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Sample records for alpha decay chains

  1. First observation of /sup 162/Hf decay completion of an alpha -decay chain

    CERN Document Server

    Schrewe, U J; Hagberg, E; Hardy, J C; Koslowsky, V T; Schmeing, H; Sharma, K S

    1981-01-01

    The new isotope /sup 162/Hf (T/sub 1/2/=(37.6+or-0.8)s) is produced in a /sup 142/Nd (/sup 24/Mg,4n) reaction. The activities produced in this reaction are transported to a measuring station by use of a He- jet system. Decay properties are observed with alpha -, gamma -, and gamma - gamma -spectroscopy. The Z-assignment of the new isotope is based on a cross bombardment on /sup 141/Pr target and on the results of a gamma -X-ray coincidence measurement. The mass assignment is deduced from the excitation function measurements. From the measured alpha -decay energy E/sub alpha /=4308 (10) keV new mass values are derived for /sup 162/Hf, /sup 166/W, /sup 170/Os, /sup 174/Pt, and /sup 178/Hg. These new mass values make it possible to establish systematics of two-proton and one-proton binding energies far from stability. (20 refs).

  2. Structure effects in the region of superheavy elements via the alpha-decay chain of sup 2 sup 9 sup 3 118

    CERN Document Server

    Gupta, R K; Kumar, R; Balasubramaniam, M; Scheid, W

    2002-01-01

    The alpha-decay chain of sup 2 sup 9 sup 3 118, first proposed in the Berkeley cold fusion experiment sup 2 sup 0 sup 8 Pb( sup 8 sup 6 Kr, 1n) and now retracted, is calculated by using the preformed cluster model (PCM) of one of the authors (RKG). Also, the possible branchings of alpha-decays to heavier cluster decays of all the parents in this chain are calculated for the first time. The calculated Q-values, penetrabilities and preformation factors for alpha-decays suggest that the sup 2 sup 8 sup 5 114 nucleus with Z=114, N=171 is a magic nucleus, either due to the magicity of Z=114, or N=172 or both. The N=172 is proposed to be a magic number in certain relativistic mean-field calculations, but with Z 120. The calculated cluster decays point to new interesting possibilities of sup 1 sup 4 C decay of the sup 2 sup 8 sup 1 112 parent, giving rise to a (reasonably) deformed Z=106, N=161, sup 2 sup 6 sup 7 106 daughter (N=162 being now established as the deformed magic shell) or to a doubly magic sup 4 sup 8 ...

  3. WAD, a program to calculate the heat produced by alpha decay

    International Nuclear Information System (INIS)

    Jarvis, R.G.; Bretzlaff, C.I.

    1982-09-01

    The FORTRAN program WAD (Watts from Alpha Decay) deals with the alpha and beta decay chains to be encountered in advanced fuel cycles for CANDU reactors. The data library covers all necessary alpha-emitting and beta-emitting nuclides and the program calculates the heat produced by alpha decay. Any permissible chain can be constructed very simply

  4. The analysis of predictability of recent alpha decay formulae and the alpha partial half-lives of some exotic nuclei

    International Nuclear Information System (INIS)

    Dasgupta-Schubert, N.; Reyes, M. A.; Tamez, V. A.

    2009-01-01

    Alpha decay is one of the two main decay modes of the heaviest nuclei, (SHE), and constitutes one of the dominant decay modes of highly neutron deficient medium mass nuclei ('exotics'). Thus identifying and characterizing the alpha decay chains form a crucial part of the identification of SHE. We report the extension of the previously developed method for the detailed and systematic investigation of the reliability of the three main extant analytical formulae of alpha decay half-lives: the generalized liquid drop model based formula of Royer et al. (FR), the Sobiczewski modified semi-empirical Viola-Seaborg formula (VSS) and the recent phenomenological formula of Sobiczewski and Parkhomenko (SP).

  5. Classification of decays involving variable decay chains with convolutional architectures

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    Vidyo contribution We present a technique to perform classification of decays that exhibit decay chains involving a variable number of particles, which include a broad class of $B$ meson decays sensitive to new physics. The utility of such decays as a probe of the Standard Model is dependent upon accurate determination of the decay rate, which is challenged by the combinatorial background arising in high-multiplicity decay modes. In our model, each particle in the decay event is represented as a fixed-dimensional vector of feature attributes, forming an $n \\times k$ representation of the event, where $n$ is the number of particles in the event and $k$ is the dimensionality of the feature vector. A convolutional architecture is used to capture dependencies between the embedded particle representations and perform the final classification. The proposed model performs outperforms standard machine learning approaches based on Monte Carlo studies across a range of variable final-state decays with the Belle II det...

  6. Single particle level scheme for alpha decay

    International Nuclear Information System (INIS)

    Mirea, M.

    1998-01-01

    The fine structure phenomenon in alpha decay was evidenced by Rosenblum. In this process the kinetic energy of the emitted particle has several determined values related to the structure of the parent and the daughter nucleus. The probability to find the daughter in a low lying state was considered strongly dependent on the spectroscopic factor defined as the square of overlap between the wave function of the parent in the ground state and the wave functions of the specific excited states of the daughter. This treatment provides a qualitative agreement with the experimental results if the variations of the penetrability between different excited states are neglected. Based on single particle structure during fission, a new formalism explained quantitatively the fine structure of the cluster decay. It was suggested that this formalism can be applied also to alpha decay. For this purpose, the first step is to construct the level scheme of this type of decay. Such a scheme, obtained with the super-asymmetric two-center potential, is plotted for the alpha decay of 223 Ra. It is interesting to note that, diabatically, the level with spin 3/2 emerging from 1i 11/2 (ground state of the parent) reaches an excited state of the daughter in agreement with the experiment. (author)

  7. Spectroscopy of element 115 decay chains.

    Science.gov (United States)

    Rudolph, D; Forsberg, U; Golubev, P; Sarmiento, L G; Yakushev, A; Andersson, L-L; Di Nitto, A; Düllmann, Ch E; Gates, J M; Gregorich, K E; Gross, C J; Heßberger, F P; Herzberg, R-D; Khuyagbaatar, J; Kratz, J V; Rykaczewski, K; Schädel, M; Åberg, S; Ackermann, D; Block, M; Brand, H; Carlsson, B G; Cox, D; Derkx, X; Eberhardt, K; Even, J; Fahlander, C; Gerl, J; Jäger, E; Kindler, B; Krier, J; Kojouharov, I; Kurz, N; Lommel, B; Mistry, A; Mokry, C; Nitsche, H; Omtvedt, J P; Papadakis, P; Ragnarsson, I; Runke, J; Schaffner, H; Schausten, B; Thörle-Pospiech, P; Torres, T; Traut, T; Trautmann, N; Türler, A; Ward, A; Ward, D E; Wiehl, N

    2013-09-13

    A high-resolution α, x-ray, and γ-ray coincidence spectroscopy experiment was conducted at the GSI Helmholtzzentrum für Schwerionenforschung. Thirty correlated α-decay chains were detected following the fusion-evaporation reaction 48Ca + 243Am. The observations are consistent with previous assignments of similar decay chains to originate from element Z=115. For the first time, precise spectroscopy allows the derivation of excitation schemes of isotopes along the decay chains starting with elements Z>112. Comprehensive Monte Carlo simulations accompany the data analysis. Nuclear structure models provide a first level interpretation.

  8. Cluster and alpha decay of superheavy nuclei

    Science.gov (United States)

    Poenaru, D. N.; Stöcker, H.; Gherghescu, R. A.

    2018-02-01

    We investigated cluster radioactivity and alpha decay of some superheavy nuclei with atomic numbers Z = 119, 120 , which may be produced in the future. Two models are used to calculate the half-lives against cluster radioactivity: ASAF (Analytical Super-Asymmetric Fission) and UNIV (Universal Formula). For α decay half-lives we are based on four models: ASAF, UNIV, semFIS (semi-empirical formula based on Fission Theory) and AKRA (first author Akrawy). The Q -values are calculated using the theoretical model of atomic masses WS10, which sometimes is called W4.

  9. Precise Calculation of Complex Radioactive Decay Chains

    National Research Council Canada - National Science Library

    Harr, Logan J

    2007-01-01

    ...). An application of the exponential moments function is used with a transmutation matrix in the calculation of complex radioactive decay chains to achieve greater precision than can be attained through current methods...

  10. The analysis of predictability of recent alpha decay formulae and the alpha partial half-lives of some exotic nuclei

    Science.gov (United States)

    Dasgupta-Schubert, N.; Reyes, M. A.; Tamez, V. A.

    2009-04-01

    Alpha decay is one of the two main decay modes of the heaviest nuclei, (SHE), and constitutes one of the dominant decay modes of highly neutron deficient medium mass nuclei ("exotics"). Thus identifying and characterizing the alpha decay chains form a crucial part of the identification of SHE. We report the extension of the previously developed method [1] for the detailed and systematic investigation of the reliability of the three main extant analytical formulae of alpha decay half-lives: the generalized liquid drop model based formula of Royer et al. [2] (FR), the Sobiczewski modified semi-empirical Viola-Seaborg formula [3] (VSS) and the recent phenomenological formula of Sobiczewski and Parkhomenko [4] (SP).

  11. Decay times in one-dimensional chains

    International Nuclear Information System (INIS)

    Van den Broeck, C.; Bouten, M.

    1986-01-01

    The authors calculate the average residence time tau for a particle performing a random walk over a chain of N neighboring sites i = 1,..., N, with decay rates λ/sub i/ depending on the location of the particle in the chain. Exact results are given for some particular cases, while bounds on tau are given for specific initial conditions. In the continuum limit, various results from the literature are recovered or improved upon

  12. Energy-dependent etching-related impacts on CR-39 alpha detection efficiency for the Rn-222 and Rn-220 decay chains

    Science.gov (United States)

    Tan, Y.; Yuan, H.; Kearfott, K. J.

    2018-04-01

    CR-39 detectors are widely used to measure environmental levels of Rn-222, Rn-220 and their progeny. Prior research reported the CR-39 detection efficiency for alpha particles from Rn-222, Rn-220 and their progeny under a variety of etching conditions. This paper provides an explanation for interesting observations included in that work, namely that the critical incidence angle decreases with the increasing particle energy and the detection efficiency for 8.78 MeV alpha particles is zero. This paper explains these phenomena from a consideration of the interaction of alpha particles with the CR-39 detectors and the physics of etching dynamics. The proposed theory provides a rationale for an approach to optimizing the etching conditions of CR-39 detector for measuring Rn-222, Rn-220 and their progenies.

  13. Alpha decay calculations with a new formula

    Science.gov (United States)

    Akrawy, D. T.; Poenaru, D. N.

    2017-10-01

    A new semi-empirical formula for calculations of α decay half-lives is presented. It was derived from the Royer relationship by introducing new parameters which are fixed by fit to a set of experimental data. We are using three sets: set A with 130 e-e (even-even), 119 e-o (even-odd), 109 o-e, and 96 o-o, set B with 188 e-e, 147 e-o, 131 o-e and 114 o-o, and set C with 136 e-e, 84 e-o, 76 o-e and 48 o-o alpha emitters. A comparison of results obtained with the new formula (newF) and the following well known relationships: semiempirical relationship based on fission theory (semFIS), analytical superasymmetric fission (ASAF) model and universal formula (UNIV) made in terms of rms standard deviation. We also introduced a weighted mean value of this quantity, allowing us to compare the global properties of a given model. For set B the order of the four models is the following: semFIS, UNIV, newF and ASAF. Nevertheless for even-even alpha emitters, UNIV gives the second best result after semFIS, and for odd-even parents the second is newF. Despite its simplicity in comparison with semFIS, newF, presented in this article, behaves quite well, competing with the other well known relationships.

  14. Alpha decay calculations with a new formula

    International Nuclear Information System (INIS)

    Akrawy, D T; Poenaru, D N

    2017-01-01

    A new semi-empirical formula for calculations of α  decay half-lives is presented. It was derived from the Royer relationship by introducing new parameters which are fixed by fit to a set of experimental data. We are using three sets: set A with 130 e–e (even–even), 119 e–o (even–odd), 109 o–e, and 96 o–o, set B with 188 e–e, 147 e–o, 131 o–e and 114 o–o, and set C with 136 e–e, 84 e–o, 76 o–e and 48 o–o alpha emitters. A comparison of results obtained with the new formula (newF) and the following well known relationships: semiempirical relationship based on fission theory (semFIS), analytical superasymmetric fission (ASAF) model and universal formula (UNIV) made in terms of rms standard deviation. We also introduced a weighted mean value of this quantity, allowing us to compare the global properties of a given model. For set B the order of the four models is the following: semFIS, UNIV, newF and ASAF. Nevertheless for even–even alpha emitters, UNIV gives the second best result after semFIS, and for odd–even parents the second is newF. Despite its simplicity in comparison with semFIS, newF, presented in this article, behaves quite well, competing with the other well known relationships. (paper)

  15. Random numbers spring from alpha decay

    International Nuclear Information System (INIS)

    Frigerio, N.A.; Sanathanan, L.P.; Morley, M.; Clark, N.A.; Tyler, S.A.

    1980-05-01

    Congruential random number generators, which are widely used in Monte Carlo simulations, are deficient in that the number they generate are concentrated in a relatively small number of hyperplanes. While this deficiency may not be a limitation in small Monte Carlo studies involving a few variables, it introduces a significant bias in large simulations requiring high resolution. This bias was recognized and assessed during preparations for an accident analysis study of nuclear power plants. This report describes a random number device based on the radioactive decay of alpha particles from a 235 U source in a high-resolution gas proportional counter. The signals were fed to a 4096-channel analyzer and for each channel the frequency of signals registered in a 20,000-microsecond interval was recorded. The parity bits of these frequency counts (0 for an even count and 1 for an odd count) were then assembled in sequence to form 31-bit binary random numbers and transcribed to a magnetic tape. This cycle was repeated as many times as were necessary to create 3 million random numbers. The frequency distribution of counts from the present device conforms to the Brockwell-Moyal distribution, which takes into account the dead time of the counter (both the dead time and decay constant of the underlying Poisson process were estimated). Analysis of the count data and tests of randomness on a sample set of the 31-bit binary numbers indicate that this random number device is a highly reliable source of truly random numbers. Its use is, therefore, recommended in Monte Carlo simulations for which the congruential pseudorandom number generators are found to be inadequate. 6 figures, 5 tables

  16. Unified approach to alpha decay calculations

    Indian Academy of Sciences (India)

    2014-05-02

    May 2, 2014 ... With the discovery of a large number of superheavy nuclei undergoing decay through emissions, there has been a revival of interest in decay in recent years. In the theoretical study of decay the -nucleus potential, which is the basic input in the study of -nucleus systems, is also being studied using ...

  17. Alpha-decay within Feshbach theory of nuclear reactions

    International Nuclear Information System (INIS)

    Sandulescu, A.; Silisteanu, I.; Wunsch, R.

    1977-01-01

    In the frame of Feshbach theory of nuclear reactions the alpha-decay widths are determined by the alpha-daughter nucleus optical potential and by the formation factors. It is shown that the calculated absolute values of the alpha widths for Po light isotopes are in good agreement with experimental data, if the real part of the optical potential with the parameters fitted by the low energy α-scattering is used

  18. Superheavy-element spectroscopy: Correlations along element 115 decay chains

    Directory of Open Access Journals (Sweden)

    Rudolph D.

    2016-01-01

    Full Text Available Following a brief summary of the region of the heaviest atomic nuclei yet created in the laboratory, data on more than hundred α-decay chains associated with the production of element 115 are combined to investigate time and energy correlations along the observed decay chains. Several of these are analysed using a new method for statistical assessments of lifetimes in sets of decay chains.

  19. Unified approach to alpha decay calculations

    Indian Academy of Sciences (India)

    2014-05-02

    May 2, 2014 ... In the light of these, the Wentzel–Kramers–. Brillouin (WKB) approximation .... effective Coulomb barrier at energy E gives transmission coefficient T and hence, can be used to calculate decay ... In solving the Schrödinger equation for the radial wave function Rl(r) it is convenient to use modified Schrödinger ...

  20. Physical distributions of radon decay chain activities in air

    International Nuclear Information System (INIS)

    Rolle, R.

    2004-01-01

    The distribution of short-lived radon decay chain activities in air - in time, space and on aerosols - determines their exposure potential and measurement thereof. The radioactive decay constants and flow variables in a flow system combine, yielding activity concentration distributions and ratios of concentrations characteristic of the flow scheme, its source(s) and sink(s). The clock of 'internal' decay constants allows the unraveling of characteristics of the flow scheme from activity concentration measurements of individual members of a decay chain. Basic flow string calculations are shown. These can be assembled to define or simulate concentrations in a single- or multiple-compartment flow network. Response calculations to single- and multiple-step, or continuous changes in sources and sinks yield time-, spatial- and attachment-distributions. For the short-lived 222 Rn and 212 Pb decay chains the decay constants of the shorter-lived progeny in relation to the parent impose air activity ratios on successive chain members. Ratio limits had been used in the past to improve older grab-sampling- or integral gross-alpha measurement procedures for assessing exposure level. Assessment of individual concentrations, ratios and their distributions enables unravelling of dynamic flow systems, with restriction from the range of the parameters of flow and decay. An activity measuring instrument by itself represents a flow system with a response time distribution. Instrument response correction during continuous or quasi-continuous sampling and continuous spectrometric measurement allows far more accurate time-resolved measurement evaluation of continuously varying air concentrations, than previously attainable. Strong diurnal or even shorter (≤ 1 hr) changes probably are the norm in indoor and outdoor air activity concentrations. A mere average response evaluation, as used in steady state instrument calibration, and using less efficient instruments, is usually inadequate

  1. [beta]-delayed [alpha] decay of [sup 17]N

    Energy Technology Data Exchange (ETDEWEB)

    Dombsky, M.; Buchmann, L.; D' Auria, J.M.; Giesen, U.; Jackson, K.P.; King, J.D.; Korkmaz, E.; Korteling, R.G.; McNeely, P.; Powell, J.; Roy, G.; Trinczek, M.; Vincent, J. (Simon Fraser University, Burnaby, British Columbia, V5A 1S6 (Canada) University of Alberta, Edmonton, Alberta, T6G 2J1 (Canada) TRIUMF, Vancouver, British Columbia, V6T 2A3 (Canada) University of Toronto, Toronto, Ontario, M5S 1A7 (Canada))

    1994-04-01

    The [beta]-delayed [alpha] spectrum of [sup 17]N has been measured using a molecular [sup 17]NO[sup +] beam from the TRIUMF isotope separator. Thin surface barrier detector pairs were used to count the [alpha] particles in coincidence with [sup 13]C recoil nuclei. The resulting spectrum has been fitted with a [ital K]-matrix parametrization. The [beta]-delayed [alpha] decay of states at 7.99 and 8.20 MeV in the [sup 17]O daughter has been observed. A total [beta][alpha]-branching ratio of (2.5[plus minus]0.4)[times]10[sup [minus]5] has been determined for this decay mode of [sup 17]N.

  2. Effective liquid drop description for alpha decay of atomic nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Tavares, O.A.P.; Duarte, S.B. [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil); Rodriguez, O.; Guzman, F. [Instituto Superior de Ciencia y Tecnologia Nuclear (ISCTN), La Habana (Cuba); Goncalves, M. [Instituto de Radioprotecao e Dosimetria (IRD), Rio de Janeiro, RJ (Brazil); Garcia, F. [Sao Paulo Univ., SP (Brazil). Inst. de Fisica

    1998-06-01

    Alpha decay half-lives are presented in the framework of an effective liquid drop model for different combination of mass transfer descriptions and inertia coefficients. Calculated half-life-values for ground-state to ground-state favoured alpha transitions are compared with available, updated experimental data. Results have shown that the present model is very suitable to treat the alpha decay process on equal foot as cluster radioactivity and cold fission processes. Better agreement with the data is found when the sub-set of even-even alpha emitters are considered in the calculation. (author) 44 refs., 5 figs., 3 tabs.; e-mail: telo at ird.gov.br

  3. Modeling Radionuclide Decay Chain Migration Using HYDROGEOCHEM

    Science.gov (United States)

    Lin, T. C.; Tsai, C. H.; Lai, K. H.; Chen, J. S.

    2014-12-01

    Nuclear technology has been employed for energy production for several decades. Although people receive many benefits from nuclear energy, there are inevitably environmental pollutions as well as human health threats posed by the radioactive materials releases from nuclear waste disposed in geological repositories or accidental releases of radionuclides from nuclear facilities. Theoretical studies have been undertaken to understand the transport of radionuclides in subsurface environments because that the radionuclide transport in groundwater is one of the main pathway in exposure scenarios for the intake of radionuclides. The radionuclide transport in groundwater can be predicted using analytical solution as well as numerical models. In this study, we simulate the transport of the radionuclide decay chain using HYDROGEOCHEM. The simulated results are verified against the analytical solution available in the literature. Excellent agreements between the numerical simulation and the analytical are observed for a wide spectrum of concentration. HYDROGECHEM is a useful tool assessing the ecological and environmental impact of the accidental radionuclide releases such as the Fukushima nuclear disaster where multiple radionuclides leaked through the reactor, subsequently contaminating the local groundwater and ocean seawater in the vicinity of the nuclear plant.

  4. Competition between spontaneous fission ternary fission cluster decay and alpha decay in the super heavy nuclei of Z = 126

    Science.gov (United States)

    Manjunatha, H. C.; Sowmya, N.

    2018-01-01

    Super heavy nuclei may decay through the different decay modes such as spontaneous fission, ternary fission and cluster decay. There is a need to study the different decay modes such as spontaneous fission, ternary fission and cluster decay of super heavy nuclei. We studied the spontaneous fission, ternary fission and cluster decay of predicted isotopes of super heavy nuclei for Z = 126 and compared with that of alpha decay. This enables to study the competition between spontaneous fission, ternary fission, cluster decay and alpha decay in the super heavy nuclei of Z = 126. The comparison of half lives for different decay modes reveals that alpha decay is having smaller half lives than the other studied decay modes. A detailed study of branching ratio of alpha decay with respect to other decay modes also confirms that alpha decay is most dominant decay mode for the super heavy nuclei 318126, 319126, 320126 and 323-326126 and hence these nuclei can be detected through the alpha decay mode only.

  5. β-decay properties in the Cs decay chain

    Science.gov (United States)

    Benzoni, G.; Lică, R.; Borge, M. J. G.; Fraile, L. M.; IDS collaboration

    2018-02-01

    The study of the decay of neutron-rich Cs isotopes has two main objectives: on one side β decay is a perfect tool to access the low-spin structures in the daughter Ba nuclei, where the evolution of octupole deformed shapes can be followed, while, on the other hand, the study of the gross properties of these decays, in terms of decay rates and branching to delayed-neutron emission, are fundamental inputs for the modelling of the r-process in the Rare-Earth Elements peak. Results obtained at CERN-ISOLDE are discussed within this framework and compared to existing data and predictions from state-of-the-art nuclear models.

  6. Alpha-decay damage in titanite

    International Nuclear Information System (INIS)

    Hawthorne, F.C.; Groat, L.A.; Raudsepp, M.; Ball, N.A.; Kimata, Mitsuyoshi; Spike, F.D.; Gaba, R.; Halden, N.M.; Lumpkin, G.R.; Ewing, R.C.; Greegor, R.B.; Lytle, F.W.; Ercit, T.S.; Rossman, G.R.; Wicks, F.J.; Ramik, R.A.; Sherriff, B.L.; Fleet, M.E.; McCammon, C.

    1991-01-01

    Titanite can incorporate minor amounts of radioactive impurity components (particularly U and Th) that affect the crystal structure by α- and β-decay events. The authors have examined a series of chemically and structurally well-characterized titanite samples by a variety of techniques to follow the process of the metamictization process at low radiation doses. Ten titanite samples were characterized by electron microprobe analysis, powder X-ray diffraction, and powder infrared (IR) spectroscopy. The X-ray diffraction patterns vary from sharp and well resolved to almost totally degraded, reflecting the various degrees of α-decay damage. The powder IR spectra show a similar variation, and the order of increasing pattern degradation is almost the same as that for the order of increasing pattern degradation is almost the same as that for the X-ray diffraction patterns, indicating that both features reflect the same physical property of the material. However, the annealing behavior is different: powder X-ray diffraction patterns become sharp and well resolved; powder IR spectra sharpen slightly, but do not recover to anywhere near the same extent. High-temperature annealing only partly restores the structure, the apparent degree of recovery being dependent on the coherence length of the experimental technique used to characterize the material. The degree of recovery is also dependent on the and pattern of damage. The authors suggest that the original structure is recovered when the ratio of surface area to volume for the damaged material is high, and the interface can exert a strong memory effect on the amorphous material; when large equant aperiodic domains form, they are annealed to a more defect-free and relatively stable aperiodic network structure

  7. Alpha Decay of Even-Even Superheavy Nuclei

    International Nuclear Information System (INIS)

    Oudih, M.R.; Hamza, Y.; Fellah, M.; Allal, N.H.; Fellah, M.; Allal, N.H.

    2011-01-01

    Alpha decay properties of even-even superheavy nuclei with 112.Z.120 have been investigated using the Hartree-Fock-Bogoliubov approach. The method is based on the SkP Skyrme interaction and the Lipkin-Nogami prescription for treating the pairing correlations. The alpha decay energies are extracted from the binding energies and then used for the calculation of the decay half-lives using a formula similar to that of Viola-Seaborg. The parameters of the formula were obtained through a least square fit to even-even heavy nuclei taken from the tables of Audi- Wapstra and some more recent references. The results are compared with other theoretical evaluations.

  8. Alpha-particle and electron capture decay of 209Po

    International Nuclear Information System (INIS)

    Schima, F.J.; Colle, R.

    1996-01-01

    Gamma-ray and Kα X-ray emissions have been measured from a very pure 209 Po source containing less than 0.13% 208 Po activity and no detectable 210 Po (≤2 x 10 -4 %). The alpha-particle emission rate for this source has previously been determined. Data are presented that confirm alpha decay to the 205 Pb excited level at 262.8 keV, with an alpha-particle emission probability (±standard uncertainty) of 0.00559±0.00008. The ratio of K-shell electron capture to total electron capture for the second forbidden unique electron capture decay to the 896.6 keV level in 209 Bi was determined to be 0.594±0.018. The electron capture decay fraction was found to be 0.00454±0.00007, while the probabilities per decay for the 896.6, 262.8, and 260.5 keV gamma rays and the Bi Kα and Pb Kα X-rays were measured as 0.00445±0.00007, 0.00085±0.00002, 0.00254±0.00003, 0.00202±0.00005, and 0.00136±0.00005, respectively. (orig.)

  9. Soliton decay in a Toda chain caused by dissipation

    NARCIS (Netherlands)

    Brinkman, G.J.; Valkering, T.P.

    1990-01-01

    Consider a Toda chain with uniform friction. Starting with an initial condition that represents a soliton, we investigate its decay. The main result is that the solitary character is almost completely preserved. During the decay the wave activates other nonlinear modes. The corresponding actions

  10. Alpha decay properties of heavy and superheavy elements

    Indian Academy of Sciences (India)

    Abstract. Analysing accurately the lifetimes of α-decay chains is an important tool to detect and study the properties of superheavy nuclei. 48Ca is used in the synthesis of superheavy nuclei Z = 106−118 at Dubna. The experimental work of 48Ca projectiles at Dubna has given an opportunity to study the superheavy element ...

  11. Angular correlation measurements for 4-{alpha} decaying states in {sup 16}O

    Energy Technology Data Exchange (ETDEWEB)

    Wuosmaa, A.H.; Back, B.B.; Betts, R.R. [and others

    1995-08-01

    Previous measurements of the {sup 12}C({sup 12}C,{sup 8}Be){sup 16}O{sup *}(4 {alpha}) reaction identified discrete levels in {sup 16}O which decay by breakup into 4 {alpha} particles through a number of different decay sequences, including {sup 16}O{sup *} {yields} {sup 8}Be + {sup 8}Be and {alpha} + {sup 12}C (O{sub 2}{sup +}). These states are observed in a range of excitation energies where resonances are observed in inelastic {alpha} + {sup 12}C scattering leading to the {sup 8}Be + {sup 8}Be and {alpha} + {sup 12}C final states. These resonances were associated with 4 {alpha}-particle chain configurations in {sup 16}O. Should the states populated in the {sup 12}C + {sup 12}C reaction possess this same extended structure, it would serve as an important piece of evidence supporting the idea that even more deformed structures are formed in the {sup 24}Mg compound system. In order to more firmly make this association, it is important to determine the spins of the states populated in the {sup 12}C + {sup 12}C reaction.

  12. {alpha} decay of {sup 273}110: Shell closure at {ital N}=162

    Energy Technology Data Exchange (ETDEWEB)

    Lazarev, Y.A.; Lobanov, Y.V.; Oganessian, Y.T.; Utyonkov, V.K.; Abdullin, F.S.; Polyakov, A.N.; Rigol, J.; Shirokovsky, I.V.; Tsyganov, Y.S.; Iliev, S.; Subbotin, V.G.; Sukhov, A.M.; Buklanov, G.V.; Gikal, B.N.; Kutner, V.B.; Mezentsev, A.N.; Subotic, K. [Joint Institute for Nuclear Research, 141980 Dubna (Russian Federation); Wild, J.F.; Lougheed, R.W.; Moody, K.J. [University of California, Lawrence Livermore National Laboratory, Livermore, California 94551 (United States)

    1996-08-01

    In bombardments of {sup 244}Pu with {sup 34}S we discovered the {alpha}-decaying nuclide {sup 273}110. We conducted an extensive off-line search of the raw data for event sequences which fit the expected pattern of implantation in a position-sensitive detector and subsequent decay of {sup 273}110 and its descendants. We observed one three-member sequence of genetically linked {alpha} decays, resulting in {ital E}{sub {alpha}}=11.35 MeV, a half-life of 0.3{sub {minus}0.2}{sup +1.3} ms, and a production cross section of about 0.4 pb for {sup 273}110. Other possible {sup 273}110 event chains were also observed. The measured {alpha}-particle energy for the {ital N}=163 nuclide {sup 273}110 provides direct evidence for a neutron shell closure at {ital N}=162. {copyright} {ital 1996 The American Physical Society.}

  13. Alpha decay properties of superheavy nuclei Z = 126

    Science.gov (United States)

    Manjunatha, H. C.

    2016-01-01

    We have studied the possible isotopes of superheavy nuclei Z = 126 in the range 288 ≤ A ≥ 339 by studying through their α-decay properties. α-Decay half-life for the isotopes of Z = 126 superheavy nuclei in the range 288 ≤ A ≥ 339 is performed within the Coulomb and proximity potential model for deformed nuclei (CPPMDN). The calculated α half-lives agree with the values computed using the Viola-Seaborg systematic, the universal curve of Poenaru et al. (2011) [61]; (2012) [62] and the analytical formulas of Royer (2000) [63]. To identify the mode of decay of these isotopes, the spontaneous-fission half-lives were also evaluated using the semiempirical relation given by Xu et al. (2008) [72]. As we could observe α chains consistently from the nuclei 288-306126, we have predicted that these nuclei could not be synthesized and detected experimentally via α decay as their decay half-lives are too small, which span the order 10-9 to 10-6 s. Most of the predicted, unknown nuclei in the range 307 ≤ A ≥ 326 were found to have relatively long half-lives. Of these the nuclei 307126, 318126, 319126, 320126 and 323-326126 were found to have long half-lives and hence could be sufficient to detect them if synthesized in a laboratory.

  14. α -decay chains of superheavy Mt-279265 isotopes

    Science.gov (United States)

    Santhosh, K. P.; Nithya, C.

    2017-10-01

    The α -decay chains of the isotopes Mt-279265 are predicted by comparing the α half-lives calculated within the Coulomb and proximity potential model for deformed nuclei of Santhosh et al. [Nucl. Phys. A 850, 34 (2011)], 10.1016/j.nuclphysa.2010.12.002 with the spontaneous fission half-lives using the shell-effect-dependent formula of Santhosh and Nithya [Phys. Rev. C 94, 054621 (2016)], 10.1103/PhysRevC.94.054621. α half-lives also are calculated using different theoretical formalisms for comparison. The predicted half-lives and decay modes match well with the experimental results. The use of four different mass tables for calculating the α - decay energies indicates that the mass table of Wang et al. [Chin. Phys. C 41, 030003 (2017)], 10.1088/1674-1137/41/3/030003, which is based on the AME2016 atomic mass evaluation, is in better agreement with experimental results. The paper predicts long α chains from 265,267-269,271-273MT with half-lives within experimental limits. The isotopes 274-276,278Mt exhibit 2α chains followed by spontaneous fission. The 2α chain of 266Mt and the 4α chain of 270Mt end with electron capture. The isotopes Mt,279277 decay via spontaneous fission. We hope that the paper will open up new areas in this field.

  15. Alpha-decay energies of superheavy nuclei for the Fayans functional

    Energy Technology Data Exchange (ETDEWEB)

    Tolokonnikov, S.V. [National Research Centre ' ' Kurchatov Institute' ' , Moscow (Russian Federation); Moscow Institute of Physics and Technology, Dolgoprudny (Russian Federation); Borzov, I.N. [National Research Centre ' ' Kurchatov Institute' ' , Moscow (Russian Federation); Joint Institute for Nuclear Research, Dubna (Russian Federation); Kortelainen, M. [University of Jyvaskyla, Department of Physics, P.O. Box 35 (YFL), Jyvaskyla (Finland); University of Helsinki, Helsinki Institute of Physics, P.O. Box 64, Helsinki (Finland); Lutostansky, Yu.S. [National Research Centre ' ' Kurchatov Institute' ' , Moscow (Russian Federation); Saperstein, E.E. [National Research Centre ' ' Kurchatov Institute' ' , Moscow (Russian Federation); National Research Nuclear University MEPhI, Moscow (Russian Federation)

    2017-02-15

    Alpha-decay energies for several chains of superheavy nuclei are calculated within the self-consistent mean-field approach by using the Fayans functional FaNDF{sup 0}. They are compared to the experimental data and predictions of two Skyrme functionals, SLy4 and SkM{sup *}, and of the macro-micro method as well. The corresponding lifetimes are calculated with the use of the semi-phenomenological formulas by Parkhomenko and Sobiczewski and by Royer and Zhang. (orig.)

  16. α -decay chains of the superheavy nuclei Rg-350255

    Science.gov (United States)

    Santhosh, K. P.; Nithya, C.

    2017-05-01

    The decay modes and half-lives of 96 isotopes of the superheavy element roentgenium (Rg) within the range of 255 ≤A ≤350 come under investigation in the present paper. The isotopes which lie beyond the proton drip line are identified by calculating the one-proton and two-proton separation energies. The α -decay half-lives are calculated using the Coulomb and proximity potential model for deformed nuclei (CPPMDN). For a theoretical comparison the α half-lives are also evaluated using the Viola-Seaborg semiempirical relation, the universal curve of Poenaru et al., the analytical formula of Royer, and the universal decay law of Qi et al. Spontaneous fission half-lives are computed with the shell-effect-dependent formula of Santhosh and Nithya and the semiempirical formula of Xu et al. The decay modes are predicted by comparing the α -decay half-lives within the CPPMDN with the corresponding spontaneous fission half-lives computed by the shell-effect-dependent formula of Santhosh and Nithya. In our paper it is seen that the isotopes 255-271,273Rg lie beyond the proton drip line and hence decay through proton emission. The isotopes 272,274-277Rg exhibit long α chains. Three α chains are predicted from the isotopes Rg-282278. The isotopes Rg-345283 decay through spontaneous fission. The isotopes Rg-350346 are found to be stable against α decay. The theoretical results are compared with the available experimental results and are seen to be matching well. We hope that our predictions will be useful in future experimental investigations.

  17. Effect of including decay chains on predictions of equilibrium-type terrestrial food chain models

    International Nuclear Information System (INIS)

    Kirchner, G.

    1990-01-01

    Equilibrium-type food chain models are commonly used for assessing the radiological impact to man from environmental releases of radionuclides. Usually these do not take into account build-up of radioactive decay products during environmental transport. This may be a potential source of underprediction. For estimating consequences of this simplification, the equations of an internationally recognised terrestrial food chain model have been extended to include decay chains of variable length. Example calculations show that for releases from light water reactors as expected both during routine operation and in the case of severe accidents, the build-up of decay products during environmental transport is generally of minor importance. However, a considerable number of radionuclides of potential radiological significance have been identified which show marked contributions of decay products to calculated contamination of human food and resulting radiation dose rates. (author)

  18. CD8 beta chain influences CD8 alpha chain-associated Lck kinase activity

    OpenAIRE

    1995-01-01

    The CD8 molecule plays an important role in the differentiation of CD8+ T cells in the thymus and in their normal function in the periphery. CD8 exists on the cell surface in two forms, the alpha alpha homodimer and the alpha beta heterodimer. Recent studies indicate an important role for the CD8 beta chain in thymic development of CD8+ T cells and suggest that signaling via CD8 alpha beta may be distinct from CD8 alpha alpha. To better understand these differences, we introduced the CD8 beta...

  19. Alpha-decay fine structure versus electromagnetic transitions

    International Nuclear Information System (INIS)

    Peltonen, S.

    2003-01-01

    Alpha decay of even-even Rn isotopes is studied microscopically along the lines of Phys. Rev. C 64, 302 (2001). The results are compared against experimental fine-structure hindrance factors (HFs). We consider problems related to reproducing observed HFs with nuclear models, especially in case of the collective 2 + - excitations. We use the QRPA model with isovector SDI interaction in order to systematically evaluate theoretical HFs. Pairing gaps and the experimental energy of the 2 + - state fix all interaction parameters except the ratio between the isovector and isoscalar interaction strengths that is used as an additional free parameter of the model. Correlation between the electromagnetic E2-strength and HFs is observed, depending both on the isotope and the excitation energy. The choice of the single particle basis appears to affect strongly the theoretical HFs. Further and even more systematical studies are required in order explain this behaviour. (author)

  20. Triplication of alpha-globin genes is responsible for unusual alpha 113Leu/alpha 113His-globin chain ratios in sheep.

    Science.gov (United States)

    Vestri, R; Masina, P; Rando, A; Testa, A; Di Gregorio, P

    1987-10-01

    By investigations at the DNA and protein level, it has been shown that in sheep a previously detected, presumed quantitative allele of the II alpha 113His gene, displaying a reduced efficiency (called the II alpha 113His decreases gene), is carried by a chromosome bearing three alpha-globin loci. In particular, five sheep having an alpha 113Leu/alpha 113His-chain ratio of about 13:1 (13:1 phenotype) possessed the -I alpha 113Leu-II alpha 113Leu-/-I alpha 113Leu-II alpha 113Leu-III alpha 113His decreases genotype. One sheep showing a alpha 113Leu/alpha 113His-chain ratio of about 3:1 (3:1 phenotype) had the -I alpha 113Leu-II alpha 113His-/-I alpha 113Leu-II alpha 113Leu-III alpha 113His decreases genotype, while one sheep having a chain ratio of about 6:1 (6:1 phenotype) carried the -I alpha 113Leu-II alpha 113Leu-II alpha 113His decreases-/-I alpha 113Leu-II alpha 113Leu-III alpha 113His decreases genotype. Nineteen sheep, displaying the common phenotypes, all possessed the alpha alpha/alpha alpha gene arrangement. Furthermore, the possible location of the gene with reduced efficiency and the expression of the three genes in the triple alpha-globin loci chromosome are discussed.

  1. Algebraic decay in self-similar Markov chains

    International Nuclear Information System (INIS)

    Hanson, J.D.; Cary, J.R.; Meiss, J.D.

    1984-10-01

    A continuous time Markov chain is used to model motion in the neighborhood of a critical noble invariant circle in an area-preserving map. States in the infinite chain represent successive rational approximants to the frequency of the invariant circle. The nonlinear integral equation for the first passage time distribution is solved exactly. The asymptotic distribution is a power law times a function periodic in the logarithm of the time. For parameters relevant to Hamiltonian systems the decay proceeds as t -4 05

  2. INTRUDER STATES IN THE LEAD REGION, STUDIED BY ALPHA-DECAY

    NARCIS (Netherlands)

    WAUTERS, J; DENDOOVEN, P; HUYSE, M; REUSEN, G; VANDUPPEN, P; LIEVENS, P; KIRCHNER, R; KLEPPER, O; ROECKL, E; Neugart, R; Wohr, A

    1993-01-01

    The alpha decay of nuclei around the Z=82 closed proton shell is a powerful tool for the study of shape coexistence and intruder states in the lead region. Systematic measurements of alpha-decay properties of even-even mercury, lead, polonium and radon nuclei have been performed. From the deduced

  3. Intestinal Coccidiosis in a Patient with Alpha-chain Disease

    Science.gov (United States)

    Henry, Kristin; Bird, R. G.; Doe, W. F.

    1974-01-01

    During an ultrastructural study of small-intestinal mucosa from a patient suffering from alpha-chain disease organisms were identified within the epithelial cytoplasm which showed the fine structural features of the coccidian group. Though coccidiosis is well recognized as causing a diarrhoeal and often lethal illness in animals it has been neglected as a cause of disease in man. Thus this finding may be significant and warrants further investigation into its possible role in the pathogenesis of alpha-chain disease. ImagesFIG. 1FIG. 2FIG. 3FIG. 4 PMID:4131643

  4. Estimation of the alpha decay of Platinum isotopes using different versions of theoretical formula

    Science.gov (United States)

    Hosseini, S. S.; Hassanabadi, H.; Sobhani, H.

    The alpha decay half-lives of even-even and even-odd Platinum (Pt) nuclei have been studied within the Coulomb and proximity potential model (CPPM). The present study is restricted to even-even nuclei with A = 166-198. The results are compared with other calculations such as the Semi-empirical formula (SemFIS) from Poenaru et al. based on fission theory of alpha decay, the Viola-Seaborg (VS), Royer (R) and Brown formulae. Also, the alpha decay half-lives have been calculated using the Scaling law of Brown (SLB), the Universal Decay Law (UDL) of Qi et al., the Scaling Law of Horoi et al. (SLH), and Akrawy-Dorin formula (ADF) of Akrawy and Poenaru, which are the Royer modified formula for alpha decay half-live by adding asymmetry term.

  5. Spectroscopic Tools Applied to Element Z = 115 Decay Chains

    Directory of Open Access Journals (Sweden)

    Forsberg U.

    2014-03-01

    Full Text Available Nuclides that are considered to be isotopes of element Z = 115 were produced in the reaction 48Ca + 243Am at the GSI Helmholtzzentrum für Schwerionenforschung Darmstadt. The detector setup TASISpec was used. It was mounted behind the gas-filled separator TASCA. Thirty correlated α-decay chains were found, and the energies of the particles were determined with high precision. Two important spectroscopic aspects of the offline data analysis are discussed in detail: the handling of digitized preamplified signals from the silicon strip detectors, and the energy reconstruction of particles escaping to upstream detectors relying on pixel-by-pixel dead-layer thicknesses.

  6. Calculation of radioactive decay chains produced by neutron irradiation

    International Nuclear Information System (INIS)

    Ponti, C.

    1984-01-01

    The calculation of the decay chains of radioactive isotopes may be solved by different computer codes that apply similar numerical methods. Analytical forms of solution of this problem are known since a long time, but their implementation has always been hindered by the possible occurrence of large numerical errors or by the need, to avoid them, of very high numerical precision. In this paper the reason of these difficulties has been pointed out and solved. In particular a new family of mathematical identities has been found

  7. Synthesis and coupling reactions of alpha,alpha-dialkylated amino acids with nucleobase side chains.

    OpenAIRE

    Azumaya, I; Aebi, R; Kubik, S; Rebek, J

    1995-01-01

    Several di- and tripeptides containing protected purine (adenine) and pyrimidine (thymine) residues on their side chains were synthesized. The parent amino acids alpha, alpha-dialkylated in a symmetrical manner. An effective coupling procedure was developed for these sterically hindered amino acids: the fluoren-9-ylmethyloxycarbonyl-protected amino acid was dehydrated to its oxazolinone form, which was coupled in good yields with amino esters in hot tetrachloroethane.

  8. Spin correlations in decay chains involving W bosons TH1"-->

    Science.gov (United States)

    Smillie, J. M.

    2007-08-01

    We study the extent to which spin assignments of new particles produced at the LHC can be deduced in the decay of a scalar or fermion C into a new stable (or quasi-stable) particle A through the chain C→B±q, B±→AW±, W±→ℓ±νℓ where ℓ=e,μ. All possible spin assignments of the particles A and B are considered. Explicit invariant mass distributions of the quark and lepton are given for each set of spins, valid for all masses. We also construct the asymmetry between the chains with a W- and those with a W+. The Kullback Leibler distance between the distributions is then calculated to give a quantitative measure of our ability to distinguish the different spin assignments.

  9. Comparison of alpha decay and alpha transfer reactions in the lead region. [R matrix theory, absolute alpha widths, cross sections, 93 MeV

    Energy Technology Data Exchange (ETDEWEB)

    DeVries, R.M.

    1978-01-01

    Data were taken for five transitions in the lead region allowing a quantitative comparison with corresponding alpha-decay data via R-matrix theory using the same target + alpha nuclear potential. Good agreement between the absolute reduced widths determined from the two sets of data suggests that in transfer reactions, as in alpha decay, an alpha particle in its ground state is transferred in a one-step process. In a separate analysis, elastic and total reaction cross sections for the systems ..cap alpha.. + /sup 208/Pb, /sup 209/Bi were analyzed to obtain a limited set of potentials which, in turn, were used to calculate absolute alpha widths. Existing shell model calculations give ..gamma../sub ..cap alpha..//sup 2/ values three orders of magnitude smaller.

  10. Contributions to the study of heavy and superheavy nuclei stability in alpha-decay

    International Nuclear Information System (INIS)

    Silisteanu, I.

    1978-01-01

    Alpha-decay is treated in this work on the complete analogy of transfer reactions by means of nuclear shell models with continuous spectrum nucleons. Certain phenomenologically obtained or microscope evaluated data on low energy interactions between alpha-particles and nuclei, when related to nuclear structure data within the unified theory of nuclear reactions, allow of an improved accuracy in determining the alpha-particle wave function as well as of an estimation of alpha-probabilities in good keeping with experimental ones. The problem of alpha lifetimes thus narrows to the resolution of some homogeneous and inhomogeneous differential equations systems including the optic potential and the alpha formfactors. (author)

  11. Absolute measurement of the $\\beta\\alpha$ decay of $^{16}$N

    CERN Multimedia

    We propose to study the $\\beta$-decay of $^{16}$N at ISOLDE with the aim of determining the branching ratio for $\\beta\\alpha$ decay on an absolute scale. There are indications that the previously measured branching ratio is in error by an amount significantly larger than the quoted uncertainty. This limits the precision with which the S-factor of the astrophysically important $^{12}$C($\\alpha, \\gamma)^{16}$O reaction can be determined.

  12. Coupled channel alpha decay theory for even- and odd-mass light and heavy nuclei

    International Nuclear Information System (INIS)

    Rauscher, E.A.

    1978-02-01

    Four major approaches to the theoretical calculation of alpha decay widths were examined for light and heavy, even- and odd-mass nuclei. Application of the microscopic shell model rate theory as well as macroscopic models utilizing the coupled-channel formalism were studied. Use of the R-matrix and S-matrix theories have been applied in order to overcome problems involving dependency on the connection radius and nuclear potential parameters of the relative and absolute alpha decay widths. 105 references

  13. Cluster aspects of alpha decay of heavy spherical nuclei

    International Nuclear Information System (INIS)

    Kadmenskij, S.G.; Furman, V.I.; Kholan, S.; Khlebostroev, V.G.

    1975-01-01

    On the basis of the non-R-Matrix approach to the α-decay theory the surface α-cluster model of α-decay is introduced. In the frame of this model evidence is obtained about an important contribution of the peripherical region of parent nuclei for the absolute α-decay widths. A classification of the α-transitions following the values of experimental probabilities for the existence of α-particles at the nuclear surface is performed

  14. Decrease of alpha-chains in beta-thalassemia

    Directory of Open Access Journals (Sweden)

    M. Papadaki

    2013-03-01

    Full Text Available In the pathophysiology of beta-thalassemia, globin chain imbalance plays a central role in predicting red blood cell (RBC life span and disease severity. Strategies to improve globin chain imbalance are therefore a legitimate target in the management of this incurable genetic disorder. Classical gene addition with the available retroviral vectors can alter one of the two variables while combined reduction of achains could provide a more potent therapeutic effect. We developed foamy virus (FV vectors for the production of beta-globin and vectors targeting the a-globin transcript using the shRNA technology. Using FVderived vectors, we expressed human anti-a-globin short hairpin RNAs, off a potent PolIII promoter (H1; of the 4 different shRNAs tested, alpha-globin mRNA reduction varied from 6.3 to 54% of the control CD34+ cells. Similarly, vectors developed for the mouse alpha-globin, resulted in a significant reduction (range 15-28% of the control of aglobin in erythroid colonies of Lin- cells. To assay vector performance in vivo, we investigated the hematological parameters in thal3+/- mice transpalnted with FV-transduced Lin- cells, transduced with anti-alpha-globin shRNA. Despite low chimerism and low vector copy numbers (<0.5 per cell, we observed a 10% reduction in red cell distribution width, a marker for distorted erythropoiesis. We finally developed a combination FV vector expressing beta-globin off a HS40 enhancer and anti-alpha-globin shRNA and tested its performance in human CD34+ cells from a thalassemic patient. Globin chain imbalance was ameliorated from a beta/alpha ratio of 0.12 to the level of 0.5, clearly indicating a therapeutic benefit. Overall, shRNA control of alpha-globin excess is a feasible target but requires improvements since the RNAi effect is tough to predict and should ideally be combined with controllable elements.

  15. $\\alpha$-decay study of $^{182,184}$Tl

    CERN Document Server

    Van Beveren, C; Barzakh, A E; Cocolios, T E; de Groote, R P; Fedorov, D; Fedosseev, V N; Ferrer, R; Ghys, L; Huyse, M; Köster, U; Lane, J; Liberati, V; Lynch, K M; Marsh, B A; Molkanov, P L; Procter, T J; Rapisarda, E; Sandhu, K; Seliverstov, M D; Van Duppen, P; Venhart, M; Veselský, M

    2016-01-01

    α -decay spectroscopy of 182,184 Tl has been performed at the CERN isotope separator on-line ( ISOLDE ) facility. New fi ne-structure α decays have been observed for both isotopes. α -decay branching ratios of 0.089 ( 19 ) %, 0.047 ( 6 ) % and 1.22 ( 30 ) % have been deduced for the ( 10 − ) , ( 7 + ) and ( 2 − ) states respectively in 184 Tl and a lower limit of 0.49% for the α -decay branching ratio of 182 Tl. A new half-life of 9.5 ( 2 ) s for the ( 2 − ) state in 184 Tl and 1.9 ( 1 ) s for the low-spin state in 182 Tl has been deduced. Using α – γ coincidence analysis, multiple γ rays were observed de-exciting levels in 178,18 0 Au fed by 182,184 Tl α decays. The γ transitions connecting these low-lying states in 178,18 0 Au are essential to sort the data and possibly identify bands from in- beam studies in these isotopes. Owing to the complex fi ne-structure α decays and limited knowledge about the structure of the daughter nuclei, only partial level schemes could be constructed for bot...

  16. Force decay of elastomeric chains - a mechanical design and product comparison study.

    Science.gov (United States)

    Balhoff, David A; Shuldberg, Matthew; Hagan, Joseph L; Ballard, Richard W; Armbruster, Paul C

    2011-03-01

    To evaluate the percentage force decay of elastomeric chain products utilizing three different design mechanisms simulating canine retraction; and to evaluate the percentage force decay of elastomeric chain products from four different companies. In vitro, laboratory study. LSUHSC Dental School, New Orleans, LA, USA. Closed (non-spaced), grey elastomeric chains from four companies were selected for the study. Three acrylic resin jigs were constructed to provide a framework for three simulated space closure mechanisms. The 6-5-3, the chain loop, and the 6-3 were the configuration mechanisms used in the study. An electronic force gauge was used to measure the percentage force decay associated with each elastomeric chain over 28 days at preselected times. There was a significant difference in the mean percentage force decay for the three different mechanisms (P mechanical design had the smallest mean percentage force decay. There was a significant difference in the mean percentage force decay for the different companies (P mechanisms, Ormco had the smallest percentage force decay while Unitek had the highest percentage force decay. The significant difference in the mean percentage force decay for the different mechanisms suggests that the 6-3 design is a more efficient means of closing extraction spaces utilizing elastomeric chains.

  17. Alpha-decay-induced fracturing in zircon - The transition from the crystalline to the metamict state

    Science.gov (United States)

    Chakoumakos, Bryan C.; Murakami, Takashi; Lumpkin, Gregory R.; Ewing, Rodney C.

    1987-01-01

    Zonation due to alpha-decay damage in a natural single crystal of zircon from Sri Lanka is discussed. The zones vary in thickness on a scale from one to hundreds of microns. The uranium and thorium concentrations vary from zone to zone such that the alpha decay dose is between 0.2 x 10 to the 16th and 0.8 x 10 to the 16th alpha-events per milligram. The transition from the crystalline to the aperiodic metamict state occurs over this dose range. At doses greater than 0.8 x 10 to the 16th alpha events/mg there is no evidence for long-range order. This type of damage will accumulate in actinide-bearing, ceramic nuclear waste forms. The systematic pattern of fractures would occur in crystalline phases that are zoned with respect to actinide radionuclides.

  18. Study of the excited levels of 233Pa by the 237Np alpha decay

    International Nuclear Information System (INIS)

    Gonzalez, J.; Gaeta, R.; Vano, E.; Los Arcos, J. M.

    1978-01-01

    The excited levels in 233 P a following the 237 N p alpha decay have been studied, by performing different experiences to complete available data and supply new information. Thus, two direct alpha spectrum measurement, one alpha-gamma bidimensional coincidence experiment, three gamma-gamma and gamma-X ray coincidences and some other measurements of the gamma spectrum, direct and coincident with alpha-particles have been made. These last experiences have allowed to obviate usual radiochemical separation methods, the 233 P a radioactive descendent interferences being eliminated by means of the coincidence technic. As a result, a primary decay scheme has been elaborated, including 15 new gamma transitions and two new levels, not observed in the most recent works. (Author) 60 refs

  19. Six HLA-D region alpha-chain genes on human chromosome 6: polymorphisms and associations of DC alpha-related sequences with DR types.

    OpenAIRE

    Spielman, R S; Lee, J; Bodmer, W F; Bodmer, J G; Trowsdale, J

    1984-01-01

    Analysis of cosmid clones containing genes related to the HLA-DR alpha chain calls for at least six HLA-D region alpha-chain coding sequences in man; namely, DR alpha, DC alpha, DX alpha (very closely related to DC alpha), SB alpha 1, SB alpha 2 (two closely linked genes on the same cosmid clones), and DZ alpha. The first four genes have been described previously. SB alpha 2 and DZ alpha are recently identified genes, characterized by their unique and, from a limited study, nonpolymorphic ban...

  20. Properties of Alpha Decay to Rotational Bands of Heavy Nuclei

    Science.gov (United States)

    Wang, Y. Z.; Gu, J. Z.; Dong, J. M.; Peng, B. B.

    In the framework of the generalized liquid drop model (GLDM) and improved Royer's formula, we investigate the branching ratios and half-lives of α-decay to the members of the ground-state rotational bands of heavy even-even Fm and No isotopes. The calculated results are in good agreement with the available experimental data and some useful predictions are provided for future experiments.

  1. Gene encoding the human. beta. -hexosaminidase. beta. chain: Extensive homology of intron placement in the. alpha. - and. beta. -chain genes

    Energy Technology Data Exchange (ETDEWEB)

    Proia, R.L. (National Institute of Diabetes, Digestive and Kidney Diseases, Bethesda, MD (USA))

    1988-03-01

    Lysosomal {beta}-hexosaminidase is composed of two structurally similar chains, {alpha} and {beta}, that are the products of different genes. Mutations in either gene causing {beta}-hexosaminidase deficiency result in the lysosomal storage disease GM2-gangliosidosis. To enable the investigation of the molecular lesions in this disorder and to study the evolutionary relationship between the {alpha} and {beta} chains, the {beta}-chain gene was isolated, and its organization was characterized. The {beta}-chain coding region is divided into 14 exons distributed over {approx}40 kilobases of DNA. Comparison with the {alpha}-chain gene revealed that 12 of the 13 introns interrupt the coding regions at homologous positions. This extensive sharing of intron placement demonstrates that the {alpha} and {beta} chains evolved by way of the duplication of a common ancestor.

  2. Bremsstrahlung emission probability in the {alpha} decay of {sup 210}Po

    Energy Technology Data Exchange (ETDEWEB)

    Boie, Hans-Hermann

    2009-06-03

    A high-statistics measurement of bremsstrahlung emitted in the {alpha} decay of {sup 210}Po has been performed. The measured differential emission probabilities, which could be followed up to {gamma}-energies of {proportional_to} 500 keV, allow for the first time for a serious test of various model calculations of the bremsstrahlung accompanied {alpha} decay. It is shown that corrections to the {alpha}-{gamma} angular correlation due to the interference between the electric dipole and quadrupole amplitudes and due to the relativistic character of the process have to be taken into account. With the experimentally derived angular correlation the measured energydifferential bremsstrahlung emission probabilities show excellent agreement with the fully quantum mechanical calculation. (orig.)

  3. Alpha decay and cluster decay of some neutron-rich actinide nuclei

    Indian Academy of Sciences (India)

    2017-02-09

    Feb 9, 2017 ... Abstract. Nuclei in the actinide region are good in exhibiting cluster radioactivity. In the present work, the half-lives of α-decay and heavy cluster emission from certain actinide nuclei have been calculated using cubic plus Yukawa plus exponential model (CYEM). Our model has a cubic potential for the ...

  4. Spontaneous fission Vs alpha decay of superheavy nuclei with reduced uncertainty of Qα

    International Nuclear Information System (INIS)

    Santhosh Kumar, S.; Victor Babu, A.; Preetha, P.

    2015-01-01

    In recent experiments, α-decay has been indispensable for the identification of new nuclides. Because the experimentalists have to evaluate the values of the α-decay half-lives, during the experimental design, it is quite important and necessary to investigate the α decay of SHN theoretically. Besides the role of shell effects in the stability of SHN, the α-decay or spontaneous fission(SF) took important role. SHN with atomic number beyond 110 predominantly undergo sequential α-decay and long α-decay chains usually terminate by the SF. In experiment the measurement is mainly α- decay Q values and half-lives, while the major goal of the theory is to predict the half-lives to serve the experimental design. Q-value, one of the crucial quantity for a quantitative prediction of decay half-life, affects strongly the calculation of the half-life due to the exponential law, i.e., α- decay rates exhibit an exponential dependence (Geigger-Nuttall) on emission energy. Therefore it is extremely important and necessary to obtain an accurate theoretical Q-value in a reliable half life prediction during the experimental design

  5. Influence of proton-skin thickness on the {{\\alpha }} decays of heavy nuclei

    Science.gov (United States)

    Seif, W. M.; Abdurrahman, A.

    2018-01-01

    We investigate the effect of proton-skin thickness on the α decay process. We consider 188 neutron-deficient nuclei belonging to the isotopic chains from Te (Z = 52) to Pb (Z = 82). The calculations of the half-life are carried out in the framework of the preformed cluster model, with the Wentzel-Kramers-Brillouin penetration probability and assault frequency. It is shown that the proton-skin thickness ({\\varDelta }{{p}}) of the daughter nucleus gives rise to a total α- daughter nucleus interaction potential of relatively wide deep internal pocket and a thinner Coulomb barrier of less height. This increases the penetration probability but decreases the assault frequency. The overall impact of the proton-skin thickness appears as a decrease in the decay half-life. The proton-skin thickness decreases the stability of the nucleus. The half-lives of the proton-skinned isotopes along the isotopic chain decrease exponentially with increasing the proton-skin thickness, whereas the {Q}α -value increases with {\\varDelta }{{p}}. α-decay manifests itself as the second favorite decay mode of neutron-deficient nuclei, next to the {β }+-decay and before proton-decay. It is indicated as main, competing, and minor decay mode, at 21%, 7%, and 57%, respectively, of the investigated nuclei.

  6. Effects of alpha-decay on spent fuel corrosion behaviour

    International Nuclear Information System (INIS)

    Wiss, T.; Rondinella, V.V.; Cobos, J.; Wegen, D.H.; Amme, M.; Ronchi, C.

    2004-01-01

    An overview of results in the area of spent fuel characterization as nuclear waste is presented. These studies are focused on primary aspects of spent fuel corrosion, by considering different fuel compositions and burn ups, as well as a wide set of environmental conditions. The key parameter is the storage time of the fuel e.g. in view of spent fuel retrieval or in view of its final disposal. To extrapolate data obtainable from a laboratory-acceptable timescale to those expected after storage periods of interest have elapsed (amounting in the extreme case to geological ages) is a tough challenge. Emphasis is put on key aspects of fuel corrosion related to fuel properties at a given age and environmental conditions expected in the repository: e.g. the fuel activity (radiolysis effects), the effects of helium build-up and of groundwater composition. A wide range of techniques, from traditional leaching experiments to advanced electrochemistry, and of materials, including spent fuel with different compositions/burnups and analogues like the so-called alpha-doped UO 2 , are employed for these studies. The results confirm the safety of European underground repository concepts. (authors)

  7. cDNA clone for the alpha-chain of human beta-hexosaminidase: deficiency of alpha-chain mRNA in Ashkenazi Tay-Sachs fibroblasts.

    Science.gov (United States)

    Myerowitz, R; Proia, R L

    1984-09-01

    We have isolated a cDNA clone containing sequences complementary to mRNA encoding the alpha-chain of the lysosomal enzyme beta-hexosaminidase. RNA from a human lung fibroblast strain, IMR90, was enriched for beta-hexosaminidase messenger by polysome immunoselection with antiserum against beta-hexosaminidase A. This preparation was used to construct cDNA recombinant plasmids by the Okayama-Berg vector primer procedure. After transformation of Escherichia coli, 385 ampicillin-resistant colonies were obtained, 44 of which contained inserts in the plasmid DNA. Differential hybridization, with cDNA probes prepared from polysomal RNA enriched or depleted for beta-hexosaminidase messenger, was used to screen the recombinant plasmids for sequences encoding beta-hexosaminidase. One clone, p beta H alpha-1, containing a cDNA insert of approximately equal to 240 base pairs, was identified in this manner. The plasmid hybrid-selected a messenger from placental RNA that programed a translation system to synthesize the alpha-chain of beta-hexosaminidase. p beta H alpha-1 hybridized to an mRNA of approximately equal to 1.9 kilobases in preparations enriched separately in messenger for the alpha-chain or for both alpha- and beta-chains (by polysome immunoselection with antiserum against isolated alpha-chain or against beta-hexosaminidase A, respectively). It did not hybridize to an RNA preparation enriched for messenger of beta-chain by immunoselection with antiserum against beta-hexosaminidase B. The 1.9-kilobase mRNA was observed in poly(A)+ RNA preparations from control fibroblasts and from fibroblasts of a Tay-Sachs patient that synthesize an altered alpha-chain; however, it was not seen in similar preparations from fibroblasts of four Ashkenazi Tay-Sachs patients.

  8. Spinon decay in the spin-1/2 Heisenberg chain with weak next nearest neighbour exchange

    International Nuclear Information System (INIS)

    Groha, Stefan; Essler, Fabian H L

    2017-01-01

    Integrable models support elementary excitations with infinite lifetimes. In the spin-1/2 Heisenberg chain these are known as spinons. We consider the stability of spinons when a weak integrability breaking perturbation is added to the Heisenberg chain in a magnetic field. We focus on the case where the perturbation is a next nearest neighbour exchange interaction. We calculate the spinon decay rate in leading order in perturbation theory using methods of integrability and identify the dominant decay channels. The decay rate is found to be small, which indicates that spinons remain well-defined excitations even though integrability is broken. (paper)

  9. Improved Measurement of the CKM Angle alpha Using B0 to rho+rho- Decays.

    Energy Technology Data Exchange (ETDEWEB)

    Aubert, B.

    2005-03-29

    We present results from an analysis of B{sup 0} ({bar B}{sup 0}) {yields} {rho}{sup +}{rho}{sup -} using 232 million {Upsilon}(4S) {yields} B{bar B} decays collected with the BABAR detector at the PEP-II asymmetric-energy B Factory at SLAC. We measure the longitudinal polarization fraction f{sub L} = 0.978 {+-} 0.014(stat){sub -0.029}{sup +0.021}(syst) and the CP-violating parameters S{sub L} = -0.33 {+-} 0.24(stat){sub -0.14}{sup +0.08}(syst) and C{sub L} = -0.03 {+-} 0.18(stat) {+-} 0.09(syst). Using an isospin analysis of B {yields} {rho}{rho} decays we determine the unitarity triangle {alpha}. The solution compatible with the Standard Model is {alpha} = (100 {+-} 13){sup o}.

  10. ALPHA - The long-term passive decay heat removal and aerosol retention program

    International Nuclear Information System (INIS)

    Guentay, S.; Varadi, G.; Dreier, J.

    1996-01-01

    The Paul Scherrer Institute initiated the major new experimental and analytical program ALPHA in 1990. The program is aimed at understanding the long-term decay heat removal and aerosol questions for the next generation of Passive Light Water Reactors. The ALPHA project currently includes four major items: the large-scale, integral system behaviour test facility PANDA, which will be used to examine multidimensional effects of the SBWR decay heat removal system; an investigation of the thermal hydraulics of natural convection and mixing in pools and large volumes (LINX); a separate-effects study of aerosols transport and deposition in plenum and tubes (AIDA); while finally, data from the PANDA facility and supporting separate effects tests will be used to develop and qualify models and provide validation of relevant system codes. The paper briefly reviews the above four topics and current status of the experimental facilities. (author). 3 refs, 12 figs

  11. Structure effects in the region of superheavy elements via the α-decay chain of 293118

    International Nuclear Information System (INIS)

    Gupta, Raj K; Kumar, Sushil; Kumar, Rajesh; Balasubramaniam, M; Scheid, W

    2002-01-01

    The α-decay chain of 293 118, first proposed in the Berkeley cold fusion experiment 208 Pb( 86 Kr, 1n) and now retracted, is calculated by using the preformed cluster model (PCM) of one of the authors (RKG). Also, the possible branchings of α-decays to heavier cluster decays of all the parents in this chain are calculated for the first time. The calculated Q-values, penetrabilities and preformation factors for α-decays suggest that the 285 114 nucleus with Z=114, N=171 is a magic nucleus, either due to the magicity of Z=114, or N=172 or both. The N=172 is proposed to be a magic number in certain relativistic mean-field calculations, but with Z 120. The calculated cluster decays point to new interesting possibilities of 14 C decay of the 281 112 parent, giving rise to a (reasonably) deformed Z=106, N=161, 267 106 daughter (N=162 being now established as the deformed magic shell) or to a doubly magic 48 Ca cluster emitted from any of the parent nucleus in the α-decay chain. Apparently, these are exciting new directions for future experiments

  12. Investigation of $\\alpha$-decay rates of $^{221}$Fr, $^{224}$Ra and $^{226}$Ra in different environments

    CERN Multimedia

    2007-01-01

    It has recently been suggested, and indicated experimentally, that $\\alpha$- decay half-lives are modified by solid state effects in the surrounding environment. We propose here to measure with high accuracy the $\\alpha$-decay half-life of $^{221}$Fr, $^{224}$Ra and $^{226}$Ra in insulators and metals. Furthermore we plan to investigate the temperature dependency of the half-life in these materials (room temperature, 4 K and 10 mK).

  13. α-decay chain and associated cluster emission from neutron deficient 237Cf nucleus

    International Nuclear Information System (INIS)

    Jain, Deepika; Sharma, Manoj K.

    2015-01-01

    We have studied the α-decay chain of 237 Cf nucleus, which has been observed in the 3n evaporation channel when the semi-magic projectile 36 S strikes on 204 Pbv nucleus. The calculations are carried out by using preformed cluster model (PCM), with choices of spherical and quadruple deformation with in cold optimum orientation approach. The calculated half-lives of α-decay chain find relatively in nice agreement with experimental data for the deformed fragmentation approach. Along with α emission, the possibility of heavier clusters is also worked out and corresponding half-lives are predicted. (author)

  14. A study of ultraviolet renormalon ambiguities in the determination of $\\alpha_{s}$ from $\\tau$ decay

    CERN Document Server

    Altarelli, Guido; Ridolfi, G; Nason, P; Ridolfi, G

    1995-01-01

    The divergent large-order behaviour of the perturbative series relevant for the determination of \\as from \\tau decay is controlled by the leading ultraviolet (UV) renormalon. Even in the absence of the first infrared (IR) renormalon, an ambiguity of order \\Lambda^2/m_\\tau^2 is introduced. We make a quantitative study of the practical implications of this ambiguity. We discuss the magnitude of UV renormalon corrections obtained in the large-N_f limit, which, although unrealistic, is nevertheless interesting to some extent. We then study a number of improved approximants for the perturbative series, based on a change of variable in the Borel representation, such as to displace the leading UV renormalon singularity at a larger distance from the origin than the first IR renormalon. The spread of the resulting values of \\as(m^2_\\tau) obtained by different approximants, at different renormalization scales, is exhibited as a measure of the underlying ambiguities. Finally, on the basis of mathematical models, we disc...

  15. DCHAIN: A user-friendly computer program for radioactive decay and reaction chain calculations

    International Nuclear Information System (INIS)

    East, L.V.

    1994-05-01

    A computer program for calculating the time-dependent daughter populations in radioactive decay and nuclear reaction chains is described. Chain members can have non-zero initial populations and be produced from the preceding chain member as the result of radioactive decay, a nuclear reaction, or both. As presently implemented, chains can contain up to 15 members. Program input can be supplied interactively or read from ASCII data files. Time units for half-lives, etc. can be specified during data entry. Input values are verified and can be modified if necessary, before used in calculations. Output results can be saved in ASCII files in a format suitable for including in reports or other documents. The calculational method, described in some detail, utilizes a generalized form of the Bateman equations. The program is written in the C language in conformance with current ANSI standards and can be used on multiple hardware platforms

  16. Shape coexistence and shell-model intruder states in the lead region studied by $\\alpha$ -decay

    CERN Multimedia

    2002-01-01

    % IS336 \\\\ \\\\ Low-lying 0$^+$ states in even-even nuclei near closed shells can be a manifestation of the coexistence of different shapes in the same nucleus. Deformed bandstructures built upon these 0$^+$ states, coexisting at low energy with the ground state band, have been observed in several regions of the nuclear chart, including the Z=82 region. Such structures have been found in the neutron-deficient even Pb nuclei and the mixing between intruder and normal states has been studied by the $\\alpha$- decay of $^{194, 196, 198}$Po towards the 0$^+$ excited and ground states in $^{190, 192, 194}$Pb using $\\alpha$-e-t coincidence events. It is expected that shape coexistence will occur in the light Po isotopes as well. Evidence for a deformed band at low excitation energy in $^{196, 198}$Po has been found in in-beam studies and the $\\alpha$-decay of $^{202}$Rn studied at ISOLDE revealed feeding to a 0$^+$~state at 816~keV in $^{198}$Po. \\\\ \\\\It is our intention to investigate the $^{194, 196}$Po nuclei with ...

  17. Selection of nuclide decay chains for use in the assessment of the radiological impact of geological repositories for radioactive waste

    International Nuclear Information System (INIS)

    Thorne, M.C.

    1982-12-01

    The criteria for selecting nuclide decay chains for use in the assessment of the radiological impact of geological repositories for radioactive waste are given. The reduced chains recommended for use with SYVAC are described. (author)

  18. Excess alpha chains are lost from beta-thalassemic reticulocytes by proteolysis

    International Nuclear Information System (INIS)

    Testa, U.; Hinard, N.; Beuzard, Y.; Tsapis, A.; Galacteros, F.; Thomopoulos, P.; Rosa, J.

    1981-01-01

    During incubation of reticulocytes from patients with beta-thalassemia, after labeling of the hemoglobin with radioactive amino acids, the excess alpha chains are gradually lost from the cells. The aim of this study was to investigate the mechanism of this phenomenon. A system was developed in which reticulocytes from beta-thalassemia patients are labeled with [3H]leucine, washed several times in nonradioactive medium, and then incubated in the same medium containing puromycin added in order to stop further protein synthesis. The results have clearly shown that excess alpha chains are gradually degraded by proteolysis. N-ethylmaleimide or epsilon-aminocaproic acid inhibited the proteolysis of free alpha chains. The addition of either ATP or hemin did not change the rate of alpha chain degradation. The time required to degrade 50% of the pool of free alpha chains was directly dependent on the initial value of this pool. This finding suggests the absence of a significant individual variation in the ability to proteolyse free alpha chains

  19. Polymorphic expression in the CD8alpha chain surface receptor of African lions (Panthera leo).

    Science.gov (United States)

    Bull, Marta E; Gebhard, Douglas G; Tompkins, Wayne A F; Kennedy-Stoskopf, Suzanne

    2002-01-15

    Free-ranging African lion (Panthera leo) peripheral blood mononuclear cells (PBMC) were examined using flow cytometry and antibodies developed for use in the domestic cat to determine if phenotypic changes occurred in lion lymphocytes as a result of feline immunodeficiency virus (FIV) infection. The percentage of CD8 cells from lion peripheral blood was considerably lower than in the domestic cat. Lions with elevated levels of CD8+ cells were typically infected with FIV, similar to observations in the domestic cat. Antibodies against the alpha chain of the CD8 receptor (monoclonal antibody (mAb) 3.357) did not react consistently in all lions examined. Flow cytometric analysis determined that approximately 82 and 80% of the animals from Kruger and Hluhluwe-Umfolozi National Parks in South Africa reacted with the monoclonal antibody against the alpha chain of CD8 receptor, while only 17% of the lions in Etosha National Park in Namibia cross-reacted with the CD8alpha chain. There was no apparent correlation between FIV status and CD8alpha chain reactivity. The relative isolation of Etosha from the other two parks could explain the marked difference in CD8alpha chain expression and suggests that lions similar to other mammalian species demonstrate polymorphic expression of the CD8alpha chain (197).

  20. Alternative splicing of T cell receptor (TCR) alpha chain transcripts containing V alpha 1 or V alpha 14 elements.

    Science.gov (United States)

    Mahotka, C; Hansen-Hagge, T E; Bartram, C R

    1995-10-01

    Human acute lymphoblastic leukemia cell lines represent valuable tools to investigate distinct steps of the complex regulatory pathways underlying T cell receptor recombination and expression. A case in point are V delta 2D delta 3 and subsequent V delta 2D delta 3J alpha rearrangements observed in human leukemic pre-B cells as well as in normal lymphopoiesis. The functional expression of these unusual (VD) delta (JC) alpha hybrids is almost exclusively prevented by alternative splicing events. In this report we show that alternative splicing at cryptic splice donor sites within V elements is not a unique feature of hybrid TCR delta/alpha transcripts. Among seven V alpha families analyzed by RT-PCR, alternatively spliced products were observed in TCR alpha recombinations containing V alpha 1 or V alpha 14 elements. In contrast to normal peripheral blood cells and thymocytes, the leukemia cell line JM expressing functional V alpha 1J alpha 3C alpha transcripts lacked evidence of aberrant TCR alpha RNA species.

  1. α decay chains from Z = 118 superheavy nuclei in the range 271 ≤A≤ 310

    Science.gov (United States)

    Santhosh, K. P.; Priyanka, B.

    2014-06-01

    An extensive investigation on the α decay properties of the isotopes of the superheavy nuclei with Z = 118, within the range 271 ≤A≤ 310, has been performed within the Coulomb and proximity potential model for deformed nuclei. The α decay half-lives of 118294 and its decay products, evaluated using our formalisms, are in good agreement with the experimental results. The calculated α half-lives were also found to be matching well with the values computed using the Viola-Seaborg systematic, the universal curve of Poenaru et al. [Phys. Rev. C 83, 014601 (2011), 10.1103/PhysRevC.83.014601;Phys. Rev. C 85, 034615 (2012), 10.1103/PhysRevC.85.034615] and the analytical formulas of Royer [J. Phys. G: Nucl. Part. Phys. 26, 1149 (2000), 10.1088/0954-3899/26/8/305]. So as to identify the mode of decay of these isotopes, the spontaneous-fission half-lives were also evaluated for all the isotopes under study and, our prediction of 3α chains from 118294 go hand in hand with the experimental observations. Our study also unveils that those isotopes of Z = 118 with A ≥ 301 and with A ≤ 275 do not survive fission, thus restricting the α decay within the range of 276 ≤A≤ 300, and we hope that the theoretical prediction of 5α decay chains consistently from 118289-293 isotopes provides a new perspective to experimentalists.

  2. A Brief Review of Ultra-Rare Alpha Decay Detection Technique

    CERN Document Server

    Tsyganov, Yu S

    2006-01-01

    Three approaches to the measurement of a rare alpha decaying products produced in heavy-ion induced nuclear reactions are described. One is based on a chemical extraction and following deposition of the nuclides under investigation onto the surface of the detector, whereas the second one is associated with long-lived products implanted into silicon detectors by using the electromagnetic separation technique. The third approach relates with an application of real-time mode detection of correlated energy-time-position recoil-alpha sequences from $^{48}$Ca-induced nuclear reactions with actinide targets, like $^{242, 244}$Pu, $^{245,248}$Cm, $^{243}$Am, and $^{249}$Cf. Namely with this technique it has became possible to provide a radical suppression of backgrounds in the full fusion (3-5$n$) reactions aimed at the synthesis of superheavy elements with Z=113-118.

