WorldWideScience

Sample records for alpha absorption systems

  1. A Faraday rotation search for magnetic fields in quasar damped Ly alpha absorption systems

    Science.gov (United States)

    Oren, Abraham L.; Wolfe, Arthur M.

    1995-01-01

    We present the results of a Faraday rotation survey of 61 radio-bright QSOs conducted at the National Radio Astronomy Observatory (NRAO) Very Large Array (VLA). The Galactic contribution to the Faraday rotation is estimated and subtracted to determine the extragalactic rotation measure (RRM) for each source. Eleven of these QSOs are known to exhibit damped Ly alpha absorption. The rate of incidence of significant Faraday rotation of these 11 sources is compared to the remaining 50 and is found to be higher at the 99.8% confidence level. However, as this is based upon only two detections of Faraday rotation in the damped Ly alpha sample, the result is only tentative. If the two detections in the damped Ly alpha sample are dug to the absorbing systems, then the inferred rotation measure induced by these systems is roughly 250 rad/sq m. The two detections were for the two lowest redshift absorbers in the sample. We find that a rotation measure of 250 rad/sq m would have gone undetected for any other absorber in the damped Ly alpha sample due to the 1/(1 + 2) squared dilution of the observed RRM with redshift. Thus the data are consistent with, but do not prove, the hypothesis that Faraday rotation is a generic property of damped Ly alpha absorbers. We do not confirm the suggestion that the amplitude of RRMs increases with redshift. Rather, the data are consistent with no redshift evolution. We find that the uncertainty in the estimation of the Galactic rotation measure (GRM) is a more serious problem than previously realized for extra-galactic Faraday rotation studies of QSO absorbers. A careful analysis of current methods for estimating GRM indicate that it can be determined to an accuracy of about 15 - 20 rad/sq m. Previous studies underestimated this uncertainty by more than a factor of 2. Due to this uncertainty, rotation measures such as we suspect are associated with damped Ly alpha absorption systems can only be detected at redshifts less than z approximately

  2. Absorption of lower hybrid waves by alpha particles in ITER

    International Nuclear Information System (INIS)

    Imbeaux, F.; Peysson, Y.; Eriksson, L.G.

    2003-01-01

    Absorption of lower hybrid (LH) waves by alpha particles may reduce significantly the current drive efficiency of the waves in a reactor or burning plasma experiment. This absorption is quantified for ITER using the ray-tracing+2D relativistic Fokker-Planck code Delphine. The absorption is calculated as a function of the superthermal alpha particle density, which is constant in these simulations, for two candidate frequencies for the LH system of ITER. Negligible absorption by alpha particles at 3.7 GHz requires n(alpha,supra) = 7.5 10 16 m -3 , while no significant impact on the driven current is found at 5 GHz, even if n(alpha,supra) = 1.5 10 18 m -3 . (authors)

  3. Comparison of vascular alpha(1)-adrenoceptor antagonism of tamsulosin in oral controlled absorption system (OCAS) and modified release (MR) formulations

    NARCIS (Netherlands)

    Michel, M. C.; Korstanje, C.; Krauwinkel, W.; Shear, M.; Davies, J.; Quartel, A.

    2005-01-01

    Objective: The cardiovascular a-l-adrenoceptor (AR) antagonism of the new oral controlled absorption system (OCAS) 0.4 mg tablet formulation of tamsulosin was compared with that of the modified release (MR) 0.4 mg capsule formulation in healthy male volunteers after a single dose in the fasted

  4. Technical Basis for the Use of Alpha Absorption Corrections on RCF Gross Alpha Data

    International Nuclear Information System (INIS)

    Ceffalo, G.M.

    1999-01-01

    This document provides the supporting data and rationale for making absorption corrections to gross alpha data to correct alpha data for loss due to absorption in the sample matrix. For some time there has been concern that the gross alpha data produced by the Environmental Restoration Contractor Radiological Counting Facility, particularly gross alpha analysis on soils, has been biased toward low results, as no correction for self-absorption was applied to the counting data. The process was investigated, and a new methodology for alpha self-absorption has been developed

  5. Absorption heat pump system

    Science.gov (United States)

    Grossman, G.

    1982-06-16

    The efficiency of an absorption heat pump system is improved by conducting liquid from a second stage evaporator thereof to an auxiliary heat exchanger positioned downstream of a primary heat exchanger in the desorber of the system.

  6. Optical absorption measurement system

    International Nuclear Information System (INIS)

    Draggoo, V.G.; Morton, R.G.; Sawicki, R.H.; Bissinger, H.D.

    1989-01-01

    This patent describes a non-intrusive method for measuring the temperature rise of optical elements under high laser power optical loading to determine the absorption coefficient. The method comprises irradiating the optical element with a high average power laser beam, viewing the optical element with an infrared camera to determine the temperature across the optical element and calculating the absorption of the optical element from the temperature

  7. Damped Lyman-alpha absorption by disk galaxies with large redshifts. III. Intermediate-resolution spectroscopy

    International Nuclear Information System (INIS)

    Turnshek, D.A.; Wolfe, A.M.; Lanzetta, K.M.; Briggs, F.H.; Cohen, R.D.

    1989-01-01

    New intermediate-resolution spectroscopy for six members of a sample of 68 moderate- to high-redshift QSOs is presented. Evidence is reported which indicates that seven strong absorption features in the QSO spectra are due to damped Ly-alpha absorption. A standard curve-of-growth analysis on five of the damped systems is performed, and relevant properties are tabulated and discussed. Six of the seven damped Ly-alpha systems have H I column densities of 2 x 10 to the 20th/sq cm or larger, while the remaining system has an H I column density of about 10 to the 20th/sq cm. It is suggested that damped Ly-alpha systems arise when a sight line intercepts a high-redshift protogalaxy disk containing a quiescent cloud component characterized by high column density and low effective velocity dispersion. At the same time, the sight line usually intercepts a broader turbulent component, which is identified as the halo, characterized by much lower column density and higher effective velocity dispersion. 42 refs

  8. Alpha-monitoring system

    International Nuclear Information System (INIS)

    Dincklage, R.D. von

    1982-01-01

    A continuously operating and fast system for the monitoring of radiactive materials is outlined. Its application to nuclear technology particularly to reprocessing is emphasized. Using high-resolution α-ray spectrocopy and the gas-jet method for the rapid transportation of the radionuclides to the solid state detectors makes detection limits as low as 0.2 μg/cm 3 for Pu-239 feasible. (orig.)

  9. Absorption-heat-pump system

    Science.gov (United States)

    Grossman, G.; Perez-Blanco, H.

    1983-06-16

    An improvement in an absorption heat pump cycle is obtained by adding adiabatic absorption and desorption steps to the absorber and desorber of the system. The adiabatic processes make it possible to obtain the highest temperature in the absorber before any heat is removed from it and the lowest temperature in the desorber before heat is added to it, allowing for efficient utilization of the thermodynamic availability of the heat supply stream. The improved system can operate with a larger difference between high and low working fluid concentrations, less circulation losses, and more efficient heat exchange than a conventional system.

  10. Quasi-linear absorption of lower hybrid waves by fusion generated alpha particles

    International Nuclear Information System (INIS)

    Barbato, E.; Santini, F.

    1991-01-01

    Lower hybrid waves are expected to be used in a steady state reactor to produce current and to control the current profile and the stability of internal modes. In the ignition phase, however, the presence of energetic alpha particles may prevent wave-electron interaction, thus reducing the current drive efficiency. This is due to the very high birth energy of the alpha particles that may absorb much of the lower hybrid wave power. This unfavourable effect is absent at high frequencies (∼ 8 GHz for typical reactor parameters). Nevertheless, because of the technical difficulties involved in using such high frequencies, it is very important to investigate whether power absorption by alpha particles would be negligible also at relatively low frequencies. Such a study has been carried out on the basis of the quasi-linear theory of wave-alpha particle interaction, since the distortion of the alpha distribution function may enhance the radiofrequency absorption above the linear level. New effects have been found, such as local alpha concentration and acceleration. The model for alpha particles is coupled with a 1-D deposition code for lower hybrid waves to calculate the competition in the power absorption between alphas and electrons as the waves propagate into the plasma core for typical reactor (ITER) parameters. It is shown that at a frequency as low as 5 GHz, power absorption by alpha particles is negligible for conventional plasma conditions and realistic alpha particle concentrations. In more ''pessimistic'' and severe conditions, negligible absorption occurs at 6 GHz. (author). 19 refs, 11 figs, 2 tabs

  11. Alpha-lactalbumin and casein-glycomacropeptide do not affect iron absorption from formula in healthy term infants

    Science.gov (United States)

    Iron absorption from infant formula is relatively low. Alpha-lactalbumin and casein-glycomacropeptide have been suggested to enhance mineral absorption. We therefore assessed the effect of alpha-lactalbumin and casein-glycomacropeptide on iron absorption from infant formula in healthy term infants. ...

  12. Target characterization by PIXE, alpha spectrometry and X-ray absorption

    International Nuclear Information System (INIS)

    Kheswa, N.Y.; Papka, P.; Pineda-Vargas, C.A.; Newman, R.T.

    2011-01-01

    We report on the thickness and homogeneity characterization of thin metallic targets of Zr-96 by means of alpha absorption spectrometry, Particle Induced X-ray Emission (PIXE) and X-ray absorption. The target thicknesses determined by means of the above mentioned methods are critically compared. The thicknesses were determined before and after irradiation with a 70 MeV beam of 14 N ions.

  13. Cosmological Evolution of QSO Absorption Systems

    Science.gov (United States)

    Stengler-Larrea, Erik

    1995-08-01

    First, the evolution with cosmic time of the hydrogen clouds which produce the Lyman-alpha absorption lines is studied in dependence on the strength of these lines. From the analysis it is concluded that the results show no evidence of a dependence in the sense of stronger lines evolving faster, although for the resolution at which the used observations were done, it can not be ruled out. Within the same analysis, a distribution of the Doppler parameter of the lines was obtained, with large values and a wide spread. This parameter being an indicator of the gas temperature, this result is in accordance with high temperatures and, consequently, large ionised fractions and a large fraction of the baryonic matter of the universe being associated with these clouds. However, recent high resolution studies seem to reveal that much lower temperatures are characteristic of the clouds. The main content of this thesis, however, focuses on the redshift evolution of the absorbing systems producing absorption at the Lyman limit and of the amount of CIV producing CIV absorption lines. Regarding the CIV absorbers, previous predictions on the effects underlying their redshift distribution pointed to an increase with redshift of the absorbing column densities. In this thesis the first direct measurements of such column densities by profile fitting of a large number of absorption systems (73) are presented, confirming the predictions of a decrease of at least a factor of 3 between z=1.5 and z=3.0. The study on the evolution of Lyman limit absorption systems (LLSs) puts an end to previous discrepancies between the results of different groups. Both a smooth single power law dependence of the LLS number density on redshift indicating no evolution in number density for 0.4 Team of the HST Key Project on QSO absorption lines, and in particular to estimate the necessary exposure times, the magnitudes of several of these objects had to be re-measured. The acquisition of their images and the

  14. Diagnosing the reionization of the universe - The absorption spectrum of the intergalactic medium and Lyman alpha clouds

    Science.gov (United States)

    Giroux, Mark L.; Shapiro, Paul R.

    1991-01-01

    The thermal and ionization evolution of a uniform intergalactic medium composed of H and He and undergoing reionization is studied. The diagnosis of the metagalactic ionizing radiation background at z of about three using metal line ratios for Lyman limit quasar absorption line systems is addressed. The use of the He II Gunn-Peterson effect to diagnose the reionization source and/or nature of the Hy-alpha forest clouds is considered.

  15. Integrated minicomputer alpha analysis system

    International Nuclear Information System (INIS)

    Vasilik, D.G.; Coy, D.E.; Seamons, M.; Henderson, R.W.; Romero, L.L.; Thomson, D.A.

    1978-01-01

    Approximately 1,000 stack and occupation air samples from plutonium and uranium facilities at LASL are analyzed daily. The concentrations of radio-nuclides in air are determined by measuring absolute alpha activities of particulates collected on air sample filter media. The Integrated Minicomputer Pulse system (IMPULSE) is an interface between many detectors of extremely simple design and a Digital Equipment Corporation (DEC) PDP-11/04 minicomputer. The detectors are photomultiplier tubes faced with zinc sulfide (ZnS). The average detector background is approximately 0.07 cpm. The IMPULSE system includes two mainframes, each of which can hold up to 64 detectors. The current hardware configuration includes 64 detectors in one mainframe and 40 detectors in the other. Each mainframe contains a minicomputer with 28K words of Random Access Memory. One minicomputer controls the detectors in both mainframes. A second computer was added for fail-safe redundancy and to support other laboratory computer requirements. The main minicomputer includes a dual floppy disk system and a dual DEC 'RK05' disk system for mass storage. The RK05 facilitates report generation and trend analysis. The IMPULSE hardware provides for passage of data from the detectors to the computer, and for passage of status and control information from the computer to the detector stations

  16. Iota-dependent resonance absorption in the optical model description of alpha particle elastic scattering

    International Nuclear Information System (INIS)

    Chyla, K.; Jarczyk, L.; Maciuk, B.; Zipper, W.

    1976-01-01

    Alpha particle scattering from 28 Si has been studied at five bombarding energies from 23.5 to 28.5 MeV. iota-dependent resonance absorption has been introduced to the optical model analysis of 28 Si (α,β) 28 Si reaction. (author)

  17. Low redshift Lyman alpha absorption lines and the dark matter halos of disk galaxies

    Science.gov (United States)

    Maloney, Philip

    1993-01-01

    Recent observations using the Hubble Space Telescope of the z = 0.156 QSO 3C 273 have discovered a surprisingly large number of Ly-alpha absorption lines. In particular, Morris et al. found 9 certain and 7 possible Ly-alpha lines with equivalent widths above 25 mA. This is much larger (by a factor of 5-10) than the number expected from extrapolation of the high-redshift behavior of the Ly-alpha forest. Within the context of pressure-confined models for the Ly-alpha clouds, this behavior can be understood if the ionizing background declines sharply between z is approximately 2 and z is approximately 0. However, this requires that the ionizing photon flux drop as rapidly as the QSO volume emissivity; moreover, the absorbers must have a space density n(sub O) is approximately 2.6(N/10)h/((D/100 kpc)(sup 2)) Mpc(sup -3) where D is the present-day diameter of the absorbers. It is somewhat surprising that such necessarily fragile objects could have survived in such numbers to the present day. It is shown that it is plausible that the atomic hydrogen extents of spiral and irregular galaxies are large enough to produce the observed number of Ly-alpha absorption lines toward 3C 273, and that the neutral column densities and doppler b-values expected under these conditions fall in the range found by Morris et al. (1991).

  18. Uniform semiclassical approximation for absorptive scattering systems

    International Nuclear Information System (INIS)

    Hussein, M.S.; Pato, M.P.

    1987-07-01

    The uniform semiclassical approximation of the elastic scattering amplitude is generalized to absorptive systems. An integral equation is derived which connects the absorption modified amplitude to the absorption free one. Division of the amplitude into a diffractive and refractive components is then made possible. (Author) [pt

  19. Self-absorption alpha particle factor in water: interest in the monitoring of specific military sites

    International Nuclear Information System (INIS)

    Cazoulat, A.; Lecompte, Y.; Bohand, S.; Gerasimo, P.

    2007-01-01

    Self-absorption alpha particle factor validation in water: Interest in the monitoring of specific military sites. The population internal intake prevention by radionuclides present in water needs to monitor the radioactive Level of this water. The French public health legislation introduces four radiological parameters for monitoring water, such as the gross alpha radioactivity. Regarding the alpha particle characteristics, a self-absorption factor has to be established beforehand, not to underestimate the real alpha radioactivity in water samples. The aim of this paper is to describe the procedure used by the laboratory of the French army radioprotection service to determine this f factor, which depends on the water residue mass m after evaporation. The relation is f = 0.0253 m + 1.2813. This formula can be employed for such waters used in this experiment and for masses between 0 and 100 mg. The uncertainty associated is about 11% (k = 2). Some water monitoring examples are given. It is specially the case of depleted uranium shells experiment centres, localized in Gramat and Bourges. (authors)

  20. Correction for the absorption of plutonium alpha particles in filter paper used for dust sampling

    Energy Technology Data Exchange (ETDEWEB)

    Simons, J G

    1956-01-01

    This sample of air-borne dust collected on a filter paper when laboratory air is monitored for plutonium with the 1195 portable dust sampling unit may be regarded, for counting purposes, as a thick source with a non-uniform distribution of alpha-active plutonium. Experiments have been carried out to determine a correction factor to be applied to the observed count on the filter paper sample to correct for internal absorption in the paper and on the dust layer. From the results obtained it is recommended that a correction factor of 2 be used.

  1. Constraining the Intergalactic and Circumgalactic Media with Lyman-Alpha Absorption

    Science.gov (United States)

    Sorini, Daniele; Onorbe, Jose; Hennawi, Joseph F.; Lukic, Zarija

    2018-01-01

    Lyman-alpha (Ly-a) absorption features detected in quasar spectra in the redshift range 02Mpc, the simulations asymptotically match the observations, because the ΛCDM model successfully describes the ambient IGM. This represents a critical advantage of studying the mean absorption profile. However, significant differences between the simulations, and between simulations and observations are present on scales 20kpc-2Mpc, illustrating the challenges of accurately modeling and resolving galaxy formation physics. It is noteworthy that these differences are observed as far out as ~2Mpc, indicating that the `sphere-of-influence' of galaxies could extend to approximately ~20 times the halo virial radius (~100kpc). Current observations are very precise on these scales and can thus strongly discriminate between different galaxy formation models. I demonstrate that the Ly-a absorption profile is primarily sensitive to the underlying temperature-density relationship of diffuse gas around galaxies, and argue that it thus provides a fundamental test of galaxy formation models. With near-future high-precision observations of Ly-a absorption, the tools developed in my thesis set the stage for even stronger constraints on models of galaxy formation and cosmology.

  2. Systemic Absorption of Nanomaterials by Oral Exposure

    DEFF Research Database (Denmark)

    Binderup, Mona-Lise; Bredsdorff, Lea; Beltoft, Vibe Meister

    This report and accompanying database systematically evaluates the reliability and relevance of the existing scientific literature regarding systemic absorption of nanomaterials by oral exposure and makes specific recommendations for future testing approaches.......This report and accompanying database systematically evaluates the reliability and relevance of the existing scientific literature regarding systemic absorption of nanomaterials by oral exposure and makes specific recommendations for future testing approaches....

  3. Laboratory system for alpha particle spectroscopy

    International Nuclear Information System (INIS)

    Dean, J.R.; Chiu, N.W.

    1987-03-01

    An automated alpha particle spectroscopy system has beeen designed and fabricated. It consists of two major components, the automatic sample changer and the controller/data acquisition unit. It is capable of unattended analysis of ten samples for up to 65,000 seconds per sample

  4. Lymphatic absorption of hypolipidemic compound, 1-O-[p-(myristyloxy)-alpha-methylcinnamoyl] glycerol (LK-903).

    Science.gov (United States)

    Sugihara, J; Furuuchi, S

    1988-02-01

    The intestinal absorption process of 1-O-[p-(myristyloxy)-alpha-methylcinnamoyl] glycerol (LK-903), a new hypolipidemic compound, was studied in rats. When 3H-LK-903 or 3H-LKA [3H-p- (myristyloxy)-alpha-methyl cinnamic acid], labeled at the cinnamic acid moiety, or 14C-LK-903, labeled at the glycerol moiety, were administered orally to thoracic duct-cannulated rats at a dose of 0.233 mmol/kg, 31.1, 6.7 and 18.1% of the dose, respectively, appeared in the lymph within 24 h. In this case, radioactive compounds in the lymph lipids consisted of LKA (radioactivity was not detected in the fraction of LKA with 14C-LK-903), LK-903, diglyceride analogues and triglyceride analogues. The percentages of the triglyceride analogues were the highest, followed by the diglyceride analogues. On the other hand, when doubly labeled LK-903 (3H/14C = 1, corrected ratio) was administered orally, the values of 3H/14C for the monoglyceride, diglyceride and triglyceride analogues in the lymph were 1.2-1.5, 1.7-1.9 and 1.9-2.7, respectively. The lymphatic absorption of LK-903 was stimulated by the presence of lecithin but inhibited by a high dose of triolein. The results indicated that (1) LK-903 formed micelles in the intestine, (2) a large part of LK-903 was absorbed as such, (3) a part of LK-903 was hydrolyzed in the intestinal mucosa, and (4) a part of LKA formed by hydrolysis was again utilized to synthesize the higher glycerides and absorbed via the lymphatic absorption route for lipids.

  5. Study of interplanetary hydrogen from Lyman alpha emission and absorption determination

    International Nuclear Information System (INIS)

    Cazes, Serge.

    1979-09-01

    The purpose of the work submitted in this paper is to contribute to the study of interplanetary hydrogen from Lyman alpha emission and absorption measurements, carried out on board the D2A, OSO-8 and Copernicus satellites. This study, which was undertaken from the D2A satellite, moved us to study the interplanetary environment as from observations made from the following experiments placed on board the OSO-8 and Copernicus satellites. The experiment set up on board the OSO-8 satellite made it possible to obtain the profile of the solar alpha Lyman emission. An absorption profile was observed for the first time on these profiles and this made it possible to attribute them to interplanetary hydrogen and enabled us to make a direct and local determination of the solar ionization rate. - The spectrometer set up on board Copernicus made it possible to obtain the emission spectrum of the interplanetary environment at the same time as the geocorona. The overall velocity of the interplanetary environment was deduced from the Doppler shift between the two spectra. In the first part, the principle of the REA and POLAR experiments is recalled but only the REA experiment is described in detail, particularly the problems arising from the construction and calibration of the cell. In the second part, a study of the interplanetary environment made from the D2A determinations is presented in synthesized form. On the other hand, the study to which theses initial results led us is presented in detail. Finally, in the third part, the results obtained by means of the OSO-8 and Copernicus satellites are given [fr

  6. Clustering of galaxies near damped Lyman-alpha systems with (z) = 2.6

    Science.gov (United States)

    Wolfe, A. M

    1993-01-01

    The galaxy two-point correlation function, xi, at (z) = 2.6 is determined by comparing the number of Ly-alpha-emitting galaxies in narrowband CCD fields selected for the presence of damped L-alpha absorption to their number in randomly selected control fields. Comparisons between the presented determination of (xi), a density-weighted volume average of xi, and model predictions for (xi) at large redshifts show that models in which the clustering pattern is fixed in proper coordinates are highly unlikely, while better agreement is obtained if the clustering pattern is fixed in comoving coordinates. Therefore, clustering of Ly-alpha-emitting galaxies around damped Ly-alpha systems at large redshifts is strong. It is concluded that the faint blue galaxies are drawn from a parent population different from normal galaxies, the presumed offspring of damped Ly-alpha systems.

  7. Effect of adrenaline and alpha-agonists on net rate of liquid absorption from the pleural space of rabbits.

    Science.gov (United States)

    Zocchi, L; Raffaini, A; Agostoni, E

    1997-05-01

    Indirect evidence supporting a solute-coupled liquid absorption from the pleural space of rabbits has recently been provided; moreover, the beta 2-adrenoceptor agonist terbutaline has been found to increase this absorption. In this study the effect of adrenaline and alpha-adrenoceptor agonists on net rate of liquid absorption (Jnet) from albumin Ringer hydrothoraces of various sizes has been determined in anaesthetized rabbits. In hydrothoraces with adrenaline (5 x 10(-6) M) the relationship between Jnet and volume of liquid injected was displaced upwards by 0.09 ml h-1 relative to that in control hydrothoraces (P liquid absorption, since beta-agonists inhibit lymphatic activity while, at relatively high concentrations, they may increase active transport. Conversely, the strong stimulation of lymphatic alpha-receptors that should occur with adrenaline after beta-blockade may fail to increase lymphatic drainage, because it has been shown that the increase in contraction frequency of lymphatics may be balanced by the decrease in their stroke volume. Arterial blood pressure during the hydrothoraces with adrenaline was unchanged. In hydrothoraces with the alpha 2-agonist clonidine (5 x 10(-6) M; a less potent agent than adrenaline) the slope of the relationship between Jnet and volume injected increased by 26% (P liquid load. In hydrothoraces with the alpha 1-agonist phenylephrine (5 x 10(-6) or 10(-7) M) Jnet was simlar to control values.

  8. Performance of Active Wave Absorption Systems

    DEFF Research Database (Denmark)

    Hald, Tue; Frigaard, Peter

    on a horisontal and vertical velocity are treated. All three systems are based on digital FIR-filters. For numerical comparison a performance function combining the frequency response of the set of filters for each system is derived enabling discussion on optimal filter design and system setup. Irregular wave......A comparison of wave gauge based on velocity meter based active absorption systems is presented discussing advantages and disadvantages of the systems. In detail one system based on two surface elevations, one system based on a surface elevation and a horisontal velocity and one system based...... tests with a highly reflective structure with the purely wave gauge based system and the wave gauge velocity meter based system are performed. The wave test depict the differences between the systems....

  9. Pharmacokinetics and Pharmacodynamics of Tamsulosin in its Modified-Release and Oral Controlled Absorption System Formulations

    NARCIS (Netherlands)

    Franco-Salinas, Gabriela; de La Rosette, Jean J. M. C. H.; Michel, Martin C.

    2010-01-01

    Tamsulosin is an alpha(1)-adrenoceptor antagonist used for the treatment of lower urinary tract symptoms that are suggestive of benign prostatic hyperplasia. It is mostly used in a modified-release (M R) Formulation. but an oral controlled absorption system (OCAS) and a 'without-water' tablet

  10. Calibration of sources for alpha spectroscopy systems

    International Nuclear Information System (INIS)

    Freitas, I.S.M.; Goncalez, O.L.

    1992-01-01

    This paper describes the calibration methodology for measuring the total alpha activity of plane and thin sources with the Alpha Spectrometer for Silicon Detector in the Nuclear Measures and Dosimetry laboratory at IEAv/CTA. (author)

  11. Acute moderate elevation of TNF-{alpha} does not affect systemic and skeletal muscle protein turnover in healthy humans

    DEFF Research Database (Denmark)

    Petersen, Anne Marie; Plomgaard, Peter; Fischer, Christian P

    2009-01-01

    -alpha infusion (rhTNF-alpha). We hypothesize that TNF-alpha increases human muscle protein breakdown and/or inhibit synthesis. Subjects and Methods: Using a randomized controlled, crossover design post-absorptive healthy young males (n=8) were studied 2 hours under basal conditions followed by 4 hours infusion...... with the phenylalanine 3-compartment model showed similar muscle synthesis, breakdown and net muscle degradation after 2 hours basal and after 4 hours Control or rhTNF-alpha infusion. Conclusion: This study is the first to show in humans that TNF-alpha does not affect systemic and skeletal muscle protein turnover, when......Context: Skeletal muscle wasting has been associated with elevations in circulating inflammatory cytokines, in particular TNF-alpha. Objective: In this study, we investigated whether TNF-alpha affects human systemic and skeletal muscle protein turnover, via a 4 hours recombinant human TNF...

  12. Endovascular vein harvest: systemic carbon dioxide absorption.

    Science.gov (United States)

    Maslow, Andrew M; Schwartz, Carl S; Bert, Arthur; Hurlburt, Peter; Gough, Jeffrey; Stearns, Gary; Singh, Arun K

    2006-06-01

    Endovascular vein harvest (EDVH) requires CO(2) insufflation to expand the subcutaneous space, allowing visualization and dissection of the saphenous vein. The purpose of this study was to assess the extent of CO(2) absorption during EDVH. Prospective observational study. Single tertiary care hospital. Sixty patients (30 EDVH and 30 open-vein harvest) undergoing isolated coronary artery bypass graft surgery. Hemodynamic, procedural, and laboratory data were collected prior to (baseline), during, and at it the conclusion (final) of vein harvesting. Data were also collected during cardiopulmonary bypass (CPB). Data were compared by using t tests, analysis of variance, and correlation statistics when needed. There were significant increases in arterial CO(2) (PaCO(2), 35%) and decreases in pH (1.35%) during EDVH. These were associated with increases in heart rate, mean blood pressure, and cardiac output. Within the EDVH group, greater elevations (>10 mmHg) in PaCO2 were more likely during difficult harvest procedures, and these patients exhibited greater increase in heart rate. Elevated CO(2) persisted during CPB, requiring higher systemic gas flows and greater use of phenylephrine to maintain desired hemodynamics. EDVH was associated with systemic absorption of CO(2). Greater absorption was more likely in difficult procedures and was associated with greater hemodynamic changes requiring medical therapy.

  13. Dynamical chaos in a linear 3. alpha. system. Dinamicheskij khaos v linejnoj 3. alpha. -sisteme

    Energy Technology Data Exchange (ETDEWEB)

    Bolotin, Yu L; Gonchar, V Yu; Chekanov, N A [AN Ukrainskoj SSR, Kharkov (Ukrainian SSR). Fiziko-Tekhnicheskij Inst.; Vinitskij, S I [Joint Inst. for Nuclear Research, Dubna (USSR)

    1989-01-01

    Classical dynamics of the motion of a molecular model of the carbon nucleus, which is a linear 3{alpha} system with realistic {alpha}{alpha} interaction is studied. Transition from a regular to a chaos motion in the nuclear molecule is shown to occur with growing energy more rapidly than in model problems with polynomial potentials. It is found that in a small region of the phase space the motion remains regular at energies higher than the 3{alpha}-system dissociation threshold. This is probably related to the C{sub 3v}-symmetry violation. Formulas for the quasiclassical spectrum of the 3{alpha} system are obtained with the use of the Birkhoff normal form.

  14. Absorption and transport of deuterium-substituted 2R,4'R,8'R-alpha-tocopherol in human lipoproteins

    International Nuclear Information System (INIS)

    Traber, M.G.; Ingold, K.U.; Burton, G.W.; Kayden, H.J.

    1988-01-01

    Oral administration of a single dose of tri- or hexadeuterium substituted 2R,4'R,8'R-alpha-tocopheryl acetate (d3- or d6-alpha-T-Ac) to humans was used to follow the absorption and transport of vitamin E in plasma lipoproteins. Three hr after oral administration of d3-alpha-T-Ac (15 mg) to 2 subjects, plasma levels of d3-alpha-T were detectable; these increased up to 10 hr, reached a plateau at 24 hr, then decreased. Following administration of d6-alpha-T-Ac (15-16 mg) to 2 subjects, the percentage of deuterated tocopherol relative to the total tocopherol in chylomicrons increased more rapidly than the corresponding percentage in whole plasma. Chylomicrons and plasma lipoproteins were isolated from 2 additional subjects following administration of d3-alpha-T-Ac (140 or 60 mg). The percentage of deuterated tocopherol relative to the total tocopherol increased most rapidly in chylomicrons, then in very low density lipoproteins (VLDL), followed by essentially identical increases in low and high density lipoproteins (LDL and HDL, respectively) and lastly, in the red blood cells. This pattern of appearance of deuterated tocopherol is consistent with the concept that newly absorbed vitamin E is secreted by the intestine into chylomicrons; subsequently, chylomicron remnants are taken up by the liver from which the vitamin E is secreted in VLDL. The metabolism of VLDL in the circulation results in the simultaneous delivery of vitamin E into LDL and HDL

  15. Determination of self absorption correction factor (SAF) for gross alpha measurement in water samples by BIS method

    International Nuclear Information System (INIS)

    Raveendran, Nanda; Baburajan, A.; Ravi, P.M.

    2018-01-01

    The laboratories accredited by AERB undertake the measurement of gross alpha and gross beta in packaged drinking water from manufactures across the country and analyze as per the procedure of Bureau of Indian standards. The accurate measurements of gross alpha in the drinking water sample is a challenge due to the self absorption of alpha particle from varying precipitate (Fe(OH) 3 +BaSO 4 ) thickness and total dissolved solids (TDS). This paper deals with a study on tracer recovery generation and self absorption correction factor (SAF). ESL, Tarapur has participated in an inter-laboratory comparison exercise conducted by IDS, RSSD, BARC as per the recommendation of AERB for the accredited laboratories. The thickness of the precipitate is an important aspect which affected the counting process. The activity was reported after conducting multiple experiments with uranium tracer recovery and precipitate thickness. Later on to make our efforts simplified, an average tracer recovery and Self Absorption correction Factor (SAF) was derived by the present experiment and the same was used for the re-calculation of activity from the count rate reported earlier

  16. Technical Equivalency Documentation for a Newly Acquired Alpha Spectroscopy System

    International Nuclear Information System (INIS)

    Hickman, D P; Fisher, S K; Hann, P R; Hume, R

    2007-01-01

    The response of a recently acquired Canberra(trademark) Alpha Analyst 'Blue' system (Chamber Number's 173-208) used by the Hazards Control, Radiation Safety Section, WBC/Spectroscopy Team has been studied with respect to an existing Canberra system. The existing Canberra system consists of thirty Alpha Analyst dual chambers Model XXXX comprising a total of sixty detectors (Chambers Number's 101-124 and 137-172). The existing chambers were previously compared to an older system consisting of thirty-six Model 7401 alpha spectrometry chambers (Chamber Number's 1-36) Chambers 101-124 and 137-172 are DOELAP accredited. The older system was previously DOELAP accredited for the routine Alpha Spectroscopy program used in LLNL's in vitro bioassay program. The newly acquired Alpha Analyst system operates on a network with software that controls and performs analysis of the current Alpha Analyst system (Chamber Number's 101-124 and 137-172). This exact same software is used for the current system and the newly acquired system and is DOELAP accredited. This document compares results from the existing Alpha System with the newer Alpha Analyst system

  17. Analysis of a solar powered absorption system

    International Nuclear Information System (INIS)

    Said, S.A.M.; El-Shaarawi, M.A.I.; Siddiqui, M.U.

    2015-01-01

    Highlights: • Conventional absorption system modified to increase COP. • Results indicated increase of 10% in COP due to dephlegmator heat recovery. • Results indicated increase of 8% in COP due to refrigerant storage unit. • Results indicated increase of 18% in COP due to combined effect of modifications. • Simulation results indicated a very good agreement with the measured results. - Abstract: Today, fossil fuel is the primary extensively used source of energy. However, its negative impact on the environment have forced the energy research continuity to seriously consider renewable sources of energy. Solar energy, in particular, has been the main focus in this regard because it is a source of clean energy and naturally available. This study presents the design and analysis of a solar powered absorption refrigeration system modified to increase its coefficient of performance (COP). The modifications include recovering of waste heat from a dephlegmator and utilization of a refrigerant storage unit. The simulation results indicate an increase of 10% in the COP of the conventional design using dephlegmator heat recovery and an increase of 8% in the COP of the conventional design due to the use of a refrigerant storage. The analysis for the combined effect of modifications indicates an increase of 18% in the COP compared to conventional design. Calculated values of coefficient of performance indicate a very good agreement with the ones obtained based on measurement

  18. Increased virulence and competitive advantage of a/alpha over a/a or alpha/alpha offspring conserves the mating system of Candida albicans.

    Science.gov (United States)

    Lockhart, Shawn R; Wu, Wei; Radke, Joshua B; Zhao, Rui; Soll, David R

    2005-04-01

    The majority of Candida albicans strains in nature are a/alpha and must undergo homozygosis to a/a or alpha/alpha to mate. Here we have used a mouse model for systemic infection to test the hypothesis that a/alpha strains predominate in nature because they have a competitive advantage over a/a and alpha/alpha offspring in colonizing hosts. Single-strain injection experiments revealed that a/alpha strains were far more virulent than either their a/a or alpha/alpha offspring. When equal numbers of parent a/alpha and offspring a/a or alpha/alpha cells were co-injected, a/alpha always exhibited a competitive advantage at the time of extreme host morbidity or death. When equal numbers of an engineered a/a/alpha2 strain and its isogenic a/a parent strain were co-injected, the a/a/alpha2 strain exhibited a competitive advantage at the time of host morbidity or death, suggesting that the genotype of the mating-type (MTL) locus, not associated genes on chromosome 5, provides a competitive advantage. We therefore propose that heterozygosity at the MTL locus not only represses white-opaque switching and genes involved in the mating process, but also affects virulence, providing a competitive advantage to the a/alpha genotype that conserves the mating system of C. albicans in nature.

  19. Set-up of an alpha-spectrometry system

    International Nuclear Information System (INIS)

    Calicchia, A.

    1976-01-01

    Principle of operation of alpha-spectrometry system is described, using a solid state detector, which allows to precisely determine sample's activity and specify alpha-emitting radionuclides. Measurements which allow to define system performances are shown, that is energy resolution and real sensitivity of spectrometer

  20. alpha-MSH in systemic inflammation. Central and peripheral actions.

    Science.gov (United States)

    Catania, A; Delgado, R; Airaghi, L; Cutuli, M; Garofalo, L; Carlin, A; Demitri, M T; Lipton, J M

    1999-10-20

    Until recently, inflammation was believed to arise from events taking place exclusively in the periphery. However, it is now clear that central neurogenic influences can either enhance or modulate peripheral inflammation. Therefore, it should be possible to improve treatment of inflammation by use of antiinflammatory agents that reduce peripheral host responses and inhibit proinflammatory signals in the central nervous system (CNS). One such strategy could be based on alpha-melanocyte stimulating hormone (alpha-MSH). Increases in circulating TNF-alpha and nitric oxide (NO), induced by intraperitoneal administration of endotoxin in mice, were modulated by central injection of a small concentration of alpha-MSH. Inducible nitric oxide synthase (iNOS) activity and iNOS mRNA in lungs and liver were likewise modulated by central alpha-MSH. Increase in lung myeloperoxidase (MPO) activity was significantly less in lungs of mice treated with central alpha-MSH. Proinflammatory agents induced by endotoxin were significantly greater after blockade of central alpha-MSH. The results suggest that antiinflammatory influences of neural origin that are triggered by alpha-MSH could be used to treat systemic inflammation. In addition to its central influences, alpha-MSH has inhibitory effects on peripheral host cells, in which it reduces release of proinflammatory mediators. alpha-MSH reduces chemotaxis of human neutrophils and production of TNF-alpha, neopterin, and NO by monocytes. In research on septic patients, alpha-MSH inhibited release of TNF-alpha, interleukin-1 beta (IL-1 beta), and interleukin-8 (IL-8) in whole blood samples in vitro. Combined central and peripheral influences can be beneficial in treatment of sepsis.

  1. Ultraviolet photometry from the orbiting astronomical observatory. XVI - The stellar Lyman-alpha absorption line

    Science.gov (United States)

    Savage, B. D.; Panek, R. J.

    1974-01-01

    The stellar Lyman-alpha line at 1216 A was observed in 29 lightly reddened stars of spectral type B2.5 to B9 by a far-UV spectrophotometer on OAO-2. The equivalent widths obtained range from 15 A at type B2.5 to 65 A at type B8; in the late-B stars, the L-alpha line removes 2 to 3% of the total stellar flux. In this sampling, the strength of the L-alpha line correlates well with measures of the Balmer discontinuity and Balmer line strengths; luminosity classification does not seem to affect the line strength. The observed line widths also agree with the predictions of Mihala's grid of non-LTE model atmospheres. In some cases, the L-alpha line influences the interstellar column densities reported in the interstellar OAO-2 L-alpha survey. Hence, these data toward lightly reddened B2 and B1.5 stars should be regarded as upper limits only.

  2. Self-absorption and self-scattering in emitter source of alpha particles

    International Nuclear Information System (INIS)

    Terini, R.A.

    1990-01-01

    This paper describes preliminary results on spectrometric analysis and activity measurements of alpha-emitting sources prepared by evaporation on mylar. The measurements were made with a Si surface barrier detector. By the analysis of the angular distribuition of the alpha particles emitted, it was possible to observe that the width of the spectrum low energy tail increases with the emission angle θ, due to the energy degradation in the source material, which affects the measured particles energy. The source activity was also measured from detection solid angles of approx. 10 -1 and aprox. 10 -3 Sr, as a function of θ. The absolute activity of the alpha source was determined and a discussion is present on the ideal conditions necessary for such measurements. (author) [pt

  3. Gintonin absorption in intestinal model systems

    Directory of Open Access Journals (Sweden)

    Byung-Hwan Lee

    2018-01-01

    Conclusion: The present study shows that gintonin could be absorbed in the intestine through transcellular and paracellular diffusion, and active transport. In addition, the lipid component of gintonin might play a key role in its intestinal absorption.

  4. Simulation of absorption refrigeration system for automobile application

    Directory of Open Access Journals (Sweden)

    Ramanathan Anand

    2008-01-01

    Full Text Available An automotive air-conditioning system based on absorption refrigeration cycle has been simulated. This waste heat driven vapor absorption refrigeration system is one alternate to the currently used vapour compression refrigeration system for automotive air-conditioning. Performance analysis of vapor absorption refrigeration system has been done by developing a steady-state simulation model to find the limitation of the proposed system. The water-lithium bromide pair is used as a working mixture for its favorable thermodynamic and transport properties compared to the conventional refrigerants utilized in vapor compression refrigeration applications. The pump power required for the proposed vapor absorption refrigeration system was found lesser than the power required to operate the compressor used in the conventional vapor compression refrigeration system. A possible arrangement of the absorption system for automobile application is proposed.

  5. Radon compensation for alpha air monitoring systems

    International Nuclear Information System (INIS)

    Fleming, D.M.; Rising, F.L.; Zuerner, L.V.

    1975-01-01

    Continuous alpha air monitors, employing solid state detectors and single channel analyzers, for the detection of alpha particles of a specific energy have been available commercially for several years. The single channel pulse height analyzers provide good sensitivity to the isotope of interest and reject much of the unwanted activity from other isotopes such as naturally occurring radon and daughters. A small percentage of the radon daughters are degraded in energy by the air between the collecting filter and the diode to the extent that they coincide with energy of the isotope being measured and are counted as unwanted background. When 239 Pu is the isotope being measured the activity in the Pu channel resulting from radon is typically 2 percent of the total radon background. The majority of this unwanted background results from the degradation of the 6.0 MeV 218 Po (RaA) peak. This background is sufficient to cause instrument alarms during periods of radon activity. In attempts to reduce the frequency of false alarms, background subtraction circuits have been added as standard equipment to most of the alpha air monitors available on the market for the past several years. A method for calibrating these background subtraction circuits using a radon generator is described. (U.S.)

  6. Cloud Absorption Radiometer Autonomous Navigation System - CANS

    Science.gov (United States)

    Kahle, Duncan; Gatebe, Charles; McCune, Bill; Hellwig, Dustan

    2013-01-01

    CAR (cloud absorption radiometer) acquires spatial reference data from host aircraft navigation systems. This poses various problems during CAR data reduction, including navigation data format, accuracy of position data, accuracy of airframe inertial data, and navigation data rate. Incorporating its own navigation system, which included GPS (Global Positioning System), roll axis inertia and rates, and three axis acceleration, CANS expedites data reduction and increases the accuracy of the CAR end data product. CANS provides a self-contained navigation system for the CAR, using inertial reference and GPS positional information. The intent of the software application was to correct the sensor with respect to aircraft roll in real time based upon inputs from a precision navigation sensor. In addition, the navigation information (including GPS position), attitude data, and sensor position details are all streamed to a remote system for recording and later analysis. CANS comprises a commercially available inertial navigation system with integral GPS capability (Attitude Heading Reference System AHRS) integrated into the CAR support structure and data system. The unit is attached to the bottom of the tripod support structure. The related GPS antenna is located on the P-3 radome immediately above the CAR. The AHRS unit provides a RS-232 data stream containing global position and inertial attitude and velocity data to the CAR, which is recorded concurrently with the CAR data. This independence from aircraft navigation input provides for position and inertial state data that accounts for very small changes in aircraft attitude and position, sensed at the CAR location as opposed to aircraft state sensors typically installed close to the aircraft center of gravity. More accurate positional data enables quicker CAR data reduction with better resolution. The CANS software operates in two modes: initialization/calibration and operational. In the initialization/calibration mode

  7. Comparison of the cardiovascular effects of tamsulosin oral controlled absorption system (OCAS) and alfuzosin prolonged release (XL)

    NARCIS (Netherlands)

    Michel, Martin C.; Chapple, Christopher R.

    2006-01-01

    OBJECTIVE: The cardiovascular (CV) effects of tamsulosin oral controlled absorption system (OCAS) 0.4 mg were compared with those of alfuzosin prolonged release (XL) 10 mg. METHODS: Two single-dose, crossover studies were performed. In study 1, CV alpha1-adrenoceptor antagonism was assessed by

  8. Alpha low-level stored waste systems design study

    Energy Technology Data Exchange (ETDEWEB)

    Feizollahi, F.; Teheranian, B. (Morrison Knudson Corp., San Francisco, CA (United States). Environmental Services Div.); Quapp, W.J. (EG and G Idaho, Inc., Idaho Falls, ID (United States))

    1992-08-01

    The Stored Waste System Design Study (SWSDS), commissioned by the Waste Technology Development Department at the Idaho National Engineering Laboratory (INEL), examines relative life-cycle costs associated with three system concepts for processing the alpha low-level waste (alpha-LLW) stored at the Radioactive Waste Management Complex's Transuranic Storage Area at the INEL. The three system concepts are incineration/melting; thermal treatment/solidification; and sort, treat, and repackage. The SWSDS identifies system functional and operational requirements and assesses implementability; effectiveness; cost; and demonstration, testing, and evaluation (DT E) requirements for each of the three concepts.

  9. Alpha low-level stored waste systems design study

    Energy Technology Data Exchange (ETDEWEB)

    Feizollahi, F.; Teheranian, B. [Morrison Knudson Corp., San Francisco, CA (United States). Environmental Services Div.; Quapp, W.J. [EG and G Idaho, Inc., Idaho Falls, ID (United States)

    1992-08-01

    The Stored Waste System Design Study (SWSDS), commissioned by the Waste Technology Development Department at the Idaho National Engineering Laboratory (INEL), examines relative life-cycle costs associated with three system concepts for processing the alpha low-level waste (alpha-LLW) stored at the Radioactive Waste Management Complex`s Transuranic Storage Area at the INEL. The three system concepts are incineration/melting; thermal treatment/solidification; and sort, treat, and repackage. The SWSDS identifies system functional and operational requirements and assesses implementability; effectiveness; cost; and demonstration, testing, and evaluation (DT&E) requirements for each of the three concepts.

  10. Alpha low-level stored waste systems design study

    International Nuclear Information System (INIS)

    Feizollahi, F.; Teheranian, B.

    1992-08-01

    The Stored Waste System Design Study (SWSDS), commissioned by the Waste Technology Development Department at the Idaho National Engineering Laboratory (INEL), examines relative life-cycle costs associated with three system concepts for processing the alpha low-level waste (alpha-LLW) stored at the Radioactive Waste Management Complex's Transuranic Storage Area at the INEL. The three system concepts are incineration/melting; thermal treatment/solidification; and sort, treat, and repackage. The SWSDS identifies system functional and operational requirements and assesses implementability; effectiveness; cost; and demonstration, testing, and evaluation (DT ampersand E) requirements for each of the three concepts

  11. Model systems for understanding absorption tuning by opsin proteins

    DEFF Research Database (Denmark)

    Nielsen, Mogens Brøndsted

    2009-01-01

    This tutorial review reports on model systems that have been synthesised and investigated for elucidating how opsin proteins tune the absorption of the protonated retinal Schiff base chromophore. In particular, the importance of the counteranion is highlighted. In addition, the review advocates...... is avoided, and it becomes clear that opsin proteins induce blueshifts in the chromophore absorption rather than redshifts....

  12. The Role of Absorption Cooling for Reaching Sustainable Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    Lindmark, Susanne

    2005-07-01

    This thesis focuses on the role and potential of absorption cooling in future energy systems. Two types of energy systems are investigated: a district energy system based on waste incineration and a distributed energy system with natural gas as fuel. In both cases, low temperature waste heat is used as driving energy for the absorption cooling. The main focus is to evaluate the absorption technology in an environmental perspective, in terms of reduced CO{sub 2} emissions. Economic evaluations are also performed. The reduced electricity when using absorption cooling instead of compression cooling is quantified and expressed as an increased net electrical yield. The results show that absorption cooling is an environmentally friendly way to produce cooling as it reduces the use of electrically driven cooling in the energy system and therefore also reduces global CO{sub 2} emissions. In the small-scale trigeneration system the electricity use is lowered with 84 % as compared to cooling production with compression chillers only. The CO{sub 2} emissions can be lowered to 45 CO{sub 2}/MWh{sub c} by using recoverable waste heat as driving heat for absorption chillers. However, the most cost effective cooling solution in a district energy system is a combination between absorption and compression cooling technologies according to the study. Absorption chillers have the potential to be suitable bottoming cycles for power production in distributed systems. Net electrical yields over 55 % may be reached in some cases with gas motors and absorption chillers. This small-scale system for cogeneration of power and cooling shows electrical efficiencies comparable to large-scale power plants and may contribute to reducing peak electricity demand associated with the cooling demand.

  13. The low-ion QSO absorption-line systems

    International Nuclear Information System (INIS)

    Lanzetta, K.M.

    1988-01-01

    Various techniques are used to investigate the class of QSO absorption-line systems that exhibit low-ion absorption lines. Four separate investigations are conducted as follows: Spectroscopy of 32 QSOs at red wavelengths is presented and used to investigate intermediate-redshift MgII absorption. A total of 22 Mg II doublets are detected, from which properties of the Mg II absorbers are derived. Marginal evidence for intrinsic evolution of the number density of the Mg II absorbers with redshift is found. The data are combined with previous observations of C IV and C II seen in the same QSOs at blue wavelengths, and the properties of Mg II- and C IV-selected systems are compared. A sample is constructed of 129 QSOs for which are available published data suitable for detecting absorption-line systems that are optically thick to Lyman continuum radiation. A total of 53 such Lyman-limit systems are found, from which properties of the Lyman-limit systems are derived. It is found that the rate of incidence of the systems does not strongly evolved with redshift. This result is contrasted with the evolution found previously for systems selected on the basis of Mg II absorption. Spectroscopy at red wavelengths of eight QSOs with known damped Lyα absorption systems is presented. Spectroscopic and spectrophotometric observations aimed at detecting molecular hydrogen and dust in the z = 2.796 damped Lyα absorber toward Q1337 + 113 are presented

  14. Alpha Channeling in Open-System Magnetic Devices

    International Nuclear Information System (INIS)

    Fisch, Nathaniel

    2016-01-01

    The Grant DE-SC0000736, Alpha Channeling in Open-System Magnetic Devices, is a continuation of the Grant DE-FG02-06ER54851, Alpha Channeling in Mirror Machines. In publications funded by DE-SC0000736, the grant DE-FG02-06ER54851 was actually credited. The key results obtained under Grant DE-SC0000736, Alpha Channeling in Open-System Magnetic Devices, appear in a series of publications. The earlier effort under DE-FG02- 06ER54851 was the subject of a previous Final Report. The theme of this later effort has been unusual confinement effects, or de-confinement effects, in open-field magnetic confinement devices. First, the possibilities in losing axisymmetry were explored. Then a number of issues in rotating plasma were addressed. Most importantly, a spinoff application to plasma separations was recognized, which also resulted in a provisional patent application. (That provisional patent application, however, was not pursued further.) Alpha channeling entails injecting waves into magnetically confined plasma to release energy from one particular ion while ejecting that ion. The ejection of the ion is actually a concomitant effect in releasing energy from the ion to the wave. In rotating plasma, there is the opportunity to store the energy in a radial electric field rather than in waves. In other words, the ejected alpha particle loses its energy to the radial potential, which in turn produces plasma rotation. This is a very useful effect, since producing radial electric fields by other means are technologically more difficult. In fact, one can heat ions, and then eject them, to produce the desired radial field. In each case, there is a separation effect of different ions, which generalizes the original alpha-channeling concept of separating alpha ash from hydrogen. In a further generalization of the separation concept, a double-well filter represents a new way to produce high-throughput separations of ions, potentially useful for nuclear waste remediation.

  15. Oasis-an innovative system for alpha spectroscopy

    International Nuclear Information System (INIS)

    Seymour, R.; Richards, W.; Knight, K.; El-Sayad, G.

    1995-01-01

    Until recently, instrumental alpha spectroscopy has behind the technical developments of instrumentation and software that are available for low background o c/ counting, liquid scintillation, and gamma spectroscopy instruments. We report in this paper, the development of Oasis, a new family of alpha spectroscopy systems from oxford instruments Inc., Nuclear measurements Group. The Oasis instruments incorporate many hardware and software innovations providing an automated and integrated production environment for alpha spectroscopy. These instruments are needed because of the large number of samples to be measured and the required throughput of production laboratories processing these samples. Oasis is also useful for facilities because of their sophisticated vacuum control, management, and analysis features. One of the most important innovations is the electronic vacuum system and cartesian diver. Many additional features contribute to improving accuracy, lowering cost per sample, improving sample throughput, and ensuring accountability of laboratory results. 5 figs

  16. Oasis-an innovative system for alpha spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Seymour, R; Richards, W; Knight, K; El-Sayad, G [Oxford Instruments Inc., P.O. Box 2560, Oak Ridge, TN 37831-2560 (United States)

    1995-10-01

    Until recently, instrumental alpha spectroscopy has behind the technical developments of instrumentation and software that are available for low background o c/ counting, liquid scintillation, and gamma spectroscopy instruments. We report in this paper, the development of Oasis, a new family of alpha spectroscopy systems from oxford instruments Inc., Nuclear measurements Group. The Oasis instruments incorporate many hardware and software innovations providing an automated and integrated production environment for alpha spectroscopy. These instruments are needed because of the large number of samples to be measured and the required throughput of production laboratories processing these samples. Oasis is also useful for facilities because of their sophisticated vacuum control, management, and analysis features. One of the most important innovations is the electronic vacuum system and cartesian diver. Many additional features contribute to improving accuracy, lowering cost per sample, improving sample throughput, and ensuring accountability of laboratory results. 5 figs.

  17. Artificial neural network analysis of triple effect absorption refrigeration systems

    Energy Technology Data Exchange (ETDEWEB)

    Hajizadeh Aghdam, A. [Department of Mechanical Engineering, Islamic Azad University (Iran, Islamic Republic of)], email: a.hajizadeh@iaukashan.ac.ir; Nazmara, H.; Farzaneh, B. [Department of Mechanical Engineering, University of Tabriz (Iran, Islamic Republic of)], email: h.nazmara@nioec.org, email: b_farzaneh_ms@yahoo.com

    2011-07-01

    In this study, artificial neural networks are utilized to predict the performance of triple effect series and parallel flow absorption refrigeration systems, with lithium bromide/water as the working fluid. Important parameters such as high generator and evaporator temperatures were varied and their effects on the performance characteristics of the refrigeration unit were observed. Absorption refrigeration systems make energy savings possible because they can use heat energy to produce cooling, in place of the electricity used for conventional vapour compression chillers. In addition, non-conventional sources of energy (such as solar, waste heat, and geothermal) can be utilized as their primary energy input. Moreover, absorption units use environmentally friendly working fluid pairs instead of CFCs and HCFCs, which affect the ozone layer. Triple effect absorption cycles were analysed. Results apply for both series and parallel flow systems. A relative preference for parallel-flow over series-flow is also shown.

  18. Observations of nickel, chromium, and zinc in QSO absorption-line systems

    International Nuclear Information System (INIS)

    Meyer, D.M.; Roth, K.C.

    1990-01-01

    New observations of Ni II, Cr II, and Zn II in several damped Ly-alpha QSO absorption-line systems at z about 2 are presented. Using the N(Zn II)/N(H I) ratio as a probe of the metallicity and N(Cr II)/N(Zn II) as a measure of the dust content, it is found that the heavy-element abundances in the z = 1.921 system toward the QSO 2206-199N are 20 percent solar and that the dust-to-gas ratio is 11 percent of the Galactic disk value. The observations of these species in the z = 2.309 system toward PHL 957 yield a more extreme metallicity (4 percent solar) and dust-to-gas ratio (3 percent Galactic). In addition, a depletion of Ni in the z = 2.039 absorber toward PKS 0458 - 020 and an absence of C I absorption in the z about 2 damped systems toward 1215 + 333 and 2359 - 022 are found which are consistent with a lack of dust. Among the four damped systems whose Ni, Cr, and Zn abundances have been examined quantitatively to date, all show convincing evidence of much lower metallicities and dust content than the Galactic disk. The implications of these results with regard to the interpretation of the high-redshift damped Ly-alpha systems as an evolving population of young galaxies are discussed. 41 refs

  19. The distribution of absorptive power dissipation in irradiated nanoparticulate system

    International Nuclear Information System (INIS)

    Li, Jiayu; Yang, Jian; Gu, Xiaobing

    2016-01-01

    The knowledge of local radiant absorption is important to the nanostructure optimization, it is beneficial to the applications in energy harvesting, optical heating, photocatalysis, etc. In this paper, FDTD model is constructed for the distribution of absorptive power dissipation in irradiated nanoparticulate system. The theoretical model extended from Mie theory is used to examine the FDTD model, the parameters and conditions set for FDTD simulation are confirmed based on the comparison. Then, the influence of Ag nanoparticle on the absorptive properties of nearby TiO_2 nanoparticle is investigated by FDTD simulation at the wavelength of 0.25 μm. It is indicated that suitable distance between TiO_2 and Ag particles is beneficial to the spectral radiant absorption of TiO_2 particle. Considering the agglomeration of nanoparticles and the oxidation at the TiO_2–Ag interface, the Ag core coated with Al_2O_3 shell is suggested, and the simulated results indicated that the shell thickness and the Ag core size need to be optimized for enhancing the radiant absorption of TiO_2 particle. - Highlights: • The absorptive power distribution in nanoparticulate system is simulated by FDTD. • FDTD simulation is compared with theoretical model extended from Mie theory. • The parameters and conditions are confirmed based on the comparison. • The influence of Ag nanoparticle on nearby TiO_2 particle's absorption is analyzed.

  20. Deficiency of a alpha-1-antitrypsin influences systemic iron homeostasis

    Science.gov (United States)

    Abstract Background: There is evidence that proteases and anti-proteases participate in the iron homeostasis of cells and living systems. We tested the postulate that alpha-1 antitrypsin (A1AT) polymorphism and the consequent deficiency of this anti-protease in humans are asso...

  1. Portable wireless neurofeedback system of EEG alpha rhythm enhances memory.

    Science.gov (United States)

    Wei, Ting-Ying; Chang, Da-Wei; Liu, You-De; Liu, Chen-Wei; Young, Chung-Ping; Liang, Sheng-Fu; Shaw, Fu-Zen

    2017-11-13

    Effect of neurofeedback training (NFT) on enhancement of cognitive function or amelioration of clinical symptoms is inconclusive. The trainability of brain rhythm using a neurofeedback system is uncertainty because various experimental designs are used in previous studies. The current study aimed to develop a portable wireless NFT system for alpha rhythm and to validate effect of the NFT system on memory with a sham-controlled group. The proposed system contained an EEG signal analysis device and a smartphone with wireless Bluetooth low-energy technology. Instantaneous 1-s EEG power and contiguous 5-min EEG power throughout the training were developed as feedback information. The training performance and its progression were kept to boost usability of our device. Participants were blinded and randomly assigned into either the control group receiving random 4-Hz power or Alpha group receiving 8-12-Hz power. Working memory and episodic memory were assessed by the backward digital span task and word-pair task, respectively. The portable neurofeedback system had advantages of a tiny size and long-term recording and demonstrated trainability of alpha rhythm in terms of significant increase of power and duration of 8-12 Hz. Moreover, accuracies of the backward digital span task and word-pair task showed significant enhancement in the Alpha group after training compared to the control group. Our tiny portable device demonstrated success trainability of alpha rhythm and enhanced two kinds of memories. The present study suggest that the portable neurofeedback system provides an alternative intervention for memory enhancement.

  2. Spectrophotometer-Integrating-Sphere System for Computing Solar Absorptance

    Science.gov (United States)

    Witte, William G., Jr.; Slemp, Wayne S.; Perry, John E., Jr.

    1991-01-01

    A commercially available ultraviolet, visible, near-infrared spectrophotometer was modified to utilize an 8-inch-diameter modified Edwards-type integrated sphere. Software was written so that the reflectance spectra could be used to obtain solar absorptance values of 1-inch-diameter specimens. A descriptions of the system, spectral reflectance, and software for calculation of solar absorptance from reflectance data are presented.

  3. Second law analysis of double effect vapour absorption cooler system

    International Nuclear Information System (INIS)

    Gomri, Rabah; Hakimi, Riad

    2008-01-01

    In this paper, exergy analysis of double effect lithium bromide/water absorption refrigeration system is presented. The system consists of a second effect generator between the generator and condenser of the single effect absorption refrigeration system, including two solution heat exchangers between the absorber and the two generators. In order to simulate the refrigeration system by using a computer, a new set of computationally efficient formulations of thermodynamic properties of lithium bromide/water solution developed is used. The exergy analysis is carried out for each component of the system. All exergy losses that exist in double effect lithium bromide/water absorption system are calculated. In addition to the coefficient of performance and the exergetic efficiency of the system, the number of exergy of each component of the system is also estimated. This study suggests the component of the absorption refrigeration system that should be developed. The results show that the performance of the system increases with increasing low pressure generator (LPG) temperature, but decreases with increasing high pressure generator (HPG) temperature. The highest exergy loss occurs in the absorber and in the HPG, which therefore makes the absorber and HPG the most important components of the double effect refrigeration system

  4. Planet Detectability in the Alpha Centauri System

    Science.gov (United States)

    Zhao, Lily; Fischer, Debra A.; Brewer, John; Giguere, Matt; Rojas-Ayala, Bárbara

    2018-01-01

    We use more than a decade of radial-velocity measurements for α {Cen} A, B, and Proxima Centauri from the High Accuracy Radial Velocity Planet Searcher, CTIO High Resolution Spectrograph, and the Ultraviolet and Visual Echelle Spectrograph to identify the M\\sin i and orbital periods of planets that could have been detected if they existed. At each point in a mass–period grid, we sample a simulated, Keplerian signal with the precision and cadence of existing data and assess the probability that the signal could have been produced by noise alone. Existing data places detection thresholds in the classically defined habitable zones at about M\\sin i of 53 {M}\\oplus for α {Cen} A, 8.4 {M}\\oplus for α {Cen} B, and 0.47 {M}\\oplus for Proxima Centauri. Additionally, we examine the impact of systematic errors, or “red noise” in the data. A comparison of white- and red-noise simulations highlights quasi-periodic variability in the radial velocities that may be caused by systematic errors, photospheric velocity signals, or planetary signals. For example, the red-noise simulations show a peak above white-noise simulations at the period of Proxima Centauri b. We also carry out a spectroscopic analysis of the chemical composition of the α {Centauri} stars. The stars have super-solar metallicity with ratios of C/O and Mg/Si that are similar to the Sun, suggesting that any small planets in the α {Cen} system may be compositionally similar to our terrestrial planets. Although the small projected separation of α {Cen} A and B currently hampers extreme-precision radial-velocity measurements, the angular separation is now increasing. By 2019, α {Cen} A and B will be ideal targets for renewed Doppler planet surveys.

  5. PC based alpha, beta and gamma counting system

    International Nuclear Information System (INIS)

    Bhattacharya, S.; Gopalakrishnan, K.R.; Bairi, B.R.

    1992-01-01

    In the field of radiation protection and safety a large number of samples have to be assayed for estimation of their radioactivity at various stages in nuclear fuel. A PC based alpha, beta and gamma counting system has been designed for the above application. The system is fully automatic and requires minimum of operator intervention. The main units in the system are detector and pulse processing electronics, sample changer and assembly and IBM PC interface and supporting software. The main function of interface is to control the sample changer which is basically loading and unloading of sample, data acquisition and further processing by software. The pulses from detector are analysed in a pulse shape discriminator. A pulse identified as an alpha, beta or gamma event is converted to digital pulse. These digital pulses are accumulated in the three channels on PC interface each corresponding to alpha, beta and gamma. The sample movements are controlled by interface depending upon sample position. The software has been developed so as to maintain user friendliness and convenience of the operator. Various selection modes for parameters and operation of system provide lot of flexibility in operation of the system. (author). 1 fig

  6. Cosmological implications of the redshift distribution of QSO absorption systems

    International Nuclear Information System (INIS)

    Khare-Joshi, P.; Perry, J.J.

    1982-01-01

    We have used the observational data on QSO absorption redshifts, as compiled by Perry, Burbidge and Burbidge (1978) (hereafter PB 2 ), Drew (1978) and Weyman et al. (1979) (hereafter W 2 PT), to study various selection effects likely to affect the distribution of absorption redshifts and, then to determine the probable number distribution of absorbers per redshift interval of 0.1, as a function of z. The distribution obtained, assuming all the observed absorption to be intervening, is found to be statistically incompatible with the redshift distribution of galaxies with constant cross-section for any Friedman cosmology with zero cosmological constant and q 0 >= 0. Therefore, in order to eliminate the absorption systems which are plausibly intrinsic, we have applied the criterion suggested by W 2 PT and by the analysis of the distribution of absorption systems as a function of the relative velocity between the emitting and the absorbing gas, for the PB 2 data set; to wit, we have analysed the distributions obtained by assuming that those systems with relative velocity greater than 0.02 c, 0.02 c but not equal to 0.1 c to 0.11 c and 0.06 c respectively, or those systems without O VI and N V lines, are produced by the intervening galaxies. The results are discussed. (author)

  7. Optomechanically induced absorption in parity-time-symmetric optomechanical systems

    Science.gov (United States)

    Zhang, X. Y.; Guo, Y. Q.; Pei, P.; Yi, X. X.

    2017-06-01

    We explore the optomechanically induced absorption (OMIA) in a parity-time- (PT -) symmetric optomechanical system (OMS). By numerically calculating the Lyapunov exponents, we find out the stability border of the PT -symmetric OMS. The results show that in the PT -symmetric phase the system can be either stable or unstable depending on the coupling constant and the decay rate. In the PT -symmetric broken phase the system can have a stable state only for small gain rates. By calculating the transmission rate of the probe field, we find that there is an inverted optomechanically induced transparency (OMIT) at δ =-ωM and an OMIA at δ =ωM for the PT -symmetric optomechanical system. At each side of δ =-ωM there is an absorption window due to the resonance absorption of the two generated supermodes. Comparing with the case of optomechanics coupled to a passive cavity, we find that the active cavity can enhance the resonance absorption. The absorption rate at δ =ωM increases as the coupling strength between the two cavities increases. Our work provides us with a promising platform for controlling light propagation and light manipulation in terms of PT symmetry, which might have potential applications in quantum information processing and quantum optical devices.

  8. Multiple wavelength multitimescale optical absorption system

    International Nuclear Information System (INIS)

    Lubis, R.; Allan, D.; Hodgson, B.W.; Swallow, A.J.

    1992-01-01

    A new workstation for pulse radiolysis studies has been developed for the Paterson Institute Linear Accelerator Laboratory. It is particularly suited to the study of materials available only in limited quantities. The analysing light beam is dispersed into a plane spectrum by a McPherson 270 monochromator and focused down to a line spectrum by a rod lens. The spectral intensity distribution is sampled by a linear array of optical fibres which conduct the light to photodiodes. A preamplifier unit amplifies and buffers the diode photocurrent signal which then passes to the main electronics unit incorporating further amplification stages, filters, backing-off of the background photocurrent, analog-to-digital conversion, data storage memory and a computer interface. All control of the electronic system is performed from a computer equipped with appropriate software. The system has 10 channels of spectral bandwidth 16 nm, a useful spectral response from 350 nm to 1 μm with a high signal-to-noise ratio, signal sampling rates from 20 MHz to 2 kHz and 8 kbyte of local memory for each channel. (author)

  9. Multiple wavelength multitimescale optical absorption system

    Science.gov (United States)

    Lubis, R.; Allan, D.; Hodgson, B. W.; Swallow, A. J.

    A new workstation for pulse radiolysis studies has been developed for the Paterson Institute Linear Accelerator Laboratory. It is particularly suited to the study of materials available only in limited quantities. The analysing light beam is dispersed into a plane spectrum by a McPherson 270 monochromator and focused down to a line spectrum by a rod lens. The spectral intensity distribution is sampled by a linear array of optical fibres which conduct the light to photodiodes. A preamplifier unit amplifies and buffers the diode photocurrent signal which then passes to the main electronics unit incorporating further amplification stages, filters, backing-off of the background photocurrent, analog-to-digital conversion, data storage memory and a computer interface. All control of the electronic system is performed from a computer equipped with appropriate software. The system has 10 channels of spectral bandwidth 16 nm, a useful spectral response from 350 nm to 1 μm with a high signal-to-noise ratio, signal sampling rates from 20 MHz to 2 kHz and 8 kbyte of local memory for each channel.

  10. Computational Model of a Biomass Driven Absorption Refrigeration System

    Directory of Open Access Journals (Sweden)

    Munyeowaji Mbikan

    2017-02-01

    Full Text Available The impact of vapour compression refrigeration is the main push for scientists to find an alternative sustainable technology. Vapour absorption is an ideal technology which makes use of waste heat or renewable heat, such as biomass, to drive absorption chillers from medium to large applications. In this paper, the aim was to investigate the feasibility of a biomass driven aqua-ammonia absorption system. An estimation of the solid biomass fuel quantity required to provide heat for the operation of a vapour absorption refrigeration cycle (VARC is presented; the quantity of biomass required depends on the fuel density and the efficiency of the combustion and heat transfer systems. A single-stage aqua-ammonia refrigeration system analysis routine was developed to evaluate the system performance and ascertain the rate of energy transfer required to operate the system, and hence, the biomass quantity needed. In conclusion, this study demonstrated the results of the performance of a computational model of an aqua-ammonia system under a range of parameters. The model showed good agreement with published experimental data.

  11. Enhancing effect of medium-chain triglycerides on intestinal absorption of d-alpha-tocopherol acetate from lecithin-dispersed preparations in the rat.

    Science.gov (United States)

    Fukui, E; Kurohara, H; Kageyu, A; Kurosaki, Y; Nakayama, T; Kimura, T

    1989-02-01

    The effect of formulations of lecithin-dispersed preparation on the absorption of d-alpha-tocopherol acetate (VEA) from the small intestine was investigated in rats. When lecithin-dispersed preparations containing VEA or polysorbate 80 (PS-80)-solubilized solution of VEA were intraduodenally administered, VEA was hydrolyzed to d-alpha-tocopherol (VE) and was not detected in the plasma nor in the thoracic lymph. The maximum plasma concentration (Cmax) of VE after the intraduodenal administration of a preparation consisting of VEA, soybean phosphatidylcholine (PC) and medium-chain triglycerides (MCTG) (VEA/PC/MCTG, 5/16/1 by weight) was highest among the VEA preparations, and PS-80-solubilized solution gave the lowest Cmax. AUC of VE up to 24 h was also increased by the addition of MCTG to VEA/PC preparation. In the thoracic duct-fistula rat, the transport of VE into the thoracic lymph was increased by the administration of the VEA/PC/MCTG preparation significantly more than the VEA/PC preparation; the cumulative amounts of VE recovered in the thoracic lymph up to 24 h were 23.2 +/- 0.5% and 10.9 +/- 1.5% of dose, respectively. The plasma concentration of VE was not increased in the thoracic duct-fistula rat even after the intraduodenal administration of VEA preparations, suggesting that VE is not transported directly to the systemic circulation, but by way of the lymphatic route. The lymphatic transport of VE following the intraduodenal administration of VEA/PC/MCTG preparation was markedly diminished by the simultaneous administration of Pluronic L-81 emulsion, an inhibitor of chylomicron formation. It is suggested that the chylomicron is essential to the lymphatic transport of VE from VEA preparations.

