Autour de Nikolaï Leskov et de William Shakespeare : Lady Macbeth sibérienne d'Andrzej Wajda

OpenAIRE

Géry, Catherine

2016-01-01

Lady Macbeth sibérienne d’Andrzej Wajda est un film qui joue constamment de codes plus ou moins conflictuels : cinéma et théâtre (William Shakespeare), mais aussi cinéma et opéra (Dmitri Chostakovitch), cinéma et conte oral (Nikolaï Leskov). Cultivant le dialogue entre les genres et les discours esthétiques, il est également au croisement des cultures et des époques. Dans ce chapitre, j’envisage la théâtralité du film de Wajda selon plusieurs de ses définitions possibles : la théâtralité comm...

New Nordic Exceptionalism: Jeuno JE Kim and Ewa Einhorn's The United Nations of Norden and other realist utopias

Directory of Open Access Journals (Sweden)

Mathias Danbolt

2016-11-01

Full Text Available At the 2009 Nordic Culture Forum summit in Berlin that centered on the profiling and branding of the Nordic region in a globalized world, one presenter stood out from the crowd. The lobbyist Annika Sigurdardottir delivered a speech that called for the establishment of “The United Nations of Norden”: A Nordic union that would gather the nations and restore Norden's role as the “moral superpower of the world.” Sigurdardottir's presentation generated such a heated debate that the organizers had to intervene and reveal that the speech was a performance made by the artists Jeuno JE Kim and Ewa Einhorn. This article takes Kim and Einhorn's intervention as a starting point for a critical discussion of the history and politics of Nordic image-building. The article suggests that the reason Kim and Einhorn's speech passed as a serious proposal was due to its meticulous mimicking of two discursive formations that have been central to the debates on the branding of Nordicity over the last decades: on the one hand, the discourse of “Nordic exceptionalism,” that since the 1960s has been central to the promotion of a Nordic political, socio-economic, and internationalist “third way” model, and, on the other hand, the discourse on the “New Nordic,” that emerged out of the New Nordic Food-movement in the early 2000s, and which has given art and culture a privileged role in the international re-fashioning of the Nordic brand. Through an analysis of Kim and Einhorn's United Nations of Norden (UNN-performance, the article examines the historical development and ideological underpinnings of the image of Nordic unity at play in the discourses of Nordic exceptionalism and the New Nordic. By focusing on how the UNN-project puts pressure on the role of utopian imaginaries in the construction of Nordic self-images, the article describes the emergence of a discursive framework of New Nordic Exceptionalism.

An epigenome-wide association study in whole blood of measures of adiposity among Ghanaians: the RODAM study

NARCIS (Netherlands)

Meeks, Karlijn A. C.; Henneman, Peter; Venema, Andrea; Burr, Tom; Galbete, Cecilia; Danquah, Ina; Schulze, Matthias B.; Mockenhaupt, Frank P.; Owusu-Dabo, Ellis; Rotimi, Charles N.; Addo, Juliet; Smeeth, Liam; Bahendeka, Silver; Spranger, Joachim; Mannens, Marcel M. A. M.; Zafarmand, Mohammad H.; Agyemang, Charles; Adeyemo, Adebowale

2017-01-01

Background: Epigenome-wide association studies (EWAS) have identified DNA methylation loci involved in adiposity. However, EWAS on adiposity in sub-Saharan Africans are lacking despite the high burden of adiposity among African populations. We undertook an EWAS for anthropometric indices of

Evaluation of Three Adolescent Sexual Health Programs in Ha Noi and Khanh Hoa Province, Vietnam

Directory of Open Access Journals (Sweden)

Van Pham

2012-01-01

Full Text Available With an increase in sexual activity among young adults in Vietnam and associated risks, there is a need for evidence-based sexual health interventions. This evaluation of three sexual health programs based on the Protection Motivation Theory (PMT was conducted in 12 communes in Ha Noi, Nha Trang City, and Ninh Hoa District. Inclusion criteria included unmarried youth 15–20 years residing in selected communes. Communes were randomly allocated to an intervention, and participants were randomly selected within each commune. The intervention programs included Vietnamese Focus on Kids (VFOK, the gender-based program Exploring the World of Adolescents (EWA, and EWA plus parental and health provider education (EWA+. Programs were delivered over a ten-week period in the communities by locally trained facilitators. The gender-based EWA program with parental involvement (EWA+ compared to VFOK showed significantly greater increase in knowledge. EWA+ in comparison to VFOK also showed significant decrease at immediate postintervention for intention to have sex. Sustained changes are observed in all three interventions for self-efficacy condom use, self-efficacy abstinence, response efficacy for condoms, extrinsic rewards, and perceived vulnerability for HIV. These findings suggest that theory-based community programs contribute to sustained changes in knowledge and attitudes regarding sexual risk among Vietnamese adolescents.

Evaluation of three adolescent sexual health programs in ha noi and khanh hoa province, Vietnam.

Science.gov (United States)

Pham, Van; Nguyen, Hoang; Tho, Le Huu; Minh, Truong Tan; Lerdboon, Porntip; Riel, Rosemary; Green, Mackenzie S; Kaljee, Linda M

2012-01-01

With an increase in sexual activity among young adults in Vietnam and associated risks, there is a need for evidence-based sexual health interventions. This evaluation of three sexual health programs based on the Protection Motivation Theory (PMT) was conducted in 12 communes in Ha Noi, Nha Trang City, and Ninh Hoa District. Inclusion criteria included unmarried youth 15-20 years residing in selected communes. Communes were randomly allocated to an intervention, and participants were randomly selected within each commune. The intervention programs included Vietnamese Focus on Kids (VFOK), the gender-based program Exploring the World of Adolescents (EWA), and EWA plus parental and health provider education (EWA+). Programs were delivered over a ten-week period in the communities by locally trained facilitators. The gender-based EWA program with parental involvement (EWA+) compared to VFOK showed significantly greater increase in knowledge. EWA+ in comparison to VFOK also showed significant decrease at immediate postintervention for intention to have sex. Sustained changes are observed in all three interventions for self-efficacy condom use, self-efficacy abstinence, response efficacy for condoms, extrinsic rewards, and perceived vulnerability for HIV. These findings suggest that theory-based community programs contribute to sustained changes in knowledge and attitudes regarding sexual risk among Vietnamese adolescents.

Film, mis mõjub / Anne Applebaum ; tõlk. Kaarel Tarand

Index Scriptorium Estoniae

Applebaum, Anne

2008-01-01

Ajalehes The New York Review of Books (14. II) ilmunud artikkel poola režissööri Andrzej Wajda filmist "Katõn", mis räägib Katõni massimõrvast. Andrzej Wajda pälvis sel aastal Eesti presidendilt Maarjamaa Risti III klassi teenetemärgi

Poola Nike 2008 / Hendrik Lindepuu

Index Scriptorium Estoniae

Lindepuu, Hendrik

2008-01-01

Poola mainekaima kirjandusauhinna Nike pälvis tänavu Olga Tokarczuki romaan "Jooksjad". Nominendid olid veel: Bronislaw Swiderski "Surma assistent", Krzysztof Varga "Hauakivi terrasiidiga", Andrzej Sosnowski "Pärast vikerkaart", Andrzej Szczeklik "Kore. Haigetest, haigusest ja hinge otsinguist", Wlodzimierz Nowaki "Pea ümbermõõt" ja Malgorzata Szejnerti "Must aed"

Sharing Water with Nature: Insights on Environmental Water Allocation from a Case Study of the Murrumbidgee Catchment, Australia

Directory of Open Access Journals (Sweden)

Becky Swainson

2011-02-01

Full Text Available Human use of freshwater resources has placed enormous stress on aquatic ecosystems in many regions of the world. At one time, this was considered an acceptable price to pay for economic growth and development. Nowadays, however, many societies are seeking a better balance between healthy aquatic ecosystems and viable economies. Unfortunately, historically, water allocation systems have privileged human uses over the environment. Thus, jurisdictions seeking to ensure that adequate water is available for the environment must typically deal with the fact that economies and communities have become dependent on water. Additionally, they must often layer institutions for environmental water allocation (EWA on top of already complex institutional systems. This paper explores EWA in a jurisdiction – New South Wales (NSW, Australia – where water scarcity has become a priority. Using an in-depth case study of EWA in the Murrumbidgee catchment, NSW, we characterise the NSW approach to EWA with the goal of highlighting the myriad challenges encountered in EWA planning and implementation. Sharing water between people and the environment, we conclude, is much more than just a scientific and technical challenge. EWA in water-scarce regions involves reshaping regional economies and societies. Thus, political and socio-economic considerations must be identified and accounted for from the outset of planning and decision-making processes.

Managing water to protect fish: A review of California's environmental water account, 2001-2005

Science.gov (United States)

Brown, L.R.; Kimmerer, W.; Brown, R.

2009-01-01

The Sacramento-San Joaquin Delta, the landward reach of the San Francisco Estuary, provides habitat for threatened delta smelt, endangered winter-run Chinook salmon, and other species of concern. It is also the location of huge freshwater diversion facilities that entrain large numbers of fish. Reducing the entrainment of listed fishes into these facilities has required curtailment of pumping, reducing the reliability of water deliveries. We reviewed the first 5 years (2001-2005) of the Environmental Water Account (EWA), a program instituted to resolve conflicts between protecting listed fishes and providing a reliable water supply. The EWA provided fishery agencies with control over 0.2-0.4 km3 of water to be used for fish protection at no cost to users of exported water, and fish agencies guaranteed no disruption of water supply for fish protection. The EWA was successful in reducing uncertainty in water supply; however, its contribution to the recovery of listed fishes was unclear. We estimated the effectiveness of the EWA to be modest, increasing the survival of winter-run Chinook salmon by 0-6% (dependent on prescreen mortality), adult delta smelt by 0-1%, and juvenile delta smelt by 2-4%. Allocating EWA water for a single life stage of one species could provide larger gains in survival. An optimally allocated EWA of equal size to the median of the first 5 years could increase abundance of juvenile delta smelt up to 7% in the springs of dry years. If the EWA is to become a long-term program, estimates of efficacy should be refined. If the program is to be held accountable for quantitative increases in fish populations, it will be necessary to integrate scientific, possibly experimental, approaches. ?? 2008 Springer Science+Business Media, LLC.

eFORGE : A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data

NARCIS (Netherlands)

Breeze, Charles E.; Paul, Dirk S.; van Dongen, Jenny; Butcher, Lee M.; Ambrose, John C.; Barrett, James E.; Lowe, Robert; Rakyan, Vardhman K.; Iotchkova, Valentina; Frontini, Mattia; Downes, Kate; Ouwehand, Willem H.; Laperle, Jonathan; Jacques, Pierre-ETienne; Bourque, Guillaume; Bergmann, Anke K.; Siebert, Reiner; Vellenga, Edo; Saeed, Sadia; Matarese, Filomena; Martens, Joost H. A.; Stunnenberg, Hendrik G.; Teschendorff, Andrew E.; Herrero, Javier; Birney, Ewan; Dunham, Ian; Beck, Stephan

2016-01-01

Epigenome-wide association studies (EWAS) provide an alternative approach for studying human disease through consideration of non-genetic variants such as altered DNA methylation. To advance the complex interpretation of EWAS, we developed eFORGE (http://eforge.cs.ucl.ac.uk/), a new stand-alone and

Professor Andrzej Nespiak (1921-1981

Directory of Open Access Journals (Sweden)

Tomasz Majewski

2014-08-01

Full Text Available The biography of a professor of the Laboratory of Pharmaceutical Botany of the Medical Academy in Wrocław, who was formerly an investigator of the Agricultural Academy in Wrocław. He worked on mycorhiza, the participation of Macromycetes in forest communities and the use of fungi for synthesis of some organic compounds, he was also the author of the Polish flora of the genus Cortinarius (1975,1981 and Inocybe (manuscript.

Professor Andrzej Nespiak (1921-1981)

OpenAIRE

Tomasz Majewski

2014-01-01

The biography of a professor of the Laboratory of Pharmaceutical Botany of the Medical Academy in Wrocław, who was formerly an investigator of the Agricultural Academy in Wrocław. He worked on mycorhiza, the participation of Macromycetes in forest communities and the use of fungi for synthesis of some organic compounds, he was also the author of the Polish flora of the genus Cortinarius (1975,1981) and Inocybe (manuscript).

The Design and Analysis of Efficient Learning Algorithms

Science.gov (United States)

1991-01-01

31] describe in detail how this can be done efficiently; see also Duda and Hart [22]. Let a&,..., &d be the resulting solution, and let h0 = Fd=1 af...Measure. Wiley, second edition, 1986. [13] Anselm Blumer, Andrzej Ehrenfeucht, David Haussler, and Manfred K. Warmuth. Occam’s razor. Information...Processing Letters, 24(6):377-380, April 1987. [14] Anselm Blumer, Andrzej Ehrenfeucht, David Haussler, and Manfred K. Warmuth. Learn- ability and the

In-situ growth of AuNPs on WS2@U-bent optical fiber for evanescent wave absorption sensor

Science.gov (United States)

Zhang, Suzhen; Zhao, Yuefeng; Zhang, Chao; Jiang, Shouzhen; Yang, Cheng; Xiu, Xianwu; Li, Chonghui; Li, Zhen; Zhao, Xiaofei; Man, Baoyuan

2018-05-01

The sensitivity of the evanescent wave absorption sensor is always a hot topic which has been attracted researchers' discussion. It is still a challenge for developing the effective sensor to sensitively detect some biochemical molecules solution in a simple and low-cost way. In this paper, an evanescent wave absorption (EWA) sensor has been presented based on the U-bent multimode fiber coated with tungsten disulfide (WS2) film and in-situ growth of gold nanoparticles (AuNPs) for the detection of ethanol solution and sodium chloride (NaCl) solution. Benefitted from the effective light coupling produced between U-bent probe and AuNPs, we attained the optimal size of the AuNPs by changing the reaction time between WS2 and tetrachloroauric acid (HAuCl4). With the AuNPs/WS2@U-bent optical fiber, we discussed the behaviors of EWA sensor, such as sensitivity, reproducibility, fast response-recovery time and stability. The sensitivity (△A/△C) of the proposed AuNPs/WS2@U-bent optical fiber EWA sensor is 0.65 for the detection of the ethanol solution. Besides, the AuNPs/WS2@U-bent optical fiber EWA sensor exhibits high sensitivity in detection of the sodium chloride (NaCl), which can reach 1.5 when the proposed sensor was immersed into NaCl solution. Our work demonstrates that the U-bent optical fiber EWA sensor may have promising applications in testing the solution of concentration.

Proceedings of the Army Science Conference (15th) Held at West Point, New York on 17-19 June 1986. Volume 2. Principal Authors H through L.

Science.gov (United States)

1986-06-20

Miziolek, Andrzej W. Mescall, John F. Improved Modeling of Fracture in Il 41 .. ii. Tracy, Carl Ceramic Armors Meyer, Fred P. Hardening of High Silica...Mitchell, Glen W. See Simmons, Ronald IV 127 ’ ... Miziolek, Andrzej W. See Melius, Carl F. Il 25 Moerkirk, Robert P. See Ross, Raymond L. Ill 299...Trans. Comput., Vol. C-21, pp. 179-1 86. 4. Duda , R.Oo and P.E. Hart (1973) Pattern Classification and Scene Analysis, John Wiley & Sons, New York. 5

Energy Efficiency in Computing (1/2)

CERN Multimedia

CERN. Geneva

2016-01-01

As manufacturers improve the silicon process, truly low energy computing is becoming a reality - both in servers and in the consumer space. This series of lectures covers a broad spectrum of aspects related to energy efficient computing - from circuits to datacentres. We will discuss common trade-offs and basic components, such as processors, memory and accelerators. We will also touch on the fundamentals of modern datacenter design and operation. Lecturer's short bio: Andrzej Nowak has 10 years of experience in computing technologies, primarily from CERN openlab and Intel. At CERN, he managed a research lab collaborating with Intel and was part of the openlab Chief Technology Office. Andrzej also worked closely and initiated projects with the private sector (e.g. HP and Google), as well as international research institutes, such as EPFL. Currently, Andrzej acts as a consultant on technology and innovation with TIK Services (http://tik.services), and runs a peer-to-peer lending start-up. NB! All Academic L...

Gamma camera scatter suppression unit WAM

International Nuclear Information System (INIS)

Kishi, Haruo; Shibahara, Noriyuki; Hirose, Yoshiharu; Shimonishi, Yoshihiro; Oumura, Masahiro; Ikeda, Hozumi; Hamada, Kunio; Ochi, Hironobu; Itagane, Hiroshi.

1990-01-01

In gamma camera imaging, scattered radiation is one of big factors to decrease image contrast. Simply, scatter suppression makes signal to noise ratio larger, but it makes statistics error because of radionuclide injection limit to the human body. EWA is a new method that suppresses scattered radiation and improves image contrast. In this article, WAM which is commercialized EWA method by Siemens Gammasonics Inc. is presented. (author)

Swimming Against the Current: A Qualitative Review of the Work Experiences and Adaptations made by Employees with Arthritis.

Science.gov (United States)

Purc-Stephenson, R J; Dostie, Jessica; Smith, Hailey J

2018-01-30

To describe the experiences and strategies of employees with arthritis (EwA) to maintain employment and to use this information to build a conceptual model. We conducted a systematic review of qualitative studies that examined the work experiences of EwA. Published studies on arthritis and employment were searched from electronic databases (1980-2017) and bibliographical reviews of relevant studies. We used meta-ethnography to synthesize the findings. We reviewed 17 studies reporting on the experiences of 873 employees. We identified 11 main themes that highlight common issues experienced by EwA, and grouped these into four higher-order categories: nature of the disease (emotional issues, cognitive struggles, physical symptoms), intrapersonal issues (personal meaning of work, preserving a work identity), interpersonal issues (managing disclosure, gaining co-worker support, organizational culture issues), and work-sustainability strategies (making personal adjustments, using social support, using workplace accommodations). Using these themes, we developed the Job Sustainability Model to illustrate how disease, personal, and work-related factors interact to influence what type of coping behaviors are used and when. Initially, EwA rely on making personal adjustments, using social support, and medical intervention. However, when these coping behaviors fail to be effective, they draw upon workplace accommodations and resources. Arthritis disrupts an employee's work life by impairing his or her capacity to be a productive worker. Our results highlight how EwA make strategic adaptations to maintain a productive work life for as long as possible. The findings of this study have implications for work-related interventions aimed at preserving employment. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Energy Efficiency in Computing (2/2)

CERN Multimedia

CERN. Geneva

2016-01-01

We will start the second day of our energy efficient computing series with a brief discussion of software and the impact it has on energy consumption. A second major point of this lecture will be the current state of research and a few future technologies, ranging from mainstream (e.g. the Internet of Things) to exotic. Lecturer's short bio: Andrzej Nowak has 10 years of experience in computing technologies, primarily from CERN openlab and Intel. At CERN, he managed a research lab collaborating with Intel and was part of the openlab Chief Technology Office. Andrzej also worked closely and initiated projects with the private sector (e.g. HP and Google), as well as international research institutes, such as EPFL. Currently, Andrzej acts as a consultant on technology and innovation with TIK Services (http://tik.services), and runs a peer-to-peer lending start-up. NB! All Academic Lectures are recorded. No webcast! Because of a problem of the recording equipment, this lecture will be repeated for recording pu...

A new automatic algorithm for quantification of myocardial infarction imaged by late gadolinium enhancement cardiovascular magnetic resonance: experimental validation and comparison to expert delineations in multi-center, multi-vendor patient data.

Science.gov (United States)

Engblom, Henrik; Tufvesson, Jane; Jablonowski, Robert; Carlsson, Marcus; Aletras, Anthony H; Hoffmann, Pavel; Jacquier, Alexis; Kober, Frank; Metzler, Bernhard; Erlinge, David; Atar, Dan; Arheden, Håkan; Heiberg, Einar

2016-05-04

Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) using magnitude inversion recovery (IR) or phase sensitive inversion recovery (PSIR) has become clinical standard for assessment of myocardial infarction (MI). However, there is no clinical standard for quantification of MI even though multiple methods have been proposed. Simple thresholds have yielded varying results and advanced algorithms have only been validated in single center studies. Therefore, the aim of this study was to develop an automatic algorithm for MI quantification in IR and PSIR LGE images and to validate the new algorithm experimentally and compare it to expert delineations in multi-center, multi-vendor patient data. The new automatic algorithm, EWA (Expectation Maximization, weighted intensity, a priori information), was implemented using an intensity threshold by Expectation Maximization (EM) and a weighted summation to account for partial volume effects. The EWA algorithm was validated in-vivo against triphenyltetrazolium-chloride (TTC) staining (n = 7 pigs with paired IR and PSIR images) and against ex-vivo high resolution T1-weighted images (n = 23 IR and n = 13 PSIR images). The EWA algorithm was also compared to expert delineation in 124 patients from multi-center, multi-vendor clinical trials 2-6 days following first time ST-elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention (PCI) (n = 124 IR and n = 49 PSIR images). Infarct size by the EWA algorithm in vivo in pigs showed a bias to ex-vivo TTC of -1 ± 4%LVM (R = 0.84) in IR and -2 ± 3%LVM (R = 0.92) in PSIR images and a bias to ex-vivo T1-weighted images of 0 ± 4%LVM (R = 0.94) in IR and 0 ± 5%LVM (R = 0.79) in PSIR images. In multi-center patient studies, infarct size by the EWA algorithm showed a bias to expert delineation of -2 ± 6 %LVM (R = 0.81) in IR images (n = 124) and 0 ± 5%LVM (R = 0.89) in

DNA Methylation Patterns in Cord Blood of Neonates Across Gestational Age: Association With Cell-Type Proportions.

Science.gov (United States)

Braid, Susan M; Okrah, Kwame; Shetty, Amol; Corrada Bravo, Hector

A statistical methodology is available to estimate the proportion of cell types (cellular heterogeneity) in adult whole blood specimens used in epigenome-wide association studies (EWAS). However, there is no methodology to estimate the proportion of cell types in umbilical cord blood (also a heterogeneous tissue) used in EWAS. The objectives of this study were to determine whether differences in DNA methylation (DNAm) patterns in umbilical cord blood are the result of blood cell type proportion changes that typically occur across gestational age and to demonstrate the effect of cell type proportion confounding by comparing preterm infants exposed and not exposed to antenatal steroids. We obtained DNAm profiles of cord blood using the Illumina HumanMethylation27k BeadChip array for 385 neonates from the Boston Birth Cohort. We estimated cell type proportions for six cell types using the deconvolution method developed by . The cell type proportion estimates segregated into two groups that were significantly different by gestational age, indicating that gestational age was associated with cell type proportion. Among infants exposed to antenatal steroids, the number of differentially methylated CpGs dropped from 127 to 1 after controlling for cell type proportion. EWAS utilizing cord blood are confounded by cell type proportion. Careful study design including correction for cell type proportion and interpretation of results of EWAS using cord blood are critical.

Ergonomic analysis in the manual transport of loads: a case study in a cement production company

Directory of Open Access Journals (Sweden)

Jarbas Rocha Martins

2017-03-01

Full Text Available This study aims to analyze the manual transport activity of 50kg bags in a cement production company by means of ergonomic work analysis (EWA, identifying environmental factors and loaders’ working conditions. In order for EWA to take place, photographic records, videos and interviews were performed. It covered aspects related to lifting, transportation and handling of cement bags, as well as observations of loaders’ posture while performing the activity. In this sense, both qualitative and quantitative aspects were taken into account, which were evidenced by the use of instruments for determining the concentration of agents in the environment. In addition, some management tools, such as the cause and effect diagram, and interviews conducted during the field research were used. It was found that the high rate of absenteeism in the activity is related to the strict control of productivity, the excessive lifting and manual transport of weights, and repetitive trunk flexion movements. The results shown by the EWA made it possible to propose preventive measures and some changes in the work environment.

[Umgesiedelt - Vertrieben. Deutschbalten und Polen 1939-1945 im Warthegau] / Karsten Brüggemann

Index Scriptorium Estoniae

Brüggemann, Karsten, 1965-

2012-01-01

Arvustus: Umgesiedelt - Vertrieben. Deutschbalten und Polen 1939-1945 im Warthegau / hrsg. von Eckhart Neander und Andrzej Sakson. Marburg : Verlag Herder-Institut 2010. (Tagungen zur Ostmitteleuropa-Forschung, 29)

Sündmused leiavad aset ikka inimese peas, mitte rahakotis / Tiit Palu ; interv. Margot Visnap

Index Scriptorium Estoniae

Palu, Tiit, 1970-

2008-01-01

Endla teatri eesseisvast hooajast, teatri majanduslikust olukorrast. Riias Balti teatrifestivalil etendunud Kalju Komissarovi lavastusest "Kangelane", 4. oktoobril esietenduvast Andrzej Saramonowiczi komöödiast "Testosteroon" ja teistest uuslavastustest lühidalt

Comparison of projection skills of deterministic ensemble methods using pseudo-simulation data generated from multivariate Gaussian distribution

Science.gov (United States)

Oh, Seok-Geun; Suh, Myoung-Seok

2017-07-01

The projection skills of five ensemble methods were analyzed according to simulation skills, training period, and ensemble members, using 198 sets of pseudo-simulation data (PSD) produced by random number generation assuming the simulated temperature of regional climate models. The PSD sets were classified into 18 categories according to the relative magnitude of bias, variance ratio, and correlation coefficient, where each category had 11 sets (including 1 truth set) with 50 samples. The ensemble methods used were as follows: equal weighted averaging without bias correction (EWA_NBC), EWA with bias correction (EWA_WBC), weighted ensemble averaging based on root mean square errors and correlation (WEA_RAC), WEA based on the Taylor score (WEA_Tay), and multivariate linear regression (Mul_Reg). The projection skills of the ensemble methods improved generally as compared with the best member for each category. However, their projection skills are significantly affected by the simulation skills of the ensemble member. The weighted ensemble methods showed better projection skills than non-weighted methods, in particular, for the PSD categories having systematic biases and various correlation coefficients. The EWA_NBC showed considerably lower projection skills than the other methods, in particular, for the PSD categories with systematic biases. Although Mul_Reg showed relatively good skills, it showed strong sensitivity to the PSD categories, training periods, and number of members. On the other hand, the WEA_Tay and WEA_RAC showed relatively superior skills in both the accuracy and reliability for all the sensitivity experiments. This indicates that WEA_Tay and WEA_RAC are applicable even for simulation data with systematic biases, a short training period, and a small number of ensemble members.

Therapy of psoriasis with narrowband ultraviolet-B light influences plasma concentrations of MMP-2 and TIMP-2 in patients

Directory of Open Access Journals (Sweden)

Głażewska EK

2016-10-01

Full Text Available Edyta Katarzyna Głażewska,1 Marek Niczyporuk,1 Sławomir Ławicki,2 Maciej Szmitkowski,2 Monika Zajkowska,2 Grażyna Ewa Będkowska,3 Andrzej Przylipiak1 1Department of Esthetic Medicine, 2Department of Biochemical Diagnostics, 3Department of Haematological Diagnostics, Medical University, Białystok, Poland Background: Matrix metalloproteinases (MMPs, which show a significant ability to cleave the components of extracellular matrix, and tissue inhibitors of metalloproteinases (TIMPs, which slow down the activity of those enzymes, may be implicated in the pathogenesis and spread of psoriatic disease. This study aims to analyze plasma levels of MMP-2 and TIMP-2 in plaque psoriasis patients before and after the course of narrowband ultraviolet-B (NBUVB therapy with respect to disease advancement. Patients and methods: A total of 49 patients suffering from plaque psoriasis and 40 healthy volunteers were enrolled into the study. Plasma levels of MMP-2 and TIMP-2 were determined using enzyme-linked immunosorbent assay, while Psoriasis Area and Severity Index (PASI was used to define the disease advancement. Results: The results showed increased plasma levels of MMP-2 and TIMP-2, but this change was significant only in case of MMP-2 in total psoriatic group compared to healthy subjects. Moreover, there was an increase in the concentrations of chosen factors with an increase in the severity of the disease. The NBUVB therapy causes a decline in the concentration of the analyzed enzyme and its inhibitor, although this change was statistically significant in the total psoriatic group only in case of MMP-2. There was also a positive correlation between MMP-2, TIMP-2, and PASI score value. Conclusion: Our study highlights a possible important role of MMP-2 in the activity of psoriasis and clearance of disease symptoms. Moreover, plasma MMP-2 seems to be a valuable psoriasis biomarker. Keywords: gelatinase A, matrix metalloproteinases, tissue inhibitor of

Poolakad näitavad etlemiskunsti / Gert Hatsukov ; interv. Johannes Saar

Index Scriptorium Estoniae

Hatsukov, Gert

2004-01-01

Ürituse korraldaja Gert Hatsukoviga poola etlemiskunstnikest Pawel Kwasniewskist, Wladislav Kazmierczakist, Ewa Rybskast, Artur Grabowskist ja Dariusz Fodczukist. Poola etlemiskunsti õhtupoolik "Transmission" toimub Vaal-galeriis

Teatrisügise macho-pähklid / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2008-01-01

Andrzej Saramonowiczi näidend "Testosteroon" Endla teatris, lavastaja Enn Keerd. Ott Aardami noortetükist "Poks", lavastaja autor Ugala teatris. Kristjan Sarve debüütlavastus "Rambo" David Morrelli romaani "Esimene veri" ainetel NO99 teatris

VIP EE, Ms Ene Ergma, President of the Estonia Parliament (Riigikogu), Republic of Estonia (attending the 3rd World Conference of Speakers of Parliament in Geneva)

CERN Multimedia

2010-01-01

She toured the LHC superconducting magnet test hall with Andrzej Siemko, leader of the machine protection and electrical integrity group in the technology department, and also saw the CERN Control Centre, the CMS experiment and the LHC tunnel.

Post mortem : Katõn ja meie enda tõrjutud mälestused / Rauno Thomas Moss

Index Scriptorium Estoniae

Moss, Rauno Thomas

2008-01-01

Poola filmilavastaja Andrzej Wajda mängufilmist "Katõn" (Poola, 2007) ja Imbi Paju dokumentaalfilmist "Tõrjutud mälestused" (Eesti - Soome, 2005). Artikli lõpus mõlema filmi režissööridest ja A. Wajda filmograafia

A Proxy Method for Estimation of EE-index using MAGDAS/CPMN Data

Science.gov (United States)

Ueno, T.; Yumoto, K.; Uozumi, T.; Numata, Y.; Group, M.

2008-12-01

EE-index (EDst, EU, and EL) is a new index proposed by Space Environment Research Center, Kyushu University (see Uozumi et al., 2008) to monitor temporal and long-term variations of the equatorial electrojet (EEJ). EU and EL mainly represent the range of EEJ and CEJ (equatorial counter electrojet) components, respectively. The baseline levels of EU and EL are obtained by averaging the H-component magnetic variations observed at the nightside (LT = 18-06) MAGDAS/CPMN stations along the magnetic equator. EDst, defined by Uozumi et al. (2008) fluctuates depending on the number of stations in the nightside sector (LT = 18-06). If the number is few, EDst may include some local fluctuations: the partial ring current component, substorm component and so on. Such local components cause some error in estimating the baseline level of EU or EL. Therefore, we need to use as many stations' data as possible in order to derive EU and EL properly. Pacific region is one of the most difficult areas to measure the magnetic field near the dip equator, because there are few islands. In the present paper, we developed a new method to use the data obtained from Ewa Beach (EWA; G. Lat. = 21.32N, G. Long. = 158.0W, Dip Lat. = 38.03), Hawaii, USA for estimation of EDst. EWA is not the equatorial station, but its nighttime H-component magnetic variations are found to be similar to those of Christmas Island (CXI; G. Lat. = 2.05N, G. Long. = 157.5W, Dip Lat. = 5.24), Kiribati. Data from EWA can be used as a proxy of that from CXI for monitoring temporal and long-term variations of the equatorial electrojet (EEJ) in real time. Acknowledgements: Authors appreciate Prof. Hisashi Utada of Earthquake Research Institute, University of Tokyo for supplying the magnetometer data from Christmas Island, Kiribati. Our deepest gratitude goes to all the members of the MAGDAS/CPMN project for their ceaseless support. Especially, we wish to thank the staffs of the observation stations: Dr. Baylie Damtie

Barbers Point Sewage Outfall Fish Census from Annual Surveys 1991-2010 (NODC Accession 0073346)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The Honouliuli Wastewater Treatment Plant (WWTP) located in Ewa, Oahu, Hawaii, near Barbers Point (Kalaeloa) has been in operation since 1982. It releases...

"Baltiiski dom 2008" : uvelitshitelnoje steklo / Eteri Kekelidze

Index Scriptorium Estoniae

Kekelidze, Eteri, 1944-

2008-01-01

Peterburis toimunud kaheksteistkümnenda rahvusvahelise teatrifestivali "Baltiiski dom" lavastustest - Kristian Smedsi "Tundmatu sõdur", Alvis Hermanise "Läti rong", Luk Percevali "Kaubareisija surm", Igor Konjajevi "Matke mind põrandaliistu taha" ja Andrzej Bubeni "Vene moos". Ka teater NO99 osalemisest Tiit Ojasoo lavastusega "GEP"

Svoboda 'severnõh Afin' : derptskaja Polonia / Sergei Issakov, Pavel Sigalov

Index Scriptorium Estoniae

Issakov, Sergei, 1931-2013

1997-01-01

Korporatsioonist 'Polonia' (asut. 1828. a.) jt. poola üliõpilaste ühendustest Tartus. Tartu ülikoolis õppinud poola kirjanikest ja kirjandusteadlasest: Alfons Walicki, Aleksander Karol Groza, Edward Zheligowski, Bronislaw Zaleski, Jzef Bohdan Dzienkonski, Ludomir Gadon, Jzef Weyssenhoff, Marian Zdziechowski, Andrzej Niemojewski, Ludwik Bruner, Jerzy Jankowski

Usefulness of problem tree, objective tree and logical framework ...

African Journals Online (AJOL)

user17

ployed if this person is (a) not working, (b) currently available for work and (c) seeking work ... nancial insecurity, indebtedness (Mroz & Savage, 2006), criminality, family ... has been a solution to address unemployment in Persian Gulf (Andrzej, 2000). ... Challenges of higher education to produce employable graduates.

Probabilistic stability and "tall" wind profiles: theory and method for use in wind resource assessment

DEFF Research Database (Denmark)

Kelly, Mark C.; Troen, Ib

2016-01-01

A model has been derived for calculating the aggregate effects of stability and the finite height of the planetary boundary layer upon the long-term mean wind profile. A practical implementation of this probabilistic extended similarity-theory model is made, including its incorporation within...... to the methodology. Results of the modeling are shown for a number of sites, with discussion of the models’ efficacy and the relative improvement shown by the new model, for situations where a user lacks local heat flux information, as well as performance of the new model using measured flux statistics. Further...... the European Wind Atlas (EWA) methodology for site-to-site application. Theoretical and practical implications of the EWA methodology are also derived and described, including unprecedented documentation of the theoretical framework encompassing vertical extrapolation, as well as some improvement...

Homme kell 14 algab Vaala galeriis järjekordse "INPORTi" raames...

Index Scriptorium Estoniae

2004-01-01

Poola kunstnike Dariusz Fodczuki (sünd. 1966), Wladislaw Kazmierczaki (sünd. 1951), Ewa Rybska (sünd. 1958), Artur Grabowski ja Pawel Kwasniewski (sünd. 1963) performance'ite esitlus. Korraldaja Gert Hatsukov

Overcoming family planning challenges in Africa: toward meeting ...

African Journals Online (AJOL)

Overcoming family planning challenges in Africa: toward meeting unmet need and scaling up service delivery. Andrzej Kulczycki. Abstract. No Abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals Online. HOW TO USE AJOL.

Supercomputing - Use Cases, Advances, The Future (1/2)

CERN Multimedia

CERN. Geneva

2017-01-01

Supercomputing has become a staple of science and the poster child for aggressive developments in silicon technology, energy efficiency and programming. In this series we examine the key components of supercomputing setups and the various advances – recent and past – that made headlines and delivered bigger and bigger machines. We also take a closer look at the future prospects of supercomputing, and the extent of its overlap with high throughput computing, in the context of main use cases ranging from oil exploration to market simulation. On the first day, we will focus on the history and theory of supercomputing, the top500 list and the hardware that makes supercomputers tick. Lecturer's short bio: Andrzej Nowak has 10 years of experience in computing technologies, primarily from CERN openlab and Intel. At CERN, he managed a research lab collaborating with Intel and was part of the openlab Chief Technology Office. Andrzej also worked closely and initiated projects with the private sector (e.g. HP an...

The Journey of a Source Line: How your Code is Translated into a Controlled Flow of Electrons

CERN Multimedia

CERN. Geneva

2018-01-01

In this series we help you understand the bits and pieces that make your code command the underlying hardware. A multitude of layers translate and optimize source code, written in compiled and interpreted programming languages such as C++, Python or Java, to machine language. We explain the role and behavior of the layers in question in a typical usage scenario. While our main focus is on compilers and interpreters, we also talk about other facilities - such as the operating system, instruction sets and instruction decoders.   Biographie: Andrzej Nowak runs TIK Services, a technology and innovation consultancy based in Geneva, Switzerland. In the recent past, he co-founded and sold an award-winning Fintech start-up focused on peer-to-peer lending. Earlier, Andrzej worked at Intel and in the CERN openlab. At openlab, he managed a lab collaborating with Intel and was part of the Chief Technology Office, which set up next-generation technology projects for CERN and the openlab partne...

Supercomputing - Use Cases, Advances, The Future (2/2)

CERN Multimedia

CERN. Geneva

2017-01-01

Supercomputing has become a staple of science and the poster child for aggressive developments in silicon technology, energy efficiency and programming. In this series we examine the key components of supercomputing setups and the various advances – recent and past – that made headlines and delivered bigger and bigger machines. We also take a closer look at the future prospects of supercomputing, and the extent of its overlap with high throughput computing, in the context of main use cases ranging from oil exploration to market simulation. On the second day, we will focus on software and software paradigms driving supercomputers, workloads that need supercomputing treatment, advances in technology and possible future developments. Lecturer's short bio: Andrzej Nowak has 10 years of experience in computing technologies, primarily from CERN openlab and Intel. At CERN, he managed a research lab collaborating with Intel and was part of the openlab Chief Technology Office. Andrzej also worked closely and i...

Future Computing Technology (1/3)

CERN Multimedia

CERN. Geneva

2015-01-01

Computing of the future will be affected by a number of fundamental technologies in development today, many of which are already on the way to becoming commercialized. In this series of lectures, we will discuss hardware and software development that will become mainstream in the timeframe of a few years and how they will shape or change the computing landscape - commercial and personal alike. Topics range from processor and memory aspects, programming models and the limits of artificial intelligence, up to end-user interaction with wearables or e-textiles. We discuss the impact of these technologies on the art of programming, the data centres of the future and daily life. Lecturer's short bio: Andrzej Nowak has 10 years of experience in computing technologies, primarily from CERN openlab and Intel. At CERN, he managed a research lab collaborating with Intel and was part of the openlab Chief Technology Office. Andrzej also worked closely and initiated projects with the private sector (e.g. HP and Go...

An Introduction to Parallelism, Concurrency and Acceleration (1/2)

CERN Multimedia

CERN. Geneva

2016-01-01

Concurrency and parallelism are firm elements of any modern computing infrastructure, made even more prominent by the emergence of accelerators. These lectures offer an introduction to these important concepts. We will begin with a brief refresher of recent hardware offerings to modern-day programmers. We will then open the main discussion with an overview of the laws and practical aspects of scalability. Key parallelism data structures, patterns and algorithms will be shown. The main threats to scalability and mitigation strategies will be discussed in the context of real-life optimization problems. Lecturer's short bio: Andrzej Nowak has 10 years of experience in computing technologies, primarily from CERN openlab and Intel. At CERN, he managed a research lab collaborating with Intel and was part of the openlab Chief Technology Office. Andrzej also worked closely and initiated projects with the private sector (e.g. HP and Google), as well as international research institutes, such as EPFL. Current...

The Journey of a Source Line: How your Code is Translated into a Controlled Flow of Electrons

CERN Multimedia

CERN. Geneva

2018-01-01

In this series we help you understand the bits and pieces that make your code command the underlying hardware. A multitude of layers translate and optimize source code, written in compiled and interpreted programming languages such as C++, Python or Java, to machine language. We explain the role and behavior of the layers in question in a typical usage scenario. While our main focus is on compilers and interpreters, we also talk about other facilities - such as the operating system, instruction sets and instruction decoders. Biographie: Andrzej Nowak runs TIK Services, a technology and innovation consultancy based in Geneva, Switzerland. In the recent past, he co-founded and sold an award-winning Fintech start-up focused on peer-to-peer lending. Earlier, Andrzej worked at Intel and in the CERN openlab. At openlab, he managed a lab collaborating with Intel and was part of the Chief Technology Office, which set up next-generation technology projects for CERN and the openlab partners.

Translations on Eastern Europe, Political, sociological, and Military Affairs. Number 1314.

Science.gov (United States)

1976-11-02

8217 as Determinant of Democracy, Patriotism (Andrzej Burda; IDEOLOGIA I POLITYKA, Sep 76) 32 Cardinal Wyszyniski’s Trip to Rome Noted (SLOWO...CSO: 2600 31 POLAND ’STATE CONSCIOUSNESS’ AS DETERMINANT OF DEMOCRACY, PATRIOTISM Warsaw IDEOLOGIA I POLITYKA in Polish No 9, Sep 76 pp 7-15

EWAS: Modeling Application for Early Detection of Terrorist Threats

Science.gov (United States)

Qureshi, Pir Abdul Rasool; Memon, Nasrullah; Wiil, Uffe Kock

This paper presents a model and system architecture for an early warning system to detect terrorist threats. The paper discusses the shortcomings of state-of-the-art systems and outlines the functional requirements that must to be met by an ideal system working in the counterterrorism domain. The concept of generation of early warnings to predict terrorist threats is presented. The model relies on data collection from open data sources, information retrieval, information extraction for preparing structured workable data sets from available unstructured data, and finally detailed investigation. The conducted investigation includes social network analysis, investigative data mining, and heuristic rules for the study of complex covert networks for terrorist threat indication. The presented model and system architecture can be used as a core framework for an early warning system.

Jllumina - A comprehensive Java-based API for statistical Illumina Infinium HumanMethylation450 and Infinium MethylationEPIC BeadChip data processing

Directory of Open Access Journals (Sweden)

Almeida Diogo

2016-10-01

Full Text Available Measuring differential methylation of the DNA is the nowadays most common approach to linking epigenetic modifications to diseases (called epigenome-wide association studies, EWAS. For its low cost, its efficiency and easy handling, the Illumina HumanMethylation450 BeadChip and its successor, the Infinium MethylationEPIC BeadChip, is the by far most popular techniques for conduction EWAS in large patient cohorts. Despite the popularity of this chip technology, raw data processing and statistical analysis of the array data remains far from trivial and still lacks dedicated software libraries enabling high quality and statistically sound downstream analyses. As of yet, only R-based solutions are freely available for low-level processing of the Illumina chip data. However, the lack of alternative libraries poses a hurdle for the development of new bioinformatic tools, in particular when it comes to web services or applications where run time and memory consumption matter, or EWAS data analysis is an integrative part of a bigger framework or data analysis pipeline. We have therefore developed and implemented Jllumina, an open-source Java library for raw data manipulation of Illumina Infinium HumanMethylation450 and Infinium MethylationEPIC BeadChip data, supporting the developer with Java functions covering reading and preprocessing the raw data, down to statistical assessment, permutation tests, and identification of differentially methylated loci. Jllumina is fully parallelizable and publicly available at http://dimmer.compbio.sdu.dk/download.html

Effect of heparan sulfate and gold nanoparticles on muscle development during embryogenesis

Directory of Open Access Journals (Sweden)

Zielinska M

2011-12-01

Full Text Available Marlena Zielinska1,2, Ewa Sawosz1, Marta Grodzik1, Mateusz Wierzbicki1, Maria Gromadka1, Anna Hotowy3, Filip Sawosz3, Andrzej Lozicki1, Andrè Chwalibog31Division of Biotechnology and Biochemistry of Nutrition, Warsaw University of Life sciences, Warsaw, 2The Kielanowski Institute of Animal Physiology and Nutrition, Jablonna, Poland; 3Department of Basic Animal and Veterinary sciences, University of copenhagen, Frederiksberg, DenmarkPurpose: It was hypothesized that heparan sulfate (HS as an essential compound for myogenesis and nanoparticles of gold (nano-Au as highly reactive compounds can affect muscle development as a consequence of molecular regulation of muscle cell formation, and that these effects may be enhanced by a complex of HS conjugated with nano-Au. The objective of the present study was to determine the effect of administration of nano-Au, HS, and a nano-Au+HS complex on the morphological and molecular characteristics of breast muscle during embryogenesis.Methods: Chicken embryos were used as in vivo model. Fertilized chicken eggs (n = 350 were randomly divided into the control group and the groups treated with nano-Au, HS, and nano-Au+HS. The experimental solutions were given in ovo on the first day of incubation and the embryos were evaluated on day 20 of incubation. The methods included biochemical indi- ces in blood, immunohistochemistry, microscopy (transmission electron microscopy, scanning electron microscopy, confocal, and gene expression at the messenger ribonucleic acid and protein levels.Results: The treatments did not adversely affect mortality, organ weight, and homeostasis of the embryos. HS stimulated the development and maturation of breast muscle by increasing the number of nuclei, satellite cells, and muscle fibers and affected the expression of basic fibroblast growth factor-2 and paired-box transcription factor-7. Furthermore, the nano-Au+HS complex contributed to the increased number of myocytes and nuclei in

Kirjad Sirbile / Mart Kivastik

Index Scriptorium Estoniae

Kivastik, Mart, 1963-

2007-01-01

Mannheimi filmifestivalist. Filmidest "Nadine" (rezh. Erik de Bruyn), "Dead End", "Kremen" (rezh. Aleksei Mizgirev), "Overnight" (rezh. Ferenc Török), "Mirush" ("Blodsband", rezh. Marius Holst), "Sztuczki" (rezh. Andrzej Jakimowski), "Por sus propios ojos" ("Through her own eyes", rezh. Liliana Paolinelli), "Terra Sonambula" ("Sleepwalking Land", rezh. Teresa Prata). Festivali auhinnatud filmid

Air pollution: worldwide effects on mountain forests

Science.gov (United States)

Anne M. Rosenthal; Andrzej Featured: Bytnerowicz

2004-01-01

Widespread forest decline in remote areas of the Carpathian Mountains has been linked to air pollution from urban and industrial regions. Besides injuring plant tissues directly, pollutants may deposit to soils and water, drastically changing susceptible ecosystems. Researcher Andrzej Bytnerowicz has developed effective methods for assessing air quality over wildlands...

