WorldWideScience

Sample records for air toxics information

  1. Comparing toxic air pollutant programs

    Energy Technology Data Exchange (ETDEWEB)

    Hawkins, S.C. [ECKENFELDER Inc., Greenville, SC (United States)

    1997-05-01

    This article compares state and federal toxic air pollutant programs. The Clean Air Act Ammendments created a program for the control of Hazardous Air Pollutants based on the establishment of control technology standards. State toxic programs can be classified into two categories: control technology-based and ambient concentration-based. Many states have opened to implement the MACT standards while enforcing their own state air toxics programs. Specific topics discussed include the following: the Federal air toxics program; existing state regulations; New Jersey Air Toxic Program; New York Toxics program.

  2. Exposure information in environmental health research: Current opportunities and future directions for particulate matter, ozone, and toxic air pollutants

    Energy Technology Data Exchange (ETDEWEB)

    McKone, Thomas E.; Ryan, P. Barry; Ozkaynak, Haluk

    2007-02-01

    Understanding and quantifying outdoor and indoor sources of human exposure are essential but often not adequately addressed in health-effects studies for air pollution. Air pollution epidemiology, risk assessment, health tracking and accountability assessments are examples of health-effects studies that require but often lack adequate exposure information. Recent advances in exposure modeling along with better information on time-activity and exposure factors data provide us with unique opportunities to improve the assignment of exposures for both future and ongoing studies linking air pollution to health impacts. In September 2006, scientists from the US Environmental Protection Agency (EPA) and the Centers for Disease Control and Prevention (CDC) along with scientists from the academic community and state health departments convened a symposium on air pollution exposure and health in order to identify, evaluate, and improve current approaches for linking air pollution exposures to disease. This manuscript presents the key issues, challenges and recommendations identified by the exposure working group, who used cases studies of particulate matter, ozone, and toxic air pollutant exposure to evaluate health-effects for air pollution. One of the over-arching lessons of this workshop is that obtaining better exposure information for these different health-effects studies requires both goal-setting for what is needed and mapping out the transition pathway from current capabilities to meeting these goals. Meeting our long-term goals requires definition of incremental steps that provide useful information for the interim and move us toward our long-term goals. Another over-arching theme among the three different pollutants and the different health study approaches is the need for integration among alternate exposure assessment approaches. For example, different groups may advocate exposure indicators, biomonitoring, mapping methods (GIS), modeling, environmental media

  3. National Air Toxic Assessments (NATA) Results

    Data.gov (United States)

    U.S. Environmental Protection Agency — The National Air Toxics Assessment was conducted by EPA in 2002 to assess air toxics emissions in order to identify and prioritize air toxics, emission source types...

  4. 2011 NATA - Air Toxics Monitors

    Data.gov (United States)

    U.S. Environmental Protection Agency — This dataset includes annual (2005 - 2013) statistics of measured ambient air toxics concentrations (in micrograms per cubic meter) and associated risk estimates for...

  5. Air Risk Information Support Center

    Energy Technology Data Exchange (ETDEWEB)

    Shoaf, C.R.; Guth, D.J. [Environmental Protection Agency, Washington, DC (United States)

    1990-12-31

    The Air Risk Information Support Center (Air RISC) was initiated in early 1988 by the US Environmental Protection Agency`s (EPA) Office of Health and Environmental Assessment (OHEA) and the Office of Air Quality Planning and Standards (OAQPS) as a technology transfer effort that would focus on providing information to state and local environmental agencies and to EPA Regional Offices in the areas of health, risk, and exposure assessment for toxic air pollutants. Technical information is fostered and disseminated by Air RISCs three primary activities: (1) a {open_quotes}hotline{close_quotes}, (2) quick turn-around technical assistance projects, and (3) general technical guidance projects. 1 ref., 2 figs.

  6. Environmental air toxics: role in asthma occurrence?

    OpenAIRE

    Larsen, Gary L.; Beskid, Craig; Shirnamé-Moré, Lata

    2002-01-01

    The National Urban Air Toxics Research Center (NUATRC) hosted its first scientific workshop in 1994 that focused on possible relationships between air toxics and asthma. From that meeting came recommendations for future research including a need for more complete individual personal exposure assessments so that determinations of personal exposures to pollutants could be made. In the spring of 2001, NUATRC held a second such workshop to review progress made in this area during the intervening ...

  7. AIR TOXICS MODELING RESEARCH PROGRAM: AN OVERVIEW

    Science.gov (United States)

    This product is a Microsoft Powerpoint slide presentation which was given at the joint EPA Region 3 - Mid-Atlantic Regional Air Management Association (MARAMA) Air Toxic Summit in Philadelphia, Pennsylvania held from October 18, 2005 through October 20, 2005. The slide presentat...

  8. Air toxics and asthma: Impacts and end points

    Energy Technology Data Exchange (ETDEWEB)

    Eschenbacher, W.L.; Holian, A.; Campion, R.J. [Mickey Leland National urban Air Toxics Research Center, Houston, TX (United States)

    1995-09-01

    The National Urban Air Toxics Research Center (NUATRC) hosted a medical/scientific workshop (February 1994) focused on possible asthma/air toxics relationships, with the results of the NUATRC`s first research contract with the University of Cincinnati as the point of discussion. The workshop explored the impact of various environmental factors, including air toxics, on asthma incidence and exacerbation; and emphasis was placed on future research directions. The information presented at the workshop suggested a possible association of asthma exacerbations with ozone and particulate matter (PM{sub 10}); however, direct relationships between worsening asthma and air toxic ambient levels were not established. Possible respiratory health effects associated with air toxics will require considerably more investigation, especially in the area of human exposure assessment. Two major recommendations for future research resulted form this workshop and an accompanying NUATRC Scientific Advisory Panel meeting: a need for more complete individual personal exposure assessments so that accurate determinations of actual personal exposures to various pollutants can be made; and a need for field experiments utilizing biomarkers of exposure and effect to more accurately assess the extent and variability of the biological effects, if any, of individual air toxics. 8 refs.

  9. Air System Information Management

    Science.gov (United States)

    Filman, Robert E.

    2004-01-01

    I flew to Washington last week, a trip rich in distributed information management. Buying tickets, at the gate, in flight, landing and at the baggage claim, myriad messages about my reservation, the weather, our flight plans, gates, bags and so forth flew among a variety of travel agency, airline and Federal Aviation Administration (FAA) computers and personnel. By and large, each kind of information ran on a particular application, often specialized to own data formats and communications network. I went to Washington to attend an FAA meeting on System-Wide Information Management (SWIM) for the National Airspace System (NAS) (http://www.nasarchitecture.faa.gov/Tutorials/NAS101.cfm). NAS (and its information infrastructure, SWIM) is an attempt to bring greater regularity, efficiency and uniformity to the collection of stovepipe applications now used to manage air traffic. Current systems hold information about flight plans, flight trajectories, weather, air turbulence, current and forecast weather, radar summaries, hazardous condition warnings, airport and airspace capacity constraints, temporary flight restrictions, and so forth. Information moving among these stovepipe systems is usually mediated by people (for example, air traffic controllers) or single-purpose applications. People, whose intelligence is critical for difficult tasks and unusual circumstances, are not as efficient as computers for tasks that can be automated. Better information sharing can lead to higher system capacity, more efficient utilization and safer operations. Better information sharing through greater automation is possible though not necessarily easy.

  10. Air toxics emissions from an IGCC process

    Energy Technology Data Exchange (ETDEWEB)

    Mojtahedi, W.; Norrbacka, P. [Enviropower Inc., Espoo (Finland); Hinderson, A. [Vattenfall (Sweden); Rosenberg, R.; Zilliacus, R.; Kurkela, E.; Nieminen, M. [VTT Energy, Espoo (Finland); Hoffren, H. [IVO International Oy, Vantaa (Finland)

    1996-12-01

    The so-called simplified coal gasification combined cycle process, incorporating air gasification and hot gas cleanup, promises high power generation efficiency in an environmentally acceptable manner. Increasingly more stringent environmental regulations have focused attention on the emissions of not only SO{sub 2} and NO{sub x} but also on the so-called air toxics which include a number of toxic trace elements. As result of recent amendments to the United States Clean Air Act, IGCC emissions of eleven trace elements: antimony, arsenic, beryllium, cadmium, chromium, cobalt, lead, manganese, mercury, nickel, selenium - as well as the radionuclides uranium and thorium may be regulated. Similarly, air missions standards in Europe include a limit of 0.05 mg Nm{sup 3} for mercury and cadmium and 1.0 3/Nm{sup 3} for other class I trace elements. A suitable sampling/measuring system has been developed in this project (in cooperation with Imatran Voima Oy, Electric Power Research Institute (EPRI) and Radian Cooperation) which will be used in the pressurized gasification tests. This will enable an accurate measurement of the volatilized trace element species, at high temperature and pressure, which may be found in the vapour phase. Models are being developed that can be used to determine not only the chemical equilibrium composition of gaseous, liquid and solid phases, but also possible interactions of the gaseous species with aerosol particles and surfaces, These should be used to more accurately assess the impact of the toxic trace metals emitted from the simplified IGCC system

  11. A comparison of PAMS and air toxics measurements

    Science.gov (United States)

    Sistla, Gopal; Aleksic, Nenad

    One of the requirements of the 1990 Clean Air Act Amendments (CAA) is that 1-h ozone nonattainment areas that are classified severe or higher category are required to operate a network of photochemical assessment monitors (PAMS) to provide hourly measurements of volatile organic compounds (VOCs) comprising of Carbon number PAMS are 24-h-integrated canister and cartridge-based measurements of selected air toxic compounds, thereby providing an opportunity for inter-comparison and validation of both sets of data. In this study, we report such a comparison and estimates of trend for benzene, m-, p- and o-xylene, toluene, ethylbenzene, 1,2,4-trimethylbenzene, formaldehyde and acetaldehyde at Bronx, NY. The analysis shows that hourly PAMS and 24-h-integrated air toxics are in good agreement with each other exhibiting similar trends and that the PAMS with the higher temporal resolution offers information on excursions of the toxic compounds that would be quite useful in assessment of acute health effects. These findings were also found to be applicable to other locations such as South De Kalb, GA; Gary, IN and Lynn, MA.

  12. Controlling air toxics through advanced coal preparation

    Energy Technology Data Exchange (ETDEWEB)

    Straszheim, W.E.; Buttermore, W.H.; Pollard, J.L. [Iowa State Univ., Ames, IA (United States)

    1995-11-01

    This project involves the assessment of advanced coal preparation methods for removing trace elements from coal to reduce the potential for air toxic emissions upon combustion. Scanning electron microscopy-based automated image analysis (SEM-AIA) and advanced washability analyses are being applied with state-of-the-art analytical procedures to predict the removal of elements of concern by advanced column flotation and to confirm the effectiveness of preparation on the quality of quantity of clean coal produced. Specific objectives are to maintain an acceptable recovery of combustible product, while improving the rejection of mineral-associated trace elements. Current work has focused on determining conditions for controlling column flotation system across its operating range and on selection and analysis of samples for determining trace element cleanability.

  13. [Toxic fungi in Buenos Aires City and surroundings].

    Science.gov (United States)

    Romano, Gonzalo M; Iannone, Leopoldo; Novas, María V; Carmarán, Cecilia; Romero, Andrea I; López, Silvia E; Lechner, Bernardo E

    2013-01-01

    In Facultad de Ciencias Exactas y Naturales,Universidad de Buenos Aires there is a service called Servicio de Identificación de Hongos Tóxicos, directed by researchers of the Program of Medicinal Plants and Fungi Involved in Biological Degradation (PROPLAME-PRHIDEB, CONICET) that assist hospitals and other health establishments, identifying the different samples of fungi and providing information about their toxicity, so that patients can receive the correct treatment. The objective of the present study was to analyze all the cases received from 1985 to 2012. This analysis permitted the confection of a table identifying the most common toxic species. The information gathered revealed that 47% of the patients were under 18 years of age and had eaten basidiomes; the remaining 53% were adults who insisted that they were able to distinguish edible from toxic mushrooms. Chlorophyllum molybdites turned out to be the main cause of fungal intoxication in Buenos Aires, which is commonly confused with Macrolepiota procera, an edible mushroom. In the second place Amanita phalloides was registered, an agaric known to cause severe symptoms after a long period of latency (6-10 hours), and which can lead to hepatic failure even requiring a transplant to prevent severe internal injuries or even death, is not early and correctly treated.

  14. Air toxics emission from an IGCC process

    Energy Technology Data Exchange (ETDEWEB)

    Mojtahedi, W.; Hovath, A. [Carbona Inc, Helsinki (Finland); Hinderson, A. [Vattenfall Utveckling (Sweden); Nykaenen, J.; Hoffren, H. [Imatran Voima Oy, Vantaa (Finland); Nieminen, M.; Kurkela, E. [VTT, Espoo (Finland)

    1997-10-01

    The emissions of 12 toxic trace element from a coal-fired IGCC plant were calculated based on thermodynamic equilibrium in the gas phase and some of the results published. The theoretical calculations were extended to include some other fuels as well as mixture of some of these fuels. The combustion of the product gas in the gas turbine is also considered. These simulations correspond to gasification of the fuel at 850-1050 deg C (depending on the fuel) and 1823 bar pressure. The gas composition was taken from the measured data as far as possible. In the absence of experimental data, a computer code developed for the U-Gas gasifier was used to determine the fuel gas composition. The gas was then cooled to 550 deg C in the gas cooler and filtered at this same temperature and burned in the gas turbine with an air ratio of 3.2. The results of these simulations are compared with the measured data of an experimental program designed to measure the emissions of a few selected trace elements from a 15 MW,h pressurized fluidized bed gasification pilot plant. The pilot plant was equipped with an advanced hot gas cleanup train which includes a two fluidized-bed reactor system for high-temperature, high-pressure external sulfur removal and a filtration unit housing porous, rigid ceramic candle filters. The trace element concentrations in the fuel, bottom ash, and filter ash are determined and the results compared with EPA regulatory levels

  15. Air toxics provisions of the Clean Air Act: Potential impacts on energy

    Energy Technology Data Exchange (ETDEWEB)

    Hootman, H.A.; Vernet, J.E.

    1991-11-01

    This report provides an overview of the provisions of the Clean Air Act and its Amendments of 1990 that identify hazardous air pollutant (HAP) emissions and addresses their regulation by the US Environmental Protection Agency (EPA). It defines the major energy sector sources of these HAPs that would be affected by the regulations. Attention is focused on regulations that would cover coke oven emissions; chromium emission from industrial cooling towers and the electroplating process; HAP emissions from tank vessels, asbestos-related activities, organic solvent use, and ethylene oxide sterilization; and emissions of air toxics from municipal waste combustors. The possible implications of Title III regulations for the coal, natural gas, petroleum, uranium, and electric utility industries are examined. The report discusses five major databases of HAP emissions: (1) TRI (EPA's Toxic Release Inventory); (2) PISCES (Power Plant Integrated Systems: Chemical Emissions Studies developed by the Electric Power Research Institute); (3) 1985 Emissions Inventory on volatile organic compounds (used for the National Acid Precipitation Assessment Program); (4) Particulate Matter Species Manual (EPA); and (5) Toxics Emission Inventory (National Aeronautics and Space Administration). It also offers information on emission control technologies for municipal waste combustors.

  16. Air toxics provisions of the Clean Air Act: Potential impacts on energy

    Energy Technology Data Exchange (ETDEWEB)

    Hootman, H.A.; Vernet, J.E.

    1991-11-01

    This report provides an overview of the provisions of the Clean Air Act and its Amendments of 1990 that identify hazardous air pollutant (HAP) emissions and addresses their regulation by the US Environmental Protection Agency (EPA). It defines the major energy sector sources of these HAPs that would be affected by the regulations. Attention is focused on regulations that would cover coke oven emissions; chromium emission from industrial cooling towers and the electroplating process; HAP emissions from tank vessels, asbestos-related activities, organic solvent use, and ethylene oxide sterilization; and emissions of air toxics from municipal waste combustors. The possible implications of Title III regulations for the coal, natural gas, petroleum, uranium, and electric utility industries are examined. The report discusses five major databases of HAP emissions: (1) TRI (EPA`s Toxic Release Inventory); (2) PISCES (Power Plant Integrated Systems: Chemical Emissions Studies developed by the Electric Power Research Institute); (3) 1985 Emissions Inventory on volatile organic compounds (used for the National Acid Precipitation Assessment Program); (4) Particulate Matter Species Manual (EPA); and (5) Toxics Emission Inventory (National Aeronautics and Space Administration). It also offers information on emission control technologies for municipal waste combustors.

  17. Evolution of the Air Toxics under the Big Sky Program

    Science.gov (United States)

    Marra, Nancy; Vanek, Diana; Hester, Carolyn; Holian, Andrij; Ward, Tony; Adams, Earle; Knuth, Randy

    2011-01-01

    As a yearlong exploration of air quality and its relation to respiratory health, the "Air Toxics Under the Big Sky" program offers opportunities for students to learn and apply science process skills through self-designed inquiry-based research projects conducted within their communities. The program follows a systematic scope and sequence…

  18. SNRB{trademark} air toxics monitoring. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-01

    Babcock & Wilcox (B&W) is currently conducting a project under the DOE`s Clean Coal Technology (CCT II) Program to demonstrate its SO{sub x}NO{sub x}-Rox Box{trademark} (SNRB{trademark}) process in a 5 MWe Field Demonstration Unit at Ohio Edison`s R. E. Burger Plant near Shadyside, Ohio. The objective of the SNRB{trademark} Air Toxics Monitoring Project was to provide data on SNRB{trademark} air toxics emissions control performance to B&W and to add to the DOE/EPRI/EPA data base by quantifying the flow rates of selected hazardous substances (or air toxics) in all of the major input and output streams of the SNRB{trademark} process as well as the power plant. Work under the project included the collection and analysis of representative samples of all major input and output streams of the SNRB{trademark} demonstration unit and the power plant, and the subsequent laboratory analysis of these samples to determine the partitioning of the hazardous substances between the various process streams. Material balances for selected air toxics were subsequently calculated around the SNRB{trademark} and host boiler systems, including the removal efficiencies across each of the major air pollution control devices. This report presents results of the SNRB{trademark} Air Toxics Monitoring Project. In addition to the Introduction, a brief description of the test site, including the Boiler No. 8 and the SNRB{trademark} process, is included in Section H. The concentrations of air toxic emissions are presented in Section II according to compound class. Material balances are included in Section IV for three major systems: boiler, electrostatic precipitator, and SNRB{trademark}. Emission factors and removal efficiencies are also presented according to compound class in Sections V and VI, respectively. A data evaluation is provided in Section VII.

  19. National Air Toxics Assessment - 2002, EPA Region 2 (EPA.AIR.NATA99_R2)

    Data.gov (United States)

    U.S. Environmental Protection Agency — This data layer is based on the model results of the 1999 National-Scale Assessment (N-SA), a part of the National Air Toxics Assessment (NATA), conducted by EPA's...

  20. National Air Toxics Assessment - 2005, EPA Region 2 (EPA.AIR.NATA99_R2)

    Data.gov (United States)

    U.S. Environmental Protection Agency — This data layer is based on the model results of the 1999 National-Scale Assessment (N-SA), a part of the National Air Toxics Assessment (NATA), conducted by EPA's...

  1. National Air Toxics Assessment - 1999, EPA Region 2 (EPA.AIR.NATA99_R2)

    Data.gov (United States)

    U.S. Environmental Protection Agency — This data layer is based on the model results of the 1999 National-Scale Assessment (N-SA), a part of the National Air Toxics Assessment (NATA), conducted by EPA's...

  2. Commercial Air Carrier Vulnerabilities to Information Operations

    Science.gov (United States)

    2007-11-02

    GMO /ENS/02E-11 DEPARTMENT OF THE AIR FORCE AIR UNIVERSITY AIR FORCE INSTITUTE OF TECHNOLOGY Wright-Patterson Air Force Base, Ohio...AFIT/ GMO /ENS/02E-11 COMMERCIAL AIR CARRIER VULNERABILITIES TO INFORMATION OPERATIONS...networks that without them, “there is no water coming out of your tap; there is no electricity lighting your room; there is no food being transported to

  3. Grandfather regulations, new source bias, and state air toxics regulations

    Energy Technology Data Exchange (ETDEWEB)

    Levinson, Arik [University of Wisconsin Economics Department, 1180 Observatory Drive, Madison, WI 53706 (United States)

    1999-02-01

    This paper uses plant-level data from the Census of Manufactures and the variation in toxic air pollution regulations across states to measure the effects of laws that are more stringent for new sources of pollution than for existing sources (so-called `grandfather` regulations). Of particular interest is the resulting `new source bias` and its effects on capital vintage and investment. Two industries are examined: commercial printing, which has a local product market; and paint manufacturing, which has a more national market. In general, there seem to be no statistically significant differences in capital vintage or investment between plants in states that grandfather new sources of pollution, plants in states that have no air toxics regulations, and plants in states that regulate both new and existing sources

  4. Air toxics evaluation of ABB Combustion Engineering Low-Emission Boiler Systems

    Energy Technology Data Exchange (ETDEWEB)

    Wesnor, J.D. [ABB/Combustion Engineering, Inc., Windsor, CT (United States)

    1993-10-26

    The specific goals of the program are to identify air toxic compounds that might be emmitted from the new boiler with its various Air Pollution Control device for APCD alternatives in levels of regulatory concern. For the compounds thought to be of concern, potential air toxic control methodologies will be suggested and a Test Protocol will be written to be used in the Proof of Concept and full scale tests. The following task was defined: Define Replations and Standards; Identify Air Toxic Pollutants of Interest to Interest to Utility Boilers; Assesment of Air Toxic By-Products; State of the Art Assessment of Toxic By-Product Control Technologies; and Test Protocol Definition.

  5. Air toxic emissions from snowmobiles in Yellowstone National Park.

    Science.gov (United States)

    Zhou, Yong; Shively, David; Mao, Huiting; Russo, Rachel S; Pape, Bruce; Mower, Richard N; Talbot, Robert; Sive, Barkley C

    2010-01-01

    A study on emissions associated with oversnow travel in Yellowstone National Park (YNP) was conducted for the time period of February 13-16, 2002 and February 12-16, 2003. Whole air and exhaust samples were characterized for 85 volatile organic compounds using gas chromatography. The toxics including benzene, toluene, ethylbenzene, xylenes (p-, m-, and o-xylene), and n-hexane, which are major components of two-stroke engine exhaust, show large enhancements during sampling periods resulting from increased snowmobile traffic. Evaluation of the photochemical history of air masses sampled in YNP revealed that emissions of these air toxics were (i) recent, (ii) persistent throughout the region, and (iii) consistent with the two-stroke engine exhaust sample fingerprints. The annual fluxes were estimated to be 0.35, 1.12, 0.24, 1.45, and 0.36 Gg yr(-1) for benzene, toluene, ethylbenzene, xylenes, and n-hexane, respectively, from snowmobile usage in YNP. These results are comparable to the flux estimates of 0.23, 0.77, 0.17, and 0.70 Gg yr(-1) for benzene, toluene, ethylbenzene, and xylenes, respectively, that were derived on the basis of (i) actual snowmobile counts in the Park and (ii) our ambient measurements conducted in 2003. Extrapolating these results, annual emissions from snowmobiles in the U.S. appear to be significantly higher than the values from the EPA National Emissions Inventory (1999). Snowmobile emissions represent a significant fraction ( approximately 14-21%) of air toxics with respect to EPA estimates of emissions by nonroad vehicles. Further investigation is warranted to more rigorously quantify the difference between our estimates and emission inventories.

  6. Information Search of Toxic-Free Ammunition

    Science.gov (United States)

    1994-04-01

    evolved over the years, and virtually all current primers use lead styphnate , and exhaust lead, barium , and antimony as products of combustion. These primer...Policy and Regulations 9 3.2 Procedures and Infrastructure 11 Section 4 Determining Criteria for Toxicity 14 4.1 General 14 4.2 Lead 15 4.3 Barium 15 4.4...antimony and barium are not indicated on this list, but this certainly does not mean that they are not toxic. There are a number of more complete

  7. Warning labels. A source of toxicity information for parents.

    Science.gov (United States)

    Benson, B E; Klein-Schwartz, W; Oderda, G M; Lucy, J S

    1984-08-01

    The Hazardous Substances Act specifies that warning labels for household products contain specific signal words. This study was designed to determine whether this warning label format provides enough information for parents to accurately assess product toxicity. One hundred forty-two parents from two different sites (community health clinic, private pediatrician's office) were asked to rate the toxicity of four common household products (Crystal Drano, Lysol Basin/Tub and Tile Cleaner, Clorox Bleach, Tempera Poster Paint) and four imaginary products based on the warning labels found on them. Parents had a fairly accurate perception of the toxicity of products and the toxicity to be anticipated based on the warning label. There was considerable variability in response for products which were less toxic or nontoxic. Confusion was noted regarding the meaning of the term nontoxic.

  8. Advanced combustor design concept to control NOx and air toxics

    Energy Technology Data Exchange (ETDEWEB)

    Eddings, E.G.; Pershing, D.W.; Molina, A.; Sarofim, A.F.; Spinti, J.P.; Veranth, J.

    1999-03-29

    Direct coal combustion needs to be a primary energy source for the electric utility industry and for heavy manufacturing during the next several decades because of the availability and economic advantage of coal relative to other fuels and because of the time required to produce major market penetration in the energy field. However, the major obstacle to coal utilization is a set of ever-tightening environmental regulations at both the federal and local level. It is, therefore, critical that fundamental research be conducted to support the development of low-emission, high-efficiency pulverized coal power systems. The objective of this program was to develop fundamental understanding regarding the impact of fuel and combustion changes on NOx formation, carbon burnout and air toxic emissions from pulverized coal (pc) combustion. During pc combustion, nitrogen in the coal can be oxidized to form nitrogen oxides (NO{sub x}). The 1990 Clean Air Act Amendments established much stricter NO{sub x} emissions limits for new and existing coal-fired plants, so there has been renewed interest in the processes by which NO{sub x} forms in pc flames. One of the least understood aspects of NO{sub x} formation from pc combustion is the process by which char-N (nitrogen remaining in the char after devolatilization) forms either NO{sub x} or N{sub 2}, and the development of a fundamental understanding of this process was a major focus of this research. The overall objective of this program was to improve the ability of combustion system designers and boiler manufacturers to build high efficiency, low emission pulverized coal systems by improving the design tools available to the industry. The specific program goals were to: Use laboratory experiments and modeling to develop fundamental understanding for a new submodel for char nitrogen oxidation (a critical piece usually neglected in most NOx models.); Use existing bench scale facilities to investigate alternative schemes to

  9. RAINS: Regional Air Pollution Information and Simulation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-01

    Only one computer model has ever been at the center of major international environmental negotiations. That model is RAINS. Twice it has been central to renegotiation of the Convention of Long-range Transboundary Air Pollution, the umbrella convention regarding air pollution across all Europe. It also underpins the European Union policy and directives on air pollution. Countries in Southeast Asia are turning to the model for help with their growing air pollution problems. RAINS will be used to determine emission ceilings for emissions of four key pollutants in EU countries - sulphur, ammonia, nitrogen oxides and volatile organic compounds. The same four pollutants are also the subject of a parallel negotiation in Geneva under the convention on Long-range Transboundary Air Pollution. The article and illustrations outline the model`s development and its structure in 1998, the historic role it has played in negotiations and some examples of its output. They highlight the central role of IIASA`s Transboundary Air Pollution project where a team of 12 works on the RAINS model and related issues. IIASA`s next goal is to develop a model of particulates pollution and incorporate it into RAINS. The information needed (such as particle sizes and chemical properties) and at what geographical scale must be identified to create an inventory of emissions suitable for RAINS modelling. 6 figs., 1 tab.

  10. Aerometric Information Retrieval System/AIRS Facility Subsystem (AIRS/AFS)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Aerometric Information Retrieval System/AIRS Facility Subsystem (AIRS/AFS) is a database that provides information on air releases from various stationary...

  11. Identification of Chemical Toxicity Using Ontology Information of Chemicals

    Directory of Open Access Journals (Sweden)

    Zhanpeng Jiang

    2015-01-01

    Full Text Available With the advance of the combinatorial chemistry, a large number of synthetic compounds have surged. However, we have limited knowledge about them. On the other hand, the speed of designing new drugs is very slow. One of the key causes is the unacceptable toxicities of chemicals. If one can correctly identify the toxicity of chemicals, the unsuitable chemicals can be discarded in early stage, thereby accelerating the study of new drugs and reducing the R&D costs. In this study, a new prediction method was built for identification of chemical toxicities, which was based on ontology information of chemicals. By comparing to a previous method, our method is quite effective. We hope that the proposed method may give new insights to study chemical toxicity and other attributes of chemicals.

  12. Concentrations of air toxics in motor vehicle-dominated environments.

    Science.gov (United States)

    Fujita, Eric M; Campbell, David E; Zielinska, Barbara; Arnott, William P; Chow, Judith C

    2011-02-01

    We at the Desert Research Institute (DRI*) measured volatile organic compounds (VOCs), including several mobile-source air toxics (MSATs), particulate matter with a mass mean aerodynamic diameter model calculations attributed the sum of BTEX almost exclusively to gasoline engine exhaust for on-road samples and all but 5% to 10% of the BTEX at the three near-road sites. CMB analysis attributed 46% to 52% (+/- 7) of the ambient total particulate carbon (TC) at the three near-road sites to diesel exhaust and 10% to 17% (+/- 7) to gasoline exhaust; it attributed about 90% of the ambient elemental carbon (EC) concentrations (measured as refractory carbon using the thermal evolution method) to diesel exhaust. Diesel particulate carbon (DPC) concentrations were estimated by multiplying the mean ratio of TC to EC from the source-dominated ambient samples collected on road on Terminal Island (1.30 +/- 0.28), which is located between the Long Beach and Los Angeles ports, with the measured ambient EC concentrations at the three near-road sites. DPC estimates from EC measurements correlate well with the diesel source contributions calculated with the CMB model. The indication from these apportionments that BC or EC is a good surrogate for diesel exhaust is further supported by the positive correlation of on-road BC concentrations with volumes of truck traffic. Traffic counts have been used in past health assessment studies as surrogates for estimating near-road exposure concentrations with appropriate weighting for proximity to the road. However, the results of this study show that it is necessary to account for the proportion of diesel trucks to total vehicular traffic because of the disproportionate contribution of diesel exhaust to BC and to directly emitted PM. Alternatively, easily measured pollutants such as CO and BC can serve as reasonable surrogates for MSATs (e.g., BTEX and BD) and DPC, respectively. Measuring CO and BC is a reasonably cost-effective approach to

  13. Biodiesel and Cold Temperature Effect on Speciated Mobile Source Air Toxics from Modern Diesel Trucks

    Science.gov (United States)

    Speciated volatile organic compounds (VOCs) with a particular focus on mobile source air toxics (MSATs) were measured in diesel exhaust from three heavy-duty trucks equipped with modern aftertreatment technologies. Emissions testing was conducted on a temperature controlled chass...

  14. Biodiesel and Cold Temperature Effects on Speciated Mobile Source Air Toxics from Modern Diesel Trucks

    Science.gov (United States)

    Speciated volatile organic compounds (VOCs) with a particular focus on mobile source air toxics (MSATs) were measured in diesel exhaust from three heavy-duty trucks equipped with modern aftertreatment technologies. Emissions testing was conducted on a temperature controlled chass...

  15. Air pollution information needs and the knowledge, attitudes and behaviour of Canadians : final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-01-01

    In the fall of 2001, the Environics Research Group conducted a national survey of 1,213 Canadians in order to provide Health Canada with public opinion on clean air issues. The topic areas included: concerns regarding air pollution; level of concern regarding air pollution; willingness for personal action; roles and responsibilities of government, industry and individuals; determinants of health; perceived effects of air pollution on health; personal health conditions; receipt of advice on the relationship between air pollution and health; information needs and preferred channels of information; familiarity with the air quality index; and, perceived sources of air pollution. According to survey results, Canadians think air pollution, pollution in general, and water quality are the most important environmental problems. They are most concerned about the manufacture, use and disposal of toxic chemicals, water quality and air quality, and less concerned about the depletion of the ozone layer and the use of biotechnology in agriculture and food products. Results suggest that most Canadians believe that air pollution significantly affects the health of Canadians. Approximately 25 per cent of Canadians feel they suffer from respiratory problems resulting from air pollution. In general, they think indoor and outdoor air pollution have equal effect on their health. The survey also indicated that Canadians think government regulations and enforcement are more effective in combating air pollution than voluntary action by individuals or companies. tabs., figs.

