Building Climate Resilience at NASA Ames Research Center

Science.gov (United States)

Iraci, L. T.; Mueller, C.; Podolske, J. R.; Milesi, C.

2016-12-01

NASA Ames Research Center, located at the southern end of the San Francisco Bay (SFB) estuary, has identified three primary vulnerabilities to changes in climate. The Ames Climate Adaptation Science Investigator (CASI) workgroup has studied each of these challenges to operations and the potential exposure of infrastructure and employees to an increased frequency of hazards. Sea level rise inundation scenarios for the SFB Area generally refer to projected scenarios in mean sea level rather than changes in extreme tides that could occur during future storm conditions. In the summer of 2014, high resolution 3-D mapping of the low-lying portion of Ames was performed. Those data are integrated with improved sea level inundation scenarios to identify the buildings, basements and drainage systems potentially affected. We will also identify the impacts of sea level and storm surge effects on transportation to and from the Center. This information will help Center management develop future master plans. Climate change will also lead to changes in temperature, storm frequency and intensity. These changes have potential impacts on localized floods and ecosystems, as well as on electricity and water availability. Over the coming decades, these changes will be imposed on top of ongoing land use and land cover changes, especially those deriving from continued urbanization and increase in impervious surface areas. These coupled changes have the potential to create a series of cascading impacts on ecosystems, including changes in primary productivity and disturbance of hydrological properties and increased flood risk. The majority of the electricity used at Ames is supplied by hydroelectric dams, which will be influenced by reductions in precipitation or changes in the timing or phase of precipitation which reduces snow pack. Coupled with increased demand for summertime air conditioning and other cooling needs, NASA Ames is at risk for electricity shortfalls. To assess the

The ames network and the task group on WWER's

International Nuclear Information System (INIS)

Davies, L.M.; Duysen, J.C. van; Estorff, U. von; Sycamore, D.

1997-01-01

The European Network on 'Ageing Materials Evaluation and Studies' (AMES) was created in 1993. Its main objectives are (a) to provide information and understanding on neutron irradiation effects in reactor materials in support of designers, operators, regulators and researchers and (b) to establish and discharge projects in the above areas. The Steering Committee is composed of at least one participant from each nuclear European Union country. The JRC's Institute for Advanced Materials of the European Commission plays the role of Operating Agent and Manager of the AMES Network. This paper describes the structure, objectives, and major projects of the AMES network. Particular emphasis is placed upon the work it is intended to perform within the Task Group on 'WWER's of the first AMES project (AMES1) on 'Validation of surveillance practice and mitigation methods'. EC DGXVII is addressing the question of how to facilitate contacts between EU and Russian industries in the framework of nuclear Industrial co-operation, and this project may provide a suitable starting point upon which to develop a basis for further work of mutual interest. (author)

Atmosphere of Freedom: Sixty Years at the NASA Ames Research Center

Science.gov (United States)

Bugos, Glenn E.; Launius, Roger (Technical Monitor)

2000-01-01

Throughout Ames History, four themes prevail: a commitment to hiring the best people; cutting-edge research tools; project management that gets things done faster, better and cheaper; and outstanding research efforts that serve the scientific professions and the nation. More than any other NASA Center, Ames remains shaped by its origins in the NACA (National Advisory Committee for Aeronautics). Not that its missions remain the same. Sure, Ames still houses the world's greatest collection of wind tunnels and simulation facilities, its aerodynamicists remain among the best in the world, and pilots and engineers still come for advice on how to build better aircraft. But that is increasingly part of Ames' past. Ames people have embraced two other missions for its future. First, intelligent systems and information science will help NASA use new tools in supercomputing, networking, telepresence and robotics. Second, astrobiology will explore lore the prospects for life on Earth and beyond. Both new missions leverage Ames long-standing expertise in computation and in the life sciences, as well as its relations with the computing and biotechnology firms working in the Silicon Valley community that has sprung up around the Center. Rather than the NACA missions, it is the NACA culture that still permeates Ames. The Ames way of research management privileges the scientists and engineers working in the laboratories. They work in an atmosphere of freedom, laced with the expectation of integrity and responsibility. Ames researchers are free to define their research goals and define how they contribute to the national good. They are expected to keep their fingers on the pulse of their disciplines, to be ambitious yet frugal in organizing their efforts, and to always test their theories in the laboratory or in the field. Ames' leadership ranks, traditionally, are cultivated within this scientific community. Rather than manage and supervise these researchers, Ames leadership merely

AmE 2012. Automotive meets electronics

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-11-01

This conference CD contains 19 contributions, which were presented at the AmE 2012. The main topics were: (1) Electrification; (2) High voltage (board networks) and electromagnetic compatibility; (3) Car-to-X and driver assistance; (4) Diagnosis; (5) Electrical systems. Six contributions were recorded separately for the ENERGY database. [German] Diese Tagungs-CD enthaelt 19 Beitraege, die auf der AmE 2012 vorgestellt wurden. Die Themenschwerpunkte waren: 1. Electrification; 2. Hochvolt(-bordnetze) und Elektromagnetische Vertraeglichkeit; 3. Car-to-X und Fahrerassistenz; 4. Diagnose; 5. Bordnetze. Sechs Beitraege wurden separat fuer die ENERGY-Datenbank aufgenommen.

Spatial delayed nonmatching-to-sample performances in long-living Ames dwarf mice.

Science.gov (United States)

Derenne, Adam; Brown-Borg, Holly M; Martner, Sarah; Wolff, Wendy; Frerking, Morgan

2014-01-17

Ames dwarf mice have an extended lifespan by comparison with normal mice. Behavioral testing has revealed that sometimes Ames dwarf mice also evince superior performances relative to normal mice, but in other cases they do not. In this experiment, Ames dwarf and normal mice were compared on a T-maze test and on a delayed nonmatching-to-sample variant of a T-maze test. On the simple T-maze, Ames dwarf and normal mice committed comparable numbers of errors. On the nonmatching-to-sample task, normal mice mastered the discrimination by the end of the experiment while Ames dwarf mice did not. The apparatus, distances traveled and session duration were equivalent between the two tasks. The poorer performances of Ames dwarf mice on the nonmatching-to-sample task suggests that Ames dwarf mice may not be as capable of learning relatively cognitively complex tasks as normal mice. © 2013.

Functionally enhanced brown adipose tissue in Ames dwarf mice.

Science.gov (United States)

Darcy, Justin; Bartke, Andrzej

2017-01-02

Reduced insulin-like growth factor 1/insulin signaling (IIS) has been linked to extended longevity in species ranging from yeast to mammals. In mammals, this is exemplified in Ames dwarf (Prop1 df/df ) mice, which have a 40%-60% increase in longevity (males and females, respectively) due to their recessive Prop1 loss-of-function mutation that results in lack of growth hormone (GH), thyroid-stimulating hormone and prolactin. Our laboratory has previously shown that Ames dwarf mice have functionally unique white adipose tissue (WAT) that improves, rather than impairs, insulin sensitivity. Because GH and thyroid hormone are integral to adipose tissue development and function, we hypothesized that brown adipose tissue (BAT) in Ames dwarf mice may also be functionally unique and/or enhanced. Here, we elaborate on our recent findings, which demonstrate that BAT is functionally enhanced in Ames dwarf mice, and suggest that BAT removal in these mice results in utilization of WAT depots as an energy source. We also discuss how our findings compare to those in other long-lived dwarf mice with altered IIS, which unlike Ames dwarf mice, are essentially euthyroid. Lastly, we provide some insights into the implications of these findings and discuss some of the necessary future work in this area.

Mitochondrial electron transport chain functions in long-lived Ames dwarf mice

Science.gov (United States)

Choksi, Kashyap B.; Nuss, Jonathan E.; DeFord, James H.; Papaconstantinou, John

2011-01-01

The age-associated decline in tissue function has been attributed to ROS-mediated oxidative damage due to mitochondrial dysfunction. The long-lived Ames dwarf mouse exhibits resistance to oxidative stress, a physiological characteristic of longevity. It is not known, however, whether there are differences in the electron transport chain (ETC) functions in Ames tissues that are associated with their longevity. In these studies we analyzed enzyme activities of ETC complexes, CI-CV and the coupled CI-CII and CII-CIII activities of mitochondria from several tissues of young, middle aged and old Ames dwarf mice and their corresponding wild type controls to identify potential mitochondrial prolongevity functions. Our studies indicate that post-mitotic heart and skeletal muscle from Ames and wild-type mice show similar changes in ETC complex activities with aging, with the exception of complex IV. Furthermore, the kidney, a slowly proliferating tissue, shows dramatic differences in ETC functions unique to the Ames mice. Our data show that there are tissue specific mitochondrial functions that are characteristic of certain tissues of the long-lived Ames mouse. We propose that this may be a factor in the determination of extended lifespan of dwarf mice. PMID:21934186

Hepatic response to oxidative injury in long-lived Ames dwarf mice.

Science.gov (United States)

Sun, Liou Y; Bokov, Alex F; Richardson, Arlan; Miller, Richard A

2011-01-01

Multiple stress resistance pathways were evaluated in the liver of Ames dwarf mice before and after exposure to the oxidative toxin diquat, seeking clues to the exceptional longevity conferred by this mutation. Before diquat treatment, Ames dwarf mice, compared with nonmutant littermate controls, had 2- to 6-fold higher levels of expression of mRNAs for immediate early genes and 2- to 5-fold higher levels of mRNAs for genes dependent on the transcription factor Nrf2. Diquat led to a 2-fold increase in phosphorylation of the stress kinase ERK in control (but not Ames dwarf) mice and to a 50% increase in phosphorylation of the kinase JNK2 in Ames dwarf (but not control) mice. Diquat induction of Nrf2 protein was higher in dwarf mice than in controls. Of 6 Nrf2-responsive genes evaluated, 4 (HMOX, NQO-1, MT-1, and MT-2) remained 2- to 10-fold lower in control than in dwarf liver after diquat, and the other 2 (GCLM and TXNRD) reached levels already seen in dwarf liver at baseline. Thus, livers of Ames dwarf mice differ systematically from controls in multiple stress resistance pathways before and after exposure to diquat, suggesting mechanisms for stress resistance and extended longevity in Ames dwarf mice.

Brown Adipose Tissue Function Is Enhanced in Long-Lived, Male Ames Dwarf Mice

Science.gov (United States)

McFadden, Samuel; Fang, Yimin; Huber, Joshua A.; Zhang, Chi; Sun, Liou Y.; Bartke, Andrzej

2016-01-01

Ames dwarf mice (Prop1df/df) are long-lived due to a loss of function mutation, resulting in deficiency of GH, TSH, and prolactin. Along with a marked extension of longevity, Ames dwarf mice have improved energy metabolism as measured by an increase in their oxygen consumption and heat production, as well as a decrease in their respiratory quotient. Along with alterations in energy metabolism, Ames dwarf mice have a lower core body temperature. Moreover, Ames dwarf mice have functionally altered epididymal white adipose tissue (WAT) that improves, rather than impairs, their insulin sensitivity due to a shift from pro- to anti-inflammatory cytokine secretion. Given the unique phenotype of Ames dwarf epididymal WAT, their improved energy metabolism, and lower core body temperature, we hypothesized that Ames dwarf brown adipose tissue (BAT) may function differently from that of their normal littermates. Here we use histology and RT-PCR to demonstrate that Ames dwarf mice have enhanced BAT function. We also use interscapular BAT removal to demonstrate that BAT is necessary for Ames dwarf energy metabolism and thermogenesis, whereas it is less important for their normal littermates. Furthermore, we show that Ames dwarf mice are able to compensate for loss of interscapular BAT by using their WAT depots as an energy source. These findings demonstrate enhanced BAT function in animals with GH and thyroid hormone deficiencies, chronic reduction of body temperature, and remarkably extended longevity. PMID:27740871

AMES: Towards an Agile Method for ERP Selection

OpenAIRE

Juell-Skielse, Gustaf; Nilsson, Anders G.; Nordqvist, Andreas; Westergren, Mattias

2012-01-01

Conventional on-premise installations of ERP are now rapidly being replaced by ERP as service. Although ERP becomes more accessible and no longer requires local infrastructure, current selection methods do not take full advantage of the provided agility. In this paper we present AMES (Agile Method for ERP Selection), a novel method for ERP selection which better utilizes the strengths of service oriented ERP. AMES is designed to shorten lead time for selection, support identification of essen...

Evaluation of Genotoxicity of CSE1034 by Ames and In vitro ...

African Journals Online (AJOL)

NADPH) was obtained from Himedia (Mumbai, India). Ames test. The test was ..... W, Passarge E. Toxicity of antibiotics cultured human skin fibroblast. Humangenetik 1975; 28: 273-267. 15. McCann J, Choi E, Yamasaki E, Ames BN. Detection of.

Making Stuff Outreach at the Ames Laboratory and Iowa State University

Energy Technology Data Exchange (ETDEWEB)

Ament, Katherine; Karsjen, Steven; Leshem-Ackerman, Adah; King, Alexander

2011-04-01

The U. S. Department of Energy's Ames Laboratory in Ames, Iowa was a coalition partner for outreach activities connected with NOVA's Making Stuff television series on PBS. Volunteers affiliated with the Ames Laboratory and Iowa State University, with backgrounds in materials science, took part in activities including a science-themed Family Night at a local mall, Science Cafes at the Science Center of Iowa, teacher workshops, demonstrations at science nights in elementary and middle schools, and various other events. We describe a selection of the activities and present a summary of their outcomes and extent of their impact on Ames, Des Moines and the surrounding communities in Iowa. In Part 2, results of a volunteer attitude survey are presented, which shed some light on the volunteer experience and show how the volunteers participation in outreach activities has affected their views of materials education.

Radiological survey support activities for the decommissioning of the Ames Laboratory Research Reactor Facility, Ames, Iowa

Energy Technology Data Exchange (ETDEWEB)

Wynveen, R.A.; Smith, W.H.; Sholeen, C.M.; Justus, A.L.; Flynn, K.F.

1984-09-01

At the request of the Engineering Support Division of the US Department of Energy-Chicago Operations Office and in accordance with the programmatic overview/certification responsibilities of the Department of Energy Environmental and Safety Engineering Division, the Argonne National Laboratory Radiological Survey Group conducted a series of radiological measurements and tests at the Ames Laboratory Research Reactor located in Ames, Iowa. These measurements and tests were conducted during 1980 and 1981 while the reactor building was being decontaminated and decommissioned for the purpose of returning the building to general use. The results of these evaluations are included in this report. Although the surface contamination within the reactor building could presumably be reduced to negligible levels, the potential for airborne contamination from tritiated water vapor remains. This vapor emmanates from contamination within the concrete of the building and should be monitored until such time as it is reduced to background levels. 2 references, 8 figures, 6 tables.

NASA-Ames vertical gun

Science.gov (United States)

Schultz, P. H.

1984-01-01

A national facility, the NASA-Ames vertical gun range (AVGR) has an excellent reputation for revealing fundamental aspects of impact cratering that provide important constraints for planetary processes. The current logistics in accessing the AVGR, some of the past and ongoing experimental programs and their relevance, and the future role of this facility in planetary studies are reviewed. Publications resulting from experiments with the gun (1979 to 1984) are listed as well as the researchers and subjects studied.

Identification of Radiation Effects on Carcinogenic Food Estimated by Ames Test

International Nuclear Information System (INIS)

Afifi, M.; Eid, I.; El - Nagdy, M.; Zaher, R.; Abd El-Karem, H.; Abd EL Karim, A.

2016-01-01

A major concern in studies related to carcinogenesis is the exposure to the exogenous carcinogens that may occur in food in both natural and polluted human environments. The purpose of the present study is to examine some of food products by Ames test to find out if food products carcinogenic then expose food to gamma radiation to find out the effect of radiation on it as a treatment. In this study, the food samples were examined by Ames test (Salmonella typhimurium mutagenicity test) to find out that a food product could be carcinogenic or highly mutated. Testing of chemicals for mutagenicity is based on the knowledge that a substance which is mutagenic in the bacterium is more likely than not to be a carcinogen in laboratory animals, and thus , by extension, present a risk of cancer to humans. After that food products that showed mutagenicity exposed to gamma radiation at different doses to examine the effect of gamma radiation on food products. This study represent γ radiation effect on carcinogenic food by using Ames test in the following steps: Detect food by Ames test using Salmonella typhimurium strains in which the colony count /plate for each food sample will show if food is slightly mutated or highly mutated or carcinogenic. If food is highly mutated or carcinogenic with high number of colonies /plate, then the carcinogenic food or highly mutated food exposed to different doses of radiation The applied doses in this study were 0, 2.5, 5, and 10 (KGy). Detect the radiation effect on food samples by Ames test after irradiation. The study shows that mutated and carcinogenic food products estimated by Ames test could be treated by irradiation

Acquisition of steady-state operant behavior in long-living Ames Dwarf mice.

Science.gov (United States)

Derenne, Adam; Brown-Borg, Holly; Feltman, Kathryn; Corbett, Grant; Lackman, Serena

2011-10-24

Ames dwarf mice have a Prop-1 mutation that has been identified with increased levels of IGF-I in the central nervous system, upregulation of neuroprotective systems, and increased lifespan. To elucidate the behavioral effects of the Prop-1 mutation, 8 Ames dwarf and 7 normal mice (all of whom were 8 months of age or younger) were compared on a differential-reinforcement-of-low-rate-of-responding schedule of reinforcement and a matching-to-sample task. On both tasks, nosepokes were reinforced with access to a saccharin solution. Comparisons were based on several measures of behavioral efficiency: pause durations, intertrial intervals, and numbers of responses. Ames dwarf mice were generally less efficient than normal mice. One possible cause of this outcome is that relatively young Ames dwarf mice show less cognitive development than age-matched normal mice. Copyright © 2011 Elsevier Inc. All rights reserved.

Cultivating a Grassroots Aerospace Innovation Culture at NASA Ames Research Center

Science.gov (United States)

D'Souza, Sarah; Sanchez, Hugo; Lewis, Ryan

2017-01-01

This paper details the adaptation of specific 'knowledge production' methods to implement a first of its kind, grassroots event that provokes a cultural change in how the NASA Ames civil servant community engages in the creation and selection of innovative ideas. Historically, selection of innovative proposals at NASA Ames Research Center is done at the highest levels of management, isolating the views and perspectives of the larger civil servant community. Additionally, NASA innovation programs are typically open to technical organizations and do not engage non-technical organizations to bring forward innovative processes/business practices. Finally, collaboration on innovative ideas and associated solutions tend to be isolated to organizational silos. In this environment, not all Ames employees feel empowered to innovate and opportunities for employee collaboration are limited. In order to address these issues, the 'innovation contest' method was adapted to create the NASA Ames Innovation Fair, a unique, grassroots innovation opportunity for the civil servant community. The Innovation Fair consisted of a physical event with a virtual component. The physical event provided innovators the opportunity to collaborate and pitch their innovations to the NASA Ames community. The civil servant community then voted for the projects that they viewed as innovative and would contribute to NASA's core mission, making this event a truly grassroots effort. The Innovation Fair website provided a location for additional knowledge sharing, discussion, and voting. On March 3rd, 2016, the 'First Annual NASA Ames Innovation Fair' was held with 49 innovators and more than 300 participants collaborating and/or voting for the best innovations. Based on the voting results, seven projects were awarded seed funding for projects ranging from innovative cost models to innovations in aerospace technology. Surveys of both innovators and Fair participants show the Innovation Fair was successful

Ames-2016 line lists for 13 isotopologues of CO2: Updates, consistency, and remaining issues

Science.gov (United States)

Huang (黄新川), Xinchuan; Schwenke, David W.; Freedman, Richard S.; Lee, Timothy J.

2017-12-01

A new 626-based Ames-2 PES refinement and Ames-2016 line lists for 13 CO2 isotopologues are reported. A consistent σRMS = ±0.02 cm-1 is established for hundreds of isotopologue band origins using the Ames-2 PES. Ames-2016 line lists are computed at 296 K, 1000 K and 4000 K using the Ames-2 PES and the same DMS-N2 dipole surface used previously, with J up to 150, E‧ up to 24,000 cm-1 or 18,000 cm-1 and appropriate intensity cutoffs. The lists are compared to the CDSD-296, CDSD-4000 databases, UCL line lists, and a few recent highly accurate CO2 intensity measurements. Both agreements and discrepancies are discussed. Compared to the old Ames CO2 lists, the Ames-2016 line lists have line position deviations reduced by 50% or more, which consequently leads to more reliable intensities. The line shape parameters in the Ames-2016 line lists are predicted using the newly assigned conventional vibrational polyad quantum numbers for rovibrational levels below 12,000 cm-1 so the quality of the line shape parameters is similar to that of CDSD or HITRAN. This study further proves that a semi-empirically refined PES (Ames-1 and Ames-2) coupled with a high quality ab initio DMS (DMS-N2 and UCL) may generate IR predictions with consistent accuracy and is thus helpful in the analysis of laboratory spectra and simulations of various isotopologues. The Ames-2016 lists based on DMS-N2 have reached the ∼1% intensity prediction accuracy level for the recent 626 30013-00001 and 20013-00001 bands, but further quantification and improvements require sub-percent or sub-half-percent accurate experimental intensities. The inter-isotopologue consistency of the intensity prediction accuracies should have reached better than 1-3% for regular bands not affected by resonances. Since the Effective Dipole Models (EDM) in CDSD and HITRAN have 1-20% or even larger uncertainties, we show that the Ames lists can provide better alternative IR data for many hard-to-determine isotopologue bands

Ames Laboratory Site Environmental Report, Calendar year 1991

International Nuclear Information System (INIS)

Mathison, L.

1991-01-01

The summarized data and conclusions from the Ames Laboratory environmental monitoring program are presented in this Annual Site Environmental Report. This program is a working requirement of Department of Energy (DOE) Order 5484.1, ''Environmental Protection, Safety, and Health Protection Information Reporting Requirements'' and Order 5400.1, ''General Environmental Protection Program.'' Ames Laboratory is located on the campus of Iowa State University (ISU) and occupies several buildings owned by the DOE. The Laboratory also leases space in ISU-owned buildings. Laboratory research activities involve less than ten percent of the total chemical use and one percent of the radioisotope use on the ISU campus. Ames Laboratory is responsible for a small chemical burial site, located on ISU property. The site was used for the disposal of chemical and metal slags from thorium and uranium production. Samples of water from existing test wells and upstream and downstream sites on the nearby Squaw Creek show no detectable migration of the contents of the burial site. A Site Assessment plan submitted to the State of Iowa Department of Natural Resources (DNR) was approved. A Remedial Investigation/Feasibility Study work plan has been completed for additional studies at the site. This has been reviewed and approved by the DOE Chicago Field Office and the DNR. A National Environmental Policy Act (NEPA) review of the site resulted in a categorical exclusion finding which has been approved by the DOE. Ames Laboratory has an area contaminated by diesel fuel at the location of a storage tank which was removed in 1970. Soil corings and groundwater have been analyzed for contamination and an assessment written. Pollution awareness and waste minimization programs and plans were implemented in 1990. Included in this effort was the implementation of a waste white paper and green computer paper recycling program

Is the Moon Illusion a Celestial Ames Demonstration?

Science.gov (United States)

Brecher, Kenneth

2010-01-01

To most naked eye observers, the Moon appears larger when seen near the horizon than it does when seen near the zenith. This "Moon Illusion” has been reported from as early as the fourth century BC and has been the subject of hundreds of papers and two books. Its explanation does not lie in the realm of physics (atmospheric refraction) or astronomy (eccentric lunar orbit) but, rather, in the realm of visual perception. Theories for the cause of the effect abound but, at present, there is no universally accepted explanation. Because the effect can be easily observed in many locations and during the course of an academic year, the moon illusion can provide a nice astronomical example that involves both direct observations and theoretical analysis. As part of the NSF funded "Project LITE: Light Inquiry Through Experiments", we have been developing inexpensive experiments and demonstrations that can be done at home. One of these is a miniature version of the classic "Ames Room". The life size version was originally developed by Adelbert Ames, Jr. and can be seen in many science museums. Our "digital” Ames Room has been designed to be printed on heavy paper using an inexpensive inkjet printer from a PDF file that is posted on the Project LITE web site http://lite.bu.edu and then cut and folded to make the room. When viewed through one wall using a commonly available door viewer, it dramatically demonstrates how the eye and brain system assesses the relative size of objects by making comparisons with the surrounding environment in which the objects are placed. In this presentation we will discuss some insights that the Ames Room provides that may offer clues to the correct explanation for the Moon Illusion. Project LITE is supported by the NSF through DUE Grant # 0715975.

Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice.

Science.gov (United States)

Csiszar, Anna; Labinskyy, Nazar; Perez, Viviana; Recchia, Fabio A; Podlutsky, Andrej; Mukhopadhyay, Partha; Losonczy, Gyorgy; Pacher, Pal; Austad, Steven N; Bartke, Andrzej; Ungvari, Zoltan

2008-11-01

Hypopituitary Ames dwarf mice have low circulating growth hormone (GH)/IGF-I levels, and they have extended longevity and exhibit many symptoms of delayed aging. To elucidate the vascular consequences of Ames dwarfism we compared endothelial O2(-) and H2O2 production, mitochondrial reactive oxygen species (ROS) generation, expression of antioxidant enzymes, and nitric oxide (NO) production in aortas of Ames dwarf and wild-type control mice. In Ames dwarf aortas endothelial O2(-) and H2O2 production and ROS generation by mitochondria were enhanced compared with those in vessels of wild-type mice. In Ames dwarf aortas there was a less abundant expression of Mn-SOD, Cu,Zn-SOD, glutathione peroxidase (GPx)-1, and endothelial nitric oxide synthase (eNOS). NO production and acetylcholine-induced relaxation were also decreased in aortas of Ames dwarf mice. In cultured wild-type mouse aortas and in human coronary arterial endothelial cells treatment with GH and IGF significantly reduced cellular O2(-) and H2O2 production and ROS generation by mitochondria and upregulated expression of Mn-SOD, Cu,Zn-SOD, GPx-1, and eNOS. Thus GH and IGF-I promote antioxidant phenotypic changes in the endothelial cells, whereas Ames dwarfism leads to vascular oxidative stress.

Ames Laboratory Site Environmental Report, Calendar year 1992

International Nuclear Information System (INIS)

1992-01-01

The summarized data and conclusions from the Ames Laboratory environmental monitoring program are presented in this Annual Site Environmental Report. Pollution awareness and waste minimization programs and plans implemented in 1990 are continuing to date. Ames Laboratory (AL) is responsible for a small chemical burial site, located on ISU property. The site was used for the disposal of chemical and metal slags from thorium and uranium production. Samples of water from existing test wells, and upstream and downstream sites on the nearby Squaw Creek, have not detected migration of the buried materials off site. Surface, hand auger and deep boring soil samples have been collected from the site. The analytical results are pending, Six new monitoring wells have been installed and sampled. Analytical results are pending. Ames Laboratory is responsible for an area contaminated by diesel fuel that leaked from an underground storage tank (UST) in 1970. The tank was removed that year. Soil borings and groundwater have been analyzed for contamination and a preliminary assessment written. Nine small inactive waste sites have been identified for characterization. The NEPA review for this work resulted in a CX determination. The work plans were approved by AL and CH. A subcontractor has surveyed and sampled the sites. Analytical results are pending

Phospholipid composition and longevity: lessons from Ames dwarf mice.

Science.gov (United States)

Valencak, Teresa G; Ruf, Thomas

2013-12-01

Membrane fatty acid (FA) composition is correlated with longevity in mammals. The "membrane pacemaker hypothesis of ageing" proposes that animals which cellular membranes contain high amounts of polyunsaturated FAs (PUFAs) have shorter life spans because their membranes are more susceptible to peroxidation and further oxidative damage. It remains to be shown, however, that long-lived phenotypes such as the Ames dwarf mouse have membranes containing fewer PUFAs and thus being less prone to peroxidation, as would be predicted from the membrane pacemaker hypothesis of ageing. Here, we show that across four different tissues, i.e., muscle, heart, liver and brain as well as in liver mitochondria, Ames dwarf mice possess membrane phospholipids containing between 30 and 60 % PUFAs (depending on the tissue), which is similar to PUFA contents of their normal-sized, short-lived siblings. However, we found that that Ames dwarf mice membrane phospholipids were significantly poorer in n-3 PUFAs. While lack of a difference in PUFA contents is contradicting the membrane pacemaker hypothesis, the lower n-3 PUFAs content in the long-lived mice provides some support for the membrane pacemaker hypothesis of ageing, as n-3 PUFAs comprise those FAs being blamed most for causing oxidative damage. By comparing tissue composition between 1-, 2- and 6-month-old mice in both phenotypes, we found that membranes differed both in quantity of PUFAs and in the prevalence of certain PUFAs. In sum, membrane composition in the Ames dwarf mouse supports the concept that tissue FA composition is related to longevity.

NASA Ames Fluid Mechanics Laboratory research briefs

Science.gov (United States)

Davis, Sanford (Editor)

1994-01-01

The Ames Fluid Mechanics Laboratory research program is presented in a series of research briefs. Nineteen projects covering aeronautical fluid mechanics and related areas are discussed and augmented with the publication and presentation output of the Branch for the period 1990-1993.

The Ame2012 atomic mass evaluation. Pt. 1. Evaluation of input data, adjustment procedures

International Nuclear Information System (INIS)

Audi, G; Wang, M.; Wapstra, A.H.; Kondev, F.G.; MacCormick, M.; Xu, X.; Pfeiffer, B.

2012-01-01

This paper is the first of two articles (Part I and Part II) that presents the results of the new atomic mass evaluation, Ame2012. It includes complete information on the experimental input data (including not used and rejected ones), as well as details on the evaluation procedures used to derive the tables with recommended values given in the second part. This article describes the evaluation philosophy and procedures that were implemented in the selection of specific nuclear reaction, decay and mass-spectrometer results. These input values were entered in the least-squares adjustment procedure for determining the best values for the atomic masses and their uncertainties. Calculation procedures and particularities of the AME are then described. All accepted and rejected data, including outweighed ones, are presented in a tabular format and compared with the adjusted values (obtained using the adjustment procedure). Differences with the previous Ame2003 evaluation are also discussed and specific information is presented for several cases that may be of interest to various AME users. The second Ame2012 article, the last one in this issue, gives a table with recommended values of atomic masses, as well as tables and graphs of derived quantities, along with the list of references used in both this Ame2012 evaluation and the Nubase2012 one (the first paper in this issue). (authors)

Ames Laboratory annual site environmental report, calendar year 1996

International Nuclear Information System (INIS)

1998-04-01

This report summarizes the environmental status of Ames Laboratory for calendar year 1996. It includes descriptions of the Laboratory site, its mission, the status of its compliance with applicable environmental regulations, its planning and activities to maintain compliance, and a comprehensive review of its environmental protection, surveillance and monitoring programs. Ames Laboratory is located on the campus of Iowa State University (ISU) and occupies twelve buildings owned by the Department of Energy (DOE). The Laboratory also leases space in ISU owned buildings. Laboratory activities involve less than ten percent of the total chemical use and approximately one percent of the radioisotope use on the ISU campus. In 1996, the Office of Assurance and Assessment merged with the Environment, Safety and Health Group forming the Environment, Safety, Health and Assurance (ESH and A) office. In 1996, the Laboratory accumulated and disposed of wastes under US Environmental Protection Agency (EPA) issued generator numbers. Ames Laboratory submitted a Proposed Site Treatment Plan to EPA in December 1995. This plan complied with the Federal Facilities Compliance Act (FFCA). It was approved by EPA in January 1996. The consent agreement/consent order was issued in February 1996. Pollution awareness, waste minimization and recycling programs, implemented in 1990 and updated in 1994, continued through 1996. Included in these efforts were a waste white paper and green computer paper recycling program. Ames Laboratory also continued to recycle salvageable metal and used oil, and it recovered freon for recycling. All of the chemical and nearly all of the radiological legacy wastes were properly disposed by the end of 1996. Additional radiological legacy waste will be properly disposed during 1997

(New) NASA Director Sean O'Keefe comes to Ames for employee briefing and tour. Meets with Roberto

Science.gov (United States)

2002-01-01

(New) NASA Director Sean O'Keefe comes to Ames for employee briefing and tour. Meets with Roberto Cruz, National Hispanic University (seated, right) and Ames Center Director Dr. Henry McDonald follow the signing of the educational MOU between NHU and Ames.

The Ame2012 atomic mass evaluation. Pt. 2. Tables, graphs and references

International Nuclear Information System (INIS)

Wang, M.; Audi, G.; Wapstra, A.H.; Kondev, F.G.; MacCormick, M.; Xu, X.; Pfeiffer, B.

2012-01-01

This paper is the second part of the new evaluation of atomic masses, Ame2012. From the results of a least-squares calculation, described in Part I, for all accepted experimental data, we derive here tables and graphs to replace those of Ame2003. The first table lists atomic masses. It is followed by a table of the influences of data on primary nuclides, a table of separation energies and reaction energies, and finally, a series of graphs of separation and decay energies. The last section in this paper lists all references to the input data used in Part I of this Ame2012 and also to the data included in the Nubase2012 evaluation (first paper in this issue). (authors)

Analysis of Hexanitrostilbene (HNS) and Dipicryethane (DPE) for Mutagenicity by the Ames/Salmonella Assay

Energy Technology Data Exchange (ETDEWEB)

Wu, R; Felton, J

2007-10-12

The Ames/Salmonella assay, developed by Professor Bruce Ames at the University of California, Berkeley, is a rapid and sensitive assay for detecting mutagenicity of various chemical compounds (Maron and Ames, 1983). It is a widely accepted short-term assay for detecting chemicals that induce mutations in the histidine (his) gene of Salmonella typhimurium. This is a reverse mutation assay that detects the mutational reversion of his-dependent Salmonella to the his-independent counterpart. Thereby, mutagenic compounds will increase the frequency of occurrence of his-independent bacterial colonies. The assay utilizes the specific genetically constructed strains of bacteria either with or without mammalian metabolic activation enzymes (S9), Aroclor induced rat liver homogenate to assess the mutagenicity of different compounds. In this study, we will use the Ames/Salmonella assay to investigate the mutagenicity of Hexanitrostilbene (HNS) from both Bofors and Pantex, and Dipicryethane (DPE).

A non-randomized [corrected] controlled trial of the active music engagement (AME) intervention on children with cancer.

Science.gov (United States)

Robb, Sheri L; Clair, Alicia A; Watanabe, Masayo; Monahan, Patrick O; Azzouz, Faouzi; Stouffer, Janice W; Ebberts, Allison; Darsie, Emily; Whitmer, Courtney; Walker, Joey; Nelson, Kirsten; Hanson-Abromeit, Deanna; Lane, Deforia; Hannan, Ann

2008-07-01

Coping theorists argue that environmental factors affect how children perceive and respond to stressful events such as cancer. However, few studies have investigated how particular interventions can change coping behaviors. The active music engagement (AME) intervention was designed to counter stressful qualities of the in-patient hospital environment by introducing three forms of environmental support. The purpose of this multi-site randomized controlled trial was to determine the efficacy of the AME intervention on three coping-related behaviors (i.e. positive facial affect, active engagement, and initiation). Eighty-three participants, ages 4-7, were randomly assigned to one of three conditions: AME (n = 27), music listening (ML; n = 28), or audio storybooks (ASB; n = 28). Conditions were videotaped to facilitate behavioral data collection using time-sampling procedures. After adjusting for baseline differences, repeated measure analyses indicated that AME participants had a significantly higher frequency of coping-related behaviors compared with ML or ASB. Positive facial affect and active engagement were significantly higher during AME compared with ML and ASB (p<0.0001). Initiation was significantly higher during AME than ASB (p<0.05). This study supports the use of the AME intervention to encourage coping-related behaviors in hospitalized children aged 4-7 receiving cancer treatment. (c) 2007 John Wiley & Sons, Ltd.

Ames hypopituitary dwarf mice demonstrate imbalanced myelopoiesis between bone marrow and spleen.

Science.gov (United States)

Capitano, Maegan L; Chitteti, Brahmananda R; Cooper, Scott; Srour, Edward F; Bartke, Andrzej; Broxmeyer, Hal E

2015-06-01

Ames hypopituitary dwarf mice are deficient in growth hormone, thyroid-stimulating hormone, and prolactin. The phenotype of these mice demonstrates irregularities in the immune system with skewing of the normal cytokine milieu towards a more anti-inflammatory environment. However, the hematopoietic stem and progenitor cell composition of the bone marrow (BM) and spleen in Ames dwarf mice has not been well characterized. We found that there was a significant decrease in overall cell count when comparing the BM and spleen of 4-5 month old dwarf mice to their littermate controls. Upon adjusting counts to differences in body weight between the dwarf and control mice, the number of granulocyte-macrophage progenitors, confirmed by immunophenotyping and colony-formation assay was increased in the BM. In contrast, the numbers of all myeloid progenitor populations in the spleen were greatly reduced, as confirmed by colony-formation assays. This suggests that there is a shift of myelopoiesis from the spleen to the BM of Ames dwarf mice; however, this shift does not appear to involve erythropoiesis. The reasons for this unusual shift in spleen to marrow hematopoiesis in Ames dwarf mice are yet to be determined but may relate to the decreased hormone levels in these mice. Copyright © 2015. Published by Elsevier Inc.

2-Hydroxypyridine-N-oxide (HOPO): Equivocal in the ames assay.

Science.gov (United States)

Dobo, Krista L; Cheung, Jennifer R; Gunther, William C; Kenyon, Michelle O

2018-05-01

2-Hydroxypyridine-N-oxide (HOPO) is a useful coupling reagent for synthesis of active pharmaceutical ingredients. It has been reported to be weakly mutagenic in the Ames assay (Ding W et al. []: J Chromatogr A 1386:47-52). According to the ICH M7 guidance (2014) regarding control of mutagenic impurities to limit potential carcinogenic risk, mutagens require control in drug substances such that exposure not exceeds the threshold of toxicological concern. Given the weak response observed in the Ames assay and the lack of any obvious structural features that could confer DNA reactivity we were interested to determine if the results were reproducible and investigate the role of potentially confounding experimental parameters. Specifically, Ames tests were conducted to assess the influence of compound purity, solvent choice, dose spacing, toxicity, type of S9 (aroclor vs phenobarbital/β-napthoflavone), and lot variability on the frequency of HOPO induced revertant colonies. Initial extensive testing using one lot of HOPO produced no evidence of mutagenic potential in the Ames assays. Subsequent studies with four additional lots produced conflicting results, with an ∼2.0-fold increase in revertant colonies observed. Given the rigor of the current investigation, lack of reproducibility between lots, and the weak increase in revertants, it is concluded that HOPO is equivocal in the bacterial reverse mutation assay. It is highly unlikely that HOPO poses a mutagenic risk in vivo; therefore, when it is used as a reagent in pharmaceutical synthesis, it should not be regarded as a mutagenic impurity, but rather a normal process related impurity. Environ. Mol. Mutagen. 59:312-321, 2018. © 2018 Wiley Periodicals, Inc. © 2018 Wiley Periodicals, Inc.

Ames and other European networks in integrity of ageing structures

International Nuclear Information System (INIS)

Davies, L.M.; Von Estorff, U.; Crutzen, S.

1996-01-01

Several European institutions and organisations and the Joint Research Centre have developed co-operative programmes now organised into Networks for mutual benefit. They include utilities, engineering companies, Research and Development laboratories and regulatory bodies. Networks are organised and managed like the successful Programme for the Inspection of Steel Components (PISC). The JRC's Institute for Advanced Materials of the European Commission plays the role of Operating Agent and manager of these Networks: ENIQ. AMES, NESC, each of them dealing with specific aspect of fitness for purpose of materials in structural components. This paper describes the structure and the objectives of these networks. Particular emphasis is given to the network AMES

The AME2003 atomic mass evaluation (I). Evaluation of input data, adjustment procedures

International Nuclear Information System (INIS)

Wapstra, A.H.; Audi, G.; Thibault, C.

2003-01-01

This paper is the first of two parts presenting the result of a new evaluation of atomic masses (AME2003). In this first part we give full information on the used and rejected input data and on the procedures used in deriving the tables in the second part. We first describe the philosophy and procedures used in selecting nuclear-reaction, decay, and mass spectrometric results as input values in a least-squares evaluation of best values for atomic masses. The calculation procedures and particularities of the AME are then described. All accepted data, and rejected ones with a reported precision still of interest, are presented in a table and compared there with the adjusted values. The differences with the earlier evaluation are briefly discussed and information is given of interest for the users of this AME. The second paper for the AME2003, last in this issue, gives a table of atomic masses, tables and graphs of derived quantities, and the list of references used in both this evaluation and the NUBASE2003 table (first paper in this issue). AMDC: http://csnwww.in2p3.fr/AMDC/

(New) NASA Administrator Sean O'Keefe comes to Ames for employee briefing and tour. Meets with

Science.gov (United States)

2002-01-01

(New) NASA Administrator Sean O'Keefe comes to Ames for employee briefing and tour. Meets with Roberto Cruz, National Hispanic University (left) at Amesto sign the educational MOU between NHU and Ames.

The AMES network strategy developments within and outside the EU

International Nuclear Information System (INIS)

Sevini, F.; Debarberis, L.; Davies, L.M.; English, C.

2001-01-01

The AMES (Ageing Materials Evaluation and Studies) network started its activity in 1993 with the aim of studying the consequences and the mechanisms of the ageing process in materials used for nuclear reactor components. Together with ENIQ, NESC, EPERC, it forms the so-called ''Structural Integrity of Industrial Components'' cluster of networks operated by the Joint Research Centre - Institute for Advanced Materials of the European Commission. After two initial phases dedicated to the compilation of state-of-the-art reports on non-destructive monitoring techniques for thermal ageing, dosimetry, survey of regulatory requirements, predictive formulas for irradiation embrittlement, AMES has entered its third strategy phase with the fifth EURATOM Framework Program, Nuclear Fission Safety Key Action. Most of the projects proposed for this program and sustained by the Steering committee were selected for funding. Their focus is on the influence of chemical composition, namely phosphorus and nickel content, on the irradiation embrittlement of reactor pressure vessel materials, on the improvement of surveillance temperature measurement, on the validation of the Master Curve approach, and on ND techniques to monitor ageing of irradiated steels. The paper describes the objectives of the new fifth Framework Program projects and how they are part of the AMES strategy, pointing out the involvement of CEEC and NIS countries. (authors)

A Survey of Knowledge Management Research & Development at NASA Ames Research Center

Science.gov (United States)

Keller, Richard M.; Clancy, Daniel (Technical Monitor)

2002-01-01

This chapter catalogs knowledge management research and development activities at NASA Ames Research Center as of April 2002. A general categorization scheme for knowledge management systems is first introduced. This categorization scheme divides knowledge management capabilities into five broad categories: knowledge capture, knowledge preservation, knowledge augmentation, knowledge dissemination, and knowledge infrastructure. Each of nearly 30 knowledge management systems developed at Ames is then classified according to this system. Finally, a capsule description of each system is presented along with information on deployment status, funding sources, contact information, and both published and internet-based references.

Expression of oxidative phosphorylation components in mitochondria of long-living Ames dwarf mice.

Science.gov (United States)

Brown-Borg, Holly M; Johnson, W Thomas; Rakoczy, Sharlene G

2012-02-01

Reduced signaling of the growth hormone (GH)/insulin-like growth factor-1 (IGF-1) pathway is associated with extended life span in several species. Ames dwarf mice are GH-deficient and live >50% longer than wild-type littermates. Previously, we have shown that tissues from Ames mice exhibit elevated levels of antioxidative enzymes, less H(2)O(2) production, and lower oxidative damage suggesting that mitochondrial function may differ between genotypes. To explore the relationship between hormone deficiency and mitochondria in mice with extended longevity, we evaluated activity, protein, and gene expression of oxidative phosphorylation components in dwarf and wild-type mice at varying ages. Liver complex I + III activity was higher in dwarf mice compared to wild-type mice. The activity of I + III decreased between 3 and 20 months of age in both genotypes with greater declines in wild-type mice in liver and skeletal muscle. Complex IV activities in the kidney were elevated in 3- and 20-month-old dwarf mice relative to wild-type mice. In Ames mice, protein levels of the 39 kDa complex I subunit were elevated at 20 months of age when compared to wild-type mouse mitochondria for every tissue examined. Kidney and liver mitochondria from 20-month-old dwarf mice had elevated levels of both mitochondrially-encoded and nuclear-encoded complex IV proteins compared to wild-type mice (p dwarf mice. Overall, we found that several components of the oxidative phosphorylation (OXPHOS) system were elevated in Ames mice. Mitochondrial to nuclear DNA ratios were not different between genotypes despite the marked increase in PGC-1α levels in dwarf mice. The increased OXPHOS activities, along with lower ROS production in dwarf mice, predict enhanced mitochondrial function and efficiency, two factors likely contributing to long-life in Ames mice.

Developing questionnaires for educational research: AMEE Guide No. 87

Science.gov (United States)

La Rochelle, Jeffrey S.; Dezee, Kent J.; Gehlbach, Hunter

2014-01-01

In this AMEE Guide, we consider the design and development of self-administered surveys, commonly called questionnaires. Questionnaires are widely employed in medical education research. Unfortunately, the processes used to develop such questionnaires vary in quality and lack consistent, rigorous standards. Consequently, the quality of the questionnaires used in medical education research is highly variable. To address this problem, this AMEE Guide presents a systematic, seven-step process for designing high-quality questionnaires, with particular emphasis on developing survey scales. These seven steps do not address all aspects of survey design, nor do they represent the only way to develop a high-quality questionnaire. Instead, these steps synthesize multiple survey design techniques and organize them into a cohesive process for questionnaire developers of all levels. Addressing each of these steps systematically will improve the probabilities that survey designers will accurately measure what they intend to measure. PMID:24661014

Unique life sciences research facilities at NASA Ames Research Center

Science.gov (United States)

Mulenburg, G. M.; Vasques, M.; Caldwell, W. F.; Tucker, J.

1994-01-01

The Life Science Division at NASA's Ames Research Center has a suite of specialized facilities that enable scientists to study the effects of gravity on living systems. This paper describes some of these facilities and their use in research. Seven centrifuges, each with its own unique abilities, allow testing of a variety of parameters on test subjects ranging from single cells through hardware to humans. The Vestibular Research Facility allows the study of both centrifugation and linear acceleration on animals and humans. The Biocomputation Center uses computers for 3D reconstruction of physiological systems, and interactive research tools for virtual reality modeling. Psycophysiological, cardiovascular, exercise physiology, and biomechanical studies are conducted in the 12 bed Human Research Facility and samples are analyzed in the certified Central Clinical Laboratory and other laboratories at Ames. Human bedrest, water immersion and lower body negative pressure equipment are also available to study physiological changes associated with weightlessness. These and other weightlessness models are used in specialized laboratories for the study of basic physiological mechanisms, metabolism and cell biology. Visual-motor performance, perception, and adaptation are studied using ground-based models as well as short term weightlessness experiments (parabolic flights). The unique combination of Life Science research facilities, laboratories, and equipment at Ames Research Center are described in detail in relation to their research contributions.

Mixing alcohol with energy drink (AMED) and total alcohol consumption : a systematic review and meta-analysis

NARCIS (Netherlands)

Verster, Joris C|info:eu-repo/dai/nl/241442702; Benson, Sarah; Johnson, Sean J; Scholey, Andrew; Alford, Chris

It has been suggested that consuming alcohol mixed with energy drink (AMED) may increase total alcohol consumption. Aims of this systematic review and meta-analysis were (i) to compare alcohol consumption of AMED consumers with alcohol only (AO) consumers (between-group comparisons), and (ii) to

The microRNA ame-miR-279a regulates sucrose responsiveness of forager honey bees (Apis mellifera).

Science.gov (United States)

Liu, Fang; Shi, Tengfei; Yin, Wei; Su, Xin; Qi, Lei; Huang, Zachary Y; Zhang, Shaowu; Yu, Linsheng

2017-11-01

Increasing evidence demonstrates that microRNAs (miRNA) play an important role in the regulation of animal behaviours. Honey bees (Apis mellifera) are eusocial insects, with honey bee workers displaying age-dependent behavioural maturation. Many different miRNAs have been implicated in the change of behaviours in honey bees and ame-miR-279a was previously shown to be more highly expressed in nurse bee heads than in those of foragers. However, it was not clear whether this difference in expression was associated with age or task performance. Here we show that ame-miR-279a shows significantly higher expression in the brains of nurse bees relative to forager bees regardless of their ages, and that ame-miR-279a is primarily localized in the Kenyon cells of the mushroom body in both foragers and nurses. Overexpression of ame-miR-279a attenuates the sucrose responsiveness of foragers, while its absence enhances their sucrose responsiveness. Lastly, we determined that ame-miR-279a directly target the mRNA of Mblk-1. These findings suggest that ame-miR-279a plays important roles in regulating honey bee division of labour. Copyright © 2017 Elsevier Ltd. All rights reserved.

Aerial radiological survey of US Department of Energy sites in Ames, Iowa. Date of survey: May 1977

International Nuclear Information System (INIS)

1979-07-01

An aerial radiological survey to measure terrestrial gamma radiation was carried out over five areas totaling 10 km 2 within the town of Ames, Iowa. Gamma ray data were measured over Ames Laboratory, several sections of downtown Ames, and the surrounding area. This was accomplished by flying parallel east-west lines 61 m apart. Processed data indicated that three areas showed increased activity levels of at least twice average background: the reactor, the waste treatment area, and a small area near the airport runway

(New) NASA Administrator Sean O'Keefe comes to Ames for employee briefing and tour. Here he welcomes

Science.gov (United States)

2002-01-01

(New) NASA Administrator Sean O'Keefe comes to Ames for employee briefing and tour. Here he welcomes JASON kids to NASA while handing out patches and pins. Tom Clausen and Donald James, Ames Education Office in background.

Resolution of contradiction between in silico predictions and Ames test results for four pharmaceutically relevant impurities.

Science.gov (United States)

Gunther, William C; Kenyon, Michelle O; Cheung, Jennifer R; Dugger, Robert W; Dobo, Krista L

2017-12-01

The ICH M7 Guideline requires low level control of mutagenic impurities in pharmaceutical products to minimize cancer risk in patients (ICHM7, 2014). Bacterial mutagenicity (Ames) data is generally used to determine mutagenic and possible carcinogenic potential of compounds. Recently, a publication on experiences of using two in silico systems to identify potentially mutagenic impurities highlighted the importance of performing a critical review of published Ames data utilized as part of a mutagenicity assessment of impurities (Greene et al., 2015). Four compounds (2-amino-5-hydroxybenzoic acid, 2-amino-3-chlorobenzoic acid, methyl 2-amino-4-chlorobenzoate and 4-morpholinopyridine) reported mutagenic were identified in a two system in silico assessment and expert review of the structuresas non-mutagenic. Likely reasons for mutagenicity could not be identified and the purity of the compounds tested was proposed. In the current investigation, the purest available sample of the four compounds was tested in an OECD-compliant Ames test. The compounds were all found to be non-mutagenic. Possible reasons for the discrepancy between previously reported and current results are discussed. Additionally, important points to consider when conducting an expert review of available Ames data are provided particularly in cases where reported Ames results are discrepant with a two system in silico assessment. Copyright © 2017 Elsevier Inc. All rights reserved.

NASA Ames Arc Jets and Range, Capabilities for Planetary Entry

Science.gov (United States)

Fretter, Ernest F.

2005-01-01

NASA is pursuing innovative technologies and concepts as part of America's Vision for Space Exploration. The rapidly emerging field of nanotechnology has led to new concepts for multipurpose shields to prevent catastrophic loss of vehicles and crew against the triple threats of aeroheating during atmospheric entry, radiation (Solar and galactic cosmic rays) and Micrometorid/Orbital Debris (MMOD) strikes. One proposed concept is the Thermal Radiation Impact Protection System (TRIPS) using carbon nanotubes, hydrogenated carbon nanotubes, and ceramic coatings as a multi-use TPS. The Thermophysics Facilities Branch of the Space Technology Division at NASA Ames Research Center provides testing services for the development and validation of the present and future concepts being developed by NASA and national and International research firms. The Branch operates two key facilities - the Range Complex and the Arc Jets. The Ranges include both the Ames Vertical Gun Range (AVGR) and the Hypervelocity Free Flight (HFF) gas guns best suited for MMOD investigations. Test coupons can be installed in the AVGR or HFF and subjected to particle impacts from glass or metal particles from micron to _ inch (6.35-mm) diameters and at velocities from 5 to 8 kilometers per second. The facility can record high-speed data on film and provide damage assessment for analysis by the Principle Investigator or Ames personnel. Damaged articles can be installed in the Arc Jet facility for further testing to quantify the effects of damage on the heat shield s performance upon entry into atmospheric environments.

Groundwater hydrology study of the Ames Chemical Disposal Site

International Nuclear Information System (INIS)

Stickel, T.