A Cellular Automata Approach to Computer Vision and Image Processing.

Science.gov (United States)

1980-09-01

the ACM, vol. 15, no. 9, pp. 827-837. [ Duda and Hart] R. 0. Duda and P. E. Hart, Pattern Classification and Scene Analysis, Wiley, New York, 1973...Center TR-738, 1979. [Farley] Arthur M. Farley and Andrzej Proskurowski, "Gossiping in Grid Graphs", University of Oregon Computer Science Department CS-TR

Paweł Bąk, Die Metapher in der Übersetzung. Studien zum Transfer der Aphorismen von Stanisław Jerzy Lec und der Gedichte von Wisława Szymborska, Peter Lang Europäischer Verlag der Wissenschaft en, Frankfurt am Main u. a. 2007 =...

OpenAIRE

Zieliński, Lech

2008-01-01

Paweł Bąk, Die Metapher in der Ubersetzung. Studien zum Transfer der Aphorismen von Stanisław Jerzy Lec und der Gedichte von Wisława Szymborska, Peter Lang Europaischer Verlag der Wissenschaft en, Frankfurt am Main u. a. 2007 = Danziger Beitrage zur Germanistik, Bd. 20 wyd. Andrzej Kątny, 332 strony

Biomarkers of exposure in environment-wide association studies - Opportunities to decode the exposome using human biomonitoring data.

Science.gov (United States)

Steckling, Nadine; Gotti, Alberto; Bose-O'Reilly, Stephan; Chapizanis, Dimitris; Costopoulou, Danae; De Vocht, Frank; Garí, Mercè; Grimalt, Joan O; Heath, Ester; Hiscock, Rosemary; Jagodic, Marta; Karakitsios, Spyros P; Kedikoglou, Kleopatra; Kosjek, Tina; Leondiadis, Leondios; Maggos, Thomas; Mazej, Darja; Polańska, Kinga; Povey, Andrew; Rovira, Joaquim; Schoierer, Julia; Schuhmacher, Marta; Špirić, Zdravko; Stajnko, Anja; Stierum, Rob; Tratnik, Janja Snoj; Vassiliadou, Irene; Annesi-Maesano, Isabella; Horvat, Milena; Sarigiannis, Dimosthenis A

2018-07-01

The European Union's 7th Framework Programme (EU's FP7) project HEALS - Health and Environment-wide Associations based on Large Population Surveys - aims a refinement of the methodology to elucidate the human exposome. Human biomonitoring (HBM) provides a valuable tool for understanding the magnitude of human exposure from all pathways and sources. However, availability of specific biomarkers of exposure (BoE) is limited. The objective was to summarize the availability of BoEs for a broad range of environmental stressors and exposure determinants and corresponding reference and exposure limit values and biomonitoring equivalents useful for unraveling the exposome using the framework of environment-wide association studies (EWAS). In a face-to-face group discussion, scope, content, and structure of the HEALS deliverable "Guidelines for appropriate BoE selection for EWAS studies" were determined. An expert-driven, distributed, narrative review process involving around 30 individuals of the HEALS consortium made it possible to include extensive information targeted towards the specific characteristics of various environmental stressors and exposure determinants. From the resulting 265 page report, targeted information about BoE, corresponding reference values (e.g., 95th percentile or measures of central tendency), exposure limit values (e.g., the German HBM I and II values) and biomonitoring equivalents (BEs) were summarized and updated. 64 individual biological, chemical, physical, psychological and social environmental stressors or exposure determinants were included to fulfil the requirements of EWAS. The list of available BoEs is extensive with a number of 135; however, 12 of the stressors and exposure determinants considered do not leave any measurable specific substance in accessible body specimens. Opportunities to estimate the internal exposure stressors not (yet) detectable in human specimens were discussed. Data about internal exposures are useful to decode

On the potential of models for location and scale for genome-wide DNA methylation data.

Science.gov (United States)

Wahl, Simone; Fenske, Nora; Zeilinger, Sonja; Suhre, Karsten; Gieger, Christian; Waldenberger, Melanie; Grallert, Harald; Schmid, Matthias

2014-07-03

With the help of epigenome-wide association studies (EWAS), increasing knowledge on the role of epigenetic mechanisms such as DNA methylation in disease processes is obtained. In addition, EWAS aid the understanding of behavioral and environmental effects on DNA methylation. In terms of statistical analysis, specific challenges arise from the characteristics of methylation data. First, methylation β-values represent proportions with skewed and heteroscedastic distributions. Thus, traditional modeling strategies assuming a normally distributed response might not be appropriate. Second, recent evidence suggests that not only mean differences but also variability in site-specific DNA methylation associates with diseases, including cancer. The purpose of this study was to compare different modeling strategies for methylation data in terms of model performance and performance of downstream hypothesis tests. Specifically, we used the generalized additive models for location, scale and shape (GAMLSS) framework to compare beta regression with Gaussian regression on raw, binary logit and arcsine square root transformed methylation data, with and without modeling a covariate effect on the scale parameter. Using simulated and real data from a large population-based study and an independent sample of cancer patients and healthy controls, we show that beta regression does not outperform competing strategies in terms of model performance. In addition, Gaussian models for location and scale showed an improved performance as compared to models for location only. The best performance was observed for the Gaussian model on binary logit transformed β-values, referred to as M-values. Our results further suggest that models for location and scale are specifically sensitive towards violations of the distribution assumption and towards outliers in the methylation data. Therefore, a resampling procedure is proposed as a mode of inference and shown to diminish type I error rate in

An epigenome-wide study of obesity in African American youth and young adults : novel findings, replication in neutrophils, and relationship with gene expression

NARCIS (Netherlands)

Wang, Xiaoling; Pan, Yue; Zhu, Haidong; Hao, Guang; Huang, Yisong; Barnes, Vernon; Shi, Huidong; Snieder, Harold; Pankow, James; North, Kari; Grove, Megan; Guan, Weihua; Demerath, Ellen; Dong, Yanbin; Su, Shaoyong

2018-01-01

Background: We conducted an epigenome-wide association study (EWAS) on obesity in healthy youth and young adults and further examined to what extent identified signals influenced gene expression and were independent of cell type composition and obesity-related cardio-metabolic risk factors.

Poolakad eesti kunsti omaruumis / Riin Kübarsepp

Index Scriptorium Estoniae

Kübarsepp, Riin, 1978-

2004-01-01

Vaal-galeriis 29. V toimunud poola tegevuskunsti pärastlõunast "Tramsmission" ja osalenud kunstnikest (Dariusz Fodczuki, Wladislaw Kazmierczak, Ewa Rybska, Pawel Kwasniewski). Tähenduslikuna mõjus galeriis väljas olnud Jüri Ojaveri ruumiinstallatsioon "...töökas ning leidlik"

Ergonomic work analysis: A case study of bus drivers in the private collective transportation sector.

Science.gov (United States)

Araújo, Adolfo Vicente; Arcanjo, Gemima Santos; Fernandes, Haroldo; Arcanjo, Georgia Santos

2018-05-03

The collective transportation system is essential to reduce the number of automobiles in the roads. Concerns exist related to quality, comfort and safety of bus driver's workstations. The objective of this study was to improve the driver's workstation in the private collective transportation sector by analyzing ergonomic practices using the Ergonomic Work Analysis (EWA). The EWA was chosen because it seeks to evaluate the labor condition as it relates to the psychophysiological conditions of workers, it complies with regulatory standard 17 (NR17). To identify driver concerns, interviews and questionnaires were administered. The workstation and worker routines were observed. The analysis revealed that the largest number of complaints related to noise, display light and location of the passenger identifier device. Drivers reported discomfort in the knees and lower back. Recommendations were made to improve the workstation and change the routine to minimize the discomfort and ergonomic risk factors.

Effect of Nuclear Reactions on the Properties of Al-Mg-Si Alloys after Long-Time Exploitation in Research Reactors

CERN Document Server

Hofmann, A; Szteke, W; Hajewska, E; Wagner, T; Semina, V K

2004-01-01

Effect of fast neutron ($E>$ 0.1~?eV) irradiation on the mechanical properties and fracture morphology of the Al-Mg-Si alloys (PAR-1 and ???-1) after 40 years of exploitation in research nuclear reactors has been studied. Tested specimens were cut from structural elements of reactor EWA ($\\acute{\\rm S}$wierk, Poland). Irradiation induces degradation in mechanical properties, namely yield strength and ultimate strength increase, but elongation reduces. The mechanical property changes are caused by ageing of Al--Mg--Si alloy. During irradiation Si is formed from Al by the Al($n, \\gamma $)Si reaction. The presence of Si might cause strengthening of the Al--Mg--Si alloys by increasing precipitation of Mg$_{2}$Si or pure Si in the Al matrix. Post-irradiation activity studies of EWA reactor structural elements show that the high-activity $^{60}$Co and $^{65}$Zn isotopes have been formed by the nuclear reactions.

Effect of nuclear reactions on the properties of Al-Mg-Si alloys after long-time exploitation in research reactors

International Nuclear Information System (INIS)

Hofman, A.; Didyk, A.Yu.; Semina, V.K.; Szteke, W.; Hajewska, E.; Wagner, T.

2004-01-01

Effect of fast neutron (E > 0.1 MeV) irradiation on the mechanical properties and fracture morphology of the Al-Mg-Si alloys (PAR-1 and CAB-1) after 40 years of exploitation in research nuclear reactors has been studied. Tested specimens were cut from structural elements of reactor EWA (Swierk, Poland). Irradiation induces degradation in mechanical properties, namely yield strength and ultimate strength increase, but elongation reduces. The mechanical property changes are caused by ageing of Al-Mg-Si alloys. During irradiation Si is formed from Al by the Al(n, γ)Si reaction. The presence of Si might cause strengthening of the Al-Mg-Si alloys by increasing precipitation of Mg 2 Si or pure Si in the Al matrix. Post-irradiation activity studies of EWA reactor structural elements show that the high-activity 60 Co and 65 Zn isotopes have been formed by the nuclear reactions

LINAC4 takes a tour of Europe

CERN Multimedia

Katarina Anthony

2011-01-01

Along the German Autobahnen, a truck carrying 20 tonnes of copper is on its way to Poland. The metal has already made a short tour of Europe, yet the drive across the high-speed highway is only the beginning of its transformation into CERN’s next linear accelerator, LINAC4.   Grzegorz Wrochna (left), director of the Andrzej Soltan Institute for Nuclear Studies (IPJ), and Rolf Heuer (right), CERN DG, sign the framework agreement between the two institutes. By the summer of 2012, the PI-Mode Structures (PIMS) will be constructed and completely installed in the LINAC4 tunnel. The PIMS cavities are the final accelerating structures needed for LINAC4, and have been designed to accelerate protons from 100 to 160MeV. While the first cavity was built entirely at CERN, construction of the remaining cavities has become a larger, multi-national operation. In a 1 million euro framework agreement signed on 11 February by the Director-General, the Andrzej Soltan Institute for Nuclear Studies in Swie...

Classes evaluation: Methods and tools

Directory of Open Access Journals (Sweden)

Grabiński Tadeusz

2013-01-01

Full Text Available This study presents a method, tools, course and results of foreign language classes evaluation conducted in the summer semester 2012/2013 in the Andrzej Frycz - Modrzewski Krakow University. Because a new evaluation procedure has been implemented at the University, the former method - based on paper forms filled in by the students - was abandoned. On the surveyanyplace.com website, a free account has been registered and the form of the evaluation questionnaire has been inserted. This coverage presents results of a taxometric analysis aimed at checking the degree of mutual correspondence (correlation between certain criteria and instancing a graphic presentation of the evaluation results in a multidimensional perspective. In order to classify the grading criteria, the Ward's agglomerative method, along with Euclidean metric as a measure of criteria similarity, have been used. Calculations have been made with the use of Statistica package. Results of the questionnaire show that foreign language teaching at the Andrzej Frycz Modrzewski Krakow University is conducted professionally and on a high factual level.

Postsotsialistlik Eesti filmikunst kui rahvusülene kino / Ewa Mazierska

Index Scriptorium Estoniae

Mazierska, Ewa

2011-01-01

Käsitletakse Nõukogude Liidu lagunemise järel valminud Eesti filme, võrreldes neid mujal ja teisel ajal loodud linateostega. Võrdluse tulemusena selgub, et Eesti film on pidevas dialoogis Euroopa ja maailma kinoga, ent suudab rääkida ka oma häälega, et ta on nii rahvuslik kui ka rahvusülene nähtus, suutes ka ise midagi teistele pakkuda

Tegn. Red.

African Journals Online (AJOL)

rbr

gawe uit meer as twee maal soveel lemmas sal bestaan. Selfs tien duisend lem- mas sal geensins 'n volledige versameling "etimologiseerbare" Afrikaanse lemmas verteenwoordig nie, en dit is goed dat EWA geensins makrostruktu- rele volledigheid op die agenda het nie. Nogtans, hoewel daar in hierdie stadium niks oor ...

Summary of Session 4 'Strategy for 2012 (II)'

International Nuclear Information System (INIS)

Bruning, Oliver; Ponce, Laurette

2012-01-01

The fourth session of the 2012 LHC Performance Workshop included the following presentations: • Beam Energy by Andrzej Siemko; • Optics Options by Massimo Giovannozzi; • Collimation settings and performance by Roderik Bruce; • Performance Reach in the LHC for 2012 by Gianluigi Arduini; • MD plans in 2012 by Ralph Wolfgang Assmann; • Ions in 2012 by John Jowett

Annual Report 2008

Energy Technology Data Exchange (ETDEWEB)

Keeley, N; Skalski, J [The Andrzej Soltan Institute for Nuclear Studies, Swierk-Otwock (Poland)

2009-07-01

The ''Annual Report 2008'' describes activities of Andrzej Soltan Institute for Nuclear Studies in 2008. Report consists of two parts. First one consists of general information about location, management, scientific council, personnel, financial support and conferences while the second one describes the scientific activity of Institute. A Foreword to all report written by Director of the Institute prof. Grzegorz Wrochna is also given.

Summary of Session 4 'Strategy for 2012 (II)'

Energy Technology Data Exchange (ETDEWEB)

Bruning, Oliver; Ponce, Laurette [European Organization for Nuclear Research, Geneva (Switzerland)

2012-07-01

The fourth session of the 2012 LHC Performance Workshop included the following presentations: • Beam Energy by Andrzej Siemko; • Optics Options by Massimo Giovannozzi; • Collimation settings and performance by Roderik Bruce; • Performance Reach in the LHC for 2012 by Gianluigi Arduini; • MD plans in 2012 by Ralph Wolfgang Assmann; • Ions in 2012 by John Jowett.

Annual Report 2008

International Nuclear Information System (INIS)

Keeley, N.; Skalski, J.

2009-01-01

The ''Annual Report 2008'' describes activities of Andrzej Soltan Institute for Nuclear Studies in 2008. Report consists of two parts. First one consists of general information about location, management, scientific council, personnel, financial support and conferences while the second one describes the scientific activity of Institute. A Foreword to all report written by Director of the Institute prof. Grzegorz Wrochna is also given

West African Journal of Applied Ecology - Vol 9, No 1 (2006)

African Journals Online (AJOL)

Ecological effects of channelization on a tropical marine ecosystem: Impact on intertidal fish communities in the Cross River, Nigeria · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. IO Ewa-Oboho. http://dx.doi.org/10.4314/wajae.v9i1.45674 ...

The reminiscence of the doctoral seminar of the Nicolaus Copernicus University Archive Studies Department from 1966 to 1974

Directory of Open Access Journals (Sweden)

Bohdan Ryszewski

2015-03-01

Full Text Available Andrzej Tomczak began creating a doctoral seminar in 1965 and he invited Zygmunt Kolankowski, who had been the director of the Archive of the Polish Academy of Sciences (PAN. A little later, Irena Jarosz – Biskup was also invited to contribute to it. Both the alumni of the Torun Archive Studies Department, and the active employees of the Warsaw archives, took part in these seminars. The meetings had been held regularly, and the participants’ presentations had served as an opportunity for an animated debate on the subject of the archive-related problems. The seminar’s participants were inter alia: Olimpia Staron, Weronika Klonowska, Aniela Przywuska, Bohdan Ryszewski, Zdzislaw Chmielewski, Mieczyslaw Stelmach, Halina Robotka, Roman Marchwinski. The seminar led by Andrzej Tomczak was terminated at the beginning of the 1980s. Eleven degrees had been obtained in the course of the aforementioned seminar. (A. Tomczak conferred 8 PhD degrees; Z. Kolankowski – 2; I. Janosz-Biskupowa – 1 Five of the Tomczak’s doctoral degree recipients, later obtained professorships, three from among those received the titles from the President of Poland. His students’ seminars have, in turn, assisted in producing the next generation’s doctors.

Powieść reportażowa czy dziennikarska? Uwagi o międzywojennej twórczości prozatorskiej Jalu Kurka

OpenAIRE

Adamczewska, Izabella

2015-01-01

The paper focuses on genealogical aspects of three interwar novels by Jalu Kurek – Andrzej Panik, Grypa szaleje w Naprawie, Woda wyżej) – which have often been described by critics as “reportage novels”. The author examines the past critical reception of the novels and the intentio auctioris. The main goal of the article is to suggest a more capacious genealogical term: the journalistic novel.

Powieść reportażowa czy dziennikarska?Uwagi o międzywojennej twórczości prozatorskiej Jalu Kurka

OpenAIRE

Adamczewska, Izabella

2015-01-01

International audience; The paper focuses on genealogical aspects of three interwar novels by Jalu Kurek – AndrzejPanik, Grypa szaleje w Naprawie, Woda wyżej) – which have often been described by critics as“reportage novels”. The author examines the past critical reception of the novels and the intentioauctioris. The main goal of the article is to suggest a more capacious genealogical term: the journalisticnovel.

A Non-Cognitive Formal Approach to Knowledge Representation in Artificial Intelligence.

Science.gov (United States)

1986-06-01

example, Duda and others translated production rules into a partitioned semantic network (73). Representations were also translated into production...153. Berlin: Springer-Verlag, 1982. 38. Blikle, Andrzej . "Equational Languages," Information and Control, 21: 134-147 (September 1972). 285 39. Ezawa...Conference on Artificial Intelligence, IJCAI-75. 115-121. William Kaufmann, Inc., Los Altos CA, 1975. 73. Duda , Richard 0. and others. "Semantic

What's Wrong with Copyright: Educator Strategies for Dealing with Analog Copyright Law in a Digital World

Science.gov (United States)

McGrail, J. Patrick; McGrail, Ewa

2009-01-01

Current copyright law was formulated before the digital technology became widely available and well before Web 2.0 changed the way that information is created and shared. J. Patrick McGrail and Ewa McGrail argue that copyright law has failed to keep up with the social and legal changes that have accompanied the technological developments of the…

Graph Structure Theory: Proceedings of a Joint Summer Research Conference on Graph Minors Held June 22 to July 5, 1991, at the University of Washington, Seattle. Contemporary Mathematics 147

Science.gov (United States)

1991-01-01

Rudolf Miiller, A combinatorial approach to obtain bounds for stochastic project neworka, Tech. report, Technische Universitit Berlin, 1991. [Pou851 M...appear). 600 ANDRZEJ PROSKUROWSKI [201 J.A. Wald and C.J. Colbourn, Steiner trees, partial 2-trees, and minimum IFI networks, Networks 13 (1983), 159-167...Colbourn, Steiner trees, partial 2-trees and minimum IFI networks, Networks 13, (1983), 159-167. DEPARTMENT OF COMPUTER SCIENCE, UNIVERSITY OF

Uranium in mining water of kaolin open pit in Zarów (Lower Silesia); methodology of determination and genetic remarks.

Science.gov (United States)

Chau, N D; Wyszomirski, P; Chruściel, E; Ochoński, A

1999-11-01

In this paper, a method of determination of uranium 238 and 234 in mining waters of Andrzej kaolin open pit in Zarów (Lower Silesia) is presented. The method is based on independent measurements of alpha and beta radiation intensities by means of a liquid scintillation spectrometer alpha/beta. The initial volume of water sample was 3 dm3, then it was diminished by chemical preparation to 6 cm3, and then 12 cm3 of scintillator was added. The lower limit of detection (for the measurement time of 8 h) for both 234U and 238U amounted to 0.02 Bq/dm3. For determination of the uranium content in ferruginous sediments precipitating from mining waters of the above-mentioned open pit, gamma ray spectrometry was used. The obtained results may be viewed as a contribution to studies on anomalous uranium concentration within this kaolin deposit. The elevated uranium content, in comparison with its average concentration in the Earth crust, is characteristic for parent rocks of Andrzej kaolin deposit, which are granitoids of Strzegom-Sobótka massif. In connection with it, the high uranium content can be observed not only in kaolin and weakly kaolinised granitoids from the deposit in question, but also in mining waters genetically related with them.

Rodzina imigrancka z perspektywy historycznej: doświadczenia polskich pionierów w Winnipeg, 1896-1919

OpenAIRE

ALBAŃSKI, ŁUKASZ

2011-01-01

This paper focuses on an early Polish family life in Winnipeg. The family often served as a mechanism to reduce a sense of dislocation and to facilitate immigrants' adaptation. The family was also the primary economic unit. The family relations were affected by gender. Both immigrant men and women found themselves reconsidering traditional roles. Somehow immigration tested their family roles in newways. Ewa Jurczyk-Romanowska

Annual Report 2006

International Nuclear Information System (INIS)

Chmielewska, D.; Infeld, E.; Zupranski, P.

2007-06-01

The ''Annual Report 2006'' describes activities of Andrzej Soltan Institute for Nuclear Studies in 2006. Report consists in general two parts. First consists of general information about location, management, scientific council, personnel, financial support and conferences while the second one the scientific activity of Institute. This part is divided into subsections which present progress in research of the Institut Departments and Establishments. A Foreword to report written by Director of the Institute Grzegorz Wrochna is also given

Annual Report 2006

Energy Technology Data Exchange (ETDEWEB)

Chmielewska, D; Infeld, E; Zupranski, P [The Andrzej Soltan Institute for Nuclear Studies, Swierk-Otwock (Poland)

2007-06-15

The ''Annual Report 2006'' describes activities of Andrzej Soltan Institute for Nuclear Studies in 2006. Report consists in general two parts. First consists of general information about location, management, scientific council, personnel, financial support and conferences while the second one the scientific activity of Institute. This part is divided into subsections which present progress in research of the Institut Departments and Establishments. A Foreword to report written by Director of the Institute Grzegorz Wrochna is also given.

Studia nad strukturą przestrzenno-funkcjonalną miasta. Przykład Brodnica

OpenAIRE

Matczak, Andrzej; Szymańska, Daniela

1997-01-01

contribution: Szymańska Daniela - 50 % Marczak Andrzej - 50% Summary. A market economy has been restored to Poland since 1989. It is expected that it will liberate local socio-economic initiatives. Small towns will gradually regain market grounds for existence through imparting dynamism to the growth of the operation of servicing the surrounding area. At present, it seems that a particularly advantageous starting position has been gained by those small towns which, after world war I...

Annual Report 2005

Energy Technology Data Exchange (ETDEWEB)

Chmielewska, D; Infeld, E; Zupranski, P [The Andrzej Soltan Institute for Nuclear Studies, Swierk-Otwock (Poland)

2006-06-15

The ''Annual Report 2005'' describes activities of Andrzej Soltan Institute for Nuclear Studies in 2005. Report consists in general two parts. First consists of general information about location, management, scientific council, personnel financial support and conferences while the second one the scientific activity of Institute. This part is divided into subsections which present progress in research of the Institut Departments and Establishments. A Foreword to report written by Director of the Institute prof. Ziemowit Sujkowski is also given.

Annual Report 2005

International Nuclear Information System (INIS)

Chmielewska, D.; Infeld, E.; Zupranski, P.

2006-06-01

The ''Annual Report 2005'' describes activities of Andrzej Soltan Institute for Nuclear Studies in 2005. Report consists in general two parts. First consists of general information about location, management, scientific council, personnel financial support and conferences while the second one the scientific activity of Institute. This part is divided into subsections which present progress in research of the Institut Departments and Establishments. A Foreword to report written by Director of the Institute prof. Ziemowit Sujkowski is also given

A control and recording system for a neutron diffractometer

International Nuclear Information System (INIS)

Czech, Z.; Turek, L.; Wierzewski, K.

1982-01-01

A digital system for automatic control and data recording being a part of a neutron diffractometer designed for measurement of the angular distribution of monochromatic neutrons is described. The system is built using digital TTL integrated circuits. Particular attention is drawn to the interesting design of the optimized cross-matrix which selects the elements subjected to recording. The system successfully works with the neutron diffractometer at the EWA reactor. (author)

Radiation waste management in Poland; Unieszkodliwianie odpadow promieniotworczych w Polsce

Energy Technology Data Exchange (ETDEWEB)

Tomczak, W. [Institute of Atomic Energy, Otwock-Swierk (Poland)

1995-12-31

Radioactive waste management especially related to storage of spent fuel from Ewa and Maria research nuclear reactors has been presented. The classification and balance of radioactive wastes coming from different branches of nuclear activities have been shown. The methods of their treatment in respect of physical state and radioactive have been performed as well as their storage in Central Polish Repository have been introduced. 2 figs, 4 tabs.

Radiation waste management in Poland

International Nuclear Information System (INIS)

Tomczak, W.

1995-01-01

Radioactive waste management especially related to storage of spent fuel from Ewa and Maria research nuclear reactors has been presented. The classification and balance of radioactive wastes coming from different branches of nuclear activities have been shown. The methods of their treatment in respect of physical state and radioactive have been performed as well as their storage in Central Polish Repository have been introduced. 2 figs, 4 tabs

Archaeological and Paleontological Salvage at Barbers Point, Oahu

Science.gov (United States)

1978-03-01

Ewa Plain, a former coral-algae calcareous reef that emerged following the post-Pleistocene sea-level subsidence. The topography that usually results...endangered floral species are present in this area, as well as several other rare and uncommon plants . No endangered species of fauna are recorded from...larger pits was used for cultivation and even today one comes upon bananas and Hawaiian sugarcane still growing in them [McAllister 1933:1091

Wybrane błędy językowe na przykładzie analizy funkcjonowania Poradni Językowej PWN

Directory of Open Access Journals (Sweden)

Katarzyna Ostrowska

2016-03-01

Full Text Available The article presents the theme of linguistic counseling and online guidance on the basis of Poradnia Językowa PWN. The primary aim of this essay is presenting problematic issues for contemporary Polish (wrong meanings of words: not in the least and at least, technique and technology, reliable, showing expert’s opinions and dictionary analysis (on the basis of Słownik języka polskiego edited by Witold Doroszewski and Wielki słownik poprawnej polszczyzny PWN edited by Andrzej Markowski.

VIP visit to CERN P5 CMS of Pakistan Science Members

CERN Multimedia

Hoch, Michael

2012-01-01

VIP visit to CERN P5 CMS of PAEC & JCPC Science Members List of PAEC Visitors: Dr. Badar Suleman - Member Science PAEC & Member of JCPC Dr. Waqar M. Butt - Member Engineering (Head of HMC3) Dr. Maqsood Ahmad - Chief Scientist (Head of Accelerator Project) List of CMS participants: Prof. Joseph Incandela, CMS Spokesperson Dr. Austin Ball, CMS Technical Coordinator Mr Andrzej Charkiewicz, CMS Resources Manager Dr. Michael Hoch, CMS Outreach activities, CMS photographer and guide Dr. Achille Petrilli, CMS Team Leader

Annual Report 2007

Energy Technology Data Exchange (ETDEWEB)

Chmielewska, D; Infeld, E; Zupranski, P [The Andrzej Soltan Institute for Nuclear Studies, Swierk-Otwock (Poland)

2008-07-01

The ''Annual Report 2007'' describes activities of Andrzej Soltan Institute for Nuclear Studies in 2007. Report consists of two parts. First one consist of of general information about location, management, scientific council, personnel, financial support and conferences while the second one describes the scientific activity of Institute. This part is divided into subsections which present progress in research of the Institut Departments and Establishments. A Foreword to all report written by Director of the Institute prof. Grzegorz Wrochna is also given.

Annual Report 2007

International Nuclear Information System (INIS)

Chmielewska, D.; Infeld, E.; Zupranski, P.

2008-01-01

The ''Annual Report 2007'' describes activities of Andrzej Soltan Institute for Nuclear Studies in 2007. Report consists of two parts. First one consist of of general information about location, management, scientific council, personnel, financial support and conferences while the second one describes the scientific activity of Institute. This part is divided into subsections which present progress in research of the Institut Departments and Establishments. A Foreword to all report written by Director of the Institute prof. Grzegorz Wrochna is also given

Long range personalized cancer treatment strategies incorporating evolutionary dynamics.

Science.gov (United States)

Yeang, Chen-Hsiang; Beckman, Robert A

2016-10-22

approaches, by far the majority show an advantage of multi-step or ALTO over single-step optimization. ALTO-SMO delivers cure rates superior or equal to those of single- or multi-step optimization, in 2 and 3 drug cases respectively. In selected virtual patients incurable by dynamic precision medicine using single-step optimization, analogous strategies that "think ahead" can deliver long-term survival and cure without any disadvantage for non-responders. When therapies require dose reduction in combination (due to toxicity), optimal strategies feature complex patterns involving rapidly interleaved pulses of combinations and high dose monotherapy. This article was reviewed by Wendy Cornell, Marek Kimmel, and Andrzej Swierniak. Wendy Cornell and Andrzej Swierniak are external reviewers (not members of the Biology Direct editorial board). Andrzej Swierniak was nominated by Marek Kimmel.

Wywiad z Ewą Gąsowską

Directory of Open Access Journals (Sweden)

Monika Stec

2014-06-01

Full Text Available An interview with Ewa Gąsowska In the interview, Ewa Gąsowska described her ten-year-long struggle with the Polish legal system. Gąsowska’s objective has been to reinstate the good name of her grandfather, Jan Rybak, who was murdered in 1945. According to Gąsowska, the reason for her grandfather’s death was his political activity in PPR (Polish Labourers’ Party and his post-war commitment to the reconstruction of People’s Poland (Polska Rzeczpospolita Ludowa. Gąsowska claims that he was murdered by members of Narodowe Siły Zbrojne (National Armed Forces. Almost 60 years after the death of Jan Rybak, a book was published which presents his activity and death in a different light. The book had been written by one of those regarded by Rybak’s family as his murderers. This “courtroom drama” is situated in the context of the relations between the Rybak family and the local community (the place where Jan Rybak, and most likely also his murderers, were born, as well as the socio-political transformations in the contemporary Poland.   Wywiad z Ewą Gąsowską Ewa Gąsowska opowiada historię swoich dziesięcioletnich zmagań z wymiarem sprawiedliwości. Jej celem jest rehabilitacja dobrego imienia dziadka, Jana Rybaka, który został zamordowany w 1945 roku. Zdaniem Ewy Gąsowskiej, powodem zabójstwa była partyjna aktywność jej dziadka (PPR i jego powojenne zaangażowanie w odbudowę Polski Ludowej, a jego mordercami byli członkowie Narodowych Sił Zbrojnych. Prawie 60 lat później ukazała się książka wspomnieniowa, która inaczej przedstawia działalność i okoliczności śmierci Jana Rybaka. Jej autorem jest osoba, którą rodzina uważa za mordercę. Ważny kontekst tego „serialu sądowego” stanowią relacje rodziny Rybaka z lokalną społecznością, z której się wywodzi on i – prawdopodobnie – jego zabójcy, jak też przemiany społeczno-polityczne we współczesnej Polsce.

Heat transfer enhancement with nanofluids

CERN Document Server

Bianco, Vincenzo; Nardini, Sergio; Vafai, Kambiz

2015-01-01

Properties of NanofluidSamuel Paolucci and Gianluca PolitiExact Solutions and Their Implications in Anomalous Heat TransferWenhao Li, Chen Yang and Akira NakayamaMechanisms and Models of Thermal Conductivity in NanofluidsSeung-Hyun Lee and Seok Pil JangExperimental Methods for the Characterization of Thermophysical Properties of NanofluidsSergio Bobbo and Laura FedeleNanofluid Forced ConvectionGilles RoyExperimental Study of Convective Heat Transfer in NanofluidsEhsan B. Haghighi, Adi T. Utomo, Andrzej W. Pacek and Björn E. PalmPerformance of Heat Exchangers Using NanofluidsBengt Sundén and Za

Pracoholizm w kategoriach deprecjacji pracy pielęgniarki. Wybrane aspekty = Workaholism in categories of nurses’ work depreciation. Chosen aspects

OpenAIRE

Stychno, Ewa; Kulczycka, Kinga

2016-01-01

Stychno Ewa, Kulczycka Kinga. Pracoholizm w kategoriach deprecjacji pracy pielęgniarki. Wybrane aspekty = Workaholism in categories of nurses’ work depreciation. Chosen aspects. Journal of Education, Health and Sport. 2016;6(10):11-21. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.159507 http://ojs.ukw.edu.pl/index.php/johs/article/view/3920 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12....

Impacts of Freshwater Impoundment in the West Loch of Pearl Harbor

Science.gov (United States)

1993-05-01

absence of applicable non-point standards, the "Yellow Book" criteria for freshwater aquatic life or domestic water supply could be applied to evaluate the...Waimalu, Waipahu, Wahiawa, and Ewa water use districts and contains the largest groundwater body on Oahu, supplying more than 50 percent of the island’s...irrigation; desalt existing brackish water supplies, and; 3 create a freshwater impoundment in West Loch. 6I I I The Board of Water Supply (BWS) and

ESI-HI65 Ewa, Island of Oahu, Hawaii 2001 (Environmental Sensitivity Index Map)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Environmental Sensitivity Index (ESI) maps are an integral component in oil-spill contingency planning and assessment. They serve as a source of information in the...

Physical and psychosocial indicators among office workers from public sector with and without musculoskeletal symptoms.

Science.gov (United States)

Barbieri, Dechristian França; Nogueira, Helen Cristina; Bergamin, Letícia Januário; Oliveira, Ana Beatriz

2012-01-01

Work-related musculoskeletal disorders (WRMD) are the result of the combination of different risk factors. They are very common among computer workers, mainly when neck and upper limbs are considered. Forty-two office workers from a public university participated in this study. They were divided into two groups: Symptomatic Subjects (SS, n=20) and Asymptomatic Subjects (AS, n=22), according to the Nordic Musculoskeletal Questionnaire (NMQ). Psychosocial indicators were assessed using the Job Content Questionnaire (JCQ) and Utrecht Work Engagement Scale (UWES). Workplaces were evaluated according to the Ergonomic Workplace Analysis (EWA), proposed by the Finnish Institute of Occupational Health. The NMQ showed higher weekly prevalence of complaints on neck, shoulders and wrist/hands (p=0.00) among SS. The annual prevalence of symptoms on wrist/hands was also higher among SS (p=0.02). The JCQ did not show any difference between groups (p>0.05). Higher proportion of servers with 'high level' of engagement, dedication and absorption, according to UWES, was identified among SS (p<0.01). EWA showed worse scores for 'Work Site', 'Job Content' and 'Repetitiveness of the Work' among SS (p<0.05). Servers are exposed to physical and psychosocial risk factors that can contribute to the development of WRMD. Work conditions need to be change in order to improve musculoskeletal health.

NEpiC: a network-assisted algorithm for epigenetic studies using mean and variance combined signals.

Science.gov (United States)

Ruan, Peifeng; Shen, Jing; Santella, Regina M; Zhou, Shuigeng; Wang, Shuang

2016-09-19

DNA methylation plays an important role in many biological processes. Existing epigenome-wide association studies (EWAS) have successfully identified aberrantly methylated genes in many diseases and disorders with most studies focusing on analysing methylation sites one at a time. Incorporating prior biological information such as biological networks has been proven to be powerful in identifying disease-associated genes in both gene expression studies and genome-wide association studies (GWAS) but has been under studied in EWAS. Although recent studies have noticed that there are differences in methylation variation in different groups, only a few existing methods consider variance signals in DNA methylation studies. Here, we present a network-assisted algorithm, NEpiC, that combines both mean and variance signals in searching for differentially methylated sub-networks using the protein-protein interaction (PPI) network. In simulation studies, we demonstrate the power gain from using both the prior biological information and variance signals compared to using either of the two or neither information. Applications to several DNA methylation datasets from the Cancer Genome Atlas (TCGA) project and DNA methylation data on hepatocellular carcinoma (HCC) from the Columbia University Medical Center (CUMC) suggest that the proposed NEpiC algorithm identifies more cancer-related genes and generates better replication results. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

Knowledge level and incidence of complications in diabetic patients

OpenAIRE

Krzyżanowska, Ewa; Indycka, Ewelina; Łuczyk, Robert Jan; Łuczyk, Marta; Sawicka, Katarzyna; Wawryniuk, Agnieszka; Daniluk, Jadwiga

2017-01-01

Krzyżanowska Ewa, Indycka Ewelina, Łuczyk Robert Jan, Łuczyk Marta, Sawicka Katarzyna, Wawryniuk Agnieszka, Daniluk Jadwiga. Knowledge level and incidence of complications in diabetic patients. Journal of Education, Health and Sport. 2017;7(8):446-472. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.883767 http://ojs.ukw.edu.pl/index.php/johs/article/view/4758 https://pbn.nauka.gov.pl/sedno-webapp/works/830341 The journal has had 7 points in Min...

Pracoholizm w kategoriach deprecjacji pracy pielęgniarki. Wybrane aspekty = Workaholism in categories of nurses’ work depreciation. Chosen aspects

OpenAIRE

Ewa Stychno; Kinga Kulczycka

2016-01-01

Stychno Ewa, Kulczycka Kinga. Pracoholizm w kategoriach deprecjacji pracy pielęgniarki. Wybrane aspekty = Workaholism in categories of nurses’ work depreciation. Chosen aspects. Journal of Education, Health and Sport. 2016;6(10):11-21. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.159507 http://ojs.ukw.edu.pl/index.php/johs/article/view/3920       The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2...

Ergonomics and design in the Brazilian agricultural sector: a proposal to build matrix of contradictions.

Science.gov (United States)

Tosetto, Thaís; Camarotto, João Alberto

2012-01-01

The paper presents a correlation between the parameters of classical TRIZ and variables of analysis of the EWA to construct a matrix of contradictions in ergonomics, with the objective of assisting the designing processes in the Brazilian agricultural sector. Given the representativeness of the sector in the economy, the boundary conditions in which the activities are developed and their impact on the health of workers, this proposal should contribute to the development of adaptable solutions and the promotion of Decent Work.

School adolescents' knowledge concerning hepatitis C virus (HCV)

OpenAIRE

Sierpińska, Lidia; Jankowska, Ewa

2017-01-01

Sierpińska Lidia, Jankowska Ewa. School adolescents’ knowledge concerning hepatitis C virus (HCV). Journal of Education, Health and Sport. 2017;7(1):11-27. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.229140 http://ojs.ukw.edu.pl/index.php/johs/article/view/4133 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 754 (09.12.2016). 754 Journal of Education, Health and Sport eISSN 2391-8306 7 © Th...

EDITORIAL: Microwave Moisture Measurements

Science.gov (United States)

Kaatze, Udo; Kupfer, Klaus; Hübner, Christof

2007-04-01

Microwave moisture measurements refer to a methodology by which the water content of materials is non-invasively determined using electromagnetic fields of radio and microwave frequencies. Being the omnipresent liquid on our planet, water occurs as a component in most materials and often exercises a significant influence on their properties. Precise measurements of the water content are thus extremely useful in pure sciences, particularly in biochemistry and biophysics. They are likewise important in many agricultural, technical and industrial fields. Applications are broad and diverse, and include the quality assessment of foodstuffs, the determination of water content in paper, cardboard and textile production, the monitoring of moisture in sands, gravels, soils and constructions, as well as the measurement of water admixtures to coal and crude oil in reservoirs and in pipelines. Microwave moisture measurements and evaluations require insights in various disciplines, such as materials science, dielectrics, the physical chemistry of water, electrodynamics and microwave techniques. The cooperation of experts from the different fields of science is thus necessary for the efficient development of this complex discipline. In order to advance cooperation the Workshop on Electromagnetic Wave Interaction with Water and Moist Substances was held in 1993 in Atlanta. It initiated a series of international conferences, of which the last one was held in 2005 in Weimar. The meeting brought together 130 scientists and engineers from all over the world. This special issue presents a collection of some selected papers that were given at the event. The papers cover most topics of the conference, featuring dielectric properties of aqueous materials, electromagnetic wave interactions, measurement methods and sensors, and various applications. The special issue is dedicated to Dr Andrzej W Kraszewski, who died in July 2006 after a distinguished career of 48 years in the research of

Epigenome-wide association study of DNA methylation in narcolepsy: an integrated genetic and epigenetic approach.

Science.gov (United States)

Shimada, Mihoko; Miyagawa, Taku; Toyoda, Hiromi; Tokunaga, Katsushi; Honda, Makoto

2018-04-01

Narcolepsy with cataplexy, which is a hypersomnia characterized by excessive daytime sleepiness and cataplexy, is a multifactorial disease caused by both genetic and environmental factors. Several genetic factors including HLA-DQB1*06:02 have been identified; however, the disease etiology is still unclear. Epigenetic modifications, such as DNA methylation, have been suggested to play an important role in the pathogenesis of complex diseases. Here, we examined DNA methylation profiles of blood samples from narcolepsy and healthy control individuals and performed an epigenome-wide association study (EWAS) to investigate methylation loci associated with narcolepsy. Moreover, data from the EWAS and a previously performed narcolepsy genome-wide association study were integrated to search for methylation loci with causal links to the disease. We found that (1) genes annotated to the top-ranked differentially methylated positions (DMPs) in narcolepsy were associated with pathways of hormone secretion and monocarboxylic acid metabolism. (2) Top-ranked narcolepsy-associated DMPs were significantly more abundant in non-CpG island regions and more than 95 per cent of such sites were hypomethylated in narcolepsy patients. (3) The integrative analysis identified the CCR3 region where both a single methylation site and multiple single-nucleotide polymorphisms were found to be associated with the disease as a candidate region responsible for narcolepsy. The findings of this study suggest the importance of future replication studies, using methylation technologies with wider genome coverage and/or larger number of samples, to confirm and expand on these results.

Costs and benefits of biological control of invasive alien plants in South Africa

CSIR Research Space (South Africa)

Van Wilgen, BW

2011-08-01

Full Text Available ba se d on w ate r pr od uc tio n, w ild flo we r ha rv es t, hik er vis ita tio n, ecotourism ,endemi cspecie san dgeneti cstorage . Valu ewa s US$ 3millio n (wit hn o managemen to falie n plants) ,an... is the most important), and on poverty alleviation (through the employment of disadvantaged people in rural areas). Currently, WfW has an annual operating budget of approxi- mately R500 million, and the way in which this budget is subdivided provides...