  16. Identification of Chemicals of Interest to the Department of Defense and U.S. Air Force Among the U.S. Environmental Protection Agency’s Integrated Risk Information System Chemicals that are Due for Reassessment of their Toxicity Values

    Science.gov (United States)

    2010-03-16

    10-087, 16 March 2010 LIST OF ACRONYMS ATSDR Agency for Toxic Substances and Disease Registry CASRN Chemical Abstract Services Registry Number...included 473 chemicals with Chemical Abstract Services Registry Numbers (CASRNs) that are evaluated in this report (additional detail in Appendix A). The... Chemical Abstract Services Registry Numbers (CASRNs): 2,4-/2,6- dinitrotoluene mixture; refractory ceramic fibers; uranium, soluble salts; nickel, soluble

  17. Carcinogenic Air Toxics Exposure and Their Cancer-Related Health Impacts in the United States

    Science.gov (United States)

    Zhou, Ying; Li, Chaoyang; Huijbregts, Mark A. J.; Mumtaz, M. Moiz

    2015-01-01

    Public health protection from air pollution can be achieved more effectively by shifting from a single-pollutant approach to a multi-pollutant approach. To develop such multi-pollutant approaches, identifying which air pollutants are present most frequently is essential. This study aims to determine the frequently found carcinogenic air toxics or hazardous air pollutants (HAPs) combinations across the United States as well as to analyze the health impacts of developing cancer due to exposure to these HAPs. To identify the most commonly found carcinogenic air toxics combinations, we first identified HAPs with cancer risk greater than one in a million in more than 5% of the census tracts across the United States, based on the National-Scale Air Toxics Assessment (NATA) by the U.S. EPA for year 2005. We then calculated the frequencies of their two-component (binary), and three-component (ternary) combinations. To quantify the cancer-related health impacts, we focused on the 10 most frequently found HAPs with national average cancer risk greater than one in a million. Their cancer-related health impacts were calculated by converting lifetime cancer risk reported in NATA 2005 to years of healthy life lost or Disability-Adjusted Life Years (DALYs). We found that the most frequently found air toxics with cancer risk greater than one in a million are formaldehyde, carbon tetrachloride, acetaldehyde, and benzene. The most frequently occurring binary pairs and ternary mixtures are the various combinations of these four air toxics. Analysis of urban and rural HAPs did not reveal significant differences in the top combinations of these chemicals. The cumulative annual cancer-related health impacts of inhaling the top 10 carcinogenic air toxics included was about 1,600 DALYs in the United States or 0.6 DALYs per 100,000 people. Formaldehyde and benzene together contribute nearly 60 percent of the total cancer-related health impacts. Our study shows that although there are many

  18. Current Status of Air Toxics Management and Its Strategies for Controlling Emissions in Taiwan

    Directory of Open Access Journals (Sweden)

    Wen-Tien Tsai

    2016-04-01

    Full Text Available Since the 1970s, hazardous air pollutants (HAPs, so-called air toxics, have been of great concern because they can cause serious human health effects and have adverse effects on the environment. More noticeably, some of them are known to be human carcinogens. The objective of this paper is to investigate the regulatory systems and human health effects of air toxics which have been designated by the Taiwan government under the Air Pollution Control Act. These toxic air pollutants include acutely toxic gas (i.e., ammonia, chlorine, fluorides, hydrochloric acid, hydrogen cyanide, hydrogen sulfide, nitric acid, phosphoric acid and sulfuric acid, gas containing heavy metals, and carcinogenic chemicals (including formaldehyde, vinyl chloride, asbestos and matter containing asbestos, dioxins and furans, volatile organic compounds, polycyclic aromatic hydrocarbons, and polychlorinated biphenyls. In line with international concern about the carcinogenic risk and environmental persistence of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDDs/PCDFs and heavy metals in recent years, the current status in monitoring and reducing the emissions of PCDDs/PCDFs from stationary sources was analyzed as a case study in the present study. Furthermore, the control strategies for reducing emissions of air toxics from stationary sources in Taiwan were also addressed.

  19. Advanced combustor design concepts to control NO{sub x} and air toxics. Quarterly report

    Energy Technology Data Exchange (ETDEWEB)

    Pershing, D.W.; Lighty, J.; Veranth, J. [Utah Univ., Salt Lake City, UT (United States). Coll. of Engineering; Sarofim, A.; Goel, S. [Massachusetts Inst. of Tech., Cambridge, MA (United States)

    1995-04-28

    The University of Utah, Massachusetts Institute of Technology (MIT), Reaction Engineering International (REI) and ABB/Combustion Engineering have joined together in this research proposal to develop fundamental understanding regarding the impact of fuel and combustion changes on ignition stability and flame characteristics because these critically affect: NO{sub x} emissions, carbon burnout, and emissions of air toxics; existing laboratory and bench scale facilities are being used to generate critical missing data which will be used to improve the NO{sub x} and carbon burnout submodels in comprehensive combustion simulation tools currently being used by industrial boiler manufacturers. To ensure effective and timely transfer of This technology, a major manufacturer (ABB) and a combustion model supplier (REI) have been included as part of the team from the early conception of the proposal. ABB/Combustion Engineering is providing needed fundamental data on the extent of volatile evolution from commercial coals as well as background information on current design needs in industrial practice. MIT is responsible for the development of an improved char nitrogen oxidation model which will ultimately be incorporated into an enhanced NO{sup x} submodel. Reaction Engineering International is providing the lead engineering staff for the experimental studies and an overall industrial focus for the work based on their use of the combustion simulation tools for a wide variety of industries. The University of Utah is conducting bench scale experimentation to (1) investigate alternative methods for enhancing flame stability to reduce NO{sub x} emissions and (2) characterize air toxic emissions under ultralow NO{sub x} conditions. Accomplishments for this quarter are presented to the solid sampling system and char nitrogen modeling.

  20. Toxic potency and effects of diffuse air pollution

    NARCIS (Netherlands)

    Hamers, T.H.M.

    2002-01-01

    Diffuse air pollution consists of an omnipresent complex mixture of pollutants that is emitted from many widely dispersed sources as traffic, industries, households, energy plants, waste incinerators, and agriculture. It can be deposited in relatively remote areas as a result of (long-range) airborn

  1. Air Pollution, A Scientists' Institute for Public Information Workbook.

    Science.gov (United States)

    Nadler, Allen A.; And Others

    Documentation is given on the known and potential effects of air pollution on human health, weather conditions, and biosphere. Practical applications of this information are discussed, with special reference to the Federal Air Quality Act and to the planning of urban expressways. Problems in defining standards of air quality are discussed.…

  2. Air toxic emissions from the combustion of coal: Identifying and quantifying hazardous air pollutants from US coals

    Energy Technology Data Exchange (ETDEWEB)

    Szpunar, C.B.

    1992-09-01

    This report addresses the key air toxic emissions likely to emanate from continued and expanded use of domestic coal. It identifies and quantifies those trace elements specified in the US 1990 Clean Air Act Amendments, by tabulating selected characterization data on various source coals by region, state, and rank. On the basis of measurements by various researchers, this report also identifies those organic compounds likely to be derived from the coal combustion process (although their formation is highly dependent on specific boiler configurations and operating conditions).

  3. Semiconductor Manufacturing Final Air Toxics Rules Fact Sheets

    Science.gov (United States)

    This page contains a February 2003 fact sheet for the final NESHAP for Semiconductor Manufacturing. This page also contains a July 2008 fact sheet with information regarding the final amendments to the 2003 final rule for the NESHAP.

  4. Air Force JROTC: Introduction and Information Brief

    Science.gov (United States)

    2015-04-01

    Requirements • Leaders, Teachers, Mentors, & Guides who care about making a positive impact on our cadets • Instructor Training - Junior Instructor...Curriculum In Action (Field Trips) • Kitty Hawk Air Society • Orienteering • Model Rocketry & Radio Controlled Aircraft Clubs • Incentive flights in...Support unit’s AFJROTC Booster Club • Encourage parent support & involvement • Visit & partner with other AFJROTC units, ROTC units, Air Force

  5. CORONA DESTRUCTION: AN INNOVATIVE CONTROL TECHNOLOGY FOR VOCS AND AIR TOXICS

    Science.gov (United States)

    This paper discusses the work and results to date leading to the demonstration of the corona destruction process at pilot scale. The research effort in corona destruction of volatile organic compounds (VOCs) and air toxics has shown significant promise for providing a valuable co...

  6. Excretory nitrogen metabolism and defence against ammonia toxicity in air-breathing fishes.

    Science.gov (United States)

    Chew, S F; Ip, Y K

    2014-03-01

    With the development of air-breathing capabilities, some fishes can emerge from water, make excursions onto land or even burrow into mud during droughts. Air-breathing fishes have modified gill morphology and morphometry and accessory breathing organs, which would tend to reduce branchial ammonia excretion. As ammonia is toxic, air-breathing fishes, especially amphibious ones, are equipped with various strategies to ameliorate ammonia toxicity during emersion or ammonia exposure. These strategies can be categorized into (1) enhancement of ammonia excretion and reduction of ammonia entry, (2) conversion of ammonia to a less toxic product for accumulation and subsequent excretion, (3) reduction of ammonia production and avoidance of ammonia accumulation and (4) tolerance of ammonia at cellular and tissue levels. Active ammonia excretion, operating in conjunction with lowering of ambient pH and reduction in branchial and cutaneous NH₃ permeability, is theoretically the most effective strategy to maintain low internal ammonia concentrations. NH₃ volatilization involves the alkalization of certain epithelial surfaces and requires mechanisms to prevent NH₃ back flux. Urea synthesis is an energy-intensive process and hence uncommon among air-breathing teleosts. Aestivating African lungfishes detoxify ammonia to urea and the accumulated urea is excreted following arousal. Reduction in ammonia production is achieved in some air-breathing fishes through suppression of amino acid catabolism and proteolysis, or through partial amino acid catabolism leading to alanine formation. Others can slow down ammonia accumulation through increased glutamine synthesis in the liver and muscle. Yet, some others develop high tolerance of ammonia at cellular and tissue levels, including tissues in the brain. In summary, the responses of air-breathing fishes to ameliorate ammonia toxicity are many and varied, determined by the behaviour of the species and the nature of the environment in

  7. Development of Electrostatically Enhanced Core Separater for Particulate Air Toxics Control

    Energy Technology Data Exchange (ETDEWEB)

    Eason, B.H.; Smolensky, L.A.; Wysk, S.R.; Altman, R.F.; Harrison, W.A.; Hardman, R.R.

    1997-12-31

    The Clean Air Act Amendments of 1990 have identified 189 chemical elements and compounds as hazardous air pollutants (HAPs). The U.S. Environmental Protection Agency (EPA) has been given the task of evaluating the health risks of these so-called air toxics and determining their acceptable emission rates. The U.S. Department of Energy (DOE), in cooperation with private industry, is sponsoring research into developing new air toxic emission control technologies. Coal typically contains trace amounts of HAPS, the species and amounts vary with coal type and source. Combustion of coal in Fossil Energy Power Systems releases these HAPs into the combustion gas where they flow to the stack by passing through the gas cleanup system. Except for mercury and selenium, the HAPs exist primarily in the solid phase temperatures typical of flue gases so they can be removed by particulate cleanup systems. In fact, these solid phase HAPs are removed with approximately the same efficiency as the other particulate matter. Table 1 shows the removal efficiency of 15 HAPs by an electrostatic precipitator having an efficiency of approximately 99 percent. These results suggest that very high removal efficiencies of particulate HAPs can be achieved by using a very high efficiency particulate collector. Epidemiological studies` suggest that there may be health benefits from reducing concentrations of particulate matter in the ambient air. This paper will discuss the development of a very high efficiency particulate collector called the Electrostatically Enhanced Core Separator (EECS) system that may have the potential to significantly reduce the emission rates of both particulates and particulate air toxics from Fossil Energy Power Systems.

  8. Risk of leukemia in relation to exposure to ambient air toxics in pregnancy and early childhood.

    Science.gov (United States)

    Heck, Julia E; Park, Andrew S; Qiu, Jiaheng; Cockburn, Myles; Ritz, Beate

    2014-07-01

    There are few established causes of leukemia, the most common type of cancer in children. Studies in adults suggest a role for specific environmental agents, but little is known about any effect from exposures in pregnancy to toxics in ambient air. In our case-control study, we ascertained 69 cases of acute lymphoblastic leukemia (ALL) and 46 cases of acute myeloid leukemia (AML) from California Cancer Registry records of children leukemia associated with one interquartile range increase in air toxic exposure. Risk of ALL was elevated with 3(rd) trimester exposure to polycyclic aromatic hydrocarbons (OR=1.16, 95% CI 1.04, 1.29), arsenic (OR=1.33, 95% CI 1.02, 1.73), benzene (OR=1.50, 95% CI 1.08, 2.09), and three other toxics related to fuel combustion. Risk of AML was increased with 3rd trimester exposure to chloroform (OR=1.30, 95% CI 1.00, 1.69), benzene (1.75, 95% CI 1.04, 2.93), and two other traffic-related toxics. During the child's first year, exposure to butadiene, ortho-xylene, and toluene increased risk for AML and exposure to selenium increased risk for ALL. Benzene is an established cause of leukemia in adults; this study supports that ambient exposures to this and other chemicals in pregnancy and early life may also increase leukemia risk in children.

  9. Toxics Release Inventory Chemical Hazard Information Profiles (TRI-CHIP) Dataset

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Toxics Release Inventory (TRI) Chemical Hazard Information Profiles (TRI-CHIP) dataset contains hazard information about the chemicals reported in TRI. Users can...

  10. Evaluation of a possible association of urban air toxics and asthma

    Energy Technology Data Exchange (ETDEWEB)

    Leikauf, G.D.; Kline, S.; Albert, R.E.; Baxter, C.S. [Univ. of Cincinnati Medical Center, OH (United States)] [and others

    1995-09-01

    The prevalence of asthma, measured either as the frequency of hospital admission or number of deaths attributed to asthma, has increased over the last 15 to 20 years. Rapid increases in disease prevalence are more likely to be attributable to environmental than genetic factors. inferring from past associations between air pollution and asthma, it is feasible that changes in the ambient environment could contribute to this increase in morbidity and mortality. Scientific evaluation of the links between air pollution and the exacerbation of asthma is incomplete, however. Currently, criteria pollutants [SO{sub x}NO{sub x}, O{sub 3}, CO, Pb, particulate matter (PM{sub 10})] and other risk factors (exposure to environmental tobacco smoke, volatile organic compounds, etc.) are constantly being evaluated as to their possible contributions to this situation. Data from these studies suggest that increases in respiratory disease are associated with exposures to ambient concentrations of particulate and gaseous pollutants. Similarly, exposure to environmental tobacco smoke, also a mixture of particles and gases and that current measurements of air pollution are, in part, indirect in that the concentrations of criteria pollutants are acting as surrogates of our exposure to a complex mixture. Other irritant air pollutants, including certain urban air toxics, are associated with asthma in occupational settings and may interact with criteria pollutants in ambient air to exacerbate asthma. 179 refs., 2 figs., 18 tabs.

  11. Measurement and modeling of exposure to selected air toxics for health effects studies and verification by biomarkers.

    Science.gov (United States)

    Harrison, Roy M; Delgado-Saborit, Juana Maria; Baker, Stephen J; Aquilina, Noel; Meddings, Claire; Harrad, Stuart; Matthews, Ian; Vardoulakis, Sotiris; Anderson, H Ross

    2009-06-01

    The overall aim of our investigation was to quantify the magnitude and range of individual personal exposures to a variety of air toxics and to develop models for exposure prediction on the basis of time-activity diaries. The specific research goals were (1) to use personal monitoring of non-smokers at a range of residential locations and exposures to non-traffic sources to assess daily exposures to a range of air toxics, especially volatile organic compounds (VOCs) including 1,3-butadiene and particulate polycyclic aromatic hydrocarbons (PAHs); (2) to determine microenvironmental concentrations of the same air toxics, taking account of spatial and temporal variations and hot spots; (3) to optimize a model of personal exposure using microenvironmental concentration data and time-activity diaries and to compare modeled exposures with exposures independently estimated from personal monitoring data; (4) to determine the relationships of urinary biomarkers with the environmental exposures to the corresponding air toxic. Personal exposure measurements were made using an actively pumped personal sampler enclosed in a briefcase. Five 24-hour integrated personal samples were collected from 100 volunteers with a range of exposure patterns for analysis of VOCs and 1,3-butadiene concentrations of ambient air. One 24-hour integrated PAH personal exposure sample was collected by each subject concurrently with 24 hours of the personal sampling for VOCs. During the period when personal exposures were being measured, workplace and home concentrations of the same air toxics were being measured simultaneously, as were seasonal levels in other microenvironments that the subjects visit during their daily activities, including street microenvironments, transport microenvironments, indoor environments, and other home environments. Information about subjects' lifestyles and daily activities were recorded by means of questionnaires and activity diaries. VOCs were collected in tubes packed

  12. Dimensions of Air Traffic Control Tower Information Needs: From Information Requests to Display Design

    Science.gov (United States)

    Durso, Francis T.; Johnson, Brian R.; Crutchfield, Jerry M.

    2010-01-01

    In an effort to determine the information needs of tower air traffic controllers, instructors from the Federal Aviation Administration's Academy in Oklahoma City were asked to control traffic in a high-fidelity tower cab simulator. Information requests were made apparent by eliminating access to standard tower information sources. Instead,…

  13. Bridging the air gap: an information assurance perspective

    OpenAIRE

    Richardson, Christopher

    2012-01-01

    The military has 5 domains of operations: Land, Sea, Air, Space and now Cyber. This 5th Domain is a heterogeneous network (of networks) of Communication and Information Systems (CIS) which were designed and accredited to meet Netcentric capability requirements; to be robust, secure and functional to the organisation’s needs. Those needs have changed. In the globalised economy and across the Battlespace, organisations now need to share information. Keeping our secrets, secret has been the watc...

  14. Assignment Procedures in the Air Force Procurement Management Information System.

    Science.gov (United States)

    Ward, Joe H., Jr.; And Others

    An overview is presented of the procedure for offering jobs in the Air Force Procurement Management Information System (PROMIS), an assignment system which makes possible the use of human resources research findings to improve individual personnel assignments. A general framework for viewing personnel assignment systems is presented; then job…

  15. AQUIS: An air quality and permit information management system

    Energy Technology Data Exchange (ETDEWEB)

    Smith, A.E.; Huber, C.C.; Tschanz, J. (Argonne National Lab., IL (USA)); Ryckman, S.J. Jr. (Air Force Logistics Command, Wright-Patterson AFB, OH (USA))

    1991-01-01

    The Air Quality Utility Information System (AQUIS) is a data base management system that operates on a dedicated, IBM-compatible personal computer using dBASE IV. AQUIS is in operation at six of the seven US Air Force Logistics Command (AFLC) bases to assist with the management of the source inventory, permit tracking, and the estimating and tracking of emissions. The system also provides environmental management personnel with information on regulatory requirements and other compliance information. An AFLC base can have over 500 regulated or unregulated emission sources, and the task of tracking and correlating emissions, sources, and permits is substantial. AQUIS is a comprehensive management tool that provides a single system for storing and accessing information previously available only in multiple, uncorrelated files. This paper discusses the development of the system and provides an overview of the system structure and the relationship of that structure to sources in the field. Certain features such as the linking capability and compound-specific emissions are highlighted. The experience of environmental managers, the ultimate system users, is discussed, including specific ways in which AQUIS has proven useful in responding to managers' needs for air quality information. 10 refs., 3 figs., 1 tab.

  16. Studies with the USF/NASA toxicity screening test method - Effect of air flow and effect of fabric dye

    Science.gov (United States)

    Hilado, C. J.; Lopez, M. T.

    1976-01-01

    One sample each of commercial polyurethane and polychloroprene flexible foams were evaluated using the USF/NASA toxicity screening test method. Air flow rates of 0, 0.16, 16, and 48 ml/sec were used to determine the effect of air flow on relative toxicity. Time to first sign of incapacitation and time to death were substantially reduced with both polyurethane and polychloroprene flexible foams by the introduction of 16 to 48 ml/sec air flow. The relative toxicity rankings of these materials were not altered by changes in air flow. Under these test conditions, the polyurethane foam consistently appeared more toxic than the polychloroprene foam. Samples of six different colors from the same fabric were evaluated separately, using the USF/NASA toxicity screening test method, to determine the effect of fabric dye, if any. The material was an upholstery fabric, consisting of 46 percent cotton, 33 percent wool, and 21 percent nylon. There appeared to be no significant effect of fabric dye on relative toxicity, for this material under these test conditions.

  17. Geographical information systems and air pollution simulation for Megalopolis' electric power plant in Peloponnese, Greece.

    Science.gov (United States)

    Theophanides, Mike; Anastassopoulou, Jane; Theophanides, Theophile

    2014-01-01

    The growth and sophistication of geographic information systems (GIS) have propelled us into a new era of environmental analyses. Air pollution is a growing concern in populated areas as many recent studies have associated high levels of pollution with increased illnesses and mortality. The study will focus on the toxicity levels incurred by radioactive lignite-burning Power Generation facilities located in Megalopolis, Greece. An estimate of pollution emissions followed by dispersion simulations for various atmospheric conditions will be given. The exercise will be integrated with a Geographical Information System (GIS) for defining the emission sources and visualizing the dispersion of pollutants over the geographical terrain. Data samples were collected from vegetation in the surrounding areas and analyzed for radioactivity. High energy levels (up to 4-5 times higher than recommended standards, (UNCEAR, 1982) were found in several samples containing (226)Ra, (232)Th, (234)Th, (40)K and (238)U. The study concludes that air quality and vegetation of the neighbouring areas is adversely affected by industrial waste. Greater pollution controls and air quality monitoring should be applied for the benefit and health of its citizens. Radioactivity in food and water and inhaled air become very dangerous for public health thus, the levels of radioactivity should be kept within UNCEAR 1982 limits.

  18. Silent Discharge Plasma Technology for the Treatment of Air Toxics and Other Applications

    Energy Technology Data Exchange (ETDEWEB)

    Rosocha, Louis A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Chase, Peter J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Gross, Michael P. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    1998-09-21

    Under this CRADA, the Los Alamos National Laboratory (LANL) and High Mesa Technologies, Inc. (HMT) carried out a joint project on the development of the silent discharge plasma (SDP) technology for the treatment of hazardous air pollutants and other hazardous or toxic chemicals. The project had two major components: a technology-demonstration part and a scale-up and commercialization part. In the first part, a small-scale, mobile SDP plasma processor, which was being developed under a CRADA with the Electric Power Research Institute (EPRI) was the mobile equipment was modified for higher capacity service and employed for an innovative remediation technologies demonstration on soil-vapor extraction off-gases at the McClellan Air Force Base near Sacramento, CA. The performance of the SDP system for the variety of volatile organic compounds (VOCs) encountered at the McClellan site was sufficiently promising to the project HMT and LANL worked together to formulate a scale-up strategy and commercialization/manufacturing plan, and to design a prototype scaled-up SDP unit. HMT and LANL are now in the final stages of completing a licensing agreement for the technology and HMT is in the process of raising funds to engineer and manufacture commercial prototype SDP equipment focused on stack-gas emissions control and environmental remediation. HMT, in collaboration with another Northern New Mexico business, Coyote Aerospace, has also been successful in receiving a Phase I Small Business Innovative Research (SBIR) award from the Army Research Office to develop, design, and construct a small non-thermal plasma reactor for laboratory studies ("Non-Thermal Plasma Reactor for Control of Fugitive Emissions of Toxic Gases")

  19. Future research needs associated with the assessment of potential human health risks from exposure to toxic ambient air pollutants

    DEFF Research Database (Denmark)

    Möller, Lennart; Schuetzle, Dennis; Autrup, Herman

    1994-01-01

    This paper presents key conclusions and future research needs from a Workshop on the Risk Assessment of Urban Air, Emissions, Exposure, Risk Identification, and Quantification, which was held in Stockholm during June 1992 by 41 participants from 13 countries. Research is recommended in the areas...... of identification and quantification of toxics in source emissions and ambient air, atmospheric transport and chemistry, exposure level assessment, the development of improved in vitro bioassays, biomarker development, the development of more accurate epidemiological methodologies, and risk quantification...

  20. Indoor air quality environmental information handbook: Combustion sources

    Energy Technology Data Exchange (ETDEWEB)

    1990-06-01

    This environmental information handbook was prepared to assist both the non-technical reader (i.e., homeowner) and technical persons (such as researchers, policy analysts, and builders/designers) in understanding the current state of knowledge regarding combustion sources of indoor air pollution. Quantitative and descriptive data addressing the emissions, indoor concentrations, factors influencing indoor concentrations, and health effects of combustion-generated pollutants are provided. In addition, a review of the models, controls, and standards applicable to indoor air pollution from combustion sources is presented. The emphasis is on the residential environment. The data presented here have been compiled from government and privately-funded research results, conference proceedings, technical journals, and recent publications. It is intended to provide the technical reader with a comprehensive overview and reference source on the major indoor air quality aspects relating to indoor combustion activities, including tobacco smoking. In addition, techniques for determining potential concentrations of pollutants in residential settings are presented. This is an update of a 1985 study documenting the state of knowledge of combustion-generated pollutants in the indoor environment. 191 refs., 51 figs., 71 tabs.

  1. 48 CFR 1552.235-78 - Data Security for Toxic Substances Control Act Confidential Business Information (DEC 1997).

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Data Security for Toxic... CONTRACT CLAUSES Texts of Provisions and Clauses 1552.235-78 Data Security for Toxic Substances Control Act...: Data Security for Toxic Substances Control Act Confidential Business Information (DEC 1997)...

  2. 76 FR 7841 - Agency Information Collection Activities; Proposed Collections; Toxic Chemical Release Reporting...

    Science.gov (United States)

    2011-02-11

    ... AGENCY Agency Information Collection Activities; Proposed Collections; Toxic Chemical Release Reporting... codes other than SIC codes 20 through 39): 212111, 212112, 212113 (correspond to SIC 12, Coal Mining (except 1241)); or 212221, 212222, 212231, 212234, 212299 (correspond to SIC 10, Metal Mining (except...

  3. Optical disk toxic information online system at Sumitomo Chemical Co. through telecommunication network in Japan

    Science.gov (United States)

    Kishida, Fumio; Omodaka, Hisakata; Ishihara, Koichiro; Yamada, Yoshinori; Kato, Hiromi

    Toxicity data about several hundred chemicals, handled and commercialized by Sumitomo Chemical Co., have been collected and estimated. These data are stored in an optical disk filing system "sanfile 8500D". Because the system is mounted with a keyword input panel "Word selecter", information retrieval system is simplified but precised. Online system through telecommunication network is extended between Sumitomo Chemical's works, laboratories, and others. Image informations are mailed from installed facsimili in sanfile 8500D directly.

  4. Toward Obtaining Reliable Particulate Air Quality Information from Satellites

    Science.gov (United States)

    Strawa, A. W.; Chatfield, R. B.; Legg, M.; Esswein, R.; Justice, E.

    2009-12-01

    Air quality agencies use ground sites to monitor air quality, providing accurate information at particular points. Using measurements from satellite imagery has the potential to provide air quality information in a timely manner with better spatial resolution and at a lower cost that can also useful for model validation. While previous studies show acceptable correlations between Aerosol Optical Depth (AOD) derived from MODIS and surface Particulate Matter (PM) measurements on the eastern US, the data do not correlate well in the western US (Al-Saadi et al., 2005; Engle-Cox et al., 2004) . This paper seeks to improve the AOD-PM correlations by using advanced statistical analysis techniques. Our study area is the San Joaquin Valley in California because air quality in this region has failed to meet state and federal attainment standards for PM for the past several years. A previous investigation found good correlation of the AOD values between MODIS, MISR and AERONET, but poor correlations (R2 ~ 0.02) between satellite-based AOD and surface PM2.5 measurements. PM2.5 measurements correlated somewhat better (R2 ~ 0.18) with MODIS-derived AOD using the Deep Blue surface reflectance algorithm (Hsu et al., 2006) rather than the standard MODIS algorithm. This level of correlation is not adequate for reliable air quality measurements. Pelletier et al. (2007) used generalized additive models (GAMs) and meteorological data to improve the correlation between PM and AERONET AOD in western Europe. Additive models are more flexible than linear models and the functional relationships can be plotted to give a sense of the relationship between the predictor and the response. In this paper we use GAMs to improve surface PM2.5 to MODIS-AOD correlations. For example, we achieve an R2 ~ 0.44 using a GAM that includes the Deep Blue AOD, and day of year as parameters. Including NOx observations, improves the R2 ~ 0.64. Surprisingly Ångström exponent did not prove to be a significant

  5. Mercury and Air Toxic Element Impacts of Coal Combustion By-Product Disposal and Utilizaton

    Energy Technology Data Exchange (ETDEWEB)

    David Hassett; Loreal Heebink; Debra Pflughoeft-Hassett; Tera Buckley; Erick Zacher; Mei Xin; Mae Sexauer Gustin; Rob Jung

    2007-03-31

    The University of North Dakota Energy & Environmental Research Center (EERC) conducted a multiyear study to evaluate the impact of mercury and other air toxic elements (ATEs) on the management of coal combustion by-products (CCBs). The ATEs evaluated in this project were arsenic, cadmium, chromium, lead, nickel, and selenium. The study included laboratory tasks to develop measurement techniques for mercury and ATE releases, sample characterization, and release experiments. A field task was also performed to measure mercury releases at a field site. Samples of fly ash and flue gas desulfurization (FGD) materials were collected preferentially from full-scale coal-fired power plants operating both without and with mercury control technologies in place. In some cases, samples from pilot- and bench-scale emission control tests were included in the laboratory studies. Several sets of 'paired' baseline and test fly ash and FGD materials collected during full-scale mercury emission control tests were also included in laboratory evaluations. Samples from mercury emission control tests all contained activated carbon (AC) and some also incorporated a sorbent-enhancing agent (EA). Laboratory release experiments focused on measuring releases of mercury under conditions designed to simulate CCB exposure to water, ambient-temperature air, elevated temperatures, and microbes in both wet and dry conditions. Results of laboratory evaluations indicated that: (1) Mercury and sometimes selenium are collected with AC used for mercury emission control and, therefore, present at higher concentrations than samples collected without mercury emission controls present. (2) Mercury is stable on CCBs collected from systems both without and with mercury emission controls present under most conditions tested, with the exception of vapor-phase releases of mercury exposed to elevated temperatures. (3) The presence of carbon either from added AC or from unburned coal can result in mercury

  6. Information draft on the development of air standards for methanol

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-01-01

    Methanol is a clear, colourless. very mobile liquid with a slightly alcoholic odour in pure form, but a repulsive pungent odour in crude form. Methanol is the raw material in the production of many gasoline additives, is used as a solvent or antifreeze in paint strippers, aerosol spray paints, wall paints, carburetor cleaners, and car windshield washer compounds. Methanol is one of the top pollutants by release quantities in Ontario, the highest release being generated by the pulp and paper industry. Other large emissions come from the plastics and synthetic resin industry. Total release to the air in Canada was 3,668 tonnes in 1996 and the top ten methanol emitting facilities were in Ontario. Methanol is readily absorbed through inhalation, ingestion and skin exposures. Once absorbed, it is oxidized to formaldehyde and then to formic acid. Common symptoms of exposure are visual disturbances, dizziness, nausea, vertigo, pain in the extremities, and headaches. No information was found as to the carcinogenicity of methanol to humans or animals. Current Ontario half-hour POI standard for methanol is 84,000 microgram/cubic meter and the 24-hour AAQC is 28,000 microgram/cubic meter. Both values were established more than 20 years ago. Review of relevant literature, summarized in this report, indicates that five US states have promulgated air quality guidelines or reference exposure levels for methanol, based on occupational exposure limits. The US Environmental Protection Agency is currently reviewing its reference concentration value for methanol. The World Health Organization and the Canadian federal government have not set air quality guidelines for methanol. 37 refs., 1 tab., appendix.

  7. Air and seawater pollution and air-sea gas exchange of persistent toxic substances in the Aegean Sea: spatial trends of PAHs, PCBs, OCPs and PBDEs.

