for a Z{sub 2} topological insulator (TI) thin films in a proximity induced magnetic phase by a realistic layered k·p model with interlayer coupling. We examine three different magnetic configurations in which ferromagnetic (FM) layer(s) is added either from one side (FM-TI), from both sides (FM-TI-FM), or homogeneously distributed (magnetically doped) in a TI slab. We map out the thickness-dependent topological phase diagram under various experimental conditions. The critical magnetic exchange energy for the emergence of QAH effect in the latter two cases decreases monotonically with increasing number of quintuple layers (QLs), while it becomes surprisingly independent of the film thickness in the former case. The gap size of the emergent QAH insulator depends on the non-magnetic “parent” gap of the TI thin film and is tuned by the FM exchange energy, opening a versatile possibility to achieve room-temperature QAH insulator in various topological nanomaterials. Finally, we find that the emergent spin-texture in the QAH effect is very unconventional, non-“hedgehog” type; and it exhibits a chiral out-of-plane spin-flip texture within the same valence band which is reminiscent of dynamical “skyrmion” pattern, except our results are in the momentum space.

  11. Novel Inhibitory Effect of N-(2-Hydroxycyclohexylvaliolamine on Melanin Production in a Human Skin Model

    Directory of Open Access Journals (Sweden)

    Bum-Ho Bin

    2014-07-01

    Full Text Available Hyper-pigmentation causes skin darkness and medical disorders, such as post-inflammatory melanoderma and melasma. Therefore, the development of anti-melanogenic agents is important for treating these conditions and for cosmetic production. In our previous paper, we demonstrated that the anti-diabetic drug voglibose, a valiolamine derivative, is a potent anti-melanogenic agent. In addition, we proposed an alternative screening strategy to identify valiolamine derivatives with high skin permeability that act as anti-melanogenic agents when applied topically. In this study, we synthesized several valiolamine derivatives with enhanced lipophilicity and examined their inhibitory effects in a human skin model. N-(2-hydroxycyclohexylvaliolamine (HV possesses a stronger inhibitory effect on melanin production than voglibose in a human skin model, suggesting that HV is a more potent anti-melanogenic agent for the skin.

  12. Electrical measurement of moisturizing effect on skin hydration and barrier function in psoriasis patients.

    Science.gov (United States)

    Rim, J H; Jo, S J; Park, J Y; Park, B D; Youn, J I

    2005-07-01

    Transepidermal water loss (TEWL) in psoriatic skin lesions seems to be related to the severity of the psoriasis, and the electrical capacitance and conductance of the skin are indicators of the hydration level of the stratum corneum. We compared the characteristics of these electrical measurements, in assessing the persistent effect of a moisturizing cream on skin hydration and barrier function in psoriasis patients. Seventeen Korean psoriasis patients were recruited. Their right leg was treated with the moisturizer twice daily for 6 weeks, while their left leg was used as the control site. For each patient, one psoriatic plaque on each leg was selected as the involved psoriatic lesion. Uninvolved psoriatic skin was regarded as the apparently healthy looking skin 4-5 cm away from the periphery of the psoriatic lesion. The TEWL, electrical capacitance and conductance were measured, in order to evaluate the barrier function and hydration level of the stratum corneum. The clinical and biophysical data for each patient were recorded at the start of the study and after 2, 4 and 6 weeks. The degree of skin dryness at the applied area improved progressively. The electrical capacitance at the treated psoriatic lesion increased significantly after 2 weeks, and this improvement was maintained during the entire study period. However, no noticeable change was observed in the electrical conductance. The TEWL showed an inverse pattern to that of the skin capacitance, decreasing during the study period. The skin capacitance and TEWL exhibited good correlation with the visual assessment of skin dryness, but the skin conductance did not. Our data suggest that electrical capacitance and TEWL may be useful in the evaluation of the effect of a moisturizer on the hydration status and barrier function of psoriatic skin. PMID:15953083

  13. The effects of mucopolysaccharide polysulphate on hydration and elasticity of human skin.

    Science.gov (United States)

    Wanitphakdeedecha, Rungsima; Eimpunth, Sasima; Manuskiatti, Woraphong

    2011-01-01

    Background. Mucopolysaccharide polysulphate (MPS) has been used in medicine as an anti-inflammatory and antithrombotic agent for over 50 years. Its chemical structure permits considerable hydrogen bonding with adjacent water molecules, which effectively leads to hydration of the surrounding tissue. In addition, it stimulates endogenous hyaluronate synthesis, resulting in an increase in water-binding capacity and viscoelasticity of the skin. Objective. To study the efficacy of 0.1% MPS on hydration and elasticity of human skin. Methods. The first part of this study was a randomized double blind placebo-controlled study which included 60 female volunteers aged 30-45 years with dry skin, defined by Corneometer CM 825. The volunteers were treated with either 0.1% MPS or vehicle control. All subjects were asked to apply 1 g of cream to their face twice daily for a total period of 4 weeks. Skin hydration and elasticity were measured at baseline and week 4 with Corneometer CM 825 and cutometer MPA 580, respectively, at forehead and both cheeks. The second part of this study focused on the efficacy of 0.1% MPS on skin hydration after single application. 20 female volunteers aged 30-45 years with dry skin, defined by Corneometer CM 825, were recruited to the study. All subjects were asked to apply 2 g of 0.1% MPS cream on entirely randomly selected forearm. Skin hydration at the middle of both forearms was measured at baseline, immediately after application, and every 1 hour after application for a period of 10 hours. Results. 57 subjects (28 in vehicle control group, 29 in MPS) completed treatment protocol. The baseline skin hydration of both groups was not significantly different (P = 0.47). Hower, there was a statistically significant difference in skin hydration at 4 weeks between MPS and placebo group (P = 0.01). Skin elasticity was significantly improved at week 4 in both groups (vehicle-control, P < 0.01, and MPS, P < 0.01). However, no significant

  14. Clinical effects of an oral supplement rich in antioxidants on skin radiance in women

    Directory of Open Access Journals (Sweden)

    Dumoulin M

    2016-10-01

    Full Text Available Marion Dumoulin, David Gaudout, Benoit Lemaire Activ’Inside, Libourne, France Background: Environmental factors impact the skin aging resulting in decrease of skin radiance. Nutrition and particularly antioxidants could help to fight against skin degradation.Objective: The aim of this study was to evaluate the effects of an oral supplement rich in specific antioxidants, SkinAx2TM, on the improvement of the skin radiance in women.Methods: The open-label clinical study enrolled 35 women, aged 40–70, with facial dull complexion. Subjects were supplemented orally with a daily dosage of 150 mg of an antioxidant-rich formulation containing superoxide dismutase-rich melon concentrate, grape seed extract rich in monomers of flavanols, vitamin C, and zinc for 8 weeks. Each subject served as her own control. The C.L.B.T.™ test has been used to evaluate facial skin coloring (C, luminosity (L, brightness (B, and transparency (T involved in skin radiance. Facial skin imperfections have been assessed by clinical assessment. Firmness has been evaluated by clinical assessment and cutometer measurement. Finally, an auto-questionnaire has been carried out in order to evaluate the satisfaction of the subjects concerning different parameters involved in skin radiance and the global efficacy of the supplement.Results: Skin “red pink” and “olive” colors were significantly improved after supplementation (P<0.0001. Luminosity was increased by 25.9% (P<0.0001 whereas brightness and transparency were not affected by the supplementation. Facial skin imperfections were significantly reduced after the antioxidant-rich formulation intake (global reduction: –18.0%; P<0.0001. Indeed, dark circles, redness, and spots significantly diminished after oral treatment. Firmness and elasticity have been shown to be improved. Subjects were globally satisfied by the product (82.4% and have found improvements on their facial skin. Furthermore, 64.7% reported to look

  15. The Effects of Mucopolysaccharide Polysulphate on Hydration and Elasticity of Human Skin

    Directory of Open Access Journals (Sweden)

    Rungsima Wanitphakdeedecha

    2011-01-01

    Full Text Available Background. Mucopolysaccharide polysulphate (MPS has been used in medicine as an anti-inflammatory and antithrombotic agent for over 50 years. Its chemical structure permits considerable hydrogen bonding with adjacent water molecules, which effectively leads to hydration of the surrounding tissue. In addition, it stimulates endogenous hyaluronate synthesis, resulting in an increase in water-binding capacity and viscoelasticity of the skin. Objective. To study the efficacy of 0.1% MPS on hydration and elasticity of human skin. Methods. The first part of this study was a randomized double blind placebo-controlled study which included 60 female volunteers aged 30–45 years with dry skin, defined by Corneometer CM 825. The volunteers were treated with either 0.1% MPS or vehicle control. All subjects were asked to apply 1 g of cream to their face twice daily for a total period of 4 weeks. Skin hydration and elasticity were measured at baseline and week 4 with Corneometer CM 825 and cutometer MPA 580, respectively, at forehead and both cheeks. The second part of this study focused on the efficacy of 0.1% MPS on skin hydration after single application. 20 female volunteers aged 30–45 years with dry skin, defined by Corneometer CM 825, were recruited to the study. All subjects were asked to apply 2 g of 0.1% MPS cream on entirely randomly selected forearm. Skin hydration at the middle of both forearms was measured at baseline, immediately after application, and every 1 hour after application for a period of 10 hours. Results. 57 subjects (28 in vehicle control group, 29 in MPS completed treatment protocol. The baseline skin hydration of both groups was not significantly different (P=0.47. Hower, there was a statistically significant difference in skin hydration at 4 weeks between MPS and placebo group (P=0.01. Skin elasticity was significantly improved at week 4 in both groups (vehicle-control, P<0.01, and MPS, P<0.01. However, no

  16. The inverse skin effect in the Z-pinch and plasma focus

    Science.gov (United States)

    Usenko, P. L.; Gaganov, V. V.

    2016-08-01

    The inverse skin effect and its influence on the dynamics of high-current Z-pinch and plasma focus discharges in deuterium are analyzed. It is shown that the second compression responsible for the major fraction of the neutron yield can be interpreted as a result of the inverse skin effect resulting in the axial concentration of the longitudinal current density and the appearance of a reversed current in the outer layers of plasma pinches. Possible conditions leading to the enhancement of the inverse skin effect and accessible for experimental verification by modern diagnostics are formulated.

  17. Effect of lipopolysaccharide on the biological characteristics of human skin fibroblasts and hypertrophic scar tissue formation.

    Science.gov (United States)

    Yang, Hongming; Hu, Chao; Li, Fengyu; Liang, Liming; Liu, Lingying

    2013-06-01

    Burn injury-mediated destruction of the skin barrier normally induces microbial invasion, in turn leading to the development of systemic infection and occasional septic shock by the release of endotoxins. The objective of this work was to study the influence of lipopolysaccharide (LPS) on the biological characteristics of normal skin fibroblasts and to elucidate the influence of LPS in the initial stage of skin wound healing. Twenty patients with hypertrophic scar in proliferative stage were selected randomly and primary cultures were established from fibroblasts derived from their hypertrophic scar tissue and normal skin. Normal skin fibroblasts of passage 3 were stimulated with different concentrations of LPS. LPS stimulated the proliferation and collagen synthesis of fibroblasts within a certain extent of concentrations (0.005-0.5 μg/mL) (P effect on normal skin fibroblasts-continuous passage of these fibroblasts resulted in ultrastructural pattern similar to fibroblasts derived from hypertrophic scar tissue, and the findings was substantiated by hematoxylin and eosin staining and immunohistochemistry detection of proliferation cell nuclear antigen, type I procollagen and α-smooth muscle actin. Our results suggest that LPS might convert normal skin fibroblasts to hypertrophic scar tissue fibroblasts and participate in the formation of hypertrophic scar; hence, appropriate concentration of LPS may have no effect or be beneficial to skin wound healing, whereas excessive concentration of LPS may delay the time of wound healing. PMID:23653386

  18. The moisturizing effects of glycolipid biosurfactants, mannosylerythritol lipids, on human skin.

    Science.gov (United States)

    Yamamoto, Shuhei; Morita, Tomotake; Fukuoka, Tokuma; Imura, Tomohiro; Yanagidani, Shusaku; Sogabe, Atsushi; Kitamoto, Dai; Kitagawa, Masaru

    2012-01-01

    Glycolipid biosurfactants, such as mannosylerythritol lipids (MELs), are produced by different yeasts belonging to the genus Pseudozyma and have been attracting much attention as new cosmetic ingredients owing to their unique liquid-crystal-forming and moisturizing properties. In this study, the effects of different MEL derivatives on the skin were evaluated in detail using a three-dimensional cultured human skin model and an in vivo human study. The skin cells were cultured and treated with sodium dodecyl sulfate (SDS), and the effects of different lipids on the SDS-damaged cells were evaluated on the basis of cell viability. Most MEL derivatives efficiently recovered the viability of the cells and showed high recovery rates (over 80%) comparable with that of natural ceramide. It is interesting that the recovery rate with MEL-A prepared from olive oil was significantly higher than that of MEL-A prepared from soybean oil. The water retention properties of MEL-B were further investigated on human forearm skin in a preliminary study. Compared with the control, the aqueous solution of MEL-B (5 wt%) was estimated to considerably increase the stratum corneum water content in the skin. Moreover, perspiration on the skin surface was clearly suppressed by treatment with the MEL-B solution. These results suggest that MELs are likely to exhibit a high moisturizing action, by assisting the barrier function of the skin. Accordingly, the yeast glycolipids have a strong potential as a new ingredient for skin care products. PMID:22790172

  19. Experimental investigation of system effects in stressed-skin elements

    DEFF Research Database (Denmark)

    Dela Stang, B.; Isaksson, T.; Hansson, M.

    What kind of behaviour can be expected from stressed-skin elements at failure? To answer this question was a primary objective of the experimental investigation presented in this report. Systems of 3 roof units, each made of 5 parallel beams, have been tested for load-carrying capacity...

  20. Landau Damping and Anomalous Skin Effect in Low-pressure Gas Discharges: Self-consistent Treatment of Collisionless Heating

    Energy Technology Data Exchange (ETDEWEB)

    Igor D. Kaganovich; Oleg V. Polomarov; Constantine E. Theodosiou

    2004-01-30

    In low-pressure discharges, where the electron mean free path is larger or comparable with the discharge length, the electron dynamics is essentially nonlocal. Moreover, the electron energy distribution function (EEDF) deviates considerably from a Maxwellian. Therefore, an accurate kinetic description of the low-pressure discharges requires knowledge of the nonlocal conductivity operator and calculation of the non-Maxwellian EEDF. The previous treatments made use of simplifying assumptions: a uniform density profile and a Maxwellian EEDF. In the present study a self-consistent system of equations for the kinetic description of nonlocal, nonuniform, nearly collisionless plasmas of low-pressure discharges is reported. It consists of the nonlocal conductivity operator and the averaged kinetic equation for calculation of the non-Maxwellian EEDF. This system was applied to the calculation of collisionless heating in capacitively and inductively coupled plasmas. In particular, the importance of accounting for the nonuniform plasma density profile for computing the current density profile and the EEDF is demonstrated. The enhancement of collisionless heating due to the bounce resonance between the electron motion in the potential well and the external radio-frequency electric field is investigated. It is shown that a nonlinear and self-consistent treatment is necessary for the correct description of collisionless heating.

  1. Anomalous Hall effect suppression in anatase Co:TiO2 by the insertion of an interfacial TiO2 buffer layer

    NARCIS (Netherlands)

    Lee, Y.J.; Jong, de M.P.; Wiel, van der W.G.; Kim, Y.; Brock, J.D.

    2010-01-01

    We present the effect of introducing a TiO2 buffer layer at the SrTiO3/Co:TiO2 interface on the magnetic and structural properties of anatase Co:TiO2 (1.4 at. % Co). Inserting the buffer layer leads to suppression of the room-temperature anomalous Hall effect, accompanied by a reduced density of Co

  2. Anomalous enhancement and suppression of ionization induced by an effective few-cycle pulse in the frequency domain

    Science.gov (United States)

    Foote, David; Lin, Yingda; Hill, Wendell T., III

    2015-05-01

    In a recent set of coherent control experiments, an anomalous sinusoidal variation of the ionization yield was observed in Xe when ionized by a pairs of phase-locked, many-cycle 800 nm pulses. Compared with the signal of a single transform limited pulse, both enhancement and suppression was possible, which depended on the temporal separation and relative phase of the pulses. In the time domain, the control can be viewed as a temporal Young's double slit experiment - two coherent electron wavepackets interfering. In the frequency domain, the photoelectron spectrum is given by the modulus squared of the Fourier transform of the field, which is a few-cycle squared sinusodial function. In analogy to a few-cycle pulse where the carrier phase dictates the ejection direction of rescattered electrons, enhancement (suppression) occurs when the effective carrier waveform is cos[w-w0]2 (sin[w-w0]2). The contrast decreased with increasing pulse separation and decreasing multiphoton order. Detailed results and a model simulation will be presented.

  3. Theory of the Dirac half metal and quantum anomalous Hall effect in Mn-intercalated epitaxial graphene

    Science.gov (United States)

    Li, Yuanchang; West, Damien; Huang, Huaqing; Li, Jia; Zhang, S. B.; Duan, Wenhui

    2015-11-01

    The prospect of a Dirac half metal, a material which is characterized by a band structure with a gap in one spin channel but a Dirac cone in the other, is of both fundamental interest and a natural candidate for use in spin-polarized current applications. However, while the possibility of such a material has been reported based on model calculations [H. Ishizuka and Y. Motome, Phys. Rev. Lett. 109, 237207 (2012), 10.1103/PhysRevLett.109.237207], it remains unclear what material system might realize such an exotic state. Using first-principles calculations, we show that the experimentally accessible Mn-intercalated epitaxial graphene on SiC(0001) transits to a Dirac half metal when the coverage is >1 /3 monolayer. This transition results from an orbital-selective breaking of quasi-two-dimensional inversion symmetry, leading to symmetry breaking in a single spin channel which is robust against randomness in the distribution of Mn intercalates. Furthermore, the inclusion of spin-orbit interaction naturally drives the system into the quantum anomalous Hall (QAH) state. Our results thus not only demonstrate the practicality of realizing the Dirac half metal beyond a toy model, but also open up an avenue to the realization of the QAH effect.

  4. Photo- and gas-tuned, reversible thermoelectric properties and anomalous photo-thermoelectric effects of platinum-loaded tungsten trioxide

    Science.gov (United States)

    Suzuki, Kenta; Watanabe, Takuya; Kakemoto, Hirofumi; Irie, Hiroshi

    2016-06-01

    We report the photo- and gas-controllable properties of platinum-loaded tungsten trioxide (Pt/WO3), which is of interest for developing practical applications of WO3 as well as for interpreting such phenomena from scientific viewpoints. Here, a Pt/WO3 thin film generated a thermoelectric power due to the ultraviolet-light-induced band-gap excitation (photochromic (PC) reaction) and/or dark storage in formic acid vapor (gaschromic (GC) reaction) in the absence of O2, resulting from the generation of W5+ ions. After such chromic reactions, the electrical conductivity (σ) is increased, whereas the absolute value of the Seebeck coefficient (S) is decreased. The changes in σ and S and their rate of change for consistency increased in the order of: during the PC reaction extracted from the W5+ state, decreasing the number of W5+ in HxWO3 and thus contributing to the increase in Sphoto. After light irradiation, the accumulated electrons in Pt are returned to the energetically favorable W5+ state, and Pt/HxWO3 are returned to the initial state. Then both σ and S are decreased. The mechanisms of our anomalous, nontrivial photo-thermoelectric effects are presumed to be different from that involving the two-carrier contribution to the transport properties.

  5. Observation and modeling of anomalous CN polarization profiles produced by the molecular Paschen-Back effect in sunspots

    CERN Document Server

    Ramos, A A; Collados, M

    2005-01-01

    We report novel spectropolarimetric observations of sunspots carried out with the Tenerife Infrared Polarimeter (TIP) in a near-IR spectral region around 15410 A, which is known to contain two groups of prominent OH lines that show circular polarization signals of opposite polarity. Surrounding these well-known OH lines, we have discovered the presence of CN lines of the $\\Delta v=1$ band which show anomalous polarization profiles. Although the Stokes V signals of the OH lines are antisymmetric and with a sizable amplitude, the CN lines show almost negligible circular polarization. On the contrary, the linear polarization signals turn out to be much stronger in the CN lines than in the OH lines. Interestingly, these CN lines present striking antisymmetric linear polarization profiles, which we are able to explain and model via the Paschen-Back effect theory for diatomic molecules. The presence of such peculiar CN lines in the same spectral region of the OH lines may be useful to improve our empirical knowledg...

  6. Anomalous magnetostrictive effects in (Lal-xTbx)2/3Sr1/3MnO3

    Institute of Scientific and Technical Information of China (English)

    吴坚; 张世远

    2003-01-01

    A series of (La1-xTbx)2/3Srl/3MnO3 polycrystalline samples has been studied by means of x-ray diffraction,magnetostriction, and thermal expansion measurements. It has been found that this series undergoes a phase transition from a rhombohedral to an orthorhombic form at the doping level x≈0.20 at room temperature accompanied by an anisotropic magnetostriction up to -50×10-6 under a magnetic field of 1T. The linear and volume magnetostrictions vary with chemical composition, even change sign. At T=80K, the magnetostrictions for the samples of x=0.20 and 0.40 exhibit different behaviours. The sample of x=0.20 has positive volume and linear magnetostrictions and a negative anisotropic magnetostriction, while the sample of x=0.40 has an opposite behaviour. The magnitude of volume magnetostriction for both the samples is essential (-10-4) at T=80K under a magnetic field of 4T. We conclude that these anomalous effects are due to the charge delocalization and the structural phase transition between orthorhombic and rhombohedral forms induced by the applied magnetic field.

  7. Anomalous magnetostrictive effects in (La1-xTbx)2/3Sr1/3MnO3

    Institute of Scientific and Technical Information of China (English)

    吴坚; 张世远

    2003-01-01

    A series of (La1-xTbx)2/aSr1/3MnOa polycrystalline samples has been studied by means of x-ray diffraction,magnetostriction, and thermal expansion measurements. It has been found that this series undergoes a phase transitionfrom a rhombohedral to an orthorhombic form at the doping level x≈0.20 at room temperature accompanied by ananisotropic magnetostriction up to -50×10-6 under a magnetic field of iT. The linear and volume magnetostrictionsvary with chemical composition, even change sign. At T=80K, the magnetostrictions for the samples of x=0.20 and0.40 exhibit different behaviours. The sample of x=0.20 has positive volume and linear magnetostrictions and a neg-ative anisotropic magnetostriction, while the sample of x=0.40 has an opposite behaviour. The magnitude of volumemagnetostriction for both the samples is essential (~ 10-4) at T=80K under a magnetic field of 4T. We conclude thatthese anomalous effects are due to the charge delocalization and the structural phase transition between orthorhombicand rhombohedral forms induced by the applied magnetic field.

  8. Theory for the anomalous electron transport in Hall effect thrusters. I. Insights from particle-in-cell simulations

    Science.gov (United States)

    Lafleur, T.; Baalrud, S. D.; Chabert, P.

    2016-05-01

    Using a 1D particle-in-cell simulation with perpendicular electric, E0, and magnetic, B0, fields, and modelling the azimuthal direction (i.e., the E0 × B0 direction), we study the cross-field electron transport in Hall effect thrusters (HETs). For low plasma densities, the electron transport is found to be well described by classical electron-neutral collision theory, but at sufficiently high densities (representative of typical HETs), a strong instability is observed to significantly enhance the electron mobility, even in the absence of electron-neutral collisions. This instability is associated with correlated high-frequency (of the order of MHz) and short-wavelength (of the order of mm) fluctuations in both the electric field and the plasma density, which are shown to be the cause of the anomalous transport. Saturation of the instability is observed to occur due to a combination of ion-wave trapping in the E0 × B0 direction, and convection in the E0 direction.

  9. The effect of dietary and/or cosmetic argan oil on postmenopausal skin elasticity

    Directory of Open Access Journals (Sweden)

    Qiraouani Boucetta K

    2015-01-01

    Full Text Available Kenza Qiraouani Boucetta,1 Zoubida Charrouf,2 Hassan Aguenaou,3 Abdelfattah Derouiche,4 Yahya Bensouda1 1Research Team on Formulation and Biopharmacy, Research Center for Drug, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco; 2Faculty of Sciences, Mohammed V University, Rabat, Morocco; 3Mixed Unit of Research in Nutrition, ITU / CNESTEN, Ibn Tofail University, Kenitra, Morocco; 4Faculty of Sciences, Hassan II University, Casablanca, Morocco Background: During menopause, the decrease of estrogenic secretion induces the disruption of skin functioning, thus causing the decline in skin elasticity characteristic of skin aging. The purpose of this study was to evaluate in postmenopausal women the effect of daily consumption and/or application of argan oil on skin elasticity.Materials and methods: Sixty postmenopausal women consumed butter during the stabilization period and were randomly divided into two groups for the intervention period: the treatment group of 30 participants received dietary argan oil, the control group of 30 participants received olive oil, and both groups applied cosmetic argan oil in the left volar forearm during a 60-day period. Assessments of skin elasticity parameters, ie, the three R-parameters (R2 or gross-elasticity of the skin, R5 or net elasticity of the skin, and R7 or biological elasticity, and the resonance running time (RRT at both volar forearms of the two groups were performed during three visits: before starting oils consumption and application, after 30 days of oils consumption and application, and after 60 days of oils consumption and application.Results: The consumption of argan oil led to a significant increase of gross-elasticity of the skin (R2 (P<0.001, net elasticity of the skin (R5 (P<0.001, biological elasticity (R7 (P<0.001, and a significant decrease of RRT (P=0.002. The application of argan oil led to a significant increase of gross-elasticity of the skin (R2 (P<0.001, net

  10. Symmetry energy, neutron skin, and neutron star radius from chiral effective field theory interactions

    OpenAIRE

    Hebeler, K.; Schwenk, A.

    2014-01-01

    We discuss neutron matter calculations based on chiral effective field theory interactions and their predictions for the symmetry energy, the neutron skin of 208 Pb, and for the radius of neutron stars.

  11. Effects of a cellulose mask synthesized by a bacterium on facial skin characteristics and user satisfaction

    Directory of Open Access Journals (Sweden)

    Amnuaikit T

    2011-06-01

    Full Text Available Thanaporn Amnuaikit, Toon Chusuit, Panithi Raknam, Prapaporn BoonmeDepartment of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Songkhla, ThailandBackground: Cellulose masks obtained from natural sources such as bacteria are of interest as cosmetic devices for the treatment of dry skin because they not only improve hydration of the skin, but have low toxicity and are biodegradable. The aims of this study were to determine the in vivo effects of a cellulose mask obtained from Acetobacter xylinum on skin characteristics and to evaluate user satisfaction with the product.Methods: Thirty healthy Thai volunteers aged 21–40 years participated in the study. The volunteers were randomly separated into a control group and an experimental group. For the control group, volunteers were assigned to apply moist towels to the face for 25 minutes. For the experimental group, the volunteers were assigned to apply the masks, ie, translucent patches which could be fitted onto the face for the same period. The following week, the groups were changed over to the alternative treatment. Skin moisture, sebum, elasticity, texture, dullness, and desquamation levels were assessed using a system used for routine skin counseling before applying the trial product and five minutes after its removal. Degree of satisfaction with use of the cellulose mask was investigated using a five-point rating scale.Results: The cellulose mask increased moisture levels in the skin significantly more than moist towels (P < 0.05 after a single application. No obvious effects on other skin characteristics were found. The cellulose mask product rated around 4/5 on the satisfaction rating scale.Conclusions: A single application of the trial cellulose mask enhanced moisture uptake by facial skin. Users also reported being satisfied with the trial product.Keywords: bacterial cellulose, facial mask, skin characteristics, skin hydration, user

  12. Intrinsic quantum spin Hall and anomalous Hall effects in h-Sb/Bi epitaxial growth on a ferromagnetic MnO2 thin film

    Science.gov (United States)

    Zhou, Jian; Sun, Qiang; Wang, Qian; Kawazoe, Yoshiyuki; Jena, Puru

    2016-05-01

    Exploring a two-dimensional intrinsic quantum spin Hall state with a large band gap as well as an anomalous Hall state in realizable materials is one of the most fundamental and important goals for future applications in spintronics, valleytronics, and quantum computing. Here, by combining first-principles calculations with a tight-binding model, we predict that Sb or Bi can epitaxially grow on a stable and ferromagnetic MnO2 thin film substrate, forming a flat honeycomb sheet. The flatness of Sb or Bi provides an opportunity for the existence of Dirac points in the Brillouin zone, with its position effectively tuned by surface hydrogenation. The Dirac points in spin up and spin down channels split due to the proximity effects induced by MnO2. In the presence of both intrinsic and Rashba spin-orbit coupling, we find two band gaps exhibiting a large band gap quantum spin Hall state and a nearly quantized anomalous Hall state which can be tuned by adjusting the Fermi level. Our findings provide an efficient way to realize both quantized intrinsic spin Hall conductivity and anomalous Hall conductivity in a single material.Exploring a two-dimensional intrinsic quantum spin Hall state with a large band gap as well as an anomalous Hall state in realizable materials is one of the most fundamental and important goals for future applications in spintronics, valleytronics, and quantum computing. Here, by combining first-principles calculations with a tight-binding model, we predict that Sb or Bi can epitaxially grow on a stable and ferromagnetic MnO2 thin film substrate, forming a flat honeycomb sheet. The flatness of Sb or Bi provides an opportunity for the existence of Dirac points in the Brillouin zone, with its position effectively tuned by surface hydrogenation. The Dirac points in spin up and spin down channels split due to the proximity effects induced by MnO2. In the presence of both intrinsic and Rashba spin-orbit coupling, we find two band gaps exhibiting a large

  13. DeoxyArbutin: a novel reversible tyrosinase inhibitor with effective in vivo skin lightening potency.

    Science.gov (United States)

    Boissy, Raymond E; Visscher, Marty; DeLong, Mitchell A

    2005-08-01

    Modulation of melanogenesis in the melanocytes can be achieved using chemicals that share structural homologies with the substrate tyrosine and as thus competitively inhibit the catalytic function of tyrosinase. We have developed a new tyrosinase inhibitor, deoxyArbutin (dA), based on this premise. DeoxyArbutin demonstrates effective inhibition of mushroom tyrosinase in vitro with a Ki that is 10-fold lower that hydroquinone (HQ) and 350-fold lower than arbutin. In a hairless, pigmented guinea pig model, dA demonstrated rapid and sustained skin lightening that was completely reversible within 8 weeks after halt in topical application. In contrast, HQ induced a short but unsustained skin lightening effect whereas kojic acid and arbutin exhibit no skin lightening effect. Results from a panel of safety tests supported the overall establishment of dA as an actionable molecule. In a human clinical trial, topical treatment of dA for 12 weeks resulted in a significant or slight reduction in overall skin lightness and improvement of solar lentigines in a population of light skin or dark skin individuals, respectively. These data demonstrate that dA has potential tyrosinase inhibitory activity that can result in skin lightening and may be used to ameliorate hyperpigmentary lesions.