  3. The human HLA class II alpha chain gene DZ alpha is distinct from genes in the DP, DQ and DR subregions.

    OpenAIRE

    Trowsdale, J; Kelly, A

    1985-01-01

    A new human HLA class II alpha gene DZ alpha was sequenced. The structure and organisation of the gene was similar to other alpha chain genes except for a particularly small intron (95 bp) after the exon encoding the alpha 2 domain, and the position of the stop codon, which was on a different exon to that encoding the cytoplasmic portion of the molecule. Comparison of the DZ alpha sequence with other class II genes showed that the gene is about as distantly related to alpha chain genes in the...

  4. Updated Measurement of the CKM Angle alpha Using B0->rho+rho- Decays

    Energy Technology Data Exchange (ETDEWEB)

    Aubert, B

    2006-09-26

    The authors present results from an analysis of B{sup 0} {yields} {rho}{sup +}{rho}{sup -} using 316 fb{sup -1} of {Upsilon}(4S) {yields} B{bar B} decays observed with the BABAR detector at the PEP-II asymmetric-energy B Factory at SLAC. They measure the B{sup 0} {yields} {rho}{sup +}{rho}{sup -} branching fraction, longitudinal polarization fraction f{sub L}, and the CP-violating parameters S{sub long} and C{sub long}: {Beta}(B{sup 0} {yields} {rho}{sup +}{rho}{sup -}) = (23.5 {+-} 2.2(stat) {+-} 4.1(syst)) x 10{sup -6}, f{sub L} = 0.977 {+-} 0.024(stat){sub -0.013}{sup +0.015}(syst), S{sub long} = -0.19 {+-} 0.21(stat){sub -0.07}{sup +0.05}(syst), C{sub long} = -0.07 {+-} 0.15(stat) {+-} 0.06(syst). Using an isospin analysis of B {yields} {rho}{rho} decays they determine the angle {alpha} of the unitarity triangle. One of the two solutions, {alpha} [74,117]{sup o} at 68% CL, is compatible with the standard model. All results presented here are preliminary.

  5. Swelling induced by alpha decay in monazite and zirconolite ceramics: A XRD and TEM comparative study

    Science.gov (United States)

    Deschanels, X.; Seydoux-Guillaume, A. M.; Magnin, V.; Mesbah, A.; Tribet, M.; Moloney, M. P.; Serruys, Y.; Peuget, S.

    2014-05-01

    Zirconolite and monazite matrices are potential ceramics for the containment of actinides (Np, Cm, Am, Pu) which are produced over the reprocessing of spent nuclear fuel. Actinides decay mainly through the emission of alpha particles, which in turn causes most ceramics to undergo structural and textural changes (amorphization and/or swelling). In order to study the effects of alpha decays on the above mentioned ceramics two parallel approaches were set up. The first involved the use of an external irradiation source, Au, which allowed the deposited recoil energy to be simulated. The second was based on short-lived actinide doping with 238Pu, (i.e. an internal source), via the incorporation of plutonium oxide into both the monazite and zirconolite structures during synthesis. In both types of irradiation experiments, the zirconolite samples became amorphous at room temperature with damage close to 0.3 dpa; corresponding to a critical dose of 4 × 1018 α g-1 (i.e. ∼1.3 × 1021 keV cm-3). Both zirconolite samples also showed the same degree of macroscopic swelling at saturation (∼6%), with ballistic processes being the predominant damaging effect. In the case of the monazite however, the macroscopic swelling and amorphization were dependent on the nature of the irradiation. Externally, (Au), irradiated samples became amorphous while also demonstrating a saturation swelling of up to 8%. In contrast to this, the swelling of the 238Pu doped samples was much smaller at ∼1%. Also, unlike the externally (Au) irradiated monazite these 238Pu doped samples remained crystalline up to 7.5 × 1018 α g-1 (0.8 dpa). XRD, TEM and swelling measurements were used to fully characterize and interpret this behavior. The low swelling and the conservation of the crystalline state of 238Pu doped monazite samples indicates that alpha annealing took place within this material.

  6. An improved method of lifetime measurement of nuclei in radioactive decay chain

    International Nuclear Information System (INIS)

    Puzović, J.M.; Manić, D.; Nađđerđ, L.J.

    2017-01-01

    We present an improved statistical method for the calculation of mean lifetime of nuclei in a decay chain with an uncertain relation between mother and daughter nuclei. The method is based on the formation of time distribution of intervals between mother and daughter nuclei, without trying to set the exact mother-daughter nuclei relationship. If there is a coincidence of mother and daughter nuclei decays, the sum of these distributions has flat term on which an exponential term is superimposed. Parameters of this exponential function allow lifetime of daughter nucleus to be extracted. The method is tested on Monte Carlo simulation data.

  7. A new scanning system for alpha decay events as calibration sources for range-energy relation in nuclear emulsion

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, J., E-mail: jyoshida@gifu-u.ac.jp; Kinbara, S.; Mishina, A.; Nakazawa, K.; Soe, M.K.; Theint, A.M.M.; Tint, K.T.

    2017-03-01

    A new scanning system named “Vertex picker” has been developed to rapid collect alpha decay events, which are calibration sources for the range-energy relation in nuclear emulsion. A computer-controlled optical microscope scans emulsion layers exhaustively, and a high-speed and high-resolution camera takes their micrographs. A dedicated image processing picks out vertex-like shapes. Practical operations of alpha decay search were demonstrated by emulsion sheets of the KEK-PS E373 experiment. Alpha decays of nearly 28 events were detected in eye-check work on a PC monitor per hour. This yield is nearly 20 times more effective than that by the conventional eye-scan method. The speed and quality is acceptable for the coming new experiment, J-PARC E07.

  8. A new scanning system for alpha decay events as calibration sources for range-energy relation in nuclear emulsion

    International Nuclear Information System (INIS)

    Yoshida, J.; Kinbara, S.; Mishina, A.; Nakazawa, K.; Soe, M.K.; Theint, A.M.M.; Tint, K.T.

    2017-01-01

    A new scanning system named “Vertex picker” has been developed to rapid collect alpha decay events, which are calibration sources for the range-energy relation in nuclear emulsion. A computer-controlled optical microscope scans emulsion layers exhaustively, and a high-speed and high-resolution camera takes their micrographs. A dedicated image processing picks out vertex-like shapes. Practical operations of alpha decay search were demonstrated by emulsion sheets of the KEK-PS E373 experiment. Alpha decays of nearly 28 events were detected in eye-check work on a PC monitor per hour. This yield is nearly 20 times more effective than that by the conventional eye-scan method. The speed and quality is acceptable for the coming new experiment, J-PARC E07.

  9. Renal Amyloidosis Associated With 5 Novel Variants in the Fibrinogen A Alpha Chain Protein.

    Science.gov (United States)

    Rowczenio, Dorota; Stensland, Maria; de Souza, Gustavo A; Strøm, Erik H; Gilbertson, Janet A; Taylor, Graham; Rendell, Nigel; Minogue, Shane; Efebera, Yvonne A; Lachmann, Helen J; Wechalekar, Ashutosh D; Hawkins, Philip N; Heimdal, Ketil R; Selvig, Kristian; Lægreid, Inger K; Demoulin, Nathalie; Aydin, Selda; Gillmore, Julian D; Wien, Tale N

    2017-05-01

    Fibrinogen A alpha chain amyloidosis is an autosomal dominant disease associated with mutations in the fibrinogen A alpha chain ( FGA ) gene, and it is the most common cause of hereditary renal amyloidosis in the UK. Patients typically present with kidney impairment and progress to end-stage renal disease over a median time of 4.6 years. Six patients presented with proteinuria, hypertension, and/or lower limb edema and underwent detailed clinical and laboratory investigations. A novel FGA gene mutation was identified in each case: 2 frameshift mutations F521Sfs*27 and G519Efs*30 and 4 single base substitutions G555F, E526K, E524K, R554H. In 5 subjects, extensive amyloid deposits were found solely within the glomeruli, which stained specifically with antibodies to fibrinogen A alpha chain, and in one of these cases, we found coexistent fibrinogen A alpha chain amyloidosis and anti-glomerular basement membrane antibody disease. One patient was diagnosed with light-chain amyloidosis after a bone marrow examination revealed a small clonal plasma cell population, and laser microdissection of the amyloid deposits followed by liquid chromatography and tandem mass spectrometry identified kappa light chain as the fibril protein. We report 6 novel mutations in the FGA gene: 5 were associated with renal fibrinogen A alpha chain amyloidosis and 1 was found to be incidental to light-chain amyloid deposits discovered in a patient with a plasma cell dyscrasia. Clinical awareness and suspicion of hereditary amyloidosis corroborated by genetic analysis and adequate typing using combined immunohistochemistry and laser microdissection and mass spectrometry is valuable to avoid misdiagnosis, especially when a family history of amyloidosis is absent.

  10. Analysis of decay chains of superheavy nuclei produced in the 249Bk+48Ca and 243Am+48Ca reactions

    International Nuclear Information System (INIS)

    Zlokazov, V B; Utyonkov, V K

    2017-01-01

    The analysis of decay chains starting at superheavy nuclei 293 Ts and 289 Mc is presented. The spectroscopic properties of nuclei identified during the experiments using the 249 Bk+ 48 Ca and 243 Am+ 48 Ca reactions studied at the gas-filled separators DGFRS, TASCA and BGS are considered. We present the analysis of decay data using widely adopted statistical methods and applying them to the short decay chains of parent odd- Z nuclei. We find out that the recently suggested method of analyzing decay chains by Forsberg et al may lead to questionable conclusions when applied for the analysis of radioactive decays. Our discussion demonstrates reasonable congruence of α -particle energies and decay times of nuclei assigned to isotopes 289 Mc, 285 Nh and 281 Rg observed in both reactions. (paper)

  11. Analysis of decay chains of superheavy nuclei produced in the 249Bk+48Ca and 243Am+48Ca reactions

    Science.gov (United States)

    Zlokazov, V. B.; Utyonkov, V. K.

    2017-07-01

    The analysis of decay chains starting at superheavy nuclei 293Ts and 289Mc is presented. The spectroscopic properties of nuclei identified during the experiments using the 249Bk+48Ca and 243Am+48Ca reactions studied at the gas-filled separators DGFRS, TASCA and BGS are considered. We present the analysis of decay data using widely adopted statistical methods and applying them to the short decay chains of parent odd-Z nuclei. We find out that the recently suggested method of analyzing decay chains by Forsberg et al may lead to questionable conclusions when applied for the analysis of radioactive decays. Our discussion demonstrates reasonable congruence of α-particle energies and decay times of nuclei assigned to isotopes 289Mc, 285Nh and 281Rg observed in both reactions.

  12. cDNA clone for the alpha-chain of human beta-hexosaminidase: deficiency of alpha-chain mRNA in Ashkenazi Tay-Sachs fibroblasts.

    OpenAIRE

    Myerowitz, R; Proia, R L

    1984-01-01

    We have isolated a cDNA clone containing sequences complementary to mRNA encoding the alpha-chain of the lysosomal enzyme beta-hexosaminidase. RNA from a human lung fibroblast strain, IMR90, was enriched for beta-hexosaminidase messenger by polysome immunoselection with antiserum against beta-hexosaminidase A. This preparation was used to construct cDNA recombinant plasmids by the Okayama-Berg vector primer procedure. After transformation of Escherichia coli, 385 ampicillin-resistant colonies...

  13. Alpha decay properties of the semi-magic nucleus 219Np

    Science.gov (United States)

    Yang, H. B.; Ma, L.; Zhang, Z. Y.; Yang, C. L.; Gan, Z. G.; Zhang, M. M.; Huang, M. H.; Yu, L.; Jiang, J.; Tian, Y. L.; Wang, Y. S.; Wang, J. G.; Liu, Z.; Liu, M. L.; Duan, L. M.; Zhou, S. G.; Ren, Z. Z.; Zhou, X. H.; Xu, H. S.; Xiao, G. Q.

    2018-02-01

    The semi-magic nucleus 219Np was produced in the fusion reaction 187Re(36Ar, 4n)219Np at the gas-filled recoil separator SHANS (Spectrometer for Heavy Atoms and Nuclear Structure). A fast electronics system based on waveform digitizers was used in the data acquisition and the sampled pulses were processed by digital algorithms. The reaction products were identified using spatial and time correlations between the implants and subsequent α decays. According to the observed α-decay chain, an energy of Eα = 9039 (40) keV and a half-life of T1/2 =0.15-0.07 + 0.72 ms were determined for 219Np. The deduced proton binding energy of 219Np fits well into the systematics, which gives another evidence of that there is no sub-shell closure at Z = 92. The influence of the N = 126 shell closure on the stability of Np isotopes is discussed within the framework of α-decay reduced widths.

  14. Evaluation of maximum radionuclide concentration from decay chains migration in aquifers

    International Nuclear Information System (INIS)

    Aquino Branco, O.E. de.

    1983-01-01

    The mathematical formulation of the mechanisms involved in the transport of contaminants in aquifers is presented. The methodology employed is described. A method of calculation the maximum concentration of radionuclides migrating in the underground water, and resulting from one decay chain, is then proposed. As an example, the methodology is applied to a waste basin, built to receive effluents from a hypothectical uranium ore mining and milling facility. (M.A.C.) [pt

  15. The effect of alcohol-containing mouthwash and alcohol-free mouthwash towards the power chains force decay

    Directory of Open Access Journals (Sweden)

    Willem Santana

    2017-11-01

    Full Text Available Introduction: Power chains is the common device used in fixed orthodontic treatment. Force decay in power chains is a problem that can affect the teeth movement due to a continuous force cannot be maintained. Force decay in power chain can be affected by the use of alcohol or non-alcohol mouthwash. The objective of this study was to determine the effect of alcoholic mouthwash, non-alcoholic mouthwash and artificial saliva towards the power chains force decay. Methods: This research was an experimental analytic laboratory in vitro with the comparative approach. The sample in this study were 40 power chain - short A (SA; 40 power chain - short B (SB; 40 power chain - long A (LA; and 40 power chain - long B (LB, which divided into 5 groups that were consecutively exposed to the artificial saliva as control group; Minosep® with 0.1% of chlorhexidine gluconate; Listerine® with 0% of alcohol; Hexadol® with 9% of alcohol; and Listerine® with 26.9% of alcohol. The measurement of force decay was performed with digital force gauge on day 0, 1, 14 and 28. The statistical analysis was done by using the Wilcoxon and Mann-Whitney tests. Result: There was a significant difference (p < 0.05 between the force decay of power chain that exposed to the alcoholic mouthwash, non-alcoholic mouthwash and the artificial saliva. Conclusion: The force decay level of power chain that exposed to an alcoholic mouthwash was higher compared to the force decay level of power chain that exposed to a non-alcoholic mouthwash and an artificial saliva.

  16. Gene encoding the human beta-hexosaminidase beta chain: extensive homology of intron placement in the alpha- and beta-chain genes.

    Science.gov (United States)

    Proia, R L

    1988-03-01

    Lysosomal beta-hexosaminidase (EC 3.2.1.52) is composed of two structurally similar chains, alpha and beta, that are the products of different genes. Mutations in either gene causing beta-hexosaminidase deficiency result in the lysosomal storage disease GM2-gangliosidosis. To enable the investigation of the molecular lesions in this disorder and to study the evolutionary relationship between the alpha and beta chains, the beta-chain gene was isolated, and its organization was characterized. The beta-chain coding region is divided into 14 exons distributed over approximately 40 kilobases of DNA. Comparison with the alpha-chain gene revealed that 12 of the 13 introns interrupt the coding regions at homologous positions. This extensive sharing of intron placement demonstrates that the alpha and beta chains evolved by way of the duplication of a common ancestor.

  17. Measurement of the decay rate and form factor parameter $\\alpha_{K}*$ in the decay $K_{L} \\rightarrow e^{+}e^{-}\\gamma$

    CERN Document Server

    Fanti, V; Musa, L; Marras, D; Nappi, A; Hay, B; Moore, R W; Moore, K N; Munday, D J; Needham, M D; Parker, M A; White, T O; Wotton, S A; Barr, Giles David; Bocquet, G; Bremer, J; Ceccucci, Augusto; Cundy, Donald C; Doble, Niels T; Funk, W; Gatignon, L; Gianoli, A; Gonidec, A; Govi, G; Grafström, P; Kubischta, Werner; Lacourt, A; Luitz, S; Kesseler, G; Matheys, J P; Norton, Alan Robert; Palestini, S; Panzer-Steindel, B; Schinzel, D; Taureg, Hans; Velasco, M; Vossnack, O; Wahl, H; Wirrer, G; Kekelidze, V D; Mestvirishvili, A; Potrebenikov, Yu K; Tatishvili, G T; Tkachev, A L; Zinchenko, A I; Boyle, O; Martin, V J; Knowles, I G; Parsons, H; Dalpiaz, Pietro; Duclos, J; Frabetti, P L; Martini, M; Petrucci, F; Porcu, M; Savrié, M; Bizzeti, A; Calvetti, M; Collazuol, G; Graziani, G; Iacopini, E; Lenti, M; Michetti, A; Becker, H G; Blümer, H; Buchholz, P; Coward, D H; Ebersberger, C; Fox, H; Kalter, A; Kleinknecht, K; Koch, U; Köpke, L; Renk, B; Scheidt, J; Schmidt, J; Schönharting, V; Schué, Yu; Wilhelm, R; Winhart, A; Wittgen, M; Chollet, J C; Crépé, S; Iconomidou-Fayard, L; Fayard, Louis; Ocariz, J; Unal, G; Vattolo, D; Wingerter-Seez, I; Anzivino, Giuseppina; Cenci, P; Lubrano, P; Pepé, M; Gorini, B; Calafiura, P; Carosi, R; Cerri, C; Cirilli, M; Costantini, F; Fantechi, R; Giudici, Sergio; Mannelli, I; Marzulli, V M; Pierazzini, G M; Sozzi, M; Chèze, J B; Cogan, J; De Beer, M; Debu, P; Formica, A; Granier de Cassagnac, R; Khristov, P Z; Mazzucato, E; Peyaud, B; Schanne, S; Turlay, René; Vallage, B; Augustin, I; Bender, M; Holder, M; Ziolkowski, M; Arcidiacono, R; Biino, C; Marchetto, F; Menichetti, E; Nassalski, J P; Rondio, Ewa; Szleper, M; Wislicki, W; Wronka, S; Dibon, Heinz; Fischer, G; Jeitler, Manfred; Markytan, Manfred; Mikulec, I; Neuhofer, Günther; Pernicka, Manfred; Taurok, Anton

    1999-01-01

    The decay rate of the neutral K meson $\\mathrm{K_{L} \\rightarrow e^{+}e^{-}\\gamma}$ has been measured with the NA48 detector at the CERN SPS. A total of 6864 events has been observed with an estimated background of 10 events. The branching ratio is $\\mathrm{\\Gamma(K_{L} \\rightarrow e^{+}e^{-}\\gamma)/\\Gamma(K_{L} rightarrow all) = (1.06 \\pm 0.02_{stat.} \\pm 0.02_{sys.} \\pm 0.04_{calc.})\\times 10^{-5}}$. The parameter describing the relative strength of the two contributing amplitudes to this decay through $\\mathrm{\\alpha_{K^{*}}}$ intermediate seudoscalar or vector mesons, was measured to be $\\mathrm{\\alpha_{K^{*}} = -0.36 \\pm 0.06_{stat.} \\pm 0.02_{sys.}}$

  18. Transport of radioactive decay chains in finite and semi-infinite porous media

    International Nuclear Information System (INIS)

    Lung, H.C.; Chambre, P.L.; Pigford, T.H.; Lee, W.W.L.

    1987-09-01

    This report presents analytic solutions, numerical implementation and numerical illustrations for the transport of radioactive decay chains of arbitary length in porous media of limited and unlimited extent. The analytic solutions for the problem of chains transport in finite and semi-infinite media are complicated. Sophisticated numerical methods were required in order to implement the solutions as computer programs. These steps are detailed in the report. The main part of this report are illustrations of the solutions with problems in nuclear waste disposal. We show the transport of two chains, uranium 234 to radium 226 and curium 245 to thorium, from concentration-limited boundary condition and Bateman-type boundary condition, in a porous region of limited extent such as a backfill and in a semi-infinite field. These illustrations are examples of the capabilities and usefulness of these solutions. 5 refs., 33 figs

  19. Contribution to study of effects consecutive to alpha decay of uranium 238 in some uranium compounds and uranium ores

    International Nuclear Information System (INIS)

    Ordonez-Regil, E.

    1985-06-01

    The consequences of alpha decay of 238 U in uranium compounds and in uranium bearing ores have been examined in two ways: leaching of 234 Th and determination of the activity ratio of 234 U and 238 U. The results have been interpreted mainly in terms of the ''hot'' character of the nascent 234 Th atoms [fr

  20. LEAF: a computer program to calculate fission product release from a reactor containment building for arbitrary radioactive decay chains

    International Nuclear Information System (INIS)

    Lee, C.E.; Apperson, C.E. Jr.; Foley, J.E.

    1976-10-01

    The report describes an analytic containment building model that is used for calculating the leakage into the environment of each isotope of an arbitrary radioactive decay chain. The model accounts for the source, the buildup, the decay, the cleanup, and the leakage of isotopes that are gas-borne inside the containment building

  1. LEAF: a computer program to calculate fission product release from a reactor containment building for arbitrary radioactive decay chains

    Energy Technology Data Exchange (ETDEWEB)

    Lee, C.E.; Apperson, C.E. Jr.; Foley, J.E.

    1976-10-01

    The report describes an analytic containment building model that is used for calculating the leakage into the environment of each isotope of an arbitrary radioactive decay chain. The model accounts for the source, the buildup, the decay, the cleanup, and the leakage of isotopes that are gas-borne inside the containment building.

  2. A model for short alpha-neurotoxin bound to nicotinic acetylcholine receptor from Torpedo californica: comparison with long-chain alpha-neurotoxins and alpha-conotoxins.

    Science.gov (United States)

    Mordvintsev, D Yu; Polyak, Ya L; Levtsova, O V; Tourleigh, Ye V; Kasheverov, I E; Shaitan, K V; Utkin, Yu N; Tsetlin, V I

    2005-12-01

    Short-chain alpha-neurotoxins from snakes are highly selective antagonists of the muscle-type nicotinic acetylcholine receptors (nAChR). Although their spatial structures are known and abundant information on topology of binding to nAChR is obtained by labeling and mutagenesis studies, the accurate structure of the complex is not yet known. Here, we present a model for a short alpha-neurotoxin, neurotoxin II from Naja oxiana (NTII), bound to Torpedo californica nAChR. It was built by comparative modeling, docking and molecular dynamics using 1H NMR structure of NTII, cross-linking and mutagenesis data, cryoelectron microscopy structure of Torpedo marmorata nAChR [Unwin, N., 2005. Refined structure of the nicotinic acetylcholine receptor at 4A resolution. J. Mol. Biol. 346, 967-989] and X-ray structures of acetylcholine-binding protein (AChBP) with agonists [Celie, P.H., van Rossum-Fikkert, S.E., van Dijk, W.J., Brejc, K., Smit, A.B., Sixma, T.K., 2004. Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures. Neuron 41 (6), 907-914] and antagonists: alpha-cobratoxin, a long-chain alpha-neurotoxin [Bourne, Y., Talley, T.T., Hansen, S.B., Taylor, P., Marchot, P., 2005. Crystal structure of Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors. EMBO J. 24 (8), 1512-1522] and alpha-conotoxin [Celie, P.H., Kasheverov, I.E., Mordvintsev, D.Y., Hogg, R.C., van Nierop, P., van Elk, R., van Rossum-Fikkert, S.E., Zhmak, M.N., Bertrand, D., Tsetlin, V., Sixma, T.K., Smit, A.B., 2005. Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant. Nat. Struct. Mol. Biol. 12 (7), 582-588]. In complex with the receptor, NTII was located at about 30 A from the membrane surface, the tip of its loop II plunges into the ligand-binding pocket between the alpha/gamma or alpha/delta nAChR subunits, while the loops I and III

  3. Description of new element Z=113 and its α-decay chain

    International Nuclear Information System (INIS)

    Tai Fei; Chen Dinghan; Xu Chang; Ren Zhongzhou; National Laboratory of Heavy Ion Accelerator, Lanzhou

    2005-01-01

    RIKEN has produced a new element Z=113 by cold-fusion reaction. Here we systematically study the new nuclide 278 113 and its α-Decay chain using deformed relativistic mean-field theory with three sets of force parameters, TMA, NL-Z2 and NL3. The results are compared with those of the Skyrme-Hartree-Fock model, Moeller et al and also with the new experimental data. The experimental decay energies are well reproduced with RMF. This not only shows the validity of self-consistent field theoretical model in researching the ground state properties of superheavy nuclei, but also shows that prolate deformation is important for the ground state of these nuclei. (authors)

  4. Diffusion and decay chain of radioisotopes in stagnant water in saturated porous media.

    Science.gov (United States)

    Guzmán, Juan; Alvarez-Ramirez, Jose; Escarela-Pérez, Rafael; Vargas, Raúl Alejandro

    2014-09-01

    The analysis of the diffusion of radioisotopes in stagnant water in saturated porous media is important to validate the performance of barrier systems used in radioactive repositories. In this work a methodology is developed to determine the radioisotope concentration in a two-reservoir configuration: a saturated porous medium with stagnant water is surrounded by two reservoirs. The concentrations are obtained for all the radioisotopes of the decay chain using the concept of overvalued concentration. A methodology, based on the variable separation method, is proposed for the solution of the transport equation. The novelty of the proposed methodology involves the factorization of the overvalued concentration in two factors: one that describes the diffusion without decay and another one that describes the decay without diffusion. It is possible with the proposed methodology to determine the required time to obtain equal injective and diffusive concentrations in reservoirs. In fact, this time is inversely proportional to the diffusion coefficient. In addition, the proposed methodology allows finding the required time to get a linear and constant space distribution of the concentration in porous mediums. This time is inversely proportional to the diffusion coefficient. In order to validate the proposed methodology, the distributions in the radioisotope concentrations are compared with other experimental and numerical works. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. Development of a computational algorithm for the linearization of decay and transmutation chains

    International Nuclear Information System (INIS)

    Cruz L, C. A.; Francois L, J. L.

    2017-09-01

    One of the most used methodologies to solve Bate man equations, in the problem of burning, is the Tta (Transmutation Trajectory Analysis) method. In this method, a network of decays is broken down into linear elements known as trajectories, through a process known as linearization. In this work an alternative algorithm is shown to find and construct these trajectories, which considers three aspects of linearization: the information -a priori- about the elements that make up decay and transmutation network, the use of a new notation, and in the functions for the treatment of text strings (which are common in most programming languages). One of the main advantages of the algorithm is that can condense the information of a decay and transmutation network into only two vectors. From these is possible to determine how many linear chains can be extracted from the network and even their length (in the case they are not cyclical). Unlike the Deep First Search method, which is widely used for the linearization process, the method proposed in the present work does not have a backward routine and instead occupies a process of compilation, since completes fragments chain instead of going back to the beginning of the trajectories. The developed algorithm can be applied in a general way to the information search and to the linearization of the computational data structures known as trees. It can also be applied to engineering problems where one seeks to calculate the concentration of some substance as a function of time, starting from linear differential equations of balance. (Author)

  6. Measurement of the CKM Angle Alpha at the BABAR Detector Using B Meson Decays to Rho Final States

    Energy Technology Data Exchange (ETDEWEB)

    Mihalyi, Attila; /Wisconsin U., Madison

    2006-10-16

    This thesis contains the results of an analysis of B{sup 0} {yields} {rho}{sup +}{rho}{sup -} using 232 million {Upsilon}(4S) {yields} B{bar B} decays collected with the BABAR detector at the PEP-II asymmetric-energy B Factory at SLAC. From a fitted signal yield of 617 {+-} 52 events, the longitudinal polarizations fraction, f{sub L}, of the decay is measured to be 0.978 {+-} 0.014(stat){sub -0.029}{sup +0.021}(syst). The nearly fully longitudinal dominance of the B{sup 0} {yields} {rho}{sup +}{rho}{sup -} decay allows for a measurement of the time dependent CP parameters S{sub L} and C{sub L}, where the first parameter is sensitive to mixing induced CP violation and the second one to direct CP violation. From the same signal yield, these values are found to be S{sub L} = -0.33 {+-} 0.24(stat){sub -0.14}{sup +0.08}(syst) and C{sub L} = - 0.03 {+-} 0.18(stat) {+-} 0.09(syst). The CKM angle {alpha} is then determined, using these results and the branching fractions and polarizations of the decays B{sup 0} {yields} {rho}{sup 0}{rho}{sup 0} and B{sup +} {yields} {rho}{sup +}{rho}{sup 0}. This measurement is done with an isospin analysis, in which a triangle is constructed from the isospin amplitudes of these three decay modes. A {chi}{sup 2} expression that includes the measured quantities expressed as the lengths of the sides of the isospin triangles is constructed and minimized to determine a confidence level on {alpha}. Selecting the solution compatible with the Standard Model, one obtains {alpha} = 100{sup o} {+-} 13{sup o}.

  7. Half-lives for proton emission, alpha decay, cluster radioactivity, and cold fission processes calculated in a unified theoretical framework

    International Nuclear Information System (INIS)

    Duarte, S.B.; Tavares, O.A.P.; Guzman, F.; Dimarco, A.; Garcia, F.; Goncalves, M.

    2002-01-01

    Half-life values of spontaneous nuclear decay processes are presented in the framework of the Effective Liquid Drop Model (ELDM) using the combination of varying mass asymmetry shape description for the mass transfer with Werner-Wheeler's inertia coefficient V MAS /WW. The calculated half-lives of ground-state to ground-state transitions for the proton emission, alpha decay, cluster radioactivity, and cold fission processes are compared with experimental data. Results have shown that the ELDM is a very efficient model to describe these different decay processes in a same, unified theoretical framework. A Table listing the predicted half-life values, τ c is presented for all possible cases of spontaneous nuclear break-up such that -7.30 10 τ c [S] 10 (τ/τ c ) > -17.0, where τ is the total half-life of the parent nucleus. (author)

  8. Temperature dependence of decay time and intensity of alpha pulses in pure and thallium-activated cesium iodide

    Science.gov (United States)

    Senftle, F.E.; Martinez, P.; Alekna, V.P.

    1962-01-01

    The intensity and decay time of Po210 ?? particle scintillations produced in pure and thallium-activated cesium iodide have been measured with a fast electronic system as a function of temperature down to 77??K. Three modes of decay due to alpha excitation have been observed for CsI(Tl), and two for CsI. Other than the 7- and 0.55-??sec modes (at room temperature) reported in the literature for CsI(Tl), an additional temperature-independent mode of about 1.3 ??sec has been detected between 77 and 150??K. In CsI a fast temperature-dependent mode of decay (???100 nsec) was observed between 100-200??K in addition to the known principal mode. ?? 1962 The American Institute of Physics.

  9. Heavy Chain Diseases

    Science.gov (United States)

    ... heavy chain produced: Alpha Gamma Mu Alpha Heavy Chain Disease Alpha heavy chain disease (IgA heavy chain ... disease or lead to a remission. Gamma Heavy Chain Disease Gamma heavy chain disease (IgG heavy chain ...

  10. CINDER, Depletion and Decay Chain Calculation for Fission Products in Thermal Reactors

    International Nuclear Information System (INIS)

    England, T.R.; Gorrell, T.C.; Hightower, J.H.

    2001-01-01

    1 - Description of problem or function: CINDER is a four-group, one- point depletion and fission product program based on the evaluation of a general analytical solution of nuclides coupled in any linear sequence of radioactive decays and neutron absorptions in a specified neutron flux spectrum. The desired depletion and fission product chains and all physical data are specified by the problem originator. The program computes individual nuclide number densities, activities, nine energy-group disintegration rates, and macroscopic and barns/fission poisons at each time-step as well as selected summaries of these data. 2 - Method of solution: Time-dependent variations in nuclide cross sections and neutron fluxes are approximated by a user-specified sequential set of values which are considered constant during the duration of the user-specified associated time-increments. When a nuclide concentration is independent of the concentration of any of its progeny, it is possible to resolve the couplings so as to obtain nuclides fed by a single parent. These chains are referred to as linear. 3 - Restrictions on the complexity of the problem: The program is limited to 500 total nuclides formed in up to 240 chains of 20 or fewer nuclides each. Up to 10 nuclides may act as fission product sources, contributing to power, and as many as 99 time-steps of arbitrary length are permitted. All stable nuclides must have a cross section if zero power time-increments are anticipated

  11. New evaluation of alpha decay half-life of 190Pt isotope for the Pt-Os dating system

    International Nuclear Information System (INIS)

    Tavares, O.A.P.; Medeiros, E.L.; Terranova, M.L.

    2005-08-01

    A semiempirical model based on the quantum mechanical tunnelling mechanism of alpha emission from nuclei has been used to evaluate the half-life of the Pt isotopes. For the important naturally occurring 190 Pt isotope, the radiogenic parent in the 190 Pt → 186 Os dating system, the model yielded a half-life value of (3.7± 0.3) versus 10 11 y. This is comparable to (3.2±0.1) versus 10 11 y which was obtained in the last direct counting experiment to measure the alpha activity of 190 Pt (Tavares and Terranova, Rad. Measurem. 27 (1997) 19). A literature survey of available alpha decay half-life values for 190 Pt isotope is also reported. The significant discrepancies found between data obtained by direct counting, indirect geological methods and different calculation models are analysed and discussed. (author)

  12. Transfer of radionuclides at the uranium and thorium decay chains in aquatic and terrestrial environments

    International Nuclear Information System (INIS)

    Letourneau, C.

    1987-04-01

    This report examines the transfer of radionuclides from the uranium and thorium decay chains (U-238, Ra-226, Th-232, Th-230, Po-210 and Pb-210) through the aquatic and terrestrial environment. This transfer is characterized by a transfer coefficient; environmental and experimental factors which cause this coefficient to vary are presented and discussed in this report. Furthermore, based on a literature survey, the report indicates the range of coefficients found for the aquatic sector (that is, sediment and freshwater and marine organisms) and for the terrestrial sector (that is, plants and domestic and wild animals). Afterwards, generalisations are formulated on the transfer of the different radionuclides through the multiple environmental compartments. 75 refs

  13. The deportment of uranium decay chain radionuclides during processing of an Australian monazite concentrate using a caustic conversion route

    International Nuclear Information System (INIS)

    Mellodee Anvia; Brown, S.A.; McOrist, G.D.

    2015-01-01

    Monazite is conventionally processed using caustic conversion and hydrochloric acid leaching in industry, to recover the rare earth elements (REE). Understanding the deportment of uranium decay chain radionuclides is of particular importance for product quality and occupational health and safety (OH and S) purposes. Here, the deportment of uranium decay chain radionuclides during the alkaline treatment route was investigated for the first time, using analytical techniques. Significant quantities of 226 Ra, 210 Pb and 227 Ac were found to report to the rare earth chloride liquor. Subsequent impurity removal treatment generally resulted in the elimination of more than 85 % of radionuclides contained in the chloride liquor. (author)

  14. Chain length dependence of the helix orientation in Langmuir-Blodgett monolayers of alpha-helical diblock copolypeptides

    NARCIS (Netherlands)

    Nguyen, Le-Thu T.; Ardana, Aditya; Vorenkamp, Eltjo J.; ten Brinke, Gerrit; Schouten, Arend J.

    2010-01-01

    The effect of chain length on the helix orientation of alpha-helical diblock copolypeptides in Langmuir and Langmuir-Blodgett monolayers is reported for the first time. Amphiphilic diblock copolypeptides (PLGA-b-PMLGSLGs) of poly(alpha-L-glutamic acid) (PLGA) and

  15. Hypoxia favors myosin heavy chain beta gene expression in an Hif-1alpha-dependent manner.

    Science.gov (United States)

    Binó, Lucia; Procházková, Jiřina; Radaszkiewicz, Katarzyna Anna; Kučera, Jan; Kudová, Jana; Pacherník, Jiří; Kubala, Lukáš

    2017-10-13

    The potentiation of the naturally limited regenerative capacity of the heart is dependent on an understanding of the mechanisms that are activated in response to pathological conditions such as hypoxia. Under these conditions, the expression of genes suggested to support cardiomyocyte survival and heart adaptation is triggered. Particularly important are changes in the expression of myosin heavy chain (MHC) isoforms. We propose here that alterations in the expression profiles of MHC genes are induced in response to hypoxia and are primarily mediated by hypoxia inducible factor (HIF). In in vitro models of mouse embryonic stem cell-derived cardiomyocytes, we showed that hypoxia (1% O 2 ) or the pharmacological stabilization of HIFs significantly increased MHCbeta ( Myh7 ) gene expression. The key role of HIF-1alpha is supported by the absence of these effects in HIF-1alpha-deficient cells, even in the presence of HIF-2alpha. Interestingly, ChIP analysis did not confirm the direct interaction of HIF-1alpha with putative HIF response elements predicted in the MHCalpha and beta encoding DNA region. Further analyses showed the significant effect of the mTOR signaling inhibitor rapamycin in inducing Myh7 expression and a hypoxia-triggered reduction in the levels of antisense RNA transcripts associated with the Myh7 gene locus. Overall, the recognized and important role of HIF in the regulation of heart regenerative processes could be highly significant for the development of novel therapeutic interventions in heart failure.

  16. [Antioxidant effectiveness of short-chain alpha-tocopherol acetate in acute paracetamol poisoning in rats].

    Science.gov (United States)

    Shaiakhmetova, H M; Kovalenko, V M; Bondarenko, L B; Kuz'menko, I V

    2000-01-01

    In the experiments in vivo on white rats possibility of paracetamol hepatotoxic effects correction with synthetic short-chain alpha-tocopherol derivative and pharmacopeial preparation of vitamin E has been studied. Levels of superoxide anion generation in liver mitochondria fraction, catalase activity and reduced glutathione, serum aminotransferase and alcaline phosphatase activities and liver subcellular fractions lipid contents were investigated. It was shown that the short-chain vitamin E derivative and pharmacopeial preparation had a membranotropic effect, normalizing free and total cholesterol levels in liver mitochondria fraction and decreasing serum aminotransferase activity level. Investigated compounds also decreased levels of superoxide anions generation, increased catalase activity and level of reduced glutathione in liver. Antioxidative properties of this derivative and pharmacopeial preparation were demonstrated both at the primary (dienes, trienes) and at final steps of lipid peroxidation (TBA-products formation). This antioxidative activity of alpha-tocopherol acetate and its derivative depended on the structure of chromane cycle but not on the length of side chain.

  17. Mechanisms of activation of muscle branched-chain alpha-keto acid dehydrogenase during exercise in man

    DEFF Research Database (Denmark)

    Van Hall, Gerrit; MacLean, D A; Saltin, B

    1996-01-01

    1. Exercise leads to activation (dephosphorylation) of the branched-chain alpha-keto acid dehydrogenase (BCKADH). Here we investigate the effect of low pre-exercise muscle glycogen content and of branched-chain amino acid (BCAA) ingestion on the activity of BCKADH at rest and after 90 min of one...

  18. A study of membrane protein defects and alpha hemoglobin chains of red blood cells in human beta thalassemia

    International Nuclear Information System (INIS)

    Rouyer-Fessard, P.; Garel, M.C.; Domenget, C.; Guetarni, D.; Bachir, D.; Colonna, P.; Beuzard, Y.

    1989-01-01

    The soluble pool of alpha hemoglobin chains present in blood or bone marrow cells was measured with a new affinity method using a specific probe, beta A hemoglobin chain labeled with [ 3 H]N-ethylmaleimide. This pool of soluble alpha chains was 0.067 ± 0.017% of hemoglobin in blood of normal adult, 0.11 ± 0.03% in heterozygous beta thalassemia and ranged from 0.26 to 1.30% in homozygous beta thalassemia intermedia. This elevated pool of soluble alpha chains observed in human beta thalassemia intermedia decreased 33-fold from a value of 10% of total hemoglobin in bone marrow cells to 0.3% in the most dense red blood cells. The amount of insoluble alpha chains was measured by using the polyacrylamide gel electrophoresis in urea and Triton X-100. In beta thalassemia intermedia the amount of insoluble alpha chains was correlated with the decreased spectrin content of red cell membrane and was associated with a decrease in ankyrin and with other abnormalities of the electrophoretic pattern of membrane proteins. The loss and topology of the reactive thiol groups of membrane proteins was determined by using [ 3 H]N-ethylmaleimide added to membrane ghosts prior to urea and Triton X-100 electrophoresis. Spectrin and ankyrin were the major proteins with the most important decrease of thiol groups

  19. Evidence for B(0) --> rho(0)rho(0) decays and implications for the Cabibbo-Kobayashi-Maskawa angle alpha.

    Science.gov (United States)

    Aubert, B; Bona, M; Boutigny, D; Karyotakis, Y; Lees, J P; Poireau, V; Prudent, X; Tisserand, V; Zghiche, A; Grauges, E; Palano, A; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Ofte, I; Stugu, B; Abrams, G S; Battaglia, M; Brown, D N; Button-Shafer, J; Cahn, R N; Groysman, Y; Jacobsen, R G; Kadyk, J A; Kerth, L T; Kolomensky, Yu G; Kukartsev, G; Pegna, D Lopes; Lynch, G; Mir, L M; Orimoto, T J; Osipenkov, I; Pripstein, M; Roe, N A; Ronan, M T; Tackmann, K; Wenzel, W A; Sanchez, P Del Amo; Barrett, M; Harrison, T J; Hart, A J; Hawkes, C M; Watson, A T; Held, T; Koch, H; Lewandowski, B; Pelizaeus, M; Peters, K; Schroeder, T; Steinke, M; Boyd, J T; Burke, J P; Cottingham, W N; Walker, D; Asgeirsson, D J; Cuhadar-Donszelmann, T; Fulsom, B G; Hearty, C; Knecht, N S; Mattison, T S; McKenna, J A; Khan, A; Kyberd, P; Saleem, M; Sherwood, D J; Teodorescu, L; Blinov, V E; Bukin, A D; Druzhinin, V P; Golubev, V B; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Todyshev, K Yu; Bondioli, M; Bruinsma, M; Chao, M; Curry, S; Eschrich, I; Kirkby, D; Lankford, A J; Lund, P; Mandelkern, M; Martin, E C; Stoker, D P; Abachi, S; Buchanan, C; Foulkes, S D; Gary, J W; Liu, F; Long, O; Shen, B C; Zhang, L; Hill, E J; Paar, H P; Rahatlou, S; Sharma, V; Berryhill, J W; Campagnari, C; Cunha, A; Dahmes, B; Hong, T M; Kovalskyi, D; Richman, J D; Beck, T W; Eisner, A M; Flacco, C J; Heusch, C A; Kroseberg, J; Lockman, W S; Schalk, T; Schumm, B A; Seiden, A; Williams, D C; Wilson, M G; Winstrom, L O; Chen, E; Cheng, C H; Dvoretskii, A; Fang, F; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Mancinelli, G; Meadows, B T; Mishra, K; Sokoloff, M D; Blanc, F; Bloom, P C; Chen, S; Ford, W T; Hirschauer, J F; Kreisel, A; Nagel, M; Nauenberg, U; Olivas, A; Smith, J G; Ulmer, K A; Wagner, S R; Zhang, J; Chen, A; Eckhart, E A; Soffer, A; Toki, W H; Wilson, R J; Winklmeier, F; Zeng, Q; Altenburg, D D; Feltresi, E; Hauke, A; Jasper, H; Merkel, J; Petzold, A; Spaan, B; Wacker, K; Brandt, T; Klose, V; Lacker, H M; Mader, W F; Nogowski, R; Schubert, J; Schubert, K R; Schwierz, R; Sundermann, J E; Volk, A; Bernard, D; Bonneaud, G R; Latour, E; Thiebaux, Ch; Verderi, M; Clark, P J; Gradl, W; Muheim, F; Playfer, S; Robertson, A I; Xie, Y; Andreotti, M; Bettoni, D; Bozzi, C; Calabrese, R; Cibinetto, G; Luppi, E; Negrini, M; Petrella, A; Piemontese, L; Prencipe, E; Anulli, F; Baldini-Ferroli, R; Calcaterra, A; de Sangro, R; Finocchiaro, G; Pacetti, S; Patteri, P; Peruzzi, I M; Piccolo, M; Rama, M; Zallo, A; Buzzo, A; Contri, R; Vetere, M Lo; Macri, M M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Chaisanguanthum, K S; Morii, M; Wu, J; Dubitzky, R S; Marks, J; Schenk, S; Uwer, U; Bard, D J; Dauncey, P D; Flack, R L; Nash, J A; Nikolich, M B; Vazquez, W Panduro; Behera, P K; Chai, X; Charles, M J; Mallik, U; Meyer, N T; Ziegler, V; Cochran, J; Crawley, H B; Dong, L; Eyges, V; Meyer, W T; Prell, S; Rosenberg, E I; Rubin, A E; Gritsan, A V; Lae, C K; Denig, A G; Fritsch, M; Schott, G; Arnaud, N; Davier, M; Grosdidier, G; Höcker, A; Lepeltier, V; Diberder, F Le; Lutz, A M; Pruvot, S; Rodier, S; Roudeau, P; Schune, M H; Serrano, J; Sordini, V; Stocchi, A; Wang, W F; Wormser, G; Lange, D J; Wright, D M; Chavez, C A; Forster, I J; Fry, J R; Gabathuler, E; Gamet, R; Hutchcroft, D E; Payne, D J; Schofield, K C; Touramanis, C; Bevan, A J; George, K A; Lodovico, F Di; Menges, W; Sacco, R; Cowan, G; Flaecher, H U; Hopkins, D A; Jackson, P S; McMahon, T R; Salvatore, F; Wren, A C; Brown, D N; Davis, C L; Allison, J; Barlow, N R; Barlow, R J; Chia, Y M; Edgar, C L; Lafferty, G D; West, T J; Yi, J I; Chen, C; Hulsbergen, W D; Jawahery, A; Roberts, D A; Simi, G; Blaylock, G; Dallapiccola, C; Hertzbach, S S; Li, X; Moore, T B; Salvati, E; Saremi, S; Cowan, R; Sciolla, G; Sekula, S J; Spitznagel, M; Taylor, F; Yamamoto, R K; Kim, H; McLachlin, S E; Patel, P M; Robertson, S H; Lazzaro, A; Lombardo, V; Palombo, F; Bauer, J M; Cremaldi, L; Eschenburg, V; Godang, R; Kroeger, R; Sanders, D A; Summers, D J; Zhao, H W; Brunet, S; Côté, D; Simard, M; Taras, P; Viaud, F B; Nicholson, H; Cavallo, N; Nardo, G De; Fabozzi, F; Gatto, C; Lista, L; Monorchio, D; Paolucci, P; Piccolo, D; Sciacca, C; Baak, M A; Raven, G; Snoek, H L; Jessop, C P; Losecco, J M; Benelli, G; Corwin, L A; Gan, K K; Honscheid, K; Hufnagel, D; Kagan, H; Kass, R; Morris, J P; Rahimi, A M; Regensburger, J J; Ter-Antonyan, R; Wong, Q K; Blount, N L; Brau, J; Frey, R; Igonkina, O; Kolb, J A; Lu, M; Potter, C T; Rahmat, R; Sinev, N B; Strom, D; Strube, J; Torrence, E; Gaz, A; Margoni, M; Morandin, M; Pompili, A; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Voci, C; Ben-Haim, E; Briand, H; Chauveau, J; David, P; Buono, L Del; de la Vaissière, Ch; Hamon, O; Hartfiel, B L; Leruste, Ph; Malclès, J; Ocariz, J; Gladney, L; Biasini, M

    2007-03-16

    We search for the decays B(0) --> rho(0)rho(0), B(0) --> rho(0)f(0)(980), and B(0) --> f(0)(980)f(0)(980) in a sample of about 384 x 10(6) Upsilon(4S) --> BB[over] decays collected with the BABAR detector at the PEP-II asymmetric-energy e(+)e(-) collider at Stanford Linear Accelerator Center. We find evidence for B(0) --> rho(0)rho(0) with 3.5 sigma significance and measure the branching fraction B = (1.07 +/- 0.33 +/- 0.19) x 10(-6) and longitudinal polarization fraction f(L) = 0.87 +/- 0.13 +/- 0.04, where the first uncertainty is statistical, and the second is systematic. The uncertainty on the Cabibbo-Kobayashi-Maskawa quark-mixing matrix unitarity angle alpha due to penguin contributions in B --> rho rho decays is 18 degrees at the 1 sigma level. We also set upper limits on the B(0) --> rho(0)f(0)(980) and B(0) --> f(0)(980)f(0)(980) decay rates.

  20. Alpha-decay for heavy nuclei in the ground and isomeric states

    Science.gov (United States)

    Dong, Jianmin; Zhang, Hongfei; Wang, Yanzhao; Zuo, Wei; Li, Junqing

    2010-01-01

    The α-decay half-lives of nuclei in the ground states and isomeric states have been calculated within the WKB approximation and Royer's formulas. The barrier in the quasimolecular shape path is determined within a generalized liquid drop model (GLDM), in which the centrifugal potential energy has been introduced to study the unfavored α-decay. The agreement between the calculated results and experimental data indicates the reliability of studying α-decay of isomeric states with the generalized liquid drop model. We find that their is no significant difference of preformation probability between isomeric states and the corresponding ground states generally in favored α-decay. Additionally, we extended Royer's formulas by taking account of the role of centrifugal barrier to study the unfavored α-decay, and some predicts on the α-decay half-lives of isomers are made. Finally, the effects of angular momentum transfer and Q on α-decay half-life have been discussed.

  1. HB KURDISTAN [ALPHA-47(CE5)ASP-]TYR], A NEW ALPHA-CHAIN VARIANT IN COMBINATION WITH BETA-THALASSEMIA

    NARCIS (Netherlands)

    GIORDANO, PC; HARTEVELD, CL; STRENG, H; Oosterwijk, Jan; HEISTER, JGAM; AMONS, R; BERNINI, LF

    1994-01-01

    We have characterized the structural abnormality of a new alpha chain mutant found in a Kurdish; family. The clinical and hematological investigation of eight individuals have shown that the a variant is associated with a beta degrees-thalassemia mutation (nonsense codon 39). The tryptic peptide map

  2. Pre-equilibrium decay process in alpha particle induced reactions on thulium and tantalum

    Energy Technology Data Exchange (ETDEWEB)

    Mohan, Rao, A.V.; Chintalapudi, S.N. (Inter Univ. Consortium for Dept. of atomic Energy Facilities, Calcutta (India))

    1994-01-01

    Alpha particle induced reactions on the target elements Thulium and Tantalum were investigated upto 60 MeV using stacked foil activation technique and Ge(Li) gamma ray spectroscopy method. Excitation functions for six reactions of [sup 169]Tm([alpha],xn); x=1-4 and [sup 181]Ta([alpha],xn); x=2,4 were studied. The experimental results were compared with the updated version of Hybrid model (ALICE/90) using initial exciton configuration n[sub 0]=4(4pOh). A general agreement was found for all the reactions with this option. (author).

  3. Uranium, thorium and their decay products in human food-chain

    International Nuclear Information System (INIS)

    Jeambrun, M.

    2012-01-01

    Uranium, thorium and their decay products are present in trace amounts in all rocks on Earth. Weathering, Mechanisms of soil formation and soil-plant transfers lead to the presence of these radionuclides in all the components of the environment and, through the food-chain transfers, they are also present in animals and men. The objective of this study consists in improving the knowledge on the levels and the variability of the activities of these radionuclides in various foodstuffs and on their sources and transfers. This study is based on the geological variability of the studied sites (granitic, volcanic and alluvial areas) where various foodstuffs are sampled (vegetables, cereals, meat, eggs and dairy products). The possible sources of radionuclides (irrigation waters and soils for plants; water, food and soils for animals) are also sampled in order to study their contribution to the measured activities in the foodstuffs. The results obtained present high variability of the activities in plants, less pronounced in animal products. For plants, the main radionuclide source seems to be the crop soils. Irrigation water, soil particle resuspension and their adhesion to plant surface seems to be important in some cases. For the activities in animal products, a significant contribution of the soil to thorium activity was highlighted. Water contribution to uranium activity in meat and eggs is an area worth further researches. Thus, this study of the possible sources of radionuclides highlights the importance of their role in the understanding of the radionuclide transfers to foodstuffs. (author)

  4. First Accurate Normalization of the $\\beta$-delayed $\\alpha$ Decay of $^{16}$N and Implications for the $^{12}$C$(\\alpha,\\gamma)^{16}$O Astrophysical Reaction Rate arXiv

    CERN Document Server

    Kirsebom, O.S.; Lica, R.; Munch, M.; Riisager, K.; Fynbo, H.O.U.; Borge, M.J.G.; Madurga, M.; Marroquin, I.; Andreyev, A.N.; Berry, T.A.; Christensen, E.R.; Fernández, P. Díaz; Doherty, D.T.; Van Duppen, P.; Fraile, L.M.; Gallardo, M.C.; Greenlees, P.T.; Harkness-Brennan, L.J.; Hubbard, N.; Huyse, M.; Jensen, J.H.; Johansson, H.; Jonson, B.; Judson, D.S.; Konki, J.; Lazarus, I.; Lund, M.V.; Marginean, N.; Marginean, R.; Perea, A.; Mihai, C.; Negret, A.; Page, R.D.; Pucknell, V.; Rahkila, P.; Sorlin, O.; Sotty, C.; Swartz, J.A.; Sørensen, H.B.; Törnqvist, H.; Vedia, V.; Warr, N.; De Witte, H.

    The $^{12}$C$(\\alpha,\\gamma)^{16}$O reaction plays a central role in astrophysics, but its cross section at energies relevant for astrophysical applications is only poorly constrained by laboratory data. The reduced $\\alpha$ width, $\\gamma_{11}$, of the bound $1^-$ level in $^{16}$O is particularly important to determine the cross section. The magnitude of $\\gamma_{11}$ is determined via sub-Coulomb $\\alpha$-transfer reactions or the $\\beta$-delayed $\\alpha$ decay of $^{16}$N, but the latter approach is presently hampered by the lack of sufficiently precise data on the $\\beta$-decay branching ratios. Here we report improved branching ratios for the bound $1^-$ level and for $\\beta$-delayed $\\alpha$ emission. In the case of the $\\beta$-delayed $\\alpha$ branch, we find a $5\\sigma$ deviation from the literature value. With our new branching ratios, the constraints imposed on $\\gamma_{11}$ by the $\\beta\\alpha$-decay and $\\alpha$-transfer data are of similar precision and, for the first time, in good agreement. Th...

  5. New search for correlated e{sup +}e{sup -} pairs in the {alpha} decay of {sup 241}Am

    Energy Technology Data Exchange (ETDEWEB)

    Bernabei, R.; Belli, P.; Di Marco, A. [INFN, Sezione Roma ' ' Tor Vergata' ' , Rome (Italy); Universita di Roma ' ' Tor Vergata' ' , Dipartimento di Fisica, Rome (Italy); Cappella, F.; D' Angelo, A.; Incicchitti, A. [INFN, Sezione Roma, Rome (Italy); Universita di Roma ' ' La Sapienza' ' , Dipartimento di Fisica, Rome (Italy); Caracciolo, V.; Castellano, S.; Cerulli, R.; Laubenstein, M. [Laboratori Nazionali del Gran Sasso, INFN, Assergi (Italy); Dai, C.J.; He, H.L.; Ma, X.H.; Sheng, X.D.; Wang, R.G. [Chinese Academy, IHEP, Beijing (China); Montecchia, F. [INFN, Sezione Roma ' ' Tor Vergata' ' , Rome (Italy); Universita di Roma ' ' Tor Vergata' ' , Dipartimento di Ingegneria Civile e Ingegneria Informatica, Rome (Italy); Tretyak, V.I. [Institute for Nuclear Research, Kyiv (Ukraine); Ye, Z.P. [Chinese Academy, IHEP, Beijing (China); University of Jing Gangshan, Jiangxi (China)

    2013-05-15

    A new search for production of correlated e{sup +}e{sup -} pairs in the {alpha} decay of {sup 241}Am has been carried out deep underground at the Gran Sasso National Laboratory of the INFN by using pairs of NaI(Tl) detectors of the DAMA/LIBRA set-up. The experimental data show an excess of double coincidences of events with energy around 511keV in faced pairs of detectors, which are not explained by known side reactions. This measured excess gives a relative activity {lambda} = (4.70{+-}0.63) x 10{sup -9} for the Internal Pair Production (IPP) with respect to the alpha decay of {sup 241}Am; this value is of the same order of magnitude as previous determinations. In a conservative approach the upper limit {lambda} < 5.5 x 10{sup -9} (90% C.L.) can be derived. It is worth noting that this is the first result on IPP obtained in an underground experiment, and that the {lambda} value obtained in the present work is independent of the live-time estimate. (orig.)

  6. A Study of B0 to rho+rho- Decays and Constraints on theCKM Angle alpha

    Energy Technology Data Exchange (ETDEWEB)

    Aubert, B.

    2007-05-16

    The authors present results from an analysis of B{sup 0} {yields} {rho}{sup +}{rho}{sup -} decays using (383.6 {+-} 4.2) x 10{sup 6} B{bar B} pairs collected by the BABAR detector at the PEP-II asymmetric-energy B Factory at SLAC. The measurements of the B{sup 0} {yields} {rho}{sup +}{rho}{sup -} branching fraction, longitudinal polarization fraction f{sub L}, and the CP-violating parameters S{sub long} and C{sub long} are: {Beta}(B{sup 0} {yields} {rho}{sup +}{rho}{sup -}) = (25.5 {+-} 2.1(stat){sub -3.9}{sup +3.6}(syst)) x 10{sup -6}, f{sub L} = 0.992 {+-} 0.024(stat){sub -0.013}{sup +0.026}(syst), S{sub long} = -0.17 {+-} 0.20(stat){sub -0.06}{sup +0.05}(syst), C{sub long} = 0.01 {+-} 0.15(stat) {+-} 0.06(syst). The authors determine the unitarity triangle angle {alpha}, using an isospin analysis of B {yields} {rho}{rho} decays. One of the two solutions, {alpha} = [73.1, 117.0]{sup o} at 68% CL is compatible with standard model-based fits of existing data. Constraints on the unitarity triangle are also evaluated using an SU(3) symmetry based approach.

  7. Alpha Decay Half-Lives of Exotic Nuclei around Shell Closures

    Science.gov (United States)

    Wang, Y. Z.; Gu, Q. F.; Dong, J. M.; Peng, B. B.

    In the framework of the generalized liquid drop model (GLDM) and improved Royer's formula with a set of new coefficients derived by N. D. Schubert et al. [Eur. Phys. J. A 42 (2009) 121], the favored and unfavored α-decay half-lives of exotic nuclei around closed shells Z = 82 and N = 126 are investigated. The calculated results are in good agreement with the experimental data. It is shown that our method can be used to study the α-decay half-lives of exotic nuclei around shell closures successfully and is helpful for future research on superheavy nuclei around the next proton and neutron shell closures. In addition, some α-decay half-lives for the cases where the experimental values are unavailable are predicted. We hope our predicted results are useful for future experiments.

  8. Half-lives for proton emission, alpha decay, cluster radioactivity, and cold fission processes calculated in a unified theoretical framework

    Energy Technology Data Exchange (ETDEWEB)

    Duarte, S.B.; Tavares, O.A.P.; Guzman, F.; Dimarco, A. [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil); Garcia, F. [Sao Paulo Univ., SP (Brazil). Inst. de Fisica; Universidade Estadual de Santa Cruz, Ilheus, BA (Brazil). Dept. de Ciencias Exatas e Tecnologicas; Rodriguez, O. [Sao Paulo Univ., SP (Brazil). Inst. de Fisica; Instituto Superior de Ciencias e Tecnologia Nucleares, La Habana (Cuba); Goncalves, M. [Instituto de Radioprotecao e Dosimetria (IRD), Rio de Janeiro, RJ (Brazil)

    2002-01-01

    Half-life values of spontaneous nuclear decay processes are presented in the framework of the Effective Liquid Drop Model (ELDM) using the combination of varying mass asymmetry shape description for the mass transfer with Werner-Wheeler's inertia coefficient V{sub MAS}/WW. The calculated half-lives of ground-state to ground-state transitions for the proton emission, alpha decay, cluster radioactivity, and cold fission processes are compared with experimental data. Results have shown that the ELDM is a very efficient model to describe these different decay processes in a same, unified theoretical framework. A Table listing the predicted half-life values, {tau}{sub c} is presented for all possible cases of spontaneous nuclear break-up such that -7.30 <{approx_equal} log{sub 10} {tau}{sub c} [S] <{approx_equal} 27.50 and log {sub 10}({tau}/{tau}{sub c}) > -17.0, where {tau} is the total half-life of the parent nucleus. (author)

  9. Preparation and isolation of antibodies to human MHC class II alpha chains by aid of synthetic peptides.

    Science.gov (United States)

    Chersi, A; Romano, T F; Chillemi, F

    1989-01-01

    Antibodies against HLA Class II alpha chains were prepared by using as immunogens synthetic peptides selected from the HLA-DQ1 alpha chains sequence. Antibodies raised against peptide E2, a 15-residue fragment of the polymorphic first domain, reacted preferentially with cells with the DQ1 phenotype; however, despite the low sequence homology of this fragment with corresponding segments in DQw2 and DQw3 alpha chains, a partial crossreactivity with cells not expressing the DQw1 specificity was detected. Antibodies to peptide H, selected from the monomorphic frame, might be specific for DQ alloantigens, and presumably do not react with DR antigens. The two peptides, in addition, bind anti-Class II antibodies from the serum of a rabbit immunized with human cells, and appear to represent immunogenic linear determinants in the native glycoprotein molecule.

  10. Fetal antigen 2: an amniotic protein identified as the aminopropeptide of the alpha 1 chain of human procollagen type I

    DEFF Research Database (Denmark)

    Teisner, B; Rasmussen, H B; Højrup, P

    1992-01-01

    with the aminopropeptide of the alpha 1 chain of human procollagen type I as determined by nucleotide sequences. After oxidative procedures normally employed for radio-iodination (iodogen and chloramine-T), FA2 lost its immunoreactivity. An antigen which cross-reacted with polyclonal rabbit anti-human FA2 was demonstrated...... to that of FA2 in human skin. FA2 is a circulating form of the aminopropeptide of the alpha 1 chain of procollagen type I, and this is the first description of its isolation and structural characterization in humans. Udgivelsesdato: 1992-Dec...

  11. Behavior of /sup 232/Th and the /sup 238/U decay chain nuclides during magma formation and volcanism

    Energy Technology Data Exchange (ETDEWEB)

    Krishnaswami, S.; Turekian, K.K.; Bennett, J.T. (Yale Univ., New Haven, CT (USA). Dept. of Geology and Geophysics)

    1984-03-01

    Concentrations of the members of the /sup 238/U decay chain and /sup 232/Th were determined in volcanic rocks from convergent plate margins, intraplate volcanoes and oceanic spreading centers. Contemporary and historical volcanic rocks from Mt. St. Helens, Arenal, El Chichon, Hawaii and Iceland and submarine basaltic glass from the Galapagos spreading center all show no fractionation of U and Th in the mantle source or during magma formation at least for the past 300,000 years. Mauna Kea (Hawaii) rocks of alkaline composition greater than 4000 years old and an old submarine basalt show disequilibrium for several of the nuclides in the /sup 238/U decay chain. We interpret these as resulting from post-emplacement processes.

  12. A shortened beta-hexosaminidase alpha-chain in an Italian patient with infantile Tay-Sachs disease.

    Science.gov (United States)

    Zokaeem, G; Bayleran, J; Kaplan, P; Hechtman, P; Neufeld, E F

    1987-01-01

    Fibroblasts derived from a beta-hexosaminidase A (HexA)-deficient infant with clinically classic Tay-Sachs disease synthesized a precursor alpha-chain that was smaller than its normal counterpart. Fibroblasts from the infant's parents, who were consanguinous, produced both normal and mutant alpha-chains. The size difference, estimated to be 2-3 kilodaltons on the basis of sodium dodecyl sulfate-polyacrylamide-gel electrophoresis, persisted after removal of oligosaccharides with endo-H and is therefore attributable to a shortened polypeptide. The mutant alpha-chain did not undergo the further posttranslational modifications characteristic of its normal counterpart--i.e., synthesis of the mannose phosphate recognition marker, association with the beta-chain to give HexA, and proteolytic conversion to the mature form. Nor was it secreted, even in the presence of NH4Cl. Instead, it disappeared in the course of a 20-h chase. These results suggest that the mutant alpha-chain was trapped in an early biosynthetic compartment, either the endoplasmic reticulum or the cis-Golgi. The mutation appears to be different from all those previously described in patients with clinically classic Tay-Sachs disease. Images Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 5 Fig. 6 PMID:2954459

  13. The Effect of Herbal Mouthwashes on the Force Decay of Elastomeric Chains: An In-vitro Study

    Directory of Open Access Journals (Sweden)

    Mohammed Nahidh

    2017-10-01

    Full Text Available Background: This in vitro study aimed to evaluate the effect of four herbal mouthwashes on the force decay of two types of clear short elastomeric chains (Regular and Extreme at various time intervals. Materials and methods: Four hundred forty pieces of both types of elastomeric chains with 19 mm length were utilized in this study. The force was measured, using digital scale immediately, after one-day immersion in distilled water and after 1, 2, 3 and 4 weeks immersion in the specific mouthwash for one minute twice daily then washed and kept in distilled water at 37°C. Force decay was calculated and compared among different elastic types, mouthwashes and time intervals using t-test and one-way ANOVA then Tukey’s tests. Results: The force degradation of regular type was significantly higher than extreme one. With time, the force decay increased significantly in both types. There was non-significant difference among the mouthwashes in the first and second weeks while the opposite in the third and fourth especially with the control group. Conclusions: The extreme type is preferred over the regular one because of its low force decay and the tested mouthwashes have no clinical significant effect on the force degradation over time in comparison with distilled water.

  14. Radioactive Decay

    Science.gov (United States)

    Radioactive decay is the emission of energy in the form of ionizing radiation. Example decay chains illustrate how radioactive atoms can go through many transformations as they become stable and no longer radioactive.

  15. Contaminant transport in fractured porous media: analytical solution for a two-member decay chain in a single fracture

    International Nuclear Information System (INIS)

    Sudicky, E.A.; Frind, E.O.

    1984-01-01

    An analytical solution is presented for the problem of radionuclide chain decay during transport through a discrete fracture situated in a porous rock matrix. The solution takes into account advection along the fracture, molecular diffusion from the fracture to the porous matrix, adsorption on the fracture face, adsorption in the rock matrix, and radioactive decay. The solution for the daughter product is in the form of a double integral which is evaluated by Gauss-Legendre quadrature. Results show that the daughter product tends to advance ahead of the parent nuclide even when the half-life of the parent is larger. This is attributed to the effect of chain decay in the matrix, which tends to reduce the diffusive loss of the daughter along the fracture. The examples also demonstrate that neglecting the parent nuclide and modeling its daughter as a single species can result in significant overestimation of arrival times at some point along the fracture. Although the analytical solution is restricted to a two-member chain for practical reasons, it represents a more realistic description of nuclide transport along a fracture than available single-species models. The solution may be of use for application to other contaminants undergoing different types of first-order transformation reactions

  16. Predictions on the modes of decay of even Z superheavy isotopes within the range 104 ≤ Z ≤ 136

    Science.gov (United States)

    Santhosh, K. P.; Nithya, C.

    2018-01-01

    The decay modes and half lives of all the even Z isotopes of superheavy elements within the range 104 ≤ Z ≤ 136 have been predicted by comparing the alpha decay half-lives with the spontaneous fission half-lives. The Coulomb and proximity potential model for deformed nuclei (CPPMDN) and the shell-effect-dependent formula of Santhosh et al. are used to calculate the alpha half-lives and spontaneous fission half-lives respectively. For theoretical comparison the alpha decay half-lives are also calculated using Coulomb and proximity potential model (CPPM), the Viola-Seaborg-Sobiczewski semi-empirical (VSS) relation, the universal (UNIV) curve of Poenaru et al., the analytical formula of Royer and the universal decay law (UDL) of Qi et al. Another tool used for the evaluation of spontaneous fission half-lives is the semi-empirical formula of Xu et al. The nuclei with alpha decay half-lives less than spontaneous fission half-lives will survive fission and hence decay through alpha emission. The predicted half lives and decay modes are compared with the available experimental results. The one-proton and two-proton separation energies of all the isotopes are calculated to find nuclei which lie beyond the proton drip line. Among 1119 even Z nuclei within the range 104 ≤ Z ≤ 136, 164 nuclei show sequential alpha emission followed by subsequent spontaneous fission. Since the isotopes decay through alpha decay chain and the half-lives are in measurable range, these isotopes are predicted to be synthesized and detected in laboratory via alpha decay. 2 nuclei will decay by alpha decay followed by proton emission, 54 nuclei show full alpha chains, 642 nuclei will decay through spontaneous fission, 166 nuclei exhibit proton decay and 91 isotopes are found to be stable against alpha decay. All the isotopes are tabulated according to their decay modes. The study is intended to enhance further experimental investigations in superheavy region.

  17. Pre-equilibrium decay process in alpha particle induced reactions on thulium and tantalum

    International Nuclear Information System (INIS)

    Mohan, Rao, A.V.; Chintalapudi, S.N.

    1994-01-01

    Alpha particle induced reactions on the target elements Thulium and Tantalum were investigated upto 60 MeV using stacked foil activation technique and Ge(Li) gamma ray spectroscopy method. Excitation functions for six reactions of 169 Tm(α,xn); x=1-4 and 181 Ta(α,xn); x=2,4 were studied. The experimental results were compared with the updated version of Hybrid model (ALICE/90) using initial exciton configuration n 0 =4(4pOh). A general agreement was found for all the reactions with this option. (author)

  18. The predicted 10.6 keV transition in Fr-221 from the alpha-decay of Ac-225 revealed

    Czech Academy of Sciences Publication Activity Database

    Yakushev, E. A.; Chumin, V. G.; Gorozhankin, VM.; Gromov, KY.; Kovalík, Alojz; Filosofov, D. V.; Norseev, YV.; Yurkova, LV.

    2002-01-01

    Roč. 28, č. 3 (2002), s. 463-467 ISSN 0954-3899 R&D Projects: GA ČR GA202/02/0157 Institutional research plan: CEZ:AV0Z1048901 Keywords : electromagnetic transition * electron conversion * alpha-decay Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders Impact factor: 1.399, year: 2002

  19. Alpha chain hemoglobins with electrophoretic mobility similar to that of hemoglobin S in a newborn screening program

    Directory of Open Access Journals (Sweden)

    Marcilene Rezende Silva

    2013-01-01

    Full Text Available OBJECTIVE: To characterize alpha-chain variant hemoglobins with electric mobility similar to that of hemoglobin S in a newborn screening program. METHODS: βS allele and alpha-thalassemia deletions were investigated in 14 children who had undefined hemoglobin at birth and an electrophoretic profile similar to that of hemoglobin S when they were six months old. Gene sequencing and restriction enzymes (DdeI, BsaJI, NlaIV, Bsu36I and TaqI were used to identify hemoglobins. Clinical and hematological data were obtained from children who attended scheduled medical visits. RESULTS: The following alpha chain variants were found: seven children with hemoglobin Hasharon [alpha2 47(CE5 Asp>His, HbA2:c.142G>C], all associated with alpha-thalassemia, five with hemoglobin Ottawa [alpha1 15(A13 Gly>Arg, HBA1:c.46G>C], one with hemoglobin St Luke's [alpha1 95(G2 Pro>Arg, HBA1:c.287C>G] and another one with hemoglobin Etobicoke [alpha212 84(F5 Ser>Arg, HBA212:c.255C>G]. Two associations with hemoglobin S were found: one with hemoglobin Ottawa and one with hemoglobin St Luke's. The mutation underlying hemoglobin Etobicoke was located in a hybrid α212 allele in one child. There was no evidence of clinically relevant hemoglobins detected in this study. CONCLUSION: Apparently these are the first cases of hemoglobin Ottawa, St Luke's, Etobicoke and the α212 gene described in Brazil. The hemoglobins detected in this study may lead to false diagnosis of sickle cell trait or sickle cell disease when only isoelectric focusing is used in neonatal screening. Additional tests are necessary for the correct identification of hemoglobin variants.

  20. Alpha chain hemoglobins with electrophoretic mobility similar to that of hemoglobin S in a newborn screening program.

    Science.gov (United States)

    Silva, Marcilene Rezende; Sendin, Shimene Mascarenhas; Araujo, Isabela Couto de Oliveira; Pimentel, Fernanda Silva; Viana, Marcos Borato

    2013-01-01

    To characterize alpha-chain variant hemoglobins with electric mobility similar to that of hemoglobin S in a newborn screening program. β(S) allele and alpha-thalassemia deletions were investigated in 14 children who had undefined hemoglobin at birth and an electrophoretic profile similar to that of hemoglobin S when they were six months old. Gene sequencing and restriction enzymes (DdeI, BsaJI, NlaIV, Bsu36I and TaqI) were used to identify hemoglobins. Clinical and hematological data were obtained from children who attended scheduled medical visits. THE FOLLOWING ALPHA CHAIN VARIANTS WERE FOUND: seven children with hemoglobin Hasharon [alpha2 47(CE5) Asp>His, HbA2:c.142G>C], all associated with alpha-thalassemia, five with hemoglobin Ottawa [alpha1 15(A13) Gly>Arg, HBA1:c.46G>C], one with hemoglobin St Luke's [alpha1 95(G2) Pro>Arg, HBA1:c.287C>G] and another one with hemoglobin Etobicoke [alpha212 84(F5) Ser>Arg, HBA212:c.255C>G]. Two associations with hemoglobin S were found: one with hemoglobin Ottawa and one with hemoglobin St Luke's. The mutation underlying hemoglobin Etobicoke was located in a hybrid α212 allele in one child. There was no evidence of clinically relevant hemoglobins detected in this study. Apparently these are the first cases of hemoglobin Ottawa, St Luke's, Etobicoke and the α212 gene described in Brazil. The hemoglobins detected in this study may lead to false diagnosis of sickle cell trait or sickle cell disease when only isoelectric focusing is used in neonatal screening. Additional tests are necessary for the correct identification of hemoglobin variants.

  1. Unfolded HLA class I alpha chains and their use in an assay of HLA class-I-peptide binding.

    Science.gov (United States)

    Tanigaki, N; Fruci, D; Chersi, A; Butler, R H

    1993-02-01

    Unfolded HLA class I alpha chains were isolated from B-cell lysates by alkaline denaturation and subsequent gel filtration and used for the detection of HLA class-I-peptide binding. Binding to specific peptides in the presence of excess beta 2-microglobulin induced the unfolded alpha chains to refold and acquire a conformation that is specific to folded alpha chains. This conformational change was measured by a specific RIA that involves inhibition of the binding of 125I-labeled HLA-A2 alpha/beta dimers and rabbit anti-HLA-B7 serum absorbed with beta 2-microglobulin. This assay procedure does not require labeling of either test peptides or test class I proteins and does not seem to have specificity degeneracy. It is applicable to the detection of peptide binding by all HLA class I allelic proteins. Evaluation of the assay conditions and HLA allelic specificity of the peptide binding defined by the use of synthetic peptides are described here, including the technical details, specificity, and reproducibility.

  2. Transfer of the uranium decay products, polonium-210 and lead-210, through the lichen-caribou-wolf food chain in northern Canada (manuscript report)

    International Nuclear Information System (INIS)

    Thomas, P.A.

    1991-05-01

    The main purpose of this study is to investigate the accumulation and transfer of polonium-210 and lead-210 in the arctic food chain, lichen-caribou-wolf, in the Northwest Territories. Polonium-210 arises from lead-210 decay and is a widespread alpha-emitting radionuclide. It seeks soft tissue and has the potential to accumulate in the food chain. Caribou, wolves and other wildlife may become exposed to enhanced levels of these two uranium-series radionuclides if the proposed uranium mine near Baker Lake, Northwest Territories, proceeds. Baker Lake lies at the crossroads of the ranges of the Beverly, the Kaminuriak and the Wager Bay caribou herds. Therefore, it is important to establish baseline concentrations and natural food chain transfer of uranium series radionuclides, in this study. This information can be used for baseline data before any further mining development takes place. This study will also provide data regarding the statistical uncertainty attached to transfer coefficients. This can help ensure reliable and appropriate future monitoring of environmental change. With the participation of the hunters of Baker Lake, caribou and wolf samples were collected and analyzed for polonium. Results indicate that polonium-210 activity in caribou tissues were somewhat higher than previous data reported from Alaska. Transfer coefficients for polonium-210 from caribou to wolf were near unity for many tissues. However, polonium-210 does not appear to cross the placenta in caribou. Further study includes lichen collections and collection of further caribou samples from the beverly herd in order to determine transfer from lichens to caribou in both the Baker Lake and Snowdrift areas in the Northwest Territories. (author). 26 refs., 3 tabs

  3. Separation and characterization of alpha-chain subunits from tilapia (Tilapia zillii) skin gelatin using ultrafiltration.