    Science.gov (United States)

    Lammel, Gerhard; Audy, Ondřej; Besis, Athanasios; Efstathiou, Christos; Eleftheriadis, Kostas; Kohoutek, Jiři; Kukučka, Petr; Mulder, Marie D; Přibylová, Petra; Prokeš, Roman; Rusina, Tatsiana P; Samara, Constantini; Sofuoglu, Aysun; Sofuoglu, Sait C; Taşdemir, Yücel; Vassilatou, Vassiliki; Voutsa, Dimitra; Vrana, Branislav

    2015-08-01

    Near-ground air (26 substances) and surface seawater (55 substances) concentrations of persistent toxic substances (PTS) were determined in July 2012 in a coordinated and coherent way around the Aegean Sea based on passive air (10 sites in 5 areas) and water (4 sites in 2 areas) sampling. The direction of air-sea exchange was determined for 18 PTS. Identical samplers were deployed at all sites and were analysed at one laboratory. hexachlorobenzene (HCB), hexachlorocyclohexanes (HCHs) as well as dichlorodiphenyltrichloroethane (DDT) and its degradation products are evenly distributed in the air of the whole region. Air concentrations of p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) and o,p'-DDT and seawater concentrations of p,p'-DDE and p,p'-DDD were elevated in Thermaikos Gulf, northwestern Aegean Sea. The polychlorinated biphenyl (PCB) congener pattern in air is identical throughout the region, while polybrominated diphenylether (PBDE)patterns are obviously dissimilar between Greece and Turkey. Various pollutants, polycyclic aromatic hydrocarbons (PAHs), PCBs, DDE, and penta- and hexachlorobenzene are found close to phase equilibrium or net-volatilisational (upward flux), similarly at a remote site (on Crete) and in the more polluted Thermaikos Gulf. The results suggest that effective passive air sampling volumes may not be representative across sites when PAHs significantly partitioning to the particulate phase are included.

  8. 40 CFR 2.301 - Special rules governing certain information obtained under the Clean Air Act.

    Science.gov (United States)

    2010-07-01

    ... information obtained under the Clean Air Act. 2.301 Section 2.301 Protection of Environment ENVIRONMENTAL... governing certain information obtained under the Clean Air Act. (a) Definitions. For the purpose of this section: (1) Act means the Clean Air Act, as amended, 42 U.S.C. 7401 et seq. (2)(i) Emission data...

  9. The Air Force Air Program and Information Management System (APIMS): A flexible tool for managing your Title V Operating Permits

    Energy Technology Data Exchange (ETDEWEB)

    Weston, A.A.; Gordon, S.R.

    1999-07-01

    The Air Force Command Core System (CCS) is an integrated, activity-based risk management system designed to support the information needs of Environment, Safety, and Occupational Health (ESOH) professionals. These professionals are responsible for managing a complex and often dynamic set of requirements, and therefore, have a need for an information system that can readily be customized to meet their specific needs. This dynamic environment also drives the need for flexibility in the system. The Air Program Information Management System (APIMS) is a module within CCS designed to not only manage permit compliance and emission inventories, but also support the monitoring, recordkeeping, and reporting requirements related to air quality issues. This paper will describe the underlying foundation of CCS, the information linkages within the database, and then summarize the functionality available within the APIMS module to support the Air Quality Managers' information needs, placing emphasis on the flexibility the system provides to manage Title V Operating Permits.

  10. Final Air Toxics Standards for Clay Ceramics Manufacturing, Glass Manufacturing, and Secondary Nonferrous Metals Processing Area Sources Fact Sheet

    Science.gov (United States)

    This page contains a December 2007 fact sheet with information regarding the National Emissions Standards for Hazardous Air Pollutants (NESHAP) for Clay Ceramics Manufacturing, Glass Manufacturing, and Secondary Nonferrous Metals Processing Area Sources

  11. Air pollution: what matters most? : Physical, chemical and oxidative properties of air pollution components related to toxic effects

    NARCIS (Netherlands)

    Steenhof, M.

    2015-01-01

    Numerous studies have been published on the adverse health effects associated with both short- and long-term exposure to air pollution. Air pollution is a heterogeneous, complex mixture of gases, liquids, and particulate matter (PM). Up to now, PM mass concentration has been the metric of choice to

  12. Sampling of power plant stacks for air toxic emissions: Topical report for Phases 1 and 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-02-21

    Under contract with the US Department of Energy (DE-AC22-92PCO0367), Pittsburgh Energy Technology Center, Radian Corporation has conducted a test program to collect and analyze size-fractionated stack gas particulate samples for selected inorganic hazardous air pollutants (HAPS). Specific goals of the program are (1) the collection of one-gram quantities of size-fractionated stack gas particulate matter for bulk (total) and surface chemical charactization, and (2) the determination of the relationship between particle size, bulk and surface (leachable) composition, and unit load. The information obtained from this program identifies the effects of unit load, particle size, and wet FGD system operation on the relative toxicological effects of exposure to particulate emissions.

  13. Thermal Stress and Toxicity

    Science.gov (United States)

    Elevating ambient temperature above thermoneutrality exacerbates toxicity of most air pollutants, insecticides, and other toxic chemicals. On the other hand, safety and toxicity testing of toxicants and drugs is usually performed in mice and rats maintained at subthermoneutral te...

  14. The effects of closure and workload privatization on health risks estimated for air toxic emissions from McClellan AFB

    Energy Technology Data Exchange (ETDEWEB)

    Vanderbilt, P.; Castleberry, J. [CH2M Hill, Sacramento, CA (United States); Carroz, J. [SM-ALC/EMPW, McClellan AFB, CA (United States)

    1997-12-31

    In July 1995, McClellan AFB, one of five Air Force Logistics Centers, was included on the Base Realignment and Closure Commission list approved by President Clinton. The base will close by August 2001. Significant manufacturing and repair facilities are scheduled for privatization and/or reuse. The State of California requires major industrial facilities to inventory their air toxic emissions and estimate health risks using California-approved methods. This paper explores and discusses the changes in estimated health risks if McClellan AFB was split up into several parts, reducing or eliminating buffer zones, and moving fence lines closer to major air toxic emissions sources. The health risks for the entire base estimated in prior study are compared to the individual risks associated with separate operation of emission sources in various buildings on the base. For several of the buildings and operations studied, predicted health risks at the sites of maximum exposure are greater than limits proposed by the local air district as acceptable levels. Mitigation measures may be required, such as public notification, risk reduction audits, and implementation and tracking of risk reduction measures. For other buildings and operations, results demonstrate that separate ownership would result in predicted health risks within acceptable levels.

  15. In vitro toxicity testing of cigarette smoke based on the air-liquid interface exposure: A review.

    Science.gov (United States)

    Li, Xiang

    2016-10-01

    Cigarette smoke is a complex aerosol comprising particulate phase and gaseous vapour phase. The air-liquid interface exposure provides a possible technical means to implement whole smoke exposure for the assessment of tobacco products. In this review, the research progress in the in vitro toxicity testing of cigarette smoke based on the air-liquid interface exposure is summarized. The contents presented involve mainly cytotoxicity, genotoxicity, oxidative stress, inflammation, systems toxicology, 3D culture and cigarette smoke dosimetry related to cigarette smoke, as well as the assessment of electronic cigarette aerosol. Prospect of the application of the air-liquid interface exposure method in assessing the biological effects of tobacco smoke is discussed.

  16. Sampling of power plant stacks for air toxic emissions: Final report for Phases 1 and 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-28

    A test program to collect and analyze size-fractionated stack gas particulate samples for selected inorganic hazardous air pollutants (HAPs) was conducted . Specific goals of the program are (1) the collection of one-gram quantities of size-fractionated stack gas particulate matter for bulk (total) and surface chemical characterization, and (2) the determination of the relationship between particle size, bulk and surface (leachable) composition, and unit load. The information obtained from this program identifies the effects of unit load, particle size, and wet FGD system operation on the relative toxicological effects of exposure to particulate emissions. Field testing was conducted in two phases. The Phase I field program was performed over the period of August 24 through September 20, 1992, at the Tennessee Valley Authority Widows Creek Unit 8 Power Station, located near Stevenson (Jackson County), Alabama, on the Tennessee River. Sampling activities for Phase II were conducted from September 11 through October 14, 1993. Widows Creek Unit 8 is a 575-megawatt plant that uses bituminous coal averaging 3.7% sulfur and 13% ash. Downstream of the boiler, a venture wet scrubbing system is used for control of both sulfur dioxide and particulate emissions. There is no electrostatic precipitator (ESP) in this system. This system is atypical and represents only about 5% of the US utility industry. However, this site was chosen for this study because of the lack of information available for this particulate emission control system.

  17. Identifying inequitable exposure to toxic air pollution in racialized and low-income neighbourhoods to support pollution prevention

    Directory of Open Access Journals (Sweden)

    Suzanne Kershaw

    2013-05-01

    Full Text Available Numerous environmental justice studies have confirmed a relationship between population characteristics such as low-income or minority status and the location of environmental health hazards. However, studies of the health risks from exposure to harmful substances often do not consider their toxicological characteristics. We used two different methods, the unit-hazard and the distance-based approach, to evaluate demographic and socio-economic characteristics of the population residing near industrial facilities in the City of Toronto, Canada. In addition to the mass of air emissions obtained from the national pollutant release inventory (NPRI, we also considered their toxicity using toxic equivalency potential (TEP scores. Results from the unit-hazard approach indicate no significant difference in the proportion of low-income individuals living in host versus non-host census tracts (t(107 = 0.3, P = 0.735. However, using the distance-based approach, the proportion of low-income individuals was significantly higher (+5.1%, t(522 = 6.0, P <0.001 in host tracts, while the indicator for “racialized” communities (“visible minority” was 16.1% greater (t(521 = 7.2, P <0.001 within 2 km of a NPRI facility. When the most toxic facilities by non-carcinogenic TEP score were selected, the rate of visible minorities living near the most toxic NPRI facilities was significantly higher (+12.9%, t(352 = 3.5, P = 0.001 than near all other NPRI facilities. TEP scores were also used to identify areas in Toronto that face a double burden of poverty and air toxics exposure in order to prioritise pollution prevention.

  18. 76 FR 60020 - Agency Information Collection Activities: Proposed Collection; Comment Request; Ambient Air...

    Science.gov (United States)

    2011-09-28

    ... AGENCY Agency Information Collection Activities: Proposed Collection; Comment Request; Ambient Air... pollution control agencies, and tribal entities which collect and report ambient air quality data for the criteria pollutants to the EPA as well as other supporting measurements. Title: Ambient Air...

  19. Identifying inequitable exposure to toxic air pollution in racialized and low-income neighbourhoods to support pollution prevention.

    Science.gov (United States)

    Kershaw, Suzanne; Gower, Stephanie; Rinner, Claus; Campbell, Monica

    2013-05-01

    Numerous environmental justice studies have confirmed a relationship between population characteristics such as low-income or minority status and the location of environmental health hazards. However, studies of the health risks from exposure to harmful substances often do not consider their toxicological characteristics. We used two different methods, the unit-hazard and the distance-based approach, to evaluate demographic and socio-economic characteristics of the population residing near industrial facilities in the City of Toronto, Canada. In addition to the mass of air emissions obtained from the national pollutant release inventory (NPRI), we also considered their toxicity using toxic equivalency potential (TEP) scores. Results from the unit-hazard approach indicate no significant difference in the proportion of low-income individuals living in host versus non-host census tracts (t(107) = 0.3, P = 0.735). However, using the distance-based approach, the proportion of low-income individuals was significantly higher (+5.1%, t(522) = 6.0, P air toxics exposure in order to prioritise pollution prevention.

  20. The impact of information on perceived air quality

    DEFF Research Database (Denmark)

    Wilkins, K.; Wolkoff, Peder; Knudsen, Henrik Nellemose

    2007-01-01

    As indoor air quality complaints cannot be explained satisfactorily and building materials can be a major source of indoor air pollution, we hypothesized that emissions from building materials perceived as unfamiliar or annoying odors may contribute to such complaints. To test this hypothesis...

  1. Occurrence and Concentrations of Toxic VOCs in the Ambient Air of Gumi, an Electronics-Industrial City in Korea

    Directory of Open Access Journals (Sweden)

    Sung-Ok Baek

    2015-08-01

    Full Text Available This study was carried out to characterize the occurrence and concentrations of a variety of volatile organic compounds (VOCs including aliphatic, aromatic, halogenated, nitrogenous, and carbonyl compounds, in the ambient air of Gumi City, where a large number of electronics industries are found. Two field monitoring campaigns were conducted for a one year period in 2003/2004 and 2010/2011 at several sampling sites in the city, representing industrial, residential and commercial areas. More than 80 individual compounds were determined in this study, and important compounds were then identified according to their abundance, ubiquity and toxicity. The monitoring data revealed toluene, trichloroethylene and acetaldehyde to be the most significant air toxics in the city, and their major sources were mainly industrial activities. On the other hand, there was no clear evidence of an industrial impact on the concentrations of benzene and formaldehyde in the ambient air of the city. Overall, seasonal variations were not as distinct as locational variations in the VOCs concentrations, whereas the within-day variations showed a typical pattern of urban air pollution, i.e., increase in the morning, decrease in the afternoon, and an increase again in the evening. Considerable decreases in the concentrations of VOCs from 2003 to 2011 were observed. The reductions in the ambient concentrations were confirmed further by the Korean PRTR data in industrial emissions within the city. Significant decreases in the concentrations of benzene and acetaldehyde were also noted, whereas formaldehyde appeared to be almost constant between the both campaigns. The decreased trends in the ambient levels were attributed not only to the stricter regulations for VOCs in Korea, but also to the voluntary agreement of major companies to reduce the use of organic solvents. In addition, a site planning project for an eco-friendly industrial complex is believed to play a contributory

  2. "Air Toxics under the Big Sky": Examining the Effectiveness of Authentic Scientific Research on High School Students' Science Skills and Interest

    Science.gov (United States)

    Ward, Tony J.; Delaloye, Naomi; Adams, Earle Raymond; Ware, Desirae; Vanek, Diana; Knuth, Randy; Hester, Carolyn Laurie; Marra, Nancy Noel; Holian, Andrij

    2016-01-01

    "Air Toxics Under the Big Sky" is an environmental science outreach/education program that incorporates the Next Generation Science Standards (NGSS) 8 Practices with the goal of promoting knowledge and understanding of authentic scientific research in high school classrooms through air quality research. This research explored: (1)…

  3. OpenAIRE Guidelines for CRIS Managers: Supporting Interoperability of Open Research Information through Established Standards

    DEFF Research Database (Denmark)

    Houssos, Nikos; Jörg, Brigitte; Dvořák, Jan;

    2014-01-01

    their information in a way that is compatible with OpenAIRE. This contribution focuses on a specific type of data source, CRIS systems, and the respective OpenAIRE guidelines, based on CERIF XML. A range of issues, spanning different aspects of information representation and exchange, needed to be addressed...... by the guidelines in order to define a complete solution for interoperability....

  4. 48 CFR 1552.235-75 - Access to Toxic Substances Control Act Confidential Business Information (APR 1996).

    Science.gov (United States)

    2010-10-01

    ... Control Act Confidential Business Information (APR 1996). 1552.235-75 Section 1552.235-75 Federal...: Access to Toxic Substances Control Act Confidential Business Information (APR 1996) In order to perform... Control Act (TSCA) confidential business information (CBI). The Contractor and all of its...

  5. Development and deployment of AQUIS: A PC-based emission inventory calculator and air information management system

    Energy Technology Data Exchange (ETDEWEB)

    Smith, A.E.; Tschanz, J.; Monarch, M.; Narducci, P.; Bormet, S.

    1995-06-01

    The Air Quality Utility Information System (AQUIS) is a database management system. AQUIS assists users in calculation emissions, both traditional and toxic, and tracking and reporting emissions and source information. With some facilities having over 1200 sources and AQUIS calculating as many as 125 pollutants for a single source, tracking and correlating this information involve considerable effort. Originally designed for use at seven facilities of the Air Force Material Command, the user community has expanded to over 50 facilities since last reported at the 1993 Air and Waste Management Association (AWMA) annual meeting. This expansion in the user community has provided an opportunity to test the system under expanded operating conditions and in applications not anticipated during original system design. User feedback is used to determine needed enhancements and features and to prioritize the content of new releases. In responding to evolving user needs and new emission calculation procedures, it has been necessary to reconfigure AQUIS several times. Reconfigurations have ranged from simple to complex. These changes have necessitated augmenting quality assurance (QA) and validation procedures.

  6. A system for the determination of trace-level polar and non-polar toxic organic compounds in ambient air

    Energy Technology Data Exchange (ETDEWEB)

    Tipler, A.; Dang, R.; Hoberecht, H. [Perkin Elmer Corp., Norwalk, CT (United States). Fresh Aire Lab.

    1994-12-31

    A gas chromatographic system is described for the determination of toxic organic compounds in ambient air. These compounds include all those specified within the US EPA Compendium Method TO14 and some polar additional analytes under consideration for the proposed TO15 Method. The system supports both on-line and off-line (passivated canisters and adsorption tubes) methods for sampling air--providing a fully automated analysis. A key feature of the system is that liquid cryogen is not required for either the analyte preconcentration or the subsequent chromatographic separation. Water management is achieved by dry-purging an adsorbent trap upon which the sample analytes have been retained. The performance of the system is demonstrated with conventional detection systems (electron capture and flame ionization) and with a mass spectrometer.

  7. Air toxics and epigenetic effects: ozone altered microRNAs in the sputum of human subjects

    Science.gov (United States)

    Ozone (03) is a criteria air pollutant that is associated with numerous adverse health effects, including altered respiratory immune responses. Despite its deleterious health effects, possible epigenetic mechanisms underlying 03-induced health effects remain understudied. MicroRN...

  8. The Apheis project: Air Pollution and Health—A European Information System

    OpenAIRE

    Medina, Sylvia; Le Tertre, Alain; Saklad, Michael; ,

    2009-01-01

    At a time when the Health Effects Institute, Centers for Disease Control, and Environmental Protection Agency are creating an Environmental Public Health Tracking Program on Air Pollution Effects in the USA, it seemed useful to share the experience acquired since 1999 by the Apheis project (Air Pollution and Health—A European Information System), which has tracked the effects of air pollution on health in 26 European cities and continues to do so as the new Aphekom project. In particular, thi...

  9. Clinical characteristics of mephedrone toxicity reported to the UK National Poisons Information Service

    Science.gov (United States)

    James, D; Adams, R D; Spears, R; Cooper, G; Lupton, D J; Thompson, J P

    2010-01-01

    Objective To describe the patterns and clinical features of toxicity related to recreational use of mephedrone and other cathinones in the UK using data collected by the National Poisons Information Service (NPIS). Methods The number of accesses to TOXBASE, the NPIS online poisons information database, details of consecutive cases uploaded onto TOXBASE and the number and details of telephone enquiries made to the NPIS by health professionals in the UK were collected for the period March 2009 to February 2010. Results Over the year of study there were 2901 TOXBASE accesses and 188 telephone enquiries relating to cathinones, the majority relating to mephedrone (TOXBASE 1664, telephone 157), with a month-on-month increase in numbers. In 131 telephone enquiries concerning mephedrone, alone or in combination with alcohol, common clinical features reported included agitation or aggression (n=32, 24%, 95% CI 18% to 33%), tachycardia (n=29, 22%, 95% CI 16% to 30%), confusion or psychosis (n=18, 14%, 95% CI 9% to 21%), chest pain (n=17, 13%, 95% CI 8% to 20%), nausea (n=15, 11%, 95% CI 7% to 18%), palpitations (n=14, 11%, 95% CI 6% to 18%), peripheral vasoconstriction (n=10, 8%, 95% CI 4% to 14%) and headache (n=7, 5%, 95% CI 2% to 11%). Convulsions were reported in four cases (3%, 95% CI 1% to 8%). One exposed person died following cardiac arrest (1%, 95% CI 0% to 4%), although subsequent investigation suggested that mephedrone was not responsible. Conclusions Toxicity associated with recreational mephedrone use is increasingly common in the UK. Sympathomimetic adverse effects are common and severe effects are also reported. Structured data collected by the NPIS may be of use in identifying trends in poisoning and in establishing toxidromes for new drugs of abuse. PMID:20798084

  10. Analysis of air-toxics emissions, exposures, cancer risks and controllability in five urban areas. Volume 2. Controllability analysis and results

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, J.; Coleman, B.; Laich, E.; Powell, R.

    1990-04-01

    The report (Volume 2) is the second phase of a study to define the urban air toxics problem and to discern what combination of control measures can best be employed to mitigate the problem. Volume 1 of the study documented the base year analysis (nominally the year 1980), involving dispersion modeling of emissions data for 25 carcinogenic air toxics in five U.S. urban areas and a subsequent assessment of estimated aggregate cancer incidence. The Volume 2 report applies various control strategies and analyzes the resulting reduction in aggregate cancer incidence that would occur between 1980 and 1995. Control scenarios consisted of (1) efforts that were currently underway to reduce air toxics emissions at the time of the study, (2) efforts that were expected to occur by 1995, mainly national standards that were under development, and (3) a series of selected more rigorous controls.

  11. 19 CFR 122.48a - Electronic information for air cargo required in advance of arrival.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Electronic information for air cargo required in... OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY AIR COMMERCE REGULATIONS Aircraft Entry and Entry Documents; Electronic Manifest Requirements for Passengers, Crew Members, and Non-Crew Members...

  12. Enhanced, multi criteria based site selection to measure mobile source toxic air pollutants

    Science.gov (United States)

    Research studies being conducted by the U.S. Environmental Protection Agency in collaboration with the U.S. Federal Highway Administration are designed to establish relationships between concentrations of highway vehicle air pollutants and variations in these concentrations as a ...

  13. CHARACTERIZATION OF AIR TOXICS FROM AN OIL-FIRED FIRETUBE BOILER

    Science.gov (United States)

    Tests were conducted on a commercially available firetube package boiler running on #2 through #6 oils to determine the emissions levels of hazardous air pollutants (HAPs) from the combustion of four fuel oils. Flue gas was sampled to determine levels of volatile and semivolatile...

  14. Heme oxygenase-1 protects endothelial cells from the toxicity of air pollutant chemicals.

    Science.gov (United States)

    Lawal, Akeem O; Zhang, Min; Dittmar, Michael; Lulla, Aaron; Araujo, Jesus A

    2015-05-01

    Diesel exhaust particles (DEPs) are a major component of diesel emissions, responsible for a large portion of their toxicity. In this study, we examined the toxic effects of DEPs on endothelial cells and the role of DEP-induced heme oxygenase-1 (HO-1) expression. Human microvascular endothelial cells (HMECs) were treated with an organic extract of DEPs from an automobile engine (A-DEP) or a forklift engine (F-DEP) for 1 and 4h. ROS generation, cell viability, lactate dehydrogenase leakage, expression of HO-1, inflammatory genes, cell adhesion molecules and unfolded protein respone (UPR) gene were assessed. HO-1 expression and/or activity were inhibited by siRNA or tin protoporphyrin (Sn PPIX) and enhanced by an expression plasmid or cobalt protoporphyrin (CoPPIX). Exposure to 25μg/ml of A-DEP and F-DEP significantly induced ROS production, cellular toxicity and greater levels of inflammatory and cellular adhesion molecules but to a different degree. Inhibition of HO-1 enzymatic activity with SnPPIX and silencing of the HO-1 gene by siRNA enhanced DEP-induced ROS production, further decreased cell viability and increased expression of inflammatory and cell adhesion molecules. On the other hand, overexpression of the HO-1 gene by a pcDNA 3.1D/V5-HO-1 plasmid significantly mitigated ROS production, increased cell survival and decreased the expression of inflammatory genes. HO-1 expression protected HMECs from DEP-induced prooxidative and proinflammatory effects. Modulation of HO-1 expression could potentially serve as a therapeutic target in an attempt to inhibit the cardiovascular effects of ambient PM.

  15. Wet air oxidation pretreatment of biomethanated distillery effluent: mapping pretreatment efficiency in terms color, toxicity reduction and biogas generation.

    Science.gov (United States)

    Sarat Chandra, T; Malik, S N; Suvidha, G; Padmere, M L; Shanmugam, P; Mudliar, S N

    2014-04-01

    The effluents from molasses-based distilleries after biomethanation are beset with problems of intensified dark brown color, high residual COD, low biodegradability index (BOD/COD ratio Wet air oxidation (WAO) pretreatment of biomethanated distillery effluent resulted in substantial enhancement in the biodegradability index (BI) (up to 0.8). WAO pretreated effluent on anaerobic digestion indicated favorable biogas generation with methane content up to 64% along with concomitant COD reduction up to 54.75%. The HPLC analysis indicated that the pretreatment facilitated degradation of major color containing compounds-namely melanoidins, up to 97.8%. The pretreated effluent with enhanced biodegradability along with substantially reduced color also indicated positive effect on seed germination (up to 100%), implying toxicity reduction of the effluent post WAO pretreatment.

  16. Information draft on the development of air standards for acrylonitrile

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-01-01

    Acrylonitrile is a colourless liquid with a faintly sweet and pungent odour. It is widely used as a chemical intermediate in a variety of industrial and commercial products such as acrylic and modacrylic fibres, plastics, styrene-acrylonitrile, nitrile rubber resins, and acrylamide. Although not currently produced in Canada, acrylonitrile is used in the manufacture of industrial and commercial products. Acrylonitrile levels around end-use plants have been found to be significantly higher than at producing facilities. Almost all releases of acrylonitrile are to the atmosphere and one facility is responsible for all releases in Ontario. Human exposure is through air, water and food. Acrylonitrile is absorbed by inhalation, through the mouth and to some extent through the skin. Exposure at concentrations of 7 to 45 microgram/cubic meter for 20 to 45 minutes leads to irritation of the mucous membranes, nausea, headaches, and irritability. Low-grade anaemia, leukocytosis, kidney irritation and mild jaundice have also been observed. Children are more sensitive than adults. Acrylonitrile is classified as probable human carcinogen by the US Environmental Protection Agency. The current ambient air quality criterion (AAQC) in Ontario is 100 microgram/cubic metre and the half-hour interim point of impingement (POI) standard is 300 microgram/cubic meter. Review of world-wide literature showed the existence of standards in several American states. Cancer unit risks estimates have been made by the US Environmental Protection Agency as well as by the World Health Organization. 63 refs., 1 tab., appendix.

  17. Measurement and improvement of indoor air quality in an information technology classroom

    Directory of Open Access Journals (Sweden)

    Tomić Mladen A.

    2014-01-01

    Full Text Available With the rapid development of information technology equipment and its use in the teaching and learning activities, the working environment (especially indoor air quality in which students and pupils spend a great deal of time in educational institutions has been changing. Therefore, special attention must be paid to indoor air quality and comfort. It is of great importance to maintain indoor air quality in an object, such as information technology classrooms, where a large number of students spend long periods of time. Poor indoor environment can negatively affect scholarly performances and cause discomfort and poor work performance. The problem of indoor air quality in educational institutions can be more serious than in other types of objects, because of the higher concentration of students and information technology equipment. This paper analyzes the changes in air quality in an information technology classrooms, when occupied with students, for the period from March to April. The changes of indoor air temperature, relative humidity, and carbon dioxide concentration are monitored in the classroom, as well as outdoor temperature and relative humidity. Several cases are studied: the classroom with closed windows and doors (closed classroom, the classroom with natural ventilation, the classroom cooled with a split system (cooled classroom. Responses of students are followed for each case. The analysis is performed based on the measurement results and numerical simulations using the computational fluid dynamics package, and measures are proposed to improve the indoor air quality in the considered classroom.

  18. Heme oxygenase-1 protects endothelial cells from the toxicity of air pollutant chemicals

    Energy Technology Data Exchange (ETDEWEB)

    Lawal, Akeem O.; Zhang, Min; Dittmar, Michael [Division of Cardiology, David Geffen School of Medicine, University of California, Los Angeles, 10833 Le Conte Avenue, CHS 43-264, Los Angeles, CA 90095 (United States); Lulla, Aaron [Division of Cardiology, David Geffen School of Medicine, University of California, Los Angeles, 10833 Le Conte Avenue, CHS 43-264, Los Angeles, CA 90095 (United States); Molecular Toxicology Interdepartmental Program, University of California, Los Angeles (United States); Araujo, Jesus A., E-mail: JAraujo@mednet.ucla.edu [Division of Cardiology, David Geffen School of Medicine, University of California, Los Angeles, 10833 Le Conte Avenue, CHS 43-264, Los Angeles, CA 90095 (United States); Molecular Toxicology Interdepartmental Program, University of California, Los Angeles (United States); Molecular Biology Institute, University of California, Los Angeles (United States)

    2015-05-01

    Diesel exhaust particles (DEPs) are a major component of diesel emissions, responsible for a large portion of their toxicity. In this study, we examined the toxic effects of DEPs on endothelial cells and the role of DEP-induced heme oxygenase-1 (HO-1) expression. Human microvascular endothelial cells (HMECs) were treated with an organic extract of DEPs from an automobile engine (A-DEP) or a forklift engine (F-DEP) for 1 and 4 h. ROS generation, cell viability, lactate dehydrogenase leakage, expression of HO-1, inflammatory genes, cell adhesion molecules and unfolded protein respone (UPR) gene were assessed. HO-1 expression and/or activity were inhibited by siRNA or tin protoporphyrin (Sn PPIX) and enhanced by an expression plasmid or cobalt protoporphyrin (CoPPIX). Exposure to 25 μg/ml of A-DEP and F-DEP significantly induced ROS production, cellular toxicity and greater levels of inflammatory and cellular adhesion molecules but to a different degree. Inhibition of HO-1 enzymatic activity with SnPPIX and silencing of the HO-1 gene by siRNA enhanced DEP-induced ROS production, further decreased cell viability and increased expression of inflammatory and cell adhesion molecules. On the other hand, overexpression of the HO-1 gene by a pcDNA 3.1D/V5-HO-1 plasmid significantly mitigated ROS production, increased cell survival and decreased the expression of inflammatory genes. HO-1 expression protected HMECs from DEP-induced prooxidative and proinflammatory effects. Modulation of HO-1 expression could potentially serve as a therapeutic target in an attempt to inhibit the cardiovascular effects of ambient PM. - Highlights: • We examined the role of HO-1 expression on diesel exhaust particle (DEP) in endothelial cells. • DEPs exert cytotoxic and inflammatory effects on human microvascular endothelial cells (HMECs). • DEPs induce HO-1 expression in HMECs. • HO-1 protects against the oxidative stress induced by DEps. • HO-1 attenuates the proinflammatory effects

  19. Obtaining Traffic Information by Urban Air Quality Inspection

    CERN Document Server

    Ferrante, P; Nicolosi, S; Scaccianoce, G; Traverso, M; Rizzo, G

    2011-01-01

    The level of air quality in urban centres is affected by emission of several pollutants, mainly coming from the vehicles flowing in their road networks. This is a well known phenomenon that influences the quality of life of people. Despite the deep concern of researchers and technicians, we are far from a total understanding of this phenomenon. On the contrary, the availability of reliable forecasting models would constitute an important tool for administrators in order of assessing suitable actions concerning the transportation policies, public as well private. Referring to the situation of the running fleet and the measured pollutant concentrations concerning the Italian town of Palermo, a data-deduced traffic model is here derived, its truthfulness being justified by a fuzzyfication of the phenomenon. A first validation of the model is supplied by utilising the emissions characteristics and the pollutant concentrations referring to a two years period of time. This work could represent a first attempt in de...

  20. Intermedia transfer factors for fifteen toxic pollutants released to air basins in California

    Energy Technology Data Exchange (ETDEWEB)

    McKone, T.E.; Daniels, J.I. [Lawrence Livermore National Lab., CA (United States); Chiao, F.F.; Hsieh, D.P.H. [Univ. of California, Davis, CA (United States)

    1993-10-01

    This report provides a summary definition of the intermedia-transfer factors (ITFs). Methods are discussed for estimating these parameters in the absence of measured values, and the estimation errors inherent in these estimation methods are considered. A detailed summary is provided of measured and estimated ITF values for fifteen air contaminants. They include: 1,3 butadiene; cadmium; cellosolve; cellosolve acetate; chloroform; di-2-ethylhexylphthalate; 1,4-dioxame; hexachlorobenzene; inorganic arsenic; inorganic lead; nickel; tetrachloroethylene; toluene; toluene-2,4-diisocyanate; and 1,3-xylene. Recommendations are made regarding the expected value and variance in these values for use in exposure models.

  1. Using silver nano particles for sampling of toxic mercury vapors from industrial air sample

    Directory of Open Access Journals (Sweden)

    M. Osanloo

    2014-05-01

    .Conclusion: The presented adsorbent is very useful for sampling of the trace amounts of mercury vapors from air. Moreover, it can be regenerated easily is suitable or sampling at 25 to 70 °C. Due to oxidation of silver and reduction in uptake of nanoparticles, oven temperature of 245 °C is used for the recovery of metallic silver. Low amount of adsorbent, high absorbency, high repeatability for sampling, low cost and high accuracy are of the advantages of the presented method.