  12. Behavior of heptavalent technetium in concentrated triflic acid under alpha-irradiation. Technetium-triflate complex characterized by X-ray absorption fine structure spectroscopy and DFT

    Energy Technology Data Exchange (ETDEWEB)

    Denden, Ibtihel; Blain, Guillaume; Fattahi, Massoud [SUBATECH Laboratory, Nantes (France); Roques, Jerome [Paris Sud Univ., Orsay (France). IPN Orsay; Poineau, Frederic [Nevada Univ., Las Vegas, NV (United States). Dept. of Chemistry and Biochemistry; Solari, Pier Lorenzo [CEA, Gif-sur-Yvette (France). DEN/DPC/SEARS; Schlegel, Michel L. [Synchrotron SOLEIL, Gif-sur-Yvette (France)

    2017-04-01

    The nature of the Tc species produced after the alpha-irradiation of Tc(VII) in concentrated triflic acid has been investigated by X-ray absorption fine structure (XAFS) spectroscopy and first principles calculations. Experimental and theoretical results are consistent with the formation of Tc{sup (V)}O(F{sub 3}CSO{sub 3}){sub 2}(H{sub 2}O){sub 2}{sup +}.

  13. Thermodynamic simulation of ammonia-water absorption refrigeration system

    Directory of Open Access Journals (Sweden)

    Sathyabhama A.

    2008-01-01

    Full Text Available The ammonia-water absorption refrigeration system is attracting increasing research interests, since the system can be powered by waste thermal energy, thus reducing demand on electricity supply. The development of this technology demands reliable and effective system simulations. In this work, a thermodynamic simulation of the cycle is carried out to investigate the effects of different operating variables on the performance of the cycle. A computer program in C language is written for the performance analysis of the cycle.

  14. Automated multispectra alpha spectrometer and data reduction system

    International Nuclear Information System (INIS)

    Hochel, R.C.

    1975-12-01

    A complete hardware and software package for the accumulation and rapid analysis of multiple alpha pulse height spectra has been developed. The system utilizes a 4096-channel analyzer capable of accepting up to sixteen inputs from solid-state surface barrier detectors via mixer-router modules. The analyzer is interfaced to a desk-top programmable calculator and thermal line printer. A chained software package including spectrum printout, peak analysis, plutonium-238 and plutonium-239 data reduction, and automatic energy calibration routines was written. With the chained program a complete printout, peak analysis, and plutonium data reduction of a 512-channel alpha spectrum are obtained in about three minutes with an accuracy within five percent of hand analyses

  15. A manual low background alpha beta counting system

    Energy Technology Data Exchange (ETDEWEB)

    Levison, S; German, U; Peled, O; Turgeman, S; Vangrovitz, U; Tirosh, D; Piestum, S; Assido, H [Israel Atomic Energy Commission, Beersheba (Israel). Nuclear Research Center-Negev

    1996-12-01

    An Alpha and Beta counting system consisting of a micro controller-based electronic unit and detectors assembly was developed. The radiation detection unit consists of two proportional detectors (a main detector and a cosmic-ray guard detector) which can be easily disassembled for decontamination or repair. The detectors are mounted in a manual operating sample changer shielded by 5 cm of lead. Simplicity of maintenance and functional operation were taken into consideration in the design. The electronic unit supplies the high voltage and enables the operational functions including controls anti alarms. Calculations of net cpm of Alpha and Beta counting are displayed and can be printed. RS-232 communication option enables connection to a computer and operation of more sophisticated programs for calculations and data storage in the future (authors).

  16. A manual low background alpha beta counting system

    International Nuclear Information System (INIS)

    Levison, S.; German, U.; Peled, O.; Turgeman, S.; Vangrovitz, U.; Tirosh, D.; Piestum, S.; Assido, H.

    1996-01-01

    An Alpha and Beta counting system consisting of a micro controller-based electronic unit and detectors assembly was developed. The radiation detection unit consists of two proportional detectors (a main detector and a cosmic-ray guard detector) which can be easily disassembled for decontamination or repair. The detectors are mounted in a manual operating sample changer shielded by 5 cm of lead. Simplicity of maintenance and functional operation were taken into consideration in the design. The electronic unit supplies the high voltage and enables the operational functions including controls anti alarms. Calculations of net cpm of Alpha and Beta counting are displayed and can be printed. RS-232 communication option enables connection to a computer and operation of more sophisticated programs for calculations and data storage in the future (authors)

  17. Simulation of solar-powered absorption cooling system

    Energy Technology Data Exchange (ETDEWEB)

    Atmaca, I.; Yigit, A. [Uludag Univ., Bursa (Turkey). Dept. of Mechanical Engineering

    2003-07-01

    With developing technology and the rapid increase in world population, the demand for energy is ever increasing. Conventional energy will not be enough to meet the continuously increasing need for energy in the future. In this case, renewable energy sources will become important. Solar energy is a very important energy source because of its advantages. Instead of a compressor system, which uses electricity, an absorption cooling system, using renewable energy and kinds of waste heat energy, may be used for cooling. In this study, a solar-powered, single stage, absorption cooling system, using a water-lithium bromide solution, is simulated. A modular computer program has been developed for the absorption system to simulate various cycle configurations and solar energy parameters for Antalya, Turkey. So, the effects of hot water inlet temperatures on the coefficient of performance (COP) and the surface area of the absorption cooling components are studied. In addition, reference temperatures which are the minimum allowable hot water inlet temperatures are determined and their effect on the fraction of the total load met by non-purchased energy (FNP) and the coefficient of performance are researched. Also, the effects of the collector type and storage tank mass are investigated in detail. (author)

  18. Backscatter absorption gas imaging systems and light sources therefore

    Science.gov (United States)

    Kulp, Thomas Jan [Livermore, CA; Kliner, Dahv A. V. [San Ramon, CA; Sommers, Ricky [Oakley, CA; Goers, Uta-Barbara [Campbell, NY; Armstrong, Karla M [Livermore, CA

    2006-12-19

    The location of gases that are not visible to the unaided human eye can be determined using tuned light sources that spectroscopically probe the gases and cameras that can provide images corresponding to the absorption of the gases. The present invention is a light source for a backscatter absorption gas imaging (BAGI) system, and a light source incorporating the light source, that can be used to remotely detect and produce images of "invisible" gases. The inventive light source has a light producing element, an optical amplifier, and an optical parametric oscillator to generate wavelength tunable light in the IR. By using a multi-mode light source and an amplifier that operates using 915 nm pump sources, the power consumption of the light source is reduced to a level that can be operated by batteries for long periods of time. In addition, the light source is tunable over the absorption bands of many hydrocarbons, making it useful for detecting hazardous gases.

  19. Recovering the systemic redshift of galaxies from their Lyman-alpha line profile

    Science.gov (United States)

    Verhamme, A.; Garel, T.; Ventou, E.; Contini, T.; Bouché, N.; Herenz, E. C.; Richard, J.; Bacon, R.; Schmidt, K. B.; Maseda, M.; Marino, R. A.; Brinchmann, J.; Cantalupo, S.; Caruana, J.; Clément, B.; Diener, C.; Drake, A. B.; Hashimoto, T.; Inami, H.; Kerutt, J.; Kollatschny, W.; Leclercq, F.; Patrício, V.; Schaye, J.; Wisotzki, L.; Zabl, J.

    2018-04-01

    The Lyman alpha (Lyα) line of Hydrogen is a prominent feature in the spectra of star-forming galaxies, usually redshifted by a few hundreds of km s-1 compared to the systemic redshift. This large offset hampers follow-up surveys, galaxy pair statistics and correlations with quasar absorption lines when only Lyα is available. We propose diagnostics that can be used to recover the systemic redshift directly from the properties of the Lyα line profile. We use spectroscopic observations of Lyman-Alpha Emitters (LAEs) for which a precise measurement of the systemic redshift is available. Our sample contains 13 sources detected between z ≈ 3 and z ≈ 6 as part of various Multi Unit Spectroscopic Explorer (MUSE) Guaranteed Time Observations (GTO). We also include a compilation of spectroscopic Lyα data from the literature spanning a wide redshift range (z ≈ 0 - 8). First, restricting our analysis to double-peaked Lyα spectra, we find a tight correlation between the velocity offset of the red peak with respect to the systemic redshift, V_peak^red, and the separation of the peaks. Secondly, we find a correlation between V_peak^red and the full width at half maximum of the Lyα line. Fitting formulas, to estimate systemic redshifts of galaxies with an accuracy of ≤100 km s-1 when only the Lyα emission line is available, are given for the two methods.

  20. Lack of dust in quasar absorption line systems

    International Nuclear Information System (INIS)

    Jura, M.

    1977-01-01

    It is stated that the origin of absorption line systems in quasars is still uncertain. Most such systems apparently have atomic hydrogen column densities of the order of 10 19 /cm 2 , but at least two quasars, 1331 + 170 and PHL957, have such strong Lyman α absorption lines that atomic hydrogen column densities of the order of 10 21 /cm 2 are indicated. It should be possible to observe the dust produced 2,200 A extinction feature as it is red shifted into the visible, and to determine whether absorption line systems are produced in spiral galaxies where the dust content is similar to that in the interstellar medium. It has been argued that the emission line regions of quasars generally lack dust and that towards PHL957 the 2,200 A feature is absent. The present author argues that dust similar to that found in the interstellar medium is not found towards the quasars 1331 + 170 and PHL957. This could explain why H 2 is not found towards PHL957, and it indicates that the absorption line systems in quasars are not produced in spiral galaxies similar to our own. It seems from the analysis presented that the dust-to-gas ratio towards 1331 + 170 is at least a factor of 20 less than in the interstellar medium, and there is no reason to suppose that this lack of dust results from a lack of metals It is concluded that there seems to be a lack of normal dust towards PHL957 by at least a factor of two; and that the absorption region towards 1331 + 170 and probably the region towards PHL957 are lacking dust similar to that in our own galaxy. This can explain the lack of H 2 in these systems. (U.K.)

  1. Radon Daughters Background Reduction in Alpha Particles Counting System

    International Nuclear Information System (INIS)

    Dadon, S. S.; Pelled, O.; Orion, I.

    2014-01-01

    The ABPC method is using a serially occurring events of the beta decay of the 214Bi fallow by alpha decay of the 214Po that take place almost simultaneously to detect the Pseudo Coincidence Event (PCE) from the RDP, and to subtract them from the gross alpha counts. 267 This work showed that it is possible to improve the efficiency of RDP background reduction, including subtracting the 218Po contribution by using the ABPC method based on a single solid state silicon PIPS detector. False counts percentage obtained at the output of the PCE circuit were smaller than 0.1%. The results show that the PCE circuit was not influenced by non RDP alpha emitters. The PCE system did not reduce the non PCE of the 218Po. After 20 minutes the 218Po was strongly decayed, and its contribution became negligible. In order to overcome this disadvantage, a mathematical matching calculations for the 214Po and the 218Po decay equations were employed, and a constant ratio of the APo214(0) / APo218(0) was obtained. This ratio can be used to estimate the count rate of the 218Po at the first 20 minutes, and to subtract it from the total count rate in order to obtain correct RDP reduction

  2. Surface structure of alpha-Fe sub 2 O sub 3 nanocrystal observed by O K-edge X-ray absorption spectroscopy

    CERN Document Server

    Zhang, J; Ibrahim, K; Abbas, M I; Ju, X

    2003-01-01

    X-ray absorption near edge structure (XANES) spectra is used as a probe of surface structure of alpha-Fe sub 2 O sub 3 nanocrystal, prepared by sol-gel method. We present O K-edge XANES of alpha-Fe sub 2 O sub 3 in nanocrystal and bulk by total electron yield at the photoemission station of Beijing Synchrotron Radiation Facility. The spectrum of alpha-Fe sub 2 O sub 3 shows a splitting of the pre-edge structure, which is interpreted as two subsets of Fe 3d t sub 2 sub g and e sub g orbitals in oxygen octahedral (O sub h) crystal field, and is also sensitive to long-range order effects. However, no distinguishable splitting of the pre-edge peak of nanocrystal alpha-Fe sub 2 O sub 3 is observed. This suggests that there exists the distorted octahedral coordination around Fe sites and also the long-range disorder due to the surface as compared with bulk alpha-Fe sub 2 O sub 3.

  3. Performance of a compact solar absorption cooling system

    International Nuclear Information System (INIS)

    Mulyanef; Kamaruzzaman Sopian

    2006-01-01

    This paper describes the performance of a compact solar absorption system. Purpose of compact solar is collector, generator and condenser in one unit. At present, two types of absorption cooling systems are marketed: the lithium bromide-water system and the ammonia-water system. In the lithium bromide-water system, water vapor is the refrigerant and ammonia water system where ammonia is the refrigerant. In addition, the ammonia-water system requires higher generator temperature 120 o C to 150 o C than a flat-plate solar collector can provide without special techniques. The lithium bromide-water system operates satisfactorily at a generator temperature of 75 o C to 100 o C, achievable by a flat-plate collector. The lithium bromide-water system also has a higher COP than the ammonia-water system. The disadvantage of the lithium bromide-water systems is that the evaporators cannot operate at temperature below 0 o C since the refrigerant is water. The Coefficient of Performance (COP) system is 0.62 and the concentration of LiBr-H 2 O is 50%

  4. Economic performance optimization of an absorption cooling system under uncertainty

    International Nuclear Information System (INIS)

    Gebreslassie, Berhane H.; Guillen-Gosalbez, Gonzalo; Jimenez, Laureano; Boer, Dieter

    2009-01-01

    Many of the strategies devised so far to address the optimization of energy systems are deterministic approaches that rely on estimated data. However, in real world applications there are many sources of uncertainty that introduce variability into the decision-making problem. Within this general context, we propose a novel approach to address the design of absorption cooling systems under uncertainty in the energy cost. As opposed to other approaches that optimize the expected performance of the system as a single objective, in our method the design task is formulated as a stochastic bi-criteria non-linear optimization problem that simultaneously accounts for the minimization of the expected total cost and the financial risk associated with the investment. The latter criterion is measured by the downside risk, which avoids the need to define binary variables thus improving the computational performance of the model. The capabilities of the proposed modeling framework and solution strategy are illustrated in a case study problem that addresses the design of a typical absorption cooling system. Numerical results demonstrate that the method presented allows to manage the risk level effectively by varying the area of the heat exchangers of the absorption cycle. Specifically, our strategy allows identifying the optimal values of the operating and design variables of the cycle that make it less sensitive to fluctuations in the energy price, thus improving its robustness in the face of uncertainty.

  5. Absorption in multiple scattering systems of coated spheres: design applications

    International Nuclear Information System (INIS)

    Stout, Brian; Andraud, Christine; Stout, Sophie; Lafait, Jacques

    2003-01-01

    We illustrate the utility of some recently derived transfer matrix methods for electromagnetic scattering calculations in systems composed of coated spherical scatterers. Any of the spherical coatings, cores, or host media may be composed of absorbing materials. Our formulae permit the calculation of local absorption in either orientation fixed or orientation averaged situations. We introduce methods for estimating the macroscopic transport properties of such media, and show how our scattering calculations can permit 'design' optimization of macroscopic properties

  6. β Absorption dust concentration monitor system based on the PLC

    International Nuclear Information System (INIS)

    Lian Dexing; Zhou Xiuliang; Liu Liyan; Li Zonglun; Cao Guanghui; Mao Wanchong

    2011-01-01

    To provide an on-line automatic system for dust concentration monitor is the purpose of this design.The system based on β-ray-absorption-method,employing PLC (Programmable Logic Controller) control technology, is presented. The user input parameter setup,the data acquisition and processing, and the communication with computer can be effectively regulated using the advanced PLC control technology. It has the features of high reliability, easy operation and easy maintenance, and the ability to monitor remotely. Measurement range: 0.1-1500 mg/m 3 , Accuracy: ±9%. The structure,working principle, electric circuit and software development of the system are introduced in detail. (authors)

  7. Monitoring and analysis of an absorption air-conditioning system

    Energy Technology Data Exchange (ETDEWEB)

    Perez de Vinaspre, M.; Bourouis, M.; Coronas, A. [Centro de Innovacion Tecnologica en Revalorizacion Energetica y Refrigeracion, Tarragona (Spain); Garcia, A.; Soto, V.; Pinazo, J.M. [E.T.S. Ingenieros Industriales, Valencia (Spain)

    2004-09-01

    In the last few years, high-energy consumption due to air-conditioning has led to a growing interest in the efficient use of energy in buildings. Although simulation programs have always been the main tools for analyzing energy in buildings, the reliability of their results is often compromised by a lack of certainty to reflect real conditions. The aim of this work is to monitorize and analyze the thermal behavior of an absorption-based air-conditioning installation of a university building in Tarragona, Spain. The existing monitoring system of the installation has been improved by implementing additional sensors and flow meters. The data has been stored during summer 2002 and used to assess the energy balance of the air-conditioning installation and the operational regime of the absorption chiller. [Author].

  8. Energy and exergy analyses of the diffusion absorption refrigeration system

    International Nuclear Information System (INIS)

    Yıldız, Abdullah; Ersöz, Mustafa Ali

    2013-01-01

    This paper describes the thermodynamic analyses of a DAR (diffusion absorption refrigeration) cycle. The experimental apparatus is set up to an ammonia–water DAR cycle with helium as the auxiliary inert gas. A thermodynamic model including mass, energy and exergy balance equations are presented for each component of the DAR cycle and this model is then validated by comparison with experimental data. In the thermodynamic analyses, energy and exergy losses for each component of the system are quantified and illustrated. The systems' energy and exergy losses and efficiencies are investigated. The highest energy and exergy losses occur in the solution heat exchanger. The highest energy losses in the experimental and theoretical analyses are found 25.7090 W and 25.4788 W respectively, whereas those losses as to exergy are calculated 13.7933 W and 13.9976 W. Although the values of energy efficiencies obtained from both the model and experimental studies are calculated as 0.1858, those values, in terms of exergy efficiencies are found 0.0260 and 0.0356. - Highlights: • The diffusion absorption refrigerator system is designed manufactured and tested. • The energy and exergy analyses of the system are presented theoretically and experimentally. • The energy and exergy losses are investigated for each component of the system. • The highest energy and exergy losses occur in the solution heat exchanger. • The energy and the exergy performances are also calculated

  9. The influence of the self-absorption on the measure of the total alpha activity in water samples

    International Nuclear Information System (INIS)

    Acena, M.L.; Gonzalez, J.A.; De Pablo, A.

    1981-01-01

    The self-absorption is an important difficulty in measuring α-activities in river water samples. A semiempirical equation for calculating the self-absorption versus sample thickness has been obtained. This equation is valid for the regular saline residues in spanish rivers and for thicknesses lower than 2 mg x cm -2 . This figure sets a limit for the amount of water to be evaporated from the sample. (author)

  10. Inhibition of systemic inflammation by central action of the neuropeptide alpha-melanocyte- stimulating hormone.

    Science.gov (United States)

    Delgado Hernàndez, R; Demitri, M T; Carlin, A; Meazza, C; Villa, P; Ghezzi, P; Lipton, J M; Catania, A

    1999-01-01

    The neuropeptide alpha-melanocyte stimulating hormone (alpha-MSH) reduces fever and acute inflammation in the skin when administered centrally. The aim of the present research was to determine whether central alpha-MSH can also reduce signs of systemic inflammation in mice with endotoxemia. Increases in serum tumor necrosis factor-alpha and nitric oxide, induced by intraperitoneal administration of endotoxin, were modulated by central injection of a small concentration of alpha-MSH. Inducible nitric oxide synthase (iNOS) activity and iNOS mRNA in lungs and liver were likewise modulated by central alpha-MSH. Lung myeloperoxidase activity, a marker of neutrophil infiltration, was increased in endotoxemic mice; the increase was significantly less in lungs of mice treated with central alpha-MSH. Intraperitoneal administration of the small dose of alpha-MSH that was effective centrally did not alter any of the markers of inflammation. In experiments using immunoneutralization of central alpha-MSH, we tested the idea that endogenous peptide induced within the brain during systemic inflammation modulates host responses to endotoxic challenge in peripheral tissues. The data showed that proinflammatory agents induced by endotoxin in the circulation, lungs, and liver were significantly greater after blockade of central alpha-MSH. The results suggest that anti-inflammatory influences of neural origin that are triggered by alpha-MSH could be used to treat systemic inflammation.

  11. Airborne differential absorption lidar system for water vapor investigations

    Science.gov (United States)

    Browell, E. V.; Carter, A. F.; Wilkerson, T. D.

    1981-01-01

    Range-resolved water vapor measurements using the differential-absorption lidar (DIAL) technique is described in detail. The system uses two independently tunable optically pumped lasers operating in the near infrared with laser pulses of less than 100 microseconds separation, to minimize concentration errors caused by atmospheric scattering. Water vapor concentration profiles are calculated for each measurement by a minicomputer, in real time. The work is needed in the study of atmospheric motion and thermodynamics as well as in forestry and agriculture problems.

  12. Industrial trigeneration using ammonia-water absorption refrigeration systems (AAR)

    International Nuclear Information System (INIS)

    Colonna, Piero; Gabrielli, Sandro

    2003-01-01

    In many industrial processes there is a simultaneous need for electric power and refrigeration at low temperatures. Examples are in the food and chemical industries. Nowadays the increase in fuel prices and the ecological implications are giving an impulse to energy technologies that better exploit the primary energy source and integrated production of utilities should be considered when designing a new production plant. The number of so-called trigeneration systems installations (electric generator and absorption refrigeration plant) is increasing. If low temperature refrigeration is needed (from 0 to -40 deg. C), ammonia-water absorption refrigeration plants can be coupled to internal combustion engines or turbogenerators. A thermodynamic system study of trigeneration configurations using a commercial software integrated with specifically designed modules is presented. The study analyzes and compares heat recovery from the primary mover at different temperature levels. In the last section a simplified economic assessment that takes into account disparate prices in European countries compares conventional electric energy supply from the grid and optimized trigeneration plants in one test case (10 MW electric power, 7000 h/year)

  13. New thermodynamical systems. Alternative of compression-absorption; Nouveaux systemes thermodynamiques. Alternative de la compression-absorption

    Energy Technology Data Exchange (ETDEWEB)

    Feidt, M.; Brunin, O.; Lottin, O.; Vidal, J.F. [Universite Henri Poincare Nancy, 54 - Vandoeuvre-les-Nancy (France); Hivet, B. [Electricite de France, 77 - Moret sur Loing (France)

    1996-12-31

    This paper describes a 5 years joint research work carried out by Electricite de France (EdF) and the ESPE group of the LEMTA on compression-absorption heat pumps. It shows how a thermodynamical model of machinery, completed with precise exchanger-reactor models, allows to simulate and dimension (and eventually optimize) the system. A small power prototype has been tested and the first results are analyzed with the help of the models. A real scale experiment in industrial sites is expected in the future. (J.S.) 20 refs.

  14. The calculation of the detection efficiency in the calibration of gross alpha-beta systems

    International Nuclear Information System (INIS)

    Marian Romeo Calin; Ileana Radulescu; Alexandru Erminiu Druker

    2013-01-01

    This paper presents a method for efficiency calibration of a measuring alpha-beta system PROTEAN ORTEC, MPC-2000-DP, using standard radioactive sources. The system is used to measure gross alpha-beta activity concentrations in environmental samples. The calculated efficiencies of detection were subsequently introduced in the system for two working geometries: measuring geometry-gross alpha-beta ε α g = 31,37 ± 0.25 (%)-the alpha efficiency and ε β g 44.94 ± 0.69 (%)-the beta efficiency, where the spillover factor is X talk g = 25.59 ± 0.50 (%) and measuring geometry up alpha-beta ε α u 36.23 ± 0.29 (%)-the alpha efficiency and ε β u = 48.53 ± 0.74 (%)-the beta efficiency, where the spillover factor is X talk u 31.08 ± 0.60 (%). (author)

  15. Absorption solar cooling systems using optimal driving temperatures

    International Nuclear Information System (INIS)

    Lecuona, Antonio; Ventas, Rubén; Vereda, Ciro; López, Ricardo

    2015-01-01

    The optimum instantaneous driving temperature of a solar cooling facility is determined along a day. The chillers compared use single effect cycles working with NH 3 /LiNO 3 , either conventional or hybridised by incorporating a low pressure booster compressor. Their performances are compared with a H 2 O/LiBr single effect absorption chiller as part of the same solar system. The results of a detailed thermodynamic cycle for the absorption chillers allow synthesizing them in a modified characteristic temperature difference model. The day accumulated solar cold production is determined using this optimum temperature during two sunny days in mid-July and mid-September, located in Madrid, Spain. The work shows the influences of operational variables and a striking result: selection of a time-constant temperature during all the day does not necessarily imply a substantial loss, being the temperature chosen a key parameter. The results indicate that the NH 3 /LiNO 3 option with no boosting offers a smaller production above-zero Celsius degrees temperatures, but does not require higher hot water driving temperatures than H 2 O/LiBr. The boosted cycle offers superior performance. Some operational details are discussed. - Highlights: • Instantaneous optimum driving temperature t g,op for solar cooling in Madrid. • 3 absorption cycles tested: H 2 O/LiBr and NH 3 /LiNO 3 single effect and hybrid. • The t g,op of the hybrid cycle is 16 °C lower than both single effect cycles. • The best fixed driving temperature can reach almost the same behaviour than t g,op

  16. Alpha-bungarotoxin binding to target cell in a developing visual system by carboxylated nanodiamond

    Energy Technology Data Exchange (ETDEWEB)

    Liu, K-K; Chen, P-Y; Lee, Tony J F; Chao, J-I [Institute of Pharmacology and Toxicology, Tzu Chi University, Hualien 970, Taiwan (China); Chen, M-F [Neuro-Medical Scientific Center, Tzu Chi General Hospital, Hualien 970, Taiwan (China); Cheng, C-L [Department of Physics, National Dong Hwa University, Hualien 974, Taiwan (China); Chang, C-C [Department of Biological Science and Technology, National Chiao Tung University, Hsin-Chu 300, Taiwan (China); Ho, Y-P [Department of Chemistry, National Dong Hwa University, Hualien 974, Taiwan (China)], E-mail: chaoji@mail.tcu.edu.tw

    2008-05-21

    system showing the binding of {alpha}-BTX to {alpha}7-nAChR.

  17. A low-cost vaporization-atomization system for atomic absorption spectrometry

    International Nuclear Information System (INIS)

    Bruhn F, C.G.; Ambiado V, F.; Woerner V, R.

    1990-01-01

    A low-cost vaporization-atomization system for atomic absorption spectrometry is developed as an alternative to the use of a graphite furnace in electrothermal atomic absorption spectrometry. (Author)

  18. The redshift number density evolution of Mg II absorption systems

    International Nuclear Information System (INIS)

    Chen Zhi-Fu

    2013-01-01

    We make use of the recent large sample of 17 042 Mg II absorption systems from Quider et al. to analyze the evolution of the redshift number density. Regardless of the strength of the absorption line, we find that the evolution of the redshift number density can be clearly distinguished into three different phases. In the intermediate redshift epoch (0.6 ≲ z ≲ 1.6), the evolution of the redshift number density is consistent with the non-evolution curve, however, the non-evolution curve over-predicts the values of the redshift number density in the early (z ≲ 0.6) and late (z ≳ 1.6) epochs. Based on the invariant cross-section of the absorber, the lack of evolution in the redshift number density compared to the non-evolution curve implies the galaxy number density does not evolve during the middle epoch. The flat evolution of the redshift number density tends to correspond to a shallow evolution in the galaxy merger rate during the late epoch, and the steep decrease of the redshift number density might be ascribed to the small mass of halos during the early epoch.

  19. The Bulk Elemental Composition of any Terrestrial Planets in the Alpha Centauri System

    Science.gov (United States)

    Lineweaver, C. H.; Schonberger, B. F. G.; Robles, J. A.

    2010-04-01

    Based on the devolatilization patterns in the solar system, and on the differences in the chemical compositions of the Sun and Alpha Centauri, we make estimates of the chemical composition of any Earth-like planets in the Alpha Centauri system.

  20. Optical performance and metallic absorption in nanoplasmonic systems.

    Science.gov (United States)

    Arnold, Matthew D; Blaber, Martin G

    2009-03-02

    Optical metrics relating to metallic absorption in representative plasmonic systems are surveyed, with a view to developing heuristics for optimizing performance over a range of applications. We use the real part of the permittivity as the independent variable; consider strengths of particle resonances, resolving power of planar lenses, and guiding lengths of planar waveguides; and compare nearly-free-electron metals including Al, Cu, Ag, Au, Li, Na, and K. Whilst the imaginary part of metal permittivity has a strong damping effect, field distribution is equally important and thus factors including geometry, real permittivity and frequency must be considered when selecting a metal. Al performs well at low permittivities (e.g. sphere resonances, superlenses) whereas Au & Ag only perform well at very negative permittivities (shell and rod resonances, LRSPP). The alkali metals perform well overall but present engineering challenges.

  1. Understanding Absorptive Capacities is an "Innovation Systems" Context

    DEFF Research Database (Denmark)

    Narula, Rajneesh

    2004-01-01

    This paper seeks to broaden our understanding of the concept underlying absorptive capacity atthe macro -level, paying particular attention to the growth and development perspectives. Weprovide definitions of absorptive and technological capacity, external technology flows,productivity growth....... We also undertake to explain how the nature ofabsorptive capacity changes with stages of economic development, and the importance of thedifferent aspects of absorptive capability at different stages. The relationship is not a linear one:the benefits that accrue from marginal increases in absorptive...... capability change over time.Finally, we provide a tentative and preliminary conceptual argument of how the different stagesof absorptive capacity are related to productivity growth, economic growth and employmentcreation.Key words: New economy, absorptive capacity, knowledge...

  2. Alpha: A real-time decentralized operating system for mission-oriented system integration and operation

    Science.gov (United States)

    Jensen, E. Douglas

    1988-01-01

    Alpha is a new kind of operating system that is unique in two highly significant ways. First, it is decentralized transparently providing reliable resource management across physically dispersed nodes, so that distributed applications programming can be done largely as though it were centralized. And second, it provides comprehensive, high technology support for real-time system integration and operation, an application area which consists predominately of aperiodic activities having critical time constraints such as deadlines. Alpha is extremely adaptable so that it can be easily optimized for a wide range of problem-specific functionality, performance, and cost. Alpha is the first systems effort of the Archons Project, and the prototype was created at Carnegie-Mellon University directly on modified Sun multiprocessor workstation hardware. It has been demonstrated with a real-time C(sup 2) application. Continuing research is leading to a series of enhanced follow-ons to Alpha; these are portable but initially hosted on Concurrent's MASSCOMP line of multiprocessor products.

  3. Development of low level alpha particle counting system

    International Nuclear Information System (INIS)

    Minobe, Masao; Kondo, Hiraku; Chinuki, Takashi; Hirano, Hiromichi

    1987-01-01

    Much attention has been paid to the trace analysis of uranium and thorium contained in the base material of LSI or VLSI, since the so-called ''soft-error'' of the memory device was known to be due to alpha particles emitted from these radioactive elements. We have developed an apparatus to meet the needs of estimating such a very small quantity of U and Th of the level of ppb, by directly counting alpha particles using a gas-flow type proportional counter. This method requires no sophisticated analytical skill, and the accuracy of the result is satisfactory. The instrumentation and some application of this apparatus are described. (author)

  4. Rapidly reconfigurable slow-light system based on off-resonant Raman absorption

    International Nuclear Information System (INIS)

    Vudyasetu, Praveen K.; Howell, John C.; Camacho, Ryan M.

    2010-01-01

    We present a slow-light system based on dual Raman absorption resonances in warm rubidium vapor. Each Raman absorption resonance is produced by a control beam in an off-resonant Λ system. This system combines all optical control of the Raman absorption and the low-dispersion broadening properties of the double Lorentzian absorption slow light. The bandwidth, group delay, and central frequency of the slow-light system can all be tuned dynamically by changing the properties of the control beam. We demonstrate multiple pulse delays with low distortion and show that such a system has fast switching dynamics and thus fast reconfiguration rates.

  5. Water absorption length measurement with the ANTARES optical beacon system

    International Nuclear Information System (INIS)

    Yepes-Ramirez, Harold

    2011-01-01

    ANTARES is a neutrino telescope located in the Mediterranean Sea with the aim of detecting high energy neutrinos of extra-terrestrial origin. It consists of a three dimensional array on 12 detection lines of photomultiplier tubes (PMTs) able to detect the Cherenkov light induced by muons produced in the interaction of neutrinos with the surrounding water and seabed. To reach the best angular resolution, good time and positioning calibrations are required. The propagation of Cherenkov photons strongly depends on the optical properties of the sea water, which has an impact on the reconstruction efficiency. The determination of the optical parameters, as the absorption and scattering lengths, is crucial to calculate properly the effective area and the angular resolution of the detector. The ANTARES optical beacon system consists of pulsed and fast, well controlled light sources distributed throughout the detector to carry out in situ the relative time calibration of the detector components. In this contribution we show some results on the sea water optical properties and their stability measured with the optical beacon system.

  6. Sulfur K-edge absorption spectroscopy on selected biological systems

    International Nuclear Information System (INIS)

    Lichtenberg, Henning

    2008-07-01

    Sulfur is an essential element in organisms. In this thesis investigations of sulfur compounds in selected biological systems by XANES (X-ray Absorption Near Edge Structure) spectroscopy are reported. XANES spectroscopy at the sulfur K-edge provides an excellent tool to gain information about the local environments of sulfur atoms in intact biological samples - no extraction processes are required. Spatially resolved measurements using a Kirkpatrick-Baez mirror focusing system were carried out to investigate the infection of wheat leaves by rust fungi. The results give information about changes in the sulfur metabolism of the host induced by the parasite and about the extension of the infection into visibly uninfected plant tissue. Furthermore, XANES spectra of microbial mats from sulfidic caves were measured. These mats are dominated by microbial groups involved in cycling sulfur. Additionally, the influence of sulfate deprivation and H 2 S exposure on sulfur compounds in onion was investigated. To gain an insight into the thermal degradation of organic material the influence of roasting of sulfur compounds in coffee beans was studied. (orig.)

  7. Generation of ER{alpha}-floxed and knockout mice using the Cre/LoxP system

    Energy Technology Data Exchange (ETDEWEB)

    Antonson, P., E-mail: per.antonson@ki.se [Department of Biosciences and Nutrition, Karolinska Institutet, Novum, SE-141 83 Huddinge (Sweden); Omoto, Y.; Humire, P. [Department of Biosciences and Nutrition, Karolinska Institutet, Novum, SE-141 83 Huddinge (Sweden); Gustafsson, J.-A. [Department of Biosciences and Nutrition, Karolinska Institutet, Novum, SE-141 83 Huddinge (Sweden); Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston, Houston, TX 77204 (United States)

    2012-08-10

    Highlights: Black-Right-Pointing-Pointer ER{alpha} floxed and knockout mice were generated. Black-Right-Pointing-Pointer Disruption of the ER{alpha} gene results in sterility in both male and female mice. Black-Right-Pointing-Pointer ER{alpha}{sup -/-} mice have ovaries with hemorrhagic follicles and hypoplastic uterus. Black-Right-Pointing-Pointer Female ER{alpha}{sup -/-} mice develop obesity. -- Abstract: Estrogen receptor alpha (ER{alpha}) is a nuclear receptor that regulates a range of physiological processes in response to estrogens. In order to study its biological role, we generated a floxed ER{alpha} mouse line that can be used to knock out ER{alpha} in selected tissues by using the Cre/LoxP system. In this study, we established a new ER{alpha} knockout mouse line by crossing the floxed ER{alpha} mice with Cre deleter mice. Here we show that genetic disruption of the ER{alpha} gene in all tissues results in sterility in both male and female mice. Histological examination of uterus and ovaries revealed a dramatically atrophic uterus and hemorrhagic cysts in the ovary. These results suggest that infertility in female mice is the result of functional defects of the reproductive tract. Moreover, female knockout mice are hyperglycemic, develop obesity and at the age of 4 months the body weight of these mice was more than 20% higher compared to wild type littermates and this difference increased over time. Our results demonstrate that ER{alpha} is necessary for reproductive tract development and has important functions as a regulator of metabolism in females.

  8. AN EFFICIENT ANALYSIS FOR ABSORPTION AND GAIN COEFFICIENTS IN 'SINGLE STEP-INDEX WAVEGUIDE'S BY USING THE ALPHA METHOD

    Directory of Open Access Journals (Sweden)

    Mustafa TEMİZ

    2008-02-01

    Full Text Available In this study, some design parameters such as normalized frequency and especially normalized propagation constant have been obtained, depending on some parameters which are functions of energy eigenvalues of the carriers such as electrons and holes confined in a single step-index waveguide laser (SSIWGL or single stepindex waveguide (SSIWG. Some optical expressions about the optical power and probability quantities for the active region and cladding layers of the SSIWG or SSIWGL have been investigated. Investigations have been undertaken in terms of these parameters and also individually the optical even and odd electric field waves with the lowest-modes were theoretically computed. Especially absorption coefficients and loss coefficients addition to some important quantities of the single step-index waveguide lasers for the even and odd electric field waves are evaluated.

  9. Antagonizing the alpha(4)beta(1) Integrin, but Not alpha(4)beta(7), Inhibits Leukocytic Infiltration of the Central Nervous System in Rhesus Monkey Experimental Autoimmune Encephalomyelitis

    NARCIS (Netherlands)

    Haanstra, Krista G.; Hofman, Sam O.; Estevao, Dave M. Lopes; Blezer, Erwin L. A.; Bauer, Jan; Yang, Li-Li; Wyant, Tim; Csizmadia, Vilmos; 't Hart, Bert A.; Fedyk, Eric R.

    2013-01-01

    The immune system is characterized by the preferential migration of lymphocytes through specific tissues (i.e., tissue tropism). Tissue tropism is mediated, in part, by the alpha(4) integrins expressed by T lymphocytes. The alpha(4)beta(1) integrin mediates migration of memory T lymphocytes into the

  10. New development of EPICS based data acquisition system for H-Alpha diagnostic

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Taegu, E-mail: glory@nfri.re.kr; Lee, Woongryol; Son, Souhun; Park, Jinseop

    2015-10-15

    Highlights: • The H-Alpha DAQ system was modified to measure the low current signal from the PMT. • We developed a new H-Alpha data acquisition system with a CPCI based digitizer. • We developed a signal conditioning box for converting the current to voltage. • The new signal condition box (SCB) has three input range level (400 nA, 1 μA and 2 μA). • It was successfully performed and stably operates more than the previous DAQ system. - Abstract: The H-Alpha diagnostic system has been developed to measure the line integrated intensity in the direction of toroidal and poloidal. The data acquisition (DAQ) system for H-Alpha diagnostics of the Korea Superconducting Tokamak Advanced Research (KSTAR) at the beginning of the first plasma in 2008 was developed with VME form factor digitizer in the Linux OS platform. The VME digitizer module of H-Alpha data acquisition system was modified to measure the low current signal from the photo-multiplier tubes (PMT). The input maximum current values of modified digitizer module are 400 nA and low current data is expressed as the value of the voltage between −10 V and +10 V. At first time, there was no problem to measure H-Alpha signal, but it could not measure the H-Alpha data signal as the KSTAR Plasma density increased. It exceeds digitizer input range, which means the H-Alpha signal is over 400 nA, so we should manually change the resistor on the digitizer board to measure the 400 nA over current. This is not easy to do and showed instability in the long time operation with high sampling data acquisition. In order to overcome these weak points, a new H-Alpha data acquisition system has been developed with a compact PCI (cPCI) based digitizer and a signal conditioning box for converting the current to voltage in the Linux OS platform. The new data acquisition system was developed based on Experimental Physics and Industrial Control System (EPICS) framework like other KSTAR diagnostics with standard framework (SFW

  11. New miniaturized alpha/beta spectrometric system for the surface contamination monitoring and radon personal dosimeter

    International Nuclear Information System (INIS)

    Streil, T.; Oeser, V.; Holfeld, G.

    1998-01-01

    The heart of the new miniaturized alpha/beta spectroscopic system is a Smart Card MCA having a 12 bit resolution and a 32 bit memory for each channel with the size of a cheque card. The system consists of a single or up to 12 alpha spectrometers in a battery powered casing with connectors for direct detector/amplifier module plugging. Surface contamination in the order of 1 Bq/cm 2 of 239 Pu can be measured. (M.D.)

  12. A new active absorption system and its performance to linear and non-linear waves

    DEFF Research Database (Denmark)

    Andersen, Thomas Lykke; Clavero, M.; Frigaard, Peter Bak

    2016-01-01

    Highlights •An active absorption system for wavemakers has been developed. •The theory for flush mounted gauges has been extended to cover also small gaps. •The new system has been validated in a wave flume with wavemakers in both ends. •A generation and absorption procedure for highly non-linear...

  13. Photoacoustic Experimental System to Confirm Infrared Absorption Due to Greenhouse Gases

    Science.gov (United States)

    Kaneko, Fumitoshi; Monjushiro, Hideaki; Nishiyama, Masayoshi; Kasai, Toshio; Harris, Harold H.

    2010-01-01

    An experimental system for detecting infrared absorption using the photoacoustic (PA) effect is described. It is aimed for use at high-school level to illustrate the difference in infrared (IR) absorption among the gases contained in the atmosphere in connection with the greenhouse effect. The experimental system can be built with readily…

  14. CONCEPT OF AUTOMATIC CONTROL SYSTEM FOR IMPROVING THE EFFICIENCY OF THE ABSORPTION REFRIGERATING UNITS

    Directory of Open Access Journals (Sweden)

    O. Titlova

    2016-12-01

    Full Text Available The general concept of the automatic control systems constructing for increasing the efficiency of the artificial cold production process in the absorption refrigerating units is substantiated. The described automatic control systems provides necessary degree of the ammonia vapor purification from the water in all absorption refrigerating units modes and minimizes heat loss from the dephlegmator surface.

  15. Chemical reactivity of {alpha}-isosaccharinic acid in heterogeneous alkaline systems

    Energy Technology Data Exchange (ETDEWEB)

    Glaus, M. A.; Loon, L. R. Van

    2009-05-15

    Cellulose degradation under alkaline conditions is of relevance for the mobility of many radionuclides in the near-field of a cementitious repository for radioactive waste, because metal-binding degradation products may be formed. Among these, {alpha}- isosaccharinic acid ({alpha}-ISA) is the strongest complexant. The prediction of the equilibrium concentration of {alpha}-ISA in cement pore water is therefore an important step in the assessment of the influence of cellulose degradation products on the speciation of radionuclides in such environments. The present report focuses on possible chemical transformation reactions of {alpha}-ISA in heterogeneous alkaline model systems containing either Ca(OH){sub 2} or crushed hardened cement paste. The transformation reactions were monitored by measuring the concentration of {alpha}-ISA by high performance anion exchange chromatography and the formation of reaction products by high performance ion exclusion chromatography. The overall loss of organic species from solution was monitored by measuring the concentration of non-purgeable organic carbon. The reactions were examined in diluted and compacted suspensions, at either 25 {sup o}C or 90 {sup o}C, and under anaerobic atmospheres obtained by various methods. It was found that {alpha}-ISA was transformed under all conditions tested to some extent. Reaction products, such as glycolate, formate, lactate and acetate, all compounds with less complexing strength than {alpha}-ISA, were detected. The amount of reaction products identified by the chromatographic technique applied was {approx} 50 % of the amount of {alpha}-ISA reacted. Sorption of {alpha}-ISA to Ca(OH){sub 2} contributed only to a minor extent to the loss of {alpha}-ISA from the solution phase. As the most important conclusion of the present work it was demonstrated that the presence of oxidising agents had a distinctive influence on the turnover of {alpha}-ISA. Under aerobic conditions {alpha}-ISA was

  16. Determination of alpha activity and fissile mass content in solid waste by systems using neutron interrogation

    International Nuclear Information System (INIS)

    Romeyer Dherbey, J.; Lacruche, G.; Berne, R.; Auge, J.; Martin Deidier, L.; Butez, M.

    1990-01-01

    The Quantitative control (determination of heavy nuclides and alpha activity) of alpha radioactive wastes is necessary, particularly to determine if the waste is in accordance with the surface storage limits. In order to reduce the uncertainty on the alpha activity resulting from unknown isotopic composition, inhomogeneity of heavy nuclides in the matrix, combination of several methods is necessary. In the paper we present the Cadarache development work in the NDA of solid waste using the Californium shuffler, 14 Mev neutron generator, and also passive techniques such as neutron emission measurement and gamma spectrometry. Experimental systems combining active and passive methods are presented (COSAC, BANCO, DANAIDE, PROMETHEE)

  17. Automation of a measurement systems of waste drum alpha activity

    International Nuclear Information System (INIS)

    Labarre, S.; Bardy, N.

    1985-10-01

    The alpha radiator activity in the two-hundred liter waste drums is found by an IN96, computerized analyzer of the society Intertechnique, from data delivered by a gamma detector (GeHP) and by neutron detection blocks (He counter). This computerized analyzer manages not only the drum rotation and position in front of the detector, but also the experimental data monitoring and their processing from specific programs (background noise, calibration, drum measurements). Thanks to this automation, the measurement number and their reliability are optimized [fr

  18. The effect of age on systemic absorption and systemic disposition of bupivacaine after subarachnoid administration

    Energy Technology Data Exchange (ETDEWEB)

    Veering, B.T.; Burm, A.G.; Vletter, A.A.; van den Hoeven, R.A.; Spierdijk, J. (Leiden Univ. Hospital (Netherlands))

    1991-02-01

    In order to evaluate the role of the pharmacokinetics of the age-related changes in the clinical profile of spinal anesthesia with bupivacaine, we studied the influence of age on the systemic absorption and systemic disposition of bupivacaine after subarachnoid administration in 20 male patients (22-81 yr), ASA Physical Status 1 or 2, by a stable isotope method. After subarachnoid administration of 3 ml 0.5% bupivacaine in 8% glucose, a deuterium-labeled analog (13.4 mg) was administered intravenously. Blood samples were collected for 24 h. Plasma concentrations of unlabeled and deuterium-labeled bupivacaine were determined with a combination of gas chromatography and mass fragmentography. Biexponential functions were fitted to the plasma concentration-time data of the deuterium-labeled bupivacaine. The systemic absorption was evaluated by means of deconvolution. Mono- and biexponential functions were fitted to the data of fraction absorbed versus time. The maximal height of analgesia and the duration of analgesia at T12 increased with age (r = 0.715, P less than 0.001; r = 0.640, P less than 0.01, respectively). In 18 patients the systemic absorption of bupivacaine was best described by a biexponential equation. The half-life of the slow systemic absorption process (r = -0.478; P less than 0.05) and the mean absorption time (r = -0.551; P less than 0.02) decreased with age. The total plasma clearance decreased with age (r = -0.650, P less than 0.002), whereas the mean residence time and terminal half-life increased with age (r = 0.597, P less than 0.01; r = 0.503, P less than 0.05).

  19. The effect of age on systemic absorption and systemic disposition of bupivacaine after subarachnoid administration

    International Nuclear Information System (INIS)

    Veering, B.T.; Burm, A.G.; Vletter, A.A.; van den Hoeven, R.A.; Spierdijk, J.

    1991-01-01

    In order to evaluate the role of the pharmacokinetics of the age-related changes in the clinical profile of spinal anesthesia with bupivacaine, we studied the influence of age on the systemic absorption and systemic disposition of bupivacaine after subarachnoid administration in 20 male patients (22-81 yr), ASA Physical Status 1 or 2, by a stable isotope method. After subarachnoid administration of 3 ml 0.5% bupivacaine in 8% glucose, a deuterium-labeled analog (13.4 mg) was administered intravenously. Blood samples were collected for 24 h. Plasma concentrations of unlabeled and deuterium-labeled bupivacaine were determined with a combination of gas chromatography and mass fragmentography. Biexponential functions were fitted to the plasma concentration-time data of the deuterium-labeled bupivacaine. The systemic absorption was evaluated by means of deconvolution. Mono- and biexponential functions were fitted to the data of fraction absorbed versus time. The maximal height of analgesia and the duration of analgesia at T12 increased with age (r = 0.715, P less than 0.001; r = 0.640, P less than 0.01, respectively). In 18 patients the systemic absorption of bupivacaine was best described by a biexponential equation. The half-life of the slow systemic absorption process (r = -0.478; P less than 0.05) and the mean absorption time (r = -0.551; P less than 0.02) decreased with age. The total plasma clearance decreased with age (r = -0.650, P less than 0.002), whereas the mean residence time and terminal half-life increased with age (r = 0.597, P less than 0.01; r = 0.503, P less than 0.05)

  20. Thermionic detection of the ionic fragments of continiuum-state pair absorption systems

    International Nuclear Information System (INIS)

    Hotop, R.; Niemax, K.; Richter, J.; Weber, K.H.

    1981-01-01

    Using a thermionic diode we have detected the ionic fragments formed by associative ionization and dissociation after continuum-state pair absorption processes in Cs-Cs and Cs-K systems. Assuming an ionization probability of unity of the excited species and calibrating the pair absorption bands by taking into account the known photoionization cross section of the atoms we found excellent agreement with data from classical absorption measurements. (orig.)

  1. Overproduction of alpha chains provides a proton-insensitive component to the bluefish hemoglobin system.

    Science.gov (United States)

    Bonaventura, Celia; Godette, Gerald; Stevens, Robert; Brenowitz, Michael; Henkens, Robert

    2005-12-09

    Expression of alpha and beta chains and their post-translational assembly into alpha(2)beta(2) tetramers is fundamental to the formation and function of most vertebrate hemoglobins. There is a strong evolutionary bias that favors expression of equal amounts of the two types of chains, because cooperativity, pH sensitivity, and anionic control of function occurs only for the alpha(2)beta(2) tetramers. Remarkably, an over-production of alpha chains, as in the pathological condition known as beta thalassemia in humans, is adaptive rather than pathological in the bluefish hemoglobin system. The thalassemia of the bluefish is a novel means of providing for oxygen uptake and delivery when low pH conditions incapacitate the highly pH-sensitive Root effect hemoglobins of the fish. Although fish often have pH-insensitive along with highly pH-sensitive hemoglobins, having pH-insensitive alpha chain monomers in circulation is an unusual structural variation. The role of bluefish alpha chains in oxygen transport is enabled by their remarkably lower oxygen affinity relative to human alpha chains. This is the first reported case of a thalassemic condition that is maintained in a species as an adaptive advantage.

  2. PGC-1alpha Deficiency Causes Multi-System Energy Metabolic Derangements: Muscle Dysfunction, Abnormal Weight Control and Hepatic Steatosis

    Directory of Open Access Journals (Sweden)

    Leone Teresa C

    2005-01-01

    Full Text Available The gene encoding the transcriptional coactivator peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha was targeted in mice. PGC-1alpha null (PGC-1alpha-/- mice were viable. However, extensive phenotyping revealed multi-system abnormalities indicative of an abnormal energy metabolic phenotype. The postnatal growth of heart and slow-twitch skeletal muscle, organs with high mitochondrial energy demands, is blunted in PGC-1alpha-/- mice. With age, the PGC-1alpha-/- mice develop abnormally increased body fat, a phenotype that is more severe in females. Mitochondrial number and respiratory capacity is diminished in slow-twitch skeletal muscle of PGC-1alpha-/- mice, leading to reduced muscle performance and exercise capacity. PGC-1alpha-/- mice exhibit a modest diminution in cardiac function related largely to abnormal control of heart rate. The PGC-1alpha-/- mice were unable to maintain core body temperature following exposure to cold, consistent with an altered thermogenic response. Following short-term starvation, PGC-1alpha-/- mice develop hepatic steatosis due to a combination of reduced mitochondrial respiratory capacity and an increased expression of lipogenic genes. Surprisingly, PGC-1alpha-/- mice were less susceptible to diet-induced insulin resistance than wild-type controls. Lastly, vacuolar lesions were detected in the central nervous system of PGC-1alpha-/- mice. These results demonstrate that PGC-1alpha is necessary for appropriate adaptation to the metabolic and physiologic stressors of postnatal life.

  3. PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.

    Directory of Open Access Journals (Sweden)

    Teresa C Leone

    2005-04-01

    Full Text Available The gene encoding the transcriptional coactivator peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha was targeted in mice. PGC-1alpha null (PGC-1alpha(-/- mice were viable. However, extensive phenotyping revealed multi-system abnormalities indicative of an abnormal energy metabolic phenotype. The postnatal growth of heart and slow-twitch skeletal muscle, organs with high mitochondrial energy demands, is blunted in PGC-1alpha(-/- mice. With age, the PGC-1alpha(-/- mice develop abnormally increased body fat, a phenotype that is more severe in females. Mitochondrial number and respiratory capacity is diminished in slow-twitch skeletal muscle of PGC-1alpha(-/- mice, leading to reduced muscle performance and exercise capacity. PGC-1alpha(-/- mice exhibit a modest diminution in cardiac function related largely to abnormal control of heart rate. The PGC-1alpha(-/- mice were unable to maintain core body temperature following exposure to cold, consistent with an altered thermogenic response. Following short-term starvation, PGC-1alpha(-/- mice develop hepatic steatosis due to a combination of reduced mitochondrial respiratory capacity and an increased expression of lipogenic genes. Surprisingly, PGC-1alpha(-/- mice were less susceptible to diet-induced insulin resistance than wild-type controls. Lastly, vacuolar lesions were detected in the central nervous system of PGC-1alpha(-/- mice. These results demonstrate that PGC-1alpha is necessary for appropriate adaptation to the metabolic and physiologic stressors of postnatal life.

  4. Residential solar air conditioning: Energy and exergy analyses of an ammonia–water absorption cooling system

    International Nuclear Information System (INIS)

    Aman, J.; Ting, D.S.-K.; Henshaw, P.

    2014-01-01

    Large scale heat-driven absorption cooling systems are available in the marketplace for industrial applications but the concept of a solar driven absorption chiller for air-conditioning applications is relatively new. Absorption chillers have a lower efficiency than compression refrigeration systems, when used for small scale applications and this restrains the absorption cooling system from air conditioning applications in residential buildings. The potential of a solar driven ammonia–water absorption chiller for residential air conditioning application is discussed and analyzed in this paper. A thermodynamic model has been developed based on a 10 kW air cooled ammonia–water absorption chiller driven by solar thermal energy. Both energy and exergy analyses have been conducted to evaluate the performance of this residential scale cooling system. The analyses uncovered that the absorber is where the most exergy loss occurs (63%) followed by the generator (13%) and the condenser (11%). Furthermore, the exergy loss of the condenser and absorber greatly increase with temperature, the generator less so, and the exergy loss in the evaporator is the least sensitive to increasing temperature. -- Highlights: • 10 kW solar thermal driven ammonia–water air cooled absorption chiller is investigated. • Energy and exergy analyses have been done to enhance the thermal performance. • Low driving temperature heat sources have been optimized. • The efficiencies of the major components have been evaluated

  5. A experimental system for the checking of the absorption of E.C.A.G. graphite

    International Nuclear Information System (INIS)

    Raievski, V.; Vidal, R.

    1958-01-01

    A system is described for measuring the mean absorption cross section in thermal neutrons of graphite. This system consists of a graphite stack containing a Ra-Be source and a BF3 counter. A cavity in the stack receives the graphite to be studied or the graphite standard. By comparing the counting rates their absorption ratio can be deduced. The measurement is performed on graphite rods which have been machined before being placed in the pile. It provides the possibility of detecting over a batch of 1 ton of graphite, in a single measurement, a difference in absorption of 0.1 milli barn. (author) [fr

  6. In vitro and in vivo percutaneous absorption of retinol from cosmetic formulations: Significance of the skin reservoir and prediction of systemic absorption

    International Nuclear Information System (INIS)

    Yourick, Jeffrey J.; Jung, Connie T.; Bronaugh, Robert L.

    2008-01-01

    The percutaneous absorption of retinol (Vitamin A) from cosmetic formulations was studied to predict systemic absorption and to understand the significance of the skin reservoir in in vitro absorption studies. Viable skin from fuzzy rat or human subjects was assembled in flow-through diffusion cells for in vitro absorption studies. In vivo absorption studies using fuzzy rats were performed in glass metabolism cages for collection of urine, feces, and body content. Retinol (0.3%) formulations (hydroalcoholic gel and oil-in-water emulsion) containing 3 H-retinol were applied and absorption was measured at 24 or 72 h. All percentages reported are % of applied dose. In vitro studies using human skin and the gel and emulsion vehicles found 0.3 and 1.3% retinol, respectively, in receptor fluid at 24 h. Levels of absorption in the receptor fluid increased over 72 h with the gel and emulsion vehicles. Using the gel vehicle, in vitro rat skin studies found 23% in skin and 6% in receptor fluid at 24 h, while 72-h studies found 18% in skin and 13% in receptor fluid. Thus, significant amounts of retinol remained in rat skin at 24 h and decreased over 72 h, with proportional increases in receptor fluid. In vivo rat studies with the gel found 4% systemic absorption of retinol after 24 h and systemic absorption did not increase at 72 h. Retinol remaining in rat skin after in vivo application was 18% and 13% of the applied dermal dose after 24 and 72 h, respectively. Similar observations were made with the oil-in water emulsion vehicle in the rat. Retinol formed a reservoir in rat skin both in vivo and in vitro. Little additional retinol was bioavailable after 24 h. Comparison of these in vitro and in vivo results for absorption through rat skin indicates that the 24-h in vitro receptor fluid value accurately estimated 24-h in vivo systemic absorption. Therefore, the best single estimate of retinol systemic absorption from in vitro human skin studies is the 24-h receptor fluid

  7. Cryogenic microcalorimeter system for ultra-high resolution alpha-particle spectrometry

    International Nuclear Information System (INIS)

    Rabin, Michael W.; Hoover, Andrew S.; Bacrania, Minesh K.; Croce, Mark P.; Hoteling, N.J.; Lamont, S.P.; Plionis, A.A.; Dry, D.E.; Ullom, J.N.; Bennett, D.A.; Horansky, R.; Kotsubo, V.; Cantor, R.

    2009-01-01

    Microcalorimeters have been shown to yield unsurpassed energy resolution for alpha spectrometry, up to 1.06 keV FWHM at 5.3 MeV. These detectors use a superconducting transition-edge sensor (TES) to measure the temperature change in an absorber from energy deposited by an interacting alpha particle. Our system has four independent detectors mounted inside a liquid nitrogen/liquid helium cryostat. An adiabatic demagnetization refrigerator (ADR) cools the detector stage to its operating temperature of 80 mK. Temperature regulation with ∼15 uK peak-to-peak variation is achieved by PID control of the ADR. The detectors are voltage-biased, and the current signal is amplified by a commercial SQUID readout system and digitized for further analysis, This paper will discuss design and operation of our microcalorimeter alpha spectrometer, and will show recent results.

  8. Cryogenic Microcalorimeter System for Ultra-High Resolution Alpha-Particle Spectrometry

    Science.gov (United States)

    Croce, M. P.; Bacrania, M. K.; Hoover, A. S.; Rabin, M. W.; Hoteling, N. J.; LaMont, S. P.; Plionis, A. A.; Dry, D. E.; Ullom, J. N.; Bennett, D. A.; Horansky, R. D.; Kotsubo, V.; Cantor, R.

    2009-12-01

    Microcalorimeters have been shown to yield unsurpassed energy resolution for alpha spectrometry, up to 1.06 keV FWHM at 5.3 MeV. These detectors use a superconducting transition-edge sensor (TES) to measure the temperature change in an absorber from energy deposited by an interacting alpha particle. Our system has four independent detectors mounted inside a liquid nitrogen/liquid helium cryostat. An adiabatic demagnetization refrigerator (ADR) cools the detector stage to its operating temperature of 80 mK. Temperature regulation with ˜15-μK peak-to-peak variation is achieved by PID control of the ADR. The detectors are voltage-biased, and the current signal is amplified by a commercial SQUID readout system and digitized for further analysis. This paper will discuss design and operation of our microcalorimeter alpha-particle spectrometer, and will show recent results.

  9. Automotive exhaust gas flow control for an ammonia–water absorption refrigeration system

    International Nuclear Information System (INIS)

    Rêgo, A.T.; Hanriot, S.M.; Oliveira, A.F.; Brito, P.; Rêgo, T.F.U.

    2014-01-01

    A considerable part of the energy generated by an automotive internal combustion engine is wasted as heat in the exhaust system. This wasted heat could be recovered and applied to power auxiliary systems in a vehicle, contributing to its overall energy efficiency. In the present work, the experimental analysis of an absorption refrigeration system was performed. The exhaust system of an automotive internal combustion engine was connected to the generator element of an absorption refrigeration system. The performance of the absorption refrigerator was evaluated as a function of the supplied heat. The use of a control strategy for the engine exhaust gas mass flow rate was implemented to optimize the system. Exhaust gas flow was controlled by step-motor actuated valves commanded by a microcontroller in which a proportional-integral control scheme was implemented. Information such as engine torque, speed, key temperatures in the absorption cycle, as well as internal temperatures of the refrigerator was measured in a transient regime. The results indicated that the refrigeration system exhibited better performance when the amount of input heat is controlled based on the temperature of the absorption cycle generator. It was possible to conclude that, by dynamically controlling the amount of input heat, the utilisation range of the absorption refrigeration system powered by exhaust gas heat could be expanded in order to incorporate high engine speed operating conditions. - Highlights: •An absorption refrigerator was driven by automotive exhaust gas heat. •A system for controlling the refrigeration system heat input was developed. •Excessive exhaust gas heat leads to ineffective operation of the refrigerator. •Control of refrigerator's generator temperature led to better performance. •The use of exhaust gas was possible for high engine speeds

  10. Design and construction of a system for determining Radon-222 through Alpha spectroscopy

    International Nuclear Information System (INIS)

    Bonifacio, J.; Iturbe, J.L.

    1992-02-01

    The study of the present work consists on designing a system to measure gas 222 Rn, using a surface barrier detector, in order to obtaining a more accuracy measure of this isotope by means of an alpha particle spectra and thus to try to avoid the influence of the radioactivity of the isotope descendants of short half life, which are also emitting of alpha particles, since by other methods its should make a series of corrections to obtain the real value of the radon activity. (Author)

  11. Emergency membrane contactor based absorption system for ammonia leaks in water treatment plants.

    Science.gov (United States)

    Shao, Jiahui; Fang, Xuliang; He, Yiliang; Jin, Qiang

    2008-01-01

    Abstract Because of the suspected health risks of trihalomethanes (THMs), more and more water treatment plants have replaced traditional chlorine disinfection process with chloramines but often without the proper absorption system installed in the case of ammonia leaks in the storage room. A pilot plant membrane absorption system was developed and installed in a water treatment plant for this purpose. Experimentally determined contact angle, surface tension, and corrosion tests indicated that the sulfuric acid was the proper choice as the absorbent for leaking ammonia using polypropylene hollow fiber membrane contactor. Effects of several operating conditions on the mass transfer coefficient, ammonia absorption, and removal efficiency were examined, including the liquid concentration, liquid velocity, and feed gas concentration. Under the operation conditions investigated, the gas absorption efficiency over 99.9% was achieved. This indicated that the designed pilot plant membrane absorption system was effective to absorb the leaking ammonia in the model storage room. The removal rate of the ammonia in the model storage room was also experimentally and theoretically found to be primarily determined by the ammonia suction flow rate from the ammonia storage room to the membrane contactor. The ammonia removal rate of 99.9% was expected to be achieved within 1.3 h at the ammonia gas flow rate of 500 m3/h. The success of the pilot plant membrane absorption system developed in this study illustrated the potential of this technology for ammonia leaks in water treatment plant, also paved the way towards a larger scale application.

  12. Remote Laser Evaporative Molecular Absorption Spectroscopy Sensor System

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose a sensor system capable of remotely probing the molecular composition of cold solar system targets (asteroids, comets, planets, moons), such as from a...

  13. Problems and precision of the alpha scintillation radon counting system

    International Nuclear Information System (INIS)

    Lucas, H.F.; Markuu, F.

    1985-01-01

    Variations in efficiency as large as 3% have been found for radon scintillation counting systems in which the photomultiplier tubes are sensitive to the thermoluminescent photons emitted by the scintillator after exposure to light or for which the resolution has deteriorated. The additional standard deviation caused by counting a radon chamber on multiple counting systems has been evaluated and the effect, if present, did not exceed about 0.1%. The chambers have been calibrated for the measurement of radon in air, and the standard deviation was equal to statistical counting error combined with a systematic error of 1.1%. 3 references, 2 figures, 2 tables

  14. Improvement and automatization of a proportional alpha-beta counting system - FAG

    International Nuclear Information System (INIS)

    German, U.; Levinson, S.; Pelled, O.; Shemesh, Y.; Assido, H.

    1997-01-01

    An alpha and beta counting system - FAG*, for planchette samples is operated at the Health Physics department's laboratory of the NRCN. The original operation mode of the system was based on manual tasks handled by the FHT1 100 electronics. An option for a basic computer keyboard operation was available too. A computer with an appropriate I/O card was connected to the system and a new operating program was developed which enables full automatic control of the various components. The program includes activity calculations and statistical checks as well as data management. A bar-code laser system for sample number reading was integrated into the Alpha-Beta automatic counting system. The sample identification by means of an attached bar-code label enables unmistakable and reliable attribution of results to the counted sample. authors)

  15. LiBr absorption systems integrated with high–efficiency IGSG plant

    DEFF Research Database (Denmark)

    Rokni, Masoud; Bellomare, Filippo

    2015-01-01

    vapor compression inverse cycles; waste heat from other systems can in fact be used as an efficient input instead of electrical energy. The opportunity to integrate Li-Br absorption systems with a high-efficiency energy plant was studied; rejected heat from a Municipal Solid Waste Gasification Plant......Over the last few years, the energy demand for cooling systems is increasing; different solutions in fact have been proposed in order to minimize the energetic and environmental impact of this trend. In this direction, absorption cooling systems are recognized as a valid alternative to traditional...

  16. Time evolution of a system of two alpha particles

    International Nuclear Information System (INIS)

    Baye, D.; Herschkowitz, D.

    1996-01-01

    Motivated by interpretations of a broad structure at 32.5 MeV in the 12 C( 12 C, 12 C(0 + 2 )) 12 C(0 + 2 ) doubly inelastic scattering cross sections in terms of linear chains of α particles, we study in a microscopic model with an exact account of antisymmetrization the time evolution of a system of two α clusters. The evolution of the system is obtained from a time-dependent variational principle and visualized with matter densities. Even in the most favourable case, an initial two-cluster structure completely disappears in less than 2.10 -22 s. This result casts doubts on the observability of longer α chains. (orig.)

  17. Stochastic systems driven by alpha-stable noises

    DEFF Research Database (Denmark)

    Ditlevsen, Ove Dalager; Ditlevsen, P.

    1998-01-01

    with observed data. In particular the tailsof the observed response distributions may even for linear systems be more fat than the tails obtained for Gaussianwhite noise input. Also the excitation may show jumps that cannot be modeled by Gaussian white noise. The paper supports the possibility of using...... the larger class of so-calledalpha-stable white noises to provide a better fit. A geophysical application concerning ice age climate variations is described....

  18. Alpha-Amylase Activity in Blood Increases after Pharmacological, But Not Psychological, Activation of the Adrenergic System.

    Directory of Open Access Journals (Sweden)

    Urs M Nater

    Full Text Available Alpha-amylase in both blood and saliva has been used as a diagnostic parameter. While studies examining alpha-amylase activity in saliva have shown that it is sensitive to physiological and psychological challenge of the adrenergic system, no challenge studies have attempted to elucidate the role of the adrenergic system in alpha-amylase activity in blood. We set out to examine the impact of psychological and pharmacological challenge on alpha-amylase in blood in two separate studies.In study 1, healthy subjects were examined in a placebo-controlled, double-blind paradigm using yohimbine, an alpha2-adrenergic antagonist. In study 2, subjects were examined in a standardized rest-controlled psychosocial stress protocol. Alpha-amylase activity in blood was repeatedly measured in both studies.Results of study 1 showed that alpha-amylase in blood is subject to stronger increases after injection of yohimbine compared to placebo. In study 2, results showed that there was no significant effect of psychological stress compared to rest.Alpha-amylase in blood increases after pharmacological activation of the adrenergic pathways suggesting that sympathetic receptors are responsible for these changes. Psychological stress, however, does not seem to have an impact on alpha-amylase in blood. Our findings provide insight into the mechanisms underlying activity changes in alpha-amylase in blood in healthy individuals.

  19. Increasing efficacy and reducing systemic absorption of brimonidine tartrate ophthalmic gels in rabbits.

    Science.gov (United States)

    Pang, Xiaochen; Li, Jiawei; Pi, Jiaxin; Qi, Dongli; Guo, Pan; Li, Nan; Wu, Yumei; Liu, Zhidong

    2018-03-01

    Systemic absorption of ocularly administered Brimonidine Tartrate has been reported to give rise to several side-effects. Hence, it has become crucial to develop a delivery system that could increase efficacy and reduce systemic absorption. Therefore, the present work aims to develop Brimonidine Tartrate gels with different concentrations (0.05%, 0.1%, and 0.2% w/v, respectively) using Carbopol 974 P and HPMC E4M, and compare the therapeutic efficacy and systemic absorption with that of eye drop (0.2%, w/v) by UPLC-MS/MS. The result of histological analysis did not show any morphological or structural changes after the administration of formulations. In vitro residence time studies demonstrated that the gels exhibited a better precorneal residence time as compared with the eye drop. The gels with lower concentrations of the drug (0.05% and 0.1%, w/v) could significantly decrease intraocular pressure (IOP) in both normal and water-loaded rabbits as compared to the eye drop. Finally, the values of the ratio of AUC (0→∞) in comparison to eye drop showed the gels with lower concentrations of Brimonidine Tartrate could decrease the systemic absorption. From the result, it can be concluded the 0.1% ophthalmic gel has a potential to improve therapeutic efficacy and reduce the potential toxicity caused by systemic absorption.

  20. A Method Validation for Determination of Gross Alpha and Gross Beta in Water Sample Using Low Background Gross Alpha/ Beta Counting System

    International Nuclear Information System (INIS)

    Zal Uyun Wan Mahmood; Norfaizal Mohamed; Nita Salina Abu Bakar

    2016-01-01

    Method validation (MV) for the measurement of gross alpha and gross beta activity in water (drinking, mineral and environmental) samples using Low Background Gross Alpha/ Beta Counting System was performed to characterize precision, accuracy and reliable results. The main objective of this assignment is to ensure that both the instrument and method always good performed and resulting accuracy and reliable results. Generally, almost the results of estimated RSD, z-score and U_s_c_o_r_e were reliable which are recorded as ≤30 %, less than 2 and less than 1.5, respectively. Minimum Detected Activity (MDA) was estimated based on the counting time of 100 minutes and present background counting value of gross alpha (0.01 - 0.35 cpm) and gross beta (0.50 - 2.18 cpm). Estimated Detection Limit (DL) was 0.1 Bq/ L for gross alpha and 0.2 Bq/ L for gross beta and expended uncertainty was relatively small of 9.77 % for gross alpha and 10.57 % for gross beta. Align with that, background counting for gross alpha and gross beta was ranged of 0.01 - 0.35 cpm and 0.50 - 2.18 cpm, respectively. While, sample volume was set at minimum of 500 mL and maximum of 2000 mL. These proven the accuracy and precision result that are generated from developed method/ technique is satisfactory and method is recommended to be used. Therefore, it can be concluded that the MV found no doubtful on the ability of the developed method. The test result showed the method is suitable for all types of water samples which are contained several radionuclides and elements as well as any impurities that interfere the measurement analysis of gross alpha and gross beta. (author)

  1. Air alpha monitoring device and system for the calibration of the track detectors

    International Nuclear Information System (INIS)

    Danis, A; Oncescu, M.; Ciubotariu, M.