  14. The effect of Kinesiotaping to the skin temperature – Pilot study

    OpenAIRE

    Holma, Teemu

    2014-01-01

    Aim of this study was to research whether kinesiotape has effect to skin temperature. Subjects of this study were 32 asymptomatic students of Satakunta University of Applied Sciences, 20 females and 15 males. The exclusion criteria were: recent back pain or musculoskeletal diseases on back area skin irritations and diseases on taping site. To assess the effect of kinesiotape all the subjects were taped with 30 cm taped from Superios Posterios Iliac Spine(SPIS) upwards to the ribcage. Befo...

  15. Effects of femtosecond laser radiation on the skin

    Science.gov (United States)

    Rogov, P. Yu; Bespalov, V. G.

    2016-08-01

    A mathematical model of linear and nonlinear processes is presented occurring under the influence of femtosecond laser radiation on the skin. There was held an analysis and the numerical solution of an equation system describing the dynamics of the electron and phonon subsystems were received. The results can be used to determine the maximum permissible levels of energy generated by femtosecond laser systems and the establishment of Russian laser safety standards for femtosecond laser systems.

  16. The biodisposition and hypertrichotic effects of bimatoprost in mouse skin.

    Science.gov (United States)

    Woodward, David F; Tang, Elaine S-H; Attar, Mayssa; Wang, Jenny W

    2013-02-01

    Studies on bimatoprost were performed with two objectives: (i) to determine whether bimatoprost possesses hair growth-stimulating properties beyond eyelash hypertrichosis and (ii) to investigate the biodisposition of bimatoprost in skin for the first time. Bimatoprost, at the dose used clinically for eyelash growth (0.03%) and given once daily for 14 days, increased pelage hair growth in C57/black 6 mice. This occurred as a much earlier onset of new hair growth in shaved mice and the time taken to achieve complete hair regrowth, according to photographic documentation and visual assessment. Bimatoprost biodisposition in the skin was determined at three concentrations: 0.01%, 0.03% and 0.06%. Dose-dependent C(max) values were obtained (3.41, 6.74, 12.3 μg/g tissue), and cutaneous bimatoprost was well maintained for 24 h following a single dose. Bimatoprost was recovered from the skin only as the intact molecule, with no detectable levels of metabolites. Thus, bimatoprost produces hypertrichosis as the intact molecule.

  17. The effect of saline iontophoresis on skin integrity in human volunteers. I. Methodology and reproducibility.

    Science.gov (United States)

    Camel, E; O'Connell, M; Sage, B; Gross, M; Maibach, H

    1996-08-01

    This study, conducted in 36 human volunteers, was an evaluation of the effects of saline iontophoresis on skin temperature, irritation, and barrier function. The major objectives were to assess the effects of low-level ionic currents, to validate the proposed methodology of assessment, and to establish reproducibility in repeated saline iontophoresis applications. This was the first of a multistage study designed to assess the safety of 24-hr saline iontophoresis episodes at selected currents and current densities. Since an iontophoresis patch challenges the skin barrier both by occluding the skin surface and by passing ionic current through the skin, the experimental protocol was designed to permit measurement of the contribution of each of these processes to the overall response. In this first stage we investigated the effect of 10 min of current delivery, at 0.1 mA/cm2 on a 1-cm2 area patch and 0.2 mA/cm2 on a 6.5-cm2 area patch compared to unpowered control patches. Twelve subjects were tested under each condition on two separate occasions to examine reproducibility of the response variable measurements. A further 12 subjects were tested once under the 0.2 mA/cm2, 6.5-cm2 condition. Skin irritation was evaluated via repeated measurements of transepidermal water loss, capacitance, skin temperature, skin color, and a visual scoring system, before the iontophoresis episode and after patch removal. No damage to skin barrier function in terms of skin-water loss or skin-water content was detected. Slight, subclinical, short-lasting erythema was observed for both conditions. Assessment of correlation coefficients showed highly statistically significant indications of reproducibility for all five response variables measured. The experimental design, in combination with a repeated measures analysis, provided clear separation of the occlusion and ionic current components of the iontophoretic patch challenge. Further, the repeated measures analysis gave a highly sensitive

  18. Effect of activation volume on the pressure-induced anomalous resistances in EuFe{sub 2}As{sub 2}

    Energy Technology Data Exchange (ETDEWEB)

    Kwang-Hua, Chu W., E-mail: xajialj@gmail.com [School of Mechanical Engineering, Qinghai University, Xining 810016 (China); Transfer Centre, 3/F, No. 24, Lane 260, Section 1, Mucha Road, Taipei 116, Taiwan, ROC (China)

    2013-03-29

    Highlights: ► Use quantum chemistry to capture the anomalous transition of EuFe{sub 2}As{sub 2}. ► Activation energy and volume are crucial to the critical temperature. ► Pressure effect of EuFe{sub 2}As{sub 2}-resistances can be captured via our approach. - Abstract: We illustrate the effect of activation volume on the pressure-induced anomalous transitional resistances in EuFe{sub 2}As{sub 2} as well as the frictionless transport of many condensed electrons in FeAs based materials by using the verified transition-state approach which is borrowed from the quantum chemistry. Our results suggest that tuning of activation volume could enhance the onset temperature of critical transitional states.

  19. Protective effects of oleum curcumae wenchowensis on skin damage due to UVB

    International Nuclear Information System (INIS)

    Objective: To study the protective effects of oleum curcumae wenchowensis on skin damage exposed to UVB and its mechanism, and to provide the experimental basis for the protection of skin damage exposed to UVB. Methods: The skin of guinea pigs was exposed to UVB (28.38 J/cm2 · 30 d) to establish the oxidative damage model. The skin erythema and the rough were observed during the experiment; the thickness of epiderm and the number of fibroblast were observed under light microscope after the experiment. The activities of GSH-Px, SOD, CAT and T-AOC and the contain of MDA in the supernate of skin homogenate were detected with biochemical methods. Results: The epiderm in UVB exposure group and blank group thickened, but that in protective group weren't observed; the number of fibroblast in UVB exposure group and blank group decreased, while that in protective group increased, but that in control group didn't. The content of MDA in the supemate of skin homogenate in UVB exposure group and blank group increased, but that in protective group deceased, and the activities of GSH-Px, SOD, CAT and T-AOC in UVB exposure group and blank group decreased, but those in protective group increased, and control group had no change. Conclusions: Oleum curcumae wenchowensis has the protective effects on skin damage exposed to UVB, which may be mediated by increasing the contain of antioxidases and eliminating the flee radical. (authors)

  20. The Effect of Adipose-Derived Stem Cells on Full-Thickness Skin Grafts.

    Science.gov (United States)

    Wang, Juan; Hao, Haojie; Huang, Hong; Chen, Deyun; Han, Yan; Han, Weidong

    2016-01-01

    Background. The purpose of this study was to evaluate the effects of ASCs on full-thickness skin grafts. Specifically, we investigated the anti-inflammatory effects of ASCs that are mediated via regulation of the phenotypes of activated macrophages. Methods. ASCs were isolated, cultured, and injected under full-thickness skin grafts in 15 rats (ASC group). An additional 15 rats served as controls (PBS group). Skin graft survival assessment and vascularization detection were assessed with H&E staining and laser Doppler blood flowmetry (LDF). The effects of ASCs on angiogenesis, anti-inflammation, collagen accumulation-promoting, and antiscarring were assessed. Results. We found that the skin graft survival rate was significantly increased in the ASC group. The neovascularization, collagen deposition, collagen type I to type III ratio, and levels of VEGF and TGF-β3 in the ASC group were markedly higher than those in the PBS group at day 14. Additionally, in the ASC group, the levels of iNOS, IL-1β, and TNF-α were remarkably decreased, whereas the levels of IL-10 and Arg-1 were substantially increased. Conclusions. Our results confirm that ASCs transplantation can effectively improve full-thickness skin graft survival. Additionally, the anti-inflammatory role of ASCs may indirectly contribute to skin graft survival via its effect on macrophage polarization. PMID:27413735

  1. Anomalous Hall effect in anatase Co:TiO2 ferromagnetic semiconductor

    NARCIS (Netherlands)

    Ramaneti, R.; Lodder, J.C.; Jansen, R.

    2007-01-01

    We have investigated the effects of modification of the SrTiO3 /Co interface as well as the SrTiO3 barrier on the tunnel magnetoresistance TMR of La0.67Sr0.33MnO3 /SrTiO3 /Co junctions. Modification was realized by the introduction of one atomic layer of either TiO2 or SrO at the SrTiO3 /Co interfac

  2. Efimov effect and anomalous transport properties of a quantum Lorentz gas

    International Nuclear Information System (INIS)

    The Lorentz gas is one of the simplest many-body systems which admits a detailed theoretical analysis still having a meaningful physical interpretation. The author studies a complication for the description of the equilibrium state of a gas due to the so called Efimov effect, being an anomaly of the quantum mechanical three-body system. In statistical mechanical studies concerning the thermodynamic properties of gases it is usually assumed that the constituents interact via short-range potentials, which excludes for instance the Coulomb gas. The author investigates the consequences of the effective long-range behaviour due to the Efimov effect in the three-body sub-systems for a binary gas mixture. In particular problems arise in the cluster expansion of the quantum mechanical partition function where it can readily be shown that the bound-state part of the three-particle contribution diverges logarithmically at the Efimov point. The question is whether this implies the divergence of the complete three particle contribution or not. Some aspects of the non-equilibrium behaviour of the quantum Lorentz gas are studied. (Auth.)

  3. Flavanone silibinin treatment attenuates nitrogen mustard-induced toxic effects in mouse skin

    Energy Technology Data Exchange (ETDEWEB)

    Jain, Anil K.; Tewari-Singh, Neera; Inturi, Swetha; Kumar, Dileep [Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO 80045 (United States); Orlicky, David J. [Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045 (United States); Agarwal, Chapla [Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO 80045 (United States); White, Carl W. [Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045USA (United States); Agarwal, Rajesh, E-mail: Rajesh.Agarwal@UCDenver.edu [Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO 80045 (United States)

    2015-05-15

    Currently, there is no effective antidote to prevent skin injuries by sulfur mustard (SM) and nitrogen mustard (NM), which are vesicating agents with potential relevance to chemical warfare, terrorist attacks, or industrial/laboratory accidents. Our earlier report has demonstrated the therapeutic efficacy of silibinin, a natural flavanone, in reversing monofunctional alkylating SM analog 2-chloroethyl ethyl sulfide-induced toxic effects in mouse skin. To translate this effect to a bifunctional alkylating vesicant, herein, efficacy studies were carried out with NM. Topical application of silibinin (1 or 2 mg) 30 min after NM exposure on the dorsal skin of male SKH-1 hairless mice significantly decreased NM-induced toxic lesions at 24, 72 or 120 h post-exposure. Specifically, silibinin treatment resulted in dose-dependent reduction of NM-induced increase in epidermal thickness, dead and denuded epidermis, parakeratosis and microvesication. Higher silibinin dose also caused a 79% and 51%reversal in NM-induced increases in myeloperoxidase activity and COX-2 levels, respectively. Furthermore, silibinin completely prevented NM-induced H2A.X phosphorylation, indicating reversal of DNA damage which could be an oxidative DNA damage as evidenced by high levels of 8-oxodG in NM-exposed mouse skin that was significantly reversed by silibinin. Together, these findings suggest that attenuation of NM-induced skin injury by silibinin is due to its effects on the pathways associated with DNA damage, inflammation, vesication and oxidative stress. In conclusion, results presented here support the optimization of silibinin as an effective treatment of skin injury by vesicants. - Highlights: • Silibinin treatment attenuated nitrogen mustard (NM)-induced skin injury. • Silibinin affects pathways associated with DNA damage, inflammation and vesication. • The efficacy of silibinin could also be associated with oxidative stress. • These results support testing and optimization of

  4. Chiral magnetic effect and anomalous transport from real-time lattice simulations

    CERN Document Server

    Mueller, Niklas; Sharma, Sayantan

    2016-01-01

    We present a first-principle study of anomaly induced transport phenomena by performing real-time lattice simulations with dynamical fermions coupled simultaneously to non-Abelian $SU(N_c)$ and Abelian $U(1)$ gauge fields. Investigating the behavior of vector and axial currents during a sphaleron transition in the presence of an external magnetic field, we demonstrate how the interplay of the Chiral magnetic (CME) and Chiral separation effect (CSE) lead to the formation of a propagating wave. We further analyze the dependence of the magnitude of the induced vector current and the propagation of the wave on the amount of explicit chiral symmetry breaking due to finite quark mass.

  5. Anomalous quantum and isotope effects in water clusters: Physical phenomenon, model artifact, or bad approximation?

    CERN Document Server

    Brown, Sandra E

    2014-01-01

    Free energy differences $\\Delta F:=F-F_{\\text{prism}}$ are computed for several isomers of water hexamer relative to the "prism" isomer using the self-consistent phonons method. %$\\Delta F:=F-F({prism})$ We consider the isotope effect defined by the quantity $\\delta F_{D_2O}:=\\Delta F_{\\rm D_2O}-\\Delta F_{\\rm H_2O}$, and the quantum effect, $\\delta F_{\\hbar=0}:=\\Delta F_{\\hbar=0}-\\Delta F_{\\rm H_2O}$, and evaluate them using different flexible water models. While both $\\delta F_{D_2O}$ and $\\delta F_{\\hbar=0}$ are found to be rather small for all of the potentials, they are especially small for two of the empirical models, q-TIP4P/F and TTM3-F, compared to q-SPC/Fw and the two {\\it abinitio}-based models, WHBB and HBB2-pol. This qualitative difference in the properties of different water models cannot be explained by one being "more accurate" than the other. We speculate as to whether the observed anomalies are caused by the special properties of water systems, or are an artifact of either the potential energ...

  6. Anomalous Hall effect in epitaxial ferrimagnetic anti-perovskite Mn{sub 4−x}Dy{sub x}N films

    Energy Technology Data Exchange (ETDEWEB)

    Meng, M.; Wu, S. X., E-mail: wushx3@mail.sysu.edu.cn; Zhou, W. Q.; Ren, L. Z.; Wang, Y. J.; Wang, G. L.; Li, S. W., E-mail: stslsw@mail.sysu.edu.cn [State Key Laboratory of Optoelectronic Materials and Technologies, School of Physics and Engineering, Sun Yat-Sen University, Guangzhou 510275 (China)

    2015-08-07

    Anomalous Hall effect (AHE) has been studied for ferrimagnetic antiperovskite Mn{sub 4−x}Dy{sub x}N films grown by molecular-beam epitaxy. The introduction of Dy changes the AHE dramatically, even changes its sign, while the variations in magnetization are negligible. Two sign reversals of the AHE (negative-positive-negative) are ascribed to the variation of charge carriers as a result of Fermi surface reconstruction. We further demonstrate that the AHE current J{sub AH} is dissipationless (independent of the scattering rate), by confirming that anomalous Hall conductivity, σ{sub AH}, is proportional to the carrier density n at 5 K. Our study may provide a route to further utilize antiperovskite manganese nitrides in spintronics.

  7. Effect of skin hydration on the dynamics of fingertip gripping contact

    Science.gov (United States)

    André, T.; Lévesque, V.; Hayward, V.; Lefèvre, P.; Thonnard, J.-L.

    2011-01-01

    The dynamics of fingertip contact manifest themselves in the complex skin movements observed during the transition from a stuck state to a fully developed slip. While investigating this transition, we found that it depended on skin hydration. To quantify this dependency, we asked subjects to slide their index fingertip on a glass surface while keeping the normal component of the interaction force constant with the help of visual feedback. Skin deformation inside the contact region was imaged with an optical apparatus that allowed us to quantify the relative sizes of the slipping and sticking regions. The ratio of the stuck skin area to the total contact area decreased linearly from 1 to 0 when the tangential force component increased from 0 to a maximum. The slope of this relationship was inversely correlated to the normal force component. The skin hydration level dramatically affected the dynamics of the contact encapsulated in the course of evolution from sticking to slipping. The specific effect was to reduce the tendency of a contact to slip, regardless of the variations of the coefficient of friction. Since grips were more unstable under dry skin conditions, our results suggest that the nervous system responds to dry skin by exaggerated grip forces that cannot be simply explained by a change in the coefficient of friction. PMID:21490002

  8. Spectrum of anomalous magnetohydrodynamics

    Science.gov (United States)

    Giovannini, Massimo

    2016-05-01

    The equations of anomalous magnetohydrodynamics describe an Abelian plasma where conduction and chiral currents are simultaneously present and constrained by the second law of thermodynamics. At high frequencies the magnetic currents play the leading role, and the spectrum is dominated by two-fluid effects. The system behaves instead as a single fluid in the low-frequency regime where the vortical currents induce potentially large hypermagnetic fields. After deriving the physical solutions of the generalized Appleton-Hartree equation, the corresponding dispersion relations are scrutinized and compared with the results valid for cold plasmas. Hypermagnetic knots and fluid vortices can be concurrently present at very low frequencies and suggest a qualitatively different dynamics of the hydromagnetic nonlinearities.

  9. Optically Anomalous Crystals

    CERN Document Server

    Shtukenberg, Alexander; Kahr, Bart

    2007-01-01

    Optical anomalies in crystals are puzzles that collectively constituted the greatest unsolved problems in crystallography in the 19th Century. The most common anomaly is a discrepancy between a crystal’s symmetry as determined by its shape or by X-ray analysis, and that determined by monitoring the polarization state of traversing light. These discrepancies were perceived as a great impediment to the development of the sciences of crystals on the basis of Curie’s Symmetry Principle, the grand organizing idea in the physical sciences to emerge in the latter half of the 19th Century. Optically Anomalous Crystals begins with an historical introduction covering the contributions of Brewster, Biot, Mallard, Brauns, Tamman, and many other distinguished crystallographers. From this follows a tutorial in crystal optics. Further chapters discuss the two main mechanisms of optical dissymmetry: 1. the piezo-optic effect, and 2. the kinetic ordering of atoms. The text then tackles complex, inhomogeneous crystals, and...

  10. Strong Quantum Size Effects in Pb(111) Thin Films Mediated by Anomalous Friedel Oscillations

    Science.gov (United States)

    Jia, Yu; Wu, Biao; Li, Chong; Einstein, T. L.; Weitering, H. H.; Zhang, Zhenyu

    2010-08-01

    Using first-principles calculations within density functional theory, we study Friedel oscillations (FOs) in the electron density at different metal surfaces and their influence on the lattice relaxation and stability of ultrathin metal films. We show that the FOs at the Pb(111) surface decay as 1/x with the distance x from the surface, different from the conventional 1/x2 power law at other metal surfaces. The underlying physical reason for this striking difference is tied to the strong nesting of the two different Fermi sheets along the Pb(111) direction. The interference of the strong FOs emanating from the two surfaces of a Pb(111) film, in turn, not only results in superoscillatory interlayer relaxations around the center of the film, but also determines its stability in the quantum regime. As a simple and generic picture, the present findings also explain why quantum size effects are exceptionally robust in Pb(111) films.

  11. Possible anomalous doppler shift effect in superconductor Sr sub 2 RuO sub 4

    CERN Document Server

    Tanaka, Y; Tanuma, Y; Kashiwaya, S

    2003-01-01

    The effect of Doppler shift is studied in a model for the alpha-beta bands of Sr sub 2 RuO sub 4 consisting of two hybridized one-dimensional (1D) bands. Assuming a superconducting gap with nodes in a diagonal direction, we examine the oscillation of surface density of states and thermal conductivity under a rotating magnetic field. Upon varying the strength of hybridization, the oscillation of these quantities is found to exhibit 2D to 1D crossover. In the crossover regime, which corresponds to the actual Sr sub 2 RuO sub 4 , the thermal conductivity exhibits a two-fold-symmetry oscillation, while a four-fold-symmetry component in the oscillation is barely detectable.

  12. Cytotoxic Effects of the Ethanol Bane Skin Extract in Human Prostate Cancer Pc3 Cells

    Science.gov (United States)

    Amiri, Maryam; Kazerouni, Faranak; Namaki, Saeed; Darbandi Tamijani, Hassan; Rahimipour, Hooman; Boroumand, Nasrin; Barghi, Siyamak; Ebrahimi, Nazanin; Gheibi Hayat, Seyed Mohammad

    2016-01-01

    Background: It is extensively supposed that vegetarian diet could affect cancer progress and increase the influence of formal chemotherapy. Objectives: The present study was designed to determine the effect of the ethanol Bane skin extract against chemo resistant prostate cancer PC3 cells. Materials and Methods: PC3 and L929 cells were cultivated and then incubated in the ethanol Bane skin extract with various concentrations of 0.78, 1.5, 3.13, 6.25, 12.5 mg/mL in 3 times 24, 48, 72 hours. Cytotoxic effect of the ethanol Bane skin extract on PC3 and L929 cells was examined by MTT assay after 24, 48, and 72 hours. Morphology of PC3 cells was evaluated by Gimsa staining. Results: The ethanol Bane skin extract inhibited proliferation and caused cell death with IC50 values of 2.8 mg/mL on PC3 cells and the IC50 was 6.1 mg/mL on l929 cells. Morphological changes and apoptotic bodies were observed in PC3 cells faced with the ethanol Bane skin extract by staining with Gimsa. Conclusions: The ethanol Bane skin extract could repress the growth of PC3 cell line. This inhibitory effect of the Bane extract depended on the dose and the time on PC3. The result of this study shows that the ethanol Bane skin extract includes photochemical and inhibitory function against proliferation and inducer of apoptosis in human prostate cancer PC3 cells and also has less cytotoxic effect on l929 than PC3 cells. The ethanol Bane skin extract might be a good candidate for the new herbal anticancer drug. PMID:27482333

  13. Effect of Red Clover Isoflavones over Skin, Appendages, and Mucosal Status in Postmenopausal Women

    OpenAIRE

    Markus Lipovac; Peter Chedraui; Christine Gruenhut; Anca Gocan; Christine Kurz; Benedikt Neuber; Martin Imhof

    2011-01-01

    Objective. Evaluate in postmenopausal women the effect of red clover extract (RCE) isoflavones over subjective status of skin, appendages, and several mucosal sites. Method. Postmenopausal women (n = 109) were randomly assigned to receive either two daily capsules of the active compound (80 mg RCE, Group A) or placebo of equal appearance (Group B) for a 90-day period. After a washout period of 7 days, medication was crossed over and taken for 90 days more. Subjective improvement of skin, appe...

  14. Effects of nebivolol on skin flap survival: A randomized experimental study in rats

    OpenAIRE

    Gideroglu, Kaan; Alagoz, Sahin; Uygur, Fatih; Evinc, Rahmi; Celikoz, Bahattin; Bugdayci, Guler

    2008-01-01

    Background: Skin flaps are among the basic treatment options in the reconstruction of soft tissue defects. To improve skin flap survival, a variety of methods, including pharmacologic agents, have been investigated. The effectiveness of anticoagulants, antioxidants, anti-inflammatory drugs, and vasodilatory drugs in improving flap survival has been studied. Nebivolol is a new-generation selective β1-adrenoreceptor blocking agent that has vasodilatory, antithrombotic, antioxidative, and anti- ...

  15. Skin penetration and antioxidant effect of cosmeto-textiles with gallic acid

    OpenAIRE

    Alonso, Cristina; Marti, Meritxell; Barba, Clara; Lis Arias, Manuel José; Rubio, Laia; Coderch, Luisa

    2015-01-01

    In this work, the antioxidant gallic acid (GA) has been encapsulated in microspheres prepared with poly-e-caprolactone (PCL) and incorporated into polyamide (PA) obtaining the cosmeto-textile. The topical application of the cosmeto-textile provides a reservoir effect in the skin delivery of GA. The close contact of the cosmeto-textile, containing microsphere-encapsulated GA (ME-GA), with the skin and their corresponding occlusion, may be the main reasons that explain the crossing of active pr...

  16. The epilatory effects of trypsin on human skin, applied via lecithin reverse micelles

    OpenAIRE

    Protopapa, E. E.; Xenakis, Aristotelis; Avramiotis, S.; Prodromou, E.V.; Koukaki, S.M.

    2008-01-01

    A method of epilation using reverse micelles containing the proteolytic enzyme, trypsin, is described based on previous experimental findings on degenerative effects of proteolytic enzymes on hair follicles and follicle stem cells of guinea pigs and mice. The method involves rubbing of the preparation on wax epilated skin and leads to removal of hair from various skin regions, such as face, shoulders, arms and legs. The many advantages of this method renders it the method of choice for hai...

  17. Neutron Skin Thickness of Nuclei and Effective Nucleon-Nucleon Interactions

    Institute of Scientific and Technical Information of China (English)

    LIU Min; WANG Ning; LI Zhu-Xia; WU Xi-Zhen

    2006-01-01

    @@ The Skyrme energy density functional is applied to study the ground state properties of a series of finite nuclei.The charge rms radii, neutron rms radii, and the neutron skin thickness for some nuclei are calculated and compared with the experimental data. The constraint on the effective interactions, especially, the density dependence of the isospin-dependent part of Skyrme interactions is extracted by the data of neutron skin thicknesses of 208 pb and isotopes of Sn.

  18. Intrinsic quantum spin Hall and anomalous Hall effects in h-Sb/Bi epitaxial growth on a ferromagnetic MnO2 thin film.

    Science.gov (United States)

    Zhou, Jian; Sun, Qiang; Wang, Qian; Kawazoe, Yoshiyuki; Jena, Puru

    2016-06-01

    Exploring a two-dimensional intrinsic quantum spin Hall state with a large band gap as well as an anomalous Hall state in realizable materials is one of the most fundamental and important goals for future applications in spintronics, valleytronics, and quantum computing. Here, by combining first-principles calculations with a tight-binding model, we predict that Sb or Bi can epitaxially grow on a stable and ferromagnetic MnO2 thin film substrate, forming a flat honeycomb sheet. The flatness of Sb or Bi provides an opportunity for the existence of Dirac points in the Brillouin zone, with its position effectively tuned by surface hydrogenation. The Dirac points in spin up and spin down channels split due to the proximity effects induced by MnO2. In the presence of both intrinsic and Rashba spin-orbit coupling, we find two band gaps exhibiting a large band gap quantum spin Hall state and a nearly quantized anomalous Hall state which can be tuned by adjusting the Fermi level. Our findings provide an efficient way to realize both quantized intrinsic spin Hall conductivity and anomalous Hall conductivity in a single material. PMID:27181160

  19. Hot electron production, anomalous absorption, and effect of intense electromagnetic fields on inverse bremsstrahlung absorption near the electron plasma frequency

    International Nuclear Information System (INIS)

    Anomalous heating was studied on a well-controlled low-density plasma subjected to short microwave pulses. Absorption measurements along with parametric instabilities are described. The influence of intense ac electric fields on the electron-ion collision rate in the plasma is also discussed

  20. A comparison of the effects of captopril and enalapril on skin responses to intradermal bradykinin and skin blood flow in the human forearm.

    OpenAIRE

    LI KAM WA, T. C.; Cooke, E D; Turner, P

    1993-01-01

    1. The effects of captopril and enalapril on skin responses to intradermal injections of bradykinin and skin blood flow in the forearm were investigated in this randomised, double-blind, placebo-controlled, cross-over study. 2. Intradermal injections of 0, 1, 2.5 and 5 micrograms of bradykinin in 0.9% sodium chloride were made into the forearm of twelve healthy volunteers before and at 2, 6 and 24 h after single oral doses of 25 mg captopril, 10 mg enalapril or placebo. Forearm skin blood flo...

  1. Anomalous extracellular diffusion in rat cerebellum.

    Science.gov (United States)

    Xiao, Fanrong; Hrabe, Jan; Hrabetova, Sabina

    2015-05-01

    Extracellular space (ECS) is a major channel transporting biologically active molecules and drugs in the brain. Diffusion-mediated transport of these substances is hindered by the ECS structure but the microscopic basis of this hindrance is not fully understood. One hypothesis proposes that the hindrance originates in large part from the presence of dead-space (DS) microdomains that can transiently retain diffusing molecules. Because previous theoretical and modeling work reported an initial period of anomalous diffusion in similar environments, we expected that brain regions densely populated by DS microdomains would exhibit anomalous extracellular diffusion. Specifically, we targeted granular layers (GL) of rat and turtle cerebella that are populated with large and geometrically complex glomeruli. The integrative optical imaging (IOI) method was employed to evaluate diffusion of fluorophore-labeled dextran (MW 3000) in GL, and the IOI data analysis was adapted to quantify the anomalous diffusion exponent dw from the IOI records. Diffusion was significantly anomalous in rat GL, where dw reached 4.8. In the geometrically simpler turtle GL, dw was elevated but not robustly anomalous (dw = 2.6). The experimental work was complemented by numerical Monte Carlo simulations of anomalous ECS diffusion in several three-dimensional tissue models containing glomeruli-like structures. It demonstrated that both the duration of transiently anomalous diffusion and the anomalous exponent depend on the size of model glomeruli and the degree of their wrapping. In conclusion, we have found anomalous extracellular diffusion in the GL of rat cerebellum. This finding lends support to the DS microdomain hypothesis. Transiently anomalous diffusion also has a profound effect on the spatiotemporal distribution of molecules released into the ECS, especially at diffusion distances on the order of a few cell diameters, speeding up short-range diffusion-mediated signals in less permeable

  2. Comparison of skin effects of immediate treatment modalities in experimentally induced hydrofluoric acid skin burns.

    Science.gov (United States)

    Songur, Meltem K; Akdemir, Ovunc; Lineaweaver, William C; Cavusoglu, Turker; Ozsarac, Murat; Aktug, Huseyin; Songur, Ecmel; Tiftikcioglu, Yigit O

    2015-12-01

    Hydrofluoric acid (HF) burns cause immediate damage and painful long-term sequellae. Traditionally, chelating agents have been used as the initial treatment for such burns. We have introduced epidermal growth factor (EGF) into an HF model to compare EGF with Ca(2+) and Mg(2+) treatments; 40 Sprague Dawley rats were divided into five groups. Each rat suffered a 6 × 4 cm(2) burn induced by 40% HF. Group 1 had no treatment, group 2 had saline injected beneath the burn, group 3 received magnesium sulphate injections, group 4 received calcium gluconate and group 5 received EGF. Specimens were evaluated via planimetry and biopsy at intervals of 4, 8, 24 and 72 hours. Fluid losses were significantly less in the Mg(2+) and EGF groups. The EGF group had the smallest burn area, least oedema, least polymorphonuclear granulocyte (PMN) infiltration, most angiogenesis and highest fibroblast proliferation of any group (P < 0·005). EGF limited HF damage morphologically and histologically more effectively than Ca(2+) or Mg(2+). This finding indicates that HF treatment via growth factors may be an improvement over chelation therapy.

  3. Antioxidant effects of an ozonized theobroma oil formulation on damaged-inflammatory rat skin

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez, Y.; Diaz, M.F.; Hernandez, F.; Gila, D.; Ga, G.

    2011-07-01

    The aim of this study was to determine whether a cosmetic formulation elaborated with ozonized theobroma oil may exert beneficial effects in the restoring of the antioxidant activity on the skin of rats previously irradiated with ultraviolet light. 0.5 g of the formulation was applied on the skin of rats for five days. Superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT) activity were determined in a homogenate of rat skin. Malondialdehyde (MDA), conjugated dienes (CD) and total hydroperoxide (THP) content were determined as biomarkers of oxidative stress. Using these parameters, antioxidant and oxidant activity, redox index and oxidative stress grade were determined. The total antioxidant activity was significantly increased while the redox index, total oxidant activity and oxidative stress grade decreased significantly in damaged rats treated with the formulation. These results show the antioxidant properties of the cosmetic formulation due to the stimulation of antioxidant enzymes such as SOD and GPx, preventing skin injury induced by ultraviolet irradiation. (Author).

