WorldWideScience

Sample records for amelx tri-tyrosyl domain

  1. Domains and domain loss

    DEFF Research Database (Denmark)

    Haberland, Hartmut

    2005-01-01

    politicians and in the media, especially in the discussion whether some languages undergo ‘domain loss’ vis-à-vis powerful international languages like English. An objection that has been raised here is that domains, as originally conceived, are parameters of language choice and not properties of languages...... theoretical constructs that can explain language choice which were supposed to be a more powerful explanatory tool than more obvious (and observable) parameters like topic, place (setting) and interlocutor. In the meantime, at least in Scandinavia, the term ‘domain’ has been taken up in the debate among...

  2. Domain Engineering

    Science.gov (United States)

    Bjørner, Dines

    Before software can be designed we must know its requirements. Before requirements can be expressed we must understand the domain. So it follows, from our dogma, that we must first establish precise descriptions of domains; then, from such descriptions, “derive” at least domain and interface requirements; and from those and machine requirements design the software, or, more generally, the computing systems.

  3. Domain crossing

    DEFF Research Database (Denmark)

    Schraefel, M. C.; Rouncefield, Mark; Kellogg, Wendy; Ackerman, Mark; Marsden, Gary; Bødker, Susanne; Wyche, Susan; Reddy, Madhu

    In CSCW, how much do we need to know about another domain/culture before we observe, intersect and intervene with designs. What optimally would that other culture need to know about us? Is this a “how long is a piece of string” question, or an inquiry where we can consider a variety of contexts a...

  4. Trusted Domain

    DEFF Research Database (Denmark)

    Hjorth, Theis Solberg; Torbensen, Rune

    2012-01-01

    remote access via IP-based devices such as smartphones. The Trusted Domain platform fits existing legacy technologies by managing their interoperability and access controls, and it seeks to avoid the security issues of relying on third-party servers outside the home. It is a distributed system that......In the digital age of home automation and with the proliferation of mobile Internet access, the intelligent home and its devices should be accessible at any time from anywhere. There are many challenges such as security, privacy, ease of configuration, incompatible legacy devices, a wealth of...

  5. Protein domain prediction

    NARCIS (Netherlands)

    Ingolfsson, Helgi; Yona, Golan

    2008-01-01

    Domains are considered to be the building blocks of protein structures. A protein can contain a single domain or multiple domains, each one typically associated with a specific function. The combination of domains determines the function of the protein, its subcellular localization and the interacti

  6. Adapting Mathematical Domain Reasoners

    CERN Document Server

    Heeren, Bastiaan

    2010-01-01

    Mathematical learning environments help students in mastering mathematical knowledge. Mature environments typically offer thousands of interactive exercises. Providing feedback to students solving interactive exercises requires domain reasoners for doing the exercise-specific calculations. Since a domain reasoner has to solve an exercise in the same way a student should solve it, the structure of domain reasoners should follow the layered structure of the mathematical domains. Furthermore, learners, teachers, and environment builders have different requirements for adapting domain reasoners, such as providing more details, disallowing or enforcing certain solutions, and combining multiple mathematical domains in a new domain. In previous work we have shown how domain reasoners for solving interactive exercises can be expressed in terms of rewrite strategies, rewrite rules, and views. This paper shows how users can adapt and configure such domain reasoners to their own needs. This is achieved by enabling users...

  7. Diamagnetic (Condon) domains

    International Nuclear Information System (INIS)

    This paper is the first systematic review of experimental research on diamagnetic (aka Condon) domains that form in nonmagnetic metals at low temperatures due to the development of Landau levels. A variety of methods were used to study the domains. Muon spectroscopy studies showed such domains to be present in all metals studied, pointing to the universal nature of the phenomenon. For silver, the domain structure size as measured by Hall microsensors turned out to be an order of magnitude larger than expected. In beryllium, it was found that domains do not come to the surface but rather remain in the bulk of the crystal. The magnetostriction of beryllium during domain formation is measured. It is shown that magnetization current in a domain wall is entirely caused by the charge density gradient in the wall, due to the lattice being deformed oppositely in neighboring domains. It is observed for the first time that the de Haas-van Alphen effect exhibits hysteresis at the transition to the domain state, and this fact was used for the experimental determination of the phase diagrams for the domain states of silver and beryllium. (reviews of topical problems)

  8. Frustratingly Easy Domain Adaptation

    CERN Document Server

    Daumé, Hal

    2009-01-01

    We describe an approach to domain adaptation that is appropriate exactly in the case when one has enough ``target'' data to do slightly better than just using only ``source'' data. Our approach is incredibly simple, easy to implement as a preprocessing step (10 lines of Perl!) and outperforms state-of-the-art approaches on a range of datasets. Moreover, it is trivially extended to a multi-domain adaptation problem, where one has data from a variety of different domains.

  9. CULTURAL DOMAINS: TRANSLATION PROBLEMS

    OpenAIRE

    Isabel Negro Alousque

    2009-01-01

    Much of the lexis of a language has a cultural referent and is thus specific to a speech community. The meaning of culturally marked words is often difficult to grasp without some cultural knowledge and poses translation problems, particularly when the words are associated with cultural domains (Nida, 2001). In the present paper we focus on the French cultural domain of cooking. After outlining the elements of the domain, we analyse the difficulties in translating the lexical units from the d...

  10. Visualizing latent domain knowledge

    OpenAIRE

    Chen, C.; Kuljis, J; Paul, RJ

    2001-01-01

    Knowledge discovery and data mining commonly rely on finding salient patterns of association from a vast amount of data. Traditional citation analysis of scientific literature draws insights from strong citation patterns. Latent domain knowledge, in contrast to the mainstream domain knowledge, often consists of highly relevant but relatively infrequently cited scientific works. Visualizing latent domain knowledge presents a significant challenge to knowledge discovery and quantitative studies...

  11. Topological Domain Theory

    OpenAIRE

    Battenfeld, Ingo

    2008-01-01

    This thesis presents Topological Domain Theory as a powerful and flexible framework for denotational semantics. Topological Domain Theory models a wide range of type constructions and can interpret many computational features. Furthermore, it has close connections to established frameworks for denotational semantics, as well as to well-studied mathematical theories, such as topology and computable analysis.

  12. Modeling Protein Domain Function

    Science.gov (United States)

    Baker, William P.; Jones, Carleton "Buck"; Hull, Elizabeth

    2007-01-01

    This simple but effective laboratory exercise helps students understand the concept of protein domain function. They use foam beads, Styrofoam craft balls, and pipe cleaners to explore how domains within protein active sites interact to form a functional protein. The activity allows students to gain content mastery and an understanding of the…

  13. Domain Walls on Singularities

    CERN Document Server

    Halyo, Edi

    2009-01-01

    We describe domain walls that live on $A_2$ and $A_3$ singularities. The walls are BPS if the singularity is resolved and non--BPS if it is deformed and fibered. We show that these domain walls may interpolate between vacua that support monopoles and/or vortices.

  14. Feature-Level Domain Adaptation

    OpenAIRE

    Kouw, Wouter M.; Krijthe, Jesse H.; Loog, Marco; van der Maaten, Laurens J. P.

    2015-01-01

    Domain adaptation is the supervised learning setting in which the training and test data originate from different domains: the so-called source and target domains. In this paper, we propose and study a domain adaption approach, called feature-level domain adaptation (flda), that models the dependence between two domains by means of a feature-level transfer distribution. The domain adapted classifier is trained by minimizing the expected loss under this transfer distribution. Our empirical eva...

  15. Domain-Specific Multimodeling

    DEFF Research Database (Denmark)

    Hessellund, Anders

    Enterprise systems are complex artifacts. They are hard to build, manage, understand, and evolve. Existing software development paradigms fail to properly address challenges such as system size, domain complexity, and software evolution when development is scaled to enterprise systems. We propose...... domain-specific multimodeling as a development paradigm to tackle these challenges in a language-oriented manner. The different concerns of a system are conceptually separated and made explicit as independent domain-specific languages. This approach increases productivity and quality by raising the...

  16. Visualizing Knowledge Domains.

    Science.gov (United States)

    Borner, Katy; Chen, Chaomei; Boyack, Kevin W.

    2003-01-01

    Reviews visualization techniques for scientific disciplines and information retrieval and classification. Highlights include historical background of scientometrics, bibliometrics, and citation analysis; map generation; process flow of visualizing knowledge domains; measures and similarity calculations; vector space model; factor analysis;…

  17. Conserved Domain Database (CDD)

    Data.gov (United States)

    U.S. Department of Health & Human Services — CDD is a protein annotation resource that consists of a collection of well-annotated multiple sequence alignment models for ancient domains and full-length proteins.

  18. Axion domain wall baryogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Daido, Ryuji; Kitajima, Naoya [Department of Physics, Tohoku University,Sendai 980-8578 (Japan); Takahashi, Fuminobu [Department of Physics, Tohoku University,Sendai 980-8578 (Japan); Kavli IPMU, TODIAS, University of Tokyo,Kashiwa 277-8583 (Japan)

    2015-07-28

    We propose a new scenario of baryogenesis, in which annihilation of axion domain walls generates a sizable baryon asymmetry. Successful baryogenesis is possible for a wide range of the axion mass and decay constant, m≃10{sup 8}–10{sup 13} GeV and f≃10{sup 13}–10{sup 16} GeV. Baryonic isocurvature perturbations are significantly suppressed in our model, in contrast to various spontaneous baryogenesis scenarios in the slow-roll regime. In particular, the axion domain wall baryogenesis is consistent with high-scale inflation which generates a large tensor-to-scalar ratio within the reach of future CMB B-mode experiments. We also discuss the gravitational waves produced by the domain wall annihilation and its implications for the future gravitational wave experiments.

  19. Domain Theory for Concurrency

    DEFF Research Database (Denmark)

    Nygaard, Mikkel

    Concurrent computation can be given an abstract mathematical treatment very similar to that provided for sequential computation by domain theory and denotational semantics of Scott and Strachey. A simple domain theory for concurrency is presented. Based on a categorical model of linear logic and...... nondeterministic dataflow. The domain theory can be generalised to presheaf models, providing a more refined treatment of nondeterministic branching and supporting notions of bisimulation. The operational semantics for HOPLA is guided by the idea that derivations of transitions in the operational semantics should...... correspond to elements of the presheaf denotations. Similar guidelines lead to an operational semantics for the first-order fragment of Affine HOPLA. An extension of the operational semantics to the full language is based on a stable denotational semantics which associates to each computation the minimal...

  20. Large domain graphene

    OpenAIRE

    Li, Xuesong; Magnuson, Carl W.; Venugopal, Archana; Vogel, Eric M.; Rodney S. Ruoff; Colombo, Luigi

    2010-01-01

    Graphene growth by chemical vapor deposition has received a lot of attention recently owing to the ease with which large area films can be grown, but growth of large domain or equivalently large grain size has not been reported yet. In this brevia, we report on a CVD process that yields graphene with domains of hundreds of micrometers, by very low pressure CVD, less than 50 mTorr, and very low precursor flow rates using methane as the source of carbon on the inside of copper foil enclosures a...

  1. Atomic Pseudo-Valuation Domains

    CERN Document Server

    Stines, Elijah

    2012-01-01

    Pseudo-valuation domains have been studied since their introduction in 1978 by Hedstrom and Houston. Related objects, boundary valuation domains, were introduced by Maney in 2004. Here, it is shown that the class of atomic pseudo-valuation domains coincides with the class of boundary valuation domains. It is also shown that power series rings and generalized power series rings give examples of pseudo-valuation domains whose congruence lattices can be characterized. The paper also introduces, and makes use of, a sufficient condition on the group of divisibility of a domain to guarantee that it is a pseudo-valuation domain.

  2. Domain: Labour market

    NARCIS (Netherlands)

    Oude Mulders, J.; Wadensjö, E.; Hasselhorn, H.M.; Apt, W.

    2015-01-01

    This domain chapter is dedicated to summarize research on the effects of labour market contextual factors on labour market participation of older workers (aged 50+) and identify research gaps. While employment participation and the timing of (early) retirement is often modelled as an individual deci

  3. Skyrmions and domain walls

    OpenAIRE

    Piette, B.; Zakrzewski, W. J.

    1997-01-01

    We study the 3+1 dimensional Skyrme model with a mass term different from the usual one. We show that this new model possesses domain walls solutions. We describe how, in the equivalent 2+1 dimensional model, the Skyrmion is absorbed by the wall.

  4. Fuzzy Bases of Fuzzy Domains

    OpenAIRE

    Sanping Rao; Qingguo Li

    2013-01-01

    This paper is an attempt to develop quantitative domain theory over frames. Firstly, we propose the notion of a fuzzy basis, and several equivalent characterizations of fuzzy bases are obtained. Furthermore, the concept of a fuzzy algebraic domain is introduced, and a relationship between fuzzy algebraic domains and fuzzy domains is discussed from the viewpoint of fuzzy basis. We finally give an application of fuzzy bases, where the image of a fuzzy domain can be preserved under some special ...

  5. Atomic Pseudo-Valuation Domains

    OpenAIRE

    Stines, Elijah

    2012-01-01

    Pseudo-valuation domains have been studied since their introduction in 1978 by Hedstrom and Houston. Related objects, boundary valuation domains, were introduced by Maney in 2004. Here, it is shown that the class of atomic pseudo-valuation domains coincides with the class of boundary valuation domains. It is also shown that power series rings and generalized power series rings give examples of pseudo-valuation domains whose congruence lattices can be characterized. The paper also introduces, ...

  6. Cross-Domain Sparse Coding

    OpenAIRE

    Wang, Jim Jing-Yan

    2013-01-01

    Sparse coding has shown its power as an effective data representation method. However, up to now, all the sparse coding approaches are limited within the single domain learning problem. In this paper, we extend the sparse coding to cross domain learning problem, which tries to learn from a source domain to a target domain with significant different distribution. We impose the Maximum Mean Discrepancy (MMD) criterion to reduce the cross-domain distribution difference of sparse codes, and also ...

  7. Time Domain Induced Polarization

    DEFF Research Database (Denmark)

    Fiandaca, Gianluca; Auken, Esben; Christiansen, Anders Vest;

    2012-01-01

    Time-domain-induced polarization has significantly broadened its field of reference during the last decade, from mineral exploration to environmental geophysics, e.g., for clay and peat identification and landfill characterization. Though, insufficient modeling tools have hitherto limited the use...... of time-domaininduced polarization for wider purposes. For these reasons, a new forward code and inversion algorithm have been developed using the full-time decay of the induced polarization response, together with an accurate description of the transmitter waveform and of the receiver transfer...... is above 100%. Furthermore, the presence of low-pass filters in time-domain-induced polarization instruments affects the early times of the acquired decays (typically up to 100 ms) and has to be modeled in the forward response to avoid significant loss of resolution. The developed forward code has...

  8. Domain-specific languages

    OpenAIRE

    Jasný, Vojtěch

    2009-01-01

    The topic of the thesis are domain-specific languages (DSL) and their use in software development. The target audience are developers interested in learning more about this progressive area of software development. It starts with a necessary theoretical introduction to programming languages. Then, a classification of DSLs is given and software development methodologies based on DSLs are described, notably Language Oriented Programming and Intentional Programming. Another important piece in co...

  9. Implementing maritime domain awareness

    OpenAIRE

    Watts, Robert B.

    2006-01-01

    CHDS State/Local As an attempt to gain understanding of everything in the global maritime environment that can impact the security of the United States, the Maritime Domain Awareness initiative is one of the most ambitious projects ever undertaken by the U.S. government. Information that falls under the prevue of MDA is tremendously diverse and complex, having application in the regulatory, law enforcement, and military arenas. As such, MDA is a multi-agency effort that encompasses 16 resp...

  10. Domain decomposition method for solving elliptic problems in unbounded domains

    International Nuclear Information System (INIS)

    Computational aspects of the box domain decomposition (DD) method for solving boundary value problems in an unbounded domain are discussed. A new variant of the DD-method for elliptic problems in unbounded domains is suggested. It is based on the partitioning of an unbounded domain adapted to the given asymptotic decay of an unknown function at infinity. The comparison of computational expenditures is given for boundary integral method and the suggested DD-algorithm. 29 refs.; 2 figs.; 2 tabs

  11. Comparison of the domain and frequency domain state feedbacks

    International Nuclear Information System (INIS)

    In this paper, we present explicitly the equivalence of the time domain and frequency domain state feedbacks, as well as the dynamic state feedback and a modified frequency domain state feedback, from the closed-loop transfer function point of view. The difference of the two approaches is also shown

  12. On Free Z-domains%自由Z-domain

    Institute of Scientific and Technical Information of China (English)

    姚丽娟; 徐晓泉

    2011-01-01

    给出由偏序集生成的自由Z-domain,讨论自由Z-domain和偏序集的Dedekind-MacNeille完备化的一些性质.%The free Z-domains generated by posets are given.Some properties of tte free Z-domains and the Dedekind-MacNeille completions of posets are investigated.

  13. Summarization by domain ontology navigation

    DEFF Research Database (Denmark)

    Andreasen, Troels; Bulskov, Henrik

    2013-01-01

    of the subject. In between these two extremes, conceptual summaries encompass selected concepts derived using background knowledge. We address in this paper an approach where conceptual summaries are provided through a conceptualization as given by an ontology. The ontology guiding the summarization can...... be a simple taxonomy or a generative domain ontology. A domain ontology can be provided by a preanalysis of a domain corpus and can be used to condense improved summaries that better reflects the conceptualization of a given domain....

  14. Domain Engineering: An Empirical Study

    OpenAIRE

    Harris, Charles; Frakes, William B.

    2006-01-01

    This paper presents a summary and analysis of data gathered from thirteen domain engineering projects, participant surveys, and demographic information. Taking a failure modes approach, project data is compared to an ideal model of the DARE methodology, revealing valuable insights into points of failure in the domain engineering process. This study suggests that success is a function of the domain analyst’s command of a specific set of domain engineering concepts and skills, the time invested...

  15. A Convenient Category of Domains

    OpenAIRE

    Battenfeld, Ingo; Schröder, Matthias; Simpson, Alexander

    2007-01-01

    We motivate and define a category of topological domains, whose objects are certain topological spaces, generalising the usual ω-continuous dcppos of domain theory. Our category supports all the standard constructions of domain theory, including the solution of recursive domain equations. It also supports the construction of free algebras for (in)equational theories, can be used as the basis for a theory of computability, and provides a model of parametric polymorphism.

  16. A convenient category of domains

    OpenAIRE

    Battenfeld, Ingo; Schröder, Matthias; Simpson, Alex

    2007-01-01

    We motivate and define a category of "topological domains", whose objects are certain topological spaces, generalising the usual $omega$-continuous dcppos of domain theory. Our category supports all the standard constructions of domain theory, including the solution of recursive domain equations. It also supports the construction of free algebras for (in)equational theories, provides a model of parametric polymorphism, and can be used as the basis for a theory of computab...

  17. Frequency domain nonlinear optics

    Science.gov (United States)

    Legare, Francois

    2016-05-01

    The universal dilemma of gain narrowing occurring in fs amplifiers prevents ultra-high power lasers from delivering few-cycle pulses. This problem is overcome by a new amplification concept: Frequency domain Optical Parametric Amplification - FOPA. It enables simultaneous up-scaling of peak power and amplified spectral bandwidth and can be performed at any wavelength range of conventional amplification schemes, however, with the capability to amplify single cycles of light. The key idea for amplification of octave-spanning spectra without loss of spectral bandwidth is to amplify the broad spectrum ``slice by slice'' in the frequency domain, i.e. in the Fourier plane of a 4f-setup. The striking advantages of this scheme, are its capability to amplify (more than) one octave of bandwidth without shorting the corresponding pulse duration. This is because ultrabroadband phase matching is not defined by the properties of the nonlinear crystal employed but the number of crystals employed. In the same manner, to increase the output energy one simply has to increase the spectral extension in the Fourier plane and to add one more crystal. Thus, increasing pulse energy and shortening its duration accompany each other. A proof of principle experiment was carried out at ALLS on the sub-two cycle IR beam line and yielded record breaking performance in the field of few-cycle IR lasers. 100 μJ two-cycle pulses from a hollow core fibre compression setup were amplified to 1.43mJ without distorting spatial or temporal properties. Pulse duration at the input of FOPA and after FOPA remains the same. Recently, we have started upgrading this system to be pumped by 250 mJ to reach 40 mJ two-cycle IR few-cycle pulses and latest results will be presented at the conference. Furthermore, the extension of the concept of FOPA to other nonlinear optical processes will be discussed. Frequency domain nonlinear optics.

  18. Domain Bridging Associations Support Creativity

    OpenAIRE

    Kötter, Tobias; Thiel, Kilian; Berthold, Michael R

    2010-01-01

    This paper proposes a new approach to support creativity through assisting the discovery of unexpected associations across different domains. This is achieved by integrating information from heterogeneous domains into a single network, enabling the interactive discovery of links across the corresponding information resources. We discuss three different pattern of domain crossing associations in this context.

  19. Expansion of protein domain repeats.

    Directory of Open Access Journals (Sweden)

    Asa K Björklund

    2006-08-01

    Full Text Available Many proteins, especially in eukaryotes, contain tandem repeats of several domains from the same family. These repeats have a variety of binding properties and are involved in protein-protein interactions as well as binding to other ligands such as DNA and RNA. The rapid expansion of protein domain repeats is assumed to have evolved through internal tandem duplications. However, the exact mechanisms behind these tandem duplications are not well-understood. Here, we have studied the evolution, function, protein structure, gene structure, and phylogenetic distribution of domain repeats. For this purpose we have assigned Pfam-A domain families to 24 proteomes with more sensitive domain assignments in the repeat regions. These assignments confirmed previous findings that eukaryotes, and in particular vertebrates, contain a much higher fraction of proteins with repeats compared with prokaryotes. The internal sequence similarity in each protein revealed that the domain repeats are often expanded through duplications of several domains at a time, while the duplication of one domain is less common. Many of the repeats appear to have been duplicated in the middle of the repeat region. This is in strong contrast to the evolution of other proteins that mainly works through additions of single domains at either terminus. Further, we found that some domain families show distinct duplication patterns, e.g., nebulin domains have mainly been expanded with a unit of seven domains at a time, while duplications of other domain families involve varying numbers of domains. Finally, no common mechanism for the expansion of all repeats could be detected. We found that the duplication patterns show no dependence on the size of the domains. Further, repeat expansion in some families can possibly be explained by shuffling of exons. However, exon shuffling could not have created all repeats.

  20. Metaphors, domains and embodiment

    Directory of Open Access Journals (Sweden)

    M.E. Botha

    2005-07-01

    Full Text Available Investigations of metaphorical meaning constitution and meaning (in- variance have revealed the significance of semantic and semiotic domains and the contexts within which they function as basis for the grounding of metaphorical meaning. In this article some of the current views concerning the grounding of metaphorical meaning in experience and embodiment are explored. My provisional agreement with Lakoff, Johnson and others about the “conceptual” nature of metaphor rests on an important caveat, viz. that this bodily based conceptual structure which lies at the basis of linguistic articulations of metaphor, is grounded in a deeper ontic structure of the world and of human experience. It is the “metaphorical” (actually “analogical” ontological structure of this grounding that is of interest for the line of argumentation followed in this article. Because Johnson, Lakoff and other’s proposal to ground metaphorical meaning in embodiment and neural processes is open to being construed as subjectivist and materialist, I shall attempt to articulate the contours of an alternative theory of conceptual metaphor, meaning and embodiment which counteracts these possibilities. This theory grounds metaphorical meaning and meaning change in an ontological and anthropological framework which recognises the presence and conditioning functioning of radially ordered structures for reality. These categorisations in which humankind, human knowledge and reality participate, condition and constrain (ground analogical and metaphorical meaning transfer, cross-domain mappings, and blends in cognition and in language, provide the basis for the analogical concepts found in these disciplines.

  1. Ligand binding by PDZ domains

    DEFF Research Database (Denmark)

    Chi, Celestine N.; Bach, Anders; Strømgaard, Kristian;

    2012-01-01

    The postsynaptic density protein-95/disks large/zonula occludens-1 (PDZ) protein domain family is one of the most common protein-protein interaction modules in mammalian cells, with paralogs present in several hundred human proteins. PDZ domains are found in most cell types, but neuronal proteins......, for example, are particularly rich in these domains. The general function of PDZ domains is to bring proteins together within the appropriate cellular compartment, thereby facilitating scaffolding, signaling, and trafficking events. The many functions of PDZ domains under normal physiological as well...

  2. The framing of scientific domains

    DEFF Research Database (Denmark)

    Dam Christensen, Hans

    2014-01-01

    according to the agents that are charting them. As such, power in a Foucauldian sense is unavoidable in outlining a domain. Originality/value 1. The UNISIST models are applied to the domain of art history; and 2. the article discusses the instability of a scientific domain as well as, at the same time, the......Purpose: By using the UNISIST models this article argues for the necessity of domain analysis in order to qualify scientific information seeking. The models better understanding of communication processes in a scientific domain and embraces the point that domains are always both unstable over time...... and changeable according to the specific perspective. This understanding is even more important today as numerous digitally generated information tools as well as collaborative and interdisciplinary research are blurring the domain borders. Nevertheless, researchers navigate “intuitively” in “their...

  3. Protein domain organisation: adding order

    Directory of Open Access Journals (Sweden)

    Kummerfeld Sarah K

    2009-01-01

    Full Text Available Abstract Background Domains are the building blocks of proteins. During evolution, they have been duplicated, fused and recombined, to produce proteins with novel structures and functions. Structural and genome-scale studies have shown that pairs or groups of domains observed together in a protein are almost always found in only one N to C terminal order and are the result of a single recombination event that has been propagated by duplication of the multi-domain unit. Previous studies of domain organisation have used graph theory to represent the co-occurrence of domains within proteins. We build on this approach by adding directionality to the graphs and connecting nodes based on their relative order in the protein. Most of the time, the linear order of domains is conserved. However, using the directed graph representation we have identified non-linear features of domain organization that are over-represented in genomes. Recognising these patterns and unravelling how they have arisen may allow us to understand the functional relationships between domains and understand how the protein repertoire has evolved. Results We identify groups of domains that are not linearly conserved, but instead have been shuffled during evolution so that they occur in multiple different orders. We consider 192 genomes across all three kingdoms of life and use domain and protein annotation to understand their functional significance. To identify these features and assess their statistical significance, we represent the linear order of domains in proteins as a directed graph and apply graph theoretical methods. We describe two higher-order patterns of domain organisation: clusters and bi-directionally associated domain pairs and explore their functional importance and phylogenetic conservation. Conclusion Taking into account the order of domains, we have derived a novel picture of global protein organization. We found that all genomes have a higher than expected

  4. Domain wall networks on solitons

    International Nuclear Information System (INIS)

    Domain wall networks on the surface of a soliton are studied in a simple theory. It consists of two complex scalar fields, in 3+1 dimensions, with a global U(1)xZn symmetry, where n>2. Solutions are computed numerically in which one of the fields forms a Q ball and the other field forms a network of domain walls localized on the surface of the Q ball. Examples are presented in which the domain walls lie along the edges of a spherical polyhedron, forming junctions at its vertices. It is explained why only a small restricted class of polyhedra can arise as domain wall networks

  5. Gears, Pregears and Related Domains

    OpenAIRE

    Brown, Philip R.; Porter, R. Michael

    2015-01-01

    We study conformal mappings from the unit disk to one-toothed gear-shaped planar domains from the point of view of the Schwarzian derivative. Gear-shaped (or "gearlike") domains fit into a more general category of domains we call "pregears" (images of gears under Mobius transformations), which aid in the study of the conformal mappings for gears and which we also describe in detail. Such domains being bounded by arcs of circles, the Schwarzian derivative of the Riemann mapping is known to be ...

  6. Taxonomies of Educational Objective Domain

    Directory of Open Access Journals (Sweden)

    Eman Ghanem Nayef

    2013-09-01

    Full Text Available This paper highlights an effort to study the educational objective domain taxonomies including Bloom’s taxonomy, Lorin Anderson’s taxonomy, and Wilson’s taxonomy. In this study a comparison among these three taxonomies have been done. Results show that Bloom’s taxonomy is more suitable as an analysis tool to Educational Objective domain.

  7. Taxonomies of Educational Objective Domain

    OpenAIRE

    Eman Ghanem Nayef; Nik Rosila Nik Yaacob; Hairul Nizam Ismail

    2013-01-01

    This paper highlights an effort to study the educational objective domain taxonomies including Bloom’s taxonomy, Lorin Anderson’s taxonomy, and Wilson’s taxonomy. In this study a comparison among these three taxonomies have been done. Results show that Bloom’s taxonomy is more suitable as an analysis tool to Educational Objective domain.

  8. Texture of lipid bilayer domains

    DEFF Research Database (Denmark)

    Jensen, Uffe Bernchou; Brewer, Jonathan R.; Midtiby, Henrik Skov; Ipsen, John Hjort; Bagatolli, Luis; Simonsen, Adam Cohen

    2009-01-01

    We investigate the texture of gel (g) domains in binary lipid membranes composed of the phospholipids DPPC and DOPC. Lateral organization of lipid bilayer membranes is a topic of fundamental and biological importance. Whereas questions related to size and composition of fluid membrane domain are...... chains. By imaging the intensity variations as a function of the polarization angle, we map the lateral variations of the lipid tilt within domains. Results reveal that gel domains are composed of subdomains with different lipid tilt directions. We have applied a Fourier decomposition method as a...... which correlates with the phase state of the membrane. This is quantified by the generalized polarization (GP) function, and we demonstrate that a GP analysis can be performed on supported membranes. The results show that although the gel domains have heterogeneous texture, the membrane phase state does...

  9. Static properties of Condon domains

    International Nuclear Information System (INIS)

    A new nonlinear differential equation is used for description of the static properties of domain walls of magnetic domains of the non-spin type (Condon domains). This equation is derived on the basis of the exact expression for the thermodynamic potential density, enabling taking into account the oscillating behavior of the magnetization. Inhomogeneity is included in the generalized equation of state. The derived equation is solved analytically. A new shape of the domain wall is presented by the new kink solution of the obtained equation. The width and surface tension of the domain wall is presented as a function of the magnetic field strength, temperature, and Dingle temperature. They exhibit the critical behavior typical of the mean-field theory of second-order phase transitions. The calculated critical exponents are in agreement with nuclear magnetic resonance, muon spin-rotation spectroscopy and Hall probes measurements.

  10. Control of magnetic domains and domain walls by themal gradients

    OpenAIRE

    Stärk, Martin

    2015-01-01

    The aim of this work is to study heat effects in thin magnetic films to verify the theoretical prediction of domain wall motion towards a heat source. In the theory, a domain wall moves from a cold region towards the hotter part due to energy minimization processes. It is shown that no electron transport is necessary for this effect as it has been observed in insulators. An analytical model describes the effective field that acts on a domain wall as an external applied magnetic field. This is pr...

  11. Information Fusion: Moving from domain independent to domain literate approaches

    Science.gov (United States)

    McGuinness, D.

    2008-12-01

    Information Fusion has been a focus of research within the field of computer science for a number of years. Numerous environments aimed at general schema evaluation, diagnosis, and evolution have evolved within those communities including for example the Chimaera Ontology Evolution Environment and the Prompt environment for mapping schema alignment. General (domain independent) efforts have produced useful research results and numerous tools, however these results have predominantly been generated and used by computer scientists and have been focused largely on information schema integration and diagnosis. More recently semantically-enabled web-centric approaches have emerged that utilize domain knowledge to provide tools and services aimed at natural scientists needs for data fusion. In this talk, we will introduce some foundations for information fusion and provide deployed examples of how these foundations and evolving tools have been and are being used today in natural science domains by domain scientists. Some examples will be provided from deployed virtual observatory settings.

  12. Pixel-Level Domain Transfer

    OpenAIRE

    Yoo, Donggeun; Kim, Namil; Park, Sunggyun; Paek, Anthony S.; Kweon, In So

    2016-01-01

    We present an image-conditional image generation model. The model transfers an input domain to a target domain in semantic level, and generates the target image in pixel level. To generate realistic target images, we employ the real/fake-discriminator in Generative Adversarial Nets, but also introduce a novel domain-discriminator to make the generated image relevant to the input image. We verify our model through a challenging task of generating a piece of clothing from an input image of a dr...

  13. Partial domain wall partition functions

    OpenAIRE

    Foda, O.; Wheeler, M.

    2012-01-01

    We consider six-vertex model configurations on an n-by-N lattice, n =< N, that satisfy a variation on domain wall boundary conditions that we define and call "partial domain wall boundary conditions". We obtain two expressions for the corresponding "partial domain wall partition function", as an (N-by-N)-determinant and as an (n-by-n)-determinant. The latter was first obtained by I Kostov. We show that the two determinants are equal, as expected from the fact that they are partition functions...

  14. Wavefield extrapolation in pseudodepth domain

    KAUST Repository

    Ma, Xuxin

    2013-02-01

    Wavefields are commonly computed in the Cartesian coordinate frame. Its efficiency is inherently limited due to spatial oversampling in deep layers, where the velocity is high and wavelengths are long. To alleviate this computational waste due to uneven wavelength sampling, we convert the vertical axis of the conventional domain from depth to vertical time or pseudodepth. This creates a nonorthognal Riemannian coordinate system. Isotropic and anisotropic wavefields can be extrapolated in the new coordinate frame with improved efficiency and good consistency with Cartesian domain extrapolation results. Prestack depth migrations are also evaluated based on the wavefield extrapolation in the pseudodepth domain.© 2013 Society of Exploration Geophysicists. All rights reserved.

  15. Engineered CH2 domains (nanoantibodies).

    Science.gov (United States)

    Dimitrov, Dimiter S

    2009-01-01

    Currently, almost all FDA approved therapeutic antibodies (except ReoPro, Lucentis and Cimzia which are Fabs), and the vast majority of those in clinical trials are full-size antibodies mostly in IgG1 format of about 150 kDa size. A fundamental problem for such large molecules is their poor penetration into tissues (e.g., solid tumors) and poor or absent binding to regions on the surface of some molecules (e.g., on the HIV envelope glycoprotein) which are fully accessible only by molecules of smaller size. Therefore, much work especially during the last decade has been aimed at developing novel scaffolds of much smaller size and high stability. Here I briefly describe a proposition to use the immunoglobulin (Ig) constant CH2 domain (CH3 for IgE and IgM) as a scaffold. CH2 is critical for the Ig effector functions. Isolated CH2 is stable monomer in contrast to all other constant domains and most of the variable domains. CH2 and engineered CH2 domains with improved stability can be used as scaffolds for construction of libraries containing diverse binders to various antigens. Such binders based on a CH2 scaffold could also confer some effector functions. Because the CH2 domains are the smallest independently folded antibody domains that can be engineered to contain simultaneously antigen-binding sites and binding sites mediating effector and stability functions, and to distinguish them from domain antibodies which are used to denote engineered VH or VL domains or nanobodies which are used to denote camelid VHH, I termed them nanoantibodies (nAbs). PMID:20046570

  16. Domain Decomposition Solvers for Frequency-Domain Finite Element Equations

    KAUST Repository

    Copeland, Dylan

    2010-10-05

    The paper is devoted to fast iterative solvers for frequency-domain finite element equations approximating linear and nonlinear parabolic initial boundary value problems with time-harmonic excitations. Switching from the time domain to the frequency domain allows us to replace the expensive time-integration procedure by the solution of a simple linear elliptic system for the amplitudes belonging to the sine- and to the cosine-excitation or a large nonlinear elliptic system for the Fourier coefficients in the linear and nonlinear case, respectively. The fast solution of the corresponding linear and nonlinear system of finite element equations is crucial for the competitiveness of this method. © 2011 Springer-Verlag Berlin Heidelberg.

  17. Functional domain walls in multiferroics

    Science.gov (United States)

    Meier, Dennis

    2015-11-01

    During the last decade a wide variety of novel and fascinating correlation phenomena has been discovered at domain walls in multiferroic bulk systems, ranging from unusual electronic conductance to inseparably entangled spin and charge degrees of freedom. The domain walls represent quasi-2D functional objects that can be induced, positioned, and erased on demand, bearing considerable technological potential for future nanoelectronics. Most of the challenges that remain to be solved before turning related device paradigms into reality, however, still fall in the field of fundamental condensed matter physics and materials science. In this topical review seminal experimental findings gained on electric and magnetic domain walls in multiferroic bulk materials are addressed. A special focus is put on the physical properties that emerge at so-called charged domain walls and the added functionality that arises from coexisting magnetic order. The research presented in this review highlights that we are just entering a whole new world of intriguing nanoscale physics that is yet to be explored in all its details. The goal is to draw attention to the persistent challenges and identify future key directions for the research on functional domain walls in multiferroics.

  18. Domain walls at finite temperature

    International Nuclear Information System (INIS)

    It is suggested that the phase transition of lambda phi 4 theory as a function of temperature coincides with the spontaneous appearance of domain walls. Based on one-loop calculations, T sub(c) = 4M/√ lambda is estimated as the temperature for these domains to because energetically favored, to be compared with T sub(c) = 4.9M/√ lambda from effective potential calculations (which are performed directly in the broken phase). Domain walls, as well as other Types of fluctuations, disorder the system above T sub(c), leading to =0. The critical exponent for the specific heat above T sub(c) is computed; and α=2/3 + 0 (√ lambda) is obtained. (Author)

  19. Learning processes across knowledge domains

    DEFF Research Database (Denmark)

    Hall-Andersen, Lene Bjerg; Broberg, Ole

    2014-01-01

    Purpose - The purpose of this paper is to shed light on the problematics of learning across knowledge boundaries in organizational settings. The paper specifically explores learning processes that emerge, when a new knowledge domain is introduced into an existing organizational practice...... informed by selected perspectives on learning processes and boundary processes was applied on three illustrative vignettes to illuminate learning potentials and shortcomings in boundary processes. Findings - In the engineering consultancy, it was found that while learning did occur in the consultancy...... between knowledge domains. Research limitations/implications - The finding in this paper is based on a single case study: hence, the findings' generalizability may be limited. Practical implications - The paper argues that learning across knowledge domains needs various forms of supporting initiatives...

  20. Improving the performance of DomainDiscovery of protein domain boundary assignment using inter-domain linker index

    Directory of Open Access Journals (Sweden)

    Zomaya Albert Y

    2006-12-01

    Full Text Available Abstract Background Knowledge of protein domain boundaries is critical for the characterisation and understanding of protein function. The ability to identify domains without the knowledge of the structure – by using sequence information only – is an essential step in many types of protein analyses. In this present study, we demonstrate that the performance of DomainDiscovery is improved significantly by including the inter-domain linker index value for domain identification from sequence-based information. Improved DomainDiscovery uses a Support Vector Machine (SVM approach and a unique training dataset built on the principle of consensus among experts in defining domains in protein structure. The SVM was trained using a PSSM (Position Specific Scoring Matrix, secondary structure, solvent accessibility information and inter-domain linker index to detect possible domain boundaries for a target sequence. Results Improved DomainDiscovery is compared with other methods by benchmarking against a structurally non-redundant dataset and also CASP5 targets. Improved DomainDiscovery achieves 70% accuracy for domain boundary identification in multi-domains proteins. Conclusion Improved DomainDiscovery compares favourably to the performance of other methods and excels in the identification of domain boundaries for multi-domain proteins as a result of introducing support vector machine with benchmark_2 dataset.

  1. Domain wall description of superconductivity

    International Nuclear Information System (INIS)

    In the present work we shall address the issue of electrical conductivity in superconductors in the perspective of superconducting domain wall solutions in the realm of field theory. We take our set up made out of a dynamical complex scalar field coupled to gauge field to be responsible for superconductivity and an extra scalar real field that plays the role of superconducting domain walls. The temperature of the system is interpreted through the fact that the soliton following accelerating orbits is a Rindler observer experiencing a thermal bath

  2. Automorphism group of exceptional symmetric domains RVI

    Institute of Scientific and Technical Information of China (English)

    许以超

    2000-01-01

    Here we give the definition of the exceptional symmetric Siegel domain RVI (27) in (?)27, and compute the exceptional symmetric domain .RvI(27) = r(RVI(27)), where τ is the Bergman mapping of the Siegel domain RVI(27). Moreover, we present the holomorphical automorphism group Aut(.RVI|(27)) of the exceptional symmetric domain .

  3. Computations of Bergman Kernels on Hua Domains

    Institute of Scientific and Technical Information of China (English)

    殷慰萍; 王安; 赵振刚; 赵晓霞; 管冰辛

    2001-01-01

    @@The Bergman kernel function plays an important ro1e in several complex variables.There exists the Bergman kernel function on any bounded domain in Cn. But we can get the Bergman kernel functions in explicit formulas for a few types of domains only,for example:the bounded homogeneous domains and the egg domain in some cases.

  4. Protein structural domains: definition and prediction.

    Science.gov (United States)

    Ezkurdia, Iakes; Tress, Michael L

    2011-11-01

    Recognition and prediction of structural domains in proteins is an important part of structure and function prediction. This unit lists the range of tools available for domain prediction, and describes sequence and structural analysis tools that complement domain prediction methods. Also detailed are the basic domain prediction steps, along with suggested strategies for different protein sequences and potential pitfalls in domain boundary prediction. The difficult problem of domain orientation prediction is also discussed. All the resources necessary for domain boundary prediction are accessible via publicly available Web servers and databases and do not require computational expertise. PMID:22045561

  5. Ubiquitin domain proteins in disease

    DEFF Research Database (Denmark)

    Klausen, Louise Kjær; Schulze, Andrea; Seeger, Michael;

    2007-01-01

    The human genome encodes several ubiquitin-like (UBL) domain proteins (UDPs). Members of this protein family are involved in a variety of cellular functions and many are connected to the ubiquitin proteasome system, an essential pathway for protein degradation in eukaryotic cells. Despite their...... and cancer. Publication history: Republished from Current BioData's Targeted Proteins database (TPdb; http://www.targetedproteinsdb.com)....

  6. Domain Building or Risk Taking

    DEFF Research Database (Denmark)

    Hjort, Katrin; Abrahamsen, Marianne

    2012-01-01

    of the relations between gender, values and family obligation but reveals an interesting difference between two strategies for career development: Domain Building and Risk Taking. Both strategies are applied by both men and women. However, one of them seems to be the most effective with regard to achieve...

  7. Modules over discrete valuation domains

    CERN Document Server

    Tuganbaev, Askar A

    2008-01-01

    This book provides the first systematic treatment of modules over discrete valuation domains which plays an important role in various areas of algebra, especially in commutative algebra. Many important results representing the state of the art are presented in the text which is supplemented by exercises and interesting open problems. An important contribution to commutative algebra.

  8. Partial domain wall partition functions

    CERN Document Server

    Foda, O

    2012-01-01

    We consider six-vertex model configurations on a rectangular lattice with n (N) horizontal (vertical) lines, and "partial domain wall boundary conditions" defined as 1. all 2n arrows on the left and right boundaries point inwards, 2. n_u (n_l) arrows on the upper (lower) boundary, such that n_u + n_l = N - n, also point inwards, 3. all remaining n+N arrows on the upper and lower boundaries point outwards, and 4. all spin configurations on the upper and lower boundaries are summed over. To generate (n-by-N) "partial domain wall configurations", one can start from A. (N-by-N) configurations with domain wall boundary conditions and delete n_u (n_l) upper (lower) horizontal lines, or B. (2n-by-N) configurations that represent the scalar product of an n-magnon Bethe eigenstate and an n-magnon generic state on an N-site spin-1/2 chain, and delete the n lines that represent the Bethe eigenstate. The corresponding "partial domain wall partition function" is computed in construction {A} ({B}) as an N-by-N (n-by-n) det...

  9. Weakly distributive domains(Ⅱ)

    Institute of Scientific and Technical Information of China (English)

    JIANG Ying; ZHANG Guo-Qiang

    2007-01-01

    In our previous work(Inform.and Comput.,2005,202:87-103),we have shown that for any ω-algebraic meet-cpo D,if all higher-order stable function spaces built from D are ω-algebraic,then D is finitary.This accomplishes the first of a possible,two-step process in solving the problem raised(LNCS,1991,530:16-33;Domainsand lambda-calculi,Cambridge Univ.Press,1998)whetherthe category of stable bifinite domains of Amadio-Droste-G(o)bel(LNCS,1991,530:16-33;Theor.Comput.Sci.,1993,111:89-101)is the largest cartesian closed full subcategory within the category of ω-algebraic meet-cpos with stable functions.This paper presents the results of the second step,which is to show that for any ω-algebraic meet-cpo D satisfying axioms M and I to be contained in a cartesian closed full sub-category using ω-algebraic meet-cpos with stable functions,it must not violate M I∞.We introduce a new class of domains called weakly distributive domains and show that for these domains to be in a cartesian closed category using ω-algebraic meet-cpos,property M I must not be violated.Further,we demonstrate that principally distributive domains(those for which each principle ideal is distributive)form a proper subclass of weakly distributive domains,and Birkhoff's M3 and N5(Introduction to Lattices and order,Cambridge Univ.Press,2002)are weakly distributive(but non-distributive).Then,we establish characterization results for weakly distributive domains.We also introduce the notion of meet-generators in constructing stable functions and show that if an ω-algebraic meet-cpo D contains an infinite number of meet-generators,then[D→D]fails I.However,the original problem of Amadio and Curien remains open.

  10. Compiling Dictionaries Using Semantic Domains*

    Directory of Open Access Journals (Sweden)

    Ronald Moe

    2011-10-01

    Full Text Available

    Abstract: The task of providing dictionaries for all the world's languages is prodigious, re-quiring efficient techniques. The text corpus method cannot be used for minority languages lacking texts. To meet the need, the author has constructed a list of 1 600 semantic domains, which he has successfully used to collect words. In a workshop setting, a group of speakers can collect as many as 17 000 words in ten days. This method results in a classified word list that can be efficiently expanded into a full dictionary. The method works because the mental lexicon is a giant web or-ganized around key concepts. A semantic domain can be defined as an important concept together with the words directly related to it by lexical relations. A person can utilize the mental web to quickly jump from word to word within a domain. The author is developing a template for each domain to aid in collecting words and in de-scribing their semantics. Investigating semantics within the context of a domain yields many in-sights. The method permits the production of both alphabetically and semantically organized dic-tionaries. The list of domains is intended to be universal in scope and applicability. Perhaps due to universals of human experience and universals of linguistic competence, there are striking simi-larities in various lists of semantic domains developed for languages around the world. Using a standardized list of domains to classify multiple dictionaries opens up possibilities for cross-lin-guistic research into semantic and lexical universals.

    Keywords: SEMANTIC DOMAINS, SEMANTIC FIELDS, SEMANTIC CATEGORIES, LEX-ICAL RELATIONS, SEMANTIC PRIMITIVES, DOMAIN TEMPLATES, MENTAL LEXICON, SEMANTIC UNIVERSALS, MINORITY LANGUAGES, LEXICOGRAPHY

    Opsomming: Samestelling van woordeboeke deur gebruikmaking van se-mantiese domeine. Die taak van die voorsiening van woordeboeke aan al die tale van die wêreld is geweldig en vereis doeltreffende tegnieke. Die

  11. Decomposition and Removability Properties of John Domains

    Indian Academy of Sciences (India)

    M Huang; S Ponnusamy; X Wang

    2008-08-01

    In this paper we characterize John domains in terms of John domain decomposition property. In addition, we also show that a domain in $\\mathbb{R}^n$ is a John domain if and only if $D\\backslash P$ is a John domain, where is a subset of containing finitely many points of . The best possibility and an application of the second result are also discussed.

  12. PUBLIC DOMAIN PROTECTION. USES AND REUSES OF PUBLIC DOMAIN WORKS

    Directory of Open Access Journals (Sweden)

    Monica Adriana LUPAȘCU

    2015-07-01

    Full Text Available This study tries to highlight the necessity of an awareness of the right of access to the public domain, particularly using the example of works whose protection period has expired, as well as the ones which the law considers to be excluded from protection. Such works are used not only by large libraries from around the world, but also by rights holders, via different means of use, including incorporations into original works or adaptations. However, the reuse that follows these uses often only remains at the level of concept, as the notion of the public’s right of access to public domain works is not substantiated, nor is the notion of the correct or legal use of such works.

  13. The three-domain model

    OpenAIRE

    Nakata, Miyuki; Okada, Kiyotaka

    2012-01-01

    Blade outgrowth and region-specific cell differentiation are crucial events during the early development of plant leaves, and the progression of both of these events requires a normal adaxial-abaxial pattern. In a recent study, we had demonstrated that two WUSCHEL-RELATED HOMEOBOX (WOX) family genes, i.e., PRESSED FLOWER (PRS) and WOX1, act redundantly in blade outgrowth and adaxial-abaxial patterning. During leaf development, the two genes are expressed in the domain between the adaxial and ...