    Science.gov (United States)

    Chen, Shulin; Tang, Lanlan; Su, Wenjin; Weng, Wuyin; Osako, Kazufumi; Tanaka, Munehiko

    2015-12-01

    Alpha-chain subunits were separated from tilapia skin gelatin using ultrafiltration, and the physicochemical properties of obtained subunits were investigated. As a result, α1-subunit and α2-subunit could be successfully separated by 100 kDa MWCO regenerated cellulose membranes and 150 kDa MWCO polyethersulfone membranes, respectively. Glycine was the most dominant amino acid in both α1-subunit and α2-subunit. However, the tyrosine content was higher in α2-subunit than in α1-subunit, resulting in strong absorption near 280 nm observed in the UV absorption spectrum. Based on the DSC analysis, it was found that the glass transition temperatures of gelatin, α1-subunit and α2-subunit were 136.48 °C, 126.77 °C and 119.43 °C, respectively. Moreover, the reduced viscosity and denaturation temperature of α1-subunit were higher than those of α2-subunit, and the reduced viscosity reached the highest when α-subunits were mixed with α1/α2 ratio of approximately 2, suggesting that α1-subunit plays a more important role in the thermostability of gelatin than α2-subunit. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. The limits of the nuclear chart set by fission and alpha decay

    Directory of Open Access Journals (Sweden)

    Möller Peter

    2016-01-01

    Full Text Available I will review how our picture of heavy-element nuclear structure has evolved through remarkably simple ideas and related models. It is well known that the Bethe-Weizsäcker semi-empirical mass model had an important role in unraveling radioactive decay and element transmutation in the heavy-element region in the 1930s. A remarkable aspect is that this model could immediately after the discovery of fission be generalized to explain this phenomenon through the consideration of deformation of a charged liquid drop. Bethe and Bacher already raised the possibility that shell structure (by them calculated in terms of a single-particle oscillator potential could give rise to noticeable deviations between results of the macroscopic mass model and experiment but limited data prevented firm conclusions. In the 1950s the single-particle models took a realistic form and also included deformation. The possibility of the existence of a relatively stable “island” of superheavy elements was raised already then. But it was not until the work by Strutinsky in the mid 1960s that a quantitative model for the nuclear potential-energy emerged in the form of the macroscopic-microscopic model. Although new elements have been discovered at an almost steady pace since 1940, theory indicates that we are close to the end of this era: repulsive Coulomb effects will set the limit of observable elements to near Z = 120.

  5. Reply to: ''Improved Determination of the CKM Angle alpha from B -> pipi decays''

    CERN Document Server

    Charles, J.; Lacker, H.; Le Diberder, F.; T'Jampens, S.

    2007-01-01

    In reply to hep-ph/0701204 we demonstrate why the arguments made therein do not address the criticism exposed in hep-ph/0607246 on the fundamental shortcomings of the Bayesian approach when it comes to the extraction of parameters of Nature from experimental data. As for the isospin analysis and the CKM angle alpha it is shown that the use of uniform priors for the observed quantities in the Explicit Solution parametrization is equivalent to a frequentist construction resulting from a change of variables, and thus relies neither on prior PDFs nor on Bayes' theorem. This procedure provides in this particular case results that are similar to the Confidence Level approach, but the treatment of mirror solutions remains incorrect and it is far from being general. In a second part it is shown that important differences subsist between the Bayesian and frequentist approaches, when following the proposal of hep-ph/0701204 and inserting additional information on the hadronic amplitudes beyond isospin invariance. In pa...

  6. From beta-relaxation to alpha-decay: Atomistic picture from molecular dynamics simulations for glass-forming Ni0.5Zr0.5 melt

    Energy Technology Data Exchange (ETDEWEB)

    Teichler, Helmar [Inst. Materialphysik, Univ Goettingen (Germany)

    2013-07-01

    In glass-forming melts the decay of structural fluctuation shows the well known transition from beta-relaxation (von-Schweidler law with exponent b) to alpha-decay (KWW law with exponent beta). Here we present results from molecular dynamics simulations for a metallic glass forming Ni0.5Zr0.5 model aimed at giving an understanding of this transition on the atomistic scale. At the considered temperature below mode coupling Tc, the dynamics of the system can be interpreted by residence of the particles in their neighbour cages and escape from the cages as rare processes. Our analysis yields that the fraction of residing particles is characterized by a hierarchical law in time, with von-Schweidler b explicitly related to the exponent of this law. In the alpha-decay regime the stretching exponent reflects, in addition, floating of the cages due to strain effects of escaped particles. Accordingly, the change from beta-relaxation to alpha-decay indicates the transition from low to large fraction of escaped particles.

  7. A study of the recombination scheme dependence of jet production rates and of. alpha. sub s (Msub(Z sub 0 )) in hadronic Z sup 0 decays

    Energy Technology Data Exchange (ETDEWEB)

    Akrawy, M.Z.; Alexander, G.; Allison, J.; Allport, P.P.; Anderson, K.J.; Armitage, J.C.; Arnison, G.T.J.; Ashton, P.; Azuelos, G.; Baines, J.T.M.; Ball, A.H.; Banks, J.; Barker, G.J.; Barlow, R.J.; Batley, J.R.; Beck, A.; Becker, J.; Behnke, T.; Bell, K.W.; Bella, G.; Bethke, S.; Biebel, O.; Binder, U.; Bloodworth, I.J.; Bock, P.; Breuker, H.; Brown, R.M.; Brun, R.; Buijs, A.; Burckhart, H.J.; Capiluppi, P.; Carnegie, R.K.; Carter, A.A.; Carter, J.R.; Chang, C.Y.; Charlton, D.G.; Chrin, J.T.M.; Clarke, P.E.L.; Cohen, I.; Collins, W.J.; Conboy, J.E.; Couch, M.; Coupland, M.; Cuffiani, M.; Dado, S.; Dallavalle, G.M.; Debu, P.; Deninno, M.M.; Dieckmann, A.; Dittmar, M.; Dixit, M.S.; Duchovni, E.; Duerdoth, I.P.; Dumans, D.J.P.; Elcombe, P.A.; Estabrooks, P.G.; Etzion, E.; Fabbri, F.; Farthouat, P.; Fischer, H.M.; Fong, D.G.; French, M.T.; Fukunaga, C.; Gaidot, A.; Ganel, O.; Gary, J.W.; Gascon, J.; Geddes, N.I.; Gee, C.N.P.; Geich-Gimbel, C.; Gensler, S.W.; Gentit, F.X.; Giacomelli, G.; G; OPAL Collaboration

    1991-02-01

    Jet production rates in hadronic Z{sup 0} decays are studied using four different recombination schemes to define resolvable jets. The strong coupling constant {alpha}{sub s}(Msub(Z{sup 0})) is determined in fits of the corresponding O({alpha}{sub s}{sup 2}) QCD calculations to the differential 2-jet distributions D{sub 2}(y). Hadronisation corrections and renormalisation scale uncertainties are found to be different for each recombination scheme. Within their overall systematic uncertainties, the four schemes yield consistent values of {alpha}{sub s}(Msub(Z{sup 0})), leading to a final result of {alpha}{sub s}(Msub(Z{sup 0}))=0.118{plus minus}0.008. The error includes the experimental uncertainties ({plus minus}0.003), uncertainties of hadronisation corrections and of the degree of parton virtualities to which the data are corrected, as well as the uncertainty of choosing the renormalisation scale. (orig.).

  8. Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus

    Directory of Open Access Journals (Sweden)

    Podisi Baitsi

    2009-06-01

    Full Text Available Abstract Background The comparative analysis of genome sequences emerging for several avian species with the fully sequenced chicken genome enables the genome-wide investigation of selective processes in functionally important chicken genes. In particular, because of pathogenic challenges it is expected that genes involved in the chicken immune system are subject to particularly strong adaptive pressure. Signatures of selection detected by inter-species comparison may then be investigated at the population level in global chicken populations to highlight potentially relevant functional polymorphisms. Results Comparative evolutionary analysis of chicken (Gallus gallus and zebra finch (Taeniopygia guttata genes identified interleukin 4 receptor alpha-chain (IL-4Rα, a key cytokine receptor as a candidate with a significant excess of substitutions at nonsynonymous sites, suggestive of adaptive evolution. Resequencing and detailed population genetic analysis of this gene in diverse village chickens from Asia and Africa, commercial broilers, and in outgroup species red jungle fowl (JF, grey JF, Ceylon JF, green JF, grey francolin and bamboo partridge, suggested elevated and balanced diversity across all populations at this gene, acting to preserve different high-frequency alleles at two nonsynonymous sites. Conclusion Haplotype networks indicate that red JF is the primary contributor of diversity at chicken IL-4Rα: the signature of variation observed here may be due to the effects of domestication, admixture and introgression, which produce high diversity. However, this gene is a key cytokine-binding receptor in the immune system, so balancing selection related to the host response to pathogens cannot be excluded.

  9. Solute transport in a single fracture involving an arbitrary length decay chain with rock matrix comprising different geological layers.

    Science.gov (United States)

    Mahmoudzadeh, Batoul; Liu, Longcheng; Moreno, Luis; Neretnieks, Ivars

    2014-08-01

    A model is developed to describe solute transport and retention in fractured rocks. It accounts for advection along the fracture, molecular diffusion from the fracture to the rock matrix composed of several geological layers, adsorption on the fracture surface, adsorption in the rock matrix layers and radioactive decay-chains. The analytical solution, obtained for the Laplace-transformed concentration at the outlet of the flowing channel, can conveniently be transformed back to the time domain by the use of the de Hoog algorithm. This allows one to readily include it into a fracture network model or a channel network model to predict nuclide transport through channels in heterogeneous fractured media consisting of an arbitrary number of rock units with piecewise constant properties. More importantly, the simulations made in this study recommend that it is necessary to account for decay-chains and also rock matrix comprising at least two different geological layers, if justified, in safety and performance assessment of the repositories for spent nuclear fuel. Copyright © 2014 Elsevier B.V. All rights reserved.

  10. Effect of low electric fields on alpha scintillation light yield in liquid argon

    Science.gov (United States)

    Agnes, P.; Albuquerque, I. F. M.; Alexander, T.; Alton, A. K.; Asner, D. M.; Back, H. O.; Baldin, B.; Biery, K.; Bocci, V.; Bonfini, G.; Bonivento, W.; Bossa, M.; Bottino, B.; Brigatti, A.; Brodsky, J.; Budano, F.; Bussino, S.; Cadeddu, M.; Cadoni, M.; Calaprice, F.; Canci, N.; Candela, A.; Caravati, M.; Cariello, M.; Carlini, M.; Catalanotti, S.; Cavalcante, P.; Chepurnov, A.; Cicalò, C.; Cocco, A. G.; Covone, G.; D'Angelo, D.; D'Incecco, M.; Davini, S.; De Cecco, S.; De Deo, M.; De Vincenzi, M.; Derbin, A.; Devoto, A.; Di Eusanio, F.; Di Pietro, G.; Dionisi, C.; Edkins, E.; Empl, A.; Fan, A.; Fiorillo, G.; Fomenko, K.; Forster, G.; Franco, D.; Gabriele, F.; Galbiati, C.; Giagu, S.; Giganti, C.; Giovanetti, G. K.; Goretti, A. M.; Granato, F.; Gromov, M.; Guan, M.; Guardincerri, Y.; Hackett, B. R.; Herner, K.; Hughes, D.; Humble, P.; Hungerford, E. V.; Ianni, A.; James, I.; Johnson, T. N.; Jollet, C.; Keeter, K.; Kendziora, C. L.; Koh, G.; Korablev, D.; Korga, G.; Kubankin, A.; Li, X.; Lissia, M.; Loer, B.; Lombardi, P.; Longo, G.; Ma, Y.; Machulin, I. N.; Mandarano, A.; Mari, S. M.; Maricic, J.; Marini, L.; Martoff, C. J.; Meregaglia, A.; Meyers, P. D.; Milincic, R.; Miller, J. D.; Montanari, D.; Monte, A.; Mount, B. J.; Muratova, V. N.; Musico, P.; Napolitano, J.; Navrer Agasson, A.; Odrowski, S.; Oleinik, A.; Orsini, M.; Ortica, F.; Pagani, L.; Pallavicini, M.; Pantic, E.; Parmeggiano, S.; Pelczar, K.; Pelliccia, N.; Pocar, A.; Pordes, S.; Pugachev, D. A.; Qian, H.; Randle, K.; Ranucci, G.; Razeti, M.; Razeto, A.; Reinhold, B.; Renshaw, A. L.; Rescigno, M.; Riffard, Q.; Romani, A.; Rossi, B.; Rossi, N.; Rountree, D.; Sablone, D.; Saggese, P.; Sands, W.; Savarese, C.; Schlitzer, B.; Segreto, E.; Semenov, D. A.; Shields, E.; Singh, P. N.; Skorokhvatov, M. D.; Smirnov, O.; Sotnikov, A.; Stanford, C.; Suvorov, Y.; Tartaglia, R.; Tatarowicz, J.; Testera, G.; Tonazzo, A.; Trinchese, P.; Unzhakov, E. V.; Verducci, M.; Vishneva, A.; Vogelaar, B.; Wada, M.; Walker, S.; Wang, H.; Wang, Y.; Watson, A. W.; Westerdale, S.; Wilhelmi, J.; Wojcik, M. M.; Xiang, X.; Xiao, X.; Xu, J.; Yang, C.; Zhong, W.; Zhu, C.; Zuzel, G.

    2017-01-01

    Measurements were made of scintillation light yield of alpha particles from the 222Rn decay chain within the DarkSide-50 liquid argon time projection chamber. The light yield was found to increase as the applied electric field increased, with alphas in a 200 V/cm electric field exhibiting a ~2% increase in light yield compared to alphas in no field.

  11. Tissue-specific expression of the human laminin alpha5-chain, and mapping of the gene to human chromosome 20q13.2-13.3 and to distal mouse chromosome 2 near the locus for the ragged (Ra) mutation

    DEFF Research Database (Denmark)

    Durkin, M E; Loechel, F; Mattei, M G

    1997-01-01

    To investigate the function of the laminin alpha5-chain, previously identified in mice, cDNA clones encoding the 953-amino-acid carboxy terminal G-domain of the human laminin alpha5-chain were characterized. Northern blot analysis showed that the laminin alpha5-chain is expressed in human placenta...

  12. Alpha decay of neutron-deficient isotopes with 52

    CERN Document Server

    Schardt, D; Kirchner, R; Klepper, O; Kurcewicz, W; Roeckl, E; Tidemand-Petersson, P

    1981-01-01

    Using /sup 58/Ni(/sup 58/Ni, xpyn) reactions and on-line mass separation, the alpha -decays of very neutron-deficient isotopes of tellurium, iodine, xenon and cesium were studied. The new isotopes /sup 106/Te (T/sub 1/2/=60/sub -10//sup +30/ mu s) and /sup 110/Xe were identified by their alpha -lines of 4160+or-30 keV and 3737+or-30 keV energy, respectively, with the genetic relationship between the two successive alpha -decays being verified experimentally, while for several other alpha -decaying isotopes more precise data were obtained. The observed alpha -decay properties are discussed within the systematics of energy and reduced width. (19 refs).

  13. Determination of the Dalitz plot parameter {alpha} for the decay {eta}{yields}3{pi}{sup 0} with the Crystal Ball at MAMI-B

    Energy Technology Data Exchange (ETDEWEB)

    Unverzagt, M.; Beck, R.; Lang, M.; Nikolaev, A.; Schumann, S. [University Mainz, Institut fuer Kernphysik, Mainz (Germany); University Bonn, Helmholtz-Institut fuer Strahlen- und Kernphysik, Bonn (Germany); Aguar-Bartolome, P.; Ahrens, J.; Arends, H.J.; Heid, E.; Jahn, O.; Krambrich, D.; Martinez-Fabregate, M.; Rost, M.; Thomas, A.; Walcher, T. [University Mainz, Institut fuer Kernphysik, Mainz (Germany); Annand, J.R.M.; Codling, R.; Livingston, K.; MacGregor, I.J.D.; McGeorge, J.C.; Owens, R.O.; Rosner, G. [University of Glasgow, Department of Physics and Astronomy, Glasgow (United Kingdom); Bekrenev, V. [Petersburg Nuclear Physics Institute, Gatchina (Russian Federation); Boillat, B.; Krusche, B.; Zehr, F. [University Basel, Institut fuer Physik, Basel (Switzerland); Braghieri, A.; Pedroni, P.; Rostomyan, T. [INFN Sezione di Pavia, Pavia (Italy); Branford, D.; Glazier, D.I.; Tarbert, C.M.; Watts, D.P. [Univ. of Edinburgh, School of Physics, Edinburgh (United Kingdom); Briscoe, W.J. [The George Washington Univ., Center for Nuclear Studies, Washington, D.C. (United States); Brudvik, J.W.; Nefkens, B.M.K.; Prakhov, S.N.; Price, J.W.; Starostin, A. [Univ. of California at Los Angeles, Los Angeles, CA (United States); Cherepnya, S.; Fil' kov, L.V.; Kashevarov, V.L. [Lebedev Physical Inst., Moscow (Russian Federation); Downie, E.J. [Univ. Mainz, Inst. fuer Kernphysik, Mainz (Germany); Univ. of Glasgow, Dept. of Physics and Astronomy, Glasgow (United Kingdom); Gregor, R.; Kotulla, M.; Lugert, S.; Metag, V.; Novotny, R. [Univ. Giessen, II. Physikalisches Inst., Giessen (Germany); Hornidge, D. [Mount Allison Univ., Sackville, NB (Canada); Kondratiev, R.; Lisin, V.; Polonski, A. [Institute for Nuclear Research, Moscow (Russian Federation); Korolija, M.; Mekterovic, D.; Supek, I. [Rudjer Boskovic Inst., Zagreb (Croatia); Manley, D.M. [Kent State Univ., Kent, OH (United States); Sober, D. [The Catholic Univ. of America, Washington, D.C. (United States)

    2009-02-15

    A precise measurement of the Dalitz plot parameter, {alpha}, for the {eta}{yields}3{pi}{sup 0} decay is presented. The experiment was performed with the Crystal Ball and TAPS large-acceptance photon detectors at the tagged photon beam facility of the MAMI-B electron accelerator in Mainz. High statistics of 1.8.10{sup 6} {eta}{yields}3{pi}{sup 0} events were obtained, giving the result {alpha}=-0.032{+-}0.002{sub stat}{+-}0.002{sub syst}. (orig.)

  14. The GDR in Hg and Eu nuclei from selected decay chains

    CERN Document Server

    Camera, F; Colombo, G; Leoni, S; Million, B; Mattiuzzi, M; Maj, A; Kmiecik, M; Herskind, B; Bark, R; Bearden, J; Gaardhøje, J J; Ormand, E W

    1999-01-01

    The gamma-decay of the GDR in hot Hg and Eu isotopes has been measured in coincidence with selected low-energy gamma-transitions of the evaporation residues. In the Hg case, the GDR width at finite temperature and at different spins was studied by analyzing simultaneously with the statistical model the high-energy gamma-ray spectra associated with different residual nuclei and the fractions of residue cross-sections. The measured GDR width was found in good agreement with the predictions of the thermal fluctuations model. In the case of Eu, we have measured the high-energy gamma-rays in coincidence with low-energy gamma-transitions from different nuclear configurations of sup 1 sup 4 sup 3 Eu in order to search for the GDR decay built on a superdeformed state. The analysis of the data shows a possible evidence of this state. The measured intensity indicates that the superdeformation survives only few MeV above the yrast line.

  15. Probing the charged Higgs quantum numbers through the decay H{sup +}{sub {alpha}} {yields} W{sup +}h{sup 0}{sub s}s

    Energy Technology Data Exchange (ETDEWEB)

    Diaz-Cruz, J L [Cuerpo Academico de PartIculas, Campos y Relatividad de la BUAP (Mexico); Felix-Beltran, O [Instituto de Fisica, UNAM, Apdo. Postal 20-364, Mexico 01000 D.F. (Mexico); Hernandez-Sanchez, J [Universidad Autonoma del Estado de Hidalgo, Carretera a Pachuca Tulancingo Km. 4.5, C. U., C.P. 42020, Pachuca Hidalgo (Mexico); Barradas-Guevara, E [Cuerpo Academico de PartIculas, Campos y Relatividad de la BUAP (Mexico)

    2006-05-15

    The vertex H{sup +}{sub {alpha}} {yields} W{sup -}h{sup 0}{sub s}s, involving the gauge boson W{sup {+-}} and the charged (H{sup {+-}}{sub {alpha}}) and neutral Higgs bosons (h{sup 0}{sub s}s), arises within the context of many extensions of the SM, and it can be used to probe the quantum numbers of the Higgs multiplet. After presenting a general discussion for the expected form of this vertex for arbitrary Higgs representations, we discuss its strength for an extended MSSM with one complex triplet. We find that in this model, there are regions of parameters where the decay H{sup +}{sub {alpha}} {yields} W{sup +}h{sup 0}{sub s}s, is kinematically allowed, and reaches Branching Ratios (BR) that may be detectable, thus allowing to test the properties of the Higgs sector.

  16. Determination of the isomeric fraction in a postaccelerated radioactive ion beam using the coupled decay-chain equations

    CERN Document Server

    Ekstrom, A; Dijulio, D D; Cederkall, J; Van de Walle, J

    2010-01-01

    A method based on the coupled decay-chain equations for extracting the isotopic and the isomeric composition of a postaccelerated radioactive ion beam is presented and demonstrated on a data set from a Coulomb excitation experiment. This is the first attempt of analyzing the content of a postaccelerated radioactive ion beam using this technique. The beam composition is required for an absolute normalization of the measurement. The strength of the method, as compared to present online-based methods, lies in the determination of the isomeric fraction of a partially isomeric beam using all data accumulated during the experiment. We discuss the limitations and sensitivity of the method with respect to the gamma-ray detection efficiency and the accumulated flux. (C) 2010 Elsevier B.V. All rights reserved.

  17. Radionuclide migration through fractured rock for arbitrary-length decay chain: Analytical solution and global sensitivity analysis

    Science.gov (United States)

    Shahkarami, Pirouz; Liu, Longcheng; Moreno, Luis; Neretnieks, Ivars

    2015-01-01

    This study presents an analytical approach to simulate nuclide migration through a channel in a fracture accounting for an arbitrary-length decay chain. The nuclides are retarded as they diffuse in the porous rock matrix and stagnant zones in the fracture. The Laplace transform and similarity transform techniques are applied to solve the model. The analytical solution to the nuclide concentrations at the fracture outlet is governed by nine parameters representing different mechanisms acting on nuclide transport through a fracture, including diffusion into the rock matrices, diffusion into the stagnant water zone, chain decay and hydrodynamic dispersion. Furthermore, to assess how sensitive the results are to parameter uncertainties, the Sobol method is applied in variance-based global sensitivity analyses of the model output. The Sobol indices show how uncertainty in the model output is apportioned to the uncertainty in the model input. This method takes into account both direct effects and interaction effects between input parameters. The simulation results suggest that in the case of pulse injections, ignoring the effect of a stagnant water zone can lead to significant errors in the time of first arrival and the peak value of the nuclides. Likewise, neglecting the parent and modeling its daughter as a single stable species can result in a significant overestimation of the peak value of the daughter nuclide. It is also found that as the dispersion increases, the early arrival time and the peak time of the daughter decrease while the peak value increases. More importantly, the global sensitivity analysis reveals that for time periods greater than a few thousand years, the uncertainty of the model output is more sensitive to the values of the individual parameters than to the interaction between them. Moreover, if one tries to evaluate the true values of the input parameters at the same cost and effort, the determination of priorities should follow a certain

  18. Association between genetic polymorphisms in the human interleukin-7 receptor alpha-chain and inhalation allergy

    DEFF Research Database (Denmark)

    Shamim, Z; Müller, K; Svejgaard, A

    2007-01-01

    Thymic stromal-derived lymphopoietin (TSLP) and interleukin-7 share a common receptor chain, IL-7Ralpha. IL-7 is involved in T-cell homeostasis, and TSLP induces production of pro-allergic cytokines. The gene encoding the IL-7Ralpha chain is polymorphic, and investigation of inhalation allergic p...

  19. Mutation in the alpha 5(IV) collagen chain in juvenile-onset Alport syndrome without hearing loss or ocular lesions

    DEFF Research Database (Denmark)

    Zhou, J; Hertz, Jens Michael; Tryggvason, K

    1992-01-01

    A single base mutation was identified in the type IV collagen alpha 5 chain gene (COL4A5) of a Danish kindred with Alport syndrome. The 27-year-old male proband developed hematuria in childhood and terminal renal failure at the age of 25 years. He has no hearing loss or ocular lesions. Electron.......9-kb fragments present in control DNA but the presence of a 2.2-kb variant fragment, indicating the loss of an MspI restriction site in the 3' end of the gene. The mother had all three fragments, indicating heterozygosity. PCR amplification of exon 14 (counted from the 3' end) and subsequent denaturing...

  20. Theoretical studies on the alpha α decay half-lives of hyper and normal isotopes of Po

    Science.gov (United States)

    Santhosh, K. P.; Nithya, C.

    2018-03-01

    The α decay half-lives of hyper and normal isotopes of Po nuclei are studied in the present work. The inclusion of Λ - N interaction changes the half-life for α decay. The theoretical predictions on the α decay half-lives of normal Po isotopes are compared with experimental results and are seen to be matching well with each other. The neutron shell closure at N = 126 is found to be the same for both normal and hypernuclei. The Geiger-Nuttal (G-N) law for α decay is unaltered in the case of hypernuclei. The hypernuclei will decay into normal nuclei by mesonic or non-mesonic decay modes. Since the half-lives of normal Po nuclei are well within the experimental limits, our theoretical results suggest experimental verification of the α emission from hyper Po nuclei in a cascade process.

  1. Urine of patients with early prostate cancer contains lower levels of light chain fragments of inter-alpha-trypsin inhibitor and saposin B but increased expression of an inter-alpha-trypsin inhibitor heavy chain 4 fragment.

    Science.gov (United States)

    Jayapalan, Jaime J; Ng, Keng L; Shuib, Adawiyah S; Razack, Azad H A; Hashim, Onn H

    2013-06-01

    The present study was aimed at the identification of proteins that are differentially expressed in the urine of patients with prostate cancer (PCa), those with benign prostatic hyperplasia (BPH) and age-matched healthy male control subjects. Using a combination of 2DE and MS/MS, significantly lower expression of urinary saposin B and two different fragments of inter-alpha-trypsin inhibitor light chain (ITIL) was demonstrated in the PCa patients compared to the controls. However, only one of the ITIL fragments was significantly different between the PCa and BPH patients. When image analysis was performed on urinary proteins that were transferred onto NC membranes and detected using a lectin that binds to O-glycans, a truncated fragment of inter-alpha-trypsin inhibitor heavy chain 4 was the sole protein found to be significantly enhanced in the PCa patients compared to the controls. Together, these urinary peptide fragments might be useful complementary biomarkers to indicate PCa as well as to distinguish it from BPH, although further epidemiological evidence on the specificity and sensitivity of the protein candidates is required. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Measurement of the spectral functions of axial-vector hadronic $\\tau$ decays and determination of $\\alpha_{s}(M^2_\\tau)$

    CERN Document Server

    Barate, R; Décamp, D; Ghez, P; Goy, C; Lees, J P; Lucotte, A; Merle, E; Minard, M N; Nief, J Y; Pietrzyk, B; Alemany, R; Boix, G; Casado, M P; Chmeissani, M; Crespo, J M; Delfino, M C; Fernández, E; Fernández-Bosman, M; Garrido, L; Graugès-Pous, E; Juste, A; Martínez, M; Merino, G; Miquel, R; Mir, L M; Park, I C; Pascual, A; Perlas, J A; Riu, I; Sánchez, F; Colaleo, A; Creanza, D; De Palma, M; Gelao, G; Iaselli, Giuseppe; Maggi, G; Maggi, M; Nuzzo, S; Ranieri, A; Raso, G; Ruggieri, F; Selvaggi, G; Silvestris, L; Tempesta, P; Tricomi, A; Zito, G; Huang, X; Lin, J; Ouyang, Q; Wang, T; Xie, Y; Xu, R; Xue, S; Zhang, J; Zhang, L; Zhao, W; Abbaneo, D; Becker, U; Bright-Thomas, P G; Casper, David William; Cattaneo, M; Ciulli, V; Dissertori, G; Drevermann, H; Forty, Roger W; Frank, M; Hagelberg, R; Hansen, J B; Harvey, J; Janot, P; Jost, B; Lehraus, Ivan; Mato, P; Minten, Adolf G; Moneta, L; Pacheco, A; Pusztaszeri, J F; Ranjard, F; Rolandi, Luigi; Rousseau, D; Schlatter, W D; Schmitt, M; Schneider, O; Tejessy, W; Teubert, F; Tomalin, I R; Wachsmuth, H W; Wagner, A; Ajaltouni, Ziad J; Badaud, F; Chazelle, G; Deschamps, O; Falvard, A; Ferdi, C; Gay, P; Guicheney, C; Henrard, P; Jousset, J; Michel, B; Monteil, S; Montret, J C; Pallin, D; Perret, P; Podlyski, F; Proriol, J; Rosnet, P; Hansen, J D; Hansen, J R; Hansen, P H; Nilsson, B S; Rensch, B; Wäänänen, A; Daskalakis, G; Kyriakis, A; Markou, C; Simopoulou, Errietta; Siotis, I; Vayaki, Anna; Blondel, A; Bonneaud, G R; Brient, J C; Bourdon, P; Rougé, A; Rumpf, M; Valassi, Andrea; Verderi, M; Videau, H L; Focardi, E; Parrini, G; Zachariadou, K; Corden, M; Georgiopoulos, C H; Jaffe, D E; Antonelli, A; Bencivenni, G; Bologna, G; Bossi, F; Campana, P; Capon, G; Cerutti, F; Chiarella, V; Felici, G; Laurelli, P; Mannocchi, G; Murtas, F; Murtas, G P; Passalacqua, L; Pepé-Altarelli, M; Curtis, L; Halley, A W; Lynch, J G; Negus, P; O'Shea, V; Raine, C; Scarr, J M; Smith, K; Teixeira-Dias, P; Thompson, A S; Thomson, E; Buchmüller, O L; Dhamotharan, S; Geweniger, C; Graefe, G; Hanke, P; Hansper, G; Hepp, V; Kluge, E E; Putzer, A; Sommer, J; Tittel, K; Werner, S; Wunsch, M; Beuselinck, R; Binnie, David M; Cameron, W; Dornan, Peter J; Girone, M; Goodsir, S M; Martin, E B; Marinelli, N; Moutoussi, A; Nash, J; Sedgbeer, J K; Spagnolo, P; Williams, M D; Ghete, V M; Girtler, P; Kneringer, E; Kuhn, D; Rudolph, G; Betteridge, A P; Bowdery, C K; Buck, P G; Colrain, P; Crawford, G; Finch, A J; Foster, F; Hughes, G; Jones, R W L; Williams, M I; Giehl, I; Greene, A M; Hoffmann, C; Jakobs, K; Kleinknecht, K; Quast, G; Renk, B; Rohne, E; Sander, H G; Van Gemmeren, P; Zeitnitz, C; Aubert, Jean-Jacques; Benchouk, C; Bonissent, A; Bujosa, G; Carr, J; Coyle, P; Etienne, F; Leroy, O; Motsch, F; Payre, P; Talby, M; Sadouki, A; Thulasidas, M; Trabelsi, K; Aleppo, M; Antonelli, M; Ragusa, F; Berlich, R; Blum, Walter; Büscher, V; Dietl, H; Ganis, G; Kroha, H; Lütjens, G; Mannert, C; Männer, W; Moser, H G; Schael, S; Settles, Ronald; Seywerd, H C J; Stenzel, H; Wiedenmann, W; Wolf, G; Boucrot, J; Callot, O; Chen, S; Cordier, A; Davier, M; Duflot, L; Grivaz, J F; Heusse, P; Höcker, A; Jacholkowska, A; Kim, D W; Le Diberder, F R; Lefrançois, J; Lutz, A M; Schune, M H; Tournefier, E; Veillet, J J; Videau, I; Zerwas, D; Azzurri, P; Bagliesi, G; Batignani, G; Bettarini, S; Boccali, T; Bozzi, C; Calderini, G; Carpinelli, M; Ciocci, M A; Dell'Orso, R; Fantechi, R; Ferrante, I; Foà, L; Forti, F; Giassi, A; Giorgi, M A; Gregorio, A; Ligabue, F; Lusiani, A; Marrocchesi, P S; Messineo, A; Palla, Fabrizio; Rizzo, G; Sanguinetti, G; Sciabà, A; Tenchini, Roberto; Tonelli, G; Vannini, C; Venturi, A; Verdini, P G; Blair, G A; Bryant, L M; Chambers, J T; Green, M G; Medcalf, T; Perrodo, P; Strong, J A; Von Wimmersperg-Töller, J H; Botterill, David R; Clifft, R W; Edgecock, T R; Haywood, S; Norton, P R; Thompson, J C; Wright, A E; Bloch-Devaux, B; Colas, P; Emery, S; Kozanecki, Witold; Lançon, E; Lemaire, M C; Locci, E; Pérez, P; Rander, J; Renardy, J F; Roussarie, A; Schuller, J P; Schwindling, J; Trabelsi, A; Vallage, B; Black, S N; Dann, J H; Johnson, R P; Kim, H Y; Konstantinidis, N P; Litke, A M; McNeil, M A; Taylor, G; Booth, C N; Brew, C A J; Cartwright, S L; Combley, F; Kelly, M S; Lehto, M H; Reeve, J; Thompson, L F; Affholderbach, K; Böhrer, A; Brandt, S; Cowan, G D; Grupen, Claus; Saraiva, P; Smolik, L; Stephan, F; Apollonio, M; Bosisio, L; Della Marina, R; Giannini, G; Gobbo, B; Musolino, G; Rothberg, J E; Wasserbaech, S R; Armstrong, S R; Charles, E; Elmer, P; Ferguson, D P S; Gao, Y; González, S; Greening, T C; Hayes, O J; Hu, H; Jin, S; McNamara, P A; Nachtman, J M; Nielsen, J; Orejudos, W; Pan, Y B; Saadi, Y; Scott, I J; Walsh, J; Wu Sau Lan; Wu, X; Zobernig, G

    1998-01-01

    An analysis based on 124000 selected tau pairs recorded by the ALEPH detector at LEP provides the vector (V) and axial-vector (A) spectral functions of hadronic tau decays together with their total widths. This allows the evaluation of finite energy chiral sum rules that are weighted integrals over the (V-A) spectral functions. In addition, a precise measurement of alpha_s along with a determination of nonperturbative contributions at the tau mass scale is performed. The experimentally and theoretically most robust determination of alpha_s(M_tau^2) is obtained from the (V+A) fit that yields alpha_s(M_tau^2) = 0.334 +/- 0.022 giving alpha_s(M_Z^2) = 0.1202 +/- 0.0027 after the extrapolation to the mass of the Z boson. The approach of the Operator Product Expansion (OPE) is tested experimentally studying the evolution of the tau hadronic widths to masses smaller than the tau mass.

  3. Recoil-alpha-fission and recoil-alpha-alpha-fission events observed in the reaction Ca-48 + Am-243

    NARCIS (Netherlands)

    Forsberg, U.; Rudolph, D.; Andersson, L. -L.; Nitto, A. Di; Düllmann, Ch E.; Gates, J. M.; Golubev, P.; Gregorich, K. E.; Gross, C. J.; Herzberg, R. -D.; Hessberger, F. P.; Khuyagbaatar, J.; Kratz, J. V.; Rykaczewski, K.; Sarmiento, L. G.; Schädel, M.; Yakushev, A.; Åberg, S.; Ackermann, D.; Block, M.; Brand, H.; Carlsson, B. G.; Cox, D.; Derkx, X.; Dobaczewski, J.; Eberhardt, K.; Even, J.; Fahlander, C.; Gerl, J.; Jäger, E.; Kindler, B.; Krier, J.; Kojouharov, I.; Kurz, N.; Lommel, B.; Mistry, A.; Mokry, C.; Nazarewicz, W.; Nitsche, H.; Omtvedt, J. P.; Papadakis, P.; Ragnarsson, I.; Runke, J.; Schaffner, H.; Schausten, B.; Shi, Y.; Thörle-Pospiech, P.; Torres, T.; Traut, T.; Trautmann, N.; Türler, A.; Ward, A.; Ward, D. E.; Wiehl, N.

    2016-01-01

    Products of the fusion-evaporation reaction Ca-48 + Am-243 were studied with the TASISpec set-up at the gas-filled separator TASCA at the GSI Helmholtzzentrum f\\"ur Schwerionenforschung. Amongst the detected thirty correlated alpha-decay chains associated with the production of element Z=115, two

  4. Side-chain-anchored N(alpha)-Fmoc-Tyr-OPfp for bidirectional solid-phase synthesis

    DEFF Research Database (Denmark)

    Olsen, Christian A; Jørgensen, Malene; Hansen, Steen H

    2005-01-01

    [reaction: see text] A mild resin-immobilization strategy employing a readily prepared trityl bromide resin for anchoring building blocks via a phenol group has been developed. With N(alpha)-Fmoc-Tyr-OPfp as a starter building block, it was possible to prepare asymmetrically substituted hybrids o...

  5. Alpha-chain states in 4N-nuclei from 20Ne to 32S

    International Nuclear Information System (INIS)

    Merchant, A.C.; Rae, W.D.M.

    1992-01-01

    A 6α-chain state has recently been discovered in 24 Mg which is some 16--17 MeV above the 6α-breakup threshold and yet paradoxically only 4--5 MeV wide. This surprising discovery raises the question of the possible existence of Nα-chain states in other 4N-nuclei. The excitation energy of this 6α-chain state is very close to the value predicted by the Bloch-Brink cluster model. Therefore, to aid the experimental search for similar states in other nuclei, we present here predictions of the excitation energies of the Nα-chain state bandheads in the 4N-nuclei from 20 Ne to 32 S obtained using the Bloch-Brink cranked cluster model with the Brink-Boeker effective interaction and free variation of all parameters

  6. Finite size vertex correction to the strong decay of eta sub c and chi sub c states and a determination of alpha sub s (m sub c)

    CERN Document Server

    Ping Rong Gang; Zou Bing Song

    2002-01-01

    The authors calculate the correction to the two-gluon decay width due to the finite extension of the vertex function. The authors obtain the corrected factor to the zero-range vertex gamma = 1.32, gamma = 1.45, gamma= 1.26 for eta sub c , chi sub c sub 0 , and chi sub c sub 2 , respectively. With the decay width GAMMA(eta sub c->2 g) the authors extract the value alpha sub s (m sub c) 0.28 +- 0.05 which agrees with that calculated from the same correction to the process GAMMA(J/psi -> 3 g). This correction to the process GAMMA(eta sub c -> 2 g) is not as large as that to the process GAMMA(J/psi -> 3 g)

  7. Search for right-handed currents in the decay chain of K+ → μ+νμ, μ+ → e+νeν-barμ

    International Nuclear Information System (INIS)

    Aoki, M.; Yamazaki, T.; Imazato, J.

    1993-12-01

    The asymmetry of positrons in the K + → μ + ν, μ + → e + ν e ν-bar μ decay chain was measured in a search for right-handed weak currents in ΔS = 1 semi-leptonic decay. High-intensity low-background monoenergetic polarized muons of 236 MeV/c momentum resulting from kaon decay at rest were directly extracted from a primary production target which was hit by a proton beam of the KEK 12-GeV proton synchrotron. Muons were stopped in a pure-aluminum plate, and the energy-integrated asymmetry of the decay positrons with respect to the incoming muon direction was determined to high precision. The observed asymmetry yielded ξP μ = -0.9996 ± 0.0030(stat) ± 0.0048(sys). This result revealed no evidence of right-handed currents in this kaon-decay chain, and set a stringent bound on the mass of the right-handed weak boson. (author) 52 refs

  8. Theoretical predictions for α -decay chains of 118 290 -298Og isotopes using a finite-range nucleon-nucleon interaction

    Science.gov (United States)

    Ismail, M.; Adel, A.

    2018-04-01

    The α -decay half-lives of the recently synthesized superheavy nuclei (SHN) are investigated by employing the density dependent cluster model. A realistic nucleon-nucleon (NN ) interaction with a finite-range exchange part is used to calculate the microscopic α -nucleus potential in the well-established double-folding model. The calculated potential is then implemented to find both the assault frequency and the penetration probability of the α particle by means of the Wentzel-Kramers-Brillouin (WKB) approximation in combination with the Bohr-Sommerfeld quantization condition. The calculated values of α -decay half-lives of the recently synthesized Og isotopes and its decay products are in good agreement with the experimental data. Moreover, the calculated values of α -decay half-lives have been compared with those values evaluated using other theoretical models, and it was found that our theoretical values match well with their counterparts. The competition between α decay and spontaneous fission is investigated and predictions for possible decay modes for the unknown nuclei 118 290 -298Og are presented. We studied the behavior of the α -decay half-lives of Og isotopes and their decay products as a function of the mass number of the parent nuclei. We found that the behavior of the curves is governed by proton and neutron magic numbers found from previous studies. The proton numbers Z =114 , 116, 108, 106 and the neutron numbers N =172 , 164, 162, 158 show some magic character. We hope that the theoretical prediction of α -decay chains provides a new perspective to experimentalists.

  9. Single base mutation in the pro. alpha. 2(I) collagen gene that causes efficient splicing of RNA from exon 27 to exon 29 and synthesis of a shortened but in-frame pro. alpha. 2(I) chain

    Energy Technology Data Exchange (ETDEWEB)

    Tromp, G.; Prockop, D.J. (Thomas Jefferson Univ., Philadelphia, PA (USA))

    1988-07-01

    Previous observations demonstrated that a lethal variant of osteogenesis imperfecta had two altered alleles for pro{alpha}2(I) chains of type I procollagen. One mutation produced a nonfunctioning allele in that there was synthesis of mRNA but no detectable synthesis of pro{alpha}2(I) chains from the allele. The mutation in the other allele caused synthesis of shortened pro{alpha}2(I) chains that lacked most or all of the 18 amino acids encoded by exon 28. Subclones of the pro{alpha}2(I) gene were prepared from the proband's DNA and the DNA sequence was determined for a 582-base-pair (bp) region that extended from the last 30 bp of intervening sequence 26 to the first 26 bp of intervening sequence 29. Data from six independent subclones demonstrated that all had the same sequence as a previously isolated normal clone for the pro{alpha}2(I) gene except that four subclones had a single base mutation at the 3{prime} end of intervening sequence 27. The mutation was a substitution of guanine for adenine that changed the universal consensus sequence for the 3{prime} splicing site of RNA from -AG- to -GG-. S1 nuclease experiments demonstrated that about half the pro{alpha}2(I) mRNA in the proband's fibroblasts was abnormally spliced and that the major species of abnormal pro{alpha}2(I) mRNA was completely spliced from the last codon of exon 27 to the first codon of exon 29. The mutation is apparently unique among RNA splicing mutations of mammalian systems in producing a shortened polypeptide chain that is in-frame in terms of coding sequences, that is used in the subunit assembly of a protein, and that contributes to a lethal phenotype.

  10. Synthetic peptide antigens derived from long-chain alpha-neurotoxins: Immunogenicity effect against elapid venoms.

    Science.gov (United States)

    de la Rosa, Guillermo; Pastor, Nina; Alagón, Alejandro; Corzo, Gerardo

    2017-02-01

    Three-finger toxins (3FTXs), especially α-neurotoxins, are the most poorly neutralized elapid snake toxins by current antivenoms. In this work, the conserved structural similarity and motif arrangements of long-chain α-neurotoxins led us to design peptides with consensus sequences. Eight long-chain α-neurotoxins (also known as Type II) were used to generate a consensus sequence from which two peptides were chemically synthesized, LCP1 and LCP2. Rabbit sera raised against them were able to generate partially-neutralizing antibodies, which delayed mice mortality in neutralization assays against Naja haje, Dendrospis polylepis and Ophiophagus hannah venoms. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. On the calculation of {sup 3}J{sub {alpha}{beta}}-coupling constants for side chains in proteins

    Energy Technology Data Exchange (ETDEWEB)

    Steiner, Denise [Swiss Federal Institute of Technology, Laboratory of Physical Chemistry, ETH (Switzerland); Allison, Jane R. [Massey University Albany, Centre for Theoretical Chemistry and Physics, Institute for Natural Sciences (New Zealand); Eichenberger, Andreas P.; Gunsteren, Wilfred F. van, E-mail: wfvgn@igc.phys.chem.ethz.ch [Swiss Federal Institute of Technology, Laboratory of Physical Chemistry, ETH (Switzerland)

    2012-07-15

    Structural knowledge about proteins is mainly derived from values of observables, measurable in NMR spectroscopic or X-ray diffraction experiments, i.e. absorbed or scattered intensities, through theoretically derived relationships between structural quantities such as atom positions or torsional angles on the one hand and observable quantities such as squared structure factor amplitudes, NOE intensities or {sup 3}J-coupling constants on the other. The standardly used relation connecting {sup 3}J-couplings to torsional angles is the Karplus relation, which is used in protein structure refinement as well as in the evaluation of simulated properties of proteins. The accuracy of the simple and generalised Karplus relations is investigated using side-chain structural and {sup 3}J{sub {alpha}{beta}}-coupling data for three different proteins, Plastocyanin, Lysozyme, and FKBP, for which such data are available. The results show that the widely used Karplus relations are only a rough estimate for the relation between {sup 3}J{sub {alpha}{beta}}-couplings and the corresponding {chi}{sub 1}-angle in proteins.

  12. alpha-decay spectroscopy of light odd-odd Bi isotopes - II sup 1 sup 8 sup 6 Bi and the new nuclide sup 1 sup 8 sup 4 Bi

    CERN Document Server

    Andreyev, A N; Ackermann, D; Münzenberg, G; Hessberger, F P; Hofmann, S; Kojouharov, I; Kindler, B; Lommel, B; Huyse, M; Vel, K V D; Duppen, P V; Heyde, Kris L G

    2003-01-01

    Alpha-decay of the new nuclide sup 1 sup 8 sup 4 Bi has been studied in the complete-fusion reaction sup 9 sup 3 Nb( sup 9 sup 4 Mo, 3n) sup 1 sup 8 sup 4 Bi at the velocity filter SHIP. The evaporation residues were separated in-flight and subsequently identified on the basis of recoil-alpha, recoil-alpha-gamma analysis and excitation functions measurements. Two alpha-decaying isomeric states in sup 1 sup 8 sup 4 Bi with half-life values of 13(2) ms and 6.6(1.5) ms were identified. The alpha-branching ratio of sup 1 sup 8 sup 0 Tl was deduced for the first time as b subalpha = (2-12)%. Improved data on the fine-structure alpha-decay of sup 1 sup 8 sup 6 Bi were obtained in the sup 9 sup 3 Nb( sup 9 sup 5 Mo, 2n) sup 1 sup 8 sup 6 Bi reaction. A similarity of the decay energies and half-life values of sup 1 sup 8 sup 4 sup , sup 1 sup 8 sup 6 Bi is pointed out and a possible explanation for this effect is suggested.

  13. Structural requirement of carboxyl-terminal globular domains of laminin alpha 3 chain for promotion of rapid cell adhesion and migration by laminin-5.

    Science.gov (United States)

    Hirosaki, T; Mizushima, H; Tsubota, Y; Moriyama, K; Miyazaki, K

    2000-07-21

    The basement membrane protein laminin-5, a heterotrimer of laminin alpha3, beta3, and gamma2 chains, potently promotes cellular adhesion and motility. It has been supposed that the carboxyl-terminal globular region of the alpha3 chain consisting of five distinct domains (G1 to G5) is important for its interaction with integrins. To clarify the function of each G domain, we transfected cDNAs for the full-length (wild type (WT)) and five deletion derivatives (DeltaGs) of the alpha3 chain into human fibrosarcoma cell line HT1080, which expressed and secreted the laminin beta3 and gamma2 chains but not the alpha3 chain. The transfectants with the alpha3 chain cDNAs lacking G5 (DeltaG(5)), G4-5 (DeltaG(4-5)), G3-5 (DeltaG(3-5)), and G2-5 (DeltaG(2-5)) secreted laminin-5 variants at levels comparable to that with WT cDNA. However, the transfectant with the cDNA without any G domains (DeltaG(1-5)) secreted little laminin-5, suggesting that the G domains are essential for the efficient assembly and secretion of the heterotrimer alpha3beta3gamma2. The transfectants with WT, DeltaG(5), and DeltaG(4-5) cDNAs survived in serum-free medium longer than those with DeltaG(3-5), DeltaG(2-5), and DeltaG(1-5) cDNAs. The transfectants with WT, DeltaG(5), and DeltaG(4-5) cDNAs secreted apparently the same size of laminin-5, which lacked G4 and G5 due to proteolytic cleavage between G3 and G4, and these laminin-5 forms potently promoted integrin alpha(3)beta(1)-dependent cell adhesion and migration. However, the laminin-5 forms of DeltaG(3-5) and DeltaG(2-5) hardly promoted the cell adhesion and motility. These findings demonstrate that the G3 domain, but not the G4 and G5 domains, of the alpha3 chain is essential for the potent promotion of cell adhesion and motility by laminin-5.

  14. "Alpha decays" of Be-10(Lambda) and B-10(Lambda) hypernuclei: Phenomenological analysis and role of nuclear structure

    Czech Academy of Sciences Publication Activity Database

    Majling, Lubomír; Kuzmin, V. A.; Tetereva, T. V.

    2004-01-01

    Roč. 67, č. 10 (2004), s. 1804-1809 ISSN 1063-7788 R&D Projects: GA ČR GA202/02/0930 Institutional research plan: CEZ:AV0Z1048901 Keywords : nonmesonic weak decay * Lambda-hypernuclei * shell Subject RIV: BE - Theoretical Physics Impact factor: 0.781, year: 2004

  15. The human rhabdomyosarcoma cell line A204 lays down a highly insoluble matrix composed mainly of alpha 1 type-XI and alpha 2 type-V collagen chains.

    Science.gov (United States)

    Kleman, J P; Hartmann, D J; Ramirez, F; van der Rest, M

    1992-11-15

    The biosynthesis of collagen by the A204 cell line was examined using polyclonal antibodies raised against collagen type V and type XI. The study of the pepsin-digested collagen showed that it is composed mainly of alpha 1(XI) and alpha 2(V) collagen chains in an apparent 2:1 ratio, suggesting the formation of heterotypic molecules [alpha 1(XI)]2 alpha 2(V). The existence of this chain stoichiometry was further demonstrated by immunoprecipitation of the molecule with an antibody recognizing alpha 2(V) but not alpha 1(XI) collagen chains. Electron microscopy analyses of 24-h cultures showed that this matrix is composed of thin fibrils, that can be decorated with immunogold-labelled anti-(type-V collagen) IgG, but not with anti-(type-XI collagen) IgG. The collagen matrix laid down by A204 cells is highly insoluble. In the presence of beta-aminopropionitrile, an inhibitor of lysyl oxidase, only a small proportion of intact collagen could be extracted without proteolytic treatment. Immunoblotting of intact medium collagen from cultures performed in the presence of beta-aminopropionitrile showed four distinct bands with each antibody. The migration of the bands, stained with anti-(type-V collagen) IgG, had apparent molecular masses of 127, 149, 161 and 198 kDa (compared to globular standards) while the bands stained with anti-(type-XI collagen) IgG had apparent masses of 145, 182, 207 and 225 kDa. These data indicate that type-V and type-XI collagen chains can assemble in heterotypic isoforms. In this system, the synthesized isoforms are able to aggregate into a highly cohesive matrix and they undergo a proteolytic processing closely similar to that of other fibrillar collagens.

  16. Solute transport through fractured rock: Radial diffusion into the rock matrix with several geological layers for an arbitrary length decay chain

    Science.gov (United States)

    Mahmoudzadeh, Batoul; Liu, Longcheng; Moreno, Luis; Neretnieks, Ivars

    2016-05-01

    The paper presents a model development to derive a semi-analytical solution to describe reactive solute transport through a single channel in a fracture with cylindrical geometry. The model accounts for advection through the channel, radial diffusion into the adjacent heterogeneous rock matrix comprising different geological layers, adsorption on both the channel surface, and the geological layers of the rock matrix and radioactive decay chain. Not only an arbitrary-length decay chain, but also as many number of the rock matrix layers with different properties as observed in the field can be handled. The solution, which is analytical in the Laplace domain, is transformed back to the time domain numerically e.g. by use of de Hoog algorithm. The solution is verified against experimental data and analytical solutions of limiting cases of solute transport through porous media. More importantly, the relative importance and contribution of different processes on solute transport retardation in fractured rocks are investigated by simulating several cases of varying complexity. The simulation results are compared with those obtained from rectangular model with linear matrix diffusion. It is found that the impact of channel geometry on breakthrough curves increases markedly as the transport distance along the flow channel and away into the rock matrix increase. The effect of geometry is more pronounced for transport of a decay chain when the rock matrix consists of a porous altered layer.

  17. Expression of the Alpha8 Integrin Chain Facilitates Phagocytosis by Renal Mesangial Cells

    Directory of Open Access Journals (Sweden)

    Ines Marek

    2018-03-01

    Full Text Available Background/Aims: Healing of mesangioproliferative glomerulonephritis involves degradation of excess extracellular matrix, resolution of hypercellularity by apoptosis and phagocytosis of apoptotic cells. Integrin receptors participate in the regulation of phagocytosis. In mice deficient for alpha8 integrin (Itga8-/- healing of glomerulonephritis is delayed. As Itga8 is abundant in mesangial cells (MC which are non-professional phagocytes, we hypothesized that Itga8 facilitates phagocytosis of apoptotic cells and matrix components by MC. Methods: MC were isolated from wild type (WT and Itga8-/- mice. Latex beads were coated with matrix components. Apoptosis was induced by cisplatin in macrophages and in DiI-stained MC. After coincubation of latex beads or apoptotic cells with MC, the phagocytosis rate was detected in WT and Itga8-/- MC via fluorescence microscopy and FACS analysis. Results: Itga8-/- MC showed reduced phagocytosis of matrix-coated beads and apoptotic cells compared to WT MC. Reduction of stress fibers was observed in Itga8-/- compared to WT MC. Inhibition of cytoskeletal reorganization by inhibition of Rac1 or ROCK during phagocytosis significantly decreased the rate of phagocytosis by WT MC but not by Itga8-/- MC. Conclusion: The expression of Itga8 facilitates phagocytosis in MC, likely mediated by Itga8-cytoskeleton interactions. An impairment of MC phagocytosis might thus contribute to a delayed glomerular regeneration in Itga8-/- mice.

  18. Stereochemistry of the peroxisomal branched-chain fatty acid alpha- and beta-oxidation systems in patients suffering from different peroxisomal disorders

    NARCIS (Netherlands)

    Ferdinandusse, S.; Rusch, H.; van Lint, A. E. M.; Dacremont, G.; Wanders, R. J. A.; Vreken, P.

    2002-01-01

    Phytanic acid (3,7,11,15-tetramethylhexadecanoic acid) is a branched-chain fatty acid derived from dietary sources and broken down in the peroxisome to pristanic acid (2,6,10,14-tetramethylpentadecanoic acid) via alpha-oxidation. Pristanic acid then undergoes beta-oxidation in peroxisomes. Phytanic

  19. Updated model for radionuclide transport in the near-surface till at Forsmark - Implementation of decay chains and sensitivity analyses

    Energy Technology Data Exchange (ETDEWEB)

    Pique, Angels; Pekala, Marek; Molinero, Jorge; Duro, Lara; Trinchero, Paolo; Vries, Luis Manuel de [Amphos 21 Consulting S.L., Barcelona (Spain)

    2013-02-15

    tendency to overestimate radionuclide concentrations at the discharge zone). Specifically, examination of the modelling results indicates that: 1. The implementation of the revised till stratigraphy has an overall small impact on the modelling results: despite distinctly different groundwater flow patterns, tracer arrival at the discharge zone is similar between the previous and current till models. 2. Of the radionuclides studied only {sup 226}Ra is significantly affected by radioactive chain decay dynamics. 3. The values of geochemical parameters used in the Base Case reactive transport calculations produce conservative results. 4. The model is largely insensitive to significant variations in dispersivity of the till and an alternative definition of the shallow groundwater inflow, although the elimination of vertical stratification in hydraulic conductivity has the effect to speed up radionuclide transport. 5. Over saturation with barite is not reached under any of the considered scenarios hence Ra coprecipitation with barite does not contribute to {sup 226}Ra retardation under the assumptions of the model. In contrast, Sr co-precipitation with calcite is an important retention mechanism for {sup 90}Sr.

  20. Measurement of the absolute activity of alpha or beta emitters by measuring product nuclei (daughter) activity increase or by studing its radioactive decay

    International Nuclear Information System (INIS)

    Campos, L.C. de.

    1981-01-01

    A new method for determining absolute activity of alpha or beta emitters by measuring daughter product radioactive decay is presented. The separation method of UX from hexahydrated uranyl nitrate UO 2 (NO 3 ) 2 6H 2 O based on its dissolution in ethyl ether is described and the accuracy of this method is shown. The factors which accuate on total efficiency of a Geiger Mueller detector for beta particles are determined. The possibility to determine the mass of precursor element by daughter nuclei activity is shown. The results are compared with the one obtained by direct measurement of the mass (or number of atoms) of precursor radioactive substance and with theoretical values calculated for isotopes in secular equilibrium. (Author) [pt

  1. Theoretical predictions on the decay properties of superheavy nuclei Z = 123 in the region 297 ≤ A ≤ 307

    Energy Technology Data Exchange (ETDEWEB)

    Santhosh, K.P.; Nithya, C. [Kannur University, School of Pure and Applied Physics, Payyanur, Kerala (India)

    2016-12-15

    Decay modes of isotopes of the superheavy element Z = 123 within the range 297 ≤ A ≤ 307 have been studied by comparing the alpha decay half-lives with the spontaneous fission half-lives. Three different mass tables were used for the calculation of the alpha decay energy. A close study of alpha decay half-lives within the range 297 ≤ A ≤ 307 has been performed using the Coulomb and proximity potential model for deformed nuclei (CPPMDN). The alpha half-lives calculated using CPPMDN are in harmony with the values obtained by the Viola-Seaborg systematic, the universal curve of Poenaru et al., and the analytical formula of Royer. Spontaneous fission half-lives are evaluated using the new shell-effect-dependent formula proposed by Santhosh et al., and the semi-empirical formula of Xu et al. Through our study it is seen that the isotopes {sup 300-303}123 exhibit 8α chains and the isotopes {sup 304-307}123 exhibit 5α chains with half-lives in a measurable range. Clearly the isotopes of Z = 123 within the range 300 ≤ A ≤ 307 will decay through alpha emission followed by spontaneous fission and thus can be predicted as synthesized and detected in laboratory via alpha decay. Since the predictions on decay modes of isotopes of the superheavy element Z = 123 is done for the first time it is hoped that the study will open up new areas in experimental investigations. (orig.)

  2. A control volume scheme for three-dimensional transport: buffer and matrix effect on a decay chain transport in the repository

    International Nuclear Information System (INIS)

    Lee, Y. M.; Hwang, Y. S.; Kim, S. G.; Kang, C. H.

    2002-01-01

    Using a three-dimensional numerical code, B3R developed for nuclide transport of an arbitrary length of decay chain in the buffer between the canister and adjacent rock in a high-level radioactive waste repository by adopting a finite difference method utilizing the control-volume scheme, some illustrative calculations have been done. A linear sorption isotherm, nuclide transport due to diffusion in the buffer and the rock matrix, and advection and dispersion along thin rigid parallel fractures existing in a saturated porous rock matrix as well as diffusion through the fracture wall into the matrix is assumed. In such kind of repository, buffer and rock matrix are known to be important physico-chemical barriers in nuclide retardation. To show effects of buffer and rock matrix on nuclide transport in HLW repository and also to demonstrate usefulness of B3R, several cases of breakthrough curves as well as three-dimensional plots of concentration isopleths associated with these two barriers are introduced for a typical case of decay chain of 234 U→ 230 Th→ 226 Ra, which is the most important chain as far as the human environment is concerned

  3. Predictions on the modes of decay of odd Z superheavy isotopes within the range 105 ≤ Z ≤ 135

    Science.gov (United States)

    Santhosh, K. P.; Nithya, C.

    2018-05-01

    The decay modes of 1051 odd Z superheavy nuclei within the range 105 ≤ Z ≤ 135, and their daughter nuclei are studied by comparing the alpha decay half-lives with the spontaneous fission half-lives. The alpha decay half-lives are calculated using the Coulomb and proximity potential model for deformed nuclei (CPPMDN) proposed by Santhosh et al. (2011) and the spontaneous fission half-lives are obtained with the shell-effect dependent formula of Santhosh et al. (Santhosh and Nithya, 2016). For a theoretical comparison, the alpha decay half-lives are also computed with the Coulomb and proximity potential model (CPPM), Viola-Seaborg-Sobiczewski semi-empirical relation (VSS), Universal curve of Poenaru et al. (UNIV), the analytical formula of Royer, and the Universal decay law of Qi et al. (UDL). The predicted decay modes and half-lives were compared with the available experimental results. The proton and neutron separation energies are calculated to identify those nuclei, which decay through proton and neutron emission. From the entire study of odd Z superheavy elements, it is seen that among 1051 nuclei, 233 nuclei exhibit proton emission and 18 nuclei exhibit neutron emission. 56 nuclei are stable against alpha decay with negative Q value for the decay. 92 nuclei show alpha decay followed by spontaneous fission and 9 nuclei show alpha decay followed by proton emission. 39 nuclei decay through full alpha chain and 595 nuclei decay through spontaneous fission. We hope that the study will be very useful for the future experimental investigations in this field.

  4. Expression of triplicated and quadruplicated alpha globin genes in sheep.

    Science.gov (United States)

    Vestri, R; Pieragostini, E; Yang, F; di Gregorio, P; Rando, A; Masina, P

    1991-01-01

    In the sheep alpha alpha alpha globin gene haplotype, the three genes display from the 5' to the 3' end the percentage efficiencies of about 30:14:6, as indicated by the amounts of the three types of alpha chain produced in the alpha alpha alpha/alpha alpha alpha homozygotes. The 3' gene in the alpha alpha alpha alpha haplotype appears to have an efficiency around 1%, as suggested by analysis of one quadruple alpha homozygote. Moreover, the total outputs of the alpha alpha alpha as well as of the alpha alpha alpha alpha haplotypes do not substantially differ from that of the common alpha alpha haplotype.

  5. A polymorphic variant in the human electron transfer flavoprotein alpha-chain (alpha-T171) displays decreased thermal stability and is overrepresented in very-long-chain acyl-CoA dehydrogenase-deficient patients with mild childhood presentation

    DEFF Research Database (Denmark)

    Bross, P; Pedersen, P; Winter, V

    1999-01-01

    The consequences of two amino acid polymorphisms of human electron transfer flavoprotein (alpha-T/I171 in the alpha-subunit and beta-M/T154 in the beta-subunit) on the thermal stability of the enzyme are described. The alpha-T171 variant displayed a significantly decreased thermal stability, wher....... This is compatible with a negative modulating effect of the less-stable alpha-T171 ETF variant in this group of VLCAD patients that harbor missense mutations in at least one allele and therefore potentially display residual levels of VLCAD enzyme activity....

  6. Macro- and micromechanical remodelling in the fish atrium is associated with regulation of collagen 1 alpha 3 chain expression.

    Science.gov (United States)

    Keen, Adam N; Fenna, Andrew J; McConnell, James C; Sherratt, Michael J; Gardner, Peter; Shiels, Holly A

    2018-03-28

    Numerous pathologies lead to remodelling of the mammalian ventricle, often associated with fibrosis. Recent work in fish has shown that fibrotic remodelling of the ventricle is 'reversible', changing seasonally as temperature-induced changes in blood viscosity alter haemodynamic load on the heart. The atrial response to varying haemodynamic load is less understood in mammals and completely unexplored in non-mammalian vertebrates. To investigate atrial remodelling, rainbow trout were chronically cooled (from 10 ± 1 to 5 ± 1 °C) and chronically warmed (from 10 ± 1 to 18 ± 1 °C) for a minimum of 8 weeks. We assessed the functional effects on compliance using ex vivo heart preparations and atomic force microscopy nano-indentation and found chronic cold increased passive stiffness of the whole atrium and micromechanical stiffness of tissue sections. We then performed histological, biochemical and molecular assays to probe the mechanisms underlying functional remodelling of the atrial tissue. We found cooling resulted in collagen deposition which was associated with an upregulation of collagen-promoting genes, including the fish-specific collagen I alpha 3 chain, and a reduction in gelatinase activity of collagen-degrading matrix metalloproteinases (MMPs). Finally, we found that cooling reduced mRNA expression of cardiac growth factors and hypertrophic markers. Following long-term warming, there was an opposing response to that seen with cooling; however, these changes were more moderate. Our findings suggest that chronic cooling causes atrial dilation and increased myocardial stiffness in trout atria analogous to pathological states defined by changes in preload or afterload of the mammalian atria. The reversal of this phenotype following chronic warming is particularly interesting as it suggests that typically pathological features of mammalian atrial remodelling may oscillate seasonally in the fish, revealing a more dynamic and plastic atrial

  7. Anchor residue motifs of HLA class-I-binding peptides analyzed by the direct binding of synthetic peptides to HLA class I alpha chains.

    Science.gov (United States)

    Fruci, D; Rovero, P; Falasca, G; Chersi, A; Sorrentino, R; Butler, R; Tanigaki, N; Tosi, R

    1993-11-01

    The binding characteristics of the primary anchor residue motifs reported for HLA-A2 (A*0201, A*0205) and HLA-B27 (B*2705) alleles were investigated by a direct binding assay of the pertinent synthetic peptides to HLA class I alpha chains derived from a panel of HLA homozygous B-cell lines of various HLA phenotypes, including four A2 subtypes. The assay is based on a serologic detection of the conformational change of HLA class I alpha chains induced by binding to specific peptides in the presence of beta 2m. It is applicable to test a large number of HLA allelic products and synthetic peptides. Assay data confirmed the high allele specificity of the anchor residue motifs tested, but also revealed the intra- and interlocus cross-reactivity of these motifs. In the case of A2 anchor motifs, not only a broad cross-reactivity within the A2 subgroup, but also cross-reactivities with A24, A26, A28, and A29 were observed. With B27 anchor motifs, an interlocus cross-reactivity with A3 and A31 was seen. Several peptides, even though they carried A2 or B27 major anchor residue motifs, failed to bind to the relevant alpha chains, suggesting that the presence of a primary anchor residue motif is necessary for HLA class-I-peptide binding but is not by itself sufficient to guarantee binding.

  8. Use of MICRAS code on the evaluation of the maximum radionuclides concentrations due to transport/migration of decay chain in groundwaters

    International Nuclear Information System (INIS)

    Aquino Branco, O.E. de

    1995-01-01

    This paper presents a methodology for the evaluation of the maximum radionuclides concentrations in groundwaters, due to the transport/migration of decay chains. Analytical solution of the equations system is difficult, even if only three elements of the decay chain are considered. Therefore, a numerical solution is most convenient. An application of the MICRAS code, developed to assess maximum concentrations of each radionuclide, starting with the initial concentrations, is presented. The maximum concentration profile for 226 Ra, calculated using MICRAS, is compared with the results obtained through an analytical and a numerical model. The fitness of results is considered good. Simplified models, like the one represented by the application of MICRAS, are largely employed in the section in the selection and characterization of sites for radioactive wastes repositories and in studies of safety evaluation for the same purpose. A detailed analysis of the transport/migration of contaminants in aquifers requires a large quantify of data from the site and from the installation as well, which makes this analysis expensive and inviable during the preliminary phases of the studies. (author). 6 refs, 1 fig, 1 tab

  9. Transport of a Two-Member Decay Chain of Radionuclides Through a Discrete Fracture in a Porous Rock Matrix in the Presence of Colloids

    International Nuclear Information System (INIS)

    Tien, N.-C.; Li Shihhai

    2002-01-01

    Many physical and chemical processes dominate the transport of radionuclides in groundwater. Among these processes, the decay chain process of radionuclides was frequently disregarded in previous research. However, the daughter products may travel much farther than their parents along the fracture. Therefore, some models neglecting the effect of the decay chain may underestimate the transport radionuclide concentration in geological media. The transport of radionuclides in groundwater is also controlled by colloidal particles. The radionuclides may be enhanced or retarded by the colloids, according to the mobility of these colloidal particles. This work describes a novel model of the transport of a two-member decay chain of radionuclides through a discrete fracture in a porous rock matrix in the presence of colloids. The model addresses the following processes: (a) advective transport in the fracture, (b) mechanical dispersion and molecular diffusion along the fracture, (c) molecular diffusion from the fracture to the rock matrix, (d) adsorption onto the fracture wall, (e) adsorption in the rock matrix, and (f) radioactive decay. Furthermore, colloids are assumed to be excluded from the matrix pores because of their size. A fully developed concentration profile system with nonreactive colloids is used to understand the effect of colloidal sizes by using hydrodynamic chromatography. The external forces acting on the colloid surface, such as the inertial, the van der Waals attractive force, the double layer force, and the gravitational force are accounted for. The parameters, the average velocity of the colloid, the dispersion coefficient of the colloid, and the distribution coefficient of radionuclides with colloids are modified according to the colloidal size. The transport equations for the parent radionuclides are solved analytically using the Laplace transformation and inversion method. However, for the transformed solution of the daughter products along the

  10. Development of a computational algorithm for the linearization of decay and transmutation chains; Desarrollo de un algoritmo computacional para la linealizacion de cadenas de decaimiento y transmutacion

    Energy Technology Data Exchange (ETDEWEB)

    Cruz L, C. A.; Francois L, J. L., E-mail: cacl@ier.unam.mx [UNAM, Facultad de Ingenieria, Departamento de Sistemas Energeticos, Paseo Cuauhnahuac 8532, Col. Progreso, 62550 Jiutepec, Morelos (Mexico)

    2017-09-15

    One of the most used methodologies to solve Bate man equations, in the problem of burning, is the Tta (Transmutation Trajectory Analysis) method. In this method, a network of decays is broken down into linear elements known as trajectories, through a process known as linearization. In this work an alternative algorithm is shown to find and construct these trajectories, which considers three aspects of linearization: the information -a priori- about the elements that make up decay and transmutation network, the use of a new notation, and in the functions for the treatment of text strings (which are common in most programming languages). One of the main advantages of the algorithm is that can condense the information of a decay and transmutation network into only two vectors. From these is possible to determine how many linear chains can be extracted from the network and even their length (in the case they are not cyclical). Unlike the Deep First Search method, which is widely used for the linearization process, the method proposed in the present work does not have a backward routine and instead occupies a process of compilation, since completes fragments chain instead of going back to the beginning of the trajectories. The developed algorithm can be applied in a general way to the information search and to the linearization of the computational data structures known as trees. It can also be applied to engineering problems where one seeks to calculate the concentration of some substance as a function of time, starting from linear differential equations of balance. (Author)

  11. Synchronous Measurements of Alpha-Decay of 239-Pu Carried out at North Pole, Antarctic, and in Puschino Confirm that the Shapes of the Respective Histograms Depend on the Diurnal Rotation of the Earth and on the Direction of the Alpha-Particle Beam

    Directory of Open Access Journals (Sweden)

    Shnoll S. E.

    2012-07-01

    Full Text Available Dependence of histogram shapes from Earth diurnal rotation, and from direction of alpha-particles issue at 239 Pu radioactive decay is confirmed by simultaneous measure- ments of fluctuation amplitude spectra — shapes of corresponding histograms. The measurements were made with various methods and in different places: at the North Pole, in Antarctic (Novolazarevskaya station, and in Puschino.

