WorldWideScience

Sample records for ame teeb liinilennukitele

  1. Jah, internet teeb vabaks / Martin Kala

    Index Scriptorium Estoniae

    Kala, Martin, 1977-

    2011-01-01

    Interneti- ja ajakirjandusvabadusest, sotsiaalmeedia tähtsusest ühiskonnas. Autori hinnagul on Facebookis, blogisfääris ja netisaitidel leviv teave vaid lisandiks traditsioonilisele vabale ja vastutustundlikule meediale. Vastukaja: Meikar, Silver. Kas Internet ikka teeb vabaks?// Postimees : AK : arvamus, kultuur (2011) 23. apr., lk. 2-3

  2. Autonomy @ Ames

    Science.gov (United States)

    Van Dalsem, William; Krishnakumar, Kalmanje Srinivas

    2016-01-01

    This is a powerpoint presentation that highlights autonomy across the 15 NASA technology roadmaps, including specific examples of projects (past and present) at NASA Ames Research Center. The NASA technology roadmaps are located here: http:www.nasa.govofficesocthomeroadmapsindex.html

  3. VP Market teeb rekordkasvu / Ralf-Martin Soe

    Index Scriptorium Estoniae

    Soe, Ralf-Martin

    2006-01-01

    Ilmunud ka: Delovõje Vedomosti 26. apr. lk. 4. Leedu omanikele kuuluv T-Marketite poekett teeb Eestis rekordilist käibe kasvu. Diagramm. Vt. samas: Raimo Ülavere. VP Market annab konkurentidele silmad ette

  4. Ehitus Service teeb silma Ukraina miljonilinnadele / Anne Oja

    Index Scriptorium Estoniae

    Oja, Anne, 1970-

    2007-01-01

    Ehitus Service teeb ettevalmistusi sisenemiseks Ukraina turule. Diagramm: Eesti otseinvesteeringud Ukrainasse; Ehitus Service majandusnäitajad ja omanikud. Vt. samas: Askembla: plaanid on veel lahtised; Konkurent peab Ukrainat põnevaks

  5. YLE TV teeb koos Oksasega KGB-filmi

    Index Scriptorium Estoniae

    2011-01-01

    Sofi Oksanen külastas koos YLE TV võttegrupiga Tallinna Ülikooli Akadeemilist Raamatukogu. YLE teeb filmi Eesti NSV KGB tegevusest ja vastupropagandast. Väliseesti kirjanduse keskuse juhataja Anne Valmas rääkis raamatukogu kinnise osakonna ja selle propagandisti Andrus Roolahe tegevusest

  6. Routine environmental audit of Ames Laboratory, Ames, Iowa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-09-01

    This document contains the findings identified during the routine environmental audit of Ames Laboratory, Ames, Iowa, conducted September 12--23, 1994. The audit included a review of all Ames Laboratory operations and facilities supporting DOE-sponsored activities. The audit`s objective is to advise the Secretary of Energy, through the Assistant Secretary for Environment, Safety and Health, as to the adequacy of the environmental protection programs established at Ames Laboratory to ensure the protection of the environment, and compliance with Federal, state, and DOE requirements.

  7. Routine environmental audit of Ames Laboratory, Ames, Iowa

    International Nuclear Information System (INIS)

    1994-09-01

    This document contains the findings identified during the routine environmental audit of Ames Laboratory, Ames, Iowa, conducted September 12--23, 1994. The audit included a review of all Ames Laboratory operations and facilities supporting DOE-sponsored activities. The audit's objective is to advise the Secretary of Energy, through the Assistant Secretary for Environment, Safety and Health, as to the adequacy of the environmental protection programs established at Ames Laboratory to ensure the protection of the environment, and compliance with Federal, state, and DOE requirements

  8. Teater teeb töötutele menuetenduse välja / Aarne Mäe

    Index Scriptorium Estoniae

    Mäe, Aarne, 1967-

    2005-01-01

    Fr. Echrenbuschì "Täismäng" Rakvere teatri külalisetendusena Tallinnas Salme kultuurikeskuses, lavastaja I. Vihmar. Sel puhul teeb teater koos tööhõiveametiga 50 töötule ja nende kaaslastele välja etenduse piletid

  9. Eesti teeb koos soomlaste ja hiinlastega kung-fu filmi / Mari Rebane

    Index Scriptorium Estoniae

    Rebane, Mari

    2005-01-01

    Soome ja Hiina mütoloogiat ühendava fantaasiafilmi "Armuvalus sõdalane" (eelarve 39 milj. krooni) tootjad on Soome, Holland, Hiina ja Eesti (3,9 milj. krooni). Kaasa teeb ka Elle Kull, lavastab debütant AJ Annila

  10. "TEEB begins now": a virtual moment in the production of natural capital.

    Science.gov (United States)

    MacDonald, Kenneth Iain; Corson, Catherine

    2012-01-01

    This article uses theories of virtualism to analyse the role of The Economics of Ecosystems and Biodiversity (TEEB) project in the production of natural capital. Presented at the 10th Conference of the Parties to the Convention on Biological Diversity, the project seeks to redress the ‘economic invisibility of nature’ by quantifying the value of ecosystems and biodiversity. This endeavour to put an economic value on ecosystems makes nature legible by abstracting it from social and ecological contexts and making it subject to, and productive of, new market devices. In reducing the complexity of ecological dynamics to idealized categories TEEB is driven by economic ideas and idealism, and, in claiming to be a quantitative force for morality, is engaged in the production of practices designed to conform the ‘real’ to the virtual. By rendering a ‘valued’ nature legible for key audiences, TEEB has mobilized a critical mass of support including modellers, policy makers and bankers. We argue that TEEB's rhetoric of crisis and value aligns capitalism with a new kind of ecological modernization in which ‘the market’ and market devices serve as key mechanisms to conform the real and the virtual. Using the case of TEEB, and drawing on data collected at COP10, we illustrate the importance of international meetings as key points where idealized models of biodiversity protection emerge, circulate and are negotiated, and as sites where actors are aligned and articulated with these idealized models in ways that begin further processes of conforming the real with the virtual and the realization of ‘natural capital’.

  11. Vootele Vaher enne teeb ja siis mõtleb / Vootele Vaher ; küsitles Tiiu Laks

    Index Scriptorium Estoniae

    Vaher, Vootele

    2007-01-01

    Vootele Vaher on töötanud aastaid Lõuna-Euroopa professionaalsetes rändtsirkustes, on lõpetamas Tallinna Ülikoolis koreograafia eriala, teeb tantsuetendusi. Tema diplomitööst "Circo barabellum"

  12. Ames Optimized TCA Configuration

    Science.gov (United States)

    Cliff, Susan E.; Reuther, James J.; Hicks, Raymond M.

    1999-01-01

    Configuration design at Ames was carried out with the SYN87-SB (single block) Euler code using a 193 x 49 x 65 C-H grid. The Euler solver is coupled to the constrained (NPSOL) and the unconstrained (QNMDIF) optimization packages. Since the single block grid is able to model only wing-body configurations, the nacelle/diverter effects were included in the optimization process by SYN87's option to superimpose the nacelle/diverter interference pressures on the wing. These interference pressures were calculated using the AIRPLANE code. AIRPLANE is an Euler solver that uses a unstructured tetrahedral mesh and is capable of computations about arbitrary complete configurations. In addition, the buoyancy effects of the nacelle/diverters were also included in the design process by imposing the pressure field obtained during the design process onto the triangulated surfaces of the nacelle/diverter mesh generated by AIRPLANE. The interference pressures and nacelle buoyancy effects are added to the final forces after each flow field calculation. Full details of the (recently enhanced) ghost nacelle capability are given in a related talk. The pseudo nacelle corrections were greatly improved during this design cycle. During the Ref H and Cycle 1 design activities, the nacelles were only translated and pitched. In the cycle 2 design effort the nacelles can translate vertically, and pitch to accommodate the changes in the lower surface geometry. The diverter heights (between their leading and trailing edges) were modified during design as the shape of the lower wing changed, with the drag of the diverter changing accordingly. Both adjoint and finite difference gradients were used during optimization. The adjoint-based gradients were found to give good direction in the design space for configurations near the starting point, but as the design approached a minimum, the finite difference gradients were found to be more accurate. Use of finite difference gradients was limited by the

  13. Environmental Survey preliminary report, Ames Laboratory, Ames, Iowa

    Energy Technology Data Exchange (ETDEWEB)

    1989-03-01

    This report presents the preliminary findings of the first phase of the environmental Survey of the United States Department of Energy's (DOE) Ames Laboratory, conducted April 18 through 22, 1988. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team members are being supplied by private contractors. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with the Ames Laboratory. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at the Ames Laboratory, and interviews with site personnel. The Survey team developed a Sampling and Analysis (S A) Plan to assist in further assessing certain of the environmental problems identified during its on-site activities. The S A plan is being developed by the Idaho National Engineering Laboratory. When S A is completed, the results will be incorporated into the Ames Laboratory Environmental Survey findings for inclusion in the Environmental Survey Summary Report. 60 refs., 13 figs., 20 tabs.

  14. NASA Ames Environmental Sustainability Report 2011

    Science.gov (United States)

    Clarke, Ann H.

    2011-01-01

    The 2011 Ames Environmental Sustainability Report is the second in a series of reports describing the steps NASA Ames Research Center has taken toward assuring environmental sustainability in NASA Ames programs, projects, and activities. The Report highlights Center contributions toward meeting the Agency-wide goals under the 2011 NASA Strategic Sustainability Performance Program.

  15. Management process invaded Ames as the Center shifted from NACA to NASA oversight. Ames constructed

    Science.gov (United States)

    1968-01-01

    Management process invaded Ames as the Center shifted from NACA to NASA oversight. Ames constructed a review room in its headquarters building where, in the graphical style that prevailed in the 1960's, Ames leadership could review progress against schedule, budget and performance measures. Shown, in October 1965 is Merrill Mead chief of Ames' program and resources office. (for H Julian Allen Retirement album)

  16. NASA-Ames vertical gun

    Science.gov (United States)

    Schultz, P. H.

    1984-01-01

    A national facility, the NASA-Ames vertical gun range (AVGR) has an excellent reputation for revealing fundamental aspects of impact cratering that provide important constraints for planetary processes. The current logistics in accessing the AVGR, some of the past and ongoing experimental programs and their relevance, and the future role of this facility in planetary studies are reviewed. Publications resulting from experiments with the gun (1979 to 1984) are listed as well as the researchers and subjects studied.

  17. Ames Life Science Data Archive: Translational Rodent Research at Ames

    Science.gov (United States)

    Wood, Alan E.; French, Alison J.; Ngaotheppitak, Ratana; Leung, Dorothy M.; Vargas, Roxana S.; Maese, Chris; Stewart, Helen

    2014-01-01

    The Life Science Data Archive (LSDA) office at Ames is responsible for collecting, curating, distributing and maintaining information pertaining to animal and plant experiments conducted in low earth orbit aboard various space vehicles from 1965 to present. The LSDA will soon be archiving data and tissues samples collected on the next generation of commercial vehicles; e.g., SpaceX & Cygnus Commercial Cargo Craft. To date over 375 rodent flight experiments with translational application have been archived by the Ames LSDA office. This knowledge base of fundamental research can be used to understand mechanisms that affect higher organisms in microgravity and help define additional research whose results could lead the way to closing gaps identified by the Human Research Program (HRP). This poster will highlight Ames contribution to the existing knowledge base and how the LSDA can be a resource to help answer the questions surrounding human health in long duration space exploration. In addition, it will illustrate how this body of knowledge was utilized to further our understanding of how space flight affects the human system and the ability to develop countermeasures that negate the deleterious effects of space flight. The Ames Life Sciences Data Archive (ALSDA) includes current descriptions of over 700 experiments conducted aboard the Shuttle, International Space Station (ISS), NASA/MIR, Bion/Cosmos, Gemini, Biosatellites, Apollo, Skylab, Russian Foton, and ground bed rest studies. Research areas cover Behavior and Performance, Bone and Calcium Physiology, Cardiovascular Physiology, Cell and Molecular Biology, Chronobiology, Developmental Biology, Endocrinology, Environmental Monitoring, Gastrointestinal Physiology, Hematology, Immunology, Life Support System, Metabolism and Nutrition, Microbiology, Muscle Physiology, Neurophysiology, Pharmacology, Plant Biology, Pulmonary Physiology, Radiation Biology, Renal, Fluid and Electrolyte Physiology, and Toxicology. These

  18. Economic tools for biodiversity. An elaboration of TEEB recommendations with regard to the Taskforce Biodiversity

    International Nuclear Information System (INIS)

    Davidson, M.D.; Bergsma, G.C.; Blom, M.J.

    2011-07-01

    The working group on Economic Instruments of the Biodiversity and Natural Resources Task Force addressed the question how the recommendations of the report of the United Nations 'The Economics of Ecosystems and Biodiversity' (TEEB) can be realized in the Netherlands. A selection of topics has been made for which policy proposals are developed which might be promising and can lead to a better protection of the biodiversity. The following proposals were investigated and/or elaborated: decrease of the social discount rate; further greening of the tax system; import levy on bulk commodities; taxes on non-sustainable wood; levy on the use of open space; differential tax on animal proteins; and a revision of biomass incentives. [nl

  19. Tiger Team Assessment of the Ames Laboratory

    International Nuclear Information System (INIS)

    1992-03-01

    This report documents the Tiger Assessment of the Ames Laboratory (Ames), located in Ames, Iowa. Ames is operated for the US Department of Energy (DOE) by Iowa State University. The assessment was conducted from February 10 to March 5, 1992, under the auspices of the Office of Special Projects, Office of the Assistant Secretary of Environment, Safety and Health, Headquarters, DOE. The assessment was comprehensive, encompassing Environment, Safety, and Health (ES ampersand H) disciplines; management practices; and contractor and DOE self-assessments. Compliance with applicable Federal, State of Iowa, and local regulations; applicable DOE Orders; best management practices; and internal requirements at Ames Laboratory were assessed. In addition, an evaluation of the adequacy and effectiveness of DOE and the site contractor's management of ES ampersand H/quality assurance program was conducted

  20. Tiger Team Assessment of the Ames Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1992-03-01

    This report documents the Tiger Assessment of the Ames Laboratory (Ames), located in Ames, Iowa. Ames is operated for the US Department of Energy (DOE) by Iowa State University. The assessment was conducted from February 10 to March 5, 1992, under the auspices of the Office of Special Projects, Office of the Assistant Secretary of Environment, Safety and Health, Headquarters, DOE. The assessment was comprehensive, encompassing Environment, Safety, and Health (ES H) disciplines; management practices; and contractor and DOE self-assessments. Compliance with applicable Federal, State of Iowa, and local regulations; applicable DOE Orders; best management practices; and internal requirements at Ames Laboratory were assessed. In addition, an evaluation of the adequacy and effectiveness of DOE and the site contractor's management of ES H/quality assurance program was conducted.

  1. Photographer: NASA Ames On 20 December 1989, Ames buried a time capsule and unveiled a sculpture at

    Science.gov (United States)

    1989-01-01

    Photographer: NASA Ames On 20 December 1989, Ames buried a time capsule and unveiled a sculpture at the spot where, fifty years earlier, Russel Robinson had turned the first spade of dirt for the Ames construction shack: Robinson (left) Ames Director Dale Compton (center) and Ames Deputy Director Sy Syvertson (right)

  2. NASA Ames Fluid Mechanics Laboratory research briefs

    Science.gov (United States)

    Davis, Sanford (Editor)

    1994-01-01

    The Ames Fluid Mechanics Laboratory research program is presented in a series of research briefs. Nineteen projects covering aeronautical fluid mechanics and related areas are discussed and augmented with the publication and presentation output of the Branch for the period 1990-1993.

  3. Companions of Bright Barred Shapley Ames Galaxies

    OpenAIRE

    Garcia-Barreto, J. Antonio; Carrillo, Rene; Vera-Villamizar, Nelson

    2003-01-01

    Companion galaxy environment for a subset of 78 bright and nearby barred galaxies from the Shapley Ames Catalog is presented. Among spiral barred galaxies there are Seyfert galaxies, galaxies with circumnuclear structures, galaxies not associated with any large scale galaxy cloud structure, galaxies with peculiar disk morphology (crooked arms) and galaxies with normal disk morphology; the list includes all Hubble types. The companion galaxy list includes number of companion galaxies within 20...

  4. Center Overview and UAV Highlights at NASA Ames Research Center

    Science.gov (United States)

    Feng, Deborah; Yan, Jerry Chi Yiu

    2017-01-01

    The PowerPoint presentation gives an overview of NASA Ames Research Center and its core competencies, as well as some of the highlights of Unmanned Aerial Vehicle (UAV) and Unmanned Aircraft Systems (UAS) accomplishments and innovations by researchers at Ames.

  5. Radiological survey support activities for the decommissioning of the Ames Laboratory Research Reactor Facility, Ames, Iowa

    Energy Technology Data Exchange (ETDEWEB)

    Wynveen, R.A.; Smith, W.H.; Sholeen, C.M.; Justus, A.L.; Flynn, K.F.

    1984-09-01

    At the request of the Engineering Support Division of the US Department of Energy-Chicago Operations Office and in accordance with the programmatic overview/certification responsibilities of the Department of Energy Environmental and Safety Engineering Division, the Argonne National Laboratory Radiological Survey Group conducted a series of radiological measurements and tests at the Ames Laboratory Research Reactor located in Ames, Iowa. These measurements and tests were conducted during 1980 and 1981 while the reactor building was being decontaminated and decommissioned for the purpose of returning the building to general use. The results of these evaluations are included in this report. Although the surface contamination within the reactor building could presumably be reduced to negligible levels, the potential for airborne contamination from tritiated water vapor remains. This vapor emmanates from contamination within the concrete of the building and should be monitored until such time as it is reduced to background levels. 2 references, 8 figures, 6 tables.

  6. NASA Ames UV-LED Poster Overview

    Science.gov (United States)

    Jaroux, Belgacem Amar

    2015-01-01

    UV-LED is a small satellite technology demonstration payload being flown on the Saudisat-4 spacecraft that is demonstrating non-contacting charge control of an isolated or floating mass using new solid-state ultra-violet light emitting diodes (UV-LEDs). Integrated to the rest of the spacecraft and launched on a Dnepr in June 19, 2014, the project is a collaboration between the NASA Ames Research Center (ARC), Stanford University, and King Abdulaziz City for Science and Technology (KACST). Beginning with its commissioning in December, 2015, the data collected by UV-LED have validated a novel method of charge control that will improve the performance of drag-free spacecraft allowing for concurrent science collection during charge management operations as well as reduce the mass, power and volume required while increasing lifetime and reliability of a charge management subsystem. UV-LED continues to operate, exploring new concepts in non-contacting charge control and collecting data crucial to understanding the lifetime of ultra-violet light emitting diodes in space. These improvements are crucial to the success of ground breaking missions such as LISA and BBO, and demonstrates the ability of low cost small satellite missions to provide technological advances that far exceed mission costs.

  7. AME position statement on adrenal incidentaloma.

    Science.gov (United States)

    Terzolo, M; Stigliano, A; Chiodini, I; Loli, P; Furlani, L; Arnaldi, G; Reimondo, G; Pia, A; Toscano, V; Zini, M; Borretta, G; Papini, E; Garofalo, P; Allolio, B; Dupas, B; Mantero, F; Tabarin, A

    2011-06-01

    To assess currently available evidence on adrenal incidentaloma and provide recommendations for clinical practice. A panel of experts (appointed by the Italian Association of Clinical Endocrinologists (AME)) appraised the methodological quality of the relevant studies, summarized their results, and discussed the evidence reports to find consensus. Unenhanced computed tomography (CT) is recommended as the initial test with the use of an attenuation value of ≤10 Hounsfield units (HU) to differentiate between adenomas and non-adenomas. For tumors with a higher baseline attenuation value, we suggest considering delayed contrast-enhanced CT studies. Positron emission tomography (PET) or PET/CT should be considered when CT is inconclusive, whereas fine needle aspiration biopsy may be used only in selected cases suspicious of metastases (after biochemical exclusion of pheochromocytoma). HORMONAL ASSESSMENT: Pheochromocytoma and excessive overt cortisol should be ruled out in all patients, whereas primary aldosteronism has to be considered in hypertensive and/or hypokalemic patients. The 1 mg overnight dexamethasone suppression test is the test recommended for screening of subclinical Cushing's syndrome (SCS) with a threshold at 138 nmol/l for considering this condition. A value of 50 nmol/l virtually excludes SCS with an area of uncertainty between 50 and 138 nmol/l. Surgery is recommended for masses with suspicious radiological aspects and masses causing overt catecholamine or steroid excess. Data are insufficient to make firm recommendations for or against surgery in patients with SCS. However, adrenalectomy may be considered when an adequate medical therapy does not reach the treatment goals of associated diseases potentially linked to hypercortisolism.

  8. Functionally enhanced brown adipose tissue in Ames dwarf mice.

    Science.gov (United States)

    Darcy, Justin; Bartke, Andrzej

    2017-01-02

    Reduced insulin-like growth factor 1/insulin signaling (IIS) has been linked to extended longevity in species ranging from yeast to mammals. In mammals, this is exemplified in Ames dwarf (Prop1 df/df ) mice, which have a 40%-60% increase in longevity (males and females, respectively) due to their recessive Prop1 loss-of-function mutation that results in lack of growth hormone (GH), thyroid-stimulating hormone and prolactin. Our laboratory has previously shown that Ames dwarf mice have functionally unique white adipose tissue (WAT) that improves, rather than impairs, insulin sensitivity. Because GH and thyroid hormone are integral to adipose tissue development and function, we hypothesized that brown adipose tissue (BAT) in Ames dwarf mice may also be functionally unique and/or enhanced. Here, we elaborate on our recent findings, which demonstrate that BAT is functionally enhanced in Ames dwarf mice, and suggest that BAT removal in these mice results in utilization of WAT depots as an energy source. We also discuss how our findings compare to those in other long-lived dwarf mice with altered IIS, which unlike Ames dwarf mice, are essentially euthyroid. Lastly, we provide some insights into the implications of these findings and discuss some of the necessary future work in this area.

  9. Building Climate Resilience at NASA Ames Research Center

    Science.gov (United States)

    Iraci, L. T.; Mueller, C.; Podolske, J. R.; Milesi, C.

    2016-12-01

    NASA Ames Research Center, located at the southern end of the San Francisco Bay (SFB) estuary, has identified three primary vulnerabilities to changes in climate. The Ames Climate Adaptation Science Investigator (CASI) workgroup has studied each of these challenges to operations and the potential exposure of infrastructure and employees to an increased frequency of hazards. Sea level rise inundation scenarios for the SFB Area generally refer to projected scenarios in mean sea level rather than changes in extreme tides that could occur during future storm conditions. In the summer of 2014, high resolution 3-D mapping of the low-lying portion of Ames was performed. Those data are integrated with improved sea level inundation scenarios to identify the buildings, basements and drainage systems potentially affected. We will also identify the impacts of sea level and storm surge effects on transportation to and from the Center. This information will help Center management develop future master plans. Climate change will also lead to changes in temperature, storm frequency and intensity. These changes have potential impacts on localized floods and ecosystems, as well as on electricity and water availability. Over the coming decades, these changes will be imposed on top of ongoing land use and land cover changes, especially those deriving from continued urbanization and increase in impervious surface areas. These coupled changes have the potential to create a series of cascading impacts on ecosystems, including changes in primary productivity and disturbance of hydrological properties and increased flood risk. The majority of the electricity used at Ames is supplied by hydroelectric dams, which will be influenced by reductions in precipitation or changes in the timing or phase of precipitation which reduces snow pack. Coupled with increased demand for summertime air conditioning and other cooling needs, NASA Ames is at risk for electricity shortfalls. To assess the

  10. General Reevaluation Report, Upper Skunk River Basin, Iowa (Ames Lake).

    Science.gov (United States)

    1987-07-01

    February 1985, Corps representatives ’-nade presentations on the reevaluation study to the American Society of Civil Kog ineer , Water Resources Design...SCS near County Line Site S36, T8N, R25W Boone County A-17 SECTION 8 - LOCAL FLOOD PROTECCIoN - AMES, IOWA GENERAL The project area for this flood...CentraltDivision ATTN: NCDPO 1. We approve your recommendation to reclassify the Ames lake, Iowa, project from the "inactive" to "active" category of Civil

  11. Ames and other European networks in integrity of ageing structures

    International Nuclear Information System (INIS)

    Davies, L.M.; Von Estorff, U.; Crutzen, S.

    1996-01-01

    Several European institutions and organisations and the Joint Research Centre have developed co-operative programmes now organised into Networks for mutual benefit. They include utilities, engineering companies, Research and Development laboratories and regulatory bodies. Networks are organised and managed like the successful Programme for the Inspection of Steel Components (PISC). The JRC's Institute for Advanced Materials of the European Commission plays the role of Operating Agent and manager of these Networks: ENIQ. AMES, NESC, each of them dealing with specific aspect of fitness for purpose of materials in structural components. This paper describes the structure and the objectives of these networks. Particular emphasis is given to the network AMES

  12. Comparison Between Field Data and NASA Ames Wind Tunnel Data

    Energy Technology Data Exchange (ETDEWEB)

    Corbus, D.

    2005-11-01

    The objective of this analysis is to compare the measured data from the NASA Ames wind tunnel experiment to those collected in the field at the National Wind Technology Center (NWTC) with the same turbine configuration. The results of this analysis provide insight into what measurements can be made in the field as opposed to wind tunnel testing.

  13. Isamaaliit teeb Navitrollaga kaupa

    Index Scriptorium Estoniae

    1999-01-01

    Valdavalt Navitrolla teostega kauplevale Obu galeriile tehti ettepanek galerii Isamaaliidu valimisstaabiks välja rentida. Keelduti, kuna lepingus Tartu linnaga on galerii kohuststud tegelema vaid põhitegevusega

  14. Future Directions in Rotorcraft Technology at Ames Research Center

    Science.gov (United States)

    Aiken, Edwin W.; Ormiston, Robert A; Young, Larry A.

    2000-01-01

    Members of the NASA and Army rotorcraft research community at Ames Research Center have developed a vision for 'Vertical Flight 2025'. This paper describes the development of that vision and the steps being taken to implement it. In an effort to realize the vision, consistent with both NASA and Army Aviation strategic plans, two specific technology development projects have been identified: (1) one focused on a personal transportation system capable of vertical flight (the 'Roto-Mobile') and (2) the other on small autonomous rotorcraft (which is inclusive of vehicles which range in grams of gross weight for 'MicroRotorcraft' to thousands of kilograms for rotorcraft uninhabited aerial vehicles). The paper provides a status report on these projects as well as a summary of other revolutionary research thrusts being planned and executed at Ames Research Center.

  15. NASA Ames and Future of Space Exploration, Science, and Aeronautics

    Science.gov (United States)

    Cohen, Jacob

    2015-01-01

    Pushing the frontiers of aeronautics and space exploration presents multiple challenges. NASA Ames Research Center is at the forefront of tackling these issues, conducting cutting edge research in the fields of air traffic management, entry systems, advanced information technology, intelligent human and robotic systems, astrobiology, aeronautics, space, earth and life sciences and small satellites. Knowledge gained from this research helps ensure the success of NASA's missions, leading us closer to a world that was only imagined as science fiction just decades ago.

  16. Ames T-3 fire test facility - Aircraft crash fire simulation

    Science.gov (United States)

    Fish, R. H.

    1976-01-01

    There is a need to characterize the thermal response of materials exposed to aircraft fuel fires. Large scale open fire tests are costly and pollute the local environment. This paper describes the construction and operation of a subscale fire test that simulates the heat flux levels and thermochemistry of typical open pool fires. It has been termed the Ames T-3 Test and has been used extensively by NASA since 1969 to observe the behavior of materials exposed to JP-4 fuel fires.

  17. Phospholipid composition and longevity: lessons from Ames dwarf mice.

    Science.gov (United States)

    Valencak, Teresa G; Ruf, Thomas

    2013-12-01

    Membrane fatty acid (FA) composition is correlated with longevity in mammals. The "membrane pacemaker hypothesis of ageing" proposes that animals which cellular membranes contain high amounts of polyunsaturated FAs (PUFAs) have shorter life spans because their membranes are more susceptible to peroxidation and further oxidative damage. It remains to be shown, however, that long-lived phenotypes such as the Ames dwarf mouse have membranes containing fewer PUFAs and thus being less prone to peroxidation, as would be predicted from the membrane pacemaker hypothesis of ageing. Here, we show that across four different tissues, i.e., muscle, heart, liver and brain as well as in liver mitochondria, Ames dwarf mice possess membrane phospholipids containing between 30 and 60 % PUFAs (depending on the tissue), which is similar to PUFA contents of their normal-sized, short-lived siblings. However, we found that that Ames dwarf mice membrane phospholipids were significantly poorer in n-3 PUFAs. While lack of a difference in PUFA contents is contradicting the membrane pacemaker hypothesis, the lower n-3 PUFAs content in the long-lived mice provides some support for the membrane pacemaker hypothesis of ageing, as n-3 PUFAs comprise those FAs being blamed most for causing oxidative damage. By comparing tissue composition between 1-, 2- and 6-month-old mice in both phenotypes, we found that membranes differed both in quantity of PUFAs and in the prevalence of certain PUFAs. In sum, membrane composition in the Ames dwarf mouse supports the concept that tissue FA composition is related to longevity.

  18. Ames Laboratory Site Environmental Report, Calendar year 1991

    International Nuclear Information System (INIS)

    Mathison, L.

    1991-01-01

    The summarized data and conclusions from the Ames Laboratory environmental monitoring program are presented in this Annual Site Environmental Report. This program is a working requirement of Department of Energy (DOE) Order 5484.1, ''Environmental Protection, Safety, and Health Protection Information Reporting Requirements'' and Order 5400.1, ''General Environmental Protection Program.'' Ames Laboratory is located on the campus of Iowa State University (ISU) and occupies several buildings owned by the DOE. The Laboratory also leases space in ISU-owned buildings. Laboratory research activities involve less than ten percent of the total chemical use and one percent of the radioisotope use on the ISU campus. Ames Laboratory is responsible for a small chemical burial site, located on ISU property. The site was used for the disposal of chemical and metal slags from thorium and uranium production. Samples of water from existing test wells and upstream and downstream sites on the nearby Squaw Creek show no detectable migration of the contents of the burial site. A Site Assessment plan submitted to the State of Iowa Department of Natural Resources (DNR) was approved. A Remedial Investigation/Feasibility Study work plan has been completed for additional studies at the site. This has been reviewed and approved by the DOE Chicago Field Office and the DNR. A National Environmental Policy Act (NEPA) review of the site resulted in a categorical exclusion finding which has been approved by the DOE. Ames Laboratory has an area contaminated by diesel fuel at the location of a storage tank which was removed in 1970. Soil corings and groundwater have been analyzed for contamination and an assessment written. Pollution awareness and waste minimization programs and plans were implemented in 1990. Included in this effort was the implementation of a waste white paper and green computer paper recycling program

  19. Unique life sciences research facilities at NASA Ames Research Center

    Science.gov (United States)

    Mulenburg, G. M.; Vasques, M.; Caldwell, W. F.; Tucker, J.

    1994-01-01

    The Life Science Division at NASA's Ames Research Center has a suite of specialized facilities that enable scientists to study the effects of gravity on living systems. This paper describes some of these facilities and their use in research. Seven centrifuges, each with its own unique abilities, allow testing of a variety of parameters on test subjects ranging from single cells through hardware to humans. The Vestibular Research Facility allows the study of both centrifugation and linear acceleration on animals and humans. The Biocomputation Center uses computers for 3D reconstruction of physiological systems, and interactive research tools for virtual reality modeling. Psycophysiological, cardiovascular, exercise physiology, and biomechanical studies are conducted in the 12 bed Human Research Facility and samples are analyzed in the certified Central Clinical Laboratory and other laboratories at Ames. Human bedrest, water immersion and lower body negative pressure equipment are also available to study physiological changes associated with weightlessness. These and other weightlessness models are used in specialized laboratories for the study of basic physiological mechanisms, metabolism and cell biology. Visual-motor performance, perception, and adaptation are studied using ground-based models as well as short term weightlessness experiments (parabolic flights). The unique combination of Life Science research facilities, laboratories, and equipment at Ames Research Center are described in detail in relation to their research contributions.

  20. Ames Laboratory Site Environmental Report, Calendar year 1992

    International Nuclear Information System (INIS)

    1992-01-01

    The summarized data and conclusions from the Ames Laboratory environmental monitoring program are presented in this Annual Site Environmental Report. Pollution awareness and waste minimization programs and plans implemented in 1990 are continuing to date. Ames Laboratory (AL) is responsible for a small chemical burial site, located on ISU property. The site was used for the disposal of chemical and metal slags from thorium and uranium production. Samples of water from existing test wells, and upstream and downstream sites on the nearby Squaw Creek, have not detected migration of the buried materials off site. Surface, hand auger and deep boring soil samples have been collected from the site. The analytical results are pending, Six new monitoring wells have been installed and sampled. Analytical results are pending. Ames Laboratory is responsible for an area contaminated by diesel fuel that leaked from an underground storage tank (UST) in 1970. The tank was removed that year. Soil borings and groundwater have been analyzed for contamination and a preliminary assessment written. Nine small inactive waste sites have been identified for characterization. The NEPA review for this work resulted in a CX determination. The work plans were approved by AL and CH. A subcontractor has surveyed and sampled the sites. Analytical results are pending

  1. Spatial delayed nonmatching-to-sample performances in long-living Ames dwarf mice.

    Science.gov (United States)

    Derenne, Adam; Brown-Borg, Holly M; Martner, Sarah; Wolff, Wendy; Frerking, Morgan

    2014-01-17

    Ames dwarf mice have an extended lifespan by comparison with normal mice. Behavioral testing has revealed that sometimes Ames dwarf mice also evince superior performances relative to normal mice, but in other cases they do not. In this experiment, Ames dwarf and normal mice were compared on a T-maze test and on a delayed nonmatching-to-sample variant of a T-maze test. On the simple T-maze, Ames dwarf and normal mice committed comparable numbers of errors. On the nonmatching-to-sample task, normal mice mastered the discrimination by the end of the experiment while Ames dwarf mice did not. The apparatus, distances traveled and session duration were equivalent between the two tasks. The poorer performances of Ames dwarf mice on the nonmatching-to-sample task suggests that Ames dwarf mice may not be as capable of learning relatively cognitively complex tasks as normal mice. © 2013.

  2. Groundwater hydrology study of the Ames Chemical Disposal Site

    International Nuclear Information System (INIS)

    Stickel, T.

    1996-01-01

    The Ames Laboratory Chemical Disposal Site is located in northwestern Ames, Iowa west of Squaw Creek. From 1957 to 1966, Ames Laboratory conducted research to develop processes to separate uranium and thorium from nuclear power fuel and to separate yttrium from neutron shielding sources. The wastes from these processes, which contained both hazardous and radiological components, were placed into nine burial pits. Metal drums, plywood boxes, and steel pails were used to store the wastes. Uranium was also burned on the ground surface of the site. Monitoring wells were placed around the waste burial pits. Groundwater testing in 1993 revealed elevated levels of Uranium 234, Uranium 238, beta and alpha radiation. The north side of the burial pit had elevated levels of volatile organic compounds. Samples in the East Ravine showed no volatile organics; however, they did contain elevated levels of radionuclides. These analytical results seem to indicate that the groundwater from the burial pit is flowing down hill and causing contamination in the East Ravine. Although there are many avenues for the contamination to spread, the focus of this project is to understand the hydrogeology of the East Ravine and to determine the path of groundwater flow down the East Ravine. The groundwater flow data along with other existing information will be used to assess the threat of chemical migration down the East Ravine and eventually off-site. The primary objectives of the project were as follows: define the geology of the East Ravine; conduct slug tests to determine the hydraulic conductivity of both oxidized and unoxidized till; develop a three-dimensional mathematical model using ModIME and MODFLOW to simulate groundwater flow in the East Ravine

  3. Voluntary cleanup of the Ames chemical disposal site

    International Nuclear Information System (INIS)

    Taboas, A.L.; Freeman, R.; Peterson, J.

    2003-01-01

    The U.S. Department of Energy completed a voluntary removal action at the Ames chemical disposal site, a site associated with the early days of the Manhattan Project. It contained chemical and low-level radioactive wastes from development of the technology to extract uranium from uranium oxide. The process included the preparation of a Remedial Investigation, Feasibility Study, Baseline Risk Assessment, and, ultimately, issuance of a Record of Decision. Various stakeholder groups were involved, including members of the regulatory community, the general public, and the landowner, Iowa State University. The site was restored and returned to the landowner for unrestricted use.

  4. Evolutionary Ensemble for In Silico Prediction of Ames Test Mutagenicity

    Science.gov (United States)

    Chen, Huanhuan; Yao, Xin

    Driven by new regulations and animal welfare, the need to develop in silico models has increased recently as alternative approaches to safety assessment of chemicals without animal testing. This paper describes a novel machine learning ensemble approach to building an in silico model for the prediction of the Ames test mutagenicity, one of a battery of the most commonly used experimental in vitro and in vivo genotoxicity tests for safety evaluation of chemicals. Evolutionary random neural ensemble with negative correlation learning (ERNE) [1] was developed based on neural networks and evolutionary algorithms. ERNE combines the method of bootstrap sampling on training data with the method of random subspace feature selection to ensure diversity in creating individuals within an initial ensemble. Furthermore, while evolving individuals within the ensemble, it makes use of the negative correlation learning, enabling individual NNs to be trained as accurate as possible while still manage to maintain them as diverse as possible. Therefore, the resulting individuals in the final ensemble are capable of cooperating collectively to achieve better generalization of prediction. The empirical experiment suggest that ERNE is an effective ensemble approach for predicting the Ames test mutagenicity of chemicals.

  5. Penentuan Titik Lokasi Pelabuhan Penyeberangan Amed Di Kabupaten Karangasem

    Directory of Open Access Journals (Sweden)

    I Gusti Ngurah Putra Dirgayusa

    2016-07-01

    Full Text Available Accumulation of social activity, economy and transportation that occur in Southern part of Bali adversely affects at transportation infrastructure carrying activity in this area. These require the government to get the solution of this problem. Through spatial planning area of Bali province 2005, governments establish Amed Bay developed as crossing harbor. These cases mean to divide the shout hem traffic line and support the development in northern part of Bali. The object of this research is in Purwakerti village, district of Abang, Karangasem regency. Research held based on technical and legality review. In advance analyze of those aspects that established some alterative potential location based on area requirement and mapping survey result. Following, each location alternative disassembly and examined their advantages and disadvantages in each aspect. Technical aspect analyze of land and territorial water technique. The approach that used in harbor location selection for this technique is weighting and assessment method in assessment matrix. The weighting value that used refers to harbor location selection in Makian bay. Meanwhile, for legality aspect, analyzed by policy review that relate to spatial area and location selection of harbor development. Based on minimum area demand analyze that 0.7 Ha for land facilities and 15.8 Ha for waters facilities. Refers to minimum area demand and layout spatial survey, four locations are selected for alternative points. After technical and legality aspect analyzed, then obtained second area chosen which located in Amed country, Purwakerti village.

  6. NASA Ames Sustainability Initiatives: Aeronautics, Space Exploration, and Sustainable Futures

    Science.gov (United States)

    Grymes, Rosalind A.

    2015-01-01

    In support of the mission-specific challenges of aeronautics and space exploration, NASA Ames produces a wealth of research and technology advancements with significant relevance to larger issues of planetary sustainability. NASA research on NexGen airspace solutions and its development of autonomous and intelligent technologies will revolutionize both the nation's air transporation systems and have applicability to the low altitude flight economy and to both air and ground transporation, more generally. NASA's understanding of the Earth as a complex of integrated systems contributes to humanity's perception of the sustainability of our home planet. Research at NASA Ames on closed environment life support systems produces directly applicable lessons on energy, water, and resource management in ground-based infrastructure. Moreover, every NASA campus is a 'city'; including an urbanscape and a workplace including scientists, human relations specialists, plumbers, engineers, facility managers, construction trades, transportation managers, software developers, leaders, financial planners, technologists, electricians, students, accountants, and even lawyers. NASA is applying the lessons of our mission-related activities to our urbanscapes and infrastructure, and also anticipates a leadership role in developing future environments for living and working in space.

  7. Brown Adipose Tissue Function Is Enhanced in Long-Lived, Male Ames Dwarf Mice

    Science.gov (United States)

    McFadden, Samuel; Fang, Yimin; Huber, Joshua A.; Zhang, Chi; Sun, Liou Y.; Bartke, Andrzej

    2016-01-01

    Ames dwarf mice (Prop1df/df) are long-lived due to a loss of function mutation, resulting in deficiency of GH, TSH, and prolactin. Along with a marked extension of longevity, Ames dwarf mice have improved energy metabolism as measured by an increase in their oxygen consumption and heat production, as well as a decrease in their respiratory quotient. Along with alterations in energy metabolism, Ames dwarf mice have a lower core body temperature. Moreover, Ames dwarf mice have functionally altered epididymal white adipose tissue (WAT) that improves, rather than impairs, their insulin sensitivity due to a shift from pro- to anti-inflammatory cytokine secretion. Given the unique phenotype of Ames dwarf epididymal WAT, their improved energy metabolism, and lower core body temperature, we hypothesized that Ames dwarf brown adipose tissue (BAT) may function differently from that of their normal littermates. Here we use histology and RT-PCR to demonstrate that Ames dwarf mice have enhanced BAT function. We also use interscapular BAT removal to demonstrate that BAT is necessary for Ames dwarf energy metabolism and thermogenesis, whereas it is less important for their normal littermates. Furthermore, we show that Ames dwarf mice are able to compensate for loss of interscapular BAT by using their WAT depots as an energy source. These findings demonstrate enhanced BAT function in animals with GH and thyroid hormone deficiencies, chronic reduction of body temperature, and remarkably extended longevity. PMID:27740871

  8. Scientific visualization in computational aerodynamics at NASA Ames Research Center

    Science.gov (United States)

    Bancroft, Gordon V.; Plessel, Todd; Merritt, Fergus; Walatka, Pamela P.; Watson, Val

    1989-01-01

    The visualization methods used in computational fluid dynamics research at the NASA-Ames Numerical Aerodynamic Simulation facility are examined, including postprocessing, tracking, and steering methods. The visualization requirements of the facility's three-dimensional graphical workstation are outlined and the types hardware and software used to meet these requirements are discussed. The main features of the facility's current and next-generation workstations are listed. Emphasis is given to postprocessing techniques, such as dynamic interactive viewing on the workstation and recording and playback on videodisk, tape, and 16-mm film. Postprocessing software packages are described, including a three-dimensional plotter, a surface modeler, a graphical animation system, a flow analysis software toolkit, and a real-time interactive particle-tracer.

  9. Reduced Crew Operations Research at NASA Ames Research Center

    Science.gov (United States)

    Brandt, Summer L.; Lachter, Joel

    2017-01-01

    In 2012, NASA began exploring the feasibility of single pilot reduced crew operations (SPORCO) in the context of scheduled passenger air carrier operations (i.e., Parts 121 and 135). This research was spurred by two trends in aviation research: the trend toward reducing costs and a shortage of pilots. A series of simulations were conducted to develop tools and a concept of operations to support RCO. This slide deck is a summary of the NASA Ames RCO research prepared for an R T team at Airbus. Airbus is considering moving forward with reducing crew during the cruise phase of flight with long-haul flights and is interested in the work we have completed.

  10. Mutagenicity of Flavonoids Assayed by Bacterial Reverse Mutation (Ames Test

    Directory of Open Access Journals (Sweden)

    Eliana Aparecida Varanda

    2012-05-01

    Full Text Available The mutagenicity of ten flavonoids was assayed by the Ames test, in Salmonella typhimurium strains TA98, TA100 and TA102, with the aim of establishing hydroxylation pattern-mutagenicity relationship profiles. The compounds assessed were: quercetin, kaempferol, luteolin, fisetin, chrysin, galangin, flavone, 3-hydroxyflavone, 5-hydroxyflavone and 7-hydroxyflavone. In the Ames assay, quercetin acted directly and its mutagenicity increased with metabolic activation. In the presence of S9 mix, kaempferol and galangin were mutagenic in the TA98 strain and kaempferol showed signs of mutagenicity in the other strains. The absence of hydroxyl groups, as in flavone, only signs of mutagenicity were shown in strain TA102, after metabolization and, among monohydroxylated flavones (3-hydroxyflavone, 5-hydroxyflavone and 7-hydroxyflavone, the presence of hydroxyl groups only resulted in minor changes. Luteolin and fisetin also showed signs of mutagenicity in strain TA102. Finally, chrysin, which has only two hydroxy groups, at the 5-OH and 7-OH positions, also did not induce mutagenic activity in any of the bacterial strains used, under either activation condition. All the flavonoids were tested at concentrations varying from 2.6 to 30.7 nmol/plate for galangin and 12.1 to 225.0 nmol/plate for other flavonoids. In light of the above, it is necessary to clarify the conditions and the mechanisms that mediate the biological effects of flavonoids before treating them as therapeutical agents, since some compounds can be biotransformed into more genotoxic products; as is the case for galangin, kaempferol and quercetin.

  11. Ames Laboratory site environmental report, Calendar year 1994

    International Nuclear Information System (INIS)

    1994-01-01

    The Ames Laboratory conducts fundamental research in the physical, chemical, materials, and mathematical sciences and engineering which underlie energy generating, conversion, transmission and storage technologies, environmental improvement, and other technical areas essential to national needs. These efforts will be maintained so as to contribute to the achievement of the vision of DOE and, more specifically, to increase the general levels of knowledge and technical capabilities, to prepare engineering and physical sciences students for the future, both academia and industry, and to develop new technologies and practical applications from our basic scientific programs that will contribute to a strengthening of the US economy. The Laboratory approaches all its operations with the safety and health of all workers as a constant objective and with genuine concern for the environment. The Laboratory relies upon its strengths in materials synthesis and processing, materials reliability, chemical analysis, chemical sciences, photosynthesis, materials sciences, metallurgy, high-temperature superconductivity, and applied mathematical sciences to conduct the long term basic and intermediate range applied research needed to solve the complex problems encountered in energy production, and utilization as well as environmental restoration and waste management. Ames Laboratory will continue to maintain a very significant and highly beneficial pre-college math and science education program which currently serves both teachers and students at the middle school and high school levels. Our technology transfer program is aided by joint efforts with ISU's technology development and commercialization enterprise and will sustain concerted efforts to implement Cooperative Research and Development Agreements, industrially sponsored Work for Others projects. and scientific personnel exchanges with our various customers

  12. Health-hazard evaluation report HETA-86-422-1891, City of Ames Municipal Power Plant, Ames, Iowa

    Energy Technology Data Exchange (ETDEWEB)

    Ahrenholz, S.H.

    1988-05-01

    In response to a request from the management of the Municipal Power Facility, Ames, Iowa and the International Union of Electrical Workers Local 234, an evaluation was made of possible health hazards at the work site. Concerns were specifically expressed about the handling and burning of refuse-derived fuel (RDF), asbestos insulation, coal dust, fly ash, hot working environments, polychlorinated biphenyl (PCB) present in grounding transformers, and on site chemical usage and storage. RDF was composed primarily of the shredded combustible part of municipal solid waste. A survey of the facility indicated that potential hazards did exist from noise, heat, asbestos, coal dust, and crystalline silica. The only documented case of over exposure was to coal dust in the coal yard. Metal exposure was very low or nondetectable. The author concludes that hazards existed due to heat levels, noise, potential asbestos exposure, and elevated coal dust and silica exposures. The author makes recommendations.

  13. Do Ames dwarf and calorie-restricted mice share common effects on age-related pathology?

    Directory of Open Access Journals (Sweden)

    Yuji Ikeno

    2013-06-01

    Full Text Available Since 1996, aging studies using several strains of long-lived mutant mice have been conducted. Among these studies, Ames dwarf mice have been extensively examined to seek clues regarding the role of the growth hormone/insulin-like growth factor-1 axis in the aging process. Interestingly, these projects demonstrate that Ames dwarf mice have physiological characteristics that are similar to those seen with calorie restriction, which has been the most effective experimental manipulation capable of extending lifespan in various species. However, this introduces the question of whether Ames dwarf and calorie-restricted (CR mice have an extended lifespan through common or independent pathways. To answer this question, we compared the disease profiles of Ames dwarf mice to their normal siblings fed either ad libitum (AL or a CR diet. Our findings show that the changes in age-related diseases between AL-fed Ames dwarf mice and CR wild-type siblings were similar but not identical. Moreover, the effects of CR on age-related pathology showed similarities and differences between Ames dwarf mice and their normal siblings, indicating that calorie restriction and Ames dwarf mice exhibit their anti-aging effects through both independent and common mechanisms.

  14. Briefing to University of Porto on NASA Airborne Science Program and Ames UAVs

    Science.gov (United States)

    Fladeland, Matthew

    2015-01-01

    NASA Ames is exploring a partnership with the University of Portugal to jointly develop and test new autonomous vehicle technologies. As part of the discussions I will be briefing the University of Portugal faculty on the NASA Airborne Science Program (ASP) and associated activities at NASA Ames Research Center. The presentation will communicate the requirements that drive the program, the assets available to NASA researchers, and discuss research projects that have used unmanned aircraft systems including MIZOPEX, Surprise Valley, and Florida Keys Coral Reef assessment. Other topics will include the SIERRA and Dragon Eye UAV projects operated at Ames.

  15. Making Stuff Outreach at the Ames Laboratory and Iowa State University

    Energy Technology Data Exchange (ETDEWEB)

    Ament, Katherine; Karsjen, Steven; Leshem-Ackerman, Adah; King, Alexander

    2011-04-01

    The U. S. Department of Energy's Ames Laboratory in Ames, Iowa was a coalition partner for outreach activities connected with NOVA's Making Stuff television series on PBS. Volunteers affiliated with the Ames Laboratory and Iowa State University, with backgrounds in materials science, took part in activities including a science-themed Family Night at a local mall, Science Cafes at the Science Center of Iowa, teacher workshops, demonstrations at science nights in elementary and middle schools, and various other events. We describe a selection of the activities and present a summary of their outcomes and extent of their impact on Ames, Des Moines and the surrounding communities in Iowa. In Part 2, results of a volunteer attitude survey are presented, which shed some light on the volunteer experience and show how the volunteers participation in outreach activities has affected their views of materials education.

  16. Mutagenic and antimutagenic activities of bioflavonoids and structural analogues in the Ames/Salmonella test

    NARCIS (Netherlands)

    Mohn GR; Stel JJ van der; Stavenuiter JFC; Hamzink MRJ; Kreijl CF; LEO; LBO

    1996-01-01

    De mutagene en antimutagene eigenschappen van bioflavonoiden werden in de bacteriele mutageniteitstest van Ames met Salmonella typhimurium stammen TA98 en TA100 onderzocht. De volgorde van mutagene activiteit voor beide stammen in aanwezigheid van metabole activering was

  17. Acquisition of steady-state operant behavior in long-living Ames Dwarf mice.

    Science.gov (United States)

    Derenne, Adam; Brown-Borg, Holly; Feltman, Kathryn; Corbett, Grant; Lackman, Serena

    2011-10-24

    Ames dwarf mice have a Prop-1 mutation that has been identified with increased levels of IGF-I in the central nervous system, upregulation of neuroprotective systems, and increased lifespan. To elucidate the behavioral effects of the Prop-1 mutation, 8 Ames dwarf and 7 normal mice (all of whom were 8 months of age or younger) were compared on a differential-reinforcement-of-low-rate-of-responding schedule of reinforcement and a matching-to-sample task. On both tasks, nosepokes were reinforced with access to a saccharin solution. Comparisons were based on several measures of behavioral efficiency: pause durations, intertrial intervals, and numbers of responses. Ames dwarf mice were generally less efficient than normal mice. One possible cause of this outcome is that relatively young Ames dwarf mice show less cognitive development than age-matched normal mice. Copyright © 2011 Elsevier Inc. All rights reserved.

  18. Analysis of Hexanitrostilbene (HNS) and Dipicryethane (DPE) for Mutagenicity by the Ames/Salmonella Assay

    Energy Technology Data Exchange (ETDEWEB)

    Wu, R; Felton, J

    2007-10-12

    The Ames/Salmonella assay, developed by Professor Bruce Ames at the University of California, Berkeley, is a rapid and sensitive assay for detecting mutagenicity of various chemical compounds (Maron and Ames, 1983). It is a widely accepted short-term assay for detecting chemicals that induce mutations in the histidine (his) gene of Salmonella typhimurium. This is a reverse mutation assay that detects the mutational reversion of his-dependent Salmonella to the his-independent counterpart. Thereby, mutagenic compounds will increase the frequency of occurrence of his-independent bacterial colonies. The assay utilizes the specific genetically constructed strains of bacteria either with or without mammalian metabolic activation enzymes (S9), Aroclor induced rat liver homogenate to assess the mutagenicity of different compounds. In this study, we will use the Ames/Salmonella assay to investigate the mutagenicity of Hexanitrostilbene (HNS) from both Bofors and Pantex, and Dipicryethane (DPE).

  19. Ames Stereo Pipeline for Operation IceBridge

    Science.gov (United States)

    Beyer, R. A.; Alexandrov, O.; McMichael, S.; Fong, T.

    2017-12-01

    We are using the NASA Ames Stereo Pipeline to process Operation IceBridge Digital Mapping System (DMS) images into terrain models and to align them with the simultaneously acquired LIDAR data (ATM and LVIS). The expected outcome is to create a contiguous, high resolution terrain model for each flight that Operation IceBridge has flown during its eight year history of Arctic and Antarctic flights. There are some existing terrain models in the NSIDC repository that cover 2011 and 2012 (out of the total period of 2009 to 2017), which were made with the Agisoft Photoscan commercial software. Our open-source stereo suite has been verified to create terrains of similar quality. The total number of images we expect to process is around 5 million. There are numerous challenges with these data: accurate determination and refinement of camera pose when the images were acquired based on data logged during the flights and/or using information from existing orthoimages, aligning terrains with little or no features, images containing clouds, JPEG artifacts in input imagery, inconsistencies in how data was acquired/archived over the entire period, not fully reliable camera calibration files, and the sheer amount of data. We will create the majority of terrain models at 40 cm/pixel with a vertical precision of 10 to 20 cm. In some circumstances when the aircraft was flying higher than usual, those values will get coarser. We will create orthoimages at 10 cm/pixel (with the same caveat that some flights are at higher altitudes). These will differ from existing orthoimages by using the underlying terrain we generate rather than some pre-existing very low-resolution terrain model that may differ significantly from what is on the ground at the time of IceBridge acquisition.The results of this massive processing will be submitted to the NSIDC so that cryosphere researchers will be able to use these data for their investigations.

  20. Investigating the Mutagenic Effects of Three Commonly Used Pulpotomy Agents Using the Ames Test

    OpenAIRE

    Samiei, Mohammad; Asgary, Saeed; Farajzadeh, Malak; Bargahi, Nasrin; Abdolrahimi, Majid; Kananizadeh, Usef; Dastmalchi, Siavoush

    2015-01-01

    Purpose: The mutagenic potency of materials used in dentistry is of great concern. The Ames test is a bacterial reverse mutation assay, which is used to determine the mutagenicity potential of chemicals. In this study, the Ames test was used to compare mutagenic effects of three pulpotomy agents, namely, CEM cement, formocresol and ferric sulfate. Methods: TA100 strain of Salmonella typhimurium was used to evaluate mutagenicity of different concentrations of pulpotomy materials in the pres...

  1. Mitochondrial electron transport chain functions in long-lived Ames dwarf mice

    Science.gov (United States)

    Choksi, Kashyap B.; Nuss, Jonathan E.; DeFord, James H.; Papaconstantinou, John

    2011-01-01

    The age-associated decline in tissue function has been attributed to ROS-mediated oxidative damage due to mitochondrial dysfunction. The long-lived Ames dwarf mouse exhibits resistance to oxidative stress, a physiological characteristic of longevity. It is not known, however, whether there are differences in the electron transport chain (ETC) functions in Ames tissues that are associated with their longevity. In these studies we analyzed enzyme activities of ETC complexes, CI-CV and the coupled CI-CII and CII-CIII activities of mitochondria from several tissues of young, middle aged and old Ames dwarf mice and their corresponding wild type controls to identify potential mitochondrial prolongevity functions. Our studies indicate that post-mitotic heart and skeletal muscle from Ames and wild-type mice show similar changes in ETC complex activities with aging, with the exception of complex IV. Furthermore, the kidney, a slowly proliferating tissue, shows dramatic differences in ETC functions unique to the Ames mice. Our data show that there are tissue specific mitochondrial functions that are characteristic of certain tissues of the long-lived Ames mouse. We propose that this may be a factor in the determination of extended lifespan of dwarf mice. PMID:21934186

  2. Hepatic response to oxidative injury in long-lived Ames dwarf mice.

    Science.gov (United States)

    Sun, Liou Y; Bokov, Alex F; Richardson, Arlan; Miller, Richard A

    2011-01-01

    Multiple stress resistance pathways were evaluated in the liver of Ames dwarf mice before and after exposure to the oxidative toxin diquat, seeking clues to the exceptional longevity conferred by this mutation. Before diquat treatment, Ames dwarf mice, compared with nonmutant littermate controls, had 2- to 6-fold higher levels of expression of mRNAs for immediate early genes and 2- to 5-fold higher levels of mRNAs for genes dependent on the transcription factor Nrf2. Diquat led to a 2-fold increase in phosphorylation of the stress kinase ERK in control (but not Ames dwarf) mice and to a 50% increase in phosphorylation of the kinase JNK2 in Ames dwarf (but not control) mice. Diquat induction of Nrf2 protein was higher in dwarf mice than in controls. Of 6 Nrf2-responsive genes evaluated, 4 (HMOX, NQO-1, MT-1, and MT-2) remained 2- to 10-fold lower in control than in dwarf liver after diquat, and the other 2 (GCLM and TXNRD) reached levels already seen in dwarf liver at baseline. Thus, livers of Ames dwarf mice differ systematically from controls in multiple stress resistance pathways before and after exposure to diquat, suggesting mechanisms for stress resistance and extended longevity in Ames dwarf mice.

  3. Mixing alcohol with energy drink (AMED) and total alcohol consumption: a systematic review and meta-analysis.

    Science.gov (United States)

    Verster, Joris C; Benson, Sarah; Johnson, Sean J; Scholey, Andrew; Alford, Chris

    2016-01-01

    It has been suggested that consuming alcohol mixed with energy drink (AMED) may increase total alcohol consumption. Aims of this systematic review and meta-analysis were (i) to compare alcohol consumption of AMED consumers with alcohol only (AO) consumers (between-group comparisons), and (ii) to examine if alcohol consumption of AMED consumers differs on AMED and AO occasions (within-subject comparisons). A literature search identified fourteen studies. Meta-analyses of between-group comparisons of N = 5212 AMED consumers and N = 12,568 AO consumers revealed that on a typical single drinking episode AMED consumers drink significantly more alcohol than AO consumers (p = 0.0001, ES = 0.536, 95%CI: 0.349 to 0.724). Meta-analyses of within-subject comparisons among N = 2871 AMED consumers revealed no significant difference in overall alcohol consumption on a typical drinking episode between AMED and AO occasions (p = 0.465, ES = -0.052, 95%CI: -0.192 to 0.088). In conclusion, between-group comparisons suggest that heavy alcohol consumption is one of the several phenotypical differences between AMED and AO consumers. Within-subject comparisons revealed, however, that AMED consumption does not increase the total amount of alcohol consumed on a single drinking episode. Copyright © 2016 John Wiley & Sons, Ltd.

