WorldWideScience

Sample records for alternatives study ctas

  1. Cogeneration Technology Alternatives Study (CTAS). Volume 4: Energy conversion systems

    Science.gov (United States)

    Brown, D. H.; Gerlaugh, H. E.; Priestley, R. R.

    1980-01-01

    Industrial processes from the largest energy consuming sectors were used as a basis for matching a similar number of energy conversion systems that are considered as candidate which can be made available by the 1985 to 2000 time period. The sectors considered included food, textiles, lumber, paper, chemicals, petroleum, glass, and primary metals. The energy conversion systems included steam and gas turbines, diesels, thermionics, stirling, closed-cycle and steam injected gas turbines, and fuel cells. Fuels considered were coal, both coal and petroleum-based residual and distillate liquid fuels, and low Btu gas obtained through the on-site gasification of coal. An attempt was made to use consistent assumptions and a consistent set of ground rules specified by NASA for determining performance and cost. The advanced and commercially available cogeneration energy conversion systems studied in CTAS are fined together with their performance, capital costs, and the research and developments required to bring them to this level of performance.

  2. Energy and cost savings results for advanced technology systems from the Cogeneration Technology Alternatives Study /CTAS/

    Science.gov (United States)

    Sagerman, G. D.; Barna, G. J.; Burns, R. K.

    1979-01-01

    The Cogeneration Technology Alternatives Study (CTAS), a program undertaken to identify the most attractive advanced energy conversion systems for industrial cogeneration applications in the 1985-2000 time period, is described, and preliminary results are presented. Two cogeneration options are included in the analysis: a topping application, in which fuel is input to the energy conversion system which generates electricity and waste heat from the conversion system is used to provide heat to the process, and a bottoming application, in which fuel is burned to provide high temperature process heat and waste heat from the process is used as thermal input to the energy conversion system which generates energy. Steam turbines, open and closed cycle gas turbines, combined cycles, diesel engines, Stirling engines, phosphoric acid and molten carbonate fuel cells and thermionics are examined. Expected plant level energy savings, annual energy cost savings, and other results of the economic analysis are given, and the sensitivity of these results to the assumptions concerning fuel prices, price of purchased electricity and the potential effects of regional energy use characteristics is discussed.

  3. Energy and cost saving results for advanced technology systems from the Cogeneration Technology Alternatives Study (CTAS)

    Science.gov (United States)

    Sagerman, G. D.; Barna, G. J.; Burns, R. K.

    1979-01-01

    An overview of the organization and methodology of the Cogeneration Technology Alternatives Study is presented. The objectives of the study were to identify the most attractive advanced energy conversion systems for industrial cogeneration applications in the future and to assess the advantages of advanced technology systems compared to those systems commercially available today. Advanced systems studied include steam turbines, open and closed cycle gas turbines, combined cycles, diesel engines, Stirling engines, phosphoric acid and molten carbonate fuel cells and thermionics. Steam turbines, open cycle gas turbines, combined cycles, and diesel engines were also analyzed in versions typical of today's commercially available technology to provide a base against which to measure the advanced systems. Cogeneration applications in the major energy consuming manufacturing industries were considered. Results of the study in terms of plant level energy savings, annual energy cost savings and economic attractiveness are presented for the various energy conversion systems considered.

  4. Cogeneration Technology Alternatives Study (CTAS). Volume 3: Industrial processes

    Science.gov (United States)

    Palmer, W. B.; Gerlaugh, H. E.; Priestley, R. R.

    1980-01-01

    Cogenerating electric power and process heat in single energy conversion systems rather than separately in utility plants and in process boilers is examined in terms of cost savings. The use of various advanced energy conversion systems are examined and compared with each other and with current technology systems for their savings in fuel energy, costs, and emissions in individual plants and on a national level. About fifty industrial processes from the target energy consuming sectors were used as a basis for matching a similar number of energy conversion systems that are considered as candidate which can be made available by the 1985 to 2000 time period. The sectors considered included food, textiles, lumber, paper, chemicals, petroleum, glass, and primary metals. The energy conversion systems included steam and gas turbines, diesels, thermionics, stirling, closed cycle and steam injected gas turbines, and fuel cells. Fuels considered were coal, both coal and petroleum based residual and distillate liquid fuels, and low Btu gas obtained through the on site gasification of coal. An attempt was made to use consistent assumptions and a consistent set of ground rules specified by NASA for determining performance and cost. Data and narrative descriptions of the industrial processes are given.

  5. Cogeneration Technology Alternatives Study (CTAS). Volume 6: Computer data. Part 2: Residual-fired nocogeneration process boiler

    Science.gov (United States)

    Knightly, W. F.

    1980-01-01

    Computer generated data on the performance of the cogeneration energy conversion system are presented. Performance parameters included fuel consumption and savings, capital costs, economics, and emissions of residual fired process boilers.

  6. Cogeneration Technology Alternatives Study (CTAS). Volume 6: Computer data. Part 1: Coal-fired nocogeneration process boiler, section A

    Science.gov (United States)

    Knightly, W. F.

    1980-01-01

    About fifty industrial processes from the largest energy consuming sectors were used as a basis for matching a similar number of energy conversion systems that are considered as candidate which can be made available by the 1985 to 2000 time period. The sectors considered included food, textiles, lumber, paper, chemicals, petroleum, glass, and primary metals. The energy conversion systems included steam and gas turbines, diesels, thermionics, stirling, closed cycle and steam injected gas turbines, and fuel cells. Fuels considered were coal, both coal and petroleum based residual and distillate liquid fuels, and low Btu gas obtained through the on site gasification of coal. Computer generated reports of the fuels consumption and savings, capital costs, economics and emissions of the cogeneration energy conversion systems (ECS's) heat and power matched to the individual industrial processes are presented. National fuel and emissions savings are also reported for each ECS assuming it alone is implemented. Two nocogeneration base cases are included: coal fired and residual fired process boilers.

  7. Cogeneration Technology Alternatives Study (CTAS). Volume 6: Computer data. Part 1: Coal-fired nocogeneration process boiler, section B

    Science.gov (United States)

    Knightly, W. F.

    1980-01-01

    About fifty industrial processes from the largest energy consuming sectors were used as a basis for matching a similar number of energy conversion systems that are considered as candidate which can be made available by the 1985 to 2000 time period. The sectors considered included food, textiles, lumber, paper, chemicals, petroleum, glass, and primary metals. The energy conversion systems included steam and gas turbines, diesels, thermionics, stirling, closed cycle and steam injected gas turbines, and fuel cells. Fuels considered were coal, both coal and petroleum based residual and distillate liquid fuels, and low Btu gas obtained through the on site gasification of coal. Computer generated reports of the fuel consumption and savings, capital costs, economics and emissions of the cogeneration energy conversion systems (ECS's) heat and power matched to the individual industrial processes are presented. National fuel and emissions savings are also reported for each ECS assuming it alone is implemented. Two nocogeneration base cases are included: coal fired and residual fired process boilers.

  8. Seal design alternatives study

    International Nuclear Information System (INIS)

    This report presents the results from a study of various sealing alternatives for the WIPP sealing system. Overall, the sealing system has the purpose of reducing to the extent possible the potential for fluids (either gas or liquid) from entering or leaving the repository. The sealing system is divided into three subsystems: drift and panel seals within the repository horizon, shaft seals in each of the four shafts, and borehole seals. Alternatives to the baseline configuration for the WIPP seal system design included evaluating different geometries and schedules for seal component installations and the use of different materials for seal components. Order-of-magnitude costs for the various alternatives were prepared as part of the study. Firm recommendations are not presented, but the advantages and disadvantages of the alternatives are discussed. Technical information deficiencies are identified and studies are outlined which can provide required information

  9. Seal design alternatives study

    Energy Technology Data Exchange (ETDEWEB)

    Van Sambeek, L.L. [RE/SPEC Inc., Rapid City, SD (US); Luo, D.D.; Lin, M.S.; Ostrowski, W.; Oyenuga, D. [Parsons Brinckerhoff Quade & Douglas, Inc., San Francisco, CA (US)

    1993-06-01

    This report presents the results from a study of various sealing alternatives for the WIPP sealing system. Overall, the sealing system has the purpose of reducing to the extent possible the potential for fluids (either gas or liquid) from entering or leaving the repository. The sealing system is divided into three subsystems: drift and panel seals within the repository horizon, shaft seals in each of the four shafts, and borehole seals. Alternatives to the baseline configuration for the WIPP seal system design included evaluating different geometries and schedules for seal component installations and the use of different materials for seal components. Order-of-magnitude costs for the various alternatives were prepared as part of the study. Firm recommendations are not presented, but the advantages and disadvantages of the alternatives are discussed. Technical information deficiencies are identified and studies are outlined which can provide required information.

  10. Energy conversion alternatives study

    Science.gov (United States)

    Shure, L. T.

    1979-01-01

    Comparison of coal based energy systems is given. Study identifies and compares various advanced energy conversion systems using coal or coal derived fuels for baselaoad electric power generation. Energy Conversion Alternatives Study (ECAS) reports provede government, industry, and general public with technically consistent basis for comparison of system's options of interest for fossilfired electric-utility application.

  11. Integrating the Base of Aircraft Data (BADA) in CTAS Trajectory Synthesizer

    Science.gov (United States)

    Abramson, Michael; Ali, Kareem

    2012-01-01

    The Center-Terminal Radar Approach Control (TRACON) Automation System (CTAS), developed at NASA Ames Research Center for assisting controllers in the management and control of air traffic in the extended terminal area, supports the modeling of more than four hundred aircraft types. However, 90% of them are supported indirectly by mapping them to one of a relatively few aircraft types for which CTAS has detailed drag and engine thrust models. On the other hand, the Base of Aircraft Data (BADA), developed and maintained by Eurocontrol, supports more than 300 aircraft types, about one third of which are directly supported, i.e. they have validated performance data. All these data were made available for CTAS by integrating BADA version 3.8 into CTAS Trajectory Synthesizer (TS). Several validation tools were developed and used to validate the integrated code and to evaluate the accuracy of trajectory predictions generated using CTAS "native" and BADA Aircraft Performance Models (APM) comparing them with radar track data. Results of these comparisons indicate that the two models have different strengths and weaknesses. The BADA APM can improve the accuracy of CTAS predictions at least for some aircraft types, especially small aircraft, and for some flight phases, especially climb.

  12. Normetex Pump Alternatives Study

    Energy Technology Data Exchange (ETDEWEB)

    Clark, Elliot A.

    2013-04-25

    A mainstay pump for tritium systems, the Normetex scroll pump, is currently unavailable because the Normetex company went out of business. This pump was an all-metal scroll pump that served tritium processing facilities very well. Current tritium system operators are evaluating replacement pumps for the Normetex pump and for general used in tritium service. An all-metal equivalent alternative to the Normetex pump has not yet been identified. 1. The ideal replacement tritium pump would be hermetically sealed and contain no polymer components or oils. Polymers and oils degrade over time when they contact ionizing radiation. 2. Halogenated polymers (containing fluorine, chlorine, or both) and oils are commonly found in pumps. These materials have many properties that surpass those of hydrocarbon-based polymers and oils, including thermal stability (higher operating temperature) and better chemical resistance. Unfortunately, they are less resistant to degradation from ionizing radiation than hydrocarbon-based materials (in general). 3. Polymers and oils can form gaseous, condensable (HF, TF), liquid, and solid species when exposed to ionizing radiation. For example, halogenated polymers form HF and HCl, which are extremely corrosive upon reaction with water. If a pump containing polymers or oils must be used in a tritium system, the system must be designed to be able to process the unwanted by-products. Design features to mitigate degradation products include filters and chemical or physical traps (eg. cold traps, oil traps). 4. Polymer components can work in tritium systems, but must be replaced regularly. Polymer components performance should be monitored or be regularly tested, and regular replacement of components should be viewed as an expected normal event. A radioactive waste stream must be established to dispose of used polymer components and oil with an approved disposal plan developed based on the facility location and its regulators. Polymers have varying

  13. Orion Project: Alternate Attitude Study

    Science.gov (United States)

    Alvarez-Hernandez, A.; Miller, Stephen W.

    2009-01-01

    This slide presentation reviews the study done on alternate attitudes for the Orion project's crew exploration vehicle. The analysis focused on the thermal performance of the vehicle with the alternate attitudes. The pressure vessel heater power, other vehicle heaters and radiator sink temperatures were included in the analysis.

  14. Energy Conversion Alternatives Study (ECAS)

    Science.gov (United States)

    1977-01-01

    ECAS compared various advanced energy conversion systems that can use coal or coal-derived fuels for baseload electric power generation. It was conducted in two phases. Phase 1 consisted of parametric studies. From these results, 11 concepts were selected for further study in Phase 2. For each of the Phase 2 systems and a common set of ground rules, performance, cost, environmental intrusion, and natural resource requirements were estimated. In addition, the contractors defined the state of the associated technology, identified the advances required, prepared preliminary research and development plans, and assessed other factors that would affect the implementation of each type of powerplant. The systems studied in Phase 2 include steam systems with atmospheric- and pressurized-fluidized-bed boilers; combined cycle gas turbine/steam systems with integrated gasifiers or fired by a semiclean, coal derived fuel; a potassium/steam system with a pressurized-fluidized-bed boiler; a closed-cycle gas turbine/organic system with a high-temperature, atmospheric-fluidized-bed furnace; a direct-coal-fired, open- cycle magnetohydrodynamic/steam system; and a molten-carbonate fuel cell/steam system with an integrated gasifier. The sensitivity of the results to changes in the ground rules and the impact of uncertainties in capital cost estimates were also examined.

  15. Comparative Studies of Alternative Anaerobic Digestion Technologies

    OpenAIRE

    Inman, David C.

    2004-01-01

    Washington D.C. Water and Sewage Authority is planning to construct a new anaerobic digestion facility at its Blue Plains WWTP by 2008. The research conducted in this study is to aid the designers of this facility by evaluating alternative digestion technologies. Alternative anaerobic digestion technologies include thermophilic, acid/gas phased, and temperature phased digestion. In order to evaluate the relative merits of each, a year long study evaluated the performance of bench scale dig...

  16. Cornerstone Third Party Alternative Cost Study

    Energy Technology Data Exchange (ETDEWEB)

    Vrieling, P. Douglas [Sandia National Lab. (SNL-CA), Livermore, CA (United States)

    2013-10-15

    The attached cost analyses sheets have been developed for use in planning during the Third Party Alternative study currently underway for the Sandia CREATE project. This cost analysis builds upon the previously submitted base estimate dated June 14, 2013 and includes comparison information collected during a Market Validation exercise conducted in August/September 2013.

  17. Center-TRACON Automation System (CTAS) En Route Trajectory Predictor Requirements and Capabilities

    Science.gov (United States)

    Vivona, Robert; Cate, Karen Tung

    2013-01-01

    This requirements framework document is designed to support the capture of requirements and capabilities for state-of-the-art trajectory predictors (TPs). This framework has been developed to assist TP experts in capturing a clear, consistent, and cross-comparable set of requirements and capabilities. The goal is to capture capabilities (types of trajectories that can be built), functional requirements (including inputs and outputs), non-functional requirements (including prediction accuracy and computational performance), approaches for constraint relaxation, and input uncertainties. The sections of this framework are based on the Common Trajectory Predictor structure developed by the FAA/Eurocontrol Cooperative R&D Action Plan 16 Committee on Common Trajectory Prediction. It is assumed that the reader is familiar with the Common TP Structure.1 This initial draft is intended as a first cut capture of the En Route TS Capabilities and Requirements. As such, it contains many annotations indicating possible logic errors in the CTAS code or in the description provided. It is intended to work out the details of the annotations with NASA and to update this document at a later time.

  18. Pantex staging study near-term alternatives

    Energy Technology Data Exchange (ETDEWEB)

    Madden, M.S.; Adickes, M.D.; Hostick, C.J.; Nealey, S.M.; Smith, B.W.

    1992-12-01

    As the result of bilateral treaties to reduce the number of weapons in the nuclear stockpile, the US Department of Energy must now address the requirements for additional storage of the plutonium components (pits) from the retired weapons at Pantex until the components' final disposition. Because of the critical need to take action, Pantex has initiated two related efforts: Project Stage Right and this Staging Study. While support of Project Stage Right is a key objective of this study, the scope covers a broader range of activities and aspects of the pit staging problem. This study provides estimates of worker radiation exposures under the current scenario as well as estimated radiation exposure for workers under four alternative staging scenarios. An important objective of this study also identifies and recommends for future study other activities related to staging where radiation safety and overall efficiency can be improved.

  19. Pantex staging study near-term alternatives

    Energy Technology Data Exchange (ETDEWEB)

    Madden, M.S.; Adickes, M.D.; Hostick, C.J.; Nealey, S.M.; Smith, B.W.

    1992-12-01

    As the result of bilateral treaties to reduce the number of weapons in the nuclear stockpile, the US Department of Energy must now address the requirements for additional storage of the plutonium components (pits) from the retired weapons at Pantex until the components` final disposition. Because of the critical need to take action, Pantex has initiated two related efforts: Project Stage Right and this Staging Study. While support of Project Stage Right is a key objective of this study, the scope covers a broader range of activities and aspects of the pit staging problem. This study provides estimates of worker radiation exposures under the current scenario as well as estimated radiation exposure for workers under four alternative staging scenarios. An important objective of this study also identifies and recommends for future study other activities related to staging where radiation safety and overall efficiency can be improved.

  20. Tobacco Advertising Study, 2008/2011

    Data.gov (United States)

    U.S. Department of Health & Human Services — The California Tobacco Advertising Survey (CTAS) is a longitudinal cohort study of California stores that sell cigarettes. The data table shows the percentage of...

  1. Ironmaking Process Alternative Screening Study, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Lockwood Greene, . .

    2005-01-06

    Iron in the United States is largely produced from iron ore mined in the United States or imported from Canada or South America. The iron ore is typically smelted in Blast Furnaces that use primarily iron ore, iron concentrate pellets metallurgical coke, limestone and lime as the raw materials. Under current operating scenarios, the iron produced from these Blast Furnaces is relatively inexpensive as compared to current alternative iron sources, e.g. direct iron reduction, imported pig iron, etc. The primary problem the Blast Furnace Ironmaking approach is that many of these Blast furnaces are relatively small, as compared to the newer, larger Blast Furnaces; thus are relatively costly and inefficient to operate. An additional problem is also that supplies of high-grade metallurgical grade coke are becoming increasingly in short supply and costs are also increasing. In part this is due to the short supply and costs of high-grade metallurgical coals, but also this is due to the increasing necessity for environmental controls for coke production. After year 2003 new regulations for coke product environmental requirement will likely be promulgated. It is likely that this also will either increase the cost of high-quality coke production or will reduce the available domestic U.S. supply. Therefore, iron production in the United States utilizing the current, predominant Blast Furnace process will be more costly and would likely be curtailed due to a coke shortage. Therefore, there is a significant need to develop or extend the economic viability of Alternate Ironmaking Processes to at least partially replace current and declining blast furnace iron sources and to provide incentives for new capacity expansion. The primary conclusions of this comparative Study of Alternative Ironmaking Process scenarios are: (1) The processes with the best combined economics (CAPEX and OPEX impacts in the I.R.R. calculation) can be grouped into those Fine Ore based processes with no scrap

  2. Alternative waste forms: a comparative study

    International Nuclear Information System (INIS)

    A characterization study utilizing comparative tests has been conducted to assess product inertness of alternative waste form materials, having evaluated at this point four basic product types: sintered ceramics, glass ceramics, glass and concrete. The seven specific waste form materials studied represent simulated nuclear waste loading of 5% to 100%, processed between room temperature and 12000C and subjected to characterization tests including phase analysis, microstructure, compression testing, volatility and leach testing. Significant conclusions based upon the results obtained to date are: sintered calcine waste form PW-9 does not retain Na, Mo and Cs when leached 900C and, in fact, does not remain a solid; glass and supercalcine are alike under both hydrous and hydrothermal leach conditions with glass exhibiting a greater retention of sodium and molybdenum, supercalcine having a greater retention of cesium, and both forms approximately equal in strontium retention; volatility measurements indicate that an order of magnitude decrease in volatility occurs when a calcine waste form is incorporated in a crystalline or glassy host; glass 76-68 is superior to supercalcine SPC-5B in retention of volatiles below 11000C because of the high release of Na from SPC-5B, however, as the temperature approaches or exceeds the glass melt temperature, volatile losses of the glass equal or exceed that of SPC-5B; glass 76-68 and supercalcine SPC-5B have high compressive strengths when compared to sintered PW-9 and cement products. This is apparently due to a stronger continuum bond resulting from a glassy matrix or crystalline ingrowth over a simple mechanical agglomeration of particles

  3. Washoe Tribe Alternative Energy Feasibility Study Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, Jennifer [Washoe Tribe of NV and CA

    2014-10-01

    The Washoe Tribe of Nevada and California was awarded funding to complete the Washoe Tribe Alternative Energy Feasibility Study project. The main goal of the project was to complete an alternative energy feasibility study. This study was completed to evaluate “the potential for development of a variety of renewable energy projects and to conduct an alternative energy feasibility study that determines which alternative energy resources have the greatest economic opportunity for the Tribe, while respecting cultural and environmental values” (Baker-Tilly, 2014). The study concluded that distributed generation solar projects are the best option for renewable energy development and asset ownership for the Washoe Tribe. Concentrating solar projects, utility scale wind projects, geothermal, and biomass resource projects were also evaluated during the study and it was determined that these alternatives would not be feasible at this time.

  4. IronMaking Process Alternatives Screening Study

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2000-10-01

    This study by Lockwood Greene evaluates a number ironmaking processes. The appendices provide greater detail and further exploration of the ironmaking processes, including components, relative costs, and comparisons.

  5. Alternative Frameworks for the Study of Man.

    Science.gov (United States)

    Markova, Ivana

    1979-01-01

    Two frameworks for the study of man are discussed. The Cartesian model views man as a physical object. A dialectic framework, with the emphasis on the self, grew out of nineteenth century romanticism and reflects the theories of Hegel. Both models have had an effect on social psychology and the study of interpersonal communication. (BH)

  6. Alternative approach to study fusion barrier distribution

    International Nuclear Information System (INIS)

    Fusion reactions induced by heavy-ions (HIs) at around barrier energies, play an important role in nuclear physics since they enable to study the nuclei away from the valley of stability. On the other hand, heavy-ion collisions, at below and near barrier energies, provide an ideal opportunity to study quantum tunneling phenomena in systems with many degrees of freedom. In a simple model, a potential barrier for the relative motion between the interacting nuclei is created by the strong interplay of the repulsive Coulomb and the attractive nuclear force. It has, now, been well recognized that heavy-ion collisions at energies around the Coulomb barrier are strongly affected by the internal structure of interacting nuclei. The couplings of the relative motion to the intrinsic degrees of freedom (such as collective inelastic excitations of the colliding nuclei and/or transfer processes) replaced a single potential barrier to a number of distributed barriers, leading to the enhancement in heavy ion fusion cross sections at energies near and below the Coulomb barrier than those expected from single one-dimensional barrier

  7. Lithic studies: an alternative approach to Neolithization

    Directory of Open Access Journals (Sweden)

    Maria Gurova

    2014-12-01

    Full Text Available Most models of Neolithization of the Balkans have focused on pottery, with little attention paid to other aspects of material culture. A distinctive feature of the Early Neolithic Karanovo I culture of Bulgaria is a flint industry characterized by ‘macroblade’ technology and widespread use of ‘Balkan Flint’ in conjunction with formal toolkits. The origins of this technology and the associated raw material procurement system are still unresolved. Balkan flint also occurs in Early Neolithic contexts outside the Karanovo I culture area, notably in the southern Balkans (Turkish Thrace and in the lower Danube catchment (Carpathian Basin, Iron Gates, southern Romania and northern Bulgaria. The only securely identified outcrops of Balkan flint are in the Upper Cretaceous Mezdra Formation in the Pleven-Nikopol region of northern Bulgaria. One of the most challenging aspects of the Neolithization debate is to accommodate the evidence provided by lithic studies. Among outstanding questions are: (i was Balkan flint used by the first (‘pre-Karanovo’ Neolithic communities in Bulgaria; (ii what role did Balkan flint play in the Neolithization of Southeast Europe; (iii did access to Balkan flint result in the emergence of a new laminar technology; (iv how did the Early Neolithic Balkan flint exchange network compare to that based on obsidian, which developed in and around the Aegean Basin; and (iv what and where were the origins of the Balkan flint network and the formal tools associated with it?

  8. Alternative techniques to study characters of the genitalia in Lepidoptera.

    Science.gov (United States)

    Dias, Fernando M S; Casagrande, Mirna M; Mielke, Olaf H H

    2010-01-01

    The present note aims to describe two alternative methods for observing genitalia in Lepidoptera. The first one provides means to examine both male and female genitalia without spoiling the scales of the abdomen, preserving it attached to the thorax and aesthetically similar to an unexamined specimen. The second one provides ways of observing certain characters on the male genitalia in a non-destructive way, and does not depend on time-consuming removing and dissection of the abdomen. It is expected that the presented techniques will help on morphological studies and on identifying similar species which consistently differ in genitalic armatures.

  9. Alternative diagnoses based on CT angiography of the chest in patients with suspected pulmonary thromboembolism

    Science.gov (United States)

    Ferreira, Eleci Vaz; Gazzana, Marcelo Basso; Sarmento, Muriel Bossle; Guazzelli, Pedro Arends; Hoffmeister, Mariana Costa; Guerra, Vinicius André; Seligman, Renato; Knorst, Marli Maria

    2016-01-01

    Objective : To determine the prevalence of alternative diagnoses based on chest CT angiography (CTA) in patients with suspected pulmonary thromboembolism (PTE) who tested negative for PTE, as well as whether those alternative diagnoses had been considered prior to the CTA. Methods : This was a cross-sectional, retrospective study involving 191 adult patients undergoing CTA for suspected PTE between September of 2009 and May of 2012. Chest X-rays and CTAs were reviewed to determine whether the findings suggested an alternative diagnosis in the cases not diagnosed as PTE. Data on symptoms, risk factors, comorbidities, length of hospital stay, and mortality were collected. Results : On the basis of the CTA findings, PTE was diagnosed in 47 cases (24.6%). Among the 144 patients not diagnosed with PTE via CTA, the findings were abnormal in 120 (83.3%). Such findings were consistent with an alternative diagnosis that explained the symptoms in 75 patients (39.3%). Among those 75 cases, there were only 39 (20.4%) in which the same alterations had not been previously detected on chest X-rays. The most common alternative diagnosis, made solely on the basis of the CTA findings, was pneumonia (identified in 20 cases). Symptoms, risk factors, comorbidities, and the in-hospital mortality rate did not differ significantly between the patients with and without PTE. However, the median hospital stay was significantly longer in the patients with PTE than in those without (18.0 and 9.5 days, respectively; p = 0.001). Conclusions : Our results indicate that chest CTA is useful in cases of suspected PTE, because it can confirm the diagnosis and reveal findings consistent with an alternative diagnosis in a significant number of patients. PMID:26982039

  10. Alternative diagnoses based on CT angiography of the chest in patients with suspected pulmonary thromboembolism

    Directory of Open Access Journals (Sweden)

    Eleci Vaz Ferreira

    2016-02-01

    Full Text Available Objective : To determine the prevalence of alternative diagnoses based on chest CT angiography (CTA in patients with suspected pulmonary thromboembolism (PTE who tested negative for PTE, as well as whether those alternative diagnoses had been considered prior to the CTA. Methods : This was a cross-sectional, retrospective study involving 191 adult patients undergoing CTA for suspected PTE between September of 2009 and May of 2012. Chest X-rays and CTAs were reviewed to determine whether the findings suggested an alternative diagnosis in the cases not diagnosed as PTE. Data on symptoms, risk factors, comorbidities, length of hospital stay, and mortality were collected. Results : On the basis of the CTA findings, PTE was diagnosed in 47 cases (24.6%. Among the 144 patients not diagnosed with PTE via CTA, the findings were abnormal in 120 (83.3%. Such findings were consistent with an alternative diagnosis that explained the symptoms in 75 patients (39.3%. Among those 75 cases, there were only 39 (20.4% in which the same alterations had not been previously detected on chest X-rays. The most common alternative diagnosis, made solely on the basis of the CTA findings, was pneumonia (identified in 20 cases. Symptoms, risk factors, comorbidities, and the in-hospital mortality rate did not differ significantly between the patients with and without PTE. However, the median hospital stay was significantly longer in the patients with PTE than in those without (18.0 and 9.5 days, respectively; p = 0.001. Conclusions : Our results indicate that chest CTA is useful in cases of suspected PTE, because it can confirm the diagnosis and reveal findings consistent with an alternative diagnosis in a significant number of patients.

  11. Alternative diagnoses based on CT angiography of the chest in patients with suspected pulmonary thromboembolism

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Eleci Vaz; Gazzana, Marcelo Basso; Seligman, Renato; Knorst, Marli Maria, E-mail: mknorst@gmail.com [Hospital de Clinicas de Porto Alegre, Porto Alegre, RS (Brazil); Guerra, Vinicius Andre [Universidade Federal do Rio Grande do Sul (UFRS), Porto Alegre, RS (Brazil). Faculdade de Medicina. Programa de Pos-Graduacao em Ciencias Pneumologicas; Sarmento, Muriel Bossle; Guazzelli, Pedro Arends; Hoffmeister, Mariana Costa [Universidade Federal do Rio Grande do Sul (UFRS), Porto Alegre (Brazil). Faculdade de Medicina

    2016-01-15

    Objective: To determine the prevalence of alternative diagnoses based on chest CT angiography (CTA) in patients with suspected pulmonary thromboembolism (PTE) who tested negative for PTE, as well as whether those alternative diagnoses had been considered prior to the CTA. Methods: This was a cross-sectional, retrospective study involving 191 adult patients undergoing CTA for suspected PTE between September of 2009 and May of 2012. Chest X-rays and CTAs were reviewed to determine whether the findings suggested an alternative diagnosis in the cases not diagnosed as PTE. Data on symptoms, risk factors, comorbidities, length of hospital stay, and mortality were collected. Results: On the basis of the CTA findings, PTE was diagnosed in 47 cases (24.6%). Among the 144 patients not diagnosed with PTE via CTA, the findings were abnormal in 120 (83.3%). Such findings were consistent with an alternative diagnosis that explained the symptoms in 75 patients (39.3%). Among those 75 cases, there were only 39 (20.4%) in which the same alterations had not been previously detected on chest X-rays. The most common alternative diagnosis, made solely on the basis of the CTA findings, was pneumonia (identified in 20 cases). Symptoms, risk factors, comorbidities, and the in-hospital mortality rate did not differ significantly between the patients with and without PTE. However, the median hospital stay was significantly longer in the patients with PTE than in those without (18.0 and 9.5 days, respectively; p = 0.001). Conclusions: Our results indicate that chest CTA is useful in cases of suspected PTE, because it can confirm the diagnosis and reveal findings consistent with an alternative diagnosis in a significant number of patients. (author)

  12. GÉNERO Y CAPACIDADES DIRECTIVAS EN COOPERATIVAS DE TRABAJO ASOCIADO. ESTUDIO EXPLORATORIO EN CTAS VALENCIANAS / GENDER AND MANAGER’S CAPABILITIES IN WORK-COOPERATIVE FIRMS. EXPLORATORY RESEARCH IN COOPS IN VALENCIA (SPAIN

    Directory of Open Access Journals (Sweden)

    Waldo ORELLANA ZAMBRANO

    2011-05-01

    Full Text Available Son numerosas las investigaciones que desde hace más de dos décadas han investigado posibles influencias de género en el comportamiento en la empresa y en los estilos de dirección. Sin embargo, en el análisis no se han contemplado los aspectos institucionales y organizativos, que juegan un papel relevante en el comportamiento y en el trabajo de los directivos. Atendiendo a lo anterior, este trabajo muestra las implicaciones organizativas que tiene la forma institucional Cooperativa de trabajo asociado (CTA y cómo afectan al trabajo directivo. Asimismo, y desde una perspectiva de género, se investigan en CTAs valencianas las capacidades directivas vinculadas a diferencias de género. Los resultados obtenidos sugieren que la naturaleza del trabajo que realizan las directivas (mujeres, así como su visión del trabajo directivo responde a un estilo directivo contemporáneo, y tienen un mayor “encaje” con el contexto organizativo de la CTA caracterizado por relaciones entre iguales. / In the last two decades, much research has been done regarding gender differences and leadership styles. This paper presents some of the organizational implications of cooperative firms (Coops and how their characteristics affect the leadership style of managers. Also, from a gender perspective, we study the management style associated with gender differences in Coops in Valencia (Spain. The results suggest that the nature of the work done by women managers, and their vision of management, responds to a more contemporary leadership style, and fits better in the organizational context of coops, which are characterized by equal relations.

  13. Cogeneration technology alternatives study. Volume 6: Computer data

    Science.gov (United States)

    1980-01-01

    The potential technical capabilities of energy conversion systems in the 1985 - 2000 time period were defined with emphasis on systems using coal, coal-derived fuels or alternate fuels. Industrial process data developed for the large energy consuming industries serve as a framework for the cogeneration applications. Ground rules for the study were established and other necessary equipment (balance-of-plant) was defined. This combination of technical information, energy conversion system data ground rules, industrial process information and balance-of-plant characteristics was analyzed to evaluate energy consumption, capital and operating costs and emissions. Data in the form of computer printouts developed for 3000 energy conversion system-industrial process combinations are presented.

  14. A study on the characteristics of alternative coolants

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Ji Young; Kim, B. H.; Kim, T. J.; Jeong, K. C.; Choi, Y. D.; Choi, J. H.; Hwang, S. T

    2000-12-01

    The role of the coolant in liquid metal fast breeder reactor is very important for reasons of system safety. Recently, it has revealed that lead and lead-bismuth alloy show good safety characteristics as a fast reactor coolant compared to the sodium, such as low chemical activity, high boiling temperature and more negative void coefficient. So many countries take interest in these metals. The objectives of this project are to study the characteristics of heavy liquid metals(lead, lead-bismuth alloy) and to provide valuble information useful for the estimate the possibilities of its as the alternative coolant materials. An intensive research was performed into the global development status, basic properties, safety assurance methods, and direction of research in the futures and so on.

  15. The study, design and simulation of a free piston Stirling engine linear alternatorThe study, design and simulation of a free piston Stirling engine linear alternator

    Directory of Open Access Journals (Sweden)

    Teodora Susana Oros

    2014-12-01

    Full Text Available This paper presents a study, design and simulation of a Free Piston Stirling Engine Linear Alternator. There are presented the main steps of the magnetic and electric calculations for a permanent magnet linear alternator of fixed coil and moving magnets type. Finally, a detailed thermal, mechanical and electrical model for a Stirling engine linear alternator have been made in SIMULINK simulation program. The linear alternator simulation model uses a controllable DC voltage which simulates the linear alternator combined with a rectifier, a variable load and a DC-DC converter, which compensates for the variable nature of Stirling engine operation, and ensures a constant voltage output regardless of the load.

  16. A study of alternative splicing in the pig

    DEFF Research Database (Denmark)

    Hillig, Ann-Britt Nygaard; Cirera Salicio, Susanna; Gilchrist, Michael J.;

    2010-01-01

    BACKGROUND: Since at least half of the genes in mammalian genomes are subjected to alternative splicing, alternative pre-mRNA splicing plays an important contribution to the complexity of the mammalian proteome. Expressed sequence tags (ESTs) provide evidence of a great number of possible...... and mouse, we find putative splice variants in about 30% of the contigs with more than 50 ESTs. Based on the criteria that a minimum of two EST sequences confirmed each splice event, a list of 100 genes with the most distinct tissue-specific alternative splice events was generated from the list...... of candidates. To confirm the tissue specificity of the splice events, 10 genes with functional annotation were randomly selected from which 16 individual splice events were chosen for experimental verification by quantitative PCR (qPCR). Six genes were shown to have tissue specific alternatively spliced...

  17. Alternative Fuels for Marine and Inland Waterways: An exploratory study

    OpenAIRE

    MOIRANGTHEM KAMALJIT

    2016-01-01

    Alternative fuels for marine transport can play a crucial role in decarbonising the shipping sector and ultimately contribute towards climate change goals. Market penetration by alternative fuels have already begun with ship builders, engine manufacturers and classification bodies by introducing greener ships running on cleaner fuels. This can be attributed in large part to the MARPOL (International Convention for the Prevention of Pollution from Ships) regulations in place since the 1970s an...

  18. USE OF NON-MAMMALIAN ALTERNATIVE MODELS FOR NEUROTOXICOLOGICAL STUDY

    OpenAIRE

    Peterson, Randall T.; Nass, Richard; Boyd, Windy A; Jonathan H Freedman; Dong, Ke; Narahashi, Toshio

    2008-01-01

    The field of neurotoxicology needs to satisfy two opposing demands: the testing of a growing list of chemicals, and resource limitations and ethical concerns associated with testing using traditional mammalian species. National and international government agencies have defined a need to reduce, refine or replace mammalian species in toxicological testing with alternative testing methods and non-mammalian models. Toxicological assays using alternative animal models may relieve some of this pr...

  19. Advanced transportation system studies. Alternate propulsion subsystem concepts: Propulsion database

    Science.gov (United States)

    Levack, Daniel

    1993-01-01

    The Advanced Transportation System Studies alternate propulsion subsystem concepts propulsion database interim report is presented. The objective of the database development task is to produce a propulsion database which is easy to use and modify while also being comprehensive in the level of detail available. The database is to be available on the Macintosh computer system. The task is to extend across all three years of the contract. Consequently, a significant fraction of the effort in this first year of the task was devoted to the development of the database structure to ensure a robust base for the following years' efforts. Nonetheless, significant point design propulsion system descriptions and parametric models were also produced. Each of the two propulsion databases, parametric propulsion database and propulsion system database, are described. The descriptions include a user's guide to each code, write-ups for models used, and sample output. The parametric database has models for LOX/H2 and LOX/RP liquid engines, solid rocket boosters using three different propellants, a hybrid rocket booster, and a NERVA derived nuclear thermal rocket engine.

  20. WRAP Module 1 sampling strategy and waste characterization alternatives study

    International Nuclear Information System (INIS)

    The Waste Receiving and Processing Module 1 Facility is designed to examine, process, certify, and ship drums and boxes of solid wastes that have a surface dose equivalent of less than 200 mrem/h. These wastes will include low-level and transuranic wastes that are retrievably stored in the 200 Area burial grounds and facilities in addition to newly generated wastes. Certification of retrievably stored wastes processing in WRAP 1 is required to meet the waste acceptance criteria for onsite treatment and disposal of low-level waste and mixed low-level waste and the Waste Isolation Pilot Plant Waste Acceptance Criteria for the disposal of TRU waste. In addition, these wastes will need to be certified for packaging in TRUPACT-II shipping containers. Characterization of the retrievably stored waste is needed to support the certification process. Characterization data will be obtained from historical records, process knowledge, nondestructive examination nondestructive assay, visual inspection of the waste, head-gas sampling, and analysis of samples taken from the waste containers. Sample characterization refers to the method or methods that are used to test waste samples for specific analytes. The focus of this study is the sample characterization needed to accurately identify the hazardous and radioactive constituents present in the retrieved wastes that will be processed in WRAP 1. In addition, some sampling and characterization will be required to support NDA calculations and to provide an over-check for the characterization of newly generated wastes. This study results in the baseline definition of WRAP 1 sampling and analysis requirements and identifies alternative methods to meet these requirements in an efficient and economical manner

  1. WRAP Module 1 sampling strategy and waste characterization alternatives study

    Energy Technology Data Exchange (ETDEWEB)

    Bergeson, C.L.

    1994-09-30

    The Waste Receiving and Processing Module 1 Facility is designed to examine, process, certify, and ship drums and boxes of solid wastes that have a surface dose equivalent of less than 200 mrem/h. These wastes will include low-level and transuranic wastes that are retrievably stored in the 200 Area burial grounds and facilities in addition to newly generated wastes. Certification of retrievably stored wastes processing in WRAP 1 is required to meet the waste acceptance criteria for onsite treatment and disposal of low-level waste and mixed low-level waste and the Waste Isolation Pilot Plant Waste Acceptance Criteria for the disposal of TRU waste. In addition, these wastes will need to be certified for packaging in TRUPACT-II shipping containers. Characterization of the retrievably stored waste is needed to support the certification process. Characterization data will be obtained from historical records, process knowledge, nondestructive examination nondestructive assay, visual inspection of the waste, head-gas sampling, and analysis of samples taken from the waste containers. Sample characterization refers to the method or methods that are used to test waste samples for specific analytes. The focus of this study is the sample characterization needed to accurately identify the hazardous and radioactive constituents present in the retrieved wastes that will be processed in WRAP 1. In addition, some sampling and characterization will be required to support NDA calculations and to provide an over-check for the characterization of newly generated wastes. This study results in the baseline definition of WRAP 1 sampling and analysis requirements and identifies alternative methods to meet these requirements in an efficient and economical manner.

  2. System study of alternative waste management techniques: Final report

    International Nuclear Information System (INIS)

    This report summarizes the important results achieved in conjunction with the Research and Development Priority ''Alternative Waste Management Techniques'' sponsored by the Federal Ministry of Research and Technology from 1981 to 1984. The subject of these studies was solely ''direct disposal'' of spent fuel elements. For this purpose a reference concept was selected from a variety of possible processes and engineered in detailed form by firms in the nuclear industry. Those who worked on the engineering concepts consider this waste management method technically feasible. Several disposal casks have been fabricated. The basic licensability of direct disposal can be evaluated on the basis of the documentation developed by the companies. The direct disposal method was compared with the ''integrated waste management concept'' using reference fuel cycles with respect to the following criteria: radiological safety and nuclear material safeguards and, in addition, economic and energy-policy aspects. It was found that with respect to radiological safety, including the long-term safety of the final repository, there are no significant differences between the two fuel cycles with and without reprocessing. With respect to the nuclear material safeguards of a final repository containing spent fuel elements, there are still a number of unanswered questions. From an economic standpoint, direct disposal will be more economical in the foreseeable future than integrated waste management. Quantification of the effects of one or the other waste management method on the national economy is not necessarily possible. Reprocessing is supported primarily by technological and energy-policy considerations. On the basis of the results, the conclusion is reached that reprocessing should be pursued further, but that at the same time direct disposal should be developed to the point of practical maturity

  3. Alternative material study for heat assisted magnetic recording transducer application

    Science.gov (United States)

    Xu, B. X.; Cen, Z. H.; Hu, J. F.; Tsai, J. W. H.

    2015-05-01

    In heat assisted magnetic recording (HAMR), optical near field transducer (NFT) is a key component. Au is currently used as NFT material because of its strong surface plasmon effect. Due to the soft property of Au material, reliability of Au NFT becomes a key issue for realizing HAMR production. In this paper, the possibility of alternative materials, including transition metal nitrides (TMNs) and transparent conducting oxides (TCOs) to replace Au is studied. The results show that all of the listed TMN and TCO materials can meet the mechanical requirements at room temperature in terms of hardness and thermal expansion. An optical model, which includes optical waveguide, NFT and FePt media, is used to simulate NFT performances. The results indicate that the resonant wavelengths for NFT with TCO materials are longer than 1500 nm, which is not suitable for HAMR application. TMN materials are suitable for NFT application at wavelength band of around 800 nm. But the NFT efficiency is very low. ZrN is the best material among TMN materials and the efficiency of ZrN NFT is only 13% of the Au NFT's efficiency. Reducing refractive index (n) and increasing extinction coefficient (k) will both lead to efficiency increase. Increasing k contributes more in the efficiency increase, while reducing n has a relatively low NFT absorption. For materials with the same figure of merit, the NFT with larger k material has higher efficiency. Doping materials to increase the material conduction electron density and growing film with larger size grain may be the way to increase k and reduce n.

  4. Alternate Communications Spectrum Study (ACSS) for Aviation Data Links (ADL)

    Science.gov (United States)

    Matolak, David W.

    2003-01-01

    The aim of the work was to identify the key factors involved in the use of alternate spectrum in various bands for a future integrated CNS data link. The study focused on systems and spectral bands that can deliver VDL-or-higher data rates in a two-way communication setting (including air-ground, ground-air, and air-air modes of operation), with multiple platforms (aircraft) operating in the same local environment. We begin with a review of the initial task list, and the final task list. The final task list contained a focus upon spectral availability and related systems that could be affected by the deployment of a new aviation data link (ADL) system. Most of this addresses the lower few layers of the communications protocol stack. A brief review of current related efforts in the aeronautical community is then provided, in which we describe several systems and programs of interest. Participation in some of these efforts is recommended. We also delineate several of the advantages and disadvantages of these system/efforts, in view of anticipated requirements of a new ADL. Desired attributes of a new ADL system are then discussed, and a connection with existing systems is made. The need to consider a wider set of alternative systems and technologies is described, and the beneficial aspects of a particular transmission technique- spread spectrum-are discussed. We then discuss in more detail several potential spectral regions, in terms of propagation conditions, available technology, spectrum availability, and waveform selection. Some comments on the need for standardization are also provided. We note that none of the existing systems described will likely meet the full range of desired features of a new ADL, but that several systems and spectral regions offer promise in terms of one or more characteristics. A system design and analysis approach is then provided. In this, we again focus on the lower few layers of the protocol stack, and aim to capture the main features

  5. Alternative Assessment: Implications for Social Studies. ERIC Digest.

    Science.gov (United States)

    Nickell, Pat

    Alternative forms of evaluating student progress are changing testing or assessment in U.S. schools. From the teacher-made to the standardized test, the familiar over-emphasis on multiple-choice items is giving way to expanded generative formats in which students are called upon to demonstrate mastery through applications in which they use complex…

  6. Study on Alternative Cargo Launch Options from the Lunar Surface

    Energy Technology Data Exchange (ETDEWEB)

    Cheryl A. Blomberg; Zamir A. Zulkefli; Spencer W. Rich; Steven D. Howe

    2013-07-01

    In the future, there will be a need for constant cargo launches from Earth to Mars in order to build, and then sustain, a Martian base. Currently, chemical rockets are used for space launches. These are expensive and heavy due to the amount of necessary propellant. Nuclear thermal rockets (NTRs) are the next step in rocket design. Another alternative is to create a launcher on the lunar surface that uses magnetic levitation to launch cargo to Mars in order to minimize the amount of necessary propellant per mission. This paper investigates using nuclear power for six different cargo launching alternatives, as well as the orbital mechanics involved in launching cargo to a Martian base from the moon. Each alternative is compared to the other alternative launchers, as well as compared to using an NTR instead. This comparison is done on the basis of mass that must be shipped from Earth, the amount of necessary propellant, and the number of equivalent NTR launches. Of the options, a lunar coil launcher had a ship mass that is 12.7% less than the next best option and 17 NTR equivalent launches, making it the best of the presented six options.

  7. Sodium-Bearing Waste Treatment Alternatives Implementation Study

    Energy Technology Data Exchange (ETDEWEB)

    Charles M. Barnes; James B. Bosley; Clifford W. Olsen

    2004-07-01

    The purpose of this document is to discuss issues related to the implementation of each of the five down-selected INEEL/INTEC radioactive liquid waste (sodium-bearing waste - SBW) treatment alternatives and summarize information in three main areas of concern: process/technical, environmental permitting, and schedule. Major implementation options for each treatment alternative are also identified and briefly discussed. This report may touch upon, but purposely does not address in detail, issues that are programmatic in nature. Examples of these include how the SBW will be classified with respect to the Nuclear Waste Policy Act (NWPA), status of Waste Isolation Pilot Plant (WIPP) permits and waste storage availability, available funding for implementation, stakeholder issues, and State of Idaho Settlement Agreement milestones. It is assumed in this report that the SBW would be classified as a transuranic (TRU) waste suitable for disposal at WIPP, located in New Mexico, after appropriate treatment to meet transportation requirements and waste acceptance criteria (WAC).

  8. NGOs and GMOs: a case study in alternative science communication:

    OpenAIRE

    Maeseele, Pieter

    2009-01-01

    This article seeks to understand how and why we find local NGOs performing a role as alternative science communicators in the social conflict concerning agricultural biotechnology. First, a literature review points out that in the face of modernisation risks techno-scientific development has become contradictory, an evolution exemplified as well as driven by interdisciplinary antagonisms. This creates opportunities for a scientifi cally supported public critique of science and technology by n...

  9. ALTERNATIVE AND ENHANCED CHEMICAL CLEANING: CORROSION STUDIES RESULTS: FY2010

    Energy Technology Data Exchange (ETDEWEB)

    Wiersma, B.

    2010-09-29

    Due to the need to close High Level Waste storage tanks, chemical cleaning methods are needed for the removal of sludge heel materials remaining at the completion of mechanical tank cleaning efforts. Oxalic acid is considered the preferred cleaning reagent for heel dissolution of iron-based sludge. However, the large quantity of chemical reagents added to the tank farm from oxalic acid based cleaning has significant downstream impacts. Optimization of the oxalic acid cleaning process can potentially reduce the downstream impacts from chemical cleaning. To optimize oxalic acid usage, a detailed understanding of the chemistry of oxalic acid based sludge dissolution is required. Additionally, other acidic systems may be required for specific waste components that have low solubility in oxalic acid, and as a means to reduce oxalic acid usage in general. Electrochemical corrosion studies were conducted with 1 wt. % oxalic acid at mineral acid concentrations above and below the optimal conditions for this oxalic acid concentration. Testing environments included pure reagents, pure iron and aluminum phases, and sludge simulants. Mineral acid concentrations greater than 0.2 M and temperatures greater than 50 C result in unacceptably high corrosion rates. Results showed that manageable corrosion rates of carbon steel can be achieved at dilute mineral acid concentrations (i.e. less than 0.2 M) and low temperatures based on the contact times involved. Therefore, it is recommended that future dissolution and corrosion testing be performed with a dilute mineral acid and a less concentrated oxalic acid (e.g., 0.5 wt.%) that still promotes optimal dissolution. This recommendation requires the processing of greater water volumes than those for the baseline process during heel dissolution, but allows for minimization of oxalic acid additions. The following conclusions can be drawn from the test results: (1) In both nitric and sulfuric acid based reagents, the low temperature and

  10. Greenfield Alternative Study LEU-Mo Fuel Fabrication Facility

    Energy Technology Data Exchange (ETDEWEB)

    Washington Division of URS

    2008-07-01

    This report provides the initial “first look” of the design of the Greenfield Alternative of the Fuel Fabrication Capability (FFC); a facility to be built at a Greenfield DOE National Laboratory site. The FFC is designed to fabricate LEU-Mo monolithic fuel for the 5 US High Performance Research Reactors (HPRRs). This report provides a pre-conceptual design of the site, facility, process and equipment systems of the FFC; along with a preliminary hazards evaluation, risk assessment as well as the ROM cost and schedule estimate.

  11. Using Biofuel Tracers to Study Alternative Combustion Regimes

    Energy Technology Data Exchange (ETDEWEB)

    Mack, J H; Flowers, D L; Buchholz, B A; Dibble, R W

    2006-02-14

    Interest in the use of alternative fuels and combustion regimes is increasing as the price of petroleum climbs. The inherently higher efficiency of Diesel engines has led to increased adoption of Diesels in Europe, capturing approximately 40% of the new passenger car market. Unfortunately, lower CO{sub 2} emissions are countered with higher nitrogen oxides (NOx) and particulate matter (PM) emissions, and higher noise. Noise and PM have traditionally been the obstacles toward consumer acceptance of Diesel passenger cars in North America, while NOx (a key component in photochemical smog) has been more of an engineering challenge. Diesels are lean burning (combustion with excess oxygen) and reducing NOx to N2 in an oxygen rich environment is difficult. Adding oxygenated compounds to the fuel helps reduce PM emissions, but relying on fuel alone to reduce PM is unrealistic. Keeping peak combustion temperature below 1700 K prevents NOx formation. Altering the combustion regime to burn at temperatures below the NOx threshold and accept a wide variety of fuels seems like a promising alternative for future engines. Homogeneous Charge Compression Ignition (HCCI) is a possible solution. Fuel and air are well mixed prior to intake into a cylinder (homogeneous charge) and ignition occurs by compression of the fuel-air mixture by the piston. HCCI is rapid and relatively cool, producing little NOx and PM. Unfortunately, it is hard to control since HCCI is initiated by temperature and pressure instead of a spark or direct fuel injection. We investigate biofuel HCCI combustion, and use intrinsically labeled biofuels as tracers of HCCI combustion. Data from tracer experiments are used to validate combustion modeling.

  12. Alternative kynurenic acid synthesis routes studied in the rat cerebellum

    Directory of Open Access Journals (Sweden)

    Tonali eBlanco Ayala

    2015-05-01

    Full Text Available Kynurenic acid (KYNA, an astrocyte-derived, endogenous antagonist of α7 nicotinic acetylcholine and excitatory amino acid receptors, regulates glutamatergic, GABAergic, cholinergic and dopaminergic neurotransmission in several regions of the rodent brain. Synthesis of KYNA in the brain and elsewhere is generally attributed to the enzymatic conversion of L-kynurenine (L-KYN by kynurenine aminotransferases (KATs. However, alternative routes, including KYNA formation from D-kynurenine (D-KYN by D-amino acid oxidase (DAAO and the direct transformation of kynurenine to KYNA by reactive oxygen species (ROS, have been demonstrated in the rat brain. Using the rat cerebellum, a region of low KAT activity and high DAAO activity, the present experiments were designed to examine KYNA production from L-KYN or D-KYN by KAT and DAAO, respectively, and to investigate the effect of ROS on KYNA synthesis. In chemical combinatorial systems, both L-KYN and D-KYN interacted directly with peroxynitrite (ONOO- and hydroxyl radicals (OH•, resulting in the formation of KYNA. In tissue homogenates, the non-specific KAT inhibitor aminooxyacetic acid (AOAA; 1 mM reduced KYNA production from L-KYN and D-KYN by 85.1 ± 1.7% and 27.1 ± 4.5%, respectively. Addition of DAAO inhibitors (benzoic acid, kojic acid or 3-methylpyrazole-5-carboxylic acid; 5 µM each attenuated KYNA formation from L-KYN and D-KYN by ~35% and ~66%, respectively. ONOO- (25 µM potentiated KYNA production from both L-KYN and D-KYN, and these effects were reduced by DAAO inhibition. AOAA attenuated KYNA production from L-KYN + ONOO- but not from D-KYN + ONOO-. In vivo, extracellular KYNA levels increased rapidly after perfusion of ONOO- and, more prominently, after subsequent perfusion with L-KYN or D-KYN (100 µM. Taken together, these results suggest that different mechanisms are involved in KYNA production in the rat cerebellum, and that, specifically, DAAO and ROS can function as alternative routes

  13. Study of Temperature Gradient in Burning of Alternative Engine Fuels

    Directory of Open Access Journals (Sweden)

    M. S. Assad

    2008-01-01

    Full Text Available The paper gives an approximate method for calculation of the temperature at a final stage of fuel-air mixture burning in a closed vessel that is a combustion chamber of the internal combustion engine (ICE. The paper contains calculation of temperature values for various fuel-air mixtures, shows nature of temperature changes and presents analysis of combustion product temperature behaviour modification and analyzed the behaviour in accordance with an initial pressure in the chamber. The paper reveals the fact that a combustion temperature is increasing for all mixtures when an initial pressure in combustion chamber is increased. The hydrogen-air mixture has the highest combustion temperature among investigated mixtures and products of propane conversion have the lowest one.The Maxe-effect has been investigated in combustion of hydrogen-air mixture and design formulaes have been obtained. Calculation of temperature difference of the first and last portions of combustion products has been made with due account of the Maxe-effect.The proposed approximate method for calculation of temperatures indices in the various zones of combustion chamber in view of the Mach effect makes it possible to forecast thermodynamic nature of combustion process while using alternative engine fuels for internal combustion engine.

  14. Alternative Policy Study: Environment and energy in Europe and Central Asia 1990-2010. Energy-related environmental impacts of policy scenarios GEO-2000 alternative policy study

    NARCIS (Netherlands)

    Vuuren DP van; Bakkes JA; United Nations Environment; MNV

    2000-01-01

    The GEO-2000 study into alternative policy options for Europe and Central Asia focuses on energy use as an important driver for environmental problems across the region. The problems analyzed are climate change, acidification, summer smog, urban air pollution and risks of reactor accidents associate

  15. Critical Studies: A Trojan Horse for an Alternative Cultural Agenda?

    Science.gov (United States)

    Swift, John

    1993-01-01

    Asserts that the introduction of the term "critical studies" to British art education reflects art educators' views that the practice of art alone is insufficient to gain a full experience and coincides with a political will to return to traditional forms of content and knowledge. (CFR)

  16. Comparative study of Waste Isolation Pilot Plant (WIPP) transportation alternatives

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    WIPP transportation studies in the Final Supplement Environmental Impact Statement for WIPP are the baseline for this report. In an attempt to present the most current analysis, this study incorporates the most relevant data available. The following three transportation options are evaluated for the Disposal Phase, which is assumed to be 20 years: Truck shipments, consisting of a tractor and trailer, with three TRUPACT-IIs or one RH-72B; Regular commercial train shipments consisting of up to three railcars carrying up to 18 TRUPACT-IIs or up to six RH-72Bs; Dedicated train shipments consisting of a locomotive, an idle car, railcars carrying 18 TRUPACT-IIs or six RH-72Bs, another idle car, and a caboose or passenger car with an emergency response specialist. No other cargo is carried. This report includes: A consideration of occupational and public risks and exposures, and other environmental impacts; A consideration of emergency response capabilities; and An extimation of comparative costs.

  17. Comparative study of Waste Isolation Pilot Plant (WIPP) transportation alternatives

    International Nuclear Information System (INIS)

    WIPP transportation studies in the Final Supplement Environmental Impact Statement for WIPP are the baseline for this report. In an attempt to present the most current analysis, this study incorporates the most relevant data available. The following three transportation options are evaluated for the Disposal Phase, which is assumed to be 20 years: Truck shipments, consisting of a tractor and trailer, with three TRUPACT-IIs or one RH-72B; Regular commercial train shipments consisting of up to three railcars carrying up to 18 TRUPACT-IIs or up to six RH-72Bs; Dedicated train shipments consisting of a locomotive, an idle car, railcars carrying 18 TRUPACT-IIs or six RH-72Bs, another idle car, and a caboose or passenger car with an emergency response specialist. No other cargo is carried. This report includes: A consideration of occupational and public risks and exposures, and other environmental impacts; A consideration of emergency response capabilities; and An extimation of comparative costs

  18. Systems study 'Alternative Entsorgung'. Final report. Technical annex 23

    International Nuclear Information System (INIS)

    Reprocessing is not sensible for a number of certain spent fuel elements. From this point of view, it is necessary to develop a concept which takes into account the final storage of vitrified fission products and also fuel elements which are not processed. The aim of the mixed fuel processing concept is to design a method of treatment, which provides externally identical final storage barrels for both ways of fuel disposal and which provides associated standardized handling equipment. The study shows a way which provides for the packing of processed spent fuel elements in moulds with the external dimensions of the HAW mould and which makes it possible to store these fuel element final storage moulds together with HAW moulds in boreholes. (orig./HP)

  19. Study On Decision-Making for Cafe Management Alternatives

    Directory of Open Access Journals (Sweden)

    Cheng-I Hou

    2013-12-01

    Full Text Available In recent years, many new cafés have emerged onto t he market. Other than view cafés, beautiful cafés t hat seem as if they came from Paris or New York have gr adually appeared in leisure and quiet residential areas, in alleyways, in peripheral areas, and in lo cal commercial areas. In particular, leisure is tre ndy at present, and modern restaurants innovate in terms o f their food, leisure, and consumption. Unlike traditional restaurants, they are able to develop i nto cafés with unique styles to attract consumers. Even though not all of these new cafés are successful, a s cafés are an industry that is at the forefront of fashion, many individuals who dream of entrepreneurship woul d want to open a café. However, as there are many types of cafés on the market, what type and style o f cafés are the most suitable? An overview of cafés in Taiwan shows that each café offer unique services a nd functions to attract consumers, which is the key to sustainable operations of cafés. Therefore, this st udy explores the decisions of companies when choosi ng the style for their cafés. This study uses the anal ytical hierarchy process (AHP to explore the selec tion of café styles, in order to provide references for caf é operators to achieve successful and sustainable operations. Based on literature review, expert inte rviews, and AHP, this study intends to provide usef ul results to the operators of cafés.

  20. Numerical Studies On Bubble Pump With Alternate Working Fluids

    Directory of Open Access Journals (Sweden)

    L. Bruno Augustin

    2013-10-01

    Full Text Available The importance of energy conservation in the context of growing global population and dwindling fossil fuel resources cannot be overemphasized. Energy can be conserved by using it more efficiently. The energy spent for an application should be of the correct amount and type. It would make more sense to spend heat energy for heating rather than the high grade electricity as most of the electric power in the world is generated from driving heat engines, for which heat is supplied from the combustion of fossil fuels. At the same time, depletion of these conventional resources also poses a serious problem in meeting energy requirements. In this paper, the bubble pump, which is an integral part of diffusion- absorption refrigeration system, has been investigated numerically .A thermally driven bubble pump, which can be powered by solar thermal energy, is used to lift the liquid. The bubble pump runs on solar energy and reduces the amount of energy spent by replacing the compressor in conventional vapour absorption refrigeration system. As a result of the absence of any mechanical moving part, the refrigerator is silent and very reliable in addition to an economical and environmental friendly device. The concept of such a pump is already in existence but optimization studies are yet to be extensively investigated. This paper deals with the comparison of various parameters of the bubble pump using water and Nonane as the working fluid. Numerical simulation of the bubble pump is carried out using simple numerical equations which assume slug flow in the bubble pump. The mass flow rate, the sensible heating time and position of heating element are varied and the effect it has on diameter of the pipe, pumping ratio and the heat required is studied for both the working fluids

  1. An ornithological study of alternate gas pipeline routes in Alaska, Yukon Territory and the Northwest Territories

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The study was an attempt to describe and estimate the numbers of species and relative densities of birds along the two alternate pipeline routes, and to arrive at...

  2. ALTERNATIVE AND ENHANCED CHEMICAL CLEANING: BASIC STUDIES RESULTS FY2010

    Energy Technology Data Exchange (ETDEWEB)

    King, W.; Hay, M.

    2011-01-24

    In an effort to develop and optimize chemical cleaning methods for the removal of sludge heels from High Level Waste tanks, solubility tests have been conducted using nonradioactive, pure metal phases. The metal phases studied included the aluminum phase gibbsite and the iron phases hematite, maghemite, goethite, lepidocrocite, magnetite, and wustite. Many of these mineral phases have been identified in radioactive, High Level Waste sludge at the Savannah River and Hanford Sites. Acids evaluated for dissolution included oxalic, nitric, and sulfuric acids and a variety of other complexing organic acids. The results of the solubility tests indicate that mixtures of oxalic acid with either nitric or sulfuric acid are the most effective cleaning solutions for the dissolution of the primary metal phases in sludge waste. Based on the results, optimized conditions for hematite dissolution in oxalic acid were selected using nitric or sulfuric acid as a supplemental proton source. Electrochemical corrosion studies were also conducted (reported separately; Wiersma, 2010) with oxalic/mineral acid mixtures to evaluate the effects of these solutions on waste tank integrity. The following specific conclusions can be drawn from the test results: (1) Oxalic acid was shown to be superior to all of the other organic acids evaluated in promoting the dissolution of the primary sludge phases. (2) All iron phases showed similar solubility trends in oxalic acid versus pH, with hematite exhibiting the lowest solubility and the slowest dissolution. (3) Greater than 90% hematite dissolution occurred in oxalic/nitric acid mixtures within one week for two hematite sources and within three weeks for a third hematite sample with a larger average particle size. This dissolution rate appears acceptable for waste tank cleaning applications. (4) Stoichiometric dissolution of iron phases in oxalic acid (based on the oxalate concentration) and the formation of the preferred 1:1 Fe to oxalate complex

  3. ALTERNATIVE AND ENHANCED CHEMICAL CLEANING: BASIC STUDIES RESULTS FY2010

    Energy Technology Data Exchange (ETDEWEB)

    King, W.; Hay, M.

    2011-01-24

    In an effort to develop and optimize chemical cleaning methods for the removal of sludge heels from High Level Waste tanks, solubility tests have been conducted using nonradioactive, pure metal phases. The metal phases studied included the aluminum phase gibbsite and the iron phases hematite, maghemite, goethite, lepidocrocite, magnetite, and wustite. Many of these mineral phases have been identified in radioactive, High Level Waste sludge at the Savannah River and Hanford Sites. Acids evaluated for dissolution included oxalic, nitric, and sulfuric acids and a variety of other complexing organic acids. The results of the solubility tests indicate that mixtures of oxalic acid with either nitric or sulfuric acid are the most effective cleaning solutions for the dissolution of the primary metal phases in sludge waste. Based on the results, optimized conditions for hematite dissolution in oxalic acid were selected using nitric or sulfuric acid as a supplemental proton source. Electrochemical corrosion studies were also conducted (reported separately; Wiersma, 2010) with oxalic/mineral acid mixtures to evaluate the effects of these solutions on waste tank integrity. The following specific conclusions can be drawn from the test results: (1) Oxalic acid was shown to be superior to all of the other organic acids evaluated in promoting the dissolution of the primary sludge phases. (2) All iron phases showed similar solubility trends in oxalic acid versus pH, with hematite exhibiting the lowest solubility and the slowest dissolution. (3) Greater than 90% hematite dissolution occurred in oxalic/nitric acid mixtures within one week for two hematite sources and within three weeks for a third hematite sample with a larger average particle size. This dissolution rate appears acceptable for waste tank cleaning applications. (4) Stoichiometric dissolution of iron phases in oxalic acid (based on the oxalate concentration) and the formation of the preferred 1:1 Fe to oxalate complex

  4. Alternative Enhanced Chemical Cleaning Basic Studies Results FY09

    Energy Technology Data Exchange (ETDEWEB)

    Hay, M.; King, W.

    2010-05-05

    Due to the need to close waste storage tanks, chemical cleaning methods are needed for the effective removal of the heels. Oxalic acid is the preferred cleaning reagent for sludge heel dissolution, particularly for iron-based sludge, due to the strong complexing strength of the oxalate. However, the large quantity of oxalate added to the tank farm from oxalic acid based chemical cleaning has significant downstream impacts. Optimization of the oxalic acid cleaning process can potentially reduce the downstream impacts from chemical cleaning. To optimize oxalic acid usage, a detailed understanding of the chemistry of oxalic acid based sludge dissolution is required. Additionally, other acid systems may be required for specific waste components with low solubility in oxalic acid and as a means to reduce oxalic acid usage in general. Solubility tests were conducted using non-radioactive, pure metal phases known to be the primary phases present in High Level Waste sludge. The metal phases studied included the aluminum phases gibbsite and boehmite and the iron phases magnetite and hematite. Hematite and boehmite are expected to be the most difficult iron and aluminum phases to dissolve. These mineral phases have been identified in both SRS and Hanford High Level Waste sludge. Acids evaluated for dissolution included oxalic, nitric, and sulfuric acids. The results of the solubility tests indicate that oxalic and sulfuric acids are more effective for the dissolution of the primary sludge phases. For boehmite, elevated temperature will be required to promote effective phase dissolution in the acids studied. Literature reviews, thermodynamic modeling, and experimental results have all confirmed that pH control using a supplemental proton source (additional acid) is critical for minimization of oxalic acid usage during the dissolution of hematite. These results emphasize the importance of pH control in optimizing hematite dissolution in oxalic acid and may explain the somewhat

  5. Alternative medicine in Paris and Rio de Janeiro: a study on transformative health experiences

    Directory of Open Access Journals (Sweden)

    Elisabeth Eglem

    2014-06-01

    Full Text Available The purpose of this paper is to explore the practice of alternative medicine as an experience capable of modifying the very perception of the body and body feeling, based in a two-field research in France (Paris and Brazil (Rio de Janeiro. In this research, the resort to alternative medicines was considered as urban practice and a possible response to emotional needs, beyond the curative specificities of these medicines. The two countries were chosen for their supposed complementarity concerning the perception of spirituality and therefore, the perception of holistic health concepts. The study relies on an inductive approach and a qualitative methodology: introspective interviews with consumers and professionals, as well as participant observations. After a review of the theoretical aspects on the subject — concepts related to health, alternative medicine, transformative experience —, empirical results are presented. They show that the experience of alternative medicine tends to modify body perception, understood as how individuals define their own body. It also tends to modify body internal feeling, literally how people feel their body. The second conclusion that can be drawn from our study is that, beyond cultural specificities, some similarities appear in the way the practice of alternative medicine impacts on body perception and individual values. In that sense, alternative medicine practices in big urban centers appear to be related to a global consumer culture. However, alternative health behaviors rely on a subjective quest of sense which can be expressed through a variety of practices related to better health, not necessarily involving consumption.