  12. Measurement of the parity-violating asymmetry parameter $\\alpha_b$ and the helicity amplitudes for the decay $\\Lambda_b^0\\to J/\\psi\\Lambda^0$ with the ATLAS detector

    CERN Document Server

    Aad, Georges; Abbott, Brad; Abdallah, Jalal; Abdel Khalek, Samah; Abdinov, Ovsat; Aben, Rosemarie; Abi, Babak; Abolins, Maris; AbouZeid, Ossama; Abramowicz, Halina; Abreu, Henso; Abulaiti, Yiming; Acharya, Bobby Samir; Adamczyk, Leszek; Adams, David; Adelman, Jahred; Adomeit, Stefanie; Adye, Tim; Agatonovic-Jovin, Tatjana; Aguilar-Saavedra, Juan Antonio; Agustoni, Marco; Ahlen, Steven; Ahmad, Ashfaq; Ahmadov, Faig; Aielli, Giulio; Åkesson, Torsten Paul Ake; Akimoto, Ginga; Akimov, Andrei; Albert, Justin; Albrand, Solveig; Alconada Verzini, Maria Josefina; Aleksa, Martin; Aleksandrov, Igor; Alexa, Calin; Alexander, Gideon; Alexandre, Gauthier; Alexopoulos, Theodoros; Alhroob, Muhammad; Alimonti, Gianluca; Alio, Lion; Alison, John; Allbrooke, Benedict; Allison, Lee John; Allport, Phillip; Allwood-Spiers, Sarah; Almond, John; Aloisio, Alberto; Alon, Raz; Alonso, Alejandro; Alonso, Francisco; Alpigiani, Cristiano; Altheimer, Andrew David; Alvarez Gonzalez, Barbara; Alviggi, Mariagrazia; Amako, Katsuya; Amaral Coutinho, Yara; Amelung, Christoph; Amidei, Dante; Ammosov, Vladimir; Amor Dos Santos, Susana Patricia; Amorim, Antonio; Amoroso, Simone; Amram, Nir; Amundsen, Glenn; Anastopoulos, Christos; Ancu, Lucian Stefan; Andari, Nansi; Andeen, Timothy; Anders, Christoph Falk; Anders, Gabriel; Anderson, Kelby; Andreazza, Attilio; Andrei, George Victor; Anduaga, Xabier; Angelidakis, Stylianos; Anger, Philipp; Angerami, Aaron; Anghinolfi, Francis; Anisenkov, Alexey; Anjos, Nuno; Annovi, Alberto; Antonaki, Ariadni; Antonelli, Mario; Antonov, Alexey; Antos, Jaroslav; Anulli, Fabio; Aoki, Masato; Aperio Bella, Ludovica; Apolle, Rudi; Arabidze, Giorgi; Aracena, Ignacio; Arai, Yasuo; Araque, Juan Pedro; Arce, Ayana; Arguin, Jean-Francois; Argyropoulos, Spyridon; Arik, Metin; Armbruster, Aaron James; Arnaez, Olivier; Arnal, Vanessa; Arslan, Ozan; Artamonov, Andrei; Artoni, Giacomo; Asai, Shoji; Asbah, Nedaa; Ashkenazi, Adi; Ask, Stefan; Åsman, Barbro; Asquith, Lily; Assamagan, Ketevi; Astalos, Robert; Atkinson, Markus; Atlay, Naim Bora; Auerbach, Benjamin; Auge, Etienne; Augsten, Kamil; Aurousseau, Mathieu; Avolio, Giuseppe; Azuelos, Georges; Azuma, Yuya; Baak, Max; Bacci, Cesare; Bachacou, Henri; Bachas, Konstantinos; Backes, Moritz; Backhaus, Malte; Backus Mayes, John; Badescu, Elisabeta; Bagiacchi, Paolo; Bagnaia, Paolo; Bai, Yu; Bailey, David; Bain, Travis; Baines, John; Baker, Oliver Keith; Baker, Sarah; Balek, Petr; Balli, Fabrice; Banas, Elzbieta; Banerjee, Swagato; Banfi, Danilo; Bangert, Andrea Michelle; Bannoura, Arwa A E; Bansal, Vikas; Bansil, Hardeep Singh; Barak, Liron; Baranov, Sergei; Barber, Tom; Barberio, Elisabetta Luigia; Barberis, Dario; Barbero, Marlon; Barillari, Teresa; Barisonzi, Marcello; Barklow, Timothy; Barlow, Nick; Barnett, Bruce; Barnett, Michael; Barnovska, Zuzana; Baroncelli, Antonio; Barone, Gaetano; Barr, Alan; Barreiro, Fernando; Barreiro Guimarães da Costa, João; Bartoldus, Rainer; Barton, Adam Edward; Bartos, Pavol; Bartsch, Valeria; Bassalat, Ahmed; Basye, Austin; Bates, Richard; Batkova, Lucia; Batley, Richard; Battistin, Michele; Bauer, Florian; Bawa, Harinder Singh; Beau, Tristan; Beauchemin, Pierre-Hugues; Beccherle, Roberto; Bechtle, Philip; Beck, Hans Peter; Becker, Anne Kathrin; Becker, Sebastian; Beckingham, Matthew; Becot, Cyril; Beddall, Andrew; Beddall, Ayda; Bedikian, Sourpouhi; Bednyakov, Vadim; Bee, Christopher; Beemster, Lars; Beermann, Thomas; Begel, Michael; Behr, Katharina; Belanger-Champagne, Camille; Bell, Paul; Bell, William; Bella, Gideon; Bellagamba, Lorenzo; Bellerive, Alain; Bellomo, Massimiliano; Belloni, Alberto; Beloborodova, Olga; Belotskiy, Konstantin; Beltramello, Olga; Benary, Odette; Benchekroun, Driss; Bendtz, Katarina; Benekos, Nektarios; Benhammou, Yan; Benhar Noccioli, Eleonora; Benitez Garcia, Jorge-Armando; Benjamin, Douglas; Bensinger, James; Benslama, Kamal; Bentvelsen, Stan; Berge, David; Bergeaas Kuutmann, Elin; Berger, Nicolas; Berghaus, Frank; Berglund, Elina; Beringer, Jürg; Bernard, Clare; Bernat, Pauline; Bernius, Catrin; Bernlochner, Florian Urs; Berry, Tracey; Berta, Peter; Bertella, Claudia; Bertolucci, Federico; Besana, Maria Ilaria; Besjes, Geert-Jan; Bessidskaia, Olga; Besson, Nathalie; Betancourt, Christopher; Bethke, Siegfried; Bhimji, Wahid; Bianchi, Riccardo-Maria; Bianchini, Louis; Bianco, Michele; Biebel, Otmar; Bieniek, Stephen Paul; Bierwagen, Katharina; Biesiada, Jed; Biglietti, Michela; Bilbao De Mendizabal, Javier; Bilokon, Halina; Bindi, Marcello; Binet, Sebastien; Bingul, Ahmet; Bini, Cesare; Black, Curtis; Black, James; Black, Kevin; Blackburn, Daniel; Blair, Robert; Blanchard, Jean-Baptiste; Blazek, Tomas; Bloch, Ingo; Blocker, Craig; Blum, Walter; Blumenschein, Ulrike; Bobbink, Gerjan; Bobrovnikov, Victor; Bocchetta, Simona Serena; Bocci, Andrea; Boddy, Christopher Richard; Boehler, Michael; Boek, Jennifer; Boek, Thorsten Tobias; Bogaerts, Joannes Andreas; Bogdanchikov, Alexander; Bogouch, Andrei; Bohm, Christian; Bohm, Jan; Boisvert, Veronique; Bold, Tomasz; Boldea, Venera; Boldyrev, Alexey; Bolnet, Nayanka Myriam; Bomben, Marco; Bona, Marcella; Boonekamp, Maarten; Borisov, Anatoly; Borissov, Guennadi; Borri, Marcello; Borroni, Sara; Bortfeldt, Jonathan; Bortolotto, Valerio; Bos, Kors; Boscherini, Davide; Bosman, Martine; Boterenbrood, Hendrik; Boudreau, Joseph; Bouffard, Julian; Bouhova-Thacker, Evelina Vassileva; Boumediene, Djamel Eddine; Bourdarios, Claire; Bousson, Nicolas; Boutouil, Sara; Boveia, Antonio; Boyd, James; Boyko, Igor; Bozovic-Jelisavcic, Ivanka; Bracinik, Juraj; Branchini, Paolo; Brandt, Andrew; Brandt, Gerhard; Brandt, Oleg; Bratzler, Uwe; Brau, Benjamin; Brau, James; Braun, Helmut; Brazzale, Simone Federico; Brelier, Bertrand; Brendlinger, Kurt; Brennan, Amelia Jean; Brenner, Richard; Bressler, Shikma; Bristow, Kieran; Bristow, Timothy Michael; Britton, Dave; Brochu, Frederic; Brock, Ian; Brock, Raymond; Bromberg, Carl; Bronner, Johanna; Brooijmans, Gustaaf; Brooks, Timothy; Brooks, William; Brosamer, Jacquelyn; Brost, Elizabeth; Brown, Gareth; Brown, Jonathan; Bruckman de Renstrom, Pawel; Bruncko, Dusan; Bruneliere, Renaud; Brunet, Sylvie; Bruni, Alessia; Bruni, Graziano; Bruschi, Marco; Bryngemark, Lene; Buanes, Trygve; Buat, Quentin; Bucci, Francesca; Buchholz, Peter; Buckingham, Ryan; Buckley, Andrew; Buda, Stelian Ioan; Budagov, Ioulian; Buehrer, Felix; Bugge, Lars; Bugge, Magnar Kopangen; Bulekov, Oleg; Bundock, Aaron Colin; Burckhart, Helfried; Burdin, Sergey; Burghgrave, Blake; Burke, Stephen; Burmeister, Ingo; Busato, Emmanuel; Büscher, Volker; Bussey, Peter; Buszello, Claus-Peter; Butler, Bart; Butler, John; Butt, Aatif Imtiaz; Buttar, Craig; Butterworth, Jonathan; Butti, Pierfrancesco; Buttinger, William; Buzatu, Adrian; Byszewski, Marcin; Cabrera Urbán, Susana; Caforio, Davide; Cakir, Orhan; Calafiura, Paolo; Calderini, Giovanni; Calfayan, Philippe; Calkins, Robert; Caloba, Luiz; Calvet, David; Calvet, Samuel; Camacho Toro, Reina; Camarda, Stefano; Cameron, David; Caminada, Lea Michaela; Caminal Armadans, Roger; Campana, Simone; Campanelli, Mario; Campoverde, Angel; Canale, Vincenzo; Canepa, Anadi; Cantero, Josu; Cantrill, Robert; Cao, Tingting; Capeans Garrido, Maria Del Mar; Caprini, Irinel; Caprini, Mihai; Capua, Marcella; Caputo, Regina; Cardarelli, Roberto; Carli, Tancredi; Carlino, Gianpaolo; Carminati, Leonardo; Caron, Sascha; Carquin, Edson; Carrillo-Montoya, German D; Carter, Antony; Carter, Janet; Carvalho, João; Casadei, Diego; Casado, Maria Pilar; Castaneda-Miranda, Elizabeth; Castelli, Angelantonio; Castillo Gimenez, Victoria; Castro, Nuno Filipe; Catastini, Pierluigi; Catinaccio, Andrea; Catmore, James; Cattai, Ariella; Cattani, Giordano; Caughron, Seth; Cavaliere, Viviana; Cavalli, Donatella; Cavalli-Sforza, Matteo; Cavasinni, Vincenzo; Ceradini, Filippo; Cerio, Benjamin; Cerny, Karel; Santiago Cerqueira, Augusto; Cerri, Alessandro; Cerrito, Lucio; Cerutti, Fabio; Cerv, Matevz; Cervelli, Alberto; Cetin, Serkant Ali; Chafaq, Aziz; Chakraborty, Dhiman; Chalupkova, Ina; Chan, Kevin; Chang, Philip; Chapleau, Bertrand; Chapman, John Derek; Charfeddine, Driss; Charlton, Dave; Chau, Chav Chhiv; Chavez Barajas, Carlos Alberto; Cheatham, Susan; Chegwidden, Andrew; Chekanov, Sergei; Chekulaev, Sergey; Chelkov, Gueorgui; Chelstowska, Magda Anna; Chen, Chunhui; Chen, Hucheng; Chen, Karen; Chen, Liming; Chen, Shenjian; Chen, Xin; Chen, Yujiao; Cheng, Hok Chuen; Cheng, Yangyang; Cheplakov, Alexander; Cherkaoui El Moursli, Rajaa; Chernyatin, Valeriy; Cheu, Elliott; Chevalier, Laurent; Chiarella, Vitaliano; Chiefari, Giovanni; Childers, John Taylor; Chilingarov, Alexandre; Chiodini, Gabriele; Chisholm, Andrew; Chislett, Rebecca Thalatta; Chitan, Adrian; Chizhov, Mihail; Chouridou, Sofia; Chow, Bonnie Kar Bo; Christidi, Ilektra-Athanasia; Chromek-Burckhart, Doris; Chu, Ming-Lee; Chudoba, Jiri; Chytka, Ladislav; Ciapetti, Guido; Ciftci, Abbas Kenan; Ciftci, Rena; Cinca, Diane; Cindro, Vladimir; Ciocio, Alessandra; Cirkovic, Predrag; Citron, Zvi Hirsh; Citterio, Mauro; Ciubancan, Mihai; Clark, Allan G; Clark, Philip James; Clarke, Robert; Cleland, Bill; Clemens, Jean-Claude; Clement, Benoit; Clement, Christophe; Coadou, Yann; Cobal, Marina; Coccaro, Andrea; Cochran, James H; Coffey, Laurel; Cogan, Joshua Godfrey; Coggeshall, James; Cole, Brian; Cole, Stephen; Colijn, Auke-Pieter; Collins-Tooth, Christopher; Collot, Johann; Colombo, Tommaso; Colon, German; Compostella, Gabriele; Conde Muiño, Patricia; Coniavitis, Elias; Conidi, Maria Chiara; Connell, Simon Henry; Connelly, Ian; Consonni, Sofia Maria; Consorti, Valerio; Constantinescu, Serban; Conta, Claudio; Conti, Geraldine; Conventi, Francesco; Cooke, Mark; Cooper, Ben; Cooper-Sarkar, Amanda; Cooper-Smith, Neil; Copic, Katherine; Cornelissen, Thijs; Corradi, Massimo; Corriveau, Francois; Corso-Radu, Alina; Cortes-Gonzalez, Arely; Cortiana, Giorgio; Costa, Giuseppe; Costa, María José; Costanzo, Davide; Côté, David; Cottin, Giovanna; Cowan, Glen; Cox, Brian; Cranmer, Kyle; Cree, Graham; Crépé-Renaudin, Sabine; Crescioli, Francesco; Crispin Ortuzar, Mireia; Cristinziani, Markus; Crosetti, Giovanni; Cuciuc, Constantin-Mihai; Cuenca Almenar, Cristóbal; Cuhadar Donszelmann, Tulay; Cummings, Jane; Curatolo, Maria; Cuthbert, Cameron; Czirr, Hendrik; Czodrowski, Patrick; Czyczula, Zofia; D'Auria, Saverio; D'Onofrio, Monica; Da Cunha Sargedas De Sousa, Mario Jose; Da Via, Cinzia; Dabrowski, Wladyslaw; Dafinca, Alexandru; Dai, Tiesheng; Dale, Orjan; Dallaire, Frederick; Dallapiccola, Carlo; Dam, Mogens; Daniells, Andrew Christopher; Dano Hoffmann, Maria; Dao, Valerio; Darbo, Giovanni; Darlea, Georgiana Lavinia; Darmora, Smita; Dassoulas, James; Davey, Will; David, Claire; Davidek, Tomas; Davies, Eleanor; Davies, Merlin; Davignon, Olivier; Davison, Adam; Davison, Peter; Davygora, Yuriy; Dawe, Edmund; Dawson, Ian; Daya-Ishmukhametova, Rozmin; De, Kaushik; de Asmundis, Riccardo; De Castro, Stefano; De Cecco, Sandro; de Graat, Julien; De Groot, Nicolo; de Jong, Paul; De La Taille, Christophe; De la Torre, Hector; De Lorenzi, Francesco; De Nooij, Lucie; De Pedis, Daniele; De Salvo, Alessandro; De Sanctis, Umberto; De Santo, Antonella; De Vivie De Regie, Jean-Baptiste; De Zorzi, Guido; Dearnaley, William James; Debbe, Ramiro; Debenedetti, Chiara; Dechenaux, Benjamin; Dedovich, Dmitri; Degenhardt, James; Deigaard, Ingrid; Del Peso, Jose; Del Prete, Tarcisio; Deliot, Frederic; Delitzsch, Chris Malena; Deliyergiyev, Maksym; Dell'Acqua, Andrea; Dell'Asta, Lidia; Dell'Orso, Mauro; Della Pietra, Massimo; della Volpe, Domenico; Delmastro, Marco; Delsart, Pierre-Antoine; Deluca, Carolina; Demers, Sarah; Demichev, Mikhail; Demilly, Aurelien; Denisov, Sergey; Derendarz, Dominik; Derkaoui, Jamal Eddine; Derue, Frederic; Dervan, Paul; Desch, Klaus Kurt; Deterre, Cecile; Deviveiros, Pier-Olivier; Dewhurst, Alastair; Dhaliwal, Saminder; Di Ciaccio, Anna; Di Ciaccio, Lucia; Di Domenico, Antonio; Di Donato, Camilla; Di Girolamo, Alessandro; Di Girolamo, Beniamino; Di Mattia, Alessandro; Di Micco, Biagio; Di Nardo, Roberto; Di Simone, Andrea; Di Sipio, Riccardo; Di Valentino, David; Diaz, Marco Aurelio; Diehl, Edward; Dietrich, Janet; Dietzsch, Thorsten; Diglio, Sara; Dimitrievska, Aleksandra; Dingfelder, Jochen; Dionisi, Carlo; Dita, Petre; Dita, Sanda; Dittus, Fridolin; Djama, Fares; Djobava, Tamar; Barros do Vale, Maria Aline; Do Valle Wemans, André; Doan, Thi Kieu Oanh; Dobos, Daniel; Dobson, Ellie; Doglioni, Caterina; Doherty, Tom; Dohmae, Takeshi; Dolejsi, Jiri; Dolezal, Zdenek; Dolgoshein, Boris; Donadelli, Marisilvia; Donati, Simone; Dondero, Paolo; Donini, Julien; Dopke, Jens; Doria, Alessandra; Dos Anjos, Andre; Dova, Maria-Teresa; Doyle, Tony; Dris, Manolis; Dubbert, Jörg; Dube, Sourabh; Dubreuil, Emmanuelle; Duchovni, Ehud; Duckeck, Guenter; Ducu, Otilia Anamaria; Duda, Dominik; Dudarev, Alexey; Dudziak, Fanny; Duflot, Laurent; Duguid, Liam; Dührssen, Michael; Dunford, Monica; Duran Yildiz, Hatice; Düren, Michael; Durglishvili, Archil; Dwuznik, Michal; Dyndal, Mateusz; Ebke, Johannes; Edson, William; Edwards, Nicholas Charles; Ehrenfeld, Wolfgang; Eifert, Till; Eigen, Gerald; Einsweiler, Kevin; Ekelof, Tord; El Kacimi, Mohamed; Ellert, Mattias; Elles, Sabine; Ellinghaus, Frank; Ellis, Nicolas; Elmsheuser, Johannes; Elsing, Markus; Emeliyanov, Dmitry; Enari, Yuji; Endner, Oliver Chris; Endo, Masaki; Engelmann, Roderich; Erdmann, Johannes; Ereditato, Antonio; Eriksson, Daniel; Ernis, Gunar; Ernst, Jesse; Ernst, Michael; Ernwein, Jean; Errede, Deborah; Errede, Steven; Ertel, Eugen; Escalier, Marc; Esch, Hendrik; Escobar, Carlos; Esposito, Bellisario; Etienvre, Anne-Isabelle; Etzion, Erez; Evans, Hal; Fabbri, Laura; Facini, Gabriel; Fakhrutdinov, Rinat; Falciano, Speranza; Fang, Yaquan; Fanti, Marcello; Farbin, Amir; Farilla, Addolorata; Farooque, Trisha; Farrell, Steven; Farrington, Sinead; Farthouat, Philippe; Fassi, Farida; Fassnacht, Patrick; Fassouliotis, Dimitrios; Favareto, Andrea; Fayard, Louis; Federic, Pavol; Fedin, Oleg; Fedorko, Wojciech; Fehling-Kaschek, Mirjam; Feigl, Simon; Feligioni, Lorenzo; Feng, Cunfeng; Feng, Eric; Feng, Haolu; Fenyuk, Alexander; Fernandez Perez, Sonia; Ferrag, Samir; Ferrando, James; Ferrara, Valentina; Ferrari, Arnaud; Ferrari, Pamela; Ferrari, Roberto; Ferreira de Lima, Danilo Enoque; Ferrer, Antonio; Ferrere, Didier; Ferretti, Claudio; Ferretto Parodi, Andrea; Fiascaris, Maria; Fiedler, Frank; Filipčič, Andrej; Filipuzzi, Marco; Filthaut, Frank; Fincke-Keeler, Margret; Finelli, Kevin Daniel; Fiolhais, Miguel; Fiorini, Luca; Firan, Ana; Fischer, Julia; Fisher, Matthew; Fisher, Wade Cameron; Fitzgerald, Eric Andrew; Flechl, Martin; Fleck, Ivor; Fleischmann, Philipp; Fleischmann, Sebastian; Fletcher, Gareth Thomas; Fletcher, Gregory; Flick, Tobias; Floderus, Anders; Flores Castillo, Luis; Florez Bustos, Andres Carlos; Flowerdew, Michael; Formica, Andrea; Forti, Alessandra; Fortin, Dominique; Fournier, Daniel; Fox, Harald; Fracchia, Silvia; Francavilla, Paolo; Franchini, Matteo; Franchino, Silvia; Francis, David; Franklin, Melissa; Franz, Sebastien; Fraternali, Marco; French, Sky; Friedrich, Conrad; Friedrich, Felix; Froidevaux, Daniel; Frost, James; Fukunaga, Chikara; Fullana Torregrosa, Esteban; Fulsom, Bryan Gregory; Fuster, Juan; Gabaldon, Carolina; Gabizon, Ofir; Gabrielli, Alessandro; Gabrielli, Andrea; Gadatsch, Stefan; Gadomski, Szymon; Gagliardi, Guido; Gagnon, Pauline; Galea, Cristina; Galhardo, Bruno; Gallas, Elizabeth; Gallo, Valentina Santina; Gallop, Bruce; Gallus, Petr; Galster, Gorm Aske Gram Krohn; Gan, KK; Gandrajula, Reddy Pratap; Gao, Jun; Gao, Yongsheng; Garay Walls, Francisca; Garberson, Ford; García, Carmen; García Navarro, José Enrique; Garcia-Sciveres, Maurice; Gardner, Robert; Garelli, Nicoletta; Garonne, Vincent; Gatti, Claudio; Gaudio, Gabriella; Gaur, Bakul; Gauthier, Lea; Gauzzi, Paolo; Gavrilenko, Igor; Gay, Colin; Gaycken, Goetz; Gazis, Evangelos; Ge, Peng; Gecse, Zoltan; Gee, Norman; Geerts, Daniël Alphonsus Adrianus; Geich-Gimbel, Christoph; Gellerstedt, Karl; Gemme, Claudia; Gemmell, Alistair; Genest, Marie-Hélène; Gentile, Simonetta; George, Matthias; George, Simon; Gerbaudo, Davide; Gershon, Avi; Ghazlane, Hamid; Ghodbane, Nabil; Giacobbe, Benedetto; Giagu, Stefano; Giangiobbe, Vincent; Giannetti, Paola; Gianotti, Fabiola; Gibbard, Bruce; Gibson, Stephen; Gilchriese, Murdock; Gillam, Thomas; Gillberg, Dag; Gilles, Geoffrey; Gingrich, Douglas; Giokaris, Nikos; Giordani, MarioPaolo; Giordano, Raffaele; Giorgi, Francesco Michelangelo; Giraud, Pierre-Francois; Giugni, Danilo; Giuliani, Claudia; Giulini, Maddalena; Gjelsten, Børge Kile; Gkialas, Ioannis; Gladilin, Leonid; Glasman, Claudia; Glatzer, Julian; Glaysher, Paul; Glazov, Alexandre; Glonti, George; Goblirsch-Kolb, Maximilian; Goddard, Jack Robert; Godfrey, Jennifer; Godlewski, Jan; Goeringer, Christian; Goldfarb, Steven; Golling, Tobias; Golubkov, Dmitry; Gomes, Agostinho; Gomez Fajardo, Luz Stella; Gonçalo, Ricardo; Goncalves Pinto Firmino Da Costa, Joao; Gonella, Laura; González de la Hoz, Santiago; Gonzalez Parra, Garoe; Gonzalez Silva, Laura; Gonzalez-Sevilla, Sergio; Goossens, Luc; Gorbounov, Petr Andreevich; Gordon, Howard; Gorelov, Igor; Gorfine, Grant; Gorini, Benedetto; Gorini, Edoardo; Gorišek, Andrej; Gornicki, Edward; Goshaw, Alfred; Gössling, Claus; Gostkin, Mikhail Ivanovitch; Gouighri, Mohamed; Goujdami, Driss; Goulette, Marc Phillippe; Goussiou, Anna; Goy, Corinne; Gozpinar, Serdar; Grabas, Herve Marie Xavier; Graber, Lars; Grabowska-Bold, Iwona; Grafström, Per; Grahn, Karl-Johan; Gramling, Johanna; Gramstad, Eirik; Grancagnolo, Francesco; Grancagnolo, Sergio; Grassi, Valerio; Gratchev, Vadim; Gray, Heather; Graziani, Enrico; Grebenyuk, Oleg; Greenwood, Zeno Dixon; Gregersen, Kristian; Gregor, Ingrid-Maria; Grenier, Philippe; Griffiths, Justin; Grigalashvili, Nugzar; Grillo, Alexander; Grimm, Kathryn; Grinstein, Sebastian; Gris, Philippe Luc Yves; Grishkevich, Yaroslav; Grivaz, Jean-Francois; Grohs, Johannes Philipp; Grohsjean, Alexander; Gross, Eilam; Grosse-Knetter, Joern; Grossi, Giulio Cornelio; Groth-Jensen, Jacob; Grout, Zara Jane; Grybel, Kai; Guan, Liang; Guescini, Francesco; Guest, Daniel; Gueta, Orel; Guicheney, Christophe; Guido, Elisa; Guillemin, Thibault; Guindon, Stefan; Gul, Umar; Gumpert, Christian; Gunther, Jaroslav; Guo, Jun; Gupta, Shaun; Gutierrez, Phillip; Gutierrez Ortiz, Nicolas Gilberto; Gutschow, Christian; Guttman, Nir; Guyot, Claude; Gwenlan, Claire; Gwilliam, Carl; Haas, Andy; Haber, Carl; Hadavand, Haleh Khani; Haddad, Nacim; Haefner, Petra; Hageboeck, Stephan; Hajduk, Zbigniew; Hakobyan, Hrachya; Haleem, Mahsana; Hall, David; Halladjian, Garabed; Hamacher, Klaus; Hamal, Petr; Hamano, Kenji; Hamer, Matthias; Hamilton, Andrew; Hamilton, Samuel; Hamnett, Phillip George; Han, Liang; Hanagaki, Kazunori; Hanawa, Keita; Hance, Michael; Hanke, Paul; Hansen, John Renner; Hansen, Jørgen Beck; Hansen, Jorn Dines; Hansen, Peter Henrik; Hara, Kazuhiko; Hard, Andrew; Harenberg, Torsten; Harkusha, Siarhei; Harper, Devin; Harrington, Robert; Harris, Orin; Harrison, Paul Fraser; Hartjes, Fred; Hasegawa, Satoshi; Hasegawa, Yoji; Hasib, A; Hassani, Samira; Haug, Sigve; Hauschild, Michael; Hauser, Reiner; Havranek, Miroslav; Hawkes, Christopher; Hawkings, Richard John; Hawkins, Anthony David; Hayashi, Takayasu; Hayden, Daniel; Hays, Chris; Hayward, Helen; Haywood, Stephen; Head, Simon; Heck, Tobias; Hedberg, Vincent; Heelan, Louise; Heim, Sarah; Heim, Timon; Heinemann, Beate; Heinrich, Lukas; Heisterkamp, Simon; Hejbal, Jiri; Helary, Louis; Heller, Claudio; Heller, Matthieu; Hellman, Sten; Hellmich, Dennis; Helsens, Clement; Henderson, James; Henderson, Robert; Hengler, Christopher; Henrichs, Anna; Henriques Correia, Ana Maria; Henrot-Versille, Sophie; Hensel, Carsten; Herbert, Geoffrey Henry; Hernández Jiménez, Yesenia; Herrberg-Schubert, Ruth; Herten, Gregor; Hertenberger, Ralf; Hervas, Luis; Hesketh, Gavin Grant; Hessey, Nigel; Hickling, Robert; Higón-Rodriguez, Emilio; Hill, John; Hiller, Karl Heinz; Hillert, Sonja; Hillier, Stephen; Hinchliffe, Ian; Hines, Elizabeth; Hirose, Minoru; Hirschbuehl, Dominic; Hobbs, John; Hod, Noam; Hodgkinson, Mark; Hodgson, Paul; Hoecker, Andreas; Hoeferkamp, Martin; Hoffman, Julia; Hoffmann, Dirk; Hofmann, Julia Isabell; Hohlfeld, Marc; Holmes, Tova Ray; Hong, Tae Min; Hooft van Huysduynen, Loek; Hostachy, Jean-Yves; Hou, Suen; Hoummada, Abdeslam; Howard, Jacob; Howarth, James; Hrabovsky, Miroslav; Hristova, Ivana; Hrivnac, Julius; Hryn'ova, Tetiana; Hsu, Pai-hsien Jennifer; Hsu, Shih-Chieh; Hu, Diedi; Hu, Xueye; Huang, Yanping; Hubacek, Zdenek; Hubaut, Fabrice; Huegging, Fabian; Huffman, Todd Brian; Hughes, Emlyn; Hughes, Gareth; Huhtinen, Mika; Hülsing, Tobias Alexander; Hurwitz, Martina; Huseynov, Nazim; Huston, Joey; Huth, John; Iacobucci, Giuseppe; Iakovidis, Georgios; Ibragimov, Iskander; Iconomidou-Fayard, Lydia; Idarraga, John; Ideal, Emma; Iengo, Paolo; Igonkina, Olga; Iizawa, Tomoya; Ikegami, Yoichi; Ikematsu, Katsumasa; Ikeno, Masahiro; Iliadis, Dimitrios; Ilic, Nikolina; Inamaru, Yuki; Ince, Tayfun; Ioannou, Pavlos; Iodice, Mauro; Iordanidou, Kalliopi; Ippolito, Valerio; Irles Quiles, Adrian; Isaksson, Charlie; Ishino, Masaya; Ishitsuka, Masaki; Ishmukhametov, Renat; Issever, Cigdem; Istin, Serhat; Iturbe Ponce, Julia Mariana; Ivashin, Anton; Iwanski, Wieslaw; Iwasaki, Hiroyuki; Izen, Joseph; Izzo, Vincenzo; Jackson, Brett; Jackson, John; Jackson, Matthew; Jackson, Paul; Jaekel, Martin; Jain, Vivek; Jakobs, Karl; Jakobsen, Sune; Jakoubek, Tomas; Jakubek, Jan; Jamin, David Olivier; Jana, Dilip; Jansen, Eric; Jansen, Hendrik; Janssen, Jens; Janus, Michel; Jarlskog, Göran; Javůrek, Tomáš; Jeanty, Laura; Jeng, Geng-yuan; Jennens, David; Jenni, Peter; Jentzsch, Jennifer; Jeske, Carl; Jézéquel, Stéphane; Ji, Haoshuang; Ji, Weina; Jia, Jiangyong; Jiang, Yi; Jimenez Belenguer, Marcos; Jin, Shan; Jinaru, Adam; Jinnouchi, Osamu; Joergensen, Morten Dam; Johansson, Erik; Johansson, Per; Johns, Kenneth; Jon-And, Kerstin; Jones, Graham; Jones, Roger; Jones, Tim; Jongmanns, Jan; Jorge, Pedro; Joshi, Kiran Daniel; Jovicevic, Jelena; Ju, Xiangyang; Jung, Christian; Jungst, Ralph Markus; Jussel, Patrick; Juste Rozas, Aurelio; Kaci, Mohammed; Kaczmarska, Anna; Kado, Marumi; Kagan, Harris; Kagan, Michael; Kajomovitz, Enrique; Kama, Sami; Kanaya, Naoko; Kaneda, Michiru; Kaneti, Steven; Kanno, Takayuki; Kantserov, Vadim; Kanzaki, Junichi; Kaplan, Benjamin; Kapliy, Anton; Kar, Deepak; Karakostas, Konstantinos; Karastathis, Nikolaos; Karnevskiy, Mikhail; Karpov, Sergey; Karthik, Krishnaiyengar; Kartvelishvili, Vakhtang; Karyukhin, Andrey; Kashif, Lashkar; Kasieczka, Gregor; Kass, Richard; Kastanas, Alex; Kataoka, Yousuke; Katre, Akshay; Katzy, Judith; Kaushik, Venkatesh; Kawagoe, Kiyotomo; Kawamoto, Tatsuo; Kawamura, Gen; Kazama, Shingo; Kazanin, Vassili; Kazarinov, Makhail; Keeler, Richard; Keener, Paul; Kehoe, Robert; Keil, Markus; Keller, John; Keoshkerian, Houry; Kepka, Oldrich; Kerševan, Borut Paul; Kersten, Susanne; Kessoku, Kohei; Keung, Justin; Khalil-zada, Farkhad; Khandanyan, Hovhannes; Khanov, Alexander; Khodinov, Alexander; Khomich, Andrei; Khoo, Teng Jian; Khoriauli, Gia; Khoroshilov, Andrey; Khovanskiy, Valery; Khramov, Evgeniy; Khubua, Jemal; Kim, Hee Yeun; Kim, Hyeon Jin; Kim, Shinhong; Kimura, Naoki; Kind, Oliver; King, Barry; King, Matthew; King, Robert Steven Beaufoy; King, Samuel Burton; Kirk, Julie; Kiryunin, Andrey; Kishimoto, Tomoe; Kisielewska, Danuta; Kiss, Florian; Kitamura, Takumi; Kittelmann, Thomas; Kiuchi, Kenji; Kladiva, Eduard; Klein, Max; Klein, Uta; Kleinknecht, Konrad; Klimek, Pawel; Klimentov, Alexei; Klingenberg, Reiner; Klinger, Joel Alexander; Klinkby, Esben; Klioutchnikova, Tatiana; Klok, Peter; Kluge, Eike-Erik; Kluit, Peter; Kluth, Stefan; Kneringer, Emmerich; Knoops, Edith; Knue, Andrea; Kobayashi, Tomio; Kobel, Michael; Kocian, Martin; Kodys, Peter; Koevesarki, Peter; Koffas, Thomas; Koffeman, Els; Kogan, Lucy Anne; Kohlmann, Simon; Kohout, Zdenek; Kohriki, Takashi; Koi, Tatsumi; Kolanoski, Hermann; Koletsou, Iro; Koll, James; Komar, Aston; Komori, Yuto; Kondo, Takahiko; Kondrashova, Nataliia; Köneke, Karsten; König, Adriaan; König, Sebastian; Kono, Takanori; Konoplich, Rostislav; Konstantinidis, Nikolaos; Kopeliansky, Revital; Koperny, Stefan; Köpke, Lutz; Kopp, Anna Katharina; Korcyl, Krzysztof; Kordas, Kostantinos; Korn, Andreas; Korol, Aleksandr; Korolkov, Ilya; Korolkova, Elena; Korotkov, Vladislav; Kortner, Oliver; Kortner, Sandra; Kostyukhin, Vadim; Kotov, Sergey; Kotov, Vladislav; Kotwal, Ashutosh; Kourkoumelis, Christine; Kouskoura, Vasiliki; Koutsman, Alex; Kowalewski, Robert Victor; Kowalski, Tadeusz; Kozanecki, Witold; Kozhin, Anatoly; Kral, Vlastimil; Kramarenko, Viktor; Kramberger, Gregor; Krasnopevtsev, Dimitriy; Krasny, Mieczyslaw Witold; Krasznahorkay, Attila; Kraus, Jana; Kravchenko, Anton; Kreiss, Sven; Kretz, Moritz; Kretzschmar, Jan; Kreutzfeldt, Kristof; Krieger, Peter; Kroeninger, Kevin; Kroha, Hubert; Kroll, Joe; Kroseberg, Juergen; Krstic, Jelena; Kruchonak, Uladzimir; Krüger, Hans; Kruker, Tobias; Krumnack, Nils; Krumshteyn, Zinovii; Kruse, Amanda; Kruse, Mark; Kruskal, Michael; Kubota, Takashi; Kuday, Sinan; Kuehn, Susanne; Kugel, Andreas; Kuhl, Andrew; Kuhl, Thorsten; Kukhtin, Victor; Kulchitsky, Yuri; Kuleshov, Sergey; Kuna, Marine; Kunkle, Joshua; Kupco, Alexander; Kurashige, Hisaya; Kurochkin, Yurii; Kurumida, Rie; Kus, Vlastimil; Kuwertz, Emma Sian; Kuze, Masahiro; Kvita, Jiri; La Rosa, Alessandro; La Rotonda, Laura; Labarga, Luis; Lacasta, Carlos; Lacava, Francesco; Lacey, James; Lacker, Heiko; Lacour, Didier; Lacuesta, Vicente Ramón; Ladygin, Evgueni; Lafaye, Remi; Laforge, Bertrand; Lagouri, Theodota; Lai, Stanley; Laier, Heiko; Lambourne, Luke; Lammers, Sabine; Lampen, Caleb; Lampl, Walter; Lançon, Eric; Landgraf, Ulrich; Landon, Murrough; Lang, Valerie Susanne; Lange, Clemens; Lankford, Andrew; Lanni, Francesco; Lantzsch, Kerstin; Lanza, Agostino; Laplace, Sandrine; Lapoire, Cecile; Laporte, Jean-Francois; Lari, Tommaso; Lassnig, Mario; Laurelli, Paolo; Lavorini, Vincenzo; Lavrijsen, Wim; Law, Alexander; Laycock, Paul; Le, Bao Tran; Le Dortz, Olivier; Le Guirriec, Emmanuel; Le Menedeu, Eve; LeCompte, Thomas; Ledroit-Guillon, Fabienne Agnes Marie; Lee, Claire Alexandra; Lee, Hurng-Chun; Lee, Jason; Lee, Shih-Chang; Lee, Lawrence; Lefebvre, Guillaume; Lefebvre, Michel; Legger, Federica; Leggett, Charles; Lehan, Allan; Lehmacher, Marc; Lehmann Miotto, Giovanna; Lei, Xiaowen; Leister, Andrew Gerard; Leite, Marco Aurelio Lisboa; Leitner, Rupert; Lellouch, Daniel; Lemmer, Boris; Leney, Katharine; Lenz, Tatjana; Lenzen, Georg; Lenzi, Bruno; Leone, Robert; Leonhardt, Kathrin; Leontsinis, Stefanos; Leroy, Claude; Lester, Christopher; Lester, Christopher Michael; Levêque, Jessica; Levin, Daniel; Levinson, Lorne; Levy, Mark; Lewis, Adrian; Lewis, George; Leyko, Agnieszka; Leyton, Michael; Li, Bing; Li, Bo; Li, Haifeng; Li, Ho Ling; Li, Shu; Li, Xuefei; Li, Yichen; Liang, Zhijun; Liao, Hongbo; Liberti, Barbara; Lichard, Peter; Lie, Ki; Liebal, Jessica; Liebig, Wolfgang; Limbach, Christian; Limosani, Antonio; Limper, Maaike; Lin, Simon; Linde, Frank; Lindquist, Brian Edward; Linnemann, James; Lipeles, Elliot; Lipniacka, Anna; Lisovyi, Mykhailo; Liss, Tony; Lissauer, David; Lister, Alison; Litke, Alan; Liu, Bo; Liu, Dong; Liu, Jianbei; Liu, Kun; Liu, Lulu; Liu, Miaoyuan; Liu, Minghui; Liu, Yanwen; Livan, Michele; Livermore, Sarah; Lleres, Annick; Llorente Merino, Javier; Lloyd, Stephen; Lo Sterzo, Francesco; Lobodzinska, Ewelina; Loch, Peter; Lockman, William; Loddenkoetter, Thomas; Loebinger, Fred; Loevschall-Jensen, Ask Emil; Loginov, Andrey; Loh, Chang Wei; Lohse, Thomas; Lohwasser, Kristin; Lokajicek, Milos; Lombardo, Vincenzo Paolo; Long, Jonathan; Long, Robin Eamonn; Lopes, Lourenco; Lopez Mateos, David; Lopez Paredes, Brais; Lorenz, Jeanette; Lorenzo Martinez, Narei; Losada, Marta; Loscutoff, Peter; Lou, XinChou; Lounis, Abdenour; Love, Jeremy; Love, Peter; Lowe, Andrew; Lu, Feng; Lubatti, Henry; Luci, Claudio; Lucotte, Arnaud; Luehring, Frederick; Lukas, Wolfgang; Luminari, Lamberto; Lundberg, Olof; Lund-Jensen, Bengt; Lungwitz, Matthias; Lynn, David; Lysak, Roman; Lytken, Else; Ma, Hong; Ma, Lian Liang; Maccarrone, Giovanni; Macchiolo, Anna; Maček, Boštjan; Machado Miguens, Joana; Macina, Daniela; Madaffari, Daniele; Madar, Romain; Maddocks, Harvey Jonathan; Mader, Wolfgang; Madsen, Alexander; Maeno, Mayuko; Maeno, Tadashi; Magradze, Erekle; Mahboubi, Kambiz; Mahlstedt, Joern; Mahmoud, Sara; Maiani, Camilla; Maidantchik, Carmen; Maio, Amélia; Majewski, Stephanie; Makida, Yasuhiro; Makovec, Nikola; Mal, Prolay; Malaescu, Bogdan; Malecki, Pawel; Maleev, Victor; Malek, Fairouz; Mallik, Usha; Malon, David; Malone, Caitlin; Maltezos, Stavros; Malyshev, Vladimir; Malyukov, Sergei; Mamuzic, Judita; Mandelli, Beatrice; Mandelli, Luciano; Mandić, Igor; Mandrysch, Rocco; Maneira, José; Manfredini, Alessandro; Manhaes de Andrade Filho, Luciano; Manjarres Ramos, Joany Andreina; Mann, Alexander; Manning, Peter; Manousakis-Katsikakis, Arkadios; Mansoulie, Bruno; Mantifel, Rodger; Mapelli, Livio; March, Luis; Marchand, Jean-Francois; Marchiori, Giovanni; Marcisovsky, Michal; Marino, Christopher; Marques, Carlos; Marroquim, Fernando; Marsden, Stephen Philip; Marshall, Zach; Marti, Lukas Fritz; Marti-Garcia, Salvador; Martin, Brian; Martin, Brian Thomas; Martin, Jean-Pierre; Martin, Tim; Martin, Victoria Jane; Martin dit Latour, Bertrand; Martinez, Homero; Martinez, Mario; Martin-Haugh, Stewart; Martyniuk, Alex; Marx, Marilyn; Marzano, Francesco; Marzin, Antoine; Masetti, Lucia; Mashimo, Tetsuro; Mashinistov, Ruslan; Masik, Jiri; Maslennikov, Alexey; Massa, Ignazio; Massol, Nicolas; Mastrandrea, Paolo; Mastroberardino, Anna; Masubuchi, Tatsuya; Matricon, Pierre; Matsunaga, Hiroyuki; Matsushita, Takashi; Mättig, Peter; Mättig, Stefan; Mattmann, Johannes; Maurer, Julien; Maxfield, Stephen; Maximov, Dmitriy; Mazini, Rachid; Mazzaferro, Luca; Mc Goldrick, Garrin; Mc Kee, Shawn Patrick; McCarn, Allison; McCarthy, Robert; McCarthy, Tom; McCubbin, Norman; McFarlane, Kenneth; Mcfayden, Josh; Mchedlidze, Gvantsa; Mclaughlan, Tom; McMahon, Steve; McPherson, Robert; Meade, Andrew; Mechnich, Joerg; Medinnis, Michael; Meehan, Samuel; Meera-Lebbai, Razzak; Mehlhase, Sascha; Mehta, Andrew; Meier, Karlheinz; Meineck, Christian; Meirose, Bernhard; Melachrinos, Constantinos; Mellado Garcia, Bruce Rafael; Meloni, Federico; Mengarelli, Alberto; Menke, Sven; Meoni, Evelin; Mercurio, Kevin Michael; Mergelmeyer, Sebastian; Meric, Nicolas; Mermod, Philippe; Merola, Leonardo; Meroni, Chiara; Merritt, Frank; Merritt, Hayes; Messina, Andrea; Metcalfe, Jessica; Mete, Alaettin Serhan; Meyer, Carsten; Meyer, Christopher; Meyer, Jean-Pierre; Meyer, Jochen; Middleton, Robin; Migas, Sylwia; Mijović, Liza; Mikenberg, Giora; Mikestikova, Marcela; Mikuž, Marko; Miller, David; Mills, Corrinne; Milov, Alexander; Milstead, David; Milstein, Dmitry; Minaenko, Andrey; Miñano Moya, Mercedes; Minashvili, Irakli; Mincer, Allen; Mindur, Bartosz; Mineev, Mikhail; Ming, Yao; Mir, Lluisa-Maria; Mirabelli, Giovanni; Mitani, Takashi; Mitrevski, Jovan; Mitsou, Vasiliki A; Mitsui, Shingo; Miucci, Antonio; Miyagawa, Paul; Mjörnmark, Jan-Ulf; Moa, Torbjoern; Mochizuki, Kazuya; Moeller, Victoria; Mohapatra, Soumya; Mohr, Wolfgang; Molander, Simon; Moles-Valls, Regina; Mönig, Klaus; Monini, Caterina; Monk, James; Monnier, Emmanuel; Montejo Berlingen, Javier; Monticelli, Fernando; Monzani, Simone; Moore, Roger; Mora Herrera, Clemencia; Moraes, Arthur; Morange, Nicolas; Morel, Julien; Moreno, Deywis; Moreno Llácer, María; Morettini, Paolo; Morgenstern, Marcus; Morii, Masahiro; Moritz, Sebastian; Morley, Anthony Keith; Mornacchi, Giuseppe; Morris, John; Morvaj, Ljiljana; Moser, Hans-Guenther; Mosidze, Maia; Moss, Josh; Mount, Richard; Mountricha, Eleni; Mouraviev, Sergei; Moyse, Edward; Muanza, Steve; Mudd, Richard; Mueller, Felix; Mueller, James; Mueller, Klemens; Mueller, Thibaut; Mueller, Timo; Muenstermann, Daniel; Munwes, Yonathan; Murillo Quijada, Javier Alberto; Murray, Bill; Musheghyan, Haykuhi; Musto, Elisa; Myagkov, Alexey; Myska, Miroslav; Nackenhorst, Olaf; Nadal, Jordi; Nagai, Koichi; Nagai, Ryo; Nagai, Yoshikazu; Nagano, Kunihiro; Nagarkar, Advait; Nagasaka, Yasushi; Nagel, Martin; Nairz, Armin Michael; Nakahama, Yu; Nakamura, Koji; Nakamura, Tomoaki; Nakano, Itsuo; Namasivayam, Harisankar; Nanava, Gizo; Narayan, Rohin; Nattermann, Till; Naumann, Thomas; Navarro, Gabriela; Nayyar, Ruchika; Neal, Homer; Nechaeva, Polina; Neep, Thomas James; Negri, Andrea; Negri, Guido; Negrini, Matteo; Nektarijevic, Snezana; Nelson, Andrew; Nelson, Timothy Knight; Nemecek, Stanislav; Nemethy, Peter; Nepomuceno, Andre Asevedo; Nessi, Marzio; Neubauer, Mark; Neumann, Manuel; Neves, Ricardo; Nevski, Pavel; Newcomer, Mitchel; Newman, Paul; Nguyen, Duong Hai; Nickerson, Richard; Nicolaidou, Rosy; Nicquevert, Bertrand; Nielsen, Jason; Nikiforou, Nikiforos; Nikiforov, Andriy; Nikolaenko, Vladimir; Nikolic-Audit, Irena; Nikolics, Katalin; Nikolopoulos, Konstantinos; Nilsson, Paul; Ninomiya, Yoichi; Nisati, Aleandro; Nisius, Richard; Nobe, Takuya; Nodulman, Lawrence; Nomachi, Masaharu; Nomidis, Ioannis; Norberg, Scarlet; Nordberg, Markus; Novakova, Jana; Nowak, Sebastian; Nozaki, Mitsuaki; Nozka, Libor; Ntekas, Konstantinos; Nunes Hanninger, Guilherme; Nunnemann, Thomas; Nurse, Emily; Nuti, Francesco; O'Brien, Brendan Joseph; O'grady, Fionnbarr; O'Neil, Dugan; O'Shea, Val; Oakham, Gerald; Oberlack, Horst; Obermann, Theresa; Ocariz, Jose; Ochi, Atsuhiko; Ochoa, Ines; Oda, Susumu; Odaka, Shigeru; Ogren, Harold; Oh, Alexander; Oh, Seog; Ohm, Christian; Ohman, Henrik; Ohshima, Takayoshi; Okamura, Wataru; Okawa, Hideki; Okumura, Yasuyuki; Okuyama, Toyonobu; Olariu, Albert; Olchevski, Alexander; Olivares Pino, Sebastian Andres; Oliveira Damazio, Denis; Oliver Garcia, Elena; Olivito, Dominick; Olszewski, Andrzej; Olszowska, Jolanta; Onofre, António; Onyisi, Peter; Oram, Christopher; Oreglia, Mark; Oren, Yona; Orestano, Domizia; Orlando, Nicola; Oropeza Barrera, Cristina; Orr, Robert; Osculati, Bianca; Ospanov, Rustem; Otero y Garzon, Gustavo; Otono, Hidetoshi; Ouchrif, Mohamed; Ouellette, Eric; Ould-Saada, Farid; Ouraou, Ahmimed; Oussoren, Koen Pieter; Ouyang, Qun; Ovcharova, Ana; Owen, Mark; Ozcan, Veysi Erkcan; Ozturk, Nurcan; Pachal, Katherine; Pacheco Pages, Andres; Padilla Aranda, Cristobal; Pagáčová, Martina; Pagan Griso, Simone; Paganis, Efstathios; Pahl, Christoph; Paige, Frank; Pais, Preema; Pajchel, Katarina; Palacino, Gabriel; Palestini, Sandro; Pallin, Dominique; Palma, Alberto; Palmer, Jody; Pan, Yibin; Panagiotopoulou, Evgenia; Panduro Vazquez, William; Pani, Priscilla; Panikashvili, Natalia; Panitkin, Sergey; Pantea, Dan; Paolozzi, Lorenzo; Papadopoulou, Theodora; Papageorgiou, Konstantinos; Paramonov, Alexander; Paredes Hernandez, Daniela; Parker, Michael Andrew; Parodi, Fabrizio; Parsons, John; Parzefall, Ulrich; Pasqualucci, Enrico; Passaggio, Stefano; Passeri, Antonio; Pastore, Fernanda; Pastore, Francesca; Pásztor, Gabriella; Pataraia, Sophio; Patel, Nikhul; Pater, Joleen; Patricelli, Sergio; Pauly, Thilo; Pearce, James; Pedersen, Maiken; Pedraza Lopez, Sebastian; Pedro, Rute; Peleganchuk, Sergey; Pelikan, Daniel; Peng, Haiping; Penning, Bjoern; Penwell, John; Perepelitsa, Dennis; Perez Codina, Estel; Pérez García-Estañ, María Teresa; Perez Reale, Valeria; Perini, Laura; Pernegger, Heinz; Perrino, Roberto; Peschke, Richard; Peshekhonov, Vladimir; Peters, Krisztian; Peters, Yvonne; Petersen, Brian; Petersen, Jorgen; Petersen, Troels; Petit, Elisabeth; Petridis, Andreas; Petridou, Chariclia; Petrolo, Emilio; Petrucci, Fabrizio; Petteni, Michele; Pettersson, Nora Emilia; Pezoa, Raquel; Phillips, Peter William; Piacquadio, Giacinto; Pianori, Elisabetta; Picazio, Attilio; Piccaro, Elisa; Piccinini, Maurizio; Piec, Sebastian Marcin; Piegaia, Ricardo; Pignotti, David; Pilcher, James; Pilkington, Andrew; Pina, João Antonio; Pinamonti, Michele; Pinder, Alex; Pinfold, James; Pingel, Almut; Pinto, Belmiro; Pires, Sylvestre; Pizio, Caterina; Pleier, Marc-Andre; Pleskot, Vojtech; Plotnikova, Elena; Plucinski, Pawel; Poddar, Sahill; Podlyski, Fabrice; Poettgen, Ruth; Poggioli, Luc; Pohl, David-leon; Pohl, Martin; Polesello, Giacomo; Policicchio, Antonio; Polifka, Richard; Polini, Alessandro; Pollard, Christopher Samuel; Polychronakos, Venetios; Pommès, Kathy; Pontecorvo, Ludovico; Pope, Bernard; Popeneciu, Gabriel Alexandru; Popovic, Dragan; Poppleton, Alan; Portell Bueso, Xavier; Pospelov, Guennady; Pospisil, Stanislav; Potamianos, Karolos; Potrap, Igor; Potter, Christina; Potter, Christopher; Poulard, Gilbert; Poveda, Joaquin; Pozdnyakov, Valery; Prabhu, Robindra; Pralavorio, Pascal; Pranko, Aliaksandr; Prasad, Srivas; Pravahan, Rishiraj; Prell, Soeren; Price, Darren; Price, Joe; Price, Lawrence; Prieur, Damien; Primavera, Margherita; Proissl, Manuel; Prokofiev, Kirill; Prokoshin, Fedor; Protopapadaki, Eftychia-sofia; Protopopescu, Serban; Proudfoot, James; Przybycien, Mariusz; Przysiezniak, Helenka; Ptacek, Elizabeth; Pueschel, Elisa; Puldon, David; Purohit, Milind; Puzo, Patrick; Pylypchenko, Yuriy; Qian, Jianming; Qin, Gang; Quadt, Arnulf; Quarrie, David; Quayle, William; Quilty, Donnchadha; Qureshi, Anum; Radeka, Veljko; Radescu, Voica; Radhakrishnan, Sooraj Krishnan; Radloff, Peter; Rados, Pere; Ragusa, Francesco; Rahal, Ghita; Rajagopalan, Srinivasan; Rammensee, Michael; Rammes, Marcus; Randle-Conde, Aidan Sean; Rangel-Smith, Camila; Rao, Kanury; Rauscher, Felix; Rave, Tobias Christian; Ravenscroft, Thomas; Raymond, Michel; Read, Alexander Lincoln; Rebuzzi, Daniela; Redelbach, Andreas; Redlinger, George; Reece, Ryan; Reeves, Kendall; Rehnisch, Laura; Reinsch, Andreas; Reisin, Hernan; Relich, Matthew; Rembser, Christoph; Ren, Zhongliang; Renaud, Adrien; Rescigno, Marco; Resconi, Silvia; Resende, Bernardo; Reznicek, Pavel; Rezvani, Reyhaneh; Richter, Robert; Ridel, Melissa; Rieck, Patrick; Rijssenbeek, Michael; Rimoldi, Adele; Rinaldi, Lorenzo; Ritsch, Elmar; Riu, Imma; Rizatdinova, Flera; Rizvi, Eram; Robertson, Steven; Robichaud-Veronneau, Andree; Robinson, Dave; Robinson, James; Robson, Aidan; Roda, Chiara; Rodrigues, Luis; Roe, Shaun; Røhne, Ole; Rolli, Simona; Romaniouk, Anatoli; Romano, Marino; Romeo, Gaston; Romero Adam, Elena; Rompotis, Nikolaos; Roos, Lydia; Ros, Eduardo; Rosati, Stefano; Rosbach, Kilian; Rose, Matthew; Rosendahl, Peter Lundgaard; Rosenthal, Oliver; Rossetti, Valerio; Rossi, Elvira; Rossi, Leonardo Paolo; Rosten, Rachel; Rotaru, Marina; Roth, Itamar; Rothberg, Joseph; Rousseau, David; Royon, Christophe; Rozanov, Alexandre; Rozen, Yoram; Ruan, Xifeng; Rubbo, Francesco; Rubinskiy, Igor; Rud, Viacheslav; Rudolph, Christian; Rudolph, Matthew Scott; Rühr, Frederik; Ruiz-Martinez, Aranzazu; Rurikova, Zuzana; Rusakovich, Nikolai; Ruschke, Alexander; Rutherfoord, John; Ruthmann, Nils; Ryabov, Yury; Rybar, Martin; Rybkin, Grigori; Ryder, Nick; Saavedra, Aldo; Sacerdoti, Sabrina; Saddique, Asif; Sadeh, Iftach; Sadrozinski, Hartmut; Sadykov, Renat; Safai Tehrani, Francesco; Sakamoto, Hiroshi; Sakurai, Yuki; Salamanna, Giuseppe; Salamon, Andrea; Saleem, Muhammad; Salek, David; Sales De Bruin, Pedro Henrique; Salihagic, Denis; Salnikov, Andrei; Salt, José; Salvachua Ferrando, Belén; Salvatore, Daniela; Salvatore, Pasquale Fabrizio; Salvucci, Antonio; Salzburger, Andreas; Sampsonidis, Dimitrios; Sanchez, Arturo; Sánchez, Javier; Sanchez Martinez, Victoria; Sandaker, Heidi; Sander, Heinz Georg; Sanders, Michiel; Sandhoff, Marisa; Sandoval, Tanya; Sandoval, Carlos; Sandstroem, Rikard; Sankey, Dave; Sansoni, Andrea; Santoni, Claudio; Santonico, Rinaldo; Santos, Helena; Santoyo Castillo, Itzebelt; Sapp, Kevin; Sapronov, Andrey; Saraiva, João; Sarrazin, Bjorn; Sartisohn, Georg; Sasaki, Osamu; Sasaki, Yuichi; Satsounkevitch, Igor; Sauvage, Gilles; Sauvan, Emmanuel; Savard, Pierre; Savu, Dan Octavian; Sawyer, Craig; Sawyer, Lee; Saxon, David; Saxon, James; Sbarra, Carla; Sbrizzi, Antonio; Scanlon, Tim; Scannicchio, Diana; Scarcella, Mark; Schaarschmidt, Jana; Schacht, Peter; Schaefer, Douglas; Schaefer, Ralph; Schaelicke, Andreas; Schaepe, Steffen; Schaetzel, Sebastian; Schäfer, Uli; Schaffer, Arthur; Schaile, Dorothee; Schamberger, R. Dean; Scharf, Veit; Schegelsky, Valery; Scheirich, Daniel; Schernau, Michael; Scherzer, Max; Schiavi, Carlo; Schieck, Jochen; Schillo, Christian; Schioppa, Marco; Schlenker, Stefan; Schmidt, Evelyn; Schmieden, Kristof; Schmitt, Christian; Schmitt, Christopher; Schmitt, Sebastian; Schneider, Basil; Schnellbach, Yan Jie; Schnoor, Ulrike; Schoeffel, Laurent; Schoening, Andre; Schoenrock, Bradley Daniel; Schorlemmer, Andre Lukas; Schott, Matthias; Schouten, Doug; Schovancova, Jaroslava; Schram, Malachi; Schramm, Steven; Schreyer, Manuel; Schroeder, Christian; Schuh, Natascha; Schultens, Martin Johannes; Schultz-Coulon, Hans-Christian; Schulz, Holger; Schumacher, Markus; Schumm, Bruce; Schune, Philippe; Schwartzman, Ariel; Schwegler, Philipp; Schwemling, Philippe; Schwienhorst, Reinhard; Schwindling, Jerome; Schwindt, Thomas; Schwoerer, Maud; Sciacca, Gianfranco; Scifo, Estelle; Sciolla, Gabriella; Scott, Bill; Scuri, Fabrizio; Scutti, Federico; Searcy, Jacob; Sedov, George; Sedykh, Evgeny; Seidel, Sally; Seiden, Abraham; Seifert, Frank; Seixas, José; Sekhniaidze, Givi; Sekula, Stephen; Selbach, Karoline Elfriede; Seliverstov, Dmitry; Sellers, Graham; Semprini-Cesari, Nicola; Serfon, Cedric; Serin, Laurent; Serkin, Leonid; Serre, Thomas; Seuster, Rolf; Severini, Horst; Sforza, Federico; Sfyrla, Anna; Shabalina, Elizaveta; Shamim, Mansoora; Shan, Lianyou; Shank, James; Shao, Qi Tao; Shapiro, Marjorie; Shatalov, Pavel; Shaw, Kate; Sherwood, Peter; Shimizu, Shima; Shimmin, Chase Owen; Shimojima, Makoto; Shin, Taeksu; Shiyakova, Mariya; Shmeleva, Alevtina; Shochet, Mel; Short, Daniel; Shrestha, Suyog; Shulga, Evgeny; Shupe, Michael; Shushkevich, Stanislav; Sicho, Petr; Sidorov, Dmitri; Sidoti, Antonio; Siegert, Frank; Sijacki, Djordje; Silbert, Ohad; Silva, José; Silver, Yiftah; Silverstein, Daniel; Silverstein, Samuel; Simak, Vladislav; Simard, Olivier; Simic, Ljiljana; Simion, Stefan; Simioni, Eduard; Simmons, Brinick; Simoniello, Rosa; Simonyan, Margar; Sinervo, Pekka; Sinev, Nikolai; Sipica, Valentin; Siragusa, Giovanni; Sircar, Anirvan; Sisakyan, Alexei; Sivoklokov, Serguei; Sjölin, Jörgen; Sjursen, Therese; Skinnari, Louise Anastasia; Skottowe, Hugh Philip; Skovpen, Kirill; Skubic, Patrick; Slater, Mark; Slavicek, Tomas; Sliwa, Krzysztof; Smakhtin, Vladimir; Smart, Ben; Smestad, Lillian; Smirnov, Sergei; Smirnov, Yury; Smirnova, Lidia; Smirnova, Oxana; Smith, Kenway; Smizanska, Maria; Smolek, Karel; Snesarev, Andrei; Snidero, Giacomo; Snow, Joel; Snyder, Scott; Sobie, Randall; Socher, Felix; Sodomka, Jaromir; Soffer, Abner; Soh, Dart-yin; Solans, Carlos; Solar, Michael; Solc, Jaroslav; Soldatov, Evgeny; Soldevila, Urmila; Solfaroli Camillocci, Elena; Solodkov, Alexander; Solovyanov, Oleg; Solovyev, Victor; Sommer, Philip; Song, Hong Ye; Soni, Nitesh; Sood, Alexander; Sopko, Vit; Sopko, Bruno; Sorin, Veronica; Sosebee, Mark; Soualah, Rachik; Soueid, Paul; Soukharev, Andrey; South, David; Spagnolo, Stefania; Spanò, Francesco; Spearman, William Robert; Spighi, Roberto; Spigo, Giancarlo; Spousta, Martin; Spreitzer, Teresa; Spurlock, Barry; St Denis, Richard Dante; Staerz, Steffen; Stahlman, Jonathan; Stamen, Rainer; Stanecka, Ewa; Stanek, Robert; Stanescu, Cristian; Stanescu-Bellu, Madalina; Stanitzki, Marcel Michael; Stapnes, Steinar; Starchenko, Evgeny; Stark, Jan; Staroba, Pavel; Starovoitov, Pavel; Staszewski, Rafal; Stavina, Pavel; Steele, Genevieve; Steinberg, Peter; Stekl, Ivan; Stelzer, Bernd; Stelzer, Harald Joerg; Stelzer-Chilton, Oliver; Stenzel, Hasko; Stern, Sebastian; Stewart, Graeme; Stillings, Jan Andre; Stockton, Mark; Stoebe, Michael; Stoerig, Kathrin; Stoicea, Gabriel; Stolte, Philipp; Stonjek, Stefan; Stradling, Alden; Straessner, Arno; Strandberg, Jonas; Strandberg, Sara; Strandlie, Are; Strauss, Emanuel; Strauss, Michael; Strizenec, Pavol; Ströhmer, Raimund; Strom, David; Stroynowski, Ryszard; Stucci, Stefania Antonia; Stugu, Bjarne; Styles, Nicholas Adam; Su, Dong; Su, Jun; Subramania, Halasya Siva; Subramaniam, Rajivalochan; Succurro, Antonella; Sugaya, Yorihito; Suhr, Chad; Suk, Michal; Sulin, Vladimir; Sultansoy, Saleh; Sumida, Toshi; Sun, Xiaohu; Sundermann, Jan Erik; Suruliz, Kerim; Susinno, Giancarlo; Sutton, Mark; Suzuki, Yu; Svatos, Michal; Swedish, Stephen; Swiatlowski, Maximilian; Sykora, Ivan; Sykora, Tomas; Ta, Duc; Tackmann, Kerstin; Taenzer, Joe; Taffard, Anyes; Tafirout, Reda; Taiblum, Nimrod; Takahashi, Yuta; Takai, Helio; Takashima, Ryuichi; Takeda, Hiroshi; Takeshita, Tohru; Takubo, Yosuke; Talby, Mossadek; Talyshev, Alexey; Tam, Jason; Tamsett, Matthew; Tan, Kong Guan; Tanaka, Junichi; Tanaka, Reisaburo; Tanaka, Satoshi; Tanaka, Shuji; Tanasijczuk, Andres Jorge; Tani, Kazutoshi; Tannoury, Nancy; Tapprogge, Stefan; Tarem, Shlomit; Tarrade, Fabien; Tartarelli, Giuseppe Francesco; Tas, Petr; Tasevsky, Marek; Tashiro, Takuya; Tassi, Enrico; Tavares Delgado, Ademar; Tayalati, Yahya; Taylor, Christopher; Taylor, Frank; Taylor, Geoffrey; Taylor, Wendy; Teischinger, Florian Alfred; Teixeira Dias Castanheira, Matilde; Teixeira-Dias, Pedro; Temming, Kim Katrin; Ten Kate, Herman; Teng, Ping-Kun; Terada, Susumu; Terashi, Koji; Terron, Juan; Terzo, Stefano; Testa, Marianna; Teuscher, Richard; Therhaag, Jan; Theveneaux-Pelzer, Timothée; Thoma, Sascha; Thomas, Juergen; Thomas-Wilsker, Joshuha; Thompson, Emily; Thompson, Paul; Thompson, Peter; Thompson, Stan; Thomsen, Lotte Ansgaard; Thomson, Evelyn; Thomson, Mark; Thong, Wai Meng; Thun, Rudolf; Tian, Feng; Tibbetts, Mark James; Tikhomirov, Vladimir; Tikhonov, Yury; Timoshenko, Sergey; Tiouchichine, Elodie; Tipton, Paul; Tisserant, Sylvain; Todorov, Theodore; Todorova-Nova, Sharka; Toggerson, Brokk; Tojo, Junji; Tokár, Stanislav; Tokushuku, Katsuo; Tollefson, Kirsten; Tomlinson, Lee; Tomoto, Makoto; Tompkins, Lauren; Toms, Konstantin; Topilin, Nikolai; Torrence, Eric; Torres, Heberth; Torró Pastor, Emma; Toth, Jozsef; Touchard, Francois; Tovey, Daniel; Tran, Huong Lan; Trefzger, Thomas; Tremblet, Louis; Tricoli, Alessandro; Trigger, Isabel Marian; Trincaz-Duvoid, Sophie; Tripiana, Martin; Triplett, Nathan; Trischuk, William; Trocmé, Benjamin; Troncon, Clara; Trottier-McDonald, Michel; Trovatelli, Monica; True, Patrick; Trzebinski, Maciej; Trzupek, Adam; Tsarouchas, Charilaos; Tseng, Jeffrey; Tsiareshka, Pavel; Tsionou, Dimitra; Tsipolitis, Georgios; Tsirintanis, Nikolaos; Tsiskaridze, Shota; Tsiskaridze, Vakhtang; Tskhadadze, Edisher; Tsukerman, Ilya; Tsulaia, Vakhtang; Tsuno, Soshi; Tsybychev, Dmitri; Tua, Alan; Tudorache, Alexandra; Tudorache, Valentina; Tuna, Alexander Naip; Tupputi, Salvatore; Turchikhin, Semen; Turecek, Daniel; Turk Cakir, Ilkay; Turra, Ruggero; Tuts, Michael; Tykhonov, Andrii; Tylmad, Maja; Tyndel, Mike; Uchida, Kirika; Ueda, Ikuo; Ueno, Ryuichi; Ughetto, Michael; Ugland, Maren; Uhlenbrock, Mathias; Ukegawa, Fumihiko; Unal, Guillaume; Undrus, Alexander; Unel, Gokhan; Ungaro, Francesca; Unno, Yoshinobu; Urbaniec, Dustin; Urquijo, Phillip; Usai, Giulio; Usanova, Anna; Vacavant, Laurent; Vacek, Vaclav; Vachon, Brigitte; Valencic, Nika; Valentinetti, Sara; Valero, Alberto; Valery, Loic; Valkar, Stefan; Valladolid Gallego, Eva; Vallecorsa, Sofia; Valls Ferrer, Juan Antonio; Van Berg, Richard; Van Der Deijl, Pieter; van der Geer, Rogier; van der Graaf, Harry; Van Der Leeuw, Robin; van der Ster, Daniel; van Eldik, Niels; van Gemmeren, Peter; Van Nieuwkoop, Jacobus; van Vulpen, Ivo; van Woerden, Marius Cornelis; Vanadia, Marco; Vandelli, Wainer; Vanguri, Rami; Vaniachine, Alexandre; Vankov, Peter; Vannucci, Francois; Vardanyan, Gagik; Vari, Riccardo; Varnes, Erich; Varol, Tulin; Varouchas, Dimitris; Vartapetian, Armen; Varvell, Kevin; Vassilakopoulos, Vassilios; Vazeille, Francois; Vazquez Schroeder, Tamara; Veatch, Jason; Veloso, Filipe; Veneziano, Stefano; Ventura, Andrea; Ventura, Daniel; Venturi, Manuela; Venturi, Nicola; Venturini, Alessio; Vercesi, Valerio; Verducci, Monica; Verkerke, Wouter; Vermeulen, Jos; Vest, Anja; Vetterli, Michel; Viazlo, Oleksandr; Vichou, Irene; Vickey, Trevor; Vickey Boeriu, Oana Elena; Viehhauser, Georg; Viel, Simon; Vigne, Ralph; Villa, Mauro; Villaplana Perez, Miguel; Vilucchi, Elisabetta; Vincter, Manuella; Vinogradov, Vladimir; Virzi, Joseph; Vitells, Ofer; Vivarelli, Iacopo; Vives Vaque, Francesc; Vlachos, Sotirios; Vladoiu, Dan; Vlasak, Michal; Vogel, Adrian; Vokac, Petr; Volpi, Guido; Volpi, Matteo; von der Schmitt, Hans; von Radziewski, Holger; von Toerne, Eckhard; Vorobel, Vit; Vorobev, Konstantin; Vos, Marcel; Voss, Rudiger; Vossebeld, Joost; Vranjes, Nenad; Vranjes Milosavljevic, Marija; Vrba, Vaclav; Vreeswijk, Marcel; Vu Anh, Tuan; Vuillermet, Raphael; Vukotic, Ilija; Vykydal, Zdenek; Wagner, Wolfgang; Wagner, Peter; Wahrmund, Sebastian; Wakabayashi, Jun; Walder, James; Walker, Rodney; Walkowiak, Wolfgang; Wall, Richard; Waller, Peter; Walsh, Brian; Wang, Chao; Wang, Chiho; Wang, Fuquan; Wang, Haichen; Wang, Hulin; Wang, Jike; Wang, Jin; Wang, Kuhan; Wang, Rui; Wang, Song-Ming; Wang, Tan; Wang, Xiaoxiao; Warburton, Andreas; Ward, Patricia; Wardrope, David Robert; Warsinsky, Markus; Washbrook, Andrew; Wasicki, Christoph; Watanabe, Ippei; Watkins, Peter; Watson, Alan; Watson, Ian; Watson, Miriam; Watts, Gordon; Watts, Stephen; Waugh, Ben; Webb, Samuel; Weber, Michele; Weber, Stefan Wolf; Webster, Jordan S; Weidberg, Anthony; Weigell, Philipp; Weinert, Benjamin; Weingarten, Jens; Weiser, Christian; Weits, Hartger; Wells, Phillippa; Wenaus, Torre; Wendland, Dennis; Weng, Zhili; Wengler, Thorsten; Wenig, Siegfried; Wermes, Norbert; Werner, Matthias; Werner, Per; Wessels, Martin; Wetter, Jeffrey; Whalen, Kathleen; White, Andrew; White, Martin; White, Ryan; White, Sebastian; Whiteson, Daniel; Wicke, Daniel; Wickens, Fred; Wiedenmann, Werner; Wielers, Monika; Wienemann, Peter; Wiglesworth, Craig; Wiik-Fuchs, Liv Antje Mari; Wijeratne, Peter Alexander; Wildauer, Andreas; Wildt, Martin Andre; Wilkens, Henric George; Will, Jonas Zacharias; Williams, Hugh; Williams, Sarah; Willis, Christopher; Willocq, Stephane; Wilson, John; Wilson, Alan; Wingerter-Seez, Isabelle; Winkelmann, Stefan; Winklmeier, Frank; Wittgen, Matthias; Wittig, Tobias; Wittkowski, Josephine; Wollstadt, Simon Jakob; Wolter, Marcin Wladyslaw; Wolters, Helmut; Wosiek, Barbara; Wotschack, Jorg; Woudstra, Martin; Wozniak, Krzysztof; Wright, Michael; Wu, Mengqing; Wu, Sau Lan; Wu, Xin; Wu, Yusheng; Wulf, Evan; Wyatt, Terry Richard; Wynne, Benjamin; Xella, Stefania; Xiao, Meng; Xu, Da; Xu, Lailin; Yabsley, Bruce; Yacoob, Sahal; Yamada, Miho; Yamaguchi, Hiroshi; Yamaguchi, Yohei; Yamamoto, Akira; Yamamoto, Kyoko; Yamamoto, Shimpei; Yamamura, Taiki; Yamanaka, Takashi; Yamauchi, Katsuya; Yamazaki, Yuji; Yan, Zhen; Yang, Haijun; Yang, Hongtao; Yang, Un-Ki; Yang, Yi; Yanush, Serguei; Yao, Liwen; Yao, Weiming; Yasu, Yoshiji; Yatsenko, Elena; Yau Wong, Kaven Henry; Ye, Jingbo; Ye, Shuwei; Yen, Andy L; Yildirim, Eda; Yilmaz, Metin; Yoosoofmiya, Reza; Yorita, Kohei; Yoshida, Rikutaro; Yoshihara, Keisuke; Young, Charles; Young, Christopher John; Youssef, Saul; Yu, David Ren-Hwa; Yu, Jaehoon; Yu, Jiaming; Yu, Jie; Yuan, Li; Yurkewicz, Adam; Zabinski, Bartlomiej; Zaidan, Remi; Zaitsev, Alexander; Zaman, Aungshuman; Zambito, Stefano; Zanello, Lucia; Zanzi, Daniele; Zaytsev, Alexander; Zeitnitz, Christian; Zeman, Martin; Zemla, Andrzej; Zengel, Keith; Zenin, Oleg; Ženiš, Tibor; Zerwas, Dirk; Zevi della Porta, Giovanni; Zhang, Dongliang; Zhang, Fangzhou; Zhang, Huaqiao; Zhang, Jinlong; Zhang, Lei; Zhang, Xueyao; Zhang, Zhiqing; Zhao, Zhengguo; Zhemchugov, Alexey; Zhong, Jiahang; Zhou, Bing; Zhou, Lei; Zhou, Ning; Zhu, Cheng Guang; Zhu, Hongbo; Zhu, Junjie; Zhu, Yingchun; Zhuang, Xuai; Zibell, Andre; Zieminska, Daria; Zimine, Nikolai; Zimmermann, Christoph; Zimmermann, Robert; Zimmermann, Simone; Zimmermann, Stephanie; Zinonos, Zinonas; Ziolkowski, Michael; Zitoun, Robert; Zobernig, Georg; Zoccoli, Antonio; zur Nedden, Martin; Zurzolo, Giovanni; Zutshi, Vishnu; Zwalinski, Lukasz

    2014-05-27

    A measurement of the parity-violating decay asymmetry parameter, $\\alpha_b$, and the helicity amplitudes for the decay $\\Lambda_b^0\\to J/\\psi(\\mu^+\\mu^-) \\Lambda^0 (p\\pi^-)$ is reported. The analysis is based on 1400 $\\Lambda_b^0$ and $\\bar{\\Lambda}_b^0$ baryons selected in $4.6~\\rm{fb}^{-1}$ of proton--proton collision data with a center-of-mass energy of 7 TeV recorded by the ATLAS experiment at the LHC. By combining the $\\Lambda_b^0$ and $\\bar{\\Lambda}_b^0$ samples under the assumption of $CP$ conservation, the value of $\\alpha_b$ is measured to be $0.30\\pm0.16 ({\\rm stat})\\pm 0.06 ({\\rm syst})$. This measurement provides a test of theoretical models based on perturbative QCD or heavy-quark effective theory.

  13. Decay properties of 68,69,70Mn: Probing collectivity up to N=44 in Fe isotopic chain

    Directory of Open Access Journals (Sweden)

    G. Benzoni

    2015-12-01

    Full Text Available The β decays Mn68→Fe68, Mn69→Fe69 and Mn70→Fe70 have been measured at the RIBF facility at RIKEN using the EURICA γ spectrometer combined with an active stopper consisting of a stack of Si detectors. The nuclei were produced as fission fragments from a beam of 238U at a bombarding energy of 345 MeV/nucleon impinging on a Be target and selected using the BigRIPS separator. Half-lives and β-delayed neutron emission probabilities have been extracted for these decays, together with first experimental information on excited states populated in 69,70Fe. The data indicate a continuously increasing deformation for Fe isotopes up to A=70. This is interpreted, as for Cr isotopes, in terms of the interplay between the quadrupole correlations of the ν1d5/2 and ν0g9/2 orbitals and the monopole component of the π0f7/2–ν0f5/2 interaction.

  14. The esg locus of Myxococcus xanthus encodes the E1 alpha and E1 beta subunits of a branched-chain keto acid dehydrogenase.

    Science.gov (United States)

    Toal, D R; Clifton, S W; Roe, B A; Downard, J

    1995-04-01

    The esg locus of Myxococcus xanthus appears to control the production of a signal that must be transmitted between cells for the completion of multicellular development. DNA sequence analysis suggested that the esg locus encodes the E1 decarboxylase (composed of E1 alpha and E1 beta subunits) of a branched-chain keto acid dehydrogenase (BCKAD) that is involved in branched-chain amino acid (BCAA) metabolism. The properties of an esg::Tn5 insertion mutant supported this conclusion. These properties include: (i) the growth yield of the mutant was reduced with increasing concentrations of the BCAAs in the medium while the growth yield of wild-type cells increased, (ii) mutant extracts were deficient in BCKAD activity, and (iii) growth of the mutant in media with short branched-chain fatty acids related to the expected products of the BCKAD helped to correct the mutant defects in growth, pigmentation and development. The esg BCKAD appears to be involved in the synthesis of long branched-chain fatty acids since the mutant contained reduced levels of this class of compounds. Our results are consistent with a model in which the esg-encoded enzyme is involved in the synthesis of branched-chain fatty acids during vegetative growth, and these compounds are used later in cell-cell signalling during development.

  15. Internal doses of French adult population linked to the intake of radionuclides from the decay-chains of uranium and thorium by foodstuffs ingestion

    International Nuclear Information System (INIS)

    Renaud, Ph.; Parache, V.; Roussel-Debet, S.

    2015-01-01

    This study provides the first dose assessment to the French adult population due to the intake of radionuclides from the decay chains of uranium and thorium by foodstuff ingestion (water consumption excepted). This dose varies widely with the consumption of seafood, from less than 200 μSv.y -1 for people who do not consume shellfish or crustaceans at all, to more than 2,000 μSv.y -1 for the biggest consumers (about 150 kg.y -1 according to specific dietary surveys carried out along the French seaside). For moderate consumers of seafood (around 4.6 kg.y -1 ), who probably represent a major part of the population, this internal dose would be around 330 μSv.y -1 . This variable consumption of seafood overshadows all the other causes of variability of these internal dose estimates. (authors)

  16. Recognition of decay accelerating factor and alpha(v)beta(3) by inactivated hantaviruses: Toward the development of high-throughput screening flow cytometry assays.

    Science.gov (United States)

    Buranda, Tione; Wu, Yang; Perez, Dominique; Jett, Stephen D; BonduHawkins, Virginie; Ye, Chunyan; Edwards, Bruce; Hall, Pamela; Larson, Richard S; Lopez, Gabriel P; Sklar, Larry A; Hjelle, Brian

    2010-07-15

    Hantaviruses cause two severe diseases in humans: hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). The lack of vaccines or specific drugs to prevent or treat HFRS and HCPS and the requirement for conducting experiments in a biosafety level 3 laboratory (BSL-3) limit the ability to probe the mechanism of infection and disease pathogenesis. In this study, we developed a generalizable spectroscopic assay to quantify saturable fluorophore sites solubilized in envelope membranes of Sin Nombre virus (SNV) particles. We then used flow cytometry and live cell confocal fluorescence microscopy imaging to show that ultraviolet (UV)-killed SNV particles bind to the cognate receptors of live virions, namely, decay accelerating factor (DAF/CD55) expressed on Tanoue B cells and alpha(v)beta(3) integrins expressed on Vero E6 cells. SNV binding to DAF is multivalent and of high affinity (K(d) approximately 26pM). Self-exchange competition binding assays between fluorescently labeled SNV and unlabeled SNV are used to evaluate an infectious unit-to-particle ratio of approximately 1:14,000. We configured the assay for measuring the binding of fluorescently labeled SNV to Tanoue B suspension cells using a high-throughput flow cytometer. In this way, we established a proof-of-principle high-throughput screening (HTS) assay for binding inhibition. This is a first step toward developing HTS format assays for small molecule inhibitors of viral-cell interactions as well as dissecting the mechanism of infection in a BSL-2 environment. 2010 Elsevier Inc. All rights reserved.

  17. IL-4 function can be transferred to the IL-2 receptor by tyrosine containing sequences found in the IL-4 receptor alpha chain.