  14. Superconductivity in domains with corners

    DEFF Research Database (Denmark)

    Bonnaillie-Noel, Virginie; Fournais, Søren

    2007-01-01

    We study the two-dimensional Ginzburg-Landau functional in a domain with corners for exterior magnetic field strengths near the critical field where the transition from the superconducting to the normal state occurs. We discuss and clarify the definition of this field and obtain a complete...... asymptotic expansion for it in the large $\\kappa$ regime. Furthermore, we discuss nucleation of superconductivity at the boundary....

  15. Categorization in the Affective Domain

    DEFF Research Database (Denmark)

    Sauciuc, Gabriela-Alina

    2011-01-01

    Data collected in Romance and Scandinavian languages (N=474) in a superordinate category name production task indicate that a multiple-strategy approach would be more suitable for accounting of categorization in the affective domain instead of a prototype approach as suggested by previous studies....... This paper will highlight performance aspects which appear to be consistent with such an interpretation, as well as an important layman- expert knowledge asymmetry in affective categorization....

  16. Flexible time domain averaging technique

    Science.gov (United States)

    Zhao, Ming; Lin, Jing; Lei, Yaguo; Wang, Xiufeng

    2013-09-01

    Time domain averaging(TDA) is essentially a comb filter, it cannot extract the specified harmonics which may be caused by some faults, such as gear eccentric. Meanwhile, TDA always suffers from period cutting error(PCE) to different extent. Several improved TDA methods have been proposed, however they cannot completely eliminate the waveform reconstruction error caused by PCE. In order to overcome the shortcomings of conventional methods, a flexible time domain averaging(FTDA) technique is established, which adapts to the analyzed signal through adjusting each harmonic of the comb filter. In this technique, the explicit form of FTDA is first constructed by frequency domain sampling. Subsequently, chirp Z-transform(CZT) is employed in the algorithm of FTDA, which can improve the calculating efficiency significantly. Since the signal is reconstructed in the continuous time domain, there is no PCE in the FTDA. To validate the effectiveness of FTDA in the signal de-noising, interpolation and harmonic reconstruction, a simulated multi-components periodic signal that corrupted by noise is processed by FTDA. The simulation results show that the FTDA is capable of recovering the periodic components from the background noise effectively. Moreover, it can improve the signal-to-noise ratio by 7.9 dB compared with conventional ones. Experiments are also carried out on gearbox test rigs with chipped tooth and eccentricity gear, respectively. It is shown that the FTDA can identify the direction and severity of the eccentricity gear, and further enhances the amplitudes of impulses by 35%. The proposed technique not only solves the problem of PCE, but also provides a useful tool for the fault symptom extraction of rotating machinery.

  17. Domains of bosonic functional integrals

    International Nuclear Information System (INIS)

    We propose a mathematical framework for bosonic Euclidean quantum field functional integrals based on the theory of integration on the dual algebraic vector space of classical field sources. We present a generalization of the Minlos-Dao Xing theorem and apply it to determine exactly the domain of integration associated to the functional integral representation of the two-dimensional quantum electrodynamics Schwinger generating functional. (author)

  18. Finite Domain Bounds Consistency Revisited

    OpenAIRE

    Choi, Chiu Wo; Harvey, Warwick; Lee, Jimmy Ho-Man; Stuckey, Peter J.

    2004-01-01

    A widely adopted approach to solving constraint satisfaction problems combines systematic tree search with constraint propagation for pruning the search space. Constraint propagation is performed by propagators implementing a certain notion of consistency. Bounds consistency is the method of choice for building propagators for arithmetic constraints and several global constraints in the finite integer domain. However, there has been some confusion in the definition of bounds consistency. In t...

  19. Subharmonic Fourier domain mode locking.

    Science.gov (United States)

    Eigenwillig, Christoph M; Wieser, Wolfgang; Biedermann, Benjamin R; Huber, Robert

    2009-03-15

    We demonstrate a subharmonically Fourier domain mode-locked wavelength-swept laser source with a substantially reduced cavity fiber length. In contrast to a standard Fourier domain mode-locked configuration, light is recirculated repetitively in the delay line with the optical bandpass filter used as switch. The laser has a fundamental optical round trip frequency of 285 kHz and can be operated at integer fractions thereof (subharmonics). Sweep ranges up to 95 nm full width centred at 1317 nm are achieved at the 1/5th subharmonic. A maximum sensitivity of 116 dB and an axial resolution of 12 microm in air are measured at an average sweep power of 12 mW. A sensitivity roll-off of 11 dB over 4 mm and 25 dB over 10 mm is observed and optical coherence tomography imaging is demonstrated. Besides the advantage of a reduced fiber length, subharmonic Fourier domain mode locking (shFDML) enables simple scaling of the sweep speed by extracting light from the delay part of the resonator. A sweep rate of 570 kHz is achieved. Characteristic features of shFDML operation, such as power leakage during fly-back and cw breakthrough, are investigated. PMID:19282912

  20. Dynamics of domain wall networks

    International Nuclear Information System (INIS)

    Networks or webs of domain walls are admitted in Abelian or non-Abelian gauge theory coupled to fundamental Higgs fields with complex masses. We examine the dynamics of the domain wall loops by using the moduli approximation and find a phase rotation induces a repulsive force which can be understood as a Noether charge of Q-solitons. Non-Abelian gauge theory allows different types of loops which can be deformed to each other by changing a modulus. This admits the moduli geometry like a sandglass made by gluing the tips of the two cigar-(cone-)like metrics of a single triangle loop. We conclude that the sizes of all loops tend to grow for a late time in general models with complex Higgs masses, while the sizes are stabilized at some values once triplet masses are introduced for the Higgs fields. We also show that the stationary motion on the moduli space of the domain wall webs represents 1/4 Bogomol'nyi-Prasad-Sommerfield Q-webs of walls

  1. Beyond cross-domain learning: Multiple-domain nonnegative matrix factorization

    KAUST Repository

    Wang, Jingyan

    2014-02-01

    Traditional cross-domain learning methods transfer learning from a source domain to a target domain. In this paper, we propose the multiple-domain learning problem for several equally treated domains. The multiple-domain learning problem assumes that samples from different domains have different distributions, but share the same feature and class label spaces. Each domain could be a target domain, while also be a source domain for other domains. A novel multiple-domain representation method is proposed for the multiple-domain learning problem. This method is based on nonnegative matrix factorization (NMF), and tries to learn a basis matrix and coding vectors for samples, so that the domain distribution mismatch among different domains will be reduced under an extended variation of the maximum mean discrepancy (MMD) criterion. The novel algorithm - multiple-domain NMF (MDNMF) - was evaluated on two challenging multiple-domain learning problems - multiple user spam email detection and multiple-domain glioma diagnosis. The effectiveness of the proposed algorithm is experimentally verified. © 2013 Elsevier Ltd. All rights reserved.

  2. A Domain Standard for Land Administration

    OpenAIRE

    Lemmen, C.; Van Oosterom, P.; P. Van Der Molen

    2013-01-01

    This paper presents the design of a Domain Model for Land Administration (LA). As a result a formal International Standard is available: ISO 19152 Geographic Information – Land Administration Domain Model (LADM) (ISO, 2012). Domain specific standardisation is needed to capture the semantics of the land administration domain on top of the agreed foundation of basic standards for geometry, temporal aspects, metadata and also observations and measurements from the field. A standard is required f...

  3. Issues in Planning Domain Model Engineering

    OpenAIRE

    McCluskey, T.L.; Vaquero, Tiago; Vallati, Mauro

    2016-01-01

    The paper raises some issues relating to the engineering of domain models for automated planning. It studies the idea of a domain model as a formal specification of a domain, and considers properties of that specification. It proposes some definitions, which the planning and, more generally, the artificial intelligence community needs to consider, in order to properly deal with engineering issues in domain model creation.

  4. Application Domain Name-Based Analysis

    OpenAIRE

    Peter Václavík

    2009-01-01

    Information about the problem domain of the software and the solution it implements is often embedded by developers in comments and identifiers. When using software developed by others or when are new to a project, programmers know little about how domain information is reflected in the source code. In the paper, the way to establish a commonly used domain vocabulary automatically is presented. Two domains have been selected: application servers and web frameworks. In the paper we are also in...

  5. DENN Domain Proteins: Regulators of Rab GTPases*

    OpenAIRE

    Marat, Andrea L.; Dokainish, Hatem; McPherson, Peter S

    2011-01-01

    The DENN domain is a common, evolutionarily ancient, and conserved protein module, yet it has gone largely unstudied; until recently, little was known regarding its functional roles. New studies reveal that various DENN domains interact directly with members of the Rab family of small GTPases and that DENN domains function enzymatically as Rab-specific guanine nucleotide exchange factors. Thus, DENN domain proteins appear to be generalized regulators of Rab function. Study of these proteins w...

  6. Bisociative Discovery of Interesting Relations between Domains

    OpenAIRE

    Nagel, Uwe; Thiel, Kilian; Kötter, Tobias; Piatek, Dawid; Berthold, Michael

    2011-01-01

    The discovery of surprising relations in large, heterogeneous information repositories is gaining increasing importance in real world data analysis. If these repositories come from diverse origins, forming different domains, domain bridging associations between otherwise weakly connected domains can provide insights into the data that can otherwise not be accomplished. In this paper, we propose a first formalization for the detection of such potentially interesting, domain-crossing relations ...

  7. Multiple graph regularized protein domain ranking

    OpenAIRE

    Wang Jim; Bensmail Halima; Gao Xin

    2012-01-01

    Abstract Background Protein domain ranking is a fundamental task in structural biology. Most protein domain ranking methods rely on the pairwise comparison of protein domains while neglecting the global manifold structure of the protein domain database. Recently, graph regularized ranking that exploits the global structure of the graph defined by the pairwise similarities has been proposed. However, the existing graph regularized ranking methods are very sensitive to the choice of the graph m...

  8. Identification of alternative topological domains in chromatin

    OpenAIRE

    Filippova, Darya; Patro, Rob; Duggal, Geet; Kingsford, Carl

    2014-01-01

    Chromosome conformation capture experiments have led to the discovery of dense, contiguous, megabase-sized topological domains that are similar across cell types and conserved across species. These domains are strongly correlated with a number of chromatin markers and have since been included in a number of analyses. However, functionally-relevant domains may exist at multiple length scales. We introduce a new and efficient algorithm that is able to capture persistent domains across various r...

  9. Multiscale Identification of Topological Domains in Chromatin

    OpenAIRE

    Filippova, Darya; Patro, Rob; Duggal, Geet; Kingsford, Carl

    2013-01-01

    Recent chromosome conformation capture experiments have led to the discovery of dense, contiguous, megabase-sized topological domains that are similar across cell types and conserved across species. These domains are strongly correlated with a number of chromatin markers and have since been included in a number of analyses. However, functionally-relevant domains may exist at multiple length scales. We introduce a new and efficient algorithm that is able to capture persistent domains across va...

  10. A Domain Standard for Land Administration

    NARCIS (Netherlands)

    Lemmen, C.; Van Oosterom, P.; Van der Molen, P.

    2013-01-01

    This paper presents the design of a Domain Model for Land Administration (LA). As a result a formal International Standard is available: ISO 19152 Geographic Information – Land Administration Domain Model (LADM) (ISO, 2012). Domain specific standardisation is needed to capture the semantics of the

  11. Convex mappings on some circular domains

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    In this paper,we consider some circular domains.And we give an extension theorem for some normalized biholomorphic convex mapping on some circular domains.Especially,we discover the normalized biholomorphic convex mapping on some circular domains have the form f(z) =(f1(z1),...,fn(zn)),where fj:D → C are normalized biholomorphic convex mapping.

  12. Casimir force for cosmological domain walls

    OpenAIRE

    Matsuda, Tomohiro

    2011-01-01

    We calculate the vacuum fluctuations that may affect the evolution of cosmological domain walls. Considering domain walls, which are classically stable and have interaction with a scalar field, we show that explicit symmetry violation in the interaction may cause quantum bias that can solve the cosmological domain wall problem.

  13. Safe domain and elementary geometry

    CERN Document Server

    Richard, J M

    2004-01-01

    A classical problem of mechanics involves a projectile fired from a given point with a given velocity whose direction is varied. This results in a family of trajectories whose envelope defines the border of a 'safe' domain. In the simple cases of a constant force, harmonic potential and Kepler or Coulomb motion, the trajectories are conic curves whose envelope in a plane is another conic section which can be derived either by simple calculus or by geometrical considerations. The case of harmonic forces reveals a subtle property of the maximal sum of distances within an ellipse.

  14. Structuring very large domain models

    DEFF Research Database (Denmark)

    Störrle, Harald

    2010-01-01

    a lower level of detail have not been dealt with. This paper aims at filling this gap by reporting personal experiences from a very large scale industrial domain modeling project. There, structuring the logical view turned out to be a critical success factor. We explain the project and its setting......, analyze the role and repercussions of model structuring, and examine the implications model structuring decisions have on other parts of the project. We then explain the model structure abstracted from a very large scale industrial modeling project. Finally, we discuss lessons learned....

  15. The Promise of Domain Adaptation

    Science.gov (United States)

    Mahabal, Ashish A.; Li, Jingling; Vaijanapurkar, Samarth; Bue, Brian; Miller, Adam; Donalek, Ciro; Djorgovski, Stanislav G.; Drake, Andrew J.; Graham, Matthew; CRTS, iPTF

    2016-01-01

    Most new surveys spend an appreciable time in collecting data on which to train classifiers before they can be used on future observations from the same dataset. The result generating phase can start much earlier if the training could incorporate data accumulated from older surveys enhanced with a small set from the new survey. This is exactly what Domain Adaptation (DA) allows us to do. The main idea behind DAs can be summarized thus: if we have two classes of separable objects in some feature space of a Source survey (S), we can define a hyperplane to separate the two types. In a second Target survey (T), for the same features the hyperplane would be inclined differently. DA methods get the mapping between the two hyperplanes using a small fraction of data from the Target (T) survey and can then be used to predict the classes of the remaining majority of data in T. We discuss the parameters that need to be tuned, the difficulties involved, and ways to improve the results. As we move towards bigger, and deeper surveys, being able to use existing labelled information to conduct classification in future surveys will be more cost-effective and promote time efficiency as well. Starting with the light curve data of 50,000 periodic objects from Catalina Real-Time Transient Survey (CRTS), we have applied domain adaptation techniques such as Geodesic Flow Kernel (GFK) with Random forest classifier and Co-training for domain adaptation (CODA) to the CRTS data which has 35,000 points overlapping with Palomar Transient Factory (PTF), and 12,000 with Lincoln Near-Earth Asteroid Research (LINEAR). The results suggest that domain adaptation is an area worth exploring as the knowledge between these surveys is transferable and the approaches to find the mappings between these surveys can be applied to the remaining data as well as for near future surveys such as CRTS-II, Zwicky Transient Facility (ZTF) and the Large Synoptic Survey Telescope (LSST) to name a few at the optical

  16. New Massive Gravity Domain Walls

    CERN Document Server

    dS, U Camara

    2010-01-01

    The properties of the asymptotic $AdS_3$ space-times representing flat domain walls (DW's) solutions of the New Massive 3D Gravity with scalar matter are studied. Our analysis is based on $I^{st}$ order BPS-like equations involving an appropriate superpotential. The Brown-York boundary stress-tensor is used for the calculation of DW's tensions as well as of the $CFT_2$'s central charges. The holographic renormalization group flows and the phase transitions in specific deformed $CFT_2$ dual to 3D massive gravity model with quadratic superpotential are discussed.

  17. Faraday instability in deformable domains

    International Nuclear Information System (INIS)

    Hydrodynamical instabilities are usually studied either in bounded regions or free to grow in space. In this article we review the experimental results of an intermediate situation, in which an instability develops in deformable domains. The Faraday instability, which consists in the formation of surface waves on a liquid experiencing a vertical forcing, is triggered in floating liquid lenses playing the role of deformable domains. Faraday waves deform the lenses from the initial circular shape and the mutual adaptation of instability patterns with the lens boundary is observed. Two archetypes of behaviour have been found. In the first archetype a stable elongated shape is reached, the wave vector being parallel to the direction of elongation. In the second archetype the waves exceed the response of the lens border and no equilibrium shape is reached. The lens stretches and eventually breaks into fragments that have a complex dynamics. The difference between the two archetypes is explained by the competition between the radiation pressure the waves exert on the lens border and its response due to surface tension.

  18. Interfaces between Block Copolymer Domains

    Science.gov (United States)

    Kim, Jaeup; Jeong, Seong-Jun; Kim, Sang Ouk

    2011-03-01

    Block copolymers naturally form nanometer scale structures which repeat their geometry on a larger scale. Such a small scale periodic pattern can be used for various applications such as storage media, nano-circuits and optical filters. However, perfect alignment of block copolymer domains in the macroscopic scale is still a distant dream. The nanostructure formation usually occurs with spontaneously broken symmetry; hence it is easily infected by topological defects which sneak in due to entropic fluctuation and incomplete annealing. Careful annealing can gradually reduce the number of defects, but once kinetically trapped, it is extremely difficult to remove all the defects. One of the main reasons is that the defect finds a locally metastable morphology whose potential depth is large enough to prohibit further morphology evolution. In this work, the domain boundaries between differently oriented lamellar structures in thin film are studied. For the first time, it became possible to quantitatively study the block copolymer morphology in the transitional region, and it was shown that the twisted grain boundary is energetically favorable compared to the T-junction grain boundary. [Nano Letters, 9, 2300 (2010)]. This theoretical method successfully explained the experimental results.

  19. Single-domain antibodies for biomedical applications.

    Science.gov (United States)

    Krah, Simon; Schröter, Christian; Zielonka, Stefan; Empting, Martin; Valldorf, Bernhard; Kolmar, Harald

    2016-02-01

    Single-domain antibodies are the smallest antigen-binding units of antibodies, consisting either only of one variable domain or one engineered constant domain that solely facilitates target binding. This class of antibody derivatives comprises naturally occurring variable domains derived from camelids and sharks as well as engineered human variable or constant antibody domains of the heavy or light chain. Because of their high affinity and specificity as well as stability, small size and benefit of multiple re-formatting opportunities, those molecules emerged as promising candidates for biomedical applications and some of these entities have already proven to be successful in clinical development. PMID:26551147

  20. Word Domain Disambiguation via Word Sense Disambiguation

    Energy Technology Data Exchange (ETDEWEB)

    Sanfilippo, Antonio P.; Tratz, Stephen C.; Gregory, Michelle L.

    2006-06-04

    Word subject domains have been widely used to improve the perform-ance of word sense disambiguation al-gorithms. However, comparatively little effort has been devoted so far to the disambiguation of word subject do-mains. The few existing approaches have focused on the development of al-gorithms specific to word domain dis-ambiguation. In this paper we explore an alternative approach where word domain disambiguation is achieved via word sense disambiguation. Our study shows that this approach yields very strong results, suggesting that word domain disambiguation can be ad-dressed in terms of word sense disam-biguation with no need for special purpose algorithms.

  1. Interoperable domain models: The ISO land administration domain model LADM and its external classes

    NARCIS (Netherlands)

    Lemmen, C.H.J.; Van Oosterom, P.J.M.; Uitermark, H.T.; Zevenbergen, J.A.; Cooper, A.K.

    2011-01-01

    This paper provides a brief overview of one of the first spatial domain standards: a standard for the domain of Land Administration (LA). This standard is in the draft stage of development now (May 2011). The development of domain standards is a logical follow up after domain-independent standards,

  2. Chromatin domain boundaries: insulators and beyond

    Institute of Scientific and Technical Information of China (English)

    Gong Hong WEI; De Pei LIU; Chih Chuan LIANG

    2005-01-01

    The eukaryotic genome is organized into functionally and structurally distinct domains, representing regulatory units for gene expression and chromosome behavior. DNA sequences that mark the border between adjacent domains are the insulators or boundary elements, which are required in maintenance of the function of different domains. Some insulators need others enable to play insulation activity. Chromatin domains are defined by distinct sets of post-translationally modified histones. Recent studies show that these histone modifications are also involved in establishment of sharp chromatin boundaries in order to prevent the spreading of distinct domains. Additionally, in some loci, the high-order chromatin structures for long-range looping interactions also have boundary activities, suggesting a correlation between insulators and chromatin loop domains. In this review, we will discuss recent progress in the field of chromatin domain boundaries.

  3. Functional innovation from changes in protein domains and their combinations.

    Science.gov (United States)

    Lees, Jonathan G; Dawson, Natalie L; Sillitoe, Ian; Orengo, Christine A

    2016-06-01

    Domains are the functional building blocks of proteins. In this work we discuss how domains can contribute to the evolution of new functions. Domains themselves can evolve through various mechanisms, altering their intrinsic function. Domains can also facilitate functional innovations by combining with other domains to make novel proteins. We discuss the mechanisms by which domain and domain combinations support functional innovations. We highlight interesting examples where changes in domain combination promote changes at the domain level. PMID:27309309

  4. Structure and Function of KH Domains

    Energy Technology Data Exchange (ETDEWEB)

    Valverde, R.; Regan, E

    2008-01-01

    The hnRNP K homology (KH) domain was first identified in the protein human heterogeneous nuclear ribonucleoprotein K (hnRNP K) 14 years ago. Since then, KH domains have been identified as nucleic acid recognition motifs in proteins that perform a wide range of cellular functions. KH domains bind RNA or ssDNA, and are found in proteins associated with transcriptional and translational regulation, along with other cellular processes. Several diseases, e.g. fragile X mental retardation syndrome and paraneoplastic disease, are associated with the loss of function of a particular KH domain. Here we discuss the progress made towards understanding both general and specific features of the molecular recognition of nucleic acids by KH domains. The typical binding surface of KH domains is a cleft that is versatile but that can typically accommodate only four unpaired bases. Van der Waals forces and hydrophobic interactions and, to a lesser extent, electrostatic interactions, contribute to the nucleic acid binding affinity. 'Augmented' KH domains or multiple copies of KH domains within a protein are two strategies that are used to achieve greater affinity and specificity of nucleic acid binding. Isolated KH domains have been seen to crystallize as monomers, dimers and tetramers, but no published data support the formation of noncovalent higher-order oligomers by KH domains in solution. Much attention has been given in the literature to a conserved hydrophobic residue (typically Ile or Leu) that is present in most KH domains. The interest derives from the observation that an individual with this Ile mutated to Asn, in the KH2 domain of fragile X mental retardation protein, exhibits a particularly severe form of the syndrome. The structural effects of this mutation in the fragile X mental retardation protein KH2 domain have recently been reported. We discuss the use of analogous point mutations at this position in other KH domains to dissect both structure and

  5. Domain-Domain Interactions Underlying Herpesvirus-Human Protein-Protein Interaction Networks

    OpenAIRE

    Zohar Itzhaki

    2011-01-01

    Protein-domains play an important role in mediating protein-protein interactions. Furthermore, the same domain-pairs mediate different interactions in different contexts and in various organisms, and therefore domain-pairs are considered as the building blocks of interactome networks. Here we extend these principles to the host-virus interface and find the domain-pairs that potentially mediate human-herpesvirus interactions. Notably, we find that the same domain-pairs used by other organisms ...

  6. Analysis of DCC domain structure

    International Nuclear Information System (INIS)

    Wavelet-type methods are employed for the analysis of pion field configurations that have been obtained by dynamical simulations in idealized scenarios relevant to the formation of disoriented chiral condensates. It is illustrated how the measurement of the isospin domain structure depends on the ability to zoom in on limited parts of the phase space, due to the interplay between the pion correlation length and the effective source geometry. The need for advanced analysis methods is underscored by the fact that the extracted neutral-fraction distribution would differ significantly from the ideal form, even under perfect experimental conditions, and, moreover, by the circumstance that thermal sources with suitably adjusted temperatures can lead to distributions that may be practically indistinguishable from those arising from DCC-type nonequilibrium evolutions. copyright 1997 The American Physical Society

  7. Listening natively across perceptual domains?

    Science.gov (United States)

    Langus, Alan; Seyed-Allaei, Shima; Uysal, Ertuğrul; Pirmoradian, Sahar; Marino, Caterina; Asaadi, Sina; Eren, Ömer; Toro, Juan M; Peña, Marcela; Bion, Ricardo A H; Nespor, Marina

    2016-07-01

    Our native tongue influences the way we perceive other languages. But does it also determine the way we perceive nonlinguistic sounds? The authors investigated how speakers of Italian, Turkish, and Persian group sequences of syllables, tones, or visual shapes alternating in either frequency or duration. We found strong native listening effects with linguistic stimuli. Speakers of Italian grouped the linguistic stimuli differently from speakers of Turkish and Persian. However, speakers of all languages showed the same perceptual biases when grouping the nonlinguistic auditory and the visual stimuli. The shared perceptual biases appear to be determined by universal grouping principles, and the linguistic differences caused by prosodic differences between the languages. Although previous findings suggest that acquired linguistic knowledge can either enhance or diminish the perception of both linguistic and nonlinguistic auditory stimuli, we found no transfer of native listening effects across auditory domains or perceptual modalities. (PsycINFO Database Record PMID:26820498

  8. Imaging Ferroelectric Domains and Domain Walls Using Charge Gradient Microscopy: Role of Screening Charges.

    Science.gov (United States)

    Tong, Sheng; Jung, Il Woong; Choi, Yoon-Young; Hong, Seungbum; Roelofs, Andreas

    2016-02-23

    Advanced scanning probe microscopies (SPMs) open up the possibilities of the next-generation ferroic devices that utilize both domains and domain walls as active elements. However, current SPMs lack the capability of dynamically monitoring the motion of domains and domain walls in conjunction with the transport of the screening charges that lower the total electrostatic energy of both domains and domain walls. Charge gradient microscopy (CGM) is a strong candidate to overcome these shortcomings because it can map domains and domain walls at high speed and mechanically remove the screening charges. Yet the underlying mechanism of the CGM signals is not fully understood due to the complexity of the electrostatic interactions. Here, we designed a semiconductor-metal CGM tip, which can separate and quantify the ferroelectric domain and domain wall signals by simply changing its scanning direction. Our investigation reveals that the domain wall signals are due to the spatial change of polarization charges, while the domain signals are due to continuous removal and supply of screening charges at the CGM tip. In addition, we observed asymmetric CGM domain currents from the up and down domains, which are originated from the different debonding energies and the amount of the screening charges on positive and negative bound charges. We believe that our findings can help design CGM with high spatial resolution and lead to breakthroughs in information storage and energy-harvesting devices. PMID:26751281

  9. Domains in Ferroic Crystals and Thin Films

    CERN Document Server

    Tagantsev, Alexander K; Fousek, Jan

    2010-01-01

    Domains in Ferroic Crystals and Thin Films presents experimental findings and theoretical understanding of ferroic (non-magnetic) domains developed during the past 60 years. It addresses the situation by looking specifically at bulk crystals and thin films, with a particular focus on recently-developed microelectronic applications and methods for observation of domains with techniques such as scanning force microscopy, polarized light microscopy, scanning optical microscopy, electron microscopy, and surface decorating techniques. Domains in Ferroic Crystals and Thin Films covers a large area of material properties and effects connected with static and dynamic properties of domains, which are extremely relevant to materials referred to as ferroics. In most solid state physics books, one large group of ferroics is customarily covered: those in which magnetic properties play a dominant role. Numerous books are specifically devoted to magnetic ferroics and cover a wide spectrum of magnetic domain phenomena. In co...

  10. A Multipotent Progenitor Domain Guides Pancreatic Organogenesis

    OpenAIRE

    Zhou, Qiao; Law, Anica Chi-Ying; Rajagopal, Jayaraj; Anderson, William J.; Gray, Paul A.; Douglas A Melton

    2007-01-01

    The mammalian pancreas is constructed during embryogenesis by multipotent progenitors, the identity and function of which remain poorly understood. We performed genome-wide transcription factor expression analysis of the developing pancreas to identify gene expression domains that may represent distinct progenitor cell populations. Five discrete domains were discovered. Genetic lineage-tracing experiments demonstrate that one specific domain, located at the tip of the branching pancreatic tre...

  11. A Domain Ontology for Designing Management Services

    OpenAIRE

    Pansa, Ingo; Reichle, Matthias; Leist, Christoph; Abeck, Sebastian

    2014-01-01

    Designing management systems based on serviceoriented principles is a pragmatic approach to handle the challenges that distributed management is faced today. In order to conform to service-oriented principles, the elements of the management systems architecture – the management services – have to be designed along domain-specific concepts. Thus, modeling the domain IT Management becomes evident within service-oriented development processes. Considering existing approaches, domain modeling is ...

  12. Automotion of Domain Walls for Spintronic Interconnects

    OpenAIRE

    Nikonov, Dmitri E.; Manipatruni, Sasikanth; Young, Ian A.

    2013-01-01

    We simulate automotion, the spontaneous transport of a magnetic domain wall under the influence of demagnetization and magnetic anisotropy, in nanoscale spintronic interconnects. In contrast to spin transfer driven magnetic domain wall motion, the proposed interconnects operate with only a transient current pulse and provide favorable scaling down to the 20nm scale. Cases of both in-plane and perpendicular magnetization are considered. Analytical dependence of the velocity of domain walls on ...

  13. Domain shuffling and the evolution of vertebrates

    OpenAIRE

    Kawashima, Takeshi; Kawashima, Shuichi; Tanaka, Chisaki; Murai, Miho; Yoneda, Masahiko; Putnam, Nicholas H.; Rokhsar, Daniel S.; Kanehisa, Minoru; Satoh, Nori; Wada, Hiroshi

    2009-01-01

    The evolution of vertebrates has included a number of important events: the development of cartilage, the immune system, and complicated craniofacial structures. Here, we examine domain shuffling as one of the mechanisms that contributes novel genetic material required for vertebrate evolution. We mapped domain-shuffling events during the evolution of deuterostomes with a focus on how domain shuffling contributed to the evolution of vertebrate- and chordate-specific characteristics. We identi...

  14. Two-Domain DNA Strand Displacement

    OpenAIRE

    Luca Cardelli

    2010-01-01

    We investigate the computing power of a restricted class of DNA strand displacement structures: those that are made of double strands with nicks (interruptions) in the top strand. To preserve this structural invariant, we impose restrictions on the single strands they interact with: we consider only two-domain single strands consisting of one toehold domain and one recognition domain. We study fork and join signal-processing gates based on these structures, and we show that these systems are ...

  15. Homogenization of eigenvalue problems in perforated domains

    OpenAIRE

    Vanninathan, M.

    1981-01-01

    In this paper, we treat some eigenvalue problems in periodically perforated domains and study the asymptotic behaviour of the eigenvalues and the eigenvectors when the number of holes in the domain increases to infinity Using the method of asymptotic expansion, we give explicit formula for the homogenized coefficients and expansion for eigenvalues and eigenvectors. If we denote by ε the size of each hole in the domain, then we obtain the following aysmptotic expansion for the eigenvalues: Dir...

  16. Charm physics with Moebius Domain Wall Fermions

    CERN Document Server

    Jüttner, Andreas; Tsang, Justus Tobias; Boyle, Peter; Marinkovic, Marina; Hashimoto, Shoji; Kaneko, Takashi; Cho, Yong-Gwi

    2015-01-01

    We present results showing that Domain Wall fermions are a suitable discretisation for the simulation of heavy quarks. This is done by a continuum scaling study of charm quarks in a M\\"obius Domain Wall formalism using a quenched set-up. We find that discretisation effects remain well controlled by the choice of Domain Wall parameters preparing the ground work for the ongoing dynamical $2+1f$ charm program of RBC/UKQCD.

  17. Domain transformations for optical telecommunications signals

    OpenAIRE

    Ng, Trina Tsao-Tin

    2010-01-01

    In this thesis, the transformation of optical telecommunication signal waveforms between the temporal and spectral domains is investigated. Temporal optical Fourier transformations (TOFTs) are presented with the primary aim of mitigating distortions in high repetition rate telecommunication signals, by transferring them from the temporal domain into the frequency domain. Development of TOFT is extended to aid their suitability for other applications also. The TOFT is based on inducing cro...

  18. Spread spectrum time domain reflectometry

    Science.gov (United States)

    Smith, Paul Samuel

    For many years, wiring has been treated as a system that could be installed and expected to work for the life of the aircraft. As aircraft age far beyond their original expected life span, this attitude is rapidly changing. Wiring problems have recently been identified as the cause of several tragic mishaps and hundreds of thousands of lost mission hours. Intermittent wiring faults have been and continue to be difficult to resolve. Test methods that pinpoint faults on the ground can miss intermittent failures. New test methods involving spread spectrum signals are investigated that could be used in flight to locate intermittent failures, including open circuits, short circuits, and arcs. Spread spectrum time domain reflectometry (SSTDR) and sequence time domain reflectometry (STDR) are analyzed in light of the signals commonly present on aircraft wiring. Pseudo noise codes used for the generation of STDR and SSTDR signals are analyzed for application in a STDR/SSTDR test system in the presence of noise. The effects of Mil-Std 1553 and white noise on the STDR and SSTDR signals are discussed analytically, through simulations, and with the use of test hardware. A test system using STDR and SSTDR is designed, built, and used to collect STDR and SSTDR test data. The data collected with the STDR/SSTDR test hardware is analyzed and compared to the theoretical results. Experimental data for open and short circuits collected using SSTDR and a curve fitting algorithm shows a maximum range estimation error of +/-0.2 ft for 75O coaxial cable up to 100ft, and +/-0.6ft for a sample 32.5ft non-controlled impedance aircraft cable. Mil-Std 1553 is specified to operate reliably with a signal-to-noise ratio of 17.5dB, and the SSTDR test system was able to locate an open circuit on a cable also carrying simulated Mil-Std 1553 data where the SSTDR signal was 50dB below the Mil-Std 1553 signal. STDR and SSTDR are shown to be effective in detecting and locating dry and wet arcs on wires.

  19. SARS Coronavirus-unique Domain (SUD): Three-domain Molecular Architecture in Solution and RNA Binding

    OpenAIRE

    Johnson, Margaret A.; Chatterjee, Amarnath; Neuman, Benjamin W.; Wüthrich, Kurt

    2010-01-01

    The nonstructural protein 3 (nsp3) of the severe acute respiratory syndrome coronavirus (SARS-CoV) includes a “SARS-unique region” (SUD) consisting of three globular domains separated by short linker peptide segments. This paper reports NMR structure determinations of the C-terminal domain (SUD-C) and of a two-domain construct (SUD-MC) containing the middle domain (SUD-M) and the C-terminal domain, and NMR data on the conformational states of the N-terminal domain (SUD-N) and the SUD-NM two-d...

  20. LSH Ensemble: Internet Scale Domain Search

    OpenAIRE

    Zhu, Erkang; Nargesian, Fatemeh; Pu, Ken Q.; Miller, Renée J.

    2016-01-01

    We study the problem of domain search where a domain is a set of values from an unspecified universe. We use set containment, defined as $|Q \\cap X|/|Q|$, as the measure of relevance of a domain $X$ to a query domain $Q$. Our choice of set containment over Jaccard similarity as a measure of relevance makes our work particularly suitable for searching Open Data and data on the web, as Jaccard similarity is known to have poor performance over sets with large differences in their sizes. We demon...

  1. A new method for extracting domain terminology

    Institute of Scientific and Technical Information of China (English)

    PEI Bing-zhen; CHEN Xiao-rong; HU Yi; LU Ru-zhan

    2009-01-01

    This article proposes a new general, highly efficient algorithm for extracting domain terminologies.This domain-independent algorithm with multi-layers of filters is a hybrid of statistic-oriented and rule-oriented methods. Utilizing the features of domain terminologies and the characteristics that are unique to Chinese, this algorithm extracts domain terminologies by generating multi-word unit (MWU) candidates at first and then filtering the candidates through multi-strategies. Our test results show that this algorithm is feasible and effective.

  2. Multiple graph regularized protein domain ranking

    Directory of Open Access Journals (Sweden)

    Wang Jim

    2012-11-01

    Full Text Available Abstract Background Protein domain ranking is a fundamental task in structural biology. Most protein domain ranking methods rely on the pairwise comparison of protein domains while neglecting the global manifold structure of the protein domain database. Recently, graph regularized ranking that exploits the global structure of the graph defined by the pairwise similarities has been proposed. However, the existing graph regularized ranking methods are very sensitive to the choice of the graph model and parameters, and this remains a difficult problem for most of the protein domain ranking methods. Results To tackle this problem, we have developed the Multiple Graph regularized Ranking algorithm, MultiG-Rank. Instead of using a single graph to regularize the ranking scores, MultiG-Rank approximates the intrinsic manifold of protein domain distribution by combining multiple initial graphs for the regularization. Graph weights are learned with ranking scores jointly and automatically, by alternately minimizing an objective function in an iterative algorithm. Experimental results on a subset of the ASTRAL SCOP protein domain database demonstrate that MultiG-Rank achieves a better ranking performance than single graph regularized ranking methods and pairwise similarity based ranking methods. Conclusion The problem of graph model and parameter selection in graph regularized protein domain ranking can be solved effectively by combining multiple graphs. This aspect of generalization introduces a new frontier in applying multiple graphs to solving protein domain ranking applications.

  3. Domain wall resistance in epitaxial Fe wires

    Energy Technology Data Exchange (ETDEWEB)

    Hassel, C., E-mail: christoph.hassel@uni-due.d [Fachbereich Physik and Center for Nanointegration Duisburg-Essen (CeNIDE), Universitaet Duisburg-Essen, 47048 Duisburg (Germany); Roemer, F.M.; Reckers, N. [Fachbereich Physik and Center for Nanointegration Duisburg-Essen (CeNIDE), Universitaet Duisburg-Essen, 47048 Duisburg (Germany); Kronast, F. [Bessy GmbH, Berlin (Germany); Dumpich, G.; Lindner, J. [Fachbereich Physik and Center for Nanointegration Duisburg-Essen (CeNIDE), Universitaet Duisburg-Essen, 47048 Duisburg (Germany)

    2011-04-15

    We studied the magnetoresistance behavior of epitaxial Fe wires grown on GaAs(1 1 0) with varying widths at room temperature. Single nanowires show a wire width (w) dependence of the coercive field, which increases with 1/w for decreasing wire widths. This enables the pinning of a single domain wall in the connection area of two wires with different widths. Magnetoresistance measurements of such wire structures clearly reveal resistance contributions arising from a domain wall. The presence of the domain wall is proven by photoemission electron-microscopy with synchrotron radiation. Moreover, micromagnetic simulations are performed to determine the spin orientations, especially within the domain wall. This permits us to calculate the anisotropic magnetoresistance caused by the domain wall. Taking this into account, we determine the intrinsic domain wall resistance, for which we found a positive value of 0.2%, in agreement with theoretical predictions. - Research highlights: > Magnetoresistance of epitaxial Fe wires is studied. > Pinning of a single domain wall at constriction. > Detection of domain wall by resistance and XPEEM measurements. > AMR contribution calculated by micromagnetic simulations. > Positive intrinsic domain wall resistance in agreement with theory.

  4. Domain wall resistance in epitaxial Fe wires

    International Nuclear Information System (INIS)

    We studied the magnetoresistance behavior of epitaxial Fe wires grown on GaAs(1 1 0) with varying widths at room temperature. Single nanowires show a wire width (w) dependence of the coercive field, which increases with 1/w for decreasing wire widths. This enables the pinning of a single domain wall in the connection area of two wires with different widths. Magnetoresistance measurements of such wire structures clearly reveal resistance contributions arising from a domain wall. The presence of the domain wall is proven by photoemission electron-microscopy with synchrotron radiation. Moreover, micromagnetic simulations are performed to determine the spin orientations, especially within the domain wall. This permits us to calculate the anisotropic magnetoresistance caused by the domain wall. Taking this into account, we determine the intrinsic domain wall resistance, for which we found a positive value of 0.2%, in agreement with theoretical predictions. - Research highlights: → Magnetoresistance of epitaxial Fe wires is studied. → Pinning of a single domain wall at constriction. → Detection of domain wall by resistance and XPEEM measurements. → AMR contribution calculated by micromagnetic simulations. → Positive intrinsic domain wall resistance in agreement with theory.

  5. TWO STAGE SPATIAL DOMAIN IMAGE FUSION TECHNIQUES

    Directory of Open Access Journals (Sweden)

    C. Morris

    2014-08-01

    Full Text Available The objective of Image fusion is to combine the information from number of images of the same scene from different sensors or the images with focus on different objects. The result of image fusion is an image which is more informative and of better quality. In this paper a detailed survey of Select Maximum /minimum and principal component analysis for spatial domain image fusion techniques is done. On the basis of the survey an improved spatial domain fusion technique is proposed. The proposed spatial domain technique output performs as the state of the art spatial domain techniques.

  6. Multiple graph regularized protein domain ranking

    KAUST Repository

    Wang, Jim Jing-Yan

    2012-11-19

    Background: Protein domain ranking is a fundamental task in structural biology. Most protein domain ranking methods rely on the pairwise comparison of protein domains while neglecting the global manifold structure of the protein domain database. Recently, graph regularized ranking that exploits the global structure of the graph defined by the pairwise similarities has been proposed. However, the existing graph regularized ranking methods are very sensitive to the choice of the graph model and parameters, and this remains a difficult problem for most of the protein domain ranking methods.Results: To tackle this problem, we have developed the Multiple Graph regularized Ranking algorithm, MultiG-Rank. Instead of using a single graph to regularize the ranking scores, MultiG-Rank approximates the intrinsic manifold of protein domain distribution by combining multiple initial graphs for the regularization. Graph weights are learned with ranking scores jointly and automatically, by alternately minimizing an objective function in an iterative algorithm. Experimental results on a subset of the ASTRAL SCOP protein domain database demonstrate that MultiG-Rank achieves a better ranking performance than single graph regularized ranking methods and pairwise similarity based ranking methods.Conclusion: The problem of graph model and parameter selection in graph regularized protein domain ranking can be solved effectively by combining multiple graphs. This aspect of generalization introduces a new frontier in applying multiple graphs to solving protein domain ranking applications. 2012 Wang et al; licensee BioMed Central Ltd.

  7. The All-DQ-Domain EMTP

    OpenAIRE

    Gibson H.M. Sianipar

    2011-01-01

    This paper presents an improvement to dq-domain method of calculating electromagnetic transients. The proposed methodology works on dq-domain model for all components of the power system and during all time iterations. This is a new direction distinct from the old one where the network is invariably modeled in phase-domain. By modeling the network in dq-domain there is no more problem of interfacing machine to network as usually met in the existing method as machine is modeled invariably in ...

  8. Cooperative interactions between paired domain and homeodomain.

    Science.gov (United States)

    Jun, S; Desplan, C

    1996-09-01

    The Pax proteins are a family of transcriptional regulators involved in many developmental processes in all higher eukaryotes. They are characterized by the presence of a paired domain (PD), a bipartite DNA binding domain composed of two helix-turn-helix (HTH) motifs,the PAI and RED domains. The PD is also often associated with a homeodomain (HD) which is itself able to form homo- and hetero-dimers on DNA. Many of these proteins therefore contain three HTH motifs each able to recognize DNA. However, all PDs recognize highly related DNA sequences, and most HDs also recognize almost identical sites. We show here that different Pax proteins use multiple combinations of their HTHs to recognize several types of target sites. For instance, the Drosophila Paired protein can bind, in vitro, exclusively through its PAI domain, or through a dimer of its HD, or through cooperative interaction between PAI domain and HD. However, prd function in vivo requires the synergistic action of both the PAI domain and the HD. Pax proteins with only a PD appear to require both PAI and RED domains, while a Pax-6 isoform and a new Pax protein, Lune, may rely on the RED domain and HD. We propose a model by which Pax proteins recognize different target genes in vivo through various combinations of their DNA binding domains, thus expanding their recognition repertoire. PMID:8787739

  9. Electrons in ferromagnets with domain walls

    International Nuclear Information System (INIS)

    Domain walls can significantly modify electronic properties of ferromagnetic metals. In this paper we consider theoretically the influence of domain walls on transport properties of ferromagnetic materials and the results are compared with recent experiments. In the case of diffusive transport through a thick domain wall, the semiclassical approximation is applied and a local spin transformation is performed, which replaces the system with a domain wall by the corresponding system without a domain wall but with an additional gauge field. Due to a redistribution of single-particle electron states at the wall, one obtains then either negative or positive contributions to resistivity. The situation is different for very narrow and/or constrained domain walls. In such a case, the semiclassical approximation is not valid. Instead of this the approach based on scattering matrix is applied. The domain wall then gives rise to a large positive contribution to electrical resistivity. The corresponding magnetoresistance can be therefore very large, which is in agreement with recent experiments. The limiting case of narrow domain walls in systems with a single conduction channel is analysed in detail, with the effects due to electron-electron interaction taken into account. In this particular case the magnetoresistance due to a domain wall can be extremely large

  10. Renormalization group domains of the scalar Hamiltonian

    OpenAIRE

    Bagnuls, C.; Bervillier, C.

    2000-01-01

    Using the local potential approximation of the exact renormalization group (RG) equation, we show the various domains of values of the parameters of the O(1)-symmetric scalar Hamiltonian. In three dimensions, in addition to the usual critical surface $S_{c}$ (attraction domain of the Wilson-Fisher fixed point), we explicitly show the existence of a first-order phase transition domain $S_{f}$ separated from $S_{c}$ by the tricritical surface $S_{t}$ (attraction domain of the Gaussian fixed poi...

  11. Transform domain steganography with blind source separation

    Science.gov (United States)

    Jouny, Ismail

    2015-05-01

    This paper applies blind source separation or independent component analysis for images that may contain mixtures of text, audio, or other images for steganography purposes. The paper focuses on separating mixtures in the transform domain such as Fourier domain or the Wavelet domain. The study addresses the effectiveness of steganography when using linear mixtures of multimedia components and the ability of standard blind sources separation techniques to discern hidden multimedia messages. Mixing in the space, frequency, and wavelet (scale) domains is compared. Effectiveness is measured using mean square error rate between original and recovered images.

  12. The Private Legal Governance of Domain Names

    DEFF Research Database (Denmark)

    Schovsbo, Jens Hemmingsen

    2015-01-01

    UDRP (WIPO) and the Danish Complaints Board for Internet Domain Names (the Board) to discuss how and to what extent the domain name system balances interests between trademark owners and other users of domain names and secures the rule of law (legal certainty and predictability) with a special focus on...... cases where trademarks are used as (parts of) domain names to express criticism of the trademark holder or the trademark itself (e.g. “TMsucks.com” / “lorteTM.dk”). The article is part of a research project on “User Generated Law” and uses the methodologies developed as part of this. It is scheduled to...

  13. Discoidin domain receptors in disease.

    Science.gov (United States)

    Borza, Corina M; Pozzi, Ambra

    2014-02-01

    Discoidin domain receptors, DDR1 and DDR2, lie at the intersection of two large receptor families, namely the extracellular matrix and tyrosine kinase receptors. As such, DDRs are uniquely positioned to function as sensors for extracellular matrix and to regulate a wide range of cell functions from migration and proliferation to cytokine secretion and extracellular matrix homeostasis/remodeling. While activation of DDRs by extracellular matrix collagens is required for normal development and tissue homeostasis, aberrant activation of these receptors following injury or in disease is detrimental. The availability of mice lacking DDRs has enabled us to identify key roles played by these receptors in disease initiation and progression. DDR1 promotes inflammation in atherosclerosis, lung fibrosis and kidney injury, while DDR2 contributes to osteoarthritis. Furthermore, both DDRs have been implicated in cancer progression. Yet the mechanisms whereby DDRs contribute to disease progression are poorly understood. In this review we highlight the mechanisms whereby DDRs regulate two important processes, namely inflammation and tissue fibrosis. In addition, we discuss the challenges of targeting DDRs in disease. Selective targeting of these receptors requires understanding of how they interact with and are activated by extracellular matrix, and whether their cellular function is dependent on or independent of receptor kinase activity. PMID:24361528

  14. Public domain optical character recognition

    Science.gov (United States)

    Garris, Michael D.; Blue, James L.; Candela, Gerald T.; Dimmick, Darrin L.; Geist, Jon C.; Grother, Patrick J.; Janet, Stanley A.; Wilson, Charles L.