  6. Charcoal-Oil Mixture as an Alternative Fuel: A Preliminary Study

    Directory of Open Access Journals (Sweden)

    Roila Awang

    2009-01-01

    Full Text Available The fast depletion of fuel oil and continuous increase in the demand for power is a global issue. The world energy consumption is projected to grow at an average of 2.7-3.7% from 1996 to 2010. Therefore search for alternative fuel is highly prioritized. Thus this study presents the results on the characteristic of charcoal-oil mixture as an alternative fuel. The calorific value, ash content and stability of the mixture are determined.

  7. Mediation and alternative media, or relocating the centre of media and communication studies

    OpenAIRE

    Couldry, Nick

    2002-01-01

    Alternative media should not be marginal, but central, to the developing agenda of media and communication studies, because they challenge the massive concentration of 'symbolic power' (Bourdieu) in mainstream media institutions and the resulting 'exclusion' of most people 'from the power of naming' (Melucci). Precisely because alternative media organisations, in relative terms, lack symbolic resources, their activities tend to be largely invisible, but that is no reason why, as 'weapons of t...

  8. Alternative Policy Study: Environment and energy in Europe and Central Asia 1990-2010. Energy-related environmental impacts of policy scenarios GEO-2000 alternative policy study

    OpenAIRE

    Vuuren DP van; Bakkes JA; United Nations Environment Progamme (UNEP); MNV

    2000-01-01

    The GEO-2000 study into alternative policy options for Europe and Central Asia focuses on energy use as an important driver for environmental problems across the region. The problems analyzed are climate change, acidification, summer smog, urban air pollution and risks of reactor accidents associated with nuclear power generation. The analysis includes the effects on biodiversity and population health. It considers the question of what can be achieved by moderate measures, and wheter this wil...

  9. Project on Alternative Systems Study - PASS. Cost comparison of repository systems

    International Nuclear Information System (INIS)

    The development of alternative repository systems and different canister alternatives is being studied by SKB within the frame of the 'Project on Alternative Systems Study, PASS', with the objective of presenting a ranking of systems being currently studied. The rankings is primarily made for three different headings: technology, long-term performance and safety, and costs. The ranking for each of these headings are eventually to be merged into one ranking. The present report presents the basis for the ranking regarding costs. The following four systems have been studied and are presented in order of cost (the less expensive first): Medium Long Holes (MLH), KBS-3 (Modified Plan 92 system), Very Long Holes (VLH), and Very Deep Holes (VDH). A significant outcome of the study was the clear difference in cost between the very expensive system VDH and the other three

  10. Establishment and application of minigene models for studying pre-mRNA alternative splicing

    Institute of Scientific and Technical Information of China (English)

    LI Jing; CHEN Xianhua; LIN Wanmin; LI Lishu; HAN Yu; XU Ping

    2004-01-01

    The objective of the present study is to establish a minigene model for studying pre-mRNA alternative splicing. To prepare the minigene DNA constructs, with human or mouse genomic DNA as templates, GluR-B , FGF-2R and Zis "minigene" fragments were amplified using PCR and cloned to the eukaryotic expression vectors. The three constructed minigenes and the expression vectors of Tra2?1 and Zis2 were co-transfected in Hela cells. RT-PCR analysis was performed to semi-quantitatively determine the spliced products from the minigenes. The results demonstrated that the constructed minigenes are useful in studying the pre-mRNA alternative splicing in cultured cells. With the established Zis minigene, we for the first time found that Zis2 isoform regulates the alternative splicing of Zis minigene.

  11. An Interpretive Study of Yosemite National Park Visitors' Perspectives Toward Alternative Transportation in Yosemite Valley

    Science.gov (United States)

    White, Dave D.

    2007-01-01

    The National Park Service (NPS) is increasingly focusing on alternative transportation systems in national parks to address environmental and social problems arising from a historical reliance on personal automobiles as the primary means of visitor access. Despite the potential advantages, alternative transportation may require a reorientation in the way that Americans have experienced national parks since the advent of auto-tourism in the early twentieth century. Little research exists, however, on visitor perspectives towards alternative transportation or the rationale underlying their perspectives. It remains unclear how transportation systems affect visitors’ experiences of the park landscape or the factors influencing their travel behavior in the parks. This report presents an interpretive study of visitor perspectives toward transportation management in the Yosemite Valley area of Yosemite National Park, California. Qualitative analysis of 160 semi-structured interviews identified individual psychological factors as well as situational influences that affect visitors’ behavior and perspectives. Individual psychological factors include perceived freedom, environmental values and beliefs, prior experience with Yosemite National Park and other national parks, prior experience with alternative transportation in national parks, and sensitivity to subjective perceptions of crowding. Situational factors included convenience, access, and flexibility of travel modes, as well as type of visit, type of group, and park use level. Interpretive communication designed to encourage voluntary visitor use of alternative transportation should focus on these psychological and situational factors. Although challenges remain, the results of this study suggest approaches for shaping the way Americans visit and experience their national parks to encourage environmental sustainability.

  12. A case study of alternatively trained science teachers: Attainment of pedagogical content knowledge

    Science.gov (United States)

    Duncan, Benjamin R.

    Elements essential to effective teaching are closely aligned with the domains of a teacher's pedagogical content knowledge (PCK) (Park & Oliver, 2008). Often, alternatively trained teachers enter the teaching profession lacking exposure to pedagogical events that allow these educators opportunities to reflect on their practice and construction of their PCK (Friedrichsen et al., 2007); yet little is known about the knowledge of experienced alternatively trained educators and the complexities associated with their PCK development. The purpose of this study was to describe the nature and sources of alternatively trained secondary school science teachers' PCK after gaining classroom experience. The Park and Oliver (2008) hexagon PCK model was used as the theoretical framework. A case study of two experienced secondary science teachers at a school in the southeastern region of the United States was conducted. Data were collected from multiple sources, such as interviews, classroom observations, participant field journals, lesson plans, classroom assignments, classroom assessments, and researcher's field notes. Data analysis was conducted using the constant comparative method, qualitative deductive analysis, and a content representation. The results showed that experienced alternatively trained science teachers' PCK development was heavily influenced by each teacher's orientation to science teaching. Alternatively trained science teachers compensated for their lack of pedagogical training by relying heavily upon their content knowledge, their knowledge of students, and past experiences. Even after gaining years of experience in a school setting, alternatively trained teachers still lacked familiarity with traditional educational terminology and practices, rather relying upon instructional approaches and techniques independently acquired while each teacher was in "survival" mode. This study provides several implications for teacher preparation, research, and policy.

  13. Spontaneously Fluctuating Motor Cortex Excitability in Alternating Hemiplegia of Childhood: A Transcranial Magnetic Stimulation Study

    Science.gov (United States)

    Stern, William M.; Desikan, Mahalekshmi; Hoad, Damon; Jaffer, Fatima; Strigaro, Gionata; Sander, Josemir W.; Rothwell, John C.; Sisodiya, Sanjay M.

    2016-01-01

    Background Alternating hemiplegia of childhood is a very rare and serious neurodevelopmental syndrome; its genetic basis has recently been established. Its characteristic features include typically-unprovoked episodes of hemiplegia and other transient or more persistent neurological abnormalities. Methods We used transcranial magnetic stimulation to assess the effect of the condition on motor cortex neurophysiology both during and between attacks of hemiplegia. Nine people with alternating hemiplegia of childhood were recruited; eight were successfully tested using transcranial magnetic stimulation to study motor cortex excitability, using single and paired pulse paradigms. For comparison, data from ten people with epilepsy but not alternating hemiplegia, and ten healthy controls, were used. Results One person with alternating hemiplegia tested during the onset of a hemiplegic attack showed progressively diminishing motor cortex excitability until no response could be evoked; a second person tested during a prolonged bilateral hemiplegic attack showed unusually low excitability. Three people tested between attacks showed asymptomatic variation in cortical excitability, not seen in controls. Paired pulse paradigms, which probe intracortical inhibitory and excitatory circuits, gave results similar to controls. Conclusions We report symptomatic and asymptomatic fluctuations in motor cortex excitability in people with alternating hemiplegia of childhood, not seen in controls. We propose that such fluctuations underlie hemiplegic attacks, and speculate that the asymptomatic fluctuation we detected may be useful as a biomarker for disease activity. PMID:26999520

  14. A case study of a novice college student's alternative framework and learning of force and motion

    Science.gov (United States)

    Tasar, Mehmet Fatih

    A case study design was used to investigate in detail one female freshman college student's alternative conceptions, alternative framework and learning of force and motion during a short small group instruction and subsequent tutoring interviews. The researcher in this study acted as the teacher of the small group and the tutor for the interviews. The student who participated in this study had a very limited physics learning experience: during her prior schooling she had taken only a seventh grade physical science course. Although she could remember some information, her conceptions were mostly based on her daily experiences and expectations. Analysis of data showed that during interaction with the teacher-researcher the student seemed to be undergoing conceptual development. However, repeated interviews after the short small group instruction provided evidence that after each session she reverted back to her prior conceptions. An analysis of her alternative conceptions revealed that her alternative framework was significantly different from the Newtonian framework and did not include acceleration for explaining force and motion. It was also revealed that her knowledge base was primarily a collection of expectations for each possible situation. Thus, her learning was characterized as adding or changing factual knowledge to her existing structure. This study suggests that the concept of acceleration plays a central role in learning force and motion in congruence with Newton's laws. Otherwise, a conceptual integration of the concepts of force, motion, and acceleration cannot be achieved and the knowledge base remains fragmented. Implications for further research are also included.

  15. Reflexive Photography as an Alternative Method for the Study of the Freshman Year Experience.

    Science.gov (United States)

    Harrington, Charles E.; Schibik, Timothy J.

    2003-01-01

    Describes alternative method for studying first-year students' impressions of first-semester experiences. Undergraduates were asked to take a series of reflexive photographs, then, in writing describe the reasons why they illustrate their experiences. Research revealed a number of primary themes, including perceptions about the university's…

  16. Studying Effects of Transcranial Alternating Current Stimulation on Hearing and Auditory Scene Analysis

    NARCIS (Netherlands)

    Riecke, Lars

    2016-01-01

    Recent studies have shown that perceptual detection of near-threshold auditory events may depend on the relative timing of the event and ongoing brain oscillations. Furthermore, transcranial alternating current stimulation (tACS), a non-invasive and silent brain stimulation technique, can entrain co

  17. Alternative Conceptions in Animal Classification Focusing on Amphibians and Reptiles: A Cross-Age Study

    Science.gov (United States)

    Yen, Chiung-Fen; Yao, Tsung-Wei; Chiu, Yu-Chih

    2004-01-01

    This study examined students' alternative conceptions of reptiles and amphibians and the extent to which these conceptions remain intact through the elementary (grades 4 and 6), junior, and senior high school years. We administered multiple-choice and free-response instruments to a total of 513 students and interviewed at least 20 students at each…

  18. An Alternative Counseling Model for Alcohol Abuse in College: A Case Study

    Science.gov (United States)

    Hayes, B. Grant; Curry, Jennifer; Freeman, Mark S.; Kuch, Tyson H.

    2010-01-01

    Abstinence education remains a prevailing approach for addressing college student alcohol abuse. This case study illustrates an alternative method of intervening that combines motivational interviewing, harm reduction, and a brief solution-focused model. The counseling approach illustrated emphasizes reduction in, rather than abstinence from,…

  19. Korean Word Frequency and Commonality Study for Augmentative and Alternative Communication

    Science.gov (United States)

    Shin, Sangeun; Hill, Katya

    2016-01-01

    Background: Vocabulary frequency results have been reported to design and support augmentative and alternative communication (AAC) interventions. A few studies exist for adult speakers and for other natural languages. With the increasing demand on AAC treatment for Korean adults, identification of high-frequency or core vocabulary (CV) becomes…

  20. ECONOMY LITERACY STEP BY STEP: THE ALTERNATIVE WAYS FOR THE SOCIAL STUDIES LESSONS

    OpenAIRE

    Akhan, Nadire Emel

    2013-01-01

    The aim of this study is to give suggestions increasing the economy literacy levels of the students at the primary school level. The alternative ways were presented to the teachers for the Social Studies lessons by examining the samples in the literature in this direction. This study is in the literature scanning model. Today’s students shall face with more complicated economy subjects while making the decisions that will affect their lives when they became adults. The individuals not literat...

  1. Web Service Clients on Mobile Android Devices: A Study on Architectural Alternatives and Client Performance

    OpenAIRE

    Knutsen, Johannes

    2009-01-01

    This paper studies Android, a new open source software stack initiated by Google, and the possibilities of developing a mobile client for MPower, a service oriented architecture platform based upon SOAP messaging. The study focuses on the architectural alternatives, their impacts on the mobile client application, Android’s performance on SOAP messaging, and how Web services’ design can be optimized to give well performing Android clients. The results from this study shows how different arch...

  2. Final cost reduction study for the Geysers Recharge Alternative. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-01

    The purpose of this study is to determine whether or not cost reduction opportunities exist for the Geysers Recharge Alternative as defined in the Santa Rosa Subregional Long-Term Wastewater Project EIR/EIS. The City of Santa Rosa has been directed to have a plan for reclaimed water disposal in place by 1999 which will meet future capacity needs under all weather conditions. A Draft EIR/EIS released in July 1996 and a Final EIR certified in June 1997 examine four primary alternatives plus the No Action Alternative. Two of the primary alternatives involve agricultural irrigation with reclaimed water, either in western or southern Sonoma County. Another involves increased discharge of reclaimed water into the Russian River. The fourth involves using reclaimed water to replenish the geothermal reservoir at the Geysers. The addition of this water source would enable the Geysers operators to produce more steam from the geothermal area and thereby prolong the life and economic production level of the steamfield and the geothermal power plants supplied by the steamfield. This study provides additional refined cost estimates for new scenarios which utilize an alternative pipeline alignment and a range of reclaimed water flows, which deliver less water to the Geysers than proposed in the EIR/EIS (by distributing flow to other project components). Also, electrical power rates were revised to reflect the recent changes in costs associated with deregulation of the power industry. In addition, this report provides information on sources of potential public and private funding available and future environmental documentation required if the cost reduction scenarios were to be selected by the City as part of their preferred alternative.

  3. Alternative Education: A Comparative Case Study of the Behavior Modification Programs of Two Upstate South Carolina Alternative Schools for Youth Who Exhibit Behavior That Is Disruptive

    Science.gov (United States)

    Scipio, Timothy Lamont

    2013-01-01

    This study examined behavior modification programs in schools designed to focus on discipline and that aim to reform disruptive behavior in students, usually over a limited period of time. This was a comparative case study of two type II alternative schools in the Upstate of South Carolina. The findings contributed to the research base regarding…

  4. Report on the Savannah River Site aluminum-based spent nuclear fuel alternatives cost study

    International Nuclear Information System (INIS)

    Initial estimates of costs for the interim management and disposal of aluminum-based spent nuclear fuel (SNF) were developed during preparation of the Environmental Impact Statement (EIS) on the Nuclear Weapons Nonproliferation Policy Concerning Foreign Research Reactor Spent Nuclear Fuel. The Task Team evaluated multiple alternatives, assessing programmatic, technical, and schedule risks, and generated life-cycle cost projections for each alternative. The eight technology alternatives evaluated were: direct co-disposal; melt and dilute; reprocessing; press and dilute; glass material oxidation dissolution system (GMODS); electrometallurgical treatment; dissolve and vitrify; and plasma arc. In followup to the Business Plan that was developed to look at SNF dry storage, WSRC prepared an addendum to the cost study. This addendum estimated the costs for the modification and use of an existing (105L) reactor facility versus a greenfield approach for new facilities (for the Direct Co-Disposal and Melt and Dilute alternatives). WSRC assessed the impacts of a delay in reprocessing due to the potential reservation of H-Canyon for other missions (i.e., down blending HEU for commercial use or the conversion of plutonium to either MOX fuel or an immobilized repository disposal form). This report presents the relevant results from these WSRC cost studies, consistent with the most recent project policy, technology implementation, canyon utilization, and inventory assumptions. As this is a summary report, detailed information on the technical alternatives or the cost assumptions raised in each of the above-mentioned cost studies is not provided. A comparison table that briefly describes the bases used for the WSRC analyses is included as Appendix A

  5. Magnetic Force Microscopy Study of Alternate Sputtered (001) Oriented L10 Phase FePt Films

    Institute of Scientific and Technical Information of China (English)

    XIA Ai-Lin; CAO Jiang-Wei; TONG Liu-Niu; WEI Fu-Lin; YANG Zheng; HAN Bao-Shan

    2007-01-01

    @@ We present a magnetic force microscopy study of alternate sputtered (001) oriented L10 phase FePt films. It is found that the root-mean-square value of phase shift of magnetic force images, (△φ) can be used to char acterize the perpendicular anisotropy for a series of specimens. Therefore, the considerable improvement of the perpendicular anisotropy after post-annealing can be characterized.

  6. Designing medical and educational intervention studies. A review of some alternatives to conventional randomized controlled trials

    OpenAIRE

    Bradley, Clare

    1993-01-01

    The advantages and limitations of RCT designs are discussed, and a range of alternative designs for medical and educational intervention studies considered. Designs selected are those that address the much neglected psychological issues involved in the recruitment of patients and allocation of patients to treatments within trials. Designs include Zelen's (18) randomized consent design, Brewin and Bradley's (20) partially randomized patient-centered design, and Korn and Baumrind's (21) partial...

  7. Substance use and dietary practices among students attending alternative high schools: results from a pilot study

    Directory of Open Access Journals (Sweden)

    Hannan Peter J

    2011-04-01

    Full Text Available Abstract Background Substance use and poor dietary practices are prevalent among adolescents. The purpose of this study was to examine frequency of substance use and associations between cigarette, alcohol and marijuana use and selected dietary practices, such as sugar-sweetened beverages, high-fat foods, fruits and vegetables, and frequency of fast food restaurant use among alternative high school students. Associations between multi-substance use and the same dietary practices were also examined. Methods A convenience sample of adolescents (n = 145; 61% minority, 52% male attending six alternative high schools in the St Paul/Minneapolis metropolitan area completed baseline surveys. Students were participants in the Team COOL (Controlling Overweight and Obesity for Life pilot study, a group randomized obesity prevention pilot trial. Mixed model multivariate analyses procedures were used to assess associations of interest. Results Daily cigarette smoking was reported by 36% of students. Cigarette smoking was positively associated with consumption of regular soda (p = 0.019, high-fat foods (p = 0.037, and fast food restaurant use (p = 0.002. Alcohol (p = 0.005 and marijuana use (p = 0.035 were positively associated with high-fat food intake. With increasing numbers of substances, a positive trend was observed in high-fat food intake (p = 0.0003. There were no significant associations between substance use and fruit and vegetable intake. Conclusions Alternative high school students who use individual substances as well as multiple substances may be at high risk of unhealthful dietary practices. Comprehensive health interventions in alternative high schools have the potential of reducing health-compromising behaviors that are prevalent among this group of students. This study adds to the limited research examining substance use and diet among at-risk youth. Trial registration number ClinicalTrials.gov: NCT01315743

  8. Enhancing Fluoride: Clinical Human Studies of Alternatives or Boosters for Caries Management.

    Science.gov (United States)

    Fontana, Margherita

    2016-01-01

    Dental caries remains a major public health problem, especially for certain high-risk population groups. The goal of this study was to assess the evidence regarding strategies meant to be used as alternatives or booster/supplements to fluoride for caries prevention and management. Articles were selected for inclusion if they had a prospective longitudinal design, with a fluoride control arm, and were conducted in human subjects. Of the included studies, 7/18 studies on calcium-based strategies favored the test product (the majority of studies included exposure of fluoride in all groups). All the arginine studies (8/8) included a combination of arginine and a calcium base, and concluded that this has the potential to significantly boost the performance of fluoride. The remaining included studies focused on the addition of microbial-related strategies to a fluoride-containing vehicle (2 xylitol studies and 1 study using a probiotic milk), and all favored the combination as a booster to fluoride. Thus, the current study did not identify evidence for any strategy to effectively be used as a substitute or alternative to fluoride, but identified some consistent evidence derived from the use of prebiotic strategies (primarily from use of arginine combined with calcium) to support their potential use to boost the mechanism of action of fluoride. Thus, fluoride-based strategies remain the standard for caries prevention and management, with some evidence that boosting the effects of fluoride by the use of prebiotic strategies is a promising possibility. PMID:27100833

  9. Endocrine mediation of vertebrate male alternative reproductive tactics: the next generation of studies.

    Science.gov (United States)

    Knapp, Rosemary

    2003-11-01

    In many species of animals, males may achieve reproductive success via one of several alternative reproductive tactics. Over the past decade or so, there has been a concerted effort to investigate endocrine mechanisms that underlie such discrete behavioral (and often morphological) variation. In vertebrates, the first generation of studies focused on potential organizational or activational effects of steroid hormones (Moore, 1991; Moore et al., 1998). Some of these studies have made it clear that, in addition to circulating hormone levels, one must also consider other aspects of the endocrine system, including hormone receptors, binding globulins and potential interactions among endocrine axes. In this paper, I review recent work on endocrine mechanisms and suggest possibilities for future investigation. I highlight how individual variation in sensitivity to environmental conditions, particularly with respect to various stressors, may account for the existence of alternative male reproductive phenotypes. Along these lines, I briefly explain the logic behind our work with male phenotypes of longear sunfish (Lepomis megalotis) that is aimed at determining the tissue-specific distribution and activity of two enzymes that are common to androgen and glucocorticoid metabolism. A major goal of our work is to examine the potential role of steroidogenic enzymes in the transduction of environmental information to influence the expression of alternative male reproductive phenotypes. PMID:21680474

  10. Study on ultra-precision magnetic abrasive finishing process using low frequency alternating magnetic field

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Jinzhong, E-mail: wjz.0926@163.com; Zou, Yanhua, E-mail: yanhua@cc.utsunomiya-u.ac.jp; Sugiyama, Hitoshi, E-mail: sugiyama@cc.utsunomiya-u.ac.jp

    2015-07-15

    We proposed a new ultra-precision magnetic abrasive finishing (MAF) process using low frequency alternating magnetic field in this paper. Magnetic cluster themselves may produce the up and down movement change under alternating magnetic force. The movement may not only promote the dispersion of micro-magnetic particles, but also improve stirring effect and cross-cutting effects of the abrasives, achieving circulation and update to ensure the stability of grinding tools. This process is considered to be able to efficiently apply in ultra-precision finishing of plane and complicated micro-surfaces. In this study, we investigated the effects of alternating magnetic field on magnetic field distribution, finishing force and abrasive behavior. Furthermore, a set of experimental devices have been designed for finishing SUS304 stainless steel plate. The present work is aimed at understanding finishing particularity of this process and studying impacts of important process parameters namely grinding fluid, rotational speed of magnetic pole, current frequency on change in finish surface and material removal. Experimental results indicate that the process can realize ultra-precision finishing of plane by using oily grinding fluid. In the present research, the surface roughness of SUS304 stainless steel plate was improved from 240.24 nm to 4.38 nm by this process. - Highlights: • We investigated magnetic field distribution in processing region. • Magnetic cluster can produce a fluctuating finishing force in alternating magnetic field. • Oily grinding fluid is more applicable to this process. • Few nanometer finish surface can be obtained by this process.

  11. Study on ultra-precision magnetic abrasive finishing process using low frequency alternating magnetic field

    International Nuclear Information System (INIS)

    We proposed a new ultra-precision magnetic abrasive finishing (MAF) process using low frequency alternating magnetic field in this paper. Magnetic cluster themselves may produce the up and down movement change under alternating magnetic force. The movement may not only promote the dispersion of micro-magnetic particles, but also improve stirring effect and cross-cutting effects of the abrasives, achieving circulation and update to ensure the stability of grinding tools. This process is considered to be able to efficiently apply in ultra-precision finishing of plane and complicated micro-surfaces. In this study, we investigated the effects of alternating magnetic field on magnetic field distribution, finishing force and abrasive behavior. Furthermore, a set of experimental devices have been designed for finishing SUS304 stainless steel plate. The present work is aimed at understanding finishing particularity of this process and studying impacts of important process parameters namely grinding fluid, rotational speed of magnetic pole, current frequency on change in finish surface and material removal. Experimental results indicate that the process can realize ultra-precision finishing of plane by using oily grinding fluid. In the present research, the surface roughness of SUS304 stainless steel plate was improved from 240.24 nm to 4.38 nm by this process. - Highlights: • We investigated magnetic field distribution in processing region. • Magnetic cluster can produce a fluctuating finishing force in alternating magnetic field. • Oily grinding fluid is more applicable to this process. • Few nanometer finish surface can be obtained by this process

  12. Alternative sieving method for extraction of light filth from cheeses: collaborative study.

    Science.gov (United States)

    Nakashima, M J

    1994-01-01

    A collaborative study was conducted on an alternative sieving method for the extraction of light filth from cheeses. The alternative method was developed that is applicable to broad variety of cheeses. A 225 g test portion is dispersed in a solution of 5.7% HCl, Igepal CO-730, and Igepal DM-710. Digested cheese is wet-sieved on a No. 230 sieve. The residue is treated with Tergitol Anionic 4, transferred to 1% sodium lauryl sulfate solution, heated, and maintained at 65 degrees-75 degrees C for 10 min. The residue is washed with these 2 surfactants a maximum of 4 times until it is reduced to an amount that is filterable. The residue is filtered and the filter papers are examined microscopically at a magnification of ca 30x. Average recoveries by 9 collaborators for 3 spike levels of rat hairs (5, 10, and 15) were 80, 68, and 81%, respectively; for insect fragments (5, 15, and 30) recoveries were 97, 90, and 92%, respectively. The alternative sieving method for extraction of light filth from cheeses has been adopted first action by AOAC INTERNATIONAL. PMID:7950417

  13. Study of Volumetric Efficiency for Spark Ignition Engines Using Alternative Fuels

    Directory of Open Access Journals (Sweden)

    Adrian Irimescu

    2010-10-01

    Full Text Available One of the most important parameter for spark ignition engines is volumetric efficiency, as it directly influences specific power output. Several definitions of this parameter are studied from a theoretical point of view, taking into consideration the use of alternative fuels. The influence of using gasoline-bioethanol blends is investigated, as well as the effect of fuelling spark ignition engines with methane, liquefied petroleum gas and hydrogen. Bioethanol features the highest volumetric efficiency, while gaseous fuels cause a drop in specific power output compared to gasoline operation.

  14. Optimization studies for the prism alternative oxide core, and its response to the actinide burning strategy

    International Nuclear Information System (INIS)

    The PRISM advanced liquid metal reactor is designed by General Electric in a reference solution equipped by a metal fuelled core. An alternative oxide core is studied by General Electric and ENEA in the frame of a collaboration existing since 1989. This paper deals with the ENEA contribution on the oxide solution, aimed at the core optimization both from safety parameters and fuel cycle economy points of view. Moreover, synthetic information about ENEA evaluations about the minor actinide burning capability of the PRISM oxide core are given. (author)

  15. School Process and Teacher Job Satisfaction at Alternative Schools: A Multilevel Study Using SASS 2007-08 Data

    Science.gov (United States)

    Xia, Jiangang; Izumi, Masashi; Gao, Xingyuan

    2015-01-01

    This study examined the associations between public alternative schools' teacher job satisfaction and school processes. Based on a multilevel analysis of the national School and Staffing Survey 2007-08 data, we found that among the seven school processes, public alternative schools' administrative support, staff collegiality, career and working…

  16. Preliminary studies of alternative feed additives for broilers: Alternanthera brasiliana extract, propolis extract and linseed oil

    Directory of Open Access Journals (Sweden)

    MW Biavatti

    2003-05-01

    Full Text Available The influence of alternative treatments using fluidextracts of Alternanthera brasiliana, propolis resin and linseed oil on the performance and blood biochemistry of broilers was evaluated. The study was done with five treatments: basal diet (negative control; basal diet + 40 ppm avylamicin and 120 ppm monensin (positive control; basal diet + A. brasiliana extract (180 mL/200 kg of feed; basal diet + propolis extract (200 mL/200 kg of feed and basal diet + linseed oil (2.5% replacing soybean oil. Propolis and A. brasiliana extracts improved broiler performance from 14 to 21 days, whereas linseed oil had no effect. The findings of this experiment revealed that A. brasiliana and propolis extracts can be used as antimicrobials, but further studies are necessary to find the best concentration in broiler diets.

  17. Numerical Study on Plume Interaction Above An Alternating Diffuser in Stagnant Water

    Institute of Scientific and Technical Information of China (English)

    KUANG Cui-ping; LEE Joseph H.W.; LIU Shu-guang; GU Jie

    2006-01-01

    The plume interaction above an alternating diffuser in stagnant water is studied with 3D Reynolds-averaged Navier-Stokes equations (RANS) combined with a buoyancy-extended k-ε model. The steady three-dimensional turbulent flow and temperature fields are computed by use of the finite volume method on a non-uniform high resolution orthogonal grid. The numerical predictions demonstrate a generic flow pattern for different turbulent heated jet discharges: the buoyant jets on each side of the diffuser first merge to form an essentially two-dimensional plume which bends back toward the diffuser centerline due to a low pressure cavity. In general, an under-pressure exists in the cavity until the plumes merge; the pressure increases to slightly positive afterwards. Two-dimensionality of the scalar and flow field is attained much later than the point of zero pressure. The position of merging point is governed by mainly four parameters - the discharge densimetric Froude number, the port diameter and space, and the horizontal distance between alternating jet nozzles. A formula from numerical simulations is obtained through regression analysis and it is used to predict the position of plume merging point. The predicted temperature fields are comparable to previous experiments.

  18. Biodiversity loss and turnover in alternative states in the Mediterranean Sea: a case study on meiofauna

    Science.gov (United States)

    Bianchelli, Silvia; Buschi, Emanuela; Danovaro, Roberto; Pusceddu, Antonio

    2016-10-01

    In the Mediterranean Sea hard-bottom macroalgal meadows may switch to alternative and less-productive barrens grounds, as a result of sea urchins overgrazing. Meiofauna (and especially nematodes) represent key components of benthic ecosystems, are highly-diversified, sensitive to environmental change and anthropogenic impacts, but, so-far, have been neglected in studies on regime shifts. We report here that sedimentary organic matter contents, meiofaunal taxa richness and community composition, nematode α- and β-biodiversity vary significantly between alternative macroalgal and barren states. The observed differences are consistent in six areas spread across the Mediterranean Sea, irrespective of barren extent. Our results suggest also that the low biodiversity levels in barren states are the result of habitat loss/fragmentation, which is associated also with a lower availability of trophic resources. Furthermore, differences in meiofaunal and nematode abundance, biomass and diversity between macroalgal meadow and barren states persist when the latter is not fully formed, or consists of patches interspersed in macroalgal meadows. Since barren grounds are expanding rapidly along the Mediterranean Sea and meiofauna are a key trophic component in marine ecosystems, we suggest that the extension and persistence of barrens at the expenses of macroalgal meadows could also affect resilience of higher trophic level.

  19. Pulse Intravenous Clomipramine as an alternative antidepressant treatment to ECT: A pilot study

    Directory of Open Access Journals (Sweden)

    Maj-Liz Persson

    2007-12-01

    Full Text Available Background and Objectives: The aim of the study was to examine the antidepressant effect of a single pulse dose of intravenous clomipramine (200 mg i.v. followed by oral administration as an alternative method to electroconvulsive therapy. Methods: Twenty-one inpatients (8 male, 13 female with major depression were included. Depression severity was measured by Montgomery Asberg Rating Scale (MADRS and Clinical Global Impression severity scale (CGI-S before the pulse dose and 1 week after. The day after the pulse dose, the patient was medicated with 75 mg of oral clomipramine and from day two with 150 mg clomipramine daily. Results: The MADRS score dropped with 39% ± 22% and the CGI score with 28% ± 19% in one week. The improvement of the MADRS score after one week was 13.1 (C.I.9.5-17.0. CGI-ratings dropped from a mean of 5.5 (SD 1.2 to 3.9 (SD 1.1, an improvement of 28% ± 19%.(C.I. 1.0-2.1. Both improvements were significant (p<000.1. Conclusions: Single pulse dose clomipramine administration ameliorates depressive symptoms, and may be an alternative to ECT.

  20. Biodiversity loss and turnover in alternative states in the Mediterranean Sea: a case study on meiofauna

    Science.gov (United States)

    Bianchelli, Silvia; Buschi, Emanuela; Danovaro, Roberto; Pusceddu, Antonio

    2016-01-01

    In the Mediterranean Sea hard-bottom macroalgal meadows may switch to alternative and less-productive barrens grounds, as a result of sea urchins overgrazing. Meiofauna (and especially nematodes) represent key components of benthic ecosystems, are highly-diversified, sensitive to environmental change and anthropogenic impacts, but, so-far, have been neglected in studies on regime shifts. We report here that sedimentary organic matter contents, meiofaunal taxa richness and community composition, nematode α- and β-biodiversity vary significantly between alternative macroalgal and barren states. The observed differences are consistent in six areas spread across the Mediterranean Sea, irrespective of barren extent. Our results suggest also that the low biodiversity levels in barren states are the result of habitat loss/fragmentation, which is associated also with a lower availability of trophic resources. Furthermore, differences in meiofaunal and nematode abundance, biomass and diversity between macroalgal meadow and barren states persist when the latter is not fully formed, or consists of patches interspersed in macroalgal meadows. Since barren grounds are expanding rapidly along the Mediterranean Sea and meiofauna are a key trophic component in marine ecosystems, we suggest that the extension and persistence of barrens at the expenses of macroalgal meadows could also affect resilience of higher trophic level. PMID:27708343

  1. Alternative and traditional assessments: Their comparative impact on students' attitudes and science learning outcomes. An exploratory study

    Science.gov (United States)

    Century, Daisy Nelson

    This probing study focused on alternative and traditional assessments, their comparative impacts on students' attitudes and science learning outcomes. Four basic questions were asked: What type of science learning stemming from the instruction can best be assessed by the use of traditional paper-and pencil test? What type of science learning stemming from the instruction can best be assessed by the use of alternative assessment? What are the differences in the types of learning outcomes that can be assessed by the use of paper-pencil test and alternative assessment test? Is there a difference in students' attitude towards learning science when assessment of outcomes is by alternative assessment means compared to traditional means compared to traditional means? A mixed methodology involving quantitative and qualitative techniques was utilized. However, the study was essentially a case study. Quantitative data analysis included content achievement and attitude results, to which non-parametric statistics were applied. Analysis of qualitative data was done as a case study utilizing pre-set protocols resulting in a narrative summary style of report. These outcomes were combined in order to produce conclusions. This study revealed that the traditional method yielded more concrete cognitive content learning than did the alternative assessment. The alternative assessment yielded more psychomotor, cooperative learning and critical thinking skills. In both the alternative and the traditional methods the student's attitudes toward science were positive. There was no significant differences favoring either group. The quantitative findings of no statistically significant differences suggest that at a minimum there is no loss in the use of alternative assessment methods, in this instance, performance testing. Adding the results from the qualitative analysis to this suggests (1) that class groups were more satisfied when alternative methods were employed, and (2) that the two

  2. Evaluation of microlithographic performance of `deep UV’ resists: Synthesis, and 2D NMR studies on alternating `high ortho’ novolak resins

    Indian Academy of Sciences (India)

    Maneesh Sharma; Anant A Naik; P Raghunathan; S V Eswaran

    2012-03-01

    Lithographic evaluation of a `deep UV’ negative photoresist is discussed along with the synthesis of an alternating `high-ortho’ novolak resin. 2-D NMR studies (COSY, NOESY, HSQC, HMBC) on this resin are also discussed.

  3. Self-administered acupuncture as an alternative to deliberate self-harm: a feasibility study.

    Science.gov (United States)

    Davies, Susan; Bell, Diana; Irvine, Fiona; Tranter, Richard

    2011-12-01

    The aim of this mixed methods feasibility study was to demonstrate the acceptability, practicality, and safety of training patients who regularly use deliberate self harm (DSH) to self-administer acupuncture as an alternative coping skill for emotional distress. Ten adult patients with a diagnosis of emotionally unstable personality disorder who regularly self-harmed were recruited to the study following baseline assessment by a psychiatrist. An acupuncturist taught participants to self-acupuncture. During the 6-week intervention participants recorded their emotional distress, coping behaviors, thoughts, and feelings in a diary. Face-to-face interviews were used to explore participants' motives for DSH and their experience of acupuncture. Framework analysis was conducted on interview transcripts and diary entries to identify common themes. Mood at baseline and six weeks was measured using the BDI and changes in the use of coping behaviors and acupuncture were measured using diary entries. Subjects used acupuncture regularly through the six-week intervention and over this period there was a reduction in the frequency of DSH. Qualitative analysis identified two broad themes relating to the process and the effects of acupuncture. There was wide variation in the effects experienced by subjects which broadly mapped onto to the wide range of motives behind DSH. BDI scores showed a near significant reduction (p = 0.055) from 44.4. to 34.4 over the 6-week intervention. Patients presenting with deliberate self harm can be safely trained to self-administer acupuncture as an alternative coping skill. Acceptability and effectiveness may vary between patients depending on the complex motives underlying their self-harming behavior. While the pilot study was designed to explore the feasibility of the intervention, results from this limited sample suggest that use of self-administered acupuncture may reduce the frequency of self harming behavior and reduce emotional distress as

  4. Complementary alternative medicine use among patients with dengue fever in the hospital setting: a cross-sectional study in Malaysia

    OpenAIRE

    Ching, SiewMooi; Ramachandran, Vasudevan; Gew, Lai Teck; Lim, Sazlyna Mohd Sazlly; Sulaiman, Wan Aliaa Wan; Foo, Yoke Loong; Zakaria, Zainul Amiruddin; Samsudin, Nurul Huda; Lau, Paul Chih Ming Chih; Veettil, Sajesh K; Hoo, Fankee

    2016-01-01

    Background In Malaysia, the number of reported cases of dengue fever demonstrates an increasing trend. Since dengue fever has no vaccine or antiviral treatment available, it has become a burden. Complementary and alternative medicine (CAM) has become one of the good alternatives to treat the patients with dengue fever. There is limited study on the use of CAM among patients with dengue fever, particularly in hospital settings. This study aims to determine the prevalence, types, reasons, expen...

  5. Closure Alternatives for Municipal Waste Landfills.Study Case: Municipal Waste Landfill Medias,Sibiu County

    Directory of Open Access Journals (Sweden)

    MIHĂIESCU R.

    2010-12-01

    Full Text Available In the recent decades, the environmental impact produced by municipal solid wastes has received specialattention. All new EU countries are involved in the process of implementation of the European Council Directive31/99/EC on the landfill of waste in the European Union. As consequence National legislation, adapted to fit the EUrequirements, focuses on integrated waste management and environmental control of municipal solid waste landfills,from start-up to closure and assimilation into the environment. In Romania, by Government decision, HG 349/2005,was established the obligatoriness of closing unconform waste landfills located in urban areas starting at July 2009. Asconsequence the owner of municipal waste landfill Medias started the proceedings of closure for the landfill. The aim ofthis study is to compare, from an environmental point of view, different alternatives for the closure of the municipalsolid waste landfill Somard-Medias (Romania.

  6. Prevalence of musculoskeletal disorder and alternative medicine therapies among dentists of North India: A descriptive study

    Directory of Open Access Journals (Sweden)

    Devanand Gupta

    2015-01-01

    Full Text Available Aim: Health professionals especially the dental professional are the frequent targets of musculoskeletal disorders (MSD. Complementary and alternative medicine (CAM can be of some help in managing these MSD especially in. The purpose of this study was to determine the prevalence of CAM therapies as a treatment modality for MSD management among dental professionals of north India. Materials and Methods: Registered dentist of North Indian origin, India (n = 3598 were included in the study. The questionnaire was sent to all the dentists which consisted of the demographic profile, MSD in the past year, CAM therapies utilization and opinion about CAM therapies. Data analysis was done using SPSS version 21 and data were presented in tabular and graphic form. Test of significance was done using chi-square statistics with P < 0.05 considered as significant. Results: A response rate of 80% (n = 2879 was obtained, and all complained of MDS in some or the other part of their life. The use of CAM was reported among 70% (n = 2015 of the dentist who suffered from MSD. Other dentists either used conventional treatment or did not use anything. Conclusion: As the name implies, alternative medical systems is a category that extends beyond a single modality and refers to an entire system of theory and practice that developed separately from conventional medicine. CAM should be subject to rigorous scientific inquiry so that interventions that work are systematically distinguished from those that do not. In addition, the use of CAM treatments should be based on evidence of effectiveness and safety as demonstrated in randomized clinical trials.

  7. Environmental assessment of alternative municipal solid waste management strategies. A Spanish case study.

    Science.gov (United States)

    Bovea, M D; Ibáñez-Forés, V; Gallardo, A; Colomer-Mendoza, F J

    2010-11-01

    The aim of this study is to compare, from an environmental point of view, different alternatives for the management of municipal solid waste generated in the town of Castellón de la Plana (Spain). This town currently produces 207 ton of waste per day and the waste management system employed today involves the collection of paper/cardboard, glass and light packaging from materials banks and of rest waste at street-side containers. The proposed alternative scenarios were based on a combination of the following elements: selective collection targets to be accomplished by the year 2015 as specified in the Spanish National Waste Plan (assuming they are reached to an extent of 50% and 100%), different collection models implemented nationally, and diverse treatments of both the separated biodegradable fraction and the rest waste to be disposed of on landfills. This resulted in 24 scenarios, whose environmental behaviour was studied by applying the life cycle assessment methodology. In accordance with the ISO 14040-44 (2006) standard, an inventory model was developed for the following stages of the waste management life cycle: pre-collection (bags and containers), collection, transport, pre-treatment (waste separation) and treatment/disposal (recycling, composting, biogasification+composting, landfill with/without energy recovery). Environmental indicators were obtained for different impact categories, which made it possible to identify the key variables in the waste management system and the scenario that offers the best environmental behaviour. Finally, a sensitivity analysis was used to test some of the assumptions made in the initial life cycle inventory model. PMID:20381331

  8. Cheese is a reliable alternative meal for solid-phase gastric emptying study.

    Science.gov (United States)

    Drubach, Laura A; Kourmouzi, Vasiliki; Fahey, Frederic H

    2010-05-01

    We evaluated the labeling stability of several alternative meals that could be used to perform solid-phase gastric emptying study. Cooked egg whites labeled with technetium-99m sulfur colloid served as a control. Packaged instant oatmeal and instant mashed potatoes were prepared by adding hot water. Cheddar cheese was melted. Peanut butter was added to bread. The different meals were mixed with technetium-99m sulfur colloid (2.2-3.7 MBq), chopped into small pieces and placed in a glass tube containing gastric juice. Four samples of each meal were analyzed after 1 and 4 h of agitation with a 3-D rotator (two samples per time point). The meal samples were washed with 2 ml of saline and filtered using a blood transfusion filter. The activity in each sample before and after filtering was assayed in a dose calibrator. The percentage of initial radioactivity remaining with the meal of admixture with gastric juice was measured and the average of the two samples was taken. The percentage of activity bound to the solid phase was 98.2+/-1.9, 95.6+/-1.1, 62.1+/-1.7, 41.8+/-0.6, and 74.5+/-3.8% at 1 h and 98.5+/-1.0, 95.8+/-2.6, 77.2+/-6.8, 55.5+/-3.4 and 40.2+/-22.1 at 4 h for egg whites, cheese, oatmeal, mashed potatoes and peanut butter respectively. For egg whites and cheese, there was no significant difference between the values at 1 and 4 h (P>0.8). Cheddar cheese provides an alternative meal for assessing solid gastric emptying in children comparable to egg whites. Oatmeal and mashed potatoes had low and variable labeling stability and are not recommended. In view of the significant proportion of pediatric patients who refuse to eat scrambled eggs or have allergy to eggs, the availability of other meal choices is essential. The versatility of cheddar cheese, which can be added to macaroni or as a topping on pizza, makes it a useful alternative to labeled eggs. PMID:20145582

  9. ECONOMY LITERACY STEP BY STEP: THE ALTERNATIVE WAYS FOR THE SOCIAL STUDIES LESSONS

    Directory of Open Access Journals (Sweden)

    Nadire Emel AKHAN

    2013-06-01

    Full Text Available The aim of this study is to give suggestions increasing the economy literacy levels of the students at the primary school level. The alternative ways were presented to the teachers for the Social Studies lessons by examining the samples in the literature in this direction. This study is in the literature scanning model. Today’s students shall face with more complicated economy subjects while making the decisions that will affect their lives when they became adults. The individuals not literate economically and who are void of applying the economic judgment skills, shall consider the economic problems faced by them when both they were young and also they became adults complicated and threatening. The young people can understand the global economy only when learned the economy subjects and thus they have roles much better in their country’s economic system. Therefore it is quite important for today’s young people to understand how the economy affects the humans’ lives in the triangle of the producer, consumer and good citizen. The activities to be applied by the teachers in the Social Studies lessons while they teach the economy subjects, shall help to the teachers to learn the economy subjects seem hard and complicated in both enjoyable and also permanent ways.

  10. 77 FR 14801 - Request for Information (RFI) on Design of a Pilot Operational Study To Assess Alternative Blood...

    Science.gov (United States)

    2012-03-13

    ... HUMAN SERVICES Request for Information (RFI) on Design of a Pilot Operational Study To Assess... obtain information relevant to the design of a pilot operational study (or studies) on alternative donor... recognition of the challenges of designing such studies. This RFI seeks information from interested...

  11. Preventing long-lasting fear recovery using bilateral alternating sensory stimulation: A translational study.

    Science.gov (United States)

    Wurtz, H; El-Khoury-Malhame, M; Wilhelm, F H; Michael, T; Beetz, E M; Roques, J; Reynaud, E; Courtin, J; Khalfa, S; Herry, C

    2016-05-01

    Posttraumatic stress disorder (PTSD) is a highly debilitating and prevalent psychological disorder. It is characterized by highly distressing intrusive trauma memories that are partly explained by fear conditioning. Despite efficient therapeutic approaches, a subset of PTSD patients displays spontaneous recurrence of traumatic memories after successful treatment. The development of animal behavioral models mimicking the individual variability in treatment outcome for PTSD patients represent therefore an important challenge as it allows for the identification of predicting factors of resilience or susceptibility to relapse. However, to date, only few animal behavioral models of long-lasting fear recovery have been developed and their predictive validity has not been tested directly. The objectives of this study were twofold. First we aimed to develop a simple animal behavioral model of long-lasting fear recovery based on auditory cued fear conditioning and extinction learning, which recapitulates the heterogeneity of fear responses observed in PTSD patients after successful treatment. Second we aimed at testing the predictive validity of our behavioral model and used to this purpose a translational approach based (i) on the demonstration of the efficiency of Eye Movement Desensitization and Reprocessing (EMDR) therapy to reduce conditioned fear responses in PTSD patients and (ii) on the implementation in our behavioral model of an electrical bilateral alternating stimulation of the eyelid which mimics the core feature of EMDR. Our data indicate that electrical bilateral alternating stimulation of the eyelid during extinction learning alleviates long-lasting fear recovery of conditioned fear responses and dramatically reduces inter-individual variability. These results demonstrate the face and predictive validity of our animal behavioral model and provide an interesting tool to understand the neurobiological underpinnings of long-lasting fear recovery. PMID:26091614

  12. Alternative security

    International Nuclear Information System (INIS)

    This book contains the following chapters: The Military and Alternative Security: New Missions for Stable Conventional Security; Technology and Alternative Security: A Cherished Myth Expires; Law and Alternative Security: Toward a Just World Peace; Politics and Alternative Security: Toward a More Democratic, Therefore More Peaceful, World; Economics and Alternative Security: Toward a Peacekeeping International Economy; Psychology and Alternative Security: Needs, Perceptions, and Misperceptions; Religion and Alternative Security: A Prophetic Vision; and Toward Post-Nuclear Global Security: An Overview

  13. Evaluation of Colocasia esculenta Starch as an Alternative Tablet Excipient to Maize Starch: Assessment by Preformulation and Formulation Studies

    OpenAIRE

    Kusuma. R; Venkat Reddy. P; Samba Shiva Rao. A

    2015-01-01

    Starch isolated from Colocasia esculenta plant was studied as an alternative pharmaceutical excipient to maize and potato starch. The Colocasia esculenta starch has been evaluated by series of tests as mentioned in Indian Pharmacopoeia before being used for evaluation. It was tested along with maize and potato starch as an alternative excipient by performing battery of preformulation and formulation tests. The results obtained for Colocasia esculenta starch was comparable with maize starch an...

  14. Theoretical and experimental studies on combustion of alternative fuels in cement kilns

    International Nuclear Information System (INIS)

    In this thesis, the utilization of alternative fuels for NOx reduction by means of reburning and advanced reburning is considered. Laboratory experiments, full-scale experiments and computational fluid dynamic (CFD) simulations are the basis of the thesis. The goal of the work was to characterize alternative fuels used in cement kilns, with focus on the processes taking place in the precalciner of the cement kiln. To facilitate testing under controlled process conditions, a lab-scale circulating fluidized bed combustion (CFBC) reactor was designed and constructed. A co prehensive study on the fluidization regime in CFBC reactors and precalciners was required to ensure and verify that the operational regime in the CFBC reactor was similar to the regime in a precalciner. Different alternative fuels, such as refuse derived fuel, animal meal and solid hazardous waste, were tested in the CFBC reactor, which proved well suited for characterization of alternative fuels and investigations of NOx reduction, even though the operation of a CFBC reactor is quite complex and gives a certain variation in stability. Experiments with and without circulating mass in the CFBC reactor demonstrated the importance of executing the laboratory combustion experiments in an environment similar to that in the full-scale process, i.e. in the precalciner. Animal meal is believed to follow the reduction route of selective non-catalytic r duction or advanced reburning and to have a special capability of reducing NOx during increased NOx concentrations at the reactor inlet. The increased CO emissions during advanced reburning and reburning with animal meal are most likely to be due to the competition for the OH radical during oxidation of CO and of NH3. Furthermore, it was shown, for all fuels, that an increased concentration of NOx at the reactor inlet increases the ratio of NOx at the exit and NOx supplied. Full-scale experiments were executed at Norcem's kiln 6 in Brevik, using solid

  15. Theoretical and experimental studies on combustion of alternative fuels in cement kilns

    Energy Technology Data Exchange (ETDEWEB)

    Axelsen, Ernst Petter

    2002-07-01

    In this thesis, the utilization of alternative fuels for NOx reduction by means of reburning and advanced reburning is considered. Laboratory experiments, full-scale experiments and computational fluid dynamic (CFD) simulations are the basis of the thesis. The goal of the work was to characterize alternative fuels used in cement kilns, with focus on the processes taking place in the precalciner of the cement kiln. To facilitate testing under controlled process conditions, a lab-scale circulating fluidized bed combustion (CFBC) reactor was designed and constructed. A co prehensive study on the fluidization regime in CFBC reactors and precalciners was required to ensure and verify that the operational regime in the CFBC reactor was similar to the regime in a precalciner. Different alternative fuels, such as refuse derived fuel, animal meal and solid hazardous waste, were tested in the CFBC reactor, which proved well suited for characterization of alternative fuels and investigations of NOx reduction, even though the operation of a CFBC reactor is quite complex and gives a certain variation in stability. Experiments with and without circulating mass in the CFBC reactor demonstrated the importance of executing the laboratory combustion experiments in an environment similar to that in the full-scale process, i.e. in the precalciner. Animal meal is believed to follow the reduction route of selective non-catalytic r duction or advanced reburning and to have a special capability of reducing NOx during increased NOx concentrations at the reactor inlet. The increased CO emissions during advanced reburning and reburning with animal meal are most likely to be due to the competition for the OH radical during oxidation of CO and of NH{sub 3}. Furthermore, it was shown, for all fuels, that an increased concentration of NOx at the reactor inlet increases the ratio of NOx at the exit and NOx supplied. Full-scale experiments were executed at Norcem's kiln 6 in Brevik, using

  16. A STUDY ON LIMITATION OF GOVERNMENT INITIATIVE MODEL FOR ALTERNATIVE FUEL VEHICLE (AFV PROMOTION IN CHINA

    Directory of Open Access Journals (Sweden)

    Byunghun Choi

    2016-04-01

    Full Text Available Chinese responsibility for reducing Greenhouse Gas or carbon dioxide emission increases continuously. Chinese government suggested two targets; Alternative Fuel Vehicle output volume 500 thousand and AFV market share 5% by the end of 2011. However any of two targets did not come true. Therefore this study accessed the question, ‘why Chinese government initiative model for AFV promotion has been so poor?’ This study reviewed the transition process for AFV policies in China and made a structural analysis for three key policies since 2009. As a result the number of articles for related industries or factor endowments was relatively more than firm strategy or demand conditions. Also this study accessed the AFV strategy of Six SOEs from the perspective of social responsibility. Six SOEs have more concentrated on electric vehicle rather than hybrid vehicle with following the government leadership. However major EV or HEV models of them mostly were made by Joint Ventures being under control of foreign makers and the JVs have actually controlled over AFV business. So the limitation of Chinese government initiative model resulted from supplier-centric approach with targeting for public transportation and institution consumer, and it caused a failure to create the demand conditions of general customers.

  17. ALTERNATIVE REMEDIATION TECHNOLOGY STUDY FOR GROUNDWATER TREATMENT AT 200-PO-1 OPERABLE UNIT AT HANFORD SITE

    Energy Technology Data Exchange (ETDEWEB)

    DADO MA

    2008-07-31

    This study focuses on the remediation methods and technologies applicable for use at 200-PO-I Groundwater Operable Unit (OU) at the Hanford Site. The 200-PO-I Groundwater au requires groundwater remediation because of the existence of contaminants of potential concern (COPC). A screening was conducted on alternative technologies and methods of remediation to determine which show the most potential for remediation of groundwater contaminants. The possible technologies were screened to determine which would be suggested for further study and which were not applicable for groundwater remediation. COPCs determined by the Hanford Site groundwater monitoring were grouped into categories based on properties linking them by remediation methods applicable to each COPC group. The screening considered the following criteria. (1) Determine if the suggested method or technology can be used for the specific contaminants found in groundwater and if the technology can be applied at the 200-PO-I Groundwater au, based on physical characteristics such as geology and depth to groundwater. (2) Evaluate screened technologies based on testing and development stages, effectiveness, implementability, cost, and time. This report documents the results of an intern research project conducted by Mathew Dado for Central Plateau Remediation in the Soil and Groundwater Remediation Project. The study was conducted under the technical supervision of Gloria Cummins and management supervision of Theresa Bergman and Becky Austin.

  18. Alternative Exercise Technologies to Fight against Sarcopenia at Old Age: A Series of Studies and Review

    Directory of Open Access Journals (Sweden)

    Wolfgang Kemmler

    2012-01-01

    Full Text Available The most effective physiologic mean to prevent sarcopenia and related muscle malfunction is a physically active lifestyle, or even better, physical exercise. However, due to time constraints, lack of motivation, or physical limitations, a large number of elderly subjects are either unwilling or unable to perform conventional workouts. In this context, two new exercise technologies, whole-body vibration (WBV and whole-body electromyostimulation (WB-EMS, may exhibit a save, autonomous, and efficient alternative to increase or maintain muscle mass and function. Regarding WB-EMS, the few recent studies indeed demonstrated highly relevant effects of this technology on muscle mass, strength, and power parameters at least in the elderly, with equal or even higher effects compared with conventional resistance exercise. On the contrary, although the majority of studies with elderly subjects confirmed the positive effect of WBV on strength and power parameters, a corresponding relevant effect on muscle mass was not reported. However, well-designed studies with adequate statistical power should focus more intensely on this issue.

  19. AN EMPIRICAL STUDY OF ECONOMIC ALTERNATIVES FOR THE ELDERLY IN ROMANIA

    Directory of Open Access Journals (Sweden)

    Podoabă Lucia

    2013-04-01

    Full Text Available This paper is part of an applied, broad, based popular empirical procedures (such as natural observation scientific research. The positivist research methodology used was based on consensual-inductive system (Locke, which is why we studied different specialists’ opinions on the use of EU funds for the elderly in Romania or employer contributions to voluntary private funds, necessary to formulate the problem of generating relevant information. The used research strategies were the comparative and longitudinal ones, as we analyzed the time evolution in time of the number of pensioners and employees in Romania, in the main time with the EU funding for the elderly, to determine Romania's concrete economic alternatives to support this category of populations. Causality assumptions about the relationship efficient use of EU funds-beneficiaries was inductively built in this paper (by analyzing the European funds management issue in Romania, causally (by cause and effect explanation of the studied phenomenon, deductively, logically and subjectively (on the basis of existence and perpetuation of fund premise conflict between strategic absorption of European funds and regional development. The qualitative approach of the phenomenon studied was made by collecting information (using the mediate data collection technique has allowed relevant findings and practical solutions necessary for all those involved in this concerted action for the elderly, which affects us all.

  20. Use of multi-criteria decision analysis in regulatory alternatives analysis: a case study of lead free solder.

    Science.gov (United States)

    Malloy, Timothy F; Sinsheimer, Peter J; Blake, Ann; Linkov, Igor

    2013-10-01

    Regulators are implementing new programs that require manufacturers of products containing certain chemicals of concern to identify, evaluate, and adopt viable, safer alternatives. Such programs raise the difficult question for policymakers and regulated businesses of which alternatives are "viable" and "safer." To address that question, these programs use "alternatives analysis," an emerging methodology that integrates issues of human health and environmental effects with technical feasibility and economic impact. Despite the central role that alternatives analysis plays in these programs, the methodology itself is neither well-developed nor tailored to application in regulatory settings. This study uses the case of Pb-based bar solder and its non-Pb-based alternatives to examine the application of 2 multi-criteria decision analysis (MCDA) methods to alternatives analysis: multi-attribute utility analysis and outranking. The article develops and evaluates an alternatives analysis methodology and supporting decision-analysis software for use in a regulatory context, using weighting of the relevant decision criteria generated from a stakeholder elicitation process. The analysis produced complete rankings of the alternatives, including identification of the relative contribution to the ranking of each of the highest level decision criteria such as human health impacts, technical feasibility, and economic feasibility. It also examined the effect of variation in data conventions, weighting, and decision frameworks on the outcome. The results indicate that MCDA can play a critical role in emerging prevention-based regulatory programs. Multi-criteria decision analysis methods offer a means for transparent, objective, and rigorous analysis of products and processes, providing regulators and stakeholders with a common baseline understanding of the relative performance of alternatives and the trade-offs they present.

  1. Full receiver operating characteristic curve estimation using two alternative forced choice studies.

    Science.gov (United States)

    Massanes, Francesc; Brankov, Jovan G

    2016-01-01

    Task-based medical image quality is typically measured by the degree to which a human observer can perform a diagnostic task in a psychophysical human observer study. During a typical study, an observer is asked to provide a numerical score quantifying his confidence as to whether an image contains a diagnostic marker or not. Such scores are then used to measure the observers' diagnostic accuracy, summarized by the receiver operating characteristic (ROC) curve and the area under ROC curve. These types of human studies are difficult to arrange, costly, and time consuming. In addition, human observers involved in this type of study should be experts on the image genre to avoid inconsistent scoring through the lengthy study. In two-alternative forced choice (2AFC) studies, known to be faster, two images are compared simultaneously and a single indicator is given. Unfortunately, the 2AFC approach cannot lead to a full ROC curve or a set of image scores. The aim of this work is to propose a methodology in which multiple rounds of the 2AFC studies are used to re-estimate an image confidence score (a.k.a. rating, ranking) and generate the full ROC curve. In the proposed approach, we treat image confidence score as an unknown rating that needs to be estimated and 2AFC as a two-player match game. To achieve this, we use the ELO rating system, which is used for calculating the relative skill levels of players in competitor-versus-competitor games such as chess. The proposed methodology is not limited to ELO, and other rating methods such as TrueSkill™, Chessmetrics, or Glicko can be also used. The presented results, using simulated data, indicate that a full ROC curve can be recovered using several rounds of 2AFC studies and that the best pairing strategy starts with the first round of pairing abnormal versus normal images (as in the classical 2AFC approach) followed by a number of rounds using random pairing. In addition, the proposed method was tested in a pilot human

  2. Model‐Based Assessment of Alternative Study Designs in Pediatric Trials. Part II: Bayesian Approaches

    Science.gov (United States)

    Smania, G; Baiardi, P; Ceci, A; Magni, P

    2016-01-01

    This study presents a pharmacokinetic‐pharmacodynamic based clinical trial simulation framework for evaluating the performance of a fixed‐sample Bayesian design (BD) and two alternative Bayesian sequential designs (BSDs) (i.e., a non‐hierarchical (NON‐H) and a semi‐hierarchical (SEMI‐H) one). Prior information was elicited from adult trials and weighted based on the expected similarity of response to treatment between the pediatric and adult populations. Study designs were evaluated in terms of: type I and II errors, sample size per arm (SS), trial duration (TD), and estimate precision. No substantial differences were observed between NON‐H and SEMI‐H. BSDs require, on average, smaller SS and TD compared to the BD, which, on the other hand, guarantees higher estimate precision. When large differences between children and adults are expected, BSDs can return very large SS. Bayesian approaches appear to outperform their frequentist counterparts in the design of pediatric trials even when little weight is given to prior information from adults. PMID:27530374

  3. An alternative to nerve repair using an antioxidant compound: a histological study in rats.

    Science.gov (United States)

    Salles, Marcos B; Gehrke, Sergio A; Koo, Samuel; Allegrini, Sergio; Rogero, Sizue O; Ikeda, Tamiko I; Cruz, Áurea S; Shinohara, Elio H; Yoshimoto, Marcelo

    2015-01-01

    The fascicular composition and organisation of the inferior alveolar nerve (IAN) were determined to confirm the microarchitecture of the IAN bundles into each of the mandibular teeth, including the composition of the mental nerve. The aim of this study was to evaluate peripheral nerve repair after the application of an antioxidant compound to the damaged nerve tissue to elevate the concentration and bioavailability of elements capable of favouring tissue repair. Twenty-five Wistar rats were divided into groups: The Control 1 (Ctl 1) (n = 5) animals had the ischiatic nerve exposed with no suture injury and were sacrificed at 30 days post-operatively. The Control 2 (Ctl 2) (n = 10) animals had the ischiatic nerve exposed, and the nerve was injured using suture in three distinct regions. In the experimental (Exp) animals (n = 10), an antioxidant organic compound was applied to the nerve injury site. The animals with nerve injury (Ctl2 and Exp group) were sacrificed at 15 and 30 days post-operatively. The histological analysis showed less degeneration in the Exp group at 15 and 30 days post-operatively. Nerve neoformation forming a connection between the distal and proximal suture sites was observed in the experimental group. This study presented an alternative to nerve repair using an antioxidant compound. PMID:25578694

  4. Subcritical monitoring studies in BZD/2 using alternative absorber compositions and a localised neutron source

    International Nuclear Information System (INIS)

    A series of supplementary subcritical monitoring studies has been carried out in the Single Annular Core BZD/2. The first part concerned the use of alternative absorber compositions: 40 % enriched B4C and Eu2O3. The worth of the 40 % enriched B4C absorber relative to the naturally enriched one was found to be significantly lower than for the corresponding measurements in the conventional core BZB (1.197 versus 1.259). Although an influence of the harder spectrum in BZD is likely, the results of similar studies in BZC seem to contradict this assumption. Within the experimental errors, the worth of the Eu2O3 absorber relative to natural B4C agrees with that found in BZB. As in previous investigations, diffusion theory calculations were found to overestimate the worth of the 40 % enriched B4C absorber relative to the natural one by several percent. The worth of Eu2O3 relative to B4C-nat was again severely underpredicted. In a second series of experiments, a localised neutron source (Cf-252) was introduced into the core. For the two absorber arrays established in the presence of the source, the MSM analysis produced reactivities, which agree within about 0.5 % relative with those, obtained from previous measurements of these arrays without the localised source. This confirms the satisfactory performance of the MSM technique even in a strongly decoupled annular system with very irregular source distribution

  5. a Study on the Alternative Technology Using Unsm Instead of the Presetting Method for Torsion Bar

    Science.gov (United States)

    Suh, Chang-Min; Kim, Min-Ho; Baek, Un-Bong; Pyoun, Young-Sik; Kim, Chang-Sik; Chi, Chong-Ho

    The torsion bar must be changed periodically due to its lack of durability and a phenomenon related to stress relaxation. Therefore technical development regarding the torsion bar's durability is urgently needed. In order to improve the fatigue life and durability of the dynamic components, new surface treatment technology such as ultrasonic shot peening, deep rolling, laser shock peening, etc. are developing widely. In this study, Ultrasonic Nanocrystal Surface Modification (UNSM) technology is applied as an advanced one to replace the presetting method (PM). UNSM and PM technology also induced the compressive residual stress on the surface layer of the torsion bar, which is the main improvement factor of fatigue life. DIN17221 material as a new MIL specification of torsion bar and SCM440 (as an alternative one to a old MIL-DTL-62567C) were processed with the UNSM technology to obtain the basic data and compare it between two, and then torsion fatigue tests of two materials were carried out to obtain the characteristics of torsion fatigue in this study.

  6. Alternating current cloud point extraction on a microchip: a comprehensive study.

    Science.gov (United States)

    Sasaki, Naoki; Takemura, Azusa; Sato, Kae

    2012-11-01

    We present a comprehensive study of alternating current cloud point extraction (ACPE) on a microchip. ACPE is an extraction technique for preconcentration of membrane-associated biomolecules. To characterize and optimize ACPE, we carried out ACPE experiments under various experimental conditions including amplitude and frequency of applied voltages, flow velocity, and concentration of surfactant, analyte, and salt. We found that ACPE has an amplitude threshold (15 V(p-p)), above which the extraction was more efficient. The dependence of the extraction on frequency (>5 MHz) was insignificant. Efficient extraction was achieved when the velocity of the test solution was 0.10∼0.67 mm s⁻¹ and the concentration of surfactant was 0.10∼1.0%. In contrast, the extraction was independent of the concentration of analytes (0.20∼20 μmol dm⁻³). The technique was applicable to solutions with a salt concentration of 0.050∼0.15 mol dm⁻³ under temperature control of the devices. Solution temperature in ACPE was also studied. These results provide guidelines for use of the ACPE technique in microfluidic chemical and biochemical analyses.

  7. Alternative energies; Energies alternatives

    Energy Technology Data Exchange (ETDEWEB)

    Bonal, J.; Rossetti, P

    2007-07-01

    The earth took millions years to made the petroleum, the gas the coal and the uranium. Only a few centuries will be needed to exhaust these fossil fuels and some years to reach expensive prices. Will the wold continue on this way of energy compulsive consumption? The renewable energies and some citizen attitudes are sufficient to break this spiral. This book proposes to discuss these alternative energies. It shows that this attitude must be supported by the government. It takes stock on the more recent information concerning the renewable energies. it develops three main points: the electricity storage, the housing and the transports. (A.L.B.)

  8. Atmospheric Photochemistry Studies of Pollutant Emissions from Transportation Vehicles Operating on Alternative Fuels

    Energy Technology Data Exchange (ETDEWEB)

    Jeffries, H.; Sexton, K.; Yu, J.

    1998-07-01

    This project was undertaken with the goal of improving our ability to predict the changes in urban ozone resulting from the widespread use of alternative fuels in automobiles. This report presents the results in detail.

  9. Theoretical and experimental studies on combustion of alternative fuels in cement kilns

    OpenAIRE

    Axelsen, Ernst Petter

    2002-01-01

    In this thesis, the utilization of alternative fuels for NOx reduction by means of reburning and advanced reburning is sonsidered. Laboratory experiments, full-scale experiments and computational fluid dynamic (CFD) simulations are the basis of the thesis.The goal of the work was to characterize alternative fuels used in cement kilns, with focus on the processes taking place in the precalciner of the cement kiln. To facilitate testing under controlled process conditons, a lab-scale circulatin...