    2001-01-01

    The radon measurement plays a critical role: - in monitoring the human health and safety, due to radon destructive health effects. Sustained exposures of humans to high concentration of radon, in fact to high concentrations of its decay products, can produce lung cancer; - in a variety of geophysical, geochemical, hydrological and atmospheric investigations, such as exploring resources of uranium or hydrocarbons. The transport of radon within the earth, waters and atmosphere makes it a useful tracer in these purposes. in both cases, the reliable long-term measurements are required because usual short-term variations in concentration need to be averaged. These variations are caused by factors such as relative humidity, temperature, atmospheric pressure and their seasonal variations, moisture content in the air, or ventilation in the dwelling or working places. The integrating measurement methods meet these requirements. Among them, the alpha track method is one of the adequate and useful method and it is used by authors in radon measurements in dwelling and working places including mines and house cellars. The best etched track alpha detector for radon measurements proved to be the detector CR-39 due to: - its sensitivity to alpha particles emitted by radon decay products; - its stability against various environmental factors; - its high degree of optical clarity, was used in a proper device for alpha monitoring in air. Its calibration for radon measurements was performed in the proper calibration system. The general descriptions and specifications were given previously. Only some characteristics of these devices are given here. For air alpha monitoring device: i) equipped with filter, during alpha exposure, the alpha particles of radon are registered in the etched track detector mounted inside (ρ Rn - track density); ii) without filter, the alpha particles emitted by radon + its alpha decay products/their aerosols are registered in the detector (ρ tot - track

  2. Orbital Eccentricity and the Stability of Planets in the Alpha Centauri System

    Science.gov (United States)

    Lissauer, Jack

    2016-01-01

    Planets on initially circular orbits are typically more dynamically stable than planets initially having nonzero eccentricities. However, the presence of a major perturber that forces periodic oscillations of planetary eccentricity can alter this situation. We investigate the dependance of system lifetime on initial eccentricity for planets orbiting one star within the alpha Centauri system. Our results show that initial conditions chosen to minimize free eccentricity can substantially increase stability compared to planets on circular orbits.

  3. Stability of Multi-Planet Systems in the Alpha Centauri System

    Science.gov (United States)

    Lissauer, Jack J.

    2017-01-01

    We evaluate the extent of the regions within the alpha Centauri AB star system where small planets are able to orbit for billion-year timescales (Quarles & Lissauer 2016, Astron. J. 151, 111), as well as how closely-spaced planetary orbits can be within those regions in which individual planets can survive. Although individual planets on low inclination, low eccentricity, orbits can survive throughout the habitable zones of both stars, perturbations from the companion star imply that the spacing of planets in multi-planet systems within the habitable zones of each star must be significantly larger than the spacing of similar multi-planet systems orbiting single stars in order to be long-lived. Because the binary companion induces a forced eccentricity upon the orbits of planets in orbit around either star, appropriately-aligned circumstellar orbits with small initial eccentricities are stable to slightly larger initial semimajor axes than are initially circular orbits. Initial eccentricities close to forced eccentricities can have a much larger affect on how closely planetary orbits can be spaced, and therefore on how many planets may remain in the habitable zones, although the required spacing remains significantly higher than for planets orbiting single stars.

  4. A bar-code reader for an alpha-beta automatic counting system - FAG

    International Nuclear Information System (INIS)

    Levinson, S.; Shemesh, Y.; Ankry, N.; Assido, H.; German, U.; Peled, O.

    1996-01-01

    A bar-code laser system for sample number reading was integrated into the FAG Alpha-Beta automatic counting system. The sample identification by means of an attached bar-code label enables unmistakable and reliable attribution of results to the counted sample. Installation of the bar-code reader system required several modifications: Mechanical changes in the automatic sample changer, design and production of new sample holders, modification of the sample planchettes, changes in the electronic system, update of the operating software of the system (authors)

  5. A bar-code reader for an alpha-beta automatic counting system - FAG

    Energy Technology Data Exchange (ETDEWEB)

    Levinson, S; Shemesh, Y; Ankry, N; Assido, H; German, U; Peled, O [Israel Atomic Energy Commission, Beersheba (Israel). Nuclear Research Center-Negev

    1996-12-01

    A bar-code laser system for sample number reading was integrated into the FAG Alpha-Beta automatic counting system. The sample identification by means of an attached bar-code label enables unmistakable and reliable attribution of results to the counted sample. Installation of the bar-code reader system required several modifications: Mechanical changes in the automatic sample changer, design and production of new sample holders, modification of the sample planchettes, changes in the electronic system, update of the operating software of the system (authors).

  6. Parametric analysis of an irreversible proton exchange membrane fuel cell/absorption refrigerator hybrid system

    International Nuclear Information System (INIS)

    Yang, Puqing; Zhang, Houcheng

    2015-01-01

    A hybrid system mainly consisting of a PEMFC (proton exchange membrane fuel cell) and an absorption refrigerator is proposed, where the PEMFC directly converts the chemical energy contained in the hydrogen into electrical and thermal energies, and the thermal energy is transferred to drive the bottoming absorption refrigerator for cooling purpose. By considering the existing irreversible losses in the hybrid system, the operating current density region of the PEMFC permits the absorption refrigerator to exert its function is determined and the analytical expressions for the equivalent power output and efficiency of the hybrid system under different operating conditions are specified. Numerical calculations show that the equivalent maximum power density and the corresponding efficiency of the hybrid system can be respectively increased by 5.3% and 6.8% compared to that of the stand-alone PEMFC. Comprehensive parametric analyses are conducted to reveal the effects of the internal irreversibility of the absorption refrigerator, operating current density, operating temperature and operating pressure of the PEMFC, and some integrated parameters related to the thermodynamic losses on the performance of the hybrid system. The model presented in the paper is more general than previous study, and the results for some special cases can be directly derived from this paper. - Highlights: • A CHP system composed of a PEMFC and an absorption refrigerator is proposed. • Current density region enables the absorption refrigerator to work is determined. • Multiple irreversible losses in the system are analytically characterized. • Maximum power density and corresponding efficiency can be increased by 5.3% and 6.8%. • Effects of some designing and operating parameters on the performance are discussed

  7. Moisture movement in cement-based repair systems monitored by X-ray absorption

    NARCIS (Netherlands)

    Lukovic, M.; Ye, G.; Schlangen, H.E.J.G.; van Breugel, K.

    2017-01-01

    In concrete repair systems, material properties in the repair material and interface are greatly influenced by the initial moisture content of the concrete (or mortar) substrate. In order to quantify moisture profiles inside the repair system, X-ray absorption was used. Preliminary studies are

  8. Safety, tolerability, and systemic absorption of dapivirine vaginal microbicide gel in healthy, HIV-negative women

    NARCIS (Netherlands)

    Nel, Annalene M.; Coplan, Paul; van de Wijgert, Janneke H.; Kapiga, Saidi H.; von Mollendorf, Claire; Geubbels, Eveline; Vyankandondera, Joseph; Rees, Helen V.; Masenga, Gileard; Kiwelu, Ireen; Moyes, Jocelyn; Smythe, Shanique C.

    2009-01-01

    To assess the local and systemic safety of dapivirine vaginal gel vs. placebo gel as well as the systemic absorption of dapivirine in healthy, HIV-negative women. Two prospective, randomized, double-blind, placebo-controlled phase I/II studies were conducted at five research centers, four in Africa

  9. Absorption of electromagnetic field energy by superfluid system of atoms with electric dipole moment

    International Nuclear Information System (INIS)

    Poluektov, Yu.M.

    2014-01-01

    The modified Gross-Pitaevskii equation which takes into account relaxation and interaction with alternating electromagnetic field is used to consider the absorption of electromagnetic field energy by a superfluid system on the assumption that the atoms has intrinsic dipole moment. It is shown that the absorption may be of a resonant behavior only if the dispersion curves of the electromagnetic wave and the excitations of the superfluid system intersect. It is remarkable that such a situation is possible if the superfluid system has a branch of excitations with the energy gap at low momenta. The experiments on absorption of microwaves in superfluid helium are interpreted as evidence of existence of such gap excitations. A possible modification of the excitation spectrum of superfluid helium in the presence of excitation branch with energy gap is dis-cussed qualitatively

  10. Photosynthetic antennae systems: energy transport and optical absorption

    International Nuclear Information System (INIS)

    Reineker, P.; Supritz, Ch.; Warns, Ch.; Barvik, I.

    2004-01-01

    The energy transport and the optical line shape of molecular aggregates, modeling bacteria photosynthetic light-harvesting systems (chlorosomes in the case of Chlorobium tepidum or Chloroflexus aurantiacus and LH2 in the case of Rhodopseudomonas acidophila) is investigated theoretically. The molecular units are described by two-level systems with an average excitation energy ε and interacting with each other through nearest-neighbor interactions. For LH2 an elliptical deformation of the ring is also allowed. Furthermore, dynamic and in the case of LH2 also quasi-static fluctuations of the local excitation energies are taken into account, simulating fast molecular vibrations and slow motions of the protein backbone, respectively. The fluctuations are described by Gaussian Markov processes in the case of the chlorosomes and by colored dichotomic Markov processes, with exponentially decaying correlation functions, with small (λ s ) and large (λ) decay constants, in the case of LH2

  11. Absorptive capacity, technological innovation, and product life cycle: a system dynamics model.

    Science.gov (United States)

    Zou, Bo; Guo, Feng; Guo, Jinyu

    2016-01-01

    While past research has recognized the importance of the dynamic nature of absorptive capacity, there is limited knowledge on how to generate a fair and comprehensive analytical framework. Based on interviews with 24 Chinese firms, this study develops a system-dynamics model that incorporates an important feedback loop among absorptive capacity, technological innovation, and product life cycle (PLC). The simulation results reveal that (1) PLC affects the dynamic process of absorptive capacity; (2) the absorptive capacity of a firm peaks in the growth stage of PLC, and (3) the market demand at different PLC stages is the main driving force in firms' technological innovations. This study also explores a sensitivity simulation using the variables of (1) time spent in founding an external knowledge network, (2) research and development period, and (3) knowledge diversity. The sensitivity simulation results show that the changes of these three variables have a greater impact on absorptive capacity and technological innovation during growth and maturity stages than in the introduction and declining stages of PLC. We provide suggestions on how firms can adjust management policies to improve their absorptive capacity and technological innovation performance during different PLC stages.

  12. Experimental results of a direct air-cooled ammonia–lithium nitrate absorption refrigeration system

    International Nuclear Information System (INIS)

    Llamas-Guillén, S.U.; Cuevas, R.; Best, R.; Gómez, V.H.

    2014-01-01

    Absorption thermal cooling systems driven by renewable energy are a viable option in order to reduce fossil fuel consumption and the associated emissions. This work shows the results of an air cooled absorption cooling prototype working with an ammonia–lithium nitrate mixture at high ambient temperatures. An absorption refrigeration system was designed and built. The prototype is a one stage ammonia–lithium nitrate air cooled chiller. The experimental system was instrumented to evaluate each component. This paper shows the operation conditions in the experimental unit as well as some of the heat loads encountered at different operating conditions. The system was operated successfully at ambient temperatures in the range of 25–35 °C. A series of test showed that even at ambient temperatures it can be operated at evaporator temperatures below 10 °C producing chilled water for air conditioning applications such as radiative cooling panels. The system proved to stabilize very quickly and no risk of crystallization was encountered so the first results are promising in order to continue with the development of a more advanced prototype. - Highlights: •Experimental results of a direct air-cooled ammonia–lithium nitrate system. •The prototype is a one stage ammonia–lithium nitrate air cooled chiller. •The absorption system was operated successfully at ambient temperatures. •Cooling loads of 4.5 kW were reached in the chilled water side

  13. Transient infrared absorption of t-CH3C(O)OO, c-CH3C(O)OO, and alpha-lactone recorded in gaseous reactions of CH3CO and O2.

    Science.gov (United States)

    Chen, Sun-Yang; Lee, Yuan-Pern

    2010-03-21

    A step-scan Fourier-transform infrared spectrometer coupled with a multipass absorption cell was utilized to monitor the transient species produced in gaseous reactions of CH(3)CO and O(2); IR absorption spectra of CH(3)C(O)OO and alpha-lactone were observed. Absorption bands with origins at 1851+/-1, 1372+/-2, 1169+/-6, and 1102+/-3 cm(-1) are attributed to t-CH(3)C(O)OO, and those at 1862+/-3, 1142+/-4, and 1078+/-6 cm(-1) are assigned to c-CH(3)C(O)OO. A weak band near 1960 cm(-1) is assigned to alpha-lactone, cyc-CH(2)C(=O)O, a coproduct of OH. These observed rotational contours agree satisfactorily with simulated bands based on predicted rotational parameters and dipole derivatives, and observed vibrational wavenumbers agree with harmonic vibrational wavenumbers predicted with B3LYP/aug-cc-pVDZ density-functional theory. The observed relative intensities indicate that t-CH(3)C(O)OO is more stable than c-CH(3)C(O)OO by 3+/-2 kJ mol(-1). Based on these observations, the branching ratio for the OH+alpha-lactone channel of the CH(3)CO+O(2) reaction is estimated to be 0.04+/-0.01 under 100 Torr of O(2) at 298 K. A simple kinetic model is employed to account for the decay of CH(3)C(O)OO.

  14. Prototype explosives detection system based on nuclear resonance absorption in nitrogen

    International Nuclear Information System (INIS)

    Morgado, R.E.; Arnone, G.J.; Cappiello, C.C.

    1996-01-01

    A laboratory prototype system has been developed for the experimental evaluation of an explosives detection technique based on nuclear resonance absorption of gamma rays in nitrogen. Major subsystems include a radiofrequency quadrupole proton accelerator and associated beam transport system, a high-power gamma-ray production target, an airline-luggage tomographic inspection system, and an image- processing/detection-alarm subsystem. The detection system performance, based on a limited experimental test, is reported

  15. Real time alpha value measurement with Feynman-α method utilizing time series data acquisition on low enriched uranium system

    International Nuclear Information System (INIS)

    Tonoike, Kotaro; Yamamoto, Toshihiro; Watanabe, Shoichi; Miyoshi, Yoshinori

    2003-01-01

    As a part of the development of a subcriticality monitoring system, a system which has a time series data acquisition function of detector signals and a real time evaluation function of alpha value with the Feynman-alpha method was established, with which the kinetic parameter (alpha value) was measured at the STACY heterogeneous core. The Hashimoto's difference filter was implemented in the system, which enables the measurement at a critical condition. The measurement result of the new system agreed with the pulsed neutron method. (author)

  16. Design and construction of a system to analyze Radon 222 by means of alpha spectroscopy

    International Nuclear Information System (INIS)

    Martinez, J.B.

    1991-01-01

    Design and construction of a system to measure gaseous Radon 222 which arise from a source of Radium 226 electrodeposited in a stainless disc is described. Such a system allows to differentiate the energies of radium where they come from, as well as energies of daughter products. In this way it is possible to have a more precise measure of the alpha activity of this isotope. The system was constructed in a stainless steel hermetic container made of the camera, a cape and a valve, the used sample was a standards of Radium 226 attained from carnotite ore. The Radon 222 alpha particles, as well as the alpha particles of its decay products namely Polonium 210. Polonium 218 and Polonium 214 were identified by a surface barrier detector. The results in this manner obtained shows clearly well definite peaks of Radon 222 and also peaks of the Radon 222 daughter products with energies of 5.43, 5.31, 6.0 and 7.69 Mev respectively. The system allows to separate and to indentify the energies of Radon and its daughter products coming directly from a standard solid sample of Radium 226 (Author)

  17. Extrasynaptic location of alpha-2 and noninnervated beta-2 adrenoceptors in the vascular system of the pithed normotensive rat

    NARCIS (Netherlands)

    Wilffert, B.; Timmermans, P.B.M.W.M.; Van Zwieten, P.A.

    1982-01-01

    The receptors involved in the pressor and tachycardic effects of catecholamines applied systemically or released from sympathetic nerve endings were compared. Intravenously administered (-)-epinephrine activated alpha-1, alpha-2, beta-1 and beta-2 adrenoceptors as demonstrated in pithed rats, using

  18. Theory of Feynman-alpha technique with masking window for accelerator-driven systems

    International Nuclear Information System (INIS)

    Kitamura, Yasunori; Misawa, Tsuyoshi

    2017-01-01

    Highlights: • A theory of the modified Feynman-alpha technique for the ADS was developed. • The experimental conditions under which this technique works were discussed. • It is expected this technique is applied to the subcriticality monitor for the ADS. - Abstract: Recently, a modified Feynman-alpha technique for the subcritical system driven by periodically triggered neutron bursts was developed. One of the main features of this technique is utilization of a simple formula that is advantageous in evaluating the subcriticality. However, owing to the absence of the theory of this technique, this feature has not been fully investigated yet. In the present study, a theory of this technique is provided. Furthermore, the experimental conditions under which the simple formula works are discussed to apply this technique to the subcriticality monitor for the accelerator-driven system.

  19. ALPHA/PHOENIX-P/ANC system validation for Angra-1 neutronic calculations

    International Nuclear Information System (INIS)

    Ponzoni Filho, Pedro; Sato, Sadakatu; Santos, Teresinha Ipojuca Cardoso; Fernandes, Vanderlei Borba; Fetterman, R.J.

    1995-01-01

    The ALPHA/PHOENIX-P/ANC (APA) code package is an advanced neutronic calculation system for pressurized water reactor (PWR). PHOENIX-P generates the required cross sections for the fuel, burnable absorbers, control rods and baffle/reflector region. The ALPHA code is used to automate the generation of these cross-sections as well as process the PHOENIX-P results to generate the ANC model input. ANC is a three dimensional advanced nodal code used for the modeling of the, depletion of the fuel in the core, and for the calculation of power distributions, rod worths and other reactivity parameters. This paper provides brief overview of the APA methodology for reload core design of Angra Unit 1 Cycles 1 and 2. Results included are predicted power distributions, control rod worths and other reactivity parameters compared to plant measurements. These results demonstrate that the APA system can be used for the reload core design. (author). 7 refs, 9 figs

  20. ALPHA/PHOENIX-P/ANC system validation for Angra-1 neutronic calculations

    Energy Technology Data Exchange (ETDEWEB)

    Ponzoni Filho, Pedro; Sato, Sadakatu; Santos, Teresinha Ipojuca Cardoso; Fernandes, Vanderlei Borba [FURNAS, Rio de Janeiro, RJ (Brazil); Fetterman, R.J. [Westinghouse Electric Corp., Pittsburgh, PA (United States)

    1995-12-31

    The ALPHA/PHOENIX-P/ANC (APA) code package is an advanced neutronic calculation system for pressurized water reactor (PWR). PHOENIX-P generates the required cross sections for the fuel, burnable absorbers, control rods and baffle/reflector region. The ALPHA code is used to automate the generation of these cross-sections as well as process the PHOENIX-P results to generate the ANC model input. ANC is a three dimensional advanced nodal code used for the modeling of the, depletion of the fuel in the core, and for the calculation of power distributions, rod worths and other reactivity parameters. This paper provides brief overview of the APA methodology for reload core design of Angra Unit 1 Cycles 1 and 2. Results included are predicted power distributions, control rod worths and other reactivity parameters compared to plant measurements. These results demonstrate that the APA system can be used for the reload core design. (author). 7 refs, 9 figs.

  1. Performance modelling and simulation of an absorption solar cooling system for Malaysia

    International Nuclear Information System (INIS)

    Assilzadeh, F.; Ali, Y.; Kamaruzzaman Sopian

    2006-01-01

    Solar radiation contains huge amounts of energy and is required for almost all the natural processes on earth. Solar-powered air-conditioning has many advantages when compared to normal electricity system. This paper presents a solar cooling system that has been designed for Malaysia and other tropical regions using evacuated tube solar collector and LiBr absorption system. A modelling and simulation of absorption solar cooling system is modeled in Transient System Simulation (TRNSYS) environment. The typical meteorological year file containing the weather parameters is used to simulate the system. Then a system optimization is carried out in order to select the appropriate type of collector, the optimum size of storage tank, the optimum collector slope and area and the optimum thermostat setting of the auxiliary boiler

  2. Preliminary aseismic analysis on bolts of driving mechanism in absorption sphere shutdown system

    International Nuclear Information System (INIS)

    Chen Feng; Li Tianjin; Zhang Zhengming; Huang Zhiyong; Bo Hanliang

    2012-01-01

    The absorption sphere shutdown system performs an important role in reactivity regulating and control. Driving mechanism is a set of key mechanical moving parts which is used to control falling of absorption spheres in absorption sphere shutdown system. It is about 5 m for driving mechanism with the slim structure, which is connected with the upper supported plate of metal reactor internals through storage vessel with bolts. Both the storage vessel and driving mechanism are equipment of seismic classification I. It is significant to calculate and check the bolts strength of driving mechanism. In this paper, complicate structure of driving mechanism was simplified to three variable cross sections and statically indeterminate problem was solved. The bolts at the bottom and on the top of the storage vessel were calculated and checked. The preliminary results indicate that the bolts strength is reliable and safe, and the supporting force at the most weak point of driving mechanism is as well obtained. (authors)

  3. LiCl Dehumidifier LiBr absorption chiller hybrid air conditioning system with energy recovery

    Science.gov (United States)

    Ko, Suk M.

    1980-01-01

    This invention relates to a hybrid air conditioning system that combines a solar powered LiCl dehumidifier with a LiBr absorption chiller. The desiccant dehumidifier removes the latent load by absorbing moisture from the air, and the sensible load is removed by the absorption chiller. The desiccant dehumidifier is coupled to a regenerator and the desiccant in the regenerator is heated by solar heated hot water to drive the moisture therefrom before being fed back to the dehumidifier. The heat of vaporization expended in the desiccant regenerator is recovered and used to partially preheat the driving fluid of the absorption chiller, thus substantially improving the overall COP of the hybrid system.

  4. Airborne differential absorption lidar system for measurements of atmospheric water vapor and aerosols

    Science.gov (United States)

    Carter, Arlen F.; Allen, Robert J.; Mayo, M. Neale; Butler, Carolyn F.; Grossman, Benoist E.; Ismail, Syed; Grant, William B.; Browell, Edward V.; Higdon, Noah S.; Mayor, Shane D.; hide

    1994-01-01

    An airborne differential absorption lidar (DIAL) system has been developed at the NASA Langley Research Center for remote measurements of atmospheric water vapor (H2O) and aerosols. A solid-state alexandrite laser with a 1-pm linewidth and greater than 99.85% spectral purity was used as the on-line transmitter. Solid-state avalanche photodiode detector technology has replaced photomultiplier tubes in the receiver system, providing an average increase by a factor of 1.5-2.5 in the signal-to-noise ratio of the H2O measurement. By incorporating advanced diagnostic and data-acquisition instrumentation into other subsystems, we achieved additional improvements in system operational reliability and measurement accuracy. Laboratory spectroscopic measurements of H2O absorption-line parameters were performed to reduce the uncertainties in our knowledge of the absorption cross sections. Line-center H2O absorption cross sections were determined, with errors of 3-6%, for more than 120 lines in the 720-nm region. Flight tests of the system were conducted during 1989-1991 on the NASA Wallops Flight Facility Electra aircraft, and extensive intercomparison measurements were performed with dew-point hygrometers and H2O radiosondes. The H2O distributions measured with the DIAL system differed by less than 10% from the profiles determined with the in situ probes in a variety of atmospheric conditions.

  5. The applicability of ALPHA/PHOENIX/ANC nuclear design code system on Korean standard PWR's

    International Nuclear Information System (INIS)

    Lee, Kookjong; Choi, Kie-Yong; Lee, Hae-Chan; Roh, Eun-Rae

    1996-01-01

    For the Korean Standard Nuclear Power Plant (KSNPP) designed based on Combustion Engineering (CE) System 80, the Westinghouse nuclear design code system ALPHA/PHOENIX/ANC was applied to the follow-up design of initial and reload core of KSNPP. The follow-up design results of Yonggwang Unit 3 Cycle 1, 2 and Yonggwang Unit 4 Cycle 1 have shown good agreements with the measured data. The assemblywise power distributions have shown less than 2% average differences and critical boron concentrations have shown less than 20 ppm differences. All the low power physics test parameters are in good agreement. Consequently, APA design code system can be applied to KNSPP cores. (author)

  6. The pharmacokinetic profile of tamsulosin oral controlled absorption system (OCAS((R)))

    NARCIS (Netherlands)

    Michel, M. C.; Korstanje, C.; Krauwinkel, W.; Kuipers, M.

    2005-01-01

    Context: A new formulation of tamsulosin for the treatment of lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH) has been developed. This formulation uses the proprietary oral controlled absorption system (OCAS(R)) technology which has the potential to better control

  7. Nonlinear absorption of fullerene- and nanotubes-doped liquid crystal systems

    Czech Academy of Sciences Publication Activity Database

    Kamanina, N.; Reshak, Ali H; Vasiliev, P.Y.; Vangonen, A. I.; Studeonov, V. I.; Usanov, Y. E.; Ebothe, J.; Gondek, E.; Wojcik, W.; Danel, A.

    2009-01-01

    Roč. 41, č. 3 (2009), s. 391-394 ISSN 1386-9477 Institutional research plan: CEZ:AV0Z60870520 Keywords : nonlinear absorption properties * organic electrooptical systems * liquid crystal * fullerene s * nanotubes * PVK-derivatives Subject RIV: BO - Biophysics Impact factor: 1.177, year: 2009

  8. Study of an absorption machine for an ammonia-water system ...

    African Journals Online (AJOL)

    This paper deals with Study of an absorption machine for an ammonia-water system decentralized trigeneration. The effects of evaporator, absorber and boiler temperature on the coefficient of performance of this cycle investigate. Simulation results show that with increasing the evaporator and absorber temperature the ...

  9. Mapping Quantitatively Regional Drug Absorption in Canines with IntelliCap System

    NARCIS (Netherlands)

    Becker, D.; Schütz, H.; Beyerbach, A.; Zou, H.; Shimizu, J.; Iordanov, V.P.

    2011-01-01

    Quantitative regional absorption of a drug under development was studied by using the novel IntelliCap system. IntelliCap is an orally swallowable programmable drug delivery capsule and capable of real-time monitoring of physiological conditions (pH, temperature), consequently allowing localization

  10. Nature and statistical properties of quasar associated absorption systems in the XQ-100 Legacy Survey

    DEFF Research Database (Denmark)

    Perrotta, Serena; D'Odorico, Valentina; Prochaska, J. Xavier

    2016-01-01

    We statistically study the physical properties of a sample of narrow absorption line (NAL) systems looking for empirical evidences to distinguish between intrinsic and intervening NALs without taking into account any a priori definition or velocity cut-off. We analyze the spectra of 100 quasars...

  11. How to take absorptive surfaces into account when designing outdoor sound reinforcement systems

    DEFF Research Database (Denmark)

    Rasmussen, Karsten bo

    1996-01-01

    When sound reinforcement systems are used outdoors, absorptive surfaces are usually present along the propagation path of the sound. This may lead to a very significant colouration of the spectrum received by the audience. The colouration depends on the location and directivity of the loudspeaker......, the nature of the absorptive surface (eg grass) and the location of the audience. It is discussed how this effect may be calculated and numerical examples are shown. The results show a significant colouration and attenuation of the sound due to grass-covered surfaces....

  12. Efficient atom localization via probe absorption in an inverted-Y atomic system

    Science.gov (United States)

    Wu, Jianchun; Wu, Bo; Mao, Jiejian

    2018-06-01

    The behaviour of atom localization in an inverted-Y atomic system is theoretically investigated. For the atoms interacting with a weak probe field and several orthogonal standing-wave fields, their position information can be obtained by measuring the probe absorption. Compared with the traditional scheme, we couple the probe field to the transition between the middle and top levels. It is found that the probe absorption sensitively depends on the detuning and strength of the relevant light fields. Remarkably, the atom can be localized at a particular position in the standing-wave fields by coupling a microwave field to the transition between the two ground levels.

  13. Portable Instrument to Measure CDOM Light Absorption in Aquatic Systems: WPI Success Story

    Science.gov (United States)

    2001-01-01

    World Precision Instruments, Inc. (WPI), of Sarasota, FL, in collaboration with NASA's John C. Stennis Space Center, has developed an innovative instrument to accurately measure Colored Dissolved Organic Matter (CDOM) absorption in the field. This successful collaboration has culminated in an exciting new device, called the UltraPath, now commercially available through WPI. Traditional methods of measuring absorption of dissolved materials require special handling and storage prior to measurement. Use of laboratory spectrophotometers as the measuring devices have proven time consuming, cumbersome, and delicate to handle. The UltraPath provides a low-cost, highly sensitive, rugged, portable system that is capable of high sensitivity measurements in widely divergent waters.

  14. Ab-sorption machines for heating and cooling in future energy systems - Final report

    Energy Technology Data Exchange (ETDEWEB)

    Tozer, R.; Gustafsson, M.

    2000-12-15

    After the Executive Summary and a brief introductory chapter, Chapter 2, Sorption Technologies for Heating and Cooling in Future Energy Systems, reviews the main types of sorption systems. Chapter 3, Market Segmentation, then considers the major segments of the market including residential, commercial/institutional and industrial, and the types of sorption hardware most suitable to each. The highly important residential and commercial/institutional markets are mostly concerned with air-conditioning of buildings. More applications are identified and discussed for the industrial market, including refrigeration, food-storage cooling, process cooling, and process heating at various temperature ranges from hot water for hand-washing to high-temperature (greater than 130C). Other interesting industrial applications are absorption cooling or heating combined with co-generation, desiccant cooling, gas turbine inlet air cooling, combining absorption chillers with district heating systems, direct-fired absorption heat pumps (AHPs), and a closed greenhouse concept being developed for that economically important sector in the Netherlands. Most of the sorption market at this time comprises direct-fired absorption chillers, or hot water or steam absorption chillers indirectly driven by direct-fired boilers. Throughout the report, this category of absorption chillers is referred to generically as 'direct-fired'. In addition, this report covers absorption (reversible) heat pumps, absorption heat transformers, compression-absorption heat pumps, and adsorption chillers and heat pumps. Adsorption systems together with desiccant systems are also addressed. Chapter 4, Factors Affecting the Market, considers economic, environmental and policy issues. The geographical make-up of the world sorption market is then reviewed, followed by a number of practical operating and control considerations. These include vacuum requirements, crystallisation, corrosion, maintenance, health and

  15. Summary of [alpha]-FLOW, a general purpose three-dimensional fluid analyzing system. Han[prime]yo sanjigen ryutai kaiseki system [alpha]-FLOW no gaiyo

    Energy Technology Data Exchange (ETDEWEB)

    Koike, H [Fuji Research Institute Corporation, Tokyo (Japan)

    1992-08-01

    The [alpha]-FLOW is a three-dimensional fluid analyzing software developed from cooperations among research institutes of private business companies and universities in Japan under the assistance from the Ministry of International Trade and Industry. This paper describes its summary and features. The system is a discrete system utilizing a supercomputer and a work station. The analysis modules incorporated in the system include those for non-compressive fluid analysis, compressive fluid analysis, analysis of non-compressive fluid including free surface, analysis of flows including combustion and chemical reactions, substance migration analysis, and heat transfer analysis. It has a feature that even non-specialists can analyze fluids easily as a result of the development of an expert system to support the numerical analysis. Development of the input data preparing system enables to utilize the work station to process from shape modeling to grid generation, and from inputting analyzing condition data to calculating the flows and outputting the calculation result, all in dialogue modes. An open architecture was adopted. 27 refs., 7 figs., 10 tabs.

  16. Hybrid compression/absorption type heat utilization system (eco-energy city project)

    Energy Technology Data Exchange (ETDEWEB)

    Karimata, T.; Susami, S.; Ogawa, Y. [Research and Development Dept., EBARA Corp., Kanagawa pref. (Japan)

    1999-07-01

    This research is intended to develop a 'hybrid compression/absorption type heat utilization system' by combining an absorption process with a compression process in one circulation cycle. This system can produce chilling heat for ice thermal storage by utilizing low-temperature waste heat (lower than 100 C) which is impossible to treat with a conventional absorption chiller. It means that this system will be able to solve the problem of a timing mismatch between waste heat and heat demand. The working fluid used in this proposed system should be suitable for producing ice, be safe, and not damage the ozone layer. In this project, new working fluids were searched as substitutes for the existing H{sub 2}O/LiBr or NH{sub 3}/H{sub 2}O. The interim results of this project in 1997, a testing unit using NH{sub 3}/H{sub 2}O was built for demonstration of the system and evaluation of its characteristics, and R134a/E181 was found to be one of the good working fluid for this system. The COP (ratio of energy of ice produced to electric power provided) of this system using R134a/E181 is expected to achieve 5.5 by computer simulation. The testing unit with this working fluid was built recently and prepared for the tests to confirm the result of the simulation. (orig.)

  17. Thermodynamic performance analysis of gas-fired air-cooled adiabatic absorption refrigeration systems

    International Nuclear Information System (INIS)

    Wang, L.; Chen, G.M.; Wang, Q.; Zhong, M.

    2007-01-01

    In China, the application of small size gas-fired air-cooled absorption refrigeration systems as an alternative for electric compression air conditioning systems has shown broad prospects due to occurrence of electricity peak demand in Chinese big cities and lack of water resources. However, for conventional air-cooled absorption refrigeration systems, it is difficult to enhance the heat and mass transfer process in the falling film absorber, and may cause problems, for example, remarkable increase of pressure, temperature and concentration in the generators, risk of crystallization, acceleration of corrosion, degradation of performance, and so on. This paper presents a gas-fired air-cooled adiabatic absorption refrigeration system using lithium bromide-water solutions as its working fluid, which is designed with a cooling capacity of 16 kW under standard conditions. The system has two new features of waste heat recovery of condensed water from generator and an adiabatic absorber with an air cooler. Performance simulation and characteristic analysis are crucial for the optimal control and reliability of operation in extremely hot climates. A methodology is presented to simulate thermodynamic performance of the system. The influences of outdoor air temperature on operation performances of the system are investigated

  18. Use of a parallel artificial membrane system to evaluate passive absorption and elimination in small fish.

    Science.gov (United States)

    Kwon, Jung-Hwan; Katz, Lynn E; Liljestrand, Howard M

    2006-12-01

    A parallel artificial lipid membrane system was developed to mimic passive mass transfer of hydrophobic organic chemicals in fish. In this physical model system, a membrane filter-supported lipid bilayer separates two aqueous phases that represent the external and internal aqueous environments of fish. To predict bioconcentration kinetics in small fish with this system, literature absorption and elimination rates were analyzed with an allometric diffusion model to quantify the mass transfer resistances in the aqueous and lipid phases of fish. The effect of the aqueous phase mass transfer resistance was controlled by adjusting stirring intensity to mimic bioconcentration rates in small fish. Twenty-three simple aromatic hydrocarbons were chosen as model compounds for purposes of evaluation. For most of the selected chemicals, literature absorption/elimination rates fall into the range predicted from measured membrane permeabilities and elimination rates of the selected chemicals determined by the diffusion model system.

  19. Design of absorption system water-ammonia by using solar radiation as thermal source

    Energy Technology Data Exchange (ETDEWEB)

    Cavalcanti, Eduardo J. Cidade; Souza, Luiz Guilherme Meira [Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN (Brazil). Centro de Tecnlogia. Dept. de Engenharia Mecanica], E-mails: educanti@gmail.com, lguilherme@dem.ufrn.br

    2010-07-01

    An absorption refrigeration system with the single effect of par ammonia water with 1.758 kW (1 / 2 RT) cooling capacity was designed. The system was operating under conditions of 5 degree C evaporation and 45 degree C condensation temperature. The absorption system has a heat exchanger to improve performance. The heat source is the cylinder parabolic solar concentrator (CPC). The design of the concentrator was estimated based on experimental data of the pilot plant built in the Solar Energy Laboratory, Federal University of Rio Grande do Norte. The thermodynamic model with heat and mass transfer was made to the project areas of heat exchange (absorber) and consequent construction of the system. The rectifying column was modeling assuming that liquid is in equilibrium with the vapor state in all plate. The results should show the dimensions of the compact and allows a future assessment of the operational cost. (author)

  20. Two-dimensional atom localization via probe absorption in a four-level atomic system

    International Nuclear Information System (INIS)

    Wang Zhi-Ping; Ge Qiang; Ruan Yu-Hua; Yu Ben-Li

    2013-01-01

    We have investigated the two-dimensional (2D) atom localization via probe absorption in a coherently driven four-level atomic system by means of a radio-frequency field driving a hyperfine transition. It is found that the detecting probability and precision of 2D atom localization can be significantly improved via adjusting the system parameters. As a result, our scheme may be helpful in laser cooling or the atom nano-lithography via atom localization

  1. Designing the lithium bromide air conditioning absorption system for a bus

    International Nuclear Information System (INIS)

    Yusoff Ali; Kamaruzzaman Sopian; Hariadi

    2006-01-01

    A system of air-conditioning using Lithium Bromide absorption system is used as an alternative refrigerant that will not pollute the atmosphere. Lithium Bromide is a chemical salt soluble in water. There is a big difference between vapour compression system and LiBr 2 absorption system. The absorption air conditioning system is made of a generator, a condenser, an evaporator and an absorber with necessary pumps and piping. When LiBr 2 solution is heated under low pressure, water will evaporate first, while LiBr 2 will remain in the solution and will become more concentrated. The water is the refrigerant in this system. The generator, where the water is vapourised, is heated using an electric heater or solar energy. The LiBr 2 weak solution under low pressure in the generator is heated and the water evaporate into vapour. The vapour produced is then cooled in the condenser and then expanded into the evaporator. The refrigerant (water) in evaporator change phase from liquid to vapour by absorbing heat from cooling water, which flow in the coil in the evaporator. The chilled water obtained is then pumped into the fan coil, which will be used in conditioning the passenger area of the bus. The water vapour from the evaporator is absorbed into LiBr 2 solution in the absorber, forming a weak solution of LiBr 2 . the weak solution from the absorber is then pumped back to the generator to regenerate. The absorption system does not use compressor, but requires pumps that need lower input power compared to that of a compressor. The system is considered as a new application for the bus. This will have great potential and will be environmentally friendly. The model in this study will be used for calculation of the cooling load for the bus

  2. ORIGINS OF ABSORPTION SYSTEMS OF CLASSICAL NOVA V2659 CYG (NOVA CYG 2014)

    Energy Technology Data Exchange (ETDEWEB)

    Arai, A.; Kawakita, H. [Koyama Astronomical Observatory, Kyoto Sangyo University, Motoyama, Kamigamo, Kita-ku, Kyoto 603-8555 (Japan); Shinnaka, Y. [National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan); Tajitsu, A., E-mail: arai6a@cc.kyoto-su.ac.jp [Subaru Telescope, National Astronomical Observatory of Japan, 650 North A’ohoku Place, Hilo, Hawaii 96720 (United States)

    2016-10-10

    We report on high-dispersion spectroscopy results of a classical nova V2659 Cyg (Nova Cyg 2014) that are taken 33.05 days after the V -band maximum. The spectrum shows two distinct blueshifted absorption systems originating from H i, Fe ii, Ca ii, etc. The radial velocities of the absorption systems are −620 km s{sup −1}, and −1100 to −1500 km s{sup −1}. The higher velocity component corresponds to the P-Cygni absorption features frequently observed in low-resolution spectra. Much larger numbers of absorption lines are identified at the lower velocity. These mainly originate from neutral or singly ionized Fe-peak elements (Fe i, Ti ii, Cr ii, etc.). Based on the results of our spectroscopic observations, we discuss the structure of the ejecta of V2659 Cyg. We conclude that the low- and high-velocity components are likely to be produced by the outflow wind and the ballistic nova ejecta, respectively.

  3. Spectral control of an alexandrite laser for an airborne water-vapor differential absorption lidar system

    Science.gov (United States)

    Ponsardin, Patrick; Grossmann, Benoist E.; Browell, Edward V.

    1994-01-01

    A narrow-linewidth pulsed alexandrite laser has been greatly modified for improved spectral stability in an aircraft environment, and its operation has been evaluated in the laboratory for making water-vapor differential absorption lidar measurements. An alignment technique is described to achieve the optimum free spectral range ratio for the two etalons inserted in the alexandrite laser cavity, and the sensitivity of this ratio is analyzed. This technique drastically decreases the occurrence of mode hopping, which is commonly observed in a tunable, two-intracavity-etalon laser system. High spectral purity (greater than 99.85%) at 730 nm is demonstrated by the use of a water-vapor absorption line as a notch filter. The effective cross sections of 760-nm oxygen and 730-nm water-vapor absorption lines are measured at different pressures by using this laser, which has a finite linewidth of 0.02 cm(exp -1) (FWHM). It is found that for water-vapor absorption linewidths greater than 0.04 cm(exp -1) (HWHM), or for altitudes below 10 km, the laser line can be considered monochromatic because the measured effective absorption cross section is within 1% of the calculated monochromatic cross section. An analysis of the environmental sensitivity of the two intracavity etalons is presented, and a closed-loop computer control for active stabilization of the two intracavity etalons in the alexandrite laser is described. Using a water-vapor absorption line as a wavelength reference, we measure a long-term frequency drift (approximately 1.5 h) of less than 0.7 pm in the laboratory.

  4. Graphical expression of thermodynamic characteristics of absorption process in ammonia-water system

    Directory of Open Access Journals (Sweden)

    Fortelný Zdeněk

    2012-04-01

    Full Text Available The adiabatic sorption is very interesting phenomenon that occurs when vapor of refrigerant is in contact with unsaturated liquid absorbent-refrigerant mixture and exchange of heat is forbid between the system and an environment. This contribution introduces new auxiliary lines that enable correct position determination of the adiabatic sorption process in the p-T-x diagram of ammoniawater system. The presented auxiliary lines were obtained from common functions for fast calculation of water-ammonia system properties. Absorption cycles designers often utilize p-t-x diagrams of working mixtures for first suggestion of new absorption cycles. The p-t-x diagrams enable fast correct determination of saturate states of liquid (and gaseous mixtures of refrigerants and absorbents. The working mixture isn’t only at saturated state during a real working cycle. If we know pressure and temperature of an unsaturated mixture, exact position determination is possible in the p-t-x diagrams too.

  5. [Signal analysis and spectrum distortion correction for tunable diode laser absorption spectroscopy system].

    Science.gov (United States)

    Bao, Wei-Yi; Zhu, Yong; Chen, Jun; Chen, Jun-Qing; Liang, Bo

    2011-04-01

    In the present paper, the signal of a tunable diode laser absorption spectroscopy (TDLAS) trace gas sensing system, which has a wavelength modulation with a wide range of modulation amplitudes, is studied based on Fourier analysis method. Theory explanation of spectrum distortion induced by laser intensity amplitude modulation is given. In order to rectify the spectrum distortion, a method of synchronous amplitude modulation suppression by a variable optical attenuator is proposed. To validate the method, an experimental setup is designed. Absorption spectrum measurement experiments on CO2 gas were carried out. The results show that the residual laser intensity modulation amplitude of the experimental system is reduced to -0.1% of its original value and the spectrum distortion improvement is 92% with the synchronous amplitude modulation suppression. The modulation amplitude of laser intensity can be effectively reduced and the spectrum distortion can be well corrected by using the given correction method and system. By using a variable optical attenuator in the TDLAS (tunable diode laser absorption spectroscopy) system, the dynamic range requirements of photoelectric detector, digital to analog converter, filters and other aspects of the TDLAS system are reduced. This spectrum distortion correction method can be used for online trace gas analyzing in process industry.

  6. A thermodynamic evaluation on high pressure condenser of double effect absorption refrigeration system

    International Nuclear Information System (INIS)

    Yılmaz, İbrahim Halil; Saka, Kenan; Kaynakli, Omer

    2016-01-01

    One of the parameters affecting the COP of the absorption system can be considered as the thermal balance between the high pressure condenser (HPC) and the low pressure generator (LPG) since heat rejected from the HPC is utilized as an energy source by the LPG. Condensation of the water vapor in the HPC depends on the heat removal via the LPG. This circumstance is significant for making an appropriate design and a controllable system with high performance in practical applications. For this reason, a thermodynamic analysis for the HPC of a double effect series flow water/lithium bromide absorption refrigeration system was emphasized in this study. A simulation was developed to investigate the energy transfer between the HPC and LPG. The results show that the proper designation of the HPC temperature improves the COP and ECOP due its significant impact, and its value necessarily has to be higher than the outlet temperature of the LPG based on the operating scheme. Furthermore, the COP and ECOP of the absorption system can be raised in the range of 9.72–35.09% in case of 2 °C-temperature increment in the HPC under the described conditions to be applied. - Highlights: • Thermal balance in HPC/LPG unit of a double effect absorption system was studied. • A simulation program was developed and its outputs were validated. • A parametric study was conducted for a wide range of component temperatures. • Proper designation of the HPC temperature improves the COP and ECOP. • The system performance raised 9.72–35.09% by controlling the HPC temperature.

  7. Cavity ring-down spectroscopy (CRDS) system for measuring atmospheric mercury using differential absorption

    Science.gov (United States)

    Pierce, A.; Obrist, D.; Moosmuller, H.; Moore, C.

    2012-04-01

    Atmospheric elemental mercury (Hg0) is a globally pervasive element that can be transported and deposited to remote ecosystems where it poses — particularly in its methylated form — harm to many organisms including humans. Current techniques for measurement of atmospheric Hg0 require several liters of sample air and several minutes for each analysis. Fast-response (i.e., 1 second or faster) measurements would improve our ability to understand and track chemical cycling of mercury in the atmosphere, including high frequency Hg0 fluctuations, sources and sinks, and chemical transformation processes. We present theory, design, challenges, and current results of our new prototype sensor based on cavity ring-down spectroscopy (CRDS) for fast-response measurement of Hg0 mass concentrations. CRDS is a direct absorption technique that implements path-lengths of multiple kilometers in a compact absorption cell using high-reflectivity mirrors, thereby improving sensitivity and reducing sample volume compared to conventional absorption spectroscopy. Our sensor includes a frequency-doubled, dye-laser emitting laser pulses tunable from 215 to 280 nm, pumped by a Q-switched, frequency tripled Nd:YAG laser with a pulse repetition rate of 50 Hz. We present how we successfully perform automated wavelength locking and stabilization of the laser to the peak Hg0 absorption line at 253.65 nm using an external isotopically-enriched mercury (202Hg0) cell. An emphasis of this presentation will be on the implementation of differential absorption measurement whereby measurements are alternated between the peak Hg0 absorption wavelength and a nearby wavelength "off" the absorption line. This can be achieved using a piezo electric tuning element that allows for pulse-by-pulse tuning and detuning of the laser "online" and "offline" of the Hg absorption line, and thereby allows for continuous correction of baseline extinction losses. Unexpected challenges with this approach included

  8. Open absorption system for cooling and air conditioning using membrane contactors - Final report

    Energy Technology Data Exchange (ETDEWEB)

    Conde-Petit, M. [M. Conde Engineering, Zuerich (Switzerland); Weber, R.; Dorer, V. [Swiss Federal Laboratories for Materials Testing and Research (EMPA), Duebendorf (Switzerland)

    2008-07-01

    Air conditioning systems based upon the open absorption principle, essentially an absorption device operating at atmospheric pressure, have been proposed and investigated at many instances in the past eighty years. Their potential for improving energy efficiency is clearly recognized in the earliest research reports. By the mid 1950ies, solar thermal energy was being applied to drive open absorption-based air conditioning systems. For several reasons, however, the open absorption technology was not mature enough to take place in the mainstream. In the past two decades, vigorous efforts have been undertaken to reverse this situation, but success continued to elude, despite the fact that the main problems, such as corrosion, aerosols in the supply air, etc., have been identified. This report details the work and the main results from the MemProDEC Project. In this project innovative solutions were proposed, and successfully investigated, for the corrosion problem and the improvement of efficiency of the absorption process, in particular a new method to cool a very compact absorber. The practically uniform flow distribution for all three streams in the absorber (air, water and desiccant) warrants the contact of the air to be dehumidified with the desiccant over the whole surface of exchange (across a porous membrane). This, together with the cooling with water in counter flow to the air, are the key factors for the excellent effectiveness of the absorber. As the results show, the dehydration effectiveness of the prototype absorber is up to 150 % higher than that previously obtained by others. The solutions developed for compactness and modularity represent an important step in the way to flexible manufacturing, i.e. using a single element size to assemble autonomous air handling units of various nominal capacities. And although the manufacturing methods of the individual elements require improvement, namely by avoiding adhesive bonding, the choice of materials and the

  9. Energy and exergy analysis of a double effect absorption refrigeration system based on different heat sources

    International Nuclear Information System (INIS)

    Kaynakli, Omer; Saka, Kenan; Kaynakli, Faruk

    2015-01-01

    Highlights: • Energy and exergy analysis was performed on double effect series flow absorption refrigeration system. • The refrigeration system runs on various heat sources such as hot water, hot air and steam. • A comparative analysis was carried out on these heat sources in terms of exergy destruction and mass flow rate of heat source. • The effect of heat sources on the exergy destruction of high pressure generator was investigated. - Abstract: Absorption refrigeration systems are environmental friendly since they can utilize industrial waste heat and/or solar energy. In terms of heat source of the systems, researchers prefer one type heat source usually such as hot water or steam. Some studies can be free from environment. In this study, energy and exergy analysis is performed on a double effect series flow absorption refrigeration system with water/lithium bromide as working fluid pair. The refrigeration system runs on various heat sources such as hot water, hot air and steam via High Pressure Generator (HPG) because of hot water/steam and hot air are the most common available heat source for absorption applications but the first law of thermodynamics may not be sufficient analyze the absorption refrigeration system and to show the difference of utilize for different type heat source. On the other hand operation temperatures of the overall system and its components have a major effect on their performance and functionality. In this regard, a parametric study conducted here to investigate this effect on heat capacity and exergy destruction of the HPG, coefficient of performance (COP) of the system, and mass flow rate of heat sources. Also, a comparative analysis is carried out on several heat sources (e.g. hot water, hot air and steam) in terms of exergy destruction and mass flow rate of heat source. From the analyses it is observed that exergy destruction of the HPG increases at higher temperature of the heat sources, condenser and absorber, and lower

  10. Certification of model spectrometric alpha sources (MSAS) and problems of the MSAS system improvement

    International Nuclear Information System (INIS)

    Belyatskij, A.F.; Gejdel'man, A.M.; Egorov, Yu.S.; Nedovesov, V.G.; Chechev, V.P.

    1984-01-01

    Results of certification of standard spectrometric alpha sources (SSAS) of industrial production are presented: methods for certification by main radiation physical parameters: proper halfwidth of α-lines, activity of radionuclides in the source, energies of α-particle emitting sources and relative intensity of different energy α-particle groups - are analysed. The advantage for the SSAS system improvement - a set of model measures for α-radiation, a collection of interconnected data units on physical, engineering and design characteristics of SSAS, methods for their obtaining and determination, on instruments used, is considered

  11. Determining CDOM Absorption Spectra in Diverse Aquatic Environments Using a Multiple Pathlength, Liquid Core Waveguide System

    Science.gov (United States)

    Miller, Richard L.; Belz, Mathias; DelCastillo, Carlos; Trzaska, Rick

    2001-01-01

    We evaluated the accuracy, sensitivity and precision of a multiple pathlength, liquid core waveguide (MPLCW) system for measuring colored dissolved organic matter (CDOM) absorption in the UV-visible spectral range (370-700 nm). The MPLCW has four optical paths (2.0, 9.8, 49.3, and 204 cm) coupled to a single Teflon AF sample cell. Water samples were obtained from inland, coastal and ocean waters ranging in salinity from 0 to 36 PSU. Reference solutions for the MPLCW were made having a refractive index of the sample. CDOM absorption coefficients, aCDOM, and the slope of the log-linearized absorption spectra, S, were compared with values obtained using a dual-beam spectrophotometer. Absorption of phenol red secondary standards measured by the MPLCW at 558 nm were highly correlated with spectrophotometer values and showed a linear response across all four pathlengths. Values of aCDOM measured using the MPLCW were virtually identical to spectrophotometer values over a wide range of concentrations. The dynamic range of aCDOM for MPLCW measurements was 0.002 - 231.5 m-1. At low CDOM concentrations spectrophotometric aCDOM were slightly greater than MPLCW values and showed larger fluctuations at longer wavelengths due to limitations in instrument precision. In contrast, MPLCW spectra followed an exponential to 600 nm for all samples.

  12. Effect of resin system on the mechanical properties and water absorption of kenaf fibre reinforced laminates

    International Nuclear Information System (INIS)

    Rassmann, S.; Paskaramoorthy, R.; Reid, R.G.

    2011-01-01

    The objective of this study is to compare the mechanical and water absorption properties of kenaf (Hibiscus cannabinus L.) fibre reinforced laminates made of three different resin systems. The use of different resin systems is considered so that potentially complex and expensive fibre treatments are avoided. The resin systems used include a polyester, a vinyl ester and an epoxy. Laminates of 15%, 22.5% and 30% fibre volume fraction were manufactured by resin transfer moulding. The laminates were tested for strength and modulus under tensile and flexural loading. Additionally, tests were carried out on laminates to determine the impact energy, impact strength and water absorption. The results revealed that properties were affected in markedly different ways by the resin system and the fibre volume fraction. Polyester laminates showed good modulus and impact properties, epoxy laminates displayed good strength values and vinyl ester laminates exhibited good water absorption characteristics. Scanning electron microscope studies show that epoxy laminates fail by fibre fracture, polyester laminates by fibre pull-out and vinyl ester laminates by a combination of the two. A comparison between kenaf and glass laminates revealed that the specific tensile and flexural moduli of both laminates are comparable at the volume fraction of 15%. However, glass laminates have much better specific properties than the kenaf laminates at high fibre volume fractions for all three resins used.

  13. Tunable Absorption System based on magnetorheological elastomers and Halbach array: design and testing

    Energy Technology Data Exchange (ETDEWEB)

    Bocian, Mirosław; Kaleta, Jerzy; Lewandowski, Daniel, E-mail: daniel.lewandowski@pwr.edu.pl; Przybylski, Michał

    2017-08-01

    Highlights: • Construction of a Tunable Absorption System incorporating MRE has been done. • For system control by magnetic field a double circular Halbach array has been used. • Significant changes of the TSAs natural frequency and damping has been obtained. - Abstract: In this paper, the systematic design, construction and testing of a Tunable Absorption System (TAS) incorporating magnetorheological elastomer (MRE) has been investigated. The TAS has been designed for energy absorption and mitigation of vibratory motions from an impact excitation. The main advantage of the designed TAS is that it has the ability to change and adapt to working conditions. Tunability can be realised through a change in the magnetic field caused by the change of an internal arrangement of permanent magnets within a double dipolar circular Halbach array. To show the capabilities of the tested system, experiments based on an impulse excitation have been performed. Significant changes of the TASs natural frequency and damping characteristics have been obtained. By incorporating magnetic tunability within the TAS a significant qualitative and quantitative change in the devices mechanical properties and performance were obtained.

  14. The importance of the ammonia purification process in ammonia-water absorption systems

    International Nuclear Information System (INIS)

    Fernandez-Seara, Jose; Sieres, Jaime

    2006-01-01

    Practical experience in working with ammonia-water absorption systems shows that the ammonia purification process is a crucial issue in order to obtain an efficient and reliable system. In this paper, the detrimental effects of the residual water content in the vapour refrigerant are described and quantified based on the system design variables that determine the effectiveness of the purification process. The study has been performed considering a single stage system with a distillation column with complete condensation. The ammonia purification effectiveness of the column is analysed in terms of the efficiencies in the stripping and rectifying sections and the reflux ratio. By varying the efficiencies from 0 to 1, systems with neither the rectifying nor stripping section, with either the rectifying or stripping section, or with both sections can be considered. The impact of the ammonia purification process on the absorption system performance is studied based on the column efficiencies and reflux ratio; and its effects on refrigerant concentration, system COP, system pressures and main system mass flow rates and concentrations are analysed. When the highest efficiency rectifying sections are used a combination of generation temperature and reflux ratio which leads to optimum COP values is found. The analysis covers different operating conditions with air and water cooled systems from refrigeration to air conditioning applications by changing the evaporation temperature. The importance of rectification in each kind of application is evaluated

  15. Development of the prototype data management system of the solar H-alpha full disk observation

    Science.gov (United States)

    Wei, Ka-Ning; Zhao, Shi-Qing; Li, Qiong-Ying; Chen, Dong

    2004-06-01

    The Solar Chromospheric Telescope in Yunnan Observatory generates about 2G bytes fits format data per day. Huge amounts of data will bring inconvenience for people to use. Hence, data searching and sharing are important at present. Data searching, on-line browsing, remote accesses and download are developed with a prototype data management system of the solar H-alpha full disk observation, and improved by the working flow technology. Based on Windows XP operating system and MySQL data management system, a prototype system of browse/server model is developed by JAVA and JSP. Data compression, searching, browsing, deletion need authority and download in real-time have been achieved.

  16. Differential Optical-absorption Spectroscopy (doas) System For Urban Atmospheric-pollution Monitoring

    OpenAIRE

    Edner, H; Ragnarson, P; Spannare, S; Svanberg, Sune

    1993-01-01

    We describe a fully computer-controlled differential optical absorption spectroscopy system for atmospheric air pollution monitoring. A receiving optical telescope can sequentially tune in to light beams from a number of distant high-pressure Xe lamp light sources to cover the area of a medium-sized city. A beam-finding servosystem and automatic gain control permit unattended long-time monitoring. Using an astronomical code, we can also search and track celestial sources. Selected wavelength ...

  17. Connecting the Interstellar Gas and Dust Properties in Distant Galaxies Using Quasar Absorption Systems

    Science.gov (United States)

    Aller, Monique C.; Dwek, Eliahu; Kulkarni, Varsha P.; York, Donald G.; Welty, Daniel E.; Vladilo, Giovanni; Som, Debopam; Lackey, Kyle; Dwek, Eli; Beiranvand, Nassim; hide

    2016-01-01

    Gas and dust grains are fundamental components of the interstellar medium and significantly impact many of the physical processes driving galaxy evolution, such as star-formation, and the heating, cooling, and ionization of the interstellar material. Quasar absorption systems (QASs), which trace intervening galaxies along the sightlines to luminous quasars, provide a valuable tool to directly study the properties of the interstellar gas and dust in distant, normal galaxies. We have established the presence of silicate dust grains in at least some gas-rich QASs, and find that they exist at higher optical depths than expected for diffuse gas in the Milky Way. Differences in the absorption feature shapes additionally suggest variations in the silicate dust grain properties, such as in the level of grain crystallinity, from system-to-system. We present results from a study of the gas and dust properties of QASs with adequate archival IR data to probe the silicate dust grain properties. We discuss our measurements of the strengths of the 10 and 18 micron silicate dust absorption features in the QASs, and constraints on the grain properties (e.g., composition, shape, crystallinity) based on fitted silicate profile templates. We investigate correlations between silicate dust abundance, reddening, and gas metallicity, which will yield valuable insights into the history of star formation and chemical enrichment in galaxies.

  18. Simultaneous multi-element atomic absorption system using photodiode array detector

    International Nuclear Information System (INIS)

    Tong, S.L.; Chin, K.S.

    1994-01-01

    A photodiode array (PDA) detector-multichannel analyser (MCA) system has been coupled to a flame and a graphite furnace atomiser and tested for simultaneous multielement atomic absorption analysis. Multielement hollow cathode lamps (HCL) are used as light source. Spectral lines are dispersed through a spectrograph with triple gratings and detected by a 25.4 mm PDA detector consisting of 1024 elements. The optical MCA system is capable of recording multiple spectra spanned by the spectrograph/PDA. The transmitted intensity spectra obtained for the standard and analyte solutions during flame or graphite furnace atomisation are converted to absorbance spectra using the MCA software provided. Results from the comparison studies show that the linear range and sensitivities for Ni-Co-Fe and Cu-Cr obtained from the simultaneous measurements are within the same order of magnitudes as those from conventional single element determinations using photomultiplier tube detection. The study also shows that non-atomic absorption can be readily corrected by a two-line method where non-atomic absorption lines can be chosen from the spectra recorded simultaneously. The proposed system has been evaluated for the determination of trace elements using NBS standard reference water SRM 1643b

  19. Triple-effect absorption refrigeration system with double-condenser coupling

    Science.gov (United States)

    DeVault, Robert C.; Biermann, Wendell J.

    1993-01-01

    A triple effect absorption refrigeration system is provided with a double-condenser coupling and a parallel or series circuit for feeding the refrigerant-containing absorbent solution through the high, medium, and low temperature generators utilized in the triple-effect system. The high temperature condenser receiving vaporous refrigerant from the high temperature generator is double coupled to both the medium temperature generator and the low temperature generator to enhance the internal recovery of heat within the system and thereby increase the thermal efficiency thereof.

  20. Evaluation of trigeneration system using microturbine, ammonia-water absorption chiller, and a heat recovery boiler

    Energy Technology Data Exchange (ETDEWEB)

    Preter, Felipe C.; Rocha, Marcelo S.; Simoes-Moreira, Jose Roberto [SISEA - Alternative Energy Systems Lab. Dept. of Mechanical Engineering. University of Sao Paulo (EP/USP), SP (Brazil)], e-mails: felipe.preter@poli.usp.br, msrocha@poli.usp.br, jrsimoes@usp.br; Andreos, Ronaldo [COMGAS - Companhia de Gas de Sao Paulo, SP (Brazil)], e-mail: randreos@comgas.com.br

    2010-07-01

    In this work, a CCHP or tri generation system has been projected, mounted, and tested in laboratory, combining a microturbine for power generation, a heat recovery boiler for hot water production, and an ammonia water absorption chiller for chilled water production. The project was motivated by the large practical applications of this kind of energy recovery system in commerce, and industry, and, in general, more than 85% of the energy source is used as power, hot water, and cold water. In the first part, the trigeneration system theoretical model is detailed, and in the second part, experimental results are presented for different operation conditions. (author)

  1. Trigeneration System Based on Municipal Waste Gasification, Fuel Cell and an Absorption Chiller

    DEFF Research Database (Denmark)

    Katsaros, Giannis; Nguyen, Tuong-Van; Rokni, Masoud

    2016-01-01

    of a specific building is also investigated and the system can fully meet the electricity and cooling demands, whereas the heat needs can be satisfied only up to 55%. Moreover, assuming 20 years of operation, the payback period is 4.3 years and the net present value exceeds 5 MEUR.......The present work focuses on the design of a novel tri-generation system based on municipal solid wastes gasification, solid oxide fuel cell and an ammonia-water absorption chiller. Trigeneration systems can be implemented in buildings such as hospitals, where there is a continuous and large demand...

  2. The Mean Metal-line Absorption Spectrum of Damped Ly α Systems in BOSS

    Energy Technology Data Exchange (ETDEWEB)

    Mas-Ribas, Lluís [Institute of Theoretical Astrophysics, University of Oslo, Postboks 1029, NO-0315 Oslo (Norway); Miralda-Escudé, Jordi; Pérez-Ràfols, Ignasi; Arinyo-i-Prats, Andreu [Institut de Ciències del Cosmos, Universitat de Barcelona (UB-IEEC), Barcelona E-08028, Catalonia (Spain); Noterdaeme, Pasquier; Petitjean, Patrick [Institut d’Astrophysique de Paris, UPMC and CNRS, UMR7095 98bis Boulevard Arago, F-75014—Paris (France); Schneider, Donald P. [Department of Astronomy and Astrophysics, The Pennsylvania State University, University Park, PA 16802 (United States); York, Donald G. [Department of Astronomy and Astrophysics and the Enrico Fermi Institute, University of Chicago, 5640 South Ellis Avenue, Chicago, IL 60637 (United States); Ge, Jian, E-mail: l.m.ribas@astro.uio.no [Department of Astronomy, University of Florida, Bryant Space Science Center, Gainesville, FL 32611-2055 (United States)

    2017-09-01

    We study the mean absorption spectrum of the Damped Ly α (DLA) population at z ∼ 2.6 by stacking normalized, rest-frame-shifted spectra of ∼27,000 DLA systems from the DR12 of the Baryon Oscillation Spectroscopic Survey (BOSS)/SDSS-III. We measure the equivalent widths of 50 individual metal absorption lines in five intervals of DLA hydrogen column density, five intervals of DLA redshift, and overall mean equivalent widths for an additional 13 absorption features from groups of strongly blended lines. The mean equivalent width of low-ionization lines increases with N {sub H} {sub i}, whereas for high-ionization lines the increase is much weaker. The mean metal line equivalent widths decrease by a factor ∼1.1–1.5 from z ∼ 2.1 to z ∼ 3.5, with small or no differences between low- and high-ionization species. We develop a theoretical model, inspired by the presence of multiple absorption components observed in high-resolution spectra, to infer mean metal column densities from the equivalent widths of partially saturated metal lines. We apply this model to 14 low-ionization species and to Al iii, S iii, Si iii, C iv, Si iv, N v, and O vi. We use an approximate derivation for separating the equivalent width contributions of several lines to blended absorption features, and infer mean equivalent widths and column densities from lines of the additional species N i, Zn ii, C ii*, Fe iii, and S iv. Several of these mean column densities of metal lines in DLAs are obtained for the first time; their values generally agree with measurements of individual DLAs from high-resolution, high signal-to-noise ratio spectra when they are available.

  3. Experimental assessment of an absorption cooling system operating with the ammonia/lithium nitrate mixture

    International Nuclear Information System (INIS)

    Hernández-Magallanes, J.A.; Domínguez-Inzunza, L.A.; Gutiérrez-Urueta, G.; Soto, P.; Jiménez, C.; Rivera, W.

    2014-01-01

    This paper reports the experimental results of a single effect absorption cooling system of 3 kW of nominal cooling capacity operating with ammonia–lithium nitrate solution. The system was designed and built in the Instituto de Energías Renovables of the Universidad Nacional Autónoma de México and can be used for food conservation or air conditioning. The absorber and generator are falling film heat exchangers. The condenser, evaporator and solution heat exchanger are compact plate heat exchangers. The heat was supplied to the generator at temperatures between 85 °C and 105 °C, while the cooling water temperatures to remove the heat produced during the condensation and absorption varied between 18 °C and 36 °C. The results showed that the system can produce up to 2.7 kW of cooling capacity at heating water temperatures of 95 °C and can achieve evaporator temperatures as low as 1 °C. The experimental coefficients of performance varied between 0.45 and 0.70. Because of the developed system do not need a rectifier and reasonable good coefficients of performance were achieved, the developed system seems to be a good alternative to be used for food conservation or air conditioning. - Highlights: • An absorption cooling system was developed using NH 3 –LiNO 3 . • The achieved COP (coefficients of performance) are the highest reported for a system using NH 3 –LiNO 3 . • Evaporator temperatures as low as 1 °C were achieved. • COP varied between 0.45 and 0.7. • The developed system seems to be a good alternative for food conservation and air conditioning

  4. Cooling performance and energy saving of a compression-absorption refrigeration system assisted by geothermal energy

    International Nuclear Information System (INIS)

    Kairouani, L.; Nehdi, E.

    2006-01-01

    The objectives of this paper are to develop a novel combined refrigeration system, and to discuss the thermodynamic analysis of the cycle and the feasibility of its practical development. The aim of this work was to study the possibility of using geothermal energy to supply vapour absorption system cascaded with conventional compression system. Three working fluids (R717, R22, and R134a) are selected for the conventional compression system and the ammonia-water pair for the absorption system. The geothermal temperature source in the range 343-349 K supplies a generator operating at 335 K. Results show that the COP of a combined system is significantly higher than that of a single stage refrigeration system. It is found that the COP can be improved by 37-54%, compared with the conventional cycle, under the same operating conditions, that is an evaporation temperature at 263 K and a condensation temperature of 308 K. For industrial refrigeration, the proposed system constitutes an alternative solution for reducing energy consumption and greenhouse gas emissions

  5. Multi-isotopic gamma-ray assay system for alpha-contaminated waste

    International Nuclear Information System (INIS)

    Close, D.A.; Pratt, J.C.; Caldwell, J.T.; Kunz, W.E.; Schultz, F.J.; Haff, K.W.

    1983-01-01

    The capability of an existing segmented gamma-ray system is being expanded for the analysis of alpha-contaminated waste drums. A cursory assay of 114 transuranic waste drums of 208-l capacity has been made. Analysis of these data indicates a detection limit better than 100 nCi/g of waste for 237 Np/ 233 Pa, 239 Pu, 241 Am, 243 Am/ 239 Np, 60 Co, 125 Sb, 134 137 Cs, and 154 Eu. A pending Code of Federal Regulation (10CFR61) stipulates that the nuclear industry quantify not only its transuranic waste, but also certain beta- and gamma-ray-emitting fission products. An assay system based on gamma-ray spectroscopy is the only system that can meet this requirement for the fission products

  6. Effects of local anesthetics on cholinergic agonist binding affinity of central nervous system. cap alpha. -bungarotoxin receptors

    Energy Technology Data Exchange (ETDEWEB)

    Lukas, R.L.; Bennett, E.L.

    1979-12-01

    In general, pharmacological effects of local anesthetics may be attributed to their ability to reversibly block the propagation of nerve and muscle action potentials. At physiologically potent concentrations, local anesthetics (LA) also act as noncompetitive antagonists of the physiological response of post-synaptic nicotinic acetylcholine receptors (nAChR) to cholinergic agonists, and increase agonist binding affinities of nAChR from electric organ. It is postulated that the primary site of LA action on nAChR function is at the receptor-coupled ionophore. Furthermore, LA-nAChR ionophore interactions are thought to accelerate physiological desensitization of nAChR, manifest biochemically as increased affinity of nAChR for agonist. Specific receptors for ..cap alpha..-bungarotoxin (..cap alpha..-Bgt), a potent competitive antagonist at nAChR sites in the periphery, have been detected in rat central nervous system membrane preparations. The affinity of these central ..cap alpha..-Bgt receptors (..cap alpha..-BgtR) for cholinergic agonists is found to increase on exposure to agonist. Nevertheless, on the basis of inconsistent pharmacological and physiological results, uncertainty remains regarding the relationship between ..cap alpha..-BgtR and authentic nAChR in the CNS, despite a wide body of biochemical and histological evidence consistent with their identity. Reasoning that if CNS ..cap alpha..-BgtR are true in nAChR, coupled to functional ion channels, LA might be expected to cause biochemically measurable increases in ..cap alpha..-BgtR affinity for cholinergic agonists, we have undertaken a study of the effects of LA on the ability of acetylcholine (ACh) to inhibit interaction of ..cap alpha..-BgtR with /sup 3/H-labeled ..cap alpha..-Bgt.

  7. NLP model based thermoeconomic optimization of vapor compression–absorption cascaded refrigeration system

    International Nuclear Information System (INIS)

    Jain, Vaibhav; Sachdeva, Gulshan; Kachhwaha, S.S.

    2015-01-01

    Highlights: • It addresses the size and cost estimation of cascaded refrigeration system. • Cascaded system is a promising decarburizing and energy efficient technology. • Second law analysis is carried out with modified Gouy-Stodola equation. • The total annual cost of plant operation is optimized in present work. - Abstract: This paper addresses the size and cost estimation of vapor compression–absorption cascaded refrigeration system (VCACRS) for water chilling application taking R410a and water–LiBr as refrigerants in compression and absorption section respectively which can help the design engineers in manufacturing and experimenting on such kind of systems. The main limitation in the practical implementation of VCACRS is its size and cost which are optimized in the present work by implementing Direct Search Method in non-linear programming (NLP) mathematical model of VCACRS. The main objective of optimization is to minimize the total annual cost of system which comprises of costs of exergy input and capital costs in monetary units. The appropriate set of decision variables (temperature of evaporator, condenser, generator, absorber, cascade condenser, degree of overlap and effectiveness of solution heat exchanger) minimizes the total annual cost of VCACRS by 11.9% with 22.4% reduction in investment cost at the base case whereas the same is reduced by 7.5% with 11.7% reduction in investment cost with reduced rate of interest and increased life span and period of operation. Optimization results show that the more investment cost in later case is well compensated through the performance and operational cost of the system. In the present analysis, optimum cascade condensing temperature is a strong function of period of operation and capital recovery factor. The cascading of compression and absorption systems becomes attractive for lower rate of interest and increase life span and operational period

  8. Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy.