  4. Antioxidant effects of an ozonized theobroma oil formulation on damaged-inflammatory rat skin

    International Nuclear Information System (INIS)

    The aim of this study was to determine whether a cosmetic formulation elaborated with ozonized theobroma oil may exert beneficial effects in the restoring of the antioxidant activity on the skin of rats previously irradiated with ultraviolet light. 0.5 g of the formulation was applied on the skin of rats for five days. Superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT) activity were determined in a homogenate of rat skin. Malondialdehyde (MDA), conjugated dienes (CD) and total hydroperoxide (THP) content were determined as biomarkers of oxidative stress. Using these parameters, antioxidant and oxidant activity, redox index and oxidative stress grade were determined. The total antioxidant activity was significantly increased while the redox index, total oxidant activity and oxidative stress grade decreased significantly in damaged rats treated with the formulation. These results show the antioxidant properties of the cosmetic formulation due to the stimulation of antioxidant enzymes such as SOD and GPx, preventing skin injury induced by ultraviolet irradiation. (Author).

  5. Synchronization of skin ablation and microjet injection for an effective transdermal drug delivery

    Science.gov (United States)

    Jang, Hun-jae; Yeo, Seonggu; Yoh, Jack J.

    2016-04-01

    An Er:YAG laser with 2940-nm wavelength and 150-µs pulse duration was built for the purpose of combined ablation and microjet injection. A shorter pulse duration compared to common erbium lasers in dentistry is desirable for a synchronization of skin ablation and subsequent microjet injection into target skin for transdermal injection of liquid dose. A single laser beam is split into two for an optimal energy of pre-ablation of skin and the residual energy allocated to a microjet ejection. A newly designed injector consists of an L-shaped chamber and a parabolic mirror in a single unit, and the handheld laser is a part of an integrated system requiring no optical fiber. Through various injection tests using the porcine skin, the effectiveness of the new delivery system is herein evaluated.

  6. French Maritime Pine Bark Extract (Pycnogenol®) Effects on Human Skin: Clinical and Molecular Evidence.

    Science.gov (United States)

    Grether-Beck, Susanne; Marini, Alessandra; Jaenicke, Thomas; Krutmann, Jean

    2016-01-01

    Nutritional strategies to benefit skin health are of growing importance. Current approaches mainly involve nutritional supplements containing antioxidants which were initially designed to protect human skin against ultraviolet radiation-induced damage. Within recent years, however, a growing number of studies suggests that the beneficial effects of these products clearly extend beyond photoprotection. In this review we take the nutritional supplement Pycnogenol®, which is based on an extract prepared from French marine pine bark extract, as an example to illustrate this development. Accordingly, the existing data provide compelling evidence that Pycnogenol® intake does not only provide photoprotection, but may be used to (i) reduce hyperpigmentation of human skin and (ii) improve skin barrier function and extracellular matrix homeostasis. PMID:26492562

  7. Wound tension in rhytidectomy. Effects of skin-flap undermining and superficial musculoaponeurotic system suspension.

    Science.gov (United States)

    Burgess, L P; Casler, J D; Kryzer, T C

    1993-02-01

    This study was conducted to determine the effects of skin-flap undermining and superficial musculoaponeurotic system (SMAS) suspension on wound-closing tension. Nine sides from five fresh-frozen cadavers were used, with closing tension measured at the two main anchor points, anteriorly (A) and posteriorly (P), with and without SMAS plication for minimal (MIN), intermediate (INT), and maximal (MAX) skin-flap undermining. Results indicated that closing tension was significantly decreased with SMAS plication, both A and P, for all three levels of skin undermining. The average decrease in closing tension with SMAS plication was: A-MIN 191 g, A-INT 95 g, A-MAX 83 g, P-MIN 235 g, P-INT 68 g, and P-MAX 70 g (P tension decreased with wider skin-flap undermining, both with and without SMAS plication. The tension-reducing effect of SMAS plication was decreased with wider skin-flap undermining. Regression analysis determined a second-order exponential curve relating closing tension to skin excision.

  8. Fractional Laser Photothermolysis in the Treatment of Skin Defects: Possibilities and Effectiveness (Review

    Directory of Open Access Journals (Sweden)

    М.М. Karabut

    2016-06-01

    Full Text Available For skin defect treatment and rejuvenation the ablative laser skin resurfacing with a CO2 laser is widely applied in cosmetology and dermatology. However this treatment can result in the risk of undesirable side effects and requires a long-term recovery after the procedure. When non-ablative laser skin rejuvenation is used as an alternative, the level of safety is increased, however the efficacy of the procedure is considerably reduced. The use of fractional laser photothermolysis is a particularly important step in the development of laser technology for cosmetology and dermatology. Due to the creation of only microscopic areas of thermal damage under the laser exposure, this method results in safe, quick healing and complete recovery of the skin without any undesirable side effects. The review presented here illustrate the high efficacy of the application of both ablative and non-ablative fractional laser photothermolysis for wrinkles reduction, for general improvement of the skin appearance, for the abnormal pigmentation treatment, and the removal or appearance improvement of atrophic scars from acne as well as in areas of skin stretching (striae.

  9. Kinetic theory of spin-polarized systems in electric and magnetic fields with spin-orbit coupling. I. Kinetic equation and anomalous Hall and spin-Hall effects

    Science.gov (United States)

    Morawetz, K.

    2015-12-01

    The coupled kinetic equation for density and spin Wigner functions is derived including spin-orbit coupling, electric and magnetic fields, and self-consistent Hartree mean fields suited for SU(2) transport. The interactions are assumed to be with scalar and magnetic impurities as well as scalar and spin-flip potentials among the particles. The spin-orbit interaction is used in a form suitable for solid state physics with Rashba or Dresselhaus coupling, graphene, extrinsic spin-orbit coupling, and effective nuclear matter coupling. The deficiencies of the two-fluid model are worked out consisting of the appearance of an effective in-medium spin precession. The stationary solution of all these systems shows a band splitting controlled by an effective medium-dependent Zeeman field. The self-consistent precession direction is discussed and a cancellation of linear spin-orbit coupling at zero temperature is reported. The precession of spin around this effective direction caused by spin-orbit coupling leads to anomalous charge and spin currents in an electric field. Anomalous Hall conductivity is shown to consist of the known results obtained from the Kubo formula or Berry phases and a symmetric part interpreted as an inverse Hall effect. Analogously the spin-Hall and inverse spin-Hall effects of spin currents are discussed which are present even without magnetic fields showing a spin accumulation triggered by currents. The analytical dynamical expressions for zero temperature are derived and discussed in dependence on the magnetic field and effective magnetizations. The anomalous Hall and spin-Hall effect changes sign at higher than a critical frequency dependent on the relaxation time.

  10. A study of the human skin-whitening effects of resveratryl triacetate.

    Science.gov (United States)

    Ryu, Ja Hyun; Seok, Jin Kyung; An, Sang Mi; Baek, Ji Hwoon; Koh, Jae Sook; Boo, Yong Chool

    2015-04-01

    Resveratrol has a variety of bioactivities that include its anti-melanogenic effects, but its use in cosmetics has been challenging partly because of its chemical instability. Resveratryl triacetate (RTA) is a prodrug that can enhance stability. The purpose of this study was to examine the skin safety and whitening effects of RTA in human subjects. The primary skin irritation potentials of RTA and resveratrol were tested at 0.1 and 0.5 % on human subjects. Resveratrol at a concentration of 0.5 % induced weak skin irritation, whereas RTA did not induce any skin responses. The skin-whitening efficacy of a cosmetic formulation containing 0.4 % RTA was evaluated in two different test models. In the artificial tanning model, the test product and the control product were applied twice daily to the skin of the forearms of 22 human subjects after pigmentation induction by ultraviolet irradiation. Applying the test and the control products to the artificial tanning model for 8 weeks increased the individual topology angles (ITA°) by 17.06 and 13.81 %, respectively, a difference that was statistically significant (p < 0.05). In the hyperpigmentation model, the test product and the control product were applied twice daily to the faces of 21 human subjects. The averaged intensity of the hyperpigmented spots decreased by 2.67 % in the test group and 1.46 % in the control group, a difference that was statistically significant (p < 0.05). Therefore, RTA incorporated into cosmetic formulations can whiten human skin without inducing skin irritation. PMID:25750159

  11. Effects of radioactive hot particles on pig skin

    Energy Technology Data Exchange (ETDEWEB)

    Kaurin, D.G.; Baum, J.W.; Schaefer, C.W. [and others

    1997-06-01

    The purpose of these studies was to determine the incidence and severity of lesions resulting from very localized deposition of dose to skin from small (< 0.5 mm) discrete radioactive particles as produced in the work environments of nuclear reactors. Hanford mini-pigs were exposed, both on a slightly off the skin, to localized replicate doses from 0.31 to 64 Gy (averaged over 1 cm{sup 2} at 70 {mu}m depth unless noted otherwise) using Sc-46, Yb-175, Tm-170, and fissioned UC{sub 2} isotopes having maximum beta-particle energies from about 0.3 to 3 MeV. Erythema and scabs (indicating ulceration) were scored for up to 71 days post-irradiation. The responses followed normal cumulative probability distributions, and therefore, no true threshold could be defined. Hence, 10 and 50% scab incidence rates were deduced using probit analyses. The lowest dose which produced 10% incidence was about 1 Gy for Yb-175 (0.5 MeV maximum energy) beta particle exposures, and about 3 to 9 Gy for other isotopes. The histopathology of lesions was determined at several doses. Single exposures to doses as large as 1,790 Gy were also given, and results were observed for up to 144 days post-exposure. Severity of detriment was estimated by analyzing the results in terms of lesion diameter, persistence, and infection. Over 1,100 sites were exposed. Only two exposed sites became infected after doses near 5000 Gy; the lesions healed quickly on treatment. 105 refs., 145 figs., 47 tabs.

  12. Suppression of the Neoclassical Tearing Modes in Tokamaks under Anomalous Transverse Transport Conditions when the Magnetic Well Effect Predominates over the Bootstrap Drive

    International Nuclear Information System (INIS)

    A study is made of the suppression of neoclassical tearing modes in tokamaks under anomalous transverse transport conditions when the magnetic well effect predominates over the bootstrap drive. It is stressed that the corresponding effect, which is called the compound suppression effect, depends strongly on the profiles of the electron and ion temperature perturbations. Account is taken of the fact that the temperature profile can be established as a result of the competition between anomalous transverse heat transport, on the one hand, and longitudinal collisional heat transport, longitudinal heat convection, longitudinal inertial transport, and transport due to the rotation of magnetic islands, on the other hand. The role of geodesic effects is discussed. The cases of competition just mentioned are described by the model sets of reduced transport equations, which are called, respectively, collisional, convective, inertial, and rotational plasmophysical models. The magnetic well is calculated with allowance for geodesic effects. It is shown that, for strong anomalous heat transport conditions, the contribution of the magnetic well to the generalized Rutherford equation for the island width W is independent of W not only in the collisional model (which has been investigated earlier) but also in the convective and inertial models and depends very weakly (logarithmically) on W in the rotational model. It is this weak dependence that gives rise to the compound effect, which is the subject of the present study. A criterion for the stabilization of neoclassical tearing modes by the compound effect at an arbitrary level of the transverse heat transport by electrons and ions is derived and is analyzed for two cases: when the electron heat transport and ion heat transport are both strong, and when the electron heat transport is strong and the ion heat transport is weak

  13. Evaluation of the effectiveness of wet ice, dry ice, and cryogenic packs in reducing skin temperature.

    Science.gov (United States)

    Belitsky, R B; Odam, S J; Hubley-Kozey, C

    1987-07-01

    The purposes of this study were to evaluate and compare the ability of wet ice (WI), dry ice (DI), and cryogenic packs (CGPs) to reduce and maintain the reduction of skin temperature directly under the cooling agent and to determine whether the cooling effect on skin extended beyond the surface area in contact with the cooling agent. Ten female volunteers participated in the study, and each of the three cold modalities was applied randomly to the skin overlying the right triceps surae muscle. After 15 minutes of cold application, mean skin temperatures recorded under WI, DI, and CGP decreased 12 degrees, 9.9 degrees, and 7.3 degrees C, respectively. The only significant differences in cooling were between WI and DI and between WI and CGP. Fifteen minutes after removal of the cold modalities, no significant differences were found in mean skin temperature between WI, DI, and CGP. The residual mean decrease in skin temperature between the pretreatment rest interval (time 0) and 15 minutes after removal of the cold modality (time 30) was significant for WI only. No cooling was demonstrated 1 cm proximal or distal to any of the cooling agents after 15 minutes of cold application. These findings provide valuable information for the use of cryotherapy in the clinical setting.

  14. Effect of Colorspace Transformation, the Illuminance Component, and Color Modeling on Skin Detection

    Energy Technology Data Exchange (ETDEWEB)

    Jayaram, S; Schmugge, S; Shin, M C; Tsap, L V

    2004-03-22

    Skin detection is an important preliminary process in human motion analysis. It is commonly performed in three steps: transforming the pixel color to a non-RGB colorspace, dropping the illumination component of skin color, and classifying by modeling the skin color distribution. In this paper, we evaluate the effect of these three steps on the skin detection performance. The importance of this study is a new comprehensive colorspace and color modeling testing methodology that would allow for making the best choices for skin detection. Combinations of nine colorspaces, the presence of the absence of the illuminance component, and the two color modeling approaches are compared. The performance is measured by using a receiver operating characteristic (ROC) curve on a large dataset of 805 images with manual ground truth. The results reveal that (1) the absence of the illuminance component decreases performance, (2) skin color modeling has a greater impact than colorspace transformation, and (3) colorspace transformations can improve performance in certain instances. We found that the best performance was obtained by transforming the pixel color to the SCT, HSI, or CIELAB colorspaces, keeping the illuminance component, and modeling the color with the histogram approach.

  15. Insights into bacterial colonization of intensive care patients' skin: the effect of chlorhexidine daily bathing.

    Science.gov (United States)

    Cassir, N; Papazian, L; Fournier, P-E; Raoult, D; La Scola, B

    2015-05-01

    Skin is a major reservoir of bacterial pathogens in intensive care unit (ICU) patients. The aim of this study was to assess the skin bacterial richness and diversity in ICU patients and the effect of CHG daily bathing on skin microbiota. Twenty ICU patients were included during an interventional period with CHG daily bathing (n = 10) and a control period (n = 10). At day seven of hospitalization, eight skin swab samples (nares, axillary vaults, inguinal creases, manubrium and back) were taken from each patient. The bacterial identification was performed by microbial culturomics. We used the Shannon index to compare the diversity. We obtained 5,000 colonies that yielded 61 bacterial species (9.15 ± 3.7 per patient), including 15 (24.5 %) that had never been cultured from non-pathological human skin before, and three (4.9 %) that had never been cultured from human samples before. Notably, Gram-negative bacteria were isolated from all sites. In the water-and-soap group, there was a higher risk of colonization with Gram-negative bacteria (OR = 6.05, 95 % CI [1.67-21.90]; P = 0.006). In the CHG group, we observed more patients colonized by sporulating bacteria (9/10 vs. 3/10; P = 0.019) with a reduced skin bacterial richness (P = 0.004) and lower diversity (0.37, 95 % CI [0.33; 0.42] vs. 0.50, 95 % CI [0.48; 0.52]). Gram-negative bacteria are frequent and disseminated components of the transient skin flora in ICU patients. CHG daily bathing is associated with a reduction in Gram-negative bacteria colonization together with substantial skin microbiota shifts. PMID:25604707

  16. Skin effect mitigation in laser processed multi-walled carbon nanotube/copper conductors

    Energy Technology Data Exchange (ETDEWEB)

    Keramatnejad, K.; Zhou, Y. S.; Gao, Y.; Rabiee Golgir, H.; Wang, M.; Lu, Y. F., E-mail: ylu2@unl.edu [Department of Electrical and Computer Engineering, University of Nebraska-Lincoln, Lincoln, Nebraska 68588-0511 (United States); Jiang, L. [School of Mechanical Engineering, Beijing Institute of Technology, Beijing 100081 (China); Silvain, J.-F. [Institut de Chimie de la Matière Condensée de Bordeaux (ICMCB-CNRS) 87, Avenue du Docteur Albert Schweitzer F-33608 Pessac Cedex (France)

    2015-10-21

    In this study, laser-processed multi-walled carbon nanotube (MWCNT)/Cu conductors are introduced as potential passive components to mitigate the skin effect of Cu at high frequencies (0–10 MHz). Suppressed skin effect is observed in the MWCNT/Cu conductors compared to primitive Cu. At an AC frequency of 10 MHz, a maximum AC resistance reduction of 94% was observed in a MWCNT/Cu conductor after being irradiated at a laser power density of 189 W/cm{sup 2}. The reduced skin effect in the MWCNT/Cu conductors is ascribed to the presence of MWCNT channels which are insensitive to AC frequencies. The laser irradiation process is observed to play a crucial role in reducing contact resistance at the MWCNT-Cu interfaces, removing impurities in MWCNTs, and densifying MWCNT films.

  17. New derivation method and simulation of skin effect in biological tissue.

    Science.gov (United States)

    Fan, Xiaoli; Zhou, Qianxiang; Liu, Zhongqi; Xie, Fang

    2015-01-01

    Based on the electrical properties of biological tissues, bioimpedance measurement technology can be employed to collect physiologic and pathologic information by measuring changes in human bioimpedance. When an alternating current (AC) is applied as a detection signal to a tissue, the current field distribution, which is affected by skin effect, is related to both the bioimpedance of the tissue and the AC frequency. These relations would possibly reduce the accuracy and reliability of the measurement. In this study, an electromagnetic theory-based method, in which cylindrical conductor were divided into layers, was used to obtain current field distribution models of human limbs. Model simulations were conducted in MATLAB. The skin effect phenomenon and its characteristics in human tissues at different frequencies were observed, thus providing essential data on skin effect, which are useful in the development of bioimpedance measurement technology. PMID:26406033

  18. Effects of Cosmetic Formulations Containing Hydroxyacids on Sun-Exposed Skin: Current Applications and Future Developments

    Directory of Open Access Journals (Sweden)

    Andrija Kornhauser

    2012-01-01

    Full Text Available This paper describes recent data on the effects of various skin formulations containing hydroxyacids (HAs and related products on sun-exposed skin. The most frequently used classes of these products, such as α- and β-hydroxyacids, polyhydroxy acids, and bionic acids, are reviewed, and their application in cosmetic formulations is described. Special emphasis is devoted to the safety evaluation of these formulations, particularly on the effects of their prolonged use on sun-exposed skin. We also discuss the important contribution of cosmetic vehicles in these types of studies. Data on the effects of HAs on melanogenesis and tanning are also included. Up-to-date methods and techniques used in those explorations, as well as selected future developments in the cosmetic area, are presented.

  19. Effects of radioactive hot particles on pig skin

    International Nuclear Information System (INIS)

    The purpose of these studies was to determine the incidence and severity of lesions resulting from very localized deposition of dose to skin from small (2 at 70 μm depth unless noted otherwise) using Sc-46, Yb-175, Tm-170, and fissioned UC2 isotopes having maximum beta-particle energies from about 0.3 to 3 MeV. Erythema and scabs (indicating ulceration) were scored for up to 71 days post-irradiation. The responses followed normal cumulative probability distributions, and therefore, no true threshold could be defined. Hence, 10 and 50% scab incidence rates were deduced using probit analyses. The lowest dose which produced 10% incidence was about 1 Gy for Yb-175 (0.5 MeV maximum energy) beta particle exposures, and about 3 to 9 Gy for other isotopes. The histopathology of lesions was determined at several doses. Single exposures to doses as large as 1,790 Gy were also given, and results were observed for up to 144 days post-exposure. Severity of detriment was estimated by analyzing the results in terms of lesion diameter, persistence, and infection. Over 1,100 sites were exposed. Only two exposed sites became infected after doses near 5000 Gy; the lesions healed quickly on treatment. 105 refs., 145 figs., 47 tabs

  20. Vascular effects of leukotriene D4 in human skin

    DEFF Research Database (Denmark)

    Bisgaard, H

    1987-01-01

    in blood flow were confirmed by control estimates of the blood flow rate by a 133xenon washout method. The pressor response to a Valsalva maneuver was reversed by local nerve block, but not affected by LTD4. Therefore LTD4 did not interfere with the sympathetic activity on the cutaneous vessels......Leukotriene D4 (LTD4) increased the blood flow rate in human skin, equipotent to histamine in the dose range of 3.1-200 pmol. The vasodilatation lasted for up to 60 min, and no late reactions occurred. Indomethacin did not affect the LTD4-induced blood flow rate. H1 and H2 antagonists reduced...... the increase in blood flow rate, but did not abolish the response to LTD4. Local nerve block inhibited the axon reflex-mediated flare component of the LTD4-induced blood flow rate, leaving a local red reaction. This local red reaction was not affected by H1 and H2 antagonists. These results indicate histamine...

  1. Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women

    Directory of Open Access Journals (Sweden)

    Watanabe F

    2014-10-01

    Full Text Available Fumiko Watanabe,1 Erika Hashizume,1 Gertrude P Chan,2 Ayako Kamimura11Healthcare Products Development Center, KYOWA HAKKO BIO CO., LTD., Tsukuba, Ibaraki, Japan; 2Clinical Trial Management and Testing Associates, Inc., Filinvest Corporate City, Alabang, Muntinlupa City, PhilippinesPurpose: Glutathione is a tripeptide consisting of cysteine, glycine, and glutamate and functions as a major antioxidant. It is synthesized endogenously in humans. Glutathione protects thiol protein groups from oxidation and is involved in cellular detoxification for maintenance of the cell environment. Reduced glutathione (GSH has a skin-whitening effect in humans through its tyrosinase inhibitory activity, but in the case of oxidized glutathione (GSSG this effect is unclear. We examined the skin-whitening and skin-condition effects of topical GSSG in healthy women.Subjects and methods: The subjects were 30 healthy adult women aged 30 to 50 years. The study design was a randomized, double-blind, matched-pair, placebo-controlled clinical trial. Subjects applied GSSG 2% (weight/weight [w/w] lotion to one side of the face and a placebo lotion to the other side twice daily for 10 weeks. We objectively measured changes in melanin index values, moisture content of the stratum corneum, smoothness, wrinkle formation, and elasticity of the skin. The principal investigator and each subject also used subjective scores to investigate skin whitening, wrinkle reduction, and smoothness. Analysis of variance was used to evaluate differences between groups.Results: The skin melanin index was significantly lower with GSSG treatment than with placebo from the early weeks after the start of the trial through to the end of the study period (at 10 weeks, P<0.001. In addition, in the latter half of the study period GSSG-treated sites had significant increases in moisture content of the stratum corneum, suppression of wrinkle formation, and improvement in skin smoothness. There were no

  2. Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence.

    Science.gov (United States)

    Vaughn, Alexandra R; Branum, Amy; Sivamani, Raja K

    2016-08-01

    Turmeric (Curcuma longa), a commonly used spice throughout the world, has been shown to exhibit antiinflammatory, antimicrobial, antioxidant, and anti-neoplastic properties. Growing evidence shows that an active component of turmeric, curcumin, may be used medically to treat a variety of dermatologic diseases. This systematic review was conducted to examine the evidence for the use of both topical and ingested turmeric/curcumin to modulate skin health and function. The PubMed and Embase databases were systematically searched for clinical studies involving humans that examined the relationship between products containing turmeric, curcumin, and skin health. A total of 234 articles were uncovered, and a total of 18 studies met inclusion criteria. Nine studies evaluated the effects of ingestion, eight studies evaluated the effects of topical, and one study evaluated the effects of both ingested and topical application of turmeric/curcumin. Skin conditions examined include acne, alopecia, atopic dermatitis, facial photoaging, oral lichen planus, pruritus, psoriasis, radiodermatitis, and vitiligo. Ten studies noted statistically significant improvement in skin disease severity in the turmeric/curcumin treatment groups compared with control groups. Overall, there is early evidence that turmeric/curcumin products and supplements, both oral and topical, may provide therapeutic benefits for skin health. However, currently published studies are limited and further studies will be essential to better evaluate efficacy and the mechanisms involved. Copyright © 2016 John Wiley & Sons, Ltd.

  3. Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence.

    Science.gov (United States)

    Vaughn, Alexandra R; Branum, Amy; Sivamani, Raja K

    2016-08-01

    Turmeric (Curcuma longa), a commonly used spice throughout the world, has been shown to exhibit antiinflammatory, antimicrobial, antioxidant, and anti-neoplastic properties. Growing evidence shows that an active component of turmeric, curcumin, may be used medically to treat a variety of dermatologic diseases. This systematic review was conducted to examine the evidence for the use of both topical and ingested turmeric/curcumin to modulate skin health and function. The PubMed and Embase databases were systematically searched for clinical studies involving humans that examined the relationship between products containing turmeric, curcumin, and skin health. A total of 234 articles were uncovered, and a total of 18 studies met inclusion criteria. Nine studies evaluated the effects of ingestion, eight studies evaluated the effects of topical, and one study evaluated the effects of both ingested and topical application of turmeric/curcumin. Skin conditions examined include acne, alopecia, atopic dermatitis, facial photoaging, oral lichen planus, pruritus, psoriasis, radiodermatitis, and vitiligo. Ten studies noted statistically significant improvement in skin disease severity in the turmeric/curcumin treatment groups compared with control groups. Overall, there is early evidence that turmeric/curcumin products and supplements, both oral and topical, may provide therapeutic benefits for skin health. However, currently published studies are limited and further studies will be essential to better evaluate efficacy and the mechanisms involved. Copyright © 2016 John Wiley & Sons, Ltd. PMID:27213821

  4. Effect of local allergen priming on early, late, delayed-phase, and epicutaneous skin reactions

    NARCIS (Netherlands)

    Weller, FR; Weller, MS; Jansen, HM; deMonchy, JGR

    1996-01-01

    Allergic disease is renected in a chronic inflammatory response to an allergen. It is thought that local allergen priming underlies this chronicity. To assess the effect of allergen priming on the amplitude and histologic effect of the allergic reaction, four sequential, intracutaneous skin tests we

  5. Transient performances analysis of wind turbine system with induction generator including flux saturation and skin effect

    DEFF Research Database (Denmark)

    Li, H.; Zhao, B.; Han, L.;

    2010-01-01

    In order to analyze correctly the effect of different models for induction generators on the transient performances of large wind power generation, Wind turbine driven squirrel cage induction generator (SCIG) models taking into account both main and leakage flux saturation and skin effect were pr...

  6. Fermi surface versus Fermi sea contributions to intrinsic anomalous and spin Hall effects of multiorbital metals in the presence of Coulomb interaction and spin-Coulomb drag

    Science.gov (United States)

    Arakawa, Naoya

    2016-06-01

    Anomalous Hall effect (AHE) and spin Hall effect (SHE) are fundamental phenomena, and their potential for application is great. However, we understand the interaction effects unsatisfactorily, and should have clarified issues about the roles of the Fermi sea term and Fermi surface term of the conductivity of the intrinsic AHE or SHE of an interacting multiorbital metal and about the effects of spin-Coulomb drag on the intrinsic SHE. Here, we resolve the first issue and provide the first step about the second issue by developing a general formalism in the linear response theory with appropriate approximations and using analytic arguments. The most striking result is that even without impurities, the Fermi surface term, a non-Berry-curvature term, plays dominant roles at high or slightly low temperatures. In particular, this Fermi surface term causes the temperature dependence of the dc anomalous Hall or spin Hall conductivity due to the interaction-induced quasiparticle damping and the correction of the dc spin Hall conductivity due to the spin-Coulomb drag. Those results revise our understanding of the intrinsic AHE and SHE. We also find that the differences between the dc anomalous Hall and longitudinal conductivities arise from the difference in the dominant multiband excitations. This not only explains why the Fermi sea term such as the Berry-curvature term becomes important in clean and low-temperature case only for interband transports, but also provides the useful principles on treating the electron-electron interaction in an interacting multiorbital metal for general formalism of transport coefficients. Several correspondences between our results and experiments are finally discussed.

  7. The Skindex instruments to measure the effects of skin disease on quality of life.

    Science.gov (United States)

    Chren, Mary-Margaret

    2012-04-01

    Skindex-29 and Skindex-16 are validated measures of the effects of skin diseases on patients' quality of life. This article reviews the development of both versions of Skindex, discusses their measurement properties and interpretability, and gives examples of how they have been used and adapted for dermatologic research internationally. Studies of quality of life in patients with nonmelanoma skin cancer are described to illustrate the use of Skindex to understand quality of life and to compare effectiveness of different treatments for this highly prevalent condition. PMID:22284137

  8. The charmonium dissociation in an "anomalous wind"

    CERN Document Server

    Sadofyev, Andrey V

    2016-01-01

    We study the charmonium dissociation in a strongly coupled chiral plasma in the presence of magnetic field and axial charge imbalance. This type of plasma carries ``anomalous flow" induced by the chiral anomaly and exhibits novel transport phenomena such as chiral magnetic effect. We found that the ``anomalous flow" would modify the charmonium color screening length by using the gauge/gravity correspondence. We derive an analytical expression quantifying the ``anomalous flow" experienced by a charmonium for a large class of chiral plasma with a gravity dual. We elaborate on the similarity and {\\it qualitative} difference between anomalous effects on the charmonium color screening length which are {\\it model-dependent} and those on the heavy quark drag force which are fixed by the second law of thermodynamics. We speculate on the possible charmonium dissociation induced by chiral anomaly in heavy ion collisions.

  9. Mechanistic effects of long-term ultraviolet B irradiation induce epidermal and dermal changes in human skin xenografts.

    Science.gov (United States)

    Hachiya, Akira; Sriwiriyanont, Penkanok; Fujimura, Tsutomu; Ohuchi, Atsushi; Kitahara, Takashi; Takema, Yoshinori; Kitzmiller, William J; Visscher, Marty O; Tsuboi, Ryoji; Boissy, Raymond E

    2009-02-01

    UVB irradiation has been reported to induce photoaging and suppress systemic immune function that could lead to photocarcinogenesis. However, because of the paucity of an UVB-induced photodamaged skin model, precise and temporal mechanism(s) underlying the deleterious effects of long-term UVB exposure on human skin have yet to be delineated. In this study, we established a model using human skin xenografted onto severe combined immunodeficient mice, which were subsequently challenged by repeated UVB irradiation for 6 weeks. Three-dimensional optical image analysis of skin replicas and noninvasive biophysical measurements illustrated a significant increase in skin surface roughness, similar to premature photoaging, and a significant loss of skin elasticity after long-term UVB exposure. Resembling authentically aged skin, UVB-exposed samples exhibited significant increases in epithelial keratins (K6, K16, K17), elastins, and matrix metalloproteinases (MMP-1, MMP-9, MMP-12) as well as degradation of collagens (I, IV, VII). The UVB-induced deterioration of fibrous keratin intermediate filaments was also observed in the stratum corneum. Additionally, similarities in gene expression patterns between our model and chronologically aged skin substantiated the plausible relationship between photodamage and chronological age. Furthermore, severe skin photodamage was observed when neutralizing antibodies against TIMP-1, an endogenous inhibitor of MMPs, were administered during the UVB exposure regimen. Taken together, these findings suggest that our skin xenograft model recapitulates premature photoaged skin and provides a comprehensive tool with which to assess the deleterious effects of UVB irradiation.

