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  1. Le français du tourisme dans le contexte universitaire chinois : analyse comparative des besoins

    Directory of Open Access Journals (Sweden)

    LI Lu

    2016-11-01

    Full Text Available Cette recherche vise à dévoiler la situation de l’enseignement du français du tourisme dans le contexte universitaire chinois. A travers une analyse des besoins, nous tâchons de vérifier si la formation actuelle correspond aux besoins des apprenants ainsi qu’à la demande du marché du travail. Des enquêtes ont été menées auprès d’étudiants, d’enseignants et de professionnels. Les résultats montrent que les publics se diversifient avec des besoins variés et que la rupture de l’ensei gnement avec le secteur professionnel est évidente. Trois propositions sont ainsi formulées en vue de fournir des conseils à l’amélioration et à l’innovation de la formation du français du tourisme dans les universités chinoises.

  2. Fédéralisme et droits des LGBT aux États-Unis et au Canada : analyse comparatives des politiques

    Directory of Open Access Journals (Sweden)

    Miriam Smith

    2014-12-01

    Full Text Available L’article examine le militantisme LGBT et les résultats des politiques en matière de droit pénal et du mariage entre personnes de même sexe de 1969 à aujourd’hui, dans le cadre d’une analyse comparée du fédéralisme aux États-Unis et au Canada. Nous soutiendrons que le fédéralisme a grandement façonné les politiques publiques relatives aux droits des LGBT. Dans le régime américain, le potentiel d’expansion du fédéralisme a favorisé les changements graduels de politiques dans les États et, parallèlement, les multiples points de véto créés par le système de séparation des pouvoirs conjugués aux compétences conférés aux États dans d’importants domaines de politiques ont entravé ces changements de politiques. Dans le régime canadien, la centralisation des mécanismes de protection des droits de la personne dans la Charte de même que la dynamique descendante de l’exercice du pouvoir dans le régime parlementaire de type Westminster ont facilité les changements de politiques. Le fédéralisme est souvent perçu comme un obstacle à l’adoption de politiques progressistes. La répartition des pouvoirs entrave l’élaboration de politiques cohérentes et prête le flanc à la prolifération de vétos dont peuvent se prévaloir des groupes influents pour freiner le changement. Les critiques de cette perspective arguent depuis longtemps que, même si le fédéralisme multiplie les points de véto, il présente aussi de nombreuses possibilités d’innovation. Ils font valoir que les groupes ont plus de poids dans les régimes fédéraux puisqu’ils peuvent exercer leur influence à deux paliers de gouvernement plutôt qu’à un. Ainsi, un groupe qui ne réussit pas à se faire entendre à l’un des paliers pourra tenter sa chance au second et pourra même dresser un palier contre l’autre pour atteindre ses objectifs stratégiques.

  3. Analyse comparative entre la distribution des fréquences de ...

    African Journals Online (AJOL)

    2016 International Formulae Group. All rights reserved. Mots clés: Hydrogéochimie, conductivité électrique, diagramme de Piper, socle cristallin et cristallophyllien, Côte d'Ivoire. English Title: Comparative analysis of electrical conductivity frequencies distribution and geochemical facies of hard rock aquifers waters (Ivory ...

  4. ANALYSE DES PERCEPTIONS LOCALES ET DES FACTEURS ...

    African Journals Online (AJOL)

    AISA

    1Faculté des Sciences Agronomiques (FSA), Université d'Abomey-Calavi (UAC), 01 BP 526 Cotonou Bénin. Email : cgbemavo@yahoo.fr. 2Institut National des Recherches Agricoles du Bénin, Centre de Recherches Agricoles d'Agonkanmey (CRA-A),. Laboratoire des Sciences du Sol, Eau et Environnement (LSSEE).

  5. Citations des ressources électroniques dans les publications scientifiques : analyse comparée et stratégie des liens

    OpenAIRE

    Chartron , Ghislaine; Caillon , Elisabeth

    2008-01-01

    International audience; Cette communication s'intéresse aux nouvelles dimensions de la citation dans les textes scientifiques dans le contexte numérique. A l'appui d'une étude exploratoire quantitative menée fin 2007 et début 2008 dans le domaine de la biologie moléculaire, de la physique appliquée et de l'économie-gestion, les résultats montrent une faible intégration de ressources Web dans les textes (en dehors des versions en ligne des vecteurs traditionnels), sauf pour la biologie molécul...

  6. L`ANALYSE COMPARATIVE DES FUSIONS-ACQUISITIONS AVEC LES AUTRES FORMES DE CROISSANCE DES ENTREPRISES (II- FUSIONS- ACQUISITIONS VS. ALLIANCES

    Directory of Open Access Journals (Sweden)

    Vancea Mariana

    2010-12-01

    Full Text Available Development through mergers and acquisitions is a companys external growth strategy, as well as business alliances, but these options can not be mistaken, because the characteristics, stakes and risks are fundamentally different nature. In this paper we intent to analyze mergers and acquisitions compared with other ways of the companys external growth, by presenting the main similarities and differences between them.

  7. Contesting Citizenship: Comparative Analyses

    DEFF Research Database (Denmark)

    Siim, Birte; Squires, Judith

    2007-01-01

    importance of particularized experiences and multiple ineequality agendas). These developments shape the way citizenship is both practiced and analysed. Mapping neat citizenship modles onto distinct nation-states and evaluating these in relation to formal equality is no longer an adequate approach....... Comparative citizenship analyses need to be considered in relation to multipleinequalities and their intersections and to multiple governance and trans-national organisinf. This, in turn, suggests that comparative citizenship analysis needs to consider new spaces in which struggles for equal citizenship occur...

  8. Analyse des caractéristiques structurelles et des performances ...

    African Journals Online (AJOL)

    SARAH

    28 févr. 2014 ... performances technico-économiques de la riziculture irriguée en Côte d' .... en nous basant sur les prix des intrants et des produits en vigueur au cours ..... la recherche et de la vulgarisation et le transfert de technologies ; (2) ...

  9. Dictionnaire d'analyse et de gestion des risques

    CERN Document Server

    Desroches, Alain

    2005-01-01

    Ce dictionnaire présente les principaux termes utilisés en analyse et gestion des risques, pour tous les secteurs d'activité industrielle ou de service. Il permet de clarifier des terminologies existantes présentant des variations plus ou moins importantes et parfois des contradictions de sens. Il propose : premièrement, la définition des auteurs, définition correspondant à l'usage le plus courant du terme , deuxièmement, les différences avec les terminologies existantes (essentiellement des normes) , troisièmement, des compléments à la définition, lorsque cela semble nécessaire et notamment lorsqu'il est important de préciser le contexte d'utilisation du terme , en dernier lieu, des exemples pratiques d'application, lorsque cela peut apporter un éclairage complémentaire pertinent.

  10. Des stratégies de changement dans les organisations internationales : une analyse comparée du HCR et de l’OIT

    OpenAIRE

    Louis, Marieke; Maertens, Lucile

    2014-01-01

    Partant d’une comparaison inédite entre le Haut Commissariat des Nations Unies pour les réfugiés (HCR) et l’Organisation internationale du travail (OIT), cet article suggère de revisiter la problématique du changement dans les organisations internationales en montrant, dans une perspective de sociologie des relations internationales, l’existence d’un continuum de stratégies organisationnelles mises en place par ces dernières pour légitimer leur existence et leur action, stratégies allant de l...

  11. Regroupement des statistiques sur le secteur des TIC et analyse ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    La présence et l'influence des technologies de l'information et de la communication (TIC) continuent de s'élargir et de s'accroître, tout comme leurs répercussions sur le développement économique. Toutefois, il reste encore beaucoup de travail à faire avant de pouvoir comprendre d'une manière systématique et ...

  12. Analyse und Verbesserung der Simulationsmethode des Bremsenquietschens

    OpenAIRE

    Gräbner, Nils

    2016-01-01

    Bremsenquietschen ist ein Phänomen, bei dem das gesamte Bremssystem innerhalb des hörbaren Frequenzbereichs von 1 kHz – 16 kHz schwingt. Aus Sicht von Kunden stellt das Quietschen von Kfz-Bremsen einen erheblichen Qualitätsmangel dar und berechtigt unter bestimmten Voraussetzungen sogar zur Rückgabe des Fahrzeuges. Die Entwicklung geräuscharmer Bremsen ist im Allgemeinen keine triviale Aufgabe. Häufig kann das Quietschverhalten von neu entwickelten Kfz-Scheibenbremsen erst an Prototypen in au...

  13. Analyse des formes et modes traditionnels de communication en ...

    African Journals Online (AJOL)

    Analyse des formes et modes traditionnels de communication en milieu rural ... se situe aussi bien au niveau de la forme verbale que non verbale du langage. ... In fact, expressions of message take place in verbal and no verbal language.

  14. Idéal démocratique et idéal environnemental : analyse comparée des pouvoirs territoriaux en France et au Mexique

    OpenAIRE

    Mollard, Eric

    2009-01-01

    De nombreux programmes et réformes de protection environnementale sont voués à l’échec. Dans les pays en voie de développement, la situation est critique car programmes et réformes sont systématiquement détournés de leur objectif initial. Les formes de démocratie sont-elles en cause ? A travers une comparaison des processus qui freinent ou bloquent l’application de la volonté générale, nous discutons les conditions démocratiques propre à l’action environnementale. Nous sommes alors conduits à...

  15. Analysing and Comparing Encodability Criteria

    Directory of Open Access Journals (Sweden)

    Kirstin Peters

    2015-08-01

    Full Text Available Encodings or the proof of their absence are the main way to compare process calculi. To analyse the quality of encodings and to rule out trivial or meaningless encodings, they are augmented with quality criteria. There exists a bunch of different criteria and different variants of criteria in order to reason in different settings. This leads to incomparable results. Moreover it is not always clear whether the criteria used to obtain a result in a particular setting do indeed fit to this setting. We show how to formally reason about and compare encodability criteria by mapping them on requirements on a relation between source and target terms that is induced by the encoding function. In particular we analyse the common criteria full abstraction, operational correspondence, divergence reflection, success sensitiveness, and respect of barbs; e.g. we analyse the exact nature of the simulation relation (coupled simulation versus bisimulation that is induced by different variants of operational correspondence. This way we reduce the problem of analysing or comparing encodability criteria to the better understood problem of comparing relations on processes.

  16. Analyse comparative de la rentabilité des systèmes de production de coton biologique, conventionnel et transgénique au Burkina Faso

    Directory of Open Access Journals (Sweden)

    Vognan, G.

    2017-01-01

    Full Text Available Comparative Analysis of the Profitability of Organic, Conventional, and Transgenic Cotton Farming Systems in Burkina Faso. This research aimed to compare the profitability of cotton cropping systems (cotton and rotation crops according to three production modes: organic, conventional, and transgenic. The study was conducted in Burkina Faso on a sample of 180 households of which 60 households from organic cotton system, 60 households from conventional cotton system, and 60 households from transgenic cotton system. It came out that the production costs of the various crops in the transgenic and conventional systems are higher than those of the organic system. The differences in the production costs for the three modes of production are highly significant especially for cotton, corn, sorghum and groundnut. In terms of profitability, there's no significant difference in the margins generated by the different modes of cotton production. On the other hand, the sensitivity analysis revealed that organic cotton is financially more resilient to cotton price fluctuation and chemical inputs cost. Actually, organic cotton production seems to be a viable option to alleviate poverty in the present context of climate change.

  17. L'analyse des corpus multimodaux en ligne : état des lieux et perspectives

    Directory of Open Access Journals (Sweden)

    Develotte Christine

    2012-07-01

    Full Text Available Partant de l’ouvrage "Texte et ordinateur. L’écriture réinventée ?" de Jacques Anis (1998 nous cherchons à montrer la trajectoire des travaux français en sciences du langage sur les corpus médiés par la technologie jusqu’à aujourd’hui. La communication en ligne renvoie à des formes diverses selon qu’il s’agit de la production de textes fixes (par exemple, sites Web, courriels ou de formes plutôt centrées sur les processus d’interaction et de communication (par exemple, chat, visioconférence susceptibles donc d’être étudiées tant du point de vue de l’analyse du discours que de celui de l’analyse conversationnelle. Nous nous proposons de montrer, dans cet article, dans quelle mesure les deux traditions en sciences du langage ont trouvé matière à exploiter ces corpus en ligne en empiétant, parfois, l’une comme l’autre, sur leurs « territoires » respectifs. Dans cette perspective, nous commençons par mettre au jour l’apport des chercheurs revendiquant leur appartenance à l’analyse du discours, puis celui des chercheurs relevant de l’analyse des interactions et nous montrons les zones de tuilage entre les deux courants. Dans une dernière partie, nous nous intéressons aux défis juridiques, techniques et épistémologiques que doit relever le linguiste qui cherche à étudier des corpus multimodaux en ligne qui prennent des formes de plus en plus sophistiquées et complexes.

  18. RECRUTEMENT DES CIVELLES (ANGUILLA ANGUILLA SUR LA COTE MEDITERRANEENNE FRANÇAISE : ANALYSE COMPAREE DES CARACTERISTIQUES BIOMETRIQUES ET PIGMENTAIRES DES SAISONS 1974-75 ET 2000-01.

    Directory of Open Access Journals (Sweden)

    LEFEBVRE F.

    2003-07-01

    Full Text Available Une campagne d’échantillonnage des civelles Anguilla anguilla a été menée de novembre 2000 à mai 2001 au grau de la Fourcade (Saintes-Maries-de-la-Mer, côte méditerranéenne française. Des civelles ont été capturées sur toute la période d’échantillonnage, mais les maxima d’abondance se situent en janvier-février et, dans une moindre mesure, en avril. Afin d’optimiser le recrutement dans les lagunes littorales intérieures, la mesure de gestion proposée est donc de favoriser l’ouverture des martelières au milieu de l’hiver. Le suivi des proportions mensuelles des différents stades pigmentaires (de V A à VI A4 permet de conclure à un vieillissement généralisé des civelles en recrutement de novembre à mars, puis à l’arrivée d’un deuxième flux de civelles jeunes en avril. Parallèlement, il est observé une diminution très nette des masses et des longueurs moyennes mensuelles, et ce, même en ne considérant qu’un stade pigmentaire donné (en l’occurrence V B. Ces résultats sur l’évolution des caractéristiques biométriques et pigmentaires sont en accord avec les deux séries de travaux déjà menés sur la façade méditerranéenne française (années 30 et 70, ainsi qu’avec les données publiées en différents points de la façade atlantique. L’analyse comparée de ces données avec celles issues de la dernière étude en date sur la côte méditerranéenne française (Bages-Sigean, Languedoc-Roussillon, campagne 1974-75 ; LECOMTE-FINIGER, 1976 montre une composition pigmentaire mensuelle totalement différente, et révèle une diminution significative de la longueur des civelles, de l’ordre de 5 % en 25 ans.

  19. Analyse des cadres juridiques des aires marines protégées des pays ouest africains

    Directory of Open Access Journals (Sweden)

    Marie Cuq

    2013-06-01

    Full Text Available En analysant de manière transversale les droits nationaux relatifs aux aires protégées de sept pays d'Afrique de l'Ouest (le Cap Vert, la Gambie, la Guinée, la Guinée-Bissau, la Mauritanie, le Sénégal et la Sierra Leone, cette étude tend à apporter des éléments de connaissances de ces droits nationaux, tant sur le plan normatif qu'institutionnel, et à s'interroger sur le contenu, la mise en oeuvre et l'adaptabilité de ceux-ci à la lumière des enjeux environnementaux, sociaux et économiques de la sous-région ouest-africaine.

  20. Analyse de la distribution spatiale des Acanthaceae en Afrique ...

    African Journals Online (AJOL)

    Sci-Nat

    d'échantillons sont: Justicia Lin. avec 1595 échantillons (17,1% des échantillons; 58 espèces), Thunbergia Retz avec 813 échantillons. (8,7% des échantillons; 36 espèces), et. Asystasia Blume avec 638 échantillons (6,8% des échantillons; 11 espèces). La carte de distribution des. 9181 échantillons d'Acanthaceae (Fig.

  1. Interprétation de l'agir et saisie des dimensions didactiques dans l'analyse des pratiques enseignantes

    Directory of Open Access Journals (Sweden)

    Bulea Ecaterina

    2014-07-01

    Full Text Available Cette contribution examine dans quelle mesure et selon quelles modalités l’analyse de l’activité (ou des pratiques outillée, c’est-à-dire celle qui se déroule dans le cadre de dispositifs délibérément mis en place pour susciter chez les personnes un retour réflexif sur leur pratique, rend compte, saisit ou interprète (certaines des dimension proprement didactiques de l’activité enseignante. L’article est structuré en cinq parties. La première est centrée sur les principes généraux de l’analyse des pratiques et évoque les dispositifs méthodologiques actuellement en usage en ce domaine, en particulier : l’entretien d’explicitation (Vermersch, 1994, les instructions au sosie (Clot & Soubiran, 1999 ; Scheller, 2000, les auto-confrontations simple et croisée (Clot & Faïta, 2000 ; Clot, 2001 et les entretiens de recherche utilisés à des fins d’analyse des pratiques (Blanchet & Gotman, 1992 ; Bronckart & Groupe LAF, 2004. La deuxième partie précise le contexte de la recherche sur laquelle nous nous appuyons, le type de données examinées et le cadre méthodologique de recueil de ces données : il s’agit d’une recherche conduite auprès d’enseignants de FLE, qui enseignent dans trois types d’institutions contrastées, et qui ont été interviewés dans le cadre d’un dispositif combinant entretien de recherche et instructions au sosie. La troisième partie décrit la méthodologie d'analyse des données, inspirée du modèle de l'architecture textuelle élaboré dans le cadre de l'interactionnisme socio-discursif (Bronckart, 1997. La quatrième partie décrit les caractéristiques du processus d’interprétation par les enseignants de leur activité, en mettant en évidence les configurations interprétatives, ou les « figures d’action » (Bulea, 2010 qu’ils construisent dans leur discours, et en les contrastant avec celles constriutes par des infirmières. Enfin, la dernière partie examine de

  2. Analyse technico–économique des Aliments densifies sur les ...

    African Journals Online (AJOL)

    Une étude portant sur l'influence des aliments densifiés sur la performance de croissance des boucs roux de Maradi a été conduite entre juillet 2016 à septembre 2016. Quarante deux (42) boucs ont été répartis au hasard en six lots de sept individus. Chaque lot correspond à un aliment ou traitement préparé à partir des.

  3. Original Paper Analyses électrochimiques des eaux de pluie ...

    African Journals Online (AJOL)

    être aussi une source de maladies, car il véhicule d'innombrables substances chimiques telles que les ions ..... des ajouts dosés confirme l'absence des ions iodures dans les eaux de pluie, car aucun pic correspondant à ..... of car, truck, bus and subway wash station discharges to stormwater pollution (Toulouse, France).

  4. Analyse des politiques sur la grippe aviaire | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... à prévenir sa transmission à l'humain et à renforcer les mesures nationales de préparation en cas de pandémie de grippe aviaire. Le Partenariat de recherche sur l'influenza aviaire en Asie (APAIR) regroupe des organismes de recherche nationaux ainsi que des ministères de la Chine, du Cambodge, de l'Indonésie, ...

  5. Original Paper Analyse de l'évolution de l'occupation des terres à ...

    African Journals Online (AJOL)

    Au Burkina Faso, les contraintes climatiques couplées aux actions ... l'étude était d'évaluer l'état de dégradation du milieu et d'analyser les effets des mesures ... Dans la plupart des pays sahéliens ..... croisés sur le changement global et le.

  6. Analyse de la fiabilité des statistiques des pêcheries maritimes ...

    African Journals Online (AJOL)

    SARAH

    31 janv. 2016 ... SEDZRO Kossi Maxoe¹ *, FIOGBE Emile Didier¹, GUERRA Eduardo Balguerias², STAMATOPOULOS. Constantine³. ¹Laboratoire de Recherche sur les Zones Humides, Faculté des Sciences et des Techniques, Université d'Abomey-. Calavi, 01BP526 Cotonou Bénin, Tél. (229) 95268262. ²Institut Espagnol ...

  7. 98 Etude Comparative du Systeme Phonematique et Tonal des ...

    African Journals Online (AJOL)

    98. Etude Comparative du Systeme Phonematique et Tonal des. Deux Parlers: Le Yoruba du Nigeria et L'itsa Parle en. Republique du Benin. Ajani Akinwumi Lateef et Ayuba G. Ajibabi http://dx.doi./org/10.4314/ujah.v18i3.5. Résume. En ce début de l'époque ou la mondialisation et la coexistence des peuples dans le ...

  8. Analyse des mécanismes de transmission des infections sexuellement transmissibles

    OpenAIRE

    Abraham, Shahnaz

    2008-01-01

    Ce travail comprend une étude de l'épidémiologie des infections sexuellement transmissibles (IST) et du VIH à Genève et en Suisse. Nous constatons une recrudescence des IST pendant la période analysée 1999-2004, supersosable à la situation observée dans les autres métropoles européennes, tandis que l'incidence du VIH est restée stable. Nous analysons les facteurs importants pour la transmission des IST-VIH et soulignons l'importance de poursuivre les campagnes de prévention, visant non seulem...

  9. Repérage d’Images Ordinaires : Analyse des Requêtes des Chercheurs d’Images

    Directory of Open Access Journals (Sweden)

    Elaine Ménard

    2009-06-01

    also emphasizes the pressing necessity to optimize the methods used for image processing, in order to facilitate image retrieval and dissemination in multilingual environments. Résumé Depuis quelques années, le web est devenu un média incontournable pour la diffusion de ressources multilingues. Cependant, les différences linguistiques constituent souvent un obstacle majeur aux échanges de documents scientifiques, culturels, pédagogiques et commerciaux. En plus de cette diversité linguistique, on constate le développement croissant de bases de données et de collections composées de différents types de documents textuels ou multimédias, ce qui complexifie également le processus de repérage documentaire. Par exemple, les collections d’images numériques sont aussi nombreuses que diversifiées. Le besoin de repérer une image spécifique dans diverses collections est devenu une préoccupation partagée par plusieurs communautés. La croissance du web a mis en relief le besoin pressant de se doter d’outils propres à la description des images dans le but de faciliter leur repérage, puisque l’on retrouve celles-ci dans la plupart des ressources disponibles. Cette recherche compare le repérage d’images dans deux contextes linguistiques différents : un contexte monolingue, c’est-à-dire que la langue de la requête (français est la même que la langue d’indexation (français; et un contexte multilingue où la langue de la requête (français est différente de la langue d’indexation (anglais. Cet article présente les résultats de l’analyse des requêtes formulées par les participants pour repérer un ensemble d’images ordinaires représentant des objets de la vie quotidienne, en contexte de repérage multilingue. L’examen des termes contenus dans les requêtes des chercheurs d’images révèle les tendances observées sur le plan terminologique, perceptuel et structurel. Les participants emploient généralement des requêtes simples

  10. Approche SIG pour une analyse spatiale des infrastructures ...

    African Journals Online (AJOL)

    SARAH

    31 janv. 2014 ... SIG jouent un rôle primordial dans l'implantation, le suivi et la gestion des infrastructures hydrauliques. L'utilisation de ces outils peut atténuer les difficultés d'approvisionnement en eau. Mots clés : SIG, distribution spatiale, infrastructure hydraulique, Zè, Bénin. ... accès à un dispositif d'assainissement de.

  11. Analyse sexospécifique et générationnelle des conflits armés et des ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Les phases antérieures ont été financées dans le cadre du projet no 102081, Questions de genre et de génération dans les conflits armés, les processus de paix et de justice et le désarmement, et du projet no 103312, Analyse sexospécifique et générationnelle des conflits armés et des processus de paix et de justice ...

  12. Usages des technologies par les élèves professeurs : analyse à partir de questionnaires

    Directory of Open Access Journals (Sweden)

    Philippe Le Borgne

    2005-01-01

    Full Text Available Cet article étudie l’appropriation et les usages des technologies chez les élèves professeurs français. La méthodologie utilisée est basée sur l’analyse de réponses à des questionnaires soumis aux professeurs stagiaires de quatre instituts universitaires de formation des maîtres. Les résultats obtenus tendent à prouver que les enseignants en formation sont aujourd’hui bien équipés et disposent de compétences réelles dans le cadre des usages personnels et professionnels en dehors de la classe. Cependant, il apparaît que ces compétences sont peu mobilisées dans le cadre des usages en classe.

  13. La Vie de Marillac : un essai hagiographique ? Analyse comparée des sources utilisées par Nicolas Lefèvre de Lezeau dans la Vie de Marillac et la Vie de Morvillier

    Directory of Open Access Journals (Sweden)

    Dora De Lima

    2012-01-01

    Full Text Available Considérer Nicolas Lefèvre de Lezeau comme le biographe de son grand oncle ou comme l’hagiographe de son ami Michel de Marillac revient à glorifier la mémoire des trois héros au détriment du projet d’écriture de l’auteur. La Vie de Jean de Morvillier et la Vie de Michel de Marillac sont vivement marquées par l’omniprésence de leur auteur, quand bien même l’illusion de la richesse documentaire sur les trois héros voudrait l’estomper. Parce qu’ils convoquent une documentation riche et de nombreuses références littéraires, les trois récits de vie retrouvés témoignent d’une quête d’authenticité par leur auteur. En ce sens, la Vie de Marillac se dégage des deux autres récits de vie écrits par Lezeau. Le conseiller d’état n’y cherche effectivement pas seulement à raviver la mémoire de la Ligue dans le milieu dévot, ni même à construire une filiation entre ces deux partis. L’originalité de la Vie de Marillac tient de l’abondance des références spirituelles et de l’autorité que les mystiques incarnent pour sa validation. Pour les mystiques, la vie chargée d’un officier d’état demeure incompatible avec le mode de vie humble et contemplatif d’un « petit ». Du côté des politiques, la « cabale des dévots » représente une menace croissante pour l’autorité du roi. Dès lors, la Vie de Marillac de Lezeau nous invite à réfléchir sur les caractéristiques de rejet d’un modèle de sainteté (E. Suire. La postérité retient Marillac pour sa témérité et sa faillite face à la raison d’état de Richelieu, comme l’attestent le peu de biographies des xixe-xxe siècles de ce garde des sceaux. Parallèlement, si Marillac est décrit comme un laïc ayant fait preuve d’une grande dévotion dans les Histoires de l’ordre des Carmélites déchaussées parues aux xixe et xxe siècles, sa part active à la fondation de l’ordre en France ne suffit pas à faire de lui un saint

  14. Analyse des solides déformables par la méthode des éléments finis

    CERN Document Server

    Bonnet, Marc

    2006-01-01

    Cet ouvrage propose une présentation structurée de la formulation et la mise en œuvre de la simulation numérique par éléments finis en mécanique des solides déformables. Il présente et développe les concepts et techniques permettant la transposition, en termes de codes de calcul de structures mécaniques industrielles, des notions fondamentales de mécanique des milieux continus solides, et ce dans le cadre d'analyses en régimes (a) statique linéaire, (b) quasistatique non-linéaire et (c) dynamique linéaire. L'exposé théorique est complété et illustré au moyen de programmes d'initiation écrits en Matlab (librement accessibles par Internet) mettant en œuvre les notions développées dans cet ouvrage et conçus comme support pratique à un enseignement. Le texte combine ainsi l'exposition des principes et des méthodes avec la présentation détaillée de ces programmes et d'exemples les mettant en œuvre. L'ouvrage est complété d'une annexe écrite par Andrei Constantinescu (directeur de...

  15. Renforcement des capacités en analyse des politiques et systèmes ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Depuis 2005, la Fondation Bill et Melinda Gates a financé le programme de Maîtrise en santé et population à l'Institut supérieure des sciences de la population (ISSP) de l'Université de Ouagadougou, Burkina Faso. Cependant, après la formation de cinq cohortes dans le cadre du programme, il est apparu nécessaire de ...

  16. Analyse des facteurs prédictifs de malignité des goitres nodulaires : à propos de 500 cas

    Science.gov (United States)

    Bouaity, Brahim; Darouassi, Youssef; Chihani, Mehdi; Touati, Mohamed Mliha; Ammar, Haddou

    2016-01-01

    Les nodules thyroïdiens sont très fréquents et moins de 10% d'entre eux sont malin. Ils posent un véritable problème diagnostique et thérapeutique surtout par rapport à leur nature bénigne ou maligne. L’étude de certains facteurs cliniques et paracliniques de présomption de malignité permet de bien codifier la stratégie thérapeutique. Le but de ce travail est d’étudier les facteurs prédictifs de malignité des goitres nodulaires et comparer nos résultats à ceux de la littérature. Il s'agit d'une étude rétrospective à propos de 500 cas de goitres nodulaires opérés au service d'Oto-rhino-laryngologie (ORL) et Chirurgie cervico-faciale (CCF) de l'hôpital militaire Avicenne de Marrakech entre 2006 et 2012. Le pourcentage de cancers a été de 6,8%. L’âge moyen de nos patients était de 46 ans, avec une sex-ratio de 5 (F/H). A la palpation cervicale; le caractère dure du nodule a été constaté dans 94,4% des cas de cancer, avec des limites irrégulières dans 64,70% des cas de cancer. Trois nodules étaient fixes et ils étaient tous malins. Les adénopathies cervicales ont été constatées chez 8 malades dont 7 présentaient des cancers. A l’échographie, 61,8% des nodules malins présentaient un aspect hypoéchogène, avec des contours flous dans 88,24% des cas. La vascularisation intra nodulaire était présente dans 35,3% de ces cas des cancers avec des microcalcifications chez 55,9% d'entre eux. Le halo hypoéchogene périnodulaire était incomplet dans 73,5% des cas de cancer. Nos patients étaient en euthyroïdie dans 84,6% des cas. Les facteurs prédictifs de malignité d'un goitre nodulaire, étaient donc dans notre étude d'abord cliniques: l’âge supérieur à 60 ans, la consistance dure du nodule, sa fixité, son caractère irrégulier et mal limité à la palpation, ainsi que la présence d'adénopathie(s) cervicale(s) à l'examen; et échographiques: le caractère hypoéchogène, les limites floues, la présence de

  17. L'image des Fulbe : analyse critique de la construction du concept de 'pulaaku'

    NARCIS (Netherlands)

    Breedveld, A.; Bruijn, de M.E.

    1996-01-01

    Peut-on considérer que les Fulbe forment un peuple unique, malgré leur dispersion, dans la mesure où ils partagent la même langue? En comparant le discours des anthropologues et des linguistes à propos du concept de 'pulaaku', les auteurs soulèvent la question de la complexité qu'il y a à définir

  18. L'analyse des risques l'expert, le décideur et le citoyen

    CERN Document Server

    Chevassus-au-Louis, Bernard

    2007-01-01

    Selon le modèle "standard" d'analyse du risque, utilisé majoritairement aujourd'hui, les experts basent leurs pratiques sur des hypothèses, des concepts, voire des valeurs implicites qui ne peuvent être considérées comme des évidences. La fin du XXe siècle a marqué une crise de l'expertise. Progressivement s'est instauré un débat autour du principe de précaution, principe dont l'application a des conséquences pour la décision et pour l'évaluation du risque lui-même. De son côté, la société civile a un rôle participatif fort à jouer. Se dessinent ainsi les contours d'une analyse de risque "postmoderne", dite "constructiviste", qu'il s'agit de mettre à l'épreuve concrètement.

  19. L’analyse des passions dans la dissolution du corps politique : Spinoza et Hobbes

    Directory of Open Access Journals (Sweden)

    Julie Saada-Gendron

    2005-09-01

    Full Text Available Les théories contractualistes de l’âge classique se fondent sur la conception d’un état de nature qui devient, à cause de ses contradictions internes, un état de guerre auquel il faut remédier par un artifice rationnel, le pacte. Alors même que ces contradictions sont issues des passions humaines, celles-ci semblent impensables dans le cadre purement juridique de ces théories, où ne sont analysés ni les mécanismes passionnels d’adhésion au politique, ni la menace de dissolution de l’État. Nous nous attachons à comparer le rôle que Hobbes et Spinoza font jouer aux passions dans l’élaboration de leurs doctrines politiques : tandis que Hobbes témoigne d’un souci constant des passions, tout en les mettant à l’écart lorsqu’il s’agit de penser la construction et le fonctionnement de l’édifice politique, Spinoza permet de penser deux groupes de passions – celles qui résistent nécessairement au corps politique et celles qui lui font obstacle ponctuellement. Ces dernières constituent tout à la fois des facteurs de décomposition et de recomposition du corps collectif. Cette approche du politique à partir des causes de sa dissolution permet d’apporter un éclairage à la signification du droit naturel moderne tel qu’il se construit chez Hobbes et chez Spinoza.The contractualist theories of the Classical Age are grounded on the conception of a state of nature which becomes, because of its internal contradictions, a state of war to which the only remedy is a rational artifice : the pact. Although these contradictions arise from human passions, passions seem to be unthinkable in the strictly juridical frame of these theories, where neither the passional mechanisms of political adhesion, nor the menace of the dissolution of the State, are analysed. We will strive to compare the role that Hobbes and Spinoza attribute to passions in their respective political doctrines. Whereas Hobbes shows a constant

  20. Comparative sequence analyses of genome and transcriptome ...

    Indian Academy of Sciences (India)

    2015-12-04

    Dec 4, 2015 ... 2011), unique vocal communication. (Payne 2003; Nair et al. ... induction of apoptosis when compared to human cells. In this study, we have .... based on calculated Pearson correlation and displayed based on centroid of the ...

  1. Comparative analyses of bidirectional promoters in vertebrates

    Directory of Open Access Journals (Sweden)

    Taylor James

    2008-05-01

    Full Text Available Abstract Background Orthologous genes with deep phylogenetic histories are likely to retain similar regulatory features. In this report we utilize orthology assignments for pairs of genes co-regulated by bidirectional promoters to map the ancestral history of the promoter regions. Results Our mapping of bidirectional promoters from humans to fish shows that many such promoters emerged after the divergence of chickens and fish. Furthermore, annotations of promoters in deep phylogenies enable detection of missing data or assembly problems present in higher vertebrates. The functional importance of bidirectional promoters is indicated by selective pressure to maintain the arrangement of genes regulated by the promoter over long evolutionary time spans. Characteristics unique to bidirectional promoters are further elucidated using a technique for unsupervised classification, known as ESPERR. Conclusion Results of these analyses will aid in our understanding of the evolution of bidirectional promoters, including whether the regulation of two genes evolved as a consequence of their proximity or if function dictated their co-regulation.

  2. Analyse des images satellitales radar RSO-ERS et optique ETM+ de ...

    African Journals Online (AJOL)

    ... l'analyse des images satellitales est un outil¸ au même titre que par exemple, la géophysique de prospection minière. Les spatio-cartes géologiques obtenues peuvent permettre de mieux planifier les travaux miniers sur le terrain. Mots-clés : images satellitales, Radar RSO-ERS, ETM+ - LANDSAT 7, prospection minière, ...

  3. Analyses des taxes et de la pauvreté pour faire avancer la lutte ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Analyses des taxes et de la pauvreté pour faire avancer la lutte contre le tabagisme à l'échelle mondiale. Ce projet, mis en place par l'Instituto Nacional de Salud Pública du Mexique, consiste à entreprendre une série d'études préliminaires pour contribuer aux travaux de la nouvelle commission sur la lutte antitabac à ...

  4. Arbeitszufriedenheit und flexible Arbeitszeiten – Empirische Analyse mit Daten des Sozio-oekonomischen Panels

    OpenAIRE

    Dominik Hanglberger

    2010-01-01

    Ziel dieser Analyse ist die Identifikation von Auswirkungen unterschiedlicher flexibler Arbeitszeitformen und Abgeltungsarten von Überstunden auf die subjektive Arbeitszufriedenheit. Dazu wird zunächst die Verbreitung flexibler Arbeitszeitformen in Deutschland im Zeitverlauf beschrieben. Auf Basis von Daten der Jahre 2005 und 2007 des Soziooekonomischen Panels (SOEP) wird ein Fixed-Effects Panelmodell geschätzt. Es zeigt sich ein positiver Effekt von selbst bestimmten Arbeitszeiten auf die Ar...

  5. Arbeitszufriedenheit und flexible Arbeitszeiten:empirische Analyse mit Daten des Sozio-oekonomischen Panels

    OpenAIRE

    Hanglberger, Dominik

    2010-01-01

    Ziel dieser Analyse ist die Identifikation von Auswirkungen unterschiedlicher flexibler Arbeitszeitformen und Abgeltungsarten von Überstunden auf die subjektive Arbeitszufriedenheit. Dazu wird zunächst die Verbreitung flexibler Arbeitszeitformen in Deutschland im Zeitverlauf beschrieben. Auf Basis von Daten der Jahre 2005 und 2007 des Soziooekonomischen Panels (SOEP) wird ein Fixed-Effects Panelmodell geschätzt. Es zeigt sich ein positiver Effekt von selbst bestimmten Arbeitszeiten auf die Ar...

  6. Die Analyse der Wertschöpfungskette Schweinefleisch unter den Aspekten des Supply Chain Management

    OpenAIRE

    Schönberger, Wolfgang

    2008-01-01

    Inhalt der Arbeit ist die vergleichende Analyse der Wertschöpfungskette Schweinefleisch unter den Aspekten des Supply Chain Management für Bayern sowie für Dänemark als dem weltweit größten Nettoexporteur von Schweinefleisch. Wichtige Wettbewerbsfaktoren und die Strukturen der Wertschöpfungskette werden untersucht. Die Produktionskosten werden nach der Methode der Vollkostenrechnung ermittelt. In Dänemark haben sich auf allen Stufen der Wertschöpfungskette Strukturen entwickelt, die die...

  7. Analyse conceptuelle et traductibilité des termes de maladie dioula

    NARCIS (Netherlands)

    Diaby Kassamba, Oumou Koultoum

    2015-01-01

    Ce livre est une étude pionnière portant sur l’analyse conceptuelle et la traductibilité des termes de maladie dioula jusqu’ici non abordées par les recherches antérieures. Le Dioula est une langue mandé parlée au Burkina Faso. L’étude présente les représentations de la santé, de la maladie et du

  8. International comparative analyses of healthcare risk management.

    Science.gov (United States)

    Sun, Niuyun; Wang, Li; Zhou, Jun; Yuan, Qiang; Zhang, Zongjiu; Li, Youping; Liang, Minghui; Cheng, Lan; Gao, Guangming; Cui, Xiaohui

    2011-02-01

    Interpretation of the growing body of global literature on health care risk is compromised by a lack of common understanding and language. This series of articles aims to comprehensively compare laws and regulations, institutional management, and administration of incidence reporting systems on medical risk management in the United Kingdom, the United States, Canada, Australia, and Taiwan, so as to provide evidence and recommendations for health care risk management policy in China. We searched the official websites of the healthcare risk management agencies of the four countries and one district for laws, regulatory documents, research reports, reviews and evaluation forms concerned with healthcare risk management and assessment. Descriptive comparative analysis was performed on relevant documents. A total of 146 documents were included in this study, including 2 laws (1.4%), 17 policy documents (11.6%), 41 guidance documents (28.1%), 37 reviews (25.3%), and 49 documents giving general information (33.6%). The United States government implemented one law and one rule of patient safety management, while the United Kingdom and Australia each issued professional guidances on patient safety improvement. The four countries implemented patient safety management policy on four different levels: national, state/province, hospital, and non-governmental organization. The four countries and one district adopted four levels of patient safety management, and the administration modes can be divided into an "NGO-led mode" represented by the United States and Canada and a "government-led mode" represented by the United Kingdom, Australia, and Taiwan. © 2011 Blackwell Publishing Asia Pty Ltd and Chinese Cochrane Center, West China Hospital of Sichuan University.

  9. Les conditions d'exploitation et d'analyse des pratiques pour la formation des enseignants

    Directory of Open Access Journals (Sweden)

    Jean-Paul Bronckart

    2010-01-01

    Full Text Available Two different approaches currently dominate the teacher training field. One consists in the traditional transmission of knowledge and generally takes the form of conventional classroom teaching. The other, more recent and emerging from the domain of work sciences, consists in different methods for analysing teaching practices (interviews, peer instruction, self-confrontation, etc. so that future teachers can be confronted with real-life situations and become aware of some of the characteristics of the profession they have chosen.The first part of this article examines the conditions and reasons for the emergence of practice analysis in teacher training, starting with the example of the recent evolution in the field of mother tongue didactics. The second part presents a critical assessment and balance of this evolution. On the one hand, it highlights the need for a deep change in the “logic” underlying innovative initiatives in the field; on the other hand, it formulates proposals to redefine teacher training objectives and methods by focussing on a close association between the classical methods of knowledge transmission and the more recent methods of teaching practice analysis. The third part analyses the characteristics of some of the methods used in teaching practice analysis, focussing on the nature of their “objects”, their intelligibility, and the role they play in raising trainees’ awareness about their own development. Finally, the last part of the article is devoted to trainees’ own verbal production during practice analysis, with a view to highlighting the discursive processes used by trainees to (reconstruct the meaning of their activity, which in turn leads them to question the very conditions under which teaching practice analysis truly contributes to their personal and professional development.

  10. Comment constituer et traiter des corpus issus des médias sociaux à l’aide des CAQDAS? NVivo : un instrument pour l’analyse des discours numériques

    Directory of Open Access Journals (Sweden)

    Ferrari Giovannipaolo

    2015-01-01

    Full Text Available Avec l’apparition des médias sociaux, le chercheur en Sciences Humaines et Sociales a vu s’ouvrir des possibilités de création de corpus à partir des données disponibles en ligne. Le risque dans ces modalités de création de corpus est de créer de grandes bases de données difficilement gérables avec les outils traditionnels et surtout dans le cadre d’une recherche qualitative. Pour cette raison, il semble important de mobiliser des outils numériques pour l’aide à la recherche. Ces logiciels sont appelés CAQDAS. Cette contribution montre comment les utiliser pour une enquête de terrain en ligne ou numérique afin d’organiser et d’analyser un corpus. Ce corpus est constitué en vue d’une analyse des discours produits dans le contexte professionnel de la radio utilisant les nouveaux médias.

  11. Review: Findeisen, Genia: Frauen in Indonesien: Geschlechtergleichheit durch Demokratisierung? Eine Analyse des Demokratisierungsprozesses aus Frauenperspektive (2008 Buchbesprechung: Findeisen, Genia: Frauen in Indonesien: Geschlechtergleichheit durch Demokratisierung? Eine Analyse des Demokratisierungsprozesses aus Frauenperspektive (2008

    Directory of Open Access Journals (Sweden)

    Carola von der Dick

    2009-04-01

    Full Text Available Review of the monograph: Findeisen, Genia: Frauen in Indonesien: Geschlechtergleichheit durch Demokratisierung? Eine Analyse des Demokratisierungsprozesses aus Frauenperspektive Wettenberg: Johannes Herrmann J&J Verlag, 2008, ISBN 978-3-937983-11-0, 434 pages Besprechung der Monographie: Findeisen, Genia: Frauen in Indonesien: Geschlechtergleichheit durch Demokratisierung? Eine Analyse des Demokratisierungsprozesses aus Frauenperspektive Wettenberg: Johannes Herrmann J&J Verlag, 2008, ISBN 978-3-937983-11-0, 434 Seiten

  12. Ideen zu einer Literatursoziologie des Internets. Mit einer Blogotop-Analyse

    Directory of Open Access Journals (Sweden)

    Peer Trilcke

    2013-11-01

    Full Text Available Der Essay skizziert und exemplifiziert die Möglichkeiten einer Literatursoziologie des Internets und plädiert in diesem Zusammenhang für eine Empirisierung der Forschung zu diesem rasant wachsenden, jedoch bisher in seiner Differenziertheit allenfalls oberflächlich beschriebenen Feld der Kommunikation über Literatur. Hierzu werden die literaturwissenschaftlichen Internet Studies und ihr literatursoziologischer Teilbereich innerhalb der allgemeinen Digital Humanities verortet. Als Beispiel für eine in diesem Sinne relational-empirische Literatursoziologie des Internets werden erste Ergebnisse der Analyse eines sog. Bücherblogotops präsentiert, anhand derer sich einige Mechanismen der sekundären literarischen Kommunikation zwar nicht repräsentativ, aber doch exemplarisch diskutieren lassen.

  13. Le CRDI « analyse l'autonomisation des femmes » lors d'une ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    14 mars 2018 ... ... discuter des défis associés à l'amélioration de l'autonomie des femmes, de leurs moyens d'expression et du bien-être des membres de leur foyer au travail, dans la société civile et dans les politiques nationales. Des universitaires, des praticiens du développement et des décideurs politiques discuteront ...

  14. Comparison of some methods for analyzing the optical properties of molecular aggregates; Comparaison de quelques methodes d'analyse des proprietes optiques des agregats moleculaires

    Energy Technology Data Exchange (ETDEWEB)

    Thiery, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1965-07-01

    This report compares the application both of the exciton theory and of the polarizability theory to the study of the optical properties of dimers made up of two identical molecules having only one excited level when separate, and which are held together in the dimer only by Van der Waals forces to the exclusion of any covalent bonding. Using this theoretical basis, the author gives an interpretation of the changes in the spectrum of aqueous NN' diethyl-cyanine solutions as a function of concentration, and stresses the present lack of experimental data necessary for understanding of the mechanism of the hypochromia of nucleic acids. (author) [French] Ce rapport compare l'application, d'une part de la theorie des excitons, d'autre part de la theorie des polarisabilites a l'etude des proprietes optiques de dimeres composees de deux molecules identiques ne possedant, lorsqu'elles sont prises isolement, qu'un seul niveau excite, et qui sont unies l'une a l'autre, au sein du dimere, par des forces de Van der Waals a l'exclusion de toute liaison covalente. Sur ces bases theoriques, l'auteur donne une interpretation de l'evolution du spectre de solutions aqueuses de NN' diethylcyanine en fonction de la concentration et souligne l'insuffisance actuelle des donnees experimentales necessaires a la comprehension du mecanisme de l'hypochromisme des acides nucleiques. (auteur)

  15. An approach to automated chromosome analysis; Etudes pour une methode d'automatisation des analyses chromosomiques

    Energy Technology Data Exchange (ETDEWEB)

    Le Go, Roland

    1972-05-03

    d'une automatisation des differentes etapes de l'analyse chromosomique. Il est divise en trois tomes dont la matiere est decrite ci-apres. Dans le tome 1 est decrite l'etude d'un selecteur automatique de metaphases. Cet appareil doit realiser au cours du scanning d'une preparation, un processus de decision aboutissant a rejeter toutes images ininteressantes et a conserver les images pertinentes (bonnes metaphases). Ce probleme a ete aborde au moyen d'une etude sur ordinateur par un programme de simulation. La realisation de ce programme a permis d'etablir des algorithmes de selection dont la replique pourra etre realisee dans des circuits logiques electroniques. Dans le tome 2 est traite le probleme de l'automatisation de l'etude morphologique des chromosomes presents dans une metaphase. Cette automatisation necessite le traitement des photographies de metaphases par un appareil convertisseur optique-numerique qui extrait l'information-image et la transcrit sous la forme d'un fichier numerique. Ce fichier comporte pour une image de metaphase, environ 200 000 valeurs de gris, codees selon une echelle a 16, 32 ou 64 ni veaux. Ce fichier numerique est traite par un programme de reconnaissance de forme, qui isole les chromosomes et en recherche les traits caracteristiques: sommets de bras et region centromerique, dans le but d'obtenir des mensurations equivalentes aux longueurs des quatre bras. Le tome 3 etudie un programme d'etablissement automatique du caryotype humain, par appariement optimise des chromosomes. Les donnees proviennent de la numerisation directe des longueurs de bras, effectuee au moyen d'un lecteur digital BENSON. Le programme etablit une liste des appariements, un document graphique imprime representant les paires constituees, dans l'espace: longueur - index centromerique; enfin un document graphique obtenu sur traceur BENSON dans lequel l'auteur donne une representation personnelle des chromosomes, sous forme de croix a bras orthogonaux, dont chaque

  16. Problems of method of technology assessment. A methodological analysis; Methodenprobleme des Technology Assessment; Eine methodologische Analyse

    Energy Technology Data Exchange (ETDEWEB)

    Zimmermann, V

    1993-03-01

    The study undertakes to analyse the theoretical and methodological structure of Technology Assessment (TA). It is based on a survey of TA studies which provided an important condition for theoreticall sound statements on methodological aspects of TA. It was established that the main basic theoretical problems of TA are in the field of dealing with complexity. This is also apparent in the constitution of problems, the most elementary and central approach of TA. Scientifically founded constitution of problems and the corresponding construction of models call for interdisciplinary scientific work. Interdisciplinarity in the TA research process is achieved at the level of virtual networks, these networks being composed of individuals suited to teamwork. The emerging network structures have an objective-organizational and an ideational basis. The objective-organizational basis is mainly the result of team composition and the external affiliations of the team members. The ideational basis of the virtual network is represented by the team members` mode of thinking, which is individually located at a multidisciplinary level. The theoretical `skeleton` of the TA knowledge system, which is represented by process knowledge based linkage structures, can be generated and also processed in connection with the knowledge on types of problems, areas of analysis and procedures to deal with complexity. Within this process, disciplinary knowledge is a necessary but not a sufficient condition. Metatheoretical and metadisciplinary knowledge and the correspondingly processes complexity of models are the basis for the necessary methodological awareness, that allows TA to become designable as a research procedure. (orig./HP) [Deutsch] Die Studie stellt sich die Aufgabe, die theoretische und methodische Struktur des Technology Assessment (TA) zu analysieren. Sie fusst auf Erhebungen, die bei Technology-Assessment-Studien vorgenommen wurden und die wesentliche Voraussetzungen fuer

  17. Analyse chronometrique intersexes de la resolution de la tache d'horizontalite des liquides

    Science.gov (United States)

    Berthiaume, Francois

    'ecart intersexes disparait si l'analyse tient compte de cette connaissance. Sur le plan du temps de reponse, les deux sexes ne se distinguent que lors du trace de la surface de l'eau dans un contenant incline, les garcons reflechissant alors plus longtemps. Le temps mis a produire, puis a verifier un trace, ne differe pas selon le sexe des participants. Dans l'evaluation de l'orientation d'une ligne cependant, les filles ne se distinguent pas des garcons et les participants connaissant le principe d'invariance reussissent mieux que ceux l'ignorant. Par ailleurs, les filles procedent toujours moins rapidement que les garcons. Pour les contenants inclines ou a l'horizontale, si la ligne represente la surface de l'eau, la difference intersexes est annulee quand la connaissance du principe est prise en compte. (Abstract shortened by UMI.)

  18. Pour le plaisir de la chose : analyse de contenu des conceptions et des usages du Kâmasûtra dans l'Occident contemporain

    OpenAIRE

    Robidas, Josiane

    2010-01-01

    Ce mémoire a pour but de retracer comment le Kāmasūtra, traité classique hindou sur l'art de vivre et d'aimer, est présenté et véhiculé dans l'Occident depuis sa première traduction, tant pour son interprétation, sa diffusion et sa réception que pour ce qu'il permet comme regards sur les représentations des sexualités occidentales. L'analyse de contenu a été faite à partir d'un corpus très hétérogène, contenant à la fois des traductions, des ouvrages scientifiques (qui permettent notamment la...

  19. Paternité des articles et intérêts concurrents : une analyse des recommandations aux auteurs des journaux traitant de pratique pharmaceutique

    Science.gov (United States)

    Courbon, Ève; Tanguay, Cynthia; Lebel, Denis; Bussières, Jean-François

    2014-01-01

    RÉSUMÉ Contexte : La présence d’auteurs honorifiques et fantômes ainsi que les intérêts concurrents représentent des difficultés bien documentées, liées à la publication d’articles scientifiques. Il existe des lignes directrices encadrant la rédaction et la publication de manuscrits scientifiques, notamment celles de l’International Committee of Medical Journal Editors (ICMJE). Objectifs : L’objectif principal de cette étude descriptive et transversale visait à recenser les instructions portant sur la paternité des articles et les intérêts concurrents provenant des recommandations aux auteurs des journaux traitant de pratique pharmaceutique. L’objectif secondaire visait à déterminer des mesures correctrices pour une paternité des articles plus transparente. Méthode : La recherche a débuté par l’identification des journaux traitant de pratique pharmaceutique. La consultation des instructions aux auteurs des journaux a permis ensuite de recenser les recommandations destinées à éviter les problèmes de paternité des articles et d’intérêts concurrents. Finalement, les membres de l’équipe de recherche se sont consultés afin de définir des mesures correctrices possibles à l’intention des chercheurs. Résultats : Des 232 journaux traitant de pharmacie, 33 ont été définis comme traitant de pratique pharmaceutique. Un total de 24 (73 %) journaux mentionnaient suivre la politique de l’ICMJE, 14 (42 %) demandaient aux auteurs de remplir un formulaire de déclaration d’intérêts concurrents au moment de la soumission de l’article, 17 (52 %) présentaient une définition de la qualité d’auteur et 5 (15 %) demandaient de détailler les contributions de chaque auteur. Une grille de 40 critères a été élaborée pour définir l’attribution du statut d’auteur. Conclusion : Moins de la moitié des journaux demandait aux auteurs de transmettre un formulaire de déclaration des intérêts concurrents au moment de la

  20. Analyse de L'ancrage des Vortex Intergrains pour le Yttrium BARYUM(2) CUIVRE(3) OXYGENE(7) Polycristallin

    Science.gov (United States)

    Fournier, Patrick

    Le Modele de l'Etat Critique Generalise (MECG) est utilise pour decrire les proprietes magnetiques et de transport du YBa_2Cu_3O _7 polycristallin. Ce modele empirique permet de relier la densite de courant critique a la densite de lignes de flux penetrant dans la region intergrain. Deux techniques de mesures sont utilisees pour caracteriser nos materiaux. La premiere consiste a mesurer le champ au centre d'un cylindre creux en fonction du champ magnetique applique pour des temperatures comprises entre 20 et 85K. En variant l'epaisseur de la paroi du cylindre creux, il est possible de suivre l'evolution des cycles d'hysteresis et de determiner des champs caracteristiques qui varient en fonction de cette dimension. En utilisant un lissage des resultats experimentaux, nous determinons J _{co}, H_ {o} et n, les parametres du MECG. La forme des cylindres, avec une longueur comparable au diametre externe, entrai ne la presence d'un champ demagnetisant qui peut etre inclus dans le modele theorique. Ceci nous permet d'evaluer la fraction du volume ecrante, f _{g}, ainsi que le facteur demagnetisant N. Nous trouvons que J_{ co}, H_{o} et f_{g} dependent de la temperature, tandis que n et N (pour une epaisseur de paroi fixe) n'en dependent pas. La deuxieme technique consiste a mesurer le courant critique de lames minces en fonction du champ applique pour differentes temperatures. Nous utilisons un montage que nous avons developpe permettant d'effectuer ces mesures en contact direct avec le liquide refrigerant, i.e. dans l'azote liquide. Nous varions la temperature du liquide en variant la pression du gaz au-dessus du bain d'azote. Cette methode nous permet de balayer des temperatures entre 65K et la temperature critique du materiau ({~ }92K). Nous effectuons le lissage des courbes de courant critique en fonction du champ applique encore a l'aide du MECG, pour a nouveau obtenir ses parametres. Pour trois echantillons avec des traitements thermiques differents, les parametres

  1. Étude comparative des transferts financiers intergouvernementaux ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Aux Philippines, on estime à 14 % la proportion d'écoliers qui souffrent de malnutrition aiguë. Les écoles offrent des voies stratégiques et ciblées pour fournir une alimentation nutritive aux enfants et, indirectement, à leurs familles et leurs collectivités. Un projet de recherche d'une durée de trois ans (de 2012 à 2015) a mis ...

  2. Analysis of solids by spark-source mass spectrometry; Analyse des solides au spectrometre de masse a etincelles

    Energy Technology Data Exchange (ETDEWEB)

    Stefani, R; Desjardins, M; Brun, J C; Cornu, A; Bourguillot, R [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1965-07-01

    Spark source mass spectrometer MS7 has been designed to determine traces of impurities in solids without standards. An atlas of 12 000 lines, assembled in the Grenoble laboratory, allows a quick investigation of mass spectra, notwithstanding their complexity due to multiply charged and polyatomic darkening. Photometric measurements increase accuracy calibration curve is known for each photo-plate. Further, reproducibility is better, if random fluctuations of matrix line darkening are corrected. So far, in a concentration range of 0,01 to 1 000 ppm (atomic), reproducibility is approximately 20 per cent, but absolute value of results depends on 'sensitivity coefficients'. (authors) [French] Le spectrometre de masse a etincelles, de type MS7, est destine a l'analyse chimique de traces dans les solides, sans echantillons etalons. L'emploi de catalogues de 12 000 raies, elabores au laboratoire, permet un depouillement rapide des spectres, malgre leur complexite due aux ionisations multiples et aux associations d'atomes. Le niveau d'apparition d'une impurete donne une estimation de sa teneur, mais la valeur du renseignement depend de la preparation des electrodes et de la connaissance plus ou moins approfondie des processus d'ionisation dans l'etincelle et de noircissement des emulsions photographiques. Les mesures photometriques augmentent la precision des resultats, si l'on determine systematiquement la courbe de noircissement de chaque plaque. De meme la reproductibilite est amelioree si l'on tient compte des fluctuations statistiques du noircissement de l'emulsion par les ions de la matrice. Actuellement, les concentrations mesurees dans le domaine de 0,01 a 1000 ppm atomiques sont reproductibles a 20 pour cent pres, mais leur valeur absolue n'est assuree qu'a un coefficient 3 pres. Des etudes sont en cours pour calibrer l'appareil en valeur absolue, par une determination des coefficients de sensibilite a partir d'echantillons etalons. (auteurs)

  3. Analyse Pharmaceutique de la prescription des antibiotiques au service des brules et chirurgie plastique de l'Hopital Militaire d'Instruction Mohammed V, Maroc

    Science.gov (United States)

    Benziane, H.; Karfo, R.; Siah, S.; Taoufik, J.

    2011-01-01

    Summary L'infection est longtemps restée la principale cause de mortalité chez le brûlé grave. Ce travail a pour but d'évaluer la prescription des antibiotiques dans notre Service des Brûlés et Chirurgie Plastique, au regard du dossier d'autorisation de mise sur le marché (Résumé des caractéristiques du produit). Tous les patients sous antibiothérapie, au Service des Brûlés et Chirurgie Plastique de l'Hôpital Militaire d'Instruction Mohammed V de Rabat, Maroc, durant la période janvier 2008/mai 2009, ont été inclus. Il s'agit d'une étude rétrospective qui a analysé 41 dossiers de patients. Les antibiotiques utilisés par le service appartiennent à différentes familles. Les plus utilisés sont les bêta-lactamines (65%), glycopeptides (10,5%), aminosides (9%), quinolones (7%) et colistine (4,3%), avec 4,2% pour les autres classes d'antibiotiques (métronidazole 500 mg en perfusion, fluconazole injectable 100 mg/50 ml, rifampicine 600 mg en perfusion, sulfadiazine argentique crème, acide fusidique 2% crème, etc.); 70% des prescriptions sont non documentées. La voie injectable est prépondérante (89%). En tout, 227 ordonnances nominatives d'antibiothérapie ont été analysées: la posologie et les contre-indications ont été respectées par rapport à l'autorisation de mise sur le marché. Trois cas d'interactions médicamenteuses ont été relevés (fluconazole-rifampicine, fluconazole-Saccharomyces boulardii, amikacine-vancomycine). Ce constat montre l'importance de l'analyse pharmaceutique des prescriptions des antibiotiques dans un service utilisant des antibiotiques de la réserve hospitalière, donc actifs mais très toxiques. PMID:22396670

  4. Analyse économique de la gestion des déchets solides et du ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    La plupart des villes à croissance rapide en Asie du Sud sont confrontées à une augmentation de l'engorgement et de la contamination de l'eau en raison de la mauvaise gestion des déchets solides. Il est attendu que des événements climatiques extrêmes comme les inondations et la sécheresse compliqueront davantage ...

  5. 243 Caractérisation floristique et analyse des formes de pression ...

    African Journals Online (AJOL)

    Afrique Sciences

    Résumé. L'objectif de cette étude est d'évaluer les ressources biologiques des forêts sacrées en vue de définir des stratégies pour leur maintien. Le SIG a permis de réaliser la carte de végétation de la forêt qui a servi de base pour la collecte des données floristiques et dendrométriques. La classification hiérarchique des ...

  6. Risk analysis related to dangerous materials transport and storage in urban areas; L'integration du risque lie au transport et au stockage des produits chimiques dans la planification urbaine: l'apport des outils d'analyse decisionnelle

    Energy Technology Data Exchange (ETDEWEB)

    Lombard, J; Hubert, P; Pages, P

    1989-12-01

    Risk management in an urban areas not always an easy task and the selection of appropriate prevention measure is often difficult. Consequences of an accident can be multiple (mortality, destruction, pollution, interruption of supplies, economic losses, traffic difficulties), and preventive measures are difficult to compare. The objective of this report is to present different methods applicable for decision making emphasising the criteria for their intercomparison and their limitations. In any case a more sophisticated analysis is needed for risk management in urban areas. Principals of methods needed for decision making are presented. These methods are based on a single criteria (regular constraint), on a few criteria that can be measured (cost-benefit), or a number of criteria at choice. These rather general methods should be adaptable to be applied for specific domain. For risk management the following adaptation are presented: identifying the limit of maximum individual risk (generalisation of regular constraint); adoption of different values of human life as a function of nature of consequences (generalisation of cost-benefit method), application of risk avoidance factors. These different developments predict versions of tools for decision making which can be applicable to risk management in urban areas. [French] La gestion des risques en milieu urbain n'est pas toujours une tache aisee et la selection du moyen de prevention approprie sera souvent difficile. En effet, les consequences d'un accident peuvent etre multiples (mortalite, morbidite, destruction, pollution, interruption de reseaux, pertes economiques, difficultes de circulation...) et les moyens de prevention envisageables pour limiter l'occurrence d'un accident et/ou les consequences associees seront alors difficiles a comparer. Le recours a une methode d'evaluation permettant de quantifier puis de comparer les merites respectifs de ces differents moyens devient aujourd'hui necessaire afin de

  7. Les représentations du VIH, des personnes vivant avec le VIH et des soins dans les manuels en soins infirmiers : une analyse qualitative de contenu

    Directory of Open Access Journals (Sweden)

    Stephany Cator

    2018-03-01

    Full Text Available Depuis la découverte du virus, les manuels en soins infirmiers incluent la notion de VIH/sida pour qu’elle soit transmise dans la formation de premier cycle. Cependant, les écrits dévoilent l’existence d’un écart entre cette formation et les compétences requises pour prodiguer des soins aux personnes vivant avec le VIH. Conscientes des lacunes de la formation initiale en VIH/sida et qui, à ce jour, n’ont pas été explorées dans les manuels, nous avons réalisé une analyse qualitative de contenu de 18 manuels de médecine-chirurgie. Les résultats de cette étude ont dévoilé trois catégories : les représentations du VIH, des personnes vivant avec le VIH et des soins. La première catégorie renvoie à la façon dont on raconte l’histoire du VIH et parle du virus ainsi que la façon dont on décrit la maladie et conceptualise la transmission. La deuxième correspond aux personnes qui sont à risque de contracter le VIH, qui vivent avec le VIH et à la façon dont on les représente. La troisième réfère à la représentation des types de soins, leurs objectifs et les enjeux qui y sont associés.

  8. Experiments on light water lattices with enriched uranium fuel; Analyse des donnees experimentales sur les reseaux a eau legere et uranium enrichi

    Energy Technology Data Exchange (ETDEWEB)

    Audinet, M [Societe des Forges et Ateliers du Creusot, 75 - Paris (France); Lamare, J de [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires; Panossian, J [Societe Alsacienne de Constructions Mecaniques (France)

    1958-07-01

    Experiments a light water lattices with slightly enriched uranium fuel, have been performed at Brookhaven and Bettis Plant Laboratories. The results are studied and compared with simple theories on reactor calculations. By taking into account shadow effects and non Maxwellian neutron spectrum, which are important in this kind of reactors, we have been able to explain the observed results fairly well. We can thus give a constituent set of formulas with which to calculate lattices similar to there we studied. (author) [French] Les resultats d'experiences effectuees aux Laboratoires de Brookbaven et de Bettis Plant, sur des reseaux heterogenes a eau legere et uranium metallique legerement enrichi, sont analyses et confrontes avec les theories simples du calcul de pile. En tenant compte des effets d'interaction et d'echauffement du spectre de neutrons qui sont importants dans ce type de reacteurs, on parvient a rendre compte convenablement des resultats observes. On a ainsi mis au point un formulaire permettant le calcul des reseaux quivpeuvent etre consideres comme assez semblables aux reseaux etudies. (auteur)

  9. Analyses of karyotypes and comparative physical locations of the ...

    African Journals Online (AJOL)

    The frequencies of signal detection of the marker, RG556 and the BAC clone, 44B4, were 8.0 and 41.3% in O. sativa, while 9.0 and 42.3% in O. officinalis, respectively. Based on a comparative RFLP map of a wild rice, O. officinalis and O. sativa, comparative analyses of karyotypes of O. officinalis were demonstrated firstly ...

  10. A method for reducing memory errors in the isotopic analyses of uranium hexafluoride by mass spectrometry; Methode de reduction des erreurs de memoire dans les analyses isotopiques de l'hexafluorure d'uranium par spectrometrie de masse

    Energy Technology Data Exchange (ETDEWEB)

    Bir, R [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1961-07-01

    One of the most serious causes of systematic error in isotopic analyses of uranium from UF{sub 6} is the tendency of this material to become fixed in various ways in the mass spectrometer. As a result the value indicated by the instrument is influenced by the isotopic composition of the substances previously analysed. The resulting error is called a memory error. Making use of an elementary mathematical theory, the various methods used to reduce memory errors are analysed and compared. A new method is then suggested, which reduces the memory errors to an extent where they become negligible over a wide range of {sup 235}U concentration. The method is given in full, together with examples of its application. (author) [French] Une des causes d'erreurs systematiques les plus graves dans les analyses isotopiques d'uranium a partir d'UF{sub 6} est l'aptitude de ce produit a se fixer de diverses manieres dans le spectrometre de masse. Il en resulte une influence de la composition isotopique des produits precedemment analyses sur la valeur indiquee par l'appareil. L'erreur resultante est appelee erreur de memoire. A partir d'une theorie mathematique elementaire, on analyse et on compare les differentes methodes utilisees pour reduire les erreurs de memoire. On suggere ensuite une nouvelle methode qui reduit les erreurs de memoire dans une proportion telle qu'elles deviennent negligeables dans un grand domaine de concentration en {sup 235}U. On donne le mode operatoire complet et des exemples d'application. (auteur)

  11. Comprendre le développement professionnel par l’analyse des discours

    Directory of Open Access Journals (Sweden)

    Sabine Vanhulle

    2011-07-01

    Full Text Available Dans un dispositif consacré au développement professionnel, nos étudiants en enseignement secondaire tiennent un portfolio. Celui-ci se clôture par un récit de trajectoire. Notre recherche réside dans l’analyse de ces récits à partir d’une grille d’indicateurs linguistiques. Ces indicateurs nous informent sur les processus réflexifs et discursifs à l’œuvre dans l’élaboration de savoirs professionnels. Ce premier niveau de description conduit à une méthode de recherche herméneutique. Il s’agit alors de mettre en lumière les préoccupations sous-jacentes à ces processus : systèmes de valeurs, de motivations et d’intentions ; tensions entre les savoirs scientifiques et la confrontation aux réalités vécues dans l’expérience ; constructions identitaires conflictuelles. Nous questionnons les conditions sociales externes et propres au contexte de formation qui influencent la production de ces récits. Nous en dégageons les implications méthodologiques pour l’analyse de discours à visée descriptive et compréhensive. Sur cette base, nous discutons quelques résultats de la recherche.Mots-clés : Portfolio. Savoirs professionnels écrits. Indicateurs de développement. Formation des valeurs. Herméneutique.

  12. Analysis of FFAG accelerators and the evolution of circular accelerators; L'analyse des accelerateurs FFAG et l'evolution des accelerateurs circulaires

    Energy Technology Data Exchange (ETDEWEB)

    Laslett, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires; [Iowa State Univ., U.S. Office of Naval Research, Dept. of Physics and Institute for Atomic Research, Ames (United States)

    1961-07-01

    After rapidly comparing circular machines with the linear accelerator and the reasons for the choice of an annular high energy and very high intensity accelerator, recent problems concerning accelerator theory are discussed, with emphasis on their physical character. The FFAG principle. The limit of the energy of FFAG cyclotron. The setting-up and interpreting of mean energy of focusing terms for a spiral FFAG synchrotron. The limiting amplitude stable near the non-linear resonance 2Q{sub z} = Q{sub r}, as well as the linear coupling resonance of Walkinshaw 2Q{sub z} = Q{sub r}. The crossed-beam accelerator. The 40 MeV electron model of MURA. Two other parts deal with linear and non-linear methods of injection and extraction using a variable disturbance applied to the magnetic field, as well as to collective effects. The interaction of the beam with the accelerating cavities and the walls. The modification of the phase oscillation equation. The influence of the beams' high frequency fields on the Nielsen longitudinal instability. (author) [French] Apres une comparaison rapide des machines circulaires avec l'accelerateur lineaire et une motivation du choix en faveur d'un accelerateur circulaire de haute energie et tres haute intensite, des problemes recents de la theorie des accelerateurs sont discutes, en insistant sur leur contenu physique. Le principe FFAG. La limitation en energie des cyclotrons FFAG. L'etablissement et l'interpretation des termes de la force moyenne de focalisation d'un synchrotron FFAG spirale. L'amplitude de limite stable a proximite de la resonance non-lineaire Q{sub r} = N/3, ainsi que la resonance lineaire de couplage de Walkinshaw 2Q{sub z} = Q{sub r}. L'accelerateur a faisceaux croises. Le modele a electrons de 40 MeV du MURA. Deux autres chapitres sont consacres a des methodes lineaires et non-lineaires d'injection et d'extraction a l'aide d'une perturbation variable appliquee au champ magnetique, ainsi qu'aux effets collectifs. L

  13. Comparison of BEACON and COMPARE reactor cavity subcompartment analyses

    International Nuclear Information System (INIS)

    Burkett, M.W.; Idar, E.S.; Gido, R.G.; Lime, J.F.; Koestel, A.

    1984-04-01

    In this study, a more advanced best-estimate containment code, BEACON-MOD3A, was ued to calculate force and moment loads resulting from a high-energy blowdown for two reactor cavity geometries previously analyzed with the licensing computer code COMPARE-MOD1A. The BEACON force and moment loads were compared with the COMPARE results to determine the safety margins provided by the COMPARE code. The forces and moments calculated by the codes were found to be different, although not in any consistent manner, for the two reactor cavity geometries studied. Therefore, generic summary statements regarding margins cannot be made because of the effects of the detailed physical configuration. However, differences in the BEACON and COMPARE calculated forces and moments can be attributed to differences in the modeling assumptions used in the codes and the analyses

  14. Analyse situationnelle des politiques de lutte contre l'usage nocif de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    le marketing et la promotion des boissons alcoolisées. L'Université du Cap accueillera le projet-cadre, en assurera la surveillance sur le plan de l'éthique et offrira la formation et le soutien scientifique. Elle aidera à faire la synthèse des données recueillies dans les différents pays et appuiera la rédaction d'un article portant ...

  15. Analyse du financement de la santé et des avantages en Ouganda ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le nouveau site Web facilitera l'enregistrement des événements démographiques afin d'améliorer l'accès aux services pour tous. Le nouveau site Web et la nouvelle bibliothèque de ressources aideront à améliorer les systèmes d'information et d'enregistrement des faits d'état civil dans les pays en développement.

  16. analyse de la variabilite des rendements du riz selon les varietes et ...

    African Journals Online (AJOL)

    ACSS

    15 févr. 2018 ... objectif, l'étude s'est basée sur une phase d'enquête basée sur un questionnaire intégré dans un Smartphone, et une autre phase d'observation, basée sur la mise en place des placettes et sous-placettes dans les champs des producteurs afin de recueillir les informations sur les pratiques culturales du riz ...

  17. Quantitative analysis of fission products by {gamma} spectrography; Analyse quantitative des produits de fission par spectrographie {gamma}

    Energy Technology Data Exchange (ETDEWEB)

    Malet, G

    1962-07-01

    The activity of the fission products present in treated solutions of irradiated fuels is given as a function of the time of cooling and of the irradiation time. The variation of the ratio ({sup 144}Ce + {sup 144}Pr activity/{sup 137}Cs activity) as a function of these same parameters is also given. From these results a method is deduced giving the 'age' of the solution analyzed. By {gamma}-scintillation spectrography it was possible to estimate the following elements individually: {sup 141}Ce, {sup 144}Ce + {sup 144}Pr, {sup 103}Ru, {sup 106}Ru + {sup 106}Rh, {sup 137}Cs, {sup 95}Zr + {sup 95}Nb. Yield curves are given for the case of a single emitter. Of the various existing methods, that of the least squares was used for the quantitative analysis of the afore-mentioned fission products. The accuracy attained varies from 3 to 10%. (author) [French] L'activite des produits de fission presents dans les solutions de traitement de combustibles irradies est donnee en fonction du temps de refroidissement et du temps d'irradiation. On etudie de plus la variation du rapport Activite du {sup 144}Ce + {sup 144}Pr /Activite du {sup 137}Cs en fonction de ces memes parametres. De ces resultats, on deduit une methode donnant l'age de la solution analysee. La spectrographie {gamma} a scintillation a permis le dosage individuel des produits suivants: {sup 141}Ce, {sup 144}Ce + {sup 144}Pr, {sup 103}Ru, {sup 106}Ru + {sup 106}Rh, {sup 137}Cs, {sup 95}Zr + {sup 95}Nb. Des courbes de rendement sont donnees dans le cas d'un emetteur unique. Des differentes methodes existantes, la methode des moindres carres a ete employee pour l'analyse quantitative des produits de fission precites. La precision obtenue varie entre 3 et 10 pour cent. (auteur)

  18. Accounting for rate variation among lineages in comparative demographic analyses

    Science.gov (United States)

    Hope, Andrew G.; Ho, Simon Y. W.; Malaney, Jason L.; Cook, Joseph A.; Talbot, Sandra L.

    2014-01-01

    Genetic analyses of contemporary populations can be used to estimate the demographic histories of species within an ecological community. Comparison of these demographic histories can shed light on community responses to past climatic events. However, species experience different rates of molecular evolution, and this presents a major obstacle to comparative demographic analyses. We address this problem by using a Bayesian relaxed-clock method to estimate the relative evolutionary rates of 22 small mammal taxa distributed across northwestern North America. We found that estimates of the relative molecular substitution rate for each taxon were consistent across the range of sampling schemes that we compared. Using three different reference rates, we rescaled the relative rates so that they could be used to estimate absolute evolutionary timescales. Accounting for rate variation among taxa led to temporal shifts in our skyline-plot estimates of demographic history, highlighting both uniform and idiosyncratic evolutionary responses to directional climate trends for distinct ecological subsets of the small mammal community. Our approach can be used in evolutionary analyses of populations from multiple species, including comparative demographic studies.