  2. Real-Time Cell-Electronic Sensing of Coal Fly Ash Particulate Matter for Toxicity-Based Air Quality Monitoring.

    Science.gov (United States)

    Moe, Birget; Yuan, Chungang; Li, Jinhua; Du, Haiying; Gabos, Stephan; Le, X Chris; Li, Xing-Fang

    2016-06-20

    The development of a unique bioassay for cytotoxicity analysis of coal fly ash (CFA) particulate matter (PM) and its potential application for air quality monitoring is described. Using human cell lines, A549 and SK-MES-1, as live probes on microelectrode-embedded 96-well sensors, impedance changes over time are measured as cells are treated with varying concentrations (1 μg/mL-20 mg/mL) of CFA samples. A dose-dependent impedance change is determined for each CFA sample, from which an IC50 histogram is obtained. The assay was successfully applied to examine CFA samples collected from three coal-fired power plants (CFPs) in China. The samples were separated into three size fractions: PM2.5 (10 μm). Dynamic cell-response profiles and temporal IC50 histograms of all samples show that CFA cytotoxicity depends on concentration, exposure time (0-60 h), and cell-type (SK-MES-1 > A549). The IC50 values differentiate the cytotoxicity of CFA samples based on size fraction (PM2.5 ≈ PM10-2.5 ≫ PM10) and the sampling location (CFP2 > CFP1 ≈ CFP3). Differential cytotoxicity measurements of particulates in human cell lines using cell-electronic sensing provide a useful tool for toxicity-based air quality monitoring and risk assessment.

  3. Real time measurement of transient event emissions of air toxics by tomographic remote sensing in tandem with mobile monitoring

    Science.gov (United States)

    Olaguer, Eduardo P.; Stutz, Jochen; Erickson, Matthew H.; Hurlock, Stephen C.; Cheung, Ross; Tsai, Catalina; Colosimo, Santo F.; Festa, James; Wijesinghe, Asanga; Neish, Bradley S.

    2017-02-01

    During the Benzene and other Toxics Exposure (BEE-TEX) study, a remote sensing network based on long path Differential Optical Absorption Spectroscopy (DOAS) was set up in the Manchester neighborhood beside the Ship Channel of Houston, Texas in order to perform Computer Aided Tomography (CAT) scans of hazardous air pollutants. On 18-19 February 2015, the CAT scan network detected large nocturnal plumes of toluene and xylenes most likely associated with railcar loading and unloading operations at Ship Channel petrochemical facilities. The presence of such plumes during railcar operations was confirmed by a mobile laboratory equipped with a Proton Transfer Reaction-Mass Spectrometer (PTR-MS), which measured transient peaks of toluene and C2-benzenes of 50 ppb and 57 ppb respectively around 4 a.m. LST on 19 February 2015. Plume reconstruction and source attribution were performed using the 4D variational data assimilation technique and a 3D micro-scale forward and adjoint air quality model based on both tomographic and PTR-MS data. Inverse model estimates of fugitive emissions associated with railcar transfer emissions ranged from 2.0 to 8.2 kg/hr for toluene and from 2.2 to 3.5 kg/hr for xylenes in the early morning of 19 February 2015.

  4. REAL-TIME EMISSION CHARACTERIZATION OF ORGANIC AIR TOXIC POLLUTANTS DURING STEADY STATE AND TRANSIENT OPERATION OF A MEDIUM DUTY DIESEL ENGINE

    Science.gov (United States)

    An on-line monitoring method, jet resonance-enhanced multi-photon ionization (REMPI) with time-of-flight mass spectrometry (TOFMS) was used to measure emissions of organic air toxics from a medium-duty (60 kW)diesel generator during transient and steady state operations. Emission...

  5. Identification of Information-Seeking Behaviors from Air Traffic Controllers′Eye Movements

    Institute of Scientific and Technical Information of China (English)

    Wang Yanjun; LiuYinxin; Cong Wei; Xu Xinhua; HuMinghua

    2016-01-01

    Air traffic controllers are the important parts of air traffic management system who are responsible for the safety and efficiency of the system.They make traffic management decisions based on information acquired from various sources.The understanding of their information seeking behaviors is still limited.We aim to identify controllers′behavior through the examination of the correlations between controllers′eye movements and air traf-fic.Sixteen air traffic controllers were invited to participate real-time simulation experiments,during which the da-ta of their eye ball movements and air traffic were recorded.Tweny-three air traffic complexity metrics and six eye movements metrics were calculated to examine their relationships.Two correlational methods,Pearson′s correla-tion and Spearman′s correlation,were tested between every eye-traffic pair of metrics.The results indicate that controllers′two kinds of information-seeking behaviors can be identified from their eye movements:Targets track-ing,and confliction recognition.The study on controllers′eye movements may contribute to the understanding of information-seeking mechanisms leading to the development of more intelligent automations in the future.

  6. 40 CFR 2.306 - Special rules governing certain information obtained under the Toxic Substances Control Act.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Special rules governing certain information obtained under the Toxic Substances Control Act. 2.306 Section 2.306 Protection of Environment... distribution (including for test marketing purposes and for use in research and development), any...

  7. Auditing of sampling methods for air toxics at coal-fired power plants

    Energy Technology Data Exchange (ETDEWEB)

    Agbede, R.O.; Clements, J.L.; Grunebach, M.G. [Advanced Technology Systems, Inc., Monroeville, PA (United States)] [and others

    1995-11-01

    Advanced Technology Systems, Inc. (ATS) with subcontract assistance from international Technology Corporation (IT) has provided external audit activities for Phase II of the Department of Energy-Pittsburgh Energy Technology Center`s air emission test program. The objective of the audits is to help ensure that the data obtained from the emission tests are precise, accurate, representative, scientifically sound and legally defensible. This paper presents the criteria that were used to perform the external audits of the emission test program. It also describes the approach used by ATS and It in performing their audits. Examples of findings of the audits along with the actions take to correct problems and the subsequent effect of those actions on the test data are presented. The results of audit spikes performed at the Plant 1 test site are also discussed.

  8. Characterization of air toxics from a laboratory coal-fired combustor

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-03

    Emissions of hazardous air pollutants from coal combustion were studied in a laboratory-scale combustion facility, with emphasis on fine particles in three size ranges of less than 7.5 {mu}m diameter. Vapors were also measured. Substances under study included organic compounds, anions, elements, and radionuclides. Fly ash was generated by firing a bituminous coal in a combuster for 40 h at each of two coal feed rates. Flue gas was sampled under two conditions. Results for organic compounds, anions, and elements show a dependence on particle size consistent with published power plant data. Accumulation of material onto surface layers was inferred from differences in chemical composition between the plume simulating dilution sampler and hot flue samples. Extracts of organic particulate material were fractionated into different polarity fractions and analyzed by GC/MS. In Phase II, these laboratory results will be compared to emissions from a full-scale power plant burning the same coal.

  9. Benzene toxicity of the occurrence of benzene in the ambient air of the Houston area

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Y.C.

    1980-01-01

    This study was conducted by either literature review or actual field survey. Results are summarized as follows: (1) long-term occupational exposure of workers to benzene vapor at levels of 3 to 7 ppM, 2 to 3 ppM and 1.6 ppM may result in a decreased level of leucocyte alkaline phosphates, an increased incidence of chromosome aberrations and an increased level of ALA in erythrocytes, respectively; (2) benzene is capable of causing fetotoxic effects in animals at levels as low as 10 ppM by volume; (3) exposure of animals to or less than 1 ppM benzene vapor may result in leucopenia, an inverse ratio of muscle antagonist chronaxy and a decreased level of ascorbic acid in fetus's and mother's liver as well as whole embryo; (4) benzene is causally associated with the increased incidence of pancytopenia, including unicytopenia, bicytopenia and aplastic anemia, and chromosome aberrations in occupational exposure population, and at best benzene must also be considered as a leukemogen; (5) since it can be emitted into the atmosphere from both man-made and natural sources, benzene in some concentrations is presented everywhere in the various compartments of the environment; (6) the findings of the emission of benzene from certain natural sources indicate that reducing benzene to a zero-level of exposure is theoretically impossible; (7) the annual average of benzene concentration detected in the Houston ambient air is 2.50 ppB, which is about 2.4 times higher than the nation-wide annual average exposure level and may have some health implications to the general public; and (8) in the Houston area, stationary sources are more important than mobile sources in contributing to benzene in the ambient air.

  10. EPA Region 2 AIRS Aerometric Information Retrieval System and the Air Quality System (AIRS/AQS) GIS Layer

    Data.gov (United States)

    U.S. Environmental Protection Agency — This ArcGIS 10.2 point feature class contains identification, location and status information for EPA Region 2 facilities (NYS, NJ, Puerto Rico and the US Virgin...

  11. The US EPA Geographic Information System for mapping environmental releases of toxic chemical release inventory (TRI) chemicals

    Energy Technology Data Exchange (ETDEWEB)

    Stockwell, J.R.; Sorensen, J.W.; Eckert, J.W. Jr.; Carreras, E.M. (Environmental Protection Agency, Atlanta, GA (United States))

    1993-04-01

    This study characterizes the environmental releases of toxic chemicals of the Toxic Chemical Release Inventory (TRI) in the southeastern United States by using the US Environmental Protection Agency (EPA) Geographic Information System (GIS) to map them. These maps show that the largest quantities of TRI releases in the Southeast are usually near densely populated areas. This GIS mapping approach takes the first steps in defining those areas in the region which may be potential exposure zones and which could be strategic targets for future risk screening efforts in this geographic area. 8 refs., 6 figs., 1 tab.

  12. VOC and air toxics control using biofiltration: 2 full-scale system case studies

    Energy Technology Data Exchange (ETDEWEB)

    Fucich, W.J.; Togna, A.P.; Loudon, R.E. [Envirogen, Inc., Lawrenceville, NJ (United States)] [and others

    1997-12-31

    Industry continuous to search for innovative air treatment technologies to cost effectively meet the stringent requirements of the CAAA. High volume process exhaust streams contaminated with dilute concentrations of VOCs and HAPs are an especially challenging problem. Biological treatment is an option that must be evaluated with the traditional control technologies (chemical scrubbing, condensation, adsorption, thermal oxidation, etc.) because of the low operating costs and the system is environmentally friendly. In the United States, biofiltration is considered an emerging technology, however, full-scale biofiltration systems are now successfully operating in two rigorous services. At Nylonge Corporation, a biofilter is safely and efficiently degrading CS{sub 2} and H{sub 2}S vapor emissions. The ABTco system is successfully treating the target compounds, methanol and formaldehyde, in a press exhaust containing inert particulate and semi-volatiles. These systems are both based on a unique, patented modular design. The modular concept allows the system to be easily installed resulting in construction cost minimization and maintaining critical project schedules. The modular system offers flexibility because the biofilter is easily expanded to accommodate future plant growth. The modular design benefits the end user because individual modules or biofilter sections can be isolated for service and inspection while the biofilter system stays on-line. An up-flow configuration and the patented irrigation system allow biofilters to be used on the most difficult services. In the case of Nylonge, the biofilter is handling the sulfuric acid generated during the degradation of CS{sub 2} and H{sub 2}S vapors. At ABTco, stable operation is achieved in a stream containing particulates and semi-volatiles.

  13. The EUSTACE project: delivering global, daily information on surface air temperature

    Science.gov (United States)

    Morice, C. P.; Rayner, N. A.; Auchmann, R.; Bessembinder, J.; Bronnimann, S.; Brugnara, Y.; Conway, E. A.; Ghent, D.; Good, E.; Herring, K.; Kennedy, J.; Lindgren, F.; Madsen, K. S.; Merchant, C. J.; van der Schrier, G.; Stephens, A.; Tonboe, R. T.; Waterfall, A. M.; Mitchelson, J.; Woolway, I.

    2015-12-01

    Day-to-day variations in surface air temperature affect society in many ways; however, daily surface air temperature measurements are not available everywhere. A global daily analysis cannot be achieved with measurements made in situ alone, so incorporation of satellite retrievals is needed. To achieve this, we must develop an understanding of the relationships between traditional (land and marine) surface air temperature measurements and retrievals of surface skin temperature from satellite measurements, i.e. Land Surface Temperature, Ice Surface Temperature, Sea Surface Temperature and Lake Surface Water Temperature. These relationships can be derived either empirically or with the help of a physical model.Here we discuss the science needed to produce a fully-global daily analysis (or ensemble of analyses) of surface air temperature on the centennial scale, integrating different ground-based and satellite-borne data types. Information contained in the satellite retrievals would be used to create globally-complete fields in the past, using statistical models of how surface air temperature varies in a connected way from place to place. As the data volumes involved are considerable, such work needs to include development of new "Big Data" analysis methods.We will present plans and progress along this road in the EUSTACE project (2015-June 2018), i.e.: • providing new, consistent, multi-component estimates of uncertainty in surface skin temperature retrievals from satellites; • identifying inhomogeneities in daily surface air temperature measurement series from weather stations and correcting for these over Europe; • estimating surface air temperature over all surfaces of Earth from surface skin temperature retrievals; • using new statistical techniques to provide information on higher spatial and temporal scales than currently available, making optimum use of information in data-rich eras.Information will also be given on how interested users can become

  14. 78 FR 12052 - Agency Information Collection Activities: Proposed Collection; Comment Request; Ambient Air...

    Science.gov (United States)

    2013-02-21

    ... AGENCY Agency Information Collection Activities: Proposed Collection; Comment Request; Ambient Air... were approved under separate rulemaking actions: ICR 2358 (OMB 2060-0638) Nitrogen Oxides Ambient Monitoring ] ICR 2370 (OMB 2060-0642) Sulfur Dioxides Ambient Monitoring ICR 0940 (OMB 2060-0084) PM...

  15. Assessment of statin-associated muscle toxicity in Japan: a cohort study conducted using claims database and laboratory information

    OpenAIRE

    Chang, Chia-Hsien; Kusama, Makiko; Ono, Shunsuke; Sugiyama, Yuichi; Orii, Takao; Akazawa, Manabu

    2013-01-01

    Objective To estimate the incidence of muscle toxicity in patients receiving statin therapy by examining study populations, drug exposure status and outcome definitions. Design A retrospective cohort study. Setting 16 medical facilities in Japan providing information on laboratory tests performed in and claims received by their facilities between 1 April 2004 and 31 December 2010. Participants A database representing a cohort of 35 903 adult statin (atorvastatin, fluvastatin, pitavastatin, pr...

  16. Assessment of statin-associated muscle toxicity in Japan: a cohort study conducted using claims database and laboratory information

    Science.gov (United States)

    Chang, Chia-Hsien; Kusama, Makiko; Ono, Shunsuke; Sugiyama, Yuichi; Orii, Takao; Akazawa, Manabu

    2013-01-01

    Objective To estimate the incidence of muscle toxicity in patients receiving statin therapy by examining study populations, drug exposure status and outcome definitions. Design A retrospective cohort study. Setting 16 medical facilities in Japan providing information on laboratory tests performed in and claims received by their facilities between 1 April 2004 and 31 December 2010. Participants A database representing a cohort of 35 903 adult statin (atorvastatin, fluvastatin, pitavastatin, pravastatin, rosuvastatin and simvastatin) users was studied. Use of interacting drugs (fibrates, triazoles, macrolides, amiodarone and ciclosporin) by these patients was determined. Main outcome measure Statin-associated muscle toxicity (the ‘event’) was identified based on a diagnosis of muscle-related disorders (myopathy or rhabdomyolysis) and/or abnormal elevation of creatine kinase (CK) concentrations. Events were excluded if the patients had CK elevation-related conditions other than muscle toxicity. Incidence rates for muscle toxicity were determined per 1000 person-years, with 95% CI determined by Poisson regression. Results A total of 18 036 patients accounted for 42 193 person-years of statin therapy, and 43 events were identified. The incidence of muscle toxicity in the patients treated with statins was 1.02 (95% CI 0.76 to 1.37)/1000 person-years. The estimates varied when outcome definitions were modified from 0.09/1000 person-years, which met both diagnosis and CK 10× greater than the upper limit of normal range (ULN) criteria, to 2.06/1000 person-years, which met diagnosis or CK 5× ULN criterion. The incidence of muscle toxicity was also influenced by the statin therapies selected, but no significant differences were observed. Among 2430 patients (13.5%) received interacting drugs with statins, only three muscle toxicity cases were observed (incidence: 1.69/1000 person-years). Conclusions This database study suggested that statin use is generally well

  17. Component modeling in ecological risk assessment: Disturbance in interspecific interactions caused by air toxics introduced into terrestrial ecosystems

    Science.gov (United States)

    Swider, Jan Zenon

    Ecological Risk Assessment standpoint and examine the impact of air toxics emissions on an ecosystem, with particular emphasis on predator-prey interactions. Such analysis may help to identify the most likely conditions leading to the ecosystem instability and possibility of its recuperation.

  18. Analysis of air-toxics emissions, exposures, cancer risks, and controllability in five urban areas. Volume 1. Base year analysis and results

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, J.; Istvan, D.; Laich, E.; Lahre, T.

    1989-07-01

    This report is the first phase of a study to define the multiple-source, multiple pollutant nature of the urban air-toxics problem (also known as 'urban soup') and to discern what control measures (or combinations of measures) can best be employed to mitigate the urban air-toxics problem. The report documents the base year analysis, involving dispersion modeling of emissions data for 25 carcinogenic air toxics in five U.S. urban areas and a subsequent exposure/risk assessment to estimate aggregate cancer incidence. Aggregate (multi-source, multi-pollutant) cancer incidence (or population risk) across the 5 cities in this study averaged about 6 excess cases per million persons, ranging from about 2 to 10 in individual cities. The most-important pollutants contributing to aggregate incidence are polycyclic organic matter, 1,3-butadiene, formaldehyde and hexavalent chromium. The most-important sources are road vehicles, comfort and industrial cooling towers, chrome platers, solvent use, and fuel combustion, including wood stoves.

  19. Toxicity of copper oxide nanoparticles in lung epithelial cells exposed at the air-liquid interface compared with in vivo assessment.

    Science.gov (United States)

    Jing, Xuefang; Park, Jae Hong; Peters, Thomas M; Thorne, Peter S

    2015-04-01

    The toxicity of spark-generated copper oxide nanoparticles (CuONPs) was evaluated in human bronchial epithelial cells (HBEC) and lung adenocarcinoma cells (A549 cells) using an in vitro air-liquid interface (ALI) exposure system. Dose-response results were compared to in vivo inhalation and instillation studies of CuONPs. Cells were exposed to filtered, particle-free clean air (controls) or spark-generated CuONPs. The number median diameter, geometric standard deviation and total number concentration of CuONPs were 9.2 nm, 1.48 and 2.27×10(7)particles/cm(3), respectively. Outcome measures included cell viability, cytotoxicity, oxidative stress and proinflammatory chemokine production. Exposure to clean air (2 or 4h) did not induce toxicity in HBEC or A549 cells. Compared with controls, CuONP exposures significantly reduced cell viability, increased lactate dehydrogenase (LDH) release and elevated levels of reactive oxygen species (ROS) and IL-8 in a dose-dependent manner. A549 cells were significantly more susceptible to CuONP effects than HBEC. Antioxidant treatment reduced CuONP-induced cytotoxicity. When dose was expressed per area of exposed epithelium there was good agreement of toxicity measures with murine in vivo studies. This demonstrates that in vitro ALI studies can provide meaningful data on nanotoxicity of metal oxides.

  20. Monitoring of Pollution of Air Fine Particles (PM2.5) and Study on Their Genetic Toxicity

    Institute of Scientific and Technical Information of China (English)

    DONG-QUN XU; WEN-LI ZHANG

    2004-01-01

    To compare PM2.5 pollation level between the city of coal-fuel pollution (Taiyuan) and the city of pollution mixed with coal fuels and vehicle exhausts (Beijing), to analyze the concentration of B[a]p and Pb in the pollutants, and to study the DNA damage by PM2.5. Methods Air fine particles (PM2.5) were collected in Beijing and Taiyuan by means of the filter membrane method, the concentration of B[a]p and Pb were analyzed by high performance liquid chromatography and atomic absorption spectroscopy respectveily, and the damage of DNA by PM2.5 was detected by single cell gel-electrophoresis (SCGE) using the human lung epithelial cells (A549) as target cells. Results The concentration of PM2.5 in the winter of Beijing was 0.028-0.436 mg/m3, and that in Taiyuan was 0.132-0.681 mg/m3. The concentration of B[a]p was 0.104 and 0.156 μg/mg on PM2.5 of Beijing and Taiyuan, respectively, whereas the concentration of Pb was 1.094 and 1.137 μg/mg on PM2.5 of Beijing and Taiyuan, respectively. Exposure to PM2.5 at the concentrations of 5, 50, and 200 μg/mL for 12 h and 24 h caused DNA damage of the human alveolar epithelium, and the ratios of the tailing and length of the tail were all significantly different from those of the negative control group (P<0.05), and indicated a dose-response relationship. Conclusion PM2.5 has certain genetic toxicity.

  1. CREATION OF THE INFORMATIONAL MODEL OF TOXIC MYOCARDITIS OCCURRED UNDER THE INFLUENCE OF PESTICIDES

    Directory of Open Access Journals (Sweden)

    Sayora Akhmedova

    2015-12-01

    Full Text Available Creation of productive knowledge is important whereas on the base of this knowledge we can diagnose morphologic and morphometric properties of vascular stromal tissues of myocardium under toxic myocarditis on the bases of clinical symptoms. Consequence of this is a proper therapeutic strategy that will have a life importance for the patients.

  2. ToxPlorerTM: A Comprehensive Knowledgebase of Toxicity Pathways Using Ontology-driven Information Extraction

    Science.gov (United States)

    Realizing the potential of pathway-based toxicity testing requires a fresh look at how we describe phenomena leading to adverse effects in vivo, how we assess them in vitro and how we extrapolate them in silico across chemicals, doses and species. We developed the ToxPlorer™ fram...

  3. 76 FR 2677 - Request Facilities To Report Toxics Release Inventory Information Electronically or Complete Fill...

    Science.gov (United States)

    2011-01-14

    ... process TRI submissions and make valuable toxic chemical release and other waste management data available... codes other than SIC codes 20 through 39): 212111, 212112, 212113 (correspond to SIC 12, Coal Mining (except 1241)); 212221, 212222, 212231, 212234, 212299 (correspond to SIC 10, Metal Mining (except...

  4. Test results self-informativity properties annual dynamics of mean monthly air temperature anomalies

    Directory of Open Access Journals (Sweden)

    Nadezhda Aleksandrovna Vazhnova

    2016-11-01

    Full Text Available In this paper it is discussed the issues of methodology and the results of testing the possibilities of using the self- informatively properties in the series of the mean monthly air temperature anomalies (MMATA for the purposes of long-term forecasting of the thermal regime conditions on the example of Kazan Station, university. It is found that the prognostic informatively of the MMATA (for thermal conditions of July of the separately considered months is not statistically significant (missing since the previous June and in the earlier history, excluding the last 2 weeks of June, where the prognostic informatively is confirmed with the probability of ≥ 95%. The prognostic informatively of the mean monthly air temperature anomalies in relation to the thermal conditions of July rapidly increases with an increase in the accounted length of history of changes (preceding to the predicant in the mean monthly air temperature anomalies. It is shown that the filling of useful prognostic information takes place from April to June in relation to the conditions of Kazan. The accounting of self-informativity properties of the series of mean monthly air temperature anomalies has showed that the overall accuracy of the forecasts amounts to = 90%, at the general accuracy of random forecasts 0 = 74%, and at the methodical win = 16%. All these data suggest that the forecasts are at random level. Whereof we can conclude that the nonparametric discriminant analysis method is not always gives the positive results. Therefore, it is advisable to use more precise methods for the long-term weather forecasts, which give more acceptable forecast results with more accuracy.

  5. Insecticide toxicity to Hyalella curvispina in runoff and stream water within a soybean farm (Buenos Aires, Argentina).

    Science.gov (United States)

    Mugni, H; Ronco, A; Bonetto, C

    2011-03-01

    Toxicity to the locally dominant amphipod Hyalella curvispina was assessed in a first-order stream running through a cultivated farm. Cypermethrin, chlorpyrifos, endosulfan and glyphosate were sprayed throughout the studied period. Toxicity was assayed under controlled laboratory conditions with runoff and stream water samples taken from the field under steady state and flood conditions. Ephemeral toxicity pulses were observed as a consequence of farm pesticide applications. After pesticide application, runoff water showed 100% mortality to H. curvispina for 1 month, but no mortality thereafter. Toxicity persistence was shortest in stream water, intermediate in stream sediments and longest in soil samples. Runoff had a more important toxicity effect than the exposure to direct aerial fumigation. The regional environmental features determining fast toxicity dissipation are discussed.

  6. 77 FR 11145 - Intent to Request Renewal From OMB of One Current Public Collection of Information: Air Cargo...

    Science.gov (United States)

    2012-02-24

    ... Collection of Information: Air Cargo Security Requirements AGENCY: Transportation Security Administration...-cargo carriers. The collections of information that make up this ICR are security programs, security threat assessments (STA), known shipper data via the Known Shipper Management System (KSMS), Air...

  7. Comparison of immersed liquid and air cooling of NASA's Airborne Information Management System

    Science.gov (United States)

    Hoadley, A. W.; Porter, A. J.

    1992-01-01

    The Airborne Information Management System (AIMS) is currently under development at NASA Dryden Flight Research Facility. The AIMS is designed as a modular system utilizing surface mounted integrated circuits in a high-density configuration. To maintain the temperature of the integrated circuits within manufacturer's specifications, the modules are to be filled with Fluorinert FC-72. Unlike ground based liquid cooled computers, the extreme range of the ambient pressures experienced by the AIMS requires the FC-72 be contained in a closed system. This forces the latent heat absorbed during the boiling to be released during the condensation that must take within the closed module system. Natural convection and/or pumping carries the heat to the outer surface of the AIMS module where the heat transfers to the ambient air. This paper will present an evaluation of the relative effectiveness of immersed liquid cooling and air cooling of the Airborne Information Management System.

  8. A Framework of Environmental Modelling and Information Sharing for Urban Air Pollution Control and Management

    Institute of Scientific and Technical Information of China (English)

    LIU Gang-jun; FU Er-jiang; WANG Yun-jia; ZHANG Ke-fei; HAN Bao-ping; ARROWSMITH Colin

    2007-01-01

    More effective environmental pollution control and management are needed due to the increasing environmental impacts from a range of human activities and the growing public demands for a better living environment. Urban air pollution is a serious environmental issue that poses adverse impacts on the health of people and the environment in most metropolitan areas. In this paper, we propose a geoinformatics augmented framework of environmental modelling and information sharing for supporting effective urban air pollution control and management. This framework is outlined in terms of its key components and processes including: 1) an integrated, adaptive network of sensors for environmental monitoring; 2) a set of distributed, interoperable databases for data management; 3) a set of intelligent, robust algorithms and models for environmental modelling; 4) a set of flexible, efficient user interfaces for data access and information sharing; and 5) a reliable, high capacity, high performance computing and communication infrastructure for integrating and supporting other framework components and processes.

  9. Personnel Information Requirements for the Support of Air Force Squadron Commanders’ Information Systems

    Science.gov (United States)

    1989-12-01

    With Graphic Format Generated By A Squadron Commander Emlis+ed Monning 20 110 1807 C-198 or-ly Ju e o Feb 0p u c e 512S 1988 Jon Mar May JuI S;p Nv...I I 1988 Jon Mar’ Ma’y Jul Sep Nov Feb Apr Jun Rug Oci Dec Mo n th 61 Bibliography 1. Barros, Oscar. "Information Requirements And Alternatives In...14. Gruber , W.H. and J.S. Niles. The New Management. New York: McGraw-Hill, 1976. 15. Hughes, David. "MAC Command and Control Center To Serve As

  10. U.S. Air Force Scientific and Technical Information Program - The STINFO Program

    Science.gov (United States)

    Blados, Walter R.

    1991-01-01

    The U.S. Air Force STINFO (Scientific and Technical Information) program has as its main goal the proper use of all available scientific and technical information in the development of programs. The organization of STINFO databases, the use of STINFO in the development and advancement of aerospace science and technology and the acquisition of superior systems at lowest cost, and the application to public and private sectors of technologies developed for military uses are examined. STINFO user training is addressed. A project for aerospace knowledge diffusion is discussed.

  11. Understanding and Supporting Web Developers: Design and Evaluation of a Web Accessibility Information Resource (WebAIR).

    Science.gov (United States)

    Swallow, David; Petrie, Helen; Power, Christopher

    2016-01-01

    This paper describes the design and evaluation of a Web Accessibility Information Resource (WebAIR) for supporting web developers to create and evaluate accessible websites. WebAIR was designed with web developers in mind, recognising their current working practices and acknowledging their existing understanding of web accessibility. We conducted an evaluation with 32 professional web developers in which they used either WebAIR or an existing accessibility information resource, the Web Content Accessibility Guidelines, to identify accessibility problems. The findings indicate that several design decisions made in relation to the language, organisation, and volume of WebAIR were effective in supporting web developers to undertake web accessibility evaluations.

  12. CAirTOX: A compartment model for assessing the fate of and human exposure to toxic-chemical emissions to air

    Energy Technology Data Exchange (ETDEWEB)

    McKone, T.E.

    1993-10-01

    CAirTOX has been developed as a spreadsheet model to assist in making a risk assessment of toxic air emissions. With CAirTOX, one can address how contaminants released to an air basin can lead to contamination of soil, food, surface water, and sediments. The modeling effort includes a multimedia transport and transformation model, exposure scenario models, and efforts to quantify uncertainty in multimedia, multiple-pathway exposure assessments. The multimedia transport and transformation model is a steady-state, but non-equilibrium model that can be used to assess concentrations of contaminants released continuously to air. In Part 1, the authors describe the multimedia transport and transformation model used to determine the fate of air emissions. In Part 2, they describe inputs and data needs for CAirTOX and the development of a set of landscape factors, which can be used to represent regional air basin/water-shed systems in California. In Part 3, they describe the multiple-pathway exposure scenarios and exposure algorithms. In Part 4, they compare the HRA approach and results and the CAirTOX exposure equations. In Part 5, they consider model sensitivity and uncertainty to determine how variability and uncertainty in model inputs affects the precision, accuracy, and credibility of the model output.

  13. Air Toxics Under the Big Sky: examining the effectiveness of authentic scientific research on high school students' science skills and interest

    Science.gov (United States)

    Ward, Tony J.; Delaloye, Naomi; Adams, Earle Raymond; Ware, Desirae; Vanek, Diana; Knuth, Randy; Hester, Carolyn Laurie; Marra, Nancy Noel; Holian, Andrij

    2016-04-01

    Air Toxics Under the Big Sky is an environmental science outreach/education program that incorporates the Next Generation Science Standards (NGSS) 8 Practices with the goal of promoting knowledge and understanding of authentic scientific research in high school classrooms through air quality research. This research explored: (1) how the program affects student understanding of scientific inquiry and research and (2) how the open-inquiry learning opportunities provided by the program increase student interest in science as a career path. Treatment students received instruction related to air pollution (airborne particulate matter), associated health concerns, and training on how to operate air quality testing equipment. They then participated in a yearlong scientific research project in which they developed and tested hypotheses through research of their own design regarding the sources and concentrations of air pollution in their homes and communities. Results from an external evaluation revealed that treatment students developed a deeper understanding of scientific research than did comparison students, as measured by their ability to generate good hypotheses and research designs, and equally expressed an increased interest in pursuing a career in science. These results emphasize the value of and need for authentic science learning opportunities in the modern science classroom.

  14. AirNow Information Management System - Global Earth Observation System of Systems Data Processor for Real-Time Air Quality Data Products

    Science.gov (United States)

    Haderman, M.; Dye, T. S.; White, J. E.; Dickerson, P.; Pasch, A. N.; Miller, D. S.; Chan, A. C.