1996-01-01

The Ames Laboratory Chemical Disposal Site is located in northwestern Ames, Iowa west of Squaw Creek. From 1957 to 1966, Ames Laboratory conducted research to develop processes to separate uranium and thorium from nuclear power fuel and to separate yttrium from neutron shielding sources. The wastes from these processes, which contained both hazardous and radiological components, were placed into nine burial pits. Metal drums, plywood boxes, and steel pails were used to store the wastes. Uranium was also burned on the ground surface of the site. Monitoring wells were placed around the waste burial pits. Groundwater testing in 1993 revealed elevated levels of Uranium 234, Uranium 238, beta and alpha radiation. The north side of the burial pit had elevated levels of volatile organic compounds. Samples in the East Ravine showed no volatile organics; however, they did contain elevated levels of radionuclides. These analytical results seem to indicate that the groundwater from the burial pit is flowing down hill and causing contamination in the East Ravine. Although there are many avenues for the contamination to spread, the focus of this project is to understand the hydrogeology of the East Ravine and to determine the path of groundwater flow down the East Ravine. The groundwater flow data along with other existing information will be used to assess the threat of chemical migration down the East Ravine and eventually off-site. The primary objectives of the project were as follows: define the geology of the East Ravine; conduct slug tests to determine the hydraulic conductivity of both oxidized and unoxidized till; develop a three-dimensional mathematical model using ModIME and MODFLOW to simulate groundwater flow in the East Ravine

NMDA and kainate receptor expression, long-term potentiation, and neurogenesis in the hippocampus of long-lived Ames dwarf mice.

Science.gov (United States)

Sharma, Sunita; Darland, Diane; Lei, Saobo; Rakoczy, Sharlene; Brown-Borg, Holly M

2012-06-01

In the current study, we investigated changes in N-methyl D-aspartate (NMDA) and kainate receptor expression, long-term potentiation (LTP), and neurogenesis in response to neurotoxic stress in long-living Ames dwarf mice. We hypothesized that Ames dwarf mice have enhanced neurogenesis that enables retention of spatial learning and memory with age and promotes neurogenesis in response to injury. Levels of the NMDA receptors (NR)1, NR2A, NR2B, and the kainate receptor (KAR)2 were increased in Ames dwarf mice, relative to wild-type littermates. Quantitative assessment of the excitatory postsynaptic potential in Schaffer collaterals in hippocampal slices from Ames dwarf mice showed an increased response in high-frequency induced LTP over time compared with wild type. Kainic acid (KA) injection was used to promote neurotoxic stress-induced neurogenesis. KA mildly increased the number of doublecortin-positive neurons in wild-type mice, but the response was significantly enhanced in the Ames dwarf mice. Collectively, these data support our hypothesis that the enhanced learning and memory associated with the Ames dwarf mouse may be due to elevated levels of NMDA and KA receptors in hippocampus and their ability to continue producing new neurons in response to neuronal damage.

Corrective Action Plan in response to the March 1992 Tiger Team Assessment of the Ames Laboratory

International Nuclear Information System (INIS)

1992-01-01

On March 5, 1992, a Department of Energy (DOE) Tiger Team completed an assessment of the Ames Laboratory, located in Ames, Iowa. The purpose of the assessment was to provide the Secretary of Energy with a report on the status and performance of Environment, Safety and Health (ES ampersand H) programs at Ames Laboratory. Detailed findings of the assessment are presented in the report, DOE/EH-0237, Tiger Team Assessment of the Ames Laboratory. This document, the Ames Laboratory Corrective Action Plan (ALCAP), presents corrective actions to overcome deficiencies cited in the Tiger Team Assessment. The Tiger Team identified 53 Environmental findings, from which the Team derived four key findings. In the Safety and Health (S ampersand H) area, 126 concerns were identified, eight of which were designated Category 11 (there were no Category I concerns). Seven key concerns were derived from the 126 concerns. The Management Subteam developed 19 findings which have been summarized in four key findings. The eight S ampersand H Category 11 concerns identified in the Tiger Team Assessment were given prompt management attention. Actions to address these deficiencies have been described in individual corrective action plans, which were submitted to DOE Headquarters on March 20, 1992. The ALCAP includes actions described in this early response, as well as a long term strategy and framework for correcting all remaining deficiencies. Accordingly, the ALCAP presents the organizational structure, management systems, and specific responses that are being developed to implement corrective actions and to resolve root causes identified in the Tiger Team Assessment. The Chicago Field Office (CH), IowaState University (ISU), the Institute for Physical Research and Technology (IPRT), and Ames Laboratory prepared the ALCAP with input from the DOE Headquarters, Office of Energy Research (ER)

NASA Ames DEVELOP Interns: Helping the Western United States Manage Natural Resources One Project at a Time

Science.gov (United States)

Justice, Erin; Newcomer, Michelle

2010-01-01

The western half of the United States is made up of a number of diverse ecosystems ranging from arid desert to coastal wetlands and rugged forests. Every summer for the past 7 years students ranging from high school to graduate level gather at NASA Ames Research Center (ARC) as part of the DEVELOP Internship Program. Under the guidance of Jay Skiles [Ames Research Center (ARC) - Ames DEVELOP Manager] and Cindy Schmidt [ARC/San Jose State University Ames DEVELOP Coordinator] they work as a team on projects exploring topics including: invasive species, carbon flux, wetland restoration, air quality monitoring, storm visualizations, and forest fires. The study areas for these projects have been in Washington, Utah, Oregon, Nevada, Hawaii, Alaska and California. Interns combine data from NASA and partner satellites with models and in situ measurements to complete prototype projects demonstrating how NASA data and resources can help communities tackle their Earth Science related problems.

Long-lived ames dwarf mice are resistant to chemical stressors.

Science.gov (United States)

Bokov, Alex F; Lindsey, Merry L; Khodr, Christina; Sabia, Marian R; Richardson, Arlan

2009-08-01

To probe the connection between longevity and stress resistance, we compared the sensitivity of Ames long-lived dwarf mice and control littermates with paraquat, diquat, and dobutamine. In young adult animals, 95% of male and 39% of female controls died after paraquat administration, but no dwarf animals died. When the experiment was repeated at an older age or a higher dosage of paraquat, dwarf mice still showed greater resistance. Dwarf mice also were more resistant to diquat; 80% of male and 60% of female controls died compared with 40% and 20% of dwarf mice, despite greater sensitivity of dwarf liver to diquat. Dwarf mice were also less sensitive to dobutamine-induced cardiac stress and had lower levels of liver and lung F(2)-isoprostanes. This is the first direct in vivo evidence that long-lived Ames dwarf mice have enhanced resistance to chemical insult, particularly oxidative stressors.

Collective effects in Au(100-800 AMeV) + Au semi-central collisions; Effets collectifs dans les collisions semi-centrales Au(100-800 AMeV) + Au

Energy Technology Data Exchange (ETDEWEB)

Crochet, P.

1996-04-04

The present work has been carried out in the framework of the experimental program of the FOPI collaboration. It is devoted to a systematic study of the different forms of collective expansion of nuclear matter in semi-central Au+Au collisions at incident energies ranging from 100 AMeV to 800 AMeV. The aim is to investigate the influence of compressional effects, momentum dependence of the nuclear interaction and nucleon-nucleon cross section on the observed phenomena. Important changes in the reaction mechanisms are evidenced, in particular at low incident energies where one observes, on the one hand, a transition from an enhanced in-plane emission to a preferential out-of-plane emission pattern and, on the other hand, a strong reduction of the directed in-plane component. Experimental results are compared to the predictions of the Quantum Molecular Dynamics (QMD) model for different parametrizations of the nuclear interaction. (author).

Consolidated Laser-Induced Fluorescence Diagnostic Systems for the NASA Ames Arc Jet Facilities

Science.gov (United States)

Grinstead, Jay; Wilder, Michael C.; Porter, Barry; Brown, Jeff; Yeung, Dickson; Battazzo, Steve; Brubaker, Tim

2016-01-01

The spectroscopic diagnostic technique of two photon absorption laser-induced fluorescence (TALIF) of atomic species for non-intrusive arc jet flow property measurement was first implemented at NASA Ames in the mid-1990s. Use of TALIF expanded at NASA Ames and to NASA Johnsons arc jet facility in the late 2000s. In 2013-2014, NASA combined the agency's large-scale arc jet test capabilities at NASA Ames. Concurrent with that effort, the agency also sponsored a project to establish two comprehensive LIF diagnostic systems for the Aerodynamic Heating Facility (AHF) and Interaction Heating Facility (IHF) arc jets. The scope of the project enabled further engineering development of the existing IHF LIF system as well as the complete reconstruction of the original AHF LIF system. The updated LIF systems are identical in design and capability. They represent the culmination of over 20 years of development experience in transitioning a specialized laboratory research tool into a measurement system for large-scale, high-demand test facilities. This paper documents the overall system design from measurement requirements to implementation. Representative data from the redeveloped AHF and IHF LIF systems are also presented.

Air Traffic Management Research at NASA Ames

Science.gov (United States)

Davis, Thomas J.

2012-01-01

The Aviation Systems Division at the NASA Ames Research Center conducts leading edge research in air traffic management concepts and technologies. This overview will present concepts and simulation results for research in traffic flow management, safe and efficient airport surface operations, super density terminal area operations, separation assurance and system wide modeling and simulation. A brief review of the ongoing air traffic management technology demonstration (ATD-1) will also be presented. A panel discussion, with Mr. Davis serving as a panelist, on air traffic research will follow the briefing.

A Perspective on NASA Ames Air Traffic Management Research

Science.gov (United States)

Schroeder, Jeffery A.

2012-01-01

This paper describes past and present air-traffic-management research at NASA Ames Research Center. The descriptions emerge from the perspective of a technical manager who supervised the majority of this research for the last four years. Past research contributions built a foundation for calculating accurate flight trajectories to enable efficient airspace management in time. That foundation led to two predominant research activities that continue to this day - one in automatically separating aircraft and the other in optimizing traffic flows. Today s national airspace uses many of the applications resulting from research at Ames. These applications include the nationwide deployment of the Traffic Management Advisor, new procedures enabling continuous descent arrivals, cooperation with industry to permit more direct flights to downstream way-points, a surface management system in use by two cargo carriers, and software to evaluate how well flights conform to national traffic management initiatives. The paper concludes with suggestions for prioritized research in the upcoming years. These priorities include: enabling more first-look operational evaluations, improving conflict detection and resolution for climbing or descending aircraft, and focusing additional attention on the underpinning safety critical items such as a reliable datalink.

Microplate Ames MPF™ test use in assessment of mutagenic properties of dust pollution

Directory of Open Access Journals (Sweden)

Agnieszka Kozłowska

2012-09-01

Full Text Available Background: Highly industrialized Upper Silesia Region is particularly polluted by both anthropogenic and natural airborne particulate matters, which may lead to negative health effects in human. Materials and methods: The aim of the study was to assess the mutagenic properties of dust extracts which were collected in six cities in the Silesian Voivodeship. Dust samples were collected on glass fiber filters by the aspirator with air flow ca. 1 m3/min. Extraction of pollution was carried out using dichlorometane. The extracted samples were dissolved in dimethylsulfoxide (DMSO. The mutagenic properties were assessed using microplate Ames assay MPFTM with the use of bacteria Salmonella typhimurium strain TA98 and TA100. Results: In microplate Ames assay MPFTM there was observed a linear dose-response relationship in both metabolic variants of TA98 strain. Similar relationship was observed for TA100 strain with metabolic activation (S9. Mutagenic activity (AM of 100% extracts for TA98 strain in both metabolic variants (S9 exceeded 2, what indicate highly mutagenic effects of dust extracts. There was no mutagenic activity observed in the assay with TA100 (S9, AM 1. In the variant with exogenous metabolic activation (S9 in TA100 strain AM values ranged from AM1,160,15 to AM9,671,02. Mutagenic activity varied between different cities. Conclusions: The study demonstrated that microplate Ames assay MPFTM is fast and complex method of assessing the mutagenic properties of dust pollution, which exert toxic effect on organisms. The use of microplate Ames assay MPFTM together with chemical analyses of air dust pollution may evaluate the level of exposure in the environment and enable to perform health risk assessment in populations exposed to mutagenic, toxic and cytotoxic substances.

LYRA and other projects on RPV steel embrittlement study and mitigation of the AMES network

International Nuclear Information System (INIS)

Debarberis, L.; Estorff, U. von; Crutzen, S.; Beers, M.; Stamm, H.; Vries, M.I. de; Tjoa, G.L.

1998-01-01

Within the framework of the European Network AMES, Ageing Materials evaluation and Studies, a number of experimental works on RPV materials embrittlement are carried out at the Institute of Advanced Materials (AIM) of the Joint Research Centre (JRC) of the European Commission (EC). The objectives of AMES are mainly the understanding of the property degradation phenomena of RPV western reference steels like JRQ and HSST, eastern RPV steels like 15X2mFA and 15H2X15, and annealing possibilities. In order to conduct a very high quality irradiation rig, LYRA facility, has been designed and developed at the High Flux Reactor (HFR) Petten. An other dedicated rig, named LIMA, has been developed at the HFR Petten in order to irradiate RPV steels, internals and in-core materials under typical BWR/PWR conditions. The samples can be irradiated in pressurised water up to 160 bar, 320 deg. C, and the water chemistry fully controlled. For irradiation of standard or miniaturised LWR related materials samples, another group of well experienced irradiation devices with inert gas or liquid metals environment are employed. These devices are tailored to their various specific applications. This paper is intended to give information about the structure and the objectives of the existing European network AMES, and to present the various AMES main and spin-off projects, including a brief description on he modelling activities related to RPV materials embrittlement. (author)

Use of the modified Ames test as an indicator of the carcinogenicity of residual aromatic extracts

Energy Technology Data Exchange (ETDEWEB)

Boogaard, P.; Hedelin, A.; Riley, A.; Rushton, E.; Vaissiere, M.; Minsavage, G.; Rohde, A.; Dalbey, W.

2013-01-15

Existing data demonstrate that residual aromatic extracts (RAEs) can be either carcinogenic or non-carcinogenic. CONCAWE had previously concluded that 'Although limited data available indicate that some RAEs are weakly carcinogenic, it is not possible to provide a general recommendation. Classify on a case-by-case basis' (CONCAWE 2005). Therefore CONCAWE's Health/Toxicology Subgroup (H/TSG) has developed a proposal for the use of the modified Ames test as a short-term predictive screening tool for decisions on the classification of RAEs for carcinogenicity. The relationship between RAE chemistry and carcinogenic potential is not as well understood as it is for some other categories of substances, e.g. Other Lubricant Base Oils (OLBO). However, a correlation has been found between the results of the skin carcinogenicity bioassay and the mutagenicity index (MI) obtained from the modified Ames test. Data supporting this correlation are summarised in this report. The H/TSG confirmed that the modified Ames test can be used as a predictive screening tool and that a cut-off value can be established to make a distinction between carcinogenic and non-carcinogenic products. RAEs with a MI > 0.4 demonstrated carcinogenic potential upon dermal application to mouse skin with chronic exposure. RAEs with a MI > 0.4 did not demonstrate a carcinogenic potential. To justify the use of the modified Ames test with RAEs, additional analysis of the repeatability of the test with RAEs was required. With this objective, CONCAWE sponsored a round robin study with different samples of RAEs from member companies, at three different laboratories. The repeatability demonstrated in the round robin study with RAEs support the proposed use of the modified Ames test. As part of the tools available for use by member companies, the H/TSG proposed a standard operating procedure (SOP) (included as an Appendix to this report) on the conduct of the modified Ames test with RAEs. The H

Mutagenic activity of a fluorinated analog of the beta-adrenoceptor ligand carazolol in the Ames test

Energy Technology Data Exchange (ETDEWEB)

Doze, P. E-mail: P.Doze@pet.azg.nl; Elsinga, P.H.; Vries, E.F.J. de; Waarde, A. van; Vaalburg, W

2000-04-01

S-1'[{sup 18}F]-Fluorocarazolol (FCAR) is a fluorinated analog of the nonmutagenic beta-blocker carazolol (CAR). In former studies FCAR proved to be suitable for quantification of beta-adrenoceptors in vivo with positron emission tomography (PET). We report here that FCAR displays no acute toxicity in either rats or mice. However, FCAR induces a strong dose-related increase in the number of revertants in the Ames test. We conclude that FCAR yields mutagenic activity as measured by the Ames test.

The NASA Ames Life Sciences Data Archive: Biobanking for the Final Frontier

Science.gov (United States)

Rask, Jon; Chakravarty, Kaushik; French, Alison J.; Choi, Sungshin; Stewart, Helen J.

2017-01-01

The NASA Ames Institutional Scientific Collection involves the Ames Life Sciences Data Archive (ALSDA) and a biospecimen repository, which are responsible for archiving information and non-human biospecimens collected from spaceflight and matching ground control experiments. The ALSDA also manages a biospecimen sharing program, performs curation and long-term storage operations, and facilitates distribution of biospecimens for research purposes via a public website (https:lsda.jsc.nasa.gov). As part of our best practices, a tissue viability testing plan has been developed for the repository, which will assess the quality of samples subjected to long-term storage. We expect that the test results will confirm usability of the samples, enable broader science community interest, and verify operational efficiency of the archives. This work will also support NASA open science initiatives and guides development of NASA directives and policy for curation of biological collections.

The NASA Ames Polycyclic Aromatic Hydrocarbon Infrared Spectroscopic Database : The Computed Spectra

NARCIS (Netherlands)

Bauschlicher, C. W.; Boersma, C.; Ricca, A.; Mattioda, A. L.; Cami, J.; Peeters, E.; de Armas, F. Sanchez; Saborido, G. Puerta; Hudgins, D. M.; Allamandola, L. J.

The astronomical emission features, formerly known as the unidentified infrared bands, are now commonly ascribed to polycyclic aromatic hydrocarbons (PAHs). The laboratory experiments and computational modeling done at the NASA Ames Research Center to create a collection of PAH IR spectra relevant

NASA Ames Sustainability Initiatives: Aeronautics, Space Exploration, and Sustainable Futures

Science.gov (United States)

Grymes, Rosalind A.

2015-01-01

In support of the mission-specific challenges of aeronautics and space exploration, NASA Ames produces a wealth of research and technology advancements with significant relevance to larger issues of planetary sustainability. NASA research on NexGen airspace solutions and its development of autonomous and intelligent technologies will revolutionize both the nation's air transporation systems and have applicability to the low altitude flight economy and to both air and ground transporation, more generally. NASA's understanding of the Earth as a complex of integrated systems contributes to humanity's perception of the sustainability of our home planet. Research at NASA Ames on closed environment life support systems produces directly applicable lessons on energy, water, and resource management in ground-based infrastructure. Moreover, every NASA campus is a 'city'; including an urbanscape and a workplace including scientists, human relations specialists, plumbers, engineers, facility managers, construction trades, transportation managers, software developers, leaders, financial planners, technologists, electricians, students, accountants, and even lawyers. NASA is applying the lessons of our mission-related activities to our urbanscapes and infrastructure, and also anticipates a leadership role in developing future environments for living and working in space.

Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice.

Science.gov (United States)

Rojanathammanee, Lalida; Rakoczy, Sharlene; Brown-Borg, Holly M

2014-10-01

Ames dwarf mice are deficient in growth hormone (GH), prolactin, and thyroid-stimulating hormone and live significantly longer than their wild-type (WT) siblings. The lack of GH is associated with stress resistance and increased longevity. However, the mechanism underlying GH's actions on cellular stress defense have yet to be elucidated. In this study, WT or Ames dwarf mice were treated with saline or GH (WT saline, Dwarf saline, and Dwarf GH) two times daily for 7 days. The body and liver weights of Ames dwarf mice were significantly increased after 7 days of GH administration. Mitochondrial protein levels of the glutathione S-transferase (GST) isozymes, K1 and M4 (GSTK1 and GSTM4), were significantly higher in dwarf mice (Dwarf saline) when compared with WT mice (WT saline). GH administration downregulated the expression of GSTK1 proteins in dwarf mice. We further investigated GST activity from liver lysates using different substrates. Substrate-specific GST activity (bromosulfophthalein, dichloronitrobenzene, and 4-hydrox-ynonenal) was significantly reduced in GH-treated dwarf mice. In addition, GH treatment attenuated the activity of thioredoxin and glutaredoxin in liver mitochondria of Ames mice. Importantly, GH treatment suppressed Trx2 and TrxR2 mRNA expression. These data indicate that GH has a role in stress resistance by altering the functional capacity of the GST system through the regulation of specific GST family members in long-living Ames dwarf mice. It also affects the regulation of thioredoxin and glutaredoxin, factors that regulate posttranslational modification of proteins and redox balance, thereby further influencing stress resistance. © The Author 2013. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Long-lived hypopituitary Ames dwarf mice are resistant to the detrimental effects of high-fat diet on metabolic function and energy expenditure.

Science.gov (United States)

Hill, Cristal M; Fang, Yimin; Miquet, Johanna G; Sun, Liou Y; Masternak, Michal M; Bartke, Andrzej

2016-06-01

Growth hormone (GH) signaling stimulates the production of IGF-1; however, increased GH signaling may induce insulin resistance and can reduce life expectancy in both mice and humans. Interestingly, disruption of GH signaling by reducing plasma GH levels significantly improves health span and extends lifespan in mice, as observed in Ames dwarf mice. In addition, these mice have increased adiposity, yet are more insulin sensitive compared to control mice. Metabolic stressors such as high-fat diet (HFD) promote obesity and may alter longevity through the GH signaling pathway. Therefore, our objective was to investigate the effects of a HFD (metabolic stressor) on genetic mechanisms that regulate metabolism during aging. We show that Ames dwarf mice fed HFD for 12 weeks had an increase in subcutaneous and visceral adiposity as a result of diet-induced obesity, yet are more insulin sensitive and have higher levels of adiponectin compared to control mice fed HFD. Furthermore, energy expenditure was higher in Ames dwarf mice fed HFD than in control mice fed HFD. Additionally, we show that transplant of epididymal white adipose tissue (eWAT) from Ames dwarf mice fed HFD into control mice fed HFD improves their insulin sensitivity. We conclude that Ames dwarf mice are resistant to the detrimental metabolic effects of HFD and that visceral adipose tissue of Ames dwarf mice improves insulin sensitivity in control mice fed HFD. © 2016 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

Ames Laboratory site environmental report, Calendar year 1994

International Nuclear Information System (INIS)

1994-01-01

The Ames Laboratory conducts fundamental research in the physical, chemical, materials, and mathematical sciences and engineering which underlie energy generating, conversion, transmission and storage technologies, environmental improvement, and other technical areas essential to national needs. These efforts will be maintained so as to contribute to the achievement of the vision of DOE and, more specifically, to increase the general levels of knowledge and technical capabilities, to prepare engineering and physical sciences students for the future, both academia and industry, and to develop new technologies and practical applications from our basic scientific programs that will contribute to a strengthening of the US economy. The Laboratory approaches all its operations with the safety and health of all workers as a constant objective and with genuine concern for the environment. The Laboratory relies upon its strengths in materials synthesis and processing, materials reliability, chemical analysis, chemical sciences, photosynthesis, materials sciences, metallurgy, high-temperature superconductivity, and applied mathematical sciences to conduct the long term basic and intermediate range applied research needed to solve the complex problems encountered in energy production, and utilization as well as environmental restoration and waste management. Ames Laboratory will continue to maintain a very significant and highly beneficial pre-college math and science education program which currently serves both teachers and students at the middle school and high school levels. Our technology transfer program is aided by joint efforts with ISU's technology development and commercialization enterprise and will sustain concerted efforts to implement Cooperative Research and Development Agreements, industrially sponsored Work for Others projects. and scientific personnel exchanges with our various customers

Exploration of a steamship wreck off Amee shoals, Goa, India: A preliminary report

Digital Repository Service at National Institute of Oceanography (India)

Tripati, S.; Gaur, A; Sundaresh

Recent explorations off Amee shoals, Goa, have brought to light the remains of a steel-hulled steam-engine shipwreck, scattered over a large area. Though sparse and heavily salvaged, this site represents the first discovery of a steamship wreck...

Voluntary cleanup of the Ames chemical disposal site

International Nuclear Information System (INIS)

Taboas, A.L.; Freeman, R.; Peterson, J.

2003-01-01

The U.S. Department of Energy completed a voluntary removal action at the Ames chemical disposal site, a site associated with the early days of the Manhattan Project. It contained chemical and low-level radioactive wastes from development of the technology to extract uranium from uranium oxide. The process included the preparation of a Remedial Investigation, Feasibility Study, Baseline Risk Assessment, and, ultimately, issuance of a Record of Decision. Various stakeholder groups were involved, including members of the regulatory community, the general public, and the landowner, Iowa State University. The site was restored and returned to the landowner for unrestricted use.

The AMES Laboratory chemical disposal site removal action: Source removal, processing, and disposal

International Nuclear Information System (INIS)

Shirley, R.S.

1996-01-01

The Ames Laboratory has historically supported the U.S. Department of Energy (USDOE) and its predecessor agencies by providing research into the purification and manufacturing of high purity uranium, thorium, and yttrium metals. Much of this work was accomplished in the late 1950s and early 1960s prior to the legislation of strict rules and regulations covering the disposal of radioactive and chemical wastes. As a result, approximately 800 cubic meters of low-level radioactive wastes, chemical wastes, and contaminated debris were disposed in nine near surface cells located in a 0.75 hectare plot of land owned by Iowa State University in Ames, Iowa. Under a national contract with the U.S. Army Corps of Engineers (USACE), OHM Remediation Services Corp (OHM) was tasked with providing turnkey environmental services to remove, process, package, transport, and coordinate the disposal of the waste materials and contaminated environmental media

The Ames Laboratory Chemical Disposal Site removal action: Source removal, processing, and disposal

International Nuclear Information System (INIS)

Shirley, R.S.

1995-01-01

The Ames Laboratory has historically supported the US Department of Energy (USDOE) and its predecessor agencies by providing research into the purification and manufacturing of high purity uranium, thorium, and yttrium metals. Much of this work was accomplished in the late 1950s and early 1960s prior to the legislation of strict rules and regulations covering the disposal of radioactive and chemical wastes. As a result, approximately 800 cubic meters of low-level radioactive wastes, mixed wastes, and contaminated debris were disposed in nine near surface cells located in a 0.75 hectare plot of land owned by Iowa State University in Ames, Iowa. Under a national contract with the US Army Corps of Engineers (USACE), OHM Remediation Services Corp. (OHM) was tasked with providing turnkey environmental services to remove, process, package, transport, and coordinate the disposal of the waste materials and contaminated environmental media

Penentuan Titik Lokasi Pelabuhan Penyeberangan Amed Di Kabupaten Karangasem

Directory of Open Access Journals (Sweden)

I Gusti Ngurah Putra Dirgayusa

2016-07-01

Full Text Available Accumulation of social activity, economy and transportation that occur in Southern part of Bali adversely affects at transportation infrastructure carrying activity in this area. These require the government to get the solution of this problem. Through spatial planning area of Bali province 2005, governments establish Amed Bay developed as crossing harbor. These cases mean to divide the shout hem traffic line and support the development in northern part of Bali. The object of this research is in Purwakerti village, district of Abang, Karangasem regency. Research held based on technical and legality review. In advance analyze of those aspects that established some alterative potential location based on area requirement and mapping survey result. Following, each location alternative disassembly and examined their advantages and disadvantages in each aspect. Technical aspect analyze of land and territorial water technique. The approach that used in harbor location selection for this technique is weighting and assessment method in assessment matrix. The weighting value that used refers to harbor location selection in Makian bay. Meanwhile, for legality aspect, analyzed by policy review that relate to spatial area and location selection of harbor development. Based on minimum area demand analyze that 0.7 Ha for land facilities and 15.8 Ha for waters facilities. Refers to minimum area demand and layout spatial survey, four locations are selected for alternative points. After technical and legality aspect analyzed, then obtained second area chosen which located in Amed country, Purwakerti village.

Assessment of diphenylcyclopropenone for photochemically induced mutagenicity in the Ames assay

Energy Technology Data Exchange (ETDEWEB)

Wilkerson, M.G.; Connor, T.H.; Henkin, J.; Wilkin, J.K.; Matney, T.S.

1987-10-01

The photochemical conversion of diphenylcyclopropenone to diphenylacetylene has recently been reported. Diphenylcyclopropenone is used in the treatment of alopecia areata and is nonmutagenic in a limited Ames assay. We examined diphenylcyclopropenone and diphenylacetylene, as well as synthetic precursors of diphenylcyclopropenone--dibenzylketone and alpha,alpha'-dibromodibenzylketone--for mutagenicity against TA100, TA98, TA102, UTH8413, and UTH8414. All compounds were nonmutagenic except alpha,alpha'-dibromodibenzylketone, which was a potent mutagen in TA100 with and without S-9 activation. The effect of photochemical activation of diphenylcyclopropenone in the presence of bacteria demonstrated mutagenicity in UTH8413 (two times background) at 10 micrograms/plate with S-9 microsomal activation. 8-Methoxypsoralen produces a mutagenic response in TA102 at 0.1 microgram/plate with 60 seconds of exposure to 350 nm light. In vitro photochemically activated Ames assay with S-9 microsomal fraction may enhance the trapping of short-lived photochemically produced high-energy mutagenic intermediates. This technique offers exciting opportunities to trap high-energy intermediates that may play an important role in mutagenesis. This method can be applied to a variety of topically applied dermatologic agents, potentially subjected to photochemical changes in normal use.

The Ames Vertical Gun Range

Science.gov (United States)

Karcz, J. S.; Bowling, D.; Cornelison, C.; Parrish, A.; Perez, A.; Raiche, G.; Wiens, J.-P.

2016-01-01

The Ames Vertical Gun Range (AVGR) is a national facility for conducting laboratory- scale investigations of high-speed impact processes. It provides a set of light-gas, powder, and compressed gas guns capable of accelerating projectiles to speeds up to 7 km s(exp -1). The AVGR has a unique capability to vary the angle between the projectile-launch and gravity vectors between 0 and 90 deg. The target resides in a large chamber (diameter approximately 2.5 m) that can be held at vacuum or filled with an experiment-specific atmosphere. The chamber provides a number of viewing ports and feed-throughs for data, power, and fluids. Impacts are observed via high-speed digital cameras along with investigation-specific instrumentation, such as spectrometers. Use of the range is available via grant proposals through any Planetary Science Research Program element of the NASA Research Opportunities in Space and Earth Sciences (ROSES) calls. Exploratory experiments (one to two days) are additionally possible in order to develop a new proposal.

Shock Tube and Ballistic Range Facilities at NASA Ames Research Center

Science.gov (United States)

Grinstead, Jay H.; Wilder, Michael C.; Reda, Daniel C.; Cornelison, Charles J.; Cruden, Brett A.; Bogdanoff, David W.

2010-01-01

The Electric Arc Shock Tube (EAST) facility and the Hypervelocity Free Flight Aerodynamic Facility (HFFAF) at NASA Ames Research Center are described. These facilities have been in operation since the 1960s and have supported many NASA missions and technology development initiatives. The facilities have world-unique capabilities that enable experimental studies of real-gas aerothermal, gas dynamic, and kinetic phenomena of atmospheric entry.

Antimutagenic components in Glycyrrhiza against N-methyl-N-nitrosourea in the Ames assay.

Science.gov (United States)

Inami, Keiko; Mine, Yusuke; Kojo, Yukiko; Tanaka, Satomi; Ishikawa, Satoko; Mochizuki, Masataka

2017-03-01

Antimutagenesis against N-nitroso compounds contribute to prevention of human cancer. We have found that Glycyrrhiza aspera ethanolic extract exhibits antimutagenic activity against N-methyl-N-nitrosourea (MNU) using the Ames assay with Salmonella typhimurium TA1535. In the present study, eight purified components from Glycyrrhiza, namely glabridin, glycyrrhetinic acid, glycyrrhizin, licochalcone A, licoricesaponin H2, licoricesaponin G2, liquiritigenin and liquiritin were evaluated for their antimutagenicity against MNU in the Ames assay with S. typhimurium TA1535. Glycyrrhetinic acid, glycyrrhizin, licoricesaponin G2, licoricesaponin H2 and liquiritin did not show the antimutagenicity against MNU in S. typhimurium TA1535. Glabridin, licochalcone A and liquiritigenin reduced revertant colonies derived from MNU in S. typhimurium TA1535 without showing cytotoxic effects, indicating that these compounds possess antimutagenic activity against MNU. The inhibitory activity of glabridin and licochalcone A was more effective than that of liquiritigenin. Thus, Glycyrrhiza contains antimutagenic components against DNA alkylating, direct-acting carcinogens.

Estimation of γ irradiation induced genetic damage by Ames test

International Nuclear Information System (INIS)

Hosoda, Eiko

1999-01-01

Mutation by 60 Co γ irradiation was studied in five different histidine-requiring auxotrophs of Salmonella typhimurium. The strains TA98 (sensitive to frameshift) and TA100 (sensitive to base-pair substitution) were irradiated (10-84 Gy and 45-317 Gy, respectively) and revertants were counted. TA98 exhibited radiation-induced revertants, 2.8 fold of spontaneous revertants, although no significant increase was detected in TA100. Then, three other frameshift-sensitive strains TA1537, TA1538 and TA94 were irradiated in a dose of 61-167 Gy. Only in TA94, revertants increased 3.5 fold. Since spontaneous revertants are known to be independent of cell density, a decrease of bacterial number by γ irradiation was confirmed not to affect the induced revertants by dilution test. Thus the standard Ames Salmonella assay identified γ irradiation was confirmed not to affect the induced revertants by dilution test. Thus the standard Ames Salmonella assay identified γ irradiation as a mutagenetic agent. The mutagenicity of dinitropyrene, a mutagen widely existing in food, and dismutagenicity of boiling water insoluble fraction of Hizikia fusiforme, edible marine alga, were tested on γ induced revertant formation in TA98 and TA94. Dinitropyrene synergistically increased γ induced revertants and Hizikia insoluble fraction reduced the synergistic effect of dinitropyrene dependently on the concentration. (author)

The Use of the Ames Test as a Tool for Addressing Problem-Based Learning in the Microbiology Lab

Directory of Open Access Journals (Sweden)

Eliana Rodríguez

2012-08-01

Full Text Available Our environment is full of potential carcinogens such as UV light, industrial pollutants, pesticides, and food additives, among others. It is estimated that 90% of all carcinogens are also mutagens. The Ames test is one of the most common tests for mutagens. In this problem-based learning activity, undergraduate biology students used the Ames test to screen a substance they provided, to see if it could be considered a mutagen. The idea of surveying substances used in everyday life appealed to our students, and helped engage them in this activity.

Investigating the intra-nuclear cascade process using the reaction 136Xe on deuterium at 500 AMeV

Directory of Open Access Journals (Sweden)

Rejmund F.

2010-10-01

Full Text Available More than 600 residual nuclei, formed in the spallation of 136Xe projectiles impinging on deuterium at 500 AMeV of incident energy, have been unambiguously identified and their production cross sections have been determined with high accuracy. By comparing these data to others previously measured for the reactions 136Xe  +  p at 1 AGeV and 136Xe  +  p at 500 AMeV we investigated the role that neutrons play in peripheral collisions and to understand the energy dissipation in frontal collisions in spallation reactions.

Identification of a polyketide synthase required for alternariol (AOH and alternariol-9-methyl ether (AME formation in Alternaria alternata.

Directory of Open Access Journals (Sweden)

Debjani Saha

Full Text Available Alternaria alternata produces more than 60 secondary metabolites, among which alternariol (AOH and alternariol-9-methyl ether (AME are important mycotoxins. Whereas the toxicology of these two polyketide-based compounds has been studied, nothing is known about the genetics of their biosynthesis. One of the postulated core enzymes in the biosynthesis of AOH and AME is polyketide synthase (PKS. In a draft genome sequence of A. alternata we identified 10 putative PKS-encoding genes. The timing of the expression of two PKS genes, pksJ and pksH, correlated with the production of AOH and AME. The PksJ and PksH proteins are predicted to be 2222 and 2821 amino acids in length, respectively. They are both iterative type I reducing polyketide synthases. PksJ harbors a peroxisomal targeting sequence at the C-terminus, suggesting that the biosynthesis occurs at least partly in these organelles. In the vicinity of pksJ we found a transcriptional regulator, altR, involved in pksJ induction and a putative methyl transferase, possibly responsible for AME formation. Downregulation of pksJ and altR caused a large decrease of alternariol formation, suggesting that PksJ is the polyketide synthase required for the postulated Claisen condensations during the biosynthesis. No other enzymes appeared to be required. PksH downregulation affected pksJ expression and thus caused an indirect effect on AOH production.

Assaying the Mutagenic Potential of ELF Radiation through Reverse Mutagenesis via the Ames Test

National Research Council Canada - National Science Library

Moga, Paul

1996-01-01

...) on certain strains of Salmonella typhimurium. The strain of S-typhimurium used in the Ames test has a mutation on one gene of the histidine operon which prevents it from growing and replicating without the presence of histidine in the media...

The AMES network in the 6th Framework Programme

International Nuclear Information System (INIS)

Sevini, F.; Debarberis, L.; Taylor, N.; Gerard, R.; English, C.; Brumovsky, M.

2003-01-01

The AMES (Ageing Materials European Strategy) European network started its activity in 1993 with the aim of studying ageing mechanisms and remedial procedures for structural materials used for nuclear reactor components. Operated by JRC-IE, it has been supporting the co-ordination of the project cluster throughout the 4th and 5th EURATOM Framework Programs, carrying out projects on with plant life management implications. Among them we can list the development of non-destructive techniques applied to thermal ageing and neutron embrittlement monitoring (AMES-NDT and GRETE), improved surveillance for VVER 440 reactors (COBRA), dosimetry (AMESDOSIMETRY, MADAM and REDOS), chemical composition effects on neutron embrittlement (PISA) and advanced fracture mechanics for integrity assessment (FRAME). Main frame of the network in the 5th Framework Programme is the ATHENA project, which is aimed at summarizing the obtained achievements and edit guidelines on important issues like the Master Curve, Effect of chemical composition on embrittlement rate in RPV steels, Re-embrittlement models validation after VVER-440 annealing and open issues in embrittlement of VVER type reactors. In the 6th EURATOM Framework Programme started in 2003 the network will be part of a broader initiative on PLIM including in a more integrated way NESC, ENIQ, NET and AMALIA networks. This paper shows an overview of the concluded projects, achievements of the running ones and open issues tackled in the 6th EURATOM FWP and a summary of the plans for a new broader network on NPP Plant Life management (SAFELIFE). (author)

Original Research: Metabolic alterations from early life thyroxine replacement therapy in male Ames dwarf mice are transient.

Science.gov (United States)

Darcy, Justin; Fang, Yimin; Hill, Cristal M; McFadden, Sam; Sun, Liou Y; Bartke, Andrzej

2016-10-01

Ames dwarf mice are exceptionally long-lived due to a Prop1 loss of function mutation resulting in deficiency of growth hormone, thyroid-stimulating hormone and prolactin. Deficiency in thyroid-stimulating hormone and growth hormone leads to greatly reduced levels of circulating thyroid hormones and insulin-like growth factor 1, as well as a reduction in insulin secretion. Early life growth hormone replacement therapy in Ames dwarf mice significantly shortens their longevity, while early life thyroxine (T4) replacement therapy does not. Possible mechanisms by which early life growth hormone replacement therapy shortens longevity include deleterious effects on glucose homeostasis and energy metabolism, which are long lasting. A mechanism explaining why early life T4 replacement therapy does not shorten longevity remains elusive. Here, we look for a possible explanation as to why early life T4 replacement therapy does not impact longevity of Ames dwarf mice. We found that early life T4 replacement therapy increased body weight and advanced the age of sexual maturation. We also find that early life T4 replacement therapy does not impact glucose tolerance or insulin sensitivity, and any deleterious effects on oxygen consumption, respiratory quotient and heat production are transient. Lastly, we find that early life T4 replacement therapy has long-lasting effects on bone mineral density and bone mineral content. We suggest that the transient effects on energy metabolism and lack of effects on glucose homeostasis are the reasons why there is no shortening of longevity after early life T4 replacement therapy in Ames dwarf mice. © 2016 by the Society for Experimental Biology and Medicine.

Mutagenic and antimutagenic activities of bioflavonoids and structural analogues in the Ames/Salmonella test

NARCIS (Netherlands)

Mohn GR; Van der Stel JJ; Stavenuiter JFC; Hamzink MRJ; Kreijl CF; LEO; LBO

1996-01-01

The mutagenic and antimutagenic properties of bioflavonoids were determined in the bacterial mutagenicity test of Ames, using Salmonella typhimurium strains TA98 and TA100. The decreasing order of mutagenic activity found in both strains was quercetin>myricetin-kaempferol>morin hydrate. The

Thyroxine modifies the effects of growth hormone in Ames dwarf mice.

Science.gov (United States)

Do, Andrew; Menon, Vinal; Zhi, Xu; Gesing, Adam; Wiesenborn, Denise S; Spong, Adam; Sun, Liou; Bartke, Andrzej; Masternak, Michal M

2015-04-01

Ames dwarf (df/df) mice lack growth hormone (GH), thyroid stimulating hormone and prolactin. Treatment of juvenile df/df mice with GH alone stimulates somatic growth, reduces insulin sensitivity and shortens lifespan. Early-life treatment with thyroxine (T4) alone produces modest growth stimulation but does not affect longevity. In this study, we examined the effects of treatment of juvenile Ames dwarf mice with a combination of GH + T4 and compared them to the effects of GH alone. Treatment of female and male dwarfs with GH + T4 between the ages of 2 and 8 weeks rescued somatic growth yet did not reduce lifespan to match normal controls, thus contrasting with the previously reported effects of GH alone. While the male dwarf GH + T4 treatment group had no significant effect on lifespan, the female dwarfs undergoing treatment showed a decrease in maximal longevity. Expression of genes related to GH and insulin signaling in the skeletal muscle and white adipose tissue (WAT) of female dwarfs was differentially affected by treatment with GH + T4 vs. GH alone. Differences in the effects of GH + T4 vs. GH alone on insulin target tissues may contribute to the differential effects of these treatments on longevity.

Mutagenicity of anthraquinone and hydroxylated anthraquinones in the Ames/Salmonella microsome system.

Science.gov (United States)

Liberman, D F; Fink, R C; Schaefer, F L; Mulcahy, R J; Stark, A A

1982-01-01

The mutagenicity of anthracene, anthraquinone, and four structurally similar compounds of each was evaluated in the Ames/Salmonella microsome assay. Anthraquinone was shown to be mutagenic for strains TA1537, TA1538, and TA98 in the absence of rat liver homogenate. The four anthraquinone derivatives tested were mutagenic for TA1537 exclusively. None of the anthracenes exhibited mutagenic activity. PMID:7103489

Mutagenicity of anthraquinone and hydroxylated anthraquinones in the Ames/Salmonella microsome system.

OpenAIRE

Liberman, D F; Fink, R C; Schaefer, F L; Mulcahy, R J; Stark, A A

1982-01-01

The mutagenicity of anthracene, anthraquinone, and four structurally similar compounds of each was evaluated in the Ames/Salmonella microsome assay. Anthraquinone was shown to be mutagenic for strains TA1537, TA1538, and TA98 in the absence of rat liver homogenate. The four anthraquinone derivatives tested were mutagenic for TA1537 exclusively. None of the anthracenes exhibited mutagenic activity.

Ames life science telescience testbed evaluation

Science.gov (United States)

Haines, Richard F.; Johnson, Vicki; Vogelsong, Kristofer H.; Froloff, Walt

1989-01-01

Eight surrogate spaceflight mission specialists participated in a real-time evaluation of remote coaching using the Ames Life Science Telescience Testbed facility. This facility consisted of three remotely located nodes: (1) a prototype Space Station glovebox; (2) a ground control station; and (3) a principal investigator's (PI) work area. The major objective of this project was to evaluate the effectiveness of telescience techniques and hardware to support three realistic remote coaching science procedures: plant seed germinator charging, plant sample acquisition and preservation, and remote plant observation with ground coaching. Each scenario was performed by a subject acting as flight mission specialist, interacting with a payload operations manager and a principal investigator expert. All three groups were physically isolated from each other yet linked by duplex audio and color video communication channels and networked computer workstations. Workload ratings were made by the flight and ground crewpersons immediately after completing their assigned tasks. Time to complete each scientific procedural step was recorded automatically. Two expert observers also made performance ratings and various error assessments. The results are presented and discussed.

Feature combination networks for the interpretation of statistical machine learning models: application to Ames mutagenicity.

Science.gov (United States)

Webb, Samuel J; Hanser, Thierry; Howlin, Brendan; Krause, Paul; Vessey, Jonathan D

2014-03-25

A new algorithm has been developed to enable the interpretation of black box models. The developed algorithm is agnostic to learning algorithm and open to all structural based descriptors such as fragments, keys and hashed fingerprints. The algorithm has provided meaningful interpretation of Ames mutagenicity predictions from both random forest and support vector machine models built on a variety of structural fingerprints.A fragmentation algorithm is utilised to investigate the model's behaviour on specific substructures present in the query. An output is formulated summarising causes of activation and deactivation. The algorithm is able to identify multiple causes of activation or deactivation in addition to identifying localised deactivations where the prediction for the query is active overall. No loss in performance is seen as there is no change in the prediction; the interpretation is produced directly on the model's behaviour for the specific query. Models have been built using multiple learning algorithms including support vector machine and random forest. The models were built on public Ames mutagenicity data and a variety of fingerprint descriptors were used. These models produced a good performance in both internal and external validation with accuracies around 82%. The models were used to evaluate the interpretation algorithm. Interpretation was revealed that links closely with understood mechanisms for Ames mutagenicity. This methodology allows for a greater utilisation of the predictions made by black box models and can expedite further study based on the output for a (quantitative) structure activity model. Additionally the algorithm could be utilised for chemical dataset investigation and knowledge extraction/human SAR development.

Ames collaborative study of cosmic-ray neutrons. II. Low- and mid-latitude flights

International Nuclear Information System (INIS)

Stephens, L.D.; McCaslin, J.B.; Smith, A.R.; Thomas, R.H.; Hewitt, J.E.; Hughes, L.

1978-01-01

The continuing progress of the Ames Collaborative Study of Cosmic Ray Neutrons is described. Data obtained aboard flights from Hawaii at altitudes of 41,000 and 45,000 feet, and in the range of geomagnetic latitude 17 0 N less than or equal to lambda less than or equal to 21 0 N are reported. Preliminary estimates of neutron spectra were made

Mutagenicity of Flavonoids Assayed by Bacterial Reverse Mutation (Ames Test

Directory of Open Access Journals (Sweden)

Eliana Aparecida Varanda

2012-05-01

Full Text Available The mutagenicity of ten flavonoids was assayed by the Ames test, in Salmonella typhimurium strains TA98, TA100 and TA102, with the aim of establishing hydroxylation pattern-mutagenicity relationship profiles. The compounds assessed were: quercetin, kaempferol, luteolin, fisetin, chrysin, galangin, flavone, 3-hydroxyflavone, 5-hydroxyflavone and 7-hydroxyflavone. In the Ames assay, quercetin acted directly and its mutagenicity increased with metabolic activation. In the presence of S9 mix, kaempferol and galangin were mutagenic in the TA98 strain and kaempferol showed signs of mutagenicity in the other strains. The absence of hydroxyl groups, as in flavone, only signs of mutagenicity were shown in strain TA102, after metabolization and, among monohydroxylated flavones (3-hydroxyflavone, 5-hydroxyflavone and 7-hydroxyflavone, the presence of hydroxyl groups only resulted in minor changes. Luteolin and fisetin also showed signs of mutagenicity in strain TA102. Finally, chrysin, which has only two hydroxy groups, at the 5-OH and 7-OH positions, also did not induce mutagenic activity in any of the bacterial strains used, under either activation condition. All the flavonoids were tested at concentrations varying from 2.6 to 30.7 nmol/plate for galangin and 12.1 to 225.0 nmol/plate for other flavonoids. In light of the above, it is necessary to clarify the conditions and the mechanisms that mediate the biological effects of flavonoids before treating them as therapeutical agents, since some compounds can be biotransformed into more genotoxic products; as is the case for galangin, kaempferol and quercetin.

Are effects of common ragwort in the Ames test caused by pyrrolizidine alkaloids?

Science.gov (United States)

Bovee, Toine F H; Helsdingen, Richard J R; Hoogenboom, Ron L A P; de Nijs, Monique W C M; Liu, Xiaojie; Vrieling, Klaas; Klinkhamer, Peter G L; Peijnenburg, Ad A C M; Mulder, Patrick P J

2015-08-01

It has previously been demonstrated by others that acetone extracts of Senecio jacobaea (syn. Jacobaea vulgaris, common or tansy ragwort) test positive in the Salmonella/microsome mutagenicity test (Ames test). Pyrrolizidine alkaloids (PAs) are thought to be responsible for these mutagenic effects. However, it was also observed that the major PA present in common ragwort, jacobine, produced a negative response (with and without the addition of rat liver S9) in Salmonella test strains TA98, TA100, TA1535 and TA1537. To investigate which compounds in the plant extracts were responsible for the positive outcome, the present study investigated the contents and mutagenic effects of methanol and acetone extracts prepared from dried ground S. jacobaea and Senecio inaequidens (narrow-leafed ragwort). Subsequently, a fractionation approach was set up in combination with LC-MS/MS analysis of the fractions. It was shown that the positive Ames test outcomes of S. jacobaea extracts are unlikely to be caused by PAs, but rather by the flavonoid quercetin. This study also demonstrates the importance of identifying compounds responsible for positive test results in bioassays. Copyright © 2015 Elsevier B.V. All rights reserved.

State of the Art High-Throughput Approaches to Genotoxicity: Flow Micronucleus, Ames II, GreenScreen and Comet

Science.gov (United States)

State of the Art High-Throughput Approaches to Genotoxicity: Flow Micronucleus, Ames II, GreenScreen and Comet (Presented by Dr. Marilyn J. Aardema, Chief Scientific Advisor, Toxicology, Dr. Leon Stankowski, et. al. (6/28/2012)

Analysis of plant extracts antimutagenicity using the Ames test and the cytogenetic analysis of peripheral blood lymphocytes

Czech Academy of Sciences Publication Activity Database

Buňková, R.; Marová, I.; Pokorná, Z.; Lojek, Antonín

2005-01-01

Roč. 11, č. 2 (2005), s. 107-112 ISSN 1082-0132 Institutional research plan: CEZ:AV0Z50040507 Keywords : plant extracts * antioxidative activity * Ames test Subject RIV: BO - Biophysics Impact factor: 0.724, year: 2005

Out-of-plane emission of nuclear matter in Au+Au collisions between 100 and 800 AMeV

International Nuclear Information System (INIS)

Bastid, N.; Buta, A.; Crochet, P.

1996-01-01

We present new experimental results concerning the azimuthal distributions of light and intermediate mass fragments at midrapidity for Au (100 - 800 AMeV) +Au collisions measured with the phase I setup of the FOPI detector at GSI in Darmstadt. The azimuthal distributions are investigated as a function of the collision centrality, the incident energy, the fragment charge and transverse momentum. The maximum of the azimuthal anisotropy is obtained for collisions associated with impact parameters around 7 fm. Intermediate mass fragments present a stronger out-of-plane emission signal that light fragments. We show in particular that the azimuthal anisotropy as a function of the scaled fragment transverse momentum follows an universal curve for incident energies ranging from 250 to 800 AMeV. A signature for a transition from in-plane to out-of-plane emission is evidenced at the lowest beam energies. (author)

The Typical Different Features of Grammar of the British English (BrE and American English (AmE

Directory of Open Access Journals (Sweden)

I Wayan Dirgeyasa

2016-08-01

Full Text Available There are a number of varieties of English all over the world such as American, British, Australian, Indian, Singaporean, Philippine English, etc. However, there are only two varieties of English which are most widely and dominantly taught, learned, and used both spoken and printed around the world namely British English (BrE and American English (AmE. In real sense, the two are often confusing for the non-native learners because they have some differences and uniqueness in some aspects such as spelling, pronunciation, vocabulary, and grammar. Therefore, it is really important for students, teachers and speakers as well to be aware of the major differences between the two. This paper is trying to review some striking unique and different features of grammar of British English (BrE and American English (AmE.

Out-of-plane emission of nuclear matter in Au+Au collisions between 100 and 800 AMeV

Energy Technology Data Exchange (ETDEWEB)

Bastid, N.; Buta, A.; Crochet, P. [and others; FOPI Collaboration

1996-12-31

We present new experimental results concerning the azimuthal distributions of light and intermediate mass fragments at midrapidity for Au (100 - 800 AMeV) +Au collisions measured with the phase I setup of the FOPI detector at GSI in Darmstadt. The azimuthal distributions are investigated as a function of the collision centrality, the incident energy, the fragment charge and transverse momentum. The maximum of the azimuthal anisotropy is obtained for collisions associated with impact parameters around 7 fm. Intermediate mass fragments present a stronger out-of-plane emission signal that light fragments. We show in particular that the azimuthal anisotropy as a function of the scaled fragment transverse momentum follows an universal curve for incident energies ranging from 250 to 800 AMeV. A signature for a transition from in-plane to out-of-plane emission is evidenced at the lowest beam energies. (author).