  19. Analysis and separation of boron isotopes; Analyse et separation des isotopes du bore

    Energy Technology Data Exchange (ETDEWEB)

    Perie, M [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1966-11-01

    operatoire pour l'analyse de traces de-bore,par dilution isotopique. Par ailleurs, les besoins en bore-10 de l'industrie nucleaire justifient la mise au point de procedes de separation des isotopes du bore. Un effet isotopique notable a ete mis en evidence dans la reaction d'echange chimique entre le borate de methyle et un sel borique en solution. Dans le cas de l'echange borate de methyle - borate de sodium, le facteur de separation elementaire {alpha}: {alpha}=(({sup 11}B/{sup 10}B)vap.)/(({sup 11}B/{sup 10}B)liq.)=1.03{sub 3}. Cet effet elementaire eleve a ete multiplie dans une colonne de distillation dans laquelle le probleme de la regeneration des reactifs a ete resolu. Une variante de ce procede a ete etudiee, en remplacant le borate alcalin par un borate de base volatile; ici la diethylamine ({alpha}=1,02{sub 5} en milieu hydromethanolique a 2,2 pour cent d'eau). (auteur)

  20. Comparative Transcriptional Analyses of Francisella tularensis and Francisella novicida.

    Directory of Open Access Journals (Sweden)

    Siva T Sarva

    Full Text Available Francisella tularensis is composed of a number of subspecies with varied geographic distribution, host ranges, and virulence. In view of these marked differences, comparative functional genomics may elucidate some of the molecular mechanism(s behind these differences. In this study a shared probe microarray was designed that could be used to compare the transcriptomes of Francisella tularensis subsp. tularensis Schu S4 (Ftt, Francisella tularensis subsp. holarctica OR960246 (Fth, Francisella tularensis subsp. holarctica LVS (LVS, and Francisella novicida U112 (Fn. To gain insight into expression differences that may be related to the differences in virulence of these subspecies, transcriptomes were measured from each strain grown in vitro under identical conditions, utilizing a shared probe microarray. The human avirulent Fn strain exhibited high levels of transcription of genes involved in general metabolism, which are pseudogenes in the human virulent Ftt and Fth strains, consistent with the process of genome decay in the virulent strains. Genes encoding an efflux system (emrA2 cluster of genes, siderophore (fsl operon, acid phosphatase, LPS synthesis, polyamine synthesis, and citrulline ureidase were all highly expressed in Ftt when compared to Fn, suggesting that some of these may contribute to the relative high virulence of Ftt. Genes expressed at a higher level in Ftt when compared to the relatively less virulent Fth included genes encoding isochorismatases, cholylglycine hydrolase, polyamine synthesis, citrulline ureidase, Type IV pilus subunit, and the Francisella Pathogenicity Island protein PdpD. Fth and LVS had very few expression differences, consistent with the derivation of LVS from Fth. This study demonstrated that a shared probe microarray designed to detect transcripts in multiple species/subspecies of Francisella enabled comparative transcriptional analyses that may highlight critical differences that underlie the relative

  1. Analyses of functional brain connectivity; Untersuchungen zur funktionellen Konnektivitaet des Gehirns

    Energy Technology Data Exchange (ETDEWEB)

    Stephan, K.E.

    2003-03-01

    This dissertation includes two independent studies that investigate two complementary aspects of functional connectivity in the Macaque and the human brain. In the first study, a computational meta-analysis of published electrophysiological data on context-independent functional brain connectivity was conducted by means of three independent methods. The second study investigated the effects of the atypical antipsychotic substance olanzapine on the functional connectivity of the cerebellum during a simple motor task (self-paced finger tapping). Six schizophrenic patients and six control subjects matched for age and sex were investigated by functional magnetic resonance imaging (fMRI) twice. This study provided the first experimental data on the effects of atypical antipsychotic agents on functional brain connectivity and demonstrated pronounced olanzapine-dependent changes of functional couplings between cerebellum, thalamus, and prefrontal cortex. (orig.) [German] In der hier vorgelegten Arbeit werden zwei komplementaere Aspekte der funktionellen Konnektivitaet - im Gehirn des Makaken und Menschen anhand zweier separater Studien untersucht. In der ersten Studie wurde mittels dreier unabhaengiger Methoden eine Metaanalyse publizierter elektrophysiologischer Daten zur kontextunabhaengigen funktionellen Konnektivitaet des Makakenkortex durchgefuehrt. Diese Studie erbrachte damit zum ersten Mal den Nachweis einer funktionellen Small World-Netzwerkstruktur des Primatenkortex. In der zweiten Studie wurde der Effekt des atypischen Neuroleptikums Olanzapin auf die funktionelle Konnektivitaet des Zerebellums im Kontext einer einfachen motorischen Aufgabe (selbstgesteuertes Fingertrapping) untersucht. Sechs schizophrene Patienten, die Neuroleptika-naiv bzw. -entwoehnt waren, sowie sechs alters- und geschlechtsentprechende Kontrollprobanden wurden im Abstand von jeweils drei Wochen mit funktioneller Magnetresonanztomografie (fMRT) untersucht. Diese Studie lieferte die ersten

  2. Une géographie de la coopération universitaire France-Brésil, analyse des accords Capes-Cofecub

    Directory of Open Access Journals (Sweden)

    Hervé Théry

    2011-04-01

    Full Text Available L’analyse et la cartographie des 750 accords de coopération universitaire entre la France et le Brésil fait apparaître, au-delà de l’effet évident des hiérarchies urbaines (les villes les plus peuplées sont aussi les grands centres universitaires, des spécialisations qui renvoient à des traditions locales et la résultante des réseaux des équipes candidates.The analysis and mapping of the 750 agreements for academic cooperation between France and Brazil shows, beyond the obvious effect of urban hierarchies (the most populous cities are also the major academic centers, specializations wich refer to local traditions and the result of networking made by the candidate teams.

  3. Amélioration des performances environnementales des pratiques viticoles et analyse des risques pour la qualité du raisin : étape vers l’écoqualiconception©

    Directory of Open Access Journals (Sweden)

    Beauchet Sandra

    2017-01-01

    Full Text Available L’évolution des itinéraires techniques viticoles (ITKv vers un plus grand respect de l’environnement passe par une évaluation de leurs performances environnementales. Dans un contexte de gestion durable, plusieurs autres facteurs sont à prendre en compte, notamment le risque de modification de la qualité des raisins issus de ces ITKv. Les résultats d’évaluation environnementale par la méthode d’Analyse du Cycle de Vie (ACV ainsi que l’évaluation de la qualité du raisin s’appuient sur beaucoup données. Ce travail montre l’intérêt d’une méthode d’évaluation multicritère conjointe « environnement et qualité », dans le processus de changement de pratiques pour une amélioration des performances. Les résultats obtenus sur 5 ITKv montrent des différences de notes entre les 2 millésimes étudiés et des pratiques ont été identifiées pour leurs forts impacts sur les résultats ACV. Des propositions théoriques de changement de pratiques sont testées sur l’un des ITKv. Ces propositions améliorent les notes environnementales finales de +0,15 points à +0,77 points (/10 quand elles sont mises en œuvre séparément et +2,29 points (/10 en étant combinées. Un modèle explicatif de la qualité du raisin permet de vérifier que les nouvelles pratiques ne peuvent potentiellement pas altérer la qualité du raisin. La méthode d’évaluation conjointe CONTRA-QUALENVIC adaptée à la viticulture montre ici qu’elle peut être une aide à l’amélioration des ITKv.

  4. Quantitative analysis of textures produced in a hot-extruded zirconium plate; Analyse quantitative des textures developpees dans une plaque de zirconium filee a chaud

    Energy Technology Data Exchange (ETDEWEB)

    Couterne, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires. Institut national des sciences et techniques nucleaires, laboratoire de metallurgie

    1967-01-01

    etudiees par la methode de Schulz en se referant a un etalon isotrope. Ces textures ont. ete determinees soit parallelement au plan de la plaque, soit parallelement au plan des rives. Tous les resultats sont analyses dans une discussion finale qui permet, en particulier au voisinage des aretes de la plaque, de montrer que certaines composantes des textures observees clans les deux series d'enregistrements, sont en fait l'expression de la meme texture vue sous deux angles differents. D'autre part. it est montre que le zirconium ainsi mis en forme comporte des textures d'ecrouissage et de recristallisation posterieure a l'ecrouissage precedent. En schematisant l'ensemble des textures determinees, on observe trois textures dont deux deja signalees dans la bibliographie et comparable a celles des produits lamines: ces textures sont telles que les plans. (0001 presentent des inclinaisons respectives de 36 deg C et 60 deg C par rapport a un plan tangent a la courbe (enveloppe des vitesses d'ecoulement transverse) resulant de la geometrie du filage considere; la troisieme texture est definie par le fait que le plan (0001) est orthogonal aux surfaces exterieures de la plaque. La direction de filage associee a ces plans et commune aux trois textures est du type <1010>. Des essais dilatometriques ont ete effectues sur des echantillons preleves dans le sens du filage et clans le sens transverse. Ces essais mettent en evidence l'anisotropie dilatometrique du zirconium ainsi qu'un changement de pente de la courbe ({alpha}{sub v}){sub a} en fonction de la temperature a partir de 400 drg C, pouvant etre explique par la variation de la configuration electronique du metal a partir de cette temperature. (auteur)

  5. Quantitative analysis of textures produced in a hot-extruded zirconium plate; Analyse quantitative des textures developpees dans une plaque de zirconium filee a chaud

    Energy Technology Data Exchange (ETDEWEB)

    Couterne, J. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires. Institut national des sciences et techniques nucleaires, laboratoire de metallurgie

    1967-01-01

    ete etudiees par la methode de Schulz en se referant a un etalon isotrope. Ces textures ont. ete determinees soit parallelement au plan de la plaque, soit parallelement au plan des rives. Tous les resultats sont analyses dans une discussion finale qui permet, en particulier au voisinage des aretes de la plaque, de montrer que certaines composantes des textures observees clans les deux series d'enregistrements, sont en fait l'expression de la meme texture vue sous deux angles differents. D'autre part. it est montre que le zirconium ainsi mis en forme comporte des textures d'ecrouissage et de recristallisation posterieure a l'ecrouissage precedent. En schematisant l'ensemble des textures determinees, on observe trois textures dont deux deja signalees dans la bibliographie et comparable a celles des produits lamines: ces textures sont telles que les plans. (0001 presentent des inclinaisons respectives de 36 deg C et 60 deg C par rapport a un plan tangent a la courbe (enveloppe des vitesses d'ecoulement transverse) resulant de la geometrie du filage considere; la troisieme texture est definie par le fait que le plan (0001) est orthogonal aux surfaces exterieures de la plaque. La direction de filage associee a ces plans et commune aux trois textures est du type <1010>. Des essais dilatometriques ont ete effectues sur des echantillons preleves dans le sens du filage et clans le sens transverse. Ces essais mettent en evidence l'anisotropie dilatometrique du zirconium ainsi qu'un changement de pente de la courbe ({alpha}{sub v}){sub a} en fonction de la temperature a partir de 400 drg C, pouvant etre explique par la variation de la configuration electronique du metal a partir de cette temperature. (auteur)

  6. Creating global comparative analyses of tectonic rifts, monogenetic volcanism and inverted relief

    Science.gov (United States)

    van Wyk de Vries, Benjamin

    2016-04-01

    I have been all around the world, and to other planets and have travelled from the present to the Archaean and back to seek out the most significant tectonic rifts, monogenetic volcanoes and examples of inverted relief. I have done this to provide a broad foundation of the comparative analysis for the Chaîne des Puys - Limagne fault nomination to UNESCO world Heritage. This would have been an impossible task, if not for the cooperation of the scientific community and for Google Earth, Google Maps and academic search engines. In preparing global comparisons of geological features, these quite recently developed tools provide a powerful way to find and describe geological features. The ability to do scientific crowd sourcing, rapidly discussing with colleagues about features, allows large numbers of areas to be checked and the open GIS tools (such as Google Earth) allow a standardised description. Search engines also allow the literature on areas to be checked and compared. I will present a comparative study of rifts of the world, monogenetic volcanic field and inverted relief, integrated to analyse the full geological system represented by the Chaîne des Puys - Limagne fault. The analysis confirms that the site is an exceptional example of the first steps of continental drift in a mountain rift setting, and that this is necessarily seen through the combined landscape of tectonic, volcanic and geomorphic features. The analysis goes further to deepen the understanding of geological systems and stresses the need for more study on geological heritage using such a global and broad systems approach.

  7. Analyse des variables cachées influant sur les difficultés et ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Bill

    1 mars 2012 ... il peut s'agir aussi d'une politique organisationnelle qui incite les employés et les .... une importance stratégique face aux aspirations à long terme des .... le plus important pour assurer la réussite d'un PPP consiste à recruter.

  8. 149 Résumé Notre article se propose d'analyser le travail des ...

    African Journals Online (AJOL)

    8 juil. 2008 ... ... la dynamique de l'économie informelle, c'est le rapport à la loi qui est décisif… » ... qui très souvent, pour ne pas dire systématiquement, attire le con- sensus chez ceux qui .... des secteurs modernes…» (A.Invernizzi.

  9. Etude comparative de la flore aux abords des cours d'eau dans les ...

    African Journals Online (AJOL)

    Etude comparative de la flore aux abords des cours d'eau dans les zones hypo et hyper endémiques d'ulcère de Buruli en Côte d'Ivoire. C. Cisse Boni, E. Ehouman, D. Soro, M.W. Kone, A. Bakayoko, F. Dembele, K. Bauthire, M Dosso ...

  10. Analyse spatialisée pour l'aide à la planification des projets de méthanisation collective

    Directory of Open Access Journals (Sweden)

    BIOTEAU, Thierry

    2013-10-01

    Full Text Available Le développement de la méthanisation dépend de plusieurs facteurs. Il s’agit, entre autres, des ressources disponibles, de leur proximité, des caractéristiques de l’économie locale et de leur impact sur le processus de décision. Ces éléments doivent nécessairement être pris en compte pour une mise en place pertinente de centres de production de biogaz. L’analyse menée en Pays de Fougères envisage tous ces points et permet de dégager différents scenarii.

  11. Analysis of electronic circuits using digital computers; L'analyse des circuits electroniques par les calculateurs numeriques

    Energy Technology Data Exchange (ETDEWEB)

    Tapu, C [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1968-07-01

    Various programmes have been proposed for studying electronic circuits with the help of computers. It is shown here how it possible to use the programme ECAP, developed by I.B.M., for studying the behaviour of an operational amplifier from different point of view: direct current, alternating current and transient state analysis, optimisation of the gain in open loop, study of the reliability. (author) [French] Differents programmes ont ete proposes pour l'etude des circuits electroniques a l'aide des calculateurs. On montre comment on peut utiliser le programme ECAP, mis au point par I. B. M., pour etudier le comportement d'un amplificateur operationnel, a differents points de vue: analyse en courant continu, courant alternatif et regime transitoire, optimalisation du gain en boucle ouverte, etude de la fiabilite. (auteur)

  12. Exploration des variantes d'artefacts logiciels pour une analyse et une migration vers des lignes de produits

    OpenAIRE

    Martinez , Jabier

    2016-01-01

    Software Product Lines (SPLs) enable the derivation of a family of products based on variability management techniques. Inspired by the manufacturing industry, SPLs use feature configurations to satisfy different customer needs, along with reusable assets to allow systematic reuse. Capitalizing on existing variants by extracting the common and varying elements is referred to as extractive approaches for SPL adoption. Feature identification is needed to analyse the domain variability. Also, to...

  13. Centrales au gaz et Energies renouvelables: comparer des pommes avec des pommes

    Energy Technology Data Exchange (ETDEWEB)

    Bolinger, Mark; Wiser, Ryan; Golove, William

    2003-10-20

    The fundamental conclusion that we draw from this analysis is that one should not to base itself blindly on forecasts prices of natural gas when one compare contracts at price fixes with producers of renewable energy with contracts at variable prices with promoters power stations with gas. Indeed, forecasts of the prices of gas do not succeed not to enter the associated costs with the covering of the risk, that they are connected to the negative pressure against the cover, with the CAPM, with costs of transaction or with unspecified combination of three. Thus, insofar as price stability to length term is developed, better way of comparing the two choices would be to have recourse to the data on the prices in the long term natural gas, and not with forecasts of the prices. During three last years at least, the use of these prices in the long term would have besides license to correct a methodological error who, obviously, seem to have supported unduly, and of relatively important way, power stations with natural gas compared to their competitors of renewable energies.

  14. Relever le défi d'analyse statistique dans des études en ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le CRDI et Cancer Research UK lancent une nouvelle initiative contre le tabagisme. Le CRDI et Cancer Research UK ont le plaisir d'annoncer le lancement d'une nouvelle initiative d'une durée de cinq ans visant la prévention des maladies liées au tabagisme. Voir davantageLe CRDI et Cancer Research UK lancent une ...

  15. 47 Analyse des images satellitales radar RSO-ERS et optique ETM+ ...

    African Journals Online (AJOL)

    PR BOKO

    Des cartes à plus grande échelle au 1/100 000 ont aussi dressées, dans le cadre du projet de coopération géologique ivoiro- allemenande [5, 6]. ..... [13] - SOCIETE POUR LE DEVELOPPEMENT MINIER IVOIRIEN (SODEMI), "Carte photo-géologique à 1/200 000, feuille de Tienko-Odienné", (1978). [14] - K. POTHIN et A.

  16. Utilisation des analyses multivariées dans la caractérisation de la ...

    African Journals Online (AJOL)

    SARAH

    30 juin 2013 ... sélectivité des filets de pêche dépend de la nature du filet, de la maille, de la hauteur de chute, du rapport d'armement, de la saison et de la longueur totale du poisson et que d'autre part les FMDS à grandes mailles. (56 à 60mm) sont les plus sélectifs de tous les engins utilisés pour la capture du mulet ...

  17. Analyse empirique des facteurs explicatifs de la décision d'activation des dépenses de recherche et développement : Cas des entreprises françaises

    OpenAIRE

    Charfi-Laadhar , Souha

    2006-01-01

    International audience; L'objet de cette étude est d'analyser les facteurs explicatifs du choix de l'activation, comme mode de comptabilisation des dépenses de recherche et développement (R&D), pour un échantillon d'entreprises françaises oeuvrant dans des secteurs industriels de haute technologie. Le modèle « logit » utilisé dans cette étude met en relation la décision d'activer les dépenses de R&D avec certains déterminants bien documentés dans la littérature en comptabilité (la taille de l...

  18. Les théories des mouvements sociaux et la dialectique des niveaux : un cadre d’analyse pour l’étude des évolutions d’Al-Qaïda au Maghreb islamique

    OpenAIRE

    Adib Bencherif

    2013-01-01

    Les théories des mouvements sociaux sont de plus en plus utilisées pour étudier les groupes terroristes. Elles comportent différents niveaux d’analyse: les niveaux macro-analytique, méso-analytique et micro-analytique. Le présent article tente d’adapter ce corpus théorique à l’étude du groupe jihadiste Al-Qaïda au Maghreb islamique (AQMI). En effet, au cours des dernières années, AQMI ne s’est pas développé au Maghreb alors que ses activités ont augmenté exponentiellement dans la région sahél...

  19. Formalisation des bases méthodologiques et conceptuelles d'une analyse spatiale des accidents de la route

    Directory of Open Access Journals (Sweden)

    Florence Huguenin Richard

    1999-06-01

    Full Text Available Cet article pose les bases méthodologiques et conceptuelles d’une analyse spatiale du risque routier. L’étude de ce phénomène requiert une masse importante de données qui décrivent différentes dimensions de l’accident et qui peuvent être gérées dans un système d’information géographique. Elle demande aussi une réflexion méthodologique sur la cartographie du risque, les échelles d’observation, l’agrégation de données qualitatives et quantitatives, l’utilisation de méthodes statistiques adaptées au risque routier et l'intégration de l’espace comme facteur d’insécurité.

  20. Analyse géochimique des hydrocarbures légers par thermovaporisation Geochemical Analysis of Light Hydrocarbons by Thermovaporization

    OpenAIRE

    Jonathan D.; L'hote G.; Du Rouchet J.

    2006-01-01

    Le procédé de thermovaporisation est utilisé pour l'extraction et l'analyse des hydrocarbures à point d'ébullition situé à l'intérieur de l'intervalle correspondant aux alcanes C6 à C15; il s'applique également aux roches et aux huiles. La mise en ceuvre est simple et rapide, ce qui rend cette technique utilisable dans certains laboratoires de chantiers d'exploration. Les chromatogrammes de vapeurs montrent une succession de pics, chaque pic correspondant théoriquement à un composant défini, ...

  1. Efficacité comparée des insecticides de natures différentes dans la ...

    African Journals Online (AJOL)

    SARAH

    gestion des insectes ravageurs du niébé au Centre du Bénin. 7695. Efficacité comparée .... basées sur la lutte biologique pour le contrôle de M. vitrata. Ces méthodes ..... Dynamique de la population de M. vitrata : La figure 1 illustre l'effet des ...

  2. Du type au stéréotype : analyse des modalités d’insertion des stéréotypes des physiologies dans Bouvard et Pécuchet

    Directory of Open Access Journals (Sweden)

    Vincent Stohler

    2011-01-01

    Full Text Available Cette analyse a pour but d’exposer la manière dont Flaubert récupère les stéréotypes présents dans les physiologies, genre littéraire à la mode dans la première moitié du XIXe siècle, en définissant leurs différentes modalités d’insertion dans Bouvard et Pécuchet. Après s’être interrogée sur le statut particulier des physiologies, l’étude montre que les différents types qu’elles mettent en scène, et plus particulièrement celui du « bourgeois », fournissent à Flaubert un matériel discursif stéréotypé qui lui sert de base de composition à l’ensemble de son texte : composition des personnages (traits physiques, caractériels, axiologiques, etc., composition structurelle du roman, etc. La démonstration attire ainsi l’attention sur ce qui paraît être l’une des lignes de force de l’écriture flaubertienne : l’amenuisement au sein de l’espace romanesque du langage de l’auteur au profit d’un langage stéréotypé, venu d’ailleurs.

  3. Analyse géographique et modélisation des dynamiques d’urbanisation à La Réunion

    Directory of Open Access Journals (Sweden)

    Pascal Thinon

    2007-07-01

    Full Text Available Cet article propose un prototype de modèle d’interprétation des dynamiques urbaines sur l’Ile de la Réunion. En entrée, le modèle combine un ensemble de champs géographiques jouant en faveur ou en défaveur de l’urbanisation ; en sortie, il indique une propension à l’urbanisation de chaque lieu. Il est conçu de manière à permettre une analyse exploratoire de ces dynamiques selon une approche heuristique. Les premiers résultats ont permis d’obtenir, sur l’ensemble de l’île, une carte de la propension à l’urbanisation, jugée satisfaisante eu égard aux dynamiques observées entre 1989 et 2002 ; un premier scénario d’évolution, concernant les espaces de savanes à l’ouest de l’île, est également proposé. Les premiers travaux sur ce modèle, encore à un stade préliminaire, sont encourageants mais soulèvent de nombreuses questions concernant notamment le calibrage des facteurs et leur rôle respectif, l’intégration de nouveaux champs comme le voisinage, l’analyse des résidus, la mesure de la qualité du modèle ou bien encore la mobilisation de ce type de modèle comme outil d’accompagnement de projets de territoires.

  4. Application des ondelettes à l'analyse de texture et à l'inspection de surface industrielle

    Science.gov (United States)

    Wolf, D.; Husson, R.

    1993-11-01

    This paper presents a method of texture analysis based on multiresolution wavelets analysis. We discuss the problem of theoretical and experimental choice of the wavelet. Statistical modelling of wavelet images is treated and it results in considering statistical distribution to be a generalized Gaussian law. An algorithm for texture classification is developed with respect of the variances of different wavelet images. An industrial application of this algorithm illustrates its quality and proves its aptitude for automation of certain tasks in industrial control. Nous présentons une méthode d'analyse de texture fondée sur l'analyse multirésolution par ondelettes. Nous discutons du problème du choix théorique et expérimental de l'ondelette. Le problème de la modélisation statistique des images d'ondelettes est traité et aboutit à considérer la distribution statistique comme une loi de Gauss généralisée. Un algorithme de classification de texture est construit à l'aide de la variance des différentes images d'ondelettes. Enfin, une application industrielle de cet algorithme illustre ses qualités et démontre son aptitude à l'automatisation de certaines tâches de contrôle industriel.

  5. Applicability of ICRP principles for safety analysis of radioactive waste geological storage; Etude de l'applicabilite des principes de la CIPR a l'analyse de surete du stockage geologique des dechets radioactifs

    Energy Technology Data Exchange (ETDEWEB)

    Lombard, J; Hubert, P; Pages, P

    1987-07-01

    modalites de stockage) doit etre determine par un processus comparatif visant a selectionner le niveau conduisant au meilleur compromis entre es depenses de protection et les risques residuels. Ces recommandations, particulierement Ia seconde, s'ecartent des principes des analyses de surete suivis jusqu'a present en France et a l'etranger; cette etude envisage les avantages et inconvenients potentiels lies a l'introduction de ce second principe. Dans ce but on se base sur differentes analyses realisees au niveau international integrant partiellement au moms ces principes. II ressort de cet examen que ces principes sont applicables mais que leur mise en oeuvre necessite une reorientation de modeles d'evaluation en particulier pour s'affranchir d'hypotheses trop conservatrices. Cette mise en oeuvre necessite par ailleurs davantage d'informations que dans le cas d'une approche deterministe de Ia surete puisqu'il faut estimer les consequences et les probabilites de I'ensemble des evenements possibles et ce pour es diverses modalites de stockage que l'on se propose de comparer. L'integration d'evaluation de ce type est cependant plus riche d'enseignements et constitue de ce fait une aide a Ia decision qui peut etre feconde. On peut enfin souligner que cette approche permet un meilleur dialogue entre les differentes instances decisionnelles et plus generalement entre les acteurs du debat, dans Ia mesure ou elle apporte un langage de discussion commun. On notera d'ailleurs que ce souci de clarification s'exprime quelle que soit I'optique de surete adopte (deterministe ou probabiliste), comme en temoignent les interrogations sur le sens du 'scenario central' de I'etude KBS. Par ailleurs, ii semble que ces principes seront vraisemblablement suivis au plan international afin d'uniformiser en outre les modes de gestion de Ia radioprotection dans ses diff?rentes composantes. (author)

  6. The application of {beta}-ray excitation fluorescence to the measurement of the thickness of deposits and to analysis; Applications de la fluorescence excitee au moyen des rayons {beta} a la mesure des epaisseurs des depots et a l'analyse

    Energy Technology Data Exchange (ETDEWEB)

    Martinelli, P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires; Seibel, G [Institut de Recherches de la Siderurgie Francaise (IRSID), 78 - Saint-Germain-en-Laye (France)

    1961-07-01

    Principles of the method are first outlined and the instrumentation used is described. The different types of radiation detectors are subject of a detailed study. As a source of {beta}-radiation {sup 90}(Sr + Y) was used as well as {sup 147}Pm. Great care was taken to eliminate back-diffused electrons by deflection by a strong permanent magnet. The method was applied to the measurement of the thickness of deposits of Cr, Zn, Sn, Cd and Cu on iron as well as Zn, Cr, Ag and Au on copper and the results obtained are discussed. An attempt was made, to use {beta}-X-ray fluorescence for the analysis of minerals, iron ore and glass and for routine control of Si-Mn, Si-Ca, Fe-Mn and Fe-W. Finally the method of {beta}-X-ray fluorescence is compared with normal-X-ray fluorescence and possibilities of further development are cited. (author) [French] Les principes de la methode et l'instrumentation utilisee sont presentes. On decrit en particulier les detecteurs de rayonnement utilises. Comme source de rayonnement on utilise {sup 90}(Sr + Y) et {sup 147}Pm. Pour eliminer les electrons retrodiffuses on utilise un aimant permanent place sur le trajet du faisceau. La methode est appliquee a la mesure des epaisseurs des depots metalliques tels que le Cr, Zn, Sn, Cd et Cu sur fer et le Zn, Cr, Ag et Au sur cuivre. D'autre part, la fluorescence {beta}-X etait utilisee pour l'analyse des minerais et des verres et pour le controle des alliages Fe-Mn, Fe-W, Si-Mn, Si-Ca. Enfin, on passe a une comparaison entre la fluorescence {beta}-X et la fluorescence X normale et on discute les possibilites d'un developpement futur. (auteur)

  7. Culture du bambou : diversification des moyens de subsistance des ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Culture du bambou : diversification des moyens de subsistance des petits producteurs de tabac du sud de la province de Nyanza, au Kenya - phase II. Au cours de la première phase du projet (projet no 103765), les chercheurs ont effectué une analyse de marché pour le bambou et les produits du bambou, comparé les ...

  8. Analyse des propriétés hydrodynamiques des aquifères fissurés de la région de San-Pedro (Sud-Ouest de la Côte d’Ivoire

    Directory of Open Access Journals (Sweden)

    De-Lasme, O. Z.

    2012-12-01

    Full Text Available San-Pedro area is localized in south-western Côte d’Ivoire and covers a surface of 6912 km2. Wa t e r resources exploited in this area are constituted of surface waters and groundwater of weathered and fissured aquifers. The aims of this study are to analyze hydrodynamic properties of fissured aquifers of San-Pedro on statistical and geostatistical viewpoints for a better knowledge and management of groundwater resources. Data base includes 110 drillings tapping fissured aquifers. Transmissivity was calculated by interpreting of pumping tests with classical methods. Specific capacity was calculated at the end of the third step for all drillings after correction of drawdowns. Transmissivity and specific capacity values oscillate between 1,27.10-6 and 8,59.10-4 m2.s-1 and between 1,09.10-2 m2.h-1 et 13,2 m2.h-1, respectively. These two parameters span three orders of magnitude showing the strong heterogeneity of the medium. An empirical relationship was established between transmissivity and specific capacity of San-Pedro area. This relationship can be used to determine transmissivity in the sectors where this data is lacking. Variogram of transmissivity is characterized by a double structuring. Transmissivity assessment by kriging is satisfactory, observed and estimated values are comparable. The findings obtained in this study lead to a better understanding of hydrogeological properties of south-western Côte d’Ivoire.

    [fr] La région de San-Pedro est localisée dans le sud-ouest de la Côte d’Ivoire et couvre une superficie de 6912 km2. Les ressources en eau exploitées dans cette région sont constituées des eaux de surface et des eaux souterraines des aquifères des altérites et de fissures du socle précambrien. La présente étude a pour objectif d’analyser les propriétés hydrodynamiques des aquif

  9. Etude comparative de la cinétique de la réaction d’hydratation des bétons autoplaçants et des bétons vibrés

    Directory of Open Access Journals (Sweden)

    Ahmed Gargouri

    2014-04-01

    En effet, la nature exothermique de la réaction chimique du ciment peut induire des déformations de dilatation et de contraction. Par ailleurs, la dépression capillaire crée par la consommation d’eau due à l’hydratation du ciment entraine un retrait de dessiccation. Ces déformations peuvent entrainer des micros fissurations pouvant affecter la durabilité de l’ouvrage à long terme surtout pour les ouvrages épais. D’où l’importance d’étudier la cinétique d’hydratation de ses bétons non conventionnels et de les comparer à celle des bétons vibrés traditionnels. L’évolution de la température adiabatique ainsi que la variation en fonction du temps du degré d’hydratation sont déterminées pour le béton autoplaçant et le béton vibré. L’analyse des résultats expérimentaux obtenus montre que le changement de composition modifie considérablement la cinétique de la réaction d’hydratation.

  10. Apport de l'analyse des réseaux sociaux à l'étude des communautés d'apprentissage en ligne Using social network analysis for the study of online learning communities

    Directory of Open Access Journals (Sweden)

    Cédric Sarré

    2012-09-01

    Full Text Available S'il est vrai que de nombreuses recherches ont porté, ces vingt dernières années, sur l'apport de la communication médiatisée par ordinateur (CMO à l'acquisition des langues secondes (L2, peu de travaux se sont intéressés à ce jour à la CMO à base orale (audioconférence et visioconférence et à ses différences et similitudes avec la CMO à base écrite. Cet article se propose d'examiner et de comparer les interactions entre apprenants générées lors de la réalisation de tâches collaboratives en anglais L2 selon trois modes de CMO : le clavardage, la visioconférence et le forum électronique. Les tâches collaboratives ont été proposées aux apprenants dans le cadre du dispositif hybride English for biologists dont l'objectif principal était de favoriser le développement de leur compétence interactionnelle en L2. L'analyse sociométrique des échanges nous permet de mettre en évidence l'influence du mode de CMO utilisé sur la charge interactionnelle (degré de prise en compte de l'autre et sur la configuration des interactions, ainsi que sur l'efficacité de la télécollaboration. Nous en tirons également des conclusions relatives à l'impact du mode de CMO sur l'entrée des apprenants dans la communauté d'apprentissage qui émerge de chacun des groupes de travail auquel ils appartiennent.In spite of the amount of published research on the use of computer-mediated communication (CMC in second language acquisition (SLA in the past twenty years, few of these studies deal with voice-based CMC (audioconferencing and videoconferencing and with how it compares with text-based CMC. This article aims at bridging this gap by examining and comparing learner-to-learner interactions in L2 English that were generated during the completion of collaborative tasks using three different CMC modes: text chat, desktop videoconferencing and discussion board. The collaborative tasks to be completed were part of a blended learning system

  11. Analysis of the Volatile Constituents of Irradiated Apple Juice; Analyse des Constituants Volatils des Jus de Pommes Irradies; Mezhdunarodnyj proekt po oblucheniyu fruktov i fruktovykh sokov; Analisis de los Componentes Volatiles de los Zumos de Manzana Irradiados

    Energy Technology Data Exchange (ETDEWEB)

    Dubois, P.; Zenz, H.; Stehlik, G.; Kaindl, K. [Agence Europeenne pour l' Energie Nucleaire, Seibersdorf (Austria)

    1966-11-15

    The organoleptic studies and wholesomeness tests that are being carried out as part of the International Programme on the Irradiation of Fruit and Fruit Juices (Seibersdorf Project) entail analysis of the aromatic substances present in irradiated and non-irradiated juice. The volatile substances present in irradiated fruit juices were analysed by gas chromatography, with direct injection of the emitted vapours at ambient temperature and at 60 Degree-Sign C (Weurman's Head Space Technique). The volatile constituents were identified by comparing the amounts retained in the column with those for pure substances and by removing certain constituents from the vapour with the help of chemical reagents. To simplify the analyses, the first tests were carried out on concentrated apple juice from which the volatile substances had been removed before irradiation. Irradiation gave rise to five aldehydes in the normal apple juice (acetaldehyde, isobutyraldehyde, butyraldehyde, isovaldehyde and capronaldehyde), but only three in the concentrated juice (acetaldehyde, isobutyraldehyde and isovaleraldehyde). In addition, 2-butanone appeared in the concentrated juice; however, the peak corresponding to it on the chromatogram was completely masked by the ethanol peak in the case of non-concentrated juice. Furan was also detected, together with traces of two compounds that have not yet been identified. Similar results have been obtained by pasteurization, such as in bottling by heat. (author) [French] Dans le cadre du projet international de recherches sur la conservation des fruits et jus de fruits par irradiation (Seibersdorf), les etudes organoleptiques, de meme que les tests d'innocuite, rendent indispensable l'analyse des substances aromatiques des jus irradies et non irradies. Les substances volatiles des jus de pommes irradies ont ete analysees par chromatographie en phase gazeuse, par injection directe des vapeurs qu'ils emettent, soit a la temperature du laboratoire, soit a 60

  12. Les théories des mouvements sociaux et la dialectique des niveaux : un cadre d’analyse pour l’étude des évolutions d’Al-Qaïda au Maghreb islamique

    Directory of Open Access Journals (Sweden)

    Adib Bencherif

    2013-10-01

    Full Text Available Les théories des mouvements sociaux sont de plus en plus utilisées pour étudier les groupes terroristes. Elles comportent différents niveaux d’analyse: les niveaux macro-analytique, méso-analytique et micro-analytique. Le présent article tente d’adapter ce corpus théorique à l’étude du groupe jihadiste Al-Qaïda au Maghreb islamique (AQMI. En effet, au cours des dernières années, AQMI ne s’est pas développé au Maghreb alors que ses activités ont augmenté exponentiellement dans la région sahélienne, au point d’y développer un sanctuaire pour le groupe au nord du Mali. Le développement d’AQMI au Sahel est-il alors le résultat de choix stratégiques ou celui de dynamiques internes ? Pour expliquer le développement d’AQMI dans la région sahélo-saharienne, l’auteur propose une grille de lecture basée sur les niveaux macro et méso-analytiques et sur leur mise en dialectique. Le niveau macro-analytique met en lumière la structure des opportunités politiques induisant les choix stratégiques d’AQMI et le niveau méso-analytique les dynamiques internes du groupe. La littérature existante sur AQMI étant principalement constituée de monographies et de notes de recherches, l’ambition de cet article est alors de concilier théorie et recherche empirique. Ainsi le cadre d’analyse proposé est inspiré des approches de l’action collective et de la mobilisation des ressources et cherche à améliorer la compréhension des évolutions du groupe. L’étude menée est une analyse qualitative centrée sur les États algérien et malien.The theories of social movements are increasingly used to study terrorist groups and they are characterized by three different levels of analysis: macro, meso, and micro. This article attempts to adapt this theoretical framework to the study of the jihadist group al-Qaeda in the Islamic Maghreb (AQIM. Indeed, in recent years, AQIM failed to develop in North Africa while its

  13. Analyse des erreurs dans les calculs sur ordinateurs Error Analysis in Computing

    Directory of Open Access Journals (Sweden)

    Vignes J.

    2006-11-01

    Full Text Available La méthode présentée ici permet d'évaluer l'erreur sur les résultats d'algorithmes, erreurs dues à l'arithmétique à précision limitée de la machines L'idée de base de cette méthode est qu'à un algorithme donné fournissant un résultat algébrique unique r, correspond en informatique un ensemble R de résultats numériques qui sont tous représentatifs de résultat exact r. La méthode de permutation-perturbation que nous présentons ici permet d'obtenir les éléments de R. La perturbation agit sur les données et résultats de chaque opération élémentaire. La permutation agit sur l'ordre d'exécution des opérations. Une étude statistique des éléments de R permet d'estimer l'erreur commise. Dans la pratique, il suffit de 2 ou 3 éléments de R pour connaître cette erreur. This paper describes a new method for evaluating the error in the results of computation of an algorithm. The basic idea underlying the method is that while in algebra a given algorithm provides a single result r, this same algorithm carried out on a computer provides a set R of numerical results that are ail representative of the exact algebraic result r. The permutation-perturbation method described here can be used to obtain the elements of R. The perturbation acts on the data and results of each elementary operation, and the permutation acts on the order in which operations are carried out. A statistical analysis of the elements of R is performed to determine the error committed. In practice, 2 to 4 R elements are sufficient for determining the error.

  14. Le dysfonctionnement socio-spatial des grands ensembles en Algérie: technique de l’analyse wayfinding par méthode “movement traces” et l’analyse morphologique (syntaxe spatiale par logiciel “depthmap”

    Directory of Open Access Journals (Sweden)

    Amara Hima

    2018-03-01

    Full Text Available Résumé La technique de l’analyse syntaxique de la visibilité (Visibility Graph Analysis – VGA et de l’accessibilité (All Line Analysis – ALA par logiciel “DepthMap©(UCL, Londres” et l’analyse du dysfonctionnement wayfinding par méthode “movement traces”, sont utilisées dans ce papier afin de développer un modèle d’analyse et d’investigation de l’impact des changements spatiaux sur le dysfonctionnement socio-spatial du wayfinding, ainsi sur la reproduction urbaine, notamment les transformations des façades et l’appropriation des espaces extérieurs dans les grands ensembles en Algérie. Nous donnons ici le cas d’étude de la cité 1000 logt-Biskra et la cité 500 logt-M’sila. Afin de vérifier cette hypothèse, un modèle d’analyse hybride a été développé par croisement des résultats d’analyses des deux techniques. Par conséquent, le schéma de l’interférence montre que la majorité des piétons préfèrent parcourir les axes courts et droits — caractérisés par une forte propriété syntaxique de visibilité et d’accessibilité (l’intégration, la connectivité et l’intelligibilité — en directions des équipements adjacents et aux milieux des deux cités. Ces itinéraires ont un impact sur les transformations des façades et l’appropriation des espaces extérieurs. Le modèle développé promet de futures recherches sur le plan de la quantification, la modélisation et la simulation du processus de la reproduction urbaine, notamment par les automates cellulaires.

  15. Spectrochemical analysis of impurities in plutonium and its compounds; L'analyse spectrochimique des impuretes dans le plutonium et ses composes

    Energy Technology Data Exchange (ETDEWEB)

    Buffereau, M; Crehange, G; Deniaud, S; Leclainche, C [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1967-07-01

    After a review of previous works, various powdered or wet analytical methods are studied. One tries to give an explanation for some phenomena. A detailed know-how of studied methods is given. Validity of results is discussed. Problem of impurities in alloys analysis and non spectroscopic elements determination is quickly reviewed. One concludes to the interest of the use of some particular methods and the necessity of basic studies in order to obtain best information. (author) [French] Apres une revue des travaux precedents on etudie les differentes methodes d'analyse soit sur poudre (oxyde), soit sur solution. On tente de donner une interpretation de certains phenomenes. On donne un mode d'emploi detaille des methodes etudiees, on envisage la validite des resultats. On passe en revue rapidement le probleme de l'analyse des impuretes dans les alliages et de la determination des elements non spectroscopiques. On conclut a l'interet de l'emploi de certaines methodes, et a la necessite d'etudes fondamentales en vue d'aboutir a une meilleure obtention des informations. (auteur)

  16. Spectrochemical analysis of impurities in plutonium and its compounds; L'analyse spectrochimique des impuretes dans le plutonium et ses composes

    Energy Technology Data Exchange (ETDEWEB)

    Buffereau, M.; Crehange, G.; Deniaud, S.; Leclainche, C. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1967-07-01

    After a review of previous works, various powdered or wet analytical methods are studied. One tries to give an explanation for some phenomena. A detailed know-how of studied methods is given. Validity of results is discussed. Problem of impurities in alloys analysis and non spectroscopic elements determination is quickly reviewed. One concludes to the interest of the use of some particular methods and the necessity of basic studies in order to obtain best information. (author) [French] Apres une revue des travaux precedents on etudie les differentes methodes d'analyse soit sur poudre (oxyde), soit sur solution. On tente de donner une interpretation de certains phenomenes. On donne un mode d'emploi detaille des methodes etudiees, on envisage la validite des resultats. On passe en revue rapidement le probleme de l'analyse des impuretes dans les alliages et de la determination des elements non spectroscopiques. On conclut a l'interet de l'emploi de certaines methodes, et a la necessite d'etudes fondamentales en vue d'aboutir a une meilleure obtention des informations. (auteur)

  17. Ein Fließgewässer im urbanen Umfeld. Analyse des ökologischen Zustandes des unteren Belmer Baches (Osnabrück, Niedersachsen) anhand des Makrozoobenthos

    DEFF Research Database (Denmark)

    Rasch, Peter; Trapp, Stefan

    2000-01-01

    The organic pollution of the lower Belmer Bach can be attributed to its agriculturally intensively used drainage area. Already before entering the urbanized region, the macrozoobenthos is poor in species due to saprobic pollution and the structural poverty of the waterbed and the banks.......When comparing the species numbers of a reference sampling plot located before the urban region and a sampling plot situated within this region, hardly any differences could be ascertained. The longitudinal isolation and the rise in temperature of i 1 °C in the urban brook section negatively influence its fauna...

  18. Prises de risques chez les jeunes de Bobo Dioulasso: une analyse des facteurs associés à la précocité et au multipartenariat sexuel

    Science.gov (United States)

    Adohinzin, Clétus Come; Meda, Nicolas; Belem, Adrien Marie Gaston; Ouédraogo, Georges Anicet; Sombie, Issiaka; Berthe, Abdramane; Fond-Harmant, Laurence

    2016-01-01

    Introduction Malgré les efforts d'éducation à la santé, les jeunes continuent d'adopter des comportements sexuels à risques, susceptibles d'avoir des répercussions importantes sur leur santé. Cette étude visait à analyser les facteurs associés à la précocité sexuelle et au multipartenariat chez les jeunes de 19-24 ans de Bobo-Dioulasso. Méthodes Il s'agit d'une étude quantitative et transversale. Les données d'enquête ont été recueillies en décembre 2014 à Bobo-Dioulasso (Burkina Faso), auprès de 573 jeunes de 15 à 24 ans. Ces enquêtés ont été sélectionnés par un sondage en grappes à deux degrés. Des facteurs à risques relatifs à la précocité sexuelle et au multipartenariat ont été analysés à l'aide du logiciel Stata IC 13. Le seuil de signification de Psexe, le niveau d'étude, et la situation économique des parents. Nos données avaient aussi montré que les rapports sexuels trop précoces étaient associés au multipartenariat sexuel (p<0,005). Conclusion Les actions visant à renforcer les capacités des jeunes à retarder les premiers rapports sexuels et à mieux évaluer les risques seront de toute importance. Les capacités des parents, des enseignants et des prestataires devraient être aussi renforcées pour l'amélioration de la qualité des relations entre eux et les jeunes. PMID:28292094

  19. Analyse de l'état mécanique et microstructural de films minces supraconducteurs YBa_2 Cu_3O_7 par diffraction des rayons X

    Science.gov (United States)

    Auzary, S.; Badawi, K. F.; Bimbault, L.; Rabier, J.; Gaboriaud, R. J.; Goudeau, Ph.

    1997-01-01

    Mechanical and microstructural analysis in a 100nm thin film is presented in this study. Using X-ray diffraction with a tensorial approach, we have determined stresses, strains, stress-free lattice parameters, microdistorsions and diffracting coherent domains size. Stress-free lattice parameters are higher than the bulk values. A high value of stresses is explained as a combination of coherent stresses, thermal stresses and intrinsic ones. Diffraction peaks line profiles analysis suggests grain boundaries presence as well as high lattice elastic microdistorsions. Cette étude présente une analyse de l'état mécanique et microstructurale dans un film mince de 100nm d'épaisseur d'YBCO déposé sur un substrat de MgO. En utilisant la diffraction des rayons X couplée à une approche tensorielle, nous avons déterminé les déformations, les contraintes, les paramètres libres de contraintes, les microdistorsions élastiques ainsi que la taille des domaines cohérents de diffraction. Les paramètres libres de contrainte sont supérieurs à ceux du massif. Une valeur élevée des contraintes est expliquée à partir des contraintes de cohérence, des contraintes thermiques et intrinsèques. L'analyse des profils des pics de diffraction suggère la présence de sous-joints et de distorsions élastiques élevées au niveau des mailles cristallographiques.

  20. Analyse géochimique des hydrocarbures légers par thermovaporisation Geochemical Analysis of Light Hydrocarbons by Thermovaporization

    Directory of Open Access Journals (Sweden)

    Jonathan D.

    2006-11-01

    Full Text Available Le procédé de thermovaporisation est utilisé pour l'extraction et l'analyse des hydrocarbures à point d'ébullition situé à l'intérieur de l'intervalle correspondant aux alcanes C6 à C15; il s'applique également aux roches et aux huiles. La mise en ceuvre est simple et rapide, ce qui rend cette technique utilisable dans certains laboratoires de chantiers d'exploration. Les chromatogrammes de vapeurs montrent une succession de pics, chaque pic correspondant théoriquement à un composant défini, alcane, cyclane ou aromatique; la portion située entre les alcanes n-C, et n-C8 est très typée, mais le reste du chromatogramme apporte également des informations importantes ; l'ensemble donne une définition chimique très fine des hydrocarbures légers présents dans l'échantillon. L'exploitation de ces informations en interprétation géochimique est multiple (pouvoir pétroligène de sédiments, état de maturation, etc.. La faible masse de la prise d'essai nécessaire constitue un intérêt essentiel de la méthode. The method called thermovaporization is used to extract and analyse low boiling point hydrocarbons in the range corresponding to C6-C15; alcanes. Sediments and oils ore examined in the same way. This method is simple and fast to utilize, and for this reason it can be applied in some field exploration laboratories. Chromatograms show a sertes of peaks, each of them theoretically corresponding to a particular composant : alkane, cyclone, arcmatics. The part of the chromatogram between n-C7 n-C8 is very characteristic, but other parts also provide a great deal of information. The total chromatogram gives a very fine chemical definition of the light hydrocarbons in the sample. This information can be used for many geochemical interpretations (hydrocarbon yield potential, state of maturation, etc.. Moreover, the tiny amount of sample thot is necessary is of major interest.

  1. Nouvelles fonctions de l'agriculture et dynamiques des exploitations: une analyse chorématique dans les monts d'Ardèche

    Directory of Open Access Journals (Sweden)

    Muriel Bonin

    2001-06-01

    Full Text Available Les modèles spatiaux sont utilisés pour l'analyse des trajectoires d'exploitations agricoles pour mettre en évidence les liens entre les transformations socio-économiques et les dynamiques de territoires. Les traits de dynamiques spatiales sont identifiés et utilisés pour analyser l'impact de l'introduction de l'agritourisme dans les exploitations dans le Parc naturel régional des monts d'Ardèche.

  2. IRE (Institut National des Radioelements) site in Belgium. Report of in situ measurements and analyses performed for the RTBF; Site IRE (Institut National des Radioelements) en Belgique. Compte rendu des mesures in situ et analyses effectuees pour la RTBF

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-05-15

    This document reports various analyses performed within the frame of the preparation and filming of a TV documentary on the Belgium National Institute of Radio-elements. It reports gamma radiation measurements performed at the vicinity of the institute, discusses the possible origin of its increase at the vicinity of the institute, analyses of sludge samples coming from a wastewater treatment works, and analyses of milk, cabbage, mosses and sediments collected by residents

  3. Semantics bias in cross-national comparative analyses

    DEFF Research Database (Denmark)

    Schnohr, Christina W.; Gobina, Inese; Santos, Teresa

    2016-01-01

    indicates that there are what may be called semantic issues affecting comparability in international studies, since the same original word (in an English original) is interpreted differently across countries and cultures. The paper test and discuss a few possible explanations to this, however, only leaving...

  4. Comparative and Predictive Multimedia Assessments Using Monte Carlo Uncertainty Analyses

    Science.gov (United States)

    Whelan, G.

    2002-05-01

    Multiple-pathway frameworks (sometimes referred to as multimedia models) provide a platform for combining medium-specific environmental models and databases, such that they can be utilized in a more holistic assessment of contaminant fate and transport in the environment. These frameworks provide a relatively seamless transfer of information from one model to the next and from databases to models. Within these frameworks, multiple models are linked, resulting in models that consume information from upstream models and produce information to be consumed by downstream models. The Framework for Risk Analysis in Multimedia Environmental Systems (FRAMES) is an example, which allows users to link their models to other models and databases. FRAMES is an icon-driven, site-layout platform that is an open-architecture, object-oriented system that interacts with environmental databases; helps the user construct a Conceptual Site Model that is real-world based; allows the user to choose the most appropriate models to solve simulation requirements; solves the standard risk paradigm of release transport and fate; and exposure/risk assessments to people and ecology; and presents graphical packages for analyzing results. FRAMES is specifically designed allow users to link their own models into a system, which contains models developed by others. This paper will present the use of FRAMES to evaluate potential human health exposures using real site data and realistic assumptions from sources, through the vadose and saturated zones, to exposure and risk assessment at three real-world sites, using the Multimedia Environmental Pollutant Assessment System (MEPAS), which is a multimedia model contained within FRAMES. These real-world examples use predictive and comparative approaches coupled with a Monte Carlo analysis. A predictive analysis is where models are calibrated to monitored site data, prior to the assessment, and a comparative analysis is where models are not calibrated but

  5. Comparative Analyses of Phenotypic Trait Covariation within and among Populations.

    Science.gov (United States)

    Peiman, Kathryn S; Robinson, Beren W

    2017-10-01

    Many morphological, behavioral, physiological, and life-history traits covary across the biological scales of individuals, populations, and species. However, the processes that cause traits to covary also change over these scales, challenging our ability to use patterns of trait covariance to infer process. Trait relationships are also widely assumed to have generic functional relationships with similar evolutionary potentials, and even though many different trait relationships are now identified, there is little appreciation that these may influence trait covariation and evolution in unique ways. We use a trait-performance-fitness framework to classify and organize trait relationships into three general classes, address which ones more likely generate trait covariation among individuals in a population, and review how selection shapes phenotypic covariation. We generate predictions about how trait covariance changes within and among populations as a result of trait relationships and in response to selection and consider how these can be tested with comparative data. Careful comparisons of covariation patterns can narrow the set of hypothesized processes that cause trait covariation when the form of the trait relationship and how it responds to selection yield clear predictions about patterns of trait covariation. We discuss the opportunities and limitations of comparative approaches to evaluate hypotheses about the evolutionary causes and consequences of trait covariation and highlight the importance of evaluating patterns within populations replicated in the same and in different selective environments. Explicit hypotheses about trait relationships are key to generating effective predictions about phenotype and its evolution using covariance data.

  6. Comparative analyses of industrial-scale human platelet lysate preparations.

    Science.gov (United States)

    Pierce, Jan; Benedetti, Eric; Preslar, Amber; Jacobson, Pam; Jin, Ping; Stroncek, David F; Reems, Jo-Anna

    2017-12-01

    Efforts are underway to eliminate fetal bovine serum from mammalian cell cultures for clinical use. An emerging, viable replacement option for fetal bovine serum is human platelet lysate (PL) as either a plasma-based or serum-based product. Nine industrial-scale, serum-based PL manufacturing runs (i.e., lots) were performed, consisting of an average ± standard deviation volume of 24.6 ± 2.2 liters of pooled, platelet-rich plasma units that were obtained from apheresis donors. Manufactured lots were compared by evaluating various biochemical and functional test results. Comprehensive cytokine profiles of PL lots and product stability tests were performed. Global gene expression profiles of mesenchymal stromal cells (MSCs) cultured with plasma-based or serum-based PL were compared to MSCs cultured with fetal bovine serum. Electrolyte and protein levels were relatively consistent among all serum-based PL lots, with only slight variations in glucose and calcium levels. All nine lots were as good as or better than fetal bovine serum in expanding MSCs. Serum-based PL stored at -80°C remained stable over 2 years. Quantitative cytokine arrays showed similarities as well as dissimilarities in the proteins present in serum-based PL. Greater differences in MSC gene expression profiles were attributable to the starting cell source rather than with the use of either PL or fetal bovine serum as a culture supplement. Using a large-scale, standardized method, lot-to-lot variations were noted for industrial-scale preparations of serum-based PL products. However, all lots performed as well as or better than fetal bovine serum in supporting MSC growth. Together, these data indicate that off-the-shelf PL is a feasible substitute for fetal bovine serum in MSC cultures. © 2017 AABB.

  7. Method of chemical analysis of silicate rocks (1962); Methode d'analyse chimique des roches silicatees (1962)

    Energy Technology Data Exchange (ETDEWEB)

    Pouget, R [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1962-07-01

    A rapid method of analysis for the physical and chemical determination of the major constituents of silicate rocks is described. Water losses at 100 deg. C and losses of volatile elements at 1000 deg. C are estimated after staying in oven for these temperatures, or by mean of a thermo-balance. The determination of silica is made by a double insolubilization with hydrochloric acid on attack solution with sodium carbonate; total iron and aluminium, both with calcium and magnesium, after ammoniacal precipitation of Fe and Al, are determined on the filtration product of silica by titrimetry-photometry of their complexes with EDTA. The alkalis Na and K by flame spectrophotometry, Mn by colorimetry of the permanganate, and Ti by mean of his complex with H{sub 2}O{sub 2}, are determined on fluosulfuric attack solution. Phosphorus is determined by his complex with 'molybdenum blue' on a fluoro-nitro-boric attack solution; iron is estimated by potentiometry, with the help of bichromate on hydrofluoric solution. (author) [French] Une methode d'analyse rapide est decrite pour la determination physico-chimique des constituants principaux des roches silicatees. Les pertes en eau a 100 deg. C et en matieres volatiles a 1000 deg. C sont evaluees apres passage au four a ces temperatures, ou a l'aide d'une thermobalance. La determination de la silice se fait par double insolubilisation a l'acide chlorhydrique, sur une attaque au carbonate de sodium; le fer total et l'aluminium ainsi que le calcium et le magnesium, apres precipitation a l'ammoniaque des deux premiers metaux, sont determines sur le filtrat de la silice par titrimetrie-photometrie de leurs complexes avec l'E.D.T.A. Les alcalins sodium et potassium par spectrophotometrie de flamme, le manganese par colorimetrie du permanganate, le titane a l'aide de son complexe avec l'eau oxygenee, sont determines sur une attaque fluosulfurique. Le phosphore est determine par son complexe du 'bleu de molybdene' sur une attaque fluo

  8. Etude comparative de la flore aux abords des cours d'eau dans les ...

    African Journals Online (AJOL)

    4 UFR des Sciences biologiques, Université Péléforo Gon Coulibaly, Korhogo. 5 Centre Suisse de ... abords des plans d'eau des zones de forte et de faible endémicité d'UB. L'inventaire ...... modifié pour les besoins de l'agriculture et de.

  9. A tale of two phylogenies: comparative analyses of ecological interactions.

    Science.gov (United States)

    Hadfield, Jarrod D; Krasnov, Boris R; Poulin, Robert; Nakagawa, Shinichi

    2014-02-01

    The evolution of traits involved in ecological interactions such as predator-prey, host-parasite, and plant-pollinator interactions, are likely to be shaped by the phylogenetic history of both parties. We develop generalized linear mixed-effects models (GLMM) that estimate the effect of both parties' phylogenetic history on trait evolution, both in isolation but also in terms of how the two histories interact. Using data on the incidence and abundance of 206 flea species on 121 mammal species, we illustrate our method and compare it to previously used methods for detecting host-parasite coevolution. At large spatial scales we find that the phylogenetic interaction effect was substantial, indicating that related parasite species were more likely to be found on related host species. At smaller spatial scales, and when sampling effort was not controlled for, phylogenetic effects on the number and types of parasite species harbored by hosts were found to dominate. We go on to show that in situations where these additional phylogenetic effects exist, then previous methods have very high Type I error rates when testing for the phylogenetic interaction. Our GLMM method represents a robust and reliable approach to quantify the phylogenetic effects of traits determined by, or defined by, ecological interactions and has the advantage that it can easily be extended and interpreted in a broader context than existing permutation tests.

  10. Comparative exergy analyses of gasoline and hydrogen fuelled ices

    International Nuclear Information System (INIS)

    Nieminen, J.; Dincer, I.; Yang, Y.

    2009-01-01

    Comparative exergy models for naturally aspirated gasoline and hydrogen fuelled spark ignition internal combustion engines were developed according to the second laws of thermodynamics. A thorough graphical analysis of heat transfer, work, thermo mechanical, and intake charge exergy functions was made. An irreversibility function was developed as a function of entropy generation and graphed. A second law analysis yielded a proportional exergy distribution as a fraction of the intake charge exergy. It was found that the hydrogen fuelled engine had a greater proportion of the intake charge exergy converted into work exergy, indicating a second law efficiency of 50.13% as opposed to 44.34% for a gasoline fuelled engine. The greater exergy due to heat transfer or thermal availability associated with the hydrogen fuelled engine is postulated to be a part of the reason for decreased work output of a hydrogen engine. Finally, a second law analysis of both hydrogen and gasoline combustion reactions indicate a greater combustion irreversibility associated with gasoline combustion. A percentage breakdown of the combustion irreversibilities were also constructed according to information found in literature searches. (author)

  11. Retrospective analyses versus RCTs: comparing like with like?

    Directory of Open Access Journals (Sweden)

    Baron R

    2017-03-01

    Full Text Available Ralf Baron,1 Lieven Nils Kennes,2 Christian Elling31Division of Neurological Pain Research and Therapy, Department of Neurology, University Hospital of Schleswig-Holstein, Kiel Campus, Kiel, 2Department of Economics and Business Administration, University of Applied Sciences Stralsund, Stralsund, 3Grünenthal GmbH, Medical Affairs Europe and North America, Aachen, GermanyIn their recent retrospective analysis assessing oxycodone/naloxone (OXN vs. tapentadol (TAP treatment for chronic low-back pain with a neuropathic component, Ueberall and Mueller-Schwefe1 compare their results to the findings of an earlier phase 3b/4 study.2 In our opinion, a proper comparison to the prospective, randomized, controlled, open-label study by Baron and colleagues is scientifically not appropriate. Although Ueberall and Mueller-Schwefe use the terms “prospective,” “randomly,” and “blinded” and refer to the PROBE design (prospective, randomized, open-label, blinded endpoint,3 their database study is retrospective, nonrandomized, and nonblinded with the treatment choice left to the discretion of the physicians. In this context, the use of the term “intention-to-treat (ITT population” is inappropriate because ITT is unambiguously defined as including all randomized subjects and thus inseparable from true randomization (ICH E9.4View original paper by Ueberall and Mueller-Schwefe.

  12. Analyse des effets de deux modalités de constitution des groupes dans un dispositif hybride de formation à distance

    Directory of Open Access Journals (Sweden)

    Christian Depover

    2004-01-01

    Full Text Available Cette étude porte sur les effets de deux modalités de constitution des groupes (spontané versus contrasté dans un dispositif hybride de formation à distance destiné à des étudiants universitaires. Les scénarios d’apprentissage mis en œuvre à l’occasion de cette expérience reposent sur l’utilisation des cartes conceptuelles comme support au travail collaboratif. Les résultats observés n’ont pas permis de mettre en évidence de différence quant à la densité conceptuelle des cartes ou au nombre d’unités de sens produites. Par contre, il apparaît que les unités de sens qui concernent les activités de planification et les commentaires métacognitifs sont nettement plus nombreuses au sein des groupes constitués par pairage contrasté. Une corrélation positive entre l’intensité des interactions à l’intérieur du forum et la densité conceptuelle des cartes produites a également été mise en évidence pour les groupes constitués sur la base d’un pairage contrasté. En ce qui concerne le pairage spontané, nos résultats indiquent que les paires constituées témoignent d’un comportement plus homogène, se révèlent plus collaboratives et consacrent moins d’effort à la planification du travail de groupe.

  13. Next generation sequencing and comparative analyses of Xenopus mitogenomes

    Directory of Open Access Journals (Sweden)

    Lloyd Rhiannon E

    2012-09-01

    Full Text Available Abstract Background Mitochondrial genomes comprise a small but critical component of the total DNA in eukaryotic organisms. They encode several key proteins for the cell’s major energy producing apparatus, the mitochondrial respiratory chain. Additonally, their nucleotide and amino acid sequences are of great utility as markers for systematics, molecular ecology and forensics. Their characterization through nucleotide sequencing is a fundamental starting point in mitogenomics. Methods to amplify complete mitochondrial genomes rapidly and efficiently from microgram quantities of tissue of single individuals are, however, not always available. Here we validate two approaches, which combine long-PCR with Roche 454 pyrosequencing technology, to obtain two complete mitochondrial genomes from individual amphibian species. Results We obtained two new xenopus frogs (Xenopus borealis and X. victorianus complete mitochondrial genome sequences by means of long-PCR followed by 454 of individual genomes (approach 1 or of multiple pooled genomes (approach 2, the mean depth of coverage per nucleotide was 9823 and 186, respectively. We also characterised and compared the new mitogenomes against their sister taxa; X. laevis and Silurana tropicalis, two of the most intensely studied amphibians. Our results demonstrate how our approaches can be used to obtain complete amphibian mitogenomes with depths of coverage that far surpass traditional primer-walking strategies, at either the same cost or less. Our results also demonstrate: that the size, gene content and order are the same among xenopus mitogenomes and that S. tropicalis form a separate clade to the other xenopus, among which X. laevis and X. victorianus were most closely related. Nucleotide and amino acid diversity was found to vary across the xenopus mitogenomes, with the greatest diversity observed in the Complex 1 gene nad4l and the least diversity observed in Complex 4 genes (cox1-3. All protein

  14. Analyse géopolitique et diplomatie au XVIe siècle. La qualification de l’ennemi dans les relazioni des ambassadeurs vénitiens

    Directory of Open Access Journals (Sweden)

    Romain Descendre

    2007-02-01

    Full Text Available Cet article examine la textualité des relations des ambassadeurs vénitiens du xvie siècle. S’attachant en particulier à la partie finale des relazioni, traditionnellement consacrée aux amitiés et inimitiés princières, l’analyse rend visible la façon dont ces discours constituent l’une des premières matrices de la pensée des relations internationales à l’époque moderne.

  15. Analyse sédimentologique des 'Couches Rouges' du bassin intramontagneux de Sicuani (Sud du Pérou

    Directory of Open Access Journals (Sweden)

    1987-01-01

    Full Text Available Le bassin des 'Couches Rouges' de Sicuani (sud du Pérou est un bassin continental intramontagneux dont le fonctionnement débute dès les premiers mouvements tectoniques andins du Sénonien. La sédimentation est essentiellement d'origine fluviatile. Les termes les plus proximaux sont représentés par les rivières en tresse à galets et les plus distaux par la plaine d'inondation à chenaux divagants. Le sens constant des apports sédimentaires implique une paléopente régionale inclinée vers le nord. A cette époque, la principale source des sédiments n'est donc pas représentée par la Cordillère orientale mais plutôt par les reliefs situés au sud-ouest des affleurements. Le taux de sédimentation relativement élevé, le guidage des transits sédimentaires par d'anciennes failles majeures et l'existence de structures de déformation synsédimentaire compressives font du bassin de Sicuani un bassin tectoniquement actif, comparable à celui de Cuzco. La première phase tectonique andine ne correspond donc plus à un événement ponctuel mais bien au contraire à un continuum tectonique en compression au cours duquel se développe la sédimentation des 'Couches Rouges' sud péruviennes. Ce continuum tectonique est associé à une activité volcanique intermittente, en partie responsable de l'alimentation des bassins. La cuenca de las 'Capas Rojas' de Sicuani (sur del Perú es una cuenca continental intramontañosa cuyo funcionamiento empezó desde los primeros movimientos tectónicos andinos del Senoniano. La sedimentación tiene un origen fundamentalmente fluviátil. Los términos más proximales corresponden a ríos en trenza con cantos y los más distales a la llanura de inundación con canales divagantes. La permanencia del sentido de los aportes sedimentarios implica la existencia de una paleopendiente regional inclinada hacia el norte. Es así como, en esta época, la fuente principal de los sedimentos no estuvo representada por

  16. Comprendre la construction des usages des TIC en formation : Vers un modèle d'analyse systémique

    OpenAIRE

    POYET , FRANCOISE

    2014-01-01

    Mémoire de HDR présenté et soutenu publiquement le 24 avril 2014 par Françoise POYETDepuis quelque trente ans, les Technologies de l’Information et de la Communication ont pris un essor considérable dans le monde professionnel et dans la plupart des activités de la vie quotidienne. Cet essor ne semble pas aussi rapide en ce qui concerne les domaines de l’éducation et de la formation dans lesquels les TIC prennent davantage de temps à s’intégrer durablement aux pratiques professionnelles des e...

  17. Nouvelles analyses des crises alimentaires en Afrique de l'Ouest

    Directory of Open Access Journals (Sweden)

    Janin, P.

    2015-01-01

    Full Text Available New analyses of food crises in West Africa. The issue of crisis is a central element of debate and a strategic challenge for all stakeholders in West Africa. Food and nutrition crises are recurrent in the region, with a level of intensity and high variability constituting renewed challenges. The definition, delimitation and management of these crises are provided by an established and structured professional field, which favors intervention. Different conceptual and contextual approaches can be mobilized to account for the diversity and complexity of food and nutrition crises. Some more descriptive approaches list the causes and manifestations of these crises, while others insist on the fact that they are created, and identify their dynamic as being linked to interactions between various phenomena. To date, most of the various institutional actors involved in addressing food and nutrition crises, both at national and international levels, have favored the gradual improvement of expert systems providing technical short-term responses. In parallel, this has led to a harmonization of these frameworks of thought, which has been detrimental to the consideration of the diversity of questions and the integration of non-institutional actors. These are the boundaries and limitations that this article aims to question, in order to reinvoke the political dimension of the management of food crises (and their eventual resolution.

  18. Analyse des systèmes de gestion des déchets par l’étude du mécanisme de répartition des déchets

    OpenAIRE

    Bergeron, Francis

    2015-01-01

    Le renforcement de l’usage concurrentiel des déchets nous amène à étudier les processus d’approvisionnement des filières de valorisation et d’élimination sous l’angle de la circulation des flux de déchets au sein d’un système de gestion des déchets. L’objectif du présent article de recherche est de concevoir un cadre théorique autour du concept de mécanisme de répartition des déchets qui désigne le processus de distribution des flux de déchets entre les filières d’élimination et de valorisati...

  19. Production, analyse et applications des huiles végétales en Afrique

    Directory of Open Access Journals (Sweden)

    Kapseu César

    2009-07-01

    Full Text Available This paper analyses the evolutions of the different needs related to the food and non food uses of conventional oil crops (palm, cotton, groundnuts, immerging and marketable oil culture (shea as well as the domestic oil cultures (Canarium, safou. Africa accounts for about 6.5% of the total World production of palm oil. In the last few years palm oil has witnessed an evolution in Africa through the diversification of its uses. A lot has also been done on the use of palm oil as bio-fuels. The production of cotton seed oil has equally witnessed changes from press extraction followed by solvent extraction to direct extraction with pure solvents followed by neutralisation in an appropriate medium as major innovations. West Africa produces about 50% of the total groundnuts production in Africa. Small scale processing of groundnuts is more popular than industrial processing. This is justified by the diverse uses of the different groundnut byproducts. The most remarkable innovations concern the emerging oil cultures such as shea butter. In fact the incorporation of 5% shea butter in chocolate formulations has given an added value to shea. Techniques have been put in place for improving on the production methods and quality of the butter. The evolution in this sector is better illustrated by the putting in place of an indirect solar dryer and a vertical manual screw press. The big handicap that slows down evolution remains at the level of the transfer of technology to the rural milieu. Problems on the transfer preservation of Canarium were resolved by preserving them in appropriate media and conditions. Dried safou fruits can now be found in the market. This illustrates the appropriation of technology by small and medium sized enterprises.

  20. Analyse des kérosènes et des gas oils moyens par spectrométrie de masse à moyenne résolution Analysis of Kerosenes and Middle Distillates by Medium-Resolution Mass Spectrometry

    Directory of Open Access Journals (Sweden)

    Castex H.

    2006-11-01

    Full Text Available Une méthode d'analyse par spectrométrie de masse des kérosènes et des distillats moyens dérivée de la norme ASTM D2425, a été développée. Elle utilise le même principe de calcul du carbone moyen pour déterminer le choix des matrices appropriées. Mais elle opère à moyenne résolution, effectuant ainsi le tri des différentes masses exactes d'hydrocarbures, composés soufrés et oxygénés et évitant de ce fait toute séparation préalable par chromatographie liquide (ASTM D2 549 . Les valeurs des matrices ont été modifiées en conséquence et le calcul du carbone moyen adapté à l'étude des coupes étroites et larges. A mass-spectrometry analysis method derived from the ASTM D2425 standard has been developed for kerosenes and middle distillates (185-345°C. It uses the same principle for calculating the mean carbon value to determine the appropriate matrices. But it works with medium reso-lution so as to sort out the different exact masses of hydrocarbons, sulfur and oxygenated compounds, thus avoiding any prior separation by liquid chromatography (ASTM D2549. Therefore, the matrix values have been modified, and the calculation of the mean carbon value has been adapted for analyzing narrow and wide distillation cuts.

  1. Comparative evaluation of three capripoxvirus-vectored peste des petits ruminants vaccines.

    Science.gov (United States)

    Fakri, F; Bamouh, Z; Ghzal, F; Baha, W; Tadlaoui, K; Fihri, O Fassi; Chen, W; Bu, Z; Elharrak, M

    2018-01-15

    Sheep and goat pox (SGP) with peste des petits ruminants (PPR) are transboundary viral diseases of small ruminants that cause huge economic losses. Recombinant vaccines that can protect from both infections have been reported as a promising solution for the future. SGP was used as a vector to express two structural proteins hemagglutinin or the fusion protein of PPRV. We compared immunity conferred by recombinant capripoxvirus vaccines expressing H or F or both HF. Safety and efficacy were evaluated in goats and sheep. Two vaccine doses were tested in sheep, 10 4.5 TCDI50 in 1ml dose was retained for the further experiment. Results showed that the recombinant HF confers an earlier and stronger immunity against both SGP and PPR. This recombinant vaccine protect also against the disease in exposed and unexposed sheep. The potential Differentiating Infected from Vaccinated Animals of recombinant vaccines is of great advantage in any eradication program. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. Conception, analyse et caracterisation des proprietes mecaniques de ressorts composites a renfort tresse

    Science.gov (United States)

    Zebdi, Oussama

    High performance composites reinforced by woven or braided fabrics have several different applications in various fields such as in the aerospace, automobile and marine industry. This research project was carried out at the Ecole Polytechnique de Montreal in collaboration with an industrial sponsor, the company Composites Atlantic Ltd. Composite springs often represent an interesting alternative, given the reduction in weight that they allow with equal mechanical performance compared to metallic springs. Their good resistance to fatigue and corrosion bring additional benefits in several industrial applications. Moreover, the use of the composites increases safety by avoiding the risks of brutal rupture because of the low propagation velocity of cracks in this type of material. Lastly, in electrotechnics, another significant advantage comes into play because of the electrical insulation capability of composite springs. Few research results can be found on composite springs in the scientific literature. The first part of this thesis studies the problems connected with the design of composite springs. The results are promising, because it was confirmed that composite springs can be devised with the same mechanical performance in term of stiffness as metallic ones. Two solutions were found to replace the metallic springs of the suspension of a four wheel drive: the first spring was in carbon-epoxy, and the second one in glass-epoxy. In the second part, software was developed in order to devise a new approach to predict the mechanical properties of woven or braided composites. This work shows how an inverse method based on plate laminate theory allows creating, from experimental results on braided composites, a virtual basic ply that includes the effect of fiber architecture (undulation and braiding angle). Using this model, the properties of the composite can be predicted for any braid angle. The comparison with the experimental results shows a good correlation with

  3. Comparative biochemical analyses of venous blood and peritoneal fluid from horses with colic using a portable analyser and an in-house analyser.

    Science.gov (United States)

    Saulez, M N; Cebra, C K; Dailey, M

    2005-08-20

    Fifty-six horses with colic were examined over a period of three months. The concentrations of glucose, lactate, sodium, potassium and chloride, and the pH of samples of blood and peritoneal fluid, were determined with a portable clinical analyser and with an in-house analyser and the results were compared. Compared with the in-house analyser, the portable analyser gave higher pH values for blood and peritoneal fluid with greater variability in the alkaline range, and lower pH values in the acidic range, lower concentrations of glucose in the range below 8.3 mmol/l, and lower concentrations of lactate in venous blood in the range below 5 mmol/l and in peritoneal fluid in the range below 2 mmol/l, with less variability. On average, the portable analyser underestimated the concentrations of lactate and glucose in peritoneal fluid in comparison with the in-house analyser. Its measurements of the concentrations of sodium and chloride in peritoneal fluid had a higher bias and were more variable than the measurements in venous blood, and its measurements of potassium in venous blood and peritoneal fluid had a smaller bias and less variability than the measurements made with the in-house analyser.

  4. Developpement d'un modele analytique pour l'analyse en elasticite lineaire de champs de deformation et contrainte au sein d'un polycristal. comparaison avec la methode des elements finis =

    Science.gov (United States)

    Bretin, Remy

    L'endommagement par fatigue des materiaux est un probleme courant dans de nombreux domaines, dont celui de l'aeronautique. Afin de prevenir la rupture par fatigue des materiaux il est necessaire de determiner leur duree de vie en fatigue. Malheureusement, dues aux nombreuses heterogeneites presentes, la duree de vie en fatigue peut fortement varier entre deux pieces identiques faites dans le meme materiau ayant subi les memes traitements. Il est donc necessaire de considerer ces heterogeneites dans nos modeles afin d'avoir une meilleure estimation de la duree de vie des materiaux. Comme premiere etape vers une meilleure consideration des heterogeneites dans nos modeles, une etude en elasticite lineaire de l'influence des orientations cristallographiques sur les champs de deformations et de contraintes dans un polycristal a ete realisee a l'aide de la methode des elements finis. Des correlations ont pu etre etablies a partir des resultats obtenus, et un modele analytique en elasticite lineaire prenant en compte les distributions d'orientations cristallographiques et les effets de voisinage a pu etre developpe. Ce modele repose sur les bases des modeles d'homogeneisation classique, comme le schema auto-coherent, et reprend aussi les principes de voisinage des automates cellulaires. En prenant pour reference les resultats des analyses elements finis, le modele analytique ici developpe a montre avoir une precision deux fois plus grande que le modele auto-coherent, quel que soit le materiau etudie.