    1995-03-01

    A public domain document processing system has been developed by the National Institute of Standards and Technology (NIST). The system is a standard reference form-based handprint recognition system for evaluating optical character recognition (OCR), and it is intended to provide a baseline of performance on an open application. The system's source code, training data, performance assessment tools, and type of forms processed are all publicly available. The system recognizes the handprint entered on handwriting sample forms like the ones distributed with NIST Special Database 1. From these forms, the system reads hand-printed numeric fields, upper and lowercase alphabetic fields, and unconstrained text paragraphs comprised of words from a limited-size dictionary. The modular design of the system makes it useful for component evaluation and comparison, training and testing set validation, and multiple system voting schemes. The system contains a number of significant contributions to OCR technology, including an optimized probabilistic neural network (PNN) classifier that operates a factor of 20 times faster than traditional software implementations of the algorithm. The source code for the recognition system is written in C and is organized into 11 libraries. In all, there are approximately 19,000 lines of code supporting more than 550 subroutines. Source code is provided for form registration, form removal, field isolation, field segmentation, character normalization, feature extraction, character classification, and dictionary-based postprocessing. The recognition system has been successfully compiled and tested on a host of UNIX workstations. This paper gives an overview of the recognition system's software architecture, including descriptions of the various system components along with timing and accuracy statistics.

  15. Domain wall fermions in vector gauge theories

    OpenAIRE

    Blum, T.

    1998-01-01

    I review domain wall fermions in vector gauge theories. Following a brief introduction, the status of lattice calculations using domain wall fermions is presented. I focus on results from QCD, including the light quark masses and spectrum, weak matrix elements, the $n_f=2$ finite temperature phase transition, and topology and zero modes and conclude with topics for future study.

  16. Frequency domain image filtering using cuda

    International Nuclear Information System (INIS)

    In this paper, we investigate the implementation of image filtering in frequency domain using NVIDIA's CUDA (Compute Unified Device Architecture). In contrast to signal and image filtering in spatial domain which uses convolution operations and hence is more compute-intensive for filters having larger spatial extent, the frequency domain filtering uses FFT (Fast Fourier Transform) which is much faster and significantly reduces the computational complexity of the filtering. We implement the frequency domain filtering on CPU and GPU respectively and analyze the speed-up obtained from the CUDA's parallel processing paradigm. In order to demonstrate the efficiency of frequency domain filtering on CUDA, we implement three frequency domain filters, i.e., Butter worth, low-pass and Gaussian for processing different sizes of images on CPU and GPU respectively and perform the GPU vs. CPU benchmarks. The results presented in this paper show that the frequency domain filtering with CUDA achieves significant speed-up over the CPU processing in frequency domain with the same level of (output) image quality on both the processing architectures. (author)

  17. Hydrogels with Micellar Hydrophobic (Nano)Domains

    OpenAIRE

    Pekař, Miloslav

    2015-01-01

    Hydrogels containing hydrophobic domains or nanodomains, especially of the micellar type, are reviewed. Examples of the reasons for introducing hydrophobic domains into hydrophilic gels are given; typology of these materials is introduced. Synthesis routes are exemplified and properties of a variety of such hydrogels in relation with their intended applications are described. Future research needs are identified briefly.

  18. Frequency Domain Image Filtering Using CUDA

    Directory of Open Access Journals (Sweden)

    Muhammad Awais Rajput

    2014-10-01

    Full Text Available In this paper, we investigate the implementation of image filtering in frequency domain using NVIDIA?s CUDA (Compute Unified Device Architecture. In contrast to signal and image filtering in spatial domain which uses convolution operations and hence is more compute-intensive for filters having larger spatial extent, the frequency domain filtering uses FFT (Fast Fourier Transform which is much faster and significantly reduces the computational complexity of the filtering. We implement the frequency domain filtering on CPU and GPU respectively and analyze the speed-up obtained from the CUDA?s parallel processing paradigm. In order to demonstrate the efficiency of frequency domain filtering on CUDA, we implement three frequency domain filters, i.e., Butterworth, low-pass and Gaussian for processing different sizes of images on CPU and GPU respectively and perform the GPU vs. CPU benchmarks. The results presented in this paper show that the frequency domain filtering with CUDA achieves significant speed-up over the CPU processing in frequency domain with the same level of (output image quality on both the processing architectures

  19. A Characterization of Complete Bounded Domain

    Institute of Scientific and Technical Information of China (English)

    殷慰萍; 苏简兵; 赵振刚

    2002-01-01

    @@ 1 IntroductionThis paper is concerned with biholomorphic mappings between two bounded domains D and G both in Cn.Consequently,an important question is whether the domain D is biholomorphic to G? We give an answer for this question under a very weak condition.

  20. Multilevel domain decomposition for electronic structure calculations

    CERN Document Server

    Barrault, M; Hager, W W; Le Bris, C

    2005-01-01

    We introduce a new multilevel domain decomposition method (MDD) for electronic structure calculations within semi-empirical and Density Functional Theory (DFT) frameworks. This method iterates between local fine solvers and global coarse solvers, in the spirit of domain decomposition methods.

  1. Automotion of domain walls for spintronic interconnects

    Science.gov (United States)

    Nikonov, Dmitri E.; Manipatruni, Sasikanth; Young, Ian A.

    2014-06-01

    We simulate "automotion," the transport of a magnetic domain wall under the influence of demagnetization and magnetic anisotropy, in nanoscale spintronic interconnects. In contrast to spin transfer driven magnetic domain wall motion, the proposed interconnects operate without longitudinal charge current transfer, with only a transient current pulse at domain wall creation and have favorable scaling down to the 20 nm dimension. Cases of both in-plane and out-of-plane magnetization are considered. Analytical dependence of the velocity of domain walls on the angle of magnetization are compared with full micromagnetic simulations. Deceleration, attenuation and disappearance, and reflection of domain walls are demonstrated through simulation. Dependences of the magnetization angle on the current pulse parameters are studied. The energy and delay analysis suggests that automotion is an attractive option for spintronic logic interconnects.

  2. Automotion of domain walls for spintronic interconnects

    International Nuclear Information System (INIS)

    We simulate “automotion,” the transport of a magnetic domain wall under the influence of demagnetization and magnetic anisotropy, in nanoscale spintronic interconnects. In contrast to spin transfer driven magnetic domain wall motion, the proposed interconnects operate without longitudinal charge current transfer, with only a transient current pulse at domain wall creation and have favorable scaling down to the 20 nm dimension. Cases of both in-plane and out-of-plane magnetization are considered. Analytical dependence of the velocity of domain walls on the angle of magnetization are compared with full micromagnetic simulations. Deceleration, attenuation and disappearance, and reflection of domain walls are demonstrated through simulation. Dependences of the magnetization angle on the current pulse parameters are studied. The energy and delay analysis suggests that automotion is an attractive option for spintronic logic interconnects.

  3. Automotion of domain walls for spintronic interconnects

    Energy Technology Data Exchange (ETDEWEB)

    Nikonov, Dmitri E.; Manipatruni, Sasikanth; Young, Ian A. [Exploratory Integrated Circuits, Components Research, Intel Corp., Hillsboro, Oregon 97124 (United States)

    2014-06-07

    We simulate “automotion,” the transport of a magnetic domain wall under the influence of demagnetization and magnetic anisotropy, in nanoscale spintronic interconnects. In contrast to spin transfer driven magnetic domain wall motion, the proposed interconnects operate without longitudinal charge current transfer, with only a transient current pulse at domain wall creation and have favorable scaling down to the 20 nm dimension. Cases of both in-plane and out-of-plane magnetization are considered. Analytical dependence of the velocity of domain walls on the angle of magnetization are compared with full micromagnetic simulations. Deceleration, attenuation and disappearance, and reflection of domain walls are demonstrated through simulation. Dependences of the magnetization angle on the current pulse parameters are studied. The energy and delay analysis suggests that automotion is an attractive option for spintronic logic interconnects.

  4. Requirements analysis, domain knowledge, and design

    Science.gov (United States)

    Potts, Colin

    1988-01-01

    Two improvements to current requirements analysis practices are suggested: domain modeling, and the systematic application of analysis heuristics. Domain modeling is the representation of relevant application knowledge prior to requirements specification. Artificial intelligence techniques may eventually be applicable for domain modeling. In the short term, however, restricted domain modeling techniques, such as that in JSD, will still be of practical benefit. Analysis heuristics are standard patterns of reasoning about the requirements. They usually generate questions of clarification or issues relating to completeness. Analysis heuristics can be represented and therefore systematically applied in an issue-based framework. This is illustrated by an issue-based analysis of JSD's domain modeling and functional specification heuristics. They are discussed in the context of the preliminary design of simple embedded systems.

  5. RG Domain Walls and Hybrid Triangulations

    CERN Document Server

    Dimofte, Tudor; van der Veen, Roland

    2013-01-01

    This paper studies the interplay between the N=2 gauge theories in three and four dimensions that have a geometric description in terms of twisted compactification of the six-dimensional (2,0) SCFT. Our main goal is to construct the three-dimensional domain walls associated to any three-dimensional cobordism. We find that we can build a variety of 3d theories that represent the local degrees of freedom at a given domain wall in various 4d duality frames, including both UV S-dual frames and IR Seiberg-Witten electric-magnetic dual frames. We pay special attention to Janus domain walls, defined by four-dimensional Lagrangians with position-dependent couplings. If the couplings on either side of the wall are weak in different UV duality frames, Janus domain walls reduce to S-duality walls, i.e. domain walls that encode the properties of UV dualities. If the couplings on one side are weak in the IR and on the other weak in the UV, Janus domain walls reduce to RG walls, i.e. domain walls that encode the properties...

  6. Insights into function of PSI domains from structure of the Met receptor PSI domain

    International Nuclear Information System (INIS)

    PSI domains are cysteine-rich modules found in extracellular fragments of hundreds of signaling proteins, including plexins, semaphorins, integrins, and attractins. Here, we report the solution structure of the PSI domain from the human Met receptor, a receptor tyrosine kinase critical for proliferation, motility, and differentiation. The structure represents a cysteine knot with short regions of secondary structure including a three-stranded antiparallel β-sheet and two α-helices. All eight cysteines are involved in disulfide bonds with the pattern consistent with that for the PSI domain from Sema4D. Comparison with the Sema4D structure identifies a structurally conserved core comprising the N-terminal half of the PSI domain. Interestingly, this part links adjacent SEMA and immunoglobulin domains in the Sema4D structure, suggesting that the PSI domain serves as a wedge between propeller and immunoglobulin domains and is responsible for the correct positioning of the ligand-binding site of the receptor

  7. Quasiparticles near domain walls in hexagonal superconductors

    Science.gov (United States)

    Mukherjee, S. P.; Samokhin, K. V.

    2016-02-01

    We calculate the energy spectrum of quasiparticles trapped by a domain wall separating different time-reversal symmetry-breaking ground states in a hexagonal superconductor, such as UPt3. The bound-state energy is found to be strongly dependent on the gap symmetry, the domain-wall orientation, the quasiparticle's direction of semiclassical propagation, and the phase difference between the domains. We calculate the corresponding density of states and show how one can use its prominent features, in particular, the zero-energy singularity, to distinguish between different pairing symmetries.

  8. Domain structure of circular and ring magnets

    International Nuclear Information System (INIS)

    We present the results of a study of the domain structure and the magnetization reversal processes in arrays of circular and ring magnets, obtained by magnetic force microscopy and magnetization measurements. The particles, with outer diameter 0.55 and 2.2 μm, were made of Permalloy films of thickness 24 and 66 nm. In the circular elements two domain configurations were observed: a vortex structure with perpendicular magnetization at the core and a 'bud' state. In the ring elements the domain structure was found to depend on the ring width: a flux closed state was formed in wide rings and the 'onion' state was observed in narrow rings

  9. Domain Driven Data Mining - Application to Business

    Directory of Open Access Journals (Sweden)

    Adeyemi Adejuwon

    2010-07-01

    Full Text Available Conventional data mining applications face serious difficulties in solving complex real-life business decision making problems when practically deployed. This work in order to improve the operations in a collection of business domains aims to suggest solutions by reviewing and studying the latest methodological, technical, practical progresses and some cases studies of data mining via domain driven data mining (DDDM. The presented paper tries to answer this question: "what can domain driven data mining do for real-life business applications?" Moreover this work attempts to provide information and abilities to fill the existing gap between academic researches and real-world business problems.

  10. UBA domain containing proteins in fission yeast

    DEFF Research Database (Denmark)

    Hartmann-Petersen, Rasmus; Semple, Colin A M; Ponting, Chris P;

    2003-01-01

    and transcription. Considering this variety of cell biological processes, it is puzzling that until recently only very few proteins were known to possess the ability to interact specifically with ubiquitin chains. However, several ubiquitin binding proteins have now been identified and the binding domains have been...... characterised on both the functional and structural levels. One example of a widespread ubiquitin binding module is the ubiquitin associated (UBA) domain. Here, we discuss the approximately 15 UBA domain containing proteins encoded in the relatively small genome of the fission yeast Schizosaccharomyces pombe...

  11. Two-Domain DNA Strand Displacement

    Directory of Open Access Journals (Sweden)

    Luca Cardelli

    2010-06-01

    Full Text Available We investigate the computing power of a restricted class of DNA strand displacement structures: those that are made of double strands with nicks (interruptions in the top strand. To preserve this structural invariant, we impose restrictions on the single strands they interact with: we consider only two-domain single strands consisting of one toehold domain and one recognition domain. We study fork and join signal-processing gates based on these structures, and we show that these systems are amenable to formalization and to mechanical verification.

  12. Two-Domain DNA Strand Displacement

    CERN Document Server

    Cardelli, Luca

    2010-01-01

    We investigate the computing power of a restricted class of DNA strand displacement structures: those that are made of double strands with nicks (interruptions) in the top strand. To preserve this structural invariant, we impose restrictions on the single strands they interact with: we consider only two-domain single strands consisting of one toehold domain and one recognition domain. We study fork and join signal-processing gates based on these structures, and we show that these systems are amenable to formalization and to mechanical verification.

  13. System Identification A Frequency Domain Approach

    CERN Document Server

    Pintelon, Rik

    2012-01-01

    System identification is a general term used to describe mathematical tools and algorithms that build dynamical models from measured data. Used for prediction, control, physical interpretation, and the designing of any electrical systems, they are vital in the fields of electrical, mechanical, civil, and chemical engineering. Focusing mainly on frequency domain techniques, System Identification: A Frequency Domain Approach, Second Edition also studies in detail the similarities and differences with the classical time domain approach. It high??lights many of the important steps in the identi

  14. Characterization of domain reorientation in Pzt ceramics

    International Nuclear Information System (INIS)

    The dynamic of domains in ferroelectric materials has been intensively studied due to its importance in applications like non volatile memories. Domain reorientation was characterized in lead zirconate titanate samples, pure and doped, through measurements of the transient current, after reversal a electric field. The reorientation behavior of the domains showed to be influenced by type of impurity (Nb or Fe) and by the electrical field intensity. Analysis of the experimental results reveals mainly the existence of two contributions: a dependent (t 0.1 s) of the field intensity. (author)

  15. Domain-decomposed preconditionings for transport operators

    Science.gov (United States)

    Chan, Tony F.; Gropp, William D.; Keyes, David E.

    1991-01-01

    The performance was tested of five different interface preconditionings for domain decomposed convection diffusion problems, including a novel one known as the spectral probe, while varying mesh parameters, Reynolds number, ratio of subdomain diffusion coefficients, and domain aspect ratio. The preconditioners are representative of the range of practically computable possibilities that have appeared in the domain decomposition literature for the treatment of nonoverlapping subdomains. It is shown that through a large number of numerical examples that no single preconditioner can be considered uniformly superior or uniformly inferior to the rest, but that knowledge of particulars, including the shape and strength of the convection, is important in selecting among them in a given problem.

  16. Image domain propeller fast spin echo☆

    OpenAIRE

    Skare, Stefan; Holdsworth, Samantha J.; Lilja, Anders; Bammer, Roland

    2012-01-01

    A new pulse sequence for high-resolution T2-weighted (T2-w) imaging is proposed –image domain propeller fast spin echo (iProp-FSE). Similar to the T2-w PROPELLER sequence, iProp-FSE acquires data in a segmented fashion, as blades that are acquired in multiple TRs. However, the iProp-FSE blades are formed in the image domain instead of in the k-space domain. Each iProp-FSE blade resembles a single-shot fast spin echo (SSFSE) sequence with a very narrow phase-encoding field of view (FOV), after...

  17. Indices of Toeplitz tuples on pseudoregular domains

    Institute of Scientific and Technical Information of China (English)

    郭坤宇

    2000-01-01

    This paper proves an index theorem of Toeplitz tuples on pseudoregular domains in Cn. Geometrically, the index of Toeplitz tuple T n is ( -1)n time wrapping number of n around the origin. As one of the applications of the index theorem, we completely characterize the automorphism groups of Toeplitz algebras on Poincare domain. As another application, it is shown that C* (Ω) ≌ C* ( Bn) for every Poincare domain Ω in Cn( n≠2). It is also noticed that C* (Ω) ≌ C* ( B2) if and only if the Poincaré conjecture is true for Ω.

  18. Indices of Toeplitz tuples on pseudoregular domains

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    This paper proves an index theorem of Toeplitz tuples on pseudoregular domains in Cn. Geometrically, the index of Toeplitz tuple TΦn is (-1)n time wrapping number of Φn around the origin. As one of the applications of the index theorem, we completely characterize the automorphism groups of Toeplitz algebras on Poincaré domain. As another application, it is shown that C*(Ω)C*(Bn) for every Poincare domain Ω in Cn(n≠2). It is also noticed that C*(Ω)C*(B2) if and only if the Poincaré conjecture is true for Ω.

  19. Photonic crystal biosensor in spatial fourier domain

    OpenAIRE

    Hallynck, Elewout; Bienstman, Peter

    2011-01-01

    We propose a photonic crystal biosensor, operating at a single wavelength, based on analysis of resonant guided modes in the spatial Fourier domain. Sensitivities of 65 degrees per RIU and more have been simulated.

  20. Patient Centric Ontology for Telehealth Domain

    DEFF Research Database (Denmark)

    Jørgensen, Daniel Bjerring; Hallenborg, Kasper; Demazeau, Yves

    2015-01-01

    This paper presents an ontology for the telehealth domain, a domain that concerns the use of telecommunication to support and deliver health related services e.g. patient monitoring and rehabilitative training. Our vision for the future of telehealth solutions is that they adapt their behavior...... to the needs, habits, and personality of the patient through user modeling and context awareness. The ontology will be our foundation for user modeling of patients in the telehealth domain, and hence it is one of the initial steps toward our vision. Compared to other ontologies within the domain, ours has...... with external systems. Besides being the foundation for user modeling, the ontology is a component in the Patient@home infra-structure, where it will ease the integration of applications to the platform, and facilitate semantic interoperability between the applications....

  1. Electric fingerprint of voltage sensor domains

    Science.gov (United States)

    Souza, Caio S.; Amaral, Cristiano; Treptow, Werner

    2014-01-01

    A dynamic transmembrane voltage field has been suggested as an intrinsic element in voltage sensor (VS) domains. Here, the dynamic field contribution to the VS energetics was analyzed via electrostatic calculations applied to a number of atomistic structures made available recently. We find that the field is largely static along with the molecular motions of the domain, and more importantly, it is minimally modified across VS variants. This finding implies that sensor domains transfer approximately the same amount of gating charges when moving the electrically charged S4 helix between fixed microscopic configurations. Remarkably, the result means that the observed operational diversity of the domain, including the extension, rate, and voltage dependence of the S4 motion, as dictated by the free energy landscape theory, must be rationalized in terms of dominant variations of its chemical free energy. PMID:25422443

  2. Oversampling analysis in fractional Fourier domain

    Institute of Scientific and Technical Information of China (English)

    ZHANG Feng; TAO Ran; WANG Yue

    2009-01-01

    Oversampling is widely used in practical applications of digital signal processing. As the fractional Fourier transform has been developed and applied in signal processing fields, it is necessary to consider the oversampling theorem in the fractional Fourier domain. In this paper, the oversampling theorem in the fractional Fourier domain is analyzed. The fractional Fourier spectral relation between the original oversampled sequence and its subsequences is derived first, and then the expression for exact reconstruction of the missing samples in terms of the subsequences is obtained. Moreover, by taking a chirp signal as an example, it is shown that, reconstruction of the missing samples in the oversampled signal Is suitable in the fractional Fourier domain for the signal whose time-frequency distribution has the minimum support in the fractional Fourier domain.

  3. The domain-wall/QFT correspondence

    CERN Document Server

    Boonstra, H J; Townsend, P K

    1999-01-01

    We extend the correspondence between adS-supergravities and superconformal field theories on the adS boundary to a correspondence between gauged supergravities (typically with non-compact gauge groups) and quantum field theories on domain walls.

  4. Domain wall manipulation with a magnetic tip.

    Science.gov (United States)

    Stapelfeldt, T; Wieser, R; Vedmedenko, E Y; Wiesendanger, R

    2011-07-01

    A theoretical concept of local manipulation of magnetic domain walls is introduced. In the proposed procedure, a domain wall is driven by a spin-polarized current induced by a magnetic tip, as used in a scanning tunneling microscope, placed above a magnetic nanostripe and then moved along its long axis with a current flowing through the vacuum barrier. The angular momentum from the spin-polarized current exerts a torque on the magnetic moments underneath the tip and leads to a displacement of the domain wall. Particularly, the manipulation of a ferromagnetic 180° transverse domain wall has been studied by means of Landau-Lifshitz-Gilbert dynamics and Monte Carlo simulations. Different relative orientations of the tip and the sample magnetization have been considered. PMID:21797636

  5. Between-Domain Relations of Students’ Academic Emotions and Their Judgments of School Domain Similarity

    Directory of Open Access Journals (Sweden)

    Thomas eGoetz

    2014-10-01

    Full Text Available With the aim to deepen our understanding of the between-domain relations of academic emotions, a series of three studies was conducted. We theorized that between-domain relations of trait (i.e., habitual emotions reflected students’ judgments of domain similarities, whereas between-domain relations of state (i.e., momentary emotions did not. This supposition was based on the accessibility model of emotional self-report, according to which individuals’ beliefs tend to strongly impact trait, but not state emotions. The aim of Study 1 (interviews; N = 40; 8th and 11th graders was to gather salient characteristics of academic domains from students’ perspective. In Study 2 (N=1709; 8th and 11th graders the 13 characteristics identified in Study 1 were assessed along with academic emotions in four different domains (mathematics, physics, German, and English using a questionnaire-based trait assessment. With respect to the same domains, state emotions were assessed in Study 3 (N = 121; 8th and 11th graders by employing an experience sampling approach. In line with our initial assumptions, between-domain relations of trait but not state academic emotions reflected between-domain relations of domain characteristics. Implications for research and practice are discussed.

  6. The Evolving Domain of Entrepreneurship Research

    OpenAIRE

    Carlsson, Bo; Braunerhjelm, Pontus; McKelvey, Maureen; Olofsson, Christer; Persson, Lars; Ylinenpää, Håkan

    2013-01-01

    Research on entrepreneurship has flourished in recent years and is evolving rapidly. This paper explores the history of entrepreneurship research, how the research domain has evolved, and its current status as an academic field. The need to concretize these issues stems partly from a general interest to define the current research domain, partly from the more specific tasks confronting the prize committee of the Global Award for Entrepreneurship Research. Entrepreneurship has developed in ma...

  7. Electromechanical Properties of Multi-Domain Ferroelectrics

    OpenAIRE

    Ahluwalia, Rajeev; Lookman, Turab; Saxena, Avadh; Cao, Wenwu

    2003-01-01

    We study theoretically the influence of the underlying domain microstructure on the electromechanical properties of ferroelectrics. Our calculations are based on a continuum approach that incorporates the long-range elastic and electrostatic interactions. The theory is used to simulate the piezoelectric properties of a two dimensional model ferroelectric crystal. Simulation results indicate that the electromechanical response of the ferroelectric is strongly dependent on the domain microsctru...

  8. Dual-domain point diffraction interferometer.

    Science.gov (United States)

    Naulleau, P P; Goldberg, K A

    1999-06-01

    The phase-shifting point diffraction interferometer has recently been developed and implemented at Lawrence Berkeley National Laboratory to meet the significant metrology challenge of characterizing extreme ultraviolet projection lithography systems. Here we present a refined version of this interferometer that overcomes the original design's susceptibility to noise attributed to scattered light. The theory of the new hybrid spatial- and temporal-domain (dual-domain) point diffraction interferometer is described in detail and experimental results are presented. PMID:18319953

  9. Cross-domain inhibition of TACE ectodomain

    DEFF Research Database (Denmark)

    Tape, Christopher J; Willems, Sofie H; Dombernowsky, Sarah L;

    2011-01-01

    target for the treatment of cancer and arthritis. Prior attempts to antagonize cell-surface TACE activity have focused on small-molecule inhibition of the metalloprotease active site. Given the highly conserved nature of metalloprotease active sites, this paradigm has failed to produce a truly specific...... individual antibody variable domains to desired epitopes. The resulting "cross-domain" human antibody is a previously undescribed selective TACE antagonist and provides a unique alternative to small-molecule metalloprotease inhibition....

  10. Flavor changing strings and domain walls

    International Nuclear Information System (INIS)

    We consider the cosmological consequences of a spontaneous breaking of non-abelian discrete symmetries, which may appear as a natural remnant of a continuous symmetry, such as a family symmetry. The result may be a stable domain wall across which an electron would turn into a muon (orνe into νμ) or a flavor analogue of an Alice string-domain wall structure with the same property. (author). 16 refs

  11. Domain-Specific Modelling Languages in Bigraphs

    OpenAIRE

    Perrone, Gian David

    2013-01-01

    Modelling is a ubiquitous activity in human endeavours, and the constructionof informatic models of many kinds is the key to understanding and managing the complexity of an increasingly computational world. We advocate the use of domain-specic modelling languages, instantiated within a \\tower" of models, in order to improve the utility of the models we build, and to ease the process of model construction by moving the languages we use to express such models closer to their respective domains....

  12. Loewner equations in multiply connected domains

    OpenAIRE

    Böhm, Christoph

    2016-01-01

    The first goal of this thesis is to generalize Loewner's famous differential equation to multiply connected domains. The resulting differential equations are known as Komatu--Loewner differential equations. We discuss Komatu--Loewner equations for canonical domains (circular slit disks, circular slit annuli and parallel slit half-planes). Additionally, we give a generalisation to several slits and discuss parametrisations that lead to constant coefficients. Moreover, we compare Komatu--Loewne...

  13. Gravitational Waves from Collapsing Vacuum Domains

    OpenAIRE

    Gleiser, Marcelo; Roberts, Ronald

    1998-01-01

    The breaking of an approximate discrete symmetry, the final stages of a first order phase transition, or a post-inflationary biased probability distribution for scalar fields are possible cosmological scenarios characterized by the presence of unstable domain wall networks. Combining analytical and numerical techniques, we show that the non-spherical collapse of these domains can be a powerful source of gravitational waves. We compute their contribution to the stochastic background of gravita...

  14. Quantum stochastic calculus with maximal operator domains

    OpenAIRE

    Lindsay, J Martin; Attal, Stéphane

    2004-01-01

    Quantum stochastic calculus is extended in a new formulation in which its stochastic integrals achieve their natural and maximal domains. Operator adaptedness, conditional expectations and stochastic integrals are all defined simply in terms of the orthogonal projections of the time filtration of Fock space, together with sections of the adapted gradient operator. Free from exponential vector domains, our stochastic integrals may be satisfactorily composed yielding quantum Itô formulas for op...

  15. Domain Specific Languages for Interactive Web Services

    DEFF Research Database (Denmark)

    Brabrand, Claus

    This dissertation shows how domain specific languages may be applied to the domain of interactive Web services to obtain flexible, safe, and efficient solutions. We show how each of four key aspects of interactive Web services involving sessions, dynamic creation of HTML/XML documents, form field...... supports virtually all aspects of the development of interactive Web services and provides flexible, safe, and efficient solutions....

  16. Structured hints : extracting and abstracting domain expertise.

    Energy Technology Data Exchange (ETDEWEB)

    Hereld, M.; Stevens, R.; Sterling, T.; Gao, G. R.; Mathematics and Computer Science; California Inst. of Tech.; Louisiana State Univ.; Univ. of Delaware

    2009-03-16

    We propose a new framework for providing information to help optimize domain-specific application codes. Its design addresses problems that derive from the widening gap between the domain problem statement by domain experts and the architectural details of new and future high-end computing systems. The design is particularly well suited to program execution models that incorporate dynamic adaptive methodologies for live tuning of program performance and resource utilization. This new framework, which we call 'structured hints', couples a vocabulary of annotations to a suite of performance metrics. The immediate target is development of a process by which a domain expert describes characteristics of objects and methods in the application code that would not be readily apparent to the compiler; the domain expert provides further information about what quantities might provide the best indications of desirable effect; and the interactive preprocessor identifies potential opportunities for the domain expert to evaluate. Our development of these ideas is progressing in stages from case study, through manual implementation, to automatic or semi-automatic implementation. In this paper we discuss results from our case study, an examination of a large simulation of a neural network modeled after the neocortex.

  17. Renormalization group domains of the scalar Hamiltonian

    CERN Document Server

    Bagnuls, C

    2000-01-01

    Using the local potential approximation of the exact renormalization group(RG) equation, we show the various domains of values of the parameters of theO(1)-symmetric scalar hamiltonian. In three dimensions, in addition to theusual critical surface $S_{\\text{c}}$ (attraction domain of the Wilson-Fisherfixed point), we explicitly show the existence of a first-order phasetransition domain $S_{\\text{f}}$ separated from $S_{\\text{c}}$ by thetricritical surface $S_{\\text{t}}$ (attraction domain of the Gaussian fixedpoint). $S_{\\text{f}}$ and $S_{\\text{c}}$ are two distinct domains of repulsionfor the Gaussian fixed point, but $S_{\\text{f}}$ is not the basin of attractionof a fixed point. $S_{\\text{f}}$ is characterized by an endless renormalizedtrajectory lying entirely in the domain of negative values of the $\\phi^{4}$-coupling. This renormalized trajectory exists also in four dimensionsmaking the Gaussian fixed point ultra-violet stable (and the $\\phi_{4}^{4}$renormalized field theory asymptotically free but with...

  18. Java Transactional Domain Programmers guide V 0.2

    OpenAIRE

    Machens, Holger

    2011-01-01

    Anleitung zur Installation und Nutzung des Eclipse Plug-ins "Java Transactional Domain". Programmers guide for the Java Transactional Domain plug-in for Eclipse. Anleitung zur Installation und Nutzung des Eclipse Plug-ins "Java Transactional Domain".

  19. Human-computer interface incorporating personal and application domains

    Science.gov (United States)

    Anderson, Thomas G.

    2004-04-20

    The present invention provides a human-computer interface. The interface includes provision of an application domain, for example corresponding to a three-dimensional application. The user is allowed to navigate and interact with the application domain. The interface also includes a personal domain, offering the user controls and interaction distinct from the application domain. The separation into two domains allows the most suitable interface methods in each: for example, three-dimensional navigation in the application domain, and two- or three-dimensional controls in the personal domain. Transitions between the application domain and the personal domain are under control of the user, and the transition method is substantially independent of the navigation in the application domain. For example, the user can fly through a three-dimensional application domain, and always move to the personal domain by moving a cursor near one extreme of the display.

  20. Human-computer interface incorporating personal and application domains

    Science.gov (United States)

    Anderson, Thomas G.

    2011-03-29

    The present invention provides a human-computer interface. The interface includes provision of an application domain, for example corresponding to a three-dimensional application. The user is allowed to navigate and interact with the application domain. The interface also includes a personal domain, offering the user controls and interaction distinct from the application domain. The separation into two domains allows the most suitable interface methods in each: for example, three-dimensional navigation in the application domain, and two- or three-dimensional controls in the personal domain. Transitions between the application domain and the personal domain are under control of the user, and the transition method is substantially independent of the navigation in the application domain. For example, the user can fly through a three-dimensional application domain, and always move to the personal domain by moving a cursor near one extreme of the display.

  1. Eukaryotic protein domains as functional units of cellular evolution

    DEFF Research Database (Denmark)

    Jin, Jing; Xie, Xueying; Chen, Chen;

    2009-01-01

    of different domain types to assess the molecular compartment occupied by each domain. This reveals that specific subsets of domains demarcate particular cellular processes, such as growth factor signaling, chromatin remodeling, apoptotic and inflammatory responses, or vesicular trafficking. We suggest...

  2. Domain adaptation of statistical machine translation with domain-focused web crawling

    OpenAIRE

    Pecina, Pavel; Toral, Antonio; Papavassiliou, Vassilis; Prokopidis, Prokopis; Tamchyna, Aleš; Way, Andy; VAN GENABITH, Josef

    2014-01-01

    In this paper, we tackle the problem of domain adaptation of statistical machine translation (SMT) by exploiting domain-specific data acquired by domain-focused crawling of text from the World Wide Web. We design and empirically evaluate a procedure for automatic acquisition of monolingual and parallel text and their exploitation for system training, tuning, and testing in a phrase-based SMT framework. We present a strategy for using such resources depending on their availability and quantity...

  3. Diligence of Domain Engineering in Accounting Management System

    OpenAIRE

    Mukesh Arya

    2012-01-01

    This paper presents on domain feature modeling, domain architecture design and domain implementation in an enterprise. This paper demonstrates the accounting management feature modeling based on the extended (Feature-Oriented Domain Analysis) FODA method and system architecture of accounting management domain, integrates Aspect Object Oriented Programming technology with domain implementation, and designs a whippersnapper AOP framework based on the object proxy pattern to separates crosscutti...

  4. A new and unexpected domain-domain interaction in the AraC protein.

    Science.gov (United States)

    Cole, Stephanie Dirla; Schleif, Robert

    2012-05-01

    An interaction between the dimerization domains and DNA binding domains of the dimeric AraC protein has previously been shown to facilitate repression of the Escherichia coli araBAD operon by AraC in the absence of arabinose. A new interaction between the domains of AraC in the presence of arabinose is reported here, the regulatory consequences of which are unknown. Evidence for the interaction is the following: the dissociation rate of arabinose-bound AraC from half-site DNA is considerably faster than that of free DNA binding domain, and the affinity of the dimerization domains for arabinose is increased when half-site DNA is bound. In addition, an increase in the fluorescence intensity of tryptophan residues located in the arabinose-bound dimerization domain is observed upon binding of half-site DNA to the DNA binding domains. Direct physical evidence of the new domain-domain interaction is demonstrated by chemical crosslinking and NMR experiments. PMID:22383259

  5. Low energy electron imaging of domains and domain walls in magnesium-doped lithium niobate

    Science.gov (United States)

    Nataf, G. F.; Grysan, P.; Guennou, M.; Kreisel, J.; Martinotti, D.; Rountree, C. L.; Mathieu, C.; Barrett, N.

    2016-01-01

    The understanding of domain structures, specifically domain walls, currently attracts a significant attention in the field of (multi)-ferroic materials. In this article, we analyze contrast formation in full field electron microscopy applied to domains and domain walls in the uniaxial ferroelectric lithium niobate, which presents a large 3.8 eV band gap and for which conductive domain walls have been reported. We show that the transition from Mirror Electron Microscopy (MEM – electrons reflected) to Low Energy Electron Microscopy (LEEM – electrons backscattered) gives rise to a robust contrast between domains with upwards (Pup) and downwards (Pdown) polarization, and provides a measure of the difference in surface potential between the domains. We demonstrate that out-of-focus conditions of imaging produce contrast inversion, due to image distortion induced by charged surfaces, and also carry information on the polarization direction in the domains. Finally, we show that the intensity profile at domain walls provides experimental evidence for a local stray, lateral electric field. PMID:27608605

  6. Methodology of time-domain and frequency-domain calibration and equivalence for EMP sensor

    International Nuclear Information System (INIS)

    In order to measure the waveform and amplitude of EMP accurately, the sensors need to be calibrated under the standard fields in the TEM or GTEM cell. A set of calibration system is discussed. A highly accurate method of calibrating such sensors is applicable to techniques in both the frequency domain and in the time domain. The complete frequency-domain transfer function or the time-domain impulse response function of sensor system can be obtained, thus allowing deconvolution processes to be used to remove perturbations from the measurement waveform by the instrumentation and TEM cell. (authors)

  7. Low energy electron imaging of domains and domain walls in magnesium-doped lithium niobate.

    Science.gov (United States)

    Nataf, G F; Grysan, P; Guennou, M; Kreisel, J; Martinotti, D; Rountree, C L; Mathieu, C; Barrett, N

    2016-01-01

    The understanding of domain structures, specifically domain walls, currently attracts a significant attention in the field of (multi)-ferroic materials. In this article, we analyze contrast formation in full field electron microscopy applied to domains and domain walls in the uniaxial ferroelectric lithium niobate, which presents a large 3.8 eV band gap and for which conductive domain walls have been reported. We show that the transition from Mirror Electron Microscopy (MEM - electrons reflected) to Low Energy Electron Microscopy (LEEM - electrons backscattered) gives rise to a robust contrast between domains with upwards (Pup) and downwards (Pdown) polarization, and provides a measure of the difference in surface potential between the domains. We demonstrate that out-of-focus conditions of imaging produce contrast inversion, due to image distortion induced by charged surfaces, and also carry information on the polarization direction in the domains. Finally, we show that the intensity profile at domain walls provides experimental evidence for a local stray, lateral electric field. PMID:27608605

  8. A Review of Domain Modelling and Domain Imaging Techniques in Ferroelectric Crystals

    Directory of Open Access Journals (Sweden)

    John E. Huber

    2011-02-01

    Full Text Available The present paper reviews models of domain structure in ferroelectric crystals, thin films and bulk materials. Common crystal structures in ferroelectric materials are described and the theory of compatible domain patterns is introduced. Applications to multi-rank laminates are presented. Alternative models employing phase-field and related techniques are reviewed. The paper then presents methods of observing ferroelectric domain structure, including optical, polarized light, scanning electron microscopy, X-ray and neutron diffraction, atomic force microscopy and piezo-force microscopy. Use of more than one technique for unambiguous identification of the domain structure is also described.

  9. Composite Eshelby model and domain band geometries of ferroelectric ceramics

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A method of composite Eshelby inclusion is proposed for aferroelectric grain with domain switching embedded in a polycrystalline ferroelectric matrix. The method quantifies the twinning structure due to spontaneous polarization, as well as the conventional and non-conventional domain structures after poling induced domain reorientation of 90 degree. The predicted parameters include the volume fraction, the thickness, and the surface inclination angle of switched domain plates. The domain wall energy for non-conventional domain structures is derived in terms of the arrays of misfit dislocations. The domain geometries predicted by the present work agree with the measured domain morphology near an indentation crack tip when subjected to lateral electric field.

  10. Wavefield Extrapolation in Pseudo-depth Domain

    KAUST Repository

    Ma, Xuxin

    2011-12-11

    Wave-equation based seismic migration and inversion tools are widely used by the energy industry to explore hydrocarbon and mineral resources. By design, most of these techniques simulate wave propagation in a space domain with the vertical axis being depth measured from the surface. Vertical depth is popular because it is a straightforward mapping of the subsurface space. It is, however, not computationally cost-effective because the wavelength changes with local elastic wave velocity, which in general increases with depth in the Earth. As a result, the sampling per wavelength also increases with depth. To avoid spatial aliasing in deep fast media, the seismic wave is oversampled in shallow slow media and therefore increase the total computation cost. This issue is effectively tackled by using the vertical time axis instead of vertical depth. This is because in a vertical time representation, the "wavelength" is essentially time period for vertical rays. This thesis extends the vertical time axis to the pseudo-depth axis, which features distance unit while preserving the properties of the vertical time representation. To explore the potentials of doing wave-equation based imaging in the pseudo-depth domain, a Partial Differential Equation (PDE) is derived to describe acoustic wave in this new domain. This new PDE is inherently anisotropic because the use of a constant vertical velocity to convert between depth and vertical time. Such anisotropy results in lower reflection coefficients compared with conventional space domain modeling results. This feature is helpful to suppress the low wavenumber artifacts in reverse-time migration images, which are caused by the widely used cross-correlation imaging condition. This thesis illustrates modeling acoustic waves in both conventional space domain and pseudo-depth domain. The numerical tool used to model acoustic waves is built based on the lowrank approximation of Fourier integral operators. To investigate the potential

  11. Generalized vector calculus on convex domain

    Science.gov (United States)

    Agrawal, Om P.; Xu, Yufeng

    2015-06-01

    In this paper, we apply recently proposed generalized integral and differential operators to develop generalized vector calculus and generalized variational calculus for problems defined over a convex domain. In particular, we present some generalization of Green's and Gauss divergence theorems involving some new operators, and apply these theorems to generalized variational calculus. For fractional power kernels, the formulation leads to fractional vector calculus and fractional variational calculus for problems defined over a convex domain. In special cases, when certain parameters take integer values, we obtain formulations for integer order problems. Two examples are presented to demonstrate applications of the generalized variational calculus which utilize the generalized vector calculus developed in the paper. The first example leads to a generalized partial differential equation and the second example leads to a generalized eigenvalue problem, both in two dimensional convex domains. We solve the generalized partial differential equation by using polynomial approximation. A special case of the second example is a generalized isoperimetric problem. We find an approximate solution to this problem. Many physical problems containing integer order integrals and derivatives are defined over arbitrary domains. We speculate that future problems containing fractional and generalized integrals and derivatives in fractional mechanics will be defined over arbitrary domains, and therefore, a general variational calculus incorporating a general vector calculus will be needed for these problems. This research is our first attempt in that direction.

  12. Dipole interactions in doubly-periodic domains

    CERN Document Server

    Tsang, Alan Cheng Hou

    2013-01-01

    We consider the interactions of finite dipoles in a doubly-periodic domain. A finite dipole is a pair of equal and opposite strength point vortices separated by a finite distance. The dynamics of multiple finite dipoles in an unbounded inviscid uid was first proposed by Tchieu, Kanso & Newton in [1] as a model that captures the "far- field" hydrodynamic interactions in fish schools. In this paper, we formulate the equations of motion governing the dynamics of finite-dipoles in a doubly-periodic domain. We show that a single dipole in a doubly-periodic domain exhibits periodic and aperiodic behavior, in contrast to a single dipole in an unbounded domain. In the case of two dipoles in doubly-periodic domain, we identify a number of interesting trajectories including collision, collision avoidance, and passive synchronization of the dipoles. We then examine two types of dipole lattices: rectangular and diamond. We verify that these lattices are in a state of relative equilibrium and show that the rectangular...

  13. Domain-specific temporal discounting and temptation

    Directory of Open Access Journals (Sweden)

    Eli Tsukayama

    2010-04-01

    Full Text Available In this investigation, we test whether temporal discounting is domain-specific (i.e., compared to other people, can an individual have a relatively high discount rate for one type of reward but a relatively low discount rate for another?, and we examine whether individual differences in the types of rewards one finds tempting explain domain-specificity in discount rates. Adults discounted delayed rewards they found particularly tempting (defined as the visceral attraction to and enjoyment of a reward more steeply than did adults who did not find the rewards as tempting, contrary to what might be expected from the magnitude effect. Furthermore, we found significant group by domain interactions (e.g., chip lovers who do not like beer have relatively high discount rates for chips and relatively low discount rates for beer, whereas beer lovers who do not like chips showed the opposite pattern. These results suggest that domain-specificity in temptation partially accounts for corresponding domain-specificity in temporal discounting.

  14. Gravitational waves from Higgs domain walls

    Energy Technology Data Exchange (ETDEWEB)

    Kitajima, Naoya, E-mail: kitajima@tuhep.phys.tohoku.ac.jp [Department of Physics, Tohoku University, Sendai 980-8578 (Japan); Takahashi, Fuminobu, E-mail: fumi@tuhep.phys.tohoku.ac.jp [Department of Physics, Tohoku University, Sendai 980-8578 (Japan); Kavli IPMU, TODIAS, University of Tokyo, Kashiwa 277-8583 (Japan)

    2015-05-18

    The effective potential for the Standard Model Higgs field allows two quasi-degenerate vacua; one is our vacuum at the electroweak scale, while the other is at a much higher scale. The latter minimum may be at a scale much smaller than the Planck scale, if the potential is lifted by new physics. This gives rise to a possibility of domain wall formation after inflation. If the high-scale minimum is a local minimum, domain walls are unstable and disappear through violent annihilation processes, producing a significant amount of gravitational waves. We estimate the amount of gravitational waves produced from unstable domain walls in the Higgs potential and discuss detectability with future experiments.

  15. Condon domain phase diagram for silver

    International Nuclear Information System (INIS)

    We present the Condon domain phase diagram for a silver single crystal measured in magnetic fields up to 28 T and temperatures down to 1.3 K. A standard ac method with a pickup coil system is used at low frequency for the measurements of the de Haas-van Alphen effect (dHvA). The transition point from the state of homogeneous magnetization to the inhomogeneous Condon domain state (CDS) is found as the point where a small irreversibility in the dHvA magnetization arises, as manifested by an extremely nonlinear response in the pickup voltage showing threshold character. The third harmonic content in the ac response is used to determine with high precision the CDS phase boundary. The experimentally determined Condon domain phase diagram is in good agreement with the theoretical prediction calculated by the standard Lifshitz-Kosevich formula.

  16. Multilevel domain decomposition for electronic structure calculations

    International Nuclear Information System (INIS)

    We introduce a new multilevel domain decomposition method (MDD) for electronic structure calculations within semi-empirical and density functional theory (DFT) frameworks. This method iterates between local fine solvers and global coarse solvers, in the spirit of domain decomposition methods. Using this approach, calculations have been successfully performed on several linear polymer chains containing up to 40,000 atoms and 200,000 atomic orbitals. Both the computational cost and the memory requirement scale linearly with the number of atoms. Additional speed-up can easily be obtained by parallelization. We show that this domain decomposition method outperforms the density matrix minimization (DMM) method for poor initial guesses. Our method provides an efficient preconditioner for DMM and other linear scaling methods, variational in nature, such as the orbital minimization (OM) procedure

  17. Domain Theory, Its Models and Concepts

    DEFF Research Database (Denmark)

    Andreasen, Mogens Myrup; Howard, Thomas J.; Bruun, Hans Peter Lomholt

    2014-01-01

    Domain Theory is a systems approach for the analysis and synthesis of products. Its basic idea is to view a product as systems of activities, organs and parts and to define structure, elements, behaviour and function in these domains. The theory is a basis for a long line of research contributions...... and industrial applications especially for the DFX areas (not reported here) and for product modelling. The theory therefore contains a rich ontology of interrelated concepts. The Domain Theory is not aiming to create normative methods but the creation of a collection of concepts related to design phenomena......, which can support design work and to form elements of designers’ mindsets and thereby their practice. The theory is a model-based theory, which means it is composed of concepts and models, which explains certain design phenomena. Many similar theories are described in the literature with differences...

  18. Cross domains Arabic named entity recognition system

    KAUST Repository

    Al-Ahmari, S. Saad

    2016-07-11

    Named Entity Recognition (NER) plays an important role in many Natural Language Processing (NLP) applications such as; Information Extraction (IE), Question Answering (QA), Text Clustering, Text Summarization and Word Sense Disambiguation. This paper presents the development and implementation of domain independent system to recognize three types of Arabic named entities. The system works based on a set of domain independent grammar-rules along with Arabic part of speech tagger in addition to gazetteers and lists of trigger words. The experimental results shown, that the system performed as good as other systems with better results in some cases of cross-domains corpora. © (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.

  19. On thick domain walls in general relativity

    Science.gov (United States)

    Goetz, Guenter; Noetzold, Dirk

    1989-01-01

    Planar scalar field configurations in general relativity differ considerably from those in flat space. It is shown that static domain walls of finite thickness in curved space-time do not possess a reflection symmetry. At infinity, the space-time tends to the Taub vacuum on one side of the wall and to the Minkowski vacuum (Rindler space-time) on the other. Massive test particles are always accelerated towards the Minkowski side, i.e., domain walls are attractive on the Taub side, but repulsive on the Minkowski side (Taub-vacuum cleaner). It is also proved that the pressure in all directions is always negative. Finally, a brief comment is made concerning the possibility of infinite, i.e., bigger than horizon size, domain walls in our universe. All of the results are independent of the form of the potential V(phi) greater than or equal to 0 of the scalar field phi.

  20. Domain Size Distribution in Segregating Binary Superfluids

    Science.gov (United States)

    Takeuchi, Hiromitsu

    2016-05-01

    Domain size distribution in phase separating binary Bose-Einstein condensates is studied theoretically by numerically solving the Gross-Pitaevskii equations at zero temperature. We show that the size distribution in the domain patterns arising from the dynamic instability obeys a power law in a scaling regime according to the dynamic scaling analysis based on the percolation theory. The scaling behavior is kept during the relaxation dynamics until the characteristic domain size becomes comparable to the linear size of the system, consistent with the dynamic scaling hypothesis of the phase-ordering kinetics. Our numerical experiments indicate the existence of a different scaling regime in the size distribution function, which can be caused by the so-called coreless vortices.