  10. Alternative Chemical Cleaning Methods for High Level Waste Tanks: Simulant Studies

    Energy Technology Data Exchange (ETDEWEB)

    Rudisill, T. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); King, W. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Hay, M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Jones, D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-11-19

    Solubility testing with simulated High Level Waste tank heel solids has been conducted in order to evaluate two alternative chemical cleaning technologies for the dissolution of sludge residuals remaining in the tanks after the exhaustion of mechanical cleaning and sludge washing efforts. Tests were conducted with non-radioactive pure phase metal reagents, binary mixtures of reagents, and a Savannah River Site PUREX heel simulant to determine the effectiveness of an optimized, dilute oxalic/nitric acid cleaning reagent and pure, dilute nitric acid toward dissolving the bulk non-radioactive waste components. A focus of this testing was on minimization of oxalic acid additions during tank cleaning. For comparison purposes, separate samples were also contacted with pure, concentrated oxalic acid which is the current baseline chemical cleaning reagent. In a separate study, solubility tests were conducted with radioactive tank heel simulants using acidic and caustic permanganate-based methods focused on the “targeted” dissolution of actinide species known to be drivers for Savannah River Site tank closure Performance Assessments. Permanganate-based cleaning methods were evaluated prior to and after oxalic acid contact.

  11. Hypersensitivity reaction studies of a polyethoxylated castor oil-free, liposome-based alternative paclitaxel formulation.

    Science.gov (United States)

    Wang, Hongbo; Cheng, Guang; Du, Yuan; Ye, Liang; Chen, Wenzhong; Zhang, Leiming; Wang, Tian; Tian, Jingwei; Fu, Fenghua

    2013-03-01

    The commercial drug paclitaxel (Taxol) may introduce hypersensitivity reactions associated with the polyethoxylated castor oil-ethanol solvent. To overcome these problems, we developed a polyethoxylated castor oil-free, liposome-based alternative paclitaxel formulation, known as Lipusu. In this study, we performed in vitro and in vivo experiments to compare the safety profiles of Lipusu and Taxol, with special regard to hypersensitivity reactions. First, Swiss mice were used to determine the lethal dosages, and then to evaluate hypersensitivity reactions, followed by histopathological examination and enzyme-linked immunosorbent assays (ELISAs) of serum SC5b-9 and lung histamine. Additionally, healthy human serum was used to analyze in vitro complement activation. Finally, an MTT assay was used to determine the in vitro anti-proliferation activity. Our data clearly showed that Lipusu displayed a much higher safety margin and did not induce hypersensitivity or hypersensitivity-related lung lesions, which may be associated with the fact that Lipusu did not activate complement or increase histamine release in vivo. Moreover, Lipusu did not promote complement activation in healthy human serum in vitro, and demonstrated anti-proliferative activity against human cancer cells, similar to that of Taxol. Therefore, the improved formulation of paclitaxel, which exhibited a much better safety profile and comparable cytotoxic activity to Taxol, may bring a number of benefits to cancer patients.

  12. Spectroscopic Study of Band Alignment in Alternative High-k MOS Dielectric Stacks

    Science.gov (United States)

    Bersch, E.; Rangan, S.; Garfunkel, E.; Bartynski, R. A.

    2007-03-01

    The study of high-k dielectrics and metal gate electrodes is critical to next generation MOSFETs. We have measured the band offsets of alternative MOS stacks using photoemission and inverse photoemission in the same chamber as well as synchrotron photoemission. At Rutgers, we have measured the valence and conduction band densities of states (DOS) and edges with UV photoemission and inverse photoemission, respectively, in situ. Using synchrotron photoemission we have measured the core level positions as well as the valence band DOS of clean and metallized dielectric/Si systems. The measurement of the chemical shifts of the core levels upon metallization enables us to evaluate the conduction band offset at the metal/dielectric interface. For Hf(x)Si(1-x)O(2), we find the conduction band offset (CBO) does not change as x is varied from 1 to 0.8, but the valence band offset increases by 0.4 eV. Titanium, aluminum and ruthenium were chosen as gate metals because of their prospective use as low and high workfunction metals in dual metal gate CMOS devices. We measured the CBO for the Ti, Al and Ru/Hf(x)Si(1-x)O(2) interfaces and found barriers involving Ti and Ru to be in good agreement with the interface gap state model, whereas the barrier involving Al deviated substantially from it due to the formation of an AlO(X) layer at the interface.

  13. Alternatives to neonicotinoid insecticides for pest control: case studies in agriculture and forestry.

    Science.gov (United States)

    Furlan, Lorenzo; Kreutzweiser, David

    2015-01-01

    Neonicotinoid insecticides are widely used for control of insect pests around the world and are especially pervasive in agricultural pest management. There is a growing body of evidence indicating that the broad-scale and prophylactic uses of neonicotinoids pose serious risks of harm to beneficial organisms and their ecological function. This provides the impetus for exploring alternatives to neonicotinoid insecticides for controlling insect pests. We draw from examples of alternative pest control options in Italian maize production and Canadian forestry to illustrate the principles of applying alternatives to neonicotinoids under an integrated pest management (IPM) strategy. An IPM approach considers all relevant and available information to make informed management decisions, providing pest control options based on actual need. We explore the benefits and challenges of several options for management of three insect pests in maize crops and an invasive insect pest in forests, including diversifying crop rotations, altering the timing of planting, tillage and irrigation, using less sensitive crops in infested areas, applying biological control agents, and turning to alternative reduced risk insecticides. Continued research into alternatives is warranted, but equally pressing is the need for information transfer and training for farmers and pest managers and the need for policies and regulations to encourage the adoption of IPM strategies and their alternative pest control options.

  14. Rural Australian community pharmacists' views on complementary and alternative medicine: a pilot study

    Directory of Open Access Journals (Sweden)

    Willis Jon A

    2011-10-01

    Full Text Available Abstract Background Complementary and alternative medicines (CAMs are being used increasingly across the world. In Australia, community pharmacists are a major supplier of these products but knowledge of the products and interactions with other medicines is poor. Information regarding the use of CAMs by metropolitan pharmacists has been documented by the National Prescribing Service (NPS in Australia but the views of rural/regional community pharmacists have not been explored. The aim of this pilot study was to explore the knowledge, attitudes and information seeking of a cohort of rural community pharmacists towards CAMs and to compare the findings to the larger NPS study. Methods A cross sectional self-administered postal questionnaire was mailed to all community pharmacists in one rural/regional area of Australia. Using a range of scales, data was collected regarding attitudes, knowledge, information seeking behaviour and demographics. Results Eighty eligible questionnaires were returned. Most pharmacists reported knowing that they should regularly ask consumers if they are using CAMs but many lacked the confidence to do so. Pharmacists surveyed for this study were more knowledgeable in regards to side effects and interactions of CAMs than those in the NPS survey. Over three quarters of pharmacists surveyed reported sourcing CAM information at least several times a month. The most frequently sought information was drug interactions, dose, contraindications and adverse effects. A variety of resources were used to source information, the most popular source was the internet but the most useful resource was CAM text books. Conclusions Pharmacists have varied opinions on the use of CAMs and many lack awareness of or access to good quality CAMs information. Therefore, there is a need to provide pharmacists with opportunities for further education. The data is valuable in assisting interested stakeholders with the development of initiatives to

  15. Soy use and vasomotor symptoms: Soy Estrogen Alternative follow-up study

    Directory of Open Access Journals (Sweden)

    Mara Z Vitolins

    2010-11-01

    Full Text Available Mara Z Vitolins1, L Douglas Case1, Timothy M Morgan1, Margaret A Miller2, Gregory L Burke11Division of Public Health Sciences, Wake Forest University Health Sciences, Winston-Salem, North Carolina, 2National Center for Toxicology Research, Food and Drug Administration Rockville, Maryland, USAPurpose: To evaluate vasomotor symptoms and soy and hormone therapy use in women who had previously participated in the Soy Estrogen Alternative (SEA study, a trial conducted to compare the effects of soy protein supplements containing differing levels of isoflavones on menopausal symptoms, chronic disease risk factors, and health-related quality of life in perimenopausal and postmenopausal women.Participants and methods: Two years after the SEA study ended participants were recontacted to complete questionnaires to quantify their health status, medications, menopausal symptoms, and their use of hormone therapy and soy-based foods and supplements. Participants were also asked to record vasomotor symptoms for seven days.Results: Surveys were collected from 182 of the 241 participants who had been enrolled in the SEA study (76% response rate. Women were 55 ± 2.8 years of age, well educated (80% more than high school, and 93% reported good to excellent health. All but six reported experiencing at least one menopausal symptom, and 56% reported one or more hot flashes on one or more days. Eighty-one women (45% continued to use soy for menopausal symptom relief, and 58 (32% were using hormone therapy. Women taking hormone therapy were experiencing fewer and less severe hot flashes than those who were not taking hormone therapy (P < 0.001; hot flash frequency and severity did not differ significantly between those who did and did not use soy, after controlling for hormone therapy use.Conclusion: Most participants reported they were still experiencing menopausal symptoms. Additionally, half of the most symptomatic women (not taking hormone therapy were still

  16. Study of Gasohol as Alternative Fuel for Gasoline Substitution: Characteristics and Performances

    Directory of Open Access Journals (Sweden)

    Bardi Murachman

    2014-12-01

    Full Text Available Gasohol is a mixture of premium petrol (gasoline with alcohol, in this case ethanol. The use of gasohol can reduce fuel consumption without having to modify the existing engine. Therefore, this research is conducted to study the characteristics and performance of gasohol in various mixing ratios, which includes analysis of physical properties and the use of gasohol in the machine. Results show that the addition of technical ethanol at 7.0169%v increases the value of gasohol vapor pressure on the value of 8.6682 psi (7.7 psi for regular gasoline. Gasohol with technical ethanol content above 30%v decreases vapor pressure, promotes phase separation, and causes a sharp drop in temperature from 40%v distillation. In term of corrosivity, gasohol with up to 50%v ethanol content has the same corrosion level with regular gasoline, which is corrosion level 1A. Based on gasohol characteristics test, it is known that gasohol with technical ethanol content below 20%v can be used as a fuel substitute for gasoline. Real-time performance test of gasohol in engines has shown that the addition of ethanol content in gasohol tend to increase the engine power at a certain compression ratio, but it also increases fuel consumption because the heat value of ethanol is lower than gasoline. Machine in gasohol with ethanol content below 20%v can operate smoothly without having to modify the engine. Based on the studies that have been done, gasohol in the range of 10%v ethanol content is well-functioned as a substitute for gasoline fuel and meets fuel specifications required by the General Director of Oil and Gas. The feasibility of using gasohol as an alternative fuel can be studied further.

  17. Alternative additives; Alternative additiver

    Energy Technology Data Exchange (ETDEWEB)

    2007-08-15

    In this project a number of industrial and agricultural waste products have been characterised and evaluated in terms of alkali-getter performance. The intended use is for biomass-fired power stations aiming at reducing corrosion or slagging related problems. The following products have been obtained, characterised and evaluated: 1) Brewery draff 2) Danish de-gassed manure 3) Paper sludge 4) Moulding sand 5) Spent bleaching earth 6) Anorthosite 7) Sand 8) Clay-sludge. Most of the above alternative additive candidates are deemed unsuitable due to insufficient chemical effect and/or expensive requirements for pre-treatment (such as drying and transportation). 3 products were selected for full-scale testing: de-gassed manure, spent bleaching earth and clay slugde. The full scale tests were undertaken at the biomass-fired power stations in Koege, Slagelse and Ensted. Spent bleaching earth (SBE) and clay sludge were the only tested additive candidates that had a proven ability to react with KCl, to thereby reduce Cl-concentrations in deposits, and reduce the deposit flux to superheater tubes. Their performance was shown to nearly as good as commercial additives. De-gassed manure, however, did not evaluate positively due to inhibiting effects of Ca in the manure. Furthermore, de-gassed manure has a high concentration of heavy metals, which imposes a financial burden with regard to proper disposal of the ash by-products. Clay-sludge is a wet clay slurring, and drying and transportation of this product entails substantial costs. Spent bleaching does not require much pre-treatment and is therefore the most promising alternative additive. On the other hand, bleaching earth contains residual plant oil which means that a range of legislation relating to waste combustion comes into play. Not least a waste combustion fee of 330 DKK/tonne. For all alternative (and commercial) additives disposal costs of the increase ash by-products represents a significant cost. This is

  18. Developing alternative indices of reproductive potential for use in fisheries management : Case studies for stocks spanning an information gradient

    DEFF Research Database (Denmark)

    Marshall, C.T.; O'Brien, L.; Tomkiewicz, Jonna;

    2003-01-01

    sufficient data to reconstruct a time series of total eggproduction (TEP), whereas, the remaining stocks were limited to estimating proxies for stockreproductive potential. For some of the case studies the alternative indices explained a higheramount of recruitment variation than did SSB. Other case studies...

  19. Conceptual design report: Nuclear materials storage facility renovation. Part 6, Alternatives study

    International Nuclear Information System (INIS)

    The Nuclear Materials Storage Facility (NMSF) at the Los Alamos National Laboratory (LANL) was a Fiscal Year (FY) 1984 line-item project completed in 1987 that has never been operated because of major design and construction deficiencies. This renovation project, which will correct those deficiencies and allow operation of the facility, is proposed as an FY 97 line item. The mission of the project is to provide centralized intermediate and long-term storage of special nuclear materials (SNM) associated with defined LANL programmatic missions and to establish a centralized SNM shipping and receiving location for Technical Area (TA)-55 at LANL. Based on current projections, existing storage space for SNM at other locations at LANL will be loaded to capacity by approximately 2002. This will adversely affect LANUs ability to meet its mission requirements in the future. The affected missions include LANL's weapons research, development, and testing (WRD ampersand T) program; special materials recovery; stockpile survelliance/evaluation; advanced fuels and heat sources development and production; and safe, secure storage of existing nuclear materials inventories. The problem is further exacerbated by LANL's inability to ship any materials offsite because of the lack of receiver sites for material and regulatory issues. Correction of the current deficiencies and enhancement of the facility will provide centralized storage close to a nuclear materials processing facility. The project will enable long-term, cost-effective storage in a secure environment with reduced radiation exposure to workers, and eliminate potential exposures to the public. This report is organized according to the sections and subsections outlined by Attachment 111-2 of DOE Document AL 4700.1, Project Management System. It is organized into seven parts. This document, Part VI - Alternatives Study, presents a study of the different storage/containment options considered for NMSF

  20. Final Technical Report for Alternative Fuel Source Study-An Energy Efficient and Environmentally Friendly Approach

    Energy Technology Data Exchange (ETDEWEB)

    Zee, Ralph [Auburn University, AL (United States); Schindler, Anton [Auburn University, AL (United States); Duke, Steve [Auburn University, AL (United States); Burch, Thom [Auburn University, AL (United States); Bransby, David [Auburn University, AL (United States); Stafford, Don [Lafarge North America, Inc., Alpharetta, GA (United States)

    2010-08-31

    The objective of this project is to conduct research to determine the feasibility of using alternate fuel sources for the production of cement. Successful completion of this project will also be beneficial to other commercial processes that are highly energy intensive. During this report period, we have completed all the subtasks in the preliminary survey. Literature searches focused on the types of alternative fuels currently used in the cement industry around the world. Information was obtained on the effects of particular alternative fuels on the clinker/cement product and on cement plant emissions. Federal regulations involving use of waste fuels were examined. Information was also obtained about the trace elements likely to be found in alternative fuels, coal, and raw feeds, as well as the effects of various trace elements introduced into system at the feed or fuel stage on the kiln process, the clinker/cement product, and concrete made from the cement. The experimental part of this project involves the feasibility of a variety of alternative materials mainly commercial wastes to substitute for coal in an industrial cement kiln in Lafarge NA and validation of the experimental results with energy conversion consideration.

  1. Preconceptual Feasibility Study to Evaluate Alternative Means to Produce Plutonium-238

    Energy Technology Data Exchange (ETDEWEB)

    John D. Bess; Matthew S. Everson

    2013-02-01

    There is currently no large-scale production of 238Pu in the United States. Feasibility studies were performed at the Idaho National Laboratory to assess the capability of developing alternative 238Pu production strategies. Initial investigations indicate potential capability to provision radioisotope-powered systems for future space exploration endeavors. For the short term production of 238Pu, sealed canisters of dilute 237Np solution in nitric acid could be irradiated in the Advanced Test Reactor (ATR). Targets in the large and medium “I” positions of the ATR were irradiated over a simulated period of 306 days and analyzed using MCNP5 and ORIGEN2.2. Approximately 0.5 kg of 238Pu could be produced annually in the ATR with purity greater than 92%. Optimization of the irradiation cycles could further increase the purity to greater than 98%. Whereas the typical purity of space batteries is between 80 to 85%, the higher purity 238Pu produced in the ATR could be blended with existing lower-purity inventory to produce useable material. Development of irradiation methods in the ATR provides the fastest alterative to restart United States 238Pu production. The analysis of 238Pu production in the ATR provides the technical basis for production using TRIGA® (Training, Research, Isotopes, General Atomics) nuclear reactors. Preliminary analyses envisage a production rate of approximately 0.7 kg annually using a single dedicated 5-MW TRIGA reactor with continuous flow loops to achieve high purity product. Two TRIGA reactors represent a robust means of providing at over 1 kg/yr of 238Pu annually using dilute solution targets of 237Np in nitric acid. Further collaboration and optimization of reactor design, radiochemical methods, and systems analyses would further increase annual 238Pu throughput, while reducing the currently evaluated reactor requirements.

  2. Use of complementary alternative medicine for low back pain consulting in general practice: a cohort study

    Directory of Open Access Journals (Sweden)

    Baum Erika

    2007-12-01

    Full Text Available Abstract Background Although back pain is considered one of the most frequent reasons why patients seek complementary and alternative medical (CAM therapies little is known on the extent patients are actually using CAM for back pain. Methods This is a post hoc analysis of a longitudinal prospective cohort study embedded in a RCT. General practitioners (GPs recruited consecutively adult patients presenting with LBP. Data on physical function, on subjective mood, and on utilization of health services was collected at the first consultation and at follow-up telephone interviews for a period of twelve months Results A total of 691 (51% respectively 928 (69% out of 1,342 patients received one form of CAM depending on the definition. Local heat, massage, and spinal manipulation were the forms of CAM most commonly offered. Using CAM was associated with specialist care, chronic LBP and treatment in a rehabilitation facility. Receiving spinal manipulation, acupuncture or TENS was associated with consulting a GP providing these services. Apart from chronicity disease related factors like functional capacity or pain only showed weak or no association with receiving CAM. Conclusion The frequent use of CAM for LBP demonstrates that CAM is popular in patients and doctors alike. The observed association with a treatment in a rehabilitation facility or with specialist consultations rather reflects professional preferences of the physicians than a clear medical indication. The observed dependence on providers and provider related services, as well as a significant proportion receiving CAM that did not meet the so far established selection criteria suggests some arbitrary use of CAM.

  3. BIOINFORMATIC STUDIES ON STRUCTURAL ELEMENTS FOR THE REGULATION OF ALTERNATIVE OXIDASE (AOX) GENE ACTIVITIES

    OpenAIRE

    Xavier, Moisés Geraldes

    2007-01-01

    Trabalho de projecto de mestrado em Engenharia Informática, apresentado à Universidade de Lisboa, através da Faculdade de Ciências, 2007 Alternative Oxidase genes encode a small family of isoenzymes (enzymes with some differences but act in the same chemical reaction). AOX is present in plants, fungi, algae, some yeast, and was also found in some classes of the animal kingdom. The enzymes are responsible for an alternative pathway of respiration that is responsive to stress conditions but ...

  4. A pilot study of complementary and alternative medicine use in patients with fibromyalgia syndrome

    Directory of Open Access Journals (Sweden)

    Wall GC

    2007-12-01

    Full Text Available Fibromyalgia syndrome (FMS is a complex disorder, with primary symptoms of sleep disturbances, pain, and fatigue. FMS is one of the most common reasons for patient visits to a rheumatologist. Previous studies have suggested that complementary and alternative medicine (CAM use in patients with rheumatic diseases is common, but such data specific to FMS patients is limited. Objective: The following study sought to describe the prevalence of CAM use in a primary care practice of patients with FMS and assess whether these patients discuss CAM use with their physician, physician-extender, and/or pharmacist. Methods: A one-group cross-sectional survey design was implemented in a large, community-based, private physician practice of patients diagnosed with FMS. A self-administered questionnaire was distributed during clinic visits. It solicited information related to demographic characteristics; FMS-specific health background; whether CAM use had been discussed with a health care provider; and the “ever-use” of common types of CAM. Respondents returned the questionnaire via US mail in a postage-paid, self-addressed envelope. Results: A total of 115 surveys were distributed with 54 returned for analysis (47% completion rate. The sample was predominantly female, well educated and had a mean age of 55.6 years. All respondents were White. Most respondents (92.6% reported using some type of CAM. Exercise (92.2%, chiropractic treatment (48.1%, lifestyle and diet (45.8%, relaxation therapy (44.9%, and dietary and herbal supplements (36.5% were most commonly reported CAM therapies “ever-used” by respondents. Dietary and herbal supplements with the highest prevalence of “ever-use” were magnesium (19.2%, guaifenesin (11.5%, and methylsulfonylmethane (MSM (9.6%. Respondents most commonly discussed CAM with the clinic rheumatologist and the primary care physician (53.7% and 38.9%, respectively. Only 14.8% of respondents discussed CAM with a pharmacist

  5. Attitudes and perceptions of Australian pharmacy students towards Complementary and Alternative Medicine – a pilot study

    Directory of Open Access Journals (Sweden)

    Wallis Marianne

    2008-01-01

    Full Text Available Abstract Background With the increased usage of CAM worldwide comes the demand for its integration into health professional education. However, the incorporation of CAM into health professional curricula is handled quite differently by different institutions and countries. Furthermore, the evaluation of CAM curricula is complicated because students' ability to learn about CAM may be influenced by factors such as student's prior knowledge and motivation, together with the perceptions and attitudes of clinical preceptors. The study aimed to describe the attitudes, perceptions and beliefs of second, third and fourth year pharmacy students towards complementary and alternative medicine (CAM and to explore factors that might affect attitudes such as learning, preceptors and placements. Methods Pharmacy students from a University in South East Queensland, Australia participated in the study. The study consisted of a cross-sectional survey (n = 110 and semi-structured interviews (n = 9. Results The overall response rate for the survey was 75%, namely 50% (36/72 for second year, 77.3% (34/44 for third year and 97.6% (40/41 for fourth year students. Overall, 95.5% of pharmacy students believe that pharmacists should be able to advise patients about CAM and most (93.7% have used CAM prior to course enrolment. Students' attitudes to CAM are influenced by the use of CAM by family, friends and self, CAM training, lecturers and to a lesser degree by preceptors. The majority of pharmacy students (89.2% perceive education about CAM as a core and integral part of their professional degree and favour it over an additional postgraduate degree. However, they see a greater need for education in complementary medicines (such as herbal medicines, vitamins and minerals than for education in complementary therapies (such as acupuncture, meditation and bio-magnetism. Knowledge and educational input rationalised rather than marginalised students' attitudes towards CAM

  6. Alternative Policy Study: Environment and energy in Europe and Central Asia 1990-2010. Energy-related environmental impacts of policy scenarios GEO-2000 alternative policy study

    NARCIS (Netherlands)

    Vuuren DP van; Bakkes JA; MNV

    2000-01-01

    Deze GEO-2000 studie naar alternatief beleid voor Europa en Centraal Azie is gericht op energie als een belangrijke kracht achter milieuproblemen in de hele regio. De studie heeft betrekking op klimaatverandering, verzuring, zomersmog, stedelijke luchtverontreiniging en het risico op dodelijke o

  7. School-Wide Positive Behavior Support in an Alternative School Setting: A Case Study

    Science.gov (United States)

    Simonsen, Brandi; Britton, Lisa; Young, Dale

    2010-01-01

    Students with disabilities who display serious (e.g., dangerous) problem behaviors are frequently educated in alternative school settings. Although there is considerable research on intervention approaches (e.g., function-based support) to support individual students with challenging behaviors, there is a lack of research on schoolwide…

  8. A study of the diffusion of alternative fuel vehicles : An agent-based modeling approach

    NARCIS (Netherlands)

    Zhang, Ting; Gensler, Sonja; Garcia, Rosanna

    2011-01-01

    This paper demonstrates the use of an agent-based model (ABM) to investigate factors that can speed the diffusion of eco-innovations, namely alternative fuel vehicles (AFVs). The ABM provides the opportunity to consider the interdependencies inherent between key participants in the automotive indust

  9. MODELING AND DESIGN STUDY USING HFC-236EA AS AN ALTERNATIVE REFRIGERANT IN A CENTRIFUGAL COMPRESSOR

    Science.gov (United States)

    The report gives results of an investigation of the operation of a centrifugal compressor--part of a chlorofluorocarbon (CFC)-114 chiller installation--with the new refrigerant hydrofluorocarbon (HFC)-236ea, a proposed alternative to CFC-114. A large set of CFC-236ea operating da...

  10. The role of complementary and alternative medicine (CAM) in Germany - a focus group study of GPs.

    NARCIS (Netherlands)

    Joos, S.; Musselmann, B.; Miksch, A.; Rosemann, T.J.; Szecsenyi, J.

    2008-01-01

    BACKGROUND: There has been a marked increase in the use of complementary and alternative medicine (CAM) in recent years worldwide. In Germany, apart from 'Heilpraktiker' (= state-licensed, non-medical CAM practitioners), some general practitioners (GPs) provide CAM in their practices. This paper aim

  11. Study of alternative methods for the management of liquid scintillation counting wastes

    International Nuclear Information System (INIS)

    The Nuclear Engineering Waste Disposal Site in Richland, Washington, is the only radioactive waste disposal facility that will accept liquid scintillation counting wastes (LSCW) for disposal. That site is scheduled to discontinue receiving LSCW by the end of 1982. This document explores alternatives presently available for management of LSCW: evaporation, distillation, solidification, conversion, and combustion

  12. Technology mix alternatives with high shares of wind power and photovoltaics—case study for Spain

    International Nuclear Information System (INIS)

    The shift to a low carbon society is an issue of highest priority in the EU. For electricity generation, such a target counts with three main alternatives: renewable energies, nuclear power and carbon capture and storage. This paper focuses on the renewables’ alternative. Due to resource availability, a technology mix with a high share of PV and wind power is gaining increasing interest as a major solution for several EU member states and in part for the EU collectively to achieve decarbonization and energy security with acceptable costs. Due to their intermittency, the integration of high shares of PV and wind power in the electricity supply is challenging. This paper presents a techno-economic assessment of technology mix alternatives with a high share of PV and wind power in Spain, as an example. Thereby, the focus is on the option of increasing wind curtailment versus substituting rigid baseload generation in favor of the more flexible gas turbines and combined cycle gas turbines. - Highlights: ► The potential of power generation from renewable energy resources in the EU is illustrated. ► The LEC of the different technologies considered is calculated for today and future scenarios. ► An excel-based model for the technology mix assessment is applied using Spanish data. ► Technology mix alternatives with a high share of PV and wind power are assessed. ► The focus is on increasing wind curtailment vs. relying on more flexible power generation units.

  13. Evaluation of Colocasia esculenta Starch as an Alternative Tablet Excipient to Maize Starch: Assessment by Preformulation and Formulation Studies

    Directory of Open Access Journals (Sweden)

    Kusuma. R

    2015-01-01

    Full Text Available Starch isolated from Colocasia esculenta plant was studied as an alternative pharmaceutical excipient to maize and potato starch. The Colocasia esculenta starch has been evaluated by series of tests as mentioned in Indian Pharmacopoeia before being used for evaluation. It was tested along with maize and potato starch as an alternative excipient by performing battery of preformulation and formulation tests. The results obtained for Colocasia esculenta starch was comparable with maize starch and the Colocasia esculenta starch can be used as a pharmaceutical excipient in tablets preparation.

  14. Observational Learning from Animated Models: Effects of Studying-Practicing Alternation and Illusion of Control on Transfer

    NARCIS (Netherlands)

    Wouters, Pieter; Paas, Fred; Van Merriënboer, Jeroen

    2008-01-01

    Wouters, P. J. M., Paas, F., & Van Merriënboer, J. J. G. (2010). Observational learning from animated models: effects of studying-practicing alternation and illusion of control on transfer. Instructional Science, 38(1), 89-104. doi:10.1007/s11251-008-9079-0

  15. Parametric Optimization of Some Critical Operating System Functions--An Alternative Approach to the Study of Operating Systems Design

    Science.gov (United States)

    Sobh, Tarek M.; Tibrewal, Abhilasha

    2006-01-01

    Operating systems theory primarily concentrates on the optimal use of computing resources. This paper presents an alternative approach to teaching and studying operating systems design and concepts by way of parametrically optimizing critical operating system functions. Detailed examples of two critical operating systems functions using the…

  16. Alternative medicines for AIDS in resource-poor settings: insights from exploratory anthropological studies in Asia and Africa.

    Science.gov (United States)

    Hardon, Anita; Desclaux, Alice; Egrot, Marc; Simon, Emmanuelle; Micollier, Evelyne; Kyakuwa, Margaret

    2008-01-01

    The emergence of alternative medicines for AIDS in Asia and Africa was discussed at a satellite symposium and the parallel session on alternative and traditional treatments of the AIDSImpact meeting, held in Marseille, in July 2007. These medicines are heterogeneous, both in their presentation and in their geographic and cultural origin. The sessions focused on the role of these medications in selected resource poor settings in Africa and Asia now that access to anti-retroviral therapy is increasing. The aims of the sessions were to (1) identify the actors involved in the diffusion of these alternative medicines for HIV/AIDS, (2) explore uses and forms, and the way these medicines are given legitimacy, (3) reflect on underlying processes of globalisation and cultural differentiation, and (4) define priority questions for future research in this area. This article presents the insights generated at the meeting, illustrated with some findings from the case studies (Uganda, Senegal, Benin, Burkina Faso, China and Indonesia) that were presented. These case studies reveal the wide range of actors who are involved in the marketing and supply of alternative medicines. Regulatory mechanisms are weak. The efficacy claims of alternative medicines often reinforce a biomedical paradigm for HIV/AIDS, and fit with a healthy living ideology promoted by AIDS care programs and support groups. The AIDSImpact session concluded that more interdisciplinary research is needed on the experience of people living with HIV/AIDS with these alternative medicines, and on the ways in which these products interact (or not) with anti-retroviral therapy at pharmacological as well as psychosocial levels. PMID:18616794

  17. Alternative medicines for AIDS in resource-poor settings: Insights from exploratory anthropological studies in Asia and Africa

    Directory of Open Access Journals (Sweden)

    Simon Emmanuelle

    2008-07-01

    Full Text Available Abstract The emergence of alternative medicines for AIDS in Asia and Africa was discussed at a satellite symposium and the parallel session on alternative and traditional treatments of the AIDSImpact meeting, held in Marseille, in July 2007. These medicines are heterogeneous, both in their presentation and in their geographic and cultural origin. The sessions focused on the role of these medications in selected resource poor settings in Africa and Asia now that access to anti-retroviral therapy is increasing. The aims of the sessions were to (1 identify the actors involved in the diffusion of these alternative medicines for HIV/AIDS, (2 explore uses and forms, and the way these medicines are given legitimacy, (3 reflect on underlying processes of globalisation and cultural differentiation, and (4 define priority questions for future research in this area. This article presents the insights generated at the meeting, illustrated with some findings from the case studies (Uganda, Senegal, Benin, Burkina Faso, China and Indonesia that were presented. These case studies reveal the wide range of actors who are involved in the marketing and supply of alternative medicines. Regulatory mechanisms are weak. The efficacy claims of alternative medicines often reinforce a biomedical paradigm for HIV/AIDS, and fit with a healthy living ideology promoted by AIDS care programs and support groups. The AIDSImpact session concluded that more interdisciplinary research is needed on the experience of people living with HIV/AIDS with these alternative medicines, and on the ways in which these products interact (or not with anti-retroviral therapy at pharmacological as well as psychosocial levels.

  18. Experimental Study on Current Decay Characteristics of Persistent Current HTS Magnet by Alternating Magnetic Field

    Science.gov (United States)

    Park, Young Gun; Lee, Chang Young; Hwang, Young Jin; Lee, Woo Seung; Lee, Jiho; Jo, Hyun Chul; Chung, Yoon Do; Ko, Tae Kuk

    This paper deals with a current decay characteristics of a high temperature superconducting (HTS) magnet operated in persistent current mode (PCM). In superconducting synchronous machine applications such as linear synchronous motor (LSM), the superconducting coil is designed to operate in the PCM to obtain steady magnetic field with DC transport current. This superconducting magnet operates on a direct current, but it can be exposed to alternating magnetic field due to the armature winding. When the magnet is subjected to an external time-varying magnetic field, it is possible to result in a decay of the current in PCM system due to AC loss. In this research, a PCM system with armature coil which generates time-varying magnetic field was fabricated to verify current decay characteristics by external alternating magnetic field. The current decay rate was measured by using a hall sensor as functions of amplitude and frequency of armature coil.

  19. An Empirical Study of Islamic Equity as a Better Alternative during Crisis Using Multivariate GARCH DCC

    OpenAIRE

    Syed Aun R. Rizvi; ARSHAD , SHAISTA

    2014-01-01

    Risk Sharing is the core of the Islamic finance, the closest modern equivalent being equity investments. Through the decades of Islamic Finance development scholars have stressed on equity as the most beneficial financial mechanism while most accept modern joint-stock companies as quasi Mush rakah and Mu rabah forms, but this segment is still small in Islamic finance. Multitude of reasons contributes to it, primarily, the risk averseness and myth of equities as more risky alternate. This pape...

  20. A Statistical Analysis of the Nominative/Accusative Alternation in Japanese : A Preliminary Study

    OpenAIRE

    牧, 秀樹; 森島, 玉峰; マキ, ヒデキ; モリシマ, タマミ; Maki, Hideki; MORISHIMA, Tamami

    2004-01-01

    This paper investigates the Nominative/Accusative alternation exhibited by Japanese stative predicates, which in principle take a Nominative Object. Through a statistical analysis, we found two important facts : (I) that when an Accusative Object is moved to the sentence initial position, some types of stative predicates allow an Accusative Object, and (2) that when the sentence containing a stative predicate and an Accusative Object is embedded into a complex NP, all types of stative predica...

  1. Study on Plastic Coated Overburnt Brick Aggregate as an Alternative Material for Bituminous Road Construction

    OpenAIRE

    Sarkar, Dipankar; Pal, Manish; Sarkar, Ashoke K.

    2016-01-01

    There are different places in India where natural stone aggregates are not available for constructional work. Plastic coated OBBA can solve the problem of shortage of stone aggregate to some extent. The engineers are always encouraged to use locally available materials. The present investigation is carried out to evaluate the plastic coated OBBA as an alternative material for bituminous road construction. Shredded waste plastics are mixed with OBBA in different percentages as 0.38, 0.42, 0.46...

  2. Feasibility studies of actinide recycle in LMFBRs as a waste management alternative

    International Nuclear Information System (INIS)

    A strategy of actinide burnup in LMFBRs is being investigated as a waste management alternative to long term storage of high level nuclear waste. This strategy is being evaluated because many of the actinides in the waste from spent-fuel reprocessing have half-lives of thousands of years and an alternative to geological storage may be desired. From a radiological viewpoint, the actinides and their daughters dominate the waste hazard for decay times beyond about 400 years. Actinide burnup in LMFBRs may be an attractive alternative to geological storage because the actinides can be effectively transmuted to fission products which have significantly shorter half-lives. Actinide burnup in LMFBRs rather than LWRs is preferred because the ratio of fission reaction rate to capture reaction rate for the actinides is higher in an LMFBR, and an LMFBR is not so sensitive to the addition of the actinide isotopes. An actinide target assembly recycle scheme is evaluated to determine the effects of the actinides on the LMFBR performance, including local power peaking, breeding ratio, and fissile material requirements. Several schemes are evaluated to identify any major problems associated with reprocessing and fabrication of recycle actinide-containing assemblies. The overall efficiency of actinide burnout in LMFBRs is evaluated, and equilibrium cycle conditions are determined. It is concluded that actinide recycle in LMFBRs offers an attractive alternative to long term storage of the actinides, and does not significantly affect the performance of the host LMFBR. Assuming a 0.1 percent or less actinide loss during reprocessing, a 0.1 percent loss of less during fabrication, and proper recycle schemes, virtually all of the actinides produced by a fission reactor economy could be transmuted in fast reactors

  3. Utilization of Alternative Fuels in Cement Pyroprocessing : the Messebo Factory case study in Ethiopia

    OpenAIRE

    Ebuy Teka, Axumawi

    2015-01-01

    Energy costs and environmental standards encouraged cement manufacturers worldwide to evaluate to what extent conventional fuels (Furnace oil, Coal and Petcock) can be replaced by alternative fuels in cement production, i.e. biomass or processed waste materials like sewage sludge, MSW (municipal solid waste), Refuse Derived Fuels (RDF), Tire Derived Fuel (TDF), Plastic Derived Fuel (PDF), Biomass Derived Fuels (BDF), meat and bone meal (MBM), etc.  High temperature of >1500 C, long residen...

  4. Association of Health Literacy with Complementary and Alternative Medicine Use: A Cross-Sectional Study in Adult Primary Care Patients

    OpenAIRE

    Bains Sujeev S; Egede Leonard E

    2011-01-01

    Abstract Background In the United States, it is estimated that 40% of adults utilize complementary and alternative medicine (CAM) therapies. Recently, national surveys report that over 90 million adults have inadequate health literacy. To date, no study has assessed health literacy and its effect on CAM use. The primary objective of this study was to assess the relationship between health literacy and CAM use independent of educational attainment. Second objective was to evaluate the differen...

  5. Alternative Paths to Primary Education in Rural India: Five case studies of GAA-assisted educational projects

    OpenAIRE

    Jürgenmeyer, Clemens; Pappu, Rheka; Patil, Benazir; Weiland, Heribert

    2006-01-01

    This study analyses five educational projects in India that are supported by German Agro Action (GAA) and the European Union (EU) and are executed on the ground by Indian NGOs. Located in different geographical parts of India, the projects follow different ideological and pedagogical approaches. The study does not claim, especially given the size and diversity of Indian society, to represent the Indian educational situation as a whole. Rather, it intends to elucidate some alternative approach...

  6. Numerical study on the effects of the alternative structure geometries on the groundwater flow at the Olkiluoto site

    International Nuclear Information System (INIS)

    In the study the effects of the alternative hydrogeologic features on the groundwater flow are numerically modelled. The studied cases comprise the hydrogeologic features that were classified as possible in the bedrock model or implied either by the new interpretations of the results of the field investigations or the numerical groundwater flow analysis in preliminary site investigations. The preliminary site investigations for the radioactive waste disposal (Olkiluoto, Finland) were completed by the end of 1992. This report is a direct continuation of the earlier modeling work, which resolved the transmissivities and boundary conditions that yielded the calculated results agreeing the results of the field studies as well as possible. In this work, six alternative geometries are studied altogether. Each geometry is studied separately. The effects of the alternative geometries are evaluated by comparing the calculated results with the results of the field investigations. The field results consist of the measured fresh water head under the natural conditions and pumping test responses. (orig.) (29 refs., 24 figs., 8 tabs.)

  7. Copper canister with cast inner component. Amendment to project on Alternative Systems Study (PASS), SKB TR 93-04

    International Nuclear Information System (INIS)

    The Project on Alternative Systems Study, PASS, was described in a report dated october 1992. In the report, the reference repository concept KBS-3 is described together with three other alternatives. In the report several designs for fuel storage canisters are presented. This report describes a recently developed design for the inner component of the composite, steel and copper, canister which is the main alternative in the KBS-3-model. The new design will be manufactured by casting. A cast insert with inner walls eliminates the need for a stabilizing filler in the canister and guarantees that the fuel remains sub-critical during sufficient time in the repository. The cast insert is judged, to, in comparison with the steel tube alternative, lead to a considerably simplified process in the encapsulation plant and lower development and investment cost. Positive side effects of the design are that the mechanical strength is improved by a factor 2-3 and that the difficult filling operation is avoided in the encapsulation process. The drawbacks are higher weight and probably higher unit price for the empty canister

  8. Alternatives for Sustainable Development and Gender Equality: A Case Study from Sierra Leone

    OpenAIRE

    Lovetta Sesay, Fatmata

    2016-01-01

    Introduction It is generally accepted that women in developing countries live in a desperate economic situation. Yet there is little consensus as to what the problem is and therefore how it needs to be tackled. In the light of the “booming industry” of development agencies, it is time to evaluate how efficient and effective their work has been especially with their gender policies, and above all to evaluate the sustainability of programmes when agencies “poll out”. Alternatives for Sierra Leo...

  9. F- and H-Area Seepage Basins Water Treatment System Process Optimization and Alternative Chemistry Ion Exchange/Sorbent Material Screening Clearwell Overflow Study

    Energy Technology Data Exchange (ETDEWEB)

    Serkiz, S.M.

    2000-08-30

    This study investigated alternative ion exchange/sorbent materials and polishing chemistries designed to remove specific radionuclides not removed during the neutralization/precipitation/clarification process.

  10. Study on Spacing Threshold of Nonsubmerged Spur Dikes with Alternate Layout

    Directory of Open Access Journals (Sweden)

    Xiaomeng Cao

    2013-01-01

    Full Text Available This paper investigated the spacing threshold of nonsubmerged spur dikes with alternate layout to classify the impact scale of spur dikes. A mathematical model was built based on standard k-ε model, finite volume method (FVM, and rigid lid assumption and was verified by experimental data. According to dimensional analysis, three indices, that is, Fr (Froude number, B/b (channel width to dike length, and B/h (channel width to water depth, were identified as the influencing factors on the spacing threshold, based on which fifteen sets of conditions were simulated. The calculation results indicate that B/h is the most influencing parameter on Sc/b (spacing threshold to dike length, followed by B/b and Fr. A dimensionless empirical formula of spacing threshold is fitted by multivariate regression. The results of four sets of additional conditions illustrate that the generalization of empirical formula is satisfactory and the precision of interpolation is higher than that of extrapolation. Furthermore, the spacing threshold of alternate spur dikes is generally smaller than ipsilateral spur dikes.

  11. A Parallel World for the World Bank: A Case Study of Urgent: Evoke, An Educational Alternate Reality Game

    Directory of Open Access Journals (Sweden)

    David I. Waddington

    2013-01-01

    Full Text Available In 2010, the World Bank launched Urgent: Evoke, an alternate reality game. Conceived in response to the demands of African universities, the game was designed to promote the World Bank Institute’s vision of positive global change through social innovation, and made substantial use of Web 2.0 tools such as blogs, personal profiles, and social networks. This article offers a case study of Urgent: Evoke, divided into four sections: first, the potential to use video games as citizenship education tools is discussed; second, the unique game genre (alternate reality games into which Evoke falls is explained and some possible uses of this genre in higher education are examined; third, the functioning of the Evoke game world is explained; and fourth, the results of the Evoke educational project are assessed. The case study concludes with some commentary on Evoke’s ideological message, which those less sympathetic to capitalism may view as problematic.

  12. The Effect of the Japan 2011 Disaster on Nuclear and Alternative Energy Stocks Worldwide: An Event Study

    OpenAIRE

    Ferstl, Robert; Utz, Sebastian; Wimmer, Maximilian

    2012-01-01

    This event study investigates the impact of the Japanese nuclear disaster in Fukushima-Daiichi on the daily stock prices of French, German, Japanese, and U.S. nuclear utility and alternative energy firms. Hypotheses regarding the (cumulative) abnormal returns based on a three-factor model are analyzed through joint tests by multivariate regression models and bootstrapping. Our results show significant abnormal returns for Japanese nuclear utility firms during the one-week event window and the...

  13. Advanced Transportation System Studies. Technical Area 3: Alternate Propulsion Subsystems Concepts. Volume 3; Program Cost Estimates

    Science.gov (United States)

    Levack, Daniel J. H.

    2000-01-01

    The objective of this contract was to provide definition of alternate propulsion systems for both earth-to-orbit (ETO) and in-space vehicles (upper stages and space transfer vehicles). For such propulsion systems, technical data to describe performance, weight, dimensions, etc. was provided along with programmatic information such as cost, schedule, needed facilities, etc. Advanced technology and advanced development needs were determined and provided. This volume separately presents the various program cost estimates that were generated under three tasks: the F- IA Restart Task, the J-2S Restart Task, and the SSME Upper Stage Use Task. The conclusions, technical results , and the program cost estimates are described in more detail in Volume I - Executive Summary and in individual Final Task Reports.

  14. Use of Complementary and Alternative Medicine for Epileptic Children in Tehran: A Cross-Sectional Study (2009-2011

    Directory of Open Access Journals (Sweden)

    Seyed Hassan TONEKABONI

    2014-01-01

    Full Text Available How to Cite This Article: Tonekaboni Sh, Jafari Naeini S, Khajeh A, Yaghini O, Ghazavi A, Abdollah Gorji F. Use of Complementary and Alternative Medicine for Epileptic Children in Tehran: A Cross-Sectional Study (2009-2011. Iran J Child Neurol. 2014 Winter; 8(1:26-31.ObjectiveAlthough the use of Complementary and Alternative Medicine (CAM has been evaluated globally, there are few studies in our country on this subject. The purpose of this study was to determine the prevalence, pattern of use, parental sources of information, and benefits of CAM in epileptic children in Tehran.Materials & MethodsOne hundred thirty-three parents or relatives of epileptic children who were referred to outpatient clinics or admitted in neurologic ward of four major hospitals in Tehran, were interviewed by our researcher based on a structured questionnaire; from 2009 to 2010. The information obtained comprised the demographic data of patients and their parents, frequency and morphology of convulsions, the type and sources of CAM and finally, the benefits and adverseeffects of this practice.ResultsForty-four percent of the respondents had used CAM methods either alone or in combination with other methods. The most frequently used CAM was written prayers followed by oral herbs and special diets. CAM was mainly introduced to them by relatives. Only 16.7% of these parents had discussed this matter with their children’s physicians. No efficacy to control seizure was observed for most of these methods.ConclusionThis study showed that use of CAM in our study group is relatively common and may have a potentially hazardous role in the treatment process. So, it is necessary for physicians to have enough information about CAM practice in their patients. References:National Institutes of health. More than one third of US adults use complementary and alternative medicine, according to new government survey. [Serial online] 2004 (cited 2004 May 27. Available

  15. The Effect of the Japan 2011 Disaster on Nuclear and Alternative Energy Stocks Worldwide: An Event Study

    Directory of Open Access Journals (Sweden)

    Robert Ferstl

    2012-05-01

    Full Text Available This event study investigates the impact of the Japanese nuclear disaster in Fukushima-Daiichi on the daily stock prices of French, German, Japanese, and U.S. nuclear utility and alternative energy firms. Hypotheses regarding the (cumulative abnormal returns based on a three-factor model are analyzed through joint tests by multivariate regression models and bootstrapping. Our results show significant abnormal returns for Japanese nuclear utility firms during the one-week event window and the subsequent four-week post-event window. Furthermore, while French and German nuclear utility and alternative energy stocks exhibit significant abnormal returns during the event window, we cannot confirm abnormal returns for U.S. stocks.

  16. Carbon/graphite composite material study. Appendix C: NASA studies on modification of carbon/graphite fibers and alternative materials

    Science.gov (United States)

    1981-01-01

    The feasibility of modifying resin matrix composites to reduce the potential of electrical shorting from fire released fiber was explored. The effort included modifications to or coatings for graphite fibers, alternative fibers, modifications to matrix materials, and hybrid composites. The objectives included reduction of the conductivity of the graphite fiber, char formation to reduce fiber release, glass formation to prevent fiber release, catalysis to assure fiber consumption in a fire, and replacement of the graphite fibers with nonconductive fibers of similar mechanical potential.

  17. What to provide and how to provide it? : - a study on small companies' demand for audit and alternative services

    OpenAIRE

    Franzén, Liza

    2010-01-01

    The 1st of July 2010 is the statutory audit going to be abolished in Sweden. After the abolition 96 % of the limited companies do not have to conduct an audit.  This research will therefore study the small companies’ demand for audit and alternative services, and how the services shall be provided to best align with the clients’ demands. This study will be conducted with a positivistic perception of knowledge, since the aim is to explain what factors that affect the companies’ demand. With st...

  18. Study on Plastic Coated Overburnt Brick Aggregate as an Alternative Material for Bituminous Road Construction

    Directory of Open Access Journals (Sweden)

    Dipankar Sarkar

    2016-01-01

    Full Text Available There are different places in India where natural stone aggregates are not available for constructional work. Plastic coated OBBA can solve the problem of shortage of stone aggregate to some extent. The engineers are always encouraged to use locally available materials. The present investigation is carried out to evaluate the plastic coated OBBA as an alternative material for bituminous road construction. Shredded waste plastics are mixed with OBBA in different percentages as 0.38, 0.42, 0.46, 0.50, 0.54, and 0.60 of the weight of brick aggregates. Marshall Method of mix design is carried out to find the optimum bitumen content of such bituminous concrete mix prepared by plastic coated OBBA. Bulk density, Marshall Stability, flow, Marshall Quotient, ITS, TSR, stripping, fatigue life, and deformations have been determined accordingly. Marshall Stability value of 0.54 percent of plastic mix is comparatively higher than the other mixes except 0.60 percent of plastic mix. Test results are within the prescribed limit for 0.54 percent of plastic mix. There is a significant reduction in rutting characteristics of the same plastic mix. The fatigue life of the mix is also significantly higher. Thus plastic coated OBBA is found suitable in construction of bituminous concrete road.

  19. Embolization of polycystic kidneys as an alternative to nephrectomy before renal transplantation: a pilot study.

    Science.gov (United States)

    Cornelis, F; Couzi, L; Le Bras, Y; Hubrecht, R; Dodré, E; Geneviève, M; Pérot, V; Wallerand, H; Ferrière, J M; Merville, P; Grenier, N

    2010-10-01

    In autosomal polycystic kidney disease, nephrectomy is required before transplantation if kidney volume is excessive. We evaluated the effectiveness of transcatheter arterial embolization (TAE) to obtain sufficient volume reduction for graft implantation. From March 2007 to December 2009, 25 patients with kidneys descending below the iliac crest had unilateral renal TAE associated with a postembolization syndrome protocol. Volume reduction was evaluated by CT before, 3, and 6 months after embolization. The strategy was considered a success if the temporary contraindication for renal transplantation could be withdrawn within 6 months after TAE. TAE was well tolerated and the objective was reached in 21 patients. The temporary contraindication for transplantation was withdrawn within 3 months after TAE in 9 patients and within 6 months in 12 additional patients. The mean reduction in volume was 42% at 3 months (p = 0.01) and 54% at 6 months (p = 0.001). One patient required a cyst sclerosis to reach the objective. The absence of sufficient volume reduction was due to an excessive basal renal volume, a missed accessory artery and/or renal artery revascularization. Embolization of enlarged polycystic kidneys appears to be an advantageous alternative to nephrectomy before renal transplantation.

  20. Evolving need for alternative triage management in public health emergencies: a Hurricane Katrina case study.

    Science.gov (United States)

    Klein, Kelly R; Pepe, Paul E; Burkle, Frederick M; Nagel, Nanci E; Swienton, Raymond E

    2008-09-01

    In many countries, traditional medical planning for disasters developed largely in response to battlefield and multiple casualty incidents, generally involving corporal injuries. The mass evacuation of a metropolitan population in the aftermath of Hurricane Katrina evolved into life-and-death triage scenarios involving thousands of patients with nontraumatic illnesses and special medical needs. Although unprecedented in the United States, triage management needs for this disaster were similar to other large-scale public health emergencies, both natural and human-generated, that occurred globally in the past half-century. The need for alternative triage-management processes similar to the methodologies of other global mass public health emergencies is illustrated through the experience of disaster medical assistance teams in the first 3 days following Katrina's landfall. The immediate establishment of disaster-specific, consensus-based, public health emergency-related triage protocols-developed with ethical and legal expertise and a renewed focus on multidimensional, multifactorial matrix decision-making processes-is strongly recommended. PMID:18769266

  1. Biased diffusion in tubes of alternating diameter: Numerical study over a wide range of biasing force

    Energy Technology Data Exchange (ETDEWEB)

    Makhnovskii, Yurii A. [Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Leninsky Prospect 29, Moscow 119991 (Russian Federation); Berezhkovskii, Alexander M. [Mathematical and Statistical Computing Laboratory, Division of Computational Bioscience, Center for Information Technology, National Institutes of Health, Bethesda, Maryland 20819 (United States); Antipov, Anatoly E. [Faculty of Fundamental Physics and Chemical Engineering, Moscow State University, GSP-1, 1-51 Leninskie Gory, Moscow 119991 (Russian Federation); Zitserman, Vladimir Yu. [Joint Institute for High Temperatures, Russian Academy of Sciences, Izhorskaya 13, Bldg. 2, Moscow 125412 (Russian Federation)

    2015-11-07

    This paper is devoted to particle transport in a tube formed by alternating wide and narrow sections, in the presence of an external biasing force. The focus is on the effective transport coefficients—mobility and diffusivity, as functions of the biasing force and the geometric parameters of the tube. Dependences of the effective mobility and diffusivity on the tube geometric parameters are known in the limiting cases of no bias and strong bias. The approximations used to obtain these results are inapplicable at intermediate values of the biasing force. To bridge the two limits Brownian dynamics simulations were run to determine the transport coefficients at intermediate values of the force. The simulations were performed for a representative set of tube geometries over a wide range of the biasing force. They revealed that there is a range of the narrow section length, where the force dependence of the mobility has a maximum. In contrast, the diffusivity is a monotonically increasing function of the force. A simple formula is proposed, which reduces to the known dependences of the diffusivity on the tube geometric parameters in both limits of zero and strong bias. At intermediate values of the biasing force, the formula catches the diffusivity dependence on the narrow section length, if the radius of these sections is not too small.

  2. Electronic measurements in an alternating magnetic field (AMF) for studying magnetic nanoparticle hyperthermia

    Science.gov (United States)

    Boekelheide, Z.; Hussein, Z. A.; Hartzell, S.

    Magnetic nanoparticle hyperthermia is a promising cancer treatment in which magnetic nanoparticles are injected into a tumor and then exposed to an alternating magnetic field (AMF). This process releases heat and damages tumor cells, but the exact mechanisms behind the effectiveness of this therapy are still unclear. Accurate sensors are required to monitor the temperature and, potentially, other parameters such as magnetic field or mechanical stress during clinical therapy or lab research. Often, optical rather than electronic temperature sensors are used to avoid eddy current self-heating in conducting parts in the AMF. However, eddy current heating is strongly dependent on the size and geometry of the conducting part, thus micro- and nano-scale electronics are a promising possibility for further exploration into magnetic nanoparticle hyperthermia. This presentation quantitatively discusses the eddy current self-heating of thin wires (thermocouples) and will also present a proof of concept thin film resistive thermometer and magnetic field sensor along with measurements of their eddy current self-heating. The results show that electronic measurements are feasible in an AMF with both thin wires and patterned thin film sensors under certain conditions.

  3. A case study of alternative site response explanatory variables in Parkfield, California

    Science.gov (United States)

    Thompson, E.M.; Baise, L.G.; Kayen, R.E.; Morgan, E.C.; Kaklamanos, J.

    2011-01-01

    The combination of densely-spaced strong-motion stations in Parkfield, California, and spectral analysis of surface waves (SASW) profiles provides an ideal dataset for assessing the accuracy of different site response explanatory variables. We judge accuracy in terms of spatial coverage and correlation with observations. The performance of the alternative models is period-dependent, but generally we observe that: (1) where a profile is available, the square-root-of-impedance method outperforms VS30 (average S-wave velocity to 30 m depth), and (2) where a profile is unavailable, the topographic-slope method outperforms surficial geology. The fundamental site frequency is a valuable site response explanatory variable, though less valuable than VS30. However, given the expense and difficulty of obtaining reliable estimates of VS30 and the relative ease with which the fundamental site frequency can be computed, the fundamental site frequency may prove to be a valuable site response explanatory variable for many applications. ?? 2011 ASCE.

  4. REFLECTIVE TEACHING AS ALTERNATIVE ASSESSMENT IN TEACHER EDUCATION: A CASE STUDY OF PRE-SERVICE TEACHERS

    Directory of Open Access Journals (Sweden)

    GUSTI ASTIKA

    2014-01-01

    Full Text Available Critical reflective teaching has been a goal of English teacher preparation program. Although many English educators have promoted and carried out reflective teaching in their methodology courses, success of such practice has been limited, not sufficiently reflecting what has been desired. Questions have been raised whether reflective teaching within pre-service English teacher education is a realistic aim. One argument for this has been: reflective teaching can only be learned by beginning teachers working in schools with experienced teachers who value critical reflection. This article examines 40 journals of teaching reflection produced by 40 pre-service English teachers after they completed teaching practicum in schools over a period of three months. The journals were analyzed using a theoretical model developed by Smith (2011 which encompasses different purposes with different forms of reflection: personal, interpersonal, contextual, and critical. The analysis shows that the teaching journals contained more reflection on the personal and contextual domains of teaching, indicating that the pre-service teachers were more concerned with the contextual aspects of teaching which influenced their practices in the classroom. It is recommended that a more balanced reflection be created as an alternative form of assessment in English teacher education involving personal as well as social aspects of teaching.

  5. Experimental Study of Entropy Production in Cells under Alternating Electric Field

    Science.gov (United States)

    Ding, Chang-Jiang; Luo, Liao-Fu

    2012-08-01

    We put forward a new method for measuring the entropy production in the living cell. It involves heating the sample by alternating the electric field and recording the outward heat flow. The entropy production in a normal cell MCF10A and a cancerous cell MDA-MB-231 were measured and compared. The results show that the method is effective for the entropy measurement of a living organism. The scaled electro-induced entropy production rate (SEEP) of MDA-MB-231 monotonically increases with the electric field strength at 5-40 V/cm. While that of MCF10A changes non-monotonically and there exists a peak at 5-30 V/cm. The electro-induced entropy production ratio (EEPR) is smaller than 1 in a large range of field strengths, from 5 to 25 V/cm, which reveals that under 5-25 V/cm electric field exposure, the direction of the entropy flow may be changed from normal tissue to cancerous cells. We present a facile and effective strategy for experimentally investigating the thermodynamic properties of the cell and give a deeper insight into the physical difference between normal and cancerous cells under electric field exposure.

  6. Quantitative Imaging Assessment of an Alternative Approach to Surgical Mitral Valve Leaflet Resection: An Acute Porcine Study.

    Science.gov (United States)

    Boronyak, Steven M; Fredi, Joseph L; Young, Michael N; Dumont, Douglas M; Williams, Phillip E; Byram, Brett C; Merryman, W David

    2016-07-01

    This study reports the initial in vivo use of a combined radiofrequency ablation and cryo-anchoring (RFC) catheter as an alternative to surgical mitral valve (MV) leaflet resection. Radiofrequency ablation thermally shrinks enlarged collagenous tissues, providing an alternative to leaflet resection, and cryo-anchoring provides reversible attachment of a catheter to freely mobile MV leaflets. Excised porcine MVs (n = 9) were tested in a left heart flow simulator to establish treatment efficacy criteria. Resected leaflet area was quantified by tracking markers on the leaflet surface, and leaflet length reductions were directly measured on echocardiography. Leaflet area decreased by 38 ± 2.7%, and leaflet length decreased by 9.2 ± 1.8% following RFC catheter treatment. The RFC catheter was then tested acutely in healthy pigs (n = 5) under epicardial echocardiographic guidance, open-chest without cardiopulmonary bypass, using mid-ventricular free wall access. Leaflet length was quantified using echocardiography. Quantitative assessment of MV leaflet length revealed that leaflet resection was successful in 4 of 5 pigs, with a leaflet length reduction of 13.3 ± 4.6%. Histological, mechanical, and gross pathological findings also confirmed that RFC catheter treatment was efficacious. The RFC catheter significantly reduces MV leaflet size in an acute animal model, providing a possible percutaneous alternative to surgical leaflet resection. PMID:26508331

  7. SLIM: an alternative Web interface for MEDLINE/PubMed searches – a preliminary study

    Directory of Open Access Journals (Sweden)

    Ackerman Michael

    2005-12-01

    Full Text Available Abstract Background With the rapid growth of medical information and the pervasiveness of the Internet, online search and retrieval systems have become indispensable tools in medicine. The progress of Web technologies can provide expert searching capabilities to non-expert information seekers. The objective of the project is to create an alternative search interface for MEDLINE/PubMed searches using JavaScript slider bars. SLIM, or Slider Interface for MEDLINE/PubMed searches, was developed with PHP and JavaScript. Interactive slider bars in the search form controlled search parameters such as limits, filters and MeSH terminologies. Connections to PubMed were done using the Entrez Programming Utilities (E-Utilities. Custom scripts were created to mimic the automatic term mapping process of Entrez. Page generation times for both local and remote connections were recorded. Results Alpha testing by developers showed SLIM to be functionally stable. Page generation times to simulate loading times were recorded the first week of alpha and beta testing. Average page generation times for the index page, previews and searches were 2.94 milliseconds, 0.63 seconds and 3.84 seconds, respectively. Eighteen physicians from the US, Australia and the Philippines participated in the beta testing and provided feedback through an online survey. Most users found the search interface user-friendly and easy to use. Information on MeSH terms and the ability to instantly hide and display abstracts were identified as distinctive features. Conclusion SLIM can be an interactive time-saving tool for online medical literature research that improves user control and capability to instantly refine and refocus search strategies. With continued development and by integrating search limits, methodology filters, MeSH terms and levels of evidence, SLIM may be useful in the practice of evidence-based medicine.

  8. Complementary and alternative medicines and childhood eczema: a US population-based study.

    Science.gov (United States)

    Silverberg, Jonathan I; Lee-Wong, Mary; Silverberg, Nanette B

    2014-01-01

    The prevalence of complementary and alternative medicine (CAM) use in US children with eczema is unknown. Furthermore, it is unknown whether CAM use in the United States is associated with higher eczema prevalence. We sought to determine the eczema prevalence in association with CAM usage. We analyzed data from the 2007 National Health Interview Survey that included a nationally representative sample of 9417 children ages 0 to 17 years. Overall, 46.9% (95% confidence interval, 45.6%-48.2%) of children in the United States used 1 or more CAM, of which 0.99% (0.28%-1.71%) used CAM specifically to treat their eczema, including herbal therapy (0.46%), vitamins (0.33%), Ayurveda (0.28%), naturopathy (0.24%), homeopathy (0.20%), and traditional healing (0.12%). Several CAMs used for other purposes were associated with increased eczema prevalence, including herbal therapy (survey logistic regression; adjusted odds ratio [95% confidence interval], 2.07 [1.40-3.06]), vitamins (1.45 [1.21-1.74]), homeopathic therapy (2.94 [1.43-6.00]), movement techniques (3.66 [1.62-8.30]), and diet (2.24 [1.10-4.58]), particularly vegan diet (2.53 [1.17-5.51]). In conclusion, multiple CAMs are commonly used for the treatment of eczema in US children. However, some CAMs may actually be harmful to the skin and be associated with higher eczema prevalence in the United States. PMID:25207686

  9. Hexanoic acid as an alternative diluent in a GANEX process. Feasibility study

    International Nuclear Information System (INIS)

    Used nuclear fuel is radiotoxic for mankind and its environment for a long time. However, if it can be transmuted, the radiotoxicity as well as its heat load are reduced. Before a transmutation the actinides within the used fuel need to be separated from the fission, corrosion and activation products. This separation can be achieved by using the liquid-liquid extraction technique. One extraction process that can be used for such a separation is the Group ActiNide EXtraction (GANEX) process. One GANEX process that can successfully accomplish the separation utilizes the diluent cyclohexanone in combination with the extractant tributylphosphate (TBP) (30 % vol) and a second extractant, CyMe4-BTBP (10 mM). However, there are some issues when using cyclohexanone as diluent. In this work an alternative diluent has therefore been tried in order to determine if it can replace cyclohexanone. The diluent used was hexanoic acid. In a system containing 10-12 mM CyMe4-BTBP and 30 % vol TBP in hexanoic acid with the aqueous phase 4 M HNO3, the distribution ratios for americium and curium are unfortunately low (DAm = 1.1 ± 0.27, D Cm = 1.6 ± 1.81). The concentration of CyMe4-BTBP ligand, the extractant of curium and americium, could unfortunately not be increased, because of limited solubility in hexanoic acid. The distribution ratios for fission, corrosion and activation products were low for most metals; however, cadmium, palladium and molybdenum all unfortunately have distributions ratios above 1. To conclude, low americium and curium extractions indicate that hexanoic acid is not a suitable diluent which could replace cyclohexanone in a GANEX process. (author)

  10. Direct Marketing Alternatives in an Urban Setting: A Case Study of Seattle Youth Garden Works

    Science.gov (United States)

    Taylor, Mykel; Young, Doug; Miles, Carol

    2010-01-01

    The focus of this study is direct marketing of produce from an urban market garden. Rather than discussing broad issues of direct marketing, we use a case study to frame the decisions a market gardener is likely to face in developing both production and marketing plans. The garden featured in this study is located in Seattle, Washington, a city…

  11. Lifeline electric rates and alternative approaches to the problems of low-income ratepayers. Ten case studies of implemented programs

    Energy Technology Data Exchange (ETDEWEB)

    1980-07-01

    Program summaries, issue developments, governmental processes, and impacts are discussed for 10 case studies dealing with lifeline electric rates and alternative approaches to the problems of low-income ratepayers, namely; the Boston Edison rate freeze; the California lifeline; Florida Power and Light conservation rate; the Iowa-Illinois Gas and Electric small-use rate; the Maine demonstration lifeline program; the Massachusetts Electric Company A-65 rate; the Michigan optional senior citizen rate; the Narragansett Electric Company A-65 SSI rate; the Northern States Power Company conservation rate break; and the Potomac Electric Power Company rate freeze. (MCW)

  12. An alternative method to record rising temperatures during dental implant site preparation: a preliminary study using bovine bone

    Directory of Open Access Journals (Sweden)

    Domenica Laurito

    2010-12-01

    Full Text Available Overheating is constantly mentioned as a risk factor for bone necrosis that could compromise the dental implant primary stability. Uncontrolled thermal injury can result in a fibrous tissue, interpositioned at the implant-bone interface, compromising the long-term prognosis. The methods used to record temperature rise include either direct recording by thermocouple instruments or indirect estimating by infrared thermography. This preliminary study was carried out using bovine bone and a different method of temperatures rising estimation is presented. Two different types of drills were tested using fluoroptic thermometer and the effectiveness of this alternative temperature recording method was evaluated.

  13. Alternative Treatments

    Science.gov (United States)

    ... Find your chapter: search by state Home > Alzheimer's Disease > Treatments > Alternative Treatments Overview What Is Dementia? What Is Alzheimer's? Younger/Early Onset Facts and Figures Know the 10 Signs Stages Inside the Brain: ...

  14. Racial and Ethnic Profiles of Complementary and Alternative Medicine Use Among Young Adults in the United States: Findings From the National Longitudinal Study of Adolescent Health.

    Science.gov (United States)

    Upchurch, Dawn M; Wexler Rainisch, Bethany K

    2012-10-01

    This study describes complementary and alternative medicine use among a national sample of young adults, with an emphasis on characterizing racial and ethnic differences, highlighting variation across subgroups of Hispanics. The authors examined young adults ages 18 to 27 years (n = 14 128) from wave III (2001-2002) of the National Longitudinal Study of Adolescent Health. Prevalence estimates and logistic regression results were weighted and adjusted for complex sample design. The study examined recent complementary and alternative medicine use in the past 12 months, recent use for each of 15 specific complementary and alternative medicine modalities, and the 5 most commonly used modalities (herbs, massage, chiropractic, relaxation, and vitamins). Results showed that 29% of young adults aged 18 to 27 years recently used complementary and alternative medicine. Prevalence was highest among Cuban Americans (42%) and lowest among blacks (22%). Young adults used a diversity of complementary and alternative medicine modalities and there were substantial differences in use across racial and ethnic groups.