  5. Proton-MR-spectroscopy of vertebral bone marrow: normal age- and sex-related patterns; Protonen-MR-Spektroskopie des Wirbelkoerpermarks. Analyse des physiologischen Signalverhaltens

    Energy Technology Data Exchange (ETDEWEB)

    Jung, C.M.; Kugel, H.; Schulte, O.; Heindel, W. [Koeln Univ. (Germany). Inst. und Poliklinik fuer Radiologische Diagnostik

    2000-08-01

    Background. Magnetic resonance imaging has shown to be a sensitive method for diagnostics of the red bone marrow, the composition of which changes physiologically and during pathological processes. However, the interpretation of MRI in patients with disorders of the red bone marrow is very difficult. The aim of this study was the characterization of the proton spectrum of healthy bone marrow and its age- and sex-dependent changes to obtain a data basis for measurements in patients. Methods. 154 healthy volunteers have been examined. After imaging, a spectroscopic measurement was performed to determine the relative intensities of fat and water, and their respective T2 times. Results. While T2 (water: 46.9 ms and fat: 75.4 ms) does not depend on age or sex, the relative signal intensity of fat increases by about 6% per decade. In the age groups between 31 and 50 years it diverses significantly between men (43.5%) and woman (32.5%) (p{<=}0.01, Mann-Whitney-Test). Conclusions. Proton spectroscopy can increase the reliability of diagnosis by offering information on composition of the marrow. The analysis of spectroscopic measurements requires exact knowledge about normal physiological values. (orig.) [German] Hintergrund. Die Magnetresonanztomographie ist ein sensitives bildgebendes Verfahren zur Beurteilung des roten Knochenmarkraums. Die Zusammensetzung des Knochenmarks aendert sich mit zunehmenden Alter, aber auch bei krankhaften Prozessen. Als Basis fuer die Interpretation von Patientenuntersuchungen bei Erkrankungen des haematopoetischen Systems wurden im Rahmen der vorliegenden Studie an Probanden die alters- und geschlechtsabhaengigen Veraenderungen des Protoenenspektrums aus dem Knochenmarkraum analysiert. Methode. Bei 154 gesunden Probanden wurde nach einer MR-Bildgebung eine spektroskopische Messung des Lendenwirbelkoerpermarks zur Bestimmung der relativen Fett- und Wasseranteile sowie der T2-Relaxationszeiten durchgefuehrt. Ergebnis. Die T2-Zeiten (46,9 ms

  6. Utilisation des courbes de débit fractionnaire pour l'analyse des phénomènes de récupération par tensio-actif Using Fractional Flow Curves to Analyze Surfactant Recovery Phenomena

    Directory of Open Access Journals (Sweden)

    Moulu J. C.

    2006-11-01

    Full Text Available La connaissance des relations débit fractionnaire-saturation obtenues à partir des courbes de perméabilité relative a permis : - d'expliquer les mécanismes de formation et de propagation des différentes phases mobiles (eau et huile en place, phase aqueuse contenant du tensio-actif et/ou de polymère ; - de prévoir l'allure des courbes de récupération (en particulier la composition et le moment d'arrivée du banc d'huile en déplacement secondaire ou tertiaire ; ces courbe concordent sensiblement avec celles que l'on obtient à partir d'expériences de récupération ; - de tenir compte du volume du bouchon du tensio-actif injecté ; - les paramètres des solutions injectées (tension interfaciale, viscosité, adsorption. . . ayant un effet sur la forme des profils de débit fractionnaire, de mettre en relief le points importants pour l'optimisation des déplacements. Ce type d'analyse par lequel on traite ici un nombre limité de cas peut être généralisé et servir à contrôler les résultats d'expériences ou de simulations numériques. Knowing the fractional flow-saturation relations obtained from relative-permeability curves has made it possible: - to explain the formation and propagation mechanisms of different mobile phases (water and oil in place, aqueous phase containing surfactant and/or polymer ; - to predict the shape of recovery curves (in particular the composition and arrival time of the oil bank for secondary or tertiary recovery; these curves more or less agree with the ones obtained from recovery experiments; - to take into consideration the volume of the surfactant slug injected; - to highlight the important points for optimizing displacements using the parameters of injected solutions (interfacial tension, viscosity, adsorption, etc. having an effect on the shape of fractional flow profiles. This type of analysis, in which a limited number of cases are dealt with here, can be generalized and used to check the

  7. Analyse de qualité d’un MOOC : le point de vue des étudiants

    Directory of Open Access Journals (Sweden)

    Normand Roy

    2016-01-01

    Full Text Available L’engouement qui faisait déclarer au New York Times que 2012 était l’« année du MOOC » semble désormais faire place au regard plus critique que porte la recherche sur le phénomène. En ce sens, le défi de la qualité est aussi important dans les MOOC que dans le domaine de la FAD. La présente recherche a pour objectif d’examiner l’appréciation que 631 apprenants font de leur expérience de deux MOOC du HEC Montréal, à partir de leurs perceptions et d’une approche inductive non préalablement fondée sur des a priori théoriques, à l’aide de trois questions ouvertes. Il émerge des résultats des critères d’évaluation se rapprochant de ceux utilisés dans les cadres de qualité en FAD, mais opérationnalisés d’une manière très spécifique. Ainsi, une attention toute particulière devrait être accordée au contenu (liens théorie-pratique, accessibilité des contenus, aux prestations enseignantes et à la clarté des tests.

  8. The Psychology of Violent Conflict in Failing States: A Review of the Scientific Literature (Psychologie des Conflits Violents au sein d’etats en Deroute: Analyse de Publications Scientifiques)

    Science.gov (United States)

    2010-12-01

    Sommaire ..... Psychologie des conflits violents au sein d’états en déroute: Analyse de publications scientifiques Donald M. Taylor; Michael J. A...in parenthesis at the end of the title) The Psychology of Violent Conflict in Failing States (U) Psychologie des conflits violents au sein d’états en

  9. JournalBase - Une étude comparative internationale des bases de données des revues scientifiques en sciences humaines et sociales (SHS

    Directory of Open Access Journals (Sweden)

    Christine Kosmopoulos

    2009-06-01

    Full Text Available Pour la première fois en 2009 ont été ici présentés dans un tableau comparatif les contenus des bases de données qui recensent les revues en sciences humaines et sociales (SHS, du Web of Science (publié par Thomson Reuters et de Scopus (publié par Elsevier ainsi que des listes de référence European Reference Index for Humanities (ERIH (publiée par la Fondation européenne pour la Science et de l'AERES. Avec quelque 20 000 entrées, c’est une vue quasi exhaustive de la richesse des publications en sciences humaines et sociales qui est enfin apportée par ce tableau. La nomenclature adoptée pour classer les revues par discipline est celle en 27 postes de la Fondation Européenne pour la Science. Les affectations multiples révèlent la multidisciplinarité des revues, assez fréquente en SHS, mais parfois aussi les incohérences des bases de données qui n’ont pas été rectifiées.La recherche a été réalisée en 2008 avec le soutien financier du TGE Adonis du CNRS.Une mise à jour prochaine sera proposée en ligne.L’objectif final de ce projet, qui concerne l'ensemble de la communauté internationale en SHS, était de mettre en ligne, en version bilingue anglais/français, la base de données de JournalBase en mode interactif sur une plate-forme collaborative ainsi que le rapport final de l’étude, afin que les décideurs, les scientifiques, les experts de l'information scientifique disposent d’informations à jour et qu’ils puissent contribuer à faire avancer la réflexion sur ces questions, par l’échange d’expériences et de bonnes pratiques d’utilisation.Un article présentant l'historique du projet, la méthodologie mise en place et les difficultés rencontrées dans la comparaison des données a été publié le 8 janvier 2010. Il analyse également les premiers résultats.Désormais vous pouvez accéder à l'information intégrale de JournalBase sur le site : http://journalbase.cnrs.fr

  10. Analyse du rôle que jouent les réseaux aux yeux des entreprises de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    26 nov. 2013 ... ... suggérant ainsi que les responsables des politiques devraient encourager la création de liens internationaux. Les études ont été publiées dans le quatrième numéro du volume 11 de l'International Journal of Business and Globalization. Il s'agissait d'un numéro spécial sur les réseaux des entreprises du ...

  11. Dynamique des ressources naturelles dans le Parc national de Manda: Cartographie et analyse pour le Développement durable

    Science.gov (United States)

    Ballah Solkam, Rosalie; Médard, Ndoutorlengar

    2018-05-01

    Au Tchad, le réseau d'aires protégées couvre près de 10,2% de la surface du pays et reste globalement représentatif de toute la diversité des écosystèmes de la région. Cependant, ce réseau n'est pas constitué d'écosystèmes intacts car de nombreuses altérations y ont été apportés (certaines espèces sont déjà au seuil critique d'extinction (Addax, gazelle dama, lamantin), voire ont disparu (Rhinocéros noir et blanc, Oryx)) surtout dans les parcs nationaux. Ce qui nous amène à nous interroger sur la dynamique des ressources naturelles et le degré de conservation du parc national de Manda? Une évaluation de la diversité biologique et des ressources hydrographiques de 1951 à 1999 sur la base de la bibliographie existante, de la carte topographique de 1956, des images satellitaires Landsat 5 et 7 TM et ETM+ de 2 périodes (1986, 1999), complétée par des interviews semi-structurés et des transects sur le terrain, permettra de mieux appréhender la dynamique des ressources et les actions de conservation de la biodiversité réalisées à cet effet. Les résultats montrent une dynamique progressive de la faune de 1951 à 1970, puis une dynamique régressive de 1970 à 1989. Après cette tumultueuse période, un repeuplement du parc s'opère de 1989 à 2002. Par contre, la flore est relativement bien conservée avec quelques cours d'eau, des mares, champs et plantations. Et cela grâce aux multiples projets de conservation de la biodiversité. La promotion de l'écotourisme serait une alternative au développement durable de ce parc.

  12. Analyse du capital humain : diagnostic des dépenses d'éducation au Sénégal

    OpenAIRE

    Youssouph Ba

    2011-01-01

    Le but de notre travail consistait dans un premier temps à revisiter les soubassements théoriques du capital humain et savoir si l'augmentation du capital humain a un effet ponctuel sur la croissance économique (aussi bien dans la sphère des pays industrialisés que dans celle des pays en développement). Dans un second temps, il consistait à mesurer la politique du Sénégal en terme de capital humain : mesurer les efforts de financement de l'éducation d'une part et d'autre part, voir si ces eff...

  13. Etude physico-chimique et minéralogique comparative des ...

    African Journals Online (AJOL)

    La valorisation des ressources locales constitue un impératif afin d'atteindre des objectifs de développement durable. Cette étude a consisté à évaluer les caractéristiques physiques, chimiques et minéralogiques d'une argile provenant de Mbodiène (Sénégal), l'attapulgite, comparativement avec un médicament ...

  14. Analyse complète et systématique des protéines mutantes p53 dans ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Une fois l'identification terminée, l'objectif ultime est de cribler des composés qui perturbent ces interactions afin de trouver de nouvelles stratégies thérapeutiques pour traiter les patients qui présentent ces mutations ... Sinai Health System.

  15. Analyse des difficultés de l’expression orale Chez des collégiens algériens

    OpenAIRE

    BEKARA, Nacéra

    2014-01-01

    Ce mémoire se compose de trois parties, la première est consacrée à la définition des concepts théoriques : l’expression orale et la communication, dans la deuxième partie, on a analysé les difficultés rencontrées par les élèves du collège. La troisième partie contient les activités proposées pour favoriser un bon fonctionnement de la communication en classe de langue étrangère. L’objectif de notre travail est d’aider les élèves à améliorer leur compétence de communiquer, de s’exprimer ...

  16. "Si le fleuve se tord, que le crocodile se torde" : une analyse des systèmes agraires de la région nord-ouest du Burkina Faso à l'aide des modèles de programmation mathématique

    NARCIS (Netherlands)

    Maatma, Arnoldus Johannes

    2000-01-01

    Le présente étude a pour but d'analyser les perspectives d'intensification durable des systemes de production agricole dans la région Nord-Quest du Burkina Faso par des techniques a faibles couts. Zie: Résumé

  17. Une méthodologie d'analyse des effets de la globalisation sur les systèmes régionaux locaux

    Directory of Open Access Journals (Sweden)

    Silvana Lombardo

    1999-06-01

    Full Text Available Ce travail a pour but d'enrichir les études concernant les répercussions du changement de l'économie de l'entreprise au niveau global sur les modèles d'organisation territorial au niveau local les entreprises. La recherche part du constat d'une insuffisance du cadre d'étude et d'un manque d'information systématique généralisé. Dans ce but nous avons essayé d'approfondir certains aspects théoriques relatifs d'une part au modèle de réseau que relie les composantes du système territorial, et d'autre part aux effets de globalisation de l'entreprise.Nous avons abordé l'analyse des systèmes industriels de deux régions de l'Italie - les Abbruzes et le Lazio - très peu étudiées mais qui, dans les années dernières, ont montré de grands changements, notamment en ce qui concerne les PME et la formation de véritables systèmes locaux organisés afin de répondre d'une façon très active aux mutations du système économique global.L'analyse s'appuie sur une enquête directe par questionnaire adressée à un échantillon d'entreprises. La loi sur "la privacy" nous a contraintes à employer les données traditionnelles de l'Institut Central de Statistiques et de l'Union des Chambres de Commerce, à partir desquelles nous avons défini l'univers statistique et construit un échantillon représentatif.Les connaissances produites par l'analyse des données permettent de déterminer les formes des questions et d'identifier les aspects devant être approfondis. Les premières conclusions portent en particulier sur les facteurs principaux des choix de localisation de l'entreprise.

  18. Analyse quantitative des effluents de pyrolyse en milieu ouvert et fermé Quantitative Analysis of Pyrolysis Effluents in an Open and Closed System

    Directory of Open Access Journals (Sweden)

    Behar F.

    2006-11-01

    Full Text Available Dans la première partie de l'article, nous décrivons une technique de pyrolyse en milieu ouvert qui permet de caractériser les matières organiques complexes comme le kérogène, le charbon, les asphaltènes de roche et d'huiles, les substances humiques et fulviques etc. Les effluents de pyrolyse sont récupérés et fractionnés quantitativement puis analysés par des techniques spécifiques comme la chromatographie en phase gazeuse et le couplage chromatographie/spectrométrie de masse. Dans la deuxième partie, est présentée une technique de pyrolyse en milieu fermé pour simuler au laboratoire l'évolution thermique des kérogènes, asphaltènes ou huiles. Nous nous sommes surtout attachés à dresser des bilans massiques et des bilans de l'hydrogène sur l'ensemble des produits de pyrolyse. Pour cela, nous avons distingué cinq classes de poids moléculaire croissant : C1, C2-C5, C6-C13, C14+ et coke. La récupération quantitative et la séparation de chacune des cinq fractions permet une analyse moléculaire détaillée de chacune d'elles. The first part of this article describes an open pyrolysis system in order to characterize complex organic matter such as kerogen, coal, rock and oil asphaltenes and humic substances, etc. Pyrolysis effluents are recovered, fractionated quantitatively by liquid chromatography, and then they are analyzed by specific techniques such as gas chromatography and chromatography/mass-spectrometry coupling. The second part describes a pyrolysis technique in a closed system, used for the laboratory simulation of the thermal evolution of kerogens, asphaltenes or oils. A special effort has been made to give the mass and hydrogen balances for all pyrolysis products. For this, five classes have been distinguised with increasing molecular weight: C1, C2-C5, C6-C13, C14+ and coke. The quantitative recovery and the separation of each of the five fractions is used to make a detailed molecular analysis of each of

  19. The necessity for comparative risk analyses as seen from the political point of view

    International Nuclear Information System (INIS)

    Steger, U.

    1981-01-01

    The author describes the current insufficient utilization of risk analyses in the political decision process and investigates if other technologies encounter the same difficulties of acceptance as in the nuclear energy field. This being likely he is trying to find out which contribution comparative risk analyses could make to the process of democratic will-formation so that new technologies are accepted. Firstly the author establishes theses criticizing the recent scientific efforts made in the field of risk analyses and their usability for the political decision process. He then defines the criteria risk analyses have to meet in order to serve as scientific elements for consultative political discussions. (orig./HP) [de

  20. 108 Étude bactériologique comparative des fromages frais ...

    African Journals Online (AJOL)

    AKA BOKO

    Youness CHBAB1, Abdelhak DRIOUICH1, Zakaria MENNANE2 et Mohammed OUHSSINE1. 1Laboratoire de Biotechnologie, Environnement et Qualité, Département de Biologie, Faculté des Sciences,. Université Ibn Tofaïl, BP 133, 14000 Kenitra, Maroc. 2Institut National d'Hygiène, Avenue Ibn Battouta, Rabat, Agdal, BP ...

  1. Sexualité des adolescents et concurrence des classes sociales : étude comparative entre les États-Unis et les Pays-Bas depuis les années 1880

    NARCIS (Netherlands)

    Wouters, Cas

    2014-01-01

    Cette étude a pour but de comparer l’évolution du processus sociologique des bonnes sociétés néerlandaises et américaines depuis les années 1880, alors que les usages pour faire la cour étaient encore sous le contrôle strict des parents. Elle décrit de quelle manière le système de rendez-vous aux

  2. Le pouvoir normatif de Google. Analyse de l’influence du moteur sur les pratiques des éditeurs

    OpenAIRE

    Sire, Guillaume

    2016-01-01

    Dès lors qu’un éditeur souhaite que les documents qu’il a produits soient aussi visibles que possible, la méthode employée par le moteur Google pour hiérarchiser les informations est susceptible d’influencer ses pratiques. Or il se trouve que, paradoxalement, cette influence ne va pas toujours dans le sens des intérêts de l’entreprise Google. Nous expliquons pourquoi, avant d’expliquer comment les concepteurs du moteur essayent d’orienter l’influence qu’ils exercent sur la production éditoria...

  3. Etude comparative d'efficacité de prétraitement des effluents d'une ...

    African Journals Online (AJOL)

    INSPIRON

    1 litre d'eau à traiter avec un coagulant commercial (sulfate d'aluminium) à des doses croissantes (0 à 1.2 g/litre d'eau à traiter) et jumelées séparément à une concentration unique et constante d'adjuvant de floculation. (polyélectrolyte SP6) de 1 mg/l. Le temps global d'un essai est de 50 minutes. Il correspond à 5 minutes ...

  4. L'analyse de cycles de vie (ACV des systèmes d’assainissement : un outil complémentaire d’aide à la décision

    Directory of Open Access Journals (Sweden)

    RISCH, Eva

    2012-12-01

    Full Text Available Dans le domaine de l’assainissement, l’analyse de cycle de vie (ACV se positionne de plus en plus comme un outil décisionnel du choix des filières de traitement et de leur gestion technique. Cet article nous présente ici les résultats d’ACV obtenus en petites et moyennes collectivités pour des stations d’épuration à boues activées en très faible charge et des filtres plantés de roseaux.

  5. Examen d'analyses récentes portant sur l'Étude canadienne sur l'incidence des signalements de cas de violence et de négligence envers les enfants (ECI

    Directory of Open Access Journals (Sweden)

    D. Potter

    2015-01-01

    Full Text Available Introduction : Cette analyse a comme objectif de rassembler les articles évalués par les pairs utilisant des données tirées de l'Étude canadienne sur l'incidence des signalements de cas de violence et de négligence envers les enfants (ECI publiées depuis novembre 2011 ainsi que des suréchantillons provinciaux de l'ECI, d'évaluer la qualité de leurs conclusions, de les synthétiser et de faire le bilan des variations dans l'utilisation de ces données. Méthodologie : Nous avons sélectionné les articles au moyen du suivi des demandes d'accès aux données de l'ECI effectué par l'Agence de la santé publique du Canada et au suivi des publications produites au moyen de ces données. Deux évaluateurs au moins ont examiné de façon indépendante les articles et en ont évalué la qualité. Résultats : Nous avons conservé 32 articles. Leurs points forts étaient en général les suivants : objectifs de recherche clairement établis, variables de contrôle appropriées, analyses pertinentes, taille de l'échantillon suffisante, conclusions pertinentes et utilité pour les pratiques et politiques. Leur point problématique était le plus souvent une définition floue des variables et des critères d'inclusion des cas. La plupart du temps, les articles mesuraient les associations entre les caractéristiques des mauvais traitements et celles des enfants, des pourvoyeurs de soins, du ménage et de l'organisme ou de la personne à l'origine du signalement et ils s'intéressaient aux conséquences des signalements, par exemple l'ouverture d'un dossier pour une prestation continue de services ou le placement. Conclusion : Les articles utilisant des données de l'ECI ont obtenu des scores positifs pour la plupart des indicateurs de qualité. Dans leurs analyses les plus récentes, les chercheurs se sont concentrés sur les catégories de maltraitance insuffisamment étudiées jusqu'ici (exposition à la violence conjugale, négligence et

  6. Legal instruments for groundwater protection. A systematic analysis of EU law and German federal law and state law; Rechtliche Instrumente des Grundwasserschutzes. Eine systematische Analyse des EG-, Bundes- und Landesrechts

    Energy Technology Data Exchange (ETDEWEB)

    Kotulla, M.

    1999-07-01

    In Germany, the groundwater quality is endangered by a great variety of anthropogenic activities. Although it is widely accepted that the situation calls for quick action and implementation of legal provisions for efficient, nationwide protection of this essential natural resource, the legislature so far remained disappointingly inactive. This is why the author of the study presented in this book examines existing German federal and state law as well as EU law in order to reveal the possibilities offered by those bodies of law. The author analyses the many, splintered legal provisions under public law that are applicable today in Germany in absence of a proper code of environmental law, for their capability of being applied for protection of the groundwater. The legal instruments are identified and evaluated for the given purpose, and approaches for harmonisation or maybe optimisation are elaborated. (orig./CB) [German] Das Grundwasser in der Bundesrepublik Deutschland ist von einer Vielzahl zivilisatorischer Aktivitaeten bedroht. Strategien fuer einen prinzipiell flaechendeckend wirksamen Schutz dieser Naturressource werden zwar mittlerweile allenthalben gefordert, zeigen bislang aber nicht die erhoffte Wirkung. Vor diesem Hintergrund untersucht der Autor in dieser Studie die rechtlichen Moeglichkeiten, welche die bundesdeutsche Rechtsordnung unter Einbeziehung des einschlaegigen EG-Rechts zum Schutz des Grundwassers bereithaelt. Er analysiert primaer das in den letzten dreieinhalb Jahrzehnten zu einem unueberschaubaren Konglomerat angewachsene oeffentlich-rechtliche Umweltschutzregelwerk auf seine grundwasserschuetzende Eignung. Es gilt insbesondere, die diffus und querschnittartig ueber die verschiedensten Rechtsbereiche vertreuten Instrumentarien zu ermitteln und zu bewerten sowie - wo erforderlich - zu harmonisieren oder gar zu optimieren. (orig.)

  7. Phylogénie des monogènes basée sur une analyse de parcimonie des caractères de l'ultrastructure de la spermiogenèse et des spermatozoïdes incluant les résultats récents

    Directory of Open Access Journals (Sweden)

    JUSTINE J-L.

    1993-01-01

    Full Text Available Les caractères de la spermiogenèse et du spermatozoïde ont été utilisés pour une analyse de parcimonie des Monogènes avec le programme PAUP. Les données utilisées comprennent la matrice proposée dans une analyse précédente (JUSTINE, 1991, Int. J. Parasitol. 21: 821-838 et les données récemment publiées. Une matrice comprenant 27 taxons et 22 caractères est proposée, mais comme certains de ces taxons sont redondants ou mal définis (le spermatozoïde est connu mais la spermiogenèse n'est pas décrite, l'analyse de parcimonie n'a porté que sur 15 taxons (dont les Digenea considérés comme outgroup et les Polyopisthocotylea considérés comme un seul taxon. Un arbre de consensus a été calculé et a une longueur de 32 pas et un indice de confiance de 0,750. Les Polyopisthocotylea et les Monopisthocotylea sont chacun définis sur la base de synapomorphies, mais il n'existe pas de synapomorphie pour les Monogenea. A l'intérieur des Monopisthocotylea, plusieurs groupes sont définis. Un groupe comprend les Loimoidae et Monocotylidae, et apparaît comme groupe frère de tous les autres Monopisthocotylea. Une polytomie existe chez les autres Monopisthocotylea; les relations entre les Acanthocotylidae, Capsalidae et Gyrocotylidae ne sont pas résolues. Le groupe des Monoaxonematidea (monogènes à spermatozoïde uniflagellé apparaît monophylétique. A l'intérieur de ce groupe, Calceostoma, Cleithrarticus et Pseudodactylogyrus semblent unis en un monophylum.

  8. Présence de la publicité automobile dans la presse écrite belge : Analyse des quotidiens La Libre Belgique et Le Soir et des hebdomadaires Trends-Tendances et Le Vif-L’Express

    Directory of Open Access Journals (Sweden)

    Pierre Ozer

    2008-06-01

    Full Text Available De plus en plus, les aspects relatifs à l’environnement, et plus singulièrement au réchauffement climatique, prennent une place de choix dans le traitement de l’information par les médias. Bien sûr, le lien entre changement climatique et hivers sans neige, inondations dites exceptionnelles, ouragans dévastateurs ou canicules estivales s’invite en manchette des quotidiens et des hebdomadaires. Mais en plus, le concept de « global warming » revient systématiquement au devant de la scène car il est devenu un enjeu sociétal, environnemental et économique. Ainsi, la presse écrite interpelle-t-elle ses lecteurs à être conscients de cette problématique mais également acteurs dans ce domaine. La presse tend dès lors à nous interpeller, et c’est tout à son honneur, par rapport aux « bonnes pratiques » pour freiner notre débauche énergétique et propose des alternatives, le plus souvent peu contraignantes. Souvent, le choix d’une automobile « propre » apparaît comme une alternative. Mais, par rapport à l’automobile, la presse écrite est-elle cohérente avec le discours qu’elle pose sur papier et l’acte qu’elle promeut au travers des publicités qu’elle autorise de publier ? L’objectif de ce papier est dès lors d’apporter une réponse aux questions suivantes : 1] Quelle est la place de la publicité pour les automobiles dans la presse écrite ; 2] Quelles sont les émissions promues dans ces publicités par rapport aux objectifs à atteindre ; 3] Quelles pourraient être les solutions à cette problématique. Une analyse minutieuse des publicités pour les automobiles a été réalisée durant l’année 2006 dans quatre médias de la presse écrite belge francophone. Il ressort de cet examen que les publicités vantent des véhicules automobiles qui, du point de vue émissions de CO2/km, sont d’un autre âge et sont clairement en contradiction avec les valeurs prônées dans les articles de

  9. Analysis of structural heterogeneities on drilled cores: a reservoir modeling oriented methodology; Analyse des heterogeneites structurales sur carottes: une methodologie axee vers la modelisation des reservoirs

    Energy Technology Data Exchange (ETDEWEB)

    Cortes, P.; Petit, J.P. [Montpellier-2 Univ., Lab. de Geophysique, Tectonique et Sedimentologie, UMR CNRS 5573, 34 (France); Guy, L. [ELF Aquitaine Production, 64 - Pau (France); Thiry-Bastien, Ph. [Lyon-1 Univ., 69 (France)

    1999-07-01

    The characterization of structural heterogeneities of reservoirs is of prime importance for hydrocarbons recovery. A methodology is presented which allows to compare the dynamic behaviour of fractured reservoirs and the observation of microstructures on drilled cores or surface reservoir analogues. (J.S.)

  10. Gas Well Testing Analysis Using Finite-Difference Models and Optimization Techniques Analyse d'essais de puits de gaz par des modèles utilisant la méthode des différences finies et par des techniques d'optimisation

    Directory of Open Access Journals (Sweden)

    Darderes E. A.

    2006-11-01

    paramètres à partir d'essais de puits de gaz. Une des plus performantes est l'analyse du régime pseudo-permanent pour lequel on trouve, sur un graphique semi-logarithmique, une relation linéaire entre la pseudo-pression d'un gaz réel et le temps. Une autre méthode est l'ajustement à des courbes types. Les deux méthodes présentent l'inconvénient de ne pouvoir être rigoureusement appliquées qu'à des cas spécifiques. Cet article expose une méthode générale permettant d'analyser les données des essais de puits par ajustement automatisé des courbes types. Elle est basée sur le meilleur accord d'un modèle numérique avec les données obtenues dans les essais de puits de gaz grâce à des techniques d'optimisation. Le modèle numérique fournit la solution d'une équation différentielle à dérivées partielles du 2e ordre et fortement non linéaire qui régit le flux radial des gaz réels vers un puits de production. L'équation différentielle est résolue par la méthode des différences finies en tenant compte des variations des propriétés des gaz avec la pression. Pour simuler n'importe quel type d'essais de puits de gaz, on impose des conditions initiales et aux limites appropriées. On minimise les différences résiduelles entre les pressions réelles mesurées pendant l'essai et les pressions calculées par la méthode des moindres carrés. On utilise deux techniques d'optimisation pour obtenir la meilleure estimation des paramètres qui minimisent la somme des carrés des résidus : la méthode monovariante de Fibonacci [1] et la méthode polyvariante de Marquardt [1, 2]. On applique ce mode opératoire à des essais de puits menés à un débit constant et à deux débits constants. Les résultats numériques concordent très bien avec les données des essais de puits.

  11. IRE (Institut National des Radioelements) site in Belgium. Report of in situ measurements and analyses performed for the RTBF

    International Nuclear Information System (INIS)

    2010-05-01

    This document reports various analyses performed within the frame of the preparation and filming of a TV documentary on the Belgium National Institute of Radio-elements. It reports gamma radiation measurements performed at the vicinity of the institute, discusses the possible origin of its increase at the vicinity of the institute, analyses of sludge samples coming from a wastewater treatment works, and analyses of milk, cabbage, mosses and sediments collected by residents

  12. Comparative genomics analyses revealed two virulent Listeria monocytogenes strains isolated from ready-to-eat food.

    Science.gov (United States)

    Lim, Shu Yong; Yap, Kien-Pong; Thong, Kwai Lin

    2016-01-01

    Listeria monocytogenes is an important foodborne pathogen that causes considerable morbidity in humans with high mortality rates. In this study, we have sequenced the genomes and performed comparative genomics analyses on two strains, LM115 and LM41, isolated from ready-to-eat food in Malaysia. The genome size of LM115 and LM41 was 2,959,041 and 2,963,111 bp, respectively. These two strains shared approximately 90% homologous genes. Comparative genomics and phylogenomic analyses revealed that LM115 and LM41 were more closely related to the reference strains F2365 and EGD-e, respectively. Our virulence profiling indicated a total of 31 virulence genes shared by both analysed strains. These shared genes included those that encode for internalins and L. monocytogenes pathogenicity island 1 (LIPI-1). Both the Malaysian L. monocytogenes strains also harboured several genes associated with stress tolerance to counter the adverse conditions. Seven antibiotic and efflux pump related genes which may confer resistance against lincomycin, erythromycin, fosfomycin, quinolone, tetracycline, and penicillin, and macrolides were identified in the genomes of both strains. Whole genome sequencing and comparative genomics analyses revealed two virulent L. monocytogenes strains isolated from ready-to-eat foods in Malaysia. The identification of strains with pathogenic, persistent, and antibiotic resistant potentials from minimally processed food warrant close attention from both healthcare and food industry.

  13. La réforme foncière au Vietnam : Analyse des jeux d'acteurs et du processus de transformation des institutions aux échelons central et provincial

    OpenAIRE

    Mellac , Marie; Fortunel , Frederic; Dan Tran , Dac

    2010-01-01

    rapport scientifique; Une des particularités du foncier vietnamien réside dans l'existence d'un « état zéro » des institutions foncières, que l'on peut dater approximativement au début des années 1980, à partir duquel l'ensemble des institutions a été mis en place. Cet « état zéro » des institutions ne signifie bien entendu pas l'absence d'héritages : les institutions qui émergent aujourd'hui portent la trace de chacune des périodes passées. C'est le cas par exemple de la multiplicité des ins...

  14. Theoretical study of the electronic structure of f-element complexes by quantum chemical methods; Analyse de la structure electronique des complexes contenant des elements F par des methodes de la chimie quantique

    Energy Technology Data Exchange (ETDEWEB)

    Vetere, V

    2002-09-15

    This thesis is related to comparative studies of the chemical properties of molecular complexes containing lanthanide or actinide trivalent cations, in the context of the nuclear waste disposal. More precisely, our aim was a quantum chemical analysis of the metal-ligand bonding in such species. Various theoretical approaches were compared, for the inclusion of correlation (density functional theory, multiconfigurational methods) and of relativistic effects (relativistic scalar and 2-component Hamiltonians, relativistic pseudopotentials). The performance of these methods were checked by comparing computed structural properties to published experimental data, on small model systems: lanthanide and actinide tri-halides and on X{sub 3}M-L species (X=F, Cl; M=La, Nd, U; L = NH{sub 3}, acetonitrile, CO). We have thus shown the good performance of density functionals combined with a quasi-relativistic method, as well as of gradient-corrected functionals associated with relativistic pseudopotentials. In contrast, functionals including some part of exact exchange are less reliable to reproduce experimental trends, and we have given a possible explanation for this result . Then, a detailed analysis of the bonding has allowed us to interpret the discrepancies observed in the structural properties of uranium and lanthanides complexes, based on a covalent contribution to the bonding, in the case of uranium(III), which does not exist in the lanthanide(III) homologues. Finally, we have examined more sizeable systems, closer to experimental species, to analyse the influence of the coordination number, of the counter-ions and of the oxidation state of uranium, on the metal-ligand bonding. (author)

  15. Modèles et méthodologies d’analyse des compétences. Le double éclairage des pratiques et des recherches de Hajjar et Baubion-Broye

    Directory of Open Access Journals (Sweden)

    Jacques Leplat

    2005-11-01

    Full Text Available Le thème des compétences est d’actualité et de nombreuses disciplines se sentent concernées par son étude, notamment différentes spécialités de la psychologie, de l’ergonomie et de la sociologie. Octares témoigne de cet intérêt puisqu’il a déjà édité deux ouvrages sur ce thème : Leplat, J. et de Montmollin, M. (eds. (2001. Les compétences en ergonomie. Recueil de textes. Dupray, A., Guitton, C. & Monchatre, S. (eds.. (2003. Réfléchir la compétence. Approches sociologiques, juridiques, éco...

  16. The spectrographic analysis of inorganic impurities in heavy water; Analyse spectrographique des impuretes minerales dans l'eau lourde

    Energy Technology Data Exchange (ETDEWEB)

    Artaud, J; Normand, J [Commissariat a l' Energie Atomique, Service d' Analyses et de Recherches Chimiques Appliquees, Saclay (France). Centre d' Etudes Nucleaires; Vie, R [Commissariat a l' Energie Atomique, Service d' Etude de Traitement des Combustibles Irradies, Saclay (France). Centre d' Etudes Nucleaires

    1961-07-01

    Inorganic impurities in heavy water are determined by two spectrographic methods. First is described the copper-spark method which is sensitive and directly applicable, and is particular useful because of the absence of a support. Secondly the graphite impregnation method is given; this is used when the first method is not applicable (determination of copper) and for the alkali metals. For the usual elements, the sensitivity of the copper spark method is of the order of 0,1 {mu}g/ml whereas for the graphite impregnation method the sensitivity is only 0,3 {mu}g/ml. (author) [French] Les impuretes minerales dans l'eau lourde sont dosees au moyen de deux methodes spectrographiques. On decrit en premier lieu la methode 'copper spark' sensible directement applicable, et particulierement favorable du fait de l'absence de matrice. En second lieu, on decrit la methode d'impregnation du graphite, utilisee lorsque la methode precedente tombe en defaut (recherche du cuivre) et pour les alcalins. Avec la methode 'copper spark' nous obtenons pour les elements courants, des sensibilites de l'ordre de 0,1 {mu}g/ml, alors qu'elles ne sont que de 0,3 {mu}g/ml pour les alcalins doses a l'arc sur graphite impregne. (auteur)

  17. Comparative metagenomic and metatranscriptomic analyses of microbial communities in acid mine drainage.

    Science.gov (United States)

    Chen, Lin-xing; Hu, Min; Huang, Li-nan; Hua, Zheng-shuang; Kuang, Jia-liang; Li, Sheng-jin; Shu, Wen-sheng

    2015-07-01

    The microbial communities in acid mine drainage have been extensively studied to reveal their roles in acid generation and adaption to this environment. Lacking, however, are integrated community- and organism-wide comparative gene transcriptional analyses that could reveal the response and adaptation mechanisms of these extraordinary microorganisms to different environmental conditions. In this study, comparative metagenomics and metatranscriptomics were performed on microbial assemblages collected from four geochemically distinct acid mine drainage (AMD) sites. Taxonomic analysis uncovered unexpectedly high microbial biodiversity of these extremely acidophilic communities, and the abundant taxa of Acidithiobacillus, Leptospirillum and Acidiphilium exhibited high transcriptional activities. Community-wide comparative analyses clearly showed that the AMD microorganisms adapted to the different environmental conditions via regulating the expression of genes involved in multiple in situ functional activities, including low-pH adaptation, carbon, nitrogen and phosphate assimilation, energy generation, environmental stress resistance, and other functions. Organism-wide comparative analyses of the active taxa revealed environment-dependent gene transcriptional profiles, especially the distinct strategies used by Acidithiobacillus ferrivorans and Leptospirillum ferrodiazotrophum in nutrients assimilation and energy generation for survival under different conditions. Overall, these findings demonstrate that the gene transcriptional profiles of AMD microorganisms are closely related to the site physiochemical characteristics, providing clues into the microbial response and adaptation mechanisms in the oligotrophic, extremely acidic environments.

  18. Les nouvelles perspectives d'analyse spatiale des nuisances sonores. Le projet SIGAUR (Système d'Information Géographique et Acoustique URbaine

    Directory of Open Access Journals (Sweden)

    Erwan Quesseveur

    1999-06-01

    Full Text Available Ce rapport présente un projet de recherche sur l’intégration d’une couche d’information de nuisances acoustiques dans un système d’information géographique.Après un développement sur l’état de la pollution et des moyens aujourd’hui en vigueur pour la combattre, on va montrer les nouvelles perspectives offertes pour l’analyse spatiale du bruit. En confrontant cette nuisance aux enjeux du territoire, elle peut devenir un véritable critère de décision en aménagement du territoire.Ce projet résulte d’une collaboration entre le Centre Scientifique et Technique du Bâtiment C.S.T.B. et l’équipe " S.I.G. " de l'Institut de Géographie Alpine (IGA

  19. Approche comparée de quelques évolutions de la gestion du risque en France à travers l’organisation des agences

    Directory of Open Access Journals (Sweden)

    Hubert Philippe

    2000-09-01

    Full Text Available L’organisation nationale en matière d’évaluation et de gestion des risques est en cours de modifications depuis quelques années. Organisée par une loi en 1998, la création d’agences pour la sécurité sanitaire des aliments, des produits de santé et de l’environnement a marqué une étape. D’autres domaines sont en cours de réorganisation comme la sûreté nucléaire et la radioprotection. La mise en oeuvre de la directive SEVESO II peut aussi influer sur la gestion des installations industrielles classées dites « SEVESO ». Des « événements » comme la crise de la vache folle ou celle du sang contaminé ont joué un rôle dans les évolutions, mais l’émergence de nouveaux principes de gestion des risques au sein de la communauté internationale a aussi influé fortement sur les choix faits et les discussions. Le travail présenté ici est un travail préliminaire, qui visait à identifier les grandes lignes des réponses apportées dans les différents domaines à des questions comme celles du rôle des différentes institutions en matière d’évaluation et de gestion. L’approche comparative suivie ici est trop globale pour que tous les éléments de chaque système réglementaire soit décrit et certains aspects sont simplifiés. En revanche, ce type de comparaison met en lumière des contrastes notables quant aux solutions trouvées pour articuler le travail d’évaluation des risques et les prises de décision relevant des autorités.

  20. Contribution to the study of influences in emission spectrography on solutions. Application to a general analysis method for stainless steels (1961); Contribution a l'etude des influences en spectographie d'emission sur solution. Application a une methode generale d'analyse des aciers inoxydables (1961)

    Energy Technology Data Exchange (ETDEWEB)

    Baudin, G [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1961-11-15

    In order to establish a general method of analysis of stainless steels, by means of spark spectroscopy on solutions, a systematic study has been made of the factors involved. The variations in acidity of the solutions, or in the ratio of concentrations of two acids at constant pH, lead to a displacement of the calibration curve. Simple relations have been established between the concentration of the extraneous elements, and the effects produced, for the constituents Fe, Ti, Ni, Cr, Mn; a general method using abacus is proposed for steels containing only these elements. The interactions in the case of the elements Mo, Nb, Ta, W, were more complex, so that the simultaneous separation was studied with the help of ion-exchange resins. A general method of analysis is proposed for stainless steels. (author) [French] En vue d'etablir une methode generale d'analyse des aciers inoxydables par spectrographie d'etincelles sur solution, on a effectue une etude systematique des influences. Les variations de l'acidite des solutions ou du rapport des concentrations de deux acides a pH constant, entrainent un deplacement des courbes d'etalonnage. On a etabli des relations simples entre la teneur des tiers elements et les effets produits pour les constituants Fe, Ti, Ni, Cr, Mn; une methode generale avec abaques est proposee pour les aciers contenant ces seuls elements. Les influences dans le cas des elements Mo, Nb, Ta, W etant plus complexes, on eut a etudier la separation simultanee a l'aide de resines echangeuses d'ions. On propose une methode generale d'analyse des aciers inoxydables. (auteur)

  1. Comparative survey of dynamic analyses of free-piston Stirling engines

    Science.gov (United States)

    Kankam, M. D.; Rauch, J. S.

    1991-01-01

    Reported dynamics analyses for evaluating the steady-state response and stability of free-piston Stirling engine (FPSE) systems are compared. Various analytical approaches are discussed to provide guidance on their salient features. Recommendations are made in the recommendations remarks for an approach which captures most of the inherent properties of the engine. Such an approach has the potential for yielding results which will closely match practical FPSE-load systems.

  2. COMPARATIVE BIOMECHANICAL ANALYSES OF SQUAT JUMP WITHOUT AND WITH FLEXION IN KNEE JOINT

    Directory of Open Access Journals (Sweden)

    Saša Bubanj

    2009-11-01

    Full Text Available In sports hall of Faculty of sports and physical education in Niš, student demon- strated technique of squat jump – without and with flexion in knee joint. Elements of technique were recorded by using one digital video camera in sagital plane. By using comparative kinematics analyses, there were establish differences in values of kinema- tics parametres of different body segments. Bigger elevation of body centre of gravity was ascertain at bounce without flexion in knee joint.

  3. Influence des melanges complexes organiques sur le sort des dioxines et furanes: Implications dans le developpement de facteurs de caracterisation en analyse du cycle de vie

    Science.gov (United States)

    Taing, Eric

    The environmental fate of dioxins and furans, or polychlorodibenzo-p-dioxins and -furans (PCDD/Fs), leaching from wood poles treated with pentachlorophenol (PCP) oil is modified by the presence of oil. Interactions between co-contaminants, which also exist for other pollutants within the mixtures, were shown in the specific context of risk analysis, but have never been taken into account for the generic context of life cycle assessment (LCA). This decision-making tool relies on characterization factors (CF) to estimate the potential impacts of an emitted amount of a pollutant in different impact categories such as aquatic ecotoxicity and human toxicity. For these two impact categories, CFs are calculated from a cause-effect chain that models the environmental fate, exposure and effects of the pollutant (represented by a matrix of fate FF, exposure XF and effect EF, respectively), meaning that a modification of PCDD/Fs fate induces a change in PCDD/Fs CFs. The research question is therefore as follows: In life cycle impact assessment (LCIA), to what extent would the potential impacts of PCDD/Fs on aquatic ecotoxicity and human toxicity change when taking into account the influence of a complex organic mixture on PCDD/Fs fate?. Thus, the main objective is to develop CFs of PCDD/Fs when their fate is influenced by PCP oil and compare them with the CFs of PCDD/Fs without oil for the aquatic ecotoxicity and human toxicity impact categories. A mathematic approach is established to determine the new environmental distribution of PCDD/Fs in the presence of oil and a new FF' matrix is calculated from this new distribution to obtain new CFs' integrating oil influence. FF' and CF' are then compared to FF and CF of PCDD/Fs without the oil. Finally, potential (eco)toxic impacts of the PCDD/F Canadian emissions are calculated with the new CFs' of PCDD/Fs in presence of oil. By only focusing on the results for an emission into air, freshwater and natural soil on a continental

  4. Analyse de facteurs déterminants de la substitution par des médicaments génériques en Suisse

    OpenAIRE

    Decollogny, A.

    2012-01-01

    Cadre de l'étude La part des dépenses de santé dans les budgets des pays occidentaux est importante et tend à croître depuis plusieurs décennies. Une des conséquences, notamment pour la Suisse, est une augmentation régulière des primes d'assurance maladie, dont l'impopularité incite les responsables politiques à trouver des stratégies de frein à la croissance des coûts de la santé. Les médicaments, qui contribuent notablement à l'augmentation de ces coûts, constituent l'une des cibles clas...

  5. Velocity Analysis Using Nonhyperbolic Move-Out in Anisotropic Media of Arbitrary Symmetry: Synthetic and Field Data Studies Analyse de vitesse par correction non hyperbolique des indicatrices dans les milieux anisotropes de symétrie arbitraire : étude sur des données synthétiques et réelles

    Directory of Open Access Journals (Sweden)

    Tabti H.

    2006-12-01

    une analyse de cohérence le long d'indicatrices non hyperboliques (i. e. comprenant les longs déports source-récepteur permettant d'évaluer les paramètres effectifs suivis d'un processus de Dix pour l'estimation des paramètres d'intervalle. D'autre part, Sayers et Ebrom (1997 ont proposé de leur côté une autre expression non hyperbolique du temps de trajet ainsi que les expressions de Dix correspondantes valables pour les milieux tabulaires présentant des anisotropies azimutales. La méthode a été testée sur des modèles synthétiques homogènes présentant des anisotropies variées. Nous proposons ici une généralisation de la méthode présentée par Alkhalifah, applicable à des milieux tabulaires d'anisotropie quelconque mais modérée (i. e. avec des degrés d'anisotropie pouvant aller jusqu'à environ 20 %. La paramétrisation de la vitesse est une extension naturelle de celle utilisée par l'auteur précédent. Elle s'exprime à l'aide des paramètres généralisés de Thomsen (1986 développés par Mensch et Rasolofosaon (1997. Dans un premier temps, la méthode est appliquée sur des données synthétiques obtenues à partir d'un modèle à 6 couches présentant des anisotropies variées (à la fois le type et le degré. La robustesse de la méthode y est démontrée. En effet, tous les paramètres d'intervalle (ici Vnmo et la vitesse horizontale Vh sont estimés de façon satisfaisante (erreur < 2 %, à comparer aux degrés d'anisotropie qui varient de 15 à 20 % et ce pour tous les azimuts. La méthode est ensuite appliquée sur des données réelles de mer du Nord comprenant trois profils sismiques se croisant au niveau d'un puits.

  6. Comparative analyses of basal rate of metabolism in mammals: data selection does matter.

    Science.gov (United States)

    Genoud, Michel; Isler, Karin; Martin, Robert D

    2018-02-01

    Basal rate of metabolism (BMR) is a physiological parameter that should be measured under strictly defined experimental conditions. In comparative analyses among mammals BMR is widely used as an index of the intensity of the metabolic machinery or as a proxy for energy expenditure. Many databases with BMR values for mammals are available, but the criteria used to select metabolic data as BMR estimates have often varied and the potential effect of this variability has rarely been questioned. We provide a new, expanded BMR database reflecting compliance with standard criteria (resting, postabsorptive state; thermal neutrality; adult, non-reproductive status for females) and examine potential effects of differential selectivity on the results of comparative analyses. The database includes 1739 different entries for 817 species of mammals, compiled from the original sources. It provides information permitting assessment of the validity of each estimate and presents the value closest to a proper BMR for each entry. Using different selection criteria, several alternative data sets were extracted and used in comparative analyses of (i) the scaling of BMR to body mass and (ii) the relationship between brain mass and BMR. It was expected that results would be especially dependent on selection criteria with small sample sizes and with relatively weak relationships. Phylogenetically informed regression (phylogenetic generalized least squares, PGLS) was applied to the alternative data sets for several different clades (Mammalia, Eutheria, Metatheria, or individual orders). For Mammalia, a 'subsampling procedure' was also applied, in which random subsamples of different sample sizes were taken from each original data set and successively analysed. In each case, two data sets with identical sample size and species, but comprising BMR data with different degrees of reliability, were compared. Selection criteria had minor effects on scaling equations computed for large clades

  7. Sequencing, Characterization, and Comparative Analyses of the Plastome of Caragana rosea var. rosea

    Directory of Open Access Journals (Sweden)

    Mei Jiang

    2018-05-01

    Full Text Available To exploit the drought-resistant Caragana species, we performed a comparative study of the plastomes from four species: Caragana rosea, C. microphylla, C. kozlowii, and C. Korshinskii. The complete plastome sequence of the C. rosea was obtained using the next generation DNA sequencing technology. The genome is a circular structure of 133,122 bases and it lacks inverted repeat. It contains 111 unique genes, including 76 protein-coding, 30 tRNA, and four rRNA genes. Repeat analyses obtained 239, 244, 258, and 246 simple sequence repeats in C. rosea, C. microphylla, C. kozlowii, and C. korshinskii, respectively. Analyses of sequence divergence found two intergenic regions: trnI-CAU-ycf2 and trnN-GUU-ycf1, exhibiting a high degree of variations. Phylogenetic analyses showed that the four Caragana species belong to a monophyletic clade. Analyses of Ka/Ks ratios revealed that five genes: rpl16, rpl20, rps11, rps7, and ycf1 and several sites having undergone strong positive selection in the Caragana branch. The results lay the foundation for the development of molecular markers and the understanding of the evolutionary process for drought-resistant characteristics.

  8. 137 Analyse fréquentielle des évènements hydro-pluviométriques ...

    African Journals Online (AJOL)

    Utilisateur

    Frequentiel analyse of extreme hydropluviometric events iin the Sota basin of Benin. West Africa is one of the most vulnerable regions of the world to the climatic variability. According to the forecasts of the GIEC, some extreme phenomena will increase frequency and/or intensity in the XXIe century because of the evolution ...

  9. CrusView: a Java-based visualization platform for comparative genomics analyses in Brassicaceae species.

    Science.gov (United States)

    Chen, Hao; Wang, Xiangfeng

    2013-09-01

    In plants and animals, chromosomal breakage and fusion events based on conserved syntenic genomic blocks lead to conserved patterns of karyotype evolution among species of the same family. However, karyotype information has not been well utilized in genomic comparison studies. We present CrusView, a Java-based bioinformatic application utilizing Standard Widget Toolkit/Swing graphics libraries and a SQLite database for performing visualized analyses of comparative genomics data in Brassicaceae (crucifer) plants. Compared with similar software and databases, one of the unique features of CrusView is its integration of karyotype information when comparing two genomes. This feature allows users to perform karyotype-based genome assembly and karyotype-assisted genome synteny analyses with preset karyotype patterns of the Brassicaceae genomes. Additionally, CrusView is a local program, which gives its users high flexibility when analyzing unpublished genomes and allows users to upload self-defined genomic information so that they can visually study the associations between genome structural variations and genetic elements, including chromosomal rearrangements, genomic macrosynteny, gene families, high-frequency recombination sites, and tandem and segmental duplications between related species. This tool will greatly facilitate karyotype, chromosome, and genome evolution studies using visualized comparative genomics approaches in Brassicaceae species. CrusView is freely available at http://www.cmbb.arizona.edu/CrusView/.

  10. ANALYSE DES MODES DE GESTION DES ENTREPRISES ...

    African Journals Online (AJOL)

    Administrateur

    va définir, jusqu'à nos jours, les modes de gestion de l'entreprise théâtrale publique en Algérie. Les émeutes de 1988 avaient mis fin au socialisme et avaient, pour l'occasion, ouvert la porte au multipartisme et à l'économie de marché. Une crise économique s'en était suivie mettant l'économie nationale en grande difficulté ...

  11. ANALYSE DES MODES DE GESTION DES ENTREPRISES ...

    African Journals Online (AJOL)

    Administrateur

    culturel, considéré de plus en plus comme enjeu politique et les questions liées à ..... recrutement et les modes de rémunération y sont aussi précisés. Comme le TNA ..... équipement stratégique qui met la société au centre de son intérêt par.

  12. L’infarctus du myocarde du jeune adulte -Analyse rétrospective des cas colligés au CHU de Dakar

    Directory of Open Access Journals (Sweden)

    Nobila Valentin Yameogo

    2010-09-01

    Full Text Available Les données relatives à l’infarctus du myocarde chez le jeune adulte sont rares en Afrique noir. Nous rapportons une série rétrospective de 14 cas d’infarctus du myocarde chez l’adulte jeune noir africain. Pour analyser les caractéristiques épidémiologiques, cliniques, électriques, échographiques, biologiques, thérapeutiques et évolutives de l’infarctus aigu du myocarde chez le jeune adulte nous avons étudié de manière rétrospective les dossiers médicaux d’une série consécutive des patients admis entre Janvier 2003 et Décembre 2008 pour prise en charge d’infarctus aigu du myocarde. Quatre-vingt quatre (84 cas d’infarctus du myocarde ont été pris en charge durant la période d’étude ,14 patients (16,6% avaient un âge inférieur ou égal à 40 ans. L’âge moyen était de 34 +ou-5ans (extrêmes 27ans et 40 ans. Les facteurs de risque cardio-vasculaire étaient dominés par le sexe masculin (n=11, la dyslipidémie (n=7 et le tabagisme par cigarette (n=6. La contraception orale était absente chez le 1/3 des patients. Le délai moyen d’admission était tardif (15 plus ou moins 4 heures. L’IDM était antérieur dans la moitié des cas. L’acide acétylsalicylique, les inhibiteurs de l’enzyme de conversion Les bétabloquants et les statines étaient les médicaments les plus prescrits. La thrombolyse et l’angioplastie étaient respectivement réalisées chez 3 patients et 0 patient. 4 cas d’insuffisance cardiaque, 2 cas de bloc atrio-ventriculaire complet et 1 cas de décès étaient les principales complications. L’infarctus du myocarde concerne également le sujet jeune noir africain. Les facteurs de risque sont essentiellement représentés par le sexe, la dyslipidémie, le tabagisme et la contraception orale.

  13. La précarité : une catégorie d’analyse pertinente des enjeux de la norme d’emploi et des situations sociales « d’entre-deux »

    Directory of Open Access Journals (Sweden)

    Maryse Bresson

    2011-04-01

    Full Text Available Le présent article propose de prolonger le débat sur « La précarité » commencé dans la livraison de SociologieS mise en ligne le 27 septembre 2010. Il met en perspective les analyses d’Henri Eckert et Mircea Vultur, et propose une grille d’analyse de la précarité ou plus exactement, ici, des emplois dits « atypiques ». L’auteure invite à distinguer d’une part, les représentations sociales et les ressentis « subjectifs » des individus ; d’autre part, les processus économiques et sociaux associés aux transformations du marché du travail, afin de mieux articuler ensuite ces deux dimensions, en insistant sur l’enjeu de la norme d’emploi, et sur l’idée « d’entre-deux » proposée comme clé de lecture de la précarité.Precariousness: a pertinent analysis of the standard of employment issues and of "in-between" social situationsThis paper proposes to extend the debate on "Precariousness" started in SociologieS online on September 27, 2010. It puts into perspective analyses of Henry Eckert and Mircea Vultur, and offers an analysis of precariousness, or more precisely, here, jobs as "atypical". The author invites to distinguish, on the one hand, social representations and how individualsfeel subjectively the precariousness; on the other hand, economic and social processes associated to changes in the labour market, in order to better articulate these two dimensions, with particular emphasis on the issue of the standard of employment, and on the idea of "in-between" proposed as a key to reading the precariousness.¿Es la precariedad un concepto pertinente en lo que concierne la problemática del empleo y des situaciones sociales ambiguas?Este artículo es la continuación del debate sobe la precariedad publicado en la red en Sociologies el 27 septiembre de 2010. Pone en perspectiva los análisis de Henri Eckert y de Mircea Vultur y presenta un panel de análisis de la precariedad en particular de los

  14. Comparative chloroplast genomics: Analyses including new sequencesfrom the angiosperms Nuphar advena and Ranunculus macranthus

    Energy Technology Data Exchange (ETDEWEB)

    Raubeso, Linda A.; Peery, Rhiannon; Chumley, Timothy W.; Dziubek,Chris; Fourcade, H. Matthew; Boore, Jeffrey L.; Jansen, Robert K.

    2007-03-01

    The number of completely sequenced plastid genomes available is growing rapidly. This new array of sequences presents new opportunities to perform comparative analyses. In comparative studies, it is most useful to compare across wide phylogenetic spans and, within angiosperms, to include representatives from basally diverging lineages such as the new genomes reported here: Nuphar advena (from a basal-most lineage) and Ranunculus macranthus (from the basal group of eudicots). We report these two new plastid genome sequences and make comparisons (within angiosperms, seed plants, or all photosynthetic lineages) to evaluate features such as the status of ycf15 and ycf68 as protein coding genes, the distribution of simple sequence repeats (SSRs) and longer dispersed repeats (SDR), and patterns of nucleotide composition.

  15. Analyse des mortalités chez les ovins à Nioka (Ituri, Haut-Zaïre

    Directory of Open Access Journals (Sweden)

    Dibanzilua, M.

    1995-01-01

    Full Text Available Mortalities Analyses by the Ovines in Nioka (Ituri-Zaire. An analysis of the deaths of "fatty-tailed sheep" bred at the Nioka Research Centre has shown that the deaths of animals between January 89 and 31 st December 1993, were due to the wormy diarrhoea (43.8 %, the new-born deaths (19.4 % and to unknown causes (14.28 %. The authors recommend a means to fight and to bring under control.

  16. Comparative genome analyses of Serratia marcescens FS14 reveals its high antagonistic potential.

    Directory of Open Access Journals (Sweden)

    Pengpeng Li

    Full Text Available S. marcescens FS14 was isolated from an Atractylodes macrocephala Koidz plant that was infected by Fusarium oxysporum and showed symptoms of root rot. With the completion of the genome sequence of FS14, the first comprehensive comparative-genomic analysis of the Serratia genus was performed. Pan-genome and COG analyses showed that the majority of the conserved core genes are involved in basic cellular functions, while genomic factors such as prophages contribute considerably to genome diversity. Additionally, a Type I restriction-modification system, a Type III secretion system and tellurium resistance genes are found in only some Serratia species. Comparative analysis further identified that S. marcescens FS14 possesses multiple mechanisms for antagonism against other microorganisms, including the production of prodigiosin, bacteriocins, and multi-antibiotic resistant determinants as well as chitinases. The presence of two evolutionarily distinct Type VI secretion systems (T6SSs in FS14 may provide further competitive advantages for FS14 against other microbes. To our knowledge, this is the first report of comparative analysis on T6SSs in the genus, which identifies four types of T6SSs in Serratia spp.. Competition bioassays of FS14 against the vital plant pathogenic bacterium Ralstonia solanacearum and fungi Fusarium oxysporum and Sclerotinia sclerotiorum were performed to support our genomic analyses, in which FS14 demonstrated high antagonistic activities against both bacterial and fungal phytopathogens.

  17. Comparative genome analyses of Serratia marcescens FS14 reveals its high antagonistic potential.

    Science.gov (United States)

    Li, Pengpeng; Kwok, Amy H Y; Jiang, Jingwei; Ran, Tingting; Xu, Dongqing; Wang, Weiwu; Leung, Frederick C

    2015-01-01

    S. marcescens FS14 was isolated from an Atractylodes macrocephala Koidz plant that was infected by Fusarium oxysporum and showed symptoms of root rot. With the completion of the genome sequence of FS14, the first comprehensive comparative-genomic analysis of the Serratia genus was performed. Pan-genome and COG analyses showed that the majority of the conserved core genes are involved in basic cellular functions, while genomic factors such as prophages contribute considerably to genome diversity. Additionally, a Type I restriction-modification system, a Type III secretion system and tellurium resistance genes are found in only some Serratia species. Comparative analysis further identified that S. marcescens FS14 possesses multiple mechanisms for antagonism against other microorganisms, including the production of prodigiosin, bacteriocins, and multi-antibiotic resistant determinants as well as chitinases. The presence of two evolutionarily distinct Type VI secretion systems (T6SSs) in FS14 may provide further competitive advantages for FS14 against other microbes. To our knowledge, this is the first report of comparative analysis on T6SSs in the genus, which identifies four types of T6SSs in Serratia spp.. Competition bioassays of FS14 against the vital plant pathogenic bacterium Ralstonia solanacearum and fungi Fusarium oxysporum and Sclerotinia sclerotiorum were performed to support our genomic analyses, in which FS14 demonstrated high antagonistic activities against both bacterial and fungal phytopathogens.

  18. Comparative Genome Analyses of Serratia marcescens FS14 Reveals Its High Antagonistic Potential

    Science.gov (United States)

    Li, Pengpeng; Kwok, Amy H. Y.; Jiang, Jingwei; Ran, Tingting; Xu, Dongqing; Wang, Weiwu; Leung, Frederick C.

    2015-01-01

    S. marcescens FS14 was isolated from an Atractylodes macrocephala Koidz plant that was infected by Fusarium oxysporum and showed symptoms of root rot. With the completion of the genome sequence of FS14, the first comprehensive comparative-genomic analysis of the Serratia genus was performed. Pan-genome and COG analyses showed that the majority of the conserved core genes are involved in basic cellular functions, while genomic factors such as prophages contribute considerably to genome diversity. Additionally, a Type I restriction-modification system, a Type III secretion system and tellurium resistance genes are found in only some Serratia species. Comparative analysis further identified that S. marcescens FS14 possesses multiple mechanisms for antagonism against other microorganisms, including the production of prodigiosin, bacteriocins, and multi-antibiotic resistant determinants as well as chitinases. The presence of two evolutionarily distinct Type VI secretion systems (T6SSs) in FS14 may provide further competitive advantages for FS14 against other microbes. To our knowledge, this is the first report of comparative analysis on T6SSs in the genus, which identifies four types of T6SSs in Serratia spp.. Competition bioassays of FS14 against the vital plant pathogenic bacterium Ralstonia solanacearum and fungi Fusarium oxysporum and Sclerotinia sclerotiorum were performed to support our genomic analyses, in which FS14 demonstrated high antagonistic activities against both bacterial and fungal phytopathogens. PMID:25856195

  19. Comparative Phenotypical and Molecular Analyses of Arabidopsis Grown under Fluorescent and LED Light

    Directory of Open Access Journals (Sweden)

    Franka Seiler

    2017-06-01

    Full Text Available Comparative analyses of phenotypic and molecular traits of Arabidopsis thaliana grown under standardised conditions is still a challenge using climatic devices supplied with common light sources. These are in most cases fluorescent lights, which have several disadvantages such as heat production at higher light intensities, an invariable spectral output, and relatively rapid “ageing”. This results in non-desired variations of growth conditions and lowers the comparability of data acquired over extended time periods. In this study, we investigated the growth behaviour of Arabidopsis Col0 under different light conditions, applying fluorescent compared to LED lamps, and we conducted physiological as well as gene expression analyses. By changing the spectral composition and/or light intensity of LEDs we can clearly influence the growth behaviour of Arabidopsis and thereby study phenotypic attributes under very specific light conditions that are stable and reproducible, which is not necessarily given for fluorescent lamps. By using LED lights, we can also roughly mimic the sun light emission spectrum, enabling us to study plant growth in a more natural-like light set-up. We observed distinct growth behaviour under the different light regimes which was reflected by physiological properties of the plants. In conclusion, LEDs provide variable emission spectra for studying plant growth under defined, stable light conditions.

  20. CoNekT: an open-source framework for comparative genomic and transcriptomic network analyses.

    Science.gov (United States)

    Proost, Sebastian; Mutwil, Marek

    2018-05-01

    The recent accumulation of gene expression data in the form of RNA sequencing creates unprecedented opportunities to study gene regulation and function. Furthermore, comparative analysis of the expression data from multiple species can elucidate which functional gene modules are conserved across species, allowing the study of the evolution of these modules. However, performing such comparative analyses on raw data is not feasible for many biologists. Here, we present CoNekT (Co-expression Network Toolkit), an open source web server, that contains user-friendly tools and interactive visualizations for comparative analyses of gene expression data and co-expression networks. These tools allow analysis and cross-species comparison of (i) gene expression profiles; (ii) co-expression networks; (iii) co-expressed clusters involved in specific biological processes; (iv) tissue-specific gene expression; and (v) expression profiles of gene families. To demonstrate these features, we constructed CoNekT-Plants for green alga, seed plants and flowering plants (Picea abies, Chlamydomonas reinhardtii, Vitis vinifera, Arabidopsis thaliana, Oryza sativa, Zea mays and Solanum lycopersicum) and thus provide a web-tool with the broadest available collection of plant phyla. CoNekT-Plants is freely available from http://conekt.plant.tools, while the CoNekT source code and documentation can be found at https://github.molgen.mpg.de/proost/CoNekT/.

  1. THE GOAL OF VALUE-BASED MEDICINE ANALYSES: COMPARABILITY. THE CASE FOR NEOVASCULAR MACULAR DEGENERATION

    Science.gov (United States)

    Brown, Gary C.; Brown, Melissa M.; Brown, Heidi C.; Kindermann, Sylvia; Sharma, Sanjay

    2007-01-01

    Purpose To evaluate the comparability of articles in the peer-reviewed literature assessing the (1) patient value and (2) cost-utility (cost-effectiveness) associated with interventions for neovascular age-related macular degeneration (ARMD). Methods A search was performed in the National Library of Medicine database of 16 million peer-reviewed articles using the key words cost-utility, cost-effectiveness, value, verteporfin, pegaptanib, laser photocoagulation, ranibizumab, and therapy. All articles that used an outcome of quality-adjusted life-years (QALYs) were studied in regard to (1) percent improvement in quality of life, (2) utility methodology, (3) utility respondents, (4) types of costs included (eg, direct healthcare, direct nonhealthcare, indirect), (5) cost bases (eg, Medicare, National Health Service in the United Kingdom), and (6) study cost perspective (eg, government, societal, third-party insurer). To qualify as a value-based medicine analysis, the patient value had to be measured using the outcome of the QALYs conferred by respective interventions. As with value-based medicine analyses, patient-based time tradeoff utility analysis had to be utilized, patient utility respondents were necessary, and direct medical costs were used. Results Among 21 cost-utility analyses performed on interventions for neovascular macular degeneration, 15 (71%) met value-based medicine criteria. The 6 others (29%) were not comparable owing to (1) varying utility methodology, (2) varying utility respondents, (3) differing costs utilized, (4) differing cost bases, and (5) varying study perspectives. Among value-based medicine studies, laser photocoagulation confers a 4.4% value gain (improvement in quality of life) for the treatment of classic subfoveal choroidal neovascularization. Intravitreal pegaptanib confers a 5.9% value gain (improvement in quality of life) for classic, minimally classic, and occult subfoveal choroidal neovascularization, and photodynamic therapy

  2. The goal of value-based medicine analyses: comparability. The case for neovascular macular degeneration.

    Science.gov (United States)

    Brown, Gary C; Brown, Melissa M; Brown, Heidi C; Kindermann, Sylvia; Sharma, Sanjay

    2007-01-01

    To evaluate the comparability of articles in the peer-reviewed literature assessing the (1) patient value and (2) cost-utility (cost-effectiveness) associated with interventions for neovascular age-related macular degeneration (ARMD). A search was performed in the National Library of Medicine database of 16 million peer-reviewed articles using the key words cost-utility, cost-effectiveness, value, verteporfin, pegaptanib, laser photocoagulation, ranibizumab, and therapy. All articles that used an outcome of quality-adjusted life-years (QALYs) were studied in regard to (1) percent improvement in quality of life, (2) utility methodology, (3) utility respondents, (4) types of costs included (eg, direct healthcare, direct nonhealthcare, indirect), (5) cost bases (eg, Medicare, National Health Service in the United Kingdom), and (6) study cost perspective (eg, government, societal, third-party insurer). To qualify as a value-based medicine analysis, the patient value had to be measured using the outcome of the QALYs conferred by respective interventions. As with value-based medicine analyses, patient-based time tradeoff utility analysis had to be utilized, patient utility respondents were necessary, and direct medical costs were used. Among 21 cost-utility analyses performed on interventions for neovascular macular degeneration, 15 (71%) met value-based medicine criteria. The 6 others (29%) were not comparable owing to (1) varying utility methodology, (2) varying utility respondents, (3) differing costs utilized, (4) differing cost bases, and (5) varying study perspectives. Among value-based medicine studies, laser photocoagulation confers a 4.4% value gain (improvement in quality of life) for the treatment of classic subfoveal choroidal neovascularization. Intravitreal pegaptanib confers a 5.9% value gain (improvement in quality of life) for classic, minimally classic, and occult subfoveal choroidal neovascularization, and photodynamic therapy with verteporfin confers

  3. Analyse und Bewertung von Naturgefahren als Grundlage für ein nachhaltiges Naturgefahrenmanagement in Gebirgssystemen SO-Kasachstans am Beispiel des Ile-Alatau

    OpenAIRE

    Yegorov, Alexandr

    2007-01-01

    Den Fragen der Erarbeitung des Naturgefahrenmanagements in Gebirgsystemen SO-Kasachstans und in den Ländern des Zentralasiens insgesamt wurde bisher keine gebührende Aufmerksamkeit zuteil. Die Naturkatastrophen der letzten Jahrzehnte sowie die Erfahrung mit Maßnahmen zum Schutz des Ile-Alatau vor Naturgefahren haben gezeigt, dass die Lösung dieser Probleme für die weitere nachhaltige Entwicklung dieser Region von erstrangiger Bedeutung ist. In dieser Arbeit wurde vom Autor umfangreiches Ma...

  4. Le fonds d'équité au Sénégal : analyse des mécanismes de la ...

    African Journals Online (AJOL)

    entreprises, salariés), la couverture des gros risques pour rendre plus attractives ... La couverture du risque maladie des indigents est une politique publique .... Face à ces inégalités dans la protection sociale, le Sénégal adopte une stratégie ..... recrutement des assistants techniques régionaux chargés de faciliter ce ...

  5. Comparative transcriptome analyses indicate molecular homology of zebrafish swimbladder and mammalian lung.

    Directory of Open Access Journals (Sweden)

    Weiling Zheng

    Full Text Available The fish swimbladder is a unique organ in vertebrate evolution and it functions for regulating buoyancy in most teleost species. It has long been postulated as a homolog of the tetrapod lung, but the molecular evidence is scarce. In order to understand the molecular function of swimbladder as well as its relationship with lungs in tetrapods, transcriptomic analyses of zebrafish swimbladder were carried out by RNA-seq. Gene ontology classification showed that genes in cytoskeleton and endoplasmic reticulum were enriched in the swimbladder. Further analyses depicted gene sets and pathways closely related to cytoskeleton constitution and regulation, cell adhesion, and extracellular matrix. Several prominent transcription factor genes in the swimbladder including hoxc4a, hoxc6a, hoxc8a and foxf1 were identified and their expressions in developing swimbladder during embryogenesis were confirmed. By comparison of enriched transcripts in the swimbladder with those in human and mouse lungs, we established the resemblance of transcriptome of the zebrafish swimbladder and mammalian lungs. Based on the transcriptomic data of zebrafish swimbladder, the predominant functions of swimbladder are in its epithelial and muscular tissues. Our comparative analyses also provide molecular evidence of the relatedness of the fish swimbladder and mammalian lung.

  6. Comparative multivariate analyses of transient otoacoustic emissions and distorsion products in normal and impaired hearing.

    Science.gov (United States)

    Stamate, Mirela Cristina; Todor, Nicolae; Cosgarea, Marcel

    2015-01-01

    The clinical utility of otoacoustic emissions as a noninvasive objective test of cochlear function has been long studied. Both transient otoacoustic emissions and distorsion products can be used to identify hearing loss, but to what extent they can be used as predictors for hearing loss is still debated. Most studies agree that multivariate analyses have better test performances than univariate analyses. The aim of the study was to determine transient otoacoustic emissions and distorsion products performance in identifying normal and impaired hearing loss, using the pure tone audiogram as a gold standard procedure and different multivariate statistical approaches. The study included 105 adult subjects with normal hearing and hearing loss who underwent the same test battery: pure-tone audiometry, tympanometry, otoacoustic emission tests. We chose to use the logistic regression as a multivariate statistical technique. Three logistic regression models were developed to characterize the relations between different risk factors (age, sex, tinnitus, demographic features, cochlear status defined by otoacoustic emissions) and hearing status defined by pure-tone audiometry. The multivariate analyses allow the calculation of the logistic score, which is a combination of the inputs, weighted by coefficients, calculated within the analyses. The accuracy of each model was assessed using receiver operating characteristics curve analysis. We used the logistic score to generate receivers operating curves and to estimate the areas under the curves in order to compare different multivariate analyses. We compared the performance of each otoacoustic emission (transient, distorsion product) using three different multivariate analyses for each ear, when multi-frequency gold standards were used. We demonstrated that all multivariate analyses provided high values of the area under the curve proving the performance of the otoacoustic emissions. Each otoacoustic emission test presented high

  7. Genome-based comparative analyses of Antarctic and temperate species of Paenibacillus.

    Directory of Open Access Journals (Sweden)

    Melissa Dsouza

    Full Text Available Antarctic soils represent a unique environment characterised by extremes of temperature, salinity, elevated UV radiation, low nutrient and low water content. Despite the harshness of this environment, members of 15 bacterial phyla have been identified in soils of the Ross Sea Region (RSR. However, the survival mechanisms and ecological roles of these phyla are largely unknown. The aim of this study was to investigate whether strains of Paenibacillus darwinianus owe their resilience to substantial genomic changes. For this, genome-based comparative analyses were performed on three P. darwinianus strains, isolated from gamma-irradiated RSR soils, together with nine temperate, soil-dwelling Paenibacillus spp. The genome of each strain was sequenced to over 1,000-fold coverage, then assembled into contigs totalling approximately 3 Mbp per genome. Based on the occurrence of essential, single-copy genes, genome completeness was estimated at approximately 88%. Genome analysis revealed between 3,043-3,091 protein-coding sequences (CDSs, primarily associated with two-component systems, sigma factors, transporters, sporulation and genes induced by cold-shock, oxidative and osmotic stresses. These comparative analyses provide an insight into the metabolic potential of P. darwinianus, revealing potential adaptive mechanisms for survival in Antarctic soils. However, a large proportion of these mechanisms were also identified in temperate Paenibacillus spp., suggesting that these mechanisms are beneficial for growth and survival in a range of soil environments. These analyses have also revealed that the P. darwinianus genomes contain significantly fewer CDSs and have a lower paralogous content. Notwithstanding the incompleteness of the assemblies, the large differences in genome sizes, determined by the number of genes in paralogous clusters and the CDS content, are indicative of genome content scaling. Finally, these sequences are a resource for further

  8. Comparative Genomic and Transcriptional Analyses of CRISPR Systems Across the Genus Pyrobaculum

    Directory of Open Access Journals (Sweden)

    David L Bernick

    2012-07-01

    Full Text Available Within the domain Archaea, the CRISPR immune system appears to be nearly ubiquitous based on computational genome analyses. Initial studies in bacteria demonstrated that the CRISPR system targets invading plasmid and viral DNA. Recent experiments in the model archaeon Pyrococcus furiosus uncovered a novel RNA-targeting variant of the CRISPR system potentially unique to archaea. Because our understanding of CRISPR system evolution in other archaea is limited, we have taken a comparative genomic and transcriptomic view of the CRISPR arrays across six diverse species within the crenarchaeal genus Pyrobaculum. We present transcriptional data from each of four species in the genus (P. aerophilum, P. islandicum, P. calidifontis, P. arsenaticum, analyzing mature CRISPR-associated small RNA abundance from over 20 arrays. Within the genus, there is remarkable conservation of CRISPR array structure, as well as unique features that are have not been studied in other archaeal systems. These unique features include: a nearly invariant CRISPR promoter, conservation of direct repeat families, the 5' polarity of CRISPR-associated small RNA abundance, and a novel CRISPR-specific association with homologues of nurA and herA. These analyses provide a genus-level evolutionary perspective on archaeal CRISPR systems, broadening our understanding beyond existing non-comparative model systems.