Przygotowanie pacjentów z cukrzycą typu 2 do profilaktyki zespołu stopy cukrzycowej = Preparing patients with type 2 diabetes to prophylaxis of diabetic foot

OpenAIRE

Kropornicka, Beata; Baczewska, Bożena; Dadej, Aleksandra; Krzyżanowska, Ewa; Łuczyk, Robert; Olszak, Cecylia; Nowicka, Elżbieta; Lorencowicz, Regina; Muraczyńska, Bożena

2016-01-01

Kropornicka Beata, Baczewska Bożena, Dadej Aleksandra, Krzyżanowska Ewa, Łuczyk Robert, Olszak Cecylia, Nowicka Elżbieta, Lorencowicz Regina, Muraczyńska Bożena. Przygotowanie pacjentów z cukrzycą typu 2 do profilaktyki zespołu stopy cukrzycowej = Preparing patients with type 2 diabetes to prophylaxis of diabetic foot. Journal of Education, Health and Sport. 2016;6(11):311-324. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.167141 http://ojs.ukw.edu.pl/index.php/johs/article/view/3...

Zaburzenia odżywiania – problem wciąż aktualny = Eating disorders – an ongoing problem

OpenAIRE

Rzońca, Ewa; Bień, Agnieszka; Iwanowicz-Palus, Grażyna

2016-01-01

Rzońca Ewa, Bień Agnieszka, Iwanowicz-Palus Grażyna. Zaburzenia odżywiania – problem wciąż aktualny = Eating disorders – an ongoing problem. Journal of Education, Health and Sport. 2016;6(12):267-273. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.198734 http://ojs.ukw.edu.pl/index.php/johs/article/view/4053 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015). 755 Journal of Edu...

Zaburzenia odżywiania – problem wciąż aktualny = Eating disorders – an ongoing problem

OpenAIRE

Ewa Rzońca; Agnieszka Bień; Grażyna Iwanowicz-Palus

2016-01-01

Rzońca Ewa, Bień Agnieszka, Iwanowicz-Palus Grażyna. Zaburzenia odżywiania – problem wciąż aktualny = Eating disorders – an ongoing problem. Journal of Education, Health and Sport. 2016;6(12):267-273. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.198734 http://ojs.ukw.edu.pl/index.php/johs/article/view/4053         The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015). 755 Journal of Educa...

Analysis of Field Activity Perspectives of Centralized Non-Appropriated Fund Accounting, Banking, and Payroll Procedures within the Department of the Navy.

Science.gov (United States)

1982-06-01

4 aN U N J G - @ N 4 0 49 "f*U’ aW ..- fta .0* IAU = 0 6~ U) x 3. -- a- - U N N j w .0 46FANU an4 U 4 ~ ~ ~ ~ ~ l UN 4 . E r- a , a- X a.I IL0.2.a’ a...Planning and Management 204 1I 3 374%A622 USEPIES OF THE FMD SOL==C SECTION OP E!WAS BAIA= M AID E Tota Number of Acti.ities for Wbhch Basponws Were ftn

Od melancholii do rozpaczy. O prozie Andrzeja Stasiuka

Directory of Open Access Journals (Sweden)

Claudia Snochowska-Gonzalez

2014-06-01

Full Text Available From melancholy to despair. About Andrzej Stasiuk’s prose works In Moja Europa, Jadąc do Babadag and Fado Andrzej Stasiuk describes his travelling to the countries of the East-Central Europe: its diminished, forgotten part, lying on the margins of History and Progress. It is a land of melancholy, of the eternal emptiness and lack. To praise it means to give an ironic response to the enthusiasm of a “return to the West”, to the attempts to meet East-European stigma and to the West’s fear of East-European ferocity. What is the source of this melancholy? Stasiuk refers to Cioran, his philosophy of history, his resignation and his belief in the bankruptcy of the European civilization. We know, however, that in the case of Cioran melancholy covers the memory of philosopher’s commitment to Romanian fascism; his subsequent melancholy replaces responsibility. What are the wounds and silenced victims hiding in Stasiuk’s melancholic landscape? What kind of responsibility does he not want to accept? In his next book, Dziennik pisany później, Stasiuk comes back to the same countries, this time not trying to escape the hell of questions about the East-European ethnic carnage. The author of the article analyses his turning point, using the terminology developed in Peter Hallward’s Absolutely Post-colonial to describe the dynamics between two tendencies: singular and specific.   Od melancholii do rozpaczy. O prozie Andrzeja Stasiuka W Mojej Europie, Jadąc do Babadag i Fado Andrzej Stasiuk podróżuje po krajach Europy Środkowo-Wschodniej. To Europa pomniejsza, zapomniana, na marginesie Historii i Postępu. Jest to kraina melancholii, pustki i wiecznego braku. Opiewanie jej staje się ironiczną odpowiedzią na entuzjazm „powrotu do Zachodu”, na próby sprostania wschodnioeuropejskiemu piętnu i na zachodnie przerażenie wschodnioeuropejską dzikością. Skąd się jednak bierze spowijająca ją melancholia? Stasiuk powołuje się na

SOCIAL PARTICIPATION IN THE ENVIRONMENTAL FLOW ASSESSMENT: THE SÃO FRANCISCO RIVER CASE STUDY

Directory of Open Access Journals (Sweden)

Yvonilde Dantas Pinto Medeiros

2013-03-01

Full Text Available Traditionally, water resource management has been developed using an essentially technical approach. Currently, public opinion on water resource management is formed as a result of growing environmental concerns and social conflicts arising from poorly planned actions. Environmental problems are complex and have multiple dimensions, including social and economic. Therefore, the inclusion of a human dimension in integrated assessment methodologies is required for the introduction of new elements to the water management planning process. Environmental water allocation (EWA is understood as the quantity, quality and distribution of water required for the maintenance of the functions and processes of aquatic ecosystems on which people depend. Within the various holistic assessment methodologies, the Building Block Methodology (BBM was found to be the most suitable, in the Brazilian context, for maintaining and restoring essential elements of the natural flow regime. This article describes the process of social participation in the environmental flow assessment (EFA for the Sao Francisco River, and compares it with some of the lessons learned from EFA in other parts of the world. The process involved multiple stakeholders who have conflicting interests. BBM was used to guide the field interviews, to incorporate the empirical observations by the local population and to guide the methodological procedures of the multidisciplinary team. The results of the study indicate the effectiveness of this holistic approach in organizing the elements to be evaluated. It also facilitated important contributions to the establishment of a dialogue between the actors to achieve a better understanding of the multiple aspects involved in the decisions associated with the EWA.

General Aviation Activity and Avionics Survey 1982.

Science.gov (United States)

1983-12-01

is F- C- i I.. <Z< 04K 4 K 4 K mm <.1 -.5 9.JO M 5 I. .J0 - AI. C 1.-’ 01- 1 0 0 -. t- 0 t- a 00 o 0 o0 mo0 w 0 is owe ao Ewa wm wo iso - 24 .0 4%~ 4...0540 41531 PCKARDV1650 49001 FRNKLN4AC50 27002 LYC 0540 41532 PWA 6T02 dT12 FRNKLN4AC0 27003 LYC 0540 41533 PWA JT12 52042 FRNKLN4AC10 27004 LYC 0540

Response to “Oral health in the elderly patient and its impact on general well-being: a nonsystematic review” paper

Directory of Open Access Journals (Sweden)

Muc-Wierzgoń M

2015-05-01

Full Text Available Malgorzata Muc-Wierzgoń, Teresa Kokot, Ewa Nowakowska-Zajdel, Adam Błażelonis, Edyta Fatyga Department of Internal Medicine, Silesian Medical University, Bytom, PolandDear editorGil-Montoya et al has recently published an interesting article in Clinical Interventions in Aging entitled: “Oral health in the elderly patient and its impact on general well-being: a nonsystematic review”.1 Authors presented a non-systematic review of the published data regarding the oral health status of the elderly and its main repercussions, including its impact on general health and nutrition.View original paper by Gil-Montoya and colleagues.

Biskup Adolf Piotr Szelążek w Zamku Bierzgłowskim (1946-1950)

OpenAIRE

Rozynkowski, Waldemar

2018-01-01

Od kilku lat niezwykle dynamicznie rozwijają się badania nad życiem i posługą ordynariusza diecezji łuckiej na Wołyniu biskupa Adolfa Piotra Szelążka (1865-1950). Związane jest to na pewno z podjętymi staraniami o wyniesienie biskupa na ołtarze. Dnia 9 lutego 2010 roku biskup toruński Andrzej Suski powołał Komisję Historyczną, której zadaniem było przeprowadzenie szczegółowej kwerendy źródłowej dotyczącej osoby biskupa Szelążka i przygotowanie materiałów do procesu beatyfikacyjnego. Jej skła...

“My” “Musical” “Language” ?

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Augustyn Rafał

2015-12-01

Full Text Available The problem associated with the musical “language” of a particular composer can be understood either literally, i.e. with some possible analogies to natural language, or metaphorically, as a substitute of style, technique, or manner. I try to combine both usages. In fact, my approach to composing music is not so much - to develop a consistent language ready for use in multiple instances and thus to attain a recognisable personal style, but rather - to try to build a tool for use in one particular composition on many levels of musical “grammar”. Another basic problem is the proportion between impulse and design as defined in a well-known book by Andrzej Panufnik.

Od teatru okrucieństwa do Grand Guignolu. Śmierć w kinie Andrzeja Żuławskiego

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Jacek Nowakowski

2007-08-01

Full Text Available This essay shows the motif of death in the film works of Andrzej Żuławski in the perspective of the theatre of horror. Starting with Trzecia część nocy (The Third Part of the Night (1971 until his late work Szamanka (The Shaman Woman (1996, this film work is shown as evolving from the patronage of the conception of art of Antonin Artaud, serving the transformation of man up to its peculiar autoparody, which is closer to Grand Guignol. The author proves that escalation of cruelty in his works gradually loses its artistic pretext (justification ceases to be artistically justified (no longer find artistic justification.

S-adenosylmethionine blocks osteosarcoma cells proliferation and invasion in vitro and tumor metastasis in vivo: therapeutic and diagnostic clinical applications

International Nuclear Information System (INIS)

Parashar, Surabhi; Cheishvili, David; Arakelian, Ani; Hussain, Zahid; Tanvir, Imrana; Khan, Haseeb Ahmed; Szyf, Moshe; Rabbani, Shafaat A

2015-01-01

Osteosarcoma (OS) is an aggressive and highly metastatic form of primary bone cancer affecting young children and adults. Previous studies have shown that hypomethylation of critical genes is driving metastasis. Here, we examine whether hypermethylation treatment can block OS growth and pulmonary metastasis. Human OS cells LM-7 and MG-63 were treated with the ubiquitous methyl donor S-adenosylmethionine (SAM) or its inactive analog S-adenosylhomocystine (SAH) as control. Treatment with SAM resulted in a dose-dependent inhibition of tumor cell proliferation, invasion, cell migration, and cell cycle characteristics. Inoculation of cells treated with 150 μmol/L SAM for 6 days into tibia or via intravenous route into Fox Chase severe combined immune deficient (SCID) mice resulted in the development of significantly smaller skeletal lesions and a marked reduction in pulmonary metastasis as compared to control groups. Epigenome wide association studies (EWAS) showed differential methylation of several genes involved in OS progression and prominent signaling pathways implicated in bone formation, wound healing, and tumor progression in SAM-treated LM-7 cells. Real-time polymerase chain reaction (qPCR) analysis confirmed that SAM treatment blocked the expression of several prometastatic genes and additional genes identified by EWAS analysis. Immunohistochemical analysis of normal human bone and tissue array from OS patients showed significantly high levels of expression of one of the identified gene platelet-derived growth factor alpha (PDGFA). These studies provide a possible mechanism for the role of DNA demethylation in the development and metastasis of OS to provide a rationale for the use of hypermethylation therapy for OS patients and identify new targets for monitoring OS development and progression

Content and Symbolics of Polychromy in Cistercian Church in Jędrzejów (outline of issues

Directory of Open Access Journals (Sweden)

Lucyna Rotter

2004-12-01

Full Text Available A close theological and artistic co-operation has been observed in religious art since the Middle Ages. In the Baroque this co-operation was best revealed in monumental decorations inside churches. An example of it is the polychromy in the abbot church in Jędrzejów, whose author was Andrzej Radwański. Intention plan includes both theological content and issues connected with spirituality and activity of the Cistercian order. The history of the Jędrzejów Abbey was particularly emphasized and so was the person of the Blessed Wincenty Kadłubek, who was connected with it. A correlation between historical and symbolical depictions is very interesting; a method often used by Radwański in his monumental decorative painting.

Auhinnad 2009 - Nike ja Gdynia / Hendrik Lindepuu

Index Scriptorium Estoniae

Lindepuu, Hendrik, 1958-

2009-01-01

Poola tähtsaima kirjandusauhinna Nike sai 2009. aastal luuletaja Eugeniusz Tkaczyszyn-Dycki luulekogu "Piosenka o zależnościach i uzależnieniach" ("Laul sõltuvusest ja sõltumusest") eest. Teised kandidaadid olid: Andrzej Barti romaan "Fabryka muchołapek" ("Kärbsepiitsavabrik"), Ignacy Karpowiczi romaan "Gesty" ("Žestid"), Inga Iwasiówi romaan "Bambino", Bohdan Sławiński romaan "Królowa tiramisu" ("Tiramisu kuninganna"), Tomasz Piąteki romaan "Pałac Ostrogskich" ("Ostrogski loss") ja Krzystof Varga esseekogumik "Gulasz z turula" ("Turuguljašš"). Gdynia preemia luuleauhinna sai Eugeniusz Tkaczyszyn-Dycki luulekogu "Piosenka o zależnościach i uzależnieniach" ("Laul sõltuvusest ja sõltumusest"), proosapreemia sai Marcin Świetlicki romaan "Jedenście" ("Üksteist")

Dokumentalny świat Andrzeja Wajdy

Directory of Open Access Journals (Sweden)

Katarzyna Mąka-Malatyńska

2017-12-01

Full Text Available The article introduces a relatively unknown aspect of Andrzej Wajda’s output – his documentary films. The author examines documentaries on art and autobiographical film, which usually comprise glosses on feature films. These non-fiction films, like Wajda's best-known movies, refer to the codes of Polish culture, created by art and literature, and thanks to which the creative output of the maker of Afterimage (Powidoki appears to unusually coherent and consistent, regardless of the genealogical classification. The author selects examples to analyse the connections between Wajda’s feature films and the conventions of the documentary. Wajda’s overriding aim in using the poetics of documentary is in each case to undertake mise-en-abîme reflections.

Andrzej Karpowicz – twórca Pracowni Zbiorów Masońskich Biblioteki Uniwersyteckiej w Poznaniu

Directory of Open Access Journals (Sweden)

Tomasz Kurzawa

2011-01-01

Full Text Available Artykuł omawia działalność naukową i zasługi w zakresie pracy bibliotecznej twórcy Pracowni Zbiorów Masońskich Biblioteki Uniwersyteckiej – mgra Andrzeja Karpowicza. Portret Andrzeja Karpowicza przedstawiony został na szerokim tle piśmiennictwa i źródeł do dziejów wolnomularstwa oraz sylwetek autorów zajmujących się wskazaną problematyką.

Activities in the field of nuclear reactor instrumentation and control in Poland - 1991 status

International Nuclear Information System (INIS)

Mikulski, A.T.

1992-01-01

The report gives a condensed overview of activity in the field of nuclear reactor instrumentation and control in Poland over the last few years. The work was performed parallel in two directions related to the construction of the first Nuclear Power Plant at Zarnowlec and to the changes made for two research reactors at Swierk. The first direction, according to government decision, was cancelled at the end of 1990 and the results obtained up to now are briefly summarized. The second one is in progress, some minor changes in I and C for the EWA reactor and significant improvements for the MARIA reactor are under way. The results of this activity are presented. (author). 6 refs

Differentially Methylated DNA Regions in Monozygotic Twin Pairs Discordant for Rheumatoid Arthritis

DEFF Research Database (Denmark)

Svendsen, Anders J; Gervin, Kristina; Lyle, Robert

2016-01-01

: Smoking was significantly associated with hypomethylation of a DMR overlapping the promoter region of the RNF5 and the AGPAT1, which are implicated in inflammation and autoimmunity, whereas DMARD treatment induced hypermethylation of the same region. Additionally, the promotor region of both S100A6......OBJECTIVES: In an explorative epigenome-wide association study (EWAS) to search for gene independent, differentially methylated DNA positions and regions (DMRs) associated with rheumatoid arthritis (RA) by studying monozygotic (MZ) twin pairs discordant for RA. METHODS: Genomic DNA was isolated......: We identified several differentially methylated regions associated with RA, which may represent environmental effects or consequences of the disease and plausible biological pathways pertinent to the pathogenesis of RA....

Les séries polonaises des années 1970 : entre contraintes politiques et censures génériques

Directory of Open Access Journals (Sweden)

Ania Szczepanska

2011-04-01

Full Text Available Dans les années 70, le directeur de la télévision polonaise lance la « propagande du succès », une ligne éditoriale censée refléter au petit écran la modernisation économique du pays. C’est à cette époque qu’est produite la série culte des Polonais : Le Quarantenaire. Dix ans plus tard et en plein état de guerre, une autre série connaîtra un grand succès, Jean le Cœur. Les deux séries sont produites par le groupe de production X, dirigé par Andrzej Wajda et connu au contraire pour ses films d’auteur du cinéma de l’inquiétude morale. Comment expliquer cette alliance inattendue entre télévision et cinéma ? Cette origine cinématographique a-t-elle marqué l’écriture filmique des deux séries télévisées ? La sérialité permet-elle de penser autrement la réalité socialiste ?In the seventies, the director of Polish Television launched the "success propaganda", an editorial line supposed to be the TV portrayal of the nation's economic modernisation. During that period the cult Polish series Middle-aged man [Czterdziestolatek] was produced. Ten years later, in the heat of the wartime period, another series had great success: John Heart [Jan Serce]. Both series were produced by the production group "X", headed by Andrzej Wajda, and were better known for producing independent films that were part and parcel of a cinema that expressed moral concern. How can this unexpected alliance between TV and the cinema be explained? Did the cinema-oriented producers influence the filmic grammar of the two series? Can cinematographers use the tools of TV series to express a socialist reality in a different way?

Gombrowicz a polski film fabularny

Directory of Open Access Journals (Sweden)

Jacek Nowakowski

2013-01-01

Full Text Available This article presents the influence that Witold Gombrowicz’s work has had on Polish cinema. It covers several generations of directors, for example, Andrzej Munk (born in the 1920s, Roman Polański and Jerzy Skolimowski (born in the 1930 as well as Agnieszka Holland, Piotr Szulkin and Marek Koterski (born in the 1940s and 1950s, and discusses the topic of film adaptations of his books (Jerzy Skolimowski’s Ferdydurke and Jan Jakub Kolski’s Pornografia [Pornography]. The article shows that Polish cinema uses Gombrowicz’s works most of all by taking up the issue of life’s authenticity and inauthenticity as well as to demythologize Polish tradition and history. As for esthetics, it employs Gombrowicz’s favorite style, i.e. the grotesque.

8 February 2017 - Sri Lanka Hon. Minister of Science, Technology and Research A. D. S. Premajayantha signing the International Cooperation Agreement concerning Scientific and Technical Cooperation in High-Energy Physics 2017 with CERN Director for International Relations C. Warakaulle.

CERN Multimedia

Brice, Maximilien

2017-01-01

Were present: Hon. A. D. Susil Premajayantha, Minister of Science, Technology and Research, Democratic Socialist Republic of Sri Lanka; H.E. Mr Ravinatha Aryasinha, Ambassador, Permanent Representative of Sri Lanka to the UN in Geneva; Mrs Samantha Jayasuriya, Deputy Permanent Representative, Permanent Mission of Sri Lanka to the UN in Geneva; Ms Shashika Somaratne, Counsellor, Permanent Mission of Sri Lanka to the UN in Geneva; Mr Gihan Indragupta, Member of Sri Lanka Foreign service and Head of the G15 Secretariat; Ms Dilini Gunasekera, Second Secretary, Permanent Mission of Sri Lanka to the UN in Geneva; Mr Prageeth Herath , Supporting staff, Permanent Mission of Sri Lanka. CERN: Mr Andrzej Charkiewicz, CMS Ressources Manager; Ms Sofia Intoudi, Legal Officer; Dr Rüdiger Voss, Senior Adviser, International Relations; Ms Charlotte Warakaulle, Director for International Relations

A fruitful encounter between Cognitive Science and Science & Technology Studies

Directory of Open Access Journals (Sweden)

Aleksandra Derra

2013-06-01

Full Text Available Scholars deriving from different schools of thought, especially if these grow out of different traditions, do not meet too frequently, and it is even more rare for these meeting to result in creating theories or research practices that would be cognitively surprising or rich in refreshing ideas. Therefore, the material we present in the current issue of Avant (1/2013 is exceptional. In the following part you can read articles by representatives of the so-called Toruń (postconstructivist school, “(Postconstructivism on the subject of techno-science” by Ewa Bińczyk and “A-socio-logy of a condition. A study of controversies surrounding etiology, diagnosis and therapy of ADHD” by Łukasz Afeltowicz and Michał Wróblewski.

Nonlinear optimization

CERN Document Server

Ruszczynski, Andrzej

2011-01-01

Optimization is one of the most important areas of modern applied mathematics, with applications in fields from engineering and economics to finance, statistics, management science, and medicine. While many books have addressed its various aspects, Nonlinear Optimization is the first comprehensive treatment that will allow graduate students and researchers to understand its modern ideas, principles, and methods within a reasonable time, but without sacrificing mathematical precision. Andrzej Ruszczynski, a leading expert in the optimization of nonlinear stochastic systems, integrates the theory and the methods of nonlinear optimization in a unified, clear, and mathematically rigorous fashion, with detailed and easy-to-follow proofs illustrated by numerous examples and figures. The book covers convex analysis, the theory of optimality conditions, duality theory, and numerical methods for solving unconstrained and constrained optimization problems. It addresses not only classical material but also modern top...

Confronting the Past

DEFF Research Database (Denmark)

Bondebjerg, Ib

2013-01-01

Historical films are important carriers of collective memory, and as a genre historical films can activate both strong feelings and strong debate. Historical fiction films often tell very accurate and almost documentary stories, but fictional films have the freedom to make historical reality...... in quite another way than factual historical films. This article deals with some of the most important historical film genres and uses a general theory of genres, emotions, memory and history to analyse the historical films of Polish film director Andrzej Wajda, especially those made post 1989. Dealing...... with both his heritage drama Pan Tadeusz (1999) and critical historical drama Katyn (2007), the article analyses the ways in which Wajda uses historical narratives to comment on both history and contemporary society, and how this strategy is reflected in all his historical films. The article argues...

PREFACE: Joint European Magnetic Symposia - JEMS 2010

Science.gov (United States)

Spałek, Jozef

2011-07-01

łekChairman of JEMS 2010 Symposia 1. Plenary, Semi-plenary, Tutorials 2. Magnetization Processes Spin Excitations and Ultrafast DynamicsCoordinator: Andrzej Maziewski (Bialystok) 3. Hard Magnetic Materials and MagnetocaloricsCoordinator: Henryk Figiel (Kraków) 4. Magnetic HydridesCoordinators: Ladislav Havela (Praha), Zbigniew Tarnawski (Kraków) 5. Interface of Magnetic Thin FilmsCoordinators: Jürgen Fassbender (Dresden), N-T H Kim-Ngan (Kraków) 6. Magnonic CrystalsCoordinators: Bahram Djafari-Rouhani (Lille), Henryk Puszkarski (Poznan) 7. Magnetism of Metals, Alloys, and IntermetallicsCoordinator: Andrzej Szytula (Kraków) 8. Molecular MagnetismCoordinators: Stephen Blundell (Oxford), Maria Balanda (Kraków) 9. Magnetooptics of NanomagnetsCoordinators: Kamil Postava (Ostrava), Marek Kisielewski (Bialystok) 10. NanomagnetismCoordinators: Marek Przybylski (Halle), Jürgen Kirschner (Halle) 11. Other topics - Biomagnetism, Domain Walls, InstrumentationCoordinator: Henryk Figiel (Kraków) 12. Magnetic Perovskites and MultiferroicsCoordinator: Henryk Szymczak (Warszawa) 13. Magnetic Semiconductors and InsulatorsCoordinators: Klaus Baerner (Göttingen), Tadeusz Gron (Katowice) 14. Magnetic Shape Memory Effects and Related PhenomenaCoordinators: Oliver Gutfleisch (Dresden), Sebastian Fähler (Dresden) 15. Soft Magnetic MaterialsCoordinators: Julian González (San Sebastian), Krzysztof Kulakowski (Kraków) 16. SpintronicsCoordinator: Maciej Sawicki (Warszawa) 17. Strongly Correlated Electron Systems, Magnetism and SuperconductivityCoordinator: Andrzej Slebarski (Katowice) The next Joint European Magnetic Symposia, JEMS 2012, will be held in Parma, Italy, 9-14 September 2012.www.jems2012.itCo-Chairs:Franca Albertini, Institute of Materials for Electronics and Magnetism (IMEM), CNR, ParmaRoberto De Renzi, Department of Physics, University of Parma

Jllumina

DEFF Research Database (Denmark)

Almeida, Diogo Marinho; Uhrenfeldt Skov, Ida; Lund, Jesper

2016-01-01

enabling high quality and statistically sound downstream analyses. As of yet, only R-based solutions are freely available for low-level processing of the Illumina chip data. However, the lack of alternative libraries poses a hurdle for the development of new bioinformatic tools, in particular when it comes...... to web services or applications where run time and memory consumption matter, or EWAS data analysis is an integrative part of a bigger framework or data analysis pipeline. We have therefore developed and implemented Jllumina, an open-source Java library for raw data manipulation of Illumina Infinium...... HumanMethylation450 and Infinium MethylationEPIC BeadChip data, supporting the developer with Java functions covering reading and preprocessing the raw data, down to statistical assessment, permutation tests, and identification of differentially methylated loci....

Epigenetics and cerebral organoids

DEFF Research Database (Denmark)

Forsberg, Sheena Louise; Ilieva, Mirolyuba; Maria Michel, Tanja

2018-01-01

also play a role. Some studies indicate a set of candidate genes with different DNA methylation profiles in ASD compared to healthy individuals. Thus epigenetic alterations could help bridging the gene-environment gap in deciphering the underlying neurobiology of autism. However, epigenome......-wide association studies (EWAS) have mainly included a very limited number of postmortem brain samples. Hence, cellular models mimicking brain development in vitro will be of great importance to study the critical epigenetic alterations and when they might happen. This review will give an overview of the state...... of the art concerning knowledge on epigenetic changes in autism and how new, cutting edge expertise based on three-dimensional (3D) stem cell technology models (brain organoids) can contribute in elucidating the multiple aspects of disease mechanisms....

Launch of technical training courses for programmers

CERN Multimedia

2015-01-01

This autumn, two new technical training courses have been launched for scientists and engineers at CERN who undertake programming tasks, particularly in C and C++. Both courses are taught by Andrzej Nowak, an expert in next-generation and cutting-edge computing technology research.   The training courses are organised in cooperation with CERN openlab and are sponsored by the CERN IT department – there is only a nominal registration fee of 50 CHF. This is an opportunity not to be missed! Computer architecture and hardware-software interaction (2 days, 26-27 October) The architecture course offers a comprehensive overview of current topics in computer architecture and their consequences for the programmer, from the basic Von Neumann schema to its modern-day expansions. Understanding hardware-software interaction allows the programmer to make better use of all features of available computer hardware and compilers. Specific architectural ...

Interactive granular computations in networks and systems engineering a practical perspective

CERN Document Server

Jankowski, Andrzej

2017-01-01

The book outlines selected projects conducted under the supervision of the author. Moreover, it discusses significant relations between Interactive Granular Computing (IGrC) and numerous dynamically developing scientific domains worldwide, along with features characteristic of the author’s approach to IGrC. The results presented are a continuation and elaboration of various aspects of Wisdom Technology, initiated and developed in cooperation with Professor Andrzej Skowron. Based on the empirical findings from these projects, the author explores the following areas: (a) understanding the causes of the theory and practice gap problem (TPGP) in complex systems engineering (CSE);(b) generalizing computing models of complex adaptive systems (CAS) (in particular, natural computing models) by constructing an interactive granular computing (IGrC) model of networks of interrelated interacting complex granules (c-granules), belonging to a single agent and/or to a group of agents; (c) developing methodologies based ...

Analysis of the workload of bank tellers of a Brazilian public institution.

Science.gov (United States)

Serikawa, Simoni S; Albieri, Ana Carolina S; Bonugli, Gustavo P; Greghi, Marina F

2012-01-01

During the last decades there have been many changes in the banking sector organization. It has been also observed the mutual growing of musculoskeletal and mental disorders. This study investigated the workload of bank tellers at a Brazilian public institution. It was performed the Ergonomic Work Analysis (EWA). Three employees participated in this study. During the analysis process, three research instruments were applied: Inventory of Work and Risk of Illness, Yoshitake Fatigue Questionnaire and Nordic Musculoskeletal Questionnaire, beyond the realization of footage recordings and the self-confrontation. The results indicated the existence of an excess of workload on the evaluated workstations, mainly in relation to mental order constraints, that overlaps the physical aspects. Thereby it was found that the employees tend to adopt strategies trying to reduce the impacts of the excess of workload, in order to regulate it.

Kolory poezji (Na przykładzie poezji lirycznej Konstantego Ildefonsa Gałczyńskiego

Directory of Open Access Journals (Sweden)

Agnieszka Rydz

2016-06-01

Full Text Available The article presents the category of colour in modern Polish poetry, and based on an interpretation of Ewa Górecka’s book, Konstatnego Ildefonsa Gałczyńskiego gry barwą z wyobraźnią i kulturą [Colours as Konstanty Ildefons Gałczyński’s Play with Imagination and Culture]. The colour palette in Gałczyński’s poetry includes golden, silver, green, blue, red and black. Culture was an inspiration for the poet, but he didn’t avoid entering into dialogue with it, establishing the meanings of colours in his writing. The colours present in Gałczyński’s lyric poetry also indicate the changes in his poetic language. The way in which the poet uses them in his early works differs from their use in those created after 1945.

Efficient detection of differentially methylated regions using DiMmeR

DEFF Research Database (Denmark)

Almeida, Diogo Marinho; Uhrenfeldt Skov, Ida; Silva, Artur

2017-01-01

in the programming language R, have no user interface, and do not offer all necessary steps to guide users from raw data all the way down to statistically significant differentially methylated regions (DMRs) and the associated genes. RESULTS: Here, we present DiMmeR (Discovery of Multiple Differentially Methylated...... Regions), the first free standalone software that interactively guides with a user-friendly graphical user interface (GUI) scientists the whole way through EWAS data analysis. It offers parallelized statistical methods for efficiently identifying DMRs in both Illumina 450K and 850K EPIC chip data. Di......MmeR computes empirical p-values through randomization tests, even for big data sets of hundreds of patients and thousands of permutations within a few minutes on a standard desktop PC. It is independent of any third-party libraries, computes regression coefficients, p-values and empirical p...

Awards aplenty in Krakow

CERN Multimedia

2009-01-01

CERN will be well represented this year at the award ceremony organized by the European Physical Society (EPS) in Krakow. The Gargamelle Collaboration is being awarded the High Energy and Particle Physics prize, while Maurizio Pierini shares the Young Physicist Prize. Both Mick Storr and Andrzej Siemko will be awarded the Medal of the Polish Commission of National Education.This year’s EPS-High Energy and Particle Physics Prize is being awarded to the Gargamelle Collaboration for the discovery of the weak neutral current. Gargamelle’s large bubble chamber is now displayed in the Microcosm garden at CERN in commemoration of the discovery that led to the acceptance of the electroweak theory and the award of the Noble prize to Glashow, Salam and Weinberg in 1979. On 3 September 1973 the collaboration published two papers in the same issue of Physics Letters, one on neutral currents involving electrons, the other on neutral current interactions with hadrons (protons and neut...

Academic Training Lectures | Introduction to Parallelism, Concurrency and Acceleration | 19-20 January

CERN Multimedia

2016-01-01

Please note that the next series of Academic Training Lectures will take place on 19 and 20 January 2016. The lectures will be given by Andrzej Nowak (TIK Services, Switzerland).   An Introduction to Parallelism, Concurrency and Acceleration (1/2) on Tuesday, 19 January from 11 a.m. to 12 noon https://indico.cern.ch/event/404682/ An Introduction to Parallelism, Concurrency and Acceleration (2/2) on Wednesday, 20 January from 11 a.m. to 12 noon https://indico.cern.ch/event/404683/ at CERN IT Amphitheatre (31-3-004) Description: Concurrency and parallelism are firm elements of any modern computing infrastructure, made even more prominent by the emergence of accelerators. These lectures offer an introduction to these important concepts. We will begin with a brief refresher of recent hardware offerings to modern-day programmers. We will then open the main discu...

Digitisation and public accessibility of old Polish guides on self-treatment and quality-of-life improvement

Directory of Open Access Journals (Sweden)

Joanna Nowak

2017-06-01

Full Text Available This letter to the Editor can prove useful as a mini-guide. Interest in health and quality of life is continuing to grow in the second decade of the 21st century, both among professionals actively involved in giving advice to others and among diverse social groups, as well as individually, among those sick and those healthy. Along with recent novelties, traditional Old Polish methods also feature prominently in discussions, but those interested know relatively little about how to access source materials. This letter therefore describes the possibilities for open access to Polish-language health guides from the Renaissance and Baroque era, whose authors included medical doctors and which focused on describing food and herbs used in self-treatment and promoting the healthy life style of the period. The works of Andrzej from Kobylin, Zawacki, Śleszkowski, Olszowski and Haur are briefly described and information is given about their availability in full-text on-line data bases.

Recent developments on the role of epigenetics in obesity and metabolic disease.

Science.gov (United States)

van Dijk, Susan J; Tellam, Ross L; Morrison, Janna L; Muhlhausler, Beverly S; Molloy, Peter L

2015-01-01

The increased prevalence of obesity and related comorbidities is a major public health problem. While genetic factors undoubtedly play a role in determining individual susceptibility to weight gain and obesity, the identified genetic variants only explain part of the variation. This has led to growing interest in understanding the potential role of epigenetics as a mediator of gene-environment interactions underlying the development of obesity and its associated comorbidities. Initial evidence in support of a role of epigenetics in obesity and type 2 diabetes mellitus (T2DM) was mainly provided by animal studies, which reported epigenetic changes in key metabolically important tissues following high-fat feeding and epigenetic differences between lean and obese animals and by human studies which showed epigenetic changes in obesity and T2DM candidate genes in obese/diabetic individuals. More recently, advances in epigenetic methodologies and the reduced cost of epigenome-wide association studies (EWAS) have led to a rapid expansion of studies in human populations. These studies have also reported epigenetic differences between obese/T2DM adults and healthy controls and epigenetic changes in association with nutritional, weight loss, and exercise interventions. There is also increasing evidence from both human and animal studies that the relationship between perinatal nutritional exposures and later risk of obesity and T2DM may be mediated by epigenetic changes in the offspring. The aim of this review is to summarize the most recent developments in this rapidly moving field, with a particular focus on human EWAS and studies investigating the impact of nutritional and lifestyle factors (both pre- and postnatal) on the epigenome and their relationship to metabolic health outcomes. The difficulties in distinguishing consequence from causality in these studies and the critical role of animal models for testing causal relationships and providing insight into underlying

Epigenome-Wide Association Study of Cognitive Functioning in Middle-Aged Monozygotic Twins

DEFF Research Database (Denmark)

Starnawska, Anna; Tan, Qihua; McGue, Matt

2017-01-01

As the world's population ages, the age-related cognitive decline presents a great challenge to world's healthcare systems. One of the molecular mechanisms implicated in cognitive ageing is DNA methylation, an epigenetic modification known to be a key player in memory formation, maintenance......, and synaptic plasticity. Using the twin design we performed an epigenome-wide association study (EWAS) in a population of 486 middle-aged monozygotic twins (mean age at follow-up 65.9, SD = 6.1) and correlated their blood DNA methylation to their level (cross-sectional analysis) and change in cognitive...... abilities over 10 years (longitudinal analysis). We identified several CpG sites where cross-sectional cognitive functioning was associated with DNA methylation levels. The top identified loci were located in ZBTB46 (p = 5.84 × 10-7), and TAF12 (p = 4.91 × 10-7). KEGG's enrichment analyses of the most...

Investigation of the neutron detection statistics in fast critical assembly BFS-24-1

International Nuclear Information System (INIS)

Avramov, A.M.; Tyutyunnikov, P.L.; Mikulski, A.T.; Rafalska, E.; Chwaszczewski, S.; Jablonski, K.

1974-01-01

The results of the neutron detection statistics investigation at the fast critical assembly BFS-24-1 are given. The Ross-α measurements were carried out using: digital flash-start unit and 256 channel time analyzer, 10 channel time analyzer, alphameter device. Parallely the measurements using the variable dead time method and zero probability method were performed. The prompt neutron decay constants, the effectiveness of neutron detector and the intensity of external neutron source are determined using the experimental data. The experimental values of prompt neutron decay constant are compared with the calculated ones. The codes used in the calculation are following: one dimensional, diffusion, 26-group code 26-M and EWA-1, one dimensional, multiregion, nonstationary diffusion 3-group code SPECTR, 26-group, diffusion code in buckling approximation, MIXSPECTR. In all codes the 26 group nuclear constants BNAB-26 and BNAB-70 are used. (author)

Neutrino physics in the spotlight

CERN Multimedia

2009-01-01

Following on from the Council recommendation made in Lisbon in 2006 and responding to the needs of a large community of scientists, CERN will organize the European Strategy for Future Neutrino Physics workshop on 1-3 October. One of the main goals of the workshop is to start establishing a roadmap for the coherent participation of Europe in neutrino physics."The format of the workshop will consist of invited talks to present the current situation and future possibilities; unlike other workshops, 30% of the time will be reserved for discussion", explains Ewa Rondio from the organising committee. "Resources for future neutrino experiments will be difficult to acquire. A coordinated approach and the participation of a large community of interested scientists are undoubtedly crucial factors". The workshop will be the opportunity to highlight the areas where substantial research and development activities are required in order to design the facilities of the next decade. "The w...

New insights and updated guidelines for epigenome-wide association studies

Directory of Open Access Journals (Sweden)

Lisa H. Chadwick

2015-01-01

Full Text Available Epigenetic dysregulation in disease is increasingly studied as a potential mediator of pathophysiology. The epigenetic events are believed to occur in somatic cells, but the limited changes of DNA methylation in studies to date indicate that only subsets of the cells tested undergo epigenetic dysregulation. The recognition of this subpopulation effect indicates the need for care in design and execution of epigenome-wide association studies (EWASs, paying particular attention to confounding sources of variability. To maximize the sensitivity of the EWASs, ideally, the cell type mediating the disease should be tested, which is not always practical or ethical in human subjects. The value of using accessible cells as surrogates for the target, disease-mediating cell type has not been rigorously tested to date. In this review, participants in a workshop convened by the National Institutes of Health update EWAS design and execution guidelines to reflect new insights in the field.

Natural gas in Eastern Europe

Energy Technology Data Exchange (ETDEWEB)

Grabarczyk, Ewa; McCallum, Robert; Wergeland, Tor H

1994-12-31

The paper is based on Ewa Grabarczyk`s thesis ``The European Gas Market and the Former East Block Countries`` in the Master of International Business Programme at the Norwegian School of Economics and Business Administration. The material of Grabarczyk`s work has been split into two parts; SNF Working Papers Nos. 97/93 and 98/93. Working Paper 97/93 ``The European Gas Markets`` contains an equilibrium model of the European Gas Market employed to investigate some scenarios to the consequences of an integration of the former Soviet Union. Working Paper 98/93 ``Natural Gas in Eastern Europe`` contains descriptions of the energy sectors of former Eastern European countries and an evaluation of the potential future demand for natural gas in these nations. The paper has chapters on each country and sections on reserves, production, exports and markets, transport possibilities and technology, demand and development as well as evaluation of the present situation. 11 figs., 37 tabs., 33 refs

Nobel prize-winner Heinrich Rohrer visits CERN

CERN Document Server

2008-01-01

The Nobel prize-winner Heinrich Rohrer met young scientists on a recent visit to the Laboratory. From left to right: Xavier Gréhant (CERN Openlab), Ewa Stanecka (ATLAS), Magda Kowalska (ISOLDE), Heinrich Rohrer, Stéphanie Beauceron (CMS) and Ana Gago Da Silva (UNOSAT).Heinrich Rohrer, who shared the 1986 Nobel prize for physics with Gerd Binnig for the design of the scanning tunnelling microscope, visited CERN on 25 June. Welcomed by the Director-General, Robert Aymar, he visited the ATLAS cavern and control room, the Computer Centre, the Unosat project, the Antimatter Decelerator and ISOLDE. At the end of his visit, he voiced his admiration for CERN and its personnel. As a renowned Nobel prize-winner Heinrich Rohrer has the opportunity to pass on his experience and enthusiasm to young scientists. During the evening meal, at which he met five young physicists and computer scientists, who were delighted with the chance to talk to him, he stressed the importance for re...

Cine club

CERN Multimedia

Cine club

2015-01-01

Wednesday 13 May 2015 at 20:00 CERN Council Chamber Read My Lips Directed by Jacques Audiard France, 2001, 105 minutes   Young secretary Carla is a long-time employee of a property development company. Loyal and hardworking, first to arrive and last to leave, Carla is beginning to chafe at the limitations of her career and is looking to move up. But as a 35-five-year-old woman with a hearing deficiency, she is not sure how to climb out of her humdrum life, though she is confident in her own abilities. Into her life comes Paul Angeli, a new trainee she decides to hire. Paul is 25 years old and completely unskilled, but Carla covers for him when the need arises because of his other qualities - he's a thief, fresh out of jail and very good-looking. It's a case of good meeting bad. Original version French; English subtitles   Wednesday 20 May 2015 at 20:00 CERN Council Chamber Imagine Directed by Andrzej Jakimowski Poland, 2012, 105 minutes Set in Lisbon, at an ...

„Dezynfekcja”. Literatura polska wobec eksterminacji osób psychicznie chorych

Directory of Open Access Journals (Sweden)

Arkadiusz Morawiec

2017-12-01

Full Text Available The article concerns the theme of extermination of the mentally ill and handicapped in Polish literature. It outlines the basic facts regarding this crime perpetrated by the Nazis and indicates how Polish literature reacted to it. There are few works which deal with this crime. Writers (and historians probably considered the extermination of the mentally ill to be a fact of insignificance compared to other Nazi crimes, or knew little about it. Thus Polish literature treats it incidentally, by entering it in another, more extensive or “more important” issue (the extermination of the Jews, the extermination of the Polish population, or treats it as an occasion to take up “more fundamental” (ideological problems. The article analyzes famous works, Stanisław Lem’s novel Hospital of the Transfiguration and Andrzej Bursa’s poem The liquidation of the mentally ill in Kobierzyn by the Germans, and less known texts: Piotr Matywiecki’s poem *** [Dragged into the sun….] and Anna Dziewit-Meller’s novel Mount Taygetus.

Around the Globe with Buzz Aldrin

CERN Multimedia

Katarina Anthony

2011-01-01

Buzz Aldrin! The news caused a sensation: his arrival was imminent. The man who, 40 years ago, first step foot on the moon, was to do the same at CERN.   Buzz Aldrin dumps the pilot beams from the LHC. Visiting the Globe on 1 March to endorse General Motors’ (GM) new ecological programme, Buzz Aldrin took advantage of the occasion to take a whistle-stop tour of the Organisation. “CERN is dealing with things going very fast underground; I’m dealing with things going fast – not that fast though! – up in orbit,” he said. Accompanied by his wife Lois and singer Katie Melua - also invited by GM to perform at the private event - Buzz began his visit with a short introduction to CERN at the Universe of Particles exhibit. He then met with Andrzej Siemko, group leader of the LHC machine protection, at the SM-18 super conducting magnet test facility. The astronaut’s last stop was at the CCC, where the LHC team had somethi...