  4. Hansapank teeb õppelaenu taotlemise lihtsamaks

    Index Scriptorium Estoniae

    2000-01-01

    Hansapangast õppelaenu soovivad üliõpilased saavad kontrollida internetipanga hanza.netìs, kas laenu saamiseks vajalikud tingimused on nende puhul täidetud ja esitada laenutaotluse hanza.netì või panga kodulehekülje kaudu : [täistekst] / DELFI-uudiseid vahendas Merike Määrits

  5. Vabadus teeb rikkaks / Andres Arrak

    Index Scriptorium Estoniae

    Arrak, Andres, 1958-2017

    2005-01-01

    Autor analüüsib Eesti majandusvabadust kahe edetabelipõhjal: ühte koostab alates 1996. aastast Kanadas asuv Frazeri Instituut, teist USA-s asuv Heritage Foundation ja majandusajakiri The Wall Street Journal. Diagramm: Majandusvabaduse indeksi muutus mullu Euroopa Liidus

  6. ETV teeb Tartu vanglas tantsufilmi

    Index Scriptorium Estoniae

    2005-01-01

    ETV-l valmib koos EFS-i ja Estinfilmiga kultuurikanali ARTE tellimusel tantsufilm "Teine" : režissöör Rene Vilbre : stsenarist Teet Kask : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir

  7. Graafika teeb trikke / Vappu Thurlow

    Index Scriptorium Estoniae

    Thurlow, Vappu, 1960-

    2009-01-01

    6. graafikakonverentsist "Impact" Bristolis. "Impact'i" näituseprogrammist. Eesti graafika oli esindatud Loit Jõekalda koostatud väljapanekuga "Manu propria" (24 eesti graafikut), Kadri Alesmaa ja Jaak Visnapi ning Eve Kase ja Evi Tihemetsa töödega

  8. Ames-2016 line lists for 13 isotopologues of CO2: Updates, consistency, and remaining issues

    Science.gov (United States)

    Huang (黄新川), Xinchuan; Schwenke, David W.; Freedman, Richard S.; Lee, Timothy J.

    2017-12-01

    A new 626-based Ames-2 PES refinement and Ames-2016 line lists for 13 CO2 isotopologues are reported. A consistent σRMS = ±0.02 cm-1 is established for hundreds of isotopologue band origins using the Ames-2 PES. Ames-2016 line lists are computed at 296 K, 1000 K and 4000 K using the Ames-2 PES and the same DMS-N2 dipole surface used previously, with J up to 150, E‧ up to 24,000 cm-1 or 18,000 cm-1 and appropriate intensity cutoffs. The lists are compared to the CDSD-296, CDSD-4000 databases, UCL line lists, and a few recent highly accurate CO2 intensity measurements. Both agreements and discrepancies are discussed. Compared to the old Ames CO2 lists, the Ames-2016 line lists have line position deviations reduced by 50% or more, which consequently leads to more reliable intensities. The line shape parameters in the Ames-2016 line lists are predicted using the newly assigned conventional vibrational polyad quantum numbers for rovibrational levels below 12,000 cm-1 so the quality of the line shape parameters is similar to that of CDSD or HITRAN. This study further proves that a semi-empirically refined PES (Ames-1 and Ames-2) coupled with a high quality ab initio DMS (DMS-N2 and UCL) may generate IR predictions with consistent accuracy and is thus helpful in the analysis of laboratory spectra and simulations of various isotopologues. The Ames-2016 lists based on DMS-N2 have reached the ∼1% intensity prediction accuracy level for the recent 626 30013-00001 and 20013-00001 bands, but further quantification and improvements require sub-percent or sub-half-percent accurate experimental intensities. The inter-isotopologue consistency of the intensity prediction accuracies should have reached better than 1-3% for regular bands not affected by resonances. Since the Effective Dipole Models (EDM) in CDSD and HITRAN have 1-20% or even larger uncertainties, we show that the Ames lists can provide better alternative IR data for many hard-to-determine isotopologue bands

  9. Processing Earth Observing images with Ames Stereo Pipeline

    Science.gov (United States)

    Beyer, R. A.; Moratto, Z. M.; Alexandrov, O.; Fong, T.; Shean, D. E.; Smith, B. E.

    2013-12-01

    ICESat with its GLAS instrument provided valuable elevation measurements of glaciers. The loss of this spacecraft caused a demand for alternative elevation sources. In response to that, we have improved our Ames Stereo Pipeline (ASP) software (version 2.1+) to ingest satellite imagery from Earth satellite sources in addition to its support of planetary missions. This enables the open source community a free method to generate digital elevation models (DEM) from Digital Globe stereo imagery and alternatively other cameras using RPC camera models. Here we present details of the software. ASP is a collection of utilities written in C++ and Python that implement stereogrammetry. It contains utilities to manipulate DEMs, project imagery, create KML image quad-trees, and perform simplistic 3D rendering. However its primary application is the creation of DEMs. This is achieved by matching every pixel between the images of a stereo observation via a hierarchical coarse-to-fine template matching method. Matched pixels between images represent a single feature that is triangulated using each image's camera model. The collection of triangulated features represents a point cloud that is then grid resampled to create a DEM. In order for ASP to match pixels/features between images, it requires a search range defined in pixel units. Total processing time is proportional to the area of the first image being matched multiplied by the area of the search range. An incorrect search range for ASP causes repeated false positive matches at each level of the image pyramid and causes excessive processing times with no valid DEM output. Therefore our system contains automatic methods for deducing what the correct search range should be. In addition, we provide options for reducing the overall search range by applying affine epipolar rectification, homography transform, or by map projecting against a prior existing low resolution DEM. Depending on the size of the images, parallax, and image

  10. Investigating the mutagenic effects of three commonly used pulpotomy agents using the ames test.

    Science.gov (United States)

    Samiei, Mohammad; Asgary, Saeed; Farajzadeh, Malak; Bargahi, Nasrin; Abdolrahimi, Majid; Kananizadeh, Usef; Dastmalchi, Siavoush

    2015-03-01

    The mutagenic potency of materials used in dentistry is of great concern. The Ames test is a bacterial reverse mutation assay, which is used to determine the mutagenicity potential of chemicals. In this study, the Ames test was used to compare mutagenic effects of three pulpotomy agents, namely, CEM cement, formocresol and ferric sulfate. TA100 strain of Salmonella typhimurium was used to evaluate mutagenicity of different concentrations of pulpotomy materials in the presence and absence of enzymatic system found in rat liver S9 fraction. Negative controls were 1% dimethyl sulfoxide and water. The positive controls were sodium azide and 2-aminoanthracene. The number of colonies per plate was counted. The material was regarded mutagenic if the number of histidine revertant colonies was twice or more than the spontaneous revertant colonies (Ames mutagenicity ratio). Ferric sulfate was found mutagenic in the concentrations prepared by addition of 50 µL of its 1 in 100 and 1 in 1000 times diluted solutions to the culture medium in the absence of S9 fraction (Ames test ratios of 2.8 and 2.2, respectively). Formocresol showed strong toxicity toward TA100 strain of S. typhimurium up to the concentration as low achieved using 1000 times diluted solution of the original preparation, particularly in the presence of S9 fraction. Ames assay failed to detect significant reverse mutations in all the concentrations of CEM cement. In contrast to formocresol and ferric sulfate, CEM cement is a less toxic and non-mutagenic agent.

  11. Resolution of contradiction between in silico predictions and Ames test results for four pharmaceutically relevant impurities.

    Science.gov (United States)

    Gunther, William C; Kenyon, Michelle O; Cheung, Jennifer R; Dugger, Robert W; Dobo, Krista L

    2017-12-01

    The ICH M7 Guideline requires low level control of mutagenic impurities in pharmaceutical products to minimize cancer risk in patients (ICHM7, 2014). Bacterial mutagenicity (Ames) data is generally used to determine mutagenic and possible carcinogenic potential of compounds. Recently, a publication on experiences of using two in silico systems to identify potentially mutagenic impurities highlighted the importance of performing a critical review of published Ames data utilized as part of a mutagenicity assessment of impurities (Greene et al., 2015). Four compounds (2-amino-5-hydroxybenzoic acid, 2-amino-3-chlorobenzoic acid, methyl 2-amino-4-chlorobenzoate and 4-morpholinopyridine) reported mutagenic were identified in a two system in silico assessment and expert review of the structuresas non-mutagenic. Likely reasons for mutagenicity could not be identified and the purity of the compounds tested was proposed. In the current investigation, the purest available sample of the four compounds was tested in an OECD-compliant Ames test. The compounds were all found to be non-mutagenic. Possible reasons for the discrepancy between previously reported and current results are discussed. Additionally, important points to consider when conducting an expert review of available Ames data are provided particularly in cases where reported Ames results are discrepant with a two system in silico assessment. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Comparison of Heat Flux Gages for High Enthalpy Flows - NASA Ames and IRS

    Science.gov (United States)

    Loehle, Stefan; Nawaz, Anuscheh; Herdrich, Georg; Fasoulas, Stefanos; Martinez, Edward; Raiche, George

    2016-01-01

    This article is a companion to a paper on heat flux measurements as initiated under a Space Act Agreement in 2011. The current focus of this collaboration between the Institute of Space Systems (IRS) of the University of Stuttgart and NASA Ames Research Center is the comparison and refinement of diagnostic measurements. A first experimental campaign to test different heat flux gages in the NASA Interaction Heating Facility (IHF) and the Plasmawindkanaele (PWK) at IRS was established. This paper focuses on the results of the measurements conducted at IRS. The tested gages included a at face and hemispherical probe head, a 4" hemispherical slug calorimeter, a null-point calorimeter from Ames and a null-point calorimeter developed for this purpose at IRS. The Ames null-point calorimeter was unfortunately defective upon arrival. The measured heat fluxes agree fairly well with each other. The reason for discrepancies can be attributed to signal-to-noise levels and the probe geometry.

  13. Identification of Radiation Effects on Carcinogenic Food Estimated by Ames Test

    International Nuclear Information System (INIS)

    Afifi, M.; Eid, I.; El - Nagdy, M.; Zaher, R.; Abd El-Karem, H.; Abd EL Karim, A.

    2016-01-01

    A major concern in studies related to carcinogenesis is the exposure to the exogenous carcinogens that may occur in food in both natural and polluted human environments. The purpose of the present study is to examine some of food products by Ames test to find out if food products carcinogenic then expose food to gamma radiation to find out the effect of radiation on it as a treatment. In this study, the food samples were examined by Ames test (Salmonella typhimurium mutagenicity test) to find out that a food product could be carcinogenic or highly mutated. Testing of chemicals for mutagenicity is based on the knowledge that a substance which is mutagenic in the bacterium is more likely than not to be a carcinogen in laboratory animals, and thus , by extension, present a risk of cancer to humans. After that food products that showed mutagenicity exposed to gamma radiation at different doses to examine the effect of gamma radiation on food products. This study represent γ radiation effect on carcinogenic food by using Ames test in the following steps: Detect food by Ames test using Salmonella typhimurium strains in which the colony count /plate for each food sample will show if food is slightly mutated or highly mutated or carcinogenic. If food is highly mutated or carcinogenic with high number of colonies /plate, then the carcinogenic food or highly mutated food exposed to different doses of radiation The applied doses in this study were 0, 2.5, 5, and 10 (KGy). Detect the radiation effect on food samples by Ames test after irradiation. The study shows that mutated and carcinogenic food products estimated by Ames test could be treated by irradiation

  14. Corrective Action Plan in response to the March 1992 Tiger Team Assessment of the Ames Laboratory

    International Nuclear Information System (INIS)

    1992-01-01

    On March 5, 1992, a Department of Energy (DOE) Tiger Team completed an assessment of the Ames Laboratory, located in Ames, Iowa. The purpose of the assessment was to provide the Secretary of Energy with a report on the status and performance of Environment, Safety and Health (ES ampersand H) programs at Ames Laboratory. Detailed findings of the assessment are presented in the report, DOE/EH-0237, Tiger Team Assessment of the Ames Laboratory. This document, the Ames Laboratory Corrective Action Plan (ALCAP), presents corrective actions to overcome deficiencies cited in the Tiger Team Assessment. The Tiger Team identified 53 Environmental findings, from which the Team derived four key findings. In the Safety and Health (S ampersand H) area, 126 concerns were identified, eight of which were designated Category 11 (there were no Category I concerns). Seven key concerns were derived from the 126 concerns. The Management Subteam developed 19 findings which have been summarized in four key findings. The eight S ampersand H Category 11 concerns identified in the Tiger Team Assessment were given prompt management attention. Actions to address these deficiencies have been described in individual corrective action plans, which were submitted to DOE Headquarters on March 20, 1992. The ALCAP includes actions described in this early response, as well as a long term strategy and framework for correcting all remaining deficiencies. Accordingly, the ALCAP presents the organizational structure, management systems, and specific responses that are being developed to implement corrective actions and to resolve root causes identified in the Tiger Team Assessment. The Chicago Field Office (CH), IowaState University (ISU), the Institute for Physical Research and Technology (IPRT), and Ames Laboratory prepared the ALCAP with input from the DOE Headquarters, Office of Energy Research (ER)

  15. A Survey of Knowledge Management Research & Development at NASA Ames Research Center

    Science.gov (United States)

    Keller, Richard M.; Clancy, Daniel (Technical Monitor)

    2002-01-01

    This chapter catalogs knowledge management research and development activities at NASA Ames Research Center as of April 2002. A general categorization scheme for knowledge management systems is first introduced. This categorization scheme divides knowledge management capabilities into five broad categories: knowledge capture, knowledge preservation, knowledge augmentation, knowledge dissemination, and knowledge infrastructure. Each of nearly 30 knowledge management systems developed at Ames is then classified according to this system. Finally, a capsule description of each system is presented along with information on deployment status, funding sources, contact information, and both published and internet-based references.

  16. Energy Remote Sensing Applications Projects at the NASA Ames Research Center

    Science.gov (United States)

    Norman, S. D.; Likens, W. C.; Mouat, D. A.

    1982-01-01

    The NASA Ames Research Center is active in energy projects primarily in the role of providing assistance to users in the solution of a number of problems related to energy. Data bases were produced which can be used, in combination with other sources of information, to solve spatially related energy problems. Six project activities at Ames are described which relate to energy and remote sensing. Two projects involve power demand forecasting and estimations using remote sensing and geographic information systems; two others involve transmission line routing and corridor analysis; one involves a synfuel user needs assessment through remote sensing; and the sixth involves the siting of energy facilities.

  17. Mixing alcohol with energy drink (AMED) and total alcohol consumption : a systematic review and meta-analysis

    NARCIS (Netherlands)

    Verster, Joris C|info:eu-repo/dai/nl/241442702; Benson, Sarah; Johnson, Sean J; Scholey, Andrew; Alford, Chris

    It has been suggested that consuming alcohol mixed with energy drink (AMED) may increase total alcohol consumption. Aims of this systematic review and meta-analysis were (i) to compare alcohol consumption of AMED consumers with alcohol only (AO) consumers (between-group comparisons), and (ii) to

  18. Evaluation of Genotoxicity of CSE1034 by Ames and In vitro ...

    African Journals Online (AJOL)

    reverse mutation assay (Ames test) and in vitro chromosomal aberration test. Methods: ... was done with cultured Chinese hamster lung (CHL) cells. Reverse ..... 9. Mirian CP. Chemical-induced DNA damage and human cancer risk. Nat Rev 2004; 4: 630–637. 10. Kada, T.; Ishidate, M. Environmental Mutagens Data.

  19. Mutagenic and antimutagenic activities of bioflavonoids and structural analogues in the Ames/Salmonella test

    NARCIS (Netherlands)

    Mohn GR; Van der Stel JJ; Stavenuiter JFC; Hamzink MRJ; Kreijl CF; LEO; LBO

    1996-01-01

    The mutagenic and antimutagenic properties of bioflavonoids were determined in the bacterial mutagenicity test of Ames, using Salmonella typhimurium strains TA98 and TA100. The decreasing order of mutagenic activity found in both strains was quercetin>myricetin-kaempferol>morin hydrate. The

  20. Improved real gas routines for Sandia's NASA Ames flow field program

    Energy Technology Data Exchange (ETDEWEB)

    Eaton, R.R.; Larson, D.E.

    1976-02-01

    The real gas subroutines in Sandia's version of the NASA Ames flow field code have been extensively revised. Using these modifications the required computer run time for a difficult high Mach number case has been reduced from 1330 seconds to 151 seconds. (auth)

  1. Ames hypopituitary dwarf mice demonstrate imbalanced myelopoiesis between bone marrow and spleen.

    Science.gov (United States)

    Capitano, Maegan L; Chitteti, Brahmananda R; Cooper, Scott; Srour, Edward F; Bartke, Andrzej; Broxmeyer, Hal E

    2015-06-01

    Ames hypopituitary dwarf mice are deficient in growth hormone, thyroid-stimulating hormone, and prolactin. The phenotype of these mice demonstrates irregularities in the immune system with skewing of the normal cytokine milieu towards a more anti-inflammatory environment. However, the hematopoietic stem and progenitor cell composition of the bone marrow (BM) and spleen in Ames dwarf mice has not been well characterized. We found that there was a significant decrease in overall cell count when comparing the BM and spleen of 4-5 month old dwarf mice to their littermate controls. Upon adjusting counts to differences in body weight between the dwarf and control mice, the number of granulocyte-macrophage progenitors, confirmed by immunophenotyping and colony-formation assay was increased in the BM. In contrast, the numbers of all myeloid progenitor populations in the spleen were greatly reduced, as confirmed by colony-formation assays. This suggests that there is a shift of myelopoiesis from the spleen to the BM of Ames dwarf mice; however, this shift does not appear to involve erythropoiesis. The reasons for this unusual shift in spleen to marrow hematopoiesis in Ames dwarf mice are yet to be determined but may relate to the decreased hormone levels in these mice. Copyright © 2015. Published by Elsevier Inc.

  2. General overview of the theories used in assessment: AMEE Guide No. 57.

    NARCIS (Netherlands)

    Schuwirth, L.W.; Vleuten, C.P.M. van der

    2011-01-01

    There are no scientific theories that are uniquely related to assessment in medical education. There are many theories in adjacent fields, however, that can be informative for assessment in medical education, and in the recent decades they have proven their value. In this AMEE Guide we discuss

  3. Ames collaborative study of cosmic-ray neutrons. II. Low- and mid-latitude flights

    International Nuclear Information System (INIS)

    Stephens, L.D.; McCaslin, J.B.; Smith, A.R.; Thomas, R.H.; Hewitt, J.E.; Hughes, L.

    1978-01-01

    The continuing progress of the Ames Collaborative Study of Cosmic Ray Neutrons is described. Data obtained aboard flights from Hawaii at altitudes of 41,000 and 45,000 feet, and in the range of geomagnetic latitude 17 0 N less than or equal to lambda less than or equal to 21 0 N are reported. Preliminary estimates of neutron spectra were made

  4. The AME2003 atomic mass evaluation (I). Evaluation of input data, adjustment procedures

    International Nuclear Information System (INIS)

    Wapstra, A.H.; Audi, G.; Thibault, C.

    2003-01-01

    This paper is the first of two parts presenting the result of a new evaluation of atomic masses (AME2003). In this first part we give full information on the used and rejected input data and on the procedures used in deriving the tables in the second part. We first describe the philosophy and procedures used in selecting nuclear-reaction, decay, and mass spectrometric results as input values in a least-squares evaluation of best values for atomic masses. The calculation procedures and particularities of the AME are then described. All accepted data, and rejected ones with a reported precision still of interest, are presented in a table and compared there with the adjusted values. The differences with the earlier evaluation are briefly discussed and information is given of interest for the users of this AME. The second paper for the AME2003, last in this issue, gives a table of atomic masses, tables and graphs of derived quantities, and the list of references used in both this evaluation and the NUBASE2003 table (first paper in this issue). AMDC: http://csnwww.in2p3.fr/AMDC/

  5. THE DELTA UVRB MUTATIONS IN THE AMES STRAINS OF SALMONELLA SPAN 15-119 GENES

    Science.gov (United States)

    Abstract The 4uvrB mutationesent in strains of Salmonella enterica Typhirnurium used commonly in the Salmonella (Ames) mutagenicity assay were isolated independently on separate occasions: chl-1005 (bio uvrBgal) for the hisG46-containing strains TA1535 and TA100; chl- 10...

  6. Mutagenicity of anthraquinone and hydroxylated anthraquinones in the Ames/Salmonella microsome system.

    Science.gov (United States)

    Liberman, D F; Fink, R C; Schaefer, F L; Mulcahy, R J; Stark, A A

    1982-01-01

    The mutagenicity of anthracene, anthraquinone, and four structurally similar compounds of each was evaluated in the Ames/Salmonella microsome assay. Anthraquinone was shown to be mutagenic for strains TA1537, TA1538, and TA98 in the absence of rat liver homogenate. The four anthraquinone derivatives tested were mutagenic for TA1537 exclusively. None of the anthracenes exhibited mutagenic activity. PMID:7103489

  7. Mutagenicity of anthraquinone and hydroxylated anthraquinones in the Ames/Salmonella microsome system.

    OpenAIRE

    Liberman, D F; Fink, R C; Schaefer, F L; Mulcahy, R J; Stark, A A

    1982-01-01

    The mutagenicity of anthracene, anthraquinone, and four structurally similar compounds of each was evaluated in the Ames/Salmonella microsome assay. Anthraquinone was shown to be mutagenic for strains TA1537, TA1538, and TA98 in the absence of rat liver homogenate. The four anthraquinone derivatives tested were mutagenic for TA1537 exclusively. None of the anthracenes exhibited mutagenic activity.

  8. Evaluation of Genotoxicity of CSE1034 by Ames and In vitro ...

    African Journals Online (AJOL)

    Purpose: To evaluate the genotoxicity of CSE1034, a novel antibiotic adjuvant entity, using bacterial reverse mutation assay (Ames test) and in vitro chromosomal aberration test. Methods: Reverse mutation test was carried out using four strains of Salmonella typhimurium (TA 98, TA100, TA1535 and TA1537) and one strain ...

  9. The NASA Ames Polycyclic Aromatic Hydrocarbon Infrared Spectroscopic Database : The Computed Spectra

    NARCIS (Netherlands)

    Bauschlicher, C. W.; Boersma, C.; Ricca, A.; Mattioda, A. L.; Cami, J.; Peeters, E.; de Armas, F. Sanchez; Saborido, G. Puerta; Hudgins, D. M.; Allamandola, L. J.

    The astronomical emission features, formerly known as the unidentified infrared bands, are now commonly ascribed to polycyclic aromatic hydrocarbons (PAHs). The laboratory experiments and computational modeling done at the NASA Ames Research Center to create a collection of PAH IR spectra relevant

  10. Assaying the Mutagenic Potential of ELF Radiation through Reverse Mutagenesis via the Ames Test

    National Research Council Canada - National Science Library

    Moga, Paul

    1996-01-01

    ...) on certain strains of Salmonella typhimurium. The strain of S-typhimurium used in the Ames test has a mutation on one gene of the histidine operon which prevents it from growing and replicating without the presence of histidine in the media...

  11. Cultivating a Grassroots Aerospace Innovation Culture at NASA Ames Research Center

    Science.gov (United States)

    D'Souza, Sarah; Sanchez, Hugo; Lewis, Ryan

    2017-01-01

    This paper details the adaptation of specific 'knowledge production' methods to implement a first of its kind, grassroots event that provokes a cultural change in how the NASA Ames civil servant community engages in the creation and selection of innovative ideas. Historically, selection of innovative proposals at NASA Ames Research Center is done at the highest levels of management, isolating the views and perspectives of the larger civil servant community. Additionally, NASA innovation programs are typically open to technical organizations and do not engage non-technical organizations to bring forward innovative processes/business practices. Finally, collaboration on innovative ideas and associated solutions tend to be isolated to organizational silos. In this environment, not all Ames employees feel empowered to innovate and opportunities for employee collaboration are limited. In order to address these issues, the 'innovation contest' method was adapted to create the NASA Ames Innovation Fair, a unique, grassroots innovation opportunity for the civil servant community. The Innovation Fair consisted of a physical event with a virtual component. The physical event provided innovators the opportunity to collaborate and pitch their innovations to the NASA Ames community. The civil servant community then voted for the projects that they viewed as innovative and would contribute to NASA's core mission, making this event a truly grassroots effort. The Innovation Fair website provided a location for additional knowledge sharing, discussion, and voting. On March 3rd, 2016, the 'First Annual NASA Ames Innovation Fair' was held with 49 innovators and more than 300 participants collaborating and/or voting for the best innovations. Based on the voting results, seven projects were awarded seed funding for projects ranging from innovative cost models to innovations in aerospace technology. Surveys of both innovators and Fair participants show the Innovation Fair was successful

  12. Expression of oxidative phosphorylation components in mitochondria of long-living Ames dwarf mice.

    Science.gov (United States)

    Brown-Borg, Holly M; Johnson, W Thomas; Rakoczy, Sharlene G

    2012-02-01

    Reduced signaling of the growth hormone (GH)/insulin-like growth factor-1 (IGF-1) pathway is associated with extended life span in several species. Ames dwarf mice are GH-deficient and live >50% longer than wild-type littermates. Previously, we have shown that tissues from Ames mice exhibit elevated levels of antioxidative enzymes, less H(2)O(2) production, and lower oxidative damage suggesting that mitochondrial function may differ between genotypes. To explore the relationship between hormone deficiency and mitochondria in mice with extended longevity, we evaluated activity, protein, and gene expression of oxidative phosphorylation components in dwarf and wild-type mice at varying ages. Liver complex I + III activity was higher in dwarf mice compared to wild-type mice. The activity of I + III decreased between 3 and 20 months of age in both genotypes with greater declines in wild-type mice in liver and skeletal muscle. Complex IV activities in the kidney were elevated in 3- and 20-month-old dwarf mice relative to wild-type mice. In Ames mice, protein levels of the 39 kDa complex I subunit were elevated at 20 months of age when compared to wild-type mouse mitochondria for every tissue examined. Kidney and liver mitochondria from 20-month-old dwarf mice had elevated levels of both mitochondrially-encoded and nuclear-encoded complex IV proteins compared to wild-type mice (p dwarf mice. Overall, we found that several components of the oxidative phosphorylation (OXPHOS) system were elevated in Ames mice. Mitochondrial to nuclear DNA ratios were not different between genotypes despite the marked increase in PGC-1α levels in dwarf mice. The increased OXPHOS activities, along with lower ROS production in dwarf mice, predict enhanced mitochondrial function and efficiency, two factors likely contributing to long-life in Ames mice.

  13. Investigating the Mutagenic Effects of Three Commonly Used Pulpotomy Agents Using the Ames Test

    Science.gov (United States)

    Samiei, Mohammad; Asgary, Saeed; Farajzadeh, Malak; Bargahi, Nasrin; Abdolrahimi, Majid; Kananizadeh, Usef; Dastmalchi, Siavoush

    2015-01-01

    Purpose: The mutagenic potency of materials used in dentistry is of great concern. The Ames test is a bacterial reverse mutation assay, which is used to determine the mutagenicity potential of chemicals. In this study, the Ames test was used to compare mutagenic effects of three pulpotomy agents, namely, CEM cement, formocresol and ferric sulfate. Methods: TA100 strain of Salmonella typhimurium was used to evaluate mutagenicity of different concentrations of pulpotomy materials in the presence and absence of enzymatic system found in rat liver S9 fraction. Negative controls were 1% dimethyl sulfoxide and water. The positive controls were sodium azide and 2-aminoanthracene. The number of colonies per plate was counted. The material was regarded mutagenic if the number of histidine revertant colonies was twice or more than the spontaneous revertant colonies (Ames mutagenicity ratio). Results: Ferric sulfate was found mutagenic in the concentrations prepared by addition of 50 µL of its 1 in 100 and 1 in 1000 times diluted solutions to the culture medium in the absence of S9 fraction (Ames test ratios of 2.8 and 2.2, respectively). Formocresol showed strong toxicity toward TA100 strain of S. typhimurium up to the concentration as low achieved using 1000 times diluted solution of the original preparation, particularly in the presence of S9 fraction. Ames assay failed to detect significant reverse mutations in all the concentrations of CEM cement. Conclusion: In contrast to formocresol and ferric sulfate, CEM cement is a less toxic and non-mutagenic agent. PMID:25789229

  14. Investigating the Mutagenic Effects of Three Commonly Used Pulpotomy Agents Using the Ames Test

    Directory of Open Access Journals (Sweden)

    Mohammad Samiei

    2015-03-01

    Full Text Available Purpose: The mutagenic potency of materials used in dentistry is of great concern. The Ames test is a bacterial reverse mutation assay, which is used to determine the mutagenicity potential of chemicals. In this study, the Ames test was used to compare mutagenic effects of three pulpotomy agents, namely, CEM cement, formocresol and ferric sulfate. Methods: TA100 strain of Salmonella typhimurium was used to evaluate mutagenicity of different concentrations of pulpotomy materials in the presence and absence of enzymatic system found in rat liver S9 fraction. Negative controls were 1% dimethyl sulfoxide and water. The positive controls were sodium azide and 2-aminoanthracene. The number of colonies per plate was counted. The material was regarded mutagenic if the number of histidine revertant colonies was twice or more than the spontaneous revertant colonies (Ames mutagenicity ratio. Results: Ferric sulfate was found mutagenic in the concentrations prepared by addition of 50 μL of its 1 in 100 and 1 in 1000 times diluted solutions to the culture medium in the absence of S9 fraction (Ames test ratios of 2.8 and 2.2, respectively. Formocresol showed strong toxicity toward TA100 strain of S. typhimurium up to the concentration as low achieved using 1000 times diluted solution of the original preparation, particularly in the presence of S9 fraction. Ames assay failed to detect significant reverse mutations in all the concentrations of CEM cement. Conclusion: In contrast to formocresol and ferric sulfate, CEM cement is a less toxic and non-mutagenic agent.

  15. Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice.

    Science.gov (United States)

    Csiszar, Anna; Labinskyy, Nazar; Perez, Viviana; Recchia, Fabio A; Podlutsky, Andrej; Mukhopadhyay, Partha; Losonczy, Gyorgy; Pacher, Pal; Austad, Steven N; Bartke, Andrzej; Ungvari, Zoltan

    2008-11-01

    Hypopituitary Ames dwarf mice have low circulating growth hormone (GH)/IGF-I levels, and they have extended longevity and exhibit many symptoms of delayed aging. To elucidate the vascular consequences of Ames dwarfism we compared endothelial O2(-) and H2O2 production, mitochondrial reactive oxygen species (ROS) generation, expression of antioxidant enzymes, and nitric oxide (NO) production in aortas of Ames dwarf and wild-type control mice. In Ames dwarf aortas endothelial O2(-) and H2O2 production and ROS generation by mitochondria were enhanced compared with those in vessels of wild-type mice. In Ames dwarf aortas there was a less abundant expression of Mn-SOD, Cu,Zn-SOD, glutathione peroxidase (GPx)-1, and endothelial nitric oxide synthase (eNOS). NO production and acetylcholine-induced relaxation were also decreased in aortas of Ames dwarf mice. In cultured wild-type mouse aortas and in human coronary arterial endothelial cells treatment with GH and IGF significantly reduced cellular O2(-) and H2O2 production and ROS generation by mitochondria and upregulated expression of Mn-SOD, Cu,Zn-SOD, GPx-1, and eNOS. Thus GH and IGF-I promote antioxidant phenotypic changes in the endothelial cells, whereas Ames dwarfism leads to vascular oxidative stress.

  16. Next Generation Framework for Aquatic Modeling of the Earth System (NextFrAMES)

    Science.gov (United States)

    Fekete, B. M.; Wollheim, W. M.; Lakhankar, T.; Vorosmarty, C. J.

    2008-12-01

    Earth System model development is becoming an increasingly complex task. As scientists attempt to represent the physical and bio-geochemical processes and various feedback mechanisms in unprecedented detail, the models themselves are becoming increasingly complex. At the same time, the surrounding IT infrastructure needed to carry out these detailed model computations is growing increasingly complex as well. To be accurate and useful, Earth System models must manage a vast amount of data in heterogenous computing environments ranging from single CPU systems to Beowulf type computer clusters. Scientists developing Earth System models increasingly confront obstacles associated with IT infrastructure. Numerous development efforts are on the way to ease that burden and offer model development platforms that reduce IT challenges and allow scientists to focus on their science. While these new modeling frameworks (e.g. FMS, ESMF, CCA, OpenMI) do provide solutions to many IT challenges (performing input/output, managing space and time, establishing model coupling, etc.), they are still considerably complex and often have steep learning curves. Over the course of the last fifteen years ,the University of New Hampshire developed several modeling frameworks independently from the above-mentioned efforts (Data Assembler, Frameworks for Aquatic Modeling of the Earth System and NextFrAMES which is continued at CCNY). While the UNH modeling frameworks have numerous similarities to those developed by other teams, these frameworks, in particular the latest NextFrAMES, represent a novel model development paradigm. While other modeling frameworks focus on providing services to modelers to perform various tasks, NextFrAMES strives to hide all of those services and provide a new approach for modelers to express their scientific thoughts. From a scientific perspective, most models have two core elements: the overall model structure (defining the linkages between the simulated processes

  17. Aerial radiological survey of US Department of Energy sites in Ames, Iowa. Date of survey: May 1977

    International Nuclear Information System (INIS)

    1979-07-01

    An aerial radiological survey to measure terrestrial gamma radiation was carried out over five areas totaling 10 km 2 within the town of Ames, Iowa. Gamma ray data were measured over Ames Laboratory, several sections of downtown Ames, and the surrounding area. This was accomplished by flying parallel east-west lines 61 m apart. Processed data indicated that three areas showed increased activity levels of at least twice average background: the reactor, the waste treatment area, and a small area near the airport runway

  18. Long-lived ames dwarf mice are resistant to chemical stressors.

    Science.gov (United States)

    Bokov, Alex F; Lindsey, Merry L; Khodr, Christina; Sabia, Marian R; Richardson, Arlan

    2009-08-01

    To probe the connection between longevity and stress resistance, we compared the sensitivity of Ames long-lived dwarf mice and control littermates with paraquat, diquat, and dobutamine. In young adult animals, 95% of male and 39% of female controls died after paraquat administration, but no dwarf animals died. When the experiment was repeated at an older age or a higher dosage of paraquat, dwarf mice still showed greater resistance. Dwarf mice also were more resistant to diquat; 80% of male and 60% of female controls died compared with 40% and 20% of dwarf mice, despite greater sensitivity of dwarf liver to diquat. Dwarf mice were also less sensitive to dobutamine-induced cardiac stress and had lower levels of liver and lung F(2)-isoprostanes. This is the first direct in vivo evidence that long-lived Ames dwarf mice have enhanced resistance to chemical insult, particularly oxidative stressors.

  19. The NASA Ames Life Sciences Data Archive: Biobanking for the Final Frontier

    Science.gov (United States)

    Rask, Jon; Chakravarty, Kaushik; French, Alison J.; Choi, Sungshin; Stewart, Helen J.

    2017-01-01

    The NASA Ames Institutional Scientific Collection involves the Ames Life Sciences Data Archive (ALSDA) and a biospecimen repository, which are responsible for archiving information and non-human biospecimens collected from spaceflight and matching ground control experiments. The ALSDA also manages a biospecimen sharing program, performs curation and long-term storage operations, and facilitates distribution of biospecimens for research purposes via a public website (https:lsda.jsc.nasa.gov). As part of our best practices, a tissue viability testing plan has been developed for the repository, which will assess the quality of samples subjected to long-term storage. We expect that the test results will confirm usability of the samples, enable broader science community interest, and verify operational efficiency of the archives. This work will also support NASA open science initiatives and guides development of NASA directives and policy for curation of biological collections.

  20. Collective effects in Au(100-800 AMeV) + Au semi-central collisions

    International Nuclear Information System (INIS)

    Crochet, P.

    1996-01-01

    The present work has been carried out in the framework of the experimental program of the FOPI collaboration. It is devoted to a systematic study of the different forms of collective expansion of nuclear matter in semi-central Au+Au collisions at incident energies ranging from 100 AMeV to 800 AMeV. The aim is to investigate the influence of compressional effects, momentum dependence of the nuclear interaction and nucleon-nucleon cross section on the observed phenomena. Important changes in the reaction mechanisms are evidenced, in particular at low incident energies where one observes, on the one hand, a transition from an enhanced in-plane emission to a preferential out-of-plane emission pattern and, on the other hand, a strong reduction of the directed in-plane component. Experimental results are compared to the predictions of the Quantum Molecular Dynamics (QMD) model for different parametrizations of the nuclear interaction. (author)

  1. Study of optical techniques for the Ames unitary wind tunnel: Digital image processing, part 6

    Science.gov (United States)

    Lee, George

    1993-01-01

    A survey of digital image processing techniques and processing systems for aerodynamic images has been conducted. These images covered many types of flows and were generated by many types of flow diagnostics. These include laser vapor screens, infrared cameras, laser holographic interferometry, Schlieren, and luminescent paints. Some general digital image processing systems, imaging networks, optical sensors, and image computing chips were briefly reviewed. Possible digital imaging network systems for the Ames Unitary Wind Tunnel were explored.

  2. Mutagenic Potential of Physostigmine Salicylate in the Ames Salmonella/ Mammalian Microsome Mutagenicity Test

    Science.gov (United States)

    1988-12-01

    Molecular Weight: 413.47 Analytical Data: The test compound was analyzed by the sponsors and the identity confirmed by UV and IR spectroscopy , high pressure...AD-A203 802 Institute Report No. 320 Mutagenic Potential of Physostigmine Salicylate in the Ames Salmonella/Mammalian Microsome Mutagenicity Test...T%&)MS (Continue on reverse if necessary and identify by block number) FiELDI GROUP ISUB-GROUP Physostigmine Salicylate , Mutagenicity, Genetic

  3. An aerodynamic performance evaluation of the NASA/Ames Research Center Advanced Concepts Flight Simulator

    OpenAIRE

    Donohue, Paul F.

    1987-01-01

    Approved for public release; distribution is unlimited The results of an aerodynamic performance evaluation of the National Aeronautics and Space Administration (NASA)/Ames Research Center Advanced Concepts Flight Simulator (ACFS), conducted in association with the Navy-NASA Joint Institute of Aeronautics, are presented. The ACFS is a full-mission flight simulator which provides an excellent platform for the critical evaluation of emerging flight system and aircrew performance. The propu...

  4. Microplate Ames MPF™ test use in assessment of mutagenic properties of dust pollution

    Directory of Open Access Journals (Sweden)

    Agnieszka Kozłowska

    2012-09-01

    Full Text Available Background: Highly industrialized Upper Silesia Region is particularly polluted by both anthropogenic and natural airborne particulate matters, which may lead to negative health effects in human. Materials and methods: The aim of the study was to assess the mutagenic properties of dust extracts which were collected in six cities in the Silesian Voivodeship. Dust samples were collected on glass fiber filters by the aspirator with air flow ca. 1 m3/min. Extraction of pollution was carried out using dichlorometane. The extracted samples were dissolved in dimethylsulfoxide (DMSO. The mutagenic properties were assessed using microplate Ames assay MPFTM with the use of bacteria Salmonella typhimurium strain TA98 and TA100. Results: In microplate Ames assay MPFTM there was observed a linear dose-response relationship in both metabolic variants of TA98 strain. Similar relationship was observed for TA100 strain with metabolic activation (S9. Mutagenic activity (AM of 100% extracts for TA98 strain in both metabolic variants (S9 exceeded 2, what indicate highly mutagenic effects of dust extracts. There was no mutagenic activity observed in the assay with TA100 (S9, AM 1. In the variant with exogenous metabolic activation (S9 in TA100 strain AM values ranged from AM1,160,15 to AM9,671,02. Mutagenic activity varied between different cities. Conclusions: The study demonstrated that microplate Ames assay MPFTM is fast and complex method of assessing the mutagenic properties of dust pollution, which exert toxic effect on organisms. The use of microplate Ames assay MPFTM together with chemical analyses of air dust pollution may evaluate the level of exposure in the environment and enable to perform health risk assessment in populations exposed to mutagenic, toxic and cytotoxic substances.

  5. Study of optical techniques for the Ames unitary wind tunnel. Part 5: Infrared imagery

    Science.gov (United States)

    Lee, George

    1992-01-01

    A survey of infrared thermography for aerodynamics was made. Particular attention was paid to boundary layer transition detection. IR thermography flow visualization of 2-D and 3-D separation was surveyed. Heat transfer measurements and surface temperature measurements were also covered. Comparisons of several commercial IR cameras were made. The use of a recently purchased IR camera in the Ames Unitary Plan Wind Tunnels was studied. Optical access for these facilities and the methods to scan typical models was investigated.

  6. 2-Hydroxypyridine-N-oxide (HOPO): Equivocal in the ames assay.

    Science.gov (United States)

    Dobo, Krista L; Cheung, Jennifer R; Gunther, William C; Kenyon, Michelle O

    2018-05-01

    2-Hydroxypyridine-N-oxide (HOPO) is a useful coupling reagent for synthesis of active pharmaceutical ingredients. It has been reported to be weakly mutagenic in the Ames assay (Ding W et al. []: J Chromatogr A 1386:47-52). According to the ICH M7 guidance (2014) regarding control of mutagenic impurities to limit potential carcinogenic risk, mutagens require control in drug substances such that exposure not exceeds the threshold of toxicological concern. Given the weak response observed in the Ames assay and the lack of any obvious structural features that could confer DNA reactivity we were interested to determine if the results were reproducible and investigate the role of potentially confounding experimental parameters. Specifically, Ames tests were conducted to assess the influence of compound purity, solvent choice, dose spacing, toxicity, type of S9 (aroclor vs phenobarbital/β-napthoflavone), and lot variability on the frequency of HOPO induced revertant colonies. Initial extensive testing using one lot of HOPO produced no evidence of mutagenic potential in the Ames assays. Subsequent studies with four additional lots produced conflicting results, with an ∼2.0-fold increase in revertant colonies observed. Given the rigor of the current investigation, lack of reproducibility between lots, and the weak increase in revertants, it is concluded that HOPO is equivocal in the bacterial reverse mutation assay. It is highly unlikely that HOPO poses a mutagenic risk in vivo; therefore, when it is used as a reagent in pharmaceutical synthesis, it should not be regarded as a mutagenic impurity, but rather a normal process related impurity. Environ. Mol. Mutagen. 59:312-321, 2018. © 2018 Wiley Periodicals, Inc. © 2018 Wiley Periodicals, Inc.

  7. Ameli-EAUR project: which lessons for the promotion of agricultural value chains?

    Science.gov (United States)

    Traoré, M. B.; Dakouré, M. S.; Maïga, A. H.

    2017-03-01

    Due to the lack of rain, dry spell and agricultural insufficient inputs, agricultural yields are very low and do not allow achieving food self-sufficiency in countries such as Burkina Faso. To fight against this situation in the context of climate change, several researches have emerged such as agronomic research with the promotion of crop varieties that require little water and short growth period. The Ameli-EAUR project is another example of research. This project aimed to promote hygiene and sanitation by the use of sanitation by-product in rural and sub-urban areas of Burkina Faso. Ameli-EAUR project was initiated and implemented within five years. Completed in 2015, it appears necessary to think over its impacts on production hence the question: which lessons for the promotion of agriculture, specifically for agricultural value chains“? Based on the result of a post-survey performed one year after the end of the project, the aim of this presentation is to show that project can support the promotion of agricultural Value Chains in spite of difficulties if we take into account some parameters. To do this, we will start by presenting briefly Ameli-EAUR; then we will take stock of the project; finally, we will examine the possibilities it offers for the promotion of agricultural value chains, taking as example the vegetable gardening. We will also try to show the limits of value chains which are presented nowadays as a solution to many problems of agriculture in Africa.

  8. A mutagenicity and cytotoxicity study of limonium effusum aqueous extracts by Allium, Ames and MTT tests.

    Science.gov (United States)

    Eren, Y; Ozata, A; Konuk, M; Akyil, D; Liman, R

    2015-01-01

    Nowadays plants or plant extracts have become very important for alternative medicine. Plants and their extracts have many therapeutical advantages but some of them are potentially toxic, mutagenic, carcinogenic and teratogenic. Root, stem and leafparts of Limonium effusum were used in this study and this species is an endemic species for Turkey. Mutagenic and cytotoxic effects of root, stem and leaf aqueous extracts were observed with Allium, Ames and MTT tests. Allium root growth inhibition test and mitotic index studies showed that aqueous extracts have dose-dependent toxic effects. Chromosome aberration studies indicated that especially sticky chromosome, anaphase-telophase disorder and laggard chromosome anomalies were highly observed. Ames test performed with Limonium effusum root aqueous extracts, showed weak mutagenic effects in Salmonella typhimurium TA98 strain with S9. MTT test based on mitochondrial activity indicated that most of the aqueous extracts have cytotoxic effects. This study aimed to determine the possible mutagenic and cytotoxic effects of L. effusum aqueous extracts by using bacterial, plant and mammalian cells. This research showed that some low concentrations of the L. effusum extracts have inhibited cytotoxic effects but high concentrations have induced cytotoxicity. On the other hand only a weak mutagenic activity was identified by Ames test with TA98 S9(+).

  9. NASA Ames DEVELOP Interns: Helping the Western United States Manage Natural Resources One Project at a Time

    Science.gov (United States)

    Justice, Erin; Newcomer, Michelle

    2010-01-01

    The western half of the United States is made up of a number of diverse ecosystems ranging from arid desert to coastal wetlands and rugged forests. Every summer for the past 7 years students ranging from high school to graduate level gather at NASA Ames Research Center (ARC) as part of the DEVELOP Internship Program. Under the guidance of Jay Skiles [Ames Research Center (ARC) - Ames DEVELOP Manager] and Cindy Schmidt [ARC/San Jose State University Ames DEVELOP Coordinator] they work as a team on projects exploring topics including: invasive species, carbon flux, wetland restoration, air quality monitoring, storm visualizations, and forest fires. The study areas for these projects have been in Washington, Utah, Oregon, Nevada, Hawaii, Alaska and California. Interns combine data from NASA and partner satellites with models and in situ measurements to complete prototype projects demonstrating how NASA data and resources can help communities tackle their Earth Science related problems.

  10. Rotor Performance of a UH-60 Rotor System in the NASA Ames 80- by 120-Foot Wind Tunnel

    National Research Council Canada - National Science Library

    Shinoda, Patrick M; Yeo, Hyeonsoo; Norman, Thomas R

    2002-01-01

    .... To evaluate the NASA Ames 80- by 120- Foot Wind Tunnel as a hover testing facility, rotor performance data were compared with predictions, UH-60 aircraft flight test data, and UH-60 model-scale data...

  11. State of the Art High-Throughput Approaches to Genotoxicity: Flow Micronucleus, Ames II, GreenScreen and Comet

    Science.gov (United States)

    State of the Art High-Throughput Approaches to Genotoxicity: Flow Micronucleus, Ames II, GreenScreen and Comet (Presented by Dr. Marilyn J. Aardema, Chief Scientific Advisor, Toxicology, Dr. Leon Stankowski, et. al. (6/28/2012)

  12. The NASA Ames Hypervelocity Free Flight Aerodynamic Facility: Experimental Simulation of the Atmospheric Break-Up of Meteors

    Science.gov (United States)

    Wilder, M. C.; Bogdanoff, D. W.

    2015-01-01

    The Hypervelocity Free Flight Aerodynamic Facility at NASA Ames Research Center provides a potential platform for the experimental simulation of meteor breakup at conditions that closely match full-scale entry condition for select parameters. The poster describes the entry environment simulation capabilities of the Hypervelocity Free Flight Aerodynamic Facility (HFFAF) at NASA Ames Research Center and provides example images of the fragmentation of a hypersonic projectile for which break-up was initiated by mechanical forces (impact with a thin polymer diaphragm).

  13. Examination of Alternaria alternata mutagenicity and effects of nitrosylation using the Ames Salmonella test.

    Science.gov (United States)

    Schrader, T J; Cherry, W; Soper, K; Langlois, I; Vijay, H M

    2001-01-01

    Molds of the genus Alternaria are common food pathogens responsible for the spoilage of fruits, vegetables, grains, and nuts. Although consumption of Alternaria alternata-contaminated foodstuffs has been implicated in an elevated incidence of esophageal carcinogenesis, the mutagenic potencies of several A. alternata toxins seem unable to account for the levels of activity found using crude mycelial extracts. In this study, the mutagenic effects of nitrosylation were examined with the major Alternaria metabolites Altenuene (ALT), Alternariol (AOH), Alternariol Monomethyl Ether (AME), Altertoxin I (ATX I), Tentoxin (TENT), Tenuazonic Acid (TA), and Radicinin (RAD) using the Ames Salmonella strains TA98 and TA100. In the absence of nitrosylation, ATX I was mutagenic when tested from 1 to 100 microg/plate in TA98 with rat liver S9 for activation, while AOH and ATX I were weakly mutagenic +/- S9 in TA100. Incubation with nitrite generally increased mutagenic potencies with ATX I strongly mutagenic +/- S9 in both TA98 and TA100, while ALT, AOH, AME, and RAD responses were enhanced in TA100 + S9. However, subsequent examination of three extracts made from A. alternata culture broth, acetone-washed mycelia, and the acetone washes showed a different mutagenic response with both broth and acetone washes directly mutagenic in TA98 and TA100 but with a reduced response + S9. The acetone-washed mycelial extract was found to have the lowest mutagenic activity of the three extracts tested. Nitrosylation had little effect on the mutagenicity of any of the extracts. Thus, while nitrosylation increases the mutagenicity of ATX I, and to a lesser extent that of several other Alternaria toxins, the results demonstrate that Alternaria produces a major mutagenic activity with a S. typhimurium response different from that found with the purified toxins. Efforts are currently underway to chemically identify this mutagenic species. Published 2001 Wiley-Liss, Inc.

  14. Feature combination networks for the interpretation of statistical machine learning models: application to Ames mutagenicity.

    Science.gov (United States)

    Webb, Samuel J; Hanser, Thierry; Howlin, Brendan; Krause, Paul; Vessey, Jonathan D

    2014-03-25

    A new algorithm has been developed to enable the interpretation of black box models. The developed algorithm is agnostic to learning algorithm and open to all structural based descriptors such as fragments, keys and hashed fingerprints. The algorithm has provided meaningful interpretation of Ames mutagenicity predictions from both random forest and support vector machine models built on a variety of structural fingerprints.A fragmentation algorithm is utilised to investigate the model's behaviour on specific substructures present in the query. An output is formulated summarising causes of activation and deactivation. The algorithm is able to identify multiple causes of activation or deactivation in addition to identifying localised deactivations where the prediction for the query is active overall. No loss in performance is seen as there is no change in the prediction; the interpretation is produced directly on the model's behaviour for the specific query. Models have been built using multiple learning algorithms including support vector machine and random forest. The models were built on public Ames mutagenicity data and a variety of fingerprint descriptors were used. These models produced a good performance in both internal and external validation with accuracies around 82%. The models were used to evaluate the interpretation algorithm. Interpretation was revealed that links closely with understood mechanisms for Ames mutagenicity. This methodology allows for a greater utilisation of the predictions made by black box models and can expedite further study based on the output for a (quantitative) structure activity model. Additionally the algorithm could be utilised for chemical dataset investigation and knowledge extraction/human SAR development.

  15. Urine recovery experiments with quercetin and other mutagens using the Ames test

    Energy Technology Data Exchange (ETDEWEB)

    Busch, D.B.; Hatcher, J.F.; Bryan, G.T.

    1986-01-01

    Recovery from urine of the mutagenic activity of 2-anthramine, cyclophosphamide, 7,12-dimethylbenz(a)anthracene, 6-chloro-9-((3-(2-chloroethylamino)-propyl)amino)-2-methoxyacridine dihydrochloride (ICR-191), mitomycin-C, nitrofurantoin, and quercetin was studied with several of the Ames tester strains using acetone-extracted XAD-2 columns with yields ranging from 27% to 79%. Dose responses of the pure chemicals were also studied, and results showed TA 97 to be far more susceptible to quercetin mutagenesis than TA 1537. Reducing pour plate agar volume enhanced mutagenesis.

  16. Exploration of a steamship wreck off Amee shoals, Goa, India: A preliminary report

    Digital Repository Service at National Institute of Oceanography (India)

    Tripati, S.; Gaur, A.S.; Sundaresh

    suggest that the wreck dates to the 19th century AD, and is the first wreck of the Basel Mission Company to be located (Sila Tripati et al., 2003). The site and its location Amee shoals lie off Marmagao Bay, to the south of Sunchi Reef, dividing... to 1880 or later. By the 20th century, with the use of higher pressures, more modern designs replaced the simple boiler. As one example of vessels of this type deployed in this region, during the Portuguese regime in Goa, a British company was tasked...

  17. An evaluation of instant and regular coffee in the Ames mutagenicity test.

    Science.gov (United States)

    Aeschbacher, H U; Würzner, H P

    1980-02-01

    High concentrations of "home brew" and instant coffe induced revertants 2--3-fold the spontaneous level with the Ames Salmonella tester strain TA 100 but not with the strains TA 98, TA 1535, TA 1537 and TA 1538. This borderline effect, which may also have been due to non-mutagenic interactions (false positives) occurred only at bacterial levels of coffees and was completely abolished in the presence of the microsomal "metabolic activation system". Negative results were obtained in host-mediated assays when mice received up to 6 g instant coffee/kg body weight. An extrapolation in respect of possible carcinogenic risks is dubious.

  18. Investigating the Source of Planck-Detected AME: High-Resolution Observations at 15 GHz

    Directory of Open Access Journals (Sweden)

    Yvette C. Perrott

    2013-01-01

    Full Text Available The Planck 28.5 GHz maps were searched for potential Anomalous Microwave Emission (AME regions on the scale of ~3° or smaller, and several new regions of interest were selected. Ancillary data at both lower and higher frequencies were used to construct spectral energy distributions (SEDs, which seem to confirm an excess consistent with spinning dust models. Here we present higher resolution observations of two of these new regions with the Arcminute Microkelvin Imager Small Array (AMI SA between 14 and 18 GHz to test for the presence of a compact (~10 arcmin or smaller component. For AME-G107.1+5.2, dominated by the Hii region S140, we find evidence for the characteristic rising spectrum associated with either the spinning dust mechanism for AME or an ultra- /hypercompact Hii region across the AMI frequency band; however, for AME-G173.6+208 we find no evidence for AME on scales of ~2–10 arcmin.

  19. Ames Mutagenicity Assessment of Flavored Water Pipe Tobacco Products :A Cross Sectional Study in Tehran

    Directory of Open Access Journals (Sweden)

    Shahrzad Sadri

    2016-12-01

    Full Text Available Waterpipe smoking has become a global youth trend especially in the Middle East countries and Iran . The aim of this study was to determine the mutagenic effects of three most popular flavored tobaccos by four different salmonella typhimurium strains and compare the possible mutagenic effects of the test samples. Ames mutagenicity assessment was conducted according to the OECD guideline using TA100, TA98 , YG1024 and YG1029 strains. Charcoal burned flavored tobaccos of three different flavors including Orange, Double Apple, and Lime Mint were filtered and exposed to all strains after strain identification tests and MIC ,MBC determinations. The Ames test results indicated significant mutagenic effects of tobacco samples in all four test strains when compared with negative control (p≤0.0001. The highest Mutagenic Factor (MF was seen in Double Apple samples using TA 98 (MF=11.5±3.3 . In all experiments, TA strains showed higher sensitivity to the samples than YG strains which suggest these two strains for further regulatory toxicity tests ,policy making purposes and tobacco control programs . Present results represents an important step in understanding the genotoxic potentials of three most popular flavored tobaccos samples of a famous brand in the global markets .

  20. [Preclinical AD and Biomarker; from J-ADNI to AMED Preclinical Study].

    Science.gov (United States)

    Suzuki, Kazushi

    2017-07-01

    Alzheimer's disease (AD) is most prevalent cause of dementia and no cure has been discovered. Although the framework of AD clinical trials is being established utilizing results of large-scale observational studies such as the AD Neuroimaging Initiative (ADNI) and the Japanese-ADNI (J-ADNI), the development of disease-modifying therapy for Alzheimer's disease (AD) has not yet been achieved. Preclinical AD was recently defined as a new disease stage in which AD is asymptomatic but biomarkers suggest the presence of amyloid pathology. Preclinical AD has been focused as promising therapeutic time window and establishment of reliable biomarkers for preclinical AD is an urgent task. The Japanese Agency for Medical Research and Development (AMED) preclinical study is a nationwide multicenter observational study carried out by public research funding from AMED as a successor to the J-ADNI study. The goal of this study is to establish a biomarker that can quantitatively evaluate the disease progression of preclinical AD and mild cognitive impairment (MCI) or predict the progression to MCI and dementia in the future. To achieve this goal, the following assessments will be conducted over time for three years: clinical evaluations; cognitive tests; genetic testing; body fluid biomarker tests; and imaging biomarker studies such as MRI, FDG-PET, and amyloid PET. The obtained data will eventually be released to the public database.

  1. Thyroxine modifies the effects of growth hormone in Ames dwarf mice.

    Science.gov (United States)

    Do, Andrew; Menon, Vinal; Zhi, Xu; Gesing, Adam; Wiesenborn, Denise S; Spong, Adam; Sun, Liou; Bartke, Andrzej; Masternak, Michal M

    2015-04-01

    Ames dwarf (df/df) mice lack growth hormone (GH), thyroid stimulating hormone and prolactin. Treatment of juvenile df/df mice with GH alone stimulates somatic growth, reduces insulin sensitivity and shortens lifespan. Early-life treatment with thyroxine (T4) alone produces modest growth stimulation but does not affect longevity. In this study, we examined the effects of treatment of juvenile Ames dwarf mice with a combination of GH + T4 and compared them to the effects of GH alone. Treatment of female and male dwarfs with GH + T4 between the ages of 2 and 8 weeks rescued somatic growth yet did not reduce lifespan to match normal controls, thus contrasting with the previously reported effects of GH alone. While the male dwarf GH + T4 treatment group had no significant effect on lifespan, the female dwarfs undergoing treatment showed a decrease in maximal longevity. Expression of genes related to GH and insulin signaling in the skeletal muscle and white adipose tissue (WAT) of female dwarfs was differentially affected by treatment with GH + T4 vs. GH alone. Differences in the effects of GH + T4 vs. GH alone on insulin target tissues may contribute to the differential effects of these treatments on longevity.

  2. Genotoxic and cytotoxic potential of whole plant extracts of Kalanchoe laciniata by Ames and MTT assay.

    Science.gov (United States)

    Sharif, Ali; Akhtar, Muhammad Furqan; Akhtar, Bushra; Saleem, Ammara; Manan, Maria; Shabbir, Maryam; Ashraf, Muneeb; Peerzada, Sohaib; Ahmed, Shoaib; Raza, Moosa

    2017-01-01

    Lack of data on safety of herbal medicines have endangered human health and life. The present study evaluated the genotoxic and mutagenic effect of Kalanchoe laciniata to access the safety and usefulness of the medicinal plant. Aqua-methanolic and n-hexane extracts of K. laciniata were evaluated for the genotoxic potential using Ames assay and cytotoxicity was evaluated using MTT assay. Ames assay was conducted using two strains of Salmonella typhimurium TA-100 and TA-102 whereas MTT assay was performed on baby hamster kidney cell line BHK-21. Aqua-methanolic extract of K. laciniata exhibited significant mutagenicity when exposed to TA-102 strain with a mutagenic index of 50.66 and 54.74 at maximum dose 150 mg/plate. The extract was also mutagenic to TA-100 strain but to a lesser extent. M.I of n-hexane extract was 12.15 and 15.51 for TA-100 and TA-102 respectively. n-hexane extract was mutagenic but little difference was observed between results of two strains. Both extracts were found to be cytotoxic with an IC 50 of 321.9 and 638.5 µg/mL for aqua-methanolic and n-hexane extracts respectively. On the basis of results it was concluded that aqua-methanolic and n-hexane extracts of K. laciniata possess mutagenic and cytotoxic potential. It is suggested to explore the plant further to evaluate its safety in rodents and other species.

