Lee, Mun Ho; Kim, Dong Jip; Lee, Jang Kyu; Seo, Byong Sul; Lee, Soon Hyung
In view of its prevalence in the Far East area, a more detailed knowledge on the hookworm infection is one of the very important medical problem. The present study was aimed to determine the infectivity of the artificially hatched ancylosotma duodenale larvae in man after its oral administration, evaluate the clinical symptomatology of such infection, determine the date of first appearance of ova in the stool, calculate the blood loss per worm per day, assess the relation-ships between the ova count, infectivity (worm load), blood loss and severity of anemia. An erythrokinetic study was also done to analyse the characteristics of hookworm anemia by means of 59 Fe and 51 Cr.
Millán, J.; Blasco-Costa, Maria Isabel
Roč. 186, 3-4 (2012), s. 518-522 ISSN 0304-4017 Institutional support: RVO:60077344 Keywords : Ancylostomiasis * Hookworm * Reservoir * Spain Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 2.381, year: 2012 http://www.sciencedirect.com/science/article/pii/S030440171100759X#
Kasus diare pada anjing di Klinik Hewan Makassar banyak dilaporkan. Helmintiasis merupakan salah satu diagnosis yang cukup sering dialporkan dalam pemeriksaan disamping diagnosis lainnya seperti : perubahan diet, food intolerance, infeksi bakteri dan virus. Kasus helmintiasis pada anjing yang sampai saat ini banyak dilaporkan diantaranya adalah ancylostomiasis dan toxocariasis. Selain itu, beberapa kasus lain yang kurang namun tetap dilapo...
Hookworms belonging to the genus Ancylostoma cause ancylostomiasis, a disease of considerable concern in humans and domestic and wild animals. Molecular and epidemiological data support evidence for the zoonotic potential among species of Ancylostoma where transmission to humans is facilitated by ra...
Full Text Available The Instituto Venezolano de Investigaciones Cientificas (IVIC is a government-funded multidisciplinary academic institution dedicated to research, development and technology in many areas of knowledge. Biomedical projects and publications comprise about 40% of the total at IVIC. In this article, we present an overview of some selected research and development projects conducted at IVIC which we believe contain new and important aspects related to malaria, ancylostomiasis, dengue fever, leishmaniasis and tuberculosis. Other projects considered of interest in the general area of tropical medicine are briefly described. This article was prepared as a small contribution to honor and commemorate the centenary of the Instituto Oswaldo Cruz.
Importância da reabsorção do ferro da hemorragia intestinal provocada pela ação dos vermes na progressão da anemia The importance of iron reabsorption in intestinal hemorrhage caused by worms in the course of anemia
Full Text Available Foram estudados 10 doentes, portadores de anemia ancilostomótica e de grande parasitose. Foram determinados alguns parâmetros hematológicos como dosagem de hemoglobina, contagem de hemácias, hematócrito, volume corpuscular médio, hemoglobina corpuscular média, ferro sérico e siderofilina. Foram estudados o volume da perda de sangue intestinal, o ferro perdido nesta hemorragia e eliminado nas fezes, e o ferro reaborvido da hemorragia intestinal. Conclui-se que a reabsorção do ferro da hemoglobina por dia no tubo digestivo é de suma importância no retardamento da instalação da anemia ferropriva, causada pela parasitose ancilostomótica.Ten patients presenting ancylostomotic anemia and a high rate of parasitosis were submitted to several hematologic determinations: hemoglobin level, erythrocyte count, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, serum iron level, and transferrin. In addition, measurements were made of the blood volume lost by intestinal bleeding, of iron loss through hemorrhage and in feus, and of iron reabsorption from intestinal bleeding. The main reason for the late appearance of iron deficiency anemia in ancylostomiasis is the high degree of dally iron absorption in the digestive tract, originating from hemoglobin breakdown.
Zhang, Lili; Shen, Junsong; Guo, Linchun; Cheng, Fenggan; Fan, Qi; Ni, Keqian; Xia, Shujing; Zhou, Detong
The present study aimed to determine the diagnostic yield of OMOM capsule endoscopy for small bowel diseases in adults. A total of 89 patients, including 45 cases of obscure abdominal pain, 22 of chronic diarrhea, 18 of obscure gastrointestinal bleeding and 4 of obscure anemia were enrolled in the present study. The transit time of the endoscopy capsule in the digestive tract was recorded and the testing results were analyzed. All detections were completed except for four capsule retentions and the completion rate was 95.51%. The average transit time of the endoscopy capsule in the esophagus, stomach and small intestine was 62.18±64.23 sec, 67.46±63.13 and 346.53±102.81 min, respectively. Of the 89 patients, 54 (60.67%) were found to have lesions, among which 19 had mucosal erosion (21.35%), 15 had anabrosis (16.85%), 9 were diagnosed with polyps (10.11%), 5 with angiodysplasia (5.62%); furthermore, tumors were identified in 5 patients (5.62%) and ancylostomiasis in 1 patient (1.12%). The results confirmed the feasibility and validity of OMOM capsule endoscopy for diagnosing small bowel diseases in adults.