  10. Application of the Aqueous Porous Pathway Model to Quantify the Effect of Sodium Lauryl Sulfate on Ultrasound-Induced Skin Structural Perturbation

    OpenAIRE

    Polat, Baris E.; Seto, Jennifer E.; Blankschtein, Daniel; Langer, Robert

    2010-01-01

    This study investigated the effect of sodium lauryl sulfate (SLS) on skin structural perturbation when utilized simultaneously with low-frequency sonophoresis (LFS). Pig full-thickness skin (FTS) and pig split-thickness skin (STS) treated with LFS/SLS and LFS were analyzed in the context of the aqueous porous pathway model to quantify skin perturbation through changes in skin pore radius and porosity-to-tortuosity ratio (ε/τ). In addition, skin treatment times required to attain specific leve...

  11. The vasorelaxant effect of adrenomedullin, proadrenomedullin N-terminal 20 peptide and amylin in human skin

    DEFF Research Database (Denmark)

    Hasbak, Philip; Eskesen, Karen; Lind, Peter Henrik;

    2006-01-01

    of the peptides. The mRNA expression was assessed by real-time reverse transcriptase-polymerase chain reaction (real-time PCR). CGRP, adrenomedullin and amylin induced concentration-dependent, long-lasting increases in skin blood flow. The response to PAMP was shorter in duration appearing similar......In this study we aimed to assess in vivo, the vasodilator effects of adrenomedullin, proadrenomedullin N-terminal 20 peptide (PAMP) and amylin in human skin vasculature and compare the responses to the effects mediated by the endogenous neuropeptides calcitonin gene-related peptide (CGRP......) and substance P and to examine the mRNA expression of calcitonin receptor-like receptor (CL-R) and receptor-activity modifying proteins, RAMP1, RAMP 2 and RAMP3 in human subcutaneous arteries. Changes in skin blood flow of the forearm were measured using a Laser Doppler Imager after intradermal injection...

  12. Transcriptomic analysis of bottlenose dolphin (Tursiops truncatus) skin biopsies to assess the effects of emerging contaminants.

    Science.gov (United States)

    Lunardi, Denise; Abelli, Luigi; Panti, Cristina; Marsili, Letizia; Fossi, Maria Cristina; Mancia, Annalaura

    2016-03-01

    Chemicals discovered in water at levels that may be significantly different than expected are referred to as contaminants of emerging concern (CECs) because the risk to environmental health posed by their occurrence/frequency is still unknown. The worldwide distributed compounds perfluorooctanoic acid (PFOA) and bisphenol A (BPA) may fall into this category due to effects on endocrine receptors. We applied an ex vivo assay using small slices of bioptic skin from the bottlenose dolphin, Tursiops truncatus, cultured and treated for 24 h with different PFOA or BPA concentrations to analyze global gene expression. RNA was labeled and hybridized to a species-specific oligomicroarray. The skin transcriptome held information on the contaminant exposure, potentially predictive about long-term effects on health, being the genes affected involved in immunity modulation, response to stress, lipid homeostasis, and development. The transcriptomic signature of dolphin skin could be therefore relevant as classifier for a specific contaminant. PMID:26794494

  13. Effect of compositions in nanostructured lipid carriers (NLC on skin hydration and occlusion

    Directory of Open Access Journals (Sweden)

    Loo CH

    2012-12-01

    Full Text Available CH Loo,1,2 M Basri,2 R Ismail,1 HLN Lau,1 BA Tejo,2 MS Kanthimathi,3 HA Hassan,1 YM Choo11Malaysian Palm Oil Board, Bandar Baru Bangi, 2Department of Chemistry, Universiti Putra Malaysia, Serdang, 3Department of Molecular Medicine, University of Malaya, Kuala Lumpur, MalaysiaPurpose: To study the effects of varying lipid concentrations, lipid and oil ratio, and the addition of propylene glycol and lecithin on the long-term physical stability of nanostructured lipid nanocarriers (NLC, skin hydration, and transepidermal water loss.Methods: The various NLC formulations (A1–A5 were prepared and their particle size, zeta potential, viscosity, and stability were analyzed. The formulations were applied on the forearms of the 20 female volunteers (one forearm of each volunteer was left untreated as a control. The subjects stayed for 30 minutes in a conditioned room with their forearms uncovered to let the skin adapt to the temperature (22°C ± 2°C and humidity (50% ± 2% of the room. Skin hydration and skin occlusion were recorded at day one (before treatment and day seven (after treatment. Three measurements for skin hydration and skin occlusion were performed in each testing area.Results: NLC formulations with the highest lipid concentration, highest solid lipid concentration, and additional propylene glycol (formulations A1, A2, and A5 showed higher physical stability than other formulations. The addition of propylene glycol into an NLC system helped to reduce the particle size of the NLC and enhanced its long-term physical stability. All the NLC formulations were found to significantly increase skin hydration compared to the untreated controls within 7 days. All NLC formulations exhibited occlusive properties as they reduced the transepidermal water loss within 7 days. This effect was more pronounced with the addition of propylene glycol or lecithin into an NLC formulation, whereby at least 60% reduction in transepidermal water loss was observed

  14. Anomalous transport due to scale anomaly

    CERN Document Server

    Chernodub, M N

    2016-01-01

    We show that the scale anomaly in field theories leads to new anomalous transport effects that emerge in external electromagnetic field in inhomogeneous gravitational background. In inflating geometry the QED scale anomaly generates electric current which flows in opposite direction with respect to background electric field. In static spatially inhomogeneous gravitational background the dissipationless electric current flows transversely both to the magnetic field axis and to the gradient of the inhomogeneity. The anomalous currents are proportional to the beta function of the theory.

  15. Scaling of the anomalous Hall effect in epitaxial antiperovskite Mn3.5Dy0.5N involving multiple competing scattering mechanisms

    Science.gov (United States)

    Meng, M.; Wu, S. X.; Zhou, W. Q.; Li, S. W.

    2016-08-01

    Anomalous Hall effect (AHE) has been studied for ferrimagnetic antiperovskite Mn3.5Dy0.5N film grown by molecular-beam epitaxy. Reflective high energy electron diffraction and transmission electron microscopy demonstrate the high quality of the film. We have used a scaling involving multiple competing scattering mechanisms to distinguish variations of contributions to the AHE by heavily doped Dy. The scaling analysis revealed that the heavily doped Dy has dramatically modified the skew scattering part of the AHE in Mn4N and Mn3.5Dy0.5N has a totally different scattering mechanism from an undoped film.

  16. Skin cooling aids cerebrovascular function more effectively under severe than moderate heat stress.

    Science.gov (United States)

    Lucas, Rebekah A I; Ainslie, Philip N; Fan, Jui-Lin; Wilson, Luke C; Thomas, Kate N; Cotter, James D

    2010-05-01

    Skin surface cooling has been shown to improve orthostatic tolerance; however, the influence of severe heat stress on cardiovascular and cerebrovascular responses to skin cooling remains unknown. Nine healthy males, resting supine in a water-perfusion suit, were heated to +1.0 and +2.0 degrees C elevation in body core temperature (T (c)). Blood flow velocity in the middle cerebral artery (transcranial Doppler ultrasound), mean arterial pressure (MAP; photoplethysmography), stroke volume (SV; Modelflow), total peripheral resistance (TPR; Modelflow), heart rate (HR; ECG) and the partial pressure of end-tidal carbon dioxide (P(ET)CO(2)) were measured continuously during 1-min baseline and 3-min lower body negative pressure (LBNP, -15 mm Hg) when heated without and again with skin surface cooling. Nine participants tolerated +1 degrees C and six participants reached +2 degrees C. Skin cooling elevated (P = 0.004) MAP ~4% during baseline and LBNP at +1 degrees C T (c). During LBNP, skin cooling increased SV (9%; P = 0.010) and TPR (0.9 mm Hg L(-1) min, P = 0.013) and lowered HR (13 b min(-1), P = 0.012) at +1 degrees C T (c) and +2 degrees C T (c) collectively. At +2 degrees C T (c), skin cooling elevated P(ET)CO(2) ~4.3 mm Hg (P = 0.011) and therefore reduced cerebral vascular resistance ~0.1 mm Hg cm(-1) s at baseline and LBNP (P = 0.012). In conclusion, skin cooling under severe heating and mild orthostatic stress maintained cerebral blood flow more effectively than it did under moderate heating, in conjunction with elevated carbon dioxide pressure, SV and arterial resistance. PMID:19946700

  17. Effects of magnolol on UVB-induced skin cancer development in mice and its possible mechanism of action

    OpenAIRE

    Chilampalli Chandeshwari; Guillermo Ruth; Zhang Xiaoying; Kaushik Radhey S; Young Alan; Zeman David; Hildreth Michael B; Fahmy Hesham; Dwivedi Chandradhar

    2011-01-01

    Abstract Background Magnolol, a plant lignan isolated from the bark and seed cones of Magnolia officinalis, has been shown to have chemopreventive effects on chemically-induced skin cancer development. The objectives of this investigation are to study the anticarcinogenic effects of magnolol on UVB-induced skin tumor development in SKH-1 mice, a model relevant to humans, and determine the possible role of apoptosis and cell cycle arrest involved in the skin tumor development. Methods UVB-indu...

  18. Anti-obesity effect of resveratrol-amplified grape skin extracts on 3T3-L1 adipocytes differentiation

    OpenAIRE

    Zhang, Xian-Hua; Huang, Bo; Choi, Soo-Kyong; Seo, Jung-Sook

    2012-01-01

    Resveratrol (3,4,5-trihydroxy-trans-stilbene), a phytoalexin found in grape skin, grape products, and peanuts as well as red wine, has been reported to have various biological and pharmacological properties. The purpose of this study was to investigate the anti-obesity effect of resveratrol-amplified grape skin extracts on adipocytes. The anti-obesity effects of grape skin extracts were investigated by measuring proliferation and differentiation in 3T3-L1 cells. The effect of grape skin ethan...

  19. Large power factor and anomalous Hall effect and their correlation with observed linear magneto resistance in Co-doped Bi2Se3 3D topological insulator

    Science.gov (United States)

    Singh, Rahul; Shukla, K. K.; Kumar, A.; Okram, G. S.; Singh, D.; Ganeshan, V.; Lakhani, Archana; Ghosh, A. K.; Chatterjee, Sandip

    2016-09-01

    Magnetoresistance (MR), thermo power, magnetization and Hall effect measurements have been performed on Co-doped Bi2Se3 topological insulators. The undoped sample shows that the maximum MR as a destructive interference due to a π-Berry phase leads to a decrease of MR. As the Co is doped, the linearity in MR is increased. The observed MR of Bi2Se3 can be explained with the classical model. The low temperature MR behavior of Co doped samples cannot be explained with the same model, but can be explained with the quantum linear MR model. Magnetization behavior indicates the establishment of ferromagnetic ordering with Co doping. Hall effect data also supports the establishment of ferromagnetic ordering in Co-doped Bi2Se3 samples by showing the anomalous Hall effect. Furthermore, when spectral weight suppression is insignificant, Bi2Se3 behaves as a dilute magnetic semiconductor. Moreover, the maximum power factor is observed when time reversal symmetry (TRS) is maintained. As the TRS is broken the power factor value is decreased, which indicates that with the rise of Dirac cone above the Fermi level the anomalous Hall effect and linearity in MR increase and the power factor decreases.

  20. Large power factor and anomalous Hall effect and their correlation with observed linear magneto resistance in Co-doped Bi2Se3 3D topological insulator.

    Science.gov (United States)

    Singh, Rahul; Shukla, K K; Kumar, A; Okram, G S; Singh, D; Ganeshan, V; Lakhani, Archana; Ghosh, A K; Chatterjee, Sandip

    2016-09-21

    Magnetoresistance (MR), thermo power, magnetization and Hall effect measurements have been performed on Co-doped Bi2Se3 topological insulators. The undoped sample shows that the maximum MR as a destructive interference due to a π-Berry phase leads to a decrease of MR. As the Co is doped, the linearity in MR is increased. The observed MR of Bi2Se3 can be explained with the classical model. The low temperature MR behavior of Co doped samples cannot be explained with the same model, but can be explained with the quantum linear MR model. Magnetization behavior indicates the establishment of ferromagnetic ordering with Co doping. Hall effect data also supports the establishment of ferromagnetic ordering in Co-doped Bi2Se3 samples by showing the anomalous Hall effect. Furthermore, when spectral weight suppression is insignificant, Bi2Se3 behaves as a dilute magnetic semiconductor. Moreover, the maximum power factor is observed when time reversal symmetry (TRS) is maintained. As the TRS is broken the power factor value is decreased, which indicates that with the rise of Dirac cone above the Fermi level the anomalous Hall effect and linearity in MR increase and the power factor decreases. PMID:27419361

  1. The effects of sulfur mustard exposure and freezing on transdermal penetration of tritiated water through ex vivo pig skin.

    Science.gov (United States)

    Payne, O J; Graham, S J; Dalton, C H; Spencer, P M; Mansson, R; Jenner, J; Azeke, J; Braue, E

    2013-02-01

    The percutaneous absorption of tritiated water ((3)H(2)O) through sulfur mustard (SM) exposed abdominal pig skin was measured using in vitro Franz-type static diffusion cells. The barrier function to water permeation following exposure to liquid SM for 8 min and excision 3h later did not change significantly. A small, but statistically significant difference (P<0.05) in steady state penetration (Jss), permeability coefficient (Kp) and lag time (t(L)) of (3)H(2)O was observed between fresh skin and skin stored frozen (-20 °C) for up to two weeks. Steady-state penetration and Kp values were significantly higher (P < 0.05) in skin stored frozen compared with fresh skin. Fresh naïve skin had an average Kp of 1.65 × 10(-3) cm h(-1), whereas frozen naïve skin was 2.04 × 10(-3) cm h(-1). Fresh SM exposed skin had a mean Kp of 1.72 × 10(-3) cm h(-1), whereas frozen SM exposed skin was 2.31 × 10(-3) cm h(-1). Lag times were also shorter (P<0.05) in skin that had been stored frozen. Frozen, SM-exposed porcine abdominal skin may be used for in vitro penetration studies, but effects of treatment and storage on the barrier layer should be taken into account. PMID:23041075

  2. Titanium Dioxide Nanoparticle Penetration into the Skin and Effects on HaCaT Cells.

    Science.gov (United States)

    Crosera, Matteo; Prodi, Andrea; Mauro, Marcella; Pelin, Marco; Florio, Chiara; Bellomo, Francesca; Adami, Gianpiero; Apostoli, Pietro; De Palma, Giuseppe; Bovenzi, Massimo; Campanini, Marco; Filon, Francesca Larese

    2015-08-07

    Titanium dioxide nanoparticles (TiO2NPs) suspensions (concentration 1.0 g/L) in synthetic sweat solution were applied on Franz cells for 24 h using intact and needle-abraded human skin. Titanium content into skin and receiving phases was determined. Cytotoxicity (MTT, AlamarBlue(®) and propidium iodide, PI, uptake assays) was evaluated on HaCat keratinocytes after 24 h, 48 h, and seven days of exposure. After 24 h of exposure, no titanium was detectable in receiving solutions for both intact and damaged skin. Titanium was found in the epidermal layer after 24 h of exposure (0.47 ± 0.33 μg/cm(2)) while in the dermal layer, the concentration was below the limit of detection. Damaged skin, in its whole, has shown a similar concentration (0.53 ± 0.26 μg/cm(2)). Cytotoxicity studies on HaCaT cells demonstrated that TiO2NPs induced cytotoxic effects only at very high concentrations, reducing cell viability after seven days of exposure with EC50s of 8.8 × 10(-4) M (MTT assay), 3.8 × 10(-5) M (AlamarBlue(®) assay), and 7.6 × 10(-4) M (PI uptake, index of a necrotic cell death). Our study demonstrated that TiO2NPs cannot permeate intact and damaged skin and can be found only in the stratum corneum and epidermis. Moreover, the low cytotoxic effect observed on human HaCaT keratinocytes suggests that these nano-compounds have a potential toxic effect at the skin level only after long-term exposure.

  3. Titanium Dioxide Nanoparticle Penetration into the Skin and Effects on HaCaT Cells

    Directory of Open Access Journals (Sweden)

    Matteo Crosera

    2015-08-01

    Full Text Available Titanium dioxide nanoparticles (TiO2NPs suspensions (concentration 1.0 g/L in synthetic sweat solution were applied on Franz cells for 24 h using intact and needle-abraded human skin. Titanium content into skin and receiving phases was determined. Cytotoxicity (MTT, AlamarBlue® and propidium iodide, PI, uptake assays was evaluated on HaCat keratinocytes after 24 h, 48 h, and seven days of exposure. After 24 h of exposure, no titanium was detectable in receiving solutions for both intact and damaged skin. Titanium was found in the epidermal layer after 24 h of exposure (0.47 ± 0.33 μg/cm2 while in the dermal layer, the concentration was below the limit of detection. Damaged skin, in its whole, has shown a similar concentration (0.53 ± 0.26 μg/cm2. Cytotoxicity studies on HaCaT cells demonstrated that TiO2NPs induced cytotoxic effects only at very high concentrations, reducing cell viability after seven days of exposure with EC50s of 8.8 × 10−4 M (MTT assay, 3.8 × 10−5 M (AlamarBlue® assay, and 7.6 × 10−4 M (PI uptake, index of a necrotic cell death. Our study demonstrated that TiO2NPs cannot permeate intact and damaged skin and can be found only in the stratum corneum and epidermis. Moreover, the low cytotoxic effect observed on human HaCaT keratinocytes suggests that these nano-compounds have a potential toxic effect at the skin level only after long-term exposure.

  4. Development of effective skin cancer treatment and prevention in xeroderma pigmentosum.

    Science.gov (United States)

    Lambert, W Clark; Lambert, Muriel W

    2015-01-01

    Xeroderma pigmentosum (XP) is a rare, recessively transmitted genetic disease characterized by increasingly marked dyspigmentation and xerosis (dryness) of sun-exposed tissues, especially skin. Skin cancers characteristically develop in sun-exposed sites at very much earlier ages than in the general population; these are often multiple and hundreds or even thousands may develop. Eight complementation groups have been identified. Seven groups, XP-A…G, are associated with defective genes encoding proteins involved in the nucleotide excision DNA repair (NER) pathway that recognizes and excises mutagenic changes induced in DNA by sunlight; the eighth group, XP-V, is associated with defective translesion synthesis (TLS) bypassing such alterations. The dyspigmentation, xerosis and eventually carcinogenesis in XP patients appear to be due to their cells' failure to respond properly to these mutagenic DNA alterations, leading to mutations in skin cells. A subset of cases, especially those in some complementation groups, may develop neurological degeneration, which may be severe. However, in most XP patients, in the past the multiple skin cancers have led to death at an early age due to either metastases or sepsis. Using either topical 5-fluorouracil or imiquimod, we have developed a protocol that effectively prevents most skin cancer development in XP patients. PMID:25382223

  5. Effects of niacin restriction on sirtuin and PARP responses to photodamage in human skin.

    Directory of Open Access Journals (Sweden)

    Claudia A Benavente

    Full Text Available Sirtuins (SIRTs and poly(ADP-ribose polymerases (PARPs, NAD(+-dependent enzymes, link cellular energy status with responses to environmental stresses. Skin is frequently exposed to the DNA damaging effects of UV irradiation, a known etiology in skin cancer. Thus, understanding the defense mechanisms in response to UV, including the role of SIRTs and PARPs, may be important in developing skin cancer prevention strategies. Here, we report expression of the seven SIRT family members in human skin. SIRTs gene expressions are progressively upregulated in A431 epidermoid carcinoma cells (SIRTs1 and 3, actinic keratoses (SIRTs 2, 3, 5, 6, and 7 and squamous cell carcinoma (SIRTs 1-7. Photodamage induces dynamic changes in SIRT expression with upregulation of both SIRT1 and SIRT4 mRNAs. Specific losses of SIRT proteins occur early after photodamage followed by accumulation later, especially for SIRT4. Niacin restriction, which decreases NAD(+, the sirtuin substrate, results in an increase in acetylated proteins, upregulation of SIRTs 2 and 4, increased inherent DNA damage, alterations in SIRT responses to photodamage, abrogation of PARP activation following photodamage, and increased sensitivity to photodamage that is completely reversed by repleting niacin. These data support the hypothesis that SIRTs and PARPs play important roles in resistance to photodamage and identify specific SIRTs that respond to photodamage and may be targets for skin cancer prevention.

  6. THERAPEUTIC EFFECT OF SOLASODINE RHAMNOSYL GLYCOSIDES FOR LARGE SKIN CANCERS: TWO CLINICAL CASES

    Directory of Open Access Journals (Sweden)

    Bill E. Cham

    2012-01-01

    Full Text Available Solasodine rhamnosyl glycosides (BEC are a new class of antineoplastics, the efficiency of which administered via intravenous, intraperitoneal, and intratumoral routes is higher than that of many other antitumor agents. Early investigations have established the efficiency of topical BEC applications as a treatment option for non-melanoma skin cancers. There have recently been two clinical cases that count in favor of the fact that the cream formulation Curaderm containing BEC has a very high efficacy in the treatment of large non-melanoma skin cancers that are incurable by other existing methods. Also, Curaderm treatment shows a splendid cosmetic effect

  7. Effects of all-trans retinoic acid and Ca++ on human skin in organ culture.

    OpenAIRE

    Varani, J.; Fligiel, S. E.; Schuger, L; Perone, P.; Inman, D.; Griffiths, C E; Voorhees, J. J.

    1993-01-01

    In this study, we have established an organ culture model of human skin and examined the effects of both all-trans retinoic acid (RA) and extracellular Ca++ on the epidermal and dermal components of the organ-cultured skin. Our data show that while organ cultures maintained in serum-free, growth factor-free culture medium containing 0.15 mM Ca++ degenerated rapidly, those treated with concentrations of RA that have been shown previously to stimulate fibroblast and keratinocyte proliferation i...

  8. The expression of KRT2 and its effect on melanogenesis in alpaca skins.

    Science.gov (United States)

    Cui, Yucong; Song, Yajun; Geng, Qingling; Ding, Zengfeng; Qin, Yilong; Fan, Ruiwen; Dong, Changsheng; Geng, Jianjun

    2016-06-01

    In order to investigate the effects of the keratin 2 (KRT2) on alpaca melanocyte in vivo and vitro, the immunohistochemistry (IHC), quantitative real-time PCR (qPCR), Western blot, and alpaca melanocytes transfection methods were used. The results showed that mRNA and protein expression of KRT2 was highly expressed in brown skin in comparison with that in white skin. Moreover, we found that KRT2 was expressed in alpaca melanocytes in vitro by immunocytochemistry. After transfection with KRT2 in alpaca melanocytes, the relative mRNA and protein expression of KRT2, microphthalmia-associtated transcription factor (MITF), tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1) in alpaca skin melanocytes was increased with significant differences; a further result was the increase of melanin production. The results suggested that KRT2 functions in alpaca hair color formation, which offered an essential theoretical basis for further exploration of the role of melanogenesis. PMID:27265811

  9. Functional behavior of the anomalous magnetic relaxation observed in melt-textured YBa2Cu3O7-δ samples showing the paramagnetic Meissner effect

    Science.gov (United States)

    Dias, F. T.; Vieira, V. N.; Garcia, E. L.; Wolff-Fabris, F.; Kampert, E.; Gouvêa, C. P.; Schaf, J.; Obradors, X.; Puig, T.; Roa, J. J.

    2016-10-01

    We have studied the functional behavior of the field-cooled (FC) magnetic relaxation observed in melt-textured YBa2Cu3O7-δ (Y123) samples with 30 wt% of Y2Ba1Cu1O5 (Y211) phase, in order to investigate anomalous paramagnetic moments observed during the experiments. FC magnetic relaxation experiments were performed under controlled conditions, such as cooling rate and temperature. Magnetic fields up to 5T were applied parallel to the ab plane and along the c-axis. Our results are associated with the paramagnetic Meissner effect (PME), characterized by positive moments during FC experiments, and related to the magnetic flux compression into the samples. After different attempts our experimental data could be adequately fitted by an exponential decay function with different relaxation times. We discuss our results suggesting the existence of different and preferential flux dynamics governing the anomalous FC paramagnetic relaxation in different time intervals. This work is one of the first attempts to interpret this controversial effect in a simple analysis of the pinning mechanisms and flux dynamics acting during the time evolution of the magnetic moment. However, the results may be useful to develop models to explain this interesting and still misunderstood feature of the paramagnetic Meissner effect.

  10. Temperature effect on the static behaviour of adhesively-bonded metal skin to composite stiffener

    NARCIS (Netherlands)

    Teixeira De Freitas, S.; Sinke, J.

    2015-01-01

    The purpose of this research is to study the effect of temperature on the static behavior of an hybrid structure consisting of adhesively bonded Fiber Metal Laminate skin to a composite stiffener. This hybrid structure was tested using stiffener pull-off tests, which is a typical set-up used to simu

  11. High School Students' Perceptions of How Major Global Environmental Effects Might Cause Skin Cancer.

    Science.gov (United States)

    Boyes, Edward; Stanisstreet, Martin

    1998-01-01

    Quantifies beliefs of high school students about links between skin cancer and global environmental effects. Some students confused the action of heat rays with that of ultraviolet rays and also thought that raised temperatures are culpable. Only one in 10 held the scientifically correct model: that ozone depletion via higher penetration of…

  12. The effects of sodium oxybate on core body and skin temperature regulation in narcolepsy

    NARCIS (Netherlands)

    Heide, A. van der; Donjacour, C.E.; Pijl, H.; Reijntjes, R.H.; Overeem, S.; Lammers, G.J.; Someren, E.J.W. van; Fronczek, R.

    2015-01-01

    Patients suffering from narcolepsy type 1 show altered skin temperatures, resembling the profile that is related to sleep onset in healthy controls. The aim of the present study is to investigate the effects of sodium oxybate, a widely used drug to treat narcolepsy, on the 24-h profiles of temperatu

  13. Nonspecific vasodilatation during transdermal iontophoresis—the effect of voltage over the skin

    NARCIS (Netherlands)

    Droog, E.J.; Sjöberg, F.

    2003-01-01

    We used laser Doppler perfusion imaging (LDPI) to study nonspecific vasodilatation during iontophoresis. In iontophoresis studies, nonspecific vasodilatation occurs as a result either of galvanic currents or of the applied voltage over the skin. We made dose–response measurements to study the effect

  14. Pulse testing in the presence of wellbore storage and skin effects

    Energy Technology Data Exchange (ETDEWEB)

    Ogbe, D.O.; Brigham, W.E.

    1984-08-01

    A pulse test is conducted by creating a series of short-time pressure transients in an active (pulsing) well and recording the observed pressure response at an observation (responding) well. Using the pressure response and flow rate data, the transmissivity and storativity of the tested formation can be determined. Like any other pressure transient data, the pulse-test response is significantly influenced by wellbore storage and skin effects. The purpose of this research is to examine the influence of wellbore storage and skin effects on interference testing in general and on pulse-testing in particular, and to present the type curves and procedures for designing and analyzing pulse-test data when wellbore storage and skin effects are active at either the responding well or the pulsing well. A mathematical model for interference testing was developed by solving the diffusivity equation for radial flow of a single-phase, slightly compressible fluid in an infinitely large, homogeneous reservoir. When wellbore storage and skin effects are present in a pulse test, the observed response amplitude is attenuated and the time lag is inflated. Consequently, neglecting wellbore storage and skin effects in a pulse test causes the calculated storativity to be over-estimated and the transmissivity to be under-estimated. The error can be as high as 30%. New correlations and procedures are developed for correcting the pulse response amplitude and time lag for wellbore storage effects. Using these correlations, it is possible to correct the wellbore storage-dominated response amplitude and time lag to within 3% of their expected values without wellbore storage, and in turn to calculate the corresponding transmissivity and storativity. Worked examples are presented to illustrate how to use the new correction techniques. 45 references.

  15. Therapeutic effect of ethyl acetate extract from Asparagus cochinchinensis on phthalic anhydride-induced skin inflammation.

    Science.gov (United States)

    Sung, Ji-Eun; Lee, Hyun-Ah; Kim, Ji-Eun; Go, Jun; Seo, Eun-Ji; Yun, Woo-Bin; Kim, Dong-Seob; Son, Hong-Joo; Lee, Chung-Yeoul; Lee, Hee-Seob; Hwang, Dae-Youn

    2016-03-01

    Asparagus cochinchinensis has been used to treat various diseases including fever, cough, kidney disease, breast cancer, inflammatory disease and brain disease, while IL-4 cytokine has been considered as key regulator on the skin homeostasis and the predisposition toward allergic skin inflammation. However, few studies have investigated its effects and IL-4 correlation on skin inflammation to date. To quantitatively evaluate the suppressive effects of ethyl acetate extracts of A. cochinchinensis (EaEAC) on phthalic anhydride (PA)-induced skin inflammation and investigate the role of IL-4 during their action mechanism, alterations in general phenotype biomarkers and luciferase-derived signals were measured in IL-4/Luc/CNS-1 transgenic (Tg) mice with PA-induced skin inflammation after treatment with EaEAC for 2 weeks. Key phenotype markers including lymph node weight, immunoglobulin E (IgE) concentration, epidermis thickness and number of infiltrated mast cells were significantly decreased in the PA+EaEAC treated group compared with the PA+Vehicle treated group. In addition, expression of IL-1β and TNF-α was also decreased in the PA+EaEAC cotreated group, compared to PA+Vehicle treated group. Furthermore, a significant decrease in the luciferase signal derived from IL-4 promoter was detected in the abdominal region, submandibular lymph node and mesenteric lymph node of the PA+EaEAC treated group, compared to PA+Vehicle treated group. Taken together, these results suggest that EaEAC treatment could successfully improve PA-induced skin inflammation of IL-4/Luc/CNS-1 Tg mice, and that IL-4 cytokine plays a key role in the therapeutic process of EaEAC. PMID:27051441

  16. Studies on the protection effects of functional foods for skin immune system from radiation damage

    International Nuclear Information System (INIS)

    We evaluated the protective effects of pilot products (HemoHIM and HemoTonic) on the UV-induced skin immune damages as the following. · Protective effects of HemoHIM and HemoTonic against UV using contact hypersensitivity model - Protection against depression of contact hypersensitivity by administration and skin application of HemoHIM and HemoTonic - Induction of dendritic cell differentiation and maturation by HemoHIM and HemoTonic treatment - Improvement of antigen-presenting activity of dedritic cells by HemoHIM and HemoTonic treatment · Protective effects of HemoHIM and HemoTonic on skin immune system against UV-irradiation - Protection of antigen-presenting activity of dendritic cells under UV-irradiation - In vivo protection of antigen-presenting activity of Langerhans cells in UV-irradiated mice · Protective effects of HemoHIM on UV-induced apoptosis of dendritic cells - Inhibition of cell membrane change, mitochondrial potential change, SubG1 cell population, nuclear condensation, and DNA fragmentation in UV-irradiated dendritic cells · Anti-allergic effects of HemoHIM and HemoTonic in human adipocyte HMC-1 cells - Inhibition of allergic histamine release from adipocytes - Inhibition of secretion of inflammatory cytokines (IL-6, IL-8, TNF-α, GM-CSF) - Inhibition of c-kit, tryptase, FcεRI mRNA expression From these results, the developed functional food products (HemoHIM, HemoTonic) showed the protection and recovery of the immune functions in the UV-irradiated skin. It is suggested that these products may be used as a new functional food or cosmetic material for the protection of skin damage and the promotion of recovery

  17. Skin penetration and antioxidant effect of cosmeto-textiles with gallic acid.

    Science.gov (United States)

    Alonso, C; Martí, M; Barba, C; Lis, M; Rubio, L; Coderch, L

    2016-03-01

    In this work, the antioxidant gallic acid (GA) has been encapsulated in microspheres prepared with poly-ε-caprolactone (PCL) and incorporated into polyamide (PA) obtaining the cosmeto-textile. The topical application of the cosmeto-textile provides a reservoir effect in the skin delivery of GA. The close contact of the cosmeto-textile, containing microsphere-encapsulated GA (ME-GA), with the skin and their corresponding occlusion, may be the main reasons that explain the crossing of active principle (GA) through the skin barrier, located in the stratum corneum, and its penetration into the different compartments of the skin, epidermis and dermis. An ex vivo assessment was performed to evaluate the antioxidant effect of the ME-GA on the stratum corneum (SC) using the thiobarbituric acid-reactive species (TBARS) test. The test is based on a non-invasive ex vivo methodology that evaluates lipid peroxides formed in the outermost layers of the SC from human volunteers after UV radiation to determine the effectiveness of an antioxidant. In this case, a ME-GA cosmeto-textile or ME-GA formulation were applied to the skin in vivo and lipid peroxidation (LPO) in the horny layer were determined after UV irradiation. This methodology may be used as a quality control tool to determine ex vivo the percentage of LPO inhibition on human SC for a variety of antioxidants that are topically applied, in this case GA. Results show that LPO formation was inhibited in human SC when GA was applied directly or embedded in the cosmeto-textile, demonstrating the effectiveness of both applications. The percentage of LPO inhibition obtained after both topical applications was approximately 10% for the cosmeto-textile and 41% for the direct application of microspheres containing GA. This methodology could be used to determine the effectiveness of topically applied antioxidants encapsulated in cosmeto-textiles on human SC.