  9. Parametric analyses of summative scores may lead to conflicting inferences when comparing groups: A simulation study.

    Science.gov (United States)

    Khan, Asaduzzaman; Chien, Chi-Wen; Bagraith, Karl S

    2015-04-01

    To investigate whether using a parametric statistic in comparing groups leads to different conclusions when using summative scores from rating scales compared with using their corresponding Rasch-based measures. A Monte Carlo simulation study was designed to examine between-group differences in the change scores derived from summative scores from rating scales, and those derived from their corresponding Rasch-based measures, using 1-way analysis of variance. The degree of inconsistency between the 2 scoring approaches (i.e. summative and Rasch-based) was examined, using varying sample sizes, scale difficulties and person ability conditions. This simulation study revealed scaling artefacts that could arise from using summative scores rather than Rasch-based measures for determining the changes between groups. The group differences in the change scores were statistically significant for summative scores under all test conditions and sample size scenarios. However, none of the group differences in the change scores were significant when using the corresponding Rasch-based measures. This study raises questions about the validity of the inference on group differences of summative score changes in parametric analyses. Moreover, it provides a rationale for the use of Rasch-based measures, which can allow valid parametric analyses of rating scale data.

  10. Comparative Genomics and Transcriptomics Analyses Reveal Divergent Lifestyle Features of Nematode Endoparasitic Fungus Hirsutella minnesotensis

    Science.gov (United States)

    Lai, Yiling; Liu, Keke; Zhang, Xinyu; Zhang, Xiaoling; Li, Kuan; Wang, Niuniu; Shu, Chi; Wu, Yunpeng; Wang, Chengshu; Bushley, Kathryn E.; Xiang, Meichun; Liu, Xingzhong

    2014-01-01

    Hirsutella minnesotensis [Ophiocordycipitaceae (Hypocreales, Ascomycota)] is a dominant endoparasitic fungus by using conidia that adhere to and penetrate the secondary stage juveniles of soybean cyst nematode. Its genome was de novo sequenced and compared with five entomopathogenic fungi in the Hypocreales and three nematode-trapping fungi in the Orbiliales (Ascomycota). The genome of H. minnesotensis is 51.4 Mb and encodes 12,702 genes enriched with transposable elements up to 32%. Phylogenomic analysis revealed that H. minnesotensis was diverged from entomopathogenic fungi in Hypocreales. Genome of H. minnesotensis is similar to those of entomopathogenic fungi to have fewer genes encoding lectins for adhesion and glycoside hydrolases for cellulose degradation, but is different from those of nematode-trapping fungi to possess more genes for protein degradation, signal transduction, and secondary metabolism. Those results indicate that H. minnesotensis has evolved different mechanism for nematode endoparasitism compared with nematode-trapping fungi. Transcriptomics analyses for the time-scale parasitism revealed the upregulations of lectins, secreted proteases and the genes for biosynthesis of secondary metabolites that could be putatively involved in host surface adhesion, cuticle degradation, and host manipulation. Genome and transcriptome analyses provided comprehensive understanding of the evolution and lifestyle of nematode endoparasitism. PMID:25359922

  11. Analysis of the German market for voluntary carbon offsetting; Analyse des deutschen Marktes zur freiwilligen Kompensation von Treibhausgasemissionen

    Energy Technology Data Exchange (ETDEWEB)

    Kind, Christian; Duwe, Sebastian; Taenzler, Dennis; Reuster, Lena [adelphi research gGmbH, Berlin (Germany); Kleemann, Max; Krebs, Jan-Marten [sustainable AG, Muenchen (Germany)

    2010-12-15

    In the past years the market for voluntary carbon offsetting has developed rapidly. Certificates sold on this market originate partly from the compliance market, i.e. from projects of the Clean Development Mechanism and the Joint Implementation. Mostly, however, certificates stem from projects of the voluntary carbon market. Voluntary carbon offsetting can serve as another mechanism to efficiently prevent emissions, while at the same time achieving co-benefits. Very little is known however of the exact state of the voluntary carbon market, e.g. factors like business volume, market actors, origin of certificates or the efficacy of the voluntary market. Analyses of the market on the global market for voluntary offsetting do exist (ENDS, Hamilton et al. 2007, 2008, 2009); however they do not allow any conclusions for the market situation in Germany. This study aims at closing this gap. From the end of 2009 until the beginning of 2010 adelphi and sustainable interviewed providers of offset services, intermediaries, certifiers and consumers like businesses and public institutions on their activities in the voluntary carbon offset market in Germany. (orig.)

  12. Analyse économique de la structure des coûts de production apicole au Cameroun

    Directory of Open Access Journals (Sweden)

    Muluh, GA.

    2008-01-01

    Full Text Available Economic Analysis of the Bee Farming Costs Structure in Cameroon. Beekeeping is spreading in Cameroon, and contributes to the sustainable management of the non timber forest products. This study presents the structure of the bee farms production factors in the North-West of the aforesaid country. The assumption is that there would be a significant difference in the production costs components between the types of bee-farms in the North-West of Cameroon. The data collected in 2005 related to the operation of the exploitations, the cost factors and income. The analyses were made using Excel and SPSS software, and the principal results are the following. Bee farming returns to scale are decreasing in the North-West of Cameroon. The bee farms of this zone invest more in the capital factor. Their follow-up is very insufficient, whereas all can maximize profit. Although there is a significant difference of the total fixed costs of production between the traditional bee exploitations and the semi modern ones, there is no difference in variable costs, nor in total cost of production between them. The setting-up of an apiculture policy which insists on extension services close to the bee-farmers is essential for the rise of this sub sector.

  13. Measurement and analysis of high energy radiation through activation detectors. Application in dosimetry; Sur la mesure et l'analyse des rayonnements de haute energie par detecteurs a activation. Application a la dosimetrie

    Energy Technology Data Exchange (ETDEWEB)

    Sklavenitis, L. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1967-10-15

    This work is concerned with the possibility of measurement and analysis of radiation fluences within objects of small volume submitted to a high energy proton beam. The first part, consecrated to the establishment of a method of analysis, comprises a detailed study of the radiation nature and energy spectra as well as of the various dosimetry methods. In order to select a group of detectors, high energy nuclear reactions were systematically studied and for some of them cross sections were measured or calculated: for example the cross section of the reaction {sup 11}B (p,n) {sup 11}C between 150 and 3000 MeV and of the reaction {sup 34}S (p,2pn) {sup 32}P between 50 and 3000 MeV. The second part is relative to the application of the fore-mentioned analysis to radiation within a tissue equivalent phantom irradiated by 3 GeV protons. This analysis is sufficiently detailed to allow the reconstitution of the absorbed doses, the dose equivalent and, contingent on a better knowledge of the dose due to heavy particles, the quality factors. It allowed also to follow the evolution of the various dosimetric data as a function of the depth inside the phantom and to verify calculations already done by other researchers. The comparison of the measured doses and the corresponding detector activities revealed the possibility that some detectors could give directly the absorbed dose, or even the dose equivalent, by a simple activity measurement. (author) [French] Le travail porte sur la possibilite de mesure et d'analyse, a l'aide de detecteurs a activation, des fluences de rayonnements a l'interieur d'un objet de petit volume soumis a un faisceau de protons de tres haute energie. La premiere partie, consacree a la mise au point de la methode d'analyse des fluences, comporte une etude detaillee de la nature des rayonnements et de leurs spectres energetiques ainsi que des differentes methodes de dosimetrie. Pour arriver au choix d'un groupe de

  14. Measurement and analysis of high energy radiation through activation detectors. Application in dosimetry; Sur la mesure et l'analyse des rayonnements de haute energie par detecteurs a activation. Application a la dosimetrie

    Energy Technology Data Exchange (ETDEWEB)

    Sklavenitis, L [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1967-10-15

    This work is concerned with the possibility of measurement and analysis of radiation fluences within objects of small volume submitted to a high energy proton beam. The first part, consecrated to the establishment of a method of analysis, comprises a detailed study of the radiation nature and energy spectra as well as of the various dosimetry methods. In order to select a group of detectors, high energy nuclear reactions were systematically studied and for some of them cross sections were measured or calculated: for example the cross section of the reaction {sup 11}B (p,n) {sup 11}C between 150 and 3000 MeV and of the reaction {sup 34}S (p,2pn) {sup 32}P between 50 and 3000 MeV. The second part is relative to the application of the fore-mentioned analysis to radiation within a tissue equivalent phantom irradiated by 3 GeV protons. This analysis is sufficiently detailed to allow the reconstitution of the absorbed doses, the dose equivalent and, contingent on a better knowledge of the dose due to heavy particles, the quality factors. It allowed also to follow the evolution of the various dosimetric data as a function of the depth inside the phantom and to verify calculations already done by other researchers. The comparison of the measured doses and the corresponding detector activities revealed the possibility that some detectors could give directly the absorbed dose, or even the dose equivalent, by a simple activity measurement. (author) [French] Le travail porte sur la possibilite de mesure et d'analyse, a l'aide de detecteurs a activation, des fluences de rayonnements a l'interieur d'un objet de petit volume soumis a un faisceau de protons de tres haute energie. La premiere partie, consacree a la mise au point de la methode d'analyse des fluences, comporte une etude detaillee de la nature des rayonnements et de leurs spectres energetiques ainsi que des differentes methodes de dosimetrie. Pour arriver au choix d'un groupe de detecteurs, une etude systematique des

  15. Comparative Analyses of Zebrafish Anxiety-Like Behavior Using Conflict-Based Novelty Tests.

    Science.gov (United States)

    Kysil, Elana V; Meshalkina, Darya A; Frick, Erin E; Echevarria, David J; Rosemberg, Denis B; Maximino, Caio; Lima, Monica Gomes; Abreu, Murilo S; Giacomini, Ana C; Barcellos, Leonardo J G; Song, Cai; Kalueff, Allan V

    2017-06-01

    Modeling of stress and anxiety in adult zebrafish (Danio rerio) is increasingly utilized in neuroscience research and central nervous system (CNS) drug discovery. Representing the most commonly used zebrafish anxiety models, the novel tank test (NTT) focuses on zebrafish diving in response to potentially threatening stimuli, whereas the light-dark test (LDT) is based on fish scototaxis (innate preference for dark vs. bright areas). Here, we systematically evaluate the utility of these two tests, combining meta-analyses of published literature with comparative in vivo behavioral and whole-body endocrine (cortisol) testing. Overall, the NTT and LDT behaviors demonstrate a generally good cross-test correlation in vivo, whereas meta-analyses of published literature show that both tests have similar sensitivity to zebrafish anxiety-like states. Finally, NTT evokes higher levels of cortisol, likely representing a more stressful procedure than LDT. Collectively, our study reappraises NTT and LDT for studying anxiety-like states in zebrafish, and emphasizes their developing utility for neurobehavioral research. These findings can help optimize drug screening procedures by choosing more appropriate models for testing anxiolytic or anxiogenic drugs.

  16. Comparing of Normal Stress Distribution in Static and Dynamic Soil-Structure Interaction Analyses

    International Nuclear Information System (INIS)

    Kholdebarin, Alireza; Massumi, Ali; Davoodi, Mohammad; Tabatabaiefar, Hamid Reza

    2008-01-01

    It is important to consider the vertical component of earthquake loading and inertia force in soil-structure interaction analyses. In most circumstances, design engineers are primarily concerned about the analysis of behavior of foundations subjected to earthquake-induced forces transmitted from the bedrock. In this research, a single rigid foundation with designated geometrical parameters located on sandy-clay soil has been modeled in FLAC software with Finite Different Method and subjected to three different vertical components of earthquake records. In these cases, it is important to evaluate effect of footing on underlying soil and to consider normal stress in soil with and without footing. The distribution of normal stress under the footing in static and dynamic states has been studied and compared. This Comparison indicated that, increasing in normal stress under the footing caused by vertical component of ground excitations, has decreased dynamic vertical settlement in comparison with static state

  17. Comparative multielement analyses of airborne particulate samples collected in various areas

    International Nuclear Information System (INIS)

    Mamuro, Tetsuo; Matsuda, Yatsuka; Mizohata, Akira

    1973-01-01

    In order to grasp the characteristic features of the air pollution by particulates in various areas in Japan, multielement analyses by instrumental neutron activation analysis and radioisotope energy dispersive X-ray fluorescence analysis were applied to 31 airborne particulate samples collected in 15 different areas, and the analytical results obtained were compared with one another. All the samples were collected by so-called ''10 micron cut'' samplers, the collection efficiency of which is considered to be 50% at 8μ and nearly zero beyond 10μ. Among the areas in question there are clean seaside areas, heavily industrialized areas, small cities along the Inland Sea or the Pacific Ocean around which industrialization is progressing, a small city having only a big iron work, an area famous for its ceramic industry and so on. The atmospheres over them were found to be quite different not only in pollution extent but also in pollution pattern. (auth.)

  18. Comparative analyses on dynamic performances of photovoltaic–thermal solar collectors integrated with phase change materials

    International Nuclear Information System (INIS)

    Su, Di; Jia, Yuting; Alva, Guruprasad; Liu, Lingkun; Fang, Guiyin

    2017-01-01

    Highlights: • The dynamic model of photovoltaic–thermal collector with phase change material was developed. • The performances of photovoltaic–thermal collector are performed comparative analyses. • The performances of photovoltaic–thermal collector with phase change material were evaluated. • Upper phase change material mode can improve performances of photovoltaic–thermal collector. - Abstract: The operating conditions (especially temperature) of photovoltaic–thermal solar collectors have significant influence on dynamic performance of the hybrid photovoltaic–thermal solar collectors. Only a small percentage of incoming solar radiation can be converted into electricity, and the rest is converted into heat. This heat leads to a decrease in efficiency of the photovoltaic module. In order to improve the performance of the hybrid photovoltaic–thermal solar collector, we performed comparative analyses on a hybrid photovoltaic–thermal solar collector integrated with phase change material. Electrical and thermal parameters like solar cell temperature, outlet temperature of air, electrical power, thermal power, electrical efficiency, thermal efficiency and overall efficiency are simulated and analyzed to evaluate the dynamic performance of the hybrid photovoltaic–thermal collector. It is found that the position of phase change material layer in the photovoltaic–thermal collector has a significant effect on the performance of the photovoltaic–thermal collector. The results indicate that upper phase change material mode in the photovoltaic–thermal collector can significantly improve the thermal and electrical performance of photovoltaic–thermal collector. It is found that overall efficiency of photovoltaic–thermal collector in ‘upper phase change material’ mode is 10.7% higher than that in ‘no phase change material’ mode. Further, for a photovoltaic–thermal collector with upper phase change material, it is verified that 3 cm

  19. A modeling approach to compare ΣPCB concentrations between congener-specific analyses

    Science.gov (United States)

    Gibson, Polly P.; Mills, Marc A.; Kraus, Johanna M.; Walters, David M.

    2017-01-01

    Changes in analytical methods over time pose problems for assessing long-term trends in environmental contamination by polychlorinated biphenyls (PCBs). Congener-specific analyses vary widely in the number and identity of the 209 distinct PCB chemical configurations (congeners) that are quantified, leading to inconsistencies among summed PCB concentrations (ΣPCB) reported by different studies. Here we present a modeling approach using linear regression to compare ΣPCB concentrations derived from different congener-specific analyses measuring different co-eluting groups. The approach can be used to develop a specific conversion model between any two sets of congener-specific analytical data from similar samples (similar matrix and geographic origin). We demonstrate the method by developing a conversion model for an example data set that includes data from two different analytical methods, a low resolution method quantifying 119 congeners and a high resolution method quantifying all 209 congeners. We used the model to show that the 119-congener set captured most (93%) of the total PCB concentration (i.e., Σ209PCB) in sediment and biological samples. ΣPCB concentrations estimated using the model closely matched measured values (mean relative percent difference = 9.6). General applications of the modeling approach include (a) generating comparable ΣPCB concentrations for samples that were analyzed for different congener sets; and (b) estimating the proportional contribution of different congener sets to ΣPCB. This approach may be especially valuable for enabling comparison of long-term remediation monitoring results even as analytical methods change over time. 

  20. Analyse comparative de pratiques d’animation d’une discussion à visée démocratique et philosophique vues sous l’angle de la temporalité

    OpenAIRE

    Pierrisnard, Christine

    2015-01-01

    Cette étude s’intéresse à la manière dont l’outil « Discussion à Visée Démocratique et Philosophique » (DVDP) est transformé par ses utilisateurs en instrument au fil des situations. L’analyse comparative des pratiques d’un animateur plutôt novice et d’un animateur expert fait apparaître trois éléments cruciaux de représentation temporelle de la situation de DVDP. Un empan temporel large, ancré dans le temps long pour le nécessaire recul de la pensée ; le kaïros, ancré dans l’immédiateté et l...

  1. Analyse des memdranes de déshydratation du melange eau t butanol par procede de pervaporation.

    Directory of Open Access Journals (Sweden)

    Mahacine Amrani

    2007-01-01

    Full Text Available The performance of commercially available polymeric membranes was investigated respect to the dehydration of binary mixtures of t-butanol and water by pervaporation process. The range of concentration investigated  CH2O  20 wt%   was selected according to industrial needs. Fluxes and selections were monitored as dehydratation proceeded, and the performances of both membranes were compared. In addition, the effect of temperature was investigated in the 60 to 100°C range, covering the pervaporation operating conditions. Increasing the operating temperature resulted, as expected, in larger water pervaporation fluxes for both membranes. For the range of the investigated conditions, water fluxes through the polymeric 2510 PERVAP membrane were found to be larger than those of the silica 2000 US membrane. The difference in performances becomes much more marked for higher temperatures.

  2. Life cycle assessment applied to wastewater treatment; Analyse de cycle de vie appliquee aux systemes de traitement des eaux usees

    Energy Technology Data Exchange (ETDEWEB)

    Renou, S.

    2006-01-15

    Nowadays, the environmental performances of wastewater treatment systems are not properly analyzed. Thus, the development of an exhaustive and reliable method is needed to help stakeholders to choose the best environmental solutions. Life cycle assessment (LCA) was selected as a starting point to answer this problem. LCA has been tested. This tool is essential to analyze the environmental performances of wastewater treatment systems. In order to fulfill our goal, the best compromise seems to be the association of LCA, to assess global impacts, with others methodologies, to assess local impacts. Finally, a software has been developed to compare urban sludge treatment and recovering process trains. Two impacts, energy and greenhouse effect, are currently included in. The software and its development steps are described and illustrated through two case studies. This tool has made LCA easier to apply and more useful to wastewater field stakeholders. (author)

  3. Automation on computers of the partial area method for the analysis of 's' neutron induced resonances. I. Without interference terms. (1962); Automatisation sur ordinateur de la methode des aires partielle dans l'analyse des resonances induites par les neutrons 's'. I. sans terme d'interference. (1962)

    Energy Technology Data Exchange (ETDEWEB)

    Bianchi, G; Corge, C R [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1962-07-01

    This report deals with numerical analysis of transmission resonances induced by 's' wave neutrons in time of flight experiments. The analysis method used is the partial area one. The only case treated here, in this first part, is the one when the interference term can be neglected. Programs and subroutines are thoroughly described, which determine from experimental raw data the resonant transmission, the partial areas, and the resonance parameters. (authors) [French] Le present rapport a pour objet l'analyse numerique sur ordinateur IBM 7090, des resonances dues aux neutrons 's' dans les experiences de transmission par temps de vol, la methode d'analyse utilisee etant la methode des aires partielles. Dans cette premiere partie, seul a ete envisage le cas ou le terme d'interference peut etre neglige. On y trouvera une description detaillee des programmes et sous programmes elabores pour determiner les transmissions resonantes avec leur trace, a partir des donnees experimentales brutes, les aires partielles afferentes ainsi que les parametres caracteristiques des resonances. (auteurs)

  4. Modelisation temporelle de la consommation electrique en analyse du cycle de vie appliquee au contexte des TIC

    Science.gov (United States)

    Maurice, Elsa

    Fossil fuels are a scarce energy resource. Since the industrial revolution, mankind uses and abuses of non-renewable energies. They are responsible for many environmental damages. The production of energy is one of the main challenges for a global sustainable development. In our society, we can witness an exponential increase of the usage of the systems of Information and Communication Technologies (ICT) such as Internet, phone calls, etc. The ICT development allows the creation and optimization of many smart systems, the pooling of services, and it also helps damping the climate change. However, because of their electric consumption, the ICT are also responsible for some green house gases (GHG) emissions: 3% in total. This fact gives them the willingness to change in order to limit their GHG emissions. In order to properly evaluate and optimize the ICT services, it is necessary to use some methods of evaluation that comply with the specificity of these systems. Currently, the methods used to evaluate the GHG emissions are not adapted to dynamic systems, which include the ICT systems. The variations of the production of electricity in a day or even a month are not yet taken into account. This problem is far from being restricted to the modelling of GHG emissions, it widens to the global variation in production and consumption of electricity. The Life Cycle Assessment (LCA) method grants useful and complete tools to analyse their environmental impacts, but, as with the GHG computation methods, it should be dynamically adapted. In the ICT framework, the first step to solve this LCA problem is to be able to model the variations in time of the electricity production. This master thesis introduces a new way to include the variation in time of the consumption and production of electricity in LCA methods. First, it generates an historical hourly database of the electricity production and import-export of three Canadian states: Alberta, Ontario and Quebec. Then it develops

  5. Interpretation of Bioassay Data; Interpretation des Donnees de l'Analyse d'Echantillons Biologiques; Interpretatsiya dannykh biologicheskikh issledovanij; Interpretacion de Datos Obtenidos por Bioanalisis

    Energy Technology Data Exchange (ETDEWEB)

    Dolphin, G. W.; Jackson, S. [Health Physics and Medical Division, Atomic Energy Research Establishment, Harwell, Berkshire (United Kingdom)

    1964-10-15

    routine surveillance of a group of personnel. The data available about metabolism of the radionuclide are used to evaluate an investigation level, namely, the urinary excretion rate corresponding to a chosen level of body content. It is important that measurements for routine surveillance should be made with maximum accuracy and carer fully recorded. These measurements may be used much later in making an assessment of .the chronically- acquired body content. A summary is presented of the human data available on metabolism and urinary excretion of tritium, caesium, uranium, strontium, radium and plutonium. (author) [French] Afin d'evaluer la dose de rayonnements a l'organe critique due a la contamination interne par un radionucleide, il faut mesurer la quantite du radionucleide dans le corps. Quand le radionucleide emet des rayons gamma ou X, ou des rayonnements beta donnant.naissance a un rayonnement de freinage convenable, on peut proceder a-desmesures directes de la charge corporelle de ce radionucleide dans un anthroporadiametre, mais lorsque le radionucleide n'emet pas de rayonnements convenables, on est oblige d'evaluer la charge corporelle d'apres les mesures de la quantite du radionucleide contenue dans les excreta, le sang, l'haleine ou des tampons provenant du nez ou de la bouche. Certaines etudes ont ete faites sur l'elimination urinaire des radionucleides, consideree comme un indice de la contamination interne, et l'analyse de l'urine est la forme la plus repandue de l'analyse d'echantillons biologiques. Cependant, le caractere fragmentaire des donnees de reference dont on dispose sur le metabolisme des radionucleides constitue toujours une faiblesse tres grave et il faut faire d'urgence beaucoup de travaux de recherche dans ce domaine. Dans cette etude, on a classe les differents modes de metabolisme des divers radionucleides en trois grandes categories. Le premier groupe comprend les radionucleides repartis dans l'ensemble du corps de facon assez uniforme. Le

  6. L’Hôpital's Analyse des infiniments petits an annotated translation with source material by Johann Bernoulli

    CERN Document Server

    Bradley, Robert E; Sandifer, C Edward

    2015-01-01

    This monograph is an annotated translation of what is considered to be the world’s first calculus textbook, originally published in French in 1696. That anonymously published textbook on differential calculus was based on lectures given to the Marquis de l’Hôpital in 1691-2 by the great Swiss mathematician, Johann Bernoulli. In the 1920s, a copy of Bernoulli’s lecture notes was discovered in a library in Basel, which presented the opportunity to compare Bernoulli’s notes, in Latin, to l’Hôpital’s text in French. The similarities are remarkable, but there is also much in l’Hôpital’s book that is original and innovative. This book offers the first English translation of Bernoulli's notes, along with the first faithful English translation of l’Hôpital’s text, complete with annotations and commentary. Additionally, a significant portion of the correspondence between l’Hôpital and Bernoulli has been included, also for the fi rst time in English translation. This translation will provide ...

  7. Automation on computer of the partial area method in the analysis of resonances induced by 'S' neutrons 2. with an interference term and extension of the method to the treatment of multi resonances (1963); Automatisation sur ordinateur de la methode des aires partielles dans l'analyse des resonances induites par les neutrons ''S''. 2, avec terme d'interference et extension de la methode au traitement des multiresonances (1963)

    Energy Technology Data Exchange (ETDEWEB)

    Bianchi, G; Corge, C R [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1963-07-01

    This report deals with the numerical analysis on an I.B.M. 7090 computer of transmission resonances induced by 's' wave neutrons in time of flight experiments. The analysis method used is the partial area one. In this second part the interference term is taken into account. Modifications have been made in the programs and subroutines described in the first part, to determine the resonant transmissions from experimental raw data, and the relating partial areas. Also programs and subroutines are thoroughly described, which estimate the resonance parameters. The field of the partial area method has been extended to cover the case where several resonances have to be treated simultaneously, provided they do not interfere. (authors) [French] Le pretent rapport a pour objet l'analyse numerique sur ordinateur I.B.M. 7090 des resonances dues aux neutrons ''s'' dans les experiences de transmission par temps de vol, la methode d'analyse utilisee etant la methode dea aires partielles. Dans cette deuxieme partie il a ete tenu compte du terme d'interference. On y trouvera une description des amenagements apportes aux programmes et sous-programmes decrits dans la premiere partie pour determiner les transmissions interfero-resonnantes a partir des donnees experimentales brutes et les aires partielles afferentes. Sont egalement decrits les programmes et sous-programmes necessaires au calcul des parametres caracteristiques des resonances. Le domaine d'application de la methode a ete etendu au traitement simultane de plusieurs resonances groupees n'interferant pas entre elles. (auteurs)

  8. Electron paramagnetic resonance study of radicals formed by radiolysis at 77 K of nitroalkanes and of their solutions in organic glasses. Chromatography analysis of radiolysis products of nitromethane in ethanol solution in a vitreous medium; Etude par resonance paramagnetique electronique des radicaux formes par radiolyse a 77 K des nitroalcanes et de leurs solutions dans les verres organiques analyse par chromatographie des produits de la radiolyse du nitromethane en solution dans l'ethanol en milieux vitreux

    Energy Technology Data Exchange (ETDEWEB)

    Rosilio, C [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1968-05-01

    With a view to explaining the formation of the final products resulting from the photolysis and the radiolysis of nitro-alkanes, we have attempted to identify the paramagnetic species formed as intermediates during the radiolysis. Our work has covered the structure and the reactivity of the radicals formed by 7 irradiation of the nitrogen containing derivatives at 77 K, and on the mechanism of formation and of disappearance of these radicals in the various matrices used. The radicals resulting from the removal of a hydrogen atom in the {alpha} position of the NO{sub 2} group, and the radicals resulting from addition reactions on the nitrogen group characterized by an unpaired electron on the nitrogen have been identified, either during the radiolysis of pure nitroalkanes, or during the radiolysis of nitro-alkanes in solution in organic glasses at 77 K. A study has been made of the conformation and the movements of radicals in the matrices, and the mechanism of formation of the observed radicals produced generally by the capture by the nitro-alkanes of primary radiolysis species. The nitro-alkanes in ethanol solution can behave as traps both for electrons and for free radicals. The study of the radiolysis of nitro-alkanes in solution in a polar ethanol glass has been completed with chemical analyses on the final radiolysis products; it has been possible to deduce the capture efficiency of trapped electrons and of free radicals by nitro-alkanes in ethanol. For this we have determined the radio-chemical yields of hydrogen, acetaldehyde and glycol as a function of the capture agent concentration, for the nitro-methane-ethanol system. A mechanism for the disappearance of the observed radicals is proposed. (author) [French] Dans le but d'expliquer la formation des produits finals formes au cours de la photolyse et la radiolyse des nitroalcanes, nous nous sommes proposes d'identifier les especes paramagnetiques se formant intermediairement au cours de la radiolyse. Notre

  9. Electron paramagnetic resonance study of radicals formed by radiolysis at 77 K of nitroalkanes and of their solutions in organic glasses. Chromatography analysis of radiolysis products of nitromethane in ethanol solution in a vitreous medium; Etude par resonance paramagnetique electronique des radicaux formes par radiolyse a 77 K des nitroalcanes et de leurs solutions dans les verres organiques analyse par chromatographie des produits de la radiolyse du nitromethane en solution dans l'ethanol en milieux vitreux

    Energy Technology Data Exchange (ETDEWEB)

    Rosilio, C. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1968-05-01

    With a view to explaining the formation of the final products resulting from the photolysis and the radiolysis of nitro-alkanes, we have attempted to identify the paramagnetic species formed as intermediates during the radiolysis. Our work has covered the structure and the reactivity of the radicals formed by 7 irradiation of the nitrogen containing derivatives at 77 K, and on the mechanism of formation and of disappearance of these radicals in the various matrices used. The radicals resulting from the removal of a hydrogen atom in the {alpha} position of the NO{sub 2} group, and the radicals resulting from addition reactions on the nitrogen group characterized by an unpaired electron on the nitrogen have been identified, either during the radiolysis of pure nitroalkanes, or during the radiolysis of nitro-alkanes in solution in organic glasses at 77 K. A study has been made of the conformation and the movements of radicals in the matrices, and the mechanism of formation of the observed radicals produced generally by the capture by the nitro-alkanes of primary radiolysis species. The nitro-alkanes in ethanol solution can behave as traps both for electrons and for free radicals. The study of the radiolysis of nitro-alkanes in solution in a polar ethanol glass has been completed with chemical analyses on the final radiolysis products; it has been possible to deduce the capture efficiency of trapped electrons and of free radicals by nitro-alkanes in ethanol. For this we have determined the radio-chemical yields of hydrogen, acetaldehyde and glycol as a function of the capture agent concentration, for the nitro-methane-ethanol system. A mechanism for the disappearance of the observed radicals is proposed. (author) [French] Dans le but d'expliquer la formation des produits finals formes au cours de la photolyse et la radiolyse des nitroalcanes, nous nous sommes proposes d'identifier les especes paramagnetiques se formant intermediairement au cours de la

  10. Comparative genomic analyses of nickel, cobalt and vitamin B12 utilization

    Directory of Open Access Journals (Sweden)

    Gelfand Mikhail S

    2009-02-01

    Full Text Available Abstract Background Nickel (Ni and cobalt (Co are trace elements required for a variety of biological processes. Ni is directly coordinated by proteins, whereas Co is mainly used as a component of vitamin B12. Although a number of Ni and Co-dependent enzymes have been characterized, systematic evolutionary analyses of utilization of these metals are limited. Results We carried out comparative genomic analyses to examine occurrence and evolutionary dynamics of the use of Ni and Co at the level of (i transport systems, and (ii metalloproteomes. Our data show that both metals are widely used in bacteria and archaea. Cbi/NikMNQO is the most common prokaryotic Ni/Co transporter, while Ni-dependent urease and Ni-Fe hydrogenase, and B12-dependent methionine synthase (MetH, ribonucleotide reductase and methylmalonyl-CoA mutase are the most widespread metalloproteins for Ni and Co, respectively. Occurrence of other metalloenzymes showed a mosaic distribution and a new B12-dependent protein family was predicted. Deltaproteobacteria and Methanosarcina generally have larger Ni- and Co-dependent proteomes. On the other hand, utilization of these two metals is limited in eukaryotes, and very few of these organisms utilize both of them. The Ni-utilizing eukaryotes are mostly fungi (except saccharomycotina and plants, whereas most B12-utilizing organisms are animals. The NiCoT transporter family is the most widespread eukaryotic Ni transporter, and eukaryotic urease and MetH are the most common Ni- and B12-dependent enzymes, respectively. Finally, investigation of environmental and other conditions and identity of organisms that show dependence on Ni or Co revealed that host-associated organisms (particularly obligate intracellular parasites and endosymbionts have a tendency for loss of Ni/Co utilization. Conclusion Our data provide information on the evolutionary dynamics of Ni and Co utilization and highlight widespread use of these metals in the three

  11. Correlation of Klebsiella pneumoniae comparative genetic analyses with virulence profiles in a murine respiratory disease model.

    Directory of Open Access Journals (Sweden)

    Ramy A Fodah

    Full Text Available Klebsiella pneumoniae is a bacterial pathogen of worldwide importance and a significant contributor to multiple disease presentations associated with both nosocomial and community acquired disease. ATCC 43816 is a well-studied K. pneumoniae strain which is capable of causing an acute respiratory disease in surrogate animal models. In this study, we performed sequencing of the ATCC 43816 genome to support future efforts characterizing genetic elements required for disease. Furthermore, we performed comparative genetic analyses to the previously sequenced genomes from NTUH-K2044 and MGH 78578 to gain an understanding of the conservation of known virulence determinants amongst the three strains. We found that ATCC 43816 and NTUH-K2044 both possess the known virulence determinant for yersiniabactin, as well as a Type 4 secretion system (T4SS, CRISPR system, and an acetonin catabolism locus, all absent from MGH 78578. While both NTUH-K2044 and MGH 78578 are clinical isolates, little is known about the disease potential of these strains in cell culture and animal models. Thus, we also performed functional analyses in the murine macrophage cell lines RAW264.7 and J774A.1 and found that MGH 78578 (K52 serotype was internalized at higher levels than ATCC 43816 (K2 and NTUH-K2044 (K1, consistent with previous characterization of the antiphagocytic properties of K1 and K2 serotype capsules. We also examined the three K. pneumoniae strains in a novel BALB/c respiratory disease model and found that ATCC 43816 and NTUH-K2044 are highly virulent (LD50<100 CFU while MGH 78578 is relatively avirulent.

  12. Essai d’une méthodologie d’analyse des données d’Internet sur un ordinateur

    OpenAIRE

    Géraldine Foin

    2017-01-01

    Dans l’étude de l’environnement numérique dans lequel les individus vivent et évoluent, des problèmes méthodologiques peuvent se poser pour les chercheurs en sciences humaines et sociales. Cet article s’interroge sur la compatibilité des outils classiques en sciences sociales pour l’étude des pratiques numériques sur un écran, celui de l’ordinateur. En effet, l’usage classique d’entretiens, de questionnaires ou d’observations ne suffit plus pour recueillir avec précision les données relatives...

  13. Comparative genome analyses reveal distinct structure in the saltwater crocodile MHC.

    Directory of Open Access Journals (Sweden)

    Weerachai Jaratlerdsiri

    Full Text Available The major histocompatibility complex (MHC is a dynamic genome region with an essential role in the adaptive immunity of vertebrates, especially antigen presentation. The MHC is generally divided into subregions (classes I, II and III containing genes of similar function across species, but with different gene number and organisation. Crocodylia (crocodilians are widely distributed and represent an evolutionary distinct group among higher vertebrates, but the genomic organisation of MHC within this lineage has been largely unexplored. Here, we studied the MHC region of the saltwater crocodile (Crocodylus porosus and compared it with that of other taxa. We characterised genomic clusters encompassing MHC class I and class II genes in the saltwater crocodile based on sequencing of bacterial artificial chromosomes. Six gene clusters spanning ∼452 kb were identified to contain nine MHC class I genes, six MHC class II genes, three TAP genes, and a TRIM gene. These MHC class I and class II genes were in separate scaffold regions and were greater in length (2-6 times longer than their counterparts in well-studied fowl B loci, suggesting that the compaction of avian MHC occurred after the crocodilian-avian split. Comparative analyses between the saltwater crocodile MHC and that from the alligator and gharial showed large syntenic areas (>80% identity with similar gene order. Comparisons with other vertebrates showed that the saltwater crocodile had MHC class I genes located along with TAP, consistent with birds studied. Linkage between MHC class I and TRIM39 observed in the saltwater crocodile resembled MHC in eutherians compared, but absent in avian MHC, suggesting that the saltwater crocodile MHC appears to have gene organisation intermediate between these two lineages. These observations suggest that the structure of the saltwater crocodile MHC, and other crocodilians, can help determine the MHC that was present in the ancestors of archosaurs.

  14. Analyse de l’effet du type de tâche sur l’évolution des connaissances à la suite d’un processus d’apprentissage collaboratif

    Directory of Open Access Journals (Sweden)

    Sabine Pohl

    2009-04-01

    Full Text Available L’article analyse l’effet du type de tâche sur le partage des connaissances à la suite d’un processus d’interaction dans un contexte d’apprentissage collaboratif. Cet apprentissage collaboratif est réalisé dans le cadre d’une formation universitaire. Deux types de tâches sont réalisés par les apprenants. Ils se distinguent selon que la solution nécessite ou non la confrontation de points de vue portant sur le champ conceptuel lié à l’apprentissage à réaliser. La méthode de collecte des données consiste en un entretien semi-directif. Les résultats montrent un effet du type de tâches sur l’évolution des connaissances partagées des apprenants.This longitudinal research analyses the effect of the type of task on the development of knowledge following an interaction process in a collaborative learning context. The framework for this collaborative learning is a university education. Two types of tasks are provided to the learners. They differ depending on whether or not the solution requires the comparison of points of view on the conceptual scope of what is to be learned. The data are collected through a semi-directive interview. The results show that the type of task has an effect on the development of shared knowledge.

  15. Absolute analysis of uranium isotopic concentrations with a gas ion source mass spectrometer; Analyses absolues des concentrations isotopiques de l'uranium par spectrometre de masse equipe d'une source a gaz

    Energy Technology Data Exchange (ETDEWEB)

    Chaussy, L.; Boyer, R. [Commissariat a l' Energie Atomique, Pierrelatte (France)

    1969-07-01

    Mass spectrometer with electronic bombardment ions source for routine uranium isotopic analysis are used like relative measurements apparatus. We show that such mass spectrometers can be used for absolute measurements with a very high sensitivity and precision which are ten times better than theses of thermo-ionic ions source mass spectrometer. We examine the causes of systematic errors and we give experimental data. In particular natural uranium sample used as reference give: U{sub 5} = 0.7202 {+-} 0.0005 atoms per cent; U{sub 4} = 0.00552 {+-} 0.0003 atoms per cent. The use of this method is justified for standards control. (authors) [French] Les spectrometres de masse a source par bombardement electronique pour l'analyse de l'uranium sous forme d'hexafluorure, sont utilises en routine comme des appareils de mesure relative. On montre que l'on peut utiliser de tels appareils pour effectuer des mesures absolues avec une excellente sensibilite et reproductibilite, dix fois superieure a celle des spectrometres a source thermoionique. On examine en detail les causes d'erreurs systematiques et on donne des resultats experimentaux. En particulier, l'analyse d'un echantillon d'uranium naturel donne: U{sub 5} = 0.7202 {+-} 0.0005 atomes pour cent; U{sub 4} = 0.00552 {+-} 0.0003 atomes pour cent. La technique de mesure est utile pour le controle d'etalons isotopiques. (auteurs)

  16. Promouvoir l'entrepreneuriat inclusif des jeunes et des femmes ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le projet vise à analyser la contribution réelle et potentielle de l'entrepreneuriat inclusif au bien-être des jeunes et des femmes en Côte d'Ivoire, au Burkina Faso et au Kenya. Après un état des lieux de la pratique de l'entrepreneuriat inclusif dans chacun des pays ciblés, l'équipe de recherche étudiera son incidence sur ...

  17. Characterization of Aeromonas hydrophila wound pathotypes by comparative genomic and functional analyses of virulence genes.

    Science.gov (United States)

    Grim, Christopher J; Kozlova, Elena V; Sha, Jian; Fitts, Eric C; van Lier, Christina J; Kirtley, Michelle L; Joseph, Sandeep J; Read, Timothy D; Burd, Eileen M; Tall, Ben D; Joseph, Sam W; Horneman, Amy J; Chopra, Ashok K; Shak, Joshua R

    2013-04-23

    Aeromonas hydrophila has increasingly been implicated as a virulent and antibiotic-resistant etiologic agent in various human diseases. In a previously published case report, we described a subject with a polymicrobial wound infection that included a persistent and aggressive strain of A. hydrophila (E1), as well as a more antibiotic-resistant strain of A. hydrophila (E2). To better understand the differences between pathogenic and environmental strains of A. hydrophila, we conducted comparative genomic and functional analyses of virulence-associated genes of these two wound isolates (E1 and E2), the environmental type strain A. hydrophila ATCC 7966(T), and four other isolates belonging to A. aquariorum, A. veronii, A. salmonicida, and A. caviae. Full-genome sequencing of strains E1 and E2 revealed extensive differences between the two and strain ATCC 7966(T). The more persistent wound infection strain, E1, harbored coding sequences for a cytotoxic enterotoxin (Act), a type 3 secretion system (T3SS), flagella, hemolysins, and a homolog of exotoxin A found in Pseudomonas aeruginosa. Corresponding phenotypic analyses with A. hydrophila ATCC 7966(T) and SSU as reference strains demonstrated the functionality of these virulence genes, with strain E1 displaying enhanced swimming and swarming motility, lateral flagella on electron microscopy, the presence of T3SS effector AexU, and enhanced lethality in a mouse model of Aeromonas infection. By combining sequence-based analysis and functional assays, we characterized an A. hydrophila pathotype, exemplified by strain E1, that exhibited increased virulence in a mouse model of infection, likely because of encapsulation, enhanced motility, toxin secretion, and cellular toxicity. Aeromonas hydrophila is a common aquatic bacterium that has increasingly been implicated in serious human infections. While many determinants of virulence have been identified in Aeromonas, rapid identification of pathogenic versus nonpathogenic

  18. Comparative transcriptomic analyses of vegetable and grain pea (Pisum sativum L. seed development

    Directory of Open Access Journals (Sweden)

    Na eLiu

    2015-11-01

    Full Text Available Understanding the molecular mechanisms regulating pea seed developmental process is extremely important for pea breeding. In this study, we used high-throughput RNA-Seq and bioinformatics analyses to examine the changes in gene expression during seed development in vegetable pea and grain pea, and compare the gene expression profiles of these two pea types. RNA-Seq generated 18.7 G of raw data, which were then de novo assembled into 77,273 unigenes with a mean length of 930 bp. Our results illustrate that transcriptional control during pea seed development is a highly coordinated process. There were 459 and 801 genes differentially expressed at early and late seed maturation stages between vegetable pea and grain pea, respectively. Soluble sugar and starch metabolism related genes were significantly activated during the development of pea seeds coinciding with the onset of accumulation of sugar and starch in the seeds. A comparative analysis of genes involved in sugar and starch biosynthesis in vegetable pea (high seed soluble sugar and low starch and grain pea (high seed starch and low soluble sugar revealed that differential expression of related genes at late development stages results in a negative correlation between soluble sugar and starch biosynthetic flux in vegetable and grain pea seeds. RNA-Seq data was validated by using real-time quantitative RT-PCR analysis for 30 randomly selected genes. To our knowledge, this work represents the first report of seed development transcriptomics in pea. The obtained results provide a foundation to support future efforts to unravel the underlying mechanisms that control the developmental biology of pea seeds, and serve as a valuable resource for improving pea breeding.

  19. Evolutionary trajectories of snake genes and genomes revealed by comparative analyses of five-pacer viper

    Science.gov (United States)

    Yin, Wei; Wang, Zong-ji; Li, Qi-ye; Lian, Jin-ming; Zhou, Yang; Lu, Bing-zheng; Jin, Li-jun; Qiu, Peng-xin; Zhang, Pei; Zhu, Wen-bo; Wen, Bo; Huang, Yi-jun; Lin, Zhi-long; Qiu, Bi-tao; Su, Xing-wen; Yang, Huan-ming; Zhang, Guo-jie; Yan, Guang-mei; Zhou, Qi

    2016-01-01

    Snakes have numerous features distinctive from other tetrapods and a rich history of genome evolution that is still obscure. Here, we report the high-quality genome of the five-pacer viper, Deinagkistrodon acutus, and comparative analyses with other representative snake and lizard genomes. We map the evolutionary trajectories of transposable elements (TEs), developmental genes and sex chromosomes onto the snake phylogeny. TEs exhibit dynamic lineage-specific expansion, and many viper TEs show brain-specific gene expression along with their nearby genes. We detect signatures of adaptive evolution in olfactory, venom and thermal-sensing genes and also functional degeneration of genes associated with vision and hearing. Lineage-specific relaxation of functional constraints on respective Hox and Tbx limb-patterning genes supports fossil evidence for a successive loss of forelimbs then hindlimbs during snake evolution. Finally, we infer that the ZW sex chromosome pair had undergone at least three recombination suppression events in the ancestor of advanced snakes. These results altogether forge a framework for our deep understanding into snakes' history of molecular evolution. PMID:27708285

  20. Taking a comparative approach: analysing personality as a multivariate behavioural response across species.

    Directory of Open Access Journals (Sweden)

    Alecia J Carter

    Full Text Available Animal personality, repeatable behaviour through time and across contexts, is ecologically and evolutionarily important as it can account for the exhibition of sub-optimal behaviours. Interspecific comparisons have been suggested as important for understanding the evolution of animal personality; however, these are seldom accomplished due, in part, to the lack of statistical tools for quantifying differences and similarities in behaviour between groups of individuals. We used nine species of closely-related coral reef fishes to investigate the usefulness of ecological community analyses for the analysis of between-species behavioural differences and behavioural heterogeneity. We first documented behavioural carryover across species by observing the fishes' behaviour and measuring their response to a threatening stimulus to quantify boldness. Bold fish spent more time away from the reef and fed more than shy fish. We then used ecological community analysis tools (canonical variate analysis, multi-response permutation procedure, and permutational analysis of multivariate dispersion and identified four 'clusters' of behaviourally similar fishes, and found that the species differ in the behavioural variation expressed; some species are more behaviourally heterogeneous than others. We found that ecological community analysis tools are easily and fruitfully applied to comparative studies of personality and encourage their use by future studies.

  1. Comparative proteomic analyses of macular and peripheral retina of cynomolgus monkeys (Macaca fascicularis).

    Science.gov (United States)

    Okamoto, Haru; Umeda, Shinsuke; Nozawa, Takehiro; Suzuki, Michihiro T; Yoshikawa, Yasuhiro; Matsuura, Etsuko T; Iwata, Takeshi

    2010-01-01

    The central region of the primate retina is called the macula. The fovea is located at the center of the macula, where the photoreceptors are concentrated to create a neural network adapted for high visual acuity. Damage to the fovea, e.g., by macular dystrophies and age-related macular degeneration, can reduce central visual acuity. The molecular mechanisms leading to these diseases are most likely dependent on the proteins in the macula which differ from those in the peripheral retina in expression level. To investigate whether the distribution of proteins in the macula is different from the peripheral retina, proteomic analyses of tissues from these two regions of cynomolgus monkeys were compared. Two-dimensional gel electrophoresis and mass spectrometry identified 26 proteins that were present only in the macular gel spots. The expression levels of five proteins, cone photoreceptor specific arrestin-C, gamma-synuclein, epidermal fatty acid binding protein, tropomyosin 1alpha chain, and heterogeneous nuclear ribonucleoproteins A2/B1, were significantly higher in the macula than in the peripheral retina. Immunostaining of macula sections by antibodies to each identified protein revealed unique localization in the retina, retinal pigment epithelial cells and the choroidal layer. Some of these proteins were located in cells with higher densities in the macula. We suggest that it will be important to study these proteins to determine their contribution to the pathogenesis and progression of macula diseases.

  2. Systematic comparative and sensitivity analyses of additive and outranking techniques for supporting impact significance assessments

    International Nuclear Information System (INIS)

    Cloquell-Ballester, Vicente-Agustin; Monterde-Diaz, Rafael; Cloquell-Ballester, Victor-Andres; Santamarina-Siurana, Maria-Cristina

    2007-01-01

    Assessing the significance of environmental impacts is one of the most important and all together difficult processes of Environmental Impact Assessment. This is largely due to the multicriteria nature of the problem. To date, decision techniques used in the process suffer from two drawbacks, namely the problem of compensation and the problem of identification of the 'exact boundary' between sub-ranges. This article discusses these issues and proposes a methodology for determining the significance of environmental impacts based on comparative and sensitivity analyses using the Electre TRI technique. An application of the methodology for the environmental assessment of a Power Plant project within the Valencian Region (Spain) is presented, and its performance evaluated. It is concluded that contrary to other techniques, Electre TRI automatically identifies those cases where allocation of significance categories is most difficult and, when combined with sensitivity analysis, offers greatest robustness in the face of variation in weights of the significance attributes. Likewise, this research demonstrates the efficacy of systematic comparison between Electre TRI and sum-based techniques, in the solution of assignment problems. The proposed methodology can therefore be regarded as a successful aid to the decision-maker, who will ultimately take the final decision

  3. Comparative analyses of the complete mitochondrial genomes of Dosinia clams and their phylogenetic position within Veneridae.

    Science.gov (United States)

    Lv, Changda; Li, Qi; Kong, Lingfeng

    2018-01-01

    Mitochondrial genomes have proved to be a powerful tool in resolving phylogenetic relationship. In order to understand the mitogenome characteristics and phylogenetic position of the genus Dosinia, we sequenced the complete mitochondrial genomes of Dosinia altior and Dosinia troscheli (Bivalvia: Veneridae), compared them with that of Dosinia japonica and established a phylogenetic tree for Veneridae. The mitogenomes of D. altior (17,536 bp) and D. troscheli (17,229 bp) are the two smallest in Veneridae, which include 13 protein-coding genes, 2 ribosomal RNA genes, 22 tRNA genes, and non-coding regions. The mitogenomes of the Dosinia species are similar in size, gene content, AT content, AT- and GC- skews, and gene arrangement. The phylogenetic relationships of family Veneridae were established based on 12 concatenated protein-coding genes using maximum likelihood and Bayesian analyses, which supported that Dosininae and Meretricinae have a closer relationship, with Tapetinae being the sister taxon. The information obtained in this study will contribute to further understanding of the molecular features of bivalve mitogenomes and the evolutionary history of the genus Dosinia.

  4. Vergleichende Analyse der Expression des Glukokortikoid-Rezeptors und der NF-kappaB Untereinheit p50 in Lymphozyten von Patienten mit rheumatoider Arthritis und Gesunden

    OpenAIRE

    Klüter, Andreas

    2003-01-01

    Zielstellung: Es wurden die Expression des antiinflammatorisch wirkenden Transkriptionsfaktors Glukokortikoid-Rezeptor (GR) und der Untereinheit p50 des proinflammatorischen Transkriptionsfaktor NF-kappaB in peripheren mononuklearen Blutzellen (PBMC) von Patienten mit rheumatoider Arthritis (RA) untersucht. Methode: Es wurden unbehandelte und mit Glukokortikoiden vorbehandelte RA-Patienten sowie gesunde Probanden verglichen. Die Expressionsanalyse von GR und der NF-kappaB Untereinheit p50 ...

  5. Le mythe du jeune désœuvré: analyse des interventions DDR en Côte d’Ivoire

    NARCIS (Netherlands)

    Chelpi-den Hamer, M.

    2009-01-01

    Les processus de prévention et de résolution des conflits sont en grande partie basés sur l’idée qu’un changement positif peut être induit par des interventions ciblées et planifiées. Il faut pourtant éviter de surestimer l’impact de telles interventions. Cet article explore comment de jeunes civils

  6. Méthodes d'analyse/synthèse et représentations optimales des sons musicaux basées sur la réduction de données spectrales

    OpenAIRE

    Rochebois , Thierry

    1997-01-01

    This thesis introduces a method that allows systematic reduction of data representing musical sounds. This method and its variants allows fast and dynamic synthesis of musical sounds.; Les applications de l'analyse et de la synthèse des sons musicaux sont primordiales a l'heure du multimédia. Nous présentons une méthode permettant d'analyser et de synthétiser les sons musicaux. Cette méthode, illustrée au chapitre 2, se décompose en trois étapes. La première repose sur une analyse spectrale p...

  7. L`ANALYSE COMPARATIVE DES FUSIONS-ACQUISITIONS AVEC LES AUTRES FORMES DE CROISSANCE DES ENTREPRISES (I- FUSIONS-ACQUISITIONS VS. CROISSANCE INTERNE

    Directory of Open Access Journals (Sweden)

    Vancea Mariana

    2010-07-01

    Full Text Available In order to achieve growth and development strategy, companies can choose between continuous improvement or optimization of operational and financial assets, on one hand, and on the other hand the achievement of mergers and acquisitions, as also strategic partnerships with other companies. The purpose of this paper is to analyze the company’s growth and development strategy through mergers and acquisitions by comparison with that of organic growth, while highlighting the advantages and disadvantages of each type of strategy.

  8. Comparative genomic analyses of Mycoplasma hyopneumoniae pathogenic 168 strain and its high-passaged attenuated strain

    Science.gov (United States)

    2013-01-01

    Background Mycoplasma hyopneumoniae is the causative agent of porcine enzootic pneumonia (EP), a mild, chronic pneumonia of swine. Despite presenting with low direct mortality, EP is responsible for major economic losses in the pig industry. To identify the virulence-associated determinants of M. hyopneumoniae, we determined the whole genome sequence of M. hyopneumoniae strain 168 and its attenuated high-passage strain 168-L and carried out comparative genomic analyses. Results We performed the first comprehensive analysis of M. hyopneumoniae strain 168 and its attenuated strain and made a preliminary survey of coding sequences (CDSs) that may be related to virulence. The 168-L genome has a highly similar gene content and order to that of 168, but is 4,483 bp smaller because there are 60 insertions and 43 deletions in 168-L. Besides these indels, 227 single nucleotide variations (SNVs) were identified. We further investigated the variants that affected CDSs, and compared them to reported virulence determinants. Notably, almost all of the reported virulence determinants are included in these variants affected CDSs. In addition to variations previously described in mycoplasma adhesins (P97, P102, P146, P159, P216, and LppT), cell envelope proteins (P95), cell surface antigens (P36), secreted proteins and chaperone protein (DnaK), mutations in genes related to metabolism and growth may also contribute to the attenuated virulence in 168-L. Furthermore, many mutations were located in the previously described repeat motif, which may be of primary importance for virulence. Conclusions We studied the virulence attenuation mechanism of M. hyopneumoniae by comparative genomic analysis of virulent strain 168 and its attenuated high-passage strain 168-L. Our findings provide a preliminary survey of CDSs that may be related to virulence. While these include reported virulence-related genes, other novel virulence determinants were also detected. This new information will form

  9. Etude comparative de la mortalite hospitaliere des enfants de 0-5 ...

    African Journals Online (AJOL)

    Objectifs: Comparer les caractéristiques de la mortalité infantojuvénile au CHR - Tsévié en 2003 et en 2008. Méthodologie: Il s'agit d'une étude ... L'équipement en matériels de réanimation, de même que le recrutement de personnel qualifié s'imposent pour réduire cette mortalité. Mots clés: Mortalité, enfants, Togo.

  10. Impact potentiel du mécanisme de développement propre dans l’avenir des cultures pérennes : état des négociations internationales et analyse prospective à travers l’exemple de la filière de production du caoutchouc naturel

    Directory of Open Access Journals (Sweden)

    Hamel Olivier

    2001-11-01

    éfavorable introduit de graves incertitudes sur le renouvellement de ces spéculations, qui pourraient entraîner des désordres écologiques et sociaux importants si des mécanismes de soutien n’étaient pas mis en œuvre. À un moment où la notion de « développement durable et propre » s’impose et où la protection des ressources naturelles (et des fonctions de production de services associés devient un objectif prioritaire au même titre que la lutte contre la pauvreté, cette situation est paradoxale. L’objet de cette présentation est donc à la fois : - d’alerter les pays du Sud sur une absence de prise en considération des problématiques des cultures pérennes dans le cadre des discussions portant sur les « puits » de carbone et sur la mise en œuvre du mécanisme de développement propre (MDP ; - d’analyser dans quelle mesure la valorisation du carbone (non émis ou séquestré, induite par le protocole de Kyoto et les mécanismes de flexibilité, est de nature à modifier les logiques économiques et les stratégies de développement des cultures pérennes.

  11. Comparative analyses of forest fuels in a life cycle perspective with a focus on transport systems

    Energy Technology Data Exchange (ETDEWEB)

    Eriksson, Lisa Naeslund [Ecotechnology, Department of Engineering, Physics and Mathematics, Mid Sweden University, SE-831 25 Oestersund (Sweden)

    2008-08-15

    Local, national and international transportation of forest fuels with regard to costs, primary energy use and CO{sub 2} emission was analysed. The main issue was the extent to which both mode and distance of transport affect the monetary cost, CO{sub 2} emission and primary energy use arising from the use of various types of forest residues for energy purpose. Local applications proved the most efficient options of those studied. Chipping of bundles at a terminal, for transport by rail and sea to national or international end-users, has low costs and produces only modest CO{sub 2} emissions. For the pellet options, the cost is about the same as for chipping, but require more primary energy and emit more CO{sub 2}. The traditional chipping system is more expensive than the other options. The costs of the international options over a transport distance of 1100 km vary between 21 and 28 EUR{sub 2007}/MWh, whereas pellet options cost between 22 and 25 EUR{sub 2007}/MWh. The primary energy required for transport of logging residues vis-a-vis pellets falls in the range 4-7% and 2-4%, respectively, of the bio-energy delivered. The primary energy needed to produce pellets gives them a lower fossil fuel substitution rate per hectare, compared with bundle systems. Similarly, for chip systems vis-a-vis bundle systems, the biomass delivered to the conversion plant is reduced by the greater physical dry-matter losses entailed by chipping systems in the forest-fuel chain. (author)

  12. Selective insectivory at Toro-Semliki, Uganda: comparative analyses suggest no 'savanna' chimpanzee pattern.

    Science.gov (United States)

    Webster, Timothy H; McGrew, William C; Marchant, Linda F; Payne, Charlotte L R; Hunt, Kevin D

    2014-06-01

    Chimpanzee (Pan troglodytes) insectivory across Africa is ubiquitous. Insects provide a significant nutritional payoff and may be important for chimpanzees in dry, open habitats with narrow diets. We tested this hypothesis at Semliki, Uganda, a long-term dry study site. We evaluated prospects for insectivory by measuring insect abundance along de novo transects and trails, monitoring social insect colonies, and surveying available raw materials for elementary technology. We determined the frequency and nature of insectivory through behavioral observation and fecal analysis. We then compared our results with those from 15 other long-term chimpanzee study sites using a cluster analysis. We found that Semliki chimpanzees are one of the most insectivorous populations studied to date in terms of frequency of consumption, but they are very selective in their insectivory, regularly consuming only weaver ants (Oecophylla longinoda) and honey and bees from hives of Apis mellifera. This selectivity obtains despite having a full range of typical prey species available in harvestable quantities. We suggest that Semliki chimpanzees may face ecological time constraints and therefore bias their predation toward prey taxa that can be quickly consumed. Geographical proximity correlated with the results of the cluster analysis, while rainfall, a relatively gross measure of environment, did not. Because broad taxonomic groups of insects were used in analyses, prey availability was unlikely to have a strong effect on this pattern. Instead, we suggest that transmission of cultural knowledge may play a role in determining chimpanzee prey selection across Africa. Further study is needed to test these hypotheses. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. Comparative modeling analyses of Cs-137 fate in the rivers impacted by Chernobyl and Fukushima accidents

    Energy Technology Data Exchange (ETDEWEB)

    Zheleznyak, M.; Kivva, S. [Institute of Environmental Radioactivity, Fukushima University (Japan)

    2014-07-01

    The consequences of two largest nuclear accidents of the last decades - at Chernobyl Nuclear Power Plant (ChNPP) (1986) and at Fukushima Daiichi NPP (FDNPP) (2011) clearly demonstrated that radioactive contamination of water bodies in vicinity of NPP and on the waterways from it, e.g., river- reservoir water after Chernobyl accident and rivers and coastal marine waters after Fukushima accident, in the both cases have been one of the main sources of the public concerns on the accident consequences. The higher weight of water contamination in public perception of the accidents consequences in comparison with the real fraction of doses via aquatic pathways in comparison with other dose components is a specificity of public perception of environmental contamination. This psychological phenomenon that was confirmed after these accidents provides supplementary arguments that the reliable simulation and prediction of the radionuclide dynamics in water and sediments is important part of the post-accidental radioecological research. The purpose of the research is to use the experience of the modeling activities f conducted for the past more than 25 years within the Chernobyl affected Pripyat River and Dnieper River watershed as also data of the new monitoring studies in Japan of Abukuma River (largest in the region - the watershed area is 5400 km{sup 2}), Kuchibuto River, Uta River, Niita River, Natsui River, Same River, as also of the studies on the specific of the 'water-sediment' {sup 137}Cs exchanges in this area to refine the 1-D model RIVTOX and 2-D model COASTOX for the increasing of the predictive power of the modeling technologies. The results of the modeling studies are applied for more accurate prediction of water/sediment radionuclide contamination of rivers and reservoirs in the Fukushima Prefecture and for the comparative analyses of the efficiency of the of the post -accidental measures to diminish the contamination of the water bodies. Document

  14. Functional and comparative genomics analyses of pmp22 in medaka fish

    Directory of Open Access Journals (Sweden)

    Kawarabayasi Yutaka

    2009-06-01

    Full Text Available Abstract Background Pmp22, a member of the junction protein family Claudin/EMP/PMP22, plays an important role in myelin formation. Increase of pmp22 transcription causes peripheral neuropathy, Charcot-Marie-Tooth disease type1A (CMT1A. The pathophysiological phenotype of CMT1A is aberrant axonal myelination which induces a reduction in nerve conduction velocity (NCV. Several CMT1A model rodents have been established by overexpressing pmp22. Thus, it is thought that pmp22 expression must be tightly regulated for correct myelin formation in mammals. Interestingly, the myelin sheath is also present in other jawed vertebrates. The purpose of this study is to analyze the evolutionary conservation of the association between pmp22 transcription level and vertebrate myelin formation, and to find the conserved non-coding sequences for pmp22 regulation by comparative genomics analyses between jawed fishes and mammals. Results A transgenic pmp22 over-expression medaka fish line was established. The transgenic fish had approximately one fifth the peripheral NCV values of controls, and aberrant myelination of transgenic fish in the peripheral nerve system (PNS was observed. We successfully confirmed that medaka fish pmp22 has the same exon-intron structure as mammals, and identified some known conserved regulatory motifs. Furthermore, we found novel conserved sequences in the first intron and 3'UTR. Conclusion Medaka fish undergo abnormalities in the PNS when pmp22 transcription increases. This result indicates that an adequate pmp22 transcription level is necessary for correct myelination of jawed vertebrates. Comparison of pmp22 orthologs between distantly related species identifies evolutionary conserved sequences that contribute to precise regulation of pmp22 expression.

  15. Comparative analyses of plastid genomes from fourteen Cornales species: inferences for phylogenetic relationships and genome evolution.

    Science.gov (United States)

    Fu, Chao-Nan; Li, Hong-Tao; Milne, Richard; Zhang, Ting; Ma, Peng-Fei; Yang, Jing; Li, De-Zhu; Gao, Lian-Ming

    2017-12-08

    The Cornales is the basal lineage of the asterids, the largest angiosperm clade. Phylogenetic relationships within the order were previously not fully resolved. Fifteen plastid genomes representing 14 species, ten genera and seven families of Cornales were newly sequenced for comparative analyses of genome features, evolution, and phylogenomics based on different partitioning schemes and filtering strategies. All plastomes of the 14 Cornales species had the typical quadripartite structure with a genome size ranging from 156,567 bp to 158,715 bp, which included two inverted repeats (25,859-26,451 bp) separated by a large single-copy region (86,089-87,835 bp) and a small single-copy region (18,250-18,856 bp) region. These plastomes encoded the same set of 114 unique genes including 31 transfer RNA, 4 ribosomal RNA and 79 coding genes, with an identical gene order across all examined Cornales species. Two genes (rpl22 and ycf15) contained premature stop codons in seven and five species respectively. The phylogenetic relationships among all sampled species were fully resolved with maximum support. Different filtering strategies (none, light and strict) of sequence alignment did not have an effect on these relationships. The topology recovered from coding and noncoding data sets was the same as for the whole plastome, regardless of filtering strategy. Moreover, mutational hotspots and highly informative regions were identified. Phylogenetic relationships among families and intergeneric relationships within family of Cornales were well resolved. Different filtering strategies and partitioning schemes do not influence the relationships. Plastid genomes have great potential to resolve deep phylogenetic relationships of plants.

  16. Comparative Proteomic and Morphological Change Analyses of Staphylococcus aureus During Resuscitation From Prolonged Freezing

    Science.gov (United States)

    Suo, Biao; Yang, Hua; Wang, Yuexia; Lv, Haipeng; Li, Zhen; Xu, Chao; Ai, Zhilu

    2018-01-01

    When frozen, Staphylococcus aureus survives in a sublethally injured state. However, S. aureus can recover at a suitable temperature, which poses a threat to food safety. To elucidate the resuscitation mechanism of freezing survived S. aureus, we used cells stored at -18°C for 90 days as controls. After resuscitating the survived cells at 37°C, the viable cell numbers were determined on tryptic soy agar with 0.6% yeast extract (TSAYE), and the non-injured-cell numbers were determined on TSAYE supplemented with 10% NaCl. The results showed that the total viable cell number did not increase within the first 3 h of resuscitation, but the osmotic regulation ability of freezing survived cells gradually recovered to the level of healthy cells, which was evidenced by the lack of difference between the two samples seen by differential cell enumeration. Scanning electron microscopy (SEM) showed that, compared to late exponential stage cells, some frozen survived cells underwent splitting and cell lysis due to deep distortion and membrane rupture. Transmission electron microscopy (TEM) showed that, in most of the frozen survived cells, the nucleoids (low electronic density area) were loose, and the cytoplasmic matrices (high electronic density area) were sparse. Additionally, a gap was seen to form between the cytoplasmic membranes and the cell walls in the frozen survived cells. The morphological changes were restored when the survived cells were resuscitated at 37°C. We also analyzed the differential proteome after resuscitation using non-labeled high-performance liquid chromatography–mass spectrometry (HPLC-MS). The results showed that, compared with freezing survived S. aureus cells, the cells resuscitated for 1 h had 45 upregulated and 73 downregulated proteins. The differentially expressed proteins were functionally categorized by gene ontology enrichment, KEGG pathway, and STRING analyses. Cell membrane synthesis-related proteins, oxidative stress resistance

  17. Comparative analyses of two Geraniaceae transcriptomes using next-generation sequencing.

    Science.gov (United States)

    Zhang, Jin; Ruhlman, Tracey A; Mower, Jeffrey P; Jansen, Robert K

    2013-12-29

    Organelle genomes of Geraniaceae exhibit several unusual evolutionary phenomena compared to other angiosperm families including accelerated nucleotide substitution rates, widespread gene loss, reduced RNA editing, and extensive genomic rearrangements. Since most organelle-encoded proteins function in multi-subunit complexes that also contain nuclear-encoded proteins, it is likely that the atypical organellar phenomena affect the evolution of nuclear genes encoding organellar proteins. To begin to unravel the complex co-evolutionary interplay between organellar and nuclear genomes in this family, we sequenced nuclear transcriptomes of two species, Geranium maderense and Pelargonium x hortorum. Normalized cDNA libraries of G. maderense and P. x hortorum were used for transcriptome sequencing. Five assemblers (MIRA, Newbler, SOAPdenovo, SOAPdenovo-trans [SOAPtrans], Trinity) and two next-generation technologies (454 and Illumina) were compared to determine the optimal transcriptome sequencing approach. Trinity provided the highest quality assembly of Illumina data with the deepest transcriptome coverage. An analysis to determine the amount of sequencing needed for de novo assembly revealed diminishing returns of coverage and quality with data sets larger than sixty million Illumina paired end reads for both species. The G. maderense and P. x hortorum transcriptomes contained fewer transcripts encoding the PLS subclass of PPR proteins relative to other angiosperms, consistent with reduced mitochondrial RNA editing activity in Geraniaceae. In addition, transcripts for all six plastid targeted sigma factors were identified in both transcriptomes, suggesting that one of the highly divergent rpoA-like ORFs in the P. x hortorum plastid genome is functional. The findings support the use of the Illumina platform and assemblers optimized for transcriptome assembly, such as Trinity or SOAPtrans, to generate high-quality de novo transcriptomes with broad coverage. In addition

  18. Possibilities of gas-phase radio-chromatography application to permanent-gas analysis; Possibilites de la radiochromatographie en phase gazeuse applications a l'analyse des gaz permanents

    Energy Technology Data Exchange (ETDEWEB)

    Dupuis, M C; Charrier, G; Alba, C; Massimino, D [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes

    1970-07-01

    The gas-phase radio-chromatography technique has been applied to the rapid analysis of permanent gases (H{sub 2}, O{sub 2}, N{sub 2}, A, Kr, Xe, CO, CH{sub 4}) labelled with radioactive indicators ({sup 3}H, {sup 37}A, {sup 85}Kr, {sup 133}Xe). After calibration, the components of such a mixture can be identified and their concentrations measured in less than two hours, using a sample volume of from 0.1 to 10 cm{sup 3}. The minimum detectable activity is of the order of 10{sup -4} {mu}C for each radioactive isotope. The measurements are reproducible to about 2 to 3 per cent. This work has been mainly concerned with the influence of parameters affecting the response of the radioactivity detector (ionization chamber or gas flow proportional counter). The method has very numerous applications both theoretically, for the study of chromatographic phenomena under ideal conditions (infinitesimal concentrations made possible by the use of radioactive tracers), and practically, for rapid and accurate radiochemical analysis of radioactive gas mixtures. (authors) [French] La technique de radiochromatographie en phase gazeuse est appliquee a l'analyse rapide de gaz permanents (H{sub 2}, O{sub 2}, N{sub 2}, A, Kr, Xe, CO, CH{sub 4}) marques par des indicateurs radioactifs ({sup 3}H, {sup 37}A, {sup 85}Kr, {sup 133}Xe). Apres etalonnage, l'identification et la mesure des concentrations des constituants d'un tel melange requierent moins de deux heures, sur un volume d'echantillon de 0.1 a 10 cm{sup 3}. L'activite minimum detectable est de l'ordre de 10{sup -4} {mu}C pour chaque isotope radioactif. La reproductibilite des mesures est de l'ordre de 2 a 3 pour cent. L'etude porte principalement sur l'influence des parametres affectant la reponse du detecteur de radioactivite (chambre d'ionisation, ou compteur proportionnel a circulation). La methode est extremement fertile en applications tant sur le plan theorique pour l'etude du phenomene chromatographique dans les conditions

  19. Possibilities of gas-phase radio-chromatography application to permanent-gas analysis; Possibilites de la radiochromatographie en phase gazeuse applications a l'analyse des gaz permanents

    Energy Technology Data Exchange (ETDEWEB)

    Dupuis, M.C.; Charrier, G.; Alba, C.; Massimino, D. [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes

    1970-07-01

    The gas-phase radio-chromatography technique has been applied to the rapid analysis of permanent gases (H{sub 2}, O{sub 2}, N{sub 2}, A, Kr, Xe, CO, CH{sub 4}) labelled with radioactive indicators ({sup 3}H, {sup 37}A, {sup 85}Kr, {sup 133}Xe). After calibration, the components of such a mixture can be identified and their concentrations measured in less than two hours, using a sample volume of from 0.1 to 10 cm{sup 3}. The minimum detectable activity is of the order of 10{sup -4} {mu}C for each radioactive isotope. The measurements are reproducible to about 2 to 3 per cent. This work has been mainly concerned with the influence of parameters affecting the response of the radioactivity detector (ionization chamber or gas flow proportional counter). The method has very numerous applications both theoretically, for the study of chromatographic phenomena under ideal conditions (infinitesimal concentrations made possible by the use of radioactive tracers), and practically, for rapid and accurate radiochemical analysis of radioactive gas mixtures. (authors) [French] La technique de radiochromatographie en phase gazeuse est appliquee a l'analyse rapide de gaz permanents (H{sub 2}, O{sub 2}, N{sub 2}, A, Kr, Xe, CO, CH{sub 4}) marques par des indicateurs radioactifs ({sup 3}H, {sup 37}A, {sup 85}Kr, {sup 133}Xe). Apres etalonnage, l'identification et la mesure des concentrations des constituants d'un tel melange requierent moins de deux heures, sur un volume d'echantillon de 0.1 a 10 cm{sup 3}. L'activite minimum detectable est de l'ordre de 10{sup -4} {mu}C pour chaque isotope radioactif. La reproductibilite des mesures est de l'ordre de 2 a 3 pour cent. L'etude porte principalement sur l'influence des parametres affectant la reponse du detecteur de radioactivite (chambre d'ionisation, ou compteur proportionnel a circulation). La methode est extremement fertile en applications tant sur le plan theorique pour l

  20. Contribution to the micro-calorimetric study of the characteristics of radio-elements and to their qualitative and quantitative analysis; Contribution a l'etude microcalorimetrique des caracteristiques des radio-elements et a leurs analyses qualitative et quantitative

    Energy Technology Data Exchange (ETDEWEB)

    Ozias, Y [Centre de Production de Plutonium de Marcoule, 30 (France)

    1964-10-01

    equal to that obtained by mass spectrography (destruction of the sample) 1 to 3 per cent, and higher than that obtained by counting techniques (greater than 5 per cent). (author) [French] Le principe de cette etude consiste a enregistrer avec le microcalorimetre E. CALVET le flux d'energie emis par les radioelements en fonction du temps at a partir de cette courbe de determiner soit leurs caracteristiques (periode et energie du rayonnement), soit la composition d'un melange de radioelements. Dans une premiere partie on a adapte les relations theoriques de la radioactivite a l'etude microcalorimetrique. Dans une deuxieme partie on determine experimentalement au microcalorimetre E. CALVET les caracteristiques de divers radioelements, yttrium 90, phosphore 32, soufre 35, iode 131, etc. et leurs melanges. On a etudie plus particulierement l'analyse isotopique du melange de {sup 239}Pu, de {sup 240}Pu et eventuellement de {sup 241}Pu. La methode microcalorimetrique n'a pas la sensibilite des methodes classiques de comptage, sa limite actuelle para etre de l'ordre du micro-watt pour les appareils utilises, mais elle est la plus directe pour les emetteurs de rayonnements facilement absorbables({alpha} et {beta}). Pour les emetteurs {gamma} une partie seulement de l'energie est absorbee par les parois du recipient. La determination de leurs caracteristiques et de leurs masses dans les melanges ne depend ni de la forme, ni de la dilution, ni surtout de l'auto-absorption de la source. Pour des echantillons de forte activite, cette auto-absorption est pour les methodes classiques la source de grosses difficultes entra ant de multiples manipulations: divisions, mise en solution, dilutions qui introduisent autant de causes d'erreur. La methode calorimetrique permet de travailler sur l'echantillon brut. Toutes les mesures ont ete faites avec le microcalorimetre E. CALVET classique; mais pour effectuer une mesure tres precise de' l'energie due au rayonnement {gamma} il faut faire

  1. Une analyse des représentations des enseignants réfléchissant sur une expérience d’implantation d’un portfolio électronique / An Analysis of the Perceptions of Teachers Reflecting on an Experience of e-Portfolio Implementation

    Directory of Open Access Journals (Sweden)

    Ann-Louise Davidson

    2012-08-01

    Full Text Available Cet article rend compte d’une analyse des représentations avec des enseignants, qui a eu lieu à la fin d’une expérience d’implantation d’un portfolio électronique favorisant l’autorégulation des apprentissages des élèves et la professionnalisation des enseignants. Le texte s’appuie sur le contexte éducatif québécois actuel. Ensuite, il présente une revue de littérature entourant les compétences technologiques, les portfolios électroniques et l’autorégulation des apprentissages. La méthodologie présente le design de la recherche, les instruments utilisés pour les entretiens et pour animer le groupe de discussion. Les résultats montrent que pour une enseignante qui avait déjà adopté la pédagogie sous-jacente au renouveau pédagogique Québécois, le portfolio électronique était une expérience fort utile. Toutefois, pour les deux autres enseignants, l’implantation du portfolio électronique était beaucoup trop exigeante. Finalement, nous discutons des implications des résultats, autant au point de vue de l’expérience d’implantation des portfolios électroniques que du point de vue de la contribution méthodologique. This article presents an analysis of the perceptions of teachers, which took place in 2010 at the end of an experiment implementing an e-portfolio that facilitates student self-regulation of learning. The article is based on the current Quebec educational context. It presents a review of literature on technology skills, e-portfolios and the self-regulation of learning. The methodology describes the research design, the tools used in the individual interviews and in the group discussion. The results indicate that the e-portfolio was a valuable experience for a teacher who had already adopted the pedagogy underlying the education reform in Quebec. However the implementation of the e-portfolio was difficult for the other two teachers due to challenges in terms of technology and managing

  2. Complete chloroplast genome sequence of Elodea canadensis and comparative analyses with other monocot plastid genomes.