  3. Are effects of common ragwort in the Ames test caused by pyrrolizidine alkaloids?

    Science.gov (United States)

    Bovee, Toine F H; Helsdingen, Richard J R; Hoogenboom, Ron L A P; de Nijs, Monique W C M; Liu, Xiaojie; Vrieling, Klaas; Klinkhamer, Peter G L; Peijnenburg, Ad A C M; Mulder, Patrick P J

    2015-08-01

    It has previously been demonstrated by others that acetone extracts of Senecio jacobaea (syn. Jacobaea vulgaris, common or tansy ragwort) test positive in the Salmonella/microsome mutagenicity test (Ames test). Pyrrolizidine alkaloids (PAs) are thought to be responsible for these mutagenic effects. However, it was also observed that the major PA present in common ragwort, jacobine, produced a negative response (with and without the addition of rat liver S9) in Salmonella test strains TA98, TA100, TA1535 and TA1537. To investigate which compounds in the plant extracts were responsible for the positive outcome, the present study investigated the contents and mutagenic effects of methanol and acetone extracts prepared from dried ground S. jacobaea and Senecio inaequidens (narrow-leafed ragwort). Subsequently, a fractionation approach was set up in combination with LC-MS/MS analysis of the fractions. It was shown that the positive Ames test outcomes of S. jacobaea extracts are unlikely to be caused by PAs, but rather by the flavonoid quercetin. This study also demonstrates the importance of identifying compounds responsible for positive test results in bioassays. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Mutagenicity and antimutagenicity of six Brazilian Byrsonima species assessed by the Ames test.

    Science.gov (United States)

    Espanha, Lívia Greghi; Resende, Flávia Aparecida; de Sousa Lima Neto, José; Boldrin, Paula Karina; Nogueira, Catarine Haidê; de Camargo, Mariana Santoro; De Grandis, Rone Aparecido; dos Santos, Lourdes Campaner; Vilegas, Wagner; Varanda, Eliana Aparecida

    2014-06-05

    In various regions of Brazil, several species of the genus Byrsonima (Malpighiaceae) are widely used to treat gastrointestinal complications. This genus has about 150 species of shrubs and trees distributed over the entire Neotropical region. Various biological activities have been identified in these plants, especially antioxidant, antimicrobial and topical and systemic anti-inflammatory activities. The aim of this study was to investigate the mutagenicity and antimutagenicity of hydroalcoholic leaf extracts of six species of Byrsonima: B. verbascifolia, B. correifolia, B. coccolobifolia, B. ligustrifolia, B. fagifolia and B. intermedia by the Salmonella microsome assay (Ames test). Mutagenic and antimutagenic activity was assessed by the Ames test, with the Salmonella typhimurium tester strains TA100, TA98, TA97a and TA102, with (+S9) and without (-S9) metabolization, by the preincubation method. Only B. coccolobifolia and B. ligustrifolia showed mutagenic activity. However, the extracts of B. verbascifolia, B. correifolia, B. fagifolia and B. intermedia were found to be strongly antimutagenic against at least one of the mutagens tested. These results contribute to valuable data on the safe use of medicinal plants and their potential chemopreventive effects. Considering the excellent antimutagenic activities extracted from B. verbascifolia, B. correifolia, B. fagifolia and B. intermedia, these extracts are good candidate sources of chemopreventive agents. However, B. coccolobifolia and B. ligustrifolia showed mutagenic activity, suggesting caution in their use.

  5. Assessment of diphenylcyclopropenone for photochemically induced mutagenicity in the Ames assay

    Energy Technology Data Exchange (ETDEWEB)

    Wilkerson, M.G.; Connor, T.H.; Henkin, J.; Wilkin, J.K.; Matney, T.S.

    1987-10-01

    The photochemical conversion of diphenylcyclopropenone to diphenylacetylene has recently been reported. Diphenylcyclopropenone is used in the treatment of alopecia areata and is nonmutagenic in a limited Ames assay. We examined diphenylcyclopropenone and diphenylacetylene, as well as synthetic precursors of diphenylcyclopropenone--dibenzylketone and alpha,alpha'-dibromodibenzylketone--for mutagenicity against TA100, TA98, TA102, UTH8413, and UTH8414. All compounds were nonmutagenic except alpha,alpha'-dibromodibenzylketone, which was a potent mutagen in TA100 with and without S-9 activation. The effect of photochemical activation of diphenylcyclopropenone in the presence of bacteria demonstrated mutagenicity in UTH8413 (two times background) at 10 micrograms/plate with S-9 microsomal activation. 8-Methoxypsoralen produces a mutagenic response in TA102 at 0.1 microgram/plate with 60 seconds of exposure to 350 nm light. In vitro photochemically activated Ames assay with S-9 microsomal fraction may enhance the trapping of short-lived photochemically produced high-energy mutagenic intermediates. This technique offers exciting opportunities to trap high-energy intermediates that may play an important role in mutagenesis. This method can be applied to a variety of topically applied dermatologic agents, potentially subjected to photochemical changes in normal use.

  6. New NASA-Ames wind-tunnel techniques for studying airplane spin and two-dimensional unsteady aerodynamics

    Science.gov (United States)

    Malcolm, G. N.; Davis, S. S.

    1978-01-01

    Two new wind tunnel test apparatuses were developed at NASA-Ames Research Center. The first is a rotary-balance apparatus to be used in the Ames 12-Foot Pressure Tunnel for investigating the effects of Reynolds number, spin rate, and angle of attack on the aerodynamics of fighter and general aviation aircraft in a steady spin motion. The second apparatus provides capability for oscillating a large two dimensional wing (0.5 m chord, 1.35 m span) instrumented with steady and unsteady pressure transducers in the Ames 11 x 11 ft. Transonic Wind Tunnel. A complete description of both apparatuses, their capabilities, and some typical wind tunnel results are presented.

  7. Investigating the intra-nuclear cascade process using the reaction 136Xe on deuterium at 500 AMeV

    Directory of Open Access Journals (Sweden)

    Rejmund F.

    2010-10-01

    Full Text Available More than 600 residual nuclei, formed in the spallation of 136Xe projectiles impinging on deuterium at 500 AMeV of incident energy, have been unambiguously identified and their production cross sections have been determined with high accuracy. By comparing these data to others previously measured for the reactions 136Xe  +  p at 1 AGeV and 136Xe  +  p at 500 AMeV we investigated the role that neutrons play in peripheral collisions and to understand the energy dissipation in frontal collisions in spallation reactions.

  8. EA Annex XX. Comparison between calculations and measurements on a wind turbine in the NASA-Ames wind tunnel

    Energy Technology Data Exchange (ETDEWEB)

    Schepers, J.G. [ECN Wind Energy, Petten (Netherlands)

    2007-11-15

    This report describes a study in which calculational results from ECN's aeroelastic code PHATAS and the free wake lifting line code AWSM are compared with wind tunnel measurements which were carried out by NREL on a wind turbine, placed in the large NASA-Ames wind tunnel. Measurements have been taken at a large variety of conditions but in this report data at non-yawed conditions are considered only. The study was carried out within the framework IEA Annex XX 'Analysis of NASA-Ames windtunnel measurements'.

  9. The Use of the Ames Test as a Tool for Addressing Problem-Based Learning in the Microbiology Lab

    Directory of Open Access Journals (Sweden)

    Eliana Rodríguez

    2012-08-01

    Full Text Available Our environment is full of potential carcinogens such as UV light, industrial pollutants, pesticides, and food additives, among others. It is estimated that 90% of all carcinogens are also mutagens. The Ames test is one of the most common tests for mutagens. In this problem-based learning activity, undergraduate biology students used the Ames test to screen a substance they provided, to see if it could be considered a mutagen. The idea of surveying substances used in everyday life appealed to our students, and helped engage them in this activity.

  10. Isolation and genotyping of Acanthamoeba spp. from Acanthamoeba meningitis/ meningoencephalitis (AME) patients in India.

    Science.gov (United States)

    Behera, Himanshu Sekhar; Satpathy, Gita; Tripathi, Manjari

    2016-08-09

    Acanthamoeba spp. are free-living ubiquitous protozoans capable of causing Acanthamoeba meningitis/meningoencephalitis (AME) of the central nervous system in humans. Acanthamoeba spp. are divided into 20 different genotypes (T1-T20) on the basis of variation in nucleotide sequences of the 18S rRNA gene. The objective of this study was to identify the genotypes of Acanthamoeba spp. in patients of Acanthamoeba meningitis/meningoencephalitis (AME) using 18S rRNA gene-based PCR assay. The present study provides information regarding the involvement of the most prevalent and predominant genotype of Acanthamoeba spp. in Acanthamoeba meningitis/meningoencephalitis infections in India. Cerebrospinal fluid (CSF) was collected from 149 clinically suspected Acanthamoeba meningitis/meningoencephalitis (AME) patients reporting to the outpatient department/causality services of the Neurosciences Centre, AIIMS, New Delhi, India during the past five years. Samples were inoculated onto 2 % non-nutrient agar plates overlaid with E. coli and incubated at 30 °C for 14 days. Among 149 suspected patients, ten were found culture-positive for Acanthamoeba spp. out of which six isolates were established in axenic culture for molecular analysis. DNA was isolated and a PCR assay was performed for amplification of the Diagnostic fragment 3 (DF3) (~280 bp) region of the 18S rRNA gene from axenic culture of six Acanthamoeba spp. isolates. Rns genotyping was performed on the basis of the variation in nucleotide sequences of DF3 region of the 18S rRNA gene. In the phylogenetic analysis, all of the six Acanthamoeba spp. isolates were found to belong to genotype T4. The sequence homology search for these six isolates in the NCBI databank showed homology with the available strains of Acanthamoeba spp. The newly generated sequences are available in the GenBank database under accession numbers KT004416-KT004421. In the present study, genotype T4 was found as the most prevalent and

  11. Coefficients of different macro–microscopic mass formulae from the AME2012 atomic mass evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Royer, G., E-mail: royer@subatech.in2p3.fr; Subercaze, A.

    2013-11-01

    The coefficients of different possible macro–microscopic mass formulae previously proposed have been adjusted on 2264 experimental atomic masses extracted from the AME2012 atomic mass evaluation [1] assuming N,Z⩾8 and the one standard deviation uncertainty on the mass lower than 150 keV. All the formulae include the volume and surface energies, the Coulomb energy, the diffuseness correction to the sharp radius Coulomb energy, the shell and pairing energies and take into account or not the curvature energy, different forms of the Wigner term, a free charge radius, the experimental equivalent rms charge radius or a fixed short central radius. Masses of 976 more exotic nuclei are extrapolated from the most accurate formula.

  12. Enthalpy By Energy Balance for Aerodynamic Heating Facility at NASA Ames Research Center Arc Jet Complex

    Science.gov (United States)

    Hightower, T. Mark; MacDonald, Christine L.; Martinez, Edward R.; Balboni, John A.; Anderson, Karl F.; Arnold, Jim O. (Technical Monitor)

    2002-01-01

    The NASA Ames Research Center (ARC) Arc Jet Facilities' Aerodynamic Heating Facility (AHF) has been instrumented for the Enthalpy By Energy Balance (EB2) method. Diagnostic EB2 data is routinely taken for all AHF runs. This paper provides an overview of the EB2 method implemented in the AHF. The chief advantage of the AHF implementation over earlier versions is the non-intrusiveness of the instruments used. For example, to measure the change in cooling water temperature, thin film 1000 ohm Resistance Temperature Detectors (RTDs) are used with an Anderson Current Loop (ACL) as the signal conditioner. The ACL with 1000 ohm RTDs allows for very sensitive measurement of the increase in temperature (Delta T) of the cooling water to the arc heater, which is a critical element of the EB2 method. Cooling water flow rates are measured with non-intrusive ultrasonic flow meters.

  13. Building intelligent systems: Artificial intelligence research at NASA Ames Research Center

    Science.gov (United States)

    Friedland, P.; Lum, H.

    1987-01-01

    The basic components that make up the goal of building autonomous intelligent systems are discussed, and ongoing work at the NASA Ames Research Center is described. It is noted that a clear progression of systems can be seen through research settings (both within and external to NASA) to Space Station testbeds to systems which actually fly on the Space Station. The starting point for the discussion is a truly autonomous Space Station intelligent system, responsible for a major portion of Space Station control. Attention is given to research in fiscal 1987, including reasoning under uncertainty, machine learning, causal modeling and simulation, knowledge from design through operations, advanced planning work, validation methodologies, and hierarchical control of and distributed cooperation among multiple knowledge-based systems.

  14. Building intelligent systems - Artificial intelligence research at NASA Ames Research Center

    Science.gov (United States)

    Friedland, Peter; Lum, Henry

    1987-01-01

    The basic components that make up the goal of building autonomous intelligent systems are discussed, and ongoing work at the NASA Ames Research Center is described. It is noted that a clear progression of systems can be seen through research settings (both within and external to NASA) to Space Station testbeds to systems which actually fly on the Space Station. The starting point for the discussion is a 'truly' autonomous Space Station intelligent system, responsible for a major portion of Space Station control. Attention is given to research in fiscal 1987, including reasoning under uncertainty, machine learning, causal modeling and simulation, knowledge from design through operations, advanced planning work, validation methodologies, and hierarchical control of and distributed cooperation among multiple knowledge-based systems.

  15. X-ray K-edge analysis of drain lines in Wilhelm Hall, Ames Laboratory

    International Nuclear Information System (INIS)

    Jensen, T.; Whitmore, C.; Iowa State Univ., Ames, IA

    1999-01-01

    From August 12--27, 1998 X-ray K-edge measurements were made on drain lines in seven rooms in Wilhelm Hall, Ames Laboratory. The purpose of these measurements was to determine the extent of thorium (and other heavy metal) contamination inside these pipes. The K-edge method is a noninvasive inspection technique that can provide accurate quantification of heavy metal contamination interior to an object. Of the seven drain lines inspected, one was found to have no significant contamination, three showed significant thorium deposits, two showed mercury contamination, and one line was found to contain mercury, thorium and uranium. The K-edge measurements were found to be consistent with readings from hand-held survey meters, and provided much greater detail on the location and amount of heavy metal contamination

  16. Development of Implicit Methods in CFD NASA Ames Research Center 1970's - 1980's

    Science.gov (United States)

    Pulliam, Thomas H.

    2010-01-01

    The focus here is on the early development (mid 1970's-1980's) at NASA Ames Research Center of implicit methods in Computational Fluid Dynamics (CFD). A class of implicit finite difference schemes of the Beam and Warming approximate factorization type will be addressed. The emphasis will be on the Euler equations. A review of material pertinent to the solution of the Euler equations within the framework of implicit methods will be presented. The eigensystem of the equations will be used extensively in developing a framework for various methods applied to the Euler equations. The development and analysis of various aspects of this class of schemes will be given along with the motivations behind many of the choices. Various acceleration and efficiency modifications such as matrix reduction, diagonalization and flux split schemes will be presented.

  17. New Diagnostic, Launch and Model Control Techniques in the NASA Ames HFFAF Ballistic Range

    Science.gov (United States)

    Bogdanoff, David W.

    2012-01-01

    This report presents new diagnostic, launch and model control techniques used in the NASA Ames HFFAF ballistic range. High speed movies were used to view the sabot separation process and the passage of the model through the model splap paper. Cavities in the rear of the sabot, to catch the muzzle blast of the gun, were used to control sabot finger separation angles and distances. Inserts were installed in the powder chamber to greatly reduce the ullage volume (empty space) in the chamber. This resulted in much more complete and repeatable combustion of the powder and hence, in much more repeatable muzzle velocities. Sheets of paper or cardstock, impacting one half of the model, were used to control the amplitudes of the model pitch oscillations.

  18. Updates on Modeling the Water Cycle with the NASA Ames Mars Global Climate Model

    Science.gov (United States)

    Kahre, M. A.; Haberle, R. M.; Hollingsworth, J. L.; Montmessin, F.; Brecht, A. S.; Urata, R.; Klassen, D. R.; Wolff, M. J.

    2017-01-01

    Global Circulation Models (GCMs) have made steady progress in simulating the current Mars water cycle. It is now widely recognized that clouds are a critical component that can significantly affect the nature of the simulated water cycle. Two processes in particular are key to implementing clouds in a GCM: the microphysical processes of formation and dissipation, and their radiative effects on heating/ cooling rates. Together, these processes alter the thermal structure, change the dynamics, and regulate inter-hemispheric transport. We have made considerable progress representing these processes in the NASA Ames GCM, particularly in the presence of radiatively active water ice clouds. We present the current state of our group's water cycle modeling efforts, show results from selected simulations, highlight some of the issues, and discuss avenues for further investigation.­

  19. The Ames Dwarf Mutation Attenuates Alzheimer’s Disease Phenotype of APP/PS1 mice

    Science.gov (United States)

    Puig, Kendra L.; Kulas, Joshua A.; Franklin, Whitney; Rakoczy, Sharlene G.; Taglialatela, Giulio; Brown-Borg, Holly M.; Combs, Colin K.

    2016-01-01

    APP/PS1 double transgenic mice expressing human mutant amyloid precursor protein (APP) and presenilin-1 (PS-1) demonstrate robust brain Aβ peptide containing plaque deposition, increased markers of oxidative stress, behavioral dysfunction, and proinflammatory gliosis. On the other hand, lack of growth hormone, prolactin, and thyroid-stimulating hormone due to a recessive mutation in the Prop 1 gene (Prop1df) in Ames dwarf mice results in a phenotype characterized by potentiated anti-oxidant mechanisms, improved learning and memory, and significantly increased longevity in homozygous mice. Based upon this, we hypothesized that a similar hormone deficiency might attenuate disease changes in the brains of APP/PS1 mice. To test this idea, APP/PS1 mice were crossed to the Ames dwarf mouse line. APP/PS1, wild type, df/+, df/df, df/+/APP/PS1, and df/df/APP/PS1 mice were compared at 6 months of age through behavioral testing and assessing amyloid burden, reactive gliosis, and brain cytokine levels. df/df mice demonstrated lower brain growth hormone (GH) and insulin-like growth factor 1 (IGF-1) concentrations. This correlated with decreased astrogliosis and microgliosis in the df/df/APP/PS1 mice and, surprisingly, reduced Aβ plaque deposition and Aβ 1-40 and Aβ 1-42 concentrations. The df/df/APP/PS1 mice also demonstrated significantly elevated brain levels of multiple cytokines in spite of the attenuated gliosis. These data indicate that the df/df/APP/PS1 line is a unique resource in which to study aging and resistance to disease and suggest that the affected pituitary hormones may have a role in regulating disease progression. PMID:26973101

  20. The NASA Ames Research Center Institutional Scientific Collection: History, Best Practices and Scientific Opportunities

    Science.gov (United States)

    Rask, Jon C.; Chakravarty, Kaushik; French, Alison; Choi, Sungshin; Stewart, Helen

    2017-01-01

    The NASA Ames Life Sciences Institutional Scientific Collection (ISC), which is composed of the Ames Life Sciences Data Archive (ALSDA) and the Biospecimen Storage Facility (BSF), is managed by the Space Biosciences Division and has been operational since 1993. The ALSDA is responsible for archiving information and animal biospecimens collected from life science spaceflight experiments and matching ground control experiments. Both fixed and frozen spaceflight and ground tissues are stored in the BSF within the ISC. The ALSDA also manages a Biospecimen Sharing Program, performs curation and long-term storage operations, and makes biospecimens available to the scientific community for research purposes via the Life Science Data Archive public website (https:lsda.jsc.nasa.gov). As part of our best practices, a viability testing plan has been developed for the ISC, which will assess the quality of archived samples. We expect that results from the viability testing will catalyze sample use, enable broader science community interest, and improve operational efficiency of the ISC. The current viability test plan focuses on generating disposition recommendations and is based on using ribonucleic acid (RNA) integrity number (RIN) scores as a criteria for measurement of biospecimen viablity for downstream functional analysis. The plan includes (1) sorting and identification of candidate samples, (2) conducting a statiscally-based power analysis to generate representaive cohorts from the population of stored biospecimens, (3) completion of RIN analysis on select samples, and (4) development of disposition recommendations based on the RIN scores. Results of this work will also support NASA open science initiatives and guides development of the NASA Scientific Collections Directive (a policy on best practices for curation of biological collections). Our RIN-based methodology for characterizing the quality of tissues stored in the ISC since the 1980s also creates unique

  1. Uji Mutagenik Ames untuk Melengkapi Data Keamanan Ekstrak Gambir (Uncaria gambir Roxb.

    Directory of Open Access Journals (Sweden)

    Novi Sulistyaningrum

    2015-05-01

    Full Text Available The main compound of Uncaria gambir Roxb. (gambir, catechin and it’s derivates have been believed to be potential as antiviral. Epigallocatechin gallate (EGCG and epicatechin are catechin derivates which are found to be potential as antiviral against Human Immunodeficiency Virus (HIV. However, gambir extract also contains quercetin that has possibility to be mutagenic. Therefore, a preliminary study towards safety of those compounds within gambir extract, mutagenicity assay using Ames Method has been performed.Sample (gambir extract was obtained from West Sumatera, Indonesia. The extract was characterized according to Farmakope Herbal Indonesia and WHO methods. Mutagenicity test by Ames method utilized a colorimetric microplate in 6 various concentration (125 mg/mL; 62.5 mg/mL; 31.25 mg/mL; 15.625 mg/mL; 7.81 mg/mL dan 3.91 mg/mL against mutant bacteria Salmonella typhimurium TA 98, Salmonella typhimurium TA 100 and Escherichia coli WP2 uvrA with and without the addition of S-9 enzyme. Extract of gambir in this study contains 86.60% of catechin, 12.92% moisture content, 22.49% water-soluble extract content, 80.63% ethanol-soluble extract content, 0.81% total ash, 0.32% acid insoluble ash content and 10.38% in dryness level. From the mutagenicity test and calculation, fold increase (over baseline of the sample in 6 various concentration with and without adding S-9 enzyme are lower than 2. Gambir extract from West Sumatra with catechin contains 86.6% hasn’t showed mutagenic effect due to the fold increase (over baseline of mutagenicity test lower than 2.

  2. Alveolar macrophages infected with Ames or Sterne strain of Bacillus anthracis elicit differential molecular expression patterns.

    Directory of Open Access Journals (Sweden)

    Felicia D Langel

    Full Text Available Alveolar macrophages (AMs phagocytose Bacillus anthracis following inhalation and induce the production of pro-inflammatory cytokines and chemokines to mediate the activation of innate immunity. Ames, the virulent strain of B. anthracis, contains two plasmids that encode the antiphagocytic poly-γ-d-glutamic acid capsule and the lethal toxin. The attenuated Sterne strain of B. anthracis, which lacks the plasmid encoding capsule, is widely adapted as a vaccine strain. Although differences in the outcome of infection with the two strains may have originated from the presence or absence of an anti-phagocytic capsule, the disease pathogenesis following infection will be manifested via the host responses, which is not well understood. To gain understanding of the host responses at cellular level, a microarray analysis was performed using primary rhesus macaque AMs infected with either Ames or Sterne spores. Notably, 528 human orthologs were identified to be differentially expressed in AMs infected with either strain of the B. anthracis. Meta-analyses revealed genes differentially expressed in response to B. anthracis infection were also induced upon infections with multiple pathogens such as Francisella Novicida or Staphylococcus aureus. This suggests the existence of a common molecular signature in response to pathogen infections. Importantly, the microarray and protein expression data for certain cytokines, chemokines and host factors provide further insights on how cellular processes such as innate immune sensing pathways, anti-apoptosis versus apoptosis may be differentially modulated in response to the virulent or vaccine strain of B. anthracis. The reported differences may account for the marked difference in pathogenicity between these two strains.

  3. Identification of a polyketide synthase required for alternariol (AOH and alternariol-9-methyl ether (AME formation in Alternaria alternata.

    Directory of Open Access Journals (Sweden)

    Debjani Saha

    Full Text Available Alternaria alternata produces more than 60 secondary metabolites, among which alternariol (AOH and alternariol-9-methyl ether (AME are important mycotoxins. Whereas the toxicology of these two polyketide-based compounds has been studied, nothing is known about the genetics of their biosynthesis. One of the postulated core enzymes in the biosynthesis of AOH and AME is polyketide synthase (PKS. In a draft genome sequence of A. alternata we identified 10 putative PKS-encoding genes. The timing of the expression of two PKS genes, pksJ and pksH, correlated with the production of AOH and AME. The PksJ and PksH proteins are predicted to be 2222 and 2821 amino acids in length, respectively. They are both iterative type I reducing polyketide synthases. PksJ harbors a peroxisomal targeting sequence at the C-terminus, suggesting that the biosynthesis occurs at least partly in these organelles. In the vicinity of pksJ we found a transcriptional regulator, altR, involved in pksJ induction and a putative methyl transferase, possibly responsible for AME formation. Downregulation of pksJ and altR caused a large decrease of alternariol formation, suggesting that PksJ is the polyketide synthase required for the postulated Claisen condensations during the biosynthesis. No other enzymes appeared to be required. PksH downregulation affected pksJ expression and thus caused an indirect effect on AOH production.

  4. Phenotypic Data Collection and Sample Preparation for Genomics of Wood Formation and Cellulosic Biomass Traits in Sunflower: Ames, IA location.

    Energy Technology Data Exchange (ETDEWEB)

    Marek, Laura F.

    2011-06-17

    Three fields were planted in Ames in 2010, two association mapping fields, N3 and A, and a recombinant inbred line field, N13. Phenotype data and images were transferred to UGA to support genetic and genomic analyses of woody biomass-related traits.

  5. Analysis of plant extracts antimutagenicity using the Ames test and the cytogenetic analysis of peripheral blood lymphocytes

    Czech Academy of Sciences Publication Activity Database

    Buňková, R.; Marová, I.; Pokorná, Z.; Lojek, Antonín

    2005-01-01

    Roč. 11, č. 2 (2005), s. 107-112 ISSN 1082-0132 Institutional research plan: CEZ:AV0Z50040507 Keywords : plant extracts * antioxidative activity * Ames test Subject RIV: BO - Biophysics Impact factor: 0.724, year: 2005

  6. Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice.

    Science.gov (United States)

    Rojanathammanee, Lalida; Rakoczy, Sharlene; Brown-Borg, Holly M

    2014-10-01

    Ames dwarf mice are deficient in growth hormone (GH), prolactin, and thyroid-stimulating hormone and live significantly longer than their wild-type (WT) siblings. The lack of GH is associated with stress resistance and increased longevity. However, the mechanism underlying GH's actions on cellular stress defense have yet to be elucidated. In this study, WT or Ames dwarf mice were treated with saline or GH (WT saline, Dwarf saline, and Dwarf GH) two times daily for 7 days. The body and liver weights of Ames dwarf mice were significantly increased after 7 days of GH administration. Mitochondrial protein levels of the glutathione S-transferase (GST) isozymes, K1 and M4 (GSTK1 and GSTM4), were significantly higher in dwarf mice (Dwarf saline) when compared with WT mice (WT saline). GH administration downregulated the expression of GSTK1 proteins in dwarf mice. We further investigated GST activity from liver lysates using different substrates. Substrate-specific GST activity (bromosulfophthalein, dichloronitrobenzene, and 4-hydrox-ynonenal) was significantly reduced in GH-treated dwarf mice. In addition, GH treatment attenuated the activity of thioredoxin and glutaredoxin in liver mitochondria of Ames mice. Importantly, GH treatment suppressed Trx2 and TrxR2 mRNA expression. These data indicate that GH has a role in stress resistance by altering the functional capacity of the GST system through the regulation of specific GST family members in long-living Ames dwarf mice. It also affects the regulation of thioredoxin and glutaredoxin, factors that regulate posttranslational modification of proteins and redox balance, thereby further influencing stress resistance. © The Author 2013. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  7. Transforming BIM to BEM: Generation of Building Geometry for the NASA Ames Sustainability Base BIM

    Energy Technology Data Exchange (ETDEWEB)

    O' Donnell, James T. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Maile, Tobias [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Rose, Cody [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Mrazovic, Natasa [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Morrissey, Elmer [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Regnier, Cynthia [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Parrish, Kristen [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Bazjanac, Vladimir [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2013-01-01

    Typical processes of whole Building Energy simulation Model (BEM) generation are subjective, labor intensive, time intensive and error prone. Essentially, these typical processes reproduce already existing data, i.e. building models already created by the architect. Accordingly, Lawrence Berkeley National Laboratory (LBNL) developed a semi-automated process that enables reproducible conversions of Building Information Model (BIM) representations of building geometry into a format required by building energy modeling (BEM) tools. This is a generic process that may be applied to all building energy modeling tools but to date has only been used for EnergyPlus. This report describes and demonstrates each stage in the semi-automated process for building geometry using the recently constructed NASA Ames Sustainability Base throughout. This example uses ArchiCAD (Graphisoft, 2012) as the originating CAD tool and EnergyPlus as the concluding whole building energy simulation tool. It is important to note that the process is also applicable for professionals that use other CAD tools such as Revit (“Revit Architecture,” 2012) and DProfiler (Beck Technology, 2012) and can be extended to provide geometry definitions for BEM tools other than EnergyPlus. Geometry Simplification Tool (GST) was used during the NASA Ames project and was the enabling software that facilitated semi-automated data transformations. GST has now been superseded by Space Boundary Tool (SBT-1) and will be referred to as SBT-1 throughout this report. The benefits of this semi-automated process are fourfold: 1) reduce the amount of time and cost required to develop a whole building energy simulation model, 2) enable rapid generation of design alternatives, 3) improve the accuracy of BEMs and 4) result in significantly better performing buildings with significantly lower energy consumption than those created using the traditional design process, especially if the simulation model was used as a predictive

  8. Mis teeb taimest ravimtaime? / Renata Sõukand

    Index Scriptorium Estoniae

    Sõukand, Renata, 1974-

    2007-01-01

    Sünteesides Ilmari Mannineni eesti rahvameditsiini kolmikjaotust Peirceѫi märgitüüpide kolmikjaotusega, järeldab autor, et 19. sajandi eesti taimravi toetub pigem taimega seotud kultuurilistele arusaamadele

  9. Barroso teeb komisjonis muudatusi / Ahto Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Ahto, 1970-

    2004-01-01

    Euroopa Komisjoni president Jose Manuel Barroso lükkas komisjoni hääletuse Euroopa Parlamendis edasi. Autori hinnangul on kindel Itaalia volinikukandidaadi Rocco Buttiglione väljajäämine Euroopa Komisjoni uuest koosseisust, ilmselt tuleb veel teisigi muudatusi. Vt. samas lühiintervjuud Siim Kallasega

  10. Tallink-spaa teeb tallinklaseks / Urmas Oja

    Index Scriptorium Estoniae

    Oja, Urmas, 1981-2012

    2007-01-01

    Tallinnas Viru keskuse vastas asuvast Tallink SPA-hotellist, arhitekt Meelis Press. Sadama tänaval avatud uuest SPA-hotellist, arhitektuuribüroo Urban Mark, sisearhitektid Andro Kööp ja Tairo Pärnamets

  11. Jaapanlastele teeb muret stress / Harli Uljas

    Index Scriptorium Estoniae

    Uljas, Harli

    2002-01-01

    Jaapani tervishoiuministeeriumi andmetel oli möödunud aastal 143 karoshi juhtumit - kõrgeim tase alates 1987. aastast, mil probleemi esimest korda teadvustati. Karoshi - äkksurm ületöötamise tõttu

  12. Võlurpoiss Potter teeb ekraanidel imetrikke / Neeme Raud

    Index Scriptorium Estoniae

    Raud, Neeme, 1969-

    2001-01-01

    Joanne Rowling'u lasteraamatu "Harry Potter ja Tarkade kivi" ekraniseering "Harry Potter and the Philosopher's Stone" esimese kolme linastuspäeva kassatulu USAs ja Kanadas purustas kõik rekordid. Ka kassafilmide esikümne nimekiri

  13. Jutta Rabe teeb Estonia hukust uue filmi

    Index Scriptorium Estoniae

    2002-01-01

    Eile alustas Saksa ajakirjanik Jutta Rabe oma filmi "Baltic Storm" võtetega, mis kujutab parvlaev "Estonia" hukku venelaste vandenõu tulemusena. Peale Rabe on stsenaristid veel saksa advokaat Henning Witte ja rootslane Kaj Holmberg

  14. Mereõhk teeb vabaks / Veronika Valk

    Index Scriptorium Estoniae

    Valk, Veronika, 1976-

    2005-01-01

    Tallinna sadamaalale eri arhitektuurivõistlustel pakutud linnaehituslikele ideedele keskenduv näitus "Back to the Sea" Tallinnas Lootsi tänav 13. Autori fantaasia Tallinna rannala tulevikust. Võrdluseks Barcelona, Helsingborg ja Tel Aviv

  15. Tõde teeb meid vabaks / Tunne Kelam

    Index Scriptorium Estoniae

    Kelam, Tunne, 1936-

    2007-01-01

    Ilmunud ka: Harjumaa, 17. aug. 2007, lk. 2; Nädaline, 18. aug. 2007, lk. 11; Sakala, 22. aug. 2007, lk. 2; Sõnumitooja, 22. aug. 2007, lk. 6; Virumaa Teataja, 22. aug. 2007, lk. 11; Lääne Elu, 23. aug. 2007, lk. 2; Valgamaalane, 23. aug. 2007, lk. 2; Oma Saar, 23. aug. 2007, lk. 5; Põhjarannik, 23. aug. 2007, lk. 4; Järva Teataja, 23. aug. 2007, lk. 2; Võrumaa Teataja, 23. aug. 2007, lk. 2; Maaleht, 30. aug. 2007, lk. 7. Autor meenutab Hirvepargi meeleavaldust 23. augustil 1987

  16. BBC teeb Eestist Eurovisiooni-saadet

    Index Scriptorium Estoniae

    2002-01-01

    Maailma tuntuim avalik-õigusliku tele- ja raadiokompanii British Broadcasting Corporation (BBC) ajakirjanikud käisid detsembri keskel Eestis, et teha pärast Eorovisiooni-võitu Eestist dokumentaalsaade

  17. Collective effects in Au(100-800 AMeV) + Au semi-central collisions; Effets collectifs dans les collisions semi-centrales Au(100-800 AMeV) + Au

    Energy Technology Data Exchange (ETDEWEB)

    Crochet, P.

    1996-04-04

    The present work has been carried out in the framework of the experimental program of the FOPI collaboration. It is devoted to a systematic study of the different forms of collective expansion of nuclear matter in semi-central Au+Au collisions at incident energies ranging from 100 AMeV to 800 AMeV. The aim is to investigate the influence of compressional effects, momentum dependence of the nuclear interaction and nucleon-nucleon cross section on the observed phenomena. Important changes in the reaction mechanisms are evidenced, in particular at low incident energies where one observes, on the one hand, a transition from an enhanced in-plane emission to a preferential out-of-plane emission pattern and, on the other hand, a strong reduction of the directed in-plane component. Experimental results are compared to the predictions of the Quantum Molecular Dynamics (QMD) model for different parametrizations of the nuclear interaction. (author).

  18. Flow Quality Measurements in the NASA Ames Upgraded 11-by 11-Foot Transonic Wind Tunnel

    Science.gov (United States)

    Amaya, Max A.; Murthy, Sreedhara V.; George, M. W. (Technical Monitor)

    2000-01-01

    Among the many upgrades designed and implemented in the NASA Ames 11-by 11-Foot Transonic Wind Tunnel over the past few years, several directly affect flow quality in the test section: a turbulence reduction system with a honeycomb and two screens, a flow smoothing system in the back leg diffusers, an improved drive motor control system, and a full replacement set of composite blades for the compressor. Prior to the shut-down of the tunnel for construction activities, an 8-foot span rake populated with flow instrumentation was traversed in the test section to fully document the flow quality and establish a baseline against which the upgrades could be characterized. A similar set of measurements was performed during the recent integrated system test trials, but the scope was somewhat limited in accordance with the primary objective of such tests, namely to return the tunnel to a fully operational status. These measurements clearly revealed substantial improvements in flow angularity and significant reductions in turbulence level for both full-span and semi-span testing configurations, thus making the flow quality of the tunnel one of the best among existing transonic facilities.

  19. Ames expedited site characterization demonstration at the former manufactured gas plant site, Marshalltown, Iowa

    Energy Technology Data Exchange (ETDEWEB)

    Bevolo, A.J.; Kjartanson, B.H.; Wonder, J.D.

    1996-03-01

    The goal of the Ames Expedited Site Characterization (ESC) project is to evaluate and promote both innovative technologies (IT) and state-of-the-practice technologies (SOPT) for site characterization and monitoring. In April and May 1994, the ESC project conducted site characterization, technology comparison, and stakeholder demonstration activities at a former manufactured gas plant (FMGP) owned by Iowa Electric Services (IES) Utilities, Inc., in Marshalltown, Iowa. Three areas of technology were fielded at the Marshalltown FMGP site: geophysical, analytical and data integration. The geophysical technologies are designed to assess the subsurface geological conditions so that the location, fate and transport of the target contaminants may be assessed and forecasted. The analytical technologies/methods are designed to detect and quantify the target contaminants. The data integration technology area consists of hardware and software systems designed to integrate all the site information compiled and collected into a conceptual site model on a daily basis at the site; this conceptual model then becomes the decision-support tool. Simultaneous fielding of different methods within each of the three areas of technology provided data for direct comparison of the technologies fielded, both SOPT and IT. This document reports the results of the site characterization, technology comparison, and ESC demonstration activities associated with the Marshalltown FMGP site. 124 figs., 27 tabs.

  20. Emission Spectroscopy and Radiometric Measurements in the NASA Ames IHF Arc Jet Facility

    Science.gov (United States)

    Winter, Michael W.; Raiche, George A.; Prabhu, Dinesh K.

    2012-01-01

    Plasma diagnostic measurement campaigns in the NASA Ames Interaction Heating Facility (IHF) have been conducted over the last several years with a view towards characterizing the flow in the arc jet facility by providing data necessary for modeling and simulation. Optical emission spectroscopy has been used in the plenum and in the free jet of the nozzle. Radiation incident over a probe surface has also been measured using radiometry. Plenum measurements have shown distinct radial profiles of temperature over a range of operating conditions. For cases where large amounts of cold air are added radially to the main arc-heated stream, the temperature profiles are higher by as much as 1500 K than the profiles assumed in flow simulations. Optical measurements perpendicular to the flow direction in the free jet showed significant contributions to the molecule emission through inverse pre-dissociation, thus allowing determination of atom number densities from molecular emission. This has been preliminarily demonstrated with the N2 1st Positive System. Despite the use of older rate coefficients, the resulting atom densities are reasonable and surprisingly close to flow predictions.

  1. Ovarian transcriptome associated with reproductive senescence in the long-living Ames dwarf mice.

    Science.gov (United States)

    Schneider, Augusto; Matkovich, Scot J; Saccon, Tatiana; Victoria, Berta; Spinel, Lina; Lavasani, Mitra; Bartke, Andrzej; Golusinski, Pawel; Masternak, Michal M

    2017-01-05

    The aim of the current work was to evaluate the ovarian follicle reserve and the ovarian transcriptome in Ames dwarf (df/df) mice. The results suggest a delayed ovarian aging in df/df mice compared to normal (N) mice. Although a high number of genes were differentially expressed during aging of N mice, only a small fraction of these changed with aging in df/df mice. These alterations involved more than 500 categorized biological processes. The majority of these biological processes, including inflammatory/immune responses, were up-regulated with aging in N mice, while old df/df mice were characterized by down-regulation of these same processes in comparison to age matched N mice. However, biological processes related to DNA damage and repairing were commonly down-regulated with aging in both genotypes. In conclusion, delayed ovarian aging in long-living df/df mice was associated with reduced expression of genes related to the inflammatory and immune responses. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  2. Training for life science experiments in space at the NASA Ames Research Center

    Science.gov (United States)

    Rodrigues, Annette T.; Maese, A. Christopher

    1993-01-01

    As this country prepares for exploration to other planets, the need to understand the affects of long duration exposure to microgravity is evident. The National Aeronautics and Space Administration (NASA) Ames Research Center's Space Life Sciences Payloads Office is responsible for a number of non-human life sciences payloads on NASA's Space Shuttle's Spacelab. Included in this responsibility is the training of those individuals who will be conducting the experiments during flight, the astronauts. Preparing a crew to conduct such experiments requires training protocols that build on simple tasks. Once a defined degree of performance proficiency is met for each task, these tasks are combined to increase the complexity of the activities. As tasks are combined into in-flight operations, they are subjected to time constraints and the crew enhances their skills through repetition. The science objectives must be completely understood by the crew and are critical to the overall training program. Completion of the in-flight activities is proof of success. Because the crew is exposed to the background of early research and plans for post-flight analyses, they have a vested interest in the flight activities. The salient features of this training approach is that it allows for flexibility in implementation, consideration of individual differences, and a greater ability to retain experiment information. This training approach offers another effective alternative training tool to existing methodologies.

  3. Mutagenicity of Tween 80-solvated mild gasification products in the Ames salmonella microsomal assay system

    Energy Technology Data Exchange (ETDEWEB)

    1992-01-13

    The results of the Tween 80-solvated Ames testing of six mild gasification samples indicate significant mutagenic activity only in the composite materials (MG-119 and MG-120), previously suspected from the DMSO-solvated assays, which had shown some variable but ultimately insignificant mutagenic responses. The activity of these samples from the Tween 80-solvated assays was quite low when compared to either the positive controls or the SRC-II HD coal-liquefaction reference material. The class of mutagenic activity expressed by these samples solvated in Tween 80 was that of an indirect-acting, frameshift mutagen(s) since significant activity was found only on tester strain TA98 in the presence of the metabolic activation fraction (S9). Because DMSO and other solvents have been shown to affect the mutagenic activity of certain pure chemicals, the possibility of solvent/mutagen interactions in complex mixtures such as coal-derived liquids exists. Thus, the testing of the genotoxic activity of undefined, chemically complex compounds may require the use of at least two solvent systems to reduce the possibility of artifactual findings. 10 refs., 4 tabs.

  4. Educational Projects in Unmanned Aerial Systems at the NASA Ames Research Center

    Science.gov (United States)

    Dahlgren, Robert P.

    2017-01-01

    Unmanned aerial systems (UAS), autonomy and robotics technology have been fertile ground for developing a wide variety of interdisciplinary student learning opportunities. In this talk, several projects will be described that leverage small fixed-wing UAS that have been modified to carry science payloads. These aircraft provide a unique hands-on experience for a wide range of students from college juniors to graduate students pursuing degrees in electrical engineering, aeronautical engineering, mechanical engineering, applied mathematics, physics, structural engineering and other majors. By combining rapid prototyping, design reuse and open-source philosophies, a sustainable educational program has been organized structured as full-time internships during the summer, part-time internships during the school year, short details for military cadets, and paid positions. As part of this program, every summer one or more UAS is developed from concept through design, build and test phases using the tools and facilities at the NASA Ames Research Center, ultimately obtaining statements of airworthiness and flight release from the Agency before test flights are performed. In 2016 and 2017 student projects focused on the theme of 3D printed modular airframes that may be optimized for a given mission and payload. Now in its fifth year this program has served over 35 students, and has provided a rich learning experience as they learn to rapidly develop new aircraft concepts in a highly regulated environment, on systems that will support principal investigators at university, NASA, and other US federal agencies.

  5. Mutagenicity and antimutagenicity of Salacia crassifolia (mart. Ex. Schult. G. Don. evaluated by Ames test

    Directory of Open Access Journals (Sweden)

    C. C. Carneiro

    2017-09-01

    Full Text Available Abstract Salacia crassifolia (Mart. Ex. Schult. G. Don. is a bush which belongs to Celastraceae family and occurs specially in Brazilian Cerrado. Its leaves, stem, seeds and fruits are popularly used for several medicinal purposes, such as antitumoral, antirheumatic, anti-inflammatory and antimicrobial. In this study, the mutagenic and antimutagenic activities of S. crassifolia stem bark fractions (hexane, ethyl acetate and hydroalcoholic were evaluated by the Ames mutagenicity assay in Salmonella typhimurium TA98 and TA100 strains. By the obtained results, all S. crassifolia fractions did not significantly increase the number of prototrophic revertants for histidine (His+ in both S. typhimurium strains tested (p > 0.05, suggesting absence of mutagenicity. Regarding antimutagenicity, the fractions ethyl acetate and hydroalcoholic significantly decreased the number of His+ revertants colonies induced by positive control for strain TA98 (p < 0.05, demonstrating protection against mutagenicity induced by 4-nitroquinolile1-oxide, whereas the hexane fraction did not show antimutagenic effect in this strain. In the TA100 strain, all fractions of S. crassifolia protected DNA against the harmful action of sodium azide, and the hexane fraction exhibited the greatest protection in this work. Thus, it’s possible conclude that the fractions of S. crassifolia tested in this study could be used in chemoprevention.

  6. Atividade Metanogênica Específica (AME) de lodos industriais provenientes do tratamento biológico aeróbio e anaeróbio

    OpenAIRE

    Schneiders,Danieli; Silva,Joel Dias da; Till,Aline; Lapa,Katt Regina; Pinheiro,Adilson

    2013-01-01

    Nesse estudo procederam-se testes de atividade metanogênica específica (AME) para lodo de indústria têxtil e lodo de indústria alimentícia. O lodo têxtil (aeróbio), proveniente de um sistema de lodos ativados, foi coletado na entrada do decantador biológico secundário e o lodo alimentício (anaeróbio) foi coletado em um reator UASB. Uma vez coletados, os lodos foram caracterizados e submetidos a ensaios de AME. Constatou-se que os microrganismos presentes no lodo alimentício apresentaram AME d...

  7. The Typical Different Features of Grammar of the British English (BrE and American English (AmE

    Directory of Open Access Journals (Sweden)

    I Wayan Dirgeyasa

    2016-08-01

    Full Text Available There are a number of varieties of English all over the world such as American, British, Australian, Indian, Singaporean, Philippine English, etc. However, there are only two varieties of English which are most widely and dominantly taught, learned, and used both spoken and printed around the world namely British English (BrE and American English (AmE. In real sense, the two are often confusing for the non-native learners because they have some differences and uniqueness in some aspects such as spelling, pronunciation, vocabulary, and grammar. Therefore, it is really important for students, teachers and speakers as well to be aware of the major differences between the two. This paper is trying to review some striking unique and different features of grammar of British English (BrE and American English (AmE.

  8. Out-of-plane emission of nuclear matter in Au+Au collisions between 100 and 800 AMeV

    International Nuclear Information System (INIS)

    Bastid, N.; Buta, A.; Crochet, P.

    1996-01-01

    We present new experimental results concerning the azimuthal distributions of light and intermediate mass fragments at midrapidity for Au (100 - 800 AMeV) +Au collisions measured with the phase I setup of the FOPI detector at GSI in Darmstadt. The azimuthal distributions are investigated as a function of the collision centrality, the incident energy, the fragment charge and transverse momentum. The maximum of the azimuthal anisotropy is obtained for collisions associated with impact parameters around 7 fm. Intermediate mass fragments present a stronger out-of-plane emission signal that light fragments. We show in particular that the azimuthal anisotropy as a function of the scaled fragment transverse momentum follows an universal curve for incident energies ranging from 250 to 800 AMeV. A signature for a transition from in-plane to out-of-plane emission is evidenced at the lowest beam energies. (author)

  9. A critical review of the life sciences project management at Ames Research Center for the Spacelab Mission development test 3

    Science.gov (United States)

    Helmreich, R. L.; Wilhelm, J. M.; Tanner, T. A.; Sieber, J. E.; Burgenbauch, S. F.

    1979-01-01

    A management study was initiated by ARC (Ames Research Center) to specify Spacelab Mission Development Test 3 activities and problems. This report documents the problems encountered and provides conclusions and recommendations to project management for current and future ARC life sciences projects. An executive summary of the conclusions and recommendations is provided. The report also addresses broader issues relevant to the conduct of future scientific missions under the constraints imposed by the space environment.

  10. Original Research: Metabolic alterations from early life thyroxine replacement therapy in male Ames dwarf mice are transient.

    Science.gov (United States)

    Darcy, Justin; Fang, Yimin; Hill, Cristal M; McFadden, Sam; Sun, Liou Y; Bartke, Andrzej

    2016-10-01

    Ames dwarf mice are exceptionally long-lived due to a Prop1 loss of function mutation resulting in deficiency of growth hormone, thyroid-stimulating hormone and prolactin. Deficiency in thyroid-stimulating hormone and growth hormone leads to greatly reduced levels of circulating thyroid hormones and insulin-like growth factor 1, as well as a reduction in insulin secretion. Early life growth hormone replacement therapy in Ames dwarf mice significantly shortens their longevity, while early life thyroxine (T4) replacement therapy does not. Possible mechanisms by which early life growth hormone replacement therapy shortens longevity include deleterious effects on glucose homeostasis and energy metabolism, which are long lasting. A mechanism explaining why early life T4 replacement therapy does not shorten longevity remains elusive. Here, we look for a possible explanation as to why early life T4 replacement therapy does not impact longevity of Ames dwarf mice. We found that early life T4 replacement therapy increased body weight and advanced the age of sexual maturation. We also find that early life T4 replacement therapy does not impact glucose tolerance or insulin sensitivity, and any deleterious effects on oxygen consumption, respiratory quotient and heat production are transient. Lastly, we find that early life T4 replacement therapy has long-lasting effects on bone mineral density and bone mineral content. We suggest that the transient effects on energy metabolism and lack of effects on glucose homeostasis are the reasons why there is no shortening of longevity after early life T4 replacement therapy in Ames dwarf mice. © 2016 by the Society for Experimental Biology and Medicine.

  11. Assessing the mutagenic activities of smoke from different cigarettes in direct exposure experiments using the modified Ames Salmonella assay.

    Science.gov (United States)

    Ishikawa, Shinkichi; Kanemaru, Yuki; Nara, Hidenori; Erami, Kazuo; Nagata, Yasufumi

    2016-06-01

    The Ames assay is useful for evaluating the mutagenic potentials of chemicals, and it has been used to evaluate the mutagenic potential of cigarette smoke (CS). In vitro direct exposure systems have been developed to mimic CS exposure in the human respiratory tract, and the Ames assay has been used with such systems. Ames tests were performed using the Vitrocell(®) direct exposure system in this study. The mutagenic potentials of whole mainstream CS and gas/vapor phase fractions produced by conventional combustible cigarettes under two smoking regimens were compared. Salmonella Typhimurium TA98 and TA100 were used with and without metabolic activation, and the number of revertants induced by exposure to each CS was determined. The amount of smoke particles to which cells were exposed were also determined, and dose-response curves describing the relationships between exposure to smoke particles and the number of revertants induced were plotted. The slopes of linear regressions of the dose-response curves were determined, and the slope for each CS was used as a mutagenic activity index for that CS. A new heated cigarette was also tested and smoke from the heated cigarette had a lower mutagenic activity in TA98 and TA100 with metabolic activation than did the conventional CS. The results indicate that the direct exposure system and the Ames test can be used to determine the mutagenic potentials of CS produced by different cigarettes under different conditions (i.e., using different Salmonella Typhimurium strains with and without metabolic activation, and using different smoking conditions). Copyright © 2016 Elsevier B.V. All rights reserved.

  12. A review of recent programs and future plans for rotorcraft in-flight simulation at Ames Research Center

    Science.gov (United States)

    Eshow, Michelle M.; Aiken, Edwin W.; Hindson, William S.; Lebacqz, J. V.; Denery, Dallas G.

    1991-01-01

    A new flight research vehicle, the Rotorcraft-Aircrew Systems Concepts Airborne Laboratory (RASCAL), is being developed by the U.S. Army and NASA at Ames Research Center. The requirements for this new facility stem from a perception of rotorcraft system technology requirements for the next decade together with operational experience with the CH-47B research helicopter that was operated as an in-flight simulator at Ames during the past 10 years. Accordingly, both the principal design features of the CH-47B variable-stability system and the flight-control and cockpit-display programs that were conducted using this aircraft at Ames are reviewed. Another U.S. Army helicopter, a UH-60A Black Hawk, has been selected as the baseline vehicle for the RASCAL. The research programs that influence the design of the RASCAL are summarized, and the resultant requirements for the RASCAL research system are described. These research programs include investigations of advanced, integrated control concepts for achieving high levels of agility and maneuverability, and guidance technologies, employing computer/sensor-aiding, designed to assist the pilot during low-altitude flight in conditions of limited visibility. The approach to the development of the new facility is presented and selected plans for the preliminary design of the RASCAL are described.

  13. General overview of the theories used in assessment: AMEE Guide No. 57.

    Science.gov (United States)

    Schuwirth, Lambert W T; van der Vleuten, Cees P M

    2011-01-01

    There are no scientific theories that are uniquely related to assessment in medical education. There are many theories in adjacent fields, however, that can be informative for assessment in medical education, and in the recent decades they have proven their value. In this AMEE Guide we discuss theories on expertise development and psychometric theories, and the relatively young and emerging framework of assessment for learning. Expertise theories highlight the multistage processes involved. The transition from novice to expert is characterised by an increase in the aggregation of concepts from isolated facts, through semantic networks to illness scripts and instance scripts. The latter two stages enable the expert to recognise the problem quickly and form a quick and accurate representation of the problem in his/her working memory. Striking differences between experts and novices is not per se the possession of more explicit knowledge but the superior organisation of knowledge in his/her brain and pairing it with multiple real experiences, enabling not only better problem solving but also more efficient problem solving. Psychometric theories focus on the validity of the assessment - does it measure what it purports to measure and reliability - are the outcomes of the assessment reproducible. Validity is currently seen as building a train of arguments of how best observations of behaviour (answering a multiple-choice question is also a behaviour) can be translated into scores and how these can be used at the end to make inferences about the construct of interest. Reliability theories can be categorised into classical test theory, generalisability theory and item response theory. All three approaches have specific advantages and disadvantages and different areas of application. Finally in the Guide, we discuss the phenomenon of assessment for learning as opposed to assessment of learning and its implications for current and future development and research.

  14. Viking GCMS Data Restoral and Perceiving Temperature on Other Worlds: Astrobiology Projects at NASA Ames

    Science.gov (United States)

    Guzman, Melissa

    2015-01-01

    The primary task for the summer was to procure the GCMS data from the National Space Science Data Coordinated Archive (NSSDCA) and to assess the current state of the data set for possible reanalysis opportunities. After procurement of the Viking GCMS data set and analysis of its current state, the internship focus shifted to preparing a plan for restoral and archiving of the GCMS data set. A proposal was prepared and submitted to NASA Headquarters to restore and make available the 8000 mass chromatographs that are the basic data generated by the Viking GCMS instrument. The relevance of this restoral and the methodology we propose for restoral is presented. The secondary task for the summer is to develop a thermal model for the perceived temperature of a human standing on Mars, Titan, or Europa. Traditionally, an equation called "Fanger's comfort equation" is used to measure the perceived temperature by a human in a given reference environment. However, there are limitations to this model when applied to other planets. Therefore, the approach for this project has been to derive energy balance equations from first principles and then develop a methodology for correlating "comfort" to energy balance. Using the -20 C walk-in freezer in the Space Sciences building at NASA Ames, energy loss of a human subject is measured. Energy loss for a human being on Mars, Titan and Europa are calculated from first principles. These calculations are compared to the freezer measurements, e.g. for 1 minute on Titan, a human loses as much energy as x minutes in a -20 C freezer. This gives a numerical comparison between the environments. These energy calculations are used to consider the physiological comfort of a human based on the calculated energy losses.

  15. Nectar-secreting Floral Stomata in Maxillaria anceps Ames & C. Schweinf. (Orchidaceae)

    Science.gov (United States)

    DAVIES, K. L.; STPICZYŃSKA, M.; GREGG, A.

    2005-01-01

    • Background and Aims Although it was generally assumed that Maxillaria spp. do not produce nectar, in recent years, nectar has been reported for a number of these orchids. Nevertheless, our current understanding of nectary structure and nectar secretion in Maxillaria is based solely on M. coccinea (Jacq.) L.O. Williams ex Hodge, which, since it shows many features characteristic of ornithophilous flowers, is atypical of this largely entomophilous genus. The aim of the present paper is to describe, for the first time, nectar secretion in a presumed entomophilous species of Maxillaria. • Methods The structure of the nectary of M. anceps Ames & C. Schweinf., nectar composition and the process of nectar secretion were investigated using light microscopy, scanning electron microscopy, transmission electron microscopy, histochemistry, refractometry and high performance liquid chromatography. • Key Results and Conclusions Nectar appears as droplets that are exuded by modified stomata borne upon the labellar callus and collects upon the labellum and at the base of the column-foot. Although such stomata are known to occur in a number of angiosperm families, this is the first time for them to be observed in orchids. The callus consists largely of parenchyma with raphides and is supplied by eight to ten collateral bundles. This tissue, together with the single-layered epidermis, seemingly contains terpenoids. During the bud stage, the callus cells contain an organelle complement consistent with secretory cells whereas by day 4 of anthesis, much of the cell is occupied by a vacuole. The nectar is sucrose-dominant but also contains low concentrations of glucose, fructose, free amino acids and possibly terpenoids. The high sugar concentration (approx. 66 %) is consistent with melittophily and may indicate that, like the majority of Maxillaria spp., M. anceps is visited by stingless bees (Meliponini). PMID:15953790

  16. MicroRNA regulation in Ames dwarf mouse liver may contribute to delayed aging.

    Science.gov (United States)

    Bates, David J; Li, Na; Liang, Ruqiang; Sarojini, Harshini; An, Jin; Masternak, Michal M; Bartke, Andrzej; Wang, Eugenia

    2010-02-01

    The Ames dwarf mouse is well known for its remarkable propensity to delay the onset of aging. Although significant advances have been made demonstrating that this aging phenotype results primarily from an endocrine imbalance, the post-transcriptional regulation of gene expression and its impact on longevity remains to be explored. Towards this end, we present the first comprehensive study by microRNA (miRNA) microarray screening to identify dwarf-specific lead miRNAs, and investigate their roles as pivotal molecular regulators directing the long-lived phenotype. Mapping the signature miRNAs to the inversely expressed putative target genes, followed by in situ immunohistochemical staining and in vitro correlation assays, reveals that dwarf mice post-transcriptionally regulate key proteins of intermediate metabolism, most importantly the biosynthetic pathway involving ornithine decarboxylase and spermidine synthase. Functional assays using 3'-untranslated region reporter constructs in co-transfection experiments confirm that miRNA-27a indeed suppresses the expression of both of these proteins, marking them as probable targets of this miRNA in vivo. Moreover, the putative repressed action of this miRNA on ornithine decarboxylase is identified in dwarf mouse liver as early as 2 months of age. Taken together, our results show that among the altered aspects of intermediate metabolism detected in the dwarf mouse liver--glutathione metabolism, the urea cycle and polyamine biosynthesis--miRNA-27a is a key post-transcriptional control. Furthermore, compared to its normal siblings, the dwarf mouse exhibits a head start in regulating these pathways to control their normality, which may ultimately contribute to its extended health-span and longevity.

  17. Demonstration Of Ohe PIAA Coronagraph For Exoplanet Imaging At NASA Ames.

    Science.gov (United States)

    Belikov, Ruslan; Connelley, M. S.; Greene, T. P.; Guyon, O.; Lynch, D. H.; McKelvey, M. E.; Pluzhnik, E.; Witteborn, F. C.

    2009-01-01

    Direct imaging of extrasolar planets, and Earth-like planets in particular, is an exciting but difficult problem requiring a telescope imaging system with 1010 contrast at separations of 100mas and less. Furthermore, the current NASA science budget may only allow for a small 1-2m space telescope for this task, which puts strong demands on the performance of the imaging instrument. Fortunately, an efficient coronagraph called the Phase Induced Amplitude Apodization (PIAA) has been maturing and may enable Earth-like planet imaging for such small telescopes. NASA Ames is embarking on a laboratory effort to develop a flexible laboratory facility to be operated in air, to demonstrate the PIAA coronagraph as well as the necessary wavefront control and other related technologies. For our wavefront control we are focusing on using small Micro-Electro-Mechanical-System deformable mirrors (MEMS DMs), which promises to reduce the size of the beam and overall instrument, a consideration that becomes very important for small telescopes. In this poster, we describe our lab status and the results to date, as well as plans and expectations for the future. In particular, we have been operating a lens-based PIAA system with a MEMS DM in a passive thermal enclosure, and will describe our latest contrast achieved, wavefront control methods, limiting factors, and methods to overcome those limiting factors. The main limiting factor is expected to be thermal instabilities, which cause mechanical flexures and air currents. For a passive enclosure these are expected to limit contrast to about 107, and to combat this, we are upgrading our enclosure to include active temperature control, which is estimated to provide stability down to the level of 109 contrast.