  18. Studies on the protection effects of functional foods for skin immune system from radiation damage

    Energy Technology Data Exchange (ETDEWEB)

    Yee, Sung Tae; Shin, Seong Hae; Kim, Do Sun; Heo, Ji Yun; Kang, Hye In [Sunchon National University, Sunchon (Korea, Republic of)

    2007-07-15

    We evaluated the protective effects of pilot products (HemoHIM and HemoTonic) on the UV-induced skin immune damages as the following. centre dot Protective effects of HemoHIM and HemoTonic against UV using contact hypersensitivity model - Protection against depression of contact hypersensitivity by administration and skin application of HemoHIM and HemoTonic - Induction of dendritic cell differentiation and maturation by HemoHIM and HemoTonic treatment - Improvement of antigen-presenting activity of dedritic cells by HemoHIM and HemoTonic treatment centre dot Protective effects of HemoHIM and HemoTonic on skin immune system against UV-irradiation - Protection of antigen-presenting activity of dendritic cells under UV-irradiation - In vivo protection of antigen-presenting activity of Langerhans cells in UV-irradiated mice centre dot Protective effects of HemoHIM on UV-induced apoptosis of dendritic cells - Inhibition of cell membrane change, mitochondrial potential change, SubG1 cell population, nuclear condensation, and DNA fragmentation in UV-irradiated dendritic cells centre dot Anti-allergic effects of HemoHIM and HemoTonic in human adipocyte HMC-1 cells - Inhibition of allergic histamine release from adipocytes - Inhibition of secretion of inflammatory cytokines (IL-6, IL-8, TNF-alpha, GM-CSF) - Inhibition of c-kit, tryptase, FcepsilonRI mRNA expression From these results, the developed functional food products (HemoHIM, HemoTonic) showed the protection and recovery of the immune functions in the UV-irradiated skin. It is suggested that these products may be used as a new functional food or cosmetic material for the protection of skin damage and the promotion of recovery

  19. Skin penetration and antioxidant effect of cosmeto-textiles with gallic acid.

    Science.gov (United States)

    Alonso, C; Martí, M; Barba, C; Lis, M; Rubio, L; Coderch, L

    2016-03-01

    In this work, the antioxidant gallic acid (GA) has been encapsulated in microspheres prepared with poly-ε-caprolactone (PCL) and incorporated into polyamide (PA) obtaining the cosmeto-textile. The topical application of the cosmeto-textile provides a reservoir effect in the skin delivery of GA. The close contact of the cosmeto-textile, containing microsphere-encapsulated GA (ME-GA), with the skin and their corresponding occlusion, may be the main reasons that explain the crossing of active principle (GA) through the skin barrier, located in the stratum corneum, and its penetration into the different compartments of the skin, epidermis and dermis. An ex vivo assessment was performed to evaluate the antioxidant effect of the ME-GA on the stratum corneum (SC) using the thiobarbituric acid-reactive species (TBARS) test. The test is based on a non-invasive ex vivo methodology that evaluates lipid peroxides formed in the outermost layers of the SC from human volunteers after UV radiation to determine the effectiveness of an antioxidant. In this case, a ME-GA cosmeto-textile or ME-GA formulation were applied to the skin in vivo and lipid peroxidation (LPO) in the horny layer were determined after UV irradiation. This methodology may be used as a quality control tool to determine ex vivo the percentage of LPO inhibition on human SC for a variety of antioxidants that are topically applied, in this case GA. Results show that LPO formation was inhibited in human SC when GA was applied directly or embedded in the cosmeto-textile, demonstrating the effectiveness of both applications. The percentage of LPO inhibition obtained after both topical applications was approximately 10% for the cosmeto-textile and 41% for the direct application of microspheres containing GA. This methodology could be used to determine the effectiveness of topically applied antioxidants encapsulated in cosmeto-textiles on human SC. PMID:26848532

  20. Effect of Prayer and “OM” Meditation in Enhancing Galvanic Skin Response

    Directory of Open Access Journals (Sweden)

    Ira Das

    2012-10-01

    Full Text Available The research was conducted with the purpose to study the effect of prayer and meditation on galvanic skin response (GSR. It was hypothesized that there was a significant positive effect of prayer and meditation (Om chanting on galvanic skin response (GSR. The sample consisted of 20 normal, healthy female participants through purposive sampling. The age group of the sample was 18 to 24 years (Mean= 18.7, SD= 1.55. Gender was female and minimum education was graduation. The daily practice time of prayer and meditation session was 30 minutes for one month. Pre- Post data were recorded before and after intervention of prayer and meditation session by using single group pre-post research design. Recordings of galvanic skin response (GSR were made on a computerized polygraph (Model Physiopac, PP 4, Medicaid Systems, Chandigarh, India test. The results revealed a significant increase in GSR values as an effect of prayer and meditation which suggested the psychophysiological relaxation. Practicing prayer and meditation increases the galvanic skin response and hence decreases the stress level of the individual.

  1. Effect of cyclic aromatics on sodium active transport in frog skin

    Energy Technology Data Exchange (ETDEWEB)

    Blankemeyer, J.T.; Bowerman, M.C. (Oklahoma State Univ., Stillwater (United States))

    1993-01-01

    A modified glass Ussing-chamber was used to mount the skin. The electrical potential difference (PD) was measured by two 3% agar-frog Ringer's bridges. Current (i.e. short-circuit current, or ISC) was passed by Ag-AgCl electrodes placed so that current density was uniform across the skin. Ringer's solution, bathing each side of the frog skin, was stirred and aerated by gas-lift pumps. The effect of toxicants on the ISC was determined by using the 15 min prior to toxicant administration as a control period, then calculating the change in ISC during the toxicant period as a percent of the control ISC. Phenol and benzene are components of crude oil and crude oil waste. These hydrocarbons and phenanthrene were tested for their effect on frog skin. The results show that the effect of organics on sodium active transport of an epithelium is to alter the active transport of sodium ions. 5 refs., 3 figs., 1 tab.

  2. Effects of wall temperature on skin-friction measurements by oil-film interferometry

    International Nuclear Information System (INIS)

    Wind-tunnel skin-friction measurements with thin-oil-film interferometry have been taken on an aluminum sample to investigate the effects of wall temperature on the accuracy of the technique. The sample has been flush-mounted onto a flat plate with an electric heater at its bottom and mirror-smooth temperature-sensitive paint sprayed on its top. The heater has varied the sample temperature from ambient to 328 K, and the paint has permitted wall temperature measurements on the same area of the skin-friction measurements and during the same test. The measured wall temperatures have been used to calculate the correct oil viscosities, and these viscosities and the constant nominal viscosity at 298 K have been used to calculate two different sets of skin-friction coefficients. These sets have been compared to each other and with theoretical values. This comparison shows that the effects of wall temperature on the accuracy of skin-friction measurements are sensible, and more so as wall temperature differs from 298 K. Nonetheless, they are effectively neutralized by the use of wall temperature measurements in combination with the correct oil viscosity–temperature law. In this regard, the special temperature-sensitive paint developed for this study shows advantages with respect to more traditional wall temperature measurement techniques. (paper)

  3. Measuring the effects of topically applied skin optical clearing agents and modeling the effects and consequences for laser therapies

    Science.gov (United States)

    Verkruysse, Wim; Khan, Misbah; Choi, Bernard; Svaasand, Lars O.; Nelson, J. Stuart

    2005-04-01

    Human skin prepared with an optical clearing agent manifests reduced scattering as a result of de-hydration and refractive index matching. This has potentially large effects for laser therapies of several skin lesions such as port wine stain, hair removal and tattoo removal. With most topically applied clearing agents the clearing effect is limited because they penetrate poorly through the intact superficial skin layer (stratum corneum). Agent application modi other than topical are impractical and have limited the success of optical clearing in laser dermatology. In recent reports, however, a mixture of lipofylic and hydrofylic agents was shown to successfully penetrate through the intact stratum corneum layer which has raised new interest in this field. Immediately after application, the optical clearing effect is superficial and, as the agent diffuses through the skin, reduced scattering is manifested in deeper skin layers. For practical purposes as well as to maximize therapeutic success, it is important to quantify the reduced scattering as well as the trans-cutaneous transport dynamics of the agent. We determined the time and tissue depth resolved effects of optically cleared skin by inserting a microscopic reflector array in the skin. Depth dependent light intensity was measured by quantifying the signal of the reflector array with optical coherence tomography. A 1-dimensional mass diffusion model was used to estimate a trans-cutaneous transport diffusion constant for the clearing agent mixture. The results are used in Monte Carlo modeling to determine the optimal time of laser treatment after topical application of the optical clearing agent.

  4. Hydrodynamic function of biomimetic shark skin: effect of denticle pattern and spacing.

    Science.gov (United States)

    Wen, Li; Weaver, James C; Thornycroft, Patrick J M; Lauder, George V

    2015-12-01

    The structure of shark skin has been the subject of numerous studies and recently biomimetic shark skin has been fabricated with rigid denticles (scales) on a flexible substrate. This artificial skin can bend and generate thrust when attached to a mechanical controller. The ability to control the manufacture of biomimetic shark skin facilitates manipulation of surface parameters and understanding the effects of changing denticle patterns on locomotion. In this paper we investigate the effect of changing the spacing and arrangement of denticles on the surface of biomimetic shark skin on both static and dynamic locomotor performance. We designed 3D-printed flexible membranes with different denticle patterns and spacings: (1) staggered-overlapped, (2) linear-overlapped, and (3) linear-non-overlapped, and compared these to a 3D-printed smooth-surfaced control. These 3D printed shark skin models were then tested in a flow tank with a mechanical flapping device that allowed us to either hold the models in a stationary position or move them dynamically. We swam the membranes at a frequency of 1 Hz with different heave amplitudes (from ±1 cm to ±3 cm) while measuring forces, torques, self-propelled swimming speed, and cost of transport (COT). Static tests revealed drag reduction of denticle patterns compared to a smooth control at low speeds, but increased drag at speeds above 25 cm s(-1). However, during dynamic (swimming) tests, the staggered-overlapped pattern produced the fastest swimming speeds with no significant increase in the COT at lower heave values. For instance, at a heave frequency of 1 Hz and amplitude of ±1 cm, swimming speed of the staggered-overlapped pattern increased by 25.2% over the smooth control. At higher heave amplitudes, significantly faster self-propelled swimming speeds were achieved by the staggered-overlapped pattern, but with higher COT. Only the staggered-overlapped pattern provides a significant swimming performance advantage over the

  5. Hydrodynamic function of biomimetic shark skin: effect of denticle pattern and spacing.

    Science.gov (United States)

    Wen, Li; Weaver, James C; Thornycroft, Patrick J M; Lauder, George V

    2015-11-18

    The structure of shark skin has been the subject of numerous studies and recently biomimetic shark skin has been fabricated with rigid denticles (scales) on a flexible substrate. This artificial skin can bend and generate thrust when attached to a mechanical controller. The ability to control the manufacture of biomimetic shark skin facilitates manipulation of surface parameters and understanding the effects of changing denticle patterns on locomotion. In this paper we investigate the effect of changing the spacing and arrangement of denticles on the surface of biomimetic shark skin on both static and dynamic locomotor performance. We designed 3D-printed flexible membranes with different denticle patterns and spacings: (1) staggered-overlapped, (2) linear-overlapped, and (3) linear-non-overlapped, and compared these to a 3D-printed smooth-surfaced control. These 3D printed shark skin models were then tested in a flow tank with a mechanical flapping device that allowed us to either hold the models in a stationary position or move them dynamically. We swam the membranes at a frequency of 1 Hz with different heave amplitudes (from ±1 cm to ±3 cm) while measuring forces, torques, self-propelled swimming speed, and cost of transport (COT). Static tests revealed drag reduction of denticle patterns compared to a smooth control at low speeds, but increased drag at speeds above 25 cm s(-1). However, during dynamic (swimming) tests, the staggered-overlapped pattern produced the fastest swimming speeds with no significant increase in the COT at lower heave values. For instance, at a heave frequency of 1 Hz and amplitude of ±1 cm, swimming speed of the staggered-overlapped pattern increased by 25.2% over the smooth control. At higher heave amplitudes, significantly faster self-propelled swimming speeds were achieved by the staggered-overlapped pattern, but with higher COT. Only the staggered-overlapped pattern provides a significant swimming performance advantage over the

  6. Characterization of atopic skin and the effect of a hyperforin-rich cream by laser scanning microscopy

    Science.gov (United States)

    Meinke, Martina C.; Richter, Heike; Kleemann, Anke; Lademann, Juergen; Tscherch, Kathrin; Rohn, Sascha; Schempp, Christoph M.

    2015-05-01

    Atopic dermatitis (AD) is a multifactorial inflammatory skin disease that affects both children and adults in an increasing manner. The treatment of AD often reduces subjective skin parameters, such as itching, dryness, and tension, but the inflammation cannot be cured. Laser scanning microscopy was used to investigate the skin surface, epidermal, and dermal characteristics of dry and atopic skin before and after treatment with an ointment rich in hyperforin, which is known for its anti-inflammatory effects. The results were compared to subjective parameters and transepidermal water loss, stratum corneum moisture, and stratum corneum lipids. Using biophysical methods, in particular laser scanning microscopy, it was found that atopic skin has distinct features compared to healthy skin. Treatment with a hyperforin-rich ointment resulted in an improvement of the stratum corneum moisture, skin surface dryness, skin lipids, and the subjective skin parameters, indicating that the barrier is stabilized and improved by the ointment. But in contrast to the improved skin surface, the inflammation in the deeper epidermis/dermis often continues to exist. This could be clearly shown by the reflectance confocal microscopy (RCM) measurements. Therefore, RCM measurements could be used to investigate the progress in treatment of atopic dermatitis.

  7. Anomalous law of cooling

    Science.gov (United States)

    Lapas, Luciano C.; Ferreira, Rogelma M. S.; Rubí, J. Miguel; Oliveira, Fernando A.

    2015-03-01

    We analyze the temperature relaxation phenomena of systems in contact with a thermal reservoir that undergoes a non-Markovian diffusion process. From a generalized Langevin equation, we show that the temperature is governed by a law of cooling of the Newton's law type in which the relaxation time depends on the velocity autocorrelation and is then characterized by the memory function. The analysis of the temperature decay reveals the existence of an anomalous cooling in which the temperature may oscillate. Despite this anomalous behavior, we show that the variation of entropy remains always positive in accordance with the second law of thermodynamics.

  8. Anomalous law of cooling

    International Nuclear Information System (INIS)

    We analyze the temperature relaxation phenomena of systems in contact with a thermal reservoir that undergoes a non-Markovian diffusion process. From a generalized Langevin equation, we show that the temperature is governed by a law of cooling of the Newton’s law type in which the relaxation time depends on the velocity autocorrelation and is then characterized by the memory function. The analysis of the temperature decay reveals the existence of an anomalous cooling in which the temperature may oscillate. Despite this anomalous behavior, we show that the variation of entropy remains always positive in accordance with the second law of thermodynamics

  9. Anomalous law of cooling

    Energy Technology Data Exchange (ETDEWEB)

    Lapas, Luciano C., E-mail: luciano.lapas@unila.edu.br [Universidade Federal da Integração Latino-Americana, Caixa Postal 2067, 85867-970 Foz do Iguaçu, Paraná (Brazil); Ferreira, Rogelma M. S., E-mail: rogelma.maria@gmail.com [Centro de Ciências Exatas e Tecnológicas, Universidade Federal do Recôncavo da Bahia, 44380-000 Cruz das Almas, Bahia (Brazil); Rubí, J. Miguel, E-mail: mrubi@ub.edu [Departament de Física Fonamental, Facultat de Física, Universitat de Barcelona, Av. Diagonal 647, 08028 Barcelona (Spain); Oliveira, Fernando A., E-mail: fernando.oliveira@pq.cnpq.br [Instituto de Física and Centro Internacional de Física da Matéria Condensada, Universidade de Brasília, Caixa Postal 04513, 70919-970 Brasília, Distrito Federal (Brazil)

    2015-03-14

    We analyze the temperature relaxation phenomena of systems in contact with a thermal reservoir that undergoes a non-Markovian diffusion process. From a generalized Langevin equation, we show that the temperature is governed by a law of cooling of the Newton’s law type in which the relaxation time depends on the velocity autocorrelation and is then characterized by the memory function. The analysis of the temperature decay reveals the existence of an anomalous cooling in which the temperature may oscillate. Despite this anomalous behavior, we show that the variation of entropy remains always positive in accordance with the second law of thermodynamics.

  10. Modeling the Substrate Skin Effects in Mutual RL Characteristics.,

    Directory of Open Access Journals (Sweden)

    D. de Roest

    2003-12-01

    Full Text Available The goal of this work was to model the influence of the substrateskin effects on the distributed mutual impedance per unit lengthparameters of multiple coupled on-chip interconnects. The proposedanalytic model is based on the frequency-dependent distribution of thecurrent in the silicon substrate and the closed form integrationapproach. It is shown that the calculated frequency-dependentdistributed mutual inductance and the associated mutual resistance arein good agreement with the results obtained from CAD-oriented circuitmodeling technique.

  11. The Effects of Advertising Strategies on Consumer Trust: A Case of Skin Care Products in Taiwan

    Directory of Open Access Journals (Sweden)

    Velly Anatasia

    2016-09-01

    Full Text Available The main aim of this study was to develop advertising strategies in order to increase consumer trust. Four advertising elements, celebrity endorsement, branding, product attribute, and third party certification, were investigated in this study. Data were collected to answer two research questions: (1 To investigate the advertising strategies of skin care products leading to consumer trust, (2 To know the effects of advertising strategies in skin care products on consumer trust. A 5-point Likert scale survey was distributed to the female population in Taipei area. Via online and personal approaches, 266 questionnaires were returned. Targeting on 18-30 years old female skin care product users who stay in Taipei area more than six months, 240 qualified questionnaires were analyzed. The four independent variables are found having a significant relationship with trust in skin care advertising, in which branding has the greatest influence on increasing consumer trust. The control variable which is financial status is not found having statistically significant effect on consumer trust. To conclude, this study is dedicated to the communities in order to optimize their marketing strategies.

  12. Sunscreens: topical and systemic approaches for protection of human skin against harmful effects of solar radiation

    International Nuclear Information System (INIS)

    This review deals with topical and systemic approaches for protection of human skin against the harmful effects of solar radiation. Two concerns about the deleterious effects of sun exposure involve: (1) acute effects (e.g., sunburn and drug-induced phototoxicity) and (2) potential long-term risks of repeated sun exposures leading to development of solar elastosis, keratoses, induction of both nonmelanoma and melanoma skin cancer, and alteration of immune responses and functions. Action spectra of normal and abnormal reactions of human skin to acute and chronic effects of solar radiation are presented with a view to helping the physician prescribe the appropriate sunscreens. Factors that influence acute effects of sunburn are reviewed. Various artificial methods effective in minimizing or preventing harmful effects of solar radiation, both in normal individuals and in patients with photosensitivity-related problems, are discussed. Emphasis is placed on the commercially available chemical sunscreens and their properties. Sun protection factor (SPF) values of several brand-name formulations determined with a solar simulator under indoor conditions (laboratory) and with solar radiation under natural, field conditions are presented. Factors responsible for variations of SPF values observed under indoor and outdoor conditions are reviewed. Systemic photoprotective agents and their limitations are outlined. The photobiology of melanin pigmentation (the tanning reaction) is briefly discussed, with emphasis on the dangers of using quick-tanning lotions for stimulation of the tanning reaction

  13. Effects of sarpogrelate hydrochloride on skin ulcers and quality of life in patients with systemic sclerosis.

    Science.gov (United States)

    Yoshimasu, Takashi; Ikeda, Takaharu; Uede, Koji; Kanazawa, Nobuo; Furukawa, Fukumi

    2012-06-01

    5-Hydroxytryptamine 2A serotonin receptor (5-HT(2A) ) is associated with the contraction of vascular smooth muscle, platelet aggregation and thrombus formation and coronary artery spasms. Sarpogrelate hydrochloride (sarpogrelate) is a selective 5-HT(2A) antagonist and was supposed to be effective for Raynaud's phenomenon with collagen disease. Sarpogrelate has not been investigated regarding the effects, safety and quality of life (QOL) in patient with skin ulcers of collagen disease. Eleven patients with skin ulcers and systemic sclerosis (SSc) were administrated sarpogrelate p.o. three times a day for 3-6 months. The area (mean ± standard error) of skin ulcer at the pretreatment, and after 3 and 6 months of sarpogrelate intake was 2.1 ± 0.8, 0.2 ± 0.1 and 0.1 ± 0.1 mm(2), respectively. The reduction of skin ulcer area was significant after 3 months of sarpogrelate intake. In assessment of QOL, scores of symptoms and emotions but not of functioning were significantly improved after sarpogrelate intake. The global score (mean ± SE) of Skindex-16 at pretreatment, and after 3 and 6 months of sarpogrelate intake was 31.8 ± 8.7, 23.7 ± 8.3 and 10.9 ± 4.6, respectively. The score was significantly improved after 6 months of sarpogrelate intake. There were no obvious side-effects during this study. Sarpogrelate was considered to be a useful drug to improve skin ulcers and QOL in patients with SSc. PMID:22077618

  14. Modeling skin effect in large magnetized iron detectors

    International Nuclear Information System (INIS)

    The experimental problem of the calibration of magnetic field in large iron detectors is discussed. Emphasis is laid on techniques based on ballistic measurements as the ones employed by MINOS or OPERA. In particular, we provide analytical formulas to model the behavior of the apparatus in the transient regime, keeping into account eddy current effects and the finite penetration velocity of the driving fields. These formulas ease substantially the design of the calibration apparatus. Results are compared with experimental data coming from a prototype of the OPERA spectrometer

  15. Modeling skin effect in large magnetized iron detectors

    CERN Document Server

    Incurvati, M

    2003-01-01

    The experimental problem of the calibration of magnetic field in large iron detectors is discussed. Emphasis is laid on techniques based on ballistic measurements as the ones employed by MINOS or OPERA.In particular, we provide analytical formulas to model the behavior of the apparatus in the transient regime, keeping into account eddy current effects and the finite penetration velocity of the driving fields. These formulas ease substantially the design of the calibration apparatus.Results are compared with experimental data coming from a prototype of the OPERA spectrometer.

  16. ttH anomalous coupling in double Higgs production

    International Nuclear Information System (INIS)

    We study the effects of top-Higgs anomalous coupling in the production of a pair of Higgs boson via gluon fusion at the Large Hadron Collider (LHC). The introduction of anomalous ttH coupling can alter the hadronic double Higgs boson cross section and can lead to characteristic changes in certain kinematic distributions. We perform a global analysis based on available LHC data on the Higgs to constrain the parameters of ttH anomalous coupling. Possible overlap of the predictions due to anomalous ttH coupling with those due to anomalous trilinear Higgs coupling is also studied. We briefly discuss the effect of the anomalous ttH coupling on the HZ production via gluon fusion which is one of the main backgrounds in the HH→γγbb-macron channel

  17. Cultured skin fibroblasts from patients with porokeratosis are hypersensitive to the lethal effects of X-radiation

    International Nuclear Information System (INIS)

    Porokeratosis is an autosomal dominant inherited skin disorder. The lesions are characterized by localized abnormal keratinization and may develop into malignant tumors. To determine the cellular basis of the cancer susceptibility associated with this skin condition, we examined the colony-forming ability of X-ray or ultraviolet (UV) light irradiated, cultured fibroblasts derived from porokeratosis patients' normal-appearing skin. Four fibroblast strains derived from four porokeratosis patients' skin were significantly hypersensitive to the lethal effects of X-radiation. However, they all showed a similar sensitivity to strains from normal donors to 254 nm UV light. The hypersensitivity to X-ray radiation in cultured skin fibroblasts from porokeratosis patients suggests an inherent instability of cellular DNA and may prbably be associated with the cancer-prone nature of this skin condition. (author)

  18. Partial oxidation of Step-Bound Water Leads to Anomalous pH Effects on Metal Electrode Step-Edges

    CERN Document Server

    Schwarz, Kathleen; Yan, Yushan; Sundararaman, Ravishankar

    2016-01-01

    The design of better heterogeneous catalysts for applications such as fuel cells and electrolyzers requires a mechanistic understanding of electrocatalytic reactions and the dependence of their activity on operating conditions such as pH. A satisfactory explanation for the unexpected pH dependence of electrochemical properties of platinum surfaces has so far remained elusive, with previous explanations resorting to complex co-adsorption of multiple species and resulting in limited predictive power. This knowledge gap suggests that the fundamental properties of these catalysts are not yet understood, limiting systematic improvement. Here, we analyze the change in charge and free energies upon adsorption using density-functional theory (DFT) to establish that water adsorbs on platinum step edges across a wide voltage range, including the double-layer region, with a loss of approximately 0.2 electrons upon adsorption. We show how the change in net surface charge due to this water explains the anomalous pH variat...

  19. Synergistic effects of green tea and ginkgo biloba extracts on the improvement of skin barrier function and elasticity.

    Science.gov (United States)

    Campos, Patricia M B G Maia; Gianeti, Mirela D; Mercurio, Daiane G; Gaspar, Lorena R

    2014-09-01

    This study aimed to evaluate the effects of cosmetic formulations containing green tea (GT) and/or Ginkgo biloba (GB) extracts by preclinical and clinical studies. For the preclinical study, histological analysis was performed after 5 day-period of formulations application on the dorsum of hairless mice. For the clinical study, the formulations were applied on the forearm skin of 48 volunteers, and assessed before and after 3 hours and after a 15 and 30 day-period of application. Histological analysis showed that the formulation with GT (FGT) and the association of GT and GB (FBlend) significantly enhanced viable epidermis thickness and the number of cell layers, suggesting a moisturizing effect in skin deeper layers and increased cell renewal. The clinical efficacy studies showed that the extracts had a moisturizing effect and improved skin microrelief. In addition they synergistically acted on the skin elasticity and skin barrier function. In conclusion, the formulation containing a combination of green tea and Ginkgo biloba extracts effectively improved skin conditions and the effect of formulation FBlend on the improvement of skin elasticity was more pronounced. Finally, the results of the present study revealed other important clinical benefits of Ginkgo biloba and green tea extracts on the skin besides their already known antioxidant action.

  20. Synergistic effects of green tea and ginkgo biloba extracts on the improvement of skin barrier function and elasticity.

    Science.gov (United States)

    Campos, Patricia M B G Maia; Gianeti, Mirela D; Mercurio, Daiane G; Gaspar, Lorena R

    2014-09-01

    This study aimed to evaluate the effects of cosmetic formulations containing green tea (GT) and/or Ginkgo biloba (GB) extracts by preclinical and clinical studies. For the preclinical study, histological analysis was performed after 5 day-period of formulations application on the dorsum of hairless mice. For the clinical study, the formulations were applied on the forearm skin of 48 volunteers, and assessed before and after 3 hours and after a 15 and 30 day-period of application. Histological analysis showed that the formulation with GT (FGT) and the association of GT and GB (FBlend) significantly enhanced viable epidermis thickness and the number of cell layers, suggesting a moisturizing effect in skin deeper layers and increased cell renewal. The clinical efficacy studies showed that the extracts had a moisturizing effect and improved skin microrelief. In addition they synergistically acted on the skin elasticity and skin barrier function. In conclusion, the formulation containing a combination of green tea and Ginkgo biloba extracts effectively improved skin conditions and the effect of formulation FBlend on the improvement of skin elasticity was more pronounced. Finally, the results of the present study revealed other important clinical benefits of Ginkgo biloba and green tea extracts on the skin besides their already known antioxidant action. PMID:25226010

  1. Effects of Bezafibrate on the Survival of Random Skin Flaps in Rats.

    Science.gov (United States)

    Lin, Bin; Lin, Yuting; Lin, Dingsheng; Cao, Bin

    2016-06-01

    Background Bezafibrate is widely used in clinics for its comparable angiogenic effect. Our research is to investigate the effect of bezafibrate on random skin flap survival. Materials and Methods The "McFarlane flap" rat models were established in 30 male Sprague-Dawley rats which were divided into two groups. The treatment group was given bezafibrate (400 mg/kg/day; gavage administration), and the control group received the vehicle. The flap surviving area was measured after 7 days, and the tissue samples were taken for histological analysis and edema measurement. Vascular endothelial growth factor (VEGF) was determined using immunohistochemical methods. Superoxide dismutase (SOD) activity and malondialdehyde (MDA) content were examined with kits. Results Seven days after the operation, the surviving area in the treatment group was larger than in the control group (p Bezafibrate improves the survival of random skin flaps effectively. PMID:26872027

  2. Effects of Nicotinamide on Mouse Skin Tumor Development and lts Mode of Action

    Institute of Scientific and Technical Information of China (English)

    KRISHNA P. GUPTA

    1999-01-01

    Nicotinamide (NA), a naturally occuring vitamin and a protease inhibitor, has been shown to be effective in treating some skin ailments. It inhibits cell proliferation and induces cell differentiation. This report shows the effects of NA on mouse skin tumor development and on the critical events involved in this process. NA reduced tumor growth, inhibited the 12-O-tetradecanoylphorbol- 13-acetate (TPA) induced ornithine decarboxylase activity, but induced the transglutaminase activity which was inhibited by TPA under different experimental conditions.The effects of NA on ornithine decarboxylase (ODC) and transglutaminase (TG) indicated that nicotinamide (NA) probably programmmed the cells for their death in the natural course of time, I.e. Programed cell death. This observation indicates that NA might be a better agent for the detailed study and for the better use in prevention of cancer alone or in combination with other drugs.