    Directory of Open Access Journals (Sweden)

    Ammar Al-Chalabi

    Full Text Available BACKGROUND: Multiple system atrophy (MSA is a progressive neurodegenerative disorder characterized by parkinsonism, cerebellar ataxia and autonomic dysfunction. Pathogenic mechanisms remain obscure but the neuropathological hallmark is the presence of alpha-synuclein-immunoreactive glial cytoplasmic inclusions. Genetic variants of the alpha-synuclein gene, SNCA, are thus strong candidates for genetic association with MSA. One follow-up to a genome-wide association of Parkinson's disease has identified association of a SNP in SNCA with MSA. METHODOLOGY/FINDINGS: We evaluated 32 SNPs in the SNCA gene in a European population of 239 cases and 617 controls recruited as part of the Neuroprotection and Natural History in Parkinson Plus Syndromes (NNIPPS study. We used 161 independently collected samples for replication. Two SNCA SNPs showed association with MSA: rs3822086 (P = 0.0044, and rs3775444 (P = 0.012, although only the first survived correction for multiple testing. In the MSA-C subgroup the association strengthened despite more than halving the number of cases: rs3822086 P = 0.0024, OR 2.153, (95% CI 1.3-3.6; rs3775444 P = 0.0017, OR 4.386 (95% CI 1.6-11.7. A 7-SNP haplotype incorporating three SNPs either side of rs3822086 strengthened the association with MSA-C further (best haplotype, P = 8.7 x 10(-4. The association with rs3822086 was replicated in the independent samples (P = 0.035. CONCLUSIONS/SIGNIFICANCE: We report a genetic association between MSA and alpha-synuclein which has replicated in independent samples. The strongest association is with the cerebellar subtype of MSA. TRIAL REGISTRATION: ClinicalTrials.gov NCT00211224.

  9. Experimental assessment of an absorption cooling system utilizing a falling film absorber and generator

    International Nuclear Information System (INIS)

    Domínguez-Inzunza, L.A.; Hernández-Magallanes, J.A.; Soto, P.; Jiménez, C.; Gutiérrez-Urueta, G.; Rivera, W.

    2016-01-01

    Highlights: • A new prototype of an absorption cooling system using NH_3/LiNO_3 was developed. • Falling films shell and tubes heat exchangers were used as absorber and generator. • Evaporator temperatures as low as 4 °C were achieved. • The COP varied between 0.27 and 0.62 depending on the system temperatures. • A flow recirculation in the absorber was implemented showing an increase in COP. - Abstract: This study presents the results of the evaluation of an ammonia/lithium nitrate absorption cooling system. The generator and the absorber are shell and tubes falling film heat exchangers while the rest of the components are compact plate heat exchangers. A parametric study was carried out in order to determine the coefficients of performance and cooling capacities at different operating conditions. Also, an analysis was carried out to determine the influence of the absorber solution recirculation on the system performance. The generator temperatures varied between 80 °C and 100 °C, while the cooling water temperatures varied from 20 °C to 34 °C. Cooling capacities up to 4.5 kW and evaporator temperatures as low as 4 °C were achieved with the system. The internal coefficients of performance varied between 0.3 and 0.62 depending on the system operating temperatures. The system also showed good stability and repeatability.

  10. Analysis of a multicomponent gas absorption system with carrier gas coabsorption

    International Nuclear Information System (INIS)

    Merriman, J.R.

    1975-03-01

    Conventional integrated versions of the packed gas absorber design equations do not account for significant coabsorption of the carrier gas along with the dilute transferring species. These equations, as a result, also neglect the relationship between dilute component transfer and carrier gas coabsorption. In the absorption of Kr and Xe from various carrier gases, using CCl 2 F 2 as the process solvent, carrier coabsorption is substantial. Consequently, a design package was developed to deal with multicomponent gas absorption in systems characterized by carrier gas coabsorption. Developed within the general film theory framework, the basic feature of this design approach is a view of dilute component mass-transfer as a conventional diffusive transfer superimposed on a net flux caused by carrier absorption. Other supporting elements of the design package include predictive techniques for various fluid properties, estimating procedures for carrier gas equilibrium constants, and correlations for carrier gas and dilute gas mass-transfer coefficients. When applied to systems using CCl 2 F 2 as the solvent; He, N 2 , air, or Ar as the carrier gas; and Kr or Xe as the dilute gas; the design approach gave good results, even when extended to conditions well beyond those of its development. (U.S.)

  11. Dynamic investigation of the diffusion absorption refrigeration system NH3-H2O-H2

    Directory of Open Access Journals (Sweden)

    Mohamed Izzedine Serge Adjibade

    2017-09-01

    Full Text Available This paper reports on a numerical and experimental study of a diffusion absorption refrigerator. The performance of the system is examined by computer simulation using MATLAB software and Engineering Equations Solver. A dynamic model is developed for each component of the system and solved numerically in order to predict the transient state of the diffusion absorption refrigeration. The experiment set included 0.04 m3 commercial absorption diffusion refrigerator working with the ammonia-water-hydrogen (NH3-H2O-H2 solution. The transient numerical results were validated with the experimental data. The investigations are focused on the dynamic profile of the temperature of each component. The results obtained agree with the experiment; the relative error between numerical and experimental models doesn’t exceed 15% for all temperatures of each component. The increase of the average ambient temperature from 23.04 °C to 32.56 °C causes an increase of the condensation temperature from 29.46 °C to 37.51 °C, and the best evaporation temperature obtained was 3 °C, with an ambient temperature of 23.04 °C. The results show that a minimum starting temperature of 152 °C and 63.8 W electric power are required to initiate the decrease of evaporation temperature.

  12. Space Launch System Base Heating Test: Tunable Diode Laser Absorption Spectroscopy

    Science.gov (United States)

    Parker, Ron; Carr, Zak; MacLean, Mathew; Dufrene, Aaron; Mehta, Manish

    2016-01-01

    This paper describes the Tunable Diode Laser Absorption Spectroscopy (TDLAS) measurement of several water transitions that were interrogated during a hot-fire testing of the Space Launch Systems (SLS) sub-scale vehicle installed in LENS II. The temperature of the recirculating gas flow over the base plate was found to increase with altitude and is consistent with CFD results. It was also observed that the gas above the base plate has significant velocity along the optical path of the sensor at the higher altitudes. The line-by-line analysis of the H2O absorption features must include the effects of the Doppler shift phenomena particularly at high altitude. The TDLAS experimental measurements and the analysis procedure which incorporates the velocity dependent flow will be described.

  13. Using waste heat of ship as energy source for an absorption refrigeration system

    International Nuclear Information System (INIS)

    Salmi, Waltteri; Vanttola, Juha; Elg, Mia; Kuosa, Maunu; Lahdelma, Risto

    2017-01-01

    Highlights: • A steady-state thermodynamic model is developed for absorption refrigeration in a ship. • Operation profile of B.Delta37 bulk carrier is used as an initial data. • Suitability of water-LiBr and ammonia-water working pairs were validated. • Coefficient of performance (COP) was studied in ISO and tropical conditions. • Estimated energy savings were 47 and 95 tons of fuel every year. - Abstract: This work presents a steady-state thermodynamic model for absorption refrigeration cycles with water-LiBr and ammonia-water working pairs for purpose of application on a ship. The coefficient of performance was studied with different generator and evaporator temperatures in ISO and tropical conditions. Absorption refrigeration systems were examined using exhaust gases, jacket water, and scavenge air as energy sources. Optimal generator temperatures for different refrigerant temperatures were found using different waste heat sources and for the absorption cycle itself. Critical temperature values (where the refrigeration power drops to zero) were defined. All of these values were used in order to evaluate the cooling power and energy production possibilities in a bulk carrier. The process data of exhaust gases and cooling water flows in two different climate conditions (ISO and tropical) and operation profiles of a B. Delta37 bulk carrier were used as initial data in the study. With the case ship data, a theoretical potential of saving of 70% of the electricity used in accommodation (AC use) compressor in ISO conditions and 61% in tropical conditions was recognized. Those estimates enable between 47 and 95 tons of annual fuel savings, respectively. Moreover, jacket water heat recovery with a water-LiBr system has the potential to provide 2.2–4.0 times more cooling power than required during sea-time operations in ISO conditions, depending on the main engine load.

  14. Experimental investigation on an ammonia-water-lithium bromide absorption refrigeration system without solution pump

    International Nuclear Information System (INIS)

    Wu Tiehui; Wu Yuyuan; Yu Zhiqiang; Zhao Haichen; Wu Honglin

    2011-01-01

    Highlights: → An absorption refrigeration system with ternary solution of NH 3 -H 2 O-LiBr was set up. → Performance of the NH 3 -H 2 O-LiBr system without solution pump was firstly tested. → Generator pressure in NH 3 -H 2 O-LiBr system was lower than the one in NH 3 -H 2 O system. → The COP of the NH 3 -H 2 O-LiBr system was 51.89% larger than the NH 3 -H 2 O binary system. → The optimum mass fraction of LiBr of about 23% led to the largest COP of 0.401. -- Abstract: Experimental researches were carried out on a novel ammonia-water-lithium bromide ternary solution absorption refrigeration and air-conditioning system without solution pump and distillation equipments. The experiments were conducted by using three kinds of NH 3 -H 2 O binary solution and 17 kinds of ternary solution with difference in mass fraction of NH 3 and LiBr. The experimental results showed that the vapor pressure of the generator in the system would be lower than that of the generator in an ammonia-water absorption system. In above two situations the same ammonia mass fraction and the same solution temperature were kept. The amplitude of vapor pressure decrease of the system generator would be larger with the increase of the mass fraction of LiBr. The maximum amplitude of decrease would be of 50%. With the increase of the mass fraction of LiBr, the coefficient of performance (COP) of the system would be increased initially, and then decreased later when the mass fraction of LiBr exceeded a certain value. This value was about 23% for the solution with ammonia mass fraction of 50% and 55%, and about 30% for the solution with ammonia mass fraction of 60%. Compared with the ammonia-water system, the COP of the ternary solution system with the same mass fraction of ammonia would increase up to 30%. With the ammonia mass fraction of 60% and LiBr mass fraction of 30% applied, the COP of the ternary solution system was increased up to 0.401. It was 51.89% higher than that when binary

  15. Moisture absorption characteristics of the Orbiter thermal protection system and methods used to prevent water ingestion

    Science.gov (United States)

    Schomburg, C.; Dotts, R. L.; Tillian, D. J.

    1983-01-01

    The Space Shuttle Orbiter's silica tile Thermal Protection System (TPS) is beset by the moisture absorption problems inherently associated with low density, highly porous insulation systems. Attention is presently given to the comparative success of methods for the minimization and/or prevention of water ingestion by the TPS tiles, covering the development of water-repellent agents and their tile application techniques, flight test program results, and materials improvements. The use of external films for rewaterproofing of the TPS tiles after each mission have demonstrated marginal to unacceptable performance. By contrast, a tile interior waterproofing agent has shown promise.

  16. Second law comparison of single effect and double effect vapour absorption refrigeration systems

    International Nuclear Information System (INIS)

    Gomri, Rabah

    2009-01-01

    In this paper a comparative study between single effect and double effect absorption refrigeration systems with identical cold output is carried out. Simulation results were used to study the influence of the various operating parameters on the performance coefficient, the thermal loads of the components, exergetic efficiency (rational efficiency) and the total change in exergy of the two systems. It is concluded that the COP of double effect system is approximately twice the COP of single effect system but the exergetic efficiency of double effect system increase slightly compared to the exergetic efficiency of single effect system. It is found that for each condenser and evaporator temperature, there is an optimum generator temperature where the total change in exergy of the single effect and double effect absorption refrigeration systems is minimum. At this point the COP and exergetic efficiency of the systems become maximum. In this study and when the evaporation temperature is varied from 4 deg. C to 10 deg. C, condenser and absorber temperatures are varied from 33 deg. C to 39 deg. C and generator (HPG) temperature is varied from 60 deg. C to 190 deg. C the maximum COP values of the single effect refrigeration systems are in the range of 0.73-0.79 and for double effect refrigeration systems are in the range of 1.22-1.42. The maximum exergetic efficiency values of the single effect refrigeration systems are in the range of 12.5-23.2% and for double effect refrigeration systems are in the range of 14.3-25.1%.

  17. An In Silico Knockout Model for Gastrointestinal Absorption Using a Systems Pharmacology Approach - Development and Application for Ketones.

    Directory of Open Access Journals (Sweden)

    Vittal Shivva

    Full Text Available Gastrointestinal absorption and disposition of ketones is complex. Recent work describing the pharmacokinetics (PK of d-β-hydroxybutyrate (BHB following oral ingestion of a ketone monoester ((R-3-hydroxybutyl (R-3-hydroxybutyrate found multiple input sites, nonlinear disposition and feedback on endogenous production. In the current work, a human systems pharmacology model for gastrointestinal absorption and subsequent disposition of small molecules (monocarboxylic acids with molecular weight < 200 Da was developed with an application to a ketone monoester. The systems model was developed by collating the information from the literature and knowledge gained from empirical population modelling of the clinical data. In silico knockout variants of this systems model were used to explore the mechanism of gastrointestinal absorption of ketones. The knockouts included active absorption across different regions in the gut and also a passive diffusion knockout, giving 10 gut knockouts in total. Exploration of knockout variants has suggested that there are at least three distinct regions in the gut that contribute to absorption of ketones. Passive diffusion predominates in the proximal gut and active processes contribute to the absorption of ketones in the distal gut. Low doses are predominantly absorbed from the proximal gut by passive diffusion whereas high doses are absorbed across all sites in the gut. This work has provided mechanistic insight into the absorption process of ketones, in the form of unique in silico knockouts that have potential for application with other therapeutics. Future studies on absorption process of ketones are suggested to substantiate findings in this study.

  18. Intervening O vi Quasar Absorption Systems at Low Redshift: A Significant Baryon Reservoir.

    Science.gov (United States)

    Tripp; Savage; Jenkins

    2000-05-01

    Far-UV echelle spectroscopy of the radio-quiet QSO H1821+643 (zem=0.297), obtained with the Space Telescope Imaging Spectrograph (STIS) at approximately 7 km s-1 resolution, reveals four definite O vi absorption-line systems and one probable O vi absorber at 0.15quasar in redshift; these are likely intervening systems unrelated to the background QSO. In the case of the strong O vi system at zabs=0.22497, multiple components are detected in Si iii and O vi as well as H i Lyman series lines, and the differing component velocity centroids and b-values firmly establish that this is a multiphase absorption system. A weak O vi absorber is detected at zabs=0.22637, i.e., offset by approximately 340 km s-1 from the zabs=0.22497 system. Lyalpha absorption is detected at zabs=0.22613, but no Lyalpha absorption is significantly detected at 0.22637. Other weak O vi absorbers at zabs=0.24531 and 0.26659 and the probable O vi system at 0.21326 have widely diverse O vi/H i column density ratios with N(O vi)/N(H i) ranging from systems is Omegab(Ovi&parr0; greater, similar0.0008 h-175. With an assumed metallicity of 1/10 solar and a conservative assumption that the fraction of oxygen in the O vi ionization stage is 0.2, we obtain Omegab(Ovi&parr0; greater, similar0.004 h-175. This is comparable to the combined cosmological mass density of stars and cool gas in galaxies and X-ray-emitting gas in galaxy clusters at low redshift.

  19. Mathematical Model of a Lithium-Bromide/Water Absorption Refrigeration System Equipped with an Adiabatic Absorber

    Directory of Open Access Journals (Sweden)

    Salem M. Osta-Omar

    2016-11-01

    Full Text Available The objective of this paper is to develop a mathematical model for thermodynamic analysis of an absorption refrigeration system equipped with an adiabatic absorber using a lithium-bromide/water (LiBr/water pair as the working fluid. The working temperature of the generator, adiabatic absorber, condenser, evaporator, the cooling capacity of the system, and the ratio of the solution mass flow rate at the circulation pump to that at the solution pump are used as input data. The model evaluates the thermodynamic properties of all state points, the heat transfer in each component, the various mass flow rates, and the coefficient of performance (COP of the cycle. The results are used to investigate the effect of key parameters on the overall performance of the system. For instance, increasing the generator temperatures and decreasing the adiabatic absorber temperatures can increase the COP of the cycle. The results of this mathematical model can be used for designing and sizing new LiBr/water absorption refrigeration systems equipped with an adiabatic absorber or for optimizing existing aforementioned systems.

  20. Optimization of operation of energy supply systems with co-generation and absorption refrigeration

    Directory of Open Access Journals (Sweden)

    Stojiljković Mirko M.

    2012-01-01

    Full Text Available Co-generation systems, together with absorption refrigeration and thermal storage, can result in substantial benefits from the economic, energy and environmental point of view. Optimization of operation of such systems is important as a component of the entire optimization process in pre-construction phases, but also for short-term energy production planning and system control. This paper proposes an approach for operational optimization of energy supply systems with small or medium scale co-generation, additional boilers and heat pumps, absorption and compression refrigeration, thermal energy storage and interconnection to the electric utility grid. In this case, the objective is to minimize annual costs related to the plant operation. The optimization problem is defined as mixed integer nonlinear and solved combining modern stochastic techniques: genetic algorithms and simulated annealing with linear programming using the object oriented “ESO-MS” software solution for simulation and optimization of energy supply systems, developed as a part of this research. This approach is applied to optimize a hypothetical plant that might be used to supply a real residential settlement in Niš, Serbia. Results are compared to the ones obtained after transforming the problem to mixed 0-1 linear and applying the branch and bound method.

  1. A CCD-based system for the detection of DNA in electrophoresis gels by UV absorption

    International Nuclear Information System (INIS)

    Mahon, A.R.; MacDonald, J.H.; Mainwood, A.; Ott, R.J.

    1999-01-01

    A method and apparatus for the detection and quantification of large fragments of unlabelled nucleic acids in agarose gels is presented. The technique is based on ultraviolet (UV) absorption by nucleotides. A deuterium source illuminates individual sample lanes of an electrophoresis gel via an array of optical fibres. As DNA bands pass through the illuminated region of the gel the amount of UV light transmitted is reduced because of absorption by the DNA. During electrophoresis the regions of DNA are detected on-line using a UV-sensitive charge coupled device (CCD). As the absorption coefficient is proportional to the mass of DNA the technique is inherently quantitative. The mass of DNA in a region of the gel is approximately proportional to the integrated signal in the corresponding section of the CCD image. This system currently has a detection limit of less than 1.25 ng compared with 2-10 ng for the most popular conventional technique, ethidium bromide (EtBr) staining. In addition the DNA sample remains in its native state. The removal of the carcinogenic dye from the detection procedure greatly reduces associated biological hazards. (author)

  2. Experimental investigation on photothermal properties of nanofluids for direct absorption solar thermal energy systems

    International Nuclear Information System (INIS)

    He, Qinbo; Wang, Shuangfeng; Zeng, Shequan; Zheng, Zhaozhi

    2013-01-01

    Highlights: • The factors affecting the transmittance of Cu–H 2 O nanofluids were studied with UV–Vis–NIR spectrophotometer. • The optical properties of Cu–H 2 O nanofluids were studied through the theoretical model. • The Cu–H 2 O nanofluids can enhance the absorption ability for solar energy. - Abstract: In this article, Cu–H 2 O nanofluids were prepared through two-step method. The transmittance of nanofluids over solar spectrum (250–2500 nm) was measured by the UV–Vis–NIR spectrophotometer based on integrating sphere principle. The factors influencing transmittance of nanofluids, such as particle size, mass fraction and optical path were investigated. The extinction coefficients measured experimentally were compared with the theoretical calculation value. Meanwhile, the photothermal properties of nanofluids were also investigated. The experimental results show that the transmittance of Cu–H 2 O nanofluids is much less than that of deionized water, and decreases with increasing nanoparticle size, mass fraction and optical depth. The highest temperature of Cu–H 2 O nanofluids (0.1 wt.%) can increased up to 25.3% compared with deionized water. The good absorption ability of Cu–H 2 O nanofluids for solar energy indicates that it is suitable for direct absorption solar thermal energy systems

  3. Enhancement of absorption and hepatoprotective potential through soya-phosphatidylcholine-andrographolide vesicular system.

    Science.gov (United States)

    Jain, Pushpendra Kumar; Khurana, Navneet; Pounikar, Yogesh; Gajbhiye, Asmita; Kharya, Murli Dhar

    2013-06-01

    Andrographis paniculata is a medicinal herb used extensively for various ailments and contains therapeutically active phytoconstituent, andrographolide (AN). Although hepatoprotective activity of AN is established, but their bioavailability is restricted due to its rapid clearance. The aim of this study, therefore, was to formulate AN herbosomes (ANH) through complexation with naturally occurring soya-phosphatidylcholine (SPC), in order to enhance absorption. Prepared andrographolide-soy phosphatidylcholine (AN-SPC) complex prepared was subjected for characterisation of complex and formation of vesicular system known as ANH using rotary evaporation techniques. This complex was subjected to in vitro study using everted small intestine sac technique which showed significantly increased absorption of AN from the ANH as compared to the plain AN. The hepatoprotective potential of ANH and plain AN was evaluated using carbon tetrachloride inducing hepatotoxicity rat model and compared, in which ANH equivalent to 50 mg/kg of plain AN significantly restore serum glutamate oxalacetate transaminase (112.4 ± 9.67 for AN whereas 90.2 ± 4.23 for ANH) and serum glutamate pyruvate transaminase (109.3 ± 7.89 for AN whereas 90.6 ± 4.34 for ANH) level as compared to control group. The ANH showed significantly better absorption than plain AN and this effect of ANH was also comparable to the standard drug (Silymarin). The findings of present study reveal that ANH has better bioavailability as shown by in vitro absorption study and hence improved hepatoprotection as compared to plain AN at equivalent dose.

  4. Continuous monitoring for airborne alpha emitters in a dusty environment

    International Nuclear Information System (INIS)

    Seiler, F.A.; Newton, G.J.; Guilmette, R.A.

    1988-01-01

    Disposal of radioactive wastes in underground facilities requires continuous monitoring for airborne radioactive materials, both on the surface and underground. In addition to a natural background of nonradioactive and radioactive aerosols, there may be a sizeable dust contribution from ongoing work such as mining and vehicular traffic. In the monitoring of alpha-emitting radionuclides, these aerosols may lead to self-absorption in the source and a deterioration of the energy spectrum of the detected alpha particles. In this paper, the influence of a realistic background aerosol on the performance of an alpha monitoring system is evaluated theoretically. It is shown that depositing alpha emitters and background aerosol on a surface for counting leads rapidly to a considerable loss of counts, a deterioration of the alpha spectra, an eventual saturation of the count rates, and interference from the natural background of Rn daughters

  5. Methods to Directly Image Exoplanets around Alpha Centauri and Other Multi-Star Systems

    Science.gov (United States)

    Belikov, R.; Sirbu, D.; Bendek, E.; Pluzhnik, E.

    2017-12-01

    The majority of FGK stars exist as multi-star star systems, and thus form a potentially rich target sample for direct imaging of exoplanets. A large fraction of these stars have starlight leakage from their companion that is brighter than rocky planets. This is in particular true of Alpha Centauri, which is 2.4x closer and about an order of magnitude brighter than any other FGK star, and thus may be the best target for any direct imaging mission, if the light of both stars can be suppressed. Thus, the ability to suppress starlight from two stars improves both the quantity and quality of Sun-like targets for missions such as WFIRST, LUVOIR, and HabEx. We present an analysis of starlight leak challenges in multi-star systems and techniques to solve those challenges, with an emphasis on imaging Alpha Centauri with WFIRST. For the case of internal coronagraphs, the fundamental problem appears to be independent wavefront control of multiple stars (at least if the companion is close enough or bright enough that it cannot simply be removed by longer exposure times or post-processing). We present a technique called Multi-Star Wavefront Control (MSWC) as a solution to this challenge and describe the results of our technology development program that advanced MSWC to TRL 3. Our program consisted of lab demonstrations of dark zones in two-star systems, validated simulations, as well as simulated predictions demonstrating that with this technology, contrasts needed for Earth-like planets are in principle achievable. We also demonstrate MSWC in Super-Nyquist mode, which allows suppression of multiple stars at separations greater than the spatial Nyquist limit of the deformable mirror.

  6. Operating program for an automatic alpha-beta counting system-FAG

    International Nuclear Information System (INIS)

    German, U.; Levinson, L.; Shemesh, Y.; Peled, O.; Weistein, M.

    1996-01-01

    An alpha and beta counting system - FAG, for planchette samples is operated at the Health Physics department's laboratory of the NRCN. The system consists of a proportional detector of 8'' diameter operated in coincidence with a guard detector, an automatic sample changer (FAG-FHT770E) and electronics (FAG- FHT1100 digital counter and controller). The original operation mode of the system was based on manual tasks handled by the FHT1100 electronics. Pin option for a basic computer keyboard operation was available too. A computer with appropriate 110 card was connected to the system and a new operating program was developed which enables full automatic control of the various components. The program includes activity calculations and statistical checks as well as data management. The program which was developed enables computer control of all components of the system, based on bi-directional communication. The computer software controls the FHT1100 electronics using the R5232 protocol and the sample changer by an additional 110 card Contec Inodel PIO-48W(PC). The computer controls the whole operation of the system: change of samples, high voltage change, start, stop etc. It handles in the appropriate order the different commands and operates the electronic and mechanic components accordingly (authors)

  7. Operating program for an automatic alpha-beta counting system-FAG

    Energy Technology Data Exchange (ETDEWEB)

    German, U; Levinson, L; Shemesh, Y; Peled, O; Weistein, M [Israel Atomic Energy Commission, Beersheba (Israel). Nuclear Research Center-Negev

    1996-12-01

    An alpha and beta counting system - FAG, for planchette samples is operated at the Health Physics department`s laboratory of the NRCN. The system consists of a proportional detector of 8`` diameter operated in coincidence with a guard detector, an automatic sample changer (FAG-FHT770E) and electronics (FAG- FHT1100 digital counter and controller). The original operation mode of the system was based on manual tasks handled by the FHT1100 electronics. Pin option for a basic computer keyboard operation was available too. A computer with appropriate 110 card was connected to the system and a new operating program was developed which enables full automatic control of the various components. The program includes activity calculations and statistical checks as well as data management. The program which was developed enables computer control of all components of the system, based on bi-directional communication. The computer software controls the FHT1100 electronics using the R5232 protocol and the sample changer by an additional 110 card Contec Inodel PIO-48W(PC). The computer controls the whole operation of the system: change of samples, high voltage change, start, stop etc. It handles in the appropriate order the different commands and operates the electronic and mechanic components accordingly (authors).

  8. Analysis of aluminium by atomic absorption spectrometry and analysis of thorium and uranium by alpha spectrometry in the black sand of Egypt

    International Nuclear Information System (INIS)

    Hannachi, Dhouha; Mathlouthi, Nadia

    2008-01-01

    Throughout the period of our project of end of study carried out in the Center ; main road Sciences and Nuclear Engineering's CNSTN in one is tallied took one Egypt black sand simple with an aim has of knowing the activities of the existing radio elements and especially Uranium and Thorium. In the same mining, we try to take another Egypt black sand simple an aim has knowing the mass of aluminum by using a techniques in Atomique Absorption Spectrophotometer. After the radio chemical and Spectrometry analysis of the black sand sample we found the results following: - Egypt black sand is contains isotopes of Uranium such as 234 U and 238 U; - The Egypt black sand is contains isotopes of Thorium such as 230 Th and 232 Th. - L' Aluminum is a major. (Author)

  9. Thermo- economical consideration of Regenerative organic Rankine cycle coupling with the absorption chiller systems incorporated in the trigeneration system

    International Nuclear Information System (INIS)

    Anvari, Simin; Taghavifar, Hadi; Parvishi, Alireza

    2017-01-01

    Highlights: • A new trigeneration cycle was studied from a new viewpoint of exergoeconomic and thermodynamic. • Organic Rankine and refrigeration cycles are used for recovery waste heat of cogeneration system. • Application of trigeneration cycles is advantageous in economical and thermodynamic aspects. - Abstract: In this paper, a combined cooling, heating and power cycle is proposed consisting of three sections of gas turbine and heat recovery steam generator cycle, Regenerative organic Rankine cycle, and absorption refrigeration cycle. This trigeneration cycle is subjected to a thorough thermodynamic and exergoeconomic analysis. The principal goal followed in the investigation is to address the thermodynamic and exergoeconomic of a trigeneration cycle from a new prospective such that the economic and thermodynamic viability of incorporating Regenerative organic Rankine cycle, and absorption refrigeration cycle to the gas turbine and heat recovery steam generator cycle is being investigated. Thus, the cost-effectiveness of the introduced method can be studied and further examined. The results indicate that adding Regenerative organic Rankine cycle to gas turbine and heat recovery steam generator cycle leads to 2.5% increase and the addition of absorption refrigeration cycle to the gas turbine and heat recovery steam generator/ Regenerative Organic Rankine cycle would cause 0.75% increase in the exergetic efficiency of the entire cycle. Furthermore, from total investment cost of the trigeneration cycle, only 5.5% and 0.45% results from Regenerative organic Rankine cycle and absorption refrigeration cycles, respectively.

  10. Analysis of a gas absorption system with soluble carrier gas and volatile solvent

    International Nuclear Information System (INIS)

    Kanak, B.E.

    1980-01-01

    The effects of column diameter, carrier gas coabsorption, and solvent vaporization on the performance of a packed gas absorption column are examined. The system investigated employs dichlorodifluoromethane as a solvent to remove krypton from a nitrogen stream and is characterized by substantial nitrogen coabsorption. Three columns with diameters of 2, 3, and 4 inches were constructed and packed with 34.5 inches of Goodloe packing. In addition to the more conventional data, the experimental evaluation of these columns included the use of a radioisotope and a gamma scanning technique which provided direct measurement of the columns' molar krypton profiles. A multicomponent gas absorption model was developed, based on the two-film mass transfer theory, that allows the fluxes of all species to interact. Verification of this model was achieved through comparison of the calculated results with experimental data. With the feed gas flow rate between 6 and 36 lb moles/hr-ft 2 and the solvent feed rate between 40 and 400 lb moles/hr-ft 2 , column diameter was found to have no significant impact on the mass transfer efficiency of this system when carried out in columns with diameters of 2 inches or greater. The absorption of krypton was found to be enhanced and inhibited, respectively, by carrier gas coabsorption and solvent vaporization. An injector system to add gaseous solvent to the feed gas stream prior to its introduction into the packed bed was proposed to eliminate the detrimental effects of solvent vaporization.Using this injector to supersaturate the feed gas stream with solvent enhanced absorber performance in the same manner as carrier gas coabsorption

  11. A solar absorption refrigeration system operating with the mixture ammonia-lithium nitrate

    Energy Technology Data Exchange (ETDEWEB)

    Rivera, W.; Martinez, F.; Garcia-Valladares, O. [Centro de Investigacion en Energia de la Univ. Nacional Autonoma de Mexico, Mor (Mexico); Rivera, C.O. [Univ. Veracruzana, Campus Coatzacoalcos (Mexico)

    2007-07-01

    An intermittent solar absorption refrigeration system for ice production operating with the ammonia-lithium nitrate mixture has been developed in the Centro de Investigacion en Energia of the Universidad Nacional Autonoma de Mexico. The system consists basically of a compound parabolic concentrator (CPC), a generator-absorber, a condenser, a condensate tank, an expansion valve and an evaporator. The system was evaluated in sunny days with insolations above 20 MJ/m{sup 2}-day at different condenser temperatures. The generator temperatures varied from 108 to 121 C and the evaporator temperatures inside the camera from -8 to 0 C. The coefficients of performance (COP) varied from 0.13 to 0.26 depending of the operating temperatures of the system and the solar irradiation. (orig.)

  12. The standard calibration instrument automation system for the atomic absorption spectrophotometer. Part 3: Program documentation

    Science.gov (United States)

    Ryan, D. P.; Roth, G. S.

    1982-04-01

    Complete documentation of the 15 programs and 11 data files of the EPA Atomic Absorption Instrument Automation System is presented. The system incorporates the following major features: (1) multipoint calibration using first, second, or third degree regression or linear interpolation, (2) timely quality control assessments for spiked samples, duplicates, laboratory control standards, reagent blanks, and instrument check standards, (3) reagent blank subtraction, and (4) plotting of calibration curves and raw data peaks. The programs of this system are written in Data General Extended BASIC, Revision 4.3, as enhanced for multi-user, real-time data acquisition. They run in a Data General Nova 840 minicomputer under the operating system RDOS, Revision 6.2. There is a functional description, a symbol definitions table, a functional flowchart, a program listing, and a symbol cross reference table for each program. The structure of every data file is also detailed.

  13. Design and construction of a system to determine Radon-222 through alpha spectroscopy

    International Nuclear Information System (INIS)

    Bonifacio M, J.

    1991-01-01

    The purpose of this work consists in the design a radon-222 gas measurement system utilizing a surface barrier detector with the objective to obtain a more accurate measurement for this isotope through an alpha particle spectrum and so to address as to avoid the activity influence of the descendants of short half-life, which are too beta particles emitters, already other methods it must be correction series to obtain the real value of radon activity. Here are presented the general properties properties of radon, the experimental part description indicating the design to measure the radon-222 gas and its parts, as well as too the standard separation of radium-226 starting from carnotite mineral. Finally, it is presented the results obtained with a discussion about it. (Author) results obtained with a discussion about it. (Author)

  14. PROMETHEE: An Alpha Low Level Waste Assay System Using Passive and Active Neutron Measurement Methods

    International Nuclear Information System (INIS)

    Passard, Christian; Mariani, Alain; Jallu, Fanny; Romeyer-Dherbey, Jacques; Recroix, Herve; Rodriguez, Michel; Loridon, Joel; Denis, Caroline; Toubon, Herve

    2002-01-01

    The development of a passive-active neutron assay system for alpha low level waste characterization at the French Atomic Energy Commission is discussed. Less than 50 Bq[α] (about 50 μg Pu) per gram of crude waste must be measured in 118-l 'European' drums in order to reach the requirements for incinerating wastes. Detection limits of about 0.12 mg of effective 239 Pu in total active neutron counting, and 0.08 mg of effective 239 Pu coincident active neutron counting, may currently be detected (empty cavity, measurement time of 15 min, neutron generator emission of 1.6 x 10 8 s -1 [4π]). The most limiting parameters in terms of performances are the matrix of the drum - its composition (H, Cl...), its density, and its heterogeneity degree - and the localization and self-shielding properties of the contaminant

  15. Development and testing of prototype alpha waste incinerator off-gas systems

    International Nuclear Information System (INIS)

    Freed, E.J.; Becker, G.W.

    1982-01-01

    A test program is in progress at Savannah River Laboratory (SRL) to confirm and develop incinerator design technology for an SRP production Alpha Waste Incinerator (AWI) to be built in the mid-1980's. The Incinerator Components Test Facility (ICTF) is a full-scale (5 kg/h), electrically heated, controlled-air prototype incinerator built to burn nonradioactive solid waste. The incinerator has been operating successfully at SRL since March 1979 and has met or exceeded all design criteria. During the first 1-1/2 years of operation, liquid scrubbers were used to remove particulates and hydrochloric acid from the incinerator exhaust gases. A dry off-gas system is currently being tested to provide data to Savannah River Plant's proposed AWI

  16. An alpha particle measurement system using an energetic neutral helium beam in ITER (invited)

    Energy Technology Data Exchange (ETDEWEB)

    Sasao, M.; Tanaka, N.; Terai, K.; Kaneko, O. [Graduate school of Engineering, Tohoku University, Sendai 980-8579 (Japan); Kisaki, M.; Kobuchi, T.; Tsumori, K.; Okamoto, A.; Kitajima, S. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Shinto, K. [IFMIF R and D Center, Japan Atomic Energy Agency, Rokkasho, Aomori 039-3212 (Japan); Wada, M. [Graduate School of Engineering, Doshisha University, Kyotanabe, Kyoto 610-0321 (Japan)

    2012-02-15

    An energetic helium neutral beam is involved in the beam neutralization measurement system of alpha particles confined in a DT fusion plasma. A full size strong-focusing He{sup +} ion source (2 A, the beam radius of 11.3 mm, the beam energy less than 20 keV). Present strong-focusing He{sup +} ion source shows an emittance diagram separated for each beamlet of multiple apertures without phase space mixing, despite the space charge of a beamlet is asymmetric and the beam flow is non-laminar. The emittance of beamlets in the peripheral region was larger than that of center. The heat load to the plasma electrode was studied to estimate the duty factor for the ITER application.

  17. Investigation of periodically driven systems by x-ray absorption spectroscopy using asynchronous data collection mode

    Science.gov (United States)

    Singh, H.; Donetsky, D.; Liu, J.; Attenkofer, K.; Cheng, B.; Trelewicz, J. R.; Lubomirsky, I.; Stavitski, E.; Frenkel, A. I.

    2018-04-01

    We report the development, testing, and demonstration of a setup for modulation excitation spectroscopy experiments at the Inner Shell Spectroscopy beamline of National Synchrotron Light Source - II. A computer algorithm and dedicated software were developed for asynchronous data processing and analysis. We demonstrate the reconstruction of X-ray absorption spectra for different time points within the modulation pulse using a model system. This setup and the software are intended for a broad range of functional materials which exhibit structural and/or electronic responses to the external stimulation, such as catalysts, energy and battery materials, and electromechanical devices.

  18. Implications of a primordial origin for the dispersion in D/H in quasar absorption systems.

    Science.gov (United States)

    Copi, C J; Olive, K A; Schramm, D N

    1998-03-17

    We explore the difficulties with a primordial origin of variations of D/H in quasar absorption systems. In particular we examine options such as a very large-scale inhomogeneity in the baryon content of the universe. We show that very large-scale (much larger than 1 Mpc) isocurvature perturbations are excluded by current cosmic microwave background observations. Smaller-scale ad hoc perturbations (approximately 1 Mpc) still may lead to a large dispersion in primordial abundances but are subject to other constraints.

  19. Absorption spectra of thin films of triple compounds in the system RbIPbI2

    International Nuclear Information System (INIS)

    Yunakova, O.N.; Miloslavskij, V.K.; Ksenofontova, E.V.; Kovalenko, E.N.

    2012-01-01

    A formation of compounds RbPbI 3 and Rb 4 PbI 6 in the system RbI-PbI 2 is revealed and their absorption spectra are investigated in an energy interval 2-6 eV and a temperatures range 90-500 K. It is established that the low-frequency exciton excitations are localized in PbI 6 4- structural elements of the crystal lattice, they are classified as excitons of intermediate coupling and are of a three-dimensional character in RbPbI 3 and a quasi-two-dimensional one in Rb 4 PbI 6 .

  20. Thermodynamic performance analysis of a vapor compression–absorption cascaded refrigeration system

    International Nuclear Information System (INIS)

    Jain, Vaibhav; Kachhwaha, S.S.; Sachdeva, Gulshan

    2013-01-01

    Highlights: • Study includes first and second law analysis with alternatives refrigerants. • Power consumption in cascaded system is 61% less than vapor compression system. • COP of compression system is improved by 155% with cascaded absorption system. • Condenser is more sensitive to external fluid temperature as compare to evaporator. - Abstract: In the present study, a thermodynamic model for cascaded vapor compression–absorption system (CVCAS) has been developed which consists of a vapor compression refrigeration system (VCRS) coupled with single effect vapor absorption refrigeration system (VARS). Based on first and second laws, a comparative performance analysis of CVCAS and an independent VCRS has been carried out for a design capacity of 66.67 kW. The results show that the electric power consumption in CVCAS is reduced by 61% and COP of compression section is improved by 155% with respect to the corresponding values pertaining to a conventional VCRS. However there is a trade-off between these parameters and the rational efficiency which is found to decrease to half of that for a VCRS. The effect of various operating parameters, i.e., superheating, subcooling, cooling capacity, inlet temperature and the product of effectiveness and heat capacitance of external fluids are extensively studied on the COP, total irreversibility and rational efficiency of the CVCAS. Besides, the performance of environment friendly refrigerants such as R410A, R407C and R134A is found to be almost at par with that of R22. Hence, all the alternative refrigerants selected herein can serve as potential substitutes for R22. Furthermore, it has been found that reducing the irreversibility rate of the condenser by one unit due to decrease in condenser temperature depicted approximately 3.8 times greater reduction in the total irreversibility rate of the CVCAS, whereas unit reduction in the evaporator’s irreversibility rate due to increase in evaporator temperature reduced

  1. Exergy analysis of single effect absorption refrigeration systems: The heat exchange aspect

    International Nuclear Information System (INIS)

    Joybari, Mahmood Mastani; Haghighat, Fariborz

    2016-01-01

    Highlights: • Exergy analysis of LiBr/H 2 O absorption systems with identical COP was carried out. • Exergy destruction rank: absorber followed by generator, condenser and evaporator. • Lower heat source and chilled water inlet temperature reduced exergy destruction. • Higher cooling water inlet temperature reduced exergy destruction. • Lower HTF mass flow rate increased exergy efficiency even for fixed system COP. - Abstract: The main limitation of conventional energy analysis for the thermal performance of energy systems is that this approach does not consider the quality of energy. On the other hand, exergy analysis not only provides information about the systems performance, but also it can specify the locations and magnitudes of losses. A number of studies investigated the effect of parameters such as the component temperature, and heat transfer fluid (HTF) temperature and mass flow rate on the exergetic performance of the same absorption refrigeration system; thus, reported different coefficient of performance (COP) values. However, in this study, the system COP was considered to remain constant during the investigation. This means comparing systems with different heat exchanger designs (based on HTF mass flow rate and temperature) having the same COP value. The effect of HTF mass flow rate and inlet temperature of the cooling water, chilled water and heat source on the outlet specific exergy and exergy destruction rate of each component was investigated. It was found that the lower HTF mass flow rate decreased exergy destruction of the corresponding component. Moreover, the lower temperature of heat source and chilled water inlet increased the system exergetic efficiency. That was also the case for the higher cooling water inlet temperature. Based on the analysis, since the absorber and condenser accounted for a large portion of the total exergy destruction, cooling tower modification with lower cooling water mass flow rate is recommended

  2. Simulation of solar lithium bromide-water absorption cooling system with parabolic trough collector

    International Nuclear Information System (INIS)

    Mazloumi, M.; Naghashzadegan, M.; Javaherdeh, K.

    2008-01-01

    Ahwaz is one of the sweltering cities in Iran where an enormous amount of energy is being consumed to cool residential places in a year. The aim of this research is to simulate a solar single effect lithium bromide-water absorption cooling system in Ahwaz. The solar energy is absorbed by a horizontal N-S parabolic trough collector and stored in an insulated thermal storage tank. The system has been designed to supply the cooling load of a typical house where the cooling load peak is about 17.5 kW (5 tons of refrigeration), which occurs in July. A thermodynamic model has been used to simulate the absorption cycle. The working fluid is water, which is pumped directly to the collector. The results showed that the collector mass flow rate has a negligible effect on the minimum required collector area, but it has a significant effect on the optimum capacity of the storage tank. The minimum required collector area was about 57.6 m 2 , which could supply the cooling loads for the sunshine hours of the design day for July. The operation of the system has also been considered after sunset by saving solar energy

  3. The Research on Programmable Control System of Lithium-Bromide Absorption Refrigerating Air Conditioner Based on the Network

    Directory of Open Access Journals (Sweden)

    Sun Lunan

    2016-01-01

    Full Text Available This article regard the solar lithium-bromide absorption refrigerating air conditioning system as the research object, and it was conducting adequate research of the working principle of lithium bromide absorption refrigerating machine, also it was analyzing the requirements of control system about solar energy air conditioning. Then the solar energy air conditioning control system was designed based on PLC, this system was given priority to field bus control system, and the remote monitoring is complementary, which was combining the network remote monitoring technology. So that it realized the automatic control and intelligent control of new lithium bromide absorption refrigerating air conditioning system with solar energy, also, it ensured the control system can automatically detect and adjust when the external conditions was random changing, to make air conditioning work effectively and steadily, ultimately ,it has great research significance to research the air conditioning control system with solar energy.

  4. Energy and parametric analysis of solar absorption cooling systems in various Moroccan climates

    Directory of Open Access Journals (Sweden)

    Y. Agrouaz

    2017-03-01

    Full Text Available The aim of this work is to investigate the energetic performance of a solar cooling system using absorption technology under Moroccan climate. The solar fraction and the coefficient of performance of the solar cooling system were evaluated for various climatic conditions. It is found that the system operating in Errachidia shows the best average annual solar fraction (of 30% and COP (of 0.33 owing to the high solar capabilities of this region. Solar fraction values in other regions varied between 19% and 23%. Moreover, the coefficient of performance values shows in the same regions a significant variation from 0.12 to 0.33 all over the year. A detailed parametric study was as well carried out to evidence the effect of the operating and design parameters on the solar air conditioner performance.

  5. Open absorption system for cooling and air conditioning using membrane contactors. 2006 annual report

    Energy Technology Data Exchange (ETDEWEB)

    Conde-Petit, M. [M. Conde Engineering, Zuerich (Switzerland); Weber, R. [Materials Science and Technology (EMPA), Abteilung Bautechnologien, Duebendorf (Switzerland)

    2006-11-15

    This illustrated annual report for 2006 for the Swiss Federal Office of Energy (SFOE) reports on work being done on the development of an open absorption system for cooling and air-conditioning. The report reviews the construction of a first prototype and the manufacture of its components. The conceptual design of this new type of air handling unit (AHU), operating with a liquid desiccant, is discussed. The AHU is to be autonomous and the system will not require additional mechanical refrigeration. It is to be thermally driven at temperatures below 80 {sup o}C. Waste heat sources, solar collectors, district heating plants and co-generation systems are targeted as providers of thermal energy at this temperature level. Work carried out is reported on, including that on two-stream membrane contactors.

  6. Thermodynamic analysis of a combined gas turbine, ORC cycle and absorption refrigeration for a CCHP system

    International Nuclear Information System (INIS)

    Mohammadi, Amin; Kasaeian, Alibakhsh; Pourfayaz, Fathollah; Ahmadi, Mohammad Hossein

    2017-01-01

    Highlights: • Thermodynamic analysis of a hybrid CCHP system. • Sensitivity analysis is performed on the most important parameters of the system. • Pressure ratio and gas turbine inlet temperature are the most effective parameters. - Abstract: Hybrid power systems are gained more attention due to their better performance and higher efficiency. Widespread use of these systems improves environmental situation as they reduce the amount of fossil fuel consumption. In this paper a hybrid system composed of a gas turbine, an ORC cycle and an absorption refrigeration cycle is proposed as a combined cooling, heating and power system for residential usage. Thermodynamic analysis is applied on the system. Also a parametric analysis is carried out to investigate the effect of different parameters on the system performance and output cooling, heating and power. The results show that under design conditions, the proposed plant can produce 30 kW power, 8 kW cooling and almost 7.2 ton hot water with an efficiency of 67.6%. Moreover, parametric analysis shows that pressure ratio and gas turbine inlet temperature are the most important and influential parameters. After these two, ORC turbine inlet temperature is the most effective parameter as it can change both net output power and energy efficiency of the system.

  7. Application of vacuum membrane distillation to lithium bromide absorption refrigeration system

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Zanshe; Feng, Shiyu; Li, Yun [School of Energy and Power Engineering, Xi' an Jiaotong University, Xi' an 710049 (China); Gu, Zhaolin [School of Human Settlement and Civil Engineering, Xi' an Jiaotong University, Xi' an 710049 (China)

    2009-11-15

    Conventional generator in lithium bromide absorption refrigeration system is too bulky and heavy to be fitted into small scale device, and the temperature of the driving heater in the generator seems much higher than low grade energy such as regenerative energy or waste heat energy. In this paper, desorption of aqueous lithium bromide solution by vacuum membrane distillation process was presented. Hollow fiber membrane module made by polyvinylidene fluoride was used as desorption device of aqueous lithium bromide solution. Influencing factors of feed flux, feed temperature in lumen side and vacuum pressure in shell side were tested and analyzed with orthogonal test. The results showed that permeation flux of water vapor increased with the feed temperature increasing and the feed flux increasing in lumen side, and the permeation flux also went up along with absolute pressure drop in shell side. Feasibility and potential application analysis shows that the temperature of the driving heat was low and the volume and weight of the desorption device was light. In this study, vacuum membrane distillation to the lithium bromide absorption refrigeration system has proved to be an efficient and cheap desorption mode. (author)

  8. A Lack of Systemic Absorption Following the Repeated Application of Topical Quetiapine in Healthy Adults.

    Science.gov (United States)

    Kayhart, Bryce; Lapid, Maria I; Nelson, Sarah; Cunningham, Julie L; Thompson, Virginia H; Leung, Jonathan G

    2018-01-01

    In the absence of suitable oral or intravenous access for medication administration and when the intramuscular medications are undesirable, alternative routes for drug delivery may be considered. Antipsychotics administered via an inhaled, intranasal, rectal, or topical route have been described in the literature. Topically administered antipsychotics have been previously reported to produce negligible systemic absorption despite being used in clinical practice for nausea and behavioral symptoms associated with dementia. Additionally, the American Academy of Hospice and Palliative Medicine recommends against the use of topical medications that lack supporting literature. Three studies have assessed the systemic absorption of different antipsychotics after administration of only a single, topically applied dose. To evaluate whether the repeated administration of a topically applied antipsychotic may result in detectable serum levels in an accumulating fashion, a pharmacokinetic study was conducted. Five healthy, adult participants consented to receive extemporaneously prepared topical quetiapine in Lipoderm every 4 hours for a total of 5 doses. Blood samples were drawn at baseline and hours 2, 4, 8, 12, 16, and 24, and serum quetiapine concentrations were measured using high-performance liquid chromatography. Quetiapine was undetectable in every sample from 3 participants. Two participants had minimally detectable serum quetiapine levels no sooner than hour 12 of the study period. Extemporaneously prepared quetiapine in Lipoderm resulted in nonexistent or minimal serum level following repeated topical administration. The use of topically applied quetiapine should still be questioned.

  9. Continuous optical measurement system of hemolysis during a photosensitization reaction using absorption spectrum

    Science.gov (United States)

    Hamada, R.; Ogawa, E.; Arai, T.

    2018-02-01

    To investigate hemolysis phenomena during a photosensitization reaction with the reaction condition continuously and simultaneously for a safety assessment of hemolysis side effect, we constructed an optical system to measure blood sample absorption spectrum during the reaction. Hemolysis degree might be under estimated in general evaluation methods because there is a constant oxygen pressure assumption in spite of oxygen depression take place. By investigating hemoglobin oxidation and oxygen desorption dynamics obtained from the contribution of the visible absorption spectrum and multiple regression analysis, both the hemolysis phenomena and its oxygen environment might be obtained with time. A 664 nm wavelength laser beam for the reaction excitation and 475-650 nm light beam for measuring the absorbance spectrum were arranged perpendicularly crossing. A quartz glass cuvette with 1×10 mm in dimensions for the spectrum measurement was located at this crossing point. A red blood cells suspension medium was arranged with low hematocrit containing 30 μg/ml talaporfin sodium. This medium was irradiated up to 40 J/cm2 . The met-hemoglobin, oxygenatedhemoglobin, and deoxygenated-hemoglobin concentrations were calculated by a multiple regression analysis from the measured spectra. We confirmed the met-hemoglobin concentration increased and oxygen saturation decreased with the irradiation time, which seems to indicate the hemolysis progression and oxygen consumption, respectively. By using our measuring system, the hemolysis progression seems to be obtained with oxygen environment information.

  10. Experimental investigation of integrated refrigeration system (IRS) with gas engine, compression chiller and absorption chiller

    International Nuclear Information System (INIS)

    Sun, Z.G.

    2008-01-01

    An integrated refrigeration system (IRS) with a gas engine, a vapor-compression chiller and an absorption chiller is set up and tested. The vapor-compression refrigeration cycle is operated directly by the gas engine. The waste heat from the gas engine operates the absorption refrigeration cycle, which provides additional cooling. The performance of the IRS is described. The cooling capacity of the IRS is about 596 kW, and primary energy ratio (PER) reaches 1.84 at air-conditioning rated conditions. The refrigerating capacity of the prototype increased and PER of prototype decreased with the increase of the gas engine speed. The gas engine speed was preferably regulated at part load condition in order to operate the prototype at high-energy efficiency. The refrigerating capacity and PER of the prototype increased with the increase of the outlet temperature of chilled water or the decrease of the inlet temperature of cooling water. The integrated refrigeration chiller in this work saves running costs as compared to the conventional refrigeration system by using the waste heat

  11. Stochastic resonance in underdamped periodic potential systems with alpha stable Lévy noise

    Science.gov (United States)

    Liu, Ruo-Nan; Kang, Yan-Mei

    2018-06-01

    In this paper, we investigate the effect of alpha stable Lévy noise with alpha stability index α (0 noise (0 noise has a more notable impact on the resonant effect of the asymmetric ratchet potential than that of the symmetric sinusoidal potential because of symmetry breaking.

  12. p25alpha relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy

    DEFF Research Database (Denmark)

    Song, Yun Ju C; Lundvig, Ditte M S; Huang, Yue

    2007-01-01

    cytoplasmic inclusions. Overall, the data indicate that changes in the cellular interactions between MBP and p25alpha occur early in MSA and contribute to abnormalities in myelin and subsequent alpha-synuclein aggregation and the ensuing neuronal degeneration that characterizes this disease....

  13. Interstellar Gas-phase Element Depletions in the Small Magellanic Cloud: A Guide to Correcting for Dust in QSO Absorption Line Systems

    Energy Technology Data Exchange (ETDEWEB)

    Jenkins, Edward B. [Princeton University Observatory, Princeton, NJ 08544-1001 (United States); Wallerstein, George, E-mail: ebj@astro.princeton.edu, E-mail: walleg@u.washington.edu [University of Washington, Seattle, Dept. of Astronomy, Seattle, WA 98195-1580 (United States)

    2017-04-01

    We present data on the gas-phase abundances for 9 different elements in the interstellar medium of the Small Magellanic Cloud (SMC), based on the strengths of ultraviolet absorption features over relevant velocities in the spectra of 18 stars within the SMC. From this information and the total abundances defined by the element fractions in young stars in the SMC, we construct a general interpretation on how these elements condense into solid form onto dust grains. As a group, the elements Si, S, Cr, Fe, Ni, and Zn exhibit depletion sequences similar to those in the local part of our Galaxy defined by Jenkins. The elements Mg and Ti deplete less rapidly in the SMC than in the Milky Way, and Mn depletes more rapidly. We speculate that these differences might be explained by the different chemical affinities to different existing grain substrates. For instance, there is evidence that the mass fractions of polycyclic aromatic hydrocarbons in the SMC are significantly lower than those in the Milky Way. We propose that the depletion sequences that we observed for the SMC may provide a better model for interpreting the element abundances in low-metallicity Damped Lyman Alpha (DLA) and sub-DLA absorption systems that are recorded in the spectra of distant quasars and gamma-ray burst afterglows.

  14. Corneal Absorption of a New Riboflavin-Nanostructured System for Transepithelial Collagen Cross-Linking

    Science.gov (United States)

    Bottos, Katia M.; Oliveira, Anselmo G.; Bersanetti, Patrícia A.; Nogueira, Regina F.; Lima-Filho, Acácio A. S.; Cardillo, José A.; Schor, Paulo; Chamon, Wallace

    2013-01-01

    Corneal collagen cross-linking (CXL) has been described as a promising therapy for keratoconus. According to standard CXL protocol, epithelium should be debrided before treatment to allow penetration of riboflavin into the corneal stroma. However, removal of the epithelium can increase procedure risks. In this study we aim to evaluate stromal penetration of a biocompatible riboflavin-based nanoemulsion system (riboflavin-5-phosphate and riboflavin-base) in rabbit corneas with intact epithelium. Two riboflavin nanoemulsions were developed. Transmittance and absorption coefficient were measured on corneas with intact epithelia after 30, 60, 120, 180, and 240 minutes following exposure to either the nanoemulsions or standard 0.1% or 1% riboflavin-dextran solutions. For the nanoemulsions, the epithelium was removed after measurements to assure that the riboflavin had passed through the hydrophobic epithelium and retained within the stroma. Results were compared to de-epithelialized corneas exposed to 0.1% riboflavin solution and to the same riboflavin nanoemulsions for 30 minutes (standard protocol). Mean transmittance and absorption measured in epithelialized corneas receiving the standard 0.1% riboflavin solution did not reach the levels found on the debrided corneas using the standard technique. Neither increasing the time of exposure nor the concentration of the riboflavin solution from 0.1% to 1% improved riboflavin penetration through the epithelium. When using riboflavin-5-phosphate nanoemulsion for 240 minutes, we found no difference between the mean absorption coefficients to the standard cross-linking protocol (p = 0.54). Riboflavin nanoemulsion was able to penetrate the corneal epithelium, achieving, after 240 minutes, greater stromal concentration when compared to debrided corneas with the standard protocol (p = 0.002). The riboflavin-5-phosphate nanoemulsion diffused better into the stroma than the riboflavin-base nanoemulsion. PMID:23785497

  15. Identification of MgII Absorption Line Systems from SDSS Quasar ...

    Indian Academy of Sciences (India)

    Motivation. The quasar absorption lines are crucial to our understanding of the Universe since the absorption lines provide a wealth of information on the gaseous Universe from high redshift to present day. The absorption lines can also allow us to probe the metallicity and ionization state of the gas (Wild et al. 2008).

  16. Inhibition of two-photon absorption in a three-level system with a pair of bichromatic fields

    International Nuclear Information System (INIS)

    Zou Jinhua; Hu Xiangming; Cheng Guangling; Li Xing; Du Dan

    2005-01-01

    We study two-photon absorption in a three-level ladder atomic system driven by a pair of bichromatic fields of equal frequency differences. The high-frequency component of one bichromatic field and the low-frequency component of the other are on two-photon resonance. The transition probability is calculated by employing the method of harmonic expansion and matrix inversion. Unexpectedly, when the sums of the phases of the different pairs of field components on the two-photon resonance are equal to each other, two-photon absorption is dramatically suppressed and the atomic system becomes transparent against two-photon absorption. Physically, due to dynamical Stark splitting, the two-photon transitions induced by the different pairs of field components experience different dressed states with phase difference of π. As a result, destructive interference occurs between the two pathways and leads to the inhibition of two-photon absorption

  17. Three-dimensional atom localization via probe absorption in a cascade four-level atomic system

    Directory of Open Access Journals (Sweden)

    Zeng Wei

    2018-03-01

    Full Text Available For an atomic system with cascade four-level type, a useful scheme about three-dimensional (3D atom localization is proposed. In our scheme the atomic system is coherently controlled by using a radio-frequency field to couple with two-folded levels under the condition of the existence of probe absorption. Our results show that detecting precision of 3D atom localization may be obviously improved by properly adjusting the frequency detuning and strength of the radio-frequency driving field. So our scheme could be helpful to realize 3D atom localization with high-efficiency and high-precision . In the field of laser cooling or the atom nano-lithography, our studies provide potential applications.

  18. Three-dimensional atom localization via probe absorption in a cascade four-level atomic system

    Science.gov (United States)

    Zeng, Wei; Deng, Li; Chen, Aixi

    2018-03-01

    For an atomic system with cascade four-level type, a useful scheme about three-dimensional (3D) atom localization is proposed. In our scheme the atomic system is coherently controlled by using a radio-frequency field to couple with two-folded levels under the condition of the existence of probe absorption. Our results show that detecting precision of 3D atom localization may be obviously improved by properly adjusting the frequency detuning and strength of the radio-frequency driving field. So our scheme could be helpful to realize 3D atom localization with high-efficiency and high-precision . In the field of laser cooling or the atom nano-lithography, our studies provide potential applications.

  19. Energy and Exergy Based Optimization of Licl-Water Absorption Cooling System

    Directory of Open Access Journals (Sweden)

    Bhargav Pandya

    2017-06-01

    Full Text Available This study presents thermodynamic analysis and optimization of single effect LiCl-H2O absorption cooling system. Thermodynamic models are employed in engineering equation solver to compute the optimum performance parameters. In this study, cut off temperature to operate system has been obtained at various operating temperatures. Analysis depicts that on 3.59 % rise in evaporator temperature, the required cut-off temperature decreased by 12.51%. By realistic comparison between thermodynamic first and second law analysis, optimum generator temperature relative to energy and exergy based prospective has been evaluated. It is found that optimum generator temperature is strong function of evaporator and condenser temperature. Thus, it is feasible to find out optimum generator temperature for various combinations of evaporator and condenser temperatures. Contour plots of optimum generator temperature for several combinations of condenser and absorber temperatures have been also depicted.

  20. A new scanning system for alpha decay events as calibration sources for range-energy relation in nuclear emulsion

    Science.gov (United States)

    Yoshida, J.; Kinbara, S.; Mishina, A.; Nakazawa, K.; Soe, M. K.; Theint, A. M. M.; Tint, K. T.

    2017-03-01

    A new scanning system named "Vertex picker" has been developed to rapid collect alpha decay events, which are calibration sources for the range-energy relation in nuclear emulsion. A computer-controlled optical microscope scans emulsion layers exhaustively, and a high-speed and high-resolution camera takes their micrographs. A dedicated image processing picks out vertex-like shapes. Practical operations of alpha decay search were demonstrated by emulsion sheets of the KEK-PS E373 experiment. Alpha decays of nearly 28 events were detected in eye-check work on a PC monitor per hour. This yield is nearly 20 times more effective than that by the conventional eye-scan method. The speed and quality is acceptable for the coming new experiment, J-PARC E07.

  1. A new scanning system for alpha decay events as calibration sources for range-energy relation in nuclear emulsion

    International Nuclear Information System (INIS)

    Yoshida, J.; Kinbara, S.; Mishina, A.; Nakazawa, K.; Soe, M.K.; Theint, A.M.M.; Tint, K.T.

    2017-01-01

    A new scanning system named “Vertex picker” has been developed to rapid collect alpha decay events, which are calibration sources for the range-energy relation in nuclear emulsion. A computer-controlled optical microscope scans emulsion layers exhaustively, and a high-speed and high-resolution camera takes their micrographs. A dedicated image processing picks out vertex-like shapes. Practical operations of alpha decay search were demonstrated by emulsion sheets of the KEK-PS E373 experiment. Alpha decays of nearly 28 events were detected in eye-check work on a PC monitor per hour. This yield is nearly 20 times more effective than that by the conventional eye-scan method. The speed and quality is acceptable for the coming new experiment, J-PARC E07.

  2. New evaluation of alpha decay half-life of 190Pt isotope for the Pt-Os dating system

    International Nuclear Information System (INIS)

    Tavares, O.A.P.; Medeiros, E.L.; Terranova, M.L.

    2005-08-01

    A semiempirical model based on the quantum mechanical tunnelling mechanism of alpha emission from nuclei has been used to evaluate the half-life of the Pt isotopes. For the important naturally occurring 190 Pt isotope, the radiogenic parent in the 190 Pt → 186 Os dating system, the model yielded a half-life value of (3.7± 0.3) versus 10 11 y. This is comparable to (3.2±0.1) versus 10 11 y which was obtained in the last direct counting experiment to measure the alpha activity of 190 Pt (Tavares and Terranova, Rad. Measurem. 27 (1997) 19). A literature survey of available alpha decay half-life values for 190 Pt isotope is also reported. The significant discrepancies found between data obtained by direct counting, indirect geological methods and different calculation models are analysed and discussed. (author)

  3. Altered TNF-Alpha, Glucose, Insulin and Amino Acids in Islets Langerhans Cultured in a Microgravity Model System

    Science.gov (United States)

    Tobin, Brian W.; Leeper-Woodford, Sandra K.; Hashemi, Brian B.; Smith, Scott M.; Sams, Clarence F.

    2001-01-01

    The present studies were designed to determine effects of a microgravity model system upon lipopolysaccharide (LPS) stimulated tumor necrosis factor alpha (TNF-alpha) activity and indices of insulin and fuel homeostasis of pancreatic islets of Langerhans. Islets (1726+/-1 17,150 u IEU) from Wistar Furth rats were treated as: 1) HARV (High Aspect Ratio Vessel cell culture) , 2) HARV plus LPS, 3) static culture, 4) static culture plus LPS. TNF-alpha (L929 cytotoxicity assay) was significantly increased in LPS-induced HARV and static cultures, yet the increase was more pronounced in the static culture group (palpha production of pancreatic islets of Langerhans, favoring a lesser TNF activity in the HARV. These alterations in fuel homeostasis may be promulgated by gravity averaged cell culture methods or by three dimensional cell assembly.

  4. Vibration energy absorption in the whole-body system of a tractor operator.

    Science.gov (United States)

    Szczepaniak, Jan; Tanaś, Wojciech; Kromulski, Jacek

    2014-01-01

    Many people are exposed to whole-body vibration (WBV) in their occupational lives, especially drivers of vehicles such as tractor and trucks. The main categories of effects from WBV are perception degraded comfort interference with activities-impaired health and occurrence of motion sickness. Absorbed power is defined as the power dissipated in a mechanical system as a result of an applied force. The vibration-induced injuries or disorders in a substructure of the human system are primarily associated with the vibration power absorption distributed in that substructure. The vibration power absorbed by the exposed body is a measure that combines both the vibration hazard and the biodynamic response of the body. The article presents measurement method for determining vibration power dissipated in the human whole body system called Vibration Energy Absorption (VEA). The vibration power is calculated from the real part of the force-velocity cross-spectrum. The absorbed power in the frequency domain can be obtained from the cross-spectrum of the force and velocity. In the context of the vibration energy transferred to a seated human body, the real component reflects the energy dissipated in the biological structure per unit of time, whereas the imaginary component reflects the energy stored/released by the system. The seated human is modeled as a series/parallel 4-DOF dynamic models. After introduction of the excitation, the response in particular segments of the model can be analyzed. As an example, the vibration power dissipated in an operator has been determined as a function of the agricultural combination operating speed 1.39 - 4.16 ms(-1).

  5. Vibration energy absorption in the whole-body system of a tractor operator

    Directory of Open Access Journals (Sweden)

    Jan Szczepaniak

    2014-06-01

    Full Text Available Many people are exposed to whole-body vibration (WBV in their occupational lives, especially drivers of vehicles such as tractor and trucks. The main categories of effects from WBV are perception degraded comfort interference with activities-impaired health and occurrence of motion sickness. Absorbed power is defined as the power dissipated in a mechanical system as a result of an applied force. The vibration-induced injuries or disorders in a substructure of the human system are primarily associated with the vibration power absorption distributed in that substructure. The vibration power absorbed by the exposed body is a measure that combines both the vibration hazard and the biodynamic response of the body. The article presents measurement method for determining vibration power dissipated in the human whole body system called Vibration Energy Absorption (VEA. The vibration power is calculated from the real part of the force-velocity cross-spectrum. The absorbed power in the frequency domain can be obtained from the cross-spectrum of the force and velocity. In the context of the vibration energy transferred to a seated human body, the real component reflects the energy dissipated in the biological structure per unit of time, whereas the imaginary component reflects the energy stored/released by the system. The seated human is modeled as a series/parallel 4-DOF dynamic models. After introduction of the excitation, the response in particular segments of the model can be analyzed. As an example, the vibration power dissipated in an operator has been determined as a function of the agricultural combination operating speed 1.39 – 4.16 ms[sup] -1 [/sup].

  6. Experimental analysis of a diffusion absorption refrigeration system used alternative energy sources

    International Nuclear Information System (INIS)

    Soezen, A.; Oezbas, E.

    2009-01-01

    The continuous-cycle absorption refrigeration device is widely used in domestic refrigerators, and recreational vehicles. It is also used in year-around air conditioning of both homes and larger buildings. The unit consists of four main parts the boiler, condenser, evaporator and the absorber. When the unit operates on kerosene or gas, the heat is supplied by a burner. This element is fitted underneath the central tube. When operating on electricity, the heat is supplied by an element inserted in the pocket. No moving parts are employed. The operation of the refrigerating mechanism is based on Dalton's law. In this study, experimental analysis was performed of a diffusion absorption refrigeration system (DARS) used alternative energy sources such as solar, liquid petroleum gas (LPG) sources. Two basic DAR cycles were set up and investigated: i) In the first cycle (DARS-1), the condensate is sub-cooled prior to the evaporator entrance by the coupled evaporator/gas heat exchanger similar with manufactured by Electrolux Sweden. ii) In the second cycle (DARS-2), the condensate is not sub-cooled prior to the evaporator entrance and gas heat exchanger is separated from the evaporator. (author)

  7. Open-ended response theory with polarizable embedding: multiphoton absorption in biomolecular systems.

    Science.gov (United States)

    Steindal, Arnfinn Hykkerud; Beerepoot, Maarten T P; Ringholm, Magnus; List, Nanna Holmgaard; Ruud, Kenneth; Kongsted, Jacob; Olsen, Jógvan Magnus Haugaard

    2016-10-12

    We present the theory and implementation of an open-ended framework for electric response properties at the level of Hartree-Fock and Kohn-Sham density functional theory that includes effects from the molecular environment modeled by the polarizable embedding (PE) model. With this new state-of-the-art multiscale functionality, electric response properties to any order can be calculated for molecules embedded in polarizable atomistic molecular environments ranging from solvents to complex heterogeneous macromolecules such as proteins. In addition, environmental effects on multiphoton absorption (MPA) properties can be studied by evaluating single residues of the response functions. The PE approach includes mutual polarization effects between the quantum and classical parts of the system through induced dipoles that are determined self-consistently with respect to the electronic density. The applicability of our approach is demonstrated by calculating MPA strengths up to four-photon absorption for the green fluorescent protein. We show how the size of the quantum region, as well as the treatment of the border between the quantum and classical regions, is crucial in order to obtain reliable MPA predictions.

  8. Effects of alpha-glucosylhesperidin on the peripheral body temperature and autonomic nervous system.

    Science.gov (United States)

    Takumi, Hiroko; Fujishima, Noboru; Shiraishi, Koso; Mori, Yuka; Ariyama, Ai; Kometani, Takashi; Hashimoto, Shinichi; Nadamoto, Tomonori

    2010-01-01

    We studied the effects of alpha-glucosylhesperidin (G-Hsp) on the peripheral body temperature and autonomic nervous system in humans. We first conducted a survey of 97 female university students about excessive sensitivity to the cold; 74% of them replied that they were susceptible or somewhat susceptible to the cold. We subsequently conducted a three-step experiment. In the first experiment, G-Hsp (500 mg) was proven to prevent a decrease in the peripheral body temperature under an ambient temperature of 24 degrees C. In the second experiment, a warm beverage containing G-Hsp promoted blood circulation and kept the finger temperature higher for a longer time. We finally used a heart-rate variability analysis to study whether G-Hsp changed the autonomic nervous activity. The high-frequency (HF) component tended to be higher, while the ratio of the low-frequency (LF)/HF components tended to be lower after the G-Hsp administration. These results suggest that the mechanism for temperature control by G-Hsp might involve an effect on the autonomic nervous system.

  9. Tri-generation System based on Municipal Waste Gasification, Fuel Cell and an Absorption Chiller

    Directory of Open Access Journals (Sweden)

    Giannis Katsaros

    2018-03-01

    Full Text Available The present work focuses on the design of a novel tri-generation system based on gasification of municipal solid wastes, a solid oxide fuel cell and an ammonia-water absorption chiller. Tri-generation systems can be implemented in buildings such as hospitals and hotels, where there is a continuous and large demand for electricity, heating and cooling. The system is modelled in Aspen Plus and the influence of different operating parameters on the system performance was studied. The findings suggest that low air equivalent ratios and high gasification temperatures enhance the overall system performance. Syngas cleaning with metal sorbents zinc oxide and sodium bicarbonate for the removal of hydrogen sulfide and hydrogen chloride concentrations proved to be very effective, reducing the concentration of contaminants to < 1 ppm (part per million levels. The possibility of covering the demand profiles of a specific building was also investigated: the system could fully meet the electricity and cooling demands, whereas the heat requirements could be satisfied only up to 55%. Moreover, assuming 20 years of operation, the payback period was 4.5 years and the net present value exceeded 5 million euros.