Prevention of neuromusculoskeletal frailty in slow-aging ames dwarf mice: longitudinal investigation of interaction of longevity genes and caloric restriction.

Directory of Open Access Journals (Sweden)

Oge Arum

Full Text Available Ames dwarf (Prop1 (df/df mice are remarkably long-lived and exhibit many characteristics of delayed aging and extended healthspan. Caloric restriction (CR has similar effects on healthspan and lifespan, and causes an extension of longevity in Ames dwarf mice. Our study objective was to determine whether Ames dwarfism or CR influence neuromusculoskeletal function in middle-aged (82 ± 12 weeks old or old (128 ± 14 w.o. mice. At the examined ages, strength was improved by dwarfism, CR, and dwarfism plus CR in male mice; balance/ motor coordination was improved by CR in old animals and in middle-aged females; and agility/ motor coordination was improved by a combination of dwarfism and CR in both genders of middle-aged mice and in old females. Therefore, extension of longevity by congenital hypopituitarism is associated with improved maintenance of the examined measures of strength, agility, and motor coordination, key elements of frailty during human aging, into advanced age. This study serves as a particularly important example of knowledge related to addressing aging-associated diseases and disorders that results from studies in long-lived mammals.

Prevention of neuromusculoskeletal frailty in slow-aging ames dwarf mice: longitudinal investigation of interaction of longevity genes and caloric restriction.

Science.gov (United States)

Arum, Oge; Rasche, Zachary Andrew; Rickman, Dustin John; Bartke, Andrzej

2013-01-01

Ames dwarf (Prop1 (df/df) ) mice are remarkably long-lived and exhibit many characteristics of delayed aging and extended healthspan. Caloric restriction (CR) has similar effects on healthspan and lifespan, and causes an extension of longevity in Ames dwarf mice. Our study objective was to determine whether Ames dwarfism or CR influence neuromusculoskeletal function in middle-aged (82 ± 12 weeks old) or old (128 ± 14 w.o.) mice. At the examined ages, strength was improved by dwarfism, CR, and dwarfism plus CR in male mice; balance/ motor coordination was improved by CR in old animals and in middle-aged females; and agility/ motor coordination was improved by a combination of dwarfism and CR in both genders of middle-aged mice and in old females. Therefore, extension of longevity by congenital hypopituitarism is associated with improved maintenance of the examined measures of strength, agility, and motor coordination, key elements of frailty during human aging, into advanced age. This study serves as a particularly important example of knowledge related to addressing aging-associated diseases and disorders that results from studies in long-lived mammals.

THE NASA AMES PAH IR SPECTROSCOPIC DATABASE VERSION 2.00: UPDATED CONTENT, WEB SITE, AND ON(OFF)LINE TOOLS

Energy Technology Data Exchange (ETDEWEB)

Boersma, C.; Mattioda, A. L.; Allamandola, L. J. [NASA Ames Research Center, MS 245-6, Moffett Field, CA 94035 (United States); Bauschlicher, C. W. Jr.; Ricca, A. [NASA Ames Research Center, MS 230-3, Moffett Field, CA 94035 (United States); Cami, J.; Peeters, E.; De Armas, F. Sánchez; Saborido, G. Puerta [SETI Institute, 189 Bernardo Avenue 100, Mountain View, CA 94043 (United States); Hudgins, D. M., E-mail: Christiaan.Boersma@nasa.gov [NASA Headquarters, MS 3Y28, 300 E St. SW, Washington, DC 20546 (United States)

2014-03-01

A significantly updated version of the NASA Ames PAH IR Spectroscopic Database, the first major revision since its release in 2010, is presented. The current version, version 2.00, contains 700 computational and 75 experimental spectra compared, respectively, with 583 and 60 in the initial release. The spectra span the 2.5-4000 μm (4000-2.5 cm{sup -1}) range. New tools are available on the site that allow one to analyze spectra in the database and compare them with imported astronomical spectra as well as a suite of IDL object classes (a collection of programs utilizing IDL's object-oriented programming capabilities) that permit offline analysis called the AmesPAHdbIDLSuite. Most noteworthy among the additions are the extension of the computational spectroscopic database to include a number of significantly larger polycyclic aromatic hydrocarbons (PAHs), the ability to visualize the molecular atomic motions corresponding to each vibrational mode, and a new tool that allows one to perform a non-negative least-squares fit of an imported astronomical spectrum with PAH spectra in the computational database. Finally, a methodology is described in the Appendix, and implemented using the AmesPAHdbIDLSuite, that allows the user to enforce charge balance during the fitting procedure.

Ames S-32 O-16 O-18 Line List for High-Resolution Experimental IR Analysis

Science.gov (United States)

Huang, Xinchuan; Schwenke, David W.; Lee, Timothy J.

2016-01-01

By comparing to the most recent experimental data and spectra of the SO2 628 ?1/?3 bands (see Ulenikov et al., JQSRT 168 (2016) 29-39), this study illustrates the reliability and accuracy of the Ames-296K SO2 line list, which is accurate enough to facilitate such high-resolution spectroscopic analysis. The SO2 628 IR line list is computed on a recently improved potential energy surface (PES) refinement, denoted Ames-Pre2, and the published purely ab initio CCSD(T)/aug-cc-pVQZ dipole moment surface. Progress has been made in both energy level convergence and rovibrational quantum number assignments agreeing with laboratory analysis models. The accuracy of the computed 628 energy levels and line list is similar to what has been achieved and reported for SO2 626 and 646, i.e. 0.01-0.03 cm(exp -1) for bands up to 5500 cm(exp -1). During the comparison, we found some discrepancies in addition to overall good agreements. The three-IR-list based feature-by-feature analysis in a 0.25 cm(exp -1) spectral window clearly demonstrates the power of the current Ames line lists with new assignments, correction of some errors, and intensity contributions from varied sources including other isotopologues. We are inclined to attribute part of detected discrepancies to an incomplete experimental analysis and missing intensity in the model. With complete line position, intensity, and rovibrational quantum numbers determined at 296 K, spectroscopic analysis is significantly facilitated especially for a spectral range exhibiting such an unusually high density of lines. The computed 628 rovibrational levels and line list are accurate enough to provide alternatives for the missing bands or suspicious assignments, as well as helpful to identify these isotopologues in various celestial environments. The next step will be to revisit the SO2 828 and 646 spectral analyses.

Sixth Annual NASA Ames Space Science and Astrobiology Jamboree

Science.gov (United States)

Hollingsworth, Jeffery; Howell, Steve; Fonda, Mark; Dateo, Chris; Martinez, Christine M.

2018-01-01

Welcome to the Sixth Annual NASA Ames Research Center, Space Science and Astrobiology Jamboree at NASA Ames Research Center (ARC). The Space Science and Astrobiology Division consists of over 60 Civil Servants, with more than 120 Cooperative Agreement Research Scientists, Post-Doctoral Fellows, Science Support Contractors, Visiting Scientists, and many other Research Associates. Within the Division there is engagement in scientific investigations over a breadth of disciplines including Astrobiology, Astrophysics, Exobiology, Exoplanets, Planetary Systems Science, and many more. The Division's personnel support NASA spacecraft missions (current and planned), including SOFIA, K2, MSL, New Horizons, JWST, WFIRST, and others. Our top-notch science research staff is spread amongst three branches in five buildings at ARC. Naturally, it can thus be difficult to remain abreast of what fellow scientific researchers pursue actively, and then what may present and/or offer regarding inter-Branch, intra-Division future collaborative efforts. In organizing this annual jamboree, the goals are to offer a wholesome, one-venue opportunity to sense the active scientific research and spacecraft mission involvement within the Division; and to facilitate communication and collaboration amongst our research scientists. Annually, the Division honors one senior research scientist with a Pollack Lecture, and one early career research scientist with an Outstanding Early Career Space Scientist Lecture. For the Pollack Lecture, the honor is bestowed upon a senior researcher who has made significant contributions within any area of research aligned with space science and/or astrobiology. This year we are pleased to honor Linda Jahnke. With the Early Career Lecture, the honor is bestowed upon an early-career researcher who has substantially demonstrated great promise for significant contributions within space science, astrobiology, and/or, in support of spacecraft missions addressing such

Comparison of Amerlex, NML, and Ames total thyroxine and triiodothyronine radioimmunoassay kits

Energy Technology Data Exchange (ETDEWEB)

Wilke, T J; Turnbull, P A [Commonwealth Pathology Lab., Toowoomba (Australia). Dept. of Endocrinology

1982-03-01

An evaluation of the Amerlex system for determination of total thyroxine (T4) and total triiodothyronine (T3) is described. The within- and between-batch precisions were acceptable, and analyses of quality control material and linearity studies demonstrated good accuracy at the clinical decision levels. The correlations obtained with NML and Ames T4 and T3 kit methods were highly significant. The Amerlex T4 and T3 methods are rapid, technically simple, and, coupled with excellent precision and accuracy, present significant advantages.

Comparison of Amerlex, NML, and Ames total thyroxine and triiodothyronine radioimmunoassay kits

International Nuclear Information System (INIS)

Wilke, T.J.; Turnbull, P.A.

1982-01-01

An evaluation of the Amerlex system for determination of total thyroxine (T4) and total triiodothyronine (T3) is described. The within- and between-batch precisions were acceptable, and analyses of quality control material and linearity studies demonstrated good accuracy at the clinical decision levels. The correlations obtained with NML and Ames T4 and T3 kit methods were highly significant. The Amerlex T4 and T3 methods are rapid, technically simple, and, coupled with excellent precision and accuracy, present significant advantages. (author)

Scientific visualization in computational aerodynamics at NASA Ames Research Center

Science.gov (United States)

Bancroft, Gordon V.; Plessel, Todd; Merritt, Fergus; Walatka, Pamela P.; Watson, Val

1989-01-01

The visualization methods used in computational fluid dynamics research at the NASA-Ames Numerical Aerodynamic Simulation facility are examined, including postprocessing, tracking, and steering methods. The visualization requirements of the facility's three-dimensional graphical workstation are outlined and the types hardware and software used to meet these requirements are discussed. The main features of the facility's current and next-generation workstations are listed. Emphasis is given to postprocessing techniques, such as dynamic interactive viewing on the workstation and recording and playback on videodisk, tape, and 16-mm film. Postprocessing software packages are described, including a three-dimensional plotter, a surface modeler, a graphical animation system, a flow analysis software toolkit, and a real-time interactive particle-tracer.

Post-examination interpretation of objective test data: monitoring and improving the quality of high-stakes examinations--a commentary on two AMEE Guides.

Science.gov (United States)

Tavakol, Mohsen; Dennick, Reg

2012-01-01

As great emphasis is rightly placed upon the importance of assessment to judge the quality of our future healthcare professionals, it is appropriate not only to choose the most appropriate assessment method, but to continually monitor the quality of the tests themselves, in a hope that we may continually improve the process. This article stresses the importance of quality control mechanisms in the exam cycle and briefly outlines some of the key psychometric concepts including reliability measures, factor analysis, generalisability theory and item response theory. The importance of such analyses for the standard setting procedures is emphasised. This article also accompanies two new AMEE Guides in Medical Education (Tavakol M, Dennick R. Post-examination Analysis of Objective Tests: AMEE Guide No. 54 and Tavakol M, Dennick R. 2012. Post examination analysis of objective test data: Monitoring and improving the quality of high stakes examinations: AMEE Guide No. 66) which provide the reader with practical examples of analysis and interpretation, in order to help develop valid and reliable tests.

Urine recovery experiments with quercetin and other mutagens using the Ames test

Energy Technology Data Exchange (ETDEWEB)

Busch, D.B.; Hatcher, J.F.; Bryan, G.T.

1986-01-01

Recovery from urine of the mutagenic activity of 2-anthramine, cyclophosphamide, 7,12-dimethylbenz(a)anthracene, 6-chloro-9-((3-(2-chloroethylamino)-propyl)amino)-2-methoxyacridine dihydrochloride (ICR-191), mitomycin-C, nitrofurantoin, and quercetin was studied with several of the Ames tester strains using acetone-extracted XAD-2 columns with yields ranging from 27% to 79%. Dose responses of the pure chemicals were also studied, and results showed TA 97 to be far more susceptible to quercetin mutagenesis than TA 1537. Reducing pour plate agar volume enhanced mutagenesis.

ASCORBIC ACID REDUCTION OF ACTIVE CHLORINE PRIOR TO DETERMINING AMES MUTAGENICITY OF CHLORINATED NATURAL ORGANIC MATTER (NOM)

Science.gov (United States)

Many potable water disinfection byproducts (DBPs) that result from the reaction of natural organic matter (NOM) with oxidizing chlorine are known or suspected to be carcinogenic and mutagenic. The Ames assay is routinely used to assess an overall level of mutagenicity for all com...

Prophage induction, mutagenesis, and cell survival of Ames' mutagen tester strains after 8-methoxypsoralen plus ultraviolet light-A

Energy Technology Data Exchange (ETDEWEB)

Wheeler, L.A.; DeMeo, M. (California Univ., Los Angeles (USA)); Lowe, N. (Combined UCLA-WADSWORTH Dermatology Program, Los Angeles, CA (USA))

1983-10-01

8-methoxypsoralen (8-MOP) is not detected as a mutagen in the standard Ames test either in the presence or absence of S9-mix and/or ultraviolet light-A (320-400 nm). The Ames strains have been shown to harbor bacteriophages that are inducible by carcinogens and mutagens. Psoralen plus UVA (PUVA) was found to be a potent prophage inducing treatment. Induction was observed in TA1535, TA1538, TA98, TA100, TA1978 and TA1975 with 8-MOP and UVA. PUVA is a potent bactericidal treatment at concentrations of 8-MOP above 0.5 ..mu..g/ml and 2.5 kJ/m/sup 2/ in tester strains TA1535, TA1538, TA98 and TA100. PUVA is known to be bactericidal, but the cytotoxicity observed in the present study was unique in that the frameshift tester strains (TA1538 and TA98) were more sensitive to the lethal effects of PUVA than the base pair tester strains (TA1535 and TA100). The differential cytotoxicity in such closely related strains led to the examination of some of the strains from which the Ames strains were derived. It is postulated that TA1535 retains a DNA repair function that is lost by TA1538 during the selection for uvrB deficient strains.

Application of the Ames mutagenicity test to food processed by physical preservation methods

International Nuclear Information System (INIS)

Kooij, J.G. van; Leveling, H.B.; Schubert, J.

1978-01-01

An irradiated (380 krad) mixture of four fresh vegetables - leek, celery, carrot, and cauliflower - was examined for mutagenicity by the Ames mutagenicity test using four different histidine-deficient strains of Salmonellae. Water extracts were prepared from the irradiated and unirradiated vegetables - a freeze dried extract (FDE) and a boiled extract (BE). Several problems were overcome in the mutagenicity testing of a complex substance such as food which contains free histidine, different species of bacteria, and a mixture of low and high molecular weight chemicals. In addition, we eliminated an omission in the usual protocols of the Ames test by testing the positive mutagen controls in the presence and absence of the test samples, thus reducing the possible incidence of false negatives and false positives. The induction and expression of mutagenesis by sodium azide (SA) and ethidium bromide (EB) in TA 100 and TA 98 mutant strains, respectively, decreased with increasing amounts of FDE, while increasing levels of BE suppressed the number of revertants in TA 98 in the presence of EB, but exerted little influence on the mutagenicity of SA in TA 100. No difference was observed in the antimutagenic action between the irradiated and unirradiated vegetable extracts. Both the FDE and BE preparations suppressed the action of a frameshift mutagen, but with a base-pair mutagen only the FDE or uncooked vegetable extracts produced suppression. (author)

High-speed research program systems analysis activities at Ames Research Center

Science.gov (United States)

Kidwell, George H.

1992-01-01

The Ames Systems Analysis Branch has been working to support the High Speed Research Program (HSRP) for nearly one year. Both the status of methodology development activities and the results of studies are presented whether completed or underway. The discussion involves the conceptual design synthesis program used for High Speed Civil Transport (HSCT) studies, ACSYNT (aircraft synthesis), and enhancements that have been made especially for HSRP. Some results are presented for one study that has been completed and two that are underway. These are the advanced controls integration study, the fuel cost impact study, and the oblique wing configuration evaluation that is part of a larger innovative concepts study.

Low body temperature in long-lived Ames dwarf mice at rest and during stress.

Science.gov (United States)

Hunter, W S; Croson, W B; Bartke, A; Gentry, M V; Meliska, C J

1999-09-01

Among homeothermic animals, larger species generally have lower metabolic rates and live longer than do smaller species. Because Ames dwarf mice (dwarfs) live approximately 1 year longer than their larger normal sex- and age-matched siblings (normals), we hypothesized that they would have lower body core temperature (Tco). We, therefore, measured Tco of six dwarfs and six normals during 24-h periods of ad lib feeding, 24-h food deprivation, and emotional stress induced by cage switching. With ad lib feeding, Tco of dwarfs averaged 1.6 degrees C lower than normals; during food deprivation, Tco of both dwarfs and controls was significantly lower than when food was available ad lib; and following cage switch, Tco was elevated in both groups. However, during all three experiments, Tco was significantly lower in dwarfs than in normals. These data support the hypothesis that Ames dwarf mice, which live longer than normal size controls, maintain lower Tco than normals. Because dwarfs are deficient in thyroid stimulating hormone (TSH) and growth hormone (GH), their low Tco may be a result of reduced thermogenesis due to lack of those hormones. However, whether low Tco per se is related to the increased longevity of the dwarf mice remains an interesting possibility to be investigated.

Estonia purjetab filmiturule / Jüri Laulik

Index Scriptorium Estoniae

Laulik, Jüri, 1959-

2003-01-01

Saksamaal Berliinis esilinastub pidulikult 13. oktoobril poliitiline põnevusfilm "Balti torm" ("Baltic Storm"), mis kujutab parvlaev "Estonia" hukku. Režissöör ja üks stsenariste on Reuben Leder, peaosades Greta Scacchi ja Jürgen Prochnow. Kaasa teeb ka Donald Sutherland USA kindrali rollis. Eesti näitlejaist teeb kaasa Rein Oja

Applied Computational Fluid Dynamics at NASA Ames Research Center

Science.gov (United States)

Holst, Terry L.; Kwak, Dochan (Technical Monitor)

1994-01-01

The field of Computational Fluid Dynamics (CFD) has advanced to the point where it can now be used for many applications in fluid mechanics research and aerospace vehicle design. A few applications being explored at NASA Ames Research Center will be presented and discussed. The examples presented will range in speed from hypersonic to low speed incompressible flow applications. Most of the results will be from numerical solutions of the Navier-Stokes or Euler equations in three space dimensions for general geometry applications. Computational results will be used to highlight the presentation as appropriate. Advances in computational facilities including those associated with NASA's CAS (Computational Aerosciences) Project of the Federal HPCC (High Performance Computing and Communications) Program will be discussed. Finally, opportunities for future research will be presented and discussed. All material will be taken from non-sensitive, previously-published and widely-disseminated work.

How to write an educational research grant: AMEE Guide No. 101.

Science.gov (United States)

Blanco, Maria A; Gruppen, Larry D; Artino, Anthony R; Uijtdehaage, Sebastian; Szauter, Karen; Durning, Steven J

2016-01-01

Writing an educational research grant in health profession education is challenging, not only for those doing it for the first time but also for more experienced scholars. The intensity of the competition, the peculiarities of the grant format, the risk of rejection, and the time required are among the many obstacles that can prevent educational researchers with interesting and important ideas from writing a grant, that could provide the funding needed to turn their scholarly ideas into reality. The aim of this AMEE Guide is to clarify the grant-writing process by (a) explaining the mechanics and structure of a typical educational research grant proposal, and (b) sharing tips and strategies for making the process more manageable.

Ames Mutagenicity Assessment of Flavored Water Pipe Tobacco Products :A Cross Sectional Study in Tehran

Directory of Open Access Journals (Sweden)

Shahrzad Sadri

2016-12-01

Full Text Available Waterpipe smoking has become a global youth trend especially in the Middle East countries and Iran . The aim of this study was to determine the mutagenic effects of three most popular flavored tobaccos by four different salmonella typhimurium strains and compare the possible mutagenic effects of the test samples. Ames mutagenicity assessment was conducted according to the OECD guideline using TA100, TA98 , YG1024 and YG1029 strains. Charcoal burned flavored tobaccos of three different flavors including Orange, Double Apple, and Lime Mint were filtered and exposed to all strains after strain identification tests and MIC ,MBC determinations. The Ames test results indicated significant mutagenic effects of tobacco samples in all four test strains when compared with negative control (p≤0.0001. The highest Mutagenic Factor (MF was seen in Double Apple samples using TA 98 (MF=11.5±3.3 . In all experiments, TA strains showed higher sensitivity to the samples than YG strains which suggest these two strains for further regulatory toxicity tests ,policy making purposes and tobacco control programs . Present results represents an important step in understanding the genotoxic potentials of three most popular flavored tobaccos samples of a famous brand in the global markets .

Uji Mutagenik Ames untuk Melengkapi Data Keamanan Ekstrak Gambir (Uncaria gambir Roxb.

Directory of Open Access Journals (Sweden)

Novi Sulistyaningrum

2015-05-01

Full Text Available The main compound of Uncaria gambir Roxb. (gambir, catechin and it’s derivates have been believed to be potential as antiviral. Epigallocatechin gallate (EGCG and epicatechin are catechin derivates which are found to be potential as antiviral against Human Immunodeficiency Virus (HIV. However, gambir extract also contains quercetin that has possibility to be mutagenic. Therefore, a preliminary study towards safety of those compounds within gambir extract, mutagenicity assay using Ames Method has been performed.Sample (gambir extract was obtained from West Sumatera, Indonesia. The extract was characterized according to Farmakope Herbal Indonesia and WHO methods. Mutagenicity test by Ames method utilized a colorimetric microplate in 6 various concentration (125 mg/mL; 62.5 mg/mL; 31.25 mg/mL; 15.625 mg/mL; 7.81 mg/mL dan 3.91 mg/mL against mutant bacteria Salmonella typhimurium TA 98, Salmonella typhimurium TA 100 and Escherichia coli WP2 uvrA with and without the addition of S-9 enzyme. Extract of gambir in this study contains 86.60% of catechin, 12.92% moisture content, 22.49% water-soluble extract content, 80.63% ethanol-soluble extract content, 0.81% total ash, 0.32% acid insoluble ash content and 10.38% in dryness level. From the mutagenicity test and calculation, fold increase (over baseline of the sample in 6 various concentration with and without adding S-9 enzyme are lower than 2. Gambir extract from West Sumatra with catechin contains 86.6% hasn’t showed mutagenic effect due to the fold increase (over baseline of mutagenicity test lower than 2.

Ames dwarf (Prop1(df)/Prop1(df)) mice display increased sensitivity of the major GH-signaling pathways in liver and skeletal muscle.

Science.gov (United States)

Miquet, Johanna G; Muñoz, Marina C; Giani, Jorge F; González, Lorena; Dominici, Fernando P; Bartke, Andrzej; Turyn, Daniel; Sotelo, Ana I

2010-04-01

Growth hormone (GH) is an anabolic hormone that regulates growth and metabolism. Ames dwarf mice are natural mutants for Prop1, with impaired development of anterior pituitary and undetectable levels of circulating GH, prolactin and TSH. They constitute an endocrine model of life-long GH-deficiency. The main signaling cascades activated by GH binding to its receptor are the JAK2/STATs, PI-3K/Akt and the MAPK Erk1/2 pathways. We have previously reported that GH-induced STAT5 activation was higher in Ames dwarf mice liver compared to non-dwarf controls. The aim of this study was to evaluate the principal components of the main GH-signaling pathways under GH-deficiency in liver and skeletal muscle, another GH-target tissue. Ames dwarf mice and their non-dwarf siblings were assessed. Animals were injected i.p. with GH or saline 15min before tissue removal. Protein content and phosphorylation of signaling mediators were determined by immunoblotting of tissue solubilizates. GH was able to induce STAT5 and STAT3 tyrosine phosphorylation in both liver and muscle, but the response was higher for Ames dwarf mice than for non-dwarf controls. When Erk1/2 activation was assessed in liver, only dwarf mice showed GH-induced phosphorylation, while in muscle no response to the hormone was found in either genotype. GH-induced Akt phosphorylation at Ser473 in liver was only detected in dwarf mice. In skeletal muscle, both normal and dwarf mice responded to a GH stimulus, although dwarf mice presented higher GH activation levels. The phosphorylation of GSK-3, a substrate of Akt, increased upon hormone stimulation only in dwarf mice in both tissues. In contrast, no differences in the phosphorylation of mTOR, another substrate of Akt, were observed after GH stimulus, either in normal or dwarf mice in liver, while we were unable to determine mTOR in muscle. Protein content of GH-receptor and of the signaling mediators studied did not vary between normal and dwarf animals in the assessed

Tõelise ordenisaju ootel / Igor Gräzin

Index Scriptorium Estoniae

Gräzin, Igor, 1952-

2007-01-01

Riigikogus on arutusel uus teenetemärkide seaduse eelnõu, mis võimaldab ordeneid vääritute inimeste käest hiljem ära võtta. See teeb autasu andmise presidendi jaoks intellektuaalselt veel raskemaks. Autor teeb ettepaneku pärast 2008. a. veebruari lõpetada mis tahes tsiviilordenite andmine Eesti Vabariigis. Ilmunud ka: Vesti Dnja 18. dets. 2007, lk. 5

Estonia ujub Saksamaa kinodesse / Andres Laasik, Heiki Suurkask

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2003-01-01

Saksamaal Berliinis esilinastub pidulikult 13. oktoobril poliitiline põnevusfilm "Balti torm" ("Baltic Storm"), mis kujutab parvlaev "Estonia" hukku. Režissöör ja üks stsenariste on Reuben Leder, peaosades Greta Scacchi ja Jürgen Prochnow. Kaasa teeb ka Donald Sutherland USA kindrali rollis. Eesti näitlejaist teeb kaasa Rein Oja. Põhjamaades on filmi linastamine kahtluse all

Early management of sepsis with emphasis on early goal directed therapy: AME evidence series 002

OpenAIRE

Zhang, Zhongheng; Hong, Yucai; Smischney, Nathan J.; Kuo, Han-Pin; Tsirigotis, Panagiotis; Rello, Jordi; Kuan, Win Sen; Jung, Christian; Robba, Chiara; Taccone, Fabio Silvio; Leone, Marc; Spapen, Herbert; Grimaldi, David; Van Poucke, Sven; Simpson, Steven Q.

2017-01-01

Severe sepsis and septic shock are major causes of morbidity and mortality in patients entering the emergency department (ED) or intensive care unit (ICU). Despite substantial efforts to improve patient outcome, treatment of sepsis remains challenging to clinicians. In this context, early goal directed therapy (EGDT) represents an important concept emphasizing both early recognition of sepsis and prompt initiation of a structured treatment algorithm. As part of the AME evidence series on seps...

When is a search not a search? A comparison of searching the AMED complementary health database via EBSCOhost, OVID and DIALOG.

Science.gov (United States)

Younger, Paula; Boddy, Kate

2009-06-01

The researchers involved in this study work at Exeter Health library and at the Complementary Medicine Unit, Peninsula School of Medicine and Dentistry (PCMD). Within this collaborative environment it is possible to access the electronic resources of three institutions. This includes access to AMED and other databases using different interfaces. The aim of this study was to investigate whether searching different interfaces to the AMED allied health and complementary medicine database produced the same results when using identical search terms. The following Internet-based AMED interfaces were searched: DIALOG DataStar; EBSCOhost and OVID SP_UI01.00.02. Search results from all three databases were saved in an endnote database to facilitate analysis. A checklist was also compiled comparing interface features. In our initial search, DIALOG returned 29 hits, OVID 14 and Ebsco 8. If we assume that DIALOG returned 100% of potential hits, OVID initially returned only 48% of hits and EBSCOhost only 28%. In our search, a researcher using the Ebsco interface to carry out a simple search on AMED would miss over 70% of possible search hits. Subsequent EBSCOhost searches on different subjects failed to find between 21 and 86% of the hits retrieved using the same keywords via DIALOG DataStar. In two cases, the simple EBSCOhost search failed to find any of the results found via DIALOG DataStar. Depending on the interface, the number of hits retrieved from the same database with the same simple search can vary dramatically. Some simple searches fail to retrieve a substantial percentage of citations. This may result in an uninformed literature review, research funding application or treatment intervention. In addition to ensuring that keywords, spelling and medical subject headings (MeSH) accurately reflect the nature of the search, database users should include wildcards and truncation and adapt their search strategy substantially to retrieve the maximum number of appropriate

Valmis film parvlaev Estonia katastroofist / Imre Kaas

Index Scriptorium Estoniae

Kaas, Imre

2003-01-01

Saksamaal on valminud poliitiline põnevusfilm "Balti torm" ("Baltic Storm"), mis kujutab parvlaev "Estonia" hukku venelaste vandenõu tulemusena. Film jõuab Eestis linale novembri alul. Produtsent ja esialgse stsenaariumi autor koosHenning Wittega on Jutta Rabe, režissöör ja üks stsenariste Reuben Leder. Kaasa teeb ka Donald Sutherland USA kindrali rollis. Eesti näitlejaist teeb kaasa Rein Oja

Phenotypic Data Collection and Sample Preparation for Genomics of Wood Formation and Cellulosic Biomass Traits in Sunflower: Ames, IA location.

Energy Technology Data Exchange (ETDEWEB)

Marek, Laura F.

2011-06-17

Three fields were planted in Ames in 2010, two association mapping fields, N3 and A, and a recombinant inbred line field, N13. Phenotype data and images were transferred to UGA to support genetic and genomic analyses of woody biomass-related traits.

NASA Ames Research Center 60 MW Power Supply Modernization

Science.gov (United States)

Choy, Yuen Ching; Ilinets, Boris V.; Miller, Ted; Nagel, Kirsten (Technical Monitor)

2001-01-01

The NASA Ames Research Center 60 MW DC Power Supply was built in 1974 to provide controlled DC power for the Thermophysics Facility Arc Jet Laboratory. The Power Supply has gradually losing reliability due to outdated technology and component life limitation. NASA has decided to upgrade the existing rectifier modules with contemporary high-power electronics and control equipment. NASA plans to complete this project in 2001. This project includes a complete replacement of obsolete thyristor stacks in all six rectifier modules and rectifier bridge control system. High power water-cooled thyristors and freewheeling diodes will be used. The rating of each of the six modules will be 4000 A at 5500 V. The control firing angle signal will be sent from the Facility Control System to six modules via fiberoptic cable. The Power Supply control and monitoring system will include a Master PLC in the Facility building and a Slave PLC in each rectifier module. This system will also monitor each thyristor level in each stack and the auxiliary equipment.

Prominent transverse flow of clusters in stopped Au(150AMeV)+Au reactions

International Nuclear Information System (INIS)

Coffin, J.P.; Kuhn, C.; Roy, C.; Cerruti, C.; Crochet, P.; Fintz, P.; Guillaume, G.; Houari, A.; Jundt, F.; Rami, F.; Tizniti, L.; Wagner, P.; Konopka, J.; Stoecker, H.

1995-01-01

Stopped Au(150AMeV)+Au collisions have been measured with the FOPI-Detector at GSI by imposing an upper limit on the ratio of the global longitudinal momentum to the collected charge within an event. The ejectiles, in particular those with Z>3, have a rapidity close to mid-rapidity and exhibit angular distributions in the centre-of-mass strongly peaking around 90 thus suggesting an enhancement of the flow in the transverse direction. Fits to the data and comparisons with QMD calculations indicate an averaged collective velocity in the transverse direction equal to 0.12c. Significance of the determined velocity and temperature values is discussed. ((orig.))

Preliminary data from lithium hydride ablation tests conducted by NASA, Ames Research Center

International Nuclear Information System (INIS)

Elliott, R.D.

1970-01-01

A series of ablation tests of lithium hydride has been made by NASA-Ames in one of their high-enthalpy arc-heated wind tunnels. Two-inch diameter cylindrical samples of the hydride, supplied by A. I., were subjected to heating on their ends for time periods up to 10 seconds. After each test, the amount of material removed from each sample was measured. The rates of loss of material were correlated with the heat input rates in terms of a heat of ablation, which ranged from 2100 to 3500 Btu/lb. The higher values were obtained when the hydride contained a matrix such as steel honeycomb of steel wool. (U.S.)

Application of satellite data to the studies of agricultural meteorology: Relationship between ground temperature from GMS IR data and AMeDAS air temperature

International Nuclear Information System (INIS)

Tani, H.; Horiguchi, I.; Motoki, T.

1984-01-01

The purpose of the present study is to estimate air temperature in areas where there is no meteorological observation site, using satellite thermal IR data. Surface temperature from GMS IR data derived by eq. (1) was compared with AMeDAS (meteorological observation site) air temperature. The results are summarized as follows: 1) The maximum correlation coefficients between AMeDAS air temperature and surface temperature from GMS IR data is 0.90, the minimum is 0.30 and the mean is 0.60±0.15. 2) The correlation coefficients are affected by the precipitable water and decrease with increasing precipitable Water as shown in Fig. 2. 3) The correlation coefficients for each GMS observed time are better at night and in the morning than during the day (Table 2). 4) Also, the small values of the regression coefficients appear during the day and the large values at night and in the morning (Table 2). 5) The standard deviations which indicated scattering around the regression line are large at 12:00 and 15:00, but small at 06:00 and 09:00 (Table 2). The reason that correlation coefficients, regression coefficients and standard deviations between AMeDAS air temperature and surface temperature from GMS IR data are less during the day than at night and in the morning, is caused by ground conditions because the effects of solar radiation on surface temperature depend on ground surface conditions: plant cover, incline of slope etc. The hourly mean deviation from the regression line for surface temperature was calculated to investigate the characteristic of ground surface conditions for each AMeDAS observation site. AMeDAS observation sites were classified into four types according to the patterns of the hourly mean deviation as shown in Fig. 5. Most of type I were distributed in the plain regions: Ishikari, Konsen and Tokachi. Type II appears in the basin regions and type III on the coast of the Pacific Ocean and the Sea of Okhotsuk. The remaining areas are type IV. The standard

THE NASA AMES POLYCYCLIC AROMATIC HYDROCARBON INFRARED SPECTROSCOPIC DATABASE: THE COMPUTED SPECTRA

International Nuclear Information System (INIS)

Bauschlicher, C. W.; Ricca, A.; Boersma, C.; Mattioda, A. L.; Cami, J.; Peeters, E.; Allamandola, L. J.; Sanchez de Armas, F.; Puerta Saborido, G.; Hudgins, D. M.

2010-01-01

The astronomical emission features, formerly known as the unidentified infrared bands, are now commonly ascribed to polycyclic aromatic hydrocarbons (PAHs). The laboratory experiments and computational modeling done at the NASA Ames Research Center to create a collection of PAH IR spectra relevant to test and refine the PAH hypothesis have been assembled into a spectroscopic database. This database now contains over 800 PAH spectra spanning 2-2000 μm (5000-5 cm -1 ). These data are now available on the World Wide Web at www.astrochem.org/pahdb. This paper presents an overview of the computational spectra in the database and the tools developed to analyze and interpret astronomical spectra using the database. A description of the online and offline user tools available on the Web site is also presented.

Genotoxic and cytotoxic potential of whole plant extracts of Kalanchoe laciniata by Ames and MTT assay.

Science.gov (United States)

Sharif, Ali; Akhtar, Muhammad Furqan; Akhtar, Bushra; Saleem, Ammara; Manan, Maria; Shabbir, Maryam; Ashraf, Muneeb; Peerzada, Sohaib; Ahmed, Shoaib; Raza, Moosa

2017-01-01

Lack of data on safety of herbal medicines have endangered human health and life. The present study evaluated the genotoxic and mutagenic effect of Kalanchoe laciniata to access the safety and usefulness of the medicinal plant. Aqua-methanolic and n-hexane extracts of K. laciniata were evaluated for the genotoxic potential using Ames assay and cytotoxicity was evaluated using MTT assay. Ames assay was conducted using two strains of Salmonella typhimurium TA-100 and TA-102 whereas MTT assay was performed on baby hamster kidney cell line BHK-21. Aqua-methanolic extract of K. laciniata exhibited significant mutagenicity when exposed to TA-102 strain with a mutagenic index of 50.66 and 54.74 at maximum dose 150 mg/plate. The extract was also mutagenic to TA-100 strain but to a lesser extent. M.I of n-hexane extract was 12.15 and 15.51 for TA-100 and TA-102 respectively. n-hexane extract was mutagenic but little difference was observed between results of two strains. Both extracts were found to be cytotoxic with an IC 50 of 321.9 and 638.5 µg/mL for aqua-methanolic and n-hexane extracts respectively. On the basis of results it was concluded that aqua-methanolic and n-hexane extracts of K. laciniata possess mutagenic and cytotoxic potential. It is suggested to explore the plant further to evaluate its safety in rodents and other species.

Experiences with a high-blockage model tested in the NASA Ames 12-foot pressure wind tunnel

Science.gov (United States)

Coder, D. W.

1984-01-01

Representation of the flow around full-scale ships was sought in the subsonic wind tunnels in order to a Hain Reynolds numbers as high as possible. As part of the quest to attain the largest possible Reynolds number, large models with high blockage are used which result in significant wall interference effects. Some experiences with such a high blockage model tested in the NASA Ames 12-foot pressure wind tunnel are summarized. The main results of the experiment relating to wind tunnel wall interference effects are also presented.

The effects of alcohol mixed with energy drink (AMED) on subjective intoxication and alertness : results from a double-blind placebo-controlled clinical trial

NARCIS (Netherlands)

van de Loo, Aurora J A E; van Andel, Nienke; van Gelder, Charlotte A G H; Janssen, Boris S G; Titulaer, Joep; Jansen, Jimmy; Verster, Joris C

2016-01-01

OBJECTIVE: The purpose of this double blind placebo controlled study was to examine if specific effects on subjective intoxication and alertness-sleepiness ratings could be demonstrated after consuming alcohol mixed with energy drink (AMED) when compared to consuming alcohol only (AO). METHODS: 56

Mobile technologies in medical education: AMEE Guide No. 105.

Science.gov (United States)

Masters, Ken; Ellaway, Rachel H; Topps, David; Archibald, Douglas; Hogue, Rebecca J

2016-06-01

Mobile technologies (including handheld and wearable devices) have the potential to enhance learning activities from basic medical undergraduate education through residency and beyond. In order to use these technologies successfully, medical educators need to be aware of the underpinning socio-theoretical concepts that influence their usage, the pre-clinical and clinical educational environment in which the educational activities occur, and the practical possibilities and limitations of their usage. This Guide builds upon the previous AMEE Guide to e-Learning in medical education by providing medical teachers with conceptual frameworks and practical examples of using mobile technologies in medical education. The goal is to help medical teachers to use these concepts and technologies at all levels of medical education to improve the education of medical and healthcare personnel, and ultimately contribute to improved patient healthcare. This Guide begins by reviewing some of the technological changes that have occurred in recent years, and then examines the theoretical basis (both social and educational) for understanding mobile technology usage. From there, the Guide progresses through a hierarchy of institutional, teacher and learner needs, identifying issues, problems and solutions for the effective use of mobile technology in medical education. This Guide ends with a brief look to the future.

X-ray K-edge analysis of drain lines in Wilhelm Hall, Ames Laboratory

International Nuclear Information System (INIS)

Jensen, T.; Whitmore, C.; Iowa State Univ., Ames, IA

1999-01-01

From August 12--27, 1998 X-ray K-edge measurements were made on drain lines in seven rooms in Wilhelm Hall, Ames Laboratory. The purpose of these measurements was to determine the extent of thorium (and other heavy metal) contamination inside these pipes. The K-edge method is a noninvasive inspection technique that can provide accurate quantification of heavy metal contamination interior to an object. Of the seven drain lines inspected, one was found to have no significant contamination, three showed significant thorium deposits, two showed mercury contamination, and one line was found to contain mercury, thorium and uranium. The K-edge measurements were found to be consistent with readings from hand-held survey meters, and provided much greater detail on the location and amount of heavy metal contamination

Development and operation of a real-time simulation at the NASA Ames Vertical Motion Simulator

Science.gov (United States)

Sweeney, Christopher; Sheppard, Shirin; Chetelat, Monique

1993-01-01

The Vertical Motion Simulator (VMS) facility at the NASA Ames Research Center combines the largest vertical motion capability in the world with a flexible real-time operating system allowing research to be conducted quickly and effectively. Due to the diverse nature of the aircraft simulated and the large number of simulations conducted annually, the challenge for the simulation engineer is to develop an accurate real-time simulation in a timely, efficient manner. The SimLab facility and the software tools necessary for an operating simulation will be discussed. Subsequent sections will describe the development process through operation of the simulation; this includes acceptance of the model, validation, integration and production phases.

In vitro mutagenicity assay (Ames test and phytochemical characterization of seeds oil of Helianthus annuus Linné (sunflower

Directory of Open Access Journals (Sweden)

Nelma de Mello Silva Oliveira

Full Text Available The objective of this research was to investigate the genotoxic potential of the oil of H. annuus L. (sunflower seeds via the Ames test as well as its oxidative properties and lipid composition. The pre-incubation method, system metabolic activation (S9 fraction and five S. typhimurium strains (TA97, TA98, TA100, TA1535 and TA102 were employed for the Ames test. The oxidative stability and fatty acid composition were analyzed by standard methods and gas chromatography. A revertant analysis showed no significant differences between the treatment doses (10–200 μl/plate and the negative controls, regardless of S9+ and S9−, and included all of the S. typhimurium strains. Chromatographic analysis showed high levels of polyunsaturated fatty acids, followed by monounsaturated, saturated and total trans-isomers. Among the polyunsaturated, monounsaturated and saturated fatty acids, linoleic, oleic and palmitic acids predominated. The results suggest that the sunflower oil is not genotoxic as indicated by frameshift mutations and base pair substitutions regardless of the treatment dose, but shows dose-dependent toxicity. The oxidative properties of the sunflower oil were consistent with the requirements of national and international standards. However, its composition could also indicate phytotherapeutic properties. Keywords: Helianthus annuus L., Sunflower oil, Genetic toxicity, Gas chromatography

Low-speed tests of a high-aspect-ratio, supercritical-wing transport model equipped with a high-lift flap system in the Langley 4- by 7-meter and Ames 12-foot pressure tunnels

Science.gov (United States)

Morgan, H. L., Jr.; Kjelgaard, S. O.

1983-01-01

The Ames 12-Foot Pressure Tunnel was used to determine the effects of Reynolds number on the static longitudinal aerodynamic characteristics of an advanced, high-aspect-ratio, supercritical wing transport model equipped with a full span, leading edge slat and part span, double slotted, trailing edge flaps. The model had a wing span of 7.5 ft and was tested through a free stream Reynolds number range from 1.3 to 6.0 x 10 to 6th power per foot at a Mach number of 0.20. Prior to the Ames tests, an investigation was also conducted in the Langley 4 by 7 Meter Tunnel at a Reynolds number of 1.3 x 10 to 6th power per foot with the model mounted on an Ames strut support system and on the Langley sting support system to determine strut interference corrections. The data obtained from the Langley tests were also used to compare the aerodynamic charactertistics of the rather stiff, 7.5-ft-span steel wing model tested during this investigation and the larger, and rather flexible, 12-ft-span aluminum-wing model tested during a previous investigation. During the tests in both the Langley and Ames tunnels, the model was tested with six basic wing configurations: (1) cruise; (2) climb (slats only extended); (3) 15 deg take-off flaps; (4) 30 deg take-off flaps; (5) 45 deg landing flaps; and (6) 60 deg landing flaps.

Reduction of Background Noise in the NASA Ames 40- by 80-Foot Wind Tunnel

Science.gov (United States)

Jaeger, Stephen M.; Allen, Christopher S.; Soderman, Paul T.; Olson, Larry E. (Technical Monitor)

1995-01-01

Background noise in both open-jet and closed wind tunnels adversely affects the signal-to-noise ratio of acoustic measurements. To measure the noise of increasingly quieter aircraft models, the background noise will have to be reduced by physical means or through signal processing. In a closed wind tunnel, such as the NASA Ames 40- by 80- Foot Wind Tunnel, the principle background noise sources can be classified as: (1) fan drive noise; (2) microphone self-noise; (3) aerodynamically induced noise from test-dependent hardware such as model struts and junctions; and (4) noise from the test section walls and vane set. This paper describes the steps taken to minimize the influence of each of these background noise sources in the 40 x 80.

New Diagnostic, Launch and Model Control Techniques in the NASA Ames HFFAF Ballistic Range

Science.gov (United States)

Bogdanoff, David W.

2012-01-01

This report presents new diagnostic, launch and model control techniques used in the NASA Ames HFFAF ballistic range. High speed movies were used to view the sabot separation process and the passage of the model through the model splap paper. Cavities in the rear of the sabot, to catch the muzzle blast of the gun, were used to control sabot finger separation angles and distances. Inserts were installed in the powder chamber to greatly reduce the ullage volume (empty space) in the chamber. This resulted in much more complete and repeatable combustion of the powder and hence, in much more repeatable muzzle velocities. Sheets of paper or cardstock, impacting one half of the model, were used to control the amplitudes of the model pitch oscillations.

Isospin influence on the decay modes of compound systems produced in the 78,86Kr + 40,48Ca at 10 AMeV

Directory of Open Access Journals (Sweden)

Pirrone S.

2016-01-01

Full Text Available The study of the decay modes competition of the compound systems produced in the collisions 78Kr+40Ca and 86Kr+48Ca at 10AMeV is presented. In particular, the N/Z entrance channel influence on the decay paths of the compound systems, directly connected to the isospin influence, is investigated. The experiment was performed at the INFN Laboratori Nazionali del Sud (LNS in Catania by using the 4π multi-detector CHIMERA. Charge, mass, angular distributions and kinematical features of the reaction products were studied. The analysis shows some differences in the contribution arising from the various reaction mechanisms for the neutron poor and neutron rich systems. Comparison with theoretical statistical and dynamical models are presented for the two systems. Besides a study of the influence of the energy on the entrance channel is performed for the 78Kr+40Ca reaction, by comparing the results of this experiment to those obtained for the same system at 5.5 AMeV with the INDRA device at GANIL.

Ethnography in qualitative educational research: AMEE Guide No. 80.

Science.gov (United States)

Reeves, Scott; Peller, Jennifer; Goldman, Joanne; Kitto, Simon

2013-08-01

Ethnography is a type of qualitative research that gathers observations, interviews and documentary data to produce detailed and comprehensive accounts of different social phenomena. The use of ethnographic research in medical education has produced a number of insightful accounts into its role, functions and difficulties in the preparation of medical students for clinical practice. This AMEE Guide offers an introduction to ethnography - its history, its differing forms, its role in medical education and its practical application. Specifically, the Guide initially outlines the main characteristics of ethnography: describing its origins, outlining its varying forms and discussing its use of theory. It also explores the role, contribution and limitations of ethnographic work undertaken in a medical education context. In addition, the Guide goes on to offer a range of ideas, methods, tools and techniques needed to undertake an ethnographic study. In doing so it discusses its conceptual, methodological, ethical and practice challenges (e.g. demands of recording the complexity of social action, the unpredictability of data collection activities). Finally, the Guide provides a series of final thoughts and ideas for future engagement with ethnography in medical education. This Guide is aimed for those interested in understanding ethnography to develop their evaluative skills when reading such work. It is also aimed at those interested in considering the use of ethnographic methods in their own research work.

The NASA Ames Research Center Institutional Scientific Collection: History, Best Practices and Scientific Opportunities

Science.gov (United States)

Rask, Jon C.; Chakravarty, Kaushik; French, Alison; Choi, Sungshin; Stewart, Helen

2017-01-01

The NASA Ames Life Sciences Institutional Scientific Collection (ISC), which is composed of the Ames Life Sciences Data Archive (ALSDA) and the Biospecimen Storage Facility (BSF), is managed by the Space Biosciences Division and has been operational since 1993. The ALSDA is responsible for archiving information and animal biospecimens collected from life science spaceflight experiments and matching ground control experiments. Both fixed and frozen spaceflight and ground tissues are stored in the BSF within the ISC. The ALSDA also manages a Biospecimen Sharing Program, performs curation and long-term storage operations, and makes biospecimens available to the scientific community for research purposes via the Life Science Data Archive public website (https:lsda.jsc.nasa.gov). As part of our best practices, a viability testing plan has been developed for the ISC, which will assess the quality of archived samples. We expect that results from the viability testing will catalyze sample use, enable broader science community interest, and improve operational efficiency of the ISC. The current viability test plan focuses on generating disposition recommendations and is based on using ribonucleic acid (RNA) integrity number (RIN) scores as a criteria for measurement of biospecimen viablity for downstream functional analysis. The plan includes (1) sorting and identification of candidate samples, (2) conducting a statiscally-based power analysis to generate representaive cohorts from the population of stored biospecimens, (3) completion of RIN analysis on select samples, and (4) development of disposition recommendations based on the RIN scores. Results of this work will also support NASA open science initiatives and guides development of the NASA Scientific Collections Directive (a policy on best practices for curation of biological collections). Our RIN-based methodology for characterizing the quality of tissues stored in the ISC since the 1980s also creates unique

Development of Implicit Methods in CFD NASA Ames Research Center 1970's - 1980's

Science.gov (United States)

Pulliam, Thomas H.

2010-01-01

The focus here is on the early development (mid 1970's-1980's) at NASA Ames Research Center of implicit methods in Computational Fluid Dynamics (CFD). A class of implicit finite difference schemes of the Beam and Warming approximate factorization type will be addressed. The emphasis will be on the Euler equations. A review of material pertinent to the solution of the Euler equations within the framework of implicit methods will be presented. The eigensystem of the equations will be used extensively in developing a framework for various methods applied to the Euler equations. The development and analysis of various aspects of this class of schemes will be given along with the motivations behind many of the choices. Various acceleration and efficiency modifications such as matrix reduction, diagonalization and flux split schemes will be presented.

Updates on Modeling the Water Cycle with the NASA Ames Mars Global Climate Model

Science.gov (United States)

Kahre, M. A.; Haberle, R. M.; Hollingsworth, J. L.; Montmessin, F.; Brecht, A. S.; Urata, R.; Klassen, D. R.; Wolff, M. J.

2017-01-01

Global Circulation Models (GCMs) have made steady progress in simulating the current Mars water cycle. It is now widely recognized that clouds are a critical component that can significantly affect the nature of the simulated water cycle. Two processes in particular are key to implementing clouds in a GCM: the microphysical processes of formation and dissipation, and their radiative effects on heating/ cooling rates. Together, these processes alter the thermal structure, change the dynamics, and regulate inter-hemispheric transport. We have made considerable progress representing these processes in the NASA Ames GCM, particularly in the presence of radiatively active water ice clouds. We present the current state of our group's water cycle modeling efforts, show results from selected simulations, highlight some of the issues, and discuss avenues for further investigation.­

A critical review of the life sciences project management at Ames Research Center for the Spacelab Mission development test 3

Science.gov (United States)

Helmreich, R. L.; Wilhelm, J. M.; Tanner, T. A.; Sieber, J. E.; Burgenbauch, S. F.

1979-01-01

A management study was initiated by ARC (Ames Research Center) to specify Spacelab Mission Development Test 3 activities and problems. This report documents the problems encountered and provides conclusions and recommendations to project management for current and future ARC life sciences projects. An executive summary of the conclusions and recommendations is provided. The report also addresses broader issues relevant to the conduct of future scientific missions under the constraints imposed by the space environment.

Model Deformation and Optical Angle of Attack Measurement System in the NASA Ames Unitary Plan Wind Tunnel

Science.gov (United States)

Kushner, Laura K.; Drain, Bethany A.; Schairer, Edward T.; Heineck, James T.; Bell, James H.

2017-01-01

Both AoA and MDM measurements can be made using an optical system that relies on photogrammetry. Optical measurements are being requested by customers in wind tunnels with increasing frequency due to their non-intrusive nature and recent hardware and software advances that allow measurements to become near real time. The NASA Ames Research Center Unitary Plan Wind Tunnel is currently developing a system based on photogrammetry to measure model deformation and model angle of attack. This paper describes the new system, its development, its use on recent tests and plans to further develop the system.

Critical review of Ames Life Science participation in Spacelab Mission Development Test 3: The SMD 3 management study

Science.gov (United States)

Helmreich, R.; Wilhelm, J.; Tanner, T. A.; Sieber, J. E.; Burgenbauch, S.

1978-01-01

A management study was conducted to specify activities and problems encountered during the development of procedures for documentation and crew training on experiments, as well as during the design, integration, and delivery of a life sciences experiment payload to Johnson Space Center for a 7 day simulation of a Spacelab mission. Conclusions and recommendations to project management for current and future Ames' life sciences projects are included. Broader issues relevant to the conduct of future scientific missions under the constraints imposed by the environment of space are also addressed.