  1. Collaborative Detection of Fast Flux Phishing Domains

    Directory of Open Access Journals (Sweden)

    Chenfeng Vincent Zhou

    2009-02-01

    Full Text Available Phishing is a significant security threat to users of Internet services. Nowadays, phishing has become more resilient to detection and trace-back with the invention of Fast Flux (FF service networks. We propose two approaches to correlate evidence from multiple DNS servers and multiple suspect FF domains. Real-world experiments show that our correlation approaches speed-up FF domain detection, based on an analytical model that we propose to quantify the number of DNS queries needed to confirm a FF domain. We also show how our correlation scheme can be implemented on a large scale by using a decentralized publish-subscribe correlation model called LarSID, which is more scalable than a fully centralized architecture.

  2. A Domain Description Language for Data Processing

    Science.gov (United States)

    Golden, Keith

    2003-01-01

    We discuss an application of planning to data processing, a planning problem which poses unique challenges for domain description languages. We discuss these challenges and why the current PDDL standard does not meet them. We discuss DPADL (Data Processing Action Description Language), a language for describing planning domains that involve data processing. DPADL is a declarative, object-oriented language that supports constraints and embedded Java code, object creation and copying, explicit inputs and outputs for actions, and metadata descriptions of existing and desired data. DPADL is supported by the IMAGEbot system, which we are using to provide automation for an ecological forecasting application. We compare DPADL to PDDL and discuss changes that could be made to PDDL to make it more suitable for representing planning domains that involve data processing actions.

  3. Quasiconformal Mappings and Weakly John Domains

    Institute of Scientific and Technical Information of China (English)

    褚玉明

    2003-01-01

    @@ Let D be a bounded domain in R2 and c (≥ 1) be a constant. We say that D is a c-Johndomain if there exists x0 ∈ D such that for any x ∈ D, there must be a rectifiable curve γ C D,which joins x and x0, satisfying l(γ(x, y)) ≤ cd(y, D) for any y ∈γ, where l(γ(x, y)) denotesthe Euclidean length of the subcurve γ between x and y, d(y, D) is the Euclidean distance fromy to the boundary D of D. We say that D is a John domain if D is a c-John domain for somec (≥ 1).

  4. Planning in Markov Stochastic Task Domains

    Directory of Open Access Journals (Sweden)

    Yong Lin

    2010-10-01

    Full Text Available In decision theoretic planning, a challenge for Markov decision processes (MDPs and partially observable Markov decision processes (POMDPs is, many problem domains contain big state spaces and complex tasks, which will result in poor solution performance. We develop a task analysis and modeling (TAM approach, in which the (POMDP model is separated into a task view and an action view. In the task view, TAM models the problem domain using a task equivalence model, with task-dependent abstract states and observations. We provide a learning algorithm to obtain the parameter values of task equivalence models. We present three typical examples to explain the TAM approach. Experimental results indicate our approach can greatly improve the computational capacity of task planning in Markov stochastic domains.

  5. Domain-Specific Modelling Languages in Bigraphs

    DEFF Research Database (Denmark)

    Perrone, Gian David

    Modelling is a ubiquitous activity in human endeavours, and the construction of informatic models of many kinds is the key to understanding and managing the complexity of an increasingly computational world. We advocate the use of domain-specic modelling languages, instantiated within a \\tower......" of models, in order to improve the utility of the models we build, and to ease the process of model construction by moving the languages we use to express such models closer to their respective domains. This thesis is concerned with the study of bigraphical reactive systems as a host for domain......-specic modelling languages. We present a number of novel technical developments, including a new complete meta-calculus presentation of bigraphical reactive systems, an abstract machine that instantiates to an abstract machine for any instance calculus, and a mechanism for dening declarative sorting predicates...

  6. Intellectual Growth in Children as a Function of Domain Specific and Domain General Working Memory Subgroups

    Science.gov (United States)

    Swanson, H. Lee

    2011-01-01

    This study examined whether children's growth on measures of fluid (Raven Colored Progressive Matrices) and crystallized (reading and math achievement) intelligence was attributable to domain-specific or domain-general functions of working memory (WM). A sample of 290 elementary school children was tested on measures of intelligence across three…

  7. SH3 Domains Differentially Stimulate Distinct Dynamin I Assembly Modes and G Domain Activity.

    Directory of Open Access Journals (Sweden)

    Sai Krishnan

    Full Text Available Dynamin I is a highly regulated GTPase enzyme enriched in nerve terminals which mediates vesicle fission during synaptic vesicle endocytosis. One regulatory mechanism involves its interactions with proteins containing Src homology 3 (SH3 domains. At least 30 SH3 domain-containing proteins bind dynamin at its proline-rich domain (PRD. Those that stimulate dynamin activity act by promoting its oligomerisation. We undertook a systematic parallel screening of 13 glutathione-S-transferase (GST-tagged endocytosis-related SH3 domains on dynamin binding, GTPase activity and oligomerisation. No correlation was found between dynamin binding and their potency to stimulate GTPase activity. There was limited correlation between the extent of their ability to stimulate dynamin activity and the level of oligomerisation, indicating an as yet uncharacterised allosteric coupling of the PRD and G domain. We examined the two variants, dynamin Iab and Ibb, which differ in the alternately splice middle domain α2 helix. They responded differently to the panel of SH3s, with the extent of stimulation between the splice variants varying greatly between the SH3s. This study reveals that SH3 binding can act as a heterotropic allosteric regulator of the G domain via the middle domain α2 helix, suggesting an involvement of this helix in communicating the PRD-mediated allostery. This indicates that SH3 binding both stabilises multiple conformations of the tetrameric building block of dynamin, and promotes assembly of dynamin-SH3 complexes with distinct rates of GTP hydrolysis.

  8. Electric-field-driven dynamics of magnetic domain walls in magnetic nanowires patterned on ferroelectric domains

    Science.gov (United States)

    Van de Wiele, Ben; Leliaert, Jonathan; Franke, Kévin J. A.; van Dijken, Sebastiaan

    2016-03-01

    Strong coupling of magnetic domain walls onto straight ferroelastic boundaries of a ferroelectric layer enables full and reversible electric-field control of magnetic domain wall motion. In this paper, the dynamics of this new driving mechanism is analyzed using micromagnetic simulations. We show that transverse domain walls with a near-180° spin structure are stabilized in magnetic nanowires and that electric fields can move these walls with high velocities. Above a critical velocity, which depends on material parameters, nanowire geometry and the direction of domain wall motion, the magnetic domain walls depin abruptly from the ferroelastic boundaries. Depinning evolves either smoothly or via the emission and annihilation of a vortex or antivortex core (Walker breakdown). In both cases, the magnetic domain wall slows down after depinning in an oscillatory fashion and eventually comes to a halt. The simulations provide design rules for hybrid ferromagnetic-ferroelectric domain-wall-based devices and indicate that material disorder and structural imperfections only influence Walker-breakdown-like depinning at high domain wall velocities.

  9. Domain and domain walls NMR spectra in R Co2 intermetallic compounds

    International Nuclear Information System (INIS)

    NMR signals in ferromagnets originate from domains and domain walls. THe technique has the ability to distinguish signals originating from these two regions, through the selection of the radiofrequency (RF) power level applied to the sample. The dependence of the spin echo amplitude upon the RF field intensity can give information on magnetic properties such as domain walls mobility, distribution of local magnetic anisotropies, etc. NMR spectra obtained under different RF intensities allow the investigation of different regions of the samples. In this paper we have applied this technique to the study of the spin-echo amplitude and of the spectra of 59 Co in the series of the Laves phase intermetallic compounds R Co2, where R=Gd, Dy, Tb at 4.2 K, as a function of the RF Field. The results were analyzed according to a model which takes into account several features characteristic of ferromagnetic powdered samples. These include the distribution of the direction of the hyperfine fielding respect to the RF field, the variation of the enhancement factor within the domain-walls, the distribution of wall areas, etc. The analysis suggests that whereas in Tb Co2 the NMR signals come purely from domain walls, in Dy Co2 they come mainly from domains. Gd Co2 behaves as an intermediate case where there exists a mixture of contributions to the NMR signals. In this case we were able to observe and measure separately the NMR spectra of nuclei from domains and domain walls. (author)

  10. Changing domains in human capital measurement

    Directory of Open Access Journals (Sweden)

    Pharny D. Chrysler-Fox

    2014-02-01

    Full Text Available Orientation: The management context is dynamic; this is especially evident in human capital as the primary source of value creation as opposed to physical and natural resources. In response, measurement methodologies have moved from a transactional approach (strategy implementation to a transformational approach (human capital contribution paradigm, as well as diverging into different purposes. To date, there has been little overlap on recent domains to consider in managing and measuring the contribution of the human resource function and employees, and how to unlock and add value.Research purpose: The aim of the study was to explore and describe changing domains within human capital management to be managed and measured.Motivation for the study: The motivation was to advance the understanding of changing measurement domains to aid practitioners to manage and measure the contribution of the human resource function and employees, in order to unlock and add value and ultimately contribute to the success of an organisation.Research design, approach and method: Unstructured, in-depth interview data of purposively selected cases from a selected panel of human resource practitioners specialising in human capital measurement was thematically analysed in this exploratory-descriptive investigation.Main findings: Findings suggested that seven domains should be managed and measured. These domains highlight new areas of impact and levels of management. In addition, crossdomain relationships in measurement allow for an understanding of the impact and potential value on which to capitalise.Practical/managerial implications: New domains to manage and measure focus the attention of practitioners beyond the transactional performance management paradigm to a transformational approach to influence the business strategy. Higher education institutions need to develop students’ cognitive skills to facilitate systems thinking.Contribution: This study suggests a new

  11. Clojure for domain-specific languages

    CERN Document Server

    Kelker, Ryan D

    2013-01-01

    An example-oriented approach to develop custom domain-specific languages.If you've already developed a few Clojure applications and wish to expand your knowledge on Clojure or domain-specific languages in general, then this book is for you. If you're an absolute Clojure beginner, then you may only find the detailed examples of the core Clojure components of value. If you've developed DSLs in other languages, this Lisp and Java-based book might surprise you with the power of Clojure.

  12. Research Perspectives on the Public Domain

    OpenAIRE

    Erickson, Kristofer; Kretschmer, Martin

    2014-01-01

    This document presents an edited transcript of the one-day event, ‘Research Perspectives on the Public Domain’, held at the University of Glasgow on 11thOctober, 2013. The public domain is a subject of vital interest to legal scholars, but its implications are far reaching – indeed, the public domain concept is germane to subjects as diverse as film and media studies, economics, political science and organisational theory. It was a central purpose of the workshop to arrive a...

  13. Detector nonlinearity in frequency-domain fluorometry.

    Science.gov (United States)

    Wirth, M J; Burbage, J D; Zulli, S L

    1993-02-20

    Frequency-domain fluorometry relies on the measurement of the phase and amplitudes of the Fourier components of the time-dependent fluorescence signal. Experimental results that show that a conventional photomultiplier is subject to intensity-dependent phase shifts are presented. The measurements indicate that this is a problem well below the maximum linear current of the photomultiplier response. These results have important implications in frequency-domain fluorescence anisotropy experiments, in which the parallel and the perpendicular components of the emission intensity are inherently different from one another: a phase shift can be introduced by the photomultiplier. PMID:20802776

  14. Inviscid incompressible limits on expanding domains

    OpenAIRE

    Feireisl, E.; Nečasová, Š. (Šárka); Y. Sun

    2014-01-01

    We consider the inviscid incompressible limit of the compressible Navier-Stokes system on a large domain, the radius of which becomes infinite in the asymptotic limit. We show that the limit solutions satisfy the incompressible Euler system on the whole physical space R3 as long as the radius of the domain is larger than the speed of acoustic waves inversely proportional to the Mach number. The rate of convergence is estimated in terms of the Mach and Reynolds numbers and the radius of the fa...

  15. Gravitational Waves from Collapsing Vacuum Domains

    CERN Document Server

    Gleiser, Marcello; Gleiser, Marcelo; Roberts, Ronald

    1998-01-01

    The breaking of an approximate discrete symmetry, the final stages of a first order phase transition, or a post-inflationary biased probability distribution for scalar fields are possible cosmological scenarios characterized by the presence of unstable domain wall networks. Combining analytical and numerical techniques, we show that the non-spherical collapse of these domains can be a powerful source of gravitational waves. We compute their contribution to the stochastic background of gravitational radiation and explore their observability by present and future gravitational wave detectors.

  16. Magnetic domains the analysis of magnetic microstructures

    CERN Document Server

    Hubert, Alex

    1998-01-01

    The book gives a systematic and comprehensive survey of the complete area of magnetic microstructures. It reaches from micromagnetism of nanoparticles to complex structures of extended magnetic materials. The book starts with a comprehensive evaluation of traditional and modern experimental methods for the observation of magnetic domains and continues with the treatment of important methods for the theoretical analysis of magnetic microcstructures. A survey of the necessary techniques in materials characterization is given. The book offers an observation and analysis of magnetic domains in all

  17. Load Estimation by Frequency Domain Decomposition

    DEFF Research Database (Denmark)

    Pedersen, Ivar Chr. Bjerg; Hansen, Søren Mosegaard; Brincker, Rune;

    2007-01-01

    When performing operational modal analysis the dynamic loading is unknown, however, once the modal properties of the structure have been estimated, the transfer matrix can be obtained, and the loading can be estimated by inverse filtering. In this paper loads in frequency domain are estimated by...... analysis of simulated responses of a 4 DOF system, for which the exact modal parameters are known. This estimation approach entails modal identification of the natural eigenfrequencies, mode shapes and damping ratios by the frequency domain decomposition technique. Scaled mode shapes are determined by use...

  18. [Development of domain specific search engines].

    Science.gov (United States)

    Takai, T; Tokunaga, M; Maeda, K; Kaminuma, T

    2000-01-01

    As cyber space exploding in a pace that nobody has ever imagined, it becomes very important to search cyber space efficiently and effectively. One solution to this problem is search engines. Already a lot of commercial search engines have been put on the market. However these search engines respond with such cumbersome results that domain specific experts can not tolerate. Using a dedicate hardware and a commercial software called OpenText, we have tried to develop several domain specific search engines. These engines are for our institute's Web contents, drugs, chemical safety, endocrine disruptors, and emergent response for chemical hazard. These engines have been on our Web site for testing. PMID:11534132

  19. Fake Supergravity and Domain Wall Stability

    CERN Document Server

    Freedman, D Z; Schnabl, M; Skenderis, K

    2003-01-01

    We review the generalized Witten-Nester spinor stability argument for flat domain wall solutions of gravitational theories. Neither the field theory nor the solution need be supersymmetric. Nor is the space-time dimension restricted. We develop the non-trivial extension required for AdS-sliced domain walls and apply this to show that the recently proposed "Janus" solution of Type IIB supergravity is stable non-perturbatively for a broad class of deformations. Generalizations of this solution to arbitrary dimension and a simple curious linear dilaton solution of Type IIB supergravity are byproducts of this work.

  20. Totally geodesic discs in strongly convex domains

    OpenAIRE

    Gaussier, Herve; Seshadri, Harish

    2012-01-01

    We prove that Kobayashi isometries between strongly convex domains are holomorphic or anti-holomorphic. More precisely, let $n_1, n_2$ be positive integers and let $\\Omega_i \\subset \\C^{n_i}, \\ i=1,2$, be bounded $C^3$ strongly convex domains. If $\\phi: (\\Omega_1, d^K_{\\Omega_1}) \\rightarrow (\\Omega_2, d^K_{\\Omega_2})$ is an isometry, i.e. $ d^K_\\Omega_{n_2}(f(\\zeta),f(\\eta)) = d^K_{n_1} (\\zeta,\\eta)$ for all $\\zeta,\\eta \\in \\Omega_1,$ then $\\phi$ is either holomorphic or anti-holomorphic.

  1. Irregular Homogeneity Domains in Ternary Intermetallic Systems

    OpenAIRE

    Jean-Marc Joubert; Mohamed Andasmas; Jean-Claude Crivello

    2015-01-01

    Ternary intermetallic A–B–C systems sometimes have unexpected behaviors. The present paper examines situations in which there is a tendency to simultaneously form the compounds ABx, ACx and BCx with the same crystal structure. This causes irregular shapes of the phase homogeneity domains and, from a structural point of view, a complete reversal of site occupancies for the B atom when crossing the homogeneity domain. This work reviews previous studies done in the systems Fe–Nb–Zr, Hf–Mo–Re, Hf...

  2. Cosmological evolution of domain wall networks

    International Nuclear Information System (INIS)

    We have studied the cosmological evolution of domain wall networks in two, three, and four spatial dimensions using high-resolution field theory simulations. The dynamical range and number of our simulations is larger than in previous works, but does not allow us to exclude previous hints of deviations to the naively expected scale-invariant evolution. These results therefore suggest that the approach of domain wall networks to linear scaling is a much slower process than that of cosmic strings, which has been previously characterized in detail

  3. Skyrmions from Instantons inside Domain Walls

    CERN Document Server

    Eto, M; Ohashi, K; Tong, D; Eto, Minoru; Nitta, Muneto; Ohashi, Keisuke; Tong, David

    2005-01-01

    Some years ago, Atiyah and Manton described a method to construct approximate Skyrmion solutions from Yang-Mills instantons. Here we present a dynamical realization of this construction using domain walls in a five-dimensional gauge theory. The non-abelian gauge symmetry is broken in each vacuum but restored in the core of the domain wall, allowing instantons to nestle inside the wall. We show that the worldvolume dynamics of the wall is given by the Skyrme model, including the four-derivative term, and the instantons appear as Skyrmions.

  4. Predicting detection performance with model observers: Fourier domain or spatial domain?

    Science.gov (United States)

    Chen, Baiyu; Yu, Lifeng; Leng, Shuai; Kofler, James; Favazza, Christopher; Vrieze, Thomas; McCollough, Cynthia

    2016-03-01

    The use of Fourier domain model observer is challenged by iterative reconstruction (IR), because IR algorithms are nonlinear and IR images have noise texture different from that of FBP. A modified Fourier domain model observer, which incorporates nonlinear noise and resolution properties, has been proposed for IR and needs to be validated with human detection performance. On the other hand, the spatial domain model observer is theoretically applicable to IR, but more computationally intensive than the Fourier domain method. The purpose of this study is to compare the modified Fourier domain model observer to the spatial domain model observer with both FBP and IR images, using human detection performance as the gold standard. A phantom with inserts of various low contrast levels and sizes was repeatedly scanned 100 times on a third-generation, dual-source CT scanner at 5 dose levels and reconstructed using FBP and IR algorithms. The human detection performance of the inserts was measured via a 2-alternative-forced-choice (2AFC) test. In addition, two model observer performances were calculated, including a Fourier domain non-prewhitening model observer and a spatial domain channelized Hotelling observer. The performance of these two mode observers was compared in terms of how well they correlated with human observer performance. Our results demonstrated that the spatial domain model observer correlated well with human observers across various dose levels, object contrast levels, and object sizes. The Fourier domain observer correlated well with human observers using FBP images, but overestimated the detection performance using IR images.

  5. Survivability-enhancing routing scheme for multi-domain networks

    DEFF Research Database (Denmark)

    Li, Xiaohua; Ruepp, Sarah Renée; Manolova, Anna Vasileva;

    2008-01-01

    domain level disjoint paths. Our work is based on the aggregated representation of transit domains. The aggregated scheme we use is obtaining the shortest path between each pair of border routers for the associated domain. We also propose to use a single node to represent the destination domain, thereby...

  6. Reporting Valid and Reliable Overall Scores and Domain Scores

    Science.gov (United States)

    Yao, Lihua

    2010-01-01

    In educational assessment, overall scores obtained by simply averaging a number of domain scores are sometimes reported. However, simply averaging the domain scores ignores the fact that different domains have different score points, that scores from those domains are related, and that at different score points the relationship between overall…

  7. Automorphism group of exceptional symmetric domains R_v

    Institute of Scientific and Technical Information of China (English)

    许以超

    2000-01-01

    The exceptional symmetric Siegel domain Rv(16) in 16 is defined. The exceptional clas-sical domain .Rv(16) = T( Rv(16)) is computed, where r is the Bergman mapping of the Siegel domain Rv(16). And holomorphical automorphism group Aut ( Rv(16)) of the exceptional symmetric Siegel domain Rv(16) is presented.

  8. A NONOVERLAPPING DOMAIN DECOMPOSITION METHOD FOR EXTERIOR 3-D PROBLEM

    Institute of Scientific and Technical Information of China (English)

    De-hao Yu; Ji-ming Wu; Ji-ming Wu

    2001-01-01

    In this paper, a nonoverlapping domain decomposition method, which is based on the natural boundary reduction(cf. [4, 13, 15]), is developed to solve the boundary value problem in exterior three-dimensional domain of general shape. Convergence analyses both for the exterior spherical domain and the general exterior domain are made. Some numerical examples are also provided to illustrate the method.

  9. The Loyal Opposition Comments on Plan Domain Description Languages

    Science.gov (United States)

    Frank, Jeremy; Golden, Keith; Jonsson, Ari

    2003-01-01

    In this paper we take a critical look at PDDL 2.1 as designers and users of plan domain description languages. We describe planning domains that have features which are hard to model using PDDL 2.1. We then offer some suggestions on domain description language design, and describe how these suggestions make modeling our chosen domains easier.

  10. Domain Endurants: An Analysis and Description Process Model

    DEFF Research Database (Denmark)

    Bjørner, Dines

    2014-01-01

    We present a summary, Sect. 2, of a structure of domain analysis and description concepts: techniques and tools. And we link, in Sect. 3, these concepts, embodied in domain analysis prompts and domain description prompts, in a model of how a diligent domain analyser cum describer would use them. We...

  11. A Prop erty of Convex Mappings on the Classical Domains

    Institute of Scientific and Technical Information of China (English)

    FENG Shu-xia; LI Hong-jun

    2014-01-01

    In this paper, we give a property of normalized biholomorphic convex mappings on the first, second and third classical domains: for any Z0 belongs to the classical domains, f maps each neighbourhood with the center Z0, which is contained in the classical domains, to a convex domain.

  12. Sobolev spaces on bounded symmetric domains

    Czech Academy of Sciences Publication Activity Database

    Engliš, Miroslav

    2015-01-01

    Roč. 60, č. 12 (2015), s. 1712-1726. ISSN 1747-6933 Institutional support: RVO:67985840 Keywords : bounded symmetric domain * Sobolev space * Bergman space Subject RIV: BA - General Mathematics Impact factor: 0.610, year: 2014 http://www.tandfonline.com/doi/abs/10.1080/17476933.2015.1043910

  13. Vector solitons with an embedded domain wall

    NARCIS (Netherlands)

    Kevrekidis, P.G.; Susanto, H.; Carretero-Gonzalez, R.; Malomed, B.A.; Frantzeskakis, D.J.

    2005-01-01

    We present a class of soliton solutions to a system of two coupled nonlinear Schrödinger equations, with an intrinsic domain wall (DW) which separates regions occupied by two different fields. The model describes a binary mixture of two Bose-Einstein condensates (BECs) with interspecies repulsion. F

  14. Ecological Automation Design, Extending Work Domain Analysis

    NARCIS (Netherlands)

    Amelink, M.H.J.

    2010-01-01

    In high–risk domains like aviation, medicine and nuclear power plant control, automation has enabled new capabilities, increased the economy of operation and has greatly contributed to safety. However, automation increases the number of couplings in a system, which can inadvertently lead to more com

  15. Employing Domain Knowledge for Optimizing Component Communication

    Czech Academy of Sciences Publication Activity Database

    Kit, M.; Plášil, F.; Katěna, V.; Bureš, Tomáš; Kovac, O.

    New York : ACM, 2015, s. 59-64. ISBN 978-1-4503-3471-6. [CBSE 2015. International ACM Sigsoft symposium on Component-based software engineering /18./. Montreal (CA), 04.05.2015-07.05.2015] Institutional support: RVO:67985807 Keywords : cyber-physical systems * domain knowledge * component communication Subject RIV: JC - Computer Hardware ; Software

  16. Center domains and their phenomenological consequences.

    Science.gov (United States)

    Asakawa, Masayuki; Bass, Steffen A; Müller, Berndt

    2013-05-17

    We argue that the domain structure of deconfined QCD matter, which can be inferred from the properties of the Polyakov loop, can simultaneously explain the two most prominent experimentally verified features of the quark-gluon plasma, namely its large opacity as well as its near ideal fluid properties. PMID:25167399

  17. Scalable Domain Decomposed Monte Carlo Particle Transport

    Energy Technology Data Exchange (ETDEWEB)

    O' Brien, Matthew Joseph [Univ. of California, Davis, CA (United States)

    2013-12-05

    In this dissertation, we present the parallel algorithms necessary to run domain decomposed Monte Carlo particle transport on large numbers of processors (millions of processors). Previous algorithms were not scalable, and the parallel overhead became more computationally costly than the numerical simulation.

  18. Employing domain knowledge for optimizing component communication

    Czech Academy of Sciences Publication Activity Database

    Kit, M.; Plášil, F.; Matěna, V.; Bureš, Tomáš; Kováč, O.

    New York: ACM, 2015, s. 59-64. ISBN 978-1-4503-3471-6. [CBSE 2015. International ACM SIGSOFT Symposium on Component-Based Software Engineering /18./. Montreal (CA), 04.05.2015-05.05.2015] Institutional support: RVO:67985807 Keywords : cyber-physical systems * domain knowledge * component communication Subject RIV: JC - Computer Hardware ; Software

  19. Sets of Minimal Capacity and Extremal Domains

    CERN Document Server

    Stahl, Herbert R

    2012-01-01

    Let f be a function meromorphic in a neighborhood of infinity. The central problem in the present investigation is to find the largest domain D \\subset C to which the function f can be extended in a meromorphic and singlevalued manner. 'Large' means here that the complement C\\D is minimal with respect to (logarithmic) capacity. Such extremal domains play an important role in Pad'e approximation. In the paper a unique existence theorem for extremal domains and their complementary sets of minimal capacity is proved. The topological structure of sets of minimal capacity is studied, and analytic tools for their characterization are presented; most notable are here quadratic differentials and a specific symmetry property of the Green function in the extremal domain. A local condition for the minimality of the capacity is formulated and studied. Geometric estimates for sets of minimal capacity are given. Basic ideas are illustrated by several concrete examples, which are also used in a discussion of the principal d...

  20. Behavior Domains in Theory and in Practice

    Science.gov (United States)

    McDonald, Roderick P.

    2003-01-01

    The concept of a behavior domain is a reasonable and essential foundation for psychometric work based on true score theory, the linear model of common factor analysis, and the nonlinear models of item response theory. Investigators applying these models to test data generally treat the true scores or factors or traits as abstractive psychological…

  1. PROPER HOLOMORPHIC MAPPINGS BETWEEN SOME NONSMOOTH DOMAINS

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The authors characterize the existence of proper holomorphic mapping between a kind of nonsmooth Reinhardt domains defined as Ω(p,q)=Ω(p1,……,pn,q1,……,qm) where p=(P1,……,pn) ∈ (Z+)n,q=(q1,……,qm) ∈ (Z+)m;n>1, m>1.

  2. The different roles of aggrecan interaction domains

    DEFF Research Database (Denmark)

    Aspberg, Anders

    2012-01-01

    vital in that it binds the proteoglycan to hyaluronan in ternary complex with link protein, retaining the proteoglycan in the tissue. The importance of the C-terminal G3 domain interactions has recently been emphasized by two different human hereditary disorders: autosomal recessive aggrecan...

  3. Work-domain knowledge in usability evaluation

    DEFF Research Database (Denmark)

    Følstad, Asbjørn; Hornbæk, Kasper Anders Søren

    2010-01-01

    Usability evaluation helps to determine whether interactive systems support users in their work tasks. However, knowledge about those tasks and, more generally, about the work-domain is difficult to bring to bear on the processes and outcome of usability evaluation. One way to include such work-d...... impact on the software development process. The benefits of the interpretation phases may be explained by the access these provide both to the test participants’ work-domain knowledge and to their experiences as users. .......-domain knowledge might be Cooperative Usability Testing, an evaluation method that consists of (a) interaction phases, similar to classic usability testing, and (b) interpretation phases, where the test participant and the moderator discuss incidents and experiences from the interaction phases. We have studied...... whether such interpretation phases improve the relevance of usability evaluations in the development of work-domain specific systems. The study included two development cases. We conclude that the interpretation phases generate additional insight and redesign suggestions related to observed usability...

  4. Conceptualizing Indicator Domains for Evaluating Action Research

    Science.gov (United States)

    Piggot-Irvine, Eileen; Rowe, Wendy; Ferkins, Lesley

    2015-01-01

    The focus of this paper is to share thinking about meta-level evaluation of action research (AR), and to introduce indicator domains for assessing and measuring inputs, outputs and outcomes. Meta-level and multi-site evaluation has been rare in AR beyond project implementation and participant satisfaction. The paper is the first of several…

  5. Membrane domains and polarized trafficking of sphingolipids

    NARCIS (Netherlands)

    Maier, O; Slimane, TA; Hoekstra, D

    2001-01-01

    The plasma membrane of polarized cells consists of distinct domains, the apical and basolateral membrane that are characterized by a distinct lipid and protein content. Apical protein transport is largely mediated by (glyco)sphingolipid-cholesterol enriched membrane microdomains, so called rafts. In

  6. Domain wall partition functions and KP

    International Nuclear Information System (INIS)

    We observe that the partition function of the six-vertex model on a finite square lattice with domain wall boundary conditions is (a restriction of) a KP τ function and express it as an expectation value of charged free fermions (up to an overall normalization)

  7. Domain wall partition functions and KP

    CERN Document Server

    Foda, O; Zuparic, M

    2009-01-01

    We observe that the partition function of the six vertex model on a finite square lattice with domain wall boundary conditions is (a restriction of) a KP tau function and express it as an expectation value of charged free fermions (up to an overall normalization).

  8. Microdissection of Shoot Meristem Functional Domains

    Science.gov (United States)

    The shoot apical meristem (SAM) maintains a pool of indeterminate cells within the SAM proper, while lateral organs are initiated from the SAM periphery. Laser microdissection–microarray technology was used to compare transcriptional profiles within these SAM domains to identify novel maize genes th...

  9. Domain walls. II. Baryon-number generation

    International Nuclear Information System (INIS)

    Domain walls present in the early universe due to a spontaneous breakdown of charge conjugation can leave behind net baryon number. SU/sub R/(2) instantons provide baryon nonconservation and the proton is effectively stable. Density perturbations (on scales large enough for galaxy formation) and monopole suppression can occur if walls dominate the energy density. Mechanisms for wall removal are discussed

  10. Domain Adaptation: Overfitting and Small Sample Statistics

    CERN Document Server

    Foster, Dean; Salakhutdinov, Ruslan

    2011-01-01

    We study the prevalent problem when a test distribution differs from the training distribution. We consider a setting where our training set consists of a small number of sample domains, but where we have many samples in each domain. Our goal is to generalize to a new domain. For example, we may want to learn a similarity function using only certain classes of objects, but we desire that this similarity function be applicable to object classes not present in our training sample (e.g. we might seek to learn that "dogs are similar to dogs" even though images of dogs were absent from our training set). Our theoretical analysis shows that we can select many more features than domains while avoiding overfitting by utilizing data-dependent variance properties. We present a greedy feature selection algorithm based on using T-statistics. Our experiments validate this theory showing that our T-statistic based greedy feature selection is more robust at avoiding overfitting than the classical greedy procedure.

  11. Measuring the global domain name system

    NARCIS (Netherlands)

    Casalicchio, E.; Caselli, M.; Coletta, A.; Shen, Xuemin

    2013-01-01

    The Internet is a worldwide distributed critical infrastructure, and it is composed of many vital components. While IP routing is the most important service, today the Domain Name System can be classified as the second most important, and has been defined as a critical infrastructure as well. DNS en

  12. Productivity? Domain Complexity vs. Tacit Knowledge

    DEFF Research Database (Denmark)

    Madsen, Erik Skov; Mikkelsen, Lars Lindegaard

    This paper discusses productivity in relation to tacit knowledge (which in the paper is regarded as skills, experiences, competences and attitudes) and domain complexity. The study is based on five very different case studies; three studies are conducted in Den¬mark, China, and the Czech Republic...

  13. Optimised Design of Transparent Optical Domains

    DEFF Research Database (Denmark)

    Hanik, N.; Caspar, C.; Schmidt, F.;

    2000-01-01

    Three different design concepts for transparent, dispersion compensated, optical WDM transmission links are optimised numerically and experimentally for 10 Gbit/s data rate per channel. It is shown that robust transparent domains of 1,500 km in diameter can be realised using simple design rutes....

  14. Atomic resolution imaging of ferroelectric domains

    International Nuclear Information System (INIS)

    Electron optical principles involved in obtaining atomic resolution images of ferroelectric domains are reviewed, including the methods available to obtain meaningful interpretation and analysis of the image detail in terms of the atomic structures. Recent work is concerned with establishing the relationship between the essentially static chemical nanodomains and the spatial and temporal fluctuations of the nanoscale polar domains present in the relaxor class of materials, including lead scandium tantalate (PST) and lead magnesium niobate (PMN). Correct interpretation of the images required use of Next Nearest Neighbour Ising model simulations for the chemical domain textures upon which we must superimpose the polar domain textures; an introduction to this work is presented. A thorough analysis of the atomic scale chemical inhomogeneities, based upon the HRTEM results, has lead to an improved formulation of the theory of the dielectric response of PMN and PST, which is capable to predict the observed temperature and frequency dependence. HRTEM may be combined with solid state and statistical physics principles to provide a deeper understanding of structure/property relationships. 15 refs., 6 figs

  15. Domain growth kinetics in stratifying foam films

    Science.gov (United States)

    Zhang, Yiran; Sharma, Vivek

    2015-11-01

    Baking bread, brewing cappuccino, pouring beer, washing dishes, shaving, shampooing, whipping eggs and blowing bubbles all involve creation of aqueous foam films. Typical foam films consist of two surfactant-laden surfaces that are ~ 5 nm - 10 micron apart. Sandwiched between these interfacial layers is a fluid that drains primarily under the influence of viscous and interfacial forces, including disjoining pressure. Interestingly, a layered ordering of micelles inside the foam films (thickness <100 nm) leads to a stepwise thinning phenomena called stratification, which results in a thickness-dependent variation in reflected light intensity, visualized as progressively darker shades of gray. Thinner, darker domains spontaneously grow within foam films. We show that the domain expansion dynamics exhibit two distinct growth regimes with characteristic scaling laws. Though several studies have focused on the expansion dynamics of isolated domains that exhibit a diffusion-like scaling, the change in expansion kinetics observed after domains contact with the Plateau border has not been reported and analyzed before.

  16. Backward iteration in strongly convex domains

    CERN Document Server

    Abate, Marco

    2011-01-01

    We prove that a backward orbit with bounded Kobayashi step for a hyperbolic, parabolic or strongly elliptic holomorphic self-map of a bounded strongly convex domain in d-dimensional complex Euclidean space necessarily converges to a repelling or parabolic boundary fixed point, generalizing previous results obtained by Poggi-Corradini in the unit disk and by Ostapyuk in the unit ball.

  17. JavaScript domain-driven design

    CERN Document Server

    Fehre, Philipp

    2015-01-01

    If you are an experienced JavaScript developer who wants to improve the design of his or her applications, or find yourself in a situation to implement an application in an unfamiliar domain, this book is for you. Prior knowledge of JavaScript is required and prior experience with Node.js will also be helpful.

  18. Boundary value problems on product domains

    OpenAIRE

    Ehsani, Dariush

    2005-01-01

    We consider the inhomogeneous Dirichlet problem on product domains. The main result is the asymptotic expansion of the solution in terms of increasing smoothness up to the boundary. In particular, we show the exact nature of the singularities of the solution at singularities of the boundary by constructing singular functions which make up an asymptotic expansion of the solution.

  19. Memetic Algorithms, Domain Knowledge, and Financial Investing

    Science.gov (United States)

    Du, Jie

    2012-01-01

    While the question of how to use human knowledge to guide evolutionary search is long-recognized, much remains to be done to answer this question adequately. This dissertation aims to further answer this question by exploring the role of domain knowledge in evolutionary computation as applied to real-world, complex problems, such as financial…

  20. Domain Engineering - A Software Engineering discipline in Need of Research

    DEFF Research Database (Denmark)

    Bjørner, Dines

    2000-01-01

    , and these again seem more stable than software designs. Thus, almost like the universal laws of physics, it pays off to first develop theories of domains. But domain engineering, as in fact also requirements engineering, really is in need of thoroughly researched development principles, techniques and......Before software can be developed its requirements must be stated. Before requirements can be expressed the application domain must be understood. In this paper we outline some of the basic facets of domain engineering. Domains seem, it is our experience, far more stable than computing requirements...... formal techniques. A brief example of describing stake-holder perspectives will be given - on the background of which we then proceed to survey the notions of domain intrinsics, domain support technologies, domain management & organisation, domain rules & regulations, domain human behaviour, etc. We show...

  1. Individual globular domains and domain unfolding visualized in overstretched titin molecules with atomic force microscopy.

    Directory of Open Access Journals (Sweden)

    Zsolt Mártonfalvi

    Full Text Available Titin is a giant elastomeric protein responsible for the generation of passive muscle force. Mechanical force unfolds titin's globular domains, but the exact structure of the overstretched titin molecule is not known. Here we analyzed, by using high-resolution atomic force microscopy, the structure of titin molecules overstretched with receding meniscus. The axial contour of the molecules was interrupted by topographical gaps with a mean width of 27.7 nm that corresponds well to the length of an unfolded globular (immunoglobulin and fibronectin domain. The wide gap-width distribution suggests, however, that additional mechanisms such as partial domain unfolding and the unfolding of neighboring domain multimers may also be present. In the folded regions we resolved globules with an average spacing of 5.9 nm, which is consistent with a titin chain composed globular domains with extended interdomain linker regions. Topographical analysis allowed us to allocate the most distal unfolded titin region to the kinase domain, suggesting that this domain systematically unfolds when the molecule is exposed to overstretching forces. The observations support the prediction that upon the action of stretching forces the N-terminal ß-sheet of the titin kinase unfolds, thus exposing the enzyme's ATP-binding site and hence contributing to the molecule's mechanosensory function.

  2. Simplicity and Specificity in Language: Domain-General Biases Have Domain-Specific Effects.

    Science.gov (United States)

    Culbertson, Jennifer; Kirby, Simon

    2015-01-01

    The extent to which the linguistic system-its architecture, the representations it operates on, the constraints it is subject to-is specific to language has broad implications for cognitive science and its relation to evolutionary biology. Importantly, a given property of the linguistic system can be "specific" to the domain of language in several ways. For example, if the property evolved by natural selection under the pressure of the linguistic function it serves then the property is domain-specific in the sense that its design is tailored for language. Equally though, if that property evolved to serve a different function or if that property is domain-general, it may nevertheless interact with the linguistic system in a way that is unique. This gives a second sense in which a property can be thought of as specific to language. An evolutionary approach to the language faculty might at first blush appear to favor domain-specificity in the first sense, with individual properties of the language faculty being specifically linguistic adaptations. However, we argue that interactions between learning, culture, and biological evolution mean any domain-specific adaptations that evolve will take the form of weak biases rather than hard constraints. Turning to the latter sense of domain-specificity, we highlight a very general bias, simplicity, which operates widely in cognition and yet interacts with linguistic representations in domain-specific ways. PMID:26793132

  3. Simplicity and Specificity in Language: Domain general biases have domain specific effects

    Directory of Open Access Journals (Sweden)

    Jennifer eCulbertson

    2016-01-01

    Full Text Available The extent to which the linguistic system—its architecture, the representations it operates on, the constraints it is subject to—is specific to language has broad implications for cognitive science and its relation to evolutionary biology. Importantly, a given property of the linguistic system can be specific to the domain of language in several ways. For example, if the property evolved by natural selection under the pressure of the linguistic function it serves then the property is domain­-specific in the sense that its design is tailored for language. Equally though, if that property evolved to serve a different function or if that property is domain-general, it may nevertheless interact with the linguistic system in a way that is unique. This gives a second sense in which a property can be thought of as specific to language. An evolutionary approach to the language faculty might at first blush appear to favor domain­-specificity in the first sense, with individual properties of the language faculty being specifically linguistic adaptations. However, we argue that interactions between learning, culture and biological evolution mean any domain-specific adaptations that evolve will take the form of weak biases rather than hard constraints. Turning to the latter sense of domain-specificity, we highlight a very general bias, simplicity, which operates widely in cognition and yet interacts with linguistic representations in a domain-­specific way.

  4. Domain Representable Spaces Defined by Strictly Positive Induction

    OpenAIRE

    Køber, Petter Kristian

    2010-01-01

    Recursive domain equations have natural solutions. In particular there are domains defined by strictly positive induction. The class of countably based domains gives a computability theory for possibly non-countably based topological spaces. A $ qcb_{0} $ space is a topological space characterized by its strong representability over domains. In this paper, we study strictly positive inductive definitions for $ qcb_{0} $ spaces by means of domain representations, i.e. we show that there exists...

  5. SINGLE IMAGE SUPER RESOLUTION IN SPATIAL AND WAVELET DOMAIN

    OpenAIRE

    Sapan Naik; Nikunj Patel

    2013-01-01

    Recently single image super resolution is very important research area to generate high-resolution image from given low-resolution image. Algorithms of single image resolution are mainly based on wavelet domain and spatial domain. Filter’s support to model the regularity of natural images is exploited in wavelet domain while edges of images get sharp during up sampling in spatial domain. Here single image super resolution algorithm is presented which based on both spatial and wavelet domain a...

  6. A mixed finite element domain decomposition method for nearly elastic wave equations in the frequency domain

    Energy Technology Data Exchange (ETDEWEB)

    Feng, Xiaobing [Univ. of Tennessee, Knoxville, TN (United States)

    1996-12-31

    A non-overlapping domain decomposition iterative method is proposed and analyzed for mixed finite element methods for a sequence of noncoercive elliptic systems with radiation boundary conditions. These differential systems describe the motion of a nearly elastic solid in the frequency domain. The convergence of the iterative procedure is demonstrated and the rate of convergence is derived for the case when the domain is decomposed into subdomains in which each subdomain consists of an individual element associated with the mixed finite elements. The hybridization of mixed finite element methods plays a important role in the construction of the discrete procedure.

  7. THE OVERLAPPING DOMAIN DECOMPOSITION METHOD FOR HARMONIC EQUATION OVER EXTERIOR THREE-DIMENSIONAL DOMAIN

    Institute of Scientific and Technical Information of China (English)

    Ji-ming Wu; De-hao Yu

    2000-01-01

    In this paper, the overlapping domain decomposition method, which is based on the natural boundary reduction[1] and first suggested in [2], is applied to slove the exterior boundary value problem of harmonic equation over three-dimensional domain. The convergence and error estimates both for the continuous case and the discrete case are given. The contraction factor for the exterior spherical domain is also discussed. Moreover, numerical results are given which show that the accuracy and the convergence are in accord with the theoretical analyses.

  8. Domain-and species-specific monoclonal antibodies recognize the Von Willebrand Factor-C domain of CCN5

    OpenAIRE

    Wei, Lan; McKeon, Frank; Russo, Joshua W.; Lemire, Joan; Castellot, John

    2009-01-01

    The CCN family of proteins typically consists of four distinct peptide domains: an insulin-like growth factor binding protein-type (IGFBP) domain, a Von Willebrand Factor C (VWC) domain, a thrombospondin type 1 repeat (TSP1) domain, and a carboxy-terminal (CT) domain. The six family members participate in many processes, including proliferation, motility, cell-matrix signaling, angiogenesis, and wound healing. Accumulating evidence suggests that truncated and alternatively spliced isoforms ar...

  9. High order expanding domain methods for the solution of Poisson's equation in infinite domains

    Science.gov (United States)

    Anderson, Christopher R.

    2016-06-01

    In this paper we present a discrete Fourier transform based procedure to evaluate the infinite domain solution of Poisson's equation at points in a rectangular computational region. The numerical procedure is a modification of an "expanding domain" type method where one obtains approximations of increasing accuracy by expanding the computational domain. The modification presented here is one that leads to approximations that converge with high order rates of convergence with respect to domain size. Spectrally accurate approximations are used to approximate differential operators and so the method possesses very high rates of convergence with respect to mesh size as well. Computational results on both two and three dimensional test problems are presented that demonstrate the accuracy and computational efficiency of the procedure.

  10. Semi-Supervised Single- and Multi-Domain Regression with Multi-Domain Training

    CERN Document Server

    Michaeli, Tomer; Sapiro, Guillermo

    2012-01-01

    We address the problems of multi-domain and single-domain regression based on distinct and unpaired labeled training sets for each of the domains and a large unlabeled training set from all domains. We formulate these problems as a Bayesian estimation with partial knowledge of statistical relations. We propose a worst-case design strategy and study the resulting estimators. Our analysis explicitly accounts for the cardinality of the labeled sets and includes the special cases in which one of the labeled sets is very large or, in the other extreme, completely missing. We demonstrate our estimators in the context of removing expressions from facial images and in the context of audio-visual word recognition, and provide comparisons to several recently proposed multi-modal learning algorithms.

  11. A segmental labeling strategy for unambiguous determination of domain–domain interactions of large multi-domain proteins

    International Nuclear Information System (INIS)

    NMR structural determination of large multi-domain proteins is a challenging task due to significant spectral overlap with a particular difficulty in unambiguous identification of domain–domain interactions. Segmental labeling is a NMR strategy that allows for isotopically labeling one domain and leaves the other domain unlabeled. This significantly simplifies spectral overlaps and allows for quick identification of domain–domain interaction. Here, a novel segmental labeling strategy is presented for detection of inter-domain NOEs. To identify domain–domain interactions in human apolipoprotein E (apoE), a multi-domain, 299-residues α-helical protein, on-column expressed protein ligation was utilized to generate a segmental-labeled apoE samples in which the N-terminal (NT-) domain was 2H(99%)/15N-labeled whereas the C-terminal (CT-) domain was either 15N- or 15N/13C-labeled. 3-D 15N-edited NOESY spectra of these segmental-labeled apoE samples allow for direct observation of the inter-domain NOEs between the backbone amide protons of the NT-domain and the aliphatic protons of the CT-domain. This straightforward approach permits unambiguous identification of 78 inter-domain NOEs, enabling accurate definition of the relative positions of both the NT- and the CT-domains and determination of the NMR structure of apoE.

  12. Quantifying information transfer by protein domains: Analysis of the Fyn SH2 domain structure

    Directory of Open Access Journals (Sweden)

    Serrano Luis

    2008-10-01

    Full Text Available Abstract Background Efficient communication between distant sites within a protein is essential for cooperative biological response. Although often associated with large allosteric movements, more subtle changes in protein dynamics can also induce long-range correlations. However, an appropriate formalism that directly relates protein structural dynamics to information exchange between functional sites is still lacking. Results Here we introduce a method to analyze protein dynamics within the framework of information theory and show that signal transduction within proteins can be considered as a particular instance of communication over a noisy channel. In particular, we analyze the conformational correlations between protein residues and apply the concept of mutual information to quantify information exchange. Mapping out changes of mutual information on the protein structure then allows visualizing how distal communication is achieved. We illustrate the approach by analyzing information transfer by the SH2 domain of Fyn tyrosine kinase, obtained from Monte Carlo dynamics simulations. Our analysis reveals that the Fyn SH2 domain forms a noisy communication channel that couples residues located in the phosphopeptide and specificity binding sites and a number of residues at the other side of the domain near the linkers that connect the SH2 domain to the SH3 and kinase domains. We find that for this particular domain, communication is affected by a series of contiguous residues that connect distal sites by crossing the core of the SH2 domain. Conclusion As a result, our method provides a means to directly map the exchange of biological information on the structure of protein domains, making it clear how binding triggers conformational changes in the protein structure. As such it provides a structural road, next to the existing attempts at sequence level, to predict long-range interactions within protein structures.

  13. Thermal Loss of High-Q Antennas in Time Domain vs. Frequency Domain Solver

    DEFF Research Database (Denmark)

    Bahramzy, Pevand; Pedersen, Gert Frølund

    High-Q structures pose great challenges to their loss simulations in Time Domain Solvers (TDS). Therefore, in this work the thermal loss of high-Q antennas is calculated both in TDS and Frequency Domain Solver (FDS), which are then compared with each other and with the actual measurements. The...... thermal loss calculation in FDS is shown to be more accurate for high-Q antennas....

  14. Simplicity and Specificity in Language: Domain general biases have domain specific effects

    OpenAIRE

    Jennifer eCulbertson; Simon eKirby

    2016-01-01

    The extent to which the linguistic system—its architecture, the representations it operates on, the constraints it is subject to—is specific to language has broad implications for cognitive science and its relation to evolutionary biology. Importantly, a given property of the linguistic system can be specific to the domain of language in several ways. For example, if the property evolved by natural selection under the pressure of the linguistic function it serves then the property is domain­-...