Roberto Coello Peralta
Full Text Available En la investigación se determinó la incidencia de Ancylostoma caninum en perros domésticos de la comuna “Limoncito” de la parroquia Chongón, provincia del Guayas, entre los meses de diciembre del 2014 a marzo del 2015. Para la identificación de este geohelminto, se utilizaron los métodos de flotación en solución sobresaturada de azúcar sin centrifugación y se confirmaron los casos con Baermann modificado, Se aplicó para este estudio un diseño experimental no paramétrico–prospectivo–transversal. Los caninos evaluados, de raza mestiza, tenían edades entre los 3 meses a 10 años, 74 fueron machos y 50 hembras, todos los perros estaban en domicilios y por tanto tenían propietarios. De un total de 124 muestras (uno/animal, 14 resultaron positivas para A. caninum, de las cuales cinco pertenecían a animales que presentaron sintomatología con Ancylostomiasis como: tos, debilidad, deshidratación, mucosas pálidas, diarrea acuosa y con presencia de sangre o mocos, de aquellos sintomáticos uno murió; esto permitió determinar la incidencia, con un resultado del 11,29%. Se concluye que es evidente la presencia de este parásito en el sitio de estudio, lo que constituye un problema de salud animal y que podría convertirse en un serio problema de salud pública, por el riesgo de transmitirse a los habitantes del sector.
Cediel, Natalia; Villamil, Luis Carlos; Romero, Jaime; Renteria, Libardo; De Meneghi, Daniele
To establish priorities for zoonoses surveillance, prevention, and control in Bogotá, Colombia. A Delphi panel of experts in veterinary and human medicine was conducted using a validated prioritization method to assess the importance of 32 selected zoonoses. This exercise was complemented by a questionnaire survey, using the knowledge, attitudes, and practices (KAP) methodology, administered in 19 districts of Bogotá from September 2009 to April 2010 to an at-risk population (workers at veterinary clinics; pet shops; butcher shops; and traditional food markets that sell poultry, meat, cheese, and eggs). A risk indicator based on level of knowledge about zoonoses was constructed using categorical principal component and logistic regression analyses. Twelve experts participated in the Delphi panel. The diseases scored as highest priority were: influenza A(H1N1), salmonellosis, Escherichia coli infection, leptospirosis, and rabies. The diseases scored as lowest priority were: ancylostomiasis, scabies, ringworm, and trichinellosis. A total of 535 questionnaires were collected and analyzed. Respondents claimed to have had scabies (21%), fungi (8%), brucellosis (8%), and pulicosis (8%). Workers with the most limited knowledge on zoonoses and therefore the highest health risk were those who 1) did not have a professional education, 2) had limited or no zoonoses prevention training, and 3) worked in Usme, Bosa, or Ciudad Bolívar districts. According to the experts, influenza A(H1N1) was the most important zoonoses. Rabies, leptospirosis, brucellosis, and toxoplasmosis were identified as priority diseases by both the experts and the exposed workers. This is the first prioritization exercise focused on zoonoses surveillance, prevention, and control in Colombia. These results could be used to guide decision-making for resource allocation in public health.
Relação entre os níveis de vitamina A e os marcadores bioquímicos do estado nutricional de ferro em crianças e adolescentes Relationship between vitamin A and biochemical markers of iron status in children and adolescents
Rita de Cássia Ribeiro Silva
positive and statistically significant association was found between the levels of serum retinol and hemoglobin (p=0.007, serum iron (p=0.010 and iron-saturated tranferrin (p=0.027. These findings remained unchanged after adjusting the models for demographic variables, parasitic infections (Schistosoma mansoni, Trichiura trichuris, Ascaris lumbricoides and ancylostomiasis, consumption of bioavailable dietary iron and environmental and home conditions. CONCLUSION: Vitamin A seems to contribute to the increase of organic iron of the population, especially in areas were deficiency of vitamin A and iron-deficiency anemia coexist.