  18. Surface Lander Missions to Mars: Support via Analysis of the NASA Ames Mars General Circulation Model

    Science.gov (United States)

    Murphy, James R.; Bridger, Alison F.C.; Haberle, Robert M.

    1997-01-01

    We have characterized the near-surface martian wind environment as calculated with a set of numerical simulations carried out with the NASA Ames Mars General Circulation Model (Mars GCM). These wind environments are intended to offer future spacecraft missions to the martian surface a data base from which to choose those locations which meet the mission's criteria for minimal near surface winds to enable a successful landing. We also became involved in the development and testing of the wind sensor which is currently onboard the Mars-bound Pathfinder lander. We began this effort with a comparison of Mars GCM produced winds with those measured by the Viking landers during their descent through the martian atmosphere and their surface wind measurements during the 3+ martian year lifetime of the mission. Unexpected technical difficulties in implementing the sophisticated Planetary Boundary Layer (PBL) scheme of Haberle et al. (1993) within the Mars GCM precluded our carrying out this investigation with the desired improvement to the model's treatment of the PBL. Thus, our results from this effort are not as conclusive as we had anticipated. As it turns out, similar difficulties have been experienced by other Mars modelling groups in attempting to implement very similar PBL routines into their GCMs (Mars General Circulation Model Intercomparison Workshop, held at Oxford University, United Kingdom, July 22-24, 1996; organized by J. Murphy, J. Hollingsworth, M. Joshi). These problems, which arise due to the nature of the time stepping in each of the models, are near to being resolved at the present. The model discussions which follow herein are based upon results using the existing, less sophisticated PBL routine. We fully anticipate implementing the tools we have developed in the present effort to investigate GCM results with the new PBL scheme implemented, and thereafter producing the technical document detailing results from the analysis tools developed during this

  19. Multiyear Simulations of the Martian Water Cycle with the Ames General Circulation Model

    Science.gov (United States)

    Haberle, R. M.; Schaeffer, J. R.; Nelli, S. M.; Murphy, J. R.

    2003-01-01

    Mars atmosphere is carbon dioxide dominated with non-negligible amounts of water vapor and suspended dust particles. The atmospheric dust plays an important role in the heating and cooling of the planet through absorption and emission of radiation. Small dust particles can potentially be carried to great altitudes and affect the temperatures there. Water vapor condensing onto the dust grains can affect the radiative properties of both, as well as their vertical extent. The condensation of water onto a dust grain will change the grain s fall speed and diminish the possibility of dust obtaining high altitudes. In this capacity, water becomes a controlling agent with regard to the vertical distribution of dust. Similarly, the atmosphere s water vapor holding capacity is affected by the amount of dust in the atmosphere. Dust is an excellent green house catalyst; it raises the temperature of the atmosphere, and thus, its water vapor holding capacity. There is, therefore, a potentially significant interplay between the Martian dust and water cycles. Previous research done using global, 3-D computer modeling to better understand the Martian atmosphere treat the dust and the water cycles as two separate and independent processes. The existing Ames numerical model will be employed to simulate the relationship between the Martian dust and water cycles by actually coupling the two cycles. Water will condense onto the dust, allowing the particle's radiative characteristics, fall speeds, and as a result, their vertical distribution to change. Data obtained from the Viking, Mars Pathfinder, and especially the Mars Global Surveyor missions will be used to determine the accuracy of the model results.

  20. IEA Annex XX. Dynamic Inflow effects at fast pitching steps on a wind turbine placed in the NASA-Ames wind tunnel

    Energy Technology Data Exchange (ETDEWEB)

    Schepers, J.G. [ECN Wind Energy, Petten (Netherlands)

    2007-10-15

    The results of a study on dynamic inflow effects are presented and discussed. The study is carried out within the framework of the IEA Annex XX 'Analysis of NASA-Ames wind tunnel measurements'. Use is made of measurements which were taken by NREL (National Renewable Energy Laboratory) on a wind turbine which was placed in the large (24.4 x 36.6m) NASA-Ames wind tunnel.

  1. The microRNA ame-miR-279a regulates sucrose responsiveness of forager honey bees (Apis mellifera).

    Science.gov (United States)

    Liu, Fang; Shi, Tengfei; Yin, Wei; Su, Xin; Qi, Lei; Huang, Zachary Y; Zhang, Shaowu; Yu, Linsheng

    2017-11-01

    Increasing evidence demonstrates that microRNAs (miRNA) play an important role in the regulation of animal behaviours. Honey bees (Apis mellifera) are eusocial insects, with honey bee workers displaying age-dependent behavioural maturation. Many different miRNAs have been implicated in the change of behaviours in honey bees and ame-miR-279a was previously shown to be more highly expressed in nurse bee heads than in those of foragers. However, it was not clear whether this difference in expression was associated with age or task performance. Here we show that ame-miR-279a shows significantly higher expression in the brains of nurse bees relative to forager bees regardless of their ages, and that ame-miR-279a is primarily localized in the Kenyon cells of the mushroom body in both foragers and nurses. Overexpression of ame-miR-279a attenuates the sucrose responsiveness of foragers, while its absence enhances their sucrose responsiveness. Lastly, we determined that ame-miR-279a directly target the mRNA of Mblk-1. These findings suggest that ame-miR-279a plays important roles in regulating honey bee division of labour. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. NMDA and kainate receptor expression, long-term potentiation, and neurogenesis in the hippocampus of long-lived Ames dwarf mice.

    Science.gov (United States)

    Sharma, Sunita; Darland, Diane; Lei, Saobo; Rakoczy, Sharlene; Brown-Borg, Holly M

    2012-06-01

    In the current study, we investigated changes in N-methyl D-aspartate (NMDA) and kainate receptor expression, long-term potentiation (LTP), and neurogenesis in response to neurotoxic stress in long-living Ames dwarf mice. We hypothesized that Ames dwarf mice have enhanced neurogenesis that enables retention of spatial learning and memory with age and promotes neurogenesis in response to injury. Levels of the NMDA receptors (NR)1, NR2A, NR2B, and the kainate receptor (KAR)2 were increased in Ames dwarf mice, relative to wild-type littermates. Quantitative assessment of the excitatory postsynaptic potential in Schaffer collaterals in hippocampal slices from Ames dwarf mice showed an increased response in high-frequency induced LTP over time compared with wild type. Kainic acid (KA) injection was used to promote neurotoxic stress-induced neurogenesis. KA mildly increased the number of doublecortin-positive neurons in wild-type mice, but the response was significantly enhanced in the Ames dwarf mice. Collectively, these data support our hypothesis that the enhanced learning and memory associated with the Ames dwarf mouse may be due to elevated levels of NMDA and KA receptors in hippocampus and their ability to continue producing new neurons in response to neuronal damage.

  3. Long-lived hypopituitary Ames dwarf mice are resistant to the detrimental effects of high-fat diet on metabolic function and energy expenditure.

    Science.gov (United States)

    Hill, Cristal M; Fang, Yimin; Miquet, Johanna G; Sun, Liou Y; Masternak, Michal M; Bartke, Andrzej

    2016-06-01

    Growth hormone (GH) signaling stimulates the production of IGF-1; however, increased GH signaling may induce insulin resistance and can reduce life expectancy in both mice and humans. Interestingly, disruption of GH signaling by reducing plasma GH levels significantly improves health span and extends lifespan in mice, as observed in Ames dwarf mice. In addition, these mice have increased adiposity, yet are more insulin sensitive compared to control mice. Metabolic stressors such as high-fat diet (HFD) promote obesity and may alter longevity through the GH signaling pathway. Therefore, our objective was to investigate the effects of a HFD (metabolic stressor) on genetic mechanisms that regulate metabolism during aging. We show that Ames dwarf mice fed HFD for 12 weeks had an increase in subcutaneous and visceral adiposity as a result of diet-induced obesity, yet are more insulin sensitive and have higher levels of adiponectin compared to control mice fed HFD. Furthermore, energy expenditure was higher in Ames dwarf mice fed HFD than in control mice fed HFD. Additionally, we show that transplant of epididymal white adipose tissue (eWAT) from Ames dwarf mice fed HFD into control mice fed HFD improves their insulin sensitivity. We conclude that Ames dwarf mice are resistant to the detrimental metabolic effects of HFD and that visceral adipose tissue of Ames dwarf mice improves insulin sensitivity in control mice fed HFD. © 2016 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

  4. AMEE Guide 32: e-Learning in medical education Part 1: Learning, teaching and assessment.

    Science.gov (United States)

    Ellaway, Rachel; Masters, Ken

    2008-06-01

    In just a few years, e-learning has become part of the mainstream in medical education. While e-learning means many things to many people, at its heart it is concerned with the educational uses of technology. For the purposes of this guide, we consider the many ways that the information revolution has affected and remediated the practice of healthcare teaching and learning. Deploying new technologies usually introduces tensions, and e-learning is no exception. Some wish to use it merely to perform pre-existing activities more efficiently or faster. Others pursue new ways of thinking and working that the use of such technology affords them. Simultaneously, while education, not technology, is the prime goal (and for healthcare, better patient outcomes), we are also aware that we cannot always predict outcomes. Sometimes, we have to take risks, and 'see what happens.' Serendipity often adds to the excitement of teaching. It certainly adds to the excitement of learning. The use of technology in support of education is not, therefore, a causal or engineered set of practices; rather, it requires creativity and adaptability in response to the specific and changing contexts in which it is used. Medical Education, as with most fields, is grappling with these tensions; the AMEE Guide to e-Learning in Medical Education hopes to help the reader, whether novice or expert, navigate them. This Guide is presented both as an introduction to the novice, and as a resource to more experienced practitioners. It covers a wide range of topics, some in broad outline, and others in more detail. Each section is concluded with a brief 'Take Home Message' which serves as a short summary of the section. The Guide is divided into two parts. The first part introduces the basic concepts of e-learning, e-teaching, and e-assessment, and then focuses on the day-to-day issues of e-learning, looking both at theoretical concepts and practical implementation issues. The second part examines technical

  5. Growth hormone abolishes beneficial effects of calorie restriction in long-lived Ames dwarf mice.

    Science.gov (United States)

    Gesing, Adam; Al-Regaiey, Khalid A; Bartke, Andrzej; Masternak, Michal M

    2014-10-01

    Disruption of the growth hormone (GH) axis promotes longevity and delays aging. In contrast, GH over-expression may lead to accelerated aging and shorter life. Calorie restriction (CR) improves insulin sensitivity and may extend lifespan. Long-lived Ames dwarf (df/df) mice have additional extension of longevity when subjected to 30% CR. The aim of the study was to assess effects of CR or GH replacement therapy separately and as a combined (CR+GH) treatment in GH-deficient df/df and normal mice, on selected metabolic parameters (e.g., insulin, glucose, cholesterol), insulin signaling components (e.g., insulin receptor [IR] β-subunit, phosphorylated form of IR [IR pY1158], protein kinase C ζ/λ [p-PKCζ/λ] and mTOR [p-mTOR]), transcription factor p-CREB, and components of the mitogen-activated protein kinase (MAPK) signaling (p-ERK1/2, p-p38), responsible for cell proliferation, differentiation and survival. CR decreased plasma levels of insulin, glucose, cholesterol and leptin, and increased hepatic IR β-subunit and IR pY1158 levels as well as IR, IRS-1 and GLUT-2 gene expression compared to ad libitum feeding, showing a significant beneficial diet intervention effect. Moreover, hepatic protein levels of p-PKCζ/λ, p-mTOR and p-p38 decreased, and p-CREB increased in CR mice. On the contrary, GH increased levels of glucose, cholesterol and leptin in plasma, and p-mTOR or p-p38 in livers, and decreased plasma adiponectin and hepatic IR β-subunit compared to saline treatment. There were no GH effects on adiponectin in N mice. Moreover, GH replacement therapy did not affect IR, IRS-1 and GLUT-2 gene expression. GH treatment abolishes the beneficial effects of CR; it may suggest an important role of GH-IGF1 axis in mediating the CR action. Suppressed somatotrophic signaling seems to predominate over GH replacement therapy in the context of the examined parameters and signaling pathways. Copyright © 2014 Elsevier Inc. All rights reserved.

  6. Recent Progress in Planetary Laboratory Astrophysics achieved with NASA Ames' COSmIC Facility

    Science.gov (United States)

    Salama, Farid; Sciamma-O'Brien, Ella; Bejaoui, Salma

    2016-10-01

    We describe the characteristics and the capabilities of the laboratory facility, COSmIC, that was developed at NASA Ames to generate, process and analyze interstellar, circumstellar and planetary analogs in the laboratory [1]. COSmIC stands for "Cosmic Simulation Chamber" and is dedicated to the study of neutral and ionized molecules and nanoparticles under the low temperature and high vacuum conditions that are required to simulate various space environments such as planetary atmospheres. COSmIC integrates a variety of state-of-the-art instruments that allow forming, processing and monitoring simulated space conditions for planetary, circumstellar and interstellar materials in the laboratory. The COSmIC experimental setup is composed of a Pulsed Discharge Nozzle (PDN) expansion, that generates a plasma in the stream of a free supersonic jet expansion, coupled to two high-sensitivity, complementary in situ diagnostics: a Cavity Ring Down Spectroscopy (CRDS) and laser induced fluorescence (LIF) systems for photonic detection [2, 3], and a Reflectron Time-Of-Flight Mass Spectrometer (ReTOF-MS) for mass detection [4].Recent results obtained using COSmIC will be highlighted. In particular, the progress that has been achieved in an on-going study investigating the formation and the characterization of laboratory analogs of Titan's aerosols generated from gas-phase molecular precursors [5] will be presented. Plans for future laboratory experiments on planetary molecules and aerosols in the growing field of planetary laboratory astrophysics will also be addressed, as well as the implications of studies underway for astronomical observations.References: [1] Salama F., in Organic Matter in Space, IAU S251, Kwok & Sandford eds, CUP, S251, 4, 357 (2008).[2] Biennier L., Salama, F., Allamandola L., & Scherer J., J. Chem. Phys., 118, 7863 (2003)[3] Tan X, & Salama F., J. Chem. Phys. 122, 84318 (2005)[4] Ricketts C., Contreras C., Walker, R., Salama F., Int. J. Mass Spec, 300

  7. Atmospheric Rotational Effects on Mars Based on the NASA Ames General Circulation Model: Angular Momentum Approach

    Science.gov (United States)

    Sanchez, Braulio V.; Haberle, Robert M.; Schaeffer, James

    2004-01-01

    The objective of the investigation is to determine the motion of the rotational axis of Mars as a result of mass variations in the atmosphere and condensation and sublimation of CO2 ice on the polar caps. A planet experiences this type of motion if it has an atmosphere, which is changing its mass distribution with respect to the solid body of the planet and/or it is asymmetrically changing the amount of ice at the polar caps. The physical principle involved is the conservation of angular momentum, one can get a feeling for it by sitting on a well oiled swivel chair holding a rotating wheel on a horizontal direction and then changing the rotation axis of the wheel to a vertical direction. The person holding the wheel and the chair would begin to rotate in opposite direction to the rotation of the wheel. The motions of Mars atmosphere and the ice caps variations are obtained from a mathematical model developed at the NASA Ames Research Center. The model produces outputs for a time span of one Martian year, which is equivalent to 687 Earth days. The results indicate that Mars axis of rotation moves in a spiral with respect to a reference point on the surface of the planet. It can move as far away as 35.3 cm from the initial location as a result of both mass variations in the atmosphere and asymmetric ice variations at the polar caps. Furthermore the pole performs close to two revolutions around the reference point during a Martian year. This motion is a combination of two motions, one produced by the atmospheric mass variations and another due to the variations in the ice caps. The motion due to the atmospheric variations is a spiral performing about two and a half revolutions around the reference point during which the pole can move as far as 40.9 cm. The motion due to variations in the ice caps is a spiral performing almost three revolutions during which the pole can move as far as 32.8 cm.

  8. An investigation into pharmaceutically relevant mutagenicity data and the influence on Ames predictive potential

    Directory of Open Access Journals (Sweden)

    McCarren Patrick

    2011-11-01

    Full Text Available Abstract Background In drug discovery, a positive Ames test for bacterial mutation presents a significant hurdle to advancing a drug to clinical trials. In a previous paper, we discussed success in predicting the genotoxicity of reagent-sized aryl-amines (ArNH2, a structure frequently found in marketed drugs and in drug discovery, using quantum mechanics calculations of the energy required to generate the DNA-reactive nitrenium intermediate (ArNH:+. In this paper we approach the question of what molecular descriptors could improve these predictions and whether external data sets are appropriate for further training. Results In trying to extend and improve this model beyond this quantum mechanical reaction energy, we faced considerable difficulty, which was surprising considering the long history and success of QSAR model development for this test. Other quantum mechanics descriptors were compared to this reaction energy including AM1 semi-empirical orbital energies, nitrenium formation with alternative leaving groups, nitrenium charge, and aryl-amine anion formation energy. Nitrenium formation energy, regardless of the starting species, was found to be the most useful single descriptor. External sets used in other QSAR investigations did not present the same difficulty using the same methods and descriptors. When considering all substructures rather than just aryl-amines, we also noted a significantly lower performance for the Novartis set. The performance gap between Novartis and external sets persists across different descriptors and learning methods. The profiles of the Novartis and external data are significantly different both in aryl-amines and considering all substructures. The Novartis and external data sets are easily separated in an unsupervised clustering using chemical fingerprints. The chemical differences are discussed and visualized using Kohonen Self-Organizing Maps trained on chemical fingerprints, mutagenic substructure

  9. Mutagenicity of automobile workshop soil leachate and tobacco industry wastewater using the Ames Salmonella fluctuation and the SOS chromotests.

    Science.gov (United States)

    Okunola, Alabi A; Babatunde, Esan E; Chinwe, Duru; Pelumi, Oyedele; Ramatu, Salihu G

    2016-06-01

    Environmental management of industrial solid wastes and wastewater is an important economic and environmental health problem globally. This study evaluated the mutagenic potential of automobile workshop soil-simulated leachate and tobacco wastewater using the SOS chromotest on Escherichia coli PQ37 and the Ames Salmonella fluctuation test on Salmonella typhimurium strains TA98 and TA100 without metabolic activation. Physicochemical parameters of the samples were also analyzed. The result of the Ames test showed mutagenicity of the test samples. However, the TA100 was the more responsive strain for both the simulated leachate and tobacco wastewater in terms of mutagenic index in the absence of metabolic activation. The SOS chromotest results were in agreement with those of the Ames Salmonella fluctuation test. Nevertheless, the E. coli PQ37 system was slightly more sensitive than the Salmonella assay for detecting genotoxins in the tested samples. Iron, cadmium, manganese, copper, nickel, chromium, arsenic, zinc, and lead contents analyzed in the samples were believed to play significant role in the observed mutagenicity in the microbial assays. The results of this study showed that the simulated leachate and tobacco wastewater showed strong indication of a genotoxic risk. Further studies would be required in the analytical field in order to identify and quantify other compounds not analyzed for in this study, some of which could be responsible for the observed genotoxicity. This will be necessary in order to identify the sources of toxicants and thus to take preventive and/or curative measures to limit the toxicity of these types of wastes. © The Author(s) 2014.

  10. M2-F1 mounted in NASA Ames Research Center 40x80 foot wind tunnel

    Science.gov (United States)

    1962-01-01

    After the first attempted ground-tow tests of the M2-F1 in March 1963, the vehicle was taken to the Ames Research Center, Mountain View, CA, for wind-tunnel testing. During these tests, Milt Thompson and others were in the M2-F1 to position the control surfaces for each test. The wingless, lifting body aircraft design was initially conceived as a means of landing an aircraft horizontally after atmospheric reentry. The absence of wings would make the extreme heat of re-entry less damaging to the vehicle. In 1962, Dryden management approved a program to build a lightweight, unpowered lifting body as a prototype to flight test the wingless concept. It would look like a 'flying bathtub,' and was designated the M2-F1, the 'M' referring to 'manned' and 'F' referring to 'flight' version. It featured a plywood shell placed over a tubular steel frame crafted at Dryden. Construction was completed in 1963. The first flight tests of the M2-F1 were over Rogers Dry Lake at the end of a tow rope attached to a hopped-up Pontiac convertible driven at speeds up to about 120 mph. This vehicle needed to be able to tow the M2-F1 on the Rogers Dry Lakebed adjacent to NASA's Flight Research Center (FRC) at a minimum speed of 100 miles per hour. To do that, it had to handle the 400-pound pull of the M2-F1. Walter 'Whitey' Whiteside, who was a retired Air Force maintenance officer working in the FRC's Flight Operations Division, was a dirt-bike rider and hot-rodder. Together with Boyden 'Bud' Bearce in the Procurement and Supply Branch of the FRC, Whitey acquired a Pontiac Catalina convertible with the largest engine available. He took the car to Bill Straup's renowned hot-rod shop near Long Beach for modification. With a special gearbox and racing slicks, the Pontiac could tow the 1,000-pound M2-F1 110 miles per hour in 30 seconds. It proved adequate for the roughly 400 car tows that got the M2-F1 airborne to prove it could fly safely and to train pilots before they were towed behind a C

  11. Model Deformation and Optical Angle of Attack Measurement System in the NASA Ames Unitary Plan Wind Tunnel

    Science.gov (United States)

    Kushner, Laura K.; Drain, Bethany A.; Schairer, Edward T.; Heineck, James T.; Bell, James H.

    2017-01-01

    Both AoA and MDM measurements can be made using an optical system that relies on photogrammetry. Optical measurements are being requested by customers in wind tunnels with increasing frequency due to their non-intrusive nature and recent hardware and software advances that allow measurements to become near real time. The NASA Ames Research Center Unitary Plan Wind Tunnel is currently developing a system based on photogrammetry to measure model deformation and model angle of attack. This paper describes the new system, its development, its use on recent tests and plans to further develop the system.

  12. Critical review of Ames Life Science participation in Spacelab Mission Development Test 3: The SMD 3 management study

    Science.gov (United States)

    Helmreich, R.; Wilhelm, J.; Tanner, T. A.; Sieber, J. E.; Burgenbauch, S.

    1978-01-01

    A management study was conducted to specify activities and problems encountered during the development of procedures for documentation and crew training on experiments, as well as during the design, integration, and delivery of a life sciences experiment payload to Johnson Space Center for a 7 day simulation of a Spacelab mission. Conclusions and recommendations to project management for current and future Ames' life sciences projects are included. Broader issues relevant to the conduct of future scientific missions under the constraints imposed by the environment of space are also addressed.

  13. Office of Health and Environmental Research. Quarterly report, April 1, 1979-June 30, 1979. [Ames Municipal Solid Waste Recovery System

    Energy Technology Data Exchange (ETDEWEB)

    Fassel, V.A.

    1979-10-01

    Progress in the following areas of research reported: characterization of organic pollutants emitted by fossil fuel processing and energy generating plants; environmental effects of using municipal solid wastes as a supplementary fuel; microbiological air quality at the Ames Municipal Solid Waste Recovery System; solid waste to methane environmental study; x-ray and ultraviolet excited optical luminescence (SEOL, UVEOL) of carcinogens - analytical possibilities; laser pumped luminescence (LPL) spectroscopy; and multielement characterization of air particulates. New laser-based methods for the determination of organic pollutants via fluorescence are discussed. (JGB)

  14. In vitro mutagenicity assay (Ames test and phytochemical characterization of seeds oil of Helianthus annuus Linné (sunflower

    Directory of Open Access Journals (Sweden)

    Nelma de Mello Silva Oliveira

    Full Text Available The objective of this research was to investigate the genotoxic potential of the oil of H. annuus L. (sunflower seeds via the Ames test as well as its oxidative properties and lipid composition. The pre-incubation method, system metabolic activation (S9 fraction and five S. typhimurium strains (TA97, TA98, TA100, TA1535 and TA102 were employed for the Ames test. The oxidative stability and fatty acid composition were analyzed by standard methods and gas chromatography. A revertant analysis showed no significant differences between the treatment doses (10–200 μl/plate and the negative controls, regardless of S9+ and S9−, and included all of the S. typhimurium strains. Chromatographic analysis showed high levels of polyunsaturated fatty acids, followed by monounsaturated, saturated and total trans-isomers. Among the polyunsaturated, monounsaturated and saturated fatty acids, linoleic, oleic and palmitic acids predominated. The results suggest that the sunflower oil is not genotoxic as indicated by frameshift mutations and base pair substitutions regardless of the treatment dose, but shows dose-dependent toxicity. The oxidative properties of the sunflower oil were consistent with the requirements of national and international standards. However, its composition could also indicate phytotherapeutic properties. Keywords: Helianthus annuus L., Sunflower oil, Genetic toxicity, Gas chromatography

  15. The micro-Ames test: A direct comparison of the performance and sensitivities of the standard and 24-well plate versions of the bacterial mutation test.

    Science.gov (United States)

    Proudlock, Raymond; Evans, Kristie

    2016-12-01

    "Ames" bacterial mutation tests are widely performed for evaluation and registration of new materials including industrial chemicals, agrochemicals, medical devices, pharmaceuticals, pharmaceutical impurities and other materials. Tests are used to predict their potential long-term adverse health effects (including carcinogenicity). Given their importance, pre-screening 'miniaturized' versions have been developed which allow higher throughput and use less test material, including the widely-employed 24-well micro-AmesAmes) test which uses 20 times less material. However, little quantitative information has been published on the methodology or sensitivity of this system. We describe methods and results used in direct comparisons of the sensitivity of micro and standard systems using the same cultures, formulations, etc. Initial testing utilized the plate incorporation method and, later, the pre-incubation method. In a subsequent phase of testing, a four-way direct comparison was made between the pre-incubation and plate incorporation methods in both systems using some direct-acting mutagens. Tests used only those strain/S9/chemical combinations where a response was expected. Historical control results accumulated during testing are also presented. Spontaneous and induced revertant colony counts for the µAmes system were consistently proportionate and approximately 1/20th those for the standard Ames test. Sensitivities of the two systems were found to be nearly identical in almost all cases for a wide variety of weak and strong inorganic and organic mutagens. Standardized procedures and increased reliability of the estimate of the background revertant frequency in the µAmes system means that the two systems give equivalent results and are expected to be highly predictive of one another. Environ. Mol. Mutagen. 57:687-705, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  16. Proposed Ames M2-F1, M1-L half-cone, and Langley lenticular bodies.

    Science.gov (United States)

    1962-01-01

    acquired a Pontiac Catalina convertible with the largest engine available. He took the car to Bill Straup's renowned hot-rod shop near Long Beach for modification. With a special gearbox and racing slicks, the Pontiac could tow the 1,000-pound M2-F1 110 miles per hour in 30 seconds. It proved adequate for the roughly 400 car tows that got the M2-F1 airborne to prove it could fly safely and to train pilots before they were towed behind a C-47 aircraft and released. These initial car-tow tests produced enough flight data about the M2-F1 to proceed with flights behind the C-47 tow plane at greater altitudes. The C-47 took the craft to an altitude of 12,000 where free flights back to Rogers Dry Lake began. Pilot for the first series of flights of the M2-F1 was NASA research pilot Milt Thompson. Typical glide flights with the M2-F1 lasted about two minutes and reached speeds of 110 to l20 mph. A small solid landing rocket, referred to as the 'instant L/D rocket,' was installed in the rear base of the M2-F1. This rocket, which could be ignited by the pilot, provided about 250 pounds of thrust for about 10 seconds. The rocket could be used to extend the flight time near landing if needed. More than 400 ground tows and 77 aircraft tow flights were carried out with the M2-F1. The success of Dryden's M2-F1 program led to NASA's development and construction of two heavyweight lifting bodies based on studies at NASA's Ames and Langley research centers--the M2-F2 and the HL-10, both built by the Northrop Corporation, and the U.S. Air Force's X-24 program, with an X-24A and -B built by Martin. The Lifting Body program also heavily influenced the Space Shuttle program. The M2-F1 program demonstrated the feasibility of the lifting body concept for horizontal landings of atmospheric entry vehicles. It also demonstrated a procurement and management concept for prototype flight test vehicles that produced rapid results at very low cost (approximately $50,000, excluding salaries of government

  17. Performance of the OVERFLOW-MLP and LAURA-MLP CFD Codes on the NASA Ames 512 CPU Origin System

    Science.gov (United States)

    Taft, James R.

    2000-01-01

    The shared memory Multi-Level Parallelism (MLP) technique, developed last year at NASA Ames has been very successful in dramatically improving the performance of important NASA CFD codes. This new and very simple parallel programming technique was first inserted into the OVERFLOW production CFD code in FY 1998. The OVERFLOW-MLP code's parallel performance scaled linearly to 256 CPUs on the NASA Ames 256 CPU Origin 2000 system (steger). Overall performance exceeded 20.1 GFLOP/s, or about 4.5x the performance of a dedicated 16 CPU C90 system. All of this was achieved without any major modification to the original vector based code. The OVERFLOW-MLP code is now in production on the inhouse Origin systems as well as being used offsite at commercial aerospace companies. Partially as a result of this work, NASA Ames has purchased a new 512 CPU Origin 2000 system to further test the limits of parallel performance for NASA codes of interest. This paper presents the performance obtained from the latest optimization efforts on this machine for the LAURA-MLP and OVERFLOW-MLP codes. The Langley Aerothermodynamics Upwind Relaxation Algorithm (LAURA) code is a key simulation tool in the development of the next generation shuttle, interplanetary reentry vehicles, and nearly all "X" plane development. This code sustains about 4-5 GFLOP/s on a dedicated 16 CPU C90. At this rate, expected workloads would require over 100 C90 CPU years of computing over the next few calendar years. It is not feasible to expect that this would be affordable or available to the user community. Dramatic performance gains on cheaper systems are needed. This code is expected to be perhaps the largest consumer of NASA Ames compute cycles per run in the coming year.The OVERFLOW CFD code is extensively used in the government and commercial aerospace communities to evaluate new aircraft designs. It is one of the largest consumers of NASA supercomputing cycles and large simulations of highly resolved full

  18. Genotoxic, Cytotoxic, Antigenotoxic, and Anticytotoxic Effects of Sulfonamide Chalcone Using the Ames Test and the Mouse Bone Marrow Micronucleus Test.

    Directory of Open Access Journals (Sweden)

    Carolina Ribeiro E Silva

    Full Text Available Chalcones present several biological activities and sulfonamide chalcone derivatives have shown important biological applications, including antitumor activity. In this study, genotoxic, cytotoxic, antigenotoxic, and anticytotoxic activities of the sulfonamide chalcone N-{4-[3-(4-nitrophenylprop-2-enoyl]phenyl} benzenesulfonamide (CPN were assessed using the Salmonella typhimurium reverse mutation test (Ames test and the mouse bone marrow micronucleus test. The results showed that CPN caused a small increase in the number of histidine revertant colonies in S. typhimurium strains TA98 and TA100, but not statistically significant (p > 0.05. The antimutagenicity test showed that CPN significantly decreased the number of His+ revertants in strain TA98 at all doses tested (p 0.05. Additionally, CPN co-administered with MMC significantly increased PCE/NCE ratio at all doses tested, demonstrating its anticytotoxic effect. In summary, CPN presented genotoxic, cytotoxic, antigenotoxic, and anticytotoxic properties.

  19. Preliminary Computational Study for Future Tests in the NASA Ames 9 foot' x 7 foot Wind Tunnel

    Science.gov (United States)

    Pearl, Jason M.; Carter, Melissa B.; Elmiligui, Alaa A.; WInski, Courtney S.; Nayani, Sudheer N.

    2016-01-01

    The NASA Advanced Air Vehicles Program, Commercial Supersonics Technology Project seeks to advance tools and techniques to make over-land supersonic flight feasible. In this study, preliminary computational results are presented for future tests in the NASA Ames 9 foot x 7 foot supersonic wind tunnel to be conducted in early 2016. Shock-plume interactions and their effect on pressure signature are examined for six model geometries. Near- field pressure signatures are assessed using the CFD code USM3D to model the proposed test geometries in free-air. Additionally, results obtained using the commercial grid generation software Pointwise Reigistered Trademark are compared to results using VGRID, the NASA Langley Research Center in-house mesh generation program.

  20. Huellas de las religiones tradicionales del África subsahariana en América Latina y el Caribe

    Directory of Open Access Journals (Sweden)

    Lazaro Cabrera Thompson

    2008-01-01

    Full Text Available El artículo explora las religiones tradicionales practicadas por los pueblos ewe-mina, ewe-fon, bantú y yoruba del África subsahariana, antes de abordar las formas como estas prácticas religiosas persisten en el “Nuevo Mundo” tras la llegada forzosa de aquellos esclavizados africanos. Con base en la presencia de estas religiones tradicionales africanas en distintos países latinoamericanos y caribeño, se evidencia un conjunto religioso fusionado por historias, mitos, leyendas, danza, música, etc. de ascendencia africana y se hace un llamado a los/ as investigadores/as, que desde América Latina y el Caribe, indagan sobre las religiones tradicionales yoruba, para que franqueen los límites de Nigeria con el fin de abarcar a toda la diáspora yoruba.

  1. Acquisition and Analysis of NASA Ames Sunphotometer Measurements during SAGE III Validation Campaigns and other Tropospheric and Stratospheric Research Missions

    Science.gov (United States)

    Livingston, John M.

    2004-01-01

    NASA Cooperative Agreement NCC2-1251 provided funding from April 2001 through December 2003 for Mr. John Livingston of SRI International to collaborate with NASA Ames Research Center scientists and engineers in the acquisition and analysis of airborne sunphotometer measurements during various atmospheric field studies. Mr. Livingston participated in instrument calibrations at Mauna Loa Observatory, pre-mission hardware and software preparations, acquisition and analysis of sunphotometer measurements during the missions, and post-mission analysis of data and reporting of scientific findings. The atmospheric field missions included the spring 2001 Intensive of the Asian Pacific Regional Aerosol Characterization Experiment (ACE-Asia), the Asian Dust Above Monterey-2003 (ADAM-2003) experiment, and the winter 2003 Second SAGE III Ozone Loss and Validation Experiment (SOLVE II).

  2. Adjoint Method and Predictive Control for 1-D Flow in NASA Ames 11-Foot Transonic Wind Tunnel

    Science.gov (United States)

    Nguyen, Nhan; Ardema, Mark

    2006-01-01

    This paper describes a modeling method and a new optimal control approach to investigate a Mach number control problem for the NASA Ames 11-Foot Transonic Wind Tunnel. The flow in the wind tunnel is modeled by the 1-D unsteady Euler equations whose boundary conditions prescribe a controlling action by a compressor. The boundary control inputs to the compressor are in turn controlled by a drive motor system and an inlet guide vane system whose dynamics are modeled by ordinary differential equations. The resulting Euler equations are thus coupled to the ordinary differential equations via the boundary conditions. Optimality conditions are established by an adjoint method and are used to develop a model predictive linear-quadratic optimal control for regulating the Mach number due to a test model disturbance during a continuous pitch

  3. Thermodynamical properties and deexcitation of sources involved in collisions between light nuclei around 100 AMeV incident energy

    International Nuclear Information System (INIS)

    Borderie, B.; Gulminelli, F.; Rivet, M.F.; Dore, D.; Tassan-Got, L.; Bacri, Ch.O.; Ouatizerga, A.; Plagnol, E.; Squalli, M.; Chbihi, A.; Auger, G.; Benlliure, J.; Ecomard, P.; Le Fevre, A.; Marie, N.; Rosato, E.; Saint-Laurent, F.; Wieleczko, J.P.; Durand, D.; Bougault, R.; Brou, R.; Colin, J.; Cussol, D.; Laforest, R.; Lecolley, J.F.; Lefort, T.; Lopez, O.; Louvel, M.; Metivier, V.; Peter, J.; Steckmeyer, J.C.; Tamain, B.; Vient, E.; Parlog, M.; Bisquer, E.; Demeyer, A.; Guinet, D.; Lautesse, P.; Lebreton, L.; Charvet, J.L.; Dayras, R.; De Filippo, E.; Legrain, R.; Nalpas, L.; Volant, C.; Eudes, Ph.; Gourio, D.; Laville, J.L.; Rahmani, A.; Reposeur, T.

    1997-01-01

    Vaporization events, where all species have atomic numbers lower than 3, and deexcitation properties of quasi-projectiles involved in binary dissipative collisions between 36 Ar and 58 Ni are studied with the multidetector INDRA. Kinematical properties and chemical composition (mean values and variances) of vaporizing sources are derived over the excitation energy per nucleon range 8-28 MeV. These data are found in good agreement with the results of a model describing a gas of fermions and bosons in thermal and chemical equilibrium, which strongly suggests that thermodynamical equilibrium has been reached even for such sources produced in very extreme conditions of collisions. Finally, removing the constraint on atomic numbers lower than 3, the evolution of the chemical composition of quasi-projectiles is presented over the excitation energy range 0-25 AMeV. (authors)

  4. Comparative mutability of the Ames tester strains of Salmonella typhimurium by ultraviolet radiation and by 4-nitroquinoline I-oxide

    International Nuclear Information System (INIS)

    Nakano, E.; Ichikawa-Ryo, H.; Kondo, S.

    1982-01-01

    A standard method for determining mutant frequencies per survivor was used to study the detailed kinetics of reverse mutations of Ames tester strains of Salmonella typhimurium induced by UV and by 4NQO. After UV irradiation, strain TA1538 was non-mutable, but its plasmid-containing derivative TA98 was mutable, whereas TA1535 was mutable and its plasmid-bearing derivative TA100 was about 10-fold more mutable. After treatment with 4NQO, TA98 was less mutable than TA1538, whereas TA100 was more mutable than TA1535 by a factor of 10-50. TA1537 was slightly less mutable than TA1535 by either UV or 4NQO. The differential mutabilities of these strains are briefly discussed in relation to the 'hot spot' base sequences for reversion and the nature of DNA damage caused by UV and 4NQO. (orig.)

  5. Genotoxic, Cytotoxic, Antigenotoxic, and Anticytotoxic Effects of Sulfonamide Chalcone Using the Ames Test and the Mouse Bone Marrow Micronucleus Test

    Science.gov (United States)

    Borges, Flávio Fernandes Veloso; Bernardes, Aline; Perez, Caridad Noda; Silva, Daniela de Melo e

    2015-01-01

    Chalcones present several biological activities and sulfonamide chalcone derivatives have shown important biological applications, including antitumor activity. In this study, genotoxic, cytotoxic, antigenotoxic, and anticytotoxic activities of the sulfonamide chalcone N-{4-[3-(4-nitrophenyl)prop-2-enoyl]phenyl} benzenesulfonamide (CPN) were assessed using the Salmonella typhimurium reverse mutation test (Ames test) and the mouse bone marrow micronucleus test. The results showed that CPN caused a small increase in the number of histidine revertant colonies in S. typhimurium strains TA98 and TA100, but not statistically significant (p > 0.05). The antimutagenicity test showed that CPN significantly decreased the number of His+ revertants in strain TA98 at all doses tested (p 0.05). Additionally, CPN co-administered with MMC significantly increased PCE/NCE ratio at all doses tested, demonstrating its anticytotoxic effect. In summary, CPN presented genotoxic, cytotoxic, antigenotoxic, and anticytotoxic properties. PMID:26335560

  6. AMES, NESC and ENIQ: European networks in the field of structural integrity involving NDE and inspection effectiveness assessment

    International Nuclear Information System (INIS)

    Crutzen, S.; Hurst, R.; Debarberis, L.; Lemaitre, P.; Eriksen, B.

    1999-01-01

    Three European networks on structural integrity aspects of ageing nuclear components are presently managed by the Institute for Advanced Materials of the Joint Research Centre of the European Commission: AMES (Ageing Materials Evaluation and Studies), ENIQ (European Network for Inspection Qualification) and NESC (Network for Evaluating Steel Components). All three networks involve actions, which aim at the effectiveness and reliability assessment of NDE techniques and of inspection procedures: Either for materials damage detection and characterisation or for defect detection and evaluation. This paper is describing very generally the objectives of the three networks and is then concentrating on the results obtained in ENIQ, which are relevant with ISI and regulatory issues. (orig./DGE)

  7. Floods of June 17, 1990, and July 9, 1993, along Squaw Creek and the South Skunk River in Ames, Iowa, and vicinity

    Science.gov (United States)

    Einhellig, R.F.; Eash, D.A.

    1996-01-01

    Water-surface-elevation profiles and peak discharges for the floods of June 17, 1990, and July 9, 1993, along Squaw Creek and the South Skunk River, in Ames, Iowa, are presented in this report. The maximum flood-peak discharge of 24,300 cubic feet per second for the streamflow-gaging station on Squaw Creek at Ames, Iowa (station number 05470500) occurred on July 9, 1993. This discharge was 80 percent larger than the 100-year recurrence-interval discharge and exceeded the previous record flood-peak discharge of June 17, 1990, by 94 percent. The July 9, 1993, flood-peak discharge of 26,500 cubic feet per second on the South Skunk River below Squaw Creek (station number 05471000) was also a peak of record, exceeding the previous record flood-peak discharge of June 27, 1975, by 80 percent, and the 100-year recurrence-interval discharge by 60 percent. A flood history describes rainfall conditions for floods that occurred during 1990 and 1993. The report also includes information on flood stages and discharges and floodflow frequencies for the active gaging stations in the vicinity of Ames, Iowa, and on temporary bench marks and reference points in the Squaw Creek and South Skunk River Basins near Ames, Iowa.

  8. Desarrollo y productividad de ñame (Dioscorea trifida y Dioscorea esculenta en diferentes condiciones hídricas

    Directory of Open Access Journals (Sweden)

    Alba Nelly Acevedo Mercado

    2015-01-01

    Full Text Available En la región Montes de María (9° 24' 56,33" N y 75° 23' 04,19" O, departamento de Sucre, Colombia, en zonas de clima cálido (26 °C y 30 °C y de clima medio (20 °C y 24 °C, humedad relativa entre 75 y 85% y precipitación de 750 mm durante el ensayo se estudió el efecto del riego en el desarrollo y productividad de dos especies de ñame en peligro de extinción (Dioscorea trifida y Dioscorea esculenta en un diseño experimental de parcelas subdivididas, donde las variables fueron tres condiciones hídricas: riego de 888 mm durante la etapa crítica del cultivo, riego de 944 mm durante todo el ciclo del cultivo, y ausencia de riego con una oferta de agua de 750 mm provenientes de precipitación. La densidad de siembra fue de 10,000 plantas/ha, labranza tradicional con arado de discos y cosecha 8 meses después de la siembra. Como variables se midieron rendimiento de ñame, contenido de almidón, longitud y diámetro de tubérculos y biomasa aérea. Dioscorea trifida presentó un rendimiento promedio de 30.6 t/ha y D. esculenta de 27 t/ha, con contenidos de almidón de 21.3 y 21.6% en base húmeda, respectivamente; la longitud promedio de tubérculos para D. trifida fue de 17.4 cm y para D. esculenta de 11.4 cm; los diámetros promedio fueron 14.4 cm y 10.5 cm y la biomasa aérea 1.1 kg/planta y 0.67 kg/planta, respectivamente. La aplicación de riego al cultivo produjo un incremento en la producción con respecto al cultivo sin riego, para Dioscorea trifida este incremento fue de 78.9% y para Dioscorea esculenta de 92.9%.

  9. Forgotten marginalia and the French and Latin manuscript tradition in Le Mirouer des simples ames by Marguerite Porete

    Directory of Open Access Journals (Sweden)

    García Acosta, Pablo

    2014-06-01

    Full Text Available This article advocates a fresh critical study of the manuscripts of the “heretical” book, Le Mirouer des simples ames by Marguerite dicta Porete, and an examination of codicological evidence which neither the standard editions nor the modern translations take into account. It argues for analysis of the codex traditionally known as the Chantilly manuscript (Musée Condé, ms. F xiv 26, cat. 157 and of the manuscripts of the Latin branch preserved in the Vatican Library (Biblioteca Apostolica Vaticana, Vat. Lat. 4355; Cod. Rossianus 4; Cod. Chigianus B IV 41; Cod. Chigianus C IV 85 and Vat. Lat. 4953. The analysis focuses on the marginal marks (maniculae, nota bene and iconography which demonstrate that those books were used by active readers. The article also highlights the way in which the marginal marks provide us with information about the transmission and reception of the Mirror, and classifi es them according to function, depending on whether they facilitate access to, evaluate or even contribute to the meaning of the text of the Mirror itself.En las páginas siguientes reivindicamos un retorno crítico al estudio de los manuscritos del libro “herético” escrito por Marguerite dicta Porete (Le Mirouer des simples ames para estudiar aspectos codicológicos que ni las ediciones estándar ni las traducciones modernas han tenido en cuenta. Para ello, proponemos una serie de análisis del llamado “manuscrito de Chantilly” (Musée Condé, ms. F xiv 26, cat. 157 y de los manuscritos de la tradición latina de la Biblioteca Vaticana (Biblioteca Apostolica Vaticana, Vat. Lat. 4355; Cod. Rossianus 4; Cod. Chigianus B IV 41; Cod. Chigianus C IV 85 y Vat. Lat. 4953 basados en las anotaciones marginales (manículas, nota bene e iconografía que identifican estos libros más como dispositivos de lectura que como meros soportes materiales de un texto. Mostraremos cómo tales elementos nos dotan de información sobre la transmisión del texto y

  10. A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins.

    Science.gov (United States)

    Kirkland, David; Reeve, Lesley; Gatehouse, David; Vanparys, Philippe

    2011-03-18

    In vitro genotoxicity testing needs to include tests in both bacterial and mammalian cells, and be able to detect gene mutations, chromosomal damage and aneuploidy. This may be achieved by a combination of the Ames test (detects gene mutations) and the in vitro micronucleus test (MNvit), since the latter detects both chromosomal aberrations and aneuploidy. In this paper we therefore present an analysis of an existing database of rodent carcinogens and a new database of in vivo genotoxins in terms of the in vitro genotoxicity tests needed to detect their in vivo activity. Published in vitro data from at least one test system (most were from the Ames test) were available for 557 carcinogens and 405 in vivo genotoxins. Because there are fewer publications on the MNvit than for other mammalian cell tests, and because the concordance between the MNvit and the in vitro chromosomal aberration (CAvit) test is so high for clastogenic activity, positive results in the CAvit test were taken as indicative of a positive result in the MNvit where there were no, or only inadequate data for the latter. Also, because Hprt and Tk loci both detect gene-mutation activity, a positive Hprt test was taken as indicative of a mouse-lymphoma Tk assay (MLA)-positive, where there were no data for the latter. Almost all of the 962 rodent carcinogens and in vivo genotoxins were detected by an in vitro battery comprising Ames+MNvit. An additional 11 carcinogens and six in vivo genotoxins would apparently be detected by the MLA, but many of these had not been tested in the MNvit or CAvit tests. Only four chemicals emerge as potentially being more readily detected in MLA than in Ames+MNvit--benzyl acetate, toluene, morphine and thiabendazole--and none of these are convincing cases to argue for the inclusion of the MLA in addition to Ames+MNvit. Thus, there is no convincing evidence that any genotoxic rodent carcinogens or in vivo genotoxins would remain undetected in an in vitro test battery

  11. Genotoxicity assessment of biphasic calcium phosphate of modified porosity on human dental pulp cells using Ames and Comet assays.

    Science.gov (United States)

    Wahab, Nur Fathin Alia Che; Kannan, Thirumulu Ponnuraj; Mahmood, Zuliani; Rahman, Ismail Ab; Ismail, Hanafi

    2018-03-01

    Biphasic Calcium Phosphate (BCP) with a ratio of 20/80 Hydroxyapatite (HA)/Beta-tricalcium phosphate (β-TCP) promotes the differentiation of human dental pulp cells (HDPCs). In the current study, the genotoxicity of locally produced BCP of modified porosity (65%) with a mean pore size of 300micrometer (μm) was assessed using Comet and Ames assays. HDPCs were treated with BCP extract at three different inhibitory concentrations which were obtained based on cytotoxicity test conducted with concurrent negative and positive controls. The tail moment of HDPCs treated with BCP extract at all three concentrations showed no significant difference compared to negative control (p>0.05), indicating that BCP did not induce DNA damage to HDPCs. The BCP was evaluated using five tester strains of Salmonella typhimurium TA98, TA100, TA102, TA1537 and TA1538. Each strain was incubated with BCP extract with five different concentrations in the presence and absence of metabolic activation system (S9) mix. Concurrently, negative and positive controls were included. The average number of revertant colonies per plate treated with the BCP extract was less than double as compared to the number of revertant colonies in negative control plate and no dose-related increase was observed. Results from both assays suggested that the BCP of modified porosity did not exhibit any genotoxic effect under the present test conditions. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Building bridges between theory and practice in medical education using a design-based research approach: AMEE Guide No. 60.

    Science.gov (United States)

    Dolmans, Diana H J M; Tigelaar, D

    2012-01-01

    Medical education research has grown enormously over the past 20 years, but it does not sufficiently make use of theories, according to influential leaders and researchers in this field. In this AMEE Guide, it is argued that design-based research (DBR) studies should be conducted much more in medical education design research because these studies both advance the testing and refinement of theories and advance educational practice. In this Guide, the essential characteristics of DBR as well as how DBR differs from other approach such as formative evaluation are explained. It is also explained what the pitfalls and challenges of DBR are. The main challenges deal with how to insure that DBR studies reveal findings that are of a broader relevance than the local situation and how to insure that DBR contributes toward theory testing and refinement. An example of a series of DBR studies on the design of a teaching portfolio in higher education that is aimed at stimulating a teacher's professional development is described, to illustrate how DBR studies actually work in practice. Finally, it is argued that DBR-studies could play an important role in the advancement of theory and practice in the two broad domains of designing or redesigning work-based learning environments and assessment programs.

  13. Prevalência de práticas educativas acerca do aleitamento materno exclusivo (AME em Cuiabá - MT

    Directory of Open Access Journals (Sweden)

    Luma Natalia Barbosa

    2015-03-01

    Full Text Available Objetivo: Descrever a prevalência das práticas educativas em saúde sobre o aleitamento materno exclusivo (AME no Município de Cuiabá - MT nos meses de julho a dezembro de 2012. Métodos: Trata-se de um estudo descritivo transversal, realizado junto a mulheres internadas em um hospital. A amostra foi composta por 306 mulheres no período pós-parto imediato. Os dados foram coletados por meio de um questionário semiestruturado. Resultados: Ter oito anos ou mais de estudo (RP = 1,77; ter renda até dois salários mínimos (RP = 1,22; ter planejado a gravidez (RP = 1,31; ter iniciado o atendimento no serviço de pré-natal no primeiro trimestre (RP = 1,65 e serem primíparas (RP = 1,21 são características que aparecem associadas com uma maior chance de receber orientações sobre aleitamento materno do que as demais mulheres. Conclusão: Faz-se necessário repensar mudanças dessas práticas, a fim de se realizar ações educativas que busquem efetivar transformações na relação profissional/usuário, visando o acolhimento das gestantes.

  14. Metabolic adaptations to short-term every-other-day feeding in long-living Ames dwarf mice.

    Science.gov (United States)

    Brown-Borg, Holly M; Rakoczy, Sharlene

    2013-09-01

    Restrictive dietary interventions exert significant beneficial physiological effects in terms of aging and age-related disease in many species. Every other day feeding (EOD) has been utilized in aging research and shown to mimic many of the positive outcomes consequent with dietary restriction. This study employed long living Ames dwarf mice subjected to EOD feeding to examine the adaptations of the oxidative phosphorylation and antioxidative defense systems to this feeding regimen. Every other day feeding lowered liver glutathione (GSH) concentrations in dwarf and wild type (WT) mice but altered GSH biosynthesis and degradation in WT mice only. The activities of liver OXPHOS enzymes and corresponding proteins declined in WT mice fed EOD while in dwarf animals, the levels were maintained or increased with this feeding regimen. Antioxidative enzymes were differentially affected depending on the tissue, whether proliferative or post-mitotic. Gene expression of components of liver methionine metabolism remained elevated in dwarf mice when compared to WT mice as previously reported however, enzymes responsible for recycling homocysteine to methionine were elevated in both genotypes in response to EOD feeding. The data suggest that the differences in anabolic hormone levels likely affect the sensitivity of long living and control mice to this dietary regimen, with dwarf mice exhibiting fewer responses in comparison to WT mice. These results provide further evidence that dwarf mice may be better protected against metabolic and environmental perturbations which may in turn, contribute to their extended longevity. © 2013.

  15. Environmental Assessment for US Department of Energy support of an Iowa State University Linear Accelerator Facility at Ames, Iowa

    Energy Technology Data Exchange (ETDEWEB)

    1990-05-01

    The proposed Department of Energy (DOE) action is financial and technical support of construction and initial operation of an agricultural commodity irradiator (principally for meat), employing a dual mode electron beam generator capable of producing x-rays, at the Iowa State University Linear Accelerator located at Ames, Iowa. The planned pilot commercial-scale facility would be used for the following activities: conducting irradiation research on agricultural commodities, principally meats; in the future, after the pilot phase, as schedules permit, possibly conducting research on other, non-edible materials; evaluating effects of irradiation on nutritional and sensory quality of agricultural products; demonstrating the efficiency of the process to control or eliminate pathogens, and/or to prolong the commodities' post-harvest shelf-life via control or elimination of bacteria, fungi, and/or insects; providing information to the public on the benefits, safety and risks of irradiated agricultural commodities; determining consumer acceptability of the irradiated products; providing data for use by regulatory agencies in developing protocols for various treatments of Iowa agricultural commodities; and training operators, maintenance and quality control technicians, scientists, engineers, and staff of regulatory agencies in agricultural commodity irradiation technology. 14 refs., 5 figs.

  16. Sex determination of cattle meat by polymerase chain reaction amplification of the amelogenin (AMELX/AMELY gene

    Directory of Open Access Journals (Sweden)

    P. Gokulakrishnan

    Full Text Available Aim: The objective of this study was to develop a simplified, efficient, and accurate protocol for sexing of cattle meat based on the amelogenin (AMELX/AMELY gene using PCR technique which is superior to earlier work in terms of band patterns. Materials and Methods: Based on the amelogenin gene located on the conservation region of X and Y chromosomes, a pair of primers was designed and the system of PCR was established to amplify a 241-bp fragment from the X chromosome in female cattle, and a 241-bp fragment from X chromosome and 178-bp fragment from the Y chromosome in male cattle, respectively. The accuracy and specificity of the primers was assessed using DNA template extracted from cattle meat samples of known sex. The protocol was subjected to a blind test showed 100% concordance, proving its accuracy and reliability. Results: PCR products of cattle meat samples after electrophoresis showed two bands (241, 178-bp for tissue from male while female tissue resulted in only one (241-bp band. Conclusions: Our findings show that the PCR assay based on the amelogenin gene is reliable for sex determination in cattle meat. [Vet World 2012; 5(9.000: 526-529

  17. Exploring reaction mechanisms and their competition in 58Ni+48Ca collisions at E = 25 AMeV

    Directory of Open Access Journals (Sweden)

    Francalanza L.

    2014-03-01

    Full Text Available Latest results concerning the study of central collisions in 58Ni+48Ca reactions at Elab(Ni=25 AMeV are presented. The experimental data, collected with the CHIMERA 4π device, have been analyzed in order to investigate the competition among different reaction mechanisms for central collisions in the Fermi energy domain. The method adopted to perform the centrality selection refers to the global variable “flow angle”, that is related to the event shape in momentum space, as it is determined by the eigenvectors of the experimental kinetic-energy tensor. The main features of the reaction products were explored by using different constraints on some of the relevant observables, such as mass and velocity distributions and their correlations. Much emphasis was devoted to the competition between fusion-evaporation processes with subsequent identification of a heavy residue and a prompt multifragmentation mechanism. The reaction mechanism was simulated in the framework of transport theories (dynamical stochastic BNV calculations, followed by sequential SIMON code and further comparison with dynamical calculations from transport model (QMD, CoMD are in progress. Moreover, an extension of this study taking into account for the light particles has been envisaged.

  18. Measurement of isotopic cross sections of the fission fragments produced in 500 AMeV 208Pb + p reaction

    International Nuclear Information System (INIS)

    Fernandez-Dominguez, B.

    2003-03-01

    The aim of this work is the study of the fission fragments produced in the spallation reaction 208 Pb + p at 500 AMeV. The fission fragments from Z=23 up to Z=59 have been detected and identified by using the inverse kinematics technique with the high-resolution spectrometer FRS. The production cross sections and the recoil velocities of 430 nuclei have been measured. The measured data have been compared with previous data. The isotopic distributions show a high precision. However, the absolute value of the fission cross section is higher than expected. From the experimental data the characteristics of the average fissioning system have been reconstructed (Z fis , A fis , E* fis ). In addition, the number of post-fission neutrons emitted from the fission fragments, v post , has been determined by using a new method. The experimental data have been compared to the two-steps models describing the spallation reaction. The impact of the model parameters on the observables has been analysed and the reasons Leading to the observed differences between the codes are also presented. This analyse shows a good agreement with the INCL4+ABLA code. (author)

  19. Partitioning of nuclei in central 129Xe + natSn collisions from 25 to 50 AMeV

    International Nuclear Information System (INIS)

    Dayras, R.; Charvet, J.L.; Nalpas, L.; Volant, C.

    2003-01-01

    Charge distributions measured in central 129 Xe + Sn(nat) collisions from 25 to 50 A*MeV bombarding energy are analyzed in the framework of a random break-up model. Many aspects of the data stem from finite size effects. This simple approach based on integer number decomposition gives a remarkable description of the data for bombarding energies equal or greater than 39 A*MeV. One plausible explanation of the evolution observed with bombarding energy is that above 39 AMeV incident energy, the excitation energy of the system is such that all partitions become likely. When the incident energy is lowered the partitions consuming the largest amount of energy become unfavourable. This will happen first for low IMF (intermediate mass fragment) multiplicity events in which a large amount of light fragments and particles are produced, consuming a large amount of the available energy. An alternative interpretation is to assume that above 39 A*MeV bombarding energy the system enters a completely disordered phase. The scaling law observed between the Z b distributions suggests that it may be possible to find a unique distribution permitting a unified description of the data at a given bombarding energy

  20. ACLIMATIZACIÓN DE PLÁNTULAS DE YAMPÍ (Dioscorea trifida Y ÑAME (D. alata PRODUCIDAS in vitro

    Directory of Open Access Journals (Sweden)

    Ana Gabriela Chacón

    2005-01-01

    Full Text Available La siembra de yampí (Dioscorea trifida y ñame (D. alata en Costa Rica se realiza primordialmente con fines de exportación a Europa y Norteamérica. La producción nacional se ve seriamente limitada por la falta de semilla libre de plagas y enfermedades. Aunque la producción in vitro de semilla representa una alternativa, una sobrevivencia baja de las plántulas durante la aclimatización limita la aplicación comercial de esta tecnología. Se evaluó el efecto del paclobutrazol, la edad al trasplante, la humedad durante el período de aclimatización y el uso de un antitranspirante. Se encontró que la edad al trasplante y la regulación de la humedad durante las primeras etapas de la fase de aclimatización son factores importantes en la sobrevivencia de las plántulas de Dioscorea producidas in vitro, y su crecimiento durante las primeras 6 semanas ex vitro.

  1. Optimizing Facility Configurations and Operating Conditions for Improved Performance in the NASA Ames 24 Inch Shock Tube

    Science.gov (United States)

    Bogdanoff, David W.; Cruden, Brett A.