The role of fluorescence diagnosis in clinical practice

Directory of Open Access Journals (Sweden)

Sieroń A

2013-07-01

Full Text Available Aleksander Sieroń,1 Karolina Sieroń-Stołtny,1 Aleksandra Kawczyk-Krupka,1 Wojciech Latos,1 Sebastian Kwiatek,1 Dariusz Straszak,1 Andrzej M Bugaj1,2 1Clinical Department of Internal Diseases, Angiology and Physical Medicine, Center for Laser Diagnostics and Therapy, Silesian Medical University, Bytom, 2College of Health, Beauty Care and Education, Poznan, Poland Abstract: Fluorescence diagnosis is a fast, easy, noninvasive, selective, and sensitive diagnostic tool for estimation of treatment results in oncology. In clinical practice the use of photodynamic diagnosis is focused on five targets: detection for prevention of malignant transformation precancerous changes, detection of neoplasmatic tissue in the early stages for fast removal, prevention of expansion and detection of recurrence of the cancer, monitoring therapy, and the possibility of excluding neoplasmatic disease. In this article, selected applications of fluorescence diagnosis at the Center for Laser Diagnostics and Therapy in Bytom, Poland, for each of these targets are presented. Keywords: autofluorescence, cancer, fluorescence, imaging, photodynamic diagnosis, photodynamic therapy 

Simulation of Electron Beam Trajectory of Thermionic Electron Gun Type with Pierce Electrode

International Nuclear Information System (INIS)

Suprapto; Djoko-SP; Djasiman

2000-01-01

The simulation of electron beam trajectory for electron gun of electron beam machine has been done. The simulation is carried out according to mechanical design of the electron gun. The simulation is carried out by using the software made by Andrzej Soltan Institute for Nuclear Studies, Swierk-Poland. The result obtained from simulation is approximately parallel electron beam trajectory of 20 mA beam current at 0.66 kV anode voltage, 15 mm cathode-anode distance and 67.5 o cathode angle. Arrangement of electron gun and accelerating tube with 15 kV voltage between anode and the first electrode of accelerating tube yields focus distance of 34 mm from the to cathode. To obtain the approximately parallel beam trajectory which has -0.03 o entrance angles to accelerating tube, the suitable cathode-anode voltage is 12.66 kV. With the entrance angle of -0.03 o it is expected that the electron beam can be accelerated and the beam profile has a small divergence after passing the accelerating tube. (author)

Taking care of you and care for others: an analysis of the activity of the work of technical and nursing assistants of a psychiatric institution for children and adolescents.

Science.gov (United States)

Mendes, Davidson Passos; Moraes, Geraldo Fabiano de Souza; Mendes, Juliana Cristina de Lima

2012-01-01

Our objective in this study, the analysis of potential fields of risk management in nursing work in psychiatric care to adolescents and children, while settings that go from the relationship between technical and organizational determinants of work activity and the skills of operators. It was established focus on the work process of the Technical and Nursing Assistants to seek for response elements in an attempt to understand the health-disease process experienced by these workers. It was used for analysis and data collection, through the method of Ergonomic Work Analysis (EWA), fifteen workers of nursing staff - T&NA, between effectives and contractors, and the strategies of action and regulation of these workers in relation to the interface that they deal with. The results show that the workers are exposed to all charges in an intense and specific way, causing physical and mental wear, as it approaches the psychological distress, exposure to the psychic pressure, not only through contact with the object of work, but the complexity of these relationships that are involved in nursing staff.

Essay and Ekphrasis (Herbert - Bieńkowska - Bieńczyk

Directory of Open Access Journals (Sweden)

Roma Sendyka

2009-01-01

Full Text Available Michel Riffaterre in article L'lllusion d'ekphrasis put forward an idea of "critical ekphrasis" (1994 what may become an invitation to ask if other sub-genres/modes of ekphrasis may be described. The text Essay and Ekphrasis develops this question in the field of essayistic traditions. Evoking the tendency of writing on art in that genre (from Montaigne, Diderot, Ruskin, Pater to art historians, critics and artists the article analyses three examples of ekphrases (by Zbigniew Herbert, Ewa Bieńkowska and Marek Bieńczyk to voice a hypothesis that ekphrasis in an essay may be a useful proof for those who question (ostensive representational powers of that textual tool. Essayistic ekphrasis seems to have a foremost referential character, pointing towards an object of art only to use it in order to describe cognitive procedures of the subject who in such a way (performatively and not overtly pictures himself mirroring his inner self in dispersed fragments of cultural object, dismantling the temporal and spatial difference between the viewer and the object in an illusion of an immediate presence.

How do users design? The case of sugar cane harvester machines.

Science.gov (United States)

Narimoto, Lidiane Regina; Camarotto, João Alberto

2017-01-01

Design in use and inventiveness are key concepts in ergonomics. It is well-known that users design but is not explored in the literature how they manage to do that. This paper aims to contribute to the discussion of how users actually design, by showing a research conducted in sugar cane harvesting in Brazil and in Australia. Through the methodology of the Ergonomic Work Analysis (EWA), the design modifications made by the harvesting teams were identified as well as their elaboration process. Three categories of modifications in machines' design were identified: structural, functional and operational and they were more numerous in Brazilian situations. It is proposed that two theories underlying the theme are intertwined: the instrument-mediated activity approach and the design as bricolage. It is argued that users design through the articulation of: a) the operators' activity, b) the mechanical technicians' inventory to practice bricolage as a way of designing and c) the work organisation and the existence of social spaces of interaction between these two subjects.

Annual Report 1999

International Nuclear Information System (INIS)

Chmielewska, D.; Infeld, E.; Preibisz, Z.; Zupranski, P.

2000-01-01

In the presented ''Annual Report 1999'' the scientific, organizational and educational activities of the Andrzej Soltan Institute for Nuclear Studies (SINS) are presented. The document is divided into two parts. First of them consists of the general information about management, scientific council, departments of SINS, scientific staff, visiting scientists, list of research project (grants) as well as information about PhD and DSc theses. The second one: ''Reports on Research'' describes the research activities of SINS. It is divided into 12 sections - in which the works of SINS departments and establishments are presented (Department of Nuclear Reactions, Department of Nuclear Spectroscopy and Technique, Department of Nuclear Electronics, Department of Radiation Shielding and Dosimetry, Department of Plasma Physics and Technology, Department of High Energy Physics, Department of Cosmic Radiation Physics, Department of Nuclear Theory, Department of Radiation Detectors, Department of Accelerator Physics and Technology, Department of Training and Consulting and Establishment for Nuclear Equipment). Each of these sections is preceded by short overview given by the head of given department. The foreword, in which the whole activities of the SINS are summarized, given by head of the Institute professor Z. Sujkowski is also given

Editorial.

Science.gov (United States)

Dudek, Dominika; Sobański, Jerzy A; Klasa, Katarzyna

2015-01-01

Dear Readers, In no time, we are almost halfway through 2015. Currently many issues concern psychiatrists, and does not fill them with optimism: an uncertain future implementation of the National Mental Health Protection Programme, or the recent amendment of criminal law, entering into force on 01.07.2015, on the significant enlargement of implementation of treatment and precautionary measures in psychiatric institutions. Prof. J.K. Gierowski [1] wrote in Psychiatria Polska about the misunderstanding and even conflict in this matter, between politicians, lawyers and psychiatric community, almost one and a half year ago. Several tragic, dramatic events (German Wings plane crash, the recent murder in Tworki) creates a bad social attitude towards the mentally ill. Our environment does not remain indifferent and is actively involved in the discussion - it is expressed by Letters to Editor, written by Elwira Marszałkowska-Krześ and Andrzej Brodziak, published in the current issue of the magazine. We are all aware of our responsibility - on the one hand for a safe environment for patients while ensuring adequate treatment to the ill, and on the other for creating the image of psychiatry and psychiatrists [2, 3]. (...).

Annual report 1997

Energy Technology Data Exchange (ETDEWEB)

Chmielewska, D.; Infeld, E.; Zupranski, P. [eds.

1998-12-31

In the presented ``Annual Report 1997`` the scientific, organizational end educational activities of the Andrzej Soltan Institute for Nuclear Studies (SINS) are presented. The document is divided into two parts. First of them consist of the general information about management, scientific council, department of SINS, scientific staff, visiting scientists, list of research project (grants), PhD and DSc theses as well as the information about organized schools and exhibitions. The second one: ``Reports on Research`` describes the research activities of SINS. It is divided into 12 parts - in which the works of SINS departments and establishments are presented (Department of Nuclear Reactions, Department of Nuclear Spectroscopy and Technique, Department of Nuclear Electronics, Department of Radiation Shielding and Dosimetry, Department of Plasma Physics and Technology, Department of High Energy Physics, Department of Cosmic Radiation Physics, Department of Atomic Nucleus Theory, Department of Radiation Detectors, Department of Accelerator Physics and Technology, Department of Training an Consulting and Establishment for Nuclear Equipment). Each of these parts are foreworded by short overview given by the head of appropriate department. The foreword, in which the whole activities of the SINS are summarized, given by head of the Institute professor Z. Sujkowski is also given

Annual Report 2001

International Nuclear Information System (INIS)

Chmielewska, D.; Infeld, E.; Preibisz, Z.; Zupranski, P.

2002-01-01

In the presented ''Annual Report 2001'' the scientific, organizational and educational activities of the Andrzej Soltan Institute for Nuclear Studies (SINS) are presented. The document is divided into two parts. First of them consists of the general information about management, scientific council, departments of SINS, scientific staff, visiting scientists, list of research project (grants) as well as information about PhD and DSc theses. The second one: ''Reports on Research'' describes the research activities of SINS. It is divided into 12 sections - in which the works of SINS departments and establishments are presented (Department of Nuclear Reactions, Department of Nuclear Spectroscopy and Technique, Department of Detectors and Nuclear Electronics, Department of Radiation Shielding and Dosimetry, Department of Plasma Physics and Technology, Department of High Energy Physics, Department of Cosmic Ray Physics, Department of Nuclear Theory, Department of Material Studies, Department of Accelerator Physics and Technology, Department of Training an Consulting and Establishment for Nuclear Equipment). Each of these sections are preceded by short overview given by the head of given department. The foreword, in which the whole activities of the SINS are summarized, given by head of the Institute professor Z. Sujkowski is also given

Annual Report 2000

Energy Technology Data Exchange (ETDEWEB)

Chmielewska, D; Infeld, E; Preibisz, Z; Zupranski, P [eds.

2001-07-01

In the presented ''Annual Report 2000'' the scientific, organizational end educational activities of the Andrzej Soltan Institute for Nuclear Studies (SINS) are presented. The document is divided into two parts. First of them consists of the general information about management, scientific council, department of SINS, scientific staff, visiting scientists, list of research projects (grants) as well as information about PhD and DSc theses. The second one: ''Reports on Research'' describes the research activities of SINS. It is divided into 12 sections - in which the works of SINS departments and establishments are presented (Department of Nuclear Reactions, Department of Nuclear Spectroscopy and Technique, Department of Detectors and Nuclear Electronics, Department of Radiation Shielding and Dosimetry, Department of Plasma Physics and Technology, Department of High Energy Physics, Department of Cosmic Ray Physics, Department of Nuclear Theory, Department of Material Studies, Department of Accelerator Physics and Technology, Department of Training an Consulting and Establishment for Nuclear Equipment). Each of these sections are preceded by short overview given by the head of given department. The foreword, in which the whole activities of the SINS are summarized, given by head of the Institute professor Z. Sujkowski is also given.

Annual report 1997

Energy Technology Data Exchange (ETDEWEB)

Chmielewska, D; Infeld, E; Zupranski, P [eds.

1999-12-31

In the presented ``Annual Report 1997`` the scientific, organizational end educational activities of the Andrzej Soltan Institute for Nuclear Studies (SINS) are presented. The document is divided into two parts. First of them consist of the general information about management, scientific council, department of SINS, scientific staff, visiting scientists, list of research project (grants), PhD and DSc theses as well as the information about organized schools and exhibitions. The second one: ``Reports on Research`` describes the research activities of SINS. It is divided into 12 parts - in which the works of SINS departments and establishments are presented (Department of Nuclear Reactions, Department of Nuclear Spectroscopy and Technique, Department of Nuclear Electronics, Department of Radiation Shielding and Dosimetry, Department of Plasma Physics and Technology, Department of High Energy Physics, Department of Cosmic Radiation Physics, Department of Atomic Nucleus Theory, Department of Radiation Detectors, Department of Accelerator Physics and Technology, Department of Training an Consulting and Establishment for Nuclear Equipment). Each of these parts are foreworded by short overview given by the head of appropriate department. The foreword, in which the whole activities of the SINS are summarized, given by head of the Institute professor Z. Sujkowski is also given

Annual Report 2002

Energy Technology Data Exchange (ETDEWEB)

Chmielewska, D; Infeld, E; Preibisz, Z; Zupranski, P [eds.

2003-07-01

In the presented ''Annual Report 2002'' the scientific, organizational end educational activities of the Andrzej Soltan Institute for Nuclear Studies (SINS) are presented. The document is divided into two parts. First of them consist of the general information about management, scientific council, departments of SINS, scientific staff, visiting scientists, list of research project (grants) as well as information about PhD and DSc theses. The second one: ''Reports on Research'' describes the research activities of SINS. It is divided into 12 sections - in which the works of SINS departments and establishments are presented (Department of Nuclear Reactions, Department of Nuclear Spectroscopy and Technique, Department of Detectors and Nuclear Electronics, Department of Radiation Shielding and Dosimetry, Department of Plasma Physics and Technology, Department of High Energy Physics, Department of Cosmic Ray Physics, Department of Nuclear Theory, Department of Material Studies, Department of Accelerator Physics and Technology, Department of Training an Consulting and Establishment for Nuclear Equipment). Each of these sections are preceded by short overview given by the head of given department. The foreword, in which the whole activities of the SINS are summarized, given by head of the Institute professor Z. Sujkowski is also given.

Annual report 1997

International Nuclear Information System (INIS)

Chmielewska, D.; Infeld, E.; Zupranski, P.

1998-01-01

In the presented ''Annual Report 1997'' the scientific, organizational end educational activities of the Andrzej Soltan Institute for Nuclear Studies (SINS) are presented. The document is divided into two parts. First of them consist of the general information about management, scientific council, department of SINS, scientific staff, visiting scientists, list of research project (grants), PhD and DSc theses as well as the information about organized schools and exhibitions. The second one: ''Reports on Research'' describes the research activities of SINS. It is divided into 12 parts - in which the works of SINS departments and establishments are presented (Department of Nuclear Reactions, Department of Nuclear Spectroscopy and Technique, Department of Nuclear Electronics, Department of Radiation Shielding and Dosimetry, Department of Plasma Physics and Technology, Department of High Energy Physics, Department of Cosmic Radiation Physics, Department of Atomic Nucleus Theory, Department of Radiation Detectors, Department of Accelerator Physics and Technology, Department of Training an Consulting and Establishment for Nuclear Equipment). Each of these parts are foreworded by short overview given by the head of appropriate department. The foreword, in which the whole activities of the SINS are summarized, given by head of the Institute professor Z. Sujkowski is also given

Annual Report 2002

International Nuclear Information System (INIS)

Chmielewska, D.; Infeld, E.; Preibisz, Z.; Zupranski, P.

2003-01-01

In the presented ''Annual Report 2002'' the scientific, organizational end educational activities of the Andrzej Soltan Institute for Nuclear Studies (SINS) are presented. The document is divided into two parts. First of them consist of the general information about management, scientific council, departments of SINS, scientific staff, visiting scientists, list of research project (grants) as well as information about PhD and DSc theses. The second one: ''Reports on Research'' describes the research activities of SINS. It is divided into 12 sections - in which the works of SINS departments and establishments are presented (Department of Nuclear Reactions, Department of Nuclear Spectroscopy and Technique, Department of Detectors and Nuclear Electronics, Department of Radiation Shielding and Dosimetry, Department of Plasma Physics and Technology, Department of High Energy Physics, Department of Cosmic Ray Physics, Department of Nuclear Theory, Department of Material Studies, Department of Accelerator Physics and Technology, Department of Training an Consulting and Establishment for Nuclear Equipment). Each of these sections are preceded by short overview given by the head of given department. The foreword, in which the whole activities of the SINS are summarized, given by head of the Institute professor Z. Sujkowski is also given

Annual Report 2000

International Nuclear Information System (INIS)

Chmielewska, D.; Infeld, E.; Preibisz, Z.; Zupranski, P.

2001-01-01

In the presented ''Annual Report 2000'' the scientific, organizational end educational activities of the Andrzej Soltan Institute for Nuclear Studies (SINS) are presented. The document is divided into two parts. First of them consists of the general information about management, scientific council, department of SINS, scientific staff, visiting scientists, list of research projects (grants) as well as information about PhD and DSc theses. The second one: ''Reports on Research'' describes the research activities of SINS. It is divided into 12 sections - in which the works of SINS departments and establishments are presented (Department of Nuclear Reactions, Department of Nuclear Spectroscopy and Technique, Department of Detectors and Nuclear Electronics, Department of Radiation Shielding and Dosimetry, Department of Plasma Physics and Technology, Department of High Energy Physics, Department of Cosmic Ray Physics, Department of Nuclear Theory, Department of Material Studies, Department of Accelerator Physics and Technology, Department of Training an Consulting and Establishment for Nuclear Equipment). Each of these sections are preceded by short overview given by the head of given department. The foreword, in which the whole activities of the SINS are summarized, given by head of the Institute professor Z. Sujkowski is also given

Annual Report 2004

Energy Technology Data Exchange (ETDEWEB)

Chmielewska, D; Infeld, E; Zupranski, P [eds.

2005-07-01

In the presented ''Annual Report 2004' the scientific, organizational and educational activities of the Andrzej Soltan Institute for Nuclear Studies (SINS) are presented. The document is divided into two parts. First of them consists of the general information about management, scientific council, departments of SINS, scientific staff, visiting scientists, list of research projects (grants) as well as information about PhD and DSc theses. The second one: ''Reports on Research'' describes the research activities of SINS. It is divided into 12 sections - in which the works of SINS departments and establishments are presented (Department of Nuclear Reactions, Department of Nuclear Spectroscopy and Technique, Department of Detectors and Nuclear Electronics, Department of Radiation Shielding and Dosimetry, Department of Plasma Physics and Technology, Department of High Energy Physics, Department of Cosmic Ray Physics, Department of Nuclear Theory, Department of Material Studies, Department of Accelerator Physics and Technology, Department of Training and Consulting and Establishment for Nuclear Equipment). Each of these sections are preceded by short overview given by the head of given department. The foreword, in which the whole activities of the SINS are summarized, given by head of the Institute professor Z. Sujkowski, is also given.

Annual Report 2004

International Nuclear Information System (INIS)

Chmielewska, D.; Infeld, E.; Zupranski, P.

2005-01-01

In the presented ''Annual Report 2004' the scientific, organizational and educational activities of the Andrzej Soltan Institute for Nuclear Studies (SINS) are presented. The document is divided into two parts. First of them consists of the general information about management, scientific council, departments of SINS, scientific staff, visiting scientists, list of research projects (grants) as well as information about PhD and DSc theses. The second one: ''Reports on Research'' describes the research activities of SINS. It is divided into 12 sections - in which the works of SINS departments and establishments are presented (Department of Nuclear Reactions, Department of Nuclear Spectroscopy and Technique, Department of Detectors and Nuclear Electronics, Department of Radiation Shielding and Dosimetry, Department of Plasma Physics and Technology, Department of High Energy Physics, Department of Cosmic Ray Physics, Department of Nuclear Theory, Department of Material Studies, Department of Accelerator Physics and Technology, Department of Training and Consulting and Establishment for Nuclear Equipment). Each of these sections are preceded by short overview given by the head of given department. The foreword, in which the whole activities of the SINS are summarized, given by head of the Institute professor Z. Sujkowski, is also given

Wstępna ocena ryzyka zawodowego fizjoterapeuty za pomocą metody SWP = Preliminary evaluation of occupational risk for physiotherapists using the SWP method

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Kinga Dorota Kulczycka

2016-09-01

  Wstępna ocena ryzyka zawodowego fizjoterapeuty za pomocą metody SWP Preliminary evaluation of occupational risk for physiotherapists using the SWP method   Kinga Kulczycka, Marcin Domagała, Ewa Stychno   Katedra i Zakład Zarządzania w  Pielęgniarstwie Wydział Nauk o  Zdrowiu Uniwersytet Medyczny w Lublinie Chair and Department of Management in Nursing Faculty Health Sciences Medical University of Lublin   Słowa kluczowe: Narażenie zawodowe, Fizjoterapeuci, Obciążenie pracą Key words: Occupational exposure, Physical therapists, Workload       Dr n. med. Kinga Kulczycka, mgr. Marcin Domagała, dr n.med. Ewa Stychno   Doctor of Medical Sciences Kinga Kulczycka, Holder of University Degree Marcin Domagała, Doctor of Medical Sciences Ewa Stychno     Streszczenie  Sposób wykonywania pracy, w warunkach znacznego obciążenia  ma wielkie znaczenie w profilaktyce zaburzeń układu mięśniowo-szkieletowego. Praca fizjoterapeutów często wiąże się z koniecznością przyjmowania niefizjologicznych  pozycji ciała, w trakcie których może dojść do urazów. Celem badania jest rozpoznanie pozycji ciała przyjmowanych przez fizjoterapeutów podczas pracy, które mogą stanowić  czynniki ryzyka związane ze  sposobem wykonywania pracy fizjoterapeuty. Materiał i metody  Badania przeprowadzono w 2014 r. z udziałem 100 fizjoterapeutów pracujących na oddziałach rehabilitacji, na terenie województwa Świętokrzyskiego. Wyniki Respondenci oceniali jako niewłaściwe przyjmowane  pozycje ciała, które zaobserwowali podczas wykonywania czynności zawodowych związane są z  pochylaniem podczas wykonywania czynności,  zgięcie odcinka lędźwiowego kręgosłupa i częste rotacje. Jako dodatkowe obciążenia w pracy uważali zginanie głowy do przodu lub skręcenie karku. Ruchy ramion stanowią znaczną uciążliwość dla fizjoterapeutów i występują podczas podnoszenia rąk do przodu i przesuwaniu ich w kierunku klatki piersiowej

Annual Report 2003

International Nuclear Information System (INIS)

Chmielewska, D.; Infeld, E.; Preibisz, Z.; Zupranski, P.

2004-01-01

In the presented ''Annual Report 2003'' the scientific, organizational end educational activities of the Andrzej Soltan Institute for Nuclear Studies (SINS) are presented. The document is divided into two parts. First of them consists of the general information about management, scientific council, departments of SINS, scientific staff, visiting scientists, list of research project (grants) as well as information about PhD and DSc theses and the organized by SINS conferences and workshops. The second one: ''Reports on Research'' describes the research activities of SINS. It is divided into 12 sections - in which the works of SINS departments and establishments are presented (Department of Nuclear Reactions, Department of Nuclear Spectroscopy and Technique, Department of Detectors and Nuclear Electronics, Department of Radiation Shielding and Dosimetry, Department of Plasma Physics and Technology, Department of High Energy Physics, Department of Cosmic Ray Physics, Department of Nuclear Theory, Department of Material Studies, Department of Accelerator Physics and Technology, Department of Training and Consulting and Establishment for Nuclear Equipment). Each of these sections are preceded by short overview given by the head of given department. The foreword, in which the whole activities of the SINS are summarized, given by head of the Institute professor Z. Sujkowski is also given

Annual Report 1998

Energy Technology Data Exchange (ETDEWEB)

Chmielewska, D; Infeld, E; Preibisz, Z; Zupranski, P [eds.

1999-10-01

In the presented ``Annual Report 1998`` the scientific, organizational and educational activities of the Andrzej Soltan Institute for Nuclear Studies (SINS) are presented. The document is divided into two parts. First of them consists of the general information about management, scientific council, department of SINS, scientific staff, visiting scientists, list of research project (grants), PhD and DSc theses as well as the information about organized schools and exhibitions. The second one: ``Reports on Research`` describes the research activities of SINS. It is divided into 12 parts - in which the works of SINS departments and establishments are presented (Department of Nuclear Reactions, Department of Nuclear Spectroscopy and Technique, Department of Nuclear Electronics, Department of Radiation Shielding and Dosimetry, Department of Plasma Physics and Technology, Department of High Energy Physics, Department of Cosmic Radiation Physics, Department of Nuclear Theory, Department of Radiation Detectors, Department of Accelerator Physics and Technology, Department of Training an Consulting and Establishment for Nuclear Equipment). Each of these parts are preceded by a short overview given by the head of the given department. The foreword, in which the whole activities of the SINS are summarized, given by head of the Institute professor Z. Sujkowski is also given

Annual Report 1998

International Nuclear Information System (INIS)

Chmielewska, D.; Infeld, E.; Preibisz, Z.; Zupranski, P.

1999-01-01

In the presented ''Annual Report 1998'' the scientific, organizational and educational activities of the Andrzej Soltan Institute for Nuclear Studies (SINS) are presented. The document is divided into two parts. First of them consists of the general information about management, scientific council, department of SINS, scientific staff, visiting scientists, list of research project (grants), PhD and DSc theses as well as the information about organized schools and exhibitions. The second one: ''Reports on Research'' describes the research activities of SINS. It is divided into 12 parts - in which the works of SINS departments and establishments are presented (Department of Nuclear Reactions, Department of Nuclear Spectroscopy and Technique, Department of Nuclear Electronics, Department of Radiation Shielding and Dosimetry, Department of Plasma Physics and Technology, Department of High Energy Physics, Department of Cosmic Radiation Physics, Department of Nuclear Theory, Department of Radiation Detectors, Department of Accelerator Physics and Technology, Department of Training an Consulting and Establishment for Nuclear Equipment). Each of these parts are preceded by a short overview given by the head of the given department. The foreword, in which the whole activities of the SINS are summarized, given by head of the Institute professor Z. Sujkowski is also given

Annual Report 2003

Energy Technology Data Exchange (ETDEWEB)

Chmielewska, D; Infeld, E; Preibisz, Z; Zupranski, P [eds.

2004-07-01

In the presented ''Annual Report 2003'' the scientific, organizational end educational activities of the Andrzej Soltan Institute for Nuclear Studies (SINS) are presented. The document is divided into two parts. First of them consists of the general information about management, scientific council, departments of SINS, scientific staff, visiting scientists, list of research project (grants) as well as information about PhD and DSc theses and the organized by SINS conferences and workshops. The second one: ''Reports on Research'' describes the research activities of SINS. It is divided into 12 sections - in which the works of SINS departments and establishments are presented (Department of Nuclear Reactions, Department of Nuclear Spectroscopy and Technique, Department of Detectors and Nuclear Electronics, Department of Radiation Shielding and Dosimetry, Department of Plasma Physics and Technology, Department of High Energy Physics, Department of Cosmic Ray Physics, Department of Nuclear Theory, Department of Material Studies, Department of Accelerator Physics and Technology, Department of Training and Consulting and Establishment for Nuclear Equipment). Each of these sections are preceded by short overview given by the head of given department. The foreword, in which the whole activities of the SINS are summarized, given by head of the Institute professor Z. Sujkowski is also given.

Summary of my experiences as an undergraduate researcher in the U.S. and as a Fulbright Student Researcher at the Institute of Immunology and Experimental Therapy in Poland

Directory of Open Access Journals (Sweden)

Zelasko Susan

2016-05-01

Full Text Available Over the course of my undergraduate studies in Molecular and Cellular Biology and the experiences following my graduation, I became increasingly interested in research that can directly improve patient care. My research experiences in the U.S. include studying cytochrome P450 enzymes in Nanodiscs at the University of Illinois Urbana-Champaign and examining immune evasion by acute lymphoblastic leukemia cells at the University of Colorado Cancer Center. Beyond work in the laboratory, I also participated in a year-long project to implement a water delivery system in Honduras, leading to my interest in infectious disease research. My interest in this field grew after learning about phage therapy, a way of treating antibiotic-resistant infections, during an honors virology seminar. Only a few research groups are dedicated to studying phage therapy, which includes the Institute of Immunology and Experimental Therapy (IIET in Poland. I was fortunate enough to receive a U.S. Fulbright research grant to study the immune response to phage therapy under the mentorship of Prof. hab. n. med. Andrzej Górski at the IIET. In this article, I will discuss my involvement at U.S. and European institutions, the insights I have gained, and how other students can similarly get involved in research.

PREFACE: MicroTherm' 2013 - Microtechnology and Thermal Problems in Electronics

Science.gov (United States)

Lisik, Zbigniew; Raj, Ewa

2014-04-01

MicroTherm is an International Conference on Microtechnology and Thermal Problems in Electronics organised as a cyclic event since 1996. The success of the first seminar, which was devoted mainly to thermal management aspects, and the successive conferences have led us to the tenth edition. Since the first meeting, the scope of the conference has expanded, following the progress of electronics. Now, it covers subjects connected with extreme temperature, electronics, sensors and measurement techniques, modelling, simulation, wide band-gap materials, packaging and reliability, renewable energy sources and photonics with special emphasis on microelectronic technologies. MicroTherm' 2013 was held in Lodz, Poland, on 25-28 June 2013. The programme consistied of invited talks and nine regular sessions in the form of planar discussions and poster presentations, including a Students' Session. The Students' session gave an opportunity for students and young researchers to present their first achievements in the field of science. The next MicroTherm Conference is going to be held on 22-25 June 2015, in Lodz — a beautiful, post-industrial city located in the centre of Poland. Please, feel invited to MicroTherm' 2015 (www.microtherm.dsod.pl). Ewa Raj and Zbigniew Lisik Editors

Entropy-Weighted Instance Matching Between Different Sourcing Points of Interest

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Lin Li

2016-01-01

Full Text Available The crucial problem for integrating geospatial data is finding the corresponding objects (the counterpart from different sources. Most current studies focus on object matching with individual attributes such as spatial, name, or other attributes, which avoids the difficulty of integrating those attributes, but at the cost of an ineffective matching. In this study, we propose an approach for matching instances by integrating heterogeneous attributes with the allocation of suitable attribute weights via information entropy. First, a normalized similarity formula is developed, which can simplify the calculation of spatial attribute similarity. Second, sound-based and word segmentation-based methods are adopted to eliminate the semantic ambiguity when there is a lack of a normative coding standard in geospatial data to express the name attribute. Third, category mapping is established to address the heterogeneity among different classifications. Finally, to address the non-linear characteristic of attribute similarity, the weights of the attributes are calculated by the entropy of the attributes. Experiments demonstrate that the Entropy-Weighted Approach (EWA has good performance both in terms of precision and recall for instance matching from different data sets.

Heavy physical work under time pressure: the garbage collection service--a case study.

Science.gov (United States)

Camada, Ilza Mitsuko de Oliveira; Pataro, Silvana Maria Santos; Fernandes, Rita de Cássia Pereira

2012-01-01

The increased generation of garbage has become a problem in large cities, with greater demand for collection services. The collector is subjected to high workload. This study describes the work in garbage collection service, highlighting the requirements of time, resulting in physical and psychosocial demands to collectors. Ergonomic Work Analysis (EWA) - a method focused on the study of work in real situations was used. Initially, technical visits, global observations and unstructured interviews with different subjects of a garbage collection company were conducted. The following step of the systematic observations was accompanied by interviews conducted during the execution of tasks, inquiring about the actions taken, and also interviews about the actions, but conducted after the development of the tasks, photographic records and audiovisual recordings, of workers from two garbage collection teams. Contradictions between the prescribed work and activities (actual work) were identified, as well as the variability present in this process, and strategies adopted by these workers to regulate the workload. It was concluded that the insufficiency of means and the organizational structure of management ensue a situation where the collection process is maintained at the expense of hyper-requesting these workers, both physically and psychosocially.

Working aspects and musculoskeletal disorders of workers in a school’s lactary

Directory of Open Access Journals (Sweden)

Maria do Carmo Baracho de Alencar

2017-03-01

Full Text Available Objective: To investigate the working conditions and the occurrence of musculoskeletal disorders in cooks from a Primary Public School. Method: This is an ergonomic study and a case study. General data about the school and the workplace were surveyed. A questionnaire was applied to cooks to collect information on personal and work aspects and musculoskeletal symptoms. Tasks and work processes, systematic observations and records of work activities were noted in paper, as based on the methodological approach of Ergonomic Work Analysis (EWA. Results: Two cooks participated in the study. They were 43 and 49 years old. They reported musculoskeletal symptoms in the region of wrist, hands, and low back in the last 12 months; and in the cervical and low back in the last seven days. Several inappropriate working conditions were found, including some related to the physical space and thermal environment, as well as aspects of work organization (undersized team, time for delivery of foods, etc.. Conclusion: Precarious working conditions tend to favor the emergence and/or worsening of musculoskeletal disorders in cooks of Primary Public Schools, and further research aimed at prevention and health promotion are necessary

ERGONOMIC WORK ANALYSIS APPLICATION IN A SMALL SHOE BUSINESS

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Aline Marian Callegaro

2013-11-01

Full Text Available This paper aims to presentthe results after conducting an Ergonomic Work Analysis (EWA in a smallbusiness located in Porto Alegre. The ergonomic intervention was performed basedon Guérin et al. (2001 and aimed to analyze the process organization and thelayout of the shoemaker workstations to provide improvements to these areas.The starting point was the account of the small shoe business owner’s need hadto hire one more shoemaker without increasing the company physical space. The EWAwas used focusing the work organization, how the flow of information ran fromthe entry of an order to the final stage of the product repairing. Thediagnosis showed the company main problems were related to the shop assistantsdependence on the shoemakers to provide budget information and delivery time tocustomers and the layout organization. Among the results, a temporal analysisof two company recurrent tasks was performed in order to ascertain possiblelosses related to the displacement and the search for material. A new layoutscheme was also proposed, aiming to organize the work stations, making easierthe stock, tools and equipment removal, providing a free space to make possiblethe hiring of the new shoemakers within the current company boundaries.

Fractionation of hairless canary seed (Phalaris canariensis) into starch, protein, and oil.

Science.gov (United States)

Abdel-Aal, El-Sayed M; Hucl, Pierre; Patterson, Carol Ann; Gray, Danielle

2010-06-09

Canary seed is an important specialty crop in Canada. The current market for this true cereal (i.e., belonging to the family Poaceae as wheat) is limited to feed for caged birds. However, canary seed holds a promise for many food and industrial applications based on its composition. Three wet milling procedures based on ethanol (E), water (W), and alkaline (A) extractions used in different order were investigated to determine extraction efficiency and purity of starch, protein, oil, and fiber separated from hairless canary seed, a variety developed for human consumption. Highest extraction efficiencies were obtained when canary seed was defatted with ethanol and then extracted with alkali and water (EAW process). Using this process, approximately 92% pure starch, 75% pure protein, and oil were recovered from canary seed groats. The highest purity of protein, however, was obtained when canary seed was fractionated by the EWA process, that is, defatted and then extracted with water followed by alkali. Fiber component separated prior to alkaline extraction contained high amounts of nonfiber components as indicated by its yield. The EAW extraction process seems to be more promising in canary seed fractionation based on recovery and purity of components.

Ergonomic activity analysis of the musicians of the Symphony Orchestra of Paraná state: risk factors and workloads

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Jaqueline de Lima

2014-04-01

Full Text Available This study aimed to investigate the risk factors present in the work activity and their impact on the health of the musicians of the Symphony Orchestra of Parana state. It is a descriptive qualitative research based on the method of Ergonomic Workplace Analysis of Francophone strand, used as a tool by occupational therapists in the health-work interface. The following procedures were performed: bibliographical survey, documental analysis of productivity data, production and quality of the task, systematic observation of the rehearsals of the Symphony Orchestra of Parana, task and workplace analysis with the application of Ergonomic Workplace Analysis (EWA and, confrontation of the data analyzed with an instrumental musician. As a result, the study showed significant deviations with reference to the standards described in Brazilian Norm 17 (Ergonomics, especially regarding individual cognitive and physical demands as well as demands related to work organization, considering each item evaluated by this analytical instrument. The action of occupational therapy was grounded on the insertion in the health and illness process, health promotion, illness prevention, and training of musicians as workers and social actors, envisioning the transformation of work situations.

The Role of Field Classes in Education of Prospective Teachers in Biology

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E. Fleszar

2009-12-01

Full Text Available Field classes are indispensable in education of biology and environment protection students, as they allow a future teacher to carry out teaching material bringing together theory and practice through activity. In the framework of Biology Didactics classes the biology students of the Faculty of Natural Sciences at the University of Szczecin participate actively in the works on didactic nature trail in the Arkoñski Woods prepared by Dr. Ewa Fleszar. During the work on didactic natural path the students make themselves acquainted with: field class objectives; field class tasks; field class programmes, e.g. concerning phenology; flora and fauna species. Writing synopsis of field classes for selected lesson units at different teaching levels they acquire sound knowledge based on the ecological contents. Contacts with nature as well as gaining the experience during field classes allow them to obtain competences for working in the field and to understand the objectives of carrying out such classes. Field classes have an effect on developing interests of participants in the subject, and affect the improvement of teaching performance. Visit to the field forms ecological awareness, which leads to obtaining an ecological culture.

Cloud amount/frequency, NITRATE and other data from EWA, BORA and other platforms from 1928-08-16 to 1985-12-17 (NODC Accession 9300135)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The Ocean Serial data in this accession was collected by Poland as part of Global Ocean Data Archeaology and Rescue (GODAR) project using over 14 ships. The data was...

Committees and organizers

Science.gov (United States)

2011-07-01

Chairman:Jozef Spałek (Kraków) Program Committee:Stephen Blundell (Oxford), J Michael D Coey (Dublin), Dominique Givord (Grenoble), Dariusz Kaczorowski (Wrocław), Roman Micnas (Poznań), Marek Przybylski (Halle), Ludiwig Schultz (Dresden), Vladimir Sechovsky (Prague), Jozef Spałek (Kraków), Henryk Szymczak (Warszawa), Manuel Vázquez (Madrid) Publication Committee:Dariusz Kaczorowski, Robert Podsiadły, Jozef Spałek, Henryk Szymczak, Andrzej Szytuła Local committee:Maria Bałanda, Anna Majcher, Robert Podsiadły, Michał Rams, Andrzej Ślebarski, Krzysztof Tomala Editors of the Proceedings:Jozef Spałek, Krzysztof Tomala, Danuta Goc-Jagło, Robert Podsiadły, Michał Rams, Anna Majcher Plenary, semi-plenary and tutorial speakers:Ernst Bauer (Wien)Stephen Blundell (Oxford)J Michael D Coey (Dublin)Russell P Cowburn (London)Burkard Hillebrands (Kaiserslautern)Claudine Lacroix (Grenoble)Lluís Mañosa (Barcelona)María del Carmen Muñoz (Madrid)Bernard Raveau (Caen)Pedro Schlottmann (Tallahassee)Frank Steglich (Dresden)Oliver Waldmann (Freiburg) Invited speakers within symposia: R Ahuja (Uppsala)A Kirilyuk (Nijmegen) M Albrecht (Vienna)L Theil Kuhn (Roskilde) K Bärner (Göttingen)J Liu (Dresden) U Bovensiepen (Duisburg)G Lorusso (Modena) V Buchelnikov (Chelyabinsk)M M Maska (Katowice) B Chevalier (Bordeaux)Y Mukovskii (Moscow) O Chubykalo-Fesenko (Madrid)M Pannetier-Lecoeur (Saclay) A V Chumak (Kaiserslautern)G Papavassiliou (Athens) J M D Coey (Dublin)K R Pirota (Campinas) B Dabrowski (DeKalb)P Przyslupski (Warszawa) S Das (Aveiro)M Reiffers (Košice) A del Moral (Zaragoza)K Sandeman (London) V E Demidov (Muenster)D Sander (Halle) B Djafari-Rouhani (Lille)M Sawicki (Sendai/Warsaw) H A Dürr (Menlo Park)J Schaefer (Würzburg) J Fassbender (Dresden)H Schmidt (Wetzikon) J Fontcuberta (Barcelona)J Spałek (Kraków) V Garcia (Orsay)L Straka (Helsinki) J N Gonçalves (Aveiro)A Szewczyk (Warszawa) M E Gruner (Duisburg)Y Taguchi (Wako) G Gubbiotti (Perugia)A Thiaville

Danton. Wektory interpretacji filmu Andrzeja Wajdy

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Włodzimierz Szturc

2017-12-01

Full Text Available In this paper, the author presents the final period of the French Revolution as interpretated by Andrzej Wajda. The screenplay was prepared by Jean-Claude Carrière based on Stanisława Przybyszewska’s drama (also used by Wajda as a screenplay in many dramas. It helped the director to describe the reality of the intense time of Robespierre’s terror and Jacobin efforts to guillotine Danton and his allies. Wajda reveals the same mechanisms of crime, manipulation and lies which became the backdrop for political events in Poland between 1981-1983 (especially with the introduction of martial law in Poland in 1981. The model of Danton’s fall and the strengthening of totalitarian rule are considered the current model of history, which is based on cruelty and the struggle for power. The film forms the basis for a broader view of history as the tragic entanglement of events, which is the result of hubris and the desire for material goods, and is the origin of totalitarian rule. References to the emblems of the revolution, allegories, and the symbolism of art (paintings of David are the fundamental ekphrasis of meanings set by the film. Wajda’s analysis of Danton shows some typical ways of understanding and interpreting the signs of culture and history.

„W ogóle jestem niechętny dźwiękom”. Muzyka w filmie Tatarak Andrzeja Wajdy

Directory of Open Access Journals (Sweden)

Anna Al-Araj

2017-12-01

Full Text Available The aim of this article is to interpret the musical layer of Andrzej Wajda’s 2009 movie Tatarak (Sweet Rush, based on the novel by Jarosław Iwaszkiewicz. In the first part, the author attempts to depict the complex relationship between the literary and film works of these two artists and emphasizes three main motifs used by both of them: love and death, water and women’s themes. Next, Wajda’s attitude to music is analyzed. He treats sounds as an element of everyday life and, as is typical for our times, he is aware of the “dissolution” of musical works. In the next part, the author articulates the main problems of Sweet Rush, drawing attention to both Iwaszkiewicz’s novel and Wajda’s movie. The director’s adaptation, which is full of intermedia references, revolves around the theme of death and seems to underestimate the sexual aspect of Iwaszkiewicz’s work. Finally, Pawel Mykietyn’s soundtrack to Sweet Rush is interpreted. The composer used one of his earlier Shakespeare’s Sonnets (2000, which plays the role of a leitmotif, to illustrate the most enigmatic, inexplicable scenes from Wajda’s movie. Thanks to its discrete, sparing and “austere” nature, Mykietyn’s music made the artistic composition of Sweet Rush more balanced and revealed the suggestiveness of this work.

Ergonomics and risk management in high risk organizations: nuclear power plant operator decision making; A ergonomia e a gestao de risco em organizacoes que lidam com tecnologias perigosas: tomada de decisao de operadores de usinas nucleares

Energy Technology Data Exchange (ETDEWEB)

Carvalho, Paulo Victor Rodrigues de

2003-08-15

Nuclear power plants are high hazard environments where emergency situations can have devastating effects. The operator crew has the ultimate responsibility to control the energy production process with safety. The outcome of a crisis is consequently dependent on the crew's judgement, decision making and situation awareness. In such way we should know how operators make their decisions in order to develop safety strategies. The aim of this thesis is to examine the cognitive processes through which operators make decisions when dealing with micro incidents during their actual work, and to determine whether they use a naturalistic or normative decision making strategy. That is, do they try to recognize the micro incident as familiar and base decisions on condition-action rules (naturalistic), or do they need to concurrently compare and contrast options before selecting the best possible (normative). The method employed for data collection was the Cognitive Task Analysis (CTA) and Ergonomic Work Analysis (EWA). The main findings of this thesis were that decision making is primarily based on naturalistic strategies, such as condition-action rules and recognition. In new situations rules are created ad hoc. These rules appear derived from experience and training rather than from Standard Operating Procedures and contrast normative competence standards used by nuclear industry. (author)

Epigenetics and cerebral organoids: promising directions in autism spectrum disorders.

Science.gov (United States)

Forsberg, Sheena Louise; Ilieva, Mirolyuba; Maria Michel, Tanja

2018-01-10

Autism spectrum disorders (ASD) affect 1 in 68 children in the US according to the Centers for Disease Control and Prevention (CDC). It is characterized by impairments in social interactions and communication, restrictive and repetitive patterns of behaviors, and interests. Owing to disease complexity, only a limited number of treatment options are available mainly for children that alleviate but do not cure the debilitating symptoms. Studies confirm a genetic link, but environmental factors, such as medications, toxins, and maternal infection during pregnancy, as well as birth complications also play a role. Some studies indicate a set of candidate genes with different DNA methylation profiles in ASD compared to healthy individuals. Thus epigenetic alterations could help bridging the gene-environment gap in deciphering the underlying neurobiology of autism. However, epigenome-wide association studies (EWAS) have mainly included a very limited number of postmortem brain samples. Hence, cellular models mimicking brain development in vitro will be of great importance to study the critical epigenetic alterations and when they might happen. This review will give an overview of the state of the art concerning knowledge on epigenetic changes in autism and how new, cutting edge expertise based on three-dimensional (3D) stem cell technology models (brain organoids) can contribute in elucidating the multiple aspects of disease mechanisms.