  15. Simplicity and Specificity in Language: Domain-General Biases Have Domain-Specific Effects

    OpenAIRE

    Culbertson, Jennifer; Kirby, Simon

    2016-01-01

    The extent to which the linguistic system—its architecture, the representations it operates on, the constraints it is subject to—is specific to language has broad implications for cognitive science and its relation to evolutionary biology. Importantly, a given property of the linguistic system can be “specific” to the domain of language in several ways. For example, if the property evolved by natural selection under the pressure of the linguistic function it serves then the property is domain...

  16. Diligence of Domain Engineering in Accounting Management System

    Directory of Open Access Journals (Sweden)

    Mukesh Arya

    2012-07-01

    Full Text Available This paper presents on domain feature modeling, domain architecture design and domain implementation in an enterprise. This paper demonstrates the accounting management feature modeling based on the extended (Feature-Oriented Domain Analysis FODA method and system architecture of accounting management domain, integrates Aspect Object Oriented Programming technology with domain implementation, and designs a whippersnapper AOP framework based on the object proxy pattern to separates crosscutting concerns in the domain implementation phrase. Research result shows this method can effectively seal insulate and abstract variability in requirements of accounting management domain, instruct the designing and implementation of accounting management components, get the requirement of software reuse, resource sharing and collaboration in accounting management domain.

  17. Fast domain wall dynamics in amorphous and nanocrystalline magnetic microwires

    Energy Technology Data Exchange (ETDEWEB)

    Varga, R., E-mail: rvarga@upjs.sk [Institute of Physics, Faculty of Science, UPJS, Park Angelinum 9, 041 54, Kosice (Slovakia); Klein, P.; Richter, K. [Institute of Physics, Faculty of Science, UPJS, Park Angelinum 9, 041 54, Kosice (Slovakia); Zhukov, A. [Dept. Fisica de Materiales, Fac. Quimica, UPV/EHU, San Sebastian (Spain); Vazquez, M. [Instituto de Ciencia de Materiales de Madrid, CSIC, Sor Juana Ines de la Cruz 3, 28049 Cantoblanco, Madrid (Spain)

    2012-10-15

    We have studied the effect of thermal treatment on the domain wall dynamics of FeSiB and FeCoMoB microwires. It was shown that annealing in transversal magnetic field increases the domain wall mobility as well as the domain wall velocity. Annealing under the tensile stress hinders the appearance of the monodomain structure but application of tensile stress leads to the magnetic bistability having the domain wall mobility twice higher that in as-cast state. Further increase of the tensile stress reduces the domain wall mobility but the domain wall velocity increases as a result of the decrease of critical propagation field. Annealing of the FeCoMoB microwire by Joule heating leads to introduction of the circular anisotropy that favors the vortex domain wall. Such treatment increases the domain wall mobility as well as the maximum domain wall velocity.

  18. Ribosomal small subunit domains radiate from a central core

    Science.gov (United States)

    Gulen, Burak; Petrov, Anton S.; Okafor, C. Denise; Vander Wood, Drew; O'Neill, Eric B.; Hud, Nicholas V.; Williams, Loren Dean

    2016-02-01

    The domain architecture of a large RNA can help explain and/or predict folding, function, biogenesis and evolution. We offer a formal and general definition of an RNA domain and use that definition to experimentally characterize the rRNA of the ribosomal small subunit. Here the rRNA comprising a domain is compact, with a self-contained system of molecular interactions. A given rRNA helix or stem-loop must be allocated uniquely to a single domain. Local changes such as mutations can give domain-wide effects. Helices within a domain have interdependent orientations, stabilities and interactions. With these criteria we identify a core domain (domain A) of small subunit rRNA. Domain A acts as a hub, linking the four peripheral domains and imposing orientational and positional restraints on the other domains. Experimental characterization of isolated domain A, and mutations and truncations of it, by methods including selective 2‧OH acylation analyzed by primer extension and circular dichroism spectroscopy are consistent with our architectural model. The results support the utility of the concept of an RNA domain. Domain A, which exhibits structural similarity to tRNA, appears to be an essential core of the small ribosomal subunit.

  19. PX domain and CD domain play different roles in localization and vacuolation of Sorting Nexin 10

    Institute of Scientific and Technical Information of China (English)

    YAO Dong; WU Bin; QIN BaoMing; PEI DuanQing

    2009-01-01

    Sorting nexins (SNXs) are PX domain containing proteins and essential for intracellular protein sorting,trafficking and signal transduction.The PX domains of SNXs can bind to various phosphorelated phosphoinositides (Pls) and target the host proteins to endosomes.Recently,we have reported that overexpression of SNX10 in mammalian cells could induce giant vacuoles.In this study,we aimed to identify regions in SNX10 critical for the vacuolation activity.We found that both the PX domain and the CD1 region were essential for vacuolation.We provided evidence that the PX domain was able to specifically bind to Ptdlns(3)P and target SNX10 to endosomes.A mutation in the β1 region of the PX domain (V15A) disrupted the Ptdlns(3)P binding ability and the endosomal localization of SNX10.However,correct subcellular localization alone was not sufficient for SNX10 to induce vacuoles.We found that the CD1 region,which was not required for the localization,was indispensable for the vacuolation activity of SNX10.In summary,both the PX domain and the CD1 region are necessary for SNX10 to induce vacuoles but they play different roles in this process.

  20. Skyrmion domain wall collision and domain wall-gated skyrmion logic

    Science.gov (United States)

    Xing, Xiangjun; Pong, Philip W. T.; Zhou, Yan

    2016-08-01

    Skyrmions and domain walls are significant spin textures of great technological relevance to magnetic memory and logic applications, where they can be used as carriers of information. The unique topology of skyrmions makes them display emergent dynamical properties as compared with domain walls. Some studies have demonstrated that the two topologically inequivalent magnetic objects could be interconverted by using cleverly designed geometric structures. Here, we numerically address the skyrmion domain wall collision in a magnetic racetrack by introducing relative motion between the two objects based on a specially designed junction. An electric current serves as the driving force that moves a skyrmion toward a trapped domain wall pair. We see different types of collision dynamics depending on the driving parameters. Most importantly, the modulation of skyrmion transport using domain walls is realized in this system, allowing a set of domain wall-gated logical NOT, NAND, and NOR gates to be constructed. This work provides a skyrmion-based spin-logic architecture that is fully compatible with racetrack memories.

  1. Broadband Beamspace DOA Estimation: Frequency-Domain and Time-Domain Processing Approaches

    Directory of Open Access Journals (Sweden)

    Yan Shefeng

    2007-01-01

    Full Text Available Frequency-domain and time-domain processing approaches to direction-of-arrival (DOA estimation for multiple broadband far field signals using beamspace preprocessing structures are proposed. The technique is based on constant mainlobe response beamforming. A set of frequency-domain and time-domain beamformers with constant (frequency independent mainlobe response and controlled sidelobes is designed to cover the spatial sector of interest using optimal array pattern synthesis technique and optimal FIR filters design technique. These techniques lead the resulting beampatterns higher mainlobe approximation accuracy and yet lower sidelobes. For the scenario of strong out-of-sector interfering sources, our approaches can form nulls or notches in the direction of them and yet guarantee that the mainlobe response of the beamformers is constant over the design band. Numerical results show that the proposed time-domain processing DOA estimator has comparable performance with the proposed frequency-domain processing method, and that both of them are able to resolve correlated source signals and provide better resolution at lower signal-to-noise ratio (SNR and lower root-mean-square error (RMSE of the DOA estimate compared with the existing method. Our beamspace DOA estimators maintain good DOA estimation and spatial resolution capability in the scenario of strong out-of-sector interfering sources.

  2. Domain Decomposition Methods for Hyperbolic Problems

    Indian Academy of Sciences (India)

    Pravir Dutt; Subir Singh Lamba

    2009-04-01

    In this paper a method is developed for solving hyperbolic initial boundary value problems in one space dimension using domain decomposition, which can be extended to problems in several space dimensions. We minimize a functional which is the sum of squares of the 2 norms of the residuals and a term which is the sum of the squares of the 2 norms of the jumps in the function across interdomain boundaries. To make the problem well posed the interdomain boundaries are made to move back and forth at alternate time steps with sufficiently high speed. We construct parallel preconditioners and obtain error estimates for the method. The Schwarz waveform relaxation method is often employed to solve hyperbolic problems using domain decomposition but this technique faces difficulties if the system becomes characteristic at the inter-element boundaries. By making the inter-element boundaries move faster than the fastest wave speed associated with the hyperbolic system we are able to overcome this problem.

  3. Diastereomeric liquid crystal domains at the mesoscale

    Science.gov (United States)

    Chen, Dong; Tuchband, Michael R.; Horanyi, Balazs; Korblova, Eva; Walba, David M.; Glaser, Matthew A.; Maclennan, Joseph E.; Clark, Noel A.

    2015-08-01

    In many technologies used to achieve separation of enantiomers, chiral selectors are designed to display differential affinity for the two enantiomers of a chiral compound. Such complexes are diastereomeric, differing in structure and free energy for the two enantiomers and enabling chiral discrimination. Here we present evidence for strong diastereomeric interaction effects at the mesoscale, manifested in chiral liquid crystal guest materials confined in a chiral, nanoporous network of semi-crystalline helical nanofilaments. The nanoporous host is itself an assembly of achiral, bent-core liquid crystal molecules that phase-separate into a conglomerate of 100 micron-scale, helical nanofilament domains that differ in structure only in the handedness of their homogeneous chirality. With the inclusion of a homochiral guest liquid crystal, these enantiomeric domains become diastereomeric, exhibiting unexpected and markedly different mesoscale structures and orientation transitions producing optical effects in which chirality has a dominant role.

  4. Dynamics of Nonlinear Waves on Bounded Domains

    CERN Document Server

    Maliborski, Maciej

    2016-01-01

    This thesis is concerned with dynamics of conservative nonlinear waves on bounded domains. In general, there are two scenarios of evolution. Either the solution behaves in an oscillatory, quasiperiodic manner or the nonlinear effects cause the energy to concentrate on smaller scales leading to a turbulent behaviour. Which of these two possibilities occurs depends on a model and the initial conditions. In the quasiperiodic scenario there exist very special time-periodic solutions. They result for a delicate balance between dispersion and nonlinear interaction. The main body of this dissertation is concerned with construction (by means of perturbative and numerical methods) of time-periodic solutions for various nonlinear wave equations on bounded domains. While turbulence is mainly associated with hydrodynamics, recent research in General Relativity has also revealed turbulent phenomena. Numerical studies of a self-gravitating massless scalar field in spherical symmetry gave evidence that anti-de Sitter space ...

  5. Nodal domain distributions for quantum maps

    International Nuclear Information System (INIS)

    The statistics of the nodal lines and nodal domains of the eigenfunctions of quantum billiards have recently been observed to be fingerprints of the chaoticity of the underlying classical motion by Blum et al (2002 Phys. Rev. Lett. 88 114101) and by Bogomolny and Schmit (2002 Phys. Rev. Lett. 88 114102). These statistics were shown to be computable from the random wave model of the eigenfunctions. We here study the analogous problem for chaotic maps whose phase space is the two-torus. We show that the distributions of the numbers of nodal points and nodal domains of the eigenvectors of the corresponding quantum maps can be computed straightforwardly and exactly using random matrix theory. We compare the predictions with the results of numerical computations involving quantum perturbed cat maps. (letter to the editor)

  6. Multiple Shooting and Time Domain Decomposition Methods

    CERN Document Server

    Geiger, Michael; Körkel, Stefan; Rannacher, Rolf

    2015-01-01

    This book offers a comprehensive collection of the most advanced numerical techniques for the efficient and effective solution of simulation and optimization problems governed by systems of time-dependent differential equations. The contributions present various approaches to time domain decomposition, focusing on multiple shooting and parareal algorithms.  The range of topics covers theoretical analysis of the methods, as well as their algorithmic formulation and guidelines for practical implementation. Selected examples show that the discussed approaches are mandatory for the solution of challenging practical problems. The practicability and efficiency of the presented methods is illustrated by several case studies from fluid dynamics, data compression, image processing and computational biology, giving rise to possible new research topics.  This volume, resulting from the workshop Multiple Shooting and Time Domain Decomposition Methods, held in Heidelberg in May 2013, will be of great interest to applied...

  7. LHC RF System Time-Domain Simulation

    Energy Technology Data Exchange (ETDEWEB)

    Mastorides, T.; Rivetta, C.; /SLAC

    2010-09-14

    Non-linear time-domain simulations have been developed for the Positron-Electron Project (PEP-II) and the Large Hadron Collider (LHC). These simulations capture the dynamic behavior of the RF station-beam interaction and are structured to reproduce the technical characteristics of the system (noise contributions, non-linear elements, and more). As such, they provide useful results and insight for the development and design of future LLRF feedback systems. They are also a valuable tool for the study of diverse longitudinal beam dynamics effects such as coupled-bunch impedance driven instabilities and single bunch longitudinal emittance growth. Results from these studies and related measurements from PEP-II and LHC have been presented in multiple places. This report presents an example of the time-domain simulation implementation for the LHC.

  8. Modeling Network Traffic in Wavelet Domain

    Directory of Open Access Journals (Sweden)

    Sheng Ma

    2004-12-01

    Full Text Available This work discovers that although network traffic has the complicated short- and long-range temporal dependence, the corresponding wavelet coefficients are no longer long-range dependent. Therefore, a "short-range" dependent process can be used to model network traffic in the wavelet domain. Both independent and Markov models are investigated. Theoretical analysis shows that the independent wavelet model is sufficiently accurate in terms of the buffer overflow probability for Fractional Gaussian Noise traffic. Any model, which captures additional correlations in the wavelet domain, only improves the performance marginally. The independent wavelet model is then used as a unified approach to model network traffic including VBR MPEG video and Ethernet data. The computational complexity is O(N for developing such wavelet models and generating synthesized traffic of length N, which is among the lowest attained.

  9. Language Modelling For Task-Oriented Domains

    CERN Document Server

    Popovici, C; Popovici, Cosmin; Baggia, Paolo

    1997-01-01

    This paper is focused on the language modelling for task-oriented domains and presents an accurate analysis of the utterances acquired by the Dialogos spoken dialogue system. Dialogos allows access to the Italian Railways timetable by using the telephone over the public network. The language modelling aspects of specificity and behaviour to rare events are studied. A technique for getting a language model more robust, based on sentences generated by grammars, is presented. Experimental results show the benefit of the proposed technique. The increment of performance between language models created using grammars and usual ones, is higher when the amount of training material is limited. Therefore this technique can give an advantage especially for the development of language models in a new domain.

  10. Inflationary power asymmetry from primordial domain walls

    CERN Document Server

    Jazayeri, Sadra; Firouzjahi, Hassan; Solomon, Adam R; Wang, Yi

    2014-01-01

    We study the asymmetric primordial fluctuations in a model of inflation in which translational invariance is broken by a domain wall. We calculate the corrections to the power spectrum of curvature perturbations; they are anisotropic and contain dipole, quadrupole, and higher multipoles with non-trivial scale-dependent amplitudes. Inspired by observations of these multipole asymmetries in terms of two-point correlations and variance in real space, we demonstrate that this model can explain the observed anomalous power asymmetry of the cosmic microwave background (CMB) sky, including its characteristic feature that the dipole dominates over higher multipoles. We test the viability of the model and place approximate constraints on its parameters by using observational values of dipole, quadrupole, and octopole amplitudes of the asymmetry measured by a local-variance estimator. We find that a configuration of the model in which the CMB sphere does not intersect the domain wall during inflation provides a good fi...

  11. Inhomogeneous rotation in ferroelastic domain patterns

    Science.gov (United States)

    Jacobs, A. E.; Curnoe, S. H.; Desai, R. C.

    2004-03-01

    We study static, two-dimensional domain patterns obtained by numerical minimization of the strain energy for proper triangular→centered-rectangular (T-CR) and square→rectangular ferroelastics. Applications are made to hexagonal→orthorhombic and related materials (lead orthovanadate, Mg_3Cd, Ta_4N, etc) and YBa_2Cu_3O_7-δ. Examinatin of the local rotation, the local energy density and the non-order-parameter strains reveals wedge and other disclinations responsible for the complexity of the patterns. The rotation might be observed in birefringence imaging. We report also unusual structures obtained near Tc in T-CR systems, including trapped high-T phase and pencil-like domains.

  12. Myonuclear domains in muscle adaptation and disease

    Science.gov (United States)

    Allen, D. L.; Roy, R. R.; Edgerton, V. R.

    1999-01-01

    Adult skeletal muscle fibers are among the few cell types that are truly multinucleated. Recently, evidence has accumulated supporting a role for the modulation of myonuclear number during muscle remodeling in response to injury, adaptation, and disease. These studies have demonstrated that muscle hypertrophy is associated with, and is dependent on, the addition of newly formed myonuclei via the fusion of myogenic cells to the adult myofiber, whereas muscle atrophy and disease appear to be associated with the loss of myonuclei, possibly through apoptotic-like mechanisms. Moreover, these studies also have demonstrated that myonuclear domain size, i. e., the amount of cytoplasm per myonucleus, is unchanged following the acute phase of hypertrophy but is reduced following atrophy. Together these data demonstrate that modulation of myonuclear number or myonuclear domain size (or both) is a mechanism contributing to the remodeling of adult skeletal muscle in response to alterations in the level of normal neuromuscular activity. Copyright 1999 John Wiley & Sons, Inc.

  13. Digital Switching in the Quantum Domain

    CERN Document Server

    Tsai, I M

    2002-01-01

    In this paper, we present an architecture and implementation algorithm such that digital data can be switched in the quantum domain. First we define the connection digraph which can be used to describe the behavior of a switch at a given time, then we show how a connection digraph can be implemented using elementary quantum gates. The proposed mechanism supports unicasting as well as multicasting, and is strict-sense non-blocking. It can be applied to perform either circuit switching or packet switching. Compared with a traditional space or time domain switch, the proposed switching mechanism is more scalable. Assuming an n-by-n quantum switch, the space consumption grows linearly, i.e. O(n), while the time complexity is O(1) for unicasting, and O(log n) for multicasting. Based on these advantages, a high throughput switching device can be built simply by increasing the number of I/O ports.

  14. Structural and Histone Binding Ability Characterizations of Human PWWP Domains

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Hong; Zeng, Hong; Lam, Robert; Tempel, Wolfram; Amaya, Maria F.; Xu, Chao; Dombrovski, Ludmila; Qiu, Wei; Wang, Yanming; Min, Jinrong (Toronto); (Penn)

    2013-09-25

    The PWWP domain was first identified as a structural motif of 100-130 amino acids in the WHSC1 protein and predicted to be a protein-protein interaction domain. It belongs to the Tudor domain 'Royal Family', which consists of Tudor, chromodomain, MBT and PWWP domains. While Tudor, chromodomain and MBT domains have long been known to bind methylated histones, PWWP was shown to exhibit histone binding ability only until recently. The PWWP domain has been shown to be a DNA binding domain, but sequence analysis and previous structural studies show that the PWWP domain exhibits significant similarity to other 'Royal Family' members, implying that the PWWP domain has the potential to bind histones. In order to further explore the function of the PWWP domain, we used the protein family approach to determine the crystal structures of the PWWP domains from seven different human proteins. Our fluorescence polarization binding studies show that PWWP domains have weak histone binding ability, which is also confirmed by our NMR titration experiments. Furthermore, we determined the crystal structures of the BRPF1 PWWP domain in complex with H3K36me3, and HDGF2 PWWP domain in complex with H3K79me3 and H4K20me3. PWWP proteins constitute a new family of methyl lysine histone binders. The PWWP domain consists of three motifs: a canonical {beta}-barrel core, an insertion motif between the second and third {beta}-strands and a C-terminal {alpha}-helix bundle. Both the canonical {beta}-barrel core and the insertion motif are directly involved in histone binding. The PWWP domain has been previously shown to be a DNA binding domain. Therefore, the PWWP domain exhibits dual functions: binding both DNA and methyllysine histones.

  15. Time Domain Modelling of a Reciprocating Engine

    Science.gov (United States)

    Li, H.; Stone, B. J.

    1999-01-01

    This paper describes the application of a time domain systems approach to the modelling of a reciprocating engine. The engine model includes the varying inertia effects resulting from the motion of the piston and con-rod. The cylinder pressure measured under operating conditions is used to force the model and the resulting motion compared with the measured response. The results obtained indicate that the model is very good.

  16. Evaluating Term Extraction Methods for Domain Analysis

    OpenAIRE

    Nemallapudi, Chaitanya

    2010-01-01

    This study compared the vocabularies created by various domain experts and the source documents selected by them to create the vocabulary. The results indicate that there is similarity among the vocabularies created and the source documents selected. Also, the relationship between the overlap scores of vocabularies created and overlap scores of source documents selected was tested and it was observed that no significant relation exists between them. In addition, the variability of the overlap...

  17. Music objectives planning in prevailing psychomotor domain

    OpenAIRE

    Sicherl Kafol, Barbara; Denac, Olga; Denac, Jerneja; Zalar, Konstanca

    2014-01-01

    Th e paper presents the results of a study in which we analysed planning of musical objectives in the psychomotor domain prepared by 372 Slovenian general education teachers. Th e research results showed high share of objectives pertaining to the taxonomy category of speech behaviours, which was followed by the categories of gross bodily movements, fi nely coordinated movements and non-verbal communication. Th e above facts confi rm that music objectives can be classifi ed i...

  18. Learning Symbolic Models of Stochastic Domains

    OpenAIRE

    Kaelbling, L. P.; Pasula, H. M.; Zettlemoyer, L. S.

    2011-01-01

    In this article, we work towards the goal of developing agents that can learn to act in complex worlds. We develop a probabilistic, relational planning rule representation that compactly models noisy, nondeterministic action effects, and show how such rules can be effectively learned. Through experiments in simple planning domains and a 3D simulated blocks world with realistic physics, we demonstrate that this learning algorithm allows agents to effectively model world dynamics.

  19. Inverse Reinforcement Learning in Relational Domains

    OpenAIRE

    Munzer, Thibaut; Piot, Bilal; Geist, Matthieu; Pietquin, Olivier; Lopes, Manuel

    2015-01-01

    In this work, we introduce the first approach to the Inverse Reinforcement Learning (IRL) problem in relational domains. IRL has been used to recover a more compact representation of the expert policy leading to better generalization performances among different contexts. On the other hand, rela-tional learning allows representing problems with a varying number of objects (potentially infinite), thus provides more generalizable representations of problems and skills. We show how these differe...

  20. Metrology for terahertz time-domain spectrometers

    Science.gov (United States)

    Molloy, John F.; Naftaly, Mira

    2015-12-01

    In recent years the terahertz time-domain spectrometer (THz TDS) [1] has emerged as a key measurement device for spectroscopic investigations in the frequency range of 0.1-5 THz. To date, almost every type of material has been studied using THz TDS, including semiconductors, ceramics, polymers, metal films, liquid crystals, glasses, pharmaceuticals, DNA molecules, proteins, gases, composites, foams, oils, and many others. Measurements with a TDS are made in the time domain; conversion from the time domain data to a frequency spectrum is achieved by applying the Fourier Transform, calculated numerically using the Fast Fourier Transform (FFT) algorithm. As in many other types of spectrometer, THz TDS requires that the sample data be referenced to similarly acquired data with no sample present. Unlike frequency-domain spectrometers which detect light intensity and measure absorption spectra, a TDS records both amplitude and phase information, and therefore yields both the absorption coefficient and the refractive index of the sample material. The analysis of the data from THz TDS relies on the assumptions that: a) the frequency scale is accurate; b) the measurement of THz field amplitude is linear; and c) that the presence of the sample does not affect the performance characteristics of the instrument. The frequency scale of a THz TDS is derived from the displacement of the delay line; via FFT, positioning errors may give rise to frequency errors that are difficult to quantify. The measurement of the field amplitude in a THz TDS is required to be linear with a dynamic range of the order of 10 000. And attention must be given to the sample positioning and handling in order to avoid sample-related errors.

  1. Crystal Structure of the Dynein Motor Domain

    OpenAIRE

    Carter, Andrew P.; Cho, Carol; Jin, Lan; Vale, Ronald D.

    2011-01-01

    Dyneins are microtubule-based motor proteins that power ciliary beating, transport intracellular cargos, and help to construct the mitotic spindle. Evolved from ring-shaped hexameric AAA-family adenosine triphosphatases (ATPases), dynein’s large size and complexity have posed challenges for understanding its structure and mechanism. Here, we present a 6 angstrom crystal structure of a functional dimer of two ~300-kilodalton motor domains of yeast cytoplasmic dynein. The structure reveals an u...

  2. Frequency-Domain Robust Control Toolbox

    OpenAIRE

    Karimi, Alireza

    2013-01-01

    A new frequency-domain robust control toolbox is introduced and compared with some features of the robust control toolbox of Matlab. A summary of the theoretical background for H-infinity controller design using the spectral models is given. The main advantage of this toolbox is that almost all types of model uncertainties like unmodelled dynamics, multimodel uncertainty, spectral uncertainty and parametric uncertainty can be taken into account without conservatism. As a result, the uncertain...

  3. 2015 Cross-Domain Deterrence Seminar Bibliography

    Energy Technology Data Exchange (ETDEWEB)

    Juarez, Anthony [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-02-04

    In November 2015, the Center for Global Security Research, NSO, and Global Security program jointly sponsored a seminar investigating questions related to cross-domain deterrence at Lawrence Livermore National Laboratory. At the seminar, experts were asked to moderate discussion based on the four topics below. For each of these topics, we have compiled a short list of literature that will help analysts develop a baseline understanding of the issue.

  4. Analysis domain model for shared virtual environments

    OpenAIRE

    Oliveira, M.; Jordan, J; J Pereira; Jorge, J; Steed, A.

    2009-01-01

    The field of shared virtual environments, which also encompasses online games and social 3D environments, has a system landscape consisting of multiple solutions that share great functional overlap. However, there is little system interoperability between the different solutions. A shared virtual environment has an associated problem domain that is highly complex raising difficult challenges to the development process, starting with the architectural design of the underlying system. Thi...

  5. Time-Domain Filtering of Metasurfaces

    OpenAIRE

    Hiroki Wakatsuchi

    2015-01-01

    In general electromagnetic response of each material to a continuous wave does not vary in time domain if the frequency component remains the same. Recently, it turned out that integrating several circuit elements including schottky diodes with periodically metallised surfaces, or the so-called metasurfaces, leads to selectively absorbing specific types of waveforms or pulse widths even at the same frequency. These waveform-selective metasurfaces effectively showed different absorbing perform...

  6. Domain-Specific Ontology of Botany

    Institute of Scientific and Technical Information of China (English)

    Fang Gu; Cun-Gen Cao; Yue-Fei Sui; Wen Tian

    2004-01-01

    Domain-specific ontologies are greatly useful in knowledge acquisition, sharing and analysis. In this paper, botany-specific ontology for acquiring and analyzing botanical knowledge is presented. The ontology is represented in a set of well-defined categories, and each concept is viewed as an instance of certain category. The authors also introduce botany-specific axioms, an integral part of the ontology, for checking and reasoning with the acquired knowledge. Consistency, completeness and redundancy of the axioms are discussed.

  7. Moment Problems on Bounded and Unbounded Domains

    Directory of Open Access Journals (Sweden)

    Octav Olteanu

    2013-01-01

    Full Text Available Using approximation results, we characterize the existence of the solution for a two-dimensional moment problem in the first quadrant, in terms of quadratic forms, similar to the one-dimensional case. For the bounded domain case, one considers a space of complex analytic functions in a disk and a space of continuous functions on a compact interval. The latter result seems to give sufficient (and necessary conditions for the existence of a multiplicative solution.

  8. Associativity Between Feature Models Across Domains

    OpenAIRE

    Subramani, S; Gurumoorthy, B

    2003-01-01

    Associativity between feature models implies the automatic updating of different feature models of a part after changes are made in one of its feature models. This is an important requirement in a distributed and concurrent design environment, where integrity of part geometry has to be maintained through changes made in different task domains. The proposed algorithm takes multiple feature models of apart as input and modifies other feature models to reflect the changes made to a feature ...

  9. Domain decomposition methods for mortar finite elements

    Energy Technology Data Exchange (ETDEWEB)

    Widlund, O.

    1996-12-31

    In the last few years, domain decomposition methods, previously developed and tested for standard finite element methods and elliptic problems, have been extended and modified to work for mortar and other nonconforming finite element methods. A survey will be given of work carried out jointly with Yves Achdou, Mario Casarin, Maksymilian Dryja and Yvon Maday. Results on the p- and h-p-version finite elements will also be discussed.

  10. Single-domain antibodies for brain targeting

    OpenAIRE

    Lalatsa, Katerina; Moreira Leite, Diana

    2014-01-01

    Smaller recombinant antibody fragments as single-domain antibodies (sdAbs) are emerging as credible alternatives because of their target specificity, high affinity, and cost-effective recombinant production. sdAbs have been forged into multivalent and multispecif ic therapeutics, or targeting moieties, that are able to shuttle their linked therapeutic cargo (i.e., drugs, nanoparticles, toxins, enzymes, and radionuclides) to the receptor of interest. Their ability to permeate across the blood ...

  11. Singular integral on bounded strictly pseudoconvex domain

    Institute of Scientific and Technical Information of China (English)

    GONG Ding-dong

    2008-01-01

    Kytmanov and Myslivets gave a special Cauchy principal value of the singular integral on the bounded strictly pseudoconvex domain with smooth boundary. By means of this Cauchy integral principal value, the corresponding singular integral and a composition formula are obtained. This composition formula is quite different from usual ones in form. As an application, the corresponding singular integral equation and the system of singular integral equations are discussed as well.

  12. Domain of attraction in hybrid systems

    OpenAIRE

    Luk, Chuen-kit; 陸傳傑

    2015-01-01

    Domain of Attraction (DoA) is a set of initial conditions for which the system converges to the equilibrium point. In fact, it is a key problem in control engineering to guarantee stability within a workspace and avoid system failures. Classical applications include pendulum systems, tunnel diode circuits, mass-spring systems, negative-resistance oscillators and more recently, these have been found in other fields such as biology and ecology. This thesis firstly addresses the estimation o...

  13. Multiscale Medical Image Fusion in Wavelet Domain

    OpenAIRE

    Rajiv Singh; Ashish Khare

    2013-01-01

    Wavelet transforms have emerged as a powerful tool in image fusion. However, the study and analysis of medical image fusion is still a challenging area of research. Therefore, in this paper, we propose a multiscale fusion of multimodal medical images in wavelet domain. Fusion of medical images has been performed at multiple scales varying from minimum to maximum level using maximum selection rule which provides more flexibility and choice to select the relevant fused images. The experimental ...

  14. Two Probabilistic Powerdomains in Topological Domain Theory

    OpenAIRE

    Simpson, Alex; Battenfeld, Ingo

    2006-01-01

    We present two probabilistic powerdomain constructions in topological domain theory. The first is given by a free ”convex space” construction, fitting into the theory of modelling computational effects via free algebras for equational theories, as proposed by Plotkin and Power. The second is given by an observationally induced approach, following Schröder and Simpson. We show the two constructions coincide when restricted to ω-continuous dcppos, in which case they yield the space of (continuo...

  15. Circular domains nucleation in magnetic microwires

    Czech Academy of Sciences Publication Activity Database

    Chizhik, A.; Zablotskyy, Vitaliy A.; Stupakiewicz, A.; Dejneka, Alexandr; Polyakova, T.; Tekielak, M.; Maziewski, A.; Zhukov, A.; Gonzalez, J.

    2013-01-01

    Roč. 102, č. 20 (2013), "202406-1"-"202406-4". ISSN 0003-6951 R&D Projects: GA MŠk(CZ) LM2011029; GA TA ČR TA01010517; GA ČR GAP108/12/1941 Grant ostatní: SAFMAT(XE) CZ.2.16/3.1.00/22132 Institutional support: RVO:68378271 Keywords : magnetic microwires * magnetization reversal * domains nucleation Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 3.515, year: 2013

  16. On fictitious domain formulations for Maxwell's equations

    DEFF Research Database (Denmark)

    Dahmen, W.; Jensen, Torben Klint; Urban, K.

    2003-01-01

    We consider fictitious domain-Lagrange multiplier formulations for variational problems in the space H(curl: Omega) derived from Maxwell's equations. Boundary conditions and the divergence constraint are imposed weakly by using Lagrange multipliers. Both the time dependent and time harmonic formu...... formulations of the Maxwell's equations are considered. and we derive well-posed formulations for both cases. The variational problem that arises can be discretized by functions that do not satisfy an a-priori divergence constraint....

  17. Problem domain oriented approach for program comprehension

    OpenAIRE

    Pereira, Maria João; Berón, Mario; Cruz, Daniela; Oliveira, Nuno; Henriques, Pedro

    2012-01-01

    This paper is concerned with an ontology driven approach for Program Comprehension that starts picking up concepts from the problem domain ontology, analyzing source code and, after locating problem concepts in the code, goes up and links them to the programming language ontology. Different location techniques are used to search for concepts embedded in comments, in the code (identifier names and execution traces), and in string-literals associated with I/O statements. The expected res...

  18. Wittgensteinian Support for Domain Analysis in Classification

    OpenAIRE

    Wesolek, Andrew

    2012-01-01

    Hjorland contends that in order to further the goal of linking researchers to relevant information ‘domain analysis’ should be used in concept classification. He thinks that concept classification should not strive to classify on the basis of the properties of objects, but rather on descriptions of objects that are loosely derived from human activity and social negotiation. Currently, most information scientists operate under a ‘positivist’ view of concept classification, which, Hjorland main...

  19. Hidden supersymmetry of domain walls and cosmologies

    CERN Document Server

    Skenderis, K; Skenderis, Kostas; Townsend, Paul K.

    2006-01-01

    We show that all domain-wall solutions of gravity coupled to scalar fields for which the worldvolume geometry is Minkowski or anti-de Sitter admit Killing spinors, and satisfy corresponding first-order equations involving a superpotential determined by the solution. By analytic continuation, all flat or closed FLRW cosmologies are shown to satisfy similar first-order equations arising from the existence of ``pseudo-Killing'' spinors.

  20. Inviscid incompressible limits on expanding domains

    Czech Academy of Sciences Publication Activity Database

    Feireisl, Eduard; Nečasová, Šárka; Sun, Y.

    2014-01-01

    Roč. 27, č. 10 (2014), s. 2465-2477. ISSN 0951-7715 R&D Projects: GA ČR GA13-00522S Institutional support: RVO:67985840 Keywords : compressible Navier-Stokes system * large domain * inviscid limit * incompressible limit Subject RIV: BA - General Mathematics Impact factor: 1.208, year: 2014 http://iopscience.iop.org/0951-7715/27/10/2465/

  1. Time Domain Response of the ARIANNA Detector

    OpenAIRE

    Barwick, S. W.; Berg, E. C.; Besson, D. Z.; Hanson, J. C.; Klein, S. R.; Kleinfelder, S. A.; Piasecki, M.; Ratzlaff, K.; Reed, C.; Roumi, M.; Stezelberger, T.; Tatar, J.; Walker, J; Young, R.; Zou, L.

    2014-01-01

    The Antarctic Ross Ice Shelf Antenna Neutrino Array (ARIANNA) is a high-energy neutrino detector designed to record the Askaryan electric field signature of cosmogenic neutrino interactions in ice. To understand the inherent radio-frequency (RF) neutrino signature, the time-domain response of the ARIANNA RF receiver must be measured. ARIANNA uses Create CLP5130-2N log-periodic dipole arrays (LPDAs). The associated effective height operator converts incident electric fields to voltage waveform...

  2. Domain Walls Zoo in Supersymmetric QCD

    CERN Document Server

    Smilga, A V

    1998-01-01

    Solving numerically the equations of motion for the effective lagrangian describing supersymmetric QCD with the SU(2) gauge group, we find a menagerie of complex domain wall solutions connecting different chirally asymmetric vacua. Some of these solutions are BPS saturated walls; they exist when the mass of the matter fields does not exceed some critical value m m*, the complex walls disappear altogether and only the walls connecting a chirally asymmetric vacuum with the chirally symmetric one survive.

  3. Domain Walls Zoo in Supersymmetric QCD

    OpenAIRE

    Smilga, A. V.; Veselov, A. I.

    1997-01-01

    Solving numerically the equations of motion for the effective lagrangian describing supersymmetric QCD with the SU(2) gauge group, we find a menagerie of complex domain wall solutions connecting different chirally asymmetric vacua. Some of these solutions are BPS saturated walls; they exist when the mass of the matter fields does not exceed some critical value m < m* < 4.67059... There are also sphaleron branches (saddle points of the ebergy functional). In the range m* < m < m** \\approx 4.83...

  4. Gradient Domain Mesh Deformation - A Survey

    Institute of Scientific and Technical Information of China (English)

    Wei-Wei Xu; Kun Zhou

    2009-01-01

    This survey reviews the recent development of gradient domain mesh deformation method. Different to other deformation methods, the gradient domain deformation method is a surface-based, variational optimization method. It directly encodes the geometric details in differential coordinates, which are also called Laplacian coordinates in literature. By preserving the Laplacian coordinates, the mesh details can be well preserved during deformation. Due to the locality of the Laplacian coordinates, the variational optimization problem can be casted into a sparse linear system. Fast sparse linear solver can be adopted to generate deformation result interactively, or even in real-time. The nonlinear nature of gradient domain mesh deformation leads to the development of two categories of deformation methods: linearization methods and nonlinear optimization methods. Basically, the linearization methods only need to solve the linear least-squares system once. They are fast, easy to understand and control, while the deformation result might be suboptimal. Nonlinear optimization methods can reach optimal solution of deformation energy function by iterative updating. Since the computation of nonlinear methods is expensive, reduced deformable models should be adopted to achieve interactive performance. The nonlinear optimization methods avoid the user burden to input transformation at deformation handles, and they can be extended to incorporate various nonlinear constraints, like volume constraint, skeleton constraint, and so on. We review representative methods and related approaches of each category comparatively and hope to help the user understand the motivation behind the algorithms. Finally, we discuss the relation between physical simulation and gradient domain mesh deformation to reveal why it can achieve physically plausible deformation result.

  5. Image domain propeller fast spin echo☆

    Science.gov (United States)

    Skare, Stefan; Holdsworth, Samantha J.; Lilja, Anders; Bammer, Roland

    2013-01-01

    A new pulse sequence for high-resolution T2-weighted (T2-w) imaging is proposed –image domain propeller fast spin echo (iProp-FSE). Similar to the T2-w PROPELLER sequence, iProp-FSE acquires data in a segmented fashion, as blades that are acquired in multiple TRs. However, the iProp-FSE blades are formed in the image domain instead of in the k-space domain. Each iProp-FSE blade resembles a single-shot fast spin echo (SSFSE) sequence with a very narrow phase-encoding field of view (FOV), after which N rotated blade replicas yield the final full circular FOV. Our method of combining the image domain blade data to a full FOV image is detailed, and optimal choices of phase-encoding FOVs and receiver bandwidths were evaluated on phantom and volunteers. The results suggest that a phase FOV of 15–20%, a receiver bandwidth of ±32–63 kHz and a subsequent readout time of about 300 ms provide a good tradeoff between signal-to-noise ratio (SNR) efficiency and T2 blurring. Comparisons between iProp-FSE, Cartesian FSE and PROPELLER were made on single-slice axial brain data, showing similar T2-w tissue contrast and SNR with great anatomical conspicuity at similar scan times –without colored noise or streaks from motion. A new slice interleaving order is also proposed to improve the multislice capabilities of iProp-FSE. PMID:23200683

  6. Time-Dependent Dilatonic Domain Walls

    CERN Document Server

    La, H S

    1992-01-01

    Time-dependent domain wall solutions with infinitesimal thickness are obtained in the theory of a scalar field coupled to gravity with the dilaton, i.e. the Jordan-Brans-Dicke gravity. The value of the dilaton is determined in terms of the Brans-Dicke parameter $\\omega$. In particular, the solutions exist for any $\\omega>0$ and as $\\omega\\to\\infty$ we obtain new solutions in general relativity. They have horizons whose sizes depend on $\\omega$.

  7. Domain adaptation for Alzheimer's disease diagnostics.

    Science.gov (United States)

    Wachinger, Christian; Reuter, Martin

    2016-10-01

    With the increasing prevalence of Alzheimer's disease, research focuses on the early computer-aided diagnosis of dementia with the goal to understand the disease process, determine risk and preserving factors, and explore preventive therapies. By now, large amounts of data from multi-site studies have been made available for developing, training, and evaluating automated classifiers. Yet, their translation to the clinic remains challenging, in part due to their limited generalizability across different datasets. In this work, we describe a compact classification approach that mitigates overfitting by regularizing the multinomial regression with the mixed ℓ1/ℓ2 norm. We combine volume, thickness, and anatomical shape features from MRI scans to characterize neuroanatomy for the three-class classification of Alzheimer's disease, mild cognitive impairment and healthy controls. We demonstrate high classification accuracy via independent evaluation within the scope of the CADDementia challenge. We, furthermore, demonstrate that variations between source and target datasets can substantially influence classification accuracy. The main contribution of this work addresses this problem by proposing an approach for supervised domain adaptation based on instance weighting. Integration of this method into our classifier allows us to assess different strategies for domain adaptation. Our results demonstrate (i) that training on only the target training set yields better results than the naïve combination (union) of source and target training sets, and (ii) that domain adaptation with instance weighting yields the best classification results, especially if only a small training component of the target dataset is available. These insights imply that successful deployment of systems for computer-aided diagnostics to the clinic depends not only on accurate classifiers that avoid overfitting, but also on a dedicated domain adaptation strategy. PMID:27262241

  8. Helping Domain Experts Build Speech Translation Systems

    OpenAIRE

    Rayner, Manny; Armando, Alejandro; Bouillon, Pierrette; Ebling, Sarah; Gerlach, Johanna; Halimi, Sonia; Strasly, Irene; Tsourakis, Nikos

    2015-01-01

    We present a new platform, "Regulus Lite", which supports rapid development and web deployment of several types of phrasal speech translation systems using a minimal formalism. A distinguishing feature is that most development work can be performed directly by domain experts. We motivate the need for platforms of this type and discuss three specific cases: medical speech translation, speech-to-sign-language translation and voice questionnaires. We briefly describe initial experiences in devel...

  9. Interactions between domain walls and spin currents

    Science.gov (United States)

    Klaui, M.; Laufenberg, M.; Backes, D.; Buhrer, W.; Rudiger, U.; Vila, L.; Vouille, C.; Faini, G.

    2006-03-01

    A promising novel approach for switching magnetic nanostructures is current-induced domain wall propagation (CIDP), where due to a spin torque effect, electrons transfer angular momentum to a head-to-head domain wall and thereby push it in the direction of the electron flow without any externally applied fields. This effect has been observed with a variety of techniques including MFM [1] and spin polarized scanning electron microscopy [2] to directly observe current-induced domain wall propagation in ferromagnetic nanostructures and magnetoresistance measurements to systematically probe the critical current densities as a function of the geometry [3]. The observed wall velocities and critical current densities, where wall motion sets in at room temperature, do not agree well with theoretical 0K calculations [4]. We have therefore measured the critical current densities as a function of the sample temperature. We find that the spin torque effect becomes more efficient at low temperatures, which could account for some of the observed discrepancies between the 300K experiment and the 0K simulation. [1] A. Yamaguchi et al., Phys. Rev. Lett. 92, 77205 (2004); [2] M. Klaui et al., PRL 95, 26601 (2005); [3] M. Klaui et al., PRL 94, 106601 (2005); [4] A. Thiaville et al., EPL 69, 990 (2005); G. Tatara et al., APL 86, 252509 (2005);

  10. Evolution of a protein domain interaction network

    International Nuclear Information System (INIS)

    In this paper, we attempt to understand complex network evolution from the underlying evolutionary relationship between biological organisms. Firstly, we construct a Pfam domain interaction network for each of the 470 completely sequenced organisms, and therefore each organism is correlated with a specific Pfam domain interaction network; secondly, we infer the evolutionary relationship of these organisms with the nearest neighbour joining method; thirdly, we use the evolutionary relationship between organisms constructed in the second step as the evolutionary course of the Pfam domain interaction network constructed in the first step. This analysis of the evolutionary course shows: (i) there is a conserved sub-network structure in network evolution; in this sub-network, nodes with lower degree prefer to maintain their connectivity invariant, and hubs tend to maintain their role as a hub is attached preferentially to new added nodes; (ii) few nodes are conserved as hubs; most of the other nodes are conserved as one with very low degree; (iii) in the course of network evolution, new nodes are added to the network either individually in most cases or as clusters with relative high clustering coefficients in a very few cases. (general)

  11. Cloaking Effect of Superlens in Time Domain

    Science.gov (United States)

    Xiao, Meng; Dong, Jian Wen; Huang, Xueqin; Chan, Che Ting

    2012-02-01

    A ``perfect lens'' (ideal absorption-less slab with μ=?=-1) or ``superlens'' (a perfect lens with small absorption) can cloak a small object located in its vicinity such that no far field observer can detect the small particle, i.e., being invisible. While the problem is well understood in the steady state by solving the Maxwell equation in frequency domain, its time domain properties, such as how the cloaking effect started, remained unknown. In this paper, by using the time-dependent Green's function approach, we present a time domain study of the cloaking properties of the ``superlens'' As a current source is turned ``on,'' the system's response will be consisted of a transient response in the beginning and a steady state response in the long run. It turns out that it takes a long time (tens of thousands of cycle) for the ``perfect lens'' to build up the cloaking effect, and this required period depends on a number of factors, such as the separation between the lens and the particle, the absorption of the slab, and the dispersion of the slab. Moreover, along with many other interesting effects, we also find that, the dipole moment, on its way to be invisible, it oscillates with a decreasing amplitude.

  12. Time-Domain Filtering of Metasurfaces

    Science.gov (United States)

    Wakatsuchi, Hiroki

    2015-11-01

    In general electromagnetic response of each material to a continuous wave does not vary in time domain if the frequency component remains the same. Recently, it turned out that integrating several circuit elements including schottky diodes with periodically metallised surfaces, or the so-called metasurfaces, leads to selectively absorbing specific types of waveforms or pulse widths even at the same frequency. These waveform-selective metasurfaces effectively showed different absorbing performances for different widths of pulsed sine waves by gradually varying their electromagnetic responses in time domain. Here we study time-filtering effects of such circuit-based metasurfaces illuminated by continuous sine waves. Moreover, we introduce extra circuit elements to these structures to enhance the time-domain control capability. These time-varying properties are expected to give us another degree of freedom to control electromagnetic waves and thus contribute to developing new kinds of electromagnetic applications and technologies, e.g. time-windowing wireless communications and waveform conversion.

  13. BPS domain walls from backreacted orientifolds

    CERN Document Server

    Blåbäck, Johan; Van Riet, Thomas; Vercnocke, Bert

    2013-01-01

    Compactifications with D-brane and orientifold sources lead to standard gauged supergravity theories if the sources are smeared over the internal directions. It is therefore of interest to find how the solutions described by the gauged supergravity are altered by properly localising the sources. In this paper we analyse this for BPS domain wall solutions in the seven-dimensional gauged supergravity obtained from an O6 toroidal orientifold compactification in massive IIA supergravity. This is one of the simplest no-scale supergravities that can be constructed and analysed in full detail. We find and discuss the BPS domain walls both when the O6 planes are smeared and localised. When the O6 planes are localised the domain wall solutions live in a warped compactification. In order to get explicit expressions we also consider the non-compact versions of the solutions for which the O6 planes have been traded for D6 branes. Through T-duality we obtain partially localised solutions for compactifications to four dime...