    2016-01-01

    The Ames Electric Arc Shock Tube (EAST) is a shock tube wherein the driver gas can be heated by an electric arc discharge. The electrical energy is stored in a 1.2 MJ capacitor bank. Four inch and 24 inch diameter driven tubes are available. The facility is described and the need for testing in the 24 inch tube to better simulate low density NASA mission profiles is discussed. Three test entries, 53, 53B and 59, are discussed. Tests are done with air or Mars gas (95.7% CO2/2.7% N2/1.6% Ar) at pressures of 0.01 to 0.14 Torr. Velocities spanned 6.3-9.2 km/s, with a nominal center of 7 km/s. Many facility configurations are studied in an effort to improve data quality. Various driver and driven tube configurations and the use of a buffer section between the driver and the driven tube are studied. Diagnostics include test times, time histories of the shock light pulses and tilts of the shock wave off the plane normal to the tube axis. The report will detail the results of the various trials, give the best configuration/operating conditions found to date and provide recommendations for further improvements. Finally, diaphragm performance is discussed.

  2. Communication skills: an essential component of medical curricula. Part I: Assessment of clinical communication: AMEE Guide No. 51.

    Science.gov (United States)

    Laidlaw, Anita; Hart, Jo

    2011-01-01

    This AMEE Guide in Medical Education is Part 1 of a two part Guide covering the issues of Communication. This Guide has been written to provide guidance for those involved in planning the assessment of clinical communication and provides guidance and information relating to the assessment of various aspects of clinical communication; its underlying theory; its practical ability to show that an individual is competent and its relationship to students' daily performance. The advantages and disadvantages of assessing specific aspects of communication are also discussed. The Guide draws attention to the complexity of assessing the ability to communicate with patients and healthcare professionals, with issues of reliability and validity being highlighted for each aspect. Current debates within the area of clinical communication teaching are raised: when should the assessment of clinical communication occur in undergraduate medical education?; should clinical communication assessment be integrated with clinical skills assessment, or should the two be separate?; how important should the assessment of clinical communication be, and the question of possible failure of students if they are judged not competent in communication skills? It is the aim of the authors not only to provide a useful reference for those starting to develop their assessment processes, but also provide an opportunity for review and debate amongst those who already assess clinical communication within their curricula, and a resource for those who have a general interest in medical education who wish to learn more about communication skills assessment.

  3. Report of the Interagency Optical Network Testbeds Workshop 2, NASA Ames Research Center, September 12-14, 2005

    Science.gov (United States)

    2005-01-01

    The Optical Network Testbeds Workshop 2 (ONT2), held on September 12-14, 2005, was cosponsored by the Department of Energy Office of Science (DOE/SC) and the National Aeronautics and Space Administration (NASA), in cooperation with the Joint Engineering Team (JET) of the Federal Networking and Information Technology Research and Development (NITRD) Program's Large Scale Networking (LSN) Coordinating Group. The ONT2 workshop was a follow-on to an August 2004 Workshop on Optical Network Testbeds (ONT1). ONT1 recommended actions by the Federal agencies to assure timely development and implementation of optical networking technologies and infrastructure. Hosted by the NASA Ames Research Center in Mountain View, California, the ONT2 workshop brought together representatives of the U.S. advanced research and education (R&E) networks, regional optical networks (RONs), service providers, international networking organizations, and senior engineering and R&D managers from Federal agencies and national research laboratories. Its purpose was to develop a common vision of the optical network technologies, services, infrastructure, and organizations needed to enable widespread use of optical networks; recommend activities for transitioning the optical networking research community and its current infrastructure to leading-edge optical networks over the next three to five years; and present information enabling commercial network infrastructure providers to plan for and use leading-edge optical network services in that time frame.

  4. IEA Annex XX. Comparison between calculations and measurements on a wind turbine in yaw in the NASA-Ames wind tunnel

    Energy Technology Data Exchange (ETDEWEB)

    Schepers, J.G. [ECN Wind Energy, Petten (Netherlands)

    2007-10-15

    This report describes a study in which calculational results from ECN's aeroelastic code PHATAS and the free wake lifting line code AWSM are compared with measurements which were performed by NREL (National Renewable Energy Laboratory) on a wind turbine, placed in the large NASA-Ames wind tunnel. Measurements have been taken at a large variety of conditions but in this report only data at yawed conditions are considered. An important advantage of the present measurements is formed by the wind tunnel environment, which provides a very constant and homogeneous yaw angle and wind speed. The study was carried out within the framework IEA Annex XX 'Analysis of NASA-Ames wind tunnel measurements'.

  5. Analytical study of the effects of wind tunnel turbulence on turbofan rotor noise. [NASA Ames 40 by 80 foot wind tunnel

    Science.gov (United States)

    Gliebe, P. R.; Kerschen, E. J.

    1979-01-01

    The influence of tunnel turbulence on turbofan rotor noise was carried out to evaluate the effectiveness of the NASA Ames 40 by 80 foot tunnel in simulating flight levels of fan noise. A previously developed theory for predicting rotor/turbulence interaction noise was refined and extended to include first-order effects of inlet turbulence anisotropy. This theory was then verified by carrying out extensive data/theory comparisons. The resulting model computer program was then employed to carry out a parametric study of the effects of fan size, blade number, and operating line on rotor/turbulence noise for outdoor test stand. NASA Ames wind tunnel, and flight inlet turbulence conditions. A major result of this study is that although wind tunnel rotor/turbulence noise levels are not as low as flight levels they are substantially lower than the outdoor test stand levels and do not mask other sources of fan noise.

  6. Axisymmetric & non-axisymmetric exhaust jet induced-effects on a V/STOL vehicle design. Part 1: Data presentation. [conducted in Ames 11-foot transonic tunnel

    Science.gov (United States)

    Schnell, W. C.; Ordonez, G. W.

    1981-01-01

    A 1/8 scale jet-effects model was tested in the NASA Ames 11 ft transonic tunnel at static conditions and over a range of Mach numbers from 0.4 to 1.4. The data presented show that significant differences in aeropropulsion performance can be expected by varying the exhaust nozzle type and its geometric parameters on a V/STOL underwing nacelle installation.

  7. NATO Allied Medical Publication 7.5 Study Draft 3 (AMedP 7.5 SD.3), NATO Planning Guide for the Estimation of CBRN Casualties

    Science.gov (United States)

    2015-12-01

    Cl2), ammonia (NH3), hydrogen cyanide (AC), cyanogen chloride (CK), and hydrogen sulfide (H2S). Table 1-1: Chemical Agent Challenge Types Agent...agent poisoning symptoms in some personnel. 3) Donning IPE or taking shelter in response to a detector alarm. AMedP-7.5 2-3 SD.3 2.1.2...LIST OF ACRONYMS AND ABBREVIATIONS AAP Allied Administration Publication AC Hydrogen cyanide ACH Air changes per hour AJP Allied Joint Publication

  8. THE NASA AMES PAH IR SPECTROSCOPIC DATABASE VERSION 2.00: UPDATED CONTENT, WEB SITE, AND ON(OFF)LINE TOOLS

    Energy Technology Data Exchange (ETDEWEB)

    Boersma, C.; Mattioda, A. L.; Allamandola, L. J. [NASA Ames Research Center, MS 245-6, Moffett Field, CA 94035 (United States); Bauschlicher, C. W. Jr.; Ricca, A. [NASA Ames Research Center, MS 230-3, Moffett Field, CA 94035 (United States); Cami, J.; Peeters, E.; De Armas, F. Sánchez; Saborido, G. Puerta [SETI Institute, 189 Bernardo Avenue 100, Mountain View, CA 94043 (United States); Hudgins, D. M., E-mail: Christiaan.Boersma@nasa.gov [NASA Headquarters, MS 3Y28, 300 E St. SW, Washington, DC 20546 (United States)

    2014-03-01

    A significantly updated version of the NASA Ames PAH IR Spectroscopic Database, the first major revision since its release in 2010, is presented. The current version, version 2.00, contains 700 computational and 75 experimental spectra compared, respectively, with 583 and 60 in the initial release. The spectra span the 2.5-4000 μm (4000-2.5 cm{sup -1}) range. New tools are available on the site that allow one to analyze spectra in the database and compare them with imported astronomical spectra as well as a suite of IDL object classes (a collection of programs utilizing IDL's object-oriented programming capabilities) that permit offline analysis called the AmesPAHdbIDLSuite. Most noteworthy among the additions are the extension of the computational spectroscopic database to include a number of significantly larger polycyclic aromatic hydrocarbons (PAHs), the ability to visualize the molecular atomic motions corresponding to each vibrational mode, and a new tool that allows one to perform a non-negative least-squares fit of an imported astronomical spectrum with PAH spectra in the computational database. Finally, a methodology is described in the Appendix, and implemented using the AmesPAHdbIDLSuite, that allows the user to enforce charge balance during the fitting procedure.

  9. Prevention of neuromusculoskeletal frailty in slow-aging ames dwarf mice: longitudinal investigation of interaction of longevity genes and caloric restriction.

    Directory of Open Access Journals (Sweden)

    Oge Arum

    Full Text Available Ames dwarf (Prop1 (df/df mice are remarkably long-lived and exhibit many characteristics of delayed aging and extended healthspan. Caloric restriction (CR has similar effects on healthspan and lifespan, and causes an extension of longevity in Ames dwarf mice. Our study objective was to determine whether Ames dwarfism or CR influence neuromusculoskeletal function in middle-aged (82 ± 12 weeks old or old (128 ± 14 w.o. mice. At the examined ages, strength was improved by dwarfism, CR, and dwarfism plus CR in male mice; balance/ motor coordination was improved by CR in old animals and in middle-aged females; and agility/ motor coordination was improved by a combination of dwarfism and CR in both genders of middle-aged mice and in old females. Therefore, extension of longevity by congenital hypopituitarism is associated with improved maintenance of the examined measures of strength, agility, and motor coordination, key elements of frailty during human aging, into advanced age. This study serves as a particularly important example of knowledge related to addressing aging-associated diseases and disorders that results from studies in long-lived mammals.

  10. Prevention of neuromusculoskeletal frailty in slow-aging ames dwarf mice: longitudinal investigation of interaction of longevity genes and caloric restriction.

    Science.gov (United States)

    Arum, Oge; Rasche, Zachary Andrew; Rickman, Dustin John; Bartke, Andrzej

    2013-01-01

    Ames dwarf (Prop1 (df/df) ) mice are remarkably long-lived and exhibit many characteristics of delayed aging and extended healthspan. Caloric restriction (CR) has similar effects on healthspan and lifespan, and causes an extension of longevity in Ames dwarf mice. Our study objective was to determine whether Ames dwarfism or CR influence neuromusculoskeletal function in middle-aged (82 ± 12 weeks old) or old (128 ± 14 w.o.) mice. At the examined ages, strength was improved by dwarfism, CR, and dwarfism plus CR in male mice; balance/ motor coordination was improved by CR in old animals and in middle-aged females; and agility/ motor coordination was improved by a combination of dwarfism and CR in both genders of middle-aged mice and in old females. Therefore, extension of longevity by congenital hypopituitarism is associated with improved maintenance of the examined measures of strength, agility, and motor coordination, key elements of frailty during human aging, into advanced age. This study serves as a particularly important example of knowledge related to addressing aging-associated diseases and disorders that results from studies in long-lived mammals.

  11. Prophage induction, mutagenesis, and cell survival of Ames' mutagen tester strains after 8-methoxypsoralen plus ultraviolet light-A

    Energy Technology Data Exchange (ETDEWEB)

    Wheeler, L.A.; DeMeo, M. (California Univ., Los Angeles (USA)); Lowe, N. (Combined UCLA-WADSWORTH Dermatology Program, Los Angeles, CA (USA))

    1983-10-01

    8-methoxypsoralen (8-MOP) is not detected as a mutagen in the standard Ames test either in the presence or absence of S9-mix and/or ultraviolet light-A (320-400 nm). The Ames strains have been shown to harbor bacteriophages that are inducible by carcinogens and mutagens. Psoralen plus UVA (PUVA) was found to be a potent prophage inducing treatment. Induction was observed in TA1535, TA1538, TA98, TA100, TA1978 and TA1975 with 8-MOP and UVA. PUVA is a potent bactericidal treatment at concentrations of 8-MOP above 0.5 ..mu..g/ml and 2.5 kJ/m/sup 2/ in tester strains TA1535, TA1538, TA98 and TA100. PUVA is known to be bactericidal, but the cytotoxicity observed in the present study was unique in that the frameshift tester strains (TA1538 and TA98) were more sensitive to the lethal effects of PUVA than the base pair tester strains (TA1535 and TA100). The differential cytotoxicity in such closely related strains led to the examination of some of the strains from which the Ames strains were derived. It is postulated that TA1535 retains a DNA repair function that is lost by TA1538 during the selection for uvrB deficient strains.

  12. Indexing of randomised controlled trials of physiotherapy interventions: a comparison of AMED, CENTRAL, CINAHL, EMBASE, hooked on evidence, PEDro, PsycINFO and PubMed.

    Science.gov (United States)

    Moseley, Anne M; Sherrington, Catherine; Elkins, Mark R; Herbert, Robert D; Maher, Christopher G

    2009-09-01

    To compare the comprehensiveness of indexing the reports of randomised controlled trials of physiotherapy interventions by eight bibliographic databases (AMED, CENTRAL, CINAHL, EMBASE, Hooked on Evidence, PEDro, PsycINFO and PubMed). Audit of bibliographic databases. Two hundred and eighty-one reports of randomised controlled trials of physiotherapy interventions were identified by screening the reference lists of 30 relevant systematic reviews published in four consecutive issues of the Cochrane Database of Systematic Reviews (Issue 3, 2007 to Issue 2, 2008). AMED, CENTRAL, CINAHL, EMBASE, Hooked on Evidence, PEDro, PsycINFO and PubMed were used to search for the trial reports. The number of trial reports indexed in each database was calculated. PEDro indexed 99% of the trial reports, CENTRAL indexed 98%, PubMed indexed 91%, EMBASE indexed 82%, CINAHL indexed 61%, Hooked on Evidence indexed 40%, AMED indexed 36% and PsycINFO indexed 17%. Most trial reports (92%) were indexed on four or more of the databases. One trial report was indexed on a single database (PEDro). Of the eight bibliographic databases examined, PEDro and CENTRAL provide the most comprehensive indexing of reports of randomised trials of physiotherapy interventions.

  13. Piloted Evaluation of Modernized Limited Authority Control Laws in the NASA-Ames Vertical Motion Simulator (VMS)

    Science.gov (United States)

    Sahasrabudhe, Vineet; Melkers, Edgar; Faynberg, Alexander; Blanken, Chris L.

    2003-01-01

    The UH-60 BLACK HAWK was designed in the 1970s, when the US Army primarily operated during the day in good visual conditions. Subsequently, the introduction of night-vision goggles increased the BLACK HAWK'S mission effectiveness, but the accident rate also increased. The increased accident rate is strongly tied to increased pilot workload as a result of a degradation in visual cues. Over twenty years of research in helicopter flight control and handling qualities has shown that these degraded handling qualities can be recovered by modifying the response type of the helicopter in low speed flight. Sikorsky Aircraft Corporation initiated a project under the National Rotorcraft Technology Center (NRTC) to develop modern flight control laws while utilizing the existing partial authority Stability Augmentation System (SAS) of the BLACK HAWK. This effort resulted in a set of Modernized Control Laws (MCLAWS) that incorporate rate command and attitude command response types. Sikorsky and the US Army Aeroflightdynamics Directorate (AFDD) conducted a piloted simulation on the NASA-Ames Vertical h4otion Simulator, to assess potential handling qualities and to reduce the risk of subsequent implementation and flight test of these modern control laws on AFDD's EH-60L helicopter. The simulation showed that Attitude Command Attitude Hold control laws in pitch and roll improve handling qualities in the low speed flight regime. These improvements are consistent across a range of mission task elements and for both good and degraded visual environments. The MCLAWS perform better than the baseline UH-60A control laws in the presence of wind and turbulence. Finally, while the improved handling qualities in the pitch and roll axis allow the pilot to pay more attention to the vertical axis and hence altitude performance also improves, it is clear from pilot comments and altitude excursions that the addition of an Altitude Hold function would further reduce workload and improve overall

  14. Wall interaction effects for a full-scale helicopter rotor in the NASA Ames 80- by 120-foot wind tunnel

    Science.gov (United States)

    Shinoda, Patrick M.

    1994-01-01

    A full-scale helicopter rotor test was conducted in the NASA Ames 80- by 120-Foot Wind Tunnel with a four-bladed S-76 rotor system. This wind tunnel test generated a unique and extensive data base covering a wide range of rotor shaft angles-of-attack and rotor thrust conditions from 0 to 100 knots. Three configurations were tested: (1) empty tunnel; (2) test stand body (fuselage) and support system; and (3) fuselage and support system with rotor installed. Empty tunnel wall pressure data are evaluated as a function of tunnel speed to understand the baseline characteristics. Aerodynamic interaction effects between the fuselage and the walls of the tunnel are investigated by comparing wall, ceiling, and floor pressures for various tunnel velocities and fuselage angles-of-attack. Aerodynamic interaction effects between the rotor and the walls of the tunnel are also investigated by comparing wall, ceiling, and floor pressures for various rotor shaft angles, rotor thrust conditions, and tunnel velocities. Empty tunnel wall pressure data show good repeatability and are not affected by tunnel speed. In addition, the tunnel wall pressure profiles are not affected by the presence of the fuselage apart from a pressure shift. Results do not indicate that the tunnel wall pressure profiles are affected by the presence of the rotor. Significant changes in the wall, ceiling, and floor pressure profiles occur with changing tunnel speeds for constant rotor thrust and shaft angle conditions. Significant changes were also observed when varying rotor thrust or rotor shaft angle-of-attack. Other results indicate that dynamic rotor loads and blade motion are influenced by the presence of the tunnel walls at very low tunnel velocity and, together with the wall pressure data, provide a good indication of flow breakdown.

  15. Modelado de la cinética de secado de ñame (dioscorea rotundata en capa delgada

    Directory of Open Access Journals (Sweden)

    Everaldo Joaquín Montes Montes

    2008-05-01

    Full Text Available El secado de ñame en capa delgada, de las variedades 9811-089 y 9811-091, fue evaluado en un secador de la-boratorio tipo bandeja a temperaturas de 45, 55 y 70 °C y velocidad de aire promedio de 1 m/s, en el Laboratorio de Ingeniería Aplicada de la Universidad de Córdoba; las muestras fueron adecuadas en geometría de rodajas de radio 3,19 cm y espesor de 0,5 cm y láminas de 0,5x3x5 cm. Se evaluó el efecto de la temperatura, variedad y geometría en el tiempo de secado, empleando un diseño completamente al azar en arreglo factorial con tres facto-res: temperatura (45, 55 y 70 °C, geometría (rodajas y láminas y variedad (9811-089 y 9811-091, realizando tres repeticiones por tratamientoutilizando, dando como resultado una disminución en el tiempo de secado del 28,15% para la temperatura de 70 °C. Con los resultados obtenidos fueron construidas las curvas de secado, en las cuales se observó que este proceso tuvo lugar en el periodo decreciente, lo que evidencia que la difusión es el mecanismo que gobierna el secado de Dioscorea rotundata para las variedades estudiadas. Las curvas de secado fueron ajustadas a los modelos matemáticos de Page, difusión, Thompsom, Newton, Page modificado, Henderson y Pabis y el modelo logarítmico, determinando mediante el coeficiente de determinación (R2, error medio estimado (SE y desvío medio relativo (%P, que el modelo logarítmico es el que mejor describe el proceso de secado (R2 ≥ 99.17 y SE ≤ 0.0299.

  16. Problem-based learning (PBL): getting the most out of your students - their roles and responsibilities: AMEE Guide No. 84.

    Science.gov (United States)

    Bate, Emily; Hommes, Juliette; Duvivier, Robbert; Taylor, David C M

    2014-01-01

    This Guide discusses the considerable literature on the merits or shortcomings of Problem-based learning (PBL), and the factors that promote or inhibit it, when seen through the eyes of the student. It seems to be the case that PBL works best when students and faculty understand the various factors that influence learning and are aware of their roles; this Guide deals with each of the main issues in turn. One of the most important concepts to recognise is that students and Faculty share the responsibility for learning and there are several factors that can influence its success. They include student motivation for PBL and the various ways in which they respond to being immersed in the process. As faculty, we also need to consider the way in which the learning environment supports the students develop the habit of life-long learning, and the skills and attitudes that will help them become competent reflective practitioners. Each of these elements place responsibilities upon the student, but also upon the Faculty and learning community they are joining. Although all of the authors work in a European setting, where PBL is used extensively as a learning strategy in many medical schools, the lessons learned we suggest, apply more widely, and several of the important factors apply to any form of curriculum. This Guide follows on from a previous review in the AMEE Guides in Medical education series, which provided an overview of PBL and attempts to emphasise the key role that students have in mastering their subject through PBL. This should render the business of being a student a little less mystifying, and help faculty to see how they can help their students acquire the independence and mastery that they will need.

  17. Ames dwarf (Prop1(df)/Prop1(df)) mice display increased sensitivity of the major GH-signaling pathways in liver and skeletal muscle.

    Science.gov (United States)

    Miquet, Johanna G; Muñoz, Marina C; Giani, Jorge F; González, Lorena; Dominici, Fernando P; Bartke, Andrzej; Turyn, Daniel; Sotelo, Ana I

    2010-04-01

    Growth hormone (GH) is an anabolic hormone that regulates growth and metabolism. Ames dwarf mice are natural mutants for Prop1, with impaired development of anterior pituitary and undetectable levels of circulating GH, prolactin and TSH. They constitute an endocrine model of life-long GH-deficiency. The main signaling cascades activated by GH binding to its receptor are the JAK2/STATs, PI-3K/Akt and the MAPK Erk1/2 pathways. We have previously reported that GH-induced STAT5 activation was higher in Ames dwarf mice liver compared to non-dwarf controls. The aim of this study was to evaluate the principal components of the main GH-signaling pathways under GH-deficiency in liver and skeletal muscle, another GH-target tissue. Ames dwarf mice and their non-dwarf siblings were assessed. Animals were injected i.p. with GH or saline 15min before tissue removal. Protein content and phosphorylation of signaling mediators were determined by immunoblotting of tissue solubilizates. GH was able to induce STAT5 and STAT3 tyrosine phosphorylation in both liver and muscle, but the response was higher for Ames dwarf mice than for non-dwarf controls. When Erk1/2 activation was assessed in liver, only dwarf mice showed GH-induced phosphorylation, while in muscle no response to the hormone was found in either genotype. GH-induced Akt phosphorylation at Ser473 in liver was only detected in dwarf mice. In skeletal muscle, both normal and dwarf mice responded to a GH stimulus, although dwarf mice presented higher GH activation levels. The phosphorylation of GSK-3, a substrate of Akt, increased upon hormone stimulation only in dwarf mice in both tissues. In contrast, no differences in the phosphorylation of mTOR, another substrate of Akt, were observed after GH stimulus, either in normal or dwarf mice in liver, while we were unable to determine mTOR in muscle. Protein content of GH-receptor and of the signaling mediators studied did not vary between normal and dwarf animals in the assessed

  18. Reflections About the Role of Intellectuals in Latin America Reflexiones acerca del rol de los intelectuales en América Latina Reflexões sobre o papel dos intelectuais na América Latina

    Directory of Open Access Journals (Sweden)

    Judith Naidorf

    2010-10-01

    intellectual debate but to contribute to a not new but always applicable, which should be a breakthrough for each of our practices in the different social areas in which we daily work.

    En este trabajo nos proponemos abordar algunos aspectos teórico - conceptuales que contribuyan a la reflexión sobre la especificidad del papel del intelectual latinoamericano actual. Los aportes de diversos autores nos ayudarán a caracterizar un rol que se encuentra en permanente reformulación, análisis y discusión. La propuesta es retomar los desarrollos teóricos de la categoría de intelectual, desde Antonio Gramsci e Immanuel Wallerstein principalmente, pasando por sus momentos más intensos en la década del 60-70 con Sartre y Foucault en Europa. También se rescatan las contribuciones realizadas por Pierre Bourdieu, Sousa Santos y los aportes para América Latina de Fals Borda, Florestán Fernández, Octavio Ianni y Eliseo Verón, entre otros. Además se incluyen como ejemplos declaraciones del subcomandante Marcos para el EZLN y se hace referencia a los análisis realizados por Julio Gambina y Daniel Campione para el caso argentino. No es interés de este trabajo arribar a definiciones acabadas acerca de la función social del intelectual sino aportar a un debate no nuevo pero siempre vigente. Neste trabalho pretendemos abordar alguns aspectos teóricos-conceituais que contribuem para a reflexão sobre especificidade do papel do intelectual latino-americano atual. As contribuições de diferentes autores nos ajudam a caracterizar um papel que está constantemente sendo repensado, a análisado e discutido. A proposta é revisitar aos desenvolvimentos teóricos sobre o "intelectual" de Antonio Gramsci e Emanuel Wallerstein principalmente através dos debates mais intensos na década de 60-70 com Sartre e Foucault na Europa. Também se destacam as contribuições feitas por Pierre Bourdieu, Sousa Santos e contribuições desde América Latina de

  19. Model Deformation Measurements of Sonic Boom Models in the NASA Ames 9- by 7-Ft Supersonic Wind Tunnel

    Science.gov (United States)

    Schairer, Edward T.; Kushner, Laura K.; Garbeff, Theodore J.; Heineck, James T.

    2015-01-01

    The deformations of two sonic-boom models were measured by stereo photogrammetry during tests in the 9- by 7-Ft Supersonic Wind Tunnel at NASA Ames Research Center. The models were geometrically similar but one was 2.75 times as large as the other. Deformation measurements were made by simultaneously imaging the upper surfaces of the models from two directions by calibrated cameras that were mounted behind windows of the test section. Bending and twist were measured at discrete points using conventional circular targets that had been marked along the leading and trailing edges of the wings and tails. In addition, continuous distributions of bending and twist were measured from ink speckles that had been applied to the upper surfaces of the model. Measurements were made at wind-on (M = 1.6) and wind-off conditions over a range of angles of attack between 2.5 deg. and 5.0 deg. At each condition, model deformation was determined by comparing the wind-off and wind-on coordinates of each measurement point after transforming the coordinates to reference coordinates tied to the model. The necessary transformations were determined by measuring the positions of a set of targets on the rigid center-body of the models whose model-axes coordinates were known. Smoothly varying bending and twist measurements were obtained at all conditions. Bending displacements increased in proportion to the square of the distance to the centerline. Maximum deflection of the wingtip of the larger model was about 5 mm (2% of the semispan) and that of the smaller model was 0.9 mm (1% of the semispan). The change in wing twist due to bending increased in direct proportion to distance from the centerline and reached a (absolute) maximum of about -1? at the highest angle of attack for both models. The measurements easily resolved bending displacements as small as 0.05 mm and bending-induced changes in twist as small as 0.05 deg.

  20. Respuesta fisiológica del ñame espino (Dioscorea Rotundata Poir a las densidades de siembra

    Directory of Open Access Journals (Sweden)

    Dairo J. Pérez

    2015-12-01

    Full Text Available Esta investigación tuvo como objetivo estudiar la respuesta fisiológica del ñame espino (Dioscorea rotundata cv. brasilero en función del incremento de las densidades de siembra, bajo la oferta ambiental del Sinú medio. El estudio se llevó a cabo en la Universidad de Córdoba (Montería, Colombia, donde se evaluaron las densidades de siembra de 45.455, 30.303, 22.727 y 10.101 plantas/ha; bajo un diseño de Bloques Completos al Azar con tres repeticiones. Las variables de respuestas consideradas fueron la fotosíntesis neta (Pn, medida en tres etapas fenológicas (vegetativa, inicio y final de tuberización; y los índices de crecimiento: tasa absoluta de crecimiento (TAC, tasa de asimilación neta (TAN, tasa relativa de crecimiento (TRC e índice de área foliar (IAF. La Pn no varió entre las densidades de siembra (p≤0,05, pero después de la etapa vegetativa, se redujo en promedio un 19,14% para el inicio y final de la tuberización. La TAC y la TRC tuvieron similar tendencia, se incrementaron desde la etapa vegetativa, pero esta última se redujo al final del cultivo. La TAN comenzó a decrecer desde la etapa vegetativa con un leve incremento al final del ciclo. El IAF se incrementó significativamente a partir de la tuberización, para las densidades de siembra superiores a 10.101 plantas/ha, alcanzando valores entre 3,08 y 4,03. Se concluye que los índices de crecimiento a excepción del IAF y la Pn, no variaron entre las densidades de siembra, probablemente por la capacidad de la especie de regular su actividad fisiológica en función de la densidad de siembra.

  1. An Overview of Current Capabilities and Research Activities in the Airspace Operations Laboratory at NASA Ames Research Center

    Science.gov (United States)

    Prevot, Thomas; Smith, Nancy M.; Palmer, Everett; Callantine, Todd; Lee, Paul; Mercer, Joey; Homola, Jeff; Martin, Lynne; Brasil, Connie; Cabrall, Christopher

    2014-01-01

    The Airspace Operations Laboratory at NASA Ames conducts research to provide a better understanding of roles, responsibilities, and requirements for human operators and automation in future air traffic management (ATM) systems. The research encompasses developing, evaluating, and integrating operational concepts and technologies for near-, mid-, and far-term air traffic operations. Current research threads include efficient arrival operations, function allocation in separation assurance and efficient airspace and trajectory management. The AOL has developed powerful air traffic simulation capabilities, most notably the Multi Aircraft Control System (MACS) that is used for many air traffic control simulations at NASA and its partners in government, academia and industry. Several additional NASA technologies have been integrated with the AOL's primary simulation capabilities where appropriate. Using this environment, large and small-scale system-level evaluations can be conducted to help make near-term improvements and transition NASA technologies to the FAA, such as the technologies developed under NASA's Air Traffic Management Demonstration-1 (ATD-1). The AOL's rapid prototyping and flexible simulation capabilities have proven a highly effective environment to progress the initiation of trajectory-based operations and support the mid-term implementation of NextGen. Fundamental questions about accuracy requirements have been investigated as well as realworld problems on how to improve operations in some of the most complex airspaces in the US. This includes using advanced trajectory-based operations and prototype tools for coordinating arrivals to converging runways at Newark airport and coordinating departures and arrivals in the San Francisco and the New York metro areas. Looking beyond NextGen, the AOL has started exploring hybrid human/automation control strategies as well as highly autonomous operations in the air traffic control domain. Initial results

  2. When is a search not a search? A comparison of searching the AMED complementary health database via EBSCOhost, OVID and DIALOG.

    Science.gov (United States)

    Younger, Paula; Boddy, Kate

    2009-06-01

    The researchers involved in this study work at Exeter Health library and at the Complementary Medicine Unit, Peninsula School of Medicine and Dentistry (PCMD). Within this collaborative environment it is possible to access the electronic resources of three institutions. This includes access to AMED and other databases using different interfaces. The aim of this study was to investigate whether searching different interfaces to the AMED allied health and complementary medicine database produced the same results when using identical search terms. The following Internet-based AMED interfaces were searched: DIALOG DataStar; EBSCOhost and OVID SP_UI01.00.02. Search results from all three databases were saved in an endnote database to facilitate analysis. A checklist was also compiled comparing interface features. In our initial search, DIALOG returned 29 hits, OVID 14 and Ebsco 8. If we assume that DIALOG returned 100% of potential hits, OVID initially returned only 48% of hits and EBSCOhost only 28%. In our search, a researcher using the Ebsco interface to carry out a simple search on AMED would miss over 70% of possible search hits. Subsequent EBSCOhost searches on different subjects failed to find between 21 and 86% of the hits retrieved using the same keywords via DIALOG DataStar. In two cases, the simple EBSCOhost search failed to find any of the results found via DIALOG DataStar. Depending on the interface, the number of hits retrieved from the same database with the same simple search can vary dramatically. Some simple searches fail to retrieve a substantial percentage of citations. This may result in an uninformed literature review, research funding application or treatment intervention. In addition to ensuring that keywords, spelling and medical subject headings (MeSH) accurately reflect the nature of the search, database users should include wildcards and truncation and adapt their search strategy substantially to retrieve the maximum number of appropriate

  3. A New Way of Doing Business: Reusable Launch Vehicle Advanced Thermal Protection Systems Technology Development: NASA Ames and Rockwell International Partnership

    Science.gov (United States)

    Carroll, Carol W.; Fleming, Mary; Hogenson, Pete; Green, Michael J.; Rasky, Daniel J. (Technical Monitor)

    1995-01-01

    NASA Ames Research Center and Rockwell International are partners in a Cooperative Agreement (CA) for the development of Thermal Protection Systems (TPS) for the Reusable Launch Vehicle (RLV) Technology Program. This Cooperative Agreement is a 30 month effort focused on transferring NASA innovations to Rockwell and working as partners to advance the state-of-the-art in several TPS areas. The use of a Cooperative Agreement is a new way of doing business for NASA and Industry which eliminates the traditional customer/contractor relationship and replaces it with a NASA/Industry partnership.

  4. Analysis of aerodynamic measurements on a model wind turbine placed in the NASA-Ames tunnel. Contribution of ECN and TUD to IEA Wind Task XX

    Energy Technology Data Exchange (ETDEWEB)

    Schepers, J.G. [ECN Wind Energy, Petten (Netherlands); Van Rooij, R.P.J.O.M. [Delft University of Technology, Delft (Netherlands)

    2008-10-15

    In this report the most important contributions of ECN and DUT to IEA Wind Task XX are summarized. IEA Wind Task XX is an international cooperation between several parties from 7 countries coordinated by the National Renewable Energy Laboratory, NREL from the USA. The main aim of IEA Wind Task XX is to analyze the detailed aerodynamic measurements which were performed by NREL on a wind turbine placed in the large (24.4 x 36.6 m) NASA-Ames wind tunnel.

  5. Isospin transport phenomena and odd-even staggering in 84Kr+112,124Sn collisions at 35 AMeV

    Directory of Open Access Journals (Sweden)

    Piantelli S.

    2015-01-01

    Full Text Available Experimental results concerning isospin transport phenomena and odd-even staggering in Z and N distributions are presented. Data refer to 84Kr+112,124Sn collisions at 35AMeV and they were collected with a high resolution FAZIA telescope, able to isotopically resolve ions up to Z ∼ 20. Evidences of isospin diffusion and drift obtained from the /Z behaviour of the detected fragments are discussed. The odd-even staggering both in Z and N is compared with experimental data available in literature, finding that it shows a common trend in different reaction types.

  6. Isospin transport phenomena and odd-even staggering in 84Kr+112,124Sn collisions at 35 AMeV

    Science.gov (United States)

    Piantelli, S.; Casini, G.; Maurenzig, P. R.; Olmi, A.; Barlini, S.; Bini, M.; Carboni, S.; Pasquali, G.; Poggi, G.; Stefanini, A. A.; Valdré, S.; Bougault, R.; Bonnet, E.; Borderie, B.; Chbihi, A.; Frankland, J. D.; Gruyer, D.; Lopez, O.; Le Neindre, N.; Parlog, M.; Rivet, M.-F.; Vient, E.; Rosato, E.; Spadaccini, G.; Vigilante, M.; Bruno, M.; Marchi, T.; Morelli, L.; Cinausero, M.; Degerlier, M.; Gramegna, F.; Kozik, T.; Twarog, T.; Alba, R.; Maiolino, C.; Santonocito, D.

    2015-04-01

    Experimental results concerning isospin transport phenomena and odd-even staggering in Z and N distributions are presented. Data refer to 84Kr+112,124Sn collisions at 35AMeV and they were collected with a high resolution FAZIA telescope, able to isotopically resolve ions up to Z ˜ 20. Evidences of isospin diffusion and drift obtained from the /Z behaviour of the detected fragments are discussed. The odd-even staggering both in Z and N is compared with experimental data available in literature, finding that it shows a common trend in different reaction types.

  7. Mutagenic Potential of 2-(E)-Hydroxyiminomethyl-3-methyl-1-(1,2,2- trimethylpropyloxymethyl)imidazolium Chloride in the Ames Salmonella/Mammalian Microsome Mutagenicity Test

    Science.gov (United States)

    1988-11-01

    and the methods for strain validacion are given in the LAIR SOP, C)P-STX-l (2). Test Format 2- (E) -HYDROXYIMINOMETHYL-3-METHYL-l- (1,2,2...Ames Sahnonella/Mammalian Microsome Mutagenicity Test St,-ven K. Sano, BA, SGT, USA and Don W. Korte, Jr., PhD, MAJ, MSC GENEC TOXICOLOGY BRANCH...tirncithl.I p ropyloxylllctllyl)ililidalzolitiu Chloride ini the Anies Salm’osel/a/Maxiinailiaui N-icroso ,oe lakgenicity Test (Toxicology Series 124

  8. Report of the Interagency Optical Network Testbeds Workshop 2 September 12-14, 2006 NASA Ames Research Center

    Energy Technology Data Exchange (ETDEWEB)

    Joe Mambretti Richard desJardins

    2006-05-01

    A new generation of optical networking services and technologies is rapidly changing the world of communications. National and international networks are implementing optical services to supplement traditional packet routed services. On September 12-14, 2005, the Optical Network Testbeds Workshop 2 (ONT2), an invitation-only forum hosted by the NASA Research and Engineering Network (NREN) and co-sponsored by the Department of Energy (DOE), was held at NASA Ames Research Center in Mountain View, California. The aim of ONT2 was to help the Federal Large Scale Networking Coordination Group (LSN) and its Joint Engineering Team (JET) to coordinate testbed and network roadmaps describing agency and partner organization views and activities for moving toward next generation communication services based on leading edge optical networks in the 3-5 year time frame. ONT2 was conceived and organized as a sequel to the first Optical Network Testbeds Workshop (ONT1, August 2004, www.nren.nasa.gov/workshop7). ONT1 resulted in a series of recommendations to LSN. ONT2 was designed to move beyond recommendations to agree on a series of “actionable objectives” that would proactively help federal and partner optical network testbeds and advanced research and education (R&E) networks to begin incorporating technologies and services representing the next generation of advanced optical networks in the next 1-3 years. Participants in ONT2 included representatives from innovative prototype networks (Panel A), basic optical network research testbeds (Panel B), and production R&D networks (Panels C and D), including “JETnets,” selected regional optical networks (RONs), international R&D networks, commercial network technology and service providers (Panel F), and senior engineering and R&D managers from LSN agencies and partner organizations. The overall goal of ONT2 was to identify and coordinate short and medium term activities and milestones for researching, developing, identifying

  9. Ajakirjanik teeb algupärast indiaanimuusikali / Verni Leivak

    Index Scriptorium Estoniae

    Leivak, Verni, 1966-

    2004-01-01

    Kanal2 uudistereporter Üllar Purre ja tema kaks kaaslast bändist Üle Saja laulavad linti omakirjutatud rokkooperit "Vikerkaar ehk Mata mu süda Wounded Knees". Lisaks kommentaar "Muusikaliprofid arvavad"

  10. Taska teeb Venezuela seebi eesti moodi / Verni Leivak

    Index Scriptorium Estoniae

    Leivak, Verni, 1966-

    2008-01-01

    Produtsent Kristian Taska ostis ära Venezuela seebiooperi "Lorenzo naine", et valmistada Kanal Spordis näitamiseks Eesti oludele mugandatud "Kalevi naised" (lavastaja Ingomar Vihmar, osades Maria Avdjuško, Andrus Vaarik, Jan Uuspõld, Anne Reemann)

  11. Maian Kärmas teeb alguse Jõulujazzile Tartus / Lia Eller

    Index Scriptorium Estoniae

    Eller, Lia

    2003-01-01

    Jõulujazzi üritustest Tartus: Maian Kärmase kontserdist Sadamateatris "Tuigutuled", Arne Oidi 75. sünniaastapäeva tähistavast kontserdist Vanemuise kontserdisaalis 4. dets., ameerika ansambli Gold Company Sextet kontserdist 15. detsembril

  12. Mees teab, mis mees teeb / Illimar Truverk ; intervjueerinud Signe Sillasoo

    Index Scriptorium Estoniae

    Truverk, Illimar, 1967-

    2011-01-01

    Illimar Truverk räägib oma tööst, konkurssidel osalemisest, linnaarhitekti ja riigiarhitekti ametikohast, riigihangete paremast korraldamisest. Loetletud olulisemad tööd. Pikemalt Shanghai EXPO 2010 Eesti paviljonist

  13. Washington teeb sõjajärgseid plaane / Neeme Raud

    Index Scriptorium Estoniae

    Raud, Neeme, 1969-

    2003-01-01

    Ameerika Ettevõtluse Instituudis toimunud "musta kohvi briifingul" avaldasid mitmed USA konservatiivsed ideoloogid rahulolu Iraagi sõja kulgemisega ja tegid sõjajärgseid plaane. President George W. Bushi visioonist. "Uue Ameerika sajandi" programmist

  14. Armastus teeb tugevaks / Marina Laikjõe ; interv. Verni Leivak

    Index Scriptorium Estoniae

    Laikjõe, Marina, 1967-

    2008-01-01

    Turismifirma Tez Tour tegevjuht ning reisifirma Travel-In juht Marina Laikjõe vastab küsimustele, mis puudutavad tema tegevust ja karjääri turisminduses, suhteid kolleegidega ning perekonna toetust raske haigusega võitlemise ajal. Kommenteerivad Reet Kivi, Tiit Pärnik. Lisa: Marina Laikjõe

  15. Aju teeb raalile ära / Kristjan Port

    Index Scriptorium Estoniae

    Port, Kristjan

    2007-01-01

    IBM koos Nevada Ülikooliga otsustas simuleerida arvutil ajutegevust. Spetsiaalselt loodud tarkvara pidi järele aimama närvirakkude tööd. Raal jõudis töötada umbes 10 minutit, kuni ülesande keerukus peatas edasise tegevuse. Superarvuti suutlikkuseks oli pool hiire aju võimekusest

  16. Film teeb USA valmistumise Iraagi okupatsiooniks maatasa / Neeme Raud

    Index Scriptorium Estoniae

    Raud, Neeme, 1969-

    2007-01-01

    Dokumentaalfilm "Lõppu ei ole näha" ("No End in Sight") : autor ja režissöör professor Charles Ferguson : Ameerika Ühendriigid 2007. Lisa: USA vead Iraagis. Vt. samas: Sunniidid lahkusid Iraagi valitsusest

  17. "Beverly Hills 90210" : kes mida teeb / Tiina Lepiste

    Index Scriptorium Estoniae

    Lepiste, Tiina

    2003-01-01

    Aaron Spellingu produtseeritud ja 2000. aastal lõpetatud menuseriaalis "Beverly Hills 90210" osalenud näitlejate edaspidisest elust seoses plaaniga teha täispikk mängufilm "10 Year High School Reunion"

  18. Kas inflatsioon teeb Eestist euroliidu Zimbabwe? / Margus Sanglepp

    Index Scriptorium Estoniae

    Sanglepp, Margus, 1967-

    2007-01-01

    Eesti valitsus ei ole inflatsiooni pidurdamiseks abinõusid kasutusele võtnud. Lätis ei ole valitsuse püüe ohjeldada inflatsiooni tulemusi andnud. Vt. samas: Märten Ross. Riigi võimalused inflatsiooni mõjutamiseks

  19. Mis ikkagi teeb Eestist Uganda? / Marja-Liisa Alop

    Index Scriptorium Estoniae

    Alop, Marja-Liisa

    2006-01-01

    Eesti üliõpilaskondade liidu juhatuse aseesimees M.-L. Alop kirjutab vastuse M. Heidmetsa artiklile 6. jaan. Eesti Päevalehes "Eestis nagu Ugandas", kus tõstatati Eestis üldise õppemaksu kehtestamise vajadus, mis vähendab vähem kindlustatute võimalusi kõrgharidust omandada

  20. Soomlane teeb Eestis iga kuu jõuluvana / Vilja Kohler

    Index Scriptorium Estoniae

    Kohler, Vilja, 1966-

    2008-01-01

    Soomlased Esa Tasanen ja Marja Korpimäki jagavad Alatskivil ja Pala vallas humanitaarabi. Küsimusele, kas Eesti inimesed vajavad veel humanitaarabi, vastavad Maret Maripuu, Ene Sõber, Vladimir Shokman, Aime Koger

  1. Merca teeb Metsateatris mereröövlit / Aigi Viira

    Index Scriptorium Estoniae

    Viira, Aigi

    2004-01-01

    1. aug. esietendus Saare Metsateatris (35 km Tartust) koguperetükk "Silver Ükssilm ja admirali vanne" H. Väli samanimelise teose järgi, lavastaja M. Tikk. Lisaks asjaarmastajatele mängivad ka Vanemuise näitlejad, sealhulgas M. Jääger peaosalist

  2. Lasteraamatukoguhoidja teeb loomingulist tööd / Nelli Orgmaa

    Index Scriptorium Estoniae

    Orgmaa, Nelli

    2010-01-01

    Lasteraamatukogude tööst 2009. aastal, märksõnadeks töö väikelastega, koostöö partneritega ja Edgar Valteri 80. sünniaastapäeva tähistamine. Sisaldab maakondade lugejate, külastuste ja laenutuste statistikat

  3. DILL teeb Tallinna kolmandas maailmas tuntuks / Virve Liivanõmm

    Index Scriptorium Estoniae

    Liivanõmm, Virve

    2010-01-01

    DILL on Euroopa kolme ülikooli (Oslo, Parma, Tallinna) ingliskeelne magistriõppekava peamiselt kolmandatest riikidest tudengitele, mida Euroopa Liit rahastab Erasmus Mundus programmi raames. Eestis koordineerib ja juhendab enamikku Tallinnas tehtavatest magistritöödest TLÜ infoteaduste instituudi lektor Sirje Virkus

  4. Mark Soosaar teeb filmi Siiri Sisaskist / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2002-01-01

    Režissöör jutustab oma reisist lauljatar Siiri Sisaskiga Mongooliasse, et filmida seal episoode dokumentaalfilmi "Siiri, hääl maa ja taeva vahel" jaoks. Samuti tuleb jutuks dokumentaalfilmide näitamine kinos ja mõned režissööri elupõhimõtted. Ka : Teleleht nr. 4, lk. 6-8

  5. Käsitöö teeb asjad paremaks / Karin Paulus

    Index Scriptorium Estoniae

    Paulus, Karin, 1975-

    2007-01-01

    Eesti ja inglise kunstnike ühisnäitusest "Minu maailm : uus subjektiivsus kaasaegses disainis" Eesti Tarbekunsti- ja Disainimuuseumis. Kuraatorid Emily Campell, Andree Cook, Kai Lobjakas. Eksponeeritakse Annike Laigo, Krista Leesi, Ülle Jehe, Kärt Ojavee töid. Inglismaad esindavad 7 kunstnikku, lähemalt Danny Browni ja Alison Willoughby töödest

  6. Citigroupi soovitus teeb Hansapanga aktsia kuulsaks / Annika Matson

    Index Scriptorium Estoniae

    Matson, Annika, 1976-

    2005-01-01

    Maailma suurim pank Citigroup soovitab osta Hansapanga aktsiaid ning kiidab panga kiiret kasvu regioonis ja esmaklassilist juhtimistiimi. Kommenteerivad: Rain Lõhmus, Jüri Mõis, Heldur Meerits. Vt. samas: Ka Leedu Hansabankas tõi hea uudise; Tõnis Oja. Hansapank Wall Streeti suurtegija huviorbiidis

  7. Uinunud Alice'i toas teeb imesid lavamaagia / Jaanus Kaasik

    Index Scriptorium Estoniae

    Kaasik, Jaanus

    2004-01-01

    7. veebr. esietendus Vanemuises tantsulavastus "Alice imedemaal". Etendus põhineb briti kirjaniku L. Carrolli samanimelisel lasteraamatul, koreograaf M. Murdmaa, kunstnik K. Jancis ja muusika on kirjutanud ungari helilooja S. Kall̤s, Alice'i osa tantsib korealanna Hye Min Kim

  8. Läti film teeb kadedaks / Mart Rummo

    Index Scriptorium Estoniae

    Rummo, Mart

    2001-01-01

    Kinomajas Läti filmipäevadel näidatud filmidest. Pikemalt Romualds Piparsi dokumentaalfilmist "Elu vabadusele" ning režissööri lühimängufilmist "Pulm". Autor küsib ka Läti Riikliku Filmikeskuse direktorilt Bruno Asèuksilt läti täispika mängufilmi "Ohtlik suvi" menu saladust kodumaal

  9. Kui Thatcher kiidab ja Pinochet teeb pai / Erik Terk

    Index Scriptorium Estoniae

    Terk, Erik

    2006-01-01

    Thatcheri ja Reagani nimedega seostatav neoliberaalne revolutsioon on saanud piisavalt vanaks, et kujundada pilt, mis toimus ja kuhu see meid viib. See ongi uue neoliberalismiraamatu David Harvey. A Brief History of Neoliberalism aineks

  10. No-Big-Silence teeb klubituuri / Urmas Hännile

    Index Scriptorium Estoniae

    Hännile, Urmas

    2009-01-01

    Rockansamblist No-Big-Silence ja dark-popansamblist Sinine, nende kontsertttuurist mööda Eestimaad, tutvustamisel bändide uued albumid (No-Big-Silence "Starstealer" ja Sinine "Butterflies"), Pärnus on kontsert 24. oktoobril klubis Sugar

  11. IKEA teeb panuse Briti ja Venemaa turule / Tõnis Arnover

    Index Scriptorium Estoniae

    Arnover, Tõnis, 1952-

    2006-01-01

    Rootsi mööblikontsern IKEA laiendab müügipindu Suurbritannias, Venemaal ja Jaapanis. Diagramm: Suurbritannia turg IKEA-le ka praegu tähtsuselt teine. Vt. samas: IKEA firmakultuur ei näe ette juhtivtöötajate poputamist

  12. "Tulnukas" teeb jõmmist kunstiteose / Keiu Virro

    Index Scriptorium Estoniae

    Virro, Keiu

    2007-01-01

    Tallinna Ülikooli filmi ja video õppetoolis Rasmus Merivoo lõputööna valminud filmist "Tulnukas ehk Valdise päästmine 11 osas", mis kogub internetis vaatajaid ning on muutumas kultusfilmiks. 22-minutiline lühifilm portreteerib Eestis laialt levinud subkultuuri - jõmlust ja rullnoklust

  13. NASA Ames DEVELOP Interns Collaborate with the South Bay Salt Pond Restoration Project to Monitor and Study Restoration Efforts using NASA's Satellites

    Science.gov (United States)

    Newcomer, Michelle E.; Kuss, Amber Jean; Nguyen, Andrew; Schmidt, Cynthia L.

    2012-01-01

    In the past, natural tidal marshes in the south bay were segmented by levees and converted into ponds for use in salt production. In an effort to provide habitat for migratory birds and other native plants and animals, as well as to rebuild natural capital, the South Bay Salt Pond Restoration Project (SBSPRP) is focused on restoring a portion of the over 15,000 acres of wetlands in California's South San Francisco Bay. The process of restoration begins when a levee is breached; the bay water and sediment flow into the ponds and eventually restore natural tidal marshes. Since the spring of 2010 the NASA Ames Research Center (ARC) DEVELOP student internship program has collaborated with the South Bay Salt Pond Restoration Project (SBSPRP) to study the effects of these restoration efforts and to provide valuable information to assist in habitat management and ecological forecasting. All of the studies were based on remote sensing techniques -- NASA's area of expertise in the field of Earth Science, and used various analytical techniques such as predictive modeling, flora and fauna classification, and spectral detection, to name a few. Each study was conducted by a team of aspiring scientists as a part of the DEVELOP program at Ames.

  14. Thermo Physics Facilities Branch Brochure ARC Jet Complex Fact Sheets, Hypervelocity Free-Flight Aerodynamic Facility Fact Sheets, Ames Vertical Gun Range Fact Sheets

    Science.gov (United States)

    Fretter, E. F. (Editor); Kuhns, Jay (Editor); Nuez, Jay (Editor)

    2003-01-01

    The Ames Arc Jet Complex has a rich heritage of over 40 years in Thermal Protection System (TPS) development for every NASA Space Transportation and Planetary program, including Apollo, Space Shuttle, Viking, Pioneer-Venus, Galileo, Mars Pathfinder,Stardust, NASP,X-33,X-34,SHARP-B1 and B2,X-37 and Mars Exploration Rovers. With this early TPS history came a long heritage in the development of the arc jet facilities. These are used to simulate the aerodynamic heating that occurs on the nose cap, wing leading edges and on other areas of the spacecraft requiring thermal protection. TPS samples have been run in the arc jets from a few minutes to over an hour,from one exposure to multiple exposures of the same sample, in order t o understand the TPS materials response to a hot gas flow environment (representative of real hyperthermal environments experienced in flight). The Ames Arc l e t Complex is a key enabler for customers involved in the three major areas of TPS development: selection, validation, and qualification. The arc jet data are critical for validating TPS thermal models, heat shield designs and repairs, and ultimately for flight qualification.

  15. Comparative Evaluation of Biochemical Changes in Tomato (Lycopersicon esculentumMill.) Infected byAlternaria alternataand Its Toxic Metabolites (TeA, AOH, and AME).

    Science.gov (United States)

    Meena, Mukesh; Zehra, Andleeb; Dubey, Manish K; Aamir, Mohd; Gupta, Vijai K; Upadhyay, Ram S

    2016-01-01

    In the present study, we have evaluated the comparative biochemical defense response generated against Alternaria alternata and its purified toxins viz. alternariol (AOH), alternariol monomethyl ether (AME), and tenuazonic acid (TeA). The necrotic lesions developed due to treatment with toxins were almost similar as those produced by the pathogen, indicating the crucial role of these toxins in plant pathogenesis. An oxidative burst reaction characterized by the rapid and transient production of a large amount of reactive oxygen species (ROS) occurs following the pathogen infection/toxin exposure. The maximum concentration of hydrogen peroxide (H 2 O 2 ) produced was reported in the pathogen infected samples (22.2-fold) at 24 h post inoculation followed by TeA (18.2-fold), AOH (15.9-fold), and AME (14.1-fold) in treated tissues. 3,3'- Diaminobenzidine staining predicted the possible sites of H 2 O 2 accumulation while the extent of cell death was measured by Evans blue dye. The extent of lipid peroxidation and malondialdehyde (MDA) content was higher (15.8-fold) at 48 h in the sample of inoculated leaves of the pathogen when compared to control. The cellular damages were observed as increased MDA content and reduced chlorophyll. The activities of antioxidative defense enzymes increased in both the pathogen infected as well as toxin treated samples. Superoxide dismutase (SOD) activity was 5.9-fold higher at 24 h post inoculation in leaves followed by TeA (5.0-fold), AOH (4.1-fold) and AME (2.3-fold) treated leaves than control. Catalase (CAT) activity was found to be increased upto 48 h post inoculation and maximum in the pathogen challenged samples followed by other toxins. The native PAGE results showed the variations in the intensities of isozyme (SOD and CAT) bands in the pathogen infected and toxin treated samples. Ascorbate peroxidase (APx) and glutathione reductase (GR) activities followed the similar trend to scavenge the excess H 2 O 2 . The reduction in CAT

  16. Elastic and inelastic scattering of 9,11 Li + Si at backward angles in the energy range (9.5 - 25) AMeV

    International Nuclear Information System (INIS)

    Petrascu, M.; Bordeanu, C.; Isbasescu, A.; Mihai, I.; Giurgiu, M.

    1997-01-01

    Recently, an inclusive fusion experiment of 9,11 Li projectiles with Si targets, in the energy range (9.5 - 25) AMeV has been performed at Riken Ring Cyclotron-Japan using, for the detection of the fusion products, an ionization chamber, MUSIC, built in NIPNE-HH, Bucharest. In this experiment, the contribution of elastic and inelastic scattering, at forward detection angles is eliminated through the experimental set-up. For a clear investigation of the fusion process, the estimation of elastic and inelastic scattering at backward angles, between 80 angle - 180 angle was considered necessary. This estimation was made by the coupled channels computer code ECIS. ECIS is an iterative method, the first iteration of this procedure being DWBA. In the analysis of elastic and inelastic scattering of 9,11 Li projectile on Si target we assumed that the incident 9 Li and 11 Li waves are diffracted by an optical potential with an Woods-Saxon geometry. The adopted optical potential is given. For the depth of the real and imaginary volume terms we used values dependent on projectile energy and target mass number. These values have been chosen in good agreement with a semi-microscopic model with a double-folding potential. The set of optical parameters selected for the system 9,11 Li (13 AMeV) + Si is given. The presence of neutron halo of 11 Li nucleus was taken into account by using adjusted values for the parameters r R and a R . The 28 Si nucleus is considered a rigid rotor, including the couplings involving the ground state and a first to excited states. The quadrupole deformation parameter was β 2 = - 0.24. The results for the scattering of 11 Li projectile on Si target at 13 AMeV energy are given with the parameters R match , I and J max taken from the Monte Carlo simulations with PACE code. We found that the contribution of elastic and inelastic scattering for background angles, between 80 angle - 180 angle is under 2%. The contribution of a inelastic scattering taken

  17. Assessing the cytotoxic and mutagenic effects of secondary metabolites produced by several fungal biological control agents with the Ames assay and the VITOTOX(®) test.

    Science.gov (United States)

    Kouvelis, Vassili N; Wang, Chengshu; Skrobek, Anke; Pappas, Katherine M; Typas, Milton A; Butt, Tariq M

    2011-05-18

    The potential genotoxic effects of several pure secondary metabolites produced by fungi used as biological control agents (BCAs) were studied with the Ames Salmonella/microsome mutagenicity assay and the Vitotox test, with and without metabolic activation. A complete set of Salmonella tester strains was used to avoid false negative results. To detect possible mutagenic and/or cytotoxic effects of fungal secondary metabolites due to synergistic action, crude extracts and fungal cell extracts of the BCAs were also examined. Although the sensitivity of the methods varied depending on the metabolite used, clearly no genotoxicity was observed in all cases. The results of the two assays are discussed in the light of being used in a complementary fashion for a convincing risk-assessment evaluation of fungal BCAs and their secondary metabolites. 2011 Elsevier B.V. All rights reserved.

  18. The NASA Ames PAH IR Spectroscopic Database: Computational Version 3.00 with Updated Content and the Introduction of Multiple Scaling Factors

    Science.gov (United States)

    Bauschlicher, Charles W., Jr.; Ricca, A.; Boersma, C.; Allamandola, L. J.

    2018-02-01

    Version 3.00 of the library of computed spectra in the NASA Ames PAH IR Spectroscopic Database (PAHdb) is described. Version 3.00 introduces the use of multiple scale factors, instead of the single scaling factor used previously, to align the theoretical harmonic frequencies with the experimental fundamentals. The use of multiple scale factors permits the use of a variety of basis sets; this allows new PAH species to be included in the database, such as those containing oxygen, and yields an improved treatment of strained species and those containing nitrogen. In addition, the computed spectra of 2439 new PAH species have been added. The impact of these changes on the analysis of an astronomical spectrum through database-fitting is considered and compared with a fit using Version 2.00 of the library of computed spectra. Finally, astronomical constraints are defined for the PAH spectral libraries in PAHdb.

  19. A Tale of Two Small Business Grants: The Best of Times, the Worst of Times from the NASA Ames Small Business Innovative Research (SBIR) Program

    Science.gov (United States)

    Kojiro, Daniel R.; Lee, Geoffrey S.

    2006-01-01

    The purposes of the SBIR Program are to: stimulate technological innovation in the private sector; strengthen the role of Small Business Concerns (SBCs) in meeting Federal research and development needs; increase the commercial application of these research results; and encourage participation of socially and economically disadvantaged persons and women-owned small businesses. The process can be highly rewarding, providing the small business with resources to pursue research and development with a focus on providing NASA with new and advanced capabilities. We present two examples of how the NASA Ames SBIR Program has addressed these purposes, nurturing innovative ideas from small, businesses into commercially viable products that also address analytical needs in space research. These examples, from the Science Instruments for Conducting Solar System Exploration Subtopic, describe the journey from innovative concept to analytical instrument, one successful and one hampered by numerous roadblocks (including some international intrigue}.