    2012-12-01

    Built upon the success of the U.S. Environmental Protection Agency's (EPA) AirNow program (www.AirNow.gov), the AirNow-International (AirNow-I) system contains an enhanced suite of software programs that process and quality control real-time air quality and environmental data and distribute customized maps, files, and data feeds. The goals of the AirNow-I program are similar to those of the successful U.S. program and include fostering the exchange of environmental data; making advances in air quality knowledge and applications; and building a community of people, organizations, and decision makers in environmental management. In 2010, Shanghai became the first city in China to run this state-of-the-art air quality data management and notification system. AirNow-I consists of a suite of modules (software programs and schedulers) centered on a database. One such module is the Information Management System (IMS), which can automatically produce maps and other data products through the use of GIS software to provide the most current air quality information to the public. Developed with Global Earth Observation System of Systems (GEOSS) interoperability in mind, IMS is based on non-proprietary standards, with preference to formal international standards. The system depends on data and information providers accepting and implementing a set of interoperability arrangements, including technical specifications for collecting, processing, storing, and disseminating shared data, metadata, and products. In particular, the specifications include standards for service-oriented architecture and web-based interfaces, such as a web mapping service (WMS), web coverage service (WCS), web feature service (WFS), sensor web services, and Really Simple Syndication (RSS) feeds. IMS is flexible, open, redundant, and modular. It also allows the merging of data grids to create complex grids that show comprehensive air quality conditions. For example, the AirNow Satellite Data Processor

  15. Development of the air module for the work information management system. Environmental subsystem (WIMS-ES). Master's thesis

    Energy Technology Data Exchange (ETDEWEB)

    Cantwell, R.A.; Davis, J.S.

    1992-09-01

    The primary objective of this research was to develop the air module for the Work Information Management System Environmental Subsystem (WIMSES). The air module will provide Air Force environmental managers with a management information system (MIS) to control the growing amount of air pollution data required to stay in compliance with the newly amended Clean Air Act. To develop the air module, the Air Force's air pollution management requirements were researched first. These requirements were then compared to the capabilities of existing air pollution MISs used in the Department of Defense, the Environmental Protection Agency, and in commercial industry. The research led to a draft air nodule that tracks a base's source inventory and associated permit, control equipment, and emission information. Each base's data will be fully accessible to headquarters personnel through the fully networked WIMS-ES. The draft air nodule was validated through an Air Staff review, an Air Force review, and finally, a workshop with Air Force air pollution experts. The finalized air module has been forwarded to the WIMS-ES programmers and will become the Air Force-wide air pollution MIS in early 1993.... Air pollution, Environmental management, Data management, Data bases, Management information systems, Information systems.

  16. Control of Toxic Chemicals in Puget Sound, Phase 3: Study of Atmospheric Deposition of Air Toxics to the Surface of Puget Sound

    Energy Technology Data Exchange (ETDEWEB)

    Brandenberger, Jill M.; Louchouarn, Patrick; Kuo, Li-Jung; Crecelius, Eric A.; Cullinan, Valerie I.; Gill, Gary A.; Garland, Charity R.; Williamson, J. B.; Dhammapala, R.

    2010-07-05

    The results of the Phase 1 Toxics Loading study suggested that runoff from the land surface and atmospheric deposition directly to marine waters have resulted in considerable loads of contaminants to Puget Sound (Hart Crowser et al. 2007). The limited data available for atmospheric deposition fluxes throughout Puget Sound was recognized as a significant data gap. Therefore, this study provided more recent or first reported atmospheric deposition fluxes of PAHs, PBDEs, and select trace elements for Puget Sound. Samples representing bulk atmospheric deposition were collected during 2008 and 2009 at seven stations around Puget Sound spanning from Padilla Bay south to Nisqually River including Hood Canal and the Straits of Juan de Fuca. Revised annual loading estimates for atmospheric deposition to the waters of Puget Sound were calculated for each of the toxics and demonstrated an overall decrease in the atmospheric loading estimates except for polybrominated diphenyl ethers (PBDEs) and total mercury (THg). The median atmospheric deposition flux of total PBDE (7.0 ng/m2/d) was higher than that of the Hart Crowser (2007) Phase 1 estimate (2.0 ng/m2/d). The THg was not significantly different from the original estimates. The median atmospheric deposition flux for pyrogenic PAHs (34.2 ng/m2/d; without TCB) shows a relatively narrow range across all stations (interquartile range: 21.2- 61.1 ng/m2/d) and shows no influence of season. The highest median fluxes for all parameters were measured at the industrial location in Tacoma and the lowest were recorded at the rural sites in Hood Canal and Sequim Bay. Finally, a semi-quantitative apportionment study permitted a first-order characterization of source inputs to the atmosphere of the Puget Sound. Both biomarker ratios and a principal component analysis confirmed regional data from the Puget Sound and Straits of Georgia region and pointed to the predominance of biomass and fossil fuel (mostly liquid petroleum products such

  17. 75 FR 63192 - Intent To Request Renewal From OMB of One Current Public Collection of Information: Air Cargo...

    Science.gov (United States)

    2010-10-14

    ... Collection of Information: Air Cargo Security Requirements AGENCY: Transportation Security Administration... under a security program, and all-cargo carriers: Security programs, security threat assessments (STA), known shipper data via the Known Shipper Management System (KSMS), cargo screening reporting,...

  18. Egg incubation position affects toxicity of air cell administered PCB 126 (3,3?4,4?,5- pentachlorobiphenyl) in chicken (Gallus domesticus) embryos

    Science.gov (United States)

    McKernan, M.A.; Rattner, B.A.; Hale, R.C.; Ottinger, M.A.

    2007-01-01

    The avian egg is used extensively for chemical screening and determining the relative sensitivity of species to environmental contaminants (e.g., metals, pesticides, polyhalogenated compounds). The effect of egg incubation position on embryonic survival, pipping, and hatching success was examined following air cell administration of polychlorinated biphenyl (PCB) congener 126 (3,3',4,4',5-pentachlorobiphenyl [PCB 126]; 500?2,000 pg/g egg) on day 4 of development in fertile chicken (Gallus gallus) eggs. Depending on dose, toxicity was found to be up to nine times greater in vertically versus horizontally incubated eggs. This may be due to enhanced embryonic exposure to the injection bolus in vertically incubated eggs compared to more gradual uptake in horizontally incubated eggs. Following air cell administration of PCB 126, horizontal incubation of eggs may more closely approximate uptake and toxicity that has been observed with naturally incorporated contaminants. These data have implications for chemical screening and use of laboratory data for ecological risk assessments.

  19. Analysis of Air Toxics From NOAA WP-3 Aircraft Measurements During the TexAQS 2006 Campaign: Comparison With Emission Inventories and Additive Inhalation Risk Factors

    Science.gov (United States)

    Del Negro, L. A.; Warneke, C.; de Gouw, J. A.; Atlas, E.; Lueb, R.; Zhu, X.; Pope, L.; Schauffler, S.; Hendershot, R.; Washenfelder, R.; Fried, A.; Richter, D.; Walega, J. G.; Weibring, P.

    2007-12-01

    Benzene and nine other air toxics classified as human carcinogens by the International Agency for Research on Cancer (IARC) were measured from the NOAA WP-3 aircraft during the TexAQS 2006 campaign. In-situ measurements of benzene, measured with a PTR-MS instrument, are used to estimate emission fluxes for comparison with point source emission inventories developed by the Texas Commission on Environmental Quality. Mean and median mixing ratios for benzene, acetaldehyde, formaldehyde, 1,3-butadiene, carbon tetrachloride, chloroform, 1,2-dichloroethane, dibromoethane, dichloromethane, and vinyl chloride, encountered over the city of Houston during the campaign, are combined with inhalation unit risk factor values developed by the California Environmental Protection Agency and the United States Environmental Protection Agency to estimate the additive inhalation risk factor. This additive risk factor represents the risk associated with lifetime (70 year) exposure at the levels measured and should not be used as an absolute indicator of risk to individuals. However, the results are useful for assessments of changing relative risk over time, and for identifying dominant contributions to the overall air toxic risk.

  20. Use of Segregation Indices, Townsend Index, and Air Toxics Data to Assess Lifetime Cancer Risk Disparities in Metropolitan Charleston, South Carolina, USA

    Directory of Open Access Journals (Sweden)

    LaShanta J. Rice

    2014-05-01

    Full Text Available Background: Studies have demonstrated a relationship between segregation and level of education, occupational opportunities, and risk behaviors, yet a paucity of research has elucidated the association between racial residential segregation, socioeconomic deprivation, and lifetime cancer risk. Objectives: We examined estimated lifetime cancer risk from air toxics by racial composition, segregation, and deprivation in census tracts in Metropolitan Charleston. Methods: Segregation indices were used to measure the distribution of groups of people from different races within neighborhoods. The Townsend Index was used to measure economic deprivation in the study area. Poisson multivariate regressions were applied to assess the association of lifetime cancer risk with segregation indices and Townsend Index along with several sociodemographic measures. Results: Lifetime cancer risk from all pollution sources was 28 persons/million for half of the census tracts in Metropolitan Charleston. Isolation Index and Townsend Index both showed significant correlation with lifetime cancer risk from different sources. This significance still holds after adjusting for other sociodemographic measures in a Poisson regression, and these two indices have stronger effect on lifetime cancer risk compared to the effects of sociodemographic measures. Conclusions: We found that material deprivation, measured by the Townsend Index and segregation measured by the Isolation index, introduced high impact on lifetime cancer risk by air toxics at the census tract level.

  1. Toxicity tests and sediment chemistry at Site 9 (Neptune Drive Disposal Site) - U.S. Naval Air Station, Brunswick, Maine

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — During a remedial investigation of the U.S. Naval Air Station Superfund Site in Brunswick, Maine (NASB), elevated concentrations of total polycyclic aromatic...

  2. Air exchange rates and alternative vapor entry pathways to inform vapor intrusion exposure risk assessments.

    Science.gov (United States)

    Reichman, Rivka; Roghani, Mohammadyousef; Willett, Evan J; Shirazi, Elham; Pennell, Kelly G

    2016-11-12

    Vapor intrusion (VI) is a term used to describe indoor air (IA) contamination that occurs due to the migration of chemical vapors in the soil and groundwater. The overall vapor transport process depends on several factors such as contaminant source characteristics, subsurface conditions, building characteristics, and general site conditions. However, the classic VI conceptual model does not adequately account for the physics of airflow around and inside a building and does not account for chemical emissions from alternative "preferential" pathways (e.g. sewers and other utility connections) into IA spaces. This mini-review provides information about recent research related to building air exchange rates (AERs) and alternative pathways to improve the accuracy of VI exposure risk assessment practices. First, results from a recently published AER study for residential homes across the United States (US) are presented and compared to AERs recommended by the US Environmental Protection Agency (USEPA). The comparison shows considerable differences in AERs when season, location, building age, and other factors are considered. These differences could directly impact VI assessments by influencing IA concentration measurements. Second, a conceptual model for sewer gas entry into buildings is presented and a summary of published field studies is reported. The results of the field studies suggest that alternative pathways for vapors to enter indoor spaces warrant consideration. Ultimately, the information presented in this mini-review can be incorporated into a multiple-lines-of-evidence approach for assessing site-specific VI exposure risks.

  3. Air pollution from household solid fuel combustion in India: an overview of exposure and health related information to inform health research priorities.

    Science.gov (United States)

    Balakrishnan, Kalpana; Ramaswamy, Padmavathi; Sambandam, Sankar; Thangavel, Gurusamy; Ghosh, Santu; Johnson, Priscilla; Mukhopadhyay, Krishnendu; Venugopal, Vidhya; Thanasekaraan, Vijayalakshmi

    2011-01-01

    Environmental and occupational risk factors contribute to nearly 40% of the national burden of disease in India, with air pollution in the indoor and outdoor environment ranking amongst leading risk factors. It is now recognized that the health burden from air pollution exposures that primarily occur in the rural indoors, from pollutants released during the incomplete combustion of solid fuels in households, may rival or even exceed the burden attributable to urban outdoor exposures. Few environmental epidemiological efforts have been devoted to this setting, however. We provide an overview of important available information on exposures and health effects related to household solid fuel use in India, with a view to inform health research priorities for household air pollution and facilitate being able to address air pollution within an integrated rural-urban framework in the future.

  4. 19 CFR 103.31a - Advance electronic information for air, truck, and rail cargo; Importer Security Filing...

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Advance electronic information for air, truck, and rail cargo; Importer Security Filing information for vessel cargo. 103.31a Section 103.31a Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE...

  5. Resources for global risk assessment: the International Toxicity Estimates for Risk (ITER) and Risk Information Exchange (RiskIE) databases.

    Science.gov (United States)

    Wullenweber, Andrea; Kroner, Oliver; Kohrman, Melissa; Maier, Andrew; Dourson, Michael; Rak, Andrew; Wexler, Philip; Tomljanovic, Chuck

    2008-11-15

    The rate of chemical synthesis and use has outpaced the development of risk values and the resolution of risk assessment methodology questions. In addition, available risk values derived by different organizations may vary due to scientific judgments, mission of the organization, or use of more recently published data. Further, each organization derives values for a unique chemical list so it can be challenging to locate data on a given chemical. Two Internet resources are available to address these issues. First, the International Toxicity Estimates for Risk (ITER) database (www.tera.org/iter) provides chronic human health risk assessment data from a variety of organizations worldwide in a side-by-side format, explains differences in risk values derived by different organizations, and links directly to each organization's website for more detailed information. It is also the only database that includes risk information from independent parties whose risk values have undergone independent peer review. Second, the Risk Information Exchange (RiskIE) is a database of in progress chemical risk assessment work, and includes non-chemical information related to human health risk assessment, such as training modules, white papers and risk documents. RiskIE is available at http://www.allianceforrisk.org/RiskIE.htm, and will join ITER on National Library of Medicine's TOXNET (http://toxnet.nlm.nih.gov/). Together, ITER and RiskIE provide risk assessors essential tools for easily identifying and comparing available risk data, for sharing in progress assessments, and for enhancing interaction among risk assessment groups to decrease duplication of effort and to harmonize risk assessment procedures across organizations.

  6. New Directions: GEIA’s 2020 Vision for Better Air Emissions Information

    Energy Technology Data Exchange (ETDEWEB)

    Frost, G. J.; Middleton, Paulette; Tarrason, Leonor; Granier, Claire; Guenther, Alex B.; Cardenas, B.; Denier van der Gon, Hugo; Janssens-Maenhout, Greet; Kaiser, Johannes W.; Keating, Terry; Klimont, Z.; Lamarque, Jean-Francois; Liousse, Catherine; Nickovic, S.; Ohara, Toshimasa; Schultz, Martin; Skiba, Ute; Wang, Y.

    2013-12-01

    We are witnessing a crucial change in how we quantify and understand emissions of greenhouse gases and air pollutants, with an increasing demand for science-based transparent emissions information produced by robust community efforts. Today’s scientific capabilities, with near-real-time in-situ and remote sensing observations combined with forward and inverse models and a better understanding of the controlling processes, are contributing to this transformation and providing new approaches to derive, verify, and forecast emissions (Tong et al., 2011; Frost et al., 2012) and to quantify their impacts on the environment (e.g., Bond et al., 2013). At the same time, the needs for emissions information and the demands for their accuracy and consistency have grown. Changing economies, demographics, agricultural practices, and energy sources, along with mandates to evaluate emissions mitigation efforts, demonstrate compliance with legislation, and verify treaties, are leading to new challenges in emissions understanding. To quote NOAA Senior Technical Scientist David Fahey, "We are in the Century of Accountability. Emissions information is critical not only for environmental science and decision-making, but also as an instrument of foreign policy and international diplomacy." Emissions quantification represents a key step in explaining observed variability and trends in atmospheric composition and in attributing these observed changes to their causes. Accurate emissions data are necessary to identify feasible controls that reduce adverse impacts associated with air quality and climate and to track the success of implemented policies. To progress further, the international community must improve the understanding of drivers and contributing factors to emissions, and it must strengthen connections among and within different scientific disciplines that characterize our environment and entities that protect the environment and influence further emissions. The Global

  7. Differential neural network approach in information process for prediction of roadside air pollution by peat fire

    Science.gov (United States)

    Lozhkin, V.; Tarkhov, D.; Timofeev, V.; Lozhkina, O.; Vasilyev, A.

    2016-11-01

    The paper presents a novel differential neural network model estimating the dispersion of CO emissions from a peat fire near a highway. We have developed approaches for the optimization of the model on the base of simulated and experimental measurements of CO concentrations in the area of dispersion of the smoke cloud. The numerical solutions of the problem are presented in the form of neural network approximations by the Gaussian model and in the form of neural network approximate solutions of partial differential equations. The trained neural network model can be used for the prediction of emergency when wind speed and direction and other fire parameters are changing. The method is also recommended for the development of air quality monitoring and predicting information systems.

  8. Fact Sheets: Final Rule to Reduce Toxic Air Pollutants from Printing, Coating, and Dyeing of Fabrics and Other Textiles

    Science.gov (United States)

    This page contains the February 2003 and the October 2004 final rule fact sheet that contain information on the NESHAP for Printing, Coating, and Dyeing of Fabrics and Other Textiles. These documents provide a summary of the information for this NESHAP.

  9. Role of ureogenesis in tackling problems of ammonia toxicity during exposure to higher ambient ammonia in the air-breathing walking catfish Clarias batrachus

    Indian Academy of Sciences (India)

    Nirmalendu Saha; Shritapa Datta; Kuheli Biswas; Zaiba Y Kharbuli

    2003-12-01

    In the present study, the possible role of ureogenesis to avoid the accumulation of toxic ammonia to a lethal level under hyper-ammonia stress was tested in the air-breathing walking catfish Clarias batrachus by exposing the fish at 25 mM NH4Cl for 7 days. Excretion of ammonia by the NH4Cl-exposed fish was totally suppressed, which was accompanied by significant accumulation of ammonia in different body tissues. The walking catfish, which is otherwise predominantly ammoniotelic, turned totally towards ureotelism from ammoniotelism with a 5- to 6-fold increase of urea-N excretion during exposure to higher ambient ammonia. Stimulation of ureogenesis was accompanied with significant increase of some of the key urea cycle enzymes such as carbamyl phosphate synthetase (urea cycle-related), argininosuccinate synthetase and argininosuccinate lyase both in hepatic and non-hepatic tissues. Due to this unique physiological strategy of turning towards ureotelism from ammoniotelism via the induced urea cycle, this air-breathing catfish is able to survive in very high ambient ammonia, which they face in certain seasons of the year in the natural habitat.

  10. The Global Framework for Providing Information about Volcanic-Ash Hazards to International Air Navigation

    Science.gov (United States)

    Romero, R. W.; Guffanti, M.

    2009-12-01

    The International Civil Aviation Organization (ICAO) created the International Airways Volcano Watch (IAVW) in 1987 to establish a requirement for international dissemination of information about airborne ash hazards to safe air navigation. The IAVW is a set of operational protocols and guidelines that member countries agree to follow in order to implement a global, multi-faceted program to support the strategy of ash-cloud avoidance. Under the IAVW, the elements of eruption reporting, ash-cloud detecting, and forecasting expected cloud dispersion are coordinated to culminate in warnings sent to air traffic controllers, dispatchers, and pilots about the whereabouts of ash clouds. Nine worldwide Volcanic Ash Advisory Centers (VAAC) established under the IAVW have the responsibility for detecting the presence of ash in the atmosphere, primarily by looking at imagery from civilian meteorological satellites, and providing advisories about the location and movement of ash clouds to aviation meteorological offices and other aviation users. Volcano Observatories also are a vital part of the IAVW, as evidenced by the recent introduction of a universal message format for reporting the status of volcanic activity, including precursory unrest, to aviation users. Since 2003, the IAVW has been overseen by a standing group of scientific, technical, and regulatory experts that assists ICAO in the development of standards and other regulatory material related to volcanic ash. Some specific problems related to the implementation of the IAVW include: the lack of implementation of SIGMET (warning to aircraft in flight) provisions and delayed notifications of volcanic eruptions. Expected future challenges and developments involve the improvement in early notifications of volcanic eruptions, the consolidation of the issuance of SIGMETs, and the possibility of determining a “safe” concentration of volcanic ash.

  11. Notice of Construction (NOC) Application for Criteria and Toxic Air Pollutant Emissions from Thermal Stabilization of Polycubes at the PFP

    Energy Technology Data Exchange (ETDEWEB)

    RANADE, D.G.

    2000-11-01

    This is a notice of construction (NOC) application for thermal stabilization of plutonium in a polystyrene matrix (polycubes) in the muffle furnaces at the Plutonium Finishing Plant (PFP). This NOC application is required by Washington Administrative Code (WAC) 173-460-040. During the 1960's and 1970's, polycubes were thermally stabilized using a pyrolysis process at PFP. The proposed process of thermal stabilization of polycubes in muffle furnaces results in emissions of air contaminants not emitted since implementation of WAC 173-460 (effective 9/18/91). The new process and related air contaminants are the basis for this NOC application. The proposed activity would use the muffle furnaces in the 234-52 Building to stabilize polycubes. The resulting plutonium oxides would be packaged to meet storage requirements specified in Stabilization, Packaging, and Storage of Plutonium Bearing Materials (DOE-STD-3013). The PFP is located in the 200 West Area of the Hanford Site. The PFP consists of several large and small buildings that are grouped to form the processing complex. The PFP activities are focused on the stabilization of plutonium-bearing materials to a form suitable for long-term storage; immobilization of residual plutonium-bearing materials; and removal of readily retrievable, plutonium-bearing materials left behind in process equipment and process areas.

  12. Toxicity of Exhaust Gases and Particles from IC-Engines – International Activities Survey (EngToxIn). 2nd Information Report for IEA Implementing Agreement AMF

    Energy Technology Data Exchange (ETDEWEB)

    Czerwinski, J. [University for Applied Sciences, Biel-Bienne (Switzerland)

    2012-10-15

    Exhaust gases from engines, as well as from other technical combustion processes contain gaseous, semi volatile and solid compounds which are toxic. Some of these compounds are not yet limited by the respective legislations; but may need to be based on ongoing health research findings and some new substances did appear recently, due to the progressing technical developments providing new systems of exhaust gas aftertreatment. A new approach described here is that the toxic effects of exhaust gases as an aerosol containing gaseous components as well as particulate matter and nanoparticles can be investigated in a global way, by exposing the living cells, or cell cultures to the aerosol, which means a simultaneous superposition of all toxic effects from all active components. At several research sites it has been showed, that this method offers more objective results of validation of toxicity, than other methods used until now. It also enables a relatively quick insight in the toxic effects with consideration of all superimposed influences of the aerosol. This new methodology can be applied for all kinds of emission sources. It also bears the potential of giving new contributions to the present state of knowledge in this domain and can in some cases lead to a change of paradigma. The present report gives information about activities concerning the research on toxicity of exhaust gases from IC-engines in different countries. It also gives some ideas about the available information sources. The general situation and the basic information have not changed much so the chapters 1 and 2 are repeated from the last year report, [1] with only a few modifications. We observe fast increasing research activities concerning health effects worldwide. They have different objectives, different approaches and methodologies and sometimes the results can be directly compared to each other. There are mostly common lines and with appropriate efforts there might be possible ways to

  13. Applications of the three-dimensional air quality system to western U.S. air quality: IDEA, smog blog, smog stories, airquest, and the remote sensing information gateway.

    Science.gov (United States)

    Hoff, Raymond; Zhang, Hai; Jordan, Nikisa; Prados, Ana; Engel-Cox, Jill; Huff, Amy; Weber, Stephanie; Zell, Erica; Kondragunta, Shobha; Szykman, James; Johns, Brad; Dimmick, Fred; Wimmers, Anthony; Al-Saadi, Jay; Kittaka, Chieko

    2009-08-01

    A system has been developed to combine remote sensing and ground-based measurements of aerosol concentration and aerosol light scattering parameters into a three-dimensional view of the atmosphere over the United States. Utilizing passive and active remote sensors from space and the ground, the system provides tools to visualize particulate air pollution in near real time and archive the results for retrospective analyses. The main components of the system (Infusing satellite Data into Environmental Applications [IDEA], the U.S. Air Quality Weblog [Smog Blog], Smog Stories, U.S. Environmental Protection Agency's AIRQuest decision support system, and the Remote Sensing Information Gateway [RSIG]) are described, and the relationship of how data move from one system to another is outlined. To provide examples of how the results can be used to analyze specific pollution episodes, three events (two fires and one wintertime low planetary boundary layer haze) are discussed. Not all tools are useful at all times, and the limitations, including the sparsity of some data, the interference caused by overlying clouds, etc., are shown. Nevertheless, multiple sources of data help a state, local, or regional air quality analyst construct a more thorough picture of a daily air pollution situation than what one would obtain with only surface-based sensors.

  14. What Health-Related Information Flows through You Every Day? A Content Analysis of Microblog Messages on Air Pollution

    Science.gov (United States)

    Yang, Qinghua; Yang, Fan; Zhou, Chun

    2015-01-01

    Purpose: The purpose of this paper is to investigate how the information about haze, a term used in China to describe the air pollution problem, is portrayed on Chinese social media by different types of organizations using the theoretical framework of the health belief model (HBM). Design/methodology/approach: A content analysis was conducted…

  15. Defensive Information Operations in Support of the Marine Air Ground Task Force

    Science.gov (United States)

    2007-11-02

    Report INFOSEC Information Security INFOSYS Information Systems IO Information Operations ISMO Information Systems Management Office...scanning software. “ Much of the success of the Information Systems Management Office ( ISMO ) team comes from educating the Marines on these dangers and

  16. Communications System Architecture Development for Air Traffic Management and Aviation Weather Information Dissemination

    Science.gov (United States)

    Gallagher, Seana; Olson, Matt; Blythe, Doug; Heletz, Jacob; Hamilton, Griff; Kolb, Bill; Homans, Al; Zemrowski, Ken; Decker, Steve; Tegge, Cindy

    2000-01-01

    This document is the NASA AATT Task Order 24 Final Report. NASA Research Task Order 24 calls for the development of eleven distinct task reports. Each task was a necessary exercise in the development of comprehensive communications systems architecture (CSA) for air traffic management and aviation weather information dissemination for 2015, the definition of the interim architecture for 2007, and the transition plan to achieve the desired End State. The eleven tasks are summarized along with the associated Task Order reference. The output of each task was an individual task report. The task reports that make up the main body of this document include Task 5, Task 6, Task 7, Task 8, Task 10, and Task 11. The other tasks provide the supporting detail used in the development of the architecture. These reports are included in the appendices. The detailed user needs, functional communications requirements and engineering requirements associated with Tasks 1, 2, and 3 have been put into a relational database and are provided electronically.

  17. Accuracy and reliability of Chile's National Air Quality Information System for measuring particulate matter: Beta attenuation monitoring issue.

    Science.gov (United States)

    Toro A, Richard; Campos, Claudia; Molina, Carolina; Morales S, Raul G E; Leiva-Guzmán, Manuel A

    2015-09-01

    A critical analysis of Chile's National Air Quality Information System (NAQIS) is presented, focusing on particulate matter (PM) measurement. This paper examines the complexity, availability and reliability of monitoring station information, the implementation of control systems, the quality assurance protocols of the monitoring station data and the reliability of the measurement systems in areas highly polluted by particulate matter. From information available on the NAQIS website, it is possible to confirm that the PM2.5 (PM10) data available on the site correspond to 30.8% (69.2%) of the total information available from the monitoring stations. There is a lack of information regarding the measurement systems used to quantify air pollutants, most of the available data registers contain gaps, almost all of the information is categorized as "preliminary information" and neither standard operating procedures (operational and validation) nor assurance audits or quality control of the measurements are reported. In contrast, events that cause saturation of the monitoring detectors located in northern and southern Chile have been observed using beta attenuation monitoring. In these cases, it can only be concluded that the PM content is equal to or greater than the saturation concentration registered by the monitors and that the air quality indexes obtained from these measurements are underestimated. This occurrence has been observed in 12 (20) public and private stations where PM2.5 (PM10) is measured. The shortcomings of the NAQIS data have important repercussions for the conclusions obtained from the data and for how the data are used. However, these issues represent opportunities for improving the system to widen its use, incorporate comparison protocols between equipment, install new stations and standardize the control system and quality assurance.

  18. The impact of communicating information about air pollution events on public health.

    Science.gov (United States)

    McLaren, J; Williams, I D

    2015-12-15

    Short-term exposure to air pollution has been associated with exacerbation of asthma and chronic obstructive pulmonary disease (COPD). This study investigated the relationship between emergency hospital admissions for asthma, COPD and episodes of poor air quality in an English city (Southampton) from 2008-2013. The city's council provides a forecasting service for poor air quality to individuals with respiratory disease to reduce preventable admissions to hospital and this has been evaluated. Trends in nitrogen dioxide, ozone and particulate matter concentrations were related to hospital admissions data using regression analysis. The impacts of air quality on emergency admissions were quantified using the relative risks associated with each pollutant. Seasonal and weekly trends were apparent for both air pollution and hospital admissions, although there was a weak relationship between the two. The air quality forecasting service proved ineffective at reducing hospital admissions. Improvements to the health forecasting service are necessary to protect the health of susceptible individuals, as there is likely to be an increasing need for such services in the future.

  19. Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis : Are Drug Dictionaries Correctly Informing Physicians Regarding the Risk?

    NARCIS (Netherlands)

    Haddad, Cynthia; Sidoroff, Alexis; Kardaun, Sylvia H.; Mockenhaupt, Maja; Creamer, Daniel; Dunant, Ariane; Roujeau, Jean-Claude

    2013-01-01

    Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) are severe drug reactions associated with high mortality and multiple incapacitating sequelae. In the past 20 years, two large multinational case control studies, published in 1995 and 2008, had identified different degrees of drug associ

  20. Impact analysis of traffic-related air pollution based on real-time traffic and basic meteorological information.

    Science.gov (United States)

    Pan, Long; Yao, Enjian; Yang, Yang

    2016-12-01

    With the rapid development of urbanization and motorization in China, traffic-related air pollution has become a major component of air pollution which constantly jeopardizes public health. This study proposes an integrated framework for estimating the concentration of traffic-related air pollution with real-time traffic and basic meteorological information and also for further evaluating the impact of traffic-related air pollution. First, based on the vehicle emission factor models sensitive to traffic status, traffic emissions are calculated according to the real-time link-based average traffic speed, traffic volume, and vehicular fleet composition. Then, based on differences in meteorological conditions, traffic pollution sources are divided into line sources and point sources, and the corresponding methods to determine the dynamic affecting areas are also proposed. Subsequently, with basic meteorological data, Gaussian dispersion model and puff integration model are applied respectively to estimate the concentration of traffic-related air pollution. Finally, the proposed estimating framework is applied to calculate the distribution of CO concentration in the main area of Beijing, and the population exposure is also calculated to evaluate the impact of traffic-related air pollution on public health. Results show that there is a certain correlation between traffic indicators (i.e., traffic speed and traffic intensity) of the affecting area and traffic-related CO concentration of the target grid, which indicates the methods to determine the affecting areas are reliable. Furthermore, the reliability of the proposed estimating framework is verified by comparing the predicted and the observed ambient CO concentration. In addition, results also show that the traffic-related CO concentration is higher in morning and evening peak hours, and has a heavier impact on public health within the Fourth Ring Road of Beijing due to higher population density and higher CO

  1. 30 CFR 250.249 - What air emissions information must accompany the DPP or DOCD?

    Science.gov (United States)

    2010-07-01

    ... when applicable, nitrogen oxides (NOX), carbon monoxide (CO), and volatile organic compounds (VOC) that....303(d). When MMS requires air quality modeling, you must use the guidelines in Appendix W of 40 CFR... data consistent with the model(s) used. (f) Modeling report. A modeling report or the modeling...

  2. Advanced Crash Survivable Flight Data Recorder And Accident Information Retrieval System (AIRS).

    Science.gov (United States)

    1981-08-01

    95 31 NARROW-BAND CONDUCTED EMISSIONS ON THE AIRS 24 VDC POWER RETURN (CE04 TESI ) ......................... 96 32 BROAD-BAND...three layers of vulcanized synthetic rubber containing an intumescent ceramic material and includes a wire mesh reinforcement between the outermost

  3. Clean Air Act: Confidential business information security manual (revised). Procedures manual

    Energy Technology Data Exchange (ETDEWEB)

    Toomer, M.W.

    1998-08-01

    The procedures in this manual provide Federal, contractor, and subcontractor employees with the information necessary to utilize Confidential Business Information to perform their assigned duties without violating applicable Federal regulations protecting the rights of its owners.

  4. Information draft on the development of air standards for n-heptane

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-01-01

    Heptane is a colourless, volatile, flammable liquid with nine isomers, the most common being n-heptane, which has a paraffinic odour. It is an ingredient in gasoline, rubber solvents, naphtha and other petroleum solvents. It occurs almost entirely in the vapour phase, where it is degraded primarily by reaction with photochemically-produced hydroxyl radicals. Short-term exposure to n-heptane at relatively low concentration resulted in vertigo and loss of coordination. Exposure to high concentration for less than 40 minutes induced prostration and loss of reflexes prior to convulsion and death. Average ambient air concentration for n-heptane in Ontario between 1988 and 1995 was 0.81 microgram/cubic meter, as measured by Environment Canada. Currently, Ontario does not have air quality criterion for n-heptane. A review of pertinent literature from world-wide sources revealed that only the states of Michigan and New York have developed air quality guidelines specifically for n-heptane, based on occupational exposure. No human or animal data was found to be available to assess the carcinogenicity of this compound. 33 refs., 1 tab., appendix.