Ergonomics and risk management in high risk organizations: nuclear power plant operator decision making

International Nuclear Information System (INIS)

Carvalho, Paulo Victor Rodrigues de

2003-08-01

Nuclear power plants are high hazard environments where emergency situations can have devastating effects. The operator crew has the ultimate responsibility to control the energy production process with safety. The outcome of a crisis is consequently dependent on the crew's judgement, decision making and situation awareness. In such way we should know how operators make their decisions in order to develop safety strategies. The aim of this thesis is to examine the cognitive processes through which operators make decisions when dealing with micro incidents during their actual work, and to determine whether they use a naturalistic or normative decision making strategy. That is, do they try to recognize the micro incident as familiar and base decisions on condition-action rules (naturalistic), or do they need to concurrently compare and contrast options before selecting the best possible (normative). The method employed for data collection was the Cognitive Task Analysis (CTA) and Ergonomic Work Analysis (EWA). The main findings of this thesis were that decision making is primarily based on naturalistic strategies, such as condition-action rules and recognition. In new situations rules are created ad hoc. These rules appear derived from experience and training rather than from Standard Operating Procedures and contrast normative competence standards used by nuclear industry. (author)

Determination of copper in biological materials by neutron activation analysis using short-lived 66Cu

International Nuclear Information System (INIS)

Dybczynski, R.; Danko, B.; Kaczorowski, J.

1989-01-01

A method for determination of copper traces in biological materials based on neutron activation employing 65 Cu(n, γ) 66 Cu reaction and preconcentration by extraction chromatography has been devised. The 200-500 mg samples after wet digestion and evaporation were dissolved in glycine solution and after pH adjusting to ca. 4.4 were passed through the column with Lix 64N on Bio Beads SM-1 for isolation of copper traces from the matrix elements. Other cations were selectively eluted with 0.1 mol x 1 -1 (glycine-HNO 3 ) buffer, 1 mol x 1 -1 in NH 4 NO 3 (pH = 3.6). The resin bed with quantitatively retained copper was sealed in the PE bag and irradiated together with Cu standards in EWA reactor using pneumatic tube facility. The activity of the short-lived 66 Cu was measured in samples and standard by gamma-ray spectrometry with Ge(Li) detector. Good accuracy of the method was confirmed by analysis of the following certified reference materials: NBS 1571 Orchad leaves, IAEA H-4 Animal muscle, IAEA V-8 Rye flour, IAEA A-11 milk powder. The detection limit amounted to 0.34 mg/kg, for the sample weight of 500 mg. (author)

Introducing RiskSOAP to communicate the distributed situation awareness of a system about safety issues: an application to a robotic system.

Science.gov (United States)

Chatzimichailidou, Maria Mikela; Dokas, Ioannis M

2016-03-01

This paper introduces the RiskSOAP ('RiskSOAP' is the abbreviation for Risk SituatiOn Awareness Provision.) indicator to measure the capability of a complex socio-technical system to provide its agents with situation awareness (SA) about the presence of its threats and vulnerabilities and enables analysts to assess distributed SA. The RiskSOAP methodology adopts a comparative approach between two design versions of a system differing in the elements and characteristics that can enhance or cause the degradation of the awareness provision capability. The methodology uniquely combines three methods: (1) the STPA hazard analysis, (2) the EWaSAP early warning sign identification approach, and (3) a dissimilarity measure for calculating the distance between binary sets. In this paper, the RiskSOAP methodology was applied to a robotic system and the findings show that the indicator is an objective measure for the system's capability to provide its agents with SA about its threats and vulnerabilities. Practitioner Summary: This paper suggests a novel methodology for assessing distributed situation awareness (DSA) regarding safety issues. Given that systems consist of specifications and components possible to be mapped, the risk SA provision capability (RiskSOAP) methodology demonstrates the feasibility of measuring to what extent systems' elements contribute to the emergence of DSA.

Nanoparticles of carbon allotropes inhibit glioblastoma multiforme angiogenesis in ovo

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Grodzik M

2011-11-01

Full Text Available Marta Grodzik1, Ewa Sawosz1, Mateusz Wierzbicki1, Piotr Orlowski1, Anna Hotowy2, Tomasz Niemiec1, Maciej Szmidt3, Katarzyna Mitura4, André Chwalibog21Division of Biotechnology and Biochemistry of Nutrition, Warsaw University of Life Sciences, Warsaw, Poland; 2Department of Basic Animal and Veterinary Science, University of Copenhagen, Copenhagen, Denmark; 3Division of Histology and Embryology, Warsaw University of Life Sciences, Warsaw, Poland; 4Department of Biomedical Engineering, Koszalin University of Technology, Koszalin, PolandAbstract: The objective of the study was to determine the effect of carbon nanoparticles produced by different methods on the growth of brain tumor and the development of blood vessels. Glioblastoma multiforme cells were cultured on the chorioallantoic membrane of chicken embryo and after 7 days of incubation, were treated with carbon nanoparticles administered in ovo to the tumor. Both types of nanoparticles significantly decreased tumor mass and volume, and vessel area. Quantitative real-time polymerase chain reaction analysis showed downregulated fibroblast growth factor-2 and vascular endothelial growth factor expression at the messenger ribonucleic acid level. The present results demonstrate antiangiogenic activity of carbon nanoparticles, making them potential factors for anticancer therapy.Keywords: cancer, nanoparticle, embryo, angiogenesis, FGF-2, VEGF

Ergophthalmology in accounting offices: the computer vision syndrome (CVS

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Arjuna Nudi Perin

Full Text Available Abstract Purpose: This study aimed to determine the presence of the symptoms of computer vision syndrome (CVS accounting office employees. Methods: The research tools used were a questionnaire based on the set of symptoms of CVS rated by Likert scale (1-5 and workplace observations based on Ergonomic Workplace Analysis (EWA. Results: The participants who worked with a viewing angle of less than 10º relative to the screen had more symptoms, particularly of pain in the back of the neck and back (p = 0.0460. The participants who used lighting other than 450 and 699 lux reported significant headache (p = 0.0045 and dry eye (p = 0.0329 symptoms. Younger workers had more headaches (p = 0.0182, and workers with fewer years of employment had more headaches and dry eyes symptoms (p = 0.0164 and p = 0.0479, respectively. A total of 37% of the participants reported a lack of guidance regarding prevention and painful symptoms in the back of the neck and back (p = 0.0936. Conclusion: Younger participants with fewer years of employment, who had not received information regarding proper computer use, who did not use lighting between 450 and 699 lux or who worked with viewing angles of less than 10º had more computer vision syndrome symptoms.

Odzyskać liberalizm. Recenzja książki Andrzeja Walickiego "Od projektu komunistycznego do neoliberalnej utopii", Warszawa: Universitas 2013

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Małgorzata Fidelis

2016-01-01

Full Text Available To Recover Liberalism. Review of a book by Andrzej Walicki Od projektu komunistycznego do neoliberalnej utopii (From the Communist Project to the Neoliberal Utopia, Warszawa: Universitas 2013 This review discusses a recent book by Andrzej Walicki, Od projektu komunistycznego do neoliberalnej utopii (From the Communist Project to the Neoliberal Utopia (Warszawa: Universitas 2013. The book features a collection of essays, interviews, and scholarly articles published by Walicki in academic and popular journals between 2001 and 2012. Topics include a history of the communist project in a broader European perspective; the significance and legacy of de-Stalinization in Poland, with a particular emphasis on what the author calls "the Polish road away from communism" after 1956; right-wing conservative politics in Poland after 1989, the politicization of the memory of communism; and possible directions for the development of the Polish Left as a necessary component of a healthy democratic system. The compelling scholarly discussion is often combined with autobiographical sketches of an intellectual who has been deeply engaged in intellectual and social life in postwar Poland. Walicki, a prominent intellectual and specialist on intellectual history, studied and worked in Warsaw until he emigrated to Australia and then the United States (The University of Notre Dame in the 1980s. In that sense, Walicki provides a unique perspective on Polish history and culture, influenced by both Polish and American academic worlds and intellectual traditions. The strength of the book is its focus on the role of language and the manipulation of terms such as "communism" or "liberalism" by contemporary political leaders in Poland to achieve specific emotional reactions from the public. One of the central claims of the book is that Polish political elites have "distorted" the meaning of liberalism by connecting it solely to the free market rather than to

Radiotherapy combined with hormonal therapy in prostate cancer: the state of the art

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Piotr Milecki

2010-10-01

Full Text Available Piotr Milecki1,2, Piotr Martenka1, Andrzej Antczak3, Zbigniew Kwias31Department of Radiotherapy, Greater Poland Cancer Center, Poznan, Poland; 2Department of Electroradiology, Medical University, Poznan, Poland; 3Chair of Urology, Medical University, Poznan, PolandAbstract: Androgen-deprivation therapy (ADT is used routinely in combination with definitive external beam radiation therapy (EBRT in patients with high-risk clinically localized or locally advanced disease. The combined treatment (ADT–EBRT also seems to play a significant role in improving treatment results in the intermediate-risk group of prostate cancer patients. On the other hand, there is a growing body of evidence that treatment with ADT can be associated with serious and lifelong adverse events including osteoporosis, cardiovascular disease, diabetes, and many others. Almost all ADT adverse events are time dependant and tend to increase in severity with prolongation of hormonal manipulation. Therefore, it is crucial to clearly state the optimal schedule for ADT in combination with EBRT, that maintaining the positive effect on treatment efficacy would keep the adverse events risk at reasonable level. To achieve this goal, treatment schedule may have to be highly individualized on the basis of the patient-specific potential vulnerability to adverse events. In this study, the concise and evidence-based review of current literature concerning the general rationales for combining radiotherapy and hormonal therapy, its mechanism, treatment results, and toxicity profile is presented.Keywords: prostate cancer, radiotherapy, androgen deprivation, combined treatment

High-throughput DNA methylation analysis in anorexia nervosa confirms TNXB hypermethylation.

Science.gov (United States)

Kesselmeier, Miriam; Pütter, Carolin; Volckmar, Anna-Lena; Baurecht, Hansjörg; Grallert, Harald; Illig, Thomas; Ismail, Khadeeja; Ollikainen, Miina; Silén, Yasmina; Keski-Rahkonen, Anna; Bulik, Cynthia M; Collier, David A; Zeggini, Eleftheria; Hebebrand, Johannes; Scherag, André; Hinney, Anke

2018-04-01

Patients with anorexia nervosa (AN) are ideally suited to identify differentially methylated genes in response to starvation. We examined high-throughput DNA methylation derived from whole blood of 47 females with AN, 47 lean females without AN and 100 population-based females to compare AN with both controls. To account for different cell type compositions, we applied two reference-free methods (FastLMM-EWASher, RefFreeEWAS) and searched for consensus CpG sites identified by both methods. We used a validation sample of five monozygotic AN-discordant twin pairs. Fifty-one consensus sites were identified in AN vs. lean and 81 in AN vs. population-based comparisons. These sites have not been reported in AN methylation analyses, but for the latter comparison 54/81 sites showed directionally consistent differential methylation effects in the AN-discordant twins. For a single nucleotide polymorphism rs923768 in CSGALNACT1 a nearby site was nominally associated with AN. At the gene level, we confirmed hypermethylated sites at TNXB. We found support for a locus at NR1H3 in the AN vs. lean control comparison, but the methylation direction was opposite to the one previously reported. We confirm genes like TNXB previously described to comprise differentially methylated sites, and highlight further sites that might be specifically involved in AN starvation processes.

Epigenome-Wide Association Study of Tic Disorders.

Science.gov (United States)

Zilhão, Nuno R; Padmanabhuni, Shanmukha S; Pagliaroli, Luca; Barta, Csaba; Smit, Dirk J A; Cath, Danielle; Nivard, Michel G; Baselmans, Bart M L; van Dongen, Jenny; Paschou, Peristera; Boomsma, Dorret I

2015-12-01

Tic disorders are moderately heritable common psychiatric disorders that can be highly troubling, both in childhood and in adulthood. In this study, we report results obtained in the first epigenome-wide association study (EWAS) of tic disorders. The subjects are participants in surveys at the Netherlands Twin Register (NTR) and the NTR biobank project. Tic disorders were measured with a self-report version of the Yale Global Tic Severity Scale Abbreviated version (YGTSS-ABBR), included in the 8th wave NTR data collection (2008). DNA methylation data consisted of 411,169 autosomal methylation sites assessed by the Illumina Infinium HumanMethylation450 BeadChip Kit (HM450k array). Phenotype and DNA methylation data were available in 1,678 subjects (mean age = 41.5). No probes reached genome-wide significance (p tic disorders. The top significantly enriched gene ontology (GO) terms among higher ranking methylation sites included anatomical structure morphogenesis (GO:0009653, p = 4.6 × 10-(15)) developmental process (GO:0032502, p = 2.96 × 10(-12)), and cellular developmental process (GO:0048869, p = 1.96 × 10(-12)). Overall, these results provide a first insight into the epigenetic mechanisms of tic disorders. This first study assesses the role of DNA methylation in tic disorders, and it lays the foundations for future work aiming to unravel the biological mechanisms underlying the architecture of this disorder.

Personalized skincare: from molecular basis to clinical and commercial applications

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Markiewicz E

2018-04-01

Full Text Available Ewa Markiewicz, Olusola Clement Idowu Research & Development, Hexis Lab, Science Central, The Core, Bath Lane, Newcastle upon Tyne, UK Abstract: Individual responses of human skin to the environmental stress are determined by differences in the anatomy and physiology that are closely linked to the genetic characteristics such as pigmentation. Ethnic skin phenotypes can be distinguished based on defined genotypic traits, structural organization and compartmentalized sensitivity to distinct extrinsic aging factors. These differences are not only responsible for the variation in skin performance after exposure to damaging conditions, but can also affect the mechanisms of drug absorption, sensitization and other longer term effects. The unique characteristics of the individual skin function and, particularly, of the ethnic skin type are currently considered to shape the future of clinical and pharmacologic interventions as a basis for personalized skincare. Individual approaches to skincare render a novel and actively growing area with a range of biomedical and commercial applications within cosmetics industry. In this review, we summarize the aspects of the molecular and clinical manifestations of the environmental stress on human skin and proposed protective mechanisms that are linked to ethnic differences and pathophysiology of extrinsic skin aging. We subsequently discuss the possible applications and translation of this knowledge into personalized skincare. Keywords: pigmentation, gene polymorphism, photodamage, environmental stress, cosmetics

Materials from seminar session of the 3.general assembly of Polish Nuclear Society; 3.Walny Zjazd Polskiego Towarzystwa Nukleonicznego. Materialy sesji seminaryjnej

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-12-31

This publication edited as a scientific report of the Institute of Atomic Energy contains papers presented on the seminar session accompanying the 3rd General Assembly of Polish Nuclear Society. Five of these are dealing with the present situation in Poland in the framework of the following subjects: foreseeing electricity demand as a significant factor of development of electricity generation sector and nuclear option choice; present state and development trends of nuclear technique applications in industry, agriculture, health and environment protection; radioactive waste management especially related to the storage of spent fuel from EWA and MARIA research reactors; present educational problems in nuclear science and technology. The problems of nuclear power could not be excluded from the session, although it does not exist in Poland and no plans foresee it currently. The paper on nuclear power contains an extensive summary of nuclear power development worldwide, its safety problems, economic competitiveness and public acceptance. The so called ``Sellafield phenomenon`` considering the growth of leukaemia deaths of children living near that reprocessing plant in England has been commented in mass media criticizing nuclear energy application. The paper on this problem present the results of investigations and hypotheses on reasons having caused this phenomenon. The declaration of the International Council of Nuclear Societies on the role of nuclear science and technology in supporting the development is also included in the report.

Ars bene moriendi of Piotr Tylicki bishop of Cracow in the Letter of Fryderyk Szembek to Wawrzyniec Gembicki

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Bartłomiej Michał Wołyniec

2014-12-01

Full Text Available In the year 1617 in Cracow printer Andrzej Piotrowczyk published book under the title O śmierci świętej pamięci Jego Mości X. Piotra Tylickiego krakowskiego biskupa […] i nabożnym ku niej przygotowaniu jego List do […] X. Wawrzyńca Gembickiego z Bożej Łaski arcybiskupa gnieźnieńskiego […]. Author of this work was one of the Cracow’s Jesuits Fryderyk Szembek (1575–1644. He wrote his letter to informed about death of bishop Piotr Tylicki to archbishop of Gniezno Wawrzyniec Gembicki (1559–1624, who was friend of dead. This work was however published in the short time, as it was mentioned, because of decision of executors of the bishop’s Piotr Tylicki will, religious superiors to Fryderyk Szembek and new bishop of Cracow, Marcin Szyszkowski (1554–1630. Szembek’s letter is example of ars bene moriendi writings. This type of literature have different forms, but all of them prepare men to the death. Therefore, they contain examples of attitudes and thoughts for dying person. Bishop Piotr Tylicki was presented in this letter as a exemplary senator, descendant of the nobles and patriot who loved his motherland, Poland. Bishop however had practiced his virtues. Those included religiosity, humility and care of piety of others. On the other hand we have to remember that, he was also the tutor of author. What is more, archbishop of Gniezno, as it was mentioned, was “old and kind” friend of bishop Piotr Tylicki.

Direct assays of radiation-induced DNA base lesions in mammalian cells: Technical progress report, July 1, 1986--December 1, 1988

International Nuclear Information System (INIS)

Wheeler, K.T. Jr.

1988-01-01

Our cesium irradiator was installed in April 1987 and has the capability of irradiating DNA solutions, cells and animals at dose rates from >60 Gy/min to <10/sup /minus/2/ Gy/min. By early summer all of the dosimetry and set-ups were established to perform this research. In may 1987, Dr. Krystyna Lesiak left to return to the National Institutes of Health. However, she has remained a collaborator over the past 1/1/2/ years. She has synthesized a large lot of α-deoxyadenosine, isolated a large batch of both the R and S isomer of cyclodeoxyadenosine and has capped the α-deoxyadenonsine for use in a DNA synthesizer that uses phosphoramidite chemistry. In November 1987, Dr. Andrzej Surowiec joined our unit as a Visiting Research Assistant Professor. Dr. Surowiec has a MS degree in electrical engineering and did his Ph.D. in Biophysics studying the conductivity of DNA in dilute solution. He has been performing the helix-coil transition experiments. In November 1987, Dr. Steven Swarts also joined our unit as a Postdoctoral Fellow. He received his Ph.D. from Oakland University under Dr. Michael Sevilla with whom we have a collaboration studying the induction of base damage in hydrated DNA. Dr. Swarts has a strong background in spectroscopy and, therefore, was a key individual for determination of the limitations of the HPLC assays and the establishment of a GC/MS capability equivalent to Dr. M. Dizdaroglu at the National Bureau of Standards. 9 refs., 1 tab

Can stormwater be detected by algae in an urban reef in Hawai‘i?

International Nuclear Information System (INIS)

Erin Cox, T.; Smith, Celia M.; Popp, Brian N.; Foster, Michael S.; Abbott, Isabella A.

2013-01-01

Highlights: • Invasive and native algae are a part of a reef assemblage located in an urban area. • Algal nitrogen (N) composition tested if N was enriched from storm-drain outlets. • Elevated N values indicated a mixed, high nutrient environment. • Storm-drains as plausible nitrogenous source was not supported. • Temporal and spatial values indicate algae incorporated terrestrial derived N. -- Abstract: Nitrogen (N) enrichment of tropical reefs can result in the dominance of invasive algae. The invasive alga Acanthophora spicifera and the native alga Laurencia nidifica are part of a diverse reef assemblage in ‘Ewa Beach, O‘ahu. Their N contents and δ 15 N values were investigated to determine if N was enriched and to evaluate potential nitrogenous sources near and removed from storm-drain outlets. δ 15 N values of algae (3.8–17.7‰) were within and above the range for algae around the island (1.9–11.9‰). Elevated algae N isotope values (δ 15 N > +7‰, [N] > 1.6%) and seawater nitrate + nitrite levels (0.59–7.93 μM) indicated a mixed, high nutrient environment. The overlap in δ 15 N values with multiple nitrogenous sources precluded identification. However, spatial and temporal patterns did not support stormwater as the dominant, nitrogenous source. Patterns were congruent with algal incorporation of terrestrial derived N, subjected to a high degree of biogeochemical cycling

Toward a panoramic perspective of the association between environmental factors and cardiovascular disease: An environment-wide association study from National Health and Nutrition Examination Survey 1999-2014.

Science.gov (United States)

Zhuang, Xiaodong; Guo, Yue; Ni, Ao; Yang, Daya; Liao, Lizhen; Zhang, Shaozhao; Zhou, Huimin; Sun, Xiuting; Wang, Lichun; Wang, Xueqin; Liao, Xinxue

2018-06-04

An environment-wide association study (EWAS) may be useful to comprehensively test and validate associations between environmental factors and cardiovascular disease (CVD) in an unbiased manner. Data from National Health and Nutrition Examination Survey (1999-2014) were randomly 50:50 spilt into training set and testing set. CVD was ascertained by a self-reported diagnosis of myocardial infarction, coronary heart disease or stroke. We performed multiple linear regression analyses associating 203 environmental factors and 132 clinical phenotypes with CVD in training set (false discovery rate multicollinearity elimination and variable importance ranking. Discriminative power of factors for CVD was calculated by area under the receiver operating characteristic (AUROC). Overall, 43,568 participants with 4084 (9.4%) CVD were included. After adjusting for age, sex, race, body mass index, blood pressure and socio-economic level, we identified 5 environmental variables and 19 clinical phenotypes associated with CVD in training and testing dataset. Top five factors in RF importance ranking were: waist, glucose, uric acid, and red cell distribution width and glycated hemoglobin. AUROC of the RF model was 0.816 (top 5 factors) and 0.819 (full model). Sensitivity analyses reveal no specific moderators of the associations. Our systematic evaluation provides new knowledge on the complex array of environmental correlates of CVD. These identified correlates may serve as a complementary approach to CVD risk assessment. Our findings need to be probed in further observational and interventional studies. Copyright © 2018. Published by Elsevier Ltd.

Comparison of the effectiveness of complex decongestive therapy and compression bandaging as a method of treatment of lymphedema in the elderly

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Zasadzka E

2018-05-01

Full Text Available Ewa Zasadzka,1 Tomasz Trzmiel,1 Maria Kleczewska,2 Mariola Pawlaczyk1 1Department of Geriatric Medicine and Gerontology, Karol Marcinkowski University of Medical Sciences, Poznan, Poland; 2Day Rehabilitation Center, Hospicjum Palium, Poznań, Poland Background: Lymphedema is a chronic condition which significantly lowers the quality of patient life, particularly among elderly populations, whose mobility and physical function are often reduced. Objectives: The aim of the study was to compare the effectiveness of multi-layer compression bandaging (MCB and complex decongestive therapy (CDT, and to show that MCB is a cheaper, more accessible and less labor intensive method of treating lymphedema in elderly patients. Patients and methods: The study included 103 patients (85 women and 18 men aged ≥60 years, with unilateral lower limb lymphedema. The subjects were divided into two groups: 50 treated with CDT and 53 with MCB. Pre- and post-treatment BMI, and average and maximum circumference of the edematous extremities were analyzed. Results: Reduction in swelling in both groups was achieved after 15 interventions. Both therapies demonstrated similar efficacy in reducing limb volume and circumference, but MCB showed greater efficacy in reducing the maximum circumference. Conclusion: Compression bandaging is a vital component of CDT. Maximum lymphedema reduction during therapy and maintaining its effect cannot be achieved without it. It also demonstrates its effectiveness as an independent method, which can reduce therapy cost and accessibility. Keywords: lymphedema, elderly, therapy, compression bandaging

Tobacco smoking leads to extensive genome-wide changes in DNA methylation.

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Sonja Zeilinger

Full Text Available Environmental factors such as tobacco smoking may have long-lasting effects on DNA methylation patterns, which might lead to changes in gene expression and in a broader context to the development or progression of various diseases. We conducted an epigenome-wide association study (EWAs comparing current, former and never smokers from 1793 participants of the population-based KORA F4 panel, with replication in 479 participants from the KORA F3 panel, carried out by the 450K BeadChip with genomic DNA obtained from whole blood. We observed wide-spread differences in the degree of site-specific methylation (with p-values ranging from 9.31E-08 to 2.54E-182 as a function of tobacco smoking in each of the 22 autosomes, with the percent of variance explained by smoking ranging from 1.31 to 41.02. Depending on cessation time and pack-years, methylation levels in former smokers were found to be close to the ones seen in never smokers. In addition, methylation-specific protein binding patterns were observed for cg05575921 within AHRR, which had the highest level of detectable changes in DNA methylation associated with tobacco smoking (-24.40% methylation; p = 2.54E-182, suggesting a regulatory role for gene expression. The results of our study confirm the broad effect of tobacco smoking on the human organism, but also show that quitting tobacco smoking presumably allows regaining the DNA methylation state of never smokers.

Tobacco smoking leads to extensive genome-wide changes in DNA methylation.

Science.gov (United States)

Zeilinger, Sonja; Kühnel, Brigitte; Klopp, Norman; Baurecht, Hansjörg; Kleinschmidt, Anja; Gieger, Christian; Weidinger, Stephan; Lattka, Eva; Adamski, Jerzy; Peters, Annette; Strauch, Konstantin; Waldenberger, Melanie; Illig, Thomas

2013-01-01

Environmental factors such as tobacco smoking may have long-lasting effects on DNA methylation patterns, which might lead to changes in gene expression and in a broader context to the development or progression of various diseases. We conducted an epigenome-wide association study (EWAs) comparing current, former and never smokers from 1793 participants of the population-based KORA F4 panel, with replication in 479 participants from the KORA F3 panel, carried out by the 450K BeadChip with genomic DNA obtained from whole blood. We observed wide-spread differences in the degree of site-specific methylation (with p-values ranging from 9.31E-08 to 2.54E-182) as a function of tobacco smoking in each of the 22 autosomes, with the percent of variance explained by smoking ranging from 1.31 to 41.02. Depending on cessation time and pack-years, methylation levels in former smokers were found to be close to the ones seen in never smokers. In addition, methylation-specific protein binding patterns were observed for cg05575921 within AHRR, which had the highest level of detectable changes in DNA methylation associated with tobacco smoking (-24.40% methylation; p = 2.54E-182), suggesting a regulatory role for gene expression. The results of our study confirm the broad effect of tobacco smoking on the human organism, but also show that quitting tobacco smoking presumably allows regaining the DNA methylation state of never smokers.

A method to associate all possible combinations of genetic and environmental factors using GxE landscape plot.

Science.gov (United States)

Nagaie, Satoshi; Ogishima, Soichi; Nakaya, Jun; Tanaka, Hiroshi

2015-01-01

Genome-wide association studies (GWAS) and linkage analysis has identified many single nucleotide polymorphisms (SNPs) related to disease. There are many unknown SNPs whose minor allele frequencies (MAFs) as low as 0.005 having intermediate effects with odds ratio between 1.5~3.0. Low frequency variants having intermediate effects on disease pathogenesis are believed to have complex interactions with environmental factors called gene-environment interactions (GxE). Hence, we describe a model using 3D Manhattan plot called GxE landscape plot to visualize the association of p-values for gene-environment interactions (GxE). We used the Gene-Environment iNteraction Simulator 2 (GENS2) program to simulate interactions between two genetic loci and one environmental factor in this exercise. The dataset used for training contains disease status, gender, 20 environmental exposures and 100 genotypes for 170 subjects, and p-values were calculated by Cochran-Mantel-Haenszel chi-squared test on known data. Subsequently, we created a 3D GxE landscape plot of negative logarithm of the association of p-values for all the possible combinations of genetic and environmental factors with their hierarchical clustering. Thus, the GxE landscape plot is a valuable model to predict association of p-values for GxE and similarity among genotypes and environments in the context of disease pathogenesis. GxE - Gene-environment interactions, GWAS - Genome-wide association study, MAFs - Minor allele frequencies, SNPs - Single nucleotide polymorphisms, EWAS - Environment-wide association study, FDR - False discovery rate, JPT+CHB - HapMap population of Japanese in Tokyo, Japan - Han Chinese in Beijing.

Chemical exchange rotation transfer imaging of intermediate-exchanging amines at 2 ppm.

Science.gov (United States)

Zu, Zhongliang; Louie, Elizabeth A; Lin, Eugene C; Jiang, Xiaoyu; Does, Mark D; Gore, John C; Gochberg, Daniel F

2017-10-01

Chemical exchange saturation transfer (CEST) imaging of amine protons exchanging at intermediate rates and whose chemical shift is around 2 ppm may provide a means of mapping creatine. However, the quantification of this effect may be compromised by the influence of overlapping CEST signals from fast-exchanging amines and hydroxyls. We aimed to investigate the exchange rate filtering effect of a variation of CEST, named chemical exchange rotation transfer (CERT), as a means of isolating creatine contributions at around 2 ppm from other overlapping signals. Simulations were performed to study the filtering effects of CERT for the selection of transfer effects from protons of specific exchange rates. Control samples containing the main metabolites in brain, bovine serum albumin (BSA) and egg white albumen (EWA) at their physiological concentrations and pH were used to study the ability of CERT to isolate molecules with amines at 2 ppm that exchange at intermediate rates, and corresponding methods were used for in vivo rat brain imaging. Simulations showed that exchange rate filtering can be combined with conventional filtering based on chemical shift. Studies on samples showed that signal contributions from creatine can be separated from those of other metabolites using this combined filter, but contributions from protein amines may still be significant. This exchange filtering can also be used for in vivo imaging. CERT provides more specific quantification of amines at 2 ppm that exchange at intermediate rates compared with conventional CEST imaging. Copyright © 2017 John Wiley & Sons, Ltd.

Education in wrist arthroscopy: past, present and future.

Science.gov (United States)

Obdeijn, M C; Bavinck, N; Mathoulin, C; van der Horst, C M A M; Schijven, M P; Tuijthof, G J M

2015-05-01

Arthroscopy has assumed an important place in wrist surgery. It requires specific operative skills that are now mainly acquired in the operating room. In other fields of endoscopic surgery, e-learning and virtual reality (VR) have introduced new perspectives in teaching skills. This leads to the following research question: Could the current way of teaching wrist arthroscopy skills be supported using new educational media, such as e-learning and simulator training? The literature was searched for available methods of teaching endoscopic skills. Articles were assessed on the evidence of validity. In addition, a survey was sent to all members of the European Wrist Arthroscopy Society (EWAS) to find out whether hand surgeons express a need to embrace modern educational tools such as e-learning or simulators for training of wrist arthroscopy skills. This study shows that the current way of teaching wrist arthroscopy skills can be supported using new educational media, such as e-learning and simulator training. Literature indicates that e-learning can be a valuable tool for teaching basic knowledge of arthroscopy and supports the hypothesis that the use of virtual reality and simulators in training enhances operative skills in surgical trainees. This survey indicates that 55 out of 65 respondents feel that an e-learning program would be a valuable asset and 62 out of the 65 respondents are positive on the additional value of wrist arthroscopy simulator in training. Study results support the need and relevance to strengthen current training of wrist arthroscopy using e-learning and simulator training. V.

Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy.

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Ulrike Esslinger

Full Text Available Dilated cardiomyopathy (DCM is an important cause of heart failure with a strong familial component. We performed an exome-wide array-based association study (EWAS to assess the contribution of missense variants to sporadic DCM.116,855 single nucleotide variants (SNVs were analyzed in 2796 DCM patients and 6877 control subjects from 6 populations of European ancestry. We confirmed two previously identified associations with SNVs in BAG3 and ZBTB17 and discovered six novel DCM-associated loci (Q-value<0.01. The lead-SNVs at novel loci are common and located in TTN, SLC39A8, MLIP, FLNC, ALPK3 and FHOD3. In silico fine mapping identified HSPB7 as the most likely candidate at the ZBTB17 locus. Rare variant analysis (MAF<0.01 demonstrated significant association for TTN variants only (P = 0.0085. All candidate genes but one (SLC39A8 exhibit preferential expression in striated muscle tissues and mutations in TTN, BAG3, FLNC and FHOD3 are known to cause familial cardiomyopathy. We also investigated a panel of 48 known cardiomyopathy genes. Collectively, rare (n = 228, P = 0.0033 or common (n = 36, P = 0.019 variants with elevated in silico severity scores were associated with DCM, indicating that the spectrum of genes contributing to sporadic DCM extends beyond those identified here.We identified eight loci independently associated with sporadic DCM. The functions of the best candidate genes at these loci suggest that proteostasis regulation might play a role in DCM pathophysiology.

2K09 and thereafter : the coming era of integrative bioinformatics, systems biology and intelligent computing for functional genomics and personalized medicine research

Science.gov (United States)

2010-01-01

Significant interest exists in establishing synergistic research in bioinformatics, systems biology and intelligent computing. Supported by the United States National Science Foundation (NSF), International Society of Intelligent Biological Medicine (http://www.ISIBM.org), International Journal of Computational Biology and Drug Design (IJCBDD) and International Journal of Functional Informatics and Personalized Medicine, the ISIBM International Joint Conferences on Bioinformatics, Systems Biology and Intelligent Computing (ISIBM IJCBS 2009) attracted more than 300 papers and 400 researchers and medical doctors world-wide. It was the only inter/multidisciplinary conference aimed to promote synergistic research and education in bioinformatics, systems biology and intelligent computing. The conference committee was very grateful for the valuable advice and suggestions from honorary chairs, steering committee members and scientific leaders including Dr. Michael S. Waterman (USC, Member of United States National Academy of Sciences), Dr. Chih-Ming Ho (UCLA, Member of United States National Academy of Engineering and Academician of Academia Sinica), Dr. Wing H. Wong (Stanford, Member of United States National Academy of Sciences), Dr. Ruzena Bajcsy (UC Berkeley, Member of United States National Academy of Engineering and Member of United States Institute of Medicine of the National Academies), Dr. Mary Qu Yang (United States National Institutes of Health and Oak Ridge, DOE), Dr. Andrzej Niemierko (Harvard), Dr. A. Keith Dunker (Indiana), Dr. Brian D. Athey (Michigan), Dr. Weida Tong (FDA, United States Department of Health and Human Services), Dr. Cathy H. Wu (Georgetown), Dr. Dong Xu (Missouri), Drs. Arif Ghafoor and Okan K Ersoy (Purdue), Dr. Mark Borodovsky (Georgia Tech, President of ISIBM), Dr. Hamid R. Arabnia (UGA, Vice-President of ISIBM), and other scientific leaders. The committee presented the 2009 ISIBM Outstanding Achievement Awards to Dr. Joydeep Ghosh (UT

Archaeological and Paleontological Investigation at Kalaeloa (Barber’s Point), Honouliuli, ’EWA, O’Ahu Island, Federal Study Areas 1a and 1b, and State of Hawaii Optional Area 1,

Science.gov (United States)

1981-07-01

gravel, slightly sticky, slightly plastic, massive structure. Granule size limestone decreases with depth. Color whitens with depth influenced by neutral...fish. Vertebrae from shark or ray are present in 2787 and 2745 and fragments of large toothed jaws, tentatively identified as crevally (ulua) are present...a white enameled 5-gallon liquid dispenser sits on top a wooden crate. The barracks is wired for lighting with a drop-cord light over the desks

Ewa Głażewska, Urszula Kusio, Komunikacja niewerbalna. Płeć i kultura. Wybrane zagadnienia, Lublin, Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej, 2012, 255 s., ISBN 978-83-7784-177-8

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Paulina Banaśkiewicz

2014-07-01

Full Text Available Autorka recenzji opisuje pokrótce zawartość dwóch części książki na temat komunikacji niewerbalnej celem skupienia się na trzech walorach publikacji: konstrukcji książki, prezentacji niezbyt dobrze znanych w Polsce koncepcji wybitnych antropologów i socjologów oraz liczebności eksplikacji, które służą zilustrowaniu rozważań teoretycznych.English abstractThe author briefly describes the contents of the two parts of the book about non-verbal communication to focus on three qualities: design of the book, not very well known in Poland concepts of eminent anthropologists and sociologists and the number of explications, which illustrate the theoretical considerations. 

Toxicity studies of six types of carbon nanoparticles in a chicken-embryo model

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Kurantowicz N

2017-04-01

Full Text Available Natalia Kurantowicz,1 Ewa Sawosz,1 Gabriela Halik,1 Barbara Strojny,1 Anna Hotowy,1 Marta Grodzik,1 Radosław Piast,2 Wanvimol Pasanphan,3 André Chwalibog4 1Department of Animal Nutrition and Biotechnology, Warsaw University of Life Sciences, 2Faculty of Chemistry, Warsaw University, Warsaw, Poland; 3Department of Materials Science, Faculty of Science, Kasetsart University, Bangkok, Thailand; 4Department of Veterinary Clinical and Animal Sciences, University of Copenhagen, Copenhagen, Denmark Abstract: In the present study, the toxicity of six different types of carbon nanoparticles (CNPs was investigated using a chicken-embryo model. Fertilized chicken eggs were divided into the following treatment groups: placebo, diamond NPs, graphite NPs, pristine graphene, small graphene oxide, large graphene oxide, and reduced graphene oxide. Experimental solutions at a concentration of 500 µg/mL were administrated into the egg albumin. Gross pathology and the rate of survival were examined after 5, 10, 15, and 20 days of incubation. After 20 days of incubation, blood samples were collected and the weight of the body and organs measured. The relative ratio of embryo survival decreased after treatment all treatments except diamond NPs. There was no correlation between the rate of survival and the ζ-potential or the surface charge of the CNPs in solution. Body and organ weight, red blood-cell morphology, blood serum biochemical parameters, and oxidative damage in the liver did not differ among the groups. These results indicate that CNPs can remain in blood circulation without any major side effects, suggesting their potential applicability as vehicles for drug delivery or active compounds per se. However, there is a need for further investigation of their properties, which vary depending on production methods and surface functionalization. Keywords: nanoparticles, diamond, graphite, graphene, toxicity, red blood cells, oxidative stress, surface charge

Apresentação do Dossiê

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Maria Cecília Coelho

2013-12-01

Full Text Available Este dossiê reúne textos apresentados, em sua maioria, durante o XIX Congresso da Sociedade Brasileira de Estudos Clássicos e no decorrer do I Simpósio Luso-Brasileiro de Estudos Clássicos – O Futuro do Passado, que aconteceu em julho de 2013, em Brasília/Distrito Federal. O dossiê contém quatro artigos e um ensaio, lido em uma palestra, ao qual segue anexo um comentário de seu moderador. Três dos artigos são frutos do painel proposto e organizado, durante o XIX Congresso, pelo Núcleo de Estudos Antigos e Medievais da Faculdade de Letras da Universidade Federal de Minas Gerais (NEAM/FALE/UFMG, do qual sou membro. No painel, intitulado “Recepção da cultura greco-romana no cinema, no teatro e na literatura”, foram apresentados textos de autoria de professores da área de língua e literatura gregas, que trabalham na Argentina, nos Estados Unidos e na Polônia: Claudia Fernández (Universidade de La Plata, Eric Dugdale (Gustavus Adolphus College e Ewa Skwara (Adam-Mickiewicz University, respectivamente. Quanto ao ensaio, trata-se do texto do cineasta português João Canijo, em cuja obra se destaca a adaptação de tragédias gregas para o cinema. O ensaio é seguido do comentário de Christian Werner (Universidade de São Paulo, tradutor e professor de língua e literatura gregas. O quarto artigo, de minha autoria, apesar de ter sido resultado, em parte, de uma palestra que apresentei em outro momento (no VI Colóquio Filosofia e Ficção – Phantasia e Phantasmas, foi, pela proximidade com o tema do painel que coordenei nesse XIX Congresso, inserido neste dossiê.

Genome-wide DNA methylation study in human placenta identifies novel loci associated with maternal smoking during pregnancy.

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Morales, Eva; Vilahur, Nadia; Salas, Lucas A; Motta, Valeria; Fernandez, Mariana F; Murcia, Mario; Llop, Sabrina; Tardon, Adonina; Fernandez-Tardon, Guillermo; Santa-Marina, Loreto; Gallastegui, Mara; Bollati, Valentina; Estivill, Xavier; Olea, Nicolas; Sunyer, Jordi; Bustamante, Mariona

2016-10-01

We conducted an epigenome-wide association study (EWAS) of DNA methylation in placenta in relation to maternal tobacco smoking during pregnancy and examined whether smoking-induced changes lead to low birthweight. DNA methylation in placenta was measured using the Illumina HumanMethylation450 BeadChip in 179 participants from the INfancia y Medio Ambiente (INMA) birth cohort. Methylation levels across 431 311 CpGs were tested for differential methylation between smokers and non-smokers in pregnancy. We took forward three top-ranking loci for further validation and replication by bisulfite pyrosequencing using data of 248 additional participants of the INMA cohort. We examined the association of methylation at smoking-associated loci with birthweight by applying a mediation analysis and a two-sample Mendelian randomization approach. Fifty CpGs were differentially methylated in placenta between smokers and non-smokers during pregnancy [false discovery rate (FDR) < 0.05]. We validated and replicated differential methylation at three top-ranking loci: cg27402634 located between LINC00086 and LEKR1, a gene previously related to birthweight in genome-wide association studies; cg20340720 (WBP1L); and cg25585967 and cg12294026 (TRIO). Dose-response relationships with maternal urine cotinine concentration during pregnancy were confirmed. Differential methylation at cg27402634 explained up to 36% of the lower birthweight in the offspring of smokers (Sobel P-value < 0.05). A two-sample Mendelian randomization analysis provided evidence that decreases in methylation levels at cg27402634 lead to decreases in birthweight. We identified novel loci differentially methylated in placenta in relation to maternal smoking during pregnancy. Adverse effects of maternal smoking on birthweight of the offspring may be mediated by alterations in the placental methylome. © The Author 2016; all rights reserved. Published by Oxford University Press on behalf of the International

A participação dos ergonomistas nos projetos organizacionais

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Marçal Jackson

1999-12-01

Full Text Available Neste texto, pretende-se apresentar, em resposta às condicionantes conceituais e metodológicas colocadas por Salerno, uma abordagem metodológica, a abordagem da atividade futura (AAF, que viabiliza a participação dos ergonomistas em projetos organizacionais. Nessa abordagem, que tem a Análise Ergonômica do Trabalho (AET como base, os ergonomistas não sustentam unicamente a posição clínica, característica da AET, mas assumem o papel de "atores do processo de projeto" a fim de cooperar com os diferentes atores da empresa: diretores, gerentes, engenheiros, trabalhadores. Todavia, a participação efetiva da Ergonomia depende de nova forma de conceber a organização, que deve ser abordada não somente através de sua dimensão estrutural, mas também através das "regulações sociais necessárias à manutenção e à construção da organização do trabalho".In response to Salerno's theoretical and methodological constraints to ergonomists participation in organisational design process, this paper proposes a new approach based in future work activity forecasting. Even if the Ergonomie Work Analysis (EWA is the underlying methodological tool, in this approach, ergonomists must assume a new role, as "actors of the design process", and co-operate with the others company actors: managers, engineers, foremen and workers. But to be more effective, ergonomie intervention needs a new framework of "organisation" issues. To be more effective, it will be argued that one must approach organisâtionnal design not only by its structural components but also by its inherent social interactions and adjustments.

Visualization of gold and platinum nanoparticles interacting with Salmonella Enteritidis and Listeria monocytogenes

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Ewa Sawosz

2010-08-01

Full Text Available Ewa Sawosz1, André Chwalibog2, Jacek Szeliga3, Filip Sawosz2, Marta Grodzik1, Marlena Rupiewicz1, Tomasz Niemiec1, Katarzyna Kacprzyk11Division of Biotechnology and Biochemistry of Nutrition, Warsaw University of Life Sciences, Warsaw, Poland; 2Department of Basic Animal and Veterinary Sciences, University of Copenhagen, Copenhagen, Denmark; 3Division of Microbiology of Analytical Centre, Warsaw University of Life Sciences, Warsaw, PolandPurpose: Rapid development of nanotechnology has recently brought significant attention to the extraordinary biological features of nanomaterials. The objective of the present ­investigation was to evaluate morphological characteristics of the assembles of gold and platinum nanoparticles (nano-Au and nano-Pt respectively, with Salmonella Enteritidis (Gram-negative and Listeria monocytogenes (Gram-positive, to reveal possibilities of constructing bacteria-nanoparticle vehicles.Methods: Hydrocolloids of nano-Au or nano-Pt were added to two bacteria suspensions in the following order: nano-Au + Salmonella Enteritidis; nano-Au + Listeria monocytogenes; nano-Pt + Salmonella Enteritidis; nano-Pt + Listeria monocytogenes. Samples were inspected by transmission electron microscope.Results: Visualization of morphological interaction between nano-Au and Salmonella Enteritidis and Listeria monocytogenes, showed that nano-Au were aggregated within flagella or biofilm network and did not penetrate the bacterial cell. The analysis of morphological effects of interaction of nano-Pt with bacteria revealed that nano-Pt entered cells of Listeria monocytogenes and were removed from the cells. In the case of Salmonella Enteritidis, nano-Pt were seen inside bacteria cells, probably bound to DNA and partly left bacterial cells. After washing and centrifugation, some of the nano-Pt-DNA complexes were observed within Salmonella Enteritidis.Conclusion: The results indicate that the bacteria could be used as a vehicle to deliver nano

Adjustment of Cell-Type Composition Minimizes Systematic Bias in Blood DNA Methylation Profiles Derived by DNA Collection Protocols.