  20. Estrategias de visibilización de la diáspora africana en América Latina y el Caribe durante el nuevo milenio

    Directory of Open Access Journals (Sweden)

    María José Becerra

    2008-01-01

    Full Text Available Las sociedades de América Latina y el Caribe presentan una complejidad fruto de un pasado histórico, en donde se entrecruzan diferentes formas de explotación sobre una población heterogénea. Consecuentemente, el ejercicio de la dominación construido por los grupos hegemónicos marginó a las mayorías sociales y particularmente a los descendientes de la diáspora forzada africana. La conformación de los Estados nacionales decimonónicos, lejos de revertir la problemática, instaló una nueva dicotomía entre los “civilizados” y los “bárbaros”, coartando con ello la posibilidad de gestar un espacio integrador de las sociedades americanas de carácter multicultural. Desde 2000, estas acciones han logrado que organizaciones internacionales presten atención a la problemática de los afrodescendientes en América Latina y el Caribe apoyando y estimulando la búsqueda de nuevas estrategias, ahora a nivel continental e interregional. En este sentido nos proponemos realizar una reseña de las actividades que los afrodesceninetes vienen realizando en pos de ser visibilizados. Visibilidad que no sólo tiende a mejorar su situación particular, sino también a que las sociedades americanas sean más democráticas y pluralistas.

  1. Die aktive Beteiligung deutschsprachiger Länder an den Konferenzen der Association for Medical Education in Europe (AMEE zwischen 2005 und 2013: Spiegelbild der Entwicklung der medizinischen Ausbildungsforschung?

    Directory of Open Access Journals (Sweden)

    Raes, Patricia

    2014-08-01

    Full Text Available [english] Objectives: Medical education is gaining in significance internationally. A growing interest in the field has been observed in German-speaking countries (Austria, Germany, Switzerland since the early 2000s. This interest is not, however, reflected in an increase in the number of publications on medical education of German-speaking authors in international professional journals. The following investigation examines the potential use of active participant numbers of German-speaking researchers at AMEE conferences as a means of measuring said development. Methods: The AMEE conference proceedings from the categories and from the years 2005-2013 were examined for evidence of Austrian, German and Swiss participation. The abstracts were subsequently analysed in terms of content and categorised according to , and .Results: Of the 9,446 analysed abstracts, 549 contributions show at least one first, last or co-author from Austria, Germany or Switzerland. The absolute number of contributions per conference varied between 44 in 2010 and 77 in 2013. The percentage fluctuated between 10% in 2005 and 4.1% in 2010. From the year 2010 onwards, however, participation increased continually. The research was predominantly descriptive (62.7%. Studies on fundamental questions of teaching and learning ( were less frequent (4.0%. For the most part, quantitative methods (51.9% were implemented in addressing subjects such as (33%, (22.4% or (14.4%. The study population was usually comprised of students (52.5%.Conclusions: The number of contributions from Austria, Germany and Switzerland peak at the beginning and at the end of the evaluated period of time. A continual increase in active participation since 2005 was not observed. These observations do not reflect the actual increase of interest in medical education research in German-speaking countries.

  2. Citrus aurantium (bitter orange) extract: Safety assessment by acute and 14-day oral toxicity studies in rats and the Ames Test for mutagenicity.

    Science.gov (United States)

    Deshmukh, N S; Stohs, S J; Magar, C C; Kadam, S B

    2017-11-01

    The primary active constituent in bitter orange extract (BOE) is p-synephrine. This study assessed the safety of a BOE standardized to 50% p-synephrine following short-term exposure to rats and by the Ames Test. Following 5000 mg/kg of the extract orally to female rats all animals survived. Administration at 2000 mg/kg to female rats for four days yielded no signs of toxicity. Five male and five female rats were administered the BOE at 0, 250, 500, 1000 and 2000 mg/kg/day for 14 days. No significant effects were observed at any dose with respect to body weights, food intake, absolute and relative organ weights, hematology, clinical chemistry, and pathology. Two male rats died after 2000 mg/kg with gastrointestinal impaction at necropsy. During week two of 1000 mg/kg and 2000 mg/kg/day, rats exhibited transient signs of repetitive burrowing of heads in the bedding material (hypoactivity) for about 15 and 45 min, respectively. The no-observed-effect-level (NOEL) was 500 mg/kg/day. The mutagenic potential was assessed at and up to the limit dose of 5000 μg/plate in a Salmonella typhimurium reverse mutation (Ames) test, performed in duplicate as a pre-incubation assay in the presence and absence of metabolic activation (S9). The BOE did not induce an increase in the frequency of revertant colonies at any dose in the five tester strains, and was therefore non-mutagenic. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Inhalational anthrax (Ames aerosol) in naïve and vaccinated New Zealand rabbits: characterizing the spread of bacteria from lung deposition to bacteremia.

    Science.gov (United States)

    Gutting, Bradford W; Nichols, Tonya L; Channel, Stephen R; Gearhart, Jeffery M; Andrews, George A; Berger, Alan E; Mackie, Ryan S; Watson, Brent J; Taft, Sarah C; Overheim, Katie A; Sherwood, Robert L

    2012-01-01

    There is a need to better understand inhalational anthrax in relevant animal models. This understanding could aid risk assessment, help define therapeutic windows, and provide a better understanding of disease. The aim here was to characterize and quantify bacterial deposition and dissemination in rabbits following exposure to single high aerosol dose (> 100 LD(50)) of Bacillus anthracis (Ames) spores immediately following exposure through 36 h. The primary goal of collecting the data was to support investigators in developing computational models of inhalational anthrax disease. Rabbits were vaccinated prior to exposure with the human vaccine (Anthrax Vaccine Adsorbed, AVA) or were sham-vaccinated, and were then exposed in pairs (one sham and one AVA) so disease kinetics could be characterized in equally-dosed hosts where one group is fully protected and is able to clear the infection (AVA-vaccinated), while the other is susceptible to disease, in which case the bacteria are able to escape containment and replicate uncontrolled (sham-vaccinated rabbits). Between 4-5% of the presented aerosol dose was retained in the lung of sham- and AVA-vaccinated rabbits as measured by dilution plate analysis of homogenized lung tissue or bronchoalveolar lavage (BAL) fluid. After 6 and 36 h, >80% and >96%, respectively, of the deposited spores were no longer detected in BAL, with no detectable difference between sham- or AVA-vaccinated rabbits. Thereafter, differences between the two groups became noticeable. In sham-vaccinated rabbits the bacteria were detected in the tracheobronchial lymph nodes (TBLN) 12 h post-exposure and in the circulation at 24 h, a time point which was also associated with dramatic increases in vegetative CFU in the lung tissue of some animals. In all sham-vaccinated rabbits, bacteria increased in both TBLN and blood through 36 h at which point in time some rabbits succumbed to disease. In contrast, AVA-vaccinated rabbits showed small numbers of CFU in

  4. Stereo Photogrammetry Measurements of the Position and Attitude of a Nozzle-Plume/Shock-Wave Interaction Model in the NASA Ames 9- by 7-Ft Supersonic Wind Tunnel

    Science.gov (United States)

    Schairer, Edward T.; Kushner, Laura K.; Drain, Bethany A.; Heineck, James T.; Durston, Donald A.

    2017-01-01

    Stereo photogrammetry was used to measure the position and attitude of a slender body of revolution during nozzle-plume/shock-wave interaction tests in the NASA Ames 9- by 7-Ft Supersonic Wind Tunnel. The model support system was designed to allow the model to be placed at many locations in the test section relative to a pressure rail on one sidewall. It included a streamwise traverse as well as a thin blade that offset the model axis from the sting axis. With these features the support system was more flexible than usual resulting in higher-than-usual uncertainty in the position and attitude of the model. Also contributing to this uncertainty were the absence of a balance, so corrections for sting deflections could not be applied, and the wings-vertical orientation of the model, which precluded using a gravity-based accelerometer to measure pitch angle. Therefore, stereo photogrammetry was chosen to provide independent measures of the model position and orientation. This paper describes the photogrammetry system and presents selected results from the test.

  5. Mutagens from the cooking of food. III. Survey by Ames/Salmonella test of mutagen formation in secondary sources of cooked dietary protein.

    Science.gov (United States)

    Bjeldanes, L F; Morris, M M; Felton, J S; Healy, S; Stuermer, D; Berry, P; Timourian, H; Hatch, F T

    1982-08-01

    A survey of mutagen formation during the cooking of a variety of protein-rich foods that are minor sources of protein intake in the American diet is reported (see Bjeldanes, Morris, Felton et al. (1982) for survey of major protein foods). Milk, cheese, tofu and organ meats showed negligible mutagen formation except following high-temperature cooking for long periods of time. Even under the most extreme conditions, tofu, cheese and milk exhibited fewer than 500 Ames/Salmonella typhimurium revertants/100 g equivalents (wet weight of uncooked food), and organ meats only double that amount. Beans showed low mutagen formation after boiling and boiling followed by frying (with and without oil). Only boiling of beans followed by baking for 1 hr gave appreciable mutagenicity (3650 revertants/100g equivalents). Seafood samples gave a variety of results: red snapper, salmon, trout, halibut and rock cod all gave more than 1000 revertants/100 g wet weight equivalents when pan-fried or griddle-fried for about 6 min/side. Baked or poached rock and deep-fried shrimp showed no significant mutagen formation. Broiled lamb chops showed mutagen formation similar to that in red meats tested in the preceding paper: 16,000 revertants/100 g equivalents. These findings show that as measured by bioassay in S. typhimurium, most of the foods that are minor sources of protein in the American diet are also minor sources of cooking-induced mutagens.

  6. A preliminary Ames fluctuation assay assessment of the genotoxicity of drinking water that has been solar disinfected in polyethylene terephthalate (PET) bottles.

    Science.gov (United States)

    Ubomba-Jaswa, Eunice; Fernández-Ibáñez, Pilar; McGuigan, Kevin G

    2010-12-01

    Though microbially safe, concerns have been raised about the genotoxic/mutagenic quality of solar-disinfected drinking water, which might be compromised as a result of photodegradation of polyethylene terephthalate (PET) bottles used as SODIS reactors. This study assessed genotoxic risk associated with the possible release of genotoxic compounds into water from PET bottles during SODIS, using the Ames fluctuation test. Negative genotoxicity results were obtained for water samples that had been in PET bottles and exposed to normal SODIS conditions (strong natural sunlight) over 6 months. Under SODIS conditions, bottles were exposed to 6 h of sunlight, followed by overnight room temperature storage. They were then emptied and refilled the following day and exposed to sunlight again. Genotoxicity was detected after 2 months in water stored in PET bottles and exposed continuously (without refilling) to sunlight for a period ranging from 1 to 6 months. However, similar genotoxicity results were also observed for the dark control (without refill) samples at the same time-point and in no other samples after that time; therefore it is unlikely that this genotoxicity event is related to solar exposure.

  7. Proposed Use of the NASA Ames Nebula Cloud Computing Platform for Numerical Weather Prediction and the Distribution of High Resolution Satellite Imagery

    Science.gov (United States)

    Limaye, Ashutosh S.; Molthan, Andrew L.; Srikishen, Jayanthi

    2010-01-01

    The development of the Nebula Cloud Computing Platform at NASA Ames Research Center provides an open-source solution for the deployment of scalable computing and storage capabilities relevant to the execution of real-time weather forecasts and the distribution of high resolution satellite data to the operational weather community. Two projects at Marshall Space Flight Center may benefit from use of the Nebula system. The NASA Short-term Prediction Research and Transition (SPoRT) Center facilitates the use of unique NASA satellite data and research capabilities in the operational weather community by providing datasets relevant to numerical weather prediction, and satellite data sets useful in weather analysis. SERVIR provides satellite data products for decision support, emphasizing environmental threats such as wildfires, floods, landslides, and other hazards, with interests in numerical weather prediction in support of disaster response. The Weather Research and Forecast (WRF) model Environmental Modeling System (WRF-EMS) has been configured for Nebula cloud computing use via the creation of a disk image and deployment of repeated instances. Given the available infrastructure within Nebula and the "infrastructure as a service" concept, the system appears well-suited for the rapid deployment of additional forecast models over different domains, in response to real-time research applications or disaster response. Future investigations into Nebula capabilities will focus on the development of a web mapping server and load balancing configuration to support the distribution of high resolution satellite data sets to users within the National Weather Service and international partners of SERVIR.

  8. Mutagenicity and antimutagenicity studies of DRDE-07 and its analogs against sulfur mustard in the in vitro Ames Salmonella/microsome assay.

    Science.gov (United States)

    Vijayan, Vinod; Pathak, Uma; Meshram, Ghansham Pundilikji

    2014-10-01

    Sulfur mustard (bis(2-chloroethyl) sulfide, SM), a chemical warfare agent, is classified as a class I human carcinogen by IARC. No effective antidote against this agent is available. The synthetic aminothiol, amifostine, earlier known as WR-2721, has been extensively used as a chemical radioprotector for normal tissues in cancer radiotherapy and chemotherapy. SM is a radiomimetic agent; this prompted us to evaluate the protective efficacy of amifostine and three of its analogs, DRDE-07 [S-2(2-aminoethylamino) ethyl phenyl sulphide], DRDE-30 [S-2(2-aminoethyl amino) ethyl propyl sulphide] and DRDE-35 [S-2(2-aminoethyl amino) ethyl butyl sulphide], against sulfur mustard-induced mutagenicity in the Ames Salmonella/microsome assay. The antidotes were also evaluated for possible mutagenic activity. DRDE-07 was mutagenic in strain TA104 in the absence of S9; DRDE-30 was mutagenic in strain TA100; amifostine and DRDE-35 did not show mutagenic activity in any of the five tester strains used. SM is mutagenic in strains TA97a and TA102, with or without S9 activation. In the antimutagenicity studies, DRDE-07 and DRDE-35 showed promising antimutagenic activity against SM in the absence of S9, in comparison to amifostine. DRDE-07 and DRDE-35 are promising protective agents against SM-induced mutagenicity. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. Ames Research Center cryogenic mirror testing program - A comparison of the cryogenic performance of metal and glass mirrors with different types of mounts

    Science.gov (United States)

    Miller, Jacob H.; Melugin, Ramsey K.; Augason, Gordon C.; Howard, Steven D.; Pryor, G. Mark

    1989-01-01

    A summary of the cryogenic testing of glass and metal mirrors performed at NASA Ames Research Center (ARC) and two other places is presented. Recent improvements to the ARC Cryogenic Optics Test Facility are described. The purposes of the tests were to determine: (1) how glass mirrors would perform at cryogenic temperatures compared with metal mirrors and (2) how various mirror mounts would affect the cryogenic performance of mirrors. Details of a cryogenic test of a 50 cm 'double arch', fused-silica mirror with a three-point mount and with a radially-compliant, flexured mount are given. Within the accuracy of the measurements, it was determined that the flexured mount did not induce appreciable distortion in the double arch mirror. Results of the cryogenic tests of a number of glass mirrors and two beryllium mirrors are included. The cryogenic distortion of the glass mirrors was found to be less than that for the beryllium mirrors. Within the accuracy of the measurements, no hysteresis was found in the glass mirrors. It was possible to measure hysteresis in one of the beryllium mirrors.

  10. Expression of DNA methyltransferases is influenced by growth hormone in the long-living Ames dwarf mouse in vivo and in vitro.

    Science.gov (United States)

    Armstrong, Vanessa L; Rakoczy, Sharlene; Rojanathammanee, Lalida; Brown-Borg, Holly M

    2014-08-01

    Methyltransferase expression and DNA methylation are linked to aging and age-related disease. We utilized 3-, 12-, and 24-month-old Ames dwarf and their wild-type siblings to examine the genotype and age-related differences in the expression of methyltransferase enzymes related to DNA methylation in the liver, glycine-N-methyltransferase and DNA methyltransferase (DNMT). We found that DNMT proteins and transcripts are differentially expressed in dwarf mice compared with wild-type siblings that can be attributed to age and/or genotype. However, DNMT1 protein expression is drastically reduced compared with wild-type controls at every age. DNMT3a protein levels coincide with differences observed in DNMT activity. Growth hormone appears to modulate expression of DNMT1 and 3a in dwarf liver tissue and primary hepatocytes. Therefore, growth hormone may contribute to age-related processes, DNA methylation, and, ultimately, longevity. © The Author 2013. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  11. Mutagenicity of Tween 80-solvated mild gasification products in the Ames salmonella microsomal assay system. [Quarterly report, October--December 1991

    Energy Technology Data Exchange (ETDEWEB)

    1992-01-13

    The results of the Tween 80-solvated Ames testing of six mild gasification samples indicate significant mutagenic activity only in the composite materials (MG-119 and MG-120), previously suspected from the DMSO-solvated assays, which had shown some variable but ultimately insignificant mutagenic responses. The activity of these samples from the Tween 80-solvated assays was quite low when compared to either the positive controls or the SRC-II HD coal-liquefaction reference material. The class of mutagenic activity expressed by these samples solvated in Tween 80 was that of an indirect-acting, frameshift mutagen(s) since significant activity was found only on tester strain TA98 in the presence of the metabolic activation fraction (S9). Because DMSO and other solvents have been shown to affect the mutagenic activity of certain pure chemicals, the possibility of solvent/mutagen interactions in complex mixtures such as coal-derived liquids exists. Thus, the testing of the genotoxic activity of undefined, chemically complex compounds may require the use of at least two solvent systems to reduce the possibility of artifactual findings. 10 refs., 4 tabs.

  12. Analysis and characterization of heavy residues produced in 129Xe + natSn reactions between 8 and 25 AMeV

    International Nuclear Information System (INIS)

    Moisan, J.

    2008-06-01

    Studies with the INDRA multidetector of the 129 Xe + nat Sn reactions showed the unexpected existence of heavy fragments with a charge as large as Z=70. The charges of Xe and Sn are 54 and 50 respectively. Reactions between nuclei with a charge product greater than 2700 are dominated by deep inelastic collisions. For Xe + Sn the product is exactly 2700. After these observations, 129 Xe + nat Sn reactions at 8, 12, 15, 20 and 25 AMeV have been done. It will then be possible to clarify if the heavy residues are formed by an incomplete fusion, massive transfers occurring in deep inelastic collisions or a very asymmetric fission of a compound system. This work will present experimental results obtained by the analysis of these experiments. We will show that heavy residues are formed with a production cross-section of 10 -2 mb. Angular distributions show that the residues can be produced by an incomplete fusion of the projectile and the target. The study of the products in coincidence with the residues shows that a compound system was formed, followed by a fission producing the residue and a lighter fragment. The comparison with a phenomenological model, HIPSE, confirms that the model is valid at these energies

  13. The role of the Joint Research Centre from the European Commission in the European Structural Integrity Networks AMES, ENIQ and NESC

    International Nuclear Information System (INIS)

    Estorff, U. von; Torronen, K.

    1999-01-01

    Due to the reduction in many countries of the research budget for nuclear safety several European institutions and organisations and the Institute for Advanced Materials (IAM) of the Joint Research Centre (JRC) of the European Commission (EC) have developed co-operative programmes now organised into 'Networks' for mutual benefit. They include utilities, engineering companies, research and development (R and D) laboratories and regulatory bodies. These Networks are all organised and managed in a similar way, i.e. like the successful Programme for the Inspection of Steel Components (PISC). The IAM plays the role of Operating Agent, Reference Laboratory and Network Manager of these Networks: European Network on Ageing Materials Evaluation and Studies (AMES), European Network for Inspection Qualification (ENIQ) and Network for Evaluating Steel Components (NESC), each of them dealing with a specific aspect of fitness for purpose of materials in structural components. This article will describe how the network organisation works, which was the positive experience from the past, why the networks are a tool for integrating fragmented research in Europe and how they fit into the mission of the JRC and therefore follow the EC policy. (orig.)

  14. Control-value theory: using achievement emotions to improve understanding of motivation, learning, and performance in medical education: AMEE Guide No. 64.

    Science.gov (United States)

    Artino, Anthony R; Holmboe, Eric S; Durning, Steven J

    2012-01-01

    In this AMEE Guide, we consider the emergent theoretical and empirical work on human emotion and how this work can inform the theory, research, and practice of medical education. In the Guide, we define emotion, in general, and achievement emotions, more specifically. We describe one of the leading contemporary theories of achievement emotions, control-value theory (Pekrun 2006), and we distinguish between different types of achievement emotions, their proximal antecedents, and their consequences for motivation, learning, and performance. Next, we review the empirical support for control-value theory from non-medical fields and suggest several important implications for educational practice. In this section, we highlight the importance of designing learning environments that foster a high degree of control and value for students. Finally, we end with a discussion of the need for more research on achievement emotions in medical education, and we propose several key research questions we believe will facilitate our understanding of achievement emotions and their impact on important educational outcomes.

  15. Comparison of acoustic data from a 102 mm conic nozzle as measured in the RAE 24-foot wind tunnel and the NASA Ames 40- by 80-foot wind tunnel

    Science.gov (United States)

    Atencio, A., Jr.; Mckie, J.

    1982-01-01

    A cooperative program between the Royal Aircraft Establishment (RAE), England, and the NASA Ames Research Center was initiated to compare acoustic measurements made in the RAE 24-foot wind tunnel and in the Ames 40- by 80-foot wind tunnel. The acoustic measurements were made in both facilities using the same 102 mm conical nozzle supplied by the RAE. The nozzle was tested by each organization using its respective jet test rig. The mounting hardware and nozzle exit conditions were matched as closely as possible. The data from each wind tunnel were independently analyzed by the respective organization. The results from these tests show good agreement. In both facilities, interference with acoustic measurement is evident at angles in the forward quadrant.

  16. Plans for Testing the NREL Unsteady Aerodynamics Experiment 10m Diameter HAWT in the NASA Ames Wind Tunnel: Minutes, Conclusions, and Revised Text Matrix from the 1st Science Panel Meeting

    Energy Technology Data Exchange (ETDEWEB)

    Simms, D.; Schreck, S.; Hand, M.; Fingersh, L.; Cotrell, J.; Pierce, K.; Robinson, M.

    2000-08-28

    Currently, the NREL Unsteady Aerodynamics Experiment (UAE) research turbine is scheduled to enter the NASA Ames 80-ft x 120-ft wind tunnel in early 2000. To prepare for this 3-week test, a Science Panel meeting was convened at the National Wind Technology Center (NWTC) in October 1998. During this meeting, the Science Panel and representatives from the wind energy community provided numerous detailed recommendations regarding test activities and priorities. The Unsteady Aerodynamics team of the NWTC condensed this guidance and drafted a detailed test plan. This test plan represents an attempt to balance diverse recommendations received from the Science Panel meeting, while taking into account multiple constraints imposed by the UAE research turbine, the NASA Ames 80-ft x 120-ft wind tunnel, and other sources. The NREL-NASA Ames wind tunnel tests will primarily be focused on obtaining rotating blade pressure data. NREL has been making these types of measurements since 1987 and has considerable experience in doing so. The purpose of this wind tunnel test is to acquire accurate quantitative aerodynamic and structural measurements, on a wind turbine that is geometrically and dynamically representative of full-scale machines, in an environment free from pronounced inflow anomalies. These data will be exploited to develop and validate enhanced engineering models for designing and analyzing advanced wind energy machines.

  17. A simple model for yield prediction of rice based on vegetation index derived from satellite and AMeDAS data during ripening period

    International Nuclear Information System (INIS)

    Wakiyama, Y.; Inoue, K.; Nakazono, K.

    2003-01-01

    The present study was conducted to show a simple model for rice yield predicting by using a vegetation index (NDVI) derived from satellite and meteorological data. In a field experiment, the relationship between the vegetation index and radiation absorbed by the rice canopy was investigated from transplanting to maturity. Their correlation held. This result revealed that the vegetation index could be used as a measure of absorptance of solar radiation by rice canopy. NDVI multiplied by solar radiation (SR) every day was accumulated (Σ(SR·NDVI)) from the field experiment. Σ(SR·NDVI) was plotted against above ground dry matter. It was obvious that they had a strong relationship. Rice yield largely depends on solar radiation and air temperature during the ripening period. Air temperature affects dry matter production. Relationships between Y SR -1 (Y: rice yield, SR: solar radiation) and mean air temperature were investigated from meteorological data and statistical data on rice yield. There was an optimum air temperature, 21.3°C, for ripening. When it was near 21.3°C in the ripening period, the rice yield was higher. We proposed a simple model for yield prediction of rice based on these results. The model is composed with SR·NDVI and the optimum air temperature. Vegetation index was derived from 3 years, LANDSAT TM data in Toyama, Ishikawa, Fukui and Nagano prefectures at heading. The meteorological data was used from AMeDAS data. The model was described as follows: Y = 0.728 SR·NDVI−2.04(T−21.3) 2 + 282 (r 2 = 0.65, n = 43) where Y is rice yield (kg 10a -1 ), SR is solar radiation (MJ m -2 ) during the ripening period (from 10 days before heading to 30 days after heading), T is mean air temperature (°C) during the ripening period. RMSE was 33.7kg 10a -1 . The model revealed good precision. (author)

  18. Full-scale S-76 rotor performance and loads at low speeds in the NASA Ames 80- by 120-Foot Wind Tunnel. Vol. 1

    Science.gov (United States)

    Shinoda, Patrick M.

    1996-01-01

    A full-scale helicopter rotor test was conducted in the NASA Ames 80- by 120-Foot Wind Tunnel with a four-bladed S-76 rotor system. Rotor performance and loads data were obtained over a wide range of rotor shaft angles-of-attack and thrust conditions at tunnel speeds ranging from 0 to 100 kt. The primary objectives of this test were (1) to acquire forward flight rotor performance and loads data for comparison with analytical results; (2) to acquire S-76 forward flight rotor performance data in the 80- by 120-Foot Wind Tunnel to compare with existing full-scale 40- by 80-Foot Wind Tunnel test data that were acquired in 1977; (3) to evaluate the acoustic capability of the 80- by 120- Foot Wind Tunnel for acquiring blade vortex interaction (BVI) noise in the low speed range and compare BVI noise with in-flight test data; and (4) to evaluate the capability of the 80- by 120-Foot Wind Tunnel test section as a hover facility. The secondary objectives were (1) to evaluate rotor inflow and wake effects (variations in tunnel speed, shaft angle, and thrust condition) on wind tunnel test section wall and floor pressures; (2) to establish the criteria for the definition of flow breakdown (condition where wall corrections are no longer valid) for this size rotor and wind tunnel cross-sectional area; and (3) to evaluate the wide-field shadowgraph technique for visualizing full-scale rotor wakes. This data base of rotor performance and loads can be used for analytical and experimental comparison studies for full-scale, four-bladed, fully articulated rotor systems. Rotor performance and structural loads data are presented in this report.

  19. Inhalational anthrax (Ames aerosol in naive and vaccinated New Zealand rabbits: characterizing the spread of bacteria from lung deposition to bacteremia.

    Directory of Open Access Journals (Sweden)

    Bradford eGutting

    2012-06-01

    Full Text Available There is a need to better understand inhalational anthrax in relevant animal models. This understanding could aid risk assessment, help define therapeutic windows, and provide a better understanding of disease. The aim here was to characterize and quantify bacterial deposition and dissemination in rabbits following exposure to single high aerosol dose (>100LD50 of Bacillus anthracis (Ames spores immediately following exposure through 36 hours. The primary goal of collecting the data was to support investigators in developing computational models of inhalational anthrax disease. Rabbits were vaccinated prior to exposure with the human vaccine (Anthrax Vaccine Adsorbed, AVA or were sham-vaccinated, and were then exposed in pairs (1 sham and 1 AVA so disease kinetics could be characterized in equally-dosed hosts where one group is fully protected and is able to clear the infection (AVA-vaccinated, while the other is susceptible to disease, in which case the bacteria are able to escape containment and replicate uncontrolled (sham-vaccinated rabbits. Between 4-5% of the presented aerosol dose was retained in the lung of sham- and AVA-vaccinated rabbits as measured by dilution plate analysis of homogenized lung tissue or bronchoalveolar lavage (BAL fluid. After 6 and 36 hours, >80% and >96%, respectively, of the deposited spores were no longer detected in BAL, with no detectable difference between sham- or AVA-vaccinated rabbits. Thereafter, differences between the two groups became noticeable. In sham-vaccinated rabbits the bacteria were detected in the tracheobronchial lymph nodes (TBLN 12 hours post exposure and in the circulation at 24 hours, a time point which was also associated with dramatic increases in vegetative CFU in the lung tissue of some animals. In all sham-vaccinated rabbits, bacteria increased in both TBLN and blood through 36 hours at which point in time some rabbits succumbed to disease. In contrast, AVA-vaccinated rabbits showed

  20. The Mars Dust Cycle: Investigating the Effects of Radiatively Active Water Ice Clouds on Surface Stresses and Dust Lifting Potential with the NASA Ames Mars General Circulation Model

    Science.gov (United States)

    Kahre, Melinda A.; Hollingsworth, Jeffery

    2012-01-01

    The dust cycle is a critically important component of Mars' current climate system. Dust is present in the atmosphere of Mars year-round but the dust loading varies with season in a generally repeatable manner. Dust has a significant influence on the thermal structure of the atmosphere and thus greatly affects atmospheric circulation. The dust cycle is the most difficult of the three climate cycles (CO2, water, and dust) to model realistically with general circulation models. Until recently, numerical modeling investigations of the dust cycle have typically not included the effects of couplings to the water cycle through cloud formation. In the Martian atmosphere, dust particles likely provide the seed nuclei for heterogeneous nucleation of water ice clouds. As ice coats atmospheric dust grains, the newly formed cloud particles exhibit different physical and radiative characteristics. Thus, the coupling between the dust and water cycles likely affects the distributions of dust, water vapor and water ice, and thus atmospheric heating and cooling and the resulting circulations. We use the NASA Ames Mars GCM to investigate the effects of radiatively active water ice clouds on surface stress and the potential for dust lifting. The model includes a state-of-the-art water ice cloud microphysics package and a radiative transfer scheme that accounts for the radiative effects of CO2 gas, dust, and water ice clouds. We focus on simulations that are radiatively forced by a prescribed dust map, and we compare simulations that do and do not include radiatively active clouds. Preliminary results suggest that the magnitude and spatial patterns of surface stress (and thus dust lifting potential) are substantial influenced by the radiative effects of water ice clouds.

  1. Final work plan: Expedited Site Characterization of the IES Industries, Inc., Site at Marshalltown, Iowa. Ames Expedited Site Characterization Project, Version 1.0

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-04

    The overall goal of the Ames Laboratory Expedited Site Characterization (ESC) project is to evaluate and promote both innovative and state-of-the-practice site characterization and/or monitoring technologies. This will be accomplished by fielding both types of technologies together in the context of an expedited site characterization. The first site will be at a former manufactured gas plant (FMGP) in Marshalltown, Iowa. The project will field three areas of technology: geophysical, analytical, and data fusion. Geophysical technologies are designed to understand the subsurface geology to help predict fate and transport of the target contaminants. Analytical technologies/methods are designed to detect and quantify the target contaminants. Data fusion technology consists of software systems designed to rapidly integrate or fuse all site information into a conceptual site model that then becomes the decision making tool for the site team to plan subsequent sampling activity. Not all of the contaminants present can be located at the action level. Polynuclear aromatic hydrocarbons (PAHs) are the signature organics associated with the coal tar activities that took place at the site. As a result, PAHs were selected as the target compounds. Screening analytical instruments and nonintrusive geophysical techniques will be fielded to qualitatively map the spatial contaminant distribution. Soil gas surveys, immunoassay testing (IMA), innovative optical techniques, and passive organic sorbent sensors will be deployed along with the geophysical methods. Gas chromatography/mass spectrometry (GC/MS) instruments and a cone penetrometer system equipped with a laser-induced fluorescence (LIF) probe will quantitatively map the action level edges of the PAH plume(s). Samples will be taken both by the cone penetrometer test system (CPT) and the Geoprobe {reg_sign} sampler system.

  2. piplartine by the Ames test

    African Journals Online (AJOL)

    Administrator

    2011-06-15

    Jun 15, 2011 ... azide (1.25 µg per plate) for TA100, 4 nitro-ophenylenediamine (10. µg per plate) and 2-aminoanthracene (1.25 µg per plate) for TA98 and TA97a, and mitomycin C (0.25 µg per plate) and 2- aminofluorene (5 µg per plate) for TA102. Dimethyl sulfoxide served as the negative (solvent) control (Bernstein et ...

  3. Biological Visualization, Imaging and Simulation(Bio-VIS) at NASA Ames Research Center: Developing New Software and Technology for Astronaut Training and Biology Research in Space

    Science.gov (United States)

    Smith, Jeffrey

    2003-01-01

    The Bio- Visualization, Imaging and Simulation (BioVIS) Technology Center at NASA's Ames Research Center is dedicated to developing and applying advanced visualization, computation and simulation technologies to support NASA Space Life Sciences research and the objectives of the Fundamental Biology Program. Research ranges from high resolution 3D cell imaging and structure analysis, virtual environment simulation of fine sensory-motor tasks, computational neuroscience and biophysics to biomedical/clinical applications. Computer simulation research focuses on the development of advanced computational tools for astronaut training and education. Virtual Reality (VR) and Virtual Environment (VE) simulation systems have become important training tools in many fields from flight simulation to, more recently, surgical simulation. The type and quality of training provided by these computer-based tools ranges widely, but the value of real-time VE computer simulation as a method of preparing individuals for real-world tasks is well established. Astronauts routinely use VE systems for various training tasks, including Space Shuttle landings, robot arm manipulations and extravehicular activities (space walks). Currently, there are no VE systems to train astronauts for basic and applied research experiments which are an important part of many missions. The Virtual Glovebox (VGX) is a prototype VE system for real-time physically-based simulation of the Life Sciences Glovebox where astronauts will perform many complex tasks supporting research experiments aboard the International Space Station. The VGX consists of a physical display system utilizing duel LCD projectors and circular polarization to produce a desktop-sized 3D virtual workspace. Physically-based modeling tools (Arachi Inc.) provide real-time collision detection, rigid body dynamics, physical properties and force-based controls for objects. The human-computer interface consists of two magnetic tracking devices

  4. Participación política y violencia de género en América Latina

    Directory of Open Access Journals (Sweden)

    Laura Albaine

    2014-07-01

    Full Text Available Este artículo reflexiona a través del análisis de fac- tores socioculturales e institucionales sobre uno de los obstáculos más graves que condicionan la participación política de las mujeres en América Latina: El acoso y vio- lencia política en razón de género. Esta problemática es una nueva expresión que ha adoptado la violencia de gé- nero en la arena política que restringe el ejercicio de los derechos políticos de las mujeres y el derecho a vivir una vida libre de violencia. El acoso y violencia política se manifiesta más allá de los avances normativos logrados en la región orientados a generar condiciones de igualdad en términos de género en la participación política. En consecuencia, a las nor- mas que promueven el acceso de las mujeres a cargos de decisión, tales como cuotas o paridad, deben sumársele cuerpos legales que garanticen, además de sus derechos políticos, su seguridad y sus derechos humanos. AbstractThis paper focuses on a reflection and analysis of socio-cultural and institutional factors that affect wom- en’s political participation Latin America, such as gen- der-based harassment and violence. This problem is a new expression that has adopted gender-based violence in political arena, restricting not only the exercise of women’s political rights but also their right to live a life free of violence. Despite Latin American countries have enacted laws to create conditions in terms of gender equality in polit- ical participation, political harassment and violence still occurs. However, these policy actions are not enough to ensure women’s access to decision-making positions, such as quotas or parity; it must also be legal bodies to ensure, in addition to their political rights, their personal safety and human rights. 

  5. UVA activation of N-dialkylnitrosamines releasing nitric oxide, producing strand breaks as well as oxidative damages in DNA, and inducing mutations in the Ames test.

    Science.gov (United States)

    Arimoto-Kobayashi, Sakae; Sano, Kayoko; Machida, Masaki; Kaji, Keiko; Yakushi, Keiko

    2010-09-10

    We investigated the photo-mutagenicity and photo-genotoxicity of N-dialkylnitrosamines and its mechanisms of UVA activation. With simultaneous irradiation of UVA, photo-mutagenicity of seven N-dialkylnitrosamines was observed in Ames bacteria (Salmonella typhimurium TA1535) in the absence of metabolic activation. Mutagenicity of pre-irradiated N-dialkylnitrosamines was also observed with S. typhimurium hisG46, TA100, TA102 and YG7108 in the absence of metabolic activation. UVA-mediated mutation with N-nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA) decreased by adding either the NO or OH radical scavenger. When superhelical DNA was irradiated with N-dialkylnitrosamines, nicked circular DNA appeared. Ten N-dialkylnitrosamines examined produced strand breaks in the treated DNA in the presence of UVA. The level of single-strand breaks in phiX174 DNA mediated by N-nitrosomorpholine (NMOR) and UVA decreased by adding either a radical scavenger or superoxide dismutase. When calf thymus DNA was treated with N-dialkylnitrosamines (NDMA, NDEA, NMOR, N-nitrosopyrrolidine (NPYR) and N-nitrosopiperidine (NPIP)) and UVA, the ratio of 8-oxodG/dG in the DNA increased. Action spectra were obtained to determine if nitrosamine acts as a sensitizer of UVA. Both mutation frequency and NO formation were highest at the absorption maximum of nitrosamines, approximately 340 nm. The plots of NO formation and mutation frequency align with the absorption curve of NPYR, NMOR and NDMA. A significant linear correlation between the optical density of N-dialkynitrosamines at 340 nm and NO formation in each irradiated solution was revealed by ANOVA. We would like to propose the hypothesis that the N-nitroso moiety of N-dialkylnitrosamines absorbs UVA photons, UVA-photolysis of N-dialkylnitrosamines brings release of nitric oxide, and subsequent production of alkyl radical cations and active oxygen species follow as secondary events, which cause DNA strand breaks, oxidative and

  6. UVA activation of N-dialkylnitrosamines releasing nitric oxide, producing strand breaks as well as oxidative damages in DNA, and inducing mutations in the Ames test

    Energy Technology Data Exchange (ETDEWEB)

    Arimoto-Kobayashi, Sakae, E-mail: arimoto@cc.okayama-u.ac.jp [Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 1-1-1 Tsushima, Okayama 700-8530 (Japan); Sano, Kayoko; Machida, Masaki; Kaji, Keiko; Yakushi, Keiko [Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 1-1-1 Tsushima, Okayama 700-8530 (Japan)

    2010-09-10

    We investigated the photo-mutagenicity and photo-genotoxicity of N-dialkylnitrosamines and its mechanisms of UVA activation. With simultaneous irradiation of UVA, photo-mutagenicity of seven N-dialkylnitrosamines was observed in Ames bacteria (Salmonella typhimurium TA1535) in the absence of metabolic activation. Mutagenicity of pre-irradiated N-dialkylnitrosamines was also observed with S. typhimurium hisG46, TA100, TA102 and YG7108 in the absence of metabolic activation. UVA-mediated mutation with N-nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA) decreased by adding either the NO or OH radical scavenger. When superhelical DNA was irradiated with N-dialkylnitrosamines, nicked circular DNA appeared. Ten N-dialkylnitrosamines examined produced strand breaks in the treated DNA in the presence of UVA. The level of single-strand breaks in {phi}X174 DNA mediated by N-nitrosomorpholine (NMOR) and UVA decreased by adding either a radical scavenger or superoxide dismutase. When calf thymus DNA was treated with N-dialkylnitrosamines (NDMA, NDEA, NMOR, N-nitrosopyrrolidine (NPYR) and N-nitrosopiperidine (NPIP)) and UVA, the ratio of 8-oxodG/dG in the DNA increased. Action spectra were obtained to determine if nitrosamine acts as a sensitizer of UVA. Both mutation frequency and NO formation were highest at the absorption maximum of nitrosamines, approximately 340 nm. The plots of NO formation and mutation frequency align with the absorption curve of NPYR, NMOR and NDMA. A significant linear correlation between the optical density of N-dialkynitrosamines at 340 nm and NO formation in each irradiated solution was revealed by ANOVA. We would like to propose the hypothesis that the N-nitroso moiety of N-dialkylnitrosamines absorbs UVA photons, UVA-photolysis of N-dialkylnitrosamines brings release of nitric oxide, and subsequent production of alkyl radical cations and active oxygen species follow as secondary events, which cause DNA strand breaks, oxidative and

  7. Specific interactions of growth hormone (GH) with GH-receptors and GH-binding proteins in vivo in genetically GH-deficient Ames dwarf mice.

    Science.gov (United States)

    Turyn, D; Dominici, F P; Sotelo, A I; Bartke, A

    1998-10-01

    The fate of exogenous radiolabeled growth hormone (125I-hGH) was studied in Ames dwarf mice, which do not express growth hormone (GH) or prolactin (PRL) genes. Labeled GH was injected in low amounts that did not exceed the normal physiological GH concentration in mice. Binding of most of the injected 125I-hGH by the GH-binding proteins (GHBPs) present in plasma represents the first step in the handling of this material in vivo. The decay curve followed a two-compartment model and gave the equation: Conc = 2.807e-0067t + 15301e-0.0647t (coefficient of determination 0.9986+/-0.0019), while in normal mice, GH decay followed a three-compartment model as we have previously reported. The fast compartment with t1/2 of 1-2 min was virtually absent in dwarf mice, and chromatographic studies revealed the disappearance of free GH in these mice. We also present evidence of the labeled GH-forming complexes, presumably with GHBPs under in vivo conditions. The second step of processing labeled GH in vivo is the uptake by the liver, which was slower in dwarf than in normal mice (30-45 vs 15 min). Moreover, a lower GH uptake was found in dwarf than in normal mice (UB ratio of 1.75+/-0.29 [30 min] vs L/B ratio of 3.68+/-0.33 [15 min], respectively) due to lower concentration of free GH in plasma and to the reduced number of GH-receptors (GHRs). The radioactive material present in the liver was compatible with 125I-hGH-GHR complexes with Stokes radius of 59A. In summary, we provide evidence that plasma of dwarf mice contains proteins capable of binding GH in vivo and probably representing GHBPs not complexed with GH. The presence of these proteins modified the pharmacokinetics of 125I-hGH in plasma and its subsequent uptake by the liver. The presence of these binding proteins in the absence of endogenous GH suggests that a fraction of total GHBPs (one class?) is independent of GH concentration.

  8. Measurement of isotopic cross sections of the fission fragments produced in 500 AMeV {sup 208}Pb + p reaction; Etude de la production des fragments de fission issus de la reaction {sup 208}Pb + p a 500 AMeV

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez-Dominguez, B

    2003-03-01

    The aim of this work is the study of the fission fragments produced in the spallation reaction {sup 208}Pb + p at 500 AMeV. The fission fragments from Z=23 up to Z=59 have been detected and identified by using the inverse kinematics technique with the high-resolution spectrometer FRS. The production cross sections and the recoil velocities of 430 nuclei have been measured. The measured data have been compared with previous data. The isotopic distributions show a high precision. However, the absolute value of the fission cross section is higher than expected. From the experimental data the characteristics of the average fissioning system have been reconstructed (Z{sub fis}, A{sub fis}, E*{sub fis}). In addition, the number of post-fission neutrons emitted from the fission fragments, v{sub post}, has been determined by using a new method. The experimental data have been compared to the two-steps models describing the spallation reaction. The impact of the model parameters on the observables has been analysed and the reasons Leading to the observed differences between the codes are also presented. This analyse shows a good agreement with the INCL4+ABLA code. (author)

  9. Investigations of the 0.020-scale 88-OTS Integrated Space Shuttle Vehicle Jet-Plume Model in the NASA/Ames Research Center 11 by11-Foot Unitary Plan Wind Tunnel (IA80). Volume 1

    Science.gov (United States)

    Nichols, M. E.

    1976-01-01

    The results are documented of jet plume effects wind tunnel test of the 0.020-scale 88-OTS launch configuration space shuttle vehicle model in the 11 x 11 foot leg of the NASA/Ames Research Center Unitary Plan Wind Tunnel. This test involved cold gas main propulsion system (MPS) and solid rocket motor (SRB) plume simulations at Mach numbers from 0.6 to 1.4. Integrated vehicle surface pressure distributions, elevon and rudder hinge moments, and wing and vertical tail root bending and torsional moments due to MPS and SRB plume interactions were determined. Nozzle power conditions were controlled per pretest nozzle calibrations. Model angle of attack was varied from -4 deg to +4 deg; model angle of sideslip was varied from -4 deg to +4 deg. Reynolds number was varied for certain test conditions and configurations, with the nominal freestream total pressure being 14.69 psia. Plotted force and pressure data are presented.

  10. Caracterización molecular de Colletotrichum gloeosporioides aislado de plantas de ñame de la Costa Atlántica Colombiana utilizando la técnica “DNA Amplification Fingerprinting (DAF”

    Directory of Open Access Journals (Sweden)

    Natalia Giraldo Marroquín

    2016-01-01

    Full Text Available La antracnosis en ñame, causada por el hongo Colletotrichum gloeosporioides, es una enfermedad relevante que posee el potencial de destruir el 100% de la cosecha, convirtiéndose en la principal limitante fitosanitaria para el rendimiento del cultivo en el país. Esta es una situación preocupante considerando que aproximadamente 35.000 familias de pequeños y medianos agricultores de la Costa Atlántica Colombiana subsisten de este cultivo; es por esto que el objetivo de este trabajo fue caracterizar molecularmente 42 aislamientos del hongo procedentes de plantas de ñame con síntomas de la enfermedad, utilizando la técnica molecular “DNA Amplification Fingerprinting (DAF”, caracterizada por su resolución en la determinación de la variabilidad genética de diferentes organismos. Para la determinación de polimorfismos, se amplificaron 16 marcadores DAF implementando iniciadores tipo decámero, los cuales fueron visualizados por electroforesis en microchip con el equipo MCE-202 MultiNA. Se evaluó la reproducibilidad de la técnica DAF. La amplificación arrojó 391 bandas inequívocamente polimórficas en todas las muestras, el coeficiente de Dice identificó cinco grupos con 0.30% de similaridad y el índice de diversidad genética fue de 0.28; datos que reflejan un alto grado de variabilidad en la colección estudiada de C. gloeosporioides. Ésta puede deberse, al intercambio de germoplasma, a su condición heterotálica, a las mutaciones y al alto potencial de dispersión de las conidias que le permiten mantener la viabilidad bajo condiciones adversas. Por último, se encontró que DAF es una técnica reproducible, confirmando que es una metodología fiable para la caracterización molecular de hongos.

  11. An automated, open-source (NASA Ames Stereo Pipeline) workflow for mass production of high-resolution DEMs from commercial stereo satellite imagery: Application to mountain glacies in the contiguous US

    Science.gov (United States)

    Shean, D. E.; Arendt, A. A.; Whorton, E.; Riedel, J. L.; O'Neel, S.; Fountain, A. G.; Joughin, I. R.

    2016-12-01

    We adapted the open source NASA Ames Stereo Pipeline (ASP) to generate digital elevation models (DEMs) and orthoimages from very-high-resolution (VHR) commercial imagery of the Earth. These modifications include support for rigorous and rational polynomial coefficient (RPC) sensor models, sensor geometry correction, bundle adjustment, point cloud co-registration, and significant improvements to the ASP code base. We outline an automated processing workflow for 0.5 m GSD DigitalGlobe WorldView-1/2/3 and GeoEye-1 along-track and cross-track stereo image data. Output DEM products are posted at 2, 8, and 32 m with direct geolocation accuracy of scale batch processing in a high-performance computing environment. We have leveraged these resources to produce dense time series and regional mosaics for the Earth's ice sheets. We are now processing and analyzing all available 2008-2016 commercial stereo DEMs over glaciers and perennial snowfields in the contiguous US. We are using these records to study long-term, interannual, and seasonal volume change and glacier mass balance. This analysis will provide a new assessment of regional climate change, and will offer basin-scale analyses of snowpack evolution and snow/ice melt runoff for water resource applications.

  12. Space Shuttle AFRSI OMS pod environment test using model 81-0 test fixture in the Ames Research Center 9x7-foot supersonic wind tunnel (OS-314A/B/C)

    Science.gov (United States)

    Collette, J. G. R.

    1984-01-01

    A test was conducted in the NASA/Ames Research Center 9x7-foot Supersonic Wind Tunnel to help resolve an anomaly that developed during the STS-6 orbiter flight wherein sections of the Advanced Flexible Reusable Surface Insulation (AFRSI) covering the OMS pods suffered some damage. A one-third scale two-dimensional shell structure model of an OMS pod cross-section was employed to support the test articles. These consisted of 15 AFRSI blanket panels form-fitted over the shell structures for exposure to simulated flight conditions. Of six baseline blankets, two were treated with special surface coatings. Two other panels were configured with AFRSI sections removed from the OV099 orbiter vehicle after the STS-6 flight. Seven additional specimens incorporated alternative designs and repairs. Following a series of surface pressure calibration runs, the specimens were exposed to simulated ascent and entry dynamic pressure profiles. Entry conditions included the use of a vortex generator to evaluate the effect of shed vortices on the AFRSI located in the area of concern.

  13. Biomonitoring of the genotoxic potential of aqueous extracts of soils and bottom ash resulting from municipal solid waste incineration, using the comet and micronucleus tests on amphibian (Xenopus laevis) larvae and bacterial assays (Mutatox and Ames tests).

    Science.gov (United States)

    Mouchet, F; Gauthier, L; Mailhes, C; Jourdain, M J; Ferrier, V; Triffault, G; Devaux, A

    2006-02-15

    The management of contaminated soils and wastes is a matter of considerable human concern. The present study evaluates the genotoxic potential of aqueous extracts of two soils (leachates) and of bottom ash resulting from municipal solid waste incineration (MSWIBA percolate), using amphibian larvae (Xenopus laevis). Soil A was contaminated by residues of solvents and metals and Soil B by polycyclic aromatic hydrocarbons and metals. MSWIBA was predominantly contaminated by metals. Two genotoxic endpoints were analysed in circulating erythrocytes taken from larvae: clastogenic and/or aneugenic effects (micronucleus induction) after 12 days of exposure and DNA-strand-breaking potency (comet assay) after 1 and 12 days of exposure. In addition, in vitro bacterial assays (Mutatox and Ames tests) were carried out and the results were compared with those of the amphibian test. Physicochemical analyses were also taken into account. Results obtained with the amphibians established the genotoxicity of the aqueous extracts and the comet assay revealed that they were genotoxic from the first day of exposure. The latter test could thus be considered as a genotoxicity-screening tool. Although genotoxicity persisted after 12 days' exposure, DNA damage decreased overall between days 1 and 12 in the MSWIBA percolate, in contrast to the soil leachates. Bacterial tests detected genotoxicity only for the leachate of soil A (Mutatox). The results confirm the ecotoxicological relevance of the amphibian model and underscore the importance of bioassays, as a complement to physico-chemical data, for risk evaluation.

  14. Nuga selga : endine lähikondne teeb maha president Bushi valitsusaja / Kaivo Kopli

    Index Scriptorium Estoniae

    Kopli, Kaivo

    2008-01-01

    Endine Valge Maja pressiesindaja Scott McClellan kirjutas kritiseeriva raamatu "What Happened" president George W. Bushist ja tema kaastöötajatest. Vt. samas: "Me oleme segaduses. See pole Scott, keda me tundsime"; Väljavõtteid Scott McClellani raamatust

  15. Eesti Energia kontrolliüksus teeb elektrivaraste elu kibedaks / Signe Kalberg

    Index Scriptorium Estoniae

    Kalberg, Signe, 1959-

    2006-01-01

    2005. aastal alustas tööd nn elektripolitsei, kes tegeleb kahtlustäratavate objektide kontrolliga. 2005. aasta aprillist 2006. aasta jaanuarini tuvastati 1770 elektrienergia varguse juhtu. Lisa: Elektrivargused; Suur kõikumine jääb silma

  16. eMapps teeb tehnoloogiaga sõbraks noored ja vanad / Ave Lauringson

    Index Scriptorium Estoniae

    Lauringson, Ave

    2007-01-01

    Tallinna 32. Keskkooli 3. ja 4. klassi õpilaste ning eTwinning rahvusvahelisel koolitusel osalevate õpetajate õppemängust Rocca al Mare Vabaõhumuuseumis Euroopa Komisjoni haridusprojekti eMapps.com raames

  17. Jarosław Kaczyński teeb õigust ja õiglust / Andrei Hvostov

    Index Scriptorium Estoniae

    Hvostov, Andrei, 1963-

    2010-01-01

    Poola saatusele võib väga oluliseks muutuda Poola hukkunud presidendi kaksikvenna Jarosław Kaczyński edasine käitumine. Venemaal loodetakse praegu Poola presidendi kohuseid täitva Bronisław Komorowski võitu eelseisvatel Poola presidendivalimistel

  18. Näitleja teeb vahekokkuvõtte ehk Kuidas lavastatakse aega / Katrin Ruus

    Index Scriptorium Estoniae

    Ruus, Katrin

    2006-01-01

    Von Krahli Teatri kolmest lavastusest: "Erki ja Tiina" (lavastaja Mart Kangro, tantsivad Erki Laur ja Tiina Tauraite), "Faust" (J. W. Goethe ainetel tekst ja lavastus Taavi Eelmaa, muusika ja laulud Chalice, osades Jarek Kasar ja Rein Pakk), "Hamletid" (William Shakespeare'i ainetel kontseptsiooni, lavastuse, koreograafia, kujunduse, valguse autor Sasha Pepeljajev, video- ja helikunstnik Taavet Jansen. Esitaja Juhan Ulfsak)

  19. Gazprom teeb reformi: Ukrainal on aeg gaasipliidid nurka visata / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2009-01-01

    Autor leiab, et Ukraina pole 2006. a. kriisist midagi õppinud, maagaasi tarbimine on veelgi suurenenud. Gaasihinna tõusu korral hakatakse Ukrainas ilmselt üha enam loobuma gaasipliitidest ja -boileritest ning niimoodi kaotaks Gazprom ühe oma suurema turu. Gazprom üritab kõrgemat gaasihinda saavutada ka SRÜ maades. Diagrammid

  20. Eesti Miss teeb videofilmi / Evelyn Mikomägi ; interv. Valdo Jahilo

    Index Scriptorium Estoniae

    Mikomägi, Evelyn

    2001-01-01

    Eesti Miss Estonia 2000 Evelyn Mikomägi tegi koos sõbra, Sven-Olof Svenne Englundiga dokfilmi Küprosel peetud maailma suurimast iludusvõistlusest Miss Universe 2000. Neile kuulub ühisfirma "Living Frames" Rootsis, mille peategevus on suunatud 16mm ja 35mm filmide tootmisele

  1. Uute doktorite nappus teeb ülikoolile muret / Jüri Saar

    Index Scriptorium Estoniae

    Saar, Jüri, 1973-

    2004-01-01

    Ülevaade Tartu Ülikooli doktoriõpingute kohta tehtud analüüsi tulemustest. Probleemina torkab silma doktorikraadini jõudnute madal protsent doktoriõpinguid alustanutest. Ka tellib riik doktorante ebapiisavalt, lõpetanute hulk ei kata isegi kõrgkoolide vajadusi

  2. Koolitark teeb õpetaja töö hoopis lihtsamaks / Eve Kruuse

    Index Scriptorium Estoniae

    Kruuse, Eve, 1959-

    2009-01-01

    Tallinna 32. keskkoolis kaheaastase testperioodi läbinud õpetajate tööd kergendavast veebikeskkonnast nimega Koolitark. Tarkvara sündis õppealajuhataja Ants Rebase ja 32. keskkooli IT-tugiisiku Marko Sohardi koostöös

  3. Benjamin Verdery teeb klassikast laheda show / Mari Hiiemäe

    Index Scriptorium Estoniae

    Hiiemäe, Mari

    2008-01-01

    Seitsmendate Eesti kitarrimuusikapäevade Fiesta de la Guitarra 2008 ja peaesinejast, USAst pärit kitarristist Benjamin Verdery'st (esineb 8. nov. Tallinnas Mederi saalis ja 9. nov. Vanemuise kammersaalis), festivalist

  4. ERP ehk tarkvara, mis teab ja teeb kõike / Kadri Põdra, Randel Uibo, Heiti Kender

    Index Scriptorium Estoniae

    Põdra, Kadri

    2006-01-01

    ERP (Enterprise Resource Planning) on majandustarkvara, mis võimaldab hallata ühtses süsteemis ettevõtte kõiki majandusandmeid ja äriprotsesse. Uuringufirma Faktum & Ariko poolt 2005. a. detsembris tehtud uuringust ERP-süsteemide kasutamise kohta Eesti suurettevõtetes. Lisatud statistilised diagrammid

  5. I samba kasv teeb II samba kasvule ära / Raivo Sormunen

    Index Scriptorium Estoniae

    Sormunen, Raivo, 1976-

    2006-01-01

    Ilmunud ka: Delovõje Vedomosti 5. apr. lk. 30. Eesti tugev majanduskasv ning maksude hea laekumine on viinud olukorrani, kus esimese samba pensionid kasvavad kiiremini kui investeeringud teise sambasse. Diagrammid. Vt. samas: Fondid liiguvad omasoodu

  6. Reklaamitööstus teeb naise kehast universaalse märgi / Veljo Sepp

    Index Scriptorium Estoniae

    Sepp, Veljo

    2005-01-01

    Piret Räni ühiskonnakriitiline näitus "Hello friend, are you impotent?" Eesti Kunstiakadeemia galeriis. Näha digitrükis kollaazhipannood ning fotouurimus naise keha kasutamisest ruumis ja meedias

  7. Vaata, mis Tallinn inimesega teeb! / Madis Jürgen, Jan Uuspõld

    Index Scriptorium Estoniae

    Jürgen, Madis, 1962-

    2007-01-01

    Jan Uuspõld, Madis Jürgen ja Rain Tolk vaatavad filmistuudio montaazhitoas Rain Tolgi-Andres Maimiku äsjavalminud komöödiat "Jan Uuspõld läheb Tartusse" ja kommenteerivad. (OÜ "Kuukulgur Film", 2007)

  8. Loeb või ei loe : mis teeb ITst tarbekauba? / Enrique Dans

    Index Scriptorium Estoniae

    Dans, Enrique

    2004-01-01

    Vastukajad ajakirja Think! 2003. aasta 2. numbris avaldatud Nicholas Carr'i artiklile "IT ei loe". Autor ei nõustu enamike N. Carr'i järeldustega IT-st kui tarbekaubast ja esitab IT innovatsiooni kolmetasemelise mudeli

  9. Korruptsioonihõng : politsei teeb Narvas suurpuhastust / Tanel Mazur, Kärt Anvelt

    Index Scriptorium Estoniae

    Mazur, Tanel, 1971-

    2008-01-01

    Seoses 2007. aasta augustis alustatud kriminaalasjaga otsis kaitsepolitsei Narvas läbi ka abilinnapea Sofia Homjakova kabineti, kriminaalasja raames pole kellelegi kahtlustusi esitatud. Vt. samas: Ärimehed: Ida-Virumaal maksab iga liigutus

  10. "Mida mina ei julge, teeb Homer filmis ära!" / Katrin Pauts

    Index Scriptorium Estoniae

    Pauts, Katrin, 1977-

    2007-01-01

    21. juulil on joonisfilmi "Simpsonite film" ("The Simpsons Movie") maailmaesilinastus. Seriaali suur fänn, saatejuht Kristjan Jõekalda sellest, miks talle Simpsonid meeldivad. Lisaks "Marge'i juuksed on inspireeritud Frankenteini pruudist"

  11. Poliitkabaree "Mental Finland" torgib kõike, mis valu teeb / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2009-01-01

    19. veebr. Brüsselis Flaami Kuninglikus Teatris esietendunud Kristian Smedsi lavastusest "Mental Finland", milles osalevad üheteistkümne rahvuse esindajad , sealhulgas eesti näitlejad Juhan Ulfsak ja Eva Klemets

  12. Hüppeline aktsiisitõus teeb ruumi salaviinale / Hindrek Riikoja

    Index Scriptorium Estoniae

    Riikoja, Hindrek

    2007-01-01

    Ilmunud ka: Postimees : na russkom jazõke 15. mai lk. 5. Konjunktuuriinstituudi uuringu järgi tarbis keskmine eestimaalane 2006. aastal 11, 4 liitrit 100 %-list alkoholi. Valitsuse plaanist tõsta alkoholiaktsiisi. Lisa: Suurem palk lubab rohkem juua

  13. Victoria suudlus teeb maapoisist printsi, kuid mitte tulevase kuninga / Kaivo Kopli

    Index Scriptorium Estoniae

    Kopli, Kaivo

    2010-01-01

    Printsess Victoria tulevasest abikaasast Daniel Westlingist, printsess Madelaine'i kihluse lõpetamisest, Bernadotte'ide dünastia asutajast Jean Bernadotte'ist. Monarhia toetajate vähenemisest Rootsis. Printsess Victoria ja Daniel Westlingi pulmatseremooniast 19. juunil

  14. Samara miilits teeb EL-i ja Vene tippkohtumise eel sooja / Igor Taro

    Index Scriptorium Estoniae

    Taro, Igor

    2007-01-01

    Ilmunud ka: Postimees : na russkom jazõke, 16. mai 2007, lk. 7. Enne EL-i ja venemaa tippkohtumist vahistati Samaras mitu opositsiooniaktivisti, valitsuse suhtes kriitilisi meediaväljaandeid külastasid tarkvara- ja maksukontrollid. Lisa: Samara valmistub külaliste vastuvõtuks

  15. Start-up´ide kasvataja: kapitalisüst teeb laisaks / Ilmar Kahro

    Index Scriptorium Estoniae

    Kahro, Ilmar

    2011-01-01

    Soomlase Kristo Ovaska hinnangul on nii Soomes kui ka mujal Euroopas suund, et avalikku raha antakse start-up´idele liiga varajases staadiumis liiga lihtsalt, see on ettevõtjatele pigem karuteene. Uute innovaatilisete ettevõtete loomises jääb Euroopa Aasiale ja Põhja-Ameerikale alla

  16. Hesburger asub ründama, McDonalds teeb kaevikuid / Andres Reimer

    Index Scriptorium Estoniae

    Reimer, Andres

    2005-01-01

    Hesburger tahab Eestis oma restoranide hulka kolmekordistada. McDonald's Eestis ei laiene, kuid kavatseb ettevõtte efektiivsust suurendada. Eesti hamburgerirestoranide kett Nehatu on konkurentsist välja langenud. Tabelid: Tulemused; Hamburgerirestoranid Eestis; Hamburger ja McDonald's maailmas. Lisad: Hakkas Hesburgeri partneriks; Hakka McDonald'si partneriks

  17. Riik teeb kunsti ostmise enda jaoks sunduslikuks / Mirko Ojakivi ; kommenteerinud Maarit Murka

    Index Scriptorium Estoniae

    Ojakivi, Mirko

    2009-01-01

    Kultuuriministeeriumis valmivast seaduseelnõust, mille kohaselt tuleb riigil ja kohalikel omavalitsustel avalikuks kasutamiseks mõeldud hoonete ehitamisel soetada kunsti ühe protsendi ulatuses hoone ehitusmaksumusest

  18. Jõhvi teeb j'älle Tallinnale ära / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2008-01-01

    Seoses Age Oksa balletikarjäärist loobumisega võiks Estonia teha sümboolse zhesti ja kutsuda nad oma lavale tantsima. Inglise Rahvuslikus Balletis tantsinud Age Oksa jaoks oli Estonia tema esimene koduteater

  19. Merkel: Euroopa Liit teeb Kreeka päästmiseks kõik endast oleneva

    Index Scriptorium Estoniae

    2011-01-01

    Saksamaa, Prantsusmaa ja Kreeka riigijuhid leppisid kokku, et alustavad uusi kõnelusi Kreeka võlakriisi üle. Euroopa Komisjon, Euroopa Keskpank ja Rahvusvaheline Valuutafond on valmis Kreekasse naasma

  20. Parim õpilasfirma teeb hieroglüüfidega kleepse / Helve Laasik

    Index Scriptorium Estoniae

    Laasik, Helve, 1958-

    2001-01-01

    Rahvusvahelise organisatsiooni Junior Achivement Arengufondi korraldatud õpilasfirmade võistlusel tunnistati parimaks Tallinna 21. Keskkooli õpilasfirma Valinor, kes valmistab riietele kantavaid hieroglüüfidega kleepse

  1. Eesti foto Londonis teeb meist "kuuma" riigi / Maris Lillak, Ann Alari

    Index Scriptorium Estoniae

    Lillak, Maris, 1970-

    2004-01-01

    Westminsteri parlamendihoones eesti fotonäitus "Similar Spaces" (Sarnased kohad - värsked fotod Eestist). Eksponeeritud Ly Lestbergi, Tarvo Hanno Varrese, Mare Tralla, Mark Raidpere, Raoul Kurvitza, Liina Siibi tööd. Kuraator Liina Siib

  2. Ilu Kondase seintel teeb tuju rõõmsaks / Tiina Sarv

    Index Scriptorium Estoniae

    Sarv, Tiina, 1949-

    2006-01-01

    Eesti Kunstiinstituudi moekunstnikuna lõpetanud, kuid raamatuillustraatorina tunnustust kogunud Viive Noore viimase kümne aasta loomingu näituse avamine Kondase keskuses. Väljas on Milvi Panga raamatuid "See, kes lustib" ja "Jõulust jaani" ning Leelo Tungla "Väikest jõulusoovi" illustratsioonid

  3. Mis teeb klassikast klassika / Eteri Kekelidze ; tõlk. Virge Harak

    Index Scriptorium Estoniae

    Kekelidze, Eteri, 1944-

    2007-01-01

    16. rahvusvahelisest teatrifestivalist "Baltiiski dom" ("Balti kodu") Peterburis : Anton Tshehhovi "Onu Vanja" (Belgia teater "Toneelhuis", lavastaja Luk Perceval), "Kolm õde" (lavastaja Rimas Tuminas), Goethe "Faust" (lavastaja Eimuntas Nekroshius), "Kosmos" (Witold Gombrowiczi romaani järgi lavastanud Jerzy Jarocki), Aleksandr Ostrovski "Mets" (Moskva Kunstiteater, lavastaja Kirill Serebrjannikov), Sergei Korobkovi "Phaidra. Kuldne koloss" (Moskva Rahvuste Teatri projekt, lavastaja Andrii Zholdak)

  4. Mõisahärra Puntila teeb komejanti / Mari Hiiemäe

    Index Scriptorium Estoniae

    Hiiemäe, Mari

    2009-01-01

    Bertolt Brechti näidend, mis kirjutatud Hella Wuolijoe jutustuste ja näidendikavandi järgi "Härra Punttila ja tema sulane Matti". Lavastaja Kalju Komissarov, esietendus 19. juunil Ugala tiigi kaldal

  5. Kui toit teeb haigeks / Anu Viita-Neuhaus ; kommenteerib Maie Jürisson

    Index Scriptorium Estoniae

    Viita-Neuhaus, Anu

    2010-01-01

    Toidu talumatusest ja allergiast: allergeenid; millised allergia diagnoosimise teste kasutatakse; allergia ravi. Kommenteerib Tallinna Lastehaigla Kesklinna Lastepolikliiniku nahaarst ja Eesti Allergialiidu juhataja Maie Jürisson

  6. Reconocimiento de las condiciones del mercado para el establecimiento de alianzas estratégicas de la Universidad de La Salle con empresas colombianas y mexicanas en la producción y comercialización del almidón nativo y resistente de Ñame, AR

    OpenAIRE

    Villarraga Vargas, Maria Eugenia; Rodríguez Villarraga, Ana Lucía

    2016-01-01

    Este trabajo busca reconocer las condiciones del mercado en Colombia y en otros países de la región, específicamente en México, para el establecimiento de alianzas de la Universidad de La Salle con el Gobierno Nacional, con el sector empresarial y académico así como con otras entidades públicas y privadas en la producción y comercialización del Almidón nativo y Resistente de Ñame (AR). Este trabajo está orientado a presentar alternativas de aprovechamiento del almidón de ñame obtenido en e...