    Science.gov (United States)

    Wang, H Y; Paul, W E; Keegan, A D

    1996-02-01

    IL-4 binds to a cell surface receptor complex that consists of the IL-4 binding protein (IL-4R alpha) and the gamma chain of the IL-2 receptor complex (gamma c). The receptors for IL-4 and IL-2 have several features in common; both use the gamma c as a receptor component, and both activate the Janus kinases JAK-1 and JAK-3. In spite of these similarities, IL-4 evokes specific responses, including the tyrosine phosphorylation of 4PS/IRS-2 and the induction of CD23. To determine whether sequences within the cytoplasmic domain of the IL-4R alpha specify these IL-4-specific responses, we transplanted the insulin IL-4 receptor motif (I4R motif) of the huIL-4R alpha to the cytoplasmic domain of a truncated IL-2R beta. In addition, we transplanted a region that contains peptide sequences shown to block Stat6 binding to DNA. We analyzed the ability of cells expressing these IL-2R-IL-4R chimeric constructs to respond to IL-2. We found that IL-4 function could be transplanted to the IL-2 receptor by these regions and that proliferative and differentiative functions can be induced by different receptor sequences.

  18. The properties of the single chicken MHC classical class II alpha chain (B-LA) gene indicate an ancient origin for the DR/E-like isotype of class II molecules

    DEFF Research Database (Denmark)

    Salomonsen, Jan; Marston, Denise; Avila, David

    2003-01-01

    In mammals, there are MHC class II molecules with distinctive sequence features, such as the classical isotypes DR, DQ and DP. These particular isotypes have not been reported in non-mammalian vertebrates. We have isolated the class II (B-L) alpha chain from outbred chickens as the basis...... DNA, suggesting considerable diversity around the gene. Analysis of a large back-cross family indicates that the class II alpha chain locus ( B-LA) is located roughly 5.6 cM from the MHC locus, which encodes the classical class II beta chains. Thus the chicken class II alpha chain gene is like...... for the cloning and sequencing of the cDNA. We found only one class II alpha chain transcript, which bears the major features of a classical class II alpha sequence, including the critical peptide-binding residues. The chicken sequence is more similar to human DR than to the DQ, DP, DO or DM isotypes, most...

  19. Fcγ receptor I alpha chain (CD64 expression in macrophages is critical for the onset of meningitis by Escherichia coli K1.

    Directory of Open Access Journals (Sweden)

    Rahul Mittal

    2010-11-01

    Full Text Available Neonatal meningitis due to Escherichia coli K1 is a serious illness with unchanged morbidity and mortality rates for the last few decades. The lack of a comprehensive understanding of the mechanisms involved in the development of meningitis contributes to this poor outcome. Here, we demonstrate that depletion of macrophages in newborn mice renders the animals resistant to E. coli K1 induced meningitis. The entry of E. coli K1 into macrophages requires the interaction of outer membrane protein A (OmpA of E. coli K1 with the alpha chain of Fcγ receptor I (FcγRIa, CD64 for which IgG opsonization is not necessary. Overexpression of full-length but not C-terminal truncated FcγRIa in COS-1 cells permits E. coli K1 to enter the cells. Moreover, OmpA binding to FcγRIa prevents the recruitment of the γ-chain and induces a different pattern of tyrosine phosphorylation of macrophage proteins compared to IgG2a induced phosphorylation. Of note, FcγRIa(-/- mice are resistant to E. coli infection due to accelerated clearance of bacteria from circulation, which in turn was the result of increased expression of CR3 on macrophages. Reintroduction of human FcγRIa in mouse FcγRIa(-/- macrophages in vitro increased bacterial survival by suppressing the expression of CR3. Adoptive transfer of wild type macrophages into FcγRIa(-/- mice restored susceptibility to E. coli infection. Together, these results show that the interaction of FcγRI alpha chain with OmpA plays a key role in the development of neonatal meningitis by E. coli K1.

  20. A 19-kDa C-terminal tryptic fragment of the. alpha. chain of Na/K-ATPase is essential for occlusion and transport of cations

    Energy Technology Data Exchange (ETDEWEB)

    Karlish, S.J.D.; Goldshleger, R. (Weizmann Institute of Science, Rehovot (Israel)); Stein, W.D. (Hebrew Univ. Jerusalem (Israel))

    1990-06-01

    Tryptic digestion of pig renal Na/K-ATPase in the presence of Rb and absence of Ca ions removes about half of the protein but leaves a stable 19-kDa membrane-embedded fragment derived from the {alpha} chain, a largely intact {beta} chain, and essentially normal Rb- and Na-occlusion capacity. Subsequent digestion with trypsin in the presence of Ca or absence of Rb ions leads to rapid loss of the 19-kDa fragment and a parallel loss of Rb occlusion, demonstrating that the fragment is essential for occlusion. The N-terminal sequence of the 19-kDa fragment is Asn-Pro-Lys-Thr-Asp-Lys-Leu-Val-Asn-Glu-Arg-Leu-Ile-Ser-Met-Ala, beginning at residue 830 and extending toward the C terminus. Membranes containing the 19-kDa fragment have the following functional properties. (i) ATP-dependent functions are absent. (ii) The apparent affinity for occluding Rb is unchanged, the affinity for Na is lower than in the control enzyme, and activation is now strongly sigmoidal rather than hyperbolic. (iii) Membranes containing the 19-kDa fragment can be reconstituted into phospholipid vesicles and sustain slow Rb-Rb exchange. Thus the transport pathway is retained. The authors conclude that cation occlusion sites and the transport pathway within transmembrane segments are quite separate from the ATP binding sites, located on the cytoplasmic domain of the {alpha} chain. Interactions between cation and ATP sites, the heart of active transport, must be indirect - mediated, presumably, by conformational changes of the protein.

  1. Short-chain consensus alpha-neurotoxin: a synthetic 60-mer peptide with generic traits and enhanced immunogenic properties.

    Science.gov (United States)

    de la Rosa, Guillermo; Corrales-García, Ligia L; Rodriguez-Ruiz, Ximena; López-Vera, Estuardo; Corzo, Gerardo

    2018-04-06

    The three-fingered toxin family and more precisely short-chain α-neurotoxins (also known as Type I α-neurotoxins) are crucial in defining the elapid envenomation process, but paradoxically, they are barely neutralized by current elapid snake antivenoms. This work has been focused on the primary structural identity among Type I neurotoxins in order to create a consensus short-chain α-neurotoxin with conserved characteristics. A multiple sequence alignment considering the twelve most toxic short-chain α-neurotoxins reported from the venoms of the elapid genera Acanthophis, Oxyuranus, Walterinnesia, Naja, Dendroaspis and Micrurus led us to propose a short-chain consensus α-neurotoxin, here named ScNtx. The synthetic ScNtx gene was de novo constructed and cloned into the expression vector pQE30 containing a 6His-Tag and an FXa proteolytic cleavage region. Escherichia coli Origami cells transfected with the pQE30/ScNtx vector expressed the recombinant consensus neurotoxin in a soluble form with a yield of 1.5 mg/L of culture medium. The 60-amino acid residue ScNtx contains canonical structural motifs similar to α-neurotoxins from African elapids and its LD 50 of 3.8 µg/mice is similar to the most toxic short-chain α-neurotoxins reported from elapid venoms. Furthermore, ScNtx was also able to antagonize muscular, but not neuronal, nicotinic acetylcholine receptors (nAChR). Rabbits immunized with ScNtx were able to immune-recognize short-chain α-neurotoxins within whole elapid venoms. Type I neurotoxins are difficult to isolate and purify from natural sources; therefore, the heterologous expression of molecules such ScNtx, bearing crucial motifs and key amino acids, is a step forward to create common immunogens for developing cost-effective antivenoms with a wider spectrum of efficacy, quality and strong therapeutic value.

  2. Alkylation of amide linkages and cleavage of the C chain in the enzyme-activated-substrate inhibition of alpha-chymotrypsin with N-nitrosamides

    International Nuclear Information System (INIS)

    Donadio, S.; Perks, H.M.; Tsuchiya, K.; White, E.H.

    1985-01-01

    Active-site-directed N-nitrosamides inhibit alpha-chymotrypsin through an enzyme-activated-substrate mechanism. In this work, the activation results in the release--in the active site--of benzyl carbonium ions, which alkylate and inhibit the enzyme. The final ratio of benzyl groups to enzyme molecules is 1.0, but the alkyl groups are scattered over a number of sites. Reduction and alkylation of the inhibited enzyme generate peptides insoluble in most media. Guanidine hydrochloride at 6 M proved a good solvent, and its use as an eluant on G-75 Sephadex permitted separation of the peptides. In the case of 14 C-labeled enzyme, such an approach has shown that all of the alkylation occurs on the C chain of the enzyme, the chain of which the active site is constructed. Chemical modification of the peptides with ethylenediamine and N-[3-(dimethylamino)propyl]-N'-ethylcarbodiimide rendered them soluble in dilute acid, permitting high-performance liquid chromatographic separation. Model studies have shown that the benzyl carbonium ions are highly reactive, alkylating amide linkages at both oxygen and nitrogen. Chromatography of this mixture and also 13 C NMR spectroscopy of the intact inhibited enzyme have shown that three major N-alkylations have occurred. Tryptic digestion of the C chain of chymotrypsin, which contains all of the alkylation sites, provides evidence that the stable N sites are principally located between residue 216 and residue 230

  3. Determination of rate constants and branching ratios for TCE degradation by zero-valent iron using a chain decay multispecies model.

    Science.gov (United States)

    Hwang, Hyoun-Tae; Jeen, Sung-Wook; Sudicky, Edward A; Illman, Walter A

    2015-01-01

    The applicability of a newly-developed chain-decay multispecies model (CMM) was validated by obtaining kinetic rate constants and branching ratios along the reaction pathways of trichloroethene (TCE) reduction by zero-valent iron (ZVI) from column experiments. Changes in rate constants and branching ratios for individual reactions for degradation products over time for two columns under different geochemical conditions were examined to provide ranges of those parameters expected over the long-term. As compared to the column receiving deionized water, the column receiving dissolved CaCO3 showed higher mean degradation rates for TCE and all of its degradation products. However, the column experienced faster reactivity loss toward TCE degradation due to precipitation of secondary carbonate minerals, as indicated by a higher value for the ratio of maximum to minimum TCE degradation rate observed over time. From the calculated branching ratios, it was found that TCE and cis-dichloroethene (cis-DCE) were dominantly dechlorinated to chloroacetylene and acetylene, respectively, through reductive elimination for both columns. The CMM model, validated by the column test data in this study, provides a convenient tool to determine simultaneously the critical design parameters for permeable reactive barriers and natural attenuation such as rate constants and branching ratios. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. ITIH4 (inter-alpha-trypsin inhibitor heavy chain 4) is a new acute-phase protein isolated from cattle during experimental infection

    DEFF Research Database (Denmark)

    Pineiro, M.; Andres, M.; Iturralde, M.

    2004-01-01

    , the heavy chain 4 of the inter-alpha-trypsin inhibitor family. The response of this protein in the sera was determined for animals during experimental bacterial and viral infections. In the bacterial model, animals were inoculated with a mixture of Actinomyces pyogenes, Fusobacterium necrophorum......, and Peptostreptococcus indolicus to induce an acute-phase reaction. All animals developed moderate to severe clinical mastitis and exhibited remarkable increases in ITIH4 concentration in serum (from 3 to 12 times the initial values, peaking at 48 to 72 h after infection) that correlated with the severity of the disease....... Because of the significant induction of the protein in the animals in the mastitis and BRSV infection models, we can conclude that ITIH4 is a new positive acute-phase protein in cattle....

  5. Complementary DNA sequences encoding the multimammate rat MHC class II DQ alpha and beta chains and cross-species sequence comparison in rodents.

    Science.gov (United States)

    de Bellocq, J Goüy; Leirs, H

    2009-09-01

    Sequences of the complete open reading frame (ORF) for rodents major histocompatibility complex (MHC) class II genes are rare. Multimammate rat (Mastomys natalensis) complementary DNA (cDNA) encoding the alpha and beta chains of MHC class II DQ gene was cloned from a rapid amplifications of cDNA Emds (RACE) cDNA library. The ORFs consist of 801 and 771 bp encoding 266 and 256 amino acid residues for DQB and DQA, respectively. The genomic structure of Mana-DQ genes is globally analogous to that described for other rodents except for the insertion of a serine residue in the signal peptide of Mana-DQB, which is unique among known rodents.

  6. Substitution of arginine for glycine at position 154 of the {alpha}1 chain of type I collagen in a variant of osteogenesis imperfecta: Comparison to previous cases with the same mutation

    Energy Technology Data Exchange (ETDEWEB)

    Zhuang, J.; Tromp, G.; Kuivaniemi, H.; Prockop, D.J. [Thomas Jefferson Univ., Philadelphia, PA (United States); Castells, S. [Univ. Hospital of Brooklyn, NY (United States)

    1996-01-11

    A substitution of arginine for glycine at amino acid position 154 of the {alpha}1(I) collagen chain was found in a father and his three children. The phenotype of the patients includes manifestations of types I and III/IV osteogenesis imperfecta, but appears to be milder than that of the previously described two unrelated patients that had the identical mutation in the {alpha}1(I) collagen chain. The variability in the phenotype raises the possibility of epistatic loci or environmental effects on expression of the disorder. 35 refs., 3 figs., 2 tabs.

  7. Measurement of the parity-violating asymmetry parameter alpha_b and the helicity amplitudes for the decay Lambda_b->J/psi+Lambda with the ATLAS detector

    Czech Academy of Sciences Publication Activity Database

    Aad, G.; Abajyan, T.; Abbott, B.; Böhm, Jan; Chudoba, Jiří; Havránek, Miroslav; Hejbal, Jiří; Jakoubek, Tomáš; Kepka, Oldřich; Kupčo, Alexander; Kůs, Vlastimil; Lokajíček, Miloš; Lysák, Roman; Marčišovský, Michal; Mikeštíková, Marcela; Myška, Miroslav; Němeček, Stanislav; Šícho, Petr; Staroba, Pavel; Svatoš, Michal; Taševský, Marek; Vrba, Václav

    2014-01-01

    Roč. 89, č. 9 (2014), "092009-1"-"092009-12" ISSN 1550-7998 R&D Projects: GA MŠk(CZ) LG13009 Institutional support: RVO:68378271 Keywords : J/psi(3100) * leptonic decay * ATLAS * CERN LHC Coll * Heavy Quark Effective Theory * Lambda/b0 * hadronic decay Subject RIV: BF - Elementary Particles and High Energy Physics Impact factor: 4.643, year: 2014

  8. miR-451 deficiency is associated with altered endometrial fibrinogen alpha chain expression and reduced endometriotic implant establishment in an experimental mouse model.

    Directory of Open Access Journals (Sweden)

    Warren B Nothnick

    Full Text Available Endometriosis is defined as the growth of endometrial glandular and stromal components in ectopic locations and affects as many as 10% of all women of reproductive age. Despite its high prevalence, the pathogenesis of endometriosis remains poorly understood. MicroRNAs, small non-coding RNAs that post-transcriptionally regulate gene expression, are mis-expressed in endometriosis but a functional role in the disease pathogenesis remains uncertain. To examine the role of microRNA-451 (miR-451 in the initial development of endometriosis, we utilized a novel mouse model in which eutopic endometrial fragments used to induce endometriosis were deficient for miR-451. After induction of the disease, we evaluated the impact of this deficiency on implant development and survival. Loss of miR-451 expression resulted in a lower number of ectopic lesions established in vivo. Analysis of differential protein profiles between miR-451 deficient and wild-type endometrial fragments revealed that fibrinogen alpha polypeptide isoform 2 precursor was approximately 2-fold higher in the miR-451 null donor endometrial tissue and this elevated expression of the protein was associated with altered expression of the parent fibrinogen alpha chain mRNA and protein. As this polypeptide contains RGD amino acid "cell adhesion" motifs which could impact early establishment of lesion development, we examined and confirmed using a cyclic RGD peptide antagonist, that endometrial cell adhesion and endometriosis establishment could be respectively inhibited both in vitro and in vivo. Collectively, these results suggest that the reduced miR-451 eutopic endometrial expression does not enhance initial establishment of these fragments when displaced into the peritoneal cavity, that loss of eutopic endometrial miR-451 expression is associated with altered expression of fibrinogen alpha chain mRNA and protein, and that RGD cyclic peptide antagonists inhibit establishment of endometriosis

  9. Structural and Thermodynamic Basis for Weak Interactions between Dihydrolipoamide Dehydrogenase and Subunit-binding Domain of the Branched-chain [alpha]-Ketoacid Dehydrogenase Complex

    Energy Technology Data Exchange (ETDEWEB)

    Brautigam, Chad A.; Wynn, R. Max; Chuang, Jacinta L.; Naik, Mandar T.; Young, Brittany B.; Huang, Tai-huang; Chuang, David T. (AS); (UTSMC)

    2012-02-27

    The purified mammalian branched-chain {alpha}-ketoacid dehydrogenase complex (BCKDC), which catalyzes the oxidative decarboxylation of branched-chain {alpha}-keto acids, is essentially devoid of the constituent dihydrolipoamide dehydrogenase component (E3). The absence of E3 is associated with the low affinity of the subunit-binding domain of human BCKDC (hSBDb) for hE3. In this work, sequence alignments of hSBDb with the E3-binding domain (E3BD) of the mammalian pyruvate dehydrogenase complex show that hSBDb has an arginine at position 118, where E3BD features an asparagine. Substitution of Arg-118 with an asparagine increases the binding affinity of the R118N hSBDb variant (designated hSBDb*) for hE3 by nearly 2 orders of magnitude. The enthalpy of the binding reaction changes from endothermic with the wild-type hSBDb to exothermic with the hSBDb* variant. This higher affinity interaction allowed the determination of the crystal structure of the hE3/hSBDb* complex to 2.4-{angstrom} resolution. The structure showed that the presence of Arg-118 poses a unique, possibly steric and/or electrostatic incompatibility that could impede E3 interactions with the wild-type hSBDb. Compared with the E3/E3BD structure, the hE3/hSBDb* structure has a smaller interfacial area. Solution NMR data corroborated the interactions of hE3 with Arg-118 and Asn-118 in wild-type hSBDb and mutant hSBDb*, respectively. The NMR results also showed that the interface between hSBDb and hE3 does not change significantly from hSBDb to hSBDb*. Taken together, our results represent a starting point for explaining the long standing enigma that the E2b core of the BCKDC binds E3 far more weakly relative to other {alpha}-ketoacid dehydrogenase complexes.

  10. Development of a monoclonal antibody to urinary degradation products from the C-terminal telopeptide alpha 1 chain of type I collagen. Application in an enzyme Immunoassay and comparison to CrossLaps(TM) ELISA

    DEFF Research Database (Denmark)

    C, Fledelius; I, Kolding; P, Quist

    1997-01-01

    A monoclonal antibody MAbA7 was raised against a synthetic peptide having a sequence (EKAHDGGR) specific for a part of the C-telopeptide alpha 1 chain of type I collagen. MAbA7 was labelled with horseradish peroxide and used in a competitive one-step enzyme-linked immunosorbent assay (ELISA) for ...

  11. Tissue-specific expression of the human laminin alpha5-chain, and mapping of the gene to human chromosome 20q13.2-13.3 and to distal mouse chromosome 2 near the locus for the ragged (Ra) mutation

    DEFF Research Database (Denmark)

    Durkin, M E; Loechel, F; Mattei, M G

    1997-01-01

    , heart, lung, skeletal muscle, kidney, and pancreas. The human laminin alpha5-chain gene (LAMA5) was assigned to chromosome 20q13.2-q13.3 by in situ hybridization, and the mouse gene (Lama5) was mapped by linkage analysis to a syntonic region of distal chromosome 2, close to the locus for the ragged (Ra...

  12. QUANTITATION OF DNA TOPOISOMERASE-II-ALPHA MESSENGER-RIBONUCLEIC-ACID LEVELS IN A SMALL-CELL LUNG-CANCER CELL-LINE AND 2 DRUG-RESISTANT SUBLINES USING A POLYMERASE CHAIN REACTION-AIDED TRANSCRIPT TITRATION ASSAY

    NARCIS (Netherlands)

    WITHOFF, S; SMIT, EF; MEERSMA, GJ; van den Berg, Anke; TIMMERBOSSCHA, H; KOK, K; POSTMUS, PE; MULDER, NH; DEVRIES, EGE; BUYS, CHCM

    BACKGROUND: We have modified a polymerase chain reaction (PCR)-aided transcript titration assay (1) in order to allow quantitation of low amounts of DNA topoisomerase II alpha mRNA in small RNA samples. EXPERIMENTAL DESIGN: The titration assay was used to quantitate the amount of DNA topoisomerase

  13. The carbon monoxide derivative of human hemoglobin carrying the double mutation LeuB10-->Tyr and HisE7-->Gln on alpha and beta chains probed by infrared spectroscopy.

    Science.gov (United States)

    Miele, Adriana E; Draghi, Federica; Vallone, Beatrice; Boffi, Alberto

    2002-06-01

    The fine structural properties of the distal heme pocket have been probed by infrared spectroscopy of ferrous carbon monoxy human hemoglobin mutants carrying the mutations LeuB10-->Tyr and HisE7-->Gln on the alpha, beta, and both chains, respectively. The stretching frequency of iron-bound carbon monoxide occurs as a single broad band around 1943 cm(-1) in both the alpha and the beta mutated chains. Such a frequency value indicates that no direct hydrogen bonding exists between the bound CO molecule and the TyrB10 phenolic oxygen, at variance with other naturally occurring TyrB10, GlnE7 nonvertebrate hemoglobins. The rates of carbon monoxide release have been determined for the first time by a Fourier transform infrared spectroscopy stopped-flow technique that allowed us to single out the heterogeneity in the kinetics of CO release in the alpha and beta chains for the mutated proteins and for native HbA. The rates of CO release are 15- to 20-fold faster for the mutated alpha or beta chains with respect to the native ones consistent with the lack of distal stabilization on the iron-bound CO molecule. The present results demonstrate that residues in key topological positions (namely E7 and B10) for the distal steric control of the iron-bound ligand are not interchangeable among hemoglobins from different species.

  14. Cloning, expression, purification and characterization of a single chain variable fragment specific to tumor necrosis factor alpha in Escherichia coli.

    Science.gov (United States)

    Sushma, Krishnan; Vijayalakshmi, Mookambeswaran A; Krishnan, Venkataraman; Satheeshkumar, Padikara Kutty

    2011-12-20

    Anti TNF-α molecules have been used as therapeutic agents in a variety of human diseases such as Rheumatoid arthritis, Ankylosing spondylitis, Chron's diseases, Psoriasis, etc., where high levels of TNF-α plays a destructive role. The limitations of the present TNF-α inhibitors in terms of size, tissue penetration and immunogenicity, etc., provoked the search for small anti TNF-α molecules. In the present study, a single chain variable fragment (ScFv) construct was made from a monoclonal antibody of the class IgG raised against TNF-α was used. The anti TNF-α ScFv was well expressed as soluble form in Escherichia coli BL21 (DE3), which was purified to homogeneity by commercial methacrylate monolith-convective interaction media (CIM) supports using two different chemistries, immobilized metal affinity chromatography (IMAC) with copper ions followed by anion exchange chromatography. The anti TNF-α ScFv found to be inhibiting the TNF-α mediated cytotoxicity in MCF-7 cells with an IC(50) of 8μg. Data presented here are promising and encouraging to further optimize anti TNF-α ScFv production in larger scale with higher recovery at a cheaper price for therapeutic purposes. Copyright © 2011 Elsevier B.V. All rights reserved.

  15. "Alpha decays" of Be-10(Lambda) and B-10(Lambda) hypernuclei on a nuclotron: A clue to some puzzles in nonleptonic processes

    Czech Academy of Sciences Publication Activity Database

    Batusov, Yu.; Lukstins, J.; Majling, Lubomír; Parfenov, AN.

    2005-01-01

    Roč. 36, č. 2 (2005), s. 169-190 ISSN 1063-7796 R&D Projects: GA ČR GA202/02/0930 Institutional research plan: CEZ:AV0Z10480505 Keywords : nonmesonic weak decay * hyperon-nucleon interaction * Lambda-N-interaction Subject RIV: BE - Theoretical Physics Impact factor: 0.505, year: 2005

  16. Relative contribution of the hydrogen 2S two-photon decay and Lyman-alpha escape channels during the epoch of cosmological recombination

    OpenAIRE

    Rubino-Martin, J. A.; Sunyaev, R. A.

    2017-01-01

    We discuss the evolution of the ratio in number of recombinations due to 2s two photon escape and due to the escape of Lyman-$\\alpha$ photons from the resonance during the epoch of cosmological recombination, within the width of the last scattering surface and near its boundaries. We discuss how this ratio evolves in time, and how it defines the profile of the Lyman-$\\alpha$ line in the spectrum of CMB. One of the key reasons for explaining its time dependence is the strong overpopulation of ...

  17. Frequent expression loss of Inter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multiple human solid tumors: A systematic expression analysis

    International Nuclear Information System (INIS)

    Hamm, Alexander; Knuechel, Ruth; Dahl, Edgar; Veeck, Juergen; Bektas, Nuran; Wild, Peter J; Hartmann, Arndt; Heindrichs, Uwe; Kristiansen, Glen; Werbowetski-Ogilvie, Tamra; Del Maestro, Rolando

    2008-01-01

    The inter-alpha-trypsin inhibitors (ITI) are a family of plasma protease inhibitors, assembled from a light chain – bikunin, encoded by AMBP – and five homologous heavy chains (encoded by ITIH1, ITIH2, ITIH3, ITIH4, and ITIH5), contributing to extracellular matrix stability by covalent linkage to hyaluronan. So far, ITIH molecules have been shown to play a particularly important role in inflammation and carcinogenesis. We systematically investigated differential gene expression of the ITIH gene family, as well as AMBP and the interacting partner TNFAIP6 in 13 different human tumor entities (of breast, endometrium, ovary, cervix, stomach, small intestine, colon, rectum, lung, thyroid, prostate, kidney, and pancreas) using cDNA dot blot analysis (Cancer Profiling Array, CPA), semiquantitative RT-PCR and immunohistochemistry. We found that ITIH genes are clearly downregulated in multiple human solid tumors, including breast, colon and lung cancer. Thus, ITIH genes may represent a family of putative tumor suppressor genes that should be analyzed in greater detail in the future. For an initial detailed analysis we chose ITIH2 expression in human breast cancer. Loss of ITIH2 expression in 70% of cases (n = 50, CPA) could be confirmed by real-time PCR in an additional set of breast cancers (n = 36). Next we studied ITIH2 expression on the protein level by analyzing a comprehensive tissue micro array including 185 invasive breast cancer specimens. We found a strong correlation (p < 0.001) between ITIH2 expression and estrogen receptor (ER) expression indicating that ER may be involved in the regulation of this ECM molecule. Altogether, this is the first systematic analysis on the differential expression of ITIH genes in human cancer, showing frequent downregulation that may be associated with initiation and/or progression of these malignancies

  18. Study of the excited levels of 233{sup P}a by the 237{sup N}p alpha decay; Estudio de los niveles excitados en el 233{sup P}a por la desintegracion alfa del 237{sup N}p

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, J.; Gaeta, R.; Vano, E.; Los Arcos, J. M.

    1978-07-01

    The excited levels in 233{sup P}a following the 237{sup N}p alpha decay have been studied, by performing different experiences to complete available data and supply new information. Thus, two direct alpha spectrum measurement, one alpha-gamma bidimensional coincidence experiment, three gamma-gamma and gamma-X ray coincidences and some other measurements of the gamma spectrum, direct and coincident with alpha-particles have been made. These last experiences have allowed to obviate usual radiochemical separation methods, the 233{sup P}a radioactive descendent interferences being eliminated by means of the coincidence technic. As a result, a primary decay scheme has been elaborated, including 15 new gamma transitions and two new levels, not observed in the most recent works. (Author) 60 refs.

  19. Ginger extract mitigates ethanol-induced changes of alpha and beta - myosin heavy chain isoforms gene expression and oxidative stress in the heart of male wistar rats.

    Science.gov (United States)

    Shirpoor, Alireza; Zerehpoosh, Mitra; Ansari, Mohammad Hasan Khadem; Kheradmand, Fatemeh; Rasmi, Yousef

    2017-09-01

    The association between ethanol consumption and heart abnormalities, such as chamber dilation, myocyte damage, ventricular hypertrophy, and hypertension is well known. However, underlying molecular mediators involved in ethanol-induced heart abnormalities remain elusive. The aim of this study was to investigate the effect of chronic ethanol exposure on alpha and beta - myosin heavy chain (MHC) isoforms gene expression transition and oxidative stress in rats' heart. It was also planned to find out whether ginger extract mitigated the abnormalities induced by ethanol in rats' heart. Male wistar rats were divided into three groups of eight animals as follows: Control, ethanol, and ginger extract treated ethanolic (GETE) groups. After six weeks of treatment, the results revealed a significant increase in the β-MHC gene expression, 8- OHdG amount, and NADPH oxidase level. Furthermore, a significant decrease in the ratio of α-MHC/β-MHC gene expression to the amount of paraoxonase enzyme in the ethanol group compared to the control group was found. The consumption of Ginger extract along with ethanol ameliorated the changes in MHC isoforms gene expression and reduced the elevated amount of 8-OHdG and NADPH oxidase. Moreover, compared to the consumption of ethanol alone, it increased the paraoxonase level significantly. These findings indicate that ethanol-induced heart abnormalities may in part be associated with MHC isoforms changes mediated by oxidative stress, and that these effects can be alleviated by using ginger extract as an antioxidant molecule. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Proteomic demonstration of the recurrent presence of inter-alpha-inhibitor H4 heavy-chain during aspergillosis induced in an animal model.

    Science.gov (United States)

    Desoubeaux, Guillaume; Jourdan, Marie-Lise; Valera, Lionel; Jardin, Bénédicte; Hem, Sonia; Caille, Agnès; Cormier, Bénédicte; Marchand-Adam, Sylvain; Bailly, Éric; Diot, Patrice; Chandenier, Jacques

    2014-05-01

    Invasive pulmonary aspergillosis remains a matter of great concern in oncology/haematology, intensive care units and organ transplantation departments. Despite the availability of various diagnostic tools with attractive features, new markers of infection are required for better medical care. We therefore looked for potential pulmonary biomarkers of aspergillosis, by carrying out two-dimensional (2D) gel electrophoresis comparing the proteomes of bronchial-alveolar lavage fluids (BALF) from infected rats and from control rats presenting non-specific inflammation, both immunocompromised. A bioinformatic analysis of the 2D-maps revealed significant differences in the abundance of 20 protein spots (ANOVA P-valuevalue0.8). One of these proteins, identified by mass spectrometry, was considered of potential interest: inter-alpha-inhibitor H4 heavy-chain (ITIH4), characterised for the first time in this infectious context. Western blotting confirmed its overabundance in all infected BALF, particularly at early stages of murine aspergillosis. Further investigations were carried on rat serum, and confirmed that ITIH4 levels increased during experimental aspergillosis. Preliminary results in human samples strengthened this trend. To our knowledge, this is the first description of the involvement of ITIH4 in aspergillosis. Copyright © 2013 Elsevier GmbH. All rights reserved.

  1. Expression of anti-tumor necrosis factor alpha (TNFα) single-chain variable fragment (scFv) in Spirodela punctata plants transformed with Agrobacterium tumefaciens.

    Science.gov (United States)

    Balaji, Parthasarathy; Satheeshkumar, P K; Venkataraman, Krishnan; Vijayalakshmi, M A

    2016-05-01

    Therapeutic antibodies against tumor necrosis factor alpha (TNFα) have been considered effective for some of the autoimmune diseases such as rheumatoid arthritis, Crohn's diseases, and so on. But associated limitations of the current therapeutics in terms of cost, availability, and immunogenicity have necessitated the need for alternative candidates. Single-chain variable fragment (scFv) can negate the limitations tagged with the anti-TNFα therapeutics to a greater extent. In the present study, Spirodela punctata plants were transformed with anti-TNFα through in planta transformation using Agrobacterium tumefaciens strain, EHA105. Instead of cefotaxime, garlic extract (1 mg/mL) was used to remove the agrobacterial cells after cocultivation. To the best of our knowledge, this report shows for the first time the application of plant extracts in transgenic plant development. 95% of the plants survived screening under hygromycin. ScFv cDNA integration in the plant genomic DNA was confirmed at the molecular level by PCR. The transgenic protein expression was followed up to 10 months. Expression of scFv was confirmed by immunodot blot. Protein expression levels of up to 6.3% of total soluble protein were observed. β-Glucuronidase and green fluorescent protein expressions were also detected in the antibiotic resistant plants. The paper shows the generation of transgenic Spirodela punctuata plants through in planta transformation. © 2015 International Union of Biochemistry and Molecular Biology, Inc.

  2. SNP analysis of the inter-alpha-trypsin inhibitor family heavy chain-related protein (IHRP gene by a fluorescence-adapted SSCP method

    Directory of Open Access Journals (Sweden)

    Taniyama Matsuo

    2002-07-01

    Full Text Available Abstract Background Single-nucleotide polymorphisms (SNPs are considered to be useful polymorphic markers for genetic studies of polygenic traits. Single-stranded conformational polymorphism (SSCP analysis has been widely applied to detect SNPs, including point mutations in cancer and congenital diseases. In this study, we describe an application of the fluorescent labeling of PCR fragments using a fluorescent-adapted primer for SSCP analysis as a novel method. Methods Single-nucleotide polymorphisms (SNPs of the inter-alpha-trypsin inhibitor family heavy chain-related protein (IHRP gene were analyzed using a fluorescence-adapted SSCP method. The method was constructed from two procedures: 1 a fluorescent labeling reaction of PCR fragments using fluorescence-adapted primers in a single tube, and 2 electrophoresis on a non-denaturing polyacrylamide gel. Results This method was more economical and convenient than the single-stranded conformational polymorphism (SSCP methods previously reported in the detection of the labeled fragments obtained. In this study, eight SNPs of the IHRP gene were detected by the fluorescence-adapted SSCP. One of the SNPs was a new SNP resulting in an amino acid substitution, while the other SNPs have already been reported in the public databases. Six SNPs of the IHRP were associated with two haplotypes. Conclusions The fluorescence-adapted SSCP was useful for detecting and genotyping SNPs.

  3. The thiol proteinases from the latex of Carica papaya L. IV. Proteolytic specificities of chymopapain and papaya proteinase omega determined by digestion of alpha-globin chains.

    Science.gov (United States)

    Jacquet, A; Kleinschmidt, T; Dubois, T; Schnek, A G; Looze, Y; Braunitzer, G

    1989-08-01

    The proteolytic specificities of chymopapain and papaya proteinase omega were investigated by using the alpha-chains of manatee and mole haemoglobin, whose primary structures are known, as substrates. The resulting peptides from each enzymatic cleavage were isolated by gel filtration on Sephadex G-25, followed by reversed-phase HPLC of the separated peaks and, in some cases, further purified by preparative thin-layer electrophoresis. The purified peptides were then identified on the basis of their amino-acid composition. The proteolytic specificities of chymopapain and papaya proteinase omega, deduced from the experimental cleavage patterns, are compared to that of papain. As in the case of papain, the specificity-determining factor is the amino-acid residue of the substrate that will be bound in subsite S2 (the next but one from the scissible bond). Aromatic residues in this position, preferred by papain, are not important for chymopapain and papaya proteinase omega. Cleavages preferentially occur when S2 is occupied by leucine, valine or threonine. For chymopapain, proline in position S2 also causes cleavage.

  4. On the claim of modulations in radon decay and their association with solar rotation

    Science.gov (United States)

    Pommé, S.; Lutter, G.; Marouli, M.; Kossert, K.; Nähle, O.

    2018-01-01

    Claims were made by Sturrock et al. that radioactive decay can be induced by interaction of the nucleus with solar neutrinos and that cyclic modulations in decay rates are indicative of the dynamics of the solar interior. They analysed a series of measurements of gamma radiation associated with the emanation and decay of radon in a sealed container at the Geological Survey of Israel (GSI) laboratory. The integral count rates in the NaI detector showed strong variations in time of year and time of day. From time-series analysis, Sturrock et al. claim the presence of small oscillations at frequencies in a range between 7.4 a-1 and 12.5 a-1, which they speculatively associated with rotational influence on the solar neutrino flux. In this work, it is argued that the GSI radon measurements are unsuited for studying the variability of decay constants, because the data are strongly influenced by environmental conditions, such as solar irradiance and rainfall. At the JRC and PTB, decay rate measurements of the radon decay chain were performed with ionisation chambers, gamma-ray spectrometers and an alpha spectrometer. No deviation from the exponential-decay law was observed. The existence of cyclic variations in the decay constants is refuted, as well as the concept of measuring solar rotation through radioactive decay.

  5. Complete amino acid sequence of the human alpha 5 (IV) collagen chain and identification of a single-base mutation in exon 23 converting glycine 521 in the collagenous domain to cysteine in an Alport syndrome patient

    DEFF Research Database (Denmark)

    Zhou, J; Hertz, Jens Michael; Leinonen, A

    1992-01-01

    We have generated and characterized cDNA clones providing the complete amino acid sequence of the human type IV collagen chain whose gene has been shown to be mutated in X chromosome-linked Alport syndrome. The entire translation product has 1,685 amino acid residues. There is a 26-residue signal...... peptide, a 1,430-residue collagenous domain starting with a 14-residue noncollagenous sequence, and a Gly-Xaa-Yaa-repeat sequence interrupted at 22 locations, and a 229-residue carboxyl-terminal noncollagenous domain. The calculated molecular weight of the mature alpha 5(IV) chain is 158,303. Analysis...

  6. A reliable screening test to identify adult carriers of the (--SEA) alpha zero-thalassemia deletion. Detection of embryonic zeta-globin chains by enzyme-linked immunosorbent assay.

    Science.gov (United States)

    Lafferty, J D; Crowther, M A; Waye, J S; Chui, D H

    2000-12-01

    Homozygous (--SEA) alpha zero-thalassemia deletion, the cause of up to 80% of fetal hydrops in Southeast Asia, is encountered in many other countries. Heterozygous carrier rates of the deletion in Southeast Asian populations range from 4% to 14%. The laboratory screening for adult carriers of (--SEA) and other alpha zero-thalassemia deletions currently rests primarily with microscopic detection of hemoglobin H inclusion bodies within erythrocytes (Hb H screen). This test is laborious and observer dependent and has poor sensitivity. We assessed a colorimetric enzyme-linked immunosorbent assay (ELISA) to detect embryonic zeta-globin chains in adult hemolysates as an alternative to detect (--SEA) alpha zero-thalassemia deletion carriers. Blood samples from 221 adults with a mean corpuscular volume less than 80 micron 3 (80 fL) were studied prospectively by currently accepted hemoglobin screening tests and ELISA. Suspected cases of alpha-thalassemia were confirmed by DNA-based diagnostics. ELISA was highly sensitive (1.0) and specific (0.94) for the detection of adult carriers of (--SEA) alpha zero-thalassemia deletion. The hemoglobin H screen had a sensitivity of 0.47 and specificity of 0.99. The zeta-globin ELISA proved simple to perform, rapid, and applicable to high volume or population-based screening programs.

  7. Decay ring design

    CERN Document Server

    Chancé, A; Bouquerel, E; Hancock, S; Jensen, E

    The study of the neutrino oscillation between its different flavours needs pureand very intense fluxes of high energy, well collimated neutrinos with a welldetermined energy spectrum. A dedicated machine seems to be necessarynowadays to reach the required flux. A new concept based on the β-decayof radioactive ions which were accelerated in an accelerator chain was thenproposed. After ion production, stripping, bunching and acceleration, the unstableions are then stored in a racetrack-shaped superconducting decay ring.Finally, the ions are accumulated in the decay ring until being lost. The incomingbeam is merged to the stored beam by using a specific RF system, whichwill be presented here.We propose here to study some aspects of the decay ring, such as its opticalproperties, its RF system or the management of the losses which occur in thering (mainly by decay or by collimation).

  8. Weak decays

    International Nuclear Information System (INIS)

    Wojcicki, S.

    1978-11-01

    Lectures are given on weak decays from a phenomenological point of view, emphasizing new results and ideas and the relation of recent results to the new standard theoretical model. The general framework within which the weak decay is viewed and relevant fundamental questions, weak decays of noncharmed hadrons, decays of muons and the tau, and the decays of charmed particles are covered. Limitation is made to the discussion of those topics that either have received recent experimental attention or are relevant to the new physics. (JFP) 178 references

  9. Assembly, intracellular processing, and expression at the cell surface of the human alpha beta T cell receptor/CD3 complex. Function of the CD3-zeta chain

    DEFF Research Database (Denmark)

    Geisler, C; Kuhlmann, J; Rubin, B

    1989-01-01

    complex, the role of the CD3 chains for the TCR/CD3 expression have not been experimentally addressed in human T cells. In this study the function of the CD3-zeta chain for the assembly, intracellular processing, and expression of the TCR/CD3 complex in the human leukemic T cell line Jurkat...

  10. Identification cloning and characterization of a branched-chain alpha-keto acid decarboxylase from Lactococcus lactis, involved in flavour formation

    NARCIS (Netherlands)

    Smit, B.A.; Meijer, L.; Engels, W.J.M.; Wouters, J.T.M.; Smit, G.

    2005-01-01

    The biochemical pathway for formation of branched-chain aldehydes, which are important flavor compounds derived from proteins in fermented dairy products, consists of a protease, peptidases, a transaminase, and a branched-chain ¿-keto acid decarboxylase (KdcA). The activity of the latter enzyme has

  11. MHC class II alpha, beta and MHC class II-associated invariant chains from Chinese sturgeon (Acipenser sinensis) and their response to immune stimulation.

    Science.gov (United States)

    Li, Xiuyu; Du, Hejun; Liu, Liu; You, Xiuling; Wu, Mingjiang; Liao, Zhiyong

    2017-11-01

    The major histocompatibility complex class II (MHC II) molecules play a vital role in adaptive immune response through presenting antigenic peptides to CD4 + T lymphocytes. To accomplish this physiologic function, the MHC class II-associated invariant chain interacts with the MHC II α/β subunits and promotes their correct assembly and efficient traffic. Here, we isolated the cDNAs of MHC II α, β and MHC II-associated invariant chains (designated as CsMHC II α, CsMHC II β, and CsMHC II γ) from Chinese sturgeon (Acipenser sinensis). The CsMHC II α, β, and γ mRNAs were widely expressed in Chinese sturgeon, and the highest expression was found in spleen for CsMHC II α and β chains, while in head kidney for CsMHC II γ chain. Stimulation to Chinese sturgeon with inactivated trivalent bacterial vaccine or polyinosinic polycytidylic acid (poly(I:C)) up-regulated the expressions of CsMHC II α, and β mRNAs, and their transcripts were overall more quickly up-regulated by poly(I:C) than by bacterial vaccine. Poly(I:C) induced higher CsMHC II γ expression than bacterial vaccine in intestine and spleen, while lower than bacterial vaccine in head kidney and liver. When co-expressed in mouse dendritic cells, the CsMHC II γ chain bound to both the MHC II α and β chains. Furthermore, the over-expressed CsMHC II γ chain, not CsMHC II α or CsMHC II β chain, activated NF-κB and STAT3 in mouse dendritic cells, and induced TNF-α and IL-6 expressions as well. This activity was nearly abolished by mutation of the Ser29/Ser34 to Ala29/Ala34 in CsMHC II γ. These results suggested that CsMHC II α, β, and γ chains might play important role in immune response to pathogen microbial infection of Chinese sturgeon possibly via a conserved functional mechanism throughout vertebrate evolution, which might contribute to our understanding the immune biology of sturgeons. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Unified approach to alpha decay calculations

    Indian Academy of Sciences (India)

    2014-05-02

    May 2, 2014 ... also being studied using advanced theoretical methods. In the light of these, the .... be ¯h2(l + 1/2)2/(2mr2) to generate the correct behaviour of the wave function near the origin. This term generates a ... 2. WKB method. In solving the Schrödinger equation for the radial wave function Rl(r) it is convenient to.

  13. Workshop on Precision Measurements of $\\alpha_s$

    Energy Technology Data Exchange (ETDEWEB)

    Bethke, Siegfried; /Munich, Max Planck Inst.; Hoang, Andre H.; /Vienna U.; Kluth, Stefan; /Munich, Max Planck Inst.; Schieck, Jochen; /Munich U.; Stewart, Iain W.; Aoki, S.; Beneke, M.; Bethke, S.; Blumlein, J.; Brambilla, N.; Brodsky, S.; /MIT, LNS

    2011-10-01

    These are the proceedings of the Workshop on Precision Measurements of {alpha}{sub s} held at the Max-Planck-Institute for Physics, Munich, February 9-11, 2011. The workshop explored in depth the determination of {alpha}{sub s}(m{sub Z}) in the {ovr MS} scheme from the key categories where high precision measurements are currently being made, including DIS and global PDF fits, {tau}-decays, electro-weak precision observables and Z-decays, event-shapes, and lattice QCD. These proceedings contain a short summary contribution from the speakers, as well as the lists of authors, conveners, participants, and talks.

  14. Decay properties of heavier nuclei and mass formula

    Energy Technology Data Exchange (ETDEWEB)

    Uno, Masahiro [Ministry of Education, Science and Culture, Tokyo (Japan)

    2000-03-01

    The stabilities of heavy nuclei, including super-heavy elements, are governed by alpha decay and fission. Some exotic types of decay, such as heavy cluster decay, which does not occur so frequently as to govern stability, have been also reported. The half-time estimations of various types of decay are reviewed. And the possibility of decay, mainly in case of heavy cluster decay, is discussed with Q-value obtained from mass formulae as well. Some topics concerning other types of exotic decay are presented. Recent trends in the research on mass formula are reviewed from the historical point of view, to get perspectives of future development. (Yamamoto, A.)

  15. Decay properties of heavier nuclei and mass formula

    International Nuclear Information System (INIS)

    Uno, Masahiro

    2000-01-01

    The stabilities of heavy nuclei, including super-heavy elements, are governed by alpha decay and fission. Some exotic types of decay, such as heavy cluster decay, which does not occur so frequently as to govern stability, have been also reported. The half-time estimations of various types of decay are reviewed. And the possibility of decay, mainly in case of heavy cluster decay, is discussed with Q-value obtained from mass formulae as well. Some topics concerning other types of exotic decay are presented. Recent trends in the research on mass formula are reviewed from the historical point of view, to get perspectives of future development. (Yamamoto, A.)

  16. B decays

    CERN Document Server

    Stone, Sheldon

    1994-01-01

    This book reviews the study of b quarks and also looks at the implications of future studies. The most important observations thus far - including measurement of the ""B"" lifetime and observations of b -> u transitions - as well as the more mundane results of hadronic and semileptonic transitions are described in detail by experimentalists who have been closely involved with the measurements. Theoretical progress in understanding b quark decays, including the mechanisms of hadronic and semileptonic decays, are described. Synthesizing the experimental and theoretical information, the authors d

  17. B decays

    CERN Document Server

    Stone, Sheldon

    1992-01-01

    The study of b quarks has now reached a stage where it is useful to review what has been learned so far and also to look at the implications of future studies. The most important observations thus far - measurement of the "B" lifetime, B 0 - B 0 mixing, and the observation of b? u transitions, as well as more mundane results on hadronic and semileptonic transitions - are described in detail by experimentalists who have been closely involved with the measurements. Theoretical progress in understanding b quark decays, including the mechanisms of hadronic and semileptonic decays, are described. S

  18. A Novel Alpha Cardiac Actin (ACTC1) Mutation Mapping to a Domain in Close Contact with Myosin Heavy Chain Leads to a Variety of Congenital Heart Defects, Arrhythmia and Possibly Midline Defects

    Science.gov (United States)

    Augière, Céline; Mégy, Simon; El Malti, Rajae; Boland, Anne; El Zein, Loubna; Verrier, Bernard; Mégarbané, André; Deleuze, Jean-François; Bouvagnet, Patrice

    2015-01-01

    Background A Lebanese Maronite family presented with 13 relatives affected by various congenital heart defects (mainly atrial septal defects), conduction tissue anomalies and midline defects. No mutations were found in GATA4 and NKX2-5. Methods and Results A set of 399 poly(AC) markers was used to perform a linkage analysis which peaked at a 2.98 lod score on the long arm of chromosome 15. The haplotype analysis delineated a 7.7 meganucleotides genomic interval which included the alpha-cardiac actin gene (ACTC1) among 36 other protein coding genes. A heterozygous missense mutation was found (c.251T>C, p.(Met84Thr)) in the ACTC1 gene which changed a methionine residue conserved up to yeast. This mutation was absent from 1000 genomes and exome variant server database but segregated perfectly in this family with the affection status. This mutation and 2 other ACTC1 mutations (p.(Glu101Lys) and p.(Met125Val)) which result also in congenital heart defects are located in a region in close apposition to a myosin heavy chain head region by contrast to 3 other alpha-cardiac actin mutations (p.(Ala297Ser),p.(Asp313His) and p.(Arg314His)) which result in diverse cardiomyopathies and are located in a totally different interaction surface. Conclusions Alpha-cardiac actin mutations lead to congenital heart defects, cardiomyopathies and eventually midline defects. The consequence of an ACTC1 mutation may in part be dependent on the interaction surface between actin and myosin. PMID:26061005

  19. A Novel Alpha Cardiac Actin (ACTC1 Mutation Mapping to a Domain in Close Contact with Myosin Heavy Chain Leads to a Variety of Congenital Heart Defects, Arrhythmia and Possibly Midline Defects.

    Directory of Open Access Journals (Sweden)

    Céline Augière

    Full Text Available A Lebanese Maronite family presented with 13 relatives affected by various congenital heart defects (mainly atrial septal defects, conduction tissue anomalies and midline defects. No mutations were found in GATA4 and NKX2-5.A set of 399 poly(AC markers was used to perform a linkage analysis which peaked at a 2.98 lod score on the long arm of chromosome 15. The haplotype analysis delineated a 7.7 meganucleotides genomic interval which included the alpha-cardiac actin gene (ACTC1 among 36 other protein coding genes. A heterozygous missense mutation was found (c.251T>C, p.(Met84Thr in the ACTC1 gene which changed a methionine residue conserved up to yeast. This mutation was absent from 1000 genomes and exome variant server database but segregated perfectly in this family with the affection status. This mutation and 2 other ACTC1 mutations (p.(Glu101Lys and p.(Met125Val which result also in congenital heart defects are located in a region in close apposition to a myosin heavy chain head region by contrast to 3 other alpha-cardiac actin mutations (p.(Ala297Ser,p.(Asp313His and p.(Arg314His which result in diverse cardiomyopathies and are located in a totally different interaction surface.Alpha-cardiac actin mutations lead to congenital heart defects, cardiomyopathies and eventually midline defects. The consequence of an ACTC1 mutation may in part be dependent on the interaction surface between actin and myosin.

  20. X-linked Alport syndrome associated with a synonymous p.Gly292Gly mutation alters the splicing donor site of the type IV collagen alpha chain 5 gene.

    Science.gov (United States)

    Fu, Xue Jun; Nozu, Kandai; Eguchi, Aya; Nozu, Yoshimi; Morisada, Naoya; Shono, Akemi; Taniguchi-Ikeda, Mariko; Shima, Yuko; Nakanishi, Koichi; Vorechovsky, Igor; Iijima, Kazumoto

    2016-10-01

    X-linked Alport syndrome (XLAS) is a progressive hereditary nephropathy caused by mutations in the type IV collagen alpha chain 5 gene (COL4A5). Although many COL4A5 mutations have previously been identified, pathogenic synonymous mutations have not yet been described. A family with XLAS underwent mutational analyses of COL4A5 by PCR and direct sequencing, as well as transcript analysis of potential splice site mutations. In silico analysis was also conducted to predict the disruption of splicing factor binding sites. Immunohistochemistry (IHC) of kidney biopsies was used to detect α2 and α5 chain expression. We identified a hemizygous point mutation, c.876A>T, in exon 15 of COL4A5 in the proband and his brother, which is predicted to result in a synonymous amino acid change, p.(Gly292Gly). Transcript analysis showed that this mutation potentially altered splicing because it disrupted the splicing factor binding site. The kidney biopsy of the proband showed lamellation of the glomerular basement membrane (GBM), while IHC revealed negative α5(IV) staining in the GBM and Bowman's capsule, which is typical of XLAS. This is the first report of a synonymous COL4A5 substitution being responsible for XLAS. Our findings suggest that transcript analysis should be conducted for the future correct assessment of silent mutations.

  1. Integrability and soliton solutions for an inhomogeneous generalized fourth-order nonlinear Schrödinger equation describing the inhomogeneous alpha helical proteins and Heisenberg ferromagnetic spin chains

    International Nuclear Information System (INIS)

    Wang, Pan; Tian, Bo; Jiang, Yan; Wang, Yu-Feng

    2013-01-01

    For describing the dynamics of alpha helical proteins with internal molecular excitations, nonlinear couplings between lattice vibrations and molecular excitations, and spin excitations in one-dimensional isotropic biquadratic Heisenberg ferromagnetic spin with the octupole–dipole interactions, we consider an inhomogeneous generalized fourth-order nonlinear Schrödinger equation. Based on the Ablowitz–Kaup–Newell–Segur system, infinitely many conservation laws for the equation are derived. Through the auxiliary function, bilinear forms and N-soliton solutions for the equation are obtained. Interactions of solitons are discussed by means of the asymptotic analysis. Effects of linear inhomogeneity on the interactions of solitons are also investigated graphically and analytically. Since the inhomogeneous coefficient of the equation h=α x+β, the soliton takes on the parabolic profile during the evolution. Soliton velocity is related to the parameter α, distance scale coefficient and biquadratic exchange coefficient, but has no relation with the parameter β. Soliton amplitude and width are only related to α. Soliton position is related to β

  2. Development of the DCHAIN-SP code for analyzing decay and build-up characteristics of spallation products

    Energy Technology Data Exchange (ETDEWEB)

    Takada, Hiroshi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Kosako, Kazuaki

    1999-03-01

    For analyzing the decay and build-up characteristics of spallation products, the DCHAIN-SP code has been developed on the basis of the DCHAIN-2 code by revising the decay data and implementing the neutron cross section data. The decay data are newly processed from the data libraries of EAF 3.1, FENDL/D-1 and ENSDF. The neutron cross section data taken from FENDL/A-2 data library are also prepared to take account of the transmutation of nuclides by the neutron field at the produced position. The DCHAIN-SP code solves the time evolution of decay and build-up of nuclides in every decay chain by the Beteman method. The code can estimate the following physical quantities of produced nuclides: inventory, activity, decay heat by the emission of {alpha}, {beta} and {gamma}-rays, and {gamma}-ray energy spectrum, where the nuclide production rate estimated by the nucleon-meson transport code such as NMTC/JAERI97 is used as an input data. This paper describes about the function, the solution model and the database adopted in the code and explains how to use the code. (author)

  3. Decay scheme of the U235

    International Nuclear Information System (INIS)

    Gaeta, R.

    1965-01-01

    A study of the Th 2 31 excited levels from the alpha decay of the U 2 35, is carried out. The alpha particle spectrum was measured by means of a semiconductor counter spectrometer with an effective resolution of 18 keV. Nineteen new lines were identified. The gamma-ray spectrum was measured with thin samples of U 2 35, free from decay products, and in such geometrical conditions, that most of the interference effects were eliminated. The gamma-gamma coincidence spectra have made easier a better knowledge of the transition between the several levels. (Author) 110 refs

  4. JENDL FP decay data file 2000

    Energy Technology Data Exchange (ETDEWEB)

    Katakura, Jun-ichi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Yoshida, Tadashi [Musashi Inst. of Tech., Tokyo (Japan); Oyamatsu, Kazuhiro [Aichi Shukutoku Univ., Nagakute, Aichi (Japan); Tachibana, Takahiro [Waseda Univ., Tokyo (Japan)

    2001-07-01

    A decay data file of fission product (FP) nuclides has been developed for the use in nuclear technology field as one of special purpose files of JENDL (Japanese Evaluated Nuclear Data Library) in the format of ENDF/B and it is called JENDL FP Decay Data File 2000. The file includes the decay data for 1229 fission product nuclides: 142 stable and 1087 unstable nuclides. The data included for a nuclide are decay modes, their Q values and branching ratios, average decay energy values of beta-rays, gamma-rays and alpha-particles and their spectral data. The primary source of the decay data is ENSDF (Evaluated Nuclear Structure Data File), which is the internationally recognized data file of nuclear structure properties. The data in ENSDF, however, cover only measured ones. The data of the short-lived nuclides needed for the application fields such as decay heat prediction are often incomplete or not measured because of their short half-lives. For such nuclides a theoretical model calculation is applied to derive the needed data such as average decay energies and spectral data. The data in JENDL FP Decay Data File 2000 have been tested by summation calculation comparing its results with measured data of decay heat values and aggregate fission product spectra of various fissioning nuclei. The comparison showed good agreement between the calculated results and the measured values. (author)

  5. Measurement of $\\alpha_{s}$ with Radiative Hadronic Events

    CERN Document Server

    Abbiendi, G; Åkesson, P F; Alexander, G; Anagnostou, G; Anderson, K J; Asai, S; Axen, D; Bailey, I; Barberio, E; Barillari, T; Barlow, R J; Batley, R J; Bechtle, P; Behnke, T; Bell, K W; Bell, P J; Bella, G; Bellerive, A; Benelli, G; Bethke, S; Biebel, O; Boeriu, O; Bock, P; Boutemeur, M; Braibant, S; Brown, R M; Burckhart, H J; Campana, S; Capiluppi, P; Carnegie, R K; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Ciocca, C; Csilling, A; Cuffiani, M; Dado, S; Dallavalle, M; de Roeck, A; De Wolf, E A; Desch, K; Dienes, B; Dubbert, J; Duchovni, E; Duckeck, G; Duerdoth, I P; Etzion, E; Fabbri, F; Ferrari, P; Fiedler, F; Fleck, I; Ford, M; Frey, A; Gagnon, P; Gary, J W; Geich-Gimbel, C; Giacomelli, G; Giacomelli, P; Giunta, M; Goldberg, J; Gross, E; Grunhaus, J; Gruwé, M; Sen-Gupta, A; Hajdu, C; Hamann, M; Hanson, G G; Harel, A; Hauschild, M; Hawkes, C M; Hawkings, R; Herten, G; Heuer, R D; Hill, J C; Horváth, D; Igo-Kemenes, P; Ishii, K; Jeremie, H; Jovanovic, P; Junk, T R; Kanzaki, J; Karlen, D; Kawagoe, K; Kawamoto, T; Keeler, R K; Kellogg, R G; Kennedy, B W; Kluth, S; Kobayashi, T; Kobel, M; Komamiya, S; Kramer, T; Krasznahorkays, A Jr; Krieger, P; Von Krogh, J; Kühl, T; Kupper, M; Lafferty, G D; Landsman, H; Lanske, D; Lellouch, D; Letts, J; Levinson, L; Lillich, J; Lloyd, S L; Loebinger, F K; Lü, J; Ludwig, A; Ludwig, J; Mader, W; Marcellini, S; Martin, A J; Mashimo, T; Mättig, P; McKenna, J; McPherson, R A; Meijers, F; Menges, W; Merritt, F S; Mes, H; Meyer, N; Michelini, A; Mihara, S; Mikenberg, G; Miller, D J; Mohr, W; Mori, T; Mutter, A; Nagai, K; Nakamura, I; Nanjo, H; Neal, H A; O'Neale, S W; Oh, A; Oreglia, M J; Orito, S; Pahl, C; Pásztor, G; Pater, J R; Pilcher, J E; Pinfold, J L; Plane, D E; Pooth, O; Przybycien, M; Quadt, A; Rabbertz, K; Rembser, C; Renkel, P; Roney, J M; Rossi, A M; Rozen, Y; Runge, K; Sachs, K; Saeki, T; Sarkisyan-Grinbaum, E; Schaile, A D; Schaile, O; Scharff-Hansen, P; Schiecks, J; Schörner-Sadenius, T; Schröder, M; Schumacher, M; Seuster, R; Shears, T G; Shen, B C; Sherwood, P; Skuja, A; Smith, A M; Sobie, R J; Söldner-Rembold, S; Spanó, F; Stahl, A; Strom, D; Ströhmer, R; Tarem, S; Tasevsky, M; Teuscher, R; Thomson, M A; Torrence, E; Toya, D; Trigger, I; Trócsányi, Z L; Tsur, E; Turner-Watson, M F; Ueda, I; Ujvári, B; Vollmer, C F; Vannerem, P; Vertesi, R; Verzocchi, M; Voss, H; Vossebeld, J; Ward, C P; Ward, D R; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wengler, T; Wermes, N; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Zer-Zion, D; Zivkovic, L

    2008-01-01

    Hadronic final states with a hard isolated photon are studied using data taken at centre-of-mass energies around the mass of the Z0 boson with the OPAL detector at LEP. The strong coupling alpha S is extracted by comparing data and QCD predictions for event shape observables at average reduced centre-of-mass energies ranging from 24 GeV to 78 GeV, and the energy dependence of alpha S is studied. Our results are consistent with the running of alpha S as predicted by QCD and show that within the uncertainties of our analysis event shapes in hadronic Z0 decays with hard and isolated photon radiation can be described by QCD at reduced centre-of-mass energies. Combining all values from different event shape observables and energies gives alpha S (Mz)=0.1182 pm 0.0015(stat.) pm 0.0101(syst.).

  6. Maple syrup urine disease: The E1{beta} gene of human branched-chain {alpha}-ketoacid dehydrogenase complex has 11 rather than 10 exons, and the 3{prime} UTR in one of the two E1{beta} mRNAs arises from intronic sequences

    Energy Technology Data Exchange (ETDEWEB)

    Chuang, J.L.; Chuang, D.T.; Cox, R.P. [Univ. of Texas Southwestern Medical Center, Dallas, TX (United States)

    1996-06-01

    Maple syrup urine disease (MSUD) or branched-chain ketoaciduria is caused by a deficiency in the mitochondrial branched-chain {alpha}-ketoacid dehydrogenase (BCKAD) complex. The clinical manifestations are characterized by accumulation of branched chain amino and {alpha}-ketoacids, which leads to severe cerebral edema with seizures, ketoacidosis, and mental retardation. The BCKAD complex comprises three catalytic components, i.e., a decarboxylase (E1) consisting of two E1{alpha} (M{sub r} = 46,000) and two E1{Beta} (M{sub r} = 37,500) subunits, a transacylase (E2) that contains 24 lipoic acid-bearing subunits, and a dehydrogenase (E3), which is a homodimeric flavoprotein. MSUD is genetically heterogeneous, since mutations in the E1{alpha} subunit (type IA MSUD), the E1{Beta} subunit (type IB), the E2 subunit (type II) and the E3 subunit (type III) have been described. The functional consequences of certain mutations in the BCKAD complex have been studied. 23 refs., 3 figs.

  7. C4BPAL1, a member of the human regulator of complement activation (RCA) gene cluster that resulted from the duplication of the gene coding for the [alpha]-chain of C4b-binding protein

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez-Corral, P.; Pardo-Manuel de Villena, F.; Rey-Campos, J.; Rodriguez de Cordoba, S. (Unidad de Immunologia, Madrid (Spain))

    1993-07-01

    The regulator of complement activation (RCA) gene cluster evolved by multiple gene duplications to produce a family of genes coding for proteins that collectively control the activation of the complement system. The authors report here the characterization of C4BPAL1, a member of the human RCA gene cluster that arose from the duplication of the C4BPA gene after the separation of rodent and primate lineages. C4BPAL1 maps 20 kb downstream of the C4BPA gene and is in the same 5[prime] to 3[prime] orientation found for all RCA genes characterized thus far. It includes nine exon-like regions homologous to exons 2-8, 11, and 12 of the C4BPA gene. Analysis of the C4BPAL1 sequence suggests that it is currently a pseudogene in humans. However, comparisons between C4BPAL1 and the human and murine C4BPA genes show sequence conservation, which strongly suggests that, for a long period of time, C4BPAL1 has been a functional gene coding for a protein with structural requirements similar to those of the [alpha]-chain of C4b-binding protein. 50 refs., 5 figs., 1 tab.

  8. Inducible knockout of the interleukin-2 receptor alpha chain: expression of the high-affinity IL-2 receptor is not required for the in vitro growth of HTLV-I-transformed cell lines.

    Science.gov (United States)

    Richardson, J H; Waldmann, T A; Sodroski, J G; Marasco, W A

    1997-10-27

    Adult T cell leukemia (ATL) is an aggressive malignancy that is associated with HTLV-I infection and characterized by constitutive expression of the high-affinity interleukin-2 receptor. The alpha subunit of the high-affinity receptor (IL-2Ralpha), which is normally present only on activated T cells, is specifically upregulated by HTLV-I and constitutively expressed on fresh leukemic cells from ATL patients as well as cell lines transformed by HTLV-I in vitro. Here we directly address the functional significance of IL-2Ralpha expression in HTLV-I transformed cell lines by using an endoplasmic reticulum-targeted single-chain antibody to inhibit the cell surface expression of IL-2Ralpha. Using constitutive and tetracycline-repressible systems to express the ER-targeted antibody against IL-2Ralpha, we have reduced cell surface expression of IL-2Ralpha by more that 2 logs of mean fluorescence intensity to virtually undetectable levels in the IL-2-independent HTLV-I-transformed cell lines C8166-45 and HUT102. No toxicity was associated with the intracellular retention of IL-2Ralpha, and the growth rate of the IL-2Ralpha-negative cells was in each case comparable to that of the parental cell line. We conclude that cell surface expression of IL-2Ralpha is dispensable for the in vitro growth of these HTLV-I-transformed cells. Copyright 1997 Academic Press.

  9. Removal of round off errors in the matrix exponential method for solving the heavy nuclide chain

    International Nuclear Information System (INIS)

    Lee, Hyun Chul; Noh, Jae Man; Joo, Hyung Kook

    2005-01-01

    Many nodal codes for core simulation adopt the micro-depletion procedure for the depletion analysis. Unlike the macro-depletion procedure, the microdepletion procedure uses micro-cross sections and number densities of important nuclides to generate the macro cross section of a spatial calculational node. Therefore, it needs to solve the chain equations of the nuclides of interest to obtain their number densities. There are several methods such as the matrix exponential method (MEM) and the chain linearization method (CLM) for solving the nuclide chain equations. The former solves chain equations exactly even when the cycles that come from the alpha decay exist in the chain while the latter solves the chain approximately when the cycles exist in the chain. The former has another advantage over the latter. Many nodal codes for depletion analysis, such as MASTER, solve only the hard coded nuclide chains with the CLM. Therefore, if we want to extend the chain by adding some more nuclides to the chain, we have to modify the source code. In contrast, we can extend the chain just by modifying the input in the MEM because it is easy to implement the MEM solver for solving an arbitrary nuclide chain. In spite of these advantages of the MEM, many nodal codes adopt the chain linearization because the former has a large round off error when the flux level is very high or short lived or strong absorber nuclides exist in the chain. In this paper, we propose a new technique to remove the round off errors in the MEM and we compared the performance of the two methods

  10. Comprehensive decay law for emission of charged particles and ...

    Indian Academy of Sciences (India)

    2014-04-07

    Apr 7, 2014 ... the case of alpha, cluster and proton decays are presented together. It is seen that, all of them fall in a single straight line with a common value for slope and intercept. This shows how the decays of charged particles of any Z values from heavy nuclei are governed by a single rule of law, namely, the linear ...

  11. On the decay properties of sup 2 sup 6 sup 9 Hs and indications for the new nuclide sup 2 sup 7 sup 0 Hs

    CERN Document Server

    Türler, A; Gäggeler, H W; Kirbach, U W; Ginter, T N; Gregorich, K E; Lee, D M; Yakushev, A B; Schädel, M; Brüchle, W; Jäger, E; Dressler, R; Eichler, B; Eichler, R; Glaus, F; Jost, D T; Eberhardt, K; Hoffman, D C; Nitsche, H; Patin, J B; Pershina, V; Piguet, D; Qin, Z; Schausten, B; Schimpf, E; Schoett, H J; Soverna, S; Sudowe, R; Thörle, P; Timokhin, S N; Trautmann, N; Vahle, A; Wirth, G; Zielinski, P M

    2003-01-01

    In bombardments of sup 2 sup 4 sup 8 Cm with 143.7-146.8 MeV sup 2 sup 6 Mg ions the nuclides sup 2 sup 6 sup 9 Hs and presumably sup 2 sup 7 sup 0 Hs were produced. After chemical isolation, Hs atoms were identified by observing genetically linked nuclear-decay chains. Three chains originating from sup 2 sup 6 sup 9 Hs confirmed the decay properties observed previously in the decay of sup 2 sup 7 sup 7 112. Two chains exhibited the characteristics expected for the new nuclide sup 2 sup 7 sup 0 Hs, which was predicted to be a deformed ''doubly magic'' nucleus. From the measured E subalpha =9.16 sup + sup 0 sup . sup 0 sup 7 sub - sub 0 sub . sub 0 sub 3 MeV an alpha-decay half-life of 3.6 sup + sup 0 sup . sup 8 sub - sub 1 sub . sub 4 s was estimated. (orig.)

  12. Alpha-emitting isotopes and chromium in a coastal California aquifer

    Science.gov (United States)

    Densmore, Jill N.; Izbicki, John A.; Murtaugh, Joseph M.; Swarzenski, Peter W.; Bullen, Thomas D.

    2014-01-01

    The unadjusted 72-h gross alpha activities in water from two wells completed in marine and alluvial deposits in a coastal southern California aquifer 40 km north of San Diego were 15 and 25 picoCuries per liter (pCi/L). Although activities were below the Maximum Contaminant Level (MCL) of 15 pCi/L, when adjusted for uranium activity; there is concern that new wells in the area may exceed MCLs, or that future regulations may limit water use from the wells. Coupled well-bore flow and depth-dependent water-quality data collected from the wells in 2011 (with analyses for isotopes within the uranium, actinium, and thorium decay-chains) show gross alpha activity in marine deposits is associated with decay of naturally-occurring 238U and its daughter 234U. Radon activities in marine deposits were as high as 2230 pCi/L. In contrast, gross alpha activities in overlying alluvium within the Piedra de Lumbre watershed, eroded from the nearby San Onofre Hills, were associated with decay of 232Th, including its daughter 224Ra. Radon activities in alluvium from Piedra de Lumbre of 450 pCi/L were lower than in marine deposits. Chromium VI concentrations in marine deposits were less than the California MCL of 10 μg/L (effective July 1, 2014) but δ53Cr compositions were near zero and within reported ranges for anthropogenic chromium. Alluvial deposits from the nearby Las Flores watershed, which drains a larger area having diverse geology, has low alpha activities and chromium as a result of geologic and geochemical conditions and may be more promising for future water-supply development.

  13. A new alpha(0)-thalassemia deletion found in a Dutch family (--(AW)).

    NARCIS (Netherlands)

    Phylipsen, M.; Vogelaar, I.P.; Schaap, R.A.; Arkesteijn, S.G.; Boxma, G.L.; Helden, W.C. van; Wildschut, I.C.; Bruin-Roest, A.C. de; Giordano, P.C.; Harteveld, C.L.

    2010-01-01

    Alpha-thalassemia is an inherited hemoglobin disorder characterized by a microcytic hypochromic anemia caused by a quantitative reduction of the alpha-globin chain. The majority of the alpha-thalassemias is caused by deletions in the alpha-globin gene cluster. A deletion in the alpha-globin gene

  14. Determination of the Dalitz-plot parameter {alpha} for the decay {eta}{yields}3{pi}{sup 0} with the Crystal Ball at MAMI; Bestimmung des Dalitz-Plot-Parameters {alpha} fuer den Zerfall {eta} {yields} 3{pi}{sup 0} mit dem Crystal Ball am MAMI

    Energy Technology Data Exchange (ETDEWEB)

    Unverzagt, Marc

    2008-05-26

    In order to determine the Dalitz-plot parameter {alpha} experiments were evaluated, Which were performed with the Crystal Ball/TAPS facility at the accelerator MAMI of the Institute for Nuclear Physics at the Johannes Gutenberg University in Mainz in the years 2004 and 2005. {eta} mesons wer produced via the reaction {gamma}p{yields}{eta}p. From four different analyses the following four in this thesis determined Dalitz-plot parameters with the given statistics resulted: {eta} without proton: {alpha}=-0.0314{+-}0.0013{sub -0.0014}{sup +0.0017} (1.1.10{sup 6} events), {eta} with proton: {alpha}=-0.0338{+-}0.0020{sub -0.0022}{sup +0.0019} (4.2.10{sup 5} events), {delta}{sup +} magnetic dipole moment without proton: {alpha}=-0.0277{+-}0.0013{sub -0.0019}{sup +0.0014} (7.1.10{sup 5} events), {delta}{sup +} magnetic dipole moment with proton: {alpha}=-0.0272{+-}0.0019{sub -0.0043}{sup +0.0022} (3.1.10{sup 5} events).

  15. Buffett's Alpha

    DEFF Research Database (Denmark)

    Frazzini, Andrea; Kabiller, David; Heje Pedersen, Lasse

    Berkshire Hathaway has realized a Sharpe ratio of 0.76, higher than any other stock or mutual fund with a history of more than 30 years, and Berkshire has a significant alpha to traditional risk factors. However, we find that the alpha becomes insignificant when controlling for exposures to Betting-Against-Beta...... in publicly traded stocks versus wholly-owned private companies, we find that the former performs the best, suggesting that Buffett's returns are more due to stock selection than to his effect on management. These results have broad implications for market efficiency and the implementability of academic...

  16. Measurement of the angle alpha at BABAR

    Energy Technology Data Exchange (ETDEWEB)

    Perez, A.; /Orsay, LAL

    2009-06-25

    The authors present recent measurements of the CKM angle {alpha} using data collected by the BABAR detector at the PEP-II asymmetric-energy e{sup +}e{sup -} collider at the SLAC National Accelerator Laboratory, operating at the {Upsilon}(4S) resonance. They present constraints on {alpha} from B {yields} {pi}{pi}, B {yields} {rho}{rho} and B {yields} {rho}{pi} decays.