Science.gov (United States)

Shiwa, Yuh; Hachiya, Tsuyoshi; Furukawa, Ryohei; Ohmomo, Hideki; Ono, Kanako; Kudo, Hisaaki; Hata, Jun; Hozawa, Atsushi; Iwasaki, Motoki; Matsuda, Koichi; Minegishi, Naoko; Satoh, Mamoru; Tanno, Kozo; Yamaji, Taiki; Wakai, Kenji; Hitomi, Jiro; Kiyohara, Yutaka; Kubo, Michiaki; Tanaka, Hideo; Tsugane, Shoichiro; Yamamoto, Masayuki; Sobue, Kenji; Shimizu, Atsushi

2016-01-01

Differences in DNA collection protocols may be a potential confounder in epigenome-wide association studies (EWAS) using a large number of blood specimens from multiple biobanks and/or cohorts. Here we show that pre-analytical procedures involved in DNA collection can induce systematic bias in the DNA methylation profiles of blood cells that can be adjusted by cell-type composition variables. In Experiment 1, whole blood from 16 volunteers was collected to examine the effect of a 24 h storage period at 4°C on DNA methylation profiles as measured using the Infinium HumanMethylation450 BeadChip array. Our statistical analysis showed that the P-value distribution of more than 450,000 CpG sites was similar to the theoretical distribution (in quantile-quantile plot, λ = 1.03) when comparing two control replicates, which was remarkably deviated from the theoretical distribution (λ = 1.50) when comparing control and storage conditions. We then considered cell-type composition as a possible cause of the observed bias in DNA methylation profiles and found that the bias associated with the cold storage condition was largely decreased (λ adjusted = 1.14) by taking into account a cell-type composition variable. As such, we compared four respective sample collection protocols used in large-scale Japanese biobanks or cohorts as well as two control replicates. Systematic biases in DNA methylation profiles were observed between control and three of four protocols without adjustment of cell-type composition (λ = 1.12-1.45) and no remarkable biases were seen after adjusting for cell-type composition in all four protocols (λ adjusted = 1.00-1.17). These results revealed important implications for comparing DNA methylation profiles between blood specimens from different sources and may lead to discovery of disease-associated DNA methylation markers and the development of DNA methylation profile-based predictive risk models.

U.S. Tsunami Information technology (TIM) Modernization:Developing a Maintainable and Extensible Open Source Earthquake and Tsunami Warning System

Science.gov (United States)

Hellman, S. B.; Lisowski, S.; Baker, B.; Hagerty, M.; Lomax, A.; Leifer, J. M.; Thies, D. A.; Schnackenberg, A.; Barrows, J.

2015-12-01

Tsunami Information technology Modernization (TIM) is a National Oceanic and Atmospheric Administration (NOAA) project to update and standardize the earthquake and tsunami monitoring systems currently employed at the U.S. Tsunami Warning Centers in Ewa Beach, Hawaii (PTWC) and Palmer, Alaska (NTWC). While this project was funded by NOAA to solve a specific problem, the requirements that the delivered system be both open source and easily maintainable have resulted in the creation of a variety of open source (OS) software packages. The open source software is now complete and this is a presentation of the OS Software that has been funded by NOAA for benefit of the entire seismic community. The design architecture comprises three distinct components: (1) The user interface, (2) The real-time data acquisition and processing system and (3) The scientific algorithm library. The system follows a modular design with loose coupling between components. We now identify the major project constituents. The user interface, CAVE, is written in Java and is compatible with the existing National Weather Service (NWS) open source graphical system AWIPS. The selected real-time seismic acquisition and processing system is open source SeisComp3 (sc3). The seismic library (libseismic) contains numerous custom written and wrapped open source seismic algorithms (e.g., ML/mb/Ms/Mwp, mantle magnitude (Mm), w-phase moment tensor, bodywave moment tensor, finite-fault inversion, array processing). The seismic library is organized in a way (function naming and usage) that will be familiar to users of Matlab. The seismic library extends sc3 so that it can be called by the real-time system, but it can also be driven and tested outside of sc3, for example, by ObsPy or Earthworm. To unify the three principal components we have developed a flexible and lightweight communication layer called SeismoEdex.

Nanoparticles containing allotropes of carbon have genotoxic effects on glioblastomamultiforme cells

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Hinzmann M

2014-05-01

Full Text Available Mateusz Hinzmann,1 Slawomir Jaworski,1 Marta Kutwin,1 Joanna Jagiello,2 Rafal Kozinski,2 Mateusz Wierzbicki,1 Marta Grodzik,1 Ludwika Lipinska,2 Ewa Sawosz,1 Andrè Chwalibog31Division of Nanobiotechnology, Warsaw University of Life Sciences, 2Institute of Electronic Materials Technology, Warsaw, Poland; 3Department of Veterinary Clinical and Animal Sciences, University of Copenhagen, Copenhagen, DenmarkAbstract: The carbon-based nanomaterial family consists of nanoparticles containing allotropes of carbon, which may have a number of interactions with biological systems. The objective of this study was to evaluate the toxicity of nanoparticles comprised of pristine graphene, reduced graphene oxide, graphene oxide, graphite, and ultradispersed detonation diamond in a U87 cell line. The scope of the work consisted of structural analysis of the nanoparticles using transmission electron microscopy, evaluation of cell morphology, and assessment of cell viability by Trypan blue assay and level of DNA fragmentation of U87 cells after 24 hours of incubation with 50 µg/mL carbon nanoparticles. DNA fragmentation was studied using single-cell gel electrophoresis. Incubation with nanoparticles containing the allotropes of carbon did not alter the morphology of the U87 cancer cells. However, incubation with pristine graphene and reduced graphene oxide led to a significant decrease in cell viability, whereas incubation with graphene oxide, graphite, and ultradispersed detonation diamond led to a smaller decrease in cell viability. The results of a comet assay demonstrated that pristine graphene, reduced graphene oxide, graphite, and ultradispersed detonation diamond caused DNA damage and were therefore genotoxic in U87 cells, whereas graphene oxide was not.Keywords: nanostructures, graphene, graphite, diamond, glioblastoma multiforme, geno toxicity

Adjustment of Cell-Type Composition Minimizes Systematic Bias in Blood DNA Methylation Profiles Derived by DNA Collection Protocols.

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Yuh Shiwa

Full Text Available Differences in DNA collection protocols may be a potential confounder in epigenome-wide association studies (EWAS using a large number of blood specimens from multiple biobanks and/or cohorts. Here we show that pre-analytical procedures involved in DNA collection can induce systematic bias in the DNA methylation profiles of blood cells that can be adjusted by cell-type composition variables. In Experiment 1, whole blood from 16 volunteers was collected to examine the effect of a 24 h storage period at 4°C on DNA methylation profiles as measured using the Infinium HumanMethylation450 BeadChip array. Our statistical analysis showed that the P-value distribution of more than 450,000 CpG sites was similar to the theoretical distribution (in quantile-quantile plot, λ = 1.03 when comparing two control replicates, which was remarkably deviated from the theoretical distribution (λ = 1.50 when comparing control and storage conditions. We then considered cell-type composition as a possible cause of the observed bias in DNA methylation profiles and found that the bias associated with the cold storage condition was largely decreased (λ adjusted = 1.14 by taking into account a cell-type composition variable. As such, we compared four respective sample collection protocols used in large-scale Japanese biobanks or cohorts as well as two control replicates. Systematic biases in DNA methylation profiles were observed between control and three of four protocols without adjustment of cell-type composition (λ = 1.12-1.45 and no remarkable biases were seen after adjusting for cell-type composition in all four protocols (λ adjusted = 1.00-1.17. These results revealed important implications for comparing DNA methylation profiles between blood specimens from different sources and may lead to discovery of disease-associated DNA methylation markers and the development of DNA methylation profile-based predictive risk models.

Application of a Tsunami Warning Message Metric to refine NOAA NWS Tsunami Warning Messages

Science.gov (United States)

Gregg, C. E.; Johnston, D.; Sorensen, J.; Whitmore, P.

2013-12-01

In 2010, the U.S. National Weather Service (NWS) funded a three year project to integrate social science into their Tsunami Program. One of three primary requirements of the grant was to make improvements to tsunami warning messages of the NWS' two Tsunami Warning Centers- the West Coast/Alaska Tsunami Warning Center (WCATWC) in Palmer, Alaska and the Pacific Tsunami Warning Center (PTWC) in Ewa Beach, Hawaii. We conducted focus group meetings with a purposive sample of local, state and Federal stakeholders and emergency managers in six states (AK, WA, OR, CA, HI and NC) and two US Territories (US Virgin Islands and American Samoa) to qualitatively asses information needs in tsunami warning messages using WCATWC tsunami messages for the March 2011 Tohoku earthquake and tsunami event. We also reviewed research literature on behavioral response to warnings to develop a tsunami warning message metric that could be used to guide revisions to tsunami warning messages of both warning centers. The message metric is divided into categories of Message Content, Style, Order and Formatting and Receiver Characteristics. A message is evaluated by cross-referencing the message with the operational definitions of metric factors. Findings are then used to guide revisions of the message until the characteristics of each factor are met. Using findings from this project and findings from a parallel NWS Warning Tiger Team study led by T. Nicolini, the WCATWC implemented the first of two phases of revisions to their warning messages in November 2012. A second phase of additional changes, which will fully implement the redesign of messages based on the metric, is in progress. The resulting messages will reflect current state-of-the-art knowledge on warning message effectiveness. Here we present the message metric; evidence-based rational for message factors; and examples of previous, existing and proposed messages.

Effect of a nonsurgical treatment program on the gait pattern of idiopathic toe walking: a case report

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Szopa A

2016-02-01

Full Text Available Andrzej Szopa,1 Małgorzata Domagalska-Szopa,2 Weronika Gallert-Kopyto,1 Wojciech Kiebzak,3 Ryszard Plinta4 1Department of Physiotherapy, 2Department of Medical Rehabilitation, School of Health Sciences, Medical University of Silesia, Katowice, 3Faculty of Health Sciences, Jan Kochanowski University, Kielce, 4Department of Adapted Physical Activity and Sport, School of Health Sciences, Medical University of Silesia, Katowice, Poland Background: Recent studies have reported many possibilities for the treatment of idiopathic toe walking (ITW; however, none of them have been sufficiently documented. The purpose of this case study was to document the evolution of the gait pattern of a child with severe ITW using the Gillette Gait Index before and after the third and sixth weeks, a nonsurgical treatment program and then every 3 months to 1 year from the start of the treatment. This is significant because the case study shows that a nonsurgical treatment program can be an alternative treatment method for children with severe ITW.Case description: The case study involved a 5-year-old boy diagnosed with severe ITW. An orthopedist recommended a surgical treatment, but his parents refused to provide consent.Intervention: The subject participated in a 12-week nonsurgical treatment program that used tone-inhibiting casts (TICs combined with physiotherapy based on neurodevelopmental treatment principles. The treatment protocol included the following: 1 precast preparation; 2 TICs with treatment; and 3 post-cast treatment to improve the gait pattern.Outcomes: After treatment with TICs, the range of motion of ankle dorsiflexion during stance had increased, resulting in an almost normalized gait. The patient stopped toe walking for at least 1 year.Discussion: This study demonstrates that nonsurgical treatment should be considered first, with surgical options reserved for resistant cases; however, further research is required given the current lack of knowledge

A Clinical Reasoning Tool for Virtual Patients: Design-Based Research Study.

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Hege, Inga; Kononowicz, Andrzej A; Adler, Martin

2017-11-02

feedback mechanisms and learning analytics algorithms. ©Inga Hege, Andrzej A Kononowicz, Martin Adler. Originally published in JMIR Medical Education (http://mededu.jmir.org), 02.11.2017.

The link between weight shift asymmetry and gait disturbances in chronic hemiparetic stroke patients

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Szopa A

2017-12-01

Full Text Available Andrzej Szopa,1 Małgorzata Domagalska-Szopa,2 Anetta Lasek-Bal,3 Amadeusz Żak3 1Department of Physiotherapy, 2Department of Medical Rehabilitation, School of Health Sciences in Katowice, 3Department of Neurology, Professor Leszek Giec Upper Silesian Medical Centre, Medical University of Silesia, Katowice, Poland Introduction: While the asymmetry of body posture and the asymmetrical nature of hemiparetic gait in poststroke (PS patients are well documented, the role of weight shift asymmetry in gait disorders after stroke remains unclear. Objective: We examined the association of weight-bearing asymmetry (WBA between paretic and nonparetic lower limbs during quiet standing with the degree of deviation of hemiplegic gait from normal gait evaluated by the Gillette Gait Index (GGI incorporating 16 distinct clinically important kinematic and temporal parameters in chronic PS patients.Participants and methods: Twenty-two ambulatory patients with chronic stroke aged between 50 and 75 years were included in this study. Fourteen patients had hemiparesis on the nondominant side and 8 on the dominant side. The mean time PS was 2 years and 6 months. The reference group consisted of 22 students from the University of the Third Age presenting no neurological disorders. The examination consisted of posturographic weight-bearing (WB distribution and 3-dimensional gait analyses.Results: A significant positive relationship between WBA and GGI was revealed. Moreover, we observed a significant negative association between WBA and paretic step length and walking speed. With regard to kinematic data, the range of motion of knee flexion and peak dorsiflexion in the swing phase of the paretic leg were significantly negatively associated with WBA.Conclusion: Although further research is needed to determine a causal link between postural control asymmetry and gait disturbance in hemiplegics, our findings support the inclusion of WB measurements between paretic and

Department of Nuclear Reactions: Overview

International Nuclear Information System (INIS)

Rusek, K.

2004-01-01

Full text: In spite of reduced personnel the number of papers published and in press exceeded fifty, almost ten more than a year ago. Another good sign is the growing number of PhD students. The following short reports cover the three major domains of our scientific activities: nuclear, material and atomic physics. Nuclear physics: The structure of light nuclei was investigated, and studies of nuclear reactions induced by heavy ions were performed including experiments at the Heavy Ion Laboratory of Warsaw University. The experiments were carried out in collaboration with scientists from the Institute of Nuclear Research from Kiev, Ukraine. Proton induced reactions on zirconium were investigated theoretically by means of a multistep-direct model extended for the unbound particle - hole states. Good agreement with the experimental data was achieved. Isospin effects in multifragmentation of relativistic heavy ions were studied by the ALADIN Collaboration. Elements of a new generation detector PANDA were tested experimentally using a proton beam provided by the C-30 compact cyclotron at Swierk. Evidence of a narrow baryon state was found in a quasi - real photoproduction on the deuterium target by the HERMES Collaboration. Atomic physics: Ionisation of selected heavy elements by sulphur ions was investigated in collaboration with the Swietokrzyska Academy, Kielce. Materials research: Hydrogen release from ultrahigh molecular weight polythene was investigated by means of an α - particle beam from the Van de Graaff accelerator of our Department. Last but not least, many of our colleagues have been involved in education. Lectures on nuclear physics, accelerators, detectors used in nuclear research as well as nuclear methods applied in solid state studies for students from many high schools of Warsaw and for students of Warsaw University were given by Dr. Andrzej Korman and Dr. Lech Nowicki. Also, our Department made a significant contribution to the 7 th Science

Relationships between components of emotional intelligence and physical pain in alcohol-dependent patients

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Kopera M

2017-07-01

Full Text Available Maciej Kopera,1 Kirk J Brower,2 Hubert Suszek,3 Andrzej Jakubczyk,1 Sylwia Fudalej,1 Aleksandra Krasowska,1 Anna Klimkiewicz,1 Marcin Wojnar1,2 1Department of Psychiatry, Medical University of Warsaw, Warsaw, Poland; 2Department of Psychiatry, Addiction Research Center, University of Michigan, Ann Arbor, MI, USA; 3Department of Psychology, University of Warsaw, Warsaw, Poland Purpose: Chronic pain is a significant comorbidity in individuals with alcohol dependence (AD. Emotional processing deficits are a substantial component of both AD and chronic pain. The aim of this study was to analyze the interrelations between components of emotional intelligence and self-reported pain severity in AD patients. Patients and methods: A sample of 103 participants was recruited from an alcohol treatment center in Warsaw, Poland. Information concerning pain level in the last 4 weeks, demographics, severity of current anxiety and depressive symptoms, as well as neuroticism was obtained. The study sample was divided into “mild or no pain” and “moderate or greater pain” groups. Results: In the logistic regression model, across a set of sociodemographic, psychological, and clinical factors, higher emotion regulation and higher education predicted lower severity, whereas increased levels of anxiety predicted higher severity of self-reported pain during the previous 4 weeks. When the mediation models looking at the association between current severity of anxiety and depressive symptoms and pain severity with the mediating role of emotion regulation were tested, emotion regulation appeared to fully mediate the relationship between depression severity and pain, and partially the relationship between anxiety severity and pain. Conclusion: The current findings extend previous results indicating that emotion regulation deficits are related to self-reported pain in AD subjects. Comprehensive strategies focusing on the improvement of mood regulation skills might be

Physical and mental health aspects of elderly in social care in Poland

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Dobrzyn-Matusiak D

2014-10-01

Full Text Available Dorota Dobrzyn-Matusiak,1 Czeslaw Marcisz,2 Ewelina Bąk,3 Halina Kulik,1 Ewa Marcisz4 1Department of Nursing Propaedeutics, 2Department of Gerontology and Geriatric Nursing, School of Health Care, Medical University of Silesia, Katowice, Poland; 3Faculty of Health Sciences, University of Bielsko-Biała, Bielsko-Biała, Poland; 4Department of Anxiety Disorders, Hospital of Ministry of Internal Affairs, Katowice, Poland Background: The objective of the study was to evaluate health aspects in elderly individuals in social, institutional, and home care in Poland.Methods: A total of 300 elderly individuals in care in Poland were included in the study. The subjects were divided into three groups: residents of long-term care institutions (group I, residents of adult day-care homes (group II, and community-dwelling subjects (group III. Each group consisted of 100 subjects. Questionnaires evaluating the following physical and mental dimensions of health were used: SF-36 Health Survey, basic activities of daily living, instrumental activities of daily living, Geriatric Depression Scale, and Mini–mental state examination.Results: It was found that the health aspects of the elderly varied depending on whether care was provided in an institutionalized or a home environment, and the lowest health status was found in the elderly receiving in-home care. Furthermore, home-based elderly indicated significant limitations in performing basic activities of daily living and instrumental activities of daily living, as well as a higher prevalence of depression and cognitive impairment.Conclusion: The elderly in long-term institutionalized care, both in a residential home and adult day-care homes, were characterized by a better physical and mental health status than those receiving in-home care. It seemed that worse health status, including the more frequent depression occurrence and cognitive function disorders in the elderly using the nursing care at their homes

Polish Literature of the Holocaust. The First Instalment: 1939-1968

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Katarzyna Kuczyńska-Koschany

2015-01-01

Full Text Available The text is a critical attempt discussing the compendium Literatura polska wobec Zagłady, (“Polish Literature in the Face of the Holocaust” edited and published by three prominent scholarly experts on the subject: Sławomir Buryła, Dorota Krawczyńska and Jacek Leociak. This is the first of the three volumes of the series Reprezentacje Zagłady w kulturze polskiej (“Representations of the Holocaust in Polish Culture” – an endeavour which is imposing already in its first instalment concerning the years 1939-1968. The time frame of the abovementioned volume is marked by the date of the beginning of World War II (1939, resulting in the Holocaust of the Jews of Europe, and a “dry pogrom”, that is was the anti-Semitic campaign in Poland in 1968 (the campaign itself and its writings shall be examined in the following volume. A comprehensive and very carefully prepared monograph has been divided into two fundamental parts: concerning the literature reacting to the Holocaust conducted by Nazi Germany during the war (1939-1945 and discussing the literary echoes of that genocide in the years 1945-1968. The study and invaluable interpretational effort have been focused on personal document literature (Marta Janczewska, Jacek Leociak, the prose (Sławomir Buryła, Dorota Krawczyńska, the poetry (Piotr Matywiecki and the press (Ewa Koźmińska-Frejlak. A separate chapter has been devoted to a the “global text”, i.e., Archiwum Ringelbluma (“Ringelblum’s Archives”. Highly appreciating the entire volume as well as its individual fragments, recalling fundamental considerations and the ones concerning details, finally, proposing small corrections and pointing to minor shortcomings, the author of the critical review suggests the use of the formula “Polish literature of the Holocaust” (analogous to the formula coined by Grzegorz Niziołek “Polish theatre of the Holocaust” as the one principally necessary to be contrasted with the

[Moral and religious issues in health care].

Science.gov (United States)

Necek, Robert

2012-01-01

The paper summarises the moral and spiritual factors important in care for sick people. Medical care is one of the ancient forms of our activity as humans, expounding care for other people's well-being. The moral aspect of medical care is deeply rooted in constant daily interaction between the patient and the doctor aiming at easing symptoms, support, help, prevention and defense. Such teleological orientation of medicine is, according to John Paul II, made possible not so much by technology but by physician's conscience, wisdom and unlimited honesty. This is where ethics is needed to regulate that particular relation. This ethics stems from Christian morality, which raises our role as humans to that of guardians of dignity of another human being. Man is indeed the measure of all things, and this becomes the context for all relations including man's relation to God, but also relation of God to man. Thus, human dignity assumes the status of unconditional natural rule, inherently forestalling all legal arrangements. The morality of health care requires holistic approach, including care for body, mind, social interaction and spiritual needs. Only then, as explained by dr Ewa Kucharska, is it possible to answer patient's all needs. The moral side of the therapeutic contract bounds the doctor and the patient, alike. From this point of view, it is immoral not to cooperate with physicians in their strife for the preservation of health and life itself. Self negligence or active self harm (drugs, alcohol abuse, HIV/AIDS) are the utmost examples of such dishonesty. Finally, the imperative to bring hope and faith to the suffering, vests special importance in hospital chaplains, who bring good word, but most importantly the sacrament to those in need. The prayer in turn may evoke strong hope for cure, capable of supporting both soul and body. The suffering of man cannot be understood on rational grounds. It requires acceptance, and, above all, it requires faith. And this

In vitro and in vivo effects of graphene oxide and reduced graphene oxide on glioblastoma

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Jaworski S

2015-02-01

Full Text Available Sławomir Jaworski,1 Ewa Sawosz,1 Marta Kutwin,1 Mateusz Wierzbicki,1 Mateusz Hinzmann,1 Marta Grodzik,1 Anna Winnicka,2 Ludwika Lipinska,3 Karolina Włodyga,1 Andrè Chwalibog41Warsaw University of Life Science, Faculty of Animal Science, Division of Biotechnology and Biochemistry of Nutrition, 2Department of Pathology and Veterinary Diagnostics, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, 3Institute of Electronic Materials Technology, Warsaw, Poland; 4University of Copenhagen, Department of Veterinary Clinical and Animal Sciences, Copenhagen, DenmarkAbstract: Graphene and its related counterparts are considered the future of advanced nanomaterials owing to their exemplary properties. However, information about their toxicity and biocompatibility is limited. The objective of this study is to evaluate the toxicity of graphene oxide (GO and reduced graphene oxide (rGO platelets, using U87 and U118 glioma cell lines for an in vitro model and U87 tumors cultured on chicken embryo chorioallantoic membrane for an in vivo model. The in vitro investigation consisted of structural analysis of GO and rGO platelets using transmission elec­tron microscopy, evaluation of cell morphology and ultrastructure, assessment of cell viability by XTT assay, and investigation of cell proliferation by BrdU assay. Toxicity in U87 glioma tumors was evaluated by calculation of weight and volume of tumors and analyses of ultrastructure, histology, and protein expression. The in vitro results indicate that GO and rGO enter glioma cells and have different cytotoxicity. Both types of platelets reduced cell viability and proliferation with increasing doses, but rGO was more toxic than GO. The mass and volume of tumors were reduced in vivo after injection of GO and rGO. Moreover, the level of apoptotic markers increased in rGO-treated tumors. We show that rGO induces cell death mostly through apoptosis, indicating the potential applicability of

Eerder anders as elders: Gerrie Snyman se bydrae in die konteks van die Gereformeerde teologie

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Hans J.M. van Deventer

2010-03-01

Full Text Available Rather different than elsewhere: Gerrie Snyman�s contribution in the context of Reformed theology Prof Gerrie Snyman�s book Om die Bybel anders te lees: �n etiek van Bybellees (2007 attracted considerable attention in Afrikaans-speaking reformed circles in South Africa. In this article, some of the responses to and reviews of the book are studied in order to assess the publication�s impact. Moreover, the article aims to determine whether the book will contribute to future reflections and discussions on the use of the Bible in this context. It is concluded that the preferred method of interpretation in the Reformed Church in South Africa calls for a thorough revision. The so-called �grammatical-historical method� of interpretation can no longer be regarded as the most appropriate and sole �Reformed method� of interpretation.�--- Abstract translated into Sipedi ---Go fapana le t�e dingwe: seabe sa Gerrie Snyman go teologie ya RefomoPuku ya Profesa Gerrie Snyman, Om die Bybel anders te lees: �n Etiek van Bybellees (2007, e gogile �edi ye kgolo ya maloko a kereke ya Refomo mo Afrika-Borwa(RCSA/GKSA. Mo pampiring ye re ithuta t�e dingwe t�a dikarabo le ditshekatsheko t�a puku ye go ela khuet�o ya yona. Go feta fao, pampiri ye e nepile go bona ge e ba puku ye e tlo ba le seabe go dikakanyo le dipoledi�ano mabapi le t�homi�o ya Beibele ditabeng t�a mohuta wo. Re ruma ka go re, mokgwa wa tshekatsheko ya Bibele wa Kereke ya Refomo mo Afrika-Borwa o hloka go lekodi�i�wa le go boelet�wa. Mokgwa wa go hlatholla Bibele ka go sekaseka popopolelo(gramatika le histori ya tlholego ya yona, o ka se sa t�ewa e le wona wa maleba o nno�i wa tshekatsheko goba go ba wona �Mokgwa wa Refomo� wa go fetleka Bibele.--- End of translation ---

Department of Nuclear Reactions: Overview

International Nuclear Information System (INIS)

Rusek, K.

1998-01-01

(full text) During the last year our activities were spread over the three major domains: nuclear, atomic and material physics. The nuclear physics experimental programme covered a broad range of nuclear reactions induced by light and heavy ions. New experiments were performed at the compact C-30 cyclotron at Swierk, at University of Jyvaeskylae, GSI Darmstadt, LN Saturne. Prospects for future experiments on nucleon structure at Forschungszentrum Juelich were open. The collaboration with INR Kiev was tightened and work was done in order to prepare experiments at the C-200 heavy ion cyclotron in Warsaw. An effort to install the ion guide isotope separator on line (IGISOL) at the C-200 cyclotron has also to be mentioned A half a year stay of Dr. Nicholas Keeley in the Department, who received The Royal Society/Polish Academy of Science grant, resulted in many interesting results on breakup of light nuclei. Details can be found in the short abstracts presented in this report. As far as atomic physics is concerned, the activity of a group lead by Prof. Marian Jaskola yielded various new results. The experiments were performed at the University of Erlangen, in close collaboration with the Pedagogical University in Kielce and the University of Basel. Fast neutrons generated in the 3 H(d,n) 4 He reaction induced by the 2 MeV deuteron beam from the Van der Graaff accelerator at the Department were used to calibrate solid state-nuclear-track detectors. This was a very good year for material physics research: Jan Kaczanowski and Slawomir Kwiatkawski received Ph.D. degrees based on dissertation research performed in the material physics research programme, while Pawel Kolodziej completed his MSc. thesis in collaboration with the Institute of Electronic Materials Technology in Warsaw, Research Center Karlsruhe, University of Jena and CSNSM Orsay many results were obtained. Lech Nowicki and Prof. Andrzej Turos were awarded by the Director of the IPJ prizes for their scientific

The influence of frailty syndrome on acceptance of illness in elderly patients with chronic obstructive pulmonary disease

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Uchmanowicz I

2016-09-01

Full Text Available Izabella Uchmanowicz,1 Beata Jankowska-Polanska,1 Mariusz Chabowski,2 Bartosz Uchmanowicz,1 Andrzej M Fal3 1Department of Clinical Nursing, Faculty of Health Science, Wroclaw Medical University, 2Division of Nursing in Surgical Procedures, Department of Clinical Nursing, Faculty of Health Science, Wroclaw Medical University, 3Department of Healthcare Organisation and Economics, National Institute of Public Health, National Institute of Hygiene, Warsaw, Poland Abstract: COPD is one of the most debilitating diseases. Frailty syndrome and advanced age may decrease the acceptance of illness, quality of life, and worsen health conditions in these patients, as well as lead to an increase in health care expenses. The aim of the study was to assess how the level of frailty affects the acceptance of illness in elderly patients with COPD. We also aimed to evaluate the associations between sociodemographic and clinical factors and the level of acceptance of illness, anxiety, and frailty in this group of patients. The study included 102 COPD patients with a mean age of 63.2 (standard deviation =6.5 years and grades I (3%, II (37%, III (52%, and IV (8% by Global Initiative for Chronic Obstructive Lung Disease. The Polish versions of the Acceptance of Illness Scale and Tilburg frailty indicator were used. Frailty syndrome was found in 77 (75.5% patients, with an average score of 7.42 (standard deviation =2.24. Coexisting diseases such as hypertension (46.07%, coronary artery disease (32.35%, heart failure (28.43%, diabetes (18.63%, and heart arrhythmia (9.8% were found among the subjects. The overall level of acceptance of illness was 20.6 (standard deviation =7.62. A lower level of acceptance of illness was associated with a higher level of frailty, especially in the physical and social domain. Elderly patients with severe COPD are more prone to frailty and decreased acceptance of their disease in comparison to patients with other chronic diseases

Assessment of selected quality fields of nursing care in neurosurgical wards: a prospective study of 530 people – multicenter studies

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Ślusarz R

2014-08-01

Full Text Available Robert Ślusarz,1 Monika Biercewicz,2 Ewa Barczykowska,3 Beata Haor,4 Mariola Głowacka5 1Neurological and Neurosurgical Nursing Department, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, 2Clinic of Geriatrics, 3Nursing Department, Collegium Medicum, Nicolaus Copernicus University, Torun, 4Faculty of Health Science, University of Humanities and Economics in Wloclawek, Wloclawek, 5Institute of Health Sciences, State School of Higher Professional Education in Plock, Plock, Poland Background: One of the elements influencing the assessment of nursing care quality is the assessment of the nurse’s functions that determine the nurse’s particular tasks. The aim of this work was to assess selected tasks involved in the nurse’s caring function, which influence nursing care quality on neurosurgical wards, on the basis of patients’ and nursing staff’s opinions.Materials and methods: The research was carried out on neurosurgical wards in Poland on a group of 455 patients and 75 nurses. In order to assess nursing care quality, an author’s original questionnaire (Questionnaire – Patient Satisfaction was used.Results: Statistically significant differences concerned particular groups (both patients and nurses in the assessment of selected issues: providing information about performed activities and operations (P=0.000 and P=0.040, respecting personal dignity and assuring discretion during the operations (P=0.000 and P=0.001, speed of response to patient’s requests (P=0.000 and P=0.000, time availability of nurses for the patient (P=0.000 and P=0.000, providing information about further self-care at home (P=0.032, P=0.008, and nurses’ attitude (kindness, courtesy, tenderness, care to patients (patient’s assessment only P=0.000.Conclusion: Selected tasks in the field of the caring function of nurses were assessed differently by particular groups. There were no statistically significant differences in the assessment of particular

International Conference on Microtechnology and Thermal Problems in Electronics (MicroTherm'2015) and International Conference on Smart Engineering of New Materials (SENM'2015)

International Nuclear Information System (INIS)

2016-01-01

. The latter gave an opportunity for students and young researchers to present their first achievements in the field of science. Next Joint Event combining MicroTherm and SENM Conferences is going to be held in June 2017, traditionally in Lodz – beautiful, post-industrial city located in the centre of Poland. For further details, please see the Duoconference web site www.semtherm.eu. Please, feel invited. Ewa Raj and Katarzyna Znajdek Editors (paper)

Effect of Nordic Walking training on iron metabolism in elderly women

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Kortas J

2015-11-01

Full Text Available Jakub Kortas,1 Katarzyna Prusik,2 Damian Flis,3 Krzysztof Prusik,1 Ewa Ziemann,4 Neil Leaver,5 Jedrzej Antosiewicz6 1Department of Recreation and Tourism, Gdansk University of Physical Education and Sport, Gdansk, Poland; 2Department of Biomedical Basis of Health, Gdansk University of Physical Education and Sport, Gdansk, Poland; 3Department of Bioenergetics and Physiology of Exercise, Medical University of Gdansk, Gdansk, Poland; 4Department of Physiology and Pharmacology, Gdansk University of Physical Education and Sport, Gdansk, Poland; 5The Immunosuppression monitoring service (IMS Laboratory, Royal Brompton & Harefield NHS Foundation Trust, Heart Science Centre, Harefield Hospital, Harefield, UK; 6Department of Biochemistry, Gdansk University of Physical Education and Sport, Gdansk, Poland Background: Despite several, well-documented pro-healthy effects of regular physical training, its influence on body iron stores in elderly people remains unknown. At the same time, body iron accumulation is associated with high risk of different morbidities.Purpose: We hypothesized that Nordic Walking training would result in pro-healthy changes in an elderly group of subjects by reducing body iron stores via shifts in iron metabolism-regulating proteins.Methods: Thirty-seven women aged 67.7±5.3 years participated in this study. They underwent 32 weeks of training, 1-hour sessions three times a week, between October 2012 and May 2013. Fitness level, blood morphology, CRP, vitamin D, ferritin, hepcidin, and soluble Hjv were assessed before and after the training.Results: The training program caused a significant decrease in ferritin, which serves as a good marker of body iron stores. Simultaneously, the physical cardiorespiratory fitness had improved. Furthermore, blood hepcidin was positively correlated with the ferritin concentration after the training. The concentration of blood CRP dropped, but the change was nonsignificant. The applied training

Anxiety Associated Increased CpG Methylation in the Promoter of Asb1: A Translational Approach Evidenced by Epidemiological and Clinical Studies and a Murine Model.

Science.gov (United States)

Emeny, Rebecca T; Baumert, Jens; Zannas, Anthony S; Kunze, Sonja; Wahl, Simone; Iurato, Stella; Arloth, Janine; Erhardt, Angelika; Balsevich, Georgia; Schmidt, Mathias V; Weber, Peter; Kretschmer, Anja; Pfeiffer, Liliane; Kruse, Johannes; Strauch, Konstantin; Roden, Michael; Herder, Christian; Koenig, Wolfgang; Gieger, Christian; Waldenberger, Melanie; Peters, Annette; Binder, Elisabeth B; Ladwig, Karl-Heinz

2018-01-01

Epigenetic regulation in anxiety is suggested, but evidence from large studies is needed. We conducted an epigenome-wide association study (EWAS) on anxiety in a population-based cohort and validated our finding in a clinical cohort as well as a murine model. In the KORA cohort, participants (n=1522, age 32-72 years) were administered the Generalized Anxiety Disorder (GAD-7) instrument, whole blood DNA methylation was measured (Illumina 450K BeadChip), and circulating levels of hs-CRP and IL-18 were assessed in the association between anxiety and methylation. DNA methylation was measured using the same instrument in a study of patients with anxiety disorders recruited at the Max Planck Institute of Psychiatry (MPIP, 131 non-medicated cases and 169 controls). To expand our mechanistic understanding, these findings were reverse translated in a mouse model of acute social defeat stress. In the KORA study, participants were classified according to mild, moderate, or severe levels of anxiety (29.4%/6.0%/1.5%, respectively). Severe anxiety was associated with 48.5% increased methylation at a single CpG site (cg12701571) located in the promoter of the gene encoding Asb1 (β-coefficient=0.56 standard error (SE)=0.10, p (Bonferroni)=0.005), a protein hypothetically involved in regulation of cytokine signaling. An interaction between IL-18 and severe anxiety with methylation of this CpG cite showed a tendency towards significance in the total population (p=0.083) and a significant interaction among women (p=0.014). Methylation of the same CpG was positively associated with Panic and Agoraphobia scale (PAS) scores (β=0.005, SE=0.002, p=0.021, n=131) among cases in the MPIP study. In a murine model of acute social defeat stress, Asb1 gene expression was significantly upregulated in a tissue-specific manner (p=0.006), which correlated with upregulation of the neuroimmunomodulating cytokine interleukin 1 beta. Our findings suggest epigenetic regulation of the stress

As estratégias operatórias e a gestão da informação no trabalho de enfermagem, no contexto hospitalar Las estrategias operatórias y la gestión de la información del trabajo de enfermeros en el entorno hospitalario The operatory strategies and information process of the nursing work in hospital context

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Diana Lúcia Moura Pinho

2003-03-01

Full Text Available O estudo analisa as estratégias operatórias de gestão da informação, utilizadas pelos enfermeiros no contexto hospitalar para regular o trabalho. O quadro teórico inscreve-se no campo da ergonomia, articulando conceitos de regulação da atividade, representações para e na ação. A Análise Ergonômica do Trabalho - AET orientou a coleta de dados. Os resultados demonstram que as estratégias adotadas pelos enfermeiros apóiam-se na utilização de um recurso informal externo (anotações pessoais que visa, sobretudo, reduzir a carga mental de trabalho e garantir a fiabilidade de suas ações.El presente estudio investiga las estrategias operatorias en la gestión de la información utilizadas por los enfermeros, en el entorno hospitalario, para regular su trabajo. El cuadro teórico de referencia adoptado se incluye en el campo de la ergonomía articulando conceptos de conducta de regulación y representaciones para y en la acción. El " Análisis Ergonómico del Trabajo - AET " orientó la recolección de los datos. Los resultados demuestran que las estrategias cognitivas adoptadas por los enfermeros en la gestión de la información se apoya en la elaboración de anotaciones personales, con el objetivo, sobretodo, de reducir la carga de trabajo mental y garantizar la fiabilidad de sus acciones.The paper examines the relationship between operatory strategies and information process used by nurses, in hospital context, in order to regulate their ongoing activities. As a conceptual framework, a cognitive ergonomics model was adopted, linking concepts of work regulation and representation to action. The Ergonomics Work Analyses tool (EWA was used to collect data. The results show that the cognitive strategies used by nurses, in the decision-making process, are based on their ongoing activities as in the preparation of personal notes, aiming, in particular, at reducing their mental workload and assuring the viability of their actions.

Depressogenic medications and other risk factors for depression among Polish patients with epilepsy

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Bosak M

2015-09-01

Full Text Available Magdalena Bosak,1 Wojciech Turaj,1 Dominika Dudek,2 Marcin Siwek,2 Andrzej Szczudlik1 1Department of Neurology, 2Department of Psychiatry, Jagiellonian University Medical College, Krakow, Poland Purpose: The aim of this study was to assess the prevalence of depression among patients with epilepsy and to establish the risk factors of depression in that group, with special focus on the use of potentially depressogenic medications. Patients and methods: We studied 289 consecutive patients who visited epilepsy outpatient clinic (University Hospital of Krakow and met inclusion criteria. All patients were screened with Beck Depression Inventory (BDI, and those with BDI score ≥12 were further evaluated by a psychiatrist. Results: Mean age of patients was 35.7 years, and mean duration of epilepsy was 14.7 years. Idiopathic generalized epilepsy was diagnosed in 63 patients (21.8%, focal epilepsy was found in 189 subjects (65.4%, and unclassified epilepsy was diagnosed in 37 patients (12.8%. Frequent seizures (>1 per month were reported in 107 patients (37.0%. Thirty-five patients (12.1% reported an ongoing treatment with one or more of the predefined potentially depressogenic medication (ß-blockers, combined estrogen and progestogen, corticosteroid, or flunarizine. In a group of 115 patients (39.8% who scored ≥12 points in BDI, depression was finally diagnosed in 84 subjects (29.1% after psychiatric evaluation. Only 20 of those patients (23.8% were treated with antidepressant. Independent variables associated with the diagnosis of depression in the logistic regression model included frequent seizures (odds ratio [OR] =2.43 [95% confidence interval, 95% CI =1.38–4.29], P=0.002, use of potentially depression-inducing medications (OR =3.33 [95% CI =1.50–7.39], P=0.003, age (OR =1.03 [95% CI =1.01–1.05] per year], P=0.005, and use of oxcarbazepine (OR =2.26 [95% CI =1.04–4.9], P=0.038. Conclusion: The prevalence of depression among consecutive

International Round Table “Tatar Materials in Polish Archives” (Warsaw, 31st March – 1st April, 2016

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M.M. Gibatdinov

2016-12-01

Full Text Available This article present a short report on the International round table “Tatar materials in Polish archives” organized in Warsaw on March 31 – April 1, 2016. Round table was a result of international scientific cooperation between Marjani Institute of History, Polish Academy of Sciences, University of Warsaw, Institute for Caucasian-, Tatar- and Turkestan Studies (ICATAT. It was a part of the long-term research project “Tatar Materials in Foreign Archives” carried out by the Marjani Institute of History in the framework of State Program of the Republic of Tatarstan “Preserving of Tatar Ethnical Identity (for years 2014–2016.” The following papers was presented on the round table: “On results of recent researches of Tatar materials in Polish archives” by Prof., Dr. Dariusz Kołodziejczyk, Director of the Institute of History, University of Warsaw; “The New Records of Old Heritage – Documents about Tatars from Regional and Private Archives in Polish-German Context”, by Dr. Mieste Hottop-Riecke, Director of ICATAT and Dr. Stephan Theilig, Director of Brandenburg-Preußen Museum Wustrau; “Maniere de Faire la Guerre des Tartares’ as Hybrid War in the Military Art of Crimean and Dobruja Tatars in the Early modern Time”, by Dr. Andrzej Gliwa, University of Warsaw, Department of History, Faculty Member; “Tatar Documents in Archives and Museums in Bialystok” by Dr. Artur Konopacki, Assistant Professor in Faculty of Pedagogy and Psychology, University of Bialystok; ”The first results of international research project ”Yazma Miras – Written Heritage” by Marat Gibatdinov. Participants of round table discussed a possible prospects for future cooperation in the field of researching and digitalizing of Tatar materials from Polish archives. During the conference the meetings with the representatives of Tatar community in Poland and Lithuania was organized, as well as the study visits to the Tatar Mosque and Tatar

Department of Nuclear Reactions: Overview

International Nuclear Information System (INIS)

Rusek, K.