Performance of the OVERFLOW-MLP and LAURA-MLP CFD Codes on the NASA Ames 512 CPU Origin System

Science.gov (United States)

Taft, James R.

2000-01-01

The shared memory Multi-Level Parallelism (MLP) technique, developed last year at NASA Ames has been very successful in dramatically improving the performance of important NASA CFD codes. This new and very simple parallel programming technique was first inserted into the OVERFLOW production CFD code in FY 1998. The OVERFLOW-MLP code's parallel performance scaled linearly to 256 CPUs on the NASA Ames 256 CPU Origin 2000 system (steger). Overall performance exceeded 20.1 GFLOP/s, or about 4.5x the performance of a dedicated 16 CPU C90 system. All of this was achieved without any major modification to the original vector based code. The OVERFLOW-MLP code is now in production on the inhouse Origin systems as well as being used offsite at commercial aerospace companies. Partially as a result of this work, NASA Ames has purchased a new 512 CPU Origin 2000 system to further test the limits of parallel performance for NASA codes of interest. This paper presents the performance obtained from the latest optimization efforts on this machine for the LAURA-MLP and OVERFLOW-MLP codes. The Langley Aerothermodynamics Upwind Relaxation Algorithm (LAURA) code is a key simulation tool in the development of the next generation shuttle, interplanetary reentry vehicles, and nearly all "X" plane development. This code sustains about 4-5 GFLOP/s on a dedicated 16 CPU C90. At this rate, expected workloads would require over 100 C90 CPU years of computing over the next few calendar years. It is not feasible to expect that this would be affordable or available to the user community. Dramatic performance gains on cheaper systems are needed. This code is expected to be perhaps the largest consumer of NASA Ames compute cycles per run in the coming year.The OVERFLOW CFD code is extensively used in the government and commercial aerospace communities to evaluate new aircraft designs. It is one of the largest consumers of NASA supercomputing cycles and large simulations of highly resolved full

Comparison of acoustic data from a 102 mm conic nozzle as measured in the RAE 24-foot wind tunnel and the NASA Ames 40- by 80-foot wind tunnel

Science.gov (United States)

Atencio, A., Jr.; Mckie, J.

1982-01-01

A cooperative program between the Royal Aircraft Establishment (RAE), England, and the NASA Ames Research Center was initiated to compare acoustic measurements made in the RAE 24-foot wind tunnel and in the Ames 40- by 80-foot wind tunnel. The acoustic measurements were made in both facilities using the same 102 mm conical nozzle supplied by the RAE. The nozzle was tested by each organization using its respective jet test rig. The mounting hardware and nozzle exit conditions were matched as closely as possible. The data from each wind tunnel were independently analyzed by the respective organization. The results from these tests show good agreement. In both facilities, interference with acoustic measurement is evident at angles in the forward quadrant.

Ovarian transcriptome associated with reproductive senescence in the long-living Ames dwarf mice.

Science.gov (United States)

Schneider, Augusto; Matkovich, Scot J; Saccon, Tatiana; Victoria, Berta; Spinel, Lina; Lavasani, Mitra; Bartke, Andrzej; Golusinski, Pawel; Masternak, Michal M

2017-01-05

The aim of the current work was to evaluate the ovarian follicle reserve and the ovarian transcriptome in Ames dwarf (df/df) mice. The results suggest a delayed ovarian aging in df/df mice compared to normal (N) mice. Although a high number of genes were differentially expressed during aging of N mice, only a small fraction of these changed with aging in df/df mice. These alterations involved more than 500 categorized biological processes. The majority of these biological processes, including inflammatory/immune responses, were up-regulated with aging in N mice, while old df/df mice were characterized by down-regulation of these same processes in comparison to age matched N mice. However, biological processes related to DNA damage and repairing were commonly down-regulated with aging in both genotypes. In conclusion, delayed ovarian aging in long-living df/df mice was associated with reduced expression of genes related to the inflammatory and immune responses. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Construction of a 2- by 2-foot transonic adaptive-wall test section at the NASA Ames Research Center

Science.gov (United States)

Morgan, Daniel G.; Lee, George

1986-01-01

The development of a new production-size, two-dimensional, adaptive-wall test section with ventilated walls at the NASA Ames Research Center is described. The new facility incorporates rapid closed-loop operation, computer/sensor integration, and on-line interference assessment and wall corrections. Air flow through the test section is controlled by a series of plenum compartments and three-way slide vales. A fast-scan laser velocimeter was built to measure velocity boundary conditions for the interference assessment scheme. A 15.2-cm- (6.0-in.-) chord NACA 0012 airfoil model will be used in the first experiments during calibration of the facility.

NATO Allied Medical Publication 7.5 (AMedP 7.5) NATO Planning Guide for the Estimation of CBRN Casualties

Science.gov (United States)

2016-12-01

PROMULGATION [ Date ] 1. The enclosed Allied Medical Publication AMedP-7.5, NATO Planning Guide for the Estimation of CBRN Casualties, which has been... radioisotopes modeled are 60Co, 90Sr, 99Mo, 125I, 131I, 137Cs, 192Ir, 226Ra, 238Pu, 241Am, 252Cf. 2) Whole-body irradiation (from cloudshine, groundshine,9... Earth Shelter 16.67 66.67 Exposed/Dismounted 1.00 1.00 Foxhole (nuclear only)† 3.00 10.00 Masonry Building 8.33 6.67 Multi-Story Brick Building 1.33

The Intermediate Velocity Source in the 40Ca + 197Au Reaction at 35 AMeV

International Nuclear Information System (INIS)

Planeta, R.; Sosin, Z.; Hachaj, P.

2001-01-01

The creation of hot Ca-like fragments and the emission of intermediate velocity particles was studied in the 40 Ca+ 197 Au reaction at 35 AMeV. For peripheral collisions the primary projectile-like fragment was reconstructed using the AMPHORA 4π detector system. The particle distributions are compared with the predictions of a Monte Carlo code which calculates the nucleon transfer and clustering probabilities according to the system density of states. The velocity distributions of charged particles projected on the beam direction can be explained if emissions from the hot projectile-like fragment and the target-like fragment are supplemented by an emission from an intermediate velocity source located between them. The properties of the intermediate velocity source are properly described, including the 2 D/ 3 T/ 3 He effect. (author)

Thermo Physics Facilities Branch Brochure ARC Jet Complex Fact Sheets, Hypervelocity Free-Flight Aerodynamic Facility Fact Sheets, Ames Vertical Gun Range Fact Sheets

Science.gov (United States)

Fretter, E. F. (Editor); Kuhns, Jay (Editor); Nuez, Jay (Editor)

2003-01-01

The Ames Arc Jet Complex has a rich heritage of over 40 years in Thermal Protection System (TPS) development for every NASA Space Transportation and Planetary program, including Apollo, Space Shuttle, Viking, Pioneer-Venus, Galileo, Mars Pathfinder,Stardust, NASP,X-33,X-34,SHARP-B1 and B2,X-37 and Mars Exploration Rovers. With this early TPS history came a long heritage in the development of the arc jet facilities. These are used to simulate the aerodynamic heating that occurs on the nose cap, wing leading edges and on other areas of the spacecraft requiring thermal protection. TPS samples have been run in the arc jets from a few minutes to over an hour,from one exposure to multiple exposures of the same sample, in order t o understand the TPS materials response to a hot gas flow environment (representative of real hyperthermal environments experienced in flight). The Ames Arc l e t Complex is a key enabler for customers involved in the three major areas of TPS development: selection, validation, and qualification. The arc jet data are critical for validating TPS thermal models, heat shield designs and repairs, and ultimately for flight qualification.

Elastic and inelastic scattering of 9,11 Li + Si at backward angles in the energy range (9.5 - 25) AMeV

International Nuclear Information System (INIS)

Petrascu, M.; Bordeanu, C.; Isbasescu, A.; Mihai, I.; Giurgiu, M.

1997-01-01

Recently, an inclusive fusion experiment of 9,11 Li projectiles with Si targets, in the energy range (9.5 - 25) AMeV has been performed at Riken Ring Cyclotron-Japan using, for the detection of the fusion products, an ionization chamber, MUSIC, built in NIPNE-HH, Bucharest. In this experiment, the contribution of elastic and inelastic scattering, at forward detection angles is eliminated through the experimental set-up. For a clear investigation of the fusion process, the estimation of elastic and inelastic scattering at backward angles, between 80 angle - 180 angle was considered necessary. This estimation was made by the coupled channels computer code ECIS. ECIS is an iterative method, the first iteration of this procedure being DWBA. In the analysis of elastic and inelastic scattering of 9,11 Li projectile on Si target we assumed that the incident 9 Li and 11 Li waves are diffracted by an optical potential with an Woods-Saxon geometry. The adopted optical potential is given. For the depth of the real and imaginary volume terms we used values dependent on projectile energy and target mass number. These values have been chosen in good agreement with a semi-microscopic model with a double-folding potential. The set of optical parameters selected for the system 9,11 Li (13 AMeV) + Si is given. The presence of neutron halo of 11 Li nucleus was taken into account by using adjusted values for the parameters r R and a R . The 28 Si nucleus is considered a rigid rotor, including the couplings involving the ground state and a first to excited states. The quadrupole deformation parameter was β 2 = - 0.24. The results for the scattering of 11 Li projectile on Si target at 13 AMeV energy are given with the parameters R match , I and J max taken from the Monte Carlo simulations with PACE code. We found that the contribution of elastic and inelastic scattering for background angles, between 80 angle - 180 angle is under 2%. The contribution of a inelastic scattering taken

Ames Optimized TCA Configuration

Science.gov (United States)

Cliff, Susan E.; Reuther, James J.; Hicks, Raymond M.

1999-01-01

Configuration design at Ames was carried out with the SYN87-SB (single block) Euler code using a 193 x 49 x 65 C-H grid. The Euler solver is coupled to the constrained (NPSOL) and the unconstrained (QNMDIF) optimization packages. Since the single block grid is able to model only wing-body configurations, the nacelle/diverter effects were included in the optimization process by SYN87's option to superimpose the nacelle/diverter interference pressures on the wing. These interference pressures were calculated using the AIRPLANE code. AIRPLANE is an Euler solver that uses a unstructured tetrahedral mesh and is capable of computations about arbitrary complete configurations. In addition, the buoyancy effects of the nacelle/diverters were also included in the design process by imposing the pressure field obtained during the design process onto the triangulated surfaces of the nacelle/diverter mesh generated by AIRPLANE. The interference pressures and nacelle buoyancy effects are added to the final forces after each flow field calculation. Full details of the (recently enhanced) ghost nacelle capability are given in a related talk. The pseudo nacelle corrections were greatly improved during this design cycle. During the Ref H and Cycle 1 design activities, the nacelles were only translated and pitched. In the cycle 2 design effort the nacelles can translate vertically, and pitch to accommodate the changes in the lower surface geometry. The diverter heights (between their leading and trailing edges) were modified during design as the shape of the lower wing changed, with the drag of the diverter changing accordingly. Both adjoint and finite difference gradients were used during optimization. The adjoint-based gradients were found to give good direction in the design space for configurations near the starting point, but as the design approached a minimum, the finite difference gradients were found to be more accurate. Use of finite difference gradients was limited by the

Radiation-induced mutagenicity and lethality in Ames tester strains of Salmonella

International Nuclear Information System (INIS)

Isildar, M.; Bakale, G.

1984-01-01

Mutation and killing induced by X radiation and 60 Co γ radiation were studied in six different histidine-requiring auxotrophs of Salmonella typhimurium. Strain TA100, which is sensitive to base-pair substitutions, and strains TA2637 and TA98, which are sensitive to frameshifts, carry the pKM101 plasmid and exhibit significantly higher radiation-induced mutations compared to their plasmidless parent strains TA1535, TA1537, and TA1538, respectively. Among the plasmid-containing strains, TA98 and TA2637 are much more sensitive to the mutagenic action of radiation than is TA100 based on a comparison with their respective spontaneous mutation rates; however, no uniformity was observed in the responses of the strains to the lethal action of ionizing radiation. The following conclusions are consistent with these observations: (1) the standard Ames Salmonella assay correctly identifies ionizing radiation as a mutagenic agent; (2) frameshift-sensitive parent strains are more sensitive to the mutagenic effects of ionizing radiation than is the only strain studied that is sensitive to base-pair substitutions; and (3) enhancement of mutagenesis and survival is related to plasmid-mediated repair of DNA damage induced by ionizing radiation and does not involve damage induced by Cerenkov-generated uv radiation which is negligible for our irradiation conditions

Kerry panustab jõule ja tarkusele / Neeme Raud

Index Scriptorium Estoniae

Raud, Neeme, 1969-

2004-01-01

Autor teeb ülevaate lõppevast USA demokraatide valimiseelsest kongressist, mille peateemaks oli presidendikandidaadi John Kerry laiemale avalikkusele tutvustamine. Lisa: Demokraatide kandidaat John Kerry

Plans for Testing the NREL Unsteady Aerodynamics Experiment 10m Diameter HAWT in the NASA Ames Wind Tunnel: Minutes, Conclusions, and Revised Text Matrix from the 1st Science Panel Meeting

Energy Technology Data Exchange (ETDEWEB)

Simms, D.; Schreck, S.; Hand, M.; Fingersh, L.; Cotrell, J.; Pierce, K.; Robinson, M.

2000-08-28

Currently, the NREL Unsteady Aerodynamics Experiment (UAE) research turbine is scheduled to enter the NASA Ames 80-ft x 120-ft wind tunnel in early 2000. To prepare for this 3-week test, a Science Panel meeting was convened at the National Wind Technology Center (NWTC) in October 1998. During this meeting, the Science Panel and representatives from the wind energy community provided numerous detailed recommendations regarding test activities and priorities. The Unsteady Aerodynamics team of the NWTC condensed this guidance and drafted a detailed test plan. This test plan represents an attempt to balance diverse recommendations received from the Science Panel meeting, while taking into account multiple constraints imposed by the UAE research turbine, the NASA Ames 80-ft x 120-ft wind tunnel, and other sources. The NREL-NASA Ames wind tunnel tests will primarily be focused on obtaining rotating blade pressure data. NREL has been making these types of measurements since 1987 and has considerable experience in doing so. The purpose of this wind tunnel test is to acquire accurate quantitative aerodynamic and structural measurements, on a wind turbine that is geometrically and dynamically representative of full-scale machines, in an environment free from pronounced inflow anomalies. These data will be exploited to develop and validate enhanced engineering models for designing and analyzing advanced wind energy machines.

The NASA Ames Hypersonic Combustor-Model Inlet CFD Simulations and Experimental Comparisons

Science.gov (United States)

Venkatapathy, E.; Tokarcik-Polsky, S.; Deiwert, G. S.; Edwards, Thomas A. (Technical Monitor)

1995-01-01

Computations have been performed on a three-dimensional inlet associated with the NASA Ames combustor model for the hypersonic propulsion experiment in the 16-inch shock tunnel. The 3-dimensional inlet was designed to have the combustor inlet flow nearly two-dimensional and of sufficient mass flow necessary for combustion. The 16-inch shock tunnel experiment is a short duration test with test time of the order of milliseconds. The flow through the inlet is in chemical non-equilibrium. Two test entries have been completed and limited experimental results for the inlet region of the combustor-model are available. A number of CFD simulations, with various levels of simplifications such as 2-D simulations, 3-D simulations with and without chemical reactions, simulations with and without turbulent conditions, etc., have been performed. These simulations have helped determine the model inlet flow characteristics and the important factors that affect the combustor inlet flow and the sensitivity of the flow field to these simplifications. In the proposed paper, CFD modeling of the hypersonic inlet, results from the simulations and comparison with available experimental results will be presented.

Emission Spectroscopy and Radiometric Measurements in the NASA Ames IHF Arc Jet Facility

Science.gov (United States)

Winter, Michael W.; Raiche, George A.; Prabhu, Dinesh K.

2012-01-01

Plasma diagnostic measurement campaigns in the NASA Ames Interaction Heating Facility (IHF) have been conducted over the last several years with a view towards characterizing the flow in the arc jet facility by providing data necessary for modeling and simulation. Optical emission spectroscopy has been used in the plenum and in the free jet of the nozzle. Radiation incident over a probe surface has also been measured using radiometry. Plenum measurements have shown distinct radial profiles of temperature over a range of operating conditions. For cases where large amounts of cold air are added radially to the main arc-heated stream, the temperature profiles are higher by as much as 1500 K than the profiles assumed in flow simulations. Optical measurements perpendicular to the flow direction in the free jet showed significant contributions to the molecule emission through inverse pre-dissociation, thus allowing determination of atom number densities from molecular emission. This has been preliminarily demonstrated with the N2 1st Positive System. Despite the use of older rate coefficients, the resulting atom densities are reasonable and surprisingly close to flow predictions.

Web aitab nutikamaid firmasid / Peeter Stamberg

Index Scriptorium Estoniae

Stamberg, Peeter

2003-01-01

Interneti-lahendustesse investeerimine on aidanud paljudel ettevõtetel oma tulemusi parandada. Autor teeb ülevaate ajakirjas BusinessWeek avaldatud edukamatest internetiprojektidest. Lisa: Internetiäri teine laine

Ryanair lubab tuua 300 000 turisti ja 300 uut töökohta / Teele Tammeorg, Dannar Leitmaa

Index Scriptorium Estoniae

Tammeorg, Teele

2010-01-01

Odavlennufirma Ryanair teeb esimesed otselennud Tallinnast 13. detsembril, lennuühendus luuakse seitsme Euroopa linnaga. Riiast lendavad Ryanairi lennukid 44 sihtkohta. Keskmine lennupileti hind on 35 eurot

AMES, NESC and ENIQ: European networks in the field of structural integrity involving NDE and inspection effectiveness assessment

International Nuclear Information System (INIS)

Crutzen, S.; Hurst, R.; Debarberis, L.; Lemaitre, P.; Eriksen, B.

1999-01-01

Three European networks on structural integrity aspects of ageing nuclear components are presently managed by the Institute for Advanced Materials of the Joint Research Centre of the European Commission: AMES (Ageing Materials Evaluation and Studies), ENIQ (European Network for Inspection Qualification) and NESC (Network for Evaluating Steel Components). All three networks involve actions, which aim at the effectiveness and reliability assessment of NDE techniques and of inspection procedures: Either for materials damage detection and characterisation or for defect detection and evaluation. This paper is describing very generally the objectives of the three networks and is then concentrating on the results obtained in ENIQ, which are relevant with ISI and regulatory issues. (orig./DGE)

A New Way of Doing Business: Reusable Launch Vehicle Advanced Thermal Protection Systems Technology Development: NASA Ames and Rockwell International Partnership

Science.gov (United States)

Carroll, Carol W.; Fleming, Mary; Hogenson, Pete; Green, Michael J.; Rasky, Daniel J. (Technical Monitor)

1995-01-01

NASA Ames Research Center and Rockwell International are partners in a Cooperative Agreement (CA) for the development of Thermal Protection Systems (TPS) for the Reusable Launch Vehicle (RLV) Technology Program. This Cooperative Agreement is a 30 month effort focused on transferring NASA innovations to Rockwell and working as partners to advance the state-of-the-art in several TPS areas. The use of a Cooperative Agreement is a new way of doing business for NASA and Industry which eliminates the traditional customer/contractor relationship and replaces it with a NASA/Industry partnership.

Housing differences in the late soviet city : the case of Tartu, Estonia / Hill Kulu

Index Scriptorium Estoniae

Kulu, Hill

2003-01-01

Autor teeb 1989. aasta rahvaloenduse andmetele tuginedes ülevaate Tartu elanikkonna eluasemete omandivormidest, elamistingimuste erinevustest ning seda mõjutavatest teguritest nõukogude perioodi lõpul. Diagrammid ja tabelid

Norma aktsionäridel lootus erakorralisele dividendile / Annika Matson

Index Scriptorium Estoniae

Matson, Annika, 1976-

2004-01-01

Kolmandas kvartalis paremat kasumlikkust näidanud Norma juhtkond teeb aasta alguses nõukogule ettepaneku maksta erakorralisi dividende. Diagramm: Ettevõtetel olev vaba raha aktsia kohta. Kommenteerib Teet Kolts

Börsilt ei tule kunagi lihtsalt raha / Gary Weissi ; interv. Neeme Raud

Index Scriptorium Estoniae

Weissi, Gary

2003-01-01

Intervjuu ajakirja Business Week vanemkorrespondendi ja raamatu "Born To Steal" autori Gary Weissiga aktsiapettustest ja organiseeritud kuritegevuse seostest börsidega. Autor teeb lühikokkuvõtte oma raamatust

Letter from Little Lithuania / Michael Tarm

Index Scriptorium Estoniae

Tarm, Michael

2004-01-01

Autor teeb ülevaate Eesti, Läti, Leedu toodetest ja kaubamärkidest USA turul, Baltimaadesse puutuva kajastamisest USA meedias ning USA avalikkuse teadlikkusest Balti riikidest, sportlastest ja kultuuritegelastest

KGB kunagisest kontorist tehakse noobel korterelamu / Kristjan Pihl

Index Scriptorium Estoniae

Pihl, Kristjan

2011-01-01

Tallinnas Pagari 1 asuva muinsuskaitsealuse juugendstiilis hoone renoveerimisest korterelamuks. Kavandi teeb AB ARS Projekt. Ajaloolase Robert Nermani sõnul lasi William Tulip selle maja 1912. a. ehitada esialgu kortermajaks

Desarrollo y productividad de ñame (Dioscorea trifida y Dioscorea esculenta en diferentes condiciones hídricas

Directory of Open Access Journals (Sweden)

Alba Nelly Acevedo Mercado

2015-01-01

Full Text Available En la región Montes de María (9° 24' 56,33" N y 75° 23' 04,19" O, departamento de Sucre, Colombia, en zonas de clima cálido (26 °C y 30 °C y de clima medio (20 °C y 24 °C, humedad relativa entre 75 y 85% y precipitación de 750 mm durante el ensayo se estudió el efecto del riego en el desarrollo y productividad de dos especies de ñame en peligro de extinción (Dioscorea trifida y Dioscorea esculenta en un diseño experimental de parcelas subdivididas, donde las variables fueron tres condiciones hídricas: riego de 888 mm durante la etapa crítica del cultivo, riego de 944 mm durante todo el ciclo del cultivo, y ausencia de riego con una oferta de agua de 750 mm provenientes de precipitación. La densidad de siembra fue de 10,000 plantas/ha, labranza tradicional con arado de discos y cosecha 8 meses después de la siembra. Como variables se midieron rendimiento de ñame, contenido de almidón, longitud y diámetro de tubérculos y biomasa aérea. Dioscorea trifida presentó un rendimiento promedio de 30.6 t/ha y D. esculenta de 27 t/ha, con contenidos de almidón de 21.3 y 21.6% en base húmeda, respectivamente; la longitud promedio de tubérculos para D. trifida fue de 17.4 cm y para D. esculenta de 11.4 cm; los diámetros promedio fueron 14.4 cm y 10.5 cm y la biomasa aérea 1.1 kg/planta y 0.67 kg/planta, respectivamente. La aplicación de riego al cultivo produjo un incremento en la producción con respecto al cultivo sin riego, para Dioscorea trifida este incremento fue de 78.9% y para Dioscorea esculenta de 92.9%.

Adjoint Method and Predictive Control for 1-D Flow in NASA Ames 11-Foot Transonic Wind Tunnel

Science.gov (United States)

Nguyen, Nhan; Ardema, Mark

2006-01-01

This paper describes a modeling method and a new optimal control approach to investigate a Mach number control problem for the NASA Ames 11-Foot Transonic Wind Tunnel. The flow in the wind tunnel is modeled by the 1-D unsteady Euler equations whose boundary conditions prescribe a controlling action by a compressor. The boundary control inputs to the compressor are in turn controlled by a drive motor system and an inlet guide vane system whose dynamics are modeled by ordinary differential equations. The resulting Euler equations are thus coupled to the ordinary differential equations via the boundary conditions. Optimality conditions are established by an adjoint method and are used to develop a model predictive linear-quadratic optimal control for regulating the Mach number due to a test model disturbance during a continuous pitch

Kamina valik : disain ja funktsionaalsus

Index Scriptorium Estoniae

2007-01-01

Kaminasalongi Tulering juht Hanno Tammvere salongis pakutavatest Belgia firmas Stuv ja Poola firmas Hadjuk kaminatest. Salong teeb koostööd eesti sisearhitektidega (14 nime), tellida saab kamina projekteerimisest paigaldamiseni

Ago Silde : "Olin täiesti ebatüüpiline maavanem" / Ago Silde ; interv. Erik Gamzejev

Index Scriptorium Estoniae

Silde, Ago

2007-01-01

Ilmunud ka: Severnoje Poberezhje : Subbota, 12. mai 2007, lk. 3. Intervjueeritav teeb tagasivaate oma tööle Ida-Viru maavanemana, ka parlamendivalimistest. Arvamust avaldavad Tõnis Seesmaa ja Urve Erikson

S pritselom na Belõi dom

Index Scriptorium Estoniae

2006-01-01

USA vahevalimised andsid stardi presidendikandidaatide ülesseadmise kampaaniaks. Hillary Clinton kogus valimistel oma osariigis 70% häältest, mis teeb temast demokraatide kandidaatide hulgas liidri. Vabariiklaste kandidaadid presidendi kohale

Jätkub filmisari "Ainult friikidele"

Index Scriptorium Estoniae

2008-01-01

Filmisarjas "Ainult friikidele" linastub Tallinnas Sõpruse kinos täna ja Tartus Athena Keskuses homme Alain Corneau' kutuslik kriminaalfilm "Serie noir" : Prantsusmaa 1979. Suurepärase rolli teeb Patrick Dewaere

Dokumentaalsari okupatsioonist

Index Scriptorium Estoniae

2000-01-01

Videofilm "Esimene punane aasta" Eesti ajaloost 1939-40 : Autorid Karl Kello ja Arvo Vilu : Kistler- Ritso Eesti Sihtasutus 2000. Sihtasutus teeb filme loodavale okupatsiooni muuseumile. Sihtasutuse patrooniks on president Lennart Meri

Moeteateid Pariisist / Urmas Väljaots

Index Scriptorium Estoniae

Väljaots, Urmas, 1981-

2008-01-01

Pariisi moemaja Chloe. Belgia moekunstnik Maison Martin Margiela. Parfüümireklaamides kasutatakse kuulsaid filminäitlejaid. Kiirmoekett H & M teeb koostööd kuulsate disaineritega. Pariisi tänavamood

Assa Evolution - lukustuse uus põlvkond / Maigi Peeduli

Index Scriptorium Estoniae

Peeduli, Maigi

2003-01-01

Rootsi lukufirma Assa AB tootearendus põhineb moodulsüsteemil, mis teeb elu mugavaks arhitektidel, ehitajatel ja lukukasutajatel, kuna see võimaldab lukuraame komplekteerida erinevate südamike, linkide ja katetega

Assa Evolution - novoje pokolenije zamkov / Maigi Peeduli

Index Scriptorium Estoniae

Peeduli, Maigi

2003-01-01

Rootsi lukufirma Assa AB tootearendus põhineb moodulsüsteemil, mis teeb elu mugavaks arhitektidel, ehitajatel ja lukukasutajatel, kuna see võimaldab lukuraame komplekteerida erinevate südamike, linkide ja katetega

Tippdisain Hank Vu'lt Urbana teostuses

Index Scriptorium Estoniae

1999-01-01

Vietnamis sündinud, Ameerika Ühendriikides Kalifornias töötav arhitektiharidusega mööblidisainer Hank Vu teeb lihtsat, funktsionaalset, abstraktselt orgaanilise vormiga mööblit. 6 illustratsiooni

Mis meil Aasiast? / Marianne Mikko

Index Scriptorium Estoniae

Mikko, Marianne, 1961-

2008-01-01

Ilmunud ka: Severnoje Poberezhje 6. august lk. 2, Põhjarannik, Koit 7. august lk. 2,6. Europarlamendiliige teeb ülevaate oma visiidist Hiinasse ja Kambodzhasse, eesmärgiga koguda infot Tiibetis toimuvast

Transforming BIM to BEM: Generation of Building Geometry for the NASA Ames Sustainability Base BIM

Energy Technology Data Exchange (ETDEWEB)

O' Donnell, James T. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Maile, Tobias [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Rose, Cody [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Mrazovic, Natasa [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Morrissey, Elmer [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Regnier, Cynthia [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Parrish, Kristen [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Bazjanac, Vladimir [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

2013-01-01

Typical processes of whole Building Energy simulation Model (BEM) generation are subjective, labor intensive, time intensive and error prone. Essentially, these typical processes reproduce already existing data, i.e. building models already created by the architect. Accordingly, Lawrence Berkeley National Laboratory (LBNL) developed a semi-automated process that enables reproducible conversions of Building Information Model (BIM) representations of building geometry into a format required by building energy modeling (BEM) tools. This is a generic process that may be applied to all building energy modeling tools but to date has only been used for EnergyPlus. This report describes and demonstrates each stage in the semi-automated process for building geometry using the recently constructed NASA Ames Sustainability Base throughout. This example uses ArchiCAD (Graphisoft, 2012) as the originating CAD tool and EnergyPlus as the concluding whole building energy simulation tool. It is important to note that the process is also applicable for professionals that use other CAD tools such as Revit (“Revit Architecture,” 2012) and DProfiler (Beck Technology, 2012) and can be extended to provide geometry definitions for BEM tools other than EnergyPlus. Geometry Simplification Tool (GST) was used during the NASA Ames project and was the enabling software that facilitated semi-automated data transformations. GST has now been superseded by Space Boundary Tool (SBT-1) and will be referred to as SBT-1 throughout this report. The benefits of this semi-automated process are fourfold: 1) reduce the amount of time and cost required to develop a whole building energy simulation model, 2) enable rapid generation of design alternatives, 3) improve the accuracy of BEMs and 4) result in significantly better performing buildings with significantly lower energy consumption than those created using the traditional design process, especially if the simulation model was used as a predictive

3rd Annual NASA Ames Space Science and Astrobiology Jamboree

Science.gov (United States)

Dotson, Jessie

2015-01-01

The Space Science and Astrobiology Division at NASA Ames Research Center consists of over 50 civil servants and more than 110 contractors, co-­-ops, post-­-docs and associates. Researchers in the division are pursuing investigations in a variety of fields including exoplanets, planetary science, astrobiology and astrophysics. In addition, division personnel support a wide variety of NASA missions including (but not limited to) Kepler, SOFIA, LADEE, JWST, and New Horizons. With such a wide variety of interesting research going on, distributed among three branches in at least 5 different buildings, it can be difficult to stay abreast of what one's fellow researchers are doing. Our goal in organizing this symposium is to facilitate communication and collaboration among the scientists within the division, and to give center management and other ARC researchers and engineers an opportunity to see what scientific research and science mission work is being done in the division. We are also continuing the tradition within the Space Science and Astrobiology Division to honor one senior and one early career scientist with the Pollack Lecture and the Early Career Lecture, respectively. With the Pollack Lecture, our intent is to select a senior researcher who has made significant contributions to any area of research within the space sciences, and we are pleased to honor Dr. William Borucki this year. With the Early Career Lecture, our intent is to select a young researcher within the division who, by their published scientific papers, shows great promise for the future in any area of space science research, and we are pleased to honor Dr. Melinda Kahre this year

Metalingvistiline teadlikkus võõrkeeleõppes : oma keel võõras peeglis / Annekatrin Kaivapalu

Index Scriptorium Estoniae

Kaivapalu, Annekatrin, 1963-

2010-01-01

Uuritakse, milliseid tähelepanekuid teeb õppija võõrkeeli õppides oma emakeele, antud juhul eesti ja soome keele kohta ning kas ja millises osas ühtivad õppijate arusaamad keelte lingvistiliste kirjeldustega

Res Publica asus Reformierakonda Tallinna võimuliidust tõrjuma / Mirko Ojakivi

Index Scriptorium Estoniae

Ojakivi, Mirko

2005-01-01

Res Publica Tallinna piirkonna juhatuse liikme Siim Roode sõnul teeb Res Publica Keskerakonna Tallinna piirkonna juhatusele ettepaneku koalitsiooniläbirääkimiste alustamiseks. Lisa: Paltsu ettekäändeks Unicom

Maksuvõlglaste arv kahanes aastaga protsendi võrra

Index Scriptorium Estoniae

2004-01-01

Maksu- ja tolliameti maksuvõlgade sissenõudmise osakonna juht Raul Siem teeb ülevaate eraisikutest maksumaksjate ja ettevõtete maksuvõlgadest 2004. aastal ning selgitab maksuvõlgade ennetamise ja sissenõudmise protseduuri

Huellas de las religiones tradicionales del África subsahariana en América Latina y el Caribe

Directory of Open Access Journals (Sweden)

Lazaro Cabrera Thompson

2008-01-01

Full Text Available El artículo explora las religiones tradicionales practicadas por los pueblos ewe-mina, ewe-fon, bantú y yoruba del África subsahariana, antes de abordar las formas como estas prácticas religiosas persisten en el “Nuevo Mundo” tras la llegada forzosa de aquellos esclavizados africanos. Con base en la presencia de estas religiones tradicionales africanas en distintos países latinoamericanos y caribeño, se evidencia un conjunto religioso fusionado por historias, mitos, leyendas, danza, música, etc. de ascendencia africana y se hace un llamado a los/ as investigadores/as, que desde América Latina y el Caribe, indagan sobre las religiones tradicionales yoruba, para que franqueen los límites de Nigeria con el fin de abarcar a toda la diáspora yoruba.

Borisov not packing his bags yet

Index Scriptorium Estoniae

2004-01-01

Leedu kodakondsusest ilma jäetud ärimees Juri Borissov esitas migratsiooniametile taotluse Leedus alalise elamisloa saamiseks. Migratsiooniamet teeb lähipäevil otsuse Borissovi Leetu jäämise lubamise osas

Riigikogu restart / Urmas Reinsalu

Index Scriptorium Estoniae

Reinsalu, Urmas, 1975-

2007-01-01

Riigikogus on seaduste massilise menetlemise periood lõppenud, kirjutab autor ja teeb ettepanekuid parlamendi teise etapi tööks, soovides rohkem järelevalvet, rohkem paindlikkust debattide korraldamisel, rohkem initsiatiive valdkonnapoliitikate asjus

BBC filmib Eesti elu pärast võitu Eurovisioonil / Aarne Mäe

Index Scriptorium Estoniae

Mäe, Aarne, 1967-

2002-01-01

BBC teeb dokumentaalfilmi ning salvestas Rakvere Teatri kohvikus Eurovisiooni lauluvõistluse võitnud Tanel Padarit ja tema ansamblit Speed Free. Filmi režissöör on Marina Zenovich, produtsent Celia Quartiermain

Russalka laevahukk jõuab maailma telepilti / Riho Laurisaar

Index Scriptorium Estoniae

Laurisaar, Riho

2005-01-01

Kanada filmigrupp Eco-Nova Productions Ltd teeb Eesti Meremuuseumi ja Tuukritööde OÜ abiga Soome lahes 1893.a. hukkunud vene sõjalaeva Russalka vrakist dokumentaalfilmi National Geographicu ja Discovery Channeli jaoks

Uudised : ERSO menu Rootsis. Õhtu Metropolitan Operas. NYYD Ensemble'i kontserdid / Madis Kolk

Index Scriptorium Estoniae

Kolk, Madis, 1953-

2001-01-01

ERSO kontserdireisist Rootsis. "Klassikaraadio" teeb 17. veebr. otseülekande New Yorgi Metropolitan Operast, kus tuleb ettekandele Rossini ooepr "Itaallanna Alzhiiris". NYYD Ensemble'i kontsertidest Pärnus ja Tallinnas kontserdisarjas "I Got Rhythm"

Mõttetalgud tõid idee anda lastele valimistel hääl / Tõnis Lukas

Index Scriptorium Estoniae

Lukas, Tõnis, 1962-

2009-01-01

Lastega perede osakaalu tõstmine ühiskondlike otsuste mõjutamiseks on kõige loomulikum laste endi kaudu. Seepärast teeb haridusminister Tõnis Lukase ettepaneku anda igale lapsele valimistel hääl

Scholarship, publication, and career advancement in health professions education: AMEE Guide No. 43.

Science.gov (United States)

McGaghie, William C

2009-07-01

Scholarship and publication are key contributors to career advancement in health professions education worldwide. Scholarship is expressed in many ways including original research; integration and synthesis of ideas and data, often across disciplines; application of skill and knowledge to problems that have consequences for health professionals, students, and patients; and teaching in many forms. Professional publication also has diverse outlets ranging from empirical articles in peer reviewed journals, textbook chapters, videos, simulation technologies, and many other means of expression. Scholarship and publication are evaluated and judged using criteria that are consensual, public, and transparent. This three-part AMEE Guide presents advice about how to prepare and publish health professions education research reports and other forms of scholarship in professional journals and other outlets. Part One addresses scholarship-its varieties, assessment, and attributes of productive scholars and scholarly teams. Part Two maps the road to publication, beginning with what's important and reportable and moving to manuscript planning and writing, gauging manuscript quality, manuscript submission and review, and writing in English. Part Three offers 21 practical suggestions about how to advance a successful and satisfying career in the academic health professions. Concluding remarks encourage health professions educators to pursue scholarship with vision and reflection.

Baltoscandal kingib linlastele etenduse / Aarne Mäe

Index Scriptorium Estoniae

Mäe, Aarne, 1967-

2002-01-01

Rahvusvaheline teatrifestival Baltoscandal teeb ühe etendusega kingituse linnarahvale : 14. juunil näidatakse Rakvere Teatris Battery Dance Company programmi "Used Car Salesman", "Mother Goose", "Layapriya", "The anyones ballet", lavastaja ja koreograaf Jonathan Hollander

Democracy in a bottle : attitudes towards alcohol regulation in the Post-Communist Baltic Sea Region / Therese C. Reitan

Index Scriptorium Estoniae

Reitan, Therese C.

2003-01-01

Baltimaades ja Poolas läbi viidud uuringust eesmärgiga selgitada välja avalikkuse suhtumine alkoholi, selle kättesaadavusega seotud probleemide reguleerimise kohta. Autor teeb ülevaate uuringu tulemustest. Tabelid. Lisa

ROK saavutas valemängureid paljastades ajaloolise võidu / Tõnu Kees

Index Scriptorium Estoniae

Kees, Tõnu, 1954-

2002-01-01

Maailma ajakirjandus hindas otsust diskvalifitseerida dopingu kastutamisega vahelejäänud murdmaasuusatajad Johann Mühlegg, Larissa Lazutina ja Olga Danilova Rahvusvahelise Olümpiakomitee võiduks. Vt. ka art. EPO noorem vend teeb ilma

Birma hunta jätkab repressioone / Igor Taro

Index Scriptorium Estoniae

Taro, Igor

2007-01-01

Amnesty International teatas, et Birma diktaatorlikud võimud jätkavad teisitimõtlejate vahistamist, samal ajal teeb ÜRO saadik Ibrahim Gambari huntale poliitilise surve avaldamiseks ringsõitu Kagu-Aasias. Lisa: Rahutu riik Birma

Mutagenicity of Tween 80-solvated mild gasification products in the Ames salmonella microsomal assay system

Energy Technology Data Exchange (ETDEWEB)

1992-01-13

The results of the Tween 80-solvated Ames testing of six mild gasification samples indicate significant mutagenic activity only in the composite materials (MG-119 and MG-120), previously suspected from the DMSO-solvated assays, which had shown some variable but ultimately insignificant mutagenic responses. The activity of these samples from the Tween 80-solvated assays was quite low when compared to either the positive controls or the SRC-II HD coal-liquefaction reference material. The class of mutagenic activity expressed by these samples solvated in Tween 80 was that of an indirect-acting, frameshift mutagen(s) since significant activity was found only on tester strain TA98 in the presence of the metabolic activation fraction (S9). Because DMSO and other solvents have been shown to affect the mutagenic activity of certain pure chemicals, the possibility of solvent/mutagen interactions in complex mixtures such as coal-derived liquids exists. Thus, the testing of the genotoxic activity of undefined, chemically complex compounds may require the use of at least two solvent systems to reduce the possibility of artifactual findings. 10 refs., 4 tabs.

Jõgevamaa Kodukandi Ühendus loob koostöövõrgustikku / Helve Laasik ; kommenteerinud Karina Kaarepere

Index Scriptorium Estoniae

Laasik, Helve, 1958-

2009-01-01

Jõgevamaa Kodukandi Ühenduse projektist "Koostöö teeb tugevaks", mille käigus luuakse koostöövõrgustik ühenduse ja külaseltside ning kohalike omavalitsuste vahel. Vabaühenduste Fondi toetustest

Keskmine pension tõuseb / Heimar Lenk

Index Scriptorium Estoniae

Lenk, Heimar, 1946-

2006-01-01

Ilmunud ka: Vali Uudised 8. nov. lk. 2, Videvik 16. nov. lk. 2, Elva Postipoiss 18. nov. lk. 4. Autor teeb tagasivaate Eesti pensionipoliitikale ning kinnitab, et pensionid tõusevad 2007. aastal 18% võrra

Keera korter päikesesse / Tanel Veenre

Index Scriptorium Estoniae

Veenre, Tanel, 1977-

2009-01-01

Itaalia arhitekti David Fisheri pöörleva pilvelõhkuja projektist. 80-korruseline moodulitest ökoelamu peaks valmina Dubais 2010. a. Iga korrus liigub teistest sõltumatult ja teeb 360-kraadise tiiru ühe tunniga

The effective state / Lars Johannsen

Index Scriptorium Estoniae

Johannsen, Lars

2003-01-01

Autor teeb ülevaate ja annab hinnangu riigivalitsemise efektiivsusele Baltimaades, kirjeldab moodsa bürokraatia arengut, väikestes riikides ebaproportsionaalselt suure administratiivstruktuuri kujunemist, selle võimalikke põhjuseid ning mõju riigivalitsemise efektiivsusele. Tabelid

The influence of the development potential of China's economy on the logistics of the East and the West / Ho Jianmin = Влияние потенциала развития китайской экономики на логистику Востока �

Index Scriptorium Estoniae

Jianmin, Ho

2003-01-01

Ettekanne 3.-4. detsembrini 2003 Tallinnas toimunud rahvusvahelisel konverents-näitusel "Logistics and transport in international trade" teeb ülevaate Hiina majanduslikust arengust, väliskaubanduse olukorrast ning arenguprogrammist logistika ja transpordi valdkonnas.Tabelid

Lapse sünd, abiellumine ja juubel toovad töötajale lisaraha / Kristel Kossar

Index Scriptorium Estoniae

Kossar, Kristel

2005-01-01

Konsultatsioonifirma Fontes 2004. aasta palgauuringu andmetel teeb 75 protsenti ettevõtetest töötajatele tähtpäevade puhul kingitusi, milleks on tavaliselt rahaline preemia, ilu- või tarbeese. Lisa: Ettevõtted kingivad

Saaremaa maaelu ja põllumajandus said mullu ligi 140 miljonit toetust / Ain Lember

Index Scriptorium Estoniae

Lember, Ain

2005-01-01

Saare maakond sai 2004. aastal enam kui 138 miljoni krooni eest maaelu- ja põllumajandustoetusi, mis teeb iga maal elava inimese kohta 6760 krooni. Tabelid: Toetussumma maakonna lõikes; Toetussumma iga maal elava inimese kohta (kroonides)

Laulupeost kaks filmi / Anneli Ammas

Index Scriptorium Estoniae

Ammas, Anneli, 1962-

2004-01-01

Tänavusest laulu- ja tantsupeost on Allfilmilt tellinud filmi Prantsuse-saksa telekanal ARTE. USA jaoks teeb filmi "Laulev revolutsioon" USA kompanii Mountain View Production eesti päritolu režissöör Jim Dusty

Conscription debate in Lithuania : how to approach the issue? / Tomas Jermalavicius

Index Scriptorium Estoniae

Jermalavičius, Tomas, 1977-

2002-01-01

Autor teeb sõjaväekohustuse ajaloolise kujunemise ja lääneriikides levivate trendide taustal ülevaate peamistest argumentidest ning seisukohtadest Leedu ühiskonnas toimuvas debatis sõjaväekohustuse võimaliku kaotamise üle

The importance of ports in the transport chain : challenges and opportunities / Dirk K. Behrendt = Значение портов в логистической цепочке : задачи и возможности / Дирк Берендт

Index Scriptorium Estoniae

Behrendt, Dirk K.

2003-01-01

Ettekanne 3.-4. detsembrini 2003 Tallinnas toimunud rahvusvahelisel konverents-näitusel "Logistics and transport in international trade" teeb ülevaate Euroopa, sh Läänemere sadamate ülesannetest, teenustest, konkurentsivõitlusest ning integreeritusest teiste transpordiliikidega

Educational Projects in Unmanned Aerial Systems at the NASA Ames Research Center

Science.gov (United States)

Dahlgren, Robert P.

2017-01-01

Unmanned aerial systems (UAS), autonomy and robotics technology have been fertile ground for developing a wide variety of interdisciplinary student learning opportunities. In this talk, several projects will be described that leverage small fixed-wing UAS that have been modified to carry science payloads. These aircraft provide a unique hands-on experience for a wide range of students from college juniors to graduate students pursuing degrees in electrical engineering, aeronautical engineering, mechanical engineering, applied mathematics, physics, structural engineering and other majors. By combining rapid prototyping, design reuse and open-source philosophies, a sustainable educational program has been organized structured as full-time internships during the summer, part-time internships during the school year, short details for military cadets, and paid positions. As part of this program, every summer one or more UAS is developed from concept through design, build and test phases using the tools and facilities at the NASA Ames Research Center, ultimately obtaining statements of airworthiness and flight release from the Agency before test flights are performed. In 2016 and 2017 student projects focused on the theme of 3D printed modular airframes that may be optimized for a given mission and payload. Now in its fifth year this program has served over 35 students, and has provided a rich learning experience as they learn to rapidly develop new aircraft concepts in a highly regulated environment, on systems that will support principal investigators at university, NASA, and other US federal agencies.

Aeroacoustic Study of a 26%-Scale Semispan Model of a Boeing 777 Wing in the NASA Ames 40- by 80-Foot Wind Tunnel

Science.gov (United States)

Horne, W. Clifton; Burnside, Nathan J.; Soderman, Paul T.; Jaeger, Stephen M.; Reinero, Bryan R.; James, Kevin D.; Arledge, Thomas K.

2004-01-01

An acoustic and aerodynamic study was made of a 26%-scale unpowered Boeing 777 aircraft semispan model in the NASA Ames 40- by 80-Foot Wind Tunnel for the purpose of identifying and attenuating airframe noise sources. Simulated approach and landing configurations were evaluated at Mach numbers between 0.12 and 0.24. Cruise configurations were evaluated at Mach numbers between 0.24 and 0.33. The research team used two Ames phased-microphone arrays, a large fixed array and a small traversing array, mounted under the wing to locate and compare various noise sources in the wing high-lift system and landing gear. Numerous model modifications and noise alleviation devices were evaluated. Simultaneous with acoustic measurements, aerodynamic forces were recorded to document aircraft conditions and any performance changes caused by the geometric modifications. Numerous airframe noise sources were identified that might be important factors in the approach and landing noise of the full-scale aircraft. Several noise-control devices were applied to each noise source. The devices were chosen to manipulate and control, if possible, the flow around the various tips and through the various gaps of the high-lift system so as to minimize the noise generation. Fences, fairings, tip extensions, cove fillers, vortex generators, hole coverings, and boundary-layer trips were tested. In many cases, the noise-control devices eliminated noise from some sources at specific frequencies. When scaled to full-scale third-octave bands, typical noise reductions ranged from 1 to 10 dB without significant aerodynamic performance loss.

Eesti väikefirma aitab lennukite juhtimissüsteeme luua / Raigo Neudorf

Index Scriptorium Estoniae

Neudorf, Raigo

2009-01-01

Info- ja automaatikasüsteemidega tegelev ettevõte IB Krates OÜ teeb koostööd Euroopa lennukitootjaga Airbus, luues lennukite juhtimissüsteemide uut tarkvara. Eestist osaleb koostööprojektis ka Tallinna Tehnikaülikool

Эстонская фирма помогает Airbus / Райго Неудорф

Index Scriptorium Estoniae

Неудорф, Райго

2009-01-01

Info- ja automaatikasüsteemidega tegelev ettevõte IB Krates OÜ teeb koostööd Euroopa lennukitootjaga Airbus, luues lennukite juhtimissüsteemide uut tarkvara. Eestist osaleb koostööprojektis ka Tallinna Tehnikaülikool

Estonians in cyberspace / Pille Runnel

Index Scriptorium Estoniae

Runnel, Pille, 1974-

2003-01-01

Autor teeb ülevaate 2002. aastal Tartu Ülikooli ajakirjanduse ja kommunikatsiooni osakonnas läbi viidud meedia tarbimise uuringu tulemustest, analüüsib Interneti kasutamise, mittekasutamise ning tekkinud digilõhe võimalikke põhjuseid. Diagrammid

Saksa tudengid mängivad Taevalaval Shakespeare'i / Sven Karja

Index Scriptorium Estoniae

Karja, Sven, 1968-

2000-01-01

Tallinna jõuab EMA Lavakunstikooli kutsel Berliini Kunstiakadeemia esindus. Linnateatris esitatakse oma õppelavastus, W. Shakespeare'i komöödia "Kaheteistkümnes öö ehk Kuidas soovite", lavastaja Dieter Bitterli. Lavastuses teeb kaasa ka Tõnu Lensment

Sõnnikust elektri tootmine on Eesti Energia otsustada / Toivo Tänavsuu

Index Scriptorium Estoniae

Tänavsuu, Toivo

2006-01-01

Seakasvatusfirma Ekseko tahab hakata seasõnnikust elektrit ja soojust tootma, kui Eesti Energia finantseerib projekti. Taani konsultatsioonifirma Energy Consulting Network soovitab rajada koostootmisjaama maksumusega umbes 50-60 miljonit krooni. Lisa: Eesti Energia teeb otsuse lähiajal

Nähtamatud kaitseväelased = Invisible members of the Defence Forces / Mari Kamps ; translated by Lingo OÜ

Index Scriptorium Estoniae

Kamps, Mari

2017-01-01

Leitnant Martin Jürise teeb TTÜs doktoritööd hüperspektraal- ja lähiinfrapunakaamerate komplektiga, eesmärgiks on aidata kaitseväelastel end paremini varjata. Osaliselt ilmunud ajakirjas "Inseneeria" 2016, nr. 8

Standorte der Hoch- und Berufsschulen in Estland - Faktor zur Förderung der Regionalpolitik / Matti Raudjärv

Index Scriptorium Estoniae

Raudjärv, Matti

2004-01-01

Kuigi erineva potentsiaaliga, on kõrgharidus esindatud enamikes Eesti maakondades (puudub vaid Hiiu, Jõgeva ja Põlva maakonnas, Valga teeb koostööd Läti Valka linnaga), kuid kutsehariduse regionaalne aspekt on autori arvates kavandatud tasakaalustamatult. Tabel

Training for life science experiments in space at the NASA Ames Research Center

Science.gov (United States)

Rodrigues, Annette T.; Maese, A. Christopher

1993-01-01

As this country prepares for exploration to other planets, the need to understand the affects of long duration exposure to microgravity is evident. The National Aeronautics and Space Administration (NASA) Ames Research Center's Space Life Sciences Payloads Office is responsible for a number of non-human life sciences payloads on NASA's Space Shuttle's Spacelab. Included in this responsibility is the training of those individuals who will be conducting the experiments during flight, the astronauts. Preparing a crew to conduct such experiments requires training protocols that build on simple tasks. Once a defined degree of performance proficiency is met for each task, these tasks are combined to increase the complexity of the activities. As tasks are combined into in-flight operations, they are subjected to time constraints and the crew enhances their skills through repetition. The science objectives must be completely understood by the crew and are critical to the overall training program. Completion of the in-flight activities is proof of success. Because the crew is exposed to the background of early research and plans for post-flight analyses, they have a vested interest in the flight activities. The salient features of this training approach is that it allows for flexibility in implementation, consideration of individual differences, and a greater ability to retain experiment information. This training approach offers another effective alternative training tool to existing methodologies.

Comparative Evaluation of Biochemical Changes in Tomato (Lycopersicon esculentum Mill.) Infected by Alternaria alternata and Its Toxic Metabolites (TeA, AOH, and AME).