  7. Results of a jet plume effects test on Rockwell International integrated space shuttle vehicle using a vehicle 5 configuration 0.02-scale model (88-OTS) in the 11 by 11 foot leg of the NASA/Ames Research Center unitary plan wind tunnel (IA19), volume 1

    Science.gov (United States)

    Nichols, M. E.

    1975-01-01

    Results are presented of jet plume effects test IA19 using a vehicle 5 configuration integrated space shuttle vehicle 0.02-scale model in the NASA/Ames Research Center 11 x 11-foot leg of the unitary plan wind tunnel. The jet plume power effects on the integrated vehicle static pressure distribution were determined along with elevon, main propulsion system nozzle, and solid rocket booster nozzle effectiveness and elevon hinge moments.

  8. Diversidad genética intra e inter-específica de ñame (Dioscorea spp. de la región Caribe de Colombia mediante marcadores AFLP

    Directory of Open Access Journals (Sweden)

    Hernando Javier Rivera-Jiménez

    2011-12-01

    Full Text Available Conocer la variabilidad genética del ñame, Dioscorea spp., permite apoyar estrategias de mejoramiento y conservación de este recurso fitogenético. El objetivo de este estudio fue la caracterización molecular de 20 accesiones de Dioscorea spp. mediante la técnica molecular de AFLP para determinar cómo se distribuye la variabilidad genética de manera intra e inter-específica. Los datos fueron analizados mediante los métodos de agrupación de correspondencia múltiple y análisis de similaridad de Dice, estableciendo los niveles de confiabilidad de los grupos genéticos mediante remuestreos. En términos de diversidad interespecífica, los valores promedios de similitud variaron entre 41.81% entre D. alata L. y D. rotundata Poir., y 33.51% entre D. trifida L.f. y D. esculenta (Lour. Burkill, lo que sugiere alta diversidad genética entre las accesiones estudiadas, que formaron cuatro grupos genéticos: D. alata, D. rotundata, D. esculenta y D. trifida, confirmando correspondencia entre la caracterización morfológica, clasificación botánica y la caracterización molecular. En términos de diversidad intraespecífica para la especie D. alata, el análisis también reveló una composición heterogénea en la región Caribe colombiana. Estos estudios ayudarán a definir una estrategia adecuada para fines de conservación y apoyar los esfuerzos futuros en los programas de mejoramiento genético.

  9. J ames Clerk Maxwell and his Equations

    Indian Academy of Sciences (India)

    gler maker' of the period whose students included G G Stokes, ... Besides reading with Hopkins, he also attended Stokes' lectures. ... This shrewd assess- ment was borne out later by several formulae advanced by. Maxwell where the results have proved to be correct but the mathematical arguments leading to them were ...

  10. Experiential learning: AMEE Guide No. 63.

    Science.gov (United States)

    Yardley, Sarah; Teunissen, Pim W; Dornan, Tim

    2012-01-01

    This Guide provides an overview of educational theory relevant to learning from experience. It considers experience gained in clinical workplaces from early medical student days through qualification to continuing professional development. Three key assumptions underpin the Guide: learning is 'situated'; it can be viewed either as an individual or a collective process; and the learning relevant to this Guide is triggered by authentic practice-based experiences. We first provide an overview of the guiding principles of experiential learning and significant historical contributions to its development as a theoretical perspective. We then discuss socio-cultural perspectives on experiential learning, highlighting their key tenets and drawing together common threads between theories. The second part of the Guide provides examples of learning from experience in practice to show how theoretical stances apply to clinical workplaces. Early experience, student clerkships and residency training are discussed in turn. We end with a summary of the current state of understanding.

  11. J ames Clerk Maxwell and his Equations

    Indian Academy of Sciences (India)

    He published in 1856 the essay on 'On the stability of the motion of Saturn's rings' which won him the Adams Prize. Maxwell as a Teacher. Maxwell was appointed to the Chair of Natural Philosophy at. Marischal College, Aberdeen in 1856. He held this appointment for three sessions until the professorship was suppressed.

  12. Study of the heavy ions (Au+Au at 150 AMeV) collisions with the FOPI detector. Comparison with the Landau-Vlasov model; Etude des collisions d`ions lourds AU+AU a 150 A.MeV avec le detecteur FOPI. Comparaison avec le modele de Landau-Vlasov

    Energy Technology Data Exchange (ETDEWEB)

    Boussange, S.

    1995-09-15

    In this thesis, heavy ions (Au+Au) collisions experiments are made at 150 AMeV.In the first part, a general study of the nuclear matter equation is presented. Then the used Landau-Vlasov theoretical model is describe. The third part presents the FOPI experience and the details of how to obtain this theoretical predictions (filter, cuts, corrections, possible centrality selections).At the end, experimental results and comparisons with the Landau-Vlasov model are presented. (TEC). 105 refs., 96 figs., 14 tabs.

  13. Results of an investigation to determine local flow characteristics at the air data probe locations using an 0.030-scale model (45-0) of the space shuttle vehicle orbiter configuration 140A/B (modified) in the NASA Ames Research Center unitary plan wind tunnel (OA161, A, B, C), volume 1

    Science.gov (United States)

    Nichols, M. E.

    1976-01-01

    Results are presented of wind tunnel test 0A161 of a 0.030-scale model 45-0 of the configuration 140A/B (modified) space shuttle vehicle orbiter in the NASA Ames Research Center Unitary Plan Wind Tunnel facilities. The purpose of this test was to determine local total and static pressure environments for the air data probe locations and relative effectiveness of alternate flight-test probe configurations. Testing was done in the Mach number range from 0.30 to 3.5. Angle of attack was varied from -8 to 25 degrees while sideslip varied between -8 and 8 degrees.

  14. Telelegend Leo Karpin : ETV uus juhtkond teeb vaid lammutustööd / Leo Karpin ; interv. Verni Leivak

    Index Scriptorium Estoniae

    Karpin, Leo, 1946-2014

    2004-01-01

    Pea 40 aastat Eesti Televisioonis töötanud telerežissöör oma teletöölt lahkumise põhjustest. Lisaks kommentaar "ETV juhatuse esimees Ilmar Raag, miks tunnustatud telemees Leo Karpin ametist vabastati?"

  15. Erkki Raasuke : mind teeb kohutavalt murelikuks üha süvenev sahkerdamine / Erkki Raasuke ; interv. Mikk Salu

    Index Scriptorium Estoniae

    Raasuke, Erkki, 1971-

    2006-01-01

    Hansapanga Grupi juht näeb Eesti majanduses ülekuumenemist ning loodab, et majanduskasvu langemine 6-8% juurde tuleb pehmelt. Liiga kiire palgakasv seab ohtu eksportivad ettevõtted. Ta nimetab neli faktorit, mis võiksid meie pikemaajalist majanduskasvu ohustada

  16. Veiko Õunpuu : võitmine teeb asja lihtsamaks / Veiko Õunpuu ; interv. Andris Feldmanis

    Index Scriptorium Estoniae

    Õunpuu, Veiko, 1972-

    2007-01-01

    Eesti mängufilm "Sügisball" (režissöör Veiko Õunpuu, produtsent Katrin Kissa) sai Venezia 64. filmifestivali konkursiprogrammi Orizzonti peaauhinna. Lühiintervjuu filmi režissööriga kohapeal

  17. Vormiriietus teeb koolilapse shikiks ja paneb väärikalt käituma / Sandra Maasalu

    Index Scriptorium Estoniae

    Maasalu, Sandra

    2008-01-01

    Eesti koolides kantavatest koolivormidest. Pikemalt Katrin Kivi disainitud Tallinna Saksa gümnaasiumi koolivormist ja Tallinna Arte gümnaasiumi koolivormist. Katrin Kivi ja Peeter Kreitzbergi kommentaarid. 8 ill.

  18. Mida teeb sinu organisatsioon, et olla keskkonnasõbralik? / Liis Elmi, Monika Kuzmina, Kairit Kolskar, Kristina Toms...[jt.

    Index Scriptorium Estoniae

    2008-01-01

    Küsimusele vastavad: BEST-Esonia juhatuse liige Liisi Elmi, Rahvaliidu Noored juhatuse esimees Monika Kuzmina, Noored Sotsiaaldemokraadid president Kairit Kolskar, AIESEC president Kristina Toms, Eesti Psühholoogiaüliõpilaste Ühenduse juhatuse liige Andres Vegel

  19. Tõuni imekitarr kõlab nagu mesi . Pedaal-steel teeb popmuusikas taassündi / Rando Tooming

    Index Scriptorium Estoniae

    Tooming, Rando

    2009-01-01

    Muusik Tõnu Timm jutustab loo, kuidas hankis Ameerikast haruldase pedaal-steel- kitarri. Eesti kasutusel olevatest vanematest pedaal-steel-kitarridest. Ansamblid, kus kasutatakse kõneall olevat kitarri

  20. M.O.T.T. - Kreeka teeb läbi pankroti ja kõik on rahul / Raimo Poom

    Index Scriptorium Estoniae

    Poom, Raimo

    2011-01-01

    Euroala liidrite tippkohtumisel otsustati pikendada Kreekale tulevikus antavate EFSF-laenude tähtaegu, samuti lubati alandada Kreekale antavate laenude intresse ja pikendada ka juba 2010. a. kokkulepitud abiprogrammist saadavate laenude tähtaegu. Rahaturud reageerisid tippkohtumisel saavutatud kokkuleppele üllatavalt positiivselt. Eestit esindas kohtumisel president Toomas Hendrik Ilves. Rahandusminister Jürgen Ligi kommentaare

  1. Economics of Seed Yam Production Using Minisett Technique in Oyo State, Nigeria Economie de la production de semences d’igname à l’aide de la technique des minisetts dans l’Etat d’Oyo, au Nigéria Economía de la producción de semilla de ñame mediante la técnica «minisett» en el Estado de Oyo de Nigeria

    Directory of Open Access Journals (Sweden)

    Oguntade Adegboyega Eyitayo

    2011-01-01

    statistiques descriptives. La structure des coûts de production a été analysée à l’aide de pourcentages, tandis que l’analyse de la marge brute a permis de déterminer la rentabilité de la production de semences d’ignames à l’aide de la technique des minisetts. Les résultats de cette analyse ont montré que la production de semences d’ignames était dominée par les hommes. Chez les producteurs, la taille moyenne du ménage était de 7,7 personnes, la taille médiane de 7,0 personnes et la taille modale de 7 personnes. La plupart des producteurs étaient instruits et avaient d’autres métiers. Les producteurs ont évalué la technique comme bonne, très bonne ou excellente. Le revenu par hectare de production de semences d’igname s’élevait à 337 500 N. Le coût total de production était de 150 500 N tandis que le coût par semence d’igname s’élevait à 16,72 N. Pour chaque naira investi dans la production de semences d’igname utilisant la technique des minisetts, les producteurs sont donc censés obtenir un revenu net de 1,24 N. Cela montre que la production de semences d’igname à l’aide de la technique des minisetts était une activité rentable dans la région couverte par l’étude. Les coûts de main-d’œuvre représentaient à eux seuls 78,1 % du coût total de production. Il est donc nécessaire de déployer les techniques appropriées pour réduire ces coûts, et ainsi réduire les coûts de production et accroître la rentabilité de la production de semences d’igname à l’aide de la technique des minisetts.El estudio evalúa la economía de la producción de semilla de ñame usando la tecnología «minisett» en el Estado de Oyo, al sudeste de Nigeria. El análisis se basa en los datos de entrada y salida recabados a partir de sesenta cultivadores de ñame (Dioscorea spp. y del precio de mercado existente en la zona. Las características socioeconómicas de los participantes en el estudio se analizan mediante la estad

  2. Cassava, yam, sweet potato and ñampi starch: functional properties and possible applications in the food industry. Harinas y almidones de yuca, ñame, camote y ñampí: propiedades funcionales y posibles aplicaciones en la industria alimentaria.

    Directory of Open Access Journals (Sweden)

    Pedro Vargas Aguilar

    2013-03-01

    Full Text Available A technical review was conducted to related physical and chemical properties of flours and starches from cassava, yams, taro and sweet potato. Amyloseamylopectin content, viscosity, nutritional value and fiber, were studied to relate them with starch functional properties. A relationship was obtained between amylose-amylopectin, viscosity and fiber content with the digestibility of those starches and the glycemic index values. The use of fermentation to enhance the nutritional value of these starches is known. Starch fermentation allows the production of gluten-free bread and energy drinks as an option to diversify products. It was also observed the relationship between the starch viscosity and the fat absorption in fried foods.Se realizó una revisión de las características fisicoquímicas de las harinas y almidones de yuca, ñame, ñampí y camote, tales como el contenido de amilosa-amilopectina, la viscosidad, el valor nutricional y la fibra, con el fin de relacionarlas con sus propiedades funcionales y técnico-funcionales. Se obtuvo una relación entre el contenido de amilosa-amilopectina, viscosidad y contenido de fibra en la digestibilidad de estos almidones y los valores de índice glicémico. Se encontró que es posible introducir modificaciones por medio de la fermentación para mejorar el valor funcional de estos almidones. La fermentación permite elaborar pan sin gluten y bebidas energéticas como nuevas opciones de productos. También se encontró que existe una relación entre la viscosidad de los almidones y la disminución de absorción de la grasa en frituras.

  3. Polymer materials research at NASA Ames Research Center

    Science.gov (United States)

    Parker, J. A.; Heimbuch, A. H.; Gilwee, W. J.

    1982-01-01

    Polymers that provide significant improvements in both efficiency and safety for civilian transport aircraft and military combat aircraft were developed. High strength to weight structures such as carbon fiber composites with long term durability are requirements common to both classes of aircraft. Aircraft safety improvements in fire resistance and crashworthiness of primary and secondary structures are long term objectives for transport aircraft. Void filler ballistic foams, intumescent coatings, and radiation-resistant transparent plastics contribute to vulnerability reduction in combat military aircraft. Low and high velocity impact tolerance, fire resistance, thermal stability, and long term durability of polymers and components are emphasized.

  4. Theoretical insights into interprofessional education: AMEE Guide No. 62.

    Science.gov (United States)

    Hean, Sarah; Craddock, Deborah; Hammick, Marilyn; Hammick, Marilyn

    2012-01-01

    In this Guide, we support the need for theory in the practice of interprofessional education and highlight a range of theories that can be applied to interprofessional education. We specifically discuss the application of theories that support the social dimensions of interprofessional learning and teaching, choosing by way of illustration the theory of social capital, adult learning theory and a sociological perspective of interprofessional education. We introduce some of the key ideas behind each theory and then apply these to a case study about the development and delivery of interprofessional education for pre-registration healthcare sciences students. We suggest a model that assists with the management of the numerous theories potentially available to the interprofessional educator. In this model, context is central and a range of dimensions are presented for the reader to decide which, when, why and how to use a theory. We also present some practical guidelines of how theories may be translated into tangible curriculum opportunities. Using social capital theory, we show how theory can be used to defend and present the benefits of learning in an interprofessional group. We also show how this theory can guide thinking as to how interprofessional learning networks can best be constructed to achieve these benefits. Using adult learning theories, we explore the rationale and importance of problem solving, facilitation and scaffolding in the design of interprofessional curricula. Finally, from a sociological perspective, using Bernstein's concepts of regions and terrains, we explore the concepts of socialisation as a means of understanding the resistance to interprofessional education sometimes experienced by curriculum developers. We advocate for new, parallel ways of viewing professional knowledge and the development of an interprofessional knowledge terrain that is understood and is contributed to by all practitioners and, importantly, is centred on the needs of the patient or client. Through practical application of theory, we anticipate that our readers will be able to reflect and inform their current habitual practices and develop new and innovative ways of perceiving and developing their interprofessional education practice.

  5. Topography and surface sediment distribution around Amee shoal Mormugao

    Digital Repository Service at National Institute of Oceanography (India)

    Ambre, N.V.

    stream_size 3 stream_content_type text/plain stream_name Recent_Adv_Mar_Archaeol_1991_113.pdf.txt stream_source_info Recent_Adv_Mar_Archaeol_1991_113.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 ...

  6. Development of the Adolescent Measure of Empathy and Sympathy (AMES)

    NARCIS (Netherlands)

    Vossen, Helen G M|info:eu-repo/dai/nl/297706632; Piotrowski, Jessica T.; Valkenburg, Patti M.

    2015-01-01

    The aim of the present study was to develop and validate a new instrument to measure empathy and sympathy in adolescents that differentiates between empathy and sympathy, and balances its emphasis on affective and cognitive empathy. The psychometric properties of the Adolescent Measure of Empathy

  7. NASA Ames Summer High School Apprenticeship Research Program

    Science.gov (United States)

    1988-09-01

    be done. It was estimated that the entire project will cost approximately eight billion dollars. Under the leadershp of Phillip Culbertson and John...34safe haven," an emergency supply of food, water, clothing, life support systems, and waste management systems. This standard pack of supplies will be...involved in the process that produces suckdown, this basic theory of infinite suckdown is valid. The fact that lower heights increase suckdown

  8. Automatic speech recognition research at NASA-Ames Research Center

    Science.gov (United States)

    Coler, Clayton R.; Plummer, Robert P.; Huff, Edward M.; Hitchcock, Myron H.

    1977-01-01

    A trainable acoustic pattern recognizer manufactured by Scope Electronics is presented. The voice command system VCS encodes speech by sampling 16 bandpass filters with center frequencies in the range from 200 to 5000 Hz. Variations in speaking rate are compensated for by a compression algorithm that subdivides each utterance into eight subintervals in such a way that the amount of spectral change within each subinterval is the same. The recorded filter values within each subinterval are then reduced to a 15-bit representation, giving a 120-bit encoding for each utterance. The VCS incorporates a simple recognition algorithm that utilizes five training samples of each word in a vocabulary of up to 24 words. The recognition rate of approximately 85 percent correct for untrained speakers and 94 percent correct for trained speakers was not considered adequate for flight systems use. Therefore, the built-in recognition algorithm was disabled, and the VCS was modified to transmit 120-bit encodings to an external computer for recognition.

  9. Mechanical design of NASA Ames Research Center vertical motion simulator

    Science.gov (United States)

    Engelbert, D. F.; Bakke, A. P.; Chargin, M. K.; Vallotton, W. C.

    1976-01-01

    NASA has designed and is constructing a new flight simulator with large vertical travel. Several aspects of the mechanical design of this Vertical Motion Simulator (VMS) are discussed, including the multiple rack and pinion vertical drive, a pneumatic equilibration system, and the friction-damped rigid link catenaries used as cable supports.

  10. Grounded theory in medical education research: AMEE Guide No. 70.

    Science.gov (United States)

    Watling, Christopher J; Lingard, Lorelei

    2012-01-01

    Qualitative research in general and the grounded theory approach in particular, have become increasingly prominent in medical education research in recent years. In this Guide, we first provide a historical perspective on the origin and evolution of grounded theory. We then outline the principles underlying the grounded theory approach and the procedures for doing a grounded theory study, illustrating these elements with real examples. Next, we address key critiques of grounded theory, which continue to shape how the method is perceived and used. Finally, pitfalls and controversies in grounded theory research are examined to provide a balanced view of both the potential and the challenges of this approach. This Guide aims to assist researchers new to grounded theory to approach their studies in a disciplined and rigorous fashion, to challenge experienced researchers to reflect on their assumptions, and to arm readers of medical education research with an approach to critically appraising the quality of grounded theory studies.

  11. The integrated curriculum in medical education: AMEE Guide No. 96.

    Science.gov (United States)

    Brauer, David G; Ferguson, Kristi J

    2015-04-01

    The popularity of the term "integrated curriculum" has grown immensely in medical education over the last two decades, but what does this term mean and how do we go about its design, implementation, and evaluation? Definitions and application of the term vary greatly in the literature, spanning from the integration of content within a single lecture to the integration of a medical school's comprehensive curriculum. Taking into account the integrated curriculum's historic and evolving base of knowledge and theory, its support from many national medical education organizations, and the ever-increasing body of published examples, we deem it necessary to present a guide to review and promote further development of the integrated curriculum movement in medical education with an international perspective. We introduce the history and theory behind integration and provide theoretical models alongside published examples of common variations of an integrated curriculum. In addition, we identify three areas of particular need when developing an ideal integrated curriculum, leading us to propose the use of a new, clarified definition of "integrated curriculum", and offer a review of strategies to evaluate the impact of an integrated curriculum on the learner. This Guide is presented to assist educators in the design, implementation, and evaluation of a thoroughly integrated medical school curriculum.

  12. ame. In anzini, ilm and ed from etrieved n, 20

    African Journals Online (AJOL)

    Precious

    person sufficiently enough, a series of rituals and dances are performed and one of such rituals is the .... music and dance, conscientization, sensitization, ritual displays, and above all, to bring in spiritual messages from ..... and Arab civilizations are secondary to the Igala culture. The Igala knowledge of nature, supernatural ...

  13. Pros and Cons amification and aming in Classroom

    Directory of Open Access Journals (Sweden)

    Iulian Furdu

    2017-07-01

    Full Text Available The aim of the current work is to assess the challenges that gamification in education are facing nowadays. Benefits and disadvantages of using gamification in classroom are both discussed to offer a clearer view on the impact of using gamification within learning process. Exploratory study –cases are provided to investigate the relation between motivation and engagement of the students and gamification in training. Following this idea, a survey was conducted to assess how students’ behavior and motivation is affected by introducing a single, specific gamification element during a semester learning process. To stimulate competition among students, a ranking type plugin was introduced within the university learning management system used for extramural education. The results prove that motivation decreases by comparison to the previous semester.

  14. CARACTERÍSTICAS FISICOQUÍMICAS Y MORFOLÓGICAS DE RIZÓFOROS DE ÑAME (Dioscorea alata CARACTERÍSTICAS FÍSICOQUÍMICAS E MORFOLÓGICAS DE RIZÓFOROS DE INHAME (Dioscorea alata PHYSICOCHEMICAL AND MORPHOLOGIC CHARACTERISTICS OF THE RIZÓFOROS OF YAM (Dioscorea alata

    Directory of Open Access Journals (Sweden)

    CLÁUDIA DENISE DE PAULA

    2012-12-01

    Full Text Available En este trabajo se determino la composición físico-química y las características morfológicas de los rizóforos de seis variedades de ñame (Dioscorea alata del Banco de Germoplasma de Hortalizas (BGH de la Universidade Federal de Viçosa (UFV. Fue determinada la composición centesimal mediante análisis de humedad, lípidos, proteína, cenizas, fibra bruta y carbohidratos. Las características morfológicas fueron estudiadas visualmente y por análisis microscópicos. La composición físico-química presento diferencias significativas (pNeste trabalho determinou-se a composição físico-química e características morfológicas dos rizóforos de seis variedades de inhame (Dioscorea alata do Banco de Germoplasma de Hortaliças (BGH da Universidade Federal de Viçosa (UFV. Foi determinada a composição centesimal mediante análises de umidade, lipídios, proteína, cinzas, fibra bruta e carboidratos. As características morfológicas foram estudadas através do aspecto visual e análises microscópicas. A composição físico-química apresentou diferenças significativas (pIn this paper we determine the physico-chemical and morphological characteristics of the rizóforos of six yam varieties (Dioscorea alafa from the Vegetable Germplasm Bankb (BGH, Universidade Federal de Viçosa (UFV. Proximate composition was determined by analysis of humidity, fat, protein, ash, crude fiber and carbohydrates. The morphological characteristics were studied visually and by microscopic analysis. The physical and chemical composition showed significant differences (p<0.05 for all features, except for lipids. The Florida variety stood out from the others by presenting higher values of ash (3.08 g/100g, protein (6.35 g/100g fiber (2.69 g/100g and lower total carbohydrate content. Visual assessment of the rizóforos varieties showed that Florida, San Tome and Mimoso were those with the most regular forms. According to the scanning electron micrograph, the

  15. "Rehepapp" jõuab kinolinale / Sulev Vedler

    Index Scriptorium Estoniae

    Vedler, Sulev, 1970-

    2004-01-01

    Eesti Filmi Sihtasutus teeb peagi teatavaks täispikkade mängufilmide arendustoetuse saajad. Rudolf Konimois Film kavatseb tuua ekraanile Andrus Kivirähki "Rehepapi", stsenaariumi teeb Rainer Sarnet. Lisaks ülevaade "Mida eestlased tahavad filmida?"

  16. Mis teeb ühe brand'i teistest paremaks? : Võidu tähendusrikkuse poole / Mauri Sööt

    Index Scriptorium Estoniae

    Sööt, Mauri

    2013-01-01

    Balti riikides läbi viidud brand'iuuringust Meaningful Brands, millega selgitati, kuidas brand'id mõjutavad inimese heaolu individuaalses ja kollektiivses tähenduses. Eestis uuritud 46 brand'i seas saavutas kõige kõrgema tähendusrikkuse indeksi magusatootja Kalev. Uuringutulemuste kasutusvõimalusi ettevõtte kommunikatsioonis ja üritusturunduses

  17. Maria Listra teeb oma häälega tööd, et teada, kuidas “instrument” töötab / interv. Kristjan Roos

    Index Scriptorium Estoniae

    Listra, Maria, 1989-

    2012-01-01

    Maria Listra on Eesti muusikasõpradele teada juba sellest ajast, kui ta oli kolmeaastane. Kuigi praegu tegutseb lauljatar Londonis, ei ole ta unustanud ka oma kodumaad. Just täna alustab ta keelpillikvartetiga Prezioso kontserdituuri “Vaid see on armastus”

  18. Mida teeb Narva kutseõppekeskus teie arvates Narva linna heaks? / Burkina, Irina; Patlep, Kaarel; Kaalik, Ljubov; Dolgovskaja, Tatjana; Ibragimov, Muret; Vorobjova, Anna

    Index Scriptorium Estoniae

    2007-01-01

    Vastavad Narva Kutseõppekeskuse kutseõpetajad Irina Burkina, Tatjana Dolgovskaja ja Murat Ibragimov ning autovaldkonna juht Kaarel Patlep, projektijuht Ljubov Kaalik ja PR-spetsialist Anna Vorobjova

  19. Lembit-Kaur Stöör teeb isevärki maju / Lembit-Kaur Stöör ; interv. Epp Lankots

    Index Scriptorium Estoniae

    Stöör, Lembit-Kaur, 1976-

    2008-01-01

    Büroos KOKO Arhitektid töötav arhitekt L.-K. Stöör A. Kõresaare ja R. Kotovi poolt asutatud büroost, oma eeskujudest arhitektuuris, Tallinna Inglise Kolledzhi juurdeehitusest (koos M. Maistega, sisearhitektid: L. Lindvere, L. Murula, R. Paling), konstruktor T. Tammerik), 2007. a. Kultuurkapitali arhitektuuri sihtkapitali objektibreemia võitnud Tallinna sünagoogist (koos Tõnis Kimmeliga, sisearhitektid: L. Lindvere, R. Paling), Kuldala elamurajoonist (koos M. Maistega)

  20. Adult learning theories: implications for learning and teaching in medical education: AMEE Guide No. 83.

    Science.gov (United States)

    Taylor, David C M; Hamdy, Hossam

    2013-11-01

    There are many theories that explain how adults learn and each has its own merits. This Guide explains and explores the more commonly used ones and how they can be used to enhance student and faculty learning. The Guide presents a model that combines many of the theories into a flow diagram which can be followed by anyone planning learning. The schema can be used at curriculum planning level, or at the level of individual learning. At each stage of the model, the Guide identifies the responsibilities of both learner and educator. The role of the institution is to ensure that the time and resources are available to allow effective learning to happen. The Guide is designed for those new to education, in the hope that it can unravel the difficulties in understanding and applying the common learning theories, whilst also creating opportunities for debate as to the best way they should be used.

  1. The place of anatomy in medical education: AMEE Guide no 41.

    Science.gov (United States)

    Louw, Graham; Eizenberg, Norman; Carmichael, Stephen W

    2009-05-01

    This Guide, a combined work by three authors from different countries, provides perspectives into the history of teaching gross anatomy, briefly, from the earliest of times, through to a detailed examination of curricula in both traditional didactic approaches and Problem-Based Learning (PBL) curricula. The delivery of a module within a curriculum in tertiary education is interplay between the content (knowledge and skills) of a subject, the teaching staff involved, the students and their approaches to learning, and the philosophy underpinning the delivery of the learning material. The work is divided into sections that deal with approaches to learning anatomy from the perspective of students, to delivery of the content of the curriculum by lecturers, including the assessment of knowledge, and itemises the topics that could be considered important for an appropriate anatomy module in an integrated course, delivered in a way that emphasises clinical application. The work concludes by looking to the future, and considering what measures may need to be addressed to ensure the continued development of anatomy as a clinically relevant subject in any medical curriculum.

  2. Situational judgement tests in medical education and training: Research, theory and practice: AMEE Guide No. 100.

    Science.gov (United States)

    Patterson, Fiona; Zibarras, Lara; Ashworth, Vicki

    2016-01-01

    Why use SJTs? Traditionally, selection into medical education professions has focused primarily upon academic ability alone. This approach has been questioned more recently, as although academic attainment predicts performance early in training, research shows it has less predictive power for demonstrating competence in postgraduate clinical practice. Such evidence, coupled with an increasing focus on individuals working in healthcare roles displaying the core values of compassionate care, benevolence and respect, illustrates that individuals should be selected on attributes other than academic ability alone. Moreover, there are mounting calls to widen access to medicine, to ensure that selection methods do not unfairly disadvantage individuals from specific groups (e.g. regarding ethnicity or socio-economic status), so that the future workforce adequately represents society as a whole. These drivers necessitate a method of assessment that allows individuals to be selected on important non-academic attributes that are desirable in healthcare professionals, in a fair, reliable and valid way. What are SJTs? Situational judgement tests (SJTs) are tests used to assess individuals' reactions to a number of hypothetical role-relevant scenarios, which reflect situations candidates are likely to encounter in the target role. These scenarios are based on a detailed analysis of the role and should be developed in collaboration with subject matter experts, in order to accurately assess the key attributes that are associated with competent performance. From a theoretical perspective, SJTs are believed to measure prosocial Implicit Trait Policies (ITPs), which are shaped by socialisation processes that teach the utility of expressing certain traits in different settings such as agreeable expressions (e.g. helping others in need), or disagreeable actions (e.g. advancing ones own interest at others, expense). Are SJTs reliable, valid and fair? Several studies, including good quality meta-analytic and longitudinal research, consistently show that SJTs used in many different occupational groups are reliable and valid. Although there is over 40 years of research evidence available on SJTs, it is only within the past 10 years that SJTs have been used for recruitment into medicine. Specifically, evidence consistently shows that SJTs used in medical selection have good reliability, and predict performance across a range of medical professions, including performance in general practice, in early years (foundation training as a junior doctor) and for medical school admissions. In addition, SJTs have been found to have significant added value (incremental validity) over and above other selection methods such as knowledge tests, measures of cognitive ability, personality tests and application forms. Regarding differential attainment, generally SJTs have been found to have lower adverse impact compared to other selection methods, such as cognitive ability tests. SJTs have the benefit of being appropriate both for use in selection where candidates are novices (i.e. have no prior role experience or knowledge such as in medical school admissions) as well as settings where candidates have substantial job knowledge and specific experience (as in postgraduate recruitment for more senior roles). An SJT specification (e.g. scenario content, response instructions and format) may differ depending on the level of job knowledge required. Research consistently shows that SJTs are usually found to be positively received by candidates compared to other selection tests such as cognitive ability and personality tests. Practically, SJTs are difficult to design effectively, and significant expertise is required to build a reliable and valid SJT. Once designed however, SJTs are cost efficient to administer to large numbers of candidates compared to other tests of non-academic attributes (e.g. personal statements, structured interviews), as they are standardised and can be computer-delivered and machine-marked.

  3. Isotope analysis in 32S +58,64Ni at 14.5 AMeV

    International Nuclear Information System (INIS)

    In recent years isospin effects in heavy ion nuclear reactions and in particular in thermodynamical observables have been studied in several laboratories. The scientific program of the NUCL-EX collaboration concerns the investigation of these effects in particular at low energies, corresponding to the opening of the multifragmentation mechanism. At these energies, corresponding to the highest range of the Tandem-ALPI complex at the Legnaro Laboratories, the hot and excited composite systems formed in heavy ion nuclear reactions enter in the liquid-gas coexistence region. A very interesting point is to extract the excitation energies and the temperatures for systems differing only in N/Z ratio since differences could be seen in the limiting temperature values, i.e. the maximal temperature a system can sustain while evaporating

  4. Low-Speed Wind Tunnel Testing of the NPS/NASA Ames Mach 6 Optimized Waverider

    Science.gov (United States)

    1994-06-16

    ntwof * 5000! VEX A - axialf * 5000! / VEX S1 - sonel * 50001 / VEX S? - stwol * 5000! / VEX R - rmf * 416.67f / VEX 600 IF nonel >- 0 THEN GOTO 1000...0.637985 0.034399 0.000264 90 -3.109447 0.185533 -0.160018 -0.575876 0.031314 -0.000202 81 JET.r RUN ISO , 2: TUNNEL PARAMETERS Ap = 5.50 cm H20 q = 12.1

  5. Cognitive Load Theory: implications for medical education: AMEE Guide No. 86.

    Science.gov (United States)

    Young, John Q; Van Merrienboer, Jeroen; Durning, Steve; Ten Cate, Olle

    2014-05-01

    Cognitive Load Theory (CLT) builds upon established models of human memory that include the subsystems of sensory, working and long-term memory. Working memory (WM) can only process a limited number of information elements at any given time. This constraint creates a "bottleneck" for learning. CLT identifies three types of cognitive load that impact WM: intrinsic load (associated with performing essential aspects of the task), extraneous load (associated with non-essential aspects of the task) and germane load (associated with the deliberate use of cognitive strategies that facilitate learning). When the cognitive load associated with a task exceeds the learner's WM capacity, performance and learning is impaired. To facilitate learning, CLT researchers have developed instructional techniques that decrease extraneous load (e.g. worked examples), titrate intrinsic load to the developmental stage of the learner (e.g. simplify task without decontextualizing) and ensure that unused WM capacity is dedicated to germane load, i.e. cognitive learning strategies. A number of instructional techniques have been empirically tested. As learners' progress, curricula must also attend to the expertise-reversal effect. Instructional techniques that facilitate learning among early learners may not help and may even interfere with learning among more advanced learners. CLT has particular relevance to medical education because many of the professional activities to be learned require the simultaneous integration of multiple and varied sets of knowledge, skills and behaviors at a specific time and place. These activities possess high "element interactivity" and therefore impose a cognitive load that may surpass the WM capacity of the learner. Applications to various medical education settings (classroom, workplace and self-directed learning) are explored.

  6. The Objective Structured Clinical Examination (OSCE): AMEE Guide No. 81. Part II: organisation & administration.

    Science.gov (United States)

    Khan, Kamran Z; Gaunt, Kathryn; Ramachandran, Sankaranarayanan; Pushkar, Piyush

    2013-09-01

    The organisation, administration and running of a successful OSCE programme need considerable knowledge, experience and planning. Different teams looking after various aspects of OSCE need to work collaboratively for an effective question bank development, examiner training and standardised patients' training. Quality assurance is an ongoing process taking place throughout the OSCE cycle. In order for the OSCE to generate reliable results it is essential to pay attention to each and every element of quality assurance, as poorly standardised patients, untrained examiners, poor quality questions and inappropriate scoring rubrics each will affect the reliability of the OSCE. The validity will also be influenced if the questions are not realistic and mapped against the learning outcomes of the teaching programme. This part of the Guide addresses all these important issues in order to help the reader setup and quality assure their new or existing OSCE programmes.

  7. Quantitative and qualitative methods in medical education research: AMEE Guide No 90: Part I.

    Science.gov (United States)

    Tavakol, Mohsen; Sandars, John

    2014-09-01

    Medical educators need to understand and conduct medical education research in order to make informed decisions based on the best evidence, rather than rely on their own hunches. The purpose of this Guide is to provide medical educators, especially those who are new to medical education research, with a basic understanding of how quantitative and qualitative methods contribute to the medical education evidence base through their different inquiry approaches and also how to select the most appropriate inquiry approach to answer their research questions.

  8. Top five medical innovations in China mainland since Xinhai revolution [1911]: results of AME survey-002.

    Science.gov (United States)

    Wáng, Yì-Xiáng J; Xiao, Fan

    2015-06-01

    This survey aims to scrutinize important medical innovations in Chinese mainland since Xinhai (Hsin-hai) revolution in 1911, which marked the end of Manchurian imperial rule and the beginning of China's republican era. An online cross-sectional survey was carried out during the period of Dec 29, 2014 to Feb 5, 2015, totaling 37 days. The survey was conducted on the platform provided by DXY (www.dxy.cn), which is the largest medical and paramedical related website in China. An email was sent to all DXY registered users to invite them to participate in a 5-minute survey. The participants were asked to nominate up to four important medical innovations in China mainland since Xinhai revolution. The participant could select 'zero' which means he/she felt there was no important medical innovations, or he/she did not know important medical innovations. It was noted that important medical innovations refer to (I) those with practical and almost immediate significance to improve healthcare; (II) should not only be introducing western technique to China, but those involve major improvement of existing western techniques count; (III) should not be those with important theoretical discovery but did not have almost immediate significance to improve healthcare. In total 1,513 DXY users participated in the voting. Totally 489 (32.3%), 441 (29.1%), 342 (22.6%), 150 (9.9%), 91 (6.0%) participants provided 0, 1, 2, 3, 4 nominations respectively. (I) Artemisine (Qinghaosu) for malaria treatment (Project 523 team, 1972); (II) arsenic Trioxide (As2O3) for acute promyelocytic leukemia (APL) treatment (ZHANG Ting-Dong and colleagues, 1970s); (III) limb re-plantation (CHEN Zhong-Wei and colleagues, 1963); (IV) all-trans retinoic acid (ATRA) for APL treatment (WANG Zhen-Yi and colleagues, 1988); and (V) Wu's mask for plague prevention (WU Lien-The, 1910), were voted as the top five innovations in China mainland since Xinhai revolution, with 375, 96, 91, 53, and 8 votes respectively. In this voting exercise, five achievements were voted as top innovations in China mainland since Xinhai revolution. However, only ATRA for APL treatment was accomplished after the ending of Great Proletarian Cultural Revolution in year 1976 in China.

  9. Investigation of the NREL NASA/Ames Wind Turbine Aerodynamics Database

    Energy Technology Data Exchange (ETDEWEB)

    Aahlund, Karin [Swedish Defence Research Agency, Stockholm (Sweden)

    2006-06-15

    The original purpose of the project was to compare two-dimensional and three-dimensional behaviour of aerodynamic coefficients on wind turbines. Because of missing information in the database, the angle of attack distribution (AD) must first be calculated. The probes that were attached to the leading edge on one of the two blades were expected to lead to the AD. This was shown to be a difficult task. Three different attempts were made to calculate the AD. Since low angles of attack follow two-dimensional patterns, the AD could be calculated. The interesting area at high angles of attack, where the three-dimensional effects are strong, could not be evaluated. For all similar experiments, the velocity of the air that passes through the turbine must be measured. Then the AD along a blade can easily be calculated.

  10. English language usage pattern in China mainland doctors: AME survey-001 initial analysis results.

    Science.gov (United States)

    Zhang, Zhongheng; Wáng, Yì-Xiáng J

    2015-02-01

    English is the most widely used language in medical community worldwide. Till now there is no study yet on how English language is being used among mainland Chinese doctors. The present survey aimed to address this question. An online cross-sectional survey was carried out during the period of 23 Oct 2014 to 13 November 2014, totaling 22 days. This survey was conducted on the platform provided by DXY (www.dxy.cn), which is the largest medical and paramedical related website in China with registered medical doctor users of slightly more than one million. E-mails were sent to all DXY registered users to invite them to participate the survey which lasts approximately five-minute. The questionnaire included three major aspects: (I) the demographic characteristics of participants; (II) English reading pattern; and (III) paper publishing experience in international journals. To accommodate the complexity of relationships among variables, structural equation modeling (SEM) was employed to build the model. In total 1,663 DXY users completed the survey, which counted for ≈1% of the total registered medical doctor users. There were more participants from relatively economically developed eastern coast areas. The age of participants was 33.6±7.4 years. There were 910 respondents from teaching hospitals (54.72%), followed by tertiary care hospitals (class-III hospital, 22.37%). Mainland Chinese doctors were more likely to consult medical materials in Chinese (63.5%) when they encounter clinical difficulties. Participants who were able to list English journals of their own specialty up to four were 44.02% for 0, 13.77% for one journal, 13.89% for two journals, 9.26% for three journals, and 19.06% for four journals. Most participants (82.86%) have read at least one English paper or one professional book in English, while 17.14% responded they never read a single English paper or professorial book in English. About 30.42% participants published at least one paper in English journals, and approximately half of them require professional English editing service. This limited survey shows Mainland Chinese doctors are more likely to use Chinese medical materials. Overall their familiarity with international English journals is relatively low. Improving English education at the undergraduate and post-graduate levels is recommended.

  11. NATO Handbook on the Medical Aspects of NBC Defensive Operations AMedP-6(B)

    Science.gov (United States)

    1996-02-01

    Differential diagnosis may require toxin detection. Gas chromatographic analysis of food or stomach contents can rule out pesticide exposure. (3...Specific Laboratory Tests. Diagnosis is confirmed by detection of toxin in the food, water, stomach contents or environmental samples. Saxitoxin...whether due to a single large exposure or to repeated smaller exposures), there may follow abdominal cramps, increased peristalsis , vomiting, diarrhoea

  12. Inverse-kinematics study of 78Kr + 40Ca at 10 AMeV

    Directory of Open Access Journals (Sweden)

    Henry E.

    2015-01-01

    Full Text Available The CHIMERA multi-detector array at LNS Catania has been used to study the inverse-kinematics reaction of 78Kr + 40Ca at a bombarding energy of 10 A MeV. Analysis of the experimental data focused on a class of selected events consistent with the complete fusion and subsequent binary split of the of the reacting system. This class of events features a broad A, Z distribution of fission fragments centered about symmetric fission while exhibiting relative velocities significantly higher than given by Viola systematics. The center-of-mass angular distribution (dσ/dΘ of the fission fragments exhibit an unexpected anisotropy inconsistent with a compound-nucleus reaction and indicates a dynamic fusion-fission like process. The observed angular distribution features an asymmetric forward-backward peaking most prevalent for mass-asymmetric events. Furthermore, the more massive fragment of mass-asymmetric events appears to emerge preferentially in the forward direction, along the beam axis, in analogy to dynamic fragmentation of projectile-like fragments. Analysis of the angular distribution of alpha particles emitted from these fission fragments suggests the events are associated mostly with central collisions.

  13. Maine: 2002 Economic Census. Educational Services, Geographic Area Series. EC02-61A-ME.

    Science.gov (United States)

    US Department of Commerce, 2005

    2005-01-01

    The economic census is the major source of facts about the structure and functioning of the nation's economy. It provides essential information for government, business, industry, and the general public. Title 13 of the United States Code (Sections 131, 191, and 224) directs the Census Bureau to take the economic census every 5 years, covering…

  14. SMEX02 Soil Climate Analysis Network (SCAN) Station 2031, Ames, Iowa

    Data.gov (United States)

    National Aeronautics and Space Administration — This work is part of the Soil Moisture Experiment (SMEX) project. This data set provides data from various sensors on the Soil Climate Analysis Network (SCAN)...

  15. Retrospective of photography at NASA Ames Research Center from 1940 to 1996 (Extended Abstract)

    Science.gov (United States)

    Ponseggi, Bernard G.

    1997-05-01

    This paper deals with what is known as photo/optical instrumentation technology and/or technical photography. In 1940 this was called photography, in the late 40's the Civil Service Commission introduced a new classification called photography/technical to differentiate between still photographers and those engaging in recording engineering data. In October of 1958 a historic event took place, Congress transferred all of the duties of NACA to a newly formed agency called NASA, and with it came a call for systems that would keep up with new requirements. There was a need to change the type and style of equipment to keep up with the demands for more accurate information. Existing hardware was modified and new hardware was developed and designed to meet the new requirements of space travel of manned and unmanned orbital vehicles. This family of equipment had to withstand the rigors of space travel such as extremely high `G' forces, temperature changes and `O' gravity, while on earth we needed equipment to document launch of space vehicles as well as wind tunnel testing, rocket sled stands etc.. Some requirements were similar to those of launch vehicles, some were totally different and had other requirements, eventually they were all resolved. As electronic data systems became available NASA experimented with their use in data acquisition. This portion of this session will discuss the changes over the years and their effect on the acquisition of data, those that worked, as well as those that were a disappointment.

  16. Curriculum development for the workplace using Entrustable Professional Activities (EPAs): AMEE Guide No. 99.

    Science.gov (United States)

    Ten Cate, Olle; Chen, Huiju Carrie; Hoff, Reinier G; Peters, Harm; Bok, Harold; van der Schaaf, Marieke

    2015-01-01

    This Guide was written to support educators interested in building a competency-based workplace curriculum. It aims to provide an up-to-date overview of the literature on Entrustable Professional Activities (EPAs), supplemented with suggestions for practical application to curriculum construction, assessment and educational technology. The Guide first introduces concepts and definitions related to EPAs and then guidance for their identification, elaboration and validation, while clarifying common misunderstandings about EPAs. A matrix-mapping approach of combining EPAs with competencies is discussed, and related to existing concepts such as competency milestones. A specific section is devoted to entrustment decision-making as an inextricable part of working with EPAs. In using EPAs, assessment in the workplace is translated to entrustment decision-making for designated levels of permitted autonomy, ranging from acting under full supervision to providing supervision to a junior learner. A final section is devoted to the use of technology, including mobile devices and electronic portfolios to support feedback to trainees about their progress and to support entrustment decision-making by programme directors or clinical teams.

  17. Situativity theory: a perspective on how participants and the environment can interact: AMEE Guide no. 52.

    Science.gov (United States)

    Durning, Steven J; Artino, Anthony R

    2011-01-01

    Situativity theory refers to theoretical frameworks which argue that knowledge, thinking, and learning are situated (or located) in experience. The importance of context to these theories is paramount, including the unique contribution of the environment to knowledge, thinking, and learning; indeed, they argue that knowledge, thinking, and learning cannot be separated from (they are dependent upon) context. Situativity theory includes situated cognition, situated learning, ecological psychology, and distributed cognition. In this Guide, we first outline key tenets of situativity theory and then compare situativity theory to information processing theory; we suspect that the reader may be quite familiar with the latter, which has prevailed in medical education research. Contrasting situativity theory with information processing theory also serves to highlight some unique potential contributions of situativity theory to work in medical education. Further, we discuss each of these situativity theories and then relate the theories to the clinical context. Examples and illustrations for each of the theories are used throughout. We will conclude with some potential considerations for future exploration. Some implications of situativity theory include: a new way of approaching knowledge and how experience and the environment impact knowledge, thinking, and learning; recognizing that the situativity framework can be a useful tool to "diagnose" the teaching or clinical event; the notion that increasing individual responsibility and participation in a community (i.e., increasing "belonging") is essential to learning; understanding that the teaching and clinical environment can be complex (i.e., non-linear and multi-level); recognizing that explicit attention to how participants in a group interact with each other (not only with the teacher) and how the associated learning artifacts, such as computers, can meaningfully impact learning.

  18. Calibration of the Ames Anechoic Facility. Phase 1: Short range plan

    Science.gov (United States)

    Hickey, D.; Soderman, P. T.; Karamcheti, K.; Koutsoyannis, S. P.; Hopkins, R.; Mclachlan, B.

    1980-01-01

    A calibration was made of the acoustic and aerodynamic characteristics of a small, open-jet wind tunnel in an anechoic room. The jet nozzle was 102 mm diameter and was operated subsonically. The anechoic-room dimensions were 7.6 m by 5.5 m by 3.4 m high (wedge tip to wedge tip). Noise contours in the chamber were determined by various jet speeds and exhaust collector positions. The optimum nozzle/collector separation from an acoustic standpoint was 2.1 m. Jet velocity profiles and turbulence levels were measured using pressure probes and hot wires. The jet was found to be symmetric, with no unusual characteristics. The turbulence measurements were hampered by oil mist contamination of the airflow.

  19. Ames Culture Chamber System: Enabling Model Organism Research Aboard the international Space Station

    Science.gov (United States)

    Steele, Marianne

    2014-01-01

    Understanding the genetic, physiological, and behavioral effects of spaceflight on living organisms and elucidating the molecular mechanisms that underlie these effects are high priorities for NASA. Certain organisms, known as model organisms, are widely studied to help researchers better understand how all biological systems function. Small model organisms such as nem-atodes, slime mold, bacteria, green algae, yeast, and moss can be used to study the effects of micro- and reduced gravity at both the cellular and systems level over multiple generations. Many model organisms have sequenced genomes and published data sets on their transcriptomes and proteomes that enable scientific investigations of the molecular mechanisms underlying the adaptations of these organisms to space flight.

  20. Quality assurance software inspections at NASA Ames: Metrics for feedback and modification

    Science.gov (United States)

    Wenneson, G.

    1985-01-01

    Software inspections are a set of formal technical review procedures held at selected key points during software development in order to find defects in software documents--is described in terms of history, participants, tools, procedures, statistics, and database analysis.

  1. Assessing Mutagenicity of Methanolic Exteract of Borage Flower (Echium amuenum Using Ames Bioassay

    Directory of Open Access Journals (Sweden)

    Meysam Moosavi

    2014-08-01

    Full Text Available Background: pyrrolizidine alkaloids have been isolated from Echium amuenum. These alkaloids knowing as hepatotoxic, damage the liver. Mutagenicity of pure pyrrolizidine alkaloids has been identified. Thus, the mutagenic effect of the methanolic flower extract was tested using Amest test. Materials and Methods: The long maceration process (for 48 hrs is carried out in order to extract all constitutes. Thin layer chromatography (TLC method was used to evaluate aflatoxin B1 contamination and histidine amino acid presence. Minimum inhibitory concentration (MIC was determined with the dilution method. Salmonella typhimurium strain TA100 was used to determination of mutagenicity. The genotype was confirmed by using histidine requirement, R- factor presence, rfa and uvrB mutations tests. The mutagenicity assay was performed by four extract concentrations (0.25, 0.5, 0.75 and 1mg/ml. Sodium azide (NaN3 and methanol were used as the mutagens (positive control and negative control, respectively in the absence or presence of liver-metabolizing enzymes. Results: The data indicate that Echium amuenum has not significant mutagenic activity against negative control. The presence of liver-metabolizing enzymes did not exhibit a significant change against the properties of extract. Conclusion: It seems that this extensive used plant in traditional medicine, doesn’t contain mutagenic or genotoxic effect in usual doses.

  2. Aligning physical learning spaces with the curriculum: AMEE Guide No. 107.

    Science.gov (United States)

    Nordquist, Jonas; Sundberg, Kristina; Laing, Andrew

    2016-08-01

    This Guide explores emerging issues on the alignment of learning spaces with the changing curriculum in medical education. As technology and new teaching methods have altered the nature of learning in medical education, it is necessary to re-think how physical learning spaces are aligned with the curriculum. The better alignment of learning spaces with the curriculum depends on more directly engaged leadership from faculty and the community of medical education for briefing the requirements for the design of all kinds of learning spaces. However, there is a lack of precedent and well-established processes as to how new kinds of learning spaces should be programmed. Such programmes are essential aspects of optimizing the intended experience of the curriculum. Faculty and the learning community need better tools and instruments to support their leadership role in briefing and programming. A Guide to critical concepts for exploring the alignment of curriculum and learning spaces is provided. The idea of a networked learning landscape is introduced as a way of assessing and evaluating the alignment of physical spaces to the emerging curriculum. The concept is used to explore how technology has widened the range of spaces and places in which learning happens as well as enabling new styles of learning. The networked learning landscaped is explored through four different scales within which learning is accommodated: the classroom, the building, the campus, and the city. High-level guidance on the process of briefing for the networked learning landscape is provided, to take into account the wider scale of learning spaces and the impact of technology. Key to a successful measurement process is argued to be the involvement of relevant academic stakeholders who can identify the strategic direction and purpose for the design of the learning environments in relation to the emerging demands of the curriculum.