    Science.gov (United States)

    Huotari, Tea; Korpelainen, Helena

    2012-10-15

    Elodea canadensis is an aquatic angiosperm native to North America. It has attracted great attention due to its invasive nature when transported to new areas in its non-native range. We have determined the complete nucleotide sequence of the chloroplast (cp) genome of Elodea. Taxonomically Elodea is a basal monocot, and only few monocot cp genomes representing early lineages of monocots have been sequenced so far. The genome is a circular double-stranded DNA molecule 156,700 bp in length, and has a typical structure with large (LSC 86,194 bp) and small (SSC 17,810 bp) single-copy regions separated by a pair of inverted repeats (IRs 26,348 bp each). The Elodea cp genome contains 113 unique genes and 16 duplicated genes in the IR regions. A comparative analysis showed that the gene order and organization of the Elodea cp genome is almost identical to that of Amborella trichopoda, a basal angiosperm. The structure of IRs in Elodea is unique among monocot species with the whole cp genome sequenced. In Elodea and another monocot Lemna minor the borders between IRs and LSC are located upstream of rps 19 gene and downstream of trnH-GUG gene, while in most monocots, IR has extended to include both trnH and rps 19 genes. A phylogenetic analysis conducted using Bayesian method, based on the DNA sequences of 81 chloroplast genes from 17 monocot taxa provided support for the placement of Elodea together with Lemna as a basal monocot and the next diverging lineage of monocots after Acorales. In comparison with other monocots, the Elodea cp genome has gone through only few rearrangements or gene losses. IR of Elodea has a unique structure among the monocot species studied so far as its structure is similar to that of a basal angiosperm Amborella. This result together with phylogenetic analyses supports the placement of Elodea as a basal monocot to the next diverging lineage of monocots after Acorales. So far, only few cp genomes representing early lineages of monocots have been

  3. Comparative analyses of tooth wear in free-ranging and captive wild equids.

    Science.gov (United States)

    Taylor, L A; Müller, D W H; Schwitzer, C; Kaiser, T M; Castell, J C; Clauss, M; Schulz-Kornas, E

    2016-03-01

    Captive breeding has played a crucial role in the conservation of threatened equid species. Grazing ruminants and rhinoceros in captivity have less abrasion-dominated tooth wear than their free-ranging conspecifics, with potential negative consequences for their health. However, a similar study on wild equids in captivity is missing. The aim was to establish if different tooth wear patterns are exhibited by free-ranging and captive equids. Cross-sectional study of museum specimens comparing free-ranging and captive equids. Dental casts of maxillary cheek teeth of 228 museum specimens (122 from free-ranging and 106 from captive individuals) of 7 wild equid species were analysed using the extended mesowear method. Although teeth showing specific abnormalities were not scored, the presence of focal overgrowths (hooks) of the rostral premolars (106, 206) was recorded. Captive Equus ferus przewalskii, E. grevyi, E. hemionus, E. quagga boehmi and E. zebra hartmannae have less abrasion-dominated tooth wear on their premolars than their free-ranging conspecifics (P<0.001). Fewer differences were exhibited between populations in the molars. No differences were exhibited in the distal cusp of the molars (110, 210) between populations, except in a small sample of E. kiang. Captive equids exhibited more homogeneous wear along the tooth row whereas free-ranging equids exhibited a tooth wear gradient, with more abrasion on premolars than molars. There were more rostral hooks on the premolars (106, 206) in the captive than the free-ranging population (P = 0.02). Captive equids did experience less abrasion-dominated tooth wear than their free-ranging conspecifics, but the differences in tooth wear were less pronounced than those between captive and free-ranging wild ruminant and rhinoceros species. This indicates that feeding regimes for captive equids deviate less from natural diets than those for captive ruminants and rhinoceros but that factors leading to hook

  4. Usage pédagogique de Facebook dans une activité d’apprentissage en groupe par des étudiants tunisiens : analyse de l’efficacité du travail collaboratif

    Directory of Open Access Journals (Sweden)

    Hassen BEN REBAH

    2017-01-01

    Full Text Available Cet article présente une analyse de l’usage pédagogique du réseau socio-numérique Facebook comme dispositif d’apprentissage collaboratif à distance dans l’enseignement supérieur, notamment à l’Institut supérieur des études technologiques de Mahdia (Tunisie. Cette recherche qualitative vise à évaluer l’efficacité du travail collaboratif dans le cadre d’une activité d’apprentissage impliquant des étudiants en informatique. Nous tentons à cet effet de déterminer en quoi l’usage de Facebook comme outil de partage, de communication et d’échanges en réseau favoriserait la mise en place d’un processus efficace de co-construction des savoirs et d’interactions entre apprenants. Pour atteindre cet objectif, l’analyse s’appuie sur le paradigme de l’apprentissage social de Bandura (1977 qui met l’accent sur le jeu d’interactions permanentes entre les comportements d’un individu, son fonctionnement cognitif et les variables de l’environnement. Les données issues des traces d’activités sur le mur du groupe Facebook et des contenus d’entretiens semi-directifs ont permis après analyse d’établir que l’utilisation pédagogique de Facebook a effectivement favorisé la coproduction des savoirs attendus chez les étudiants au cours de l’activité. Ainsi, nous sommes parvenus à la conclusion que l’usage de Facebook est efficace pour la mise en place d’une activité d’apprentissage collaborative à distance. Cependant, cela nécessite l’élaboration en amont d’un véritable scénario de formation organisant le déroulement de l’activité.

  5. Contribution to the analysis of light elements using x fluorescence excited by radio-elements; Contribution a l'analyse des elements legers par fluorescence x excitee au moyen de radioelements

    Energy Technology Data Exchange (ETDEWEB)

    Robert, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-07-01

    In order to study the possibilities of using radioactive sources for the X-fluorescence analysis of light elements, the principle is given, after a brief description of X-fluorescence, of the excitation of this phenomenon by X, {beta} and {alpha} emission from radio-elements. The operation and use of the proportional gas counter for X-ray detection is described. A device has been studied for analysing the elements of the 2. and 3. periods of the Mendeleev table. It makes it possible to excite the fluorescence with a radioactive source emitting X-rays or a particles; the X-ray fluorescence penetrates into a window-less proportional counter, this being made possible by the use of an auxiliary electric field in the neighbourhood of the sample. The gas detection pressure leading to the maximum detection yield is given. The spectra are given for the K{sub {alpha}} lines of 3. period elements excited by {sup 55}Fe, {sup 3}H/Zr and {sup 210}Po sources; for the 2. period the K{sub {alpha}} spectra of carbon and of fluorine excited by the {alpha} particles of {sup 210}Po. (author) [French] Afin d'etudier les possibilites d'emploi de sources radioactives a l'analyse par fluorescence X des elements legers, on presente apres rappel de notions generales sur la fluorescence X, le principe de l'excitation de ce phenomene par emission X, {beta}, {alpha} de radioelements. Le fonctionnement et l'utilisation du compteur proportionnel a gaz a la detection du rayonnement X est developpe. Un dispositif permettant l'analyse des elements des 2eme et 3eme periodes de la classification de Mendeleev est etudie. Il permet l'excitation de la fluorescence par source radioactive emettrice de rayons X ou de particules {alpha}; le rayonnement X de fluorescence penetre dans un compteur proportionnel depourvu de fenetre, ceci est rendu possible en creant un champ electrique auxiliaire au voisinage de l'echantillon. On definit une pression du gaz de detection pour un rendement de detection maximal

  6. Contribution to the analysis of light elements using x fluorescence excited by radio-elements; Contribution a l'analyse des elements legers par fluorescence x excitee au moyen de radioelements

    Energy Technology Data Exchange (ETDEWEB)

    Robert, A. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-07-01

    In order to study the possibilities of using radioactive sources for the X-fluorescence analysis of light elements, the principle is given, after a brief description of X-fluorescence, of the excitation of this phenomenon by X, {beta} and {alpha} emission from radio-elements. The operation and use of the proportional gas counter for X-ray detection is described. A device has been studied for analysing the elements of the 2. and 3. periods of the Mendeleev table. It makes it possible to excite the fluorescence with a radioactive source emitting X-rays or a particles; the X-ray fluorescence penetrates into a window-less proportional counter, this being made possible by the use of an auxiliary electric field in the neighbourhood of the sample. The gas detection pressure leading to the maximum detection yield is given. The spectra are given for the K{sub {alpha}} lines of 3. period elements excited by {sup 55}Fe, {sup 3}H/Zr and {sup 210}Po sources; for the 2. period the K{sub {alpha}} spectra of carbon and of fluorine excited by the {alpha} particles of {sup 210}Po. (author) [French] Afin d'etudier les possibilites d'emploi de sources radioactives a l'analyse par fluorescence X des elements legers, on presente apres rappel de notions generales sur la fluorescence X, le principe de l'excitation de ce phenomene par emission X, {beta}, {alpha} de radioelements. Le fonctionnement et l'utilisation du compteur proportionnel a gaz a la detection du rayonnement X est developpe. Un dispositif permettant l'analyse des elements des 2eme et 3eme periodes de la classification de Mendeleev est etudie. Il permet l'excitation de la fluorescence par source radioactive emettrice de rayons X ou de particules {alpha}; le rayonnement X de fluorescence penetre dans un compteur proportionnel depourvu de fenetre, ceci est rendu possible en creant un champ electrique auxiliaire au voisinage de l'echantillon. On definit une pression du gaz de detection

  7. Essai d’une méthodologie d’analyse des données d’Internet sur un ordinateur

    Directory of Open Access Journals (Sweden)

    Géraldine Foin

    2017-01-01

    Full Text Available Dans l’étude de l’environnement numérique dans lequel les individus vivent et évoluent, des problèmes méthodologiques peuvent se poser pour les chercheurs en sciences humaines et sociales. Cet article s’interroge sur la compatibilité des outils classiques en sciences sociales pour l’étude des pratiques numériques sur un écran, celui de l’ordinateur. En effet, l’usage classique d’entretiens, de questionnaires ou d’observations ne suffit plus pour recueillir avec précision les données relatives à Internet et ses écrans (pratique et consommation. Nous proposons une méthodologie complémentaire aux outils non numériques.

  8. L’investiture impériale comme fête. Une approche comparative des fêtes de couronnement

    OpenAIRE

    Rudolph, Harriet

    2013-01-01

    La fête peut être décrite comme un mode spécifique d’inclusion sociale qui se distingue par une occasion spécifique, sa mise en relief démonstrative par rapport au quotidien tout comme le caractère collectif et la dimension de représentation ostentatoire qui lui sont propres. Dans la fête se constituent des cadres d’actions tels que la cour princière, la ville, la commune ou la paroisse en tant que structures sociales et politiques. Les fêtes sont des événements de communication dont des acte...

  9. Contribution to the studies on the mineral content of plant material through radioactivation analysis; Contribution a l'etude de la composition minerale des matieres vegetales au moyen de l'analyse par radioactivation

    Energy Technology Data Exchange (ETDEWEB)

    Fourcy, A. [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1968-03-15

    Radioactivation analysis is by its great sensibility or its rapidity quite helpful in plant biology and agronomy. Specific composition of plants and results to obtain in biological experimentation have needed a practical research on analytical methods for plant materials, using for radioactivation swimming-pool reactor neutrons and 14 MeV neutrons from a generator. Dosage process for 25 elements is exposed, taking account of the interest of the analysis for each element, the average amount occurring in plants and the result obtained. Many applications are developed, concerning nutrition physiology, genetics, parasitology, toxicology, control of manufactured agricultural and pharmaceutical products industrial and pesticides residues, ecology, radioecology and biochemistry. (author) [French] L'analyse par radioactivation, par sa grande sensibilite ou sa rapidite, est susceptible de rendre de nombreux services en biologie vegetale et en agronomie. La composition particuliere des plantes et les buts recherches dans l'experimentation ont exige une etude concrete des methodes d'analyse propres a la matiere vegetale en utilisant, pour la radioactivation, soit un reacteur de type piscine a eau legere, soit un accelerateur generateur de neutrons de 14 MeV. Le mode de dosage de 25 elements est expose en tenant compte de l'interet de l'analyse de chaque element, des teneurs moyennes rencontrees dans les plantes, et du resultat atteint. De nombreuses applications sont developpees qui touchent a la physiologie de la nutrition, la genetique, la parasitologie, la toxicologie, le controle des fabrications, les pollutions industrielles, l'ecologie, la radioecologie et la biochimie. (auteur)

  10. Contribution to the studies on the mineral content of plant material through radioactivation analysis; Contribution a l'etude de la composition minerale des matieres vegetales au moyen de l'analyse par radioactivation

    Energy Technology Data Exchange (ETDEWEB)

    Fourcy, A [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1968-03-15

    Radioactivation analysis is by its great sensibility or its rapidity quite helpful in plant biology and agronomy. Specific composition of plants and results to obtain in biological experimentation have needed a practical research on analytical methods for plant materials, using for radioactivation swimming-pool reactor neutrons and 14 MeV neutrons from a generator. Dosage process for 25 elements is exposed, taking account of the interest of the analysis for each element, the average amount occurring in plants and the result obtained. Many applications are developed, concerning nutrition physiology, genetics, parasitology, toxicology, control of manufactured agricultural and pharmaceutical products industrial and pesticides residues, ecology, radioecology and biochemistry. (author) [French] L'analyse par radioactivation, par sa grande sensibilite ou sa rapidite, est susceptible de rendre de nombreux services en biologie vegetale et en agronomie. La composition particuliere des plantes et les buts recherches dans l'experimentation ont exige une etude concrete des methodes d'analyse propres a la matiere vegetale en utilisant, pour la radioactivation, soit un reacteur de type piscine a eau legere, soit un accelerateur generateur de neutrons de 14 MeV. Le mode de dosage de 25 elements est expose en tenant compte de l'interet de l'analyse de chaque element, des teneurs moyennes rencontrees dans les plantes, et du resultat atteint. De nombreuses applications sont developpees qui touchent a la physiologie de la nutrition, la genetique, la parasitologie, la toxicologie, le controle des fabrications, les pollutions industrielles, l'ecologie, la radioecologie et la biochimie. (auteur)

  11. Mass spectrometer introduction line: application to the analysis of impurities in uranium hexafluoride; Ligne d'introduction pour spectrometre de masse: application a l'analyse des impuretes contenues dans l'UF{sub 6}

    Energy Technology Data Exchange (ETDEWEB)

    Besson, M. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires. Departement de physico-chimie, service des isotopes stables, section de spectrometrie de masse

    1967-01-01

    The continuous mass-spectrometric analysis of impurities in UF{sub 6} is possible industrially if certain conditions imposed by the nature of the gas are respected. The gas introduction line arriving at the spectrometer's source makes it possible to fix the flow-rate, to control the inlet pressure and to selectively destroy the gas containing the impurities. The operational conditions for the line are defined and a description is given of the theoretical and experimental study of the various elements of which it is composed, i.e. the leak valve, the flow-meter, the chemical trap and the servo-mechanism making it possible to regulate and control the gas flow. The dynamic characteristics of the line's various components and the performance of the equipment in the case of the analyses considered are given. (author) [French] L'analyse en continu par spectrometrie de masse des impuretes contenus dans l'UF{sub 6} est possible industriellement moyennant certaines conditions imposees par la nature du gaz. La ligne d'introduction des gaz dans la source du spectrometre permet de regler le debit, de controler la pression d'introduction et de detruire selectivement le gaz porteur d'impuretes. Les conditions de fonctionnement de la ligne etant definies, on decrit l'etude theorique et experimentale des differents elements qui la composent, c'est-a-dire: le robinet a fuite, le debitmetre, le piege chimique et l'ensemble d'asservissement permettant la regulation et le controle du debit. On donne les caracteristiques dynamiques des differents constituants de la ligne et les performances de l'ensemble pour les analyses considerees. (auteur)

  12. Mass spectrometer introduction line: application to the analysis of impurities in uranium hexafluoride; Ligne d'introduction pour spectrometre de masse: application a l'analyse des impuretes contenues dans l'UF{sub 6}

    Energy Technology Data Exchange (ETDEWEB)

    Besson, M [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires. Departement de physico-chimie, service des isotopes stables, section de spectrometrie de masse

    1967-01-01

    The continuous mass-spectrometric analysis of impurities in UF{sub 6} is possible industrially if certain conditions imposed by the nature of the gas are respected. The gas introduction line arriving at the spectrometer's source makes it possible to fix the flow-rate, to control the inlet pressure and to selectively destroy the gas containing the impurities. The operational conditions for the line are defined and a description is given of the theoretical and experimental study of the various elements of which it is composed, i.e. the leak valve, the flow-meter, the chemical trap and the servo-mechanism making it possible to regulate and control the gas flow. The dynamic characteristics of the line's various components and the performance of the equipment in the case of the analyses considered are given. (author) [French] L'analyse en continu par spectrometrie de masse des impuretes contenus dans l'UF{sub 6} est possible industriellement moyennant certaines conditions imposees par la nature du gaz. La ligne d'introduction des gaz dans la source du spectrometre permet de regler le debit, de controler la pression d'introduction et de detruire selectivement le gaz porteur d'impuretes. Les conditions de fonctionnement de la ligne etant definies, on decrit l'etude theorique et experimentale des differents elements qui la composent, c'est-a-dire: le robinet a fuite, le debitmetre, le piege chimique et l'ensemble d'asservissement permettant la regulation et le controle du debit. On donne les caracteristiques dynamiques des differents constituants de la ligne et les performances de l'ensemble pour les analyses considerees. (auteur)

  13. Antistaphylococcal activity of DX-619, a new des-F(6)-quinolone, compared to those of other agents.

    Science.gov (United States)

    Bogdanovich, Tatiana; Esel, Duygu; Kelly, Linda M; Bozdogan, Bülent; Credito, Kim; Lin, Gengrong; Smith, Kathy; Ednie, Lois M; Hoellman, Dianne B; Appelbaum, Peter C

    2005-08-01

    The in vitro activity of DX-619, a new des-F(6)-quinolone, was tested against staphylococci and compared to those of other antimicrobials. DX-619 had the lowest MIC ranges/MIC(50)s/MIC(90)s (microg/ml) against 131 Staphylococcus aureus strains (32), and ciprofloxacin (>32/>32). Raised quinolone MICs were associated with mutations in GyrA (S84L) and single or double mutations in GrlA (S80F or Y; E84K, G, or V) in all S. aureus strains tested. A recent vancomycin-resistant S. aureus (VRSA) strain (Hershey) was resistant to available quinolones and was inhibited by DX-619 at 0.25 microg/ml and sitafloxacin at 1.0 microg/ml. Vancomycin (except VRSA), linezolid, ranbezolid, tigecycline, and quinupristin-dalfopristin were active against all strains, and teicoplanin was active against S. aureus but less active against coagulase-negative staphylococci. DX-619 produced resistant mutants with MICs of 1 to >32 microg/ml after 32 microg/ml for ciprofloxacin, sitafloxacin, moxifloxacin, and gatifloxacin. DX-619 and sitafloxacin were also more active than other tested drugs against selected mutants and had the lowest mutation frequencies in single-step resistance selection. DX-619 and sitafloxacin were bactericidal against six quinolone-resistant (including the VRSA) and seven quinolone-susceptible strains tested, whereas gatifloxacin, moxifloxacin, levofloxacin, and ciprofloxacin were bactericidal against 11, 10, 7, and 5 strains at 4x MIC after 24 h, respectively. DX-619 was also bactericidal against one other VRSA strain, five vancomycin-intermediate S. aureus strains, and four vancomycin-intermediate coagulase-negative staphylococci. Linezolid, ranbezolid, and tigecycline were bacteriostatic and quinupristin-dalfopristin, teicoplanin, and vancomycin were bactericidal against two, eight, and nine strains, and daptomycin and oritavancin were rapidly bactericidal against all strains, including the VRSA. DX-619 has potent in vitro activity against staphylococci, including

  14. Arbeitszeitflexibilisierung in der westdeutschen Metall- und Elektroindustrie und die Verbandsstrategien - Eine vergleichende Analyse der arbeitszeitpolitischen Strategien des Arbeitgeberverbandes Gesamtmetall und der Industriegewerkschaft Metall

    OpenAIRE

    Altun, Ufuk

    2005-01-01

    Arbeitszeitpolitik und Arbeitszeitgestaltung haben seit dem Tarifkompromiss im Jahre 1984 in der Metall-, und Elektroindustrie in der politischen und wissenschaftlichen Diskussion einen immensen Bedeutungszuwachs erfahren. Die Forderungen nach einer flexibleren Arbeitszeitgestaltung haben zeitgleich sowohl aus der Globalisierungsdiskussion und der Debatte um die Wettbewerbsfähigkeit des "Wirtschaftsstandorts Deutschland" heraus wie auch aus beschäftigungspolitischen Gründen neuen Auftrieb bek...

  15. Méthodologie d’analyse des signaux et caractérisation hydrogéologique : application aux chroniques de données obtenues aux laboratoires souterrains du Mont Terri, Tournemire et Meuse/Haute-Marne

    OpenAIRE

    Fatmi, Hassane

    2009-01-01

    Ce rapport présente des méthodes de prétraitement, d'analyse statistique et d'interprétation de chroniques hydrogéologiques de massifs peu perméables (argilites) dans le cadre d'études sur le stockage profond de déchets radioactifs. Les séries temporelles analysées sont la pression interstitielle et la pression atmosphérique, en relation avec différents phénomènes (marées terrestres, effet barométrique, évolution de l'excavation des galeries). Les pré-traitements permetten...

  16. Comparative Analysis of Upper Ocean Heat Content Variability from Ensemble Operational Ocean Analyses

    Science.gov (United States)

    Xue, Yan; Balmaseda, Magdalena A.; Boyer, Tim; Ferry, Nicolas; Good, Simon; Ishikawa, Ichiro; Rienecker, Michele; Rosati, Tony; Yin, Yonghong; Kumar, Arun

    2012-01-01

    Upper ocean heat content (HC) is one of the key indicators of climate variability on many time-scales extending from seasonal to interannual to long-term climate trends. For example, HC in the tropical Pacific provides information on thermocline anomalies that is critical for the longlead forecast skill of ENSO. Since HC variability is also associated with SST variability, a better understanding and monitoring of HC variability can help us understand and forecast SST variability associated with ENSO and other modes such as Indian Ocean Dipole (IOD), Pacific Decadal Oscillation (PDO), Tropical Atlantic Variability (TAV) and Atlantic Multidecadal Oscillation (AMO). An accurate ocean initialization of HC anomalies in coupled climate models could also contribute to skill in decadal climate prediction. Errors, and/or uncertainties, in the estimation of HC variability can be affected by many factors including uncertainties in surface forcings, ocean model biases, and deficiencies in data assimilation schemes. Changes in observing systems can also leave an imprint on the estimated variability. The availability of multiple operational ocean analyses (ORA) that are routinely produced by operational and research centers around the world provides an opportunity to assess uncertainties in HC analyses, to help identify gaps in observing systems as they impact the quality of ORAs and therefore climate model forecasts. A comparison of ORAs also gives an opportunity to identify deficiencies in data assimilation schemes, and can be used as a basis for development of real-time multi-model ensemble HC monitoring products. The OceanObs09 Conference called for an intercomparison of ORAs and use of ORAs for global ocean monitoring. As a follow up, we intercompared HC variations from ten ORAs -- two objective analyses based on in-situ data only and eight model analyses based on ocean data assimilation systems. The mean, annual cycle, interannual variability and longterm trend of HC have

  17. Interpersonal trust and mutually beneficial exchanges: Measuring social capital for comparative analyses

    Czech Academy of Sciences Publication Activity Database

    Matějů, Petr; Vitásková, Anna

    2006-01-01

    Roč. 42, č. 3 (2006), s. 493-516 ISSN 0038-0288 R&D Projects: GA MPS(CZ) 1J/005/04-DP2; GA ČR(CZ) GA403/03/0340 Institutional research plan: CEZ:AV0Z70280505 Keywords : social capital * trust * komparative analyse Subject RIV: AO - Sociology, Demography Impact factor: 0.128, year: 2006

  18. L’analyse des métaphores et les modèles de la métropole nord-américaine : débat et proposition

    Directory of Open Access Journals (Sweden)

    Gilles Sénécal

    2008-09-01

    Full Text Available Cet article passe en revue les différents modèles, depuis celui de l’école de Chicago jusqu’à celui de l’école de Los Angeles, qui représentent la forme des métropoles nord-américaines. L’analyse des métaphores, tant écologique ou gravitaire, que celles de la géographie des espaces-temps, des scènes urbaines ou du jeu keno, permet de revoir les termes du débat opposant le modèle gravitaire à celui de la métropole fragmentée. Deux questions sont ici soulevées. La première concerne l’unité des études urbaines contenue dans le modèle écologique, c’est-à-dire sa capacité de traiter de l’organisation de l’espace métropolitain et des interactions sociales réalisées à l’échelle du lieu. La seconde traite de la mobilité des personnes, c’est-à-dire de la relation entre l’organisation de l’espace métropolitain et l’espace vécu des individus. Deux constats se dégagent de l’analyse. Le premier est pour reconnaître le caractère inachevé de l’urbanisme postmoderne. La seconde souligne l’absence d’une métaphore de substitution pouvant  rendre compte de manière générale de la forme métropoles nord-américaines contemporaines. Face à quoi, il est proposé de s’inspirer de la théorie des cordes en sciences physiques.This paper reviews the various models representing the form of the North American metropolis, starting from the School of Chicago up to the School of Los Angeles. It examines a series of metaphors ranging from the ecological to the gravitational, as well as space-time geography, urban scene or the game Keno with the aim of reconsidering the terms of debate regarding the contrasts between the gravitational and the fragmented metropolis models. Two questions are raised. The first involves urban studies’ unity in the ecological model i.e. its capacity to consider the organization of metropolitan space and place-level social interactions. The second deals with the issue of

  19. La fabrique des sciences des institutions aux pratiques

    CERN Document Server

    Benninghoff, Martin; Crettaz von Roten, Fabienne; Merz, Martina

    2006-01-01

    Aujourd'hui, les façons de produire, d'organiser, d'évaluer et d'utiliser les savoirs sont en profond débat. De plus en plus, l'Etat, la société civile et l'économie tentent d'influencer les activités des universités et des laboratoires de recherche. Ces développements mettent à l'épreuve tout à la fois les fondements des systèmes d'enseignement supérieur et de recherche, l'autonomie des institutions scientifiques, la définition des frontières des savoirs et l'acceptation des sciences. Dans des contextes suisses et européens, cet ouvrage s'intéresse aux manières dont les sciences et les technologies sont fabriquées, en analysant leurs institutions et les pratiques. A partir d'une approche relationnelle, les sciences et les technologies sont conçues comme des phénomènes profondément sociaux, culturels et politiques. Une telle démarche déstabilise les visions parfois idéalisées et stéréotypées de la construction des savoirs. Des études de cas détaillées décrivent des phénomè...

  20. Spectral analyses of the Forel-Ule Ocean colour comparator scale

    NARCIS (Netherlands)

    Wernand, M.; van der Woerd, H.J.

    2010-01-01

    François Alphonse Forel (1890) and Willi Ule (1892) composed a colour comparator scale, with tints varying from indigo-blue to cola brown, to quantify the colour of natural waters, like seas, lakes and rivers. For each measurement, the observer compares the colour of the water above a submersed

  1. Reliability and vulnerability analyses of critical infrastructures: Comparing two approaches in the context of power systems

    International Nuclear Information System (INIS)

    Johansson, Jonas; Hassel, Henrik; Zio, Enrico

    2013-01-01

    Society depends on services provided by critical infrastructures, and hence it is important that they are reliable and robust. Two main approaches for gaining knowledge required for designing and improving critical infrastructures are reliability analysis and vulnerability analysis. The former analyses the ability of the system to perform its intended function; the latter analyses its inability to withstand strains and the effects of the consequent failures. The two approaches have similarities but also some differences with respect to what type of information they generate about the system. In this view, the main purpose of this paper is to discuss and contrast these approaches. To strengthen the discussion and exemplify its findings, a Monte Carlo-based reliability analysis and a vulnerability analysis are considered in their application to a relatively simple, but representative, system the IEEE RTS96 electric power test system. The exemplification reveals that reliability analysis provides a good picture of the system likely behaviour, but fails to capture a large portion of the high consequence scenarios, which are instead captured in the vulnerability analysis. Although these scenarios might be estimated to have small probabilities of occurrence, they should be identified, considered and treated cautiously, as probabilistic analyses should not be the only input to decision-making for the design and protection of critical infrastructures. The general conclusion that can be drawn from the findings of the example is that vulnerability analysis should be used to complement reliability studies, as well as other forms of probabilistic risk analysis. Measures should be sought for reducing both the vulnerability, i.e. improving the system ability to withstand strains and stresses, and the reliability, i.e. improving the likely behaviour

  2. Comparative analyses of seven technologies to facilitate the integration of fluctuating renewable energy sources

    DEFF Research Database (Denmark)

    Mathiesen, Brian Vad; Lund, Henrik

    2009-01-01

    An analysis of seven different technologies is presented. The technologies integrate fluctuating renewable energy sources (RES) such as wind power production into the electricity supply, and the Danish energy system is used as a case. Comprehensive hour-by-hour energy system analyses are conducted...... of a complete system meeting electricity, heat and transport demands, and including RES, power plants, and combined heat and power production (CHP) for district heating and transport technologies. In conclusion, the most fuel-efficient and least-cost technologies are identified through energy system...

  3. Gestion des risques

    CERN Document Server

    Louisot, Jean-Paul

    2009-01-01

    Depuis le début du lie siècle, la gestion des risques connaît une véritable révolution culturelle. Jusqu'alors fonction technique, centrée autour de l'achat de couverture d'assurances, elle est devenue une discipline managériale et transversale : une valise d'instruments que chaque manager doit connaître et appliquer quels que soient son domaine de compétence et ses missions au sein de l'organisation. En effet, la gestion des risques est une culture qui doit être assimilée par chacun des acteurs. C'est précisément l'ambition des 101 questions rassemblées dans cet ouvrage : apporter à chaque manager d'entreprise, de collectivité, d'établissement de santé..., des réponses claires au " pourquoi " et au " comment " : Comment identifier les risques ? Comment analyser les risques ? Quels sont les objectifs de la gestion des risques ? Une carte des risques pour quoi faire ? Pourquoi faut-il financer les risques ? Les entreprises ont-elles des responsabilités pénales ? En quoi consiste la gestion...

  4. Comparative analyses of chloroplast genome data representing nine green algae in Sphaeropleales (Chlorophyceae, Chlorophyta

    Directory of Open Access Journals (Sweden)

    Karolina Fučíková

    2016-06-01

    Full Text Available The chloroplast genomes of green algae are highly variable in their architecture. In this article we summarize gene content across newly obtained and published chloroplast genomes in Chlorophyceae, including new data from nine of species in Sphaeropleales (Chlorophyceae, Chlorophyta. We present genome architecture information, including genome synteny analysis across two groups of species. Also, we provide a phylogenetic tree obtained from analysis of gene order data for species in Chlorophyceae with fully sequenced chloroplast genomes. Further analyses and interpretation of the data can be found in “Chloroplast phylogenomic data from the green algal order Sphaeropleales (Chlorophyceae, Chlorophyta reveal complex patterns of sequence evolution” (Fučíková et al., In review [1].

  5. Droit des organisations internationales

    CERN Document Server

    Sorel, Jean-Marc; Ndior, Valère

    2013-01-01

    Cet ouvrage collectif offre aux enseignants et chercheurs en droit international, aux praticiens et aux étudiants, une analyse actualisée du droit des organisations internationales. Il dresse en cinq parties un tableau, illustré par des exemples variés, des problématiques que soulève le phénomène polymorphe d institutionnalisation de la société internationale. La première partie est consacrée au phénomène des « organisations internationales », sous l angle à la fois de l institutionnalisation progressive des relations internationales et de la difficulté à cerner une catégorie unifiée. La deuxième partie rend compte de la création, de la disparition et des mutations des organisations internationales, ici envisagées comme systèmes institutionnels et ordres juridiques dérivés. La troisième partie analyse l autonomie que l acquisition de la personnalité juridique et de privilèges et immunités, un organe administratif intégré, un personnel ou un budget propres confèrent aux organi...

  6. Analysis and development of spatial hp-refinement methods for solving the neutron transport equation; Analyse et developpement de methodes de raffinement hp en espace pour l'equation de transport des neutrons

    Energy Technology Data Exchange (ETDEWEB)

    Fournier, D.

    2011-10-10

    comparaison de ces deux estimateurs est faite sur des benchmarks dont on connait la solution exacte grace a des methodes de solutions manufacturees. On peut ainsi analyser le comportement des estimateurs au regard de la regularite de la solution. Grace a cette etude, une strategie de raffinement hp utilisant ces deux estimateurs est proposee et comparee a d'autres methodes rencontrees dans la litterature. L'ensemble des comparaisons est realise tant sur des cas simplifies ou l'on connait la solution exacte que sur des cas realistes issus de la physique des reacteurs. Ces methodes adaptatives permettent de reduire considerablement l'empreinte memoire et le temps de calcul. Afin d'essayer d'ameliorer encore ces deux aspects, on propose d'utiliser des maillages differents par groupe d'energie. En effet, l'allure spatiale du flux etant tres dependante du domaine energetique, il n'y a a priori aucune raison d'utiliser la meme decomposition spatiale. Une telle approche nous oblige a modifier les estimateurs initiaux afin de prendre en compte le couplage entre les differentes energies. L'etude de ce couplage est realisee de maniere theorique et des solutions numeriques sont proposees puis testees

  7. Determination of correction coefficients for quantitative analysis by mass spectrometry. Application to uranium impurities analysis; Recherche des coefficients de correction permettant l'analyse quantitative par spectrometrie de masse. Application a l'analyse d'impuretes dans l'uranium

    Energy Technology Data Exchange (ETDEWEB)

    Billon, J P [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes

    1970-07-01

    Some of basic principles in spark source mass spectrometry are recalled. It is shown how this method can lead to quantitative analysis when attention is paid to some theoretical aspects. A time constant relation being assumed between the analysed solid sample and the ionic beam it gives we determined experimental relative sensitivity factors for impurities in uranium matrix. Results being in fairly good agreement with: an unelaborate theory on ionization yield in spark-source use of theoretically obtained relative sensitivity factors in uranium matrix has been developed. (author) [French] Apres avoir rappele quelques principes fondamentaux regissant la spectrometrie de masse a etincelles, nous avons montre que moyennant un certain nombre de precautions, il etait possible d'utiliser cette methode en analyse quantitative. Ayant admis qu'il existait une relation constante dans le temps entre l'echantillon solide analyse et le faisceau ionique qui en est issu, nous avons d'abord entrepris de determiner des coefficients de correction experimentaux pour des matrices d'uranium. Les premiers resultats pratiques semblant en accord avec une theorie simple relative au rendement d'ionisation dans la source a etincelles, nous avons etudie la possibilite d'appliquer directement les coefficients theoriques ainsi definis, l'application etant toujours faite sur des matrices d'uranium. (auteur)

  8. En quoi les cartes mentales, appliquées à l’environnement littoral, aident-elles au recueil et à l’analyse des représentations spatiales ?

    Directory of Open Access Journals (Sweden)

    Servane Gueben-Venière

    2011-09-01

    Full Text Available Après avoir été principalement utilisées en géographie urbaine,  puis quelque peu mises de côté par les géographes, les cartes mentales font désormais l’objet d’un regain d’intérêt, en particulier dans le champ de la géographie de l’environnement. Appliquées à l’espace littoral et employées en complément de l’entretien, elles se révèlent être non seulement un bon outil de recueil des représentations spatiales, mais aussi une aide précieuse pour leur analyse. Cet article s’appuie sur l’exemple de l’utilisation des cartes mentales dans le poster scientifique Des ingénieurs de plus en plus « verts ». Évolution du regard des ingénieurs en charge de la gestion du littoral néerlandais, lauréat du concours organisé par le forum de l’École Doctorale de Géographie de Paris de 2011 (le poster est téléchargeable à partir de la rubrique Documents annexes.After having been mainly used in urban geography, then cast aside by the geographers, mental maps are now the object of renewed interest, particularly in the field of environmental geography. Applied to the coast, and used as a supplement to the interview, these maps are not only of great assistance in collecting spatial representations, but also helpful in analyzing them. This article uses the example of the integration of mental maps in the scientific poster “Des ingénieurs de plus en plus “verts”. Évolution du regard des ingénieurs en charge de la gestion du littoral néerlandais” ("Engineers are ‘greener and greener’. Evolution of the thinking of engineers in charge of Dutch coastal management", prize-winner of the competition organized by the Paris Doctoral School of Geography Forum in 2011.

  9. Der Zusammenhang von Partnermarktopportunitäten aus dem Freundeskreis und der Stabilität von Paarbeziehungen : Eine Analyse mit den Daten des Partnermarktsurvey

    OpenAIRE

    Häring, Armando

    2014-01-01

    "Der Beitrag analysiert den Zusammenhang zwischen Partnermarktoportunitäten aus dem Freundeskreis und der Stabilität von Paarbeziehungen. Unter Verwendung des theoretischen Konzepts der Theorie der Interaktionsgelegenheiten sowie von Annahmen der Austauschtheorie und der Familienökonomie, werden mögliche Zusammenhänge zwischen gemeinsamen Freundeskreisen mit dem Partner, Partnermarktgelegenheiten aus dem Freundeskreis (sex ratio) und der Stabilität von Paarbeziehungen diskutiert. Der Beitrag ...

  10. Comparative Analyses of Physics Candidates Scores in West African and National Examinations Councils

    Science.gov (United States)

    Utibe, Uduak James; Agah, John Joseph

    2015-01-01

    The study is a comparative analysis of physics candidates' scores in West African and National Examinations Councils. It also investigates influence of gender. Results of 480 candidates were randomly selected form three randomly selected Senior Science Colleges using the WASSCE and NECOSSCE computer printout sent to the schools, transformed using…

  11. Comparative Factor Analyses of the Personal Attributes Questionnaire and the Bem Sex-Role Inventory.

    Science.gov (United States)

    Antill, John K.; Cunningham, John D.

    1982-01-01

    Compared the Personal Attributes Questionnaire (PAQ) and the Bem Sex Role Inventory (BSRI) as measures of androgyny. Results showed that femininty (Concern for Others) and masculinity (Dominance) accounted for most of the variance, but for PAQ, clusters of male- and female-valued items (i.e., Extroversion and Insecurity) formed subsidiary factors.…

  12. Product analyses and kinetic studies on gas phase oxidation of the fuel additive ethyl tert-butyl ether and its products; Produktanalysen und Kinetikuntersuchungen der Gasphasenoxidation des Kraftstoffadditivs Ethyl-tert-butylether und seiner Produkte

    Energy Technology Data Exchange (ETDEWEB)

    Becker, K H; Thuener, L

    1997-04-01

    The widespread use of the additive ETBE in gasoline leads to an increased release of this compound into the atmosphere via evaporation or exhaust fumes. In order to determine the influence of this additive on trace gas cycles it is first necessary to carry out studies on the degradation mechanisms and pertinent kinetic properties of this substance. The aim of the present study was to examine the degradation mechanisms of the fuel additive t-butyl ethyl ether under atmospheric conditions. The reactions of the main degradation products (t-butyl formiate and t-butyl acetate, together ca. 80%) were also studied in order to obtain as complete a picture of the degradation paths as possible. This was to permit an assessment of the influence of ETBE and its products on tropospheric trace gas cycles and ozone formation. [Deutsch] Bei haeufigem Zusatz von ETBE in Benzin wird diese Verbindung durch Verdampfung oder als Abgas verstaerkt in die Atmosphaere abgegeben. Um den Einfluss des Additivs auf die Spurengas-Kreislaeufe zu bestimmen, sind daher Untersuchungen noetig, um die Abbau-Mechanismen und die zugehoerigen kinetischen Daten zu ermitteln. Das Ziel dieser Arbeit ist die Untersuchung der Abbaumechanismen des Kraftstoffadditivs t-Butylethylether unter atmosphaerischen Bedingungen. Fuer eine moeglichst vollstaendige Analyse des Abbauweges werden auch die Reaktionen der Hauptabbauprodukte (t-Butylformiat und t-Butylacetat, zusammen etwa 80%) untersucht. Dadurch soll der Einfluss auf troposphaerische Spurengas-Kreislaeufe und auf die Ozonbildung von ETBE und seinen Produkten abgeschaetzt werden. (orig./SR)

  13. Rôle des acteurs dans le processus d’élaboration de projets routiers. Analyse de l’approche opérationnelle et recherche de critères décisionnels.

    Directory of Open Access Journals (Sweden)

    Shahinaz Sayagh

    2008-08-01

    Full Text Available Depuis le stade des études préliminaires jusqu’à la réalisation des travaux, un projet routier fait l’objet de décisions successives (opportunité, budget, tracé…, selon une procédure progressive et réglementée. Cette succession de choix s’insère dans un faisceau de contraintes environnementales, techniques et financières. Ceci rend le processus décisionnel complexe, du fait notamment de la multiplicité des acteurs potentiellement impliqués. Dans ce contexte, la contribution de chercheurs peut consister à fournir des méthodes, permettant d’apporter un éclairage sur les conséquences potentielles en terme de développement durable, des décisions successives prises depuis la conception d’un projet routier jusqu’à sa réalisation. Dans cette perspective, une analyse des critères décisionnels propres à chacun des acteurs au sein du processus décisionnel, est nécessaire. L’objectif de cet article est d’analyser sur quels enjeux généraux reposent les critères décisionnels intervenant dans les différents choix successifs d’un projet routier. Il s’agit d’une part d’effectuer l’examen détaillé du processus décisionnel régi par des éléments factuels imposés par la réglementation, et d’autre part de mieux appréhender les critères non réglementaires, propres à chaque acteur sous la forme de témoignages. Sur la base de la synthèse réalisée, une discussion propose ensuite de mettre en perspective l’analyse effectuée au regard des enjeux environnementaux et de concertation. L’analyse montre la difficulté à définir une liste de critères décisionnels relatifs à la prise en compte des enjeux du développement durable. D’autre part, la réflexion menée met en lumière la meilleure prise en compte des enjeux environnementaux lorsqu’une démarche de concertation est menée en amont du projet, ce qui va au-delà du simple cadre réglementaire et reste à l’initiative de la ma

  14. Inactivité physique et nombre d'heures passées devant la télévision chez les adultes autochtones asthmatiques : analyse transversale de l'Enquête auprès des peuples autochtones

    Directory of Open Access Journals (Sweden)

    N. Doggett

    2015-01-01

    Full Text Available Contexte : Notre analyse visait à déterminer l'association entre l'asthme et le niveau d'activité physique ainsi qu'avec le nombre d'heures d'activités sédentaires chez les adultes autochtones et visait à comprendre l'influence de l'inactivité physique et du nombre d'heures d'activités sédentaires sur l'utilisation des soins de santé par les adultes autochtones asthmatiques. Méthodologie : Notre analyse a porté sur 20 953 répondants adultes de l'Enquête auprès des peuples autochtones de 2006. Nous avons considéré que les répondants étaient atteints d'asthme « actuel » s'ils avaient déclaré avoir reçu un diagnostic d'asthme de la part d'un médecin et s'ils avaient une ordonnance valide pour des médicaments contre l'asthme. Notre définition d'une activité physique insuffisante correspondait au fait de pratiquer moins de 3 heures d'activité physique modérée à intense par semaine, et notre définition d'un nombre élevé d'heures passées devant la télévision correspondait au fait de regarder la télévision pendant plus de 10 heures par semaine. Nous avons évalué l'utilisation des soins de santé à l'aide du nombre de consultations de professionnels de la santé et du nombre d'hospitalisations d'au moins une nuit. Résultats : Les adultes autochtones asthmatiques étaient plus susceptibles de déclarer un nombre élevé d'heures passées devant la télévision (RC = 1,16; IC : 1,11 à 1,22 et une activité physique insuffisante (RC = 1,15; IC : 1,10 à 1,20 que les non-asthmatiques. Les asthmatiques ayant déclaré un nombre élevé d'heures passées devant la télévision ont signalé plus de consultations de professionnels de la santé au cours des 12 derniers mois (RC = 2,59; IC : 2,34 à 2,87, plus d'hospitalisations d'au moins une nuit au cours de la dernière année (RC = 1,95; IC : 1,82 à 2,08 et plus d'hospitalisations d'au moins une nuit au cours des 5 dernières années (RC = 1,13; IC : 1,07 à 1

  15. Comparative clinical effectiveness of management strategies for sciatica: systematic review and network meta-analyses.

    Science.gov (United States)

    Lewis, Ruth A; Williams, Nefyn H; Sutton, Alex J; Burton, Kim; Din, Nafees Ud; Matar, Hosam E; Hendry, Maggie; Phillips, Ceri J; Nafees, Sadia; Fitzsimmons, Deborah; Rickard, Ian; Wilkinson, Clare

    2015-06-01

    There are numerous treatment approaches for sciatica. Previous systematic reviews have not compared all these strategies together. To compare the clinical effectiveness of different treatment strategies for sciatica simultaneously. Systematic review and network meta-analysis. We searched 28 electronic databases and online trial registries, along with bibliographies of previous reviews for comparative studies evaluating any intervention to treat sciatica in adults, with outcome data on global effect or pain intensity. Network meta-analysis methods were used to simultaneously compare all treatment strategies and allow indirect comparisons of treatments between studies. The study was funded by the UK National Institute for Health Research Health Technology Assessment program; there are no potential conflict of interests. We identified 122 relevant studies; 90 were randomized controlled trials (RCTs) or quasi-RCTs. Interventions were grouped into 21 treatment strategies. Internal and external validity of included studies was very low. For overall recovery as the outcome, compared with inactive control or conventional care, there was a statistically significant improvement following disc surgery, epidural injections, nonopioid analgesia, manipulation, and acupuncture. Traction, percutaneous discectomy, and exercise therapy were significantly inferior to epidural injections or surgery. For pain as the outcome, epidural injections and biological agents were significantly better than inactive control, but similar findings for disc surgery were not statistically significant. Biological agents were significantly better for pain reduction than bed rest, nonopioids, and opioids. Opioids, education/advice alone, bed rest, and percutaneous discectomy were inferior to most other treatment strategies; although these findings represented large effects, they were statistically equivocal. For the first time, many different treatment strategies for sciatica have been compared in the

  16. Comparative analyses of glycerotoxin expression unveil a novel structural organization of the bloodworm venom system.

    Science.gov (United States)

    Richter, Sandy; Helm, Conrad; Meunier, Frederic A; Hering, Lars; Campbell, Lahcen I; Drukewitz, Stephan H; Undheim, Eivind A B; Jenner, Ronald A; Schiavo, Giampietro; Bleidorn, Christoph

    2017-03-04

    We present the first molecular characterization of glycerotoxin (GLTx), a potent neurotoxin found in the venom of the bloodworm Glycera tridactyla (Glyceridae, Annelida). Within the animal kingdom, GLTx shows a unique mode of action as it can specifically up-regulate the activity of Ca v 2.2 channels (N-type) in a reversible manner. The lack of sequence information has so far hampered a detailed understanding of its mode of action. Our analyses reveal three ~3.8 kb GLTx full-length transcripts, show that GLTx represents a multigene family, and suggest it functions as a dimer. An integrative approach using transcriptomics, quantitative real-time PCR, in situ hybridization, and immunocytochemistry shows that GLTx is highly expressed exclusively in four pharyngeal lobes, a previously unrecognized part of the venom apparatus. Our results overturn a century old textbook view on the glycerid venom system, suggesting that it is anatomically and functionally much more complex than previously thought. The herein presented GLTx sequence information constitutes an important step towards the establishment of GLTx as a versatile tool to understand the mechanism of synaptic function, as well as the mode of action of this novel neurotoxin.

  17. Comparative brain transcriptomic analyses of scouting across distinct behavioural and ecological contexts in honeybees

    Science.gov (United States)

    Liang, Zhengzheng S.; Mattila, Heather R.; Rodriguez-Zas, Sandra L.; Southey, Bruce R.; Seeley, Thomas D.; Robinson, Gene E.

    2014-01-01

    Individual differences in behaviour are often consistent across time and contexts, but it is not clear whether such consistency is reflected at the molecular level. We explored this issue by studying scouting in honeybees in two different behavioural and ecological contexts: finding new sources of floral food resources and finding a new nest site. Brain gene expression profiles in food-source and nest-site scouts showed a significant overlap, despite large expression differences associated with the two different contexts. Class prediction and ‘leave-one-out’ cross-validation analyses revealed that a bee's role as a scout in either context could be predicted with 92.5% success using 89 genes at minimum. We also found that genes related to four neurotransmitter systems were part of a shared brain molecular signature in both types of scouts, and the two types of scouts were more similar for genes related to glutamate and GABA than catecholamine or acetylcholine signalling. These results indicate that consistent behavioural tendencies across different ecological contexts involve a mixture of similarities and differences in brain gene expression. PMID:25355476

  18. Comparative analyses of amplicon migration behavior in differing denaturing gradient gel electrophoresis (DGGE) systems

    Science.gov (United States)

    Thornhill, D. J.; Kemp, D. W.; Sampayo, E. M.; Schmidt, G. W.

    2010-03-01

    Denaturing gradient gel electrophoresis (DGGE) is commonly utilized to identify and quantify microbial diversity, but the conditions required for different electrophoretic systems to yield equivalent results and optimal resolution have not been assessed. Herein, the influence of different DGGE system configuration parameters on microbial diversity estimates was tested using Symbiodinium, a group of marine eukaryotic microbes that are important constituents of coral reef ecosystems. To accomplish this, bacterial clone libraries were constructed and sequenced from cultured isolates of Symbiodinium for the ribosomal DNA internal transcribed spacer 2 (ITS2) region. From these, 15 clones were subjected to PCR with a GC clamped primer set for DGGE analyses. Migration behaviors of the resulting amplicons were analyzed using a range of conditions, including variation in the composition of the denaturing gradient, electrophoresis time, and applied voltage. All tests were conducted in parallel on two commercial DGGE systems, a C.B.S. Scientific DGGE-2001, and the Bio-Rad DCode system. In this context, identical nucleotide fragments exhibited differing migration behaviors depending on the model of apparatus utilized, with fragments denaturing at a lower gradient concentration and applied voltage on the Bio-Rad DCode system than on the C.B.S. Scientific DGGE-2001 system. Although equivalent PCR-DGGE profiles could be achieved with both brands of DGGE system, the composition of the denaturing gradient and application of electrophoresis time × voltage must be appropriately optimized to achieve congruent results across platforms.

  19. Comparing sequencing assays and human-machine analyses in actionable genomics for glioblastoma.

    Science.gov (United States)

    Wrzeszczynski, Kazimierz O; Frank, Mayu O; Koyama, Takahiko; Rhrissorrakrai, Kahn; Robine, Nicolas; Utro, Filippo; Emde, Anne-Katrin; Chen, Bo-Juen; Arora, Kanika; Shah, Minita; Vacic, Vladimir; Norel, Raquel; Bilal, Erhan; Bergmann, Ewa A; Moore Vogel, Julia L; Bruce, Jeffrey N; Lassman, Andrew B; Canoll, Peter; Grommes, Christian; Harvey, Steve; Parida, Laxmi; Michelini, Vanessa V; Zody, Michael C; Jobanputra, Vaidehi; Royyuru, Ajay K; Darnell, Robert B

    2017-08-01

    To analyze a glioblastoma tumor specimen with 3 different platforms and compare potentially actionable calls from each. Tumor DNA was analyzed by a commercial targeted panel. In addition, tumor-normal DNA was analyzed by whole-genome sequencing (WGS) and tumor RNA was analyzed by RNA sequencing (RNA-seq). The WGS and RNA-seq data were analyzed by a team of bioinformaticians and cancer oncologists, and separately by IBM Watson Genomic Analytics (WGA), an automated system for prioritizing somatic variants and identifying drugs. More variants were identified by WGS/RNA analysis than by targeted panels. WGA completed a comparable analysis in a fraction of the time required by the human analysts. The development of an effective human-machine interface in the analysis of deep cancer genomic datasets may provide potentially clinically actionable calls for individual patients in a more timely and efficient manner than currently possible. NCT02725684.

  20. UniPrimer: A Web-Based Primer Design Tool for Comparative Analyses of Primate Genomes

    Directory of Open Access Journals (Sweden)

    Nomin Batnyam

    2012-01-01

    Full Text Available Whole genome sequences of various primates have been released due to advanced DNA-sequencing technology. A combination of computational data mining and the polymerase chain reaction (PCR assay to validate the data is an excellent method for conducting comparative genomics. Thus, designing primers for PCR is an essential procedure for a comparative analysis of primate genomes. Here, we developed and introduced UniPrimer for use in those studies. UniPrimer is a web-based tool that designs PCR- and DNA-sequencing primers. It compares the sequences from six different primates (human, chimpanzee, gorilla, orangutan, gibbon, and rhesus macaque and designs primers on the conserved region across species. UniPrimer is linked to RepeatMasker, Primer3Plus, and OligoCalc softwares to produce primers with high accuracy and UCSC In-Silico PCR to confirm whether the designed primers work. To test the performance of UniPrimer, we designed primers on sample sequences using UniPrimer and manually designed primers for the same sequences. The comparison of the two processes showed that UniPrimer was more effective than manual work in terms of saving time and reducing errors.

  1. Comparative analyses of diffusion coefficients for different extraction processes from thyme

    Directory of Open Access Journals (Sweden)

    Petrovic Slobodan S.

    2012-01-01

    Full Text Available This work was aimed to analyze kinetics and mass transfer phenomena for different extraction processes from thyme (Thymus vulgaris L. leaves. Different extraction processes with ethanol were studied: Soxhlet extraction and ultrasound-assisted batch extraction on the laboratory scale as well as pilot plant batch extraction with mixing. The extraction processes with ethanol were compared to the process of supercritical carbon dioxide extraction performed at 10 MPa and 40°C. Experimental data were analyzed by mathematical model derived from the Fick’s second law to determine and compare diffusion coefficients in the periods of constant and decreasing extraction rate. In the fast extraction period, values of diffusion coefficients were one to three orders of magnitude higher compared to those determined for the period of slow extraction. The highest diffusion coefficient was reported for the fast extraction period of supercritical fluid extraction. In the case of extraction processes with ethanol, ultrasound, stirring and extraction temperature increase enhanced mass transfer rate in the washing phase. On the other hand, ultrasound contributed the most to the increase of mass transfer rate in the period of slow extraction.

  2. Risk Analysis of Flare Flame-out Condition in a Gas Process Facility Analyse des risques des conditions d’extinction de torche au sein d’une installation de traitement de gaz

    Directory of Open Access Journals (Sweden)

    Zadakbar O.

    2011-02-01

    Full Text Available Flaring is a common method of disposal of flammable waste gases in the downstream industries. Flare flame out (flame lift-off or blow-outs often occurs causing toxic vapors to discharge. The toxic gases released may have hazardous effects on the surrounding environment. To study the effect of inhalation exposure of these toxic gases on human health, the four steps of the EPA (Environmental Protection Agency framework with the field data to quantify the cancer and non-cancer health risks are integrated in this paper. As a part of exposure assessment, gas dispersion modeling using AERMOD and UDM-PHAST is applied in two different conditions of normal flaring and flare flame out during a particular climate condition in Khangiran region. Recommendations to avoid flare flame out conditions are also presented here. Le torchage est un procédé courant d’élimination des gaz résiduaires inflammables dans les industries de traitement. L’extinction de la torche (par décollage ou soufflage de flamme provoque souvent une émission de vapeurs toxiques. Ces gaz toxiques libérés peuvent présenter des effets dangereux sur le milieu environnant. Pour étudier l’effet d’une exposition par inhalation de ces gaz toxiques sur la santé, cet article croise les quatre étapes de la démarche de l’EPA (Environmental Protection Agency, Agence de protection de l’environnement avec les données d’exploitation afin de quantifier le risque sanitaire cancérologique et non cancérologique. Dans le cadre de l’estimation d’exposition, une modélisation de dispersion des gaz utilisant AERMOD et UDM-PHAST est évaluée dans deux configurations différentes de torchage normal et d’extinction de torche à l’occasion de conditions climatiques particulières dans la région du Khangiran. L’article propose également des recommandations destinées à éviter les conditions d’une extinction de flamme de torche.

  3. Analyse des stratégies d’apprentissage dans une méthode d’apprentissage par problèmes : le cas d’étudiantes en soins infirmiers

    Directory of Open Access Journals (Sweden)

    Caroline Larue

    2009-09-01

    Full Text Available Plusieurs institutions d’enseignement supérieur ont adopté l’apprentissage par problèmes comme méthode pédagogique, mais peu d’études, à notre connaissance, se sont intéressées à décrire les stratégies utilisées par les étudiants dans un curriculum d’apprentissage par problèmes. Le but de cette recherche est justement l’étude de ces stratégies. L’analyse des verbatims obtenus auprès de 31 étudiantes1 de soins infirmiers a permis de dégager un ensemble de stratégies et d’en évaluer la fréquence. Les résultats suggèrent que les étudiantes utilisent davantage des stratégies de traitement en surface de l’information que des stratégies de traitement en profondeur malgré des indications voulant que l’utilisation d’une approche en profondeur soit associée à une meilleure réussite au cours.Several higher education institutions have adopted problem-based learning as an educational method. But, as far as we know, very few studies try to describe the strategies which are used by students in order to succeed in a problem-based learning context. The purpose of this research is to study those strategies. The analysis of the verbatim obtained from 31 nursing students uncovered the main strategies and their respective frequency. The results suggest that the students are more likely to use strategies based on surface treatment of the information than in-depth learning strategies. This preference is maintained even though they were told that in-depth learning strategies increase their academic achievements.

  4. Microhabitats utilisés par les alevins 0+ d'une communauté de cyprins rhéophiles : analyse de l'évolution de la communauté et des densités de population

    Directory of Open Access Journals (Sweden)

    BARAS E.

    1995-04-01

    Full Text Available L'évolution de l'occupation des microhabitats par les alevins de la communauté de cyprins rhéophiles de l'Ourthe a été étudiée au cours de l'été et de l'automne 1994 par échantillonnage ponctuel d'abondance (électrodes fixes prépositionnées, courant continu. 16155 poissons (10-75 mm appartenant à 15 espèces ont été recensés sur 78 sites d'échantillonnage de 2 m2 . Les espèces les plus représentées étaient Leuciscus cephalus, Leuciscus leuciscus et Chondrostoma nasus (respectivement 43,6 %, 20,7 % et 16,7 % des captures estivales. L'analyse factorielle des correspondances d'une matrice site x (espèce x taille met en évidence une subdivision progressive de la communauté au cours de l'été en espèces d'eau vive (B. barbus et L. leuciscus et d'eau lente, davantage associées à un couvert végétal (L. cephalus et C. nasus. La densité maximale observée (fin juin est de 1500 alevins (25 mm m-2, correspondant à une biomasse de 250 g m-2. Le modèle explicatif de la densité généré par analyse de régression multiple pas-à-pas explique 60,0 % de la variabilité de la densité par les variables vitesse de courant, température de l'eau et date d'échantillonnage, cette variable intégrant le concept de mortalité-dispersion au cours de la saison de croissance. Les implications de la méthodologie et des résultats présentés au plan de la gestion des écosystèmes lotiques sont brièvement discutés.

  5. Water and beverage consumption among children aged 4-13 years in France: analyses of INCA 2 (Étude Individuelle Nationale des Consommations Alimentaires 2006-2007) data.

    Science.gov (United States)

    Vieux, Florent; Maillot, Matthieu; Constant, Florence; Drewnowski, Adam

    2016-09-01

    To examine the consumption of plain water among children in France and compare total water intakes with guidelines issued by the European Food Safety Authority (EFSA). Nationally representative data were used to assess food, beverage and water consumption by sex, age group (4-8 years, 9-13 years), income-to-poverty ratio, eating occasion and location. Beverages were classified into nine groups: water (tap or bottled), milk, 100 % fruit juice, sodas, fruit drinks, hot beverages, sports drinks and flavoured waters. Total water volume in relation to energy intake (litres/kcal) was also examined. INCA 2 study (Étude Individuelle Nationale des Consommations Alimentaires 2006-2007). French children (n 835) aged 4-13 years. Total water intakes were accounted for by plain water (34 %), beverages (26 %) and food moisture (40 %). Plain water could be tap (18 %) or bottled (16 %). Older children drank more plain water than did younger children and boys drank more plain water than did girls. No socio-economic gradient for plain water consumption was observed. About 90 % of children did not meet the EFSA water intake recommendations. The daily water shortfall ranged from 367 to 594 ml/d. Water-to-energy ratio was 0·75-0·77 litres/1000 kcal (4184 kJ). Children drank milk at breakfast and plain water during lunch and dinner. Caloric beverages provided 10 % of dietary energy; consumption patterns varied by eating location. Total water intakes among young children in France were below EFSA-recommended levels. Analyses of beverage consumption patterns by eating occasion and location can help identify ways to increase water consumption among children.

  6. Comparative metagenomic, phylogenetic and physiological analyses of soil microbial communities across nitrogen gradients.

    Science.gov (United States)

    Fierer, Noah; Lauber, Christian L; Ramirez, Kelly S; Zaneveld, Jesse; Bradford, Mark A; Knight, Rob

    2012-05-01

    Terrestrial ecosystems are receiving elevated inputs of nitrogen (N) from anthropogenic sources and understanding how these increases in N availability affect soil microbial communities is critical for predicting the associated effects on belowground ecosystems. We used a suite of approaches to analyze the structure and functional characteristics of soil microbial communities from replicated plots in two long-term N fertilization experiments located in contrasting systems. Pyrosequencing-based analyses of 16S rRNA genes revealed no significant effects of N fertilization on bacterial diversity, but significant effects on community composition at both sites; copiotrophic taxa (including members of the Proteobacteria and Bacteroidetes phyla) typically increased in relative abundance in the high N plots, with oligotrophic taxa (mainly Acidobacteria) exhibiting the opposite pattern. Consistent with the phylogenetic shifts under N fertilization, shotgun metagenomic sequencing revealed increases in the relative abundances of genes associated with DNA/RNA replication, electron transport and protein metabolism, increases that could be resolved even with the shallow shotgun metagenomic sequencing conducted here (average of 75 000 reads per sample). We also observed shifts in the catabolic capabilities of the communities across the N gradients that were significantly correlated with the phylogenetic and metagenomic responses, indicating possible linkages between the structure and functioning of soil microbial communities. Overall, our results suggest that N fertilization may, directly or indirectly, induce a shift in the predominant microbial life-history strategies, favoring a more active, copiotrophic microbial community, a pattern that parallels the often observed replacement of K-selected with r-selected plant species with elevated N.

  7. Comparative analyses of reproductive structures in harvestmen (opiliones reveal multiple transitions from courtship to precopulatory antagonism.

    Directory of Open Access Journals (Sweden)

    Mercedes M Burns

    Full Text Available Explaining the rapid, species-specific diversification of reproductive structures and behaviors is a long-standing goal of evolutionary biology, with recent research tending to attribute reproductive phenotypes to the evolutionary mechanisms of female mate choice or intersexual conflict. Progress in understanding these and other possible mechanisms depends, in part, on reconstructing the direction, frequency and relative timing of phenotypic evolution of male and female structures in species-rich clades. Here we examine evolution of reproductive structures in the leiobunine harvestmen or "daddy long-legs" of eastern North America, a monophyletic group that includes species in which males court females using nuptial gifts and other species that are equipped for apparent precopulatory antagonism (i.e., males with long, hardened penes and females with sclerotized pregenital barriers. We used parsimony- and Bayesian likelihood-based analyses to reconstruct character evolution in categorical reproductive traits and found that losses of ancestral gift-bearing penile sacs are strongly associated with gains of female pregenital barriers. In most cases, both events occur on the same internal branch of the phylogeny. These coevolutionary changes occurred at least four times, resulting in clade-specific designs in the penis and pregenital barrier. The discovery of convergent origins and/or enhancements of apparent precopulatory antagonism among closely related species offers an unusual opportunity to investigate how major changes in reproductive morphology have occurred. We propose new hypotheses that attribute these enhancements to changes in ecology or life history that reduce the duration of breeding seasons, an association that is consistent with female choice, sexual conflict, and/or an alternative evolutionary mechanism.

  8. Thermo-economic analysis of recuperated Maisotsenko bottoming cycle using triplex air saturator: Comparative analyses

    International Nuclear Information System (INIS)

    Saghafifar, Mohammad; Omar, Amr; Erfanmoghaddam, Sepehr; Gadalla, Mohamed

    2017-01-01

    Highlights: • Proposing recuperated Maisotsenko bottoming cycle (RMBC) as a new combined cycle. • Introducing triplex air saturator for waste heat recovery application. • Conducting thermodynamic optimization to maximize RMBC thermal efficiency. • Conducting thermo-economic optimization to minimize RMBC cost of electricity. - Abstract: A recently recommended combined cycle power plant is to employ another gas turbine cycle for waste heat recovery as an air bottoming cycle (ABC). There are some studies conducted to improve ABC’s thermodynamic performance utilizing commonly power augmentation methods such as steam/water injection. In particular, it is proposed to employ Maisotsenko gas turbine cycle as a bottoming cycle, i.e. Maisotsenko bottoming cycle (MBC). Due to the promising performance of the MBC configuration, it is decided to investigate a recuperated MBC (RMBC) configuration by recommending the triplex air saturator. In this way, the air saturator consists of three sections. The first section is an indirect evaporative cooler while the other two sections are responsible for heat recovery from the topping and bottoming cycle turbines exhaust. In this paper, thermodynamic and thermo-economic analyses are carried out to study the main merits and demerits of RMBC against MBC configuration. Thermodynamic optimization results indicate that the maximum achievable efficiency for MBC and RMBC incorporation in a simple gas turbine power plant are 39.40% and 44.73%, respectively. Finally, thermo-economic optimization shows that the optimum levelized cost of electricity for MBC and RMBC power plants are 62.922 US$/MWh and 58.154 US$/MWh, respectively.

  9. Comparative Genomics Analyses Reveal Extensive Chromosome Colinearity and Novel Quantitative Trait Loci in Eucalyptus.

    Directory of Open Access Journals (Sweden)

    Fagen Li

    Full Text Available Dense genetic maps, along with quantitative trait loci (QTLs detected on such maps, are powerful tools for genomics and molecular breeding studies. In the important woody genus Eucalyptus, the recent release of E. grandis genome sequence allows for sequence-based genomic comparison and searching for positional candidate genes within QTL regions. Here, dense genetic maps were constructed for E. urophylla and E. tereticornis using genomic simple sequence repeats (SSR, expressed sequence tag (EST derived SSR, EST-derived cleaved amplified polymorphic sequence (EST-CAPS, and diversity arrays technology (DArT markers. The E. urophylla and E. tereticornis maps comprised 700 and 585 markers across 11 linkage groups, totaling at 1,208.2 and 1,241.4 cM in length, respectively. Extensive synteny and colinearity were observed as compared to three earlier DArT-based eucalypt maps (two maps with E. grandis × E. urophylla and one map of E. globulus and with the E. grandis genome sequence. Fifty-three QTLs for growth (10-56 months of age and wood density (56 months were identified in 22 discrete regions on both maps, in which only one colocalizaiton was found between growth and wood density. Novel QTLs were revealed as compared with those previously detected on DArT-based maps for similar ages in Eucalyptus. Eleven to 585 positional candidate genes were obained for a 56-month-old QTL through aligning QTL confidence interval with the E. grandis genome. These results will assist in comparative genomics studies, targeted gene characterization, and marker-assisted selection in Eucalyptus and the related taxa.

  10. Comparative Genomics Analyses Reveal Extensive Chromosome Colinearity and Novel Quantitative Trait Loci in Eucalyptus

    Science.gov (United States)

    Weng, Qijie; Li, Mei; Yu, Xiaoli; Guo, Yong; Wang, Yu; Zhang, Xiaohong; Gan, Siming

    2015-01-01

    Dense genetic maps, along with quantitative trait loci (QTLs) detected on such maps, are powerful tools for genomics and molecular breeding studies. In the important woody genus Eucalyptus, the recent release of E. grandis genome sequence allows for sequence-based genomic comparison and searching for positional candidate genes within QTL regions. Here, dense genetic maps were constructed for E. urophylla and E. tereticornis using genomic simple sequence repeats (SSR), expressed sequence tag (EST) derived SSR, EST-derived cleaved amplified polymorphic sequence (EST-CAPS), and diversity arrays technology (DArT) markers. The E. urophylla and E. tereticornis maps comprised 700 and 585 markers across 11 linkage groups, totaling at 1,208.2 and 1,241.4 cM in length, respectively. Extensive synteny and colinearity were observed as compared to three earlier DArT-based eucalypt maps (two maps with E. grandis × E. urophylla and one map of E. globulus) and with the E. grandis genome sequence. Fifty-three QTLs for growth (10–56 months of age) and wood density (56 months) were identified in 22 discrete regions on both maps, in which only one colocalizaiton was found between growth and wood density. Novel QTLs were revealed as compared with those previously detected on DArT-based maps for similar ages in Eucalyptus. Eleven to 585 positional candidate genes were obained for a 56-month-old QTL through aligning QTL confidence interval with the E. grandis genome. These results will assist in comparative genomics studies, targeted gene characterization, and marker-assisted selection in Eucalyptus and the related taxa. PMID:26695430

  11. Comparing Postural Stability Entropy Analyses to Differentiate Fallers and Non-fallers.

    Science.gov (United States)

    Fino, Peter C; Mojdehi, Ahmad R; Adjerid, Khaled; Habibi, Mohammad; Lockhart, Thurmon E; Ross, Shane D

    2016-05-01

    The health and financial cost of falls has spurred research to differentiate the characteristics of fallers and non-fallers. Postural stability has received much of the attention with recent studies exploring various measures of entropy. This study compared the discriminatory ability of several entropy methods at differentiating two paradigms in the center-of-pressure of elderly individuals: (1) eyes open (EO) vs. eyes closed (EC) and (2) fallers (F) vs. non-fallers (NF). Methods were compared using the area under the curve (AUC) of the receiver-operating characteristic curves developed from logistic regression models. Overall, multiscale entropy (MSE) and composite multiscale entropy (CompMSE) performed the best with AUCs of 0.71 for EO/EC and 0.77 for F/NF. When methods were combined together to maximize the AUC, the entropy classifier had an AUC of for 0.91 the F/NF comparison. These results suggest researchers and clinicians attempting to create clinical tests to identify fallers should consider a combination of every entropy method when creating a classifying test. Additionally, MSE and CompMSE classifiers using polar coordinate data outperformed rectangular coordinate data, encouraging more research into the most appropriate time series for postural stability entropy analysis.

  12. Parental conflict in birds: comparative analyses of offspring development, ecology and mating opportunities

    Science.gov (United States)

    Olson, V.A; Liker, A; Freckleton, R.P; Székely, T

    2007-01-01

    Parents often conflict over how much care to provide to their offspring. This conflict is expected to produce a negative relationship between male and female parental care, the strength of which may be mediated by both ecological and life-history variables. Previous studies have observed such trade-offs, but it is not known how generally they occur. Traditional views of sexual conflict place great importance on ecological factors in determining levels of parental care, whereas alternative views propose that the key determinant is mating opportunity. We carried out a broad-scale comparative study of parental conflict using 193 species from 41 families of birds. Using phylogenetic comparative analysis, we establish the generality of intersexual parental care conflict. We also show that parental conflict, as indicated by the disparity in care between the male and the female, depends on offspring development and mating opportunities, since in precocial species both males and females responded to increased mating opportunities. Altricial birds, however, failed to show these relationships. We also found little influence of breeding climate on parental conflict. Taken together, our results suggest that sexual conflict is a key element in the evolution of parental care systems. They also support the view that the major correlates of the intersexual conflict are mating opportunities for both sexes, rather than the breeding environment. PMID:18029303

  13. Simple Comparative Analyses of Differentially Expressed Gene Lists May Overestimate Gene Overlap.

    Science.gov (United States)

    Lawhorn, Chelsea M; Schomaker, Rachel; Rowell, Jonathan T; Rueppell, Olav

    2018-04-16

    Comparing the overlap between sets of differentially expressed genes (DEGs) within or between transcriptome studies is regularly used to infer similarities between biological processes. Significant overlap between two sets of DEGs is usually determined by a simple test. The number of potentially overlapping genes is compared to the number of genes that actually occur in both lists, treating every gene as equal. However, gene expression is controlled by transcription factors that bind to a variable number of transcription factor binding sites, leading to variation among genes in general variability of their expression. Neglecting this variability could therefore lead to inflated estimates of significant overlap between DEG lists. With computer simulations, we demonstrate that such biases arise from variation in the control of gene expression. Significant overlap commonly arises between two lists of DEGs that are randomly generated, assuming that the control of gene expression is variable among genes but consistent between corresponding experiments. More overlap is observed when transcription factors are specific to their binding sites and when the number of genes is considerably higher than the number of different transcription factors. In contrast, overlap between two DEG lists is always lower than expected when the genetic architecture of expression is independent between the two experiments. Thus, the current methods for determining significant overlap between DEGs are potentially confounding biologically meaningful overlap with overlap that arises due to variability in control of expression among genes, and more sophisticated approaches are needed.