  15. Oxidising alternative species to chromium VI in zinc-galvanised steel surface treatment. Part 2. An electrochemical study

    Energy Technology Data Exchange (ETDEWEB)

    Almeida, E. [Inst. Nacional de Engenharia e Tecnologia Industrial, Lisbon (Portugal); Fedrizzi, L. [Material Engineering Department, University of Trento, Trento (Italy); Diamantinio, T.C. [Inst. Nacional de Engenharia e Tecnologia Industrial, Lisbon (Portugal)]|[Instituto do Ambiente e Vida, Departamento de Zoologia, Universidade de Coimbra, Coimbra (Portugal)

    1998-06-05

    In the first part of this work, the authors present the main results and conclusions of a morphological and chemical study carried out on zinc conversion layers (ZCLs) obtained with oxidising alternative passivation baths, that includes molybdates, permanganates, vanadates and tungstates. A good chromate-based bath was used as reference. In this second part of the work, the authors present the main results obtained on selected zinc conversion layers (ZCLs), using a.c. electrochemical impedance spectroscopy (EIS). The results obtained were correlated with the morphological and chemical data obtained with the same ZCLs in the first part of this work. Finally, it is concluded that the alternative ZCLs studied, does not seem to be as efficient as that obtained with a chromate-based passivation bath used as reference. It is believed that a better understanding of the mechanisms involved in the ZCL`s formation, can be useful for studying, in the very near future, possible synergetic effects between molybdates and other chemical species. (orig.) 24 refs.

  16. Challenges and potentials in using alternative landscape futures during climate change: A literature review and survey study

    Directory of Open Access Journals (Sweden)

    Amin Rastandeh

    2015-12-01

    Full Text Available This study focuses on the feasibility of applying alternative futures and scenario analysis in landscape planning during climate change to provide a wider perspective and deeper understanding of this approach for better use and more effective application in the future. The study consists of a literature review and an analysis of recent applied projects carried out worldwide. In addition, an electronic survey was conducted from March to September 2014 to examine viewpoints on the use and application of this approach with reference to climate-change impacts. The survey participants were a group of highly experienced researchers from eighteen countries involved in at least one applied project since 2000 relating to this topic. After analysis of more than forty applied projects, the survey results were incorporated into the analysis to create a comprehensive picture regarding the potentials and limitations of alternative futures and scenario analysis in landscape planning with particular attention to climate change. The findings show that this method is one of the most effective decision-making approaches for adopting landscape policies where landscapes change rapidly under the pressure of urbanisation and climate change. Nevertheless, there is a gap between the advances offered by the approach in various dimensions and the complexity of patterns, uncertainties and upheavals in landscapes due to climate-change impacts in the urbanising world. The research indicates that the approach opens up a great opportunity for decision-makers to expand their perspective and adopt appropriate landscape policies before reaching a point of no return from the sustainability point of view. Meanwhile, there are challenges and barriers in the application of alternative futures and scenario analysis for envisioning the landscapes influenced by climate change and urbanisation that should be pushed back. Although informative, this research raises new questions about this

  17. Is there an alternative to increasing the sample size in microarray studies?

    OpenAIRE

    Klebanov, Lev; Yakovlev, Andrei

    2007-01-01

    Our answer to the question posed in the title is negative. This intentionally provocative note discusses the issue of sample size in microarray studies from several angles. We suggest that the current view of microarrays as no more than a screening tool be changed and small sample studies no longer be considered appropriate.

  18. Alternative to Disincentive Rice Producer Prices in Madagascar: Case Study in Alaotra Prefecture and Bongolava Prefecture

    OpenAIRE

    Ralandison, Tsilavo; Shiratake, Yoshiharu

    2008-01-01

    This study identifies the reasons for low producer prices of rice that have not covered its production costs for many years in Madagascar. The following points will be discussed: the farmers’ marketing conditions and the rural rice market structure, including the functions of each intervening trader preceding rice distribution in urban centers. The study also assesses current functions of the agricultural farmer cooperative: an organization expected to enable the establishment of fair trade i...

  19. OBSERVATIONAL STUDY ON SUB ARACHNOID BLOCK IN PRE SUBDUED CHILDREN IS A CHEAP, EFFECTIVE, SAFE ALTERNATIVE TO GENERAL ANAESTHESIA

    Directory of Open Access Journals (Sweden)

    Srilakshmi

    2014-08-01

    Full Text Available Technically, carrying out Spinal Anaesthesia in adults, may not pose much problems, because of patient co-operation, but same is not always so in case of toddlers and children, because of inherent fear of Hospital atmosphere, detachment from parents, immaturity and other. This study aims at performing Spinal Anaesthesia, in children, if they are pre-medicated, and pre-subdued, might pave way for the comfort of both patient and Anesthesiologists. So, pre-medicated, pre-subdued Spinal Technique may be cheaper, safer alternative to General Anaesthesia. In our Observational study, results are satisfactory, with no occurrence of described complications, and study needs to be done in large number of cases.

  20. Clinical outcome of an alternative fotemustine schedule in elderly patients with recurrent glioblastoma: a mono-institutional retrospective study.

    Science.gov (United States)

    Lombardi, Giuseppe; Bellu, Luisa; Pambuku, Ardi; Della Puppa, Alessandro; Fiduccia, Pasquale; Farina, Miriam; D'Avella, Domenico; Zagonel, Vittorina

    2016-07-01

    The optimal treatment of recurrent glioblastoma (GBM) in elderly patients is unclear. Fotemustine (FTM) is a third-generation nitrosourea showing efficacy in gliomas and it has been used with different schedules in adult patients. We performed, for the first time anywhere, a mono-institutional retrospective study to analyze the clinical outcome of an alternative fotemustine schedule in elderly patients with recurrent GBM. Retrospectively, we analyzed all GBM patients 65 years or older previously treated with the combination of radiation therapy and temozolomide (TMZ), receiving an alternative FTM schedule as second-line treatment at our Oncological Center from October 2011 to October 2014 with an ECOG PS ≤ 2. FTM was administrated at 80 mg/m(2) every 2 weeks for five consecutive administrations (induction phase), and then every 4 weeks at 80 mg/m(2) as maintenance. We enrolled 44 patients, 33 males and 11 females; average age was 70 years. ECOG PS was 0-1 in 80 % of the patients. 38 patients relapsed during temozolomide (TMZ) therapy. MGMT methylation status was analyzed in 34 patients and MGMT was methylated in 53 % of the patients. The median progression free survival (PFS) and overall survival (OS) from FTM treatment was 4.1 months (95 % CI 3.1-5.2) and 7 months (95 % CI 5.2-8.4), respectively. Patients with MGMT methylated status and patients who relapsed after completing TMZ therapy had a longer PFS and OS from the beginning of FTM. Thrombocytopenia was the most frequent grade 3-4 haematological toxicity (9 %). The alternative schedule of FTM may be an active and safe treatment for elderly patients with recurrent glioblastoma, especially patients with methylated MGMT and who relapsed after completing temozolomide therapy. PMID:27165580

  1. Studies of transformational leadership: evaluating two alternative models of trust and satisfaction.

    Science.gov (United States)

    Yang, Yi-Feng

    2014-06-01

    This study evaluates the influence of leadership style and employee trust in their leaders on job satisfaction. 341 personnel (164 men, 177 women; M age = 33.5 yr., SD = 5.1) from four large insurance companies in Taiwan completed the transformational leadership behavior inventory, the leadership trust scale and a short version of the Minnesota (Job) Satisfaction Questionnaire. A bootstrapping mediation and structural equation modeling revealed that the effect of transformational leadership on job satisfaction was mediated by leadership trust. This study highlights the importance of leadership trust in leadership-satisfaction relationships, and provides managers with practical ways to enhance job satisfaction.

  2. An alternative approach to treating lateral epicondylitis. A randomized, placebo-controlled, double-blinded study

    NARCIS (Netherlands)

    Nourbakhsh, Mohammad Reza; Fearon, Frank J.

    2008-01-01

    Objective: To investigate the effect of noxious level electrical stimulation on pain, grip strength and functional abilities in subjects with chronic lateral epicondylitis. Design: Randomized, placebo-control, double-blinded study. Setting: Physical Therapy Department, North Georgia College and Stat

  3. Estimating survival rates in ecological studies with small unbalanced sample sizes: an alternative Bayesian point estimator

    Directory of Open Access Journals (Sweden)

    Christian Damgaard

    2011-12-01

    Full Text Available Increasingly, the survival rates in experimental ecology are presented using odds ratios or log response ratios, but the use of ratio metrics has a problem when all the individuals have either died or survived in only one replicate. In the empirical ecological literature, the problem often has been ignored or circumvented by different, more or less ad hoc approaches. Here, it is argued that the best summary statistic for communicating ecological results of frequency data in studies with small unbalanced samples may be the mean of the posterior distribution of the survival rate. The developed approach may be particularly useful when effect size indexes, such as odds ratios, are needed to compare frequency data between treatments, sites or studies.

  4. Assessment of management alternatives for LWR wastes. Volume 1. Main achievements of the joint study

    International Nuclear Information System (INIS)

    This report deals with the main achievements of a joint theoretical study aimed at evaluating a selection of management routes for LWR wastes, relying to a certain extent on national practices in this particular area, on the basis of economical and radiological criteria. All individual intermediate steps entering a management route, from radioactive-wastes production up to their disposal in near-surface sites or in a deep repository, have been identified, described and cost-evaluated throughout the study. The radiological impact assessment comprises estimates of both individual and collective doses resulting from normal discharges of radioactive effluents and from disposal of radioactive waste products in near-surfaces sites. All specific data concerning the description of the different management routes considered as well as the methodology applied to evaluate cost and radiological impact are detailed in the subsequent volumes of the series (Volumes 2 to 8)

  5. The energetic playground : A feasibility study applying energy sources on a Playground: Green Energy alternatives

    OpenAIRE

    Rey-Siso, Daniel

    2016-01-01

    This thesis aims to study the feasibility of using energy generated by the physical activity of children playing in playgrounds. More particular, the goal is to generate clean energy by playing games and showing them the effort about how energy is produced. The ease of turning on lights or using electrical appliance by simply pushing one button causes unawareness of the actual effort and negative impacts of the generation, transmission and distribution behind energy sourcing. The idea of t...

  6. Ichthyotherapy as Alternative Treatment for Patients with Psoriasis: A Pilot Study

    OpenAIRE

    Martin Grassberger; Hoch, W

    2006-01-01

    Ichthyotherapy (therapy with the so-called ‘Doctorfish of Kangal’, Garra rufa) has been shown to be effective in patients with psoriasis in the Kangal hot springs in Turkey. This study evaluates the efficacy and safety of ichthyotherapy in combination with short-term ultraviolet A sunbed radiation in the treatment of psoriasis under controlled conditions. We retrospectively analyzed 67 patients diagnosed with psoriasis who underwent 3 weeks of ichthyotherapy at an outpatient treatment facil...

  7. Probabilistic and Multivariate Modelling in Latin Grammar: the Participle-Auxiliary Alternation as a Case Study

    OpenAIRE

    Brookes, James William Rowe

    2014-01-01

    Recent research has shown that language is sensitive to probabilities and a whole host of multivariate conditioning factors. However, most of the research in this arena centres on the grammar of English, and, as yet, there is no statistical modelling on the grammar of Latin, studies of which have to date been largely philological. The rise in advanced statistical methodologies allows us to capture the underlying structure of the rich datasets which this corpus only language can potentially of...

  8. Magnetic Pattern of Luvisol Sequences From Mexico and Russia: An Alternative Analysis of Soil Studies

    Science.gov (United States)

    Rivas Ortiz, J. F.; Ortega Guerrero, B.; Solleiro Rebolledo, E.; Sedov, S.

    2007-05-01

    Recently, soil has been consolidated like a worthy and complementary source of information to environmental and paleo-climatic reconstruction research. The study of magnetic mineralogy present in soil horizons play an important role to understand a lot of complex process which to allow obtain information about environment condition present during genesis and evolution of soil. The main aim of this study is to compare soils with different parent material, as well as to obtain a magnetic sign from soils profile which could be used to determinate the responsible of pedogenic process of their magnetic behavior of each horizon, and their possible relationship with environmental condition. Study carried out of two complete profiles of buried interglacial Luvisols, one formed in loess in Russia (Alexandrovsky quarry, AQ) and the other in volcaniclastics in Mexico (Barranca Tlalpan, BT). In the AQ, the magnetic susceptibility is enhanced in the paleosol compared to parent material. In the BT sequence, susceptibility enhancement is absent in the soil profile. Increase of fine-grained magnetic components in the soil is attributed to neoformed minerals. However, this process cannot compensate for the loss of lithogenic magnetic minerals in any of the genetic horizons, and the resulting trend is susceptibility depletion in the whole soil profile. The pedogenic environment of eluvial horizons in both Luvisols is destructive to all magnetic components, both primary and secondary. Higher concentrations of antiferromagnetic components (hematite and goethite) found in E horizons are related to redoximorphic processes.

  9. A pilot study of rivastigmine in the treatment of delirium after stroke: A safe alternative

    Directory of Open Access Journals (Sweden)

    Jansen Ben PW

    2008-09-01

    Full Text Available Abstract Background Delirium is a common disorder in the early phase of stroke. Given the presumed cholinergic deficiency in delirium, we tested treatment with the acetylcholinesterase inhibitor rivastigmine. Methods This pilot study was performed within an epidemiological study. In 527 consecutive stroke patients presence of delirium was assessed during the first week with the confusion assessment method. Severity was scored with the delirium rating scale (DRS. Sixty-two patients developed a delirium in the acute phase of stroke. Only patients with a severe and persistent delirium (defined as a DRS of 12 or more for more than 24 hours were enrolled in the present study. In total 26 fulfilled these criteria of whom 17 were treated with orally administered rivastigmine with a total dose between 3 and 12 mg a day. Eight patients could not be treated because of dysphagia and one because of early discharge. Results No major side effects were recorded. In 16 patients there was a considerable decrease in severity of delirium. The mean DRS declined from 14.8 on day one to 8.5 after therapy and 5.6 after tapering. The mean duration of delirium was 6.7 days (range; 2–17. Conclusion Rivastigmine is safe in stroke patients with delirium even after rapid titration. In the majority of patients the delirium improved after treatment. A randomized controlled trial is needed to establish the usefulness of rivastigmine in delirium after stroke. Trial registration Nederlands Trial Register NTR1395

  10. Investigation of potential alternate study areas in the Paradox Basin region, Utah

    International Nuclear Information System (INIS)

    The Paradox Basin was re-evaluated to determine if any parts of the Basin that had not been identified in previous studies might be suitable for a more detailed evaluation as a nuclear waste repository site. The factors used in this re-evaluation were depth to salt and dedicated lands, because these factors directly address the engineering and environmental feasibility of a repository. Six areas (Happy Canyon, Green River, Dolores River, Expectation Mountain, Dark Canyon, and Kane Springs Canyon) were identified on this basis as potentially suitable areas for further study. These areas were assessed in more detail to review the feasibility of siting a repository. None of the six areas was recommended for further study as a repository site because the size of the areas, thickness of the salt beds, topography, and engineering factors resulting from the loading of nearby mesas generally did not allow the construction of a feasible repository. The content of this report was effective as of May 1983. 41 references, 17 figures

  11. EXPERIMENTAL STUDY OF PALM OIL MILL EFFLUENT AND OIL PALM FROND WASTE MIXTURE AS AN ALTERNATIVE BIOMASS FUEL

    Directory of Open Access Journals (Sweden)

    S. HASSAN, L. S. KEE

    2013-12-01

    Full Text Available Palm oil mill effluent (POME sludge generated from palm oil mill industry and oil palm frond (OPF from oil palm plantation are considered biomass wastes that can be fully utilized as a renewable energy sources. In this study, an attempt has been made to convert these residues into solid biomass fuel. The study was conducted by developing experimental testing on the POME and OPF mixture. The performance of each sample with different weight percentage was investigated using standard tests. The biomass mixture was converted into compressed form of briquette through a simple process. The properties of the briquettes were observed and compared at different weight percentage following standard testing methods included ultimate and proximate analyses, burning characteristics, dimensional stability and crack analysis. Experimental results showed that POME sludge and OPF mixture is feasible as an alternative biomass fuel, with briquette of 90:10 POME sludge to OPF ratio has a good combination of properties as an overall.

  12. Cosmic alternatives?

    Science.gov (United States)

    Gregory, Ruth

    2009-04-01

    "Cosmologists are often in error but never in doubt." This pithy characterization by the Soviet physicist Lev Landau sums up the raison d'être of Facts and Speculations in Cosmology. Authors Jayant Narlikar and Geoffrey Burbidge are proponents of a "steady state" theory of cosmology, and they argue that the cosmological community has become fixated on a "Big Bang" dogma, suppressing alternative viewpoints. This book very much does what it says on the tin: it sets out what is known in cosmology, and puts forward the authors' point of view on an alternative to the Big Bang.

  13. Outlook for alternative transportation fuels

    Energy Technology Data Exchange (ETDEWEB)

    Gushee, D.E. [Univ. of Illinois, Chicago, IL (United States)

    1996-12-31

    This presentation provides a brief review of regulatory issues and Federal programs regarding alternative fuel use in automobiles. A number of U.S. DOE initiatives and studies aimed at increasing alternative fuels are outlined, and tax incentives in effect at the state and Federal levels are discussed. Data on alternative fuel consumption and alternative fuel vehicle use are also presented. Despite mandates, tax incentives, and programs, it is concluded alternative fuels will have minimal market penetration. 7 refs., 5 tabs.

  14. Primary healthcare provider knowledge, beliefs and clinic-based practices regarding alternative tobacco products and marijuana: a qualitative study.

    Science.gov (United States)

    Bascombe, Ta Misha S; Scott, Kimberly N; Ballard, Denise; Smith, Samantha A; Thompson, Winifred; Berg, Carla J

    2016-06-01

    Use prevalence of alternative tobacco products and marijuana has increased dramatically. Unfortunately, clinical guidelines have focused on traditional cigarettes with limited attention regarding these emerging public health issues. Thus, it is critical to understand how healthcare professionals view this issue and are responding to it. This qualitative study explored knowledge, beliefs and clinic-based practices regarding traditional and alternative tobacco products (cigar-like products, smokeless tobacco, hookah, e-cigarettes) and marijuana among rural and urban Georgia primary healthcare providers. The sample comprised 20 healthcare providers in primary care settings located in the Atlanta Metropolitan area and rural southern Georgia who participated in semi-structured interviews. Results indicated a lack of knowledge about these products, with some believing that some products were less harmful than traditional cigarettes or that they may be effective in promoting cessation or harm reduction. Few reported explicitly assessing use of these various products in clinic. In addition, healthcare providers reported a need for empirical evidence to inform their clinical practice. Healthcare providers must systematically assess use of the range of tobacco products and marijuana. Evidence-based recommendations or information sources are needed to inform clinical practice and help providers navigate conversations with patients using or inquiring about these products. PMID:26802106

  15. Ichthyotherapy as Alternative Treatment for Patients with Psoriasis: A Pilot Study

    Directory of Open Access Journals (Sweden)

    Martin Grassberger

    2006-01-01

    Full Text Available Ichthyotherapy (therapy with the so-called ‘Doctorfish of Kangal’, Garra rufa has been shown to be effective in patients with psoriasis in the Kangal hot springs in Turkey. This study evaluates the efficacy and safety of ichthyotherapy in combination with short-term ultraviolet A sunbed radiation in the treatment of psoriasis under controlled conditions. We retrospectively analyzed 67 patients diagnosed with psoriasis who underwent 3 weeks of ichthyotherapy at an outpatient treatment facility in Lower Austria between 2002 and 2004. Main outcome measures are as follows: overall relative reduction in Psoriasis Area Severity Index (PASI score; proportion of patients with an improvement in their PASI score of ≥75% (PASI-75 and ≥50% (PASI-50; patient-reported outcomes assessed with a custom questionnaire; and patient follow-up with a questionnaire sent out in March 2005. Safety was evaluated by reviewing adverse events and vital signs. Overall there was a 71.7% reduction in PASI score compared to baseline (P < 0.0001. Of the 67 patients studied, 31 (46.3% achieved PASI-75 and 61 patients (91% achieved at least PASI-50. Patients reported substantial satisfaction with the treatment. The reported mean remission period was 8.58 months [95% confidence interval (CI 6.05–11.11]. A total of 87.5% of patients reported a more favorable outcome with ichthyotherapy, when asked to compare ichthyotherapy to other previously tried therapies. Sixty-five percent stated that after the relapse their symptoms were less severe than before treatment. There were no significant adverse events. The benefit demonstrated in this study along with the favorable safety profile suggests that ichthyotherapy could provide a viable treatment option for patients with psoriasis.

  16. The study of wear behaviors on abducted hip joint prostheses by an alternate finite element approach.

    Science.gov (United States)

    Lin, Yi-Tsung; Wu, James Shih-Shyn; Chen, Jian-Horng

    2016-07-01

    An acetabular cup with larger abduction angles is able to affect the normal function of the cup seriously that may cause early failure of the total hip replacement (THR). Complexity of the finite element (FE) simulation in the wear analysis of the THR is usually concerned with the contact status, the computational effort, and the possible divergence of results, which become more difficult on THRs with larger cup abduction angles. In the study, we propose a FE approach with contact transformation that offers less computational effort. Related procedures, such as Lagrangian Multiplier, partitioned matrix inversion, detection of contact forces, continuity of contact surface, nodal area estimation, etc. are explained in this report. Through the transformed methodology, the computer round-off error is tremendously reduced and the embedded repetitive procedure can be processed precisely and quickly. Here, wear behaviors of THR with various abduction angles are investigated. The most commonly used combination, i.e., metal-on-polyethylene, is adopted in the current study where a cobalt-chromium femoral head is paired with an Ultra High Molecular Weight Polyethylene (UHMWPE) cup. In all illustrations, wear coefficients are estimated by self-averaging strategy with available experimental datum reported elsewhere. The results reveal that the THR with larger abduction angles may produce deeper depth of wear but the volume of wear presents an opposite tendency; these results are comparable with clinical and experimental reports. The current approach can be widely applied easily to fields such as the study of the wear behaviors on ante-version, impingement, and time-dependent behaviors of prostheses etc. PMID:27265055

  17. A Comparative Study of Alternate Iron and Folic Acid Supplementation Regimes in Childhood Anaemia

    Directory of Open Access Journals (Sweden)

    Bhuwan R Sharma

    2014-02-01

    Full Text Available Introduction: The prevalence of anaemia among children less than five years of age in India is around 70%. Anaemia in young children puts them at a higher risk of experiencing health problems such as stunted growth, mental retardation, and increased susceptibility to infectious diseases. The present study was undertaken to evaluate the effectiveness of IFA supplementation (daily vs. biweekly vs. weekly regime on haemoglobin levels of young children. Materials and Methods: A total 740 children in age group of six months to five years were included in this community based interventional study using Systemic random sampling. The children having mild to moderate anaemia were then divided into three groups A, B and C by simple random sampling and were given Iron and Folic acid supplementation daily, biweekly and weekly respectively. Follow up data was collected after 3 months and analysed using appropriate tests. Results: Prevalence of Anaemia was 91.1% among study participants. Comparison after 3 months showed significant change in haemoglobin levels in all three groups with mean improvement of 1.31 gm%, 0.89 gm% and 0.85 gm% in group A, B and C respectively. However, no significant difference was noted among the groups in pre as well as post intervention phase. Conclusion: Weekly regime is as effective as daily or biweekly regime in improving haemoglobin levels in children. Moreover, it has better compliance, lesser side effects and cost of therapy. So, the same should be recommended for prophylaxis as well as treatment of mild to moderate anaemia cases. [Natl J Med Res 2014; 4(1.000: 33-36

  18. Simulation Study Using an Injection Phase-locked Magnetron as an Alternative Source for SRF Accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Haipeng [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Plawski, Tomasz E. [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Rimmer, Robert A. [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States)

    2015-09-01

    As a drop-in replacement for the CEBAF CW klystron system, a 1497 MHz, CW-type high-efficiency magnetron using injection phase lock and amplitude variation is attractive. Amplitude control using magnetic field trimming and anode voltage modulation has been studied using analytical models and MATLAB/Simulink simulations. Since the 1497 MHz magnetron has not been built yet, previously measured characteristics of a 2.45GHz cooker magnetron are used as reference. The results of linear responses to the amplitude and phase control of a superconducting RF (SRF) cavity, and the expected overall benefit for the current CEBAF and future MEIC RF systems are presented in this paper.

  19. An alternative time marker for the study of the uniform and uniformly accelerated movements

    Directory of Open Access Journals (Sweden)

    Osmar Henrique Moura da Silva

    2003-01-01

    Full Text Available This work presents a type of time marker set up with materials of low cost for the study of uniform movements as well as those accelerated by gravitacional force. A mechanism used to measure its frequency is coupled to it in order to find the approximate value of the acceleration of the local gravity. The experiment, that is adapted to be used during a kinematics class, can also be presented by the students at a science fair, for being a stimulating factor as it involves the students’ participation in its construction.

  20. Simulation Study Using an Injection Phase-locked Magnetron as an Alternative Source for SRF Accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Haipeng [Jefferson Lab, Newport News, VA; Plawski, Tomasz E. [Jefferson Lab, Newport News, VA; Rimmer, Robert A. [Jefferson Lab, Newport News, VA

    2015-09-01

    As a drop-in replacement for the CEBAF CW klystron system, a 1497 MHz, CW type high efficiency magnetron using injection phase lock and amplitude variation is attractive. Amplitude control using magnetic field trimming and anode voltage modulation has been studied using analytical models and MATLAB/Simulink simulations. Since the 1497 MHz magnetron has not been built yet, previously measured characteristics of a 2.45GHz cooker magnetron are used as reference. The results of linear responses to the amplitude and phase control of a superconducting RF (SRF) cavity, and the expected overall benefit for the current CEBAF and future MEIC RF systems are presented in this paper.

  1. Technical Approach and Results from the Fuels Pathway on an Alternative Selection Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Bob Youngblood; Curtis Smith

    2013-09-01

    The report presents a detailed plan for conducting case studies to characterize probabilistic safety margins associated with different fuel cladding types in a way that supports a valid comparison of different fuels' performance. Recent work performed in other programs is described briefly and used to illustrate the challenges posed by characterization of margin in a probabilistic way. It is additionally pointed out that consistency of evaluation of performance across different cladding types is not easy to assure; a process for achieving the needed consistency is described.

  2. Study of Solar Cooling Alternatives for Residential Houses in Bahir dar city :

    OpenAIRE

    Mengistu, Meron Mulatu

    2011-01-01

    The energy consumption rate of non-OECD countries rises about 2.3 percent per year as compared to the energy consumption rate of OECD countries which is 0.6 percent. If developing countries use energy efficient technology and integrate renewable energy systems in the new building their carbon dioxide emission rate reduces by 25 to 44 percent.  However, even now, renewable energy integrated buildings are hardly considered while constructing them.   This thesis work focuses on the study of sola...

  3. Experimental study on spray characteristics of alternate jet fuels using Phase Doppler Anemometry

    Science.gov (United States)

    Kannaiyan, Kumaran; Sadr, Reza

    2013-11-01

    Gas-to-Liquid (GTL) fuels have gained global attention due to their cleaner combustion characteristics. The chemical and physical properties of GTL jet fuels are different from conventional jet fuels owing to the difference in their production methodology. It is important to study the spray characteristics of GTL jet fuels as the change of physical properties can affect atomization, mixing, evaporation and combustion process, ultimately affecting emission process. In this work, spray characteristics of two GTL synthetic jet fuels are studied using a pressure-swirl nozzle at different injection pressures and atmospheric ambient condition. Phase Doppler Anemometry (PDA) measurements of droplet size and velocity are compared with those of regular Jet A-1 fuel at several axial and radial locations downstream of the nozzle exit. Experimental results show that although the GTL fuels have different physical properties such as viscosity, density, and surface tension, among each other the resultant change in the spray characteristics is insignificant. Furthermore, the presented results show that GTL fuel spray characteristics exhibit close similarity to those of Jet A-1 fuel. Funded by Qatar Science and Technology Park.

  4. Alternations of functional connectivity in amblyopia patients: a resting-state fMRI study

    Science.gov (United States)

    Wang, Jieqiong; Hu, Ling; Li, Wenjing; Xian, Junfang; Ai, Likun; He, Huiguang

    2014-03-01

    Amblyopia is a common yet hard-to-cure disease in children and results in poor or blurred vision. Some efforts such as voxel-based analysis, cortical thickness analysis have been tried to reveal the pathogenesis of amblyopia. However, few studies focused on alterations of the functional connectivity (FC) in amblyopia. In this study, we analyzed the abnormalities of amblyopia patients by both the seed-based FC with the left/right primary visual cortex and the network constructed throughout the whole brain. Experiments showed the following results: (1)As for the seed-based FC analysis, FC between superior occipital gyrus and the primary visual cortex was found to significantly decrease in both sides. The abnormalities were also found in lingual gyrus. The results may reflect functional deficits both in dorsal stream and ventral stream. (2)Two increased functional connectivities and 64 decreased functional connectivities were found in the whole brain network analysis. The decreased functional connectivities most concentrate in the temporal cortex. The results suggest that amblyopia may be caused by the deficits in the visual information transmission.

  5. Study of Oxidizing Agents for Tritium Removal in ITER -Compatible Conditions: Alternatives to Oxygen and Ozone

    Energy Technology Data Exchange (ETDEWEB)

    Tabares, F. L.; Tafalla, D.; Ferreira, J. A.; Gomez-Aleixandre, C.; Maria Albella, J.; Soria, J.; Rodriguez-Ramos, I.

    2007-07-20

    In the present report, the studies of tritiated carbon-film removal by oxidizing agents other than Oxygen and Ozone in ITER are described. Exposure of laboratory produced a-C:H/D films and tokamak flakes (Asdex Upgrade and Textor) to nitric oxide, water and hydrogen peroxide has been carried out. Temperatures of exposure up to 350 degree centigree were used, and thermal desorption of the samples at temperatures up to 750 degree centigree was performed for sample characterization prior to and after the treatment. Elastic Recoil Detection Analysis (ERDA), Infrared Spectroscopy, XPS and Nano indentation hardness analysis were applied to the characterization of the physical and chemical changes of the samples. This work was done under the EFDA Task 04-1175. (Author) 8 refs.

  6. Study of Oxidizing Agents for Tritium Removal in ITER -Compatible Conditions: Alternatives to Oxygen and Ozone

    International Nuclear Information System (INIS)

    In the present report, the studies of tritiated carbon-film removal by oxidizing agents other than Oxygen and Ozone in ITER are described. Exposure of laboratory produced a-C:H/D films and tokamak flakes (Asdex Upgrade and Textor) to nitric oxide, water and hydrogen peroxide has been carried out. Temperatures of exposure up to 350 degree centigree were used, and thermal desorption of the samples at temperatures up to 750 degree centigree was performed for sample characterization prior to and after the treatment. Elastic Recoil Detection Analysis (ERDA), Infrared Spectroscopy, XPS and Nano indentation hardness analysis were applied to the characterization of the physical and chemical changes of the samples. This work was done under the EFDA Task 04-1175. (Author) 8 refs

  7. Growing Alternatives

    DEFF Research Database (Denmark)

    Bagger-Petersen, Mai Corlin

    2014-01-01

    From 2014, Anhui Province will pilot a reform of the residential land market in China, thus integrating rural Anhui in the national housing market. In contrast, artist and activist Ou Ning has proposed the Bishan time money currency, intending to establish an alternative economic circuit in Bishan...

  8. Battlefield Utility of Antipersonnel Landmines and Proposed Alternatives (Analysis in Support of the NATO SAS-023 APM Study)

    Energy Technology Data Exchange (ETDEWEB)

    Crandley, J F; Greenwalt, R J; Magnoli, D E; Randazzo, A S

    2002-02-05

    This study consists of work done in support of the U.S. delegation to the NATO SAS-023 Antipersonnel Landmine Study Group, supplemented by additional work done for the U.S. Office of the Secretary of Defense Antipersonnel Landmine Alternative Concept Exploration Program (Track III). It explores the battlefield utility of current antipersonnel landmines (APL) in both pure and mixed APL/antitank minefields and evaluates the value of military suggested non-materiel alternatives. The historical record is full of examples where the presence (or absence) of antipersonnel landmines made a critical difference in battle. The current generation of military thinkers and writers lack any significant combat experience employing either mixed or antipersonnel minefields, which leaves a critical gap in available expert advice for policy and decision-makers. Because of this lack of experienced-based professional military knowledge, Lawrence Livermore National Laboratory analyzed the employment of antipersonnel landmines in tactical mixed minefields and in protective antipersonnel minefields. The scientific method was employed where hypotheses were generated from the tactics and doctrine of the antipersonnel landmine era and tested in a simulation laboratory. A high-resolution, U.S. Joint Forces Command combat simulation model (the Joint Conflict and Tactical Simulation--JCATS) was used as the laboratory instrument. A realistic European scenario was obtained from a multi-national USAREUR exercise and was approved by the SAS-023 panel members. Additional scenarios were provided by U.S. CINC conferences and were based on Southwest Asia and Northeast Asia. Weapons data was obtained from the U.S. family of Joint Munitions Effectiveness Manuals. The U.S. Army Materiel Systems Analysis Agency conducted a limited verification and validation assessment of JCATS for purposes of this study.

  9. Hanford waste vitrification plant hydrogen generation study: Preliminary evaluation of alternatives to formic acid

    Energy Technology Data Exchange (ETDEWEB)

    King, R.B.; Bhattacharyya, N.K.; Kumar, V.

    1996-02-01

    Oxalic, glyoxylic, glycolic, malonic, pyruvic, lactic, levulinic, and citric acids as well as glycine have been evaluated as possible substitutes for formic acid in the preparation of feed for the Hanford waste vitrification plant using a non-radioactive feed stimulant UGA-12M1 containing substantial amounts of aluminum and iron oxides as well as nitrate and nitrite at 90C in the presence of hydrated rhodium trichloride. Unlike formic acid none of these carboxylic acids liberate hydrogen under these conditions and only malonic and citric acids form ammonia. Glyoxylic, glycolic, malonic, pyruvic, lactic, levulinic, and citric acids all appear to have significant reducing properties under the reaction conditions of interest as indicated by the observation of appreciable amounts of N{sub 2}O as a reduction product of,nitrite or, less likely, nitrate at 90C. Glyoxylic, pyruvic, and malonic acids all appear to be unstable towards decarboxylation at 90C in the presence of Al(OH){sub 3}. Among the carboxylic acids investigated in this study the {alpha}-hydroxycarboxylic acids glycolic and lactic acids appear to be the most interesting potential substitutes for formic acid in the feed preparation for the vitrification plant because of their failure to produce hydrogen or ammonia or to undergo decarboxylation under the reaction conditions although they exhibit some reducing properties in feed stimulant experiments.

  10. Study on an alternating current electrothermal micropump for microneedle-based fluid delivery systems

    Science.gov (United States)

    Zhang, Rumi; Jullien, Graham A.; Dalton, Colin

    2013-07-01

    In this paper, we report on a modeling study of an AC electrothermal (ACET) micropump with high operating pressures as well as fast flow rates. One specific application area is for fluid delivery using microneedle arrays which require higher pressures and faster flow rates than have been previously reported with ACET devices. ACET is very suitable for accurate actuation and control of fluid flow, since the technique has been shown to be very effective in high conductivity fluids and has the ability to create a pulsation free flow. However, AC electrokinetic pumps usually can only generate low operating pressures of 1 to 100 Pa, where flow reversal is likely to occur with an external load. In order to realize a high performance ACET micropump for continuous fluid delivery, applying relatively high AC operating voltages (20 to 36 Vrms) to silicon substrate ACET actuators and using long serpentine channel allows the boosting of operating pressure as well as increasing the flow rates. Fast pumping flow rates (102-103 nl/s) and high operating pressures (1-12 kPa) can be achieved by applying both methods, making them of significant importance for continuous fluid delivery applications using microneedle arrays and other such biomedical devices.

  11. Study of energy recovery and power generation from alternative energy source

    Directory of Open Access Journals (Sweden)

    Abdulhakim Amer A. Agll

    2014-11-01

    Full Text Available The energy requirement pattern of world is growing up and developing technology. The available sources, while exhausting and not friendly to the environment, are highly used. Looking at partial supply and different options of environment problems associated with usage, renewable energy sources are getting attention. MSW (Municipal solid waste composition data had been collected from 1997 to 2009, in Benghazi Libya, to evaluate the waste enthalpy. An incinerator with capacity of 47,250 kg/h was confirmed to burn all the quantity of waste generated by the city through the next 15 years. Initial study was performed to investigate energy flow and resource availability to insure sustainable MSW required by the incinerator to work at its maximum capacity during the designated period. The primary purpose of the paper is to discuss the design of Rankin steam cycle for the generation of both power (PG and combined heat power (CHP. In the power generation case, the system was found to be able to generate electrical power of 13.1 MW. Including the combined heat power case, the results showed that the system was able to produce 6.8 million m3/year of desalinated water and generate 11.33 MW of electricity. In conclusion, the CHP designed system has the greatest potential to maximize energy saving, due to the optimal combination of heat production and electricity generation.

  12. Study of a new alternative antioxidant in soybean plants subjected to abiotic stress

    International Nuclear Information System (INIS)

    We have recently, demonstrated that the induction of heme oxygenase-1 (HO-1) plays a protective role for soybean plants against oxidative stress produced by cadmium and UV-B radiation. At this moment we propose to investigate if the enzyme has the same capacity against another type of abiotic stress, such as drought, for to demonstrate that heme oxygenase acts as an enzyme of plant antioxidant defense system under several different stress situations, as occur in mammalian tissues. To carry out this objective we propose to study, in leaf, root and nodule of soybean plants, the oxidative stress generation; the behavior of classical antioxidant system; the behavior of HO-1 activity and protein and gene expression; the effect of its reaction products and inhibitors on the oxidative stress parameters; the signaling mechanism that produce HO-1 induction and the immunohistochemistry localization of the enzyme in the different plant tissues. The results obtained let us undoubtedly demonstrate the involvement of HO-1 in the antioxidant defense system in plants. This finding will allow the increase in the knowledge of the defense mechanisms in interesting economic plants for our country, such as soybean, and against drought, an abiotic stress considered one of the most important factors limiting plant performance and yield worldwide. (authors)

  13. Mobile radio alternative systems study satellite/terrestrial (hybrid) systems concepts

    Science.gov (United States)

    Kiesling, J. D.; Anderson, R. E.

    1983-01-01

    The use of satellites for mobile radio service in non-urban areas of the United States in the years from 1985 to 2000 was investigated. Several satellite concepts are considered: a system with single-beam coverage of the fifty United States and Puerto Rico, and multi-beam satellites with greater capacity. All of the needed functions and services identified in the market study are provided by the satellite systems, including nationwide radio access to vehicles without knowledge of vehicle location wideband data transmission from remote sites, two way exchange of short data and control messages between vehicles and dispatch or control centers, and automatic vehicle location (surveillance). The costs of providing the services are within acceptable limits, and the desired returns to the system investors are attractive. The criteria by which the Federal Communication judges the competing demands for public radio spectrum are reviewed with comments on how the criteria might apply to the consideration of land mobile satellites. Institutional arrangements for operating a mobile satellite system are based on the present institutional arrangements in which the services are offered to the end users through wireline and radio common carriers, with direct access by large private and government users.

  14. Management functions, issues, and configuration alternatives: TO support a transportation management configuration study: [Final report

    International Nuclear Information System (INIS)

    The Office of Civilian Radioactive Waste Management (OCRWM) of the Department of Energy (DOE) is responsible for the safe transporation and disposal of spent nuclear fuel from utility-owned nuclear power generation reactors and high-level radioactive waste from both defense and civilian generators to long-term storage repositories. Given the volume, duration, and sensitivity of the operation, DOE is seeking not only the safest and best transportation system but also the most effective and resource-efficient management concept. Within the general guidelines of the Nuclear Waste Policy Act (NWPA) of 1982 calling for the fullest possible use of private industry contracts, this study examines the technical and administrative functions as well as the key issues to be addressed in the formation of a management structure. In order to stand alone as a comprehensive treatment of the total requirement, the material contained in many seperate and sometimes divergent DOE/OCRWM documents was evaluated and is compiled here. An attempt was made to succinctly define the nature of the problem, the objectives and scope of both the operating and management systems, and then to dissect the functions required in order to meet the objectives and operating functions are listed and described

  15. Altitude Effects on Thermal Ice Protection System Performance; a Study of an Alternative Approach

    Science.gov (United States)

    Addy, Harold E., Jr.; Orchard, David; Wright, William B.; Oleskiw, Myron

    2016-01-01

    Research has been conducted to better understand the phenomena involved during operation of an aircraft's thermal ice protection system under running wet icing conditions. In such situations, supercooled water striking a thermally ice-protected surface does not fully evaporate but runs aft to a location where it freezes. The effects of altitude, in terms of air pressure and density, on the processes involved were of particular interest. Initial study results showed that the altitude effects on heat energy transfer were accurately modeled using existing methods, but water mass transport was not. Based upon those results, a new method to account for altitude effects on thermal ice protection system operation was proposed. The method employs a two-step process where heat energy and mass transport are sequentially matched, linked by matched surface temperatures. While not providing exact matching of heat and mass transport to reference conditions, the method produces a better simulation than other methods. Moreover, it does not rely on the application of empirical correction factors, but instead relies on the straightforward application of the primary physics involved. This report describes the method, shows results of testing the method, and discusses its limitations.

  16. Mobile radio alternative systems study satellite/terrestrial (hybrid) systems concepts

    Science.gov (United States)

    Kiesling, J. D.; Anderson, R. E.

    1983-06-01

    The use of satellites for mobile radio service in non-urban areas of the United States in the years from 1985 to 2000 was investigated. Several satellite concepts are considered: a system with single-beam coverage of the fifty United States and Puerto Rico, and multi-beam satellites with greater capacity. All of the needed functions and services identified in the market study are provided by the satellite systems, including nationwide radio access to vehicles without knowledge of vehicle location wideband data transmission from remote sites, two way exchange of short data and control messages between vehicles and dispatch or control centers, and automatic vehicle location (surveillance). The costs of providing the services are within acceptable limits, and the desired returns to the system investors are attractive. The criteria by which the Federal Communication judges the competing demands for public radio spectrum are reviewed with comments on how the criteria might apply to the consideration of land mobile satellites. Institutional arrangements for operating a mobile satellite system are based on the present institutional arrangements in which the services are offered to the end users through wireline and radio common carriers, with direct access by large private and government users.

  17. Study on Color and Antioxidant Properties of Rambutan Seed Fat as Cocoa Butter Alternative

    Directory of Open Access Journals (Sweden)

    Luma Khairy. H

    2015-03-01

    Full Text Available In this paper, the color (whiteness, L*, a*, b* and antioxidant properties (radical scavenging activity, total phenolic compound of rambutan seed fat (RSF and its mixture with cocoa butter (CB were investigated. Different proportions were applied in preparing the samples between (RSF and (CB. The results showed that significant differences among samples in the whiteness, (L* and (a* value, whereas (b* value had no significant differences. With regard antioxidant activity the results showed that total phenolic compound (TPC of cocoa butter was (47.37±0.02 mg GA/100 g fat, while the other mixtures between (RSF and (CB showed (40.49±0.01-11.12±0.02 mg GA/100 g fat. Radical scavenging activity (DPPH of cocoa butter valued (67.32±0.44 µmol trolox/100 g fat, similar to the mixture M1 (60.16±0.23. Based on the results the study recommended that mixture ratio up to 40% rambutan seed fat (RSF can benefit as a cocoa butter replacer whereas a higher ratio completely change original cocoa butter characteristics. Thus, there is the possibility of using the (RSF as replacer of (CB and could utilize by chocolate products.

  18. Dentine microhardness changes following conventional and alternate irrigation regimens: An in vitro study

    Directory of Open Access Journals (Sweden)

    Anusree Das

    2014-01-01

    Full Text Available Aim: To compare the changes in microhardness of root dentin caused by two novel irrigation regimens with conventional irrigation. Materials and Methods: Forty extracted human permanent incisor teeth were selected. Decoronated roots were separated longitudinally to get 80 specimens that were embedded in autopolymerizing acrylic resin and grounded flat with silicon carbide abrasive papers. Of these, 60 root segments without any cracks or defects were selected and divided into four groups according to the irrigation regimen used (n = 15. Group I: 5% sodium hypochlorite (NaOCl + 17% ethylenediaminetetraacetic acid (EDTA + 0.2% chlorhexidine digluconate (CHX (conventional. Group II: 6% Morinda Citrifolia Juice + 17% EDTA (MCJ. Group III: 5% NaOCl + Q Mix 2 in 1 (QMix. Group IV: Distilled water (control. Irrigation regimens were performed for 5 minutes. Dentin microhardness was measured with a Vickers indenter under a 200-g load and a 20-s dwell time at the midroot level of root dentin. The data were analyzed using Kruskal Wallis test and Dunn′s multiple comparison tests. Results: A significant difference was seen in the median values of the four groups. The control group showed the least reduction in microhardness when comparison with the other groups. Except for Group III (Q Mix, the other groups that were tested (MCJ and conventional regimens showed statistically significant difference from the control group. Conclusion: Within the limitation of this study, it was concluded that NaOCl + Q Mix were least detrimental to root dentin microhardness when compared with MCJ and conventional irrigation regimens.

  19. A pilot study evaluating alternative approaches of academic detailing in rural family practice clinics

    Directory of Open Access Journals (Sweden)

    Hartung Daniel M

    2012-12-01

    Full Text Available Abstract Background Academic detailing is an interactive, convenient, and user-friendly approach to delivering non-commercial education to healthcare clinicians. While evidence suggests academic detailing is associated with improvements in prescribing behavior, uncertainty exists about generalizability and scalability in diverse settings. Our study evaluates different models of delivering academic detailing in a rural family medicine setting. Methods We conducted a pilot project to assess the feasibility, effectiveness, and satisfaction with academic detailing delivered face-to-face as compared to a modified approach using distance-learning technology. The recipients were four family medicine clinics within the Oregon Rural Practice-based Research Network (ORPRN. Two clinics were allocated to receive face-to-face detailing and two received outreach through video conferencing or asynchronous web-based outreach. Surveys at midpoint and completion were used to assess effectiveness and satisfaction. Results Each clinic received four outreach visits over an eight month period. Topics included treatment-resistant depression, management of atypical antipsychotics, drugs for insomnia, and benzodiazepine tapering. Overall, 90% of participating clinicians were satisfied with the program. Respondents who received in person detailing reported a higher likelihood of changing their behavior compared to respondents in the distance detailing group for five of seven content areas. While 90%-100% of respondents indicated they would continue to participate if the program were continued, the likelihood of participation declined if only distance approaches were offered. Conclusions We found strong support and satisfaction for the program among participating clinicians. Participants favored in-person approaches to distance interactions. Future efforts will be directed at quantitative methods for evaluating the economic and clinical effectiveness of detailing in rural

  20. Ceramicrete{trademark} Stabilization of CST Resin: ITP Alternative Phase III Feasibility Study

    Energy Technology Data Exchange (ETDEWEB)

    Langton, C A

    1998-12-07

    The Ceramicrete{trademark} waste form is a magnesium phosphate hydrate, which sets as the result of an acid-base reaction between KH{sub 2}PO{sub 4} and MgO in the presence of water. Based on the results of this feasibility study, this low temperature ceramic waste form is acceptable for stabilization of cesium loaded crystalline silicotitanate (CST) resin. The performance objective of CST stabilization is to convert a friable powdered resin into a monolithic form to improve handling and storage and to reduce the waste mobility. Advantages of this type of the CST-Ceramicrete{trademark} waste form include: room temperature processing of a fluid slurry, limited off gas, flexible mix designs, rapid setting, no free liquids, temperature tolerant and durable up to at least 90 degrees C. The Ceramicrete/220 waste form can be processed by in-container mixing or by batch mixing. Since a trace amount of free water will be associated with the wet resin in the CST-Ceramicrete{trademark} waste form, radiolysis of the free water may cause pressurization of the containers. Leaching tests were conducted to evaluate the CST-Ceramicrete{trademark} waste form performance relative to high-level waste glass. Results were very encouraging given that only one waste loading (50 wt. percent resin) was tested and that the leaching procedures were not fully optimized for a non-glass waste form. In general, the cesium leachability per the PCT test of the CST-Ceramicrete{trademark} waste was about 2X more than that of the ARM glass and about 200X more than the EA glass. For monolithic samples (MCC-1 test), the CST-Ceramicrete{trademark} waste form leached 4X to7X more cesium than the ARM glass. (The EA glass is not suited to monolithic leaching.) The CST-Ceramicrete{trademark} leaching results appear to be independent of curing temperature over the range 24 to 90 degrees C.

  1. Comparative study of alternative ORC-based combined power systems to exploit high temperature waste heat

    International Nuclear Information System (INIS)

    Highlights: • Three ORC-based combined systems for ICE exhaust waste heat recovery are studied. • A parametric investigation is conducted under several typical engine conditions. • Performance is evaluated considering six thermodynamic, techno-economic indexes. • DORC distinguishes among other solutions for its highest energy recovery capacity. • TEG–ORC system becomes attractive when exhaust temperature is relatively low. - Abstract: In this paper, various combined power systems which regard organic Rankine cycle (ORC) as bottoming cycle to recover engine’s high temperature exhaust heat are proposed. The topping recovery cycle includes steam Rankine cycle (RC), Brayton cycle (BC) and thermoelectric generator (TEG). Comprehensive evaluations are conducted under five typical engine conditions, ranging from high load to low load, and system performance is assessed in terms of many thermodynamic indexes, such as net output power, thermal efficiency, recovery efficiency and exergy efficiency. Besides that, the irreversibility of each component is also discussed in detail. R123, R245fa and R600a for ORC system are considered to analyze the influence of working fluids. Considering the system techno-economy, the turbine size parameter (SP) and heat transfer capacity (UA) are chosen as key indicators. The results show that compared with the other two investigated approaches, dual-loop ORC (DORC) possesses the highest energy exploitation capacity under the whole operating region, with a 5.57% increase of fuel economy under the rated condition, but its values of SP and UA are large as well. TEG–ORC becomes appealing while under the relatively low load

  2. Lifeline electric rates and alternative approaches to the problems of low-income ratepayers: ten case studies of rejected programs

    Energy Technology Data Exchange (ETDEWEB)

    1980-07-01

    This volume, Volume 3, contains ten case studies of non-implemented programs. It is noted that in Volume 2, the implemented lifeline programs, evolved as policy closely after the 1973 oil embargo; in contrast, the rejected programs were initiated about 4 years later and considered in a more-complex policy environment - after which time alternate methods of assisting low-income people had been developed. Specifically presented here are program summary, issue development, governmental process, and impact for the following: (a) Delaware Senate Bill 202; (b) Illinois House Bill 83; (c) Maine Legislative Document No. 1043; (d) Minnesota House File 1243; (e) New York Assembly Bill 12214; (f) New York Senate Bill 7013-A; (g) Rhode Island Resolution 79-H 5770-A; (h) South Dakota Senate Joint Resolution 9; (i) West Virginia House Bill 943; and (j) Wisconsin Assembly Bill 1250. 4 figures, 24 tables.

  3. Choquet integral as an alternative aggregation method to measure the overall academic performance of primary school students: A case study

    Science.gov (United States)

    Kasim, Maznah Mat; Abdullah, Siti Rohana Goh

    2014-07-01

    Many average methods are available to aggregate a set of numbers to become single number. However these methods do not consider the interdependencies between the criteria of the related numbers. This paper is highlighting the Choquet Integral method as an alternative aggregation method where the interdependency estimates between the criteria are comprised in the aggregation process. The interdependency values can be estimated by using lambda fuzzy measure method. By considering the interdependencies or interaction between the criteria, the resulted aggregated values are more meaningful as compared to the ones obtained by normal average methods. The application of the Choquet Integral is illustrated in a case study of finding the overall academic achievement of year six pupils in a selected primary school in a northern state of Malaysia.

  4. Scoping studies of the alternative options for defueling, packaging, shipping, and disposing of the TMI-2 spent fuel core

    International Nuclear Information System (INIS)

    A portion of this fuel will be shipped to nuclear facilities to perform detailed physical examinations. Removal of this fuel from the TMI-2 core is also a significant step in the eventual cleanup of this facility. The report presents a scoping study of the technical operations required for defueling and canning. The TMI fuel when canned could be stored in the spent fuel storage pool. After a period of on-site storage, it is expected that the bulk of the fuel will be shipped off-site for either storage or reprocessing. Evaluation is made of the technical, economic, and institutional factors associated with alternate approaches to disposition of this fuel. Recommendations are presented concerning future generic development tasks needed for the defueling, packaging, on-site shipping of this fuel

  5. Scoping studies of the alternative options for defueling, packaging, shipping, and disposing of the TMI-2 spent fuel core

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Robert T.

    1980-09-01

    A portion of this fuel will be shipped to nuclear facilities to perform detailed physical examinations. Removal of this fuel from the TMI-2 core is also a significant step in the eventual cleanup of this facility. The report presents a scoping study of the technical operations required for defueling and canning. The TMI fuel when canned could be stored in the spent fuel storage pool. After a period of on-site storage, it is expected that the bulk of the fuel will be shipped off-site for either storage or reprocessing. Evaluation is made of the technical, economic, and institutional factors associated with alternate approaches to disposition of this fuel. Recommendations are presented concerning future generic development tasks needed for the defueling, packaging, on-site shipping of this fuel.

  6. A scoping review of studies comparing the medication event monitoring system (MEMS) with alternative methods for measuring medication adherence.

    Science.gov (United States)

    El Alili, Mohamed; Vrijens, Bernard; Demonceau, Jenny; Evers, Silvia M; Hiligsmann, Mickael

    2016-07-01

    Different methods are available for measuring medication adherence. In this paper, we conducted a scoping review to identify and summarize evidence of all studies comparing the Medication Event Monitoring System (MEMS) with alternative methods for measuring medication adherence. A literature search was performed using the open database www.iAdherence.org that includes all original studies reporting findings from the MEMS. Papers comparing methods for measuring adherence to solid oral formulations were included. Data was extracted using a standardized extraction table. A total of 117 articles fulfilled the inclusion criteria, including 251 comparisons. Most frequent comparisons were against self-report (n = 119) and pill count (n = 59). Similar outcome measures were used in 210 comparisons (84%), among which 78 used dichotomous variables (adherent or not) and 132 used continuous measures (adherence expressed as percentage). Furthermore, 32% of all comparisons did not estimate adherence over the same coverage period and 44% of all comparisons did not use a statistical method or used a suboptimal one. Only eighty-seven (35%) comparisons had similar coverage periods, similar outcome measures and optimal statistical methods. Compared to MEMS, median adherence was grossly overestimated by 17% using self-report, by 8% using pill count and by 6% using rating. In conclusion, among all comparisons of MEMS versus alternative methods for measuring adherence, only a few used adequate comparisons in terms of outcome measures, coverage periods and statistical method. Researchers should therefore use stronger methodological frameworks when comparing measurement methods and be aware that non-electronic measures could lead to overestimation of medication adherence. PMID:27005306

  7. A scoping review of studies comparing the medication event monitoring system (MEMS) with alternative methods for measuring medication adherence.

    Science.gov (United States)

    El Alili, Mohamed; Vrijens, Bernard; Demonceau, Jenny; Evers, Silvia M; Hiligsmann, Mickael

    2016-07-01

    Different methods are available for measuring medication adherence. In this paper, we conducted a scoping review to identify and summarize evidence of all studies comparing the Medication Event Monitoring System (MEMS) with alternative methods for measuring medication adherence. A literature search was performed using the open database www.iAdherence.org that includes all original studies reporting findings from the MEMS. Papers comparing methods for measuring adherence to solid oral formulations were included. Data was extracted using a standardized extraction table. A total of 117 articles fulfilled the inclusion criteria, including 251 comparisons. Most frequent comparisons were against self-report (n = 119) and pill count (n = 59). Similar outcome measures were used in 210 comparisons (84%), among which 78 used dichotomous variables (adherent or not) and 132 used continuous measures (adherence expressed as percentage). Furthermore, 32% of all comparisons did not estimate adherence over the same coverage period and 44% of all comparisons did not use a statistical method or used a suboptimal one. Only eighty-seven (35%) comparisons had similar coverage periods, similar outcome measures and optimal statistical methods. Compared to MEMS, median adherence was grossly overestimated by 17% using self-report, by 8% using pill count and by 6% using rating. In conclusion, among all comparisons of MEMS versus alternative methods for measuring adherence, only a few used adequate comparisons in terms of outcome measures, coverage periods and statistical method. Researchers should therefore use stronger methodological frameworks when comparing measurement methods and be aware that non-electronic measures could lead to overestimation of medication adherence.

  8. Analysis of an alternative method for the study of bromeliad-associated fauna in plants with different foliar organization

    Directory of Open Access Journals (Sweden)

    Gerson A. Müller

    2010-12-01

    Full Text Available The efficiency of an alternative method of collection (by suction of water for the study of Culicidae and Chironomidae (Diptera, Scirtidae (Coleoptera and Coenagrionidae (Odonata in bromeliads with different foliar architecture in a restinga at Florianópolis, SC, Brazil, was studied. The alternative method was less efficient to collect Culicidae and Chironomidae (Wilcoxon test p 0.05 from Aechmea lindenii. This method was less efficient to collect insects of all groups from Vriesea friburgensis (Wilcoxon test p A eficiência do método alternativo de coleta (por sucção da água para o estudo de Culicidae e Chironomidae (Diptera, Scirtidae (Coleoptera e Coenagrionidae (Odonata em bromélias com diferentes estruturas foliares de restinga em Florianópolis, SC, Brasil, foi estudada. O método alternativo foi menos eficiente para coletar Culicidae e Chironomidae (teste de Wilcoxon p 0, 05 a partir de Aechmea lindenii. Esse foi menos eficiente para coletar insetos de todos os grupos a partir de Vriesea friburgensis (teste de Wilcoxon p < 0,05. O método alternativo se mostrou eficiente em estimar a diversidade desses insetos nas duas espécies de bromélias. A alta mobilidade das formas imaturas dos coleópteros e libélulas e a disponibilidade de apenas um tanque em Aechea lindenii, em contraste com as várias axilas e Vriesea friburgensis, facilitando a sucção destas formas imaturas provavelmente influenciaram os resultados. Os resultados indicam que o método de sucção não deve substituir o desmanche no estudo de Culicidae e Chironomidae; ele pode ser útil para a obtenção de formas imaturas de Scirtidae e Coenagrionidae em bromélias de um só tanque.

  9. The Cleveland Sorting Test: a preliminary study of an alternate form of the Wisconsin Card-Sorting Test.

    Science.gov (United States)

    Poreh, Amir; Pastel, Dan; Miller, Ashley; Levin, Jennifer

    2012-01-01

    During the past two decades, studies have repeatedly shown that the Wisconsin Card-Sorting Test (WCST) is not as sensitive to prefrontal-lobe functioning as was originally suspected. Specifically, both clinical and brain-imaging studies have shown that several distinct neural circuits contribute to one's ability to successfully complete different aspects of the test. Another limitation of the WCST is its length, which makes it difficult and frustrating for certain clinical populations. To address the above limitations, researchers have proposed the development of new indexes and the integration of an adaptive testing approach that will allow for the premature termination of the test. Unfortunately, given the proprietary nature of the WCST, none of the above recommendations have been adopted. The present preliminary study examined an alternate form of the 64-Item WCST (WCST-64), the Cleveland Sorting Test (CST-64). The normative data of the two measures as well as the total number of errors, perseverative responses, perseverative errors, and categories completed were compared using a repeated-measures design. Overall, the study supports psychometric approximation of the CST-64 and the WCST-64. Suggestions for future studies and modifications of the CST-64, including the use of recently proposed indexes and adaptive administration approaches, are provided.

  10. Assessment of Control Tissue for Gene and Protein Expression Studies: A Comparison of Three Alternative Lung Sources

    Directory of Open Access Journals (Sweden)

    Margaret R. Passmore

    2012-01-01

    Full Text Available The use of an appropriate control group in human research is essential in investigating the level of a pathological disorder. This study aimed to compare three alternative sources of control lung tissue and to determine their suitability for gene and protein expression studies. Gene and protein expression levels of the vascular endothelial growth factor (VEGF and gelatinase families and their receptors were measured using real-time reverse transcription polymerase chain reaction (RT-PCR and immunohistochemistry. The gene expression levels of VEGFA, placental growth factor (PGF, and their receptors, fms-related tyrosine kinase 1 (FLT1, and kinase insert domain receptor (KDR as well as matrix metalloproteinase-2 (MMP-2 and the inhibitors, tissue inhibitor of matrix metalloproteinase-1 (TIMP-1 and TIMP-2 were significantly higher in lung cancer resections. The gene expression level of MMP-9 was significantly lower in the corresponding samples. Altered protein expression was also detected, depending on the area assessed. The results of this study show that none of the three control groups studied are completely suitable for gene and protein studies associated with the VEGF and gelatinase families, highlighting the need for researchers to be selective in which controls they opt for.

  11. Vaginal dryness alternative treatments

    Science.gov (United States)

    ... a day. Soybeans contain plant-based substances called isoflavones. These substances have an effect on the body ... soy for vasomotor symptoms: the Herbal Alternatives for Menopause (HALT) Study. Menopause . 2008;15(1):51-58. ...

  12. Alternative fuel cycles

    International Nuclear Information System (INIS)

    Uranium resource utilization and economic considerations provide incentives to study alternative fuel cycles as future options to the PHWR natural uranium cycle. Preliminary studies to define the most favourable alternatives and their possible introduction dates are discussed. The important and uncertain components which influence option selection are reviewed, including nuclear capacity growth, uranium availability and demand, economic potential, and required technological developments. Finally, a summary of Ontario Hydro's program to further assess cycle selection and define development needs is given. (auth)

  13. Complementary and alternative medicine use and cost in functional bowel disorders: A six month prospective study in a large HMO

    Directory of Open Access Journals (Sweden)

    Drossman Douglas A

    2008-07-01

    Full Text Available Abstract Background Functional Bowel Disorders (FBD are chronic disorders that are difficult to treat and manage. Many patients and doctors are dissatisfied with the level of improvement in symptoms that can be achieved with standard medical care which may lead them to seek alternatives for care. There are currently no data on the types of Complementary and Alternative Medicine (CAM used for FBDs other than Irritable Bowel Syndrome (IBS, or on the economic costs of CAM treatments. The aim of this study is to determine prevalence, types and costs of CAM in IBS, functional diarrhea, functional constipation, and functional abdominal pain. Methods 1012 Patients with FBD were recruited through a health care maintenance organization and followed for 6 months. Questionnaires were used to ascertain: Utilization and expenditures on CAM, symptom severity (IBS-SS, quality of life (IBS-QoL, psychological distress (BSI and perceived treatment effectiveness. Costs for conventional medical care were extracted from administrative claims. Results CAM was used by 35% of patients, at a median yearly cost of $200. The most common CAM types were ginger, massage therapy and yoga. CAM use was associated with female gender, higher education, and anxiety. Satisfaction with physician care and perceived effectiveness of prescription medication were not associated with CAM use. Physician referral to a CAM provider was uncommon but the majority of patients receiving this recommendation followed their physician's advice. Conclusion CAM is used by one-third of FBD patients. CAM use does not seem to be driven by dissatisfaction with conventional care. Physicians should discuss CAM use and effectiveness with their patients and refer patients if appropriate.

  14. Alternative medicines for AIDS in resource-poor settings: Insights from exploratory anthropological studies in Asia and Africa

    NARCIS (Netherlands)

    A. Hardon; A. Desclaux; M. Egrot; E. Simon; E. Micollier; M. Kyakuwa

    2008-01-01

    The emergence of alternative medicines for AIDS in Asia and Africa was discussed at a satellite symposium and the parallel session on alternative and traditional treatments of the AIDSImpact meeting, held in Marseille, in July 2007. These medicines are heterogeneous, both in their presentation and i

  15. Immortalized mesenchymal stem cells: an alternative to primary mesenchymal stem cells in neuronal differentiation and neuroregeneration associated studies

    Directory of Open Access Journals (Sweden)

    Gong Min

    2011-11-01

    Full Text Available Abstract Background Mesenchymal stem cells (MSCs can be induced to differentiate into neuronal cells under appropriate cellular conditions and transplanted in brain injury and neurodegenerative diseases animal models for neuroregeneration studies. In contrast to the embryonic stem cells (ESCs, MSCs are easily subject to aging and senescence because of their finite ability of self-renewal. MSCs senescence seriously affected theirs application prospects as a promising tool for cell-based regenerative medicine and tissue engineering. In the present study, we established a reversible immortalized mesenchymal stem cells (IMSCs line by using SSR#69 retrovirus expressing simian virus 40 large T (SV40T antigen as an alternative to primary MSCs. Methods The retroviral vector SSR#69 expressing simian virus 40 large T (SV40T antigen was used to construct IMSCs. IMSCs were identified by flow cytometry to detect cell surface makers. To investigate proliferation and differentiation potential of IMSCs, cell growth curve determination and mesodermal trilineage differentiation tests were performed. Neuronal differentiation characteristics of IMSCs were detected in vitro. Before IMSCs transplantation, we excluded its tumorigenicity in nude mice firstly. The Morris water maze tests and shuttle box tests were performed five weeks after HIBD models received cells transplantation therapy. Results In this study, reversible IMSCs were constructed successfully and had the similar morphology and cell surface makers as primary MSCs. IMSCs possessed better ability of proliferation and anti-senescence compared with primary MSCs, while maintained multilineage differentiation capacity. Neural-like cells derived from IMSCs had similar expressions of neural-specific genes, protein expression patterns and resting membrane potential (RMP compared with their counterparts derived from primary MSCs. There was no bump formation in nude mice subcutaneously injected with IMSCs. IMSCs

  16. SPINAL ANESTHESIA A BETTER AND EFFECTIVE ALTERNATIVE TO GENERAL ANEASTHESIA IN SPINE SURGERIES: A PROSPECTIVE OPEN LABEL SINGLE ARM STUDY

    Directory of Open Access Journals (Sweden)

    Kumar Babu

    2014-11-01

    Full Text Available : INTRODUCTION: In all practical purposes various thoraco lumbar and lumbar surgeries like discectomy, laminectomy and spinal fusion procedures are usually performed under general anesthesia (GA. Our aim of this study is to assess whether spinal anesthesia is a better and effective alternative to general anesthesia in terms of economic advantage and functional recovery with both intra and post-operative heamodynamic stability. METHODS: In our study hundred patients with age group 25-45 yrs within the ASA criteria of class I-III were enrolled. All patients were randomly selected based on age, sex, ASS criteria, duration of surgery, heart rate (HR, mean arterial pressure (MAP, blood loss, previous history of risk factors and co morbidities. The severity of postoperative pain based on visual analogue scale (VAS and use of analgesics post operatively, were recorded. RESULTS: There were 41 males and 59 females. The mean age of the patient was 39.28±9.27 yrs. Six patients had hypertension, 11 with diabetes. Patients with ASA Grade I and II and III were 60, 34 and 6 respectively. There were no episodes of air way compromises, 2 patients had spinal aneasthesia failures, no incidence of post dural puncture headache, 3 patients had mean blood pressure fluctuations among them, one patient had post-operative paraperesis due to hematoma treated by immediate decompression, and 13 patients had usage of propofol sedation in terms of comfort. The duration of surgery (range was 77.25±22.44 min (40-120 Severity of postoperative pain after four hours of surgery on VAS was 3.24±0.46. Twenty two patients (22% required analgesics. Two patients had post-operative vomiting. CONCLUSIONS: In our study we have considered that spinal anesthesia for advantages such as less blood loss, intra operative blood pressure and heart rate changes, postoperative pain, quick functional recovery and lower incidence of pulmonary complications. Additionally, during spinal anesthesia

  17. Alternative loop rings

    CERN Document Server

    Goodaire, EG; Polcino Milies, C

    1996-01-01

    For the past ten years, alternative loop rings have intrigued mathematicians from a wide cross-section of modern algebra. As a consequence, the theory of alternative loop rings has grown tremendously. One of the main developments is the complete characterization of loops which have an alternative but not associative, loop ring. Furthermore, there is a very close relationship between the algebraic structures of loop rings and of group rings over 2-groups. Another major topic of research is the study of the unit loop of the integral loop ring. Here the interaction between loop rings and group ri

  18. Alternating irrigation water quality as a method to control solute concentrations and mass fluxes below irrigated fields: A numerical study

    Science.gov (United States)

    Russo, David

    2016-05-01

    The aim of the present numerical study was to extend the data-driven protocol for the control of soil salinity, to control chloride and nitrate concentrations and mass fluxes below agricultural fields irrigated with treated waste water (TWW). The protocol is based on alternating irrigation water quality between TWW and desalinized water (DSW), guided by solute concentrations at soil depth, zs. Two different schemes, the first requires measurements of soil solution concentrations of chloride and nitrate at zs, while, the second scheme requires only measurements of soil solution EC at zs, were investigated. For this purpose, 3-D numerical simulations of flow and transport were performed for variably saturated, spatially heterogeneous, flow domains located at two different field sites. The sites differ in crop type, irrigation method, and in their lithology; these differences, in turn, considerably affect the performance of the proposed schemes, expressed in terms of their ability to reduce solute concentrations that drained below the root zone. Results of the analyses suggest that the proposed data-driven schemes allow the use of low-quality water for irrigation, while minimizing the consumption of high-quality water to a level, which, for given climate, soil, crop, irrigation method, and water quality, may be determined by the allowable nitrate and chloride concentrations in the groundwater. The results of the present study indicate that with respect to the diminution of groundwater contamination by chloride and nitrate, the more data demanding, first scheme is superior the second scheme.