  3. Self-regulation theory: applications to medical education: AMEE Guide No. 58.

    Science.gov (United States)

    Sandars, John; Cleary, Timothy J

    2011-01-01

    Self-regulation theory, as applied to medical education, describes the cyclical control of academic and clinical performance through several key processes that include goal-directed behaviour, use of specific strategies to attain goals, and the adaptation and modification to behaviours or strategies to optimise learning and performance. Extensive research across a variety of non-medical disciplines has highlighted differences in key self-regulation processes between high- and low-achieving learners and performers. Structured identification of key self-regulation processes can be used to develop specific remediation approaches that can improve performance in academic and complex psycho-motor skills. General teaching approaches that are guided by a self-regulation perspective can also enhance academic performance. Self-regulation theory offers an exciting potential for improving academic and clinical performance in medical education.

  4. Report on the 2011 and 2012 NASA Ames Research Center (ARC) / Alaska State Cargo Airship Workshops

    Science.gov (United States)

    Hochstettler, Ronald

    2012-01-01

    This presentation will summarize the Cargo Airships for Northern Operations workshop that was held August 24-25, 2011. This workshop co-sponsored by NASA ARC and the Alaska State Department of Transportation was initiated by interest from Alaska Lt. Governor Mead Treadwell for assistance in investigating the potential benefits of proposed cargo airships for the Alaskan economy and societal needs. The workshop provided a brief background on the technology and operational aspects of conventional airships and hybrids followed by presentations on issues affecting cargo airship operations such as weather management, insurance, regulations, crew duty/rest rules, and available support infrastructures. Speakers representing potential cargo airship users from Alaskan State and commercial organizations presented the needs they felt could be met by cargo airship services. Presenters from Canadian private and military interests also detailed applications and missions that cargo airships could provide to remote regions of Canada. Cost drivers of cargo airship operations were also addressed and tools for modeling and analyzing operational factors and costs affecting cargo airship operations were discussed. Four breakout sessions were held which allowed workshop participants to contribute inputs to four topic areas: Business Approaches and Strategies (financing incentives public/private partnerships etc) for Airship Development and Operation, Design, Development, Production Challenges, and Possible Solutions, Regulatory, Certification, Legal, and Insurance Issues, and Operational Issues, Customer Requirements, and Airship Requirements. A follow on to the 2011 cargo airship workshop is being planned for July 31 August 2, 2012. A status update on this second workshop will also be presented.

  5. Ryanair lubab tuua 300 000 turisti ja 300 uut töökohta / Teele Tammeorg, Dannar Leitmaa

    Index Scriptorium Estoniae

    Tammeorg, Teele

    2010-01-01

    Odavlennufirma Ryanair teeb esimesed otselennud Tallinnast 13. detsembril, lennuühendus luuakse seitsme Euroopa linnaga. Riiast lendavad Ryanairi lennukid 44 sihtkohta. Keskmine lennupileti hind on 35 eurot

  6. SEB analüütik Ruta Arumäe: Eesti valitsus teeb majanduskriisiga võideldes Lätile ja Leedule silmad ette / Ruta Arumäe ; intervjueerinud Andres Reimer

    Index Scriptorium Estoniae

    Arumäe, Ruta, 1976-

    2009-01-01

    SEB analüütiku hinnangul jätkub majanduse langus järgmise aasta lõpuni, kuid see toimub senisest aeglasemalt; töötus võib kasvada selle aasta lõpuks 14 protsendini. Taastumine saab alata ekspordile suunatud majandusharudest, uus majanduskasv saab alguse välisnõudluse taastumisest

  7. Krajeugolnõi kamen budjet zalozhen v maje / Eteri Kekelidze

    Index Scriptorium Estoniae

    Kekelidze, Eteri, 1944-

    2005-01-01

    Tallinna Vene Draamateatri hoone remondist. Remonditöid teeb Facio Ehituse AS. Lammutatakse hoone tagumine osa ja ehitatakse uus kuuekorruseline hooneosa, kuhu tulevad lava, Blak box, garderoob ja baar. Uue lava projekti teeb selle ala ainus spetsialist Eestis Maldar Mikk-Kuusk

  8. Estonia purjetab filmiturule / Jüri Laulik

    Index Scriptorium Estoniae

    Laulik, Jüri, 1959-

    2003-01-01

    Saksamaal Berliinis esilinastub pidulikult 13. oktoobril poliitiline põnevusfilm "Balti torm" ("Baltic Storm"), mis kujutab parvlaev "Estonia" hukku. Režissöör ja üks stsenariste on Reuben Leder, peaosades Greta Scacchi ja Jürgen Prochnow. Kaasa teeb ka Donald Sutherland USA kindrali rollis. Eesti näitlejaist teeb kaasa Rein Oja

  9. Governing ecosystem services

    NARCIS (Netherlands)

    Verburg, René; Selnes, Trond; Verweij, Pita

    2016-01-01

    The TEEB approach to the use of ecosystem services has found its way to policy as a means to biodiversity conservation and greening of the economy. In this paper we analysed the uptake of the TEEB approach at national and local levels by applying a framework that revolves around the problem,

  10. law, the laws of nature and ecosystem energy services

    African Journals Online (AJOL)

    Office 2004 Test Drive User

    See UNEP TEEB Mainstreaming the Economics of Nature 34. TEEB is hosted by the. United Nations Environment Programme and supported by the European Commission, the. German Federal Ministry for the Environment, Nature Conservation and Nuclear Safety, the UK government's Department for the Environment, ...

  11. Aging material evaluation and studies by non-destructive techniques (AMES-NDT) - a European network project

    International Nuclear Information System (INIS)

    Dobmann, Gerd; Debarberis, Luigi; Coste, Jean-Francois

    2001-01-01

    This paper presents results obtained in a round-robin action organized in a concerted action of ten partners in the EURATOM program of the European Community. The objective of the research was to document the state of the art of available non-destructive testing (NDT) techniques in order to characterize material aging phenomena based on a reduction of Charpy-V energy and a shift in the fracture appearance transition temperature. Therefore, samples from the Japanese nuclear reactor pressure vessel JRQ-steel (ASMT Standard A533-B Class 1) have been thermally treated at 700 deg. C for 18 h with a subsequent water quenching. Besides micromagnetic and electromagnetic NDT, the positron annihilation technique, ultrasonic reverberation by using Laser ultrasonics and the thermo-electrical power have been applied to characterize the aged material states

  12. Huellas de las religiones tradicionales del áfrica subsahariana en américa latina y el caribe

    OpenAIRE

    Cabrera Thompson, Lazaro

    2010-01-01

    El artículo explora las religiones tradicionales practicadas por los pueblos ewe-mina, ewe-fon, bantú y yoruba del África subsahariana, antes de abordar las formas como estas prácticas religiosas persisten en el “Nuevo Mundo” tras la llegada forzosa de aquellos esclavizados africanos. Con base en la presencia de estas religiones tradicionales africanas en distintos países latinoamericanos y caribeño, se evidencia un conjunto religioso fusionado por historias, mitos, leyendas, danza, mú...

  13. The Objective Structured Clinical Examination (OSCE): AMEE Guide No. 81. Part I: an historical and theoretical perspective.

    Science.gov (United States)

    Khan, Kamran Z; Ramachandran, Sankaranarayanan; Gaunt, Kathryn; Pushkar, Piyush

    2013-09-01

    The Objective Structured Clinical Examination (OSCE) was first described by Harden in 1975 as an alternative to the existing methods of assessing clinical performance (Harden et al. 1975). The OSCE was designed to improve the validity and reliability of assessment of performance, which was previously assessed using the long case and short case examinations. Since then the use of the OSCE has become widespread within both undergraduate and postgraduate clinical education. We recognise that the introduction of the OSCE into an existing assessment programme is a challenging process requiring a considerable amount of theoretical and practical knowledge. The two parts of this Guide are designed to assist all those who intend implementing the OSCE into their assessment systems. Part I addresses the theoretical aspects of the OSCE, exploring its historical development, its place within the range of assessment tools and its core applications. Part II offers more practical information on the process of implementing an OSCE, including guidance on developing OSCE stations, choosing scoring rubrics, training examiners and standardised patients and managing quality assurance processes. Together we hope these two parts will act as a useful resource both for those choosing to implement the OSCE for the first time and also those wishing to quality assure their existing OSCE programme.

  14. Development of a High Resolution Weather Forecast Model for Mesoamerica Using the NASA Ames Code I Private Cloud Computing Environment

    Science.gov (United States)

    Molthan, Andrew; Case, Jonathan; Venner, Jason; Moreno-Madrinan, Max J.; Delgado, Francisco

    2012-01-01

    Two projects at NASA Marshall Space Flight Center have collaborated to develop a high resolution weather forecast model for Mesoamerica: The NASA Short-term Prediction Research and Transition (SPoRT) Center, which integrates unique NASA satellite and weather forecast modeling capabilities into the operational weather forecasting community. NASA's SERVIR Program, which integrates satellite observations, ground-based data, and forecast models to improve disaster response in Central America, the Caribbean, Africa, and the Himalayas.

  15. Ames Infusion Stories for NASA Annual Technology Report: Nano Entry System for CubeSat-Class Payloads

    Science.gov (United States)

    Smith, Brandon; Jan, Darrell Leslie; Venkatapathy, Etiraj

    2015-01-01

    The Nano Entry System for CubeSat-Class Payloads led to the development of the Nano-Adaptable Deployable Entry and Placement Technology ("Nano-ADEPT"). Nano-ADEPT is a mechanically deployed entry, descent, and landing (EDL) system that stows during launch and cruise (like an umbrella) and serves as both heat shield and primary structure during EDL. It is especially designed for small spacecraft where volume is a limiting constraint.

  16. 2010 Review on the Extension of the AMedP-8(C) Methodology to New Agents, Materials, and Conditions

    Science.gov (United States)

    2010-12-01

    primary thermal injuries (flash burns) from the thermal pulse from a nuclear detonation; • Acute injuries from exposures to three chemical agents (sarin...OTSG 11 . S P O N S OR ’S / M O N I TOR ’S R E P OR T N O (S ) . 1 2 . D IS T R I B U T IO N / AVA I L A B I L I T Y S TATE M E N T

  17. Evaluation of Physostigmine Salicylate Using a High Concentration of Liver S-9 Fraction in the Ames Test for Mutagenicity

    Science.gov (United States)

    1989-07-01

    Mammalian Microsome Mutagenicity Test. iii ACKNOWLEDGMENTS SGT Lillie D. Witcher , BS, USA, SGT Gayle Orner, BS, USA, and SPC Joel Seewald, BS, USA...Physostigmine Salicylate, Final Report; MBA, Rockville MD; 3 December 1987; Study number T5728.701. 4. Harbell JW, Witcher LD, Korte DW. Sister

  18. Proceedings of the FAA Inspection Program Area Review, Held in Ames, Iowa on April 5-7, 1994

    Science.gov (United States)

    1994-07-01

    Corrosion Inspection Technology: 13:20 Thermal Wave Imaging R. Thomas, WSU 14:05 Dual Band Infrared Imaging N. DelGrande, LLNL 14:25 Ultrasonic...Palmer, Scott Northwest Airlines (612) 452 7803 Papadakis, Emmanuel CASR Iowa State University (515) 294 9738 Patton , Thadd CASR Iowa State University...8217............... ....... I. . . .. .. . matri. loss 1 . ". ... . . . . l . .... .... . .. .. I • I • i, " ,,.~ ~~ ~~ .... .. . , - t rl ll s z 0 Woo I-l900 00 E 4w Sa) 0 222 x

  19. Performance results from a test of an S-76 rotor in the NASA Ames 80- by 120-foot wind tunnel

    Science.gov (United States)

    Shinoda, Patrick M.; Johnson, Wayne

    1993-01-01

    A full-scale helicopter rotor wind tunnel test has been conducted which covers a wide range of rotor-shaft angles-of-attack and 0-100 kt thrust conditions. The hover performance data thus obtained were compared with the results of momentum theory calculations; forward flight rotor-performance data were compared with calculations from a comprehensive rotorcraft analysis. These comparisons suggest that hover testing at an outdoor facility in the absence of ground effect is required to make a final determination of the absolute accuracy of the wind tunnel hover data.

  20. Genotoxicity investigation of araticum(Annona crassiflora Mart., 1841, Annonaceae using SOS-Inductest and Ames test

    Directory of Open Access Journals (Sweden)

    JB. Vilar

    Full Text Available Although the use of medicinal plants or natural products has increased in recent decades all over the world, little information is available on their potential risk to health. Annona crassiflora Mart., a plant commonly known as araticum in Brazil, has been widely used in folk medicine for a long time since its seeds and leaves are often utilised in the treatment of cancer, snake bites, and venereal diseases, its fruits are consumed as tonic and astringent, and its bark powder has anti-fungal and anti-rheumatic properties. To evaluate the genotoxic and mutagenic properties induced by the ethanolic extract of araticum leaves, we performed the prophage λ induction (Inductest and bacterial mutagenicity assays. We used Escherichia coli WP2s(λ and RJF013 strains in the lysogenic induction test, whereas the mutagenic studies were carried out using Salmonella typhimurium histidine auxotroph strains TA97a, TA98, TA100, and TA102. Each experiment was performed three times in duplicate and included positive and negative controls. No statistically significant (p > 0.05 positive results were obtained for any of the strains tested, which suggests that the ethanolic extract of araticum leaves did not exhibit direct mechanisms of genotoxicity or mutagenicity that could be detected by the tests used in the present work.

  1. Possible Mechanisms of Ternary Fission in the 197Au+197 Au System at 15 AMeV

    International Nuclear Information System (INIS)

    Jun-Long, Tian; Xian, Li; Shi-Wei, Yan; Xi-Zhen, Wu; Zhu-Xia, Li

    2009-01-01

    Ternary fission in 197 Au+ 197 Au collisions at 15 A MeV is investigated by using the improved quantum molecular dynamical (ImQMD) model. The experimental mass distributions for each of the three fragments are reproduced for the first time without any freely adjusting parameters. The mechanisms of ternary fission in central and semi-central collisions are dynamically studied. In direct prolate ternary fission, two necks are found to be formed almost simultaneously and rupture sequentially in a very short time interval. Direct oblate ternary fission is a very rare fission event, in which three necks are formed and rupture simultaneously, forming three equally sized fragments along space-symmetric directions in the reaction plane. In sequential ternary fission a binary division is followed by another binary fission event after hundreds of fm/c. (nuclear physics)

  2. Atmospheric Methane Measurements from an Aircraft Based at NASA Ames: Five Years of Observations by the AJAX Project

    Science.gov (United States)

    Iraci, Laura

    2016-01-01

    The Alpha Jet Atmospheric eXperiment (AJAX) is a research project based at Moffett Field, CA, which collects airborne measurements of ozone, carbon dioxide, methane, water vapor, and formaldehyde, as well as 3-D winds, temperature, pressure, and location. Since its first science flight in 2011, AJAX has developed a wide a variety of mission types, combining vertical profiles (from approx. 8 km to near surface),boundary layer legs, and plume sampling as needed. With an ongoing five-year data set, the team has sampled over 160 vertical profiles, a dozen wildfires, and numerous stratospheric ozone intrusions. This talk will present an overview of our flights flown to date, with particular focus on methane observations in the San Francisco Bay Area, Sacramento, and the delta region.

  3. Au+Au central collisions at 150, 250 and 400 AMeV energies in QMD with relativistic forces

    OpenAIRE

    Nemeth, J.; Papp, G.; Feldmeier, H.

    1998-01-01

    An extensive comparison of the recent experimental data published by the FOPI collaboration at GSI with the results of a relativistically covariant formulation of a QMD code is presented. For most of the quantities we find agreement with the experimental results showing that the derived force has a reasonable momentum dependence.

  4. 2012 Review on the Extension of the AMedP-8(C) Methodology to New Agents, Materials, and Conditions

    Science.gov (United States)

    2013-10-01

    developing human response modeling parameters for five new chemical agents (chlorine, cyanogen chloride, hydrogen cyanide , hydrogen sulfide, and phosgene... poisoning , can result in toxic shock syndrome when delivered through a nonenteric route.165 Approximately 75 cases of staphylococcal toxic-shock syndrome...the 2012 episode, none of the potentially exposed individuals developed symptoms of mustard poisoning .263 In addition to these more recent

  5. Real time computer data system for the 40 x 80 ft wind tunnel facility at Ames Research Center

    Science.gov (United States)

    Cambra, J. M.; Tolari, G. P.

    1974-01-01

    The wind tunnel realtime computer system is a distributed data gathering system that features a master computer subsystem, a high speed data gathering subsystem, a quick look dynamic analysis and vibration control subsystem, an analog recording back-up subsystem, a pulse code modulation (PCM) on-board subsystem, a communications subsystem, and a transducer excitation and calibration subsystem. The subsystems are married to the master computer through an executive software system and standard hardware and FORTRAN software interfaces. The executive software system has four basic software routines. These are the playback, setup, record, and monitor routines. The standard hardware interfaces along with the software interfaces provide the system with the capability of adapting to new environments.

  6. Subsonic Wake Characterization of the Orion Capsule Using PIV in the Ames UPWT 11-foot Wind Tunnel (Invited)

    Science.gov (United States)

    Heineck, James T.; Ross, James C.; Yamauchi, Gloria K.

    2015-01-01

    The subsonic regime of Crew Capsule reentry has a very turbulent waker through which the Drogue Chutes must deploy. This presentation describes the particle image velocimetry measurement campaign used to help retire the risk.

  7. Housing differences in the late soviet city : the case of Tartu, Estonia / Hill Kulu

    Index Scriptorium Estoniae

    Kulu, Hill

    2003-01-01

    Autor teeb 1989. aasta rahvaloenduse andmetele tuginedes ülevaate Tartu elanikkonna eluasemete omandivormidest, elamistingimuste erinevustest ning seda mõjutavatest teguritest nõukogude perioodi lõpul. Diagrammid ja tabelid

  8. Salamander võib õpetada jäsemete kasvatamist / Tiit Kändler

    Index Scriptorium Estoniae

    Kändler, Tiit, 1948-

    2008-01-01

    Salamander on selgroogsete seas ainulaadne olevus. Ta suudab endale kasvatada ka täiskasvanuna uued kehaosad. Kui arstiteadlased välja uurivad, kuidas ta seda teeb, võib see aidata ka inimest rasketest haavadest ravida

  9. Web aitab nutikamaid firmasid / Peeter Stamberg

    Index Scriptorium Estoniae

    Stamberg, Peeter

    2003-01-01

    Interneti-lahendustesse investeerimine on aidanud paljudel ettevõtetel oma tulemusi parandada. Autor teeb ülevaate ajakirjas BusinessWeek avaldatud edukamatest internetiprojektidest. Lisa: Internetiäri teine laine

  10. AstraZeneca lõpetab kingitused. Karmim kord

    Index Scriptorium Estoniae

    2011-01-01

    Ravimifirma AstraZeneca teeb lõpu arstide kinnimakstud koolitusreisidele ja teistele hüvedele, jõudes seisukohale, et ainus põhjus ravimi väljakirjutamiseks on ravim ise. Suurbritannia ja Saksamaa korruptsioonivastasest regulatsioonist

  11. Assa Evolution - novoje pokolenije zamkov / Maigi Peeduli

    Index Scriptorium Estoniae

    Peeduli, Maigi

    2003-01-01

    Rootsi lukufirma Assa AB tootearendus põhineb moodulsüsteemil, mis teeb elu mugavaks arhitektidel, ehitajatel ja lukukasutajatel, kuna see võimaldab lukuraame komplekteerida erinevate südamike, linkide ja katetega

  12. Assa Evolution - lukustuse uus põlvkond / Maigi Peeduli

    Index Scriptorium Estoniae

    Peeduli, Maigi

    2003-01-01

    Rootsi lukufirma Assa AB tootearendus põhineb moodulsüsteemil, mis teeb elu mugavaks arhitektidel, ehitajatel ja lukukasutajatel, kuna see võimaldab lukuraame komplekteerida erinevate südamike, linkide ja katetega

  13. Kas Karel Rüütli tegi Pavlik Morozovit / Peeter Ernits

    Index Scriptorium Estoniae

    Ernits, Peeter, 1953-

    2010-01-01

    Pingetest Eestimaa Rahvaliidus. Rahvaliidu võimalikust ühinemisest Sotsiaaldemokraatliku Erakonnaga. Lõpliku otsuse, kas ühineda sotsiaaldemokraatidega või jätkata iseseisvana, teeb erakonna kongress 23. mail

  14. Mis meil Aasiast? / Marianne Mikko

    Index Scriptorium Estoniae

    Mikko, Marianne, 1961-

    2008-01-01

    Ilmunud ka: Severnoje Poberezhje 6. august lk. 2, Põhjarannik, Koit 7. august lk. 2,6. Europarlamendiliige teeb ülevaate oma visiidist Hiinasse ja Kambodzhasse, eesmärgiga koguda infot Tiibetis toimuvast

  15. Birma hunta jätkab repressioone / Igor Taro

    Index Scriptorium Estoniae

    Taro, Igor

    2007-01-01

    Amnesty International teatas, et Birma diktaatorlikud võimud jätkavad teisitimõtlejate vahistamist, samal ajal teeb ÜRO saadik Ibrahim Gambari huntale poliitilise surve avaldamiseks ringsõitu Kagu-Aasias. Lisa: Rahutu riik Birma

  16. Vaikne Don : [luuletused] / Mart Kangur

    Index Scriptorium Estoniae

    Kangur, Mart

    2004-01-01

    Sisu: Vaikne Don ; "Imelik, kui kerge on hakata armastama neid ..." ; "Laud otsekui tool ..." ; "Raamat on monument ..." ; "Nägu on liiga tühi ..." ; "Mida teeb Buddha pärast virgumist? Peseb hambaid ..."

  17. Keera korter päikesesse / Tanel Veenre

    Index Scriptorium Estoniae

    Veenre, Tanel, 1977-

    2009-01-01

    Itaalia arhitekti David Fisheri pöörleva pilvelõhkuja projektist. 80-korruseline moodulitest ökoelamu peaks valmina Dubais 2010. a. Iga korrus liigub teistest sõltumatult ja teeb 360-kraadise tiiru ühe tunniga

  18. Res Publica asus Reformierakonda Tallinna võimuliidust tõrjuma / Mirko Ojakivi

    Index Scriptorium Estoniae

    Ojakivi, Mirko

    2005-01-01

    Res Publica Tallinna piirkonna juhatuse liikme Siim Roode sõnul teeb Res Publica Keskerakonna Tallinna piirkonna juhatusele ettepaneku koalitsiooniläbirääkimiste alustamiseks. Lisa: Paltsu ettekäändeks Unicom

  19. Börsilt ei tule kunagi lihtsalt raha / Gary Weissi ; interv. Neeme Raud

    Index Scriptorium Estoniae

    Weissi, Gary

    2003-01-01

    Intervjuu ajakirja Business Week vanemkorrespondendi ja raamatu "Born To Steal" autori Gary Weissiga aktsiapettustest ja organiseeritud kuritegevuse seostest börsidega. Autor teeb lühikokkuvõtte oma raamatust

  20. Moeteateid Pariisist / Urmas Väljaots

    Index Scriptorium Estoniae

    Väljaots, Urmas, 1981-

    2008-01-01

    Pariisi moemaja Chloe. Belgia moekunstnik Maison Martin Margiela. Parfüümireklaamides kasutatakse kuulsaid filminäitlejaid. Kiirmoekett H & M teeb koostööd kuulsate disaineritega. Pariisi tänavamood

  1. Jätkub filmisari "Ainult friikidele"

    Index Scriptorium Estoniae

    2008-01-01

    Filmisarjas "Ainult friikidele" linastub Tallinnas Sõpruse kinos täna ja Tartus Athena Keskuses homme Alain Corneau' kutuslik kriminaalfilm "Serie noir" : Prantsusmaa 1979. Suurepärase rolli teeb Patrick Dewaere

  2. Baltoscandal kingib linlastele etenduse / Aarne Mäe

    Index Scriptorium Estoniae

    Mäe, Aarne, 1967-

    2002-01-01

    Rahvusvaheline teatrifestival Baltoscandal teeb ühe etendusega kingituse linnarahvale : 14. juunil näidatakse Rakvere Teatris Battery Dance Company programmi "Used Car Salesman", "Mother Goose", "Layapriya", "The anyones ballet", lavastaja ja koreograaf Jonathan Hollander

  3. Bushi uusim prohmakas / George Soros

    Index Scriptorium Estoniae

    Soros, George, 1930-

    2007-01-01

    Ilmunud ka: Postimees : na russkom jazõke 20. märts lk. 7. Autor on seisukohal, et USA teeb vea Lähis-Ida poliitikas, toetades Iisraeli valitsust, kes ei tunnusta Palestiina koalitsioonivalitsust Hamasi osavõtul

  4. Kes siirdab esimesena näo? / Aadu Hiietamm

    Index Scriptorium Estoniae

    Hiietamm, Aadu, 1954-

    2004-01-01

    Prantsuse kirurg Laurent Lantieri teeb ettevalmistusi surnud inimese näo siirdamiseks tugevasti moonutatud näoga patsiendile. Analoogiliseks operatsiooniks valmistuvad ka inglane Peter Butler ja ameeriklane John Barker

  5. Tippdisain Hank Vu'lt Urbana teostuses

    Index Scriptorium Estoniae

    1999-01-01

    Vietnamis sündinud, Ameerika Ühendriikides Kalifornias töötav arhitektiharidusega mööblidisainer Hank Vu teeb lihtsat, funktsionaalset, abstraktselt orgaanilise vormiga mööblit. 6 illustratsiooni

  6. Linnateater pöördub Luigi Pirandello poeesia juurde / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2006-01-01

    Adolf Shapiro hakkab Linnateatris lavastama Luigi Pirandello "Nii see on, kui teile nii näib", kunstnikutöö teeb Vladimir Anshon, kostüümid Kristina Pasternaka Lätist ja valguskunstnik on Gleb Felshtinski

  7. Sõnnikust elektri tootmine on Eesti Energia otsustada / Toivo Tänavsuu

    Index Scriptorium Estoniae

    Tänavsuu, Toivo

    2006-01-01

    Seakasvatusfirma Ekseko tahab hakata seasõnnikust elektrit ja soojust tootma, kui Eesti Energia finantseerib projekti. Taani konsultatsioonifirma Energy Consulting Network soovitab rajada koostootmisjaama maksumusega umbes 50-60 miljonit krooni. Lisa: Eesti Energia teeb otsuse lähiajal

  8. Kunstnikud loovad maapinnal ja õhus / Aivi Pargi

    Index Scriptorium Estoniae

    Pargi, Aivi, 1950-

    2001-01-01

    Kunstirühmituse The Circle (Anne Kokkov, Maris Kärdi) korraldatavast maakunstisümpoosionist Rakveres, mille käigus teeb õhuskulptuuri rootsi kunstnik Hans Tjörneryd ja tuleskulptuure Anne Kokkov

  9. Saaremaa maaelu ja põllumajandus said mullu ligi 140 miljonit toetust / Ain Lember

    Index Scriptorium Estoniae

    Lember, Ain

    2005-01-01

    Saare maakond sai 2004. aastal enam kui 138 miljoni krooni eest maaelu- ja põllumajandustoetusi, mis teeb iga maal elava inimese kohta 6760 krooni. Tabelid: Toetussumma maakonna lõikes; Toetussumma iga maal elava inimese kohta (kroonides)

  10. Puiduettevõte jätab Soomes töötuks üle tuhande inimese

    Index Scriptorium Estoniae

    2007-01-01

    Rahvusvaheline metsanduskontsern Stora Enso, kes omab ettevõtteid ka Eestis, suleb masinaid ja terveid vabrikuid Soomes ja Rootsis ning teeb suuri muudatusi juhtkonnas, mistõttu kaotab töö umbes 1400 inimest

  11. Ago Silde : "Olin täiesti ebatüüpiline maavanem" / Ago Silde ; interv. Erik Gamzejev

    Index Scriptorium Estoniae

    Silde, Ago

    2007-01-01

    Ilmunud ka: Severnoje Poberezhje : Subbota, 12. mai 2007, lk. 3. Intervjueeritav teeb tagasivaate oma tööle Ida-Viru maavanemana, ka parlamendivalimistest. Arvamust avaldavad Tõnis Seesmaa ja Urve Erikson

  12. Keskmine pension tõuseb / Heimar Lenk

    Index Scriptorium Estoniae

    Lenk, Heimar, 1946-

    2006-01-01

    Ilmunud ka: Vali Uudised 8. nov. lk. 2, Videvik 16. nov. lk. 2, Elva Postipoiss 18. nov. lk. 4. Autor teeb tagasivaate Eesti pensionipoliitikale ning kinnitab, et pensionid tõusevad 2007. aastal 18% võrra

  13. Letter from Little Lithuania / Michael Tarm

    Index Scriptorium Estoniae

    Tarm, Michael

    2004-01-01

    Autor teeb ülevaate Eesti, Läti, Leedu toodetest ja kaubamärkidest USA turul, Baltimaadesse puutuva kajastamisest USA meedias ning USA avalikkuse teadlikkusest Balti riikidest, sportlastest ja kultuuritegelastest

  14. Keskkonnaministeeriumi allasutuste liitmine vajab spetsialistide hinnangut / Karel Rüütli

    Index Scriptorium Estoniae

    Rüütli, Karel, 1978-

    2008-01-01

    Eestimaa Rahvaliidu fraktsioon esitas valitsusele pöördumise, milles teeb ettepaneku moodustada keskkonnaministeeriumi haldusalas toimuva reformi analüüsimiseks kõiki looduskaitseorganisatsioone ja -teadlasi kaasav valitsuskomisjon

  15. Norma aktsionäridel lootus erakorralisele dividendile / Annika Matson

    Index Scriptorium Estoniae

    Matson, Annika, 1976-

    2004-01-01

    Kolmandas kvartalis paremat kasumlikkust näidanud Norma juhtkond teeb aasta alguses nõukogule ettepaneku maksta erakorralisi dividende. Diagramm: Ettevõtetel olev vaba raha aktsia kohta. Kommenteerib Teet Kolts

  16. Päri Jaak / Villem Reiman

    Index Scriptorium Estoniae

    Reiman, Villem, 1861-1917

    2015-01-01

    27. veebruaril 1671 tõi mõisnik Willibalt von Bärgen oma teenri Jaagu Viljandisse Rootsi kirikukatsumisele - artikkel teeb sellest sündmusest arhiiviandmete (visitatsiooniprotokollide) põhjal kokkuvõtte

  17. The influence of the development potential of China's economy on the logistics of the East and the West / Ho Jianmin = Влияние потенциала развития китайской экономики на логистику Востока �

    Index Scriptorium Estoniae

    Jianmin, Ho

    2003-01-01

    Ettekanne 3.-4. detsembrini 2003 Tallinnas toimunud rahvusvahelisel konverents-näitusel "Logistics and transport in international trade" teeb ülevaate Hiina majanduslikust arengust, väliskaubanduse olukorrast ning arenguprogrammist logistika ja transpordi valdkonnas.Tabelid

  18. BRS pakub raudteed riigile tagasi / Martti Kass

    Index Scriptorium Estoniae

    Kass, Martti

    2005-01-01

    Majandus- ja kommunikatsiooniministeerium moodustab komisjoni, mis analüüsib BRS-i pakkumist ja teeb valitsusele oma ettepaneku. BRS hindab Eesti Raudtee väärtuseks 6 miljardit krooni. Lisa: Dividendid

  19. Laulupeost kaks filmi / Anneli Ammas

    Index Scriptorium Estoniae

    Ammas, Anneli, 1962-

    2004-01-01

    Tänavusest laulu- ja tantsupeost on Allfilmilt tellinud filmi Prantsuse-saksa telekanal ARTE. USA jaoks teeb filmi "Laulev revolutsioon" USA kompanii Mountain View Production eesti päritolu režissöör Jim Dusty

  20. Uudised : ERSO menu Rootsis. Õhtu Metropolitan Operas. NYYD Ensemble'i kontserdid / Madis Kolk

    Index Scriptorium Estoniae

    Kolk, Madis, 1953-

    2001-01-01

    ERSO kontserdireisist Rootsis. "Klassikaraadio" teeb 17. veebr. otseülekande New Yorgi Metropolitan Operast, kus tuleb ettekandele Rossini ooepr "Itaallanna Alzhiiris". NYYD Ensemble'i kontsertidest Pärnus ja Tallinnas kontserdisarjas "I Got Rhythm"

  1. Euroopa Keskpanga rahapoliitika strateegia pärast selle täpsustamist 2003. aasta mais / Jean-Claude Trichet

    Index Scriptorium Estoniae

    Trichet, Jean-Claude, 1942-

    2004-01-01

    Autor teeb ülevaate Euroopa Keskpanga rahapoliitika strateegia ajaloost, strateegia elementidest ning Euroopa ees seisvatest ülesannetest majanduskasvu potentsiaali ja fiskaalpoliitika usaldusväärsuse tõstmiseks

  2. Kohe näha, et valimiste aeg on käes / Villu Reiljan

    Index Scriptorium Estoniae

    Reiljan, Villu, 1953-

    2001-01-01

    ERL esimees kinnitab, et ERL toetab Arnold Rüütli kandidatuuri lõpuni ja teeb kõik selleks, et valijameeste kogu valiks presidendi juba septembris. ERL ja Keskerakonna presidendikandidaatide toetusest. Autor: ERL: Parlamendisaadik

  3. Metalingvistiline teadlikkus võõrkeeleõppes : oma keel võõras peeglis / Annekatrin Kaivapalu

    Index Scriptorium Estoniae

    Kaivapalu, Annekatrin, 1963-

    2010-01-01

    Uuritakse, milliseid tähelepanekuid teeb õppija võõrkeeli õppides oma emakeele, antud juhul eesti ja soome keele kohta ning kas ja millises osas ühtivad õppijate arusaamad keelte lingvistiliste kirjeldustega

  4. Democracy in a bottle : attitudes towards alcohol regulation in the Post-Communist Baltic Sea Region / Therese C. Reitan

    Index Scriptorium Estoniae

    Reitan, Therese C.

    2003-01-01

    Baltimaades ja Poolas läbi viidud uuringust eesmärgiga selgitada välja avalikkuse suhtumine alkoholi, selle kättesaadavusega seotud probleemide reguleerimise kohta. Autor teeb ülevaate uuringu tulemustest. Tabelid. Lisa

  5. Russalka laevahukk jõuab maailma telepilti / Riho Laurisaar

    Index Scriptorium Estoniae

    Laurisaar, Riho

    2005-01-01

    Kanada filmigrupp Eco-Nova Productions Ltd teeb Eesti Meremuuseumi ja Tuukritööde OÜ abiga Soome lahes 1893.a. hukkunud vene sõjalaeva Russalka vrakist dokumentaalfilmi National Geographicu ja Discovery Channeli jaoks

  6. Vjatsheslav Tihhonov stanet bogom / Anna Veligzhanina

    Index Scriptorium Estoniae

    Veligzhanina, Anna

    2006-01-01

    Vene režissöör Eldar Rjazanov teeb oma viimase filmi muinasjutuvestja Hans Christian Anderseni elust. Esialgne pealkiri on "Andersen. Fantazii na temu". Filmist ja näitleja Vjatsheslav Tihhonovi rollist

  7. KGB kunagisest kontorist tehakse noobel korterelamu / Kristjan Pihl

    Index Scriptorium Estoniae

    Pihl, Kristjan

    2011-01-01

    Tallinnas Pagari 1 asuva muinsuskaitsealuse juugendstiilis hoone renoveerimisest korterelamuks. Kavandi teeb AB ARS Projekt. Ajaloolase Robert Nermani sõnul lasi William Tulip selle maja 1912. a. ehitada esialgu kortermajaks

  8. Borisov not packing his bags yet

    Index Scriptorium Estoniae

    2004-01-01

    Leedu kodakondsusest ilma jäetud ärimees Juri Borissov esitas migratsiooniametile taotluse Leedus alalise elamisloa saamiseks. Migratsiooniamet teeb lähipäevil otsuse Borissovi Leetu jäämise lubamise osas

  9. Lapse sünd, abiellumine ja juubel toovad töötajale lisaraha / Kristel Kossar

    Index Scriptorium Estoniae

    Kossar, Kristel

    2005-01-01

    Konsultatsioonifirma Fontes 2004. aasta palgauuringu andmetel teeb 75 protsenti ettevõtetest töötajatele tähtpäevade puhul kingitusi, milleks on tavaliselt rahaline preemia, ilu- või tarbeese. Lisa: Ettevõtted kingivad

  10. Maksuvõlglaste arv kahanes aastaga protsendi võrra

    Index Scriptorium Estoniae

    2004-01-01

    Maksu- ja tolliameti maksuvõlgade sissenõudmise osakonna juht Raul Siem teeb ülevaate eraisikutest maksumaksjate ja ettevõtete maksuvõlgadest 2004. aastal ning selgitab maksuvõlgade ennetamise ja sissenõudmise protseduuri

  11. Valmis film parvlaev Estonia katastroofist / Imre Kaas

    Index Scriptorium Estoniae

    Kaas, Imre

    2003-01-01

    Saksamaal on valminud poliitiline põnevusfilm "Balti torm" ("Baltic Storm"), mis kujutab parvlaev "Estonia" hukku venelaste vandenõu tulemusena. Film jõuab Eestis linale novembri alul. Produtsent ja esialgse stsenaariumi autor koosHenning Wittega on Jutta Rabe, režissöör ja üks stsenariste Reuben Leder. Kaasa teeb ka Donald Sutherland USA kindrali rollis. Eesti näitlejaist teeb kaasa Rein Oja

  12. Estonia ujub Saksamaa kinodesse / Andres Laasik, Heiki Suurkask

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2003-01-01

    Saksamaal Berliinis esilinastub pidulikult 13. oktoobril poliitiline põnevusfilm "Balti torm" ("Baltic Storm"), mis kujutab parvlaev "Estonia" hukku. Režissöör ja üks stsenariste on Reuben Leder, peaosades Greta Scacchi ja Jürgen Prochnow. Kaasa teeb ka Donald Sutherland USA kindrali rollis. Eesti näitlejaist teeb kaasa Rein Oja. Põhjamaades on filmi linastamine kahtluse all

  13. Data Corrections and Wind-Tunnel Data Comparisons of a 5% TCA Model in the NASA Ames 12-ft Pressure Tunnel

    Science.gov (United States)

    Zuniga, Fanny A.

    1999-01-01

    The objectives of this research are: 1) To determine the effect of geometric variations near the inboard leading-edge flap on high-lift and stability and control performance data; 2) To determine Re effects on TCA (Technology Concept Aircraft) high-lift configuration for optimum high-lift and stability and control performance at takeoff, climbout, approach and landing conditions; and 3) To obtain flow-visualization data on upper surface of wing for CFD validations. This paper is presented in viewgraph form.

  14. Technical Reference Manual to Allied Medical Publication 7.5 (AMedP 7.5) NATO Planning Guide for the Estimation of CBRN Casualties

    Science.gov (United States)

    2016-10-01

    algorithm enable this direct quantification. Three basic steps characterize each Monte Carlo trial. First, obtain a random incubation or latent period...18-3  3.  Incubation /Latent Period...3.  Incubation Period .................................................................................... 19-4  4.  Injury Profile

  15. Inhalation Anthrax (Ames aerosol) in Naive and Vaccinated New Zealand Rabbits: Characterizing the Spread of Bacteria from Lung Deposition to Bacteremia

    Science.gov (United States)

    2012-06-28

    rabbits as measured by dilution plate analysis of homogenized lung tissue or bronchoalveolar lavage (BAL) fluid. After 6 and 36 h, >80% and >96...QUANTIFICATION OF BACTERIA AND ALVEOLAR MACROPHAGES IN BRONCHOALVEOLAR LAVAGE (BAL) FLUID The bacterial load in the conducting airways at a given time...point post-exposure was a main data set we aimed to collect in this work and CFU were determined by dilution plate analysis of bronchoalveolar lavage

  16. Safety Evaluation of Multiple Strains of Lactobacillus plantarum and Pediococcus pentosaceus in Wistar Rats Based on the Ames Test and a 28-Day Feeding Study

    Directory of Open Access Journals (Sweden)

    Cheng-Chih Tsai

    2014-01-01

    Full Text Available Three lactic acid bacterial strains, Lactobacillus plantarum, HK006, and HK109, and Pediococcus pentosaceus PP31 exhibit probiotic potential as antiallergy agents, both in vitro and in vivo. However, the safety of these new strains requires evaluation when isolated from infant faeces or pickled cabbage. Multiple strains (HK006, HK109, and PP31 were subject to a bacterial reverse mutation assay and a short-term oral toxicity study. The powder product exhibited mutagenic potential in Salmonella Typhimurium strains TA98 and TA1535 (with or without metabolic activation. In the short-term oral toxicity study, rats received a normal dosage of 390 mg/kg/d (approximately 9×109 CFU/kg/d or a high dosage of 1950 mg/kg/d (approximately 4.5×1010 CFU/kg/d for 28 d. No adverse effects were observed regarding the general condition, behaviour, growth, feed and water consumption, haematology, clinical chemistry indices, organ weights, or histopathologic analysis of the rats. These studies have demonstrated that the consumption of multiple bacterial strains is not associated with any signs of mutagenicity of S. Typhimurium or toxicity in Wistar rats, even after consuming large quantities of bacteria.

  17. Ames interactive molecular model building system - A 3-D computer modelling system applied to the study of the origin of life

    Science.gov (United States)

    Coeckelenbergh, Y.; Macelroy, R. D.; Rein, R.

    1978-01-01

    The investigation of specific interactions among biological molecules must take into consideration the stereochemistry of the structures. Thus, models of the molecules are essential for describing the spatial organization of potentially interacting groups, and estimations of conformation are required for a description of spatial organization. Both the function of visualizing molecules, and that of estimating conformation through calculations of energy, are part of the molecular modeling system described in the present paper. The potential uses of the system in investigating some aspects of the origin of life rest on the assumption that translation of conformation from genetic elements to catalytic elements would have been required for the development of the first replicating systems subject to the process of biological evolution.

  18. Reaction and fission cross-sections of 750AMeV 238U ions on Pb, Cu and AI-targets

    International Nuclear Information System (INIS)

    Hesse, M.; Aumann, T.; Czajkowski, S.; Dessagne, P.; Hanelt, E.; Kozhuharov, C.; Miehe, C.; Pfuetzner, M.; Roehl, C.; Schwab, W.; Stephan, C.; Tassan-Got, L.

    1995-09-01

    Charge-loss and fission cross-sections of 238 U at 750 A.MeV were measured on Al, Cu and Pb targets. The charge-loss rate was obtained by the attenuation method. Fission was selected by detecting the pair of highly ionizing fragments. Since the neutron-loss cross sections were measured in a parallel experiment for the same projectiles, all cross sections contributing to 238 U collisions on nuclei are available now as function of the target mass number and can be compared with current models. (orig.)

  19. El ñame espino (Dioscorea rotundata Poir.: una opción en la producción de jarabes edulcorantes intermedios para la industria alimentaria

    Directory of Open Access Journals (Sweden)

    Carlos Ramón Vidal Tovar

    2010-10-01

    Full Text Available The principal objective of this study was the production of intermediate syrups by enzymatic hydrolysis using the enzyme α-amylase on solutions of 36 and 46% (D. rotundata The response variable was the dextrose equivalent in each syrup obtained. A completely randomized design was used. The data was analyzed using Statgraphics ® statistical package. The products obtained were intermediate sweeteners syrups with a dextrose equivalent of 18.81 and 22.15%, respectively; after liquefaction, -which allows classification as a low conversion syrup because of its low content of glucose syrups- the syrups obtained can be used for their functional properties as intermediate syrups or as raw material for various food industry processes such as fermentation by yeast or obtaining syrups rich in glucose by saccharification. This allows establishing a guideline for the use of yam as a non-conventional raw material in the production of products from starch.

  20. Art Inuit : Formes de l'Ame et Représentations de l'Etre. : Histoire de l'art et anthropologie

    OpenAIRE

    Pelaudeix , Cecile

    2007-01-01

    Relying on extensive field work, both in remote Arctic communities and outpost camps, and inside Canadian art collections, Cecile Pelaudeix's book presents a critical analysis of the Western perception of Inuit art, the theoretical assumptions underlying art history and anthropology discourse, and proposes a renewed interpretation of Kenojuak Ashevak's work (1959-2002), as well as a new understanding of contemporary Inuit art works at large. The author accords art work a deep meaning by revea...

  1. Rotorcraft In-Flight Simulation Research at NASA Ames Research Center: A Review of the 1980's and plans for the 1990's

    Science.gov (United States)

    Aiken, Edwin W.; Hindson, William S.; Lebacqz, J. Victor; Denery, Dallas G.; Eshow, Michelle M.

    1991-01-01

    A new flight research vehicle, the Rotorcraft-Aircrew System Concepts Airborne Laboratory (RASCAL), is being developed by the U.S. Army and NASA at ARC. The requirements for this new facility stem from a perception of rotorcraft system technology requirements for the next decade together with operational experience with the Boeing Vertol CH-47B research helicopter that was operated as an in-flight simulator at ARC during the past 10 years. Accordingly, both the principal design features of the CH-47B variable-stability system and the flight-control and cockpit-display programs that were conducted using this aircraft at ARC are reviewed. Another U.S Army helicopter, a Sikorsky UH-60A Black Hawk, was selected as the baseline vehicle for the RASCAL. The research programs that influence the design of the RASCAL are summarized, and the resultant requirements for the RASCAL research system are described. These research programs include investigations of advanced, integrated control concepts for achieving high levels of agility and maneuverability, and guidance technologies, employing computer/sensor-aiding, designed to assist the pilot during low-altitude flight in conditions of limited visibility. The approach to the development of the new facility is presented and selected plans for the preliminary design of the RASCAL are described.

  2. Simulation and control engineering studies of NASA-Ames 40 foot by 80 foot/80 foot by 120 foot wind tunnels

    Science.gov (United States)

    Bohn, J. G.; Jones, J. E.

    1978-01-01

    The development and use of a digital computer simulation of the proposed wind tunnel facility is described. The feasibility of automatic control of wind tunnel airspeed and other parameters was examined. Specifications and implementation recommendations for a computer based automatic control and monitoring system are presented.

  3. A Computer-Interpretable Version of the AACE, AME, ETA Medical Guidelines for Clinical Practice for the Diagnosis and Management of Thyroid Nodules

    DEFF Research Database (Denmark)

    Peleg, Mor; Fox, John; Patkar, Vivek

    2014-01-01

    Objective: Clinical practice guidelines (CPGs) could have a more consistent and meaningful impact on clinician behavior if they were delivered as electronic algorithms that provide patient-specific advice during patient-physician encounters. We developed a computer-interpretable algorithm for U.S...

  4. Ames Infusion Stories for NASA Annual Technology Report: Development of an Ablative 3D Quartz / Cyanate Ester Composite Multi-Functional Material for the Orion Spacecraft Compression Pad

    Science.gov (United States)

    Smith, Brandon; Jan, Darrell Leslie; Venkatapathy, Ethiraj

    2015-01-01

    Vehicles re-entering Earth's atmosphere require protection from the heat of atmospheric friction. The Orion Multi-Purpose Crew Vehicle (MPCV) has more demanding thermal protection system (TPS) requirements than the Low Earth Orbit (LEO) missions, especially in regions where the structural load passes through. The use of 2-dimensional laminate materials along with a metal insert, used in EFT1 flight test for the compression pad region, are deemed adequate but cannot be extended for Lunar return missions.

  5. Allied Medical Publication AMedP-7.6(A), Commander’s Guide to Medical Operations in Support of CBRN Defensive Operations: Study Draft 1

    Science.gov (United States)

    2015-07-01

    potential adverse reactions and/or operational degradation. 4. As noted in Chapter 1, a CBRN environment presents a number of unique challenges for...Surveillance Centre (DHSC) National forces— veterinary , public health, occupational health National reach-back capabilities Guidance on issues...countermeasures and seek attack? appropriate authority to use them lmmunise personnel (if suitable vaccine available) ID particularly vulnerable targets

  6. How self-determination theory can assist our understanding of the teaching and learning processes in medical education. AMEE guide No. 59.

    Science.gov (United States)

    Ten Cate, Th J; Kusurkar, Rashmi A; Williams, Geoffrey C

    2011-01-01

    Self-determination Theory (SDT), designed by Edward Deci and Richard Ryan, serves among the current major motivational theories in psychology. SDT research has been conducted in many areas, among which are education and health care, but its applications in medical education are rare. The potential of SDT to help understand processes in medical education justifies this Guide. SDT is explained in seven principles, one of which is the distinction of three innate psychological needs of human beings: for competence, for autonomy and for relatedness. Further, SDT elaborates how humans tend to internalise regulation of behaviour that initially has been external, in order to develop autonomous, self-determined behaviour. Implications of SDT for medical education are discussed with reference to preparation and selection, curriculum structure, classroom teaching, assessments and examinations, self-directed learning, clinical teaching, students as teachers and researchers, continuing professional development, faculty development and stress among trainees.

  7. 4C/ID in medical education: How to design an educational program based on whole-task learning: AMEE Guide No. 93.

    Science.gov (United States)

    Vandewaetere, Mieke; Manhaeve, Dominique; Aertgeerts, Bert; Clarebout, Geraldine; Van Merriënboer, Jeroen J G; Roex, Ann

    2015-01-01

    Medical education increasingly stresses that medical students should be prepared to take up multiple roles as a health professional. This requires the integrated acquisition of multiple competences such as clinical reasoning and decision making, communication skills and management skills. To promote such complex learning, instructional design has focused on the use of authentic, real-life learning tasks that students perform in a real or simulated task environment. The four-component instructional design model (4C/ID) model is an instructional design model that starts from the use of such tasks and provides students with a variety of learning tools facilitating the integrated acquisition of knowledge, skills and attitudes. In what follows, we guide the reader on how to implement educational programs based on the 4C/ID model and illustrate this with an example from general practice education. The developed learning environment is in line with the whole-task approach, where a learning domain is considered as a coherent, integrated whole and where teaching progresses from offering relatively simple, but meaningful, authentic whole tasks to more complex tasks. We describe the steps that were taken, from prototype over development to implementation, to build five learning modules (patient with diabetes; the young child with fever; axial skeleton; care for the elderly and physically undefined symptoms) that all focus on the integrated acquisition of the Canadian Medical Education Directives for Specialists roles in general practice. Furthermore, a change cycle for educational innovation is described that encompasses practice-based challenges and pitfalls about the collaboration between different stakeholders (students, developers and teachers) and the transition from traditional, fragmented and classroom-based learning to integrated and blended learning based on sound instructional design principles.

  8. Floral structure of two species of Bulbophyllum section Cirrhopetalum Lindl.: B. weberi Ames and B. cumingii (Lindl.) Rchb. f. (Bulbophyllinae Schltr., Orchidaceae).

    Science.gov (United States)

    Kowalkowska, Agnieszka K; Turzyński, Sławomir; Kozieradzka-Kiszkurno, Małgorzata; Wiśniewska, Natalia

    2017-05-01

    Flowers of Bulbophyllum weberi and B. cumingii are characterized by fly-pollinated features. The secretory activity was described in dorsal sepals in both species (putative osmophores), petals in B. weberi (possible osmophores) and adaxial surface of lips in both species. In the cells of dorsal sepals and petals of B. weberi proteins, dihydroxyphenols, lipids and starch grains were detected, in lateral sepals-lipids. Whereas in dorsal sepal of B. cumingii only lipids and starch grains were noted, in lateral sepals-proteins and dihydroxyphenols and in petals-proteins and starch grains. The lips in both species differed histochemically and ultrastructurally. The epidermal cells of lip groove in B. weberi contained lipids, proteins, starch grains in cytoplasm, dihydroxyphenols in vacuoles and pectic acids/mucilage on surface. Whereas in B. cumingii-few lipids, starch grains, no proteins, no dihydroxyphenols and no mucilage were noted. Ultrastructurally, in B. weberi, the secretory material was present on surface and vesicles building into plasmalemma, while in B. cumingii-cell wall ingrowths and microchannels in cuticle. The osmiophilic irregular materials and globular, osmiophilic globules in B. weberi are probably tannin-like materials. For the first time, we described the cell wall ingrowths in Bulbophyllum species: in lip of B. cumingii and petals of B. weberi.

  9. El tipo de gelificante en el desarrollo in vitro y la aclimatizacion de plantas de Yampi (dioscorea trifida y ñame (dioscorea alata

    Directory of Open Access Journals (Sweden)

    Ana Gabriela Chacón

    2000-01-01

    Full Text Available El yampf y el name se cultivan en ~osta Rica primordial mente con fines de exportaci6n; sin embargo, su producci6n se ve seriamente li- mitada por la falta de semilla libre de plagas y enfermedades. La producci6n in vitro de semilla representa una altemativa a esta problematic a, pero este proceso debe a su vez ser optimizado. El presente trabajo evalu6 el efecto de 2 gelifi- cantes sobre el crecimiento in vitro y en invema- dero de plantas de D. trifida y D. alata. Se en- contr6 que, en general, el crecimiento in vitro y en invemadero de las plantas se ve favorecido en ambas especies por el uso del Phytagel@ a 1.3 y 1.8 g/L. Ademas, el subcultivo de plantas de D. alata con sfntomas de hiperhidricidad en medio solidificado con agar redujo considerablemente estos sfntomas.

  10. Aetiology of acute meningoencephalitis in Cambodian children, 2010-2013

    NARCIS (Netherlands)

    Horwood, Paul F.; Duong, Veasna; Laurent, Denis; Mey, Channa; Sothy, Heng; Santy, Ky; Richner, Beat; Heng, Seiha; Hem, Sopheak; Cheval, Justine; Gorman, Christopher; Dussart, Philippe; de Jong, Menno D.; Kerleguer, Alexandra; Guillard, Bertrand; Murgue, Bernadette; Lecuit, Marc; de Lamballerie, Xavier; Farrar, Jeremy J.; Tarantola, Arnaud; Eloit, Marc; Buchy, Philippe

    2017-01-01

    Acute meningoencephalitis (AME) is associated with considerable morbidity and mortality in children in developing countries. Clinical specimens were collected from children presenting with AME at two Cambodian paediatric hospitals to determine the major aetiologies associated with AME in the

  11. Kak razvivat tramvainuju set Tallinna? / Reedik Võrno

    Index Scriptorium Estoniae

    Võrno, Reedik

    2006-01-01

    Projektist "Tallinna tramm", mille teostatavusuuringu teeb konsortsium, mis ühendab Prantsuse konsultatsioonifirmat Systra, AS-i ETP Grupp ning Hendrikson & Ko. Lk. 16-17 võrdluseks valik rööbastranspordi skeeme Saksamaa ja Šveitsi linnades

  12. The aftermath of the Soviet occupation in Estonia / Liisi Bucht

    Index Scriptorium Estoniae

    Bucht, Liisi

    2000-01-01

    Autor teeb kokkuvõtte Teise maailmasõja ja Nõukogude okupatsiooni järelmõjudest: ühiskonnas toimusid demograafilised muutused, Eesti majanduslik areng seiskus, intelligents ja ettevõtlikum osa rahvast hävitati või pages välismaale

  13. Kas internet muudab meid rumalamaks? / Liis Kängsepp

    Index Scriptorium Estoniae

    Kängsepp, Liis, 1981-

    2012-01-01

    Raamatust: Carr, Nicholas. Triiv madalikule : mida Internet meie ajuga teeb / tõlkija Tiina Randus. Tallinn : Äripäev, 2012. (Äripäeva raamat). Ka intervjuu Tallinna Ülikooli dotsendi Kristjan Pordiga raamatus esitatud väidetest interneti mõjust inimesele

  14. Helmes viib mobiilse parkimise ka USA-sse / Toivo Tänavsuu

    Index Scriptorium Estoniae

    Tänavsuu, Toivo

    2007-01-01

    IT-firma Helmes peab läbirääkimisi umbes 30 linnaga mobiilse parkimise teenuse pakkumiseks. Helmes teeb koostööd Euroopa suurima parklaoperaatori APCOA-ga, neil on Belgias loodud ühisfirma Mobile4, selle turuosa Belgias on ligi 10%. Lisa: EMT kõrbes Norras m-parkimisega

  15. Christoph Kummerer (Pocketnoise) / Christoph Kummerer ; interv. Tilman Baumgärtel

    Index Scriptorium Estoniae

    Kummerer, Christoph, 1974-

    2006-01-01

    Austria kunstnikust, muusikust ja programmeerijast Christoph Kummererist (sünd. 1974), kes teeb Gameboyga tehnomuusikat. Loodud tarkvara nimetab ta Pocketnoise'iks, oma kompositsioonide levitamiseks kasutab võrgukaubamärki pilot.fm, mille ta asutas eksperimentaalse elektroonilise online-muusika levitamiseks. 30. I 2001 toimunud telefoniintervjuu kunstniku ja muusikuga

  16. Arusaamatused eluasemelaenu intressi tulumaksusoodustusega / Hiie Õunpuu

    Index Scriptorium Estoniae

    Õunpuu, Hiie

    2005-01-01

    Eluasemelaenu intresside tulust mahaarvamise kohta. Lisatud: Kask, Evelyn. Maksusoodustuse mõte on toetada eluaseme soetamist, lk. 34 ; Lehis, Lasse. MTA teeb liiga suuri üldistusi, lk. 34. Vt. ka Maksumaksja 2005, nr 2, lk 21-24. - Vt. ka: http://www.maksumaksjad.ee/modules/smartsection/item.php?itemid=78 ; http://www.maksumaksjad.ee/modules/smartsection/item.php?itemid=79.

  17. Vene draamateatri maja avatakse mais endisaegses hiilguses / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2006-01-01

    Vene draamateatri, endise esinduskino "Gloria Palace'i" rekonstrueerimisest ja juurdeehitusest. Saali rekonstrueerimistöid teeb OÜ Vana Tallinn koostöös KAR-Grupiga, juurdeehituse projekteeris arhitekt Ra Luhse büroost Luhse ja Tuhal. Läti arhitekti Fridrihs Skujinsi projekteeritud "Gloria Palace" valmis 1926. a. Kommentaar "Pealinna esinduskino mall võeti Riiast"

  18. MILREM extends THeMIS mission set / Huw Williams

    Index Scriptorium Estoniae

    Williams, Huw

    2016-01-01

    Eesti kaitsetehnika ettevõte MILREM OÜ täiendab oma relvasüsteemi THeMIS ja teeb selleks koostööd mitmete firmadega. Tulevikus soovitakse lisaks Eesti kaitseväele teha koostööd ka Läti kaitseväega ja kasutada sõjatehnikat sealsetel õppustel

  19. Plats puhtaks! / Jaanus Karilaid

    Index Scriptorium Estoniae

    Karilaid, Jaanus, 1977-

    2007-01-01

    Ilmunud ka: Lääne Elu, 13. nov. 2007, lk. 2. Keskerakonna Läänemaa piirkonna esimees vaatleb Eesti poliitilist maastikku aastail 1988-1991, kui iseseisvusreferendumil hääletas 150 000 eestivenelast iseseisvuse poolt, mis oli Rahvarinde teene, ning endiste punategelastest poliitikute populaarsust, mis teeb platsipuhastamise võimatuks. Reformierakonna poliitikute tegevuse kriitika

  20. Tiitelleht olgu asjalik / Oskar Kruus

    Index Scriptorium Estoniae

    Kruus, Oskar, 1929-2007

    2001-01-01

    Arvustus: Veskimägi, Kaljo-Olev. Kahte kappi on ühhetassa maja tarvis... : Eesti raamatukogude ajalugu. Tallinn : K.-O. Veskimägi, 2000 ; Toona, Elin. Rõõm teeb taeva taga tuld : Ernst Enno. Tartu : Ilmamaa, 2000