  17. Production of $\\Sigma^{0}$ and $\\Omega^{-}$ in Z decays

    CERN Document Server

    Adam, W; Agasi, E; Ajinenko, I; Aleksan, Roy; Alekseev, G D; Alemany, R; Allport, P P; Almehed, S; Amaldi, Ugo; Amato, S; Andreazza, A; Andrieux, M L; Antilogus, P; Apel, W D; Arnoud, Y; Åsman, B; Augustin, J E; Augustinus, A; Baillon, Paul; Bambade, P; Barão, F; Barate, R; Barbi, M S; Bardin, Dimitri Yuri; Baroncelli, A; Bärring, O; Barrio, J A; Bartl, Walter; Bates, M J; Battaglia, Marco; Baubillier, M; Baudot, J; Becks, K H; Begalli, M; Beillière, P; Belokopytov, Yu A; Belous, K S; Benvenuti, Alberto C; Berggren, M; Bertrand, D; Bianchi, F; Bigi, M; Bilenky, S M; Billoir, P; Bloch, D; Blume, M; Blyth, S; Bolognese, T; Bonesini, M; Bonivento, W; Booth, P S L; Borisov, G; Bosio, C; Bosworth, S; Botner, O; Boudinov, E; Bouquet, B; Bourdarios, C; Bowcock, T J V; Bozzo, M; Branchini, P; Brand, K D; Brenke, T; Brenner, R A; Bricman, C; Brillault, L; Brown, R C A; Brückman, P; Brunet, J M; Bugge, L; Buran, T; Burgsmüller, T; Buschmann, P; Buys, A; Cabrera, S; Caccia, M; Calvi, M; Camacho-Rozas, A J; Camporesi, T; Canale, V; Canepa, M; Cankocak, K; Cao, F; Carena, F; Carroll, L; Caso, Carlo; Castillo-Gimenez, M V; Cattai, A; Cavallo, F R; Cerrito, L; Chabaud, V; Chapkin, M M; Charpentier, P; Chaussard, L; Chauveau, J; Checchia, P; Chelkov, G A; Chen, M; Chierici, R; Chliapnikov, P V; Chochula, P; Chorowicz, V; Chudoba, J; Cindro, V; Collins, P; Contreras, J L; Contri, R; Cortina, E; Cosme, G; Cossutti, F; Crawley, H B; Crennell, D J; Crosetti, G; Cuevas-Maestro, J; Czellar, S; Dahl-Jensen, Erik; Dahm, J; D'Almagne, B; Dam, M; Damgaard, G; Dauncey, P D; Davenport, Martyn; Da Silva, W; Defoix, C; Deghorain, A; Della Ricca, G; Delpierre, P A; Demaria, N; De Angelis, A; de Boer, Wim; De Brabandere, S; De Clercq, C; La Vaissière, C de; De Lotto, B; De Min, A; De Paula, L S; De Saint-Jean, C; Dijkstra, H; Di Ciaccio, Lucia; Djama, F; Dolbeau, J; Dönszelmann, M; Doroba, K; Dracos, M; Drees, J; Drees, K A; Dris, M; Dufour, Y; Edsall, D M; Ehret, R; Eigen, G; Ekelöf, T J C; Ekspong, Gösta; Elsing, M; Engel, J P; Ershaidat, N; Erzen, B; Espirito-Santo, M C; Falk, E; Fassouliotis, D; Feindt, Michael; Ferrer, A; Filippas-Tassos, A; Firestone, A; Fischer, P A; Föth, H; Fokitis, E; Fontanelli, F; Formenti, F; Franek, B J; Frenkiel, P; Fries, D E C; Frodesen, A G; Frühwirth, R; Fulda-Quenzer, F; Fuster, J A; Galloni, A; Gamba, D; Gandelman, M; García, C; García, J; Gaspar, C; Gasparini, U; Gavillet, P; Gazis, E N; Gelé, D; Gerber, J P; Gerdyukov, L N; Gibbs, M; Gokieli, R; Golob, B; Gopal, Gian P; Gorn, L; Górski, M; Guz, Yu; Gracco, Valerio; Graziani, E; Grosdidier, G; Grzelak, K; Gumenyuk, S A; Gunnarsson, P; Günther, M; Guy, J; Hahn, F; Hahn, S; Hallgren, A; Hamacher, K; Hao, W; Harris, F J; Hedberg, V; Henriques, R P; Hernández, J J; Herquet, P; Herr, H; Hessing, T L; Higón, E; Hilke, Hans Jürgen; Hill, T S; Holmgren, S O; Holt, P J; Holthuizen, D J; Hoorelbeke, S; Houlden, M A; Hrubec, Josef; Huet, K; Hultqvist, K; Jackson, J N; Jacobsson, R; Jalocha, P; Janik, R; Jarlskog, C; Jarlskog, G; Jarry, P; Jean-Marie, B; Johansson, E K; Jönsson, L B; Jönsson, P E; Joram, Christian; Juillot, P; Kaiser, M; Kapusta, F; Karafasoulis, K; Karlsson, M; Karvelas, E; Katsanevas, S; Katsoufis, E C; Keränen, R; Khomenko, B A; Khovanskii, N N; King, B J; Kjaer, N J; Klein, H; Klovning, A; Kluit, P M; Köne, B; Kokkinias, P; Koratzinos, M; Korcyl, K; Kostyukhin, V; Kourkoumelis, C; Kuznetsov, O; Kramer, P H; Krammer, Manfred; Kreuter, C; Kronkvist, I J; Krumshtein, Z; Krupinski, W; Kubinec, P; Kucewicz, W; Kurvinen, K L; Lacasta, C; Laktineh, I; Lamblot, S; Lamsa, J; Lanceri, L; Lane, D W; Langefeld, P; Last, I; Laugier, J P; Lauhakangas, R; Leder, Gerhard; Ledroit, F; Lefébure, V; Legan, C K; Leitner, R; Lemoigne, Y; Lemonne, J; Lenzen, Georg; Lepeltier, V; Lesiak, T; Liko, D; Lindner, R; Lipniacka, A; Lippi, I; Lörstad, B; Loken, J G; López, J M; Loukas, D; Lutz, P; Lyons, L; MacNaughton, J N; Maehlum, G; Maio, A; Malychev, V; Mandl, F; Marco, J; Marco, R P; Maréchal, B; Margoni, M; Marin, J C; Mariotti, C; Markou, A; Maron, T; Martínez-Rivero, C; Martínez-Vidal, F; Martí i García, S; Masik, J; Matorras, F; Matteuzzi, C; Matthiae, Giorgio; Mazzucato, M; McCubbin, M L; McKay, R; McNulty, R; Medbo, J; Merk, M; Meroni, C; Meyer, S; Meyer, W T; Michelotto, M; Migliore, E; Mirabito, L; Mitaroff, Winfried A; Mjörnmark, U; Moa, T; Møller, R; Mönig, K; Monge, M R; Morettini, P; Müller, H; Mundim, L M; Murray, W J; Muryn, B; Myatt, Gerald; Naraghi, F; Navarria, Francesco Luigi; Navas, S; Nawrocki, K; Negri, P; Neumann, W; Neumeister, N; Nicolaidou, R; Nielsen, B S; Nieuwenhuizen, M; Nikolaenko, V; Niss, P; Nomerotski, A; Normand, Ainsley; Oberschulte-Beckmann, W; Obraztsov, V F; Olshevskii, A G; Onofre, A; Orava, Risto; Österberg, K; Ouraou, A; Paganini, P; Paganoni, M; Pagès, P; Palka, H; Papadopoulou, T D; Papageorgiou, K; Pape, L; Parkes, C; Parodi, F; Passeri, A; Pegoraro, M; Peralta, L; Pernegger, H; Pernicka, Manfred; Perrotta, A; Petridou, C; Petrolini, A; Petrovykh, M; Phillips, H T; Piana, G; Pierre, F; Pimenta, M; Pindo, M; Plaszczynski, S; Podobrin, O; Pol, M E; Polok, G; Poropat, P; Pozdnyakov, V; Prest, M; Privitera, P; Pukhaeva, N; Pullia, Antonio; Radojicic, D; Ragazzi, S; Rahmani, H; Rames, J; Ratoff, P N; Read, A L; Reale, M; Rebecchi, P; Redaelli, N G; Reid, D; Renton, P B; Resvanis, L K; Richard, F; Richardson, J; Rídky, J; Rinaudo, G; Ripp, I; Romero, A; Roncagliolo, I; Ronchese, P; Roos, L; Rosenberg, E I; Rosso, E; Roudeau, Patrick; Rovelli, T; Rückstuhl, W; Ruhlmann-Kleider, V; Ruiz, A; Rybicki, K; Saarikko, H; Sacquin, Yu; Sadovskii, A; Sajot, G; Salt, J; Sánchez, J; Sannino, M; Schimmelpfennig, M; Schneider, H; Schwickerath, U; Schyns, M A E; Sciolla, G; Scuri, F; Seager, P; Sedykh, Yu; Segar, A M; Seitz, A; Sekulin, R L; Shellard, R C; Siccama, I; Siegrist, P; Simonetti, S; Simonetto, F; Sissakian, A N; Sitár, B; Skaali, T B; Smadja, G; Smirnov, N; Smirnova, O G; Smith, G R; Solovyanov, O; Sosnowski, R; Souza-Santos, D; Spassoff, Tz; Spiriti, E; Sponholz, P; Squarcia, S; Stanescu, C; Stapnes, Steinar; Stavitski, I; Stichelbaut, F; Stocchi, A; Strauss, J; Strub, R; Stugu, B; Szczekowski, M; Szeptycka, M; Tabarelli de Fatis, T; Tavernet, J P; Chikilev, O G; Tilquin, A; Timmermans, J; Tkatchev, L G; Todorov, T; Toet, D Z; Tomaradze, A G; Tomé, B; Tonazzo, A; Tortora, L; Tranströmer, G; Treille, D; Trischuk, W; Tristram, G; Trombini, A; Troncon, C; Tsirou, A L; Turluer, M L; Tyapkin, I A; Tyndel, M; Tzamarias, S; Überschär, B; Ullaland, O; Uvarov, V; Valenti, G; Vallazza, E; Van der Velde, C; van Apeldoorn, G W; van Dam, P; Van Doninck, W K; Van Eldik, J; Vassilopoulos, N; Vegni, G; Ventura, L; Venus, W A; Verbeure, F; Verlato, M; Vertogradov, L S; Vilanova, D; Vincent, P; Vitale, L; Vlasov, E; Vodopyanov, A S; Vrba, V; Wahlen, H; Walck, C; Waldner, F; Weierstall, M; Weilhammer, Peter; Weiser, C; Wetherell, Alan M; Wicke, D; Wickens, J H; Wielers, M; Wilkinson, G R; Williams, W S C; Winter, M; Woschnagg, K; Yip, K; Yushchenko, O P; Zach, F; Zaitsev, A; Zalewska-Bak, A; Zalewski, Piotr; Zavrtanik, D; Zevgolatakos, E; Zimin, N I; Zito, M; Zontar, D; Zuberi, R; Zucchelli, G C; Zumerle, G

    1996-01-01

    Reconstructed \\lam\\ baryon decays and photon conversions in DELPHI are used to measure the \\sig\\ production rate from hadronic Z^0 decays at LEP. The number of \\sig\\ decays per hadronic Z decay is found to be: \\begin{center} = \\wffe{0.070}{0.010}{0.010 }{}. \\end{center} \\bigskip The \\Omega^- production rate is similarly measured to be: \\begin{center} = \\wffe{0.0014}{0.0002}{0.0004}{} \\end{center} by a combination of methods using constrained fits to the whole decay chain and particle identification.

  18. Decays of the vector glueball

    Science.gov (United States)

    Giacosa, Francesco; Sammet, Julia; Janowski, Stanislaus

    2017-06-01

    We calculate two- and three-body decays of the (lightest) vector glueball into (pseudo)scalar, (axial-)vector, as well as pseudovector and excited vector mesons in the framework of a model of QCD. While absolute values of widths cannot be predicted because the corresponding coupling constants are unknown, some interesting branching ratios can be evaluated by setting the mass of the yet hypothetical vector glueball to 3.8 GeV as predicted by quenched lattice QCD. We find that the decay mode ω π π should be one of the largest (both through the decay chain O →b1π →ω π π and through the direct coupling O →ω π π ). Similarly, the (direct and indirect) decay into π K K*(892 ) is sizable. Moreover, the decays into ρ π and K*(892 )K are, although subleading, possible and could play a role in explaining the ρ π puzzle of the charmonium state ψ (2 S ) thanks to a (small) mixing with the vector glueball. The vector glueball can be directly formed at the ongoing BESIII experiment as well as at the future PANDA experiment at the FAIR facility. If the width is sufficiently small (≲100 MeV ) it should not escape future detection. It should be stressed that the employed model is based on some inputs and simplifying assumptions: the value of glueball mass (at present, the quenched lattice value is used), the lack of mixing of the glueball with other quarkonium states, and the use of few interaction terms. It then represents a first step toward the identification of the main decay channels of the vector glueball, but shall be improved when corresponding experimental candidates and/or new lattice results will be available.

  19. Baryonic B decays

    Energy Technology Data Exchange (ETDEWEB)

    Kichimi, H. [High Energy Accelerator Research Organization, Tsukuba, Ibaraki (Japan). Institute of Particle and Nuclear Studies

    2005-07-01

    We present recent results of Baryonic B decays from Belle, which contain charmed and charmless baryonic decays into two to four body final states. We report the branching fractions, including new observations of the baryonic decays into two charmed baryons in the final states, and the charmless baryonic decay proceeding through b {yields} s{gamma} transition, and the low di-baryon mass enhancement structures observed in the three-body decays, based on 357 fb{sup -1} data. (author)

  20. Common missense mutation G1528C in long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency. Characterization and expression of the mutant protein, mutation analysis on genomic DNA and chromosomal localization of the mitochondrial trifunctional protein alpha subunit gene

    NARCIS (Netherlands)

    IJlst, L.; Ruiter, J. P.; Hoovers, J. M.; Jakobs, M. E.; Wanders, R. J.

    1996-01-01

    Mitochondrial trifunctional protein (MTP) is a recently identified enzyme involved in mitochondrial beta-oxidation, harboring long-chain enoyl-CoA hydratase, long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) and long-chain 3-ketothiolase activity. A deficiency of this protein is associated with

  1. Application of PERALS™ alpha spectrometry and gamma spectrometry for analysis and investigation of environmental spills at ISL uranium mining projects.

    Science.gov (United States)

    Borysenko, A; Ostrowski, A; Bellifemine, D; Palmer, G; Haigh, P; Johnston, A

    2014-03-01

    Radiation protection and environmental monitoring in mining requires effective and reliable radionuclide analysis at all stages of the mine project-prior to mining, during operation and through to remediation and decommissioning. The approach presented in this paper was specially developed for the monitoring of radioactive waste resulting from spills during mining and mineral processing operations and uses a combination of high resolution gamma spectrometry, and PERALS™ alpha spectrometry to identify and reliably quantify the activity of the major members of the U-238 decay chain at activities down to 10 mBq g(-1) by direct radionuclide counting and by assessment of the activity of their decay products. This approach has reduced sample preparation and analysis time while providing effective analysis and quantification of naturally occurring radionuclides in environmental samples. It has been successfully applied to several in situ leach (ISL) mining-related projects involving investigations of process material spill impacts and also to routine environmental monitoring.

  2. Radioactive decay of sup(91m)Nb

    Energy Technology Data Exchange (ETDEWEB)

    Lakshminarayana, V.; Venkataratnam, S.; Rao, B.V.T.; Narasimham, K.L.; Chintalapudi, S.N.

    1987-08-01

    The radioactive decay of sup(91m)Nb, produced by the reaction /sup 89/Y(..cap alpha.., 2n), is studied using Ge(Li), HPGe and Si(Li) detectors. The K-conversion coefficient, ..cap alpha..sub(K), of the 104.5 keV transition is determined accurately, for the first time, from the Nb Ksub(..cap alpha..) x-ray and 104.5 keV gamma-ray intensities. The experimental value of ..cap alpha..sub(K) thus determined is 115(5), in agreement with the value expected for an M4 transition.

  3. Persistence of Anderson localization in Schrodinger operators with decaying random potentials

    CERN Document Server

    Figotin, A; Klein, A; Müller, P

    2006-01-01

    We show persistence of both Anderson and dynamical localization in Schrodinger operators with non-positive (attractive) random decaying potential. We consider an Anderson-type Schr\\"odinger operator with a non-positive ergodic random potential, and multiply the random potential by a decaying envelope function. If the envelope function decays slower than $|x|^{-2}$ at infinity, we prove that the operator has infinitely many eigenvalues below zero. For envelopes decaying as $|x|^{-\\alpha}$ at infinity, we determine the number of bound states below a given energy $E<0$, asymptotically as $\\alpha\\downarrow 0$. To show that bound states located at the bottom of the spectrum are related to the phenomenon of Anderson localization in the corresponding ergodic model, we prove: ~(a)~ these states are exponentially localized with a localization length that is uniform in the decay exponent $\\alpha$; (b)~ dynamical localization holds uniformly in $\\alpha$.

  4. Chain Posets

    OpenAIRE

    Johnson, Ian T.

    2018-01-01

    A chain poset, by definition, consists of chains of ordered elements in a poset. We study the chain posets associated to two posets: the Boolean algebra and the poset of isotropic flags. We prove that, in both cases, the chain posets satisfy the strong Sperner property and are rank-log concave.

  5. Recent results on hadronic D/sub s/ and D meson decays from the Mark III

    Energy Technology Data Exchange (ETDEWEB)

    Adler, J.; Bai, Z.; Blaylock, G.T.; Bolton, T.; Brient, J.C.; Browder, T.E.; Brown, J.S.; Bunnell, K.O.; Burchell, M.; Burnett, T.H.; Cassell, R.E.; Coffman, D.; Cook, V.; Coward, D.H.

    1989-07-01

    Recent results on hadronic D/sub s/ and D decays from the Mark III collaboration are presented. The absolute branching ratio B(D/sub s//sup +/ /yields/ /phi//pi//sup +/) is studied by searching for fully reconstructed e/sup +/e/sup /minus// /yields/ D/sub s/*/sup /plus minus//D/sub s//sup /minus plus// events using seven hadronic decay modes of the D/sub s//sup +/. A limit of B(D/sub s//sup +/ /yields/ /phi//pi//sup +/) < 4.1% at 90% C.L. is obtained. Evidence is presented for the decay D/sub s//sup +/ /yields/ f/sub 0/(975)/pi//sup +/ which agrees with a recent experimental observation. Upper limits are set for the relative branching ratios B(D/sub s//sup +/ /yields/ /eta//pi//sup +/)/B(D/sub s//sup +/ /yields/ /phi//pi//sup +/) < 2.5 and B(D/sub s//sup +/ /yields/ /eta//prime//pi//sup +/)/B(D/sub s//sup +/ /yields/ /phi//pi//sup +/) < 1.9, where the /eta/ is studied in both the /gamma//gamma/ and the /pi//sup +//pi//sup /minus///pi//sup 0/ decay modes and the /eta//prime/ in the /eta//pi//sup +//pi//sup /minus//, /eta/ /yields/ /gamma//gamma/ decay chain. The resonant substructure of D/sup 0/ /yields/ K/sup /minus///pi//sup +//pi//sup /minus///pi//sup +/ and D/sup +/ /yields/ /bar K//sup 0//pi//sup +//pi//sup /minus///pi//sup +/ is studied. The branching ratio of D/sup 0/ /yields/ /bar K/*/sup 0//rho//sup 0/ is found to be smaller than the theoretically expected whereas the decay modes D/sup 0/ /yields/ /alpha//sub 1//sup +/K/sup /minus// and D/sup +/ /yields/ /alpha//sub 1//sup +//bar K//sup 0/ are found to be large and account for 50% of these final states. 33 refs., 9 figs., 2 tabs.

  6. MODEL RADIOACTIVE RADON DECAY

    Directory of Open Access Journals (Sweden)

    R.I. Parovik

    2012-06-01

    Full Text Available In a model of radioactive decay of radon in the sample (222Rn. The model assumes that the probability of the decay of radon and its half-life depends on the fractal properties of the geological environment. The dependencies of the decay parameters of the fractal dimension of the medium.

  7. B decays to excited charm mesons

    Energy Technology Data Exchange (ETDEWEB)

    Colangelo, P.; De Fazio, F.; Paver, N

    1999-04-01

    We review several aspects of the phenomenology of P-wave q-barQ mesons: mass splittings, effective strong couplings and leptonic constants. We also describe a QCD sum rule determination to order {alpha}{sub s} of the form factor {tau}{sub 1/}2(y) governing the semileptonic B decays to the charm doublet with J{sup P} = (0{sup +}{sub 1/2}), 1{sup +}{sub 1/2}))00.

  8. Residual-interaction renormalization effect on the spherical-nuclei α-decay absolute widths

    International Nuclear Information System (INIS)

    Dumitresku, T.; Kadmenskij, S.G.; Lomachenkov, I.A.; Kholan, S.; Furman, V.I.

    1978-01-01

    In the framework of the shell model approximation for the probabilities of alpha-decay the exact formulas (for alpha-widths) taking into account the contribution of density dependent effective interaction between nucleons forming the emitted alpha-particle are obtained. In agreement with previous estimations the numerical calculation reveals that the inclusion of the above-mentioned interaction is followed by some decrease of absolute alpha-widths

  9. Regulation by retinoids of luteinizing hormone/chorionic gonadotropin receptor, cholesterol side-chain cleavage cytochrome P-450, 3 beta-hydroxysteroid dehydrogenase/delta (5-4)-isomerase and 17 alpha-hydroxylase/C17-20 lyase cytochrome P-450 messenger ribonucleic acid levels in the K9 mouse Leydig cell line.

    Science.gov (United States)

    Lefèvre, A; Rogier, E; Astraudo, C; Duquenne, C; Finaz, C

    1994-12-01

    Vitamin A is a potent regulator of testicular function. We have reported that retinol (R) and retinoic acid (RA) induced a down regulation of luteinizing hormone/human chorionic gonadotropin (LH/CG) binding sites in K9 Leydig cells. In the present study we evaluated the effect of R and RA on LH/CG receptors, cholesterol side-chain cleavage cytochrome P-450 (P-450 scc), 17 alpha-hydroxylase/C17-20 lyase (P-450 17 alpha) and 3 beta-hydroxysteroid dehydrogenase (3 beta HSD) mRNA levels in K9 mouse Leydig cells. To validate K9 cells as a model for studying Leydig cell steroidogenesis at the molecular level, we first investigated the effect of hCG on mRNA levels of the steroidogenic enzymes. P-450 scc, 3 beta HSD and P-450 17 alpha were expressed constitutively. The addition of 10 ng/ml hCG enhanced mRNA levels for the three genes within 2 h. Maximal accumulation of P-450 scc, P-450 17 alpha and 3 beta HSD mRNA in treated cells represents a 2.5-, 8.5- and 4-fold increase over control values, respectively. P-450 17 alpha expression reached a maximum by 4 h and then declined rapidly to return to control value by 24 h. The pattern of LH/CG receptor mRNAs in K9 cells was very similar to that of MA10 Leydig cells and showed six transcripts of 1.1, 1.6, 1.9, 2.6, 4.2 and 7.0 kb. Treatment of cells with R or RA resulted in a time- and dose-dependent decrease in all six species.(ABSTRACT TRUNCATED AT 250 WORDS)

  10. Increased frequency of CD4{sup -}8{sup -}T cells bearing T-cell receptor {alpha}{beta} chains in peripheral blood of atomic bomb survivors exposed to high doses

    Energy Technology Data Exchange (ETDEWEB)

    Yoichiro Kusunoki; Seishi Kyoizumi; Yuko Hirai; Shoichiro Fujita; Mitoshi Akiyama [Radiation Effects Research Foundation, Hiroshima (Japan)

    1994-07-01

    A rare T-cell subpopulation, CD4{sup -z}8{sup -}{alpha}{beta} cells, may be differentiated through a pathway (or pathways) different from the pathway(s) of conventional CD4+ or CD8+ cells. In the present study, the frequencies of CD4{sup -}8{sup -} T cells in peripheral-blood {alpha}{beta} T cells in 409 atomic bomb survivors were determined to investigate late effects of radiation on the composition of human T-cell subpopulations. The frequency of CD4{sup -}8{sup -}{alpha}{beta} T-cell decreased significantly with the subject`s age and was higher in females than males. A significant increase in the frequency was found in the survivors exposed to more than 1.5Gy, suggesting that the previous radiation exposure altered differentiation and development of T cells. 25 refs., 4 figs., 3 tabs.

  11. Genetic and biosynthetic studies of families carrying hemoglobin J alpha Mexico: association of alpha-thalassemia with HbJ.

    Science.gov (United States)

    Trabuchet, G; Benabadji, M; Labie, D

    1978-06-09

    Hemoglobin J Mexico, an alpha chain mutant, was studied in eight unrelated Algerian families. The quantities of the abnormal hemoglobin in 116 subjects are trimodally distributed: 55% in homozygotes, 31% and 38% in heterozygotes. Both hematological data and the alpha/beta chain biosynthetic ratio are normal in heterozygotes with 31% Hb J and in homozygotes. In contrast, the MCV and MCH as well as the alpha/beta biosynthetic ratio are slightly reduced in heterozygotes with 38% Hb J and in their relatives carrying Hb A. The elevated expression of alphaJ chains in heterozygotes with 38% Hb J may be due to an alpha thalassemia gene trans to the alphaJ locus.

  12. ENDOPLASMIC RETICULUM-MEDIATED QUALITY-CONTROL OF TYPE-I COLLAGEN PRODUCTION BY CELLS FROM OSTEOGENESIS IMPERFECTA PATIENTS WITH MUTATIONS IN THE PRO-ALPHA-1(I) CHAIN CARBOXYL-TERMINAL PROPEPTIDE WHICH IMPAIR SUBUNIT ASSEMBLY

    NARCIS (Netherlands)

    LAMANDE, [No Value; CHESSLER, SD; GOLUB, SB; BYERS, PH; CHAN, D; COLE, WG; SILLENCE, DO; BATEMAN, JF

    1995-01-01

    A heterozygous single base change in exon 49 of COL1A1, which converted the codon for pro alpha 1(I) carboxyl-terminal propeptide residue 94 from tryptophan (TGG) to cysteine (TGT) was identified in a baby with lethal osteogenesis imperfecta (OI64). The C-propeptide mutations in OI64 and in another

  13. Rare Decays at LHCb

    Science.gov (United States)

    Hall, Sam

    2014-04-01

    Rare decays of beauty and charm hadrons provide an effective method of testing the Standard Model and probing possible new physics scenarios. The LHCb experiment has published a variety of interesting results in this field, some of which are presented here. In particular the measurements of the branching fractions of B(s)0 → μ+μ- which, in combination with CMS, resulted in the first observation of the Bs0 → μ+μ- decay. Other topics include searches for the rare decay D0 → μ+μ-, the lepton flavour violating decays B(s)0 → e±μ∓, and the observation of the ψ(4160) resonance in the region of low recoil in B+ → K+μ+μ- decay. New results on the angular analysis of the decay B0 → K*0μ+μ- with form factor independent observables are also shown.

  14. Status of μ decays

    International Nuclear Information System (INIS)

    Kinnison, W.W.

    1983-01-01

    A short theoretical review of the weak interaction is presented with particular emphasis on the implications to normal and rare muon decay processes. This review addresses the standard theory, left-right symmetry theories, theories with horizontal symmetries, and composite models. A survey of experiments currently in progress to study both rare and normal muon decays is then presented with particular emphasis on the Los Alamos high statistics muon decay experiment and its implications for left-right symmetric theories. 16 references

  15. Neutrinoless double beta decay

    Indian Academy of Sciences (India)

    2012-10-06

    Oct 6, 2012 ... nuclear decay of neutrinoless double beta decay typically leading to sub-eV values as well. (Z, A) → (Z + 2, A) + 2e .... Here again energy resolution matters, because of the continuous spectrum of the 2νββ- decay mode, its high .... The benefit of using Te is its high natural abundance. This experiment is in ...

  16. Effective Majorana neutrino decay

    Energy Technology Data Exchange (ETDEWEB)

    Duarte, Lucia [Instituto de Fisica, Facultad de Ingenieria,Universidad de la Republica, Montevideo (Uruguay); Romero, Ismael; Peressutti, Javier; Sampayo, Oscar A. [Universidad Nacional de Mar del Plata, Departamento de Fisica, Instituto de Investigaciones Fisicas de Mar del Plata (IFIMAR) CONICET, UNMDP, Mar del Plata (Argentina)

    2016-08-15

    We study the decay of heavy sterile Majorana neutrinos according to the interactions obtained from an effective general theory. We describe the two- and three-body decays for a wide range of neutrino masses. The results obtained and presented in this work could be useful for the study of the production and detection of these particles in a variety of high energy physics experiments and astrophysical observations. We show in different figures the dominant branching ratios and the total decay width. (orig.)

  17. Axigluon decays of toponium

    International Nuclear Information System (INIS)

    Faustov, R.N.; Vasilevskaya, I.G.

    1990-01-01

    Chiral-colour model predicts the existence of axigluons which is an octet of massive axial-vector gauge bosons. In this respect toponium decays into axigluons and gluons are of interest. The following toponium decays are considered: θ → Ag, θ → AAg, θ → ggg → AAg. The width of toponium S-state decays is calculated under various possible values of axigluon mass

  18. Sequences related to HLA-DRα chain on human chromosome 6: Restriction enzyme polymorphism detected with DCα chain probes.

    NARCIS (Netherlands)

    J. Trowsdale (John); J.S. Lee (Janet); J.E. Carey (Janet); F.G. Grosveld (Frank); J.G. Bodmer (Julia); W.F. Bodmer (Walter)

    1983-01-01

    markdownabstractThree sets of cosmid clones--containing the HLA-DR alpha chain gene and two additional related genes--were isolated from human genomic DNA libraries by using a cDNA probe for the HLA-DR alpha chain. Southern blot analysis using DNA from somatic cell hybrids indicated that all of the

  19. Rare Kaon Decays

    International Nuclear Information System (INIS)

    Kudenko, Y.

    1999-01-01

    The past few years have seen an evolution in the study of rare K decays from a concentration on explicitly Standard Model (SM) violating decays such as K L 0 → μe, to one on SM-allowed but suppressed decays such as K → πν| ν, in which short-distance interactions are dominant. There are also a number of recent experimental and theoretical studies of long-distance-dominated decays, but they do not have space to cover these, with the exception of those that are needed in the discussion of the short-distance-dominated processes

  20. Deviations from exponential decay

    Science.gov (United States)

    Petridis, Athanasios; Staunton, Lawrence; Luban, Marshall; Vermedahl, Jon

    2003-10-01

    We study deviations from exponetial decay in cases when the initial wavefunction is set in a potential well and is not an eigenstate of this potential. We numerically solve the time-dependent Schroedinger equation and observe a decaying but oscillatory behavior of the survival probability. Analytical calculations have been performed proving that even in the case of a simple finite square-well potential deviations from exponential decay persist for large times. Possible explanations for the limiting exponential decay for many-particle systems are developed.

  1. Coulomb correction to elastic. alpha. -. alpha. scattering

    Energy Technology Data Exchange (ETDEWEB)

    Bera, P.K.; Jana, A.K.; Haque, N.; Talukdar, B. (Department of Physics, Visva-Bharati University, Santiniketan-731235, West Bengal, India (IN))

    1991-02-01

    The elastic {alpha}-{alpha} scattering is treated within the framework of a generalized phase-function method (GPFM). This generalization consists in absorbing the effect of Coulomb interaction in the comparison functions for developing the phase equation. Based on values of scattering phase shifts computed by the present method, it is concluded that the GPFM provides an uncomplicated approach to rigorous Coulomb correction in the {alpha}-{alpha} scattering.

  2. Sterically hindered C(alpha, alpha)-disubstituted alpha-amino acids: synthesis from alpha-nitroacetate and incorporation into peptides.

    Science.gov (United States)

    Fu, Y; Hammarström, L G; Miller, T J; Fronczek, F R; McLaughlin, M L; Hammer, R P

    2001-10-19

    The preparation of sterically hindered and polyfunctional C(alpha,alpha)-disubstituted alpha-amino acids (alpha alpha AAs) via alkylation of ethyl nitroacetate and transformation into derivatives ready for incorporation into peptides are described. Treatment of ethyl nitroacetate with N,N-diisopropylethylamine (DIEA) in the presence of a catalytic amount of tetraalkylammonium salt, followed by the addition of an activated alkyl halide or Michael acceptor, gives the doubly C-alkylated product in good to excellent yields. Selective nitro reduction with Zn in acetic acid or hydrogen over Raney Ni gives the corresponding amino ester that, upon saponification, can be protected with the fluorenylmethyloxycarbonyl (Fmoc) group. The first synthesis of an orthogonally protected, tetrafunctional C(alpha,alpha)-disubstituted analogue of aspartic acid, 2,2-bis(tert-butylcarboxymethyl)glycine (Bcmg), is described. Also, the sterically demanding C(alpha,alpha)-dibenzylglycine (Dbg) has been incorporated into a peptide using solid-phase synthesis. It was found that once sterically congested Dbg is at the peptide N-terminus, further chain extension becomes very difficult using uronium or phosphonium salts (PyAOP, PyAOP/HOAt, HATU). However, preformed amino acid symmetrical anhydride couples to N-terminal Dbg in almost quantitative yield in nonpolar solvent (dichloroethane-DMF, 9:1).

  3. Alpha-cluster preformation factor within cluster-formation model for odd-A and odd-odd heavy nuclei

    Science.gov (United States)

    Saleh Ahmed, Saad M.

    2017-06-01

    The alpha-cluster probability that represents the preformation of alpha particle in alpha-decay nuclei was determined for high-intensity alpha-decay mode odd-A and odd-odd heavy nuclei, 82 CSR) and the hypothesised cluster-formation model (CFM) as in our previous work. Our previous successful determination of phenomenological values of alpha-cluster preformation factors for even-even nuclei motivated us to expand the work to cover other types of nuclei. The formation energy of interior alpha cluster needed to be derived for the different nuclear systems with considering the unpaired-nucleon effect. The results showed the phenomenological value of alpha preformation probability and reflected the unpaired nucleon effect and the magic and sub-magic effects in nuclei. These results and their analyses presented are very useful for future work concerning the calculation of the alpha decay constants and the progress of its theory.

  4. β decay studies of n-rich Cs isotopes with the ISOLDE Decay Station

    Science.gov (United States)

    Lică, R.; Benzoni, G.; Morales, A. I.; Borge, M. J. G.; Fraile, L. M.; Mach, H.; Madurga, M.; Sotty, C.; Vedia, V.; De Witte, H.; Benito, J.; Berry, T.; Blasi, N.; Bracco, A.; Camera, F.; Ceruti, S.; Charviakova, V.; Cieplicka-Oryńczak, N.; Costache, C.; Crespi, F. C. L.; Creswell, J.; Fernández-Martínez, G.; Fynbo, H.; Greenlees, P.; Homm, I.; Huyse, M.; Jolie, J.; Karayonchev, V.; Köster, U.; Konki, J.; Kröll, T.; Kurcewicz, J.; Kurtukian-Nieto, T.; Lazarus, I.; Leoni, S.; Lund, M.; Marginean, N.; Marginean, R.; Mihai, C.; Mihai, R.; Negret, A.; Orduz, A.; Patyk, Z.; Pascu, S.; Pucknell, V.; Rahkila, P.; Regis, J. M.; Rotaru, F.; Saed-Sami, N.; Sánchez-Tembleque, V.; Stanoiu, M.; Tengblad, O.; Thuerauf, M.; Turturica, A.; Van Duppen, P.; Warr, N.

    2017-05-01

    Neutron-rich Ba isotopes are expected to exhibit octupolar correlations, reaching their maximum in isotopes around mass A = 146. The odd-A neutron-rich members of this isotopic chain show typical patterns related to non-axially symmetric shapes, which are however less marked compared to even-A ones, pointing to a major contribution from vibrations. In the present paper we present results from a recent study focused on 148-150Cs β-decay performed at the ISOLDE Decay Station equipped with fast-timing detectors. A detailed analysis of the measured decay half-lives and decay scheme of 149Ba is presented, giving a first insight in the structure of this neutron-rich nucleus.

  5. Intrahepatic expression of interferon alpha & interferon alpha ...

    African Journals Online (AJOL)

    kemrilib

    Alpha m-RNA while 30% only expressed Interferon Alpha Receptor m-RNA. Responders and non-responders to Interferon therapy ... expression of IFN Alpha Receptor mRNA. Regardless of the response to interferon, histological .... generation reverse hybridisation, line probe assay. (Inno-LiPA HCV II; Innogenetics, Ghent,.

  6. Monoclonal antibody based immunoassays to screen for alpha-thalassemia in adults

    Energy Technology Data Exchange (ETDEWEB)

    Epstein, N.; Than, K.A. Culp, K.M. [Isolab, Inc., Akron, OH (United States)] [and others

    1994-09-01

    Alpha-thalassemia (alpha-thal) is characterized by the absence or reduction in synthesis of the alpha-globin chain due to either deletions or other abnormalities involving the alpha-globin genes located on the short arm of chromosome 16. The diploid cells have four alpha chain genes. The deletion of one, two, three or all four of these genes could result in mild to a complete alpha chain deficiency known as the Hydrops fetalis syndrome or alpha-thal-1, which causes fetal death. It is important to develop a sensitive test to detect carriers of alpha-thal-1 trait for genetic counseling. It has recently been observed that the presence of minute amounts of zeta-globin chains (0.01-1%) could serve as a biological marker of alpha-thal carriers. Because high sensitivity is required, we constructed a monoclonal antibody-based immunoassay which can be analyzed either by colorimetric or fluorimetric methods. By testing blood samples from individuals of Southeast Asian ancestry, we were able to show that various forms and combinations of deletions or inactivations of two or three alpha-globin genes results in alpha-thalassemia conditions that have elevated levels of the zeta-chain. Sensitivity achieved in these tests was < 0.1% zeta chain, or as low as 5 ng zeta-chain. Data correlate with results from reversed phase HPLC.

  7. Decay properties of {sup 256-339}Ds superheavy nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Santhosh, K.P.; Nithya, C. [Kannur University, School of Pure and Applied Physics, Payyanur, Kerala (India)

    2017-09-15

    The decay properties of 84 isotopes of darmstadtium superheavy nuclei (Z = 110) have been studied using various theoretical models. The proton emission half-lives, the alpha decay half-lives, the spontaneous fission half-lives and the cluster decay half-lives of all the isotopes are evaluated. The one-proton emission half-lives and the alpha decay half-lives are predicted using the Coulomb and proximity potential model for deformed nuclei (CPPMDN). The calculated alpha half-lives are compared with the available experimental results as well as with the predictions of other theoretical models. The predicted half-lives matches well with the experimental results. The one-proton half-lives are also compared with the predictions using other formalisms. The shell-effect-dependent formula of Santhosh et al. has been employed for calculating the spontaneous fission half-lives. A theoretical comparison of spontaneous fission half-lives with four different formalisms is performed. By comparing the one-proton emission half-lives, the alpha decay half-lives and the spontaneous fission half-lives decay modes are predicted for all the isotopes of Ds. It is seen that the isotopes within the range 256 ≤ A ≤ 263 and 279 ≤ A ≤ 339 decay through spontaneous fission and the isotopes 264 ≤ A ≤ 278 exhibit alpha decay. Cluster decay half-lives are calculated using different models including the Coulomb and proximity potential (CPPM), for determining the magicities in the superheavy region. The effect of magicity at N = 184 and N = 202 were confirmed from the plot of log{sub 10}T{sub 1/2} versus neutron number of the daughter nuclei for the emission of different clusters. We hope that the systematic and detailed study of all the possible decay modes of {sup 256-339}Ds using various theoretical models will be helpful in the experimental identification of the isotopes of the element in the future. (orig.)

  8. DOS cones along atomic chains

    International Nuclear Information System (INIS)

    Kwapiński, Tomasz

    2017-01-01

    The electron transport properties of a linear atomic chain are studied theoretically within the tight-binding Hamiltonian and the Green’s function method. Variations of the local density of states (DOS) along the chain are investigated. They are crucial in scanning tunnelling experiments and give important insight into the electron transport mechanism and charge distribution inside chains. It is found that depending on the chain parity the local DOS at the Fermi level can form cone-like structures (DOS cones) along the chain. The general condition for the local DOS oscillations is obtained and the linear behaviour of the local density function is confirmed analytically. DOS cones are characterized by a linear decay towards the chain which is in contrast to the propagation properties of charge density waves, end states and Friedel oscillations in one-dimensional systems. We find that DOS cones can appear due to non-resonant electron transport, the spin–orbit scattering or for chains fabricated on a substrate with localized electrons. It is also shown that for imperfect chains (e.g. with a reduced coupling strength between two neighboring sites) a diamond-like structure of the local DOS along the chain appears. (paper)

  9. Rare decays at LHCb

    CERN Document Server

    Adrover Pacheco, Cosme

    2012-01-01

    Rare decays are excellent tests to infer the presence of physics beyond the Standard Model (BSM), as they occur through processes prohibited at tree level in the SM. Any deviation from the SM prediction in branching fraction or angular distributions of such decays can lead to indications of new physics.

  10. Aspects of B decays

    International Nuclear Information System (INIS)

    Faller, Sven

    2011-01-01

    B-meson decays are a good probe for testing the flavour sector of the standard model of particle physics. The standard model describes at present all experimental data satisfactorily, although some ''tensions'' exist, i.e. two to three sigma deviations from the predictions, in particular in B decays. The arguments against the standard model are thus purely theoretical. These tensions between experimental data and theoretical predictions provide an extension of the standard model by new physics contributions. Within the flavour sector main theoretical uncertainties are related to the hadronic matrix elements. For exclusive semileptonic anti B → D (*) l anti ν decays QCD sum rule techniques, which are suitable for studying hadronic matrix elements, however, with substantial, but estimable hadronic uncertainties, are used. The exploration of new physics effects in B-meson decays is done in an twofold way. In exclusive semileptonic anti B → D (*) l anti ν decays the effect of additional right-handed vector as well as left- and right-handed scalar and tensor hadronic current structures in the decay rates and the form factors are studied at the non-recoil point. As a second approach one studied the non-leptonic B 0 s →J/ψφ and B 0 →J/ψK S,L decays discussing CP violating effects in the time-dependent decay amplitudes by considering new physics phase in the B 0 - anti B 0 mixing phase. (orig.)

  11. Induced nuclear beta decay

    International Nuclear Information System (INIS)

    Reiss, H.R.

    1986-01-01

    Certain nuclear beta decay transitions normally inhibited by angular momentum or parity considerations can be induced to occur by the application of an electromagnetic field. Such decays can be useful in the controlled production of power, and in fission waste disposal

  12. Multiple preequilibrium decay processes

    International Nuclear Information System (INIS)

    Blann, M.

    1987-11-01

    Several treatments of multiple preequilibrium decay are reviewed with emphasis on the exciton and hybrid models. We show the expected behavior of this decay mode as a function of incident nucleon energy. The algorithms used in the hybrid model treatment are reviewed, and comparisons are made between predictions of the hybrid model and a broad range of experimental results. 24 refs., 20 figs

  13. B decays to baryons

    Indian Academy of Sciences (India)

    We note that two-body decays to baryons are suppressed relative to three- and four-body decays. In most of these analyses, the invariant baryon–antibaryon mass shows an enhancement near the threshold. We propose a phenomenological interpretation of this quite common feature of hadronization to baryons.

  14. Chapter 3: Wood Decay

    Science.gov (United States)

    Dan Cullen

    2014-01-01

    A significant portion of global carbon is sequestered in forest systems. Specialized fungi have evolved to efficiently deconstruct woody plant cell walls. These important decay processes generate litter, soil bound humic substances, or carbon dioxide and water. This chapter reviews the enzymology and molecular genetics of wood decay fungi, most of which are members of...

  15. Cavities/Tooth Decay

    Science.gov (United States)

    ... a process that occurs over time. Here's how tooth decay develops: Plaque forms. Dental plaque is a clear sticky film that coats ... by a lack of saliva, which helps prevent tooth decay by washing away food and plaque from your teeth. Substances found in saliva also help counter the ...

  16. Decay of hypernuclei

    International Nuclear Information System (INIS)

    Bando, H.

    1985-01-01

    The pionic and non-mesonic decays of hypernuclei are discussed. In the first part, various decay processes which could be useful to obtain information of hypernuclear structure are discussed. The experimental data concerning the pionic and non-mesonic decays are discussed in the second part. As the experimental data, there are only few lifetime data and some crude data on the non-mesonic to π decay ratio. In the third and the fourth parts, some theoretical analyses are made on the pionic and the nonmesonic decays. DDHF calculation was performed for Λ and N systems by using Skyrme type ΛN and NN effective interactions. A suppression factor of the order of 10 -3 for A nearly equal 100 was obtained. (Aoki, K.)

  17. Branched-chain alpha-keto acid catabolism via the gene products of the bkd operon in Enterococcus faecalis: a ne, secreted metabolite serving as a temporary redox sink.

    NARCIS (Netherlands)

    Ward, D.E.; van der Weijden, C.C.; van der Merwe, M.J.; Westerhoff, H.V.; Claiborne, A.; Snoep, J.L.

    2000-01-01

    Recently the bkd gene cluster from Enterococcus faecalis was sequenced, and it was shown that the gene products constitute a pathway for the catabolism of branched-chain α-keto acids. We have now investigated the regulation and physiological role of this pathway. Primer extension analysis identified

  18. Decay of heavy and superheavy nuclei

    Indian Academy of Sciences (India)

    study on the feasibility of observing α decay chains from the isotopes of the superheavy nuclei. Z = 115 in the range 271 ≤ A ≤ 294 and the isotopes of Z = 117 in the range 270 ≤ A ≤ 301, within the Coulomb and .... For Ri we use semiempirical formula in terms of mass number Ai as [3]. Ri = 1.28A. 1/3 i. − 0.76 + 0.8A.

  19. Decay properties of high-lying single-particles modes

    NARCIS (Netherlands)

    Beaumel, D; Fortier, S; Gales, S; Guillot, J; LangevinJoliot, H; Laurent, H; Maison, JM; Vernotte, J; Bordewijck, J; Brandenburg, S; Krasznahorkay, A; Crawley, GM; Massolo, CP; Renteria, M; Khendriche, A

    1996-01-01

    The neutron decay of high-lying single-particle states in Ni-64, Zr-90, Sn-120 and (208)pb excited by means of the (alpha,He-3) reaction has been investigated at 120 MeV incident energy using the multidetector EDEN. The characteristics of this reaction are studied using inclusive spectra and angular

  20. Stromal laminin chain distribution in normal, hyperplastic and malignant oral mucosa: relation to myofibroblast occurrence and vessel formation.

    Science.gov (United States)

    Franz, Marcus; Wolheim, Anke; Richter, Petra; Umbreit, Claudia; Dahse, Regine; Driemel, Oliver; Hyckel, Peter; Virtanen, Ismo; Kosmehl, Hartwig; Berndt, Alexander

    2010-04-01

    The contribution of stromal laminin chain expression to malignant potential, tumour stroma reorganization and vessel formation in oral squamous cell carcinoma (OSCC) is not fully understood. Therefore, the expression of the laminin chains alpha2, alpha3, alpha4, alpha5 and gamma2 in the stromal compartment/vascular structures in OSCC was analysed. Frozen tissue of OSCC (9x G1, 24x G2, 8x G3) and normal (2x)/hyperplastic (11x) oral mucosa was subjected to laminin chain and alpha-smooth muscle actin (ASMA) immunohistochemistry. Results were correlated to tumour grade. The relation of laminin chain positive vessels to total vessel number was assessed by immunofluorescence double labelling with CD31. Stromal laminin alpha2 chain significantly decreases and alpha3, alpha4, alpha5 and gamma2 chains and also ASMA significantly increase with rising grade. The amount of stromal alpha3, alpha4 and gamma2 chains significantly increased with rising ASMA positivity. There is a significant decrease in alpha3 chain positive vessels with neoplastic transformation. Mediated by myofibroblasts, OSCC development is associated with a stromal up-regulation of laminin isoforms possibly contributing to a migration promoting microenvironment. A vascular basement membrane reorganization concerning alpha3 and gamma2 chain laminins during tumour angioneogenesis is suggested.

  1. Apparatus for detecting alpha radiation in difficult access areas

    International Nuclear Information System (INIS)

    Steadman, P.; MacArthur, D.W.

    1997-01-01

    An electrostatic alpha radiation detector for measuring alpha radiation emitted from inside an enclosure comprising an electrically conductive expandable electrode for insertion into the enclosure is disclosed. After insertion, the electrically conductive expandable electrode is insulated from the enclosure and defines a decay cavity between the electrically conductive expandable electrode and the enclosure so that air ions generated in the decay cavity are electrostatically captured by the electrically conductive expandable electrode and the enclosure when an electric potential is applied between the electrically conductive expandable electrode and the enclosure. Indicator means are attached to the electrically conductive expandable electrode for indicating an electrical current produced by generation of the air ions generated in the decay cavity by collisions between air molecules and the alpha particles emitted from the enclosure. A voltage source is connected between the indicator means and the electrically conductive enclosure for creating an electric field between the electrically conductive expandable electrode and the enclosure. 4 figs

  2. Proceedings, High-Precision $\\alpha_s$ Measurements from LHC to FCC-ee

    Energy Technology Data Exchange (ETDEWEB)

    d' Enterria, David [CERN; Skands, Peter Z. [Monash U.

    2015-01-01

    This document provides a writeup of all contributions to the workshop on "High precision measurements of $\\alpha_s$: From LHC to FCC-ee" held at CERN, Oct. 12--13, 2015. The workshop explored in depth the latest developments on the determination of the QCD coupling $\\alpha_s$ from 15 methods where high precision measurements are (or will be) available. Those include low-energy observables: (i) lattice QCD, (ii) pion decay factor, (iii) quarkonia and (iv) $\\tau$ decays, (v) soft parton-to-hadron fragmentation functions, as well as high-energy observables: (vi) global fits of parton distribution functions, (vii) hard parton-to-hadron fragmentation functions, (viii) jets in $e^\\pm$p DIS and $\\gamma$-p photoproduction, (ix) photon structure function in $\\gamma$-$\\gamma$, (x) event shapes and (xi) jet cross sections in $e^+e^-$ collisions, (xii) W boson and (xiii) Z boson decays, and (xiv) jets and (xv) top-quark cross sections in proton-(anti)proton collisions. The current status of the theoretical and experimental uncertainties associated to each extraction method, the improvements expected from LHC data in the coming years, and future perspectives achievable in $e^+e^-$ collisions at the Future Circular Collider (FCC-ee) with $\\cal{O}$(1--100 ab$^{-1}$) integrated luminosities yielding 10$^{12}$ Z bosons and jets, and 10$^{8}$ W bosons and $\\tau$ leptons, are thoroughly reviewed. The current uncertainty of the (preliminary) 2015 strong coupling world-average value, $\\alpha_s(m_Z)$ = 0.1177 $\\pm$ 0.0013, is about 1\\%. Some participants believed this may be reduced by a factor of three in the near future by including novel high-precision observables, although this opinion was not universally shared. At the FCC-ee facility, a factor of ten reduction in the $\\alpha_s$ uncertainty should be possible, mostly thanks to the huge Z and W data samples available.

  3. Comparison of transcript levels and mRNA half-lives for the subunits of the branched-chain {alpha}-keto acid dehydrogenase (BCKD) complex in two human cell lines

    Energy Technology Data Exchange (ETDEWEB)

    Bowers, B.A.; Danner, D.J. [Emory Univ., Atlanta, GA (United States)

    1994-09-01

    BCKD is a mitochondrial multienzyme complex that catalyzes the committed step in catabolism of the keto acid derivatives of leucine, isoleucine and valine. Three subunits, El{alpha}, E1{beta} and E2 are specific to the complex. The subunits are nuclearly encoded from genes located on separate chromosomes, and it is not yet understood how gene expression of the components is regulated to maintain proper stoichiometry of the complex. The focus of the present study is to establish mRNA half-lives for the BCKD subunits in two human cell lines and to examine whether expression of transcripts for the subunits is similar in different cell types. HepG2 cells, a hepatocarcinoma cell line, and DG75 cells, a Burkitt`s lymphoma cell line, express comparable levels of BCKD complex based on total enzyme activity. Half-lives of the mRNAs for each subunit have been determined in HepG2 cells and are presently being defined in DG75 cells. mRNA half-lives were calculated by quantifying message levels over a 24 hour period following an actinomycin D block. Transcripts for the BCKD subunits are relatively stable in HepG2 cells with mRNA half-lives for the E1{alpha} of 11 hours, E1{beta}, 24 hours and E2, 22 hours. Steady-state message levels have been analyzed in both cell lines by RNase protection and quantified as a percentage of total RNA. mRNA levels for all three subunits are higher in DG75 cells than in HepG2 cells (E1{alpha}, 4-fold; E1{beta}, 1.9-fold; E2, 1.8-fold). Preliminary data indicates that the half-life of the E1{alpha} transcript in DG75 cells is approximately 29 hours, and it is possible that differences in steady-state levels of the mRNAs are achieved through different half-lives of the transcripts. The relationship between transcript levels and protein levels for the three subunits is being examined in both cell types.

  4. Alpha decay properties of heavy and superheavy elements

    Indian Academy of Sciences (India)

    G M Carmel Vigila Bai and Umai Parvathiy region which is smoothly connected by a Yukawa plus exponential potential for the region after separation. Then the potential as a function of r (which is the centre of mass distance of the two spherical fragments) for the postscission region is given by. V (r) = Z1Z2e2 r. + Vn (r) − Q,.

  5. Charm Decays at BABAR

    International Nuclear Information System (INIS)

    Charles, M.

    2004-01-01

    The results of several studies of charmed mesons and baryons at BABAR are presented. First, searches for the rare decays D 0 → l + l - are presented and new upper limits on these processes are established. Second, a measurement of the branching fraction of the isospin-violating hadronic decay D* s (2112) + → D s + π 0 relative to the radiative decay D* s (2112) + → D s + γ is made. Third, the decays of D* sJ (2317) + and D sJ (2460) + mesons are studied and ratios of branching fractions are measured. Fourth, Cabibbo-suppressed decays of the Λ c + are examined and their branching fractions measured relative to Cabibbo-allowed modes. Fifth, the Χ c 0 is studied through its decays to Χ - π + and (Omega) - K + ; in addition to measuring the ratio of branching fractions for Χ c 0 produced from the c(bar c) continuum, the uncorrected momentum spectrum is measured, providing clear confirmation of Χ c 0 production in B decays

  6. Top-quark processes at NLO in production and decay

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, John M.; Ellis, R.Keith

    2012-04-01

    We describe the implementation of top production and decay processes in the parton-level Monte Carlo program MCFM. By treating the top quark as being on-shell, we can factorize the amplitudes for top-pair production, s-channel single-top production, and t-channel single-top production into the product of an amplitude for production and an amplitude for decay. In this way we can retain all spin correlations. Both the production and the decay amplitudes are calculated consistently at next-to-leading order in alpha_s. The full dependence on the b-quark mass is also kept. Phenomenological results are presented for various kinematic distributions at the LHC and for the top quark forward-backward asymmetry at the Tevatron.

  7. SYMPOSIUM: Rare decays

    International Nuclear Information System (INIS)

    Anon.

    1989-01-01

    Late last year, a symposium entitled 'Rare Decays' attracted 115 participants to a hotel in Vancouver, Canada. These participants were particle physicists interested in checking conventional selection rules to look for clues of possible new behaviour outside today's accepted 'Standard Model'. For physicists, 'rare decays' include processes that have so far not been seen, explicitly forbidden by the rules of the Standard Model, or processes highly suppressed because the decay is dominated by an easier route, or includes processes resulting from multiple transitions

  8. Weak radiative hyperon decays

    International Nuclear Information System (INIS)

    Roberts, B.L.; Booth, E.C.; Gall, K.P.; McIntyre, E.K.; Miller, J.P.; Whitehouse, D.A.; Bassalleck, B.; Hall, J.R.; Larson, K.D.; Wolfe, D.M.; Fickinger, W.J.; Robinson, D.K.; Hallin, A.L.; Hasinoff, M.D.; Measday, D.F.; Noble, A.J.; Waltham, C.E.; Hessey, N.P.; Lowe, J.; Horvath, D.; Salomon, M.

    1990-01-01

    New measurements of the Σ + and Λ weak radiative decays are discussed. The hyperons were produced at rest by the reaction K - p → Yπ where Y = Σ + or Λ. The monoenergetic pion was used to tag the hyperon production, and the branching ratios were determined from the relative amplitudes of Σ + → pγ to Σ + → pπ 0 and Λ → nγ to Λ → nπ 0 . The photons from weak radiative decays and from π 0 decays were detected with modular NaI arrays. (orig.)

  9. Non-leptonic decays of beauty decays

    CERN Document Server

    Bigi, Ikaros I; Shifman, M; Uraltsev, N; Vainshtein, A I

    1994-01-01

    "Anyone who keeps the ability to see beauty never grows old" (Franz Kafka). In the last few years considerable progress has been achieved in our understanding of the decays of heavy flavour hadrons. One can now calculate inclusive transition rates in QCD proper through an expansion in inverse powers of the heavy flavour quark mass without recourse to phenomenological assumptions. The non-perturbative contributions are treated systematically in this way; they are found to produce corrections of order a few percent in beauty decays, i.e. typically somewhat smaller than the perturbative corrections. One finds, among other things: (a) The lifetime of $B^-$ mesons is predicted to be longer than that of $B^0$ mesons by several percent. (b) The QCD prediction for the semileptonic branching ratio of $B$ mesons appears to exceed present experimental values.

  10. Workshop on High-precision $\\alpha_s$ measurements from LHC to FCC-ee

    CERN Document Server

    S. Alekhin; d'Enterria, David; A. Banfi; S. Bethke; J. Blümlein; K.G. Chetyrkin; D. d’Enterria; G. Dissertori; X. Garcia i Tormo; A. H. Hoang; M. Klasen; T. Klijnsma; S. Kluth; J.-L. Kneur; B.A. Kniehl; D. W. Kolodrubetz; J. Kühn; P. Mackenzie; B. Malaescu; V. Mateu; L. Mihaila; S. Moch; K. Mönig; R. Pérez-Ramos; A. Pich; J. Pires; K. Rabbertz; G. P. Salam; F. Sannino; J. Soto i Riera; M. Srebre; I. W. Stewart

    2015-01-01

    This document provides a writeup of all contributions to the workshop on "High precision measurements of $\\alpha_s$: From LHC to FCC-ee" held at CERN, Oct. 12--13, 2015. The workshop explored in depth the latest developments on the determination of the QCD coupling $\\alpha_s$ from 15 methods where high precision measurements are (or will be) available. Those include low-energy observables: (i) lattice QCD, (ii) pion decay factor, (iii) quarkonia and (iv) $\\tau$ decays, (v) soft parton-to-hadron fragmentation functions, as well as high-energy observables: (vi) global fits of parton distribution functions, (vii) hard parton-to-hadron fragmentation functions, (viii) jets in $e^\\pm$p DIS and $\\gamma$-p photoproduction, (ix) photon structure function in $\\gamma$-$\\gamma$, (x) event shapes and (xi) jet cross sections in $e^+e^-$ collisions, (xii) W boson and (xiii) Z boson decays, and (xiv) jets and (xv) top-quark cross sections in proton-(anti)proton collisions. The current status of the theoretical and experiment...

  11. arXiv Workshop on Precision Measurements of alphas

    CERN Document Server

    Bethke, S.; Kluth, S.; Schieck, J.; Stewart, I.W.; Aoki, S.; Beneke, M.; Blumlein, J.; Brambilla, N.; Brodsky, S.; Descotes-Genon, S.; Erler, J.; Forte, S.; Gehrmann, T.; Glasman, C.; Golterman, M.; Hashimoto, S.; Kronfeld, A.; Kuhn, J.; Lepage, P.; Martin, A.; Mateu, V.; Menke, S.; Nomura, Y.; Pahl, C.; Petriello, F.; Pich, A.; Rabbertz, K.; Salam, G.; Schulz, H.; Sommer, R.; Steinhauser, M.; Webber, B.; Yuan, CP.; Zanderighi, G.

    2011-01-01

    These are the proceedings of the "Workshop on Precision Measurements of alphas" held at the Max-Planck-Institute for Physics, Munich, February 9-11, 2011. The workshop explored in depth the determination of alphas(mZ) in the MS-bar scheme from the key categories where high precision measurements are currently being made, including DIS and global PDF fits, tau-decays, electroweak precision observables and Z-decays, event-shapes, and lattice QCD. These proceedings contain a short summary contribution from the speakers, as well as the lists of authors, conveners, participants, and talks.

  12. Decay data of the transactinium nuclides

    International Nuclear Information System (INIS)

    1986-01-01

    The report presents the results of the work undertaken from 1978 until 1985 by the participants in the IAEA Co-ordinated Research Programme (CRP) on the Measurement and Evaluation of Transactinium Isotope Nuclear Decay Data. They are given in the form of data tabulations with specific reference to the measurements and evaluations performed by the CRP participants and the data which they recommend for half-lives and branching fractions, gamma ray transition energies and emission probabilities and alpha radiation energies and emission probabilities. A complete set of recommended decay data for heavy nuclei, including data that originate from sources other than the CRP, is given in the last part of the report

  13. CKM Parameters and Rare B Decays

    Energy Technology Data Exchange (ETDEWEB)

    Forti, Francesco; /INFN, Pisa

    2005-12-14

    Measurements of the angles and sides of the unitarity triangle and of the rates of rare B meson decays are crucial for the precise determination of Standard Model parameters and are sensitive to the presence of new physics particles in the loop diagrams. In this paper the recent measurements performed in this area by BABAR and Belle will be presented. The direct measurement of the angle {alpha} is for the first time as precise as the indirect determination. The precision of the |V{sub ub}| determination has improved significantly with respect to previous measurement. New limits on B {yields} {tau}{nu} decays are presented, as well as updated measurements on b {yields} s radiative transitions and a new observation of b {yields} d{gamma} transition made by Belle.

  14. Inflaton decay in supergravity

    International Nuclear Information System (INIS)

    Endo, M.; Takahashi, F.; Yanagida, T.T.; Tokyo Univ.

    2007-06-01

    We discuss inflaton decay in supergravity, taking account of the gravitational effects. It is shown that, if the inflaton has a nonzero vacuum expectation value, it generically couples to any matter fields that appear in the superpotential at the tree level, and to any gauge sectors through anomalies in the supergravity. Through these processes, the inflaton generically decays into the supersymmetry breaking sector, producing many gravitinos. The inflaton also directly decays into a pair of the gravitinos. We derive constraints on both inflation models and supersymmetry breaking scenarios for avoiding overproduction of the gravitinos. Furthermore, the inflaton naturally decays into the visible sector via the top Yukawa coupling and SU(3) C gauge interactions. (orig.)

  15. Neutrinoless double beta decay

    Indian Academy of Sciences (India)

    Abstract. The physics potential of neutrinoless double beta decay is discussed. Furthermore, experimental considerations as well as the current status of experiments are presented. Finally, an outlook towards the future, work on nuclear matrix elements and alternative processes is given.

  16. The new isotope 270110 and its decay products 266Hs and 262Sg

    International Nuclear Information System (INIS)

    Hofmann, S.; Hessberger, F.P.; Ackermann, D.

    2000-11-01

    The even-even nucleus 270 110 was synthesized using the reaction 64 Ni + 207 Pb. A total of eight α-decay chains was measured during an irradiation time of seven days. Decay data were obtained for the ground-state and a high spin K isomer. The new nuclei 266 Hs and 262 Sg were identified as daughter products after α decay. Spontaneous fission of 262 Sg terminates the decay chain. The measured data are in agreement with calculations using the macroscopic-microscopic model and with self-consistent HFB calculations with Skyrme-Sly4 interaction. (orig.)

  17. Measurement of the asymmetry parameter for the decay $\\bar\\Lambda \\to \\bar p\\pi^+$

    OpenAIRE

    BES collaboration

    2009-01-01

    Based on a sample of $58\\times10^6J/\\psi$ decays collected with the BESII detector at the BEPC, the $\\bar\\Lambda$ decay parameter $\\alpha_{\\bar\\Lambda}$ for $\\bar\\Lambda\\to \\bar p \\pi^+$ is measured using about 9000 $J/\\psi\\to\\Lambda\\bar\\Lambda\\to p \\bar p \\pi^+\\pi^-$ decays. A fit to the joint angular distributions yields $\\alpha_{\\bar\\Lambda}(\\bar\\Lambda\\to \\bar p\\pi^+)=-0.755\\pm0.083\\pm0.063$, where the first error is statistical, and the second systematic.

  18. Streamer chamber: pion decay

    CERN Multimedia

    1992-01-01

    The real particles produced in the decay of a positive pion can be seen in this image from a streamer chamber. Streamer chambers consist of a gas chamber through which a strong pulsed electric field is passed, creating sparks as a charged particle passes through it. A magnetic field is added to cause the decay products to follow curved paths so that their charge and momentum can be measured.

  19. Aspects of B decays

    Energy Technology Data Exchange (ETDEWEB)

    Faller, Sven

    2011-03-04

    B-meson decays are a good probe for testing the flavour sector of the standard model of particle physics. The standard model describes at present all experimental data satisfactorily, although some ''tensions'' exist, i.e. two to three sigma deviations from the predictions, in particular in B decays. The arguments against the standard model are thus purely theoretical. These tensions between experimental data and theoretical predictions provide an extension of the standard model by new physics contributions. Within the flavour sector main theoretical uncertainties are related to the hadronic matrix elements. For exclusive semileptonic anti B {yields} D{sup (*)}l anti {nu} decays QCD sum rule techniques, which are suitable for studying hadronic matrix elements, however, with substantial, but estimable hadronic uncertainties, are used. The exploration of new physics effects in B-meson decays is done in an twofold way. In exclusive semileptonic anti B {yields} D{sup (*)}l anti {nu} decays the effect of additional right-handed vector as well as left- and right-handed scalar and tensor hadronic current structures in the decay rates and the form factors are studied at the non-recoil point. As a second approach one studied the non-leptonic B{sup 0}{sub s}{yields}J/{psi}{phi} and B{sup 0}{yields}J/{psi}K{sub S,L} decays discussing CP violating effects in the time-dependent decay amplitudes by considering new physics phase in the B{sup 0}- anti B{sup 0} mixing phase. (orig.)

  20. Tau decays into kaons

    International Nuclear Information System (INIS)

    Finkemeier, M.; Mirkes, E.

    1995-04-01

    Predictions for semi-leptonic decay rates of the τ lepton into two meson final states and three meson final states are derived. The hadronic matrix elements are expressed in terms of form factors, which can be predicted by chiral Lagrangians supplemented by informations about all possible low-lying resonances in the different channels. Isospin symmetry relations among the different final states are carefully taken into account. The calculated brancing ratios are compared with measured decay rates where data are available

  1. Calculated /alpha/-induced thick target neutron yields and spectra, with comparison to measured data

    International Nuclear Information System (INIS)

    Wilson, W.B.; Bozoian, M.; Perry, R.T.

    1988-01-01

    One component of the neutron source associated with the decay of actinide nuclides in many environments is due to the interaction of decay /alpha/ particles in (/alpha/,n) reactions on low Z nuclides. Measurements of (/alpha/,n) thick target neutron yields and associated neutron spectra have been made for only a few combinations of /alpha/ energy and target nuclide or mixtures of actinide and target nuclides. Calculations of thick target neutron yields and spectra with the SOURCES code require /alpha/-energy-dependent cross sections for (/alpha/,n) reactions, as well as branching fractions leading to the energetically possible levels of the product nuclides. A library of these data has been accumulated for target nuclides of Z /le/ 15 using that available from measurements and from recent GNASH code calculations. SOURCES, assuming neutrons to be emitted isotopically in the center-of-mass system, uses libraries of /alpha/ stopping cross sections, (/alpha/,n) reaction cross reactions, product nuclide level branching fractions, and actinide decay /alpha/ spectra to calculate thick target (/alpha/,n) yields and neutron spectra for homogeneous combinations of nuclides. The code also calculates the thick target yield and angle intergrated neutron spectrum produced by /alpha/-particle beams on targets of homogeneous mixtures of nuclides. Illustrative calculated results are given and comparisons are made with measured thick target yields and spectra. 50 refs., 1 fig., 2 tabs

  2. Current status and perspectives in alpha radioimmunotherapy.

    Science.gov (United States)

    Chérel, M; Davodeau, F; Kraeber-Bodéré, F; Chatal, J F

    2006-12-01

    Systemic administration of radiolabeled antibody directed against tumor antigens in radioimmunotherapy (RIT) enables to specifically target the cancer cells and to destroy them. So far, this strategy has proven its efficiency in the treatment of some hematological cancers with antibodies labeled with beta emitting radionuclides. In the last 2 decades, availability of short half life alpha emitters prompted to consider their use in RIT. Contrary to beta particles, alpha particles have a short path length and display a high lineic energy transfer. Those physical characteristics open new fields of clinical applications complementary to beta-RIT. To date, alpha-RIT is still at a preclinical stage of development: the radiolabeling methods need to be optimized to ensure in vivo stability of the radiopharmaceuticals. Some radionuclides have complex decay schemes with daughters emitting further alpha particles whose toxicity needs to be investigated. The modalities of administration of radiolabeled antibodies in animal models require also to be improved for delivering higher doses to tumor targets. A comprehensive analysis of the specific events occurring at cell or tissue level in response to alpha irradiation would be of great interest in order to define the best therapeutic association for residual disease or consolidation treatments. This approach has been proven to be efficient in increasing antitumor response either by using high doses with organ protection (kidney, bone marrow) or by a synergistic effect between alpha-RIT and associated treatments, such as chemotherapy.

  3. New Precise Measurements of the $\\Xi^{0} \\to \\Lambda \\gamma$ and $\\Xi^{0} \\to \\Sigma^{0}\\gamma$ Decay Asymmetries

    CERN Document Server

    Batley, J R; Lazzeroni, C; Munday, D J; Patel, M; Slater, M W; Wotton, S A; Arcidiacono, R; Bocquet, G; Ceccucci, A; Cundy, D; Doble, N; Falaleev, V; Gatignon, L; Gonidec, A; Grafstrom, P; Kubischta, W; Mikulec, I; Norton, A; Panzer-Steindel, B; Rubin, P; Wahl, H; Goudzovski, E; Hristov, P; Kekelidze, V; Litov, L; Madigozhin, D; Molokanova, N; Potrebenikov, Yu; Stoynev, S; Zinchenko, A; Monnier, E; Swallow, E; Winston, R; Sacco, R; Walker, A; Baldini, W; Gianoli, A; Dalpiaz, P; Frabetti, P L; Martini, M; Petrucci, F; Savrie, M; Scarpa, M; Calvetti, M; Collazuol, G; Iacopini, E; Ruggiero, G; Bizzeti, A; Lenti, M; Veltri, M; Behler, M; Eppard, K; Eppard, M; Hirstius, A; Kleinknecht, K; Koch, U; Marouelli, P; Masetti, L; Moosbrugger, U; Morales-Morales, C; Peters, A; Wanke, R; Winhart, A; Dabrowski, A; Fonseca Martin, T; Velasco, M; Cenci, P; Lubrano, P; Pepe, M; Anzivino, G; Imbergamo, E; Lamanna, G; Michetti, A; Nappi, A; Petrucci, M C; Piccini, M; Valdata, M; Cerri, C; Fantechi, R; Costantini, F; Fiorini, L; Giudici, S; Pierazzini, G; Sozzi, M; Mannelli, I; Cheshkov, C; Cheze, J B; De Beer, M; Debu, P; Gouge, G; Marel, G; Mazzucato, E; Peyaud, B; Vallage, B; Holder, M; Maier, A; Ziolkowski, M; Biino, C; Cartiglia, N; Marchetto, F; Pastrone, N; Clemencic, M; Goy Lopez, S; Menichetti, E; Wislicki, W; Dibon, H; Jeitler, M; Markytan, M; Neuhofer, G; Widhalm, L

    2010-01-01

    The decay asymmetries of the weak radiative Hyperon decays $\\Xi^{0}\\to \\Lambda \\gamma$ and $\\Xi^{0} \\to \\Sigma^{0}\\gamma$ have been measured with high precision using data of the NA48/1 experiment at CERN. From about 52000 $\\Xi^{0}\\to \\Lambda \\gamma$ and 15000 $\\Xi^{0} \\to \\Sigma^{0}\\gamma$ decays, we obtain for the decay asymmetries $\\alpha_{\\Xi^{0}\\to \\Lambda\\gamma}$ = -0.704 +- 0.019$_{stat}$ +- 0.064$_{syst}$ and $\\alpha_{\\Xi^{0}\\to \\Sigma^{0}\\gamma}$ = -0.729 +- 0.030$_{stat}$ +- 0.076$_{syst}$, respectively. These results are in good agreement with previous experiments, but more precise.

  4. Compilations and evaluations of nuclear structure and decay data

    International Nuclear Information System (INIS)

    Lorenz, A.

    1977-03-01

    This is the second issue of a report series on published and to-be-published compilations and evaluations of nuclear structure and decay (NSD) data. This compilation of compilations and evaluations is designed to keep the nuclear scientific community informed of the availability of compiled or evaluated NSD data, and contains references to laboratory reports, journal articles and books containing selected compilations and evaluations. It excludes references to ''mass-chain'' evaluations normally published in the ''Nuclear Data Sheets'' and ''Nuclear Physics''. The material contained in this compilation is sorted according to eight subject categories: general compilations; basic isotopic properties; nuclear structure properties; nuclear decay processes; half-lives, energies and spectra; nuclear decay processes: gamma-rays; nuclear decay processes: fission products; nuclear decay processes: (others); atomic processes

  5. Low energy alphas in the drift detector

    International Nuclear Information System (INIS)

    Snowden-Ifft, D.P.; Lawson, T.; Spooner, N.J.C.; Villaume, N.

    2004-01-01

    The Directional Recoil Identification From Tracks project is a US-UK endeavor to build and operate a low pressure negative ion TPC (NITPC) to search for weakly interacting massive particles (WIMPs) thought to make up the dark matter in our Galaxy. Low energy (∼10 keV) alpha events from U and Th decays within the walls and wires of the detector can enter the active volume of the detector and be confused for WIMP interactions. This paper presents data on and a model of low energy alphas in a NITPC operated at 40 Torr CS 2 with the aim of understanding and removing this potentially serious background. A comparison of the data to this model reveals good agreement with range predictions of SRIM2000 and allows us to calculate the energy dissipation per ion pair, W=19.0±0.5 eV for low energy alphas in CS 2

  6. Markov chains

    CERN Document Server

    Revuz, D

    1984-01-01

    This is the revised and augmented edition of a now classic book which is an introduction to sub-Markovian kernels on general measurable spaces and their associated homogeneous Markov chains. The first part, an expository text on the foundations of the subject, is intended for post-graduate students. A study of potential theory, the basic classification of chains according to their asymptotic behaviour and the celebrated Chacon-Ornstein theorem are examined in detail. The second part of the book is at a more advanced level and includes a treatment of random walks on general locally compact abelian groups. Further chapters develop renewal theory, an introduction to Martin boundary and the study of chains recurrent in the Harris sense. Finally, the last chapter deals with the construction of chains starting from a kernel satisfying some kind of maximum principle.

  7. The analysis of natural uranium decay based on gamma-ray measurements

    International Nuclear Information System (INIS)

    Kim, K. W.; Kim, D. G.; No, W. S.; Park, P. W.; Yang, S. W.; Park, G. H.

    2004-01-01

    Measurements of gamma-radiations from natural uranium dioxide were performed to analyze the decay chain of natural uranium. 10.1g of natural uranium dioxide was used as a specimen and the measurement was done for 24 hours. Genie-2000 was used for the analysis of gamma ray energy from uranium. Theoretical estimation of gamma rays from the decay chain and data from the measurement were compared quantitatively. Based on these comparisons, the gamma rays from the decay chain of natural uranium were analyzed

  8. Strength loss in decayed wood

    Science.gov (United States)

    Rebecca E. Ibach; Patricia K. Lebow

    2014-01-01

    Wood is a durable engineering material when used in an appropriate manner, but it is susceptible to biological decay when a log, sawn product, or final product is not stored, handled, or designed properly. Even before the biological decay of wood becomes visually apparent, the decay can cause the wood to become structurally unsound. The progression of decay to that...

  9. CP violation in B decay

    OpenAIRE

    Yamamoto, Hitoshi

    2001-01-01

    We review the physics of CP violation in B decays. After introducing the CKM matrix and how it causes CP violation, we cover three types of CP violation that can occur in B decays: CP violation in mixing, CP violation by mixing-decay interference, and CP violation in decay.

  10. Decay-Assisted Laser Spectroscopy of Neutron-Deficient Francium

    Directory of Open Access Journals (Sweden)

    K. M. Lynch

    2014-03-01

    Full Text Available This paper reports on the hyperfine-structure and radioactive-decay studies of the neutron-deficient francium isotopes ^{202–206}Fr performed with the Collinear Resonance Ionization Spectroscopy (CRIS experiment at the ISOLDE facility, CERN. The high resolution innate to collinear laser spectroscopy is combined with the high efficiency of ion detection to provide a highly sensitive technique to probe the hyperfine structure of exotic isotopes. The technique of decay-assisted laser spectroscopy is presented, whereby the isomeric ion beam is deflected to a decay-spectroscopy station for alpha-decay tagging of the hyperfine components. Here, we present the first hyperfine-structure measurements of the neutron-deficient francium isotopes ^{202–206}Fr, in addition to the identification of the low-lying states of ^{202,204}Fr performed at the CRIS experiment.

  11. Decay-Assisted Laser Spectroscopy of Neutron-Deficient Francium

    CERN Document Server

    Lynch, K M; Bissell, M L; Budincevic, I; Cocolios, T E; De Groote, R P; De Schepper, S; Fedosseev, V N; Flanagan, K T; Franchoo, S; Garcia Ruiz, R F; Heylen, H; Marsh, B A; Neyens, G; Procter, T J; Rossel, R E; Rothe, S; Strashnov, I; Stroke, H H; Wendt, K D A

    2014-01-01

    This paper reports on the hyperfine-structure and radioactive-decay studies of the neutron-deficient francium isotopes $^{202-206}$Fr performed with the Collinear Resonance Ionization Spectroscopy (CRIS) experiment at the ISOLDE facility, CERN. The high resolution innate to collinear laser spectroscopy is combined with the high efficiency of ion detection to provide a highly-sensitive technique to probe the hyperfine structure of exotic isotopes. The technique of decay-assisted laser spectroscopy is presented, whereby the isomeric ion beam is deflected to a decay spectroscopy station for alpha-decay tagging of the hyperfine components. Here, we present the first hyperfine-structure measurements of the neutron-deficient francium isotopes $^{202-206}$Fr, in addition to the identification of the low-lying states of $^{202,204}$Fr performed at the CRIS experiment.

  12. Experimental investigation of decay properties of neutron deficient $^{116-118}$Ba isotopes and test of $^{112-115}$Ba beam counts

    CERN Multimedia

    We propose to study decay of neutron deficient isotopes $^{116-118}$Ba using Double Sided Silicon Strip Detector (DSSSD). To study delayed-proton and $\\alpha$-decay branching ratios of $^{116-118}$Ba are of special interest because of their vicinity to the proton drip line. The nuclear life-times and properties of the proton unstable states of Cs isotopes, populated through decay of $^{116-118}$Ba isotopes will be measured. In addition to that we propose beam development of $^{112-115}$Ba to study exotic decay properties of these neutron deficient nuclei and to search for super-allowed $\\alpha$-decay in future.

  13. Alpha decay and cluster decay of some neutron-rich actinide nuclei

    Indian Academy of Sciences (India)

    Our model has a cubic potential for the overlapping region which is smoothly connected by a Yukawa plus exponential potential for the region after separation. The computed half-lives are compared with those of other theoretical models and are found to be in good agreement with each other. In this work, we have also ...

  14. Alpha decay and cluster decay of some neutron-rich actinide nuclei

    Indian Academy of Sciences (India)

    2017-02-09

    Feb 9, 2017 ... plus Yukawa plus exponential model (CYEM). Our model has a cubic potential for the overlapping region which is smoothly connected by a Yukawa plus exponential potential for the region after separation. The computed half-lives are compared with those of other theoretical models and are found to be in ...

  15. CHAIN 2

    International Nuclear Information System (INIS)

    Bailey, D.

    1998-04-01

    The Second Processing Chain (CHAIN2) consists of a suite of ten programs which together provide a full local analysis of the bulk plasma physics within the JET Tokamak. In discussing these ten computational models this report is intended to fulfil two broad purposes. Firstly it is meant to be used as a reference source for any user of CHAIN2 data, and secondly it provides a basic User Manual sufficient to instruct anyone in running the CHAIN2 suite of codes. In the main report text each module is described in terms of its underlying physics and any associated assumptions or limitations, whilst deliberate emphasis is put on highlighting the physics and mathematics of the calculations required in deriving each individual datatype in the standard module PPF output. In fact each datatype of the CHAIN2 PPF output listed in Appendix D is cross referenced to the point in the main text where its evaluation is discussed. An effort is made not only to give the equation used to derive a particular data profile but also to explicitly define which external data sources are involved in the computational calculation

  16. Germanium cryogenic detectors: Alpha surface events rejection capabilities

    International Nuclear Information System (INIS)

    Fiorucci, S.; Broniatowski, A.; Chardin, G.; Censier, B.; Lesquen, A. de; Deschamps, H.; Fesquet, M.; Jin, Y.