  19. Alternatives evaluation and decommissioning study on shielded transfer tanks at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    DeVore, J.R.; Hinton, R.R.

    1994-08-01

    The shielded transfer tanks (STTs) are five obsolete cylindrical shipping casks which were used to transport high specific activity radioactive solutions by rail during the 1960s and early 1970s. The STTs are currently stored at the Oak Ridge National Laboratory under a shed roof. This report is an evaluation to determine the preferred alternative for the final disposition of the five STTs. The decommissioning alternatives assessed include: (1) the no action alternative to leave the STTs in their present location with continued surveillance and maintenance; (2) solidification of contents within the tanks and holding the STTs in long term retrievable storage; (3) sale of one or more of the used STTs to private industry for use at their treatment facility with the remaining STTs processed as in Alternative 4; and (4) removal of tank contents for de-watering/retrievable storage, limited decontamination to meet acceptance criteria, smelting the STTs to recycle the metal through the DOE contaminated scrap metal program, and returning the shielding lead to the ORNL lead recovery program because the smelting contractor cannot reprocess the lead. To completely evaluate the alternatives for the disposition of the STTs, the contents of the tanks must be characterized. Shielding and handling requirements, risk considerations, and waste acceptance criteria all require that the radioactive inventory and free liquids residual in the STTs be known. Because characterization of the STT contents in the field was not input into a computer model to predict the probable inventory and amount of free liquid. The four alternatives considered were subjected to a numerical scoring procedure. Alternative 4, smelting the STTs to recycle the metal after removal/de-watering of the tank contents, had the highest score and is, therefore, recommended as the preferred alternative. However, if a buyer for one or more STT could be found, it is recommended that Alternative 3 be reconsidered.

  20. Alternatives evaluation and decommissioning study on shielded transfer tanks at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    International Nuclear Information System (INIS)

    The shielded transfer tanks (STTs) are five obsolete cylindrical shipping casks which were used to transport high specific activity radioactive solutions by rail during the 1960s and early 1970s. The STTs are currently stored at the Oak Ridge National Laboratory under a shed roof. This report is an evaluation to determine the preferred alternative for the final disposition of the five STTs. The decommissioning alternatives assessed include: (1) the no action alternative to leave the STTs in their present location with continued surveillance and maintenance; (2) solidification of contents within the tanks and holding the STTs in long term retrievable storage; (3) sale of one or more of the used STTs to private industry for use at their treatment facility with the remaining STTs processed as in Alternative 4; and (4) removal of tank contents for de-watering/retrievable storage, limited decontamination to meet acceptance criteria, smelting the STTs to recycle the metal through the DOE contaminated scrap metal program, and returning the shielding lead to the ORNL lead recovery program because the smelting contractor cannot reprocess the lead. To completely evaluate the alternatives for the disposition of the STTs, the contents of the tanks must be characterized. Shielding and handling requirements, risk considerations, and waste acceptance criteria all require that the radioactive inventory and free liquids residual in the STTs be known. Because characterization of the STT contents in the field was not input into a computer model to predict the probable inventory and amount of free liquid. The four alternatives considered were subjected to a numerical scoring procedure. Alternative 4, smelting the STTs to recycle the metal after removal/de-watering of the tank contents, had the highest score and is, therefore, recommended as the preferred alternative. However, if a buyer for one or more STT could be found, it is recommended that Alternative 3 be reconsidered

  1. Alternative crops

    International Nuclear Information System (INIS)

    Surplus cereal production in the EEC and decreasing product prices, mainly for cereals, has prompted considerable interest for new earnings in arable farming. The objective was to examine whether suggested new crops (fibre, oil, medicinal and alternative grains crops) could be considered as real alternatives. Whether a specific crop can compete economically with cereals and whether there is a market demand for the crop is analyzed. The described possibilities will result in ca. 50,000 hectares of new crops. It is expected that they would not immediately provide increased earnings, but in the long run expected price developments are more positive than for cereals. The area for new crops will not solve the current surplus cereal problem as the area used for new crops is only 3% of that used for cereals. Preconditions for many new crops is further research activities and development work as well as the establishment of processing units and organizational initiatives. Presumably, it is stated, there will then be a basis for a profitable production of new crops for some farmers. (AB) (47 refs.)

  2. BLENDED LEARNING (BL AS PEDAGOGICAL ALTERNATIVE TO TEACH BUSINESS COMMUNICATION COURSE: Case Study of UUM Executive Diploma Program

    Directory of Open Access Journals (Sweden)

    Hisham DZAKIRIA

    2012-07-01

    Full Text Available Globally, blended learning (BL technologies have been increasingly applied in a variety of fields, both public and private sectors. In recent years, universities, public and private businesses and organizations are among those employing blended learning methods and technologies in training and re-training of professionals in the workforce. In Malaysia, the increasing use of blended learning to enhance learning and enriching of soft skills among professionals and individuals in the work place is evident. The advancement of technology is an onset to many new avenues and tool for learning and teaching, and it is the coalescing of these various technologies with particular pedagogy or andragogy has helped to popularize BL. However, when an institution makes the critical choice of delivery methods, it is pertinent that the university needs to consider various success factors. One in particular is student-centered approach that entails the need to understand the students as the beneficiary of learning, and the support system they need to help them learn. This qualitative study reports in detail the experience of a small group of students undertaking Executive Diplomas at Executive Development Centre (EDC, Universiti Utara Malaysia as they progress through their Executive program. This paper looks at learning experiences as described by the learners- it is their story, their experience, and their perspective. This study suggests that BL offered a comfortable middle ground, and has lots of potential in higher education in Malaysia. It is a pedagogical alternative that could play a significant role not only for teaching Business Communication, but has the potential to promote lifelong learning initiatives in Malaysia in a much meaningful and inviting way. Although this study shows that BL contributed a significant and meaningful learning particularly for adult learners, it needs more definitive studies. Such information can be used to guide policy makers

  3. Utilization of reconstructed cultured human skin models as an alternative skin for permeation studies of chemical compounds

    OpenAIRE

    Kano, Satoshi; 藤堂, 浩明; 杉江, 謙一; 藤本, 英哲; 中田, 圭一; 徳留, 嘉寛; 橋本, フミ惠; 杉林, 堅次

    2010-01-01

    Two reconstructed human skin models, EpiskinSM and EpiDermTM, have been approved as alternative membranes for skin corrosive/irritation experiments due to their close correlation with animal skin. Such reconstructed human skin models were evaluated as alternative membranes for skin permeation experiments. Seven drugs with different lipophilicities and almost the same molecular weight were used as test penetrants. Relationships were investigated between permeability coefficients (P values) of ...

  4. The role of complementary and alternative medicine (CAM in Germany – A focus group study of GPs

    Directory of Open Access Journals (Sweden)

    Rosemann Thomas

    2008-06-01

    Full Text Available Abstract Background There has been a marked increase in the use of complementary and alternative medicine (CAM in recent years worldwide. In Germany, apart from 'Heilpraktiker' (= state-licensed, non-medical CAM practitioners, some general practitioners (GPs provide CAM in their practices. This paper aims to explore the attitudes of GPs about the role of CAM in Germany, in relation to the healthcare system, quality of care, medical education and research. Furthermore, experiences of GPs integrating CAM in their daily practice were explored. Methods Using a qualitative methodological approach 3 focus groups with a convenience sample of 17 GPs were conducted. The discussions were transcribed verbatim and analysed using qualitative content analysis. Results The majority of the participating GPs had integrated one or more CAM therapies into their every-day practice. Four key themes were identified based on the topics covered in the focus groups: the role of CAM within the German healthcare system, quality of care, education and research. Within the theme 'role of CAM within the healthcare system' there were five categories: integration of CAM, CAM in the Statutory Health Insurance, modernisation of the Statutory Health Insurance Act, individual healthcare services and 'Heilpraktiker'. Regarding quality of care there were two broad groups of GPs: those who thought patients would benefit from standardizing CAM and those who feared that quality control would interfere with the individual approach of CAM. The main issues identified relating to research and education were the need for the development of alternative research strategies and the low quality of existing CAM education respectively. Conclusion The majority of the participating GPs considered CAM as a reasonable complementary approach within primary care. The study increased our understanding of GPs attitudes about the role of CAM within the German healthcare system and the use of

  5. A comparative study between different alternatives to prepare gaseous standards for calibrating UV-Ion Mobility Spectrometers.

    Science.gov (United States)

    Criado-García, Laura; Garrido-Delgado, Rocío; Arce, Lourdes; Valcárcel, Miguel

    2013-07-15

    An UV-Ion Mobility Spectrometer is a simple, rapid, inexpensive instrument widely used in environmental analysis among other fields. The advantageous features of its underlying technology can be of great help towards developing reliable, economical methods for determining gaseous compounds from gaseous, liquid and solid samples. Developing an effective method using UV-Ion Mobility Spectrometry (UV-IMS) to determine volatile analytes entails using appropriate gaseous standards for calibrating the spectrometer. In this work, two home-made sample introduction systems (SISs) and a commercial gas generator were used to obtain such gaseous standards. The first home-made SIS used was a static head-space to measure compounds present in liquid samples and the other home-made system was an exponential dilution set-up to measure compounds present in gaseous samples. Gaseous compounds generated by each method were determined on-line by UV-IMS. Target analytes chosen for this comparative study were ethanol, acetone, benzene, toluene, ethylbenzene and xylene isomers. The different alternatives were acceptable in terms of sensitivity, precision and selectivity.

  6. Use of Complementary and Alternative Medicine in Children with Cancer: A Study at a Swiss University Hospital.

    Directory of Open Access Journals (Sweden)

    Tatjana Magi

    Full Text Available Though complementary and alternative medicine (CAM are frequently used by children and adolescents with cancer, there is little information on how and why they use it. This study examined prevalence and methods of CAM, the therapists who applied it, reasons for and against using CAM and its perceived effectiveness. Parent-perceived communication was also evaluated. Parents were asked if medical staff provided information on CAM to patients, if parents reported use of CAM to physicians, and what attitude they thought physicians had toward CAM.All childhood cancer patients treated at the University Children's Hospital Bern between 2002-2011 were retrospectively surveyed about their use of CAM.Data was collected from 133 patients (response rate: 52%. Of those, 53% had used CAM (mostly classical homeopathy and 25% of patients received information about CAM from medical staff. Those diagnosed more recently were more likely to be informed about CAM options. The most frequent reason for choosing CAM was that parents thought it would improve the patient's general condition. The most frequent reason for not using CAM was lack of information. Of those who used CAM, 87% perceived positive effects.Since many pediatric oncology patients use CAM, patients' needs should be addressed by open communication between families, treating oncologists and CAM therapists, which will allow parents to make informed and safe choices about using CAM.

  7. Predictors for adolescent visits to practitioners of complementary and alternative medicine in a total population (the Young-HUNT Studies.

    Directory of Open Access Journals (Sweden)

    Aslak Steinsbekk

    Full Text Available AIM: To investigate the factors predicting adolescent visits to practitioners of complementary and alternative medicine (CAM. METHODS: A longitudinal cohort study conducted in an adolescent total population in Central Norway (The Nord-Trøndelag Health Studies (HUNT. In Young-HUNT 1, all inhabitants aged 13 to 19 years (N = 8944, 89% response rate were invited to participate, and the youngest group (13 to 15 year olds was surveyed again 4 years later (Young-HUNT 2, N = 2429, 82% response rate. The participants completed a comprehensive questionnaire on health and life style which included a question regarding visits to a CAM practitioner in the last 12 months. RESULTS: One in eleven (8.7%, 95%CI 7.6-9.8% had visited a CAM practitioner, an increase of 26% in 4 years (1.8% points. The final multivariable analysis predicted increased odds of an adolescent becoming a CAM visitor four years later (p<0.05 if she or he had previously visited a CAM practitioner (adjOR 3.4, had musculoskeletal pain (adjOR 1.5, had migraine (adjOR 2.3, used asthma medicines (adjOR 1.8 or suffered from another disease lasting more than three months (adjOR 2.1. Being male predicted reduced odds of visiting a CAM practitioner in the future (adjOR 0.6. CONCLUSION: We can conclude from this study that future visits to a CAM practitioner are predicted by both predisposing factors (being female, having visited a CAM practitioner previously and medical need factors (having had musculoskeletal pain, migraine, used asthma medicines or experienced another disease lasting more than three months. None of the specific variables associated with CAM visits were predictive for CAM visits four years later.

  8. A Prospective, Multicenter Study of Complementary/Alternative Medicine (CAM) Utilization During Definitive Radiation for Breast Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Moran, Meena S., E-mail: meena.moran@yale.edu [Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut (United States); Department of Radiation Therapy, William W. Backus Hospital, Norwich, Connecticut (United States); Ma Shuangge [Department of Epidemiology and Public Health, Yale University, New Haven, Connecticut (United States); Jagsi, Reshma [University of Michigan, Department of Radiation Oncology, Ann Arbor, MI (United States); Yang, Tzu-I Jonathan [Yale University School of Medicine, New Haven, Connecticut (United States); Higgins, Susan A. [Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut (United States); Department of Radiation Therapy, Shoreline Medical Center, Guilford, Connecticut (United States); Weidhaas, Joanne B. [Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut (United States); Wilson, Lynn D. [Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut (United States); Department of Radiation Therapy, Lawrence and Memorial Hospital, New London, Connecticut (United States); Lloyd, Shane [Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut (United States); Peschel, Richard [Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut (United States); Department of Radiation Therapy, Lawrence and Memorial Hospital, New London, Connecticut (United States); Gaudreau, Bryant [Department of Radiation Therapy, William W. Backus Hospital, Norwich, Connecticut (United States); Rockwell, Sara [Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut (United States)

    2013-01-01

    Purpose: Although complementary and alternative medicine (CAM) utilization in breast cancer patients is reported to be high, there are few data on CAM practices in breast patients specifically during radiation. This prospective, multi-institutional study was conducted to define CAM utilization in breast cancer during definitive radiation. Materials/Methods: A validated CAM instrument with a self-skin assessment was administered to 360 Stage 0-III breast cancer patients from 5 centers during the last week of radiation. All data were analyzed to detect significant differences between users/nonusers. Results: CAM usage was reported in 54% of the study cohort (n=194/360). Of CAM users, 71% reported activity-based CAM (eg, Reiki, meditation), 26% topical CAM, and 45% oral CAM. Only 16% received advice/counseling from naturopathic/homeopathic/medical professionals before initiating CAM. CAM use significantly correlated with higher education level (P<.001), inversely correlated with concomitant hormone/radiation therapy use (P=.010), with a trend toward greater use in younger patients (P=.066). On multivariate analysis, level of education (OR: 6.821, 95% CI: 2.307-20.168, P<.001) and hormones/radiation therapy (OR: 0.573, 95% CI: 0.347-0.949, P=.031) independently predicted for CAM use. Significantly lower skin toxicity scores were reported in CAM users vs nonusers, respectively (mild: 34% vs 25%, severe: 17% vs 29%, P=.017). Conclusion: This is the first prospective study to assess CAM practices in breast patients during radiation, with definition of these practices as the first step for future investigation of CAM/radiation interactions. These results should alert radiation oncologists that a large percentage of breast cancer patients use CAM during radiation without disclosure or consideration for potential interactions, and should encourage increased awareness, communication, and documentation of CAM practices in patients undergoing radiation treatment for breast

  9. A Prospective, Multicenter Study of Complementary/Alternative Medicine (CAM) Utilization During Definitive Radiation for Breast Cancer

    International Nuclear Information System (INIS)

    Purpose: Although complementary and alternative medicine (CAM) utilization in breast cancer patients is reported to be high, there are few data on CAM practices in breast patients specifically during radiation. This prospective, multi-institutional study was conducted to define CAM utilization in breast cancer during definitive radiation. Materials/Methods: A validated CAM instrument with a self-skin assessment was administered to 360 Stage 0-III breast cancer patients from 5 centers during the last week of radiation. All data were analyzed to detect significant differences between users/nonusers. Results: CAM usage was reported in 54% of the study cohort (n=194/360). Of CAM users, 71% reported activity-based CAM (eg, Reiki, meditation), 26% topical CAM, and 45% oral CAM. Only 16% received advice/counseling from naturopathic/homeopathic/medical professionals before initiating CAM. CAM use significantly correlated with higher education level (P<.001), inversely correlated with concomitant hormone/radiation therapy use (P=.010), with a trend toward greater use in younger patients (P=.066). On multivariate analysis, level of education (OR: 6.821, 95% CI: 2.307-20.168, P<.001) and hormones/radiation therapy (OR: 0.573, 95% CI: 0.347-0.949, P=.031) independently predicted for CAM use. Significantly lower skin toxicity scores were reported in CAM users vs nonusers, respectively (mild: 34% vs 25%, severe: 17% vs 29%, P=.017). Conclusion: This is the first prospective study to assess CAM practices in breast patients during radiation, with definition of these practices as the first step for future investigation of CAM/radiation interactions. These results should alert radiation oncologists that a large percentage of breast cancer patients use CAM during radiation without disclosure or consideration for potential interactions, and should encourage increased awareness, communication, and documentation of CAM practices in patients undergoing radiation treatment for breast

  10. Alternative Energies

    Energy Technology Data Exchange (ETDEWEB)

    Planting, A.; De saint Jacob, Y.; Verwijs, H.; Belin, H.; Preesman, L.

    2009-03-15

    In two articles, one interview and one column attention is paid to alternative energies. The article 'A new light on saving energy' discusses the option to save energy by modernising lighting systems in urban areas. The column 'View from Paris' focuses on investment decisions in France with regard to renewable energy and energy savings. The article 'Europe turns a blind eye to big battery' discusses developments in batteries to store energy. The interview concerns fuel cell expert and formerly President of UTC Power Jan van Dokkum. The last article gives a brief overview of the European Energy Research Alliance (EERA) and the challenges this alliance will have to face with regard to climate change and energy security.

  11. Energy alternatives

    International Nuclear Information System (INIS)

    English. A special committe of the Canadian House of Commons was established on 23 May 1980 to investigate the use of alternative energy sources such as 'gasohol', liquified coal, solar energy, methanol, wind and tidal power, biomass, and propane. In its final report, the committee envisions an energy system for Canada based on hydrogen and electricity, using solar and geothermal energy for low-grade heat. The committe was not able to say which method of generating electricty would dominate in the next century, although it recommends that fossil fuels should not be used. The fission process is not specifically discussed, but the outlook for fusion was investigated, and continued governmental support of fusion research is recommended. The report proposes some improvements in governmental energy organizations and programs

  12. Association of Health Literacy with Complementary and Alternative Medicine Use: A Cross-Sectional Study in Adult Primary Care Patients

    Directory of Open Access Journals (Sweden)

    Bains Sujeev S

    2011-12-01

    Full Text Available Abstract Background In the United States, it is estimated that 40% of adults utilize complementary and alternative medicine (CAM therapies. Recently, national surveys report that over 90 million adults have inadequate health literacy. To date, no study has assessed health literacy and its effect on CAM use. The primary objective of this study was to assess the relationship between health literacy and CAM use independent of educational attainment. Second objective was to evaluate the differential effect of health literacy on CAM use by race. Methods 351 patients were recruited from an outpatient primary care clinic. Validated surveys assessed CAM use (I-CAM-Q, health literacy (REALM-R, and demographic information. We compared demographics by health literacy (adequate vs. inadequate and overall and individual CAM categories by health literacy using chi square statistics. We found a race by health literacy interaction and ran sequential logistic regression models stratified by race to test the association between health literacy and overall CAM use (Model 1, Model 1 + education (Model 2, and Model 2 + other demographic characteristics (Model 3. We reported the adjusted effect of health literacy on CAM use for both whites and African Americans separately. Results 75% of the participants had adequate literacy and 80% used CAM. CAM use differed by CAM category. Among whites, adequate health literacy was significantly associated with increased CAM use in both unadjusted (Model 1, OR 7.68; p = 0.001 and models adjusted for education (Model 2, OR 7.70; p = 0.002 and other sociodemographics (Model 3, OR 9.42; p = 0.01. Among African Americans, adequate health literacy was not associated with CAM use in any of the models. Conclusions We found a race by literacy interaction suggesting that the relationship between health literacy and CAM use differed significantly by race. Adequate health literacy among whites is associated with increased CAM use, but not

  13. A preliminary study on Oxya fuscovittata (Marschall) as an alternative nutrient supplement in the diets of Poecillia sphenops (Valenciennes).

    Science.gov (United States)

    Ganguly, Arijit; Chakravorty, Ranita; Sarkar, Angshuman; Mandal, Dipak K; Haldar, Parimalendu; Ramos-Elorduy, Julieta; Moreno, Jose Manuel Pino

    2014-01-01

    Growth of the ornamental fish industry is being hindered by the scarcity of low cost feed; hence alternative protein supplements should be explored. In this context the present study aims to evaluate whether the grasshopper Oxya fuscovittata could be used as a supplement for fish meal in the diets of Poecillia sphenops, which is one of the most common ornamental fishes worldwide. The present work is divided into three phases: In the first phase proximate composition of the grasshopper is obtained and five diets are prepared where fish meal is gradually replaced by Oxya meal and named as control, D1, D2, D3 and D4. All the diets are formulated on iso-nitrogenous basis where the protein percentage is fixed at 400 g/kg. The second phase deals with feeding trial and in the third phase all the data of the feeding trial are subjected to a linear model. The feeding trial shows that the control, D1 and D2 fed fishes have almost similar results. The linear model proves that the variation in the indices are mainly due to replacement of fish meal by Oxya meal, not due to the variations of rice husk and mustard oil cake that are also used to formulate the diets of the present study. From the results two Oxya supplemented diets, i.e. D1 and D2 are proved to be almost equivalent to the control diet. Hence it is concluded that Oxya meal is able to replace 25% to 50% of fish meal from the diets of P. sphenops. PMID:25383946

  14. A preliminary study on Oxya fuscovittata (Marschall as an alternative nutrient supplement in the diets of Poecillia sphenops (Valenciennes.

    Directory of Open Access Journals (Sweden)

    Arijit Ganguly

    Full Text Available Growth of the ornamental fish industry is being hindered by the scarcity of low cost feed; hence alternative protein supplements should be explored. In this context the present study aims to evaluate whether the grasshopper Oxya fuscovittata could be used as a supplement for fish meal in the diets of Poecillia sphenops, which is one of the most common ornamental fishes worldwide. The present work is divided into three phases: In the first phase proximate composition of the grasshopper is obtained and five diets are prepared where fish meal is gradually replaced by Oxya meal and named as control, D1, D2, D3 and D4. All the diets are formulated on iso-nitrogenous basis where the protein percentage is fixed at 400 g/kg. The second phase deals with feeding trial and in the third phase all the data of the feeding trial are subjected to a linear model. The feeding trial shows that the control, D1 and D2 fed fishes have almost similar results. The linear model proves that the variation in the indices are mainly due to replacement of fish meal by Oxya meal, not due to the variations of rice husk and mustard oil cake that are also used to formulate the diets of the present study. From the results two Oxya supplemented diets, i.e. D1 and D2 are proved to be almost equivalent to the control diet. Hence it is concluded that Oxya meal is able to replace 25% to 50% of fish meal from the diets of P. sphenops.

  15. Role of Kekul\\'e and Non-Kekul\\'e Structures in the Radical Character of Alternant Polycyclic Aromatic Hydrocarbons: A TAO-DFT Study

    CERN Document Server

    Yeh, Chia-Nan

    2016-01-01

    We investigate the role of Kekul\\'e and non-Kekul\\'e structures in the radical character of alternant polycyclic aromatic hydrocarbons (PAHs) using thermally-assisted-occupation density functional theory (TAO-DFT), an efficient electronic structure method for the study of large ground-state systems with strong static correlation effects. Our results reveal that the studies of Kekul\\'e and non-Kekul\\'e structures qualitatively describe the radical character of alternant PAHs, which could be useful when electronic structure calculations are infeasible due to the expensive computational cost. In addition, our results support previous findings on the increase in radical character with increasing system size. For alternant PAHs with the same number of aromatic rings, the geometrical arrangements of aromatic rings are responsible for their radical character.

  16. Role of Kekulé and Non-Kekulé Structures in the Radical Character of Alternant Polycyclic Aromatic Hydrocarbons: A TAO-DFT Study

    Science.gov (United States)

    Yeh, Chia-Nan; Chai, Jeng-Da

    2016-07-01

    We investigate the role of Kekulé and non-Kekulé structures in the radical character of alternant polycyclic aromatic hydrocarbons (PAHs) using thermally-assisted-occupation density functional theory (TAO-DFT), an efficient electronic structure method for the study of large ground-state systems with strong static correlation effects. Our results reveal that the studies of Kekulé and non-Kekulé structures qualitatively describe the radical character of alternant PAHs, which could be useful when electronic structure calculations are infeasible due to the expensive computational cost. In addition, our results support previous findings on the increase in radical character with increasing system size. For alternant PAHs with the same number of aromatic rings, the geometrical arrangements of aromatic rings are responsible for their radical character.

  17. Use of complementary and alternative medicine by patients with localized prostate carcinoma. Study at a single institute in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Yoshimura, Koji; Ichioka, Kentaro; Terada, Naoki; Terai, Akito [Kurashiki Central Hospital, Okayama (Japan); Arai, Yoichi [Tohoku Univ., Sendai (Japan). Graduate School of Medicine

    2003-02-01

    The use of complementary/alternative medicine (CAM) has recently received considerable attention throughout the world. We evaluated the prevalence and predictors of CAM use among Japanese patients with localized prostate cancer. A total of 177 patients with localized prostate carcinoma underwent radical retropubic prostatecotomy or external beam radiation therapy between January 1994 and January 2001. Of them, 138 (78%) answered a self-administered questionnaire on CAM use and were eligible for this study. The overall prevalence, types of CAM used, and costs of CAM were assessed. The effects of age, prostate-specific antigen (PSA) level, clinical stage, pretreatment Gleason score, patients' income, patients' final educational status, and general health-related quality of life at baseline and 1 year after treatment, as estimated using the European Organization for Research and Treatment of Cancer Prostate Cancer Quality of Life Questionnaire on the prevalence of CAM use, were evaluated. Twenty-seven patients (20%) had once used or had been using some types of CAM. Herbal medicine and vitamins were the most common types of CAM used. Preoperative Gleason score was significantly associated with CAM use, as determined by the {chi}''2 test (P0.0198), and PSA level and posttreatment physical function domain were marginally associated with CAM use, as determined by the Mann-Whitney U-test (P=0.0734 and P=0.0597, respectively). Patient age, income, and final educational status had no impact on CAM use. A relatively small proportion of Japanese patients with localized prostate cancer have tried CAM compared with the proportions of patients described in previous reports from Western countries. (author)

  18. Use of complementary and alternative medicine by patients with localized prostate carcinoma. Study at a single institute in Japan

    International Nuclear Information System (INIS)

    The use of complementary/alternative medicine (CAM) has recently received considerable attention throughout the world. We evaluated the prevalence and predictors of CAM use among Japanese patients with localized prostate cancer. A total of 177 patients with localized prostate carcinoma underwent radical retropubic prostatecotomy or external beam radiation therapy between January 1994 and January 2001. Of them, 138 (78%) answered a self-administered questionnaire on CAM use and were eligible for this study. The overall prevalence, types of CAM used, and costs of CAM were assessed. The effects of age, prostate-specific antigen (PSA) level, clinical stage, pretreatment Gleason score, patients' income, patients' final educational status, and general health-related quality of life at baseline and 1 year after treatment, as estimated using the European Organization for Research and Treatment of Cancer Prostate Cancer Quality of Life Questionnaire on the prevalence of CAM use, were evaluated. Twenty-seven patients (20%) had once used or had been using some types of CAM. Herbal medicine and vitamins were the most common types of CAM used. Preoperative Gleason score was significantly associated with CAM use, as determined by the χ''2 test (P0.0198), and PSA level and posttreatment physical function domain were marginally associated with CAM use, as determined by the Mann-Whitney U-test (P=0.0734 and P=0.0597, respectively). Patient age, income, and final educational status had no impact on CAM use. A relatively small proportion of Japanese patients with localized prostate cancer have tried CAM compared with the proportions of patients described in previous reports from Western countries. (author)

  19. Validity study of Animal-City Alternating Form Fluency Test in the identification of mild cognitive impairment and Alzheimer's disease

    Directory of Open Access Journals (Sweden)

    Yun-bo SHI

    2015-07-01

    Full Text Available Objective To identify the sensitivity and specificity of Animal-City Alternating Form Fluency Test (ACFT differentiating mild cognitive impairment (MCI and Alzheimer's disease (AD from normal controls.  Methods A total of 121 MCI patients, 104 AD patients and 104 healthy controls, who were matched in sex, age and education level, were enrolled in this study. They performed Animal Category Verbal Fluency Test (AFT, City Category Verbal Fluency Test (CFT and ACFT. A series of standard neuropsychological tests were also administered to reflect episodic memory, verbal ability, working memory, executive function and processing speed. The validity and related influencing factors of ACFT was evaluated.  Results Compared with control group, the ACFT correct number in MCI and AD groups reduced significantly (P = 0.000, 0.000. Receiver operating characteristic (ROC curve revealed the sensitivity and specificity of ACFT in discriminating MCI (P = 0.012, 0.030 and AD (P = 0.004, 0.003 from normal controls were higher than those of AFT and CFT. There was no correlation of correct number in ACFT with age and education (P > 0.05, for all. The correlations of ACFT with Stroop Color-Word Test (SCWT, Digital Symbol Substitution Test (DSST, Shape Trail Test (STT and Digit Span Test (DS, all of which reflected attention and executive function, were significantly closer than those of AFT and CFT (P < 0.05, for all. Conclusions ACFT is more efficient in early cognitive impairment identification than the other traditional category verbal fluency tests. It is a new variant form of category verbal fluency test that could assess cognitive function and could be broadly applied in clinical practice. DOI: 10.3969/j.issn.1672-6731.2015.07.010

  20. Alternatives to F-Test in One Way ANOVA in case of heterogeneity of variances (a simulation study

    Directory of Open Access Journals (Sweden)

    Karl Moder

    2010-12-01

    Full Text Available Several articles deal with the effects of inhomogeneous variances in one way analysis of variance (ANOVA. A very early investigation of this topic was done by Box (1954. He supposed, that in balanced designs with moderate heterogeneity of variances deviations of the empirical type I error rate (on experiments based realized α to the nominal one (predefined α for H0 are small. Similar conclusions are drawn by Wellek (2003. For not so moderate heterogeneity (e.g. σ1:σ2:...=3:1:... Moder (2007 showed, that empirical type I error rate is far beyond the nominal one, even with balanced designs. In unbalanced designs the difficulties get bigger. Several attempts were made to get over this problem. One proposal is to use a more stringent α level (e.g. 2.5% instead of 5% (Keppel & Wickens, 2004. Another recommended remedy is to transform the original scores by square root, log, and other variance reducing functions (Keppel & Wickens, 2004, Heiberger & Holland, 2004. Some authors suggest the use of rank based alternatives to F-test in analysis of variance (Vargha & Delaney, 1998. Only a few articles deal with two or multifactorial designs. There is some evidence, that in a two or multi-factorial design type I error rate is approximately met if the number of factor levels tends to infinity for a certain factor while the number of levels is fixed for the other factors (Akritas & S., 2000, Bathke, 2004.The goal of this article is to find an appropriate location test in an oneway analysis of variance situation with inhomogeneous variances for balanced and unbalanced designs based on a simulation study.

  1. Of woods and webs: possible alternatives to the tree of life for studying genomic fluidity in E. coli

    Directory of Open Access Journals (Sweden)

    Lapointe François-Joseph

    2011-07-01

    Full Text Available Abstract Background We introduce several forest-based and network-based methods for exploring microbial evolution, and apply them to the study of thousands of genes from 30 strains of E. coli. This case study illustrates how additional analyses could offer fast heuristic alternatives to standard tree of life (TOL approaches. Results We use gene networks to identify genes with atypical modes of evolution, and genome networks to characterize the evolution of genetic partnerships between E. coli and mobile genetic elements. We develop a novel polychromatic quartet method to capture patterns of recombination within E. coli, to update the clanistic toolkit, and to search for the impact of lateral gene transfer and of pathogenicity on gene evolution in two large forests of trees bearing E. coli. We unravel high rates of lateral gene transfer involving E. coli (about 40% of the trees under study, and show that both core genes and shell genes of E. coli are affected by non-tree-like evolutionary processes. We show that pathogenic lifestyle impacted the structure of 30% of the gene trees, and that pathogenic strains are more likely to transfer genes with one another than with non-pathogenic strains. In addition, we propose five groups of genes as candidate mobile modules of pathogenicity. We also present strong evidence for recent lateral gene transfer between E. coli and mobile genetic elements. Conclusions Depending on which evolutionary questions biologists want to address (i.e. the identification of modules, genetic partnerships, recombination, lateral gene transfer, or genes with atypical evolutionary modes, etc., forest-based and network-based methods are preferable to the reconstruction of a single tree, because they provide insights and produce hypotheses about the dynamics of genome evolution, rather than the relative branching order of species and lineages. Such a methodological pluralism - the use of woods and webs - is to be encouraged to

  2. Moving virtuality into reality: A comparison study of the effectiveness of traditional and alternative assessments of learning in a multisensory, fully immersive physics program

    Science.gov (United States)

    Gamor, Keysha Ingram

    This paper contains a research study that investigated the relative efficacy of using both a traditional paper-and-pencil assessment instrument and an alternative, virtual reality (VR) assessment instrument to assist educators and/or instructional designers in measuring learning in a virtual reality learning environment. To this end, this research study investigated assessment in VR, with the goal of analyzing aspects of student learning in VR that are feasible to access or capture by traditional assessments and alternative assessments. The researcher also examined what additional types of learning alternative assessments may offer. More specifically, this study compared the effectiveness of a traditional method with an alternative (performance-based) method of assessment that was used to examine the ability of the tools to accurately evidence the levels of students' understanding and learning. The domain area was electrostatics, a complex, abstract multidimensional concept, with which students often experience difficulty. Outcomes of the study suggest that, in the evaluation of learning in an immersive VR learning environment, assessments would most accurately manifest student learning if the assessment measure matched the learning environment itself. In this study, learning and assessing in the VR environment yielded higher final test scores than learning in VR and testing with traditional paper-and-pencil. Being able to transfer knowledge from a VR environment to other situations is critical in demonstrating the overall level of understanding of a concept. For this reason, the researcher recommends a combination of testing measures to enhance understanding of complex, abstract concepts.

  3. The development of an in vitro model for studying mechanisms of nephrotoxicity as an alternative for animal experiments.

    NARCIS (Netherlands)

    Mertens, J.J.W.M.

    1991-01-01

    SUMMARYPresently in our society animal tests still form the main starting point for the assessment of the possible risks of chemicals with regard to human and animal health. For scientific. economic, and ethical reasons. attempts are undertaken continuously to develop cell models as alternatives to

  4. Primary Healthcare Provider Knowledge, Beliefs and Clinic-Based Practices Regarding Alternative Tobacco Products and Marijuana: A Qualitative Study

    Science.gov (United States)

    Bascombe, Ta Misha S.; Scott, Kimberly N.; Ballard, Denise; Smith, Samantha A.; Thompson, Winifred; Berg, Carla J.

    2016-01-01

    Use prevalence of alternative tobacco products and marijuana has increased dramatically. Unfortunately, clinical guidelines have focused on traditional cigarettes with limited attention regarding these emerging public health issues. Thus, it is critical to understand how healthcare professionals view this issue and are responding to it. This…

  5. Are Alternative Conceptions Dependent on Researchers' Methodology and Definition?: A Review of Empirical Studies Related to Concepts of Heat

    Science.gov (United States)

    Wong, Chee Leong; Chu, Hye-Eun; Yap, Kueh Chin

    2016-01-01

    Currently, there is no agreement among scientists and science educators on whether heat should be defined as a "process of energy transfer" or "form of energy." For example, students may conceive of heat as "molecular kinetic energy," but the interpretation of this alternative conception is dependent on educational…

  6. Sustainability indicators, alternative strategies and trade-offs in peasant agroecosystems : analysing 15 case studies from Latin America

    NARCIS (Netherlands)

    Astier, M.; Speelman, E.N.; López-Ridaura, S.; Masera, O.R.; Gonzalez-Esquivel, C.E.

    2011-01-01

    In view of the urgent need to improve agroecosystem sustainability, several efforts have been made to evaluate the effect of alternative strategies on key environmental and socioeconomic variables at the farm, community and regional levels. Most peasant farmers manage complex and diverse agroecosyst

  7. Advanced system demonstration for utilization of biomass as an energy source. Technical Appendix J: alternatives studies. Environmental report

    Energy Technology Data Exchange (ETDEWEB)

    McCollom, M. [ed.

    1979-01-01

    A comprehensive review of a wide range of alternatives to the proposed action, the commercial demonstration of an industrial cogenerating facility fired with wood fuels is provided. An extensive effort has been devoted to the evaluation of all reasonable alternatives to this project. A number of possible actions were also briefly considered, but, for various reasons, they were found not to be appropriate at present for a commercial-scale demonstration of an alternative energy source. The critical characteristics of the wood-fueled commercial demonstration project at Westbrook are considered to be: industrial cogeneration of power; the production of 510,000 pounds per hour of industrial process steam; the production of approximately twenty-five megawatts of electric generating capacity, some of which would be available to a public utility in southern Maine; and the consumption of 2,000 tons of wood fuel per day. Each of the alternatives examined in this appendix offers a different option for one or several of the characteristics of the project listed above. As a whole, the appendix describes the range of possible actions that the US Department of Energy and its contractors have considered.

  8. Use of black vulture (Coragyps atratus in complementary and alternative therapies for cancer in Colombia: A qualitative study

    Directory of Open Access Journals (Sweden)

    Sánchez-Pedraza Ricardo

    2012-05-01

    Full Text Available Abstract Background Although Coragyps atratus has been used as a traditional therapy for patients with cancer, the scientific literature does not contain enough information on how this therapy is used or the mechanisms that explain this therapeutic practice. Objectives To understand the methods of use and the reasons given by patients and caregivers for the use of Coragyps atratus in cancer treatment. Methods This study used a qualitative design based on twenty in-depth interviews of patients with cancer or caregivers of patients with the disease. The analysis of the text was based on an inductive thematic approach. Results Resistance to disease and immune enhancement are properties attributed to Coragyps atratus when used for cancer treatment. The most recommended method of use is fresh blood ingestion, and the associated mechanism of action is transfer of immune factors to the individual who consumes it. Conclusions Use of Coragyps atratus as a treatment for cancer is a popular alternative therapy in Colombia. More studies are needed to understand the clinical effects of this intervention in cancer patients. Spanish abstract Introducción Aunque Coragyps atratus se usa tradicionalmente como terapia para pacientes con cáncer, no existe suficiente información en la literatura científica sobre su forma de utilización ni sobre los mecanismos explicativos que subyacen a esta práctica terapéutica. Objetivos Conocer métodos de utilización y mecanismos explicativos dados por los pacientes y cuidadores de pacientes sobre el uso de Coragyps atratus en el tratamiento del cáncer. Materiales y métodos Diseño cualitativo basado en veinte entrevistas en profundidad de pacientes con cáncer o cuidadores de pacientes con esta enfermedad. Análisis de texto basado en enfoque temático inductivo. Resultados Al Coragyps atratus se le atribuyen propiedades de resistencia y fortalecimiento del sistema inmune de personas enfermas de cáncer. La forma de

  9. Use of black vulture (Coragyps atratus) in complementary and alternative therapies for cancer in Colombia: A qualitative study

    Science.gov (United States)

    2012-01-01

    Background Although Coragyps atratus has been used as a traditional therapy for patients with cancer, the scientific literature does not contain enough information on how this therapy is used or the mechanisms that explain this therapeutic practice. Objectives To understand the methods of use and the reasons given by patients and caregivers for the use of Coragyps atratus in cancer treatment. Methods This study used a qualitative design based on twenty in-depth interviews of patients with cancer or caregivers of patients with the disease. The analysis of the text was based on an inductive thematic approach. Results Resistance to disease and immune enhancement are properties attributed to Coragyps atratus when used for cancer treatment. The most recommended method of use is fresh blood ingestion, and the associated mechanism of action is transfer of immune factors to the individual who consumes it. Conclusions Use of Coragyps atratus as a treatment for cancer is a popular alternative therapy in Colombia. More studies are needed to understand the clinical effects of this intervention in cancer patients. Spanish abstract Introducción Aunque Coragyps atratus se usa tradicionalmente como terapia para pacientes con cáncer, no existe suficiente información en la literatura científica sobre su forma de utilización ni sobre los mecanismos explicativos que subyacen a esta práctica terapéutica. Objetivos Conocer métodos de utilización y mecanismos explicativos dados por los pacientes y cuidadores de pacientes sobre el uso de Coragyps atratus en el tratamiento del cáncer. Materiales y métodos Diseño cualitativo basado en veinte entrevistas en profundidad de pacientes con cáncer o cuidadores de pacientes con esta enfermedad. Análisis de texto basado en enfoque temático inductivo. Resultados Al Coragyps atratus se le atribuyen propiedades de resistencia y fortalecimiento del sistema inmune de personas enfermas de cáncer. La forma de utilización mas común es la

  10. The Gillings Sampler – An Electrostatic Air Sampler as an Alternative Method for Aerosol In Vitro Exposure Studies

    Science.gov (United States)

    Zavala, Jose; Lichtveld, Kim; Ebersviller, Seth; Carson, Johnny L.; Walters, Glenn W.; Jaspers, Ilona; Jeffries, Harvey E.; Sexton, Kenneth G.; Vizuete, William

    2014-01-01

    There is growing interest in studying the toxicity and health risk of exposure to multi-pollutant mixtures found in ambient air, and the U.S. Environmental Protection Agency (EPA) is moving towards setting standards for these types of mixtures. Additionally, the Health Effects Institute's strategic plan aims to develop and apply next-generation multi-pollutant approaches to understanding the health effects of air pollutants. There's increasing concern that conventional in vitro exposure methods are not adequate to meet EPA's strategic plan to demonstrate a direct link between air pollution and health effects. To meet the demand for new in vitro technology that better represents direct air-to-cell inhalation exposures, a new system that exposes cells at the air-liquid interface was developed. This new system, named the Gillings Sampler, is a modified two-stage electrostatic precipitator that provides a viable environment for cultured cells. Polystyrene latex spheres were used to determine deposition efficiencies (38-45%), while microscopy and imaging techniques were used to confirm uniform particle deposition. Negative control A549 cell exposures indicated the sampler can be operated for up to 4 hours without inducing any significant toxic effects on cells, as measured by lactate dehydrogenase (LDH) and interleukin-8 (IL-8). A novel positive aerosol control exposure method, consisting of a p-tolualdehyde (TOLALD) impregnated mineral oil aerosol (MOA), was developed to test this system. Exposures to the toxic MOA at a 1 ng/cm2 dose of TOLALD yielded a reproducible 1.4 and 2 fold increase in LDH and IL-8 mRNA levels over controls. This new system is intended to be used as an alternative research tool for aerosol in vitro exposure studies. While further testing and optimization is still required to produce a “commercially ready” system, it serves as a stepping-stone in the development of cost-effective in vitro technology that can be made accessible to researchers

  11. An Exploratory Study to Develop an Alternative Model of Public Library Management Using the Institute of Museum and Library Services' Public Library Statistics

    Science.gov (United States)

    Kim, Giyeong; Yu, So Young

    2011-01-01

    In this explorative study, we first investigate current use of public library statistics in public library management to identify a governing framework and then carefully suggest an alternative framework with income as a goal for sustainability. The meaning of income in terms of management is also discussed. Within this framework, we conduct a…

  12. Alternative Splice in Alternative Lice.

    Science.gov (United States)

    Tovar-Corona, Jaime M; Castillo-Morales, Atahualpa; Chen, Lu; Olds, Brett P; Clark, John M; Reynolds, Stuart E; Pittendrigh, Barry R; Feil, Edward J; Urrutia, Araxi O

    2015-10-01

    Genomic and transcriptomics analyses have revealed human head and body lice to be almost genetically identical; although con-specific, they nevertheless occupy distinct ecological niches and have differing feeding patterns. Most importantly, while head lice are not known to be vector competent, body lice can transmit three serious bacterial diseases; epidemictyphus, trench fever, and relapsing fever. In order to gain insights into the molecular bases for these differences, we analyzed alternative splicing (AS) using next-generation sequencing data for one strain of head lice and one strain of body lice. We identified a total of 3,598 AS events which were head or body lice specific. Exon skipping AS events were overrepresented among both head and body lice, whereas intron retention events were underrepresented in both. However, both the enrichment of exon skipping and the underrepresentation of intron retention are significantly stronger in body lice compared with head lice. Genes containing body louse-specific AS events were found to be significantly enriched for functions associated with development of the nervous system, salivary gland, trachea, and ovarian follicle cells, as well as regulation of transcription. In contrast, no functional categories were overrepresented among genes with head louse-specific AS events. Together, our results constitute the first evidence for transcript pool differences in head and body lice, providing insights into molecular adaptations that enabled human lice to adapt to clothing, and representing a powerful illustration of the pivotal role AS can play in functional adaptation. PMID:26169943

  13. Complementary alternative medicine use among patients with type 2 diabetes mellitus in the primary care setting: a cross-sectional study in Malaysia

    OpenAIRE

    Ching, Siew Mooi; Zakaria, Zainul Amiruddin; Paimin, Fuziah; Jalalian, Mehrdad

    2013-01-01

    Background Limited study on the use of complementary alternative medicine (CAM) among patients with diabetes mellitus (DM), particularly in primary -care settings. This study seeks to understand the prevalence, types, expenditures, attitudes, beliefs, and perceptions of CAM use among patients with DM visiting outpatient primary care clinics. Methods This is a descriptive, cross-sectional study of 240 diabetic patients. CAM is defined as a group of diverse medical and healthcare systems, pract...

  14. Looking for an Alternative.

    Science.gov (United States)

    Kennedy, Jack

    1999-01-01

    Argues that high school newspapers might do well to create stronger ties with alternative weeklies. Discusses issues of niche marketing, alternative content, and alternative presentation. Notes that high school papers could learn a lot from alternative newspapers. (SR)

  15. Experimental Study and Numerical Simulation of the Casting-Forging Complex Near Net Forming of Alternator Claw-pole

    Institute of Scientific and Technical Information of China (English)

    J.L.Song; D.J.Hu; Q.C.Wang; H.Q.Chen; H.G.Guo

    2004-01-01

    As a newly developed precision technology, casting-forging complex near net forming process is utilized to produce complex components with a short lead time, low cost and high precision, thus to accelerate the response speed of the market and enhance the competitive power of products. In this paper, the casting-forging complex near net forming process of alternator claw pole was developed and investigated with a combination of experimental and numerical simulation method. Qualified near net workpiece was manufactured, mechanical parameter and relative field information during the forming process was also obtained. While the alternator claw-pole is processed with this technology, the forming force is small, the process is short and the quality of forgings is perfect. Therefore, the complex casting-forging near net forming process of claw-pole is an energy and material saving technology, which will have a vast developing and application prospect in the future.

  16. Study of an anaerobic - aerobic reactor of alternate phases for the removal of organic matter and nutritious, nitrogen and phosphorus

    International Nuclear Information System (INIS)

    In this article the results of the behavior from a reactor to laboratory scale with half fixed and anaerobic-aerobic alternate phases, for the organic and nutritious simultaneous removal of matter is presented. The laboratory assembly it makes with two reactors, of 2,2 l (litre) of capacity each one, connected in series, low continuous feeding, and the control of a system of solenoids valves that it allowed to automatically program of anaerobic-aerobic alternate phases in each reactor. Under this outline efficiency was obtained in removal of COD (Chemical Oxygen Demand) between 88 and 92%, of phosphorus of 87% and nitrogen of 77 to 60%, and lower volumetric loads between 2,5 and 0,38 g COD/l-d. The process generates a low sludge production, presenting economic advantages in front of aerobic traditional systems and to the removal technologies of nutritious

  17. A virtual repository approach to clinical and utilization studies: application in mammography as alternative to a national database.

    OpenAIRE

    Ohno-Machado, L.; Boxwala, A. A.; Ehresman, J.; Smith, D N; Greenes, R. A.

    1997-01-01

    A national mammography database was proposed, based on a centralized architecture for collecting, monitoring, and auditing mammography data. We have developed an alternative architecture relying on Internet-based distributed queries to heterogeneous databases. This architecture creates a "virtual repository", or a federated database which is constructed dynamically, for each query and makes use of data available in legacy systems. It allows the construction of custom-tailored databases at ind...

  18. Feasibility Study for Preparation and Use of Glass Grains as an Alternative to Glass Nodules for Vitrification of Nuclear Waste

    International Nuclear Information System (INIS)

    High level nuclear liquid waste (HLW) is immobilized using borosilicate glass matrix. Presently joule heated ceramic melter is being employed for vitrification of HLW in India. Preformed nodules of base glass are fed to melter along with liquid waste in predetermined ratio. In order to reduce the cost incurred for production of glass nodules of base glass, an alternative option of using glass grains was evaluated for its preparation and its suitability for the melter operation. (author)

  19. The development of an in vitro model for studying mechanisms of nephrotoxicity as an alternative for animal experiments.

    OpenAIRE

    Mertens, J.J.W.M.

    1991-01-01

    SUMMARYPresently in our society animal tests still form the main starting point for the assessment of the possible risks of chemicals with regard to human and animal health. For scientific. economic, and ethical reasons. attempts are undertaken continuously to develop cell models as alternatives to animal testing. However, the predictive value of in vitro test systems is often limited due to the unawareness about the mechanisms of toxicity and the complexity of organisms. As a consequence, a ...

  20. Palm oil production in Peruvian Amazon Basin. A case study of current effects and emerging localized alternatives in Loreto district

    OpenAIRE

    Jensen, Charlotte Bratberget

    2015-01-01

    An analysis of palm oil production in the Peruvian Amazon basin was carried out in a systemic way, as part of a whole, with its complexities. With an agroecological perspective, the social, ecological and economic effects of this production are discussed. Additionally, alternatives that could better fulfil the necessities of farmers were explored. The oil palm, Elaeis guineensis, originally from West Africa, is a common plant in an enormous industry that is extensive in South East Asia, ma...

  1. Estudo da durabilidade de argamassas alternativas contendo resíduos Durability study of alternative mortars containing wastes

    Directory of Open Access Journals (Sweden)

    J. Farias Filho

    2011-12-01

    study the durability of the alternative mortar incorporated with residues from civil construction and from granite industry. To quantify the durability of the studied materials, it was made test of natural and accelerated weathering through wetting and drying cycles. The materials were submitted to conditions that simulated their use to evaluate their degradation. In the studies of durability of the mortar elevation, percentages of substitutions of lime by recycling residue were used. The amount changed from 30% to 50%. The natural weathering cause a compromise in the durability of the material after 60 days with a decrease in the mechanical behavior and the best results occur to the sample with 30% and 50% of residue. In the accelerated weathering, the results show indicate the formation of calcium and potassium aluminosilicates that can give an increase in the mechanical behavior, however, it was not observed a compromise in the material durability.

  2. Alternative Green Solvents Project

    Science.gov (United States)

    Maloney, Phillip R.

    2012-01-01

    Necessary for safe and proper functioning of equipment. Mainly halogenated solvents. Tetrachloride, Trichloroethylene (TCE), CFC-113. No longer used due to regulatory/safety concerns. Precision Cleaning at KSC: Small % of total parts. Used for liquid oxygen (LOX) systems. Dual solvent process. Vertrel MCA (decafluoropentane (DFP) and trons-dichloroethylene) HFE-7100. DFP has long term environmental concerns. Project Goals: a) Identify potential replacements. b) 22 wet chemical processes. c) 3 alternative processes. d) Develop test procedures. e) Contamination and cleaning. f) Analysis. g) Use results to recommend alternative processes. Conclusions: a) No alternative matched Vertrel in this study. b) No clear second place solvent. c) Hydrocarbons- easy; Fluorinated greases- difficult. d) Fluorinated component may be needed in replacement solvent. e) Process may need to make up for shortcoming of the solvent. f) Plasma and SCC02 warrant further testing.

  3. Alternative Evaluation Study: Methods to Mitigate/Accommodate Subsidence for the Radioactive Waste Management Sites at the Nevada Test Site, Nye County Nevada, with Special Focus on Disposal Cell U-3ax/bl

    Energy Technology Data Exchange (ETDEWEB)

    Barker, L.

    1997-09-01

    An Alternative Evaluation Study is a type of systematic approach to problem identification and solution. An Alternative Evaluation Study was convened August 12-15, 1997, for the purpose of making recommendations concerning closure of Disposal Cell U-3ax/bl and other disposal cells and mitigation/accommodation of waste subsidence at the Radioactive Waste Management Sites at the Nevada Test Site. This report includes results of the Alternative Evaluation Study and specific recommendations.

  4. On sulfur core level binding energies in thiol self-assembly and alternative adsorption sites: An experimental and theoretical study

    International Nuclear Information System (INIS)

    Characteristic core level binding energies (CLBEs) are regularly used to infer the modes of molecular adsorption: orientation, organization, and dissociation processes. Here, we focus on a largely debated situation regarding CLBEs in the case of chalcogen atom bearing molecules. For a thiol, this concerns the case when the CLBE of a thiolate sulfur at an adsorption site can be interpreted alternatively as due to atomic adsorption of a S atom, resulting from dissociation. Results of an investigation of the characteristics of thiol self-assembled monolayers (SAMs) obtained by vacuum evaporative adsorption are presented along with core level binding energy calculations. Thiol ended SAMs of 1,4-benzenedimethanethiol (BDMT) obtained by evaporation on Au display an unconventional CLBE structure at about 161.25 eV, which is close to a known CLBE of a S atom on Au. Adsorption and CLBE calculations for sulfur atoms and BDMT molecules are reported and allow delineating trends as a function of chemisorption on hollow, bridge, and atop sites and including the presence of adatoms. These calculations suggest that the 161.25 eV peak is due to an alternative adsorption site, which could be associated to an atop configuration. Therefore, this may be an alternative interpretation, different from the one involving the adsorption of atomic sulfur resulting from the dissociation process of the S–C bond. Calculated differences in S(2p) CLBEs for free BDMT molecules, SH group sulfur on top of the SAM, and disulfide are also reported to clarify possible errors in assignments

  5. On sulfur core level binding energies in thiol self-assembly and alternative adsorption sites: An experimental and theoretical study

    Energy Technology Data Exchange (ETDEWEB)

    Jia, Juanjuan [Institut des Sciences Moléculaires d’Orsay, Université-Paris Sud, 91405 Orsay (France); CNRS, UMR 8214, Institut des Sciences Moléculaires d’Orsay, Orsay ISMO, Bâtiment 351, Université Paris Sud, 91405 Orsay (France); Kara, Abdelkader, E-mail: abdelkader.kara@ucf.edu, E-mail: vladimir.esaulov@u-psud.fr [Department of Physics, University of Central Florida, Orlando, Florida 32816 (United States); Pasquali, Luca [Dipartimento di Ingegneria “E. Ferrari,” Università di Modena e Reggio Emilia, Via Vignolese 905, 41125 Modena (Italy); IOM-CNR, s.s. 14, Km. 163.5 in AREA Science Park, 34149 Basovizza, Trieste (Italy); Department of Physics, University of Johannesburg, P.O. Box 524, Auckland Park 2006 (South Africa); Bendounan, Azzedine; Sirotti, Fausto [Synchrotron SOLEIL, L’Orme des Merisiers, Saint-Aubin, BP 48, F-91192 Gif-sur-Yvette Cedex (France); Esaulov, Vladimir A., E-mail: abdelkader.kara@ucf.edu, E-mail: vladimir.esaulov@u-psud.fr [Institut des Sciences Moléculaires d’Orsay, Université-Paris Sud, 91405 Orsay (France); CNRS, UMR 8214, Institut des Sciences Moléculaires d’Orsay, Orsay ISMO, Bâtiment 351, Université Paris Sud, 91405 Orsay (France); IOM-CNR, s.s. 14, Km. 163.5 in AREA Science Park, 34149 Basovizza, Trieste (Italy)

    2015-09-14

    Characteristic core level binding energies (CLBEs) are regularly used to infer the modes of molecular adsorption: orientation, organization, and dissociation processes. Here, we focus on a largely debated situation regarding CLBEs in the case of chalcogen atom bearing molecules. For a thiol, this concerns the case when the CLBE of a thiolate sulfur at an adsorption site can be interpreted alternatively as due to atomic adsorption of a S atom, resulting from dissociation. Results of an investigation of the characteristics of thiol self-assembled monolayers (SAMs) obtained by vacuum evaporative adsorption are presented along with core level binding energy calculations. Thiol ended SAMs of 1,4-benzenedimethanethiol (BDMT) obtained by evaporation on Au display an unconventional CLBE structure at about 161.25 eV, which is close to a known CLBE of a S atom on Au. Adsorption and CLBE calculations for sulfur atoms and BDMT molecules are reported and allow delineating trends as a function of chemisorption on hollow, bridge, and atop sites and including the presence of adatoms. These calculations suggest that the 161.25 eV peak is due to an alternative adsorption site, which could be associated to an atop configuration. Therefore, this may be an alternative interpretation, different from the one involving the adsorption of atomic sulfur resulting from the dissociation process of the S–C bond. Calculated differences in S(2p) CLBEs for free BDMT molecules, SH group sulfur on top of the SAM, and disulfide are also reported to clarify possible errors in assignments.

  6. Benefits and Costs of Aggressive Energy Efficiency Programs and the Impacts of Alternative Sources of Funding: Case Study of Massachusetts

    Energy Technology Data Exchange (ETDEWEB)

    Cappers, Peter; Satchwell, Andrew; Goldman, Charles; Schlegel, Jeff

    2010-08-06

    Increased interest by state (and federal) policymakers and regulatory agencies in pursuing aggressive energy efficiency efforts could deliver significant utility bill savings for customers while having long-term implications for ratepayers (e.g. potential rate impacts). Equity and distributional concerns associated with the authorized recovery of energy efficiency program costs may necessitate the pursuit of alternative program funding approaches. In 2008, Massachusetts passed the Green Communities Act which directed its energy efficiency (EE) program administrators to obtain all cost-effective EE resources. This goal has translated into achieving annual electric energy savings equivalent to a 2.4% reduction in retail sales from energy efficiency programs in 2012. Representatives of electricity consumer groups supported the new portfolio of EE programs (and the projected bill savings) but raised concerns about the potential rate impacts associated with achieving such aggressive EE goals, leading policymakers to seek out alternative funding sources which can potentially mitigate these effects. Utility administrators have also raised concerns about under-recovery of fixed costs when aggressive energy efficiency programs are pursued and have proposed ratemaking policies (e.g. decoupling) and business models that better align the utility's financial interests with the state's energy efficiency public policy goals. Quantifying these concerns and identifying ways they can be addressed are crucial steps in gaining the support of major stakeholder groups - lessons that can apply to other states looking to significantly increase savings targets that can be achieved from their own ratepayer-funded energy efficiency programs. We use a pro-forma utility financial model to quantify the bill and rate impacts on electricity customers when very aggressive annual energy efficiency savings goals ({approx}2.4%) are achieved over the long-term and also assess the impact of

  7. A feasibility study of using Biomethane as an alternative fuel for taxis in the Reykjavík capital area

    OpenAIRE

    Hannes Arnórsson

    2011-01-01

    Price of gasoline at the dispenser in Iceland has never been higher than today. This paper investigates the economic feasibility of using biomethane as an alternative fuel for the taxi fleet in the Reykjavík capital area. Cases of different groups of taxis were set up on the basis of existing data of the fleet and the financial feasibility evaluated. The cases were divided into separate groups based on the emission classes and various scenarios and sensitivity analysis applied. The research l...

  8. The analysis of covariance and alternatives statistical methods for experiments, quasi-experiments, and single-case studies

    CERN Document Server

    Huitema, Bradley

    2011-01-01

    A complete guide to cutting-edge techniques and best practices for applying covariance analysis methods The Second Edition of Analysis of Covariance and Alternatives sheds new light on its topic, offering in-depth discussions of underlying assumptions, comprehensive interpretations of results, and comparisons of distinct approaches. The book has been extensively revised and updated to feature an in-depth review of prerequisites and the latest developments in the field. The author begins with a discussion of essential topics relating to experimental design and analysis

  9. A virtual repository approach to clinical and utilization studies: application in mammography as alternative to a national database.

    Science.gov (United States)

    Ohno-Machado, L; Boxwala, A A; Ehresman, J; Smith, D N; Greenes, R A

    1997-01-01

    A national mammography database was proposed, based on a centralized architecture for collecting, monitoring, and auditing mammography data. We have developed an alternative architecture relying on Internet-based distributed queries to heterogeneous databases. This architecture creates a "virtual repository", or a federated database which is constructed dynamically, for each query and makes use of data available in legacy systems. It allows the construction of custom-tailored databases at individual sites that can serve the dual purposes of providing data (a) to researchers through a common mammography repository and (b) to clinicians and administrators at participating institutions. We implemented this architecture in a prototype system at the Brigham and Women's Hospital to show its feasibility. Common queries are translated dynamically into database-specific queries, and the results are aggregated for immediate display or download by the user. Data reside in two different databases and consist of structured mammography reports, coded per BIRADS Standardized Mammography Lexicon, as well as pathology results. We prospectively collected data on 213 patients, and showed that our system can perform distributed queries effectively. We also implemented graphical exploratory analysis tools to allow visualization of results. Our findings indicate that the architecture is not only feasible, but also flexible and scaleable, constituting a good alternative to a national mammography database. PMID:9357650

  10. Widening the Scope of Scenario Planning in Small Communities: a Case Study Use of an Alternative Method

    Directory of Open Access Journals (Sweden)

    Annelise Godber

    2011-03-01

    Full Text Available Scenario planning can be invaluable for empowerment and learning in resource dependent communities. Pre-existing scenario planning methods call for collaboration between community members, but when cultural norms prevented men, women, and youth from coming together in the community of Ukupseni in Panama, the authors and community sought to devise an alternative method. The research objectives were twofold. First, to develop an alternative scenario planning method that would facilitate learning among decision makers about community needs and perspectives, and second, to explore ways to direct desired futures. Instead of forecasting through community-wide collaboration and backcasting with the creation of one vision through consensus, forecasting used individual interviews to create scenarios and backcasting was conducted separately with each of the six community groups (older women, young women with children, young women without children, young men, older men including fishermen and lobster-catchers, and individuals with formal education resulting in several visions. To unify the results, we created an organizational matrix that allowed the visions of different community groups to be compared. The organizational matrix allowed decision makers to observe that women and youth, the most marginalized members of the community, had convergent visions that were very different from men whose perspectives and knowledge are more often included in decision making.

  11. A Study of Pollutant Formation from the Lean Premixed Combustion of Gaseous Fuel Alternatives to Natural Gas

    Science.gov (United States)

    Fackler, Keith Boyd, Jr.

    The goal of this research is to identify how nitrogen oxide (NO x) emissions and flame stability (blowout) are impacted by the use of fuels that are alternatives to typical pipeline natural gas. The research focuses on lean, premixed combustors that are typically used in state-of-the-art natural gas fueled systems. An idealized laboratory lean premixed combustor, specifically the jet-stirred reactor, is used for experimental data. A series of models, including those featuring detailed fluid dynamics and those focusing on detailed chemistry, are used to interpret the data and understand the underlying chemical kinetic reasons for differences in emissions between the various fuel blends. An ultimate goal is to use these data and interpretive tools to develop a way to predict the emission and stability impacts of changing fuels within practical combustors. All experimental results are obtained from a high intensity, single-jet stirred reactor (JSR). Five fuel categories are studied: (1) pure H 2, (2) process and refinery gas, including combinations of H2, CH4, C2H6, and C3H8, (3) oxygen blown gasified coal/petcoke composed of H2, CO, and CO2, (4) landfill and digester gas composed of CH4, CO2, and N2, and (5) liquified natural gas (LNG)/shale/associated gases composed of CH4, C2H6, and C3 H8. NOx measurements are taken at a nominal combustion temperature of 1800 K, atmospheric pressure, and a reactor residence time of 3 ms. This is done to focus the results on differences caused by fuel chemistry by comparing all fuels at a common temperature, pressure, and residence time. This is one of the few studies in the literature that attempts to remove these effects when studying fuels varying in composition. Additionally, the effects of changing temperature and residence time are investigated for selected fuels. At the nominal temperature and residence time, the experimental and modeling results show the following trends for NOx emissions as a function of fuel type: 1.) NOx

  12. Inter‑laboratory study of human in vitro toxicogenomics‑based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective

    OpenAIRE

    Herwig, Ralf; GMUENDER Hans; Corvi, Raffaella; Bloch, K; CASTELL Jose; Ceelen, Liesbeth; Chesne, Christopher; DOKTOROVA Tatyana; Jennen, Danyel G.J.; Jennings, Paul; Limonciel, Alice; LOCK Edward; Mcmorrow, Tara; PHRAKONKHAM Pascal; Radford, R

    2015-01-01

    The assessment of the carcinogenic potential of chemicals with alternative, human-based in vitro systems has become a major goal of toxicogenomics. The central read-out of these assays is the transcriptome and the induced expression changes upon chemical exposure. While many studies exist that describe the transcriptomic responses of such systems, reports on robustness and reproducibility when testing the systems independently in different laboratories are uncommon. Furthermore, there is limi...

  13. The potential of complementary and alternative medicine in promoting well-being and critical health literacy: a prospective, observational study of shiatsu

    OpenAIRE

    Long Andrew F

    2009-01-01

    Abstract Background The potential contribution of complementary and alternative medicine (CAM) modalities to promote and support critical health literacy has not received substantial attention within either the health promotion or the CAM literature. This paper explores the potential of one CAM modality, shiatsu, in promoting well-being and critical health literacy. Methods Data are drawn from a longitudinal, 6 months observational, pragmatic study of the effects and experience of shiatsu wit...

  14. Studies on teff (Eragrostis tef) malt as alternative raw material for lactic acid fermented gluten-free beverages

    OpenAIRE

    Gebremariam, Mekonnen Melaku

    2015-01-01

    This project was designed to study influences of kilning conditions on quality attributes of teff malt, and thermal stabilities of its amylolytic enzymes, and develop processing conditions to utilize it as alternative raw material for gluten-free beverage. To this end, optimal kilning and mashing conditions were developed, and finally, an optimal fermentation condition yielding a beverage with sufficiently low pH to suppress growth of food spoilage microorganisms and acceptable sensory qualit...