  14. Metastable magnetic domain walls in cylindrical nanowires

    International Nuclear Information System (INIS)

    The stability of the asymmetric domain wall (ATDW) in soft magnetic cylindrical nanowires and nanotubes is investigated using micromagnetic simulations. Our calculated phase diagram shows that for cylindrical permalloy nanowires, the transverse domain wall (TDW) is the ground state for radii below 20 nm whilst the Bloch point wall (BPW) is favoured in thicker wires. The ATDW stabilises only as a metastable state but with energy close to that of the BPW. Characterisation of the DW spin structures reveals that the ATDW has a vortex-like surface spin state, in contrast to the divergent surface spins of the TDW. This results in lowering of surface charge above the critical radius. For both cylindrical nanotubes and nanowires we find that ATDWs only appear to exist as metastable static states and are particularly suppressed in nanotubes due to an increase in magnetostatic energy. - Highlights: • We simulate the micromagnetic structures of domain walls in cylindrical nanowires. • A phase diagram identifies ground and metastable states. • Asymmetric transverse walls are metastable in nanowires but suppressed in tubes. • Unrolling surface magnetisation aids visualisation of asymmetry and chirality. • We predict experimental discrimination based on magnetic charge distribution

  15. Domain specific software design for decision aiding

    Science.gov (United States)

    Keller, Kirby; Stanley, Kevin

    1992-01-01

    McDonnell Aircraft Company (MCAIR) is involved in many large multi-discipline design and development efforts of tactical aircraft. These involve a number of design disciplines that must be coordinated to produce an integrated design and a successful product. Our interpretation of a domain specific software design (DSSD) is that of a representation or framework that is specialized to support a limited problem domain. A DSSD is an abstract software design that is shaped by the problem characteristics. This parallels the theme of object-oriented analysis and design of letting the problem model directly drive the design. The DSSD concept extends the notion of software reusability to include representations or frameworks. It supports the entire software life cycle and specifically leads to improved prototyping capability, supports system integration, and promotes reuse of software designs and supporting frameworks. The example presented in this paper is the task network architecture or design which was developed for the MCAIR Pilot's Associate program. The task network concept supported both module development and system integration within the domain of operator decision aiding. It is presented as an instance where a software design exhibited many of the attributes associated with DSSD concept.

  16. Robust Image Watermarking in Frequency Domain

    Directory of Open Access Journals (Sweden)

    G. Dayalin Leena

    2013-04-01

    Full Text Available The spreading out of internet these days has raised the worth of digital media all over the planet. Digital watermarking has been a boon to digital media world as it endows various benefits like authentication, copy control and rights management of digital media. Digital images a category under digital media can be watermarked either in time domain or in frequency domain. The goal is to produce an efficient, secure and invisible watermarked image using digital watermarking thereby improving the quality and increasing the robustness of watermarked image. Here, digital image is watermarked using wavelet transforms which is an efficient multi-resolution frequency domain techniques. The low frequencies of wavelet decomposition of the carrier image which is a color image is watermarked with a color logo shuffled using a chaotic map technique. Embedding process is highly secured as chaotic map technique shuffles the watermark in order to confuse any unauthorized person who tries to modify or remove the corresponding watermark. The Peak Signal to Noise Ratio (PSNR of watermarked image has proved that the original image and the watermarked image are visually indistinguishable by human observers. Robustness is checked well by extracting the original watermark perfectly without any degradation in the original image.

  17. Bregmanized Domain Decomposition for Image Restoration

    KAUST Repository

    Langer, Andreas

    2012-05-22

    Computational problems of large-scale data are gaining attention recently due to better hardware and hence, higher dimensionality of images and data sets acquired in applications. In the last couple of years non-smooth minimization problems such as total variation minimization became increasingly important for the solution of these tasks. While being favorable due to the improved enhancement of images compared to smooth imaging approaches, non-smooth minimization problems typically scale badly with the dimension of the data. Hence, for large imaging problems solved by total variation minimization domain decomposition algorithms have been proposed, aiming to split one large problem into N > 1 smaller problems which can be solved on parallel CPUs. The N subproblems constitute constrained minimization problems, where the constraint enforces the support of the minimizer to be the respective subdomain. In this paper we discuss a fast computational algorithm to solve domain decomposition for total variation minimization. In particular, we accelerate the computation of the subproblems by nested Bregman iterations. We propose a Bregmanized Operator Splitting-Split Bregman (BOS-SB) algorithm, which enforces the restriction onto the respective subdomain by a Bregman iteration that is subsequently solved by a Split Bregman strategy. The computational performance of this new approach is discussed for its application to image inpainting and image deblurring. It turns out that the proposed new solution technique is up to three times faster than the iterative algorithm currently used in domain decomposition methods for total variation minimization. © Springer Science+Business Media, LLC 2012.

  18. Unmanned Aerial Vehicle Domain: Areas of Research

    Directory of Open Access Journals (Sweden)

    Kadir Alpaslan Demir

    2015-07-01

    Full Text Available Unmanned aerial vehicles (UAVs domain has seen rapid developments in recent years. As the number of UAVs increases and as the missions involving UAVs vary, new research issues surface. An overview of the existing research areas in the UAV domain has been presented including the nature of the work categorised under different groups. These research areas are divided into two main streams: Technological and operational research areas. The research areas in technology are divided into onboard and ground technologies. The research areas in operations are divided into organization level, brigade level, user level, standards and certifications, regulations and legal, moral, and ethical issues. This overview is intended to serve as a starting point for fellow researchers new to the domain, to help researchers in positioning their research, identifying related research areas, and focusing on the right issues.Defence Science Journal, Vol. 65, No. 4, July 2015, pp. 319-329, DOI: http://dx.doi.org/10.14429/dsj.65.8631

  19. Birdsong dialect patterns explained using magnetic domains

    Science.gov (United States)

    Burridge, James; Kenney, Steven

    2016-06-01

    The songs and calls of many bird species, like human speech, form distinct regional dialects. We suggest that the process of dialect formation is analogous to the physical process of magnetic domain formation. We take the coastal breeding grounds of the Puget Sound white crowned sparrow as an example. Previous field studies suggest that birds of this species learn multiple songs early in life, and when establishing a territory for the first time, retain one of these dialects in order to match the majority of their neighbors. We introduce a simple lattice model of the process, showing that this matching behavior can produce single dialect domains provided the death rate of adult birds is sufficiently low. We relate death rate to thermodynamic temperature in magnetic materials, and calculate the critical death rate by analogy with the Ising model. Using parameters consistent with the known behavior of these birds we show that coastal dialect domain shapes may be explained by viewing them as low-temperature "stripe states."

  20. PREFACE: Domain wall dynamics in nanostructures Domain wall dynamics in nanostructures

    Science.gov (United States)

    Marrows, C. H.; Meier, G.

    2012-01-01

    Domain structures in magnetic materials are ubiquitous and have been studied for decades. The walls that separate them are topological defects in the magnetic order parameter and have a wide variety of complex forms. In general, their investigation is difficult in bulk materials since only the domain structure on the surface of a specimen is visible. Cutting the sample to reveal the interior causes a rearrangement of the domains into a new form. As with many other areas of magnetism, the study of domain wall physics has been revitalised by the advent of nanotechnology. The ability to fabricate nanoscale structures has permitted the formation of simplified and controlled domain patterns; the development of advanced microscopy methods has permitted them to be imaged and then modelled; subjecting them to ultrashort field and current pulses has permitted their dynamics to be explored. The latest results from all of these advances are described in this special issue. Not only has this led to results of great scientific beauty, but also to concepts of great applicability to future information technologies. In this issue the reader will find the latest results for these domain wall dynamics and the high-speed processes of topological structures such as domain walls and magnetic vortices. These dynamics can be driven by the application of magnetic fields, or by flowing currents through spintronic devices using the novel physics of spin-transfer torque. This complexity has been studied using a wide variety of experimental techniques at the edge of the spatial and temporal resolution currently available, and can be described using sophisticated analytical theory and computational modelling. As a result, the dynamics can be engineered to give rise to finely controlled memory and logic devices with new functionality. Moreover, the field is moving to study not only the conventional transition metal ferromagnets, but also complex heterostructures, novel magnets and even other

  1. Tunable conductance of magnetic nanowires with structured domain walls.

    Science.gov (United States)

    Dugaev, V K; Berakdar, J; Barnaś, J

    2006-02-01

    We show that in a magnetic nanowire with double magnetic domain walls, quantum interference results in spin-split quasistationary states localized mainly between the domain walls. Spin-flip-assisted transmission through the domain structure increases strongly when these size-quantized states are tuned on resonance with the Fermi energy, e.g., upon varying the distance between the domain walls which results in resonance-type peaks of the wire conductance. This novel phenomenon is shown to be utilizable to manipulate the spin density in the domain vicinity. The domain wall parameters are readily controllable, and the predicted effect is hence exploitable in spintronic devices. PMID:16486888

  2. Lipid Bilayer Domain Fluctuations as a Probe of Membrane Viscosity

    Science.gov (United States)

    Camley, Brian A.; Esposito, Cinzia; Baumgart, Tobias; Brown, Frank L.H.

    2010-01-01

    We argue that membrane viscosity, ηm, plays a prominent role in the thermal fluctuation dynamics of micron-scale lipid domains. A theoretical expression is presented for the timescales of domain shape relaxation, which reduces to the well-known ηm = 0 result of Stone and McConnell in the limit of large domain sizes. Experimental measurements of domain dynamics on the surface of ternary phospholipid and cholesterol vesicles confirm the theoretical results and suggest domain flicker spectroscopy as a convenient means to simultaneously measure both the line tension, σ, and the membrane viscosity, ηm, governing the behavior of individual lipid domains. PMID:20858410

  3. Structure-dependent electrical conductivity of protein: its differences between alpha-domain and beta-domain structures.

    Science.gov (United States)

    Zhang, X Y; Shao, Jian; Jiang, S X; Wang, Biao; Zheng, Yue

    2015-03-27

    Electron transports in the α-domain and β-domain of proteins have been comprehensively investigated. The structure-dependent electron transport of proteins has been experimentally measured and theoretically simulated, and both the theoretical and experimental results demonstrate significant differences in electrical conductivity between the α-domain and β-domain. By controlling the feedback system of the scanning tunneling microscope (STM), the conductance of a single α-domain protein hemoglobin (Hgb) and a β-domain protein superoxide dismutase enzyme (SOD) were measured, respectively. The current signal of Hgb is obviously stronger, indicating that the α-domain is more conductive. To confirm our finding, molecular orbitals of both the β-domain in SOD and α-domain in Hgb have been analyzed based on first-principles calculations. As expected, tunneling transport and hopping in the α-domain are both more efficient, indicating that it is easier for electrons to transport through the α-domain, which are in great agreement with our experimental data. In order to explain our results, molecular structures of α- and β-domains have been carefully analyzed and show that the explanation should lie in the differences in packing mode between the α-domain and β-domain. This research should be very important to application prospects in molecular electronics. PMID:25736549

  4. Structure-dependent electrical conductivity of protein: its differences between alpha-domain and beta-domain structures

    International Nuclear Information System (INIS)

    Electron transports in the α-domain and β-domain of proteins have been comprehensively investigated. The structure-dependent electron transport of proteins has been experimentally measured and theoretically simulated, and both the theoretical and experimental results demonstrate significant differences in electrical conductivity between the α-domain and β-domain. By controlling the feedback system of the scanning tunneling microscope (STM), the conductance of a single α-domain protein hemoglobin (Hgb) and a β-domain protein superoxide dismutase enzyme (SOD) were measured, respectively. The current signal of Hgb is obviously stronger, indicating that the α-domain is more conductive. To confirm our finding, molecular orbitals of both the β-domain in SOD and α-domain in Hgb have been analyzed based on first-principles calculations. As expected, tunneling transport and hopping in the α-domain are both more efficient, indicating that it is easier for electrons to transport through the α-domain, which are in great agreement with our experimental data. In order to explain our results, molecular structures of α- and β-domains have been carefully analyzed and show that the explanation should lie in the differences in packing mode between the α-domain and β-domain. This research should be very important to application prospects in molecular electronics. (paper)

  5. Thermomagnetic Stability in Pseudo Single Domain Grains

    Science.gov (United States)

    Nagy, Lesleis; Williams, Wyn; Muxworthy, Adrian; Fabian, Karl; Conbhuí, Pádraig Ó.

    2016-04-01

    The reliability of paleomagnetic remanences are well understood for fine grains of magnetite that are single-domain (SD, uniformly magnetized). In particular Néel's theory [1] outlined the thermal energies required to block and unblock magnetic remanences. This lead to determination of thermal stability for magnetization in fine grains as outlined in Pullaiah et. al. [2] and a comprehensive understanding of SD paleomagnetic recordings. It has been known for some time that single domain magnetite is possible only in the grain size range 30 - 80nm, which may only account for a small fraction of the grain size distribution in any rock sample. Indeed rocks are often dominated by grains in the pseudo single domain (PSD) size range, at approximately 80 - 1000nm. Toward the top end of this range multi-domain features begin to dominate. In order to determine thermomagnetic stability in PSD grains we need to identify the energy barriers between all possible pairs of local energy minima (LEM) domain states as a function of both temperature and grain size. We have attempted to do this using the nudged elastic band (NEB) method [3] which searches for minimum energy paths between any given pair of LEM states. Using this technique we have determined, for the first time, complete thermomagnetic stability curves for PSD magnetite. The work presented is at a preliminary stage. However it can be shown that PSD grains of magnetite with simple geometries (e.g. cubes or cuboctahedra) have very few low energy transition paths and the stability is likely to be similar to that observed for SD grains (as expected form experimental observations). The results will provide a basis for a much more rigorous understanding of the fidelity of paleomagnetic signals in assemblages of PSD grains and their ability to retain ancient recordings of the geomagnetic field. References: [1] Néel, Louis. "Théorie du traînage magnétique des ferromagnétiques en grains fins avec applications aux terres

  6. Unusual domain evolution in semiconducting ferroelectrics: A phase field study

    International Nuclear Information System (INIS)

    The effect of electrical conductivity on the domain evolution of semiconducting ferroelectrics is investigated using a phase field model which includes the drift of space charges. Phase field simulations show that the tail-to-tail 90° charged domain wall appears during the domain formation in the semiconducting ferroelectrics at zero field, which is prohibited in common insulating ferroelectrics. Due to the screening of polarization charges, the domain switching takes place through the motion of head-to-head 180° charged domain wall in the semiconducting single-domain ferroelectrics subjected to an electric field. Comparing to the insulating ferroelectrics, the semiconducting ferroelectrics have a lower speed of domain evolution due to the decrease of mobility of charged domain walls. The response of semiconducting ferroelectrics to a mechanical load is also found different from that of insulating ferroelectrics. - Highlights: • Phase field simulations reveal an unusual domain evolution with charged domain wall in the semiconducting ferroelectrics. • The semiconducting ferroelectrics have a lower speed of domain evolution than the insulating ones. • The thickness of charged domain wall is found larger than that of neutral wall, which is consistent with the experimental observation. • The evolution of charged domain wall gives an insight into the current leakage in ferroelectric devices

  7. Protein complex prediction via verifying and reconstructing the topology of domain-domain interactions

    Directory of Open Access Journals (Sweden)

    Kashima Hisashi

    2010-06-01

    Full Text Available Abstract Background High-throughput methods for detecting protein-protein interactions enable us to obtain large interaction networks, and also allow us to computationally identify the associations of proteins as protein complexes. Although there are methods to extract protein complexes as sets of proteins from interaction networks, the extracted complexes may include false positives because they do not account for the structural limitations of the proteins and thus do not check that the proteins in the extracted complex can simultaneously bind to each other. In addition, there have been few searches for deeper insights into the protein complexes, such as of the topology of the protein-protein interactions or into the domain-domain interactions that mediate the protein interactions. Results Here, we introduce a combinatorial approach for prediction of protein complexes focusing not only on determining member proteins in complexes but also on the DDI/PPI organization of the complexes. Our method analyzes complex candidates predicted by the existing methods. It searches for optimal combinations of domain-domain interactions in the candidates based on an assumption that the proteins in a candidate can form a true protein complex if each of the domains is used by a single protein interaction. This optimization problem was mathematically formulated and solved using binary integer linear programming. By using publicly available sets of yeast protein-protein interactions and domain-domain interactions, we succeeded in extracting protein complex candidates with an accuracy that is twice the average accuracy of the existing methods, MCL, MCODE, or clustering coefficient. Although the configuring parameters for each algorithm resulted in slightly improved precisions, our method always showed better precision for most values of the parameters. Conclusions Our combinatorial approach can provide better accuracy for prediction of protein complexes and also

  8. IMGT unique numbering for immunoglobulin and T cell receptor constant domains and Ig superfamily C-like domains

    DEFF Research Database (Denmark)

    Lefranc, Marie-Paule; Pommié, Christelle; Kaas, Quentin;

    2005-01-01

    the C-LIKE-DOMAINs, leading, for the first time, to their standardized description of mutations, allelic polymorphisms, two-dimensional (2D) representations and tridimensional (3D) structures. The IMGT unique numbering is, therefore, highly valuable for the comparative, structural or evolutionary...... immune system (RPI) of human and other vertebrates. The NUMEROTATION concept of IMGT-ONTOLOGY has allowed to define a unique numbering for the variable domains (V-DOMAINs) and for the V-LIKE-DOMAINs. In this paper, this standardized characterization is extended to the constant domains (C-DOMAINs), and to...

  9. On Some Properties of Squeezing Functions of Bounded Domains

    CERN Document Server

    Deng, Fusheng; Zhang, Liyou

    2011-01-01

    The main purpose of the present paper is to introduce the notion of squeezing functions of bounded domains and study some properties of them. The relation to geometric and analytic structures of bounded domains will be investigated. Existence of related extremal maps and continuity of squeezing functions are proved. Holomorphic homogeneous regular domains are exactly domains whose squeezing functions have positive lower bounds. Completeness of certain intrinsic metrics and pseudoconvexity of holomorphic homogeneous regular domains are proved by alternative method. In dimension one case, we get a neat description of boundary behavior of squeezing functions of finitely connected planar domains. This leads to a necessary and sufficient conditions for a finitely connected planar domain to be a holomorphic homogeneous regular domain. Consequently, we can recover some important results in complex analysis. For annuli, we obtain some interesting properties of their squeezing functions. We finally exhibit some exampl...

  10. Periodic magnetic domains in single-crystalline cobalt filament arrays

    Science.gov (United States)

    Chen, Fei; Wang, Fan; Jia, Fei; Li, Jingning; Liu, Kai; Huang, Sunxiang; Luan, Zhongzhi; Wu, Di; Chen, Yanbin; Zhu, Jianmin; Peng, Ru-Wen; Wang, Mu

    2016-02-01

    Magnetic structures with controlled domain wall pattern may be applied as potential building blocks for three-dimensional magnetic memory and logic devices. Using a unique electrochemical self-assembly method, we achieve regular single-crystalline cobalt filament arrays with specific geometric profile and crystallographic orientation, and the magnetic domain configuration can be conveniently tailored. We report the transition of periodic antiparallel magnetic domains to compressed vortex magnetic domains depending on the ratio of height to width of the wires. A "phase diagram" is obtained to describe the dependence of the type of magnetic domain and the geometrical profiles of the wires. Magnetoresistance of the filaments demonstrates that the contribution of a series of 180∘ domain walls is over 0.15 % of the zero-field resistance ρ (H =0 ) . These self-assembled magnetic nanofilaments, with controlled periodic domain patterns, offer an interesting platform to explore domain-wall-based memory and logic devices.

  11. Domain structure of black hole space-times

    International Nuclear Information System (INIS)

    We introduce the domain structure for stationary black hole space-times. The domain structure lives on the submanifold of fixed points of the Killing vector fields. Depending on which Killing vector field has fixed points the submanifold is naturally divided into domains. The domain structure provides invariants of the space-time, both topological and continuous. It is defined for any space-time dimension and any number of Killing vector fields. We examine the domain structure for asymptotically flat space-times and find a canonical form for the metric of such space-times. The domain structure generalizes the rod structure introduced for space-times with D-2 commuting Killing vector fields. We analyze in detail the domain structure for Minkowski space, the Schwarzschild-Tangherlini black hole and the Myers-Perry black hole in six and seven dimensions. Finally, we consider the possible domain structures for asymptotically flat black holes in six and seven dimensions.

  12. Effects of sub-domain structure on initial magnetization curve and domain size distribution of stacked media

    International Nuclear Information System (INIS)

    In this paper, in order to confirm the sub-domain structure in stacked media demagnetized with in-plane field, initial magnetization curves and magnetic domain size distribution were investigated. Both experimental and simulation results showed that an initial magnetization curve for the medium demagnetized with in-plane field (MDI) initially rose faster than that for the medium demagnetized with perpendicular field (MDP). It is inferred that this is because the MDI has a larger number of domain walls than the MDP due to the existence of the sub-domains, resulting in an increase in the probability of domain wall motion. Dispersion of domain size for the MDI was larger than that for the MDP. This is because sub-domains are formed not only inside the domain but also at the domain boundary region, and they change the position of the domain boundary to affect the domain size. - Highlights: • An initial magnetization curve for MDI initially rose faster than that for MDP. • Dispersion of domain size for the MDI was larger than that for the MDP. • Experimental and simulation results can be explained by existence of sub-domains

  13. Entropy production by domain wall decay in the NMSSM

    CERN Document Server

    Hattori, Hironori; Omoto, Naoya; Seto, Osamu

    2015-01-01

    We consider domain walls in the $Z_3$ symmetric NMSSM. The spontaneous $Z_3$ discrete symmetry breaking produces domain walls, and the stable domain walls are problematic. Thus, we assume the $Z_3$ symmetry is slightly but explicitly broken and the domain walls decay. Such a decay causes a large late-time entropy production. We study its cosmological implications on unwanted relics such as moduli, gravitino, LSP and axion.

  14. Combining statistical machine translation and translation memories with domain adaptation

    OpenAIRE

    Läubli, Samuel; Fishel, Mark; Volk, Martin; Weibel, Manuela

    2013-01-01

    Since the emergence of translation memory software, translation companies and freelance translators have been accumulating translated text for various languages and domains. This data has the potential of being used for training domain-specific machine translation systems for corporate or even personal use. But while the resulting systems usually perform well in translating domain-specific language, their out-of-domain vocabulary coverage is often insufficient due to the limited size of the t...

  15. Tunable conductance of magnetic nanowires with structured domain walls

    OpenAIRE

    Dugaev, V. K.; Berakdar, J.; Barnas, J.

    2006-01-01

    We show that in a magnetic nanowire with double magnetic domain walls, quantum interference results in spin-split quasistationary states localized mainly between the domain walls. Spin-flip-assisted transmission through the domain structure increases strongly when these size-quantized states are tuned on resonance with the Fermi energy, e.g. upon varying the distance between the domain walls which results in resonance-type peaks of the wire conductance. This novel phenomena is shown to be uti...

  16. Reuse of structural domain–domain interactions in protein networks

    OpenAIRE

    Bateman Alex; Schuster-Böckler Benjamin

    2007-01-01

    Abstract Background Protein interactions are thought to be largely mediated by interactions between structural domains. Databases such as iPfam relate interactions in protein structures to known domain families. Here, we investigate how the domain interactions from the iPfam database are distributed in protein interactions taken from the HPRD, MPact, BioGRID, DIP and IntAct databases. Results We find that known structural domain interactions can only explain a subset of 4–19% of the available...

  17. Pumilio Puf domain RNA-binding proteins in Arabidopsis

    OpenAIRE

    Abbasi, Nazia; Park, Youn-Il; Choi, Sang-Bong

    2011-01-01

    Pumilio proteins are a class of RNA-binding proteins harboring Puf domains (or PUM-HD; Pumilio-Homology Domain), named after the founding members, Pumilio (from Drosophila melanogaster) and FBF (Fem-3 mRNA-Binding Factor from Caenorhabditis elegans). The domains contain multiple tandem repeats each of which recognizes one RNA base and is comprised of 35–39 amino acids. Puf domain proteins have been reported in organisms ranging from single-celled yeast to higher multicellular eukaryotes, such...

  18. Hamilton-Jacobi method for Domain Walls and Cosmologies

    OpenAIRE

    Skenderis, Kostas; Townsend, Paul K.

    2006-01-01

    We use Hamiltonian methods to study curved domain walls and cosmologies. This leads naturally to first order equations for all domain walls and cosmologies foliated by slices of maximal symmetry. For Minkowski and AdS-sliced domain walls (flat and closed FLRW cosmologies) we recover a recent result concerning their (pseudo)supersymmetry. We show how domain-wall stability is consistent with the instability of adS vacua that violate the Breitenlohner-Freedman bound. We also explore the relation...

  19. Domain Generalization for Object Recognition with Multi-task Autoencoders

    OpenAIRE

    Ghifary, Muhammad; Kleijn, W. Bastiaan; Zhang, Mengjie; Balduzzi, David

    2015-01-01

    The problem of domain generalization is to take knowledge acquired from a number of related domains where training data is available, and to then successfully apply it to previously unseen domains. We propose a new feature learning algorithm, Multi-Task Autoencoder (MTAE), that provides good generalization performance for cross-domain object recognition. Our algorithm extends the standard denoising autoencoder framework by substituting artificially induced corruption with naturally occurring ...

  20. Non-manipulable domains for the Borda count

    OpenAIRE

    Barbie, Martin; Puppe, Clemens; Tasnádi, Attila

    2006-01-01

    We characterize the preference domains on which the Borda count satisfies Arrow's ``independence of irrelevant alternatives" condition. Under a weak richness condition, these domains are obtained by fixing one preference ordering and including all its cyclic permutations (``Condorcet cycles"). We then ask on which domains the Borda count is non-manipulable. It turns out that it is non-manipulable on a broader class of domains when combined with appropriately chosen tie-breaking rules. On the ...

  1. Domain Knowledge Management in Information-providing Dialogue Systems

    OpenAIRE

    Flycht-Eriksson (Silvervarg), Annika

    2001-01-01

    In this thesis a new concept called domain knowledge management for informationproviding dialogue systems is introduced. Domain knowledge management includes issues related to representation and use of domain knowledge as well as access of background information sources, issues that previously have been incorporated in dialogue management. The work on domain knowledge management reported in this thesis can be divided in two parts. On a general theoretical level, knowledge sources and models u...

  2. Credentialing Data Scientists: A Domain Repository Perspective

    Science.gov (United States)

    Lehnert, K. A.; Furukawa, H.

    2015-12-01

    A career in data science can have many paths: data curation, data analysis, metadata modeling - all of these in different commercial or scientific applications. Can a certification as 'data scientist' provide the guarantee that an applicant or candidate for a data science position has just the right skills? How valuable is a 'generic' certification as data scientist for an employer looking to fill a data science position? Credentials that are more specific and discipline-oriented may be more valuable to both the employer and the job candidate. One employment sector for data scientists are the data repositories that provide discipline-specific data services for science communities. Data science positions within domain repositories include a wide range of responsibilities in support of the full data life cycle - from data preservation and curation to development of data models, ontologies, and user interfaces, to development of data analysis and visualization tools to community education and outreach, and require a substantial degree of discipline-specific knowledge of scientific data acquisition and analysis workflows, data quality measures, and data cultures. Can there be certification programs for domain-specific data scientists that help build the urgently needed workforce for the repositories? The American Geophysical Union has recently started an initiative to develop a program for data science continuing education and data science professional certification for the Earth and space sciences. An Editorial Board has been charged to identify and develop curricula and content for these programs and to provide input and feedback in the implementation of the program. This presentation will report on the progress of this initiative and evaluate its utility for the needs of domain repositories in the Earth and space sciences.

  3. Compassion and professional care: exploring the domain.

    Science.gov (United States)

    van der Cingel, Margreet

    2009-04-01

    Compassion unites people during times of suffering and distress. Unfortunately, compassion cannot take away suffering. Why then, is compassion important for people who suffer? Nurses work in a domain where human suffering is evidently present. In order to give meaning to compassion in the domain of professional care, it is necessary to describe what compassion is. The purpose of this paper is to explore questions and contradictions in the debate on compassion related to nursing care. The paper reviews classical philosophers as well as contemporary scientists' main arguments on compassion. First, I will examine the relationship between compassion and suffering. Second, how does one recognize serious suffering? This issue raises questions about the role of imagination and the need for identification. Third, literature describes compassion as an emotion. Some philosophers consider emotions uncontrollable feelings; others see a clear rational dimension in emotions. In order to determine what compassion is, it is necessary to weigh these contradictional arguments. Fourth, I will discuss motives for compassion. Is compassion an act of altruism or egoism? In this debate Nietzsche and Schopenhauer are well-known opponents. Today, analysis of their arguments leads to some surprising conclusions. Fifth, there is the issue of fault and compassion. Can we only feel compassionate when people who suffer are not to blame for their own suffering? Such a condition faces professional caretakers with a dilemma which needs a thorough analysis if compassion is to be of use in the field of professional care. Finally, I will explore the moral meaning of compassion. Compassion, described as a concept with cognitive as well as affective dimensions, also has volitional and behavioural aspects. These aspects specifically are of importance to nursing care and further research of compassion in the nursing domain. PMID:19291200

  4. Recognition specificity of individual EH domains of mammals and yeast

    DEFF Research Database (Denmark)

    Paoluzi, S; Castagnoli, L; Lauro, I; Salcini, A E; Coda, L; Fre', S; Confalonieri, S; Pelicci, P G; Di Fiore, P P; Cesareni, G

    1998-01-01

    by characterizing the peptide-binding preference of 11 different EH domains from mammal and yeast proteins. Ten of the eleven EH domains could bind at least some peptides containing an Asn-Pro-Phe (NPF) motif. By contrast, the first EH domain of End3p preferentially binds peptides containing an His...

  5. Conception of Learning Outcomes in the Bloom's Taxonomy Affective Domain

    Science.gov (United States)

    Savickiene, Izabela

    2010-01-01

    The article raises a problematic issue regarding an insufficient base of the conception of learning outcomes in the Bloom's taxonomy affective domain. The search for solutions introduces the conception of teaching and learning in the affective domain as well as presents validity criteria of learning outcomes in the affective domain. The…

  6. K-groups of Toeplitz algebras on connected domains

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In the present paper, it is proved that the K0-group of a Toeplitz algebra on any connected domain is always isomorphic to the K0-group of the relative continuous function algebra. In addition, the cohomotopy groups of essential boundaries of some connected domains are computed, and the K0-groups of the continuous function algebras on these domains are also computed.

  7. Second-harmonic imaging of ferroelectric domain walls

    DEFF Research Database (Denmark)

    Bozhevolnyi, Sergey I.; Hvam, Jørn Märcher; Pedersen, Kjeld; Laurell, Fredrik; Karlsson, Håkan; Skettrup, Torben; Belmonte, Michele

    1998-01-01

    Domain walls in periodically poled ferroelectric KTiOPO4 and LiNbO3 crystals are observed by making use of second-harmonic (SH) generation enhancement in the transition regions between neighboring domains. SH images of domain walls obtained with various samples for different polarization configur...

  8. Between- and Within-Domain Relations of Students' Academic Emotions

    Science.gov (United States)

    Goetz, Thomas; Frenzel, Anne C.; Pekrun, Reinhard; Hall, Nathan C.; Ludtke, Oliver

    2007-01-01

    The authors investigated between- and within-domain relations of academic emotions, including students' enjoyment, pride, anxiety, anger, and boredom experienced in mathematics, physics, German, and English classes (N = 542; Grades 8 and 11). Corroborating assumptions of domain specificity, the between-domains relations of these emotions were weak…

  9. On frequency and time domain models of traveling wave tubes

    CERN Document Server

    Théveny, Stéphane; Elskens, Yves

    2016-01-01

    We discuss the envelope modulation assumption of frequency-domain models of traveling wave tubes (TWTs) and test its consistency with the Maxwell equations. We compare the predictions of usual frequency-domain models with those of a new time domain model of the TWT.

  10. A generalised finite domain constraint solver for SWI-Prolog

    NARCIS (Netherlands)

    M. Triska; U. Neumerkel; J. Wielemaker

    2008-01-01

    In this paper we describe a new constraint solver over finite domains that has recently been included in the SWI-Prolog distribution 1. Our solver generalises finite domain constraint solving towards unbounded domains, and thus enables a uniform approach to integer arithmetic and constraints. We ens

  11. A global reference model of the domain name system

    NARCIS (Netherlands)

    Koc, Y.; Jamakovic, A.; Gijsen, B.M.M.

    2012-01-01

    The domain name system (DNS) is a crucial component of the Internet. At this time, the DNS is facing major changes such as the introduction of DNSSEC and Internationalized Domain Name extensions (IDNs), the adoption of IPv6 and the upcoming extension of new generic top-level domains. These changes c

  12. Domain-specific knowledge as playful interaction

    DEFF Research Database (Denmark)

    Valente, Andrea; Marchetti, Emanuela

    2015-01-01

    the design process of Prime Slaughter, to move further in developing a general approach in developing games, aimed at effectively conveying knowledge from a specific domain. Hence this paper will discuss the past design process, as a concrete case, and then formulate a theoretical framework, based on......Starting from reflections on designing games for learning, aimed at providing a tangible grounding to abstract knowledge, we designed Prime Slaughter, a game to support learning of factorisation and prime numbers, targeted to primary and early secondary school children. This new study draws upon...

  13. Transposition of Domain Knowledge into Educational Games

    DEFF Research Database (Denmark)

    Marchetti, Emanuela; Jensen, Kristoffer; Valente, Andrea

    2014-01-01

    interactions, through the design of interactive media. PlayDT aims at facilitating the creation of a creative and easy understandable mapping between knowledge and interaction within the game. Multiple representations are encouraged, so to allow learners to express their own preferences, regarding their play...... mapping, we designed PrimeSlaughter, a computer game aimed at supporting learning of prime numbers and factorization, for later primary and early secondary school pupils; the same domain concepts were mapped into two play styles in the game. In this study, we intend to go further in our formulation of the...

  14. Solitons for optical time-domain reflectometry

    Science.gov (United States)

    Levanon, Amikam; Friberg, Stephen R.; Fujii, Yoichi

    1996-06-01

    We describe the propagation of solitons in an optical time-domain reflectometry geometry. Intense nonsolitons usually broaden nonlinearly as they propagate out to a scatterer and broaden linearly as they return to their origin. In contrast, solitons propagate with a fixed pulse width or narrow on their way out to the scatterer. Returning, they broaden or narrow depending on their chirp at the scattering point. For a fixed return-pulse timing resolution we find 2.6 times or more energy can be launched when solitons are used than for normal dispersion pulses.

  15. Bosonic interactions with a domain wall

    CERN Document Server

    Morris, J R

    2016-01-01

    We consider here the interaction of scalar bosons with a topological domain wall. Not only is there a continuum of scattering states, but there is also an interesting "quasi-discretuum" of positive energy bosonic bound states, describing bosons entrapped within the wall's core. The full spectrum of the scattering and bound state energies and eigenstates is obtainable from a Schr\\"odinger-type of equation with a P\\"oschl-Teller potential. We also consider the presence of a boson gas within the wall and high energy boson emission.

  16. PARTITION PROPERTY OF DOMAIN DECOMPOSITION WITHOUT ELLIPTICITY

    Institute of Scientific and Technical Information of China (English)

    Mo Mu; Yun-qing Huang

    2001-01-01

    Partition property plays a central role in domain decomposition methods. Existing theory essentially assumes certain ellipticity. We prove the partition property for problems without ellipticity which are of practical importance. Example applications include implicit schemes applied to degenerate parabolic partial differential equations arising from superconductors, superfluids and liquid crystals. With this partition property, Schwarz algorithms can be applied to general non-elliptic problems with an h-independent optimal convergence rate. Application to the time-dependent Ginzburg-Landau model of superconductivity is illustrated and numerical results are presented.

  17. Jackson's Theorem on Bounded Symmetric Domains

    Institute of Scientific and Technical Information of China (English)

    Ming Zhi WANG; Guang Bin REN

    2007-01-01

    Polynomial approximation is studied on bounded symmetric domain Ω in C n for holo-morphic function spaces X ,such as Bloch-type spaces,Bergman-type spaces,Hardy spaces,Ω algebra and Lipschitz space.We extend the classical Jackson ’s theorem to several complex variables:E k f,X ) ω (1 /k,f,X ),where E k f,X )is the deviation of the best approximation of f ∈X by polynomials of degree at mostk with respect to the X -metric and ω (1/k,f,X )is the corresponding modulus of continuity.

  18. Software processes: how important is your domain?

    OpenAIRE

    Richardson, Ita

    2014-01-01

    peer-reviewed There was a time when researching software processes meant just that – we were interested in making sure that the process for software development was effective. We did not really have to worry about the domains in which our software was used – well, maybe that was up to the requirements engineers or even those who were interested in usability, but it did not really affect the software processes through which the software was developed. But, things have changed! Software h...

  19. Time-domain multiple-quantum NMR

    International Nuclear Information System (INIS)

    The development of time-domain multiple-quantum nuclear magnetic resonance is reviewed through mid 1982 and some prospects for future development are indicated. Particular attention is given to the problem of obtaining resolved, interpretable, many-quantum spectra for anisotropic magnetically isolated systems of coupled spins. New results are presented on a number of topics including the optimization of multiple-quantum-line intensities, analysis of noise in two-dimensional spectroscopy, and the use of order-selective excitation for cross polarization between nuclear-spin species

  20. Magnetic Domain Confinement by Anisotropy Modulation

    Science.gov (United States)

    Li, S. P.; Lew, W. S.; Bland, J. A.; Lopez-Diaz, L.; Vaz, C. A.; Natali, M.; Chen, Y.

    2002-02-01

    The spin configuration in a magnet is in general a ``natural'' consequence of both the intrinsic properties of the material and the sample dimensions. We demonstrate that this limitation can be overcome in a homogeneous ferromagnetic film by engineering an anisotropy contrast. Substrates with laterally modulated single-crystal and polycrystalline surface regions were used to induce selective epitaxial growth of a ferromagnetic Ni film. The resulting spatially varying magnetic anisotropy leads to regular perpendicular and in-plane magnetic domains, separated by a new type of magnetic wall-the ``anisotropy constrained'' magnetic wall.

  1. Domain-Based Classification of CSCW Systems

    Directory of Open Access Journals (Sweden)

    M. Khan

    2011-11-01

    Full Text Available CSCW systems are widely used for group activities in different organizations and setups. This study briefly describes the existing classifications of CSCW systems and their shortcomings. These existing classifications are helpful to categorize systems based on a general set of CSCW characteristics but do not provide any guidance towards system design and evaluation. After literature review of ACM CSCW conference (1986-2010, a new classification is proposed to categorize CSCW systems on the basis of domains. This proposed classification may help researchers to come up with more effective design and evaluation methods for CSCW systems.

  2. Maximum Probability Domains for Hubbard Models

    CERN Document Server

    Acke, Guillaume; Claeys, Pieter W; Van Raemdonck, Mario; Poelmans, Ward; Van Neck, Dimitri; Bultinck, Patrick

    2015-01-01

    The theory of Maximum Probability Domains (MPDs) is formulated for the Hubbard model in terms of projection operators and generating functions for both exact eigenstates as well as Slater determinants. A fast MPD analysis procedure is proposed, which is subsequently used to analyse numerical results for the Hubbard model. It is shown that the essential physics behind the considered Hubbard models can be exposed using MPDs. Furthermore, the MPDs appear to be in line with what is expected from Valence Bond Theory-based knowledge.

  3. Designing Assistive Technologies for the ADHD Domain

    DEFF Research Database (Denmark)

    Sonne, Tobias; Grønbæk, Kaj

    (ADHD). In this paper, we identify a set of challenges that children with ADHD typically experience, which provides an empirical foundation for pervasive health researchers to address the ADHD domain. The work is grounded in extensive empirical studies and it is contextualized using literature on ADHD....... Based on these studies, we also present lessons learned that are relevant to consider when designing assistive technology to support children with ADHD. Finally, we provide an example (CASTT) of our own work to illustrate how the presented findings can frame research activities and be used to develop...... novel assistive technology to empower children with ADHD and improve their wellbeing....

  4. Effective action of domain wall networks

    International Nuclear Information System (INIS)

    U(NC) gauge theory with NF fundamental scalars admits BPS junctions of domain walls. When the networks/webs of these walls contain loops, their size moduli give localized massless modes. We construct Kaehler potential of their effective action. In the large size limit Kaehler metric is well approximated by kinetic energy of walls and junctions, which is understood in terms of tropical geometry. Kaehler potential can be expressed in terms of hypergeometric functions that are useful to understand small size behavior. Even when the loop shrinks, the metric is regular with positive curvature. Moduli space of a single triangle loop has a geometry between a cone and a cigar

  5. Landauer's principle in the quantum domain

    Directory of Open Access Journals (Sweden)

    Eric Lutz

    2010-06-01

    Full Text Available Recent papers discussing thermodynamic processes in strongly coupled quantum systems claim a violation of Landauer's principle and imply a violation of the second law of thermodynamics. If true, this would have powerful consequences. Perpetuum mobiles could be build as long as the operating temperature is brought close to zero. It would also have serious consequences on thermodynamic derivations of information theoretic results, such as the Holevo bound. Here we argue why these claims are erroneous. Correlations occurring in the strongly coupled, quantum domain require a rethink of how entropy, heat and work are calculated. It is shown that a consistent treatment solves the paradox.

  6. DOMAIN ONTOLOGY DEVELOPMENT FOR COMMUNICABLE DISEASES

    Directory of Open Access Journals (Sweden)

    Iti Mathur

    2013-02-01

    Full Text Available Web has become the very first resource to search for any kind of information. With the emergence of semantic web, our search queries have started generating more informed results. Ontologies are at the core of any semantic web application. They help in rapid development of distributed systems by providing information on the fly. This key feature of distribution and sharing of information has made ontologies as a new knowledge representation mechanism. A mechanism which is strongly backed by a sound inference system. In this paper, we shall discuss the development, verification and validation of an ontology in a health domain.

  7. Constricted nanowire with stabilized magnetic domain wall

    Science.gov (United States)

    Sbiaa, R.; Al Bahri, M.

    2016-08-01

    Domain wall (DW)-based magnetic memory offers the possibility for increasing the storage capacity. However, stability of DW remains the major drawback of this scheme. In this letter, we propose a stepped nanowire for pinning DW in a desirable position. From micromagnetic simulation, the proposed design applied to in-plane magnetic anisotropy materials shows that by adjusting the nanowire step size and its width it is possible to stabilize DW for a desirable current density range. In contrast, only a movement of DW could be seen for conventional nanowire. An extension to a multi-stepped nanowire could be used for multi-bit per cell magnetic memory.

  8. Surface magnetic domains dynamic in machined steel

    Directory of Open Access Journals (Sweden)

    Blažek D.

    2014-07-01

    Full Text Available This contribution deals with an observation of the magnetic dynamic of different types of the machined surface of bearing steel. The Bakhausen noise (BN measurements are presented here as commonly introduced in industry for quality control due to the extremely sensitivity of the magnetic domains wall dynamics to the microstructure of material. The results of magneto-optical measurements are presented with the goal to explain the observed BN anisotropy. It is shown that BN anisotropy is associated with uniaxal magnetic anisotropy introduced by hard milling which causes the principally different magnetic reversals processes in orthogonal directions.

  9. Digital Switching in the Quantum Domain

    OpenAIRE

    Tsai, I. M.; Kuo, S.Y.

    2002-01-01

    In this paper, we present an architecture and implementation algorithm such that digital data can be switched in the quantum domain. First we define the connection digraph which can be used to describe the behavior of a switch at a given time, then we show how a connection digraph can be implemented using elementary quantum gates. The proposed mechanism supports unicasting as well as multicasting, and is strict-sense non-blocking. It can be applied to perform either circuit switching or packe...

  10. Observation of complementarity in the macroscopic domain

    International Nuclear Information System (INIS)

    Complementarity is usually considered as a phenomenon of microscopic systems. In this paper, we report an experimental observation of complementarity in correlated double-slit interference with a pseudothermal light source. The thermal light beam is divided into test and reference beams which are correlated with each other. The double slit is set in the test arm, and an interference pattern can be observed in the intensity correlation between the two arms. The experimental results show that the disappearance of the interference fringe depends on whether which-path information is gained through the reference arm. The experiment therefore shows complementarity occurring in the macroscopic domain

  11. A review of time-domain and frequency-domain component mode synthesis method

    Science.gov (United States)

    Craig, R. R., Jr.

    1985-01-01

    Hurty (1965) has conducted a dynamic analysis of structural systems using component modes. The component mode synthesis (CMS) procedure considered by him represents a form of substructure coupling analysis which is often utilized in structural dynamics. Time-domain CMS methods employing real modes are discussed, taking into account real component modes, normal modes, redundant constraint modes, rigid-body modes, attachment modes, inertia-relief modes, statically-complete interface mode sets, dynamic component mode supersets, component modal models, the coupling of components, and the classification of methods. Attention is also given to the experimental determination of component mode synthesis parameters, time-domain CMS methods for damped systems, and frequency-domain CMS methods for damped systems.

  12. Numerical methods for time-domain and frequency-domain analysis: applications in engineering

    Science.gov (United States)

    Tamas, R. D.

    2015-11-01

    Numerical methods are widely used for modeling different physical phenomena in engineering, especially when an analytic approach is not possible. Time-domain or frequency- domain type variations are generally investigated, depending on the nature of the process under consideration. Some methods originate from mechanics, although most of their applications belong to other fields, such as electromagnetism. Conversely, other methods were firstly developed for electromagnetism, but their field of application was extended to other fields. This paper presents some results that we have obtained by using a general purpose method for solving linear equations, i.e., the method of moments (MoM), and a time-domain method derived for electromagnetism, i.e., the Transmission Line Matrix method (TLM).

  13. Single-domain versus two-domain configuration in thin ferromagnetic prisms

    International Nuclear Information System (INIS)

    Thin ferromagnetic elements in the form of rectangular prisms are theoretically investigated in order to study the transition from single-domain to two-domain state, with changing the in-plane aspect ratio p. We address two main questions: first, how general is the transition; second, how the critical value pc depends on the physical parameters. We use two complementary methods: discrete-lattice calculations and a micromagnetic continuum approach. Ultrathin films do not appear to split in two domains. Instead, thicker films may undergo the above transition. We have used the continuum approach to analyze recent magnetic force microscopy observations in 30nm-thick patterned permalloy elements, finding a good agreement for pc

  14. Feasibility and Domain Validation of Rheumatoid Arthritis (RA) Flare Core Domain Set

    DEFF Research Database (Denmark)

    Bartlett, Susan J; Bykerk, Vivian P; Cooksey, Roxanne;

    2015-01-01

    OBJECTIVE: The Outcome Measures in Rheumatology (OMERACT) Rheumatoid Arthritis (RA) Flare Group was established to develop an approach to identify and measure RA flares. An overview of our OMERACT 2014 plenary is provided. METHODS: Feasibility and validity of flare domains endorsed at OMERACT 11...... (2012) were described based on initial data from 3 international studies collected using a common set of questions specific to RA flare. Mean flare frequency, severity, and duration data were presented, and domain scores were compared by flare status to examine known-groups validity. Breakout groups...... 2 other trials, with similar results. Breakout groups debated specific measurement issues. CONCLUSION: These data contribute initial evidence of feasibility and content validation of the OMERACT RA Flare Core Domain Set. Our research agenda for OMERACT 2016 includes establishing duration...

  15. A Highly Accurate Regular Domain Collocation Method for Solving Potential Problems in the Irregular Doubly Connected Domains

    Directory of Open Access Journals (Sweden)

    Zhao-Qing Wang

    2014-01-01

    Full Text Available Embedding the irregular doubly connected domain into an annular regular region, the unknown functions can be approximated by the barycentric Lagrange interpolation in the regular region. A highly accurate regular domain collocation method is proposed for solving potential problems on the irregular doubly connected domain in polar coordinate system. The formulations of regular domain collocation method are constructed by using barycentric Lagrange interpolation collocation method on the regular domain in polar coordinate system. The boundary conditions are discretized by barycentric Lagrange interpolation within the regular domain. An additional method is used to impose the boundary conditions. The least square method can be used to solve the overconstrained equations. The function values of points in the irregular doubly connected domain can be calculated by barycentric Lagrange interpolation within the regular domain. Some numerical examples demonstrate the effectiveness and accuracy of the presented method.