    2006-01-01

    Alpha surface events and multiple compton gamma interactions are the two major background components in Ge detectors for double-beta decay investigations. Two different methods have been studied to identify such type of events, using cryogenic Ge detectors developed primarily for dark matter search: (i) combined heat and ionization measurements, and (ii) pulse-shape analysis of the charge collection signals. Both methods show strong separation between electron recoil events and surface alphas. Cryogenic heat-ionization detectors therefore appear able to reject virtually all surface alpha interactions

  17. MEASUREMENTS OF AIRBORNE CONCENTRATIONS OF RADON AND THORON DECAY PRODUCTS.

    Science.gov (United States)

    Chalupnik, S; Skubacz, K; Urban, P; Wysocka, M

    2017-11-01

    Liquid scintillation counting (LSC) is a measuring technique, broadly applied in environmental monitoring of radionuclides. One of the possible applications of LSC is the measurement of radon and thoron decay products. But this method is suitable only for grab sampling. For long-term measurements a different technique can be applied-monitors of potential alpha energy concentration (PAEC) with thermoluminescent detectors (TLD). In these devices, called Alfa-2000 sampling probe, TL detectors (CaSO4:Dy) are applied for alpha particles counting. Three independent heads are placed over the membrane filter in a dust sampler's microcyclone. Such solution enables simultaneous measurements of PAEC and dust content. Moreover, the information which is stored in TLD chips is the energy of alpha particles, not the number of counted particles. Therefore, the readout of TL detector shows directly potential alpha energy, with no dependence on equilibrium factor, etc. This technique, which had been used only for radon decay products measurements, was modified by author to allow simultaneous measurements of radon and thoron PAEC. The LSC method can be used for calibration of portable radon decay products monitors. The LSC method has the advantage to be an absolute one, the TLD method to measure directly the (dose relevant) deposited energy. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  18. Decay of 49Cr

    International Nuclear Information System (INIS)

    Jackson, S.V.; Henry, E.A.; Meyer, R.A.

    1975-01-01

    For the decay of 49 Cr the intensities of the 1361-, 1423-, 1508-, 1514-, and 1570-keV γ rays are found to be 0.85, 0.19, 0.15, 0.49, and 0.37, respectively, relative to I/sub gamma/ = 1000 for the 90-keV γ ray. Four other previously reported γ rays are shown to be sum peaks or contaminants. The recalculated β-decay branches and logft values (in parentheses) for 49 Cr decay are ground state (5.51), 90.639- (4.94), 152.928- (4.74), 1514.5- (5.71), 1661.1- (6.06), 2181.7- (7.0), 2236- (6.6), and 2310-keV (7.1). The known 3/2 + level at 748 keV was not observed to be populated and a limit of logft > 9 was found for that level

  19. Beta and muon decays

    Energy Technology Data Exchange (ETDEWEB)

    Galindo, A.; Pascual, P.

    1967-07-01

    These notes represent a series of lectures delivered by the authors in the Junta de Energia Nuclear, during the Spring term of 1965. They were devoted to graduate students interested in the Theory of Elementary Particles. Special emphasis was focussed into the computational problems. Chapter I is a review of basic principles (Dirac equation, transition probabilities, final state interactions.) which will be needed later. In Chapter II the four-fermion punctual Interaction is discussed, Chapter III is devoted to the study of beta-decay; the main emphasis is given to the deduction of the formulae corresponding to electron-antineutrino correlation, electron energy spectrum, lifetimes, asymmetry of electrons emitted from polarized nuclei, electron and neutrino polarization and time reversal invariance in beta decay. In Chapter IV we deal with the decay of polarized muons with radiative corrections. Chapter V is devoted to an introduction to C.V.C. theory. (Author)

  20. Suppressed Charmed B Decay

    Energy Technology Data Exchange (ETDEWEB)

    Snoek, Hella Leonie [Vrije Univ., Amsterdam (Netherlands)

    2009-06-02

    This thesis describes the measurement of the branching fractions of the suppressed charmed B0 → D*- a0+ decays and the non-resonant B0 → D*- ηπ+ decays in approximately 230 million Υ(4S) → B$\\bar{B}$ events. The data have been collected with the BABAR detector at the PEP-II B factory at the Stanford Linear Accelerator Center in California. Theoretical predictions of the branching fraction of the B0 → D*- a{sub 0}+ decays show large QCD model dependent uncertainties. Non-factorizing terms, in the naive factorization model, that can be calculated by QCD factorizing models have a large impact on the branching fraction of these decay modes. The predictions of the branching fractions are of the order of 10-6. The measurement of the branching fraction gives more insight into the theoretical models. In general a better understanding of QCD models will be necessary to conduct weak interaction physics at the next level. The presence of CP violation in electroweak interactions allows the differentiation between matter and antimatter in the laws of physics. In the Standard Model, CP violation is incorporated in the CKM matrix that describes the weak interaction between quarks. Relations amongst the CKM matrix elements are used to present the two relevant parameters as the apex of a triangle (Unitarity Triangle) in a complex plane. The over-constraining of the CKM triangle by experimental measurements is an important test of the Standard Model. At this moment no stringent direct measurements of the CKM angle γ, one of the interior angles of the Unitarity Triangle, are available. The measurement of the angle γ can be performed using the decays of neutral B mesons. The B0 → D*- a0+ decay is sensitive to the angle γ and, in comparison to the current decays that are being employed, could significantly

  1. Decay of superdeformed bands

    International Nuclear Information System (INIS)

    Carpenter, M.P.; Khoo, T.L.; Lauritsen, T.

    1995-01-01

    One of the major challenges in the study of superdeformation is to directly connect the large number of superdeformed bands now known to the yrast states. In this way, excitation energies, spins and parities can be assigned to the levels in the second well which is essential to establish the collective and single-particle components of these bands. This paper will review some of the progress which has been made to understand the decay of superdeformed bands using the new arrays including the measurement of the total decay spectrum and the establishment of direct one-step decays from the superdeformed band to the yrast line in 194 Hg. 42 refs., 5 figs

  2. Weak interactions: muon decay

    International Nuclear Information System (INIS)

    Sachs, A.M.; Sirlin, A.

    1975-01-01

    The traditional theory of the dominant mode of muon decay is presented, a survey of the experiments which have measured the observable features of the decay is given, and those things which can be learned about the parameters and nature of the theory from the experimental results are indicated. The following aspects of the theory of muon decay are presented first: general four-fermion theory, two-component theory of the neutrino, V--A theory, two-component and V--A theories vs general four-fermion theory, intermediate-boson hypothesis, radiative corrections, radiative corrections in the intermediate-boson theory, and endpoint singularities and corrections of order α 2 . Experiments on muon lifetime, isotropic electron spectrum, total asymmetry and energy dependence of asymmetry of electrons from polarized muons, and electron polarization are described, and a summary of experimental results is given. 7 figures, 2 tables, 109 references

  3. Tunnel current across linear homocatenated germanium chains

    International Nuclear Information System (INIS)

    Matsuura, Yukihito

    2014-01-01

    The electronic transport properties of germanium oligomers catenating into linear chains (linear Ge chains) have been theoretically studied using first principle methods. The conduction mechanism of a Ge chain sandwiched between gold electrodes was analyzed based on the density of states and the eigenstates of the molecule in a two-probe environment. Like that of silicon chains (Si chains), the highest occupied molecular orbital of Ge chains contains the extended σ-conjugation of Ge 4p orbitals at energy levels close to the Fermi level; this is in contrast to the electronic properties of linear carbon chains. Furthermore, the conductance of a Ge chain is expected to decrease exponentially with molecular length L. The decay constant β, which is defined as e −βL , of a Ge chain is similar to that of a Si chain, whereas the conductance of the Ge chains is higher than that of Si chains even though the Ge–Ge bond length is longer than the Si–Si bond length

  4. Do protons decay

    International Nuclear Information System (INIS)

    Litchfield, P.J.

    1984-09-01

    The experimental status of proton decay is reviewed after the Leipzig International conference, July 1984. A brief comparative description of the currently active experiments is given. From the overall samples of contained events it can be concluded that the experiments are working well and broadly agree with each other. The candidates for proton decay from each experiment are examined. Although several experiments report candidates at a higher rate than expected from background calculations, the validity of these calculations is still open to doubt. (author)

  5. BEH fermionic decays

    CERN Document Server

    Dell'Asta, Lidia; The ATLAS collaboration

    2016-01-01

    Since the discovery of a Higgs-like boson by the ATLAS and CMS experiments at the LHC, the emphasis has shifted towards measurements of its properties and the search in the less sensitive channels in order to determine whether the new particle is the Standard Model (SM) Higgs boson. Of particular importance is the direct observation of the coupling of the Higgs boson to fermions. In this presentation a review of ATLAS and CMS results in the search for the Higgs boson in muon, tau-lepton, b-quark pair decay channels will be given. Moreover, the searches for lepton flavor violating decays will be presented.

  6. Palladium alpha-lipoic acid complex formulation enhances activities of Krebs cycle dehydrogenases and respiratory complexes I-IV in the heart of aged rats.

    Science.gov (United States)

    Sudheesh, N P; Ajith, T A; Janardhanan, K K; Krishnan, C V

    2009-08-01

    Age-related decline in the capacity to withstand stress, such as ischemia and reperfusion, results in congestive heart failure. Though the mechanisms underlying cardiac decay are not clear, age dependent somatic damages to mitochondrial DNA (mtDNA), loss of mitochondrial function, and a resultant increase in oxidative stress in heart muscle cells may be responsible for the increased risk for cardiovascular diseases. The effect of a safe nutritional supplement, POLY-MVA, containing the active ingredient palladium alpha-lipoic acid complex, was evaluated on the activities of the Krebs cycle enzymes such as isocitrate dehydrogenase, alpha-ketoglutarate dehydrogenase, succinate dehydrogenase, and malate dehydrogenase as well as mitochondrial complexes I, II, III, and IV in heart mitochondria of aged male albino rats of Wistar strain. Administration of 0.05 ml/kg of POLY-MVA (which is equivalent to 0.38 mg complexed alpha-lipoic acid/kg, p.o), once daily for 30 days, was significantly (pKrebs cycle dehydrogenases, and mitochondrial electron transport chain complexes. The unique electronic and redox properties of palladium alpha-lipoic acid complex appear to be a key to this physiological effectiveness. The results strongly suggest that this formulation might be effective to protect the aging associated risk of cardiovascular and neurodegenerative diseases.

  7. Radiological hazards of alpha-contaminated waste

    International Nuclear Information System (INIS)

    Rodgers, J.C.

    1982-01-01

    The radiological hazards of alpha-contaminated wastes are discussed in this overview in terms of two components of hazard: radiobiological hazard, and radioecological hazard. Radiobiological hazard refers to human uptake of alpha-emitters by inhalation and ingestion, and the resultant dose to critical organs of the body. Radioecological hazard refers to the processes of release from buried wastes, transport in the environment, and translocation to man through the food chain. Besides detailing the sources and magnitude of hazards, this brief review identifies the uncertainties in their estimation, and implications for the regulatory process

  8. Alpha radioactivity for proton-rich even Pb isotopes

    Indian Academy of Sciences (India)

    In choosing the model parameters we are guided by the following considerations: In naive calculations barrier height should correspond to Coulomb plus centrifu- gal potentials, but earlier studies have shown that various renormalization effects tend to lower this value. Royer [8] has modified the alpha decay barrier height.

  9. Decay properties of {sup 257}No, {sup 261}Rf, and {sup 262}Rf

    Energy Technology Data Exchange (ETDEWEB)

    Lazarev, Yu. A.; Lobanov, Yu. V.; Oganessian, Yu. Ts.; Utyonkov, V. K.; Abdullin, F. Sh.; Polyakov, A. N.; Rigol, J.; Shirokovsky, I. V.; Tsyganov, Yu. S.; Iliev, S. (and others)

    2000-12-01

    In bombardments of {sup 244}Pu targets with 114- and 120-MeV {sup 22}Ne projectiles we detected 69 {alpha}-{alpha} correlations linking {alpha} decays of {sup 261}Rf and {sup 257}No. We observed one {alpha} peak with E{sub {alpha}}=8.30{+-}0.06 MeV for {sup 261}Rf and peaks with {alpha}-particle energies 8.07--8.40 MeV for {sup 257}No. The half-life of {sup 257}No was measured to be 25{+-}3 s. No correlations were found between {alpha} decays and subsequent spontaneous fission events, from which we calculated an upper limit of 1.5% for the fission branch of {sup 257}No and estimated an upper limit of 3% for the {alpha}-decay branch of {sup 262}Rf. The cross section of the {sup 244}Pu({sup 22}Ne,5n){sup 261}Rf reaction was measured to be about 4 nb at both {sup 22}Ne energies used. We also report on some results from {sup 242}Pu+{sup 22}Ne and {sup 238}U+{sup 26}Mg bombardments.

  10. Automated generation of burnup chain for reactor analysis applications

    International Nuclear Information System (INIS)

    Tran, Viet-Phu; Tran, Hoai-Nam; Yamamoto, Akio; Endo, Tomohiro

    2017-01-01

    This paper presents the development of an automated generation of burnup chain for reactor analysis applications. Algorithms are proposed to reevaluate decay modes, branching ratios and effective fission product (FP) cumulative yields of a given list of important FPs taking into account intermediate reactions. A new burnup chain is generated using the updated data sources taken from the JENDL FP decay data file 2011 and Fission yields data file 2011. The new burnup chain is output according to the format for the SRAC code system. Verification has been performed to evaluate the accuracy of the new burnup chain. The results show that the new burnup chain reproduces well the results of a reference one with 193 fission products used in SRAC. Burnup calculations using the new burnup chain have also been performed based on UO 2 and MOX fuel pin cells and compared with a reference chain th2cm6fp193bp6T.

  11. Proton decay in intersecting D-brane models

    Energy Technology Data Exchange (ETDEWEB)

    Klebanov, Igor R. E-mail: klebanov@feynman.princeton.edu; Witten, Edward E-mail: witten@ias.edu

    2003-08-04

    We analyze proton decay via dimension-six operators in certain GUT-like models derived from Type IIA orientifolds with D6-branes. The amplitude is parametrically enhanced by a factor of {alpha}{sub GUT}{sup -1/3} relative to the corresponding result in four-dimensional GUTs. Nonetheless, even assuming a plausible enhancement from the threshold corrections, we find little overall enhancement of the proton decay rate from dimension-six operators, so that the predicted lifetime from this mechanism remains close to 10{sup 36} years.

  12. Kinetics of luminescence decay in electron-irradiated sapphire crystals

    Energy Technology Data Exchange (ETDEWEB)

    Caulfield, Kevin J.; Cooper, Ronald [Department of Chemistry, University of Melbourne, Parkville, VIC (Australia); Boas, John F. [Australian Radiation Laboratory, Yallambie, VIC (Australia)

    1997-07-28

    The kinetics of luminescence decay in electron-irradiated sapphire ({alpha}-Al{sub 2}O{sub 3}) single crystals have been investigated using time-resolved luminescence spectroscopy. The data, observed over timescales from tens of nanoseconds to tens of milliseconds, characteristically feature a rapid decay of intensity punctuated by discrete plateau regions. Simple theoretical models, invoking such theories as first- or second-order mechanisms, rate laws or power-law dependences, are unable to explain these features. A theoretical model comprising bimolecular electron - hole recombination, together with unimolecular electron detrapping from two discrete traps, qualitatively accounts for these features. (author)

  13. Upsilon family decays

    Energy Technology Data Exchange (ETDEWEB)

    Coyne, D.G.

    1984-10-01

    Selected topics in the investigations of decays of members of the Upsilon family are examined; the confrontation of theory with experiment is not yet adequate. The current evidence regarding the zeta(8322 MeV) is reviewed and future directions of study are indicated. 15 references.

  14. Teleportation via decay

    Indian Academy of Sciences (India)

    Abstract. We present a rare example of a decay mechanism playing a constructive role in quantum information processing. We show how the state of an atom trapped in a cavity can be teleported to a second atom trapped in a distant cavity by the joint detection of photon leakage from the cavities. The scheme, which is ...

  15. Teleportation via decay

    Indian Academy of Sciences (India)

    2015-11-27

    Nov 27, 2015 ... We present a rare example of a decay mechanism playing a constructive role in quantum information processing. We show how the state of an atom trapped in a cavity can be teleported to a second atom trapped in a distant cavity by the joint detection of photon leakage from the cavities. The scheme, which ...

  16. Unparticles and muon decay

    International Nuclear Information System (INIS)

    Choudhury, Debajyoti; Ghosh, Dilip Kumar; Mamta

    2008-01-01

    Recently Georgi has discussed the possible existence of 'Unparticles' describable by operators having non-integral scaling dimensions. With the interaction of these with the Standard Model particles being constrained only by gauge and Lorentz symmetries, it affords a new source for lepton flavour violation. Current and future muon decay experiments are shown to be very sensitive to such scenarios

  17. Unparticles and muon decay

    Energy Technology Data Exchange (ETDEWEB)

    Choudhury, Debajyoti [Department of Physics and Astrophysics, University of Delhi, Delhi 110 007 (India); Ghosh, Dilip Kumar [Department of Physics and Astrophysics, University of Delhi, Delhi 110 007 (India)], E-mail: dkghosh@physics.du.ac.in; Mamta [Department of Physics, S.G.T.B. Khalsa College, University of Delhi, Delhi 110 007 (India)

    2008-01-03

    Recently Georgi has discussed the possible existence of 'Unparticles' describable by operators having non-integral scaling dimensions. With the interaction of these with the Standard Model particles being constrained only by gauge and Lorentz symmetries, it affords a new source for lepton flavour violation. Current and future muon decay experiments are shown to be very sensitive to such scenarios.

  18. On the proton decay

    International Nuclear Information System (INIS)

    Fonda, L.; Ghirardi, G.C.; Weber, T.

    1983-07-01

    The problem of the proton decay is considered taking into account that in actual experiments there is an interaction of the proton with its environment which could imply an increase of its theoretical lifetime. It is seen that, by application of the time-energy uncertainty relation, no prolongation of the lifetime is obtained in this case. (author)

  19. B decays and supersymmetry

    Indian Academy of Sciences (India)

    be quantified later. All SUSY models available in the market can be divided into two broad categories: R- .... β. ¼ =β +φSUSY, α. ¼ =α φSUSY. (2) so that their sum remains unchanged. γ measured from Bs decays will also be changed by a different amount, and hence the unitarity triangle (UT) will not close: this is the signal.

  20. Decay ring status / studies

    CERN Document Server

    Chance, A

    2008-01-01

    The aim of "beta-beams" is to produce highly energetic pure electron neutrino and anti-neutrino beams coming from β-decay of radioactive ions. In CERN baseline, after accelerating, the ions 6He2+ and 18Ne10+ are stored in a racetrack-shaped-decay ring until they are lost [1]. Consequently, the injection compensates the losses which occurred between two cycles. Two main loss sources were identified: the β decay and the injection scheme. After giving the optics, we will see how to protect the magnetic elements from the decay products. The injections scheme will be then detailed with its implications. We will see that the injection process makes a collimation section in energy necessary. Since the magnetic elements are not perfect, we will take into account the magnet misalignment and the multipole defects in the dipoles. We will talk then about the closed orbit distortion due to misalignment defects and about the long-term transverse stability with the dynamic aperture.

  1. Neutrinoless double beta decay

    Indian Academy of Sciences (India)

    2012-10-06

    Oct 6, 2012 ... 2003 [13], the measured averaged 2νββ-decay half-lives as recommended in [14] plus the recent measurement of 136Xe [15,24]. The last column shows the experiments addressing the measurement of the corresponding isotope. For some experiments, only the 'default' isotope is mentioned as they have ...

  2. Nuclear double beta decay

    International Nuclear Information System (INIS)

    Hubert, P.; Mennrath, P.

    1985-01-01

    The processes of double beta decay with and without emission of neutrinos are briefly reviewed. After the definitions of the processes and implications for the neutrino properties, the present status of the experimental results is discussed. We conclude with a description of the Bordeaux-Zaragoza-Strasbourg experimental which will run in the Frejus tunnel

  3. B decays to baryons

    Indian Academy of Sciences (India)

    2012-11-10

    Nov 10, 2012 ... Figure 3. Effective Feynman diagrams for the initial meson–meson configuration. Figure 4. Effective Feynman diagrams for the initial diquark–antidiquark configuration. explain the absence of a threshold enhancement in B decays to baryons. There, all con- tributing Feynman diagrams are divided into two ...

  4. The determination of $\\alpha_s$ by the ALPHA collaboration

    CERN Document Server

    Bruno, Mattia

    2016-01-01

    We review the ALPHA collaboration strategy for obtaining the QCD coupling at high scale. In the three-flavor effective theory it avoids the use of perturbation theory at $\\alpha > 0.2$ and at the same time has the physical scales small compared to the cutoff $1/a$ in all stages of the computation. The result $\\Lambda_\\overline{MS}^{(3)}=332(14)$~MeV is translated to $\\alpha_\\overline{MS}(m_Z)=0.1179(10)(2)$ by use of (high order) perturbative relations between the effective theory couplings at the charm and beauty quark "thresholds". The error of this perturbative step is discussed and estimated as $0.0002$.

  5. Development of decay energy spectroscopy using low temperature detectors.

    Science.gov (United States)

    Jang, Y S; Kim, G B; Kim, K J; Kim, M S; Lee, H J; Lee, J S; Lee, K B; Lee, M K; Lee, S J; Ri, H C; Yoon, W S; Yuryev, Y N; Kim, Y H

    2012-09-01

    We have developed a high-resolution detection technique for measuring the energy and activity of alpha decay events using low-temperature detectors. A small amount of source material containing alpha-emitting radionuclides was enclosed in a 4π metal absorber. The energy of the alpha particles as well as that of the recoiled nuclides, low-energy electrons, and low-energy x-rays and γ-rays was converted into thermal energy of the gold absorber. A metallic magnetic calorimeter serving as a fast and sensitive thermometer was thermally attached to the metal absorber. In the present report, experimental demonstrations of Q spectroscopy were made with a new meander-type magnetic calorimeter. The thermal connection between the temperature sensor and the absorber was established with annealed gold wires. Each alpha decay event in the absorber resulted in a temperature increase of the absorber and the temperature sensor. Using the spectrum measured for a drop of (226)Ra solution in a 4π gold absorber, all of the alpha emitters in the sample were identified with a demonstration of good detector linearity. The resolution of the (226)Ra spectrum showed a 3.3 keV FWHM at its Q value together with an expected gamma escape peak at the energy shifted by its γ-ray energy. Copyright © 2012 Elsevier Ltd. All rights reserved.

  6. Code ACTIVE for calculation of the transmutation, induced activity and decay heat in neutron irradiation

    International Nuclear Information System (INIS)

    Ioki, Kimihiro; Harada, Yuhei; Asami, Naoto.

    1976-03-01

    The computer code ACTIVE has been prepared for calculation of the transmutation rate, induced activity and decay heat. Calculations are carried out with activation chain and spatial distribution of neutron energy spectrum. The spatial distribution of secondary gamma-ray source due to the unstable nuclides is also obtainable. Special attension is paid to the short life decays. (auth.)

  7. Present status of radiochemical double beta decay study (238U)

    International Nuclear Information System (INIS)

    Madic, C.; Maillard, C.; Chevallier, A.; Chevallier, J.; Escoubes, B.; Schulz, N.; Sens, J.C.

    1989-01-01

    A sensitive experiment has been designed that will be able to measure an assumed half-life of 1.9x10 22 yr. This double beta corresponds to the activity of 27000 238 Pu nuclei formed during a year, in a 200 m deep mine, from 300 kg of 238 U, giving 210 alpha decays per year. Plutonium 238 et 239 will be determined by alpha spectroscopy after extraction chromatography. Experimental studies were undertaken to select the best conditions for running the extraction chromatography cycles

  8. Modeling Radioactive Decay Chains with Branching Fraction Uncertainties

    Science.gov (United States)

    2013-03-01

    the numerical integration solution and the program had maximums of 10 -2 . 39 Performance All runs and development were done on a Dell XPS 8300...53 Figure 15 . Empirical CDFs of Te124 from Pu239 fast at 0.1 seconds with φ = 20%, as compared to a Normal CDFs with the same mean...concentration parameter to the sum of the 15 concentration parameters. In the case of interest, this is simply the branching fraction mean times

  9. Increased cardiac alpha-myosin heavy chain in left atria and decreased myocardial insulin-like growth factor (Igf-I) expression accompany low heart rate in hibernating grizzly bears.

    Science.gov (United States)

    Barrows, N D; Nelson, O L; Robbins, C T; Rourke, B C

    2011-01-01

    Grizzly bears (Ursus arctos horribilis) tolerate extended periods of extremely low heart rate during hibernation without developing congestive heart failure or cardiac chamber dilation. Left ventricular atrophy and decreased left ventricular compliance have been reported in this species during hibernation. We evaluated the myocardial response to significantly reduced heart rate during hibernation by measuring relative myosin heavy-chain (MyHC) isoform expression and expression of a set of genes important to muscle plasticity and mass regulation in the left atria and left ventricles of active and hibernating bears. We supplemented these data with measurements of systolic and diastolic function via echocardiography in unanesthetized grizzly bears. Atrial strain imaging revealed decreased atrial contractility, decreased expansion/reservoir function (increased atrial stiffness), and decreased passive-filling function (increased ventricular stiffness) in hibernating bears. Relative MyHC-α protein expression increased significantly in the atrium during hibernation. The left ventricle expressed 100% MyHC-β protein in both groups. Insulin-like growth factor (IGF-I) mRNA expression was reduced by ∼50% in both chambers during hibernation, consistent with the ventricular atrophy observed in these bears. Interestingly, mRNA expression of the atrophy-related ubiquitin ligases Muscle Atrophy F-box (MAFBx) and Muscle Ring Finger 1 did not increase, nor did expression of myostatin or hypoxia-inducible factor 1α (HIF-1α). We report atrium-specific decreases of 40% and 50%, respectively, in MAFBx and creatine kinase mRNA expression during hibernation. Decreased creatine kinase expression is consistent with lowered energy requirements and could relate to reduced atrial emptying function during hibernation. Taken together with our hemodynamic assessment, these data suggest a potential downregulation of atrial chamber function during hibernation to prevent fatigue and dilation

  10. Charmless Hadronic Beauty Decays at LHCb

    Science.gov (United States)

    Williams, Timothy

    2017-10-01

    A summary of six LHCb results on the topic of charmless hadronic b-hadron decays is presented. These are comprised of: a search for the decay and updated branching fraction measurements of decays (h=K,π) [1]; the first observation of the decays and strong evidence for the decay [2]; the first observation of the decay [3]; a search for the decay [4]; the first observation of the decay [5] and evidence for CP-violation in decays [6].

  11. Introduction of the human pro. cap alpha. 1(I) collagen gene into pro. cap alpha. 1(I)-deficient Mov-13 mouse cells leads to formation of functional mouse-human hybrid type I collagen

    Energy Technology Data Exchange (ETDEWEB)

    Schnieke, A.; Dziadek, M.; Bateman, J.; Mascara, T.; Harbers, K.; Gelinas, R.; Jaenisch, R.

    1987-02-01

    The Mov-13 mouse strain carries a retroviral insertion in the pro..cap alpha..1(I) collagen gene that prevents transcription of the gene. Cell lines derived from homozygous embryos do not express type I collagen although normal amounts of pro..cap alpha..2 mRNA are synthesized. The authors have introduced genomic clones of either the human or mouse pro..cap alpha..1(I) collagen gene into homozygous cell lines to assess whether the human or mouse pro..cap alpha..1(I) chains can associate with the endogenous mouse pro..cap alpha..2(I) chain to form stable type I collagen. The human gene under control of the simian virus 40 promoter was efficiently transcribed in the transfected cells. Protein analyses revealed that stable heterotrimers consisting of two human ..cap alpha..1 chains and one mouse ..cap alpha..2 chain were formed and that type I collagen was secreted by the transfected cells at normal rates. However, the electrophoretic migration of both ..cap alpha..1(I) and ..cap alpha..2(I) chains in the human-mouse hybrid molecules were retarded, compared to the ..cap alpha..(I) chains in control mouse cells. Inhibition of the posttranslational hydroxylation of lysine and proline resulted in comigration of human and mouse ..cap alpha..1 and ..cap alpha..2 chains, suggesting that increased posttranslational modification caused the altered electrophoretic migration in the human-mouse hybrid molecules. Amino acid sequence differences between the mouse and human ..cap alpha.. chains may interfere with the normal rate of helix formation and increase the degree of posttranslational modifications similar to those observed in patients with lethal perinatal osteogenesis imperfecta. The Mov-13 mouse system should allow the authors to study the effect specific mutations introduced in transfected pro..cap alpha..1(I) genes have on the synthesis, assembly, and function of collagen I.

  12. Systematic study on the competition between α-decay and spontaneous fission of superheavy nuclei

    Science.gov (United States)

    Zhang, Y. L.; Wang, Y. Z.

    2017-10-01

    The competition between α-decay and spontaneous fission (SF) of Z = 112 isotopes are studied. The α-decay half-lives are estimated by the generalized liquid-drop model (GLDM) and several sets of analytic formulas. These formulas include the Royer formula, Viola-Seaborg semiempirical (VSS) formula and universal decay law (UDL). For the SF, its half-lives are calculated by using the Xu, Ren, Karpov and Santhosh formulas. It is shown that the predicted α-decay half-lives by different approaches are more or less identical. However, the SF half-lives are highly sensitive to models. To test the accuracies of different SF formulas, the half-lives of 56 even-even heavy nuclei are calculated by these formulas. By comparing with the experimental data, it is found that the Xu formula is the most accurate one to reproduce the experimental SF half-lives. This allows us to make a systematic prediction on the competition between α-decay and SF of even-even superheavy nuclei (SHN) with Z = 104- 120 by using the Xu formula and the above mentioned models on α-decay. The calculations suggest that 258,260104, 268-276110, 270-280112, 272-286114, 274-294116, 284-302118 and 292-308120 have smaller α-decay half-lives than those of SF. Thus these nuclei can be synthesized and identified via α-decay in the laboratory. In addition, it is observed that N = 162, 178, 184 and 196 may be the submagic or magic numbers. Finally, an extensive study on the possible α-decay chains for Z = 120 isotopes is performed. It is predicted that six sequential α-decay chains can be observed from 292-296120, four α-decay chains from 298120, three α-decay chains from 300,302120, two α-decay chains from 304,306120, and only one α-decay chain from 308120. These nuclei are the most likely candidates to be synthesized experimentally via α-decay in the near future.

  13. Visible neutrino decay at DUNE

    Energy Technology Data Exchange (ETDEWEB)

    Coloma, Pilar [Fermilab; Peres, Orlando G. [ICTP, Trieste

    2017-05-09

    If the heaviest neutrino mass eigenstate is unstable, its decay modes could include lighter neutrino eigenstates. In this case part of the decay products could be visible, as they would interact at neutrino detectors via mixing. At neutrino oscillation experiments, a characteristic signature of such \\emph{visible neutrino decay} would be an apparent excess of events at low energies. We focus on a simple phenomenological model in which the heaviest neutrino decays as $\

  14. JNDC FP decay data file

    International Nuclear Information System (INIS)

    Yamamoto, Tohru; Akiyama, Masatsugu

    1981-02-01

    The decay data file for fission product nuclides (FP DECAY DATA FILE) has been prepared for summation calculation of the decay heat of fission products. The average energies released in β- and γ-transitions have been calculated with computer code PROFP. The calculated results and necessary information have been arranged in tabular form together with the estimated results for 470 nuclides of which decay data are not available experimentally. (author)

  15. Polyneutron Chain Reactions

    International Nuclear Information System (INIS)

    John C. Fisher

    2000-01-01

    Although helium atoms do not form molecules, a sufficiently large number will bind into a stable liquid droplet. A comparable situation is expected for neutrons, with a sufficiently large number binding into a stable droplet of neutron matter. Such polyneutron droplets can be viewed as isotopes of an element with nuclear charge Z=0, tentatively denoted neutrium, symbol Nt. Because of the relatively weak binding of neutrons compared with that of a mix of neutrons and protons, the minimum number of neutrons required for stability of a droplet is fairly large. Early estimates of ∼60 may be reduced to a dozen or so by the BCS pairing interaction. The Nt entries with N≥12 are new to the table of isotopes. Because all of them are beta-unstable, none is expected to persist as a free particle. Yet, some may occasionally be produced by means to be described below, and it is of interest to examine their decay chains and their interactions with charged nuclei to ascertain how their presence might be revealed. Although these reactions are interesting, they cannot be taken seriously without identifying a source for the initial Nt isotope that begins the chain. Here, we consider possible interactions between 16 O and A Nt. Although there is no strong interaction between them, we can expect a very weak residual attraction that can form a loosely bound 16 O A Nt nuclear molecule. This is not a compound nucleus in the usual sense because, considered as fluids, the 16 O and A Nt droplets are immiscible. For a droplet with fewer than about 60 neutrons, beta decay of A Nt is prevented by the buildup of Coulomb energy associated with transforming A Nt into A H in close proximity to 16 O. Thus, it is possible that 16 O A Nt molecules can persist indefinitely and that a few of them may be present in ordinary water as supermassive oxygen nuclei. Because the binding of these molecules is weak, the A Nt component can tunnel to an adjacent nucleus, and if the adjacent nucleus is 18 O, a

  16. Lyman Alpha Control

    CERN Document Server

    Nielsen, Daniel Stefaniak

    2015-01-01

    This document gives an overview of how to operate the Lyman Alpha Control application written in LabVIEW along with things to watch out for. Overview of the LabVIEW code itself as well as the physical wiring of and connections from/to the NI PCI-6229 DAQ box is also included. The Lyman Alpha Control application is the interface between the ALPHA sequencer and the HighFinesse Wavelength Meter as well as the Lyman Alpha laser setup. The application measures the wavelength of the output light from the Lyman Alpha cavity through the Wavelength Meter. The application can use the Wavelength Meter’s PID capabilities to stabilize the Lyman Alpha laser output as well as switch between up to three frequencies.

  17. New ALPHA-2 magnet

    CERN Multimedia

    Anaïs Schaeffer

    2012-01-01

    On 21 June, members of the ALPHA collaboration celebrated the handover of the first solenoid designed for the ALPHA-2 experiment. The magnet has since been successfully installed and is working well.   Khalid Mansoor, Sumera Yamin and Jeffrey Hangst in front of the new ALPHA-2 solenoid. “This was the first of three identical solenoids that will be installed between now and September, as the rest of the ALPHA-2 device is installed and commissioned,” explains ALPHA spokesperson Jeffrey Hangst. “These magnets are designed to allow us to transfer particles - antiprotons, electrons and positrons - between various parts of the new ALPHA-2 device by controlling the transverse size of the particle bunch that is being transferred.” Sumera Yamin and Khalid Mansoor, two Pakistani scientists from the National Centre for Physics in Islamabad, came to CERN in February specifically to design and manufacture these magnets. “We had the chance to work on act...

  18. Searching for exotic tau decays

    CERN Document Server

    Alemany, R; González-Garciá, M Concepción; Valle, José W F

    1993-01-01

    We discuss the potential of $\\tau$-charm and B factories for the search of new physics through the study of rare $\\tau$ decays. We consider decays that involve the violation of lepton flavour conservation. Such decays bear a close relationship to the physics of neutrino mass and the properties of the lepton sector of the electroweak theory.

  19. Decay of 57Ni

    International Nuclear Information System (INIS)

    Santos Scardino, A.M. dos.

    1987-01-01

    The decay of 57 Ni to 57 Co was studied by gamma ray spectroscopy using both singles and coincidence spectra. The sources were obtained with the 58 Ni (Y,n) 57 Ni reaction. Natural metallic nickel was irradiated in the bremsstrahluhng beam of the linear accelerator of the Instituto de Fisica da Universidade de Sao Paulo with 30 MeV electrons. The singles espectra were taken with 104 cc HPGe detector and the coincidences espectra with 27 and 53cc Ge(Li) and 104 cc. HPGe detectors. The energies of transitions that follow the 57 Ni decay were measured using 56 Co as standard (which was obtained by (Y,np) reaction in 58 Ni) and taking into account the cascade cross-over relations. (author) [pt

  20. Electroweak penguin B decays

    CERN Document Server

    Nikodem, Thomas

    2016-01-01

    Flavour Changing Neutral Currents (FCNC) are sensitive probes for physics beyond the Standard Model (SM), so-called New Physics. An example of a FCNC is the $b \\to s$ quark transition described by the electroweak penguin Feynman diagram shown in Figure 1. In the SM such FCNC are only allowed with a loop structure (as e:g: shown in the figure) and not by tree level processes. In the loops heavy particles appear virtually and do not need to be on shell. Therefore also not yet discovered heavy particles with up to a mass $\\mathcal{O}$(TeV) could virtually contribute significantly to observables. Several recent measurements of electroweak penguin B decays exhibit interesting tensions with SM predictions, most prominently in the angular observable $P'_5$ 5 of the decay $B^0 \\to K^{*0} \\mu^+ \\mu^1$[1], which triggered a lot of discussion in the theory community [2]-[14].

  1. Some neutrino decays

    International Nuclear Information System (INIS)

    Levy, J.M.

    1984-01-01

    Massive neutrinos mixing with weak interaction eigenstates are expected to decay into various channels depending on their masses and their mixing pattern. The author reviews some of these decay modes in the simpliest possible frame (νsub(H) → e - e + νsub(e), νsub(n) → γνsub(e), νsub(n) → γγνsub(e) and considers only the addition of right handed neutrino fields to the spectrum of the standard Glashow-Salam-Weinberg theory of weak interactions, thereby allowing for the existence of Dirac masses generated through the coupling of these fields and their left handed mates with the usual Higgs doublet and its charge conjugate, as is the case for quarks

  2. An application program for fission product decay heat calculations

    International Nuclear Information System (INIS)

    Pham, Ngoc Son; Katakura, Jun-ichi

    2007-10-01

    The precise knowledge of decay heat is one of the most important factors in safety design and operation of nuclear power facilities. Furthermore, decay heat data also play an important role in design of fuel discharges, fuel storage and transport flasks, and in spent fuel management and processing. In this study, a new application program, called DHP (Decay Heat Power program), has been developed for exact decay heat summation calculations, uncertainty analysis, and for determination of the individual contribution of each fission product. The analytical methods were applied in the program without any simplification or approximation, in which all of linear and non-linear decay chains, and 12 decay modes, including ground state and meta-stable states, are automatically identified, and processed by using a decay data library and a fission yield data file, both in ENDF/B-VI format. The window interface of the program is designed with optional properties which is very easy for users to run the code. (author)

  3. Alpha Shapes and Proteins

    DEFF Research Database (Denmark)

    Winter, Pawel; Sterner, Henrik; Sterner, Peter

    2009-01-01

    We provide a unified description of (weighted) alpha shapes, beta shapes and the corresponding simplicialcomplexes. We discuss their applicability to various protein-related problems. We also discuss filtrations of alpha shapes and touch upon related persistence issues.We claim that the full...... potential of alpha-shapes and related geometrical constructs in protein-related problems yet remains to be realized and verified. We suggest parallel algorithms for (weighted) alpha shapes, and we argue that future use of filtrations and kinetic variants for larger proteins will need such implementation....

  4. Determination of alpha radionuclides in fish

    International Nuclear Information System (INIS)

    Pernicka, L.; Matel, L.; Rosskopfova, O.

    2001-01-01

    In atmospheric water, external water and undercurrent the occurrence of radionuclides is usual. It is an important factor of quality of the environment. Plants ingest radionuclides from water and with they everyone. And it arises radioactivity infest food-chain. Radiotoxicity of this radionuclides is very deer sometimes. The sensitive radiochemical procedures for their determination are necessarily important. The poster presents the combined procedure used at our laboratory for determination of alpha radionuclides in biological samples. (authors)

  5. Decay of 83Sr

    International Nuclear Information System (INIS)

    Yu Xiaohan; Shi Shuanghui; Gu Jiahui

    1997-01-01

    The decay of 83 Sr was reinvestigated using γ singles and γ-γ-t coincidence measurement. A new level scheme of Rb, which contains 41 excited levels and about 180 transitions, is constructed. 19 new levels were added to the old level scheme and 8 formerly adopted levels were denied. A new data set of branching ratio, log(ft) value and spin parity was obtained

  6. Biosynthesis of Tcr-alpha, beta and Tcr-gamma, delta/CD3 complexes

    DEFF Research Database (Denmark)

    Bauguil-Caspar, S; Arnaud, J; Kuhlmann, J

    1993-01-01

    Jurkat J76 clone, LYON L12.37 clone and L12.37 cells transfected with J76-alpha cDNA or J76 Tcr-alpha mutated cDNA (J79) were analysed for membrane expression of Tcr/CD3 complex using WT31 mAb (Tcr-alpha, beta) or Tcr-delta 1 mAb (Tcr-gamma, delta): LYON cells express V beta 9 bearing Tcr-beta...... chains. J76 Tcr-alpha cDNA transfected LYON cells have intracellular Tcr-gamma, delta chains and J79 Tcr-alpha cDNA transfected LYON cells have intracellular Tcr-alpha (M), beta chains....

  7. Radioactive decay data tables

    Energy Technology Data Exchange (ETDEWEB)

    Kocher, D.C.

    1981-01-01

    The estimation of radiation dose to man from either external or internal exposure to radionuclides requires a knowledge of the energies and intensities of the atomic and nuclear radiations emitted during the radioactive decay process. The availability of evaluated decay data for the large number of radionuclides of interest is thus of fundamental importance for radiation dosimetry. This handbook contains a compilation of decay data for approximately 500 radionuclides. These data constitute an evaluated data file constructed for use in the radiological assessment activities of the Technology Assessments Section of the Health and Safety Research Division at Oak Ridge National Laboratory. The radionuclides selected for this handbook include those occurring naturally in the environment, those of potential importance in routine or accidental releases from the nuclear fuel cycle, those of current interest in nuclear medicine and fusion reactor technology, and some of those of interest to Committee 2 of the International Commission on Radiological Protection for the estimation of annual limits on intake via inhalation and ingestion for occupationally exposed individuals.

  8. MULTIFLUID MAGNETOHYDRODYNAMIC TURBULENT DECAY

    International Nuclear Information System (INIS)

    Downes, T. P.; O'Sullivan, S.

    2011-01-01

    It is generally believed that turbulence has a significant impact on the dynamics and evolution of molecular clouds and the star formation that occurs within them. Non-ideal magnetohydrodynamic (MHD) effects are known to influence the nature of this turbulence. We present the results of a suite of 512 3 resolution simulations of the decay of initially super-Alfvenic and supersonic fully multifluid MHD turbulence. We find that ambipolar diffusion increases the rate of decay of the turbulence while the Hall effect has virtually no impact. The decay of the kinetic energy can be fitted as a power law in time and the exponent is found to be -1.34 for fully multifluid MHD turbulence. The power spectra of density, velocity, and magnetic field are all steepened significantly by the inclusion of non-ideal terms. The dominant reason for this steepening is ambipolar diffusion with the Hall effect again playing a minimal role except at short length scales where it creates extra structure in the magnetic field. Interestingly we find that, at least at these resolutions, the majority of the physics of multifluid turbulence can be captured by simply introducing fixed (in time and space) resistive terms into the induction equation without the need for a full multifluid MHD treatment. The velocity dispersion is also examined and, in common with previously published results, it is found not to be power law in nature.

  9. Targeted Alpha Therapy: From Alpha to Omega

    International Nuclear Information System (INIS)

    Allen, Barry J; Clarke, Raymond; Huang Chenyu

    2013-01-01

    This review covers the broad spectrum of Targeted Alpha Therapy (TAT) research in Australia; from in vitro and in vivo studies to clinical trials. The principle of tumour anti-vascular alpha therapy (TAVAT) is discussed in terms of its validation by Monte Carlo calculations of vascular models and the potential role of biological dosimetry is examined. Summmary of this review is as follows: 1. The essence of TAT 2. Therapeutic objectives 3. TAVAT and Monte Carlo microdosimetry 4. Biological dosimetry 5. Preclinical studies 6. Clinical trials 7. What next? 8. Obstacles. (author)

  10. Charmless b decays at CDF

    Energy Technology Data Exchange (ETDEWEB)

    Donega, Mauro; /Geneva U.

    2005-07-01

    The authors report on the charmless B decays measurements performed on 180 pb{sup -1} of data collected with the CDF II detector at the Fermilab Tevatron collider. This paper describes: the first observation of the decay mode B{sub s} {yields} K{sup +}K{sup -} and the measurement of the direct Cp asymmetry in the ({bar B}){sub d} {yields} K{sup {+-}}{pi}{sup {-+}} decay; the first evidence of the decay mode B{sub s} {yields} {phi}{phi} and the branching ratio and Cp asymmetry for the B{sup {+-}} {yields} {phi}K{sup {+-}} decay.

  11. The ALPHA project: a progress report

    International Nuclear Information System (INIS)

    Yadigaroglu, G.; Cachard, F. de; Coddington, P.; Dreier, J.; Smith, B.; Guentay, S.; Varadi, G.

    1995-01-01

    A review of the ALPHA project is presented, including a summary of progress and current status. The project comprises the experimental and analytical investigation of the long-term decay heat removal phenomena from the containment of the next generation of 'passive' Advanced Light Water Reactors. The effects of aerosols that may result from hypothetical severe accidents are also considered. The construction of the major ALPHA experimental facilities, PANDA, LINX-2 and AIDA, has been completed and all facilities are now in their commissioning phases. Scaling studies have guided the design of the experimental facilities. Several small-scale experiments and studies have already produced valuable results which can be used to direct the experimental work, as well as the design of the passive ALWRs. (author) 7 figs., 23 refs

  12. Transchromosomally derived Ig heavy chains

    Energy Technology Data Exchange (ETDEWEB)

    Knight, K.L.; Kingzette, M.; Crane, M.A. [Loyola Univ. Chicago, Maywood, IL (United States)] [and others

    1995-07-15

    During an immune response, activated B cells undergo isotype switching and begin to express isotypes other than IgM and IgD. Isotype switching occurs when downstream C{gamma}, C{alpha}, or C{epsilon} genes are rearranged into the S{mu} chromosomal region, resulting in the deletion of the region in between. These rearrangements usually occur in cis, i.e., intrachromosomally. In previous studies, we analyzed allotypic specificities of rabbit secretory IgA and identified a substantial number of IgA heavy chains with V{sub h} and C{alpha} allotypes that were encoded by V{sub h} and C{alpha} genes in trans. In those studies, however, we could not determine whether the trans association of V{sub H} and C{alpha} occurred during VDJ gene rearrangement or during isotype switching. Here, we cloned rabbit cDNA which encodes these trans IgA heavy chains and determined the chromosomal origin of the V{sub H}, J{sub H}, and C{alpha} regions. To determine whether the trans association occurred during VDJ gene rearrangement, we analyzed the nucleotide polymorphism of the J{sub H} region and the V{sub H} allotype encoded by the cDNA. We found that the V{sub H} and J{sub H} genes used in the VDJ gene rearrangements were from the same chromosome, indicating that the V{sub H}, D, and J{sub H} gene rearrangements occurred in cis. Furthermore, we analyzed the DNA polymorphisms of J{sub H} and C{alpha} and showed that the VDJ and C{alpha} genes encoding the trans IgA molecules were derived from different parental chromosomes. We suggest that the trans association occurred during isotype switching. This study shows that V{sub H} and C{sub H} can associate transchromosomally as part of a normal immune response. 34 refs., 5 figs.

  13. Further limit on 3α decay of Hoyle state

    Directory of Open Access Journals (Sweden)

    Rana T. K.

    2014-03-01

    Full Text Available The quantitative contributions of various direct three alpha decay mechanisms in the decay of the famous Hoyle state, the 02+ resonant excited state of 12C at excitation energy of 7.65 MeV, has been estimated using 60 MeV α inelastic scattering on 12C target in complete kinematical measurement. Simultaneous optimisation of three different distributions (the relative energy of 8Be like pairs, the root mean square energy deviation and the radial projection of symmetric Dalitz plot derived from the experimental data with those generated from the Monte Carlo simulated event sets, have been done to arrive at a consistent estimation of the contributions of various direct decay modes.

  14. Column: Factors Affecting Data Decay

    Directory of Open Access Journals (Sweden)

    Kevin Fairbanks

    2012-06-01

    Full Text Available In nuclear physics, the phrase decay rate is used to denote the rate that atoms and other particles spontaneously decompose. Uranium-235 famously decays into a variety of daughter isotopes including Thorium and Neptunium, which themselves decay to others. Decay rates are widely observed and wildly different depending on many factors, both internal and external. U-235 has a half-life of 703,800,000 years, for example, while free neutrons have a half-life of 611 seconds and neutrons in an atomic nucleus are stable.We posit that data in computer systems also experiences some kind of statistical decay process and thus also has a discernible decay rate. Like atomic decay, data decay fluctuates wildly. But unlike atomic decay, data decay rates are the result of so many different interplaying processes that we currently do not understand them well enough to come up with quantifiable numbers. Nevertheless, we believe that it is useful to discuss some of the factors that impact the data decay rate, for these factors frequently determine whether useful data about a subject can be recovered by forensic investigation.(see PDF for full column

  15. Rare B decays at LHCb

    CERN Document Server

    Puig Navarro, Albert

    2017-01-01

    Rare decays are flavour changing neutral current processes that allow sensitive searches for phenomena beyond the Standard Model (SM). In the SM, rare decays are loop-suppressed and new particles in SM extensions can give significant contributions. The very rare decay $B^0_s\\to\\mu^+\\mu^-$ in addition helicity suppressed and constitutes a powerful probe for new (pseudo) scalar particles. Of particular interest are furthermore tests of lepton universality in rare $b\\to s\\ell^+\\ell^-$ decays. The LHCb experiment is designed for the study of b-hadron decays and ideally suited for the analysis of rare decays due to its high trigger efficiency, as well as excellent tracking and particle identification performance. Recent results from the LHCb experiment in the area of rare decays are presented, including tests of lepton universality and searches for lepton flavour violation.

  16. Alpha1-antitrypsin deficiency

    DEFF Research Database (Denmark)

    Stolk, Jan; Seersholm, Niels; Kalsheker, Noor

    2006-01-01

    The Alpha One International Registry (AIR), a multinational research program focused on alpha1-antitrypsin (AAT) deficiency, was formed in response to a World Health Organization recommendation. Each of the nearly 20 participating countries maintains a national registry of patients with AAT defic...... epidemiology, inflammatory and signalling processes, therapeutic advances, and lung imaging techniques....

  17. Alpha clustering in nuclei

    International Nuclear Information System (INIS)

    Hodgson, P.E.

    1990-01-01

    The effects of nucleon clustering in nuclei are described, with reference to both nuclear structure and nuclear reactions, and the advantages of using the cluster formalism to describe a range of phenomena are discussed. It is shown that bound and scattering alpha-particle states can be described in a unified way using an energy-dependent alpha-nucleus potential. (author)

  18. Characteristic of aromatic amino acid substitution at alpha 96 of hemoglobin.

    Science.gov (United States)

    Choi, Jong-Whan; Lee, Jong Hyuk; Lee, Kwang Ho; Lee, Hyean-Woo; Sohn, Joon Hyung; Yoon, Joon Ho; Yeh, Byung-Il; Park, Seung Kyu; Lee, Kyu Jae; Kim, Hyun-Won

    2005-01-31

    Replacement of valine by tryptophan or tyrosine at position alpha96 of the alpha chain (alpha96Val), located in the alpha(1)beta(2) subunit interface of hemoglobin leads to low oxygen affinity hemoglobin, and has been suggested to be due to the extra stability introduced by an aromatic amino acid at the alpha96 position. The characteristic of aromatic amino acid substitution at the alpha96 of hemoglobin has been further investigated by producing double mutant r Hb (alpha42Tyr --> Phe, alpha96Val --> Trp). r Hb (alpha42Tyr --> Phe) is known to exhibit almost no cooperativity in binding oxygen, and possesses high oxygen affinity due to the disruption of the hydrogen bond between alpha42Tyr and beta99Asp in thealpha(1)beta(2) subunit interface of deoxy Hb A. The second mutation, alpha96Val -->Trp, may compensate the functional defects of r Hb (alpha42Tyr --> Phe), if the stability due to the introduction of trypophan at the alpha 96 position is strong enough to overcome the defect of r Hb (alpha42Tyr --> Phe). Double mutant r Hb (alpha42Tyr --> Phe, alpha96Val --> Trp) exhibited almost no cooperativity in binding oxygen and possessed high oxygen affinity, similarly to that of r Hb (alpha42Tyr --> Phe). (1)H NMR spectroscopic data of r Hb (alpha42Tyr --> Phe, alpha96Val --> Trp) also showed a very unstable deoxy-quaternary structure. The present investigation has demonstrated that the presence of the crucible hydrogen bond between alpha 42Tyr and beta 99Asp is essential for the novel oxygen binding properties of deoxy Hb (alpha96Val --> Trp) .

  19. Efficient alpha-(alkylthio)alkyl-type radical formation in (*)OH-induced oxidation of alpha-(methylthio)acetamide.

    Science.gov (United States)

    Wisniowski, Pawel B; Hug, Gordon L; Pogocki, Dariusz; Bobrowski, Krzysztof

    2010-01-14

    Pulse radiolysis with UV-vis/ESR detection and steady-state gamma-radiolysis, combined with chromatographic techniques, were used to investigate the detailed mechanism of the (*)OH-induced oxidation of alpha-(methylthio)acetamide (alpha-MTA) in aqueous solution. The main pathway involves the formation of hydroxysulfuranyl radicals alpha-MTA-(>S(*)-OH) and alpha-(alkylthio)alkyl radicals H(3)C-S-(*)CH-C( horizontal lineO)-NH(2) (lambda(max) effect of both substituents in terms of the captodative effect. At low pH, alpha-MTA-(>S(*)-OH) radicals undergo efficient conversion to intermolecularly three-electron-bonded dimeric radical cations of alpha-MTA-(>S thereforeSS(*)-OH) radicals decompose via the elimination of water, formed through intramolecular hydrogen (attached to the nitrogen atom) transfer to the hydroxysulfuranyl moiety within a six-membered structure. This process leads to the formation of the imine radical H(3)C-S-CH(2)-C( horizontal lineO)(*)NH, which subsequently decays in three independent channels. The first decay channel begins with a beta-scission followed by hydrolysis and a subsequent Hofmann rearrangement. One of the end products of this first decay channel is CO(2), which was detected. The second decay channel involves an intramolecular hydrogen transfer from the deltaC carbon atom to the radical imine site producing the alpha-(alkylthio)alkyl radical H(2)C(*)-S-CH(2)-C( horizontal lineO)-NH(2). In the third decay channel there is a 1,3-hydrogen shift in the imine radical which forms the radical H(3)C-S-(*)CH-C( horizontal lineO)-NH(2). The presence of the amide group induces more complex radical chemistry that leads unexpectedly to the degradation of the CH(3)SCH(2)CONH(2) molecule into gaseous products, CO(2) and NH(3). These features of the mechanism of the (*)OH-induced oxidation of alpha-MTA are quite different from those seen in other organic sulfides in neutral solutions.

  20. Radon Daughters Background Reduction in Alpha Particles Counting System

    International Nuclear Information System (INIS)

    Dadon, S. S.; Pelled, O.; Orion, I.

    2014-01-01

    The ABPC method is using a serially occurring events of the beta decay of the 214Bi fallow by alpha decay of the 214Po that take place almost simultaneously to detect the Pseudo Coincidence Event (PCE) from the RDP, and to subtract them from the gross alpha counts. 267 This work showed that it is possible to improve the efficiency of RDP background reduction, including subtracting the 218Po contribution by using the ABPC method based on a single solid state silicon PIPS detector. False counts percentage obtained at the output of the PCE circuit were smaller than 0.1%. The results show that the PCE circuit was not influenced by non RDP alpha emitters. The PCE system did not reduce the non PCE of the 218Po. After 20 minutes the 218Po was strongly decayed, and its contribution became negligible. In order to overcome this disadvantage, a mathematical matching calculations for the 214Po and the 218Po decay equations were employed, and a constant ratio of the APo214(0) / APo218(0) was obtained. This ratio can be used to estimate the count rate of the 218Po at the first 20 minutes, and to subtract it from the total count rate in order to obtain correct RDP reduction

  1. DECSERVIS-2: A tool for natural decay series mass flow simulation

    International Nuclear Information System (INIS)

    Azzam, Saad; Suksi, Juhani; Ammann, Michael

    2009-01-01

    After the publication of 'DECSERVIS: a tool for radioactive decay series visualisation' we have further developed our DECSERVIS software. With the new tool DECSERVIS-2 one can simulate radioactive decay chains in open systems, i.e. when the concentrations of nuclides change also due to mass flows. Decay chains can be simulated under continuous and successive nuclide mass flow events into and out from the system and in freely determined time intervals. Simulation output for the entire decay chain (nuclide activity, mass, number of nuclides, nuclide ratios) can be presented as a function of time with various graphical presentations such as solid curve and column diagrams or animation. In this paper we introduce DECSERVIS-2 and demonstrate its use with simulation examples. DECSERVIS-2 is easy to use and has been designed with an eye on the demands of teaching.

  2. Decay scheme of the U{sup 2}35; Esquema de desintegracion del U-235

    Energy Technology Data Exchange (ETDEWEB)

    Gaeta, R.

    1965-07-01

    A study of the Th{sup 2}31 excited levels from the alpha decay of the U{sup 2}35, is carried out. The alpha particle spectrum was measured by means of a semiconductor counter spectrometer with an effective resolution of 18 keV. Nineteen new lines were identified. The gamma-ray spectrum was measured with thin samples of U{sup 2}35, free from decay products, and in such geometrical conditions, that most of the interference effects were eliminated. The gamma-gamma coincidence spectra have made easier a better knowledge of the transition between the several levels. (Author) 110 refs.

  3. Measurement of {alpha}{sub s} with radiative hadronic events

    Energy Technology Data Exchange (ETDEWEB)

    Abbiendi, G.; Braibant, S.; Capiluppi, P.; Ciocca, C.; Cuffiani, M.; Dallavalle, M.; Fabbri, F.; Giacomelli, G.; Giacomelli, P.; Marcellini, S.; Michelini, A.; Rossi, A.M. [Dipartimento di Fisica dell' Universita di Bologna and INFN, Bologna (Italy); Ainsley, C.; Batley, R.J.; Carter, J.R.; Hill, J.C.; Thomson, M.A.; Ward, C.P.; Ward, D.R. [Cavendish Laboratory, Cambridge (United Kingdom); Aakesson, P.F.; Burckhart, H.J.; De Roeck, A.; Ferrari, P.; Frey, A.; Gruwe, M.; Hauschild, M.; Hawkings, R.; Meijers, F.; Oh, A.; Plane, D.E.; Rembser, C.; Scharff-Hansen, P.; Schroeder, M.; Smith, A.M.; Wells, P.S.; Wengler, T. [CERN, European Organisation for Nuclear Research, Geneva 23 (Switzerland); Alexander, G.; Bella, G.; Etzion, E.; Grunhaus, J.; Tsur, E. [Tel Aviv Univ., Department of Physics and Astronomy, Tel Aviv (Israel); Anagnostou, G.; Bell, P.J.; Charlton, D.G.; Hawkes, C.M.; Jovanovic, P.; O' Neale, S.W.; Turner-Watson, M.F.; Watkins, P.M.; Watson, A.T.; Watson, N.K.; Wilson, J.A. [Univ. of Birmingham, School of Physics and Astronomy, Birmingham (United Kingdom); Anderson, K.J.; Gupta, A.; Merritt, F.S.; Oreglia, M.J.; Pilcher, J.E.; Teuscher, R. [Univ. of Chicago, Enrico Fermi Institute and Department of Physics, Chicago, IL (United States); Asai, S.; Ishii, K.; Kawagoe, K.; Kawamoto, T.; Kobayashi, T.; Komamiya, S.; Mashimo, T.; Mihara, S.; Mori, T.; Nanjo, H.; Orito, S.; Saeki, T.; Toya, D.; Ueda, I.; Yamashita, S. [Univ. of Tokyo, International Centre for Elementary Particle Physics and Department of Physics, Tokyo (Japan)]|[Kobe Univ., Kobe (Japan); Axen, D.; McKenna, J. [Univ. of British Columbia, Department of Physics, Vancouver, BC (Canada); Bailey, I.; Karlen, D.; Keeler, R.K.; McPherson, R.A.; Roney, J.M.; Sobie, R. [Univ. of Victoria, Department of Physics, P.O. Box 3055, Victoria, BC (Canada); Barberio, E. [CERN, European Organisation for Nuclear Research, Geneva 23 (Switzerland)]|[Univ. of Melbourne, Victoria (Australia)] [and others

    2008-01-15

    Hadronic final states with a hard isolated photon are studied using data taken at centre-of-mass energies around the mass of the Z boson with the OPAL detector at LEP. The strong coupling {alpha}{sub s} is extracted by comparing data and QCD predictions for event shape observables at average reduced centre-of-mass energies ranging from 24 GeV to 78 GeV, and the energy dependence of {alpha}{sub s} is studied. Our results are consistent with the running of {alpha}{sub s} as predicted by QCD and show that within the uncertainties of our analysis event shapes in hadronic Z decays with hard and isolated photon radiation can be described by QCD at reduced centre-of-mass energies. Combining all values from different event shape observables and energies gives {alpha}{sub s}(M{sub Z})=0.1182{+-}0.0015(stat.){+-}0.0101(syst.). (orig.)

  4. Method and apparatus for indicating the radioactive decay products of radium in an environment

    International Nuclear Information System (INIS)

    Shreve, J.D. Jr.; Trowsdale, L.S.; Hill, A.

    1976-01-01

    An improved method and apparatus for providing an indication of the radiation activity of the radioactive decay products of radium in an environment wherein the alpha particle activity and the beta particle activity at a test site are detected and the detected alpha particle and the beta particle activities provide the indication of the radiation activity of radon and the decay products of radon at the test site. The background radiation activity at the test site is detected, and the detected alpha particle and the beta particle activities less the detected background radiation activity provide the indication of the radiation activity of radon and the decay products of radon. The sum of the detected alpha particle and beta particle activities provides an indication of the working level (WL); the difference between the detected alpha particle and the beta particle activities provides an indication of the radon concentration at the test site and the equivalent ingrowth time of the radon decay products (radon daughters) from the earlier existence of the radon as a gas; and the detected background radiation activity provides an indication of the penetrating radiation hazard at the test site. 40 claims, 8 figures

  5. Method and apparatus for indicating the radioactive decay products of radium in an environment

    Energy Technology Data Exchange (ETDEWEB)

    Shreve, J.D. Jr.; Trowsdale, L.S.; Hill, A.

    1976-10-26

    An improved method and apparatus for providing an indication of the radiation activity of the radioactive decay products of radium in an environment wherein the alpha particle activity and the beta particle activity at a test site are detected and the detected alpha particle and the beta particle activities provide the indication of the radiation activity of radon and the decay products of radon at the test site. The background radiation activity at the test site is detected, and the detected alpha particle and the beta particle activities less the detected background radiation activity provide the indication of the radiation activity of radon and the decay products of radon. The sum of the detected alpha particle and beta particle activities provides an indication of the working level (WL); the difference between the detected alpha particle and the beta particle activities provides an indication of the radon concentration at the test site and the equivalent ingrowth time of the radon decay products (radon daughters) from the earlier existence of the radon as a gas; and the detected background radiation activity provides an indication of the penetrating radiation hazard at the test site. 40 claims, 8 figures.

  6. Decay of Hoyle state

    Indian Academy of Sciences (India)

    2014-11-02

    Nov 2, 2014 ... Hoyle state also, there is discrepancy between various model predictions [18]; whereas. FMD predicts a compact triangle shape and LEFT predicts a bent arm chain structure,. BEC model predicts the Hoyle state to be spherically symmetric. Moreover, the r.m.s. radii of the Hoyle state, predicted by the above ...

  7. Genetics Home Reference: alpha thalassemia

    Science.gov (United States)

    ... Facebook Twitter Home Health Conditions Alpha thalassemia Alpha thalassemia Printable PDF Open All Close All Enable Javascript to view the expand/collapse boxes. Description Alpha thalassemia is a blood disorder that reduces the production ...

  8. Humanitarian relief supply chain

    Indian Academy of Sciences (India)

    This paper models a humanitarian relief chain that includes a relief goods supply chain and an evacuation chain in case of a natural disaster. Optimum network flow is studied for both the chains by considering three conflicting objectives, namely demand satisfaction in relief chain, demand satisfaction in evacuation chain ...

  9. New semi-empirical formula for α -decay half-lives of the heavy and superheavy nuclei

    Science.gov (United States)

    Manjunatha, H. C.; Sridhar, K. N.

    2017-07-01

    We have succesfully formulated the semi-empirical formula for α -decay half-lives of heavy and superheavy nuclei for different isotopes of the wide atomic-number range 94 Royer10, VS2, UNIV2, SemFIS2, WKB. Sahu16, Densov, VSS and Royer formula. This formula is exclusively for heavy and superheavy nuclei. α -decay is one of the dominant decay mode of superheavy nucleus. By identifying the α -decay mode superheavy nuclei can be detected. This formula helps in predicting the α -decay chains of superheavy nuclei.

  10. Hunting for the alpha: $B\\to \\rho\\rho$, $B \\to \\pi\\pi$, $B \\to\\pi\\rho$

    OpenAIRE

    Ovanesyan, G. G.; Vysotsky, M. I.

    2005-01-01

    The hypothesis of the smallness of penguin contribution to charmless strangeless $B_d (\\bar B_d)$ decays allows to determine with high accuracy the value of angle $\\alpha$ from the currently available $B \\to \\rho\\rho$, $B \\to \\pi\\pi$ and $B\\to \\rho\\pi$ decay data.

  11. Astrophysical rate of O-15(alpha,gamma)Ne-19 via the (p, t) reaction in inverse kinematics

    NARCIS (Netherlands)

    Davids, B; van den Berg, AM; Dendooven, P; Fleurot, F; Hunyadi, M; de Huu, MA; Siemssen, RH; Wilschut, HW; Wortche, HJ; Hernanz, M; Jose, J; Rehm, KE; Wuosmaa, AH; Segel, RE

    A recoil coincidence technique has been applied to measure the alpha-decay branching ratios of near-threshold states in Ne-19. Populating these states using the (p,t) reaction in inverse kinematics, we detected the recoils and their decay products with 100% geometric efficiency using a magnetic

  12. Rare beauty and charm decays

    Science.gov (United States)

    Blake, T.; LHCb Collaboration

    2017-07-01

    Rare beauty and charm decays can provide powerful probes of physics beyond the Standard Model. These proceedings summarise the latest measurements of rare beauty and charm decays from the LHCb experiment at the end of Run 1 of the LHC. Whilst the majority of the measurements are consistent with SM predictions, small differences are seen in the rate and angular distribution of ℓ- decay processes.

  13. Weak decays of heavy quarks

    International Nuclear Information System (INIS)

    Gaillard, M.K.

    1978-08-01

    The properties that may help to identify the two additional quark flavors that are expected to be discovered. These properties are lifetime, branching ratios, selection rules, and lepton decay spectra. It is also noted that CP violation may manifest itself more strongly in heavy particle decays than elsewhere providing a new probe of its origin. The theoretical progress in the understanding of nonleptonic transitions among lighter quarks, nonleptonic K and hyperon decay amplitudes, omega minus and charmed particle decay predictions, and lastly the Kobayashi--Maskawa model for the weak coupling of heavy quarks together with the details of its implications for topology and bottomology are treated. 48 references

  14. Charm meson decays at CESR

    International Nuclear Information System (INIS)

    Yamamoto, H.

    1994-01-01

    The author discusses a number of different topics. First is the question of where CESR will be in the year 2000, in terms of luminosity and its detector, and the impact of this on charm physics. Also what has been learned of semileptonic decays of D 0 , D + , D s , and Cabbibo-favored/suppressed decays. Studies of hadronic decays, Cabbibo-favored/suppressed, rare decays, mixing, and CP invariance. What role can a Tau Charm Factory play in this type of physics, and what can it tell us beyond what we can reach at present

  15. Updated decay and photon libraries for the ORIGEN code

    Energy Technology Data Exchange (ETDEWEB)

    Croff, A. G.; Haese, R. L.; Gove, N. B.

    1979-02-01

    Previously existing decay and photon libraries for the ORIGEN computer code were updated by utilizing a variety of sources. Information obtained form the Evaluated Nuclear Structure Data File (ENSDF) at ORNL was used to revise the half-lives, branching ratios, and recoverable heat values for 427 isotopes. Fifty-seven delayed-neutron precursors were included, on the basis of information in ENDF/B-IV. The natural abundances and the Radionuclide Concentration Guide values were updated for all isotopes. The decay heat values predicted by use of the new decay library were found to compare favorably with those given in the proposed 1978 ANS Standard 5.1 (draft ANSI/ANS-5.1, ''Proposed American National Standard Decay Heat Power in Light Water Reactors''). A new photon library was also generated for 427 isotopes, based principally on data presented in ENSDF. The photon library includes decay gamma and x rays, conversion photons, (..cap alpha..,n) gamma rays, prompt and fission product gamma rays from spontaneous fission, and bremsstrahlung. Both of the revised libraries are listed. 1 figure, 9 tables.

  16. Evidence against solar influence on nuclear decay constants

    Directory of Open Access Journals (Sweden)

    S. Pommé

    2016-10-01

    Full Text Available The hypothesis that proximity to the Sun causes variation of decay constants at permille level has been tested and disproved. Repeated activity measurements of mono-radionuclide sources were performed over periods from 200 days up to four decades at 14 laboratories across the globe. Residuals from the exponential nuclear decay curves were inspected for annual oscillations. Systematic deviations from a purely exponential decay curve differ from one data set to another and are attributable to instabilities in the instrumentation and measurement conditions. The most stable activity measurements of alpha, beta-minus, electron capture, and beta-plus decaying sources set an upper limit of 0.0006% to 0.008% to the amplitude of annual oscillations in the decay rate. Oscillations in phase with Earth's orbital distance to the Sun could not be observed within a 10−6 to 10−5 range of precision. There are also no apparent modulations over periods of weeks or months. Consequently, there is no indication of a natural impediment against sub-permille accuracy in half-life determinations, renormalisation of activity to a distant reference date, application of nuclear dating for archaeology, geo- and cosmochronology, nor in establishing the SI unit becquerel and seeking international equivalence of activity standards.

  17. Search for the Decay B{sup 0} --> {rho}{sup 0} {rho}{sup 0}

    Energy Technology Data Exchange (ETDEWEB)

    Aubert, B

    2004-08-16

    The B{sup 0} --> {rho}{sup 0}{rho}{sup 0} decay mode is searched for in a data sample of about 227 million {Upsilon}(4S) --> B{bar B} decays collected with the BABAR detector at the PEP-II asymmetric B factory at SLAC. No significant signal is observed, and an upper limit of 1.1x10{sup -6} (90% C.L.) on the branching fraction is set. Implications on the penguin contribution and constraints on the CKM angle {alpha} with B --> {rho}{rho} decays are discussed. All results are preliminary.

  18. BIPAL - a data library for computing the burnup of fissionable isotopes and products of their decay

    International Nuclear Information System (INIS)

    Kralovcova, E.; Hep, J.; Valenta, V.

    1978-01-01

    The BIPAL databank contains data on 100 heavy metal isotopes starting with 206 Tl and finishing with 253 Es. Four are stable, the others are unstable. The following data are currently stored in the databank: the serial number and name of isotopes, decay modes and, for stable isotopes, the isotopic abundance (%), numbers of P decays and Q captures, numbers of corresponding final products, branching ratios, half-lives and their units, decay constants, thermal neutron captures, and fission cross sections, and other data (mainly alpha, beta and gamma intensities). The description of data and a printout of the BIPAL library are presented. (J.B.)

  19. Chain reaction

    International Nuclear Information System (INIS)

    Balogh, Brian.

    1991-01-01

    Chain Reaction is a work of recent American political history. It seeks to explain how and why America came to depend so heavily on its experts after World War II, how those experts translated that authority into political clout, and why that authority and political discretion declined in the 1970s. The author's research into the internal memoranda of the Atomic Energy Commission substantiates his argument in historical detail. It was not the ravages of American anti-intellectualism, as so many scholars have argued, that brought the experts back down to earth. Rather, their decline can be traced to the very roots of their success after World War II. The need to over-state anticipated results in order to garner public support, incessant professional and bureaucratic specialization, and the sheer proliferation of expertise pushed arcane and insulated debates between experts into public forums at the same time that a broad cross section of political participants found it easier to gain access to their own expertise. These tendencies ultimately undermined the political influence of all experts. (author)

  20. Alpha Thalassemia (For Parents)

    Science.gov (United States)

    ... the body has a problem producing alpha globin Beta thalassemia : when the body has a problem producing beta ... Transfusion Blood Test: Hemoglobin Electrophoresis Sickle Cell Disease Beta Thalassemia Blood All About Genetics Prenatal Genetic Counseling Genetic ...

  1. Simulation of Rn-222 decay products concentration deposited on a filter. Description of radon1.pas computer program

    International Nuclear Information System (INIS)

    Machaj, B.

    1996-01-01

    A computer program allowing simulation of activity distribution of 222 Rn short lived decay products deposited on a filter against time is presented, for any radiation equilibrium degree of the decay products. Deposition of the decay products is simulated by summing discrete samples every 1/10 min in the sampling time from 1 to 10 min. The concentration (activity) of the decay products is computed in one minute intervals in the range 1 - 100 min. The alpha concentration and the total activity of 218 Po + 214 Po produced are computed in the range 1 to 100 min as well. (author). 10 refs, 4 figs

  2. ALPHA-2: the sequel

    CERN Multimedia

    Katarina Anthony

    2012-01-01

    While many experiments are methodically planning for intense works over the long shutdown, there is one experiment that is already working at full steam: ALPHA-2. Its final components arrived last month and will completely replace the previous ALPHA set-up. Unlike its predecessor, this next generation experiment has been specifically designed to measure the properties of antimatter.   The ALPHA team lower the new superconducting solenoid magnet into place. The ALPHA collaboration is working at full speed to complete the ALPHA-2 set-up for mid-November – this will give them a few weeks of running before the AD shutdown on 17 December. “We really want to get some experience with this device this year so that, if we need to make any changes, we will have time during the long shutdown in which to make them,” says Jeffrey Hangst, ALPHA spokesperson. “Rather than starting the 2014 run in the commissioning stage, we will be up and running from the get go.&...

  3. Therapeutic radionuclides: Production and decay property considerations

    International Nuclear Information System (INIS)

    Volkert, W.A.; Goeckeler, W.F.; Ehrhardt, G.J.; Ketring, A.R.

    1991-01-01

    The development of effective therapeutic radiopharmaceuticals requires careful consideration in the selection of the radionuclide. The in vivo targeting and clearance properties of the carrier molecule must be balanced with the decay properties of the attached radionuclide. Radionuclides for therapeutic applications fall into three general categories: beta-particle emitters, alpha-particle emitters, and Auger and Coster-Kronig-electron emitters following electron capture. Alpha particles and Auger electrons deposit their energy over short distances with a high LET that limits the ability of cells to repair damage to DNA. Despite their high levels of cytotoxicity, the relatively short range of alpha particles requires binding of the carrier molecule to most cancer cells within a tumor in order to be effective. Because of the extremely short range of Auger electrons, the radionuclide must be carried directly into the nucleus to elicit high radiotoxicity, making it necessary to deliver the radionuclide to every cell within a tumor cell population. These characteristics impose rigid restrictions on the nature of the carrier molecules for these types of particle emitters but successful targeting of these types of radionuclides could result in high therapeutic ratios. Most beta-emitting radionuclides are produced in nuclear rectors via neutron capture reactions; however, a few are produced in charged-particle accelerators. For radionuclides produced by direct neutron activation, the quantities and specific activities that can be produced are determined in large part by the cross-section of the target isotope and the flux of the reactor. Many applications do not require high-specific activities and can therefore utilize the wide range of radionuclides that can be produced in sufficient quantity by direct neutron activation. 114 refs

  4. Fireball as a Macroscopic Manifestation of the beta-Decay of the Radioactive Phosphor into Bound States

    CERN Document Server

    Ratis, Yu L

    2004-01-01

    This paper substantiates a hypothesis that the natural fireball represents an area of space where the chain nuclear reaction of the bound state beta-decay of radioactive phosphorus nuclei takes place.

  5. Diffusion of chains in a periodic potential

    Science.gov (United States)

    Terranova, G. R.; Mártin, H. O.; Aldao, C. M.

    2017-09-01

    We studied the diffusion of 1D rigid chains in a square wave potential of period T. We considered chains of type A (composed of N particles A) and chains of type A-B (composed of N/2 particles A and N/2 particles B). The square wave potential represents domains, a lamellar structure observed for block copolymers, in which the repulsive δ energy between each A particle (B particle) of the chain and B particles (A particles) of the medium where the chains diffuse. From Monte Carlo simulations and analytical results it is found that the normalized diffusivity D, for N\\ll T , presents a universal behavior as a function of X  =  Nδ for chains of type A and X  =  (Nδ  -  lnT 2) for chains of type A-B, with and exponential decay for large values of X. For fixed values of δ and T, D is a periodic function of N with period T and 2T for chains of type A and type A-B, respectively.