  15. Novel, low-cost alternative technologies to tackle practical, industrial conundrums – a case study of batteries

    Directory of Open Access Journals (Sweden)

    Chan Victor K. Y.

    2016-01-01

    Full Text Available Whereas batteries in comparison with most other means of energy storage are more environmentally friendly and economical in their operation, they are beset by low energy replenishment rates, low energy storage density, high capital cost of themselves, and high capital cost of energy replenishment infrastructures. Mainly based on ergonomics, this paper proposes a novel, low-cost alternative technology to practically and industrially make these weaknesses irrelevant to some extent without calling for revolutionary technological breakthroughs in material science, batteries’ microstructures, or battery manufacturing technologies. The technology takes advantage of modularization of battery systems, prioritization of charging and discharging of battery module(s according to ease of unloading and/or loading the battery module(s and/or ease of loading replacement battery module(s of the battery module(s.

  16. Energy potential and alternative usages of biogas and sludge from UASB reactors: case study of the Laboreaux wastewater treatment plant.

    Science.gov (United States)

    Rosa, A P; Conesa, J A; Fullana, A; Melo, G C B; Borges, J M; Chernicharo, C A L

    2016-01-01

    This work assessed the energy potential and alternative usages of biogas and sludge generated in upflow anaerobic sludge blanket reactors at the Laboreaux sewage treatment plant (STP), Brazil. Two scenarios were considered: (i) priority use of biogas for the thermal drying of dehydrated sludge and the use of the excess biogas for electricity generation in an ICE (internal combustion engine); and (ii) priority use of biogas for electricity generation and the use of the heat of the engine exhaust gases for the thermal drying of the sludge. Scenario 1 showed that the electricity generated is able to supply 22.2% of the STP power demand, but the thermal drying process enables a greater reduction or even elimination of the final volume of sludge to be disposed. In Scenario 2, the electricity generated is able to supply 57.6% of the STP power demand; however, the heat in the exhaust gases is not enough to dry the total amount of dehydrated sludge.

  17. A Pilot-scale Study on Coal Gasification Wastewater Reclamation Using Pretreatment Alternatives Combined with Ultrafiltration and Reverse Osmosis

    Institute of Scientific and Technical Information of China (English)

    Qian Zhao; Hongjun Han; Fang Fang; Peng Xu; Kun Li; Dexin Wang

    2015-01-01

    Aims to investigate the performance of the pilot⁃scale reclamation plant for coal gasification wastewater ( CGW) using ultrafiltration and reverse osmosis with appropriate pretreatment alternatives, different pre⁃treatment alternatives⁃coagulation, adsorption, and ozonation methods were employed to treat the secondary effluent of coal gasification wastewater ( SECGW ) in a pilot⁃scale pressurized membrane system. The performance was compared to choose the most suitable pre⁃treatment alternative for the SECGW reclamation. Ozone reaction achieved highest COD removal efficiency (79.6%-91.0%), resulting in the stable normalized parameters of the subsequent ultrafiltration and reverse osmoses. In contrast, the coagulation and adsorption processes achieved only 32. 8%-45. 7% and 53. 1%-64. 6% decreases in COD, respectively. The residual organic pollutants in the reverse osmosis feed water led to an increase in normalized pressure drop and a decrease in normalized permeability ( or membrane transference coefficient) . The hydrophobic fraction was the main constituent ( approx. 70% of DOC ) in pretreated SECGW, and the hydrophobic⁃neutral fraction contributed mostly to the UV absorbance ( 53%) . Fluorescence excitation emission matrices revealed that ozonation removed most of the hydrophobic and aromatic proteins such as tyrosine and tryptophan which dominated in raw wastewater. The recalcitrant compounds such as phenolic compounds, heterocyclic compounds, especially long⁃chain hydrocarbons, which were easily attached to the membrane surface and contributed to organic fouling, could be oxidized and mineralized by ozone. Among the three pretreatments, ozonation showed highest removal efficiencies of hydrophobic and aromatic proteins, therefore resulting in highest normalized permeability.

  18. An international multicenter study evaluating the impact of an alternative biochemical failure definition on the judgment of prostate cancer risk

    International Nuclear Information System (INIS)

    Purpose: To evaluate the impact of an alternative biochemical failure (bF) definition on the performance of existing plus de novo prognostic models. Methods and Materials: The outcomes data of 1,458 Australian and 703 Canadian men treated with external-beam radiation monotherapy between 1993 and 1997 were analyzed using a lowest prostate-specific antigen (PSA) level to date plus 2 ng/mL (L + 2) bF definition. Two existing prognostic models were scrutinized using discrimination (Somers Dxy [SDxy]) and calibration indices. Alternative prognostic models were also created using recursive partitioning analysis (RPA) and multivariate nomogram methods for comparison. Results: Discrimination of bF was improved using the L + 2 definition compared with the American Society for Therapeutic Radiology and Oncology (ASTRO) definition using both the three-level risk model (SDxy 0.30 and 0.22, respectively) or the nomogram (SDxy 0.35 and 0.27, respectively). Both existing prognostic models showed only modest calibration accuracy. Using RPA, five distinct risk groups were identified based primarily on Gleason score (GS) and all subsequent divisions based on PSA. All GS 7-10 tumors were intermediate or high risk. This model and the developed nomogram showed improved discrimination over the existing models as well as accurate calibration against the Canadian data, apart from the 30-50% failure region. Conclusions: The L + 2 definition of bF provides improved capacity for discrimination of failure risk. New prognostic models based on this endpoint have overall statistical performance superior to those based on the ASTRO consensus definition but continue to have unreliable discrimination in the intermediate-risk region

  19. EASI—enrichment of alternatively spliced isoforms

    OpenAIRE

    Julian P Venables; Burn, John

    2006-01-01

    Alternative splicing produces more than one protein from the majority of genes and the rarer forms can have dominant functions. Instability of alternative transcripts can also hinder the study of regulation of gene expression by alternative splicing. To investigate the true extent of alternative splicing we have developed a simple method of enriching alternatively spliced isoforms (EASI) from PCRs using beads charged with Thermus aquaticus single-stranded DNA-binding protein (T.Aq ssb). This ...

  20. Energy potential and alternative usages of biogas and sludge from UASB reactors: case study of the Laboreaux wastewater treatment plant.

    Science.gov (United States)

    Rosa, A P; Conesa, J A; Fullana, A; Melo, G C B; Borges, J M; Chernicharo, C A L

    2016-01-01

    This work assessed the energy potential and alternative usages of biogas and sludge generated in upflow anaerobic sludge blanket reactors at the Laboreaux sewage treatment plant (STP), Brazil. Two scenarios were considered: (i) priority use of biogas for the thermal drying of dehydrated sludge and the use of the excess biogas for electricity generation in an ICE (internal combustion engine); and (ii) priority use of biogas for electricity generation and the use of the heat of the engine exhaust gases for the thermal drying of the sludge. Scenario 1 showed that the electricity generated is able to supply 22.2% of the STP power demand, but the thermal drying process enables a greater reduction or even elimination of the final volume of sludge to be disposed. In Scenario 2, the electricity generated is able to supply 57.6% of the STP power demand; however, the heat in the exhaust gases is not enough to dry the total amount of dehydrated sludge. PMID:27054741

  1. The Unsuccessful Poverty Reduction Strategies in Indonesia and the Alternatives Solutions (The Study on BLT and Jamkesmas

    Directory of Open Access Journals (Sweden)

    Dewi Iriani

    2014-08-01

    Full Text Available Indonesia as the 16th largest economy in the world, the 4th in Asia-after China, Japan and India as well as Southeast Asia’s largest-has the potential to be the seventh biggest by 2030, due to the increasing economic. Indonesia also has many potential natural resources that can be utilized to support development in order to increase the nation welfare. However, the number of poor people still has not been significantly reduced, reaching 28.07 million or 11.37% of the total population in 2013. The Government has tried to reduce poverty with some programs such as BLT (Bantuan Langsung Tunai/Direct Cash Assistance and Jamkesmas (Jaminan Kesehatan Masyarakat/ Community Health Protection Scheme. However, the programs are considered not effective and do not make poor people become financially independent. Ironically, in inadequate evaluation, the Government continues to runs the programs. By using a qualitative approach, researchers will provide policy alternatives that can be implemented by Government.

  2. Adaptive Alternating Minimization Algorithms

    CERN Document Server

    Niesen, Urs; Wornell, Gregory

    2007-01-01

    The classical alternating minimization (or projection) algorithm has been successful in the context of solving optimization problems over two variables or equivalently of finding a point in the intersection of two sets. The iterative nature and simplicity of the algorithm has led to its application to many areas such as signal processing, information theory, control, and finance. A general set of sufficient conditions for the convergence and correctness of the algorithm is quite well-known when the underlying problem parameters are fixed. In many practical situations, however, the underlying problem parameters are changing over time, and the use of an adaptive algorithm is more appropriate. In this paper, we study such an adaptive version of the alternating minimization algorithm. As a main result of this paper, we provide a general set of sufficient conditions for the convergence and correctness of the adaptive algorithm. Perhaps surprisingly, these conditions seem to be the minimal ones one would expect in ...

  3. [Alternatives to animal testing].

    Science.gov (United States)

    Fabre, Isabelle

    2009-11-01

    The use of alternative methods to animal testing are an integral part of the 3Rs concept (refine, reduce, replace) defined by Russel & Burch in 1959. These approaches include in silico methods (databases and computer models), in vitro physicochemical analysis, biological methods using bacteria or isolated cells, reconstructed enzyme systems, and reconstructed tissues. Emerging "omic" methods used in integrated approaches further help to reduce animal use, while stem cells offer promising approaches to toxicologic and pathophysiologic studies, along with organotypic cultures and bio-artificial organs. Only a few alternative methods can so far be used in stand-alone tests as substitutes for animal testing. The best way to use these methods is to integrate them in tiered testing strategies (ITS), in which animals are only used as a last resort. PMID:20669543

  4. [Femoral nerve block as pain relief in hip fracture. A good alternative in perioperative treatment proved by a prospective study].

    Science.gov (United States)

    Kullenberg, Björn; Ysberg, Benita; Heilman, Martin; Resch, Sylvia

    2004-06-10

    Almost 25% of all patients with hip fracture experience temporary confusion pre- and directly postoperatively due to trauma, advanced age, transport between units, and the use of analgesics, 35-50% of the patients suffer temporary or chronic decubitus. Analgesics often lead to nausea. A femoral nerve block can interrupt sensory impulses from the hip joint and provide complete pain relief without affecting the CNS, thus making preoperative care easier and postoperative rehabilitation can be started earlier. 80 consecutive patients with hip fracture were randomized to femoral nerve block or pharmacological treatment only. Paracetamol and tramadol were the standard analgesics used. All patients were followed up with regard to pain, duration of the block, number of analgesics doses, temporary confusion and time for postoperative mobilization. Pain was estimated by the patients using the visual analogue scale (VAS). A nerve block was performed to block the femoral nerve, the lateral femoral cutaneous nerve and the obturator nerve with 30 ml of ropivacaine 7.5 mg/ml. Mental status was evaluated with Pfeiffer-test. All patients experienced relatively intense pain on admission with an average VAS of 6. After nerve block the VAS was 2. Pain relief was the same in the control group. Pain relief was sustained for 15 hours. The time for mobilization after surgery was significantly lower, 23 hours compared to 36 for the control group. There was a lower number of patients temporarily confused in the block group compared to the control group, however no significant differences were seen. Femoral nerve block provides adequate pain relief, equivalent to pharmacological treatment in most patients. The time for postoperative mobilization was shorter and less temporary confusion was seen. There were no complications in this group, making nerve block a good alternative to traditional pharmacological preoperative treatment for patients with hip fractures. PMID:15282985

  5. A comparative study on the alternating mesophilic and thermophilic two-stage anaerobic digestion of food waste.

    Science.gov (United States)

    Ventura, Jey-R Sabado; Lee, Jehoon; Jahng, Deokjin

    2014-06-01

    An alternating mesophilic and thermophilic two stage anaerobic digestion (AD) process was conducted. The temperature of the acidogenic (A) and methanogenic (M) reactors was controlled as follows: System 1 (S1) mesophilic A-mesophilic M; (S2) mesophilic A-thermophilic M; and (S3) thermophilic A-mesophilic M. Initially, the AD reactor was acclimatized and inoculated with digester sludge. Food waste was added with the soluble chemical oxygen demand (SCOD) concentrations of 41.4-47.0 g/L and volatile fatty acids of 2.0-3.2 g/L. Based on the results, the highest total chemical oxygen demand removal (86.6%) was recorded in S2 while S3 exhibited the highest SCOD removal (96.6%). Comparing S1 with S2, total solids removal increased by 0.5%; S3 on the other hand decreased by 0.1 % as compared to S1. However, volatile solids (VS) removal in S1, S2, and S3 was 78.5%, 81.7%, and 79.2%, respectively. S2 also exhibited the highest CH4 content, yield, and production rate of 70.7%, 0.44 L CH4/g VSadded, and 1.23 L CH4/(L·day), respectively. Bacterial community structure revealed that the richness, diversity, evenness, and dominance of S2 were high except for the archaeal community. The terminal restriction fragments dendrogram also revealed that the microbial community of the acidogenic and methanogenic reactors in S2 was distinct. Therefore, S2 was the best among the systems for the operation of two-stage AD of food waste in terms of CH4 production, nutrient removal, and microbial community structure. PMID:25079836

  6. Studies on the relationship between cyanide-resistant respi-ration and expression of alternative oxidase in mung bean using antibodies prepared by synthetic polypeptide

    Institute of Scientific and Technical Information of China (English)

    LI; Chijun; (

    2001-01-01

    [1]Liang, Z., Liang, H. G., The respiratory metabolism of plants, in Plant Physiology and Molecular Biology (eds. Yu, S. W., Tang, Z. C.) (in Chinese), 2nd ed., Beijing: Science Press, 1998, 344-365.[2]Lü, C. S., Liang, H. G., Induced respiration in melon fruits, Scientia Sinica, 1963, 12(4): 616.[3]Liang, H. G., Lü, C. S., A comparative study of CN-resistant respiration in different cultures of tobacco callus, Plant Physiol., 1984, 75: 876.[4]Elthon, T. E., McIntosh, L., Identification of the alternative terminal oxidase of higher plant mitochondria, Proc. Natl. Acad. Sci. USA, 1987, 84: 8399.[5]Elthon, T. E., Nickels, R. L., McIntosh, L., Monoclonal antibodies to the alternative oxidase of higher plant mitochondria, Plant Physiol., 1989, 89: 1311.[6]Liang, W. S., Liang, H. G., Progress of the alternative oxidase, Chinese Bulletin of Botany (in Chinese), 1997, 14(2): 9.[7]Liang, W. S., Liang, H. G., Induction of alternative oxidase expression by endogenous ethylene in aging potato slices, Acta Phytophysiol. Sin. (in Chinese), 1999, 25(2): 205.[8]He, J. X., Wei, Z. Q., Liang, H. G., Effects of water stress on development, and operation and gene expression of cyanide-resistant respiratory pathway in wheat, Science in China, Ser. C, 1999, 42(3): 300.[9]McIntosh, L., Molecular biology of the alternative oxidase, Plant Physiol., 1994, 105: 781.[10] Wang, J., Zhang, L. X., Liu, Z. L. et al., A possible calcium binding site in D1 protein: A fluorescence and FTIR study of the interaction between lanthanides and a synthetic peptide, Photosynthesis Research, 1995, 44: 297.[11] Li, X. P., Du, L. F., Liang, H. G. et al., Preparation and identification of antidodecapeptide of polypeptide D1 or photosys-tem II reaction center, Prog. Biochem. Biophys. (in Chinese), 1997, 24(3): 283.[12] Wen, J. Q., Liang, H. G., Studies on energy status and mitochondria respiration during growth and senescence of mung bean cotyledons, Physiol

  7. Verb aspect, alternations and quantification

    Directory of Open Access Journals (Sweden)

    Svetla Koeva

    2015-11-01

    Full Text Available Verb aspect, alternations and quantification In this paper we are briefly discuss the nature of Bulgarian verb aspect and argue that the verb aspect pairs are different lexical units with different (although related meaning, different argument structure (reflecting categories, explicitness and referential status of arguments and different sets of semantic and syntactic alternations. The verb prefixes resulting in perfective verbs derivation in some cases can be interpreted as lexical quantifiers as well. Thus the Bulgarian verb aspect is related (in different way both with the potential for the generation of alternations and with the prefixal lexical quantification. It is shown that the scope of the lexical quantification by means of verbal prefixes is the quantified verb phrase and the scope remains constant in all derived alternations. The paper concerns the basic issues of these complex problems, while the detailed description of the conditions satisfying particular alternation or particular lexical quantification are subject of a more detailed study.

  8. Alternative medicine among college students.

    Science.gov (United States)

    Gaedeke, R M; Tootelian, D H; Holst, C

    1999-01-01

    The use of "alternative" medicine has become increasingly popular in the United States. Books devoted to alternative medicine, e.g., Spontaneous Healing and 8 Weeks to Optimum Health, have become best sellers. Nevertheless, relatively few research studies have focused on the subject. This study examined the role of alternative medicine among college students. Issues addressed included students' familiarity with, use of, and perceptions regarding unconventional health therapies. The study substantiated a phenomenon health care providers across the country are discovering: a growing number of Americans with interest and financial resources support the development of "mainstream" alternative medicine programs. Results of the study also suggest that well-respected traditional health care organizations would not suffer reputation damage if they were to offer such programs.

  9. Alternative Approaches for Educating Future Global Marketing Professionals: A Comparison of Foreign Study and Research-Intensive Marketing Programs

    Science.gov (United States)

    Kaufman, Peter A.; Melton, Horace L.; Varner, Iris I.; Hoelscher, Mark; Schmidt, Klaus; Spaulding, Aslihan D.

    2011-01-01

    Using an experiential learning model as a conceptual background, this article discusses characteristics and learning objectives for well-known foreign study programs such as study tours, study abroad, and internships and compares them with a less common overseas program called the "Global Marketing Program" (GMP). GMP involves interdisciplinary…

  10. Nationalism Studies between Methodological Nationalism and Orientalism : An Alternative Approach Illustrated with the Case of El Greco in Toledo, Spain

    NARCIS (Netherlands)

    Storm, H.J.

    2015-01-01

    Methodological nationalism is still dominant in nationalism studies. When studying the construction of national identities, scholars generally limit their study to the borders of one nation-state, while only paying attention to members of that particular nation. Implicitly, foreign actors and influe

  11. The use of complementary and alternative medicines among patients with locally advanced breast cancer – a descriptive study

    Directory of Open Access Journals (Sweden)

    Rakovitch Eileen

    2006-02-01

    Full Text Available Abstract Background Complementary and alternative medicine (CAM use is common among cancer patients. This paper reviews the use of CAM in a series of patients with locally advanced breast cancer (LABC. Methods Women with LABC attending a specialist clinic at a single Canadian cancer centre were identified and approached. Participants completed a self-administered survey regarding CAM usage, beliefs associated with CAM usage, views of their risks of developing recurrent cancer and of dying of breast cancer. Responses were scored and compared between CAM users and non-users. Results Thirty-six patients were approached, 32 completed the questionnaire (response rate 89%. Forty-seven percent of LABC patients were identified as CAM users. CAM users were more likely to be younger, married, in a higher socioeconomic class and of Asian ethnicity than non-users. CAM users were likely to use multiple modalities simultaneously (median 4 with vitamins being the most popular (60%. Motivation for CAM therapy was described as, "assisting their body to heal" (75%, to 'boost the immune system' (56% and to "give a feeling of control with respect to their treatment" (56%. CAM therapy was used concurrently with conventional treatment in 88% of cases, however, 12% of patients felt that CAM could replace their conventional therapy. Psychological evaluation suggests CAM users perceived their risk of dying of breast cancer was similar to that of the non-Cam group (33% vs. 35%, however the CAM group had less severe anxiety and depression. Conclusion The motivation, objectives and benefits of CAM therapy in a selected population of women with LABC are similar to those reported for women diagnosed with early stage breast cancer. CAM users display less anxiety and depression and are less likely to believe they will die of their breast cancer. However the actual benefit to overall and disease free survival has yet to be demonstrated, as well as the possible interactions with

  12. An exploratory study of treated-bed nets in Timor-Leste: patterns of intended and alternative usage

    Directory of Open Access Journals (Sweden)

    Wilder-Smith Annelies

    2011-07-01

    significantly decrease availability of nighttime sleeping space for all family members if distributed nets do not remain within the household. Conclusions Emphasizing that net usage is acceptable and important for all family members regardless of age or gender, and addressing the complex behavioural economics of alternative net usages could have significant impacts on malaria control efforts in Timor-Leste, as the country's programmes make progress towards universal net coverage.

  13. Characterization techniques for fixed-field alternating gradient accelerators and beam studies using the KURRI 150 MeV proton FFAG

    Science.gov (United States)

    Sheehy, S. L.; Kelliher, D. J.; Machida, S.; Rogers, C.; Prior, C. R.; Volat, L.; Haj Tahar, M.; Ishi, Y.; Kuriyama, Y.; Sakamoto, M.; Uesugi, T.; Mori, Y.

    2016-07-01

    In this paper we describe the methods and tools used to characterize a 150 MeV proton scaling fixed field alternating gradient (FFAG) accelerator at Kyoto University Research Reactor Institute. Many of the techniques used are unique to this class of machine and are thus of relevance to any future FFAG accelerator. For the first time we detail systematic studies undertaken to improve the beam quality of the FFAG. The control of beam quality in this manner is crucial to demonstrating high power operation of FFAG accelerators in future.

  14. Relation between bond-length alternation and two-photon absorption of a push pull conjugated molecules: a quantum-chemical study

    Science.gov (United States)

    Bartkowiak, W.; Zaleśny, R.; Leszczynski, J.

    2003-02-01

    The results of the semiempirical study of the structure/property relationships for the two-photon absorption cross-section ( δ) of a series of prototypical π-conjugated push-pull molecules are presented. The calculations of δ for the first charge-transfer (CT) excited state were performed as a function of the bond length alternation (BLA). The molecular hyperpolarizabilities ( β and γ) were calculated using the finite-field (FF) method. The obtained data were analyzed based on the simple two-state models. A strong dependence of δ on the BLA parameter was noticed.

  15. Relation between bond-length alternation and two-photon absorption of a push-pull conjugated molecules: a quantum-chemical study

    Energy Technology Data Exchange (ETDEWEB)

    Bartkowiak, W.; Zalesny, R.; Leszczynski, J

    2003-02-01

    The results of the semiempirical study of the structure/property relationships for the two-photon absorption cross-section ({delta}) of a series of prototypical {pi}-conjugated push-pull molecules are presented. The calculations of {delta} for the first charge-transfer (CT) excited state were performed as a function of the bond length alternation (BLA). The molecular hyperpolarizabilities ({beta} and {gamma}) were calculated using the finite-field (FF) method. The obtained data were analyzed based on the simple two-state models. A strong dependence of {delta} on the BLA parameter was noticed.

  16. A case study of detecting the triplet of 3S1 using superconducting gravimeter records with an alternative data preprocessing technique

    Directory of Open Access Journals (Sweden)

    Wen-Bin Shen

    2012-06-01

    Full Text Available Due to their very low noise levels in the low frequency band (<1 mHz, superconducting gravimeters (SGs are particularly suitable to observe long-period free oscillations of the Earth. This case study is dedicated to the detection of the triplet of the seismic normal mode 3S1 that was excited by the December 26, 2004, Sumatra-Andaman earthquake (Mw = 9.3. Some SG records and the Hilbert-Huang transformation are used as an alternative data preprocessing technique, instead of the traditional detiding method. After removal of atmospheric pressure effects from the original SG records, we applied the Hilbert-Huang transformation to the SG residues, to select the signals that included the frequency band of interest, and to construct a new data series. Then, by applying the multi-station experimental technique to five 273-h-long common new data series recorded at different SG stations, we clearly observed all of the three singlets of the mode 3S1, with the central singlet more evident compared to previous studies. Observations of the low-frequency modes 3S1 (n = 0, 1, 2, ...; l = = 1,2, ... provide constraints on the inner and outer core structure. This case study provides an alternative data-preprocessing approach to observe the splitting frequencies of the low-frequency mode type 3S1 (n = 0, 1, 2, ....

  17. Project on Alternative Systems Study - PASS. Comparison of technology of KBS-3, MLH, VLH and VDH concepts by using an expert group

    International Nuclear Information System (INIS)

    This report constitutes a technical comparison and ranking of four repository concepts for final disposal of spent nuclear fuel, that have been studied by SKB: KBS-3, Medium Long Holes (MLH), Very Long Holes (VLH) and Very Deep Holes (VDH). The technical comparison is part of the project 'Project on Alternative Systems Study, PASS', which was initiated by SKB. With the objective of presenting a ranking of the four concepts. Besides this comparison of Technology the ranking is separately made for Long-term Performance and Safety, and Costs before the merging into one verdict. The ranking regarding Technology was carried out in accordance with the method Analytical Hierarchy Process, AHP, and by the aid of expert judgement in the form of a group consisting of six experts. The AHP method implies that the criteria for comparison are ordered in a hierarchy and that the ranking is carried out by pairwise comparison of the criteria. In the evaluation process a measure of the relative importance of each criterion is obtained. The result of the expert judgement exercise was that each expert individually ranked the four concepts in the following order with the top ranked alternative first: KBS-3, MLH, VLH and VDH. The common opinion among the experts was that the top ranking of KBS-3 is significant and the the major criteria used in the study could change substantially without changing the top ranking of KBS-3

  18. Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH)

    Energy Technology Data Exchange (ETDEWEB)

    Lilienblum, W. [Dr. Lilienblum Consulting Toxicology LiCoTox, Hemmingen/Han (Germany); Dekant, W. [University of Wuerzburg, Institute of Toxicology, Wuerzburg (Germany); Foth, H. [University of Halle, Institute of Environmental Toxicology, Halle/Saale (Germany); Gebel, T. [Federal Institute for Occupational Safety and Health, Dortmund (Germany); Hengstler, J.G. [University of Dortmund, Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund (Germany); Kahl, R. [Heinrich-Heine-University, Institute of Toxicology, PO Box 101007, Duesseldorf (Germany); Kramer, P.J. [Merck KGaA, Institute of Toxicology, Darmstadt (Germany); Schweinfurth, H. [Nonclinical Drug Safety, Bayer Schering Pharma AG, Berlin (Germany); Wollin, K.M. [Lower Saxony Governmental Institute of Public Health, Hannover (Germany)

    2008-04-15

    During the last two decades, substantial efforts have been made towards the development and international acceptance of alternative methods to safety studies using laboratory animals. In the EU, challenging timelines for phasing out of many standard tests using laboratory animals were established in the seventh Amending Directive 2003/15/EC to Cosmetics Directive 76/768/EEC. In continuation of this policy, the new European Chemicals Legislation (REACH) favours alternative methods to conventional in vivo testing, if validated and appropriate. Even alternative methods in the status of prevalidation or validation, but without scientific or regulatory acceptance may be used under certain conditions. Considerable progress in the establishment of alternative methods has been made in some fields, in particular with respect to methods predicting local toxic effects and genotoxicity. In more complex important fields of safety and risk assessment such as systemic single and repeated dose toxicity, toxicokinetics, sensitisation, reproductive toxicity and carcinogenicity, it is expected that the development and validation of in silico methods, testing batteries (in vitro and in silico) and tiered testing systems will have to overcome many scientific and regulatory obstacles which makes it extremely difficult to predict the outcome and the time needed. The main reasons are the complexity and limited knowledge of the biological processes involved on one hand and the long time frame until validation and regulatory acceptance of an alternative method on the other. New approaches in safety testing and evaluation using 'Integrated Testing Strategies' (ITS) (including combinations of existing data, the use of chemical categories/grouping, in vitro tests and QSAR) that have not been validated or not gained wide acceptance in the scientific community and by regulatory authorities will need a thorough justification of their appropriateness for a given purpose. This requires

  19. A Review of Chemical Bonding Studies: Needs, Aims, Methods of Exploring Students' Conceptions, General Knowledge Claims and Students' Alternative Conceptions

    Science.gov (United States)

    Unal, Suat; Calik, Muammer; Ayas, Alipasa; Coll, Richard K.

    2006-01-01

    The present paper presents a detailed thematic review of chemical bonding studies. To achieve this, a matrix is developed to summarize and present the findings by focusing on insights derived from the related studies. The matrix incorporates the following themes: needs, aims, methods of exploring students' conceptions, general knowledge claims,…

  20. The Learning and Competency Development of Master Teachers in Alternative High Schools for At-Risk Youth: A Case Study

    Science.gov (United States)

    Williams, Nida W.

    2012-01-01

    This qualitative case study was designed to explore how master teachers in transfer high schools learn the competencies they perceive are required to engage at-risk students so that they persist and graduate. The study is based on the following assumptions: (1) The requisite teacher competencies can be defined and identified and, in fact,…

  1. Alternatives for Mixed-Effects Meta-Regression Models in the Reliability Generalization Approach: A Simulation Study

    Science.gov (United States)

    López-López, José Antonio; Botella, Juan; Sánchez-Meca, Julio; Marín-Martínez, Fulgencio

    2013-01-01

    Since heterogeneity between reliability coefficients is usually found in reliability generalization studies, moderator analyses constitute a crucial step for that meta-analytic approach. In this study, different procedures for conducting mixed-effects meta-regression analyses were compared. Specifically, four transformation methods for the…

  2. Observational Study Designs for Comparative Effectiveness Research: An Alternative Approach to Close Evidence Gaps in Head-and-Neck Cancer

    International Nuclear Information System (INIS)

    Comparative effectiveness research (CER) has emerged as an approach to improve quality of care and patient outcomes while reducing healthcare costs by providing evidence to guide healthcare decisions. Randomized controlled trials (RCTs) have represented the ideal study design to support treatment decisions in head-and-neck (H and N) cancers. In RCTs, formal chance (randomization) determines treatment allocation, which prevents selection bias from distorting the measure of treatment effects. Despite this advantage, only a minority of patients qualify for inclusion in H and N RCTs, which limits the validity of their results to the broader H and N cancer patient population seen in clinical practice. Randomized controlled trials often do not address other knowledge gaps in the management of H and N cancer, including treatment comparisons for rare types of H and N cancers, monitoring of rare or late toxicity events (eg, osteoradionecrosis), or in some instances an RCT is simply not feasible. Observational studies, or studies in which treatment allocation occurs independently of investigators' choice or randomization, may address several of these gaps in knowledge, thereby complementing the role of RCTs. This critical review discusses how observational CER studies complement RCTs in generating the evidence to inform healthcare decisions and improve the quality of care and outcomes of H and N cancer patients. Review topics include a balanced discussion about the strengths and limitations of both RCT and observational CER study designs; a brief description of design and analytic techniques to handle selection bias in observational studies; examples of observational studies that inform current clinical practices and management of H and N cancers; and suggestions for relevant CER questions that could be addressed by an observational study design

  3. Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice

    Directory of Open Access Journals (Sweden)

    Holers V Michael

    2007-05-01

    Full Text Available Abstract Background The posttraumatic response to traumatic brain injury (TBI is characterized, in part, by activation of the innate immune response, including the complement system. We have recently shown that mice devoid of a functional alternative pathway of complement activation (factor B-/- mice are protected from complement-mediated neuroinflammation and neuropathology after TBI. In the present study, we extrapolated this knowledge from studies in genetically engineered mice to a pharmacological approach using a monoclonal anti-factor B antibody. This neutralizing antibody represents a specific and potent inhibitor of the alternative complement pathway in mice. Methods A focal trauma was applied to the left hemisphere of C57BL/6 mice (n = 89 using a standardized electric weight-drop model. Animals were randomly assigned to two treatment groups: (1 Systemic injection of 1 mg monoclonal anti-factor B antibody (mAb 1379 in 400 μl phosphate-buffered saline (PBS at 1 hour and 24 hours after trauma; (2 Systemic injection of vehicle only (400 μl PBS, as placebo control, at identical time-points after trauma. Sham-operated and untreated mice served as additional negative controls. Evaluation of neurological scores and analysis of brain tissue specimens and serum samples was performed at defined time-points for up to 1 week. Complement activation in serum was assessed by zymosan assay and by murine C5a ELISA. Brain samples were analyzed by immunohistochemistry, terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL histochemistry, and real-time RT-PCR. Results The mAb 1379 leads to a significant inhibition of alternative pathway complement activity and to significantly attenuated C5a levels in serum, as compared to head-injured placebo-treated control mice. TBI induced histomorphological signs of neuroinflammation and neuronal apoptosis in the injured brain hemisphere of placebo-treated control mice for up to 7 days. In contrast, the

  4. Study on the Current Status of Medical Alternative Animal Researches%医学动物替代研究发展现状研究

    Institute of Scientific and Technical Information of China (English)

    卫茂玲

    2016-01-01

    目的:了解我国动物替代研究发展现状,发现问题,提出对策。方法文献检索与定性描述法。以主题、篇名或关键词“动物替代”或“动物减少”或“动物优化”精确检索中文医学常用数据库中国知网、维普数据和万方数据库,补充查找相关研究参考文献。纳入分析组织建设、立法、医学教育和替代研究方法文献,并进行定性描述概括,检索时间截止2015年7月20日。结果初检引文219条,文献发表于1999-2014年,以描述性研究为主。动物替代研究领域包括皮肤刺激、眼刺激毒理学检测、热敏试验和动物模型替代等。替代研究信息交流平台已建立,部分教师已经在实践运用替代原则,相关专著已出版,但法规建设和验证体系滞后,替代研究认识还不乐观,验证方法研究不多。结论国内动物替代研究不多,缺乏系统化建设。未来应加强动物替代研究体系研究,重点在立法、政策引导、医学教育、人才培养和研究方法等。%Objective:To investigate the current status of alternative animal researches in China and thus find the problems and put forward countermeasures. Method: This study was carried out by the methods of literature search and qualitative description. The authors precisely searched the medicine databases commonly used in China ( CNKI, VIP, and Wanfang Data) using the MeSH word, title, or keyword namely"animal alternative","animal decrease" or"animal optimization", and added to find the related researches′references. Then the author included the literature regarding to the organization construction, legislation, medical education, and alternative research methods, and conducted a qualitative description. The deadline was July 20, 2015. Results:There were 219 ini-tial quotations published from 1999 to 2014, and mainly were descriptive researches. The fields of alternative ani-mal researches included skin

  5. 医学动物替代研究发展现状研究%Study on the Current Status of Medical Alternative Animal Researches

    Institute of Scientific and Technical Information of China (English)

    卫茂玲

    2016-01-01

    Objective:To investigate the current status of alternative animal researches in China and thus find the problems and put forward countermeasures. Method: This study was carried out by the methods of literature search and qualitative description. The authors precisely searched the medicine databases commonly used in China ( CNKI, VIP, and Wanfang Data) using the MeSH word, title, or keyword namely"animal alternative","animal decrease" or"animal optimization", and added to find the related researches′references. Then the author included the literature regarding to the organization construction, legislation, medical education, and alternative research methods, and conducted a qualitative description. The deadline was July 20, 2015. Results:There were 219 ini-tial quotations published from 1999 to 2014, and mainly were descriptive researches. The fields of alternative ani-mal researches included skin and eye stimulating toxicology test, thermal hyperalgesia and animal model replace-ment, and etc. The information communication platform of replacement researches had established, part of teachers were in practice using the substitution principle, the related monographs had been published, but the law and regu-lation construction and validation system were lag, the cognitive of replacement researches was not optimistic, and the validation method researches were insufficient. Conclusion: The domestic alternative animal researches were insufficient and lacking of systematic construction. It should strengthen the study on alternative animal research sys-tem, focused on legislation, policy leading, medical education, talent cultivation, and research methods.%目的:了解我国动物替代研究发展现状,发现问题,提出对策。方法文献检索与定性描述法。以主题、篇名或关键词“动物替代”或“动物减少”或“动物优化”精确检索中文医学常用数据库中国知网、维普数据和万方数据库,补充查找相关研

  6. The use of complementary and alternative medicine by patients with diabetes mellitus in Bahrain: a cross-sectional study.

    LENUS (Irish Health Repository)

    Khalaf, Abeer J

    2010-01-01

    CAM use is widespread, especially among patients with diabetes. The Gulf States have a high prevalence of diabetes, alongside a long tradition of CAM use. The aim of this study is to establish the prevalence of CAM use among patients with diabetes mellitus in Bahrain and to examine the characteristics of the CAM users.

  7. Reliability of Scores on the "Manifestation of Symptomatology Scale": A Study with Adolescent Students in an Alternative School Setting

    Science.gov (United States)

    Sullivan, Jeremy R.; Moyer, Michael S.; Gonzalez, Gerardo E.

    2011-01-01

    The "Manifestation of Symptomatology Scale" (MOSS) is a norm-referenced, self-report instrument designed to assess characteristics of psychopathology among children and adolescents from 11 to 18 years of age. Although the MOSS has been used in several research studies within juvenile justice or disciplinary education contexts, the psychometric…

  8. Linear, Non-Linear and Alternative Algorithms in the Correlation of IEQ Factors with Global Comfort: A Case Study

    Directory of Open Access Journals (Sweden)

    Francesco Fassio

    2014-11-01

    Full Text Available Indoor environmental quality (IEQ factors usually considered in engineering studies, i.e., thermal, acoustical, visual comfort and indoor air quality are individually associated with the occupant satisfaction level on the basis of well-established relationships. On the other hand, the full understanding of how single IEQ factors contribute and interact to determine the overall occupant satisfaction (global comfort is currently an open field of research. The lack of a shared approach in treating the subject depends on many aspects: absence of established protocols for the collection of subjective and objective measurements, the amount of variables to consider and in general the complexity of the technical issues involved. This case study is aimed to perform a comparison between some of the models available, studying the results of a survey conducted with objective and subjective method on a classroom within University of Roma TRE premises. Different models are fitted on the same measured values, allowing comparison between different weighting schemes between IEQ categories obtained with different methods. The critical issues, like differences in the weighting scheme obtained with different IEQ models and the variability of the weighting scheme with respect to the time of exposure of the users in the building, identified during this small scale comfort assessment study, provide the basis for a survey activity on a larger scale, basis for the development of an improved IEQ assessment method.

  9. Exploring Alternative Ways of Assessing Prior Knowledge, Its Components and Their Relation to Student Achievement: A Mathematics Based Case Study

    Science.gov (United States)

    Hailikari, Telle; Nevgi, Anne; Lindblom-Ylanne, Sari

    2007-01-01

    This study investigates how different types of prior knowledge influence student achievement and how different assessment measures influence the observed effect of prior knowledge. We introduce a model of prior knowledge that distinguishes between different types of prior knowledge and uses different assessment measures to assess different types…

  10. Examining alternative scoring rubrics on a statewide test: The impact of different scoring methods on science and social studies performance assessments

    Science.gov (United States)

    Creighton, Susan Dabney

    There is no consensus regarding the most reliable and valid scoring methods for the assessment of higher order thinking skills. Most of the research on alternative formats has focused on the scoring of writing ability. This study examined the value of different types of performance assessment scoring guides on state mandated science and social studies tests. A proportional stratified sample of raters were randomly assigned to one of four scoring groups: checklist, analytic rubric, holistic rubric, and generic rubrics. A fifth method, the weighted analytic rubric, was included by applying an algorithmic formula to the scores assigned by raters using the analytic rubric. A comparison of the mean scores for the five scoring groups suggests that there may be a difference in the way raters applied the rubric for each group. Although the literature suggests that it is possible to achieve high levels of inter-rater reliability, across forms of scoring, phi coefficients of moderate strength were obtained for three of the four constructed-response items. Results for each scoring group were compared indicating that item complexity may impact the level of inter-rate, reliability and the selection of the most reliable rubric for each discipline. Analytic rubrics appear to achieve more reliable results with less complex items. A multitrait-multimethod approach was utilized to investigate the external validity of the social studies and science tasks. As expected, there tended to be a stronger association between the PACT science constructed-response scores with scores based on science multiple-choice scores than between the science constructed-response scores and the writing ability subtest scores. A similar pattern was seen with social studies items. These results provide some evidence for the validity of the performance assessments. A post study survey completed by raters provided qualitative information regarding their thought processes and their primary focus during the

  11. Solar cooking - Practice of use and disuse of alternative technology. A case-based study of users and disusers of box solar cookers in urban Gujarat, India

    Energy Technology Data Exchange (ETDEWEB)

    Ahmad, B.

    2000-10-01

    Solar cooking technology is generally known for its multiple benefits, but also for its slow or lack of diffusion among user groups. It is this paradox that is the theme of this thesis. Use and disuse of alternative technologies is the central issue of the study. Arational aspects as well as rational issues significantly affects practice of use and disuse of alternative technologies. In this study the limits and details of these arationalities and rationalities are investigated. The empirical part of the study was carried out in Gujarat, India, where abouth 45,000 families have a functioning box solar cooker at their homes (about 1% of urban families). These families enjoy numerous favourable conditions for solar cooking: 1) About 270 sunny days per year; 2) Staple foods like rice and dal are possible to be cooked by solar cooker; 3) Solar cookers are robust and are technically functional after several years of use; 4) Maintenance and operation of solar cookers is easy and does not pose significant constraints to the users; 5) Economic saving of abouth 30% of cooking fuel (1999 prices) on year basis is achievable by users, if the solar cooker were used for one meal on sunny days; 6) Culturally, use of sun for cooking is not seen as negative; 7) The solar cookers are locally manufactured and sold at local sale outlets at 750 Indian Rupees. The price is after 50% subsidy and is affordable for the middle class urban families. 8) Solar cooker has more than two decades of history in Gujarat. During last 20 years Gujarat State has constantly striven to introduce solar cookers to families in Gujarat. In this regard at both national and international levels, Gujarat State is not only a pioneer, but also on development, introduction and implementation of solar cookers the State is often referred to as model. The question is not how to encourage other families to buy a solar cooker, but rather why most of those who have purchased a solar cooker do not use their solar cookers

  12. The influence of alternative pedagogical methods in postsecondary biology education: How do students experience a multimedia case-study environment?

    Science.gov (United States)

    Wolter, Bjorn Hugo Karl

    The purpose of this study was to better understand how an online, multimedia case study method influenced students' motivation, performance, and perceptions of science in collegiate level biology classes. It utilized a mix-methods design including data from pre- and post-test, student surveys, and focus group interviews to answer one primary question, did participation in the affect student performance? Two sub-questions were: (a) did participation affect persistence? and (b) did students believe it to be a good learning experience? One hundred and eight students in 5 classes from 4 campuses in the United States and Puerto Rico participated in this study during spring semester 2009. After receiving instruction on HIV, students took a 6 questions pre-test to measure their initial knowledge of both HIV and lab procedures. Participants then engaged in the Case It! learning environment, where they watched case-studies on HIV, used virtual lab tools, created an online poster of their findings, and role-played as both family members and physicians about their case. A post-test identical to the pre-test was given to students upon completion. Both were then scored using rubrics and analyzed via paired t-Tests and ANOVA. The researcher visited all 4 study sites to conduct both the focus group interviews and student surveys. Student surveys were quantified and descriptive statistics generated. Focus group interviews were video recorded, transcribed, and inductively and deductively coded. Student knowledge increased because of participation, and the majority of students said they found the Case It! project to be both a good learning experience (95%) and one that would help with future classes or careers (87%). Based on student interviews, the Case It! project did have a beneficial impact on students' intentions to persist as science majors. Many students noted that the learning environment created an overall context in which they could apply knowledge from multiple classes

  13. Nitrous oxide and methane emissions from optimized and alternative cereal cropping systems on the North China Plain: A two-year field study

    Energy Technology Data Exchange (ETDEWEB)

    Gao, Bing [College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193 (China); Ju, Xiaotang, E-mail: juxt@cau.edu.cn [College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193 (China); Su, Fang; Meng, Qingfeng [College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193 (China); Oenema, Oene [Wageningen University and Research, Alterra, Wageningen (Netherlands); Christie, Peter [College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193 (China); Agri-Environment Branch, Agri-Food and Biosciences Institute, Belfast BT9 5PX (United Kingdom); Chen, Xinping; Zhang, Fusuo [College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193 (China)

    2014-02-01

    The impacts of different crop rotation systems with their corresponding management practices on grain yield, greenhouse gas emissions, and fertilizer nitrogen (N) and irrigation water use efficiencies are not well documented. This holds especially for the North China Plain which provides the staple food for hundreds of millions of people and where groundwater resources are polluted with nitrate and depleted through irrigation. Here, we report on fertilizer N and irrigation water use, grain yields, and nitrous oxide (N{sub 2}O) and methane (CH{sub 4}) emissions of conventional and optimized winter wheat–summer maize double-cropping systems, and of three alternative cropping systems, namely a winter wheat–summer maize (or soybean)–spring maize system, with three harvests in two years; and a single spring maize system with one crop per year. The results of this two-year study show that the optimized double-cropping system led to a significant increase in grain yields and a significant decrease in fertilizer N use and net greenhouse gas intensity, but the net greenhouse gas N{sub 2}O emissions plus CH{sub 4} uptake and the use of irrigation water did not decrease relative to the conventional system. Compared to the conventional system the net greenhouse gas emissions, net greenhouse gas intensity and use of fertilizer N and irrigation water decreased in the three alternative cropping systems, but at the cost of grain yields except in the winter wheat–summer maize–spring maize system. Net uptake of CH{sub 4} by the soil was little affected by cropping system. Average N{sub 2}O emission factors were only 0.17% for winter wheat and 0.53% for maize. In conclusion, the winter wheat–summer maize–spring maize system has considerable potential to decrease water and N use and decrease N{sub 2}O emissions while maintaining high grain yields and sustainable use of groundwater. - Highlights: • Yields, resource use efficiency and N{sub 2}O + CH{sub 4} emission

  14. Alternative investments: return driving actors

    OpenAIRE

    Elliott, K; G. Marcato

    2011-01-01

    In an asset allocation process, correlations are particularly important if one includes 'alternative investments' such as real estate, commodities and hedge funds, which have been proclaimed to provide diversifying benefits within the overall portfolio context. However, by looking at correlations between asset classes alone some diversification benefits may be over or under-stated. More recently, finance literature has focused on alternative asset classes to study their behaviour and to ident...

  15. The neurogenetics of alternative splicing

    OpenAIRE

    Vuong, CK; Black, DL; S. Zheng

    2016-01-01

    Alternative precursor-mRNA splicing is a key mechanism for regulating gene expression in mammals and is controlled by specialized RNA-binding proteins. The misregulation of splicing is implicated in multiple neurological disorders. We describe recent mouse genetic studies of alternative splicing that reveal its critical role in both neuronal development and the function of mature neurons. We discuss the challenges in understanding the extensive genetic programmes controlled by proteins that r...

  16. Sustainable Tourism – An Economic Reviving Alternative of the Under-Developed Areas. Case Study – Straja Resort

    OpenAIRE

    Aurel Gheorghilas; Bianca Dumitrescu; Anda Nicoleta Onetiu

    2011-01-01

    The tourism development of an area is an ongoing process of designing tourism facilities, the renewal of the existing ones, their dimensioning according to the changes of the tourism demand and supply and most important rendering the tourism activity efficient. According to the realities of the geographical space, the focus of the present study rivets on differentiating certain typologies and principles of tourism development in an area strongly affected by the economic streamlining following...

  17. Positive psychology as an alternative to traditional clinical approach to study of quality of life in people with physical disabilities

    OpenAIRE

    Lebedeva A. A.

    2012-01-01

    The article is devoted to overview studies of quality of life in people with physical disabilities. The scientists are mainly focused on the health limitations as affecting their quality of life. As a fact, disabled people need regular medical help, procedures of rehabilitation and prophylaxis of medical consequences of their disability. This paper addresses the subject from the perspective of positive approaches to development of personality and quality of life in people with disabilities. P...

  18. An open-label, randomized bioavailability study with alternative methods of administration of crushed ticagrelor tablets in healthy volunteers

    OpenAIRE

    Teng, Renli; Carlson, Glenn; Hsia, Judith

    2014-01-01

    Objective: To compare the bioavailability and safety profile of crushed ticagrelor tablets suspended in water and administered orally or via nasogastric tube, with that of whole tablets administered orally. Methods: In this single-center, open-label, randomized, three-treatment crossover study, 36 healthy volunteers were randomized to receive a single 90-mg dose of ticagrelor administered orally as a whole tablet or as crushed tablets suspended in water and given orally or via a nasogastric t...

  19. OBSERVATIONAL STUDY ON SUB ARACHNOID BLOCK IN PRE SUBDUED CHILDREN IS A CHEAP, EFFECTIVE, SAFE ALTERNATIVE TO GENERAL ANAESTHESIA

    OpenAIRE

    Srilakshmi; Venkata Ramana

    2014-01-01

    Technically, carrying out Spinal Anaesthesia in adults, may not pose much problems, because of patient co-operation, but same is not always so in case of toddlers and children, because of inherent fear of Hospital atmosphere, detachment from parents, immaturity and other. This study aims at performing Spinal Anaesthesia, in children, if they are pre-medicated, and pre-subdued, might pave way for the comfort of both patient and Anesthesiologists. So, pre-medicated, pre-subdued ...

  20. Feasibility study for alternate fuels production: unconventional natural gas from wastewater treatment plants. Volume II, Appendix D. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Overly, P.; Tawiah, K.

    1981-12-01

    Data are presented from a study performed to determined the feasibility of recovering methane from sewage at a typical biological secondary wastewater treatment plant. Three tasks are involved: optimization of digester gas; digester gas scrubbing; and application to the East Bay Municipal Utility District water pollution control plant. Results indicate that excess digester gas can be used economically at the wastewater treatment plant and that distribution and scrubbing can be complex and costly. (DMC) 193 references, 93 figures, 26 tables.

  1. Continuous Wavelet Transform, a powerful alternative to Derivative Spectrophotometry in analysis of binary and ternary mixtures: A comparative study.

    Science.gov (United States)

    Elzanfaly, Eman S; Hassan, Said A; Salem, Maissa Y; El-Zeany, Badr A

    2015-12-01

    A comparative study was established between two signal processing techniques showing the theoretical algorithm for each method and making a comparison between them to indicate the advantages and limitations. The methods under study are Numerical Differentiation (ND) and Continuous Wavelet Transform (CWT). These methods were studied as spectrophotometric resolution tools for simultaneous analysis of binary and ternary mixtures. To present the comparison, the two methods were applied for the resolution of Bisoprolol (BIS) and Hydrochlorothiazide (HCT) in their binary mixture and for the analysis of Amlodipine (AML), Aliskiren (ALI) and Hydrochlorothiazide (HCT) as an example for ternary mixtures. By comparing the results in laboratory prepared mixtures, it was proven that CWT technique is more efficient and advantageous in analysis of mixtures with severe overlapped spectra than ND. The CWT was applied for quantitative determination of the drugs in their pharmaceutical formulations and validated according to the ICH guidelines where accuracy, precision, repeatability and robustness were found to be within the acceptable limit. PMID:26186613

  2. Complementary and Alternative Medicine

    Science.gov (United States)

    ... Help a Friend Who Cuts? Complementary and Alternative Medicine KidsHealth > For Teens > Complementary and Alternative Medicine Print ... replacement. continue How Is CAM Different From Conventional Medicine? Conventional medicine is based on scientific knowledge of ...

  3. Alternative medicine - pain relief

    Science.gov (United States)

    Alternative medicine refers to treatments that are used instead of conventional (standard) ones. If you use an alternative ... considered complementary therapy. There are many forms of ... Acupuncture involves stimulating certain acupoints on the body ...

  4. Managing visitor impacts in parks: A multi-method study of the effectiveness of alternative management practices

    Science.gov (United States)

    Park, L.O.; Marion, J.L.; Manning, R.E.; Lawson, S.R.; Jacobi, C.

    2008-01-01

    How can recreation use be managed to control associated environmental impacts? What management practices are most effective and why? This study explored these and related questions through a series of experimental ?treatments? and associated ?controls? at the summit of Cadillac Mountain in Acadia National Park, a heavily used and environmentally fragile area. The treatments included five management practices designed to keep visitors on maintained trails, and these practices ranged from ?indirect? (information/education) to ?direct? (a fence bordering the trail). Research methods included unobtrusive observation of visitors to determine the percentage of visitors who walked off-trail and a follow-up visitor survey to explore why management practices did or didn?t work. All of the management practices reduced the percentage of visitors who walked off-trail. More aggressive applications of indirect practices were more effective than less aggressive applications, and the direct management practice of fencing was the most effective of all. None of the indirect management practices reduced walking off-trail to a degree that is likely to control damage to soil and vegetation at the study site. Study findings suggest that an integrated suite of direct and indirect management practices be implemented on Cadillac Mountain (and other, similar sites) that includes a) a regulation requiring visitors to stay on the maintained trail, b) enforcement of this regulation as needed, c) unobtrusive fencing along the margins of the trail, d) redesign of the trail to extend it, widen it in key places, and provide short spur trails to key ?photo points?, and e) an aggressive information/education program to inform visitors of the regulation to stay on the trail and the reasons for it. These recommendations are a manifestation of what may be an emerging principle of park and outdoor recreation management: intensive use requires intensive management.

  5. Myoinositol as a Safe and Alternative Approach in the Treatment of Infertile PCOS Women: A German Observational Study

    Science.gov (United States)

    Schindler, Adolf Eduard

    2016-01-01

    The use of 2 × 2000 mg myoinositol + 2 × 200 μg folic acid per day is a safe and promising tool in the effective improvement of symptoms and infertility for patients with a polycystic ovary syndrome (PCOS). Using a questionnaire an observational study was performed under German gynecologists to collect data on ovulation and pregnancy rates in PCOS patients with infertility. In this observational study, 3602 infertile women used myoinositol and folic acid between 2 and 3 months in a dosage of 2 × 2000 mg myoinositol + 2 × 200 μg folic acid per day. In a subgroup of 32 patients, hormonal values for testosterone, free testosterone, and progesterone were analyzed before and after 12 weeks of treatment. The mean time of use was 10.2 weeks. During this time 70% of these women had a restored ovulation, and 545 pregnancies were obtained. This means a pregnancy rate of 15.1% of all the myoinositol and folic acid users. In 19 cases a concomitant medication with clomiphene or dexamethasone was used. One twin pregnancy was documented. Testosterone levels changed from 96.6 ng/ml to 43.3 ng/ml and progesterone from 2.1 ng/ml to 12.3 ng/ml (p PCOS and infertility is available. The achieved pregnancy rates are at least in an equivalent or even superior range than those reported by the use of metformin. PMID:27642297

  6. Final report study of alternatives for future operations of the naval petroleum and oil shale reserves NPR-2, California

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-01

    The US Department of Energy (DOE) has asked Gustavson Associates, Inc. to serve as an Independent Petroleum Consultant under contract DE-AC01-96FE64202. This authorizes a study and recommendations regarding future development of Naval Petroleum Reserve No. 2 (NPR-2) in Kern County, California. The report that follows is the Phase II Final Report for that study. Additional details are provided in the Addendum (the Phase I Property Description and Fact Finding Report). The key property elements that positively affect the estimated value of NPR-2 include the following: royalty income from producing oil and gas leases, rental income from non-producing oil and gas leases, income from grazing or leasing of grazing rights, potential income from oil and gas leasing on exploratory (or nonprospective) acreage, potential value of trading surface real estate as ranch land for sheep grazing (10,044 acres), and town lots for residential or commercial development (16.7 acres). Key elements that negatively impact the estimated value include: environmental assessment costs, operating budgets, and lease sale expenses.

  7. Alternative uses of a megavolt tandem accelerator for few-keV studies with ion-source SIMS monitoring

    Science.gov (United States)

    Mello, S. L. A.; Codeço, C. F. S.; Magnani, B. F.; Sant'Anna, M. M.

    2016-06-01

    We increase the versatility of a tandem electrostatic accelerator by implementing simple modifications to the standard operation procedure. While keeping its ability to deliver MeV ion beams, we show that the experimental setup can (i) provide good quality ion beams in the few-keV energy range and (ii) be used to study ion-beam surface modification with simultaneous secondary ion mass spectrometry. This latter task is accomplished without using any chamber connected to the accelerator exit. We perform mass spectrometry of the few-keV anions produced in the ion source by measuring their neutral counterparts at the accelerator exit with energies up to 1.7 MeV. With an additional modification, a high-current few-keV regime is obtained, using the ion source as an irradiation chamber and the accelerator itself only as a mass spectrometer. As an example of application, we prepare a sample for the study of ion-beam assisted dewetting of a thin Au film on a Si substrate.

  8. Calomys callosus: an alternative model to study fibrosis in Schistosomiasis mansoni: the pathology of the acute phase

    Directory of Open Access Journals (Sweden)

    J. A. Lenzi

    1995-04-01

    Full Text Available Twenty Calomys callosus, Rengger, 1830 (Rodentia-Cricetidae were studied in the early stage of the acute schistosomal mansoni infection (42nd day. The same number of Swiss Webster mice were used as a comparative standard. Liver and intestinal sections, fixed in formalin-Millonig and embedded in paraffin, were stained with hematoxilin and eosin, PAS-Alcian Blue, pH = 1.0 and 2.5, Lennert's Giemsa, Picrosirius plus polarization microscopy, Periodic acid methanamine silver, Gomori's silver reticulin and resorcin-fuchsin. Immunohistological study (indirect immunofluorescence and peroxidase labeled extravidin-biotin methods was done with antibodies specific to pro-collagen III, fibronectin, elastin, condroitin-sulfate, tenascin, alpha smooth muscle actin, vimentin and desmin. The hepatic granulomas were small, reaching only 27 of the volume of the hepatic Swiss Webster granuloma. They were composed mainly by large immature macrophages, often filled by schistosomal pigment, characterizing an exsudative-macrophage granuloma type. The granulomas were situated in the parenchyma and in the portal space. They were often intravascular, poor of extracellular matrix components, except fibronectin and presented, sometimes alpha smooth muscle actin and vimentin positive cells. The C. callosus intestinal granulomas were similar to Swiss Webster, showing predominance of macrophages. Therefore, the C. callosus acquire very well the Schistosoma mansoni infection, without developing strong hepatic acute granulomatous reaction, suggesting lack of histopathological signs of hypersensitivity.

  9. Evolution of alternative splicing after gene duplication

    OpenAIRE

    Su, Zhixi; Wang, Jianmin; Yu, Jun; Huang, Xiaoqiu; Gu, Xun

    2006-01-01

    Alternative splicing and gene duplication are two major sources of proteomic function diversity. Here, we study the evolutionary trend of alternative splicing after gene duplication by analyzing the alternative splicing differences between duplicate genes. We observed that duplicate genes have fewer alternative splice (AS) forms than single-copy genes, and that a negative correlation exists between the mean number of AS forms and the gene family size. Interestingly, we found that the loss of ...

  10. Thermodynamic and transport properties of some alternative ozone-safe refrigerants for industrial refrigeration equipment: Study in Belarus and Ukraine

    Science.gov (United States)

    Grebenkov, A. J.; Zhelezny, V. P.; Klepatsky, P. M.; Beljajeva, O. V.; Chernjak, Yu. A.; Kotelevsky, Yu. G.; Timofejev, B. D.

    1996-05-01

    The study of several hydrofluorocarbons (HFC) and fluorocarbons (FC) and their binary mixtures that have no ozone-depleting ability is being carried Out in the framework of Belarus National Program. The fluids include HFCs R134a. R152a, R135, and R32, and FC R218. The following properties are being investigated: ( I ) phase equilibrium parameters including the boiling and condensing curve and critical point, thermophysical properties at these parameters, and heat of evaporation: (2) isobaric and isochoric heat capacity, ethalpy, and entropy in the gas and liquid state: (3) speed of sound, thermal conductivity. viscosity, and density in the gas and liquid state: (4) dielectric properties and surface tension: (5) behavior of combined construction materials inside the refrigerant medium: and (6) solubility in compressor oils and other technological characteristics. The series of results obtained by authors during the period 1990 1993 is presented.

  11. Balancing Conservation with National Development: A Socio-Economic Case Study of the Alternatives to the Serengeti Road.

    Science.gov (United States)

    Hopcraft, J Grant C; Bigurube, Gerald; Lembeli, James Daudi; Borner, Markus

    2015-01-01

    Developing countries often have rich natural resources but poor infrastructure to capitalize on them, which leads to significant challenges in terms of balancing poverty alleviation with conservation. The underlying premise in development strategies is to increase the socio-economic welfare of the people while simultaneously ensuring environmental sustainability, however these objectives are often in direct conflict. National progress is dependent on developing infrastructure such as effective transportation networks, however roads can be ecologically catastrophic in terms of disrupting habitat connectivity and facilitating illegal activity. How can national development and conservation be balanced? The proposed Serengeti road epitomizes the conflict between poverty alleviation on one hand, and the conservation of a critical ecosystem on the other. We use the Serengeti as an exemplar case-study in which the relative economic and social benefits of a road can be assessed against the ecological impacts. Specifically, we compare three possible transportation routes and ask which route maximizes the socio-economic returns for the people while minimizing the ecological costs. The findings suggest that one route in particular that circumnavigates the Serengeti links the greatest number of small and medium sized entrepreneurial businesses to the largest labour force in the region. Furthermore, this route connects the most children to schools, provisions the greatest access to hospitals, and opens the most fertile crop and livestock production areas, and does not compromise the ecology and tourism revenue of the Serengeti. This route would improve Tanzania's food security and self-reliance and would facilitate future infrastructure development which would not be possible if the road were to pass through the Serengeti. This case study provides a compelling example of how a detailed spatial analysis can balance the national objectives of poverty alleviation while maintaining

  12. Balancing Conservation with National Development: A Socio-Economic Case Study of the Alternatives to the Serengeti Road

    Science.gov (United States)

    Hopcraft, J. Grant C.; Bigurube, Gerald; Lembeli, James Daudi; Borner, Markus

    2015-01-01

    Developing countries often have rich natural resources but poor infrastructure to capitalize on them, which leads to significant challenges in terms of balancing poverty alleviation with conservation. The underlying premise in development strategies is to increase the socio-economic welfare of the people while simultaneously ensuring environmental sustainability, however these objectives are often in direct conflict. National progress is dependent on developing infrastructure such as effective transportation networks, however roads can be ecologically catastrophic in terms of disrupting habitat connectivity and facilitating illegal activity. How can national development and conservation be balanced? The proposed Serengeti road epitomizes the conflict between poverty alleviation on one hand, and the conservation of a critical ecosystem on the other. We use the Serengeti as an exemplar case-study in which the relative economic and social benefits of a road can be assessed against the ecological impacts. Specifically, we compare three possible transportation routes and ask which route maximizes the socio-economic returns for the people while minimizing the ecological costs. The findings suggest that one route in particular that circumnavigates the Serengeti links the greatest number of small and medium sized entrepreneurial businesses to the largest labour force in the region. Furthermore, this route connects the most children to schools, provisions the greatest access to hospitals, and opens the most fertile crop and livestock production areas, and does not compromise the ecology and tourism revenue of the Serengeti. This route would improve Tanzania’s food security and self-reliance and would facilitate future infrastructure development which would not be possible if the road were to pass through the Serengeti. This case study provides a compelling example of how a detailed spatial analysis can balance the national objectives of poverty alleviation while

  13. In Silico study for diversing the molecular pathway of pigment formation: An alternative to manual coloring in cotton fibers.

    Directory of Open Access Journals (Sweden)

    Ammara eAhad

    2015-09-01

    Full Text Available Diversity of colors in flowers and fruits is largely due to anthocyanin pigments. The flavonoid/anthocyanin pathway has been most extensively studied. Dihydroflavonol 4-reductase (DFR is a vibrant enzyme of the flavonoid pathway which displays major impact on the formation of anthocyanins, flavan 3-ols and flavonols. The substrate specificity of the DFR was found to play a crucial role in determination of type of anthocyanidins. Altering the flavonoid/ anthocyanin pathway through genetic engineering to develop color of our own choice is an exciting subject of future research. In the present study, comparison among four DFR genes (Gossypium hirsutum, Iris × hollandica, Ang. DFRI and DFRII, sequence alignment for homology as well as protein modeling and docking is demonstrated. Estimation of catalytic sites, prediction of substrate preference and protein docking were the key features of this article. For specific substrate uptake, a proline rich region and positions 12 plus 26 along with other positions emphasizing the 26-amino acid residue region (132-157 was tested. Results showed that proline rich region position 12, 26 and 132-157 plays an important role in selective attachment of DFRs with respective substrates. Further, ‘Expasy ProtParam tool’ results showed that Iris × hollandica DFR amino acids (Asn 9: Asp 23 favorable for reducing DHQ and DHM thus accumulating delphinidin, while Gossypium hirsutum DFR has (Asn 13: Asp 21 hypothesized to consume DHK. Protein docking data showed that amino acid residues in above mentioned positions were just involved in attachment of DFR with substrate and had no role in specific substrate uptake.Advanced bioinformatics analysis has revealed that all above mentioned positions have role in substrate attachment. For substrate specificity, other residues region is involved. It will help in color manipulations in different plant species.

  14. Studies on the chemical conditions and microstructure in package 1 of alternative buffer materials project (ABM) in aespoe

    Energy Technology Data Exchange (ETDEWEB)

    Muurinen, A. (VTT Technical research Centre of Finland, Espoo (Finland))

    2010-02-15

    The chemical and microstructural properties of MX-80, Asha and Deponit bentonites and of Friedland Clay in package 1 of the ABM project in Aespoe HRL were studied after over two years of experiment. The concentration distribution of chloride and sulphate in different clays as a function of distance from the heater and in the reference bentonites, not used in the experiment, were determined. The concentration distributions of chloride were quite even. In Friedland clay and Asha the chloride concentrations in the clay decreased during the experiment while in MX-80 and Deponit the concentrations increased. Sulphate accumulated towards the hot end in the samples where the initial content of sulphate was high (Friedland Clay, MX-80, Deponit), while in Asha, where the initial sulphate concentration was low, such an accumulation did not occur. The cation exchange capacity in different clays was determined at different distances from the heater using the complex of copper(II) ion with trietylenetetramine [Cu(trien)]2+ as the index cation. The CEC of MX-80 and Deponit increased slightly close to the heater. In Asha there was some indication about the decrease of CEC close to the heater while in Friedland Clay there was small decreasing trend towards the heater and the CEC was generally slightly higher than in the reference sample. The pH measurements in the clays were performed with IrOx electrodes at a distance of 8 cm from the heater. The pH values were for Friedland Clay 6.5 - 6.6, for MX-80 6.6 - 6.8, for Asha 6.9 - 7.0 and for Deponit 6.6 - 6.9. The Eh measurements were performed with Pt and Au electrodes placed in the clays at 8 cm from the heater. The final values obtained after five months of measurement with Au and Pt electrodes were for Friedland Clay 17 mV and -231 mV, for MX-80 22 mV and -48 mV, for Asha 104 mV and 40 mV and for Deponit 76 mV and 75 mV, respectively. The water content and bulk density were measured at different distances from the heater; the dry

  15. Studies on the chemical conditions and microstructure in the reference bentonites of alternative buffer materials project (ABM) in Aespoe

    Energy Technology Data Exchange (ETDEWEB)

    Muurinen, A. (VTT Technical Research Centre of Finland, Espoo (Finland))

    2009-06-15

    The chemical and microstructural properties of some bentonites used in the ABM project in Aespoe HRL were studied in laboratory experiments. The aim was to obtain information about the materials before they were used in the field experiment and to test the research methods that will be used when the packages of the field experiment are retrieved. The bentonites of interest were MX-80, Deponit CAN, Asha 505 and Friedland Clay. The pH values in the compacted samples prepared from the clay powders and deionized water were about 8 for MX-80, 7 for Deponit and Asha, and 6.5 for Friedland clay. The Eh values in the compacted MX-80, Asha and Deponit samples varied between 100 mV and -100 mV, and in the Friedland clay from 0 mV to 200 mV. The total porosity, chloride porosity and the microstructure were studied in compacted samples prepared from MX-80, Deponit, Asha and Friedland Clay and equilibrated through filter plates with 0.1 M NaCl solution for 12.5 months in aerobic conditions. The dry densities of the samples were approximately 0.7, 1.0, 1.25 and 1.55 g/cm3. XRD and SAXS (Small Angle X-ray Scattering) were used to study the microstructure of the MX-80 and Deponit bentonites. It was obvious that the chloride porosity was lower than the water porosity in all the clays, which indicates the exclusion of anions caused by the negatively charged surfaces. In the XRD measurements on MX-80, Asha and Deponit, the measured basal spaces represented by the diffraction peaks were smaller than the theoretical one assuming a homogenous microstructure. This indicates that there was a substantial amount of water also in the pores, which were not seen by XRD. The SAXS data modelling which considered single discs and stacks of discs proposed that a large fraction of the clay should be considered as single platelets. The fraction of the single discs decreased with the increasing density of the sample. The number of layers in the stacks varied from 4 to 8. By combining the information

  16. A focus Group Study of Medical Students’ Views of an Integrated Complementary and Alternative Medicine (CAM Curriculum: Students Teaching Teachers

    Directory of Open Access Journals (Sweden)

    Désirée Lie, M.D

    2008-01-01

    Full Text Available Background: Student views of new curricula can shape training outcomes. This qualitative study elicited student opinions of CAM instruction to examine and distill best strategies.Methods: 49 second, third and fourth year students participated in focus groups using a predefined question route. Interviews were audio taped and transcribed.Results: Students successfully differentiated CAM curricula from other academic content and were supportive of a longitudinal integrated approach. They had positive disposition toward CAM use for themselves but this did not necessarily translate into patient recommendations. They agreed that goals of the CAM curriculum should center on awareness of patient use and evidence and information relevant to clinical practice. They advocated a case-based, hands-on, experiential strategy vs lectures. Students proposed greater institutional commitment to strengthen curricular effectiveness. The majority did not intend to practice CAM modalities but valued skills to assess them. Patient-centeredness was recognized. As training progressed, students exhibited a growing tendency to evaluate CAM efficacy, and therefore value, exclusively according to evidence.Conclusions: In-depth student input allowed examination of the effectiveness of a CAM curriculum,permitting improvement and assessment of program effectiveness.