2003-01-01

response of the detectors to those ions was investigated. The ion channelling method was applied to investigate the transformation of the structural defects in InGaAs and InGaAsP layers. - Education: Lectures on nuclear physics, accelerators, detectors used in nuclear research as well as on nuclear methods used in solid state studies for students from Warsaw High Schools and for students of Warsaw University were given by Dr. Andrzej Korman and Dr. Lech Nowicki. Also, our Department made contributions to the Scientific Picnic and the Science Festival, events organized each year for the general public. (author)

BIOGRAMY POLSKICH MYŚLICIELI NIERUCHOMOŚCI

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Edyta Łazarowicz

2009-11-01

Full Text Available Fragment artykułu: [b]Andrzej Bieniek[/b] (1895-1944, doktor, urodził się 17 października 1895 r. w Bratucicach (powiat Bochnia, rozstrzelany 26 lipca 1944 roku w ruinach getta w Warszawie. (...Doktor A. Bieniek zajmował się głównie problemami organizacji księgowości w przedsiębiorstwach oraz rachunkiem kosztów. Był autorem m.in. następujących publikacji: Polska metoda księgowości oparta na ekonomicznym systemie Taylora (Biblioteka Państwowej Szkoły Handlowej Męskiej w Łodzi, Łódź 1927, Kantor wzorowy w szkołach handlowych (Biblioteka Państwowej Szkoły Handlowej Męskiej w Łodzi, Warszawa-Łódź 1928, Księgowość w przedsiębiorstwach przemysłowych (Biblioteka Rady Głównej Zrzeszeń Księgowych i Rzeczoznawców Księgowości w Polsce, Warszawa 1935, Zasady inwentaryzacji i bilansowania (Związek Księgowych w Polsce, Warszawa 1936, Organizacja rachunkowości w przedsiębiorstwach przemysłowych ((Związek Księgowych w Polsce, Warszawa 1939, Zasady analizy bilansów (Stowarzyszenie Nauczycieli Szkół Zawodowych. Sekcja Główna Handlowa, Warszawa 1939. [b]Zygmunt Stefan Kossut[/b] (1922–1984 profesor doktor habilitowany, syn Wiktora Kossuta i Henryki Serafin, urodził się 16 kwietnia 1922 r. (.. Do dzisiaj znane jest profesjonalistom zdanie E. Terebuchy, że „on pierwszy (Z. Kossut – M.G. przeorał ugór w naszej nauce rachunkowości, wykonując próbę sformułowania nowych poglądów na metody badawcze w dziedzinie teorii rachunkowości.” [b]Kazimierz Sowa[/b] (1915–1972, profesor nadzwyczajny, doktor, urodził się 2 października 1915 roku w Krakowie w rodzinie chłopskiej, zmarł 17 grudnia 1972 r. w Krakowie. Był żonaty, bezdzietny. (... Okres pracy zawodowej Kazimiera Sowy (1938–1972 był bardzo zróżnicowany i przebiegał wielotorowo. Była to praca naukowo-dydaktyczna w szkolnictwie wyższym, praca redakcyjno-popularyzatorska, organizacyjno-kierownicza w Stowarzyszeniu Księgowych w

Encapsulation technology of MR6 spent fuel and quality analysis of the EK-10 and WWR-SM spent fuel stored more than 30 years in wet conditions

Energy Technology Data Exchange (ETDEWEB)

Borek-Kruszewska, E.; Bykowski, W.; Chwaszczewski, S.; Czajkowski, W.; Madry, M. [Institute of Atomic Energy, Otwock -Swierk (Poland)

2002-07-01

The research reactor MARIA has been in operation for more than twenty years and all the spent fuel assemblies used since the first commissioning of the reactor are stored in wet facility on site. The present paper deals with the spent fuel MR-6 encapsulation technology in MARIA reactor. The encapsulated spent MR-6 fuel will be stored under water in the same pool unless some other solution is available. The capsules made of stainless steel are capable to accommodate one MR-6 fuel assembly. The encapsulation process is performed in the hot cell by the MARIA reactor. The spent fuel having its leg cut off is loaded to the transport cylinder manually and next transferred to a trolley. The trolley is moving to a position directly below the entrance to the hot cell and the spent fuel is entering the hot cell. The spent fuel assembly is then put into the drying cell. Dried out spent fuel is moved into the capsule mounted on the grip of the machine. Next, the capsule lid is pressed in and welded. After the leak test and filling up with helium the capsule returns from the hot cell to the pool. The hermetic capsule is sunk back into the water and positioned in the separator . The results presented earlier show, that the limiting time of WWR-SM and Ek-10 type spent fuel residence in wet storage is about 40-45 years. Therefore, the systematic quality investigation of all Ek-10 fuel elements and WWR-SM fuel assemblies discharged from EWA reactor in the period of 1959-1969 was performed. Altogether, about 2500 Ek-10 fuel elements and 47 WWR-SM fuel assemblies were investigated. The results of these investigations are presented in the present work. The sipping test, visual investigation and ultrasonic techniques were used for that purpose. The radioactive isotope Cs-137 was used as the indicator of fission product release from the fuel assembly. Taking into account the value of Cs-137 release from damaged WWR-SM fuel assembly the criteria of damaged fuel assembly were proposed. It

Editorial

Directory of Open Access Journals (Sweden)

Mirosław Pawlak

2011-08-01

Full Text Available The current issue of Studies in Second Language Learning and Teaching brings together six contributions written by scholars from Poland and abroad which deal with a wide array of issues related to learning and teaching additional languages in different educational contexts. First, Weronika Szubko-Sitarek reports the findings of two experimental studies conducted within the lexical decision task paradigm which aimed to investigate the cognate facilitation effect in the process of recognizing words in a third language by Polish unbalanced trilinguals who, in addition to their mother tongue, were proficient in English and had variable command of German. In the next paper, Sane M. Yagi and Saleh Al-Salman make a strong case for the use of tracking software in writing pedagogy as a tool for providing invaluable insights into the process of composing texts, but also a method of stimulating reflection and promoting strategic learning. The research-based contributions by Ewa Waniek-Klimczak and Aleksandra Wach, in turn, shift the emphasis to sociolinguistic issues. The former presents the findings of a qualitative study which examined the acculturation patterns of three recent Polish immigrants to the United Kingdom, who were expert users of English, in relation to their formal and informal language learning experiences, while the latter uses questionnaire data obtained from a respectable sample of Polish-speaking English majors to shed light on their preferences concerning pronunciation norms based on the native-speaker model and the Lingua Franca Core. The last two papers included in this issue report the findings of studies exploring the role of anxiety in learning foreign language skills and subsystems. In the first of these, Christina Gkonou examines the interfaces between speaking and writing anxiety manifested by Greek learners of English as a foreign language in a private school setting and, in the second, Magdalena Szyszka taps the relationship

Prenatal Exposure to Maternal Cigarette Smoking and DNA Methylation: Epigenome-Wide Association in a Discovery Sample of Adolescents and Replication in an Independent Cohort at Birth through 17 Years of Age

Science.gov (United States)

Lee, Ken W.K.; Richmond, Rebecca; Hu, Pingzhao; French, Leon; Shin, Jean; Bourdon, Celine; Reischl, Eva; Waldenberger, Melanie; Zeilinger, Sonja; Gaunt, Tom; McArdle, Wendy; Ring, Susan; Woodward, Geoff; Bouchard, Luigi; Gaudet, Daniel; Smith, George Davey; Relton, Caroline; Paus, Tomas

2014-01-01

Background: Prenatal exposure to maternal cigarette smoking (prenatal smoke exposure) had been associated with altered DNA methylation (DNAm) at birth. Objective: We examined whether such alterations are present from birth through adolescence. Methods: We used the Infinium HumanMethylation450K BeadChip to search across 473,395 CpGs for differential DNAm associated with prenatal smoke exposure during adolescence in a discovery cohort (n = 132) and at birth, during childhood, and during adolescence in a replication cohort (n = 447). Results: In the discovery cohort, we found five CpGs in MYO1G (top-ranking CpG: cg12803068, p = 3.3 × 10–11) and CNTNAP2 (cg25949550, p = 4.0 × 10–9) to be differentially methylated between exposed and nonexposed individuals during adolescence. The CpGs in MYO1G and CNTNAP2 were associated, respectively, with higher and lower DNAm in exposed versus nonexposed adolescents. The same CpGs were differentially methylated at birth, during childhood, and during adolescence in the replication cohort. In both cohorts and at all developmental time points, the differential DNAm was in the same direction and of a similar magnitude, and was not altered appreciably by adjustment for current smoking by the participants or their parents. In addition, four of the five EWAS (epigenome-wide association study)–significant CpGs in the adolescent discovery cohort were also among the top sites of differential methylation in a previous birth cohort, and differential methylation of CpGs in CYP1A1, AHRR, and GFI1 observed in that study was also evident in our discovery cohort. Conclusions: Our findings suggest that modifications of DNAm associated with prenatal maternal smoking may persist in exposed offspring for many years—at least until adolescence. Citation: Lee KW, Richmond R, Hu P, French L, Shin J, Bourdon C, Reischl E, Waldenberger M, Zeilinger S, Gaunt T, McArdle W, Ring S, Woodward G, Bouchard L, Gaudet D, Davey Smith G, Relton C, Paus T

The role of international collaboration in knowledge development in creation of TSO

International Nuclear Information System (INIS)

Jackowski, Tomasz Marian; Skrzypek, Elena; Spirzewski, Michal

2014-01-01

National Centre for Nuclear Research has been created on September the 1 st 2011 by the decree of the Polish Government with a clear goal to form Technical Support Organization for Polish regulator and public administration. It was done by merging two institutes, the former Institute of Atomic Energy POLATOM and the former Andrzej Soltan Institute for Nuclear Studies, which worldwide reputation and successful research in various fields of nuclear power-related studies are well known. The fields of activity are widely focused on the nuclear physics, cosmology, electronics as well as detectors, accelerators, material research and many more. The main factor of National Center for Nuclear Research development was the participation in the European Structural Founds program ''Swierk Computing Centre'' from the beginning. In the frame of this particular program, the collaboration with the IAEA, NEA OECD, Euratom and research and TSO organizations from different countries began. The international collaboration plays the key role in the development of the Technical Support Organization expertise, which aim is to become the institution able to provide experts' support for decision-makers in nuclear power industry in Poland. Expertise and knowledge is expanded by the engagement in the code users international trainings, by being involved in various projects and benchmarks. The National Centre for Nuclear Research participates in, among the others, EURATOM projects such as NURESAFE (creation of BE Codes platform). Moreover NCBJ is involved in EURATOM FP7 projects such as NC2I-R (Cogeneration Initiative), ASAMPSAE (Advanced PSA), and ALLIANCE as part of the ALLEGRO project. In most of these groups our centre is taking active part in development as well as in management activities. Thanks to experiences gained and with work on research we are effectively expanding knowledge, experience and expertise to meet future's demands as a Technical Support Organization for first Nuclear

Predicting acute side effects of stimulant medication in pediatric attention deficit/hyperactivity disorder: data from quantitative electroencephalography, event-related potentials, and a continuous-performance test

Directory of Open Access Journals (Sweden)

Ogrim G

2013-09-01

Full Text Available Geir Ogrim,1–3 Knut A Hestad,3,4 Jan Ferenc Brunner,3,5,6 Juri Kropotov3,7,8 1Neuropsychiatric Unit, Østfold Hospital Trust, Fredrikstad, Norway; 2National Resource Center for ADHD, Tourettes' Syndrome and Narcolepsy, Oslo, Norway; 3Institute of Psychology, Norwegian University of Science and Technology (NTNU, Trondheim, Norway; 4Division of Mental Health, Innlandet Hospital Trust, Brumunddal, Norway; 5Department of Physical Medicine and Rehabilitation, St Olav's Hospital, Trondheim, Norway; 6Department of Neuroscience, NTNU, Trondheim, Norway; 7Institute of the Human Brain, Russian Academy of Sciences, Saint Petersburg, Russia; 8Department of Neuropsychology, Andrzej Frycz Modrzewski Krakow University, Krakow, Poland Background: The aim of this study was to search for predictors of acute side effects of stimulant medication in pediatric attention deficit/hyperactivity disorder (ADHD, emphasizing variables from quantitative electroencephalography (QEEG, event-related potentials (ERPs, and behavior data from a visual continuous-performance test (VCPT. Methods: Seventy medication-naïve ADHD patients aged 7–16 years were tested with QEEG, including a go/no-go task condition (VCPT from which behavior data and ERPs were extracted, followed by a systematic trial on stimulant medication lasting at least 4 weeks. Based on data from rating scales and interviews, two psychologists who were blind to the QEEG/ERP test results independently rated the patients as having no or small side effects (n = 37 or troublesome side effects (n = 33. We determined if the side effects were related to sex, age, IQ, ADHD subtype, comorbidities, clinical outcome, and variables in QEEG, ERPs, and VCPT. Results: There was a moderate negative correlation between clinical outcome and side effects. Three variables were significantly associated with side effects in a multivariate logistic regression analysis. In the ERP independent component – contingent negative variation

The role of international collaboration in knowledge development in creation of TSO

Energy Technology Data Exchange (ETDEWEB)

Jackowski, Tomasz Marian; Skrzypek, Elena; Spirzewski, Michal [National Centre for Nuclear Research, Otwock (Poland)

2014-12-15

National Centre for Nuclear Research has been created on September the 1{sup st} 2011 by the decree of the Polish Government with a clear goal to form Technical Support Organization for Polish regulator and public administration. It was done by merging two institutes, the former Institute of Atomic Energy POLATOM and the former Andrzej Soltan Institute for Nuclear Studies, which worldwide reputation and successful research in various fields of nuclear power-related studies are well known. The fields of activity are widely focused on the nuclear physics, cosmology, electronics as well as detectors, accelerators, material research and many more. The main factor of National Center for Nuclear Research development was the participation in the European Structural Founds program ''Swierk Computing Centre'' from the beginning. In the frame of this particular program, the collaboration with the IAEA, NEA OECD, Euratom and research and TSO organizations from different countries began. The international collaboration plays the key role in the development of the Technical Support Organization expertise, which aim is to become the institution able to provide experts' support for decision-makers in nuclear power industry in Poland. Expertise and knowledge is expanded by the engagement in the code users international trainings, by being involved in various projects and benchmarks. The National Centre for Nuclear Research participates in, among the others, EURATOM projects such as NURESAFE (creation of BE Codes platform). Moreover NCBJ is involved in EURATOM FP7 projects such as NC2I-R (Cogeneration Initiative), ASAMPSAE (Advanced PSA), and ALLIANCE as part of the ALLEGRO project. In most of these groups our centre is taking active part in development as well as in management activities. Thanks to experiences gained and with work on research we are effectively expanding knowledge, experience and expertise to meet future's demands as a Technical

Effects of immunosuppressive treatment on protein expression in rat kidney

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Kędzierska K

2014-09-01

Full Text Available Karolina Kędzierska,1 Katarzyna Sporniak-Tutak,2 Krzysztof Sindrewicz,2 Joanna Bober,3 Leszek Domański,1 Mirosław Parafiniuk,4 Elżbieta Urasińska,5 Andrzej Ciechanowicz,6 Maciej Domański,1 Tomasz Smektała,2 Marek Masiuk,5 Wiesław Skrzypczak,6 Małgorzata Ożgo,6 Joanna Kabat-Koperska,1 Kazimierz Ciechanowski1 1Department of Nephrology, Transplantology, and Internal Medicine, 2Department of Dental Surgery, 3Department of Medical Chemistry, 4Department of Forensic Medicine, 5Department of Pathomorphology, Pomeranian Medical University, 6Department of Physiology, Cytobiology, and Proteomics, West Pomeranian University of Technology, Szczecin, Poland Abstract: The structural proteins of renal tubular epithelial cells may become a target for the toxic metabolites of immunosuppressants. These metabolites can modify the properties of the proteins, thereby affecting cell function, which is a possible explanation for the mechanism of immunosuppressive agents' toxicity. In our study, we evaluated the effect of two immunosuppressive strategies on protein expression in the kidneys of Wistar rats. Fragments of the rat kidneys were homogenized after cooling in liquid nitrogen and then dissolved in lysis buffer. The protein concentration in the samples was determined using a protein assay kit, and the proteins were separated by two-dimensional electrophoresis. The obtained gels were then stained with Coomassie Brilliant Blue, and their images were analyzed to evaluate differences in protein expression. Identification of selected proteins was then performed using mass spectrometry. We found that the immunosuppressive drugs used in popular regimens induce a series of changes in protein expression in target organs. The expression of proteins involved in drug, glucose, amino acid, and lipid metabolism was pronounced. However, to a lesser extent, we also observed changes in nuclear, structural, and transport proteins' synthesis. Very slight differences

Analysis of the incidence of postintubation injuries in patients intubated in the prehospital or early hospital conditions of the hospital emergency department and the intensive care unit

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Cierniak M

2015-10-01

Full Text Available Marcin Cierniak,1 Dariusz Timler,1 Renata Sobczak,1 Andrzej Wieczorek,2 Przemyslaw Sekalski,3 Natalia Borkowska,2 Tomasz Gaszynski1 1Department of Emergency Medicine and Disaster Medicine, Barlicki University Hospital, 2Department of Anesthesiology and Intensive Therapy, Medical University of Lodz, 3Department of Microelectronics and Computer Science, IT Centre, Lodz University of Technology, Lodz, Poland Background: Intubation is still one of the best methods to secure the airway. In the case of prehospital or early hospital conditions when factors such as urgency, stress, or inaccuracy of the undertaken activities are involved, the risk of causing complications, for instance, edema or postintubation injuries, increases, especially while dealing with a difficult intubation. The risk of improper inflation of the endotracheal tube cuff also increases, which is considered in this study.Objective: The aim of this study was to evaluate the prevalence of postintubation complications, such as postintubation injuries or edema, in a research sample, and to examine whether such complications occur more often, for example, while using a guidewire. In this study, we also evaluated the injuries associated with the inflation of the endotracheal tube cuff.Materials and methods: This study was performed on a group of 153 patients intubated in prehospital conditions. The tests were carried out in three clinical sites that received patients from prehospital care. Postintubation injuries were revealed and photographed using videolaryngoscope, such as the C-MAC and the McGrath series 5. The endotracheal tube cuff pressure was measured using a pressure gage manual (VBM Medizintechnik GmbH. The quantitative analyses of differences between incidence of variables were assessed using χ2 test for P<0.05. Analyses have been carried out using the Statistica software.Results: In the group of 153 patients, postintubation injuries occurred in 17% of cases. The dependency

Estimated prevalence and incidence of diagnosed ADHD and health care utilization in adults in Sweden – a longitudinal population-based register study

Directory of Open Access Journals (Sweden)

Polyzoi M

2018-05-01

Full Text Available Maria Polyzoi,1 Ewa Ahnemark,2 Emma Medin,1,3 Ylva Ginsberg4,5 1PAREXEL International, Stockholm, Sweden; 2Medical Affairs Department, Shire Sweden AB, Stockholm, Sweden; 3Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden; 4Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 5Department of Clinical Neuroscience, Centre for Psychiatric Research, Karolinska Institutet, Stockholm, Sweden Background: Although the worldwide prevalence of attention-deficit/hyperactivity disorder (ADHD in adults is estimated to be between 2% and 5%, it is considered to be underdiagnosed. This register study explored the prevalence of diagnosed ADHD and incidence of newly diagnosed ADHD in Swedish adults over time, and assessed comorbidities and pharmacologic treatment. Methods: National Patient Register data were used to estimate the overall prevalence of adults (≥18 years with a registered ADHD diagnosis from 2006 to 2011, and the incidence of newly registered diagnoses from 2007 to 2011. Data from the Prescribed Drug Register were used to estimate the mean dose of the most frequently prescribed ADHD medication. Results: The estimated annual prevalence (N=44,364 of diagnosed ADHD increased from 0.58 per 1,000 persons in 2006 to 3.54 per 1,000 persons in 2011. The estimated annual incidence of newly diagnosed ADHD (N=24,921 increased from 0.39 per 1,000 persons to 0.90 per 1,000 persons between 2007 and 2011. At least one comorbidity was diagnosed in 52.6% of adults with ADHD (54.0% of newly diagnosed adults, with anxiety, substance use disorders, and depression being the most common. Among all adults with ADHD, 78.9% (65.7% of newly diagnosed adults were prescribed ADHD medication and one-third were prescribed more than one add-on medication. Osmotic release oral system methylphenidate was the most commonly used medication. The mean daily dose was 51.5 mg, and was

Influence of core design, production technique, and material selection on fracture behavior of yttria-stabilized tetragonal zirconia polycrystal fixed dental prostheses produced using different multilayer techniques: split-file, over-pressing, and manually built-up veneers

Directory of Open Access Journals (Sweden)

Mahmood DJH

2016-02-01

Full Text Available Deyar Jallal Hadi Mahmood, Ewa H Linderoth, Ann Wennerberg, Per Vult Von Steyern Department of Prosthetic Dentistry, Faculty of Odontology, Malmö University, Malmö, Sweden Aim: To investigate and compare the fracture strength and fracture mode in eleven groups of currently, the most commonly used multilayer three-unit all-ceramic yttria-stabilized tetragonal zirconia polycrystal (Y-TZP fixed dental prostheses (FDPs with respect to the choice of core material, veneering material area, manufacturing technique, design of connectors, and radii of curvature of FDP cores. Materials and methods: A total of 110 three-unit Y-TZP FDP cores with one intermediate pontic were made. The FDP cores in groups 1–7 were made with a split-file design, veneered with manually built-up porcelain, computer-aided design-on veneers, and over-pressed veneers. Groups 8–11 consisted of FDPs with a state-of-the-art design, veneered with manually built-up porcelain. All the FDP cores were subjected to simulated aging and finally loaded to fracture. Results: There was a significant difference (P<0.05 between the core designs, but not between the different types of Y-TZP materials. The split-file designs with VITABLOCS® (1,806±165 N and e.max® ZirPress (1,854±115 N and the state-of-the-art design with VITA VM® 9 (1,849±150 N demonstrated the highest mean fracture values. Conclusion: The shape of a split-file designed all-ceramic reconstruction calls for a different dimension protocol, compared to traditionally shaped ones, as the split-file design leads to sharp approximal indentations acting as fractural impressions, thus decreasing the overall strength. The design of a framework is a crucial factor for the load bearing capacity of an all-ceramic FDP. The state-of-the-art design is preferable since the split-file designed cores call for a cross-sectional connector area at least 42% larger, to have the same load bearing capacity as the state-of-the-art designed

Assessment of the risk of falling with the use of timed up and go test in the elderly with lower extremity osteoarthritis

Directory of Open Access Journals (Sweden)

Zasadzka E

2015-08-01

Full Text Available Ewa Zasadzka,1 Adrianna Maria Borowicz,1 Magdalena Roszak,2 Mariola Pawlaczyk1 1Department of Geriatric Medicine and Gerontology, Karol Marcinkowski University of Medical Sciences, 2Department of Computer Science and Statistics, Poznan University of Medical Sciences, Poznan, Poland Background: Falling in the elderly results in a significant number of admissions to hospitals and long-term care facilities, especially among patients with lower extremity osteoarthritis (OA.Objective: The aim of the study was to assess the risk of falling in adults older than 60 years with OA using timed up and go (TUG test.Materials and methods: A total of 187 patients (aged >60 years were enrolled in the study. The assessment included: basic activities of daily living (ADLs, lower extremity strength with the use of the 30-second chair stand test (30 CST, and assessment of the risk of falling (TUG test. Pain intensity was evaluated with the numeric rating scale (NRS.Results: The TUG test results were significantly better in younger OA patients (aged 60–69 years, as compared with their older peers (aged 70–79 years; P<0.01 and the oldest group (aged >80 years; P<0.001. Also, the 30 CST results were significantly higher in younger OA patients (P<0.05. Subjects older than 80 years had a significantly worse ADL score (P<0.05 and P<0.001. Pain complaints were reported significantly more frequently by women than men (P<0.05. A correlation between age and the TUG test score (r=0.412; P<0.0004 as well as between the TUG test and the 30 CST scores (r=0.7368; P=0.000 was detected. In the group with the TUG test score of <13.5 seconds, the 30 CST (P<0.0001 and ADL (P<0.003 results were significantly better. A comparison of fallers vs nonfallers revealed that the number of falls was significantly higher in the group of subjects who scored $13.5 when compared to <13.5 (P=0.003. Fallers significantly more often reported pain (P<0.0001, whereas nonfallers had

Clinical importance of serum HE4 and MMP2 levels in endometrial cancer patients

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Cymbaluk-Ploska A

2017-06-01

Full Text Available Aneta Cymbaluk-Płoska,1 Anita Chudecka-Głaz,1 Ewa Pius-Sadowska,2 Agnieszka Sompolska-Rzechuła,3 Bogusław Machaliński,2 Anna Surowiec,1 Janusz Menkiszak1 1Department of Gynecological Surgery and Gynecological Oncology of Adults and Adolescents, 2Department of General Pathology, Pomeranian Medical University, 3Department of Statistics, West Pomeranian University of Technology, Szczecin, Poland Introduction: Endometrial cancer is the one of the most common cancers of the genital organ. HE4 and MMP2 are both proteins whose serum levels increase in endometrial cancer.Aim: To explore the diagnostic potential of the serum levels of HE4 and MMP2 in patients with endometrial cancer and benign endometrial diseases. To assess the relationship between the serum levels of HE4 and MMP2 and the typical prognostic factors in patients with endometrial cancer.Materials and methods: Included in the study was a group of 112 patients presenting with bleeding abnormalities at the Pomeranian Medical University in years 2012–2016. Serum HE4 concentrations were measured using the Elecsys Electrochemiluminescence Immunoassay (ECLIA. MMP2 concentrations were quantified in the serum using multiplex immunoassays.Results: We observed statistically significant differences in mean serum levels of HE4 and MMP2 between the group of endometrial cancer patients and the group of patients with no changes in the endometrium (P=0.002/0.003. The diagnostic potential of HE4 and MMP2 in differentiation of high (International Federation of Gynecology and Obstetrics [FIGO] III and IV vs low (FIGO I and II clinical stage of tumor and prediction of cellular differentiation grade (G1 vs G3 on the basis of the analysis of the area under the curve is, respectively, 0.86 and 0.82 for HE4 and 0.82 and 0.74 for MMP2. The HE4 marker was significantly more specific than MMP2 in every study group and amounted to 93% vs 86% in all patients included in the analysis, 94% vs 84% in pre

Evaluation of biologically active substances promoting the development of or protecting against endometrial cancer

Directory of Open Access Journals (Sweden)

Cymbaluk-Płoska A

2018-03-01

Full Text Available Aneta Cymbaluk-Płoska,1 Anita Chudecka-Głaz,1 Anna Jagodzińska,1 Ewa Pius-Sadowska,2 Agnieszka Sompolska-Rzechuła,3 Bogusław Machaliński,2 Janusz Menkiszak1 1Department of Gynecological Surgery and Gynecological Oncology of Adults and Adolescents, Pomeranian Medical University, Szczecin, Poland; 2General Pathology Department, Pomeranian Medical University, Szczecin, Poland; 3Department of Statistics, West Pomeranian University of Technology, Szczecin, Poland Introduction: Adipose tissue is considered an endocrine organ and produces a number of biologically active substances. Aims: To consider the role that four adipokines – leptin, omentin-1, vaspin, and galectin-3 – play in the diagnosis of endometrium cancer and to investigate the association between serum concentrations of adipose tissue metabolism products and the diagnostics and prognosis in endometrial cancer. Patients and methods: The study included 168 patients with body mass index (BMI >20 kg/m2 admitted due to post-menopausal bleeding. Results: A receiver operating characteristic curves test was performed to determine the diagnostic values of the proteins tested. For leptin and galectin-3 the area under the curve (AUC values were 0.79/0.68, while for vaspin and omentin-1 the AUC values were 0.82/0.86 for all study patients. The final model identified the following independent risk factors: glucose concentration, BMI, waist circumference, leptin, and vaspin concentrations. Diagnostic values of leptin and galectin-3 with regard to differentiation between high (Fédération Internationale de Gynécologie Obstétrique [FIGO] III and IV and low (FIGO I and II stages of clinical tumor advancement and prediction of tumor grading (G1 vs G3 based on the AUC curve were 0.82/0.70 and 0.80/0.74. The AUC values for vaspin and omentin-1 with respect to differentiation between histopathological advancement and grading were 0.86/0.81 and 0.83/0.77, respectively. Significantly lower values of

Foreword

International Nuclear Information System (INIS)

Sujkowski, Z.

1998-01-01

The year 1997 was marked by the hundredth birthday anniversary of professor Andrzej Soltan, the first director of our Institute and the pioneer of nuclear physics in Poland. It is also about hundred years since nuclear physics has begun with the discovery of Polonium and Radium by Maria Sklodowska-Curie and Pierre Curie. In honour of these anniversaries an Exhibition entitled ''Nuclear Physics and Nuclear Technique in Service of Medicine - from Radium Needle to Accelerators'' has been organized. Some lectures, radio broadcasts, popular level articles have supplemented this effort to bring the present day nuclear sciences closer to the general public. In the year of 1997 227 articles in international journals have been published, supplemented by 24 invited talks and 219 communications at conferences. The lists of these publications are given separately for each of the Research Departments throughout this Annual Report. They are preceded by articles on the work in progress and by the brief overviews written by the Department Heads. The selected highlights of the past year are: progress in materials science (deep surface layers - on transformation of uranium lattice induced by water corrosion). The work on modification of surface properties by hot and cold ion implantation. In nuclear physics the careful study of polarization phenomena in the decay of light, weekly bound nuclei. The works on the properties of the heaviest elements have been continued (Adam Sobiczewski - international prizes: in 1997 the Alfred Jurzykowski and the Flerov prize). The study of new scintillation techniques provided by Marek Moszynski has also mentioned. The highlight this time is the demonstration of advantages offered by avalanche diodes for the light output readout. The particle physicists continue their involvement in various international projects. This year they managed to give a noteworthy instrumental and technical input to: Resistive Plate Chambers for the Compact Muon Solenoid

Foreword

Energy Technology Data Exchange (ETDEWEB)

Sujkowski, Z. [The Andrzej Soltan Institute for Nuclear Studies, Otwock-Swierk (Poland)

1998-12-31

The year 1997 was marked by the hundredth birthday anniversary of professor Andrzej Soltan, the first director of our Institute and the pioneer of nuclear physics in Poland. It is also about hundred years since nuclear physics has begun with the discovery of Polonium and Radium by Maria Sklodowska-Curie and Pierre Curie. In honour of these anniversaries an Exhibition entitled ``Nuclear Physics and Nuclear Technique in Service of Medicine - from Radium Needle to Accelerators`` has been organized. Some lectures, radio broadcasts, popular level articles have supplemented this effort to bring the present day nuclear sciences closer to the general public. In the year of 1997 227 articles in international journals have been published, supplemented by 24 invited talks and 219 communications at conferences. The lists of these publications are given separately for each of the Research Departments throughout this Annual Report. They are preceded by articles on the work in progress and by the brief overviews written by the Department Heads. The selected highlights of the past year are: progress in materials science (deep surface layers - on transformation of uranium lattice induced by water corrosion). The work on modification of surface properties by hot and cold ion implantation. In nuclear physics the careful study of polarization phenomena in the decay of light, weekly bound nuclei. The works on the properties of the heaviest elements have been continued (Adam Sobiczewski - international prizes: in 1997 the Alfred Jurzykowski and the Flerov prize). The study of new scintillation techniques provided by Marek Moszynski has also mentioned. The highlight this time is the demonstration of advantages offered by avalanche diodes for the light output readout. The particle physicists continue their involvement in various international projects. This year they managed to give a noteworthy instrumental and technical input to: Resistive Plate Chambers for the Compact Muon Solenoid

PLASMA-2013: International Conference on Research and Applications of Plasmas (Warsaw, Poland, 2-6 September 2013)

Science.gov (United States)

Sadowski, Marek J.

2014-05-01

, Otwock, Poland—Chairman Dimitri Batani, Universite Bordeaux, France Sergio Ciattaglia, ITER, Cadarache, France Michael Dudeck, UPMC, Paris, France Igor E Garkusha, NSC KIPT, Kharkov, Ukraine Zbigniew Kłos, CBK PAN, Warsaw Giorgio Maddaluno, ENEA Frascati, Italy Andrea Murari, EFDA JET, Culham, UK Józef Musielok, University of Opole, Poland Svetlana Ratynskaia, RIT, Stockholm, Sweden Karel Rohlena, IP CAS, Prague, Czech Republic Valentin Smirnov, Rosatom, Moscow, Russia Francisco Tabares, CIEMAT, Madrid, Spain Lorenzo Torrisi, University of Messina, Messina, Italy Jerzy Wołowski, IFPiLM, Warsaw, Poland Urszula Woźnicka, IFJ PAN, Cracow, Poland Local Organizing Committee Jerzy Wołowski—Chairman Paweł Gąsior—Secretary Zofia Kalinowska Ewa Kowalska-Strzęciwilk Monika Kubkowska Anita Pokorska Ryszard Panfil Joanna Dziak-Beme Conference website: http://plasma2013.ipplm.pl/

Cost-effective therapeutic hypothermia treatment device for hypoxic ischemic encephalopathy

Directory of Open Access Journals (Sweden)

Allen RH

2013-01-01

Full Text Available John J Kim,1,2 Nathan Buchbinder,1,† Simon Ammanuel,1,4,5,† Robert Kim,1,† Erika Moore,1 Neil O'Donnell,1 Jennifer K Lee,3 Ewa Kulikowicz,3 Soumyadipta Acharya,1 Robert H Allen,1,9 Ryan W Lee,6,7 Michael V Johnston4–81Department of Biomedical Engineering, Whiting School of Engineering, The Johns Hopkins University, 2The James Buchanan Brady Urological Institute, Department of Urology, The Johns Hopkins University School of Medicine, 3Department of Anesthesia and Critical Care Medicine, Johns Hopkins University, 4Kennedy Krieger Institute, 5Hugo W Moser Research Institute, 6Department of Neurology, 7Department of Pediatrics, 8Department of Physical Medicine and Rehabilitation Johns Hopkins University School of Medicine, Baltimore, MD; 9Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA†These authors contributed equally to this workAbstract: Despite recent advances in neonatal care and monitoring, asphyxia globally accounts for 23% of the 4 million annual deaths of newborns, and leads to hypoxic-ischemic encephalopathy (HIE. Occurring in five of 1000 live-born infants globally and even more in developing countries, HIE is a serious problem that causes death in 25%–50% of affected neonates and neurological disability to at least 25% of survivors. In order to prevent the damage caused by HIE, our invention provides an effective whole-body cooling of the neonates by utilizing evaporation and an endothermic reaction. Our device is composed of basic electronics, clay pots, sand, and urea-based instant cold pack powder. A larger clay pot, lined with nearly 5 cm of sand, contains a smaller pot, where the neonate will be placed for therapeutic treatment. When the sand is mixed with instant cold pack urea powder and wetted with water, the device can extract heat from inside to outside and maintain the inner pot at 17°C for more than 24 hours with monitoring by LED lights and thermistors

Do prescrito ao real: a gestão individual e coletiva dos trabalhadores de enfermagem frente ao risco de acidente de trabalho From prescribed to real: the collective and individual management of nursing workers toward the risk of workplace accidents

Directory of Open Access Journals (Sweden)

Davidson Passos Mendes

2012-12-01

Full Text Available Esse artigo tem por objetivo levantar os constrangimentos enfrentados pelos auxiliares e técnicos de enfermagem (AeTE de uma instituição pediátrica, vinculada a uma fundação estatal, em sua atividade de trabalho e identificar estratégias utilizadas por eles que garantam as metas de produção, a satisfação do trabalhador e a sua autoproteção contra os acidentes de trabalho. Por meio do método da AET, foram utilizados para análise e coleta de dados 34 trabalhadores de enfermagem - nível médio e técnico -, entre efetivos e contratados e, observadas as estratégias de ação e regulação destes trabalhadores frente às interfaces com que lidam. Os resultados mostram que entre os constrangimentos levantados nesta Instituição, os mais evidentes são: a dupla jornada de trabalho, a diversidade de vínculos empregatícios, os riscos a que estes profissionais estão expostos e o não conhecimento do objeto de trabalho. Verifica-se que esses constrangimentos ocasionam uma elevação das cargas de trabalho física, psíquica e cognitiva. Visando reduzir essas cargas de trabalho, o trabalhador tenta criar estratégias que são adquiridas por meio da vivência com o trabalho, das experiências e valores, para se regular frente ao risco no trabalho.The objective of this study is to analyze the constraints faced by the nursing assistants and technicians in a pediatric clinic sponsored by a state foundation during their work activities and identify the strategies adopted by them in order to guarantee the achievement of their production goals and job satisfaction and ensure their protection against workplace accidents. The method of Ergonomic Work Analysis (EWA was used for analysis and data collection of 59 tenured and temporary nursing workers with intermediate and technical level of education and to investigate the strategies related to actions and employment regulation concerning the interfaces they deal with. The results show that among

PREFACE: 10th Summer School on Theoretical Physics 'Symmetry and Structural Properties of Condensed Matter'

Science.gov (United States)

Lulek, Tadeusz; Wal, Andrzej; Lulek, Barbara

2010-03-01

also for several valuable discussion. We would like to express our thanks to all those who prepared manuscripts, to all referees who spent their time to significantly improve our elaborations, and thus the quality of this volume, to all members of our International Advisory Committee and to chairmen for their polite and efficient leading of sessions. It is our pleasure to express special gratitude to The Nicolas C Metropolis Mathematics Foundation (Los Alamos, USA) for substantial financial support of our three last SSPCM schools. Indeed, it provided an essential basis for performing these meetings. We direct this gratitude to Professor James D Louck, the President of this Foundation. Also, we were happy to hear from Professor Louck that this series of schools has had an important influence on his activities on application of unitary groups in physics. It has resulted in a new monograph: James D Louck, 'Unitary Symmetry and Combinatorics', World Scientific, New Jersey 2008, which was presented at our jubilee meeting. Tadeusz Lulek, Andrzej Wal and Barbara Lulek

Faculty of social Christian teaching at Jagiellonian University

Directory of Open Access Journals (Sweden)

Stanisław Piech

1989-12-01

Vorlesungen Andrzej Mytkowicz, ein Geistlicher und ehemaliger Universitatsprofessor fur christliche Soziologie in Lemberg, der sie bis 1938/39 fortsetzte. Zur Zeit der deutschen Besatzung, als die Krakauer Universitat bereits geschlossen war, wurde die Katcholische Soziallehre an den Priesterseminaren den Priesterseminaren fur die Diozese Krakau und Tschenstochau von Piwowarczyk unterrichtet. Nach Kriegsende ubernahm den Lehrauftrag an der JU wieder Mytkowicz und las daruber bis 1946/47. Von 1947 bis 1952 setzte diese Vortragsreihe Piwowarczyk fort, der zu dem Zeitpunkt auch Redaktionsmitglied der katholischen Wochenschrift "Tygodnik Powszechny" war. In dem Studienjahr 1952/53 wurde Piwowarczyk von Bolesław Kominek, dem spateren Kardinal und Erzbischof-Metropolit von Wrocław abgelost. Im letzten Jahr vor der Abschaffung der Theologischen Fakultat an der UJ hielt diese Vortrage Karol Wojtyła, der spatere Krakauer Erzbischof und Papst Johannes-Paul II. Obgleich in dem Zeitraum 1910-1954 die Katholische Soziallehre an der UJ nur 15 Oahre lang an einen eigens dafur eingerichteten Lehrstuhl unterrichtet werden konnte, hatte die Theologische Fakultat das Gluck, dafur jeweils die besten Wissenschaftler zu gewinnen, die - wie Zimmermann, Piwowarczyk und nicht zuletzt auch Karol Wojtyła - bis heute sehr bekannt sind.

The most important psychological and psychosocial needs of Polish multiple sclerosis patients and their significant others

Directory of Open Access Journals (Sweden)

Potemkowski A

2017-07-01

Full Text Available Andrzej Potemkowski,1 Waldemar Brola,2,3 Anna Ratajczak,4 Marcin Ratajczak,5 Mariusz Kowalewski,6 Małgorzata Lewita,6 Katarzyna Kapica-Topczewska,7 Joanna Tarasiuk,7 Adam Stępień,8 Katarzyna Gocyła-Dudar,8 Jacek Zaborski,9 Halina Bartosik-Psujek10 1Department of Clinical Psychology and Psychoprophylaxis, University of Szczecin, 2Department of Neurology, Specialist Hospital, Końskie, 3The Faculty of Medicine and Health Science, Institute of Physiotherapy, Jan Kochanowski University, Kielce, 4Pomeranian Medical University, Szczecin, 5Clinical Trial Center for MS-Patients, Szczecin, 6John Paul II Multiple Sclerosis Rehabilitation Center, Borne Sulinowo, 7Department of Neurology, Medical University of Białystok, Białystok, 8Department of Neurology, Military Institute of Medicine, Warsaw, 9Department of Neurology, Specialist Hospital in Międzylesie, Warsaw, 10Medical Faculty, University of Rzeszów, Rzeszów, Poland Background: People with multiple sclerosis (MS and their relatives often have multiple, complex needs which require support from a wide range of services. The aim of the study, the first of its kind in Poland, was to identify the most important needs of patients with MS and their significant others (SO. Methods: A questionnaire developed from focus groups consisting of 20 needs-related statements was administered in seven MS centers to 573 MS patients and 220 SO. The mean age of the patients was 42.61 years old; the mean MS duration was 9.43 years. The respondents were asked to rate the needs statements according to their importance on an 11-point scale. The questionnaire was similar for the MS patients and their SO. Results: The most important needs in the patient group were: to feel needed and efficient in life; to have easy access to professional rehabilitation; and to be sure that doctors are interested in my condition. The three most important needs in the SO group were: to know that relatives/friends feel needed and

Department of Nuclear Reactions: Overview

International Nuclear Information System (INIS)

Rusek, K.

2005-01-01

. In the series of four short contributions, recent experimental results from the HERMES Collaboration are presented. Particularly important are the results on the quark transverse spin polarisation in the nucleon. The Hermes experiments have found evidence of nonvanishing quark transverse polarisation and have provided an indication for a nonzero orbital angular momentum of quarks in the nucleon. - Atomic physics - The L-shell ionisation cross sections for atoms of some heavy elements were measured. The results are presented and compared to different model calculations. - Materials research - Our group of scientists performed many experimental studies using low-energy p-, d- and α- beams from the van de Graaff accelerator of the Department which were commissioned by other institutions. In this Annual Report the results of experiments devoted to studying damage buildup and recovery of compound semiconductors are presented. The experiments were performed at the Friedrich Schiller University of Jena, in collaboration with local scientists. Our involvement in education and science popularization has become a tradition. Students of Warsaw High Schools and of Warsaw University attended in 2004 many lectures given by Dr. Andrzej Korman and Dr. Lech Nowicki on nuclear physics, accelerators, detectors and nuclear methods in solid state physics. Our contribution to the 8 th Scientific Picnic and the 11 th Science Festival is also worth mentioning. (author)

Impact of cardiovascular risk factors on carotid intima–media thickness: sex differences

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Łoboz-Rudnicka M

2016-05-01

Full Text Available Maria Łoboz-Rudnicka,1 Joanna Jaroch,1 Zbigniew Bociąga,1 Barbara Rzyczkowska,1 Izabella Uchmanowicz,2 Jacek Polański,3 Krzysztof Dudek,4 Andrzej Szuba,5 Krystyna Łoboz-Grudzień2   1Department of Cardiology, T. Marciniak Hospital, 2Public Health Department, Wroclaw Medical University, 3Private Practice, Na Biskupinie, Wroclaw, 4Faculty of Mechanical Engineering, Wroclaw University of Technology, 5Division of Angiology, Wroclaw Medical University, Wroclaw, Poland Background and purpose: There has been growing interest in the sex-related differences in the impact of cardiovascular (CV risk factors on carotid intima–media thickness (CIMT. Therefore, we aimed at examining the influence of CV risk factors on CIMT in men and women and identifying differences between males and females in the risk profiles affecting CIMT. Patients and methods: The study group consisted of 256 patients (mean age 54.7 years, including 134 females (52%, with the following CV risk factors: arterial hypertension, type 2 diabetes mellitus, dyslipidemia, nicotine addiction, overweight, and obesity. Subjects with the history of any overt CV disease were excluded. CIMT was measured through B-mode ultrasound examination of the right common carotid artery. In the analysis of CIMT values at different ages, the patients were divided into three age groups: 1 <45 years, 2 45–60 years, and 3 >60 years. Regression analysis was used to examine the influence of CV risk factors on CIMT in men and women. Results: CIMT increased with age in both men and women. Women had lower values of CIMT than men (0.54 mm vs 0.60 mm, P=0.011. The analysis in three age subgroups revealed that CIMT values were comparable in men and women in group 1 (0.48 mm vs 0.48 mm, P=0.861, but over the age of 45 years, CIMT values became significantly lower in women compared to men (group 2: 0.51 mm vs 0.63 mm, P=0.005; group 3: 0.63 mm vs 0.72 mm, P=0.020. Significant differences were observed

Pracoholizm w kategoriach deprecjacji pracy pielęgniarki. Wybrane aspekty = Workaholism in categories of nurses’ work depreciation. Chosen aspects

Directory of Open Access Journals (Sweden)

Ewa Stychno

2016-10-01

Stychno Ewa, Kulczycka Kinga   Katedra i Zakład Zarządzania w Pielęgniarstwie, Wydział Nauk o Zdrowiu UM w Lublinie Chair and Department of Management in Nursing Faculty Health Sciences Medical University of Lublin       Słowa kluczowe: pielęgniarki, pracoholizm, stres, wypalenie zawodowe Keys words: nurses, workaholism, stress, occupational burnout syndrome       Streszczenie Pracoholizm jest zjawiskiem badanym przede wszystkim przez psychologów, którzy koncentrują się na relacjach pracoholika z bliskimi mu osobami. Ale skutki tego uzależnienia ujawniają się także w funkcjonowaniu pielęgniarki w środowisku pracy. Pielęgniarstwo należy do zawodów, w których ciągły stres jest nieodłącznym aspektem, wynikającym z natury pracy. Niewłaściwe radzenie sobie ze stresem w sytuacjach trudnych prowadzi do powstania zespołu wypalenia zawodowego. Dlatego zagadnienie to powinno stanowić obszar poszukiwań badawczych także dla kadry zarządzającej kapitałem ludzkim. Cel pracy Celem niniejszego opracowania jest omówienie pracoholizmu i jego negatywnych skutków (stres i wypalenie zawodowe w kategoriach deprecjacji pracy pielęgniarki. Pracoholizm zaburza równowagę pomiędzy pracą zawodową a życiem prywatnym. Ograniczeniu ulega zaangażowanie pracownika w życie rodzinne, brakuje czasu na realizację własnych zainteresowań. Sytuacja taka powoduje stres i zjawisko wypalenia zawodowego, a w także negatywne konsekwencje dla jednostki, jak i jej najbliższego otoczenia. Narastające trudności związane z wykonywaną pracą, stała rywalizacja, niepewność zatrudnienia będą potęgowały negatywny aspekt pracoholizmu i osłabiały mechanizmy przystosowawcze.  Wnioski Konieczne jest uświadomienie sobie przez kadrę zarządzającą faktu, iż pracownicy - pracoholicy nie przynoszą organizacji tylu korzyści, co pracownicy posiadający umiejętność panowania nad własnym życiem, pracą i rodziną.   Summary Workaholism is a

Executive Summary - Overview

International Nuclear Information System (INIS)

2005-01-01

Professor Andrzej Budzanowski was Director of IFJ in the years 1990-2004. On September 1st 2004, on IFJ joining the Polish Academy of Sciences, Professor Marek Jezabek has been nominated by the President of PAN as the Director of IFJ, for a 4-year term. Our Institute, with a personnel of 450 (182 research staff) and over 50 Ph.D. students, is presently one of the largest institutes of the Polish Academy of Sciences and one of the largest research institutes in Poland. The scientific staff consists on 120 post-doctoral researchers, 26 Associated Professors and 36 State-Nominated Professors. The total budget of the Institute for the year 2004 was about 56 million Euro. The IFJ is financed mainly from the state budget of the Ministry of Scientific Research and Information Technology. In 2004 this financing was about 4 million Euro, constituting 72% of the Institute's total budget. The remaining part of our 2004 budget came from individual research projects, also sponsored by the Ministry of Scientific Research (688 kEuro), from international projects (368 kEuro) and from the Institute's entrepreneurship activities (498 kEuro). Between 2003 and 2004 we doubled our income from international projects. For further budget information. The Scientific Council of the Institute, which consists of 40 elected members of the Institute's staff and 4 external members (elected representatives from other Polish institutes and universities), is authorized to confer Ph.D. degrees in Physics and related disciplines, and to initiate and conduct habilitation and professorship procedures. In 2003-2004 17 Ph.D. theses and 11 habilitations have been completed. Following their review procedures, 3 Associate Professors at the IFJ became state-nominated Professors, receiving their nominations from Poland's President, Mr. A. Kwasniewski. The Institute is structured into 17 scientific departments which cover the range of our scientific interests. A summary of our main scientific achievements in

WE-A-201-01: Memorial Introduction

Energy Technology Data Exchange (ETDEWEB)

Marshall, C.