  10. Experimental investigation on charging and discharging performance of absorption thermal energy storage system

    International Nuclear Information System (INIS)

    Zhang, Xiaoling; Li, Minzhi; Shi, Wenxing; Wang, Baolong; Li, Xianting

    2014-01-01

    Highlights: • A prototype of ATES using LiBr/H 2 O was designed and built. • Charging and discharging performances of ATES system were investigated. • ESE and ESD for cooling, domestic hot water and heating were obtained. - Abstract: Because of high thermal storage density and little heat loss, absorption thermal energy storage (ATES) is known as a potential thermal energy storage (TES) technology. To investigate the performance of the ATES system with LiBr–H 2 O, a prototype with 10 kW h cooling storage capacity was designed and built. The experiments demonstrated that charging and discharging processes are successful in producing 7 °C chilled water, 65 °C domestic hot water, or 43 °C heating water to meet the user’s requirements. Characteristics such as temperature, concentration and power variation of the ATES system during charging and discharging processes were investigated. The performance of the ATES system for supplying cooling, heating or domestic hot water was analyzed and compared. The results indicate that the energy storage efficiencies (ESE) for cooling, domestic hot water and heating are 0.51, 0.97, 1.03, respectively, and the energy storage densities (ESD) for cooling, domestic hot water and heating reach 42, 88, 110 kW h/m 3 , respectively. The performance is better than those of previous TES systems, which proves that the ATES system using LiBr–H 2 O may be a good option for thermal energy storage

  11. Safety, tolerability, and systemic absorption of dapivirine vaginal microbicide gel in healthy, HIV-negative women.

    Science.gov (United States)

    Nel, Annalene M; Coplan, Paul; van de Wijgert, Janneke H; Kapiga, Saidi H; von Mollendorf, Claire; Geubbels, Eveline; Vyankandondera, Joseph; Rees, Helen V; Masenga, Gileard; Kiwelu, Ireen; Moyes, Jocelyn; Smythe, Shanique C

    2009-07-31

    To assess the local and systemic safety of dapivirine vaginal gel vs. placebo gel as well as the systemic absorption of dapivirine in healthy, HIV-negative women. Two prospective, randomized, double-blind, placebo-controlled phase I/II studies were conducted at five research centers, four in Africa and one in Belgium. A total of 119 women used dapivirine gel (concentrations of 0.001, 0.002, 0.005, or 0.02%), and 28 used placebo gel twice daily for 42 days. The primary endpoints were colposcopic findings, adverse events, Division of AIDS grade 3 or grade 4 laboratory values, and plasma levels of dapivirine. Safety data were similar for the dapivirine and placebo gels. None of the adverse events with incidence more than 5% occurred with greater frequency in the dapivirine than placebo groups. Similar percentages of placebo and dapivirine gel users had adverse events that were considered by the investigator to be related to study gel. A total of five serious adverse events occurred in the two studies, and none was assessed as related to study gel. Mean plasma concentrations of dapivirine were approximately dose proportional, and, within each dose group, mean concentrations were similar on days 7, 28, and 42. The maximum observed mean concentration was 474 pg/ml in the 0.02% gel group on day 28. Two weeks after the final application of study gel, mean concentrations decreased to 5 pg/ml or less. Twice daily administration of dapivirine vaginal gel for 42 days was safe and well tolerated with low systemic absorption in healthy, HIV-negative women suggesting that continued development is warranted.

  12. Tumor necrosis factor-alpha regulates the Hypocretin system via mRNA degradation and ubiquitination.

    Science.gov (United States)

    Zhan, Shuqin; Cai, Guo-Qiang; Zheng, Anni; Wang, Yuping; Jia, Jianping; Fang, Haotian; Yang, Youfeng; Hu, Meng; Ding, Qiang

    2011-04-01

    Recent studies recognize that Hypocretin system (also known as Orexin) plays a critical role in sleep/wake disorders and feeding behaviors. However, little is known about the regulation of the Hypocretin system. It is also known that tumor necrosis factor alpha (TNF-α) is involved in the regulation of sleep/wake cycle. Here, we test our hypothesis that the Hypocretin system is regulated by TNF-α. Prepro-Hypocretin and Hypocretin receptor 2 (HcrtR2) can be detected at a very low level in rat B35 neuroblastoma cells. In response to TNF-α, Prepro-Hypocretin mRNA and protein levels are down-regulated, and also HcrtR2 protein level is down-regulated in B35 cells. To investigate the mechanism, exogenous rat Prepro-Hypocretin and rat HcrtR2 were overexpressed in B35 cells. In response to TNF-α, protein and mRNA of Prepro-Hypocretin are significantly decreased (by 93% and 94%, respectively), and the half-life of Prepro-Hypocretin mRNA is decreased in a time- and dose-dependent manner. The level of HcrtR2 mRNA level is not affected by TNF-α treatment; however, HcrtR2 protein level is significantly decreased (by 86%) through ubiquitination in B35 cells treated with TNF-α. Downregulation of cellular inhibitor of apoptosis protein-1 and -2 (cIAP-1 and -2) abrogates the HcrtR2 ubiquitination induced by TNF-α. The control green fluorescent protein (GFP) expression is not affected by TNF-α treatment. These studies demonstrate that TNF-α can impair the function of the Hypocretin system by reducing the levels of both Prepro-Hypocretin and HcrtR2. Copyright © 2010 Elsevier B.V. All rights reserved.

  13. Second law-based thermodynamic analysis of water-lithium bromide absorption refrigeration system

    Energy Technology Data Exchange (ETDEWEB)

    Kilic, Muhsin [Department of Mechanical Engineering, Faculty of Engineering and Architecture, Uludag University, TR 16059, Bursa (Turkey)]. E-mail: mkilic@uludag.edu.tr; Kaynakli, Omer [Department of Mechanical Engineering, Faculty of Engineering and Architecture, Uludag University, TR 16059, Bursa (Turkey)

    2007-08-15

    In this study, the first and the second law of thermodynamics are used to analyze the performance of a single-stage water-lithium bromide absorption refrigeration system (ARS) when some working parameters are varied. A mathematical model based on the exergy method is introduced to evaluate the system performance, exergy loss of each component and total exergy loss of all the system components. Parameters connected with performance of the cycle-circulation ratio (CR), coefficient of performance (COP), Carnot coefficient of performance (COP{sub c} ), exergetic efficiency ({xi}) and efficiency ratio ({tau})-are calculated from the thermodynamic properties of the working fluids at various operating conditions. Using the developed model, the effect of main system temperatures on the performance parameters of the system, irreversibilities in the thermal process and non-dimensional exergy loss of each component are analyzed in detail. The results show that the performance of the ARS increases with increasing generator and evaporator temperatures, but decreases with increasing condenser and absorber temperatures. Exergy losses in the expansion valves, pump and heat exchangers, especially refrigerant heat exchanger, are small compared to other components. The highest exergy loss occurs in the generator regardless of operating conditions, which therefore makes the generator the most important component of the cycle.

  14. Second law-based thermodynamic analysis of water-lithium bromide absorption refrigeration system

    International Nuclear Information System (INIS)

    Kilic, Muhsin; Kaynakli, Omer

    2007-01-01

    In this study, the first and the second law of thermodynamics are used to analyze the performance of a single-stage water-lithium bromide absorption refrigeration system (ARS) when some working parameters are varied. A mathematical model based on the exergy method is introduced to evaluate the system performance, exergy loss of each component and total exergy loss of all the system components. Parameters connected with performance of the cycle-circulation ratio (CR), coefficient of performance (COP), Carnot coefficient of performance (COP c ), exergetic efficiency (ξ) and efficiency ratio (τ)-are calculated from the thermodynamic properties of the working fluids at various operating conditions. Using the developed model, the effect of main system temperatures on the performance parameters of the system, irreversibilities in the thermal process and non-dimensional exergy loss of each component are analyzed in detail. The results show that the performance of the ARS increases with increasing generator and evaporator temperatures, but decreases with increasing condenser and absorber temperatures. Exergy losses in the expansion valves, pump and heat exchangers, especially refrigerant heat exchanger, are small compared to other components. The highest exergy loss occurs in the generator regardless of operating conditions, which therefore makes the generator the most important component of the cycle

  15. Theoretical study on the effect of operating conditions on performance of absorption refrigeration system

    Energy Technology Data Exchange (ETDEWEB)

    Kaynakli, Omer; Kilic, Muhsin [Uludag University, Faculty of Engineering and Architecture, Department of Mechanical Engineering, TR-16059, Bursa (Turkey)

    2007-02-15

    In this study, a detailed thermodynamic analysis of the water/lithium bromide absorption refrigeration cycle is performed. The influences of operating temperature and effectiveness of heat exchanger on the thermal loads of components, coefficients of performance (COP{sub c}, COP) and efficiency ratio ({eta}) are investigated. It is concluded that the COP{sub c} and COP values increase with increasing generator and evaporator temperatures but decrease with increasing condenser and absorber temperatures. The {eta} value varies with these temperatures. Also, the effects of solution and refrigerant heat exchangers on the performance, efficiency ratio of the system and fluid temperatures are compared. As a result, it is found that the solution heat exchanger (SHE) has more effect on the investigated parameters than the refrigerant heat exchanger (RHE). While the SHE increases the COP value up to a maximum 44%, the RHE has an effect of only 2.8%. (author)

  16. Diode laser absorption spectroscopy for process control: Sensor system design methodology

    International Nuclear Information System (INIS)

    Berzins, L.V.; Anklam, T.M.; Chambers, F.; Galanti, S.; Haynam, C.A.; Worden, E.F.

    1995-03-01

    A laser absorption spectroscopy (LAS) system has been developed at Lawrence Livermore National Laboratory (LLNL) for process control. LAS has proven itself to be an accurate and reliable method to monitor both density and composition. In this paper the important features and components of an industrial LAS diagnostic are described. Application of this approach to vaporization processes requires careful selection of the species and transitions to be monitored The relative vapor pressure, hyperfine structure, isotopic frequency shifts, and electronic temperature all effect the selection of a particular transition. In this paper we describe the methodology for choosing the optimal transition or transitions. Coevaporation of a titanium-niobium alloy is used to illustrate the methodology. In a related paper, T.M. Anklam et al describe the application of this diagnostic to monitoring and controlling composition in a physical vapor deposition process of industrial interest

  17. Study of laser radar system using the differential absorption method for detection of air pollutants

    Energy Technology Data Exchange (ETDEWEB)

    Inomata, H; Igarashi, T

    1975-11-01

    A laser radar system using the differential absorption method for remote measurement of atmospheric NO/sub 2/ and SO/sub 2/ is studied. A simultaneous two-wavelength dye laser for the transmitter and a simultaneous two-wavelength signal processer for the receiver are developed. In using this technique, one laser shot allows the determination of NO/sub 2/ concentrations with an uncertainty equivalent to 44 ppM times the range interval (in meters). It seems that the technique is most promising for a range-resolved measurement of ambient molecular pollutants, since it has the advantage of canceling the effect of atmospheric variation in a measurement when atmospheric aerosols are used as a distributed reflector.

  18. Comparative study of irreversibilities in an aqua-ammonia absorption refrigeration system

    Energy Technology Data Exchange (ETDEWEB)

    Ataer, O E [Gazi Univ., Ankara (TR). Mechanical Engineering Dept.; Gogus, Y [Middle East Technical Univ., Ankara (Turkey)

    1991-03-01

    Irreversibilities in components of an aqua-ammonia absorption refrigeration system (ARS) have been determined by second law analysis. The components of the ARS are as follows: condenser, evaporator, absorber, generator, pump, expansion valves, mixture heat exchanger and refrigerant heat exchanger. It is assumed that the ammonia concentration at the generator exit is, independent of the other parameters, equal to 0.999 and at the evaporator exit the gas is saturated vapour. Pressure losses between the generator and condenser, and the evaporator and absorber are taken into consideration. In the results the dimensionless exergy loss of each component, the exergetic coefficient of performance, the coefficient of performance and the circulation ratio are given graphically for each different generator, evaporator, condenser and absorber temperature. (author).

  19. Quasar 2175 Å dust absorbers - II. Correlation analysis and relationship with other absorption line systems

    Science.gov (United States)

    Ma, Jingzhe; Ge, Jian; Prochaska, J. Xavier; Zhang, Shaohua; Ji, Tuo; Zhao, Yinan; Zhou, Hongyan; Lu, Honglin; Schneider, Donald P.

    2018-03-01

    We present the cold neutral content (H I and C I gas) of 13 quasar 2175 Å dust absorbers (2DAs) at z = 1.6-2.5 to investigate the correlation between the presence of the UV extinction bump with other physical characteristics. These 2DAs were initially selected from the Sloan Digital Sky Surveys I-III and followed up with the Keck-II telescope and the Multiple Mirror Telescope as detailed in our Paper I. We perform a correlation analysis between metallicity, redshift, depletion level, velocity width, and explore relationships between 2DAs and other absorption line systems. The 2DAs on average have higher metallicity, higher depletion levels, and larger velocity widths than Damped Lyman α absorbers (DLAs) or subDLAs. The correlation between [Zn/H] and [Fe/Zn] or [Zn/H] and logΔV90 can be used as alternative stellar mass estimators based on the well-established mass-metallicity relation. The estimated stellar masses of the 2DAs in this sample are in the range of ˜109 to ˜2 × 1011 M⊙ with a median value of ˜2 × 1010 M⊙. The relationship with other quasar absorption line systems can be described as (1) 2DAs are a subset of Mg II and Fe II absorbers, (2) 2DAs are preferentially metal-strong DLAs/subDLAs, (3) More importantly, all of the 2DAs show C I detections with logN(C I) > 14.0 cm-2, and (4) 2DAs can be used as molecular gas tracers. Their host galaxies are likely to be chemically enriched, evolved, massive (more massive than typical DLA/subDLA galaxies), and presumably star-forming galaxies.

  20. Alpha-bungarotoxin binding to target cell in a developing visual system by carboxylated nanodiamond

    International Nuclear Information System (INIS)

    Liu, K-K; Chen, P-Y; Lee, Tony J F; Chao, J-I; Chen, M-F; Cheng, C-L; Chang, C-C; Ho, Y-P

    2008-01-01

    Biological molecules conjugating with nanoparticles are valuable for applications including bio-imaging, bio-detection, and bio-sensing. Nanometer-sized diamond particles have excellent electronic and chemical properties for bio-conjugation. In this study, we manipulated the carboxyl group produced on the surface of nanodiamond (carboxylated nanodiamond, cND) for conjugating with alpha-bungarotoxin (α-BTX), a neurotoxin derived from Bungarus multicinctus with specific blockade of alpha7-nicotinic acetylcholine receptor (α7-nAChR). The electrostatic binding of cND-α-BTX was mediated by the negative charge of the cND and the positive charge of the α-BTX in physiological pH conditions. Sodium dodecyl sulfate-polyacrylamide gel analysis and matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI/TOF-MS) spectra displayed that α-BTX proteins were conjugated with cND particles via non-covalent bindings. The green fluorescence of the cND particles combining with the red fluorescence of tetramethylrhodamine-labeled α-BTX presented a yellow color at the same location, which indicated that α-BTX proteins were conjugated with cND particles. Xenopus laevis's oocytes expressed the human α7-nAChR proteins by microinjection with α7-nAChR mRNA. The cND-α-BTX complexes were bound to α7-nAChR locating on the cell membrane of oocytes and human lung A549 cancer cells analyzed by laser scanning confocal microscopy. The choline-evoked α7-nAChR-mediated inward currents of the oocytes were blocked by cND-α-BTX complexes in a concentration-dependent manner using two-electrode voltage-clamp recording. Furthermore, the fluorescence intensity of cND-α-BTX binding on A549 cells could be quantified by flow cytometry. These results indicate that cND-conjugated α-BTX still preserves its biological activity in blocking the function of α7-nAChR, and provide a visual system showing the binding of α-BTX to α7-nAChR

  1. Regulation and function of the alpha2 adrenergic autoreceptor in the central nervous system

    International Nuclear Information System (INIS)

    Spengler, R.N.

    1987-01-01

    The purpose of this investigation was to determine whether changes observed in the number of alpha 2 adrenergic receptors in the brain as measured by radioligand binding experiments reflect changes in the function of alpha 2 autoregulatory receptors which are located on noradrenergic nerve terminals. Inhibition by clonidine of field stimulated 3 H-norepinephrine ( 3 H-NE) release from rat hippocampal slices before and after several drug treatments was analyzed to investigate changes in alpha 2 adrenergic receptor function. Clonidine in a concentration-dependent manner inhibited 3 H-NE release. The effect of clonidine was blocked by the specific alpha 2 adrenergic receptor antagonist, idazoxan. The cumulative administration of clonidine generated a smooth and well-fitted log-concentration-effect curve. Results are presented which demonstrate that this technique can be employed to investigate the role of changes in the function of the alpha 2 autoregulatory receptor. The present investigation also examined representatives of four drug classes which have been shown to alter the specific binding of 3 H-clonidine to neural membranes to determine whether changes in the alpha 2 autoregulatory receptor function also occur

  2. A practical relation between atomic numbers and alpha coefficients

    International Nuclear Information System (INIS)

    Lachance, G.R.

    1980-01-01

    A first approximation indicates that fundamental alpha coefficients for a given analyte vary as a function of the ratio of their respective atomic number raised to a power. This simple rule applies mainly at the limits (i.e., when the weight fraction of analyte i, Wsub(i) is of the order of 0.0 or 1.0) in cases of absorption and weak enhancement. The relation thus provides a means of generating coefficients for the system i-k from experimental data obtained on system i-j and a means of verifying experimental alphas, since arrays of coefficients must show a high degree of concordance. (author)

  3. Ab-initio calculations of the hydrogen-uranium system: Surface phenomena, absorption, transport and trapping

    International Nuclear Information System (INIS)

    Taylor, Christopher D.; Scott Lillard, R.

    2009-01-01

    Density functional theory was applied to the initial steps of uranium hydriding: surface phenomena, absorption, bulk transport and trapping. H adsorbs exothermically to the (0 0 1) surface, yet H absorption into the bulk is endothermic, with off-center octahedral absorption having the lowest absorption energy of 0.39 eV, relative to molecular H 2 . H absorption in interstitial sites causes a local softening of the bulk modulus. Diffusion of H in unstrained α-U has a barrier of 0.6 eV. The energy of H absorption adjacent to the chemical impurities C, S, Si was lowered by an amount proportional to the size of the impurity atom, and the resulting lattice strain Si > S > C. Thus, impurities may promote hydriding by providing surfaces or prestrained zones for H uptake.

  4. Developmental changes in the role of a pertussis toxin sensitive guanine nucleotide binding protein in the rat cardiac alpha1-adrenergic system

    International Nuclear Information System (INIS)

    Han, H.M.

    1989-01-01

    During development, the cardiac alpha 1 -adrenergic chronotropic response changes from positive in the neonate to negative in the adult. This thesis examined the possibility of a developmental change in coupling of a PT-sensitive G-protein to the alpha 1 -adrenergic receptor. Radioligand binding experiments performed with the iodinated alpha 1 -selective radioligand [ 125 I]-I-2-[β-(4-hydroxphenyl)ethylaminomethyl]tetralone ([ 125 I]-IBE 2254) demonstrated that the alpha 1 -adrenergic receptor is coupled to a G-protein in both neonatal and adult rat hearts. However, in the neonate the alpha 1 -adrenergic receptor is coupled to a PT-insensitive G-protein, whereas in the adult the alpha 1 -adrenergic receptor is coupled to both a PT-insensitive and a PT-sensitive G-protein. Consistent with the results from binding experiments, PT did not have any effect on the alpha 1 -mediated positive chronotropic response in the neonate, whereas in the adult the alpha 1 -mediated negative chronotropic response was completely converted to a positive one after PT-treatment. This thesis also examined the possibility of an alteration in coupling of the alpha 1 -adrenergic receptor to its effector under certain circumstances such as high potassium (K + ) depolarization in nerve-muscle (NM) co-cultures, a system which has been previously shown to be a convenient in vitro model to study the mature inhibitory alpha 1 -response

  5. Extracellular overexpression of recombinant Thermobifida fusca cutinase by alpha-hemolysin secretion system in E. coli BL21(DE3

    Directory of Open Access Journals (Sweden)

    Su Lingqia

    2012-01-01

    Full Text Available Abstract Background Extracellular expression of proteins has an absolute advantage in a large-scale industrial production. In our previous study, Thermobifida fusca cutinase, an enzyme mainly utilized in textile industry, was expressed via type II secretory system in Escherichia coli BL21(DE3, and it was found that parts of the expressed protein was accumulated in the periplasmic space. Due to the fact that alpha-hemolysin secretion system can export target proteins directly from cytoplasm across both cell membrane of E. coli to the culture medium, thus in the present study we investigated the expression of cutinase using this alpha-hemolysin secretion system. Results T. fusca cutinase was fused with the specific signal peptide of alpha-hemolysin scretion system and expressed in E. coli BL21(DE3. In addition, HlyB and HlyD, strain-specific translocation components of alpha-hemolysin secretion system, were coexpressed to facilitate the enzyme expression. The cultivation of this engineered cell showed that cutinase activity in the culture medium reached 334 U/ml, which is 2.5 times that from type II secretion pathway under the same culture condition. The recombinant cutinase was further purified. Biochemical characterization of purified enzyme, which had an α-hemolysin secretion pathway signal peptide attached, had substrate specificity, pH and temperature profile, as well as application capability in bioscouring similar to that of wild-type cutinase. Conclusions In the present study, T. fusca cutinase was successfully secreted to the culture media by α-hemolysin secretion system. This is the first report of cutinase being efficiently secreted by this pathway. Due to the limited cases of successful expression of industrial enzyme by E. coli α-hemolysin secretion system, our study further explored the utilization of this pathway in industrial enzymes.

  6. Solar-assisted absorption air-conditioning systems in buildings: Control strategies and operational modes

    International Nuclear Information System (INIS)

    Shirazi, Ali; Pintaldi, Sergio; White, Stephen D.; Morrison, Graham L.; Rosengarten, Gary; Taylor, Robert A.

    2016-01-01

    Highlights: • A simulation model of a solar driven absorption chiller is developed in detail. • Three control strategies were proposed in the solar loop of the plant. • Series and parallel auxiliary heater arrangements were investigated. • The results showed the auxiliary-heater in parallel outperformed the series one. • Solar fraction can be increased by 20% by implementing the proposed configuration. - Abstract: Solar-assisted cooling technology has enormous potential for air-conditioning applications since both solar energy supply and cooling energy demand are well correlated. Unfortunately, market uptake of solar cooling technologies has been slow due to the high capital cost and limited design/operational experience. In the present work, different designs and operational modes for solar heating and cooling (SHC) absorption chiller systems are investigated and compared in order to identify the preferred design strategies for these systems. Three control scenarios are proposed for the solar collector loop. The first uses a constant flow pump, while the second and third control schemes employ a variable speed pump, where the solar collector (SC) set-point temperature could be either fixed or adjusted to the required demand. Series and parallel arrangements, between the auxiliary heater and the storage tank, have been examined in detail from an energy efficiency perspective. A simulation model for different system layouts is developed in the transient system simulation environment (TRNSYS, Version 17). Simulation results revealed that the total solar fraction of the plant is increased by up to 11% when a variable speed solar loop pump is used to achieve a collector set-point temperature adjusted according to the building load demand. Another significant finding of this study is that a parallel configuration for the auxiliary heater out-performs a conventional series configuration. The yearly performance of an auxiliary heater in parallel with the storage

  7. Cardiovascular safety of the oral controlled absorption system (OCAS) formulation of tamsulosin compared to the modified release (MR) formulation

    NARCIS (Netherlands)

    Michel, M. C.; Korstanje, C.; Klauwinkel, W.; Shear, M.; Davies, J.; Quartel, A.

    2005-01-01

    Objective: The potential to interfere with efferent adrenergic drive in the cardiovascular system was tested in elderly healthy subjects for the new oral controlled absorption system (OCAS) 0.4 mg tablet formulation of tamsulosin compared to the modified release (MR) 0.4 mg capsule formulation of

  8. X-ray absorption spectroscopy in biological systems. Opportunities and limitations

    Energy Technology Data Exchange (ETDEWEB)

    Bovenkamp, Gudrun Lisa

    2013-05-15

    X-ray absorption spectroscopy has become more important for applications in the material sciences, geology, environmental science and biology, specifically in the field of molecular biology. The scope of this thesis is to add more experimental evidence in order to show how applicable X-ray absorption near edge structure (XANES) is to biology. Two biological systems were investigated, at the molecular level, lead uptake in plants and the effect of silver on bacteria. This investigation also included an analysis of the sensitivity of Pb L{sub 3}- and Ag L{sub 3}-XANES spectra with regard to their chemical environment. It was shown that Pb L{sub 3}- and Ag L{sub 3}-XANES spectra are sensitive to an environment with at least differences in the second coordination shell. The non-destructive and element specific properties of XANES are the key advantages that were very important for this investigation. However, in both projects the adequate selection of reference compounds, which required in some cases a chemical synthesis, was the critical factor to determine the chemical speciation and, finally, possible uptake and storage mechanisms for plants and antibacterial mechanisms of silver. The chemical environment of Pb in roots and leaves of plants from four different plant families and a lichen from a former lead mining site in the Eifel mountains in Germany was determined using both solid compounds and aqueous solutions of different ionic strength, which simulate the plant environment. The results can be interpreted in such a way that lead is sorbed on the surface of cell walls. Silver bonding as reaction with Staphylococcus aureus, Listeria monocytogenes, and Escherichia coli bacteria was determined using inorganic silver compounds and synthesized silver amino acids. Silver binds to sulfur, amine and carboxyl groups in amino acids.

  9. X-ray absorption spectroscopy in biological systems. Opportunities and limitations

    International Nuclear Information System (INIS)

    Bovenkamp, Gudrun Lisa

    2013-05-01

    X-ray absorption spectroscopy has become more important for applications in the material sciences, geology, environmental science and biology, specifically in the field of molecular biology. The scope of this thesis is to add more experimental evidence in order to show how applicable X-ray absorption near edge structure (XANES) is to biology. Two biological systems were investigated, at the molecular level, lead uptake in plants and the effect of silver on bacteria. This investigation also included an analysis of the sensitivity of Pb L 3 - and Ag L 3 -XANES spectra with regard to their chemical environment. It was shown that Pb L 3 - and Ag L 3 -XANES spectra are sensitive to an environment with at least differences in the second coordination shell. The non-destructive and element specific properties of XANES are the key advantages that were very important for this investigation. However, in both projects the adequate selection of reference compounds, which required in some cases a chemical synthesis, was the critical factor to determine the chemical speciation and, finally, possible uptake and storage mechanisms for plants and antibacterial mechanisms of silver. The chemical environment of Pb in roots and leaves of plants from four different plant families and a lichen from a former lead mining site in the Eifel mountains in Germany was determined using both solid compounds and aqueous solutions of different ionic strength, which simulate the plant environment. The results can be interpreted in such a way that lead is sorbed on the surface of cell walls. Silver bonding as reaction with Staphylococcus aureus, Listeria monocytogenes, and Escherichia coli bacteria was determined using inorganic silver compounds and synthesized silver amino acids. Silver binds to sulfur, amine and carboxyl groups in amino acids.

  10. Advanced Sine Wave Modulation of Continuous Wave Laser System for Atmospheric CO2 Differential Absorption Measurements

    Science.gov (United States)

    Campbell, Joel F.; Lin, Bing; Nehrir, Amin R.

    2014-01-01

    NASA Langley Research Center in collaboration with ITT Exelis have been experimenting with Continuous Wave (CW) laser absorption spectrometer (LAS) as a means of performing atmospheric CO2 column measurements from space to support the Active Sensing of CO2 Emissions over Nights, Days, and Seasons (ASCENDS) mission.Because range resolving Intensity Modulated (IM) CW lidar techniques presented here rely on matched filter correlations, autocorrelation properties without side lobes or other artifacts are highly desirable since the autocorrelation function is critical for the measurements of lidar return powers, laser path lengths, and CO2 column amounts. In this paper modulation techniques are investigated that improve autocorrelation properties. The modulation techniques investigated in this paper include sine waves modulated by maximum length (ML) sequences in various hardware configurations. A CW lidar system using sine waves modulated by ML pseudo random noise codes is described, which uses a time shifting approach to separate channels and make multiple, simultaneous online/offline differential absorption measurements. Unlike the pure ML sequence, this technique is useful in hardware that is band pass filtered as the IM sine wave carrier shifts the main power band. Both amplitude and Phase Shift Keying (PSK) modulated IM carriers are investigated that exibit perfect autocorrelation properties down to one cycle per code bit. In addition, a method is presented to bandwidth limit the ML sequence based on a Gaussian filter implemented in terms of Jacobi theta functions that does not seriously degrade the resolution or introduce side lobes as a means of reducing aliasing and IM carrier bandwidth.

  11. Experimental study on a project with CHP system basing on absorption cycles

    International Nuclear Information System (INIS)

    Sun, Jian; Fu, Lin; Sun, Fangtian; Zhang, Shigang

    2014-01-01

    A new heat recovery system for the CHP (combined heating and power) is presented, and HRU (heat recovery unit) and AHE (absorption heat exchanger) are invented to improve the total energy efficiency of the conventional CHP system by more than 20%, which are installed at the thermal power plant and the heating substation separately. The HRU could recover the low grade heat of exhausted steam from the turbine directly, and the AHE could decrease the temperature of back water of primary pipe to a lower temperature than that of secondary pipe without changing the flow rate of secondary pipe. A large demonstration project employing this technology has been built in Datong of China. And experimental results of HRU and AHE are presented to evaluate this system. - Highlights: • The total energy efficiency of CHP could by increased by more than 20%. • Temperature of back water of primary pipe could be lower than that of secondary pipe. • Heating capacity of primary pipe could be increased significantly. • Low grade heat of exhausted steam from turbine could be recovered directly

  12. Development of a alpha spectrometer system with the surface barrier detector

    International Nuclear Information System (INIS)

    Alencar, Marcus Alexandre Vallini de

    1994-04-01

    The aim of this work is the development of an α spectrometer of low cost and home made technology. The spectrometer is mounted in a double NIM module and includes a surface barrier detector and dedicate electronic system. Six barrier surface detectors were made, three of which with η type silicon wafer 3350 Ω.cm, 270mm 2 and three other with ρ type silicon wafer 5850 Ω.cm and 220mm 2 . The rectifier and the ohmic contacts were prepared at high vacuum (10 -2 to 10 -3 Pa) evaporation with 40μg/cm 2 of Au and Al respectively for the η type detectors, and with Al and Au respectively for the ρ type detectors. The electronic system is composed by a low noise charge sensitive preamplifier with the operational amplifier LF-356 mounted with 1OOMΩ feedback resistor and a 0.5 pF capacitor. The linear amplifier is also based in the LF-356 and the LM-310 operational amplifier. The bipolar output is formatted through a (CR) 2- (RC) 4 shaping network and the unipolar output is obtained through a CR-(RC) 4 shaping system which is sufficient to realize a almost true Gaussian shaping pulse with a time constant of 3.0μs. This format was chosen because we can expect a low counting rate and the gaussian pulse can improve the signal/noise ratio. The first CR differentiation has also a active pole-zero cancellation network.The resolution of detectors for 241 Am α particles at room temperature (24 degree) vary 21 to 44 keV FWHM. The electronic noise of the noise of the system is 7.5 keV FWHM at OpF input capacitance. The overall resolution of the spectrometer was found to be 62 keV FWHM at room temperature. The simplicity of the electronic system, the low cost of the construction and the overall resolution show that this alpha spectrometer can be readily used in measurements where high resolution is not a premium. (author)

  13. Alpha-2 adrenergic stimulation triggers Achilles tenocyte hypercellularity: Comparison between two model systems.

    Science.gov (United States)

    Backman, L J; Andersson, G; Fong, G; Alfredson, H; Scott, A; Danielson, P

    2013-12-01

    The histopathology of tendons with painful tendinopathy is often tendinosis, a fibrosis-like condition of unclear pathogenesis characterized by tissue changes including hypercellularity. The primary tendon cells (tenocytes) have been shown to express adrenoreceptors (mainly alpha-2A) as well as markers of catecholamine production, particularly in tendinosis. It is known that adrenergic stimulation can induce proliferation in other cells. The present study investigated the effects of an exogenously administered alpha-2 adrenergic agonist in an established in vivo Achilles tendinosis model (rabbit) and also in an in vitro human tendon cell culture model. The catecholamine producing enzyme tyrosine hydroxylase and the alpha-2A-adrenoreceptor (α2A AR) were expressed by tenocytes, and alpha-2 adrenergic stimulation had a proliferative effect on these cells, in both models. The proliferation was inhibited by administration of an α2A AR antagonist, and the in vitro model further showed that the proliferative alpha-2A effect was mediated via a mitogenic cell signaling pathway involving phosphorylation of extracellular-signal-regulated kinases 1 and 2. The results indicate that catecholamines produced by tenocytes in tendinosis might contribute to the proliferative nature of the pathology through stimulation of the α2A AR, pointing to a novel target for future therapies. The study furthermore shows that animal models are not necessarily required for all aspects of this research. © 2013 The Authors. Scand J Med Sci Sports published by John Wiley & Sons Ltd.

  14. Modelling the effect of oil/fat content in food systems on flavour absorption by LLDPE.

    NARCIS (Netherlands)

    Dekker, M.; Willige, van R.W.G.; Linssen, J.P.H.; Voragen, A.G.J.

    2003-01-01

    One of the phenomena in food packaging interactions is flavour absorption. Absorption of flavour compounds from food products into food-packaging materials can result in loss of flavour compounds or an unbalance in the flavour profile changing a product's quality. The food matrix influences the

  15. Evaluation of systemic absorption and renal effects of topical ophthalmic flurbiprofen and diclofenac in healthy cats.

    Science.gov (United States)

    Lanuza, Rick; Rankin, Amy J; KuKanich, Butch; Meekins, Jessica M

    2016-07-01

    To investigate systemic absorption and renal effects of topically applied ophthalmic flurbiprofen and diclofenac in healthy cats. Twelve domestic shorthair cats. Cats were randomly assigned to two treatment groups (n = 6) and administered one drop (approximately 40 μL) of either flurbiprofen 0.03% or diclofenac 0.1% in both eyes four times daily (6 am, 12 pm, 6 pm, and 12 am) for 14 days. Blood samples were collected on days 0, 4, 8, 14, 16, and 17 and analyzed by liquid chromatography and mass spectrometry for flurbiprofen and diclofenac plasma concentrations. A complete blood count (CBC), serum chemistry, and urinalysis were analyzed at the beginning of the study (Day 0) and at the end of topical drug administration (Day 15). Both drugs demonstrated systemic absorption. Flurbiprofen was detected (mean ± SD) at day 4 (237 ± 65 ng/mL), day 8 (396 ± 91 ng/mL), day 14 (423 ± 56 ng/mL), day 16 (350 ± 66 ng/mL), and day 17 (270 ± 62 ng/mL), and diclofenac was detected (mean ± SD) at day 4 (130 ± 44 ng/mL), day 8 (131 ± 25 ng/mL), day 14 (150 ± 36 ng/mL), and sporadically on day 16 [corrected]. Flurbiprofen plasma concentration decreased slowly over 48 h after the last dose. No clinically significant abnormalities were noted in the serum blood urea nitrogen, creatinine, or urine specific gravity at the end of topical drug administration compared to the beginning of the study. Flurbiprofen and diclofenac were systemically absorbed after topical administration four times daily to both eyes of healthy cats. Flurbiprofen reached higher plasma concentrations compared to diclofenac. © 2015 American College of Veterinary Ophthalmologists.

  16. Increased severity of experimental autoimmune encephalomyelitis, chronic macrophage/microglial reactivity, and demyelination in transgenic mice producing tumor necrosis factor-alpha in the central nervous system

    DEFF Research Database (Denmark)

    Taupin, V; Renno, T; Bourbonnière, L

    1997-01-01

    are a target of immune attack. TNF-alpha also regulates macrophage activity which could contribute to autoimmune inflammation. We have expressed TNF-alpha at disease-equivalent levels in the central nervous system of transgenic mice, using a myelin basic protein (MBP) promoter. These mice were normal...

  17. SODIUM ABSORPTION SYSTEMS TOWARD SN Ia 2014J ORIGINATE ON INTERSTELLAR SCALES

    Energy Technology Data Exchange (ETDEWEB)

    Maeda, K.; Nogami, D. [Department of Astronomy, Kyoto University, Kitashirakawa-Oiwake-cho, Sakyo-ku, Kyoto 606-8502 (Japan); Tajitsu, A. [Subaru Telescope, National Astronomical Observatory of Japan, 650 North A’ohoku Place, Hilo, HI 96720 (United States); Kawabata, K. S. [Hiroshima Astrophysical Science Center, Hiroshima University, Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8526 (Japan); Foley, R. J. [Astronomy Department, University of Illinois at Urbana-Champaign, 1002 W. Green Street, Urbana, IL 61801 (United States); Honda, S.; Arai, A. [Nishi-Harima Astronomical Observatory, Center for Astronomy, University of Hyogo, 407-2, Nishigaichi, Sayo-cho, Sayo, Hyogo 679-5313 (Japan); Moritani, Y.; Ishigaki, M.; Nomoto, K.; Schramm, M. [Kavli Institute for the Physics and Mathematics of the Universe (WPI), The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8583 (Japan); Tanaka, M.; Aoki, W. [National Astronomical Observatory of Japan, Mitaka, Tokyo 181-8588 (Japan); Hashimoto, O. [Gunma Astronomical Observatory, Takayama, Gunma 377-0702 (Japan); Simon, J. D. [Observatories of the Carnegie Institution for Science, 813 Santa Barbara St, Pasadena, CA 91101 (United States); Phillips, M. M. [Carnegie Observatories, Las Campanas Observatory, Casilla 601, La Serena (Chile); Yamanaka, M. [Department of Physics, Faculty of Science and Engineering, Konan University, Okamoto, Kobe, Hyogo 658-8501 (Japan); Milisavljevic, D.; Soderberg, A. M. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Mazzali, P. A., E-mail: keiichi.maeda@kusastro.kyoto-u.ac.jp [Astrophysics Research Institute, Liverpool John Moores University, Liverpool L3 5RF (United Kingdom); and others

    2016-01-10

    Na i D absorbing systems toward Type Ia supernovae (SNe Ia) have been intensively studied over the last decade with the aim of finding circumstellar material (CSM), which is an indirect probe of the progenitor system. However, it is difficult to deconvolve CSM components from non-variable, and often dominant, components created by interstellar material (ISM). We present a series of high-resolution spectra of SN Ia 2014J from before maximum brightness to ≳250 days after maximum brightness. The late-time spectrum provides unique information for determining the origin of the Na i D absorption systems. The deep late-time observation allows us to probe the environment around the SN at a large scale, extending to ≳40 pc. We find that a spectrum of diffuse light in the vicinity, but not directly in the line of sight, of the SN has absorbing systems nearly identical to those obtained for the “pure” SN line of sight. Therefore, basically all Na i D systems seen toward SN 2014J must originate from foreground material that extends to at least ∼40 pc in projection and none at the CSM scale. A fluctuation in the column densities at a scale of ∼20 pc is also identified. After subtracting the diffuse, “background” spectrum, the late-time Na i D profile along the SN line of sight is consistent with profiles near maximum brightness. The lack of variability on a ∼1 year timescale is consistent with the ISM interpretation for the gas.

  18. Alpha-tocopherol alters endogenous oxidative defense system in mungbean plants under water-deficit condition

    International Nuclear Information System (INIS)

    Sadiq, M.; Akram, N.A.; Javed, M.T.

    2016-01-01

    Foliar spray of plant growth regulating compounds including antioxidants is an effective strategy to overcome the adverse effects of environmental constraints on different plants. A pot experiment was conducted to assess the influence of exogenously applied alpha-tocopherol (Toc) in up-regulating the oxidative defense system in two mungbean cultivars (Cyclone 7008 and Cyclone 8009) grown under normal and water deficit conditions. After 30-day of water deficit treatment, four levels of Toc (0 (non spray), 100, 200 and 300 mg L-1) were applied as a foliage application (at vegetative growth stage). A significant reduction was observed in plant height and total soluble proteins, while an increase was observed in the levels of hydrogen peroxide (H/sub 2/O/sub 2/), ascorbic acid, total phenolics, malondialdehyde (MDA), total free amino acids and the activities of enzymatic (SOD, POD and CAT) antioxidants in both mungbean cultivars under drought conditions. Foliar spray of Toc was effective in improving plant height, AsA, total soluble proteins, total free amino acids, and activities of POD and CAT enzymes, but reduced MDA under water stress conditions. However, no prominent change was observed on the concentrations of H/sub 2/O/sub 2/, phenolics, and SOD enzyme due to foliar-applied Toc in both mungbean cultivars under both water regimes. Both mungbean cultivars were almost similar in all attributes measured except that cv. Cyclone 7008 was higher in the levels of H/sub 2/O/sub 2/ and TSP while cv. Cyclone 8009 in phenolics. So, from the results of this study we can suggest that exogenous application of Toc is effective in improving growth and antioxidative potential of mungbean plants under dry arid environment. (author)

  19. Estradiol upregulates calcineurin expression via overexpression of estrogen receptor alpha gene in systemic lupus erythematosus

    Directory of Open Access Journals (Sweden)

    Hui-Li Lin

    2011-04-01

    Full Text Available Systemic lupus erythematosus (SLE is an autoimmune disease primarily affecting women (9:1 compared with men. To investigate the influence of female sex hormone estrogen on the development of female-biased lupus, we compared the expression of estrogen receptor alpha (ERα gene and protein levels as well as expression of T-cell activation gene calcineurin in response to estrogen in peripheral blood lymphocytes (PBLs from SLE patients and normal controls. PBLs were isolated from 20 female SLE patients and 6 normal female controls. The amount of ERα protein in PBL was measured by flow cytometry. The expression of ERα and calcineurin messenger RNA was measured by semi-quantitative reverse transcription-polymerase chain reaction. Calcineurin phosphatase activity was measured by calcineurin assay kit. The expression of ERα messenger RNA and ERα protein was significantly increased (p=0.001 and p=0.023, respectively in PBL from SLE patients compared with that from normal controls. In addition, the basal calcineurin in PBL from SLE patients was significantly higher (p=0.000 than that from normal controls, and estrogen-induced expression of calcineurin was increased (p=0.007 in PBL from SLE patients compared with that from normal controls, a 3.15-fold increase. This increase was inhibited by the ERα antagonism ICI 182,780. The effects of ER antagonism were also found in calcineurin activity. These data suggest that overexpression of ERα gene and enhanced activation of calcineurin in response to estrogen in PBL may contribute to the pathogenesis of female dominant in SLE.

  20. Determination of mercury by multisyringe flow injection system with cold-vapor atomic absorption spectrometry

    International Nuclear Information System (INIS)

    Leal, L.O.; Elsholz, O.; Forteza, R.; Cerda, V.

    2006-01-01

    A new software-controlled time-based multisyringe flow injection system for mercury determination by cold-vapor atomic absorption spectrometry is proposed. Precise known volumes of sample, reducing agent (1.1% SnCl 2 in 3% HCl) and carrier (3% HCl) are dispensed into a gas-liquid separation cell with a multisyringe burette coupled with one three-way solenoid valve. An argon flow delivers the reduced mercury to the spectrometer. The optimization of the system was carried out testing reaction coils and gas-liquid separators of different design as well as changing parameters, such as sample and reagents volumes, reagent concentrations and carrier gas flow rate, among others. The analytical curves were obtained within the range 50-5000 ng L -1 . The detection limit (3σ b /S) achieved is 5 ng L -1 . The relative standard deviation (R.S.D.) was 1.4%, evaluated from 16 successive injections of 250 ng L -1 Hg standard solution. The injection and sample throughput per hour were 44 and 11, respectively. This technique was validated by means of solid and water reference materials with good agreement with the certified values and was successfully applied to fish samples

  1. Simulator for design absorption refrigeration system; Simulador para projeto de ciclos de refrigeracao por absorcao

    Energy Technology Data Exchange (ETDEWEB)

    Morejon, C.F.M.; Brum, N. de C. [Universidade Federal, Rio de Janeiro, RJ (Brazil). Coordenacao dos Programas de Pos-graduacao de Engenharia. Programa de Engenharia Mecanica]. E-mails: Camilo_freddy@hotmail.com; Nisio@serv.com.ufrj.br

    2000-07-01

    This work presents a development of a thermal fluid dynamics model and a solution of a steady state absorption refrigeration cycle, with ammonia water as the working fluid. Analytical thermodynamics models expressing the enthalpy in function of pressure, temperature and composition (h=f(P,T,x)), are used with the aim to design all of the cycle devices, moved by any type of energy such as solar, natural gas, steam or electrical energy (Morejon and Hackenberg, 1978). The development of the analysis is carried out by the application of thermal fluid dynamics concepts together with a detailed study of the heat and mass transfer in the different cycle stages. The thermodynamic cycle model, obtained from equation of state for ammonia - water mixtures (Ziegker and Trepp, 1984), is represented by the relation h - x (enthalpy-composition) for different pressures and temperatures. The obtained models are used to implement computational codes in MAPLE-V facilitating the design and simulation of refrigeration system. This study can be applied in the systems of air conditioning and refrigeration chambers design. (author)

  2. Quantitative autoradiography of alpha particle emission in geo-materials using the Beaver™ system

    Energy Technology Data Exchange (ETDEWEB)

    Sardini, Paul; Angileri, Axel [IC2MP Equipe HydrASA, 6 Rue Michel Brunet, B35, TSA 51106 Poitiers Cedex 9 (France); Descostes, Michael [AREVA Mines, R& D Department, Paris (France); Duval, Samuel; Oger, Tugdual [AI4R SAS, Nantes (France); Patrier, Patricia [IC2MP Equipe HydrASA, 6 Rue Michel Brunet, B35, TSA 51106 Poitiers Cedex 9 (France); Rividi, Nicolas [Service Camparis, Université Pierre et Marie Curie, Paris (France); Siitari-Kauppi, Marja [Radiochemistry Laboratory, University of Helsinki, Helsinki (Finland); Toubon, Hervé [AREVA Mines, R& D Department, Paris (France); Donnard, Jérôme [AI4R SAS, Nantes (France)

    2016-10-11

    In rocks or artificial geo-materials, radioactive isotopes emitting alpha particles are dispersed according to the mineralogy. At hand specimen scale, the achievement of quantitative chemical mapping of these isotopes takes on a specific importance. Knowledge of the distribution of the uranium and thorium series radionuclides is of prime interest to several disciplines, from the geochemistry of uranium deposits, to the dispersion of uranium mill tailings in the biosphere. The disequilibrium of these disintegration chains is also commonly used for dating. However, some prime importance isotopes, such as {sup 226}Ra, are complicated to localize in geo-materials. Because of its high specific activity, {sup 226}Ra is found in very low concentrations (~ppq), preventing its accurate localization in rock forming minerals. This paper formulates a quantitative answer to the following question: at hand specimen scale, how can alpha emitters in geo-materials be mapped quantitatively? In this study, we tested a new digital autoradiographic method (called the Beaver™) based on a Micro Patterned Gaseous Detector (MPGD) in order to quantitatively map alpha emission at the centimeter scale rock section. Firstly, for two thin sections containing U-bearing minerals at secular equilibrium, we compared the experimental and theoretical alpha count rates, measured by the Beaver™ and calculated from the uranium content, respectively. We found that they are very similar. Secondly, for a set of eight homemade standards made up of a mixture of inactive sand and low-radioactivity mud, we compared the count rates obtained by the Beaver™ and by an alpha spectrometer. The results indicate (i) a linearity between both count rates, and (ii) that the count obtained by the Beaver™ can be estimated from the count obtained by the alpha spectrometry using a factor of 0.82.

  3. Quantitative autoradiography of alpha particle emission in geo-materials using the Beaver™ system

    International Nuclear Information System (INIS)

    Sardini, Paul; Angileri, Axel; Descostes, Michael; Duval, Samuel; Oger, Tugdual; Patrier, Patricia; Rividi, Nicolas; Siitari-Kauppi, Marja; Toubon, Hervé; Donnard, Jérôme

    2016-01-01

    In rocks or artificial geo-materials, radioactive isotopes emitting alpha particles are dispersed according to the mineralogy. At hand specimen scale, the achievement of quantitative chemical mapping of these isotopes takes on a specific importance. Knowledge of the distribution of the uranium and thorium series radionuclides is of prime interest to several disciplines, from the geochemistry of uranium deposits, to the dispersion of uranium mill tailings in the biosphere. The disequilibrium of these disintegration chains is also commonly used for dating. However, some prime importance isotopes, such as 226 Ra, are complicated to localize in geo-materials. Because of its high specific activity, 226 Ra is found in very low concentrations (~ppq), preventing its accurate localization in rock forming minerals. This paper formulates a quantitative answer to the following question: at hand specimen scale, how can alpha emitters in geo-materials be mapped quantitatively? In this study, we tested a new digital autoradiographic method (called the Beaver™) based on a Micro Patterned Gaseous Detector (MPGD) in order to quantitatively map alpha emission at the centimeter scale rock section. Firstly, for two thin sections containing U-bearing minerals at secular equilibrium, we compared the experimental and theoretical alpha count rates, measured by the Beaver™ and calculated from the uranium content, respectively. We found that they are very similar. Secondly, for a set of eight homemade standards made up of a mixture of inactive sand and low-radioactivity mud, we compared the count rates obtained by the Beaver™ and by an alpha spectrometer. The results indicate (i) a linearity between both count rates, and (ii) that the count obtained by the Beaver™ can be estimated from the count obtained by the alpha spectrometry using a factor of 0.82.

  4. Thermodynamic analysis of an absorption refrigeration system with ionic-liquid/refrigerant mixture as a working fluid

    International Nuclear Information System (INIS)

    Kim, Yoon Jo; Kim, Sarah; Joshi, Yogendra K.; Fedorov, Andrei G.; Kohl, Paul A.

    2012-01-01

    Thermodynamics of an ionic-liquid (IL) based absorption refrigeration system has been numerically analyzed. It provides an alternative to the normally toxic working fluids, such as the ammonia in conventional absorption systems. The use of ILs also eliminates crystallization and metal-compatibility problems of the water/LiBr system. Mixtures of refrigerants and imidazolium-based ILs are theoretically explored as the working fluid pairs in a miniature absorption refrigeration system, so as to utilize waste-heat to power a refrigeration/heat pump system for electronics cooling. A non-random two-liquid (NRTL) model was built and used to predict the solubility of the mixtures. Saturation temperatures at the evaporator and condenser were set at 25 °C and 50 °C, respectively, with the power dissipation of 100 W. Water in combination with [emim][BF 4 ] (1-ethyl-3-methylimidazolium tetrafluoroborate) gave the highest coefficient of performance (COP) around 0.9. The refrigerant/IL compatibility indicated by the circulation ratio, alkyl chain length of the IL, and thermodynamic properties of the refrigerants, such as latent heat of evaporation were proven to be important factors in determining the performance of the absorption system. The negative effect of high viscosity was mitigated by dilution of the IL with the refrigerant and the use of slightly larger microfluidic channel heat exchangers. -- Highlights: ► Mixtures of refrigerant/ionic-liquid are studied for absorption system. ► We carry out comprehensive theoretical thermodynamic analysis. ► The essential factors of refrigerant/IL affecting the performance are identified. ► Water/[emim][BF 4 ] showed the best performance of COP. ► The effects of high viscosity ILs on the system performance are not significant.

  5. New waste heat district heating system with combined heat and power based on absorption heat exchange cycle in China

    International Nuclear Information System (INIS)

    Sun Fangtian; Fu Lin; Zhang Shigang; Sun Jian

    2012-01-01

    A new waste heat district heating system with combined heat and power based on absorption heat exchange cycle (DHAC) was developed to increase the heating capacity of combined heat and power (CHP) through waste heat recovery, and enhance heat transmission capacity of the existing primary side district heating network through decreasing return water temperature by new type absorption heat exchanger (AHE). The DHAC system and a conventional district heating system based on CHP (CDH) were analyzed in terms of both thermodynamics and economics. Compared to CDH, the DHAC increased heating capacity by 31% and increased heat transmission capacity of the existing primary side district heating network by 75%. The results showed that the exergetic efficiency of DHAC was 10.41% higher and the product exergy monetary cost was 36.6¥/GJ less than a CHD. DHAC is an effective way to increase thermal utilization factor of CHP, and to reduce district heating cost. - Highlights: ► Absorption heat pumps are used to recover waste heat in CHP. ► Absorption heat exchanger can reduce exergy loss in the heat transfer process. ► New waste heat heating system (DHAC) can increase heating capacity of CHP by 31%. ► DHAC can enhance heat transmission capacity of the primary pipe network by 75%. ► DHAC system has the higher exergetic efficiency and the better economic benefit.

  6. High-pressure phase equilibrium data for systems with carbon dioxide, {alpha}-humulene and trans-caryophyllene

    Energy Technology Data Exchange (ETDEWEB)

    Michielin, Eliane M.Z.; Rosso, Sibele R [EQA/UFSC, Chemical and Food Engineering Department, Federal University of Santa Catarina, C.P. 476, CEP 88040-900, Florianopolis, SC (Brazil); Franceschi, Elton; Borges, Gustavo R; Corazza, Marcos L; Oliveira, J Vladimir [Department of Food Engineering, URI - Campus de Erechim, Av. Sete de Setembro, 1621, Erechim, RS, 99700-000 (Brazil); Ferreira, Sandra R.S. [EQA/UFSC, Chemical and Food Engineering Department, Federal University of Santa Catarina, C.P. 476, CEP 88040-900, Florianopolis, SC (Brazil)], E-mail: sandra@enq.ufsc.br

    2009-01-15

    The aim of this work is to report phase equilibrium data for the binary systems (CO{sub 2} + {alpha}-humulene) and (CO{sub 2} + trans-caryophyllene), and for the ternary system (CO{sub 2} + {alpha}-humulene + trans-caryophyllene). Results from literature show that {alpha}-humulene and trans-caryophyllene are the main compounds responsible for the anti-inflammatory and anti-allergic characteristics attributed to the medicinal plant Cordia verbenacea D.C., hence giving importance to the phase behaviour investigation performed in this work. Phase equilibrium experiments were performed in a high-pressure, variable-volume view cell over the temperature range of T = (303 to 343) K and pressures up to 20 MPa. (Liquid + liquid) and (vapour + liquid + liquid) equilibrium were observed at T = 303 K, while (vapour + liquid) phase transitions were verified to occur from T = (313 to 343) K, for all systems studied. Thermodynamic modelling was performed using the Peng-Robinson equation of state and the classical quadratic mixing rules, with a satisfactory agreement between experimental and calculated values.

  7. The absorption and distribution of Cesium-134 in rice-soil system

    International Nuclear Information System (INIS)

    Xu Yinliang; Chen Chuanqun; Chen Bin; Sun Zhiming

    1991-01-01

    Dynamics of absorption of 134 Cs by rice shows that absorption rate is the fastest at boot stage; absorption capacities of 134 Cs in soils are different with the different physical-chemical properties of soils; absorption amounts vary with the time of irrigating 134 Cs; the closer the irrigation time to mature stage is, the more the absorption amount of 134 Cs in rice will be; the more the irrigating times are, and the higher the radioactivity of 134 Cs in irrigating water is, the more the absorption amount in rice will be. After brown rice is polished, contamination of 134 Cs can be decreased by 22.6-45.6%. The order of specific activity in rice is: bran > root > straw > husk > polished rice. Percentage activity of straw, brown rice, root and husk is 51.4%, 28.4%, 11.8% and 8.4% respectively. The migration of 134 Cs is very slow in soil and 95.1% of 134 Cs is concentrated in surface soil (0-2.5 cm). The distribution ratio of 134 Cs in the rice and soil is 6.1%:93.9%. Potassium ion can inhibit the absorption of 134 Cs by rice. There is an exponential function between the concentration of potassium ion and specific activity of 134 Cs in rice

  8. Does adjuvant systemic therapy with interferon-alpha for stage II-III melanoma prolong survival?

    NARCIS (Netherlands)

    Eggermont, Alexander M. M.; Punt, Cornelis J. A.

    2003-01-01

    The experience with interferon-alpha in malignant melanoma resembles, to some degree, the experience with various kinds of adjuvant immunotherapeutic agents where 25 years of phase III trials of adjuvant therapy in stage II-IIII melanoma have not defined a standard therapy. Most trials failed to

  9. Systemic side effects of isolated limb perfusion with tumor necrosis factor alpha

    NARCIS (Netherlands)

    Zwaveling, Jan Harm

    1997-01-01

    The main function of tumor necrosis factor alpha (TNF-a), a small polypeptide shared by all mammals, is probably protection against invading bacteria, parasites and viruses; killing of these microorganisms is facilitated in the presence of TNF-a. However, as its name suggest, TNF-a is also capable

  10. Agonist-induced affinity alterations of a central nervous system. cap alpha. -bungarotoxin receptor

    Energy Technology Data Exchange (ETDEWEB)

    Lukas, R.J.; Bennett, E.L.

    1979-01-01

    The ability of cholinergic agonists to block the specific interaction of ..cap alpha..-bungarotoxin (..cap alpha..-Bgt) with membrane-bound sites derived from rat brain is enhanced when membranes are preincubated with agonist. Thus, pretreatment of ..cap alpha..-Bgt receptors with agonist (but not antagonist) causes transformation of sites to a high-affinity form toward agonist. This change in receptor state occurs with a half-time on the order of minutes, and is fully reversible on dilution of agonist. The results are consistent with the identity of ..cap alpha..-Bgt binding sites as true central nicotinic acetylcholine receptors. Furthermore, this agonist-induced alteration in receptor state may represent an in vitro correlate of physiological desensitization. As determined from the effects of agonist on toxin binding isotherms, and on the rate of toxin binding to specific sites, agonist inhibition of toxin binding to the high-affinity state is non-competitive. This result suggests that there may exist discrete toxin-binding and agonist-binding sites on central toxin receptors.

  11. Materials and systems developments on solid absorption refrigeration with CaCl2·xNH3

    International Nuclear Information System (INIS)

    Iloeji, O.C.

    1995-10-01

    The paper presents some developments on the stabilization of CaCl 2 for use as a solid absorption material in refrigerators, the development of a refrigerator using the stabilized salt, and computer modelling of the refrigerator system. (author). 8 refs, 19 figs

  12. A comparison of neutron resonance absorption in thermal reactor lattices in the AUS neutronics code system with Monte Carlo calculations

    International Nuclear Information System (INIS)

    Robinson, G.S.

    1985-08-01

    The calculation of resonance shielding by the subgroup method, as incorporated in the MIRANDA module of the AUS neutronics code system, is compared with Monte Carlo calculatons for a number of thermal reactor lattices. For the large range of single rod and rod cluster lattices considered, AUS results for resonance absorption were high by up to two per cent

  13. Three-objective optimization of a novel triple-effect absorption heat transformer combined with a water desalination system

    International Nuclear Information System (INIS)

    Mahmoudi, S.M.S.; Salehi, S.; Yari, M.

    2017-01-01

    Highlights: • A new type of triple-effect absorption heat transformers is proposed. • A temperature lift of 180 °C is obtained by the proposed system. • The proposed system is observed to be the most effective. • The highest distilled water mass flow rate is obtained by the proposed system. - Abstract: A novel triple-effect absorption heat transformer is proposed and compared with a most studied configuration of triple-effect absorption heat transformer and a modified form of it from the viewpoint of exergoeconomics. All systems are integrated with water desalination system to produced distilled water. Sensitivity analyses are performed to identify the influence on the systems’ performance of such decision parameters as the temperatures of evaporator, condenser, absorber and absorbing evaporators for all the configurations. Then a three-objective optimization is accomplished to specify the optimal design points for the purpose of minimizing the product unit cost and maximizing the exergy coefficient of performance as well as the distilled water mass flow rate. In this regard, the Pareto frontiers are plotted for all the systems. The results show that, under the optimized conditions, the exergy coefficient of performance and distilled water mass flow rate for the proposed configuration can be higher by 16% and 38% with respect to the corresponding values in the other two systems. In addition, it is observed that the maximum gross temperature lift in the proposed system is about 20–40% higher than those in the other systems.

  14. Effluent Storage and Biomat Occurrence among Septic System Absorption Field Architectures in a Typic Fragiudult.

    Science.gov (United States)

    Prater, N J M; Brye, K R; Dunn, S; Soerens, T S; Sharpley, A N; Mason, E; Gbur, E E

    2013-07-01

    On-site wastewater treatment systems (OWTSs) are commonly used by households in areas of low population density to treat household wastewater and recycle it back to the environment. However, new absorption field products of differing architecture types have recently become available. A 3-yr field study was conducted in Bethel Heights, northwest Arkansas to assess several newer architecture types (i.e., chambers, polystyrene-aggregate, and gravel-less pipe) relative to the traditional pipe-and-gravel design under wet- and dry-soil conditions. Thirteen products of four different architecture types were installed in 46-cm-deep trenches in a Captina silt loam (fine-silty, siliceous, active, mesic Typic Fragiudult). Products were evaluated based on in-trench solution storage measured with an electronic water-level sensor approximately weekly from January 2009 through January 2012. Between May 2010 and January 2012, the thickness of any biomat formation was measured approximately weekly by insertion of a wooden dowel through in-trench monitoring ports. Architecture type alone did not affect ( > 0.05) in-trench solution storage. However, solution storage among individual products differed under wet- and dry-soil conditions ( storage but that several alternative products also had greater solution storage than that of the traditional pipe-and-gravel system. With no observed effluent surfacing, the soil morphology approach appears to be adequate and appropriately environmentally conservative for assigning typical single-family loading rates to alternative OWTS products and to the traditional pipe-and-gravel system. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  15. Synthesis of integrated absorption refrigeration systems involving economic and environmental objectives and quantifying social benefits

    International Nuclear Information System (INIS)

    Lira-Barragán, Luis Fernando; Ponce-Ortega, José María; Serna-González, Medardo; El-Halwagi, Mahmoud M.

    2013-01-01

    This paper presents a new methodology for energy integration of systems that require absorption refrigeration. It allows heat exchange among process hot and cold streams and the integration of excess process heat as well as external utilities provided by solar energy, fossil fuels and biofuels. An optimization formulation is developed to address the multiple objectives of simultaneously minimizing the total annualized cost and the greenhouse gas emissions while the social impact is measured by the number of jobs generated by the project in the entire life cycle. The economic function accounts for the tax credit obtained by the reduction of greenhouse gas emissions when cleaner technologies are used. The proposed model also considers the optimal selection of different types of solar collectors and the optimal time-based usage of solar energy, fossil fuel, and biofuel. Two example problems are presented to show the applicability of the proposed methodology. -- Highlights: ► An approach for the thermal integration of refrigeration processes is proposed. ► Different forms of sustainable energies are considered in the optimization process. ► Economic and environmental objectives are considered quantifying the number of jobs. ► The availability for the different forms of energy is taken into account. ► Results show significant advantages obtained with the proposed approach

  16. Hydrogeologic implications of increased septic-tank-soil-absorption system density, Ogden Valley, Weber County, Utah

    Science.gov (United States)

    Lowe, Mike; Miner, Michael L.; ,

    1990-01-01

    Ground water in Ogden Valley occurs in perched, confined, and unconfined aquifers in the valley fill to depths of 600 feet and more. The confined aquifer, which underlies only the western portion of the valley, is overlain by cleyey silt lacustrine sediments probably deposited during the Bonneville Basin's Little Valley lake cycle sometime between 90,000 and 150,000 years ago. The top of this cleyey silt confining layer is generally 25 to 60 feet below the ground surface. Unconfined conditions occur above and beyond the outer margin of the confining layer. The sediments overlying the confining layer are primarily Lake Bonneville deposits. Water samples from springs, streams, and wells around Pineview Reservoir, and from the reservoir itself, were collected and analyzed. These samples indicate that water quality in Ogden Valley is presently good. Average nitrate concentrations in the shallow unconfined aquifer increase toward the center of Ogden Valley. This trend was not observed in the confined aquifer. There is no evidence, however, of significant water-quality deterioration, even in the vicinity of Huntsville, a town that has been densely developed using septic-tank-soil-absorption systems for much of the time since it was founded in 1860.

  17. Resonant two-photon absorption and electromagnetically induced transparency in open ladder-type atomic system.

    Science.gov (United States)

    Moon, Han Seb; Noh, Heung-Ryoul

    2013-03-25

    We have experimentally and theoretically studied resonant two-photon absorption (TPA) and electromagnetically induced transparency (EIT) in the open ladder-type atomic system of the 5S(1/2) (F = 1)-5P(3/2) (F' = 0, 1, 2)-5D(5/2) (F″ = 1, 2, 3) transitions in (87)Rb atoms. As the coupling laser intensity was increased, the resonant TPA was transformed to EIT for the 5S(1/2) (F = 1)-5P(3/2) (F' = 2)-5D(5/2) (F″ = 3) transition. The transformation of resonant TPA into EIT was numerically calculated for various coupling laser intensities, considering all the degenerate magnetic sublevels of the 5S(1/2)-5P(3/2)-5D(5/2) transition. From the numerical results, the crossover from TPA to EIT could be understood by the decomposition of the spectrum into an EIT component owing to the pure two-photon coherence and a TPA component caused by the mixed term.

  18. Solar heating and cooling system with absorption chiller and low temperature latent heat storage: Energetic performance and operational experience

    Energy Technology Data Exchange (ETDEWEB)

    Helm, M.; Keil, C.; Hiebler, S.; Mehling, H.; Schweigler, C. [Bavarian Center for Applied Energy Research (ZAE Bayern) (Germany)

    2009-06-15

    Absorption cooling systems based on water/lithium bromide (LiBr) solution typically require an open wet cooling tower to transfer the reject heat to the ambient. Yet, water consumption, the need for water make-up and cleaning, formation of fog, and the risk of Legionella bacteria growth are hindering factors for the implementation of small solar cooling systems. The application of a latent heat storage supporting the heat rejection of the absorption chiller in conjunction with a dry cooling system allows eliminating the wet cooling tower. By that means heat rejection of the chiller is shifted to periods with lower ambient temperatures, i.e. night time or off-peak hours. The system concept and the hydraulic scheme together with an analysis of the energetic performance of the system are presented, followed by a report on the operation of a first pilot installation. (author)

  19. Application of a solar refrigeration system by absorption for the air conditioning of buildings

    Energy Technology Data Exchange (ETDEWEB)

    Machielsen, Cees H. M [Delft University of Technology, Mekelweg (Netherlands); Hagendijk, Andre E [Consultancy and Research (Netherlands)

    2000-07-01

    This paper describes the Sofri project, a cooperation between Ceeran Ltd and The Delft University of Technology. The main objective of this project is to develop the necessary knowledge and experience to commercialize solar-assisted air conditioning and dehumidification systems in the Dutch Caribbean. The project is motivated by the present needs of the Dutch Caribbean for renewable energy sources and the fact that the Caribbean has a high and uniform insolation throughout the year. Furthermore, hotels and offices in this area use more than 40% of their energy for air-conditioning purposes. Therefore solar-assisted air conditioning systems are a logic approach in reducing the energy demand and to lower the peak electricity reducing the energy demands for the local power station. Ceeran Ltd has the objective to reach full commercialization of the proposed technologies in the Dutch Caribbean. The research is concentrated on liquid absorption machines and solar collection systems such as flat plates with selective surfaces, heat pipe evacuated tubes flat plate collectors, and Compound Parabolic Concentrators. The first demonstration unit is planned to be installed in an office building in Curacao. The installation consists of a 35 kW LiBr/H{sub 2}O absorption machine driven by 100 m{sup 2} flat pate collectors with a gas backup system. The system will provide comfort air-conditioning for this these type of office buildings during daytime. [Spanish] Este documento describe el proyecto SOFRI, una cooperacion entre Ceeran, Ltd, y la Universidad Tecnologica del Delft. El principal objetivo de este proyecto es el de desarrollar el conocimiento necesario y la experiencia para comercializar los sistemas de aire acondicionado y deshumidificacion ayudados por la energia solar en el Caribe Holandes. Este proyecto ha sido motivado por las actuales necesidades del Caribe Holandes de fuentes de energia renovable y por el hecho de que el Caribe tiene una alta y uniforme insolacion

  20. Evaluation of an oral carrier system in rats: bioavailability and gastrointestinal absorption properties of curcumin encapsulated PBCA nanoparticles

    International Nuclear Information System (INIS)

    Sun Min; Zhao Lixia; Guo Chenyu; Cao Fengliang; Chen Huanlei; Zhao Liyan; Tan Qi; Zhu Xiuqing; Zhu Fanping; Ding Tingting; Zhai Yingjie; Zhai Guangxi

    2012-01-01

    A new oral delivery system, polybutylcyanoacrylate nanoparticles (PBCNs), was introduced to improve the oral bioavailability of curcumin (CUR), a poorly soluble drug. The formulation was optimized by orthogonal design and the optimal PBCNs loading CUR exhibited a spherical shape under transmission electron microscopy with a range of 40–400 nm. Physicochemical state of CUR in PBCN was investigated by X-ray diffraction and the possible structure changes occurring in CUR after conjugating with polybutylcyanoacrylate were studied with FTIR. The results indicated that CUR in PBCN was in a non-crystalline state and CUR was encapsulated in PBCN without chemical reaction. The oral pharmacokinetic study was conducted in rats and the relative bioavailability of CUR encapsulated PBCNs to the crude CUR was more than 800%. The in situ absorption experiment in rat intestine indicated the absorption was first order with passive diffusion mechanism. The absorption results in various segments of intestine showed that the main absorption sites were ileum and colon. It can be concluded that PBCNs as an oral carrier can significantly improve the oral absorption of a poorly soluble drug.

  1. Evaluation of an oral carrier system in rats: bioavailability and gastrointestinal absorption properties of curcumin encapsulated PBCA nanoparticles

    Science.gov (United States)

    Sun, Min; Zhao, Lixia; Guo, Chenyu; Cao, Fengliang; Chen, Huanlei; Zhao, Liyan; Tan, Qi; Zhu, Xiuqing; Zhu, Fanping; Ding, Tingting; Zhai, Yingjie; Zhai, Guangxi

    2012-02-01

    A new oral delivery system, polybutylcyanoacrylate nanoparticles (PBCNs), was introduced to improve the oral bioavailability of curcumin (CUR), a poorly soluble drug. The formulation was optimized by orthogonal design and the optimal PBCNs loading CUR exhibited a spherical shape under transmission electron microscopy with a range of 40-400 nm. Physicochemical state of CUR in PBCN was investigated by X-ray diffraction and the possible structure changes occurring in CUR after conjugating with polybutylcyanoacrylate were studied with FTIR. The results indicated that CUR in PBCN was in a non-crystalline state and CUR was encapsulated in PBCN without chemical reaction. The oral pharmacokinetic study was conducted in rats and the relative bioavailability of CUR encapsulated PBCNs to the crude CUR was more than 800%. The in situ absorption experiment in rat intestine indicated the absorption was first order with passive diffusion mechanism. The absorption results in various segments of intestine showed that the main absorption sites were ileum and colon. It can be concluded that PBCNs as an oral carrier can significantly improve the oral absorption of a poorly soluble drug.