  17. Financial viability study using a heat pump as an alternative to support solar collector for water heating in Southeastern Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Reis, Roberts Vinicius de Melo; Oliveira, Raphael Nunes; Machado, Luiz; Koury, Ricardo Nassau N. [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Dept. of Mechanical Engineering], E-mails: robertsreis@ufmg.br, luizm@demec.ufmg.br, koury@ufmg.br

    2010-07-01

    Along with related greenhouse effect environmental issues, constant problems changes in oil prices,make the use of solar energy an important renewable energy source. Brazil is a country which is privilege, considering the high rates of solar irradiation present throughout most of the entire national territory. Nevertheless, during certain times of the year, a solar energy deficit, leads solar systems to require electrical resistance support. The use of electrical resistance represents 23.5% of electric energy consumption and it presents a low residential energy efficiency. The purpose of this work is conducting a study of Brazilian States in the Southeastern region regarding the financial viability of replacing a resistive system combined with the use of solar collector and a heat pump. One such heat pump has been designed, constructed and tested experimentally. The average performance coefficient is equal to 2.10, a low value due to the use of a hermetic reciprocating compressor. Despite this low-moderate price coefficient of acquisition and installation of a heat pump, a return on investment in from 2.1 to 2.7 years can be expected. Whereas the equipment has a useful life of about 20 years, this period of return on investment is interesting. (author)

  18. Urban Floods in Lowlands—Levee Systems, Unplanned Urban Growth and River Restoration Alternative: A Case Study in Brazil

    Directory of Open Access Journals (Sweden)

    Marcelo Gomes Miguez

    2015-08-01

    Full Text Available The development of cities has always had a very close relation with water. However, cities directly impact land use patterns and greatly change natural landscapes, aggravating floods. Considering this situation, this paper intends to discuss lowland occupation and city sustainability in what regards urban stormwater management, fluvial space, and river restoration, aiming at minimizing flood risks and improving natural and built environment conditions. River plains tend to be attractive places for a city to grow. From ancient times, levees have been used to protect lowland areas along major watercourses to allow their occupation. However, urban rivers demand space for temporary flood storage. From a systemic point of view, levees along extensive river reaches act as canalization works, limiting river connectivity with flood plains, rising water levels, increasing overtopping risks and transferring floods downstream. Departing from this discussion, four case studies in the Iguaçu-Sarapuí River Basin, a lowland area of Rio de Janeiro State, Brazil, are used to compose a perspective in which the central point refers to the need of respecting watershed limits and giving space to rivers. Different aspects of low-lying city planning are discussed and analyzed concerning the integration of the built and natural environments.

  19. Blood Vessel Matrix Seeded with Cells: A Better Alternative for Abdominal Wall Reconstruction—A Long-Term Study

    Directory of Open Access Journals (Sweden)

    Maciej Nowacki

    2015-01-01

    Full Text Available Purpose. The aim of this study was to present abdominal wall reconstruction using a porcine vascular graft seeded with MSC (mesenchymal stem cells on rat model. Material and Methods. Abdominal wall defect was prepared in 21 Wistar rats. Acellular porcine-vascular grafts taken from aorta and prepared with Triton X were used. 14 aortic grafts were implanted in place, of which 7 grafts were seeded with rat MSC cells (Group I, and 7 were acellular grafts (Group II. As a control, 7 standard polypropylene meshes were used for defect augmentation (Group III. The assessment method was performed by HE and CD31 staining after 6 months. The mechanical properties have been investigated by Zwick&Roell Z0.5. Results. The strongest angiogenesis and lowest inflammatory response were observed in Group I. Average capillaries density was 2.75, 0.75, and 1.53 and inflammatory effect was 0.29, 1.39, and 2.72 for Groups I, II, and III, respectively. The means of mechanical properties were 12.74±1.48, 7.27±1.56, and 14.4±3.7 N/cm in Groups I and II and control, respectively. Conclusions. Cell-seeded grafts have better mechanical properties than acellular grafts but worse than polypropylene mesh. Cells improved mechanical and physiological properties of decellularized natural scaffolds.

  20. Carbon/PEEK composite materials as an alternative for stainless steel/titanium hip prosthesis: a finite element study.

    Science.gov (United States)

    Rezaei, Farshid; Hassani, Kamran; Solhjoei, Nosratollah; Karimi, Alireza

    2015-12-01

    Total hip replacement (THR) has been ranked within the most typical surgical processes in the world. The durability of the prosthesis and loosening of prosthesis are the main concerns that mostly reported after THR surgeries. In THR, the femoral prosthesis can be fixed by either cement or cementless methods in the patient's bones. In both procedures, the stability of the prosthesis in the hosted bone has a key asset in its long-term durability and performance. This study aimed to execute a comparative finite element simulation to assess the load transfer between the prosthesis, which is made of carbon/PEEK composite and stainless steel/titanium, and the femur bone. The mechanical behavior of the cortical bone was assumed as a linear transverse isotropic while the spongy bone was modeled like a linear isotropic material. The implants were made of stainless steel (316L) and titanium alloy as they are common materials for implants. The results showed that the carbon/PEEK composites provide a flatter load transfer from the upper body to the leg compared to the stainless steel/titanium prosthesis. Furthermore, the results showed that the von Mises stress, principal stress, and the strain in the carbon/PEEK composites prosthesis were significantly lower than that made of the stainless steel/titanium. The results also imply that the carbon/PEEK composites can be applied to introduce a new optimum design for femoral prosthesis with adjustable stiffness, which can decrease the stress shielding and interface stress. These findings will help clinicians and biomedical experts to increase their knowledge about the hip replacement.

  1. Alternative ozone metrics and daily mortality in Suzhou: the China Air Pollution and Health Effects Study (CAPES).

    Science.gov (United States)

    Yang, Chunxue; Yang, Haibing; Guo, Shu; Wang, Zongshuang; Xu, Xiaohui; Duan, Xiaoli; Kan, Haidong

    2012-06-01

    Controversy remains regarding the relationship between various metrics of ozone (O(3)) and mortality. In China, the largest developing country, there have been few studies investigating the acute effect of O(3) on death. We used three exposure metrics of O(3) (1-hour maximum, maximum 8-hour average and 24-hour average) to examine its short-term association with daily mortality in Suzhou, China. We used a Generalized Additive Model (GAM) with penalized splines to analyze the mortality, O(3), and covariate data. We examined the association by season, age group, sex and educational level. We found that the current level of O(3) in Suzhou is associated with death rates from all causes and cardiovascular diseases. Among various metrics of O(3), maximum 8-hour average and 1-hour maximum concentrations seem to be more strongly associated with increased mortality rate compared to 24-hour average concentrations. Using maximum 8-hour average, an inter-quartile range increase of 2-day average O(3) (lag 01) corresponds to 2.15% (95%CI, 0.36 to 3.93), 4.47% (95%CI, 1.43 to 7.51), -1.85% (95%CI, -6.91 to 3.22) increase in all-cause, cardiovascular, and respiratory mortality, respectively. The associations between O(3) and daily mortality appeared to be more evident in the cool season than in the warm season. In conclusion, maximum 8-hour average and 1-hour maximum concentrations of O(3) are associated with daily mortality in Suzhou. Our analyses strengthen the rationale for further limiting levels of O(3) pollution in the city. PMID:22521098

  2. The use of alternative pollutant metrics in time-series studies of ambient air pollution and respiratory emergency department visits.

    Science.gov (United States)

    Darrow, Lyndsey A; Klein, Mitchel; Sarnat, Jeremy A; Mulholland, James A; Strickland, Matthew J; Sarnat, Stefanie E; Russell, Armistead G; Tolbert, Paige E

    2011-01-01

    Various temporal metrics of daily pollution levels have been used to examine the relationships between air pollutants and acute health outcomes. However, daily metrics of the same pollutant have rarely been systematically compared within a study. In this analysis, we describe the variability of effect estimates attributable to the use of different temporal metrics of daily pollution levels. We obtained hourly measurements of ambient particulate matter (PM₂.₅), carbon monoxide (CO), nitrogen dioxide (NO₂), and ozone (O₃) from air monitoring networks in 20-county Atlanta for the time period 1993-2004. For each pollutant, we created (1) a daily 1-h maximum; (2) a 24-h average; (3) a commute average; (4) a daytime average; (5) a nighttime average; and (6) a daily 8-h maximum (only for O₃). Using Poisson generalized linear models, we examined associations between daily counts of respiratory emergency department visits and the previous day's pollutant metrics. Variability was greatest across O₃ metrics, with the 8-h maximum, 1-h maximum, and daytime metrics yielding strong positive associations and the nighttime O₃ metric yielding a negative association (likely reflecting confounding by air pollutants oxidized by O₃). With the exception of daytime metric, all of the CO and NO₂ metrics were positively associated with respiratory emergency department visits. Differences in observed associations with respiratory emergency room visits among temporal metrics of the same pollutant were influenced by the diurnal patterns of the pollutant, spatial representativeness of the metrics, and correlation between each metric and copollutant concentrations. Overall, the use of metrics based on the US National Ambient Air Quality Standards (for example, the use of a daily 8-h maximum O₃ as opposed to a 24-h average metric) was supported by this analysis. Comparative analysis of temporal metrics also provided insight into underlying relationships between specific air

  3. Is "Active Surveillance" an Acceptable Alternative?: A Qualitative Study of Couples' Decision Making about Early-Stage, Localized Prostate Cancer.

    Science.gov (United States)

    Le, Chi L; McFall, Stephanie L; Byrd, Theresa L; Volk, Robert J; Cantor, Scott B; Kuban, Deborah A; Mullen, Patricia Dolan

    2016-01-01

    The objective of our study was to describe decision making by men and their partners regarding active surveillance (AS) or treatment for early-stage, localized prostate cancer. Fifteen couples were recruited from a cancer center multispecialty clinic, which gave full information about all options, including AS. Data were collected via individual, semi-structured telephone interviews. Most patients were white, non-Hispanic, had private insurance, had completed at least some college, and were aged 49-72 years. Ten chose AS. All partners were female, and couples reported strong marital satisfaction and cohesion. All couples described similar sequences of a highly emotional initial reaction and desire to be rid of the cancer, information seeking, and decision making. The choice of AS was built on a nuanced evaluation of the man's condition in which the couple differentiated prostate cancer from other cancers and early stage from later stages, wanted to avoid/delay side effects, and trusted the AS protocol to identify negative changes in time for successful treatment. Treated couples continued to want immediate treatment to remove the cancer. We concluded that having a partner's support for AS may help a man feel more comfortable with choosing and adhering to AS. Using decision aids that address both a man's and his partner's concerns regarding AS may increase its acceptability. Our research shows that some patients want to and do involve their partners in the decision-making process. Ethical issues are related to the tension between desire for partner involvement and the importance of the patient as autonomous decision-maker. The extended period of decision making, particularly for AS, is also an ethical issue that requires additional support for patients and couples in the making of fully informed choices that includes AS.

  4. Alternative ways of using field-based estimates to calibrate ecosystem models and their implications for carbon cycle studies

    Science.gov (United States)

    He, Yujie; Zhuang, Qianlai; McGuire, David; Liu, Yaling; Chen, Min

    2013-01-01

    Model-data fusion is a process in which field observations are used to constrain model parameters. How observations are used to constrain parameters has a direct impact on the carbon cycle dynamics simulated by ecosystem models. In this study, we present an evaluation of several options for the use of observations in modeling regional carbon dynamics and explore the implications of those options. We calibrated the Terrestrial Ecosystem Model on a hierarchy of three vegetation classification levels for the Alaskan boreal forest: species level, plant-functional-type level (PFT level), and biome level, and we examined the differences in simulated carbon dynamics. Species-specific field-based estimates were directly used to parameterize the model for species-level simulations, while weighted averages based on species percent cover were used to generate estimates for PFT- and biome-level model parameterization. We found that calibrated key ecosystem process parameters differed substantially among species and overlapped for species that are categorized into different PFTs. Our analysis of parameter sets suggests that the PFT-level parameterizations primarily reflected the dominant species and that functional information of some species were lost from the PFT-level parameterizations. The biome-level parameterization was primarily representative of the needleleaf PFT and lost information on broadleaf species or PFT function. Our results indicate that PFT-level simulations may be potentially representative of the performance of species-level simulations while biome-level simulations may result in biased estimates. Improved theoretical and empirical justifications for grouping species into PFTs or biomes are needed to adequately represent the dynamics of ecosystem functioning and structure.

  5. Alternative Dose for Choroidal Melanoma Treated With an Iodine-125 Radioactive Plaque: A Single-Institution Retrospective Study

    International Nuclear Information System (INIS)

    Purpose: The Collaborative Ocular Melanoma Study (COMS) established iodine-125 plaque brachytherapy as an accepted standard treatment for medium-size choroidal melanoma. In the COMS, the prescription dose was 85 Gy. This is a retrospective review of our outcomes in patients treated with lower doses than those used in the COMS. Methods and Materials: From 1990 to 2004, 62 patients were treated with iodine-125 plaque brachytherapy for choroidal melanoma. COMS eye plaques were used with dose prescribed to the apex of the tumor. The median and average dose rates at the tumor apex were 63.5 cGy/h and 62.7 cGy/h, respectively. The median and average total doses were 63.0 Gy and 62.5 Gy (range, 56-69 Gy), respectively. The median and mean durations of implant were 100.0 hours and 101.1 hours (range, 71-165 hours). Results: Median follow-up time was 58.2 months. The 5-year outcomes including overall survival, disease-free survival, cause-specific survival, local failure, secondary enucleation rate, and visual acuity (VA) <20/200 were estimated using the Kaplan-Meier method. Overall, there were 7 local failures, 4 distant failures, and 10 secondary enucleations (6 due to local failure and 4 due to treatment complications). Univariate analysis was performed to identify significant prognostic factors associated with disease-free survival (baseline VA in tumor eye, tumor shape), cause-specific survival (diabetic retinopathy), local failure (none found), secondary enucleation rate (diabetic retinopathy, basal tumor dimension) and VA <20/200 (diabetic retinopathy, tumor shape, age, retinal detachment, treatment depth, and history of vision-limiting condition). Conclusions: Our survival and local control outcomes are comparable to those of the COMS. However, VA at 5 years seems to be better. Lower doses of radiation could potentially lead to better visual outcomes.

  6. Using sequence data to identify alternative routes and risk of infection: a case-study of campylobacter in Scotland

    Directory of Open Access Journals (Sweden)

    Bessell Paul R

    2012-04-01

    rapidly increasing capacity to conduct genetic typing of pathogens makes such traced epidemiological analysis more accessible and has the potential to substantially enhance epidemiological risk factor studies.

  7. Seeking an Alternative Modality to the Management of Nigeria's Fertilizer Subsidy Scheme-An Empirical Approach to the Case Study of Ondo State (1976-1996

    Directory of Open Access Journals (Sweden)

    Victor O. Asekunowo

    2010-01-01

    Full Text Available Problem statement: The objective of Nigeria’s fertilizer subsidy scheme was to make inorganic fertilizers readily available to farmers at affordable prices in order to boost food production in the country. Shortly into the scheme, farmers complained that fertilizers were not received at the time of need and in sufficient quantities. Approach: Using Ondo State, Nigeria as a case study, to determine; inter alia, if the farmers’ complaints were founded and if so, to design alternative ways of administering the scheme such that the lofty goals for which it was established could be realized. Methodology: Primary data were collected from 596 farmers randomly selected from the state. Secondary data were collected from purposively selected NAFCON, AISC, ADP, FPDD (now FFD and a published book source. The primary data were analyzed with the use of descriptive statistics such as percentages and means. The secondary data were analyzed with the use of OLS and TLS regression methods. Results: The descriptive analyses showed that farmers in Ondo State did not receive their fertilizer supplies in sufficient quantities and at the time of need, despite the fact that supply surpassed adoption (demand for most years of the study period. The inferential analyses showed that a subsidy introduced into NAFCON and other producing firms’ production processes would engender increased output and induce fertilizer prices to fall in Ondo State. Conclusion: These results showed that farmers in Ondo State did not receive their fertilizer supplies at the time of need and in sufficient quantities due to leakages and diversion of the substance from the vast bureaucratic distribution channels. As an alternative, if subsidy was administered through the producing firms’ production processes, output of fertilizers would have increased making the market supply curve of fertilizers to shift to the right. This would have also caused the price of fertilizer to

  8. Modeling the influence of alternative forest management scenarios on wood production and carbon storage: A case study in the Mediterranean region.

    Science.gov (United States)

    Bottalico, Francesca; Pesola, Lucia; Vizzarri, Matteo; Antonello, Leonardo; Barbati, Anna; Chirici, Gherardo; Corona, Piermaria; Cullotta, Sebastiano; Garfì, Vittorio; Giannico, Vincenzo; Lafortezza, Raffaele; Lombardi, Fabio; Marchetti, Marco; Nocentini, Susanna; Riccioli, Francesco; Travaglini, Davide; Sallustio, Lorenzo

    2016-01-01

    Forest ecosystems are fundamental for the terrestrial biosphere as they deliver multiple essential ecosystem services (ES). In environmental management, understanding ES distribution and interactions and assessing the economic value of forest ES represent future challenges. In this study, we developed a spatially explicit method based on a multi-scale approach (MiMoSe-Multiscale Mapping of ecoSystem services) to assess the current and future potential of a given forest area to provide ES. To do this we modified and improved the InVEST model in order to adapt input data and simulations to the context of Mediterranean forest ecosystems. Specifically, we integrated a GIS-based model, scenario model, and economic valuation to investigate two ES (wood production and carbon sequestration) and their trade-offs in a test area located in Molise region (Central Italy). Spatial information and trade-off analyses were used to assess the influence of alternative forest management scenarios on investigated services. Scenario A was designed to describe the current Business as Usual approach. Two alternative scenarios were designed to describe management approaches oriented towards nature protection (scenario B) or wood production (scenario C) and compared to scenario A. Management scenarios were simulated at the scale of forest management units over a 20-year time period. Our results show that forest management influenced ES provision and associated benefits at the regional scale. In the test area, the Total Ecosystem Services Value of the investigated ES increases 85% in scenario B and decreases 82% in scenario C, when compared to scenario A. Our study contributes to the ongoing debate about trade-offs and synergies between carbon sequestration and wood production benefits associated with socio-ecological systems. The MiMoSe approach can be replicated in other contexts with similar characteristics, thus providing a useful basis for the projection of benefits from forest

  9. Isolation of RNA from milk somatic cells as an alternative to biopsies of mammary tissue for nutrigenomic studies in dairy ewes.

    Science.gov (United States)

    Toral, P G; Hervás, G; Suárez-Vega, A; Arranz, J J; Frutos, P

    2016-10-01

    Nutrigenomic studies of mammary lipogenesis in ruminants often rely on the use of mammary tissue (MT) collected either by biopsy or at slaughter. However, isolating RNA from milk would be a useful and cost-effective technique that may avoid distress to the animal and facilitate the collection of samples in time series experiments. This assay was therefore conducted to test the hypothesis that RNA extracted from milk somatic cells (MSC) in dairy sheep would be a feasible alternative to the performance of MT biopsies for nutrigenomic analyses. To meet this objective, 8 lactating Assaf ewes were divided in 2 groups and offered a total mixed ration without supplementation (control) or supplemented with 2.4% dry matter of fish oil, which was known not only to elicit milk fat depression but also to downregulate the expression of some candidate genes involved in mammary lipogenesis. Total RNA was extracted from MSC and biopsied MT to examine whether the potential changes in the abundance of transcripts was similarly detected with both RNA sources. Milk fatty acid profile was also analyzed by gas chromatography, and variations in mRNA abundance were determined by reverse transcription quantitative PCR. Values of RNA integrity number were always ≥7.7. The expected and designed decrease of milk fat concentration with fish oil (-29%), was associated with a lower transcript abundance of genes coding for enzymes involved in fatty acid activation (ACSS1), de novo synthesis (ACACA and FASN), uptake from plasma lipids (LPL), and esterification of fatty acids to glycerol (LPIN1), as well as of a transcription factor that may regulate their expression (INSIG1). Stable mRNA levels were showed in other candidate genes, such as FABP3, GPAT4, or SCD. Changes due to the dietary treatment were similarly detected with both RNA sources (MSC and MT biopsies), which supports the initial hypothesis and would validate the use of milk as an alternative RNA source for nutrigenomic analyses in

  10. Compatibility study of a low-calorie cocoa butter alternative%一种低热代可可脂的相容性研究

    Institute of Scientific and Technical Information of China (English)

    宋志华; 黄健花; 韩璐; 金青哲; 王兴国

    2015-01-01

    采用等温曲线和ΔSFC 曲线分析法,研究了自制短长碳链低热代可可脂(LCSL)与市售可可脂(CB)、非月桂酸类代可可脂(CBR)、月桂酸类代可可脂(CBS)、类可可脂(CBE)产品的相容性,结果表明:LCSL 与市售产品在低温下的相容性较好,其中与 CBS 的相容性最好,温度低于20℃时 LCSL 与 CBS 可任何比例相容;LCSL 适合完全取代 CB 用于生产糖果或巧克力制品,且在配方中需控制 CB 含量低于5%。%The compatibility of the blends of a low–calorie cocoa butter alternative(LCSL)prepared in laboratory and commercially cocoa butter(CB),non–lauric cocoa butter replacers(CBR), lauric cocoa butter substitute(CBS)and cocoa butter equivalents(CBE)were studied. The solid fat isothermal curve and solid fat difference(ΔSFC)curve indicated the good compatibility of LCSL with CB or CB alternatives at lower temperature. The mixture of LCSL and CBS was the best one. Any proportion of compatibility between LCSL and CBS was detected when the temperature was lower than 20 ℃ . LCSL was suitable for replacing CB completely in chocolate,chocolate coating and other confectionery products,and the content of CB should be lower than 5%.

  11. Expression of alternative oxidase in tomato

    Energy Technology Data Exchange (ETDEWEB)

    Kakefuda, M.; McIntosh, L. (Michigan State Univ., East Lansing (USA))

    1990-05-01

    Tomato fruit ripening is characterized by an increase in ethylene biosynthesis, a burst in respiration (i.e. the climacteric), fruit softening and pigmentation. As whole tomatoes ripened from mature green to red, there was an increase in the alternative oxidase capacity. Aging pink tomato slices for 24 and 48 hrs also showed an increase of alternative oxidase and cytochrome oxidase capacities. Monoclonal antibodies prepared to the Sauromatum guttatum alternative oxidase were used to follow the appearance of alternative oxidase in tomato fruits. There is a corresponding increase in a 36kDa protein with an increase in alternative oxidase capacity. Effects of ethylene and norbornadiene on alternative oxidase capacity were also studied. We are using an alternative oxidase cDNA clone from potato to study the expression of mRNA in ripening and wounded tomatoes to determine if the gene is transcriptionally regulated.

  12. Alternative tsunami models

    Energy Technology Data Exchange (ETDEWEB)

    Tan, A; Lyatskaya, I [Department of Physics, Alabama A and M University, Normal, AL 35762 (United States)], E-mail: arjun.tan@aamu.edu

    2009-01-15

    The interesting papers by Margaritondo (2005 Eur. J. Phys. 26 401) and by Helene and Yamashita (2006 Eur. J. Phys. 27 855) analysed the great Indian Ocean tsunami of 2004 using a simple one-dimensional canal wave model, which was appropriate for undergraduate students in physics and related fields of discipline. In this paper, two additional, easily understandable models, suitable for the same level of readership, are proposed: one, a two-dimensional model in flat space, and two, the same on a spherical surface. The models are used to study the tsunami produced by the central Kuril earthquake of November 2006. It is shown that the two alternative models, especially the latter one, give better representations of the wave amplitude, especially at far-flung locations. The latter model further demonstrates the enhancing effect on the amplitude due to the curvature of the Earth for far-reaching tsunami propagation.

  13. On an Alternative Cosmology

    CERN Document Server

    Vankov, A

    1998-01-01

    The suggested alternative cosmology is based on the idea of barion symmetric universe, in which our home universe is a representative of multitude of typical matter and antimatter universes. This alternative concept gives a physically reasonable explanation of all major problems of the Standard Cosmological Model. Classification Code MSC: Cosmology 524.8 Key words: standard cosmological model, alternative cosmology, barionic symmetry, typical universe, quasars, cosmic rays.

  14. Polyphase alternating codes

    CERN Document Server

    Markkanen, Markku

    2007-01-01

    This work introduces a method for constructing polyphase alternating codes in which the length of a code transmission cycle can be $p^m$ or $p-1$, where $p$ is a prime number and $m$ is a positive integer. The relevant properties leading to the construction alternating codes and the algorithm for generating alternating codes is described. Examples of all practical and some not that practical polyphase code lengths are given.

  15. Alternative Solar Indices

    Energy Technology Data Exchange (ETDEWEB)

    Lantz, L.J.

    1980-07-01

    Possible alternative Solar Indices which could either be a perturbation from the currently defined Solar Index or possible indices based on current technologies for other media markets are discussed. An overview is given of the current project, including the logic that was utilized in defining its current structure and then alternative indices and definitions are presented and finally, recommendations are made for adopting alternative indices.

  16. Complex Alternative Splicing

    OpenAIRE

    Park, Jung Woo; Graveley, Brenton R.

    2007-01-01

    Alternative splicing is a powerful means of controlling gene expression and increasing protein diversity. Most genes express a limited number of mRNA isoforms, but there are several examples of genes that use alternative splicing to generate hundreds, thousands, and even tens of thousands of isoforms. Collectively such genes are considered to undergo complex alternative splicing. The best example is the Drosophila Down syndrome cell adhesion molecule (Dscam) gene, which can generate 38,016 is...

  17. A Preliminary Study on the Conceptual Design of Thorium/Uranium Mixed Nuclear Fuel for the Alternative of Burnable Poison in Commercial Pressurized Water Reactor

    International Nuclear Information System (INIS)

    Thorium has higher neutron absorption cross section than that of U-238. Thus, the thorium mixed uranium oxide nuclear fuel can reduce the initial excessive reactivity and the long-live radio-wastes with increasing the fuel utilization efficiency. In this study, a preliminary study on the application of the thorium/uranium mixed fuel is performed for the alternative of the PLUS7 fuel assembly which includes burnable poison. A conceptual design without geometrical change is proposed and the reactor characteristics are analyzed. In this study, a fuel assembly using the uranium/thorium mixed fuel was designed to substitute the assembly which includes burnable poison. The reactor characteristics, which are kinf, power distribution and plutonium production rate, were evaluated and the results are compared with the E1 assembly which is used in the OPR1000 reactor. The results show that the proposed design can efficiently reduce the excessive reactivity, peak power, and plutonium production with increasing the fuel utilization period

  18. Complementary and Alternative Medicine Use and Its Association with Quality of Life among Cancer Patients Receiving Chemotherapy in Ethiopia: A Cross-Sectional Study.

    Science.gov (United States)

    Erku, Daniel Asfaw

    2016-01-01

    Background. Today, complementary and alternative medicine (CAM) use is being routinely practiced by cancer patients worldwide. This study aimed at examining the prevalence of CAM use in patients with cancer and comparing the quality of life (QoL) in CAM users and nonusers. Methods. A cross-sectional study was employed on 195 cancer patients receiving chemotherapy at Gondar University Referral Hospital (GURH) chemotherapy center. Interviewer-administered questionnaires were used and the collected data were analyzed by the Statistical Package for the Social Sciences (SPSS) software version 21.0 for Windows. Results. 154 (79%) patients were found to be users of CAM. Educational status, average monthly income, disease stage, and comorbidity were strong predictors of use of CAM. The most commonly utilized types of CAM were traditional herbal based medicine (72.1%) and only 20.8% of patients discuss with their doctors CAM use. No significant difference was found in QoL between CAM users and nonusers except in financial difficulties (p = 0.020). Conclusions. This study revealed a high rate of CAM use with very low disclosure rate to their health care providers. Health care providers should be open to discuss the use of CAM with their patients as it will lead to better health outcome. PMID:27433182

  19. Experimental and analytical study of cryogenic propellant boiloff to develop and verify alternate pressurization concepts for Space Shuttle external tank using a scaled down tank

    Science.gov (United States)

    Akyuzlu, K. M.; Jones, S.; Meredith, T.

    1993-01-01

    Self pressurization by propellant boiloff is experimentally studied as an alternate pressurization concept for the Space Shuttle external tank (ET). The experimental setup used in the study is an open flow system which is composed of a variable area test tank and a recovery tank. The vacuum jacketed test tank is geometrically similar to the external LOx tank for the Space Shuttle. It is equipped with instrumentation to measure the temperature and pressure histories within the liquid and vapor, and viewports to accommodate visual observations and Laser-Doppler Anemometry measurements of fluid velocities. A set of experiments were conducted using liquid Nitrogen to determine the temperature stratification in the liquid and vapor, and pressure histories of the vapor during sudden and continuous depressurization for various different boundary and initial conditions. The study also includes the development and calibration of a computer model to simulate the experiments. This model is a one-dimensional, multi-node type which assumes the liquid and the vapor to be under non-equilibrium conditions during the depressurization. It has been tested for a limited number of cases. The preliminary results indicate that the accuracy of the simulations is determined by the accuracy of the heat transfer coefficients for the vapor and the liquid at the interface which are taken to be the calibration parameters in the present model.

  20. Blood spots as an alternative to whole blood collection and the effect of a small monetary incentive to increase participation in genetic association studies

    Directory of Open Access Journals (Sweden)

    Ringer Danny

    2009-11-01

    Full Text Available Abstract Background Collection of buccal cells from saliva for DNA extraction offers a less invasive and convenient alternative to venipuncture blood collection that may increase participation in genetic epidemiologic studies. However, dried blood spot collection, which is also a convenient method, offers a means of collecting peripheral blood samples from which analytes in addition to DNA can be obtained. Methods To determine if offering blood spot collection would increase participation in genetic epidemiologic studies, we conducted a study of collecting dried blood spot cards by mail from a sample of female cancer cases (n = 134 and controls (n = 256 who were previously selected for a breast cancer genetics study and declined to provide a venipuncture blood sample. Participants were also randomized to receive either a $2.00 bill or no incentive with the blood spot collection kits. Results The average time between the venipuncture sample refusal and recruitment for the blood spot collection was 4.4 years. Thirty-seven percent of cases and 28% of controls provided a dried blood spot card. While the incentive was not associated with participation among controls (29% for $2.00 incentive vs. 26% for no incentive, p = 0.6, it was significantly associated with participation among the breast cancer cases (48% vs. 27%, respectively, p = 0.01. There did not appear to be any bias in response since no differences between cases and controls and incentive groups were observed when examining several demographic, work history and radiation exposure variables. Conclusion This study demonstrates that collection of dried blood spot cards in addition to venipuncture blood samples may be a feasible method to increase participation in genetic case-control studies.

  1. Optical studies of carriers’ vertical transport in the alternately-strained ZnS{sub 0.4}Se{sub 0.6}/CdSe superlattice

    Energy Technology Data Exchange (ETDEWEB)

    Evropeytsev, E. A., E-mail: evropeitsev@beam.ioffe.ru; Sorokin, S. V.; Gronin, S. V.; Sedova, I. V.; Klimko, G. V.; Ivanov, S. V.; Toropov, A. A. [Russian Academy of Sciences, Ioffe Physical-Technical Institute (Russian Federation)

    2015-03-15

    We present the results of theoretical modelling and experimental optical studies of the alternatively-strained CdSe/ZnS{sub y}Se{sub 1−y} (y = 0.4) superlattice (SL) with effective band-gap E{sub g}{sup eff} ∼ 2.580 eV and a thickness of ∼300 nm, which was grown by molecular-beam epitaxy on a GaAs substrate. The thicknesses and composition of the layers of the superlattice are determined on the basis of the SL minibands parameters calculated implying both full lattice matching of the SL as a whole to a GaAs substrate and high efficiency of photoexcited carriers transport along the growth axis. Photoluminescence studies of the transport properties of the structure (including a superlattice with one enlarged quantum well) show that the characteristic time of the diffusion of charge carriers at 300 K is shorter than the times defined by recombination processes. Such superlattices seem to be promising for the formation of a wide-gap photoactive region in a multijunction solar cell, which includes both III–V and II–VI compounds.

  2. Piped water consumption in Ghana: A case study of temporal and spatial patterns of clean water demand relative to alternative water sources in rural small towns.

    Science.gov (United States)

    Kulinkina, Alexandra V; Kosinski, Karen C; Liss, Alexander; Adjei, Michael N; Ayamgah, Gilbert A; Webb, Patrick; Gute, David M; Plummer, Jeanine D; Naumova, Elena N

    2016-07-15

    Continuous access to adequate quantities of safe water is essential for human health and socioeconomic development. Piped water systems (PWSs) are an increasingly common type of water supply in rural African small towns. We assessed temporal and spatial patterns in water consumption from public standpipes of four PWSs in Ghana in order to assess clean water demand relative to other available water sources. Low water consumption was evident in all study towns, which manifested temporally and spatially. Temporal variability in water consumption that is negatively correlated with rainfall is an indicator of rainwater preference when it is available. Furthermore, our findings show that standpipes in close proximity to alternative water sources such as streams and hand-dug wells suffer further reductions in water consumption. Qualitative data suggest that consumer demand in the study towns appears to be driven more by water quantity, accessibility, and perceived aesthetic water quality, as compared to microbiological water quality or price. In settings with chronic under-utilization of improved water sources, increasing water demand through household connections, improving water quality with respect to taste and appropriateness for laundry, and educating residents about health benefits of using piped water should be prioritized. Continued consumer demand and sufficient revenue generation are important attributes of a water service that ensure its function over time. Our findings suggest that analyzing water consumption of existing metered PWSs in combination with qualitative approaches may enable more efficient planning of community-based water supplies and support sustainable development.

  3. Piped water consumption in Ghana: A case study of temporal and spatial patterns of clean water demand relative to alternative water sources in rural small towns.

    Science.gov (United States)

    Kulinkina, Alexandra V; Kosinski, Karen C; Liss, Alexander; Adjei, Michael N; Ayamgah, Gilbert A; Webb, Patrick; Gute, David M; Plummer, Jeanine D; Naumova, Elena N

    2016-07-15

    Continuous access to adequate quantities of safe water is essential for human health and socioeconomic development. Piped water systems (PWSs) are an increasingly common type of water supply in rural African small towns. We assessed temporal and spatial patterns in water consumption from public standpipes of four PWSs in Ghana in order to assess clean water demand relative to other available water sources. Low water consumption was evident in all study towns, which manifested temporally and spatially. Temporal variability in water consumption that is negatively correlated with rainfall is an indicator of rainwater preference when it is available. Furthermore, our findings show that standpipes in close proximity to alternative water sources such as streams and hand-dug wells suffer further reductions in water consumption. Qualitative data suggest that consumer demand in the study towns appears to be driven more by water quantity, accessibility, and perceived aesthetic water quality, as compared to microbiological water quality or price. In settings with chronic under-utilization of improved water sources, increasing water demand through household connections, improving water quality with respect to taste and appropriateness for laundry, and educating residents about health benefits of using piped water should be prioritized. Continued consumer demand and sufficient revenue generation are important attributes of a water service that ensure its function over time. Our findings suggest that analyzing water consumption of existing metered PWSs in combination with qualitative approaches may enable more efficient planning of community-based water supplies and support sustainable development. PMID:27070382

  4. A parametric study on the emissions from an HCCI alternative combustion engine resulting from the auto-ignition of primary reference fuels

    Energy Technology Data Exchange (ETDEWEB)

    Machrafi, Hatim; Cavadias, Simeon; Amouroux, Jacques [UPMC Universite Paris 06, LGPPTS, Ecole Nationale Superieure de Chimie de Paris, 11, rue de Pierre et Marie Curie, 75005 Paris (France)

    2008-08-15

    The homogeneous charge compression ignition is an alternative combustion technology that can reduce automobile pollution, provided that the exhaust emission can be controlled. A parametric study can be useful in order to gain more understanding in the emission reduction possibilities via this new combustion technology. For this purpose, the inlet temperature, the equivalence ratio and the compression ratio are changed, respectively, from 30 to 70{sup o}C, 0.28 to 0.41 and 6 to 14. Also the diluting, thermal and chemical effects of exhaust gas recirculation were studied. The emission of CO, CO{sub 2}, O{sub 2} and hydrocarbons has been measured using primary reference fuels. It appears that an increase in the inlet temperature, the EGR temperature, the equivalence ratio and the compression ratio results into a decrease of the emissions of CO and the hydrocarbons of up to 75%. The emission of CO{sub 2} increased, however, by 50%. The chemical parameters showed more complicated effects, resulting into a decrease or increase of the emissions, depending on whether the overall reactivity increased or not. If the reactivity increased, generally, the emissions of CO and hydrocarbons increased, while that of CO{sub 2} increased. The increase of CO{sub 2} emissions could be compensated by altering the compression ratio and the EGR parameters, making it possible to control the emission of the HCCI engine. (author)

  5. Use of ostrich faeces as alternative inoculum to caecal content to study the in vitro digestibility of alfalfa (green, dehydrated and hay

    Directory of Open Access Journals (Sweden)

    C. Di Meo

    2010-04-01

    Full Text Available In order to find an alternative source of inoculum to caecal content for studying the in vitro feed digestibility in domesticated ostriches, caecal content and faeces of 4 male birds were used as inocula for an in vitro gas production trial. Three alfalfa (hay, AH; green , GA; dehydrated, DA were used as substrates. Caecal content and faeces, diluted respectively 1:2 (CI and 1:4 (FI with an anaerobic medium and were used as inocula. Gas production was recorded 22 times up to 120 h of incubation and fermentation characteristics (e.g. degraded organic matter, OMd; potential gas production, A; maximum fermentation rate, Rmax; volatile fatty acid, VFA were studied by inoculum and substrate. CI showed a higher OMd (67.90 vs 64.60 %, respectively for CI and FI, P < 0.01 but lower A (200.6 vs 212.6 ml/g, respectively for CI and FI, P < 0.01 and Rmax (5.94 vs 6.56 ml/h, respectively for CI and FI, P < 0.05 than FI. No differences were found in tVFA production. The significant higher value of branched chain proportion [(isovaleric + isobutyrate/tVFA] for CI (0.039 vs 0.032 respectively for CI and FI, P < 0.05 indicate a higher degradation protein for this inoculum.

  6. Alternative Devices for Taking Insulin

    Science.gov (United States)

    ... KB). Alternate Language URL Alternative Devices for Taking Insulin Page Content On this page: What alternative devices ... the skin. [ Top ] What alternative devices for taking insulin are available? Insulin pens provide a convenient, easy- ...

  7. Alternative health insurance schemes

    DEFF Research Database (Denmark)

    Keiding, Hans; Hansen, Bodil O.

    2002-01-01

    In this paper, we present a simple model of health insurance with asymmetric information, where we compare two alternative ways of organizing the insurance market. Either as a competitive insurance market, where some risks remain uninsured, or as a compulsory scheme, where however, the level...... competitive insurance; this situation turns out to be at least as good as either of the alternatives...

  8. GLOBAL TRENDS OF ALTERNATIVE INVESTMENTS

    Directory of Open Access Journals (Sweden)

    Ivan LUCHIAN

    2016-08-01

    Full Text Available An alternative investment is an investment product other than the traditional investments of stocks, bonds, cash, or property. The term is a relatively loose one and includes tangible assets such as art, wine, antiques, coins, or stamps and some financial assets such as commodities, hedge funds, venture capital,and others. At the moment it was created a global industry opportunities for making investments in nontraditional form. The aim of this paper consists in demonstrating the possibilities of these investments. For this have been studied related main international markets, a fter then deducted world dominant trends. This article is concerned to present some details of alternative investments global market.

  9. Continuous versus intermittent tamoxifen versus intermittent/alternated tamoxifen and medroxyprogesterone acetate as first line endocrine treatment in advanced breast cancer : An EORTC phase III study (10863)

    NARCIS (Netherlands)

    Beex, L.; Rose, C.; Mouridsen, H.; Jassem, J.; Nooij, M.; Estape, J.; Paridaens, R.; Piccart, M.; Gorlia, T.; Lardenoije, S.; Baila, L.

    2006-01-01

    Background: Continuous ligand depletion of endocrine responsive tumours may enhance resistance to therapy. Intermittent treatment with tamoxifen (T) was considered to mimic (incomplete) ligand depletion and reintroduction. Furthermore it was postulated that alternating tamoxifen with a non-cross res

  10. Continuous versus intermittent tamoxifen versus intermittent/alternated tamoxifen and medroxyprogesterone acetate as first line endocrine treatment in advanced breast cancer: an EORTC phase III study (10863).

    NARCIS (Netherlands)

    Beex, L.V.A.M.; Rose, C.; Mouridsen, H.; Jassem, J.; Nooij, M.; Estape, J.; Paridaens, R.; Piccart, M.; Gorlia, T.; Lardenoije, S.; Baila, L.

    2006-01-01

    BACKGROUND: Continuous ligand depletion of endocrine responsive tumours may enhance resistance to therapy. Intermittent treatment with tamoxifen (T) was considered to mimic (incomplete) ligand depletion and reintroduction. Furthermore it was postulated that alternating tamoxifen with a non-cross res

  11. A Simple Alternative to Grading

    Science.gov (United States)

    Potts, Glenda

    2010-01-01

    In this article, the author investigates whether an alternative grading system (contract grading) would yield the same final grades as traditional grading (letter grading), and whether or not it would be accepted by students. The author states that this study demonstrated that contract grading was widely, and for the most part, enthusiastically…

  12. Ash Properties of Alternative Biomass

    DEFF Research Database (Denmark)

    Capablo, Joaquin; Jensen, Peter Arendt; Pedersen, Kim Hougaard;

    2009-01-01

    The ash behavior during suspension firing of 12 alternative solid biofuels, such as pectin waste, mash from a beer brewery, or waste from cigarette production have been studied and compared to wood and straw ash behavior. Laboratory suspension firing tests were performed on an entrained flow...

  13. Nuclear energy: a sensible alternative

    International Nuclear Information System (INIS)

    This book presents in-depth articles on the main issues affecting the use and usefulness of nuclear energy for peaceful domestic purposes. Topics considered include energy futures (a world study), energy demand-energy supplies, an energy-deficient society, energy shortages, the economics of light water reactors (LWRs), fast breeder reactor economics, international cooperation in the nuclear field, nuclear recycling (costs, savings, safeguards), alternative fuels, alternative fuel cycles, alternative reactors, the nuclear weapons proliferation issue, paths to a world with more reliable nuclear safeguards, the homemade bomb issue, LWR risk assessment, accident analysis and risk assessment, the waste disposal risk, radon problems, health effects of low-level radiation, routine releases of radioactivity, plutonium toxicity, and the Price-Anderson Act

  14. A study on synthesis of energy fuel from waste plastic and assessment of its potential as an alternative fuel for diesel engines.

    Science.gov (United States)

    Kaimal, Viswanath K; Vijayabalan, P

    2016-05-01

    The demand for plastic is ever increasing and has produced a huge amount of plastic waste. The management and disposal of plastic waste have become a major concern, especially in developing cities. The idea of waste to energy recovery is one of the promising techniques used for managing the waste plastic. This paper assesses the potential of using Waste Plastic Oil (WPO), synthesized using pyrolysis of waste plastic, as an alternative for diesel fuel. In this research work, the performance and emission characteristics of a single cylinder diesel engine fuelled with WPO and its blends with diesel are studied. In addition to neat plastic oil, three blends (PO25, PO50 and PO75) were prepared on a volumetric basis and the engine was able to run on neat plastic oil. Brake thermal efficiency of blends was lower compared to diesel, but PO25 showed similar performance to that of diesel. The emissions were reduced considerably while using blends when compared to neat plastic oil. The smoke and NOX were reduced by 22% and 17.8% respectively for PO25 than that of plastic oil. PMID:26969288

  15. Cogeneration alternatives in sugar and alcohol industries. Case of study; Alternativas de cogeracao na industria sucro-alcooleira. Estudo de caso

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez Prieto, Mario Gabriel

    2003-07-01

    In the present work, a cogeneration system of sugar-alcohol cane mill is evaluated. Using the Exergetic Cost Theory, a thermo economic analysis is made for the crop corresponding to the year 2000. Previously a detailed energetic analysis was made in order to determine of the first law efficiency for steam boilers and the fuel consumption involved. The first and second law equipment's efficiencies were calculated as well as some performance criteria of the overall system. The fundamental aim of the evaluation was to obtain the cost of the principal fluxes of the system, considering a discount rate of 15 % and a capital recovery period of fifteen years for the energetic equipment in the sugar mill for the monetary cost calculations. In the analysis, was included the sugar mill juice extraction system as a control volume in order to determine the variation in the bagasse cost and its influence in the cost of other fluxes. A Thermodynamic analysis is also made, in which the increase of thermodynamic parameters is studied as a way of improving the fuel economy in Sugar Mill Factories focusing the electric energy obtained in the different alternatives. Diverse strategies are discussed, and as a result, the thermodynamic evaluations of two Proposals of Steam Cogeneration Systems are accomplished as well as the calculations of the exergetic cost. (author)

  16. Structural studies of alternative oxidase (AOX) from moniliophthora perniciosa, the causal agent of witches' broom disease in cacao: a membrane-associated protein

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, J.F.; Prado, P.F.V.; Tiezzi, H.O.; Dias, S.M.G.; Ambrosio, A.L.B. [Laboratorio Nacional de Biociencias - LNBIO, Campinas, SP (Brazil); Thomazella, D.P.T.; Teixeira, P.J.P.L.; Pereira, G.A.G. [Universidade Estadual de Campinas (UNICAMP), SP (Brazil)

    2012-07-01

    Full text: Alternative oxidase (AOX) is a protein attached to the inner mitochondrial membrane that receives electrons directly from reduced ubiquinone and catalyzes the reduction of oxygen to water. AOX is a non-proton motive terminal quinol oxidase that enables cell respiration to continue even in the presence of inhibitors targeting the complexes of the respiratory chain. This protein is present in higher plants, pathogenic fungi and some parasites. The structural characterization of AOX becomes interesting due to its potential as a fungicide target. AOX is predicted to be a monotopic interfacial membrane protein interacting with a single leaflet of the lipid bilayer, rather than transmembrane. Amino acid sequence analysis reveals the presence of two conserved glutamate-histidine motifs, identifying it as a member of the diiron carboxylate protein family. The AOX model is defined by two pairs of helices forming a four helix bundle and an additional hydrophobic connecting sequence between the two helical pairs is proposed to act as the membrane anchoring region. In this work we aim at production, purification and crystallization of the AOX protein from M. perniciosa for further structural studies of this membrane-associated protein, by X-ray protein crystallography (author)

  17. A study on synthesis of energy fuel from waste plastic and assessment of its potential as an alternative fuel for diesel engines.

    Science.gov (United States)

    Kaimal, Viswanath K; Vijayabalan, P

    2016-05-01

    The demand for plastic is ever increasing and has produced a huge amount of plastic waste. The management and disposal of plastic waste have become a major concern, especially in developing cities. The idea of waste to energy recovery is one of the promising techniques used for managing the waste plastic. This paper assesses the potential of using Waste Plastic Oil (WPO), synthesized using pyrolysis of waste plastic, as an alternative for diesel fuel. In this research work, the performance and emission characteristics of a single cylinder diesel engine fuelled with WPO and its blends with diesel are studied. In addition to neat plastic oil, three blends (PO25, PO50 and PO75) were prepared on a volumetric basis and the engine was able to run on neat plastic oil. Brake thermal efficiency of blends was lower compared to diesel, but PO25 showed similar performance to that of diesel. The emissions were reduced considerably while using blends when compared to neat plastic oil. The smoke and NOX were reduced by 22% and 17.8% respectively for PO25 than that of plastic oil.

  18. Changes among male and female visitors to practitioners of complementary and alternative medicine in a large adult Norwegian population from 1997 to 2008 (The HUNT studies

    Directory of Open Access Journals (Sweden)

    Steinsbekk Aslak

    2011-08-01

    Full Text Available Abstract Background The aim was to investigate changes in the prevalence and characteristics of male and female visitors to practitioners of complementary and alternative medicine (CAM in a large adult population from 1997 to 2008. Methods Two cross sectional adult total population health surveys from Central Norwegian (the Nord-Trøndelag Health Studies (HUNT. In 1997 42,277 and in 2008 50,713 respondents were included. Variables included demographics (age, education, working status, lifestyle (daily smoker, did hard physical activities, health status (self-rated health status, recent complaints, chronic complaints, psychiatric complaints, a range of diseases and health care use (visit general practitioner, chiropractor. A test of difference between the results of multivariable logistic regression models for each year, including all variables, was used to analyse changes from 1997 to 2008. Results In 1997 9.4% (95%CI 9.1-9.6 of the population had visited a CAM practitioner in the last 12 months and this increased to 12.6% (12.3-12.9 in 2008 (p Conclusion The increase in visits was mainly among younger people of both genders with more limited complaints. A larger proportion of the more healthy part of the population is increasing their visits to CAM practitioners.

  19. Alternatives to prison sentences: Experiences and development

    OpenAIRE

    Junger-Tas, J.

    1994-01-01

    This study presents an overview of experiences with alternative sanctions in other countries with a view to the future development of the Dutch sanctioning system. The principal objective of the study was to examine the use of alternatives to prison with respect to their effectiveness and efficiency.

  20. Alternatives to prison sentences : Experiences and development

    NARCIS (Netherlands)

    Junger-Tas, J.

    1994-01-01

    This study presents an overview of experiences with alternative sanctions in other countries with a view to the future development of the Dutch sanctioning system. The principal objective of the study was to examine the use of alternatives to prison with respect to their effectiveness and efficiency

  1. HL-LHC alternatives

    CERN Document Server

    Tomás, R; White, S

    2014-01-01

    The HL-LHC parameters assume unexplored regimes for hadron colliders in various aspects of accelerator beam dynamics and technology. This paper reviews three alternatives that could potentially improve the LHC performance: (i) the alternative filling scheme 8b+4e, (ii) the use of a 200 MHz RF system in the LHC and (iii) the use of proton cooling methods to reduce the beam emittance (at top energy and at injection). The alternatives are assessed in terms of feasibility, pros and cons, risks versus benefits and the impact on beam availability.

  2. An Alternative Method to Facilitate cDNA Cloning for Expression Studies in Mammalian Cells by Introducing Positive Blue White Selection in Vaccinia Topoisomerase I-Mediated Recombination.

    Directory of Open Access Journals (Sweden)

    Hiroshi Udo

    Full Text Available One of the most basic techniques in biomedical research is cDNA cloning for expression studies in mammalian cells. Vaccinia topoisomerase I-mediated cloning (TOPO cloning by Invitrogen allows fast and efficient recombination of PCR-amplified DNAs. Among TOPO vectors, a pcDNA3.1 directional cloning vector is particularly convenient, since it can be used for expression analysis immediately after cloning. However, I found that the cloning efficiency was reduced when RT-PCR products were used as inserts (about one-quarter. Since TOPO vectors accept any PCR products, contaminating fragments in the insert DNA create negative clones. Therefore, I designed a new mammalian expression vector enabling positive blue white selection in Vaccinia topoisomerase I-mediated cloning. The method utilized a short nontoxic LacZα peptide as a linker for GFP fusion. When cDNAs were properly inserted into the vector, minimal expression of the fusion proteins in E. coli (harboring lacZΔM15 resulted in formation of blue colonies on X-gal plates. This method improved both cloning efficiency (75% and directional cloning (99% by distinguishing some of the negative clones having non-cording sequences, since these inserts often disturbed translation of lacZα. Recombinant plasmids were directly applied to expression studies using GFP as a reporter. Utilization of the P2A peptide allowed for separate expression of GFP. In addition, the preparation of Vaccinia topoisomerase I-linked vectors was streamlined, which consisted of successive enzymatic reactions with a single precipitation step, completing in 3 hr. The arrangement of unique restriction sites enabled further modification of vector components for specific applications. This system provides an alternative method for cDNA cloning and expression in mammalian cells.

  3. Artificial nests as an alternative to studies of arboreal small mammal populations: a five-year study in the Atlantic Forest, Brazil

    Directory of Open Access Journals (Sweden)

    Diogo Loretto

    2011-06-01

    Full Text Available Despite the great diversity of Brazilian Atlantic forest small mammals, natural history of most species is unknown due to their cryptic and nocturnal habits, but also due to the inadequacy of methods to capture some species, especially those of arboreal habits. A new technique, based on the use of artificial nests (AN to record arboreal marsupials, is presented. Artificial nests were combined with traditional live traps to study the population ecology of four didelphid marsupial species. After 62 months of monitoring, 119 individuals were recorded 243 times (total success = 5.2%. Only 26 individuals (22% were recorded by both AN and live trap methods, and two of the four species were never captured by live traps, only by AN. Live traps alone would have provided biased data of the structure of small mammal assemblages, creating artificial tendencies in population dynamics of many species. Detectability estimates based on mark-recapture data could correct bias resulting from the use only live traps, but these estimates require that at least some individuals of each age class or stage are captured. Only the combination of AN and live traps can produce more accurate data on population dynamics and assemblage structure. This study demonstrates that artificial nests represent a new method that should be combined with live traps in studies of small mammal assemblages and populations.

  4. Potential of renewable and alternative energy sources

    OpenAIRE

    Konovalov, Vyacheslav Vasilievich; Pozharnitskaya, Olga Vyacheslavovna; Rostovshchikova, А.; Matveenko, Irina Alekseevna

    2015-01-01

    The article deals with application potential of clean alternative renewable energy sources. By means of system analysis the forecast for consumption of electrical energy in Tomsk Oblast as well as main energy sources of existing energy system have been studied up to 2018. Engineering potential of renewable and alternative energy sources is evaluated. Besides, ranking in the order of their efficiency descending is performed. It is concluded that Tomsk Oblast has high potential of alternative a...

  5. Alternative transportation fuels: Financing issues

    International Nuclear Information System (INIS)

    A multitude of alternative fuels could reduce air pollution and the impact of oil price shocks. Only a few of these fuels are readily available and inexpensive enough to merit serious consideration over the coming five years. In New York City, safety regulations narrow the field still further by eliminating propane. As a result, this study focuses on the three alternative fuels readily available in New York City: compressed natural gas, methanol, and electricity. Each has significant environmental benefits and each has different cost characteristics. With the Clean Air Act and the National Energy Strategy highlighting the country's need to improve urban air quality and move away from dependence on imported fuels, fleets may soon have little choice but to convert to altemative fuels. Given the potential for large infrastructure and vehicle costs, these fleets may have difficulty finding the capital to make that conversion. Ultimately, then, it will be the involvement of the private sector that will determine the success of alternative fuels. Whether it be utilities, fuel distributors or suppliers, private financing partners or others, it is critical that altemative fuels programs be structured and planned to attract their involvement. This report examines financing methods that do not involve government subsidies. It also explores financing methods that are specific to alternative fuels. Bond issues and other mechanisms that are used for conventional vehicles are not touched upon in this report. This report explores ways to spread the high cost of alternative fuels among a number of parties within the private sector. The emphasis is on structuring partnerships that suit methanol, electric, or natural gas vehicle fleets. Through these partnerships, alternative fuels may ultimately compete effectively against conventional vehicle fuels

  6. Evaluation of Expenditure Alternates

    Science.gov (United States)

    Poehlein, Gary W.; And Others

    1973-01-01

    Illustrates a system of calculating dollar expenditures over periods of time in terms of present value. The system enables planners, school boards, and administrators to compare expenditure alternatives as a decisionmaking factor. (Author)

  7. Alternatives to Nursing Homes

    Science.gov (United States)

    ... this website may not be available. Alternatives to nursing homes Before you make any decisions about long ... live and what help you may need. A nursing home may not be your only choice. Discharge ...

  8. Alternative disinfectant water treatments

    Science.gov (United States)

    Alternative disinfestant water treatments are disinfestants not as commonly used by the horticultural industry. Chlorine products that produce hypochlorous acid are the main disinfestants used for treating irrigation water. Chlorine dioxide will be the primary disinfestant discussed as an alternativ...

  9. An alternative currency

    OpenAIRE

    Frendo, Mario; Duca, Edward

    2013-01-01

    Malta- a tiny island, a minute social reality, a precursory canovaccio of European unification- has a unique asset it ought to be prouder of: culture. http://www.um.edu.mt/think/an-alternative-currency/

  10. Alternative fuel information sources

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    This short document contains a list of more than 200 US sources of information (Name, address, phone number, and sometimes contact) related to the use of alternative fuels in automobiles and trucks. Electric-powered cars are also included.

  11. Alternate strategies to obtain mass balance without the use of radiolabeled compounds: application of quantitative fluorine (19F) nuclear magnetic resonance (NMR) spectroscopy in metabolism studies.

    Science.gov (United States)

    Mutlib, Abdul; Espina, Robert; Atherton, James; Wang, Jianyao; Talaat, Rasmy; Scatina, JoAnn; Chandrasekaran, Appavu

    2012-03-19

    studies demonstrate that quantitative (19)F-NMR could be used as an alternate technique to obtain an estimate of the mass balance of fluorinated compounds, especially in early drug development where attrition of the compounds is high, and cost savings could be realized through the use of such a technique rather than employing radioactive compounds. The potential application of qNMR in conducting early human ADME studies with fluorinated compounds is also discussed. PMID:22292524

  12. Finding alternatives to swidden agriculture

    DEFF Research Database (Denmark)

    Rahman, Syed Ajijur; Jacobsen, Jette Bredahl; Healey, John Robert;

    2016-01-01

    alternative to swidden cultivation, which may potentially help protect local forest. The Gunung Salak valley in West Java, Indonesia is presented as a case study. Based on farmers’ and experts’ assessment, costs and benefits have been estimated, which show that the two investigated agroforestry systems have...... positively to conservation of local forests. Increasing the adoption of agroforestry farming in the study area will require support to overcome capacity constraints....

  13. Hospital diversification: evaluating alternatives.

    Science.gov (United States)

    Hammer, L

    1987-05-01

    The appropriateness of diversification as a growth strategy for hospitals is discussed, and planning for diversification is described. Because new forms of health-care delivery are now in direct competition with hospitals, many hospitals are confronting environmental pressures and preparing for future survival through diversification. To explore the potential risks and benefits of diversification, the hospital must identify opportunities for new business ventures. Diversification can be "related," through an expansion of the primary product line (health care), or "unrelated," into areas not directly associated with health care. The hospital must establish specific criteria for evaluating each diversification alternative, and the two or three most attractive options should be analyzed further through a financial feasibility study. The hospital should also seek legal advice to determine the implications of diversification for maintenance of tax status, antitrust limitations, and applicability of certificate of need. Although diversification may not be appropriate for every institution, hospitals should consider it as a strategy for increasing their revenue base, confronting environmental pressures, and securing future survival. PMID:3300300

  14. Hospital diversification: evaluating alternatives.

    Science.gov (United States)

    Hammer, L

    1987-05-01

    The appropriateness of diversification as a growth strategy for hospitals is discussed, and planning for diversification is described. Because new forms of health-care delivery are now in direct competition with hospitals, many hospitals are confronting environmental pressures and preparing for future survival through diversification. To explore the potential risks and benefits of diversification, the hospital must identify opportunities for new business ventures. Diversification can be "related," through an expansion of the primary product line (health care), or "unrelated," into areas not directly associated with health care. The hospital must establish specific criteria for evaluating each diversification alternative, and the two or three most attractive options should be analyzed further through a financial feasibility study. The hospital should also seek legal advice to determine the implications of diversification for maintenance of tax status, antitrust limitations, and applicability of certificate of need. Although diversification may not be appropriate for every institution, hospitals should consider it as a strategy for increasing their revenue base, confronting environmental pressures, and securing future survival.

  15. A more robust predictor of ideomotor dyspraxia: study on an alternative scoring method of the Bergès-Lézine's Imitation of Gestures test.

    Science.gov (United States)

    Vaivre-Douret, L

    2002-01-01

    Use of the traditional Bergès-Lézine standardization [Test d'imitation de gestes (1963).] allowed us to confirm praxic disorders in children who are encountering obvious motor difficulties. However, in comparison to other neuropsychological assessments carried out on these children, it does not enable us to precociously pinpoint disorders in praxic organization. By means of a newly evaluated method (1997) developed on the basis of the Bergès-Lézine Imitation of Gestures test (1963), we retroactively assessed a group of children (N=10) who had been observed in a longitudinal study at the age of 3-5 years and at 7-8 years and assessed with the Bergès-Lézine version (1963) of the Imitation of Gestures test. Our revised test (1997) takes into account the quantitative factor of success, as well as the qualitative factor of movement planning. It facilitates the early detection of motor organization disorders, in correlation with other neuropsychological assessments carried out on these children. Comparative clinical findings with the same group of children tested using the Bergès-Lézine version and ours indicate that our version detects, more robustly, children encountering difficulties resulting from ideomotor dyspraxia, not identified by the Bergès-Lézine test (1963). Our alternative scoring method of Bergès-Lézine's test contributes largely to early detection of instrumental difficulties in children. Additionally, its predictive capacity makes it possible to apprehend disorders in distal and digital neuromotor functions. PMID:14589751

  16. SU-E-J-271: A Feasibility Study to Utilize XR-QA2 Radiochromic Films as An Alternative Tool for Measuring Beam Parameters of Kilovoltage CBCT Systems

    Energy Technology Data Exchange (ETDEWEB)

    Morales-Paliza, M; Ding, G [Vanderbilt University, Nashville, TN (United States)

    2014-06-01

    Purpose: The beam parameters of the x-ray beams used in image guidance are difficult to measure in water due to the low exposure. This study is to investigate if XR-QA2 radiochromic films can be used in obtaining beam parameters, such as beam profiles and outputs for kV-CBCT systems. Methods: The kV-CBCT beams were from a Varian OBI system. The films used were XR-QA2-GAFCHROMICTM films placed in the middle of two Plastic -Water slab phantoms at isocenter. The scanner used to analyze the films was an Epson Expression 1680 flat-bed scanner. Pre and 24 h-post-irradiated scans of films were obtained by using the reflective mode. The corresponding pixel-by-pixel dose in the films was obtained using a dose calibration equation as a function of net reflectance from the literature. Beam profiles of different scan protocols with and without bow-tie filters were measured. Monte Carlo simulations were used to compare the accuracy of the measured dose profiles. Results: The beam profiles measured from XR-QA2 films for different clinical default kV-CBCT scan protocols were benchmarked against Monte Carlo simulated profiles which have been validated by measurements performed in water phantom. We confirmed that a minimum post-irradiated time of 24 hours is necessary to pass to scan the films to account for light scatter stability. We found that the uncertainties of the results depend on the scan orientation of the film when analyzed in different directions. Conclusion: The XR-QA2 radiochromic films are sensitive to measure the x-ray beam profiles with irradiated dose ranging 1–5 cGy. The film measurements can be performed with an easy setup compared to ion chamber measurements in a water phantom. These films provide an alternative method to obtain the beam profiles for kV-CBCT beams.

  17. Wood ash amendment to biogas reactors as an alternative to landfilling? A preliminary study on changes in process chemistry and biology.

    Science.gov (United States)

    Podmirseg, Sabine M; Seewald, Martin S A; Knapp, Brigitte A; Bouzid, Ourdia; Biderre-Petit, Corinne; Peyret, Pierre; Insam, Heribert

    2013-08-01

    Wood ash addition to biogas plants represents an alternative to commonly used landfilling by improving the reactor performance, raising the pH and alleviating potential limits of trace elements. This study is the first on the effects of wood ash on reactor conditions and microbial communities in cattle slurry-based biogas reactors. General process parameters [temperature, pH, electrical conductivity, ammonia, volatile fatty acids, carbon/nitrogen (C/N), total solids (TS), volatile solids, and gas quantity and quality] were monitored along with molecular analyses of methanogens by polymerase chain reaction- denaturing gradient gel electrophoresis and modern microarrays (archaea and bacteria). A prompt pH rise was observed, as was an increase in C/N ratio and volatile fatty acids. Biogas production was inhibited, but recovered to even higher production rates and methane concentration after single amendment. High sulphur levels in the wood ash generated hydrogen sulphide and potentially hampered methanogenesis. Methanosarcina was the most dominant methanogen in all reactors; however, diversity was higher in ash-amended reactors. Bacterial groups like Firmicutes, Proteobacteria and Acidobacteria were favoured, which could improve the hydrolytic efficiency of the reactors. We recommend constant monitoring of the chemical composition of the used wood ash and suggest that ash amendment is adequate if added to the substrate at a rate low enough to allow adaptation of the microbiota (e.g. 0.25 g g(-1) TS). It could further help to enrich digestate with important nutrients, for example phosphorus, calcium and magnesium, but further experiments are required for the evaluation of wood ash concentrations that are tolerable for anaerobic digestion.

  18. The potential of complementary and alternative medicine in promoting well-being and critical health literacy: a prospective, observational study of shiatsu

    Directory of Open Access Journals (Sweden)

    Long Andrew F

    2009-06-01

    Full Text Available Abstract Background The potential contribution of complementary and alternative medicine (CAM modalities to promote and support critical health literacy has not received substantial attention within either the health promotion or the CAM literature. This paper explores the potential of one CAM modality, shiatsu, in promoting well-being and critical health literacy. Methods Data are drawn from a longitudinal, 6 months observational, pragmatic study of the effects and experience of shiatsu within three European countries (Austria, Spain and the UK. Client postal questionnaires included: advice received, changes made 6 months later, clients 'hopes' from having shiatsu and features of the client-practitioner relationship. Result At baseline, three-quarters of clients (n = 633 received advice, on exercise, diet, posture, points to work on at home or other ways of self-care. At 6 months follow-up, about four-fifths reported making changes to their lifestyle 'as a result of having shiatsu treatment', including taking more rest and relaxation or exercise, changing their diet, reducing time at work and other changes such as increased body/mind awareness and levels of confidence and resolve. Building on the findings, an explanatory model of possible ways that a CAM therapy could contribute to health promotion is presented to guide future research, both within and beyond CAM. Conclusion Supporting individuals to take control of their self-care requires advice-giving within a supportive treatment context and practitioner relationship, with clients who are open to change and committed to maintaining their health. CAM modalities may have an important role to play in this endeavour.

  19. Wood ash amendment to biogas reactors as an alternative to landfilling? A preliminary study on changes in process chemistry and biology.