2016-06-15

Regulatory Commission and may be remembered for his critique of the National Academy of Sciences BEIR III report (stating that their methodology “imposes a Delphic quality to the .. risk estimates”.) This led to his appointment as a member of the BEIR V committee. Don presented refresher courses at the AAPM, ASTRO and RSNA meetings and was active in the AAPM as a member or chair of several committees. He was the principal author of AAPM Report 43, which is essentially a critique of established clinical studies prior to 1992. He was co-editor of the Proceedings of many symposia on Time, Dose and Fractionation held in Madison, Wisconsin. He received the AAPM lifetime Achievement award in 2004. Don’s second wife of 46 years, Ann, predeceased him and he is survived by daughters Hillary and Emily, son John and two grandsons. Don was a true gentleman with a unique and erudite writing style illuminated by pithy quotations. If he had a fault it was, perhaps, that he did not realize how much smarter he was than the rest of us. This presentation draws heavily on a biography and video interview in the History and Heritage section of the AAPM website. The quote is his own. Andrzej Niemierko: Statistical modeling plays an essential role in modern medicine for quantitative evaluation of the effect of treatment. This session will feature an overview of statistical modeling techniques used for analyzing the many types of research data and an exploration of recent advances in new statistical modeling methodologies. Learning Objectives: To learn basics of statistical modeling methodology. To discuss statistical models that are frequently used in radiation oncology To discuss advanced modern statistical modeling methods and applications.

WE-A-201-02: Modern Statistical Modeling

Energy Technology Data Exchange (ETDEWEB)

Niemierko, A.

2016-06-15

Regulatory Commission and may be remembered for his critique of the National Academy of Sciences BEIR III report (stating that their methodology “imposes a Delphic quality to the .. risk estimates”.) This led to his appointment as a member of the BEIR V committee. Don presented refresher courses at the AAPM, ASTRO and RSNA meetings and was active in the AAPM as a member or chair of several committees. He was the principal author of AAPM Report 43, which is essentially a critique of established clinical studies prior to 1992. He was co-editor of the Proceedings of many symposia on Time, Dose and Fractionation held in Madison, Wisconsin. He received the AAPM lifetime Achievement award in 2004. Don’s second wife of 46 years, Ann, predeceased him and he is survived by daughters Hillary and Emily, son John and two grandsons. Don was a true gentleman with a unique and erudite writing style illuminated by pithy quotations. If he had a fault it was, perhaps, that he did not realize how much smarter he was than the rest of us. This presentation draws heavily on a biography and video interview in the History and Heritage section of the AAPM website. The quote is his own. Andrzej Niemierko: Statistical modeling plays an essential role in modern medicine for quantitative evaluation of the effect of treatment. This session will feature an overview of statistical modeling techniques used for analyzing the many types of research data and an exploration of recent advances in new statistical modeling methodologies. Learning Objectives: To learn basics of statistical modeling methodology. To discuss statistical models that are frequently used in radiation oncology To discuss advanced modern statistical modeling methods and applications.

WE-A-201-00: Anne and Donald Herbert Distinguished Lectureship On Modern Statistical Modeling

Energy Technology Data Exchange (ETDEWEB)

NONE

2016-06-15

Regulatory Commission and may be remembered for his critique of the National Academy of Sciences BEIR III report (stating that their methodology “imposes a Delphic quality to the .. risk estimates”.) This led to his appointment as a member of the BEIR V committee. Don presented refresher courses at the AAPM, ASTRO and RSNA meetings and was active in the AAPM as a member or chair of several committees. He was the principal author of AAPM Report 43, which is essentially a critique of established clinical studies prior to 1992. He was co-editor of the Proceedings of many symposia on Time, Dose and Fractionation held in Madison, Wisconsin. He received the AAPM lifetime Achievement award in 2004. Don’s second wife of 46 years, Ann, predeceased him and he is survived by daughters Hillary and Emily, son John and two grandsons. Don was a true gentleman with a unique and erudite writing style illuminated by pithy quotations. If he had a fault it was, perhaps, that he did not realize how much smarter he was than the rest of us. This presentation draws heavily on a biography and video interview in the History and Heritage section of the AAPM website. The quote is his own. Andrzej Niemierko: Statistical modeling plays an essential role in modern medicine for quantitative evaluation of the effect of treatment. This session will feature an overview of statistical modeling techniques used for analyzing the many types of research data and an exploration of recent advances in new statistical modeling methodologies. Learning Objectives: To learn basics of statistical modeling methodology. To discuss statistical models that are frequently used in radiation oncology To discuss advanced modern statistical modeling methods and applications.

Foreword. Annual report 2003

International Nuclear Information System (INIS)

Sujkowski, Z.

2004-01-01

contracts (see p. 17) gain momentum. This track is full of hurdles, expected as well as unexpected ones. Slowly, we seem to be learning how to take them. It seems to be trendy nowadays to refer to our field of research as Subatomic Physics. Obviously, this field has very strong links and/or overlaps of interests and expertise with several other branches of modern science. The prime example is of course astrophysics with its emerging subfields: the astro-nuclear and astro-particle physics. Several of us have for years been involved in some astrophysics related projects. New, high expectations raised by undertakings in this direction are described in contribution 6.15. We wish our colleagues every success in their planned expedition to Chile. Our Subatomic Physics has also strong links to and involvement in various applied sciences. It is the weakness and the strength of this field that applications are varied and scattered throughout many industries. They find their use in many other fields of research, notably in environmental studies and, last but not least, are the basis of a large number of life saving techniques. We can provide material to illustrate the relevant statement of the President of our Academy, prof. Andrzej B. Legocki: I n spite of many a common belief I claim that the driving force of any progress is fundamental research. Not only does it extend our understanding of the world around us, it also is behind all those new technologies which are essential for the advancement of civilisation'' (Forum Akademickie Nr 1, 2004, p.17). One such ''illustration'', described in contribution 5.8, concerns a new technology of producing thin superconducting films for high energy particle accelerators. Hopefully, this may become an important, economic method. This Foreword is not meant as a guide through our Report but, hopefully, should serve as an encouragement to look inside. I hope the Reader finds satisfaction in doing so. (author)

WE-A-201-01: Memorial Introduction

International Nuclear Information System (INIS)

Marshall, C.

2016-01-01

Regulatory Commission and may be remembered for his critique of the National Academy of Sciences BEIR III report (stating that their methodology “imposes a Delphic quality to the .. risk estimates”.) This led to his appointment as a member of the BEIR V committee. Don presented refresher courses at the AAPM, ASTRO and RSNA meetings and was active in the AAPM as a member or chair of several committees. He was the principal author of AAPM Report 43, which is essentially a critique of established clinical studies prior to 1992. He was co-editor of the Proceedings of many symposia on Time, Dose and Fractionation held in Madison, Wisconsin. He received the AAPM lifetime Achievement award in 2004. Don’s second wife of 46 years, Ann, predeceased him and he is survived by daughters Hillary and Emily, son John and two grandsons. Don was a true gentleman with a unique and erudite writing style illuminated by pithy quotations. If he had a fault it was, perhaps, that he did not realize how much smarter he was than the rest of us. This presentation draws heavily on a biography and video interview in the History and Heritage section of the AAPM website. The quote is his own. Andrzej Niemierko: Statistical modeling plays an essential role in modern medicine for quantitative evaluation of the effect of treatment. This session will feature an overview of statistical modeling techniques used for analyzing the many types of research data and an exploration of recent advances in new statistical modeling methodologies. Learning Objectives: To learn basics of statistical modeling methodology. To discuss statistical models that are frequently used in radiation oncology To discuss advanced modern statistical modeling methods and applications.

WE-A-201-00: Anne and Donald Herbert Distinguished Lectureship On Modern Statistical Modeling

International Nuclear Information System (INIS)

2016-01-01

Regulatory Commission and may be remembered for his critique of the National Academy of Sciences BEIR III report (stating that their methodology “imposes a Delphic quality to the .. risk estimates”.) This led to his appointment as a member of the BEIR V committee. Don presented refresher courses at the AAPM, ASTRO and RSNA meetings and was active in the AAPM as a member or chair of several committees. He was the principal author of AAPM Report 43, which is essentially a critique of established clinical studies prior to 1992. He was co-editor of the Proceedings of many symposia on Time, Dose and Fractionation held in Madison, Wisconsin. He received the AAPM lifetime Achievement award in 2004. Don’s second wife of 46 years, Ann, predeceased him and he is survived by daughters Hillary and Emily, son John and two grandsons. Don was a true gentleman with a unique and erudite writing style illuminated by pithy quotations. If he had a fault it was, perhaps, that he did not realize how much smarter he was than the rest of us. This presentation draws heavily on a biography and video interview in the History and Heritage section of the AAPM website. The quote is his own. Andrzej Niemierko: Statistical modeling plays an essential role in modern medicine for quantitative evaluation of the effect of treatment. This session will feature an overview of statistical modeling techniques used for analyzing the many types of research data and an exploration of recent advances in new statistical modeling methodologies. Learning Objectives: To learn basics of statistical modeling methodology. To discuss statistical models that are frequently used in radiation oncology To discuss advanced modern statistical modeling methods and applications.

WE-A-201-02: Modern Statistical Modeling

International Nuclear Information System (INIS)

Niemierko, A.

2016-01-01

Regulatory Commission and may be remembered for his critique of the National Academy of Sciences BEIR III report (stating that their methodology “imposes a Delphic quality to the .. risk estimates”.) This led to his appointment as a member of the BEIR V committee. Don presented refresher courses at the AAPM, ASTRO and RSNA meetings and was active in the AAPM as a member or chair of several committees. He was the principal author of AAPM Report 43, which is essentially a critique of established clinical studies prior to 1992. He was co-editor of the Proceedings of many symposia on Time, Dose and Fractionation held in Madison, Wisconsin. He received the AAPM lifetime Achievement award in 2004. Don’s second wife of 46 years, Ann, predeceased him and he is survived by daughters Hillary and Emily, son John and two grandsons. Don was a true gentleman with a unique and erudite writing style illuminated by pithy quotations. If he had a fault it was, perhaps, that he did not realize how much smarter he was than the rest of us. This presentation draws heavily on a biography and video interview in the History and Heritage section of the AAPM website. The quote is his own. Andrzej Niemierko: Statistical modeling plays an essential role in modern medicine for quantitative evaluation of the effect of treatment. This session will feature an overview of statistical modeling techniques used for analyzing the many types of research data and an exploration of recent advances in new statistical modeling methodologies. Learning Objectives: To learn basics of statistical modeling methodology. To discuss statistical models that are frequently used in radiation oncology To discuss advanced modern statistical modeling methods and applications.

Różnice deklarowanej częstości samokontroli stanu zdrowia u osób pracujących w zawodach medycznych i pozamedycznych = The difference between the declared frequency of self-health monitoring carried out by representatives of the medical and the non-medical professions

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Grzegorz Józef Nowicki

2016-05-01

3. Katedra i Zakład Pielęgniarstwa Pediatrycznego, Wydział Nauk o Zdrowiu, Uniwersytet Medyczny w Lublinie     dr n. o zdrowiu Grzegorz Józef Nowicki1, dr hab. n. med. Ewa Rudnicka-Drożak2, dr hab. n. o zdrowiu Barbara Ślusarska1, mgr Honorata Piasecka1, dr hab. n. o zdrowiu Danuta Zarzycka3, mgr Magdalena Brodowicz-Król3   1. Zakład Medycyny Rodzinnej i Pielęgniarstwa Środowiskowego, Katedra Onkologii i Środowiskowej Opieki Zdrowotnej, Wydział Nauk o Zdrowiu, Uniwersytet Medyczny w Lublinie 2. Przychodnia Lekarza Rodzinnego, CRH ŻagielMed, ul. Onyksowa 12, 20-582 Lublin 3. Katedra i Zakład Pielęgniarstwa Pediatrycznego, Wydział Nauk o Zdrowiu, Uniwersytet Medyczny w Lublinie     Słowa klucze: profilaktyka, zachowania kontroli zdrowia, osoby pracujące Key words: prevention, behavior health checks, people working   Streszczenie Wstęp: Uczestnictwo w populacyjnych badaniach profilaktycznych oraz regularne samobadanie narządów to zachowania zdrowotne zmierzające do wczesnego wykrycia chorób. Cel pracy: Określenie różnic w zakresie deklarowanej samokontroli stanu zdrowia (uczestnictwo w programach profilaktyki i samobadania narządów pomiędzy osobami wykonującymi zawód medyczny i pozamedyczny. Materiał i metody: Badania przeprowadzono wśród 598 dorosłych osób pracujących, wykonujących zawody medyczne i pozamedyczne. Narzędziem badawczym był kwestionariusz ankiety własnego autorstwa. Wyniki: Uzyskane wyniki badań wskazują, że osoby wykonujące zawód niemedyczny istotnie częściej deklarowały uczestnictwo w Ogólnopolskim Programie Profilaktyki Chorób Odtytoniowych (w tym POChP oraz w Ogólnopolskim Programie Profilaktyki Raka Jelita (p<0,001 niż badani wykonujący zawód medyczny. Natomiast kobiety, które wykonywały zawód medyczny, istotnie częściej deklarowały uczestnictwo w Ogólnopolskim Programie Profilaktyki Raka Szyjki Macicy oraz częściej wykonywały  samobadanie piersi. (p<0,001. Wnioski: Istnieje

PREFACE: Quantum dots as probes in biology

Science.gov (United States)

Cieplak, Marek

2013-05-01

photosynthetic systems. The next paper, by Olejnik et al, discussed metallic QDs which enhance photosynthetic function in light-harvesting biomolecular complexes. Such hybrid structures with gold QDs are shown to exhibit a strong increase in the fluorescence quantum yield. The next two papers, by Sikora et al and Kaminska et al deal with the ZnO nanoparticles passivated by MgO. In the first of these two papers, the authors describe the behavior of ZnO/MgO when introduced to human cancer cells. In the second, the authors describe the QDs with an extra outer layer of Fe2O3 which makes the nanoparticles superparamagnetic and also capable of generation of reactive oxygen species which could be applied to form localized centers of toxicity for cancer treatment. Finally, in the last paper by Yatsunenko et al, the authors discuss several semiconducting QDs like ZnO with various rare-earth dopands. They propose a microwave-driven hydrothermal technology to make them, characterize their luminescence and demonstrate their usefulness in the early recognition of cancer tissues. Quantum dots as probes in biology contents Quantum dots as probes in biologyMarek Cieplak Luminescent nanoparticles and their applications in the life sciencesVarun K A Sreenivasan, Andrei V Zvyagin and Ewa M Goldys Ferredoxin:NADP+ oxidoreductase in junction with CdSe/ZnS quantum dots: characteristics of an enzymatically active nanohybrid Krzysztof Szczepaniak, Remigiusz Worch and Joanna Grzyb Spectroscopic studies of plasmon coupling between photosynthetic complexes and metallic quantum dotsMaria Olejnik, Bartosz Krajnik, Dorota Kowalska, Guanhua Lin and Sebastian Mackowski Luminescence of colloidal ZnO nanoparticles synthesized in alcohols and biological application of ZnO passivated by MgOBożena Sikora, Krzysztof Fronc, Izabela Kamińska, Kamil Koper, Piotr Stępień and Danek Elbaum Novel ZnO/MgO/Fe2O3 composite optomagnetic nanoparticles I Kamińska, B Sikora, K Fronc, P Dziawa, K Sobczak, R Minikayev, W

A revision of the family Ameroseiidae (Acari, Mesostigmata), with some data on Slovak fauna

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Mašán, Peter

2017-01-01

, 1918 = Kleemannia plumosa (Oudemans, 1902); Ameroseius eumorphus Bregetova, 1977 and Kleemannia potchefstroomensis Kruger & Loots, 1980 = Kleemannia pseudoplumosa (Rack, 1972); Ameroseius gilarovi Petrova, 1986 = Kleemannia plumigera Oudemans, 1930; Ameroseius imparsetosus Westerboer, 1963 = Ameroseius georgei (Turk, 1943); Ameroseius lanatus Solomon, 1969 and Ameroseius fimetorum Karg, 1971 = Kleemannia tenella (Berlese, 1916); Ameroseius lanceosetis Livshits & Mitrofanov, 1975 = Kleemannia pavida (C. L. Koch, 1839); Ameroseius marginalis Fan & Li, 1993 and Ameroseius sichuanensis Fan & Li, 1993 = Kleemannia insignis (Bernhard, 1963); Ameroseius pseudofurcatus Livshits & Mitrofanov, 1975 = Ameroseius furcatus Karg, 1971; Ameroseius stramenis Karg, 1976 and Lasioseius (Lasioseius) gracilis Halbert, 1923 = Kleemannia delicata (Berlese, 1918); Epicriopsis langei Livshits & Mitrofanov, 1975 and Epicriopsis baloghi Kandil, 1978 = Epicriopsis palustris Karg, 1971; Epicriopsis rivus Karg, 1971 = Epicriopsis mirabilis Willmann, 1956; Neocypholaelaps ewae Haitlinger, 1987 = Neocypholaelaps indicus Evans, 1963; Neocypholaelaps lindquisti Prasad, 1968, Afrocypholaelaps ranomafanaensis Haitlinger, 1987 and Afrocypholaelaps analicullus Ho, Ma, Wang & Severinghaus, 2010 = Afrocypholaelaps africanus (Evans, 1963); Sinoseius pinnatus Huhta & Karg, 2010 = Sinoseius lobatus Bai, Gu & Fang, 1995. Ameroseius womersleyi Mašán, is a replacement name proposed for Ameroseius ornatus Womersley, 1956, a junior secondary homonym of Cornubia ornata Turk, 1943 [= Ameroseius corbiculus (Sowerby, 1806)]. Cornubia georgei Turk, 1943 is removed from synonymy with Ameroseius corbiculus (Sowerby, 1806). An annotated catalogue of the world species of Ameroseiidae is provided, partly based on type (in more than 60 species) and non-type specimens from various museum deposits and personal collections, including new or revised material from Slovakia. It contains 206 named species (138 valid species, 37

A revision of the family Ameroseiidae (Acari, Mesostigmata, with some data on Slovak fauna

Directory of Open Access Journals (Sweden)

Peter Mašán

2017-09-01

, 1918 = Kleemannia plumosa (Oudemans, 1902; Ameroseius eumorphus Bregetova, 1977 and Kleemannia potchefstroomensis Kruger & Loots, 1980 = Kleemannia pseudoplumosa (Rack, 1972; Ameroseius gilarovi Petrova, 1986 = Kleemannia plumigera Oudemans, 1930; Ameroseius imparsetosus Westerboer, 1963 = Ameroseius georgei (Turk, 1943; Ameroseius lanatus Solomon, 1969 and Ameroseius fimetorum Karg, 1971 = Kleemannia tenella (Berlese, 1916; Ameroseius lanceosetis Livshits & Mitrofanov, 1975 = Kleemannia pavida (C. L. Koch, 1839; Ameroseius marginalis Fan & Li, 1993 and Ameroseius sichuanensis Fan & Li, 1993 = Kleemannia insignis (Bernhard, 1963; Ameroseius pseudofurcatus Livshits & Mitrofanov, 1975 = Ameroseius furcatus Karg, 1971; Ameroseius stramenis Karg, 1976 and Lasioseius (Lasioseius gracilis Halbert, 1923 = Kleemannia delicata (Berlese, 1918; Epicriopsis langei Livshits & Mitrofanov, 1975 and Epicriopsis baloghi Kandil, 1978 = Epicriopsis palustris Karg, 1971; Epicriopsis rivus Karg, 1971 = Epicriopsis mirabilis Willmann, 1956; Neocypholaelaps ewae Haitlinger, 1987 = Neocypholaelaps indicus Evans, 1963; Neocypholaelaps lindquisti Prasad, 1968, Afrocypholaelaps ranomafanaensis Haitlinger, 1987 and Afrocypholaelaps analicullus Ho, Ma, Wang & Severinghaus, 2010 = Afrocypholaelaps africanus (Evans, 1963; Sinoseius pinnatus Huhta & Karg, 2010 = Sinoseius lobatus Bai, Gu & Fang, 1995. Ameroseius womersleyi Mašán, is a replacement name proposed for Ameroseius ornatus Womersley, 1956, a junior secondary homonym of Cornubia ornata Turk, 1943 [= Ameroseius corbiculus (Sowerby, 1806]. Cornubia georgei Turk, 1943 is removed from synonymy with Ameroseius corbiculus (Sowerby, 1806. An annotated catalogue of the world species of Ameroseiidae is provided, partly based on type (in more than 60 species and non-type specimens from various museum deposits and personal collections, including new or revised material from Slovakia. It contains 206 named species (138 valid species, 37 synonyms, nine

[The herbals and floristic albums of Eliza Orzeszkowa].

Science.gov (United States)

Kuźnicka, Barbara

2006-01-01

In many of her literary works, the writer and columnist Eliza Orzeszkowa (1841-1910), who was twice nominated for the Nobel Prize in literature (1905, 1909), depicted the life of the Polish society in the eastern lands of the former Polish-Lithuanian Commonwealth in the second half of the 19th century. A great lover of nature, Orzeszkowa appreciated the botanical knowledge of the local rural population in the vicinities of Grodno. She combined attempts to master that knowledge with her other great passion, that of investigating folk culture, and was always ready to listen to what women who were village herbalists had to tell her about medicinal plants, and about the customs and legends connected with the medical practices based on herbal remedies. She then passed on the information to botanists for scientific verification. Orzeszkowa's naturalist and ethnographic fascinations led her to write a cycle of articles on "The people and flowers on the Niemen river", published in 1888-1891 in the ethnographic-tourist magazine "Wisła". This collection of articles has been analysed not only by historians of literature, but also, since 1985, by historians of science. The first analysis was conducted at the Section for the History of Pharmacy of the Institute of the History of Science of the Polish Academy of Sciences. This yielded Ewa Kamińska's study: Ziołoznawstwo i ziołolecznictwo w publikacjach etnograficznych Elizy Orzeszkowej [The knowledge of herbs and medicine based on herbal remedies in the ethnographic publications of Eliza Orzeszkowa] published as part of the Institute's Historia leków naturalnych [History of natural medicines], ed. Barbara Kuźnicka, vol. I: Zródła do dziejów etnofarmacji polskiej [Sources for the history of Polish ethnopharmacy], Warszawa 1996, pp.25-88. The subject-matter of the publication aroused much interest among historians of pharmacy from Poznań. The first sign of that interest could be seen in the article by Jan Majewski and S�

Formation of ideal of legal personality

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Віта Олександрівна Сліпенчук

2016-01-01

Full Text Available Problem setting. In the process of transformation of Ukrainian society towards the assimilation and implementation of basic European values such as human rights, democracy and the rule of law the role of personality that respects the dignity of others and their right to free expression in its multifaceted manifestations becomes more important. Such definitions of it assume the character of the ideal to be pursued, but that has not received adequate expression in people's minds and in practice yet. Since this ideal inextricably links right and personality, enabling the operation of law due to the special qualities of the individual, it can be defined as the ideal of legal personality. It is the formation and realization of such ideal that becomes urgent practical task of our society, which in turn requires a comprehensive theoretical understanding. Recent research and publications analysis. It should be noted that some philosophical aspects of the meaning of legal personality and its formation are revealed in the works of Ukrainian researcher in the field of philosophy of law S.I. Maksimov. However, all actual researches are based on a certain cultural and ideological tradition. The research of  a Polish-American scholar in the history of philosophical and legal thought Andrzej Walicki pays attention to the ideological and methodological potential liberal legal philosophy of the late 19th - early 20th century in the Russian Empire, realization of which, unfortunately, failed because of the violent interruption of this tradition by Bolsheviks. Researches of philosophers of law of that period are of particular significance in this issue: Ukrainian by origin and outlook Bohdan Kistyakivskiy and one of the authors of the Universal Declaration of Human Rights (1948 Serhiy Gessen. It is reconstruction of the concept of "legal personality" in the views of philosophers of law of that period, which is really made for the first time, which will give, as

St. Patrick's Day 2015 geomagnetic storm analysis based on Real Time Ionosphere Monitoring

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García-Rigo, Alberto

2017-04-01

Alberto García-Rigo (1), David Roma-Dollase (2), Manuel Hernández-Pajares (1), Zishen Li (3), Michael Terkildsen (4), German Olivares (4), Reza Ghoddousi-Fard (5), Denise Dettmering (6), Eren Erdogan (6), Haris Haralambous (7), Yannick Béniguel (8), Jens Berdermann (9), Martin Kriegel (9), Anna Krypiak-Gregorczyk (10), Tamara Gulyaeva (11), Attila Komjathy (12), Panagiotis Vergados (12), Joachim Feltens (13,19), René Zandbergen (13), Tim Fuller-Rowell (14), David Altadill (15), Nicolas Bergeot (16), Andrzej Krankowski (17), Loukis Agrotis (18), Ivan Galkin (20), Raul Orus-Perez (21) 1. UPC-IonSAT research group, Technical University of Catalonia, Spain 2. Department of Engineering: Electronics, University of Barcelona (UB), Spain 3. Academy of Opto-Electronics, Chinese Academy of Sciences (CAS), China 4. Bureau of Meteorology, Space Weather Services, Australia 5. Canadian Geodetic Survey, Natural Resources Canada (NRCan) / Government of Canada, Canada 6. Deutsches Geodätisches Forschungsinstitut der Technischen Universität München (DGFI-TUM), Germany 7. Frederick University Cyprus, Cyprus 8. IEEA, France 9. Institute of Communications and Navigation, DLR, Germany 10. Institute of Geodesy, UWM, Poland 11. Institute of Terrestrial Magnetism, ionosphere and Radio Wave Propagation, Russian Academy of Sciences, Russia 12. NASA - Jet Propulsion Laboratory (JPL), California Institute of Technology, USA 13. Navigation Support Office, ESA-ESOC, Germany 14. NOAA affiliate, USA 15. Observatori de l'Ebre (OE), CSIC - Universitat Ramon Llull, 43520 Roquetes, Spain 16. Planetology and Reference Systems, Royal Observatory of Belgium (ROB), Belgium 17. Space Radio-Diagnostics Research Centre, UWM (SRRC/UWM), Poland 18. SYMBAN Limited, ESA-ESOC, Germany 19. Telespazio VEGA Deutschland GmbH c/o ESA-ESOC, Germany 20. University of Massachusetts Lowell, Space Science Lab, USA 21. Wave Interaction and Propagation Section (TEC-EEP), ESA-ESTEC, The Netherlands IAG's Real Time

Trudności w wykonywaniu pracy na stanowisku pielęgniarki pediatrycznej = Difficulties in performing work at the workplace of a paediatric nurse

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Kinga Dorota Kulczycka

2016-10-01

  Katedra i Zakład Zarządzania w Pielęgniarstwie Wydział Nauk o Zdrowiu Uniwersytet Medyczny w Lublinie Katedra Pielęgniarstwa Collegium Mazovia Innowacyjna Szkoła Wyższa Siedlce   Chair and Department of Management in Nursing Faculty Health Sciences Medical University of Lublin Department of Nursing Collegium Mazovia Innovative School Siedlce     dr n.med. Kinga Kulczycka, mgr Monika Grenda, dr n.med. Ewa Stychno     Słowa kluczowe: obciążenie pracą, narażenie zawodowe, pielęgniarki Key words: work load, occupational exposure, nurses Streszczenie Badaniem relacji zachodzących między pracownikiem, stanowiskiem i środowiskiem pracy zajmuje się ergonomia. Nauka ta zainteresowana jest głównie poszukiwaniem jak najlepszych rozwiązań pozwalających na optymalizację procesu pracy oraz dostosowanie ich do właściwości biologicznych człowieka. Zagrożenia zdrowia w pracy pielęgniarki pediatrycznej stanowią poważny problem, zarówno medyczny jak i społeczny. Czynniki stanowiące trudności w wykonywaniu pracy zawodowej prowadzą często do nadmiernego obciążenia. Celem pracy jest wskazanie czynników wywołujących obciążenie fizyczne u pielęgniarek pracujących na oddziałach pediatrycznych. Materiał i metody : Badania przeprowadzono w grupie 110 pielęgniarek zatrudnionych na trzech oddziałach pediatrycznych od lutego do kwietnia 2015 roku. Narzędziem badawczym był  zmodyfikowany kwestionariusz do badania obciążenia  IMDS oraz ilościowy pomiar obciążenia QWI. Opracowanie STATISTICA PL 10, i EXCELL. P<=0,05. Część badawcza. Przyjmowane niefizjologiczne pozycje oraz czynności wykonywane w skręcie, pozycji kucznej i z obciążeniem kończyn górnych stanowią podstawowe trudności. Pielęgniarki postrzegają zbyt małą przestrzeń pracy, oraz skrępowanie ciała podczas realizacji zadań nad pacjentami. Wnioski:  Planowanie zadań ich przydzielanie powinno uwzględniać odpowiednie tempo i obciążenie pracą oraz

„To nie była Ameryka”. Z Michaelem Charlesem Steinlaufem rozmawia Elżbieta Janicka (Warszawa – Nowy Jork – Warszawa, 2014–2015

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Elżbieta Janicka

2016-01-01

Full Text Available “This was not America.” Michael Charles Steinlauf in conversation with Elżbieta Janicka (Warsaw – New York – Warsaw, 2014–2015 Born in Paris in 1947, Michael Charles Steinlauf talks about his childhood in New York City, in the south of Brooklyn (Brighton Beach, in a milieu of Polish Jewish Holocaust survivors. His later experiences were largely associated with American counterculture, the New Left, an anti-war and antiracist student movement of the 1960s (Students for a Democratic Society, SDS as well as the anticapitalist underground of the 1970s (“Sunfighter”, “No Separate Peace”. In the 1980s, having undertaken Judaic Studies at Brandeis University, Steinlauf arrived in Poland, where he became part of the democratic opposition circles centred around the Jewish Flying University (Żydowski Uniwersytet Latający, ŻUL. In the independent Third Republic of Poland, he contributed to the creation of the Museum of the History of Polish Jews in Warsaw. Michael C. Steinlauf’s research interests focus on the work of Mark Arnshteyn (Andrzej Marek and of Yitskhok Leybush Peretz, Yiddish theatre as well as Polish narratives of the Holocaust. The latter were the subject of his monograph Bondage to the dead: Poland and the memory of the Holocaust (1997, Polish edition 2001 as Pamięć nieprzyswojona. Polska pamięć Zagłady. An important topic of the conversation is the dispute concerning the categories used to describe the Holocaust, including the conceptualisation of Polish majority experience of the Holocaust as a collective trauma. Controversies also arise in connection with the contemporary phenomena popularly conceptualised as the “revival of Jewish culture in Poland” and “Polish–Jewish dialogue.”  Another subject of the conversation is Michał Sztajnlauf (1940–1942, Michael C. Steinlauf’s stepbrother. The fate of the brothers was introduced into the canon of Polish culture by Hanna Krall’s short story Dybuk

General Information

International Nuclear Information System (INIS)

Wieteska, K.

2002-01-01

The Institute of Atomic Energy (IAE) emerged in 1983 as one of three research institutes formed on the basis of the Institute of Nuclear Research. Originally the main task for the IAE was research in the field of the reactor physics and techniques needed for nuclear power plant operation and maintenance. Since nineties the priorities were broadened. At present they cover the basic and applied research aiming at the development of both pro ecological energy systems and applications of new nuclear technologies in medicine and industry including nuclear and non-nuclear energy sources.The main research facility of the IAE is the MARIA reactor of 30 MW (thermal). In 2001 the reactor was used mainly for production of radioisotopes for medicine and for neutron scattering studies. The decommissioning of the old reactor EWA was finished and the final reports were prepared. In 2001 the reactor MARIA completed 36 operational cycles with operation time of 3598 hours. No abnormal situations occurred. In the frame of implementation of medium enriched fuel in MARIA reactor, at the end of 2001 only two 80% enriched fuel assembly were used in reactor core. The full conversion was expected at the beginning of 2002. The analysis of the physical parameters for operating purposes of the reactor and the exploitation of spent fuel storage facilities were performed. Based on the results from the WIW-300 installation, the flow resistance in primary fuel cooling circuit in the case of boiling was evaluated. To prevent the corrosion damage of MR spent fuel stored in technological pool of MARIA reactor, the encapsulation technology was adapted. The ecology, economy and safety of nuclear facilities were considered, taking into account the possibility of construction of a nuclear power plant in Poland. The experiments of interaction of fast neutrons from spallation source with U/Pb pile in JINR (Dubna) were performed. The Institute has also started the design and construction of a facility for

PREFACE: International Conference on the Use of X-ray (and related) Techniques in Arts and Cultural Heritage (XTACH 11)

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Hamdan, Nasser; El-Khatib, Sami

2012-07-01

The International Conference on the Use of X-Ray (and related) Techniques in Arts and Cultural Heritage (XTACH11) was held on 7 and 8 December 2011 at the American University of Sharjah (AUS) in the United Arab Emirates. The conference was organized in collaboration with the International Atomic Energy Agency (IAEA) and the National X-ray Fluorescence Laboratory (NXFL). The conference was inaugurated by Dr Peter Heath, Chancellor of the American University of Shrjah and attended by Mr Kwaku Aning, deputy Director General of the International Atomic Energy and Ambassador Hamad Al-Kaabi, Ambassador of the UAE to the International Atomic Energy university officials, faculty and students. The conference covered a variety of topics including the use of x-ray and micro beam x-ray analysis, synchrotron based techniques, ion beam and neutron based techniques, optical imaging and mass spectroscopy and chromatography techniques as well as best conservation practices. XTACH11 provided an excellent forum for scientists in the region to interact, exchange ideas and to initiate collaborations with each other as well as with the international community. It showcased some of the latest technical developments in the field of non-destructive testing for the diagnosis and conservation of cultural heritage materials. In addition to the presentations by the invited speakers (Rene van Grieken and K Janssens, University of Antwerp, Belgium; Thomas Calligaro, Centre de Recherche et de Restauration des Musees de France; Stefano Ridolfi, Ars Mensurae, Rome, Italy, and Andrzej Markowicz, IAEA, Austria), a total of 25 other research papers were also presented and discussed. Scientists from many countries participated in the conference: Austria, Belgium, Egypt, Italy, India, Iran, Iraq, Jordan, Lebanon, Qatar, Saudi Arabia, Spain, Sri Lanka, Syria, Thailand, the United Arab Emirates and Yemen. The conference concluded with a Discussion Panel. Thomas Calligaro (Centre de Recherché et de

Editorial

Directory of Open Access Journals (Sweden)

Zoran Velagić

2015-06-01

digital age explore how the emergence of subscription models influences the development of new publishing products which bring together the author and the publisher in a joint effort to reach a larger number of readers; and Ivana Hebrang Grgić (Publishing Croatian scientific journals: to e- or not to e-? discusses the extent to which Croatian journal publishers adapted to the electronic environment. In section three, dedicated to the teaching of publishing at the university level, Aušra Navickienė (Third Level Publishing Studies: Lithuania, a Case Study, Ewa Jabłońska-Stefanowicz (Three R’s in publishing education, and Josipa Selthofer (What comes first? Publishing business or publishing studies? provide examples of publishing studies programmes in Lithuania (focusing on the Institute of Book Science and Documentation of Vilnius University, Poland (focusing on the LIS Institute of the University of Wroclaw and Croatia, in comparison with relevant programmes in Europe and the United States. Finally, section four presents three papers which petition for the status of publishing studies as an emerging scientific discipline. Sophie Noël in Publishing studies: the search for an elusive academic object questions the validity of publishing studies as an academic discipline, while trying to situate them within the field of social sciences. She argues that a more appropriate frame could be adopted to describe what people studying the transformations of book publishing do – or should do – both at a theoretical and methodological levels. Christoph Bläsi (Publishing studies: being part of a cultural practice plus x? relates the question of an advanced self-conception of publishing studies to the question what criteria have to be fulfilled to call a field (such as publishing studies a scholarly discipline. He presents the first results of an ongoing project in which he conducts extensive expert interviews with representatives of UK Publishing Studies study programmes and

Mathcad in the Chemistry Curriculum Symbolic Software in the Chemistry Curriculum

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Zielinski, Theresa Julia

2000-05-01

collection of peer-reviewed documents is developing through this column at the JCE Internet Web site, http://jchemed.chem.wisc.edu/JCEWWW/Features/ McadInChem/index.html. With this column we add three peer-reviewed and tested Mathcad documents to the JCE site. In Linear Least-Squares Regression, Sidney H. Young and Andrzej Wierzbicki demonstrate various implicit and explicit methods for determining the slope and intercept of the regression line for experimental data. The document shows how to determine the standard deviation for the slope, the intercept, and the standard deviation of the overall fit. Students are next given the opportunity to examine the confidence level for the fit through the Student's t-test. Examination of the residuals of the fit leads students to explore the possibility of rejecting points in a set of data. The document concludes with a discussion of and practice with adding a quadratic term to create a polynomial fit to a set of data and how to determine if the quadratic term is statistically significant. There is full documentation of the various steps used throughout the exposition of the statistical concepts. Although the statistical methods presented in this worksheet are generally accessible to average physical chemistry students, an instructor would be needed to explain the finer points of the matrix methods used in some sections of the worksheet. The worksheet is accompanied by a set of data for students to use to practice the techniques presented. It would be worthwhile for students to spend one or two laboratory periods learning to use the concepts presented and then to apply them to experimental data they have collected for themselves. Any linear or linearizable data set would be appropriate for use with this Mathcad worksheet. Alternatively, instructors may select sections of the document suited to the skill level of their students and the laboratory tasks at hand. In a second Mathcad document, Non-Linear Least-Squares Regression, Young and

BOOK REVIEW Cracking the Einstein Code: Relativity and the Birth of Black Hole Physics With an Afterword by Roy Kerr Cracking the Einstein Code: Relativity and the Birth of Black Hole Physics With an Afterword by Roy Kerr

Science.gov (United States)

Carr, Bernard

2011-02-01

, where he wrote his seminal paper. The second strength of this book is that it shows how Kerr's discovery related to other developments in the field. Progress in physics is rarely made in isolation and there is a strong supporting cast in this drama. The key to his breakthrough was the simplification of Einstein's equations entailed in studying what are termed `shear-free' solutions. The first clue came from Ray Sachs, whose studies of asymptotically shear-free bundles of light-rays reduced Einstein's equations to manageable form. Ivor Robinson and Andrzej Trautman then considered bundles which are shear-free everywhere but they were looking for solutions with gravity waves rather than time-independent ones and so missed the great discovery. Kerr learnt about these developments at a 1962 meeting on Gravitation and General Relativity in Warsaw, which clearly played a seminal role in the development of his ideas. But what most excited him was the enthusiastic summary of Vitaly Ginzburg, extolling the virtues of general relativity and emphasizing the need to understand strong gravity effects such as rotation. In any case, he returned to Austin convinced that he had the tools required to solve the problem. At first, he was discouraged when Newman claimed to prove that no shear-free space is possible but fortunately Kerr found a mistake in this work. By using coordinates which incorporated the rotational symmetry of the problem, he was able to find an exact solution in which the metric contains an event horizon and is asymptotically rotating. Since the Warsaw meeting played such a crucial role, it is interesting to recall that Richard Feynman also attended the meeting and described it in rather unflattering terms in a letter to his wife [2]: `I am not getting anything out of the meeting. I am learning nothing. Because there are no experiments, this field is not an active one, so few of the best men are doing work in it. The result is that there are hosts of dopes here and it

6th International Symposium on Molecular Allergology (ISMA

Directory of Open Access Journals (Sweden)

Christiane Hilger

2016-10-01

Mills, Adrian Rogers, Aage Otherhals P65 Fish and peanut allergens interact with plasma membranes of intestinal and bronchial epithelial cells and induce differential gene expression of cytokines and chemokines Tanja Kalic, Isabella Ellinger, Chiara Palladino, Barbara Gepp, Eva Waltl, Verena Niederberger-Leppin, Heimo Breiteneder P66 Interleukin 4 affects fat tissue metabolism and expression of pro-inflammatory factors in isolated rat adipocytes Dawid Szczepankiewicz, Ewa Pruszynska-Oszmalek, Marek Skrzypski, Krzysztof W. Nowak, Aleksandra Szczepankiewicz P67 Ozone induced airway hyperreactivity in PD-L2−/− mice model Gwang-Cheon Jang P68 Thymic stromal lymphopoietin (TSLP and its receptor as targets for the development of anti-inflammatory inhibitory agents Iva Markovic, Andreas Borowski, Tina Vetter, Andreas Wohlmann, Michael Kuepper, Karlheinz Friedrich P69 The mononuclear phagocyte system in experimentally-induced allergic rhinitis Ibon Eguiluz Gracia, Anthony Bosco, Ralph Dollner, Guro Reinholt Melum, Anya C Jones, Maria Lexberg, Patrick G Holt, Espen Sønderaal Bækkevold, Frode Lars Jahnsen P70 Expression of histamine metabolizing enzymes is increased in allergic children Aleksandra Szczepankiewicz, Paulina Sobkowiak, Marta Rachel, Beata Narozna, Dorota Jenerowicz, Witold Swiatowy, Anna Breborowicz P71 Modifying the glycosylation of human IgE towards oligomannosidic structures does not affect its biological activity Melanie Plum, Sara Wolf, Frank Bantleon, Henning Seismann, Frederic Jabs, Michaela Miehe, Thilo Jakob, Edzard Spillner P72 Flying Labs: an educational initiative to transfer allergy research into high-school settings Michael Wallner, Heidi Hofer, Fatima Ferreira, Reinhard Nestelbacher P73 Clinical significance of antihistamines and Kujin, an anti-allergic Kampo medicine Hiroyuki Fukui