  3. Anomalous pion decay revisited

    CERN Document Server

    Battistel, O A; Nemes, M C; Hiller, B

    1999-01-01

    An implicit four dimensional regularization is applied to calculate the axial-vector-vector anomalous amplitude. The present technique always complies with results of Dimensional Regularization and can be easily applied to processes involving odd numbers of $\\gamma_5$ matrices. This is illustrated explicitely in the example of this letter.

  4. Effect of Red Clover Isoflavones over Skin, Appendages, and Mucosal Status in Postmenopausal Women

    Directory of Open Access Journals (Sweden)

    Markus Lipovac

    2011-01-01

    Full Text Available Objective. Evaluate in postmenopausal women the effect of red clover extract (RCE isoflavones over subjective status of skin, appendages, and several mucosal sites. Method. Postmenopausal women (n=109 were randomly assigned to receive either two daily capsules of the active compound (80 mg RCE, Group A or placebo of equal appearance (Group B for a 90-day period. After a washout period of 7 days, medication was crossed over and taken for 90 days more. Subjective improvement of skin, appendages, and several mucosal site status was assessed for each studied group at 90 and 187 days using a visual analogue scale (VAS. In addition, libido, tiredness, and urinary, sleep, and mood complaints were also evaluated. Results. Women after RCE intervention (both groups reported better subjective improvement of scalp hair and skin status, libido, mood, sleep, and tiredness. Improvement of urinary complaints, nail, body hair, and mucosa (oral, nasal, and ocular status did not differ between treatment phases (intra- and intergroup. Overall satisfaction with treatment was reported higher after RCE intervention (both groups as compared to placebo. Conclusion. RCE supplementation exerted a subject improvement of scalp hair and skin status as well as libido, mood, sleep, and tiredness in postmenopausal women.

  5. Effect of Red Clover Isoflavones over Skin, Appendages, and Mucosal Status in Postmenopausal Women

    Science.gov (United States)

    Lipovac, Markus; Chedraui, Peter; Gruenhut, Christine; Gocan, Anca; Kurz, Christine; Neuber, Benedikt; Imhof, Martin

    2011-01-01

    Objective. Evaluate in postmenopausal women the effect of red clover extract (RCE) isoflavones over subjective status of skin, appendages, and several mucosal sites. Method. Postmenopausal women (n = 109) were randomly assigned to receive either two daily capsules of the active compound (80 mg RCE, Group A) or placebo of equal appearance (Group B) for a 90-day period. After a washout period of 7 days, medication was crossed over and taken for 90 days more. Subjective improvement of skin, appendages, and several mucosal site status was assessed for each studied group at 90 and 187 days using a visual analogue scale (VAS). In addition, libido, tiredness, and urinary, sleep, and mood complaints were also evaluated. Results. Women after RCE intervention (both groups) reported better subjective improvement of scalp hair and skin status, libido, mood, sleep, and tiredness. Improvement of urinary complaints, nail, body hair, and mucosa (oral, nasal, and ocular) status did not differ between treatment phases (intra- and intergroup). Overall satisfaction with treatment was reported higher after RCE intervention (both groups) as compared to placebo. Conclusion. RCE supplementation exerted a subject improvement of scalp hair and skin status as well as libido, mood, sleep, and tiredness in postmenopausal women. PMID:22135679

  6. Protective Effects of Soy Oligopeptides in Ultraviolet B-Induced Acute Photodamage of Human Skin.

    Science.gov (United States)

    Zhou, Bing-Rong; Ma, Li-Wen; Liu, Juan; Zhang, Jia-An; Xu, Yang; Wu, Di; Permatasari, Felicia; Luo, Dan

    2016-01-01

    Aim. We explored the effects of soy oligopeptides (SOP) in ultraviolet B- (UVB-) induced acute photodamage of human skin in vivo and foreskin ex vivo. Methods. We irradiated the forearm with 1.5 minimal erythemal dose (MED) of UVB for 3 consecutive days, establishing acute photodamage of skin, and topically applied SOP. Erythema index (EI), melanin index, stratum corneum hydration, and transepidermal water loss were measured by using Multiprobe Adapter 9 device. We irradiated foreskin ex vivo with the same dose of UVB (180 mJ/cm(2)) for 3 consecutive days and topically applied SOP. Sunburn cells were detected by using hematoxylin and eosin staining. Apoptotic cells were detected by using terminal deoxynucleotidyl transferase dUTP nick end labeling assay. Cyclobutane pyrimidine dimers (CPDs), p53 protein, Bax protein, and Bcl-2 protein were detected by using immunohistochemical staining. Results. Compared with UVB group, UVB-irradiated skin with topically applied SOP showed significantly decreased EI. Compared with UVB group, topical SOP significantly increased Bcl-2 protein expression and decreased CPDs-positive cells, sunburn cells, apoptotic cells, p53 protein expression, and Bax protein expressions in the epidermis of UVB-irradiated foreskin. Conclusion. Our study demonstrated that topical SOP can protect human skin against UVB-induced photodamage. PMID:27478534

  7. Effect of Localized Mechanical Indentation on Skin Water Content Evaluated Using OCT

    Directory of Open Access Journals (Sweden)

    Abhijit A. Gurjarpadhye

    2011-01-01

    Full Text Available The highly disordered refractive index distribution in skin causes multiple scattering of incident light and limits optical imaging and therapeutic depth. We hypothesize that localized mechanical compression reduces scattering by expulsing unbound water from the dermal collagen matrix, increasing protein concentration and decreasing the number of index mismatch interfaces between tissue constituents. A swept-source optical coherence tomography (OCT system was used to assess changes in thickness and group refractive index in ex vivo porcine skin, as well as changes in signal intensity profile when imaging in vivo human skin. Compression of ex vivo porcine skin resulted in an effective strain of −58.5%, an increase in refractive index from 1.39 to 1.50, and a decrease in water volume fraction from 0.66 to 0.20. In vivo OCT signal intensity increased by 1.5 dB at a depth of 1 mm, possibly due to transport of water away from the compressed regions. These finding suggest that local compression could be used to enhance light-based diagnostic and therapeutic techniques.

  8. The Glutathione Derivative, GSH Monoethyl Ester, May Effectively Whiten Skin but GSH Does Not

    Directory of Open Access Journals (Sweden)

    Bo Young Chung

    2016-04-01

    Full Text Available Glutathione in its reduced form (GSH is an antioxidant and also is involved in pheomelanin formation. Thus, it has been long believed that GSH has a skin whitening effect. However, its actual or direct effect is unproven. We evaluated the anti-melanogenic effects of GSH and its derivatives in vitro. We examined change of melanogenesis and its related proteins by GSH itself and its derivatives, including GSH monoethyl ester (GSH-MEE, GSH diethyl ester (GSH-DEE and GSH monoisopropyl ester (GSH-MIPE in Melan-A cells, Mel-Ab cells, and B16F10 cells. GSH and GSH-MEE did not display cytotoxic activity, but GSH-MIPE and GSH-DEE did. Intriguingly, GSH itself had no inhibitory effect on melanin production or intracellular tyrosinase activity. Rather, it was GSH-MEE and GSH-MIPE that profoundly reduced the amount of melanin and intracellular tyrosinase activity. Thus, GSH-MEE was selected as a suitable candidate skin-whitening agent and it did not alter melanogenesis-associated proteins such as microphthalmia-associated transcription factor (MITF, tyrosinase, tyrosinase-related protein (TRP-1, and TRP-2, but it did increase the amount of suggested pheomelanin and suggested pheomelanin/eumelanin ratio. GSH-MEE was effective for anti-melanogenesis, whereas GSH itself was not. GSH-MEE could be developed as a safe and efficient agent for the treatment of hyperpigmentation skin disorders.

  9. [Effective and safe pharmacotherapy of acne vulgaris and treatment of sun-damaged skin].

    Science.gov (United States)

    Fendrich, Z; Jandová, E; Finsterlová, M

    2000-03-01

    An inevitable condition for the pharmacist is a basic knowledge of dermatological changes which are prominent in acne and solar impairment of the skin to be able to recommend in a qualified manner an effective and safe treatment to the patient. However, sufferers of the more serious forms of acne should always be referred to their general practitioner, or preferentially a dermatologist. Acne vulgaris is an androgen-induced disorder, but three major mechanisms for the development of the disease have been identified: hypertrophy of the sebaceous gland, hyperkatosis of the follicular epithelium, and proliferation of microbial flora, particularly Propionibacterium acnes. The basis of all lesions is the microcomedone which is developed into the ripe comedone. Inflammatory lesions are thought to be due to proliferation of P. acnes. In the selfmedication of common acne, benzoyl peroxide, which in a 5-10% lotion exerts antimicrobial and keratolytic properties, proved to be useful. Patients appreciate a lot its instant effect which is visible after just one day of treatment. Salicylic acid is another effective drug, which, when used on the long-term basis, has comedolytic properties; it reduces the number of microcomedones and counteracts plugging of the follicles. In addition, in healthy young women who take oral contraception, a triphasic combined oral preparations of contraceptives with newer progestins, notably with norgestimmate, which is practically free of androgenic effects, are recommended with advantage for the treatment of moderate acne vulgaris without any adverse effects. Solar impairment of the skin, the so-called solar ageing, is clinically indistinguishable from biological ageing. Changes connected with solar impairment appear mostly in the dermis, where solar elastosis develops, the skin gets drier and wrinkle formation appears. For the treatment, hydroxy acids are recommended, namely salicylic acid, which is very effective, because in combination with a

  10. Skin photoprotective and antiageing effects of a combination of rosemary (Rosmarinus officinalis) and grapefruit (Citrus paradisi) polyphenols

    Science.gov (United States)

    Nobile, Vincenzo; Michelotti, Angela; Cestone, Enza; Caturla, Nuria; Castillo, Julián; Benavente-García, Obdulio; Pérez-Sánchez, Almudena; Micol, Vicente

    2016-01-01

    Background Plant polyphenols have been found to be effective in preventing ultraviolet radiation (UVR)-induced skin alterations. A dietary approach based of these compounds could be a safe and effective method to provide a continuous adjunctive photoprotection measure. In a previous study, a combination of rosemary (Rosmarinus officinalis) and grapefruit (Citrus paradisi) extracts has exhibited potential photoprotective effects both in skin cell model and in a human pilot trial. Objective We investigated the efficacy of a combination of rosemary (R. officinalis) and grapefruit (C. paradisi) in decreasing the individual susceptibility to UVR exposure (redness and lipoperoxides) and in improving skin wrinkledness and elasticity. Design A randomised, parallel group study was carried out on 90 subjects. Furthermore, a pilot, randomised, crossover study was carried out on five subjects. Female subjects having skin phototype from I to III and showing mild to moderate chrono- or photoageing clinical signs were enrolled in both studies. Skin redness (a* value of CIELab colour space) after UVB exposure to 1 minimal erythemal dose (MED) was assessed in the pilot study, while MED, lipoperoxides (malondialdehyde) skin content, wrinkle depth (image analysis), and skin elasticity (suction and elongation method) were measured in the main study. Results Treated subjects showed a decrease of the UVB- and UVA-induced skin alterations (decreased skin redness and lipoperoxides) and an improvement of skin wrinkledness and elasticity. No differences were found between the 100 and 250 mg extracts doses, indicating a plateau effect starting from 100 mg extracts dose. Some of the positive effects were noted as short as 2 weeks of product consumption. Conclusions The long-term oral intake of Nutroxsun™ can be considered to be a complementary nutrition strategy to avoid the negative effects of sun exposure. The putative mechanism for these effects is most likely to take place through the

  11. Skin photoprotective and antiageing effects of a combination of rosemary (Rosmarinus officinalis and grapefruit (Citrus paradisi polyphenols

    Directory of Open Access Journals (Sweden)

    Vincenzo Nobile

    2016-07-01

    Full Text Available Background: Plant polyphenols have been found to be effective in preventing ultraviolet radiation (UVR-induced skin alterations. A dietary approach based of these compounds could be a safe and effective method to provide a continuous adjunctive photoprotection measure. In a previous study, a combination of rosemary (Rosmarinus officinalis and grapefruit (Citrus paradisi extracts has exhibited potential photoprotective effects both in skin cell model and in a human pilot trial. Objective: We investigated the efficacy of a combination of rosemary (R. officinalis and grapefruit (C. paradisi in decreasing the individual susceptibility to UVR exposure (redness and lipoperoxides and in improving skin wrinkledness and elasticity. Design: A randomised, parallel group study was carried out on 90 subjects. Furthermore, a pilot, randomised, crossover study was carried out on five subjects. Female subjects having skin phototype from I to III and showing mild to moderate chrono- or photoageing clinical signs were enrolled in both studies. Skin redness (a* value of CIELab colour space after UVB exposure to 1 minimal erythemal dose (MED was assessed in the pilot study, while MED, lipoperoxides (malondialdehyde skin content, wrinkle depth (image analysis, and skin elasticity (suction and elongation method were measured in the main study. Results: Treated subjects showed a decrease of the UVB- and UVA-induced skin alterations (decreased skin redness and lipoperoxides and an improvement of skin wrinkledness and elasticity. No differences were found between the 100 and 250 mg extracts doses, indicating a plateau effect starting from 100 mg extracts dose. Some of the positive effects were noted as short as 2 weeks of product consumption. Conclusions: The long-term oral intake of Nutroxsun™ can be considered to be a complementary nutrition strategy to avoid the negative effects of sun exposure. The putative mechanism for these effects is most likely to take place

  12. Effects of single and repeated exposure to biocidal active substances on the barrier function of the skin in vitro

    NARCIS (Netherlands)

    Buist, H.E.; Sandt, J.J.M. van de; Burgsteden, J.A. van; Heer, C. de

    2005-01-01

    The dermal route of exposure is important in worker exposure to biocidal products. Many biocidal active substances which are used on a daily basis may decrease the barrier function of the skin to a larger extent than current risk assessment practice addresses, due to possible skin effects of repeate

  13. Beta Function and Anomalous Dimensions

    DEFF Research Database (Denmark)

    Pica, Claudio; Sannino, Francesco

    2011-01-01

    We demonstrate that it is possible to determine the coefficients of an all-order beta function linear in the anomalous dimensions using as data the two-loop coefficients together with the first one of the anomalous dimensions which are universal. The beta function allows to determine the anomalous...

  14. Anomalous transport equations in toroidal plasmas

    International Nuclear Information System (INIS)

    Reduced transport equations for a toroidal plasma with fluctuations are derived. These equations include the effects of both anomalous and standard neoclassical transport, and allow clarification of the structure of convective fluxes caused by electrostatic and magnetic fluctuations. Special attention is paid to the combined effects of fluctuations and toroidicity on the transport. The formulation retains the effects of a magnetic field inhomogeneity on the anomalous transport. It is shown that phase space diffusion caused by the gradient in the equilibrium magnetic field appears as a pinch flux in the real space

  15. The amelioration effect of tranexamic acid in wrinkles induced by skin dryness.

    Science.gov (United States)

    Hiramoto, Keiichi; Sugiyama, Daijiro; Takahashi, Yumi; Mafune, Eiichi

    2016-05-01

    Tranexamic acid (trans-4-aminomethylcyclohexanecarboxylic acid) is a medical amino acid widely used as an anti-inflammatory and a whitening agent. This study examined the effect of tranexamic acid administration in wrinkle formation following skin dryness. We administered tranexamic acid (750mg/kg/day) orally for 20 consecutive days to Naruto Research Institute Otsuka Atrichia (NOA) mice, which naturally develop skin dryness. In these NOA mice, deterioration of transepidermal water loss (TEWL), generation of wrinkles, decrease of collagen type I, and increases in mast cell proliferation and tryptase and matrix metalloproteinase (MMP-1) release were observed. However, these symptoms were improved by tranexamic acid treatment. Moreover, the increase in the β-endorphin level in the blood and the expression of μ-opioid receptor on the surface of fibroblasts increased by tranexamic acid treatment. In addition, when the fibroblasts induced by tranexamic acid treatment were removed, the amelioration effect by tranexamic acid treatment was halved. On the other hand, tranexamic acid treated NOA mice and mast cell removal in tranexamic acid treated NOA mice did not result in changes in the wrinkle amelioration effect. Additionally, the amelioration effect of mast cell deficient NOA mice was half that of tranexamic acid treated NOA mice. These results indicate that tranexamic acid decreased the proliferation of mast cells and increases the proliferation of fibroblasts, subsequently improving wrinkles caused by skin dryness. PMID:27133035

  16. Effects of Orally Administered Pyrroloquinoline Quinone Disodium Salt on Dry Skin Conditions in Mice and Healthy Female Subjects.

    Science.gov (United States)

    Nakano, Masahiko; Kamimura, Ayako; Watanabe, Fumiko; Kamiya, Toshikazu; Watanabe, Daisuke; Yamamoto, Etsushi; Fukagawa, Mitsuhiko; Hasumi, Keiji; Suzuki, Eriko

    2015-01-01

    Pyrroloquinoline quinone (PQQ) is a coenzyme involved in the redox-cycling system. The supplemental use of PQQ has been examined based on its properties as an antioxidant and redox modulator. Although an animal study on deficiency of PQQ suggested that PQQ contributes to skin conditions, its efficacy in humans has not been reported. The present study aimed to investigate the effects of orally administered PQQ on skin moisture, viscoelasticity, and transepidermal water loss (TEWL) both in dry skin mouse models and in healthy female subjects with a subjective symptom of dry skin. In our dry skin mouse model study, oral intake of PQQ (0.0089%, w/w, in the diet for 6 wk) significantly decreased the number of mast cells in the dermis and the number of CD3⁺ T-cells in the epidermis. In our human study, oral intake of PQQ (20 mg/d for 8 wk) significantly inhibited the increase in TEWL on the forearm. Finally, subject questionnaires showed positive impressions for the improvement of skin conditions. These results suggest that oral intake of PQQ improves skin conditions both in female subjects with dry skin and in mice with a compromised skin barrier function. PMID:26226961

  17. Effect of skin contact and pressure on the composition of Sauvignon Blanc must.

    Science.gov (United States)

    Maggu, Manu; Winz, Robert; Kilmartin, Paul A; Trought, Michael C T; Nicolau, Laura

    2007-12-12

    Early white winemaking operations are known to affect the extraction of grape skin compounds into the juice fraction, which will dictate their concentration in the resulting wine. Grape skin contact and the amount of pressure applied during grape pressing affect the extraction of varietal aromas located in the skins. Compounds such as the polyphenols and glutathione, with antioxidant properties involved in juice oxidation processes and white wine stability, are also affected. The present study evaluates how grape skin contact and the amount of pressure applied during grape pressing affect the levels of S-(3-hexan-l-ol)cysteine (3MH-S-cys, a key grape-derived precursor to the volatile thiol 3-mercapto-hexanol (3MH), which is reminiscent of passion fruit aroma); 2-methoxy-3-isobutylpyrazine (IBMP, with a capsicum-like descriptor); phenolic compounds; and glutathione in Sauvignon Blanc juice. The study was conducted using grapes obtained from commercial Marlborough (New Zealand) vineyards, using both commercial and laboratory grape-processing procedures. Immobilized metal ion chromatography was used to isolate the 3MH- S-cys precursor from the juices. The isolated precursor was then volatilized by trimethylsilylation and analyzed using gas chromatography/mass spectrometry (GC/MS). IBMP was analyzed by GC/MS after solvent extraction, and a high-performance liquid chromatography method was used for the quantification of phenolic compounds and glutathione. 3MH- S-cys levels were seen to increase in juice fractions obtained from a winery press operating at higher pressures. The increase was attributed to the cumulative effect of longer skin contact time and the amount of pressure applied. The highly water-soluble IBMP was less affected by the amount of pressure applied during commercial grape pressing. Additional information was generated by the specific assessment of skin contact and applied pressure during grape pressing in a laboratory trial. In this trial, a long (32

  18. Evaluation of the effect of formalin fixation on skin specimens in dogs and cats

    Directory of Open Access Journals (Sweden)

    Jaimie L. Miller

    2014-03-01

    Full Text Available Skin and subcutaneous tissues are the origin of most common neoplasms affecting dogs, accounting for approximately one third of all tumors encountered in the species. Surgical excision is frequently the best chance for a cure; determining factors influencing the success of excision are vital for surgical management of cases. This work examined the shrinkage of skin of various lengths from three sites in formalin for both dogs and cats. Tissues were measured on the animal (initial measurement, at the time of excision (post-removal, and after formalin fixation (post-fixation. While shrinkage after tissue removal was found in samples from the thorax, abdomen, and rear leg in dogs and from the rear leg in cats, no significant shrinkage due to formalin fixation was detected in any sample except for the thoracic samples from the dog. Therefore, when determining where to make incisions to effect a surgical cure, initial measurements should take into account tissue shrinkage effects.

  19. Food Matrix Effects of Polyphenol Bioaccessibility from Almond Skin during Simulated Human Digestion

    Science.gov (United States)

    Mandalari, Giuseppina; Vardakou, Maria; Faulks, Richard; Bisignano, Carlo; Martorana, Maria; Smeriglio, Antonella; Trombetta, Domenico

    2016-01-01

    The goal of the present study was to quantify the rate and extent of polyphenols released in the gastrointestinal tract (GIT) from natural (NS) and blanched (BS) almond skins. A dynamic gastric model of digestion which provides a realistic simulation of the human stomach was used. In order to establish the effect of a food matrix on polyphenols bioaccessibility, NS and BS were either digested in water (WT) or incorporated into home-made biscuits (HB), crisp-bread (CB) and full-fat milk (FM). Phenolic acids were the most bioaccessible class (68.5% release from NS and 64.7% from BS). WT increased the release of flavan-3-ols (p antioxidant status in the digestion medium, indicating that phenolic compounds could bind protein present in the food matrix. The release of bioactives from almond skins could explain the beneficial effects associated with almond consumption. PMID:27649239

  20. Effect of nisin and doxorubicin on DMBA-induced skin carcinogenesis--a possible adjunct therapy.

    Science.gov (United States)

    Preet, Simran; Bharati, Sanjay; Panjeta, Anshul; Tewari, Rupinder; Rishi, Praveen

    2015-11-01

    In view of the emergence of multidrug-resistant cancer cells, there is a need for therapeutic alternatives. Keeping this in mind, the present study was aimed at evaluating the synergism between nisin (an antimicrobial peptide) and doxorubicin (DOX) against DMBA-induced skin carcinogenesis. The possible tumoricidal activity of the combination was evaluated in terms of animal bioassay observations, changes in hisotological architecture of skin tissues, in situ apoptosis assay (TUNEL assay) and in terms of oxidant and antioxidant status of the skin tissues. In vivo additive effect of the combination was evidenced by larger decreases in mean tumour burden and tumour volume in mice treated with the combination than those treated with the drugs alone. Histological observations indicated that nisin-DOX therapy causes chromatin condensation and marginalisation of nuclear material in skin tissues of treated mice which correlated well with the results of TUNEL assay wherein a marked increase in the rate of apoptosis was revealed in tissues treated with the combination. A slightly increased oxidative stress in response to the adjunct therapy as compared to dox-alone-treated group was revealed by levels of lipid peroxidation (LPO) and nitrite generation in skin tissue-treated mice. An almost similar marginal enhancement in superoxide dismutase levels corresponding with a decrease in catalase activity could also be observed in nisin + DOX-treated groups as compared to nisin and dox-alone-treated groups. These results point towards the possible use of nisin as an adjunct to doxorubicin may help in developing alternate strategies to combat currently developing drug resistance in cancer cells.

  1. The effect of ginkgo biloba extract on radiosensitivity of mouse skin and jejunal crypt

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Kyung Hwan; Ha, Sung Whan [Seoul National Univ. Medical College, Seoul (Korea, Republic of)

    1998-06-01

    Ginkgo biloba extract(GBE) is known to increase the peripheral blood circulation. This study was designed to evaluate the effect of GBE on the acute normal tissue radiation reaction. C3H mice were divided into two groups, radiation alone and two doses GBE plus radiation, for both acute skin reaction and jejunal crypt assay. GBE was given i.p. one hour before irradiation with priming dose given one day earlier. Thirty to Fifty Gy for acute skin reaction and 11 to 14 Gy for jejunal crypt were irradiated to right hind leg and whole body, respectively. Radiation doses(RD{sub 50}) for peak skin score of 2.0 were 44.2Gy(40.6-48.2Gy) for radiation alone and 44.4Gy(41.6-47.4Gy) for two doses GBE plus radiation, showing no effect of GBE on acute radiation skin damage. The numbers of regenerating jejunal crypts per circumference were also almost the same for each radiation dose level(p=0.57-0.94), and the mean lethal doses(D{sub o}) were 1.80Gy(1.57-2.09Gy) for radiation alone and 1.88Gy(1.65-2.18Gy) for two doses GBE plus radiation, indicating no effect of GBE on jejunal crypt cell survival after radiation. GBE doesn't increase acute normal tissue radiation reaction in this model system. As GBE was verified to enhance radiation effect on tumor, high therapeutic gain is expected when GBE is combined with radiation therapy.

  2. The Effects of Mucopolysaccharide Polysulphate on Hydration and Elasticity of Human Skin

    OpenAIRE

    Rungsima Wanitphakdeedecha; Sasima Eimpunth; Woraphong Manuskiatti

    2011-01-01

    Background. Mucopolysaccharide polysulphate (MPS) has been used in medicine as an anti-inflammatory and antithrombotic agent for over 50 years. Its chemical structure permits considerable hydrogen bonding with adjacent water molecules, which effectively leads to hydration of the surrounding tissue. In addition, it stimulates endogenous hyaluronate synthesis, resulting in an increase in water-binding capacity and viscoelasticity of the skin. Objective. To study the efficacy of 0.1% MPS on hydr...

  3. Studies on the Effects of Deltamethrin on Sodium Net Transport Through the in vivo Amphibian Skin

    Institute of Scientific and Technical Information of China (English)

    ALFREDOSALIBIAN; JOSEL.MARAZZO

    1995-01-01

    The action of micromolar concentrations of Deltamethrin on sodium net transport through the in vivo skin of the South American toad Bufo arenarum was studied.The effect or pure ethanolic insecticide solutions and commercial formulations when applied on the mucosal surface was assayed.Deltamethrin provoked a concentration-independent inhibition;the highest inhibition was found at the lowest concentrations.At highest concentrations of the insecticide the Jn Na was not altered.

  4. Protective effect of selenium and zinc on UV-A damage in human skin fibroblasts

    International Nuclear Information System (INIS)

    Ultraviolet A radiation participates in cytotoxicity and carcinogensis of the skin by a mechanism involving the generation of reactive oxygen species. Endogenous antiradical defense systems utilize metalloenzymes including Se-dependent glutathione peroxidase and Cu and Zn superoxide dismutase. The aim of the present work was to determine the protective effect of two trace elements, Se and Zn, on cultured human diploid fibroblasts exposed to UV-A radiation (broad-spectrum source with a maximum intensity at 375 nm). (Author)

  5. The effect of ginkgo biloba extract on radiosensitivity of mouse skin and jejunal crypt

    International Nuclear Information System (INIS)

    Ginkgo biloba extract(GBE) is known to increase the peripheral blood circulation. This study was designed to evaluate the effect of GBE on the acute normal tissue radiation reaction. C3H mice were divided into two groups, radiation alone and two doses GBE plus radiation, for both acute skin reaction and jejunal crypt assay. GBE was given i.p. one hour before irradiation with priming dose given one day earlier. Thirty to Fifty Gy for acute skin reaction and 11 to 14 Gy for jejunal crypt were irradiated to right hind leg and whole body, respectively. Radiation doses(RD50) for peak skin score of 2.0 were 44.2Gy(40.6-48.2Gy) for radiation alone and 44.4Gy(41.6-47.4Gy) for two doses GBE plus radiation, showing no effect of GBE on acute radiation skin damage. The numbers of regenerating jejunal crypts per circumference were also almost the same for each radiation dose level(p=0.57-0.94), and the mean lethal doses(Do) were 1.80Gy(1.57-2.09Gy) for radiation alone and 1.88Gy(1.65-2.18Gy) for two doses GBE plus radiation, indicating no effect of GBE on jejunal crypt cell survival after radiation. GBE doesn't increase acute normal tissue radiation reaction in this model system. As GBE was verified to enhance radiation effect on tumor, high therapeutic gain is expected when GBE is combined with radiation therapy

  6. Effect of Microalgal Extracts of Tetraselmis suecica against UVB-Induced Photoaging in Human Skin Fibroblasts

    OpenAIRE

    Jo, Wol Soon; Yang, Kwang Mo; Park, Hee Sung; Kim, Gi Yong; Nam, Byung Hyouk; Jeong, Min Ho; Choi, Yoo Jin

    2012-01-01

    Exposure of cells to ultraviolet B (UVB) radiation can induce production of free radicals and reactive oxygen species (ROS), which damage cellular components. In addition, these agents can stimulate the expression of matrix metalloproteinase (MMP) and decrease collagen synthesis in human skin cells. In this study, we examined the anti-photoaging effects of extracts of Tetraselmis suecica (W-TS). W-TS showed the strongest scavenging activity against 2,2-difenyl-1-picrylhydrazyl (DPPH) and pero...