    Science.gov (United States)

    Podmirseg, Sabine M; Seewald, Martin S A; Knapp, Brigitte A; Bouzid, Ourdia; Biderre-Petit, Corinne; Peyret, Pierre; Insam, Heribert

    2013-08-01

    Wood ash addition to biogas plants represents an alternative to commonly used landfilling by improving the reactor performance, raising the pH and alleviating potential limits of trace elements. This study is the first on the effects of wood ash on reactor conditions and microbial communities in cattle slurry-based biogas reactors. General process parameters [temperature, pH, electrical conductivity, ammonia, volatile fatty acids, carbon/nitrogen (C/N), total solids (TS), volatile solids, and gas quantity and quality] were monitored along with molecular analyses of methanogens by polymerase chain reaction- denaturing gradient gel electrophoresis and modern microarrays (archaea and bacteria). A prompt pH rise was observed, as was an increase in C/N ratio and volatile fatty acids. Biogas production was inhibited, but recovered to even higher production rates and methane concentration after single amendment. High sulphur levels in the wood ash generated hydrogen sulphide and potentially hampered methanogenesis. Methanosarcina was the most dominant methanogen in all reactors; however, diversity was higher in ash-amended reactors. Bacterial groups like Firmicutes, Proteobacteria and Acidobacteria were favoured, which could improve the hydrolytic efficiency of the reactors. We recommend constant monitoring of the chemical composition of the used wood ash and suggest that ash amendment is adequate if added to the substrate at a rate low enough to allow adaptation of the microbiota (e.g. 0.25 g g(-1) TS). It could further help to enrich digestate with important nutrients, for example phosphorus, calcium and magnesium, but further experiments are required for the evaluation of wood ash concentrations that are tolerable for anaerobic digestion. PMID:23831776

  20. Mixed oxide conversion facility alternative conceptual designs

    International Nuclear Information System (INIS)

    Allied-General Nuclear Services recently performed studies to evaluate alternative proliferation-resistant flowsheets of the uranium-based LWR fuel cycle. The alternatives evaluated consist of coprocessing schemes with either a gamma or a heat spike added. A literature search and evaluation were performed to select a process technology for mixed oxide coconversion. The COPRECAL process was chosen as the most suitable conversion process technology. Three alternative mixed oxide conversion facility design concepts were prepared based on the COPRECAL technology. These alternative concepts are compared to a pure plutonium conversion facility. Facility designs, relative proliferation resistance, and cost estimates are discussed

  1. Characteristics of users and implications for the use of complementary and alternative medicine in Ghanaian cancer patients undergoing radiotherapy and chemotherapy: a cross- sectional study

    Directory of Open Access Journals (Sweden)

    Yarney Joel

    2013-01-01

    Full Text Available Abstract Background There is widespread use of Complementary and Alternative Medicine (CAM in Ghana, driven by cultural consideration and paradigm to disease causation. Whether there is concurrent use of conventional medicine and CAM in cancer patients is unknown. This study investigates the prevalence, pattern and predictors of CAM use in cancer patients. Overlapping toxicity, sources of information, and whether users inform their doctor about CAM use is examined. Method Cross-sectional study using a questionnaire administered to cancer patients, who were receiving radiotherapy and or chemotherapy or had recently completed treatment at a single institution was used. Results Ninety eight patients participated in the study with a mean age of 55.5 (18–89, made up of 51% females. Married individuals formed 56% of the respondents, whilst 49% had either secondary or tertiary education. Head and neck cancer patients were 15.3%, breast (21.4%, abdomen/pelvic cancers constituted (52%.Seventy seven (78.6% patients received radiotherapy only, 16.3% received radiation and chemotherapy and 5.3% had chemotherapy only. Ninety five patients were diagnosed of cancer within the past 24 months,73.5% were CAM users as follows; massage(66.3%, herbal(59.2%, mega vitamins(55.1%, Chinese medicine(53.1%,and prayer(42.9%. Sixty eight percent were treated with curative intent. Overlapping toxicity was reported. Majority (83.3% of users had not informed their doctor about CAM use. On univariate analysis, female (p=0.004 and palliative patients, p=0.032 were more likely to be CAM users. Multivariate analysis identified female (p Friends and Media are the main sources of information on CAM. There was increase in CAM use after the diagnosis of cancer mainly for Chinese Medicine and vitamins. Conclusion There is high CAM usage among Cancer patients, comparable to use in the general population, there is concurrent use of CAM and conventional medicine with reported

  2. Diverse alternative back-splicing and alternative splicing landscape of circular RNAs

    Science.gov (United States)

    Zhang, Xiao-Ou; Dong, Rui; Zhang, Yang; Zhang, Jia-Lin; Luo, Zheng; Zhang, Jun; Chen, Ling-Ling; Yang, Li

    2016-01-01

    Circular RNAs (circRNAs) derived from back-spliced exons have been widely identified as being co-expressed with their linear counterparts. A single gene locus can produce multiple circRNAs through alternative back-splice site selection and/or alternative splice site selection; however, a detailed map of alternative back-splicing/splicing in circRNAs is lacking. Here, with the upgraded CIRCexplorer2 pipeline, we systematically annotated different types of alternative back-splicing and alternative splicing events in circRNAs from various cell lines. Compared with their linear cognate RNAs, circRNAs exhibited distinct patterns of alternative back-splicing and alternative splicing. Alternative back-splice site selection was correlated with the competition of putative RNA pairs across introns that bracket alternative back-splice sites. In addition, all four basic types of alternative splicing that have been identified in the (linear) mRNA process were found within circRNAs, and many exons were predominantly spliced in circRNAs. Unexpectedly, thousands of previously unannotated exons were detected in circRNAs from the examined cell lines. Although these novel exons had similar splice site strength, they were much less conserved than known exons in sequences. Finally, both alternative back-splicing and circRNA-predominant alternative splicing were highly diverse among the examined cell lines. All of the identified alternative back-splicing and alternative splicing in circRNAs are available in the CIRCpedia database (http://www.picb.ac.cn/rnomics/circpedia). Collectively, the annotation of alternative back-splicing and alternative splicing in circRNAs provides a valuable resource for depicting the complexity of circRNA biogenesis and for studying the potential functions of circRNAs in different cells. PMID:27365365

  3. Alternatives of menopausal hormone therapy

    Directory of Open Access Journals (Sweden)

    Kutlešić Ranko M.

    2016-01-01

    Full Text Available Introduction. It has been generally accepted that the benefits of menopausal hormone therapy outweigh the risks, but there are still some concerns about the administration of menopausal hormone therapy, which has introduced alternative treatments. Pharmacological Alternatives. Central alpha-2 agonist clonidine is only marginally more effective than placebo, and significantly less effective than estrogen. Antiepileptic drug gabapentin reduces hot flashes; however, it is less effective than estrogen. Selective serotonin reuptake inhibitors (paroxetine and fluoxetine and selective noradrenaline reuptake inhibitors (venlafaxine reduce vasomotor symptoms and improve depression, anxiety and sleep. Results of studies about dehydroepiandrosterone effects on menopausal symptoms are inconsistent and additional investigations are needed. Non-Pharmacological Alternatives. Stellatum ganglion blockade is a successful treatment for reducing vasomotor symptoms in patients with contraindications for menopausal hormone therapy. Efficacy of acupuncture, homeopathy and reflexology should be proved by adequate studies. Phytoestrogens could reduce vasomotor symptoms but to a lesser extent than conventional menopausal hormone therapy. However, they have not been proved yet to provide cardiovascular protection and prevention of osteoporosis, nor they could be recommended instead of traditional menopausal hormone therapy. There is a concern about their undesirable effects. Adequate diet, unchanging body weight within ideal values and adequate physical activities have beneficial long-term effects, first of all on preservation of bone density. Alternatives for Atrophic Changes of Vaginal Epithelium. Menopausal symptoms resulting from vaginal atrophy could be resolved by use of hydrophilic preparations, lubricants and topical lidocaine cream or 4% lidocaine water solution for dyspareunia. Conclusion. If there are contrain­dications to menopausal hormone therapy or

  4. Design and Analysis of Salmonid Tagging Studies in the Columbia Basin, Volume XVI; Alternative Designs for Future Adult PIT-Tag Detection Studies, 2000 Technical Report.

    Energy Technology Data Exchange (ETDEWEB)

    Perez-Comas, Jose A.; Skalski, John R. (University of Washington, School of Fisheries, Seattle, WA)

    2000-09-25

    In the advent of the installation of a PIT-tag interrogation system in the Cascades Island fish ladder at Bonneville Dam (BON), and other CRB dams, this overview describes in general terms what can and cannot be estimated under seven different scenarios of adult PIT-tag detection capabilities in the CRB. Moreover, this overview attempted to identify minimal adult PIT-tag detection configurations required by the ten threatened Columbia River Basin (CRB) chinook and steelhead ESUs. A minimal adult PIT-tag detection configuration will require the installation of adult PIT-tag detection facilities at Bonneville Dam and another dam above BON. Thus, the Snake River spring/summer and fall chinook salmon, and the Snake River steelhead will require a minimum of three dams with adult PIT-tag detection capabilities to guarantee estimates of ''ocean survival'' and at least of one independent, in-river returning adult survival (e.g., adult PIT-tag detection facilities at BON and LGR dams and at any other intermediary dam such as IHR). The Upper Columbia River spring chinook salmon and steelhead will also require a minimum of three dams with adult PIT-tag detection capabilities: BON and two other dams on the BON-WEL reach. The current CRB dam system configuration and BPA's and COE's commitment to install adult PIT-tag detectors only in major CRB projects will not allow the estimation of an ''ocean survival'' and of any in-river adult survival for the Lower Columbia River chinook salmon and steelhead. The Middle Columbia River steelhead ESU will require a minimum of two dams with adult PIT-tag detection capabilities: BON and another upstream dam on the BON-McN reach. Finally, in spite of their importance in terms of releases, PIT-tag survival studies for the Upper Willamette chinook and Upper Willamette steelhead ESUs cannot be perform with the current CRB dam system configuration and PIT-tag detection capabilities.

  5. Alternative fuels for vehicles; Alternative drivmidler

    Energy Technology Data Exchange (ETDEWEB)

    2012-02-15

    Up until 2020 and onwards the analysis indicates that especially electricity, biogas and natural gas as propellants is economically attractive compared to conventional gasoline and diesel while other fuels have the same or higher costs for petrol and diesel. Especially biogas and electricity will also offer significant reductions in CO{sub 2} emissions, but also hydrogen, methanol, DME and to a lesser extent the second generation bioethanol and most of the other alternative fuels reduce CO{sub 2} emissions. Use of the traditional food-based first generation biofuels involves, at best, only modest climate benefits if land use changes are counted, and at worst, significant negative climate effects. Natural gas as a propellant involves a moderate climate gain, but may play a role for building infrastructure and market for gaseous fuels in large fleets, thereby contributing to the phasing in of biogas for transport. The electric-based automotive fuels are the most effective due to a high efficiency of the engine and an increasing proportion of wind energy in the electricity supply. The methanol track also has a relatively high efficiency. Among the others, the track based on diesel engines (biodiesel) is more effective than the track based on gasoline/Otto engines (gas and ethanol) as a result of the diesel engine's better efficiency. For the heavy vehicles all the selected alternative fuels to varying degrees reduce emissions of CO{sub 2}, particularly DME based on wood. The only exception to this is - as for passenger cars - the propellant synthetic diesel based on coal. (LN).

  6. Study on American Alternative CTE of Teachers’ Induction Training Program%美国CTE选择性证书教师入职培训研究

    Institute of Scientific and Technical Information of China (English)

    马妍

    2013-01-01

    美国生涯与技术教育的教师一直匮乏,备选证书(alternative certificate)的制定为教师队伍的壮大贡献了力量,但是备选教师(alternative teacher)在初次教学时遇到了很多阻碍,因此,美国南区教育委员会实施了美国 CTE 选择性证书教师入职培训。针对此项入职培训介绍其背景、培训概况以及培训的效果。%There has been a shortage in the number of career and technical education teachers in American. Alternative certificate has contributed to the growth of the teachers. But alternative teachers, when teaching for the first time, might meet with many obstacles. Therefore, the United States for the southern district education commission adopted the teacher induction model of CTE selective certificate. This paper has introduced its background, training, induction and training result.

  7. Alternating treatment with didanosine and zidovudine versus either drug alone for the treatment of advanced HIV infection. The Alter Study. Nordic HIV Therapy Group

    DEFF Research Database (Denmark)

    Gerstoft, J; Melander, H; Bruun, J N;

    1997-01-01

    The efficacy and safety of an alternating regime with zidovudine and didanosine versus treatment with either drug alone were investigated in a randomized, open, controlled trial, 552 patients with advanced HIV infection, 47% of whom had received prior treatment with zidovudine, were enrolled...

  8. Catalysis for alternative energy generation

    CERN Document Server

    2012-01-01

    Summarizes recent problems in using catalysts in alternative energy generation and proposes novel solutions  Reconsiders the role of catalysis in alternative energy generation  Contributors include catalysis and alternative energy experts from across the globe

  9. Alternative Structures and Bihamiltonian Systems

    CERN Document Server

    Marmo, G; Simoni, A; Ventriglia, F

    2002-01-01

    In the study of bi-Hamiltonian systems (both classical and quantum) one starts with a given dynamics and looks for all alternative Hamiltonian descriptions it admits.In this paper we start with two compatible Hermitian structures (the quantum analog of two compatible classical Poisson brackets) and look for all the dynamical systems which turn out to be bi-Hamiltonian with respect to them.

  10. Domestic energy alternatives

    International Nuclear Information System (INIS)

    These alternatives include biomass, clean coal, geothermal, hydropower, natural gas, nuclear, solar and photovoltaic, and wind. With the current, volatile situation in the Middle East, this nation's political leaders appear to be left scratching their heads in their attempts to come up with new, sound, energy policies to reduce our dependence on foreign oil. Therefore, the FORTNIGHTLY's editorial staff thought that this might be an opportune time to briefly examine some home-grown and environmentally responsible fuel alternatives to black gold. While some of these electricity-producing technologies are still on the horizon, others are available now

  11. Spectroscopic studies of the binding of Cu(II) complexes of oxicam NSAIDs to alternating G-C and homopolymeric G-C sequences

    Science.gov (United States)

    Chakraborty, Sreeja; Bose, Madhuparna; Sarkar, Munna

    2014-03-01

    Drugs belonging to the Non-steroidal anti-inflammatory (NSAID) group are not only used as anti-inflammatory, analgesic and anti-pyretic agents, but also show anti-cancer effects. Complexing them with a bioactive metal like copper, show an enhancement in their anti-cancer effects compared to the bare drugs, whose exact mechanism of action is not yet fully understood. For the first time, it was shown by our group that Cu(II)-NSAIDs can directly bind to the DNA backbone. The ability of the copper complexes of NSAIDs namely meloxicam and piroxicam to bind to the DNA backbone could be a possible molecular mechanism behind their enhanced anticancer effects. Elucidating base sequence specific interaction of Cu(II)-NSAIDs to the DNA will provide information on their possible binding sites in the genome sequence. In this work, we present how these complexes respond to differences in structure and hydration pattern of GC rich sequences. For this, binding studies of Cu(II) complexes of piroxicam [Cu(II)-(Px)2 (L)2] and meloxicam [Cu(II)-(Mx)2 (L)] with alternating GC (polydG-dC) and homopolymeric GC (polydG-polydC) sequences were carried out using a combination of spectroscopic techniques that include UV-Vis absorption, fluorescence and circular dichroism (CD) spectroscopy. The Cu(II)-NSAIDs show strong binding affinity to both polydG-dC and polydG-polydC. The role reversal of Cu(II)-meloxicam from a strong binder of polydG-dC (Kb = 11.5 × 103 M-1) to a weak binder of polydG-polydC (Kb = 5.02 × 103 M-1), while Cu(II)-piroxicam changes from a strong binder of polydG-polydC (Kb = 8.18 × 103 M-1) to a weak one of polydG-dC (Kb = 2.18 × 103 M-1), point to the sensitivity of these complexes to changes in the backbone structures/hydration. Changes in the profiles of UV absorption band and CD difference spectra, upon complex binding to polynucleotides and the results of competitive binding assay using ethidium bromide (EtBr) fluorescence indicate different binding modes in each

  12. Alternative and Integrative Medicine

    Science.gov (United States)

    ... are the healthcare rituals practiced by a given culture (eg, Asian, Indian, African). Homeopathic Medicine: This alternative medicine system is based on the principle that “like cures like.” In other words, the same substance ... American Brain Tumor Association 8550 W. Bryn Mawr Ave. ...

  13. Alternative Energy Busing

    Science.gov (United States)

    LaFee, Scott

    2012-01-01

    In recent years, school districts have converted portions of their bus fleets to cleaner-burning, sometimes cheaper, alternative fossil fuels, such as compressed natural gas or propane. Others have adopted biodiesel, which combines regular diesel with fuel derived from organic sources, usually vegetable oils or animal fats. The number of biodiesel…

  14. Compensated pulsed alternator

    International Nuclear Information System (INIS)

    This invention relates to an electromechanical energy converter with inertial energy storage. The device, a single phase, two or multi-pole alternator with stationary field coils, and a rotating armature is provided. The rotor itself may be of laminated steel for slower pulses or for faster pulses should be nonmagnetic and electrically nonconductive in order to allow rapid penetration of the field as the armature coil rotates. The armature coil comprises a plurality of power generating conductors mounted on the rotor. The alternator may also include a stationary or counterrotating compensating coil to increase the output voltage thereof and to reduce the internal impedance of the alternator at the moment of peak output. As the machine voltage rises sinusoidally, an external trigger switch is adapted to be closed at the appropriate time to create the desired output current from said alternator to an external load circuit, and as the output current passes through zero a self-commutating effect is provided to allow the switch to disconnect the generator from the external circuit

  15. Alternatives to Violence.

    Science.gov (United States)

    Children Today, 1994

    1994-01-01

    Notes that our capacity to diffuse conflict rests in our ability to recognize and verbalize feelings, develop empathy, and think of alternatives to violence. Explores the influence of role models and culture on violence and how the media can use violent images effectively in helping us confront a culture of violence. (HTH)

  16. Alternatives to Traditional Notation.

    Science.gov (United States)

    Gaare, Mark

    1997-01-01

    Provides a introduction and overview to alternative music notation systems. Describes guitar tablature, accordion tablature, klavarskribo (a keyboard notational system developed by Cornelius Pot, a Dutch engineer), and the digital piano roll. Briefly discusses the history of notation reform and current efforts. Includes examples from scores. (MJP)

  17. Alternatives in solar energy

    Science.gov (United States)

    Schueler, D. G.

    1978-01-01

    Although solar energy has the potential of providing a significant source of clean and renewable energy for a variety of applications, it is expected to penetrate the nation's energy economy very slowly. The alternative solar energy technologies which employ direct collection and conversion of solar radiation as briefly described.

  18. Quantitative Study of Elasticity of Rabbit VX2 Liver Tumor with Alternated Cooling and Heating Treatment based on ARFI Ultrasound Imaging Technique

    OpenAIRE

    Di Sun; Cong Wei; E. Shen; Tao Ying; Bing Hu

    2016-01-01

    Acoustic radiation force impulse (ARFI) ultrasound imaging technique is used to quantitatively evaluate the elasticity of rabbit VX2 liver tumor with alternated cooling and heating treatment (ACHT). ACHT was performed on fifteen VX2 liver tumor models established in fifteen male New Zealand white rabbits with open tumor plant. ARFI was performed on day 0, 1, 7 and 14 after ACHT and shear wave velocity (SWV) in ARFI was recorded to evaluate the elasticity of the treated area. The SWV value of ...

  19. Break the Green Belt? The differences between green belt and its alternative green wedge : A comparative study of London and Stockholm

    OpenAIRE

    Kong, Luyao

    2012-01-01

    The paper sets out to compare two widely applied planning strategies--- green belt and green wedge--- to understand if as an alternative, the green wedge has more strengths than green belt. Green belt has long been the planning policy with a steady position in UK, and also accepted by other countries, Australia, Japan, Korea for example. But during recent years, this policy has been under accusation for fostering un-sustainability, housing shortage and value degradation of the green space. A ...

  20. Overcoming Barriers to Scaling Up Sustainable Alternative Food Systems: A Comparative Case Study of Two Ontario-Based Wholesale Produce Auctions

    Directory of Open Access Journals (Sweden)

    Rylea Johnson

    2016-04-01

    Full Text Available Conventional food systems are viewed by the literature as unsustainable in that they provide consumers with convenience while disconnecting them from producers thus leading to environmental and social problems. By contrast, sustainable or “alternative” food systems are viewed as correcting such problems. Wholesale produce auctions, which are well established in the Old Order Mennonite community, are physical sites where large quantities of produce are sold through a competitive bidding process to local buyers. These are seen as a way of better connecting producers and consumers and thus realizing a more sustainable food system. However, this potential has not been tested. Therefore, this paper explores two produce auctions in southwestern Ontario, Canada, using an interview based methodology (N = 48 and demonstrates that despite wholesale produce auctions offering many opportunities to promote the benefits of alternative food systems, produce auctions are limited in that they fail to provide a practical and functional way of distributing food to individual consumers. Overall, this research highlights what appears to be a tension in the alternative food systems literature: producers and consumers may be simultaneously looking for the sustainability benefits associated with “alternative food systems” without wanting to sacrifice any of the convenience found in conventional food systems.

  1. Titanium alloys as alternative material for the supercontainer shell in the KBS-3H concept. A preliminary Ti-clay interaction study

    International Nuclear Information System (INIS)

    Ti alloys have been proposed as alternative materials to steel for the supercontainer shell surrounding the bentonite buffer in the KBS-3H disposal concept. Ti-based materials display high strength and are known to behave chemically inert under a variety of conditions. This preliminary study addresses the suitability of titanium as supercontainer material with regard to the performance of the clay buffer. Thus, possible titanium-bentonite interactions which may adversely affect the buffer's safety functions are evaluated by means of a literature and a preliminary experimental assessment. Titanium metals display very low corrosion rates (2 which forms a passive surface corrosion layer under both oxic and reducing conditions. The interactions between titanium and clay have been barely studied so far. Preliminary long-term data obtained by Prof. Olefjord and co-workers from Chalmers (S) in the 1980s (as part of SKB's canister program) suggests similar corrosion rates in compacted bentonite compared to those measured in water, i.e. 2 or mixed (Fe, Ti) oxide, (iv) Ti precipitated as separate silicate phase and (v) polymerized as cross-linked TiO2 units in the interlayer (Ti pillared clay). The latter two transformation products would have the strongest impact on the buffer, but are improbable on the basis of current knowledge. A preliminary batch-type investigation has been carried out to shed more light on Ti-clay interaction processes and on the Ti species resulting from these interactions. Purified MX-80 bentonite was mixed with metallic Ti nano powder and foil at different pH and temperature conditions. After several months, solid and solute samples from the first set of tests were analyzed by wet chemistry and quantitative X-ray fluorescence analysis. The chemical speciation of Ti was analyzed with XAS. In addition to reacted samples, a number of reference and starting materials (e.g. MX-80, Rokle bentonite, Opalinus Clay, Illite du Puy) were characterized by XRF

  2. Implementation barriers of alternative transport fuels

    Energy Technology Data Exchange (ETDEWEB)

    Troelstra, W.P. [Innas, Breda (Netherlands); Smith, A. [AEA Technology, London (United Kingdom); Bol, M. [Sypher Mueller International, Morristown, New Jersey (United Kingdom)

    1999-02-01

    The study on the title subject aims to present an overview of the practical barriers associated with the introduction of alternative fuels for transport applications in IEA countries. The aim is to provide an information source to which potential users can refer when deciding whether to introduce an alternative fuel. The report will highlight potential problems so that users can either select the alternative fuel best suited to their needs, or implement possible solutions to the problems. The study covers natural gas (both compressed (CNG) and liquefied (LNG)), LPG (liquefied petroleum gas), ethanol (mainly bio-ethanol), methanol, bio-diesel, hydrogen, DME(dimethyl ether), and electricity. 48 refs.

  3. Context-driven expectations about focus alternatives.

    Science.gov (United States)

    Kim, Christina S; Gunlogson, Christine; Tanenhaus, Michael K; Runner, Jeffrey T

    2015-06-01

    What is conveyed by a sentence frequently depends not only on the descriptive content carried by its words, but also on implicit alternatives determined by the context of use. Four visual world eye-tracking experiments examined how alternatives are generated based on aspects of the discourse context and used in interpreting sentences containing the focus operators only and also. Experiment 1 builds on previous reading time studies showing that the interpretations of only sentences are constrained by alternatives explicitly mentioned in the preceding discourse, providing fine-grained time course information about the expectations triggered by only. Experiments 2 and 3 show that, in the absence of explicitly mentioned alternatives, lexical and situation-based categories evoked by the context are possible sources of alternatives. While Experiments 1-3 all demonstrate the discourse dependence of alternatives, only explicit mention triggered expectations about alternatives that were specific to sentences with only. By comparing only with also, Experiment 4 begins to disentangle expectations linked to the meanings of specific operators from those generalizable to the class of focus-sensitive operators. Together, these findings show that the interpretation of sentences with focus operators draws on both dedicated mechanisms for introducing alternatives into the discourse context and general mechanisms associated with discourse processing. PMID:25797456

  4. Alternatives to Higgs scalars

    International Nuclear Information System (INIS)

    We discuss alternatives to the Higgs Scalar doublet Φ of the minimal standard model. In particular we review technicolor (TC) and extended technicolor (ETC), and show that the threat of flavour changing neutral currents (FCNC's) is avoided by walking TC and/or strongly coupled ETC. The phenomenology of minimal TC and the techni-family is discussed. Finally we consider the possibility that the Higgs doublet Φ is a composite bound state of quarks from the third (or fourth) family

  5. Alternatives to ECMO.

    OpenAIRE

    Donn, S M

    1994-01-01

    The past decade has witnessed technological advancements which are unparalleled in neonatology. ECMO has been demonstrated to be a powerful rescue treatment, but has perhaps been overutilised and is not universally available. Alternative treatments have been shown to be both safe and efficacious in the management of infants with respiratory failure. Direct head to head clinical trials will probably be necessary to establish appropriate criteria and indications for use, given the wide diversit...

  6. Alternative approaches in IVF

    OpenAIRE

    Fauser, Bart; Bouchard, P.; Coelingh Bennink, H.J.; Collins, John; Devroey, P.; Evers, Johannes; Van Steirteghem, A

    2002-01-01

    textabstractVarious new developments in clinical and basic science which may impact on IVF in the near or distant future will be discussed in this review. These key areas include the regulation of early follicle development and the extended in-vitro culture of oocytes and embryos. Moreover, alternative compounds and ovarian stimulation protocols will be discussed, along with highlights in the development of the cryopreservation of excess oocytes or embryos. Finally, the health economics of IV...

  7. Metamaterials critique and alternatives

    CERN Document Server

    Munk, Ben A

    2009-01-01

    A Convincing and Controversial Alternative Explanation of Metamaterials with a Negative Index of Refraction In a book that will generate both support and controversy, one of the world's foremost authorities on periodic structures addresses several of the current fashions in antenna design-most specifically, the popular subject of double negative metamaterials. Professor Munk provides a comprehensive theoretical electromagnetic investigation of the issues and concludes that many of the phenomena claimed by researchers may be impossible. While denying the existence of negative refractio

  8. Alternative Energy Sources

    CERN Document Server

    Michaelides, Efstathios E (Stathis)

    2012-01-01

    Alternative Energy Sources is designed to give the reader, a clear view of the role each form of alternative energy may play in supplying the energy needs of the human society in the near and intermediate future (20-50 years).   The two first chapters on energy demand and supply and environmental effects, set the tone as to why the widespread use of alternative energy is essential for the future of human society. The third chapter exposes the reader to the laws of energy conversion processes, as well as the limitations of converting one energy form to another. The sections on exergy give a succinct, quantitative background on the capability/potential of each energy source to produce power on a global scale. The fourth, fifth and sixth chapters are expositions of fission and fusion nuclear energy. The following five chapters (seventh to eleventh) include detailed descriptions of the most common renewable energy sources – wind, solar, geothermal, biomass, hydroelectric – and some of the less common sources...

  9. State alternative route designations

    Energy Technology Data Exchange (ETDEWEB)

    1989-07-01

    Pursuant to the Hazardous Materials Transportation Act (HMTA), the Department of Transportation (DOT) has promulgated a comprehensive set of regulations regarding the highway transportation of high-level radioactive materials. These regulations, under HM-164 and HM-164A, establish interstate highways as the preferred routes for the transportation of radioactive materials within and through the states. The regulations also provide a methodology by which a state may select alternative routes. First,the state must establish a ``state routing agency,`` defined as an entity authorized to use the state legal process to impose routing requirements on carriers of radioactive material (49 CFR 171.8). Once identified, the state routing agency must select routes in accordance with Large Quantity Shipments of Radioactive Materials or an equivalent routing analysis. Adjoining states and localities should be consulted on the impact of proposed alternative routes as a prerequisite of final route selection. Lastly, the states must provide written notice of DOT of any alternative route designation before the routes are deemed effective.

  10. State alternative route designations

    Energy Technology Data Exchange (ETDEWEB)

    1989-07-01

    Pursuant to the Hazardous Materials Transportation Act (HMTA), the Department of Transportation (DOT) has promulgated a comprehensive set of regulations regarding the highway transportation of high-level radioactive materials. These regulations, under HM-164 and HM-164A, establish interstate highways as the preferred routes for the transportation of radioactive materials within and through the states. The regulations also provide a methodology by which a state may select alternative routes. First,the state must establish a state routing agency,'' defined as an entity authorized to use the state legal process to impose routing requirements on carriers of radioactive material (49 CFR 171.8). Once identified, the state routing agency must select routes in accordance with Large Quantity Shipments of Radioactive Materials or an equivalent routing analysis. Adjoining states and localities should be consulted on the impact of proposed alternative routes as a prerequisite of final route selection. Lastly, the states must provide written notice of DOT of any alternative route designation before the routes are deemed effective.

  11. Alternative Fuels: Research Progress

    Directory of Open Access Journals (Sweden)

    Maher A.R. Sadiq Al-Baghdadi

    2013-01-01

    Full Text Available Chapter 1: Pollutant Emissions and Combustion Characteristics of Biofuels and Biofuel/Diesel Blends in Laminar and Turbulent Gas Jet Flames. R. N. Parthasarathy, S. R. Gollahalli Chapter 2: Sustainable Routes for The Production of Oxygenated High-Energy Density Biofuels from Lignocellulosic Biomass. Juan A. Melero, Jose Iglesias, Gabriel Morales, Marta Paniagua Chapter 3: Optical Investigations of Alternative-Fuel Combustion in an HSDI Diesel Engine. T. Huelser, M. Jakob, G. Gruenefeld, P. Adomeit, S. Pischinger Chapter 4: An Insight into Biodiesel Physico-Chemical Properties and Exhaust Emissions Based on Statistical Elaboration of Experimental Data. Evangelos G. Giakoumis Chapter 5: Biodiesel: A Promising Alternative Energy Resource. A.E. Atabani Chapter 6: Alternative Fuels for Internal Combustion Engines: An Overview of the Current Research. Ahmed A. Taha, Tarek M. Abdel-Salam, Madhu Vellakal Chapter 7: Investigating the Hydrogen-Natural Gas Blends as a Fuel in Internal Combustion Engine. ?lker YILMAZ Chapter 8: Conversion of Bus Diesel Engine into LPG Gaseous Engine; Method and Experiments Validation. M. A. Jemni , G. Kantchev , Z. Driss , R. Saaidia , M. S. Abid Chapter 9: Predicting the Combustion Performance of Different Vegetable Oils-Derived Biodiesel Fuels. Qing Shu, ChangLin Yu Chapter 10: Production of Gasoline, Naphtha, Kerosene, Diesel, and Fuel Oil Range Fuels from Polypropylene and Polystyrene Waste Plastics Mixture by Two-Stage Catalytic Degradation using ZnO. Moinuddin Sarker, Mohammad Mamunor Rashid

  12. Alternate fusion concepts as reactors

    International Nuclear Information System (INIS)

    The recent successes of the tokamak concept of controlled fusion have not quenched interest in possible alternatives. This report summarizes a recent study sponsored by the Electric Power Research Institute, which tried to quantify which hoped-for advantages persist when a serious attempt is made to design reactor plants around eight specific alternative concepts (Electron Beam-Heated Solenoid, Elmo Bumpy Torus, Fast Liner, Laser-Heated Solenoid, Linear Theta-Pinch, LINUS, Reversed-Field-Pinch, and Shock-Heated Annulus) addressing key technological issues and economic issues for each concept. The study aimed to isolate the cost drivers for the reactor plant and to compare their capital cost per kilowatt of electricity as well as address the impact of technological difficulty. Results of the study indicated that reactor block costs for the eight plants studied represent a substantially larger fraction of total plant costs than the corresponding fraction for light water reactors; bottom line costs of $ /kWe range over a factor of about two with cost drivers being the physical size of the power producing plasma and the relative magnitudes of the circulating power fraction and the nature of the power circulation. Other cost considerations are also enumerated and the author concludes by noting that one value of the engineering study and cost estimate has been to quantify the relation between physics uncertainty and cost uncertainty

  13. 替代与级联性深度网络与应用研究%Study on the Alternation and Cascade Deep Network

    Institute of Scientific and Technical Information of China (English)

    李森林; 邓小武

    2014-01-01

    神经网络应用中80%~90%采用BP反馈网络,但BP反馈网络存在非约束性、非线性特征,优化模型参数多,计算时间长难收敛,而且优化结果泛化能力不强。2006年深度学习的提出,使神经网络再次成为研究热点。本文提出了一种替代与级联性反馈网络。实验证明替代性反馈神经网络在运算速度、纬度减少、收敛性等方面有一定的提高。%80%to 90%of the neural network applications use BP feedback network, which is non-binding, non-linear, and has many optimization model parameters, long calculating time and difficult convergence, and poor generalization ability of optimiza-tion results. Deep learning proposed in 2006 make neural network become a hot topic once again. This paper presents an alternative and cascade feedback network. Experiments show that the alternative feedback neural network is improved to some extent in com-puting speed, latitude reduction and convergence.

  14. Rapidly alternating combination of cisplatin-based chemotherapy and hyperfractionated accelerated radiotherapy in split course for Stage IIIA and Stage IIIB non-small cell lung cancer: results of a Phase I-II study by the GOTHA group

    Energy Technology Data Exchange (ETDEWEB)

    Alberto, P.; Mermillod, B. [Hopital Cantonal Geneve, Geneva (Switzerland); Mirimanoff, R.O.; Leyvraz, S.; Nagy-Mignotte, H.; Bolla, M.; Wellmann, D.; Moro, D.; Brambilla, E. [Hopital Cantonal Universitaire, Lausanne (Switzerland)

    1995-08-01

    The prognosis of stage III non-small cell lung cancer (NSCLC) can be improved by a combination of radiotherapy (RT) and chemotherapy (CT). In this study, the GOTHA group evaluated the feasibility, tolerance, tumour response, pattern of failure and effect on survival of a combination alternating accelerated hyperfractionated (AH) RT and CT in patients with tumour stage III NSCLC. Toxic effects were leucopenia, nausea and vomiting, mucositis, diarrhoea, alopecia and peripheral neuropathy. Alternating CT and AHRT, as used in this study, were well tolerated and allowed full dose delivery within less than 12 weeks. Initial response was not predictive of survival. The survival curve is encouraging and the 5 year survival is superior to the 5% generally observed with conventionally fractionated radiotherapy. (author).

  15. Green open access in computer science – an exploratory study on author-based self-archiving awareness, practice, and inhibitors

    Directory of Open Access Journals (Sweden)

    Daniel Graziotin

    2014-06-01

    Full Text Available Access to the work of others is something that is too often taken for granted, yet problematic and difficult to be obtained unless someone pays for it. Green and gold open access are claimed to be a solution to this problem. While open access is gaining momentum in some fields, there is a limited and seasoned knowledge about self-archiving in computer science. In particular, there is an inadequate understanding of author-based self-archiving awareness, practice, and inhibitors. This article reports an exploratory study of the awareness of self-archiving, the practice of self-archiving, and the inhibitors of self-archiving among authors in an Italian computer science faculty. Forty-nine individuals among interns, PhD students, researchers, and professors were recruited in a questionnaire (response rate of 72.8%. The quantitative and qualitative responses suggested that there is still work needed in terms of advocating green open access to computer science authors who seldom self-archive and when they do, they often infringe the copyright transfer agreements (CTAs of the publishers. In addition, tools from the open-source community are needed to facilitate author-based self-archiving, which should comprise of an automatic check of the CTAs. The study identified nine factors inhibiting the act of self-archiving among computer scientists. As a first step, this study proposes several propositions regarding author-based self-archiving in computer science that can be further investigated. Recommendations to foster self-archiving in computer science, based on the results, are provided.

  16. Schizophyllum commune has an extensive and functional alternative splicing repertoire

    Science.gov (United States)

    Gehrmann, Thies; Pelkmans, Jordi F.; Lugones, Luis G.; Wösten, Han A. B.; Abeel, Thomas; Reinders, Marcel J. T.

    2016-01-01

    Recent genome-wide studies have demonstrated that fungi possess the machinery to alternatively splice pre-mRNA. However, there has not been a systematic categorization of the functional impact of alternative splicing in a fungus. We investigate alternative splicing and its functional consequences in the model mushroom forming fungus Schizophyllum commune. Alternative splicing was demonstrated for 2,285 out of 12,988 expressed genes, resulting in 20% additional transcripts. Intron retentions were the most common alternative splicing events, accounting for 33% of all splicing events, and 43% of the events in coding regions. On the other hand, exon skipping events were rare in coding regions (1%) but enriched in UTRs where they accounted for 57% of the events. Specific functional groups, including transcription factors, contained alternatively spliced genes. Alternatively spliced transcripts were regulated differently throughout development in 19% of the 2,285 alternatively spliced genes. Notably, 69% of alternatively spliced genes have predicted alternative functionality by loss or gain of functional domains, or by acquiring alternative subcellular locations. S. commune exhibits more alternative splicing than any other studied fungus. Taken together, alternative splicing increases the complexity of the S. commune proteome considerably and provides it with a rich repertoire of alternative functionality that is exploited dynamically. PMID:27659065

  17. Advancing practice relating to SEA alternatives

    Energy Technology Data Exchange (ETDEWEB)

    González, Ainhoa, E-mail: agonzal@tcd.ie [School of Natural Sciences, Trinity College Dublin, Dublin 2 (Ireland); Thérivel, Riki, E-mail: levett-therivel@phonecoop.coop [Levett-Therivel Sustainability Consultants (United Kingdom); Fry, John, E-mail: john.fry@ucd.ie [School of Agriculture and Food Science, University College Dublin, Dublin 4 (Ireland); Foley, Walter, E-mail: walterfoley@gmail.com [School of Geography, Planning and Environmental Policy, University College Dublin, Dublin 4 (Ireland)

    2015-07-15

    Developing and assessing alternatives is a key and central stage to Strategic Environmental Assessment (SEA). However, research has repeatedly reported this stage as one of the most poorly undertaken aspects of the SEA process. Current practice limitations include belated consideration of reasonable alternatives, narrow scope of alternatives that often include unrealistic or retrofitted options, limited stakeholder and public involvement in their identification, assessment and selection, lack of systematic approaches to their assessment and comparison, and inadequate reporting of the ‘storyline’ on how they were identified, what the potential impacts are and why the preferred alternative was selected. These issues have resulted in objections and judicial reviews. On the positive side, a number of good practice case studies enable extraction of key lessons and formulation of a set of general recommendations to advance practice in SEA alternatives. In this paper, practical guidance on the identification and development of alternatives, their assessment and comparison, selection of the preferred option, and documentation of the process and the reasons for selection is provided and discussed to frame good practice approaches. - Highlights: • Alternatives are one of the most poorly completed aspects of Strategic Environmental Assessment. • Current practice limitations need to be addressed to enhance SEA effectiveness. • A set of recommendations are extracted from good practice case studies. • These recommendations can be applied across jurisdictions and sectors and tailored as necessary.

  18. Advancing practice relating to SEA alternatives

    International Nuclear Information System (INIS)

    Developing and assessing alternatives is a key and central stage to Strategic Environmental Assessment (SEA). However, research has repeatedly reported this stage as one of the most poorly undertaken aspects of the SEA process. Current practice limitations include belated consideration of reasonable alternatives, narrow scope of alternatives that often include unrealistic or retrofitted options, limited stakeholder and public involvement in their identification, assessment and selection, lack of systematic approaches to their assessment and comparison, and inadequate reporting of the ‘storyline’ on how they were identified, what the potential impacts are and why the preferred alternative was selected. These issues have resulted in objections and judicial reviews. On the positive side, a number of good practice case studies enable extraction of key lessons and formulation of a set of general recommendations to advance practice in SEA alternatives. In this paper, practical guidance on the identification and development of alternatives, their assessment and comparison, selection of the preferred option, and documentation of the process and the reasons for selection is provided and discussed to frame good practice approaches. - Highlights: • Alternatives are one of the most poorly completed aspects of Strategic Environmental Assessment. • Current practice limitations need to be addressed to enhance SEA effectiveness. • A set of recommendations are extracted from good practice case studies. • These recommendations can be applied across jurisdictions and sectors and tailored as necessary

  19. The Case for Alternative Social Media

    Directory of Open Access Journals (Sweden)

    Robert W. Gehl

    2015-09-01

    Full Text Available What are “alternative social media”? How can we distinguish alternative social media from mainstream social media? Why are social media alternatives important? How do they work? Why do people make them? What do they tell us about contemporary corporate social media and its related phenomena: surveillance, privacy, power, self-expression, and sociality? This essay answers these questions by theorizing alternative social media. The empirical data for this alternative social media theory are drawn from previous work on alternative sites such as Diaspora, rstat.us, Twister, GNU social, and the Dark Web Social Network. These cases are used to build a generalized conceptual framework. However, this article does not solely theorize from these examples, but rather seeks to contextualize and historicize alternative social media theory within larger bodies of work. In addition to generalization from examples, the theory is informed by two threads. The first thread is the work of alternative media scholars such as Nick Couldry, Chris Atton, and Clemencia Rodriguez, who have done the historical and theoretical work to define alternative media. The second thread is a synthesis of works exploring the technical side of contemporary media, coming from new fields such as software studies. The threads and empirical analyses of sites such as Diaspora, Quitter, and rstat.us are combined into a theoretical matrix that can account for the processes and technical infrastructures that comprise social media alternatives and explain why they are distinct from sites such as Facebook, Twitter, and Google, as well as why they are important.

  20. Alternative therapies for postmenopausal women.

    Science.gov (United States)

    Speroff, Leon

    2005-01-01

    Alternative therapies are being used by postmenopausal women in attempts to treat all of the complaints and medical conditions of the menopause. One-fifth of those who take prescription drugs for these indications also take herbal remedies and/or high-dose vitamins, most often without disclosing the fact to the physician. Although studies of alternative therapies are short-term and rarely focused on safety--let alone efficacy--in the long-term, there are many studies spread over the large number of substances involved. More than 130 studies, including meta-analyses, are reviewed in this article under the headings of phytoestrogens, especially from soy; therapies for hot flushes; and preventives for cardiovascular disease, osteoporosis, and breast cancer. Special attention is given to the recently recognized daidzein metabolite equol, and for the sake of completeness there are reviews of the unconventional, but not botanical, treatments estriol, transdermal progesterone, and dehydroepiandrosterone. The total picture produced by conscientious review of the studies is bleak overall, but there seems to be good reason to pursue the possibilities inherent in soy protein with phytoestrogens in populations of women who endogenously produce equol.

  1. Titanium alloys as alternative material for the supercontainer shell in the KBS-3H concept. A preliminary Ti-clay interaction study

    Energy Technology Data Exchange (ETDEWEB)

    Wersin, Paul (Gruner Ltd (Switzerland)); Grolimund, Daniel (Paul Scherrer Institute (Switzerland)); Kumpulainen, Sirpa; Kiviranta, Leena (BandTech Oy (Finland)); Brendle, Jocelyne (University of Mulhouse (France)); Snellman, Margit (Saanio and Riekkola Oy (Finland))

    2010-12-15

    Ti alloys have been proposed as alternative materials to steel for the supercontainer shell surrounding the bentonite buffer in the KBS-3H disposal concept. Ti-based materials display high strength and are known to behave chemically inert under a variety of conditions. This preliminary study addresses the suitability of titanium as supercontainer material with regard to the performance of the clay buffer. Thus, possible titanium-bentonite interactions which may adversely affect the buffer's safety functions are evaluated by means of a literature and a preliminary experimental assessment. Titanium metals display very low corrosion rates (< 1 nm/a) over a large range of pH and Eh conditions. The corrosion behaviour is governed by the low solubility of tetravalent TiO{sub 2} which forms a passive surface corrosion layer under both oxic and reducing conditions. The interactions between titanium and clay have been barely studied so far. Preliminary long-term data obtained by Prof. Olefjord and co-workers from Chalmers (S) in the 1980s (as part of SKB's canister program) suggests similar corrosion rates in compacted bentonite compared to those measured in water, i.e. <1 nm/a. So far, no work on reaction products from this interaction process has been carried out. Even the speciation of Ti in natural clays is uncertain. In principle, four possible reaction products resulting from Ti-clay interactions are possible: (i) Ti sorbed to the clay surface via cation exchange or specific adsorption, (ii) Ti incorporated in the octahedral or tetrahedral clay structure, (iii) Ti precipitated as separate TiO{sub 2} or mixed (Fe, Ti) oxide, (iv) Ti precipitated as separate silicate phase and (v) polymerized as cross-linked TiO{sub 2} units in the interlayer (Ti pillared clay). The latter two transformation products would have the strongest impact on the buffer, but are improbable on the basis of current knowledge. A preliminary batch-type investigation has been carried out

  2. Titanium alloys as alternative material for the supercontainer shell in the KBS-3H concept: A preliminary Ti-clay interaction study

    Energy Technology Data Exchange (ETDEWEB)

    Wersin, P. [Gruner Ltd, Basel (Switzerland); Grolimund, D. [Paul Scherrer Inst., Villigen (Switzerland); Kumpulainen, S.; Kiviranta, L. [B and Tech Oy, Helsinki (Finland); Brendle, J. [Mulhouse Univ. (France); Snellman, M. [Saanio and Riekkola Oy, Helsinki (Finland)

    2011-12-15

    Ti alloys have been proposed as alternative materials to steel for the supercontainer shell surrounding the bentonite buffer in the KBS-3H disposal concept. Ti-based materials display high strength and are known to behave chemically inert under a variety of conditions. This preliminary study addresses the suitability of titanium as supercontainer material with regard to the performance of the clay buffer. Thus, possible titanium-bentonite interactions which may adversely affect the buffer's safety functions are evaluated by means of a literature and a preliminary experimental assessment. Titanium metals display very low corrosion rates (< 1 nm/a) over a large range of pH and Eh conditions. The corrosion behaviour is governed by the low solubility of tetravalent TiO{sub 2} which forms a passive surface corrosion layer under both oxic and reducing conditions. The interactions between titanium and clay have been barely studied so far. Preliminary long-term data obtained by Prof. Olefjord and co-workers from Chalmers (S) in the 1980ies (as part of SKB's canister program) suggests similar corrosion rates in compacted bentonite compared to those measured in water, i.e. 1 nm/a. So far, no work on reaction products from this interaction process has been carried out. Even the speciation of Ti in natural clays is uncertain. In principle, four possible reaction products resulting from Ti-clay interactions are possible: (i) Ti sorbed to the clay surface via cation exchange or specific adsorption, (ii) Ti incorporated in the octahedral or tetrahedral clay structure, (iii) Ti precipitated as separate TiO{sub 2} or mixed (Fe, Ti) oxide, (iv) Ti precipitated as separate silicate phase and (v) polymerized as cross-linked TiO{sub 2} units in the interlayer (Ti pillared clay). The latter two transformation products would have the strongest impact on the buffer, but are improbable on the basis of current knowledge. A preliminary batch-type investigation has been carried out

  3. Titanium alloys as alternative material for the supercontainer shell in the KBS-3H concept: A preliminary Ti-clay interaction study

    International Nuclear Information System (INIS)

    Ti alloys have been proposed as alternative materials to steel for the supercontainer shell surrounding the bentonite buffer in the KBS-3H disposal concept. Ti-based materials display high strength and are known to behave chemically inert under a variety of conditions. This preliminary study addresses the suitability of titanium as supercontainer material with regard to the performance of the clay buffer. Thus, possible titanium-bentonite interactions which may adversely affect the buffer's safety functions are evaluated by means of a literature and a preliminary experimental assessment. Titanium metals display very low corrosion rates (2 which forms a passive surface corrosion layer under both oxic and reducing conditions. The interactions between titanium and clay have been barely studied so far. Preliminary long-term data obtained by Prof. Olefjord and co-workers from Chalmers (S) in the 1980ies (as part of SKB's canister program) suggests similar corrosion rates in compacted bentonite compared to those measured in water, i.e. 1 nm/a. So far, no work on reaction products from this interaction process has been carried out. Even the speciation of Ti in natural clays is uncertain. In principle, four possible reaction products resulting from Ti-clay interactions are possible: (i) Ti sorbed to the clay surface via cation exchange or specific adsorption, (ii) Ti incorporated in the octahedral or tetrahedral clay structure, (iii) Ti precipitated as separate TiO2 or mixed (Fe, Ti) oxide, (iv) Ti precipitated as separate silicate phase and (v) polymerized as cross-linked TiO2 units in the interlayer (Ti pillared clay). The latter two transformation products would have the strongest impact on the buffer, but are improbable on the basis of current knowledge. A preliminary batch-type investigation has been carried out to shed more light on Ticlay interaction processes and on the Ti species resulting from these interactions. Purified MX-80 bentonite was mixed with metallic

  4. Titanium alloys as alternative material for the supercontainer shell in the KBS-3H concept. A preliminary Ti-clay interaction study

    Energy Technology Data Exchange (ETDEWEB)

    Wersin, Paul (Gruner Ltd (Switzerland)); Grolimund, Daniel (Paul Scherrer Institute (Switzerland)); Kumpulainen, Sirpa; Kiviranta, Leena (BandTech Oy (Finland)); Brendle, Jocelyne (University of Mulhouse (France)); Snellman, Margit (Saanio and Riekkola Oy (Finland))

    2010-12-15

    Ti alloys have been proposed as alternative materials to steel for the supercontainer shell surrounding the bentonite buffer in the KBS-3H disposal concept. Ti-based materials display high strength and are known to behave chemically inert under a variety of conditions. This preliminary study addresses the suitability of titanium as supercontainer material with regard to the performance of the clay buffer. Thus, possible titanium-bentonite interactions which may adversely affect the buffer's safety functions are evaluated by means of a literature and a preliminary experimental assessment. Titanium metals display very low corrosion rates (< 1 nm/a) over a large range of pH and Eh conditions. The corrosion behaviour is governed by the low solubility of tetravalent TiO{sub 2} which forms a passive surface corrosion layer under both oxic and reducing conditions. The interactions between titanium and clay have been barely studied so far. Preliminary long-term data obtained by Prof. Olefjord and co-workers from Chalmers (S) in the 1980s (as part of SKB's canister program) suggests similar corrosion rates in compacted bentonite compared to those measured in water, i.e. <1 nm/a. So far, no work on reaction products from this interaction process has been carried out. Even the speciation of Ti in natural clays is uncertain. In principle, four possible reaction products resulting from Ti-clay interactions are possible: (i) Ti sorbed to the clay surface via cation exchange or specific adsorption, (ii) Ti incorporated in the octahedral or tetrahedral clay structure, (iii) Ti precipitated as separate TiO{sub 2} or mixed (Fe, Ti) oxide, (iv) Ti precipitated as separate silicate phase and (v) polymerized as cross-linked TiO{sub 2} units in the interlayer (Ti pillared clay). The latter two transformation products would have the strongest impact on the buffer, but are improbable on the basis of current knowledge. A preliminary batch-type investigation has been carried out

  5. Titanium alloys as alternative material for the supercontainer shell in the KBS-3H concept: A preliminary Ti-clay interaction study

    Energy Technology Data Exchange (ETDEWEB)

    Wersin, P. [Gruner Ltd, Basel (Switzerland); Grolimund, D. [Paul Scherrer Inst., Villigen (Switzerland); Kumpulainen, S.; Kiviranta, L. [B and Tech Oy, Helsinki (Finland); Brendle, J. [Mulhouse Univ. (France); Snellman, M. [Saanio and Riekkola Oy, Helsinki (Finland)

    2011-12-15

    Ti alloys have been proposed as alternative materials to steel for the supercontainer shell surrounding the bentonite buffer in the KBS-3H disposal concept. Ti-based materials display high strength and are known to behave chemically inert under a variety of conditions. This preliminary study addresses the suitability of titanium as supercontainer material with regard to the performance of the clay buffer. Thus, possible titanium-bentonite interactions which may adversely affect the buffer's safety functions are evaluated by means of a literature and a preliminary experimental assessment. Titanium metals display very low corrosion rates (< 1 nm/a) over a large range of pH and Eh conditions. The corrosion behaviour is governed by the low solubility of tetravalent TiO{sub 2} which forms a passive surface corrosion layer under both oxic and reducing conditions. The interactions between titanium and clay have been barely studied so far. Preliminary long-term data obtained by Prof. Olefjord and co-workers from Chalmers (S) in the 1980ies (as part of SKB's canister program) suggests similar corrosion rates in compacted bentonite compared to those measured in water, i.e. 1 nm/a. So far, no work on reaction products from this interaction process has been carried out. Even the speciation of Ti in natural clays is uncertain. In principle, four possible reaction products resulting from Ti-clay interactions are possible: (i) Ti sorbed to the clay surface via cation exchange or specific adsorption, (ii) Ti incorporated in the octahedral or tetrahedral clay structure, (iii) Ti precipitated as separate TiO{sub 2} or mixed (Fe, Ti) oxide, (iv) Ti precipitated as separate silicate phase and (v) polymerized as cross-linked TiO{sub 2} units in the interlayer (Ti pillared clay). The latter two transformation products would have the strongest impact on the buffer, but are improbable on the basis of current knowledge. A preliminary batch-type investigation has been carried out

  6. An alternative form of the Darcy equation

    Directory of Open Access Journals (Sweden)

    Awad Mohamed M.

    2014-01-01

    Full Text Available This study presents an alternative form of the Darcy equation. This alternative form will be presented with the use of Bejan number (Be in the Left Hand Side (LHS of the equation. The main advantage in this alternative form of the Darcy equation is presenting both the Left Hand Side (LHS and the Right Hand Side (RHS as dimensionless quantities. For instance, this is similar to the relation of Fanning friction factor with Reynolds number for Hagen-Poiseuille flow (fully developed laminar flow in a circular pipe.

  7. Characterization of alternative FBR development strategies

    International Nuclear Information System (INIS)

    Near-term decisions regarding the nature and place of the FBR development program must be made. This study is part of a larger program designed to provide the Department of Energy (DOE) with imformation that can be used to make strategic programmatic decisions. The focus of this report is the description of alternative approaches for developing the FBR and the quantification of the duration and cost of each alternative. The time frames of the alternative approaches are investigated in companion reports (White 1981 and Fraley 1981). The results of these analyses will be described in a summary report

  8. Potential of renewable and alternative energy sources

    Science.gov (United States)

    Konovalov, V.; Pogharnitskaya, O.; Rostovshchikova, A.; Matveenko, I.

    2015-11-01

    The article deals with application potential of clean alternative renewable energy sources. By means of system analysis the forecast for consumption of electrical energy in Tomsk Oblast as well as main energy sources of existing energy system have been studied up to 2018. Engineering potential of renewable and alternative energy sources is evaluated. Besides, ranking in the order of their efficiency descending is performed. It is concluded that Tomsk Oblast has high potential of alternative and renewable energy sources, among which the most promising development perspective is implementation of gasification stations to save fuel consumed by diesel power stations as well as building wind-power plants.

  9. Alternative Energy Development and China's Energy Future

    Energy Technology Data Exchange (ETDEWEB)

    Zheng, Nina; Fridley, David

    2011-06-15

    In addition to promoting energy efficiency, China has actively pursued alternative energy development as a strategy to reduce its energy demand and carbon emissions. One area of particular focus has been to raise the share of alternative energy in China’s rapidly growing electricity generation with a 2020 target of 15% share of total primary energy. Over the last ten years, China has established several major renewable energy regulations along with programs and subsidies to encourage the growth of non-fossil alternative energy including solar, wind, nuclear, hydro, geothermal and biomass power as well as biofuels and coal alternatives. This study thus seeks to examine China’s alternative energy in terms of what has and will continue to drive alternative energy development in China as well as analyze in depth the growth potential and challenges facing each specific technology. This study found that despite recent policies enabling extraordinary capacity and investment growth, alternative energy technologies face constraints and barriers to growth. For relatively new technologies that have not achieved commercialization such as concentrated solar thermal, geothermal and biomass power, China faces technological limitations to expanding the scale of installed capacity. While some alternative technologies such as hydropower and coal alternatives have been slowed by uneven and often changing market and policy support, others such as wind and solar PV have encountered physical and institutional barriers to grid integration. Lastly, all alternative energy technologies face constraints in human resources and raw material resources including land and water, with some facing supply limitations in critical elements such as uranium for nuclear, neodymium for wind and rare earth metals for advanced solar PV. In light of China’s potential for and barriers to growth, the resource and energy requirement for alternative energy technologies were modeled and scenario analysis

  10. Alternate fuels; Combustibles alternos

    Energy Technology Data Exchange (ETDEWEB)

    Romero Paredes R, Hernando; Ambriz G, Juan Jose [Universidad Autonoma Metropolitana. Iztapalapa (Mexico)

    2003-07-01

    In the definition and description of alternate fuels we must center ourselves in those technological alternatives that allow to obtain compounds that differ from the traditional ones, in their forms to be obtained. In this article it is tried to give an overview of alternate fuels to the conventional derivatives of petroleum and that allow to have a clear idea on the tendencies of modern investigation and the technological developments that can be implemented in the short term. It is not pretended to include all the tendencies and developments of the present world, but those that can hit in a relatively short term, in accordance with agreed with the average life of conventional fuels. Nevertheless, most of the conversion principles are applicable to the spectrum of carbonaceous or cellulosic materials which are in nature, are cultivated or wastes of organic origin. Thus one will approach them in a successive way, the physical, chemical and biological conversions that can take place in a production process of an alternate fuel or the same direct use of the fuel such as burning the sweepings derived from the forests. [Spanish] En la definicion y descripcion de combustibles alternos nos debemos centrar en aquellas alternativas tecnologicas que permitan obtener compuestos que difieren de los tradicionales, al menos en sus formas de ser obtenidos. En este articulo se pretende dar un panorama de los combustibles alternos a los convencionales derivados del petroleo y que permita tener una idea clara sobre las tendencias de la investigacion moderna y los desarrollos tecnologicos que puedan ser implementados en el corto plazo. No se pretende abarcar todas las tendencias y desarrollos del mundo actual, sino aquellas que pueden impactar en un plazo relativamente corto, acordes con la vida media de los combustibles convencionales. Sin embargo, la mayor parte de los principios de conversion son aplicables al espectro de materiales carbonaceos o celulosicos los cuales se

  11. Alternate fusion concepts

    International Nuclear Information System (INIS)

    This review summarizes the status of alternate fusion concepts and plans for their future. The concepts selected for review are those employing electromagnetic confinement for which there have been reasonable predictions of net energy gain from pure fusion and which have shown significant recent development or are the subjects of ongoing international activity. They include advanced tokamaks, stellarators, the spherical torus, reversed-field pinch and dense z-field pinch devices, field reversed configuration, and spheromaks. In addition, an overall view of the status of each concept with respect to achieving ignition and to reactor designs is presented

  12. Alternate transportation system

    Science.gov (United States)

    Zertuche, Tony; Mckinnie, James

    1988-01-01

    Three missions have been identified by NASA for a Space Shuttle-supplementing Alternate Transportation System (ATS) encompassing combinations of booster vehicles, crew modules, and service modules: (1) to achieve manned access to orbit for Space Station crew rotation every 90 days, (2) the lofting of a logistics module resupplying the Space Station every 180 days, and (3) the simultaneous launch of both crews and logistics to the Space Station. A reentry glider is considered, in conjunction with the Space Shuttle's unmanned cargo version and the Apollo manned capsule, as an important ATS element. The Titan IV/NUS is used as a booster.

  13. Polyphase alternating codes

    OpenAIRE

    M. Markkanen; Vierinen, J.; Markkanen, J.

    2007-01-01

    We present a new class of alternating codes. Instead of the customary binary phase codes, the new codes utilize either p or p–1 phases, where p is a prime number. The first class of codes has code length pm, where m is a positive integer, the second class has code length p–1. We give an actual construction algorithm, and explain the principles behind it. We ...

  14. Polyphase alternating codes

    Directory of Open Access Journals (Sweden)

    M. Markkanen

    2008-08-01

    Full Text Available We present a new class of alternating codes. Instead of the customary binary phase codes, the new codes utilize either p or p–1 phases, where p is a prime number. The first class of codes has code length pm, where m is a positive integer, the second class has code length p–1. We give an actual construction algorithm, and explain the principles behind it. We handle a few specific examples in detail. The new codes offer an enlarged collection of code lengths for radar experiments.

  15. Study on the technical and economic viability of vehicles and alternative fuels; Estudo de viabilidade tecnica e economica de veiculos e combustiveis alternativos

    Energy Technology Data Exchange (ETDEWEB)

    Lima, Bruno Carvalho Alves de; Oliveira, Paulo Leandro de; Almeida, Silvio Carlos Anibal de [Universidade Federal, Rio de Janeiro, RJ (Brazil). Dept. de Engenharia Mecanica]. E-mail: baiano@labma.ufrj.br; silvio@serv.com.ufrj.br

    1999-07-01

    This paper presents a resume of the research project under development in the COPPE/UFRJ, Brazil. This project compares different vehicle types and alternative fuels, considering the following parameters: average hourly consumption, level of total hydrocarbons, NO{sub x} and CO emissions, operation and maintenance costs. The following vehicle types are analysed: conventional using gasoline, vehicles using ethanol, natural gas and liquid petroleum gas, electric, hybrid electric, electric with fuel cells, electric with fuel cells and gasoline reformation and vehicles using methanol. The simulation packet ADVISOR 2.1 has been used for analysis of the emission made available by the US DOE. For the analysis of the performance/consumption, a code developed by the authors has been used.

  16. Combined chemotherapy and radiotherapy in diffuse large cell immunoblastic lymphoma: a phase II study of CHOP/bleomycin/methotrexate alternating with ifosfamide/methotrexate/etoposide

    International Nuclear Information System (INIS)

    The clinical outcome of 23 patients with high grade diffuse large cell immunoblastic lymphoma (Working Formulation, category H) treated by an intensive shortened schedule regimen of chemotherapy is described. Alternating cycles of cyclophosphamide, doxorubicin, vincristine, bleomycin and prednisolone, and ifosfamide, etoposide and methotrexate were given over an 18-week (range 16.0-20.8) period. External beam radiotherapy was administered as consolation therapy to sites of original bulky disease in 17 patients. Treatment was well tolerated, though there were two toxic deaths. A 90% response rate was obtained. Sixteen of 18 patients followed for a minimum of 36 months are alive and in complete remission, representing a disease free survival of 69.5%; two further patients are alive following autologous bone marrow transplant. The 3-year disease free survival was 73% (±9%) and the overall 3-year survival 78% (±9%). (author)

  17. Hypnosis and Local Anesthesia for Dental Pain Relief-Alternative or Adjunct Therapy?-A Randomized, Clinical-Experimental Crossover Study.

    Science.gov (United States)

    Wolf, Thomas Gerhard; Wolf, Dominik; Callaway, Angelika; Below, Dagna; d'Hoedt, Bernd; Willershausen, Brita; Daubländer, Monika

    2016-01-01

    This prospective randomized clinical crossover trial was designed to compare hypnosis and local anesthesia for experimental dental pain relief. Pain thresholds of the dental pulp were determined. A targeted standardized pain stimulus was applied and rated on the Visual Analogue Scale (0-10). The pain threshold was lower under hypnosis (58.3 ± 17.3, p < .001), maximal (80.0) under local anesthesia. The pain stimulus was scored higher under hypnosis (3.9 ± 3.8) than with local anesthesia (0.0, p < .001). Local anesthesia was superior to hypnosis and is a safe and effective method for pain relief in dentistry. Hypnosis seems to produce similar effects observed under sedation. It can be used in addition to local anesthesia and in individual cases as an alternative for pain control in dentistry. PMID:27585724

  18. Hypnosis and Local Anesthesia for Dental Pain Relief-Alternative or Adjunct Therapy?-A Randomized, Clinical-Experimental Crossover Study.

    Science.gov (United States)

    Wolf, Thomas Gerhard; Wolf, Dominik; Callaway, Angelika; Below, Dagna; d'Hoedt, Bernd; Willershausen, Brita; Daubländer, Monika

    2016-01-01

    This prospective randomized clinical crossover trial was designed to compare hypnosis and local anesthesia for experimental dental pain relief. Pain thresholds of the dental pulp were determined. A targeted standardized pain stimulus was applied and rated on the Visual Analogue Scale (0-10). The pain threshold was lower under hypnosis (58.3 ± 17.3, p hypnosis (3.9 ± 3.8) than with local anesthesia (0.0, p hypnosis and is a safe and effective method for pain relief in dentistry. Hypnosis seems to produce similar effects observed under sedation. It can be used in addition to local anesthesia and in individual cases as an alternative for pain control in dentistry.

  19. The Role of Alternating Bilateral Stimulation in Establishing Positive Cognition in EMDR Therapy: A Multi-Channel Near-Infrared Spectroscopy Study

    Science.gov (United States)

    Amano, Tamaki; Toichi, Motomi

    2016-01-01

    Eye movement desensitisation and reprocessing (EMDR) is a standard method for treating post-traumatic stress disorder. EMDR treatment consists of desensitisation and resource development and installation (RDI) stages. Both protocols provide a positive alternating bilateral stimulation (BLS). The effect of desensitisation with BLS has been elucidated. However, a role for BLS in RDI remains unknown. Therefore, it is important to measure feelings as subjective data and physiological indicators as objective data to clarify the role of BLS in RDI. RDI was administered to 15 healthy volunteer subjects who experienced pleasant memories. Their oxygenated haemoglobin concentration ([oxy-Hb]), a sensitive index of brain activity, was measured from the prefrontal cortex (PFC) to the temporal cortex using multi-channel near-infrared spectroscopy during recall of a pleasant memory with or without BLS. The BLS used was alternating bilateral tactile stimulation with a vibration machine. The psychological evaluation suggested that RDI was successful. The results showed that, compared with non-BLS conditions, accessibility was increased and subjects were more relaxed under BLS conditions. A significant increase in [oxy-Hb] was detected in the right superior temporal sulcus (STS), and a decrease in the wide bilateral areas of the PFC was observed in response to BLS. The significant BLS-induced activation observed in the right STS, which is closely related to memory representation, suggests that BLS may help the recall of more representative pleasant memories. Furthermore, the significant reduction in the PFC, which is related to emotion regulation, suggests that BLS induces relaxation and comfortable feelings. These results indicate an important neural mechanism of RDI that emotional processing occurred rather than higher cognitive processing during this stage. Considering the neuroscientific evidence to date, BLS in RDI may enhance comfortable feelings about pleasant memories

  20. Work at sea: a study of sleep, and of circadian rhythms in physiological and psychological functions, in watchkeepers on merchant vessels. VI. A sea trial of an alternative watchkeeping system for the merchant marine.

    Science.gov (United States)

    Fletcher, N; Colquhoun, W P; Knauth, P; De Vol, D; Plett, R

    1988-01-01

    A trial of an alternative to the traditional 4-on/8-off watchkeeping system was made on a container ship during a round trip from Europe to the Far East. The three navigating officers on the ship operated the new system, which involved "compressed" working hours with a long unbroken period of rest, during two sections of the voyage, one of which included six stops at ports. Despite unforeseen problems arising mainly from these stops, questionnaire responses concerning the new system were not altogether unfavourable to it, and daily records kept by the officers gave some support to the hypothesis that sleep would be better than under the traditional system. However, a number of difficulties were encountered; these are discussed in relation to the design of future studies of alternative watchkeeping systems. PMID:3198284