  2. Evaluation of an oral carrier system in rats: bioavailability and gastrointestinal absorption properties of curcumin encapsulated PBCA nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Sun Min; Zhao Lixia; Guo Chenyu; Cao Fengliang; Chen Huanlei; Zhao Liyan; Tan Qi; Zhu Xiuqing; Zhu Fanping; Ding Tingting; Zhai Yingjie; Zhai Guangxi, E-mail: professorzhai@yeah.net [Shandong University, Department of Pharmaceutics, College of Pharmacy (China)

    2012-02-15

    A new oral delivery system, polybutylcyanoacrylate nanoparticles (PBCNs), was introduced to improve the oral bioavailability of curcumin (CUR), a poorly soluble drug. The formulation was optimized by orthogonal design and the optimal PBCNs loading CUR exhibited a spherical shape under transmission electron microscopy with a range of 40-400 nm. Physicochemical state of CUR in PBCN was investigated by X-ray diffraction and the possible structure changes occurring in CUR after conjugating with polybutylcyanoacrylate were studied with FTIR. The results indicated that CUR in PBCN was in a non-crystalline state and CUR was encapsulated in PBCN without chemical reaction. The oral pharmacokinetic study was conducted in rats and the relative bioavailability of CUR encapsulated PBCNs to the crude CUR was more than 800%. The in situ absorption experiment in rat intestine indicated the absorption was first order with passive diffusion mechanism. The absorption results in various segments of intestine showed that the main absorption sites were ileum and colon. It can be concluded that PBCNs as an oral carrier can significantly improve the oral absorption of a poorly soluble drug.

  3. The large-scale cross-correlation of Damped Lyman alpha systems with the Lyman alpha forest: first measurements from BOSS

    Energy Technology Data Exchange (ETDEWEB)

    Font-Ribera, Andreu [Institute of Theoretical Physics, University of Zurich, 8057 Zurich (Switzerland); Miralda-Escudé, Jordi [Institució Catalana de Recerca i Estudis Avançats, Barcelona, Catalonia (Spain); Arnau, Eduard [Institut de Ciències del Cosmos (IEEC/UB), Barcelona, Catalonia (Spain); Carithers, Bill; Ross, Nicholas P.; White, Martin [Lawrence Berkeley National Laboratory, University of California Berkeley, Berkeley, California 94720 (United States); Lee, Khee-Gan [Max-Planck-Institut für Astronomie, Königstuhl 17, D-69117, Heidelberg (Germany); Noterdaeme, Pasquier; Pâris, Isabelle; Petitjean, Patrick; Rollinde, Emmanuel [Institut d' Astrophysique de Paris, Université Paris 6 et CNRS, 98bis blvd. Arago, 75014 Paris (France); Rich, James [CEA, Centre de Saclay, IRFU, 91191 Gif-sur-Yvette (France); Schneider, Donald P. [Department of Astronomy and Astrophysics, The Pennsylvania State University, University Park, PA 16802 (United States); York, Donald G., E-mail: font@physik.uzh.ch, E-mail: miralda@icc.ub.edu [Department of Astronomy and Astrophysics and The Fermi Institute, Chicago University, 5640 So. Ellis Ave., Chicago, IL 60637 (United States)

    2012-11-01

    We present the first measurement of the large-scale cross-correlation of Lyα forest absorption and Damped Lyman α systems (DLA), using the 9th Data Release of the Baryon Oscillation Spectroscopic Survey (BOSS). The cross-correlation is clearly detected on scales up to 40h{sup −1}Mpc and is well fitted by the linear theory prediction of the standard Cold Dark Matter model of structure formation with the expected redshift distortions, confirming its origin in the gravitational evolution of structure. The amplitude of the DLA-Lyα cross-correlation depends on only one free parameter, the bias factor of the DLA systems, once the Lyα forest bias factors are known from independent Lyα forest correlation measurements. We measure the DLA bias factor to be b{sub D} = (2.17±0.20)β{sub F}{sup 0.22}, where the Lyα forest redshift distortion parameter β{sub F} is expected to be above unity. This bias factor implies a typical host halo mass for DLAs that is much larger than expected in present DLA models, and is reproduced if the DLA cross section scales with halo mass as M{sub h}{sup α}, with α = 1.1±0.1 for β{sub F} = 1. Matching the observed DLA bias factor and rate of incidence requires that atomic gas remains extended in massive halos over larger areas than predicted in present simulations of galaxy formation, with typical DLA proper sizes larger than 20 kpc in host halos of masses ∼ 10{sup 12}M{sub ☉}. We infer that typical galaxies at z ≅ 2 to 3 are surrounded by systems of atomic clouds that are much more extended than the luminous parts of galaxies and contain ∼ 10% of the baryons in the host halo.

  4. Study of absorption and re-emission processes in a ternary liquid scintillation system

    International Nuclear Information System (INIS)

    Xiao Hualin; Wang Naiyan; Li Xiaobo; Cao Jun; Wen Liangjian; Zheng Dong

    2010-01-01

    Liquid scintillators are widely used as the neutrino target in neutrino experiments. The absorption and emission of different components of a ternary liquid scintillator (Linear Alkyl Benzene (LAB) as the solvent, 2, 5-diphenyloxazole (PPO) as the fluor and p-bis-(o-methylstyryl)-benzene (bis-MSB) as wavelength shifter) are studied. It is shown that the absorption of this liquid scintillator is dominant by LAB and PPO at wavelengths less than 349 nm, and the absorption by bis-MSB becomes prevalent at the wavelength larger than 349 nm. The fluorescence quantum yields, which are the key parameters to model the absorption and re-emission processes in large liquid scintillation detectors, are measured. (authors)

  5. [Engineering of a System for the Production of Mutant Human Alpha-Fetoprotein in the Methylotrophic Yeast Pichia pastoris].

    Science.gov (United States)

    Morozkina, E V; Vavilova, E A; Zatsepin, S S; Klyachko, E V; Yagudin, T A; Chulkin, A M; Dudich, I V; Semenkova, L N; Churilova, I V; Benevolenskii, S V

    2016-01-01

    A system for the production of mutant recombinant human alpha-fetoprotein (rhAFPO) lacking the glycosylation site has been engineered in the yeast Pichia pastoris. A strain of the methylotrophic yeast Pichia pastoris GS 115/pPICZ?A/rhAFP0, which produces unglycosylated rhAFPO and secretes it to the culture medium, has been constructed. Optimization and scale-up of the fermentation technology have resulted in an increase in the rhAFP0 yield to 20 mg/L. A scheme of isolation and purification of biologically active rhAFP0 has been developed. The synthesized protein has the antitumor activity, which is analogous to the activity of natural human embryonic alpha-fetoprotein.

  6. Optimal design of solid oxide fuel cell, ammonia-water single effect absorption cycle and Rankine steam cycle hybrid system

    Science.gov (United States)

    Mehrpooya, Mehdi; Dehghani, Hossein; Ali Moosavian, S. M.

    2016-02-01

    A combined system containing solid oxide fuel cell-gas turbine power plant, Rankine steam cycle and ammonia-water absorption refrigeration system is introduced and analyzed. In this process, power, heat and cooling are produced. Energy and exergy analyses along with the economic factors are used to distinguish optimum operating point of the system. The developed electrochemical model of the fuel cell is validated with experimental results. Thermodynamic package and main parameters of the absorption refrigeration system are validated. The power output of the system is 500 kW. An optimization problem is defined in order to finding the optimal operating point. Decision variables are current density, temperature of the exhaust gases from the boiler, steam turbine pressure (high and medium), generator temperature and consumed cooling water. Results indicate that electrical efficiency of the combined system is 62.4% (LHV). Produced refrigeration (at -10 °C) and heat recovery are 101 kW and 22.1 kW respectively. Investment cost for the combined system (without absorption cycle) is about 2917 kW-1.

  7. Determination of specific alpha-radioactivity of flora samples from semipalatinsk test site (STS)

    International Nuclear Information System (INIS)

    Blekhman, A.M.; Dujsenbaev, A.; Orazova, A.O.

    1999-01-01

    For further rehabilitation of soil earlier contaminated with radioactive fallout, the method of radionuclide absorption by plants is vital. The last updating of electronic system of the facility meant to analyze impulse shape /2/ helped to enlarge dynamical range of registration and reduction of identification threshold for alpha particles up to 50 keV. We have developed methods for STS flora samples preparation and performed first measurements of their specific alpha activity. Measurement results are in table 1. Measurement results analysis shows that STS flora samples can accumulate considerable concentrations of alpha active nuclides

  8. Characterization Of The Alpha/Beta Counting System Type MPC 9400 And Its Utilization

    International Nuclear Information System (INIS)

    Makhsum; Sutarman; Fikri, Hanif; Handoko, Djati

    2000-01-01

    Have been carried out the experiment to determine the operation voltage, instrument stability, counting efficiency, figure of merit, and minimum detectable activity. This instrument used to count gross alpha and gross beta. This instrument belongs good stability at the confidence level of 95 % and the background count that was 0,144 cpm for alpha and 22,65 cpm for beta. The counting efficiency was 27,41 % (electrodeposition of Am-241), 6,57 % (deposition of Am-241), 51,82 % (deposition of Sr-90). The limit of detectable activity was 1,04 x 10 exp.-2 Bq (electrodeposition of Am-241), 4,35 x 10 exp.-2 Bq (% deposition of Sr 90)

  9. Buffett's Alpha

    DEFF Research Database (Denmark)

    Frazzini, Andrea; Kabiller, David; Heje Pedersen, Lasse

    Berkshire Hathaway has realized a Sharpe ratio of 0.76, higher than any other stock or mutual fund with a history of more than 30 years, and Berkshire has a significant alpha to traditional risk factors. However, we find that the alpha becomes insignificant when controlling for exposures to Betting...

  10. Alpha Blockers

    Science.gov (United States)

    ... quickly, but their effects last only a few hours. Long-acting medications take longer to work, but their effects last longer. Which alpha blocker is best for you depends on your health and the condition being treated. Alpha blockers are ...

  11. Source preparations for alpha and beta measurements

    Energy Technology Data Exchange (ETDEWEB)

    Holm, E. [Risoe National Lab., Roskilde (Denmark)

    2001-01-01

    Regarding alpha particle emitters subject for environmental studies, electrodeposition or co-precipitation as fluorides are the most common methods. For electro deposition stainless steel is generally used as cathode material but also other metals such as Ni, Ag, and Cu showed promising results. The use of other anode material than platinum, such as graphite should be investigated. For other purposes such as optimal resolution other more sophisticated methods are used but often resulting in poorer recovery. For beta particle emitters the type of detection system will decide the source preparation. Similar methods as for alpha particle emitters, electrodeposition or precipitation techniques can be used. Due to the continuous energy distribution of the beta pulse height distribution a high resolution is not required. Thicker sources from the precipitates or a stable isotopic carrier can be accepted but correction for absorption in the source must be done. (au)

  12. Angular distributions of the alpha particle production in the 7Li+144Sm system at near-barrier energies

    International Nuclear Information System (INIS)

    Carnelli, P F F; Arazi, A; Capurro, O A; Niello, J O Fernández; Heimann, D Martinez; Pacheco, A J; Cardona, M A; De Barbará, E; Figueira, J M; Hojman, D L; Martí, G V; Negri, A E

    2015-01-01

    We have studied the production of alpha particles in reactions induced by 7 Li projectiles on a 144 Sm target at bombarding energies of 18, 24 and 30 MeV over the 15°-140° angular range. The purpose of the investigation has been to determine the contribution of different mechanisms in reactions that involve weakly bound projectiles. We have included in our analysis several processes that can either directly or sequentially lead to the emission of alpha particles: complete fusion, direct transfer of 3 H, capture breakup (incomplete fusion, sequential complete fusion) and non-capture breakup. In order to distinguish alpha particles stemming from these processes it is necessary to determine the mass and charge of the reaction products and to obtain precise measurements of their energies and scattering angles over relatively wide ranges of these variables. We have done this using a detection system consisting of an ionization chamber plus three position sensitive detectors. We present results of these measurements and a preliminary interpretation based on kinematical considerations and comparisons with predictions from a statistical model. (paper)

  13. Performance assessment of geological isolation systems for medium and alpha waste disposal in granitic formations

    International Nuclear Information System (INIS)

    Lewi, J.; Brun-Yaba, C.; Cernes, A.

    1990-01-01

    PACOMA (Performance Assessment of Confinement for Medium and Alpha Waste) is a coordinated project of the Commission of the European Communities with the participation of the Member States. This project is intended to evaluate the suitability of clay, granite and salt formations to dispose of conditioned alpha and medium-level radioactive waste. In this report, CEA-IPSN presents the database and the results of evaluating the radiological consequences associated to the disposal of alpha-bearing waste in a deep granite formation. Two repository concepts and three sites have been examined (Auriat, a hypothetical site in the UK and Barfleur) which are identical to those considered in the PAGIS project. The methodology adopted for the PAGIS project has been used for carrying out the deterministic calculations of radiological consequences in the case of normal evolution scenarios and in altered evolutions, as well as for sensitivity analysis of results to the calculation parameters and for uncertainty studies. The calculation of individual doses in the case of normal evolutions show, after a first peak due to I-129, Se-79 and Tc-99 some hundred of thousands years, a maximum, which is reached only after several million of years. In all cases, these maxima are largely lower (by a factor of 1000 at least), than the limit recommended by the IRCP

  14. Determining CDOM Absorption Spectra in Diverse Coastal Environments Using a Multiple Pathlength, Liquid Core Waveguide System. Measuring the Absorption of CDOM in the Field Using a Multiple Pathlength Liquid Waveguide System

    Science.gov (United States)

    Miller, Richard L.; Belz, Mathias; DelCastillo, Carlos; Trzaska, Rick

    2000-01-01

    We evaluated the accuracy, sensitivity and precision of a multiple pathlength, liquid core waveguide (MPLCW) system for measuring colored dissolved organic matter (CDOM) absorption in the UV-visible spectral range (370-700 nm). The MPLCW has four optical paths (2.0, 9.8, 49.3, and 204 cm) coupled to a single Teflon AF sample cell. Water samples were obtained from inland, coastal and ocean waters ranging in salinity from 0 to 36 PSU. Reference solutions for the MPLCW were made having a refractive index of the sample. CDOM absorption coefficients, a(sub CDOM), and the slope of the log-linearized absorption spectra, S, were compared with values obtained using a dual-beam spectrophotometer. Absorption of phenol red secondary standards measured by the MPLCW at 558 nm were highly correlated with spectrophotometer values (r > 0.99) and showed a linear response across all four pathlengths. Values of a(sub CDOM) measured using the MPLCW were virtually identical to spectrophotometer values over a wide range of concentrations. The dynamic range of a(sub CDOM) for MPLCW measurements was 0.002 - 231.5/m. At low CDOM concentrations (a(sub 370) CDOM) were slightly greater than MPLCW values and showed larger fluctuations at longer wavelengths due to limitations in instrument precision. In contrast, MPLCW spectra followed an exponential to 600 nm for all samples. The maximum deviation in replicate MPLCW spectra was less than 0.001 absorbance units. The portability, sampling, and optical characteristics of a MPLCW system provide significant enhancements for routine CDOM absorption measurements in a broad range of natural waters.

  15. X ray absorption fine structure of systems in the anharmonic limit

    Science.gov (United States)

    Mustredeleon, J.; Conradson, S. D.; Batistic, I.; Bishop, A. R.; Raistrick, I.; Jackson, W. E.; Brown, G. E.

    A new approach to the analysis of x-ray absorption fine structure (XAFS) data is presented. It is based on the use of radial distribution functions directly calculated from a single-particle ion Hamiltonian containing model potentials. The starting point of this approach is the statistical average of the XAFS for an atomic pair. This average can be computed using a radial distribution function (RDF), which can be expressed in terms of the eigenvalues and wavefunctions associated with the model potential. The pair potential describing the ionic motion is then expressed in terms of parameters that are determined by fitting this statistical average to the experimental XAFS spectrum. This approach allows the use of XAFS as a tool for mapping near-neighbor interatomic potentials, and allows the treatment of systems which exhibit strongly anharmonic potentials which can be treated by perturbative methods. Using this method we have analyzed the high temperature behavior of the oxygen contributions to the Fe K-edge XAFS in the ferrosilicate minerals andradite (Ca3Fe2Si3O12) and magnesiowustite (Mg(0.9)Fe(0.1)O). Using a temperature dependent anharmonic correction derived from these model compounds, we have found evidence for a local structural change in the Fe-O coordination environment upon melting of the geologically important mineral fayalite (Fe2SiO4). We have also employed this method to the study of the axial oxygen contributions to the polarized Cu K-edge XAFS on oriented samples of YBa2Cu3O7 and related compounds. From this study we find evidence for an axial oxygen-centered lattice distortion accompanying the superconducting phase transition and a correlation between this distortion and Tc. The relation of the observed lattice distortion to mechanisms of superconductivity is discussed.

  16. Tamsulosin oral controlled absorption system (OCAS in the treatment of benign prostatic hypertrophy

    Directory of Open Access Journals (Sweden)

    Mischel G Neill

    2008-03-01

    Full Text Available Mischel G Neill, Rohan Shahani, Alexandre R ZlottaDivision of Urology, Department of Surgical Oncology, Princess Margaret and Mount Sinai Hospitals, University of Toronto, Toronto, CanadaAbstract: The efficacy of tamsulosin at the cost of a relatively benign side effect profile has been attributed to receptor selectivity directed at the α1a and α1d adrenergic receptor subtypes. The oral-controlled absorption system (OCAS® represents a drug delivery refinement that incorporates a matrix of gel-forming and gel-enhancing agents to promote a constant drug release independent of environmental food or fluid. There are clinical data to support the concept that drug peaks are lessened and that drug release continues throughout the alimentary tract due to the OCAS formulation. Furthermore this equates with less adverse effects on physiologic parameters. To date however improvements in cardiovascular symptoms such as dizziness, headache and syncope have not been demonstrated in healthy men. Ejaculatory dysfunction appears less problematic with the OCAS preparation. Tamsulosin OCAS may be of greatest benefit to men with cardiovascular co-morbidities taking anti-hypertensive medications that might predispose them to symptomatic hypotensive episodes. It will be necessary to evaluate this group of men more closely in further trials to determine what they stand to gain from changing medications, and then relate this to drug costs to draw a final conclusion as to the place of tamsulosin OCAS in contemporary urological practice.Keywords: lower urinary tract symptoms, benign prostatic hyperplasia, tamsulosin OCAS, safety, efficacy, tolerability

  17. X-ray absorption fine structure of systems in the anharmonic limit

    International Nuclear Information System (INIS)

    Mustre de Leon, J.; Conradson, S.D.; Batistic, I.; Bishop, A.R.; Raistrick, I.; Jackson, W.E.; Brown, G.E.

    1991-01-01

    A new approach to the analysis of x-ray absorption fine structure (XAFS) data is presented. It is based on the use of radial distribution functions directly calculated from a single-particle ion hamiltonian containing model potentials. The starting point of this approach is the statistical average of the XAFS for an atomic pair. This average can be computed using a radial distribution function (RDF), which can be expressed in terms of the eigenvalues and wavefunctions associated with the model potential. The pair potential describing the ionic motion is then expressed in terms of parameters that are determined by fitting this statistical average to the experimental XAFS spectrum. This approach allow the use of XAFS as a tool for mapping near-neighbor interatomic potentials, and allows the treatment of systems which exhibit strongly anharmonic potentials which can be treated by perturbative methods. Using this method we have analyzed the high temperature behavior of the oxygen contributions to the Fe K-edge XAFS in the ferrosilicate minerals andradite (Ca 3 Fe 2 Si 3 O 12 ) and magnesiowustite (Mg 0.9 Fe 0.1 O). Using a temperature dependent anharmonic correction derived from these model compounds, we have found evidence for a local structural change in the Fe-O coordination environment upon melting of the geologically important mineral fayalite (Fe 2 SiO 4 ). We have also employed this method to the study of the axial oxygen contributions to the polarized Cu K-edge XAFS on oriented samples of YBa 2 Cu 3 O 7 and related compounds. From this study we find evidence for an axial oxygen-centered lattice distortion accompanying the superconducting phase transition and a correlation between this distortion and T c . The relation of the observed lattice distortion to mechanisms of superconductivity is discussed. 33 refs., 6 figs

  18. Effect of the hardener to epoxy monomer ratio on the water absorption behavior of the DGEBA/TETA epoxy system

    Directory of Open Access Journals (Sweden)

    Ayrton Alef Castanheira Pereira

    2016-02-01

    Full Text Available Abstract The water absorption behavior of the DGEBA/TETA epoxy system was evaluated as a function of the epoxy monomer to amine hardener ratio. Weight gain versus immersion time curves were obtained and the experimental points were fitted using Fickian and Non-Fickian diffusion models. The results obtained showed that for all epoxy monomer to hardener ratios analyzed water diffusion followed non-Fickian behavior. It was possible to correlate the water absorption behavior to the macromolecular structure developed when the epoxy/ hardener ratio was varied. All epoxy/hardener ratios present a two-phase macromolecular structure, composed of regions with high crosslink density and regions with lower crosslinking. Epoxy rich systems have a more open macromolecular structure with a lower fraction of the dense phase than the amine rich systems, which present a more compact two-phase structure.

  19. Measured performance of a 3 ton LiBr absorption water chiller and its effect on cooling system operation

    Science.gov (United States)

    Namkoong, D.

    1976-01-01

    A three ton lithium bromide absorption water chiller was tested for a number of conditions involving hot water input, chilled water, and the cooling water. The primary influences on chiller capacity were the hot water inlet temperature and the cooling water inlet temperature. One combination of these two parameters extended the output to as much as 125% of design capacity, but no combination could lower the capacity to below 60% of design. A cooling system was conceptually designed so that it could provide several modes of operation. Such flexibility is needed for any solar cooling system to be able to accommodate the varying solar energy collection and the varying building demand. It was concluded that a three-ton absorption water chiller with the kind of performance that was measured can be incorporated into a cooling system such as that proposed, to provide efficient cooling over the specified ranges of operating conditions.

  20. Measured performance of a 3-ton LiBr absorption water chiller and its effect on cooling system operation

    Science.gov (United States)

    Namkoong, D.

    1976-01-01

    A 3-ton lithium bromide absorption water chiller was tested for a number of conditions involving hot-water input, chilled water, and the cooling water. The primary influences on chiller capacity were the hot water inlet temperature and the cooling water inlet temperature. One combination of these two parameters extended the output to as much as 125% of design capacity, but no combination could lower the capacity to below 60% of design. A cooling system was conceptually designed so that it could provide several modes of operation. Such flexibility is needed for any solar cooling system to be able to accommodate the varying solar energy collection and the varying building demand. It is concluded that a 3-ton absorption water chiller with the kind of performance that was measured can be incorporated into a cooling system such as that proposed, to provide efficient cooling over the specified ranges of operating conditions.

  1. Analysis of hybrid membrane and chemical absorption systems for CO2 capture

    International Nuclear Information System (INIS)

    Binns, Michael; Oh, Se-Young; Kwak, Dong-Hun; Kim, Jin-Kuk

    2015-01-01

    Amine-based absorption of CO 2 is currently the industry standard technology for capturing CO 2 emitted from power plants, refineries and other large chemical plants. However, more recently there have been a number of competing technologies under consideration, including the use of membranes for CO 2 separation and purification. We constructed and analyzed two different hybrid configurations combining and connecting chemical absorption with membrane separation. For a particular flue gas which is currently treated with amine-based chemical absorption at a pilot plant we considered and tested how membranes could be integrated to improve the performance of the CO 2 capture. In particular we looked at the CO 2 removal efficiency and the energy requirements. Sensitivity analysis was performed varying the size of the membranes and the solvent flow rate

  2. Solar hybrid cooling system for high-tech offices in subtropical climate - Radiant cooling by absorption refrigeration and desiccant dehumidification

    International Nuclear Information System (INIS)

    Fong, K.F.; Chow, T.T.; Lee, C.K.; Lin, Z.; Chan, L.S.

    2011-01-01

    Highlights: → A solar hybrid cooling system is proposed for high-tech offices in subtropical climate. → An integration of radiant cooling, absorption refrigeration and desiccant dehumidification. → Year-round cooling and energy performances were evaluated through dynamic simulation. → Its annual primary energy consumption was lower than conventional system up to 36.5%. → The passive chilled beams were more energy-efficient than the active chilled beams. - Abstract: A solar hybrid cooling design is proposed for high cooling load demand in hot and humid climate. For the typical building cooling load, the system can handle the zone cooling load (mainly sensible) by radiant cooling with the chilled water from absorption refrigeration, while the ventilation load (largely latent) by desiccant dehumidification. This hybrid system utilizes solar energy for driving the absorption chiller and regenerating the desiccant wheel. Since a high chilled water temperature generated from the absorption chiller is not effective to handle the required latent load, desiccant dehumidification is therefore involved. It is an integration of radiant cooling, absorption refrigeration and desiccant dehumidification, which are powered up by solar energy. In this study, the application potential of the solar hybrid cooling system was evaluated for the high-tech offices in the subtropical climate through dynamic simulation. The high-tech offices are featured with relatively high internal sensible heat gains due to the intensive office electric equipment. The key performance indicators included the solar fraction and the primary energy consumption. Comparative study was also carried out for the solar hybrid cooling system using two common types of chilled ceilings, the passive chilled beams and active chilled beams. It was found that the solar hybrid cooling system was technically feasible for the applications of relatively higher cooling load demand. The annual primary energy

  3. Mini-DIAL system measurements coupled with multivariate data analysis to identify TIC and TIM simulants: preliminary absorption database analysis

    International Nuclear Information System (INIS)

    Gaudio, P; Malizia, A; Gelfusa, M; Poggi, L.A.; Martinelli, E.; Di Natale, C.; Bellecci, C.

    2017-01-01

    Nowadays Toxic Industrial Components (TICs) and Toxic Industrial Materials (TIMs) are one of the most dangerous and diffuse vehicle of contamination in urban and industrial areas. The academic world together with the industrial and military one are working on innovative solutions to monitor the diffusion in atmosphere of such pollutants. In this phase the most common commercial sensors are based on “point detection” technology but it is clear that such instruments cannot satisfy the needs of the smart cities. The new challenge is developing stand-off systems to continuously monitor the atmosphere. Quantum Electronics and Plasma Physics (QEP) research group has a long experience in laser system development and has built two demonstrators based on DIAL (Differential Absorption of Light) technology could be able to identify chemical agents in atmosphere. In this work the authors will present one of those DIAL system, the miniaturized one, together with the preliminary results of an experimental campaign conducted on TICs and TIMs simulants in cell with aim of use the absorption database for the further atmospheric an analysis using the same DIAL system. The experimental results are analysed with standard multivariate data analysis technique as Principal Component Analysis (PCA) to develop a classification model aimed at identifying organic chemical compound in atmosphere. The preliminary results of absorption coefficients of some chemical compound are shown together pre PCA analysis. (paper)

  4. Development of sound absorption measuring system with acoustic chamber; Kogata kyuon koka sokutei sochi no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Takahira, M.; Noba, M. [Toyota Motor Corp., Aichi (Japan); Matsuoka, H. [Nippon Soken, Inc., Tokyo (Japan)

    1998-05-01

    In order to measure sound absorption performance necessary to develop sound absorption materials, development was made on a device consisting of a small sound box capable of measurement inexpensively and easily, as a measure against the reverberation chamber method. In order to obtain stabilized diffusion sound internally, the sound box has a shape of asymmetric seven-side body in which sides do not face squarely with each other. The box was so sized that a large number of resonant vibration postures can be constituted at the targeted frequency simultaneously in the box. The box has a commercially available cone speaker with good acoustic output characteristics in frequency range of higher than 500 Hz installed on an inner side of the box. The sound source uses a method to derive sound absorption rate from difference of sound pressure levels. In order to eliminate need of averaging treatment by using a multi-point measurement inside the box, a discussion was given to provide an opening on part of the box to place the sound receiving point outside the opening. A square test piece is placed on the floor 0.5 meter or more away from the speaker in the box. As a result of the experiment, it was verified that the sound absorption rate obtained by this device corresponds well with that by the reverberation chamber method. The size of the test piece was also found adequate. 2 refs., 11 figs., 1 tab.

  5. High Pressure X-ray Absorption Studies on Correlated-Electron Systems

    International Nuclear Information System (INIS)

    Cornelius, Andrew L.

    2016-01-01

    This project used high pressure to alter the electron-electron and electron-lattice interactions in rare earth and actinide compounds. Knowledge of these properties is the starting points for a first-principles understanding of electronic and electronically related macroscopic properties. The research focused on a systematic study of x-ray absorption measurements on rare earth and actinide compounds.

  6. The effects of the alpha2-adrenergic receptor agonists clonidine and rilmenidine, and antagonists yohimbine and efaroxan, on the spinal cholinergic receptor system in the rat

    DEFF Research Database (Denmark)

    Abelson, Klas S P; Höglund, A Urban

    2004-01-01

    Cholinergic agonists produce spinal antinociception via mechanisms involving an increased release of intraspinal acetylcholine. The cholinergic receptor system interacts with several other receptor types, such as alpha2-adrenergic receptors. To fully understand these interactions, the effects...... of various receptor ligands on the cholinergic system must be investigated in detail. This study was initiated to investigate the effects of the alpha2-adrenergic receptor agonists clonidine and rilmenidine and the alpha2-adrenergic receptor antagonists yohimbine and efaroxan on spinal cholinergic receptors......, all ligands possessed affinity for nicotinic receptors. Clonidine and yohimbine binding was best fit to a one site binding curve and rilmenidine and efaroxan to a two site binding curve. The present study demonstrates that the tested alpha2-adrenergic receptor ligands affect intraspinal acetylcholine...

  7. cap alpha. -bungarotoxin binding properties of a central nervous system nicotinic acetylcholine receptor

    Energy Technology Data Exchange (ETDEWEB)

    Lukasiewicz, R J; Bennett, E L

    1978-01-01

    High-affinity, specific binding of radiolabeled ..cap alpha..-bungarotoxin to particulate fractions derived from rat brain shows saturability (B/sub max/ approx. = 37fmol/mg, K/sub D//sup app/ = 1.7 nM) and insensitivity to ionic strength, and is essentially irreversible (K/sub on/ = 5 x 10/sup 6/ min/sup -1/ x mol/sup -1/; K(displacement) = 1.9 x 10/sup -4/ min/sup -1/, tau/sub 1/2/ = 62 h). Subcellular distribution of specific sites is consistent with their location on synaptic junctional complex and post-synaptic membranes. These membrane-bound binding sites exhibit unique sensitivity to cholinergic ligands; pretreatment of membranes with cholinergic agonists (but not antagonists) induces transformation of ..cap alpha..-bungarotoxin binding sites to a high affinity form toward agonist. The effect is most marked for the natural agonist, acetylcholine. These results strongly support the notion that the entity under study is an authentic nicotinic acetylcholine receptor.

  8. Synthesis of Hα absorption in old stellar systems: formation of the cluster red sequence by `downsizing'

    Science.gov (United States)

    Smith, Russell J.

    2005-05-01

    We compute population synthesis models for the variation of Hα absorption indices (HαA and HαF), as a function of age and metallicity in old stellar systems. The models are based on the STELIB spectral library of Le Borgne et al., and defined at a resolution of 3Åfull width at half-maximum. Errors in the age and metallicity responses are derived by bootstrap resampling the input measurements on the stellar library. The indices are found to be highly sensitive to age variation, with only moderate response to metallicity. For galaxies uncontaminated by nebular emission, our HαA index is more powerful in breaking the age-metallicity degeneracy than Hβ or HγF. Using a sample of red cluster galaxies from Nelan et al., carefully selected to exclude objects with emission, we find a steep decline of HαA with velocity dispersion (slope -0.75 +/- 0.07Ådex-1). The slope can be translated to constraints on age and metallicity scaling relations, incorporating measurement errors and also the model errors determined from the bootstrap method. If the HαA-σ slope is due only to age, we obtain Age ~σ0.95+/-0.12. Because HαA depends quite weakly on [Fe/H], a metallicity interpretation would require Fe/H ~σ1.2 or steeper. The HαA-σ slope is consistent with the combined age and metallicity scaling relations reported by Nelan et al. from classical Lick indices. The relations obtained by Thomas et al. significantly underpredict the observed slope. The discrepancy could arise from differences in the sample selection. In particular, our sample probes a lower mass range, is not explicitly selected on morphological criteria, and excludes objects significantly bluer than the red sequence. We discuss in detail the impact of emission contamination on the results, and conclude that this effect is unlikely to yield the observed behaviour in the Hα-σ relations. Indeed, similar results are obtained using HαF, despite its different sensitivity to Hα and [NII] emission lines. The

  9. Development and operation of a real-time data acquisition system for the NASA-LaRC differential absorption lidar

    Science.gov (United States)

    Butler, C.

    1985-01-01

    Computer hardware and software of the NASA multipurpose differential absorption lidar (DIAL) sysatem were improved. The NASA DIAL system is undergoing development and experimental deployment for remote measurement of atmospheric trace gas concentration from ground and aircraft platforms. A viable DIAL system was developed with the capability of remotely measuring O3 and H2O concentrations from an aircraft platform. Test flights were successfully performed on board the NASA/Goddard Flight Center Electra aircraft from 1980 to 1984. Improvements on the DIAL data acquisition system (DAS) are described.

  10. Systemic absorption and adverse ocular and systemic effects after topical ophthalmic administration of 0.1% diclofenac to healthy cats.

    Science.gov (United States)

    Hsu, Kimberly K; Pinard, Chantale L; Johnson, Ron J; Allen, Dana G; KuKanich, Butch K; Nykamp, Stephanie G

    2015-03-01

    To quantify plasma concentrations and determine adverse ocular, renal, or hepatic effects associated with repeated topical ophthalmic application of 0.1% diclofenac to healthy cats. 8 healthy sexually intact male cats. A randomized, placebo-controlled crossover study was conducted. A topical formulation of 0.1% diclofenac was administered 4 times/d for 7 days to 4 cats, and artificial tear (control) solution was administered to the other 4 cats. After a 12-day washout period, cats received the other treatment. Ophthalmic examinations were performed daily. Plasma samples were obtained on days 1 and 7 for pharmacokinetic analysis. A CBC, serum biochemical analysis, urinalysis, determination of urine protein-to-creatinine ratio, and determination of glomerular filtration rate were performed before the start of the study and after each 7-day treatment period. Mild conjunctival hyperemia was the only adverse ocular effect detected. Maximal drug concentration and area under the curve were significantly higher on day 7 than on day 1. Diclofenac-treated cats had a significantly lower glomerular filtration rate than did control-treated cats after the second but not after the first treatment period, presumably associated with iatrogenic hypovolemia. Topical ophthalmic administration of 0.1% diclofenac was well tolerated in healthy cats, with only mild signs of ocular irritation. Detectable systemic concentrations of diclofenac were achieved with accumulation over 7 days. Systemic absorption of diclofenac may be associated with reduced glomerular filtration rate, particularly in volume-contracted animals. Topical ophthalmic 0.1% diclofenac should be used with caution in volume-contracted or systemically ill cats.

  11. Thermodynamic analysis of an absorption refrigeration system used to cool down the intake air in an Internal Combustion Engine

    International Nuclear Information System (INIS)

    Novella, R.; Dolz, V.; Martín, J.; Royo-Pascual, L.

    2017-01-01

    Highlights: • Enough power in the exhaust gases is available to operate the absorption cycle. • Three engine operating points are presented in the article. • Improvement potential up to 4% is possible in the engine indicated efficiency. • Engine indicated efficiency benefit was experimentally confirmed by direct testing. - Abstract: This paper deals with the thermodynamic analysis of an absorption refrigeration cycle used to cool down the temperature of the intake air in an Internal Combustion Engine using as a heat source the exhaust gas of the engine. The solution of ammonia-water has been selected due to the stability for a wide range of operating temperatures and pressures and the low freezing point. The effects of operating temperatures, pressures, concentrations of strong and weak solutions in the absorption refrigeration cycle were examined to achieve proper heat rejection to the ambient. Potential of increasing Internal Combustion Engine efficiency and reduce pollutant emissions was estimated by means of theoretical models and experimental tests. In order to provide boundary conditions for the absorption refrigeration cycle and to simulate its effect on engine performance, a 0D thermodynamic model was used to reproduce the engine performance when the intake air is cooled. Furthermore, a detailed experimental work was carried out to validate the results in real engine operation. Theoretical results show how the absorption refrigeration system decreases the intake air flow temperature down to a temperature around 5 °C and even lower by using the bottoming waste heat energy available in the exhaust gases in a wide range of engine operating conditions. In addition, the theoretical analysis estimates the potential of the strategy for increasing the engine indicated efficiency in levels up to 4% also at the operating conditions under evaluation. Finally, this predicted benefit in engine indicated efficiency has been experimentally confirmed by direct

  12. Liquid scintillation alpha spectrometry techniques

    International Nuclear Information System (INIS)

    McKlveen, J.W.; McDowell, W.J.

    1984-01-01

    Accurate, quantitative determinations of alpha emitting nuclides by conventional plate counting methods are difficult, because of sample self-absorption problems in counting and because of non-reproducible losses in conventional sample separation methods. Liquid scintillation alpha spectrometry offers an attractive alternative with no sample self-absorption or geometry problems and with 100% counting efficiency. Sample preparation may include extraction of the alpha emitter of interest by a specific organic phase-soluble compound directly into the liquid scintillation counting medium. Detection electronics use energy and pulse-shape discrimination, to yield alpha spectra without beta and gamma background interference. Specific procedures have been developed for gross alpha, uranium, plutonium, thorium and colonium assay. Possibilities for a large number of other applications exist. Accuracy and reproducibility are typically in the 1% range. Backgrounds of the order of 0.01 cpm are readily achievable. The paper will present an overview of liquid scintillation alpha counting techniques and some of the results achieved for specific applications. (orig.)

  13. Absorption heat pumps

    International Nuclear Information System (INIS)

    Formigoni, C.

    1998-01-01

    A brief description of the difference between a compression and an absorption heat pump is made, and the reasons why absorption systems have spread lately are given. Studies and projects recently started in the field of absorption heat pumps, as well as criteria usually followed in project development are described. An outline (performance targets, basic components) of a project on a water/air absorption heat pump, running on natural gas or LPG, is given. The project was developed by the Robur Group as an evolution of a water absorption refrigerator operating with a water/ammonia solution, which has been on the market for a long time and recently innovated. Finally, a list of the main energy and cost advantages deriving from the use of absorption heat pumps is made [it

  14. Cosmic Metal Production and the Contribution of QSO Absorption Systems to the Ionizing Background

    Science.gov (United States)

    Madau, Piero; Shull, J. Michael

    1996-01-01

    The recent discovery by Cowie et al. (1995) and Tytler et al. (1995) of metals in the Ly alpha clouds shows that the intergalactic medium (IGM) at high redshift is contaminated by the products of stars and suggests that ionizing photons from massive star formation may be a significant contributor to the UV background radiation at early epochs. We assess the validity of the stellar photoionization hypothesis. Based on recent computations of metal yields and 0-star Lyman continuum (Lyc) fluxes, we find that 0.2 percent of the rest-mass energy of the metals produced is radiated as Lyc. By modeling the transfer of ionizing radiation through the IGM and the rate of chemical enrichment, we demonstrate that the background intensity of photons at 1 ryd that accompanies the production of metals in the Ly alpha forest clouds may be significant, approaching 0.5 x 10(exp -21) ergs cm squared s(-1) Hz(-1) sr(-1) at z approximately equals 3 if the Lyc escape fraction is greater than of equal to 0.25. Together with quasars, massive stars could then, in principle, provide the hydrogen and helium Lyc photons required to ionize the universe at high redshifts. We propose that observations of the He2 Gunn-Peterson effect and of the metal ionization states of the Ly alpha forest and Lyman-limit absorbers should show the signature of a stellar spectrum. We also note that the stellar photoionization model fails if a large fraction of the UV radiation emitted from stars cannot escape into the IGM, as suggested by the recent Hopkins Ultraviolet Telescope observations by Leitherer et al. (1995) of low-redshift starburst galaxies, or if most of the metals observed at z is approximately 3 were produced at much earlier epochs.

  15. Contribution to analytical theory of neutron resonance absorption in heterogeneous reactor systems with cylindrical geometry

    International Nuclear Information System (INIS)

    Slipicevic, K.

    1968-12-01

    Following a review of the existing theories od resonance absorption this thesis includes a new approach for calculating the effective resonance integral of absorbed neutrons, new approximate formula for the penetration factor, an analysis of the effective resonance integral and the correction of the resonance integral taking into account the interference of potential and resonance dissipation. A separate chapter is devoted to calculation of the effective resonance integral for the regular reactor lattice with cylindrical fuel elements

  16. Förster resonance energy transfer, absorption and emission spectra in multichromophoric systems. III. Exact stochastic path integral evaluation.

    Science.gov (United States)

    Moix, Jeremy M; Ma, Jian; Cao, Jianshu

    2015-03-07

    A numerically exact path integral treatment of the absorption and emission spectra of open quantum systems is presented that requires only the straightforward solution of a stochastic differential equation. The approach converges rapidly enabling the calculation of spectra of large excitonic systems across the complete range of system parameters and for arbitrary bath spectral densities. With the numerically exact absorption and emission operators, one can also immediately compute energy transfer rates using the multi-chromophoric Förster resonant energy transfer formalism. Benchmark calculations on the emission spectra of two level systems are presented demonstrating the efficacy of the stochastic approach. This is followed by calculations of the energy transfer rates between two weakly coupled dimer systems as a function of temperature and system-bath coupling strength. It is shown that the recently developed hybrid cumulant expansion (see Paper II) is the only perturbative method capable of generating uniformly reliable energy transfer rates and emission spectra across a broad range of system parameters.

  17. Exergy and Exergoenvironmental Analysis of a CCHP System Based on a Parallel Flow Double-Effect Absorption Chiller

    Directory of Open Access Journals (Sweden)

    Ali Mousafarash

    2016-01-01

    Full Text Available A combined cooling, heating, and power (CCHP system which produces electricity, heating, and cooling is modeled and analyzed. This system is comprised of a gas turbine, a heat recovery steam generator, and a double-effect absorption chiller. Exergy analysis is conducted to address the magnitude and the location of irreversibilities. In order to enhance understanding, a comprehensive parametric study is performed to see the effect of some major design parameters on the system performance. These design parameters are compressor pressure ratio, gas turbine inlet temperature, gas turbine isentropic efficiency, compressor isentropic efficiency, and temperature of absorption chiller generator inlet. The results show that exergy efficiency of the CCHP system is higher than the power generation system and the cogeneration system. In addition, the results indicate that when waste heat is utilized in the heat recovery steam generator, the greenhouse gasses are reduced when the fixed power output is generated. According to the parametric study results, an increase in compressor pressure ratio shows that the network output first increases and then decreases. Furthermore, an increase in gas turbine inlet temperature increases the system exergy efficiency, decreasing the total exergy destruction rate consequently.

  18. Automation of cell-based drug absorption assays in 96-well format using permeable support systems.

    Science.gov (United States)

    Larson, Brad; Banks, Peter; Sherman, Hilary; Rothenberg, Mark

    2012-06-01

    Cell-based drug absorption assays, such as Caco-2 and MDCK-MDR1, are an essential component of lead compound ADME/Tox testing. The permeability and transport data they provide can determine whether a compound continues in the drug discovery process. Current methods typically incorporate 24-well microplates and are performed manually. Yet the need to generate absorption data earlier in the drug discovery process, on an increasing number of compounds, is driving the use of higher density plates. A simple, more efficient process that incorporates 96-well permeable supports and proper instrumentation in an automated process provides more reproducible data compared to manual methods. Here we demonstrate the ability to perform drug permeability and transport assays using Caco-2 or MDCKII-MDR1 cells. The assay procedure was automated in a 96-well format, including cell seeding, media and buffer exchanges, compound dispense, and sample removal using simple robotic instrumentation. Cell monolayer integrity was confirmed via transepithelial electrical resistance and Lucifer yellow measurements. Proper cell function was validated by analyzing apical-to-basolateral and basolateral-to-apical movement of rhodamine 123, a known P-glycoprotein substrate. Apparent permeability and efflux data demonstrate how the automated procedure provides a less variable method than manual processing, and delivers a more accurate assessment of a compound's absorption characteristics.

  19. Fast Time-Dependent Density Functional Theory Calculations of the X-ray Absorption Spectroscopy of Large Systems.

    Science.gov (United States)

    Besley, Nicholas A

    2016-10-11

    The computational cost of calculations of K-edge X-ray absorption spectra using time-dependent density functional (TDDFT) within the Tamm-Dancoff approximation is significantly reduced through the introduction of a severe integral screening procedure that includes only integrals that involve the core s basis function of the absorbing atom(s) coupled with a reduced quality numerical quadrature for integrals associated with the exchange and correlation functionals. The memory required for the calculations is reduced through construction of the TDDFT matrix within the absorbing core orbitals excitation space and exploiting further truncation of the virtual orbital space. The resulting method, denoted fTDDFTs, leads to much faster calculations and makes the study of large systems tractable. The capability of the method is demonstrated through calculations of the X-ray absorption spectra at the carbon K-edge of chlorophyll a, C 60 and C 70 .

  20. Simulation of a combined heating, cooling and domestic hot water system based on ground source absorption heat pump

    International Nuclear Information System (INIS)

    Wu, Wei; You, Tian; Wang, Baolong; Shi, Wenxing; Li, Xianting

    2014-01-01

    Highlights: • A combined heating/cooling/DHW system based on GSAHP is proposed in cold regions. • The soil imbalance is effectively reduced and soil temperature can be kept stable. • 20% and 15% of condensation/absorption heat is recovered by GSAHP to produce DHW. • The combined system can improve the primary energy efficiency by 23.6% and 44.4%. - Abstract: The amount of energy used for heating and domestic hot water (DHW) is very high and will keep increasing. The conventional ground source electrical heat pump used in heating-dominated buildings has the problems of thermal imbalance, decrease of soil temperature, and deterioration of heating performance. Ground source absorption heat pump (GSAHP) is advantageous in both imbalance reduction and primary energy efficiency (PEE) improvement; however, the imbalance is still unacceptable in the warmer parts of cold regions. A combined heating/cooling/DHW (HCD) system based on GSAHP is proposed to overcome this problem. The GSAHPs using generator absorber heat exchange (GAX) and single-effect (SE) cycles are simulated to obtain the performance under various working conditions. Different HCD systems in Beijing and Shenyang are simulated comparatively in TRNSYS, based on which the thermal imbalance, soil temperature, heat recovery, and energy efficiency are analyzed. Results show that GSAHP–GAX–HCD is suitable for Beijing and GSAHP–SE–HCD is suitable for Shenyang. The imbalance ratio can be reduced to −14.8% in Beijing and to 6.0% in Shenyang with an annual soil temperature variation of only 0.5 °C and 0.1 °C. Furthermore, about 20% and 15% of the total condensation/absorption heat is recovered to produce DHW, and the PEE can reach 1.516 in Beijing and 1.163 in Shenyang. The combined HCD systems can achieve a PEE improvement of 23.6% and 44.4% compared with the normal heating/cooling systems

  1. Methylmercury determination using a hyphenated high performance liquid chromatography ultraviolet cold vapor multipath atomic absorption spectrometry system

    International Nuclear Information System (INIS)

    Campos, Reinaldo C.; Goncalves, Rodrigo A.; Brandao, Geisamanda P.; Azevedo, Marlo S.; Oliveira, Fabiana; Wasserman, Julio

    2009-01-01

    The present work investigates the use of a multipath cell atomic absorption mercury detector for mercury speciation analysis in a hyphenated high performance liquid chromatography assembly. The multipath absorption cell multiplies the optical path while energy losses are compensated by a very intense primary source. Zeeman-effect background correction compensates for non-specific absorption. For the separation step, the mobile phase consisted in a 0.010% m/v mercaptoethanol solution in 5% methanol (pH = 5), a C 18 column was used as stationary phase, and post column treatment was performed by UV irradiation (60 deg. C, 13 W). The eluate was then merged with 3 mol L -1 HCl, reduction was performed by a NaBH 4 solution, and the Hg vapor formed was separated at the gas-liquid separator and carried through a desiccant membrane to the detector. The detector was easily attached to the system, since an external gas flow to the gas-liquid separator was provided. A multivariate approach was used to optimize the procedure and peak area was used for measurement. Instrumental limits of detection of 0.05 μg L -1 were obtained for ionic (Hg 2+ ) and HgCH 3 + , for an injection volume of 200 μL. The multipath atomic absorption spectrometer proved to be a competitive mercury detector in hyphenated systems in relation to the most commonly used atomic fluorescence and inductively coupled plasma mass spectrometric detectors. Preliminary application studies were performed for the determination of methyl mercury in sediments.

  2. Methylmercury determination using a hyphenated high performance liquid chromatography ultraviolet cold vapor multipath atomic absorption spectrometry system

    Energy Technology Data Exchange (ETDEWEB)

    Campos, Reinaldo C. [Department of Chemistry, Pontifical Catholic University of Rio de Janeiro, Rua Marques de S Vicente 225, 22453-900 Rio de Janeiro (Brazil)], E-mail: rccampos@puc-rio.br; Goncalves, Rodrigo A.; Brandao, Geisamanda P.; Azevedo, Marlo S. [Department of Chemistry, Pontifical Catholic University of Rio de Janeiro, Rua Marques de S Vicente 225, 22453-900 Rio de Janeiro (Brazil); Oliveira, Fabiana; Wasserman, Julio [Institut of Geosciences, Fluminense Federal University, Av. Gal. Milton Tavares de Souza, s/n, 24.210-340, Niteroi, Rio de Janeiro (Brazil)

    2009-06-15

    The present work investigates the use of a multipath cell atomic absorption mercury detector for mercury speciation analysis in a hyphenated high performance liquid chromatography assembly. The multipath absorption cell multiplies the optical path while energy losses are compensated by a very intense primary source. Zeeman-effect background correction compensates for non-specific absorption. For the separation step, the mobile phase consisted in a 0.010% m/v mercaptoethanol solution in 5% methanol (pH = 5), a C{sub 18} column was used as stationary phase, and post column treatment was performed by UV irradiation (60 deg. C, 13 W). The eluate was then merged with 3 mol L{sup -1} HCl, reduction was performed by a NaBH{sub 4} solution, and the Hg vapor formed was separated at the gas-liquid separator and carried through a desiccant membrane to the detector. The detector was easily attached to the system, since an external gas flow to the gas-liquid separator was provided. A multivariate approach was used to optimize the procedure and peak area was used for measurement. Instrumental limits of detection of 0.05 {mu}g L{sup -1} were obtained for ionic (Hg{sup 2+}) and HgCH{sub 3}{sup +}, for an injection volume of 200 {mu}L. The multipath atomic absorption spectrometer proved to be a competitive mercury detector in hyphenated systems in relation to the most commonly used atomic fluorescence and inductively coupled plasma mass spectrometric detectors. Preliminary application studies were performed for the determination of methyl mercury in sedi0011men.

  3. Fate of chemicals in skin after dermal application: does the in vitro skin reservoir affect the estimate of systemic absorption?

    International Nuclear Information System (INIS)

    Yourick, Jeffrey J.; Koenig, Michael L.; Yourick, Debra L.; Bronaugh, Robert L.

    2004-01-01

    Recent international guidelines for the conduct of in vitro skin absorption studies put forward different approaches for addressing the status of chemicals remaining in the stratum corneum and epidermis/dermis at the end of a study. The present study investigated the fate of three chemicals [dihydroxyacetone (DHA), 7-(2H-naphtho[1,2-d]triazol-2-yl)-3-phenylcoumarin (7NTPC), and disperse blue 1 (DB1)] in an in vitro absorption study. In these studies, human and fuzzy rat skin penetration and absorption were determined over 24 or 72 h in flow-through diffusion cells. Skin penetration of these chemicals resulted in relatively low receptor fluid levels but high skin levels. For DHA, penetration studies found approximately 22% of the applied dose remaining in the skin (in both the stratum corneum and viable tissue) as a reservoir after 24 h. Little of the DHA that penetrates into skin is actually available to become systemically absorbed. 7NTPC remaining in the skin after 24 h was approximately 14.7% of the applied dose absorbed. Confocal laser cytometry studies with 7NTPC showed that it is present across skin in mainly the epidermis and dermis with intense fluorescence around hair. For DB1, penetration studies found approximately 10% (ethanol vehicle) and 3% (formulation vehicle) of the applied dose localized in mainly the stratum corneum after 24 h. An extended absorption study (72 h) revealed that little additional DB1 was absorbed into the receptor fluid. Skin levels should not be considered as absorbed material for DHA or DB1, while 7NTPC requires further investigation. These studies illustrate the importance of determining the fate of chemicals remaining in skin, which could significantly affect the estimates of systemically available material to be used in exposure estimates. We recommend that a more conclusive means to determine the fate of skin levels is to perform an extended study as conducted for DB1

  4. Application of the exergetic cost theory to the LiBr/H2O vapour absorption system

    International Nuclear Information System (INIS)

    Misra, R.D.; Sahoo, P.K.; Gupta, A.

    2002-01-01

    Optimization of thermal systems is generally based on thermodynamic analysis. However, the systems so optimized often are not viable due to economic constraints. The Theory of Exergetic Cost, a thermoeconomic optimization technique, combines the thermodynamic analysis with that of economic constraints to obtain an optimum configuration of a thermal system. In this paper, this technique is applied to optimize a LiBr/H 2 O vapour absorption refrigeration system run by pressurized hot water for air-conditioning applications. The mathematical and numerical techniques-based optimization of thermal systems is not always possible due to plant complexities. Hence, a simplified cost minimization methodology, based on 'Theory of Exergetic Cost', is applied to evaluate the economic costs of all the internal flows and products of the system under consideration. As shown in this paper, once these costs are determined, an approximately optimum design configuration can be obtained

  5. High-dispersion observations of H-alpha in the suspected brown dwarf, white dwarf binary system G29-38

    International Nuclear Information System (INIS)

    Liebert, J.; Saffer, R.A.; Pilachowski, C.A.

    1989-01-01

    High-dispersion spectroscopy of the H-alpha absorption line of the cool DA white dwarf G29-38 is reported. This is the star for which a recently detected IR excess has been suggested to be due to a possible brown dwarf companion. Three echelle spectra show no evidence for radial-velocity variations larger than about 1.1 + or - 8.7 km/s and are used to derive a weighted heliocentric radial velocity of 33.7 + or - 4.3 kms/s for the white dwarf. The observations of a sharp absorption-line core restricts the possible rotation of the white dwarf to 40 km/s or less and ensures that any surface magnetic field has a strength of 100,000 G or less. These results make it unlikely that the DA white dwarf has previously been in a cataclysmic variable accretion phase. 18 references

  6. Evaluation of a flue gas driven open absorption system for heat and water recovery from fossil fuel boilers

    International Nuclear Information System (INIS)

    Wang, Zhenying; Zhang, Xiaoyue; Li, Zhen

    2016-01-01

    Highlights: • Flue gas driven open absorption system that efficiently recovers total heat. • Efficient heat and water recovery for various kinds of fossil fuel boilers. • Heat and water recovery efficiencies increase with moisture content of flue gas. • Temperature requirements for district heat supply and domestic hot water were met. • Experimental system surpasses conventional condensing system in total heat recovery. - Abstract: This paper presents an open absorption system for total heat recovery from fossil fuel boilers using the high temperature flue gas as the regeneration heat source. In this system, liquid desiccant serves as the recycling medium, which absorbs waste heat and moisture contained in the low temperature flue gas in the packed tower and then regenerates in the regenerator by the high temperature flue gas. Water vapor generated in the regenerator gets condensed after releasing heat to the heating water system and the condensing water also gets recycled. The return water collects heat from the solution water heat exchanger, the flue gas water heat exchanger and the condenser respectively and is then used for district heating. Driven by the vapor pressure difference between high humidity flue gas and the liquid desiccant, the heat recovery efficiency of the system is not limited by the dew point of the flue gas, enabling a warmer water to be heated up than the conventional condensing boiler. The performance of this system was analyzed theoretically and experimentally and the results showed that the system operated well for both district heat supply and domestic hot water supply. The system efficiency increased with the moisture content of flue gas and the total heat recovery was about 8.5%, 17.2%, 21.2%, and 9.2% higher than the conventional condensing system in the case of coal fired boiler, fuel oil boiler, natural gas boiler, and coke oven gas boiler, respectively.

  7. Calcium absorption

    International Nuclear Information System (INIS)

    Carlmark, B.; Reizenstein, P.; Dudley, R.A.

    1976-01-01

    The methods most commonly used to measure the absorption and retention of orally administered calcium are reviewed. Nearly all make use of calcium radioisotopes. The magnitude of calcium absorption and retention depends upon the chemical form and amount of calcium administered, and the clinical and nutritional status of the subject; these influences are briefly surveyed. (author)

  8. Optical absorption studies on biodegradable PVA/PVP blend polymer electrolyte system

    Science.gov (United States)

    Basha, S. K. Shahenoor; Reddy, K. Veera Bhadra; Rao, M. C.

    2018-05-01

    Biodegradable blend polymer electrolytes of PVA/PVP with different wt% ratios of MgCl2.6H2O have been prepared using solution cast technique. Optical absorption studies were carried-out on to the prepared films at room temperature using JASCO V-670 Spectrophotometer in the wavelength region 200-600 nm. Due to the clusters between the vibrations of molecules a broad peak is obtained due to п-п* transition in the wavelength region 310-340 nm.

  9. The mechanism and properties of bio-photon emission and absorption in protein molecules in living systems

    Science.gov (United States)

    Pang, Xiao-feng

    2012-05-01

    The mechanism and properties of bio-photon emission and absorption in bio-tissues were studied using Pang's theory of bio-energy transport, in which the energy spectra of protein molecules are obtained from the discrete dynamic equation. From the energy spectra, it was determined that the protein molecules could both radiate and absorb bio-photons with wavelengths of energy level transitions of the excitons. These results were consistent with the experimental data; this consisted of infrared absorption data from collagen, bovine serum albumin, the protein-like molecule acetanilide, plasma, and a person's finger, and the laser-Raman spectra of acidity I-type collagen in the lungs of a mouse, and metabolically active Escherichia coli. We further elucidated the mechanism responsible for the non-thermal biological effects produced by the infrared light absorbed by the bio-tissues, using the above results. No temperature rise was observed; instead, the absorbed infrared light promoted the vibrations of amides as well the transport of the bio-energy from one place to other in the protein molecules, which changed their conformations. These experimental results, therefore, not only confirmed the validity of the mechanism of bio-photon emission, and the newly developed theory of bio-energy transport mentioned above, but also explained the mechanism and properties of the non-thermal biological effects produced by the absorption of infrared light by the living systems.

  10. Design and analysis of a waste gasification energy system with solid oxide fuel cells and absorption chillers

    DEFF Research Database (Denmark)

    Rokni, Masoud

    2018-01-01

    Energy saving is an open point in most European countries where energy policies are oriented to reduce the use of fossil fuels, greenhouses emissions and energy independence, and to increase the use of renewable energies. In the last several years, new technologies have been developed and some...... of them received subsidies to increase installation and reduce cost. This article presents a new sustainable trigeneration system (power, heat and cool) based on a solid oxide fuel cell (SOFC) system integrated with an absorption chiller for special applications such as hotels, resorts, hospitals, etc....... with a focus on plant design and performance. The proposal system is based on the idea of gasifying the municipal waste, producing syngas serving as fuel for the trigeneration system. Such advanced system when improved is thus self-sustainable without dependency on net grid, district heating and district...

  11. Absorption studies

    International Nuclear Information System (INIS)

    Ganatra, R.D.

    1992-01-01

    Absorption studies were once quite popular but hardly anyone does them these days. It is easier to estimate the blood level of the nutrient directly by radioimmunoassay (RIA). However, the information obtained by estimating the blood levels of the nutrients is not the same that can be obtained from the absorption studies. Absorption studies are primarily done to find out whether some of the essential nutrients are absorbed from the gut or not and if they are absorbed, to determine how much is being absorbed. In the advanced countries, these tests were mostly done to detect pernicious anaemia where vitamin B 12 is not absorbed because of the lack of the intrinsic factor in the stomach. In the tropical countries, ''malabsorption syndrome'' is quire common. In this condition, several nutrients like fat, folic acid and vitamin B 12 are not absorbed. It is possible to study absorption of these nutrients by radioisotopic absorption studies

  12. Infrared reflection absorption spectroscopy study of radiation-heterogeneous processes in the system of aluminum-hexane

    International Nuclear Information System (INIS)

    Gadzhieva, N.N.; Rimikhanova, A.N.; Garibov, A.A.

    2004-01-01

    Full text: Infrared reflection absorption spectroscopy (IRRAS) was applied to study the regularities of radiation conversion of hexane on the surface of aluminum. The research object was the thin polished aluminum plate by mark of AD-00 with reflection coefficient R=0.8†0.85 in infrared range λ=2.2†15 μ . As adsorbate unsaturated vapors of spectroscopy clear hexane were used. The absorption of hexane (C 2 H 14 ) was being studied manometric at pressures P=(0.1†1.0)·10 2 Pa , what corresponded to monolayer value of 1-10. The samples were irradiated with γ-quanta of 60 Co with D=1.03 Gy·s -1 doze rate. Infrared reflection spectrum when linear-polarized radiation fall on the sample under angle ψ=10 o was measured by spectrophotometer 'Specord 71 JR' in diapason of 4000-650cm -1 at the temperature by mean of special reflecting arrangements. Formation of molecular hydrogen (H 2 ) and other gaseous products of decomposition were controlled by chromotographical and infrared spectroscopical methods. The analysis of hexane infrared absorption spectra after radiation-stimulated adsorption on the surface of aluminum, points out the formation of H-bonded hydrocarbon complex ( ν∼2680cm -1 ) with much loosening of C-H bond (the molecular form of absorption) and the possibility of proceeding dissociative absorption with formation of metal-alkyls (ν∼2880, 2920, 2970 cm -1 ). Probability of the last mentioned process, which proceeds in the most defective centers, increases with increasing of γ-radiation doze. It was established that the radiation processes in hetero system Al-ads.C 6 H 14 accelerate the radiolysis of hexane. At all these the radiation decomposition of hexane in hetero system Al-ads.C 6 H 14 is accompanied by formation the surface hydrides (ν∼1700-2000 cm -1 ), acetylene (ν∼3200-3300 cm -1 ), ethylene (ν∼980 cm -1 ), and also gaseous products of molecular hydrogen decomposition (H 2 ) and hydrocarbons C 1 -C 5 (bands with maxima 770, 790

  13. Atomic absorption determination of ultratrace tellurium in rocks utilizing high sensitivity sampling systems

    International Nuclear Information System (INIS)

    Beaty, R.D.

    1973-01-01

    The sampling boat and the graphite furnace were shown to possess the required sensitivity to detect tellurium at ultratrace levels, in a variety of sample types, by atomic absorption. In the sampling boat approach, tellurium in sample solutions is chemically separated and concentrated by extraction into methyl isobutyl ketone before measurement. For samples exhibiting extraction interferences or excessively high background absorption, a preliminary separation of tellurium by coprecipitation with selenium is described. Using this technique, tellurium can be quantitatively detected down to 5 nanograms and linear response is observed to 100 nanograms. Relative standard deviations of better than 7 percent are achieved for 50 nanograms of tellurium. For samples that have a tellurium content below the detection limits of the sampling boat, the graphite furnace is used for atomization. By this method, as little as 0.07 nanograms of tellurium can be detected, and a precision of 1 percent relative standard deviation is achievable at the 5 nanogram level. A routinely applicable procedure was developed for determining tellurium in rocks, using the graphite furnace, after a hydrofluoric acid decomposition of the sample. Using this procedure, tellurium data were obtained on 20 different rocks, and the significance of this new information is discussed. (Diss. Abstr. Int., B)

  14. Plasmon-enhanced absorption in a metal nanoparticles and photosynthetic molecules hybrid system

    Science.gov (United States)

    Fan, Zhiyuan; Govorov, Alexander

    2010-03-01

    Photosystem I from cyanobacteria is one of nature's most efficient light harvesting complexes, converting light energy into electronic energy with a quantum yield of 100% and an energy yield about 58%. It is very attractive to the nanotechnology community because of its nanoscale dimensions and excellent optoelectronic properties. This protein has the potential to be utilized in devices such as solar cells, electric switches, photo-detectors, etc. However, there is one limiting factor for potential applications of a single monolayer of these photosynthetic proteins. One monolayer absorbs less than 1% of sunlight's energy, despite their excellent optoelectronic properties. Recently, experiments [1] have been conducted to enhance light absorption with the assistance of metal nanoparticles as artificial antenna for the photosystem I. Here, we present a theoretical description of the strong plasmon-assisted interactions between the metal nanoparticles and the optical dipoles of the reaction centers observed in the experiments. The resonance and off-resonance plasmon effects enhance the electromagnetic fields around the photosystem-I molecules and, in this way, lead to enhanced absorption. [4pt] [1] I. Carmeli, I. Lieberman, L. Kraversky, Zhiyuan Fan, A. O. Govorov, G. Markovich, and S. Richter, submitted.

  15. Critical coupling and coherent perfect absorption for ranges of energies due to a complex gain and loss symmetric system

    International Nuclear Information System (INIS)

    Hasan, Mohammad; Ghatak, Ananya; Mandal, Bhabani Prasad

    2014-01-01

    We consider a non-Hermitian medium with a gain and loss symmetric, exponentially damped potential distribution to demonstrate different scattering features analytically. The condition for critical coupling (CC) for unidirectional wave and coherent perfect absorption (CPA) for bidirectional waves are obtained analytically for this system. The energy points at which total absorption occurs are shown to be the spectral singular points for the time reversed system. The possible energies at which CC occurs for left and right incidence are different. We further obtain periodic intervals with increasing periodicity of energy for CC and CPA to occur in this system. -- Highlights: •Energy ranges for CC and CPA are obtained explicitly for complex WS potential. •Analytical conditions for CC and CPA for PT symmetric WS potential are obtained. •Conditions for left and right CC are shown to be different. •Conditions for CC and CPA are shown to be that of SS for the time reversed system. •Our model shows the great flexibility of frequencies for CC and CPA

  16. Cooling performance and energy saving of a compression-absorption refrigeration system driven by a gas engine

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Z.G.; Guo, K.H. [Sun Yat-Sen University, Guangzhou (China). Engineering School

    2006-07-01

    The prototype of combined vapour compression-absorption refrigeration system was set up, where a gas engine drove directly an open screw compressor in a vapour compression refrigeration chiller and waste heat from the gas engine was used to operate absorption refrigeration cycle. The experimental procedure and results showed that the combined refrigeration system was feasible. The cooling capacity of the prototype reached about 589 kW at the Chinese rated conditions of air conditioning (the inlet and outlet temperatures of chilled water are 12 and 7{sup o}C, the inlet and outlet temperatures of cooling water are 30 and 35{sup o}C, respectively). Primary energy rate (PER) and comparative primary energy saving were used to evaluate energy utilization efficiency of the combined refrigeration system. The calculated results showed that the PER of the prototype was about 1.81 and the prototype saved more than 25% of primary energy compared to a conventional electrically driven vapour compression refrigeration unit. Error analysis showed that the total error of the combined cooling system measurement was about 4.2% in this work. (author)

  17. Use of process steam in vapor absorption refrigeration system for cooling and heating applications: An exergy analysis

    Directory of Open Access Journals (Sweden)

    S. Anand

    2016-12-01

    Full Text Available The exponential increase in cost of conventional fuels shifts the interest toward the use of alternative as well waste energy sources for the operation of refrigeration and air-conditioning units. The present study therefore analyzes the performance of a process steam-operated vapor absorption system for cooling and heating applications using ammonia and water as working fluids based on first and second laws of thermodynamics. A mathematical model has been developed based on exergy analysis to investigate the performance of the system. The different performance parameters such as coefficient of performance (COP and exergetic efficiency of absorption system for cooling and heating applications are also calculated under different operating conditions. The results obtained show that cooling and heating COP along with second law efficiency (exergy efficiency increases with the heat source temperature at constant evaporator, condenser, and absorber temperature. Also, COP as well as exergy efficiency increases with an increase in the evaporator temperature at constant generator, condenser, and absorber temperature. The effect of ambient temperature on the exergetic efficiency for cooling and heating applications is also studied. The results obtained from the simulation studies can be used to optimize different components of the system so that the performance can be improved significantly.

  18. Effects of x-ray irradiation on the induction of. cap alpha. -amylase synthesis by gibberelic acid in the aleurone system of barley

    Energy Technology Data Exchange (ETDEWEB)

    Zellner, H

    1974-01-01

    The influence of ionizing radiation on a system without DNA replication and cell division was investigated with the aid of GA/sub 3/-induced ..cap alpha..-amylase synthesis in aleurone cells of barley. The reaction of the system was determined by dose effect curves (after irradiation of one half of the endosperms in rest) for the synthesis and secretion of ..cap alpha..-amylase, protein, and reducing sugars. The system proves to be highly radiation-resistant. The course of the synthesis of ..cap alpha..-amylase after X-ray irradiation with varying doses during enzyme synthesis suggests that transcription occurs in the middle of the lag-phase and is the most sensitive stage in enzyme synthesis, while translation alone is less sensitive to radiation.

  19. A comprehensive, multi-objective optimization of solar-powered absorption chiller systems for air-conditioning applications

    International Nuclear Information System (INIS)

    Shirazi, Ali; Taylor, Robert A.; Morrison, Graham L.; White, Stephen D.

    2017-01-01

    Highlights: • Multi-objective optimization of solar single/multi-effect absorption chillers was conducted. • Primary energy consumption and total annual cost were considered as the objectives. • Optimized designs of the alternative configurations were compared. • A detailed sensitivity analysis of the Pareto optimal solutions was investigated. - Abstract: Solar heating and cooling (SHC) systems are currently under rapid development and deployment due to their potential to reduce the use of fossil fuel resources and to alleviate greenhouse gas emissions in the building sector – a sector which is responsible for ∼40% of the world energy use. Absorption chiller technology (traditionally powered by natural gas in large buildings), can easily be retrofitted to run on solar energy. However, numerous non-intuitive design choices must be analyzed to achieve the best techno-economic performance of these systems. To date, there has been little research into the optimal configurations among the long list of potential solar-driven absorption chiller systems. To address this lack of knowledge, this paper presents a systematic simulation-based, multi-objective optimization of three common, commercially available lithium bromide-water absorption chillers – single-effect, double-effect and triple-effect – powered by evacuated tube collectors (ETCs), evacuated flat plate collectors (EFPCs), and concentrating parabolic trough collectors (PTCs), respectively. To the best of authors’ knowledge, this is the first study of its kind that compares the optimized designs of the most promising configurations of solar-assisted absorption chillers against a common set of energy, economic, and environmental metrics from a holistic perspective. A simulation model of these three configurations is developed using TRNSYS 17. A combined energy, economic, and environmental analysis of the modeled systems is conducted to calculate the primary energy use as well as the levelized total

  20. Fixed-wavelength H2O absorption spectroscopy system enhanced by an on-board external-cavity diode laser

    International Nuclear Information System (INIS)

    Brittelle, Mack S; Simms, Jean M; Sanders, Scott T; Gord, James R; Roy, Sukesh

    2016-01-01

    We describe a system designed to perform fixed-wavelength absorption spectroscopy of H 2 O vapor in practical combustion devices. The system includes seven wavelength-stabilized distributed feedback (WSDFB) lasers, each with a spectral accuracy of  ±1 MHz. An on-board external cavity diode laser (ECDL) that tunes 1320–1365 nm extends the capabilities of the system. Five system operation modes are described. In one mode, a sweep of the ECDL is used to monitor each WSDFB laser wavelength with an accuracy of  ±30 MHz. Demonstrations of fixed-wavelength thermometry at 10 kHz bandwidth in near-room-temperature gases are presented; one test reveals a temperature measurement error of ∼0.43%. (paper)

  1. Monte Carlo alpha calculation

    Energy Technology Data Exchange (ETDEWEB)

    Brockway, D.; Soran, P.; Whalen, P.