Science.gov (United States)

Meena, Mukesh; Zehra, Andleeb; Dubey, Manish K; Aamir, Mohd; Gupta, Vijai K; Upadhyay, Ram S

2016-01-01

In the present study, we have evaluated the comparative biochemical defense response generated against Alternaria alternata and its purified toxins viz. alternariol (AOH), alternariol monomethyl ether (AME), and tenuazonic acid (TeA). The necrotic lesions developed due to treatment with toxins were almost similar as those produced by the pathogen, indicating the crucial role of these toxins in plant pathogenesis. An oxidative burst reaction characterized by the rapid and transient production of a large amount of reactive oxygen species (ROS) occurs following the pathogen infection/toxin exposure. The maximum concentration of hydrogen peroxide (H 2 O 2 ) produced was reported in the pathogen infected samples (22.2-fold) at 24 h post inoculation followed by TeA (18.2-fold), AOH (15.9-fold), and AME (14.1-fold) in treated tissues. 3,3'- Diaminobenzidine staining predicted the possible sites of H 2 O 2 accumulation while the extent of cell death was measured by Evans blue dye. The extent of lipid peroxidation and malondialdehyde (MDA) content was higher (15.8-fold) at 48 h in the sample of inoculated leaves of the pathogen when compared to control. The cellular damages were observed as increased MDA content and reduced chlorophyll. The activities of antioxidative defense enzymes increased in both the pathogen infected as well as toxin treated samples. Superoxide dismutase (SOD) activity was 5.9-fold higher at 24 h post inoculation in leaves followed by TeA (5.0-fold), AOH (4.1-fold) and AME (2.3-fold) treated leaves than control. Catalase (CAT) activity was found to be increased upto 48 h post inoculation and maximum in the pathogen challenged samples followed by other toxins. The native PAGE results showed the variations in the intensities of isozyme (SOD and CAT) bands in the pathogen infected and toxin treated samples. Ascorbate peroxidase (APx) and glutathione reductase (GR) activities followed the similar trend to scavenge the excess H 2 O 2 . The reduction in CAT

Value-based marketing : improving the effectiveness of marketing through integrated marketing management by creating value for customers and shareholders / Toomas Danneberg

Index Scriptorium Estoniae

Danneberg, Toomas, 1970-

2003-01-01

Kaanel ajak. ilmumisaeg 2002/2003. Turukeskse ja väärtusepõhise marketingi erinevustest. Autor teeb ülevaate ettevõtte marketingi juhtimisest ning marketingistrateegia mõjust väärtuste loomisele aktsionäride ja klientide jaoks. Skeemid

Fremantle Media ekspordib seriaale kogu maailma / Andrew Edgecliffe-Johnson ; tõlk. Erik Aru

Index Scriptorium Estoniae

Edgecliffe-Johnson, Andrew

2007-01-01

Teleproduktsioonifirmast Fremantle Media. Saateformaatide eksportimisel saavutatud edu teeb firmast õpikunäite, kuidas viia tooteid üle maailma, muutes neid just piisavalt, et sobida kohaliku maitsega, jäädes samas truuks algideele. Edu ei vaja tõlget

Inglased peavad "South Parki" liiga karmiks

Index Scriptorium Estoniae

2000-01-01

Inglise kooliõpetajaid teeb murelikuks ropp dialoog animafilmis "South Park : suurem, pikem ja lõikamata" ("South Park . Bigger, Longer & Uncut") : Stsenaristid Trey Parker ja Matt Stone : režissöör Trey Parker : Ameerika Ühendriigid 1999

Soome kaudu Hiinasse / Jaan Ruus

Index Scriptorium Estoniae

Ruus, Jaan, 1938-2017

2005-01-01

Soome ja Hiina mütoloogiat ühendava fantaasiafilmi "Armuvalus sõdalane" (eelarve 39 milj. krooni) tootjad on Soome, Holland, Hiina ja Eesti (3,9 milj. krooni). Kaasa teeb ka Elle Kull, lavastab debütant AJ Annila

Soome-Hollandi-Hiina-Eesti ühisfilmi "Armuvalus sõdalane" ("Jade Warrior", rezh Antti-Juhani Annila) filmivõtted algavad 2.VIII Soomes

Index Scriptorium Estoniae

2005-01-01

Soome ja Hiina mütoloogiat ühendava fantaasiafilmi "Armuvalus sõdalane" (eelarve 39 milj. krooni) tootjad on Soome, Holland, Hiina ja Eesti (3,9 milj. krooni). Kaasa teeb ka Elle Kull, lavastab debütant AJ Annila

Vozmozhen li amerikanskii variant na narvskoi potshve? / Tatjana Gritsenko

Index Scriptorium Estoniae

Gritsenko, Tatjana

2007-01-01

Narva linnavalitsuse delegatsioon külastas programmi International Visitor Leadership Program raames USA-d. Visiidi eesmärgiks oli tutvuda kohalike omavalitsuste tööga. Ülevaate külaskäigust teeb Narva abilinnapea Sofja Homjakova

Dave Storm esitleb singlit

Index Scriptorium Estoniae

2002-01-01

7. märtsil klubis Spirit ja 8. märtsil klubis Terminal presenteerib tallinlane DJ Dave Storm oma uut singlit "Ride", millel teeb laulmisega kaasa ameeriklane Charlie C. Singelplaadi annab peadselt välja Inglise plaadifirma Refunkt

Täna kell 19.30 avatakse reisisadama endises politseimajas...

Index Scriptorium Estoniae

2005-01-01

Ranna-ala arenguvõimalusi tutvustav näitus "Tagasi mere juurde. Mereõhk teeb vabaks", linnadevahelise projekti "Grands Travaux" osa. Väljapaneku on koostanud Tallinna linnavalitsusse ja AS Tallinna Sadam tellimusel disainibüroo ZiZi & YoYo

The aftermath of the Soviet occupation in Estonia / Liisi Bucht

Index Scriptorium Estoniae

Bucht, Liisi

2000-01-01

Autor teeb kokkuvõtte Teise maailmasõja ja Nõukogude okupatsiooni järelmõjudest: ühiskonnas toimusid demograafilised muutused, Eesti majanduslik areng seiskus, intelligents ja ettevõtlikum osa rahvast hävitati või pages välismaale

Meie staarid raadioteatris

Index Scriptorium Estoniae

2005-01-01

Raivo Küti raadioetenduses "Papa" teeb oma esimese kuuldemängu rolli Ülle Lichtfeldt. August Gailiti novelli "Seeba kuninganna" järgi loodavas kuuldemängus "Toomas Nipernaadi talv" saab kuulda peaosas Üllar Saaremäed

Ames expedited site characterization demonstration at the former manufactured gas plant site, Marshalltown, Iowa

International Nuclear Information System (INIS)

Bevolo, A.J.; Kjartanson, B.H.; Wonder, J.D.

1996-03-01

The goal of the Ames Expedited Site Characterization (ESC) project is to evaluate and promote both innovative technologies (IT) and state-of-the-practice technologies (SOPT) for site characterization and monitoring. In April and May 1994, the ESC project conducted site characterization, technology comparison, and stakeholder demonstration activities at a former manufactured gas plant (FMGP) owned by Iowa Electric Services (IES) Utilities, Inc., in Marshalltown, Iowa. Three areas of technology were fielded at the Marshalltown FMGP site: geophysical, analytical and data integration. The geophysical technologies are designed to assess the subsurface geological conditions so that the location, fate and transport of the target contaminants may be assessed and forecasted. The analytical technologies/methods are designed to detect and quantify the target contaminants. The data integration technology area consists of hardware and software systems designed to integrate all the site information compiled and collected into a conceptual site model on a daily basis at the site; this conceptual model then becomes the decision-support tool. Simultaneous fielding of different methods within each of the three areas of technology provided data for direct comparison of the technologies fielded, both SOPT and IT. This document reports the results of the site characterization, technology comparison, and ESC demonstration activities associated with the Marshalltown FMGP site. 124 figs., 27 tabs

salmepaat.blogspot.com vahendab muistsete saladuste paljastamist / Andres Sepp

Index Scriptorium Estoniae

Sepp, Andres

2008-01-01

Saaremaalt Salmelt leitud muinaspaadi uurimistööde tulemuste avalikustamiseks lõid arheoloogid Eestis spetsiaalse blogi. Konservaator Aive Rumm Tallinna Ülikooli Ajaloo Instituudist teeb blogis kokkuvõtte Salme muinaslaevast pärit metallesemete seisukorrast ning nende konserveerimise viisidest

Kunstnik kavatseb maalidest jaanitule teha / Erika Prave

Index Scriptorium Estoniae

Prave, Erika, 1970-

2005-01-01

Andrus Older teeb jaanitule oma piltidest, mis jäävad ostmata oksjonil, mille ta korraldab päev enne Sillamäe lähedal Orava talus. Harrastuskunstnik paneb müüki umbes 50 maali. Kunstniku kommentaarid

Siim Nestor soovitab : Zahir / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2007-01-01

Ansambli Zahir debüütalbumi "Green Means Go" esitluskontserdist 8. märtsil Tallinnas Von Krahlis (kaasa teeb ans. Andur). Ameerika diskor ja produtsent DJ Karizma 9. veebr. Tallinna klubis Privé üritusel "Defected in the House"

Võitlus Baltikumi pärast - 15 aastat hiljem / Dag Sebastian Ahlander ; interv. Allan Alaküla

Index Scriptorium Estoniae

Ahlander, Dag Sebastian

2006-01-01

Endine Rootsi peakonsul Leningradis Dag Sebastian Ahlander teeb tagasivaate 1991. aasta sündmustele ning annab omapoolse hinnangu tänapäeva Baltimaadele. Praegu juhib autor Rootsi välisministeeriumi protokollitööd ning kandideerib ka parlamenti

Uurija Rita ja näitleja Elisabet / Jüri Laulik

Index Scriptorium Estoniae

Laulik, Jüri, 1959-

2006-01-01

ETV uues algupärases krimisarjas "Ohtlik lend" teeb kaasa ka Tallinna Linnateatri näitlejanna Elisabet Tamm. Sarja stsenarist on Mihkel Ulman, lavastaja Ain Prosa. Näitlejannast lähemalt. Sama : Teleleht, nr. 41, lk. 6-7 : ill

Poliitikas on palju võimalik / Väino Linde

Index Scriptorium Estoniae

Linde, Väino, 1959-

2005-01-01

Ilmunud ka: Vali Uudised, Meie Maa 1. apr. lk. 2, Koit 2. apr. lk. 6, Hiiu Leht 5. apr. lk. 2. Parlamendiliige lahkab momendi poliitilist olukorda, teeb ülevaate Riigikogu juhatuse valimisest ning usub Reformierakonna jätkamist valitsuskoalitsioonis

The development of logistics centres : important factor of increasing transport sector efficiency = Razvitije logistitsheskihh tsentrov : vazhnõi faktor uvelitshenija effektivnosti transportnogo sektora / Algirdas Sakalys

Index Scriptorium Estoniae

Sakalys, Algirdas

2003-01-01

Ettekanne 3.-4. detsembrini 2003 Tallinnas toimunud rahvusvahelisel konverents-näitusel "Logistics and transport in international trade" teeb ülevaate Leedu transpordisüsteemi olukorrast, arengustrateegiast ja reformidest, lähtudes Euroopa Liidu transpordipoliitika tegevuskavast. Kaardid. Diagramm. Tabel

Monkey Business toetab shimpansit / Sergo Selder

Index Scriptorium Estoniae

Selder, Sergo

2004-01-01

Moeturg teeb show'd Reval Park Hotelli & Casino heategevusüritusel. Osalevad tuntud tegijad Tiina Talumees Pärni, Triin Randloo, Kris Soonik ja noored moekunstnikud Triin Kärblane, Janina Pasti, Jana Einard. Kampaania on Tallinna loomaaia shimpansi Pino toetuseks

MIDA TEEB TEGEMA-VERB HOIDJAKEELES

Directory of Open Access Journals (Sweden)

Reili Argus

2010-01-01

Full Text Available Esimese keele omandamist mõjutab lapsele suunatud keel ehk hoidjakeel, mis pakub lapsele loomuliku keele sellise statistilise struktuuri, kus tõuseb esile mingi keelesüsteemiosa kõige sagedasem, üldisem, prototüüpsem, kesksem ning kõige lihtsam element. Hoidjakeeles esineb teistest verbidest sagedamini verbi tegema. Selle verbi ühendite hulk ja laad muutub lapse kasvades. Üldjoontes võib tegema-verbi tugiverbi konstruktsioonid lapsele suunatud kõnes jaotada kolme suuremasse rühma: kõige enam esineb selliseid ühendeid, kus tegema verbiga esineb koos mõni onomatopoeetiline sõna; tegema-verbi ja adverbi või adjektiivi ühendeid, millega rõhutatakse teelisust,leidub mõnevõrra vähem ning umbes neljandiku moodustavad tegema-verbi ja noomeni ühendid. Püsiühendite ja rutiniseerunud mallide suur hulk (moodustavad lapsele suunatud kõnes tegema-verbi konstruktsioonidest peaaegu poole annab alust oletada, et lapsega kõneleja eelistab kasutada n-ö valmis kujul keeletükke. Kuigi tegema-verbil on oma roll nii leksika kui ka süntaksi omandamises, ilmneb tema olulisus kõige selgemalt vormimoodustuse omandamise kontekstis: just sellest verbist esineb lapsele suunatud kõnes kõige enam eri vorme ning just see on üks kahest varakult omandatud vormimoodustusega verbe ka lapse kõnes.

BBC teeb Eestist Eurovisiooni-saadet

Index Scriptorium Estoniae

2002-01-01

Maailma tuntuim avalik-õigusliku tele- ja raadiokompanii British Broadcasting Corporation (BBC) ajakirjanikud käisid detsembri keskel Eestis, et teha pärast Eorovisiooni-võitu Eestist dokumentaalsaade

Vabadus teeb rikkaks / Andres Arrak

Index Scriptorium Estoniae

Arrak, Andres, 1958-2017

2005-01-01

Autor analüüsib Eesti majandusvabadust kahe edetabelipõhjal: ühte koostab alates 1996. aastast Kanadas asuv Frazeri Instituut, teist USA-s asuv Heritage Foundation ja majandusajakiri The Wall Street Journal. Diagramm: Majandusvabaduse indeksi muutus mullu Euroopa Liidus

Hansapank teeb õppelaenu taotlemise lihtsamaks

Index Scriptorium Estoniae

2000-01-01

Hansapangast õppelaenu soovivad üliõpilased saavad kontrollida internetipanga hanza.netìs, kas laenu saamiseks vajalikud tingimused on nende puhul täidetud ja esitada laenutaotluse hanza.netì või panga kodulehekülje kaudu : [täistekst] / DELFI-uudiseid vahendas Merike Määrits

ETV teeb Tartu vanglas tantsufilmi

Index Scriptorium Estoniae

2005-01-01

ETV-l valmib koos EFS-i ja Estinfilmiga kultuurikanali ARTE tellimusel tantsufilm "Teine" : režissöör Rene Vilbre : stsenarist Teet Kask : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir

Eesti-Ameerika ühisfilm lõpuks kohal

Index Scriptorium Estoniae

2001-01-01

Eilsest linastub kobarkinos Coca-Cola Plaza "Virtuoos" ("Out of the Cold") : režissöör Aleksandr Bulavsky : operaator Vladimir Klimov : peaosas Keith Carradine : Ameerika Ühendriigid - Eesti 1999. Väiksemates rollides teeb kaasa mitmeid eesti näitlejaid

Baltiiskii region i transportnaja ekologija = The Baltic region and transport ecology / Andrei Stepanov

Index Scriptorium Estoniae

Stepanov, Andrei

2004-01-01

Autor teeb ülevaate Läänemere ja Soome lahe keskkonnakaitse alastest algatustest, sh Helsingi konventsioonist, teaduslikust uurimistegevusest Venemaal, mille eesmärgiks on analüüsida ja vähendada meretranspordi ning sadamate tegevusega kaasnevat keskkonnaohtlikku mõju. Joonised

Võhma väike päkapikutöökoda / Jana Rand

Index Scriptorium Estoniae

Rand, Jana, 1963-

2005-01-01

Shveitslastest abielupaari Elke ja Peter Wüthrichi Võhmas asuvas firmas Sillacard valmistatavatest mitmetasapinnalistest kaartidest, mille kavandid teeb endine kunstiõpetaja Natalja Remmer. E. ja P. Wüthrichi pereettevõttes Gift Line tehakse küünlaid ja siiditrükki

Millest on tehtud arhitektuur? = What is architecture made of? / Indrek Rünkla

Index Scriptorium Estoniae

Rünkla, Indrek, 1971-

2009-01-01

Arhitekt Indrek Rünkla ettekujutus sellest, mida arhitekt teeb ja tegema peaks, ning ühiskonna vastav kujutus ei kattu. Ta püüab kirjeldada seda osa arhitektuurist, mis ühiskonna arhitektuuripildist välja tahab jääda

11th Animation Film Festival Animated Dreams : Animatheque

Index Scriptorium Estoniae

2009-01-01

Pimedate Ööde Filmifestivali alafestivali Animated Dreams lühitutvustus. Festival toimub 18. - 22. nov. 2009 Tallinnas. Alates 2008. aastast teeb festival koostööd Eesti Kunstiakadeemia Animatsiooni osakonnaga ja kord kuus toimuvad KUMU Auditooriumis animafilmide linastused programmis Animatheque

Tanel Padar osaleb dokumentaalfilmis / Verni Leivak

Index Scriptorium Estoniae

Leivak, Verni, 1966-

2001-01-01

USA plaadi- ja filmitootjafirma "insite" teeb filmi maailma noortest muusikutest "Rock the Planet", kes kommertsile lõivu maksmata hakkama püüavad saada. Üheks tegelaseks on režissöör eales Linton valinud ka Tanel Padari

Rakveres näeb uut teatrit

Index Scriptorium Estoniae

2003-01-01

Rakvere Teatris esineb 8. ja 9. aug. rahvusvaheline performance'i trupp Insightout Company, kus teeb kaasa ka Mari Mägi. Lavastus kannab pealkirja "Ära anda tulevik" ja see on inspireeritud trupi liikmete mälupiltidest ja I. Allende romaanist "Paula"

Teater annab ära tuleviku / Inna Grünfeldt

Index Scriptorium Estoniae

Grünfeldt, Inna, 1961-

2003-01-01

Rakvere Teatris esineb 8. ja 9. aug. rahvusvaheline performance'i trupp Insightout Company, kus teeb kaasa ka Mari Mägi. Lavastus kannab pealkirja "Ära anda tulevik" ja see on inspireeritud trupi liikmete mälupiltidest ja I. Allende romaanist "Paula"

Hea kultuuriantropoloog peab olema empaatiline / Kai Herkel ; intervjueerinud Reet Varblane

Index Scriptorium Estoniae

Herkel, Kai, 1963-

2009-01-01

Kai Herkeli Tiibeti-teemalisest näitusest "Himaalaja lapsed" Tallinna Linnagaleriis. Eksponeeritud fotod ja videod. Kai Herkel teeb Helsingi ülikooli sotsiaal- ja kultuuriantropoloogia erialal magistritööd lapsmunkade elust, oma kunstiprojektis on ta keskendunud Lamayuru kloostrikoolis õppivatele lapsmunkadele

Lipp lipi peal, lapp lapi peal / Valdo Randpere

Index Scriptorium Estoniae

Randpere, Valdo, 1958-

2006-01-01

IBM Eesti tegevdirektor teeb ettepaneku hakata Tallinna linnal tee- või ummikumaksu koguma, et linna tänavaid korras hoida ning liiklusummikuid hajutada. Ühtlasi soovitab autor teede-tänavate remondi planeerijail olla pisut mõistlikum ja ettenägelikum

Hamilton on surnud, tema mõju mitte : in memoriam Richard Hamilton (24. II 1922 - 13. IX 2011) / Kadri Karro ; kommenteerinud Eha Komissarov, Sirje Helme, Jaak Kangilaski

Index Scriptorium Estoniae

Karro,Kadri

2011-01-01

Briti kunstniku Richard Hamiltoni (1922 - 2011) loomingust eesti kunstiteadlaste Eha Komissarovi, Sirje Helme ja Jaak Kangilaski pilgu läbi. Lähemalt 1956. aastal valminud kollaažist "Mis teeb tänapäeva kodud nii eriliseks, nii meeldivaks?"

Filmitäht Johnny Depp hakkab Aleksandr Litvinenkost filmi tegema / M. P.

Index Scriptorium Estoniae

M. P.

2007-01-01

Populaarse näitleja Johnny Deppi filmistuudio Infinitum Nihil teeb põnevusfilmi näitlejaga peaosas vene hiljuti plutooniumimürgitusse surnud dissidentliku luuraja A. Litvinenko elust, aluseks veel ilmumata Alan Cowelli raamat "Sasha lugu : Vene spiooni elu ja surm"

Teerullitaktika kasutamisest riigieelarve arutamisel aastail 1998-2005 / Erkki Tori

Index Scriptorium Estoniae

Tori, Erkki

2007-01-01

Autor analüüsib Riigikogu nelja koosseisu kogemusi riigieelarve menetlemisel ning jõuab järeldusele, et valitsuskoalitsioonid on kasutanud teerullitaktikat ning teeb selle vähendamiseks ettepaneku muuta menetlusreeglistikku. Tabelid: 1998-2005. aasta riigieelarvesse esitatud ettepanekute edukus. Diagrammid, graafikud

Evaluación en campo de plantas de ñame (Dioscorea alata L. obtenidas de los microtubérculos formados en Sistema de Inmersión Temporal

Directory of Open Access Journals (Sweden)

Manuel Cabrera Jova

2010-01-01

Full Text Available Los microtubérculos en algunas especies de plantas constituyen una importante alternativa como material vegetal de plantación. Se definió como objetivo de trabajo evaluar en campo la respuesta morfoagronómica de las plantas obtenidas de los microtubérculos de ñame formados en Sistema de Inmersión Temporal (SIT. Como variantes experimentales se plantaron tres categorías de microtubérculos, clasificados según su masa fresca (I. de 0,5 a 0,9 g; II. de 1,0 a 2,9 g; III. igual o mayor de 3,0 g, plantas in vitro previamente aclimatadas y corona de tubérculo. Se evaluó el efecto de la masa fresca de los microtubérculos sobre su brote, supervivencia y posterior desarrollo de las plantas derivadas de ellos en campo. Con los microtubérculos de ñame, con una masa fresca igual o superior a 3,0 g, se alcanzó el más alto porcentaje de brotación (91,30% y supervivencia de las plantas (96,50%, así como las mejores respuestas en los caracteres cuantitativos que se evaluaron en campo. Estos resultados confirmaron la importancia de la masa fresca de los microtubérculos para ser empleados como material vegetal de plantación directo en campo.

Wind-tunnel investigation of the thrust augmentor performance of a large-scale swept wing model. [in the Ames 40 by 80 foot wind tunnel

Science.gov (United States)

Koenig, D. G.; Falarski, M. D.

1979-01-01

Tests were made in the Ames 40- by 80-foot wind tunnel to determine the forward speed effects on wing-mounted thrust augmentors. The large-scale model was powered by the compressor output of J-85 driven viper compressors. The flap settings used were 15 deg and 30 deg with 0 deg, 15 deg, and 30 deg aileron settings. The maximum duct pressure, and wind tunnel dynamic pressure were 66 cmHg (26 in Hg) and 1190 N/sq m (25 lb/sq ft), respectively. All tests were made at zero sideslip. Test results are presented without analysis.

My Video Collections / Marco Casagrande

Index Scriptorium Estoniae

Casagrande, Marco, 1971-

2006-01-01

Soome arhitekt ja kunstnik annab pika loendi oma videofilmide kollektsioonist, esitab subjektiivse filmide top 10-ne, mille esinumber on Andrei Tarkovski "Stalker". Teeb järelduse, et Tarkovski on talle kõige inspireerivam arhitekt, tema esitatud küsimused kõige suuremad

BBC võttis Eestis üles materjali Arvo Pärdi dokfilmi jaoks / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2009-01-01

BBC klassikalise muusika osakond teeb filmi klassikaliste heliloojate sarja jaoks. A. Pärdi kõrval käsitletakse filmis ka poola heliloojat Henryk Goreckit. Filmi režissöör on Simon Broughton ja moderaator tuntud näitleja Simon Russell-Beale

Reform : Keskerakonnal plaanis uus korteritehing

Index Scriptorium Estoniae

2007-01-01

Tallinna linnavolikogu otsusel ehitab OÜ Raadiku Arendus Tallinnale 1170 korterit ja annab need 20 aastaks linna kasutusse. Linnavolikogu Reformierakonna fraktsiooni esimehe Remo Holsmeri sõnul teeb kurioosseks otsuse see, et eelneva volikogu otsuse kohaselt korraldati hange eluruumide kasutusse võtmiseks 10 aastale

USAs tuleks bensiiniaktsiisi hoopis tõsta, mitte langetada / Kenneth Rogoff

Index Scriptorium Estoniae

Rogoff, Kenneth

2008-01-01

Autor leiab, et bensiiniaktsiisi tuleks tõsta, mitte langetada. Nafta hinda kõrgena hoides teeb OPEC keskkonna säilitamiseks rohkem kui lääne poliitikud, kes püüavad pikendada ökoloogiliselt jätkusuutmatut lääne tarbimiskultust

Tänavu hüppab börs nagu jänes. Aasta teine pool peaks investoreile rõõmsam olema / Romet Kreek

Index Scriptorium Estoniae

Kreek, Romet, 1972-

2011-01-01

Aasia maaklerfirma CLSA teeb alates 1992. aastast Hongkongis feng shui rikkuseindeksit, kus püütakse prognoosida, mida on saabunud aastal kuude lõikes Hongkongi börsil oodata ning milliste sektorite käsi võiks teistest paremini käia. Graafik

Kuppelkasvuhoonete disainer üllatab omapärase kunstnikukäega / Ille Grün-Ots

Index Scriptorium Estoniae

Grün-Ots, Ille, 1960-2016

2015-01-01

Kanadas sündinud ja Pärnumaal Lindil elav eestlane Robert Mart Sermat ehitab erilisi kuppelkasvuhooneid ja teeb veel originaalsemat kunsti, mida sai näha näitusel „Heavy Metal” Endla teatri Sammassaalis 27. märtsist kuni 19. aprillini

Deputat Riigikogu v bojevike v stilje kung-fu / Alina Zelimhanova

Index Scriptorium Estoniae

Zelimhanova, Alina

2005-01-01

Soome ja Hiina mütoloogiat ühendava fantaasiafilmi "Armuvalus sõdalane" (eelarve ca 40 milj. krooni, tootjad Soome, Holland, Hiina ja Eesti) võtted algavad täna Vihterpalu rabas. Kaasa teeb ka Elle Kull, lavastab debütant AJ Annila

Eestis algasid kung-fu-filmi võtted / Andri Maimets

Index Scriptorium Estoniae

Maimets, Andri, 1979-

2005-01-01

Soome ja Hiina mütoloogiat ühendava fantaasiafilmi "Armuvalus sõdalane" (eelarve ca 40 milj. krooni, tootjad Soome, Holland, Hiina ja Eesti) võtted algavad täna Vihterpalu rabas. Kaasa teeb ka Elle Kull, lavastab debütant AJ Annila

Alguses oli Piaf / Kaisa Karu

Index Scriptorium Estoniae

Karu, Kaisa

2010-01-01

Režissöör Christopher Nolani põnevusfilmis "Algus" (USA-Inglise 2010) teeb kaasa ka prantsuse näitleja Marion Cotillard. Tuntuks sai näitlejanna peaosaga režissöör Olivier Dahani filmis "Edith Piaf - elusse armunud"

Moskva ja Lääs enne Peterburi G-8 tippkohtumist / Urmas Kiil

Index Scriptorium Estoniae

Kiil, Urmas

2006-01-01

Hiljuti avalikustatud ettekannet Engaging with Russia - the Next Phase (Koostöö Venemaaga - järgmine etapp) võib pidada Venemaa ja lääneriikide suhete külmenemise mastaapseks kroonikaks ja see teeb problemaatiliseks Venemaa edaspidise osalemise G-8 seltskonnas

Kas internet muudab meid rumalamaks? / Liis Kängsepp

Index Scriptorium Estoniae

Kängsepp, Liis, 1981-

2012-01-01

Raamatust: Carr, Nicholas. Triiv madalikule : mida Internet meie ajuga teeb / tõlkija Tiina Randus. Tallinn : Äripäev, 2012. (Äripäeva raamat). Ka intervjuu Tallinna Ülikooli dotsendi Kristjan Pordiga raamatus esitatud väidetest interneti mõjust inimesele

Poliitikud peavad saadiku hüvesid lahjaks / Kaire Uusen

Index Scriptorium Estoniae

Uusen, Kaire

2006-01-01

Ilmunud ka: Postimees : na russkom jazõke 7. apr. lk. 5. Riigikogu uue esimehe Toomas Vareki sõnul teeb talle muret Riigikogu liikmete sage vahetumine, mille üheks põhjuseks on poliitikute hinnangul parlamendisaadiku ebapiisavad hüved. Lisa: Riigikogulaste hüved

Oh oleksin ma rikas! : [luuletused] / Hans Christian Andersen ; tlk. Harald Rajamets

Index Scriptorium Estoniae

Andersen, Hans Christian, 1805-1875

2004-01-01

Sisu: Oh oleksin ma rikas! ; Tädi prillid ; "Oh vägev surm, sa külvad tummalt õudu..." ; "Meil maa peal elu kurblik näib..." ; "Kõik kaob nagu tuul siin ära..." ; "Lund on veel maas ja vahel teeb tuisku..."

BLRT ostis Läänemere suurima laevaremontija / Lauri Linnamäe

Index Scriptorium Estoniae

Linnamäe, Lauri

2007-01-01

Ilmunud ka: Postimees : na russkom jazõke, 7. juuni 2007, lk. 5. Laevatehas BLRT Grupp ostis Läänemere suurima kuivdokiga Soome laevaremonditehase, Naantalis asuva Turku Repair Yard Ltd, mis teeb BLRT-st piirkonna ühe suurima laevaremontija. Lisa: Mis on BLRT?

Eelisaktsiate kajastamisest ehk milles Raamatupidamise Toimkond ja PricewaterhouseCoopers eksivad ja eelmisel Raamatupidamise Toimkonnal siiski õigus oli / Jaan Alver

Index Scriptorium Estoniae

Alver, Jaan, 1949-

2004-01-01

Autor selgitab eelisaktsiate olemust, toob välja eelisaktsia ning lihtaktsia ja pikaajalise võlakirja peamised erinevused ning teeb ülevaate rahvusvahelises standardis IAS 32 eelisaktsiate klassifitseerimise kohta sisalduvast. Tabelid: Lihtaktsiate ja eelisaktsiate võrdlus; Pikaajaliste võlakirjade ja eelisaktsiate võrdlus

Alternative treatments in international financial reporting standards / Madis Jääger

Index Scriptorium Estoniae

Jääger, Madis, 1980-

2003-01-01

Rahvusvahelised raamatupidamisstandardid võimaldavad kasutada erinevaid arvestusmetoodikaid, mille abil on võimalik mõjutada ettevõtte finantsolukorra tulemuste esitamist.Autor arvutab erinevaid raamatupidamisprotseduure kasutades ettevõtte puhaskasumit, mille erinevatest tulemustest johtuvalt teeb järelduse raamatupidamisaruandluse standardiseerimise ja harmoniseerimise vajalikkusest. Tabelid. Diagrammid

Jutta Rabe esitles filmi Estoniast / Heiki Suurkask

Index Scriptorium Estoniae

Suurkask, Heiki, 1972-

2002-01-01

Saksamaal demonstreeriti esimesi kaadreid poliitilisest põnevusfilmist "Balti torm" ("Baltic Storm"), mis kujutab parvlaev "Estonia" hukku venelaste vandenõu tulemusena. Produtsendid on Jutta Rabe ja Kaj Holmberg, peaosades Greta Scacchi ja Jürgen Prochnow. Kaasa teeb ka Donald Sutherland USA kindrali rollis

U sovremennogo Buratino ne papa, a mama Karlo / Svetlana Karabut

Index Scriptorium Estoniae

Karabut, Svetlana

2008-01-01

Režissöör Rasmus Merivoo teeb oma esimest täispikka mängufilmi. Laste- ja noortefilmi "Buratino" stsenaristid on Rasmus Merivoo ja Kristin Kalamees. Filmivõtted algasid 1. juulil, film valmib Eesti ja Venemaa koostööna

Mutagens from the cooking of food. II. Survey by Ames/Salmonella test of mutagen formation in the major protein-rich foods of the American diet

Energy Technology Data Exchange (ETDEWEB)

Bjeldanes, L.F. (Univ. of California, Berkeley); Morris, M.M.; Felton, J.S.; Healy, S.; Stuermer, D.; Berry, P.; Timourian, H.; Hatch, F.T.

1982-01-01

The formation of mutagens in the major cooked protein-rich foods in the US diet was studied in the Ames Salmonella typhimurium test. The nine protein-rich foods most commonly eaten in the USA--ground beef, beef steak, eggs, pork chops, fried chicken, pot-roasted beef, ham, roast beef and bacon--were examined for their mutagenicity towards S. typhimurium TA1538 after normal 'household' cooking (deep frying, griddle/pan frying, baking/roasting, broiling, stewing, braising or boiling at 100-475/sup 0/C). Well-done fried ground beef, beef steak, ham, pork chops and bacon showed significant mutagen formation. For chicken and beef steak high-temperature broiling produced the most mutagenicity, followed by baking/roasting and frying. Stewing, braising and deep frying produced little mutagen. Eggs andd egg products produced mutagens only after cooking at high temperatures (the yolk to a greater extent than the white). Commercially cooked hamburgers showed a wide range of mutagenic activity. We conclude that mutagen formation following cooking of protein-containing foods is a complex function of food type, cooking time and cooking temperature. It seems clear that all the major protein-rich foods if cooked to a well-done state on the griddle (eggs only at temperature above 225/sup 0/C) or by broiling will contain mutagens detectable by the Ames/Salmonella assay. This survey is a step towards determining whether any human health hazard results from cooking protein-rich foods. Further testing in both short- and long-term genotoxicity bioassays and carcinogenesis assays are needed before any human risk extrapolations can be made.

Mutagens from the cooking of food. II. Survey by Ames/Salmonella test of mutagen formation in the major protein-rich foods of the American diet.

Science.gov (United States)

Bjeldanes, L F; Morris, M M; Felton, J S; Healy, S; Stuermer, D; Berry, P; Timourian, H; Hatch, F T

1982-08-01

The formation of mutagens in the major cooked protein-rich foods in the US diet was studied in the Ames Salmonella typhimurium test. The nine protein-rich foods most commonly eaten in the USA--ground beef, beef steak, eggs, pork chops, fried chicken, pot-roasted beef, ham, roast beef and bacon--were examined for their mutagenicity towards S. typhimurium TA1538 after normal 'household' cooking (deep frying, griddle/pan frying, baking/roasting, broiling, stewing, braising or boiling of 100-475 degrees C). Well-done fried ground beef, beef steak, ham pork chops and bacon showed significant mutagen formation. For chicken and beef steak high-temperature broiling produced the most mutagenicity, followed by baking/roasting and frying. Stewing, braising and deep frying produced little mutagen. Eggs and egg products produced mutagens only after cooking at high temperatures (the yolk to a greater extent than the white). Commercially cooked hamburgers showed a wide range of mutagenic activity. We conclude that mutagen formation following cooking of protein-containing foods is a complex function of food type, cooking time and cooking temperature. It seems clear that all the major protein-rich foods if cooked to a well-done state on the griddle (eggs only at temperatures above 225 degrees C) or by broiling will contain mutagens detectable by the Ames/Salmonella assay. This survey is a step towards determining whether any human health hazard results from cooking protein-rich foods. Further testing in both short- and long-term genotoxicity bioassays and carcinogenesis assays are needed before any human risk extrapolations can be made.

Comparative mutability of the Ames tester strains of Salmonella typhimurium by ultraviolet radiation and by 4-nitroquinoline I-oxide

International Nuclear Information System (INIS)

Nakano, E.; Ichikawa-Ryo, H.; Kondo, S.

1982-01-01

A standard method for determining mutant frequencies per survivor was used to study the detailed kinetics of reverse mutations of Ames tester strains of Salmonella typhimurium induced by UV and by 4NQO. After UV irradiation, strain TA1538 was non-mutable, but its plasmid-containing derivative TA98 was mutable, whereas TA1535 was mutable and its plasmid-bearing derivative TA100 was about 10-fold more mutable. After treatment with 4NQO, TA98 was less mutable than TA1538, whereas TA100 was more mutable than TA1535 by a factor of 10-50. TA1537 was slightly less mutable than TA1535 by either UV or 4NQO. The differential mutabilities of these strains are briefly discussed in relation to the 'hot spot' base sequences for reversion and the nature of DNA damage caused by UV and 4NQO. (orig.)

I. The properties of hot Ca-like fragments from the 40Ca+40Ca reaction at 35 AMeV

International Nuclear Information System (INIS)

Planeta, R.; Gawlikowicz, W.; Wieloch, A.

2001-01-01

The creation of hot Ca-like fragments was investigated in the 40 Ca + 40 Ca reaction at 35 AMeV. Using the AMPHORA 4π detector system, the primary projectile-like fragment was reconstructed and its properties were determined. Both primary and secondary distributions are compared with the predictions of a Monte Carlo code describing a heavy-ion collision as a two-step process. Some of the nucleons which are identified as participants in the first step are transferred in the second step to these final states, which correspond on the average to the maximum value of entropy (thermodynamic probability). The model allows for competition between mean-field effects and nucleon-nucleon interactions in the overlap zone of the interacting nuclei. The analysis presented here suggests a thermalized source picture of the decay of the projectile-like fragment. The validity of the reconstruction procedure for projectile-like fragments is discussed. (orig.)

Mutagenicity and antimutagenicity of Salacia crassifolia (mart. Ex. Schult. G. Don. evaluated by Ames test

Directory of Open Access Journals (Sweden)

C. C. Carneiro

2017-09-01

Full Text Available Abstract Salacia crassifolia (Mart. Ex. Schult. G. Don. is a bush which belongs to Celastraceae family and occurs specially in Brazilian Cerrado. Its leaves, stem, seeds and fruits are popularly used for several medicinal purposes, such as antitumoral, antirheumatic, anti-inflammatory and antimicrobial. In this study, the mutagenic and antimutagenic activities of S. crassifolia stem bark fractions (hexane, ethyl acetate and hydroalcoholic were evaluated by the Ames mutagenicity assay in Salmonella typhimurium TA98 and TA100 strains. By the obtained results, all S. crassifolia fractions did not significantly increase the number of prototrophic revertants for histidine (His+ in both S. typhimurium strains tested (p > 0.05, suggesting absence of mutagenicity. Regarding antimutagenicity, the fractions ethyl acetate and hydroalcoholic significantly decreased the number of His+ revertants colonies induced by positive control for strain TA98 (p < 0.05, demonstrating protection against mutagenicity induced by 4-nitroquinolile1-oxide, whereas the hexane fraction did not show antimutagenic effect in this strain. In the TA100 strain, all fractions of S. crassifolia protected DNA against the harmful action of sodium azide, and the hexane fraction exhibited the greatest protection in this work. Thus, it’s possible conclude that the fractions of S. crassifolia tested in this study could be used in chemoprevention.

Multiplicación in vitro de segmentos nodales del clon de ñame Blanco de Guinea (Dioscorea cayenensis - D. rotundata ) en sistemas de cultivo semiautomatizado

OpenAIRE

Manuel Cabrera Jova; Rafael Gómez Kosky; Sergio Rodríguez Morales; Jorge López Torres; Aymé Rayas Cabrera; Milagros Basail Pérez; Arletys Santos Pino; Víctor Medero Vega; Germán Rodríguez Rodríguez

2009-01-01

Con el empleo del sistema de inmersión temporal fue posible incrementar la multiplicación in vitro de los segmentos nodales en el clon de ñame Blanco de Guinea. Con este tipo de sistema de cultivo se obtuvieron los más altos valores para la altura de la planta, número de entrenudos por planta, así como para la masa fresca y seca de las mismas. Las condiciones de cultivo creadas en el sistema de inmersión temporal para la multiplicación in vitro de los segmentos nodales lograron el más alto co...

Sources and levels of background noise in the NASA Ames 40- by 80-foot wind tunnel

Science.gov (United States)

Soderman, Paul T.

1988-01-01

Background noise levels are measured in the NASA Ames Research Center 40- by 80-Foot Wind Tunnel following installation of a sound-absorbent lining on the test-section walls. Results show that the fan-drive noise dominated the empty test-section background noise at airspeeds below 120 knots. Above 120 knots, the test-section broadband background noise was dominated by wind-induced dipole noise (except at lower harmonics of fan blade-passage tones) most likely generated at the microphone or microphone support strut. Third-octave band and narrow-band spectra are presented for several fan operating conditions and test-section airspeeds. The background noise levels can be reduced by making improvements to the microphone wind screen or support strut. Empirical equations are presented relating variations of fan noise with fan speed or blade-pitch angle. An empirical expression for typical fan noise spectra is also presented. Fan motor electric power consumption is related to the noise generation. Preliminary measurements of sound absorption by the test-section lining indicate that the 152 mm thick lining will adequately absorb test-section model noise at frequencies above 300 Hz.

Rossiiskim gruzam - rossiiskije konteinerõ = Russian containers for Russian cargoes / Alla Petrova

Index Scriptorium Estoniae

Petrova, Alla

2004-01-01

Autor teeb ülevaate transpordisüsteemi arengust, konteinerite tootmisest ja konteinervedude korraldusest NSV Liidus alates 1970ndatest ning analüüsib põhjuseid, miks käesoleval ajal tegelevad Venemaal konteinervedudega valdavalt välisfirmad kasutades läänes toodetud konteinereid

Stanford aitab Eestit tutvustada

Index Scriptorium Estoniae

2011-01-01

Tallinna okupatsioonide muuseumi rahastav Kistler-Ritso fond teeb miljonite dollarite suuruse annetuse USAs asuva Stanfordi ülikooli fondile. Üks sihtotstarve on Eesti ajaloo dokumentide digitaliseerimine. Kistler-Ritso Eesti Sihtasutuse liikmeks kutsuti ka president Toomas Hendrik Ilvese poeg, Stanfordi ülikooli vilistlane Luukas Ilves

Stanfordi ülikool aitab Eesti ajalugu üle ilma tutvustada / Heidit Kaio

Index Scriptorium Estoniae

Kaio, Heidit, 1971-

2011-01-01

Tallinna okupatsioonide muuseumi rahastav Kistler-Ritso fond teeb miljonite dollarite suuruse annetuse USAs asuva Stanfordi ülikooli fondile. Üks sihtotstarve on Eesti ajaloo dokumentide digitaliseerimine. Kistler-Ritso Eesti Sihtasutuse liikmeks kutsuti ka president Toomas Hendrik Ilvese poeg, Stanfordi ülikooli vilistlane Luukas Ilves

Muuseumihoone autorid : minevikuga tuleb silmitsi seista / Tsuyoshi Tane, Lina Ghotmeh, Dan Dorell ; interv. Ave Randviir

Index Scriptorium Estoniae

Tane, Tsuyoshi

2006-01-01

Eesti Rahva Muuseumi arhitektuurivõistluse võiduprojekti autorid Tsuyoshi Tane, Lina Ghometh ja Dan Dorell omavahelisest koostööst, võistlustööst, vastuseid kriitikale. Teistest premeeritud projektidest. Ave Randviiru kommentaar "Võidutöö teeb ajaloole psühhoanalüüsi"

I Pol Makkartni v podarok / Aleksei Shipulin ; interv. Jelena Skulskaja

Index Scriptorium Estoniae

Shipulin, Aleksei

2004-01-01

Moskvas elav Eesti kodanikust dokumentalist teeb Eestis vene telekanalile "Kultura" dokumentaalfilmi Lennart Merist. Režissöör jutustab ka oma varasematest filmidest nagu "Paul McCartney. 72 tundi Venemaal" ("Pol Makkartni. 72 tshassa v Rossii") ja "Serõi voronok. Komu tõ nuzhen?"

Elo Viidingu kommentaarid Berk Vaheri kommentaarile / Elo Viiding

Index Scriptorium Estoniae

Viiding, Elo, 1974-

2001-01-01

Vt. ka Vaher, Berk. Mis teeb tuul müürile? : repriis Elo Viidingu sõnavõtule "Uued tuuled, vana vaev" (Looming 12/2000) // Sirp (2001) 12. jaan., lk. 6. Vastukaja: Vaher, Berk. Berk Vaheri kommentaarid Elo Viidingu kommentaaridele // Sirp (2001) 19. jaan., lk. 13

Carl Bildt : Gruusia edu põhineb Eesti eeskujul / Carl Bildt ; interv. Holger Roonemaa

Index Scriptorium Estoniae

Bildt, Carl, 1949-

2006-01-01

Rootsi välisminister peab Gruusia puhul kõige tähtsamaks reformide jätkumist. Venemaal ja Gruusial tuleks oma erimeelsustest üle saada, EL ootab Venemaalt kinnitust Gruusia territoriaalse puutumatuse kohta. Vene-Saksa gaasijuhtme rajamisel teeb Rootsile muret peamiselt selle projekti keskkonnaohtlikkus

Ausad vaesed, laiskus ja võitlev feminism / Hillar Padu

Index Scriptorium Estoniae

Padu, Hillar

2002-01-01

Inglise filosoof, loogik ja ühiskonnategelane Bertrand Russell (1872-1970) väitis, et usk töö moraalsusesse teeb tänapäeva maailmas palju kurja ja et tee õnnele ja jõukusele seisneb plaanipärase töö vähendamises

Odaval valuutal mitu eelist / Dani Rodrik

Index Scriptorium Estoniae

Rodrik, Dani

2007-01-01

Ilmunud ka: Molodjozh Estonii 14. aug. lk. 7. Arenevate majanduste ees seisvast tähtsamast majanduspoliitilisest dilemmast: ühest küljest nõuab pidev majanduskasv konkurentsivõimelist valuutat, teisest küljest heade majandusuudiste puhul tuleb tõsta valuutakurssi, mis teeb konkurentsivõimelisuse keeruliseks

Kliima ja rahvusvaheline julgeolek : uus üleilmne väljakutse / Javier Solana

Index Scriptorium Estoniae

Solana, Javier

2008-01-01

EL-i ühise välis- ja julgeolekupoliitika kõrge esindaja esitleb koos Euroopa Komisjoniga aruannet Euroopa riikide ja valitsuste juhtidele kliimamuutustest põhjustatud riskide kohta. Autor toob välja kolm ähvardust, mida esitab kliimamuutus, ning teeb ka kolm ettepanekut kliimamuutustega toimetulekuks

Eesti osaleb suurejoonelises filmiprojektis

Index Scriptorium Estoniae

pPIK mare 2010

2004-01-01

Filmiprojekt tööpealkirjaga "Generation", mis on plaanitud täispikaks mängufilmilaadseks filmiks. Tegemisse on kaasatud kuus noort režissööri Ida-Euroopast. Eestit esindab animafilmide režissöör Mait Laas, kes teeb valmivale filmile raamjutustuse

Proovid kinnitavad bensiini tootmist / Kadri Ibrus

Index Scriptorium Estoniae

Ibrus, Kadri

2006-01-01

Tanker Probo Koala nn solkvesi sisaldab mürgiseid elemente, mis on tekkinud naftaprotsesside töötlemise tagajärjel. Tallinnasse jõudnud Elevandiluuranniku delegatsioon, mille juht on riigi peaprokurör, teeb koostööd Eesti prokuratuuriga. Lisa: Võrdlevad ekspertiisi tulemusi

Baltic Storm'i tagasihoidlik edu / Jürgen-Friedrich Laulik

Index Scriptorium Estoniae

Laulik, Jürgen-Friedrich

2003-01-01

Saksa ajakirjanduse vastukajasid Berliinis esilinastunud poliitilisele põnevusfilmile "Balti torm" ("Baltic Storm"), mis kujutab parvlaev "Estonia" hukku. Režissöör ja üks stsenariste on Reuben Leder, peaosades Greta Scacchi ja Jürgen Prochnow. Kaasa teeb ka Donald Sutherland USA kindrali rollis

11. september 2001 heiastub viis aastat hiljem filmilindil / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2006-01-01

Paul Greengrass teeb USA-s mängufilmi "United 93" sündmustest lennukis, mis pidi terroristide soovil sööstma kas Valgesse Majja või Kapitooliumi. Oliver Stone'l on valmimas film Nicolas Cage'i ja Michael Penaga pealkirjaga "World Trade Center"

Zara - Euroopa rõivakaubanduse täht / Marge Rahu

Index Scriptorium Estoniae

Rahu, Marge

2003-01-01

Autor teeb ülevaate Hispaania rõivaettevõtte Inditex tuntuimast kaubamärgist Zara, ettevõtte tegevusest rahvusvahelistel turgudel ja jaekaubanduskontseptsioonidest. Autor tutvustab Eesti rõivatööstusettevõtte Baltika uut strateegiat muutuda tootjast kaupmeheks, mida viiakse ellu kaubamärgi Monton abil

The ecosystem services agenda: bridging the worlds of natural science and economics, conservation and development, and public and private policy

NARCIS (Netherlands)

Braat, L.C.; Groot, de R.S.

2012-01-01

The Ecosystem Services Journal starts in 2012 with a formidable basis in the reports and books from the Millennium Ecosystem Assessment and TEEB projects. Following a half-century history of growing awareness and associated scientific based policy development a bridging concept with natural and

Endel Siff napsas Kopli liinid Oliver Kruuda eest / Krista Taim

Index Scriptorium Estoniae

Taim, Krista

2006-01-01

Endel Sifi firma Primos võitis konkursil Kopli liinidel asuva 16,8 ha suuruse maa-ala hoonestusõiguse. Vt. samas: Ober-Haus: projekt on perspektiivikas; Siff sihib lisaks Kopli arendamisele Lasnamäe karjääri; Kruuda: teiseks jäämine teeb meele kurvaks

Davidid tahavad lennata / Mari Peegel

Index Scriptorium Estoniae

Peegel, Mari, 1978-

2010-01-01

Uuest Saksamaa dokumentaalfilmist "David Wants to Fly", kus režissöör David Sieveking uurib transtsendentaalse meditatsiooni ärisaladusi. TM-ist teeb filmi ka USA režissöör David Lynch, kes 2007. aastal jõudis oma TM-i reklaamiva turneega ka Tallinna

Симонов: играть надо всегда радостно / Ксения Репсон

Index Scriptorium Estoniae

Репсон, Ксения

2011-01-01

Festivali Kuldne mask Eestis raames etendub Gerard Sibleyrasi absurdikomöödia "Ветер шумит в тополях" (Moskva Jevgeni Vahtangovi nim. Teater), lavastaja Rimas Tuminas. Lavastuses teeb kaasa Venemaa näitleja Vladimir Simonov

Poodidele omamärgikraami tegemine säästab kulusid / Ketlin Priilinn

Index Scriptorium Estoniae

Priilinn, Ketlin, 1982-

2008-01-01

Poeketid on üha enam hakanud müüma kaupu oma kaubamärgi all. Vt. samas: Jaemüügiketti omamärgitoode ehk private label. Diagramm: Omamärk teeb Euroopas võidukäiku. Kommenteerivad Kristjan Alaküla ja Ott Licht

Tagasisidet peab töötajale vahendama ülemus / Mait Raava

Index Scriptorium Estoniae

Raava, Mait

2004-01-01

Autor teeb lühiülevaate 360ʻ ja teiste tagasiside meetodite rakendamisest maailmas alates 1950ndatest aastatest ning juhib tähelepanu vigadele, mida meetodi rakendamisel on tehtud. Kommenteerib Irene Metsis. Skeem: Juht saab tagasiside nelja kanali kaudu. Vt. samas: Rollist tulenevalt on tagasiside erinev

Õppivale õpetajale saaks leida asendaja väljastpoolt kooli / Krista Noorkõiv

Index Scriptorium Estoniae

Noorkõiv, Krista

2001-01-01

27. sept.̀2001 peeti Brüsselis konverents "Learning Economy and Jobrotation". Arutati täiendusõppe sellist süsteemi, kus õppima suunatud inimese asemel teeb tema töö ära asendustöötaja (leitud sageli sama eriala töötute hulgast)

Baltics to cash in on reality-based TV craze / Jaclyn M. Sindrich

Index Scriptorium Estoniae

Sindrich, Jaclyn M.

2000-01-01

TV 3 teeb ühel Läänemere laiul meelelahutuslikku dokumentaalsarja "Robinson" suletud keskkonnas viibivate tavaliste inimeste omavaheliste suhete ning hakkamasaamisoskuse näitamiseks, Kanal 2 jälgib tõsielusarjas "112" Nõmme komando päästjate-tuletõrjujate ja parameedikute tööd

Sami Seppänen : kõnehinna langus hakkab otsa saama / Sami Seppänen ; interv. Henrik Ilves

Index Scriptorium Estoniae

Seppänen, Sami

2007-01-01

Elisa juhatuse esimehe hinnangul halvab hindade tõstmine ja siis ümberotsustamine mulje kogu mobiilside tegevusalast. Elisa ei kaalunud võimalust EMT sammuga - võtta kasutusele minutipõhine kõnearvestus - kaasa minna, kuid pole välistatud, et tulevikus Elisa seda teeb. Lisa: Konkurendid on sama meelt

Genotoxic, Cytotoxic, Antigenotoxic, and Anticytotoxic Effects of Sulfonamide Chalcone Using the Ames Test and the Mouse Bone Marrow Micronucleus Test.