  16. Frequency domain analysis of knock images

    International Nuclear Information System (INIS)

    High speed imaging-based knock analysis has mainly focused on time domain information, e.g. the spark triggered flame speed, the time when end gas auto-ignition occurs and the end gas flame speed after auto-ignition. This study presents a frequency domain analysis on the knock images recorded using a high speed camera with direct photography in a rapid compression machine (RCM). To clearly visualize the pressure wave oscillation in the combustion chamber, the images were high-pass-filtered to extract the luminosity oscillation. The luminosity spectrum was then obtained by applying fast Fourier transform (FFT) to three basic colour components (red, green and blue) of the high-pass-filtered images. Compared to the pressure spectrum, the luminosity spectra better identify the resonant modes of pressure wave oscillation. More importantly, the resonant mode shapes can be clearly visualized by reconstructing the images based on the amplitudes of luminosity spectra at the corresponding resonant frequencies, which agree well with the analytical solutions for mode shapes of gas vibration in a cylindrical cavity. (paper)

  17. Domain effects and financial risk attitudes.

    Science.gov (United States)

    Vlaev, Ivo; Kusev, Petko; Stewart, Neil; Aldrovandi, Silvio; Chater, Nick

    2010-09-01

    We investigated whether financial risk preferences are dependent on the financial domain (i.e., the context) in which the risky choice options are presented. Previous studies have demonstrated that risk attitudes change when gambles are framed as gains, losses, or as insurance. Our study explores this directly by offering choices between identical gambles, framed in terms of seven financial domains. Three factors were extracted, explaining 68.6% of the variance: Factor 1 (Positive)-opportunity to win, pension provision, and job salary change; Factor 2 (Positive-Complex)-investments and mortgage buying; Factor 3 (Negative)-possibility of loss and insurance. Inspection of the solution revealed context effects on risk perceptions across the seven scenarios. We also found that the commonly accepted assumption that women are more risk averse cannot be confirmed with the context structure suggested in this research; however, it is acknowledged that in the students' population the variance across genders might be considerably less. These results suggest that our financial risk attitude measures may be tapping into a stable aspect of "context dependence" of relevance to real-world decision making. PMID:20840489

  18. Shape Statistics for Random Domains and Particles

    Science.gov (United States)

    Stoyan, Dietrich; Davtyan, Ashot; Turetayev, Daulet

    This paper surveys ideas of statistical analysis of planar images of particles such as powder particles or sand grains, domains such as monolayer domains on water or water droplets on planar surfaces and biological cells or vesicles. For a simple and fast discrimination between collectives of particles, shape ratios or indices such as `area:perimeter' ratio are powerful tools. A more detailed description is possible by means of various functions such as radius-vector function, tangent-angle function and erosion function. A deeper understanding of particle shape and size is possible by studying the relevant physical processes which generate them, such as fracture, abrasion and growth by aggregation. The second part of the paper discusses a particular stochastic model, called Gibbs pixel-particle. It produces two-dimensional connected lattice figures, often called lattice animals, the distribution of which depends on an energy function which is controled by particle area and boundary length and roughness. These pixel-particles vary in a broad spectrum of possible shapes and sizes.

  19. SEMANTIC INFORMATION EXTRACTION IN UNIVERSITY DOMAIN

    Directory of Open Access Journals (Sweden)

    Swathi

    2012-07-01

    Full Text Available Today’s conventional search engines hardly do provide the essential content relevant to the user’s search query. This is because the context and semantics of the request made by the user is not analyzed to the full extent. So here the need for a semantic web search arises. SWS is upcoming in the area of web search which combines Natural Language Processing and Artificial Intelligence. The objective of the work done here is to design, develop and implement a semantic search engine- SIEU(Semantic Information Extraction in University Domain confined to the university domain. SIEU uses ontology as a knowledge base for the information retrieval process. It is not just a mere keyword search. It is one layer above what Google or any other search engines retrieve by analyzing just the keywords. Here the query is analyzed both syntactically and semantically. The developed system retrieves the web results more relevant to the user query through keyword expansion. The results obtained here will be accurate enough to satisfy the request made by the user. The level of accuracy will be enhanced since the query is analyzed semantically. The system will be of great use to the developers and researchers who work on web. The Google results are re-ranked and optimized for providing the relevant links. For ranking an algorithm has been applied which fetches more apt results for the user query.

  20. Spectral fusing Gabor domain optical coherence microscopy.

    Science.gov (United States)

    Meemon, Panomsak; Widjaja, Joewono; Rolland, Jannick P

    2016-02-01

    Gabor domain optical coherence microscopy (GD-OCM) is one of many variations of optical coherence tomography (OCT) techniques that aims for invariant high resolution across a 3D field of view by utilizing the ability to dynamically refocus the imaging optics in the sample arm. GD-OCM acquires multiple cross-sectional images at different focus positions of the objective lens, and then fuses them to obtain an invariant high-resolution 3D image of the sample, which comes with the intrinsic drawback of a longer processing time as compared to conventional Fourier domain OCT. Here, we report on an alternative Gabor fusing algorithm, the spectral-fusion technique, which directly processes each acquired spectrum and combines them prior to the Fourier transformation to obtain a depth profile. The implementation of the spectral-fusion algorithm is presented and its performance is compared to that of the prior GD-OCM spatial-fusion approach. The spectral-fusion approach shows twice the speed of the spatial-fusion approach for a spectrum size of less than 2000 point sampling, which is a commonly used spectrum size in OCT imaging, including GD-OCM. PMID:26907410

  1. Multiply connected wandering domains of entire functions

    CERN Document Server

    Bergweiler, Walter; Stallard, Gwyneth M

    2011-01-01

    The dynamical behaviour of a transcendental entire function in any periodic component of the Fatou set is well understood. Here we study the dynamical behaviour of a transcendental entire function $f$ in any multiply connected wandering domain $U$ of $f$. By introducing a certain positive harmonic function $h$ in $U$, related to harmonic measure, we are able to give the first detailed description of this dynamical behaviour. Using this new technique, we show that, for sufficiently large $n$, the image domains $U_n=f^n(U)$ contain large annuli, $C_n$, and that the union of these annuli acts as an absorbing set for the iterates of $f$ in $U$. Moreover, $f$ behaves like a monomial within each of these annuli and the orbits of points in $U$ settle in the long term at particular `levels' within the annuli, determined by the function $h$. We also discuss the proximity of $\\partial U_n$ and $\\partial C_n$ for large $n$, and the connectivity properties of the components of $U_n \\setminus \\bar{C_n}$. These properties ...

  2. Microdissection of shoot meristem functional domains.

    Directory of Open Access Journals (Sweden)

    Lionel Brooks

    2009-05-01

    Full Text Available The shoot apical meristem (SAM maintains a pool of indeterminate cells within the SAM proper, while lateral organs are initiated from the SAM periphery. Laser microdissection-microarray technology was used to compare transcriptional profiles within these SAM domains to identify novel maize genes that function during leaf development. Nine hundred and sixty-two differentially expressed maize genes were detected; control genes known to be upregulated in the initiating leaf (P0/P1 or in the SAM proper verified the precision of the microdissections. Genes involved in cell division/growth, cell wall biosynthesis, chromatin remodeling, RNA binding, and translation are especially upregulated in initiating leaves, whereas genes functioning during protein fate and DNA repair are more abundant in the SAM proper. In situ hybridization analyses confirmed the expression patterns of six previously uncharacterized maize genes upregulated in the P0/P1. P0/P1-upregulated genes that were also shown to be downregulated in leaf-arrested shoots treated with an auxin transport inhibitor are especially implicated to function during early events in maize leaf initiation. Reverse genetic analyses of asceapen1 (asc1, a maize D4-cyclin gene upregulated in the P0/P1, revealed novel leaf phenotypes, less genetic redundancy, and expanded D4-CYCLIN function during maize shoot development as compared to Arabidopsis. These analyses generated a unique SAM domain-specific database that provides new insight into SAM function and a useful platform for reverse genetic analyses of shoot development in maize.

  3. Inflationary power asymmetry from primordial domain walls

    International Nuclear Information System (INIS)

    We study the asymmetric primordial fluctuations in a model of inflation in which translational invariance is broken by a domain wall. We calculate the corrections to the power spectrum of curvature perturbations; they are anisotropic and contain dipole, quadrupole, and higher multipoles with non-trivial scale-dependent amplitudes. Inspired by observations of these multipole asymmetries in terms of two-point correlations and variance in real space, we demonstrate that this model can explain the observed anomalous power asymmetry of the cosmic microwave background (CMB) sky, including its characteristic feature that the dipole dominates over higher multipoles. We test the viability of the model and place approximate constraints on its parameters by using observational values of dipole, quadrupole, and octopole amplitudes of the asymmetry measured by a local-variance estimator. We find that a configuration of the model in which the CMB sphere does not intersect the domain wall during inflation provides a good fit to the data. We further derive analytic expressions for the corrections to the CMB temperature covariance matrix, or angular power spectra, which can be used in future statistical analysis of the model in spherical harmonic space

  4. Irregular Homogeneity Domains in Ternary Intermetallic Systems

    Directory of Open Access Journals (Sweden)

    Jean-Marc Joubert

    2015-12-01

    Full Text Available Ternary intermetallic A–B–C systems sometimes have unexpected behaviors. The present paper examines situations in which there is a tendency to simultaneously form the compounds ABx, ACx and BCx with the same crystal structure. This causes irregular shapes of the phase homogeneity domains and, from a structural point of view, a complete reversal of site occupancies for the B atom when crossing the homogeneity domain. This work reviews previous studies done in the systems Fe–Nb–Zr, Hf–Mo–Re, Hf–Re–W, Mo–Re–Zr, Re–W–Zr, Cr–Mn–Si, Cr–Mo–Re, and Mo–Ni–Re, and involving the topologically close-packed Laves, χ and σ phases. These systems have been studied using ternary isothermal section determination, DFT calculations, site occupancy measurement using joint X-ray, and neutron diffraction Rietveld refinement. Conclusions are drawn concerning this phenomenon. The paper also reports new experimental or calculated data on Co–Cr–Re and Fe–Nb–Zr systems.

  5. Accelerating advances in continental domain hydrologic modeling

    Science.gov (United States)

    Archfield, Stacey A.; Clark, Martyn; Arheimer, Berit; Hay, Lauren E.; McMillan, Hilary; Kiang, Julie E.; Seibert, Jan; Hakala, Kirsti; Bock, Andrew; Wagener, Thorsten; Farmer, William H.; Andréassian, Vazken; Attinger, Sabine; Viglione, Alberto; Knight, Rodney; Markstrom, Steven; Over, Thomas

    2015-12-01

    In the past, hydrologic modeling of surface water resources has mainly focused on simulating the hydrologic cycle at local to regional catchment modeling domains. There now exists a level of maturity among the catchment, global water security, and land surface modeling communities such that these communities are converging toward continental domain hydrologic models. This commentary, written from a catchment hydrology community perspective, provides a review of progress in each community toward this achievement, identifies common challenges the communities face, and details immediate and specific areas in which these communities can mutually benefit one another from the convergence of their research perspectives. Those include: (1) creating new incentives and infrastructure to report and share model inputs, outputs, and parameters in data services and open access, machine-independent formats for model replication or reanalysis; (2) ensuring that hydrologic models have: sufficient complexity to represent the dominant physical processes and adequate representation of anthropogenic impacts on the terrestrial water cycle, a process-based approach to model parameter estimation, and appropriate parameterizations to represent large-scale fluxes and scaling behavior; (3) maintaining a balance between model complexity and data availability as well as uncertainties; and (4) quantifying and communicating significant advancements toward these modeling goals.

  6. Natural Language Question Answering in Open Domains

    Directory of Open Access Journals (Sweden)

    Dan Tufis

    2011-10-01

    Full Text Available With the ever-growing volume of information on the web, the traditional search engines, returning hundreds or thousands of documents per query, become more and more demanding on the user patience in satisfying his/her information needs. Question Answering in Open Domains is a top research and development topic in current language technology. Unlike the standard search engines, based on the latest Information Retrieval (IR methods, open domain question-answering systems are expected to deliver not a list of documents that might be relevant for the user's query, but a sentence or a paragraph answering the question asked in natural language. This paper reports on the construction and testing of a Question Answering (QA system which builds on several web services developed at the Research Institute for Artificial Intelligence (ICIA/RACAI. The evaluation of the system has been independently done by the organizers of the ResPubliQA 2009 exercise and has been rated the best performing system with the highest improvement due to the natural language processing technology over a baseline state-of-the-art IR system. The system was trained on a specific corpus, but its functionality is independent on the linguistic register of the training data.

  7. Domain-General and Domain-Specific Creative-Thinking Tests: Effects of Gender and Item Content on Test Performance

    Science.gov (United States)

    Hong, Eunsook; Peng, Yun; O'Neil, Harold F., Jr.; Wu, Junbin

    2013-01-01

    The study examined the effects of gender and item content of domain-general and domain-specific creative-thinking tests on four subscale scores of creative-thinking (fluency, flexibility, originality, and elaboration). Chinese tenth-grade students (234 males and 244 females) participated in the study. Domain-general creative thinking was measured…

  8. Augmenting ALC(D) (atemporal) roles and (aspatial) concrete domain with temporal roles and a spatial concrete domain -first results

    OpenAIRE

    Isli, Amar

    2004-01-01

    We consider the well-known family ALC(D) of description logics with a concrete domain, and provide first results on a framework obtained by augmenting ALC(D) atemporal roles and aspatial concrete domain with temporal roles and a spatial concrete domain.

  9. Recovering protein-protein and domain-domain interactions from aggregation of IP-MS proteomics of coregulator complexes.

    Directory of Open Access Journals (Sweden)

    Amin R Mazloom

    2011-12-01

    Full Text Available Coregulator proteins (CoRegs are part of multi-protein complexes that transiently assemble with transcription factors and chromatin modifiers to regulate gene expression. In this study we analyzed data from 3,290 immuno-precipitations (IP followed by mass spectrometry (MS applied to human cell lines aimed at identifying CoRegs complexes. Using the semi-quantitative spectral counts, we scored binary protein-protein and domain-domain associations with several equations. Unlike previous applications, our methods scored prey-prey protein-protein interactions regardless of the baits used. We also predicted domain-domain interactions underlying predicted protein-protein interactions. The quality of predicted protein-protein and domain-domain interactions was evaluated using known binary interactions from the literature, whereas one protein-protein interaction, between STRN and CTTNBP2NL, was validated experimentally; and one domain-domain interaction, between the HEAT domain of PPP2R1A and the Pkinase domain of STK25, was validated using molecular docking simulations. The scoring schemes presented here recovered known, and predicted many new, complexes, protein-protein, and domain-domain interactions. The networks that resulted from the predictions are provided as a web-based interactive application at http://maayanlab.net/HT-IP-MS-2-PPI-DDI/.

  10. Peer Review-Based Scripted Collaboration to Support Domain-Specific and Domain-General Knowledge Acquisition in Computer Science

    Science.gov (United States)

    Demetriadis, Stavros; Egerter, Tina; Hanisch, Frank; Fischer, Frank

    2011-01-01

    This study investigates the effectiveness of using peer review in the context of scripted collaboration to foster both domain-specific and domain-general knowledge acquisition in the computer science domain. Using a one-factor design with a script and a control condition, students worked in small groups on a series of computer science problems…

  11. A new characterization of chord-arc domains

    OpenAIRE

    Azzam, Jonas; Hofmann, Steve; Martell, José María; Nyström, Kaj; Toro, Tatiana

    2014-01-01

    We show that if $\\Omega \\subset \\mathbb{R}^{n+1}$, $n\\geq 1$, is a uniform domain (aka 1-sided NTA domain), i.e., a domain which enjoys interior Corkscrew and Harnack Chain conditions, then uniform rectifiability of the boundary of $\\Omega$ implies the existence of exterior Corkscrew points at all scales, so that in fact, $\\Omega$ is a chord-arc domain, i.e., a domain with an Ahlfors-David regular boundary which satisfies both interior and exterior Corkscrew conditions, and an interior Harnac...

  12. Evolutionary cores of domain co-occurrence networks

    Directory of Open Access Journals (Sweden)

    Almaas Eivind

    2005-03-01

    Full Text Available Abstract Background The modeling of complex systems, as disparate as the World Wide Web and the cellular metabolism, as networks has recently uncovered a set of generic organizing principles: Most of these systems are scale-free while at the same time modular, resulting in a hierarchical architecture. The structure of the protein domain network, where individual domains correspond to nodes and their co-occurrences in a protein are interpreted as links, also falls into this category, suggesting that domains involved in the maintenance of increasingly developed, multicellular organisms accumulate links. Here, we take the next step by studying link based properties of the protein domain co-occurrence networks of the eukaryotes S. cerevisiae, C. elegans, D. melanogaster, M. musculus and H. sapiens. Results We construct the protein domain co-occurrence networks from the PFAM database and analyze them by applying a k-core decomposition method that isolates the globally central (highly connected domains in the central cores from the locally central (highly connected domains in the peripheral cores protein domains through an iterative peeling process. Furthermore, we compare the subnetworks thus obtained to the physical domain interaction network of S. cerevisiae. We find that the innermost cores of the domain co-occurrence networks gradually grow with increasing degree of evolutionary development in going from single cellular to multicellular eukaryotes. The comparison of the cores across all the organisms under consideration uncovers patterns of domain combinations that are predominately involved in protein functions such as cell-cell contacts and signal transduction. Analyzing a weighted interaction network of PFAM domains of Yeast, we find that domains having only a few partners frequently interact with these, while the converse is true for domains with a multitude of partners. Combining domain co-occurrence and interaction information, we observe

  13. SINGLE IMAGE SUPER RESOLUTION IN SPATIAL AND WAVELET DOMAIN

    Directory of Open Access Journals (Sweden)

    Sapan Naik

    2013-08-01

    Full Text Available Recently single image super resolution is very important research area to generate high-resolution image from given low-resolution image. Algorithms of single image resolution are mainly based on wavelet domain and spatial domain. Filter’s support to model the regularity of natural images is exploited in wavelet domain while edges of images get sharp during up sampling in spatial domain. Here single image super resolution algorithm is presented which based on both spatial and wavelet domain and take the advantage of both. Algorithm is iterative and use back projection to minimize reconstruction error. Wavelet based denoising method is also introduced to remove noise.

  14. Formal Ontology: Foundation of Domain Knowledge Sharing and Reusing

    Institute of Scientific and Technical Information of China (English)

    陆汝钤; 金芝

    2002-01-01

    Domain analysis is the activity of identifying and representing the relevantinformation in a domain, so that the information can be shared and reused in similar systems.But until now, no efficient approaches are available for capturing and representing the results ofdomain analysis and then for sharing and reusing the domain knowledge. This paper proposesan ontology-oriented approach for formalizing the domain models. The architecture for themultiple-layer structure of the domain knowledge base is also discussed. And finally, somegenetic algorithm-based methods have been given for supporting the knowledge sharing andreusing.

  15. Nanoscale domain switching behaviour in polycrystalline ferroelectric thin films

    International Nuclear Information System (INIS)

    We report on the nanoscale domain switching behaviour in polycrystalline tetragonal perovskite lead zirconate titanate (PZT) ferroelectric thin films investigated via piezoresponse force microscopy (PFM). Local domain structures were imaged as a function of varying biasing conditions and spatial location of the tip within 50-100 nm sized grains. Nanoscale piezoresponse images provided direct visual evidence of the complex interplay between electrical and mechanical fields in a polycrystalline system, which causes effects such as correlated switching between the grain of interest and neighbouring grains, ferroelastic domain switching, inhomogeneous piezostrain profiles and domain pinning on very minute length scales. Detailed investigations on mechanisms which induce such domain behaviour are presented

  16. Domain Engineering - A Software Engineering discipline in Need of Research

    DEFF Research Database (Denmark)

    Bjørner, Dines

    2000-01-01

    Before software can be developed its requirements must be stated. Before requirements can be expressed the application domain must be understood. In this paper we outline some of the basic facets of domain engineering. Domains seem, it is our experience, far more stable than computing requirements......, and these again seem more stable than software designs. Thus, almost like the universal laws of physics, it pays off to first develop theories of domains. But domain engineering, as in fact also requirements engineering, really is in need of thoroughly researched development principles, techniques and...

  17. Domain Adaptation for Opinion Classification: A Self-Training Approach

    Directory of Open Access Journals (Sweden)

    Yu, Ning

    2013-03-01

    Full Text Available Domain transfer is a widely recognized problem for machine learning algorithms because models built upon one data domain generally do not perform well in another data domain. This is especially a challenge for tasks such as opinion classification, which often has to deal with insufficient quantities of labeled data. This study investigates the feasibility of self-training in dealing with the domain transfer problem in opinion classification via leveraging labeled data in non-target data domain(s and unlabeled data in the target-domain. Specifically, self-training is evaluated for effectiveness in sparse data situations and feasibility for domain adaptation in opinion classification. Three types of Web content are tested: edited news articles, semi-structured movie reviews, and the informal and unstructured content of the blogosphere. Findings of this study suggest that, when there are limited labeled data, self-training is a promising approach for opinion classification, although the contributions vary across data domains. Significant improvement was demonstrated for the most challenging data domain-the blogosphere-when a domain transfer-based self-training strategy was implemented.

  18. Reuse of structural domain–domain interactions in protein networks

    Directory of Open Access Journals (Sweden)

    Bateman Alex

    2007-07-01

    Full Text Available Abstract Background Protein interactions are thought to be largely mediated by interactions between structural domains. Databases such as iPfam relate interactions in protein structures to known domain families. Here, we investigate how the domain interactions from the iPfam database are distributed in protein interactions taken from the HPRD, MPact, BioGRID, DIP and IntAct databases. Results We find that known structural domain interactions can only explain a subset of 4–19% of the available protein interactions, nevertheless this fraction is still significantly bigger than expected by chance. There is a correlation between the frequency of a domain interaction and the connectivity of the proteins it occurs in. Furthermore, a large proportion of protein interactions can be attributed to a small number of domain interactions. We conclude that many, but not all, domain interactions constitute reusable modules of molecular recognition. A substantial proportion of domain interactions are conserved between E. coli, S. cerevisiae and H. sapiens. These domains are related to essential cellular functions, suggesting that many domain interactions were already present in the last universal common ancestor. Conclusion Our results support the concept of domain interactions as reusable, conserved building blocks of protein interactions, but also highlight the limitations currently imposed by the small number of available protein structures.

  19. Soliton-dependent plasmon reflection at bilayer graphene domain walls

    Science.gov (United States)

    Jiang, Lili; Shi, Zhiwen; Zeng, Bo; Wang, Sheng; Kang, Ji-Hun; Joshi, Trinity; Jin, Chenhao; Ju, Long; Kim, Jonghwan; Lyu, Tairu; Shen, Yuen-Ron; Crommie, Michael; Gao, Hong-Jun; Wang, Feng

    2016-08-01

    Layer-stacking domain walls in bilayer graphene are emerging as a fascinating one-dimensional system that features stacking solitons structurally and quantum valley Hall boundary states electronically. The interactions between electrons in the 2D graphene domains and the one-dimensional domain-wall solitons can lead to further new quantum phenomena. Domain-wall solitons of varied local structures exist along different crystallographic orientations, which can exhibit distinct electrical, mechanical and optical properties. Here we report soliton-dependent 2D graphene plasmon reflection at different 1D domain-wall solitons in bilayer graphene using near-field infrared nanoscopy. We observe various domain-wall structures in mechanically exfoliated graphene bilayers, including network-forming triangular lattices, individual straight or bent lines, and even closed circles. The near-field infrared contrast of domain-wall solitons arises from plasmon reflection at domain walls, and exhibits markedly different behaviours at the tensile- and shear-type domain-wall solitons. In addition, the plasmon reflection at domain walls exhibits a peculiar dependence on electrostatic gating. Our study demonstrates the unusual and tunable coupling between 2D graphene plasmons and domain-wall solitons.

  20. Bilayer thickness mismatch controls domain size in biomimetic membranes

    Science.gov (United States)

    Heberle, Frederick A.; Petruzielo, Robin S.; Pan, Jianjun; Drazba, Paul; Kučerka, Norbert; Standaert, Robert F.; Feigenson, Gerald W.; Katsara, John

    2013-03-01

    In order to promote functionality, cells may alter the spatial organization of membrane lipids and proteins, including separation of liquid phases into distinct domains. In model membranes, domain size and morphology depend strongly on composition and temperature, but the physicochemical mechanisms controlling them are poorly understood. Theoretical work suggests a role for interfacial energy at domain boundaries, which may be driven in part by thickness mismatch between a domain and its surrounding bilayer. However, no direct evidence linking thickness mismatch to domain size in free-standing bilayers has been reported. We describe the use of Small Angle Neutron Scattering (SANS) to detect domains in simplified lipid-only models that mimic the composition of plasma membrane. We find that domain size is controlled by the degree of acyl chain unsaturation of low-melting temperature lipids, and that this size transition is correlated to changes in the thickness mismatch between coexisting liquid phases.

  1. Concept of the field-driven domain wall motion memory

    International Nuclear Information System (INIS)

    In this paper, the concept of field-driven domain wall motion memory is presented. It is confirmed that a domain is shifted with a carefully designed non-uniform field by micromagnetic simulations. The shift of a domain-a bit-can be established by the motion of two domain walls to the same direction and the same distance. In order to get a better understanding of the domain wall motion under the non-uniform transverse magnetic field, we investigate the motion of the transverse Neel-type domain wall by micromagnetic simulations and the collective coordinate approach. The validity of the equation of motion for the domain wall is confirmed by the micromagnetic simulations as functions of the gradient of the non-uniform field, the saturation magnetization, and the Gilbert damping parameter α

  2. Localization of Laplacian eigenfunctions in circular, spherical and elliptical domains

    CERN Document Server

    Nguyen, Binh-Thanh

    2012-01-01

    We consider Laplacian eigenfunctions in circular, spherical and elliptical domains in order to discuss three kinds of high-frequency localization: whispering gallery modes, bouncing ball modes, and focusing modes. Although the existence of these modes was known for a class of convex domains, the separation of variables for above domains helps to better understand the "mechanism" of localization, i.e. how an eigenfunction is getting distributed in a small region of the domain, and decays rapidly outside this region. Using the properties of Bessel and Mathieu functions, we derive the inequalities which imply and clearly illustrate localization. Moreover, we provide an example of a non-convex domain (an elliptical annulus) for which the high-frequency localized modes are still present. At the same time, we show that there is no localization in most of rectangle-like domains. This observation leads us to formulating an open problem of localization in polygonal domains and, more generally, in piecewise smooth conv...

  3. Beamforming in Short Time Fractional Fourier Domain (FRFD

    Directory of Open Access Journals (Sweden)

    Mostafa Rahmani

    2012-09-01

    Full Text Available This study aims to generate a model for the problem of beamforming in fractional Fourier domain, through which a general solution for obtaining weighted beamforming in fractional Fourier domain for different criteria might be delivered. In order to generate this model, a description of fractional delay concept is presented, through which the string vector in fractional Fourier domain is calculated and a model for beamforming in fractional Fourier domain is generated which is similar to that used for obtaining weighted beamforming in time domain for narrow-band signals. To complement our solution, a method for obtaining the optimal fractional domain as well as direction of arrival in optimal fractional Fourier domain.

  4. Thermal stability of bubble domains in ferromagnetic discs

    International Nuclear Information System (INIS)

    The transition and thermal stability of disc-shaped ferromagnetic particles at the temperature of T = 300 K with a uniaxial anisotropy along the symmetry axis from a bi-domain to a single domain state has been studied. The nudge elastic band method was used to map the energy landscape and to calculate the energy barrier between the transition states. For single FePt disc-shaped particles with perpendicular anisotropy three transition configurations have been found: single domain, stripe- and stable bubble domains at zero applied field. The single domain configuration along the positive anisotropy axis is reached by an annihilation process of the domain wall and the all-down state by a complex domain expansion process. Magnetization configurations in two interacting discs show an increase in thermal stability compared with single disc systems, which is attributed to the interacting magnetostatic energy between the two particles

  5. Domain Walls and Vortices in Chiral Symmetry Breaking

    CERN Document Server

    Eto, Minoru; Nitta, Muneto

    2013-01-01

    We study domain walls and vortices in chiral symmetry breaking in QCD with N flavors in the chiral limit. If the axial anomaly was absent, there exist stable Abelian axial vortices winding around the spontaneously broken U(1)_A symmetry and non-Abelian axial vortices winding around both the U(1)_A and non-Abelian SU(N) chiral symmetries. In the presence of the axial anomaly term, metastable domain walls are present and Abelian axial vortices must be attached by N domain walls, forming domain wall junctions. We show that a domain wall junction decays into N non-Abelian vortices attached by domain walls, implying its metastability. We also show that domain walls decay through the quantum tunneling by creating a hole bounded by a closed non-Abelian vortex.

  6. Conformational instability of the MARK3 UBA domain compromises ubiquitin recognition and promotes interaction with the adjacent kinase domain

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, James M.; Korzhnev, Dmitry M.; Ceccarelli, Derek F.; Briant, Douglas J.; Zarrine-Afsar, Arash; Sicheri, Frank; Kay, Lewis E.; Pawson, Tony (Mount Sinai Hospital); (Toronto)

    2012-10-23

    The Par-1/MARK protein kinases play a pivotal role in establishing cellular polarity. This family of kinases contains a unique domain architecture, in which a ubiquitin-associated (UBA) domain is located C-terminal to the kinase domain. We have used a combination of x-ray crystallography and NMR dynamics experiments to understand the interaction of the human (h) MARK3 UBA domain with the adjacent kinase domain as compared with ubiquitin. The x-ray crystal structure of the linked hMARK3 kinase and UBA domains establishes that the UBA domain forms a stable intramolecular interaction with the N-terminal lobe of the kinase domain. However, solution-state NMR studies of the isolated UBA domain indicate that it is highly dynamic, undergoing conformational transitions that can be explained by a folding-unfolding equilibrium. NMR titration experiments indicated that the hMARK3 UBA domain has a detectable but extremely weak affinity for mono ubiquitin, which suggests that conformational instability of the isolated hMARK3 UBA domain attenuates binding to ubiquitin despite the presence of residues typically involved in ubiquitin recognition. Our data identify a molecular mechanism through which the hMARK3 UBA domain has evolved to bind the kinase domain, in a fashion that stabilizes an open conformation of the N- and C-terminal lobes, at the expense of its capacity to engage ubiquitin. These results may be relevant more generally to the 30% of UBA domains that lack significant ubiquitin-binding activity, and they suggest a unique mechanism by which interaction domains may evolve new binding properties.

  7. Domain-and species-specific monoclonal antibodies recognize the Von Willebrand Factor-C domain of CCN5.

    Science.gov (United States)

    Wei, Lan; McKeon, Frank; Russo, Joshua W; Lemire, Joan; Castellot, John

    2009-03-01

    The CCN family of proteins typically consists of four distinct peptide domains: an insulin-like growth factor binding protein-type (IGFBP) domain, a Von Willebrand Factor C (VWC) domain, a thrombospondin type 1 repeat (TSP1) domain, and a carboxy-terminal (CT) domain. The six family members participate in many processes, including proliferation, motility, cell-matrix signaling, angiogenesis, and wound healing. Accumulating evidence suggests that truncated and alternatively spliced isoforms are responsible for the diverse functions of CCN proteins in both normal and pathophysiologic states. Analysis of the properties and functions of individual CCN domains further corroborates this idea. CCN5 is unique among the CCN family members because it lacks the CT-domain. To dissect the domain functions of CCN5, we are developing domain-specific mouse monoclonal antibodies. Monoclonal antibodies have the advantages of great specificity, reproducibility, and ease of long-term storage and production. In this communication, we injected mixtures of GST-fused rat CCN5 domains into mice to generate monoclonal antibodies. To identify the domains recognized by the antibodies, we constructed serial expression plasmids that express dual-tagged rat CCN5 domains. All of the monoclonal antibodies generated to date recognize the VWC domain, indicating it is the most highly immunogenic of the CCN5 domains. We characterized one particular clone, 22H10, and found that it recognizes mouse and rat CCN5, but not human recombinant CCN5. Purified 22H10 was successfully applied in Western Blot analysis, immunofluorescence of cultured cells and tissues, and immunoprecipitation, indicating that it will be a useful tool for domain analysis and studies of mouse-human tumor models. PMID:19401828

  8. The Aretaic Domain and Its Relation to the Deontic Domain in Moral Reasoning.

    Science.gov (United States)

    Lourenco, Orlando

    2000-01-01

    Investigates the ways in which young adults make judgments about two contrasting kinds of rights: moral worthiness (the aretaic) and moral obligation (the deontic), reflecting on how thinking in these areas may be coordinated with responsibility judgments and behavior. Discusses what might be gained if the aretaic domain were taken into account in…

  9. Particle Communication and Domain Neighbor Coupling: Scalable Domain Decomposed Algorithms for Monte Carlo Particle Transport

    International Nuclear Information System (INIS)

    In order to run Monte Carlo particle transport calculations on new supercomputers with hundreds of thousands or millions of processors, care must be taken to implement scalable algorithms. This means that the algorithms must continue to perform well as the processor count increases. In this paper, we examine the scalability of: (1) globally resolving the particle locations on the correct processor, (2) deciding that particle streaming communication has finished, and (3) efficiently coupling neighbor domains together with different replication levels. We have run domain decomposed Monte Carlo particle transport on up to 221 = 2,097,152 MPI processes on the IBM BG/Q Sequoia supercomputer and observed scalable results that agree with our theoretical predictions. These calculations were carefully constructed to have the same amount of work on every processor, i.e. the calculation is already load balanced. We also examine load imbalanced calculations where each domain's replication level is proportional to its particle workload. In this case we show how to efficiently couple together adjacent domains to maintain within workgroup load balance and minimize memory usage.

  10. Fluorescence lifetime detection in turbid media using spatial frequency domain filtering of time domain measurements

    OpenAIRE

    Kumar, Anand T. N.

    2013-01-01

    It is demonstrated that high spatial frequency filtering of time domain fluorescence signals can allow efficient detection of intrinsic fluorescence lifetimes from turbid media and the rejection of diffuse excitation leakage. The basis of this approach is the separation of diffuse fluorescence signals into diffuse and fluorescent components with distinct spatiotemporal behavior.

  11. Examining the Domain-Specificity of Metacognition Using Academic Domains and Task-Specific Individual Differences

    Science.gov (United States)

    Scott, Brianna M.; Berman, Ashleigh F.

    2013-01-01

    Metacognition refers to students' knowledge and regulation of cognition, as well as their accuracy in predicting their academic performance. This study addressed two major questions: 1) how do metacognitive knowledge, regulation and accuracy differ across domains?, and 2) how do students' individual differences relate to their reported…

  12. Communicating oscillatory networks: frequency domain analysis

    Directory of Open Access Journals (Sweden)

    Ihekwaba Adaoha EC

    2011-12-01

    Full Text Available Abstract Background Constructing predictive dynamic models of interacting signalling networks remains one of the great challenges facing systems biology. While detailed dynamical data exists about individual pathways, the task of combining such data without further lengthy experimentation is highly nontrivial. The communicating links between pathways, implicitly assumed to be unimportant and thus excluded, are precisely what become important in the larger system and must be reinstated. To maintain the delicate phase relationships between signals, signalling networks demand accurate dynamical parameters, but parameters optimised in isolation and under varying conditions are unlikely to remain optimal when combined. The computational burden of estimating parameters increases exponentially with increasing system size, so it is crucial to find precise and efficient ways of measuring the behaviour of systems, in order to re-use existing work. Results Motivated by the above, we present a new frequency domain-based systematic analysis technique that attempts to address the challenge of network assembly by defining a rigorous means to quantify the behaviour of stochastic systems. As our focus we construct a novel coupled oscillatory model of p53, NF-kB and the mammalian cell cycle, based on recent experimentally verified mathematical models. Informed by online databases of protein networks and interactions, we distilled their key elements into simplified models containing the most significant parts. Having coupled these systems, we constructed stochastic models for use in our frequency domain analysis. We used our new technique to investigate the crosstalk between the components of our model and measure the efficacy of certain network-based heuristic measures. Conclusions We find that the interactions between the networks we study are highly complex and not intuitive: (i points of maximum perturbation do not necessarily correspond to points of maximum

  13. IMGT unique numbering for MHC groove G-DOMAIN and MHC superfamily (MhcSF) G-LIKE-DOMAIN

    DEFF Research Database (Denmark)

    Lefranc, Marie-Paule; Duprat, E.; Kaas, Quentin;

    2005-01-01

    unique numbering leads, for the first time, to the standardized description of the mutations, allelic polymorphisms, two-dimensional (2D) representations and three-dimensional (3D) structures of the G-DOMAINs and G-LIKE-DOMAINs in any species, and therefore, is highly valuable for their comparative...... immune system (RPI) of human and other vertebrates. The NUMEROTATION concept of IMGT-ONTOLOGY has allowed to define a unique numbering for the variable domains (V-DOMAINs) and constant domains (C-DOMAINs) of the IG and TR, which has been extended to the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the...... immunoglobulin superfamily (IgSF) proteins other than the IG and TR (Dev Comp Immunol 27:55-77, 2003; 29:185-203, 2005). In this paper, we describe the IMGT unique numbering for the groove domains (G-DOMAINs) of the MHC and for the G-LIKE-DOMAINs of the MHC superfamily (MhcSF) proteins other than MHC. This IMGT...

  14. The X-ray structures of two mutant crystallin domains shed light on the evolution of multi-domain proteins.

    Science.gov (United States)

    Norledge, B V; Mayr, E M; Glockshuber, R; Bateman, O A; Slingsby, C; Jaenicke, R; Driessen, H P

    1996-03-01

    We use protein engineering and crystallography to simulate aspects of the early evolution of beta gamma-crystallins by observing how a single domain oligomerizes in response to changes in a sequence extension. The crystal structure of the C-terminal domain of gamma beta-crystallin with its four-residue C-terminal extension shows that the domain does not form a symmetric homodimer analogous to the two-domain pairing in beta gamma-crystallins. Instead the C-terminal extension now forms heterologous interactions with other domains leading to the solvent exposure of the natural hydrophobic interface with a consequent loss in protein solubility. However, this domain truncated by just the C-terminal tyrosine forms a symmetric homodimer of domains in the crystal lattice. PMID:8605629

  15. Magnetic domain and domain-wall imaging of submicron Co dots by probing the magnetostrictive response using atomic force microscopy

    International Nuclear Information System (INIS)

    An approach to image the domains and domain walls of small ferromagnetic entities using atomic force microscopy (AFM), with a nonmagnetic AFM probe, has been developed. Exciting the sample in an external ac magnetic field, the distribution of magnetostrictive response at the surface is detected. By this technique, the domains and domain walls of submicron Co dots have been imaged with a 1 nm lateral resolution. In elliptical Co dots with a 350-nm-long axis on a triangular lattice array with 400 nm periodicity, we find evidence for two domains with opposite magnetization orientation across a wall. The domain-wall width in these dots is found to be about 35 nm. Furthermore, we observe a ferromagnetic alignment of the domains in the neighboring dots, which suggests a magnetostatic interaction among the dots. (c) 2000 American Institute of Physics

  16. Gravitational Waves and Time Domain Astronomy

    Science.gov (United States)

    Centrella, Joan; Nissanke, Samaya; Williams, Roy

    2012-01-01

    The gravitational wave window onto the universe will open in roughly five years, when Advanced LIGO and Virgo achieve the first detections of high frequency gravitational waves, most likely coming from compact binary mergers. Electromagnetic follow-up of these triggers, using radio, optical, and high energy telescopes, promises exciting opportunities in multi-messenger time domain astronomy. In the decade, space-based observations of low frequency gravitational waves from massive black hole mergers, and their electromagnetic counterparts, will open up further vistas for discovery. This two-part workshop featured brief presentations and stimulating discussions on the challenges and opportunities presented by gravitational wave astronomy. Highlights from the workshop, with the emphasis on strategies for electromagnetic follow-up, are presented in this report.

  17. MPEG-4 AVC domain watermarking transparency

    Science.gov (United States)

    Duta, S.; Mitrea, M.; Prêteux, F.; Belhaj, M.

    2008-04-01

    The ever-increasing Internet distribution of video content is echoed in ever-increasing efforts to devise systems balancing copyright protection and user rights. Watermarking is such an example: by persistently and imperceptibly associating some data with the host video, it offers at the same time a reliable and user-friendly solution for copyright infringement tracking. This paper takes a closer look at the apparent contradiction between watermarking (using the visual redundancy of the video to embed the data) and compression (eliminating the visual redundancy in order to speed up distribution and to alleviate storage requirements). In this respect, the viability of compressed domain watermarking is evaluated by analysing the visual effects of the MPEG-4 AVC stream alteration. The corpus consists of 10 video sequences of about 25 minutes each, coded at 256kbps and 64 kbps.

  18. Effective Action of Domain Wall Networks

    CERN Document Server

    Eto, M; Nagashima, T; Nitta, M; Ohashi, K; Sakai, N; Eto, Minoru; Fujimori, Toshiaki; Nagashima, Takayuki; Nitta, Muneto; Ohashi, Keisuke; Sakai, Norisuke

    2007-01-01

    U(Nc) gauge theory with Nf fundamental scalars admits BPS junctions of domain walls. When the networks/webs of these walls contain loops, their size moduli give localized massless modes. We construct K\\"ahler potential of their effective action. In the large size limit K\\"ahler metric is well approximated by kinetic energy of walls and junctions, which is understood in terms of tropical geometry. K\\"ahler potential can be expressed in terms of hypergeometric functions which are useful to understand small size behavior. Even when the loop shrinks, the metric is regular with positive curvature. Moduli space of a single triangle loop has a geometry between a cone and a cigar.

  19. Reengineering observatory operations for the time domain

    CERN Document Server

    Seaman, Robert L; Hessman, Frederic V

    2014-01-01

    Observatories are complex scientific and technical institutions serving diverse users and purposes. Their telescopes, instruments, software, and human resources engage in interwoven workflows over a broad range of timescales. These workflows have been tuned to be responsive to concepts of observatory operations that were applicable when various assets were commissioned, years or decades in the past. The astronomical community is entering an era of rapid change increasingly characterized by large time domain surveys, robotic telescopes and automated infrastructures, and - most significantly - of operating modes and scientific consortia that span our individual facilities, joining them into complex network entities. Observatories must adapt and numerous initiatives are in progress that focus on redesigning individual components out of the astronomical toolkit. New instrumentation is both more capable and more complex than ever, and even simple instruments may have powerful observation scripting capabilities. Re...

  20. Towards Clone Detection in UML Domain Models

    DEFF Research Database (Denmark)

    Störrle, Harald

    2013-01-01

    Code clones (i.e., duplicate fragments of code) have been studied for long, and there is strong evidence that they are a major source of software faults. Anecdotal evidence suggests that this phenomenon occurs similarly in models, suggesting that model clones are as detrimental to model quality as...... they are to code quality. However, programming language code and visual models have significant differences that make it difficult to directly transfer notions and algorithms developed in the code clone arena to model clones. In this article, we develop and propose a definition of the notion of “model...... clone” based on the thorough analysis of practical scenarios. We propose a formal definition of model clones, specify a clone detection algorithm for UML domain models, and implement it prototypically. We investigate different similarity heuristics to be used in the algorithm, and report the performance...

  1. Towards Clone Detection in UML Domain Models

    DEFF Research Database (Denmark)

    Störrle, Harald

    2010-01-01

    Code clones - that is, duplicate fragments of code - have been studied for a long time. There is strong evidence that code clones are a major source of software faults. Anecdotal evidence suggests that this phenomenon is not restricted to code, but occurs in models in a very similar way. So it is...... likely that model clones are as detrimental to model quality as they are to code quality. However, programming language code and visual models also have significant differences so that notions and algorithms developed in the code clone arena cannot be transferred directly to model clones. In this article......, we discuss how model clones arise by analyzing several practical scenarios. We propose a formal definition of models and clones, that allows us to specify a generic clone detection algorithm. Through a thorough analysis of the detail structure of sample UML domain models, recommendations for clone...

  2. Domain specific software architectures: Command and control

    Science.gov (United States)

    Braun, Christine; Hatch, William; Ruegsegger, Theodore; Balzer, Bob; Feather, Martin; Goldman, Neil; Wile, Dave

    1992-01-01

    GTE is the Command and Control contractor for the Domain Specific Software Architectures program. The objective of this program is to develop and demonstrate an architecture-driven, component-based capability for the automated generation of command and control (C2) applications. Such a capability will significantly reduce the cost of C2 applications development and will lead to improved system quality and reliability through the use of proven architectures and components. A major focus of GTE's approach is the automated generation of application components in particular subdomains. Our initial work in this area has concentrated in the message handling subdomain; we have defined and prototyped an approach that can automate one of the most software-intensive parts of C2 systems development. This paper provides an overview of the GTE team's DSSA approach and then presents our work on automated support for message processing.

  3. Wavefield extrapolation in pseudo-depth domain

    KAUST Repository

    Ma, Xuxin

    2012-01-01

    Extrapolating seismic waves in Cartesian coordinate is prone to uneven spatial sampling, because the seismic wavelength tends to grow with depth, as velocity increase. We transform the vertical depth axis to a pseudo one using a velocity weighted mapping, which can effectively mitigate this wavelength variation. We derive acoustic wave equations in this new domain based on the direct transformation of the Laplacian derivatives, which admits solutions that are more accurate and stable than those derived from the kinematic transformation. The anisotropic versions of these equations allow us to isolate the vertical velocity influence and reduce its impact on modeling and imaging. The major benefit of extrapolating wavefields in pseudo-depth space is its near uniform wavelength as opposed to the normally dramatic change of wavelength with the conventional approach. Time wavefield extrapolation on a complex velocity shows some of the features of this approach.

  4. Domain Walls in Extended Lovelock Gravity

    CERN Document Server

    dS, U Camara; Lima, A L Alves; Sotkov, G M

    2012-01-01

    We derive a BPS-like first order system of equations for a family of flat static domain walls (DWs) of dimensionally extended cubic Lovelock Gravity coupled to massive scalar self-interacting matter. The explicit construction of such DWs is achieved by introducing of an appropriate matter superpotential. We further analyse the dependence of the geometric properties of the asymptotically AdSd space-times representing distinct DWs on the shape of the matter potential, on the values of the Lovelock couplings and on the scalar field boundary conditions. Few explicit examples of Lovelock DWs interpolating between AdS-type vacua of different cosmological constants are presented. In five dimensions our method provides interesting solutions of the Myers-Robinson Quasi-topological Gravity in the presence of matter important for the description of the specific renormalization group flows in its holographic dual four-dimensional CFT perturbed by relevant operators.

  5. Papyrus imaging with terahertz time domain spectroscopy

    Science.gov (United States)

    Labaune, J.; Jackson, J. B.; Pagès-Camagna, S.; Duling, I. N.; Menu, M.; Mourou, G. A.

    2010-09-01

    Terahertz time domain spectroscopic imaging (THz-TDSI) is a non-ionizing, non-contact and non-destructive measurement technique that has been recently utilized to study cultural heritage artifacts. We will present this technique and the results of non-contact measurements of papyrus texts, including images of hidden papyri. Inks for modern papyrus specimens were prepared using the historical binder, Arabic gum, and two common pigments used to write ancient texts, carbon black and red ochre. The samples were scanned in reflection at normal incidence with a pulse with a spectral range between 0.1 and 1.5 THz. Temporal analysis of the signals provides the depths of the layers, and their frequency spectra give information about the inks.

  6. Time Domain Response of the ARIANNA Detector

    CERN Document Server

    Barwick, S W; Besson, D Z; Hanson, J C; Klein, S R; Kleinfelder, S A; Piasecki, M; Ratzlaff, K; Reed, C; Roumi, M; Stezelberger, T; Tatar, J; Walker, J; Young, R; Zou, L

    2014-01-01

    The Antarctic Ross Ice Shelf Antenna Neutrino Array (ARIANNA) is a high-energy neutrino detector designed to record the Askaryan electric field signature of cosmogenic neutrino interactions in ice. To understand the inherent radio-frequency (RF) neutrino signature, the time-domain response of the ARIANNA RF receiver must be measured. ARIANNA uses Create CLP5130-2N log-periodic dipole arrays (LPDAs). The associated effective height operator converts incident electric fields to voltage waveforms at the LDPA terminals. The effective height versus time and incident angle was measured, along with the associated response of the ARIANNA RF amplifier. The results are verified by correlating to field measurements in air and ice, using oscilloscopes. Finally, theoretical models for the Askaryan electric field are combined with the detector response to predict the neutrino signature.

  7. Cultural Heritage and the Public Domain

    Directory of Open Access Journals (Sweden)

    Bas Savenije

    2012-09-01

    by providing their resources on the Internet” (Berlin Declaration 2003. Therefore, in the spirit of the Berlin Declaration, the ARL encourages its members’ libraries to grant all non-commercial users “a free, irrevocable, worldwide, right of access to, and a license to copy, use, distribute, transmit and display the work publicly and to make and distribute derivative works, in any digital medium for any responsible purpose, subject to proper attribution of authorship”. And: “If fees are to be assessed for the use of digitised public domain works, those fees should only apply to commercial uses” (ARL Principles July 2010. In our view, cultural heritage institutions should make public domain material digitised with public funding as widely available as possible for access and reuse. The public sector has the primary responsibility to fund digitisation. The involvement of private partners, however, is encouraged by ARL as well as the Comité des Sages. Private funding for digitisation is a complement to the necessary public investment, especially in times of economic crisis, but should not be seen as a substitute for public funding. As we can see from these reports there are a number of arguments in favour of digitisation and also of providing maximum accessibility to the digitised cultural heritage. In this paper we will investigate the legal aspects of digitisation of cultural heritage, especially public domain material. On the basis of these we will make an inventory of policy considerations regarding reuse. Furthermore, we will describe the conclusions the National Library of the Netherlands (hereafter: KB has formulated and the arguments that support these. In this context we will review public-private partnerships and also the policy of the KB. We will conclude with recommendations for cultural heritage institutions concerning a reuse policy for digitised public domain material.