Rita de Cássia Ribeiro Silva
Full Text Available OBJECTIVE: This study aims to assess the association between geohelminth infections and the physical growth of schoolchildren. METHODS: This is a cross-sectional study with the participation of 1861 children aging from 7 to 14 years who live in a municipality in the Southern region (Recôncavo of the State of Bahia. The participants were submitted to anthropometric assessment and stool tests. Multiple logistic regression analysis was used as the statistical means to determine the association of interest. RESULTS: The risks of stunting were greater among boys with Ascaris lumbricoides (Odds ratio=1.79; confidence interval 95%: 1.07-3.01, Trichuris trichiura (Odds ratio=2.26; confidence interval 95%: 1.33-3.84 and ancylostomiasis (Odds ratio=2.18; confidence interval 95%: 1.28-3.73 when compared with non-infected children. These results remained unchanged after adjustments for the location of the school, children's ages and other geohelminth infections. CONCLUSION: These infections did not compromise girls´ growth. These results emphasize the association between geohelminth infection and linear physical growth, indicating the need to implement preventive and curative measures that allow the quality of life of the children to improve since the repercussion that these parasites have on the nutritional status and health of this population is severe.OBJETIVO: Este estudo visa a avaliar a associação entre infecções geohelminticas e o crescimento físico de escolares. MÉTODOS: Trata-se de um estudo de corte transversal em que participaram 1851 indivíduos com idades entre 7 e 14 anos, residentes em um município do Recôncavo Sul do Estado da Bahia. Os indivíduos foram submetidos a avaliação antropométrica e a exame parasitológico de fezes. Utilizou-se a análise de regressão logística múltipla como técnica estatística para avaliar a associação de interesse. RESULTADOS: Os riscos de déficit do crescimento linear foram mais
Xie, Yue; Hoberg, Eric P; Yang, Zijiang; Urban, Joseph F; Yang, Guangyou
Hookworms belonging to the genus Ancylostoma (Dubini, 1843) cause ancylostomiasis, a disease of considerable concern in humans and domestic and wild animals. Molecular and epidemiological data support evidence for the zoonotic potential among species of Ancylostoma where transmission to humans is facilitated by rapid urbanization and increased human-wildlife interactions. It is important to assess and describe these potential zoonotic parasite species in wildlife, especially in hosts that have physiological similarities to humans and share their habitat. Moreover, defining species diversity within parasite groups that can circulate among free-ranging host species and humans also provides a pathway to understanding the distribution of infection and disease. In this study, we describe a previously unrecognized species of hookworm in the genus Ancylostoma in the giant panda, including criteria for morphological and molecular characterization. The hookworm specimens were obtained from a wild giant panda that died in the Fengtongzai Natural Reserve in Sichuan Province of China in November 2013. They were microscopically examined and then genetically analyzed by sequencing the nuclear internal transcribed spacer (ITS, ITS1-5.8S-ITS2) and mitochondrial cytochrome c oxidase subunit 1 (cox1) genes in two representative specimens (one female and one male, FTZ1 and FTZ2, respectively). Ancylostoma ailuropodae n. sp. is proposed for these hookworms. Morphologically the hookworm specimens differ from other congeneric species primarily based on the structure of the buccal capsule in males and females, characterized by 2 pairs of ventrolateral and 2 pairs of dorsolateral teeth; males differ in the structure and shape of the copulatory bursa, where the dorsal ray possesses 2 digitations. Pairwise nuclear and mitochondrial DNA comparisons, genetic distance analysis, and phylogenetic data strongly indicate that A. ailuropodae from giant pandas is a separate species which shared a
Setting priorities for surveillance, prevention, and control of zoonoses in Bogotá, Colombia Establecimiento de prioridades en la vigilancia, la prevención y el control de las zoonosis en Bogotá, Colombia
Full Text Available OBJECTIVE: To establish priorities for zoonoses surveillance, prevention, and control in Bogotá, Colombia. METHODS: A Delphi panel of experts in veterinary and human medicine was conducted using a validated prioritization method to assess the importance of 32 selected zoonoses. This exercise was complemented by a questionnaire survey, using the knowledge, attitudes, and practices (KAP methodology, administered in 19 districts of Bogotá from September 2009 to April 2010 to an at-risk population (workers at veterinary clinics; pet shops; butcher shops; and traditional food markets that sell poultry, meat, cheese, and eggs. A risk indicator based on level of knowledge about zoonoses was constructed using categorical principal component and logistic regression analyses. RESULTS: Twelve experts participated in the Delphi panel. The diseases scored as highest priority were: influenza A(H1N1, salmonellosis, Escherichia coli infection, leptospirosis, and rabies. The