Directory of Open Access Journals (Sweden)

Carolina Ribeiro E Silva

Full Text Available Chalcones present several biological activities and sulfonamide chalcone derivatives have shown important biological applications, including antitumor activity. In this study, genotoxic, cytotoxic, antigenotoxic, and anticytotoxic activities of the sulfonamide chalcone N-{4-[3-(4-nitrophenylprop-2-enoyl]phenyl} benzenesulfonamide (CPN were assessed using the Salmonella typhimurium reverse mutation test (Ames test and the mouse bone marrow micronucleus test. The results showed that CPN caused a small increase in the number of histidine revertant colonies in S. typhimurium strains TA98 and TA100, but not statistically significant (p > 0.05. The antimutagenicity test showed that CPN significantly decreased the number of His+ revertants in strain TA98 at all doses tested (p 0.05. Additionally, CPN co-administered with MMC significantly increased PCE/NCE ratio at all doses tested, demonstrating its anticytotoxic effect. In summary, CPN presented genotoxic, cytotoxic, antigenotoxic, and anticytotoxic properties.

Full-Span Tiltrotor Aeroacoustic Model (TRAM) Overview and 40- by 80-Foot Wind Tunnel Test. [conducted in the 40- by 80-Foot Wind Tunnel at Ames Research Center

Science.gov (United States)

McCluer, Megan S.; Johnson, Jeffrey L.; Rutkowski, Michael (Technical Monitor)

2001-01-01

Most helicopter data trends cannot be extrapolated to tiltrotors because blade geometry and aerodynamic behavior, as well as rotor and fuselage interactions, are significantly different for tiltrotors. A tiltrotor model has been developed to investigate the aeromechanics of tiltrotors, to develop a comprehensive database for validating tiltrotor analyses, and to provide a research platform for supporting future tiltrotor designs. The Full-Span Tiltrotor Aeroacoustic Model (FS TRAM) is a dual-rotor, powered aircraft model with extensive instrumentation for measurement of structural and aerodynamic loads. This paper will present the Full-Span TRAM test capabilities and the first set of data obtained during a 40- by 80-Foot Wind Tunnel test conducted in late 2000 at NASA Ames Research Center. The Full-Span TRAM is a quarter-scale representation of the V-22 Osprey aircraft, and a heavily instrumented NASA and U.S. Army wind tunnel test stand. Rotor structural loads are monitored and recorded for safety-of-flight and for information on blade loads and dynamics. Left and right rotor balance and fuselage balance loads are monitored for safety-of-flight and for measurement of vehicle and rotor aerodynamic performance. Static pressure taps on the left wing are used to determine rotor/wing interactional effects and rotor blade dynamic pressures measure blade airloads. All of these measurement capabilities make the FS TRAM test stand a unique and valuable asset for validation of computational codes and to aid in future tiltrotor designs. The Full-Span TRAM was tested in the NASA Ames Research Center 40- by 80-Foot Wind Tunnel from October through December 2000. Rotor and vehicle performance measurements were acquired in addition to wing pressures, rotor acoustics, and Laser Light Sheet (LLS) flow visualization data. Hover, forward flight, and airframe (rotors off) aerodynamic runs were performed. Helicopter-mode data were acquired during angle of attack and thrust sweeps for

Teel koolisüsteemi ühtsuse poole / Tõnis Lukas

Index Scriptorium Estoniae

Lukas, Tõnis, 1962-

2007-01-01

Haridusminister selgitab, kuidas pakkuda lastele senisest paremaid ja võrdsemaid võimalusi hariduse omandamiseks, kuidas toimub venekeelsete koolide üleminek eestikeelsele õppele ning teeb ettepaneku moodustada tipptasemel nn. puhas gümnaasium ning senised 63 väiksemat venekeelset gümnaasiumi liita kümmekonnaks gümnaasiumiks

MILREM extends THeMIS mission set / Huw Williams

Index Scriptorium Estoniae

Williams, Huw

2016-01-01

Eesti kaitsetehnika ettevõte MILREM OÜ täiendab oma relvasüsteemi THeMIS ja teeb selleks koostööd mitmete firmadega. Tulevikus soovitakse lisaks Eesti kaitseväele teha koostööd ka Läti kaitseväega ja kasutada sõjatehnikat sealsetel õppustel

Bookinghouse peatas Air Balticu piletite müügi / Ann-Marii Nergi

Index Scriptorium Estoniae

Nergi, Ann-Marii

2011-01-01

Lennupiletite vahendamisega tegelev Leedu portaal Bookinghouse peatas 27. juunil makseraskustes vaevleva Läti lennundusfirma Air Balticu piletite müügi, põhjendades seda Läti lennufirma finantsseisu kohta avalikuks tulnud infoga. Air Baltic väidab, et Bookinghouse on korduvalt reisijatele valeinformatsiooni jaganud ja teeb seda ka praegu

Nõo lihatööstus läheb Venemaale ettevaatlikult / Vilja Kohler

Index Scriptorium Estoniae

Kohler, Vilja, 1966-

2005-01-01

Tartumaa toiduainetefirmadest said Venemaa ekspordiloa AS Beetak, AS Nõo Lihatööstus, AS Kallaste Kalur, OÜ Põltsamaa Meierei Juustutööstus ja AS Valio Eesti Laeva Meierei. Esimesed proovipartiid on Venemaale saatnud kalafirma AS Beetak, ettevalmistusi ekspordiks teeb AS Nõo Lihatööstus. Lisa: Toit Venemaale

Changes in Estonian organisations / Ruth Alas

Index Scriptorium Estoniae

Alas, Ruth, 1960-2018

2003-01-01

Kaanel ajak. ilmumisaeg 2002/2003. Autor teeb ülevaate organisatsiooniliste muudatuste tüüpe käsitlevatest teooriatest, analüüsib Eesti ettevõtetes läbiviidud empiirilise uuringu tulemusi ümberkorraldusprotsesside kohta ja tutvustab Eesti ettevõtlusele sobivat 4-astmelist organisatsiooniliste muutuste mudelit. Tabelid. Skeem

Фильм о людях снимавших фильмы / Игорь Минаев ; интервьюировала Инга Домбровская

Index Scriptorium Estoniae

Минаев, Игорь

2009-01-01

Vene filmirežissööri Igor Minajevi, kes elab ja töötab Prantsusmaal, mängufilmi "Kaugel Sunset-Boulevard'ist" näeb 31. märtsil Tallinnas Vene Kultuurikeskuses. Režissöör oma filmist, milles teeb kaasa ka Lembit Ulfsak

Exploring reaction mechanisms and their competition in 58Ni+48Ca collisions at E = 25 AMeV

Directory of Open Access Journals (Sweden)

Francalanza L.

2014-03-01

Full Text Available Latest results concerning the study of central collisions in 58Ni+48Ca reactions at Elab(Ni=25 AMeV are presented. The experimental data, collected with the CHIMERA 4π device, have been analyzed in order to investigate the competition among different reaction mechanisms for central collisions in the Fermi energy domain. The method adopted to perform the centrality selection refers to the global variable “flow angle”, that is related to the event shape in momentum space, as it is determined by the eigenvectors of the experimental kinetic-energy tensor. The main features of the reaction products were explored by using different constraints on some of the relevant observables, such as mass and velocity distributions and their correlations. Much emphasis was devoted to the competition between fusion-evaporation processes with subsequent identification of a heavy residue and a prompt multifragmentation mechanism. The reaction mechanism was simulated in the framework of transport theories (dynamical stochastic BNV calculations, followed by sequential SIMON code and further comparison with dynamical calculations from transport model (QMD, CoMD are in progress. Moreover, an extension of this study taking into account for the light particles has been envisaged.

Measurement of isotopic cross sections of the fission fragments produced in 500 AMeV {sup 208}Pb + p reaction; Etude de la production des fragments de fission issus de la reaction {sup 208}Pb + p a 500 AMeV

Energy Technology Data Exchange (ETDEWEB)

Fernandez-Dominguez, B

2003-03-01

The aim of this work is the study of the fission fragments produced in the spallation reaction {sup 208}Pb + p at 500 AMeV. The fission fragments from Z=23 up to Z=59 have been detected and identified by using the inverse kinematics technique with the high-resolution spectrometer FRS. The production cross sections and the recoil velocities of 430 nuclei have been measured. The measured data have been compared with previous data. The isotopic distributions show a high precision. However, the absolute value of the fission cross section is higher than expected. From the experimental data the characteristics of the average fissioning system have been reconstructed (Z{sub fis}, A{sub fis}, E*{sub fis}). In addition, the number of post-fission neutrons emitted from the fission fragments, v{sub post}, has been determined by using a new method. The experimental data have been compared to the two-steps models describing the spallation reaction. The impact of the model parameters on the observables has been analysed and the reasons Leading to the observed differences between the codes are also presented. This analyse shows a good agreement with the INCL4+ABLA code. (author)

MicroRNA regulation in Ames dwarf mouse liver may contribute to delayed aging.

Science.gov (United States)

Bates, David J; Li, Na; Liang, Ruqiang; Sarojini, Harshini; An, Jin; Masternak, Michal M; Bartke, Andrzej; Wang, Eugenia

2010-02-01

The Ames dwarf mouse is well known for its remarkable propensity to delay the onset of aging. Although significant advances have been made demonstrating that this aging phenotype results primarily from an endocrine imbalance, the post-transcriptional regulation of gene expression and its impact on longevity remains to be explored. Towards this end, we present the first comprehensive study by microRNA (miRNA) microarray screening to identify dwarf-specific lead miRNAs, and investigate their roles as pivotal molecular regulators directing the long-lived phenotype. Mapping the signature miRNAs to the inversely expressed putative target genes, followed by in situ immunohistochemical staining and in vitro correlation assays, reveals that dwarf mice post-transcriptionally regulate key proteins of intermediate metabolism, most importantly the biosynthetic pathway involving ornithine decarboxylase and spermidine synthase. Functional assays using 3'-untranslated region reporter constructs in co-transfection experiments confirm that miRNA-27a indeed suppresses the expression of both of these proteins, marking them as probable targets of this miRNA in vivo. Moreover, the putative repressed action of this miRNA on ornithine decarboxylase is identified in dwarf mouse liver as early as 2 months of age. Taken together, our results show that among the altered aspects of intermediate metabolism detected in the dwarf mouse liver--glutathione metabolism, the urea cycle and polyamine biosynthesis--miRNA-27a is a key post-transcriptional control. Furthermore, compared to its normal siblings, the dwarf mouse exhibits a head start in regulating these pathways to control their normality, which may ultimately contribute to its extended health-span and longevity.

Simulating the Current Water Cycle with the NASA Ames Mars Global Climate Model

Science.gov (United States)

Kahre, M. A.; Haberle, R. M.; Hollingsworth, J. L.; Brecht, A. S.; Urata, R. A.; Montmessin, F.

2017-12-01

The water cycle is a critical component of the current Mars climate system, and it is now widely recognized that water ice clouds significantly affect the nature of the simulated water cycle. Two processes are key to implementing clouds in a Mars global climate model (GCM): the microphysical processes of formation and dissipation, and their radiative effects on atmospheric heating/cooling rates. Together, these processes alter the thermal structure, change the atmospheric dynamics, and regulate inter-hemispheric transport. We have made considerable progress using the NASA Ames Mars GCM to simulate the current-day water cycle with radiatively active clouds. Cloud fields from our baseline simulation are in generally good agreement with observations. The predicted seasonal extent and peak IR optical depths are consistent MGS/TES observations. Additionally, the thermal response to the clouds in the aphelion cloud belt (ACB) is generally consistent with observations and other climate model predictions. Notably, there is a distinct gap in the predicted clouds over the North Residual Cap (NRC) during local summer, but the clouds reappear in this simulation over the NRC earlier than the observations indicate. Polar clouds are predicted near the seasonal CO2 ice caps, but the column thicknesses of these clouds are generally too thick compared to observations. Our baseline simulation is dry compared to MGS/TES-observed water vapor abundances, particularly in the tropics and subtropics. These areas of disagreement appear to be a consistent with other current water cycle GCMs. Future avenues of investigation will target improving our understanding of what controls the vertical extent of clouds and the apparent seasonal evolution of cloud particle sizes within the ACB.

Multiyear Simulations of the Martian Water Cycle with the Ames General Circulation Model

Science.gov (United States)

Haberle, R. M.; Schaeffer, J. R.; Nelli, S. M.; Murphy, J. R.

2003-01-01

Mars atmosphere is carbon dioxide dominated with non-negligible amounts of water vapor and suspended dust particles. The atmospheric dust plays an important role in the heating and cooling of the planet through absorption and emission of radiation. Small dust particles can potentially be carried to great altitudes and affect the temperatures there. Water vapor condensing onto the dust grains can affect the radiative properties of both, as well as their vertical extent. The condensation of water onto a dust grain will change the grain s fall speed and diminish the possibility of dust obtaining high altitudes. In this capacity, water becomes a controlling agent with regard to the vertical distribution of dust. Similarly, the atmosphere s water vapor holding capacity is affected by the amount of dust in the atmosphere. Dust is an excellent green house catalyst; it raises the temperature of the atmosphere, and thus, its water vapor holding capacity. There is, therefore, a potentially significant interplay between the Martian dust and water cycles. Previous research done using global, 3-D computer modeling to better understand the Martian atmosphere treat the dust and the water cycles as two separate and independent processes. The existing Ames numerical model will be employed to simulate the relationship between the Martian dust and water cycles by actually coupling the two cycles. Water will condense onto the dust, allowing the particle's radiative characteristics, fall speeds, and as a result, their vertical distribution to change. Data obtained from the Viking, Mars Pathfinder, and especially the Mars Global Surveyor missions will be used to determine the accuracy of the model results.

Moodne aeg : Moeuudised

Index Scriptorium Estoniae

2000-01-01

Moes on puhvseelik, mis moekriitik Amanda Harlech'i arvates teeb naise keha inetuks. Londonis elava prantslanna Emma Cassid'i cool'id ridikülid. Sian Evansi toidukäruga sõrmused. Graafik James Jarvise disainitud Briti firma Silas'i Evil Martini nimeline kummilelu ning tema sõber kummikass Bubba the Car.

Актер Суханов создает аритмию дел / Ксения Репсон

Index Scriptorium Estoniae

Репсон, Ксения

2011-01-01

Festivali Kuldne mask Eestis raames etendub Gerard Sibleyrasi absurdikomöödia "Ветер шумит в тополях" (Moskva Jevgeni Vahtangovi nim. Teater), lavastaja Rimas Tuminas. Lavastuses teeb kaasa Venemaa tuntud teatri- ja filminäitleja Maksim Suhhanov

Множественные "я" Максима Суханова / Максим Суханов ; интервьюировал Николай Караев

Index Scriptorium Estoniae

Суханов, Максим, 1963-

2011-01-01

Festivali Kuldne mask Eestis raames etendub Gerard Sibleyrasi absurdikomöödia "Ветер шумит в тополях" (Moskva Jevgeni Vahtangovi nim. Teater), lavastaja Rimas Tuminas. Lavastuses teeb kaasa Venemaa tuntud teatri- ja filminäitleja Maksim Suhhanov

Pressure distribution data from tests of 2.29 M (7.5 feet) span EET high-lift transport aircraft model in the Ames 12-foot pressure tunnel

Science.gov (United States)

Kjelgaard, S. O.; Morgan, H. L., Jr.

1983-01-01

A high-lift transport aircraft model equipped with full-span leading-edge slat and part-span double-slotted trailing-edge flap was tested in the Ames 12-ft pressure tunnel to determine the low-speed performance characteristics of a representative high-aspect-ratio supercritical wing. These tests were performed in support of the Energy Efficient Transport (EET) program which is one element of the Aircraft Energy Efficiency (ACEE) project. Static longitudinal forces and moments and chordwise pressure distributions at three spanwise stations were measured for cruise, climb, two take-off flap, and two landing flap wing configurations. The tabulated and plotted pressure distribution data is presented without analysis or discussion.

The NASA Ames PAH IR Spectroscopic Database: Computational Version 3.00 with Updated Content and the Introduction of Multiple Scaling Factors

Science.gov (United States)

Bauschlicher, Charles W., Jr.; Ricca, A.; Boersma, C.; Allamandola, L. J.

2018-02-01

Version 3.00 of the library of computed spectra in the NASA Ames PAH IR Spectroscopic Database (PAHdb) is described. Version 3.00 introduces the use of multiple scale factors, instead of the single scaling factor used previously, to align the theoretical harmonic frequencies with the experimental fundamentals. The use of multiple scale factors permits the use of a variety of basis sets; this allows new PAH species to be included in the database, such as those containing oxygen, and yields an improved treatment of strained species and those containing nitrogen. In addition, the computed spectra of 2439 new PAH species have been added. The impact of these changes on the analysis of an astronomical spectrum through database-fitting is considered and compared with a fit using Version 2.00 of the library of computed spectra. Finally, astronomical constraints are defined for the PAH spectral libraries in PAHdb.

Mereõhk teeb vabaks / Veronika Valk

Index Scriptorium Estoniae

Valk, Veronika, 1976-

2005-01-01

Tallinna sadamaalale eri arhitektuurivõistlustel pakutud linnaehituslikele ideedele keskenduv näitus "Back to the Sea" Tallinnas Lootsi tänav 13. Autori fantaasia Tallinna rannala tulevikust. Võrdluseks Barcelona, Helsingborg ja Tel Aviv

Tõde teeb meid vabaks / Tunne Kelam

Index Scriptorium Estoniae

Kelam, Tunne, 1936-

2007-01-01

Ilmunud ka: Harjumaa, 17. aug. 2007, lk. 2; Nädaline, 18. aug. 2007, lk. 11; Sakala, 22. aug. 2007, lk. 2; Sõnumitooja, 22. aug. 2007, lk. 6; Virumaa Teataja, 22. aug. 2007, lk. 11; Lääne Elu, 23. aug. 2007, lk. 2; Valgamaalane, 23. aug. 2007, lk. 2; Oma Saar, 23. aug. 2007, lk. 5; Põhjarannik, 23. aug. 2007, lk. 4; Järva Teataja, 23. aug. 2007, lk. 2; Võrumaa Teataja, 23. aug. 2007, lk. 2; Maaleht, 30. aug. 2007, lk. 7. Autor meenutab Hirvepargi meeleavaldust 23. augustil 1987

Jaapanlastele teeb muret stress / Harli Uljas

Index Scriptorium Estoniae

Uljas, Harli

2002-01-01

Jaapani tervishoiuministeeriumi andmetel oli möödunud aastal 143 karoshi juhtumit - kõrgeim tase alates 1987. aastast, mil probleemi esimest korda teadvustati. Karoshi - äkksurm ületöötamise tõttu

Miks Soome teistmoodi teeb? / Matti Maasikas

Index Scriptorium Estoniae

Maasikas, Matti, 1967-

2004-01-01

Soome vastuseisust NATO-ga liitumisele, selle ajaloolisest põhjustest, Soome kaitseministeeriumi raportist riigi sõjalisse liitu astumise mõjudest riigikaitsele. Avalik arvamus NATO-ga liitumise küsimusest. Vt. samas julgeolekuanalüütiku Max Jakobsoni vastust küsimusele Soome avaliku arvamuse vastuseisu kohta NATO-ga ühinemisele

Miks ta nii teeb? / Kristiina Voolaid

Index Scriptorium Estoniae

Voolaid, Kristiina

1999-01-01

Kuidas mõtleb ruumikujundaja, kui ta valib vorme, värve, materjale ja esemeid? Sisearhitekt Kristiina Voolaid seletab oma mõtteid Kawe Plaza hoones asuvate Hüvitusfondi ja Werol Tehased kontorite ning noorele perekonnale sisustatud vanalinnakorteri näitel

Netiajastu teeb autokraadid leidlikuks / Kalmo Hent

Index Scriptorium Estoniae

Kalmo, Hent, 1979-

2010-01-01

Riiklike huvide kaitsmiseks ja saavutamiseks on nii Hiina kui Venemaa asunud internetis looma oma inforuumi ning kehtestama internetitsensuuri, mis võimaldab mõjutada ja kontrollida sündmuste kajastamist

Mis teeb taimest ravimtaime? / Renata Sõukand

Index Scriptorium Estoniae

Sõukand, Renata, 1974-

2007-01-01

Sünteesides Ilmari Mannineni eesti rahvameditsiini kolmikjaotust Peirceѫi märgitüüpide kolmikjaotusega, järeldab autor, et 19. sajandi eesti taimravi toetub pigem taimega seotud kultuurilistele arusaamadele

Monica del Norte - Eesti maalikunstnik päikeselises Hispaanias / Anne-Mari Alver

Index Scriptorium Estoniae

Alver, Anne-Mari

2006-01-01

Deivi Oru alias Monica del Norte eneseleidmisest maalikunstniku, sisekujundaja ja kunstiõpetajana Hispaanias. Kunstnik teeb oma maalidele ise raamid. Koos abikaasa Alaniga on ta soetanud Räpina lähistele talukoha, millest tulevikus peaks saama näituste ja kunstilaagrite paik. 26. augustini on Monica del Norte maalid väljas Artdepoo galeriis

Que pasa? Mis toimub? / Veronika Valk

Index Scriptorium Estoniae

Valk, Veronika, 1976-

2005-01-01

Ettepanek luua Tallinna sadama infopunkt endisesse politseimajja Admiraliteedi basseini ääres. I korrusel paikneks infosaal, II ja III korruse võiks kunstnikele, musikutele jne. välja rentida, nende kõrvale mahuksid galeriid. Tänase Tallinna moto ning mereäärse ala planeerimise kontseptsioon võiksa olla "mereõhk teeb vabaks"

Eestis võltsitakse kunsti / Pekka Erelt

Index Scriptorium Estoniae

Erelt, Pekka, 1965-

2000-01-01

25. X 1999 kunstiagentuuri Haus oksjonil Anne Luigele müüdud Elmar Kitse õlimaal "Tants" on tõenäoliselt võltsing. Maie Raitari, Mai Levini, Tiiu Talvistu, Saskia Kasemaa, Jüri Kuuskemaa, Silvia Jõgeveri, Valve Janovi arvamused. Maali värvide keemilise analüüsi teeb EKMi restauraator Alar Nurkse.

Some aspects of case teaching : how to improve the educational process / Manuela Tvaronaviciene

Index Scriptorium Estoniae

Tvaronaviciene, Manuela

2003-01-01

Kaanel ajak. ilmumisaeg 2002/2003. Autor tutvustab juhtumianalüüsi kui ärijuhtide koolitusel kasutatavat õppevahendit Harvard Business School'is, IESE Business School'is ja teistes sama tüüpi ülikoolides. Autor teeb ülevaate juhtumi valiku printsiipidest ja juhtumianalüüsi läbiviimise metodoloogiast ning etappidest. Skeem

Vene draamateatri maja avatakse mais endisaegses hiilguses / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2006-01-01

Vene draamateatri, endise esinduskino "Gloria Palace'i" rekonstrueerimisest ja juurdeehitusest. Saali rekonstrueerimistöid teeb OÜ Vana Tallinn koostöös KAR-Grupiga, juurdeehituse projekteeris arhitekt Ra Luhse büroost Luhse ja Tuhal. Läti arhitekti Fridrihs Skujinsi projekteeritud "Gloria Palace" valmis 1926. a. Kommentaar "Pealinna esinduskino mall võeti Riiast"

Rikas ja vaene / Vello Kutsar

Index Scriptorium Estoniae

Kutsar, Vello

2006-01-01

Autor teeb ülevaate kohalike omavalitsuste arvestuslikust tulust. Joonised: 1. Arvestuslik tulu elaniku kohta 2005. aastal; 2. Arvestuslik tulu elaniku kohta (kr.) ja selle kasv %-des; 3. 10 rikkamat omavalitsust (tuh. kr.). Tabelid: 1. Eesti omavalitsused arvestusliku tulu järgi; 2. Arvestuslik tulu maakonniti; 3. Arvestuslik tulu Pärnumaa omavalitsustes (tuh. kr.)

Mis teoksil, härrad saadikud? / Igor Gräzin

Index Scriptorium Estoniae

Gräzin, Igor, 1952-

2007-01-01

Parlamendiliige meenutab, et hetkel, kui Riigikogu oli valmis arutama riigile üliolulist küsimust Eesti merepiiri õigest kulgemisest, tõstatati parlamendis saadikute kuluhüvitiste teema. Igor Gräzin kinnitab, et Riigikogu teeb ka edaspidi neid otsuseid, mis ei otsi lühiajalist populaarsust, vaid seisavad Eesti riikluse ja vabaduse kaitsel

Gurtshenko spojot pro pjat minut 50 let spustja / Olga Saburova

Index Scriptorium Estoniae

Saburova, Olga

2006-01-01

Režissöör Eldar Rjazanov teeb oma vene kultusfilmi "Karnevaliöö" uut, 50 aastat hilisemasse aega, s.o. tänapäeva, toodud varianti "Karnevaliöö 2 ". Seda näidatakse Venemaa Esimesel Kanalil uusaastakavas. Lähemalt sellest, keda ja mida selles filmis näeb-kuuleb

Uudised : Linnamuusikud Euroraadios. Sumera ja Kremerata Baltica. Vox Clamantis kontserdireisil. Bachi konkurss Saksamaal / Priit Kuusk

Index Scriptorium Estoniae

Kuusk, Priit, 1938-

2001-01-01

Ans. Linnamuusikud esindab Eestit 29. apr. Euroraadios Põhja- ja Baltimaade muusika õhtul. Kremerata Baltica esines Itaalias ja Saksamaal Sumera teosega "Symphone". 22. apr.-1. maini teeb ans. Vox Clamantis kontsertreisi Prantsusmaale ja Portugali. 11.-21. apr. Saarbrückenis toimunud IV rahvusvahelisest J.S.Bachi klaverikonkursist, kus osales ka kaks eesti pianisti

Kuhu on Tiiger tänaseks jõudnud? / Enel Mägi

Index Scriptorium Estoniae

Mägi, Enel

2003-01-01

Autor teeb ülevaate Tiigrihüppe programmi raames saavutatust alates 1997. aastast ja edasist arengut takistavatest teguritest, mille tõttu Tiigrihüppe Pluss programm on hakanud venima. Diagrammid: õpilaste ja arvuti suhe maakonniti 2003. a. alguses; internetiühendused Eesti koolides 2003. a. alguses; arvutite paiknemine koolis 2002. a. lõpus

Juhan Parts tuleb Ida-Virumaale kuulama kohalike inimeste mõtteid / Juhan Parts ; interv. Sergei Stepanov

Index Scriptorium Estoniae

Parts, Juhan, 1966-

2003-01-01

Ilmunud ka: Severnoje Poberezhje 25. juuli lk. 5, Narvskaja Nedelja 26. juuli lk. 5. 1. ja 2. augustil teeb Eesti Vabariigi peaminister Juhan Parts visiidi Ida-Virumaale, et külastada ettevõtteid, omavalitsusi ja kohtuda inimestega. Peaminister räägib, milliste eesmärkide ja ootustega ta visiidile läheb

Metabolic adaptations to short-term every-other-day feeding in long-living Ames dwarf mice.

Science.gov (United States)

Brown-Borg, Holly M; Rakoczy, Sharlene

2013-09-01

Restrictive dietary interventions exert significant beneficial physiological effects in terms of aging and age-related disease in many species. Every other day feeding (EOD) has been utilized in aging research and shown to mimic many of the positive outcomes consequent with dietary restriction. This study employed long living Ames dwarf mice subjected to EOD feeding to examine the adaptations of the oxidative phosphorylation and antioxidative defense systems to this feeding regimen. Every other day feeding lowered liver glutathione (GSH) concentrations in dwarf and wild type (WT) mice but altered GSH biosynthesis and degradation in WT mice only. The activities of liver OXPHOS enzymes and corresponding proteins declined in WT mice fed EOD while in dwarf animals, the levels were maintained or increased with this feeding regimen. Antioxidative enzymes were differentially affected depending on the tissue, whether proliferative or post-mitotic. Gene expression of components of liver methionine metabolism remained elevated in dwarf mice when compared to WT mice as previously reported however, enzymes responsible for recycling homocysteine to methionine were elevated in both genotypes in response to EOD feeding. The data suggest that the differences in anabolic hormone levels likely affect the sensitivity of long living and control mice to this dietary regimen, with dwarf mice exhibiting fewer responses in comparison to WT mice. These results provide further evidence that dwarf mice may be better protected against metabolic and environmental perturbations which may in turn, contribute to their extended longevity. © 2013.

Quantitative assessment of the dose-response of alkylating agents in DNA repair proficient and deficient ames tester strains.

Science.gov (United States)

Tang, Leilei; Guérard, Melanie; Zeller, Andreas

2014-01-01

Mutagenic and clastogenic effects of some DNA damaging agents such as methyl methanesulfonate (MMS) and ethyl methanesulfonate (EMS) have been demonstrated to exhibit a nonlinear or even "thresholded" dose-response in vitro and in vivo. DNA repair seems to be mainly responsible for these thresholds. To this end, we assessed several mutagenic alkylators in the Ames test with four different strains of Salmonella typhimurium: the alkyl transferases proficient strain TA1535 (Ogt+/Ada+), as well as the alkyl transferases deficient strains YG7100 (Ogt+/Ada-), YG7104 (Ogt-/Ada+) and YG7108 (Ogt-/Ada-). The known genotoxins EMS, MMS, temozolomide (TMZ), ethylnitrosourea (ENU) and methylnitrosourea (MNU) were tested in as many as 22 concentration levels. Dose-response curves were statistically fitted by the PROAST benchmark dose model and the Lutz-Lutz "hockeystick" model. These dose-response curves suggest efficient DNA-repair for lesions inflicted by all agents in strain TA1535. In the absence of Ogt, Ada is predominantly repairing methylations but not ethylations. It is concluded that the capacity of alkyl-transferases to successfully repair DNA lesions up to certain dose levels contributes to genotoxicity thresholds. Copyright © 2013 Wiley Periodicals, Inc.

Measurement of isotopic cross sections of the fission fragments produced in 500 AMeV 208Pb + p reaction

International Nuclear Information System (INIS)

Fernandez-Dominguez, B.

2003-03-01

The aim of this work is the study of the fission fragments produced in the spallation reaction 208 Pb + p at 500 AMeV. The fission fragments from Z=23 up to Z=59 have been detected and identified by using the inverse kinematics technique with the high-resolution spectrometer FRS. The production cross sections and the recoil velocities of 430 nuclei have been measured. The measured data have been compared with previous data. The isotopic distributions show a high precision. However, the absolute value of the fission cross section is higher than expected. From the experimental data the characteristics of the average fissioning system have been reconstructed (Z fis , A fis , E* fis ). In addition, the number of post-fission neutrons emitted from the fission fragments, v post , has been determined by using a new method. The experimental data have been compared to the two-steps models describing the spallation reaction. The impact of the model parameters on the observables has been analysed and the reasons Leading to the observed differences between the codes are also presented. This analyse shows a good agreement with the INCL4+ABLA code. (author)

Prevalência de práticas educativas acerca do aleitamento materno exclusivo (AME em Cuiabá - MT

Directory of Open Access Journals (Sweden)

Luma Natalia Barbosa

2015-03-01

Full Text Available Objetivo: Descrever a prevalência das práticas educativas em saúde sobre o aleitamento materno exclusivo (AME no Município de Cuiabá - MT nos meses de julho a dezembro de 2012. Métodos: Trata-se de um estudo descritivo transversal, realizado junto a mulheres internadas em um hospital. A amostra foi composta por 306 mulheres no período pós-parto imediato. Os dados foram coletados por meio de um questionário semiestruturado. Resultados: Ter oito anos ou mais de estudo (RP = 1,77; ter renda até dois salários mínimos (RP = 1,22; ter planejado a gravidez (RP = 1,31; ter iniciado o atendimento no serviço de pré-natal no primeiro trimestre (RP = 1,65 e serem primíparas (RP = 1,21 são características que aparecem associadas com uma maior chance de receber orientações sobre aleitamento materno do que as demais mulheres. Conclusão: Faz-se necessário repensar mudanças dessas práticas, a fim de se realizar ações educativas que busquem efetivar transformações na relação profissional/usuário, visando o acolhimento das gestantes.

Control-value theory: using achievement emotions to improve understanding of motivation, learning, and performance in medical education: AMEE Guide No. 64.

Science.gov (United States)

Artino, Anthony R; Holmboe, Eric S; Durning, Steven J

2012-01-01

In this AMEE Guide, we consider the emergent theoretical and empirical work on human emotion and how this work can inform the theory, research, and practice of medical education. In the Guide, we define emotion, in general, and achievement emotions, more specifically. We describe one of the leading contemporary theories of achievement emotions, control-value theory (Pekrun 2006), and we distinguish between different types of achievement emotions, their proximal antecedents, and their consequences for motivation, learning, and performance. Next, we review the empirical support for control-value theory from non-medical fields and suggest several important implications for educational practice. In this section, we highlight the importance of designing learning environments that foster a high degree of control and value for students. Finally, we end with a discussion of the need for more research on achievement emotions in medical education, and we propose several key research questions we believe will facilitate our understanding of achievement emotions and their impact on important educational outcomes.

Kaire Kemp-Tishler: "Igatsen luua midagi kole-ilusat" / Gitte Hint

Index Scriptorium Estoniae

Hint, Gitte

2003-01-01

Kaire Kemp-Tishler (sünd. 1964) kodu sisekujunduse projekteerimisest, tasakaalust sisearhitektuuris, oma kodust. Kaire Kemp-Tishlerist, tema tehtud tööde loetelu. 1998. aastast teeb K. Kemp-Tishler koostööd Ea Andlaga, kellega koos asutas 2001. a. OÜ sisearhitektuuribüroo ArtAku. Ill.: K. Kemp-Tishleri värv. portree

Comparative genotoxicity testing of Rhine river sediment extracts using the comet assay with permanent fish cell lines (RTG-2 and RTL-W1) and the Ames test

Energy Technology Data Exchange (ETDEWEB)

Kosmehl, T.; Braunbeck, T.; Hollert, H. [Dept. of Zoology, Aquatic Ecology and Toxicology Section, Univ. of Heidelberg (Germany); Krebs, F.; Manz, W. [German Federal Inst. of Hydrology, Koblenz (Germany); Erdinger, L. [Dept. for Hygiene and Medical Microbiology, Inst. for Hygiene, Univ. of Heidelberg (Germany)

2004-07-01

Whilst at least in Germany assessment strategies on the basis of chemical analysis and acute toxicity data dominated the last decades, the development of more specific biological endpoints and biomarkers in ecotoxicology is required in order to arrive at a good ecological potential and good chemical status of surface waters in the European river basins until the year 2015, as required by the European Water Framework Directive. Since sediments have for long been known to function both as a sink and as a source of pollutants in aquatic systems, and since part of the particle-associated substances have frequently been demonstrated to cause mutagenic and carcinogenic effects in aquatic organisms, particularly in fish, there is, among other requirements, an urgent need to develop, standardize and implement integrated vertebrate-based test systems addressing genotoxicity into recent sediment investigation strategies. Thus, the present study was designed to compare the suitability of two commonly used test systems, the comet assay and the Ames test, for the evaluation of the ecotoxicological burden of surface and core sediment samples from the river Rhine. Methods (or main features). In order to determine the importance of inherent enzymatic activities, two permanent fish cell lines with different biotransformation capacities, RTL-W1 and RTG-2, were compared with respect to their capability of detecting genotoxic effects in 18 surface and core sediment samples from 9 locations along the river Rhine in the comet assay with and without exogenous bioactivation. For further comparison, as a prokaryotic mutagenicity assay, the Salmonella plate incorporation assay (Ames test) with the test strains TA98 and TA100 with and without exogenous metabolic activation was used. Results and discussion. Whereas all sediment extracts induced genotoxic effects in the comet assay with RTL-W1 cells, only 12 out of 18 sediment extracts revealed significant genotoxicity in the tests with the

Wind-tunnel investigation of a large-scale VTOL aircraft model with wing root and wing thrust augmentors. [Ames 40 by 80 foot wind tunnel

Science.gov (United States)

Aoyagi, K.; Aiken, T. N.

1979-01-01

Tests were conducted in the Ames 40 by 80 foot wind tunnel to determine the aerodynamic characteristics of a large-scale V/STOL aircraft model with thrust augmentors. The model had a double-delta wing of aspect ratio 1.65 with augmentors located in the wing root and the wing trailing edge. The supply air for the augmentor primary nozzles was provided by the YJ-97 turbojet engine. The airflow was apportioned approximately 74 percent to the wing root augmentor and 24 percent to wing augmentor. Results were obtained at several trailing-edge flap deflections with the nozzle jet-momentum coefficients ranging from 0 to 7.9. Three-component longitudinal data are presented with the agumentor operating with and without the horizontal tail. A limited amount of six component data are also presented.

Mutagenicity of Tween 80-solvated mild gasification products in the Ames salmonella microsomal assay system. [Quarterly report, October--December 1991

Energy Technology Data Exchange (ETDEWEB)

1992-01-13

The results of the Tween 80-solvated Ames testing of six mild gasification samples indicate significant mutagenic activity only in the composite materials (MG-119 and MG-120), previously suspected from the DMSO-solvated assays, which had shown some variable but ultimately insignificant mutagenic responses. The activity of these samples from the Tween 80-solvated assays was quite low when compared to either the positive controls or the SRC-II HD coal-liquefaction reference material. The class of mutagenic activity expressed by these samples solvated in Tween 80 was that of an indirect-acting, frameshift mutagen(s) since significant activity was found only on tester strain TA98 in the presence of the metabolic activation fraction (S9). Because DMSO and other solvents have been shown to affect the mutagenic activity of certain pure chemicals, the possibility of solvent/mutagen interactions in complex mixtures such as coal-derived liquids exists. Thus, the testing of the genotoxic activity of undefined, chemically complex compounds may require the use of at least two solvent systems to reduce the possibility of artifactual findings. 10 refs., 4 tabs.

Büroohoone kui elus mäng / Urmas Oja

Index Scriptorium Estoniae

Oja, Urmas, 1981-2012

2005-01-01

Arvutimämgust inspireeritud Martin Aunini projekteeritud büroohoonest Tetris Tallinnas Mustamäel Mustamäe tee 46. 2005. a. valminud hoone fassaadid teeb eriliseks lasuurvärvidega rohe-kollaseks värvitud betoon. Projekteerija: EA Reng. Konstruktor: IB Pike. Infograafika: Andres Rohtla. Kommenteerivad M. Aunin ja Värvistuudio Parem Sein juhataja Margus Pootsmaa

Bjuro kak igrushka / Urmas Oja

Index Scriptorium Estoniae

Oja, Urmas, 1981-2012

2005-01-01

Arvutimämgust inspireeritud Martin Aunini projekteeritud büroohoonest Tetris Tallinnas Mustamäel Mustamäe tee 46. 2005. a. valminud hoone fassaadid teeb eriliseks lasuurvärvidega rohe-kollaseks värvitud betoon. Projekteerija: EA Reng. Konstruktor: IB Pike. Infograafika: Andres Rohtla. Kommenteerivad M. Aunin ja Värvistuudio Parem Sein juhataja Margus Pootsmaa

Siim Nestor soovitab : uute eesti plaatide esitlusõhtud! Metro Luminal. Lu : K. Metsatöll / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2004-01-01

Rockansambli Metro Luminal plaadi "Reboot" esitlusest Tartu Sadamateatris 9. dets. ja Rock Café's Tallinnas 10. dets.(kaasa teeb DJ Sing). Popansambli Lu:k albumist "Raadiomaja valvelauas" ja ansambli 10. aastapäeva tähistamisest 10. dets. Tallinnas Kunstiakadeemia saalis. Ansambli Metsatöll albumi "Hiiekoda" esitlusest 11.dets. Rock Café's Tallinnas

Kui suudab Steve, suudab ka Apple / Tarvo Vaarmets

Index Scriptorium Estoniae

Vaarmets, Tarvo

2008-01-01

Ehkki Apple'i kolmanda kvartali kasum kasvas kolmandiku võrra ja oli oodatust kümnendiku jagu suurem, langes ettevõtte aktsia hind börsil. Investoreid teeb rahutuks nii ettevõtte juhi Steve Jobsi tervis kui ka Apple'i majandusprognoos neljandaks kvartaliks. Lisa: Analüütikud on aktsia suhtes üksmeelel. Diagramm: Aktsia hinnal taas suund alla

Andrus Ansipi-Edgar Savisaare õppekava / Peeter Kreitzberg

Index Scriptorium Estoniae

Kreitzberg, Peeter, 1948-2011

2005-01-01

Ilmunud ka: Virumaa Nädalaleht 7. oktoober lk. 5. Riigikogu liige on seisukohal, et valitsuse juht ei tohi olla ankurdatud võimaliku mineviku külge, mis teeb võimatuks eetilise hinnangu andmise oma kabinetiliikmete tegudele. Autor rõhutab, et Eesti poliitiline areng ei sõltu mitte niivõrd õigusest, kuivõrd õiglusest, aususest ja otsekohesusest

Bagatellid : maailm / Nele-Eva Steinfeld, Ivo Heinloo

Index Scriptorium Estoniae

Steinfeld, Nele-Eva

2010-01-01

Sõnumeid muusikamaailmast: Neeme Järvist saab Orchestre de la Suisse Romande kunstiline ja muusikaline juht. Selgusid ajakirja Gramophone auhinnad. Lahkus koloratuursopran Joan Sutherland. Šotimaal avastati Antonio Vivaldi kodunud kontsert. Arvatavalt Napoleonile kuulunud Stradivari viiul müüdi internetioksjonil kõrge hinnaga. Dave Holland teeb flamenkot. Panama kultuurisaadik Danilo Perez sai auhinna. Jazzmuusik kaebas Snoop Doggi kohtusse

Euroopa kauge peegel / Dominique Moisi

Index Scriptorium Estoniae

Moisi, Dominique

2007-01-01

Ilmunud ka: Postimees : na russkom jazõke 26. jaan. lk. 7. Arutledes Aasia regiooni probleemide üle ja tuues näiteid Hiinast teeb autor järelduse, et ASEAN-i riikides puuduv seaduse jõud on takistuseks panna Aasia ühiskonda Euroopa mudeli põhjal elama. Vt. samas: Märt Läänemets. Hiinaga tasub olla ettevaatlik

Arusaamatused eluasemelaenu intressi tulumaksusoodustusega / Hiie Õunpuu

Index Scriptorium Estoniae

Õunpuu, Hiie

2005-01-01

Eluasemelaenu intresside tulust mahaarvamise kohta. Lisatud: Kask, Evelyn. Maksusoodustuse mõte on toetada eluaseme soetamist, lk. 34 ; Lehis, Lasse. MTA teeb liiga suuri üldistusi, lk. 34. Vt. ka Maksumaksja 2005, nr 2, lk 21-24. - Vt. ka: http://www.maksumaksjad.ee/modules/smartsection/item.php?itemid=78 ; http://www.maksumaksjad.ee/modules/smartsection/item.php?itemid=79.

Tõsjatsha i odin stsenarii Iraklija Kvirikadze / Irakli Kvirikadze ; interv. Nikolai Karajev

Index Scriptorium Estoniae

Kvirikadze, Irakli

2008-01-01

Gruusia päritolu režissöör ja stsenarist viibis Tallinnas seoses Pavel Makarovi korraldatud heategevusliku kultuurifestivaliga "Persoonide plejaad 2008". Intervjuus räägib ta Tallinnast, oma filmidest. Festivalil näidati lõike tema viimasest filmist "Vihmameister" ("The Rainbowmaker"), kus teeb kaasa ka laulja Toomas Urb. Festivalist fotod lk. 28, 30

Prioritetõ i problemõ razvitija avtomobilnõhh dorog v Polshe = Priorities and problems in the development of motorways in Poland / Jana Pieriegud

Index Scriptorium Estoniae

Pieriegud, Jana

2004-01-01

Autor teeb ülevaate Poola teedemajanduse ja maanteede olukorrast, analüüsib Euroopa Liidu standarditele vastavate teede puudumise põhjuseid ja teede-ehituse riiklikku strateegiat 2013. aastani, mille eesmärgiks on ühinemine Euroopa transpordi võrgustikuga (Trans-European Transport Network) ning mille täitmine sõltub Euroopa Liidu struktuurifondide finantsabist. Diarammid. Kaart

Eurovisiooni vaheklipid tõid ETV-le Aumuna

Index Scriptorium Estoniae

2003-01-01

Mulluse Eurovisiooni lauluvõistluse Tallinna kontserdi vaheklipid said Eesti reklaamiauhindade Kuldmuna jagamisel Aumuna. Üks vaheklippidest "Saabastega kass", mille režissöörid on René Vilbre ja Meelis Arulepp, valiti maineka Annecy animafilmifestivali nominentide hulka. 2 klippi valiti Norras Fredrikstadis toimuva animafestivali programmi. Praegu teeb Rene Vilbre koos võttegrupiga Euroopa Liidu referendumi teemalisi klippe

Environmental Assessment for US Department of Energy support of an Iowa State University Linear Accelerator Facility at Ames, Iowa

Energy Technology Data Exchange (ETDEWEB)

1990-05-01

The proposed Department of Energy (DOE) action is financial and technical support of construction and initial operation of an agricultural commodity irradiator (principally for meat), employing a dual mode electron beam generator capable of producing x-rays, at the Iowa State University Linear Accelerator located at Ames, Iowa. The planned pilot commercial-scale facility would be used for the following activities: conducting irradiation research on agricultural commodities, principally meats; in the future, after the pilot phase, as schedules permit, possibly conducting research on other, non-edible materials; evaluating effects of irradiation on nutritional and sensory quality of agricultural products; demonstrating the efficiency of the process to control or eliminate pathogens, and/or to prolong the commodities' post-harvest shelf-life via control or elimination of bacteria, fungi, and/or insects; providing information to the public on the benefits, safety and risks of irradiated agricultural commodities; determining consumer acceptability of the irradiated products; providing data for use by regulatory agencies in developing protocols for various treatments of Iowa agricultural commodities; and training operators, maintenance and quality control technicians, scientists, engineers, and staff of regulatory agencies in agricultural commodity irradiation technology. 14 refs., 5 figs.

Simulation of Shuttle launch G forces and acoustic loads using the NASA Ames Research Center 20G centrifuge

Science.gov (United States)

Shaw, T. L.; Corliss, J. M.; Gundo, D. P.; Mulenburg, G. M.; Breit, G. A.; Griffith, J. B.

1994-01-01

The high cost and long times required to develop research packages for space flight can often be offset by using ground test techniques. This paper describes a space shuttle launch and reentry simulating using the NASA Ames Research Center's 20G centrifuge facility. The combined G-forces and acoustic environment during shuttle launch and landing were simulated to evaluate the effect on a payload of laboratory rates. The launch G force and acoustic profiles are matched to actual shuttle launch data to produce the required G-forces and acoustic spectrum in the centrifuge test cab where the rats were caged on a free-swinging platform. For reentry, only G force is simulated as the aero-acoustic noise is insignificant compared to that during launch. The shuttle G-force profiles of launch and landing are achieved by programming the centrifuge drive computer to continuously adjust centrifuge rotational speed to obtain the correct launch and landing G forces. The shuttle launch acoustic environment is simulated using a high-power, low-frequency audio system. Accelerometer data from STS-56 and microphone data from STS-1 through STS-5 are used as baselines for the simulations. This paper provides a description of the test setup and the results of the simulation with recommendations for follow-on simulations.

Report of the Interagency Optical Network Testbeds Workshop 2, NASA Ames Research Center, September 12-14, 2005

Science.gov (United States)

2005-01-01

The Optical Network Testbeds Workshop 2 (ONT2), held on September 12-14, 2005, was cosponsored by the Department of Energy Office of Science (DOE/SC) and the National Aeronautics and Space Administration (NASA), in cooperation with the Joint Engineering Team (JET) of the Federal Networking and Information Technology Research and Development (NITRD) Program's Large Scale Networking (LSN) Coordinating Group. The ONT2 workshop was a follow-on to an August 2004 Workshop on Optical Network Testbeds (ONT1). ONT1 recommended actions by the Federal agencies to assure timely development and implementation of optical networking technologies and infrastructure. Hosted by the NASA Ames Research Center in Mountain View, California, the ONT2 workshop brought together representatives of the U.S. advanced research and education (R&E) networks, regional optical networks (RONs), service providers, international networking organizations, and senior engineering and R&D managers from Federal agencies and national research laboratories. Its purpose was to develop a common vision of the optical network technologies, services, infrastructure, and organizations needed to enable widespread use of optical networks; recommend activities for transitioning the optical networking research community and its current infrastructure to leading-edge optical networks over the next three to five years; and present information enabling commercial network infrastructure providers to plan for and use leading-edge optical network services in that time frame.

Current Background Noise Sources and Levels in the NASA Ames 40- by 80-Foot Wind Tunnel: A Status Report

Science.gov (United States)

Allen, Christopher S.; Jaeger, Stephen; Soderman, Paul; Koga, Dennis (Technical Monitor)

1999-01-01

Background noise measurements were made of the acoustic environment in the National Full-Scale Aerodynamics Complex 40- by 80-Foot Wind Tunnel (40x80) at NASA Ames Research Center. The measurements were acquired subsequent to the 40x80 Aeroacoustic Modernization Project, which was undertaken to improve the anechoic characteristics of the 40x80's closed test section as well as reduce the levels of background noise in the facility. The resulting 40x80 anechoic environment was described by Soderman et. al., and the current paper describes the resulting 40x80 background noise, discusses the sources of the noise, and draws comparisons to previous 40x80 background noise levels measurements. At low wind speeds or low frequencies, the 40x80 background noise is dominated by the fan drive system. To obtain the lowest fan drive noise for a given tunnel condition, it is possible in the 40x80 to reduce the fans' rotational speed and adjust the fans' blade pitch, as described by Schmidtz et. al. This idea is not new, but has now been operationally implemented with modifications for increased power at low rotational speeds. At low to mid-frequencies and at higher wind speeds, the dominant noise mechanism was thought to be caused by the surface interface of the previous test section floor acoustic lining. In order to reduce this noise mechanism, the new test section floor lining was designed to resist the pumping of flow in and out of the space between the grating slats required to support heavy equipment. In addition, the lining/flow interface over the entire test section was designed to be smoother and quieter than the previous design. At high wind speeds or high frequencies, the dominant source of background noise in the 40x80 is believed to be caused by the response of the in-flow microphone probes (required by the nature of the closed test section) to the fluctuations in the freestream flow. The resulting background noise levels are also different for probes of various

Recent Progress in Planetary Laboratory Astrophysics achieved with NASA Ames' COSmIC Facility

Science.gov (United States)

Salama, Farid; Sciamma-O'Brien, Ella; Bejaoui, Salma

2016-10-01

We describe the characteristics and the capabilities of the laboratory facility, COSmIC, that was developed at NASA Ames to generate, process and analyze interstellar, circumstellar and planetary analogs in the laboratory [1]. COSmIC stands for "Cosmic Simulation Chamber" and is dedicated to the study of neutral and ionized molecules and nanoparticles under the low temperature and high vacuum conditions that are required to simulate various space environments such as planetary atmospheres. COSmIC integrates a variety of state-of-the-art instruments that allow forming, processing and monitoring simulated space conditions for planetary, circumstellar and interstellar materials in the laboratory. The COSmIC experimental setup is composed of a Pulsed Discharge Nozzle (PDN) expansion, that generates a plasma in the stream of a free supersonic jet expansion, coupled to two high-sensitivity, complementary in situ diagnostics: a Cavity Ring Down Spectroscopy (CRDS) and laser induced fluorescence (LIF) systems for photonic detection [2, 3], and a Reflectron Time-Of-Flight Mass Spectrometer (ReTOF-MS) for mass detection [4].Recent results obtained using COSmIC will be highlighted. In particular, the progress that has been achieved in an on-going study investigating the formation and the characterization of laboratory analogs of Titan's aerosols generated from gas-phase molecular precursors [5] will be presented. Plans for future laboratory experiments on planetary molecules and aerosols in the growing field of planetary laboratory astrophysics will also be addressed, as well as the implications of studies underway for astronomical observations.References: [1] Salama F., in Organic Matter in Space, IAU S251, Kwok & Sandford eds, CUP, S251, 4, 357 (2008).[2] Biennier L., Salama, F., Allamandola L., & Scherer J., J. Chem. Phys., 118, 7863 (2003)[3] Tan X, & Salama F., J. Chem. Phys. 122, 84318 (2005)[4] Ricketts C., Contreras C., Walker, R., Salama F., Int. J. Mass Spec, 300

Expression of DNA methyltransferases is influenced by growth hormone in the long-living Ames dwarf mouse in vivo and in vitro.