  5. Airborne Use of Traffic Intent Information in a Distributed Air-Ground Traffic Management Concept: Experiment Design and Preliminary Results

    Science.gov (United States)

    Wing, David J.; Adams, Richard J.; Barmore, Bryan E.; Moses, Donald

    2002-01-01

    This paper presents initial findings of a research study designed to provide insight into the issue of intent information exchange in constrained en-route air-traffic operations and its effect on pilot decision making and flight performance. The piloted simulation was conducted in the Air Traffic Operations Laboratory at the NASA Langley Research Center. Two operational modes for autonomous operations were compared under conditions of low and high operational complexity. The tactical mode was characterized primarily by the use of state information for conflict detection and resolution and an open-loop means for the pilot to meet operational constraints. The strategic mode involved the combined use of state and intent information, provided the pilot an additional level of alerting, and allowed a closed-loop approach to meeting operational constraints. Operational constraints included separation assurance, schedule adherence, airspace hazard avoidance, flight efficiency, and passenger comfort. Potential operational benefits of both modes are illustrated through several scenario case studies. Subjective pilot ratings and comments comparing the tactical and strategic modes are presented.

  6. AirData

    Data.gov (United States)

    U.S. Environmental Protection Agency — The AirData site provides access to yearly summaries of United States air pollution data, taken from EPA's air pollution databases. AirData has information about...

  7. The Many Faces of Information Management. AIR 1998 Annual Forum Paper.

    Science.gov (United States)

    Krotseng, Marsha V.; McLaughlin, Gerald W.

    This paper examines the many facets of administrative information management on the college or university campus. It is argued that, depending on the situation, an effective information manager can adopt the outlook of an architect/designer, data administrator, editor, analyst, reporter, planner, broker, collaborator, interpreter, or marketer.…

  8. 78 FR 25352 - Agency Information Collection; Activity Under OMB Review; Preservation of Air carrier Records

    Science.gov (United States)

    2013-04-30

    ... commissions received by, paid to, or deducted by travel agents, and all statements, invoices, bills and... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Research & Innovative Technology Administration Agency Information Collection; Activity Under OMB...

  9. Toxics Release Inventory (TRI)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Toxics Release Inventory (TRI) is a dataset compiled by the U.S. Environmental Protection Agency (EPA). It contains information on the release and waste...

  10. The Impact of New Electronic Imaging Systems on U.S. Air Force Visual Information Professionals.

    Science.gov (United States)

    1993-06-01

    Tekcvvxunikatn Tcmo= Max 85287-1305 (602) %55011 FROM: Maj Lee E. Thomas 20 Jan 1993 2336 W. Nopal Ave. Mesa, AZ 85202 (602) 820-5213 SUBJECT: Request for...Visual Information (VI) Personnel Requestor Information: Major Lee E. Thomas 2336 W. Nopal Ave. Mesa, AZ 85202 Ph: (602) 820-5213 Statement of Survey...1993 2336 W. Nopal Ave. Mesa, AZ 85202 (602) 820-5213 SUBJECT: Request for Assistance and Survey Sponsorship TO: HQ USAF/SCMV Lt Col Cultice 1. My

  11. Media Coverage of Toxic Risks: A Content Analysis of Pediatric Environmental Health Information Available to New and Expecting Mothers.

    Science.gov (United States)

    Mello, Susan

    2015-01-01

    Mass media play a central role in providing environmental health information to the public. Despite several decades of environmental and health communication research, the nature of environmental health information available to one of the most vulnerable populations--new and expecting mothers--has received limited attention. To address this gap, this study poses two questions: (1) How prevalent is information related to prenatal and pediatric environmental health (PPEH) in the media, and (2) how much coverage do the most concerning chemical threats to PPEH receive? A content analysis of 2,543 texts in popular media sources (i.e., the Associated Press [AP], parenting magazines, and parenting websites) from September 2012 to February 2013 revealed that roughly three pieces of PPEH information were made available to mothers daily. Prior research has shown that media coverage of environmental health issues has decreased over the years; however, these results suggest that at-risk populations are likely to encounter this type of information in the media. Also, while certain chemicals received ample coverage (i.e., pesticides, cigarette smoke, mercury), other issues deemed concerning by federal agencies did not (i.e., lead, phthalates). This study also introduces a novel method for harvesting online content encountered incidentally. Implications of these findings for communication research and practice are discussed.

  12. Department of the Air Force Information Technology Program FY 95 President’s Budget

    Science.gov (United States)

    1994-03-01

    Centers to provide connectivity between the various functional disibuted logstics management systems in the MSC a Program. This includes specialized...CMOS maintains inbound and outbound manifest registers, funding information, and workload data. CMOS provides an on-line history for shipment tracking

  13. Planning an Information System for a Small College. AIR Forum Paper 1978.

    Science.gov (United States)

    Toombs, William; Sagaria, Mary Ann

    Data collection and analyses of college records and interviewing provided a cross-sectional view of data flow and information transmission in a small college. The micro-analysis of interview data, forms, and reports yielded a picture of functional relationships, clarified loci of decision making, and stipulated functions served by data items.…

  14. Cartoneros, recolección informal, ambiente y políticas públicas en Buenos Aires 2001-2012 Scavengers, informal waste collection, public politics in Buenos Aires 2001-2012

    Directory of Open Access Journals (Sweden)

    Verónica Paiva

    2013-06-01

    Full Text Available El objetivo del artículo es analizar las características del circuito informal de recolección y recuperación residuos que se expandió desde fines de la década del ’90 y especialmente hacia el final del año 2001 en la ciudad de Buenos Aires, analizando las razones que provocaron la expansión de dicho circuito, las nuevas características que asume el cirujeo en dicha etapa y las posturas tomadas por la teoría ambiental y las políticas públicas frente a esta forma particular de recuperación de residuos que es prototípica de las ciudades latinoamericanas En forma paralela a la gestión oficial de los residuos se ha extendido una vía informal de recolección y recuperación que es llevado adelante por los sectores pobres de la sociedad que encuentran en la recolección y venta de residuos un camino para la supervivencia cotidiana. El artículo describe las características de dicho circuito informal, las rutas, calles, horarios y tipos de residuos recogidos y analiza el fenómeno no sólo como una expresión de la pobreza urbana sino como un modo de tratamiento de los desechos

  15. Community Multi-scale Air Quality (CMAQ) Modeling System for Air Quality Management

    Science.gov (United States)

    CMAQ simultaneously models multiple air pollutants including ozone, particulate matter and a variety of air toxics to help air quality managers determine the best air quality management scenarios for their communities, regions and states.

  16. Information draft on the development of air standards for methylisobutyl ketone

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-01-01

    Methylisobutyl ketone (MIBK) is a colourless, flammable substance with a fruity, ethereal odour. Its main use is as a solvent in protective coatings and chemical synthesis. It is also used as a process solvent to separate and purify various substances, including various chemicals, certain metal ions, antibiotics and other pharmaceuticals. In 1996 about 90 per cent of the total atmospheric releases in Canada occurred in Ontario. MIBK is primarily absorbed through the lungs. The respiratory and nervous systems, eyes and skin are most affected by exposure. Inhalation of MIBK may cause depression of the central nervous system, dizziness, nausea, confusion, or collapse, while skin contact may lead to dermatitis. The liver and kidneys may also be affected by chronic or repeated exposure to relatively high concentrations of MIBK. The current half-hour POI and the 24-hour AAQC standards are both set at 1,200 microgram/cubic meter, based on the odour effects of MIBK. The review of world-wide literature uncovered that several American states have promulgated air quality standards for MIBK based on the occupational exposure limit of 205,000 microgram/cubic meter, or 50 ppm, established by the National Institutes of Occupational Safety and Health (NIOSH), or the American Conference of Governmental Industrial Hygienists (ACGIH). 48 refs., 1 tab., appendix.

  17. Comparative Functional Analysis of Air Force and Commercially Available Transportation Information Management Systems

    Science.gov (United States)

    2004-03-01

    information management systems. Foster (2001) describes a gap analysis as “a term associated with the SERVQUAL survey instrument; gap analysis is a...Validity - Do pattern-matching - Do explanation-building - Address rival explanations - Use logic models Data analysis Data analysis Data...and redeployment modeling and simulation requirements. s. Joint Warfighting System (JWARS). JWARS is a closed-form, constructive simulation of

  18. Retrieving clear-air turbulence information from regular commercial aircraft using Mode-S and ADS-B broadcast

    Directory of Open Access Journals (Sweden)

    J. M. Kopeć

    2015-11-01

    Full Text Available Navigational information broadcast by commercial aircraft in the form of Mode-S and ADS-B messages can be considered a new and valid source of upper air turbulence measurements. A set of three processing methods is proposed and analysed using a quality record of turbulence encounters made by a research aircraft. The proposed methods are based on processing the vertical acceleration or the background wind into the eddy dissipation rate. All the necessary parameters are conveyed in the Mode-S/ADS-B messages. The comparison of the results of application of the processing against a reference eddy dissipation rate obtained using on-board accelerometer indicate a significant potential of those methods. The advantages and limitation of the presented approaches are discussed.

  19. Air pollution simulation and geographical information systems (GIS) applied to Athens International Airport.

    Science.gov (United States)

    Theophanides, Mike; Anastassopoulou, Jane

    2009-07-01

    This study presents an improved methodology for analysing atmospheric pollution around airports using Gaussian-plume numerical simulation integrated with Geographical Information Systems (GIS). The new methodology focuses on streamlining the lengthy analysis process for Airport Environmental Impact Assessments by integrating the definition of emission sources, simulating and displaying the results in a GIS environment. One of the objectives of the research is to validate the methodology applied to the Athens International Airport, "Eleftherios Venizelos", to produce a realistic estimate of emission inventories, dispersion simulations and comparison to measured data. The methodology used a combination of the Emission Dispersion and Modelling System (EDMS) and the Atmospheric Dispersion and Modelling system (ADMS) to improve the analysis process. The second objective is to conduct numerical simulations under various adverse conditions (e.g. scenarios) and assess the dispersion in the surrounding areas. The study concludes that the use of GIS in environmental assessments provides a valuable advantage for organizing data and entering accurate geographical/topological information for the simulation engine. Emissions simulation produced estimates within 10% of published values. Dispersion simulations indicate that airport pollution will affect neighbouring cities such as Rafina and Loutsa. Presently, there are no measured controls in these areas. In some cases, airport pollution can contribute to as much as 40% of permissible EU levels in VOCs.

  20. Hanford Waste Vitrification Plant technical background document for toxics best available control technology demonstration

    Energy Technology Data Exchange (ETDEWEB)

    None

    1992-10-01

    This document provides information on toxic air pollutant emissions to support the Notice of Construction for the proposed Hanford Waste Vitrification Plant (HWVP) to be built at the the Department of Energy Hanford Site near Richland, Washington. Because approval must be received prior to initiating construction of the facility, state and federal Clean Air Act Notices of construction are being prepared along with necessary support documentation.

  1. Toxic proteins in plants.

    Science.gov (United States)

    Dang, Liuyi; Van Damme, Els J M

    2015-09-01

    Plants have evolved to synthesize a variety of noxious compounds to cope with unfavorable circumstances, among which a large group of toxic proteins that play a critical role in plant defense against predators and microbes. Up to now, a wide range of harmful proteins have been discovered in different plants, including lectins, ribosome-inactivating proteins, protease inhibitors, ureases, arcelins, antimicrobial peptides and pore-forming toxins. To fulfill their role in plant defense, these proteins exhibit various degrees of toxicity towards animals, insects, bacteria or fungi. Numerous studies have been carried out to investigate the toxic effects and mode of action of these plant proteins in order to explore their possible applications. Indeed, because of their biological activities, toxic plant proteins are also considered as potentially useful tools in crop protection and in biomedical applications, such as cancer treatment. Genes encoding toxic plant proteins have been introduced into crop genomes using genetic engineering technology in order to increase the plant's resistance against pathogens and diseases. Despite the availability of ample information on toxic plant proteins, very few publications have attempted to summarize the research progress made during the last decades. This review focuses on the diversity of toxic plant proteins in view of their toxicity as well as their mode of action. Furthermore, an outlook towards the biological role(s) of these proteins and their potential applications is discussed.

  2. Air Sensor Toolbox

    Science.gov (United States)

    Air Sensor Toolbox provides information to citizen scientists, researchers and developers interested in learning more about new lower-cost compact air sensor technologies and tools for measuring air quality.

  3. AIRS Data Service at NASA Goddard Earth Sciences Data and Information Services (GES DISC) and Its Application to Climate Change Study

    Science.gov (United States)

    Won, Young-In; Vollimer, Bruce; Theobald, Mike; Hua, Xin-Min

    2008-01-01

    The Atmospheric Infrared Sounder (AIRS) instrument suite is designed to observe and characterize the entire atmospheric column from the surface to the top of the atmosphere in terms of surface emissivity and temperature, atmospheric temperature and humidity profiles, cloud amount and height, and the spectral outgoing infrared radiation on a global scale. The AIRS Data Support Team at the GES DISC provides data support to assist others in understanding, retrieving and extracting information from the AIRS/AMSU/HSB data products. Because a number of years has passed since its operation started, the amount of data has reached a certain level of maturity where we can address the climate change study utilizing AIRS data, In this presentation we will list various service we provide and to demonstrate how to utilize/apply the existing service to long-term and short-term variability study.

  4. Cooking practices, air quality, and the acceptability of advanced cookstoves in Haryana, India: an exploratory study to inform large-scale interventions

    Directory of Open Access Journals (Sweden)

    Rupak Mukhopadhyay

    2012-09-01

    Full Text Available Background: In India, approximately 66% of households rely on dung or woody biomass as fuels for cooking. These fuels are burned under inefficient conditions, leading to household air pollution (HAP and exposure to smoke containing toxic substances. Large-scale intervention efforts need to be informed by careful piloting to address multiple methodological and sociocultural issues. This exploratory study provides preliminary data for such an exercise from Palwal District, Haryana, India. Methods: Traditional cooking practices were assessed through semi-structured interviews in participating households. Philips and Oorja, two brands of commercially available advanced cookstoves with small blowers to improve combustion, were deployed in these households. Concentrations of particulate matter (PM with a diameter <2.5 μm (PM2.5 and carbon monoxide (CO related to traditional stove use were measured using real-time and integrated personal, microenvironmental samplers for optimizing protocols to evaluate exposure reduction. Qualitative data on acceptability of advanced stoves and objective measures of stove usage were also collected. Results: Twenty-eight of the thirty-two participating households had outdoor primary cooking spaces. Twenty households had liquefied petroleum gas (LPG but preferred traditional stoves as the cost of LPG was higher and because meals cooked on traditional stoves were perceived to taste better. Kitchen area concentrations and kitchen personal concentrations assessed during cooking events were very high, with respective mean PM2.5 concentrations of 468 and 718 µg/m3. Twenty-four hour outdoor concentrations averaged 400 µg/m3. Twenty-four hour personal CO concentrations ranged between 0.82 and 5.27 ppm. The Philips stove was used more often and for more hours than the Oorja. Conclusions: The high PM and CO concentrations reinforce the need for interventions that reduce HAP exposure in the aforementioned community. Of the two

  5. Toxic Elements

    DEFF Research Database (Denmark)

    Hajeb, Parvaneh; Shakibazadeh, Shahram; Sloth, Jens Jørgen

    2016-01-01

    Food is considered the main source of toxic element (arsenic, cadmium, lead, and mercury) exposure to humans, and they can cause major public health effects. In this chapter, we discuss the most important sources for toxic element in food and the foodstuffs which are significant contributors to h...

  6. Tungsten toxicity.

    Science.gov (United States)

    Witten, Mark L; Sheppard, Paul R; Witten, Brandon L

    2012-04-05

    There is emerging evidence that tungsten has toxic health effects. We summarize the recent tungsten toxicity research in this short review. Tungsten is widely used in many commercial and military applications because it has the second highest melting temperature of any element. Consequently, it is important to elucidate the potential health effects of tungsten.

  7. Statistical air quality mapping

    NARCIS (Netherlands)

    Kassteele, van de J.

    2006-01-01

    This thesis handles statistical mapping of air quality data. Policy makers require more and more detailed air quality information to take measures to improve air quality. Besides, researchers need detailed air quality information to assess health effects. Accurate and spatially highly resolved maps

  8. Air pollution from household solid fuel combustion in India: an overview of exposure and health related information to inform health research priorities

    OpenAIRE

    Balakrishnan, Kalpana; Ramaswamy, Padmavathi; Sambandam, Sankar; Thangavel, Gurusamy; Ghosh, Santu; Johnson, Priscilla; Mukhopadhyay, Krishnendu; Venugopal, Vidhya; Thanasekaraan, Vijayalakshmi

    2011-01-01

    Environmental and occupational risk factors contribute to nearly 40% of the national burden of disease in India, with air pollution in the indoor and outdoor environment ranking amongst leading risk factors. It is now recognized that the health burden from air pollution exposures that primarily occur in the rural indoors, from pollutants released during the incomplete combustion of solid fuels in households, may rival or even exceed the burden attributable to urban outdoor exposures. Few envi...

  9. Creating mechanisms of toxic substances emission of combustion engines

    Directory of Open Access Journals (Sweden)

    Jankowski Antoni

    2015-12-01

    Full Text Available The paper analyses the mechanisms of creation of toxic exhaust gases, which mainly derived from inexact fuel metering and improper air-fuel mixture preparation. The paper describes the process of creating toxic components in the exhaust gases of piston engines during engine operation, and impact on the emission of these components determining the composition of the fuel mixture determined equivalence factor Φ. The principal mechanisms of formation of toxic exhaust gases, in particular nitrogen oxides, carbon monoxide and hydrocarbons, and also essential according to create each of toxic exhaust gases are the subject of the paper. Moreover, empirical relationships, by means of which it is possible to determine the time of creation of the individual components of toxic exhaust gases, are presented. For example, one of the mechanisms for prompt formation of nitrogen oxides and hydrocarbons graphic illustration of formation as a function of crank angle is described. At the conclusion, the summary and significance of information on creation mechanisms of toxic components in the exhaust gases of piston engines are presented.

  10. Measurement of toxic volatile organic compounds in indoor air of semiconductor foundries using multisorbent adsorption/thermal desorption coupled with gas chromatography-mass spectrometry.

    Science.gov (United States)

    Wu, Chien-Hou; Lin, Ming-Nan; Feng, Chien-Tai; Yang, Kuang-Ling; Lo, Yu-Shiu; Lo, Jiunn-Guang

    2003-05-09

    A method for the qualitative and quantitative analysis of volatile organic compounds (VOCs) in the air of class-100 clean rooms at semiconductor fabrication facilities was developed. Air samples from two semiconductor factories were collected each hour on multisorbent tubes (including Carbopack B, Carbopack C, and Carbosieve SIII) with a 24-h automatic active sampling system and analyzed using adsorption/thermal desorption coupled with gas chromatography-mass spectrometry. Experimental parameters, including thermal desorption temperature, desorption time, and cryofocusing temperature, were optimized. The average recoveries and the method detection limits for the target compounds were in the range 94-101% and 0.31-0.89 ppb, respectively, under the conditions of a 1 L sampling volume and 80% relative humidity. VOCs such as acetone, isopropyl alcohol, 2-heptanone, and toluene, which are commonly used in the semiconductor and electronics industries, were detected and accurately quantified with the established method. Temporal variations of the analyte concentrations observed were attributed to the improper use of organic solvents during operation.

  11. Final Regulations to Reduce Toxic Air Pollutant Emissions from Brick and Structural Clay Products Manufacturing and Clay Ceramics Manufacturing Fact Sheets

    Science.gov (United States)

    This page contains a February 2003 and September 2015 fact sheet with information regarding the final rules to the NESHAP for Brick and Structural Clay Products Manufacturing and the NESHAP for Clay Ceramics Manufacturing

  12. Toxic Release Inventory Chemicals by Groupings

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Toxics Release Inventory (TRI) makes available information for more than 600 toxic chemicals that are being used, manufactured, treated, transported, or released...

  13. Reported toxicity in 1486 liquid detergent capsule exposures to the UK National Poisons Information Service 2009-2012, including their ophthalmic and CNS effects.

    Science.gov (United States)

    Williams, Hayley; Jones, Stephen; Wood, Kelly; Scott, Robert A H; Eddleston, Michael; Thomas, Simon H L; Thompson, John Paul; Vale, J Allister

    2014-02-01

    CONTEXT. Data on the ophthalmic and central nervous system (CNS) adverse effects of liquid detergent capsules (liquid laundry pods) are limited. OBJECTIVE. To ascertain the reported toxicity of liquid detergent capsules, particularly their ophthalmic and CNS adverse effects, in a large case series. METHODS. Between 1 May 2009 and 30 July 2012 the UK National Poisons Information Service collected prospectively 1509 telephone enquiries (involving 1486 exposures) relating to liquid detergent capsules. RESULTS. The majority of patients (95.6%) were children aged less than 5. Exposure to these products occurred mainly as a result of ingestion alone (n = 1215; 81.8%), with eye contact alone (n = 110; 7.4%), and skin contact alone (n = 20; 1.3%) being less common; multiple routes of exposure were involved in 141 (9.5%) cases. Following ocular exposure (n = 212), features suggesting conjunctivitis (n = 145; 68.4%) and corneal ulceration (n = 6; 2.8%) developed. The most common features reported following ingestion alone were nausea and vomiting (n = 721; 59.3%), followed by coughing (n = 53; 4.4%), drowsiness/CNS depression (n = 49; 42 of these were children were aged 2 years or less) and foaming at the mouth (n = 47; 3.9%). A rash occurred in 22 patients where ingestion was considered to be the route of exposure. Twenty patients were exposed via the dermal route alone and developed erythema (n = 9), rash (n = 6) and burn (n = 3). CONCLUSIONS. Ocular exposure to liquid detergent capsules may lead to conjunctivitis and corneal ulceration; detergent ingestion may result in central nervous system (CNS)depression. Greater consumer awareness is required to reduce injury from liquid detergent capsules, particularly that involving the eye.

  14. [Toxicity of puffer fish fins].

    Science.gov (United States)

    Honda, Shunichi; Ichimaru, Shunichi; Arakawa, Osamu; Takatani, Tomohiro; Noguchi, Tamao; Ishizaki, Shoichiro; Nagashima, Yuji

    2007-10-01

    Puffer fish is prized as a Japanese traditional food and its fin is also used in the cuisine. However, whether the fin is edible or not is determined for convenience from the toxicity of skin, since little information is available about the toxicity of puffer fish fins. In the present study, we examined the toxicity of fins and skin of three toxic species, Takifugu vermicularis, T. snyderi, and T. porphyreus. The toxicity of T. vermicularis fins (< 5-52.4 MU/g) was significantly lower than that of skin (<5-1200 MU/g). HPLC analysis showed that tetrodotoxin was a major toxic principle irrespective of the toxicity value in each tissue of T. vermicularis. In the case of T. snyderi and T. porphyreus, the toxicity of fins was at almost the same level as that of the skin. The toxicity (< 10-12 MU/g) of caudal fins of T. porphyreus was apparently increased to 16.5-22.0 MU/g by drying. However, the toxin amounts in the dried fins were slightly decreased as compared with those of the non-dried fins. These results demonstrate that puffer fish with toxic skin also have toxic fins.

  15. Human Toxicity

    DEFF Research Database (Denmark)

    Jolliet, Olivier; Fantke, Peter

    2015-01-01

    . The first section of this chapter outlines the complete cause-effect pathway, from emissions of toxic substances to intake by the population up to damages in terms of human health effects. Section 2 outlines the framework for assessing human toxicity in LCIA. Section 3 discusses the contributing substances......This chapter reviews the human toxicological impacts of chemicals and how to assess these impacts in life cycle impact assessment (LCIA), in order to identify key processes and pollutants. The complete cause-effect pathway – from emissions of toxic substances up to damages on human health...... – demonstrates the importance to account for both outdoor and indoor exposure, including consumer products. Analysing the variations in intake fraction (the fraction of the emitted or applied chemical that is taken in by the consumer and the general population), effect factor and characterisation factor across...

  16. Geochemical anomalies of toxic elements and arsenic speciation in airborne particles from Cu mining and smelting activities: influence on air quality.

    Science.gov (United States)

    Sánchez de la Campa, Ana M; Sánchez-Rodas, Daniel; González Castanedo, Yolanda; de la Rosa, Jesús D

    2015-06-30

    A characterization of chemical composition and source contribution of PM10 in three representative environments of southwest Spain related to mining activities (mineral extraction, mining waste and Cu-smelting) has been performed. A study of geochemical anomalies was conducted in the samples collected at the three stations between July 2012 and October 2013. The influence of Cu-smelting processes was compared to other mining activities, where common tracers were identified. The Cu and As concentrations in the study area are higher than in other rural and urban stations of Spain, in which geochemical anomalies of As, Se, Bi, Cd, and Pb have been reported. The results of source contribution showed similar geochemical signatures in the industrial and mining factors. However, the contribution to PM10 is different according to the type of industrial activity. These results have been confirmed performing an arsenic speciation analysis of the PM10 samples, in which the mean extraction efficiency of arsenic depended on the origin of the samples. These finding indicate that the atmospheric particulate matter emitted from Cu-smelting has a high residence time in the atmosphere. This indicates that the Cu-smelter can impact areas of high ecological interest and considered as clean air.

  17. Toxic myopathies.

    Science.gov (United States)

    Pasnoor, Mamatha; Barohn, Richard J; Dimachkie, Mazen M

    2014-08-01

    Muscle tissue is highly sensitive to many substances. Early recognition of toxic myopathies is important, because they potentially are reversible on removal of the offending drug or toxin, with greater likelihood of complete resolution the sooner this is achieved. Clinical features range from mild muscle pain and cramps to severe weakness with rhabdomyolysis, renal failure, and even death. The pathogenic bases can be multifactorial. This article reviews some of the common toxic myopathies and their clinical presentation, histopathologic features, and possible underlying cellular mechanisms.

  18. Neurological oxygen toxicity.

    Science.gov (United States)

    Farmery, Scott; Sykes, Oliver

    2012-10-01

    SCUBA diving has several risks associated with it from breathing air under pressure--nitrogen narcosis, barotrauma and decompression sickness (the bends). Trimix SCUBA diving involves regulating mixtures of nitrogen, oxygen and helium in an attempt to overcome the risks of narcosis and decompression sickness during deep dives, but introduces other potential hazards such as hypoxia and oxygen toxicity convulsions. This study reports on a seizure during the ascent phase, its potential causes and management and discusses the hazards posed to the diver and his rescuer by an emergency ascent to the surface.

  19. A review of toxicity studies on graphene-based nanomaterials in laboratory animals.

    Science.gov (United States)

    Ema, Makoto; Gamo, Masashi; Honda, Kazumasa

    2017-04-01

    We summarized the findings of toxicity studies on graphene-based nanomaterials (GNMs) in laboratory mammals. The inhalation of graphene (GP) and graphene oxide (GO) induced only minimal pulmonary toxicity. Bolus airway exposure to GP and GO caused acute and subacute pulmonary inflammation. Large-sized GO (L-GO) was more toxic than small-sized GO (S-GO). Intratracheally administered GP passed through the air-blood barrier into the blood and intravenous GO distributed mainly in the lungs, liver, and spleen. S-GO and L-GO mainly accumulated in the liver and lungs, respectively. Limited information showed the potential behavioral, reproductive, and developmental toxicity and genotoxicity of GNMs. There are indications that oxidative stress and inflammation may be involved in the toxicity of GNMs. The surface reactivity, size, and dispersion status of GNMs play an important role in the induction of toxicity and biodistribution of GNMs. Although this review paper provides initial information on the potential toxicity of GNMs, data are still very limited, especially when taking into account the many different types of GNMs and their potential modifications. To fill the data gap, further studies should be performed using laboratory mammals exposed using the route and dose anticipated for human exposure scenarios.

  20. Toxic Picoplanktonic Cyanobacteria—Review

    Directory of Open Access Journals (Sweden)

    Natalia Jakubowska

    2015-03-01

    Full Text Available Cyanobacteria of a picoplanktonic cell size (0.2 to 2.0 µm are common organisms of both freshwater and marine ecosystems. However, due to their small size and relatively short study history, picoplanktonic cyanobacteria, in contrast to the microplanktonic cyanobacteria, still remains a poorly studied fraction of plankton. So far, only little information on picocyanobacteria toxicity has been reported, while the number of reports concerning their presence in ecosystems is increasing. Thus, the issue of picocyanobacteria toxicity needs more researchers’ attention and interest. In this report, we present information on the current knowledge concerning the picocyanobacteria toxicity, as well as their harmfulness and problems they can cause.

  1. Toxic picoplanktonic cyanobacteria--review.

    Science.gov (United States)

    Jakubowska, Natalia; Szeląg-Wasielewska, Elżbieta

    2015-03-18

    Cyanobacteria of a picoplanktonic cell size (0.2 to 2.0 µm) are common organisms of both freshwater and marine ecosystems. However, due to their small size and relatively short study history, picoplanktonic cyanobacteria, in contrast to the microplanktonic cyanobacteria, still remains a poorly studied fraction of plankton. So far, only little information on picocyanobacteria toxicity has been reported, while the number of reports concerning their presence in ecosystems is increasing. Thus, the issue of picocyanobacteria toxicity needs more researchers' attention and interest. In this report, we present information on the current knowledge concerning the picocyanobacteria toxicity, as well as their harmfulness and problems they can cause.

  2. Nanostructured Catalytic Reactors for Air Purification Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This SBIR Phase I project proposes the development of lightweight compact nanostructured catalytic reactors for air purification from toxic gaseous organic...

  3. Nanostructured Catalytic Reactors for Air Purification Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This SBIR Phase II project proposes the development of lightweight compact nanostructured catalytic reactors for air purification from toxic gaseous organic...

  4. The APHEIS project. An information source on air pollution and health impacts in Europe; Das Projekt APHEIS. Eine Informationsquelle fuer Luftverschmutzung und Gesundheit in Europa

    Energy Technology Data Exchange (ETDEWEB)

    Medina, S. [Institut de Veille Sanitaire, Saint Maurice (France); Plasencia, A. [Institut Municipal de Salut Publica de Barcelona (Spain); Muecke, H.G. [Umweltbundesamt, Berlin (Germany). WHO Collaborating Centre for Air Quality Management and Air Pollution Control

    2001-05-01

    The objectives of the APHEIS project are to: - establish a European epidemiological monitoring system, as well as a special database providing information on air pollution and its impacts on public health, - quantify the time-related effects of air pollution on public health at the local, national and European level, - examine and reveal the impacts of different factors on the cause-and-effect patterns, - publish at regular intervals standardised reports on the impact of air pollution on public health, so as to provide the participating three user groups of APHEIS with the information they need. (orig./CB) [German] Das APHEIS-Projekt soll - ein europaeisches epidemiologisches Ueberwachungssystem schaffen, das eine umfassende Datenbank zum Thema Luftverschmutzung und oeffentliche Gesundheit beinhalten wird, - die Wirkungen von Luftverschmutzung auf die oeffentliche Gesundheit auf der lokalen, nationalen und europaeischen Ebene zeitlich quantifizieren, - den Einfluss von Faktoren auf Expositions- und Wirkungszusammenhaenge bewerten, - regelmaessig standardisierte Berichte ueber den Einfluss von Luftverschmutzung auf die oeffentliche Gesudheit liefern, die den Informationsbeduerfnissen der drei Benutzergruppen von APHEIS entsprechen. (orig.)

  5. Air Pollution Monitoring | Air Quality Planning & Standards ...

    Science.gov (United States)

    2016-06-08

    The basic mission of the Office of Air Quality Planning and Standards is to preserve and improve the quality of our nation's air. To accomplish this, OAQPS must be able to evaluate the status of the atmosphere as compared to clean air standards and historical information.