    1985-01-01

    A Monte Carlo algorithm to efficiently calculate static alpha eigenvalues, N = ne/sup ..cap alpha..t/, for supercritical systems has been developed and tested. A direct Monte Carlo approach to calculating a static alpha is to simply follow the buildup in time of neutrons in a supercritical system and evaluate the logarithmic derivative of the neutron population with respect to time. This procedure is expensive, and the solution is very noisy and almost useless for a system near critical. The modified approach is to convert the time-dependent problem to a static ..cap alpha../sup -/eigenvalue problem and regress ..cap alpha.. on solutions of a/sup -/ k/sup -/eigenvalue problem. In practice, this procedure is much more efficient than the direct calculation, and produces much more accurate results. Because the Monte Carlo codes are intrinsically three-dimensional and use elaborate continuous-energy cross sections, this technique is now used as a standard for evaluating other calculational techniques in odd geometries or with group cross sections.

  2. Performance analysis of solar air cooled double effect LiBr/H2O absorption cooling system in subtropical city

    International Nuclear Information System (INIS)

    Li, Zeyu; Ye, Xiangyang; Liu, Jinping

    2014-01-01

    Highlights: • The meteorological data during the working period of air conditioning was measured. • The suitable working range of collector temperature of system was gotten. • The characteristic of hourly and monthly total efficiency of system were obtained. • The yearly performance of system was calculated. - Abstract: Due to the absence of cooling tower and independent on water, the air cooled solar double effect LiBr/H 2 O absorption cooling system is more convenient to be used in commercial building and household use. The performance with collector temperature is an important field for such system. The paper mainly deals with the performance with collector temperature for the solar air cooled double effect LiBr/H 2 O absorption cooling system in subtropical city. The parameters of system are: aperture area of collector array is 27 m 2 , tilted angle of collector with respect to the horizontal plane is 20 toward to south evaporator temperature is 5 °C and the cooling capacity is 20 kW. The simulation is based on the meteorological data of monthly typical day which was summarized from a year round measured data. A corresponding parametric model was developed. The hourly and average performance with the collector temperature for monthly typical day was obtained and discussed. It was found that the suitable working range of inlet temperature of collector is 110–130 °C to improve performance and lower the risk of crystallization. The difference of hourly total efficiency in 9:00–16:00 is less, and the monthly total efficiency from May to October is approximate. The yearly performance of system including total efficiency, cooling capacity per area of collector and solar fraction was given. Furthermore, the effect of effectiveness of heat exchanger and pressure drop on total efficiency and solar fraction was studied and compared. The paper can serve as a preliminary investigation of solar air cooled double effect LiBr/H 2 O absorption cooling system in

  3. Design of a mixer for the thrust-vectoring system on the high-alpha research vehicle

    Science.gov (United States)

    Pahle, Joseph W.; Bundick, W. Thomas; Yeager, Jessie C.; Beissner, Fred L., Jr.

    1996-01-01

    One of the advanced control concepts being investigated on the High-Alpha Research Vehicle (HARV) is multi-axis thrust vectoring using an experimental thrust-vectoring (TV) system consisting of three hydraulically actuated vanes per engine. A mixer is used to translate the pitch-, roll-, and yaw-TV commands into the appropriate TV-vane commands for distribution to the vane actuators. A computer-aided optimization process was developed to perform the inversion of the thrust-vectoring effectiveness data for use by the mixer in performing this command translation. Using this process a new mixer was designed for the HARV and evaluated in simulation and flight. An important element of the Mixer is the priority logic, which determines priority among the pitch-, roll-, and yaw-TV commands.

  4. Folate absorption

    International Nuclear Information System (INIS)

    Baker, S.J.

    1976-01-01

    Folate is the generic term given to numerous compounds of pteroic acid with glutamic acid. Knowledge of absorption is limited because of the complexities introduced by the variety of compounds and because of the inadequacy of investigational methods. Two assay methods are in use, namely microbiological and radioactive. Techniques used to study absorption include measurement of urinary excretion, serum concentration, faecal excretion, intestinal perfusion, and haematological response. It is probably necessary to test absorption of both pteroylmonoglutamic acid and one or more polyglutamates, and such tests would be facilitated by availability of synthesized compounds labelled with radioactive tracers at specifically selected sites. (author)

  5. Immunoreactive serum opsonic alpha 2 sb glycoprotein as a noninvasive index of RES systemic defense after trauma.

    Science.gov (United States)

    Kaplan, J E; Saba, T M

    1979-01-01

    Reticuloendothelial system (RES) depression has been correlated with diminished resistance to trauma, shock, and sepsis in man and animals. Previous studies have related the depression of RES hepatic Kupffer cell phagocytic function after trauma to diminished bioassayable opsonic activity. The present study determined if the loss of biological activity and RES alteration correlated with immunoreactive serum opsonic alpha 2 SB glycoprotein levels after trauma. Serum opsonic activity was measured by liver slice bioassay, and immunoreactive opsonic protein was measured by rocket electroimmunoassay. RE function was determined by colloid clearance over a 24-hour post-trauma period. Anesthetized rats (250-300 gm) subjected to sublethal or severe (greater than LD50) whole-body NCD trauma were the shock models investigated. Immunoreactive levels in 63 rats prior to injury were 518 +/- 24 microgram/ml. Neither biological nor immunoreactive levels were altered over 24 hours in anesthetized sham-traumatized controls. Temporal alteration in the initial decrease and recovery pattern of biologically active and immunoreactive opsonic protein levels significantly correlated following both sublethal and severe injury. Moreover, the patterns of immunoreactive levels of the opsonic protein correlated with the functional phagocytic activity of the RES as determined by vascular clearance of a test dose of blood-borne radiolabeled particulates. This glycoprotein falls after trauma, and the magnitude and duration of the decline increases with severity of injury. Immunoreactive opsonic alpha 2 SB glycoprotein appears to be an accurate measurement of circulating opsonic activity and RE Kupffer cell function after trauma, especially with respect to clearance. Thus, immunoreactive opsonic protein warrants clinical consideration as a noninvasive measure of reticuloendothelial systemic defense in patients after trauma and burn.

  6. An antiaging skin care system containing alpha hydroxy acids and vitamins improves the biomechanical parameters of facial skin

    Directory of Open Access Journals (Sweden)

    Tran D

    2014-12-01

    Full Text Available Diana Tran, Joshua P Townley, Tanya M Barnes, Kerryn A Greive Ego Pharmaceuticals, Braeside, Victoria, Australia Background: The demand for antiaging products has dramatically increased in recent years, driven by an aging population seeking to maintain the appearance of youth. This study investigates the effects of an antiaging skin care system containing alpha hydroxy acids (AHAs in conjunction with vitamins B3, C, and E on the biomechanical parameters of facial skin. Methods: Fifty two volunteers followed an antiaging skin care regimen comprising of cleanser, eye cream, day moisturizer, and night moisturizer for 21 days. Wrinkle depth (Ry and skin roughness (Ra were measured by skin surface profilometry of the crow's feet area, and skin elasticity parameters R2 (gross elasticity, R5 (net elasticity, R6 (viscoelastic portion, and R7 (recovery after deformation were determined for facial skin by cutometer, preapplication and after 7, 14, and 21 days. Volunteers also completed a self-assessment questionnaire. Results: Compared to baseline, Ry and Ra significantly improved by 32.5% (P<0.0001 and 42.9% (P<0.0001, respectively, after 21 days of antiaging skin care treatment. These results were observed by the volunteers with 9 out of 10 discerning an improvement in skin texture and smoothness. Compared to baseline, R2 and R5 significantly increased by 15.2% (P<0.0001 and 12.5% (P=0.0449, respectively, while R6 significantly decreased by 17.7% (P<0.0001 after 21 days. R7 increased by 9.7% after 21 days compared to baseline but this was not significant over this time period. Conclusion: An antiaging skin care system containing AHAs and vitamins significantly improves the biomechanical parameters of the skin including wrinkles and skin texture, as well as elasticity without significant adverse effects. Keywords: alpha hydroxy acids, antiaging, nicotinamide, vitamin C, vitamin E, profilometry, cutometer

  7. A system to measure suprathermal electron distribution functions in toroidal plasmas by electron cyclotron wave absorption

    International Nuclear Information System (INIS)

    Boyd, D.A.; Skiff, F.; Gulick, S.

    1997-01-01

    A two-chord, four-beam suprathermal electron diagnostic has been installed on TdeV (B>1.5 T, R=0.86 m, a=0.25 m). Resonant absorption of extraordinary mode electron cyclotron waves is measured to deduce the chordal averaged suprathermal electron distribution function amplitude at the resonant momentum. Simultaneously counterpropagating beams permit good refractive loss cancellation. A nonlinear frequency sweep leads to a concentration of appropriately propagating power in a narrow range of time of flight, thus increasing the signal-to-noise ratio and facilitating the rejection of spurious reflections. Numerous measurements of electron distribution functions have been obtained during lower-hybrid current-drive experiments. copyright 1997 American Institute of Physics

  8. X-ray absorption spectroscopy of diluted system by undulator photon source and multi-element solid-state detector

    CERN Document Server

    Tanida, H

    2001-01-01

    In order to measure the extended X-ray absorption fine structure (EXAFS) spectrum of an ultra-diluted system, an optics and detector control system for a synchrotron radiation beamline is developed. The undulator gap width is continuously tuned to obtain the maximum X-ray photon flux during the energy scan for the EXAFS measurement. A piezoelectric translator optimizes the parallelism of the double crystal in a monochromator at each measurement point to compensate for mechanical errors of the monochromator, resulting in a smooth and intense X-ray photon flux during the measurement. For a detection of a weak fluorescence signal from diluted samples, a 19-element solid-state detector and digital signal processor are used. A K-edge EXAFS spectrum of iron in a myoglobin aqueous solution with a concentration of 5.58 parts per million was obtained by this system.

  9. On design of absorption, regeneration and recovery system of low concentration hydrogen and tritium in He with titanium sponge

    International Nuclear Information System (INIS)

    Fukuhara, Masashi

    1978-01-01

    Design of a titanium sponge system to remove hydrogen from the helium coolant of high temperature gas-cooled reactors or fusion reactors is discussed in this paper. The data for the present purpose have been accumulated. The equilibrium relation of Ti-H 2 system was given by McQuillan. The present author of this paper obtained an absorption equilibrium diagram, and measurements were made for lower partial pressure than that of McQuillan's data. A breakthrough curve and an adsorption-desorption breakthrough curve of H 2 -Ti sponge system, and the regeneration characteristics of the Ti sponge were measured. As the results of experiments, it is said that tritium and hydrogen can be removed with a Ti sponge system. Examples of the design of a practical system are presented. A disposable system was designed for OGL-1 under the principle that the used Ti sponge is a solid radioactive waste. A regenerative system was designed as a system, in which solid radioactive wastes are not produced. An example of a recovery system is also presented. Discussion on the reason why the Ti-sponge has not been used is presented. (Kato, T.)

  10. Design of absorption, regeneration and recovery system of low concentration hydrogen and tritium in He with titanium sponge

    Energy Technology Data Exchange (ETDEWEB)

    Fukuhara, M [Kawasaki Heavy Industries Ltd., Kobe (Japan)

    1978-10-01

    Design of a titanium sponge system to remove hydrogen from the helium coolant of high temperature gas-cooled reactors or fusion reactors is discussed in this paper. The data for the present purpose have been accumulated. The equilibrium relation of Ti-H/sub 2/ system was given by McQuillan. The present author of this paper obtained an absorption equilibrium diagram, and measurements were made for lower partial pressure than that of McQuillan's data. A breakthrough curve and an adsorption-desorption breakthrough curve of H/sub 2/-Ti sponge system, and the regeneration characteristics of the Ti sponge were measured. As the results of experiments, it is said that tritium and hydrogen can be removed with a Ti sponge system. Examples of the design of a practical system are presented. A disposable system was designed for OGL-1 under the principle that the used Ti sponge is a solid radioactive waste. A regenerative system was designed as a system, in which solid radioactive wastes are not produced. An example of a recovery system is also presented. Discussion on the reason why the Ti-sponge has not been used is presented.

  11. Treatment of alpha bearing wastes

    International Nuclear Information System (INIS)

    1988-01-01

    This report deals with the current state of the art of alpha waste treatment, which is an integral part of the overall nuclear waste management system. The International Atomic Energy Agency (IAEA) defines alpha bearing waste as 'waste containing one or more alpha emitting radionuclides, usually actinides, in quantities above acceptable limits'. The limits are established by national regulatory bodies. The limits above which wastes are considered as alpha contaminated refer to the concentrations of alpha emitters that need special consideration for occupational exposures and/or potential safety, health, or environmental impact during one or more steps from generation through disposal. Owing to the widespread use of waste segregation by source - that is, based upon the 'suspect origin' of the material - significant volumes of waste are being handled as alpha contaminated which, in fact, do not require such consideration by reason of risk or environmental concern. The quantification of de minimis concepts by national regulatory bodies could largely contribute to the safe reduction of waste volumes and associated costs. Other factors which could significantly contribute to the reduction of alpha waste arisings are an increased application of assaying and sorting, instrumentation and the use of feedback mechanisms to control or modify the processes which generate these wastes. Alpha bearing wastes are generated during fabrication and reprocessing of nuclear fuels, decommissioning of alpha contaminated facilities, and other activities. Most alpha wastes are contact handled, but a small portion may require shielding or remote handling because of high levels of neutron (n), beta (β), or gamma (γ) emissions associated with the waste material. This report describes the sources and characteristics of alpha wastes and strategies for alpha waste management. General descriptions of treatment processes for solid and liquid alpha wastes are included. 71 refs, 14 figs, 9 tabs

  12. SIMULATION OF SOLAR LITHIUM BROMIDE–WATER ABSORPTION COOLING SYSTEM WITH DOUBLE GLAZED FLAT PLATE COLLECTOR FOR ADRAR

    Directory of Open Access Journals (Sweden)

    ML CHOUGUI

    2014-12-01

    Full Text Available Adrar is a city in the Sahara desert, in southern Algeria known for its hot and dry climate, where a huge amount of energy is used for air conditioning. The aim of this research is to simulate a single effect lithium bromide–water absorption chiller coupled to a double-glazed flat plate collector to supply the cooling loads for a house of 200m2 in Adrar. The thermal energy is stored in an insulated thermal storage tank. The system was designed to cover a cooling load of 10.39KW for design day of July. Thermodynamic model was established to simulate the absorption cycle. The results have shown that the collector mass flow rate has a negligible effect on the minimum required collector area, but it has a significant effect on the optimum capacity of the storage tank. The minimum required collector area was about 65.3 m2, which could supply the cooling loads for the sunshine hours of the design day for July. The operation of the system has also been considered after sunset by saving solar energy.

  13. Measurement system to detect minute quantity of plutonium and other alpha emitter

    International Nuclear Information System (INIS)

    Simon, G.G.; Eyrich, W.

    1990-01-01

    Presently, the most highly developed method in use is the time correlation analysis method (TCA). With special equipped electronics and computer system designed for the TCA method, the time correlation of the registered events is used to determine the contribution of different multiplets. Thus, the efficiency of the measurement system and the isotopic composition of the probe can be determined and thereby the Plutonium content is calculated. In the case of minute contents of Plutonium, the TCA method is insufficient to calculate the efficiency of the measurement system because of the large statistical error relative to the fluctuation of the background counting rate. This paper reports that in addition to the TCA method, the local correlation analysis (LCA) was developed at the Nuclear Research Center in Karlsruhe (KfK) to yield more information. The efficiency of the measurement system can be calculated taking into account the lifetime of the neutrons in the measurement system and the probe position

  14. Effects of gastric pH on oral drug absorption: In vitro assessment using a dissolution/permeation system reflecting the gastric dissolution process.

    Science.gov (United States)

    Kataoka, Makoto; Fukahori, Miho; Ikemura, Atsumi; Kubota, Ayaka; Higashino, Haruki; Sakuma, Shinji; Yamashita, Shinji

    2016-04-01

    The aim of the present study was to evaluate the effects of gastric pH on the oral absorption of poorly water-soluble drugs using an in vitro system. A dissolution/permeation system (D/P system) equipped with a Caco-2 cell monolayer was used as the in vitro system to evaluate oral drug absorption, while a small vessel filled with simulated gastric fluid (SGF) was used to reflect the gastric dissolution phase. After applying drugs in their solid forms to SGF, SGF solution containing a 1/100 clinical dose of each drug was mixed with the apical solution of the D/P system, which was changed to fasted state-simulated intestinal fluid. Dissolved and permeated amounts on applied amount of drugs were then monitored for 2h. Similar experiments were performed using the same drugs, but without the gastric phase. Oral absorption with or without the gastric phase was predicted in humans based on the amount of the drug that permeated in the D/P system, assuming that the system without the gastric phase reflected human absorption with an elevated gastric pH. The dissolved amounts of basic drugs with poor water solubility, namely albendazole, dipyridamole, and ketoconazole, in the apical solution and their permeation across a Caco-2 cell monolayer were significantly enhanced when the gastric dissolution process was reflected due to the physicochemical properties of basic drugs. These amounts resulted in the prediction of higher oral absorption with normal gastric pH than with high gastric pH. On the other hand, when diclofenac sodium, the salt form of an acidic drug, was applied to the D/P system with the gastric phase, its dissolved and permeated amounts were significantly lower than those without the gastric phase. However, the oral absorption of diclofenac was predicted to be complete (96-98%) irrespective of gastric pH because the permeated amounts of diclofenac under both conditions were sufficiently high to achieve complete absorption. These estimations of the effects of

  15. Assessment of the performance of a compact concentric spectrometer system for Atmospheric Differential Optical Absorption Spectroscopy

    Science.gov (United States)

    Whyte, C.; Leigh, R. J.; Lobb, D.; Williams, T.; Remedios, J. J.; Cutter, M.; Monks, P. S.

    2009-12-01

    A breadboard demonstrator of a novel UV/VIS grating spectrometer has been developed based upon a concentric arrangement of a spherical meniscus lens, concave spherical mirror and curved diffraction grating suitable for a range of atmospheric remote sensing applications from the ground or space. The spectrometer is compact and provides high optical efficiency and performance benefits over traditional instruments. The concentric design is capable of handling high relative apertures, owing to spherical aberration and comma being near zero at all surfaces. The design also provides correction for transverse chromatic aberration and distortion, in addition to correcting for the distortion called "smile", the curvature of the slit image formed at each wavelength. These properties render this design capable of superior spectral and spatial performance with size and weight budgets significantly lower than standard configurations. This form of spectrometer design offers the potential for exceptionally compact instrument for differential optical absorption spectroscopy (DOAS) applications from LEO, GEO, HAP or ground-based platforms. The breadboard demonstrator has been shown to offer high throughput and a stable Gaussian line shape with a spectral range from 300 to 450 nm at 0.5 nm resolution, suitable for a number of typical DOAS applications.

  16. Assessment of the performance of a compact concentric spectrometer system for Atmospheric Differential Optical Absorption Spectroscopy

    Directory of Open Access Journals (Sweden)

    C. Whyte

    2009-12-01

    Full Text Available A breadboard demonstrator of a novel UV/VIS grating spectrometer has been developed based upon a concentric arrangement of a spherical meniscus lens, concave spherical mirror and curved diffraction grating suitable for a range of atmospheric remote sensing applications from the ground or space. The spectrometer is compact and provides high optical efficiency and performance benefits over traditional instruments. The concentric design is capable of handling high relative apertures, owing to spherical aberration and comma being near zero at all surfaces. The design also provides correction for transverse chromatic aberration and distortion, in addition to correcting for the distortion called "smile", the curvature of the slit image formed at each wavelength. These properties render this design capable of superior spectral and spatial performance with size and weight budgets significantly lower than standard configurations. This form of spectrometer design offers the potential for exceptionally compact instrument for differential optical absorption spectroscopy (DOAS applications from LEO, GEO, HAP or ground-based platforms. The breadboard demonstrator has been shown to offer high throughput and a stable Gaussian line shape with a spectral range from 300 to 450 nm at 0.5 nm resolution, suitable for a number of typical DOAS applications.

  17. Evaluation of the bioavailability of major withanolides of Withania somnifera using an in vitro absorption model system.

    Science.gov (United States)

    Devkar, Santosh T; Kandhare, Amit D; Sloley, Brian D; Jagtap, Suresh D; Lin, James; Tam, Yun K; Katyare, Surendra S; Bodhankar, Subhash L; Hegde, Mahabaleshwar V

    2015-01-01

    Withania somnifera (L.) Dunal, shows several pharmacological properties which are attributed mainly to the withanolides present in the root. The efficacy of medicinally active withanolides constituents depends on the absorption and transportation through the intestinal epithelium. We examined these characteristics by employing the Sino-Veda Madin-Darby canine kidney cells culture system, which under in vitro condition shows the absorption characteristics similar to the human intestinal epithelium. Thus, the aim of the present investigation was to assess the bioavailability of individual withanolides. Withanolides were diluted in Hank's buffered saline at a concentration of 2 μg/ml were tested for permeability studies carried out for 1 h duration. Permeability was measured in terms of efflux pump (P eff) in cm/s. P eff values of withanolide A (WN A), withanone (WNN), 1,2-deoxywithastramonolide (1,2 DWM), withanolide B (WN B), withanoside IV-V (WS IV-V), and withaferin A were 4.05 × 10(-5), 2.06 × 10(-5), 1.97 × 10(-5), 1.80 × 10(-5), 3.19 × 10(-6), 3.03 × 10(-6) and 3.30 × 10(-7) respectively. In conclusion, the nonpolar and low molecular weight compounds (WN A, WNN, 1,2 DWM, and WN B) were highly permeable. As against this, the glycosylated and polar WS IV and WS V showed low permeability. Surprisingly and paradoxically, the highly biologically active withaferin A was completely impermeable, suggesting that further studies possibly using human epithelial colorectal adenocarcinoma (Caco-2) cells may be needed to delineate the absorption characteristics of withanolides, especially withaferin A.

  18. Mechanism of enhanced oral absorption of morin by phospholipid complex based self-nanoemulsifying drug delivery system.

    Science.gov (United States)

    Zhang, Jinjie; Li, Jianbo; Ju, Yuan; Fu, Yao; Gong, Tao; Zhang, Zhirong

    2015-02-02

    Phospholipid complex (PLC) based self-nanoemulsifying drug delivery system (PLC-SNEDDS) has been developed for efficient delivery of drugs with poor solubility and low permeability. In the present study, a BCS class IV drug and a P-glycoprotein (P-gp) substrate, morin, was selected as the model drug to elucidate the oral absorption mechanism of PLC-SNEDDS. PLC-SNEDDS was superior to PLC in protecting morin from degradation by intestinal enzymes in vitro. In situ perfusion study showed increased intestinal permeability by PLC was duodenum-specific. In contrast, PLC-SNEDDS increased morin permeability in all intestinal segments and induced a change in the main absorption site of morin from colon to ileum. Moreover, ileum conducted the lymphatic transport of PLC-SNEDDS, which was proven by microscopic intestinal visualization of Nile red labeled PLC-SNEDDS and lymph fluids in vivo. Low cytotoxicity and increased Caco-2 cell uptake suggested a safe and efficient delivery of PLC-SNEDDS. The increased membrane fluidity and disrupted actin filaments were closely associated with the increased cell uptake of PLC-SNEDDS. PLC-SNEDDS could be internalized into enterocytes as an intact form in a cholesterol-dependent manner via clathrin-mediated endocytosis and macropinocytosis. The enhanced oral absorption of morin was attributed to the P-gp inhibition by Cremophor RH and the intact internalization of M-PLC-SNEDDS into Caco-2 cells bypassing P-gp recognition. Our findings thus provide new insights into the development of novel nanoemulsions for poorly absorbed drugs.

  19. A static investigation of the thrust vectoring system of the F/A-18 high-alpha research vehicle

    Science.gov (United States)

    Mason, Mary L.; Capone, Francis J.; Asbury, Scott C.

    1992-01-01

    A static (wind-off) test was conducted in the static test facility of the Langley 16-foot Transonic Tunnel to evaluate the vectoring capability and isolated nozzle performance of the proposed thrust vectoring system of the F/A-18 high alpha research vehicle (HARV). The thrust vectoring system consisted of three asymmetrically spaced vanes installed externally on a single test nozzle. Two nozzle configurations were tested: A maximum afterburner-power nozzle and a military-power nozzle. Vane size and vane actuation geometry were investigated, and an extensive matrix of vane deflection angles was tested. The nozzle pressure ratios ranged from two to six. The results indicate that the three vane system can successfully generate multiaxis (pitch and yaw) thrust vectoring. However, large resultant vector angles incurred large thrust losses. Resultant vector angles were always lower than the vane deflection angles. The maximum thrust vectoring angles achieved for the military-power nozzle were larger than the angles achieved for the maximum afterburner-power nozzle.

  20. The grand partition function Z ({alpha},{beta}) of a quantum system is studied, using diagrammatic representations of the perturbation expansion; La grande fonction de partition Z ({alpha},{beta}) d'un systeme quantique est etudies en utilisant des representations diagrammatiques du developpement en serie des perturbations

    Energy Technology Data Exchange (ETDEWEB)

    Dominicis, C. de [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1961-07-01

    The grand partition function Z ({alpha},{beta}) of a quantum system is studied, using diagrammatic representations of the perturbation expansion. For a fermions system, it is possible to show, by proper resummation, without approximations but under some 'regularity hypothesis', that Log Z ({alpha},{beta}) takes a form where, besides trivial dependences, {alpha} and {beta} only appear through a statistical factor F{sub k}{sup -} = [1 + e{sup -{alpha}}{sup +{beta}}{sup {epsilon}{sub k}{sup 0}}{sup -{beta}}{sup W{sub k}}]{sup -1}. W{sub k} is a (real) self-consistent potential, generalized to all orders and can be defined by a stationary condition on Log Z ({alpha},{beta}) under variations of F{sub k}{sup -}. The thermodynamical quantities take a form analogous to the expressions Landau introduced for the Fermi liquids. The zero temperature limit (for isotropic systems) gives back Goldstone expressions for the ground state of a system. (author) [French] La grande fonction de partition Z ({alpha},{beta}) d'un systeme quantique est etudiee en utilisant des representations diagrammatiques du developpement en serie des perturbations. Pour un systeme de fermions on peut, par des resommations adequates, sans approximations mais sous reserve d'une 'hypothese de regularite', mettre Log Z ({alpha},{beta}) sous une forme ou, en dehors de dependances triviales, {alpha} et {beta} n'interviennent que par l'intermediaire d'un facteur statistique F{sub k}{sup -} = [1 + e{sup -{alpha}}{sup +{beta}}{sup {epsilon}{sub k}{sup 0}}{sup -{beta}}{sup W{sub k}}]{sup -1}. W{sub k} est ici un potentiel self-consistant (reel) generalise a tous les ordres et peut etre defini par une condition de stationnarite de Log Z ({alpha},{beta}) pour des variations de F{sub k}{sup -}. Les grandeurs thermodynamiques prennent une forme analogue aux expressions que LANDAU a introduites pour les liquides de FERMI. A la limite de la temperature nulle (et pour un

  1. The grand partition function Z ({alpha},{beta}) of a quantum system is studied, using diagrammatic representations of the perturbation expansion; La grande fonction de partition Z ({alpha},{beta}) d'un systeme quantique est etudies en utilisant des representations diagrammatiques du developpement en serie des perturbations

    Energy Technology Data Exchange (ETDEWEB)

    Dominicis, C de [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1961-07-01

    The grand partition function Z ({alpha},{beta}) of a quantum system is studied, using diagrammatic representations of the perturbation expansion. For a fermions system, it is possible to show, by proper resummation, without approximations but under some 'regularity hypothesis', that Log Z ({alpha},{beta}) takes a form where, besides trivial dependences, {alpha} and {beta} only appear through a statistical factor F{sub k}{sup -} = [1 + e{sup -{alpha}}{sup +{beta}}{sup {epsilon}{sub k}{sup 0}}{sup -{beta}}{sup W{sub k}}]{sup -1}. W{sub k} is a (real) self-consistent potential, generalized to all orders and can be defined by a stationary condition on Log Z ({alpha},{beta}) under variations of F{sub k}{sup -}. The thermodynamical quantities take a form analogous to the expressions Landau introduced for the Fermi liquids. The zero temperature limit (for isotropic systems) gives back Goldstone expressions for the ground state of a system. (author) [French] La grande fonction de partition Z ({alpha},{beta}) d'un systeme quantique est etudiee en utilisant des representations diagrammatiques du developpement en serie des perturbations. Pour un systeme de fermions on peut, par des resommations adequates, sans approximations mais sous reserve d'une 'hypothese de regularite', mettre Log Z ({alpha},{beta}) sous une forme ou, en dehors de dependances triviales, {alpha} et {beta} n'interviennent que par l'intermediaire d'un facteur statistique F{sub k}{sup -} = [1 + e{sup -{alpha}}{sup +{beta}}{sup {epsilon}{sub k}{sup 0}}{sup -{beta}}{sup W{sub k}}]{sup -1}. W{sub k} est ici un potentiel self-consistant (reel) generalise a tous les ordres et peut etre defini par une condition de stationnarite de Log Z ({alpha},{beta}) pour des variations de F{sub k}{sup -}. Les grandeurs thermodynamiques prennent une forme analogue aux expressions que LANDAU a introduites pour les liquides de FERMI. A la limite de la temperature nulle (et pour un systeme isotrope) on retrouve terme a terme les

  2. Absorption Spectrum and Density of States of Square, Rectangular, and Triangular Frenkel Exciton Systems with Gaussian Diagonal Disorder

    Directory of Open Access Journals (Sweden)

    Ibrahim Avgin

    2017-01-01

    Full Text Available Using the coherent potential approximation, we investigate the effects of disorder on the optical absorption and the density of states of Frenkel exciton systems on square, rectangular, and triangular lattices with nearest-neighbor interactions and a Gaussian distribution of transition energies. The analysis is based on an elliptic integral approach that gives results over the entire spectrum. The results for the square lattice are in good agreement with the finite-array calculations of Schreiber and Toyozawa. Our findings suggest that the coherent potential approximation can be useful in interpreting the optical properties of two-dimensional systems with dominant nearest-neighbor interactions and Gaussian diagonal disorder provided the optically active states are Frenkel excitons.

  3. Water quality - Measurement of gross alpha activity in non-saline water - Thick source method. 2. ed.

    International Nuclear Information System (INIS)

    2007-01-01

    This International Standard specifies a method for the determination of gross alpha activity in non-saline waters for alpha-emitting radionuclides which are not volatile at 350 degree Centigrade. It is possible to determine supported volatile radionuclides measured to an extent determined by half-life, matrix retention (of the volatile species) and the duration of measurement (counting time). The method is applicable to raw and potable waters. The range of application depends on the amount of suspended matter in the water and on the performance characteristics (background count rate and counting efficiency) of the counter. Gross alpha radioactivity is determined by using proportional counting or solid scintillation counting on water residue deposited on a planchet. Due to the strong absorption of the residue deposit, it is considered that the alpha emission from the surface is proportional to the alpha activity of the deposit. Gross alpha determination is not an absolute determination of the sample alpha radioactive content, but a relative determination referring to a specific alpha emitter which constitutes the standard calibration source. This type of determination is also known as alpha index. The sample is acidified to stabilize it, evaporated almost to dryness, converted to the sulfate form and then ignited at 350 degree Centigrade. A portion of the residue is transferred to a planchet and the alpha activity measured by counting in an alpha-particle detector or counting system previously calibrated against an alpha-emitting standard and the alpha activity concentration calculated. The paper provides information about scope, normative references, symbols, definitions and units, principle, reagents and equipment, procedure, contamination check, expression of results and test report

  4. Design and construction of a system for determining Radon-222 through Alpha spectroscopy; Diseno y construccion de un sistema para determinar Radon-222 mediante Espectroscopia alfa

    Energy Technology Data Exchange (ETDEWEB)

    Bonifacio, J.; Iturbe, J.L

    1992-02-15

    The study of the present work consists on designing a system to measure gas {sup 222} Rn, using a surface barrier detector, in order to obtaining a more accuracy measure of this isotope by means of an alpha particle spectra and thus to try to avoid the influence of the radioactivity of the isotope descendants of short half life, which are also emitting of alpha particles, since by other methods its should make a series of corrections to obtain the real value of the radon activity. (Author)

  5. Probing slowly exchanging protein systems via {sup 13}C{sup {alpha}}-CEST: monitoring folding of the Im7 protein

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Alexandar L.; Bouvignies, Guillaume; Kay, Lewis E., E-mail: kay@pound.med.utoronto.ca [University of Toronto, Departments of Molecular Genetics, Biochemistry and Chemistry (Canada)

    2013-03-15

    A {sup 13}C{sup {alpha}} chemical exchange saturation transfer based experiment is presented for the study of protein systems undergoing slow interconversion between an 'observable' ground state and one or more 'invisible' excited states. Here a labeling strategy whereby [2-{sup 13}C]-glucose is the sole carbon source is exploited, producing proteins with {sup 13}C at the C{sup {alpha}} position, while the majority of residues remain unlabeled at CO or C{sup {beta}}. The new experiment is demonstrated with an application to the folding reaction of the Im7 protein that involves an on-pathway excited state. The obtained excited state {sup 13}C{sup {alpha}} chemical shifts are cross validated by comparison to values extracted from analysis of CPMG relaxation dispersion profiles, establishing the utility of the methodology.

  6. Demonstration of an on-site PAFC cogeneration system with waste heat utilization by a new gas absorption chiller

    Energy Technology Data Exchange (ETDEWEB)

    Urata, Tatsuo [Tokyo Gas Company, LTD, Tokyo (Japan)

    1996-12-31

    Analysis and cost reduction of fuel cells is being promoted to achieve commercial on-site phosphoric acid fuel cells (on-site FC). However, for such cells to be effectively utilized, a cogeneration system designed to use the heat generated must be developed at low cost. Room heating and hot-water supply are the most simple and efficient uses of the waste heat of fuel cells. However, due to the short room-heating period of about 4 months in most areas in Japan, the sites having demand for waste heat of fuel cells throughout the year will be limited to hotels and hospitals Tokyo Gas has therefore been developing an on-site FC and the technology to utilize tile waste heat of fuel cells for room cooling by means of an absorption refrigerator. The paper describes the results of fuel cell cogeneration tests conducted on a double effect gas absorption chiller heater with auxiliary waste heat recovery (WGAR) that Tokyo Gas developed in its Energy Technology Research Laboratory.

  7. Detection of gastrointestinal cancer by elastic scattering and absorption spectroscopies with the Los Alamos Optical Biopsy System

    Energy Technology Data Exchange (ETDEWEB)

    Mourant, J.R.; Boyer, J.; Johnson, T.M.; Lacey, J.; Bigio, I.J. [Los Alamos National Lab., NM (United States); Bohorfoush, A. [Wisconsin Medical School, Milwaukee, WI (United States). Dept. of Gastroenterology; Mellow, M. [Univ. of Oklahoma Medical School, Oklahoma City, OK (United States). Dept. of Gastroenterology

    1995-03-01

    The Los Alamos National Laboratory has continued the development of the Optical Biopsy System (OBS) for noninvasive, real-time in situ diagnosis of tissue pathologies. In proceedings of earlier SPIE conferences we reported on clinical measurements in the bladder, and we report here on recent results of clinical tests in the gastrointestinal tract. With the OBS, tissue pathologies are detected/diagnosed using spectral measurements of the elastic optical transport properties (scattering and absorption) of the tissue over a wide range of wavelengths. The use of elastic scattering as the key to optical tissue diagnostics in the OBS is based on the fact that many tissue pathologies, including a majority of cancer forms, exhibit significant architectural changes at the cellular and sub-cellular level. Since the cellular components that cause elastic scattering have dimensions typically on the order of visible to near-IR wavelengths, the elastic (Mie) scattering properties will be wavelength dependent. Thus, morphology and size changes can be expected to cause significant changes m an optical signature that is derived from the wavelength-dependence of elastic scattering. Additionally, the optical geometry of the OBS beneficially enhances its sensitivity for measuring absorption bands. The OBS employs a small fiber-optic probe that is amenable to use with any endoscope or catheter, or to direct surface examination, as well as interstitial needle insertion. Data acquistion/display time is <1 second.

  8. In operando observation system for electrochemical reaction by soft X-ray absorption spectroscopy with potential modulation method

    International Nuclear Information System (INIS)

    Nagasaka, Masanari; Kosugi, Nobuhiro; Yuzawa, Hayato; Horigome, Toshio

    2014-01-01

    In order to investigate local structures of electrolytes in electrochemical reactions under the same scan rate as a typical value 100 mV/s in cyclic voltammetry (CV), we have developed an in operando observation system for electrochemical reactions by soft X-ray absorption spectroscopy (XAS) with a potential modulation method. XAS spectra of electrolytes are measured by using a transmission-type liquid flow cell with built-in electrodes. The electrode potential is swept with a scan rate of 100 mV/s at a fixed photon energy, and soft X-ray absorption coefficients at different potentials are measured at the same time. By repeating the potential modulation at each fixed photon energy, it is possible to measure XAS of electrochemical reaction at the same scan rate as in CV. We have demonstrated successful measurement of the Fe L-edge XAS spectra of aqueous iron sulfate solutions and of the change in valence of Fe ions at different potentials in the Fe redox reaction. The mechanism of these Fe redox processes is discussed by correlating the XAS results with those at different scan rates

  9. Development of a combination detector system for simultaneous measurement of Alpha and Beta/Gamma radioactivity

    International Nuclear Information System (INIS)

    Thakur, Vaishali M.; Ashokkumar, P.; Rekha, A.K.; Jain, Amit; Rath, D.P.; Chaudhury, Probal; Chaudhari, L.M.

    2018-01-01

    Analysis of various samples for α and β/γ radioactivity is carried out in radiological laboratories. Using independent α and β/γ counting systems such measurements are done separately for same sample. In order to address the requirement of simultaneous measurement of α and β/γ activity content of radioactive samples, a counting system using combination of two detectors has been developed. Activity deposited on a 2 mm deep 30 mm diameter aluminum planchette was counted under the detector combination consisting of a ZnS(Ag) and plastic scintillator for α and β/γ respectively. The design and fabrication of the combination detector, development of electronics associated with the system, its characterization and application are presented here

  10. Comment on resonant absorption

    International Nuclear Information System (INIS)

    Hammerling, P.

    1977-01-01

    An average over angles of incidence of the usual resonant absorption function is presented. This form is appropriate under experimental conditions where the angles of incidence vary greatly and in an unknown manner. For comparison a lens-ellipsoidal mirror illumination system with a known longitudinal aberration is considered. In the latter example the angles of incidence are readily obtained and the resulting resonance absorption function evaluated. The associated fields are calculated in a similar fashion. (author)

  11. Systemic use of tumor necrosis factor alpha as an anticancer agent

    Science.gov (United States)

    Roberts, Nicholas J.; Zhou, Shibin; Diaz, Luis A.; Holdhoff, Matthias

    2011-01-01

    Tumor necrosis factor-α (TNF-α) has been discussed as a potential anticancer agent for many years, however initial enthusiasm about its clinical use as a systemic agent was curbed due to significant toxicities and lack of efficacy. Combination of TNF-α with chemotherapy in the setting of hyperthermic isolated limb perfusion (ILP), has provided new insights into a potential therapeutic role of this agent. The therapeutic benefit from TNF-α in ILP is thought to be not only due to its direct anti-proliferative effect, but also due to its ability to increase penetration of the chemotherapeutic agents into the tumor tissue. New concepts for the use of TNF-α as a facilitator rather than as a direct actor are currently being explored with the goal to exploit the ability of this agent to increase drug delivery and to simultaneously reduce systemic toxicity. This review article provides a comprehensive overview on the published previous experience with systemic TNF-α. Data from 18 phase I and 10 phase II single agent as well as 18 combination therapy studies illustrate previously used treatment and dose schedules, response data as well as the most prominently observed adverse effects. Also discussed, based on recent preclinical data, is a potential future role of systemic TNF-α in combination with liposomal chemotherapy to facilitate increased drug uptake into tumors. PMID:22036896

  12. An antiaging skin care system containing alpha hydroxy acids and vitamins improves the biomechanical parameters of facial skin.

    Science.gov (United States)

    Tran, Diana; Townley, Joshua P; Barnes, Tanya M; Greive, Kerryn A

    2015-01-01

    The demand for antiaging products has dramatically increased in recent years, driven by an aging population seeking to maintain the appearance of youth. This study investigates the effects of an antiaging skin care system containing alpha hydroxy acids (AHAs) in conjunction with vitamins B3, C, and E on the biomechanical parameters of facial skin. Fifty two volunteers followed an antiaging skin care regimen comprising of cleanser, eye cream, day moisturizer, and night moisturizer for 21 days. Wrinkle depth (Ry ) and skin roughness (Ra ) were measured by skin surface profilometry of the crow's feet area, and skin elasticity parameters R2 (gross elasticity), R5 (net elasticity), R6 (viscoelastic portion), and R7 (recovery after deformation) were determined for facial skin by cutometer, preapplication and after 7, 14, and 21 days. Volunteers also completed a self-assessment questionnaire. Compared to baseline, Ry and Ra significantly improved by 32.5% (Pskin care treatment. These results were observed by the volunteers with 9 out of 10 discerning an improvement in skin texture and smoothness. Compared to baseline, R2 and R5 significantly increased by 15.2% (Pskin care system containing AHAs and vitamins significantly improves the biomechanical parameters of the skin including wrinkles and skin texture, as well as elasticity without significant adverse effects.

  13. NIR and MR imaging supported hydrogel based delivery system for anti-TNF alpha probiotic therapy of IBD

    Science.gov (United States)

    Janjic, Jelena M.; Berlec, Ales; Bagia, Christina; Liu, Lu S.; Jeric, Irenej; Gach, Michael; Janjic, Bratislav M.; Strukelj, Borut

    2016-03-01

    Current treatment of inflammatory bowel disease (IBD) is largely symptomatic and consists of anti-inflammatory agents, immune-suppressives or antibiotics, whereby local luminal action is preferred to minimize systemic side-effects. Recently, anti-TNFα therapy has shown considerable success and is now being routinely used. Here we present a novel approach of using perfluorocarbon (PFC) nanoemulsion containing hydrogels (nanoemulgels) as imaging supported delivery systems for anti-TNF alpha probiotic delivery in IBD. To further facilitate image-guided therapy a food-grade lactic acid bacterium Lactococcus lactis capable of TNFα-binding was engineered to incorporate infrared fluorescent protein (IRFP). This modified bacteria was then incorporated into novel PFC nanoemulgels. The nanoemulgels presented here are designed to deliver locally anti-TNFα probiotic in the lower colon and rectum and provide dual imaging signature of gel delivery (MRI) across the rectum and lower colon and bacteria release (NIR). NIR imaging data in vitro demonstrates high IRFP expressing and TNFα-binding bacteria loading in the hydrogel and complete release in 3 hours. Stability tests indicate that gels remain stable for at least 14 days showing no significant change in droplet size, zeta potential and pH. Flow cytometry analyses demonstrate the NIRF expressing bacteria L. lactis binds TNFα in vitro upon release from the gels. Magnetic resonance and near-infrared imaging in vitro demonstrates homogeneity of hydrogels and the imaging capacity of the overall formulation.

  14. Characterization of the EPRI Differential Absorption Lidar (DIAL) System. Final report. [For remote sensing of air pollutants

    Energy Technology Data Exchange (ETDEWEB)

    Baumgartner, R.A.; Depp, J.G.; Evans, W.E.; Grant, W.B.; Hawley, J.G.; March, R.G.; Murray, E.R.; Proctor, E.K.

    1979-12-01

    SRI International designed and constructed a DIfferential Absorption Lidar (DIAL) to provide EPRI with a mobile field system for remote measurements of SO/sub 2/, NO/sub 3/, and O/sub 3/. After field testing the lidar was prepared for the sytem calibration testing where lidar measurements were compared to in situ profiles of SO/sub 2/, NO/sub 2/, and O/sub 3/. This two-week field program determined overall system accuracy and reliability in measuring varying ambient gas concentrations. The lidar was then returned to SRI for detailed subsystem performance evaluations. Improvements were made wherever possible, and the lidar was prepared for further systems tests. Tests were made using an NO/sub 2/ sample chamber to simulate a calibrated NO/sub 2/ plume, and ambient measured NO/sub 2/ concentrations were compared with values from a regional air pollutant monitoring station. Following the local calibration and the systems field tests, SRI evaluated the performance and reliability of the EPRI lidar. Based on that evaluation, SRI undertook a major analysis of possible system improvements. Although the remote measuring capability had been successfully demonstrated in the field program, SRI makes several recommendations for systems improvements which would increase the lidar accuracy and reliability.

  15. Development of the Hybrid Operation Method of a Multi-Geothermal Heat Pump System and Absorption Chiller-Heater

    Directory of Open Access Journals (Sweden)

    Young-Ju Jung

    2015-08-01

    Full Text Available Considerable efforts have been made to reduce the energy consumption of buildings due to the energy crisis, and, the Korean government has supported the use of renewable energy through various grants. Among the possible renewable energy sources, geothermal energy can be used regardless of the outside weather. Therefore, energy consumption can be reduced considerably in summer and winter. Despite the increasing use of renewable energy, the use of renewables has not been operating appropriately. Therefore, this study examined some of the problems of the operation of renewable energy and some possible improvements. The aim of the study is to evaluate a building containing an actual installed multi-geothermal heat pump (Multi-GHP system, in terms of the energy efficiency. In addition, this study evaluated the present control system and the method of complex operation regarding existing heat sources systems and GHP systems through a simulation. The results can be regarded as the result of a hybrid operation method for the improvement of an existing operation. Therefore, the Multi-GHP system energy use of a hybrid operation condition of the Multi-GHP systems and the absorption (ABS chiller-heater system was reduced compared to the operation condition of the Multi-GHP system, and the total energy consumption of the heat source equipment was reduced. The proposed operation plan was evaluated after applying the system to a building. These results showed that the efficient operation of a Multi-GHP hybrid operation method is possible. As a result, the GHP energy use of Multi-GHP systems and the ABS chiller-heater system was reduced by 30% compared to existing operation and the total energy consumption of heat source equipment was reduced by 78%.

  16. Some comments about the comparison between a conventional and a solar powered absorption refrigeration system

    International Nuclear Information System (INIS)

    Corbella, O.D.; Garibotti, C.R.

    1983-08-01

    Two statements about the performance of solar refrigeration systems are discussed. First, concepts of efficiency and coefficient of performance are studied. Second, the influence of inflation and rise of fuel prices are considered, in relation to the comparison between solar and conventional refrigeration systems. (author)

  17. Applications of some microscopic, diffraction and absorption techniques to the study of metal--hydrogen systems

    International Nuclear Information System (INIS)

    Pick, M.A.

    1979-01-01

    Several experimental techniques were reviewed which are used to investigate metal hydrogen systems. The first technique is metallography and optical microscopy. This is a very old technique which was found to be very powerful in the case of metal hydrogen systems. A few examples of such work are shown and the results are discussed

  18. In Vitro-In Vivo Predictive Dissolution-Permeation-Absorption Dynamics of Highly Permeable Drug Extended-Release Tablets via Drug Dissolution/Absorption Simulating System and pH Alteration.

    Science.gov (United States)

    Li, Zi-Qiang; Tian, Shuang; Gu, Hui; Wu, Zeng-Guang; Nyagblordzro, Makafui; Feng, Guo; He, Xin

    2018-05-01

    Each of dissolution and permeation may be a rate-limiting factor in the absorption of oral drug delivery. But the current dissolution test rarely took into consideration of the permeation property. Drug dissolution/absorption simulating system (DDASS) valuably gave an insight into the combination of drug dissolution and permeation processes happening in human gastrointestinal tract. The simulated gastric/intestinal fluid of DDASS was improved in this study to realize the influence of dynamic pH change on the complete oral dosage form. To assess the effectiveness of DDASS, six high-permeability drugs were chosen as model drugs, including theophylline (pK a1  = 3.50, pK a2  = 8.60), diclofenac (pK a  = 4.15), isosorbide 5-mononitrate (pK a  = 7.00), sinomenine (pK a  = 7.98), alfuzosin (pK a  = 8.13), and metoprolol (pK a  = 9.70). A general elution and permeation relationship of their commercially available extended-release tablets was assessed as well as the relationship between the cumulative permeation and the apparent permeability. The correlations between DDASS elution and USP apparatus 2 (USP2) dissolution and also between DDASS permeation and beagle dog absorption were developed to estimate the predictability of DDASS. As a result, the common elution-dissolution relationship was established regardless of some variance in the characteristic behavior between DDASS and USP2 for drugs dependent on the pH for dissolution. Level A in vitro-in vivo correlation between DDASS permeation and dog absorption was developed for drugs with different pKa. The improved DDASS will be a promising tool to provide a screening method on the predictive dissolution-permeation-absorption dynamics of solid drug dosage forms in the early-phase formulation development.

  19. Multitracer study on absorption of radionuclides in atmosphere-plant system

    International Nuclear Information System (INIS)

    Ambe, Shizuko; Shinonaga, Taeko; Watanabe, Tadakazu; Yamaguchi, Isamu

    1996-01-01

    Direct absorption of atmospheric radionuclides by soybean plants was studied using a radioactive multitracer consisting of radionuclides of Sc, Mn, Co, As, Se, Rb, Sr, Y, Eu, Gd, Yb, Hf, Re, and Ir. Soybean seedlings were cultivated at 23degC in a box where multitracer-adsorbed cellulose powders were floating in air. After 28-49 day-cultivation, the plants were harvested and divided into beans (seeds and pods), leaves, stems (inside and outside), and roots. Beans or leaves originating from the same node were collected together. After washing with dilute HCl solution and distilled water, they were dried and then subjected to γ-ray measurement. It was estimated that about 0.2 % of the multitracer was absorbed by the soybean plant, of which 80 % was found in the leaves, and 10 % each in beans and stems. The relative amounts of elements in the beans, leaves, and stems markedly differed depending on the element. Among the elements, Se * was greatly accumulated in the beans, leaves, and stems. Cobalt * , Se * , and Rb * were dominant in the beans, especially in the edible part of seeds. Relative amounts of Mn * , As * , Sr * , and Re * in the seeds were very small. It is noticeable that these nuclides were found in the seeds, though they were not physically exposed to the multitracer-adsorbed cellulose powders during growth. The radioactivities of Sc * , Mn * , Co * , As * , Se * , Rb * , Sr * , Y * , Eu * , Gd * , Yb * , Hf * , Re * , and Ir * were observed for the leaves. Brown leaves accumulated greater amounts of radionuclides than green ones. Main nuclides found in the stem were Sc * , Co * , Se * , Y * , Eu * , Gd * , Yb * , Hf * , and Ir * , a larger part of them on the outside. Trace amounts of Co * , Se * , and Rb * were detected in the roots. Little leakage of the multitracer into the soil was observed. These results indicate that various radionuclides in the atmosphere were directly absorbed through soybean leaves and then transported to the edible part

  20. Balance carried out on an alpha waste incinerator in order to qualify its filtration system

    International Nuclear Information System (INIS)

    Cartier, R.; Burghofer, P.; Tregoures, A.; Maurel, J.M.; Vendel, J.

    1991-01-01

    A balance was carried out on a pilot incinerator of inactive solid waste running at 4 kg/h. Various measurements were taken in order to qualify the prefiltration system of the incineration process operating by pyrolysis, afterburning and calcination: determining the ventilation characteristics of the plant (gas flow rates and residence time) and the physico-chemical characteristics of the effluent (mass flow and granulometric range of particles, chemical composition of gases). Various methods of sampling and of analyzing the gases were adopted and a thermochemical model was produced. Its results are reasonably close to the experimental measurements. The emission consists of submicronic particles and porous layers are the best adapted cleaning system

  1. Fully automated system for Pu measurement by gamma spectrometry of alpha contaminated solid wastes

    International Nuclear Information System (INIS)

    Cresti, P.

    1986-01-01

    A description is given of a fully automated system developed at Comb/Mepis Laboratories which is based on the detection of specific gamma signatures of Pu isotopes for monitoring Pu content in 15-25 l containers of low density (0.1 g/cm 3 ) wastes. The methodological approach is discussed; based on experimental data, an evaluation of the achievable performances (detection limit, precision, accuracy, etc.) is also given

  2. Experimental system using an active method for the measurement of low alpha emitter grades

    International Nuclear Information System (INIS)

    Bernard, P.; Cance, M.

    1986-06-01

    The diversity of waste produced in France, the limitations of passive neutron measurements, the new safety requirements in the field of low level waste disposal have induced us to develop active neutron techniques. Two experimental pulsed neutron interrogation systems are described giving a sensitivity lower than 10 mg Pu 239 in 200 l drums. This project is the result of a close cooperation between the CEA, SGN and SODERN

  3. Narrative absorption

    DEFF Research Database (Denmark)

    Narrative Absorption brings together research from the social sciences and Humanities to solve a number of mysteries: Most of us will have had those moments, of being totally absorbed in a book, a movie, or computer game. Typically we do not have any idea about how we ended up in such a state. No...

  4. Conserved ABC Transport System Regulated by the General Stress Response Pathways of Alpha- and Gammaproteobacteria

    Energy Technology Data Exchange (ETDEWEB)

    Herrou, Julien; Willett, Jonathan W.; Czy; #380; , Daniel M.; Babnigg, Gyorgy; Kim, Youngchang; Crosson, Sean (UC)

    2016-12-19

    ABSTRACT

    Brucella abortusσE1is an EcfG family sigma factor that regulates the transcription of dozens of genes in response to diverse stress conditions and is required for maintenance of chronic infection in a mouse model. A putative ATP-binding cassette transporter operon,bab1_0223-bab1_0226, is among the most highly activated gene sets in the σE1regulon. The proteins encoded by the operon resemble quaternary ammonium-compatible solute importers but are most similar in sequence to the broadly conserved YehZYXW system, which remains largely uncharacterized. Transcription ofyehZYXWis activated by the general stress sigma factor σSinEnterobacteriaceae, which suggests a functional role for this transport system in bacterial stress response across the classesAlphaproteobacteriaandGammaproteobacteria. We present evidence thatB. abortusYehZYXW does not function as an importer of known compatible solutes under physiological conditions and does not contribute to the virulence defect of a σE1-null strain. The solein vitrophenotype associated with genetic disruption of this putative transport system is reduced growth in the presence of high Li+ion concentrations. A crystal structure ofB. abortusYehZ revealed a class II periplasmic binding protein fold with significant structural homology toArchaeoglobus fulgidusProX, which binds glycine betaine. However, the structure

  5. Proposed development programme for a temporary containment system for alpha active decommissioning

    International Nuclear Information System (INIS)

    Pengelly, M.G.A.; Burnett, R.C.

    1983-06-01

    This report makes a proposal to design, develop and test a containment of modular construction under plutonium active conditions. While this proposal contemplates work with plutonium, the system, when fully developed, has obvious applications wherever a temporary containment of radioactive or toxic materials is required. The fundamental feature of the proposal is that strippable coatings are used to prevent the inner surfaces of the working area from becoming contaminated. It is envisaged that this method of protecting the surfaces will enable the modular containment structure to be disassembled and re-used. (author)

  6. Configuration optimization of series flow double-effect water-lithium bromide absorption refrigeration systems by cost minimization

    DEFF Research Database (Denmark)

    Mussati, Sergio F.; Cignitti, Stefano; Mansouri, Seyed Soheil

    2018-01-01

    An optimal process configuration for double-effect water-lithium bromide absorption refrigeration systems with series flow – where the solution is first passed through the high-temperature generator – is obtained by minimization of the total annual cost for a required cooling capacity. To this end......) takes place entirely at the high-temperature zone, and the sizes and operating conditions of the other process units change accordingly in order to meet the problem specification with the minimal total annual cost. This new configuration was obtained for wide ranges of the cooling capacity (150–450 k.......9%, respectively. Most importantly, the obtained optimal solution eliminates the low-temperature solution heat exchanger from the conventional configuration, rendering a new process configuration. The energy integration between the weak and strong lithium bromide solutions (cold and hot streams, respectively...

  7. Optimization study of a single-effect water–lithium bromide absorption refrigeration system powered by flat-plate collector in hot regions

    International Nuclear Information System (INIS)

    Saleh, A.; Mosa, M.

    2014-01-01

    Highlights: • A comprehensive analysis for optimizing solar absorption system in hot region. • The most important parameter to be controlled is hot source temperature. • Ensuring appropriate choice of parameters, COP of absorption unit exceeds 0.8. • Results show that solar cooling systems are promising in hot regions. • The research aims to play a vital role to promote the use of renewable energy. - Abstract: This investigation has been carried out to present a comprehensive analysis for optimizing the operation of solar absorption system in hot regions. To optimize performance of the system, the hot source temperature should be controlled in function of incident solar radiation, chilled and cooling water temperatures. With an appropriate control, these external conditions can be monitored to detect and implement the actual optimization conditions. Adopting typical values encountered in hot regions, the overall system performance takes its optimal value at temperatures between 75 and 80 °C. It was found that in designing or selecting solar collector, selective coating type is necessary to produce hot water with potential around 80–90 °C needed to optimize operation of absorption unit. By ensuring an appropriate choice of components temperatures, COP of absorption unit can exceed the value 0.8. Cooling water temperature above 40 °C reduces significantly the performance of the unit which requires, under conditions of extremely high external temperatures, dimensioning and selection of condensers and absorbers that guarantee values less than this limit

  8. Utilizing Near-IR Tunable Laser Absorption Spectroscopy to Study Detonation and Combustion Systems

    Science.gov (United States)

    2014-03-27

    A Hencken burner, Rotating Detonation Engine ( RDE ), and a detonation tube were studied using a Time-Devision Multiplexed Tunable Diode Laser...for the three systems. Velocity was calculated for the RDE system using the Doppler shift of the spectral lines. To perform the calculations necessary...however, the CH4 flame did not match as well. The exhaust of the RDE was studied at various equivalence ratios using a hydrogen-air mixture (H2-air

  9. Vibration energy absorption in the whole-body system of a tractor operator

    OpenAIRE

    Jan Szczepaniak; Wojciech Tanaś; Jacek Kromulski

    2014-01-01

    Many people are exposed to whole-body vibration (WBV) in their occupational lives, especially drivers of vehicles such as tractor and trucks. The main categories of effects from WBV are perception degraded comfort interference with activities-impaired health and occurrence of motion sickness. Absorbed power is defined as the power dissipated in a mechanical system as a result of an applied force. The vibration-induced injuries or disorders in a substructure of the human system are primari...

  10. A experimental system for the checking of the absorption of E.C.A.G. graphite; Empilement pour le controle du graphite E.C.A.G

    Energy Technology Data Exchange (ETDEWEB)

    Raievski, V; Vidal, R [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1958-07-01

    A system is described for measuring the mean absorption cross section in thermal neutrons of graphite. This system consists of a graphite stack containing a Ra-Be source and a BF3 counter. A cavity in the stack receives the graphite to be studied or the graphite standard. By comparing the counting rates their absorption ratio can be deduced. The measurement is performed on graphite rods which have been machined before being placed in the pile. It provides the possibility of detecting over a batch of 1 ton of graphite, in a single measurement, a difference in absorption of 0.1 milli barn. (author) [French] On decrit un dispositif permettant de mesurer la section efficace moyenne d'absorption en neutrons thermiques du graphite. Ce dispositif est constitue par un empilement de graphite contenant une source de Ra-Be et un compteur a BF3. Une cavite menagee dans l'empilement peut recevoir le graphite a etudier ou le graphite etalon. Par comparaison des taux de comptage, on en deduit leur rapport d'absorption. La mesure est effectuee sur des barres de graphite usinees avant leur mise en place dans la pile. Elle permet de deceler sur un lot de graphite de 1 tonne, en une seule mesure, une difference d'absorption de 0,1 millibarn. (auteur)

  11. Design of mini-multi-gas monitoring system based on IR absorption

    Energy Technology Data Exchange (ETDEWEB)

    Tan, Q.L.; Zhang, W.D.; Xue, C.Y.; Xiong, J.J.; Ma, Y.C.; Wen, F. [Northern University of China, Taiyuan (China)

    2008-07-15

    In this paper, a novel non-dispersive infrared ray (IR) gas detection system is described. Conventional devices typically include several primary components: a broadband source (usually all incandescent filament), a rotating chopper shutter, a narrow-band filter, a sample tube and a detector. But we mainly use file mini-multi-channel detector, electrical modulation means and mini-gas-cell structure. To solve the problems of gas accidents in coal mines, and for family safety that results from using gas, this new IR detection system with integration, miniaturization and non-moving parts has been developed. It is based on the principle that certain gases absorb infrared radiation at specific (and often unique) wavelengths. The infrared detection optics principle used in developing this system is mainly analyzed. The idea of multi-gas detection is introduced and guided through the analysis of the single-gas detection. Through researching the design of cell structure, a cell with integration and miniaturization has been devised. By taking a single-chip microcomputer (SCM) as intelligence handling, the functional block diagram of a gas detection system is designed with the analyzing and devising of its hardware and software system. The way of data transmission on a controller area network (CAN) bus and wireless data transmission mode is explained. This system has reached the technology requirement of lower power consumption, mini-volume, wide measure range, and is able to realize multi-gas detection.

  12. Establishment of the observing system for boron in steels by alpha-particle track etching method using JAERI reactor

    International Nuclear Information System (INIS)

    Asakura, Kentaro; Shibata, Koji; Sawahata, Hiroyuki; Kawate, Minoru; Harasawa, Susumu

    2003-01-01

    Alpha-particle track etching (ATE) method is most effective in observing boron distribution in steels. Previously, in Japan, neutron irradiation for this method was carried out in the reactor at the Institute of Atomic Energy, Rikkyo University. This reactor, however, was shut down in 1999. Therefore, the establishment of a new system for ATE method has been required and experimental research was performed using the reactor at the Japan Atomic Energy Research Institute (JAERI). It was clarified that the irradiation equipment for medical treatment of the reactor JRR-4 was most suitable for ATE method. The specimen trestle for low radioactive exposure was newly-developed. ATE image obtained by 12h irradiation using this trestle showed a good quality similar to that obtained using Rikkyo's reactor and that obtained using the trestle of the old model. Using this new trestle, the amount of neutron which the worker suffers during the operation at the irradiation equipment decreases from 4μSv/h to 0-1 μSv/h compared with the trestle of the old model. The total amount of thermal neutron after 12 h irradiation was almost same as that under the recommended condition of the reactor at Rikkyo University, 6.5 x 10 14 n cm -2 . (author)

  13. Stabilization and activation of alpha-chymotrypsin in water-organic solvent systems by complex formation with oligoamines.

    Science.gov (United States)

    Kudryashova, Elena V; Artemova, Tatiana M; Vinogradov, Alexei A; Gladilin, Alexander K; Mozhaev, Vadim V; Levashov, Andrey V

    2003-04-01

    Formation of enzyme-oligoamine complexes was suggested as an approach to obtain biocatalysts with enhanced resistance towards inactivation in water-organic media. Complex formation results in broadening (by 20-40% v/v ethanol) of the range of cosolvent concentrations where the enzyme retains its catalytic activity (stabilization effect). At moderate cosolvent concentrations (20-40% v/v) complex formation activates the enzyme (by 3-6 times). The magnitude of activation and stabilization effects increases with the number of possible electrostatic contacts between the protein surface and the molecules of oligoamines (OA). Circular dichroism spectra in the far-UV region show that complex formation stabilizes protein conformation and prevents aggregation in water-organic solvent mixtures. Two populations of the complexes with different thermodynamic stabilities were found in alpha-chymotrypsin (CT)-OA systems depending on the CT/OA ratio. The average dissociation constants and stoichiometries of both low- and high-affinity populations of the complexes were estimated. It appears that it is the low-affinity sites on the CT surface that are responsible for the activation effect.

  14. Operations of the thermal control system for Alpha Magnetic Spectrometer electronics following the beta angle of the International Space Station

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Kun; Li, Jinbo; Cui, Zheng; Wang, Naihua; Sun, Qie; Cheng, Lin, E-mail: cheng@sdu.edu.cn

    2014-12-11

    The Alpha Magnetic Spectrometer (AMS) has been running and measuring cosmic rays on the International Space Station (ISS) since May 19, 2011. The thermal control system (TCS) plays an important role in keeping all components and equipment working in an operational temperature range. Since the AMS started working on the ISS, AMS thermal engineers have been monitoring the on-orbit status of the TCS. During normal operation, the local temperature of AMS components regularly varies along with the β angle of the ISS. Based on the collected temperature data, the general characteristics of local temperature variations of TCS for AMS Electronics following the β of the ISS are discussed with the statistics of the orbit-averaged temperature and the orbit standard deviation of temperature. Furthermore some temperature anomalies at specific β are also studied. - Highlights: • The variation of the main radiators temperature is statistically analyzed. • The hot case and cold case for the main radiators are found in normal operations. • The solar illumination falling on the inner sheet of RAM radiator leads to temperature jump. • The temperature anomalies on the WAKE radiator show a uniform trend except WR3 sensor. • The regularity of the temperature variation is described with fitted equations.

  15. The effects of water absorption on an ester vinyl resin system

    Directory of Open Access Journals (Sweden)

    Ledjane Lima Sobrinho

    2009-09-01

    Full Text Available Derakene is a vinyl ester resin largely employed as matrix for polymeric based composite systems. In this work, the performance of such polymeric system was evaluated considering the effect of hygrothermal aging. The mechanical and thermal properties were examined for the processed material before and after ageing in water at 60 ºC for a maximum period of 64 days. Both analyses indicated the occurrence of post cure of the system after 16 days due to exposition at 60 ºC in water, which was also confirmed by analyses in samples with post cure treatment. Moreover, it was observed plasticizing of resin after 36 and 64 days of ageing. Micro structural and fracture surface analyses were carried out in order to characterize the samples. The appearance of surface voids was also observed.

  16. Förster resonance energy transfer, absorption and emission spectra in multichromophoric systems. II. Hybrid cumulant expansion.

    Science.gov (United States)

    Ma, Jian; Moix, Jeremy; Cao, Jianshu

    2015-03-07

    We develop a hybrid cumulant expansion method to account for the system-bath entanglement in the emission spectrum in the multi-chromophoric Förster transfer rate. In traditional perturbative treatments, the emission spectrum is usually expanded with respect to the system-bath coupling term in both real and imaginary time. This perturbative treatment gives a reliable absorption spectrum, where the bath is Gaussian and only the real-time expansion is involved. For the emission spectrum, the initial state is an entangled state of the system plus bath. Traditional perturbative methods are problematic when the excitations are delocalized and the energy gap is larger than the thermal energy, since the second-order expansion cannot predict the displacement of the bath. In the present method, the real-time dynamics is carried out by using the 2nd-order cumulant expansion method, while the displacement of the bath is treated more accurately by utilizing the exact reduced density matrix of the system. In a sense, the hybrid cumulant expansion is based on a generalized version of linear response theory with entangled initial states.

  17. Modulated Sine Waves for Differential Absorption Measurements Using a CW Laser System

    Science.gov (United States)

    Campbell, Joel F. (Inventor); Lin, Bing (Inventor); Nehrir, Amin R. (Inventor)

    2015-01-01

    A continuous wave Light Detection and Ranging (CW LiDAR) system utilizes two or more laser frequencies and time or range shifted pseudorandom noise (PN) codes to discriminate between the laser frequencies. The performance of these codes can be improved by subtracting out the bias before processing. The CW LiDAR system may be mounted to an artificial satellite orbiting the earth, and the relative strength of the return signal for each frequency can be utilized to determine the concentration of selected gases or other substances in the atmosphere.

  18. Multiple system atrophy: genetic risks and alpha-synuclein mutations [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Heather T Whittaker

    2017-11-01

    Full Text Available Multiple system atrophy (MSA is one of the few neurodegenerative disorders where we have a significant understanding of the clinical and pathological manifestations but where the aetiology remains almost completely unknown. Research to overcome this hurdle is gaining momentum through international research collaboration and a series of genetic and molecular discoveries in the last few years, which have advanced our knowledge of this rare synucleinopathy. In MSA, the discovery of α-synuclein pathology and glial cytoplasmic inclusions remain the most significant findings. Families with certain types of α-synuclein mutations develop diseases that mimic MSA, and the spectrum of clinical and pathological features in these families suggests a spectrum of severity, from late-onset Parkinson’s disease to MSA. Nonetheless, controversies persist, such as the role of common α-synuclein variants in MSA and whether this disorder shares a common mechanism of spreading pathology with other protein misfolding neurodegenerative diseases. Here, we review these issues, specifically focusing on α-synuclein mutations.

  19. Cell culture models of biological barriers: in vitro test systems for drug absorption and delivery

    National Research Council Canada - National Science Library

    Lehr, Claus-Michael

    2002-01-01

    ... may be reprinted or reproduced or utilized in any form or by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying and recording, or in any information storage or retrieval system, without permission in writing from the publishers. Every effort has been made to ensure that the advice and information in this book is t...

  20. MEMBRANOUS FLOWS IN GAS-LIQUID COLLECTORS-REGENERATORS OF SOLAR ABSORPTIVE SYSTEMS FEATURES

    Directory of Open Access Journals (Sweden)

    Doroshenko А.V.

    2009-12-01

    Full Text Available Article is devoted to the creation of new generation of solar collectors of the gas-liquid type, intended for use in alternative refrigerating and conditioning systems of drying-evaporating type with direct solar regeneration of absorbent. Special attention is given to the study of membranous flows features on inclined surfaces, including questions of such flows stability.

  1. Calibration techniques for the in vivo measurement of alpha-emitting actinides

    International Nuclear Information System (INIS)

    Fleming, R.R.

    1976-01-01

    Reliable interpretation of in vivo measurements for alpha-emitting actinides deposited in the lungs is largely dependent on three factors: correction of observed count rates for background contributions; correction for photon absorption in the body; and accurate calibration of the counting system. Terrestrial and cosmic radiation contributions can be minimized by extensive shielding and good pulse-shape discrimination. Techniques are available to minimize errors inherent in the calibration of an in vivo counting system. Minimum amounts of alpha-emitting actinides detectable in the lungs are primarily affected by the accuracy of two factors: predicted body background due to 137 Cs and 40 K, and estimated photon absorption in chest-wall tissue. A matched pair of 12.5-cm-dia phoswich detectors, purchased from the Harshaw Chemical Company, are used to measure low-energy photons emitted by the radioactive actinides

  2. Thermodynamic and economic studies of two new high efficient power-cooling cogeneration systems based on Kalina and absorption refrigeration cycles

    International Nuclear Information System (INIS)

    Rashidi, Jouan; Ifaei, Pouya; Esfahani, Iman Janghorban; Ataei, Abtin; Yoo, Chang Kyoo

    2016-01-01

    Highlights: • Proposing two new power and cooling cogeneration systems based on absorption chillers and Kalina cycles. • Model-based comparison through thermodynamic and economic standpoints. • Investigating sensitivity of system performance and costs to the key parameters. • Reducing total annual costs of the base system up to 8% by cogeneration. • Increasing thermal efficiency up to 4.9% despite of cooling generation. - Abstract: Two new power and cooling cogeneration systems based on Kalina cycle (KC) and absorption refrigeration cycle (AC) are proposed and studied from thermodynamic and economic viewpoints. The first proposed system, Kalina power-cooling cycle (KPCC), combines the refrigerant loop of the water-ammonia absorption chiller, consisting of an evaporator and two throttling valves with the KC. A portion of the KC mass flow enters the evaporator to generate cooling after being condensed in the KPCC system. KPCC is a flexible system adapting power and cooling cogeneration to the demand. The second proposed system, Kalina lithium bromide absorption chiller cycle (KLACC), consists of the KC and a single effect lithium bromide-water absorption chiller (AC_L_i_B_r_-_w_a_t_e_r). The KC subsystem discharges heat to the AC_L_i_B_r_-_w_a_t_e_r desorber before condensing in the condenser. The performance and economic aspects of both proposed systems are analyzed and compared with the stand alone KC. A parametric analysis is conducted to evaluate the sensitivity of efficiencies and the generated power and cooling quantities to the key operating variables. The results showed that, thermal efficiency and total annual costs decreased by 5.6% and 8% for KPCC system but increased 4.9% and 58% for KLACC system, respectively. Since the power-cooling efficiency of KLACC is 42% higher than KPCC it can be applied where the aim is cooling generation without considering economic aspects.