diseases scored as lowest priority were: ancylostomiasis, scabies, ringworm, and trichinellosis. A total of 535 questionnaires were collected and analyzed. Respondents claimed to have had scabies (21%, fungi (8%, brucellosis (8%, and pulicosis (8%. Workers with the most limited knowledge on zoonoses and therefore the highest health risk were those who 1 did not have a professional education, 2 had limited or no zoonoses prevention training, and 3 worked in Usme, Bosa, or Ciudad Bolívar districts. CONCLUSIONS: According to the experts, influenza A(H1N1 was the most important zoonoses. Rabies, leptospirosis, brucellosis, and toxoplasmosis were identified as priority diseases by both the experts and the exposed workers. This is the first prioritization exercise focused on zoonoses surveillance, prevention, and control in Colombia. These results could be used to guide decision-making for resource allocation in public health.OBJETIVO: Establecer prioridades en la vigilancia, la prevención y
Enio Garcia Goulart
êmicas. Pelas suas características, tais como aceitação popular, pequeno custo operacional e, sobretudo, obtenção de resultados a curto prazo, será altamente oportuno, considerando-se que os recursos convencionais são baseados na educação e engenharia sanitárias, cujos resultados são obtidos a médio e longo prazos e sempre dependentes de cada indivíduo. Além da aplicação médico-sanitária, a presente pesquisa poderá estabelecer possibilidades na profilaxia de certas fitonoses e zoonoses de grande importância econômica na agropecuária.The previously reported activity of natural products of plant origin which inhibit the external larval evolution of Ancylostomidae and of Strongyloides stercoralis, has now been applied in the pratical ecological prophylaxis of human parasitic disease. The study was made in two populations of low economic level inhabiting shanty towns on the Ilha do Governador, Rio de Janeiro, Brasil. During 26 months the following phases were completed: 1 - selection and census ofeach area; 2 - parasitological survey; 3 - mass treatment of both populations with the anthelminthics pyrantel pamoate and thiabendazole, this treatment repeated 10 months later; 4 - introduction of plants with parasitic inhibitory activity in one area, leaving the other as control; 5 - three epidemiological Controls, one after each treatment and then at intervals of 60 to 70 days to determine the prevalence and reinfection leveis of the two parasites in each area. Of the plants introduced only lemon-grass, Cymbopogon citratus, survived and attained an average density of one dump per 10 m². Ancylostomiasis levels fell in the plantedarea from 23.2% to 2.2% and in the control are from 14.5% to 5.8% during the twenty-one month study. Strongyloidiasis fell from 17.1% to 0.6% in the planted area, and from 13% to 2.9% in the control area. 46% of the initially examined populations were followed through to the end. The reduction in prevalence of hookworms, 30.5% higher in
Teatro na educação de crianças e adolescentes participantes de ensaio clínico Teatro en la educación de niños y adolescentes participantes de ensayo clínico Theater in the education of children and teenagers participating in a clinical trial
Maria Flávia Gazzinelli
envueltos en la prueba de una vacuna contra anquilostomiasis. La muestra por conveniencia estaba constituida por 13 estudiantes de diez a 17 años, de ambos sexos, de la Escuela Municipal de Maranhao, MG, Brasil, 2009. Se utilizó un cuestionario estructurado aplicado pre y post intervención. El dispositivo pedagógico fue el Teatro del Oprimido. Las variables dependientes fueron el conocimiento específico y global sobre la investigación clínica y sobre helmintiasis; la variable independiente fue la participación en la intervención educativa. RESULTADOS: Hubo aumento del conocimiento sobre señales y síntomas, susceptibilidad a la reinfección y modo de contagio de la helmintiasis posterior a la intervención educativa. Aumentaron los aciertos relativos a la duración de la investigación clínica, a los procedimientos previstos, a la posibilidad de desistencia de la participación y de ocurrencia de eventos adversos. Permaneció la noción de que el propósito primario de la investigación es terapéutico, a pesar de que hubo reducción en el porcentaje de participantes que asociaron la investigación al tratamiento médico. El Teatro del Oprimido posibilitó que las discusiones sobre helmintiasis y de la investigación clínica fueran contextualizadas y materializadas. Los individuos pudieron despojarse o reducir sus representaciones previas. CONCLUSIONES: La participación de niños y adolescentes en ensayos clínicos debe ser precedida por intervención educativa, ya que individuos de ese grupo etario no pudieron siquiera reconocer que tienen derecho a decidir por sí mismos.OBJECTIVE: To analyze the effects of a pedagogical intervention on the learning of children and teenagers participating in a clinical research. METHODS: Quantitative, quasi-experimental and longitudinal study, part of a group of studies conducted to test a vaccine against ancylostomiasis. Convenience sample with 133 students aged 10-17 years, of both sexes, from the school Escola Municipal de