  6. Patent Information Analysis on Air Purification%空气净化技术专利情报分析

    Institute of Scientific and Technical Information of China (English)

    田军; 王晓鹏

    2014-01-01

    In this article, the basic trend of patent about air purification was analysed by year amount of patent application, areal distribu-tion and patent assignee using Thomoson Innovation. The analysis showed that application quantity of patent about air purification in-creased rapidly from 1999, and the main applicant countries were America, Japan and China. The primary patent assignees were Panason-ic, LG electronics and Donaldson. Technical constitution of air purification was analysed through International Patent Classification (IPC). The research found that major technologies in air purification were the filter and electrostatic separation of particulate matter, disin-fection and sterilization of air, and air-conditioning system. The key technology of main patent assignee was also analysed by patent the-mescape. Panasonic and LG focused on indoor air purification, but Donaldson involved industry air purification. The patent themescape al-so showed that patent layout of many research institutions and companies had related to almost all of the technology of air purification, but Chinese research institutions and companies had little patents.%利用专利情报分析工具Thomoson Innovation,分别通过每年专利申请量、区域分布、专利权人分析了空气净化领域的国际专利基本态势。通过分析得知,空气净化领域的专利申请量从1999年开始出现了迅速的增加,主要分布于美国、日本和中国,主要的专利权人为日本松下(Panasonic)、韩国乐金(LG)、美国唐纳森(Donaldson)公司。通过IPC分类分析了空气净化领域的技术构成,研究发现,空气净化涉及的主要技术领域包括颗粒物的过滤和静电分离、空气的消毒杀菌和空气的调节系统等。同时通过专利主题地形图分析了主要专利权人的技术特点,日本松下和韩国乐金主要集中于室内空气的净化,而美国唐纳森(Donaldson)的技术布局主要涉及工业空气净化。通过专

  7. Contamination of indoor dust and air by polychlorinated biphenyls and brominated flame retardants and relevance of non-dietary exposure in Vietnamese informal e-waste recycling sites.

    Science.gov (United States)

    Tue, Nguyen Minh; Takahashi, Shin; Suzuki, Go; Isobe, Tomohiko; Viet, Pham Hung; Kobara, Yuso; Seike, Nobuyasu; Zhang, Gan; Sudaryanto, Agus; Tanabe, Shinsuke

    2013-01-01

    This study investigated the occurrence of polychlorinated biphenyls (PCBs), and several additive brominated flame retardants (BFRs) in indoor dust and air from two Vietnamese informal e-waste recycling sites (EWRSs) and an urban site in order to assess the relevance of these media for human exposure. The levels of polybrominated diphenyl ethers (PBDEs), hexabromocyclododecane (HBCD), 1,2-bis-(2,4,6-tribromophenoxy)ethane (BTBPE) and decabromodiphenyl ethane (DBDPE) in settled house dust from the EWRSs (130-12,000, 5.4-400, 5.2-620 and 31-1400 ng g(-1), respectively) were significantly higher than in urban house dust but the levels of PCBs (4.8-320 ng g(-1)) were not higher. The levels of PCBs and PBDEs in air at e-waste recycling houses (1000-1800 and 620-720 pg m(-3), respectively), determined using passive sampling, were also higher compared with non-e-waste houses. The composition of BFRs in EWRS samples suggests the influence from high-temperature processes and occurrence of waste materials containing older BFR formulations. Results of daily intake estimation for e-waste recycling workers are in good agreement with the accumulation patterns previously observed in human milk and indicate that dust ingestion contributes a large portion of the PBDE intake (60%-88%), and air inhalation to the low-chlorinated PCB intake (>80% for triCBs) due to their high levels in dust and air, respectively. Further investigation of both indoor dust and air as the exposure media for other e-waste recycling-related contaminants and assessment of health risk associated with exposure to these contaminant mixtures is necessary.

  8. AirCompare

    Data.gov (United States)

    U.S. Environmental Protection Agency — AirCompare contains air quality information that allows a user to compare conditions in different localities over time and compare conditions in the same location...

  9. Epidermal characteristics of toxic plants for cattle from the Salado River basin (Buenos Aires, Argentina Caracteres epidérmicos de las plantas tóxicas para el ganado de la Depresión del Salado (Buenos Aires, Argentina

    Directory of Open Access Journals (Sweden)

    Susana E. Freire

    2005-12-01

    Full Text Available One hundred and eighty species belonging to 41 families inhabiting the Salado River Basin of the province of Buenos Aires (Argentina were previously reported to be toxic for cattle. The purpose of this study was to provide a tool to distinguish the taxa when the plant material is desintegrated. In this way, an approach to the identification of these taxa through leaf epidermal features (anticlinal epidermal cell wall patterns, cuticular ornamentation, stomata, and hair types is performed. A key to the 180 species as well as illustrations of diagnostic characters are given.Las plantas tóxicas para el ganado están representadas en la Depresión del Salado (provincia de Buenos Aires, Argentina por 180 especies pertenecientes a 41 familias. El objetivo del presente trabajo es determinar estos taxa a partir de material desintegrado, utilizando caracteres epidérmicos foliares (paredes anticlinales de las células epidérmicas, ornamentación de la cutícula, tipos de estomas y pelos. Se brinda una clave para la determinación de las especies e ilustraciones de los caracteres diagnósticos.

  10. Toxic Substances Control Act

    Energy Technology Data Exchange (ETDEWEB)

    1992-05-15

    This Reference Book contains a current copy of the Toxic Substances Control Act and those regulations that implement the statute and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (202/586-2609).

  11. The role of threshold limit values in U. S. air pollution policy

    Energy Technology Data Exchange (ETDEWEB)

    Robinson, J.C.; Paxman, D.G. (Center for Occupational and Environmental Health, School of Public Health, University of California, Berkeley (United States))

    1992-01-01

    This paper analyzes the role of threshold limit values (TLVs) in national air pollution policy during the 1980s, a period in which the Environmental Protection Agency (EPA) sought to delegate to individual states the authority to evaluate and regulate airborne toxic substances. We focus on 20 carcinogens and 11 substances with non-genotoxic health effects that were regulated by local air toxics programs using TLVs. Data from EPA's National Air Toxics Information Clearinghouse indicate that maximum TLV-based Ambient Air Level guidelines (AALs) frequently exceed minimum TLV-based AALs by a factor of greater than 1,000. Cancer potency data from EPA's Integrated Risk Information System suggest significant risks remain at TLV-based AALs. Cancer risks at the median TLV-based AAL exceed 1,000 cases per million exposed persons for cadmium (1,040), nickel and its compounds (1,420), propylene oxide (1,550), coke oven emissions (1,860), benzene (2,500), arsenic and its compounds (7,300), N-nitrosodimethylamine (21,000), asbestos (21,500), and ethylene dibromide (55,000). We also summarize published studies that report non-genotoxic health effects in workers exposed at levels near the TLV for 11 substances whose AALs were based on TLVs. Contrary to the assumption frequently made by state air toxics program, TLVs cannot be taken to represent no observed effect levels (NOELs) for regulatory purposes.

  12. Technical conference on air, noise, and waste - current information for multipliers in industry. Current information for multipliers in industry; Fachtagung Luft, Laerm, Abfall - Aktuelle Informationen fuer Multiplikatoren der Wirtschaft. Aktuelle Informationen fuer Multiplikatoren der Wirtschaft

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    The Bavarian Environmental Office informed on the new information and documentation centre for environmental technology and environmental management (IDZ), new amendments to air pollution abatement legislation and their implementation, experience from the practical application of the amended TA Laerm (Noise Regulation), the Ordinance on Noise Emitted by Equipment and Machines, and methods of supervising the disposal of classified waste according to the Ordinance on Waste from Small Industries (Gewerbeabfallverordnung). [German] DAs bayerische Landesamt fuer Umweltschutz informierte in der Tagung ueber: IDZ - Informations und Dokumentationszentrum fuer Umwelttechnologie und umweltmanagement, aktuelle Aenderungen der Gesetzgebung zur Luftreinhaltung und ihre Anwendung, Erfahrungen aus dem Vollzug der Aenderung der TA Laerm, Geraete und Maschinenlaermschutzverordnung und Nachweisverfahren ueber die Entsorgung ueberwachungsbeduerftiger Abfaelle in der Gewerbeabfallverordung. (uke)

  13. Informe sobre el conjunto de grabados rupestres al aire libre de la «Braña de los Pastores», Cabrojo (Santander

    Directory of Open Access Journals (Sweden)

    Rodrigo de BALBÍN BEHRMANN

    2009-10-01

    Full Text Available El conjunto de grabados rupestres al aire libre a que hace referencia este informe, es conocido en la bibliografía desde los años veinte, merced a las publicaciones de su descubridor, J. Carballo 1. Falto de un estudio de detalle y prácticamente perdida su ubicación, ha sido objeto de la atención de este Departamento, ante el interés de estas manifestaciones en relación con los nuevos hallazgos arqueológicos de la región.

  14. Computing and Interpreting Fisher Information as a Metric of Sustainability: Regime Changes in the United States Air Quality

    Science.gov (United States)

    As a key tool in information theory, Fisher Information has been used to explore the observable behavior of a variety of systems. In particular, recent work has demonstrated its ability to assess the dynamic order of real and model systems. However, in order to solidify the use o...

  15. Hanford Site Air Operating Permit Application Supplemental Information [Sec 1 Thru 5] Vol 1 Thru 3 Appendices A Thru C

    Energy Technology Data Exchange (ETDEWEB)

    CURN, B.L.

    2000-05-01

    This report documents radionuclide air emissions from the Hanford Site in 1998 and the resulting effective dose equivalent to the maximally exposed individual (MEI) member of the public. The report has been prepared in accordance with the Code of Federal Regulations, Title 40, Protection of the Environment, Part 61, National Emission Standards for Hazardous Air Pollutants (40 CFR 61), Subpart H: ''National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities,'' and with the Washington Administrative Code Chapter 246247, Radiation Protection - Air Emissions. The federal regulations in 40 CFR 61, Subpart H, require the measurement and reporting of radionuclides emitted from Department of Energy facilities and the resulting offsite dose from those emissions. A standard of 10 mrem/yr effective dose equivalent (EDE) is imposed on them. The EDE to the MEI due to routine emissions in 1998 from Hanford Site point sources was 1.3 E-02 mrem (1.3 E-04 mSv). which is 0.13 percent of the federal standard. Chapter 246-247 of the Washington Administrative Code (WAC) requires the reporting of radionuclide emissions from all Department of Energy Hanford Site sources. The state has adopted into these regulations the 40 CFR 61 standard of 10 mrem/yr EDE. The EDE to the MEI attributable to diffuse and fugitive radionuclide air emissions from the Hanford Site in 1998 was 2.5 E-02 mrem (2.S E-04 mSv). This dose added to the dose from point sources gives a total for all sources of 3.8 E-02 mrem/yr (3.8 E-04 mSv) EDE. which is 0.38 percent of the 10 mrem/yr standard. An unplanned release on August 26, 1998, in the 300 Area of the Hanford Site resulted in a potential dose of 4.1 E-02 mrem to a hypothetical individual at the nearest point of public access to that area. This hypothetical individual was not the MEI since the wind direction on the day of the release was away from the MEI residence. The potential dose from

  16. Information Regarding Implementation of the Emission Trading Program Pursuant to 45 CSR28, Air Pollutant Emissions Banking and Trading

    Science.gov (United States)

    This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Policy and Guidance Database available at www2.epa.gov/title-v-operating-permits/title-v-operating-permit-policy-and-guidance-document-index. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  17. Multisensor system for toxic gases detection generated on indoor environments

    Science.gov (United States)

    Durán, C. M.; Monsalve, P. A. G.; Mosquera, C. J.

    2016-11-01

    This work describes a wireless multisensory system for different toxic gases detection generated on indoor environments (i.e., Underground coal mines, etc.). The artificial multisensory system proposed in this study was developed through a set of six chemical gas sensors (MQ) of low cost with overlapping sensitivities to detect hazardous gases in the air. A statistical parameter was implemented to the data set and two pattern recognition methods such as Principal Component Analysis (PCA) and Discriminant Function Analysis (DFA) were used for feature selection. The toxic gases categories were classified with a Probabilistic Neural Network (PNN) in order to validate the results previously obtained. The tests were carried out to verify feasibility of the application through a wireless communication model which allowed to monitor and store the information of the sensor signals for the appropriate analysis. The success rate in the measures discrimination was 100%, using an artificial neural network where leave-one-out was used as cross validation method.

  18. Information

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    There are unstructured abstracts (no more than 256 words) and structured abstracts (no more than 480). The specific requirements for structured abstracts are as follows:An informative, structured abstracts of no more than 4-80 words should accompany each manuscript. Abstracts for original contributions should be structured into the following sections. AIM (no more than 20 words): Only the purpose should be included. Please write the aim as the form of "To investigate/ study/..."; MATERIALS AND METHODS (no more than 140 words); RESULTS (no more than 294 words): You should present P values where appropnate and must provide relevant data to illustrate how they were obtained, e.g. 6.92 ± 3.86 vs 3.61 ± 1.67, P< 0.001; CONCLUSION (no more than 26 words).

  19. Indoor Air Pollution (Environmental Health Student Portal)

    Science.gov (United States)

    Skip Navigation National Library of Medicine Environmental Health Student Portal Connecting Middle School Students to Environmental Health Information Menu Home Air Pollution Air Pollution Home Indoor Air Pollution Outdoor Air ...

  20. Air Sensor Toolbox: Resources and Funding

    Science.gov (United States)

    EPA’s Air Sensor Toolbox provides information and guidance on new low-cost compact technologies for measuring air quality. It provides information to help citizens more effectively and accurately collect air quality data in their community.

  1. The new Internet tool: the information and evaluation system by flight, of exposure to cosmic radiation in the new air transports S.I.E.V.E.R.T; Un nouvel outil internet: le systeme d'information et d'evaluation par vol, de l'exposition au rayonnement cosmique dans les transports aeriens SIEVERT

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-03-01

    In France, the public authorities put a new Internet tool at air companies disposal, in order they can evaluate the radiations doses received by their flying crews during their flights. This tool called information and evaluation system by flight of exposure to cosmic radiation in air transport (S.I.E.V.E.R.T.). (N.C.)

  2. A study of toxic emissions from a coal-fired gasification plant. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-01

    Under the Fine Particulate Control/Air Toxics Program, the US Department of Energy (DOE) has been performing comprehensive assessments of toxic substance emissions from coal-fired electric utility units. An objective of this program is to provide information to the US Environmental Protection Agency (EPA) for use in evaluating hazardous air pollutant emissions as required by the Clean Air Act Amendments (CAAA) of 1990. The Electric Power Research Institute (EPRI) has also performed comprehensive assessments of emissions from many power plants and provided the information to the EPA. The DOE program was implemented in two. Phase 1 involved the characterization of eight utility units, with options to sample additional units in Phase 2. Radian was one of five contractors selected to perform these toxic emission assessments.Radian`s Phase 1 test site was at southern Company Service`s Plant Yates, Unit 1, which, as part of the DOE`s Clean Coal Technology Program, was demonstrating the CT-121 flue gas desulfurization technology. A commercial-scale prototype integrated gasification-combined cycle (IGCC) power plant was selected by DOE for Phase 2 testing. Funding for the Phase 2 effort was provided by DOE, with assistance from EPRI and the host site, the Louisiana Gasification Technology, Inc. (LGTI) project This document presents the results of that effort.

  3. Air Quality Monitoring Programme

    DEFF Research Database (Denmark)

    Kemp, K.; Palmgren, F.

    The air quality in Danish cities has been monitored continuously since 1982 within the Danish Air Quality (LMP) network. The aim has been to follow the concentration levels of toxic pollutants in the urban atmosphere and to provide the necessary knowledge to assess the trends, to perform source...... apportionment, and to evaluate the chemical reactions and the dispersion of the pollutants in the atmosphere. In 2002 the air quality was measured in four Danish cities and at two background sites. NO2 and PM10 were at several stations found in concentrations above the new EU limit values, which the Member...

  4. Urbanizaciones de origen informal en Buenos Aires. Lógicas de producción de suelo urbano y acceso a la vivienda

    Directory of Open Access Journals (Sweden)

    María Mercedes Di Virgilio

    2015-01-01

    Full Text Available El Área Metropolitana de Buenos Aires (AMBA convive desde sus orígenes con múltiples modalidades de informalidad urbana. Este trabajo analiza el proceso de producción y transformación de las formas de hábitat informal que se desarrollan sobre tierra vacante en el AMBA. Los resultados que se presentan forman parte de una investigación que indaga sobre las transformaciones de cuatro urbanizaciones populares del AMBA desde su origen hasta la actualidad, por medio de técnicas cuantitativas y cualitativas. El artículo dialoga con investigaciones que estudian la vida cotidiana de los sectores populares y sus formas de acceso al hábitat en las últimas décadas.

  5. Development of standardized air-blown coal gasifier/gas turbine concepts for future electric power systems. Volume 5, Appendix D: Cost support information: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Sadowski, R.S.; Brown, M.J.; Harriz, J.T.; Ostrowski, E.

    1991-01-01

    The cost estimate provided for the DOE sponsored study of Air Blown Coal Gasification was developed from vendor quotes obtained directly for the equipment needed in the 50 MW, 100 MW, and 200 MW sized plants and from quotes from other jobs that have been referenced to apply to the particular cycle. Quotes were generally obtained for the 100 MW cycle and a scale up/down factor was used to generate the cost estimates for the 200 MW and 50 MW cycles, respectively. Information from GTPro (property of Thermoflow, Inc.) was used to estimate the cost of the 200 MW and 50 MW gas turbine, HRSG, and steam turbines. To available the use of GTPro`s estimated values for this equipment, a comparison was made between the quotes obtained for the 100 MW cycle (ABB GT 11N combustion turbine and a HSRG) against the estimated values by GTPro.

  6. Olfactory toxicity in fishes.

    Science.gov (United States)

    Tierney, Keith B; Baldwin, David H; Hara, Toshiaki J; Ross, Peter S; Scholz, Nathaniel L; Kennedy, Christopher J

    2010-01-21

    Olfaction conveys critical environmental information to fishes, enabling activities such as mating, locating food, discriminating kin, avoiding predators and homing. All of these behaviors can be impaired or lost as a result of exposure to toxic contaminants in surface waters. Historically, teleost olfaction studies have focused on behavioral responses to anthropogenic contaminants (e.g., avoidance). More recently, there has been a shift towards understanding the underlying mechanisms and functional significance of contaminant-mediated changes in fish olfaction. This includes a consideration of how contaminants affect the olfactory nervous system and, by extension, the downstream physiological and behavioral processes that together comprise a normal response to naturally occurring stimuli (e.g., reproductive priming or releasing pheromones). Numerous studies spanning several species have shown that ecologically relevant exposures to common pollutants such as metals and pesticides can interfere with fish olfaction and disrupt life history processes that determine individual survival and reproductive success. This represents one of the pathways by which toxic chemicals in aquatic habitats may increasingly contribute to the decline and at-risk status of many commercially and ecologically important fish stocks. Despite our emerging understanding of the threats that pollution poses for chemical communication in aquatic communities, many research challenges remain. These include: (1) the determination of specific mechanisms of toxicity in the fish olfactory sensory epithelium; (2) an understanding of the impacts of complex chemical mixtures; (3) the capacity to assess olfactory toxicity in fish in situ; (4) the impacts of toxins on olfactory-mediated behaviors that are still poorly understood for many fish species; and (5) the connections between sublethal effects on individual fish and the long-term viability of wild populations. This review summarizes and integrates

  7. The TOMPs ambient air monitoring network - Continuous data on UK air quality for over 20 years.

    Science.gov (United States)

    Graf, Carola; Katsoyiannis, Athanasios; Jones, Kevin C; Sweetman, Andrew J

    2016-10-01

    Long-term air monitoring datasets are needed for persistent organic pollutants (POPs) to assess the effectiveness of source abatement measures and the factors controlling ambient levels. The Toxic Organic Micro Pollutants (TOMPs) Network, which has operated since 1991, collects ambient air samples at six sites across England and Scotland, using high-volume active air samplers. The network provides long-term ambient air trend data for a range of POPs at both urban and rural locations. Data from the network provides the UK Government, regulators and researchers with valuable information on emission/source controls and on the effectiveness of international chemicals regulation such as the Stockholm Convention and UN/ECE Protocol on POPs. The target chemicals of TOMPs have been polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and, since 2010, polybrominated diphenyl ethers (PBDEs). The continuous monitoring of these compounds demonstrates the constant decline in UK air concentrations over the last two decades, with average clearance rates for PCDD/Fs in urban locations of 5.1 years and for PCBs across all sites 6.6 years. No significant declines in rural locations for PCDD/Fs have been observed. There is a strong observable link between the declining ambient air concentrations and the emission reductions estimated in the annually produced National Atmospheric Emission Inventory (NAEI) dataset. These findings clearly demonstrate the unique strengths of long-term consistent datasets for the evaluation of the success of chemical regulation and control.

  8. Distributed Structure Searchable Toxicity

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Distributed Structure Searchable Toxicity (DSSTox) online resource provides high quality chemical structures and annotations in association with toxicity data....

  9. Toxic Substances: Information on Costs and Financial Aid to Schools To Control Asbestos. Fact Sheet for the Honorable John J. La Falce, House of Representatives.

    Science.gov (United States)

    General Accounting Office, Washington, DC. Resources, Community, and Economic Development Div.

    Information on the costs of and financial aid available to schools for asbestos abatement is provided in this report. Data are based on interviews with officials from 15 school districts in 5 states--Illinois, New Jersey, New York, Ohio, and Pennsylvania. Section 1 provides background on the use of asbestos in buildings, health problems, federal…

  10. Assessment and prediction of air quality using fuzzy logic and autoregressive models

    Science.gov (United States)

    Carbajal-Hernández, José Juan; Sánchez-Fernández, Luis P.; Carrasco-Ochoa, Jesús A.; Martínez-Trinidad, José Fco.

    2012-12-01

    In recent years, artificial intelligence methods have been used for the treatment of environmental problems. This work, presents two models for assessment and prediction of air quality. First, we develop a new computational model for air quality assessment in order to evaluate toxic compounds that can harm sensitive people in urban areas, affecting their normal activities. In this model we propose to use a Sigma operator to statistically asses air quality parameters using their historical data information and determining their negative impact in air quality based on toxicity limits, frequency average and deviations of toxicological tests. We also introduce a fuzzy inference system to perform parameter classification using a reasoning process and integrating them in an air quality index describing the pollution levels in five stages: excellent, good, regular, bad and danger, respectively. The second model proposed in this work predicts air quality concentrations using an autoregressive model, providing a predicted air quality index based on the fuzzy inference system previously developed. Using data from Mexico City Atmospheric Monitoring System, we perform a comparison among air quality indices developed for environmental agencies and similar models. Our results show that our models are an appropriate tool for assessing site pollution and for providing guidance to improve contingency actions in urban areas.

  11. A.P.H.E.I.S.:air Pollution and Health: A European Information System Health Impact Assessment of Air Pollution In 26 European Cities; Synthese des resultats europeens et resultats detailles des villes francaises issus du rapport paru en octobre 2002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-10-15

    Air pollution is a public health problem, in spite of more severe norms in matter of emissions rates, a stricter surveillance of the atmospheric pollution and the decrease of levels of some atmospheric pollutants. this situation has lead to the creation of a programme A.p.h.e.i.s. in 1999, in order to supply to Europeans authorities information on air pollution. In the report are presented the results of E.I.S. (evaluation of sanitary impact) made in towns.

  12. Modern toxic antipersonnel projectiles.

    Science.gov (United States)

    Gaillard, Yvan; Regenstreif, Philippe; Fanton, Laurent

    2014-12-01

    gun in the present day, however, shows that these weapons are still present. The possibility that one might be used to spray a charge of cyanide is still very real, especially as it would not be very difficult for an informed amateur to produce homemade toxic ammunition by adapting existing civil or military cartridges.

  13. Air Pollution

    Science.gov (United States)

    Air pollution is a mixture of solid particles and gases in the air. Car emissions, chemicals from factories, dust, ... a gas, is a major part of air pollution in cities. When ozone forms air pollution, it's ...

  14. Air pollution and public health: emerging hazards and improved understanding of risk.

    Science.gov (United States)

    Kelly, Frank J; Fussell, Julia C

    2015-08-01

    Despite past improvements in air quality, very large parts of the population in urban areas breathe air that does not meet European standards let alone the health-based World Health Organisation Air Quality Guidelines. Over the last 10 years, there has been a substantial increase in findings that particulate matter (PM) air pollution is not only exerting a greater impact on established health endpoints, but is also associated with a broader number of disease outcomes. Data strongly suggest that effects have no threshold within the studied range of ambient concentrations, can occur at levels close to PM2.5 background concentrations and that they follow a mostly linear concentration-response function. Having firmly established this significant public health problem, there has been an enormous effort to identify what it is in ambient PM that affects health and to understand the underlying biological basis of toxicity by identifying mechanistic pathways-information that in turn will inform policy makers how best to legislate for cleaner air. Another intervention in moving towards a healthier environment depends upon the achieving the right public attitude and behaviour by the use of optimal air pollution monitoring, forecasting and reporting that exploits increasingly sophisticated information systems. Improving air quality is a considerable but not an intractable challenge. Translating the correct scientific evidence into bold, realistic and effective policies undisputedly has the potential to reduce air pollution so that it no longer poses a damaging and costly toll on public health.

  15. Geographical information system and environmental epidemiology: a cross-sectional spatial analysis of the effects of traffic-related air pollution on population respiratory health

    Science.gov (United States)

    2011-01-01

    Background Traffic-related air pollution is a potential risk factor for human respiratory health. A Geographical Information System (GIS) approach was used to examine whether distance from a main road (the Tosco-Romagnola road) affected respiratory health status. Methods We used data collected during an epidemiological survey performed in the Pisa-Cascina area (central Italy) in the period 1991-93. A total of 2841 subjects participated in the survey and filled out a standardized questionnaire on health status, socio-demographic information, and personal habits. A variable proportion of subjects performed lung function and allergy tests. Highly exposed subjects were defined as those living within 100 m of the main road, moderately exposed as those living between 100 and 250 m from the road, and unexposed as those living between 250 and 800 m from the road. Statistical analyses were conducted to compare the risks for respiratory symptoms and diseases between exposed and unexposed. All analyses were stratified by gender. Results The study comprised 2062 subjects: mean age was 45.9 years for men and 48.9 years for women. Compared to subjects living between 250 m and 800 m from the main road, subjects living within 100 m of the main road had increased adjusted risks for persistent wheeze (OR = 1.76, 95% CI = 1.08-2.87), COPD diagnosis (OR = 1.80, 95% CI = 1.03-3.08), and reduced FEV1/FVC ratio (OR = 2.07, 95% CI = 1.11-3.87) among males, and for dyspnea (OR = 1.61, 95% CI = 1.13-2.27), positivity to skin prick test (OR = 1.83, 95% CI = 1.11-3.00), asthma diagnosis (OR = 1.68, 95% CI = 0.97-2.88) and attacks of shortness of breath with wheeze (OR = 1.67, 95% CI = 0.98-2.84) among females. Conclusion This study points out the potential effects of traffic-related air pollution on respiratory health status, including lung function impairment. It also highlights the added value of GIS in environmental health research. PMID:21362158

  16. A WET TALE: TOXICITY OF COMPLEX EFFLUENTS

    Science.gov (United States)

    This course covers standards, regulations, policy, guidance and technical aspects of implementing the whole effluent toxicity program. The curriculum incorporates rationale and information on WET test requirements from USEPA documents, such as the Technical Support Document for W...

  17. As Traffic Piles Up, So Does Air Pollution

    Science.gov (United States)

    ... 160914.html As Traffic Piles Up, So Does Air Pollution To minimize exposure, researchers recommend shutting windows and ... Doing so can reduce your exposure to toxic air pollution from a traffic jam by up to 76 ...

  18. Toxic compounds in honey.

    Science.gov (United States)

    Islam, Md Nazmul; Khalil, Md Ibrahim; Islam, Md Asiful; Gan, Siew Hua

    2014-07-01

    There is a wealth of information about the nutritional and medicinal properties of honey. However, honey may contain compounds that may lead to toxicity. A compound not naturally present in honey, named 5-hydroxymethylfurfural (HMF), may be formed during the heating or preservation processes of honey. HMF has gained much interest, as it is commonly detected in honey samples, especially samples that have been stored for a long time. HMF is a compound that may be mutagenic, carcinogenic and cytotoxic. It has also been reported that honey can be contaminated with heavy metals such as lead, arsenic, mercury and cadmium. Honey produced from the nectar of Rhododendron ponticum contains alkaloids that can be poisonous to humans, while honey collected from Andromeda flowers contains grayanotoxins, which can cause paralysis of limbs in humans and eventually leads to death. In addition, Melicope ternata and Coriaria arborea from New Zealand produce toxic honey that can be fatal. There are reports that honey is not safe to be consumed when it is collected from Datura plants (from Mexico and Hungary), belladonna flowers and Hyoscamus niger plants (from Hungary), Serjania lethalis (from Brazil), Gelsemium sempervirens (from the American Southwest), Kalmia latifolia, Tripetalia paniculata and Ledum palustre. Although the symptoms of poisoning due to honey consumption may differ depending on the source of toxins, most common symptoms generally include dizziness, nausea, vomiting, convulsions, headache, palpitations or even death. It has been suggested that honey should not be considered a completely safe food.

  19. 76 FR 38023 - Approval and Promulgation of Implementation Plans and Designations of Areas for Air Quality...

    Science.gov (United States)

    2011-06-29

    ... discretionary authority to address, as appropriate, disproportionate human health or environmental effects...)(2)). List of Subjects in 40 CFR Part 52 Environmental protection, Air pollution control... Development Section, Air Planning Branch, Air, Pesticides and Toxics Management Division, U.S....

  20. Joint EPA/UMTA/FEA strategy for urban transportation and air quality. Volume 4. Information data base: status of urban congestion, air pollution, and energy use. Literature review, 1964--1974

    Energy Technology Data Exchange (ETDEWEB)

    Krzyczkowski, R.; Henneman, S.S.; Putnam, E.S.; Usowicz, T.W.

    1974-12-01

    The objective of the study is to formulate a basis for the design of a joint program which would simultaneously improve urban mobility and air quality and conserve petroleum resources. This fourth volume contains INTERPLAN's initial definition of the transportation-related urban problems now faced by UMTA, EPA, and FEA, and their authority to cope with these problems. The current status of transportation-related urban congestion, air pollution, and energy usage is analyzed on a national level, and the future status likely to obtain if present trends continue unchecked is projected. Congestion and air pollution is also examined in four cities: Los Angeles, Philadelphia, Seattle, and Baltimore.

  1. Space-Based Internet of Things Applications Based on Integrated Ground-Air-Space Information Network%天地一体化信息网络天基物联网应用体系研究

    Institute of Scientific and Technical Information of China (English)

    曾业; 周永将

    2016-01-01

    天地一体化信息网络是国家重点工程之一,是未来我国信息时代的战略性公共信息基础设施。随着跨境电子商务、智能家居、智能航空管理等物联网应用的蓬勃发展,对发展天基物联网提出了急需。因此将天地一体化网络工程建设与天基物联网应用服务紧密结合非常重要。本文将主要对基于天地一体化信息网络工程的物联网应用体系进行研究,包括参考模型、网络架构、协议体系和软件系统等几个方面,为天地一体化信息网络工程的建设奠定基础。%As one of the key project in our country,the integrated ground-air-space information network will be the strategic infrastructure and technology in the coming information times. As the development of cross-border electronic commerce, smart home and intelligence air manages, the necessary on the development of space-based internet of things is presented, so it is significant to combine the building of integrated ground-air-space information network project with space-based internet of things applications. This paper focus on the research of space-based internet of things applications based on integrated ground-air-space information network, includes reference model, network architecture, software system and protocols architecture, and lay the foundation to build the integrated ground-air-space information network project.

  2. Air/liquid collectors

    DEFF Research Database (Denmark)

    Jensen, Søren Østergaard; Olesen, Ole; Kristiansen, Finn Harken

    1997-01-01

    This report determine efficiency equations for combined air/liquid solar collectors by measurements on to different air/liquid collectors. Equations which contain all relevant informations on the solar collectors. A simulation program (Kviksol) has been modified in order to be able to handle...

  3. Air Pollution, Teachers' Edition.

    Science.gov (United States)

    Lavaroni, Charles W.; O'Donnell, Patrick A.

    One of three in a series about pollution, this teacher's guide for a unit on air pollution is designed for use in junior high school grades. It offers suggestions for extending the information and activities contained in the textual material for students. Chapter 1 discusses the problem of air pollution and involves students in processes of…

  4. Toxic Amblyopia (Nutritional Amblyopia)

    Science.gov (United States)

    ... Contact Lenses Additional Content Medical News Toxic Amblyopia (Nutritional Amblyopia) By James Garrity, MD, Mayo Clinic NOTE: ... or methyl alcohol), antifreeze, or certain drugs. A nutritional deficiency or toxic substance is often the cause ...