  6. Selection of filter media in alpha air monitors for emergency environmental monitoring

    International Nuclear Information System (INIS)

    Kinouchi, N.; Oishi, T.; Noguchi, H.; Kato, S.

    2000-01-01

    We have developed an alpha air monitor which is possible to measure rapidly and sensitively the concentrations of airborne alpha-emitting particles, such as plutonium, for the environmental monitoring at an accident of nuclear reprocessing plant. The monitor is designed to collect airborne alpha-emitting particles by drawing the ambient air through a filter and to detect the activity by alpha spectroscopy. In order to achieve high-sensitive measurements, selection of a suitable filter used in the monitor is considerably important. The most important requirement for the filter is that it has a high surface collection efficiency to obtain the sharpness of the alpha energy spectrum. This makes it easy to distinguish the alpha-ray peak of plutonium from the alpha spectrum of naturally occurring radon decay products in the environment. And the filter is also desired to have low resistance of the air flow so that particles can be collected at a high flowrate. We have made a comparison of the surface collection efficiency and pressure drop for the various filters. Types of the test filters, most of which are commercially available in Japan, were glass fiber, cellulose-glass fiber, membrane and so on. The surface collection efficiency has been evaluated by the following two indices. One was the sharpness of alpha-ray energy peaks of thoron decay products generated in a laboratory and collected in the fibers. The other was the background counts of radon decay products in a plutonium region by measuring alpha-ray energy spectrum of radon decay products collected in the filters by sampling of dust in the atmosphere. It was found that the PTFE (polytetrafluoroethylene) membrane filter with backing had a high surface collection efficiency and low pressure drop. The results of the test are described in detail in this paper. (author)

  7. Discerning supersymmetry in adjacent branch cascade decay correlations

    Energy Technology Data Exchange (ETDEWEB)

    Graesser, Michael [Los Alamos National Laboratory; Shelton, Jessie [RUTGERS; Thomas, Scott [RUTGERS

    2008-01-01

    Many models of new physics have mass spectra that lead to production of new coloured particles which decay through long decay chains into a number of quarks and leptons. It is known that invariant mass distributions formed from the visible fermion four-momenta depend on the physical properties of intermediate particles, such as their spin, mass, chiral couplings and other interactions. Here it is emphasized that correlations between these distributions provides useful checks and tests on the underlying model and its theoretical assumptions. This is illustrated in supersymmetric models having cascade decays producing leptons, including taus. Moreover, such correlations can provide evidence on whether the symmetry stabilizing the lightest superpartner is discrete, continuous or approximately continuous. The richer phenomenology of third generation superpartners, and their interactions with neutralinos and charginos, can with sufficient luminosity be investigated with di-fermion distributions involving taus and/or signed b-quarks.

  8. Lepton asymmetry in B decays

    International Nuclear Information System (INIS)

    Wolfenstein, L.

    1998-01-01

    An estimate of the possible magnitude of the lepton asymmetry in B d decay is given in terms of observables. The asymmetry in B s decays is also discussed. It is concluded that the lepton asymmetry is not useful for detecting new physics in B-bar B mixing. copyright 1998 The American Physical Society

  9. Tau decays: A theoretical perspective

    International Nuclear Information System (INIS)

    Marciano, W.J.

    1992-11-01

    Theoretical predictions for various tau decay rates are reviewed. Effects of electroweak radiative corrections are described. Implications for precision tests of the standard model and ''new physics'' searches are discussed. A perspective on the tau decay puzzle and 1-prong problem is given

  10. Beauty hadron decays at LHCb

    CERN Document Server

    Poluektov, Anton

    2016-01-01

    In these proceedings, I will report the recent results on properties, production and decays of beauty baryons, as well as measurements of B + c meson decays, based on data collected by the LHCb collaboration at the LHC collider in 2011–2012.

  11. Status of rare decay experiments

    Energy Technology Data Exchange (ETDEWEB)

    Littenberg, L.S.

    1984-01-01

    Some results are given for rare muon decay experiments currently running. Also, plans are discussed for rare kaon decay experiments. Some of the events sought come from processes which violate lepton flavor conservation. Several apparatuses used in the search are described. 35 references. (LEW)

  12. Welding the CNGS decay tube

    CERN Multimedia

    Maximilien Brice

    2004-01-01

    3.6 km of welds were required for the 1 km long CERN Neutrinos to Gran Sasso (CNGS) decay tube, in which particles produced in the collision with a proton and a graphite target will decay into muons and muon neutrinos. Four highly skilled welders performed this delicate task.

  13. First Observation and Measurement of the Branching Fraction for the Decay $B^0_S \\rightarrow D{_S}^* K$

    CERN Multimedia

    Sestini, Lorenzo

    2015-01-01

    The Bs -> Ds* K and Bs -> Ds* \\pi decays are of paramount interest as they can be used, combined with Bs -> Ds K and Bd -> D* \\pi, to measure the weak phase \\gamma. We present the first observation of the Bs -> Ds* K decay, where Ds* are reconstructed through the decay chain Ds* -> Ds (-> K K \\pi) \\gamma, using an integrated luminosity of 3.0 fb^{-1} recorded by the LHCb experiment.

  14. A model for short alpha-neurotoxin bound to nicotinic acetylcholine receptor from Torpedo californica.

    Science.gov (United States)

    Mordvintsev, Dmitry Y; Polyak, Yakov L; Kuzmine, Dmitry A; Levtsova, Olga V; Tourleigh, Yegor V; Kasheverov, Igor E

    2006-01-01

    Short- and long-chain alpha-neurotoxins from snake venoms are potent blockers of nicotinic acetylcholine receptors (nAChRs). Short alpha-neurotoxins consist of 60-62 amino acid residues and include 4 disulfide bridges, whereas long alpha-neurotoxins have 66-75 residues and 5 disulfides. The spatial structure of these toxins is built by three loops, I-III "fingers," confined by four disulfide bridges; the fifth disulfide of long-chain alpha-neurotoxins is situated close to the tip of central loop II. An accurate knowledge of the mode of alpha-neurotoxin-nAChR interaction is important for rational design of new nAChR agonists and antagonists for medical purposes. Ideas on the topography of toxin-nAChR complexes were based until recently on nAChR interactions with selectively labeled alpha-neurotoxins, mutations in toxins, nAChR, or both. Recently, crystal structures have been solved for the Torpedo marmorata nAChR (4A[Unwin, 2005]) and for the acetylcholine-binding protein (AChBP) complexed with mollusk alpha-conotoxin (2.4 A[Celie et al., 2005]) or alpha-cobratoxin, long-chain alpha-neurotoxin (4 A [Bourne et al., 2005]). However, there were no angstrom-resolution models for complexes of short-chain alpha-neurotoxins. Here, we report the model of the Torpedo californica nAChR extracellular domain complexed to a short-chain alpha-neurotoxin II (NTII) from Naja oxiana cobra venom.

  15. Baryon helicity in B decay

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Mahiko [Department of Physics and Lawrence Berkeley National Laboratory, University of California, Berkeley, CA 94720 (United States)

    2005-07-01

    The unexpectedly large transverse polarization measured in the decay B {yields} {phi}K* poses the question whether it is accounted for as a strong interaction effect or possibly points to a hidden nonstandard weak interaction. We extend here the perturbative argument to the helicity structure of the two-body baryonic decay and discuss qualitatively on how the baryonic B decay modes might help us in understanding the issue raised by B {yields} {phi}K*. We find among others that the helicity +1/2 amplitude dominates the leading order in the B(b-barq) decay and that unlike the B {yields} VV decay the dominant amplitude is sensitive to the right-handed b {yields} s current, if any, in the penguin interaction.

  16. Top decays in extended models

    International Nuclear Information System (INIS)

    Gaitan, R.; Miranda, O. G.; Cabral-Rosetti, L. G.

    2009-01-01

    Top quark decays are interesting as a mean to test the Standard Model (SM) predictions. The Cabbibo-Kobayashi-Maskawa (CKM)-suppressed process t→cWW, and the rare decays t→cZ, t→H 0 +c, and t→cγ an excellent window to probe the predictions of theories beyond the SM. We evaluate the flavor changing neutral currents (FCNC) decay t→H 0 +c in the context of Alternative Left-Right symmetric Models (ALRM) with extra isosinglet heavy fermions; the FCNC decays may place at tree level and are only supressed by the mixing between ordinary top and charm quarks. We also comment on the decay process t→c+γ, which involves radiative corrections.

  17. Analysis of new physics in B decays

    Energy Technology Data Exchange (ETDEWEB)

    Feger, Robert

    2010-03-26

    The inclusive semileptonic decay B{yields}X{sub c}l{nu} yields the best extracted value of vertical stroke V{sub cb} vertical stroke with an uncertainty of about 2%, which is due to its precise theoretical description by the heavy-quark expansion (HQE) and the large amount of data collected by the B factories Babar and Belle. Besides the precision determination of vertical stroke V{sub cb} vertical stroke and the HQE parameter it also enables us to test for new physics effects. Normal decays with a small standard model contribution are investigated on the quest for new physics, like flavour-changing neutral currents, which are suppressed in the standard model by the GIM mechanism. But as right-handed weak currents are absent in the standard model their appearance would be a smoking gun signal for new physics in the decay considered here. We perform such an analysis, which is known form the leptonic sector as ''Michel parameter analysis''. Contributions from possible new physics effects are derived with effective field theory methods, yielding an enhanced b {yields} c current, with not only a right-handed vector contribution, but also scalar and tensor couplings. We repeat the computations of the decay with the enhanced current up to O(1/m{sub b}{sup 2}) in the HQE and up to O({alpha}{sub s}) in the perturbative corrections. A moment analysis of the moments of the lepton energy spectrum and the hadronic invariant mass has become a reliable tool in both the theoretical evaluation and the experimental determination. This combines in a HQE fit, which has been improved frequently, yielding a precise determination of the HQE parameters and especially the best extracted value for vertical stroke V{sub cb} vertical stroke. The HQE fit may as well serve as a test for new physics effects in these moments. The theoretical analysis of the moments reveals a low sensitivity of the moments on the non-vector currents. Thus we perform the fit with only a

  18. Carbohydrate as covalent crosslink in human inter-alpha-trypsin inhibitor

    DEFF Research Database (Denmark)

    Jessen, T E; Faarvang, K L; Ploug, M

    1988-01-01

    The primary structure of inter-alpha-trypsin inhibitor is partially elucidated, but controversy about the construction of the polypeptide backbone still exists. We present evidence suggesting that inter-alpha-trypsin inhibitor represents a novel plasma protein structure with two separate polypept...... polypeptide chains covalently crosslinked only by carbohydrate (chondroitin sulphate)....

  19. Hemoglobin alpha 2 gene +861 G>A polymorphism in Turkish ...

    African Journals Online (AJOL)

    Dilay Ciglidag Dungul

    Alpha thalassemia is caused by mutations in the alpha chain of the hemoglobin molecule. ... According to Human Gene Mutation Database (HGMD) more than 48 different .... Electroferogram of the DNA sequence, showing a G to A polymorphism in the downstream untranslated region of the HBA2 gene. Table 3 The ...

  20. Cold valleys in the radioactive decay of 248− 254Cf isotopes

    Indian Academy of Sciences (India)

    Computed half-lives for alpha decay agree with experimental values within two orders of magnitude. The most probable clusters from these parents are predicted to be 46Ar, 48,50Ca which indicate the role of doubly or near doubly magic clusters in cluster radioactivity. Odd A clusters are found to be favorable for emission ...

  1. DECAY MODES OF HIGH-LYING SINGLE-PARTICLE STATES IN PB-209

    NARCIS (Netherlands)

    BEAUMEL, D; FORTIER, S; GALES, S; GUILLOT, J; LANGEVINJOLIOT, H; LAURENT, H; MAISON, JM; VERNOTTE, J; BORDEWIJK, JA; BRANDENBURG, S; KRASZNAHORKAY, A; CRAWLEY, GM; MASSOLO, CP; RENTERIA, M

    The neutron decay of high-lying single-particle states in Pb-209 excited by means of the (alpha, He-3) reaction has been investigated at 122 MeV incident energy using a multidetector array. The high-spin values of these states, inferred from previous inclusive experiments, are confirmed by the

  2. Cold valleys in the radioactive decay of 248−254Cf isotopes

    Indian Academy of Sciences (India)

    Abstract. Based on the concept of cold valley in cold fission and fusion, we have in- vestigated the cluster decay process in 248−254Cf isotopes. In addition to alpha particle minima, other deep minima occur for S, Ar and Ca clusters. It is found that inclusion of proximity potential does not change the position of minima but ...

  3. Cold valleys in the radioactive decay of 248-254 Cf isotopes

    Indian Academy of Sciences (India)

    Based on the concept of cold valley in cold fission and fusion, we have investigated the cluster decay process in 248-254Cf isotopes. In addition to alpha particle minima, other deep minima occur for S, Ar and Ca clusters. It is found that inclusion of proximity potential does not change the position of minima but minima ...

  4. Monte Carlo alpha calculation

    Energy Technology Data Exchange (ETDEWEB)

    Brockway, D.; Soran, P.; Whalen, P.

    1985-01-01

    A Monte Carlo algorithm to efficiently calculate static alpha eigenvalues, N = ne/sup ..cap alpha..t/, for supercritical systems has been developed and tested. A direct Monte Carlo approach to calculating a static alpha is to simply follow the buildup in time of neutrons in a supercritical system and evaluate the logarithmic derivative of the neutron population with respect to time. This procedure is expensive, and the solution is very noisy and almost useless for a system near critical. The modified approach is to convert the time-dependent problem to a static ..cap alpha../sup -/eigenvalue problem and regress ..cap alpha.. on solutions of a/sup -/ k/sup -/eigenvalue problem. In practice, this procedure is much more efficient than the direct calculation, and produces much more accurate results. Because the Monte Carlo codes are intrinsically three-dimensional and use elaborate continuous-energy cross sections, this technique is now used as a standard for evaluating other calculational techniques in odd geometries or with group cross sections.

  5. Measurements of the CKM Angle Alpha at BaBar

    Energy Technology Data Exchange (ETDEWEB)

    Stracka, Simone; /Milan U. /INFN, Milan

    2012-04-04

    The authors present improved measurements of the branching fractions and CP-asymmetries fin the B{sup 0} {yields} {pi}{sup +}{pi}{sup -}, B{sup 0} {yields} {pi}{sup 0}{pi}{sup 0}, and B{sup +} {yields} {rho}{sup +}{rho}{sup 0} decays, which impact the determination of {alpha}. The combined branching fractions of B {yields} K{sub 1}(1270){pi} and B {yields} K{sub 1}(1400){pi} decays are measured for the first time and allow a novel determination of {alpha} in the B{sup 0} {yields} {alpha}{sub 1}(1260){sup {+-}}{pi}{sup {-+}} decay channel. These measurements are performed using the final dataset collected by the BaBar detector at the PEP-II B-factory. The primary goal of the experiments based at the B factories is to test the Cabibbo-Kobayashi-Maskawa (CKM) picture of CP violation in the standard model of electroweak interactions. This can be achieved by measuring the angles and sides of the Unitarity Triangle in a redundant way.

  6. Experimental study of the cross-sections of alpha-particle induced reactions on $^{209}$Bi

    CERN Document Server

    Hermanne, A; Shubin, Yu N; Szucs, Z; Takács, S; Tarkanyi, F; 10.1016/j.apradiso.2005.01.015

    2005-01-01

    alpha -particle-induced nuclear reactions for generation of /sup 211 /At used in therapeutic nuclear medicine and possible contaminants were investigated with the stacked foil activation technique on natural bismuth targets up to E/sub alpha /=39 MeV. Excitation functions are reported for the reactions /sup 209/Bi( alpha ,2n)/sup 211/At, /sup 209/Bi( alpha ,3n)/sup 210/At and /sup 209/Bi( alpha , x)/sup 210/Po. Results obtained from direct alpha -emission measurements and gamma -spectra from decay products are compared and correspond well with earlier literature values. Thick target yields have been deduced from the experimental cross-sections and optimised production pathways for minimal contamination are presented. A comparison with the results of the theoretical model code ALICE-IPPE is discussed.

  7. Evidence of an alpha 2-macroglobulin-like molecule in plasma of Salamandra salamandra. Structural and functional similarity with human alpha 2-macroglobulin.

    Science.gov (United States)

    Sallenave, J M; Bellot, R

    1987-07-13

    A high-Mr (Mr 750,000) alpha 1-macroglobulin, obtained from Salamandra salamandra, is described. Salamander alpha 1-macroglobulin is composed of two monomers of equal Mr, which are composed of two polypeptide chains, each of Mr 180,000, linked by disulfide bonds. The molecular parameters of this protein, its binding to trypsin and inactivation by methylamine suggest that salamander alpha 1-macroglobulin is closely related to human alpha 2-macroglobulin and to other related proteins described in the animal kingdom.

  8. Determination of Uranium, Thorium and Radium 226 in Zircon containig sands by alpha spectrometry

    International Nuclear Information System (INIS)

    Spezzano, P.

    1985-01-01

    The industrial utilization of Zircon sands for the production of refractories presents radiological problems owing to the risk of inhalation of Uranium, Thorium and their decay products, present in high concentrations in such materials. A method of analysis was realized for the determination of Uranium, Thorium and Radium-226 in Zircon sands, including the total dissolution of the sample, radiochemical separation and final measurement by alpha spectrometry with surface barrier detector. The concentrations of the main alpha-emitting radionuclides presents in two samples of Zircon sands have been determined and the possibility of disequilibrium along the decay series has been pointed out

  9. Decaying dark matter in supersymmetric SU(5) models

    International Nuclear Information System (INIS)

    Luo Mingxing; Wang Liucheng; Wu Wei; Zhu Guohuai

    2010-01-01

    Motivated by recent observations from PAMELA, Fermi and H.E.S.S., we consider dark matter decays in the framework of supersymmetric SU(5) grand unification theories. An SU(5) singlet S is assumed to be the main component of dark matters, which decays into visible particles through dimension six operators suppressed by the grand unification scale. Under certain conditions, S decays dominantly into a pair of sleptons with universal coupling for all generations. Subsequently, electrons and positrons are produced from cascade decays of these sleptons. These cascade decay chains smooth the e + +e - spectrum, which permit naturally a good fit to the Fermi-LAT data. The observed positron fraction upturn by PAMELA can be reproduced simultaneously. We have also calculated diffuse gamma-ray spectra due to the e ± excesses and compared them with the preliminary Fermi-LAT data from 0.1 GeV to 10 GeV in the region 0 deg. ≤l≤ 360 deg., 10 deg. ≤|b|≤20 deg. The photon spectrum of energy above 100 GeV, mainly from final state radiations, may be checked in the near future.

  10. β decay of neutron-rich 53-56Ca

    International Nuclear Information System (INIS)

    Mantica, P. F.; Crawford, H. L.; Damaske, A.; Pinter, J. S.; Stoker, J. B.; Broda, R.; Fornal, B.; Hecht, A. A.; Hoteling, N.; Hoffman, C.; Tabor, S. L.; Walters, W. B.; Horoi, M.; Janssens, R. V. F.; Zhu, S.; Pereira, J.; Sumikama, T.; Wang, X.

    2008-01-01

    β-decay properties of neutron-rich Ca isotopes have been obtained. Half-life values were determined for the first time for 54 Ca (86±7 ms), 55 Ca (22±2 ms), and 56 Ca (11±2 ms). The half-life of 230±60 ms deduced for 53 Ca is significantly longer than reported previously, where the decay chain 53 K → 53 Ca → 53 Sc was considered. A delayed γ ray with an energy of 247 keV was identified following β decay of 54 Ca and is proposed to depopulate the 1 1 + level in 54 Sc. The β-decay properties compare favorably with the results of shell-model calculations completed in the full pf space with the GXPF1 interaction. The half-lives of the neutron-rich Ca isotopes are also compared with gross β-decay theory. The systematic trend of the neutron-rich Ca half-lives is consistent with the presence of a subshell gap at N=32

  11. MIRD radionuclide data and decay schemes

    CERN Document Server

    Eckerman, Keith F

    2007-01-01

    For all physicians, scientists, and physicists working in the nuclear medicine field, the MIRD: Radionuclide Data and Decay Schemes updated edition is an essential sourcebook for radiation dosimetry and understanding the properties of radionuclides. Includes CD Table of Contents Decay schemes listed by atomic number Radioactive decay processes Serial decay schemes Decay schemes and decay tables This essential reference for nuclear medicine physicians, scientists and physicists also includes a CD with tabulations of the radionuclide data necessary for dosimetry calculations.

  12. Monte Carlo alpha deposition

    International Nuclear Information System (INIS)

    Talley, T.L.; Evans, F.

    1988-01-01

    Prior work demonstrated the importance of nuclear scattering to fusion product energy deposition in hot plasmas. This suggests careful examination of nuclear physics details in burning plasma simulations. An existing Monte Carlo fast ion transport code is being expanded to be a test bed for this examination. An initial extension, the energy deposition of fast alpha particles in a hot deuterium plasma, is reported. The deposition times and deposition ranges are modified by allowing nuclear scattering. Up to 10% of the initial alpha particle energy is carried to greater ranges and times by the more mobile recoil deuterons. 4 refs., 5 figs., 2 tabs

  13. Buffett’s Alpha

    DEFF Research Database (Denmark)

    Frazzini, Andrea; Kabiller, David; Heje Pedersen, Lasse

    Berkshire Hathaway has realized a Sharpe ratio of 0.76, higher than any other stock or mutual fund with a history of more than 30 years, and Berkshire has a significant alpha to traditional risk factors. However, we find that the alpha becomes insignificant when controlling for exposures to Betting......-Against-Beta and Quality-Minus-Junk factors. Further, we estimate that Buffett’s leverage is about 1.6-to-1 on average. Buffett’s returns appear to be neither luck nor magic, but, rather, reward for the use of leverage combined with a focus on cheap, safe, quality stocks. Decomposing Berkshires’ portfolio into ownership...

  14. Inflaton decay through supergravity effects

    International Nuclear Information System (INIS)

    Endo, Motoi; Kawasaki, Masahiro; Takahashi, Fuminobu; Yanagida, T.T.

    2006-01-01

    We point out that supergravity effects enable the inflaton to decay into all matter fields, including the visible and the supersymmetry breaking sectors, once the inflaton acquires a non-vanishing vacuum expectation value. The new decay processes have great impacts on cosmology; the reheating temperature is bounded below; the gravitinos are produced by the inflaton decay in a broad class of the dynamical supersymmetry breaking models. We derive the bounds on the inflaton mass and the vacuum expectation value, which severely constrain high-scale inflations such as the hybrid and chaotic inflation models

  15. Charm counting in b decays

    CERN Document Server

    Buskulic, Damir; Décamp, D; Ghez, P; Goy, C; Lees, J P; Lucotte, A; Minard, M N; Nief, J Y; Odier, P; Pietrzyk, B; Casado, M P; Chmeissani, M; Crespo, J M; Delfino, M C; Efthymiopoulos, I; Fernández, E; Fernández-Bosman, M; Carrido, L; Juste, A; Martínez, M; Orteu, S; Padilla, C; Park, I C; Pascual, A; Perlas, J A; Riu, I; Sánchez, F; Teubert, F; Colaleo, A; Creanza, D; De Palma, M; Gelao, G; Girone, M; Iaselli, Giuseppe; Maggi, G; Maggi, M; Marinelli, N; Nuzzo, S; Ranieri, A; Raso, G; Ruggieri, F; Selvaggi, G; Silvestris, L; Tempesta, P; Tricomi, A; Zito, G; Huang, X; Lin, J; Ouyang, Q; Wang, T; Xie, Y; Xu, R; Xue, S; Zhang, J; Zhang, L; Zhao, W; Alemany, R; Bazarko, A O; Bonvicini, G; Bright-Thomas, P G; Cattaneo, M; Cerutti, F; Comas, P; Coyle, P; Drevermann, H; Forty, Roger W; Frank, M; Hagelberg, R; Harvey, J; Janot, P; Jost, B; Kneringer, E; Knobloch, J; Lehraus, Ivan; Lutters, G; Martin, E B; Mato, P; Minten, Adolf G; Miquel, R; Mir, L M; Moneta, L; Oest, T; Pacheco, A; Pusztaszeri, J F; Ranjard, F; Rensing, P E; Rizzo, G; Rolandi, Luigi; Schlatter, W D; Schmelling, M; Schmitt, M; Schneider, O; Tejessy, W; Tomalin, I R; Venturi, A; Wachsmuth, H W; Wagner, A; Ajaltouni, Ziad J; Barrès, A; Boyer, C; Falvard, A; Gay, P; Guicheney, C; Henrard, P; Jousset, J; Michel, B; Monteil, S; Montret, J C; Pallin, D; Perret, P; Podlyski, F; Proriol, J; Rosnet, P; Rossignol, J M; Fearnley, Tom; Hansen, J B; Hansen, J D; Hansen, J R; Hansen, P H; Nilsson, B S; Rensch, B; Wäänänen, A; Kyriakis, A; Markou, C; Simopoulou, Errietta; Siotis, I; Vayaki, Anna; Zachariadou, K; Blondel, A; Bonneaud, G R; Brient, J C; Bourdon, P; Rougé, A; Rumpf, M; Valassi, Andrea; Verderi, M; Videau, H L; Candlin, D J; Parsons, M I; Focardi, E; Parrini, G; Corden, M; Georgiopoulos, C H; Jaffe, D E; Antonelli, A; Bencivenni, G; Bologna, G; Bossi, F; Campana, P; Capon, G; Casper, David William; Chiarella, V; Felici, G; Laurelli, P; Mannocchi, G; Murtas, F; Murtas, G P; Passalacqua, L; Pepé-Altarelli, M; Curtis, L; Dorris, S J; Halley, A W; Knowles, I G; Lynch, J G; O'Shea, V; Raine, C; Reeves, P; Scarr, J M; Smith, K; Teixeira-Dias, P; Thompson, A S; Thomson, F; Thorn, S; Turnbull, R M; Becker, U; Geweniger, C; Graefe, G; Hanke, P; Hansper, G; Hepp, V; Kluge, E E; Putzer, A; Schmidt, M; Sommer, J; Tittel, K; Werner, S; Wunsch, M; Abbaneo, D; Beuselinck, R; Binnie, David M; Cameron, W; Dornan, Peter J; Moutoussi, A; Nash, J; Sedgbeer, J K; Stacey, A M; Williams, M D; Dissertori, G; Girtler, P; Kuhn, D; Rudolph, G; Betteridge, A P; Bowdery, C K; Colrain, P; Crawford, G; Finch, A J; Foster, F; Hughes, G; Sloan, Terence; Williams, M I; Galla, A; Giehl, I; Greene, A M; Hoffmann, C; Jakobs, K; Kleinknecht, K; Quast, G; Renk, B; Rohne, E; Sander, H G; Van Gemmeren, P; Zeitnitz, C; Aubert, Jean-Jacques; Bencheikh, A M; Benchouk, C; Bonissent, A; Bujosa, G; Calvet, D; Carr, J; Diaconu, C A; Etienne, F; Konstantinidis, N P; Payre, P; Rousseau, D; Talby, M; Sadouki, A; Thulasidas, M; Trabelsi, K; Aleppo, M; Ragusa, F; Bauer, C; Berlich, R; Blum, Walter; Büscher, V; Dietl, H; Dydak, Friedrich; Ganis, G; Gotzhein, C; Kroha, H; Lütjens, G; Lutz, Gerhard; Männer, W; Moser, H G; Richter, R H; Rosado-Schlosser, A; Schael, S; Settles, Ronald; Seywerd, H C J; Saint-Denis, R; Stenzel, H; Wiedenmann, W; Wolf, G; Boucrot, J; Callot, O; Choi, Y; Cordier, A; Davier, M; Duflot, L; Grivaz, J F; Heusse, P; Höcker, A; Jacholkowska, A; Jacquet, M; Kim, D W; Le Diberder, F R; Lefrançois, J; Lutz, A M; Nikolic, I A; Park, H J; Schune, M H; Simion, S; Veillet, J J; Videau, I; Zerwas, D; Azzurri, P; Bagliesi, G; Batignani, G; Bettarini, S; Bozzi, C; Calderini, G; Carpinelli, M; Ciocci, M A; Ciulli, V; Dell'Orso, R; Fantechi, R; Ferrante, I; Foà, L; Forti, F; Giassi, A; Giorgi, M A; Gregorio, A; Ligabue, F; Lusiani, A; Marrocchesi, P S; Messineo, A; Palla, Fabrizio; Sanguinetti, G; Sciabà, A; Spagnolo, P; Steinberger, Jack; Tenchini, Roberto; Tonelli, G; Vannini, C; Verdini, P G; Blair, G A; Bryant, L M; Chambers, J T; Gao, Y; Green, M G; Medcalf, T; Perrodo, P; Strong, J A; Von Wimmersperg-Töller, J H; Botterill, David R; Clifft, R W; Edgecock, T R; Haywood, S; Maley, P; Norton, P R; Thompson, J C; Wright, A E; Bloch-Devaux, B; Colas, P; Emery, S; Kozanecki, Witold; Lançon, E; Lemaire, M C; Locci, E; Pérez, P; Rander, J; Renardy, J F; Roussarie, A; Schuller, J P; Schwindling, J; Trabelsi, A; Vallage, B; Black, S N; Dann, J H; Johnson, R P; Kim, H Y; Litke, A M; McNeil, M A; Taylor, G; Booth, C N; Boswell, R; Brew, C A J; Cartwright, S L; Combley, F; Köksal, A; Lehto, M H; Newton, W M; Reeve, J; Thompson, L F; Böhrer, A; Brandt, S; Cowan, G D; Grupen, Claus; Minguet-Rodríguez, J A; Rivera, F; Saraiva, P; Smolik, L; Stephan, F; Apollonio, M; Bosisio, L; Della Marina, R; Giannini, G; Gobbo, B; Musolino, G; Rothberg, J E; Wasserbaech, S R; Armstrong, S R; Elmer, P; Feng, Z; Ferguson, D P S; Gao, Y S; González, S; Grahl, J; Greening, T C; Hayes, O J; Hu, H; McNamara, P A; Nachtman, J M; Orejudos, W; Pan, Y B; Saadi, Y; Scott, I J; Walsh, A M; Walsh, J; Wu, X; Yamartino, J M; Zheng, M; Zobernig, G

    1996-01-01

    The inclusive production of charmed particles in Z -> bb decays has been measured from the yield of D^0, D^+, D^+_s and Lambda_{c}^+ decays in a sample of qq events with high b purity collected with the ALEPH detector from 1992 to 1995. From these measurements, adding the charmonia production rate and an estimate of the charmed strange baryon contribution, the average number of charm quarks per b decay is determined to be n_c = 1.230 \\pm 0.036 \\pm 0.038 \\pm 0.053 where the uncertainties are due to statistics, systematic effects and branching ratios, respectively.

  16. Charm counting in b decays

    Science.gov (United States)

    Buskulic, D.; de Bonis, I.; Decamp, D.; Ghez, P.; Goy, C.; Lees, J.-P.; Lucotte, A.; Minard, M.-N.; Nief, J.-Y.; Odier, P.; Pietrzyk, B.; Casado, M. P.; Chmeissani, M.; Crespo, J. M.; Delfino, M.; Efthymiopoulos, I.; Fernandez, E.; Fernandez-Bosman, M.; Garrido, Ll.; Juste, A.; Martinez, M.; Orteu, S.; Padilla, C.; Park, I. C.; Pascual, A.; Perlas, J. A.; Riu, I.; Sanchez, F.; Teubert, F.; Colaleo, A.; Creanza, D.; de Palma, M.; Gelao, G.; Girone, M.; Iaselli, G.; Maggi, G.; Maggi, M.; Marinelli, N.; Nuzzo, S.; Ranieri, A.; Raso, G.; Ruggieri, F.; Selvaggi, G.; Silvestris, L.; Tempesta, P.; Tricomi, A.; Zito, G.; Huang, X.; Lin, J.; Ouyang, Q.; Wang, T.; Xie, Y.; Xu, R.; Xue, S.; Zhang, J.; Zhang, L.; Zhao, W.; Alemany, R.; Bazarko, A. O.; Bonvicini, G.; Bright-Thomas, P.; Cattaneo, M.; Cerutti, F.; Comas, P.; Coyle, P.; Drevermann, H.; Forty, R. W.; Frank, M.; Hagelberg, R.; Harvey, J.; Janot, P.; Jost, B.; Kneringer, E.; Knobloch, J.; Lehraus, I.; Lutters, G.; Martin, E. B.; Mato, P.; Minten, A.; Miquel, R.; Mir, Ll. M.; Moneta, L.; Oest, T.; Pacheco, A.; Pusztaszeri, J.-F.; Ranjard, F.; Rensing, P.; Rizzo, G.; Rolandi, L.; Schlatter, D.; Schmelling, M.; Schmitt, M.; Schneider, O.; Tejessy, W.; Tomalin, I. R.; Venturi, A.; Wachsmuth, H.; Wagner, A.; Ajaltouni, Z.; Barrès, A.; Boyer, C.; Falvard, A.; Gay, P.; Guicheney, C.; Henrard, P.; Jousset, J.; Michel, B.; Monteil, S.; Montret, J.-C.; Pallin, D.; Perret, P.; Podlyski, F.; Proriol, J.; Rosnet, P.; Rossignol, J.-M.; Fearnley, T.; Hansen, J. B.; Hansen, J. D.; Hansen, J. R.; Hansen, P. H.; Nilsson, B. S.; Rensch, B.; Wäänänen, A.; Kyriakis, A.; Markou, C.; Simopoulou, E.; Siotis, I.; Vayaki, A.; Zachariadou, K.; Blondel, A.; Bonneaud, G.; Brient, J. C.; Bourdon, P.; Rougé, A.; Rumpf, M.; Valassi, A.; Verderi, M.; Videau, H.; Candlin, D. J.; Parsons, M. I.; Focardi, E.; Parrini, G.; Corden, M.; Georgiopoulos, C.; Jaffe, D. E.; Antonelli, A.; Bencivenni, G.; Bologna, G.; Bossi, F.; Campana, P.; Capon, G.; Casper, D.; Chiarella, V.; Felici, G.; Laurelli, P.; Mannocchi, G.; Murtas, F.; Murtas, G. P.; Passalacqua, L.; Pepe-Altarelli, M.; Curtis, L.; Dorris, S. J.; Halley, A. W.; Knowles, I. G.; Lynch, J. G.; O'Shea, V.; Raine, C.; Reeves, P.; Scarr, J. M.; Smith, K.; Teixeira-Dias, P.; Thompson, A. S.; Thomson, F.; Thorn, S.; Turnbull, R. M.; Becker, U.; Geweniger, C.; Graefe, G.; Hanke, P.; Hansper, G.; Hepp, V.; Kluge, E. E.; Putzer, A.; Schmidt, M.; Sommer, J.; Stenzel, H.; Tittel, K.; Werner, S.; Wunsch, M.; Abbaneo, D.; Beuselinck, R.; Binnie, D. M.; Cameron, W.; Dornan, P. J.; Moutoussi, A.; Nash, J.; Sedgbeer, J. K.; Stacey, A. M.; Williams, M. D.; Dissertori, G.; Girtler, P.; Kuhn, D.; Rudolph, G.; Betteridge, A. P.; Bowdery, C. K.; Colrain, P.; Crawford, G.; Finch, A. J.; Foster, F.; Hughes, G.; Sloan, T.; Williams, M. I.; Galla, A.; Giehl, I.; Greene, A. M.; Hoffmann, C.; Jakobs, K.; Kleinknecht, K.; Quast, G.; Renk, B.; Rohne, E.; Sander, H.-G.; van Gemmeren, P.; Zeitnitz, C.; Aubert, J. J.; Bencheikh, A. M.; Benchouk, C.; Bonissent, A.; Bujosa, G.; Calvet, D.; Carr, J.; Diaconu, C.; Etienne, F.; Konstantinidis, N.; Payre, P.; Rousseau, D.; Talby, M.; Sadouki, A.; Thulasidas, M.; Trabelsi, K.; Aleppo, M.; Ragusa, F.; Bauer, C.; Berlich, R.; Blum, W.; Büscher, V.; Dietl, H.; Dydak, F.; Ganis, G.; Gotzhein, C.; Kroha, H.; Lütjens, G.; Lutz, G.; Männer, W.; Moser, H.-G.; Richter, R.; Rosado-Schlosser, A.; Schael, S.; Settles, R.; Seywerd, H.; Denis, R. St.; Stenzel, H.; Wiedenmann, W.; Wolf, G.; Boucrot, J.; Callot, O.; Choi, Y.; Cordier, A.; Davier, M.; Duflot, L.; Grivaz, J.-F.; Heusse, Ph.; Höcker, A.; Jacholkowska, A.; Jacquet, M.; Kim, D. W.; Le Diberder, F.; Lefrançois, J.; Lutz, A.-M.; Nikolic, I.; Park, H. J.; Schune, M.-H.; Simion, S.; Veillet, J.-J.; Videau, I.; Zerwas, D.; Azzurri, P.; Bagliesi, G.; Batignani, G.; Bettarini, S.; Bozzi, C.; Calderini, G.; Carpinelli, M.; Ciocci, M. A.; Ciulli, V.; Dell'Orso, R.; Fantechi, R.; Ferrante, I.; Foà, L.; Forti, F.; Giassi, A.; Giorgi, M. A.; Gregorio, A.; Ligabue, F.; Lusiani, A.; Marrocchesi, P. S.; Messineo, A.; Palla, F.; Sanguinetti, G.; Sciabà, A.; Spagnolo, P.; Steinberger, J.; Tenchini, R.; Tonelli, G.; Vannini, C.; Verdini, P. G.; Blair, G. A.; Bryant, L. M.; Chambers, J. T.; Gao, Y.; Green, M. G.; Medcalf, T.; Perrodo, P.; Strong, J. A.; von Wimmersperg-Toeller, J. H.; Botterill, D. R.; Clifft, R. W.; Edgecock, T. R.; Haywood, S.; Maley, P.; Norton, P. R.; Thompson, J. C.; Wright, A. E.; Bloch-Devaux, B.; Colas, P.; Emery, S.; Kozanecki, W.; Lançon, E.; Lemaire, M. C.; Locci, E.; Perez, P.; Rander, J.; Renardy, J.-F.; Roussarie, A.; Schuller, J.-P.; Schwindling, J.; Trabelsi, A.; Vallage, B.; Black, S. N.; Dann, J. H.; Johnson, R. P.; Kim, H. Y.; Litke, A. M.; McNeil, M. A.; Taylor, G.; Booth, C. N.; Boswell, R.; Brew, C. A. J.; Cartwright, S.; Combley, F.; Koksal, A.; Letho, M.; Newton, W. M.; Reeve, J.; Thompson, L. F.; Böhrer, A.; Brandt, S.; Cowan, G.; Grupen, C.; Minguet-Rodriguez, J.; Rivera, F.; Saraiva, P.; Smolik, L.; Stephan, F.; Apollonio, M.; Bosisio, L.; Della Marina, R.; Giannini, G.; Gobbo, B.; Musolino, G.; Rothberg, J.; Wasserbaech, S.; Armstrong, S. R.; Elmer, P.; Feng, Z.; Ferguson, D. P. S.; Gao, Y. S.; González, S.; Grahl, J.; Greening, T. C.; Hayes, O. J.; Hu, H.; McNamara, P. A.; Nachtman, J. M.; Orejudos, W.; Pan, Y. B.; Saadi, Y.; Scott, I. J.; Walsh, A. M.; Walsh, J.; Wu, Sau Lan; Wu, X.; Yamartino, J. M.; Zheng, M.; Zobernig, G.; Aleph Collaboration

    1996-02-01

    The inclusive production of charmed particles in Z → b overlineb decays has been measured from the yield of D0, D+, Ds+ and Λc+ decays in a sample of q overlineq events with high b purity collected with the ALEPH detector from 1992 to 1995. From these measurements, adding the charmonia production rate and an estimate of the charmed strange baryon contribution, the average number of charm quarks per b decay is determined to be nc = 1.230 ± 0.036 ± 0.038 ± 0.053, where the uncertainties are due to statistics, systematic effects and branching ratios, respectively.

  17. Three-body decays: structure, decay mechanism and fragment properties

    International Nuclear Information System (INIS)

    Alvarez-Rodriguez, R.; Jensen, A.S.; Fedorov, D.V.; Fynbo, H.O.U.; Kirsebom, O.S.; Garrido, E.

    2009-01-01

    We discuss the three-body decay mechanisms of many-body resonances. R-matrix sequential description is compared with full Faddeev computation. The role of the angular momentum and boson symmetries is also studied. As an illustration we show the computed ?-particle energy distribution after the decay of 12 C(1 + ) resonance at 12.7 MeV. This article is based on the presentation by R. Alvarez-Rodriguez at the Fifth Workshop on Critical Stability, Erice, Sicily. (author)

  18. alpha-Globin genes: thalassemic and structural alterations in a Brazilian population

    Directory of Open Access Journals (Sweden)

    M.R.S.C. Wenning

    2000-09-01

    Full Text Available Seven unrelated patients with hemoglobin (Hb H disease and 27 individuals with alpha-chain structural alterations were studied to identify the alpha-globin gene mutations present in the population of Southeast Brazil. The -alpha3.7, --MED and -(alpha20.5 deletions were investigated by PCR, whereas non-deletional alpha-thalassemia (alphaHphalpha, alphaNcoIalpha, aaNcoI, alphaIcalpha and alphaTSaudialpha was screened with restriction enzymes and by nested PCR. Structural alterations were identified by direct DNA sequencing. Of the seven patients with Hb H disease, all of Italian descent, two had the -(alpha20.5/-alpha3.7 genotype, one had the --MED/-alpha3.7 genotype, one had the --MED/alphaHphalpha genotype and three showed interaction of the -alpha3.7 deletion with an unusual, unidentified form of non-deletional alpha-thalassemia [-alpha3.7/(aaT]. Among the 27 patients with structural alterations, 15 (of Italian descent had Hb Hasharon (alpha47Asp->His associated with the -alpha3.7 deletion, 4 (of Italian descent were heterozygous for Hb J-Rovigo (alpha53Ala->Asp, 4 (3 Blacks and 1 Caucasian were heterozygous for Hb Stanleyville-II (alpha78Asn->Lys associated with the alpha+-thalassemia, 1 (Black was heterozygous for Hb G-Pest (alpha74Asp->Asn, 1 (Caucasian was heterozygous for Hb Kurosaki (alpha7Lys->Glu, 1 (Caucasian was heterozygous for Hb Westmead (alpha122His->Gln, and 1 (Caucasian was the carrier of a novel silent variant (Hb Campinas, alpha26Ala->Val. Most of the mutations found reflected the Mediterranean and African origins of the population. Hbs G-Pest and Kurosaki, very rare, and Hb Westmead, common in southern China, were initially described in individuals of ethnic origin differing from those of the carriers reported in the present study and are the first cases to be reported in the Brazilian population.

  19. Long-range alpha detection applied to soil surface monitoring

    International Nuclear Information System (INIS)

    Caress, R.W.; Allander, K.S.; Bounds, J.A.; Catlett, M.M.; MacArthur, D.W.; Rutherford, D.A.

    1992-01-01

    The long-range alpha detection (LRAD) technique depends on the detection of ion pairs generated by alpha particles losing energy in air rather than on detection of the alpha particles themselves. Typical alpha particles generated by uranium will travel less than 3 cm in air. In contrast, the ions have been successfully detected many inches or feet away from the contamination. Since LRAD detection systems are sensitive to all ions simultaneously, large LRAD soil surface monitors (SSMS) can be used to collect all of the ions from a large sample. The LRAD SSMs are designed around the fan-less LRAD detector. In this case a five-sided box with an open bottom is placed on the soil surface. Ions generated by alpha decays on the soil surface are collected on a charged copper plate within the box. These ions create a small current from the plate to ground which is monitored with a sensitive electrometer. The current measured is proportional to the number of ions in the box, which is, in turn, proportional to the amount of alpha contamination on the surface of the soil. This report includes the design and construction of a 1-m by 1-m SSM as well as the results of a study at Fernald, OH, as part of the Uranium in Soils Integrated Demonstration

  20. Radiative Leptonic B Decays

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Edward Tann [California Inst. of Technology (CalTech), Pasadena, CA (United States)

    2007-01-01

    We present the results of a search for B+ meson decays into γℓ+v, where ℓ = e,μ. We use a sample of 232 million B$\\bar{B}$ meson pairs recorded at the Υ(4S) resonance with the BABAR detector at the PEP-II B factory. We measure a partial branching fraction Δβ in a restricted region of phase space that reduces the effect of theoretical uncertainties, requiring the lepton energy to be in the range 1.875 and 2.850 GeV, the photon energy to be in the range 0.45 and 2.35 GeV, and the cosine of the angle between the lepton and photon momenta to be less than -0.36, with all quantities computed in the Υ(4S) center-of-mass frame. We find Δβ(B+ → γℓ+v) = (-0.31.5+1.3(statistical) -0.6+0.6(systematic) ± 0.1(theoretical)) x 10-6, under the assumption of lepton universality. Interpreted as a 90% confidence-level Bayesian upper limit, the result corresponds to 1.7 x 10-6 for a prior at in amplitude, and 2.3 x 10-6 for a prior at in branching fraction.

  1. Radioactive decay data tables: A handbook of decay data for application to radiation dosimetry and radiological assessments

    Science.gov (United States)

    Kocher, D. C.; Smith, J. S.

    Decay data are presented for approximately 500 radionuclides including those occurring naturally in the environment, those of potential importance in routine or accidental releases from the nuclear fuel cycle, those of current interest in nuclear medicine and fusion reactor technology, and some of those of interest to Committee 2 of the International Commission on Radiological Protection for the estimation of annual limits on intake via inhalation and ingestion for occupationally exposed individuals. Physical processes involved in radioactive decay which produce the different types of radiation observed, methods used to prepare the decay data sets for each radionuclide in the format of the computerized evaluated nuclear structure data file, the tables of radioactive decay data, and the computer code MEDLIST used to produce the tables are described. Applications of the data to problems of interest in radiation dosimetry and radiological assessments are considered as well as the calculations of the activity of a daughter radionuclide relative to the activity of its parent in a radioactive decay chain.

  2. Decay properties of high-lying single-particles modes

    Energy Technology Data Exchange (ETDEWEB)

    Beaumel, D. [Institut de Physique Nucleaire, 91 - Orsay (France); Fortier, S. [Institut de Physique Nucleaire, 91 - Orsay (France); Gales, S. [Institut de Physique Nucleaire, 91 - Orsay (France); Guillot, J. [Institut de Physique Nucleaire, 91 - Orsay (France); Langevin-Joliot, H. [Institut de Physique Nucleaire, 91 - Orsay (France); Laurent, H. [Institut de Physique Nucleaire, 91 -Orsay (France); Maison, J.M. [Institut de Physique Nucleaire, 91 - Orsay (France); Vernotte, J. [Institut de Physique Nucleaire, 91 - Orsay (France); Bordewijck, J. [Kernfysisch Versneller Instituut, 9747 Groningen (Netherlands); Brandenburg, S. [Kernfysisch Versneller Instituut, 9747 Groningen (Netherlands); Krasznahorkay, A. [Kernfysisch Versneller Instituut, 9747 Groningen (Netherlands); Crawley, G.M. [NSCL, Michigan State University, East Lansing, MI 48824 (United States); Massolo, C.P. [Universitad Nacional de La Plata, 1900 La Plata (Argentina); Renteria, M. [Universitad Nacional de La Plata, 1900 La Plata (Argentina); Khendriche, A. [University of Tizi-Ouzou, Tizi-Ouzou (Algeria)

    1996-03-18

    The neutron decay of high-lying single-particle states in {sup 64}Ni, {sup 90}Zr, {sup 120}Sn and {sup 208}Pb excited by means of the ({alpha},{sup 3}He) reaction has been investigated at 120 MeV incident energy using the multidetector EDEN. The characteristics of this reaction are studied using inclusive spectra and angular correlation analysis. The structure located between 11 and 15 MeV in {sup 91}Zr, and between 8 and 12 MeV excitation energy in {sup 209}Pb display large departures from a pure statistical decay. The corresponding non-statistical branching ratios are compared with the results of two theoretical calculations. (orig.).

  3. Measurement of B decays to phi K gamma

    Energy Technology Data Exchange (ETDEWEB)

    Aubert, B.

    2006-07-28

    We measure the branching fraction of the radiative B{sup -} decay {Beta}(B{sup -} {yields} {phi}K{sup -}{gamma}) = (3.46 {+-} 0.57{sub -0.37}{sup +0.39}) x 10{sup -6}, and set an upper limit on the radiative {bar B}{sup 0} decay {Beta}({bar B}{sup 0} {yields} {phi}{bar K}{sup 0}{gamma}) < 2.71 x 10{sup -6} at 90% confidence level. We also measure the direct CP asymmetry of the B{sup -} {yields} {phi}K{sup -}{gamma} mode {Alpha}{sub CP} = (-26.4 {+-} 14.3 {+-} 4.8)%. The uncertainties are statistical and systematic, respectively. These measurements are based on 207 fb{sup -1} of data collected at the {Upsilon}(4S) resonance with the BABAR detector.

  4. B{yields}V{gamma} decays at NNLO in SCET

    Energy Technology Data Exchange (ETDEWEB)

    Ali, A.; Pecjak, B.D. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Greub, C. [Bern Univ. (Switzerland). Inst. fuer Theoretische Physik

    2007-09-15

    We compute NNLO (O({alpha}{sup 2}{sub s})) corrections to the hard-scattering kernels entering the QCD factorization formula for B {yields} V{gamma} decays, where V is a light vector meson. We give complete NNLO results for the dipole operators Q{sub 7} and Q{sub 8}, and partial results for Q{sub 1} valid in the large-{beta}{sub 0} limit and neglecting the NNLO correction from hard spectator scattering. Large perturbative logarithms in the hard-scattering kernels are identified and resummed using soft-collinear effective theory. We use our results to estimate the branching fractions for B {yields} K{sup *}{gamma} and B{sub s} {yields} {phi}{gamma} decays at NNLO and compare them with the current experimental data. (orig.)

  5. Dark matter from late invisible decays to and of gravitinos

    Science.gov (United States)

    Allahverdi, Rouzbeh; Dutta, Bhaskar; Queiroz, Farinaldo S.; Strigari, Louis E.; Wang, Mei-Yu

    2015-03-01

    In this work, we sift a simple supersymmetric framework of late invisible decays to and of the gravitino. We study a simple extension of the minimal supersymmetric standard model that includes isosinglet color-triplet superfields and a singlet superfield. We investigate two cases where the gravitino is the lightest supersymmetric particle or the next-to-lightest supersymmetric particle. The next-to-lightest supersymmetric particle decays into two dark matter candidates and has a long lifetime due to gravitationally suppressed interactions. However, because of the absence of any hadronic or electromagnetic products, it satisfies the tight bounds set by big bang nucleosynthesis and the cosmic microwave background. One or both of the dark matter candidates produced in invisible decays can contribute to the amount of dark radiation and suppress perturbations at scales that are being probed by the galaxy power spectrum and the Lyman-alpha forest data. We show that these constraints are satisfied in large regions of the parameter space and, as a result, the late invisible decays to and of the gravitino can be responsible for the entire dark matter relic abundance.

  6. Rare KL decays at Fermilab

    International Nuclear Information System (INIS)

    Schnetzer, St.

    1997-01-01

    Recent results and the future prospects for rare K L decay at Fermilab are described. A summary of all rare decay results from E799 Phase I (the 1991 run) are presented. Three new results: K L → e + e - μ + μ - , K L → π 0 μe, and π 0 → e + e - e + e - are discussed in detail. Improvements for KTeV (the 1996-1997 run) are discussed and the expected sensitivities listed. Finally, the KAMI program for rare decays with the Main Injector (2000 and beyond) is presented with emphasis on a search for the decay K L → π 0 νν-bar at O(10 -12 ) single-event-sensitivity. (author)

  7. CP violation in K decays

    International Nuclear Information System (INIS)

    Gilman, F.J.

    1989-05-01

    Recent theoretical and experimental progress on the manifestation of CP violation in K decays, and toward understanding whether CP violation originates in a phase, or phases, in the weak mixing matrix of quarks is reviewed. 23 refs., 10 figs

  8. Data for decay Heat Predictions

    International Nuclear Information System (INIS)

    1987-01-01

    These proceedings of a specialists' meeting on data for decay heat predictions are based on fission products yields, on delayed neutrons and on comparative evaluations on evaluated and experimental data for thermal and fast fission. Fourteen conferences were analysed

  9. CP violation in B decays

    International Nuclear Information System (INIS)

    Kayser, B.

    1990-01-01

    The study of CP-violating effects in B decays will be a good test of whether CP violation is caused by the known weak interaction. If this is its origin, then large, cleanly-predicted CP-violating effects are expected in certain neutral B decays to hadronic CP eigenstates. The phenomenology of CP violation in the B system is reviewed, and the genesis of these large effects is explained. In this it is shown that large, cleanly-predicted effects are also expected in some decays to states which are not CP eigenstates. The combined study of the latter decays and those to CP eigenstates may make it possible to obtain a statistically-significant CP-violating signal with fewer B mesons that would otherwise be required

  10. Weak Decays of Charmed Particles

    Energy Technology Data Exchange (ETDEWEB)

    Turcotte, Marc Gilles [McGill Univ., Montreal, QC (Canada)

    1986-05-01

    The lifetimes of charmed particles produced in interactions of high energy neutrinos with nucleons have been measured using a combination of a very high resolution emulsion-based vertex detector and a spectrometer allowing full kinematical reconstruction of the decays.

  11. Case Study - Alpha

    Directory of Open Access Journals (Sweden)

    Stephen Leybourne

    2016-11-01

    Full Text Available This case study was developed from an actual scenario by Dr. Steve Leybourne of Boston University.  The case documents the historical evolution of an organization, and has been used successfully in courses dealing with organizational and cultural change, and the utilization of ‘soft skills’ in project-based management. This is a short case, ideal for classroom use and discussion.  The issues are easily accessible to students, and there is a single wide ranging question that allows for the inclusion of many issues surrounding strategic decision-making, and behavioural and cultural change. Alpha was one of the earlier companies in the USA to invest in large, edge-of-town superstores, with plentiful free vehicle parking, selling food and related household products. Alpha was created in the 1950s as a subsidiary of a major publicly quoted retail group.  It started business by opening a string of very large discount stores in converted industrial and warehouse premises in the south of the United States. In the early days shoppers were offered a limited range of very competitively priced products. When Alpha went public in 1981 it was the fourth largest food retailer in the US, selling an ever-widening range of food and non-food products.  Its success continued to be based on high volume, low margins and good value for money, under the slogan of ‘Alpha Price.’

  12. Alpha-mannosidosis

    DEFF Research Database (Denmark)

    Borgwardt, Line; Stensland, Hilde Monica Frostad Riise; Olsen, Klaus Juul

    2015-01-01

    of the three subgroups of genotype/subcellular localisation and the clinical and biochemical data were done to investigate the potential relationship between genotype and phenotype in alpha-mannosidosis. Statistical analyses were performed using the SPSS software. Analyses of covariance were performed...

  13. Parametric decay of the curvaton

    International Nuclear Information System (INIS)

    Enqvist, K; Nurmi, S; Rigopoulos, G I

    2008-01-01

    We argue that the curvaton decay takes place most naturally by way of a broad parametric resonance. The mechanism is analogous to resonant inflaton decay but does not require any tuning of the curvaton coupling strength to other scalar fields. For low scale inflation and a correspondingly low mass scale for the curvaton, we speculate on observable consequences including the possibility of stochastic gravitational waves

  14. Strange decays from strange resonances

    Energy Technology Data Exchange (ETDEWEB)

    Bijker, R. [Instituto de Ciencias Nucleares, Universidad Nacional Autonoma de Mexico, A.P. 70-543, 04510 Mexico D.F. (Mexico); Leviatan, A. [Racah Institute of Physics, The Hebrew University, Jerusalem 91904 (Israel)

    2001-07-01

    We discuss the mass spectrum and strong decays of baryon resonances belonging to the N, {delta}, {sigma}, {lambda}, {xi} and {omega} families in a collective string- like model for the nucleon. We find good overall agreement with the available data. Systematic discrepancies are found for low-lying S-wave states, in particular in the strong decays of N(1535), N(1650), {sigma}(1750), {lambda}{sup *}(1405), {lambda}(1670) and {lambda}(1800). (Author)

  15. Strange decays from strange resonances

    International Nuclear Information System (INIS)

    Bijker, R.; Leviatan, A.

    2001-01-01

    We discuss the mass spectrum and strong decays of baryon resonances belonging to the N, Δ, Σ, Λ, Ξ and Ω families in a collective string- like model for the nucleon. We find good overall agreement with the available data. Systematic discrepancies are found for low-lying S-wave states, in particular in the strong decays of N(1535), N(1650), Σ(1750), Λ * (1405), Λ(1670) and Λ(1800). (Author)

  16. Polarization bremsstrahlung in α decay

    International Nuclear Information System (INIS)

    Amusia, M. Ya.; Zon, B. A.; Kretinin, I. Yu.

    2007-01-01

    A mechanism of formation of electromagnetic radiation that accompanies α decay and is associated with the emission of photons by electrons of atomic shells due to the scattering of α particles by these atoms (polarization bremsstrahlung) is proposed. It is shown that, when the photon energy is no higher than the energy of K electrons of an atom, polarization bremsstrahlung makes a significant contribution to the bremsstrahlung in α decay

  17. Alpha and conversion electron spectroscopy of 238,239Pu and 241Am and alpha-conversion electron coincidence measurements

    Energy Technology Data Exchange (ETDEWEB)

    Dion, Michael P.; Miller, Brian W.; Warren, Glen A.

    2016-09-01

    A technique to determine the isotopics of a mixed actinide sample has been proposed by measuring the coincidence of the alpha particle during radioactive decay with the conversion electron (or Auger) emitted during the relaxation of the daughter isotope. This presents a unique signature to allow the deconvolution of isotopes that possess overlapping alpha particle energy. The work presented here are results of conversion electron spectroscopy of 241Am, 238Pu and 239Pu using a dual-stage peltier-cooled 25 mm2 silicon drift detector. A passivated ion implanted planar silicon detector provided measurements of alpha spectroscopy. The conversion electron spectra were evaluated from 20–55 keV based on fits to the dominant conversion electron emissions, which allowed the relative conversion electron emission intensities to be determined. These measurements provide crucial singles spectral information to aid in the coincident measurement approach.

  18. Higgs boson decay into b-quarks at NNLO accuracy

    CERN Document Server

    Del Duca, Vittorio; Somogyi, Gábor; Tramontano, Francesco; Trócsányi, Zoltán

    2015-01-01

    We compute the fully differential decay rate of the Standard Model Higgs boson into b-quarks at next-to-next-to-leading order (NNLO) accuracy in alpha_S. We employ a general subtraction scheme developed for the calculation of higher order perturbative corrections to QCD jet cross sections, which is based on the universal infrared factorization properties of QCD squared matrix elements. We show that the subtractions render the various contributions to the NNLO correction finite. In particular, we demonstrate analytically that the sum of integrated subtraction terms correctly reproduces the infrared poles of the two-loop double virtual contribution to this process. We present illustrative differential distributions obtained by implementing the method in a parton level Monte Carlo program. The basic ingredients of our subtraction scheme, used here for the first time to compute a physical observable, are universal and can be employed for the computation of more involved processes.

  19. Chains and identity

    NARCIS (Netherlands)

    Grijpink, J.H.A.M.

    2012-01-01

    This article is available in English and DutchGuidelines are presented to cope with identity problems in chains. A chain is a collaboration of a great number of autonomous organisations and professionals to tackle a dominant chain problem. In many chains identity fraud is an aspect of the dominant

  20. Silicone chain extender

    DEFF Research Database (Denmark)

    2015-01-01

    The present invention relates to a silicone chain extender, more particularly a chain extender for silicone polymers and copolymers, to a chain extended silicone polymer or copolymer and to a functionalized chain extended silicone polymer or copolymer, to a method for the preparation thereof...

  1. Logistic chain modelling

    NARCIS (Netherlands)

    Slats, P.A.; Bhola, B.; Evers, J.J.M.; Dijkhuizen, G.

    1995-01-01

    Logistic chain modelling is very important in improving the overall performance of the total logistic chain. Logistic models provide support for a large range of applications, such as analysing bottlenecks, improving customer service, configuring new logistic chains and adapting existing chains to

  2. ZZ NUCDECAYCALC, Nuclear Decay Data for Radiation Dosimetry Calculation for ICRP

    International Nuclear Information System (INIS)

    2002-01-01

    1 - Description or function: The Dosimetry Research Group (DRG) of the Health Sciences Research Division at ORNL has for several years maintained data bases of nuclear decay data for use in dosimetric calculations. The data on mean and unique energy plus intensity have been previously published, in abridged form, in Publication 38 of the International Commission on Radiological Protection (ICRP 1983). This data base was designed to address the needs in medical, environmental, and occupational radiation protection. DLC-172/NUCDECAY is required by the CCC-620/SEECAL program to calculate age-dependent specific effective energies. 2 - Methods: The unabridged data used in preparing ICRP Publication 38 are distributed in electronic form in this package. The collection consists of data on the energies and intensities of radiations emitted by the 825 radionuclides reported, although abridged, in ICRP Publication 38 plus an additional 13 radionuclides evaluated during preparation of a monograph for the Medical Internal Radiation Dose (MIRD) Committee of the Society of Nuclear Medicine. Each collection is contained in an ASCII file (INDEXR.DAT) which is a sorted list of the radionuclides containing the decay chain information. The utility code DecayCalc extracts the decay data from the library for radionuclide(s) specified by the user. It computes the activities of radionuclides present after decay and ingrowth over a user-specified time period from 1 minute to 50 years. Decay data for any decay chain may be displayed and printed either in tabular form or graphically. DecayCalc, in a slightly modified version, will be a part of CCC-553/Rascal v3. DecayCalc is a Windows application that runs under Microsoft Windows 95 or 98, or Microsoft Windows NT 4.0 or later. The Compac Fortran 77 compiler was used to compile the code. The full source for DecayCalc is not provided but will be distributed when Rascal V3 is released

  3. Demystifying AlphaGo Zero as AlphaGo GAN

    OpenAIRE

    Dong, Xiao; Wu, Jiasong; Zhou, Ling

    2017-01-01

    The astonishing success of AlphaGo Zero\\cite{Silver_AlphaGo} invokes a worldwide discussion of the future of our human society with a mixed mood of hope, anxiousness, excitement and fear. We try to dymystify AlphaGo Zero by a qualitative analysis to indicate that AlphaGo Zero can be understood as a specially structured GAN system which is expected to possess an inherent good convergence property. Thus we deduct the success of AlphaGo Zero may not be a sign of a new generation of AI.

  4. Electronic properties of linear carbon chains: Resolving the controversy

    Science.gov (United States)

    Al-Backri, Amaal; Zólyomi, Viktor; Lambert, Colin J.

    2014-03-01

    Literature values for the energy gap of long one-dimensional carbon chains vary from as little as 0.2 eV to more than 4 eV. To resolve this discrepancy, we use the GW many-body approach to calculate the band gap Eg of an infinite carbon chain. We also compute the energy dependence of the attenuation coefficient β governing the decay with chain length of the electrical conductance of long chains and compare this with recent experimental measurements of the single-molecule conductance of end-capped carbon chains. For long chains, we find Eg = 2.16 eV and an upper bound for β of 0.21 Å-1.

  5. Electronic properties of linear carbon chains: Resolving the controversy

    International Nuclear Information System (INIS)

    Al-Backri, Amaal; Zólyomi, Viktor; Lambert, Colin J.

    2014-01-01

    Literature values for the energy gap of long one-dimensional carbon chains vary from as little as 0.2 eV to more than 4 eV. To resolve this discrepancy, we use the GW many-body approach to calculate the band gap E g of an infinite carbon chain. We also compute the energy dependence of the attenuation coefficient β governing the decay with chain length of the electrical conductance of long chains and compare this with recent experimental measurements of the single-molecule conductance of end-capped carbon chains. For long chains, we find E g = 2.16 eV and an upper bound for β of 0.21 Å −1

  6. $\\alpha$-Representation for QCD

    OpenAIRE

    Tuan, Richard Hong

    1998-01-01

    An $\\alpha$-parameter representation is derived for gauge field theories.It involves, relative to a scalar field theory, only constants and derivatives with respect to the $\\alpha$-parameters. Simple rules are given to obtain the $\\alpha$-representation for a Feynman graph with an arbitrary number of loops in gauge theories in the Feynman gauge.

  7. Alpha Theta Meditation: Phenomenological, neurophysiologic ...

    African Journals Online (AJOL)

    Alpha Theta Meditation: Phenomenological, neurophysiologic, mindfulness, mood, health and sport implications. ... the single alpha theta meditation was associated with elevated alpha and theta activity, as well as decrease in negative mood perceptions, especially with regard to anxiety, sadness and confusion scores.

  8. Extrasynaptic location of laminin beta 2 chain in developing and adult human skeletal muscle

    DEFF Research Database (Denmark)

    Wewer, U M; Thornell, L E; Loechel, F

    1997-01-01

    and Becker muscular dystrophy. Immunoaffinity chromatography of muscle extracts with a monoclonal antibody to the laminin alpha 2 chain followed by immunoblotting with various antibodies to the beta 2 chain demonstrated the presence of the laminin-4 (alpha 2-beta 2-gamma 1) isoform. Together the present...... myofibers. In the adult skeletal muscle, laminin beta 2 chain immunoreactivity was found along the entire perimeter of each of the individual myofibers in a large series of different muscles studied. Laminin beta 2 chain was similarly found in the skeletal muscle basement membranes in patients with Duchenne...

  9. Structural and functional studies of hemoglobin Moabit (alpha 86(F7) Leu-->Arg.

    Science.gov (United States)

    Gulbis, B; Tshilolo, L; Wajcman, H; Riou, J; Galactéros, F; Promé, D; Kister, J; Papassotiriou, I; Van Laethem, Y; Vertongen, F

    1997-06-01

    An abnormal hemoglobin fraction was detected on high performance liquid chromatography profile performed for the measurement of glycated hemoglobin in a 55-year-old caucasian patient. The structural and functional studies were performed by standard techniques. Separation of hemoglobins by alkaline electrophoresis and by IEF revealed a slightly more rapid fraction than does Hb S. By acid electrophoresis, no abnormal Hb fraction could be observed. Separation of globin chains by electrophoresis demonstrated an alpha-chain variant and by chromatography, a fraction which eluted between beta and gamma globin chains. Tryptic digests and amino acid analysis have demonstrated a previously described substitution of Leu-->Arg alpha 86(F7).

  10. In-trap decay spectroscopy for {beta}{beta} decays

    Energy Technology Data Exchange (ETDEWEB)

    Brunner, Thomas

    2011-01-18

    The presented work describes the implementation of a new technique to measure electron-capture (EC) branching ratios (BRs) of intermediate nuclei in {beta}{beta} decays. This technique has been developed at TRIUMF in Vancouver, Canada. It facilitates one of TRIUMF's Ion Traps for Atomic and Nuclear science (TITAN), the Electron Beam Ion Trap (EBIT) that is used as a spectroscopy Penning trap. Radioactive ions, produced at the radioactive isotope facility ISAC, are injected and stored in the spectroscopy Penning trap while their decays are observed. A key feature of this technique is the use of a strong magnetic field, required for trapping. It radially confines electrons from {beta} decays along the trap axis while X-rays, following an EC, are emitted isotropically. This provides spatial separation of X-ray and {beta} detection with almost no {beta}-induced background at the X-ray detector, allowing weak EC branches to be measured. Furthermore, the combination of several traps allows one to isobarically clean the sample prior to the in-trap decay spectroscopy measurement. This technique has been developed to measure ECBRs of transition nuclei in {beta}{beta} decays. Detailed knowledge of these electron capture branches is crucial for a better understanding of the underlying nuclear physics in {beta}{beta} decays. These branches are typically of the order of 10{sup -5} and therefore difficult to measure. Conventional measurements suffer from isobaric contamination and a dominating {beta} background at theX-ray detector. Additionally, X-rays are attenuated by the material where the radioactive sample is implanted. To overcome these limitations, the technique of in-trap decay spectroscopy has been developed. In this work, the EBIT was connected to the TITAN beam line and has been commissioned. Using the developed beam diagnostics, ions were injected into the Penning trap and systematic studies on injection and storage optimization were performed. Furthermore, Ge

  11. Alpha scintillation radon counting

    International Nuclear Information System (INIS)

    Lucas, H.F. Jr.

    1977-01-01

    Radon counting chambers which utilize the alpha-scintillation properties of silver activated zinc sulfide are simple to construct, have a high efficiency, and, with proper design, may be relatively insensitive to variations in the pressure or purity of the counter filling. Chambers which were constructed from glass, metal, or plastic in a wide variety of shapes and sizes were evaluated for the accuracy and the precision of the radon counting. The principles affecting the alpha-scintillation radon counting chamber design and an analytic system suitable for a large scale study of the 222 Rn and 226 Ra content of either air or other environmental samples are described. Particular note is taken of those factors which affect the accuracy and the precision of the method for monitoring radioactivity around uranium mines

  12. Summary report of RAMONA investigations into passive decay heat removal

    International Nuclear Information System (INIS)

    Hoffmann, H.; Marten, K.; Weinberg, D.; Frey, H.H.; Rust, K.; Ieda, Y.; Kamide, H.; Ohshima, H.; Ohira, H.

    1995-07-01

    An important safety feature of an advanced sodium-cooled reactor (e.g. European Fast Reactor, EFR) is the passive decay heat removal. This passive concept is based on several direct reactor cooling systems operating independently from each other. Each of the systems consists of a sodium/sodium decay heat exchanger immersed in the primary vessel and connected via an intermediate sodium loop to a heat sink formed by a sodium/air heat exchanger installed in a stack with air inlet and outlet dampers. The decay heat is removed by natural convection on the sodium side and natural draft on the air side. To demonstrate the coolability of the pool-type primary system by buoyancy-driven natural circulation, tests were performed under steady-state and transient conditions in facilities of different scale and detail. All these investigations serve to understand the physical processes and to verify computer codes used to transfer the results to reactor conditions. RAMONA is the three-dimensional 1:20-scaled apparatus equipped with all active components. Water is used as simulant fluid for sodium. The maximum core power is 75 kW. The facility is equipped with about 250 thermocouples to register fluid temperatures. Velocities and mass flows are measured by Laser Doppler Anemometers and magneto-inductive flowmeters. Flow paths are visualized by tracers. The conclusion of the investigations is that the decay heat can be removed from the primary system by means of natural convection. Always flow paths develop, which ensure an effective cooling of all regions. This is even proved for extreme conditions, e.g. in case of delays of the decay heat exchanger startup, failures of several DHR chains, and a drop of the fluid level below the inlet windows of the IHXs and decay heat exchangers. (orig.) [de

  13. Sustainable Supply Chain Design

    DEFF Research Database (Denmark)

    Bals, Lydia; Tate, Wendy

    A significant conceptual and practical challenge is how to integrate triple bottom line (TBL; including economic, social and environmental) sustainability into global supply chains. Although this integration is necessary to slow down global resource depletion, understanding is limited of how...... to implement TBL goals across the supply chain. In supply chain design, the classic economic perspective still dominates, although the idea of the TBL is more widely disseminated. The purpose of this research is to add to the sustainable supply chain management literature (SSCM) research agenda...... by incorporating the physical chain, and the (information and financial) support chains into supply chain design. This manuscript tackles issues of what the chains are designed for and how they are designed structurally. Four sustainable businesses are used as illustrative case examples of innovative supply chain...

  14. Evaluating Reverse Supply Chain Efficiency: Manufacturer's Perspective

    DEFF Research Database (Denmark)

    Kumar, M.; Tiwari, M. K.; Wong, K. Y.

    2014-01-01

    The paper aims to illustrate the use of fuzzy data envelopment analysis (DEA) in analyzing reverse supply chain (RSC) performance from the manufacturer's perspective. By using an alternative alpha-cut approach, the fuzzy DEA model was converted into a crisp linear programming problem, thereby...... altering the problem to an interval programming one. The model is able to obtain precise and robust efficiency values. An investigation was also made between the obtained efficiency scores and certain relevant background information of the companies. The study revealed that while ISO 14001 certification...... usually ensures an environmentally friendly supply chain network, companies which have implemented RSC techniques since a longer duration do not necessarily have a more efficient supply chain in general....

  15. Combining Alphas via Bounded Regression

    Directory of Open Access Journals (Sweden)

    Zura Kakushadze

    2015-11-01

    Full Text Available We give an explicit algorithm and source code for combining alpha streams via bounded regression. In practical applications, typically, there is insufficient history to compute a sample covariance matrix (SCM for a large number of alphas. To compute alpha allocation weights, one then resorts to (weighted regression over SCM principal components. Regression often produces alpha weights with insufficient diversification and/or skewed distribution against, e.g., turnover. This can be rectified by imposing bounds on alpha weights within the regression procedure. Bounded regression can also be applied to stock and other asset portfolio construction. We discuss illustrative examples.

  16. Stability of 244− 260Fm isotopes against alpha and cluster ...

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 73; Issue 6. Stability of 244-260Fm isotopes against alpha and cluster radioactivity. K P Santhosh ... Taking Coulomb and proximity potentials as the interacting barrier we have studied the cold valley in the radioactive decay of 244-260Fm isotopes. It is found that in ...

  17. Aerosol properties of indoor radon decay products

    International Nuclear Information System (INIS)

    Martell, E.A.

    1984-01-01

    Lung cancer risks attributable to indoor radon are highly dependent on the properties of radon progeny aerosols which, in turn, are dependent on the nature and concentration of small particles in indoor air. In clean filtered air, radon progeny are attached to small hygroscopic particles of high mobility which are rapidly deposited on surfaces. By contrast, radon progeny attached to cigarette smoke are on large particles of low mobility which persist in air. Radon progeny ingaled by smokers are largely associated with smoke particles from 0.5 to 4.0 μm diameter. Such particles are selectively deposited at bronchial bifurcations and are highly resistant to dissolution. The attached radon progeny undergo a substantial degree of radioactive decay at deposition sites before clearance which gives rise to large alpha radiation doses in small volumes of bronchial epithelium. These processes provide new insights on mechanisms of bronchial cancer induction and on relative risks of lung cancer in smokers, passive smokers, and other non-smokers. (Author)

  18. Alpha detection as a probe for counter proliferation

    Energy Technology Data Exchange (ETDEWEB)

    Koster, J.E.; Johnson, J.P.; MacArthur, D.W.; Walters, S.G.

    1994-07-01

    An indication of the presence of special nuclear material (SNM) can be obtained by the detection of alpha particles from the decay of the SNM. Current techniques for detecting alpha particles have a number of limitations. Sensitive conventional detection of SNM traces involves off-site laboratory analysis -- but at the loss of an on-site confirmation. Fieldable detection instruments, on the other hand, are delicate and have poor sensitivity. New long-range alpha detection (LRAD) technology mitigates these limitations. An LRAD-based instrument relies on the detection of the hundreds of thousands of ions produced in ambient air by one emitted alpha particle. The ions can be transported to an ion detector at a distance much greater than the range of the original alpha particle. The LRAD-based monitors have the characteristics of high sensitivity, fast (real-time) response, ruggedness, and reliability. Many of the designs are quite portable. In this paper, several scenarios are identified for which particular LRAD-based detectors can provide confirmation of proliferation activity.

  19. Decay spectroscopy of $^{178}$Au

    CERN Document Server

    Whitmore, B

    In this thesis, the neutron-deficient nucleus $^{178}$Au is investigated through decay spectroscopy. Si and HPGe detectors were used to analyse the decay radiation of $^{178}$Au and its daughter nuclei. Previous studies have been unable to distinguish decay radiation from different isomeric states of this nucleus. This thesis represents the first time such isomeric discrimination has been achieved, and presents tentative spin assignments of both the ground state and an isomer. The neutron-deficient gold isotopes are an area of interest for the study of shape coexistence. This is the phenomenon exhibited by nuclei able to exist at a number of close lying energy minima, each reflecting a distinct type of deformation. It is hoped that studies such as this can help identify the evolution of nuclear deformation in this region of the nuclear chart.

  20. Rare decay searches at CDF

    Energy Technology Data Exchange (ETDEWEB)

    Maestro, Paolo [Siena U.

    2012-07-01

    In the last decade the CDF experiment at the Tevatron clearly demonstrated that it is possible to study extensively heavy flavour physics in hadron collisions and achieve remarkable results, competitive and complementary to $B$-factories. In this paper we report on the indirect searches for physics beyond the standard model via measurements of rare $b$-hadron decays. The final limits, based on the analysis of the full CDF data set, on the branching fraction of the $B^0_{(s)}$ decay into a pair of muons are presented and discussed. Moreover we review the latest measurements, with 6.8 fb$^{-1}$ of collected data, of the total and differential branching fractions and angular observables of rare $b$-hadron decays proceeding via the flavour-changing neutral-current process $b \\rightarrow s \\mu^+ \\mu^-$. PACS numbers: 13.20.He, 13.30.-a, 12.15.Mn