  3. Absorptive products

    International Nuclear Information System (INIS)

    Assarsson, P.G.; King, P.A.

    1976-01-01

    Applications for hydrophile gels produced by the radiation induced cross-linking in aqueous solution of polyethylene oxide and starch, as described in Norwegian patent 133501 (INIS RN 281494), such as sanitary napkins (diapers) and sanitary towels, are discussed. The process itself is also discussed and results, expressed as the percentage of insoluble gel and its absorptive capacity for saline solution as functions of the ratio of polyethylene oxide to starch and the radiation dose, are presented. (JIW)

  4. Unshifted Metastable He I* Mini-broad Absorption Line System in the Narrow-line Type 1 Quasar SDSS J080248.18+551328.9

    Science.gov (United States)

    Ji, Tuo; Zhou, Hongyan; Jiang, Peng; Wang, Tinggui; Ge, Jian; Wang, Huiyuan; Komossa, S.; Hamann, Fred; Zuther, Jens; Liu, Wenjuan; Lu, Honglin; Zuo, Wenwen; Yang, Chenwei; Yuan, Weimin

    2015-02-01

    We report the identification of an unusual absorption-line system in the quasar SDSS J080248.18+551328.9 and present a detailed study of the system, incorporating follow-up optical and near-IR spectroscopy. A few tens of absorption lines are detected, including He I*, Fe II*, and Ni II*, which arise from metastable or excited levels, as well as resonant lines in Mg I, Mg II, Fe II, Mn II, and Ca II. All of the isolated absorption lines show the same profile of width Δv ~ 1500 km s-1 centered at a common redshift as that of the quasar emission lines, such as [O II], [S II], and hydrogen Paschen and Balmer series. With narrow Balmer lines, strong optical Fe II multiplets, and weak [O III] doublets, its emission-line spectrum is typical for that of a narrow-line Seyfert 1 galaxy (NLS1). We have derived reliable measurements of the gas-phase column densities of the absorbing ions/levels. Photoionization modeling indicates that the absorber has a density of n H ~ (1.0-2.5) × 105 cm-3 and a column density of N H ~ (1.0-3.2) × 1021 cm-2 and is located at R ~100-250 pc from the central supermassive black hole. The location of the absorber, the symmetric profile of the absorption lines, and the coincidence of the absorption- and emission-line centroid jointly suggest that the absorption gas originates from the host galaxy and is plausibly accelerated by stellar processes, such as stellar winds and/or supernova explosions. The implications for the detection of such a peculiar absorption-line system in an NLS1 are discussed in the context of coevolution between supermassive black hole growth and host galaxy buildup.

  5. An antiaging skin care system containing alpha hydroxy acids and vitamins improves the biomechanical parameters of facial skin

    Science.gov (United States)

    Tran, Diana; Townley, Joshua P; Barnes, Tanya M; Greive, Kerryn A

    2015-01-01

    Background The demand for antiaging products has dramatically increased in recent years, driven by an aging population seeking to maintain the appearance of youth. This study investigates the effects of an antiaging skin care system containing alpha hydroxy acids (AHAs) in conjunction with vitamins B3, C, and E on the biomechanical parameters of facial skin. Methods Fifty two volunteers followed an antiaging skin care regimen comprising of cleanser, eye cream, day moisturizer, and night moisturizer for 21 days. Wrinkle depth (Ry) and skin roughness (Ra) were measured by skin surface profilometry of the crow’s feet area, and skin elasticity parameters R2 (gross elasticity), R5 (net elasticity), R6 (viscoelastic portion), and R7 (recovery after deformation) were determined for facial skin by cutometer, preapplication and after 7, 14, and 21 days. Volunteers also completed a self-assessment questionnaire. Results Compared to baseline, Ry and Ra significantly improved by 32.5% (P<0.0001) and 42.9% (P<0.0001), respectively, after 21 days of antiaging skin care treatment. These results were observed by the volunteers with 9 out of 10 discerning an improvement in skin texture and smoothness. Compared to baseline, R2 and R5 significantly increased by 15.2% (P<0.0001) and 12.5% (P=0.0449), respectively, while R6 significantly decreased by 17.7% (P<0.0001) after 21 days. R7 increased by 9.7% after 21 days compared to baseline but this was not significant over this time period. Conclusion An antiaging skin care system containing AHAs and vitamins significantly improves the biomechanical parameters of the skin including wrinkles and skin texture, as well as elasticity without significant adverse effects. PMID:25552908

  6. Development of a preclinical 211Rn/211At generator system for targeted alpha therapy research with 211At.

    Science.gov (United States)

    Crawford, Jason R; Yang, Hua; Kunz, Peter; Wilbur, D Scott; Schaffer, Paul; Ruth, Thomas J

    2017-05-01

    The availability of 211 At for targeted alpha therapy research can be increased by the 211 Rn/ 211 At generator system, whereby 211 At is produced by 211 Rn electron capture decay. This study demonstrated the feasibility of using generator-produced 211 At to label monoclonal antibody (BC8, anti-human CD45) for preclinical use, following isolation from the 207 Po contamination also produced by these generators (by 211 Rn α-decay). 211 Rn was produced by 211 Fr electron capture decay following mass separated ion beam implantation and chemically isolated in liquid alkane hydrocarbon (dodecane). 211 At produced by the resulting 211 Rn source was extracted in strong base (2N NaOH) and purified by granular Te columns. BC8-B10 (antibody conjugated with closo-decaborate(2-)) was labeled with generator-produced 211 At and purified by PD-10 columns. Aqueous solutions extracted from the generator were found to contain 211 At and 207 Po, isolated from 211 Rn. High radionuclidic purity was obtained for 211 At eluted from Te columns, from which BC8-B10 monoclonal antibody was successfully labeled. If not removed, 207 Po was found to significantly contaminate the final 211 At-BC8-B10 product. High yield efficiencies (decay-corrected, n=3) were achieved for 211 At extraction from the generator (86%±7%), Te column purification (70%±10%), and antibody labeling (76%±2%). The experimental 211 Rn/ 211 At generator was shown to be well-suited for preclinical 211 At-based research. We believe that these experiments have furthered the knowledge-base for expanding accessibility to 211 At using the 211 Rn/ 211 At generator system. As established by this work, the 211 Rn/ 211 At generator has the capability of facilitating preclinical evaluations of 211 At-based therapies. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Changes in autonomic nervous system activity after treatment with alpha-blocker in men with lower urinary tract symptoms

    Directory of Open Access Journals (Sweden)

    Kang Hee Shim

    2018-01-01

    Full Text Available Purpose: To determine changes in autonomic nervous system activity after treatment in men with lower urinary tract symptoms (LUTS, we evaluated changes in patients' symptoms, uroflowmetry, and heart rate variability (HRV after treatment with alpha-blockers for 12 weeks. Materials and Methods: Ninety-five men who had LUTS (International Prostate Symptom Score [IPSS] ≥8 were included in this study. We divided them into two groups on the basis of a low frequency/high frequency (LF/HF ratio of 1.6. After treatment with Xatral XL (Handok Inc., Korea 10 mg for 3 months, we rechecked their IPSS, uroflowmetry, HRV and compared these with the baseline measurements. Results: Fifty-four men were assigned to the low LF/HF group (group A: LF/HF ≤1.6 and 41 men to the high LF/HF group (group B: LF/HF >1.6. At baseline and 12 weeks, none of the parameters differed significantly between the groups except for HF, which is one of the parameters of HRV. IPSS, the IPSS-voiding subscore, and the IPSS-storage subscore decreased and maximal uroflow increased significantly after 12 weeks of treatment. Whereas the baseline LF/HF ratio increased from 0.89±0.407 to 1.80±1.804 after treatment in group A, it decreased from 3.93±5.471 to 1.79±1.153 in group B. Conclusions: The efficacies of Xatral XL were clear in both groups. We found that the LF/HF ratio in the two groups merged to a value of approximately 1.79 after treatment. We suggest that this could be a clue to the importance of balance in autonomic nervous system activity in men with LUTS.

  8. Molecular dynamics simulation of a nanofluidic energy absorption system: effects of the chiral vector of carbon nanotubes.

    Science.gov (United States)

    Ganjiani, Sayed Hossein; Hossein Nezhad, Alireza

    2018-02-14

    A Nanofluidic Energy Absorption System (NEAS) is a novel nanofluidic system with a small volume and weight. In this system, the input mechanical energy is converted to surface tension energy during liquid infiltration in the nanotube. The NEAS is made of a mixture of nanoporous material particles in a functional liquid. In this work, the effects of the chiral vector of a carbon nanotube (CNT) on the performance characteristics of the NEAS are investigated by using molecular dynamics simulation. For this purpose, six CNTs with different diameters for each type of armchair, zigzag and chiral, and several chiral CNTs with different chiral vectors (different values of indices (m,n)) are selected and studied. The results show that in the chiral CNTs, the contact angle shows the hydrophobicity of the CNT, and infiltration pressure is reduced by increasing the values of m and n (increasing the CNT diameter). Contact angle and infiltration pressure are decreased by almost 1.4% and 9% at all diameters, as the type of CNT is changed from chiral to zigzag and then to armchair. Absorbed energy density and efficiency are also decreased by increasing m and n and by changing the type of CNT from chiral to zigzag and then to armchair.

  9. Modeling of intensity-modulated continuous-wave laser absorption spectrometer systems for atmospheric CO(2) column measurements.

    Science.gov (United States)

    Lin, Bing; Ismail, Syed; Wallace Harrison, F; Browell, Edward V; Nehrir, Amin R; Dobler, Jeremy; Moore, Berrien; Refaat, Tamer; Kooi, Susan A

    2013-10-10

    The focus of this study is to model and validate the performance of intensity-modulated continuous-wave (IM-CW) CO(2) laser absorption spectrometer (LAS) systems and their CO(2) column measurements from airborne and satellite platforms. The model accounts for all fundamental physics of the instruments and their related CO(2) measurement environments, and the modeling results are presented statistically from simulation ensembles that include noise sources and uncertainties related to the LAS instruments and the measurement environments. The characteristics of simulated LAS systems are based on existing technologies and their implementation in existing systems. The modeled instruments are specifically assumed to be IM-CW LAS systems such as the Exelis' airborne multifunctional fiber laser lidar (MFLL) operating in the 1.57 μm CO(2) absorption band. Atmospheric effects due to variations in CO(2), solar radiation, and thin clouds, are also included in the model. Model results are shown to agree well with LAS atmospheric CO(2) measurement performance. For example, the relative bias errors of both MFLL simulated and measured CO(2) differential optical depths were found to agree to within a few tenths of a percent when compared to the in situ observations from the flight of 3 August 2011 over Railroad Valley (RRV), Nevada, during the summer 2011 flight campaign. In addition, the horizontal variations in the model CO(2) differential optical depths were also found to be consistent with those from MFLL measurements. In general, the modeled and measured signal-to-noise ratios (SNRs) of the CO(2) column differential optical depths (τd) agreed to within about 30%. Model simulations of a spaceborne IM-CW LAS system in a 390 km dawn/dusk orbit for CO(2) column measurements showed that with a total of 42 W of transmitted power for one offline and two different sideline channels (placed at different locations on the side of the CO(2) absorption line), the accuracy of the

  10. Social absorption capability, systems of innovation and manufactured export response to preferential trade incentives

    DEFF Research Database (Denmark)

    Na-Allah, Abdelrasaq; Muchie, Mammo

    2012-01-01

    In many extant analyses of non-reciprocal system of trade preferences, it is typical to focus on the details of market access value of tarrif concessions as explanation for why export beneficiaries may or may not respond to include very often the role that supply related factors can, and do play...... & Opportunity Act apparel trade incentive is used as a classical illustration of this proposition. It is shown that the comparative efficiency of Lesetho, despite emerging from a relatively weak trade performance potential background, in recording the highest level of export success among beneficiaries...

  11. Effect of Moisture Exchange on Interface Formation in the Repair System Studied by X-ray Absorption

    Directory of Open Access Journals (Sweden)

    Mladena Lukovic

    2015-12-01

    Full Text Available In concrete repair systems, material properties of the repair material and the interface are greatly influenced by the moisture exchange between the repair material and the substrate. If the substrate is dry, it can absorb water from the repair material and reduce its effective water-to-cement ratio (w/c. This further affects the hydration rate of cement based material. In addition to the change in hydration rate, void content at the interface between the two materials is also affected. In this research, the influence of moisture exchange on the void content in the repair system as a function of initial saturation level of the substrate is investigated. Repair systems with varying level of substrate saturation are made. Moisture exchange in these repair systems as a function of time is monitored by the X-ray absorption technique. After a specified curing age (3 d, the internal microstructure of the repair systems was captured by micro-computed X-ray tomography (CT-scanning. From reconstructed images, different phases in the repair system (repair material, substrate, voids can be distinguished. In order to quantify the void content, voids were thresholded and their percentage was calculated. It was found that significantly more voids form when the substrate is dry prior to application of the repair material. Air, initially filling voids and pores of the dry substrate, is being released due to the moisture exchange. As a result, air voids remain entrapped in the repair material close to the interface. These voids are found to form as a continuation of pre-existing surface voids in the substrate. Knowledge about moisture exchange and its effects provides engineers with the basis for recommendations about substrate preconditioning in practice.

  12. Effect of Moisture Exchange on Interface Formation in the Repair System Studied by X-ray Absorption.

    Science.gov (United States)

    Lukovic, Mladena; Ye, Guang

    2015-12-22

    In concrete repair systems, material properties of the repair material and the interface are greatly influenced by the moisture exchange between the repair material and the substrate. If the substrate is dry, it can absorb water from the repair material and reduce its effective water-to-cement ratio (w/c). This further affects the hydration rate of cement based material. In addition to the change in hydration rate, void content at the interface between the two materials is also affected. In this research, the influence of moisture exchange on the void content in the repair system as a function of initial saturation level of the substrate is investigated. Repair systems with varying level of substrate saturation are made. Moisture exchange in these repair systems as a function of time is monitored by the X-ray absorption technique. After a specified curing age (3 d), the internal microstructure of the repair systems was captured by micro-computed X-ray tomography (CT-scanning). From reconstructed images, different phases in the repair system (repair material, substrate, voids) can be distinguished. In order to quantify the void content, voids were thresholded and their percentage was calculated. It was found that significantly more voids form when the substrate is dry prior to application of the repair material. Air, initially filling voids and pores of the dry substrate, is being released due to the moisture exchange. As a result, air voids remain entrapped in the repair material close to the interface. These voids are found to form as a continuation of pre-existing surface voids in the substrate. Knowledge about moisture exchange and its effects provides engineers with the basis for recommendations about substrate preconditioning in practice.

  13. Benchmarking the Geant4 full system simulation of an associated alpha-particle detector for use in a D-T neutron generator.

    Science.gov (United States)

    Zhang, Xiaodong; Hayward, Jason P; Cates, Joshua W; Hausladen, Paul A; Laubach, Mitchell A; Sparger, Johnathan E; Donnald, Samuel B

    2012-08-01

    The position-sensitive alpha-particle detector used to provide the starting time and initial direction of D-T neutrons in a fast-neutron imaging system was simulated with a Geant4-based Monte Carlo program. The whole detector system, which consists of a YAP:Ce scintillator, a fiber-optic faceplate, a light guide, and a position-sensitive photo-multiplier tube (PSPMT), was modeled, starting with incident D-T alphas. The scintillation photons, whose starting time follows the distribution of a scintillation decay curve, were produced and emitted uniformly into a solid angle of 4π along the track segments of the alpha and its secondaries. Through tracking all photons and taking into account the quantum efficiency of the photocathode, the number of photoelectrons and their time and position distributions were obtained. Using a four-corner data reconstruction formula, the flood images of the alpha detector with and without optical grease between the YAP scintillator and the fiber-optic faceplate were obtained, which show agreement with the experimental results. The reconstructed position uncertainties of incident alpha particles for both cases are 1.198 mm and 0.998 mm respectively across the sensitive area of the detector. Simulation results also show that comparing with other faceplates composed of 500 μm, 300 μm, and 100 μm fibers, the 10-μm-fiber faceplate is the best choice to build the detector for better position performance. In addition, the study of the background originating inside the D-T generator suggests that for 500-μm-thick YAP:Ce coated with 1-μm-thick aluminum, and very good signal-to-noise ratio can be expected through application of a simple threshold. Copyright © 2012 Elsevier Ltd. All rights reserved.

  14. Load Absorption Characteristics of Tyre Production Waste Rubber for Playground Floor Systems

    Directory of Open Access Journals (Sweden)

    Abdul Ghani A.N.

    2014-01-01

    Full Text Available The floor surfaces where slides and swings are placed in parks and playrooms should be soft and thick to ensure that whenever a child falls, the surface can withstand the impact and minimize injuries to the child. Shredded tyres from waste tyres or waste rubber from tyre manufacturing could become beneficial as shock absorber material which can be used as a playground floor. In this study, rubber cubes and rubber pads with 5%, 8% and 10% SBR mixes were prepared for mechanical testing. Two types of floor design surfaces with and without plywood on the surface were assembled for the shock test. Gmax and HIC of this waste rubber flooring system were investigated using the compression test for the rubber cube and the drop test for the rubber pad. The criteria of general protection standards are 200g for optimum acceleration and 1000 for HIC. The Gmax and HIC results indicated that the material and system could ensure a safe fall from up to 1.0m height.

  15. Mathematical modelling of heat absorption capacity of containment spray system in a 700 MWe PHWR

    International Nuclear Information System (INIS)

    Kota, Sampath Bharadwaj; Ali, Seik Mansoor; Balasubramaniyan, V.

    2015-01-01

    This paper presents a mathematical model for estimating the heat removal by containment spray system in the post Loss of Coolant Accident (LOCA) environment. The procedure involves firstly, the calculation of heat removal rates by droplets of spray dispersed in the air-steam mixture by an appropriate direct contact condensation model accounting for the presence of non-condensable gas (air). Parametric influence of droplet size, ambient pressure and temperature on heat flux is brought out. It was found that the heat flux is inversely proportional to the ambient pressure and diameter. A spray module was subsequently developed and incorporated into an in-house containment thermal hydraulics code. The pressure and temperature transients in a 700 MWe PHWR containment building following a Large Break LOCA was obtained using this code. The efficacy of the spray in condensing the steam is shown by comparing the transients with and without the operation of spray system. Parametric studies are also conducted with respect to droplet size and flow rate of water droplet spray. The details of the investigation are presented and discussed in this paper. (author)

  16. Interaction between alpha 2-adrenergic and angiotensin II systems in the control of glomerular hemodynamics as assessed by renal micropuncture in the rat

    Science.gov (United States)

    Thomson, S. C.; Gabbai, F. B.; Tucker, B. J.; Blantz, R. C.

    1992-01-01

    The hypothesis that renal alpha 2 adrenoceptors influence nephron filtration rate (SNGFR) via interaction with angiotensin II (AII) was tested by renal micropuncture. The physical determinants of SNGFR were assessed in adult male Munich Wistar rats 5-7 d after ipsilateral surgical renal denervation (DNX). DNX was performed to isolate inhibitory central and presynaptic alpha 2 adrenoceptors from end-organ receptors within the kidney. Two experimental protocols were employed: one to test whether prior AII receptor blockade with saralasin would alter the glomerular hemodynamic response to alpha 2 adrenoceptor stimulation with the selective agonist B-HT 933 under euvolemic conditions, and the other to test whether B-HT 933 would alter the response to exogenous AII under conditions of plasma volume expansion. In euvolemic rats, B-HT 933 caused SNGFR to decline as the result of a decrease in glomerular ultrafiltration coefficient (LpA), an effect that was blocked by saralasin. After plasma volume expansion, B-HT 933 showed no primary effect on LpA but heightened the response of arterial blood pressure, glomerular transcapillary pressure gradient, and LpA to AII. The parallel results of these converse experiments suggest a complementary interaction between renal alpha 2-adrenergic and AII systems in the control of LpA.

  17. The help of simulation codes in designing waste assay systems using neutron measurement methods: Application to the alpha low level waste assay system PROMETHEE 6

    Energy Technology Data Exchange (ETDEWEB)

    Mariani, A.; Passard, C.; Jallu, F. E-mail: fanny.jallu@cea.fr; Toubon, H

    2003-11-01

    The design of a specific nuclear assay system for a dedicated application begins with a phase of development, which relies on information from the literature or on knowledge resulting from experience, and on specific experimental verifications. The latter ones may require experimental devices which can be restricting in terms of deadline, cost and safety. One way generally chosen to bypass these difficulties is to use simulation codes to study particular aspects. This paper deals with the potentialities offered by the simulation in the case of a passive-active neutron (PAN) assay system for alpha low level waste characterization; this system has been carried out at the Nuclear Measurements Development Laboratory of the French Atomic Energy Commission. Due to the high number of parameters to be taken into account for its development, this is a particularly sophisticated example. Since the PAN assay system, called PROMETHEE (prompt epithermal and thermal interrogation experiment), must have a detection efficiency of more than 20% and preserve a high level of modularity for various applications, an improved version has been studied using the MCNP4 (Monte Carlo N-Particle) transport code. Parameters such as the dimensions of the assay system, of the cavity and of the detection blocks, and the thicknesses of the nuclear materials of neutronic interest have been optimised. Therefore, the number of necessary experiments was reduced.

  18. The help of simulation codes in designing waste assay systems using neutron measurement methods: Application to the alpha low level waste assay system PROMETHEE 6

    International Nuclear Information System (INIS)

    Mariani, A.; Passard, C.; Jallu, F.; Toubon, H.

    2003-01-01

    The design of a specific nuclear assay system for a dedicated application begins with a phase of development, which relies on information from the literature or on knowledge resulting from experience, and on specific experimental verifications. The latter ones may require experimental devices which can be restricting in terms of deadline, cost and safety. One way generally chosen to bypass these difficulties is to use simulation codes to study particular aspects. This paper deals with the potentialities offered by the simulation in the case of a passive-active neutron (PAN) assay system for alpha low level waste characterization; this system has been carried out at the Nuclear Measurements Development Laboratory of the French Atomic Energy Commission. Due to the high number of parameters to be taken into account for its development, this is a particularly sophisticated example. Since the PAN assay system, called PROMETHEE (prompt epithermal and thermal interrogation experiment), must have a detection efficiency of more than 20% and preserve a high level of modularity for various applications, an improved version has been studied using the MCNP4 (Monte Carlo N-Particle) transport code. Parameters such as the dimensions of the assay system, of the cavity and of the detection blocks, and the thicknesses of the nuclear materials of neutronic interest have been optimised. Therefore, the number of necessary experiments was reduced

  19. Atomic absorption instrument functional description

    International Nuclear Information System (INIS)

    Bystroff, R.I.; Boyle, W.G. Jr.; Barton, G.W. Jr.

    1976-01-01

    This report describes a proposed system for automating atomic absorption analysis. The system consists of two atomic absorption instruments and an automatic sampler that can be attached to either instrument. A computer program controls the sampling and gathers data. The program then uses the data to perform bookkeeping, data processing, and report writing

  20. Recent Advances in Delivery Systems and Therapeutics of Cinnarizine: A Poorly Water Soluble Drug with Absorption Window in Stomach

    Directory of Open Access Journals (Sweden)

    Smita Raghuvanshi

    2014-01-01

    Full Text Available Low solubility causing low dissolution in gastrointestinal tract is the major problem for drugs meant for systemic action after oral administration, like cinnarizine. Pharmaceutical products of cinnarizine are commercialized globally as immediate release preparations presenting low absorption with low and erratic bioavailability. Approaches to enhance bioavailability are widely cited in the literature. An attempt has been made to review the bioavailability complications and clinical therapeutics of poorly water soluble drug: cinnarizine. The interest of writing this paper is to summarize the pharmacokinetic limitations of drug with special focus on strategies to improvise bioavailability along with effectiveness of novel dosage forms to circumvent the obstacle. The paper provides insight to the approaches to overcome low and erratic bioavailability of cinnarizine by cyclodextrin complexes and novel dosage forms: self-nanoemulsifying systems and buoyant microparticulates. Nanoformulations need to systematically explored in future, for their new clinical role in prophylaxis of migraine attacks in children. Clinical reports have affirmed the role of cinnarizine in migraine prophylaxis. Research needs to be dedicated to develop dosage forms for efficacious bioavailability and drug directly to brain.

  1. Modeling and experimental validation of the solar loop for absorption solar cooling system using double-glazed collectors

    International Nuclear Information System (INIS)

    Marc, Olivier; Praene, Jean-Philippe; Bastide, Alain; Lucas, Franck

    2011-01-01

    Solar cooling applied to buildings is without a doubt an interesting alternative for reducing energy consumption in traditional mechanical steam compression air conditioning systems. The study of these systems should have a closely purely fundamental approach including the development of numerical models in order to predict the overall installation performance. The final objective is to estimate cooling capacity, power consumption, and overall installation performance with relation to outside factors (solar irradiation, outside temperature...). The first stage in this work consists of estimating the primary energy produced by the solar collector field. The estimation of this primary energy is crucial to ensure the evaluation of the cooling capacity and therefore the cooling distribution and thermal comfort in the building. Indeed, the absorption chiller performance is directly related to its heat source. This study presents dynamic models for double glazing solar collectors and compares the results of the simulation with experimental results taken from our test bench (two collectors). In the second part, we present an extensive collector field model (36 collectors) from our solar cooling installation at The University Institute of Technology in St Pierre, Reunion Island as well as our stratified tank storage model. A comparison of the simulation results with real scale solar experimental data taken from our installation enables validation of the double glazing solar collector and stratified tank dynamic models.

  2. Sulfur K-edge absorption spectroscopy on selected biological systems; Schwefel-K-Kanten-Absorptionsspektroskopie an ausgewaehlten biologischen Systemen

    Energy Technology Data Exchange (ETDEWEB)

    Lichtenberg, Henning

    2008-07-15

    Sulfur is an essential element in organisms. In this thesis investigations of sulfur compounds in selected biological systems by XANES (X-ray Absorption Near Edge Structure) spectroscopy are reported. XANES spectroscopy at the sulfur K-edge provides an excellent tool to gain information about the local environments of sulfur atoms in intact biological samples - no extraction processes are required. Spatially resolved measurements using a Kirkpatrick-Baez mirror focusing system were carried out to investigate the infection of wheat leaves by rust fungi. The results give information about changes in the sulfur metabolism of the host induced by the parasite and about the extension of the infection into visibly uninfected plant tissue. Furthermore, XANES spectra of microbial mats from sulfidic caves were measured. These mats are dominated by microbial groups involved in cycling sulfur. Additionally, the influence of sulfate deprivation and H{sub 2}S exposure on sulfur compounds in onion was investigated. To gain an insight into the thermal degradation of organic material the influence of roasting of sulfur compounds in coffee beans was studied. (orig.)

  3. Comparative studies of H absorption/desorption kinetics and evaporation of liquid lithium in different porous systems and free surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Oyarzabal, E., E-mail: eider.oyarzabal@externos.ciemat.es [Ass. Euratom-Ciemat, Av. Complutense 22, 28040 Madrid (Spain); Calle de Guzmán el Bueno, 133, 28003 Madrid (Spain); Martín-Rojo, A.B. [Ass. Euratom-Ciemat, Av. Complutense 22, 28040 Madrid (Spain); Calle de Guzmán el Bueno, 133, 28003 Madrid (Spain); Tabarés, F.L. [Ass. Euratom-Ciemat, Av. Complutense 22, 28040 Madrid (Spain)

    2017-04-15

    In the present work, a study of the two most relevant properties of liquid lithium with respect to its suitability as a Plasma Facing Component (PFC) element in a Reactor, namely, its evaporation rate and the uptake/release of hydrogen, eventually leading to the formation of a stable hydride was carried out for Li in different porous systems and Li as a free surface. These properties were characterized in a temperature range of 200–500 °C. The H{sub 2} absorption kinetics at low pressure (<1torr) were measured for the different studied porous systems and then outgassed. Particle balance and chemical analysis were used to assess the retention properties of lithium for each case. Thermal Desorption Spectroscopy (TDS) analysis was used for the assessment of possible hydride formation. Evaporation rates were determined by using a Quartz Microbalance (QMB). A significant reduction of the evaporation rate was observed when Li was trapped in a microstructure of sintered stainless steel with a characteristic porous size of 5–10 μm. On the other hand, a negligible rate of H{sub 2} uptake was found at temperatures above 500 °C in all cases.

  4. Aqueous suspensions of {alpha}Al{sub 2}O{sub 3}/SiC mixed systems

    Energy Technology Data Exchange (ETDEWEB)

    Pagnoux, C.; Baklouti, S.; Chartier, T.; Baumard, J.F. [ENSCI, Limoges (France). LMCTS

    1997-12-31

    The preparation of aqueous {alpha}-Al{sub 2}O{sub 3}, {alpha}-SiO{sub 2} and {alpha}-SiC suspensions with polyelectrolytes, respectively the NH{sub 4}{sup +} salt of polymethacrylic acid (PMA-NH{sub 4}{sup +}) and acidic form polyethylene imine (PEI-H{sup +}) is investigated. It is based on the adsorption of these polyelectrolytes which in turn depends mainly on the nature of the polyelectrolyte, and the charge density which develops on the powder surface in water. Good dispersion and stability of dispersions are then obtained through electrostatic and steric stabilization. As an application, the preparation of an Al{sub 2}O{sub 3}-SiC aqueous mixed slurry was investigated as a preliminary step for processing of Al{sub 2}O{sub 3}/SiC nanocomposites. (orig.) 2 refs.

  5. Effects of local alpha2-adrenergic receptor blockade on adipose tissue lipolysis during prolonged systemic adrenaline infusion in normal man

    DEFF Research Database (Denmark)

    Simonsen, Lene; Enevoldsen, Lotte H; Stallknecht, Bente

    2008-01-01

    During prolonged adrenaline infusion, lipolysis peaks within 30 min and thereafter tends to decline, and we hypothesized that the stimulation of local adipose tissue alpha2-adrenergic receptors accounts for this decline. The lipolytic effect of a prolonged intravenous adrenaline infusion combined....... Regional adipose tissue blood flow was measured by the (133)Xe clearance technique. Regional glycerol output (lipolytic rate) was calculated from these measurements and simultaneous measurements of arterial glycerol concentrations. Adrenaline infusion increased lipolysis in all three depots (data...... circulating adrenaline concentrations, and the decrease in lipolysis in subcutaneous adipose tissue under prolonged adrenaline stimulation is thus not attributed to alpha2-adrenergic receptor inhibition of lipolysis. However, in the preperitoneal adipose tissue depot, alpha2-adrenergic receptor tone plays...

  6. Intratumoral IL-12 and TNF-alpha-loaded microspheres lead to regression of breast cancer and systemic antitumor immunity.

    Science.gov (United States)

    Sabel, Michael S; Skitzki, Joseph; Stoolman, Lloyd; Egilmez, Nejat K; Mathiowitz, Edith; Bailey, Nicola; Chang, Wen-Jian; Chang, Alfred E

    2004-02-01

    Local, sustained delivery of cytokines at a tumor can enhance induction of antitumor immunity and may be a feasible neoadjuvant immunotherapy for breast cancer. We evaluated the ability of intratumoral poly-lactic-acid-encapsulated microspheres (PLAM) containing interleukin 12 (IL-12), tumor necrosis factor alpha (TNF-alpha), and granulocyte-macrophage colony stimulating factor (GM-CSF) in a murine model of breast cancer to generate a specific antitumor response. BALB/c mice with established MT-901 tumors underwent resection or treatment with a single intratumoral injection of PLAM containing IL-12, TNF-alpha, or GM-CSF, alone or in combination. Two weeks later, lymph nodes and spleens were harvested, activated with anti-CD3 monoclonal antibodies (mAb) and rhIL-2, and assessed for antitumor reactivity by an interferon gamma (IFNgamma) release assay. Tumor-infiltrating lymphocyte (TIL) analysis was performed on days 2 and 5 after treatment by mechanically processing the tumors to create a single cell suspension, followed by three-color fluorescence-activated cell sorter (FACS) analysis. Intratumoral injection of cytokine-loaded PLAM significantly suppressed tumor growth, with the combination of IL-12 and TNF-alpha leading to increased infiltration by polymorphonuclear cells and CD8+ T-cells in comparison with controls. The induction of tumor-specific reactive T-cells in the nodes and spleens, as measured by IFN-gamma production, was highest with IL-12 and TNF-alpha. This treatment resulted in resistance to tumor rechallenge. A single intratumoral injection of IL-12 and TNF-alpha-loaded PLAM into a breast tumor leads to infiltration by polymorphonuclear cells and CD8+ T-cells with subsequent tumor regression. In addition, this local therapy induces specific antitumor T-cells in the lymph nodes and spleens, resulting in memory immune response.

  7. Rossi Alpha Method

    International Nuclear Information System (INIS)

    Hansen, G.E.

    1985-01-01

    The Rossi Alpha Method has proved to be valuable for the determination of prompt neutron lifetimes in fissile assemblies having known reproduction numbers at or near delayed critical. This workshop report emphasizes the pioneering applications of the method by Dr. John D. Orndoff to fast-neutron critical assemblies at Los Alamos. The value of the method appears to disappear for subcritical systems where the Rossi-α is no longer an α-eigenvalue

  8. Waste reduction efforts through the evaluation and procurement of a digital camera system for the Alpha-Gamma Hot Cell Facility at Argonne National Laboratory-East

    International Nuclear Information System (INIS)

    Bray, T. S.; Cohen, A. B.; Tsai, H.; Kettman, W. C.; Trychta, K.

    1999-01-01

    The Alpha-Gamma Hot Cell Facility (AGHCF) at Argonne National Laboratory-East is a research facility where sample examinations involve traditional photography. The AGHCF documents samples with photographs (both Polaroid self-developing and negative film). Wastes generated include developing chemicals. The AGHCF evaluated, procured, and installed a digital camera system for the Leitz metallograph to significantly reduce labor, supplies, and wastes associated with traditional photography with a return on investment of less than two years

  9. Absorption of carbon dioxide and isotope exchange rate of carbon in a reaction system between carbon dioxide and carbamic acid

    International Nuclear Information System (INIS)

    Takeshita, Kenji; Kitamoto, Asashi

    1985-01-01

    The performance of isotope separation of carbon-13 by chemical exchange between carbon dioxide and carbamic acid was studied. The working fluid used in the study was a solution of DNBA, (C 4 H 9 ) 2 NH and n-octane mixture. Factors related to the isotope exchange rate were measured, such as the absorption rate of carbon dioxide into the solution of DNBA and n-octane, the isotope exchange rate and the separation factor in the reaction between CO 2 and carbamic acid. The absorption of CO 2 into the working fluid was the sum of chemical absorption by DNBA and physical absorption by n-octane. The absorption of carbon dioxide into the working fluid was negligible at temperatures over 90 0 C, but increased gradually at lower temperatures. Carbon dioxide was absorbed into DNBA by chemical absorption, and DNBA was converted to carbamic acid by the reaction. The reaction for synthesis and decomposition of carbamic acid was reversible. The separation factor in equilibrium reached a large value at lower temperatures. The isotope exchange rate between gas and liquid was proportional to the product of the concentration of carbamic acid and the concentration of CO 2 by physical absorption. The isotope separation of carbon by chemical exchange reaction is better operated under the conditions of lower temperature and higher pressure. (author)

  10. H2S absorption and desorption system for a heavy water production plant (Gird ler-Sulphide method)

    International Nuclear Information System (INIS)

    Diaz, F.; Duran, O.

    1987-01-01

    A computational design for the principal equipment involved in the absorption and desorption sections of a heavy water production plant (Girdler-sulphide method) is described. the programs were developed in FORTRAN. A detailled description of transport equations for the desorption tower, which are applicable for the absorption one is included. The optimization criteria used for the equipment design were mainly economic; the results were obtained under the optimal conditions for the towers. The programs may be used in the long term, for the simulation of the absorption and desorption sections together with the isotopic exchange sectionts (author)

  11. Wide-area remote-sensing system of pollution and gas dispersal by near-infrared absorption based on low-loss optical fiber network

    Science.gov (United States)

    Inaba, H.

    1986-01-01

    An all optical remote sensing system utilizing long distance, ultralow loss optical fiber networks is studied and discussed for near infrared absorption measurements of combustible and/or explosive gases such as CH4 and C3H8 in our environment, including experimental results achieved in a diameter more than 20 km. The use of a near infrared wavelength range is emphasized.

  12. Lyman alpha SMM/UVSP absolute calibration and geocoronal correction

    Science.gov (United States)

    Fontenla, Juan M.; Reichmann, Edwin J.

    1987-01-01

    Lyman alpha observations from the Ultraviolet Spectrometer Polarimeter (UVSP) instrument of the Solar Maximum Mission (SMM) spacecraft were analyzed and provide instrumental calibration details. Specific values of the instrument quantum efficiency, Lyman alpha absolute intensity, and correction for geocoronal absorption are presented.

  13. Extrapolation of systemic bioavailability assessing skin absorption and epidermal and hepatic metabolism of aromatic amine hair dyes in vitro.

    Science.gov (United States)

    Manwaring, John; Rothe, Helga; Obringer, Cindy; Foltz, David J; Baker, Timothy R; Troutman, John A; Hewitt, Nicola J; Goebel, Carsten

    2015-09-01

    Approaches to assess the role of absorption, metabolism and excretion of cosmetic ingredients that are based on the integration of different in vitro data are important for their safety assessment, specifically as it offers an opportunity to refine that safety assessment. In order to estimate systemic exposure (AUC) to aromatic amine hair dyes following typical product application conditions, skin penetration and epidermal and systemic metabolic conversion of the parent compound was assessed in human skin explants and human keratinocyte (HaCaT) and hepatocyte cultures. To estimate the amount of the aromatic amine that can reach the general circulation unchanged after passage through the skin the following toxicokinetically relevant parameters were applied: a) Michaelis-Menten kinetics to quantify the epidermal metabolism; b) the estimated keratinocyte cell abundance in the viable epidermis; c) the skin penetration rate; d) the calculated Mean Residence Time in the viable epidermis; e) the viable epidermis thickness and f) the skin permeability coefficient. In a next step, in vitro hepatocyte Km and Vmax values and whole liver mass and cell abundance were used to calculate the scaled intrinsic clearance, which was combined with liver blood flow and fraction of compound unbound in the blood to give hepatic clearance. The systemic exposure in the general circulation (AUC) was extrapolated using internal dose and hepatic clearance, and Cmax was extrapolated (conservative overestimation) using internal dose and volume of distribution, indicating that appropriate toxicokinetic information can be generated based solely on in vitro data. For the hair dye, p-phenylenediamine, these data were found to be in the same order of magnitude as those published for human volunteers. Copyright © 2015. Published by Elsevier Inc.

  14. The dust, nebular emission, and dependence on QSO radio properties of the associated Mg II absorption line systems

    International Nuclear Information System (INIS)

    Khare, Pushpa; Daniel, Vanden Berk; Rahmani, Hadi; York, Donald G.

    2014-01-01

    We studied dust reddening and [O II] emission in 1730 Mg II associated absorption systems (AAS; relative velocity with respect to QSOs, ≤3000 km s –1 ; in units of velocity of light, β, ≤0.01) with 0.4 ≤z abs ≤ 2 in the Sloan Digital Sky Survey DR7, focusing on their dependence on the radio and other QSO properties. We used control samples, several with matching radio properties, to show that (1) AAS in radio-detected (RD) QSOs cause 2.6 ± 0.2 times higher dust extinction than those in radio-undetected (RUD) ones, which in turn cause 2.9 ± 0.7 times the dust extinction in the intervening systems; (2) AAS in core-dominated QSOs cause 2.0 ± 0.1 times higher dust extinction than those in lobe-dominated QSOs; (3) the occurrence of AAS is 2.1 ± 0.2 times more likely in RD QSOs than in RUD QSOs and 1.8 ± 0.1 time more likely in QSOs having black holes with masses larger than 1.23 × 10 9 M ☉ than in those with lower-mass black holes; and (4) there is excess flux in [O II]λ3727 emission in the composite spectra of the AAS samples compared with those of the control samples, which is at the emission redshift. The presence of AAS enhances the O II emission from the active galactic nucleus and/or the host galaxy. This excess is similar for both RD and RUD samples and is 2.5 ± 0.4 times higher in lobe-dominated samples than in core-dominated samples. The excess depends on the black hole mass and Eddington ratio. All these point to the intrinsic nature of the AAS except for the systems with z abs > z em , which could be infalling galaxies.

  15. Thermodynamic modelling and parametric study of a low temperature vapour compression-absorption system based on modified Gouy-Stodola equation

    International Nuclear Information System (INIS)

    Jain, Vaibhav; Sachdeva, Gulshan; Kachhwaha, S.S.

    2015-01-01

    Present paper thermodynamically analyses a VCAS (vapour compression-absorption system) with carbon dioxide (compression section) and ammonia-water (absorption section) as refrigerants and determines the optimal condensing temperature of cascade condenser using modified Gouy-Stodola equation. The optimum cascade condenser temperature is found to be −13 °C for 175 kW refrigeration capacity at an evaporator temperature of −45 °C and condenser temperature of 35 °C. The optimum cascade condenser temperature maximises the overall COP, rational efficiency and minimises the total irreversibility rate of the VCAS system. The value of optimum condensing temperature and its corresponding maximum COP, and minimum irreversibility rate are discussed for a wide range of operating conditions. Further, a comparative study of TSVCS (two stage vapour compression system) used for low temperature refrigeration applications with VCAS shows that at design point, primary energy consumption is reduced by 60.6% and electrical COP is improved by 153.6% in VCAS as compared to conventional TSVCS. But the total irreversibility rate of VCAS is 38.4% higher than the TSVCS due to the use of low grade energy in vapour absorption system and hence the rational efficiency of VCAS is 14% low. - Highlights: • Optimum cascade condenser temperature with modified Gouy-Stodola law is analysed. • It maximises COP, rational efficiency and minimises total irreversibility. • 60.6% of primary energy is saved by cascaded absorption system. • Electrical COP is improved by 153.6% with cascaded absorption system

  16. Alpha detection on moving surfaces

    International Nuclear Information System (INIS)

    MacArthur, D.; Orr, C.; Luff, C.

    1998-01-01

    Both environmental restoration (ER) and decontamination and decommissioning (D and D) require characterization of large surface areas (walls, floors, in situ soil, soil and rubble on a conveyor belt, etc.) for radioactive contamination. Many facilities which have processed alpha active material such as plutonium or uranium require effective and efficient characterization for alpha contamination. Traditional methods for alpha surface characterization are limited by the short range and poor penetration of alpha particles. These probes are only sensitive to contamination located directly under the probe. Furthermore, the probe must be held close to the surface to be monitored in order to avoid excessive losses in the ambient air. The combination of proximity and thin detector windows can easily cause instrument damage unless extreme care is taken. The long-range alpha detection (LRAD) system addresses these problems by detecting the ions generated by alpha particles interacting with ambient air rather than the alpha particle directly. Thus, detectors based on LRAD overcome the limitations due to alpha particle range (the ions can travel many meters as opposed to the several-centimeter alpha particle range) and penetrating ability (an LRAD-based detector has no window). Unfortunately, all LRAD-based detectors described previously are static devices, i.e., these detectors cannot be used over surfaces which are continuously moving. In this paper, the authors report on the first tests of two techniques (the electrostatic ion seal and the gridded electrostatic LRAD detector) which extend the capabilities of LRAD surface monitors to use over moving surfaces. This dynamic surface monitoring system was developed jointly by Los Alamos National Laboratory and at BNFL Instruments. All testing was performed at the BNFL Instruments facility in the UK

  17. Investigation of structural and hydrogen absorption properties in the LaNi5-xPtx-H2 system

    International Nuclear Information System (INIS)

    Joubert, J.-M.; Charton, J.; Percheron-Guegan, A.

    2003-01-01

    The substitution of nickel by platinum in the binary LaNi 5 compound (CaCu 5 structure type, a=5.019(1) A, c=3.981(1) A, space group P6/mmm) and its effect on the hydrogenation properties was studied. The phase LaNi 5-x Pt x has a homogeneity domain ranging from x=0 to 5. For x 3. Contrary to what is observed in other systems, the hydrogen absorption plateau pressure was found to increase as a function of the cell volume. Powder neutron diffraction experiments were conducted for two deuterated compounds with x=0.25 and 0.75. Deuterium partial ordering occurs in the case of x=0.25 leading to a symmetry decrease to the space group P6mm (LaNi 4.75 Pt 0.25 D 5.23 , a=4.225(1) A, c=5.357(1) A, Z=1, R Bragg =3.3%). For x=0.75, an orthorhombic superstructure based on the CaCu 5 -type lattice was found (LaNi 4.25 Pt 0.75 D 2.61 , a orth =√3a hex =9.089(1) A, b orth =b hex =5.272(1) A, c orth =2c hex =8.145(1) A, Z=4, SG Ibam, R Bragg =6.1%)

  18. Absorption systems at z ˜ 2 as a probe of the circum galactic medium: a probabilistic approach

    Science.gov (United States)

    Mongardi, C.; Viel, M.; D'Odorico, V.; Kim, T.-S.; Barai, P.; Murante, G.; Monaco, P.

    2018-05-01

    We characterize the properties of the intergalactic medium (IGM) around a sample of galaxies extracted from state-of-the-art hydrodynamical simulations of structure formation in a cosmological volume of 25 Mpc comoving at z ˜ 2. The simulations are based on two different sub-resolution schemes for star formation and supernova feedback: the MUlti-Phase Particle Integrator (MUPPI) scheme and the Effective Model. We develop a quantitative and probabilistic analysis based on the apparent optical depth method of the properties of the absorbers as a function of impact parameter from their nearby galaxies: in such a way we probe different environments from circumgalactic medium (CGM) to low density filaments. Absorbers' properties are then compared with a spectroscopic observational data set obtained from high resolution quasar spectra. Our main focus is on the NCIV - NHI relation around simulated galaxies: the results obtained with MUPPI and the Effective model are remarkably similar, with small differences only confined to regions at impact parameters b = [1 - 3] × rvir. Using {C IV} as a tracer of the metallicity, we obtain evidence that the observed metal absorption systems have the highest probability to be confined in a region of 150-400 kpc around galaxies. Near-filament environments have instead metallicities too low to be probed by present-day telescopes, but could be probed by future spectroscopical studies. Finally we compute {C IV} covering fractions which are in agreement with observational data.

  19. A possible connection between the spin temperature of damped Lyman α absorption systems and star formation history

    Science.gov (United States)

    Curran, S. J.

    2017-09-01

    We present a comprehensive analysis of the spin temperature/covering factor degeneracy, Tspin/f, in damped Lyman α absorption systems. By normalizing the upper limits and including these via a survival analysis, there is, as previously claimed, an apparent increase in Tspin/f with redshift at zabs ≳ 1. However, when we account for the geometry effects of an expanding Universe, neglected by the previous studies, this increase in Tspin at zabs ≳ 1 is preceded by a decrease at zabs ≲ 1. Using high resolution radio images of the background continuum sources, we can transform the Tspin/f degeneracy to T_spin/d_abs^{ 2}, where dabs is the projected linear size of the absorber. Again, there is no overall increase with redshift, although a dip at zabs ≈ 2 persists. Furthermore, we find d_abs^{ 2}/T_spin to follow a similar variation with redshift as the star formation rate, ψ*. This suggests that, although the total hydrogen column density, N_{H I}, shows little relation to ψ*, the fraction of the cold neutral medium, \\int τ_obs dv/N_{H I}, may. Therefore, further efforts to link the neutral gas with the star formation history should also consider the cool component of the gas.

  20. The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)

    DEFF Research Database (Denmark)

    Michaelsen, Maria Hotoft; Wasan, Kishor M.; Sivak, Olena

    2016-01-01

    A super-saturated self-nanoemulsifying drug delivery system (super-SNEDDS), containing the poorly water-soluble drug halofantrine (Hf) at 150% of equilibrium solubility (Seq), was compared in vitro and in vivo with a conventional SNEDDS (75% of Seq) with respect to bioavailability and digestibility....... Further, the effect of digestion on oral absorption of Hf from SNEDDS and super-SNEDDS was assessed by incorporation of the lipase inhibitor tetrahydrolipstatin (orlistat) into the SNEDDS. The SNEDDS contained soybean oil/Maisine 34-I (1:1), Kolliphor RH40, and ethanol at a ratio of 55:35:10, w/w percent....... For the dynamic in vitro lipolysis, the precipitation of Hf at 60 min was significantly larger for the super-SNEDDS (66.8 ± 16.4%) than for the SNEDDS (18.5 ± 9.2%). The inhibition of the in vitro digestion by orlistat (1% (w/w)) lowered drug precipitation significantly for both the super-SNEDDS (36.8 ± 1...

  1. Experimental diagnosis of the influence of operational variables on the performance of a solar absorption cooling system

    International Nuclear Information System (INIS)

    Venegas, M.; Rodriguez-Hidalgo, M.C.; Salgado, R.; Lecuona, A.; Rodriguez, P.; Gutierrez, G.

    2011-01-01

    This paper presents the analysis of the performance of a solar cooling facility along one summer season using a commercial single-effect water-lithium bromide absorption chiller aiming at domestic applications. The facility works only with solar energy using flat plate collectors and it is located at Universidad Carlos III de Madrid, Spain. The statistical analysis performed with the gathered data shows the influence of five daily operational variables on the system performance. These variables are solar energy received along the day (H) and the average values, along the operating period of the solar cooling facility (from sunrise to the end of the cold-water production), of the ambient temperature (T -bar ), the wind velocity magnitude (V), the wind direction (θ) and the relative humidity (RH). First order correlation functions are given. The analysis of the data allows concluding that the most influential variables on the daily cooling energy produced and the daily averaged solar COP are H, V and θ. The period length of cold-water production is determined mainly by H and T -bar .

  2. Experimental diagnosis of the influence of operational variables on the performance of a solar absorption cooling system

    Energy Technology Data Exchange (ETDEWEB)

    Venegas, M.; Rodriguez-Hidalgo, M.C.; Lecuona, A.; Rodriguez, P.; Gutierrez, G. [Dpto. Ingenieria Termica y de Fluidos, Universidad Carlos III de Madrid, Avda. Universidad 30, 28911 Leganes, Madrid (Spain); Salgado, R. [Dpto. Ingenieria Mecanica, Universidad Interamericana de Puerto Rico, Recinto de Bayamon, 500 Carretera Dr. John Will Harris Bayamon, PR 00957-6257 (United States)

    2011-04-15

    This paper presents the analysis of the performance of a solar cooling facility along one summer season using a commercial single-effect water-lithium bromide absorption chiller aiming at domestic applications. The facility works only with solar energy using flat plate collectors and it is located at Universidad Carlos III de Madrid, Spain. The statistical analysis performed with the gathered data shows the influence of five daily operational variables on the system performance. These variables are solar energy received along the day (H) and the average values, along the operating period of the solar cooling facility (from sunrise to the end of the cold-water production), of the ambient temperature (anti T), the wind velocity magnitude (V), the wind direction ({theta}) and the relative humidity (RH). First order correlation functions are given. The analysis of the data allows concluding that the most influential variables on the daily cooling energy produced and the daily averaged solar COP are H, V and {theta}. The period length of cold-water production is determined mainly by H and anti T. (author)

  3. Radionuclide Absorption Demonstration System

    Data.gov (United States)

    National Aeronautics and Space Administration — After a nuclear thermal rocket (NTR) is test fired, the engine’s reactor is operated in a cool-down mode during which radioactive exhaust by-products continue to be...

  4. Alpha scintillation radon counting

    International Nuclear Information System (INIS)

    Lucas, H.F. Jr.

    1977-01-01

    Radon counting chambers which utilize the alpha-scintillation properties of silver activated zinc sulfide are simple to construct, have a high efficiency, and, with proper design, may be relatively insensitive to variations in the pressure or purity of the counter filling. Chambers which were constructed from glass, metal, or plastic in a wide variety of shapes and sizes were evaluated for the accuracy and the precision of the radon counting. The principles affecting the alpha-scintillation radon counting chamber design and an analytic system suitable for a large scale study of the 222 Rn and 226 Ra content of either air or other environmental samples are described. Particular note is taken of those factors which affect the accuracy and the precision of the method for monitoring radioactivity around uranium mines

  5. Innovations in Los Alamos alpha box design

    International Nuclear Information System (INIS)

    Ledbetter, J.M.; Dowler, K.E.; Cook, J.H.

    1985-01-01

    Destructive examinations of irradiated fuel pins containing plutonium fuel must be performed in shielded hot cells with strict provisions for containing the plutonium. Alpha boxes provide containment for the plutonium, toxic fission products, and other hazardous highly radioactive materials. The alpha box contains windows for viewing and a variety of transfer systems specially designed to allow transfers in and out of the alpha box without spread of the hazardous materials that are contained in the box. Alpha boxes have been in use in the Wing 9 hot cells at Los Alamos National Laboratory for more than 20 years. Features of the newly designed alpha boxes are presented

  6. Deglycosylation of serum vitamin D3-binding protein by alpha-N-acetylgalactosaminidase detected in the plasma of patients with systemic lupus erythematosus.

    Science.gov (United States)

    Yamamoto, N; Naraparaju, V R; Moore, M; Brent, L H

    1997-03-01

    A serum glycoprotein, Gc protein (vitamin D3-binding protein), can be converted by beta-galactosidase of B cells and sialidase of T cells to a potent macrophage-activating factor (MAF), a protein with N-acetylgalactosamine as the remaining sugar moiety. Thus, Gc protein is the precursor for MAF. Treatment of Gc protein with immobilized beta-galactosidase and sialidase generates a remarkably high titered macrophage-activating factor (GcMAF). When peripheral blood monocytes/ macrophages (designated macrophages) of 33 systemic lupus erythematosus patients were incubated with GcMAF (100 pg/ml), the macrophages of all patients were activated as determined by superoxide generation. However, the precursor activity of patient plasma Gc protein was lost or reduced in these patients. Loss of the precursor activity was the result of deglycosylation of plasma Gc protein by alpha-N-acetylgalactosaminidase activity found in the patient plasma. Levels of plasma alpha-N-acetylgalactosaminidase activity in individual patients had an inverse correlation with the MAF precursor activity of their plasma Gc protein. Deglycosylated Gc protein cannot be converted to macro-phage-activating factor. The resulting defect in macro-phage activation may lead to an inability to clear pathogenic immune complexes. Thus, elevated plasma alpha-N-acetylgalactosaminidase activity resulting in the loss of MAF precursor activity and reduced macro-phage activity may play a role in the pathogenesis of systemic lupus erythematosus.

  7. Effect of coexistent hydrogen isotopes on tracer diffusion of tritium in alpha phase of group-V metal-hydrogen systems

    International Nuclear Information System (INIS)

    Sakamoto, Kan; Hashizume, Kenichi; Sugisaki, Masayasu

    2009-01-01

    Tracer diffusion coefficients of tritium in the alpha phase of group-V metal-hydrogen systems, α-MH(D)xTy (M=V and Ta; x>>y), were measured in order to clarify the effects of coexistent hydrogen isotopes on the tritium diffusion behavior. The hydrogen concentration dependence of such behavior and the effects of the coexistent hydrogen isotopes (protium and deuterium) were determined. The results obtained in the present (for V and Ta) and previous (for Nb) studies revealed that tritium diffusion was definitely dependent on hydrogen concentration but was not so sensitive to the kind of coexistent hydrogen isotopes. By summarizing those data, it was found that the hydrogen concentration dependence of the tracer diffusion coefficient of tritium in the alpha phase of group-V metals could be roughly expressed by a single empirical curve. (author)

  8. Structural determination of individual chemical species in a mixed system by iterative transformation factor analysis-based X-ray absorption spectroscopy combined with UV-visible absorption and quantum chemical calculation.

    Science.gov (United States)

    Ikeda, Atsushi; Hennig, Christoph; Rossberg, André; Tsushima, Satoru; Scheinost, Andreas C; Bernhard, Gert

    2008-02-15

    A multitechnique approach using extended X-ray absorption fine structure (EXAFS) spectroscopy based on iterative transformation factor analysis (ITFA), UV-visible absorption spectroscopy, and density functional theory (DFT) calculations has been performed in order to investigate the speciation of uranium(VI) nitrate species in acetonitrile and to identify the complex structure of individual species in the system. UV-visible spectral titration suggests that there are four different species in the system, that is, pure solvated species, mono-, di-, and trinitrate species. The pure EXAFS spectra of these individual species are extracted by ITFA from the measured spectral mixtures on the basis of the speciation distribution profile calculated from the UV-visible data. Data analysis of the extracted EXAFS spectra, with the help of DFT calculations, reveals the most probable complex structures of the individual species. The pure solvated species corresponds to a uranyl hydrate complex with an equatorial coordination number (CNeq) of 5, [UO2(H2O)5]2+. Nitrate ions tend to coordinate to the uranyl(VI) ion in a bidentate fashion rather than a unidentate one in acetonitrile for all the nitrate species. The mononitrate species forms the complex of [UO2(H2O)3NO3]+ with a CNeq value of 5, while the di- and trinitrate species have a CNeq value of 6, corresponding to [UO2(H2O)2(NO3)2]0 (D2h) and [UO2(NO3)3]- (D3h), respectively.

  9. Gamma–Gamma Absorption in the γ-ray Binary System PSR B1259-63/LS 2883

    Energy Technology Data Exchange (ETDEWEB)

    Sushch, Iurii [Centre for Space Research, North-West University, 2520 Potcheftroom (South Africa); Van Soelen, Brian, E-mail: iurii.sushch@desy.de, E-mail: vansoelenb@ufs.ac.za [Department of Physics, University of the Free State, 9300 Bloemfontein (South Africa)

    2017-03-10

    The observed TeV light curve from the γ -ray binary PSR B1259-63/LS 2883 shows a decrease in the flux at periastron that has not been fully explained by emission mechanisms alone. This observed decrease can, however, be explained by γγ absorption due to the stellar and disk photons. We calculate the γγ absorption in PSR B1259-63/LS 2883 taking into account photons from both the circumstellar disk and star, assuming that the γ -rays originate at the position of the pulsar. The γγ absorption due to the circumstellar disk photons produces a ≈14% decrease in the flux, and there is a total decrease of ≈52% (>1 TeV) within a few days before periastron, accompanied by a hardening of the γ -ray photon index. While the γγ absorption alone is not sufficient to explain the full complexity of the H.E.S.S. γ -ray light curve, it results in a significant decrease in the predicted flux, which is coincident with the observed decrease. In addition, we have calculated an upper limit on the γγ absorption, assuming that the emission is produced at the apex of the bow shock. Future observations with CTA during the 2021 periastron passage may be able to confine the location of the emission based on the degree of γγ absorption, as well as measure the hardening of the spectrum around periastron.

  10. Comparison of two methods for blood lead analysis in cattle: graphite-furnace atomic absorption spectrometry and LeadCare(R) II system.

    Science.gov (United States)

    Bischoff, Karyn; Gaskill, Cynthia; Erb, Hollis N; Ebel, Joseph G; Hillebrandt, Joseph

    2010-09-01

    The current study compared the LeadCare(R) II test kit system with graphite-furnace atomic absorption spectrometry for blood lead (Pb) analysis in 56 cattle accidentally exposed to Pb in the field. Blood Pb concentrations were determined by LeadCare II within 4 hr of collection and after 72 hr of refrigeration. Blood Pb concentrations were determined by atomic absorption spectrometry, and samples that were coagulated (n = 12) were homogenized before analysis. There was strong rank correlation (R(2) = 0.96) between atomic absorption and LeadCare II (within 4 hr of collection), and a conversion formula was determined for values within the observed range (3-91 mcg/dl, although few had values >40 mcg/dl). Median and mean blood pb concentrations for atomic absorption were 7.7 and 15.9 mcg/dl, respectively; for LeadCare II, medians were 5.2 mcg/dl at 4 hr and 4.9 mcg/dl at 72 hr, and means were 12.4 and 11.7, respectively. LeadCare II results at 4 hr strongly correlated with 72 hr results (R(2) = 0.96), but results at 72 hr were lower (P atomic absorption. Although there have been several articles that compared LeadCare with other analytical techniques, all were for the original system, not LeadCare II. The present study indicated that LeadCare II results correlated well with atomic absorption over a wide range of blood Pb concentrations and that refrigerating samples for up to 72 hr before LeadCare II analysis was acceptable for clinical purposes.

  11. Alpha particle analysis using PEARLS spectrometry

    International Nuclear Information System (INIS)

    McKlveen, J.W.; Klingler, G.W.; McDowell, W.J.; Case, G.N.

    1984-01-01

    Alpha particle assay by conventional plate-counting methods is difficult because chemical separation, tracer techniques, and/or self-absorption losses in the final sample may cause either non-reproducible results or create unacceptable errors. PEARLS (Photon-Electron Rejecting Alpha Liquid Scintillation) Spectrometry is an attractive alternative since radionuclides may be extracted into a scintillator in which there would be no self-absorption or geometry problems and in which up to 100% chemical recovery and counting efficiency is possible. Sample preparation may include extraction of the alpha emitter of interest by a specific organic-phase-soluble compound directly into the liquid scintillator. Detection electronics use energy and pulse-shape discrimination to provide discrete alpha spectra and virtual absence of beta and gamma backgrounds. Backgrounds on the order of 0.01 cpm are readily achievable. Accuracy and reproducibility are typically in the 100 +-1% range. Specific procedures have been developed for gross alpha, uranium, plutonium, thorium, and polonium assay. This paper will review liquid scintillation alpha counting methods and reference some of the specific applications. 8 refs., 1 fig

  12. Enabling the Distributed Generation Market of High Temperature Fuel Cell and Absorption Chiller Systems to Support Critical and Commercial Loads

    Science.gov (United States)

    DiMola, Ashley M.

    Buildings account for over 18% of the world's anthropogenic Greenhouse Gas (GHG) emissions. As a result, a technology that can offset GHG emissions associated with buildings has the potential to save over 9 Giga-tons of GHG emissions per year. High temperature fuel cell and absorption chiller (HTFC/AC) technology offers a relatively low-carbon option for meeting cooling and electric loads for buildings while producing almost no criteria pollutants. GHG emissions in the state of California would decrease by 7.48 million metric tons per year if every commercial building in the State used HTFC/AC technology to meet its power and cooling requirements. In order to realize the benefits of HTFC/AC technology on a wide scale, the distributed generation market needs to be exposed to the technology and informed of its economic viability and real-world potential. This work characterizes the economics associated with HTFC/AC technology using select scenarios that are representative of realistic applications. The financial impacts of various input factors are evaluated and the HTFC/AC simulations are compared to the economics of traditional building utilities. It is shown that, in addition to the emissions reductions derived from the systems, HTFC/AC technology is financially preferable in all of the scenarios evaluated. This work also presents the design of a showcase environment, centered on a beta-test application, that presents (1) system operating data gathered using a custom data acquisition module, and (2) HTFC/AC technology in a clear and approachable manner in order to serve the target audience of market stakeholders.

  13. Extrapolation of systemic bioavailability assessing skin absorption and epidermal and hepatic metabolism of aromatic amine hair dyes in vitro

    Energy Technology Data Exchange (ETDEWEB)

    Manwaring, John, E-mail: manwaring.jd@pg.com [Procter & Gamble Inc., Mason Business Center, Mason, OH 45040 (United States); Rothe, Helga [Procter & Gamble Service GmbH, Sulzbacher Str. 40, 65823 Schwalbach am Taunus (Germany); Obringer, Cindy; Foltz, David J.; Baker, Timothy R.; Troutman, John A. [Procter & Gamble Inc., Mason Business Center, Mason, OH 45040 (United States); Hewitt, Nicola J. [SWS, Erzhausen (Germany); Goebel, Carsten [Procter & Gamble Service GmbH, Sulzbacher Str. 40, 65823 Schwalbach am Taunus (Germany)

    2015-09-01

    Approaches to assess the role of absorption, metabolism and excretion of cosmetic ingredients that are based on the integration of different in vitro data are important for their safety assessment, specifically as it offers an opportunity to refine that safety assessment. In order to estimate systemic exposure (AUC) to aromatic amine hair dyes following typical product application conditions, skin penetration and epidermal and systemic metabolic conversion of the parent compound was assessed in human skin explants and human keratinocyte (HaCaT) and hepatocyte cultures. To estimate the amount of the aromatic amine that can reach the general circulation unchanged after passage through the skin the following toxicokinetically relevant parameters were applied: a) Michaelis–Menten kinetics to quantify the epidermal metabolism; b) the estimated keratinocyte cell abundance in the viable epidermis; c) the skin penetration rate; d) the calculated Mean Residence Time in the viable epidermis; e) the viable epidermis thickness and f) the skin permeability coefficient. In a next step, in vitro hepatocyte K{sub m} and V{sub max} values and whole liver mass and cell abundance were used to calculate the scaled intrinsic clearance, which was combined with liver blood flow and fraction of compound unbound in the blood to give hepatic clearance. The systemic exposure in the general circulation (AUC) was extrapolated using internal dose and hepatic clearance, and C{sub max} was extrapolated (conservative overestimation) using internal dose and volume of distribution, indicating that appropriate toxicokinetic information can be generated based solely on in vitro data. For the hair dye, p-phenylenediamine, these data were found to be in the same order of magnitude as those published for human volunteers. - Highlights: • An entirely in silico/in vitro approach to predict in vivo exposure to dermally applied hair dyes • Skin penetration and epidermal conversion assessed in human

  14. Extrapolation of systemic bioavailability assessing skin absorption and epidermal and hepatic metabolism of aromatic amine hair dyes in vitro

    International Nuclear Information System (INIS)

    Manwaring, John; Rothe, Helga; Obringer, Cindy; Foltz, David J.; Baker, Timothy R.; Troutman, John A.; Hewitt, Nicola J.; Goebel, Carsten

    2015-01-01

    Approaches to assess the role of absorption, metabolism and excretion of cosmetic ingredients that are based on the integration of different in vitro data are important for their safety assessment, specifically as it offers an opportunity to refine that safety assessment. In order to estimate systemic exposure (AUC) to aromatic amine hair dyes following typical product application conditions, skin penetration and epidermal and systemic metabolic conversion of the parent compound was assessed in human skin explants and human keratinocyte (HaCaT) and hepatocyte cultures. To estimate the amount of the aromatic amine that can reach the general circulation unchanged after passage through the skin the following toxicokinetically relevant parameters were applied: a) Michaelis–Menten kinetics to quantify the epidermal metabolism; b) the estimated keratinocyte cell abundance in the viable epidermis; c) the skin penetration rate; d) the calculated Mean Residence Time in the viable epidermis; e) the viable epidermis thickness and f) the skin permeability coefficient. In a next step, in vitro hepatocyte K m and V max values and whole liver mass and cell abundance were used to calculate the scaled intrinsic clearance, which was combined with liver blood flow and fraction of compound unbound in the blood to give hepatic clearance. The systemic exposure in the general circulation (AUC) was extrapolated using internal dose and hepatic clearance, and C max was extrapolated (conservative overestimation) using internal dose and volume of distribution, indicating that appropriate toxicokinetic information can be generated based solely on in vitro data. For the hair dye, p-phenylenediamine, these data were found to be in the same order of magnitude as those published for human volunteers. - Highlights: • An entirely in silico/in vitro approach to predict in vivo exposure to dermally applied hair dyes • Skin penetration and epidermal conversion assessed in human skin explants and

  15. Hypothalamic PGC-1 alpha Protects Against High-Fat Diet Exposure by Regulating ER alpha

    NARCIS (Netherlands)

    Morselli, Eugenia; Fuente-Martin, Esther; Finan, Brian; Kim, Min; Frank, Aaron; Garcia-Caceres, Cristina; Navas, Carlos Rodriguez; Gordillo, Ruth; Neinast, Michael; Kalainayakan, Sarada P.; Li, Dan L.; Gao, Yuanqing; Yi, Chun-Xia; Hahner, Lisa; Palmer, Biff F.; Tschöp, Matthias H.; Clegg, Deborah J.

    2014-01-01

    High-fat diets (HFDs) lead to obesity and inflammation in the central nervous system (CNS). Estrogens and estrogen receptor alpha (ER alpha) protect premenopausal females from the metabolic complications of inflammation and obesity-related disease. Here, we demonstrate that hypothalamic PGC-1 alpha

  16. GAS MOTION STUDY OF Ly{alpha} EMITTERS AT z {approx} 2 USING FUV AND OPTICAL SPECTRAL LINES {sup ,}

    Energy Technology Data Exchange (ETDEWEB)

    Hashimoto, Takuya; Shimasaku, Kazuhiro; Nakajima, Kimihiko [Department of Astronomy, Graduate School of Science, The University of Tokyo, Tokyo 113-0033 (Japan); Ouchi, Masami; Ono, Yoshiaki [Institute for Cosmic Ray Research, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8582 (Japan); Rauch, Michael; Janice Lee [Observatories of the Carnegie Institution of Washington, 813 Santa Barbara Street, Pasadena, CA 91101 (United States); Okamura, Sadanori, E-mail: thashimoto@astron.s.u-tokyo.ac.jp [Department of Advanced Sciences, Faculty of Science and Engineering, Hosei University, 3-7-2 Kajino-cho, Koganei-shi, Tokyo 184-8584 (Japan)

    2013-03-01

    We present the results of Magellan/MMIRS and Keck/NIRSPEC spectroscopy for five Ly{alpha} emitters (LAEs) at z {approx_equal} 2.2 for which high-resolution FUV spectra from Magellan/MagE are available. We detect nebular emission lines including H{alpha} on the individual basis and low-ionization interstellar (LIS) absorption lines in a stacked FUV spectrum, and measure average offset velocities of the Ly{alpha} line, {Delta}v {sub Ly{alpha}}, and LIS absorption lines, {Delta}v {sub abs}, with respect to the systemic velocity defined by the nebular lines. For a sample of eight z {approx} 2-3 LAEs without active galactic nucleus from our study and the literature, we obtain {Delta}v {sub Ly{alpha}} = 175 {+-} 35 km s{sup -1}, which is significantly smaller than that of Lyman-break Galaxies (LBGs), {Delta}v {sub Ly{alpha}} {approx_equal} 400 km s{sup -1}. The stacked FUV spectrum gives {Delta}v {sub abs} = -179 {+-} 73 km s{sup -1}, comparable to that of LBGs. These positive {Delta}v {sub Ly{alpha}} and negative {Delta}v {sub abs} suggest that LAEs also have outflows. In contrast to LBGs, however, the LAEs' {Delta}v {sub Ly{alpha}} is as small as |{Delta}v {sub abs}|, suggesting low neutral hydrogen column densities. Such a low column density with a small number of resonant scattering may cause the observed strong Ly{alpha} emission of LAEs. We find an anti-correlation between Ly{alpha} equivalent width (EW) and {Delta}v {sub Ly{alpha}} in a compilation of LAE and LBG samples. Although its physical origin is not clear, this anti-correlation result appears to challenge the hypothesis that a strong outflow, by means of a reduced number of resonant scattering, produces a large EW. If LAEs at z > 6 have similarly small {Delta}v {sub Ly{alpha}} values, constraints on the reionization history derived from the Ly{alpha} transmissivity may need to be revised.

  17. Study of a Steel’s Energy Absorption System for Heavy Quadricycles and Nonlinear Explicit Dynamic Analysis of its Behavior under Impact by FEM

    Science.gov (United States)

    López Campos, José Ángel; Segade Robleda, Abraham; Vilán Vilán, José Antonio; García Nieto, Paulino José; Blanco Cordero, Javier

    2015-01-01

    Current knowledge of the behavior of heavy quadricycles under impact is still very poor. One of the most significant causes is the lack of energy absorption in the vehicle frame or its steel chassis structure. For this reason, special steels (with yield stresses equal to or greater than 350 MPa) are commonly used in the automotive industry due to their great strain hardening properties along the plastic zone, which allows good energy absorption under impact. This paper presents a proposal for a steel quadricycle energy absorption system which meets the percentages of energy absorp