  14. Comparing EFT and Exact One-Loop Analyses of Non-Degenerate Stops

    CERN Document Server

    Drozd, Aleksandra; Quevillon, Jeremie; You, Tevong

    2015-01-01

    We develop a universal approach to the one-loop effective field theory (EFT) using the Covariant Derivative Expansion (CDE) method. We generalise previous results to include broader classes of UV models, showing how expressions previously obtained assuming degenerate heavy-particle masses can be extended to non-degenerate cases. We apply our method to the general MSSM with non-degenerate stop squarks, illustrating our approach with calculations of the coefficients of dimension-6 operators contributing to the $hgg$ and $h\\gamma\\gamma$ couplings, and comparing with exact calculations of one-loop Feynman diagrams. We then use present and projected future sensitivities to these operator coefficients to obtain present and possible future indirect constraints on stop masses. The current sensitivity is already comparable to that of direct LHC searches, and future FCC-ee measurements could be sensitive to stop masses above a TeV. The universality of our one-loop EFT approach facilitates extending these constraints to...

  15. Comparative Omics and Trait Analyses of Marine Pseudoalteromonas Phages Advance the Phage OTU Concept

    Directory of Open Access Journals (Sweden)

    Melissa B. Duhaime

    2017-07-01

    considered viral niches, while host ranges and infection efficiencies are tracked as viral traits. Quantitative host range assays revealed conserved traits within virus OTUs that break down between OTUs, suggesting the defined units capture niche and fitness differentiation. Together these analyses provide a foundation for model system-based hypothesis testing that will improve our understanding of marine copiotrophs, as well as phage–host interactions on the ocean particles and aggregates where Pseudoalteromonas thrive.

  16. Development of the control assembly pattern and dynamic analysis of the generation IV large gas-cooled fast reactor (GFR); Developpement du design d'un assemblage de controle et analyse dynamique des reacteurs a neutrons rapides de quatrieme generation refroidis au gaz

    Energy Technology Data Exchange (ETDEWEB)

    Girardin, G.

    2009-07-09

    modeles neutroniques 2D et 3D du coeur du reacteur ont ete crees, bases sur le schema de calculs de reference ERANOS-2.0/ERALIB1. Pour l'analyse thermo-hydraulique, le code COPERNIC du CEA a ete utilise. Le travail de design a ete poursuivi par l'etude d'un schema de l'implantation des assemblages de controle (nombre et position dans le coeur). Des etudes detaillees de neutronique ont reveles l'existence de grands effets d'interaction entre les AC, appeles effets d'ombre/d'anti-ombre, conduisant a une amplification/reduction de l'antireactivite des AC. Les interactions entre les barreaux absorbants a l'interieur d'un AC, ainsi qu'entre les AC eux-memes, ont ete investiguees dans le detail, dans le but d'optimiser l'efficacite des AC (en terme de la fraction d'absorbant et la minimisation des effets d'heterogeneite associes). Resultant d'investigations detaillees, le diametre des pastilles absorbantes a ete choisi de maniere a minimiser l'influence 'barreau-a-barreau' a l'interieur de l'assemblage. En particulier, une partie centrale de l'assemblage a ete concue sans aucun barreau absorbant (zone remplie d'helium statique). Par ce biais, une reduction, a 13%, des effets d'heterogeneite, a ete obtenue. Les investigations neutroniques effectuees pour le coeur RNR-G de reference ('2004-Coeur'), specialement, celles liees a l'Etude des interactions entre les AC, ont directement contribue au nouveau design du coeur ('2007-Coeur'). Le rapport hauteur sur diametre a ete augmente a 0.6, compare a la valeur de 0.3 pour le coeur de reference. Pendant la troisieme phase, des modeles couples et detailles, cinetiques 3D et thermohydrauliques 1D, ont ete developpes pour le coeur RNR-G; le but etait d'arriver a une comprehension, en profondeur, du comportement 3D du coeur pendant des transitoires induits par le mouvement d

  17. THE ECONOMIC STRUCTURES IN THE ROMANIAN REGIONS AND COUNTIES AND THE EU MEMBER STATES. COMPARATIVE ANALYSES.

    Directory of Open Access Journals (Sweden)

    Marioara, IORDAN

    2014-03-01

    Full Text Available Bridging the gap between countries, and thus decresing poverty, is the greatest challenge of European countries in the context of the European social cohesion. The risk of future economic difficulties caused by the size of budget deficits is beared by the funds to be allocated to social inclusion in the EU and the EU member countries. They will be concerned in the post-crisis period with aligning the requirements of progress, of poverty reduction, but also of ensuring the sustainability of public finances. For Romania, cohesion is particularly important as most regions show significant differences as compared to the EU average and the national average. This group also includes the South Muntenia Region, which has many advantages for faster progress and to be able to exploit the opportunities offered by the implementation of the Europe 2020 strategy.

  18. Comparative analyses suggest that information transfer promoted sociality in male bats in the temperate zone.

    Science.gov (United States)

    Safi, Kamran; Kerth, Gerald

    2007-09-01

    The evolution of sociality is a central theme in evolutionary biology. The vast majority of bats are social, which has been explained in terms of the benefits of communal breeding. However, the causes for segregated male groups remain unknown. In a comparative study, we tested whether diet and morphological adaptations to specific foraging styles, two factors known to influence the occurrence of information transfer, can predict male sociality. Our results suggest that the species most likely to benefit from information transfer--namely, those preying on ephemeral insects and with morphological adaptations to feeding in open habitat--are more likely to form male groups. Our findings also indicate that solitary life was the ancestral state of males and sociality evolved in several lineages. Beyond their significance for explaining the existence of male groups in bats, our findings highlight the importance of information transfer in the evolution of animal sociality.

  19. Comparative analyses of laccase-catalyzed amination reactions for production of novel β-lactam antibiotics.

    Science.gov (United States)

    Mikolasch, Annett; Manda, Katrin; Schlüter, Rabea; Lalk, Michael; Witt, Sabine; Seefeldt, Simone; Hammer, Elke; Schauer, Frieder; Jülich, Wolf-Dieter; Lindequist, Ulrike

    2012-01-01

    Seven novel β-lactam antibiotics with activities against Gram-positive bacterial strains, among them methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci, were synthesized by amination of 2,5-dihydroxyphenylacetic acid in usable yields (30-60%). These products protected mice against an infection with S. aureus lethal to the control animals. The results show the usefulness of laccase for the synthesis of potential new antibiotics, in addition to the interdependence of the laccase substrates, the amino coupling partners, and the product formation, yield, and activity. The syntheses of β-lactam antibiotics with 2,5-dihydroxyaromatic acid substructures (para-substituted) are then compared with those of 3,4-dihydroxyaromatic acid substructures (ortho-substituted). Para-substituted laccase substrates were better reaction partners in these syntheses than ortho-substituted compounds. Copyright © 2012 International Union of Biochemistry and Molecular Biology, Inc.

  20. Comparative analyses of the internal radiation exposures due to food chain pathway using food III code

    International Nuclear Information System (INIS)

    Choi, Yong Ho; Chung, Kyu Hoi; Kim, Jin Kyu; Lee, Jeong Ho

    1988-01-01

    In order to develop a food-chain computer code suitable to the environmental conditions of Korea, the FOOD III code was partially modified. The execution results for Korean male-adult were compared to those from the Canadian version of FOOD III to deduce a more realistic approach in dose assessment. The amounts of Mn-54, Co-50, Co-60, I-131 and I-132 released from Kori unit 1 in 1984 were used as the source terms for the sample calculation. The maximum atmospheric dispersion factor(X/Q) value on the site boundary was applied. Through the code modification, organ doses decreased by about 20∼70% and the effective committed dose equivalent by about 40% to be 7.935x10 -6 Sv/y which is 0.16% of the ICRP limit, 5x10 -3 Sv/y. (Author)

  1. Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires' disease.

    Science.gov (United States)

    Gomez-Valero, Laura; Rusniok, Christophe; Rolando, Monica; Neou, Mario; Dervins-Ravault, Delphine; Demirtas, Jasmin; Rouy, Zoe; Moore, Robert J; Chen, Honglei; Petty, Nicola K; Jarraud, Sophie; Etienne, Jerome; Steinert, Michael; Heuner, Klaus; Gribaldo, Simonetta; Médigue, Claudine; Glöckner, Gernot; Hartland, Elizabeth L; Buchrieser, Carmen

    2014-01-01

    The genus Legionella comprises over 60 species. However, L. pneumophila and L. longbeachae alone cause over 95% of Legionnaires’ disease. To identify the genetic bases underlying the different capacities to cause disease we sequenced and compared the genomes of L. micdadei, L. hackeliae and L. fallonii (LLAP10), which are all rarely isolated from humans. We show that these Legionella species possess different virulence capacities in amoeba and macrophages, correlating with their occurrence in humans. Our comparative analysis of 11 Legionella genomes belonging to five species reveals highly heterogeneous genome content with over 60% representing species-specific genes; these comprise a complete prophage in L. micdadei, the first ever identified in a Legionella genome. Mobile elements are abundant in Legionella genomes; many encode type IV secretion systems for conjugative transfer, pointing to their importance for adaptation of the genus. The Dot/Icm secretion system is conserved, although the core set of substrates is small, as only 24 out of over 300 described Dot/Icm effector genes are present in all Legionella species. We also identified new eukaryotic motifs including thaumatin, synaptobrevin or clathrin/coatomer adaptine like domains. Legionella genomes are highly dynamic due to a large mobilome mainly comprising type IV secretion systems, while a minority of core substrates is shared among the diverse species. Eukaryotic like proteins and motifs remain a hallmark of the genus Legionella. Key factors such as proteins involved in oxygen binding, iron storage, host membrane transport and certain Dot/Icm substrates are specific features of disease-related strains.

  2. Un développement urbain durable et socialement inclusif est-il possible dans le contexte de fragmentation socio-spatiale des métropoles des pays émergents? Réflexions à partir des cas de Recife (Brésil et de Chennai (Inde

    Directory of Open Access Journals (Sweden)

    Carrière Jean-Paul

    2016-12-01

    Full Text Available Dans un contexte globalisé, le développement de villes socialement durables et inclusives implique de nombreux défis contradictoires. L’analyse comparée des cas de Chennai, en Inde, et de Recife, au Brésil, montre qu’au-delà des spécificités de ces métropoles, nous retrouvons des processus de fragmentation socio-spatiale comparables et un réel décalage entre un discours sur l’insertion sociale et des pratiques urbanistiques orientées par la quête d’attractivité, qui se soldent par l’accentuation des inégalités. Ces contradictions renvoient à des conflits entre planification stratégique, jeu des forces des marchés immobilier et foncier, et attentes des populations. L’analyse de ces contradictions invite à repenser l’articulation de la dialectique local/global et à s’interroger sur l’effectivité du « droit à la ville » dans les sociétés de pays émergents. La comparaison développée dans cet article s’appuie sur des recherches menées à Recife dans un premier temps au début de la décennie en cours, puis plus récemment à Chennai.

  3. The comparative analyses of different diagnostic approaches in detection of gastroesophageal reflux disease in children.

    Directory of Open Access Journals (Sweden)

    Nina Ristic

    Full Text Available The aim of this study was to compare the different diagnostic approaches in detection of gastroesophageal reflux disease in children presented with symptoms suggesting gastroesophageal reflux disease.The study design was cross sectional. The study retrospectively included all children who underwent combined multiple intraluminal impedance and pH (pH-MII monitoring due to gastrointestinal and/or extraesophageal symptoms suggesting gastroesophageal reflux disease at University Children's Hospital in Belgrade, from July 2012 to July 2016.A total of 218 (117 boys/101 girls, mean age 6.7 years (range 0.06-18.0 years, met the inclusion criteria. Gastroesophageal reflux disease was found in 128 of 218 children (57.4% by pH-MII and in 76 (34.1% children by pH metry alone. Using pH-MII monitoring as gold standard, sensitivity of pH-metry was lowest in infants (22.9%, with tendency to increase in older age groups (reaching 76.4% in children ≥ 9 years. The sensitivity of pH-metry alone in children with extraesophageal symptoms was 38.1%, while the sensitivity of pH-metry in children with gastrointestinal symptoms was 63.8%. Reflux esophagitis was identified in 31 (26.1% of 119 children who underwent endoscopy. Logistic regression analysis showed that best predictors of endoscopic reflux esophagitis are the longest acid episode (OR = 1.52, p<0.05 and DeMeester reflux composite score (OR = 3.31, p<0.05. The significant cutoff values included DeMeester reflux composite score ≥ 29 (AUC 0.786, CI 0.695-0.877, p<0.01 and duration of longest acid reflux ≥ 18 minutes (AUC 0.784, CI 0.692-0.875, p<0.01.The results of our study suggested that compared with pH-metry alone, pH-MII had significantly higher detection rate of gastroesophageal reflux disease, especially in infants. Our findings also showed that pH-MII parameters correlated significantly with the endoscopically confirmed erosive esophagitis.

  4. Mixed Approach Retrospective Analyses of Suicide and Suicidal Ideation for Brand Compared with Generic Central Nervous System Drugs.

    Science.gov (United States)

    Cheng, Ning; Rahman, Md Motiur; Alatawi, Yasser; Qian, Jingjing; Peissig, Peggy L; Berg, Richard L; Page, C David; Hansen, Richard A

    2018-04-01

    Several different types of drugs acting on the central nervous system (CNS) have previously been associated with an increased risk of suicide and suicidal ideation (broadly referred to as suicide). However, a differential association between brand and generic CNS drugs and suicide has not been reported. This study compares suicide adverse event rates for brand versus generic CNS drugs using multiple sources of data. Selected examples of CNS drugs (sertraline, gabapentin, zolpidem, and methylphenidate) were evaluated via the US FDA Adverse Event Reporting System (FAERS) for a hypothesis-generating study, and then via administrative claims and electronic health record (EHR) data for a more rigorous retrospective cohort study. Disproportionality analyses with reporting odds ratios and 95% confidence intervals (CIs) were used in the FAERS analyses to quantify the association between each drug and reported suicide. For the cohort studies, Cox proportional hazards models were used, controlling for demographic and clinical characteristics as well as the background risk of suicide in the insured population. The FAERS analyses found significantly lower suicide reporting rates for brands compared with generics for all four studied products (Breslow-Day P brand CNS drugs in FAERS and adjusted retrospective cohort analyses remained significant only for sertraline. However, even for sertraline, temporal confounding related to the close proximity of black box warnings and generic availability is possible. Additional analyses in larger data sources with additional drugs are needed.

  5. Comparative physiological and proteomic analyses of poplar (Populus yunnanensis plantlets exposed to high temperature and drought.

    Directory of Open Access Journals (Sweden)

    Xiong Li

    Full Text Available Plantlets of Populus yunnanensis Dode were examined in a greenhouse for 48 h to analyze their physiological and proteomic responses to sustained heat, drought, and combined heat and drought. Compared with the application of a single stress, simultaneous treatment with both stresses damaged the plantlets more heavily. The plantlets experienced two apparent response stages under sustained heat and drought. During the first stage, malondialdehyde and reactive oxygen species (ROS contents were induced by heat, but many protective substances, including antioxidant enzymes, proline, abscisic acid (ABA, dehydrin, and small heat shock proteins (sHSPs, were also stimulated. The plants thus actively defended themselves against stress and exhibited few pathological morphological features, most likely because a new cellular homeostasis was established through the collaborative operation of physiological and proteomic responses. During the second stage, ROS homeostasis was overwhelmed by substantial ROS production and a sharp decline in antioxidant enzyme activities, while the synthesis of some protective elements, such as proline and ABA, was suppressed. As a result, photosynthetic levels in P. yunnanensis decreased sharply and buds began to die, despite continued accumulation of sHSPs and dehydrin. This study supplies important information about the effects of extreme abiotic environments on woody plants.

  6. Comparative analyses reveal high levels of conserved colinearity between the finger millet and rice genomes.

    Science.gov (United States)

    Srinivasachary; Dida, Mathews M; Gale, Mike D; Devos, Katrien M

    2007-08-01

    Finger millet is an allotetraploid (2n = 4x = 36) grass that belongs to the Chloridoideae subfamily. A comparative analysis has been carried out to determine the relationship of the finger millet genome with that of rice. Six of the nine finger millet homoeologous groups corresponded to a single rice chromosome each. Each of the remaining three finger millet groups were orthologous to two rice chromosomes, and in all the three cases one rice chromosome was inserted into the centromeric region of a second rice chromosome to give the finger millet chromosomal configuration. All observed rearrangements were, among the grasses, unique to finger millet and, possibly, the Chloridoideae subfamily. Gene orders between rice and finger millet were highly conserved, with rearrangements being limited largely to single marker transpositions and small putative inversions encompassing at most three markers. Only some 10% of markers mapped to non-syntenic positions in rice and finger millet and the majority of these were located in the distal 14% of chromosome arms, supporting a possible correlation between recombination and sequence evolution as has previously been observed in wheat. A comparison of the organization of finger millet, Panicoideae and Pooideae genomes relative to rice allowed us to infer putative ancestral chromosome configurations in the grasses.

  7. New perspectives on host-parasite interplay by comparative transcriptomic and proteomic analyses of Schistosoma japonicum.

    Directory of Open Access Journals (Sweden)

    Feng Liu

    2006-04-01

    Full Text Available Schistosomiasis remains a serious public health problem with an estimated 200 million people infected in 76 countries. Here we isolated ~ 8,400 potential protein-encoding cDNA contigs from Schistosoma japonicum after sequencing circa 84,000 expressed sequence tags. In tandem, we undertook a high-throughput proteomics approach to characterize the protein expression profiles of a number of developmental stages (cercariae, hepatic schistosomula, female and male adults, eggs, and miracidia and tissues at the host-parasite interface (eggshell and tegument by interrogating the protein database deduced from the contigs. Comparative analysis of these transcriptomic and proteomic data, the latter including 3,260 proteins with putative identities, revealed differential expression of genes among the various developmental stages and sexes of S. japonicum and localization of putative secretory and membrane antigens, enzymes, and other gene products on the adult tegument and eggshell, many of which displayed genetic polymorphisms. Numerous S. japonicum genes exhibited high levels of identity with those of their mammalian hosts, whereas many others appeared to be conserved only across the genus Schistosoma or Phylum Platyhelminthes. These findings are expected to provide new insights into the pathophysiology of schistosomiasis and for the development of improved interventions for disease control and will facilitate a more fundamental understanding of schistosome biology, evolution, and the host-parasite interplay.

  8. Comparative genomic analyses of transport proteins encoded within the genomes of Leptospira species.

    Science.gov (United States)

    Buyuktimkin, Bora; Saier, Milton H

    2015-11-01

    Select species of the bacterial genus Leptospira are causative agents of leptospirosis, an emerging global zoonosis affecting nearly one million people worldwide annually. We examined two Leptospira pathogens, Leptospira interrogans serovar Lai str. 56601 and Leptospira borgpetersenii serovar Hardjo-bovis str. L550, as well as the free-living leptospiral saprophyte, Leptospira biflexa serovar Patoc str. 'Patoc 1 (Ames)'. The transport proteins of these leptospires were identified and compared using bioinformatics to gain an appreciation for which proteins may be related to pathogenesis and saprophytism. L. biflexa possesses a disproportionately high number of secondary carriers for metabolite uptake and environmental adaptability as well as an increased number of inorganic cation transporters providing ionic homeostasis and effective osmoregulation in a rapidly changing environment. L. interrogans and L. borgpetersenii possess far fewer transporters, but those that they have are remarkably similar, with near-equivalent representation in most transporter families. These two Leptospira pathogens also possess intact sphingomyelinases, holins, and virulence-related outer membrane porins. These virulence-related factors, in conjunction with decreased transporter substrate versatility, indicate that pathogenicity was accompanied by progressively narrowing ecological niches and the emergence of a limited set of proteins responsible for host invasion. The variability of host tropism and mortality rates by infectious leptospires suggests that small differences in individual sets of proteins play important physiological and pathological roles. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. Comparative analyses of transport proteins encoded within the genomes of Leptospira species.

    Science.gov (United States)

    Buyuktimkin, Bora; Saier, Milton H

    2016-09-01

    Select species of the bacterial genus Leptospira are causative agents of leptospirosis, an emerging global zoonosis affecting nearly one million people worldwide annually. We examined two Leptospira pathogens, Leptospira interrogans serovar Lai str. 56601 and Leptospira borgpetersenii serovar Hardjo-bovis str. L550, as well as the free-living leptospiral saprophyte, Leptospira biflexa serovar Patoc str. 'Patoc 1 (Ames)'. The transport proteins of these leptospires were identified and compared using bioinformatics to gain an appreciation for which proteins may be related to pathogenesis and saprophytism. L. biflexa possesses a disproportionately high number of secondary carriers for metabolite uptake and environmental adaptability as well as an increased number of inorganic cation transporters providing ionic homeostasis and effective osmoregulation in a rapidly changing environment. L. interrogans and L. borgpetersenii possess far fewer transporters, but those that they all have are remarkably similar, with near-equivalent representation in most transporter families. These two Leptospira pathogens also possess intact sphingomyelinases, holins, and virulence-related outer membrane porins. These virulence-related factors, in conjunction with decreased transporter substrate versatility, indicate that pathogenicity arose in Leptospira correlating to progressively narrowing ecological niches and the emergence of a limited set of proteins responsible for host invasion. The variability of host tropism and mortality rates by infectious leptospires suggests that small differences in individual sets of proteins play important physiological and pathological roles. Copyright © 2016. Published by Elsevier Ltd.

  10. Comparative Analyses on OPR1000 Steam Generator Tube Rupture Event Emergency Operational Guideline

    International Nuclear Information System (INIS)

    Lee, Sang Won; Bae, Yeon Kyoung; Kim, Hyeong Teak

    2006-01-01

    The Steam Generator Tube Rupture (SGTR) event is one of the important scenarios in respect to the radiation release to the environment. When the SGTR occurs, containment integrity is not effective because of the direct bypass of containment via the ruptured steam generator to the MSSV and MSADV. To prevent this path, the Emergency Operational Guideline of OPR1000 indicates the use of Turbine Bypass Valves (TBVs) as an effective means to depressurize the main steam line and prevent the lifting of MSSV. However, the TBVs are not operable when the offsite power is not available (LOOP). In this situation, the RCS cool-down is achieved by opening the both intact and ruptured SG MSADV. But this action causes the large amount of radiation release to the environment. To minimize the radiation release to the environment, KSNP EOG adopts the improved strategy when the SGTR concurrently with LOOP is occurred. However, these procedures show some duplicated procedure and branch line that might confusing the operator for optimal recovery action. So, in this paper, the comparative analysis on SGTR and SGTR with LOOP is performed and optimized procedure is proposed

  11. Comparative analyses of the bacterial community of hydrothermal deposits and seafloor sediments across Okinawa Trough

    Science.gov (United States)

    Wang, Long; Yu, Min; Liu, Yan; Liu, Jiwen; Wu, Yonghua; Li, Li; Liu, Jihua; Wang, Min; Zhang, Xiao-Hua

    2018-04-01

    As an ideal place to study back-arc basins and hydrothermal eco-system, Okinawa Trough has attracted the interests of scientists for decades. However, there are still no in-depth studies targeting the bacterial community of the seafloor sediments and hydrothermal deposits in Okinawa Trough. In the present study, we reported the bacterial community of the surface deposits of a newly found hydrothermal field in the southern Okinawa Trough, and the horizontal and vertical variation of bacterial communities in the sediments of the northern Okinawa Trough. The hydrothermal deposits had a relatively high 16S rRNA gene abundance but low bacterial richness and diversity. Epsilonproteobacteria and Bacteroidetes were predominant in hydrothermal deposits whereas Deltaproteobacteria, Gammaproteobacteria and Chloroflexi were abundant across all samples. The bacterial distribution in the seafloor of Okinawa Trough was significantly correlated to the content of total nitrogen, and had consistent relationship with total carbon. Gradual changes of sulfur-oxidizing bacteria were found with the distance away from hydrothermal fields, while the hydrothermal activity did not influence the distribution of the major clades of sulfate-reducing bacteria. Higher abundance of the sulfur cycle related genes (aprA and dsrB), and lower abundance of the bacterial ammonia-oxidizing related gene (amoA) were quantified in hydrothermal deposits. In addition, the present study also compared the inter-field variation of Epsilonproteobacteria among multi-types of hydrothermal vents, revealing that the proportion and diversity of this clade were quite various.

  12. Agriproteomics of Bread Wheat: Comparative Proteomics and Network Analyses of Grain Size Variation.

    Science.gov (United States)

    Dawkar, Vishal V; Dholakia, Bhushan B; Gupta, Vidya S

    2015-07-01

    Agriproteomics signifies the merging of agriculture research and proteomics systems science and is impacting plant research and societal development. Wheat is a frequently consumed foodstuff, has highly variable grain size that in effect contributes to wheat grain yield and the end-product quality. Very limited information is available on molecular basis of grain size due to complex multifactorial nature of this trait. Here, using liquid chromatography-mass spectrometry, we investigated the proteomics profiles from grains of wheat genotypes, Rye selection 111 (RS111) and Chinese spring (CS), which differ in their size. Significant differences in protein expression were found, including 33 proteins uniquely present in RS111 and 32 only in CS, while 54 proteins were expressed from both genotypes. Among differentially expressed proteins, 22 were upregulated, while 21 proteins were downregulated in RS111 compared to CS. Functional classification revealed their role in energy metabolism, seed storage, stress tolerance and transcription. Further, protein interactive network analysis was performed to predict the targets of identified proteins. Significantly different interactions patterns were observed between these genotypes with detection of proteins such as Cyp450, Sus2, and WRKY that could potentially affect seed size. The present study illustrates the potentials of agriproteomics as a veritable new frontier of plant omics research.

  13. The complete chloroplast genome sequence of Dodonaea viscosa: comparative and phylogenetic analyses.

    Science.gov (United States)

    Saina, Josphat K; Gichira, Andrew W; Li, Zhi-Zhong; Hu, Guang-Wan; Wang, Qing-Feng; Liao, Kuo

    2018-02-01

    The plant chloroplast (cp) genome is a highly conserved structure which is beneficial for evolution and systematic research. Currently, numerous complete cp genome sequences have been reported due to high throughput sequencing technology. However, there is no complete chloroplast genome of genus Dodonaea that has been reported before. To better understand the molecular basis of Dodonaea viscosa chloroplast, we used Illumina sequencing technology to sequence its complete genome. The whole length of the cp genome is 159,375 base pairs (bp), with a pair of inverted repeats (IRs) of 27,099 bp separated by a large single copy (LSC) 87,204 bp, and small single copy (SSC) 17,972 bp. The annotation analysis revealed a total of 115 unique genes of which 81 were protein coding, 30 tRNA, and four ribosomal RNA genes. Comparative genome analysis with other closely related Sapindaceae members showed conserved gene order in the inverted and single copy regions. Phylogenetic analysis clustered D. viscosa with other species of Sapindaceae with strong bootstrap support. Finally, a total of 249 SSRs were detected. Moreover, a comparison of the synonymous (Ks) and nonsynonymous (Ka) substitution rates in D. viscosa showed very low values. The availability of cp genome reported here provides a valuable genetic resource for comprehensive further studies in genetic variation, taxonomy and phylogenetic evolution of Sapindaceae family. In addition, SSR markers detected will be used in further phylogeographic and population structure studies of the species in this genus.

  14. Comparative transcriptomic analyses of differentially expressed genes in transgenic melatonin biosynthesis ovine HIOMT gene in switchgrass

    Directory of Open Access Journals (Sweden)

    Shan Yuan

    2016-11-01

    Full Text Available Melatonin serves pleiotropic functions in prompting plant growth and resistance to various stresses. The accurate biosynthetic pathway of melatonin remains elusive in plant species, while the N-acetyltransferase and O-methyltransferase were considered to be the last two key enzymes during its biosynthesis. To investigate the biosynthesis and metabolic pathway of melatonin in plants, the RNA-seq profile of overexpression of the ovine HIOMT was analyzed and compared with the previous transcriptome of transgenic oAANAT gene in switchgrass, a model plant for cellulosic ethanol production. A total of 946, 405 and 807 differentially expressed unigenes were observed in AANAT vs. control, HIOMT vs. control, and AANAT vs. HIOMT, respectively. The significantly upregulated (F-box/kelch-repeat protein, zinc finger BED domain-containing protein-3 genes were consistent with enhanced phenotypes of shoot, stem and root growth in transgenic oHIOMT switchgrass. Early flowering in overexpression of oHIOMT switchgrass involved in the regulation of flowering-time genes (APETALA2. Several stress resistant related genes (SPX domain-containing membrane protein, copper transporter 1, late blight resistance protein homolog R1A-6 OS etc. were specifically and significantly upregulated in transgenic oHIOMT only, while metabolism-related genes (phenylalanine-4-hydroxylase, tyrosine decarboxylase 1, protein disulfide-isomerase and galactinol synthase 2 etc. were significantly upregulated in transgenic oAANAT only. These results provide new sights into the biosynthetic and physiological functional networks of melatonin in plants.

  15. Comparative analyses of physiological responses of Cynodon dactylon accessions from Southwest China to sulfur dioxide toxicity.

    Science.gov (United States)

    Li, Xi; Wang, Ling; Li, Yiqiao; Sun, Lingxia; Cai, Shizhen; Huang, Zhuo

    2014-01-01

    Sulfur dioxide (SO2), a major air pollutant in developing countries, is highly toxic to plants. To achieve better air quality and landscape, planting appropriate grass species in severe SO2 polluted areas is very critical. Cynodon dactylon, a widely used warm season turfgrass species, has good SO2-tolerant ability. In this study, we selected 9 out of 38 C. dactylon accessions from Southwest China as representatives of high, intermediate SO2-tolerant and SO2-sensitive accessions to comparatively analyze their physiological differences in leaves under SO2 untreated and treated conditions. Our results revealed that SO2-tolerant C. dactylon accessions showed higher soluble sugar, proline, and chlorophyll a contents under both SO2 treated and untreated conditions; higher chlorophyll b and carotenoid under SO2 treated condition; lower reactive oxygen species (ROS) level, oxidative damages, and superoxide dismutase (SOD) activities under SO2 treated condition; and higher peroxidase (POD) activities under SO2 untreated condition. Further results indicated that SO2-tolerant C. dactylon accessions had higher sulfur contents under both SO2 treated and untreated conditions, consistent with higher SO activities under both SO2 treated and untreated conditions, and higher SiR activities under SO2 treated condition. Taken together, our results indicated that SO2 tolerance of C. dactylon might be largely related to soluble sugar, proline and chlorophyll a contents, and SO enzyme activity.

  16. Comparative analyses of longevity and senescence reveal variable survival benefits of living in zoos across mammals.

    Science.gov (United States)

    Tidière, Morgane; Gaillard, Jean-Michel; Berger, Vérane; Müller, Dennis W H; Bingaman Lackey, Laurie; Gimenez, Olivier; Clauss, Marcus; Lemaître, Jean-François

    2016-11-07

    While it is commonly believed that animals live longer in zoos than in the wild, this assumption has rarely been tested. We compared four survival metrics (longevity, baseline mortality, onset of senescence and rate of senescence) between both sexes of free-ranging and zoo populations of more than 50 mammal species. We found that mammals from zoo populations generally lived longer than their wild counterparts (84% of species). The effect was most notable in species with a faster pace of life (i.e. a short life span, high reproductive rate and high mortality in the wild) because zoos evidently offer protection against a number of relevant conditions like predation, intraspecific competition and diseases. Species with a slower pace of life (i.e. a long life span, low reproduction rate and low mortality in the wild) benefit less from captivity in terms of longevity; in such species, there is probably less potential for a reduction in mortality. These findings provide a first general explanation about the different magnitude of zoo environment benefits among mammalian species, and thereby highlight the effort that is needed to improve captive conditions for slow-living species that are particularly susceptible to extinction in the wild.

  17. Comparative and bioinformatics analyses of pathogenic bacterial secretomes identified by mass spectrometry in Burkholderia species.

    Science.gov (United States)

    Nguyen, Thao Thi; Chon, Tae-Soo; Kim, Jaehan; Seo, Young-Su; Heo, Muyoung

    2017-07-01

    Secreted proteins (secretomes) play crucial roles during bacterial pathogenesis in both plant and human hosts. The identification and characterization of secretomes in the two plant pathogens Burkholderia glumae BGR1 and B. gladioli BSR3, which cause diseases in rice such as seedling blight, panicle blight, and grain rot, are important steps to not only understand the disease-causing mechanisms but also find remedies for the diseases. Here, we identified two datasets of secretomes in B. glumae BGR1 and B. gladioli BSR3, which consist of 118 and 111 proteins, respectively, using mass spectrometry approach and literature curation. Next, we characterized the functional properties, potential secretion pathways and sequence information properties of secretomes of two plant pathogens in a comparative analysis by various computational approaches. The ratio of potential non-classically secreted proteins (NCSPs) to classically secreted proteins (CSPs) in B. glumae BGR1 was greater than that in B. gladioli BSR3. For CSPs, the putative hydrophobic regions (PHRs) which are essential for secretion process of CSPs were screened in detail at their N-terminal sequences using hidden Markov model (HMM)-based method. Total 31 pairs of homologous proteins in two bacterial secretomes were indicated based on the global alignment (identity ≥ 70%). Our results may facilitate the understanding of the species-specific features of secretomes in two plant pathogenic Burkholderia species.

  18. Mutations institutionnelles et recompositions des territoires urbains en Afrique : une analyse à travers la problématique de l’accès à l’eau

    Directory of Open Access Journals (Sweden)

    Catherine Baron

    2006-09-01

    Full Text Available L’accès à l’eau est une priorité des politiques urbaines conduites dans les pays en développement. Ces politiques ont oscillé entre la volonté de généraliser l’accès aux réseaux afin de contrôler l’espace urbain et une segmentation de l’offre afin de cibler différemment les diverses catégories de la population. Quel est alors l’impact, au niveau spatial, des choix opérés dans ce domaine dans les métropoles d’Afrique Sub-saharienne francophone ? Nous articulerons des approches ciblées sur la compréhension des stratégies d’acteurs aux logiques parfois opposées, avec des analyses spatiales permettant de décoder la complexité de la structuration des espaces urbains. Nous repérerons trois phases caractérisées par une articulation originale entre les modes de gouvernance de l’eau retenus et la structuration des espaces urbains. Dans un premier temps, on constate une dualisation de l’espace urbain renforcée par un accès segmenté aux services. Puis, dans un deuxième temps, nous montrerons comment les préconisations faites dans le cadre de la Décennie Internationale de l’Eau Potable et de l’Assainissement des années 1980 correspondaient à une volonté d’homogénéisation de l’espace urbain. Enfin, dans un troisième temps, nous évaluerons l’impact de modèles tels que le partenariat public-privé dans les processus de fragmentation urbaine qui caractérisent ces mégalopoles d’Afrique Sub-saharienne francophone à la période contemporaine.Access to water is one of the major challenges of urban policies implemented in developing countries. These policies aimed either to provide a global access in order to control urban spaces or to segment water supply to offer different services and features to comply with the diversity of actors. What is therefore the impact, in terms of spatial dimension, of different strategies followed by French speaking Sub-Saharan African cities ? In this paper, we

  19. Breast and cervical screening by race/ethnicity: comparative analyses before and during the Great Recession.

    Science.gov (United States)

    King, Christopher J; Chen, Jie; Garza, Mary A; Thomas, Stephen B

    2014-04-01

    Traditionally, economic recessions have resulted in decreased utilization of preventive health services. To explore racial and ethnic differences in breast and cervical cancer screening rates before and during the Great Recession. The Medical Expenditure Panel was the source for identifying 10,894 women, ages 50-74 for breast screening and 19,957 women, ages 21-65 for cervical screening. Survey years included 2004-2005 and 2009-2010. Dependent variables were as follows: 1) receipt of mammogram within the past 2 years; and 2) receipt of a Pap smear within the past 3 years. The interaction of the recession and the likelihood of screening between whites and minorities was analyzed. Multivariate regressions were applied to estimate the likelihood of screening for the two time periods while controlling for a recession variable. Nationally, breast and cervical cancer screening rates dropped during the recession period; white women contributed most to the decline. However, there were significant improvements in timely screening for both cancers among Hispanics during the recession period. After controlling for the recession, African American women were more likely to have timely screenings compared to white women. Screening rates during the recession were lowest in the South, Midwest and West. There was a national reduction in the percentages of women who obtained timely breast and cervical screenings during the Great Recession. Outreach efforts are needed to ensure that women who were not screened during the recession are screened. Widespread education about the Affordable Care Act may be helpful. Copyright © 2014 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  20. Comparative exergy analyses of Jatropha curcas oil extraction methods: Solvent and mechanical extraction processes

    International Nuclear Information System (INIS)

    Ofori-Boateng, Cynthia; Keat Teong, Lee; JitKang, Lim

    2012-01-01

    Highlights: ► Exergy analysis detects locations of resource degradation within a process. ► Solvent extraction is six times exergetically destructive than mechanical extraction. ► Mechanical extraction of jatropha oil is 95.93% exergetically efficient. ► Solvent extraction of jatropha oil is 79.35% exergetically efficient. ► Exergy analysis of oil extraction processes allow room for improvements. - Abstract: Vegetable oil extraction processes are found to be energy intensive. Thermodynamically, any energy intensive process is considered to degrade the most useful part of energy that is available to produce work. This study uses literature values to compare the efficiencies and degradation of the useful energy within Jatropha curcas oil during oil extraction taking into account solvent and mechanical extraction methods. According to this study, J. curcas seeds on processing into J. curcas oil is upgraded with mechanical extraction but degraded with solvent extraction processes. For mechanical extraction, the total internal exergy destroyed is 3006 MJ which is about six times less than that for solvent extraction (18,072 MJ) for 1 ton J. curcas oil produced. The pretreatment processes of the J. curcas seeds recorded a total internal exergy destructions of 5768 MJ accounting for 24% of the total internal exergy destroyed for solvent extraction processes and 66% for mechanical extraction. The exergetic efficiencies recorded are 79.35% and 95.93% for solvent and mechanical extraction processes of J. curcas oil respectively. Hence, mechanical oil extraction processes are exergetically efficient than solvent extraction processes. Possible improvement methods are also elaborated in this study.

  1. Comparative analyses of the bacterial microbiota of the human nostril and oropharynx.

    Science.gov (United States)

    Lemon, Katherine P; Klepac-Ceraj, Vanja; Schiffer, Hilary K; Brodie, Eoin L; Lynch, Susan V; Kolter, Roberto

    2010-06-22

    The nose and throat are important sites of pathogen colonization, yet the microbiota of both is relatively unexplored by culture-independent approaches. We examined the bacterial microbiota of the nostril and posterior wall of the oropharynx from seven healthy adults using two culture-independent methods, a 16S rRNA gene microarray (PhyloChip) and 16S rRNA gene clone libraries. While the bacterial microbiota of the oropharynx was richer than that of the nostril, the oropharyngeal microbiota varied less among participants than did nostril microbiota. A few phyla accounted for the majority of the bacteria detected at each site: Firmicutes and Actinobacteria in the nostril and Firmicutes, Proteobacteria, and Bacteroidetes in the oropharynx. Compared to culture-independent surveys of microbiota from other body sites, the microbiota of the nostril and oropharynx show distinct phylum-level distribution patterns, supporting niche-specific colonization at discrete anatomical sites. In the nostril, the distribution of Actinobacteria and Firmicutes was reminiscent of that of skin, though Proteobacteria were much less prevalent. The distribution of Firmicutes, Proteobacteria, and Bacteroidetes in the oropharynx was most similar to that in saliva, with more Proteobacteria than in the distal esophagus or mouth. While Firmicutes were prevalent at both sites, distinct families within this phylum dominated numerically in each. At both sites there was an inverse correlation between the prevalences of Firmicutes and another phylum: in the oropharynx, Firmicutes and Proteobacteria, and in the nostril, Firmicutes and Actinobacteria. In the nostril, this inverse correlation existed between the Firmicutes family Staphylococcaceae and Actinobacteria families, suggesting potential antagonism between these groups.

  2. The comparative analyses of different diagnostic approaches in detection of gastroesophageal reflux disease in children.

    Science.gov (United States)

    Ristic, Nina; Milovanovic, Ivan; Radusinovic, Milica; Stevic, Marija; Ristic, Milos; Ristic, Maja; Kisic Tepavcevic, Darija; Alempijevic, Tamara

    2017-01-01

    The aim of this study was to compare the different diagnostic approaches in detection of gastroesophageal reflux disease in children presented with symptoms suggesting gastroesophageal reflux disease. The study design was cross sectional. The study retrospectively included all children who underwent combined multiple intraluminal impedance and pH (pH-MII) monitoring due to gastrointestinal and/or extraesophageal symptoms suggesting gastroesophageal reflux disease at University Children's Hospital in Belgrade, from July 2012 to July 2016. A total of 218 (117 boys/101 girls), mean age 6.7 years (range 0.06-18.0 years), met the inclusion criteria. Gastroesophageal reflux disease was found in 128 of 218 children (57.4%) by pH-MII and in 76 (34.1%) children by pH metry alone. Using pH-MII monitoring as gold standard, sensitivity of pH-metry was lowest in infants (22.9%), with tendency to increase in older age groups (reaching 76.4% in children ≥ 9 years). The sensitivity of pH-metry alone in children with extraesophageal symptoms was 38.1%, while the sensitivity of pH-metry in children with gastrointestinal symptoms was 63.8%. Reflux esophagitis was identified in 31 (26.1%) of 119 children who underwent endoscopy. Logistic regression analysis showed that best predictors of endoscopic reflux esophagitis are the longest acid episode (OR = 1.52, preflux composite score (OR = 3.31, preflux composite score ≥ 29 (AUC 0.786, CI 0.695-0.877, preflux ≥ 18 minutes (AUC 0.784, CI 0.692-0.875, pgastroesophageal reflux disease, especially in infants. Our findings also showed that pH-MII parameters correlated significantly with the endoscopically confirmed erosive esophagitis.

  3. Comparative Genetic Analyses of Human Rhinovirus C (HRV-C) Complete Genome from Malaysia

    Science.gov (United States)

    Khaw, Yam Sim; Chan, Yoke Fun; Jafar, Faizatul Lela; Othman, Norlijah; Chee, Hui Yee

    2016-01-01

    Human rhinovirus-C (HRV-C) has been implicated in more severe illnesses than HRV-A and HRV-B, however, the limited number of HRV-C complete genomes (complete 5′ and 3′ non-coding region and open reading frame sequences) has hindered the in-depth genetic study of this virus. This study aimed to sequence seven complete HRV-C genomes from Malaysia and compare their genetic characteristics with the 18 published HRV-Cs. Seven Malaysian HRV-C complete genomes were obtained with newly redesigned primers. The seven genomes were classified as HRV-C6, C12, C22, C23, C26, C42, and pat16 based on the VP4/VP2 and VP1 pairwise distance threshold classification. Five of the seven Malaysian isolates, namely, 3430-MY-10/C22, 8713-MY-10/C23, 8097-MY-11/C26, 1570-MY-10/C42, and 7383-MY-10/pat16 are the first newly sequenced complete HRV-C genomes. All seven Malaysian isolates genomes displayed nucleotide similarity of 63–81% among themselves and 63–96% with other HRV-Cs. Malaysian HRV-Cs had similar putative immunogenic sites, putative receptor utilization and potential antiviral sites as other HRV-Cs. The genomic features of Malaysian isolates were similar to those of other HRV-Cs. Negative selections were frequently detected in HRV-Cs complete coding sequences indicating that these sequences were under functional constraint. The present study showed that HRV-Cs from Malaysia have diverse genetic sequences but share conserved genomic features with other HRV-Cs. This genetic information could provide further aid in the understanding of HRV-C infection. PMID:27199901

  4. Comparative Transcriptome and Microscopy Analyses Provide Insights into Flat Shape Formation in Peach (Prunus persica

    Directory of Open Access Journals (Sweden)

    Jian Guo

    2018-01-01

    Full Text Available Fruit shape is an important external characteristic that consumers use to select preferred fruit cultivars. In peach, the flat fruit cultivars have become more and more popular worldwide. Genetic markers closely linking to the flat fruit trait have been identified and are useful for marker-assisted breeding. However, the cellular and genetic mechanisms underpinning flat fruit formation are still poorly understood. In this study, we have revealed the differences in fruit cell number, cell size, and in gene expression pattern between the traditional round fruit and modern flat fruit cultivars. Flat peach cultivars possessed significantly lower number of cells in the vertical axis because cell division in the vertical direction stopped early in the flat fruit cultivars at 15 DAFB (day after full bloom than in round fruit cultivars at 35 DAFB. This resulted in the reduction in vertical development in the flat fruit. Significant linear relationship was observed between fruit vertical diameter and cell number in vertical axis for the four examined peach cultivars (R2 = 0.9964 at maturation stage, and was also observed between fruit vertical diameter and fruit weight (R2 = 0.9605, which indicated that cell number in vertical direction contributed to the flat shape formation. Furthermore, in RNA-seq analysis, 4165 differentially expressed genes (DEGs were detected by comparing RNA-seq data between flat and round peach cultivars at different fruit development stages. In contrast to previous studies, we discovered 28 candidate genes potentially responsible for the flat shape formation, including 19 located in the mapping site and 9 downstream genes. Our study indicates that flat and round fruit shape in peach is primarily determined by the regulation of cell production in the vertical direction during early fruit development.

  5. Lineage-specific evolution of the vertebrate Otopetrin gene family revealed by comparative genomic analyses

    Directory of Open Access Journals (Sweden)

    Ryan Joseph F

    2011-01-01

    Full Text Available Abstract Background Mutations in the Otopetrin 1 gene (Otop1 in mice and fish produce an unusual bilateral vestibular pathology that involves the absence of otoconia without hearing impairment. The encoded protein, Otop1, is the only functionally characterized member of the Otopetrin Domain Protein (ODP family; the extended sequence and structural preservation of ODP proteins in metazoans suggest a conserved functional role. Here, we use the tools of sequence- and cytogenetic-based comparative genomics to study the Otop1 and the Otop2-Otop3 genes and to establish their genomic context in 25 vertebrates. We extend our evolutionary study to include the gene mutated in Usher syndrome (USH subtype 1G (Ush1g, both because of the head-to-tail clustering of Ush1g with Otop2 and because Otop1 and Ush1g mutations result in inner ear phenotypes. Results We established that OTOP1 is the boundary gene of an inversion polymorphism on human chromosome 4p16 that originated in the common human-chimpanzee lineage more than 6 million years ago. Other lineage-specific evolutionary events included a three-fold expansion of the Otop genes in Xenopus tropicalis and of Ush1g in teleostei fish. The tight physical linkage between Otop2 and Ush1g is conserved in all vertebrates. To further understand the functional organization of the Ushg1-Otop2 locus, we deduced a putative map of binding sites for CCCTC-binding factor (CTCF, a mammalian insulator transcription factor, from genome-wide chromatin immunoprecipitation-sequencing (ChIP-seq data in mouse and human embryonic stem (ES cells combined with detection of CTCF-binding motifs. Conclusions The results presented here clarify the evolutionary history of the vertebrate Otop and Ush1g families, and establish a framework for studying the possible interaction(s of Ush1g and Otop in developmental pathways.

  6. Comparative analyses identified species-specific functional roles in oral microbial genomes

    Science.gov (United States)

    Chen, Tsute; Gajare, Prasad; Olsen, Ingar; Dewhirst, Floyd E.

    2017-01-01

    ABSTRACT The advent of next generation sequencing is producing more genomic sequences for various strains of many human oral microbial species and allows for insightful functional comparisons at both intra- and inter-species levels. This study performed in-silico functional comparisons for currently available genomic sequences of major species associated with periodontitis including Aggregatibacter actinomycetemcomitans (AA), Porphyromonas gingivalis (PG), Treponema denticola (TD), and Tannerella forsythia (TF), as well as several cariogenic and commensal streptococcal species. Complete or draft sequences were annotated with the RAST to infer structured functional subsystems for each genome. The subsystems profiles were clustered to groups of functions with similar patterns. Functional enrichment and depletion were evaluated based on hypergeometric distribution to identify subsystems that are unique or missing between two groups of genomes. Unique or missing metabolic pathways and biological functions were identified in different species. For example, components involved in flagellar motility were found only in the motile species TD, as expected, with few exceptions scattered in several streptococcal species, likely associated with chemotaxis. Transposable elements were only found in the two Bacteroidales species PG and TF, and half of the AA genomes. Genes involved in CRISPR were prevalent in most oral species. Furthermore, prophage related subsystems were also commonly found in most species except for PG and Streptococcus mutans, in which very few genomes contain prophage components. Comparisons between pathogenic (P) and nonpathogenic (NP) genomes also identified genes potentially important for virulence. Two such comparisons were performed between AA (P) and several A. aphrophilus (NP) strains, and between S. mutans + S. sobrinus (P) and other oral streptococcal species (NP). This comparative genomics approach can be readily used to identify functions unique to

  7. Comparative analyses of olfactory systems in terrestrial crabs (Brachyura: evidence for aerial olfaction?

    Directory of Open Access Journals (Sweden)

    Jakob Krieger

    2015-12-01

    Full Text Available Adaptations to a terrestrial lifestyle occurred convergently multiple times during the evolution of the arthropods. This holds also true for the “true crabs” (Brachyura, a taxon that includes several lineages that invaded land independently. During an evolutionary transition from sea to land, animals have to develop a variety of physiological and anatomical adaptations to a terrestrial life style related to respiration, reproduction, development, circulation, ion and water balance. In addition, sensory systems that function in air instead of in water are essential for an animal’s life on land. Besides vision and mechanosensory systems, on land, the chemical senses have to be modified substantially in comparison to their function in water. Among arthropods, insects are the most successful ones to evolve aerial olfaction. Various aspects of terrestrial adaptation have also been analyzed in those crustacean lineages that evolved terrestrial representatives including the taxa Anomala, Brachyura, Amphipoda, and Isopoda. We are interested in how the chemical senses of terrestrial crustaceans are modified to function in air. Therefore, in this study, we analyzed the brains and more specifically the structure of the olfactory system of representatives of brachyuran crabs that display different degrees of terrestriality, from exclusively marine to mainly terrestrial. The methods we used included immunohistochemistry, detection of autofluorescence- and confocal microscopy, as well as three-dimensional reconstruction and morphometry. Our comparative approach shows that both the peripheral and central olfactory pathways are reduced in terrestrial members in comparison to their marine relatives, suggesting a limited function of their olfactory system on land. We conclude that for arthropod lineages that invaded land, evolving aerial olfaction is no trivial task.

  8. Computed tomography of the patellofemoral alignment after arthroscopic reconstruction following patella dislocation; Postoperative Bestimmung des patellofemoralen Alignements nach Patellaluxation - eine computertomographische Analyse

    Energy Technology Data Exchange (ETDEWEB)

    Schroeder, R.J.; Hidajat, N.; Maeurer, J.; Felix, R. [Klinik fuer Strahlenheilkunde, Charite, Campus Virchow-Klinikum, Humboldt-Univ. Berlin (Germany); Weiler, A.; Hoeher, J. [Sektion Sporttraumatologie und Arthroskopie, Klinik fuer Unfall- und Wiederherstellungschirurgie, Charite, Campus Virchow-Klinikum, Humboldt-Univ. Berlin (Germany)

    2003-04-01

    Purpose: To evaluate the diagnostic impact of different CT-based measurements to analyze the patellofemoral alignment after arthroscopic reconstruction in patients with patella dislocation. Materials and Methods: In 18 patients with dislocation of the patella, CT of the patellofemoral joint was performed after arthroscopic reconstruction. Various methods recommended in the literature were used to analyze the structure and the alignment of the patellofemoral joint with a relaxed quadriceps muscle. Axial CT scans were taken in four different knee flexion angles (15 , 30 , 45 , 60 ). Results: After arthroscopic stabilization in patients with patella dislocation, only the lateral patellofemoral angle (15 and 30 knee flexion) and the congruence angle (15 knee flexion) showed significant differences between the CT-measurements in the normal and the operated group. The differences of the remaining mean values were not significant due to a high standard deviation. With increasing flexion of the knee, the differences between the normal and the dislocation group almost disappeared. Only the lateral patellofemoral angle, the patella tilt and the lateral patella shift revealed differences between the normal and the group with recurrent dislocation in every degree of knee flexion. With increasing knee flexion above 30 and especially at 60 , the majority of the measured values returned to the normal range. Conclusions: For CT-measurements of the patellofemoral joint after arthroscopic stabilization, the patellofemoral angle and the congruence angle seemed to be most useful. The measurements of the patellofemoral joint should be taken in various degrees of knee flexion. (orig.) [German] Ziel: Evaluation der Aussagekraft verschiedener CT-Vermessungsmethoden des Patellofemoralgelenkes nach arthroskopischer Stabilisierung bei Patellaluxation. Material und Methode: Axiale CT-Vermessung des Patellofemoralgelenkes bei 18 Patienten nach arthroskopischer medialer patellofemoraler Naht

  9. La dimension sociale dans un master post-universitaire à distance : outils, animation et analyse des interactions The social dimension within an online post-graduate course: tools, simulation and interaction analysis

    Directory of Open Access Journals (Sweden)

    Simone Torsani

    2008-11-01

    Full Text Available Les technologies de l'information et de la communication (TIC dans la formation peuvent favoriser l'adoption de modèles éducatifs de type socioconstructiviste. Dans ces contextes de formation (computer-supported collaborative learning, CSCL, une attention particulière est consacrée à la création de la communauté d'apprentissage et aux relations qui s'instaurent entre ses membres. Le master de haute formation en traduction juridique de l'université de Gênes – projet F@rum (Poli et al., 2004, se base sur ces théories. Pour favoriser au maximum le développement de la présence sociale de la communauté d'apprentissage, un "jeu de simulation socio-professionnel" (Debyser, 1996 ; Rossi, 2002 a été organisé par l'équipe du master, à l'intérieur d'une plateforme dédiée. Dans cette étude, nous décrirons les initiatives destinées à encourager la présence sociale à l'intérieur du master. Nous chercherons à comprendre également si et dans quelle mesure ces initiatives ont influencé la présence sociale des participants ; si elles ont stimulé la création de la communauté d'apprentissage et si elles ont contribué à l'atteinte des objectifs cognitifs du master. Cette contribution se fonde en particulier sur les résultats de l'analyse des interactions des apprenants indiquant la présence sociale (Garrison et al., 1999. L'analyse des messages des forums repose sur un modèle d'évaluation dit "mixte" (quantitatif et qualitatif à cinq dimensions (Pozzi et al., 2007 inspiré des "communities of inquiry" (Garrison & Anderson, 2003.The use of ICTs in the field of education can promote the adoption of "social constructivist" approaches to learning. In these contexts of education (computer-supported collaborative learning, CSCL, a particular attention is paid to the creation of the "learning community" and to the relationships the members of the community establish among them. The post-graduate course in legal translation of

  10. From the coupling between ion beam analysis techniques and physico-chemical characterization methods to the study of irradiation effects on materials behaviour; Du couplage des techniques d'analyse par faisceaux d'ions et des methodes de caracterisation physico-chimique a l'etude des effets d'irradiation sur le comportement des materiaux

    Energy Technology Data Exchange (ETDEWEB)

    Millard-Pinard, N

    2003-07-01

    The general purpose of my research work is to follow and to interpret the surface evolution of materials, which have received several treatments. During my PhD and my post-doc work, my field of research was tribology. Since I arrived in the 'Aval du Cycle Electronucleaire' group of the Institut de Physique Nucleaire de Lyon, my research activities are in line with the CNRS program 'PACE ' (Programme sur l'Aval du Cycle Electronucleaire) within the ACTINET network. They are coordinated by the PARIS (Physico-chimie des actinides et autres radioelements en solution et aux interfaces) and NOMADE (NOuveaux MAteriaux pour les DEchets) GDR with ANDRA (Agence Nationale pour la gestion des Dechets RAdioactifs), EDF and IRSN (Institut de Radioprotection et de Surete Nucleaire) as partner organisations. My work focused on the study of fission products and actinides migration in barrier materials, which may be capable of assuring the long term safety of deep geological repositories. Until now, it was necessary to use the coupling of ion beam analysis techniques and physico-chemical characterization techniques. During the last few months, I have became interested in understanding radiolytic effects. This new orientation has led us to use ion beams as an irradiating tool. These irradiation experiments are pursued in three major projects. The study of cobalt sulfide inhibition effects of radiolysis gas production during the irradiation of model organic molecules. This is a collaboration with the IRSN, the Institut de Recherche sur la Catalyse and the Ecole Nationale Superieure des Mines de Saint-Etienne. A PhD, co-directed by M. Pijolat from ENSMSE and myself, concerning this study will start in October 2003. Water radiolysis effects on iron corrosion are also studied in the particular case of vitrified nuclear waste containers, which will be stored in deep geological repositories. One ANDRA financed PhD, co-directed by Nathalie Moncoffre and myself, is dedicated to this study

  11. From the coupling between ion beam analysis techniques and physico-chemical characterization methods to the study of irradiation effects on materials behaviour; Du couplage des techniques d'analyse par faisceaux d'ions et des methodes de caracterisation physico-chimique a l'etude des effets d'irradiation sur le comportement des materiaux

    Energy Technology Data Exchange (ETDEWEB)

    Millard-Pinard, N

    2003-07-01

    The general purpose of my research work is to follow and to interpret the surface evolution of materials, which have received several treatments. During my PhD and my post-doc work, my field of research was tribology. Since I arrived in the 'Aval du Cycle Electronucleaire' group of the Institut de Physique Nucleaire de Lyon, my research activities are in line with the CNRS program 'PACE ' (Programme sur l'Aval du Cycle Electronucleaire) within the ACTINET network. They are coordinated by the PARIS (Physico-chimie des actinides et autres radioelements en solution et aux interfaces) and NOMADE (NOuveaux MAteriaux pour les DEchets) GDR with ANDRA (Agence Nationale pour la gestion des Dechets RAdioactifs), EDF and IRSN (Institut de Radioprotection et de Surete Nucleaire) as partner organisations. My work focused on the study of fission products and actinides migration in barrier materials, which may be capable of assuring the long term safety of deep geological repositories. Until now, it was necessary to use the coupling of ion beam analysis techniques and physico-chemical characterization techniques. During the last few months, I have became interested in understanding radiolytic effects. This new orientation has led us to use ion beams as an irradiating tool. These irradiation experiments are pursued in three major projects. The study of cobalt sulfide inhibition effects of radiolysis gas production during the irradiation of model organic molecules. This is a collaboration with the IRSN, the Institut de Recherche sur la Catalyse and the Ecole Nationale Superieure des Mines de Saint-Etienne. A PhD, co-directed by M. Pijolat from ENSMSE and myself, concerning this study will start in October 2003. Water radiolysis effects on iron corrosion are also studied in the particular case of vitrified nuclear waste containers, which will be stored in deep geological repositories. One ANDRA financed PhD, co-directed by Nathalie Moncoffre and myself, is

  12. Comparative analyses reveal discrepancies among results of commonly used methods for Anopheles gambiaemolecular form identification

    Directory of Open Access Journals (Sweden)

    Pinto João

    2011-08-01

    Full Text Available Abstract Background Anopheles gambiae M and S molecular forms, the major malaria vectors in the Afro-tropical region, are ongoing a process of ecological diversification and adaptive lineage splitting, which is affecting malaria transmission and vector control strategies in West Africa. These two incipient species are defined on the basis of single nucleotide differences in the IGS and ITS regions of multicopy rDNA located on the X-chromosome. A number of PCR and PCR-RFLP approaches based on form-specific SNPs in the IGS region are used for M and S identification. Moreover, a PCR-method to detect the M-specific insertion of a short interspersed transposable element (SINE200 has recently been introduced as an alternative identification approach. However, a large-scale comparative analysis of four widely used PCR or PCR-RFLP genotyping methods for M and S identification was never carried out to evaluate whether they could be used interchangeably, as commonly assumed. Results The genotyping of more than 400 A. gambiae specimens from nine African countries, and the sequencing of the IGS-amplicon of 115 of them, highlighted discrepancies among results obtained by the different approaches due to different kinds of biases, which may result in an overestimation of MS putative hybrids, as follows: i incorrect match of M and S specific primers used in the allele specific-PCR approach; ii presence of polymorphisms in the recognition sequence of restriction enzymes used in the PCR-RFLP approaches; iii incomplete cleavage during the restriction reactions; iv presence of different copy numbers of M and S-specific IGS-arrays in single individuals in areas of secondary contact between the two forms. Conclusions The results reveal that the PCR and PCR-RFLP approaches most commonly utilized to identify A. gambiae M and S forms are not fully interchangeable as usually assumed, and highlight limits of the actual definition of the two molecular forms, which might

  13. Model-based analyses to compare health and economic outcomes of cancer control: inclusion of disparities.

    Science.gov (United States)

    Goldie, Sue J; Daniels, Norman

    2011-09-21

    Disease simulation models of the health and economic consequences of different prevention and treatment strategies can guide policy decisions about cancer control. However, models that also consider health disparities can identify strategies that improve both population health and its equitable distribution. We devised a typology of cancer disparities that considers types of inequalities among black, white, and Hispanic populations across different cancers and characteristics important for near-term policy discussions. We illustrated the typology in the specific example of cervical cancer using an existing disease simulation model calibrated to clinical, epidemiological, and cost data for the United States. We calculated average reduction in cancer incidence overall and for black, white, and Hispanic women under five different prevention strategies (Strategies A1, A2, A3, B, and C) and estimated average costs and life expectancy per woman, and the cost-effectiveness ratio for each strategy. Strategies that may provide greater aggregate health benefit than existing options may also exacerbate disparities. Combining human papillomavirus vaccination (Strategy A2) with current cervical cancer screening patterns (Strategy A1) resulted in an average reduction of 69% in cancer incidence overall but a 71.6% reduction for white women, 68.3% for black women, and 63.9% for Hispanic women. Other strategies targeting risk-based screening to racial and ethnic minorities reduced disparities among racial subgroups and resulted in more equitable distribution of benefits among subgroups (reduction in cervical cancer incidence, white vs. Hispanic women, 69.7% vs. 70.1%). Strategies that employ targeted risk-based screening and new screening algorithms, with or without vaccination (Strategies B and C), provide excellent value. The most effective strategy (Strategy C) had a cost-effectiveness ratio of $28,200 per year of life saved when compared with the same strategy without

  14. Photonique des Morphos

    CERN Document Server

    Berthier, Serge

    2010-01-01

    La photonique est déjà présente dans notre vie quotidienne, et on attend maintenant que la manipulation des photons permette aussi le traitement logique des informations. Cependant, l’élément de base qui permet cette manipulation de la lumière, le cristal photonique, est d’une réalisation complexe et mal contrôlée. Dans la course à la maîtrise de la lumière, les structures photoniques naturelles ont beaucoup à nous apprendre. C’est ce que nous montre Serge Berthier qui étudie dans ce livre la structure des écailles des Morphos. Tenant compte de l’essor récent des approches biomimétiques, il présente de manière détaillée plus de dix-huit techniques expérimentales utilisées pour ses analyses, ainsi que les diverses approches théoriques développées pour la modélisation de structures multi-échelles complexes. Première étude quasi-exhaustive des structures fines d’un genre et des propriétés optiques ainsi que colorimétriques générées, ce livre fournit aux entomologiste...

  15. Etude du strabisme chez des enfants de 0 à 15 ans suivis a Lubumbashi, République Démocratique du Congo: analyse des aspects épidémiologiques et cliniques

    Science.gov (United States)

    Bienvenu, Yogolelo Asani; Angel, Musau Nkola; Sebastien, Mbuyi Musanzayi; Philippe, Cilundika Mulenga; Léon, Kabamba Ngombe; Eugene, Twite Kabange; Chami, Cham Lubamba; Prosper, Kalenga Muenze Kayamba; Claude, Speeg-Schatz; Gaby, Chenge Borasisi

    2015-01-01

    Introduction Le strabisme est défini comme un syndrome à double composante: motrice et sensorielle. Le but de ce travail est de décrire les aspects épidémiologiques et cliniques du strabisme chez l'enfant congolais de 0 à 15 ans dans la ville de Lubumbashi. Méthodes Il s'agit d'une étude descriptive longitudinale sur les aspects épidémiologiques et cliniques du strabisme chez l'enfant congolais de 0 à 15 ans dans la ville de Lubumbashi entre Décembre 2012 à Décembre 2013. Nous avons recueilli l’âge des patients, leur sexe, leur provenance, le type de strabisme, la réfraction, le fond d'oeil, les antécédents (hérédité) ainsi que le type de la déviation strabique observé sur 70 patients. Résultats Nous avons observé 70 cas de strabisme manifeste dont 31 cas (44,28%) étaient dans la tranche d’âge comprise entre 0 et 5 ans. L’âge moyen de nos patients était de 6,7 ans avec une prédominance du sexe féminin, soit 51,42%. Le strabisme était convergent dans 65,71%, divergent dans 30%, et vertical dans 4,28%. Les ésotropies représentaient 65 cas (92,85%), quatre cas (5,71%) avaient un antécédent familial de strabisme au premier degré de parenté, 21 cas (30%) au second degré de parenté, 45 cas (64,28%) n'avaient pas cet antécédent. L'oeil gauche était le plus dominé dans 30% des cas. Les facteurs favorisant le strabisme étaient inconnus dans 54 cas (77,14%). Le strabisme était secondaire à l'hypermétropie chez 32 patients (42,71%). Conclusion La fréquence du strabisme dans la ville de Lubumbashi chez les enfants âgés de 0 à 15 ans est de 0,50%. Comme dans la plupart des études sur le strabisme de l'enfant, c'est l’ésotropie qui est la déviation la plus commune. PMID:26834919

  16. Etude comparative du contenu en récepteurs de la 1,25-dihydroxyvitamine D3 dans des muqueuses et des adénocarcinomes digestifs

    NARCIS (Netherlands)

    Meggouh, F.; Lointier, P.; Pezet, D.; Saez, S.

    1990-01-01

    We have studied and compared the 1,25-dihydroxyvitamin D3 receptor (RD3) content of 154 human digestive carcinoma with the normal mucosa one, removed at distance from the same surgical specimen. The distribution of biopsies is as follows: 5 oesophagus, 10 stomach, 6 small bowel, 35 right colon, 47

  17. Comparative energy consumption analyses of an ultra high frequency induction heating system for material processing applications

    Directory of Open Access Journals (Sweden)

    Taştan, Mehmet

    2015-09-01

    Full Text Available This study compares an energy consumption results of the TI-6Al-4V based material processing under the 900 kHz induction heating for different cases. By this means, total power consumption and energy consumptions per sample and amount have been analyzed. Experiments have been conducted with 900 kHz, 2.8 kW ultra-high frequency induction system. Two cases are considered in the study. In the first case, TI-6Al-4V samples have been heated up to 900 °C with classical heating method, which is used in industrial applications, and then they have been cooled down by water. Afterwards, the samples have been heated up to 600 °C, 650 °C and 700 °C respectively and stress relieving process has been applied through natural cooling. During these processes, energy consumptions for each defined process have been measured. In the second case, unlike the first study, can be used five different samples have been heated up to the various temperatures between 600 °C and 1120 °C and energy consumptions have been measured for these processes. Thereby, the effect of temperature increase on each sample on energy cost has been analyzed. It has been seen that as a result of heating the titanium bulk materials, which have been used in the experiment, with ultra high frequency induction, temperature increase also increases the energy consumption. But it has been revealed that the increase rate in the energy consumption is more than the increase rate of the temperature.En este estudio se comparan los consumos energéticos al procesar Ti-6Al-4V por inducción a 900 kHz. Se ha analizado la potencia total consumida y la energía consumida por muestra. Los experimentos se han realizado en un sistema de inducción de ultra alta frecuencia a 900 kHz, 2,8 kW. Se han considerado dos casos, en el primero se ha calentado Ti-6Al-4V a 900 °C por el método clásico usado en la industria y enfriado en agua; posteriormente las muestras se han calentado a 600, 650 y 700 °C y

  18. Analyze of phase's mechanical behaviour of a multiphase polycrystalline alloy by X-ray and neutron diffraction; Analyse du comportement mecanique des constituants d'un alliage polycristallin multiphase par diffraction des rayons X et neutronique

    Energy Technology Data Exchange (ETDEWEB)

    Dakhlaoui, R

    2006-12-15

    The aim of this work is to propose a methodology using diffraction methods and theoretical approaches of self-consistent modeling in order to analyze and better understand the mechanical behavior of each phase of hot-rolled duplex stainless steel. The purpose of the experimental study is to characterize the local mechanical behavior of phases under uniaxial loading. X-ray and neutron diffraction which enable to measure strains in each phase separately were used in this aim. Austenitic and ferritic phase stresses are determined by X-ray diffraction during tensile tests. Evolution of the elastic strains in each phase was measured by neutron diffraction using 'time-of-flight' method during tensile and compression tests. Elastic constants were given using the self-consistent model for a purely elastic deformation. To reproduce the mechanical behaviour of the studied material, self-consistent polycrystalline micro-mechanical model for elastoplastic deformation has been adapted and confronted to experimental results. Crystallographic texture and initial residual stresses were considered in this analysis. Critical shear stresses and hardening parameters of each phase of the studied duplex steel have been identified. Results of this study showed that the austenitic phase represents the softest and the most hardenable phase. Taking into account in calculations the initial residual stresses in the non deformed sample leads to the conclusion that the initial stresses modify considerably the values of phase's yield stresses. Good agreement has been noted comparing results obtained by XRD to those obtained by neutron diffraction. The problem of relaxation of normal stresses in the analysed layer by X-rays was analysed and discussed. Using XRD and self-consistent modelling, the effect of the chemical composition of the duplex stainless steel and the influence of ageing at 400 C degrees for 1000 h on the mechanical behaviour of austenitic and ferritic phases have

  19. Continuous analytical control of the streaming waters in a uranium treatment plant and of various chemical products using automatic discharge valves; Controle par analyse en continu des eaux de ruissellement d'une usine traitant de l'uranium et divers produits chimiques avec commande automatique des vannes de decharge

    Energy Technology Data Exchange (ETDEWEB)

    Archimbaud, M; Simeon, C [Commissariat a l' Energie Atomique, Pierrelatte (France)

    1968-07-01

    This report describes a method for controlling the streaming waters produced by the Pierrelatte Centre; it is based on continuous analysis, with simultaneous recording of the species liable to be found accidentally in the corresponding hydrological circuits (chlorides, fluorides, chromium VI, uranium). An alarm set off at pre-determined thresholds leads to an automatic cutting off of the discharge valves; the outward flow of the waters is thus interrupted. This study has shown the various applications which can be found for this water control method, and gives an idea of the cost price. (authors) [French] Ce rapport decrit un mode de controle des eaux de ruissellement provenant du Centre de Pierrelatte base sur une analyse en continu, avec enregistrement des corps susceptibles de se retrouver accidentellement dans les reseaux hydrologiques correspondants (chlorures, fluorures, chrome VI, uranium). Le declenchement d'une alarme a partir de seuils choisis permet de fermer automatiquement les vannes de decharge et d'arreter ainsi l'ecoulement vers l'exterieur. Cette etude montre quelles peuvent etre les diverses applications de cette methode de controle des eaux et elle indique un ordre de grandeur du prix de revient. (auteurs)

  20. Usages des TIC et socialisation professionnelle des enseignants-chercheurs

    OpenAIRE

    Lavielle-Gutnik, Nathalie; Massou, Luc

    2013-01-01

    En prenant appui sur une nouvelle analyse des données recueillies dans l’enquête Tec-Meus (2008-2011, MSH Lorraine) sur la place accordée par des enseignants-chercheurs en sciences humaines et sociales aux technologies de l’information et de la communication (TIC) dans leur activité d’enseignement, nous souhaitons nous focaliser dans cet article sur la compréhension des processus de socialisation professionnelle en jeu dans leur usage déclaré des TIC. Par socialisation professionnelle, nous e...

  1. Contesting Citizenship: Comparative Analyses

    DEFF Research Database (Denmark)

    Siim, Birte; Squires, Judith

    2007-01-01

    The pursuit of equal citizenship has been complicated by two recent developments: the emergence of multi-level governance (and with it the growing importance of local, regional and global levels of citizenship practices) and the emrgence of group recognition claims (which signals the growing impo...

  2. Contribution des éléments de transition à la compréhension de la génèse des basaltes océaniques. Analyse des éléments traces dans les roches par spectrométrie de fluorescence X

    OpenAIRE

    Bougault, Henri

    1980-01-01

    En insistant sur les limites de la définition d'un élément trace et sur les hypothèses nécessaires à l'élaboration des modèles classiques de fusion partielle et de cristallisation fractionnée, le premier chapitre sert d'introduction générale. Le deuxième chapitre traite des propriétés des éléments de transition vis à vis des partages minéraux - liquides silicatés. Les chapitres III, éléments à forts coefficients de partage, et IV, éléments à faibles coefficients de partage, sont consacr...

  3. Analysis of the action of X-rays on the multiplication of a unicellular chlorophyllous organism: the chlorophycee scenesdesmus crassus chod (1961); Analyse de l'action des rayons X sur la multiplication d'un organisme chlorophyllien unicellulaire: la chlorophycee scenesdesmus crassus chod (1961)

    Energy Technology Data Exchange (ETDEWEB)

    Gilet, R; Ozenda, P [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1961-07-01

    The technique of growing cultures on agar-agar has made it possible to obtain on single cultures results which had previously been acquired on populations of unicellular algae in a liquid medium. (authors) [French] La technique de culture sur gelose a permis une analyse a l'echelle individuelle des resultats precedemment acquis sur des populations d'algues unicellulaires en milieu liquide. (auteurs)

  4. Comparative Study of the Methods Used for the Computer Resolution of Composite Gamma-Ray Spectra; Etude Comparative des Methodes Utilisees pour la Resolution de Spectres Gamma Complexes au Moyen d'un Ordinateur; Sravnitel'noe izuchenie metodov razresheniya sostavnykh gamma-spektrov pri pomoshchi schetno-reshayushchego ustrojstva; Estudio Comparativo de los Metodos Aplicados para Resolver Espectros Gamma Complejos Mediante Calculadoras

    Energy Technology Data Exchange (ETDEWEB)

    DeHaan, A. Jr.; Leventhal, L.; Benson, P. [Tracerlab, Richmond, CA (United States)

    1965-10-15

    analysis. Statistical estimates for the errors in the resulting concentration of the radionuclides are provided for each analytical method when they are applied to multicomponent radionuclide mixtures. (author) [French] La resolution du rayonnement de melanges oomplexes d'emetteurs gamma a ete facilitee par l'emploi de spectrometres gamma tres perfectionnes et de calculatrices numeriques. Ces appareils sont maintenant a la disposition de presque tousles laboratoires techniques. Les auteurs etudient les techniques utilisees dans leur laboratoire pour mesurer les concentrations individuelles de differents radionucleides emetteurs gamma dans des echantillons provenant de retombees radioactives et comparent les resultats obtenus par les differentes methodes mathematiques avec des echantillons de composition complexe. Les donnees fournies par l'ordinateur sont comparees avec les resultats obtenus par analyse radiochimique de l'echantillon. Apres avoir analyse des composes binaires au moyen des methodes decrites ci-apres, les auteurs ont etendu l'analyse aux emetteurs composes de nombreux elements. Ils ont mis au point une methode avec ordinateur qui normalise les spectres gamma de maniere a reduire au minimum le glissement a long terme du spectrometre et qui convertit le spectre en une configuration dont l'energie est l'une des coordonnees. Ils etudient par les diverses methodes ci-apres les effets d'un 'pic photoelectrique imprevu ', d'un element d'intensitezero et de la superposition de pics, en particulier dans le cas d'echantillons de faible activite. Les auteurs ont analyse les methodes mathematiques les plus courantes pour la resolution des diverses composantes d'un spectre gamma complexe. La plupart de ces methodes aboutissent a une evaluation des concentrations de differents emetteurs gamma par l'un des procedes suivants: 1. Elimination successive des radionucleides a pic photoelectrique de forte energie, le spectre pur etant extrait du spectre compose jusqu

  5. Perceptions locales de la manifestation des changements ...

    African Journals Online (AJOL)

    SARAH

    . PRPR. ERMA. DC. UD cluster 1 cluster 2. Pauvres. Riches et moyens. Figure 4. Positionnement des classes d'impacts socio-économiques des changements climatiques dans un système d'axes de l'analyse factorielle des ...