  7. Protective effect of transparent film dressing on proton therapy induced skin reactions

    Directory of Open Access Journals (Sweden)

    Whaley Jonathan T

    2013-01-01

    Full Text Available Abstract Objective Proton therapy can result in clinically significant radiation dermatitis. In some clinical scenarios, such as lung or breast cancer, the risk of severe radiation dermatitis may limit beam arrangement and prescription doses. Patients undergoing proton therapy for prostate cancer commonly develop mild radiation dermatitis. Herein, we report the outcomes of two prostate cancer patients whose radiation dermatitis appears to have been substantially diminished by transparent film dressings (Beekley stickers. Methods This is a descriptive report of the skin toxicity observed in two patients undergoing proton therapy for prostate cancer at a single institution in 2011. A phantom dosimetric study was performed to evaluate the impact of a transparent film dressing on a beam’s spread out Bragg peak (SOBP. Results Two patients with low risk prostate cancer were treated with proton therapy to a total dose of 79.2Gy (RBE in 1.8 Gy (RBE fractions using two opposed lateral beams daily. Both patients had small circular (2.5 cm diameter transparent adhesive markers placed on their skin to assist with daily alignment. Patient 1 had markers in place bilaterally for the entirety of treatment. Patient 2 had a marker in place for three weeks on one side and six weeks on the other. Over the course of therapy, both men developed typical Grade 1 radiation dermatitis (asymptomatic erythema on their hips; however, in both patients, the erythema was substantially decreased beneath the markers. Patient 2 demonstrated less attenuation and thus greater erythema in the skin covered for three weeks compared to the skin covered for six weeks. The difference in skin changes between the covered and uncovered skin persisted for at least 1 month. A phantom study of double scattered beam SOBP with and without the marker in the beam path showed no gross dosimetric effect. Conclusions Transparent adhesive markers appear to have attenuated radiation dermatitis in

  8. Protective effect of transparent film dressing on proton therapy induced skin reactions

    International Nuclear Information System (INIS)

    Proton therapy can result in clinically significant radiation dermatitis. In some clinical scenarios, such as lung or breast cancer, the risk of severe radiation dermatitis may limit beam arrangement and prescription doses. Patients undergoing proton therapy for prostate cancer commonly develop mild radiation dermatitis. Herein, we report the outcomes of two prostate cancer patients whose radiation dermatitis appears to have been substantially diminished by transparent film dressings (Beekley stickers). This is a descriptive report of the skin toxicity observed in two patients undergoing proton therapy for prostate cancer at a single institution in 2011. A phantom dosimetric study was performed to evaluate the impact of a transparent film dressing on a beam’s spread out Bragg peak (SOBP). Two patients with low risk prostate cancer were treated with proton therapy to a total dose of 79.2Gy (RBE) in 1.8 Gy (RBE) fractions using two opposed lateral beams daily. Both patients had small circular (2.5 cm diameter) transparent adhesive markers placed on their skin to assist with daily alignment. Patient 1 had markers in place bilaterally for the entirety of treatment. Patient 2 had a marker in place for three weeks on one side and six weeks on the other. Over the course of therapy, both men developed typical Grade 1 radiation dermatitis (asymptomatic erythema) on their hips; however, in both patients, the erythema was substantially decreased beneath the markers. Patient 2 demonstrated less attenuation and thus greater erythema in the skin covered for three weeks compared to the skin covered for six weeks. The difference in skin changes between the covered and uncovered skin persisted for at least 1 month. A phantom study of double scattered beam SOBP with and without the marker in the beam path showed no gross dosimetric effect. Transparent adhesive markers appear to have attenuated radiation dermatitis in these two patients without affecting the SOBP. One patient may

  9. The effect of neutron skin on inclusive prompt photon production in Pb~+~Pb collisions at the LHC

    CERN Document Server

    De, Somnath

    2016-01-01

    Recent experiments on lead (\\textrm{$Pb_{82}^{208}$}) nuclei have observed the celebrated phenomenon of neutron skin-thickness of low energy nuclear physics. The skin-thickness provides a measure of extension of spatial distribution of neutrons inside the atomic nucleus than protons. We have studied the effect of neutron skin-thickness on inclusive prompt photon production in Pb~+~Pb collisions at the Large Hadron Collider energies. We have calculated the \\textquoteleft central-to-peripheral ratio\\textquoteright ($R_\\textrm{cp}$) of prompt photon production with and without accounting for neutron skin effect. The neutron skin causes a characteristic enhancement in the ratio, in particular at forward rapidity, which is distinguishable in our calculation. However a very precise direct photon measurement up to large transverse momenta would be necessary to constrain the feature in experiment.

  10. Effect of balanced low pressure drying of curcuma longa leaf on skin immune activation activities.

    Science.gov (United States)

    Choi, Wooseok; Lim, Hye Won; Lee, Hyeon Yong

    2014-01-01

    The effect of balanced low pressure drying pretreatment associated with ultrasonication extraction (BU) on the enhancement of skin immune modulatory activities of Curcuma longa leaf was studied by comparing with conventional hot air drying (HE), freeze drying (FE) and balanced low pressure drying (BE) pretreatment processes. In considering skin immune activation activities such as the inhibition of hyaluronidase activity, the BU extract showed ca. 10% higher than those of HE, and even higher than that of the FE extract. Nitric oxide production from macrophage of the BU extract in adding 1.0 mg/mL was increased up to 16.5 μM. When measuring inhibition of IL-6 and TNF-a production from the human T lymphocytes (T cell), the BU extract also showed 53% and 78% of inhibition effect, respectively. It is found that the BU extract could effectively suppress the expression levels of skin inflammation related genes such as Cox-2 and iNOS, down to 80% and 85% compared to the control, respectively. Balanced low pressure drying process was especially active on dehydration of the leaves with minimizing the destruction and making easier elution of the bioactive substances, which resulted in higher extraction yield and better biological activities.

  11. Analysis of the Effect of Pile Skin Resistance Verses Pile Diameter Based on Experimental Research

    Directory of Open Access Journals (Sweden)

    S. M. Marandi

    2009-01-01

    Full Text Available In spite of the many recent advances in pile design and execution methods, the quantitative effects of grouted pile skin resistance and form on subsequent pile behavior remains an area for research. There are many parameters involved in the analysis of the bearing capacity of piles and descriptive method theory of the loading effect for each parameter is very complex. Many of these parameters are interrelated and investigation of the relationships leads to complex equations, which cannot be easily solved. The only reliable solution is to study the influence of each parameter by experimental model tests in equipped laboratories. This research presents the results of static compression tests on two model groups of pipe and grouted pile shafts (35mm, 50mm and 60 mm in diameters and 900 mm in length installed into beds of Yazd siliceous sand (located in southeast Iran. The findings of the experimental research were to the average ultimate loads at failure for grouted piles were approximately 12% higher than for the pipe piles. The pile skin resistance is an effective factor on pile bearing capacity, the load transfer response appears to be more plastic with increasing pile diameter in siliceous sand and the skin resistance of the pile was not linearly proportional to the pile diameter and varied with increase in pile diameter.

  12. Effects of High Dose and Long Term Montelukast Treatment on Skin:An Experimental Rat Study

    Directory of Open Access Journals (Sweden)

    Aysel Kükner

    2008-12-01

    Full Text Available Background and Design: The aim of this study was to assess the effects of long term, high dose montelukast administration on normal rat skin by histological examination.Material and Method: Sixteen rats were randomly divided into 2 groups-the control and the montelukast treated (study group (n=8. In the control group 0.2ml of 0.9% NaCl was administered intraperitonealy (i.p. daily for 6 weeks. In the study group the same amount of solution containing 1 mg/kg montelukast was administered i.p. daily for six weeks. At the end of the 6 weeks skin biopsies were taken and histologically examined.Results: There was no significant difference between two groups regarding the dermal and epidermal thickness. Histologic examination of collagen fiber structure did not show difference between two groups. Toluidin blue stained specimens showed that the number of mast cells in dermis significantly decreased in montelukast treated group (p=0.001. Conclusion: Montelukast treatment has significantly decreased the number of mast cells in dermis without any effect on the dermal or epidermal thickness and collagen fiber structure. We think that with the support of further studies, high dose montelukast may have an effective role on the treatment of inflammatory skin disease. (Turkderm 2008; 42: 118-21

  13. Neutron-skin effect and centrality dependence of high-$p_{\\mathrm{T}}$ observables in nuclear collisions

    CERN Document Server

    Helenius, Ilkka; Eskola, Kari J

    2016-01-01

    We report on our studies of the neutron-skin effects in high-$p_{\\mathrm{T}}$ observables at the LHC. We study the impact of the neutron-skin effect on the centrality dependence of inclusive direct photon, high-$p_{\\mathrm{T}}$ hadron and $W^{\\pm}$ production in nuclear collisions at the LHC. The neutron-skin effect refers to the observation that in spherical heavy nuclei, the tail of the neutron distribution extends farther than the distribution of protons, which can affect observables sensitive to electroweak phenomena in very peripheral collisions. We quantify this effect for direct photons, charged hadrons and W bosons as a function of the collision centrality. In the case of direct photons we find that it will be difficult to resolve the neutron-skin effect, given the uncertainties in the nuclear PDFs and their spatial dependence. With charged hadrons and W's, however, up to 20~\\% unambiguous effects are expected for most peripheral collisions.

  14. Temperature dependence of the perpendicular magnetic anisotropy in Ta/Co2FeAl/MgO structures probed by Anomalous Hall Effect

    Science.gov (United States)

    Gabor, M. S.; Petrisor, T.; Pop, O.; Colis, S.; Tiusan, C.

    2015-10-01

    We report a detailed study of the temperature dependence of the magnetic anisotropy in Ta/Co2FeAl/MgO structures by means of Anomalous Hall Effect measurements. The volume magnetic anisotropy, although negligible at room temperature, shows a non-negligible value at low temperatures and favors an in-plane easy magnetization axis. The surface magnetic anisotropy, which promotes the perpendicular magnetic easy axis, shows an increase from 0.76 ± 0.05 erg /cm2 at 300 K, up to 1.08 ± 0.04 erg /cm2 at 5 K, attributed to the evolution of the Co2FeAl layer saturation magnetization with temperature.

  15. The anomalous memory effect related to the relaxation of surface and core moments observed in well-dispersed CoFe2O4 nanoparticles

    Science.gov (United States)

    Huang, S.; Ma, Y. Q.; Xu, S. T.

    2015-12-01

    Well-dispersed uniform cobalt ferrite nanoparticles were synthesized by thermal decomposition of a metal-organic salt in organic solvent with a high boiling point, and characterized by XRD, TEM and detailed magnetic measurements. The moments of CoFe2O4 nanoparticles consist of the core and canted surface moments below 200 K, and the exchange-coupling between the surface and core spins enhanced the remanence (Mr) to saturation (Ms) magnetization ratio (Mr/Ms) at the temperature of 10 K. Interestingly, the anomalous memory effect was observed in a broad temperature range which can be attributed to the relaxation of surface spins below 200 K and the one from the moments of magnetically ordered entity larger than one particle above 200 K.

  16. Origin of the low critical observing temperature of the quantum anomalous Hall effect in V-doped (Bi, Sb)2Te3 film.

    Science.gov (United States)

    Li, W; Claassen, M; Chang, Cui-Zu; Moritz, B; Jia, T; Zhang, C; Rebec, S; Lee, J J; Hashimoto, M; Lu, D-H; Moore, R G; Moodera, J S; Devereaux, T P; Shen, Z-X

    2016-01-01

    The experimental realization of the quantum anomalous Hall (QAH) effect in magnetically-doped (Bi, Sb)2Te3 films stands out as a landmark of modern condensed matter physics. However, ultra-low temperatures down to few tens of mK are needed to reach the quantization of Hall resistance, which is two orders of magnitude lower than the ferromagnetic phase transition temperature of the films. Here, we systematically study the band structure of V-doped (Bi, Sb)2Te3 thin films by angle-resolved photoemission spectroscopy (ARPES) and show unambiguously that the bulk valence band (BVB) maximum lies higher in energy than the surface state Dirac point. Our results demonstrate clear evidence that localization of BVB carriers plays an active role and can account for the temperature discrepancy. PMID:27599406

  17. Ferromagnetism in reactive sputtered Cu0.96Fe 0.04O1-δ nanocrystalline films evidenced by anomalous Hall effect

    KAUST Repository

    Mi, Wenbo

    2011-03-14

    Cu0.96Fe0.04O1-δ nanocrystalline films were fabricated using reactive sputtering at different oxygen partial pressures (PO2). The electrical transport properties of the films were measured in a broad temperature range (10-300 K) under magnetic fields of up to 5T. Anomalous Hall effect (AHE) of up to 0.4μΩ cm was observed at 10 K and decreased to 0.2μΩ cm at 300 K. The characteristic AHE clearly indicated the existence of ferromagnetism in these materials. The AHE weakened as PO2 increased because the increasing PO2 reduced the fraction of Fe2+ ions, and consequently weakened the double exchange coupling between Fe2+-O2--Cu2+ in the materials. © 2011 The Japan Society of Applied Physics.

  18. Effect of Substance P in Staphylococcus aureus and Staphylococcus epidermidis virulence: Implication for skin homeostasis

    Directory of Open Access Journals (Sweden)

    Awa eNdiaye

    2016-04-01

    Full Text Available Staphylococcus aureus and Staphylococcus epidermidis are two major skin associated bacteria, and Substance P (SP is a major skin neuropeptide. Since bacteria are known to sense and response to many human hormones, we investigated the effects of SP on Staphylococci virulence in reconstructed human epidermis model and HaCaT keratinocytes. We show that SP is stimulating the virulence of Staphylococcus aureus and Staphylococcus epidermidis in a reconstructed human epidermis model. qRT-PCR array analysis of 64 genes expressed by keratinocytes in the response to bacterial infection revealed a potential link between the action of SP on Staphylococci and skin physiopathology. qRT-PCR and direct assay of cathelicidin and human β-defensin 2 secretion also provided that demonstration that the action of SP on bacteria is independent of antimicrobial peptide expression by keratinocytes. Considering an effect of SP on S. aureus and S. epidermidis, we observed that SP increases the adhesion potential of both bacteria on keratinocytes. However, SP modulates the virulence of S. aureus and S. epidermidis through different mechanisms. The response of S. aureus is associated with an increase in Staphylococcal Enterotoxin C2 (SEC2 production and a reduction of exolipase processing whereas in S. epidermidis the effect of SP appears mediated by a rise in biofilm formation activity. The Thermo unstable ribosomal Elongation factor Ef-Tu was identified as the SP-interacting protein in S. aureus and S. epidermidis. SP appears as an inter-kingdom communication factor involved in the regulation of bacterial virulence and essential for skin microflora homeostasis.

  19. A new method to evaluate the effects of shear on the skin.

    Science.gov (United States)

    de Wert, Luuk A; Bader, Dan L; Oomens, Cees W J; Schoonhoven, Lisette; Poeze, Martijn; Bouvy, Nicole D

    2015-01-01

    Currently, pressure ulcer preventive strategies focus mainly on pressure redistribution. Little attention is paid to reduce the harmful effects of shear-force, because little is known about pathophysiological aspects of shear-force. Even today, no method to measure the effects of shear-force on the skin is available. Therefore, the aim of this study was to investigate the response to shear-forces in terms of analyzing a noninvasive biomarker and reactive hyperemic parameter measured at the skin of healthy participants. A physical model was developed to produce a combination of pressure and shear or pressure alone on the skin. Ten healthy male participants were included and pressure (3.9 kPa) and a combined loading of pressure and shear (2.4 kPa + 14.5 N) was applied at the volar aspect of the forearms for 15 and 30 minutes. A Sebutape sample was used to collect IL-1α and total protein (TP) noninvasively. The reactive hyperemic parameter was derived from a laser Doppler flowmeter. The increase in IL-1α/TP-ratio after a combined loading of pressure and shear for 30 minutes of 6.2 ± 2.5 was significantly higher compared with all other test conditions (p < 0.05). The increase in cutaneous blood cell flux was already significantly higher when a combined loading of pressure and shear was applied for 15 minutes compared with pressure alone. These results shows that the IL-1α/TP-ratio and cutaneous blood cell flux can be used as robust measures of the effect of shear-force on skin in humans. Therefore, this model can be used to evaluate materials aimed at the reduction of shear.

  20. A new method to evaluate the effects of shear on the skin.

    Science.gov (United States)

    de Wert, Luuk A; Bader, Dan L; Oomens, Cees W J; Schoonhoven, Lisette; Poeze, Martijn; Bouvy, Nicole D

    2015-01-01

    Currently, pressure ulcer preventive strategies focus mainly on pressure redistribution. Little attention is paid to reduce the harmful effects of shear-force, because little is known about pathophysiological aspects of shear-force. Even today, no method to measure the effects of shear-force on the skin is available. Therefore, the aim of this study was to investigate the response to shear-forces in terms of analyzing a noninvasive biomarker and reactive hyperemic parameter measured at the skin of healthy participants. A physical model was developed to produce a combination of pressure and shear or pressure alone on the skin. Ten healthy male participants were included and pressure (3.9 kPa) and a combined loading of pressure and shear (2.4 kPa + 14.5 N) was applied at the volar aspect of the forearms for 15 and 30 minutes. A Sebutape sample was used to collect IL-1α and total protein (TP) noninvasively. The reactive hyperemic parameter was derived from a laser Doppler flowmeter. The increase in IL-1α/TP-ratio after a combined loading of pressure and shear for 30 minutes of 6.2 ± 2.5 was significantly higher compared with all other test conditions (p < 0.05). The increase in cutaneous blood cell flux was already significantly higher when a combined loading of pressure and shear was applied for 15 minutes compared with pressure alone. These results shows that the IL-1α/TP-ratio and cutaneous blood cell flux can be used as robust measures of the effect of shear-force on skin in humans. Therefore, this model can be used to evaluate materials aimed at the reduction of shear. PMID:26426393

  1. Anomalous Hall effect in ZnxFe3-xO4: Universal scaling law and electron localization below the Verwey transition

    Science.gov (United States)

    Jedrecy, N.; Hamieh, M.; Hebert, C.; Escudier, M.; Becerra, L.; Perriere, J.

    2016-08-01

    We show that the well-established universal scaling σxyAHE ˜ σxx1.6 between anomalous Hall and longitudinal conductivities in the low conductivity regime (σxx evolution of the anomalous Hall resistivity suggests the existence of spin polarons whose size would decrease below Tv.

  2. Computed effects of sweat gland ducts on the propagation of 94 GHz waves in skin

    Science.gov (United States)

    Shafirstein, Gal; Moros, Eduardo G.

    2011-03-01

    The effects of sweat gland ducts (SGD) on specific absorption rate and temperatures during millimeter wave irradiation of skin were investigated with a high resolution finite differences time domain model consisting of a 30 μm stratum corneum (SC), a 350 μm epidermis, 1000 μm dermis and five SGD (60 μm radius, 300 μm height, 370 μm separation). The source was a WR-10 waveguide irradiating at 94 GHz. Without SGD, specific absorption rate (SAR) and temperature maximum were in the dermis near epidermis. With SGD, a higher SAR maximum was inside SGD in the epidermis while temperature maximum moved to the epidermis/stratumcorneum junction. SGD significantly affected how GHz waves were absorbed in the skin. Implications of these finding in nociceptive research will be discussed as well as other potential medical applications.

  3. The acute effects of different energy beta-emitters on pig and mouse skin

    International Nuclear Information System (INIS)

    Acute changes were studied in the skin of mice and pigs following irradiation with Sr90 (Esub(max) 2.27 MeV), Tm170 (Esub(max) 0.97 MeV) and Pm147 (Esub(max) 0.225 MeV). Sr90 irradiation in the pig and Sr90 and Tm170 exposure in the mouse resulted in a distinct field-size effect for sources of 5-22.5 mm diameter; ED50 values for moist desquamation were 22.0-27.5 Gy from the 22.5 mm source and 75-90 Gy for the 5 mm source. Tm170 irradiation in the pig produced no distinct area effect for sources of 5-19 mm diameter (ED50 approx.= 80 Gy). Acute tissue breakdown was only achieved in pig and mouse skin by very high doses (ED50 >= 140 Gy) from sources of 147 produced acute epithelial breakdown, only after high skin-surface doses (ED50 550-725 Gy). Area-and energy-related changes can, in part be explained by an hypothesis based on repopulation of the epithelium in the irradiated area by the migration of either cells from the edge of that area and/or cells surviving at the base of hair follicles. Differences in the results in pig and mouse can be explained on the basis of the distribution of target cells in the epidermis at varying depths. (author)

  4. Radioprotective effects of Aloe vera leaf extract on skin of Swiss mice after gamma irradiation

    International Nuclear Information System (INIS)

    Full text: Biological effects of radiation are detrimental to life. Skin being a cell-renewal system is one of the best organ for studying radiation induced effects and their modulation by antioxidants. An attempt has been made to evaluate radioprotective efficacy of Aloe vera leaf extract on skin in Swiss mice (1g/kg body wt/day). The mice selected from inbreed colony were divided into two groups. The first group was given Aloe vera extract orally for 15th consecutive days and served as experimental group while the other group received DDW (vol. equal to Aloe extract) to serve as control group. On the 15th day, after 30 min of above treatment animals of both the groups were exposed to 2 Gy gamma irradiation and autopsied on 6h 1, 3, 7, 14 and 21 days. DNA as well as total protein decreases in control group as compared to the normal value. Surprisingly, in experimental group, DNA and protein increases in comparison to the control group. Thus, Aloe vera were found to have positive influence against radiation induced alterations on skin of Swiss albino mice

  5. Anomalous diffusion of epicentres

    CERN Document Server

    Sotolongo-Costa, Oscar; Posadas, A; Luzon, F

    2007-01-01

    The classification of earthquakes in main shocks and aftershocks by a method recently proposed by M. Baiesi and M. Paczuski allows to the generation of a complex network composed of clusters that group the most correlated events. The spatial distribution of epicentres inside these structures corresponding to the catalogue of earthquakes in the eastern region of Cuba shows anomalous anti-diffusive behaviour evidencing the attractive nature of the main shock and the possible description in terms of fractional kinetics.

  6. Anomalous law of cooling

    OpenAIRE

    Lapas, Luciano C.; Ferreira, Rogelma M. S.; Oliveira, Fernando A.; Rubí, J. Miguel

    2014-01-01

    We analyze the temperature relaxation phenomena of systems in contact with a thermal reservoir that undergo a non-Markovian diffusion process. From a generalized Langevin equation, we show that the temperature is governed by a law of cooling of the Newton's law type in which the relaxation time depends on the velocity autocorrelation and is then characterized by the memory function. The analysis of the temperature decay reveals the existence of an anomalous cooling in which the temperature ma...

  7. Beryllium metal I. experimental results on acute oral toxicity, local skin and eye effects, and genotoxicity.

    Science.gov (United States)

    Strupp, Christian

    2011-01-01

    The toxicity of soluble metal compounds is often different from that of the parent metal. Since no reliable data on acute toxicity, local effects, and mutagenicity of beryllium metal have ever been generated, beryllium metal powder was tested according to the respective Organisation for Economical Co-Operation and Development (OECD) guidelines. Acute oral toxicity of beryllium metal was investigated in rats and local effects on skin and eye in rabbits. Skin-sensitizing properties were investigated in guinea pigs (maximization method). Basic knowledge about systemic bioavailability is important for the design of genotoxicity tests on poorly soluble substances. Therefore, it was necessary to experimentally compare the capacities of beryllium chloride and beryllium metal to form ions under simulated human lung conditions. Solubility of beryllium metal in artificial lung fluid was low, while solubility in artificial lysosomal fluid was moderate. Beryllium chloride dissolution kinetics were largely different, and thus, metal extracts were used in the in vitro genotoxicity tests. Genotoxicity was investigated in vitro in a bacterial reverse mutagenicity assay, a mammalian cell gene mutation assay, a mammalian cell chromosome aberration assay, and an unscheduled DNA synthesis (UDS) assay. In addition, cell transformation was tested in a Syrian hamster embryo cell assay, and potential inhibition of DNA repair was tested by modification of the UDS assay. Beryllium metal was found not to be mutagenic or clastogenic based on the experimental in vitro results. Furthermore, treatment with beryllium metal extracts did not induce DNA repair synthesis, indicative of no DNA-damaging potential of beryllium metal. A cell-transforming potential and a tendency to inhibit DNA repair when the cell is severely damaged by an external stimulus were observed. Beryllium metal was also found not to be a skin or eye irritant, not to be a skin sensitizer, and not to have relevant acute oral

  8. ASSESSMENT OF THE EFFECTIVENESS OF APPLICATION ANTISEPTICS IN PREVENTION OF FOOT SKIN INFLAMMATION

    Directory of Open Access Journals (Sweden)

    Brzeziński Piotr

    2011-01-01

    Full Text Available Introduction: Skin inflammation in the foot soldiers is a major problem, affecting armies around the world. Hence it is important preventive action, to prevent the development of such states. Antiseptic is the destruction of microorganisms present in the tissues by means of antiseptic.Aim: The effectiveness of the use Pigmentum Castelani and Kalium hypermanganicum in the prevention of skin inflammation in the foot soldiers.Material and methods: The study included 30 men middle-aged men 20.5 years and 60 soldiers, as a control group of men with a mean age 21.5 years. The survey was conducted over a period of 3 months. Of the 30 soldiers from the study group in 15 using liquid Pigmentum Castelani - Group I, and in another 15 people a solution of Kalium hypermanganicum - group II. Prophylactic treatment of soldiers received by a certain pattern. The control group was 60 men received no treatment. The observations were performed during clinical examination of foot skin, mycological examination and examination under Wood's lamp.Results: None of the 30 seamen (group I and II test, there was no bacterial or fungal infection of the feet. In the control group were diagnosed 11 cases of athlete's foot feet (64.71% of cases, 3 cases of fungal infection of the back foot (17.65% and 3 cases pitted keratolysis (17.65% of cases.Conclusions: Prophylactic Pigmentum Castelani and Kalium hypermanganicum effectively protects against the development of inflammatory skin feet. This is reflected in the increase in disposal and good health for the soldier.

  9. Chemopreventive effect of Lagenaria siceraria in two stages DMBA plus croton oil induced skin papillomagenesis.

    Science.gov (United States)

    Kumar, Navneet; Kale, Raosaheb K; Tiku, Ashu B

    2013-01-01

    Cancer chemoprevention is a dietary or therapeutic strategy to prevent, suppress, or delay carcinogenesis either at initiation or progression level with nontoxic agents. Use of natural dietary compounds has been a major chemopreventive approach to modulate tumorigenic pathways. In the present study, we have evaluated Lagenaria siceraria (bottle gourd), a common vegetable of Indian household for its chemomodulatory potential. The fruit has been used in traditional medicine for a very long time for health benefits and to cure pain, ulcers, fever, cough, asthma, and other bronchial disorders. However, despite its reported beneficial effect the chemo modulatory potential of this plant has not been reported. Therefore chemopreventive effect of bottle gourd juice (BGJ) was studied against 7,12-dimethylbenz(a)anthracene (DMBA) plus croton oil induced skin papillomagenesis in Swiss albino mice. The effect was studied both at antiinitiation and antiinitiation/promotion level followed by histopathological study. A dose of 2.5% and 5% given in drinking water showed significant decrease in papilloma number, papilloma incidence, papilloma multiplicity, papilloma latency, papilloma volume, and papilloma size in different size range. Histopathological study showed chemopreventive effect by minimizing loss of stratification, a decrease in number of epithelial layers, reducing dermal infiltration and protection for various cytoplasmic changes. Higher dose of BGJ was found to be more effective than lower dose and the chemopreventive effect was maximum for antiinitiation/promotion treatment. Altogether, this study reports the chemopreventive effect of Lagenaria siceraria on skin papillomagenesis for the first time and suggests that its consumption may help in suppression of skin cancer. PMID:23914728

  10. Simulation study of the thermal and the thermoelastic effects induced by pulsed laser absorption in human skin

    Science.gov (United States)

    Kim, Jae-Young; Jang, Kyungmin; Yang, Seung-Jin; Baek, Jun-Hyeok; Park, Jong-Rak; Yeom, Dong-Il; Kim, Ji-Sun; Kim, Hyung-Sik; Jun, Jae-Hoon; Chung, Soon-Cheol

    2016-04-01

    We studied the thermal and the mechanical effects induced by pulsed laser absorption in human skin by numerically solving the heat-transfer and the thermoelastic wave equations. The simulation of the heat-transfer equation yielded the spatiotemporal distribution of the temperature increase in the skin, which was then used in the driving term of the thermoelastic wave equation. We compared our simulation results for the temperature increase and the skin displacements with the measured and numerical results, respectively. For the comparison, we used a recent report by Jun et al. [Sci. Rep. 5, 11016 (2015)], who measured in vivo skin temperature and performed numerical simulation of the thermoelastic wave equation using a simple assumption about the temporal evolution of the temperature distribution, and found their results to be in good agreement with our results. In addition, we obtained solutions for the stresses in the human skin and analyzed their dynamic behaviors in detail.

  11. Anomalous transport in toroidal plasmas

    International Nuclear Information System (INIS)

    When the magnetic moment of particle is conserved, there are three mechanisms which cause anomalous transport. These are: variation of magnetic field strength in flux surface, variation of electrostatic potential in flux surface, and destruction of flux surface. The anomalous transport of different groups of particles resulting from each of these mechanisms is different. This fact can be exploited to determine the cause of transport operative in an experimental situation. This approach can give far more information on the transport than the standard confinement time measurements. To implement this approach, we have developed Monte Carlo codes for toroidal geometries. The equations of motion are developed in a set of non-canonical, practical Boozer co-ordinates by means of Jacobian transformations of the particle drift Hamiltonian equations of motion. Effects of collisions are included by appropriate stochastic changes in the constants of motion. Effects of the loop voltage on particle motions are also included. We plan to apply our method to study two problems: the problem of the hot electron tail observed in edge region of ZT-40, and the energy confinement time in TOKAPOLE II. For the ZT-40 problem three situations will be considered: a single mode in the core, a stochastic region that covers half the minor radius, a stochastic region that covers the entire plasma. A turbulent spectrum of perturbations based on the experimental data of TOKAPOLE II will be developed. This will be used to simulate electron transport resulting from ideal instabilities and resistive instabilities in TOKAPOLE II

  12. Theory of the Muon Anomalous Magnetic Moment

    CERN Document Server

    Melnikov, Kirill

    2006-01-01

    The theory of the muon anomalous magnetic moment is "particle physics in a nutshell" and as such is interesting, exciting and difficult. The current precision of the experimental value for this quantity, improved significantly in the past several years due to experiment E821 at Brookhaven National Laboratory, is so high that a large number of subtle effects not relevant previously, become important for the interpretation of the experimental result. The theory of the muon anomalous magnetic moment is at the cutting edge of current research in particle physics and includes multiloop calculations in both QED and electroweak theory, precision low-energy hadron physics, isospin violations and scattering of light by light. Any deviation between the theoretical prediction and the experimental value might be interpreted as a signal of an as-yet-unknown new physics. This book provides a comprehensive review of the theory of the muon anomalous magnetic moment.

  13. Electroweak Baryogenesis with Anomalous Higgs Couplings

    CERN Document Server

    Kobakhidze, Archil; Yue, Jason

    2015-01-01

    We investigate feasibility of efficient baryogenesis at the electroweak scale within the effective field theory framework based on a non-linear realisation of the electroweak gauge symmetry. In this framework the LHC Higgs boson is described by a singlet scalar field, which, therefore, admits new interactions. Assuming that Higgs couplings with the eletroweak gauge bosons are as in the Standard Model, we demonstrate that the Higgs cubic coupling and the CP-violating Higgs-top quark anomalous couplings alone may drive the a strongly first-order phase transition. The distinguished feature of this transition is that the anomalous Higgs vacuum expectation value is generally non-zero in both phases. We identify a range of anomalous couplings, consistent with current experimental data, where sphaleron rates are sufficiently fast in the 'symmetric' phase and are suppressed in the 'broken' phase and demonstrate that the desired baryon asymmetry can indeed be generated in this framework. This range of the Higgs anomal...

  14. Anomalous magnetohydrodynamics in the extreme relativistic domain

    CERN Document Server

    Giovannini, Massimo

    2016-01-01

    The evolution equations of anomalous magnetohydrodynamics are derived in the extreme relativistic regime and contrasted with the treatment of hydromagnetic nonlinearities pioneered by Lichnerowicz in the absence of anomalous currents. In particular we explore the situation where the conventional vector currents are complemented by the axial-vector currents arising either from the pseudo Nambu-Goldstone bosons of a spontaneously broken symmetry or because of finite fermionic density effects. After expanding the generally covariant equations in inverse powers of the conductivity, the relativistic analog of the magnetic diffusivity equation is derived in the presence of vortical and magnetic currents. While the anomalous contributions are generally suppressed by the diffusivity, they are shown to disappear in the perfectly conducting limit. When the flow is irrotational, boost-invariant and with vanishing four-acceleration the corresponding evolution equations are explicitly integrated so that the various physic...