  8. Developing a Domain Model for Relay Circuits

    DEFF Research Database (Denmark)

    Haxthausen, Anne Elisabeth

    2009-01-01

    In this paper we stepwise develop a domain model for relay circuits as used in railway control systems. First we provide an abstract, property-oriented model of networks consisting of components that can be glued together with connectors. This model is strongly inspired by a network model for...... railways madeby Bjørner et.al., however our model is more general: the components can be of any kind and can later be refined to e.g. railway components or circuit components. Then we show how the abstract network model can be refined into an explicit model for relay circuits. The circuit model describes...... defined, checked to be legal, and the reaction to an input can be simulated....

  9. Domain decomposition methods in computational fluid dynamics

    Science.gov (United States)

    Gropp, William D.; Keyes, David E.

    1992-01-01

    The divide-and-conquer paradigm of iterative domain decomposition, or substructuring, has become a practical tool in computational fluid dynamic applications because of its flexibility in accommodating adaptive refinement through locally uniform (or quasi-uniform) grids, its ability to exploit multiple discretizations of the operator equations, and the modular pathway it provides towards parallelism. These features are illustrated on the classic model problem of flow over a backstep using Newton's method as the nonlinear iteration. Multiple discretizations (second-order in the operator and first-order in the preconditioner) and locally uniform mesh refinement pay dividends separately, and they can be combined synergistically. Sample performance results are included from an Intel iPSC/860 hypercube implementation.

  10. Digital Image Watermarking in Transform Domains

    International Nuclear Information System (INIS)

    Fast development of internet and availability of huge digital content make it easy to create, modify and copy digital media such as audio, video and images. This causes a problem for owners of that content and hence a need to copy right protection tool was essential. First, encryption was proposed but it ensures protection during transmission only and once decryption occurred any one can modify the data. at that point watermarking was introduced as a solution to such problem. Watermarking is a process of inserting a low energy signal in to a high energy one so that it doesn't affect the main signal features. A good digital image watermarking technique should satisfy four requirements: 1) Embedding of a watermark should not degrade the host image visual quality (imperceptibility). 2) The embedded watermark should stick to the host image so that it couldn’t be removed by common image processing operation and could be extracted from the attacked watermarked image (robustness). 3) Knowing the embedding and extraction procedures is sufficient but not enough to extract the watermark; extra keys should be needed (security). 4) The watermarking technique should allow embedding and extraction of more than one watermark each independent of the other (capacity). This thesis presents a watermarking scheme that full fill the mentioned four requirements by jointing transform domains with Fractional Fourier Transform Domain (FracFT). More work on cascaded Discrete Wavelet Transform DWT with FracFT was done to develop a joint transform simply called Fractional Wavelet Transform (FWT). The proposed schemes were tested with different image processing attacks to verify its robustness. Finally, the watermarked image is transmitted over simulated MC CDMA channel to prove robustness in real transmission conditions case.

  11. Optimization Testbed Cometboards Extended into Stochastic Domain

    Science.gov (United States)

    Patnaik, Surya N.; Pai, Shantaram S.; Coroneos, Rula M.; Patnaik, Surya N.

    2010-01-01

    COMparative Evaluation Testbed of Optimization and Analysis Routines for the Design of Structures (CometBoards) is a multidisciplinary design optimization software. It was originally developed for deterministic calculation. It has now been extended into the stochastic domain for structural design problems. For deterministic problems, CometBoards is introduced through its subproblem solution strategy as well as the approximation concept in optimization. In the stochastic domain, a design is formulated as a function of the risk or reliability. Optimum solution including the weight of a structure, is also obtained as a function of reliability. Weight versus reliability traced out an inverted-S-shaped graph. The center of the graph corresponded to 50 percent probability of success, or one failure in two samples. A heavy design with weight approaching infinity could be produced for a near-zero rate of failure that corresponded to unity for reliability. Weight can be reduced to a small value for the most failure-prone design with a compromised reliability approaching zero. The stochastic design optimization (SDO) capability for an industrial problem was obtained by combining three codes: MSC/Nastran code was the deterministic analysis tool, fast probabilistic integrator, or the FPI module of the NESSUS software, was the probabilistic calculator, and CometBoards became the optimizer. The SDO capability requires a finite element structural model, a material model, a load model, and a design model. The stochastic optimization concept is illustrated considering an academic example and a real-life airframe component made of metallic and composite materials.

  12. Domain enhanced lookup time accelerated BLAST

    Directory of Open Access Journals (Sweden)

    Boratyn Grzegorz M

    2012-04-01

    Full Text Available Abstract Background BLAST is a commonly-used software package for comparing a query sequence to a database of known sequences; in this study, we focus on protein sequences. Position-specific-iterated BLAST (PSI-BLAST iteratively searches a protein sequence database, using the matches in round i to construct a position-specific score matrix (PSSM for searching the database in round i + 1. Biegert and Söding developed Context-sensitive BLAST (CS-BLAST, which combines information from searching the sequence database with information derived from a library of short protein profiles to achieve better homology detection than PSI-BLAST, which builds its PSSMs from scratch. Results We describe a new method, called domain enhanced lookup time accelerated BLAST (DELTA-BLAST, which searches a database of pre-constructed PSSMs before searching a protein-sequence database, to yield better homology detection. For its PSSMs, DELTA-BLAST employs a subset of NCBI’s Conserved Domain Database (CDD. On a test set derived from ASTRAL, with one round of searching, DELTA-BLAST achieves a ROC5000 of 0.270 vs. 0.116 for CS-BLAST. The performance advantage diminishes in iterated searches, but DELTA-BLAST continues to achieve better ROC scores than CS-BLAST. Conclusions DELTA-BLAST is a useful program for the detection of remote protein homologs. It is available under the “Protein BLAST” link at http://blast.ncbi.nlm.nih.gov. Reviewers This article was reviewed by Arcady Mushegian, Nick V. Grishin, and Frank Eisenhaber.

  13. A Spatial Domain Quantum Watermarking Scheme

    Science.gov (United States)

    Wei, Zhan-Hong; Chen, Xiu-Bo; Xu, Shu-Jiang; Niu, Xin-Xin; Yang, Yi-Xian

    2016-07-01

    This paper presents a spatial domain quantum watermarking scheme. For a quantum watermarking scheme, a feasible quantum circuit is a key to achieve it. This paper gives a feasible quantum circuit for the presented scheme. In order to give the quantum circuit, a new quantum multi-control rotation gate, which can be achieved with quantum basic gates, is designed. With this quantum circuit, our scheme can arbitrarily control the embedding position of watermark images on carrier images with the aid of auxiliary qubits. Besides reversely acting the given quantum circuit, the paper gives another watermark extracting algorithm based on quantum measurements. Moreover, this paper also gives a new quantum image scrambling method and its quantum circuit. Differ from other quantum watermarking schemes, all given quantum circuits can be implemented with basic quantum gates. Moreover, the scheme is a spatial domain watermarking scheme, and is not based on any transform algorithm on quantum images. Meanwhile, it can make sure the watermark be secure even though the watermark has been found. With the given quantum circuit, this paper implements simulation experiments for the presented scheme. The experimental result shows that the scheme does well in the visual quality and the embedding capacity. Supported by the National Natural Science Foundation of China under Grant Nos. 61272514, 61170272, 61373131, 61121061, 61411146001, the program for New Century Excellent Talents under Grant No. NCET-13-0681, the National Development Foundation for Cryptological Research (Grant No. MMJJ201401012) and the Fok Ying Tung Education Foundation under Grant No. 131067, and the Shandong Provincial Natural Science Foundation of China under Grant No. ZR2013FM025

  14. Phase transitions and domain structures in multiferroics

    Science.gov (United States)

    Vlahos, Eftihia

    2011-12-01

    Thin film ferroelectrics and multiferroics are two important classes of materials interesting both from a scientific and a technological prospective. The volatility of lead and bismuth as well as environmental issues regarding the toxicity of lead are two disadvantages of the most commonly used ferroelectric random access memory (FeRAM) materials such as Pb(Zr,Ti)O3 and SrBi2Ta2O9. Therefore lead-free thin film ferroelectrics are promising substitutes as long as (a) they can be grown on technologically important substrates such as silicon, and (b) their T c and Pr become comparable to that of well established ferroelectrics. On the other hand, the development of functional room temperature ferroelectric ferromagnetic multiferroics could lead to very interesting phenomena such as control of magnetism with electric fields and control of electrical polarization with magnetic fields. This thesis focuses on the understanding of material structure-property relations using nonlinear optical spectroscopy. Nonlinear spectroscopy is an excellent tool for probing the onset of ferroelectricity, and domain dynamics in strained ferroelectrics and multiferroics. Second harmonic generation was used to detect ferroelectricity and the antiferrodistortive phase transition in thin film SrTiO3. Incipient ferroelectric CaTiO3 has been shown to become ferroelectric when strained with a combination of SHG and dielectric measurements. The tensorial nature of the induced nonlinear polarization allows for probing of the BaTiO3 and SrTiO3 polarization contributions in nanoscale BaTiO3/SrTiO3 superlattices. In addition, nonlinear optics was used to demonstrate ferroelectricity in multiferroic EuTiO3. Finally, confocal SHG and Raman microscopy were utilized to visualize polar domains in incipient ferroelectric and ferroelastic CaTiO3.

  15. The electrical Lithosphere of the Alboran Domain

    Science.gov (United States)

    Garcia, X. A.; Evans, R. L.; Elsenbeck, J.; Jegen, M. D.; Matsuno, T.

    2011-12-01

    On the Western edge of the Mediterranean, the slow convergence of the Iberian and African plates is marked by very intricate tectonic activity, marked by a combination of small-scale subduction and sub-lithospheric downwelling. Delamination or convective instability has also been proposed to have occurred beneath this domain during the past 25 My. And different geodynamic models have been proposed to explain the lithospheric structure of the arc-shaped belt (Betic and Rif orogenies) and the opening of the Alboran Basin. As part of several international projects carried out in this area, magnetotelluric (MT) methods have been used to explore the crust and upper mantle. The measurements of mantle electrical conductivity are a well known complement to measurements of seismic velocity. Conductivity is sensitive to temperature, composition and hydration of the mantle, and therefore MT is widely used to provide constraints on mantle processes. We present results of electromagnetic studies in the Western Mediterranean, focusing specially in the recently work on the Alboran sea as part of a marine MT survey. Land MT studies have already imaged an area of low resistivity coincident with an area of low velocities without earthquake hypocenters, interpreted as asthenospheric material intruded by the lateral lithospheric tearing and breaking-off of the east-directed subducting Ligurian slab under the Alboran Domain. The model suggests that the most likely scenario for the opening of the Alboran Basin is related to the westward rollback of the Ligurian subducting slab. The marine data show complex MT response functions with strong distortion due to seafloor topography and coast effect, suggesting a fairly resistive lithosphere beneath the seafloor.

  16. Centromere domain organization and histone modifications

    Directory of Open Access Journals (Sweden)

    Bjerling P.

    2002-01-01

    Full Text Available Centromere function requires the proper coordination of several subfunctions, such as kinetochore assembly, sister chromatid cohesion, binding of kinetochore microtubules, orientation of sister kinetochores to opposite spindle poles, and their movement towards the spindle poles. Centromere structure appears to be organized in different, separable domains in order to accomplish these functions. Despite the conserved nature of centromere functions, the molecular genetic definition of the DNA sequences that form a centromere in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe, in the fruit fly Drosophila melanogaster, and in humans has revealed little conservation at the level of centromere DNA sequences. Also at the protein level few centromere proteins are conserved in all of these four organisms and many are unique to the different organisms. The recent analysis of the centromere structure in the yeast S. pombe by electron microscopy and detailed immunofluorescence microscopy of Drosophila centromeres have brought to light striking similarities at the overall structural level between these centromeres and the human centromere. The structural organization of the centromere is generally multilayered with a heterochromatin domain and a central core/inner plate region, which harbors the outer plate structures of the kinetochore. It is becoming increasingly clear that the key factors for assembly and function of the centromere structure are the specialized histones and modified histones which are present in the centromeric heterochromatin and in the chromatin of the central core. Thus, despite the differences in the DNA sequences and the proteins that define a centromere, there is an overall structural similarity between centromeres in evolutionarily diverse eukaryotes.

  17. Spectral/Fourier Domain Optical Coherence Tomography

    Science.gov (United States)

    de Boer, Johannes F.

    Optical coherence tomography is a low-coherence interferometric method for imaging of biological tissue [1, 2]. For more than a decade after its inception between 1988 and 1991, the dominant implementation has been time domain OCT (TD-OCT), in which the length of a reference arm is rapidly scanned. The first spectral or Fourier domain OCT (SD/FD-OCT) implementation was reported in 1995 [3]. In SD-OCT the reference arm is kept stationary, and the depth information is obtained by a Fourier transform of the spectrally resolved interference fringes in the detection arm of a Michelson interferometer. This approach has provided a significant advantage in signal-to-noise ratio (SNR), which despite reports as early as 1997 [4, 5] has taken about half a decade to be recognized fully by the OCT community in 2003 [6-8]. The first demonstration of SD-OCT for in vivo retinal imaging in 2002 [9] was followed by a full realization of the sensitivity advantage by video rate in vivo retinal imaging [10], including high-speed 3-D volumetric imaging [11], ultrahigh-resolution video rate imaging [12, 13], and Doppler blood flow determination in the human retina [14, 15]. The superior sensitivity of SD-OCT, combined with the lack of need for a fast mechanical scanning mechanism, has opened up the possibility of much faster scanning without loss of image quality and provided a paradigm shift from point sampling to volumetric mapping of biological tissue in vivo. The technology has been particularly promising for ophthalmology [16, 17]. In this chapter, the principles and system design considerations of SD-OCT will be discussed in more detail.

  18. Taxonomy for spatial domain LSB steganography techniques

    Science.gov (United States)

    Collins, James C.; Agaian, Sos S.

    2014-05-01

    The Least Significant Bit (LSB) embedding technique is a well-known and broadly employed method in multimedia steganography, used mainly in applications involving single bit-plane manipulations in the spatial domain [1]. The key advantages of LSB procedures are they are simple to understand, easy to implement, have high embedding capacity, and can be resistant to steganalysis attacks. Additionally, the LSB approach has spawned numerous applications and can be used as the basis of more complex techniques for multimedia data embedding. In the last several decades, hundreds of new LSB or LSB variant methods have been developed in an effort to optimize capacity while minimizing detectability, taking advantage of the overall simplicity of this method. LSB-steganalysis research has also intensified in an effort to find new or improved ways to evaluate the performance of this widely used steganographic system. This paper reviews and categorizes some of these major techniques of LSB embedding, focusing specifically on the spatial domain. Some justification for establishing and identifying promising uses of a proposed SD-LSB centric taxonomy are discussed. Specifically, we define a new taxonomy for SD-LSB embedding techniques with the goal of aiding researchers in tool classification methodologies that can lead to advances in the state-of-the-art in steganography. With a common framework to work with, researchers can begin to more concretely identify core tools and common techniques to establish common standards of practice for steganography in general. Finally, we provide a summary on some of the most common LSB embedding techniques followed by a proposed taxonomy standard for steganalysis.

  19. Effectiveness of Usability Attributes in Domains of Virtual Environment

    Directory of Open Access Journals (Sweden)

    Kirti Muley

    2016-05-01

    Full Text Available In recent years, Virtual Environment (VE has gained immense attention of researchers. VE has its applications in all most all domains of software development. At the same time, it is worth to incorporate software usability attributes to develop an effective VE based application. A wide range of usability attributes may be used for different application areas and for environment. Hence, importance of usability attribute also varies from domain to domain or from application to application. In this paper, we attempt to identify the effectiveness of usability attributes specifically, in domains of VE. Algorithm BayesPost is proposed to evaluate the effectiveness of usability attributes of interest in various domains of VE. For execution of the algorithm, we have selected five domains such as Simulation, Educational Websites, Banking Sector, Medical and Entertainment covering 19 usability attributes. On the basis of this study, it may be stated that the probability of existence of usability attribute Interactivity is higher in the domains associated with learning. In contrast, usability attribute Readability possesses lower probability of existence in domains where visual effects are dominant as compared to textual data. It is also observed that probability of existence of usability attribute Active Distraction is subdominant in all domains except medical domain

  20. Energy principle of ferroelectric ceramics and single domain mechanical model

    Institute of Scientific and Technical Information of China (English)

    Feng Liu; Haijun Li; T. C. Wang

    2007-01-01

    Many physical experiments have shown that the domain switching in a ferroelectric material is a complicated evolution process of the domain wall with the variation of stress and electric field. According to this mechanism, the volume fraction of the domain switching is in troduced inthe constitutive law of ferroelectric ceramic and used to study the nonlinear constitutive behavior of ferroelectric body in this paper. The principle of stationary total energy is put forward in which the basic Unknown quantities are the displacement ui, electric displacement Di and volume fraction PI of the domain switching for the variant I. Mechanical fielde quation and a new domain switching criterion are obtained from the principle of stationary total energy. The domains witching criterion proposed in this paper is an expansion and development of the energy criterion. On the basis of the domain switching criterion, a set of linear algebraic equations for the volume fraction pI of domain switching is obtained, in which the coefficients of the linear algebraic equations only contain the unknown strain and electric fields. Then a single domain mechanical model is proposed in this paper. The poled ferroelectric specimen is considered as a transversely isotropic single domain. By using the partial experimental results, the hardening relation between the driving force of domain switching and the volume fraction of domain switching can be calibrated. Then the electromechanical responsecan be calculated on the basis of the calibrated hardening relation. The results involve the electric butterfly shaped curves of axial strain versus axial electric field, the hysteresis loops of electric displacement versus electric filed and the evolution process of the domain switching in the ferroelectric specimens under uniaxial coupled stress and electric field loading. The present theoretic prediction agrees reasonably with the experimental results given by Lynch.

  1. Ballistic rectification of vortex domain wall chirality at nanowire corners

    Energy Technology Data Exchange (ETDEWEB)

    Omari, K.; Bradley, R. C.; Broomhall, T. J.; Hodges, M. P. P.; Hayward, T. J. [Department of Materials Science and Engineering, University of Sheffield, Sheffield S1 3JD (United Kingdom); Rosamond, M. C.; Linfield, E. H. [School of Electronic and Electrical Engineering, University of Leeds, Leeds LS2 9JT (United Kingdom); Im, M.-Y. [Center for X-Ray Optics, Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States); Daegu Gyeongbuk Institute of Science and Technology, Daegu 711-873 (Korea, Republic of); Fischer, P. [Materials Sciences Division, Lawrence Berkley National Laboratory, Berkeley, California 94720 (United States); Department of Physics, University of California, Santa Cruz, California 94056 (United States)

    2015-11-30

    The interactions of vortex domain walls with corners in planar magnetic nanowires are probed using magnetic soft X-ray transmission microscopy. We show that when the domain walls are propagated into sharp corners using applied magnetic fields above a critical value, their chiralities are rectified to either clockwise or anticlockwise circulation depending on whether the corners turn left or right. Single-shot focused magneto-optic Kerr effect measurements are then used to demonstrate how, when combined with modes of domain propagation that conserve vortex chirality, this allows us to dramatically reduce the stochasticity of domain pinning at artificial defect sites. Our results provide a tool for controlling domain wall chirality and pinning behavior both in further experimental studies and in future domain wall-based memory, logic and sensor technologies.

  2. Evolution of spherical domain walls in solitonic symmetron models

    CERN Document Server

    Peyravi, Marzieh; Lobo, Francisco S N

    2016-01-01

    In this work, inspired by the symmetron model, we analyse the evolution of spherical domain walls by considering specific potentials that ensure symmetry breaking and the occurrence of degenerate vacua that are necessary for the formation of domain walls. By considering a simple analytical model of spherical domain wall collapse, in vacuum, it is shown that this model fits the more accurate numerical results very well until full collapse, after which oscillations and scalar radiation take place. Furthermore, we explore the effect of a central non-relativistic matter lump on the evolution of a spherical domain wall and show that the central lump can prevent the full collapse and annihilation of the domain wall bubble, due to the repulsion between the domain wall and matter over-density within the adopted symmetron inspired model.

  3. The transcriptional repressor domain of Gli3 is intrinsically disordered.

    Directory of Open Access Journals (Sweden)

    Robert Tsanev

    Full Text Available The transcription factor Gli3 is acting mainly as a transcriptional repressor in the Sonic hedgehog signal transduction pathway. Gli3 contains a repressor domain in its N-terminus from residue G106 to E236. In this study we have characterized the intracellular structure of the Gli3 repressor domain using a combined bioinformatics and experimental approach. According to our findings the Gli3 repressor domain while being intrinsically disordered contains predicted anchor sites for partner interactions. The obvious interaction partners to test were Ski and DNA; however, with both of these the structure of Gli3 repressor domain remained disordered. To locate residues important for the repressor function we mutated several residues within the Gli3 repressor domain. Two of these, H141A and H157N, targeting predicted helical regions, significantly decreased transcriptional repression and thus identify important functional parts of the domain.

  4. Analysis of acoustic radiation mode in time domain

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The acoustic radiation mode of plane, whose radiating operator is constructed by Rayleigh integral, is investigated in the time domain and its physical meaning is given. The relationship between the acoustic radiation modes of time domain and frequency domain is discussed. It is verified that the acoustic radiation modes are the natural property of the radiator and they can be obtained by different methods. These time domain radiation modes, whose shapes are only dependent on the geometry size and shape of the radiator, can radiate sound power independently. Especially, the first time domain radiation mode accounts for most of the sound radiation. All these simplify the calculation and control of the structure-borne sound power. Based on these observations, the sound power radiated from the vibrating plate is estimated by the time domain radiation mode for verifying the proposed method. The influence factors on the estimating accuracy in different conditions are discussed.

  5. Kinetics of Domains Registration in Multicomponent Lipid Bilayer Membranes

    Science.gov (United States)

    Sornbundit, Kan; Modchang, Charin; Triampo, Wannapong; Triampo, Darapond; Nuttavut, Narin; Sunil Kumar, P.B; Laradji, Mohamed

    2014-01-01

    The kinetics of registration of lipid domains in the apposing leaflets of symmetric bilayer membranes is investigated via systematic dissipative particle dynamics simulations. The decay of the distance between the centres of mass of the domains in the apposing leaflets is almost linear during early stages, and then becomes exponential during late times. The time scales of both linear and exponential decays are found to increase with decreasing the strength of interleaflet coupling. The ratio between the time scales of the exponential and linear regimes decreases with increasing the domain size, implying that the decay of the distance between the domains centres of mass is essentially linear for large domains. These numerical results are largely in agreement with the recent theoretical predictions of Han and Haataja [Soft Matter (2013) 9:2120-2124]. We also found that the domains become elongated during the registration process. PMID:25090030

  6. Mirror Domain Structures Induced by Interlayer Magnetic Wall Coupling

    Science.gov (United States)

    Lew, W. S.; Li, S. P.; Lopez-Diaz, L.; Hatton, D. C.; Bland, J. A.

    2003-05-01

    We have found that during giant magnetoresistance measurements in ˜10×10 mm2 NiFe/Cu/Co continuous film spin-valve structures, the resistance value suddenly drops to its absolute minimum during the NiFe reversal. The results reveal that the alignment of all magnetic domains in the NiFe film follow exactly that of corresponding domains in the Co film for an appropriate applied field strength. This phenomenon is caused by trapping of the NiFe domain walls through the magnetostatic interaction with the Co domain-wall stray fields. Consequently, the interlayer domain-wall coupling induces a mirror domain structure in the magnetic trilayer.

  7. Ballistic rectification of vortex domain wall chirality at nanowire corners

    Science.gov (United States)

    Omari, K.; Bradley, R. C.; Broomhall, T. J.; Hodges, M. P. P.; Rosamond, M. C.; Linfield, E. H.; Im, M.-Y.; Fischer, P.; Hayward, T. J.

    2015-11-01

    The interactions of vortex domain walls with corners in planar magnetic nanowires are probed using magnetic soft X-ray transmission microscopy. We show that when the domain walls are propagated into sharp corners using applied magnetic fields above a critical value, their chiralities are rectified to either clockwise or anticlockwise circulation depending on whether the corners turn left or right. Single-shot focused magneto-optic Kerr effect measurements are then used to demonstrate how, when combined with modes of domain propagation that conserve vortex chirality, this allows us to dramatically reduce the stochasticity of domain pinning at artificial defect sites. Our results provide a tool for controlling domain wall chirality and pinning behavior both in further experimental studies and in future domain wall-based memory, logic and sensor technologies.

  8. Lipid membrane domains in cell surface and vacuolar systems.

    Science.gov (United States)

    Kobayashi, T; Hirabayashi, Y

    2000-01-01

    Detergent insoluble sphingolipid-cholesterol enriched 'raft'-like membrane microdomains have been implicated in a variety of biological processes including sorting, trafficking, and signaling. Mutant cells and knockout animals of sphingolipid biosynthesis are clearly useful to understand the biological roles of lipid components in raft-like domains. It is suggested that raft-like domains distribute in internal vacuolar membranes as well as plasma membranes. In addition to sphingolipid-cholesterol-rich membrane domains, recent studies suggest the existence of another lipid-membrane domain in the endocytic pathway. This domain is enriched with a unique phospholipid, lysobisphosphatidic acid (LBPA) and localized in the internal membrane of multivesicular endosome. LBPA-rich membrane domains are involved in lipid and protein sorting within the endosomal system. Possible interaction between sphingolipids and LBPA in sphingolipid-storage disease is discussed. PMID:11201787

  9. Hepatitis C virus NS4B carboxy terminal domain is a membrane binding domain

    Directory of Open Access Journals (Sweden)

    Spaan Willy JM

    2009-05-01

    Full Text Available Abstract Background Hepatitis C virus (HCV induces membrane rearrangements during replication. All HCV proteins are associated to membranes, pointing out the importance of membranes for HCV. Non structural protein 4B (NS4B has been reported to induce cellular membrane alterations like the membranous web. Four transmembrane segments in the middle of the protein anchor NS4B to membranes. An amphipatic helix at the amino-terminus attaches to membranes as well. The carboxy-terminal domain (CTD of NS4B is highly conserved in Hepaciviruses, though its function remains unknown. Results A cytosolic localization is predicted for the NS4B-CTD. However, using membrane floatation assays and immunofluorescence, we now show targeting of the NS4B-CTD to membranes. Furthermore, a profile-profile search, with an HCV NS4B-CTD multiple sequence alignment, indicates sequence similarity to the membrane binding domain of prokaryotic D-lactate dehydrogenase (d-LDH. The crystal structure of E. coli d-LDH suggests that the region similar to NS4B-CTD is located in the membrane binding domain (MBD of d-LDH, implying analogy in membrane association. Targeting of d-LDH to membranes occurs via electrostatic interactions of positive residues on the outside of the protein with negative head groups of lipids. To verify that anchorage of d-LDH MBD and NS4B-CTD is analogous, NS4B-CTD mutants were designed to disrupt these electrostatic interactions. Membrane association was confirmed by swopping the membrane contacting helix of d-LDH with the corresponding domain of the 4B-CTD. Furthermore, the functionality of these residues was tested in the HCV replicon system. Conclusion Together these data show that NS4B-CTD is associated to membranes, similar to the prokaryotic d-LDH MBD, and is important for replication.

  10. Domains of States of Chemical Systems: Le Chatelier Response, Structure of the Domains and Evolution

    OpenAIRE

    Zilbergleyt, B.

    2005-01-01

    The paper investigates influence of the Le Chatelier response on the chemical system behavior under stress, the shape of its domains of states in terms of static and dynamic bifurcation diagrams, and the system proneness to evolution. The usage of maps in thermodynamics of chemical systems is discussed. Thermodynamics of chemical triggers, designed in similarity with laser, is described. Results of this work are important in context of new model of chemical equilibrium.

  11. Comparison of Functional Protein Transduction Domains Using the NEMO Binding Domain Peptide

    OpenAIRE

    Paul Robbins; Khaleel Khaja

    2010-01-01

    Protein transduction domains (PTDs), both naturally occurring and synthetic, have been extensively utilized for intracellular delivery of biologically active molecules both in vitro and in vivo. However, most comparisons of transduction efficiency have been performed using fluorescent markers. To compare efficiency of functional protein transduction, a peptide derived from IkB kinase ß (IKKß) that prevents formation of an active IKK complex was used as a biologically active cargo. This peptid...

  12. Median Graph Shift: A New Clustering Algorithm for Graph Domain

    OpenAIRE

    Jouili, Salim; Tabbone, Salvatore; Lacroix, Vinciane

    2010-01-01

    n the context of unsupervised clustering, a new algorithm for the domain of graphs is introduced. In this paper, the key idea is to adapt the mean-shift clustering and its variants proposed for the domain of feature vectors to graph clustering. These algorithms have been applied successfully in image analysis and computer vision domains. The proposed algorithm works in an iterative manner by shifting each graph towards the median graph in a neighborhood. Both the set median graph and the gene...

  13. Jensen measures and unbounded B-regular domains in Cn

    International Nuclear Information System (INIS)

    We extend the concept of B-regularity initiated in the class of bounded domains in Cn by Sibony to the class of unbounded domains. The main tool is a duality theorem expressing upper envelopes of functions in terms of lower envelopes of integrals relative to different classes of Jensen measures. We also obtain a global approximation theorem for bounded plurisubharmonic functions on unbounded domains. (author)

  14. Nonlinear analysis of sequence repeats of multi-domain proteins

    International Nuclear Information System (INIS)

    Many multi-domain proteins have repetitive three-dimensional structures but nearly-random amino acid sequences. In the present paper, by using a modified recurrence plot proposed by us previously, we show that these amino acid sequences have hidden repetitions in fact. These results indicate that the repetitive domain structures are encoded by the repetitive sequences. This also gives a method to detect the repetitive domain structures directly from amino acid sequences

  15. Quantitative analysis of magnetic resonance time domain signals

    International Nuclear Information System (INIS)

    A magnetic resonance time domain signal is often made up of a limited number of exponentially decaying sinusoids plus white noise. Traditionally, quantitative analysis of the signal is carried out in the frequency domain, after applying FFT in conjunction with a time window. It is shown that quantitative analysis directly in the time domain is feasible, and in fact yields several advantages. Various methods are applied and compared. (Auth.)

  16. Domain Structures in Nematic Liquid Crystals on a Polycarbonate Surface

    OpenAIRE

    Vasily F. Shabanov; Parshin, Alexander M.; Victor Y. Zyryanov; Gunyakov, Vladimir A.

    2013-01-01

    Alignment of nematic liquid crystals on polycarbonate films obtained with the use of solvents with different solvations is studied. Domain structures occurring during the growth on the polymer surface against the background of the initial thread-like or schlieren texture are demonstrated. It is established by optical methods that the domains are stable formations visualizing the polymer surface structures. In nematic droplets, the temperature-induced transition from the domain structure with ...

  17. Research Perspectives on the Public Domain: Digital Conference Proceedings

    OpenAIRE

    Erickson, Kris; Kretschmer, Martin

    2014-01-01

    The public domain is a subject of vital interest to legal scholars, but its implications are far reaching – indeed, the public domain concept is germane to subjects as diverse as film and media studies, economics, political science and organisational theory. It was a central purpose of the workshop to arrive at a workable definition of the public domain suitable for empirical investigation. The traditional definition (1) takes the copyright term as the starting point, and defines the public d...

  18. The Consequences of Chronic Stereotype Threat: Domain Disidentification and Abandonment

    OpenAIRE

    Woodcock, Anna; Hernandez, Paul R.; Estrada, Mica; Schultz, P. Wesley

    2012-01-01

    Stereotype threat impairs performance across many domains. Despite a wealth of research, the long-term consequences of chronic stereotype threat have received little empirical attention. Beyond the immediate impact on performance, the experience of chronic stereotype threat is hypothesized to lead to domain disidentification and eventual domain abandonment. Stereotype threat is 1 explanation why African Americans and Hispanic/Latino(a)s “leak” from each juncture of the academic scientific pip...

  19. K-groups of Toeplitz algebras on connected domains

    Institute of Scientific and Technical Information of China (English)

    Guang-fu CAO; Xiao-hong WANG

    2007-01-01

    In the present paper, it is proved that the K0-group of a Toeplitz algebra on any connected domain is always isomorphic to the K0-group of the relative continuous function algebra. In addition,the cohomotopy groups of essential boundaries of some connected domains are computed, and the K0-groups of the continuous function algebras on these domains are also computed.

  20. Bias-Driven Revision of Logical Domain Theories

    OpenAIRE

    Koppel, M.; Feldman, R; Segre, A. M.

    1994-01-01

    The theory revision problem is the problem of how best to go about revising a deficient domain theory using information contained in examples that expose inaccuracies. In this paper we present our approach to the theory revision problem for propositional domain theories. The approach described here, called PTR, uses probabilities associated with domain theory elements to numerically track the ``flow'' of proof through the theory. This allows us to measure the precise role of a clause or liter...

  1. Domain Wall Mobility in Co-Based Amorphous Wire

    Directory of Open Access Journals (Sweden)

    Maria Kladivova

    2007-01-01

    Full Text Available Dynamics of the domain wall between opposite circularly magnetized domains in amorphous cylindrical sample with circular easy direction is theoretically studied. The wall is driven by DC current. Various mechanisms which influence the wall velocity were taken into account: current magnitude, deformation of the mowing wall, Hall effect, axially magnetized domain in the middle of the wire. Theoretical results obtained are in a good agreement with experiments on Cobased amorphous ferromagnetic wires.

  2. DOMAC: an accurate, hybrid protein domain prediction server

    OpenAIRE

    Cheng, Jianlin

    2007-01-01

    Protein domain prediction is important for protein structure prediction, structure determination, function annotation, mutagenesis analysis and protein engineering. Here we describe an accurate protein domain prediction server (DOMAC) combining both template-based and ab initio methods. The preliminary version of the server was ranked among the top domain prediction servers in the seventh edition of Critical Assessment of Techniques for Protein Structure Prediction (CASP7), 2006. DOMAC server...

  3. Graphene growth with giant domains using chemical vapor deposition

    OpenAIRE

    Yong, Virginia; Hahn, H. Thomas

    2011-01-01

    We report the first demonstration of the growth of giant graphene domains on platinum (Pt), which results in a uniform bilayer graphene film with domain sizes of millimetre scale. These giant graphene domains are attributed to the giant Pt grains attained in post-deposition annealed Pt thin films that exhibit a strong dependency on the Pt film thickness. Giant grains have been claimed to occur in other metallic materials under appropriate film thicknesses and processing conditions. Our findin...

  4. Social Welfare Functionals on Restricted Domains and in Economic Environments

    OpenAIRE

    Georges Bordes; Hammond, Peter J.; Michel Le Breton

    1997-01-01

    March 1997 Arrow's ``impossibility'' and similar classical theorems are usually proved for an unrestricted domain of preference profiles. Recent work extends Arrow's theorem to various restricted but ``saturating'' domains of privately oriented, continuous, (strictly) convex, and (strictly) monotone ``economic preferences'' for private and/or public goods. For strongly saturating domains of more general utility profiles, this paper provides similar extensions of Wilson's theorem and of the st...

  5. Allosteric Switching by Mutually Exclusive Folding of Protein Domains

    OpenAIRE

    Radley, Tracy L.; Markowska, Anna I.; Bettinger, Blaine T.; Ha, Jeung-Hoi; Loh, Stewart N.

    2003-01-01

    Many proteins are built from structurally and functionally distinct and domains. A major goal is to understand how conformational change transmits information between domains in order to achieve biological activity. A two-domain, bi-functional fusion protein has been designed so that the mechanical stress imposed by the folded structure of one subunit causes the other subunit to unfold, and vice versa. The construct consists of ubiquitin inserted into a surface loop of barnase. The distance b...

  6. Linked-data based domain-specific sentiment lexicons

    OpenAIRE

    Vulcu, Gabriela; Lario Monje, Raúl; Muñoz, Mario; Buitelaar, Paul; Iglesias Fernandez, Carlos Angel

    2014-01-01

    In this paper we present a dataset componsed of domain-specific sentiment lexicons in six languages for two domains. We used existing collections of reviews from Trip Advisor, Amazon, the Stanford Network Analysis Project and the OpinRank Review Dataset. We use an RDF model based on the lemon and Marl formats to represent the lexicons. We describe the methodology that we applied to generate the domain-specific lexicons and we provide access information to our datasets.

  7. Computational Methods for Domain Partitioning of Protein Structures

    Science.gov (United States)

    Veretnik, Stella; Shindyalov, Ilya

    Analysis of protein structures typically begins with decomposition of structure into more basic units, called "structural domains". The underlying goal is to reduce a complex protein structure to a set of simpler yet structurally meaningful units, each of which can be analyzed independently. Structural semi-independence of domains is their hallmark: domains often have compact structure and can fold or function independently. Domains can undergo so-called "domain shuffling"when they reappear in different combinations in different proteins thus implementing different biological functions (Doolittle, 1995). Proteins can then be conceived as being built of such basic blocks: some, especially small proteins, consist usually of just one domain, while other proteins possess a more complex architecture containing multiple domains. Therefore, the methods for partitioning a structure into domains are of critical importance: their outcome defines the set of basic units upon which structural classifications are built and evolutionary analysis is performed. This is especially true nowadays in the era of structural genomics. Today there are many methods that decompose the structure into domains: some of them are manual (i.e., based on human judgment), others are semiautomatic, and still others are completely automatic (based on algorithms implemented as software). Overall there is a high level of consistency and robustness in the process of partitioning a structure into domains (for ˜80% of proteins); at least for structures where domain location is obvious. The picture is less bright when we consider proteins with more complex architectures—neither human experts nor computational methods can reach consistent partitioning in many such cases. This is a rather accurate reflection of biological phenomena in general since domains are formed by different mechanisms, hence it is nearly impossible to come up with a set of well-defined rules that captures all of the observed cases.

  8. The capping domain in RalF regulates effector functions.

    Directory of Open Access Journals (Sweden)

    Eric Alix

    Full Text Available The Legionella pneumophila effector protein RalF functions as a guanine nucleotide exchange factor (GEF that activates the host small GTPase protein ADP-ribosylation factor (Arf, and recruits this host protein to the vacuoles in which this pathogen resides. GEF activity is conferred by the Sec7 domain located in the N-terminal region of RalF. Structural studies indicate that the C-terminal region of RalF makes contacts with residues in the Sec7 domain important for Arf interactions. Theoretically, the C-terminal region of RalF could prevent nucleotide exchange activity by blocking the ability of Arf to interact with the Sec7 domain. For this reason, the C-terminal region of RalF has been termed a capping domain. Here, the role of the RalF capping domain was investigated by comparing biochemical and effector activities mediated by this domain in both the Legionella RalF protein (LpRalF and in a RalF ortholog isolated from the unrelated intracellular pathogen Rickettsia prowazekii (RpRalF. These data indicate that both RalF proteins contain a functional Sec7 domain and that the capping domain regulates RalF GEF activity. The capping domain has intrinsic determinants that mediate localization of the RalF protein inside of host cells and confer distinct effector activities. Localization mediated by the capping domain of LpRalF enables the GEF to modulate membrane transport in the secretory pathway, whereas, the capping domain of RpRalF enables this bacterial GEF to modulate actin dynamics occurring near the plasma membrane. Thus, these data reveal that divergence in the function of the C-terminal capping domain alters the in vivo functions of the RalF proteins.

  9. Addressing Limited Data for Textual Entailment Across Domains

    OpenAIRE

    Shivade, Chaitanya; Raghavan, Preethi; Patwardhan, Siddharth

    2016-01-01

    We seek to address the lack of labeled data (and high cost of annotation) for textual entailment in some domains. To that end, we first create (for experimental purposes) an entailment dataset for the clinical domain, and a highly competitive supervised entailment system, ENT, that is effective (out of the box) on two domains. We then explore self-training and active learning strategies to address the lack of labeled data. With self-training, we successfully exploit unlabeled data to improve ...

  10. Domain Specific Software Architecture for Design Center Automation

    OpenAIRE

    Sinha, Anshuman; Nandela, Haritha; Balakrishna, Vijaya

    2008-01-01

    Domain specific software architecture aims at software reuse through construction of domain architecture reference model. The constructed reference model presents a set of individual components and their interaction points. When starting on a new large software project, the design engineer starts with pre-constructed model, which can be easily browsed and picks up opportunities of use in the new solution design. This report discusses application of domain reference design methods by deriving ...

  11. A Survey on Domain-Specific Languages in Robotics

    OpenAIRE

    Nordmann, Arne; Hochgeschwender, Nico; Wrede, Sebastian

    2014-01-01

    The design, simulation and programming of robotics systems is challenging as expertise from multiple domains needs to be integrated conceptually and technically. Domain-specific modeling promises an efficient and flexible concept for developing robotics applications that copes with this challenge. It allows to raise the level of abstraction through the use of specific concepts that are closer to the respective domain concerns and easier to understand and validate. Furthermore, it focuses on i...

  12. OntoAna: Domain Ontology for Human Anatomy

    OpenAIRE

    Vashisth, Archana; Mathur, Iti; Joshi, Nisheeth

    2012-01-01

    Today, we can find many search engines which provide us with information which is more operational in nature. None of the search engines provide domain specific information. This becomes very troublesome to a novice user who wishes to have information in a particular domain. In this paper, we have developed an ontology which can be used by a domain specific search engine. We have developed an ontology on human anatomy, which captures information regarding cardiovascular system, digestive syst...

  13. Mechanisms for Automated Negotiation in State Oriented Domains

    OpenAIRE

    Zlotkin, G.; Rosenschein, J. S.

    1996-01-01

    This paper lays part of the groundwork for a domain theory of negotiation, that is, a way of classifying interactions so that it is clear, given a domain, which negotiation mechanisms and strategies are appropriate. We define State Oriented Domains, a general category of interaction. Necessary and sufficient conditions for cooperation are outlined. We use the notion of worth in an altered definition of utility, thus enabling agreements in a wider class of joint-goal reachable situations. An a...

  14. On time-domain and frequency-domain MMSE-based TEQ design for DMT transmission

    CERN Document Server

    Vanbleu, K; Moonen, M; Ysebaert, G; 10.1109/TSP.2005.851161

    2005-01-01

    We reconsider the minimum mean square error (MMSE) time-domain equalizer (TEQ), bitrate maximizing TEQ (BM-TEQ), and per-tone equalizer design (PTEQ) for discrete multitone (DMT) transmission and cast them in a common least-squares (LS) based framework. The MMSE- TEQ design criterion can be formulated as a constrained linear least-squares (CLLS) criterion that minimizes a time-domain (TD) error energy. From this CLLS-based TD-MMSE-TEQ criterion, we derive two new least-squares (LS) based frequency-domain (FD) MMSE-TEQ design criteria: a CLLS-based FD-MMSE-TEQ criterion and a so-called separable nonlinear LS (SNLLS) based FD-MMSE-TEQ design. Finally, the original BM-TEQ design is shown to be equivalent to a so-called iteratively-reweighted (IR) version of the SNLLS-based FD-MMSE-TEQ design. This LS-based framework then results in the following contributions. The new, IR-SNLLS-based BM-TEQ design criterion gives rise to an elegant, iterative, fast converging, Gauss-Newton-based design algorithm that exploits th...

  15. Particle Communication and Domain Neighbor Coupling: Scalable Domain Decomposed Algorithms for Monte Carlo Particle Transport

    Energy Technology Data Exchange (ETDEWEB)

    O' Brien, M. J.; Brantley, P. S.

    2015-01-20

    In order to run Monte Carlo particle transport calculations on new supercomputers with hundreds of thousands or millions of processors, care must be taken to implement scalable algorithms. This means that the algorithms must continue to perform well as the processor count increases. In this paper, we examine the scalability of:(1) globally resolving the particle locations on the correct processor, (2) deciding that particle streaming communication has finished, and (3) efficiently coupling neighbor domains together with different replication levels. We have run domain decomposed Monte Carlo particle transport on up to 221 = 2,097,152 MPI processes on the IBM BG/Q Sequoia supercomputer and observed scalable results that agree with our theoretical predictions. These calculations were carefully constructed to have the same amount of work on every processor, i.e. the calculation is already load balanced. We also examine load imbalanced calculations where each domain’s replication level is proportional to its particle workload. In this case we show how to efficiently couple together adjacent domains to maintain within workgroup load balance and minimize memory usage.

  16. Domain topology and domain switching kinetics in a hybrid improper ferroelectric.

    Science.gov (United States)

    Huang, F-T; Xue, F; Gao, B; Wang, L H; Luo, X; Cai, W; Lu, X-Z; Rondinelli, J M; Chen, L Q; Cheong, S-W

    2016-01-01

    Charged polar interfaces such as charged ferroelectric walls or heterostructured interfaces of ZnO/(Zn,Mg)O and LaAlO3/SrTiO3, across which the normal component of electric polarization changes suddenly, can host large two-dimensional conduction. Charged ferroelectric walls, which are energetically unfavourable in general, were found to be mysteriously abundant in hybrid improper ferroelectric (Ca,Sr)3Ti2O7 crystals. From the exploration of antiphase boundaries in bilayer-perovskites, here we discover that each of four polarization-direction states is degenerate with two antiphase domains, and these eight structural variants form a Z4 × Z2 domain structure with Z3 vortices and five distinct types of domain walls, whose topology is directly relevant to the presence of abundant charged walls. We also discover a zipper-like nature of antiphase boundaries, which are the reversible creation/annihilation centres of pairs of two types of ferroelectric walls (and also Z3-vortex pairs) in 90° and 180° polarization switching. Our results demonstrate the unexpectedly rich nature of hybrid improper ferroelectricity. PMID:27215944

  17. Structural domains of vault proteins: a role for the coiled coil domain in vault assembly.

    Science.gov (United States)

    van Zon, Arend; Mossink, Marieke H; Schoester, Martijn; Scheffer, George L; Scheper, Rik J; Sonneveld, Pieter; Wiemer, Erik A C

    2002-03-01

    Vaults consist of multiple copies of three proteins (MVP, VPARP, and TEP1) and several untranslated RNAs. The function of vaults is unknown but the typical and evolutionary conserved structure indicates a role in intracellular transport. Although all vault components have been identified and characterized, not much is known about vault protein assembly. In this study we identified and analyzed structural domains involved in vault assembly with emphasis on protein-protein interactions. Using a yeast two-hybrid system, we demonstrate within MVP an intramolecular binding site and show that MVP molecules interact with each other via their coiled coil domain. We show that purified MVP is able to bind calcium, most likely at calcium-binding EF-hands. No interactions could be detected between TEP1 and other vault proteins. However, the N-terminal half of MVP binds to a specific domain in the C-terminus of VPARP. Furthermore, VPARP contains amino acid stretches mediating intramolecular binding. PMID:11855821

  18. The pedigree of ferroic domains investigations in Japan

    International Nuclear Information System (INIS)

    A part of history of the investigations in the field of ferroic domains done in Japan is reviewed, with emphases placed on activities in academia. Three topics, i.e., polarizing microscopic observations of domains, modeling of the domain walls and polarization reversals, are chosen. Observation of domains in Rochelle salt by Mitsui proved the usefulness of a polarizing microscope. The application by Ishibashi and Takagi of the Kolmogorov-Avrami model to polarization reversals in ferroelectrics has offered a very useful tool in analyzing the switching current in spite of (or because of) its simplicity

  19. Hamilton-Jacobi method for curved domain walls and cosmologies

    Science.gov (United States)

    Skenderis, Kostas; Townsend, Paul K.

    2006-12-01

    We use Hamiltonian methods to study curved domain walls and cosmologies. This leads naturally to first-order equations for all domain walls and cosmologies foliated by slices of maximal symmetry. For Minkowski and AdS-sliced domain walls (flat and closed FLRW cosmologies) we recover a recent result concerning their (pseudo)supersymmetry. We show how domain-wall stability is consistent with the instability of AdS vacua that violate the Breitenlohner-Freedman bound. We also explore the relationship to Hamilton-Jacobi theory and compute the wave-function of a 3-dimensional closed universe evolving towards de Sitter spacetime.

  20. Hamilton-Jacobi for Domain Walls and Cosmologies

    CERN Document Server

    Skenderis, K; Skenderis, Kostas; Townsend, Paul K.

    2006-01-01

    We use Hamiltonian methods to study curved domain walls and cosmologies. This leads naturally to first order equations for all domain walls and cosmologies foliated by slices of maximal symmetry. For Minkowski and AdS-sliced domain walls (flat and closed FLRW cosmologies) we recover a recent result concerning their (pseudo)supersymmetry. We show how domain-wall stability is consistent with the instability of adS vacua that violate the Breitenlohner-Freedman bound. We also explore the relationship to Hamilton-Jacobi theory and compute the wave-function of a 3-dimensional closed universe evolving towards de Sitter spacetime.