Science.gov (United States)

Armstrong, Vanessa L; Rakoczy, Sharlene; Rojanathammanee, Lalida; Brown-Borg, Holly M

2014-08-01

Methyltransferase expression and DNA methylation are linked to aging and age-related disease. We utilized 3-, 12-, and 24-month-old Ames dwarf and their wild-type siblings to examine the genotype and age-related differences in the expression of methyltransferase enzymes related to DNA methylation in the liver, glycine-N-methyltransferase and DNA methyltransferase (DNMT). We found that DNMT proteins and transcripts are differentially expressed in dwarf mice compared with wild-type siblings that can be attributed to age and/or genotype. However, DNMT1 protein expression is drastically reduced compared with wild-type controls at every age. DNMT3a protein levels coincide with differences observed in DNMT activity. Growth hormone appears to modulate expression of DNMT1 and 3a in dwarf liver tissue and primary hepatocytes. Therefore, growth hormone may contribute to age-related processes, DNA methylation, and, ultimately, longevity. © The Author 2013. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Poliitilise trikoovooru aasta / Andrus Villem

Index Scriptorium Estoniae

Villem, Andrus

2006-01-01

Autor teeb tagasivaate 2005. Eesti poliitikaelule. Ilmunud ka: Järva Teataja 10. jaan. lk. 2, Nädaline 10. jaan. lk. 2, Hiiu Leht 10. jaan. lk. 2, Sakala, Lääne Elu, Vooremaa, Koit 12. jaan. lk. 2,2,2,6, Meie Maa, Elva Postipoiss 14. jaan. lk. 2, Valgamaalane, Põhjarannik, Severnoje Poberezhje 17. jaan. lk. 2, Sõnumitooja 18. jaan. lk. 2.

Rõivatööstuse TOP 50 aastal 2005

Index Scriptorium Estoniae

2006-01-01

Vt. samas artiklid: Meelis Virkebau. Rõiva- ja tekstiilitööstuses puuduvad lihtsad lahendused; Euratex: traditsioonilise tööstuse maht üha väheneb; Ketlin Priilinn. Rõivatootja ja Baltika teeb tõhusaid edusamme ka jaekaupmehena; SG Balticum panustab vabadust hindavatele klientidele; Lenne paigutas maailma aktsiaturgudel edukalt raha. Tabel: Rõivatööstuse ettevõtete üld- ja finantsandmed

Kas nüüd ka sinu pisarad, Moskva? / Ants Juske

Index Scriptorium Estoniae

Juske, Ants, 1956-2016

1998-01-01

Moskva kunstielu. Kriitikutest-kuraatoritest - Viktor Misiano, Josif Bakstein, Georgi Nikitsh, Andrei Kovaljov -, kunstnikest - Oleg Kulik, Aleksandr Brener, Tanja Antoshina, Anatoli Osmõlovski, Ilja Kabakov -, Marat Gelmani galeriist, Josif Baksteini kureeritud näitusest "Medialisatsioonid" Stockholmis, kunstnikegrupist AES (Tatjana Arzamasova, Lev Jevzovitsh, Jevgeni Svjatski) ja Misiano grupist (koostööd teeb filosoof Vladimir Sorokin), osalemisvõimalustest rahvusvahelistel näitustel

Esseid / John Gray ; tõlk. Ann Must

Index Scriptorium Estoniae

Gray, John

2007-01-01

"Biotehnoloogia ja posthumaanne tulevik" Uute tehnoloogiatega kaasnevatest ohtudest. "Vaatemängude ühiskonnas tagasi" Staarikultuse ja meelelahutustööstuse mõjust poliitikale ja majandusele. "Uued ressursisõjad" Ideoloogiliste konfliktide asendumisest geopoliitilistega. "Ameerika sõda kurjuse vastu" Ameerika välispoliitika teeb ohtlikuks usk kurja kaotamise võimalikkusse. "Aruanne akadeemiale" Inimkonna laastavast mõjust keskkonnale, vajadusest rahvastikukontrolli järele

Laamendav vene nats, põlev lipp pihus / Toomas Kümmel

Index Scriptorium Estoniae

Kümmel, Toomas

2007-01-01

Autor leiab, et pronkssõduri dilemmas ei ole Eesti võimud suutnud esile tõsta peamist: see mälestusmärk sümboliseerib valedele rajatud müüti Teisest maailmasõjast. Keeruliseks teeb asja see, et osa erakondi seda müüti kaitseb. Vt. samas: Sõja põhivaled; Koondnimekiri võimalikest Tõnismäele maetud punaarmeelastest

Maksumaksjate liit ei toeta maksukoormuse tõusu / Lasse Lehis

Index Scriptorium Estoniae

Lehis, Lasse, 1972-

2009-01-01

Eesti Maksumaksjate Liidu seisukohtadest muudatuste tegemise kohta Eesti maksusüsteemis. Lisa: Maksumaksjate liit teeb ettepaneku vähendada maksuintressi määra (EML pressiteade 19. 01. 2009 ; Lehis, Lasse. Maksuvõla ajatamisel intressimääraks null ; Rahandusministri vastus seaduseelnõu algatamise ettepaneku kohta 9. 02. 2009). Vt. ka: http://www.maksumaksjad.ee/modules/smartsection/item.php?itemid=688.

Jaan Pillesaar : Eesti vajab revolutsiooni / Urmas Vaino

Index Scriptorium Estoniae

Vaino, Urmas, 1974-

2007-01-01

1991. aastal startinud Helmes on tarkvaratootjana jõudnud Eesti tugevamate tegijate hulka. Firma käive ületab 100 miljonit krooni ning 30 miljoni ulatuses läheb tarkvara ekspordiks. Helmese juht Jaan Pillesaar spetsialistide puudusest, arengu piduriks olevast maksusüsteemist, riigi suhtumisest teabeärisse. Lisad: Mida Helmes teeb?; Helmese säravad tütred: MarkIT ja Now! Innovations

Acoustic Modifications of the Ames 40x80 Foot Wind Tunnel and Test Techniques for High-Speed Research Model Testing

Science.gov (United States)

Soderman, Paul T.; Olson, Larry (Technical Monitor)

1995-01-01

The NFAC 40- by 80- Foot Wind Tunnel at Ames is being refurbished with a new, deep acoustic lining in the test section which will make the facility nearly anechoic over a large frequency range. The modification history, key elements, and schedule will be discussed. Design features and expected performance gains will be described. Background noise reductions will be summarized. Improvements in aeroacoustic research techniques have been developed and used recently at NFAC on several wind tunnel tests of High Speed Research models. Research on quiet inflow microphones and struts will be described. The Acoustic Survey Apparatus in the 40x80 will be illustrated. A special intensity probe was tested for source localization. Multi-channel, high speed digital data acquisition is now used for acoustics. And most important, phased microphone arrays have been developed and tested which have proven to be very powerful for source identification and increased signal-to-noise ratio. Use of these tools for the HEAT model will be illustrated. In addition, an acoustically absorbent symmetry plane was built to satisfy the HEAT semispan aerodynamic and acoustic requirements. Acoustic performance of that symmetry plane will be shown.

Building bridges between theory and practice in medical education using a design-based research approach: AMEE Guide No. 60.

Science.gov (United States)

Dolmans, Diana H J M; Tigelaar, D

2012-01-01

Medical education research has grown enormously over the past 20 years, but it does not sufficiently make use of theories, according to influential leaders and researchers in this field. In this AMEE Guide, it is argued that design-based research (DBR) studies should be conducted much more in medical education design research because these studies both advance the testing and refinement of theories and advance educational practice. In this Guide, the essential characteristics of DBR as well as how DBR differs from other approach such as formative evaluation are explained. It is also explained what the pitfalls and challenges of DBR are. The main challenges deal with how to insure that DBR studies reveal findings that are of a broader relevance than the local situation and how to insure that DBR contributes toward theory testing and refinement. An example of a series of DBR studies on the design of a teaching portfolio in higher education that is aimed at stimulating a teacher's professional development is described, to illustrate how DBR studies actually work in practice. Finally, it is argued that DBR-studies could play an important role in the advancement of theory and practice in the two broad domains of designing or redesigning work-based learning environments and assessment programs.

Analysis and characterization of heavy residues produced in 129Xe + natSn reactions between 8 and 25 AMeV

International Nuclear Information System (INIS)

Moisan, J.

2008-06-01

Studies with the INDRA multidetector of the 129 Xe + nat Sn reactions showed the unexpected existence of heavy fragments with a charge as large as Z=70. The charges of Xe and Sn are 54 and 50 respectively. Reactions between nuclei with a charge product greater than 2700 are dominated by deep inelastic collisions. For Xe + Sn the product is exactly 2700. After these observations, 129 Xe + nat Sn reactions at 8, 12, 15, 20 and 25 AMeV have been done. It will then be possible to clarify if the heavy residues are formed by an incomplete fusion, massive transfers occurring in deep inelastic collisions or a very asymmetric fission of a compound system. This work will present experimental results obtained by the analysis of these experiments. We will show that heavy residues are formed with a production cross-section of 10 -2 mb. Angular distributions show that the residues can be produced by an incomplete fusion of the projectile and the target. The study of the products in coincidence with the residues shows that a compound system was formed, followed by a fission producing the residue and a lighter fragment. The comparison with a phenomenological model, HIPSE, confirms that the model is valid at these energies

Evaluation of Different Methods for Identification of Structural Alerts Using Chemical Ames Mutagenicity Data Set as a Benchmark.

Science.gov (United States)

Yang, Hongbin; Li, Jie; Wu, Zengrui; Li, Weihua; Liu, Guixia; Tang, Yun

2017-06-19

Identification of structural alerts for toxicity is useful in drug discovery and other fields such as environmental protection. With structural alerts, researchers can quickly identify potential toxic compounds and learn how to modify them. Hence, it is important to determine structural alerts from a large number of compounds quickly and accurately. There are already many methods reported for identification of structural alerts. However, how to evaluate those methods is a problem. In this paper, we tried to evaluate four of the methods for monosubstructure identification with three indices including accuracy rate, coverage rate, and information gain to compare their advantages and disadvantages. The Kazius' Ames mutagenicity data set was used as the benchmark, and the four methods were MoSS (graph-based), SARpy (fragment-based), and two fingerprint-based methods including Bioalerts and the fingerprint (FP) method we previously used. The results showed that Bioalerts and FP could detect key substructures with high accuracy and coverage rates because they allowed unclosed rings and wildcard atom or bond types. However, they also resulted in redundancy so that their predictive performance was not as good as that of SARpy. SARpy was competitive in predictive performance in both training set and external validation set. These results might be helpful for users to select appropriate methods and further development of methods for identification of structural alerts.

Tallinn teeb konkursi eel Kopli liinidele planeeringu

Index Scriptorium Estoniae

2008-01-01

Tallinna linnavalitsus valmistab ette uut konkurssi Kopli liinide hoonestaja leidmiseks. Esmalt võtab linn vastu detailplaneeringu, mille alusel sõnastab hoonestusõiguse tingimused. Esimese konkursi võitnud Primos Kinnisvara ei saavutanud linnaga üksmeelt hoonestusõiguse lepingu tingimuste suhtes

Presidendi poeg: armee teeb meheks! / Karoliina Vasli

Index Scriptorium Estoniae

Vasli, Karoliina

2009-01-01

President Toomas Hendrik Ilvese poeg Luukas Kristjan Ilves andis 11. septembril 2009 Tapal Kirde kaitseringkonna väeosas sõdurivande. Juuresoleval fotol riigipea oma poega õnnitlemas. Vt. ka juhtkiri lk. 8: Vahva sõdur Ilves

Jutta Rabe teeb Estonia hukust uue filmi

Index Scriptorium Estoniae

2002-01-01

Eile alustas Saksa ajakirjanik Jutta Rabe oma filmi "Baltic Storm" võtetega, mis kujutab parvlaev "Estonia" hukku venelaste vandenõu tulemusena. Peale Rabe on stsenaristid veel saksa advokaat Henning Witte ja rootslane Kaj Holmberg

Võlurpoiss Potter teeb ekraanidel imetrikke / Neeme Raud

Index Scriptorium Estoniae

Raud, Neeme, 1969-

2001-01-01

Joanne Rowling'u lasteraamatu "Harry Potter ja Tarkade kivi" ekraniseering "Harry Potter and the Philosopher's Stone" esimese kolme linastuspäeva kassatulu USAs ja Kanadas purustas kõik rekordid. Ka kassafilmide esikümne nimekiri

Läti film teeb kadedaks / Mart Rummo

Index Scriptorium Estoniae

Rummo, Mart

2001-01-01

Kinomajas Läti filmipäevadel näidatud filmidest. Pikemalt Romualds Piparsi dokumentaalfilmist "Elu vabadusele" ning režissööri lühimängufilmist "Pulm". Autor küsib ka Läti Riikliku Filmikeskuse direktorilt Bruno Asèuksilt läti täispika mängufilmi "Ohtlik suvi" menu saladust kodumaal

"Tulnukas" teeb jõmmist kunstiteose / Keiu Virro

Index Scriptorium Estoniae

Virro, Keiu

2007-01-01

Tallinna Ülikooli filmi ja video õppetoolis Rasmus Merivoo lõputööna valminud filmist "Tulnukas ehk Valdise päästmine 11 osas", mis kogub internetis vaatajaid ning on muutumas kultusfilmiks. 22-minutiline lühifilm portreteerib Eestis laialt levinud subkultuuri - jõmlust ja rullnoklust

Internet lekib / Ando Urbas

Index Scriptorium Estoniae

Urbas, Ando, 1978-

2005-01-01

Seni Eesti suurima wardrivingu käigus avastati Tallinnast üle 2000 WiFi-leviala, mis teeb nende hinnanguliseks koguarvuks ligi 10 000. Sageli asuvad WiFi-seadmed nii tihedalt koos, et need segavad üksteise tööd ja iga kolmas võrk Tallinnas on kõigile vabalt (kuri)tarvitatav. Lisa: Kuidas leida vaba kanalit? WiFi-võrgu kaitsmine. Kes tegid?

Jäätmeturism tuleb peatada! / Aap Mumme

Index Scriptorium Estoniae

Mumme, Aap

2004-01-01

Tallinna uuele prügilale teeb muret vähene jäätmekogus, autori sõnul on selle põhjustanud jäätmeturism: märkimisväärne kogus Tallinnas ja selle lähiümbruses tekkivatest jäätmetest veetakse keskkonnanõuetele mittevastavatesse väikeprügilatesse. Autori arvates peaks kehtestama keskkonnanõuetele vastavatele prügilatele kindlad teeninduspiirkonnad

Korter Helsingi kohal / Suvi Ruotsi

Index Scriptorium Estoniae

Ruotsi, Suvi

2008-01-01

Soome disaineri Tanja Sipilä perekonna korter (71, 5 m2) Helsingi kesklinnas 20. sajandi algul ehitatud kivimajas. Korter on suures osas sisustatud modernse disainmööbliga. T. Sipila kujundab esemeid, mööblit ning teeb sisekujundusi koos Susanna Hoikkalaga, kellega koos asutasid firma Design Machine. Vt. ka lk. 48: Meister, Lylian. Valge kodu stiilsed aktsendid - valik esemeid Eestist kodu sisustamiseks samas võtmes

Estonia hukk jõuab Eesti kinodesse sügisel / Tiit Tuumalu

Index Scriptorium Estoniae

Tuumalu, Tiit, 1971-

2003-01-01

Saksamaal peatselt esilinastuv poliitiline põnevusfilm "Balti torm" ("Baltic Storm"), mis kujutab parvlaev "Estonia" hukku venelaste vandenõu tulemusena, jõuab Eestis siinse levitaja Mati Seppingu sõnul linale novembri alul. Produtsendid on Jutta Rabe ja Kaj Holmberg, peaosades Greta Scacchi ja Jürgen Prochnow. Kaasa teeb ka Donald Sutherland USA kindrali rollis. Eesti näitlejaist on kapten Arvo Kallase rollis Rein Oja

Viking GCMS Data Restoral and Perceiving Temperature on Other Worlds: Astrobiology Projects at NASA Ames

Science.gov (United States)

Guzman, Melissa

2015-01-01

The primary task for the summer was to procure the GCMS data from the National Space Science Data Coordinated Archive (NSSDCA) and to assess the current state of the data set for possible reanalysis opportunities. After procurement of the Viking GCMS data set and analysis of its current state, the internship focus shifted to preparing a plan for restoral and archiving of the GCMS data set. A proposal was prepared and submitted to NASA Headquarters to restore and make available the 8000 mass chromatographs that are the basic data generated by the Viking GCMS instrument. The relevance of this restoral and the methodology we propose for restoral is presented. The secondary task for the summer is to develop a thermal model for the perceived temperature of a human standing on Mars, Titan, or Europa. Traditionally, an equation called "Fanger's comfort equation" is used to measure the perceived temperature by a human in a given reference environment. However, there are limitations to this model when applied to other planets. Therefore, the approach for this project has been to derive energy balance equations from first principles and then develop a methodology for correlating "comfort" to energy balance. Using the -20 C walk-in freezer in the Space Sciences building at NASA Ames, energy loss of a human subject is measured. Energy loss for a human being on Mars, Titan and Europa are calculated from first principles. These calculations are compared to the freezer measurements, e.g. for 1 minute on Titan, a human loses as much energy as x minutes in a -20 C freezer. This gives a numerical comparison between the environments. These energy calculations are used to consider the physiological comfort of a human based on the calculated energy losses.

Caracterización molecular de Colletotrichum gloeosporioides aislado de plantas de ñame de la Costa Atlántica Colombiana utilizando la técnica “DNA Amplification Fingerprinting (DAF”

Directory of Open Access Journals (Sweden)

Natalia Giraldo Marroquín

2016-01-01

Full Text Available La antracnosis en ñame, causada por el hongo Colletotrichum gloeosporioides, es una enfermedad relevante que posee el potencial de destruir el 100% de la cosecha, convirtiéndose en la principal limitante fitosanitaria para el rendimiento del cultivo en el país. Esta es una situación preocupante considerando que aproximadamente 35.000 familias de pequeños y medianos agricultores de la Costa Atlántica Colombiana subsisten de este cultivo; es por esto que el objetivo de este trabajo fue caracterizar molecularmente 42 aislamientos del hongo procedentes de plantas de ñame con síntomas de la enfermedad, utilizando la técnica molecular “DNA Amplification Fingerprinting (DAF”, caracterizada por su resolución en la determinación de la variabilidad genética de diferentes organismos. Para la determinación de polimorfismos, se amplificaron 16 marcadores DAF implementando iniciadores tipo decámero, los cuales fueron visualizados por electroforesis en microchip con el equipo MCE-202 MultiNA. Se evaluó la reproducibilidad de la técnica DAF. La amplificación arrojó 391 bandas inequívocamente polimórficas en todas las muestras, el coeficiente de Dice identificó cinco grupos con 0.30% de similaridad y el índice de diversidad genética fue de 0.28; datos que reflejan un alto grado de variabilidad en la colección estudiada de C. gloeosporioides. Ésta puede deberse, al intercambio de germoplasma, a su condición heterotálica, a las mutaciones y al alto potencial de dispersión de las conidias que le permiten mantener la viabilidad bajo condiciones adversas. Por último, se encontró que DAF es una técnica reproducible, confirmando que es una metodología fiable para la caracterización molecular de hongos.

A Tale of Two Small Business Grants: The Best of Times, the Worst of Times from the NASA Ames Small Business Innovative Research (SBIR) Program

Science.gov (United States)

Kojiro, Daniel R.; Lee, Geoffrey S.

2006-01-01

The purposes of the SBIR Program are to: stimulate technological innovation in the private sector; strengthen the role of Small Business Concerns (SBCs) in meeting Federal research and development needs; increase the commercial application of these research results; and encourage participation of socially and economically disadvantaged persons and women-owned small businesses. The process can be highly rewarding, providing the small business with resources to pursue research and development with a focus on providing NASA with new and advanced capabilities. We present two examples of how the NASA Ames SBIR Program has addressed these purposes, nurturing innovative ideas from small, businesses into commercially viable products that also address analytical needs in space research. These examples, from the Science Instruments for Conducting Solar System Exploration Subtopic, describe the journey from innovative concept to analytical instrument, one successful and one hampered by numerous roadblocks (including some international intrigue}.

The role of the Joint Research Centre from the European Commission in the European Structural Integrity Networks AMES, ENIQ and NESC

International Nuclear Information System (INIS)

Estorff, U. von; Torronen, K.

1999-01-01

Due to the reduction in many countries of the research budget for nuclear safety several European institutions and organisations and the Institute for Advanced Materials (IAM) of the Joint Research Centre (JRC) of the European Commission (EC) have developed co-operative programmes now organised into 'Networks' for mutual benefit. They include utilities, engineering companies, research and development (R and D) laboratories and regulatory bodies. These Networks are all organised and managed in a similar way, i.e. like the successful Programme for the Inspection of Steel Components (PISC). The IAM plays the role of Operating Agent, Reference Laboratory and Network Manager of these Networks: European Network on Ageing Materials Evaluation and Studies (AMES), European Network for Inspection Qualification (ENIQ) and Network for Evaluating Steel Components (NESC), each of them dealing with a specific aspect of fitness for purpose of materials in structural components. This article will describe how the network organisation works, which was the positive experience from the past, why the networks are a tool for integrating fragmented research in Europe and how they fit into the mission of the JRC and therefore follow the EC policy. (orig.)

Growth hormone abolishes beneficial effects of calorie restriction in long-lived Ames dwarf mice.

Science.gov (United States)

Gesing, Adam; Al-Regaiey, Khalid A; Bartke, Andrzej; Masternak, Michal M

2014-10-01

Disruption of the growth hormone (GH) axis promotes longevity and delays aging. In contrast, GH over-expression may lead to accelerated aging and shorter life. Calorie restriction (CR) improves insulin sensitivity and may extend lifespan. Long-lived Ames dwarf (df/df) mice have additional extension of longevity when subjected to 30% CR. The aim of the study was to assess effects of CR or GH replacement therapy separately and as a combined (CR+GH) treatment in GH-deficient df/df and normal mice, on selected metabolic parameters (e.g., insulin, glucose, cholesterol), insulin signaling components (e.g., insulin receptor [IR] β-subunit, phosphorylated form of IR [IR pY1158], protein kinase C ζ/λ [p-PKCζ/λ] and mTOR [p-mTOR]), transcription factor p-CREB, and components of the mitogen-activated protein kinase (MAPK) signaling (p-ERK1/2, p-p38), responsible for cell proliferation, differentiation and survival. CR decreased plasma levels of insulin, glucose, cholesterol and leptin, and increased hepatic IR β-subunit and IR pY1158 levels as well as IR, IRS-1 and GLUT-2 gene expression compared to ad libitum feeding, showing a significant beneficial diet intervention effect. Moreover, hepatic protein levels of p-PKCζ/λ, p-mTOR and p-p38 decreased, and p-CREB increased in CR mice. On the contrary, GH increased levels of glucose, cholesterol and leptin in plasma, and p-mTOR or p-p38 in livers, and decreased plasma adiponectin and hepatic IR β-subunit compared to saline treatment. There were no GH effects on adiponectin in N mice. Moreover, GH replacement therapy did not affect IR, IRS-1 and GLUT-2 gene expression. GH treatment abolishes the beneficial effects of CR; it may suggest an important role of GH-IGF1 axis in mediating the CR action. Suppressed somatotrophic signaling seems to predominate over GH replacement therapy in the context of the examined parameters and signaling pathways. Copyright © 2014 Elsevier Inc. All rights reserved.

Communication skills: an essential component of medical curricula. Part I: Assessment of clinical communication: AMEE Guide No. 51.

Science.gov (United States)

Laidlaw, Anita; Hart, Jo

2011-01-01

This AMEE Guide in Medical Education is Part 1 of a two part Guide covering the issues of Communication. This Guide has been written to provide guidance for those involved in planning the assessment of clinical communication and provides guidance and information relating to the assessment of various aspects of clinical communication; its underlying theory; its practical ability to show that an individual is competent and its relationship to students' daily performance. The advantages and disadvantages of assessing specific aspects of communication are also discussed. The Guide draws attention to the complexity of assessing the ability to communicate with patients and healthcare professionals, with issues of reliability and validity being highlighted for each aspect. Current debates within the area of clinical communication teaching are raised: when should the assessment of clinical communication occur in undergraduate medical education?; should clinical communication assessment be integrated with clinical skills assessment, or should the two be separate?; how important should the assessment of clinical communication be, and the question of possible failure of students if they are judged not competent in communication skills? It is the aim of the authors not only to provide a useful reference for those starting to develop their assessment processes, but also provide an opportunity for review and debate amongst those who already assess clinical communication within their curricula, and a resource for those who have a general interest in medical education who wish to learn more about communication skills assessment.

Isospin influence on the decay modes of the systems produced in the 78,86Kr +40,48Ca reactions at 10 AMeV

Directory of Open Access Journals (Sweden)

Gnoffo B.

2016-01-01

Full Text Available The results of the analysis of the reactions 78,86Kr +40,48 Ca at 10 AMeV are presented. The experiment was performed at the INFN Laboratori Nazionali del Sud (LNS in Catania by using the 4π multidetector CHIMERA, with beams delivered by the Superconductive Cyclotron. The competition among the various disintegration paths and in particular the isospin effects on the decay modes of the produced composite systems are investigated; this provides information about fundamental nuclear quantities such as level density, fission barrier and viscosity. Different isotopic composition and relative richness are observed among the reaction products of the two systems. An odd-even staggering effect is present in the charge distributions, in particular for the light fragments produced by the neutron-poor system. The kinematical characteristics of the IMF seem to indicate a high degree of the relaxation of the formed system. Besides, global features analysis seems to show some differences in the contribution arising from the various reaction mechanisms for the two reactions.

Taifuun nimega Valimised on möödas / Mait Klaassen

Index Scriptorium Estoniae

Klaassen, Mait, 1955-

2005-01-01

Ilmunud ka: Põhjarannik 20. okt., lk. 2, Severnoje Poberezhje 20. okt., lk. 2, Meie Maa 20. okt., lk. 2, Sakala 21. okt., lk. 2, Vali Uudised 21. okt. lk. 2, Koit, Järva Teataja 22. okt. lk. 6,2, Lääne Elu 25. okt., lk. 2, Harjumaa 25. okt. lk. 2, Vooremaa 27. okt. lk. 2. Parlamendisaadik, Reformierakonna liige Mait Klaassen teeb kokkuvõtte lõppenud kohalikest valimistest

Monetary ecosystem services valuation in natural environment management

OpenAIRE

Álvarez, David

2017-01-01

As it happened with Stern Report, which made international community change their attitude related to climate change, TEEB (The Economics of Ecosystem Services and Biodiversity) was a turning point in valuing biodiversity and ecosystem services. This change of attitude happened, partially, thanks to include monetary ecosystem valuation of ecosystem services and how much their conservation and avoid their loss worth to the entire society. Integrate monetary valuation in green infrastructur...

Vastutus Euroopa eest / Igor Gräzin

Index Scriptorium Estoniae

Gräzin, Igor, 1952-

2004-01-01

Ilmunud ka: Põhjarannik, 14. apr. 2004, lk. 2; Severnoje Poberezhje, 14. apr. 2004, lk. 2; Valgamaalane, 13. apr. 2004, lk. 2; Sakala, 13. apr. 2004, lk. 2; Hiiu Leht, 16. apr. 2004, lk. 2; Paremad Uudised, apr., nr. 4, 2004, lk. 7; Meie Maa, 22. apr. 2004, lk. 2; Harjumaa, 23. apr. 2004, lk. 2. Autor teeb kokkuvõtteid Eesti majanduse ja poliitilise struktuuri edukusest ning vaeb EL-ist tulevaid ebameeldivusi

Sladkaja zhizn oboidjotsja nam dorogo / Jekaterina Rodina

Index Scriptorium Estoniae

Rodina, Jekaterina

2006-01-01

Kui pärast Nõukogude Liidu lagunemist oldi mures ajude äravoolu pärast, siis praegu teeb muret töökäte lahkumine ja kvalifitseeritud spetsialistide puudus. Mitteametlikel andmetel töötavad ligi 30 000 Eesti elanikku välisriikides. Töökäte puudus on kaasa toonud kiire palgatõusu, millega omakorda kaasneb tarbimise kasv. Välistööjõud Eesti turul

Respuesta fisiológica del ñame espino (Dioscorea Rotundata Poir a las densidades de siembra

Directory of Open Access Journals (Sweden)

Dairo J. Pérez

2015-12-01

Full Text Available Esta investigación tuvo como objetivo estudiar la respuesta fisiológica del ñame espino (Dioscorea rotundata cv. brasilero en función del incremento de las densidades de siembra, bajo la oferta ambiental del Sinú medio. El estudio se llevó a cabo en la Universidad de Córdoba (Montería, Colombia, donde se evaluaron las densidades de siembra de 45.455, 30.303, 22.727 y 10.101 plantas/ha; bajo un diseño de Bloques Completos al Azar con tres repeticiones. Las variables de respuestas consideradas fueron la fotosíntesis neta (Pn, medida en tres etapas fenológicas (vegetativa, inicio y final de tuberización; y los índices de crecimiento: tasa absoluta de crecimiento (TAC, tasa de asimilación neta (TAN, tasa relativa de crecimiento (TRC e índice de área foliar (IAF. La Pn no varió entre las densidades de siembra (p≤0,05, pero después de la etapa vegetativa, se redujo en promedio un 19,14% para el inicio y final de la tuberización. La TAC y la TRC tuvieron similar tendencia, se incrementaron desde la etapa vegetativa, pero esta última se redujo al final del cultivo. La TAN comenzó a decrecer desde la etapa vegetativa con un leve incremento al final del ciclo. El IAF se incrementó significativamente a partir de la tuberización, para las densidades de siembra superiores a 10.101 plantas/ha, alcanzando valores entre 3,08 y 4,03. Se concluye que los índices de crecimiento a excepción del IAF y la Pn, no variaron entre las densidades de siembra, probablemente por la capacidad de la especie de regular su actividad fisiológica en función de la densidad de siembra.

Extreme testing of undiluted e-cigarette aerosol in vitro using an Ames air-agar-interface technique.

Science.gov (United States)

Thorne, D; Hollings, M; Seymour, A; Adamson, J; Dalrymple, A; Ballantyne, M; Gaca, M

2018-04-01

There is a growing consensus that e-cigarettes hold the potential for reducing the harm associated with cigarette smoking. Recently published studies have reported in vitro testing of e-cigarettes, demonstrating reduced toxicological and biological effects. Few studies however have reported the use of e-cigarettes under extreme testing conditions. To assess the full mutagenic potential of a commercially available electronic-cigarette (Vype ePen), this study investigated the delivery of aerosol under extreme conditions, using a scaled-down 35 mm plate Ames bacterial reverse mutagenicity assay. S. typhimurium strains TA98, TA100, TA97, TA104 and E. coli WP2 uvrA pKM101 with or without metabolic activation (S9), were employed. Using a modified Vitrocell VC 10 exposure system 0, 180, 360, 540, 720 or 900 puffs of undiluted e-cigarette aerosol was generated and delivered to bacterial cultures aligned to reported human consumption data. The results demonstrate that no mutagenic activity was observed in any strain under any test condition even when exposed to 900 puffs of undiluted e-cigarette aerosols +/- S9. Positive control responses were observed in all strains +/- S9. Nicotine assessments demonstrated an increased and consistent aerosol delivery, with calculated maximum doses of ∼1 mg/mL delivery of nicotine. These data demonstrate the validity of this unique testing approach and adds further information to the growing weight of evidence that e-cigarettes offer substantially reduced exposure when compared to conventional cigarette smoke. For future in vitro assessments of next generation tobacco and nicotine products, the generation, delivery and testing of undiluted aerosols can now be considered. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

AMEE Guide 32: e-Learning in medical education Part 1: Learning, teaching and assessment.

Science.gov (United States)

Ellaway, Rachel; Masters, Ken

2008-06-01

In just a few years, e-learning has become part of the mainstream in medical education. While e-learning means many things to many people, at its heart it is concerned with the educational uses of technology. For the purposes of this guide, we consider the many ways that the information revolution has affected and remediated the practice of healthcare teaching and learning. Deploying new technologies usually introduces tensions, and e-learning is no exception. Some wish to use it merely to perform pre-existing activities more efficiently or faster. Others pursue new ways of thinking and working that the use of such technology affords them. Simultaneously, while education, not technology, is the prime goal (and for healthcare, better patient outcomes), we are also aware that we cannot always predict outcomes. Sometimes, we have to take risks, and 'see what happens.' Serendipity often adds to the excitement of teaching. It certainly adds to the excitement of learning. The use of technology in support of education is not, therefore, a causal or engineered set of practices; rather, it requires creativity and adaptability in response to the specific and changing contexts in which it is used. Medical Education, as with most fields, is grappling with these tensions; the AMEE Guide to e-Learning in Medical Education hopes to help the reader, whether novice or expert, navigate them. This Guide is presented both as an introduction to the novice, and as a resource to more experienced practitioners. It covers a wide range of topics, some in broad outline, and others in more detail. Each section is concluded with a brief 'Take Home Message' which serves as a short summary of the section. The Guide is divided into two parts. The first part introduces the basic concepts of e-learning, e-teaching, and e-assessment, and then focuses on the day-to-day issues of e-learning, looking both at theoretical concepts and practical implementation issues. The second part examines technical

Maailma avanemise aasta / Juhan Parts

Index Scriptorium Estoniae

Parts, Juhan, 1966-

2004-01-01

Ilmunud ka: Põhjarannik, 29. dets. 2004, lk. 2; Severnoje Poberezhje, 29. dets. 2004, lk. 2; Pärnu Postimees, 30. dets. 2004, lk. 15; Nädaline, 31. dets. 2004, lk. 4; Narva Postiljon, 31. dets. 2004, lk. 2; Harjumaa, 31. dets. 2004, lk. 2; Virumaa Teataja, 31. dets. 2004, lk. 11; Hiiu Leht, 31. dets. 2004, lk. 2; Meie Maa, 31. dets. 2004, lk. 2. Peaminister teeb kokkuvõtte, mida on lõppev aasta Eestile toonud

Noor peab saama sõna sekka öelda / Gerri Lesk

Index Scriptorium Estoniae

Lesk, Gerri

2005-01-01

Ilmunud ka: Valgamaalane 25. okt., lk. 2, Harjumaa 25. okt., lk. 2, Vali Uudised 26. okt., lk. 2, Sõnumitooja 26. okt., lk. 2, Põhjarannik 26. okt., lk. 2, Severnoje Poberezhje 26. okt. lk. 2, Nädaline 27. okt. lk. 2, Virumaa Teataja 28. okt., lk. 7, Meie Maa 28. okt., lk. 2, Kuulutaja 28. okt. lk. 4, Lääne Elu 29. okt. lk. 2. Noorte Sotsiaaldemokraatide president teeb lõppenud kohalikest valimistest kokkuvõtte

Ühe näoga Janus / Mart Raukas

Index Scriptorium Estoniae

Raukas, Mart

2008-01-01

Tänapäeva lääne poliitikud, lähtudes oma avaldustes aina enam tüüpilistest moraalihinnangutest, unustavad, et ükski moraalne reageering ei ole pelgalt reageering faktidele, vaid selle teeb moraalselt relevantseks olukorrale langetatud hinnang ja sellest lähtuv reageering. Õigluseta ühiskond ei erine suurest röövlijõugust ning see, kes mõistab hukka ühe suurriigi tegevuse, olgu kriitiline ka teise suurjõu osas

Reflections About the Role of Intellectuals in Latin America Reflexiones acerca del rol de los intelectuales en América Latina Reflexões sobre o papel dos intelectuais na América Latina

Directory of Open Access Journals (Sweden)

Judith Naidorf

2010-10-01

intellectual debate but to contribute to a not new but always applicable, which should be a breakthrough for each of our practices in the different social areas in which we daily work.

Mida teeb Cattelani koer Taani paviljonis / Anneli Porri

Index Scriptorium Estoniae

Porri, Anneli, 1980-

2009-01-01

Põhjamaade (Norra, Rootsi, Soome) ja Taani paviljonis 53. Veneetsia kunstibiennaalil eksponeeritud kunstnike-kuraatorite Michael Elmgreeni ja Ingar Dragseti projektist "Kogujad". Kuraatoritöö auhinna pälvinud paviljoni puhul pöörab autor eelkõige tähelepanu just kahele paviljonile kui tervikule ja võimalikele vaatamisviisidele

Kas inflatsioon teeb Eestist euroliidu Zimbabwe? / Margus Sanglepp

Index Scriptorium Estoniae

Sanglepp, Margus, 1967-

2007-01-01

Eesti valitsus ei ole inflatsiooni pidurdamiseks abinõusid kasutusele võtnud. Lätis ei ole valitsuse püüe ohjeldada inflatsiooni tulemusi andnud. Vt. samas: Märten Ross. Riigi võimalused inflatsiooni mõjutamiseks

"Beverly Hills 90210" : kes mida teeb / Tiina Lepiste

Index Scriptorium Estoniae

Lepiste, Tiina

2003-01-01

Aaron Spellingu produtseeritud ja 2000. aastal lõpetatud menuseriaalis "Beverly Hills 90210" osalenud näitlejate edaspidisest elust seoses plaaniga teha täispikk mängufilm "10 Year High School Reunion"

Ämblik teeb investori elu kergemaks / Peeter Koppel

Index Scriptorium Estoniae

Koppel, Peeter

2002-01-01

Ilmunud ka: Molodjozh Estonii 12. november lk. 7, Delovõje Vedomosti 13. november lk. 33. Investorite tähelepanu all on börsil kaubeldavad investeerimisfondid (ETF), millest osa kannab näiteks ämbliku, teemandi või kuubiku nime

Taska teeb Venezuela seebi eesti moodi / Verni Leivak

Index Scriptorium Estoniae

Leivak, Verni, 1966-

2008-01-01

Produtsent Kristian Taska ostis ära Venezuela seebiooperi "Lorenzo naine", et valmistada Kanal Spordis näitamiseks Eesti oludele mugandatud "Kalevi naised" (lavastaja Ingomar Vihmar, osades Maria Avdjuško, Andrus Vaarik, Jan Uuspõld, Anne Reemann)

No-Big-Silence teeb klubituuri / Urmas Hännile

Index Scriptorium Estoniae

Hännile, Urmas

2009-01-01

Rockansamblist No-Big-Silence ja dark-popansamblist Sinine, nende kontsertttuurist mööda Eestimaad, tutvustamisel bändide uued albumid (No-Big-Silence "Starstealer" ja Sinine "Butterflies"), Pärnus on kontsert 24. oktoobril klubis Sugar

Valitsuskabinet teeb ettepaneku kinnitada Eesti Raudtee erastajaks BRS

Index Scriptorium Estoniae

2004-01-01

Majandus- ja kommunikatsiooniminister Meelis Atonen tutvustas valitsuskabineti liikmetele AS-i Eesti Raudtee erastamise otsuse eelnõu, millega tehakse ettepanek kinnitada parimaks pakkujaks Baltic Rail Service

Ajakirjanik teeb algupärast indiaanimuusikali / Verni Leivak

Index Scriptorium Estoniae

Leivak, Verni, 1966-

2004-01-01

Kanal2 uudistereporter Üllar Purre ja tema kaks kaaslast bändist Üle Saja laulavad linti omakirjutatud rokkooperit "Vikerkaar ehk Mata mu süda Wounded Knees". Lisaks kommentaar "Muusikaliprofid arvavad"

Mis ikkagi teeb Eestist Uganda? / Marja-Liisa Alop

Index Scriptorium Estoniae

Alop, Marja-Liisa

2006-01-01

Eesti üliõpilaskondade liidu juhatuse aseesimees M.-L. Alop kirjutab vastuse M. Heidmetsa artiklile 6. jaan. Eesti Päevalehes "Eestis nagu Ugandas", kus tõstatati Eestis üldise õppemaksu kehtestamise vajadus, mis vähendab vähem kindlustatute võimalusi kõrgharidust omandada

Citigroupi soovitus teeb Hansapanga aktsia kuulsaks / Annika Matson

Index Scriptorium Estoniae

Matson, Annika, 1976-

2005-01-01

Maailma suurim pank Citigroup soovitab osta Hansapanga aktsiaid ning kiidab panga kiiret kasvu regioonis ja esmaklassilist juhtimistiimi. Kommenteerivad: Rain Lõhmus, Jüri Mõis, Heldur Meerits. Vt. samas: Ka Leedu Hansabankas tõi hea uudise; Tõnis Oja. Hansapank Wall Streeti suurtegija huviorbiidis

Apteekri nõu teeb kauba kalliks / Kadri Jakobson

Index Scriptorium Estoniae

Jakobson, Kadri, 1970-

2008-01-01

Ilmunud ka: Delovõje Vedomosti 9. juuli lk. 28. Hinnakujundus apteegis sõltub asukohast ja klientide ostujõust, samuti tuleneb hind sellest, et apteek müüb erialaspetsialisti nõuannet, mida kaubakeskusest ei saa. Kommenteerib Tea Siimon

Results of a jet plume effects test on Rockwell International integrated space shuttle vehicle using a vehicle 5 configuration 0.02-scale model (88-OTS) in the 11 by 11 foot leg of the NASA/Ames Research Center unitary plan wind tunnel (IA19), volume 1

Science.gov (United States)

Nichols, M. E.

1975-01-01

Results are presented of jet plume effects test IA19 using a vehicle 5 configuration integrated space shuttle vehicle 0.02-scale model in the NASA/Ames Research Center 11 x 11-foot leg of the unitary plan wind tunnel. The jet plume power effects on the integrated vehicle static pressure distribution were determined along with elevon, main propulsion system nozzle, and solid rocket booster nozzle effectiveness and elevon hinge moments.

M2-F1 mounted in NASA Ames Research Center 40x80 foot wind tunnel

Science.gov (United States)

1962-01-01

After the first attempted ground-tow tests of the M2-F1 in March 1963, the vehicle was taken to the Ames Research Center, Mountain View, CA, for wind-tunnel testing. During these tests, Milt Thompson and others were in the M2-F1 to position the control surfaces for each test. The wingless, lifting body aircraft design was initially conceived as a means of landing an aircraft horizontally after atmospheric reentry. The absence of wings would make the extreme heat of re-entry less damaging to the vehicle. In 1962, Dryden management approved a program to build a lightweight, unpowered lifting body as a prototype to flight test the wingless concept. It would look like a 'flying bathtub,' and was designated the M2-F1, the 'M' referring to 'manned' and 'F' referring to 'flight' version. It featured a plywood shell placed over a tubular steel frame crafted at Dryden. Construction was completed in 1963. The first flight tests of the M2-F1 were over Rogers Dry Lake at the end of a tow rope attached to a hopped-up Pontiac convertible driven at speeds up to about 120 mph. This vehicle needed to be able to tow the M2-F1 on the Rogers Dry Lakebed adjacent to NASA's Flight Research Center (FRC) at a minimum speed of 100 miles per hour. To do that, it had to handle the 400-pound pull of the M2-F1. Walter 'Whitey' Whiteside, who was a retired Air Force maintenance officer working in the FRC's Flight Operations Division, was a dirt-bike rider and hot-rodder. Together with Boyden 'Bud' Bearce in the Procurement and Supply Branch of the FRC, Whitey acquired a Pontiac Catalina convertible with the largest engine available. He took the car to Bill Straup's renowned hot-rod shop near Long Beach for modification. With a special gearbox and racing slicks, the Pontiac could tow the 1,000-pound M2-F1 110 miles per hour in 30 seconds. It proved adequate for the roughly 400 car tows that got the M2-F1 airborne to prove it could fly safely and to train pilots before they were towed behind a C

Short outlines of books by Estonian authors / Rutt Hinrikus, Janika Kronberg

Index Scriptorium Estoniae

Hinrikus, Rutt, 1946-

2000-01-01

Andres Ehin. Alateadvus on alatasa purjus; Peeter Torop. Kultuurimärgid; Matt Barker. Sarah' jalad; Jaan Isotamm. Mina Johnny B.; Jaan Kaplinski. Silm. Hektor; Jaan Kaplinski. Kevad kahel rannikul ehk tundeline teekond Ameerikasse; Rein Raud. Pisiasjad, mis omavad tähtsust; Kerttu Rakke. Kalevipoeg; Elin Toona. Rõõm teeb taeva taga tuld; Veera Saar. Neid ammuseid aegu; Toomas Vint. Nädalavahetusel. Mängides; Varjatud ilus haigus : valik sajandilõpu eesti luuletajaid / koostanud Kajar Pruul; Viiu Härm. Duubel kaks

29. IX-16. X on Kütioru ja Groningeni (Holland) vahel sateliidisild

Index Scriptorium Estoniae

2005-01-01

Peeter Laurits ja Katz töötavad näitusega "Voolav labürint" Kütiorus ning Groningenis projitseeritakse selle protsessi videopilt kahele ekraanile Vroom & Dreesmanni kaubamaja seinal. Näitusega seotud üritused Kütiorus: Anne Türnpu lavastatud "Lemminkäinen" lavakunstikooli üliõpilaste esituses, Triinu Lille maastikuinstallatsiooni rajamine jpm. Projektist teeb dokumentaalfilmi Mart Arjukese. Projekti initsiaator ja läbiviija: Pavlov Medialab. 27. X avatakse näitus Tallinnas Ühispanga galeriis

Võitlus suhkru pärast / Bartholomäus Grilli, Petra Pinzler, Ralf Südhoff...[jt.] ; tõlk. Erik Aru

Index Scriptorium Estoniae

2005-01-01

Autorite väitel said Euroopa suhkruturu korraldusest kasu nii Euroopa talunik kui ka Aafrika põllupidaja. Kui EL vähendab suhkru garanteeritud hinda, vähenevad ka Mosambiigi suhkrurookasvatajate tulud. Samas teeb suhkrutootmine rikkaks paljud Brasiilia suhkrurooistanduste omanikud. Autorite sõnul demonstreerib suhkru näide, et maailmaturgu ei huvita mitte see, kes mida vajab, vaid see, kus on kõige väiksemad kulud. Lisa: Eurooplastelt võetakse aastas 6,5 miljardit eurot

Results of a M = 5.3 heat transfer test of the integrated vehicle using phase-change paint techniques on the 0.0175-scale model 56-OTS in the NASA/Ames Research Center 3.5-foot hypersonic wind tunnel

Science.gov (United States)

Marroquin, J.

1985-01-01

An experimental investigation was performed in the NASA/Ames Research Center 3.5-foot Hypersonic Wind Tunnel to obtain supersonic heat-distribution data in areas between the orbiter and external tank using phase-change paint techniques. The tests used Novamide SSV Model 56-OTS in the first and second-stage ascent configurations. Data were obtained at a nominal Mach number of 5.3 and a Reynolds number per foot of 5 x 10 to the 6th power with angles of attack of 0 deg, +/- 5 deg, and sideslip angles of 0 deg and +/- 5 deg.

Piloted Evaluation of Modernized Limited Authority Control Laws in the NASA-Ames Vertical Motion Simulator (VMS)

Science.gov (United States)

Sahasrabudhe, Vineet; Melkers, Edgar; Faynberg, Alexander; Blanken, Chris L.

2003-01-01

The UH-60 BLACK HAWK was designed in the 1970s, when the US Army primarily operated during the day in good visual conditions. Subsequently, the introduction of night-vision goggles increased the BLACK HAWK'S mission effectiveness, but the accident rate also increased. The increased accident rate is strongly tied to increased pilot workload as a result of a degradation in visual cues. Over twenty years of research in helicopter flight control and handling qualities has shown that these degraded handling qualities can be recovered by modifying the response type of the helicopter in low speed flight. Sikorsky Aircraft Corporation initiated a project under the National Rotorcraft Technology Center (NRTC) to develop modern flight control laws while utilizing the existing partial authority Stability Augmentation System (SAS) of the BLACK HAWK. This effort resulted in a set of Modernized Control Laws (MCLAWS) that incorporate rate command and attitude command response types. Sikorsky and the US Army Aeroflightdynamics Directorate (AFDD) conducted a piloted simulation on the NASA-Ames Vertical h4otion Simulator, to assess potential handling qualities and to reduce the risk of subsequent implementation and flight test of these modern control laws on AFDD's EH-60L helicopter. The simulation showed that Attitude Command Attitude Hold control laws in pitch and roll improve handling qualities in the low speed flight regime. These improvements are consistent across a range of mission task elements and for both good and degraded visual environments. The MCLAWS perform better than the baseline UH-60A control laws in the presence of wind and turbulence. Finally, while the improved handling qualities in the pitch and roll axis allow the pilot to pay more attention to the vertical axis and hence altitude performance also improves, it is clear from pilot comments and altitude excursions that the addition of an Altitude Hold function would further reduce workload and improve overall

Evaluación de métodos para la conservación de hongos fitopatógenos del ñame (Dioscorea sp.

Directory of Open Access Journals (Sweden)

Yeimy Alexandra Pinzón Gutiérrez

2009-07-01

Full Text Available Un elemento esencial en la investigación con microorganismos fitopatógenos es su conservación y uso seguro. Desde este punto de vista, en este estudio se evaluaron métodos de conservación de hongos que atacan el ñame, empleando como factores de respuesta el potencial de viabilidad, y la estabilidad y presencia o ausencia de cambios en las características macro y microscópicas. Como resultado del trabajo se proponen los métodos más adecuados para los géneros Colletotrichum y Fusarium, hongos causantes de las mayores pérdidas en las plantaciones de ñame en la Costa Caribe colombiana. Las cepas utilizadas en este estudio provienen de las colecciones de la Universidad de Sucre, del Instituto de Biotecnología de la Universidad Nacional de Colombia (IBUN y de una donación de la doctora Lucía Afanador de la Universidad Nacional, Sede Medellín. Estas fueron sometidas a diferentes métodos de conservación, entre ellos criopreservación, liofilización y cultivo periódico con y sin aceite mineral. Los resultados obtenidos permitieron elegir la criopreservación como el método más eficiente para la conservación de la colección, y el cultivo periódico con aceite mineral como método alternativo y complementario. Estos minimizan el riesgo de pérdida del material biológico y brindan condiciones de manejo que conservan las características biológicas bajo estudio desde campos como la microbiología, la bioquímica y la biología molecular, entre otros. An essential element in phytopathogenic microorganism research is their preservation and safe use. The purpose of this study was to evaluate methods for preserving fungi producing diseases in yam, using potential viability, stability and the presence or absence of macro- and microscopic characteristic changes as response factors. More suitable methods for Colletotrichum and Fusarium genera were proposed as a result of the work; these are fungi causing the greatest losses in yam

Report on the Stanford/KACST/AMES UVLED small satellite mission to demonstrate charge management of an electrically isolated proof mass for drag-free operation

Science.gov (United States)

Saraf, Shailendhar

A spacecraft demonstration of ultra-violet (UV) LEDs and UV LED charge management based on research done at Stanford University is being developed jointly by the King Abdulaziz City for Science and Technology (KACST) Saudi Arabia and NASA Ames Research Center, with an expected launch date of June 2014. This paper will report on the payload design and testing, mission preparation, satellite launch and payload bring -up in space. Mission lifetime is expected to be at least one month, during which time the ability for the UV LEDs to mitigate actual space-based charging and the effects of radiation on the UV LED device performance will be studied. Precise control over the potential of an electrically isolated proof mass is necessary for the operation of devices such as a Gravitational Reference Sensor (GRS) and satellite missions such as LISA. The mission will demonstrate that AlGaN UV LEDs operating at 255 nm are an effective low-cost, low-power and compact substitute for Mercury vapor lamps used in previous missions. The goal of the mission is to increase the UV LED device to TRL-9 and the charge management system to TRL-7.

AME survey-003 A1-part 2: the motivation factors of medical doctors in China.

Science.gov (United States)

Wáng, Yì-Xiáng J; Káplár, Zoltán; L, Yáo T

2015-12-01

The professional moral and job satisfaction of medical profession remain highly disputed in media in China. On the other hand, there is wide disaffection of patients toward doctors in China. This survey aims to obtain a better understanding of the motivation of Chinese medical professionals. An anonymous online cross-sectional survey, AME survey III, was conducted using the platform provided by DXY (www.dxy.cn) during the period of September 10-23, 2015. In total 2,356 DXY users completed the survey, including 1,740 males and 617 females, with a mean age of 31.96±7.03 yrs. The reasons (multiple choices) for career disaffection included poor patient/doctor relationship (88.6%), imbalance between workload and pay (79.5%), could not enter the preferred specialty (14.14%), and working in small clinics with no career progress (11.17%). If given the choice to enter the specialty as well as the hospital grade of their choice, 73.8% dissatisfied respondents replied they would like to be a doctor. For the dis-satisfied respondents, university teacher appeared to be the most popular career choice. The cited high workload was considered to be due to (I) imbalance in geographical allocation of doctors and insufficient training of doctors; (II) many red-tapism formalities; (III) Chinese patients often have unreasonable requests; (IV) over-examination and over-treatment; (V) high pressure to publish papers. One hundred and twelve respondents have their child/children attending university or graduated from university, 25.0% of them are pursuing a career in medicine. Nine hundred and ninety respondents have child/children while did not reach university age yet, among them 23.62% would like their child/children to study medicine. 64.87% of the 2,356 participants favor China to open up medical market to qualified foreign medical organizations to take part in fair competition, and 57.91% favor the government supporting regulated private hospitals. The moral and motivation of medical

Measurement of neutron spectra generated by a 62 AMeV carbon-ion beam on a PMMA phantom using extended range Bonner sphere spectrometers

International Nuclear Information System (INIS)

Bedogni, R.; Amgarou, K.; Domingo, C.; Russo, S.; Cirrone, G.A.P.; Pelliccioni, M.; Esposito, A.; Pola, A.; Introini, M.V.; Gentile, A.