  15. The effect of alpha-ketoglutarate on a piscine skin model: a molecular and morphological study

    OpenAIRE

    Costa, Rita

    2009-01-01

    Dissertação mest., Ciências Biomédicas, Universidade do Algarve, 2009 Alpha-ketoglutarate (AKG) is a key intermediate in the tricarboxylic acid cycle with important functions in glutamate and glutamine metabolism. Its effect after oral administration was studied in adult sea bream Sparus aurata skin and scales in order to evaluate the effect on collagen synthesis. Scales were removed from one side of the body and allowed to regenerate for 14 days; the control group received unt...

  16. Effects of bosentan on collagen type I synthesis on in vitro culture of scleroderma skin fibroblasts

    Directory of Open Access Journals (Sweden)

    S. Soldano

    2011-01-01

    Full Text Available The present study evaluated the effects of a non-selective endothelin (ETA/B receptors antagonist, on collagen type I (COLI synthesis on in vitro culture of scleroderma (SSc skin fibroblasts (Fb. Fb were obtained from skin biopsies of 6 female SSc patients (mean age 64. 1±6 years, after informed consent and Ethical Committee Approval. Cells were treated with endothelin-I [ET-I, 100nM] for 24 and 48 hrs, pre-treated for I hr with ETA/B receptors antagonist [10nM] alone or followed by ET-I for 24 and 48 hrs. Untreated Fb were used as controls. Immunocytochemistry and western blot analysis were performed to evaluate COLI synthesis. ET-I increased COLI synthesis both at 24 and 48 hrs when compared to controls. ETA/B receptor antagonost blocks the increased COLI synthesis ET-I-mediated both at 24 and 48 hrs vs. ET-I. Results showed that ET-I receptors blockage by ETA/B receptors antagonist might prevent the excessive synthesis of COLI, supporting its positive action in the management of skin fibrosis.

  17. THETA-pinch in an electron-hole plasma under skin effect conditions

    International Nuclear Information System (INIS)

    Equations for theta pinch in semiconductors have been integrated by a computer for the case where the skin thickness is less than the radius of a sample. Under strong skinning solitary waves of density and of magnetic field are produced in a plasma, which move towards the crystal center. The position of the front of the waves and conditions of the maximum plasma compression have been determined. It has been shown that the plasma spatial distribution under theta pinch skinning depends strongly on the shape of the magnetic field pulse and on the ratio of characteristic times (ambipolar diffusion, volume recombination, pulse duration, magnetic field diffusion). In the case where an external magnetic field obeys a harmonic law, the theta pinch has a number of interesting features associated with the capture of the magnetic field by a plasma and with the formation of a neutral layer resulting from the compensation of fields. In such a case at certain stages of the pulse a magnetic field wave arises with a very steep front, which results in an abrupt increase in the concentrational effect. The results of the theory developed have been compared with experimental data

  18. Meta-analysis of the effectiveness of surgical scalpel or diathermy in making abdominal skin incisions.

    LENUS (Irish Health Repository)

    Ahmad, Nasir Zaheer

    2012-02-01

    BACKGROUND: Surgical scalpels are traditionally used to make skin incisions. Diathermy incisions on contrary are less popular among the surgeons. The aim of this meta-analysis was to compare the effectiveness of both techniques and address the common fallacies about diathermy incisions. METHODS: A literature search of MEDLINE and Cochrane databases was done, using the keywords diathermy, cold scalpel, and incisions. Eleven clinical trials comparing both methods of making skin incisions were selected for meta-analysis. The end points compared included postoperative wound infection, pain in first 24 hours after surgery, time taken to complete the incisions, and incision-related blood loss. RESULTS: Postoperative wound infection rate was comparable in both techniques (P = 0.147, odds ratio = 1.257 and 95% CI = 0.923-1.711). Postoperative pain was significantly less with diathermy incisions in first 24 hours (P = 0.031, weighted mean difference = 0.852 and 95% CI = 0.076-1.628). Similarly, the time taken to complete the incision and incision-related blood loss was significantly less with diathermy incisions (95% CI = 0.245-0.502 and 0.548-1.020, respectively). CONCLUSION: Diathermy incisions are equally prone to get wound infection, as do the incisions made with scalpel. Furthermore, lower incidence of early postoperative pain, swiftness of the technique, and a reduced blood loss are the encouraging facts supporting routine use of diathermy for abdominal skin incisions after taking careful precautions.

  19. Clinical, histopathological and immunological effects of exposure of canine skin to Malassezia pachydermatis.

    Science.gov (United States)

    Bond, R; Patterson-Kane, J C; Lloyd, D H

    2004-04-01

    The effects of the daily application for 7 days of suspensions of Malassezia pachydermatis to normal canine skin were evaluated in 10 beagle dogs. Four out of six dogs challenged without occlusion developed transient lesions generally characterized clinically by mild erythema with papules and histologically by mild epidermal hyperplasia and a superficial perivascular dermatitis. Saline-treated control sites showed no clinical signs. In four dogs challenged with occlusion, skin lesions occurred at both yeast and saline-treated sites; erythema and papules were more severe at the yeast-treated sites in three dogs. Occlusion induced more persistent lesions, which resolved within 24 days. Population densities of the yeast were highest at day 8 and declined rapidly following cessation of application. Peripheral blood mononuclear cell proliferation indices following M. pachydermatis exposure in vitro and serum concentrations of M. pachydermatis-specific IgG antibodies did not vary significantly during the study. Delayed (24 h) intradermal test reactivity to M. pachydermatis antigens developed in all eight dogs with clinical signs following yeast exposure. This study suggests that the resistance of healthy canine skin to infection by M. pachydermatis is mediated by local delayed hypersensitivity responses and, or innate epidermal immune mechanisms. PMID:15124870

  20. Synergistic effects of ethosomes and chemical enhancers on enhancement of naloxone permeation through human skin.

    Science.gov (United States)

    Xu, D H; Zhang, Q; Feng, X; Xu, X; Liang, W Q

    2007-04-01

    The purpose of this study was to investigate the effects of ethosomes, chemical enhancers and their binary combination on the in vitro permeability enhancement of naloxone through human skin. Franz diffusion cells were used for the percutaneous absorption studies. Propylene glycol (PG), N,N-dimethyl formamide (N,N-DMF), N,N-dimethyl acetamide (N,N-DMA), dimethyl sulfoxide (DMSO), Azone and polyethylene glycol 400 (PEG400), were chosen as the chemical enhancers. Naloxone ethosomes showed 11.68 times increase in steady-state flux compared to phosphate buffered solution (PBS). Ethosomes in combination with chemical enhancers synergistically increased (p ethosomal form dramatically enhanced the skin permeation of naloxone in vitro compared with ethosomes (steady-state flux: 96.75 +/- 5.70 microg x cm(-2) x h(-1) vs 20.56 +/- 1.67 microg x cm(-2) x h(-1)). Ethosomal carrier and enhancers accumulated in the skin after 24 h were greater than that of PBS.

  1. Protective Effects of B Vitamins and Antioxidants on the Risk of Arsenic-Related Skin Lesions in Bangladesh

    OpenAIRE

    Lydia B Zablotska; Chen, Yu; Graziano, Joseph H.; Parvez, Faruque; van Geen, Alexander; Howe, Geoffrey R.; Ahsan, Habibul

    2008-01-01

    Background An estimated 25–40 million of the 127 million people of Bangladesh have been exposed to high levels of naturally occurring arsenic from drinking groundwater. The mitigating effects of diet on arsenic-related premalignant skin lesions are largely unknown. Objectives The purpose of this study was to clarify the effects of the vitamin B group (thiamin, riboflavin, niacin, pyridoxine, and cobalamin) and antioxidants (vitamins A, C, and E) on arsenic-related skin lesions. Methods We per...

  2. Clinical Evidence of Effects of Lactobacillus plantarum HY7714 on Skin Aging: A Randomized, Double Blind, Placebo-Controlled Study.

    Science.gov (United States)

    Lee, Dong Eun; Huh, Chul-Sung; Ra, Jehyeon; Choi, Il-Dong; Jeong, Ji-Woong; Kim, Sung-Hwan; Ryu, Ja Hyun; Seo, Young Kyoung; Koh, Jae Sook; Lee, Jung-Hee; Sim, Jae-Hun; Ahn, Young-Tae

    2015-12-28

    The beneficial effects of probiotics are now widely reported, although there are only a few studies on their anti-aging effects. We have found that Lactobacillus plantarum HY7714 (HY7714) improves skin hydration and has anti-photoaging effects, and in the present study, we have further evaluated the anti-aging effect of HY7714 via a randomized, double blind, placebo-controlled clinical trial. The trial included 110 volunteers aged 41 and 59 years who have dry skin and wrinkles. Participants took 1 × 10(10) CFU/day of HY7714 (probiotic group) or a placebo (placebo group) for 12 weeks. Skin hydration, wrinkles, skin gloss, and skin elasticity were measured every 4 weeks during the study period. There were significant increases in the skin water content in the face (p < 0.01) and hands (p < 0.05) at week 12 in the probiotic group. Transepidermal water loss decreased significantly in both groups at weeks 4, 8, and 12 (p < 0.001 compared with baseline), and was suppressed to a greater extent in the face and forearm in the probiotic group at week 12. Volunteers in the probiotic group had a significant reduction in wrinkle depth at week 12, and skin gloss was also significantly improved by week 12. Finally, skin elasticity in the probiotic group improved by 13.17% (p < 0.05 vs. controls) after 4 weeks and by 21.73% (p < 0.01 vs. controls) after 12 weeks. These findings are preliminary confirmation of the anti-aging benefit to the skin of L. plantarum HY7714 as a nutricosmetic agent.

  3. Effects of laser therapy on chronic skin ulcers healing interventions for Sudanese patients

    Directory of Open Access Journals (Sweden)

    Abdelrazig M. Abdelbagi

    2015-12-01

    Results: Utilization of laser dosage (energy density of 40 J/cm2 and 1.6 w/cm2 power density of the wavelength 820 nm and 30 J/cm2 energy density and power density of 0.24 w/cm2 of 780 nm wavelength, in addition to energy density of 8 J/cm2 and power density of 0.24 w/cm2 and 0.40 w/cm2 and energy density of 1.6 J/cm2 for the 675 wavelength was applied. In this study, we used the bio-stimulation effect of LLLT to enhance healing through immune modulation. However, the application of low level diode laser in the treatment of diabetic wounds can be accompanied by low energy density and short wavelength to give better results in a short time and a good diagnostic accuracy for its potentiality in the field. Conclusions: Consequently, the brown skins in Sub-Saharan region for different tissues of Sudanese diabetic patients of chronic skin ulcer can be treated with different wavelengths and energy relative to tissues softening and laser parameters of that optimum values were obtained. The assessment of skin regeneration using laser therapy expose that the quality of growth, the reasonable period of healing and decreases the risk skin infection were achieved. The process of diabetic wounds curing and de-pigmentation, potential resident of decreasing pain and an efficient adjunct to a standard wound management was obtained. [Int J Res Med Sci 2015; 3(12.000: 3720-3725

  4. General considerations of the choice of dose limits, averaging areas and weighting factors for the skin in the light of revised skin cancer risk figures and experimental data on non-stochastic effects

    International Nuclear Information System (INIS)

    Recent biological data from man and pig on the non-stochastic effects following exposure with a range of β-emitters are combined with recent epidemiological analyses of skin cancer risks in man to form a basis for suggested improved protection criteria following whole- or partial-body skin exposures. Specific consideration is given to the choice of an organ weighting factor for evaluation of effective dose-equivalent. Since stochastic and non-stochastic end-points involve different cell types at different depths in the skin, the design of an ideal physical dosemeter may depend on the proportion of the body skin exposed and the radiation penetrating power. Possible choices of design parameters for skin dosemeters are discussed. Limitation of skin exposure from small radioactive sources ('hot particles') is addressed using animal data. (author)

  5. Integrated Experimental and Computational Approach to Understand the Effects of Heavy Ion Radiation on Skin Homeostasis.

    Energy Technology Data Exchange (ETDEWEB)

    von Neubeck, Claere; Shankaran, Harish; Geniza, Matthew; Kauer, Paula M.; Robinson, Robert J.; Chrisler, William B.; Sowa, Marianne B.

    2013-08-08

    The effects of low dose high linear energy transfer (LET) radiation on human health are of concern for both space and clinical exposures. As epidemiological data for such radiation exposures are scarce for making relevant predictions, we need to understand the mechanism of response especially in normal tissues. Our objective here is to understand the effects of heavy ion radiation on tissue homeostasis in a realistic model system. Towards this end, we exposed an in vitro three dimensional skin equivalent to low fluences of Neon (Ne) ions (300 MeV/u), and determined the differentiation profile as a function of time following exposure using immunohistochemistry. We found that Ne ion exposures resulted in transient increases in the tissue regions expressing the differentiation markers keratin 10, and filaggrin, and more subtle time-dependent effects on the number of basal cells in the epidermis. We analyzed the data using a mathematical model of the skin equivalent, to quantify the effect of radiation on cell proliferation and differentiation. The agent-based mathematical model for the epidermal layer treats the epidermis as a collection of heterogeneous cell types with different proliferation/differentiation properties. We obtained model parameters from the literature where available, and calibrated the unknown parameters to match the observed properties in unirradiated skin. We then used the model to rigorously examine alternate hypotheses regarding the effects of high LET radiation on the tissue. Our analysis indicates that Ne ion exposures induce rapid, but transient, changes in cell division, differentiation and proliferation. We have validated the modeling results by histology and quantitative reverse transcription polymerase chain reaction (qRT-PCR). The integrated approach presented here can be used as a general framework to understand the responses of multicellular systems, and can be adapted to other epithelial tissues.

  6. Effect of Alpinia zerumbet components on antioxidant and skin diseases-related enzymes

    Directory of Open Access Journals (Sweden)

    Chompoo Jamnian

    2012-07-01

    Full Text Available Abstract Background The skin is chronically exposed to endogenous and environmental pro-oxidant agents, leading to the harmful generation of reactive oxygen species. Antioxidant is vital substances which possess the ability to protect the body from damage cause by free radicals induce oxidative stress. Alpinia zerumbet, a traditionally important economic plant in Okinawa, contains several interesting bioactive constituents and possesses health promoting properties. In this regard, we carried out to test the inhibitory effect of crude extracts and isolated compounds from A. zerumbet on antioxidant and skin diseases-related enzymes. Methods The antioxidant activities were examined by DPPH, ABTS and PMS-NADH radical scavenging. Collagenase, elastase, hyaluronidase and tyrosinase were designed for enzymatic activities to investigate the inhibitory properties of test samples using a continuous spectrophotometric assay. The inhibitory capacity of test samples was presented at half maximal inhibitory concentration (IC50. Results The results showed that aqueous extract of the rhizome was found to have greater inhibitory effects than the others on both of antioxidant and skin diseases-related enzymes. Furthermore, 5,6-dehydrokawain (DK, dihydro-5,6-dehydrokawain (DDK and 8(17,12-labdadiene-15,16-dial (labdadiene, isolated from rhizome, were tested for antioxidant and enzyme inhibitions. We found that DK showed higher inhibitory activities on DPPH, ABTS and PMS-NADH scavenging (IC50 = 122.14 ± 1.40, 110.08 ± 3.34 and 127.78 ± 4.75 μg/ml, respectively. It also had stronger inhibitory activities against collagenase, elastase, hyaluronidase and tyrosinase (IC50 = 24.93 ± 0.97, 19.41 ± 0.61, 19.48 ± 0.24 and 76.67 ± 0.50 μg/ml, respectively than DDK and labdadiene. Conclusion Our results indicate that the rhizome aqueous extract proved to be the source of bioactive compounds against enzymes responsible for

  7. Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects.

    Science.gov (United States)

    Knott, Anja; Achterberg, Volker; Smuda, Christoph; Mielke, Heiko; Sperling, Gabi; Dunckelmann, Katja; Vogelsang, Alexandra; Krüger, Andrea; Schwengler, Helge; Behtash, Mojgan; Kristof, Sonja; Diekmann, Heike; Eisenberg, Tanya; Berroth, Andreas; Hildebrand, Janosch; Siegner, Ralf; Winnefeld, Marc; Teuber, Frank; Fey, Sven; Möbius, Janne; Retzer, Dana; Burkhardt, Thorsten; Lüttke, Juliane; Blatt, Thomas

    2015-01-01

    Ubiquinone (coenzyme Q10, Q10) represents an endogenously synthesized lipid-soluble antioxidant which is crucial for cellular energy production but is diminished with age and under the influence of external stress factors in human skin. Here, it is shown that topical Q10 treatment is beneficial with regard to effective Q10 replenishment, augmentation of cellular energy metabolism, and antioxidant effects. Application of Q10-containing formulas significantly increased the levels of this quinone on the skin surface. In the deeper layers of the epidermis the ubiquinone level was significantly augmented indicating effective supplementation. Concurrent elevation of ubiquinol levels suggested metabolic transformation of ubiquinone resulting from increased energy metabolism. Incubation of cultured human keratinocytes with Q10 concentrations equivalent to treated skin showed a significant augmentation of energy metabolism. Moreover, the results demonstrated that stressed skin benefits from the topical Q10 treatment by reduction of free radicals and an increase in antioxidant capacity.

  8. Combined effects of treatment with vitamin C, vitamin E and selenium on the skin of diabetic rats.

    Science.gov (United States)

    Sokmen, B B; Basaraner, H; Yanardag, R

    2013-04-01

    The aim of this study was to investigate the effects of vitamin C, vitamin E and selenium (Se) on the skin tissue of streptozotocin-induced diabetic rats. Swiss albino rats were divided into four groups: control, control + antioxidants, diabetic, diabetic + antioxidants groups. Diabetes was induced by intraperitoneal injection of 65 mg/kg streptozotocin. Vitamin C (250 mg/kg), vitamin E (250 mg/kg) and Se (0.2 mg/kg) were given by gavage technique to rats of one diabetic and one control group for 30 days. In the diabetic group, the levels of serum urea and creatinine, skin lipid peroxidation and nonenzymatic glycosylation levels increased, but skin glutathione levels decreased. Treatment with vitamin C, vitamin E and Se reversed these effects. The present study showed that vitamin C, vitamin E and Se exerted antioxidant effects and consequently may prevent skin damage caused by streptozotocin-induced diabetes.

  9. Differential effects of topically applied formalin and aromatic compounds on neurogenic-mediated microvascular leakage in rat skin.

    Science.gov (United States)

    Futamura, Masaki; Goto, Shiho; Kimura, Ryoko; Kimoto, Izumi; Miyake, Mio; Ito, Komei; Sakamoto, Tatsuo

    2009-01-01

    Various volatile organic compounds (VOCs) act as a causative agent of skin inflammation. We investigated the effect of topical application of several VOCs and formalin on microvascular leakage in rat skin. We tested capsaicin, which is a reagent that specifically causes the skin response via endogenously released tachykinins. Evans blue dye extravasation served as an index of the increase in skin vascular permeability. After shaving the abdomen, we applied formalin, m-xylene, toluene, styrene, benzene, ethylbenzene, acetone, diethyl ether, hexane, heptane, cyclohexane and capsaicin to the skin. At 40min after application, skin samples were collected. Among all of the VOCs tested, all of the aromatic compounds significantly produced skin microvascular leakage that was similar to formalin and capsaicin. We also investigated the skin responses seen after the intravenous administration of CP-99,994 (1.5 or 5mg/kg), which is a tachykinin NK1 receptor antagonist, ketotifen (1 or 3mg/kg), which is a histamine H1 receptor antagonist that stabilizes the mast cells, and the topical application of capsazepine (22.5 or 50mM), which is the transient receptor potential vanilloid 1 (TRPV1) antagonist. The response induced by formalin and capsaicin was completely inhibited by CP-99,994. On the other hand, the antagonist partially reduced the response induced by m-xylene, toluene and styrene by 39%, 50% and 46%, respectively. Capsazepine and ketotifen did not alter the response induced by formalin or any of the aromatic compounds. Like capsaicin, formalin and the aromatic compounds at least partially caused skin microvascular leakage, which was due to tachykinin NK1 receptor activation related to the release of tachykinins from the sensory nerve endings. However, it is unlikely that mast cells and TRPV1 play an important role in the skin response.

  10. Probe pressure effects on human skin diffuse reflectance and fluorescence spectroscopy measurements.

    Science.gov (United States)

    Lim, Liang; Nichols, Brandon; Rajaram, Narasimhan; Tunnell, James W

    2011-01-01

    Diffuse reflectance and fluorescence spectroscopy are popular research techniques for noninvasive disease diagnostics. Most systems include an optical fiber probe that transmits and collects optical spectra in contact with the suspected lesion. The purpose of this study is to investigate probe pressure effects on human skin spectroscopic measurements. We conduct an in-vivo experiment on human skin tissue to study the short-term (30 s) effects of probe pressure on diffuse reflectance and fluorescence measurements. Short-term light probe pressure (P0<9 mN∕mm2) effects are within 0 ± 10% on all physiological properties extracted from diffuse reflectance and fluorescence measurements, and less than 0±5% for diagnostically significant physiological properties. Absorption decreases with site-specific variations due to blood being compressed out of the sampled volume. Reduced scattering coefficient variation is site specific. Intrinsic fluorescence shows a large standard error, although no specific pressure-related trend is observed. Differences in tissue structure and morphology contribute to site-specific probe pressure effects. Therefore, the effects of pressure can be minimized when the pressure is small and applied for a short amount of time; however, long-term and large pressures induce significant distortions in measured spectra. PMID:21280899

  11. Stem cell recovering effect of copper-free GHK in skin.

    Science.gov (United States)

    Choi, Hye-Ryung; Kang, Youn-A; Ryoo, Sun-Jong; Shin, Jung-Won; Na, Jung-Im; Huh, Chang-Hun; Park, Kyoung-Chan

    2012-11-01

    The peptide Gly-His-Lys (GHK) is a naturally occurring copper(II)-chelating motifs in human serum and cerebrospinal fluid. In industry, GHK (with or without copper) is used to make hair and skin care products. Copper-GHK plays a physiological role in the process of wound healing and tissue repair by stimulating collagen synthesis in fibroblasts. We also reported that copper-GHK promotes the survival of basal stem cells in the skin. However, the effects of copper-free GHK (GHK) have not been investigated well. In this study, the effects of GHK were studied using cultured normal human keratinocytes and skin equivalent (SE) models. In monolayer cultured keratinocytes, GHK increased the proliferation of keratinocytes. When GHK was added during the culture of SE models, the basal cells became more cuboidal than control model. In addition, there was linear and intense staining of α6 and β1 integrin along the basement membrane. The number of p63 and proliferating cell nuclear antigen positive cells was also significantly increased in GHK-treated SEs than in control SEs. Western blot and slide culture experiment showed that GHK increased the expression of integrin by keratinocytes. All these results showed that GHK increased the stemness and proliferative potential of epidermal basal cells, which is associated with increased expression of integrin. In conclusion, copper-free GHK showed similar effects with copper-GHK. Thus, it can be said that copper-free GHK can be used in industry to obtain the effects of copper-GHK in vivo. Further study is necessary to explore the relationship between copper-free GHK and copper-GHK. PMID:23019153

  12. Anomalous atomic volume of alpha-Pu

    DEFF Research Database (Denmark)

    Kollar, J.; Vitos, Levente; Skriver, Hans Lomholt

    1997-01-01

    .3%. The comparison between the LDA and GGA results show that the anomalously large atomic volume of alpha-Pu relative to alpha-Np can be ascribed to exchange-correlation effects connected with the presence of low coordinated sites in the structure where the f electrons are close to the onset of localization...

  13. Disentangling the Effects of Thickness of the Neutron Skin and Symmetry Potential in Nucleon Induced Reactions on Sn Isotopes

    Institute of Scientific and Technical Information of China (English)

    OU Li; LI Zhu-Xia; WU Xi-Zhen; SUN Wei-Li

    2009-01-01

    The effects of density dependence of symmetry energy and the thickness of the neutron skin in proton (neutron)induced reactions on Sn isotopes are investigated by means of the improved molecular dynamics model. The investigation shows that the target size dependence of the reaction cross sections for proton induced reactions on Sn isotopes is sensitive to the density dependence of the symmetry energy and less sensitive to the thickness of the neutron skin of the target nuclei, but that, for neutron induced reactions on Sn isotopes, it is less sensitive to the density dependence of the symmetry energy and sensitive to the thickness of the neutron skin of the target nucleus.

  14. Effect of a quality-controlled fermented nutraceutical on skin aging markers: An antioxidant-control, double-blind study

    OpenAIRE

    BERTUCCELLI, GIUSEPPE; Zerbinati, Nicola; Marcellino, Massimiliano; NANDA KUMAR, NAVALPUR SHANMUGAM; He, Fang; TSEPAKOLENKO, VLADIMIR; Cervi, Joseph; LORENZETTI, ALDO; Marotta, Francesco

    2016-01-01

    The aim of the present study was to determine whether oral supplementation with a fermented papaya preparation (FPP-treated group) or an antioxidant cocktail (antioxidant-control group, composed of 10 mg trans-resveratrol, 60 µg selenium, 10 mg vitamin E and 50 mg vitamin C) was able to improve the skin antioxidant capacity and the expression of key skin genes, while promoting skin antiaging effects. The study enrolled 60 healthy non-smoker males and females aged 40–65 years, all of whom show...

  15. The effects of delta1-cortienic acid on skin blanching, pharmacokinetics and stability of loteprednol etabonate.

    Science.gov (United States)

    Wu, W M; Bodor, E T; Howes, J; Bodor, N

    2012-05-01

    The effect of delta1-cortienic acid (delta1-CA) on human skin blanching activity of the soft corticosteroid, loteprednol etabonate (LE), has been studied. Ten volunteers had applied to their forearms a dose of LE ranging from 0.1 to 1 mM, or LE from 0.1 to 1 mM in combination with 2-times the concentration of delta1-CA (0.2 - 2mM). The results indicate that delta1-CA increased LE's effect on human vasoconstriction/skin blanching activity, both in the intensity and duration. This enhancing effect of delta1-CA was also observed in other blanching studies with other corticosteroids, such as hydrocortisone. The enhancement may occur through the displacement of LE bound to transcortin (also known as corticosteroid-binding globulin, or CBG) by delta1-CA as delta1-CA has a higher affinity for CBG than that for glucocorticoid receptor (GR), resulting in more free-LE to act on GR, and increased skin blanching. In rat studies, intravenous injection of delta1-CA (5-50 mg/kg) did not affect the pharmacokinetics of LE (5 mg/kg), indicating that delta1-CA is safe for combined use with LE. In stability studies, the presence of delta1-CA at the same concentrations as LE in aqueous suspension (0.1 and 0.2%) significantly increased the stability of LE. Thus, the combination of delta1-CA with LE serves an enhancing and stabilizing role while not impacting the pharmacokinetic properties of LE.

  16. Anomalous radiative transitions

    CERN Document Server

    Ishikawa, Kenzo; Tobita, Yutaka

    2014-01-01

    Anomalous transitions involving photons derived by many-body interaction of the form, $\\partial_{\\mu} G^{\\mu}$, in the standard model are studied. This does not affect the equation of motion in the bulk, but makes wave functions modified, and causes the unusual transition characterized by the time-independent probability. In the transition probability at a time-interval T expressed generally in the form $P=T \\Gamma_0 +P^{(d)}$, now with $\\Gamma_0=0, P^{(d)} \

  17. Biostimulative effects of 809 nm diode laser on cutaneous skin wounds

    Science.gov (United States)

    Solmaz, Hakan; Gülsoy, Murat; Ülgen, Yekta

    2015-03-01

    The use of low-level laser therapy (LLLT) for therapeutic purposes in medicine has become widespread recently. There are many studies in literature supporting the idea of therapeutic effects of laser irradiation on biological tissues. The aim of this study is to investigate the biostimulative effect of 809nm infrared laser irradiation on the healing process of cutaneous incisional skin wounds. 3-4 months old male Wistar Albino rats weighing 300 to 350 gr were used throughout this study. Lowlevel laser therapy was applied through local irradiation of 809nm infrared laser on open skin incisional wounds of 1 cm length. Each animal had six identical incisions on their right and left dorsal region symmetrical to each other. The wounds were separated into three groups of control, 1 J/cm2 and 3 J/cm2 of laser irradiation. Two of these six wounds were kept as control group and did not receive any laser application. Rest of the incisions was irradiated with continuous diode laser of 809nm in wavelength and 20mW power output. Two of them were subjected to laser irradiation of 1 J/cm2 and the other two were subjected to laser light with energy density of 3 J/cm2. Biostimulation effects of irradiation were studied by means of tensile strength tests and histological examinations. Wounded skin samples were morphologically examined and removed for mechanical and histological examinations at days 3, 5 and 7 following the laser applications. Three of the six fragments of skin incisions including a portion of peripheral healthy tissue from each animal were subjected to mechanical tests by means of a universal tensile test machine, whereas the other three samples were embedded in paraffin and stained with hematoxylin and eosin for histological examinations. The findings of the study show that tissue repair following laser irradiation of 809nm has been accelerated in terms of tissue morphology, strength and cellular content. These results seem to be consistent with the results of many

  18. Ultrastructural Study on Ultra-Low Frequency Electromagnetic Fields and Transfer Factor Effects on Skin Ulcers

    Science.gov (United States)

    Cadena, M. S. Reyes; Chapul, L. Sánchez; Pérez, Javiér; García, M. N. Jiménez; López, M. A. Jiménez; Espíndola, M. E. Sánchez; Perez, R. Paniagua; Hernández, N. A.; Paniagua, G.; Uribe, F.; Nava, J. J. Godina; Segura, M. A. Rodríguez

    2008-08-01

    We determined the effect of 120Hz ultra low frequency electromagnetic field (ELF) on the healing process of skin in 20 Wistar rats distributed in four groups in which chronic dermal ulcers had been produced. The first two groups received a dose of the transfer factor and interferon-beta (IFN-β) every 24 h during 12 days. The third group (positive control) received only electromagnetic field (ELF) sessions, and in the fourth group (negative control), no treatment was applied. The electromagnetic field was applied through a Helmholtz coils; 30 Gauss of intensity. Results shown histological changes that improve the healing process in animals subjected to ELF together with the transfer factor.

  19. The Effects of Nerve Growth Factor on Skin Healing and Blood Recovery in Irradiated Mice

    Institute of Scientific and Technical Information of China (English)

    史春梦; 程天民; 屈纪富

    2002-01-01

    @@ It is known that radiation could cause bone marrow aplasia and delay wound healing.To promote cellular proliferation and blood recovery are 2 major goals in the treatment of radiation injury.We have observed that the expression of nerve growth factor (NGF) gene decreased greatly in the wound tissue of irradiated animals by immunohistochemistry and in situ hybridization methods.This study was designed to elucidate the effects of NGF on the skin wound healing and blood recovery in mice after total body irradiation.

  20. A review of nicotinamide: treatment of skin diseases and potential side effects.

    Science.gov (United States)

    Rolfe, Heidi M

    2014-12-01

    Nicotinamide, also known as niacinamide, is the amide form of vitamin B3. It is a precursor of essential coenzymes for numerous reactions in the body including adenosine triphosphate (ATP) production. Nicotinic acid, also known as niacin, is converted into nicotinamide in the body. The use of topical nicotinamide in the treatment of acne vulgaris; melasma; atopic dermatitis; rosacea; and oral nicotinamide in preventing nonmelanoma skin cancer is discussed. The possible side effects and consequences of excessive nicotinamide exposure are reviewed, including suggestions nicotinamide might have a role in the development of diabetes, Parkinson's disease, and liver damage.