  6. La Moyenne Vallée de l’Euphrate syrien : étude préliminaire pour la cartographie des états de surface et des systèmes de drainage en vue d’une analyse paléoenvironnementale

    Directory of Open Access Journals (Sweden)

    Ch. Chataigner

    2000-05-01

    Full Text Available La moyenne vallée de l’Euphrate syrien constitue l’une des zones clé pour la diffusion du néolithique. Mais elle est aussi une zone d’intense mise en valeur sous forme d’aménagements hydrauliques. La télédétection peut jouer un rôle important comme image récente d’un paysage à disparaître, et comme document palliatif à la carence de certaines données pour une analyse paléoenvironnementale.

  7. Comparative study of the formation of fenchenes and of their N.M.R. spectra; Etude comparative de la formation des fenchenes et de leurs spectres de R.M.N

    Energy Technology Data Exchange (ETDEWEB)

    Coulombeau, A. [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1970-01-01

    The dehydration of {alpha}-fenchyl alcohol and {alpha}-iso-fenchyl alcohol is studied in detail: two new techniques (chromatography on silica with silver nitrate, and nuclear magnetic resonance) permit to analyse the formation of various fenchenes and to achieve the synthesis of {alpha}- and {beta}-fenchenes. (author) [French] On etudie en detail la deshydratation de l'{alpha}-fenchol et de l'{alpha}-isofenchol: grace a l'utilisation de deux techniques nouvelles (chromatographie sur silice impregnee de nitrate d'argent et resonance magnetique nucleaire), on a pu analyser la formation des divers fenchenes. On met au point la preparation de l'{alpha}- et du {beta}-fenchenes. (auteur)

  8. Comparative study of the formation of fenchenes and of their N.M.R. spectra; Etude comparative de la formation des fenchenes et de leurs spectres de R.M.N

    Energy Technology Data Exchange (ETDEWEB)

    Coulombeau, A [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1970-01-01

    The dehydration of {alpha}-fenchyl alcohol and {alpha}-iso-fenchyl alcohol is studied in detail: two new techniques (chromatography on silica with silver nitrate, and nuclear magnetic resonance) permit to analyse the formation of various fenchenes and to achieve the synthesis of {alpha}- and {beta}-fenchenes. (author) [French] On etudie en detail la deshydratation de l'{alpha}-fenchol et de l'{alpha}-isofenchol: grace a l'utilisation de deux techniques nouvelles (chromatographie sur silice impregnee de nitrate d'argent et resonance magnetique nucleaire), on a pu analyser la formation des divers fenchenes. On met au point la preparation de l'{alpha}- et du {beta}-fenchenes. (auteur)

  9. Comparative performance of fluorescent iron-core ballasts and electronic ballasts. Rendement comparatif des ballasts a noyau de fer et des ballasts electroniques pour eclairage fluorescent

    Energy Technology Data Exchange (ETDEWEB)

    Pasini, I

    1987-01-01

    Commercially available one- and two-lamp fluorescent luminaires were tested, and a number of electrical parameters were measured using varying combinations of lamps and either iron-core or electronic ballasts. Comprehensive photometric tests and thermal measurements were also conducted. The test results were tabulated and compared. The performance of the iron-core ballasts was found to be sufficiently close to nominally rated values to not raise concerns. Results from testing the electronic ballasts showed that the user has to be careful when selecting these ballasts, as they far exceed standard specification limits for current and voltage crest factors. All other electrical, photometric and thermal parameters are within accepted levels. An economic analysis was undertaken to determine cost benefits and payback periods for using electronic ballasts, the use of which will result in higher efficiency and lower power consumption. A project life of 20 years was assumed, and analysis was run for a power cost of $0.04/kWh. A unit made by Fyrnetics showed the lowest total annual owning and operating costs and had a payback period of 12.1 years. 13 figs., 13 tabs.

  10. Aussteigen aus dem Rechtsextremismus: Foto-Praxis, bildwissenschaftliche Analyse und Ausstellungsarbeit als Methoden individueller Reflexion und des wissenschaftlichen und (sozialpädagogischen Kompetenzerwerbs

    Directory of Open Access Journals (Sweden)

    Ulrike Pilarczyk

    2013-06-01

    Full Text Available Der Beitrag zeigt die medienpädagogischen und bildwissenschaftlichen Dimensionen eines zeitlich und thematisch gestaffelten Projektes auf. Ausgangspunkt war das in den Jahren 2009/10 von der Organisation EXIT-Deutschland in Berlin mit Aussteigern/-innen aus der rechtsextremen Szene initiierte Fotoprojekt «Lebensbilder». Die im Rahmen biografisch orientierter, medien- und sozialpädagogischer Fallarbeit entstandenen Fotos wurden als Prozess individueller Bilderzeugung und als Mittel zur Reflexion der jeweiligen Lebenssituation der Aussteiger(innen verstanden und eingesetzt. Eine Ausstellung schloss diese erste Phase des hier beschriebenen Projektes ab. Dem Wunsch folgend, die praktischen Erfahrungen aus der Arbeit mit Fotos wissenschaftlich überprüfen zu lassen, wurden in den Jahren 2011 und 2012 mit Studierenden am erziehungswissenschaftlichen Institut der TU Braunschweig die «Lebensbilder» zunächst einer wissenschaftlichen Bildanalyse unterzogen und anschliessend in einem gestalterisch-interpretativen Projekt durch die Studierenden zu einer Ausstellung weiterentwickelt.

  11. Brand(ed) content ou la stratégie du contenu : cadrage pour l’analyse des nouveaux dispositifs publicitaires

    OpenAIRE

    Guellec, Laurence

    2015-01-01

    Le brand(ed) content désigne des opérations publicitaires visant à construire un contenu de marque plutôt qu’à mettre en vedette un produit, dans lesquelles la vidéo en ligne est l’élément clef du dispositif, permettant d’associer de façon interactive les consommateurs à la démarche de promotion. Si le franglicisme « brand content » s’est imposé dans le domaine français, les dénominations de « branded content » ou de « brand entertainment » ont essaimé dans la langue internationale de la publ...

  12. Comparative study of {beta} decays and of the model of the layers for the nucleus with odd a; Etude comparee des desintegrations {beta} et du modele des couches pour les noyaux de a impair

    Energy Technology Data Exchange (ETDEWEB)

    Trocheris, M [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1953-07-01

    The systematic comparison of {beta} decays of the cores of number of odd mass with the predictions of the modal of Mrs. Mayer on spins and parities, has already been made by several authors. It is taken in the present work with more recent experimental data and with a method of classification of the {beta} transitions. A simultaneous comparison to the experience of the model of the layers and the theory of the {beta} transitions can serve to verify one and the other too. In the present work, it appeared more fruitful to try to verify the model of the layers with the help of the very established theory of the {beta} transitions. One will look to verify and perfect the models of the layers for transitions between fundamental states or isomers of the cores. (M.B.) [French] La comparaison systematique des desintegrations {beta} des noyaux de nombre de masse impair avec les predictions du modale de Mme MAYER sur les spins et les parites, a deja ete faite par plusieurs auteurs. Elle est reprise dans le present travail avec des donnees experimentales plus recentes et avec une methode de classification des transitions {beta}. Une comparaison simultanee a l'experience du modele des couches et de la theorie des transitions {beta} peut, a priori, servir a verifier egalement l'un et l'autre. Dans le present travail, il a paru plus fructueux de chercher a verifier le modele des couches a l'aide de la theorie bien etablie des transitions {beta}. On cherchera de verifier et de perfectionner le modele des couches pour les transitions entre etats fondamentaux ou isomeres des noyaux. (M.B.)

  13. CrusView: A Java-Based Visualization Platform for Comparative Genomics Analyses in Brassicaceae Species[OPEN

    Science.gov (United States)

    Chen, Hao; Wang, Xiangfeng

    2013-01-01

    In plants and animals, chromosomal breakage and fusion events based on conserved syntenic genomic blocks lead to conserved patterns of karyotype evolution among species of the same family. However, karyotype information has not been well utilized in genomic comparison studies. We present CrusView, a Java-based bioinformatic application utilizing Standard Widget Toolkit/Swing graphics libraries and a SQLite database for performing visualized analyses of comparative genomics data in Brassicaceae (crucifer) plants. Compared with similar software and databases, one of the unique features of CrusView is its integration of karyotype information when comparing two genomes. This feature allows users to perform karyotype-based genome assembly and karyotype-assisted genome synteny analyses with preset karyotype patterns of the Brassicaceae genomes. Additionally, CrusView is a local program, which gives its users high flexibility when analyzing unpublished genomes and allows users to upload self-defined genomic information so that they can visually study the associations between genome structural variations and genetic elements, including chromosomal rearrangements, genomic macrosynteny, gene families, high-frequency recombination sites, and tandem and segmental duplications between related species. This tool will greatly facilitate karyotype, chromosome, and genome evolution studies using visualized comparative genomics approaches in Brassicaceae species. CrusView is freely available at http://www.cmbb.arizona.edu/CrusView/. PMID:23898041

  14. Mesures de procédure spéciales et respect des droits de l'homme Rapport général

    NARCIS (Netherlands)

    Vervaele, J.A.E.

    2009-01-01

    Le but du rapport général est de mener une analyse comparative des rapports nationaux en vue de présenter les processus de transformation des systèmes de justice pénale internes, en particulier du procès pénal, étant donné que des mesures procédurales spéciales sont introduites pour appréhender le

  15. Spatial analysis of homicides in South East Brazil: An assessment of differential risk between men, women, and the youth / Analyse des homicides dans la région du Sud-Est du Brésil : une évaluation des risques différentiels chez les hommes, les femmes et les jeunes

    Directory of Open Access Journals (Sweden)

    Diniz Alves Alexandre Magno

    2012-10-01

    Full Text Available Cette étude se base sur une perspective géographique et analyse l’évolution dans l’espace et dans le temps des taux moyens de morts par homicide dans la région du Sud-Est du Brésil, entre 2001 et 2008, chez les hommes, les femmes, les jeunes entre 15 et 29 ans, et l’ensemble de la population. Les résultats mettent en évidence que ce phénomène touche de manière asymétrique les jeunes hommes, tandis que chez les femmes les taux moyens sont les plus bas. L’analyse dans l’espace a souligné qu’il existe des zones avec des taux d’homicide élevés et stabilisés dans le temps, comme les régions métropolitaines de Rio de Janeiro et Vitória. En revanche, l’étude a montré qu’entre les régions métropolitaines de Belo Horizonte (RMBH, Campinas et San Paolo, les dynamiques sont différentes. This study is based on a geographical perspective and explores the spatial and temporal evolution of average homicide rates in Southeast Brazil, between 2001 and 2008 for different subpopulations (male, female, youth, and total population. Results show that this phenomenon affects asymmetrically young males, while women have the lowest average rates. Spatial analysis pinpoints consolidated areas with high homicide rates, such as the metropolitan areas of Rio de Janeiro and Vitoria. On the other hand, different dynamics can be observed among the metropolitan areas of Belo Horizonte (BHMA, Campinas and Sao Paulo.

  16. Utilité du partage des corpus pour l'analyse des interactions en ligne en situation d'apprentissage : un exemple d'approche méthodologique autour d'une base de corpus d'apprentissage Benefits of Sharing Corpora when Analyzing Online Interactions: an Example of Methodology Related to a Databank of Learning and Teaching Corpora.

    Directory of Open Access Journals (Sweden)

    Maud Ciekanski

    2010-12-01

    Full Text Available La recherche sur les interactions en ligne en situation d'apprentissage offre encore trop peu souvent la possibilité d'accéder aux données à partir desquelles les chercheurs ont élaboré les analyses présentées dans les publications. Cela restreint, d'une part, la compréhension des phénomènes étudiés et, d'autre part, empêche toute réplication dans le but de comparaisons, d'analyses cumulatives ou contrastives. Dans le projet Mulce, nous défendons le point de vue méthodologique suivant : pour permettre une analyse des interactions situées, il convient de relier les différentes données issues de formations en ligne pour construire un objet d'analyse exploitable par différentes équipes et disciplines. Le constat actuel est que les données sont souvent décontextualisées, parcellaires ou simplement inaccessibles à la communauté des chercheurs. Nous proposons donc de structurer les données en corpus d'apprentissage (Letec de façon à rendre possible leur échange et la capitalisation des analyses. Le protocole de recherche, le scénario pédagogique, les interactions, productions et traces, les licences et les analyses capitalisables en sont les constituants. Cet article présente, dans un premier temps, les questionnements, à la fois théoriques, techniques et méthodologiques soulevés par la conception d'un tel projet. Dans un deuxième temps, nous illustrerons notre démarche à partir d'exemples issus des formations Simuligne et Copéas, en indiquant les processus simples de transformation du format Mulce aux formats requis par deux logiciels d'aide à l'analyse (l'un sur les forums, l'autre sur l'alignement entre vidéo et transcription. Nous insistons plus particulièrement sur l'intérêt de ces outils pour l'analyse des phénomènes de polyfocalisation et d'écriture multimodale dans l'analyse des interactions multimodales, caractéristiques des environnements d'apprentissage en ligne. Nous conclurons notre

  17. Probabilistic evaluation of scenarios in long-term safety analyses. Results of the project ISIBEL; Probabilistische Bewertung von Szenarien in Langzeitsicherheitsanalysen. Ergebnisse des Vorhabens ISIBEL

    Energy Technology Data Exchange (ETDEWEB)

    Buhmann, Dieter; Becker, Dirk-Alexander; Laggiard, Eduardo; Ruebel, Andre; Spiessl, Sabine; Wolf, Jens

    2016-07-15

    In the frame of the project ISIBEL deterministic analyses on the radiological consequences of several possible developments of the final repository were performed (VSG: preliminary safety analysis of the site Gorleben). The report describes the probabilistic evaluation of the VSG scenarios using uncertainty and sensitivity analyses. It was shown that probabilistic analyses are important to evaluate the influence of uncertainties. The transfer of the selected scenarios in computational cases and the used modeling parameters are discussed.

  18. Development of a measuring and evaluation method for X-ray analysis of residual stresses in the surface region of polycrystalline materials; Entwicklung eines Mess- und Auswerteverfahrens zur roentgenographischen Analyse des Eigenspannungszustandes im Oberflaechenbereich vielkristalliner Werkstoffe

    Energy Technology Data Exchange (ETDEWEB)

    Genzel, C.

    2000-11-01

    The topic of the habilitation thesis is the development of an X-ray diffraction method for measurement and depth-resolved analysis of internal stresses in the surface region of polycrystalline materials. The method relies on the basic approach of varying {tau}, the penetration depth of the X-rays in the materials, by the scattering vector g{sub theta{psi}} via stepwise specimen rotation. Thus, depth profiles of the interlattice plane distances d(hkl) in the specimen system can be derived for given direction and inclination angles {theta} and {psi} of the scattering vector. This offers the possibility to identify individual components of the stress tensors of the basic equation of the X-ray diffraction analysis, and to perform separate analyses of those components. For calculation of the relevant internal stress distributions {sigma}{sub ij}({tau}) using the interlattice plane distance profiles, a self-consistent method is established which takes into account the high sensitivity of the derived internal stresses in relation to the interlattice plane distance d{sub 0}(hkl) in the stress-free crystal lattice. The evaluation yields results describing the depth profiles as well as the strain-free interlattice plane distance d{sub 0}(hkl), so that a quantitative analysis is possible of tri-axial internal stress states in the surface region of the materials. (orig./CB) [German] Den Gegenstand der vorliegenden Arbeit bildet die Entwicklung eines roentgenographischen Mess- und Auswerteverfahrens zur tiefenaufgeloesten Analyse des oberflaechennahen Eigenspannungszustandes in vielkristallinen Werkstoffen. Der Grundgedanke der Methode besteht darin, die Eindringtiefe {tau} der Roentgenstrahlung in den Werkstoff durch schrittweise Drehung der Probe um den Streuvektor g{sub {theta}}{sub {psi}} zu variieren. Damit koennen Tiefenprofile der Netzebenenabstaende d(hkl) fuer fest vorgegebene Azimut- und Neigungswinkel {theta} und {psi} des Streuvektors im Probensystem ermittelt

  19. Du bon usage des sources en histoire culturelle: Analyse comparée des procès d'inquisition et des procès de béatification

    Directory of Open Access Journals (Sweden)

    Jean-Michel Sallmann

    1995-12-01

    Full Text Available This article discusses the issue of historical sources and their credibility. This can be addressed in a simple question: in what way is our perception of a phenomenon based on the source we use? Let us take as an example the judiciary archives: the reading of its documents reveal characteristics altered by the intervention of the judge, the clerck's transcription etc. To further illustrate the subject, the beatification and inquisition documents in southern Italy during the Modern Age are studied.

  20. Study of a micro-sublimation apparatus with removal of the vapours by pumping; application to the analysis of fluorinated products (1963); Etude d'un appareillage de microsublimation avec entrainement des vapeurs par pompage et application a l'analyse des produits fluores (1963)

    Energy Technology Data Exchange (ETDEWEB)

    Delvalle, P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1963-07-01

    Micro-sublimation analysis presents definite advantages both from the qualitative and quantitative points of view. An automatic micro-sublimation analysis apparatus has been developed for the analysis of fluorinated products (ClF{sub 3}, HF, UF{sub 6}, etc.) but this is only one particular application of a method which has a far wider field of possible applications. We give first the most favorable conditions for the operation of such an apparatus. These conditions are the use of a detector which is linear and independent of the nature of the gas, the flow of the sublimed vapours in the conditions of molecular flow, and finally a reproducible and linear re-heating of the separating trap. The apparatus thus built has the advantage of yielding any analysis without prior calibration. It also makes possible the easy identification of an unknown product by the determination of its vapour pressure curve and its molecular weight. The analysis of fluorinated products with this apparatus has shown that the experimental results agree well with what is expected. (author) [French] L'analyse par microsublimation presente un interet certain tant au point de vue qualitatif que quantitatif. Nous avons mis au point un appareillage automatique d'analyse par microsublimation pour l'analyse des produits fluores (CIF{sub 3}, HF, UF{sub 6}, etc.) mais il ne s'agit que de l'application a un cas particulier d'une methode ayant un champ d'applications bien plus vaste. Nous exposons tout d'abord les conditions les plus favorables au bon fonctionnement d'un tel appareil. Ces conditions sont l'emploi d'un detecteur lineaire et independant de la nature du gaz, l'ecoulement des vapeurs sublimees en regime moleculaire et enfin un rechauffage reproductible et lineaire du piege separateur. L'appareil ainsi realise presente l'avantage d'effectuer une analyse quelconque sans etalonnage prealable. Il permet en outre d'identifier aisement un corps inconnu par la determination de sa courbe de tension

  1. Numerical analysis of resonances induced by s wave neutrons in transmission time-of-flight experiments with a computer IBM 7094 II; Methodes d'analyse des resonances induites par les neutrons s dans les experiences de transmission par temps de vol et automatisation de ces methodes sur ordinateur IBM 7094 II

    Energy Technology Data Exchange (ETDEWEB)

    Corge, Ch [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1969-01-01

    Numerical analysis of transmission resonances induced by s wave neutrons in time-of-flight experiments can be achieved in a fairly automatic way on an IBM 7094/II computer. The involved computations are carried out following a four step scheme: 1 - experimental raw data are processed to obtain the resonant transmissions, 2 - values of experimental quantities for each resonance are derived from the above transmissions, 3 - resonance parameters are determined using a least square method to solve the over determined system obtained by equalling theoretical functions to the correspondent experimental values. Four analysis methods are gathered in the same code, 4 - graphical control of the results is performed. (author) [French] L'automatisation, sur ordinateur IBM 7094/II, de l'analyse des resonances induites par les neutrons s dans les experiences de transmission par temps de vol a ete accomplie en la decomposant selon un schema articule en quatre phases: 1 - le traitement des donnees experimentales brutes pour obtenir les transmissions interfero-resonnantes, 2 - la determination des grandeurs d'analyse a partir des transmissions precedentes, 3 - l'analyse proprement dite des resonances dont les parametres sont obtenus par la resolution d'un systeme surabondant. Quatre methodes d'analyse sont groupees en un meme programme, 4 - la procedure de verification graphique. (auteur)

  2. Numerical analysis of resonances induced by s wave neutrons in transmission time-of-flight experiments with a computer IBM 7094 II; Methodes d'analyse des resonances induites par les neutrons s dans les experiences de transmission par temps de vol et automatisation de ces methodes sur ordinateur IBM 7094 II

    Energy Technology Data Exchange (ETDEWEB)

    Corge, Ch. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1969-01-01

    Numerical analysis of transmission resonances induced by s wave neutrons in time-of-flight experiments can be achieved in a fairly automatic way on an IBM 7094/II computer. The involved computations are carried out following a four step scheme: 1 - experimental raw data are processed to obtain the resonant transmissions, 2 - values of experimental quantities for each resonance are derived from the above transmissions, 3 - resonance parameters are determined using a least square method to solve the over determined system obtained by equalling theoretical functions to the correspondent experimental values. Four analysis methods are gathered in the same code, 4 - graphical control of the results is performed. (author) [French] L'automatisation, sur ordinateur IBM 7094/II, de l'analyse des resonances induites par les neutrons s dans les experiences de transmission par temps de vol a ete accomplie en la decomposant selon un schema articule en quatre phases: 1 - le traitement des donnees experimentales brutes pour obtenir les transmissions interfero-resonnantes, 2 - la determination des grandeurs d'analyse a partir des transmissions precedentes, 3 - l'analyse proprement dite des resonances dont les parametres sont obtenus par la resolution d'un systeme surabondant. Quatre methodes d'analyse sont groupees en un meme programme, 4 - la procedure de verification graphique. (auteur)

  3. Binary analysis: 1. part: definitions and treatment of binary functions; 2. part: applications and functions of trans-coding; Analyse binaire: 1ere partie: definitions et traitements des fonctions binaires; 2eme partie: applications et fonctions de transcodage

    Energy Technology Data Exchange (ETDEWEB)

    Vallee, R L [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1968-07-01

    The study of binary groups under their mathematical aspects constitutes the matter of binary analysis, the purpose of which consists in developing altogether simple, rigorous and practical methods needed by the technicians, the engineers and all those who may be mainly concerned by digital processing. This subject, fast extending if not determining, however tends actually to play a main part in nuclear electronics as well as in several other research areas. (authors) [French] L'analyse binaire a pour objet l'etude mathematique des proprietes d'ensembles binaires algebriques et pour but l'elaboration de methodes simples, rigoureuses et pratiques, destinees aux techniciens, aux ingenieurs et a tous ceux qu'interesse directement le traitement numerique de l'information, discipline en expansion rapide qui, deja, en electronique nucleaire comme dans de nombreux autres domaines de la recherche, tend a jouer un role essentiel sinon determinant. (auteurs)

  4. Une mise en discussion autour du livre Socio-analyse des raisons d’agir. Études sur la liberté du sujet et de l’acteur de Guy Bajoit

    Directory of Open Access Journals (Sweden)

    Rachel Brahy

    2011-09-01

    Full Text Available I. Présentation de l’ouvrage et de “l’argument global”L’objectif que se donne la socio-analyse est d’« élucider les raisons pour lesquelles [des personnes] ont pris certaines décisions ou adopté certaines attitudes par lesquelles elles ont cherché à être sujets et acteurs de leur existence et à augmenter leur part de liberté par rapport aux contraintes sociales, culturelles et matérielles » (p. 89. A la suite de nombreux auteurs, Bajoit appuie l’idée que nous serions tous, dans les sociétés ...

  5. Fossil-based comparative analyses reveal ancient marine ancestry erased by extinction in ray-finned fishes.

    Science.gov (United States)

    Betancur-R, Ricardo; Ortí, Guillermo; Pyron, Robert Alexander

    2015-05-01

    The marine-freshwater boundary is a major biodiversity gradient and few groups have colonised both systems successfully. Fishes have transitioned between habitats repeatedly, diversifying in rivers, lakes and oceans over evolutionary time. However, their history of habitat colonisation and diversification is unclear based on available fossil and phylogenetic data. We estimate ancestral habitats and diversification and transition rates using a large-scale phylogeny of extant fish taxa and one containing a massive number of extinct species. Extant-only phylogenetic analyses indicate freshwater ancestry, but inclusion of fossils reveal strong evidence of marine ancestry in lineages now restricted to freshwaters. Diversification and colonisation dynamics vary asymmetrically between habitats, as marine lineages colonise and flourish in rivers more frequently than the reverse. Our study highlights the importance of including fossils in comparative analyses, showing that freshwaters have played a role as refuges for ancient fish lineages, a signal erased by extinction in extant-only phylogenies. © 2015 John Wiley & Sons Ltd/CNRS.

  6. Methodology for Analysing Energy Demand in Biogas Production Plants—A Comparative Study of Two Biogas Plants

    Directory of Open Access Journals (Sweden)

    Emma Lindkvist

    2017-11-01

    Full Text Available Biogas production through anaerobic digestion may play an important role in a circular economy because of the opportunity to produce a renewable fuel from organic waste. However, the production of biogas may require energy in the form of heat and electricity. Therefore, resource-effective biogas production must consider both biological and energy performance. For the individual biogas plant to improve its energy performance, a robust methodology to analyse and evaluate the energy demand on a detailed level is needed. Moreover, to compare the energy performance of different biogas plants, a methodology with a consistent terminology, system boundary and procedure is vital. The aim of this study was to develop a methodology for analysing the energy demand in biogas plants on a detailed level. In the methodology, the energy carriers are allocated to: (1 sub-processes (e.g., pretreatment, anaerobic digestion, gas cleaning, (2 unit processes (e.g., heating, mixing, pumping, lighting and (3 a combination of these. For a thorough energy analysis, a combination of allocations is recommended. The methodology was validated by applying it to two different biogas plants. The results show that the methodology is applicable to biogas plants with different configurations of their production system.

  7. A comparative study of cold- and warm-adapted Endonucleases A using sequence analyses and molecular dynamics simulations.

    Directory of Open Access Journals (Sweden)

    Davide Michetti

    Full Text Available The psychrophilic and mesophilic endonucleases A (EndA from Aliivibrio salmonicida (VsEndA and Vibrio cholera (VcEndA have been studied experimentally in terms of the biophysical properties related to thermal adaptation. The analyses of their static X-ray structures was no sufficient to rationalize the determinants of their adaptive traits at the molecular level. Thus, we used Molecular Dynamics (MD simulations to compare the two proteins and unveil their structural and dynamical differences. Our simulations did not show a substantial increase in flexibility in the cold-adapted variant on the nanosecond time scale. The only exception is a more rigid C-terminal region in VcEndA, which is ascribable to a cluster of electrostatic interactions and hydrogen bonds, as also supported by MD simulations of the VsEndA mutant variant where the cluster of interactions was introduced. Moreover, we identified three additional amino acidic substitutions through multiple sequence alignment and the analyses of MD-based protein structure networks. In particular, T120V occurs in the proximity of the catalytic residue H80 and alters the interaction with the residue Y43, which belongs to the second coordination sphere of the Mg2+ ion. This makes T120V an amenable candidate for future experimental mutagenesis.

  8. Mouvements transfrontaliers, migration des femmes et droits de la ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Jusqu'à récemment, les femmes ont été exclues des analyses de la migration, ou ont été perçues comme des personnes passives et dépendantes des migrants masculins ou comme des non-migrantes attendant le retour de leur mari. Toutefois, les chercheurs et les défenseurs des droits commencent à examiner le rôle ...

  9. Les representations sociales des musees par les jeunes de la ...

    African Journals Online (AJOL)

    La participation culturelle des jeunes reste un élément fondamental de la vie sociale. Ainsi, les musées sont des institutions culturelles qui contribuent à cette perspective. Mais, il est à constater que les visites muséales sont presque absentes des activités culturelles des jeunes. Le présent article propose une analyse des ...

  10. A comparative study between xerographic, computer-assisted overlay generation and animated-superimposition methods in bite mark analyses.

    Science.gov (United States)

    Tai, Meng Wei; Chong, Zhen Feng; Asif, Muhammad Khan; Rahmat, Rabiah A; Nambiar, Phrabhakaran

    2016-09-01

    This study was to compare the suitability and precision of xerographic and computer-assisted methods for bite mark investigations. Eleven subjects were asked to bite on their forearm and the bite marks were photographically recorded. Alginate impressions of the subjects' dentition were taken and their casts were made using dental stone. The overlays generated by xerographic method were obtained by photocopying the subjects' casts and the incisal edge outlines were then transferred on a transparent sheet. The bite mark images were imported into Adobe Photoshop® software and printed to life-size. The bite mark analyses using xerographically generated overlays were done by comparing an overlay to the corresponding printed bite mark images manually. In computer-assisted method, the subjects' casts were scanned into Adobe Photoshop®. The bite mark analyses using computer-assisted overlay generation were done by matching an overlay and the corresponding bite mark images digitally using Adobe Photoshop®. Another comparison method was superimposing the cast images with corresponding bite mark images employing the Adobe Photoshop® CS6 and GIF-Animator©. A score with a range of 0-3 was given during analysis to each precision-determining criterion and the score was increased with better matching. The Kruskal Wallis H test showed significant difference between the three sets of data (H=18.761, p<0.05). In conclusion, bite mark analysis using the computer-assisted animated-superimposition method was the most accurate, followed by the computer-assisted overlay generation and lastly the xerographic method. The superior precision contributed by digital method is discernible despite the human skin being a poor recording medium of bite marks. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  11. Analyse des conditions de travail des travailleurs intérimaires Analysis of the Working Conditions of Temporary Workers. Explaining These Workers’ Vulnerability to Occupational Accidents Análisis de las condiciones de trabajo de los trabajadores temporales. Cómo explicar la vulnerabilidad de estos trabajadores a los accidentes laborales ?

    Directory of Open Access Journals (Sweden)

    Rachid Belkacem

    2012-11-01

    Full Text Available Cet article analyse les conditions de travail des intérimaires. Il s’appuie sur les résultats d’une étude réalisée en 2008/2009 et financée par la Direction régionale du travail, de l’emploi et de la formation professionnelle – région Lorraine. Cette recherche a été organisée autour de deux travaux de terrain : une enquête par questionnaires et des entretiens semi-directifs menés auprès d’intérimaires détachés dans l’industrie et/ou le BTP. Cet article montre que la vulnérabilité des intérimaires aux accidents du travail est forte comparativement aux salariés permanents des entreprises. Cette dernière s’explique par des conditions de travail relativement plus difficiles. Ces travailleurs doivent s’adapter très souvent dans l’urgence à des contextes de travail différents et évolutifs.This paper analyzes the main characteristics of the working conditions of temporary workers in France. It examines the data from a large study conducted in 2008/2009 and financed by the Regional Labor Department of Lorraine (DRTEFP- Lorraine. Our research was organized around two surveys involving temporary workers in industry and/or construction and civil engineering. This article shows that temporary employees’ vulnerability to occupational accidents is higher than that of companies’ permanent employees. This vulnerability can be explained by relatively more difficult working conditions. Quite often, these workers must quickly adapt to different and evolving work contexts.Este artículo analiza las condiciones de trabajo de los trabajadores temporales en Francia. El mismo se apoya en los resultados de un estudio realizado en 2008/2009, financiado por la Dirección Regional del Trabajo, Empleo y Formación Profesional –Región Lorraine. Esta investigación ha sido organizada sobre la base de dos trabajos de terreno : encuesta y entrevistas a trabajadores temporales vinculados a la industria y/o al BTP. Este art

  12. Analyse pragma-énonciative des s/citations du site d’Arrêt sur images A pragma-enunciative analysis of quotations on the Web site Arrêt sur images (Freeze-frame

    Directory of Open Access Journals (Sweden)

    Alain Rabatel

    2010-04-01

    Full Text Available Cet article analyse différentes formes de citations dans les sites de presse sur le WEB, en prenant comme exemple le site d’Arrêt sur images. Après avoir analysé les deux grandes catégories d’enchâssements énonciatifs à l’œuvre sur le site et dégagé quelques spécificités du discours représenté/montré et du discours d’escorte qui commente le précédent, l’article montre que le discours d’escorte joue un rôle argumentatif majeur dans la mesure où il fait plus qu’inciter le lecteur à faire apparaître les citations, il les présente comme des éléments de preuve, bref, comme des citations à faire comparaître. La fonction rhétorico-argumentative de ces citations est confirmée par le procédé du montage, qui démonte les situations servant de support à une démonstration basée sur des preuves. Enfin, compte tenu du caractère médiacritique du site, le discours d’escorte construit un ethos de professionnalisme exigeant et une communauté discursive et interprétative soudée autour de valeurs partagées.This article analyzes different forms of quotation on Web press sites, using the site Arrêt sur images as an example. After analyzing the two large categories of enunciative embeddings at work on the site and identifying the marks of direct represented/shown discourse and accompanying discourse, it shows that accompanying discourse plays a major argumentative role in so far as it does more than incite the reader to display the quotations, it presents them as elements of proof, in short, as quotations to be summoned. The rhetoric-argumentative function of quotations is confirmed through the process of editing, which dissects the situation while serving as a support to demonstration. This editing rests on a circular logic of justification based on proof. At last, considering the media critical character of the site, the accompanying discourse constructs an ethos of demanding professionalism and a united

  13. Une analyse d’une production de discours rapporté : l’introduction des tours de parole dans “Hills Like White Elephants” d’Ernest Hemingway

    Directory of Open Access Journals (Sweden)

    Grégoire LACAZE

    2010-09-01

    Full Text Available Cette nouvelle d’Ernest Hemingway est construite principalement autour du report de paroles au discours direct des deux personnages principaux. Elle a déjà fait l’objet de nombreuses études critiques, notamment sur le style de son auteur. Nous nous intéressons ici à un aspect souvent négligé dans ces études, l’introduction du discours direct, car celle-ci nous semble relativement importante dans la réception1 de la nouvelle.À partir de cette production de discours rapporté, nous étudierons comment le narrateur choisit d’introduire les différents tours de parole. Cette réflexion, s’inscrivant dans une perspective énonciative, s’appuiera sur une étude grammaticale et sémantique prenant en compte les spécificités du genre de la nouvelle et leur influence sur les choix stylistiques de l’auteur. Une étude statistique sur la composition des structures d’introduction du discours des personnages viendra étayer l’analyse.Hemingway’s short story, “Hills Like White Elephants”, is largely built around a reported dialogue involving two main characters. Although many critical studies have been devoted to this short story, focusing especially on Hemingway’s style, this paper seeks to explore a relatively neglected theme, namely the introduction of direct speech, which acquires significant importance in the reception of the short story.Thanks to the dialogue that materializes as an occurrence of reported speech produced by a reporter, we will study how the narrator chooses to introduce the various turns constituting the dialogue. This analysis, inscribed within the framework of an enunciative approach, aims at pointing out the stylistic devices used by the author. Both linguistic and semantic aspects will be taken into account as well as the specificities induced by the genre of the short story and their influence on the stylistic choices made by the author. The analysis will be backed up with statistical data

  14. New developments in the analysis and measurement of thicknesses by excitation of the fluorescent lines by means of {beta} particles; Nouveaux developpements de l'analyse et de la mesure des epaisseurs par excitation des raies de fluorescence au moyen de particules {beta}

    Energy Technology Data Exchange (ETDEWEB)

    Martinelli, P [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires; Seibel, G [Institut de Recherches de la Siderurgie, 78 - Saint-Germain-en-Laye (France)

    1960-07-01

    The process for analysing and measuring the thickness of deposits by {beta}-X fluorescence which we have already described has undergone further development. The use of promethium-147 and krypton-85 sources makes it possible to reduce the background noise which is observed with strontium-90. We present the results obtained for various measurements of the thickness of metallic coatings and the continuous measurement of calcium and of iron in ore samples. We describe the tests carried out with a view to analysing the X-rays by means of a crystal. (author) [French] Le procede d'analyse et de mesure des epaisseurs de depots par fluorescence {beta}-X que nous avons precedemment decrit a fait l'objet de nouveaux developpements. L'emploi de sources de prometheum-147 et de krypton-85 permet de reduire le bruit de fond que l'on observe avec le strontium-90. Nous dormons les resultats obtenus pour diverses mesures d'epaisseurs de depots metalliques et la mesure en continu du calcium et du fer dans les carottes de minerais. Nous decrivons les essais effectues en vue d'analyser le rayonnement X au moyen d'un cristal. (auteur)

  15. Analyse des facteurs socioculturels et survenue des troubles musculosquelettiques : le cas des couturières en Tunisie Analysis of sociocultural factors and the onset of musculoskeletal disorders: the case of seamstresses in Tunisia Análisis de factores socio-culturales y aparición de problemas músculo-esqueléticos: el caso de las costureras en Túnez

    Directory of Open Access Journals (Sweden)

    Raouf Ghram

    2010-05-01

    Full Text Available Le contexte actuel de mondialisation implique parfois des délocalisations et une internationalisation du travail qui conduisent quelquefois à des situations de travail défavorables pour la préservation de la santé des travailleurs. En effet, les transferts de technologies nécessitent une compréhension des déterminants contextuels pouvant influencer les situations de travail. Nous y retrouvons notamment les spécificités socioculturelles que nous avons traitées dans cette recherche. La prise en considération de celles-ci nous a permis d’avoir une meilleure compréhension des situations de travail d’opératrices en confection en Tunisie. De fait, nous percevons l’intérêt de prendre en compte ces dimensions dans le but de concevoir des situations de travail adéquates respectueuses de la santé.The current context of globalization sometimes involves work relocation and internationalization, which sometimes lead to work situations unfavourable for the preservation of workers’ health. Indeed, technology transfers require an understanding of the contextual determining factors that can influence work situations. Here, we find in particular the sociocultural specificities that we addressed in this study. Their consideration provided us with a better understanding of operator work situations in the clothing industry in Tunisia. In fact, we note the interest in taking these aspects into consideration in order to plan appropriate work situations that respect health.El contexto actual de globalización implica en ocasiones deslocalizaciones y una internacionalización del trabajo, que conduce a veces a situaciones de trabajo desfavorables para la conservación de la salud de los trabajadores. En efecto, las transferencias de tecnologías requieren una comprensión de los factores del contexto que pueden influir en las situaciones de trabajo. Hay, en particular, las especificaciones socio-culturales que tratamos en esta investigaci

  16. Statistical analyses for the purpose of an early detection of global and regional climate change due to the anthropogenic greenhouse effect; Statistische Analysen zur Frueherkennung globaler und regionaler Klimaaenderungen aufgrund des anthropogenen Treibhauseffektes

    Energy Technology Data Exchange (ETDEWEB)

    Grieser, J.; Staeger, T.; Schoenwiese, C.D.

    2000-03-01

    The report answers the question where, why and how different climate variables have changed within the last 100 years. The analyzed variables are observed time series of temperature (mean, maximum, minimum), precipitation, air pressure, and water vapour pressure in a monthly resolution. The time series are given as station data and grid box data as well. Two kinds of time-series analysis are performed. The first is applied to find significant changes concerning mean and variance of the time series. Thereby also changes in the annual cycle and frequency of extreme events arise. The second approach is used to detect significant spatio-temporal patterns in the variations of climate variables, which are most likely driven by known natural and anthropogenic climate forcings. Furtheron, an estimation of climate noise allows to indicate regions where certain climate variables have changed significantly due to the enhanced anthropogenic greenhouse effect. (orig.) [German] Der Bericht gibt Antwort auf die Frage, wo sich welche Klimavariable wie und warum veraendert hat. Ausgangspunkt der Analyse sind huntertjaehrige Zeitreihen der Temperatur (Mittel, Maximum, Minimum), des Niederschlags, Luftdrucks und Wasserdampfpartialdrucks in monatlicher Aufloesung. Es wurden sowohl Stationsdaten als auch Gitterpunktdaten verwendet. Mit Hilfe der strukturorientierten Zeitreihenzerlegung wurden signifikankte Aenderungen im Mittel und in der Varianz der Zeitreihen gefunden. Diese betreffen auch Aenderungen im Jahresgang und in der Haeufigkeit extremer Ereignisse. Die ursachenorientierte Zeitreihenzerlegung selektiert signifikante raumzeitliche Variationen der Klimavariablen, die natuerlichen bzw. anthropogenen Klimaantrieben zugeordnet werden koennen. Eine Abschaetzung des Klimarauschens erlaubt darueber hinaus anzugeben, wo und wie signifikant der anthropogene Treibhauseffekt welche Klimavariablen veraendert hat. (orig.)

  17. Analyse de l'évolution et modélisation des besoins énergétiques français. Application du modèle ABEL à des scénarios contrastés aux horizons 2000 et 2020 Evolutionary Analysis and Modeling of French Energy Needs. Applying the ABEL Model to Contrasting Scenarios for the Horizons 2000 and 2020

    Directory of Open Access Journals (Sweden)

    Roncato J. P.

    2006-11-01

    Full Text Available Devant l'enchérissement du pétrole, les pays industrialisés à faibles ressources énergétiques fossiles nationales devront recourir dans le futur à d'autres formes d'énergie (nucléaire, charbon, solaire. La transformation de ces énergies primaires en vecteurs commercialisables est caractérisée par des coûts d'investissement élevés. Cela impose de rechercher le meilleur taux d'utilisation des équipements face à une demande fortement modulée. L'étude de tels systèmes énergétiques procède en deux étapes : analyse des besoins en énergie, puis optimisation des équipements depuis le niveau de production jusqu'à l'utilisation. L'objet de cette communication est de présenter un modèle d'étude de la consommation (ABEL, qui s'appuie sur une analyse du système socio-économique national expliquant la formation et l'évolution des besoins d'énergie. Cette analyse aboutit à la construction de modèles de simulation des consommations d'énergie par secteur. Cette modélisation rend compte des variations saisonnières des besoins. Un modèle macro-économique de cohérence traduit les relations entre niveaux d'activité des différents secteurs, de façon à éviter des distorsions grossières dans une projection à long terme. Des scénarios permettent de simuler diverses hypothèses de développement économique et social. Faced with increasing oil prices, the industrialized countries with smail national fossil energy resources will have to look to other types of energy in the future (nuclear energy, coal, solar energy. The transformation of such primary energy sources into marketable carriers is characterized by high investment costs. This means that the best utilization factor for equipment will have to be sought after in the face of highly modulated demand. A survey of such energy systems is made in two steps: (a analyzing energy needs, and (b optimizing equipment all the way from initial production to end use. The aim of

  18. Analyse économique de l’industrie photovoltaïque : mondialisation, dynamique des coûts, et politiques publiques

    OpenAIRE

    Du Fayet De La Tour , Arnaud

    2012-01-01

    In the last decade, the photovoltaic market was multiplied by 10, module price was reduced by 60%, and China increased its share in cell and module production from almost nothing to more than half. The purpose of this thesis is to shed light on the mechanisms driving these transformations. We analyse how China managed to acquire the photovoltaic technology, relying on interviews with actors of the Chinese photovoltaic industry, and data gathered on patents related to the photovoltaic technolo...

  19. Analyse de code et processus d'évaluation des composants sécurisés contre l'injection de faute

    OpenAIRE

    Dureuil , Louis

    2016-01-01

    Vulnerability detections for smart cards require state of the art methods both to attack and to protect the secure device. A typical type of attack is fault injection, most notably performed by means of laser techniques. To prevent some of the consequences of this kind of attacks, several analyses are conducted at the software level. Being able to define criteria and to propose automated tools that can survey the robustness of an application to fault injection is thus nowadays a hot topic, ev...

  20. Analytical studies by activation. Part A and B: Counting of short half-life radio-nuclides. Part C: Analytical programs for decay curves; Etudes d'analyse par activation. Parties A et B: le comptage des radio-nucleides de periodes courtes. Partie C: programme de depouillement des courbes de decroissance

    Energy Technology Data Exchange (ETDEWEB)

    Junod, E [Commissariat a l' Energie Atomique Grenoble (France). Centre d' Etudes Nucleaires

    1966-03-01

    est consacree au probleme des corrections de pertes au comptage dues au temps mort des analyseurs multicanaux. On a etabli les formules de correction exactes lorsque le radionucleide de periode courte est pur ou seulement accompagne d'un radionucleide de periode longue. Par comparaison on a trace sous forme d'abaques les approximations fournies par le comptage dit 'en temps actif' et par un mode de comptage en temps reel associe a la mesure du temps mort global, ce second procede se revelant plus valable que le premier. Dans le cas d'un melange complexe, on donne le moyen de le ramener au probleme a deux constituants. Partie C: On presente les problemes que pose l'analyse qualitative et quantitative des courbes de decroissance d'un melange de sources radioactives dont au moins une de periode courte. Six procedes fondamentaux sont decrits mathematiquement pour lesquels sont proposes des elements de programmes fortran. Deux programmes supplementaires sont construits pour traiter globalement des problemes de dosages en analyse par activation: l'un base sur l'irradiation simultanee d'un echantillon et d'un ou plusieurs temoins; l'autre sur l'irradiation separee de l'echantillon et du temoin, un dosimetre (par activation ou exterieur) servant a normaliser les conditions de flux d'irradiation.

  1. Mexsyco project: representation of power plan control-instrumentation functions. Bibliographical analysis and conclusions; Projet Mexsyco: representation des fonctions de controle-commande des centrales. Analyse bibliographique et conclusions

    Energy Technology Data Exchange (ETDEWEB)

    Brunet, M

    1994-03-01

    The study covered in this paper is designed to review the current situation in terms of functional analysis, in order to find a functional analysis method for mechanical parts able to serve as a substrate for expressing operating safety constraints, time-related performance or any other tag of function description. This paper comprises three parts: The first is devoted to general notions of the formats used by the various functional analyses. It attempts to explain the three types of format: behavioural, structural and functional. It tackles the notions of trees and bottom-up and top-down approaches. It proposes examining the link between the expected functions of the systems and the hardware supporting these functions. It attempts to make a distinction between ``operators`` and ``operands`` enabling the notion of object to be linked to that of the three types of format seen above. It ends with a reminder of the distinction between semi-formal and formal. The second part analyses the current situation of functional analysis of the mechanical and control-instrumentation parts of power production plants, through a bibliographical search. The results of this second part are however disappointing. The purpose of the third part of the study is a prototype format built up from the considerations of the first two parts. This format meets our requirements better than those of the bibliographical analysis, but it could doubtless be improved: application of this format to RCV highlights its advantages, but also underlines the improvements needed. Given the deadlines of the Mexsyco project, the decision was taken to suspend development of this format for the time being and use a method currently being produced and based on use of the current functional breakdown (basic plant systems) and of a modular tree-structure representation of the control-instrumentation of a basic plant system. (author). 12 refs., 4 annexes.

  2. Comparative transcriptome analyses of three medicinal Forsythia species and prediction of candidate genes involved in secondary metabolisms.

    Science.gov (United States)

    Sun, Luchao; Rai, Amit; Rai, Megha; Nakamura, Michimi; Kawano, Noriaki; Yoshimatsu, Kayo; Suzuki, Hideyuki; Kawahara, Nobuo; Saito, Kazuki; Yamazaki, Mami

    2018-05-07

    The three Forsythia species, F. suspensa, F. viridissima and F. koreana, have been used as herbal medicines in China, Japan and Korea for centuries and they are known to be rich sources of numerous pharmaceutical metabolites, forsythin, forsythoside A, arctigenin, rutin and other phenolic compounds. In this study, de novo transcriptome sequencing and assembly was performed on these species. Using leaf and flower tissues of F. suspensa, F. viridissima and F. koreana, 1.28-2.45-Gbp sequences of Illumina based pair-end reads were obtained and assembled into 81,913, 88,491 and 69,458 unigenes, respectively. Classification of the annotated unigenes in gene ontology terms and KEGG pathways was used to compare the transcriptome of three Forsythia species. The expression analysis of orthologous genes across all three species showed the expression in leaf tissues being highly correlated. The candidate genes presumably involved in the biosynthetic pathway of lignans and phenylethanoid glycosides were screened as co-expressed genes. They express highly in the leaves of F. viridissima and F. koreana. Furthermore, the three unigenes annotated as acyltransferase were predicted to be associated with the biosynthesis of acteoside and forsythoside A from the expression pattern and phylogenetic analysis. This study is the first report on comparative transcriptome analyses of medicinally important Forsythia genus and will serve as an important resource to facilitate further studies on biosynthesis and regulation of therapeutic compounds in Forsythia species.

  3. Comparative analyses reveal potential uses of Brachypodium distachyon as a model for cold stress responses in temperate grasses

    Directory of Open Access Journals (Sweden)

    Li Chuan

    2012-05-01

    Full Text Available Abstract Background Little is known about the potential of Brachypodium distachyon as a model for low temperature stress responses in Pooideae. The ice recrystallization inhibition protein (IRIP genes, fructosyltransferase (FST genes, and many C-repeat binding factor (CBF genes are Pooideae specific and important in low temperature responses. Here we used comparative analyses to study conservation and evolution of these gene families in B. distachyon to better understand its potential as a model species for agriculturally important temperate grasses. Results Brachypodium distachyon contains cold responsive IRIP genes which have evolved through Brachypodium specific gene family expansions. A large cold responsive CBF3 subfamily was identified in B. distachyon, while CBF4 homologs are absent from the genome. No B. distachyon FST gene homologs encode typical core Pooideae FST-motifs and low temperature induced fructan accumulation was dramatically different in B. distachyon compared to core Pooideae species. Conclusions We conclude that B. distachyon can serve as an interesting model for specific molecular mechanisms involved in low temperature responses in core Pooideae species. However, the evolutionary history of key genes involved in low temperature responses has been different in Brachypodium and core Pooideae species. These differences limit the use of B. distachyon as a model for holistic studies relevant for agricultural core Pooideae species.

  4. Analyse comparée de bassins sédimentaires transtensionnels : le bassin de Santa Rosalia (Basse Californie du Sud, Mexique et de Mendibelza (Pyrénées, France

    Directory of Open Access Journals (Sweden)

    Bourrouilh- Le Jan, F.

    2005-12-01

    Full Text Available Cet article présente un analyse comparée de bassins sédimentaires liés a l’ouverture en cours du Golfe de Californie, avec le bassin d’ouverture ancien, jurassico-crétacés de Mendibelza dans les Pyrénées occidentales par l’ouverture du Golfe de Gascogne. Ce travail est une contribution à la compréhension de la sédimentation et des contrôles de bassins transtensionnels situés sur des marges divergentes obliques actuelles, dans le but d’utiliser ces modèles et de les comparer, pour mieux comprendre et interpréter les bassins anciens créés dans des contextes géodynamiques analogues, mais qui sont tectonisés. Le fil directeur est l’analyse comparée de ces bassins : - dans leur évolution tectonique, leur modélisation géométrique et les contraintes auxquelles ils ont été soumis, - dans l’enregistrement sédimentaire (séquences des épisodes d’ouverture, des forçages tectoniques, climatiques et sédimentaires qui ont accompagné la naissance, l’évolution et la tectonisation de ces bassins (Mendibelza. Ainsi, le bassin de Santa Rosalia a enregistré les étapes d’évolution parallèles à la formation du rift oblique du Golfe de Californie depuis le Miocène supérieur suivant 3 séquences : T1 (Miocène supérieur-Pliocène inférieur représente la phase syn-rift constituée de faciès de fan-delta; T2 (Pliocène inférieur à moyen représente la transition du rifting-drifting, marquée par une rupture brusque de la sédimentation et constitué de faciès de fan-delta passant à plate forme; T3 (Pliocène supérieur-Pléistocène est un cortège de haut niveau marin, marquant une deuxième pulsation de la subsidence du bassin de Santa Rosalia pendant l’ouverture généralisée du Golfe de Californie. La formation de Mendibelza est constituée de 3 séquences : - la séquence inférieure K1 de l’Albien inférieur, formée de faciès de front-delta et pro-delta déposés pendant la phase Syn-rift. K2

  5. Routine Isotopic Analysis of {sup 235}U by Emission Spectrometry. 1. Interferometry using electrode-less discharge lamps 2. determination of the {sup 235}U/{sup 238}U ratio using a spectrograph and electrode-less lamps; Contribution a l'analyse isotopique de routine de l'uranium 235 par spectrometrie d'emission. 1. interferometrie avec des lampes a decharge sans electrode. 2. determination du rapport {sup 235}U/{sup 238}U a l'aide d'un spectrographe et avec des lampes sans electrodes

    Energy Technology Data Exchange (ETDEWEB)

    Capitini, R; Ceccaldi, M; Leicknam, J P; Rabec, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1970-07-01

    acceptable accuracy by using a photographic plate spectrograph which has not undergone any modification; the isotopic lines used are located at 4.244 A. By carrying out a certain number of corrections necessitated by the very rich nature of the uranium spectrum, it is shown that it is possible to carry out isotopic analyses with a relative accuracy of about 2.5 to 3.0 per cent in the neighbourhood of the natural abundance; this accuracy can reach and exceed 1 per cent for samples enriched in the 235 isotope. These results, for routine determinations, are close to those which can be obtained with grating or interferometric equipment, which follows the isotopic lines simultaneously. (author) [French] I. Nous avons utilise l'appareil interferometrique ''HYPEAC'' pour le dosage de routine de l'uranium 235. Pour faciliter l'examen des echantillons non metalliques et reduire la duree des analyses, on est conduit a substituer des lampes a decharge sans electrode aux sources de lumiere a cathode creuse habituellement utilisees. La preparation hors de l'appareil de telles lampes contenant du tetrachlorure d'uranium est decrite; elle est aisee et rapide: une heure et demie environ pour chacune, plusieurs sources pouvant etre fabriquees simultanement, ce qui reduit encore la duree totale de chaque analyse. Chaque determination ne necessite que quelques milligrammes d'echantillon. Pour pallier l'effet de dereglages optiques spontanes qui empechent d'appliquer la methode de determination habituelle des abondances isotopiques, on est conduit a comparer les spectres des echantillons a ceux d'etalons, tous ces spectres etant enregistres successivement et alternativement. Une serie d'exemples de determinations portant sur plus de 150 mesures est presentee et discutee. Avec des echantillons dont les abondances sont voisines de celle de l'uranium naturel et jusqu'a 5 pour cent environ en isotope 235, la reproductibilite des mesures est voisine de 2 pour cent, la precision relative etant de

  6. Characterization of Aeromonas hydrophila Wound Pathotypes by Comparative Genomic and Functional Analyses of Virulence Genes

    Science.gov (United States)

    Grim, Christopher J.; Kozlova, Elena V.; Sha, Jian; Fitts, Eric C.; van Lier, Christina J.; Kirtley, Michelle L.; Joseph, Sandeep J.; Read, Timothy D.; Burd, Eileen M.; Tall, Ben D.; Joseph, Sam W.; Horneman, Amy J.; Chopra, Ashok K.; Shak, Joshua R.

    2013-01-01

    ABSTRACT Aeromonas hydrophila has increasingly been implicated as a virulent and antibiotic-resistant etiologic agent in various human diseases. In a previously published case report, we described a subject with a polymicrobial wound infection that included a persistent and aggressive strain of A. hydrophila (E1), as well as a more antibiotic-resistant strain of A. hydrophila (E2). To better understand the differences between pathogenic and environmental strains of A. hydrophila, we conducted comparative genomic and functional analyses of virulence-associated genes of these two wound isolates (E1 and E2), the environmental type strain A. hydrophila ATCC 7966T, and four other isolates belonging to A. aquariorum, A. veronii, A. salmonicida, and A. caviae. Full-genome sequencing of strains E1 and E2 revealed extensive differences between the two and strain ATCC 7966T. The more persistent wound infection strain, E1, harbored coding sequences for a cytotoxic enterotoxin (Act), a type 3 secretion system (T3SS), flagella, hemolysins, and a homolog of exotoxin A found in Pseudomonas aeruginosa. Corresponding phenotypic analyses with A. hydrophila ATCC 7966T and SSU as reference strains demonstrated the functionality of these virulence genes, with strain E1 displaying enhanced swimming and swarming motility, lateral flagella on electron microscopy, the presence of T3SS effector AexU, and enhanced lethality in a mouse model of Aeromonas infection. By combining sequence-based analysis and functional assays, we characterized an A. hydrophila pathotype, exemplified by strain E1, that exhibited increased virulence in a mouse model of infection, likely because of encapsulation, enhanced motility, toxin secretion, and cellular toxicity. PMID:23611906

  7. An Appraisal of Analytical Methods for Plutonium and their Applications to the Analysis of Nuclear Materials; Evaluation des Methodes Analytiques de Dosage du Plutonium et de Leur Application a l'Analyse des Matieres Nucleaires; Otsenka analiticheskikh metodov opredeleniya plutoniya i ikh primenenie dlya analiza yadernykh materialov; Metodos Analiticos de Determinacion del Plutonio y su Empleo en el Analisis de Materiales Nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Milner, G. W.C.; Phillips, G. [Atomic Energy Research Establishment, Harwell, Berks. (United Kingdom)

    1966-02-15

    programmes for new nuclear fuels. (author) [French] Il existe plusieurs methodes de dosage de la teneur en plutonium des matieres nucleaires. Pour les quantites de l'ordre du milligramme, les methodes utilisables sont la spectro- photometiie differentielle fondee sur la couleur de Pu (III), la gravimetrie fondee sur PuO{sub 2}, le comptage gamma et les methodes de reduction/oxydation comprenant les titrages poientiometriques et amperemetriques et la coulombmetrie a potentiel constant. Pour les quantites de Tordre du microgramme, le comptage alpha, la dilution isotopique et les methodes polarigraphiques sont a utiliser. Certaines methodes conviennent mieux que d'autres a des types determines d'echantillons et l'analyste soucieux d'obtenir les meilleurs resultats se heurte a un choix difficile. Les auteurs exposent les avantages et les inconvenients des methodes citees tels qu'ils se sont degages de l'experience acquise au cours des annees a l'Atomic Energy Research Establishment, et ils discutent l'exactitude, la precision, la sensibilite de ces methodes, et d'autres caracteristiques presentant un interet particulier. Certaines methodes ne peuvent etre utilisees si l'on n'a, dans une certaine mesure, separe le plutonium des autres constituants de l'echantillon et le memoire commente l'experience acquise avec l'echange d'anions et les procedes de chromatographie a phase inversee utilises a cette fin, en insistant surtout sur la mesure dans laquelle cette methode convient aux echantillons radioactifs. Les auteurs etudient en outre les nombreux problemes qui se sont poses lors de l'application (d'ailleurs couronnee de succes) de ces methodes a l'analyse des alliages de plutonium, des ceramiques et des cermets dans differentes combinaisons contenant de l'uranium, du thorium, du fer, du chrome, du molybdene, du cerium et du cobalt. Us exposent les difficultes de la dissolution des echantillons et de la reduction du plutonium a l'etat de valence voulu, ainsi que les avantages

  8. Comparative Physiological and Molecular Analyses of Two Contrasting Flue-Cured Tobacco Genotypes under Progressive Drought Stress

    Directory of Open Access Journals (Sweden)

    Xinhong Su

    2017-05-01

    Full Text Available Drought is a major environmental factor that limits crop growth and productivity. Flue-cured tobacco (Nicotiana tabacum is one of the most important commercial crops worldwide and its productivity is vulnerable to drought. However, comparative analyses of physiological, biochemical and gene expression changes in flue-cured tobacco varieties differing in drought tolerance under long-term drought stress are scarce. In this study, drought stress responses of two flue-cured tobacco varieties, LJ851 and JX6007, were comparatively studied at the physiological and transcriptional levels. After exposing to progressive drought stress, the drought-tolerant LJ851 showed less growth inhibition and chlorophyll reduction than the drought-sensitive JX6007. Moreover, higher antioxidant enzyme activities and lower levels of H2O2, Malondialdehyde (MDA, and electrolyte leakage after drought stress were found in LJ851 when compared with JX6007. Further analysis showed that LJ851 plants had much less reductions than the JX6007 in the net photosynthesis rate and stomatal conductance during drought stress; indicating that LJ851 had better photosynthetic performance than JX6007 during drought. In addition, transcriptional expression analysis revealed that LJ851 exhibited significantly increased transcripts of several categories of drought-responsive genes in leaves and roots under drought conditions. Together, these results indicated that LJ851 was more drought-tolerant than JX6007 as evidenced by better photosynthetic performance, more powerful antioxidant system, and higher expression of stress defense genes during drought stress. This study will be valuable for the development of novel flue-cured tobacco varieties with improved drought tolerance by exploitation of natural genetic variations in the future.

  9. Impact of vaccine herd-protection effects in cost-effectiveness analyses of childhood vaccinations. A quantitative comparative analysis.

    Science.gov (United States)

    Holubar, Marisa; Stavroulakis, Maria Christina; Maldonado, Yvonne; Ioannidis, John P A; Contopoulos-Ioannidis, Despina

    2017-01-01

    Inclusion of vaccine herd-protection effects in cost-effectiveness analyses (CEAs) can impact the CEAs-conclusions. However, empirical epidemiologic data on the size of herd-protection effects from original studies are limited. We performed a quantitative comparative analysis of the impact of herd-protection effects in CEAs for four childhood vaccinations (pneumococcal, meningococcal, rotavirus and influenza). We considered CEAs reporting incremental-cost-effectiveness-ratios (ICERs) (per quality-adjusted-life-years [QALY] gained; per life-years [LY] gained or per disability-adjusted-life-years [DALY] avoided), both with and without herd protection, while keeping all other model parameters stable. We calculated the size of the ICER-differences without vs with-herd-protection and estimated how often inclusion of herd-protection led to crossing of the cost-effectiveness threshold (of an assumed societal-willingness-to-pay) of $50,000 for more-developed countries or X3GDP/capita (WHO-threshold) for less-developed countries. We identified 35 CEA studies (20 pneumococcal, 4 meningococcal, 8 rotavirus and 3 influenza vaccines) with 99 ICER-analyses (55 per-QALY, 27 per-LY and 17 per-DALY). The median ICER-absolute differences per QALY, LY and DALY (without minus with herd-protection) were $15,620 (IQR: $877 to $48,376); $54,871 (IQR: $787 to $115,026) and $49 (IQR: $15 to $1,636) respectively. When the target-vaccination strategy was not cost-saving without herd-protection, inclusion of herd-protection always resulted in more favorable results. In CEAs that had ICERs above the cost-effectiveness threshold without herd-protection, inclusion of herd-protection led to crossing of that threshold in 45% of the cases. This impacted only CEAs for more developed countries, as all but one CEAs for less developed countries had ICERs below the WHO-cost-effectiveness threshold even without herd-protection. In several analyses, recommendation for the adoption of the target

  10. Analyse qualitative de l'intégration de l'éducation sexuelle des jeunes dans les médias audio-visuels à Kinshasa en République Démocratique du Congo.

    OpenAIRE

    Nsakala, Gabriel Vodiena; Coppieters, Yves; Kayembe, Patrick Kalambayi

    2014-01-01

    L'éducation sexuelle par les médias de masse contribue positivement à la prévention des infections sexuellement transmissibles (IST)/VIH et des grossesses précoces auprès des jeunes. L'objectifs de cette étude sont d'appréhender le niveau d'intégration de l'éducation sexuelle dans les émissions de santé à Kinshasa en République Démocratique du Congo et d'identifier les facteurs facilitant et limitant l'éducation sexuelle des jeunes dans les programmes audio-visuels congolais. Une triangulatio...

  11. L’éducation à la gestion des risques naturels dans le manuel de géographie de la 1ère année secondaire en Tunisie : analyse didactique et propositions

    OpenAIRE

    Harzalli, Fadhel

    2016-01-01

    L’introduction de l’éducation à la gestion des risques naturels dans les programmes et les manuels est récente dans l’enseignement de la géographie en Tunisie. En effet, l’éducation à la gestion des risques peut être considérée comme un champ éducatif émergeant et un ensemble d’interventions qui vise à informer, motiver et aider les apprenants à adopter volontairement des comportements favorables à la vie, et à se construire une opinion raisonnée sur des questions vives où l’intime et le soci...

  12. Apport des analyses isotopiques et moléculaires pour la caractérisation des communautés fonctionnelles et des voies métaboliques au cours de la méthanogenèse dans des boues d'épuration

    Directory of Open Access Journals (Sweden)

    Driss Limam, R.

    2015-01-01

    Full Text Available Characterization of functional communities and metabolic pathways during methanogenesis in wastewater sludge by isotopic and molecular analysis. Description of the subject. Investigation of the relationships between methanogenic community and metabolic pathway dynamics during methanogenesis. Objectives. The objective was to use an isotopic approach coupled with molecular analysis to identify metabolisms and to understand the dynamics of Archaea under different temperature conditions. Method. Sludge was incubated anaerobically under mesophilic and thermophilic conditions. Biogas production was monitored, together with stable isotopic signatures of produced CH4 and CO2. Results. Isotopic signature values for CH4 indicated a change in methanogenic metabolism with time and temperature. CH4 was predominantly produced from H2/CO2 and acetoclastic metabolism at the beginning of the mesophilic incubations and after acetate injection. A progressive shift towards an acetoclastic metabolism was observed at the end of mesophilic incubations. This period was associated with stability within archaeal communities as monitored by automated ribosomal intergenic spacer analysis (ARISA and FISH with oligonucleotidic probes targeting specifically the Archaea 16S rRNA gene. At the beginning of the thermophilic incubations and after acetate injection, methane was generated mostly from H2/CO2. At the end of the thermophilic incubations, an acetoclastic metabolism was observed and intergenic spacer analysis (ARISA and FISH showed important shifts in archaeal communities. Conclusions. Isotopic methods coupled with molecular analyses enabled us to better understand methanogenesis and the involvement of archaeal populations, which varied according to temperature. We also observed a preadaptation of archaeal communities in thermophilic conditions, which could be due to the fact that mesophilic microorganisms were progressively eliminated during the thermophilic incubation

  13. Cartographie des zones d'intervention des partenaires techniques et ...

    African Journals Online (AJOL)

    cartographier les zones d'intervention des partenaires techniques et financiers au Bénin. L'approche méthodologique utilisée a consisté à la recherche documentaire, à la collecte de données auprès des partenaires techniques et financiers et à l'analyse de ces données. Les résultats ont permis de constater que cent dix ...

  14. Reliance, liance et alliance : opérationnalité des concepts dans l'analyse du climat socio-relationnel de groupes restreints d'apprentissage en ligne

    Directory of Open Access Journals (Sweden)

    Jean-Jacques Quintin

    2010-10-01

    Full Text Available La recherche que nous présentons ici se donne pour but de mesurer le lien entre le "climat socio-relationnel" d'un groupe restreint engagé dans un travail collaboratif en ligne et la qualité des travaux collectifs produits. La démarche méthodologique adoptée, basée sur une analyse des échanges asynchrones entre les membres d'un groupe, nous permet d'aboutir à un modèle opératoire qui fait état des composantes du "climat socio-relationnel" susceptibles d'expliquer les résultats d'apprentissage obtenus. Deux notions – dérivées du concept sociologique de reliance – seront mobilisées : la liance et l'alliance. La première rend compte de la qualité de la relation (la chaleur, l'intimité, les émotions… qui se crée entre les interlocuteurs au cours de leurs échanges asynchrones. La seconde traduit la manière dont les participants confortent leur contrat d'association en vue de la réalisation du travail commun, afin de répondre aux exigences pédagogiques fixées. Les résultats de cette recherche montrent que, dans notre situation d'étude, le modèle de la reliance explique une part substantielle de la qualité moyenne des produits de l'apprentissage collectif et possède une homogénéité interne non négligeable. Ces éléments concourent à étayer l'assise conceptuelle et le caractère opératoire du modèle présenté.The aim of the research we are presenting here is to measure the link between the "socio-relational climate" of a small group in a collaborative work environment and the quality of the collective work they provide. The methodological approach adopted, based on an analysis of the asynchronous exchanges between members of a group, allows us to find a procedure that takes stock of some components of "socio-relational climate" that could account for the results in terms of learning. Two notions – derivatives of the sociological concept "reliance" – will be called upon: "liance" and "alliance". The

  15. Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks

    Science.gov (United States)

    Glicksberg, Benjamin S.; Li, Li; Badgeley, Marcus A.; Shameer, Khader; Kosoy, Roman; Beckmann, Noam D.; Pho, Nam; Hakenberg, Jörg; Ma, Meng; Ayers, Kristin L.; Hoffman, Gabriel E.; Dan Li, Shuyu; Schadt, Eric E.; Patel, Chirag J.; Chen, Rong; Dudley, Joel T.

    2016-01-01

    Motivation: Underrepresentation of racial groups represents an important challenge and major gap in phenomics research. Most of the current human phenomics research is based primarily on European populations; hence it is an important challenge to expand it to consider other population groups. One approach is to utilize data from EMR databases that contain patient data from diverse demographics and ancestries. The implications of this racial underrepresentation of data can be profound regarding effects on the healthcare delivery and actionability. To the best of our knowledge, our work is the first attempt to perform comparative, population-scale analyses of disease networks across three different populations, namely Caucasian (EA), African American (AA) and Hispanic/Latino (HL). Results: We compared susceptibility profiles and temporal connectivity patterns for 1988 diseases and 37 282 disease pairs represented in a clinical population of 1 025 573 patients. Accordingly, we revealed appreciable differences in disease susceptibility, temporal patterns, network structure and underlying disease connections between EA, AA and HL populations. We found 2158 significantly comorbid diseases for the EA cohort, 3265 for AA and 672 for HL. We further outlined key disease pair associations unique to each population as well as categorical enrichments of these pairs. Finally, we identified 51 key ‘hub’ diseases that are the focal points in the race-centric networks and of particular clinical importance. Incorporating race-specific disease comorbidity patterns will produce a more accurate and complete picture of the disease landscape overall and could support more precise understanding of disease relationships and patient management towards improved clinical outcomes. Contacts: rong.chen@mssm.edu or joel.dudley@mssm.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:27307606

  16. Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks.

    Science.gov (United States)

    Glicksberg, Benjamin S; Li, Li; Badgeley, Marcus A; Shameer, Khader; Kosoy, Roman; Beckmann, Noam D; Pho, Nam; Hakenberg, Jörg; Ma, Meng; Ayers, Kristin L; Hoffman, Gabriel E; Dan Li, Shuyu; Schadt, Eric E; Patel, Chirag J; Chen, Rong; Dudley, Joel T

    2016-06-15

    Underrepresentation of racial groups represents an important challenge and major gap in phenomics research. Most of the current human phenomics research is based primarily on European populations; hence it is an important challenge to expand it to consider other population groups. One approach is to utilize data from EMR databases that contain patient data from diverse demographics and ancestries. The implications of this racial underrepresentation of data can be profound regarding effects on the healthcare delivery and actionability. To the best of our knowledge, our work is the first attempt to perform comparative, population-scale analyses of disease networks across three different populations, namely Caucasian (EA), African American (AA) and Hispanic/Latino (HL). We compared susceptibility profiles and temporal connectivity patterns for 1988 diseases and 37 282 disease pairs represented in a clinical population of 1 025 573 patients. Accordingly, we revealed appreciable differences in disease susceptibility, temporal patterns, network structure and underlying disease connections between EA, AA and HL populations. We found 2158 significantly comorbid diseases for the EA cohort, 3265 for AA and 672 for HL. We further outlined key disease pair associations unique to each population as well as categorical enrichments of these pairs. Finally, we identified 51 key 'hub' diseases that are the focal points in the race-centric networks and of particular clinical importance. Incorporating race-specific disease comorbidity patterns will produce a more accurate and complete picture of the disease landscape overall and could support more precise understanding of disease relationships and patient management towards improved clinical outcomes. rong.chen@mssm.edu or joel.dudley@mssm.edu Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.

  17. Comparative analyses of plastid sequences between native and introduced populations of aquatic weeds Elodea canadensis and E. nuttallii.

    Directory of Open Access Journals (Sweden)

    Tea Huotari

    Full Text Available Non-indigenous species (NIS are species living outside their historic or native range. Invasive NIS often cause severe environmental impacts, and may have large economical and social consequences. Elodea (Hydrocharitaceae is a New World genus with at least five submerged aquatic angiosperm species living in fresh water environments. Our aim was to survey the geographical distribution of cpDNA haplotypes within the native and introduced ranges of invasive aquatic weeds Elodea canadensis and E. nuttallii and to reconstruct the spreading histories of these invasive species. In order to reveal informative chloroplast (cp genome regions for phylogeographic analyses, we compared the plastid sequences of native and introduced individuals of E. canadensis. In total, we found 235 variable sites (186 SNPs, 47 indels and two inversions between the two plastid sequences consisting of 112,193 bp and developed primers flanking the most variable genomic areas. These 29 primer pairs were used to compare the level and pattern of intraspecific variation within E. canadensis to interspecific variation between E. canadensis and E. nuttallii. Nine potentially informative primer pairs were used to analyze the phylogeographic structure of both Elodea species, based on 70 E. canadensis and 25 E. nuttallii individuals covering native and introduced distributions. On the whole, the level of variation between the two Elodea species was 53% higher than that within E. canadensis. In our phylogeographic analysis, only a single haplotype was found in the introduced range in both species. These haplotypes H1 (E. canadensis and A (E. nuttallii were also widespread in the native range, covering the majority of native populations analyzed. Therefore, we were not able to identify either the geographic origin of the introduced populations or test the hypothesis of single versus multiple introductions. The divergence between E. canadensis haplotypes was surprisingly high, and future

  18. Comparative analyses of plastid sequences between native and introduced populations of aquatic weeds Elodea canadensis and E. nuttallii.

    Science.gov (United States)

    Huotari, Tea; Korpelainen, Helena

    2013-01-01

    Non-indigenous species (NIS) are species living outside their historic or native range. Invasive NIS often cause severe environmental impacts, and may have large economical and social consequences. Elodea (Hydrocharitaceae) is a New World genus with at least five submerged aquatic angiosperm species living in fresh water environments. Our aim was to survey the geographical distribution of cpDNA haplotypes within the native and introduced ranges of invasive aquatic weeds Elodea canadensis and E. nuttallii and to reconstruct the spreading histories of these invasive species. In order to reveal informative chloroplast (cp) genome regions for phylogeographic analyses, we compared the plastid sequences of native and introduced individuals of E. canadensis. In total, we found 235 variable sites (186 SNPs, 47 indels and two inversions) between the two plastid sequences consisting of 112,193 bp and developed primers flanking the most variable genomic areas. These 29 primer pairs were used to compare the level and pattern of intraspecific variation within E. canadensis to interspecific variation between E. canadensis and E. nuttallii. Nine potentially informative primer pairs were used to analyze the phylogeographic structure of both Elodea species, based on 70 E. canadensis and 25 E. nuttallii individuals covering native and introduced distributions. On the whole, the level of variation between the two Elodea species was 53% higher than that within E. canadensis. In our phylogeographic analysis, only a single haplotype was found in the introduced range in both species. These haplotypes H1 (E. canadensis) and A (E. nuttallii) were also widespread in the native range, covering the majority of native populations analyzed. Therefore, we were not able to identify either the geographic origin of the introduced populations or test the hypothesis of single versus multiple introductions. The divergence between E. canadensis haplotypes was surprisingly high, and future research may

  19. Comparative sequence and structural analyses of G-protein-coupled receptor crystal structures and implications for molecular models.