2012-01-01

Neutrons constitute an important component of the radiation environment in hadron therapy accelerators. Their energy distribution may span from thermal up to hundred of MeV. The characterization of these fields in terms of dosimetric or spectrometric quantities is crucial for either the patient protection or the facility design aspects. To date, the Extended Range Bonner Sphere Spectrometer (ERBSS) is the only instrument able to simultaneously determine all spectral components in such workplaces. With the aim of providing useful data to the scientific community involved in neutron measurements at hadron therapy facilities, a measurement campaign was carried out at the Centro di AdroTerapia e Applicazioni Nucleari Avanzate (CATANA) of INFN-LNS (Laboratori Nazionali del Sud), where a 62 AMeV carbon ion is available. The beam was directed towards a PMMA phantom, simulating the patient, and two neutron measurement points were established at 0° and 90° with respect to the beam-line. The ERBSSs of UAB (Universidad Autónoma de Barcelona-Grup de Física de les Radiacions) and INFN (Istituto Nazionale di Fisica Nucleare-Laboratori Nazionali di Frascati) were used to measure the resulting neutron fields. The two ERBSSs use different detectors and sphere diameters, and have been independently calibrated. The FRUIT code was used to unfold the results.

Measurement of neutron spectra generated by a 62 AMeV carbon-ion beam on a PMMA phantom using extended range Bonner sphere spectrometers

Energy Technology Data Exchange (ETDEWEB)

Bedogni, R., E-mail: roberto.bedogni@lnf.infn.it [Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali di Frascati, Via E. Fermi 40, 00044 Frascati (Italy); Amgarou, K.; Domingo, C. [Grup de Recerca en Radiacions Ionitzants, Departament de Fisica, Universitat Autonoma de Barcelona, E-08193 Bellaterra (Spain); Russo, S.; Cirrone, G.A.P. [Istituto Nazionale di Fisica Nucleare-Laboratori Nazionali dei Sud, Via S. Sofia 62, 95125 Catania (Italy); Pelliccioni, M.; Esposito, A. [Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali di Frascati, Via E. Fermi 40, 00044 Frascati (Italy); Pola, A.; Introini, M.V. [Politecnico di Milano, CESNEF, Dipartimento di Energia, via Ponzio 34/3, 20133 Milano (Italy); Gentile, A. [Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali di Frascati, Via E. Fermi 40, 00044 Frascati (Italy)

2012-07-21

Neutrons constitute an important component of the radiation environment in hadron therapy accelerators. Their energy distribution may span from thermal up to hundred of MeV. The characterization of these fields in terms of dosimetric or spectrometric quantities is crucial for either the patient protection or the facility design aspects. To date, the Extended Range Bonner Sphere Spectrometer (ERBSS) is the only instrument able to simultaneously determine all spectral components in such workplaces. With the aim of providing useful data to the scientific community involved in neutron measurements at hadron therapy facilities, a measurement campaign was carried out at the Centro di AdroTerapia e Applicazioni Nucleari Avanzate (CATANA) of INFN-LNS (Laboratori Nazionali del Sud), where a 62 AMeV carbon ion is available. The beam was directed towards a PMMA phantom, simulating the patient, and two neutron measurement points were established at 0 Degree-Sign and 90 Degree-Sign with respect to the beam-line. The ERBSSs of UAB (Universidad Autonoma de Barcelona-Grup de Fisica de les Radiacions) and INFN (Istituto Nazionale di Fisica Nucleare-Laboratori Nazionali di Frascati) were used to measure the resulting neutron fields. The two ERBSSs use different detectors and sphere diameters, and have been independently calibrated. The FRUIT code was used to unfold the results.

Measurement of neutron spectra generated by a 62 AMeV carbon-ion beam on a PMMA phantom using extended range Bonner sphere spectrometers

Science.gov (United States)

Bedogni, R.; Amgarou, K.; Domingo, C.; Russo, S.; Cirrone, G. A. P.; Pelliccioni, M.; Esposito, A.; Pola, A.; Introini, M. V.; Gentile, A.

2012-07-01

Neutrons constitute an important component of the radiation environment in hadron therapy accelerators. Their energy distribution may span from thermal up to hundred of MeV. The characterization of these fields in terms of dosimetric or spectrometric quantities is crucial for either the patient protection or the facility design aspects. To date, the Extended Range Bonner Sphere Spectrometer (ERBSS) is the only instrument able to simultaneously determine all spectral components in such workplaces. With the aim of providing useful data to the scientific community involved in neutron measurements at hadron therapy facilities, a measurement campaign was carried out at the Centro di AdroTerapia e Applicazioni Nucleari Avanzate (CATANA) of INFN-LNS (Laboratori Nazionali del Sud), where a 62 AMeV carbon ion is available. The beam was directed towards a PMMA phantom, simulating the patient, and two neutron measurement points were established at 0° and 90° with respect to the beam-line. The ERBSSs of UAB (Universidad Autónoma de Barcelona-Grup de Física de les Radiacions) and INFN (Istituto Nazionale di Fisica Nucleare-Laboratori Nazionali di Frascati) were used to measure the resulting neutron fields. The two ERBSSs use different detectors and sphere diameters, and have been independently calibrated. The FRUIT code was used to unfold the results.

Na privatizatsionnom pereputje / Aleksei Zhigulin

Index Scriptorium Estoniae

Zhigulin, Aleksei

2006-01-01

Baltic Rail Service (BRS) nõukogu esimees Edward Burkhardt kinnitas rahandusminister Aivar Sõerdile saadetud kirjas, et Eesti Vabariigi valitsusel ei ole alust lõpetada Eesti Vabariigi ja BRS-i vahel sõlmitud Eesti Raudtee erastamislepingut. BRS esitas koos kirjaga valitsusele Eesti Raudtee uue äriplaani, mis kirjeldab ettevõtte tegevust ja investeeringuid raudtee infrastruktuuri ning ohutuse jätkuvasse parandamisse kuni aastani 2010. Plaani alusel teeb Eesti Raudtee lähiaastail juurde rohkem kui 2,1 miljardi krooni ulatuses uusi investeeringuid

Miks Coca-Cola enam ei kihise? / Neeme Raud

Index Scriptorium Estoniae

Raud, Neeme, 1969-

2004-01-01

Autor teeb USA äriajakirjanduse põhjal ülevaate Coca-Cola Company maine, turupositsiooni ja aktsiakursi langemise põhjustest alates 1997. aastast. Analüütikute sõnul on korporatsioon olnud ebaedukas tippkaadri voolavuse, sisekonfliktide, pidevate ümberkorralduste ja töötajate koondamiste tõttu. Praegune peadirektor Neville Isdelle on püstitanud eesmärgiks firma sisekultuuri parandamise, et keskenduda liidripositsiooni kindlustamisele turul. Diagramm: Karastusjookidel gaas väljas. Vt. samas: Coca-Cola ja Pepsi - üheskoos alla

Stereo Photogrammetry Measurements of the Position and Attitude of a Nozzle-Plume/Shock-Wave Interaction Model in the NASA Ames 9- by 7-Ft Supersonic Wind Tunnel

Science.gov (United States)

Schairer, Edward T.; Kushner, Laura K.; Drain, Bethany A.; Heineck, James T.; Durston, Donald A.

2017-01-01

Stereo photogrammetry was used to measure the position and attitude of a slender body of revolution during nozzle-plume/shock-wave interaction tests in the NASA Ames 9- by 7-Ft Supersonic Wind Tunnel. The model support system was designed to allow the model to be placed at many locations in the test section relative to a pressure rail on one sidewall. It included a streamwise traverse as well as a thin blade that offset the model axis from the sting axis. With these features the support system was more flexible than usual resulting in higher-than-usual uncertainty in the position and attitude of the model. Also contributing to this uncertainty were the absence of a balance, so corrections for sting deflections could not be applied, and the wings-vertical orientation of the model, which precluded using a gravity-based accelerometer to measure pitch angle. Therefore, stereo photogrammetry was chosen to provide independent measures of the model position and orientation. This paper describes the photogrammetry system and presents selected results from the test.

Ames and random amplified polymorphic DNA tests for the validation of the mutagenic and/or genotoxic potential of the drinking water disinfection by-products chloroform and bromoform.

Science.gov (United States)

Khallef, Messaouda; Cenkci, Süleyman; Akyil, Dilek; Özkara, Arzu; Konuk, Muhsin; Benouareth, Djamel Eddine

2018-01-28

Chloroform and Bromoform are two abundant trihalomethanes found in Algerian drinking water. The investigation of the mutagenic hazard of these disinfection by-products was studied by Ames test as prokaryotic bioassay to show their mutagenic effects. For this, Salmonella typhimurium TA98 and TA100 strains were employed. Both chloroform and bromoform showed a direct mutagenic effect since the number of revertant colonies gradually increase in dose-dependent manner with all concentrations tested with the two bacterial strains and these were both in the absence and presence of S9 metabolic activation. The genotoxic hazard was also studied by random amplified polymorphic DNA test on the root cells of Allium cepa as eukaryotic bioassay. DNA extracted from the roots of the onion were incubated at different concentrations of chloroform and bromoform and then amplified by polymerase chain reaction. This was based on demonstrating a major effect of disappearance of bands compared to roots incubated in the negative control (distilled water). The results showed that these two compounds affected genomic DNA by breaks although by mutations.

Participación política y violencia de género en América Latina

Directory of Open Access Journals (Sweden)

Laura Albaine

2014-07-01

Full Text Available Este artículo reflexiona a través del análisis de fac- tores socioculturales e institucionales sobre uno de los obstáculos más graves que condicionan la participación política de las mujeres en América Latina: El acoso y vio- lencia política en razón de género. Esta problemática es una nueva expresión que ha adoptado la violencia de gé- nero en la arena política que restringe el ejercicio de los derechos políticos de las mujeres y el derecho a vivir una vida libre de violencia. El acoso y violencia política se manifiesta más allá de los avances normativos logrados en la región orientados a generar condiciones de igualdad en términos de género en la participación política. En consecuencia, a las nor- mas que promueven el acceso de las mujeres a cargos de decisión, tales como cuotas o paridad, deben sumársele cuerpos legales que garanticen, además de sus derechos políticos, su seguridad y sus derechos humanos. AbstractThis paper focuses on a reflection and analysis of socio-cultural and institutional factors that affect wom- en’s political participation Latin America, such as gen- der-based harassment and violence. This problem is a new expression that has adopted gender-based violence in political arena, restricting not only the exercise of women’s political rights but also their right to live a life free of violence. Despite Latin American countries have enacted laws to create conditions in terms of gender equality in polit- ical participation, political harassment and violence still occurs. However, these policy actions are not enough to ensure women’s access to decision-making positions, such as quotas or parity; it must also be legal bodies to ensure, in addition to their political rights, their personal safety and human rights. 

Study of the heavy ions (Au+Au at 150 AMeV) collisions with the FOPI detector. Comparison with the Landau-Vlasov model; Etude des collisions d`ions lourds AU+AU a 150 A.MeV avec le detecteur FOPI. Comparaison avec le modele de Landau-Vlasov

Energy Technology Data Exchange (ETDEWEB)

Boussange, S

1995-09-15

In this thesis, heavy ions (Au+Au) collisions experiments are made at 150 AMeV.In the first part, a general study of the nuclear matter equation is presented. Then the used Landau-Vlasov theoretical model is describe. The third part presents the FOPI experience and the details of how to obtain this theoretical predictions (filter, cuts, corrections, possible centrality selections).At the end, experimental results and comparisons with the Landau-Vlasov model are presented. (TEC). 105 refs., 96 figs., 14 tabs.

A CASE AGAINST SPINNING PAHS AS THE SOURCE OF THE ANOMALOUS MICROWAVE EMISSION

Energy Technology Data Exchange (ETDEWEB)

Hensley, Brandon S.; Draine, B. T. [Department of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 (United States); Meisner, Aaron M., E-mail: brandon.s.hensley@jpl.nasa.gov [Berkeley Center for Cosmological Physics, Berkeley, CA 94720 (United States)

2016-08-10

We employ an all-sky map of the anomalous microwave emission (AME) produced by component separation of the microwave sky to study correlations between the AME and Galactic dust properties. We find that while the AME is highly correlated with all tracers of dust emission, the best predictor of the AME strength is the dust radiance. Fluctuations in the AME intensity per dust radiance are uncorrelated with fluctuations in the emission from polycyclic aromatic hydrocarbons (PAHs), casting doubt on the association between AME and PAHs. The PAH abundance is strongly correlated with the dust optical depth and dust radiance, consistent with PAH destruction in low density regions. We find that the AME intensity increases with increasing radiation field strength, at variance with predictions from the spinning dust hypothesis. Finally, the temperature dependence of the AME per dust radiance disfavors the interpretation of the AME as thermal emission. A reconsideration of other AME carriers, such as ultrasmall silicates, and other emission mechanisms, such as magnetic dipole emission, is warranted.

IBBY Eesti osakond 2007

Index Scriptorium Estoniae

2007-01-01

IBBY Eesti osakond esitas Astrid Lindgreni mälestusauhinna kandidaatideks kirjanik Aino Perviku, illustraatorid Regina Lukk-Toompere ja Ilon Wiklandi. Paabeli Torni auhinna pälvis Arvo Valton komi kirjaniku Vladimir Timini noorsooromaani "Vana-Permi poisi Tikö seiklused" eesti keelde tõlkimise eest. IBBY aunimekirja esitati A. Kivirähk raamatuga "Leiutajateküla Lotte", kunstnik Jüri Mildeberg illustratsioonidega raamatule "Ruttu tuttu" ja tõlkija Piret Saluri Hannu Mäkela raamatu "Härra Huu teeb aiatööd" tõlkimise eest

Юрий Кушпело, дважды актер и орел стриптиза / интервьюировал Николай Караев

Index Scriptorium Estoniae

Кушпело, Юрий

2011-01-01

Riia Domino Theatre on 11. apr. külalisetendusel Vene Kultuurikeskuses lavastusega "Орлы стриптиза или Как наши парни в борьбе с кризисом до конца пошли...", lavastaja Oleg Šapošnikov. Intervjuu näitleja Juri Kušpeloga, kes teeb selles lavastuses rolli

Estonia hukk jõuab kinolinale / Anari Koppel

Index Scriptorium Estoniae

Koppel, Anari

2003-01-01

Saksamaal esilinastub 2. oktoobril poliitiline põnevusfilm "Balti torm" ("Baltic Storm"), mis kujutab parvlaev "Estonia" hukku venelaste vandenõu tulemusena. Film jõuab Eestis linale novembri alul. Produtsendid on Jutta Rabe ja Kaj Holmberg, režissöör ja üks stsenariste Reuben Leder, peaosades Greta Scacchi ja Jürgen Prochnow. Kaasa teeb ka Donald Sutherland USA kindrali rollis. Eesti näitlejaist teevad kaasa Rein Oja ja väikeses rollis Urmas Alenderi lesk Helje Kaskel. Kõlab ka U. Alenderi laul

Molecular characterisation of Colombian yam germplasm by "DNA amplification fingerprinting (DAF" in radioactivo conditions Caracterización molecular del germoplasma de ñame colombiano utilizando "DNA Amplificaron Fingerprinting (DAF" en condiciones radiactivas

Directory of Open Access Journals (Sweden)

Bustamante Silvia L.

2003-12-01

sustainability for small-scale Colombian yam farmers.Para la realización de este trabajo se utilizaron muestras de la colección de ñame (Dioscorea spp. de la Universi­dad de Córdoba y algunas muestras provenientes del IITA (International Institute of Tropical Agriculture, Ibadan, Nigeria, con el fin de caracterizarlas molecularmente y complementar la información que se tiene de ellas. Dada la importancia del cultivo del ñame para los pequeños productores de la costa atlántica, surgió la propuesta de iniciar estudios moleculares en una primera etapa empleando técnicas como los AFLP En este trabajo, utilizan­do DNA amplificación "fingerprinting" (DAF, técnica basada en la PCR que utiliza oligos aleatorios que gene­ran patrones de bandeo característicos de cada individuo, se encontró que la diversidad de la población fue 0.0413 con una media de similaridad de 0.9587, lo cual indica que la colección de ñame existente en el país posee muy poca diversidad genética, y esto puede explicar parcialmente la vulnerabilidad del cultivo a plagas y enfer­medades, como sucedió a finales de la década de 1980 cuando la antracnosis prácticamente acabó con el cultivo en la costa atlántica colombiana. Es recomendable continuar con los estudios de caracterización utilizando una técnica de mayor poder de discriminación.

Mutagens from the cooking of food. III. Survey by Ames/Salmonella test of mutagen formation in secondary sources of cooked dietary protein

Energy Technology Data Exchange (ETDEWEB)

Bjeldanes, L F [Univ. of California, Berkeley; Morris, M M; Felton, J S; Healy, S; Stuermer, D; Berry, P; Timourian, H; Hatch, F T

1982-01-01

A survey of mutagen formation during the cooking of a variety of protein-rich foods that are minor sources of protein intake in the American diet is reported (see Bjeldanes, Morris, Felton et al. (1982) for survey of major protein foods). Milk, cheese, tofu and organ meats showed negligible mutagen formation except following high-temperature cooking for long periods of time. Even under the most extreme conditions, tofu, cheese and milk exhibited fewer than 500 Ames/Salmonella typhimurium revertants/100 g equivalents (wet weight of uncooked food), and organ meats only double that amount. Beans showed low mutagen formation after boiling followed by frying (with and without oil). Only boiling of beans followed by baking for 1 hr gave appreciable mutagenicity (3650 revertants/100 g equivalents). Seafood samples gave a variety of results: red snapper, salmon, trout, halibut and rock cod all gave more than 1000 revertants/100 g wet weight equivalents when pan-fried or griddle-fried for about 6 min/side. Baked or poached rock cod and deep-fried shrimp showed no significant mutagen formation. Broiled lamb chops showed mutagen formation similar to that in red meats tested in the preceding paper: 16,000 revertants/100 g equivalents. These findings show that as measured by bioassay in S. typhimurium, most of the food that are minor sources of protein in the American diet are also minor sources of cooking-induced mutagens.

Mutagens from the cooking of food. III. Survey by Ames/Salmonella test of mutagen formation in secondary sources of cooked dietary protein.

Science.gov (United States)

Bjeldanes, L F; Morris, M M; Felton, J S; Healy, S; Stuermer, D; Berry, P; Timourian, H; Hatch, F T

1982-08-01

A survey of mutagen formation during the cooking of a variety of protein-rich foods that are minor sources of protein intake in the American diet is reported (see Bjeldanes, Morris, Felton et al. (1982) for survey of major protein foods). Milk, cheese, tofu and organ meats showed negligible mutagen formation except following high-temperature cooking for long periods of time. Even under the most extreme conditions, tofu, cheese and milk exhibited fewer than 500 Ames/Salmonella typhimurium revertants/100 g equivalents (wet weight of uncooked food), and organ meats only double that amount. Beans showed low mutagen formation after boiling and boiling followed by frying (with and without oil). Only boiling of beans followed by baking for 1 hr gave appreciable mutagenicity (3650 revertants/100g equivalents). Seafood samples gave a variety of results: red snapper, salmon, trout, halibut and rock cod all gave more than 1000 revertants/100 g wet weight equivalents when pan-fried or griddle-fried for about 6 min/side. Baked or poached rock and deep-fried shrimp showed no significant mutagen formation. Broiled lamb chops showed mutagen formation similar to that in red meats tested in the preceding paper: 16,000 revertants/100 g equivalents. These findings show that as measured by bioassay in S. typhimurium, most of the foods that are minor sources of protein in the American diet are also minor sources of cooking-induced mutagens.

Adenomyoepithelioma of the breast with hemorrhagic change diagnosed as papiloma on core needle biopsy: A case report

Energy Technology Data Exchange (ETDEWEB)

Nam, Kyung Sun; Kim, Ji Young; Kim, Soung Hee; Bae, Kyung Eun; Lee, Ji Hae; Kang, Mi Jin; Jeong, Myeong Ja; Kim, Soo Hyun; Kim, Jae Hyung [Dept. of Radiology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul (Korea, Republic of)

2016-11-15

Adenomyoepithelioma (AME) is a rare disease entity that represents biphasic proliferation of ductal epithelial and myoepithelial cells. AME can be confused with other neoplasms including malignancy because AME has various cytologic characteristics and nonspecific radiologic features. We describe an unusual AME with hemorrhagic change that was diagnosed as papilloma on core needle biopsy three times previously. The imaging features of AME are also discussed here.

DILL teeb Tallinna kolmandas maailmas tuntuks / Virve Liivanõmm

Index Scriptorium Estoniae

Liivanõmm, Virve

2010-01-01

DILL on Euroopa kolme ülikooli (Oslo, Parma, Tallinna) ingliskeelne magistriõppekava peamiselt kolmandatest riikidest tudengitele, mida Euroopa Liit rahastab Erasmus Mundus programmi raames. Eestis koordineerib ja juhendab enamikku Tallinnas tehtavatest magistritöödest TLÜ infoteaduste instituudi lektor Sirje Virkus

Lasteraamatukoguhoidja teeb loomingulist tööd / Nelli Orgmaa

Index Scriptorium Estoniae

Orgmaa, Nelli

2010-01-01

Lasteraamatukogude tööst 2009. aastal, märksõnadeks töö väikelastega, koostöö partneritega ja Edgar Valteri 80. sünniaastapäeva tähistamine. Sisaldab maakondade lugejate, külastuste ja laenutuste statistikat

Eesti juurtega ameeriklane teeb filmi laulvast revolutsioonist / Sigrid Laev

Index Scriptorium Estoniae

Laev, Sigrid

2005-01-01

James Tusty ja tema abikaasa Maureen Castle teevad oma firmaga Mountain View Productions dokumentaalfilmi Eesti taasiseseisvumisest. Ameeriklaste kõrval on Eestist kaasprodutsendiks Artur Talvik. Filmi eelarve on üle 4 miljoni krooni

Armastus teeb tugevaks / Marina Laikjõe ; interv. Verni Leivak

Index Scriptorium Estoniae

Laikjõe, Marina, 1967-

2008-01-01

Turismifirma Tez Tour tegevjuht ning reisifirma Travel-In juht Marina Laikjõe vastab küsimustele, mis puudutavad tema tegevust ja karjääri turisminduses, suhteid kolleegidega ning perekonna toetust raske haigusega võitlemise ajal. Kommenteerivad Reet Kivi, Tiit Pärnik. Lisa: Marina Laikjõe

Hüppeline aktsiisitõus teeb ruumi salaviinale / Hindrek Riikoja

Index Scriptorium Estoniae

Riikoja, Hindrek

2007-01-01

Ilmunud ka: Postimees : na russkom jazõke 15. mai lk. 5. Konjunktuuriinstituudi uuringu järgi tarbis keskmine eestimaalane 2006. aastal 11, 4 liitrit 100 %-list alkoholi. Valitsuse plaanist tõsta alkoholiaktsiisi. Lisa: Suurem palk lubab rohkem juua

Film teeb USA valmistumise Iraagi okupatsiooniks maatasa / Neeme Raud

Index Scriptorium Estoniae

Raud, Neeme, 1969-

2007-01-01

Dokumentaalfilm "Lõppu ei ole näha" ("No End in Sight") : autor ja režissöör professor Charles Ferguson : Ameerika Ühendriigid 2007. Lisa: USA vead Iraagis. Vt. samas: Sunniidid lahkusid Iraagi valitsusest

Üliõpilasteater teeb nalja armastusega / Maarja Mänd

Index Scriptorium Estoniae

Mänd, Maarja

2008-01-01

Minski lavastaja Sergei Turbani lavastusest "Naljad armastusest" Anton Tshehhovi lühinäidendite "Juubel" ja "Abieluettepanek" ainetel Tartu Üliõpilasteatri näitlejate esituses. Esietendus 7. dets. Athena pööningusaalis

IKEA teeb panuse Briti ja Venemaa turule / Tõnis Arnover

Index Scriptorium Estoniae

Arnover, Tõnis, 1952-

2006-01-01

Rootsi mööblikontsern IKEA laiendab müügipindu Suurbritannias, Venemaal ja Jaapanis. Diagramm: Suurbritannia turg IKEA-le ka praegu tähtsuselt teine. Vt. samas: IKEA firmakultuur ei näe ette juhtivtöötajate poputamist

Miljonäriks teeb miljonäri mõtteviis

Index Scriptorium Estoniae

2002-01-01

Raamatu "Teie finantsisiksus: mis see on ja kuidas sellest kasu saada" autor Kathleen Guerney: "Kindlad inimtüübid on raha teenimisel ja kogumisel alati edukamad". Diagramm: Miljonäride arv Põhja-Ameereikas ja Euroopas vara suuruse järgi

Maian Kärmas teeb alguse Jõulujazzile Tartus / Lia Eller

Index Scriptorium Estoniae

Eller, Lia

2003-01-01

Jõulujazzi üritustest Tartus: Maian Kärmase kontserdist Sadamateatris "Tuigutuled", Arne Oidi 75. sünniaastapäeva tähistavast kontserdist Vanemuise kontserdisaalis 4. dets., ameerika ansambli Gold Company Sextet kontserdist 15. detsembril

Kui Thatcher kiidab ja Pinochet teeb pai / Erik Terk

Index Scriptorium Estoniae

Terk, Erik

2006-01-01

Thatcheri ja Reagani nimedega seostatav neoliberaalne revolutsioon on saanud piisavalt vanaks, et kujundada pilt, mis toimus ja kuhu see meid viib. See ongi uue neoliberalismiraamatu David Harvey. A Brief History of Neoliberalism aineks

Uinunud Alice'i toas teeb imesid lavamaagia / Jaanus Kaasik

Index Scriptorium Estoniae

Kaasik, Jaanus

2004-01-01

7. veebr. esietendus Vanemuises tantsulavastus "Alice imedemaal". Etendus põhineb briti kirjaniku L. Carrolli samanimelisel lasteraamatul, koreograaf M. Murdmaa, kunstnik K. Jancis ja muusika on kirjutanud ungari helilooja S. Kall̤s, Alice'i osa tantsib korealanna Hye Min Kim

Tõnu Talve teeb üle Eesti talvetuure / Ants Juske

Index Scriptorium Estoniae

Juske, Ants, 1956-2016

2009-01-01

Tõnu Talve maalinäitus "Kaev, tuhk ja torn" Keila Kultuurikeskuses. Külalisesinejad: Kohtla-Järve Kunstide Kooli õpilased ja nende juhendaja Aarne Hanni ning Harjumaa koolide õpetajad ja õpilased

Käsitöö teeb asjad paremaks / Karin Paulus

Index Scriptorium Estoniae

Paulus, Karin, 1975-

2007-01-01

Eesti ja inglise kunstnike ühisnäitusest "Minu maailm : uus subjektiivsus kaasaegses disainis" Eesti Tarbekunsti- ja Disainimuuseumis. Kuraatorid Emily Campell, Andree Cook, Kai Lobjakas. Eksponeeritakse Annike Laigo, Krista Leesi, Ülle Jehe, Kärt Ojavee töid. Inglismaad esindavad 7 kunstnikku, lähemalt Danny Browni ja Alison Willoughby töödest

Developing the Infrared PAH Emission Bands Into Calibrated Probes of Astrophysical Conditions with The NASA Ames PAH IR Spectroscopic Database

Science.gov (United States)

Boersma, Christiaan

We propose to quantitatively calibrate the PAH band strength ratios that have been traditionally used as qualitative proxies of PAH properties and linking PAH observables with local astrophysical conditions, thus developing PAHs into quantitative probes of astronomical environments. This will culminate in a toolbox (calibration charts) that can be used by PAH experts and non-PAH experts alike to unlock the information hidden in PAH emission sources that are part of the Spitzer and ISO archives. Furthermore, the proposed work is critical to mine the treasure trove of information JWST will return as it will capture, for the first time, the complete mid-infrared (IR) PAH spectrum with fully resolved features, through a single aperture, and along single lines-of-sight; making it possible to fully extract the information contained in the PAH spectra. In short, the work proposed here represents a major step in enabling the astronomical PAH model to reach its full potential as a diagnostic of the physical and chemical conditions in objects spanning the Universe. Polycyclic aromatic hydrocarbons (PAHs), a common and important reservoir of accessible carbon across the Universe, play an intrinsic part in the formation of stars, planets and possibly even life itself. While most PAH spectra appear quite similar, they differ in detail and contain a wealth of untapped information. Thanks to recent advances in laboratory studies and computer-based calculations of PAH spectra, the majority of which have been made at NASA Ames, coupled with the astronomical modeling tools we have developed, we can interpret the spectral details at levels never before possible. This enables us to extract local physical conditions and track subtle changes in these conditions at levels previously impossible. Building upon the tools and paradigms developed as part of the publicly available NASA Ames PAH IR Spectroscopic Database (PAHdb; www.astrochem.org/pahdb/), the purpose of our proposed research is

Muusika : Stephan Oliva kvartett Eestis. Yamaha stipendium Hando Nahkurile. Eespere neljas autoriplaat. Uus rahvamuusikafestival. Uus orel uude kirikusse! Valga klaveriansamblite festival. Rahvusooperi poistekoor kutsub / Marje Laugen

Index Scriptorium Estoniae

Laugen, Marje

2002-01-01

Prantsuse dzhässpianist Stephan Oliva annab oma kvartetiga Eestis 6 kontserti. Yamaha konkursi stipendiumi võitis EMA I kursuse klaveri eriala üliõpilane Hando Nahkur. Rene Eespere neljanda autoriplaadi "Skulptuuri hommik" esitletakse EMA suures kammersaalis. 7.-9. märtsini saavad Tartus ja Tallinnas teoks muusikapäevad "MAA ja ILM". Kontserdisarjas "Orel kirikusse!" teeb järjekordse panuse Tallinna Metodisti kiriku oreli heaks Raekoja kammerkoor oma kontserdiga. 16. ja 17. veebr. Valga muusikakoolis toimunud VII rahvusvahelisest laste- ja noorte klaveriansamblite festivalist. Rahvusooperi poistekoor kutsub oma ridadesse uusi lauljaid

Palestiinlaste katastroof : Iisraeli asundused ja äärmuslik Hamas / Ivar Soopan

Index Scriptorium Estoniae

Soopan, Ivar, 1971-

2007-01-01

Äärmusrühmituse Hamas võit 2006. aastal Palestiina parlamendivalimistel näitas, et rahvas oli väsinud korrumpeerunud võimust, samas ei pööratud tähelepanu sellele, et Hamas kasutab oma eesmärkide saavutamiseks vägivalda. Palestiina teabeminister Mustafa Barghout taunib, et Iisrael ei võta Palestiina valitsust kui ühtset võimu, vaid teeb vahet Hamasi ja teiste poliitiliste jõudude ministritel. Palestiinlane Ala Shehadeh palestiinlaste intifadadest, juudi asunduste probleemist. Vt. samas: Miks Palestiinas elatakse nagu sada aastat tagasi?

Model Deformation Measurements of Sonic Boom Models in the NASA Ames 9- by 7-Ft Supersonic Wind Tunnel

Science.gov (United States)

Schairer, Edward T.; Kushner, Laura K.; Garbeff, Theodore J.; Heineck, James T.

2015-01-01

The deformations of two sonic-boom models were measured by stereo photogrammetry during tests in the 9- by 7-Ft Supersonic Wind Tunnel at NASA Ames Research Center. The models were geometrically similar but one was 2.75 times as large as the other. Deformation measurements were made by simultaneously imaging the upper surfaces of the models from two directions by calibrated cameras that were mounted behind windows of the test section. Bending and twist were measured at discrete points using conventional circular targets that had been marked along the leading and trailing edges of the wings and tails. In addition, continuous distributions of bending and twist were measured from ink speckles that had been applied to the upper surfaces of the model. Measurements were made at wind-on (M = 1.6) and wind-off conditions over a range of angles of attack between 2.5 deg. and 5.0 deg. At each condition, model deformation was determined by comparing the wind-off and wind-on coordinates of each measurement point after transforming the coordinates to reference coordinates tied to the model. The necessary transformations were determined by measuring the positions of a set of targets on the rigid center-body of the models whose model-axes coordinates were known. Smoothly varying bending and twist measurements were obtained at all conditions. Bending displacements increased in proportion to the square of the distance to the centerline. Maximum deflection of the wingtip of the larger model was about 5 mm (2% of the semispan) and that of the smaller model was 0.9 mm (1% of the semispan). The change in wing twist due to bending increased in direct proportion to distance from the centerline and reached a (absolute) maximum of about -1? at the highest angle of attack for both models. The measurements easily resolved bending displacements as small as 0.05 mm and bending-induced changes in twist as small as 0.05 deg.

Optimum O2:CH4 Ratio Promotes the Synergy between Aerobic Methanotrophs and Denitrifiers to Enhance Nitrogen Removal

Directory of Open Access Journals (Sweden)

Jing Zhu

2017-06-01

Full Text Available The O2:CH4 ratio significantly effects nitrogen removal in mixed cultures where aerobic methane oxidation is coupled with denitrification (AME-D. The goal of this study was to investigate nitrogen removal of the AME-D process at four different O2:CH4 ratios [0, 0.05, 0.25, and 1 (v/v]. In batch tests, the highest denitrifying activity was observed when the O2:CH4 ratio was 0.25. At this ratio, the methanotrophs produced sufficient carbon sources for denitrifiers and the oxygen level did not inhibit nitrite removal. The results indicated that the synergy between methanotrophs and denitrifiers was significantly improved, thereby achieving a greater capacity of nitrogen removal. Based on thermodynamic and chemical analyses, methanol, butyrate, and formaldehyde could be the main trophic links of AME-D process in our study. Our research provides valuable information for improving the practical application of the AME-D systems.

Alcohol Mixed with Energy Drinks: Daily Context of Use.

Science.gov (United States)

Linden-Carmichael, Ashley N; Lau-Barraco, Cathy

2017-04-01

The link between use of alcohol mixed with energy drinks (AmEDs) and alcohol-related harms is well established, but limited research has examined the context in which AmEDs are consumed. Identifying the social and environmental characteristics of use may illuminate whether AmEDs are used in settings that could increase the likelihood of engaging in risky behaviors or experiencing harms. This study used a 2-week daily diary assessment to compare days in which AmEDs were consumed ("AmED days") and days where other types of alcohol were used ("non-AmED days") on where, when, and with whom drinking occurred. Participants were 122 (90 women) heavy drinking college students who reported mixing caffeine with alcohol at least once in the past week. Data were collected across 389 drinking days; 40 of these days involved AmED use. Multilevel modeling findings revealed that odds of drinking AmEDs were higher on days where individuals drank at a bar or club and drank at home relative to other locations. In addition, odds of pregaming were higher on AmED days as compared to non-AmED days. AmED use was linked with lower odds of drinking game behavior. Overall, AmEDs appear to be consumed in potentially risky contexts. In combination with prior findings that AmED days are linked with heavier alcohol use and more harms experienced, these findings support the unique nature of AmED consumption in terms of the factors that may predict or maintain potentially hazardous drinking patterns. Copyright © 2017 by the Research Society on Alcoholism.

Daily conformity drinking motivations are associated with increased odds of consuming alcohol mixed with energy drinks.

Science.gov (United States)

Linden-Carmichael, Ashley N; Lau-Barraco, Cathy

2018-04-01

Recent research indicates that individuals drank more heavily and experienced more harms on days they consumed alcohol mixed with energy drinks (AmEDs). Limited research, thus far, has examined predictors of AmED use on a daily level. Drinking motives, or reasons for drinking, are shown to discern AmED users from non-users, but the extent to which daily drinking motives covary with AmED use has not been tested. The current study used a daily diary design to determine how motives differ between AmED and other drinking occasions. Participants included 122 college students (73.8% women) with a mean age of 20.39years. Participants completed up to 14 daily surveys, resulting in 389 drinking days (40days involved AmED use). Participants reported on their drinking motives at baseline as well as on each drinking day. Multilevel models revealed that, after controlling for other motives, AmED use was more likely on days where conformity motives were higher than usual and was less likely when enhancement motives were higher. Daily social and coping motives as well as all motives measured at baseline were unassociated with AmED use. Our findings suggest that conformity motives, or drinking to fit in with others, are the most salient drinking motive predicting AmED use on a drinking day. Given that conformity motives are often less associated with alcohol use outcomes in general, these findings highlight AmEDs as a unique alcoholic beverage. Clinicians and interventionists working with frequent AmED users should consider the unique conditions under which AmEDs are consumed. Copyright © 2017 Elsevier Ltd. All rights reserved.

Ciencéame

OpenAIRE

Rivera Castaño, José Juan

2014-01-01

En la actualidad las redes sociales son el medio de comunicación más utilizado dentro del mundo que rodea a Internet, ya que aporta a la sociedad un canal de interacción amplio y fluido, el cual se construye a través de un intercambio de información entre grupos de personas, instituciones, entidades y organizaciones. La importancia de la comunicación en la red ha sido tal, que la industria del software ha realizado grandes esfuerzos para pasar de sitios webs como los blogs dond...

Ames Air Revitalization

Science.gov (United States)

Huang, Roger Z.

2015-01-01

This is an informal presentation presented to the University of Colorado, Boulder Bioastronautics group seminar. It highlights the key focal areas of the Air Revitalization Group research over the past year, including progress on the CO2 Removal and Compression System, testing of CDRA drying bed configurations, and adsorption research.

CARACTERÍSTICAS FISICOQUÍMICAS Y MORFOLÓGICAS DE RIZÓFOROS DE ÑAME (Dioscorea alata) CARACTERÍSTICAS FÍSICOQUÍMICAS E MORFOLÓGICAS DE RIZÓFOROS DE INHAME (Dioscorea alata) PHYSICOCHEMICAL AND MORPHOLOGIC CHARACTERISTICS OF THE RIZÓFOROS OF YAM (Dioscorea alata)

OpenAIRE

CLÁUDIA DENISE DE PAULA; MÔNICA PIROZI; MARIO PUIATTI; JOÃO T. BORGES; ALBA M. DURANGO

2012-01-01

En este trabajo se determino la composición físico-química y las características morfológicas de los rizóforos de seis variedades de ñame (Dioscorea alata) del Banco de Germoplasma de Hortalizas (BGH) de la Universidade Federal de Viçosa (UFV). Fue determinada la composición centesimal mediante análisis de humedad, lípidos, proteína, cenizas, fibra bruta y carbohidratos. Las características morfológicas fueron estudiadas visualmente y por análisis microscópicos. La composición físico-química ...

Proposed Use of the NASA Ames Nebula Cloud Computing Platform for Numerical Weather Prediction and the Distribution of High Resolution Satellite Imagery

Science.gov (United States)

Limaye, Ashutosh S.; Molthan, Andrew L.; Srikishen, Jayanthi

2010-01-01

The development of the Nebula Cloud Computing Platform at NASA Ames Research Center provides an open-source solution for the deployment of scalable computing and storage capabilities relevant to the execution of real-time weather forecasts and the distribution of high resolution satellite data to the operational weather community. Two projects at Marshall Space Flight Center may benefit from use of the Nebula system. The NASA Short-term Prediction Research and Transition (SPoRT) Center facilitates the use of unique NASA satellite data and research capabilities in the operational weather community by providing datasets relevant to numerical weather prediction, and satellite data sets useful in weather analysis. SERVIR provides satellite data products for decision support, emphasizing environmental threats such as wildfires, floods, landslides, and other hazards, with interests in numerical weather prediction in support of disaster response. The Weather Research and Forecast (WRF) model Environmental Modeling System (WRF-EMS) has been configured for Nebula cloud computing use via the creation of a disk image and deployment of repeated instances. Given the available infrastructure within Nebula and the "infrastructure as a service" concept, the system appears well-suited for the rapid deployment of additional forecast models over different domains, in response to real-time research applications or disaster response. Future investigations into Nebula capabilities will focus on the development of a web mapping server and load balancing configuration to support the distribution of high resolution satellite data sets to users within the National Weather Service and international partners of SERVIR.

Motives for mixing alcohol with energy drinks and other non-alcoholic beverages and its effects on overall alcohol consumption among UK students.

Science.gov (United States)

Johnson, Sean J; Alford, Chris; Verster, Joris C; Stewart, Karina

2016-01-01

A UK student survey examined the motivations for consuming energy drinks alone and mixed with alcohol, and aimed to determine whether the type of motive had a differential effect on overall alcohol consumption. The online survey (N = 1873) assessed alcohol consumption and motivations for consumption when mixed with energy drinks (AMED) and mixed with other non-alcoholic beverages (AMOB) using a within-subject design. The most frequent neutral motives reported for AMED consumption included "I like the taste" (66.5%), and "to celebrate a special occasion" (35.2%). 52.6% of AMED consumers reported consuming AMED for at least one of five negative motives, primarily "to get drunk" (45.6%). Despite these negative motives those students reported consuming significantly less alcohol and fewer negative alcohol-related consequences on AMED occasions compared to alcohol-only (AO) occasions. Although the motives for consuming AMED and AMOB were comparable, more participants reported consuming AMED "to celebrate a special occasion", "to get drunk", because they "received the drink from someone else" or "because others drink it as well". However, significantly more students reported consuming AMOB than AMED because "It feels like I can drink more alcohol". Alcohol consumption was significantly less on AMED occasions compared to AMOB occasions, and both occasions significantly less than AO occasions. The majority of reasons for consuming AMED relate to neutral motives. Although 52.6% of students reported one or more negative motives for AMED consumption (predominantly "to get drunk") this had no differential effect on total alcohol consumption. The differences in motives suggest AMED is consumed more to enjoy special occasions and as a group-bonding experience, however alcohol consumption is significantly lower on such occasions in comparison to when AMOB or AO are consumed. Copyright © 2015. Published by Elsevier Ltd.

Alcohol Mixed with Energy Drinks: Consumption Patterns and Motivations for Use in U.S. College Students

Directory of Open Access Journals (Sweden)

Cecile A. Marczinski

2011-08-01

Full Text Available Binge drinking in college students is widespread and known to cause significant harms and health hazards for the drinker. One factor that may be exacerbating hazardous drinking in young people is the new popular trend of consuming alcohol mixed with energy drinks (AmED. However, rates of AmED use and motivations for AmED consumption in college students have not been well established. In this study, 706 undergraduate college students from a university in the United States participated in a web-based survey that queried self-reported alcohol, energy drink, and AmED use. In addition, motivations for using AmEDs were assessed. The results indicated that for all participants, 81% reported that they have tried at least one energy drink in the past and 36% reported consumption of at least one energy drink in the past 2 weeks. Alcohol consumption patterns were similar to findings from U.S. national surveys of college drinking, as 37% of respondents were classified as binge drinkers and 23% abstained from drinking. In the whole sample (including the alcohol abstainers, 44% reported trying AmED at least once and 9% reported AmED consumption at least once in the past 2 weeks. 78% of respondents agreed with the statement that AmEDs appeal to underage drinkers. When AmED users were asked about various motivations for consuming AmEDs, users reported that they consumed these beverages to get drunk and reduce sedation compared to alcohol alone. In conclusion, the consumption of AmEDs is common in U.S. college students. Motivations for using AmEDs include the reduction of the sedative effects of alcohol, an important interoceptive cue that one should stop drinking.

Alcohol mixed with energy drinks: consumption patterns and motivations for use in U.S. college students.

Science.gov (United States)

Marczinski, Cecile A

2011-08-01

Binge drinking in college students is widespread and known to cause significant harms and health hazards for the drinker. One factor that may be exacerbating hazardous drinking in young people is the new popular trend of consuming alcohol mixed with energy drinks (AmED). However, rates of AmED use and motivations for AmED consumption in college students have not been well established. In this study, 706 undergraduate college students from a university in the United States participated in a web-based survey that queried self-reported alcohol, energy drink, and AmED use. In addition, motivations for using AmEDs were assessed. The results indicated that for all participants, 81% reported that they have tried at least one energy drink in the past and 36% reported consumption of at least one energy drink in the past 2 weeks. Alcohol consumption patterns were similar to findings from U.S. national surveys of college drinking, as 37% of respondents were classified as binge drinkers and 23% abstained from drinking. In the whole sample (including the alcohol abstainers), 44% reported trying AmED at least once and 9% reported AmED consumption at least once in the past 2 weeks. 78% of respondents agreed with the statement that AmEDs appeal to underage drinkers. When AmED users were asked about various motivations for consuming AmEDs, users reported that they consumed these beverages to get drunk and reduce sedation compared to alcohol alone. In conclusion, the consumption of AmEDs is common in U.S. college students. Motivations for using AmEDs include the reduction of the sedative effects of alcohol, an important interoceptive cue that one should stop drinking.

Space Shuttle AFRSI OMS pod environment test using model 81-0 test fixture in the Ames Research Center 9x7-foot supersonic wind tunnel (OS-314A/B/C)

Science.gov (United States)

Collette, J. G. R.

1984-01-01

A test was conducted in the NASA/Ames Research Center 9x7-foot Supersonic Wind Tunnel to help resolve an anomaly that developed during the STS-6 orbiter flight wherein sections of the Advanced Flexible Reusable Surface Insulation (AFRSI) covering the OMS pods suffered some damage. A one-third scale two-dimensional shell structure model of an OMS pod cross-section was employed to support the test articles. These consisted of 15 AFRSI blanket panels form-fitted over the shell structures for exposure to simulated flight conditions. Of six baseline blankets, two were treated with special surface coatings. Two other panels were configured with AFRSI sections removed from the OV099 orbiter vehicle after the STS-6 flight. Seven additional specimens incorporated alternative designs and repairs. Following a series of surface pressure calibration runs, the specimens were exposed to simulated ascent and entry dynamic pressure profiles. Entry conditions included the use of a vortex generator to evaluate the effect of shed vortices on the AFRSI located in the area of concern.

Investigations of the 0.020-scale 88-OTS Integrated Space Shuttle Vehicle Jet-Plume Model in the NASA/Ames Research Center 11 by11-Foot Unitary Plan Wind Tunnel (IA80). Volume 1

Science.gov (United States)

Nichols, M. E.

1976-01-01

The results are documented of jet plume effects wind tunnel test of the 0.020-scale 88-OTS launch configuration space shuttle vehicle model in the 11 x 11 foot leg of the NASA/Ames Research Center Unitary Plan Wind Tunnel. This test involved cold gas main propulsion system (MPS) and solid rocket motor (SRB) plume simulations at Mach numbers from 0.6 to 1.4. Integrated vehicle surface pressure distributions, elevon and rudder hinge moments, and wing and vertical tail root bending and torsional moments due to MPS and SRB plume interactions were determined. Nozzle power conditions were controlled per pretest nozzle calibrations. Model angle of attack was varied from -4 deg to +4 deg; model angle of sideslip was varied from -4 deg to +4 deg. Reynolds number was varied for certain test conditions and configurations, with the nominal freestream total pressure being 14.69 psia. Plotted force and pressure data are presented.

Planck intermediate results. XV. A study of anomalous microwave emission in Galactic clouds

DEFF Research Database (Denmark)

Ade, P. A. R.; Aghanim, N.; Alves, Marie-Helene

2014-01-01

radiation field, G0. Modelling of this trend suggests that both radiative and collisional excitation are important for the spinning dust emission. The most significant AME regions tend to have relatively less ionized gas (free-free emission), although this could be a selection effect. The infrared excess......Anomalous microwave emission (AME) is believed to be due to electric dipole radiation from small spinning dust grains. The aim of this paper is a statistical study of the basic properties of AME regions and the environment in which they emit. We used WMAP and Planck maps, combined with ancillary...... for the AME regions. The AME regions tend to be associated with cooler dust in the range 14−20 K and an average emissivity index, βd, of +1.8, while the non-AME regions are typically warmer, at 20−27 K. In agreement with previous studies, the AME emissivity appears to decrease with increasing column density...

Combined Alcohol and Energy Drink Use: Hedonistic Motives, Adenosine, and Alcohol Dependence

Science.gov (United States)

Marczinski, Cecile A.

2014-01-01

Consumption of alcohol mixed with energy drinks (AmED) has been associated with both short and long-term risks beyond those observed with alcohol alone. AmED use has been associated with heavy episodic (binge) drinking, risky behaviors, and risk of alcohol dependence. Laboratory research has demonstrated that AmED beverages lead to greater motivation to drink versus the same amount of alcohol consumed alone. However, the reason consumers find AmED beverages particularly appealing has been unclear. A recent report by Droste and colleagues (2014) is the first study to investigate motivations related to AmED consumption and to determine which motives predict AmED consumption patterns, experience of drinking-related harms, and risk of alcohol dependence. The findings of this study significantly enhance our understanding of why AmED consumption is related to the risk of alcohol dependence and change our understanding of why consumers chose AmED beverages. The authors report that hedonistic motives strongly predicted AmED use and the harms associated with use. While intoxication-reduction motives predicted self-reported accidents and injuries, these motives did not predict AmED consumption patterns and risk of dependence. The risk of alcohol dependence may arise from repeated experiences when drinking alcohol is more pleasurable when energy drinks are consumed with the alcohol. This commentary will focus on why energy drinks might increase the rewarding properties of alcohol in social drinkers. In addition, discussion is provided explaining why more research on the neurotransmitter, adenosine, may actually inform us about the mechanisms contributing to the development of alcohol dependence. PMID:25040590

Alcohol mixed with energy drink use among u.s. 12th-grade students: prevalence, correlates, and associations with unsafe driving.

Science.gov (United States)

Martz, Meghan E; Patrick, Megan E; Schulenberg, John E

2015-05-01

The consumption of alcohol mixed with energy drinks (AmED) is a risky drinking behavior, most commonly studied using college samples. We know little about rates of AmED use and its associations with other risk behaviors, including unsafe driving, among high school students. This study examined the prevalence and correlates of AmED use among high school seniors in the United States. Nationally representative analytic samples included 6,498 12th-grade students who completed Monitoring the Future surveys in 2012 and 2013. Focal measures included AmED use, sociodemographic characteristics, academic and social factors, other substance use, and unsafe driving (i.e., tickets/warnings and accidents) after alcohol consumption. Approximately one in four students (24.8%) reported AmED use during the past 12 months. Rates of AmED use were highest among males and white students. Using multivariable logistic regression models controlling for sociodemographic characteristics, results indicate that students who cut class, spent more evenings out for fun and recreation, and reported binge drinking, marijuana use, and illicit drug use had a greater likelihood of AmED use. AmED use was also associated with greater odds of alcohol-related unsafe driving, even after controlling for sociodemographic, academic, and social factors and other substance use. AmED use among 12th-grade students is common and associated with certain sociodemographic, academic, social, and substance use factors. AmED use is also related to alcohol-related unsafe driving, which is a serious public health concern. Copyright © 2015 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

Are energy drinks unique mixers in terms of their effects on alcohol consumption and negative alcohol-related consequences?

Science.gov (United States)

Johnson, Sean J; Alford, Chris; Stewart, Karina; Verster, Joris C

2018-01-01

Previous research has suggested that consuming alcohol mixed with energy drinks (AMED) increases overall alcohol consumption. However, there is limited research examining whether energy drinks are unique in their effects when mixed with alcohol, when compared with alcohol mixed with other caffeinated mixers (AOCM). Therefore, the aim of this survey was to investigate alcohol consumption on AMED occasions, to that on other occasions when the same individuals consumed AOCM or alcohol only (AO). A UK-wide online student survey collected data on the frequency of alcohol consumption and quantity consumed, as well as the number of negative alcohol-related consequences reported on AO, AMED and AOCM occasions (N=250). Within-subjects analysis revealed that there were no significant differences in the number of alcoholic drinks consumed on a standard and a heavy drinking session between AMED and AOCM drinking occasions. However, the number of standard mixers typically consumed was significantly lower on AMED occasions compared with AOCM occasions. In addition, when consuming AMED, students reported significantly fewer days consuming 5 or more alcohol drinks, fewer days mixing drinks, and fewer days being drunk, compared with when consuming AOCM. There were no significant differences in the number of reported negative alcohol-related consequences on AMED occasions to AOCM occasions. Of importance, alcohol consumption and negative alcohol-related consequences were significantly less on both AMED and AOCM occasions compared with AO occasions. The findings that heavy alcohol consumption occurs significantly less often on AMED occasions compared with AOCM occasions is in opposition to some earlier claims implying that greatest alcohol consumption occurs with AMED. The overall greatest alcohol consumption and associated negative consequences were clearly associated with AO occasions. Negative consequences for AMED and AOCM drinking occasions were similar, suggesting that energy