    Directory of Open Access Journals (Sweden)

    Catherine L Worth

    Full Text Available BACKGROUND: Up until recently the only available experimental (high resolution structure of a G-protein-coupled receptor (GPCR was that of bovine rhodopsin. In the past few years the determination of GPCR structures has accelerated with three new receptors, as well as squid rhodopsin, being successfully crystallized. All share a common molecular architecture of seven transmembrane helices and can therefore serve as templates for building molecular models of homologous GPCRs. However, despite the common general architecture of these structures key differences do exist between them. The choice of which experimental GPCR structure(s to use for building a comparative model of a particular GPCR is unclear and without detailed structural and sequence analyses, could be arbitrary. The aim of this study is therefore to perform a systematic and detailed analysis of sequence-structure relationships of known GPCR structures. METHODOLOGY: We analyzed in detail conserved and unique sequence motifs and structural features in experimentally-determined GPCR structures. Deeper insight into specific and important structural features of GPCRs as well as valuable information for template selection has been gained. Using key features a workflow has been formulated for identifying the most appropriate template(s for building homology models of GPCRs of unknown structure. This workflow was applied to a set of 14 human family A GPCRs suggesting for each the most appropriate template(s for building a comparative molecular model. CONCLUSIONS: The available crystal structures represent only a subset of all possible structural variation in family A GPCRs. Some GPCRs have structural features that are distributed over different crystal structures or which are not present in the templates suggesting that homology models should be built using multiple templates. This study provides a systematic analysis of GPCR crystal structures and a consistent method for identifying

  20. Comparative sequence and structural analyses of G-protein-coupled receptor crystal structures and implications for molecular models.

    Science.gov (United States)

    Worth, Catherine L; Kleinau, Gunnar; Krause, Gerd

    2009-09-16

    Up until recently the only available experimental (high resolution) structure of a G-protein-coupled receptor (GPCR) was that of bovine rhodopsin. In the past few years the determination of GPCR structures has accelerated with three new receptors, as well as squid rhodopsin, being successfully crystallized. All share a common molecular architecture of seven transmembrane helices and can therefore serve as templates for building molecular models of homologous GPCRs. However, despite the common general architecture of these structures key differences do exist between them. The choice of which experimental GPCR structure(s) to use for building a comparative model of a particular GPCR is unclear and without detailed structural and sequence analyses, could be arbitrary. The aim of this study is therefore to perform a systematic and detailed analysis of sequence-structure relationships of known GPCR structures. We analyzed in detail conserved and unique sequence motifs and structural features in experimentally-determined GPCR structures. Deeper insight into specific and important structural features of GPCRs as well as valuable information for template selection has been gained. Using key features a workflow has been formulated for identifying the most appropriate template(s) for building homology models of GPCRs of unknown structure. This workflow was applied to a set of 14 human family A GPCRs suggesting for each the most appropriate template(s) for building a comparative molecular model. The available crystal structures represent only a subset of all possible structural variation in family A GPCRs. Some GPCRs have structural features that are distributed over different crystal structures or which are not present in the templates suggesting that homology models should be built using multiple templates. This study provides a systematic analysis of GPCR crystal structures and a consistent method for identifying suitable templates for GPCR homology modelling that will

  1. The complete chloroplast genome sequences of Lychnis wilfordii and Silene capitata and comparative analyses with other Caryophyllaceae genomes.

    Science.gov (United States)

    Kang, Jong-Soo; Lee, Byoung Yoon; Kwak, Myounghai

    2017-01-01

    The complete chloroplast genomes of Lychnis wilfordii and Silene capitata were determined and compared with ten previously reported Caryophyllaceae chloroplast genomes. The chloroplast genome sequences of L. wilfordii and S. capitata contain 152,320 bp and 150,224 bp, respectively. The gene contents and orders among 12 Caryophyllaceae species are consistent, but several microstructural changes have occurred. Expansion of the inverted repeat (IR) regions at the large single copy (LSC)/IRb and small single copy (SSC)/IR boundaries led to partial or entire gene duplications. Additionally, rearrangements of the LSC region were caused by gene inversions and/or transpositions. The 18 kb inversions, which occurred three times in different lineages of tribe Sileneae, were thought to be facilitated by the intermolecular duplicated sequences. Sequence analyses of the L. wilfordii and S. capitata genomes revealed 39 and 43 repeats, respectively, including forward, palindromic, and reverse repeats. In addition, a total of 67 and 56 simple sequence repeats were discovered in the L. wilfordii and S. capitata chloroplast genomes, respectively. Finally, we constructed phylogenetic trees of the 12 Caryophyllaceae species and two Amaranthaceae species based on 73 protein-coding genes using both maximum parsimony and likelihood methods.

  2. Soil microbial community structure in diverse land use systems:A comparative study using Biolog,DGGE,and PLFA analyses

    Institute of Scientific and Technical Information of China (English)

    XUE Dong; YAO Huai-Ying; GE De-Yong; HUANG Chang-Yong

    2008-01-01

    Biolog,16S rRNA gene denaturing gradient gel electrophoresis (DGGE),and phospholipid fatty acid (PLFA) analyses were used to assess soil microbial community characteristics in a chronosequence of tea garden systems (8-,50-,and 90year-old tea gardens),an adjacent wasteland,and a 90-year-old forest.Biolog analysis showed that the average well color development (AWCD) of all carbon sources and the functional diversity based on the Shannon index decreased (P<0.05)in the following order:wasteland>forest>tea garden.For the DGGE analysis,the genetic diversity based on the Shannon index was significantly lower in the tea garden soils than in the wasteland.However,compared to the 90-year-old forest,the tea garden soils showed significantly higher genetic diversity.PLFA analysis showed that the ratio of Gram positive bacteria to Gram negative bacteria was significantly higher in the tea garden soils than in the wasteland,and the highest value was found in the 90-year-old forest.Both the fungal PLFA and the ratio of fungi to bacteria were significantly higher in the three tea garden soils than in the wasteland and forest,indicating that fungal PLFA was significantly affected by land-use change.Based on cluster analysis of the soil microbial community structure,all three analytical methods showed that land-use change had a greater effect on soil microbial community structure than tea garden age.

  3. The cost-effectiveness of rotavirus vaccination: Comparative analyses for five European countries and transferability in Europe.

    Science.gov (United States)

    Jit, Mark; Bilcke, Joke; Mangen, Marie-Josée J; Salo, Heini; Melliez, Hugues; Edmunds, W John; Yazdan, Yazdanpanah; Beutels, Philippe

    2009-10-19

    Cost-effectiveness analyses are usually not directly comparable between countries because of differences in analytical and modelling assumptions. We investigated the cost-effectiveness of rotavirus vaccination in five European Union countries (Belgium, England and Wales, Finland, France and the Netherlands) using a single model, burden of disease estimates supplied by national public health agencies and a subset of common assumptions. Under base case assumptions (vaccination with Rotarix, 3% discount rate, health care provider perspective, no herd immunity and quality of life of one caregiver affected by a rotavirus episode) and a cost-effectiveness threshold of euro30,000, vaccination is likely to be cost effective in Finland only. However, single changes to assumptions may make it cost effective in Belgium and the Netherlands. The estimated threshold price per dose for Rotarix (excluding administration costs) to be cost effective was euro41 in Belgium, euro28 in England and Wales, euro51 in Finland, euro36 in France and euro46 in the Netherlands.

  4. Contribution to the activation analysis of the rare gases. Contribution to the analysis of carbon monoxide and water vapour in gases (1963); Contribution a l'analyse par activation des gaz rares. Contribution a l'analyse de l'oxyde de carbone et de la vapeur d'eau dans les gaz (1963)

    Energy Technology Data Exchange (ETDEWEB)

    Diebolt, J [Commisariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1963-07-15

    In the present work, we have applied radioactive analysis to the general technique of rare gas separation. This separation is carried out on active charcoal, at constant pressure. The desorption of the gas is caused by an increase in the initial temperature of adsorption. These separations are quantitative and can be confirmed by chemical analysis. The volumes of desorbed gas are measured by radioactive counting. We have also used radioactivation to study the reduction of palladous chloride by carbon monoxide. Since this reduction is quantitative, we can have a knowledge of the mass of palladium reduced by measuring its activity. We have used the property which have organic chlorides of being hydrolysed by water vapour and of liberating hydrochloric acid to study quantitatively the amount of water vapour which a gas contains. The hydrochloric acid formed is measured by activation of the chlorine in the acid. (author) [French] Dans les travaux que nous presentons, nous avons applique l'analyse par radioactivation, a la technique generale de separation des gaz rares. Cette separation est faite sur charbon active, a pression constante. La desorption des gaz est provoquee par une augmentation de la temperature initiale d'adsorption. Ces separations sont quantitatives, et peuvent etre exploitees par l'analyse chimique. Les volumes de gaz dedorbes sont mesures par comptage de la radioactivite. Nous avons egalement utilise la radioactivation pour l'etude de la reduction du chlorure palladeux par l'oxyde de carbone. Cette reduction etant quantitative, nous pouvons connaitre la masse de palladium reduit par la mesure de son activite. Nous avons exploite la propriete que possede un chlorure organique d'etre hydrolise par la vapeur d'eau et de liberer de l'acide chlorhydrique pour etudier quantitativement la vapeur d'eau contenue dans un gaz. L'acide chlorhydrique forme est mesure par l'activation du chlore de l'acide. (auteur)

  5. Working regime identification for natural circulation loops by comparative thermalhydraulic analyses with three fluids under identical operating conditions

    International Nuclear Information System (INIS)

    Sarkar, Milan K.S.; Basu, Dipankar N.

    2015-01-01

    Highlights: • Thermalhydraulic analyses of NCL to justify the use of supercritical condition. • Mass flow rate of supercritical loop increases with heater power till a maxima. • Supercritical loop suffer from HTD beyond the maxima with jump in fluid temperature. • HTD is pronounced at higher sink temperatures and pressures just above critical. • Supercritical CO_2 is preferred fluid till the HTD and single-phase water afterwards. - Abstract: Computational investigation for comparative thermalhydraulic analyses of rectangular natural circulation loops is performed to propose a guideline for selecting the working fluid and nature of the loop, subcritical or supercritical, under identical levels of operating parameters like pressure, heating power and coolant temperature. A 3-d uniform-diameter loop geometry is developed with horizontal heating and cooling. Heating is provided in constant heat flux mode, whereas cooling is through a constant temperature sink. Due to favourable thermophysical properties and environmental conformity, water, CO_2 and R134a are selected as possible working fluids. Operational parameters are set so as to have sub- to supercritical condition for CO_2, supercritical for R134a and single-phase liquid for water. Mass flow rate for supercritical fluid rapidly increases with heater power, when the fluid is allowed to cross the pseudocritical point during its passage through the heater, and exhibits a maxima. Drastic fall in mass flow rate can be observed beyond the maxima, accompanied by a jump in maximum fluid temperature and a rapid decline in sink-side heat transfer coefficient. That can be identified as heat transfer deterioration in supercritical natural circulation loops, a highly undesirable situation from loop safety point of view. Allowable working range of heater power can be enhanced by increasing system pressure and decreasing sink temperature. For any specified set of operating conditions, CO_2-based supercritical loops

  6. Working regime identification for natural circulation loops by comparative thermalhydraulic analyses with three fluids under identical operating conditions

    Energy Technology Data Exchange (ETDEWEB)

    Sarkar, Milan K.S.; Basu, Dipankar N., E-mail: dipankar.n.basu@gmail.com

    2015-11-15

    Highlights: • Thermalhydraulic analyses of NCL to justify the use of supercritical condition. • Mass flow rate of supercritical loop increases with heater power till a maxima. • Supercritical loop suffer from HTD beyond the maxima with jump in fluid temperature. • HTD is pronounced at higher sink temperatures and pressures just above critical. • Supercritical CO{sub 2} is preferred fluid till the HTD and single-phase water afterwards. - Abstract: Computational investigation for comparative thermalhydraulic analyses of rectangular natural circulation loops is performed to propose a guideline for selecting the working fluid and nature of the loop, subcritical or supercritical, under identical levels of operating parameters like pressure, heating power and coolant temperature. A 3-d uniform-diameter loop geometry is developed with horizontal heating and cooling. Heating is provided in constant heat flux mode, whereas cooling is through a constant temperature sink. Due to favourable thermophysical properties and environmental conformity, water, CO{sub 2} and R134a are selected as possible working fluids. Operational parameters are set so as to have sub- to supercritical condition for CO{sub 2}, supercritical for R134a and single-phase liquid for water. Mass flow rate for supercritical fluid rapidly increases with heater power, when the fluid is allowed to cross the pseudocritical point during its passage through the heater, and exhibits a maxima. Drastic fall in mass flow rate can be observed beyond the maxima, accompanied by a jump in maximum fluid temperature and a rapid decline in sink-side heat transfer coefficient. That can be identified as heat transfer deterioration in supercritical natural circulation loops, a highly undesirable situation from loop safety point of view. Allowable working range of heater power can be enhanced by increasing system pressure and decreasing sink temperature. For any specified set of operating conditions, CO{sub 2}-based

  7. Télédétection et cartographie à petite échelle des paysages de la France de l’Ouest

    Directory of Open Access Journals (Sweden)

    Vincent DUBREUIL

    1993-06-01

    Full Text Available Les images des satellites NOAAAVHRR sont utilisées dans le but d’établir une cartographie détaillée des paysages ruraux dans la France de l’Ouest. Douze images de 1985 à 1990 représentant l’indice de végétation NDVI ont été sélectionnées. Une analyse discriminante pas à pas permet de classer les pixels de l’image en fonction de 16 échantillons choisis comme représentatifs des types de paysages et des régions agricoles de l’Ouest. Les limites des classes ainsi obtenues sont fort comparables aux cartes communales thématiques d’utilisation du sol des atlas régionaux.

  8. Methodology and optimization in the design and analysis of the efficiency of incompressible fluid turbomachines; Methodologie et optimisation dans la conception et l'analyse des performances des turbomachines a fluide incompressible

    Energy Technology Data Exchange (ETDEWEB)

    Asuaje, M.

    2003-07-15

    Faced with the problem of design in the pump industry, the main difficulty of manufacturers is to have fast, reliable and accurate methods. This research work involving, both theory and experiments deals, with this topic. We have developed a complete procedure for design, performance analysis and optimization of centrifugal and mixed incompressible flow turbomachinery. First of all, the definition of the pump geometry as well as the analysis of its global performance are carried out starting from the mean streamline method (1D), based on both ideal models and experimental correlations. A second stage of optimization is achieved from a quasi 3D method, by studying the meridional flow and blade to blade flow, using REMIX software developed by LEMFI. Finally, a three-dimensional flow study is performed by CFD tools from AEA-Technology group (CFX). The three-dimensional study provides the means to complete and validate the established procedure. To illustrate this procedure, a centrifugal machine with a volute was studied used. First, the analysis of the existing impeller was carried out to develop the various steps of the procedure. Then, the whole impeller-volute pump, was studied and compared with the previous trial runs. Special attention was paid to unsteady effects, resulting from impeller volute interaction. The results obtained are satisfactory. Finally, the integral method was applied to optimize a mixed flow pump equipped with a de-swirl. As it is a badly dimensioned pump, it is a good example of what this method can do. (author)

  9. Comparative Studies of Chemical Effects following Nuclear Reactions and Transformations on Metal Organic Phenyl Compounds; Etudes Comparatives des Effets Chimiques Induits par les Reactions et les Transformations Nucleaires sur des Composes Phenylmetalliques; 0421 0420 0410 0414 ; Estudios Comparativos de los Efectos Quimicos de las Reacciones y Transformaciones Nucleares en Compuestos Fenil-Organometalicos

    Energy Technology Data Exchange (ETDEWEB)

    Merz, E.; Riedel, H. J. [Kernforschungsanlage, Juelich, Federal Republic of Germany (Germany)

    1965-04-15

    molecule by the nuclear recoil and the resulting excitation. The hypothesis is put forward that the kind and quantity of certain new radioactive species produced in connection with nuclear events is less a function of the nature and concentration of primary recoil fragments than are the ions, radicals and lattice defects imparted to the irradiated materials by secondary recoil effects (elastic and inelastic interactions) , including the peculiar influence of oxygen. (author) [French] Les auteurs ont etudie les effets chimiques provoques par les atomes chaud de recul resultant des reactions nucleaires dans les solides et dans les liquides en se fondant sur une vaste comparaison des produits des processus (n,{gamma}) et (n,2n) dans les composes phenyles du germanium, de l'etain, du plomb, de l'arsenic et de l'antimoine. En outre, ils ont compare les produits de recul radioactifs formes apres capture K dans le tetraphenyl- germanium-{sup 68}Ge avec les resultats du processus (n,{gamma}) dans le triphenylgalliumet du processus (n,p) sur le tetraphenylgermanium. Enfin, ils ont etudie la transition {beta}{sup -} dans laquelle {sup 77}Ge est remplace par {sup 77}As dans le compose. En appliquant differentes methodes de separation, par exemple la chromatographie d'adsorption sur alumine, l'echange d'ions et l'electrophorese, ils ont separe les divers produits de recul radioactifs et determine les rendements individuels. Ils ont constate que, dans les reactions nucleaires, les composes des metaux cites ayant des coordinats identiques forment pratiquement les memes classes.de produits de recul. Toutefois, pour la distribution des rendements, il y a des differences caracteristiques entre la reaction (n,{gamma}) et la reaction (n,2n). L'influence sur les rendements est a peine perceptible lorsque les irradiations ont lieu dans des liquides ou des solutions. Mais les differences trouvees pour les nouveaux composes formes par des transformations nucleaires sont frappantes, en ce qui

  10. Work/Family Balancing and 24/7 Work Schedules: Network Analysis of Strategies in a Transport Company Cleaning Service: Concilier travail-famille et horaires 24/7: analyse réseau des stratégies au sein du service de nettoyage d'une compagnie de transport.

    Science.gov (United States)

    Lefrançois, Mélanie; Saint-Charles, Johanne; Riel, Jessica

    2017-11-01

    Whether or not official work/family balance measures exist within an organization, scheduling accommodations often go through informal channels involving colleagues and superiors and are negotiated within interpersonal relationships. This study examines the relationship dimensions of the scheduling strategies of cleaners working atypical hours in the transport sector through the lenses of ergonomic activity, network, and gender analyses. Using semi-directed interviews, observation, and network analysis, we revealed the effect of gender on relationship dynamics and the influence of these dynamics on work/family balance strategies deployed by cleaners. One of the main contributions of this study is to demonstrate the decisive effect of relationships by revealing inequalities in access to organizational social networks. Creating spaces to discuss work/family balancing and a more equitable circulation of information could contribute to reducing inequalities associated with gender, social status, and family responsibilities and support the work/family strategies developed by workers dealing with restrictive work schedules. Résumé Les accommodements du temps de travail pour la conciliation travail-famille (CTF) passent souvent par des ententes informelles qui s'inscrivent dans les relations entre collègues ou avec des gestionnaires. Notre étude, intégrant l'ergonomie et la communication dans une perspective de genre, porte sur les dimensions relationnelles des stratégies de choix d'horaire d'agentes et agents de nettoyage devant composer avec des horaires atypiques dans le secteur des transports. À partir d'entretiens semi-dirigés, d'observations et d'analyse de réseaux, nous avons pu observer l'influence des dynamiques relationnelles, notamment de genre, sur les stratégies de CTF. Un apport central de cette étude est de montrer l'effet structurant des relations en révélant notamment des inégalités dans l'accès aux ressources facilitant le choix d

  11. Water and beverage consumption among children aged 4?13 years in France: analyses of INCA 2 (?tude Individuelle Nationale des Consommations Alimentaires 2006?2007) data

    OpenAIRE

    Vieux, Florent; Maillot, Matthieu; Constant, Florence; Drewnowski, Adam

    2016-01-01

    Objective To examine the consumption of plain water among children in France and compare total water intakes with guidelines issued by the European Food Safety Authority (EFSA). Design Nationally representative data were used to assess food, beverage and water consumption by sex, age group (4?8 years, 9?13 years), income-to-poverty ratio, eating occasion and location. Beverages were classified into nine groups: water (tap or bottled), milk, 100 % fruit juice, sodas, fruit drinks, hot beverage...

  12. Non-destructive analysis of major components in plant materials by mean of 14-MeV neutrons; Analyse ''non destructrice'' des principaux constituants de la matiere vegetale apres irradiation aux neutrons de 14 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Garrec, J P [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1968-07-01

    (n,p) , (n,{alpha}) et (n,2n). Les recherches actuelles portent sur l'exploitation complete du spectre gamma de matiere vegetale activee. Le spectre est decompose en 7 spectres principaux suivant La methode des moindres carres, par une calculatrice. En premiere approximation, ce sont ceux que donnent des etalons d'aluminium, de calcium, de potassium, de magnesium, de phosphore, de silicium et de chlore, dans des conditions standard d'activation et de decroissance radioactive. L'avantage recherche par ce moyen d'analyse n'est pas l'extreme sensibilite, mais la rapidite et, par cela, il est particulierement bien adapte aux dosages rapides et simultanes d'elements interessant l'agronomie. (auteur)

  13. Les mécanismes des réductions budgétaires et leurs conséquences sur la diffusion de la langue française : Analyse de la situation en 2013

    Directory of Open Access Journals (Sweden)

    Frédéric Mazières

    2013-12-01

    Full Text Available Considérer la diplomatie linguistique sans se référer aux crédits qui l’alimentent peut entraîner des erreurs d’appréciation. On évoque souvent les budgets linguistiques sans vraiment connaître leurs modalités de fonctionnement. La qualité et l’efficacité de la diffusion de la langue française dépendent des paramètres didactiques, soit, mais aussi des paramètres budgétaires. Nous retrouvons un des axes « méta-didactiques » de la diffusion linguistique. Cet article est, au moins, l’occasion d’une explication des modalités budgétaires de la diffusion linguistique.

  14. Comparative proteomics analyses of Kobresia pygmaea adaptation to environment along an elevational gradient on the central Tibetan Plateau.

    Directory of Open Access Journals (Sweden)

    Xiong Li

    Full Text Available Variations in elevation limit the growth and distribution of alpine plants because multiple environmental stresses impact plant growth, including sharp temperature shifts, strong ultraviolet radiation exposure, low oxygen content, etc. Alpine plants have developed special strategies to help survive the harsh environments of high mountains, but the internal mechanisms remain undefined. Kobresia pygmaea, the dominant species of alpine meadows, is widely distributed in the Southeastern Tibet Plateau, Tibet Autonomous Region, China. In this study, we mainly used comparative proteomics analyses to investigate the dynamic protein patterns for K. pygmaea located at four different elevations (4600, 4800, 4950 and 5100 m. A total of 58 differentially expressed proteins were successfully detected and functionally characterized. The proteins were divided into various functional categories, including material and energy metabolism, protein synthesis and degradation, redox process, defense response, photosynthesis, and protein kinase. Our study confirmed that increasing levels of antioxidant and heat shock proteins and the accumulation of primary metabolites, such as proline and abscisic acid, conferred K. pygmaea with tolerance to the alpine environment. In addition, the various methods K. pygmaea used to regulate material and energy metabolism played important roles in the development of tolerance to environmental stress. Our results also showed that the way in which K. pygmaea mediated stomatal characteristics and photosynthetic pigments constitutes an enhanced adaptation to alpine environmental stress. According to these findings, we concluded that K. pygmaea adapted to the high-elevation environment on the Tibetan Plateau by aggressively accumulating abiotic stress-related metabolites and proteins and by the various life events mediated by proteins. Based on the species'lexible physiological and biochemical processes, we surmised that environment change

  15. Construction and comparative analyses of highly dense linkage maps of two sweet cherry intra-specific progenies of commercial cultivars.

    Directory of Open Access Journals (Sweden)

    Carolina Klagges

    Full Text Available Despite the agronomical importance and high synteny with other Prunus species, breeding improvements for cherry have been slow compared to other temperate fruits, such as apple or peach. However, the recent release of the peach genome v1.0 by the International Peach Genome Initiative and the sequencing of cherry accessions to identify Single Nucleotide Polymorphisms (SNPs provide an excellent basis for the advancement of cherry genetic and genomic studies. The availability of dense genetic linkage maps in phenotyped segregating progenies would be a valuable tool for breeders and geneticists. Using two sweet cherry (Prunus avium L. intra-specific progenies derived from crosses between 'Black Tartarian' × 'Kordia' (BT×K and 'Regina' × 'Lapins'(R×L, high-density genetic maps of the four parental lines and the two segregating populations were constructed. For BT×K and R×L, 89 and 121 F(1 plants were used for linkage mapping, respectively. A total of 5,696 SNP markers were tested in each progeny. As a result of these analyses, 723 and 687 markers were mapped into eight linkage groups (LGs in BT×K and R×L, respectively. The resulting maps spanned 752.9 and 639.9 cM with an average distance of 1.1 and 0.9 cM between adjacent markers in BT×K and R×L, respectively. The maps displayed high synteny and co-linearity between each other, with the Prunus bin map, and with the peach genome v1.0 for all eight LGs (LG1-LG8. These maps provide a useful tool for investigating traits of interest in sweet cherry and represent a qualitative advance in the understanding of the cherry genome and its synteny with other members of the Rosaceae family.

  16. Self-sampling with HPV mRNA analyses from vagina and urine compared with cervical samples.

    Science.gov (United States)

    Asciutto, Katrin Christine; Ernstson, Avalon; Forslund, Ola; Borgfeldt, Christer

    2018-04-01

    In order to increase coverage in the organized cervical screening program, self-sampling with HPV analyses has been suggested. The aim was to compare human papillomavirus (HPV) mRNA detection in vaginal and urine self-collected samples with clinician-taken cervical samples and the corresponding clinician-taken histological specimens. Self-collected vaginal, urine and clinician-taken cervical samples were analyzed from 209 women with the Aptima mRNA assay (Hologic Inc, MA, USA). Cervical cytology, colposcopy, biopsy and/or the loop electrosurgical excision procedure (LEEP) were performed in every examination. The sensitivity of the HPV mRNA test in detecting high-grade squamous intraepithelial lesions (HSIL)/adenocarcinoma in situ (AIS)/cancer cases was as follows: for the vaginal self-samples 85.5% (95% CI; 75.0-92.8), the urinary samples 44.8% (95% CI; 32.6-57.4), and for routine cytology 81.7% (95% CI; 70.7-89.9). For the clinician-taken cervical HPV samples the sensitivity of the HPV mRNA test in detecting HSIL/AIS/cancer was 100.0% (95% CI; 94.9-100.0). The specificity of the HPV mRNA was similar for the clinician-taken cervical HPV samples and the self-samples: 49.0% vs. 48.1%. The urinary HPV samples had a specificity of 61.9% and cytology had a specificity of 93.3%. The sensitivity of the Aptima HPV mRNA test in detecting HSIL/AIS/cancer from vaginal self-samples was similar to that of routine cytology. The Aptima HPV mRNA vaginal self-sampling analysis may serve as a complement in screening programs. Copyright © 2018 Elsevier B.V. All rights reserved.

  17. Comparative Proteomics Analyses of Kobresia pygmaea Adaptation to Environment along an Elevational Gradient on the Central Tibetan Plateau

    Science.gov (United States)

    Li, Xiong; Yang, Yunqiang; Ma, Lan; Sun, Xudong; Yang, Shihai; Kong, Xiangxiang; Hu, Xiangyang; Yang, Yongping

    2014-01-01

    Variations in elevation limit the growth and distribution of alpine plants because multiple environmental stresses impact plant growth, including sharp temperature shifts, strong ultraviolet radiation exposure, low oxygen content, etc. Alpine plants have developed special strategies to help survive the harsh environments of high mountains, but the internal mechanisms remain undefined. Kobresia pygmaea, the dominant species of alpine meadows, is widely distributed in the Southeastern Tibet Plateau, Tibet Autonomous Region, China. In this study, we mainly used comparative proteomics analyses to investigate the dynamic protein patterns for K. pygmaea located at four different elevations (4600, 4800, 4950 and 5100 m). A total of 58 differentially expressed proteins were successfully detected and functionally characterized. The proteins were divided into various functional categories, including material and energy metabolism, protein synthesis and degradation, redox process, defense response, photosynthesis, and protein kinase. Our study confirmed that increasing levels of antioxidant and heat shock proteins and the accumulation of primary metabolites, such as proline and abscisic acid, conferred K. pygmaea with tolerance to the alpine environment. In addition, the various methods K. pygmaea used to regulate material and energy metabolism played important roles in the development of tolerance to environmental stress. Our results also showed that the way in which K. pygmaea mediated stomatal characteristics and photosynthetic pigments constitutes an enhanced adaptation to alpine environmental stress. According to these findings, we concluded that K. pygmaea adapted to the high-elevation environment on the Tibetan Plateau by aggressively accumulating abiotic stress-related metabolites and proteins and by the various life events mediated by proteins. Based on the species'lexible physiological and biochemical processes, we surmised that environment change has only a slight

  18. Comparative phenotypic and genotypic analyses of Salmonella Rissen that originated from food animals in Thailand and United States.

    Science.gov (United States)

    Pornsukarom, S; Patchanee, P; Erdman, M; Cray, P F; Wittum, T; Lee, J; Gebreyes, W A

    2015-03-01

    Salmonella enterica serovar Rissen has been recognized as one of the most common serovar among humans and pork production systems in different parts of the world, especially Asia. In the United States, this serovar caused outbreaks but its epidemiologic significance remains unknown. The objectives of this study were to compare the phenotypic (antimicrobial susceptibility) and genotypic attributes of Salmonella Rissen isolated in Thailand (Thai) and the United States (US). All the Thai isolates (n = 30) were recovered from swine faecal samples. The US isolates (n = 35) were recovered from swine faecal samples (n = 29), cattle (n = 2), chicken (n = 2), dog (n = 1) and a ready-to-eat product (n = 1). The antimicrobial susceptibility of isolates was determined using the Kirby-Bauer disk diffusion method with a panel of 12 antimicrobials. Pulse-field gel electrophoresis (PFGE) was used to determine the genotypic diversity of isolates. All Thai isolates showed multidrug resistance (MDR) with the most frequent antibiotic resistance shown against ampicillin (100%), sulfisoxazole (96.7%), tetracycline (93.3%), streptomycin (90%) and chloramphenicol (30%). About half of the isolates of USA origin were pan-susceptible and roughly 30% were resistant to only tetracycline (R-type: Te). Salmonella Rissen isolated from Thailand and the USA in this study were found to be clonally unrelated. Genotypic analyses indicated that isolates were clustered primarily based on the geographic origin implying the limited clonality among the strains. Clonal relatedness among different host species within the same geography (USA) was found. We found genotypic similarity in Thai and US isolates in few instances but with no epidemiological link. Further studies to assess propensity for increased inter-regional transmission and dissemination is warranted. © 2014 Blackwell Verlag GmbH.

  19. Bilan et apports de différentes Analyses Sociales du Cycle de Vie menées dans le secteur des agro-industries

    Directory of Open Access Journals (Sweden)

    Delcour, A.

    2015-01-01

    Full Text Available Assessment and contributions of different Social Life Cycle Assessments performed in the agribusiness sector. Introduction. Consumers are attaching increasing importance to the sustainability of the products they purchase. The agribusiness sector is well aware of this trend and is making efforts to guarantee product sustainability. Literature. Social Life Cycle Assessment (S-LCA is a widely used methodology (like others in this field, such as ISO 26000 and SA 8000 for evaluating the social impact of the activities involved in the life cycle of a product. The S-LCA guidelines were published in 2009 and therefore the framework for this methodology is not yet well established. Nevertheless, some S-LCA studies have been completed and have contributed to the development of the methodology. The objective of this paper is to give feedback to the agribusiness sector and researchers regarding prospects for future use of Social Life Cycle Assessment in the agribusiness sector. Papers selected for this literature review have been chosen on the basis of Scopus's query from 2000 to the present day. Scopus's query contains analyses of major international conferences. The case studies in the agribusiness sector that are reviewed in this paper highlight the usefulness of a social hotspots database, the need for stakeholder involvement in S-LCA implementation, the link between S-LCA and its regional context, and the benefits of developing causal links between indicators and impact categories, such as working conditions and governance. Conclusions. Further methodological investigation needs to be conducted in order to standardize this new methodology. Its ability to provide an overview of assessment of socioeconomic impacts makes it a good choice for evaluating the aspect of social impact as part of sustainability studies.

  20. La syntaxe comparative des connecteurs argumentatifs – l’exemple du couple français-tchèque

    Directory of Open Access Journals (Sweden)

    Ondřej Pešek

    2010-01-01

    Full Text Available The paper deals with the syntactic features of textual connectives in the contemporary French and Czech language. The study is a comparative one. The argumentative connectives are lexical units that participate on the text structuration and mark the argumentative orientation of the constituents they connect. Being defined on the basis of textual criteria, the units we include to the category issue from different morphosyntactic classes – conjunctions of subordination, conjunctions of coordination, adverbials. Although these classes present in French and in Czech some different distributional features, their accumulation in one clause is ruled by the same principles that operate on the level of the logical form.

  1. Morphometric analysis of the temporomandibular joint with MRI in 320 joints; Morphometrische Analyse des Kiefergelenkes anhand von 320 Gelenken mit der MRT

    Energy Technology Data Exchange (ETDEWEB)

    Lemke, A.J.; Felix, R. [Charite, Univ. Berlin, Campus Virchow-Klinikum, Klinik fuer Strahlenheilkunde (Germany); Griethe, M.; Peroz, I.; Lange, K.P. [Charite, Univ. Berlin, Campus Virchow-Klinikum, Zentrum fuer Zahnmedizin, Abt. fuer zahnaerztliche Prothetik und Alterszahnmedizin (Germany)

    2005-02-01

    Purpose: to compare several morphometric parameters in MRI with the functional status of the articular disc in a large patient group suffering from internal derangement (ID) of the temporomandibular joint (TMJ). Materials and methods: in a retrospective study, 320 analyzable high resolution MRI examinations of the TMJs obtained in a 1.5 T unit were evaluated in 184 patients with clinically suspected ID. The analysis included the anatomical structures and a number of morphometric parameters previously described in the literature. The parameters were compared with the position of the articular disc. Results: the disc position was categorized as ''normal'' (NDP, 21.9%, n = 70), ''anterior displacement with reduction on opening'' (AMR, 51.6%, n = 165) and ''anterior displacement without reduction on opening'' (AOR, 26.6%, n = 85). With increasing disc displacement, significant configurational changes of the disc were observed. Disc displacement was associated with changes of the condyle consisting of increasing deformity and other degenerative changes. A large tuberculum and marked inclination of the eminence can be seen as predisposition for the development of ID. With increasing severity of the ID, the position of the condyle moved from a centric position of the condylar center to an excentric (dorsal and cranial) position. Conclusion: MRI demonstrated that increasing disc displacement is associated with changes of the disc, condyles and condylar position in the fossa. (orig.)

  2. Uncertainty Analysis of a Fractured Reservoir’s Performance: A Case Study Analyse d’incertitudes des performances d’un réservoir fracturé : étude de cas

    Directory of Open Access Journals (Sweden)

    Khosravi M.

    2012-05-01

    Full Text Available In recent years, the oil industry has given great importance to reservoir management and reservoir uncertainty analysis. The development of a method that can model and quantify uncertainties in reservoir simulation studies in an efficient and practical way is clearly desirable. Different approaches such as Response Surface Methodology (RSM and Monte-Carlo simulation have been used to address the uncertainties. In this paper, response surface method is used to realize the most influential parameters on pressure drop and recovery factor changes, regarding their practical levels of uncertainties during the development of fractured reservoir model. The present approach is performed to magnify the significant parameters and developing compatible and more realistic proxy equation for forecasting oil recovery from a typical low permeable fractured reservoir. The proxy model allows Monte-Carlo analysis to determine sensitivities and the quantification of the impact of uncertainty on production forecasts. Results indicate that the oil recovery is more sensitive to aquifer strength, fracture permeability and block height. In addition, however the interaction between other parameters, such as matrix size, fracture permeability and aquifer volume, showed a degree of importance during this analysis. Monte-Carlo analysis forecasts wide range of oil recovery for this field development. Ces dernières années, l’industrie du pétrole a accordé une grande importance à la gestion et à l’analyse d’incertitudes des réservoirs. Le développement d’une méthode permettant de modéliser et de quantifier les incertitudes au cours des études de simulation de réservoir d’une façon efficace et pratique est clairement souhaitable. Des approches différentes telles que la méthodologie des surfaces de réponse (RSM; Response Surface Methodology et la simulation de Monte-Carlo ont été utilisées pour évaluer les incertitudes. Au sein de cet article, la m

  3. Des racines et des ailes

    Directory of Open Access Journals (Sweden)

    Stéphanie Vincent-Geslin

    2012-05-01

    Full Text Available Les mobilités pendulaires semblent être en augmentation en Europe depuis une dizaine d’années. Cette croissance du temps passé à se déplacer amène à remettre en question la conjecture de Zahavi et apparaît relativement inexplicable en regard du paradigme classique de l’acteur rationnel traditionnellement utilisé dans le champ des transports. Si, dans la littérature, les temps de déplacements sont principalement expliqués par le contexte résidentiel, la forme urbaine et le travail, ce cadre explicatif ne dit rien des processus de décision eux-mêmes qui amènent aux pendularités intensives.À partir d’une enquête qualitative menée auprès de pendulaires français, suisses et belges, cette contribution propose d’analyser les arbitrages et les éléments déterminants des processus de la grande pendularité. Les mobilités quotidiennes pendulaires apparaissent comme le résultat de compromis entre activité professionnelle, attachement résidentiel et choix de vie et prennent ainsi la forme de stratégies de conciliation entre vie privée et vie professionnelle. Ces mobilités spatiales permettent alors paradoxalement la préservation des ancrages résidentiels, sociaux et familiaux.Roots and wings. Long-distance commuting patterns, or how to conciliate professional and personal lifeLong-distance commuting patterns appear to be increasing in Europe over the last ten years. These raising mobility patterns lead to reappraise the Zahavi conjecture and appear largely inexplicable by the classical rational actor paradigm traditionally used in transportation research. In literature, commuting is mainly explained by residential contexts, urban forms and job. Nevertheless this theoretical frame says little about the decision-making processes themselves. Based on a qualitative survey conducted in three European countries - France, Belgium and Switzerland – among a population of high commuters, this paper proposes an analysis of

  4. Le «blues de la canne et du coton» : étude comparative des fonctions socioculturelles du gwo-ka et du blues The “blues of the cane and cotton”: a comparative study of social and cultural functions of the gwo-ka and the blues

    Directory of Open Access Journals (Sweden)

    Steve Gadet

    2012-05-01

    Full Text Available L’article s’intéresse à l’interculturalité entre deux phénomènes culturels que sont le Gwo-ka et le Blues issus de la diaspora africaine aux Amériques. Le Gwo-ka est une expression culturelle née en Guadeloupe, île française située dans la mer des Caraïbes. Le Blues est également une expression culturelle née dans le Sud des États-Unis. À partir de l’analyse de leur « matrice » sociohistorique, il s’agira de mettre en évidence les rapprochements entre les différentes fonctions socioculturelles. Nous tenterons de comprendre si la théorie de l’Atlantique Noir de Paul Gilroy, reliant les communautés afro-diasporiques du Nouveau Monde, est valable dans le cadre de notre sujet d’étude.The article deals with the intercultural exchanges between two cultural movements rooted in the African Diasporas. In Guadeloupe, a French island in the Caribbean, Gwo-ka was born on the plantation in the 17th century. Blues appeared in the southern United-States by the end of the 19th century. In order to illustrate the similarities between these two afro-diasporic cultural phenomena, the article first examines the economic and social factors that prompted their emergence. Second, it compares their socio-cultural functions within their respective communities. Using Paul Gilroy’s theory of the Black Atlantic, the article concludes with a questioning of his thesis within the framework of the present study.

  5. Le statut politique des petits territoires insulaires à vocation touristique a-t’il une influence sur leur performance économique et sociale ? Approche comparative Does political status of small island tourist economies have an influence on their economic and social performance ? Comparative approach

    Directory of Open Access Journals (Sweden)

    Louis Dupont

    2012-05-01

    Full Text Available Le paradigme du développement dans les Petites Economies Insulaires se définit par divers facteurs. Parmi ces derniers figurent entre-autres, le statut politique et le niveau de développement touristique atteint par ces territoires. Cette étude, en croisant diverses analyses a pour but d’évaluer et de comparer empiriquement à l’aide de vingt-cinq indicateurs socio-économiques et démographiques, l’influence de différentes variables et plus particulièrement de celle relative au statut politique sur la performance économique et sociale de deux groupes de territoires, l’un composé de seize petits espaces insulaires de la Caraïbe et du Pacifique, politiquement dépendants et l’autre, de dix-neuf îles des mêmes régions qui ont accédé à la souveraineté. D’une part, les résultats montrent que : comme variable explicative, le statut politique associé à d’autres facteurs intervient pour les deux-tiers dans la performance économique et sociale de ces îles. D’autre part, ils indiquent que les territoires insulaires politiquement dépendants sont économiquement plus prospères, socialement plus avancés, et démographiquement d’une plus grande maturité que ceux ayant acquis leur souveraineté. Toutefois, ces résultats ne doivent en aucun cas être interprétés comme des arguments contre la décolonisation, qui demeure une démarche moralement et universellement soutenable. Enfin, ils montrent également que les îles dépendantes qui bénéficient d’une large autonomie politique affichent en moyenne des résultats économiques et sociaux bien meilleurs que celles qui restent politiquement et centralement très liées à leur métropole, cas notamment de la Guadeloupe et de la Martinique pour lesquelles, en guise d’illustration nous proposons dans le cadre de leur probable évolution statutaire, un modèle de gouvernance qui, au plan politique soit le mieux adapté aux caractéristiques socio-économiques et

  6. Qualification des logiciels numériques. Application à un logiciel d'analyse de la combustion dans les moteurs à allumage commandé Qualification of Numerical Software. Application to a Software for Analysing Combustion in Spark-Ignition Engines

    Directory of Open Access Journals (Sweden)

    Vignes J.

    2006-11-01

    Full Text Available La simulation numérique est actuellement très utilisée pour étudier les systèmes physiques. Elle nécessite un programme de calcul scientifique constitué d'un modèle mathématique représentatif du problème étudié et des méthodes numériques de résolution associées. Elle fournit des résultats numériques censés représenter le phénomène physique. Pour pouvoir valider la simulation, il est absolument indispensable, d'une part, d'estimer la propagation des erreurs d'arrondi due à l'arithmétique approchée des ordinateurs et, d'autre part, d'évaluer l'influence des erreurs de données sur les résultats fournis. Nous présentons, dans cet article, le logiciel CADNA qui permet de valider les logiciels numériques. Nous l'appliquons à un logiciel de simulation d'analyse de la combustion dans les moteurs à allumage commandé et en montrons son efficacité. For analyzing physical phenomena, numerical simulation is used more and more frequently. Starting with a mathematical model describing the phenomenon being analyzed, this simulation consists in creating a scientific computing program expressing this model by implementing the numerical methods required for solving it. Simulation is considered to be valid when the results its provides are in agreement with the results issuing from experimenting with the phenomenon. However, to conclude in the possible validity of the simulation, the numerical results provided by the computer must be previously validated. Yet, these results contain a computing error resulting from the propagation of round-off errors caused by the floating-point arithmetic used by the computer. They also contain an error coming from the uncertainties concerning the data of the problem. Hence it is first indispensable to assess the influence of these errors. This article is made up of two parts. The first part concerns the validation of numerical software results. After making a brief review of the floating

  7. Enseignements tirés de la justice transitoire et du rôle des ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... des fonctionnaires, des représentants de la société civile, des chercheurs et des universitaires du Kenya, du Libéria et du Togo. Le rapport de projet sera en outre mis à jour et enrichi grâce une analyse documentaire, des comptes rendus d'atelier et des entrevues de personnes-ressources clés, puis publié sous forme de ...

  8. Comment obtenir des fonds pour la prévention des maladies non ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... une analyse des parties prenantes, une analyse documentaire et des entrevues semi-structurées. Les participants à l'étude proviendront d'organismes gouvernementaux, d'organismes de développement, d'ONG locales et internationales, de groupes professionnels et d'établissements d'enseignement et de recherche.

  9. Regroupement des statistiques sur le secteur des TIC et analyse ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Journal supplement features 10 years of West African health systems research. In the wake of the devastating Ebola virus outbreak in 2014, increased attention has been paid to West Africa's poorly functioning health systems. View moreJournal supplement features 10 years of West African health systems research ...

  10. A comparative study of two approaches to analyse groundwater recharge, travel times and nitrate storage distribution at a regional scale

    Science.gov (United States)

    Turkeltaub, T.; Ascott, M.; Gooddy, D.; Jia, X.; Shao, M.; Binley, A. M.

    2017-12-01

    Understanding deep percolation, travel time processes and nitrate storage in the unsaturated zone at a regional scale is crucial for sustainable management of many groundwater systems. Recently, global hydrological models have been developed to quantify the water balance at such scales and beyond. However, the coarse spatial resolution of the global hydrological models can be a limiting factor when analysing regional processes. This study compares simulations of water flow and nitrate storage based on regional and global scale approaches. The first approach was applied over the Loess Plateau of China (LPC) to investigate the water fluxes and nitrate storage and travel time to the LPC groundwater system. Using raster maps of climate variables, land use data and soil parameters enabled us to determine fluxes by employing Richards' equation and the advection - dispersion equation. These calculations were conducted for each cell on the raster map in a multiple 1-D column approach. In the second approach, vadose zone travel times and nitrate storage were estimated by coupling groundwater recharge (PCR-GLOBWB) and nitrate leaching (IMAGE) models with estimates of water table depth and unsaturated zone porosity. The simulation results of the two methods indicate similar spatial groundwater recharge, nitrate storage and travel time distribution. Intensive recharge rates are located mainly at the south central and south west parts of the aquifer's outcrops. Particularly low recharge rates were simulated in the top central area of the outcrops. However, there are significant discrepancies between the simulated absolute recharge values, which might be related to the coarse scale that is used in the PCR-GLOBWB model, leading to smoothing of the recharge estimations. Both models indicated large nitrate inventories in the south central and south west parts of the aquifer's outcrops and the shortest travel times in the vadose zone are in the south central and east parts of the

  11. Application of wavelet analysis to the nuclear phase space study; Application de l`analyse en ondelettes a l`etude de l`espace des phases nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Jouault, B. [Nantes Univ., 44 (France)

    1996-11-22

    The objective of this thesis is to present a methodology, based on the projection methods used in statistical physics and on the wavelet approach, which allows to obtain various classes of information. A coherent modelling was elaborated as the tools used for generating and solving the evolution equations, expressed in terms of pertinent variables, are based on common concepts. The property of scale separation of the wavelet analysis allows an approximation hierarchy based on the geometrical structure of phase space to be defined. This information structuration offers the opportunity of solving the evolution equations with various degrees of precision by controlling the information loss and avoiding the sampling methods of Monte Carlo type. The application of this methodology to the case of heavy ion collisions needs an entirely numerical treatment of the density matrix evolution equation. This implies a very precise level of description in order to take into account the important dissipation effects occurring in intermediate energy nuclear dynamics. A proper solution less expensive was adopted by using the wavelets analytically expressed, this entailing also the testing of model validity by comparing its results with the analytical solutions. This model takes into account the structure of the system wave functions, thus conserving the microscopical information. The present methodology can be applied also at other energy domains providing the nuclear systems are subject to transient non steady-state regimes. The wavelet analysis was used extensively in the field of signal processing particularly to extract from background a physical signal and also in the field of turbulence phenomena 152 refs.

  12. Eco-efficience et analyse des couts du cycle de vie: Developpement d'un outil d'aide a la conception dans l'industrie aeronautique

    Science.gov (United States)

    Mami, Fares

    The aeronautical sector, responsible for about 3 % of the world emissions of greenhouse gases, predict a 70 % growth in 2025 and 300 % to 500 % in 2050 of its emissions compared to the level of 2005. The decision-makers must thus be supported in their choice of conception to integrate the environmental aspect into the decision-making. Our industrial partner in the aeronautical sector developed an expertise in Life Cycle Assessment (LCA) and seeks to integrate the costs and the environmental impacts in a systematic way into the ecodesign of products. Based on the literature review and the objectives of this research we propose a model of eco-efficiency, which integrates LCA with Life Cycle Costing (LCC). This model is consistent with defined cost cutting and environmental impacts reduction targets and allows a simple interpretation of the results while minimizing the efforts during data collection. The model is applied for 3D printing as an alternative production process in the manufacturing of an aircraft blocker door. 3D printing is a new technology of production working by addition of material and present interesting opportunities of cost cutting and environmental impacts, particularly in the aeronautical domain. The results showed that 3D printing, when associated with improvement in the topology of the part, allows an improvement both on costs and environmental impacts of the part life cycle. Nevertheless, the results are sensitive to the productivity of the 3D printing machine, in particular with costs when the productivity of the 3D printing is reduced. This eco-efficiency model presents several opportunities of improvement. A more elaborate definition of the objectives in reduction of environmental impacts would allow to direct the choices in design to considerations of eco-efficiency at a macro level. Moreover, the integration of the social dimension in the model constitutes an important stage to operationalize the stakes of environmental and social

  13. On groundwater flow modelling in safety analyses of spent fuel disposal. A comparative study with emphasis on boundary conditions

    Energy Technology Data Exchange (ETDEWEB)

    Jussila, P

    1999-11-01

    Modelling groundwater flow is an essential part of the safety assessment of spent fuel disposal because moving groundwater makes a physical connection between a geological repository and the biosphere. Some of the common approaches to model groundwater flow in bedrock are equivalent porous continuum (EC), stochastic continuum and various fracture network concepts. The actual flow system is complex and measuring data are limited. Multiple distinct approaches and models, alternative scenarios as well as calibration and sensitivity analyses are used to give confidence on the results of the calculations. The correctness and orders of magnitude of results of such complex research can be assessed by comparing them to the results of simplified and robust approaches. The first part of this study is a survey of the objects, contents and methods of the groundwater flow modelling performed in the safety assessment of the spent fuel disposal in Finland and Sweden. The most apparent difference of the Swedish studies compared to the Finnish ones is the approach of using more different models, which is enabled by the more resources available in Sweden. The results of more comprehensive approaches provided by international co-operation are very useful to give perspective to the results obtained in Finland. In the second part of this study, the influence of boundary conditions on the flow fields of a simple 2D model is examined. The assumptions and simplifications in this approach include e.g. the following: (1) the EC model is used, in which the 2-dimensional domain is considered a continuum of equivalent properties without fractures present, (2) the calculations are done for stationary fields, without sources or sinks present in the domain and with a constant density of the groundwater, (3) the repository is represented by an isotropic plate, the hydraulic conductivity of which is given fictitious values, (4) the hydraulic conductivity of rock is supposed to have an exponential

  14. Application de la méthode des éléments finis hiérarchiquesà l’analyse thermo- élastique d’unpanneau solaire d’un satellite

    OpenAIRE

    hamzA-CHERIF, Sidi Mohammed

    2013-01-01

    Dans l'ère actuelle, Les satellites sont devenus des outils incontournables dans le développement économique (télécommunications, positionnement, prévision météorologique), militaire (renseignement) et scientifique (observation astronomique, microgravité, observation de la Terre, océanographie, altimétrie). Les satellites en orbite sont soumis à des conditions de fonctionnement très sévères, en plus des effets de l’oxygène atomique, le rayonnement ultraviolet, la radiation é...

  15. L’étude microtopographique et la visualisation 3D dans l’analyse de gravures préhistoriques – L’exemple des pierres gravées de La Marche

    Directory of Open Access Journals (Sweden)

    Nicolas Mélard

    2012-04-01

    Full Text Available L’étude de pierres gravées préhistoriques pose depuis longtemps des problèmes de déchiffrement des motifs et de décodage des traces. La recherche archéologique se sert de plus en plus de moyens d’investigation empruntés des sciences naturelles tels la microscopie et plus récemment le relevé et la visualisation 3D. L’application de la microtopographie a permis d’appréhender de manière plus complète les pierres gravées de La Marche en ajoutant des éléments de compréhension en termes de composition et de construction des motifs (chronologie et morphologie des traits ainsi qu’en termes de technologie (gestes et démarches des graveurs préhistoriques. De plus, il a été possible d’obtenir des informations sur l’histoire des supports avant et après la gravure (choix des matières premières, caractérisation des usures,….The main difficulty in studying the engraved stones of the upper Paléolthic period is the decipherment and the understanding of the various overlapping traces on the surfaces. Scientific research in paleolithic art is trying since more than 20 years to use modern laboritory devises and techniques like the Scanning Electron Microscope and more recently the 3D scanning. For the engraved stones of the site of La Marche have been studied by 3D microtopography as a complementary technique. This non destructif protocole made a new approach of engraving technology and motif composition possible (chronology of the lines, traces morphology etc.. This leads to better understanging of the techniques and gestures used by prehistoric artists. Moreover studies of this type can give more informations obout the function and the history of the stones in a prehistoric rockshelter and by this way the role of theses stones in the life of the magdaleanian hunter-gatherer communities.

  16. Subsidisation of renewable energy; Subventionierung von erneuerbarer Energie. Eine industrieoekonomische Analyse des strategischen Weettbewerbs in der Erneuerbaren-Energieindustrie bei unterschiedlichen staatlichen Regulierungen

    Energy Technology Data Exchange (ETDEWEB)

    Schaller, M.

    2006-07-01

    In the current work we analyze formally selected problems in connection with the subsidisation of renewable energy in finance theoretical and industrial economic models. In the first part of the work we deal with the subsidisation of demonstration projects for testing new technologies in the field of renewable energy. The information about the economical performance of a technology, which is disclosed by first tests, is part of the value of such a demonstration project. We describe this value in a finance theoretical model as a real option. A reason for subsidising a demonstration project is given, when it is not exclusively the investor who benefits from the disclosed information. A technology may prove so efficient in a demonstration project that it will lead to a sustained decrease of the price for renewable energy. In this case the investment in a demonstration project has a positive externality in the form of a so -called consumer-surplus on consumers. This consumer surplus legitimises the subsidisation of demonstration projects. It also may be that other producers of renewable energy profit from a technology that is identical or at least similar to the technology - which is tested in a demonstration project. In this case the producers will benefit from the disclosed information since they can use it to estimate the performance of their own technologies. For this reason the investment in a demonstration project causes here a positive externality in form of an information spill-over to other producers with an identical or at least similar technology, which again legitimises the subsidisation. The second part of the current work contributes to answering the question how a good subsidising system to foster renewable energy should be designed. We therefore compare feed-in tariffs, quota obligations and bidding systems, all three common European subsidising schemes. We investigate which of the systems has the capacity to minimize on the one hand the profits of the

  17. Le mixed price bundling, une stratégie marketing alternative ? Le cas bancaire des « offres jeunes »

    OpenAIRE

    Lambey-Checchin, Christine

    2013-01-01

    International audience; Pratique courante notamment chez les prestataires de service, le mixed price bundling consiste à vendre ensemble des produits ou services complémentaires à un prix spécial. La littérature a montré la supériorité de cette forme de bundling en étudiant ses effets sur les comportements des consommateurs. Le papier l'envisage comme une stratégie marketing et examine ses caractéristiques d'offre et de prix. Les résultats d'une analyse comparative des packages proposés par l...

  18. De l'importance des orbites periodiques: Detection et applications

    Science.gov (United States)

    Doyon, Bernard

    L'ensemble des Orbites Periodiques Instables (OPIs) d'un systeme chaotique est intimement relie a ses proprietes dynamiques. A partir de l'ensemble (en principe infini) d'OPIs cachees dans l'espace des phases, on peut obtenir des quantites dynamiques importantes telles les exposants de Lyapunov, la mesure invariante, l'entropie topologique et la dimension fractale. En chaos quantique (i.e. l'etude de systemes quantiques qui ont un equivalent chaotique dans la limite classique), ces memes OPIs permettent de faire le pont entre le comportement classique et quantique de systemes non-integrables. La localisation de ces cycles fondamentaux est un probleme complexe. Cette these aborde dans un premier temps le probleme de la detection des OPIs dans les systemes chaotiques. Une etude comparative de deux algorithmes recents est presentee. Nous approfondissons ces deux methodes afin de les utiliser sur differents systemes dont des flots continus dissipatifs et conservatifs. Une analyse du taux de convergence des algorithmes est aussi realisee afin de degager les forces et les limites de ces schemes numeriques. Les methodes de detection que nous utilisons reposent sur une transformation particuliere de la dynamique initiale. Cette astuce nous a inspire une methode alternative pour cibler et stabiliser une orbite periodique quelconque dans un systeme chaotique. Le ciblage est en general combine aux methodes de controle pour stabiliser rapidement un cycle donne. En general, il faut connaitre la position et la stabilite du cycle en question. La nouvelle methode de ciblage que nous presentons ne demande pas de connaitre a priori la position et la stabilite des orbites periodiques. Elle pourrait etre un outil complementaire aux methodes de ciblage et de controle actuelles.

  19. Identites et apprentissage des langues Camerounaises | Assob ...

    African Journals Online (AJOL)

    PROMOTING ACCESS TO AFRICAN RESEARCH ... L'étude analyse l'effet des identités multiples sur la motivation des apprenants. ... of multiples identities on learners' motivation and suggests approaches for a rational management ... That is why the study identifies them as key stakeholders whose implication may further ...

  20. La Question de L'impunité des Auteurs de Violations des Droits de L'homme

    Directory of Open Access Journals (Sweden)

    Maria dos Remédios Fontes Silva

    2010-10-01

    Full Text Available Ce travail pretend faire reflechir à propos de la question de l'impunite des autorites de L'Etat face aux violations des droits de l'homme. On abordera cet egard: a le role de I'amnistie ble complicite des autoritesadministratives c la lenteur des procedures judicieuse.     L'analyse de cette question montre qui L'impunite des responsables des violations des droits de l'homme fait peser une menace sur I'ensemble du systeme de protection universelle des droits de l'homme.          On peut on conduire qu 'aucune societe que aspire à la democratie et ala justice ne peut se construire sur I'amoralite des crimes impunis et I'amnesie officielle.

  1. Comparative analyses reveal different consequences of two oxidative stress inducers, gamma irradiation and potassium tellurite, in the extremophile Deinococcus radiodurans

    International Nuclear Information System (INIS)

    Narasimha, Anaganti; Basu, Bhakti; Apte, Shree Kumar

    2014-01-01

    Proteomic and mass spectrometric analyses revealed differential responses of D. radiodurans to two oxidative stressors. While both elicited oxidative stress alleviation response, major divergence was observed at the level of DNA repair, metabolic pathways and protein homeostasis. Response to gamma irradiation was focused on DNA repair and ROS scavenging but supported metabolism as well as protein homeostasis. Tellurite, induced oxidative stress alleviation but decreased reducing affected and adversely affected metabolism and protein homeostasis

  2. Le vernis des apparences

    Directory of Open Access Journals (Sweden)

    Grazia Nicosia

    2010-04-01

    Full Text Available Le but de cet article est de comprendre l’incidence sémiotique du nettoyage d’un tableau ainsi que la résultante cognitive induite sur l’observateur. Cette étude confronte l’analyse des phénomènes visuels engendrés par le jaunissement du vernis et son retrait, à des entretiens réalisés à dessein. Le retrait d’un vernis jauni change considérablement l’image. L’heure, le climat, la saison et l’activité même des personnages s’en trouvent ainsi modifié. La patine peut être perçue, soit comme un obstacle à l’exploration, soit pour ceux qui l’apprécient, comme le medium d’une relation plus intime entre l’œuvre et l’observateur.The purpose of this article is to understand the semiotic impact of the cleaning of a painting and the cognitive effects induced on the observer. This study analyses conjointly the visual phenomenon generated by yellowing varnish and its removal and controlled interviews of observers.The removal of yellowing varnish modifies considerably the perception of the picture. Daytime, climate, season and characters activities are modified. The patina may be perceived either as an obstacle to the painting exploration, or, for those who appreciate it, as a medium for a closer relationship between the painting and the observer.

  3. GENOMIQUE ET LIPIDES Génomique et métabolisme des lipides des plantes

    Directory of Open Access Journals (Sweden)

    Delseny Michel

    2002-03-01

    Full Text Available Il existe dans les bases de données publiques une énorme quantité de séquences d’ADN dérivées de plantes, et notamment la séquence complète du génome d’Arabidopsis thaliana, une plante modèle pour les oléagineux, proche parente du colza. Ces données constituent une ressource importante non seulement pour la compréhension de métabolisme lipidique et de sa régulation, mais aussi pour la sélection et le développement de variétés nouvelles d’oléagineux produisant davantage d’huiles ou des huiles de composition nouvelle. Cette abondance de séquences peut être exploitée, en utilisant les recherches d’homologies, pour identifier les gènes, pour obtenir des informations sur leur fonction, comme pour repérer des gènes candidats codant des fonctions nouvelles. L’analyse de ces bases de données a révélé que la majeure partie des gènes codant des enzymes impliquées dans le métabolisme lipidique appartient à des petites familles multigéniques, reflétant la diversification des fonctions des isoformes. Une analyse du catalogue des ADNc séquencés en aveugle reflète les niveaux d’expression des différents gènes et fournit un aperçu des régulations des flux au travers des voies métaboliques conduisant à la biosynthèse des lipides de réserve. La disponibilité de mutants et de lignées transgéniques d’Arabidopsis et le développement de puces à ADN qui permettent l’analyse simultanée de plusieurs milliers de gènes conduiront à une meilleure compréhension des facteurs qui régulent le métabolisme des huiles dans les graines. Une telle connaissance facilitera la manipulation de la composition des huiles et des quantités produites dans les graines.

  4. Comparative in silico analyses of Cannabis sativa, Prunella vulgaris and Withania somnifera compounds elucidating the medicinal properties against rheumatoid arthritis.

    Science.gov (United States)

    Zaka, Mehreen; Sehgal, Sheikh Arslan; Shafique, Shagufta; Abbasi, Bilal Haider

    2017-06-01

    From last decade, there has been progressive improvement in computational drug designing. Several diseases are being cured from different plant extracts and products. Rheumatoid Arthritis (RA) is the most shared disease among auto-inflammatory diseases. Tumour necrosis factor (TNF)-α is associated with RA pathway and has adverse effects. Extensive literature review showed that plant species under study (Cannabis sativa, Prunella vulgaris and Withania somnifera) possess anti-inflammatory, anti-arthritic and anti-rheumatic properties. 13 anti-inflammatory compounds were characterised and filtered out from medicinal plant species and analysed for RA by targeting TNF-α through in silico analyses. By using ligand based pharmacophore generation approach and virtual screening against natural products libraries we retrieved twenty unique molecules that displayed utmost binding affinity, least binding energies and effective drug properties. The docking analyses revealed that Ala-22, Glu-23, Ser-65, Gln-67, Tyr-141, Leu-142, Asp-143, Phe-144 and Ala-145 were critical interacting residues for receptor-ligand interactions. It is proposed that the RA patients should use reported compounds for the prescription of RA by targeting TNF-α. This report is opening new dimensions for designing innovative therapeutic targets to cure RA. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Comparative analyses of microbial structures and gene copy numbers in the anaerobic digestion of various types of sewage sludge.

    Science.gov (United States)

    Hidaka, Taira; Tsushima, Ikuo; Tsumori, Jun

    2018-04-01

    Anaerobic co-digestion of various sewage sludges is a promising approach for greater recovery of energy, but the process is more complicated than mono-digestion of sewage sludge. The applicability of microbial structure analyses and gene quantification to understand microbial conditions was evaluated. The results show that information from gene analyses is useful in managing anaerobic co-digestion and damaged microbes in addition to conventional parameters like total solids, pH and biogas production. Total bacterial 16S rRNA gene copy numbers are the most useful tools for evaluating unstable anaerobic digestion of sewage sludge, rather than mcrA and total archaeal 16S rRNA gene copy numbers, and high-throughput sequencing. First order decay rates of gene copy numbers during pH failure were higher than typical decay rates of microbes in stable operation. The sequencing analyses, including multidimensional scaling, showed very different microbial structure shifts, but the results were not consistent. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Cloning, characterisation, and comparative quantitative expression analyses of receptor for advanced glycation end products (RAGE) transcript forms.

    Science.gov (United States)

    Sterenczak, Katharina A; Willenbrock, Saskia; Barann, Matthias; Klemke, Markus; Soller, Jan T; Eberle, Nina; Nolte, Ingo; Bullerdiek, Jörn; Murua Escobar, Hugo

    2009-04-01

    RAGE is a member of the immunoglobulin superfamily of cell surface molecules playing key roles in pathophysiological processes, e.g. immune/inflammatory disorders, Alzheimer's disease, diabetic arteriosclerosis and tumourigenesis. In humans 19 naturally occurring RAGE splicing variants resulting in either N-terminally or C-terminally truncated proteins were identified and are lately discussed as mechanisms for receptor regulation. Accordingly, deregulation of sRAGE levels has been associated with several diseases e.g. Alzheimer's disease, Type 1 diabetes, and rheumatoid arthritis. Administration of recombinant sRAGE to animal models of cancer blocked tumour growth successfully. In spite of its obvious relationship to cancer and metastasis data focusing sRAGE deregulation and tumours is rare. In this study we screened a set of tumours, healthy tissues and various cancer cell lines for RAGE splicing variants and analysed their structure. Additionally, we analysed the ratio of the mainly found transcript variants using quantitative Real-Time PCR. In total we characterised 24 previously not described canine and 4 human RAGE splicing variants, analysed their structure, classified their characteristics, and derived their respective protein forms. Interestingly, the healthy and the neoplastic tissue samples showed in majority RAGE transcripts coding for the complete receptor and transcripts showing insertions of intron 1.

  7. Analyses comparatives de productions écrites d'apprenants de français et de locuteurs francophones, à l'aide d'outils d'extraction automatique du langage

    Directory of Open Access Journals (Sweden)

    Jean-Gabriel Ganascia

    2005-11-01

    Full Text Available De nouveaux logiciels d'analyse textuelle tirent parti des progrès récents effectués en apprentissage symbolique et dans le traitement automatique des langues naturelles. Conçu au LIP6 par Jean-Gabriel Ganascia, le Littératron est l'un d'entre eux ; il extrait automatiquement des motifs syntaxiques à partir de textes écrits en langage naturel. Plus exactement, le Littératron prend comme entrée un arbre d'analyse syntaxique et donne en sortie un certain nombre de motifs syntaxiques récurrents. Associé à un analyseur de textes, qui engendre l'arbre d'analyse syntaxique à partir de textes écrits en langage naturel, il révèle les singularités stylistiques de ces textes. Nous allons voir qu'utilisé en sciences du langage, dans le domaine de l'acquisition du français écrit, le Littératron effectue un diagnostic linguistique de l'apprenant, que celui-ci provienne d'une classe de langue hétérogène (différentes langues maternelles ou homogène (une seule langue maternelle, en l'occurrence ici l'arabe. L'intérêt de cette approche concerne trois domaines : d'une part la didactique des langues, à titre éducatif ; d'autre part, la linguistique computationnelle, et enfin l'enseignement assisté par ordinateur.

  8. Effects of (Des-Tyr1)-γ-endorphin and α-endorphin as compared to haloperidol and amphetamine on nucleus accumbens self-stimulation

    NARCIS (Netherlands)

    Ree, J.M. van; Otte, A.P.

    The β-endorphin fragment (Des-Tyr1)-γ-endorphin (DTγE, β-LPH 62–77) attenuated self-stimulation behaviour associated with electrical stimulation of the nucleus accumbens area of rats. This effect was observed after subcutaneous (s.c.) injection of 2.5 and 25 μg of the neuropeptide and appeared to be

  9. Étude de la compétitivité de complexation des métaux issus des ...

    African Journals Online (AJOL)

    Les analyses chimiques effectuées sur le phosphate naturel révèlent la présence des métaux lourds. Pour étudier les risques de rétrogradation de ces engrais phosphatés, notre étude s'est portée sur la complexation des substances humiques naturelles extraites des sols sur des ions métalliques tels que le calcium, ...

  10. Recherches en didactique des mathématiques Volume 29/2 - 2009

    OpenAIRE

    Dorier, Jean-Luc; Robert, Aline

    2009-01-01

    La revue Recherches en didactique des mathématiques entend rendre compte des recherches fondamentales menées dans le cadre de la Didactique des Mathématiques. Il s’agit d’une revue de recherche qui publie des articles originaux concernant : - la détermination des faits pertinents de la communication didactique ; - l’analyse de situations d’enseignement créées par les professeurs ou proposées par l’expérimentateur ; - l’analyse des conduites et productions des élèves au cours d’un apprentissag...

  11. Comparative study of the ionic exchange of Ca{sup ++}, Sr{sup ++}, and Ba{sup ++} cations on resins and inorganic exchangers; Etude comparative de l'echange ionique des cations Ca{sup ++}, Sr{sup ++} et Ba{sup ++} sur resine et sur echangeurs mineraux

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez Batanero, P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1969-03-01

    With a view to applying the results to certain problems related to chemical separations in activation analysis, a study has been made, of the possibilities of separating the alkaline-earth elements Ca, Sr and Ba on organic resins and inorganic exchangers using the radioactive indicator method. The partition coefficients of the cations Ca{sup 2+}, Sr{sup 2+} and Ba{sup 2+} have been measured on Dowex 50 W (NH{sub 4}{sup +}) x 8 resin in the presence of EDTA - NTA - EGTA and DCTA as complexing agents, and on zirconium phosphate, tungstate and molybdate in the presence of HCl and NH{sub 4}Cl. Methods have been developed for separating mixtures of alkaline-earth elements using DCTA-NH{sub 4}{sup +} followed by elution on Dowex 50 W (NH{sub 4}{sup +}) x 8 resin columns and on zirconium phosphate. Amongst the complexing agents used on the ion-exchange resins the most promising appears to be DCTA which leads to partition coefficients Ca, Sr and Ba which are very different. The results of measurements of partition coefficients on zirconium phosphate (NH{sub 4}{sup +} form) using DCTA-NH{sub 4}{sup +} show the interesting possibilities of separations on columns. The separation of the alkaline-earth elements on zirconium phosphate seems to be less quantitative than on Dowex 50 resin; it is however much faster in the former case and this can be useful for treating short half-life radioisotopes in activation analysis. (author) [French] En vue de l'application a certains problemes de separations chimiques en analyse par activation, on a etudie les possibilites de separation des elements alcalino-terreux Ca-Sr et Ba sur resine organique et sur echangeurs mineraux par la methode des indicateurs radioactifs. Les coefficients de partage des cations Ca{sup +2}, Sr{sup +2} et Ba{sup +2} sur resine Dowex 50 W (NH{sub 4}{sup +}) x 8 en milieux complexants EDTA - NTA - EGTA et DCTA et sur phosphate, tungstate et molybdate de zirconium en milieu HCl et NH{sub 4}Cl ont ete mesures. Des

  12. Switching to olanzapine long-acting injection from either oral olanzapine or any other antipsychotic: comparative post hoc analyses

    Directory of Open Access Journals (Sweden)

    Ciudad A

    2013-11-01

    Full Text Available Antonio Ciudad,1 Ernie Anand,2 Lovisa Berggren,3 Marta Casillas,4 Alexander Schacht,3 Elena Perrin5 1Department of Clinical Research and Development, Eli Lilly & Co, Madrid, Spain; 2Neuroscience Medical Affairs – EU, Lilly Research Centre, Windlesham, Surrey, UK; 3Global Statistical Sciences, Eli Lilly & Co, Bad Homburg, Germany; 4European Scientific Communications, Eli Lilly & Co, Madrid, Spain; 5Medical Department, Eli Lilly & Co, Suresnes, Paris, France Background: A considerable proportion of patients suffering from schizophrenia show suboptimal responses to oral antipsychotics due to inadequate adherence. Hence, they are likely to benefit from switching to a long-acting injectable formulation. These post hoc analyses assessed the clinical effects of switching to olanzapine long-acting injection (OLAI from either oral olanzapine (OLZ or other antipsychotics (non-OLZ. Methods: Post hoc analyses were done based on two randomized studies (one short-term, one long-term conducted in patients suffering from schizophrenia and treated with OLAI. The short-term study was an 8-week placebo-controlled, double-blind trial in acute patients, and the long-term study was a 2-year, oral olanzapine-controlled, open-label, follow-up of stabilized outpatients. Results: These analyses used data from 62 OLAI-treated patients (12 switched from OLZ, 50 from non-OLZ from the short-term study and 190 OLAI-treated patients (56 switched from OLZ, 134 from non-OLZ from the long-term study. Kaplan–Meier survival analyses of time to all-cause discontinuation of OLAI treatment did not differ significantly between OLZ and non-OLZ patients in the short-term study (P=0.209 or long-term study (P=0.448. Similarly, the proportions of OLZ and non-OLZ patients that discontinued OLAI were not statistically different in the short-term (16.7% versus 36.0%, respectively; P=0.198 or long-term (57.1% versus 47.8% respectively; P=0.238 studies. In the short-term study, no

  13. Locoregional recurrence of rectal carcinoma. A CT-analysis and a target volume concept in adjuvant radiotherapy; Das lokoregionaere Rezidiv des Rektumkarzinoms. Eine computertomographische Analyse und ein Zielvolumenkonzept fuer die adjuvante Radiotherapie

    Energy Technology Data Exchange (ETDEWEB)

    Bagatzounis, A. [Wuerzburg Univ. (Germany). Klinik und Poliklinik fuer Strahlentherapie; Koelbl, O. [Wuerzburg Univ. (Germany). Klinik und Poliklinik fuer Strahlentherapie; Mueller, G. [Wuerzburg Univ. (Germany). Klinik und Poliklinik fuer Strahlentherapie; Oppitz, U. [Wuerzburg Univ. (Germany). Klinik und Poliklinik fuer Strahlentherapie; Willner, J. [Wuerzburg Univ. (Germany). Klinik und Poliklinik fuer Strahlentherapie; Flentje, M. [Wuerzburg Univ. (Germany). Klinik und Poliklinik fuer Strahlentherapie

    1997-02-01

    Patients and method: 155 patients with the diagnosis of rectal carcinoma recurrences were treated in our institution between 1980 and 1995. To determine the extension of the recurrent tumor within the pelvic levels (praesacral levels S1-S5, precoccygeal-, pelvic floor level and perineal level) and the tumor infiltration of pelvic organs and muscles we analysed the pretherapeutic CT-images. The lymphnode recurrences were classified as: Pararectal-, presacral-, iliac internal-, iliac external-, iliac communis- and paraaortal recurrences. Results: Sixty-one percent of the patients with rectum exstirpation and 66% with anterior resection showed a combined local and nodal recurrence. Isolated lymph node recurrences were rare (4% and 5%). The local recurrence was mostly situated in the presacral pelvis, predominantly there was an infiltration of the presacral space at the level of S4, S5 and os coccygis regardless of the operating method and the primary tumor location. The anastomosis was involved in the tumor recurrence in 93% of the anteriorly resected patients. In 9 out of 96 patients after rectum exstirpation the pelvic region caudal of the tip of the coccyx was the origin of the recurrent tumor. Primarily all 9 patients had a deep-seated carcinoma (<6 cm ab ano). Only 2 patients showed an isolated perineal recurrence after rectum exstirpation. Two thirds of the deepseated tumors showed a vaginal involvement. The incidence of iliac internal- and presacral nodal recurrence was 47 to 59%. The incidence of iliac external lymph node recurrences was 7% after rectum exstirpation and 2% after anterior resection/Hartmann procedure. (orig./AJ) [Deutsch] Patienten und Methode: 155 Patienten wurden in unserer Klinik im Zeitraum 1980 bis 1995 wegen eines Rektumkarzinomrezidivs behandelt. Die Rezidivausdehnung inn