  5. Toxic Picoplanktonic Cyanobacteria—Review

    OpenAIRE

    Natalia Jakubowska; Elżbieta Szeląg-Wasielewska

    2015-01-01

    Cyanobacteria of a picoplanktonic cell size (0.2 to 2.0 µm) are common organisms of both freshwater and marine ecosystems. However, due to their small size and relatively short study history, picoplanktonic cyanobacteria, in contrast to the microplanktonic cyanobacteria, still remains a poorly studied fraction of plankton. So far, only little information on picocyanobacteria toxicity has been reported, while the number of reports concerning their presence in ecosystems is increasing. Thus, th...

  6. The toxicity of inhaled methanol vapors

    Energy Technology Data Exchange (ETDEWEB)

    Kavet, R.; Nauss, K.M. (Environmental Research Information, Inc., Palo Alto, CA (USA))

    1990-01-01

    Methanol could become a major automotive fuel in the U.S., and its use may result in increased exposure of the public to methanol vapor. Nearly all of the available information on methanol toxicity in humans relates to the consequences of acute, rather than chronic, exposures. Acute methanol toxicity evolves in a well-understood pattern and consists of an uncompensated metabolic acidosis with superimposed toxicity to the visual system. The toxic properties of methanol are rooted in the factors that govern both the conversion of methanol to formic acid and the subsequent metabolism of formate to carbon dioxide in the folate pathway. In short, the toxic syndrome sets in if formate generation continues at a rate that exceeds its rate of metabolism. Current evidence indicates that formate accumulation will not challenge the metabolic capacity of the folate pathway at the anticipated levels of exposure to automotive methanol vapor.117 references.

  7. Toxicities of selected substances to freshwater biota

    Energy Technology Data Exchange (ETDEWEB)

    Hohreiter, D.W.

    1980-05-01

    The amount of data available concerning the toxicity of various substances to freshwater biota is so large that it is difficult to use in a practical situation, such as environmental impact assessment. In this document, summary tables are presented showing acute and/or chronic toxicity of selected substances for various groups of aquatic biota. Each entry is referenced to its original source so that details concerning experimental conditions may be consulted. In addition, general information concerning factors modifying toxicity, synergisms, evidence of bioaccumulation, and water quality standards and criteria for the selected substances is given. The final table is a general toxicity table designed to provide an easily accessible and general indication of toxicity of selected substances in aquatic systems.

  8. Influences of Networked Command Information System on Effectiveness of Over-the-horizon Air Combat%网络化指挥信息系统对超视距空战效能影响分析∗

    Institute of Scientific and Technical Information of China (English)

    巴宏欣; 王俊; 陈亚飞

    2015-01-01

    Aimming at the problem of over⁃the⁃horizon air combat effectiveness evaluation without considering the support of networked command information system, the effect of networked command information system on over⁃the⁃horizon air combat is analyzed in this paper. Based on the method of two⁃step adjudication for air war, the first⁃shot index model, air⁃to⁃air mis⁃sile damage effectiveness model and combat aircraft lost rate model are improved. A numerical example shows that the models are valid and networked command information system promotes the operational effectiveness of over⁃the⁃horizon air combat ev⁃idently. The results can provide reference and support for operational means study of aviation.%针对目前超视距空战效能评估中没有充分考虑网络化指挥信息系统的支撑等问题,研究分析了网络化指挥信息系统对超视距空战效能的影响,在借鉴空战两步裁定法的基础上,改进了先敌发射概率模型、导弹毁伤能力模型,以及超视距空战双方总损耗及交换比计算方法。仿真算例验证了改进后的模型与方法的有效性和网络化指挥信息对超视距空战效能的提升,可为航空兵部队的战法研究提供参考和借鉴。

  9. Air Pollution Primer. Revised Education.

    Science.gov (United States)

    Corman, Rena

    This revised and updated book is written to inform the citizens on the nature, causes, and effects of air pollution. It is written in terms familiar to the layman with the purpose of providing knowledge and motivation to spur community action on clean air policies. Numerous charts and drawings are provided to support discussion of air pollution…

  10. Acute toxicity and toxic interaction of chromium and nickel to common guppy Poecilia reticulata (Peters)

    Energy Technology Data Exchange (ETDEWEB)

    Khangarot, B.S.; Ray, P.K. (Industrial Toxicology Research Centre, Lucknow (India))

    1990-06-01

    The acute toxicity of heavy metals in combination to the common guppy has been reported. Information on the combined effects of chromium and nickel to fish is rather scarce. Toxicity of nickel and chromium to fish is generally low. These two elements are usually less toxic than silver, cadmium, copper and thallium; depending on test conditions, these may also be less hazardous than zinc, lead and arsenic. The present study was undertaken to investigate the acute toxicity of Ni and Cr singly and the toxic interaction of these two metal ions on survival of the common guppy, Poecilia reticulata (Peters). This species was selected for static bioassays because it can be easily cultured and raised under laboratory conditions through a complete life cycle, and it is one of the most common fish used for laboratory toxicity studies.

  11. Rapid toxicity screening of gasification ashes.

    Science.gov (United States)

    Zhen, Xu; Rong, Le; Ng, Wei Cheng; Ong, Cynthia; Baeg, Gyeong Hun; Zhang, Wenlin; Lee, Si Ni; Li, Sam Fong Yau; Dai, Yanjun; Tong, Yen Wah; Neoh, Koon Gee; Wang, Chi-Hwa

    2016-04-01

    The solid residues including bottom ashes and fly ashes produced by waste gasification technology could be reused as secondary raw materials. However, the applications and utilizations of these ashes are very often restricted by their toxicity. Therefore, toxicity screening of ash is the primary condition for reusing the ash. In this manuscript, we establish a standard for rapid screening of gasification ashes on the basis of in vitro and in vivo testing, and henceforth guide the proper disposal of the ashes. We used three different test models comprising human cell lines (liver and lung cells), Drosophila melanogaster and Daphnia magna to examine the toxicity of six different types of ashes. For each ash, different leachate concentrations were used to examine the toxicity, with C0 being the original extracted leachate concentration, while C/C0 being subsequent diluted concentrations. The IC50 for each leachate was also quantified for use as an index to classify toxicity levels. The results demonstrated that the toxicity evaluation of different types of ashes using different models is consistent with each other. As the different models show consistent qualitative results, we chose one or two of the models (liver cells or lung cells models) as the standard for rapid toxicity screening of gasification ashes. We may classify the gasification ashes into three categories according to the IC50, 24h value on liver cells or lung cells models, namely "toxic level I" (IC50, 24h>C/C0=0.5), "toxic level II" (C/C0=0.05IC50, 24hIC50, 24hinformative approach can help to determine the toxic effects of various types of ashes generated in gasification plants every day. Subsequently, appropriate disposal methods can be recommended for each toxicity category.

  12. 基于不完全信息空战的火力分配建模与应用%Research on Weapon-Target Assignment Modeling and Application Based on Incomplete Information Air Combat

    Institute of Scientific and Technical Information of China (English)

    隋永华; 郭雷; 俞利新; 王海晏

    2012-01-01

    To solve the problem of weapon-target assignment in an incomplete information air combat, the common weapon-target assignment model is analized, the defect of which is pointed out, and an improved weapon-target assignment model is built. The computation method of the key arguments of the model is proposed according to the character of incomplete information air combat. The improved mode can work efficiently based on the limited papameters obtained easily in the condition of incomplete information. Finally,the efficiency of the model is validated through a typical air combat example.%为了解决不完全信息空战中的火力分配问题,分析了常规空战火力分配模型,指出了其中的不足,建立了一种改进的火力分配模型.针对不完全信息空战特点,给出了其中关键参数的确定方法.该改进模型可有效利用战机在不完全信息条件下容易获取的有限参数进行火力分配,具有很强的实用性.最后通过典型应用实例验证了模型的有效性.

  13. A Breath of Fresh Air

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Have you ever driven by a sewage-treatment plant and noticed a rotten-eggstink? Air-quality requirements force these plants touse devices called chemical scrubbers to eliminate malodorous hydrogen sulfide from the gases createdby bacteria in sewageslurry. The process works,but it's expensive and depends on filtering gasthrough toxic chemicalssuch as lye and bleach.

  14. Relation of air pollution with epidemiology of respiratory diseases in isfahan, Iran from 2005 to 2009

    Directory of Open Access Journals (Sweden)

    Maasoumeh Rashidi

    2013-01-01

    Full Text Available Background: National Institute of Environmental Health Sciences (NIEHS scientists shows that long-term exposure to air pollutants increases the risk of respiratory diseases such as allergies, asthma, chronic obstructive pulmonary disease, and lung cancer. Children and the elderly are particularly vulnerable to the health effects of ozone, fine particles, and other airborne toxicants. Air pollution factors are considered as one of the underlying causes of respiratory diseases. This study aimed to determine the association of respiratory diseases documented in medical records and air pollution (Map distribution of accumulation in Isfahan province, Iran. By plotting the prevalence and spatial distribution maps, important differences from different points can be observed. Materials and Methods: The geographic information system (GIS, pollutant standards index (PSI measurements, and remote Sensing (RS technology were used after entering data in the mapping information table; spatial distribution was mapped and distribution of Geographical Epidemiology of Respiratory Diseases in Isfahan province (Iran was determined in this case study from 2005 to 2009. Results: Space with tracing the distribution of respiratory diseases was scattered based on the distribution of air pollution in the points is an important part of this type of diseases in Isfahan province where air pollution was more abundant. Conclusion: The findings of this study emphasis on the importance of preventing the exposure to air pollution, and to control air pollution product industries, to improve work environmental health, and to increase the health professionals and public knowledge in this regard.

  15. Streptococcal toxic shock syndrome

    OpenAIRE

    Gvozdenović Ljiljana; Pasternak Janko; Milovanović Stanislav; Ivanov Dejan; Milić Saša

    2010-01-01

    Introduction. Streptococcal toxic shock syndrome is now recognized as a toxin-mediated, multisystem illness. It is characterized by an early onset of shock with multiorgan failure and continues to be associated with high morbidity and mortality, caused by group A Streptococcus pyogenes. The symptoms for staphylococcal and streptococcal toxic shock syndrome are similar. Streptococcal toxic shock syndrome was not well described until 1993, when children who had suffered from varicella pre...

  16. CHEMICAL TOXICITY OF URANIUM

    Directory of Open Access Journals (Sweden)

    Sermin Cam

    2007-06-01

    Full Text Available Uranium, occurs naturally in the earth’s crust, is an alpha emitter radioactive element from the actinide group. For this reason, U-235 and U-238, are uranium isotopes with long half lives, have got radiological toxicity. But, for natural-isotopic-composition uranium (NatU, there is greater risk from chemical toxicity than radiological toxicity. When uranium is get into the body with anyway, also its chemical toxicity must be thought. [TAF Prev Med Bull 2007; 6(3.000: 215-220

  17. Gulf of Mexico Air Quality: CALIPSO Support for Gulf of Mexico Air Quality Relating to the Deepwater Horizon Oil Spill

    Science.gov (United States)

    Nguyen, Myngoc T.; Lapointe, Stephen; Jennings, Brittney; Zoumplis, Angela

    2011-01-01

    On April 20, 2010, an oil platform belonging to BP exploded and leaked a huge volume of oil into the Gulf of Mexico. In an effort to control the spread of the oil, BP applied dispersants such as Corexit and conducted in-situ burnings of the oil. This catastrophe created a complex chain of events that affected not only the fragile water and land ecosystems, but the humans who breathe the air every day. Thousands of people were exposed to fumes associated with oil vapors from the spill, burning of the oil, and the toxic mixture of dispersants. While aiding in clean-up efforts, local fishermen were directly exposure to fumes when working on the Gulf. A notable amount of Gulf Coast residents were also exposed to the oil fumes as seasonal southeasterly winds blew vapors toward land. The Volatile Organic Compounds (VOC) found in oil vapors include: benzene, toluene, ethyl benzene, xylene, naphthalene, hydrogen sulfide and particulate matter (PM). Increases in water temperature and sunlight due to the summer season allow for these VOCs and PM to evaporate into the air more rapidly. Aside from the VOCs found in oil vapors, the dispersant being used to break up the oil is highly toxic and is thought to be even more toxic than the oil itself (EPA website, 2010). To protect human health, the environment, and to make informed policy decisions relevant to the spill, the EPA Region 6 has continuously monitored the affected areas carefully for levels of pollutants in the outdoor air that are associated with petroleum products and the burning of oil along the coast. In an effort to prevent, prepare for, and respond to future oil spills that occur in and around inland waters of the United States, the EPA has been working with local, state, and federal response partners. Air quality measurements were collected by the EPA at five active monitoring systems stationed along the coast.

  18. 77 FR 24440 - Approval and Promulgation of Air Quality Implementation Plans; North Carolina; Annual Emissions...

    Science.gov (United States)

    2012-04-24

    ... Branch, Air, Pesticides and Toxics Management Division, U.S. Environmental Protection Agency, Region 4..., Chief, Regulatory Development Section, Air Planning Branch, Air, Pesticides and Toxics Management...-8960. Such deliveries are only accepted during the Regional Office's normal hours of operation....

  19. 78 FR 6736 - Revisions to the California State Implementation Plan, Placer County Air Pollution Control District

    Science.gov (United States)

    2013-01-31

    ... taking direct final action to approve revisions to the Placer County Air Pollution Control District... regulations that control VOCs, NO X , and PM emissions. Rules 301-306 limit emissions of air pollutants... Toxic Control Measure to Reduce Emissions of Toxic Air Contaminants from Outdoor Residential...

  20. Mechanisms of Silver Nanoparticle Toxicity

    DEFF Research Database (Denmark)

    Foldbjerg, Rasmus

    nanometers. At this size, materials begin to exhibit unique properties that affect physical, chemical, and biological behavior. However, the same characteristics which make nanomaterials attractive for exploitation in new products have led to concerns that nanomaterials may pose a risk for humans...... to their anti-microbial properties, high electrical conductivity, and optical properties. Information about the mechanisms involved in the cytotoxicity of Ag NPs is important in order to evaluate the potential hazards posed by these particles. Several studies have suggested oxidative stress to play a major role...... in NP toxicity. But, to what degree and by which mechanism Ag NPs cause oxidative stress in cells is unresolved. The present PhD project set out to explore the cellular mechanisms involved in the toxicity of Ag NPs in vitro. In particular, the study aimed to assess the induction of cellular pathways...

  1. [Air quality monitoring on the International Space Station].

    Science.gov (United States)

    Pakhomova, A A; Mukhamedieva, L N; Mikos, K N

    2006-01-01

    Chemical contamination of air in space cabins occurs mainly due to permanent offgassing of equipment and materials, and leaks. Methods and means of qualitative and quantitative air monitoring on the ISS are powerful enough as for routine so emergency (e.g. local fire, toxic leak) air control. The ISS air quality has suited to the adopted standards and crew safety requirements. Yet, there is a broad field of action toward improvement of the space cabin air monitoring.

  2. Psychiatric aspects of air pollution.

    Science.gov (United States)

    Lundberg, A

    1996-02-01

    Psychological and toxic effects of air pollution can lead to psychiatric symptoms, including anxiety and changes in mood, cognition, and behavior. Increased levels of some air pollutants are accompanied by an increase in psychiatric admissions and emergency calls and, in some studies, by changes in behavior and a reduction in psychological well-being. Numerous toxic pollutants interfere with the development and adult functioning of the nervous system. Manifestations are often insidious or delayed, but they can provide a more sensitive indicator of toxic effects than cancer rates or mortality data. Other medical effects of air pollution, such as asthma, can indirectly affect psychological health. The sick building syndrome and multiple chemical sensitivity are conditions with toxicologic and psychiatric aspects. Psychosocial stress can cause symptoms similar to those of organic mental disorders. Reactions to stress depend on cultural, individual, and situational variables. We must understand these factors to be able to alleviate and prevent the consequences of environmental trauma. Expanded research is recommended in three main areas: (1) how people perceive and cope with environmental health risks, (2) the effects of air pollution on behavior and neuropsychological functioning, and (3) neurotoxicologic evaluation of air pollutants with both behavioral and in vitro studies.

  3. Internet Use Patterns, Acceptance Levels. and Policy Recommendations: An Information Technology Infusion Approach to the Internet and the United States Air Force.

    Science.gov (United States)

    1996-12-01

    well as policy recommendations regarding Internet use in the Air Force. The research provides substantial evidence that Internet technology is not being...highly infused at the headquaners-level than it is at base-level. This research also demonstrates that supervisory support for Internet use positively

  4. Pyridostigmine Synergistic Toxicity Study.

    Science.gov (United States)

    1995-05-31

    AND DEET IN THE LABORATORY RAT 1. Executive Sum m ary .............................................................................................. 2 2...TOXICOLOGICAL STUDY 75-48-2665 ACUTE ORAL TOXICITY STUDY OF PYRIDOSTIGMINE BROMIDE. PERMETHRIN. AND DEET IN THE LABORATORY RAT 1. REFERENCES: See Appendix A... LABORATORY RAT 1. PURPOSE: The purpose of this study was to determine potential toxic interactions when pyridostigmine bromide. permethrin. and DEET are given

  5. Mechanisms of Phosphine Toxicity

    Directory of Open Access Journals (Sweden)

    Nisa S. Nath

    2011-01-01

    Full Text Available Fumigation with phosphine gas is by far the most widely used treatment for the protection of stored grain against insect pests. The development of high-level resistance in insects now threatens its continued use. As there is no suitable chemical to replace phosphine, it is essential to understand the mechanisms of phosphine toxicity to increase the effectiveness of resistance management. Because phosphine is such a simple molecule (PH3, the chemistry of phosphorus is central to its toxicity. The elements above and below phosphorus in the periodic table are nitrogen (N and arsenic (As, which also produce toxic hydrides, namely, NH3 and AsH3. The three hydrides cause related symptoms and similar changes to cellular and organismal physiology, including disruption of the sympathetic nervous system, suppressed energy metabolism and toxic changes to the redox state of the cell. We propose that these three effects are interdependent contributors to phosphine toxicity.

  6. Mechanisms of phosphine toxicity.

    Science.gov (United States)

    Nath, Nisa S; Bhattacharya, Ishita; Tuck, Andrew G; Schlipalius, David I; Ebert, Paul R

    2011-01-01

    Fumigation with phosphine gas is by far the most widely used treatment for the protection of stored grain against insect pests. The development of high-level resistance in insects now threatens its continued use. As there is no suitable chemical to replace phosphine, it is essential to understand the mechanisms of phosphine toxicity to increase the effectiveness of resistance management. Because phosphine is such a simple molecule (PH(3)), the chemistry of phosphorus is central to its toxicity. The elements above and below phosphorus in the periodic table are nitrogen (N) and arsenic (As), which also produce toxic hydrides, namely, NH(3) and AsH(3). The three hydrides cause related symptoms and similar changes to cellular and organismal physiology, including disruption of the sympathetic nervous system, suppressed energy metabolism and toxic changes to the redox state of the cell. We propose that these three effects are interdependent contributors to phosphine toxicity.

  7. Mechanisms of Phosphine Toxicity

    Science.gov (United States)

    Nath, Nisa S.; Bhattacharya, Ishita; Tuck, Andrew G.; Schlipalius, David I.; Ebert, Paul R.

    2011-01-01

    Fumigation with phosphine gas is by far the most widely used treatment for the protection of stored grain against insect pests. The development of high-level resistance in insects now threatens its continued use. As there is no suitable chemical to replace phosphine, it is essential to understand the mechanisms of phosphine toxicity to increase the effectiveness of resistance management. Because phosphine is such a simple molecule (PH3), the chemistry of phosphorus is central to its toxicity. The elements above and below phosphorus in the periodic table are nitrogen (N) and arsenic (As), which also produce toxic hydrides, namely, NH3 and AsH3. The three hydrides cause related symptoms and similar changes to cellular and organismal physiology, including disruption of the sympathetic nervous system, suppressed energy metabolism and toxic changes to the redox state of the cell. We propose that these three effects are interdependent contributors to phosphine toxicity. PMID:21776261

  8. Air quality in Europe - 2012 report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-09-15

    This report presents an overview and analysis of the status and trends of air quality in Europe based on concentration measurements in ambient air and data on anthropogenic emissions and trends from 2001 - when mandatory monitoring of ambient air concentrations of selected pollutants first produced reliable air quality information - to 2010. (Author)

  9. SYSTEMIC TOXIC REACTIONS TO LOCAL ANESTHETICS

    Science.gov (United States)

    Moore, Daniel C.; Green, John

    1956-01-01

    The topical use of anesthetic agents involves an element of risk. Systemic toxic reactions are rare, but they do occur and may result in death. When a reaction occurs from a topical application, it usually progresses rapidly to respiratory and cardiovascular collapse, and thus therapy must be instituted with more haste to avoid deaths. Fatal systemic toxic reactions from topically administered anesthetic drugs are, in effect, usually not due to well informed use of the drug but to misuse owing to less than complete understanding of absorption. Emphasis is placed on the causes, prophylaxis and treatment of severe systemic toxic reactions which follow the topical application of local anesthetic drugs. If systemic toxic reactions resulting from a safe dose of a local anesthetic agent are correctly treated, there will usually follow an uneventful recovery rather than a catastrophe. PMID:13343009

  10. The Air Force Records Management Program: A Paradigm Shift from Compliance to Guiding Principles in an Ever-Changing Information Environment

    Science.gov (United States)

    2014-06-22

    AFRO, Command and Agency Records Managers ( CRM /ARM), Base Records Managers (BRM), Unit Commanders/Directors, and Unit Record Managers (URM)” (Air Force... management is implemented in the USAF environment, it is important to recognize the customer , whom RM is designed to serve and receives the final benefit...how much power these managers wield. In this case, a close working relationship with their leadership and understanding of the charge at hand is

  11. Toxic Shock Syndrome (For Teens)

    Science.gov (United States)

    ... Surgery? A Week of Healthy Breakfasts Shyness Toxic Shock Syndrome KidsHealth > For Teens > Toxic Shock Syndrome Print ... it, then take some precautions. What Is Toxic Shock Syndrome? If you're a girl who's had ...

  12. Air Force Office of Scientific Research, May/Jun 98 Research Highlights.

    Science.gov (United States)

    1998-06-01

    quality of airfield pavements, proteins that protect against toxicity, compact laser development , scientist and engineer exchange program and technology transitions that benefit Air Force operations.

  13. Toxic releases and risk disparity: a spatiotemporal model of industrial ecology and social empowerment.

    Science.gov (United States)

    Aoyagi, Hannah; Ogunseitan, Oladele A

    2015-06-02

    Information-based regulations (IBRs) are founded on the theoretical premise that public participation in accomplishing policy goals is empowered by open access to information. Since its inception in 1988, the Toxics Release Inventory (TRI) has provided the framework and regulatory impetus for the compilation and distribution of data on toxic releases associated with industrial development, following the tenets of IBR. As TRI emissions are reputed to disproportionately affect low-income communities, we investigated how demographic characteristics are related to change in TRI emissions and toxicity risks between 1989 and 2002, and we sought to identify factors that predict these changes. We used local indicators of spatial association (LISA) maps and spatial regression techniques to study risk disparity in the Los Angeles urban area. We also surveyed 203 individuals in eight communities in the same region to measure the levels of awareness of TRI, attitudes towards air pollution, and general environmental risk. We discovered, through spatial lag models, that changes in gross and toxic emissions are related to community ethnic composition, poverty level, home ownership, and base 1989 emissions (R-square=0.034-0.083). We generated a structural equation model to explain the determinants of social empowerment to act on the basis of environmental information. Hierarchical confirmatory factor analysis (HCFA) supports the theoretical model that individual empowerment is predicted by risk perception, worry, and awareness (Chi-square=63.315, p=0.022, df=42). This study provides strong evidence that spatiotemporal changes in regional-scale environmental risks are influenced by individual-scale empowerment mediated by IBRs.

  14. 信息安全视角下人防面临的威胁分析%Analysis on the Civil Air Defense Threat under the Perspective of Information Security

    Institute of Scientific and Technical Information of China (English)

    平亮

    2015-01-01

    信息防护是人民防空安全防护的重要组成部分,涉及的内容广泛,是一项系统工程,包括物理层安全、系统层安全、网络层安全和管理层安全等.%Information protection is an important part of the civil air defense. It is a system engineering that involves extensively, generally includes the physical security, system security, network layer, application layer and security management, etc.

  15. Natural toxicants in foods.

    Science.gov (United States)

    Coon, J M

    1975-09-01

    Food constitutes the most complex part of our chemical environment. Naturally occurring substances in food, such as goitrogens and estrogens, are toxicants. However, there is a difference of degree between toxicity and hazard, and the hazard to man in normal good health from naturally occurring toxicants in food is usually slight, because of (a) the small concentrations and (b) antagonistic interactions between toxicants which provide "safety in numbers." Hazard from foods may indeed exist under some circumstances, such as the presence of abnormal contaminants, ingestion of abnormal amounts, or abnormal susceptibility existing in some disease states. However, the major hazards of the dinner table can ordinarily be ascribed to careless food handling, unbalanced or fad diets, or overeating.

  16. Toxicity Reference Database

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Toxicity Reference Database (ToxRefDB) contains approximately 30 years and $2 billion worth of animal studies. ToxRefDB allows scientists and the interested...

  17. Aspects of aluminum toxicity

    Energy Technology Data Exchange (ETDEWEB)

    Hewitt, C.D.; Savory, J.; Wills, M.R. (Univ. of Virginia Health Sciences Center, Charlottesville (USA))

    1990-06-01

    Aluminum is the most abundant metal in the earth's crust. The widespread occurrence of aluminum, both in the environment and in foodstuffs, makes it virtually impossible for man to avoid exposure to this metal ion. Attention was first drawn to the potential role of aluminum as a toxic metal over 50 years ago, but was dismissed as a toxic agent as recently as 15 years ago. The accumulation of aluminum, in some patients with chronic renal failure, is associated with the development of toxic phenomena; dialysis encephalopathy, osteomalacic dialysis osteodystrophy, and an anemia. Aluminum accumulation also occurs in patients who are not on dialysis, predominantly infants and children with immature or impaired renal function. Aluminum has also been implicated as a toxic agent in the etiology of Alzheimer's disease, Guamiam amyotrophic lateral sclerosis, and parkinsonism-dementia. 119 references.

  18. Toxicity of lunar dust

    CERN Document Server

    Linnarsson, Dag; Fubini, Bice; Gerde, Per; Karlsson, Lars L; Loftus, David J; Prisk, G Kim; Staufer, Urs; Tranfield, Erin M; van Westrenen, Wim

    2012-01-01

    The formation, composition and physical properties of lunar dust are incompletely characterised with regard to human health. While the physical and chemical determinants of dust toxicity for materials such as asbestos, quartz, volcanic ashes and urban particulate matter have been the focus of substantial research efforts, lunar dust properties, and therefore lunar dust toxicity may differ substantially. In this contribution, past and ongoing work on dust toxicity is reviewed, and major knowledge gaps that prevent an accurate assessment of lunar dust toxicity are identified. Finally, a range of studies using ground-based, low-gravity, and in situ measurements is recommended to address the identified knowledge gaps. Because none of the curated lunar samples exist in a pristine state that preserves the surface reactive chemical aspects thought to be present on the lunar surface, studies using this material carry with them considerable uncertainty in terms of fidelity. As a consequence, in situ data on lunar dust...

  19. Environmental impact by toxic compounds from waste treatment; Miljoepaaverkan fraan toxiska aemnen vid hantering av avfall

    Energy Technology Data Exchange (ETDEWEB)

    Loefblad, Gun; Bisaillon, Mattias; Sundberg, Johan (Profu AB (Sweden))

    2010-07-01

    The study deals with emissions of toxic compounds from waste treatment to the environment with the aim of improving the state of knowledge and to find a way of describing the environmental impact from these substances. Toxicity is one of a number of environmental aspects necessary to address in the planning of waste treatment and in the daily waste treatment routines in order to fulfill the environmental objective A Non-Toxic Environment and other environmental requirements. The study includes waste to incineration, composting and anaerobic digestion. A comparison between methods were made for biological household waste. According to our study, the compounds of importance for waste treatment are metals and persistent organic compounds. These tend to bioaccumulate and enrich in food chains. The substances are important for the environmental objective A Non-Toxic Environment. In a first step the compounds chosen in this study may be suggested for describing toxicity from waste treatment: As, Cd, Cu, Hg, Pb, dioxin, PCB, the phthalate DEHP and the brominated flame retardant HBCDD. Other substances may be added to the list in a next step from up-dated and quality-assured characterisation factors or from other requirements or preferences. There is a limited knowledge on toxic compounds in waste flows and in different environmental compartments. More data are available for metals than for organic substances. There is also a limited knowledge on the fate of the compounds during the waste treatment processes. Most information is found for incineration. During composting and anaerobic digestion the metals will mainly be emitted to the environment by use of the compost and the anaerobic digestion residue. Organic substances will to some extent be degraded during the processes. However, there are gaps of knowledge to fill for the further work on estimating toxic emissions. There is mainly a need for more extensive data on toxic compounds in waste and their variations. A test

  20. Information on the Interstate Transport Good Neighbor Provision for the 2012 Fine Particulate Matter (PM) National Ambient Air Quality Standards (NAAQS) under Clean Air Act (CAA) Section 110(a)(2)(D)(i)(I)

    Science.gov (United States)

    The purpose of this March 2016 memorandum is to provide information to EPA regional offices and states as they develop and review SIPs that address the interstate transport Good Neighbor provision as it pertains to the PM2.5 NAAQS

  1. Mechanisms of Phosphine Toxicity

    OpenAIRE

    Nisa S. Nath; Ishita Bhattacharya; Andrew G. Tuck; Schlipalius, David I.; Paul R. Ebert

    2011-01-01

    Fumigation with phosphine gas is by far the most widely used treatment for the protection of stored grain against insect pests. The development of high-level resistance in insects now threatens its continued use. As there is no suitable chemical to replace phosphine, it is essential to understand the mechanisms of phosphine toxicity to increase the effectiveness of resistance management. Because phosphine is such a simple molecule (PH3), the chemistry of phosphorus is central to its toxicity...

  2. Toxic Hazards Research Unit Annual Technical Report: 1984

    Science.gov (United States)

    1984-09-01

    Holland, New York, 1980. Boyd, M. R., L. T. Burka, T. M. Harris, and B. J. Wilson, (1973), Lung- toxic furanoterpenoids produced by sweet potatoes ( IPOMOEA ...AFAMRL-TR-84-00 1 NNTRI-84-41 AD-A147 857 TOXIC HAZARDS RESEARCH UNIT ANNUAL TECHNICAL REPORT: � J. D. MACEIWEN E. H. VERNOT UNIVERSITY OF...ER * BRUCE 0. s’rUART, PhD * Director Toxic Hazards Division * .Air Force Aerospace Medical Research La racory SECURITY CLASSI FICA TI0N OF THIS PAGE

  3. Streptococcal toxic shock syndrome

    Directory of Open Access Journals (Sweden)

    Gvozdenović Ljiljana

    2010-01-01

    Full Text Available Introduction. Streptococcal toxic shock syndrome is now recognized as a toxin-mediated, multisystem illness. It is characterized by an early onset of shock with multiorgan failure and continues to be associated with high morbidity and mortality, caused by group A Streptococcus pyogenes. The symptoms for staphylococcal and streptococcal toxic shock syndrome are similar. Streptococcal toxic shock syndrome was not well described until 1993, when children who had suffered from varicella presented roughly 2-4 weeks later with a clinical syndrome highly suggestive of toxic shock syndrome. Characteristics, complications and therapy. It is characterized by a sudden onset of fever, chills, vomiting, diarrhea, muscle aches and rash. It can rapidly progress to severe and intractable hypotension and multisystem dysfunction. Almost every organ system can be involved. Complications of streptococcal toxic shock syndrome may include kidney failure, liver failure and even death. Crystalloids and inotropic agents are used to treat the hypovolemic shock aggressively, with close monitoring of the patient’s mean arterial pressure and central venous pressure. An immediate and aggressive management of hypovolemic shock is essential in streptococcal toxic shock syndrome. Targeted antibiotics are indicated; penicillin or a betalactam antibiotic is used for treating group A streptococci, and clindamycin has emerged as a key portion of the standard treatment.

  4. Seneca Compressed Air Energy Storage (CAES) Project

    Energy Technology Data Exchange (ETDEWEB)

    None

    2012-11-30

    This document provides specifications for the process air compressor for a compressed air storage project, requests a budgetary quote, and provides supporting information, including compressor data, site specific data, water analysis, and Seneca CAES value drivers.

  5. Atmospheric emissions and air quality impacts from natural gas production and use.

    Science.gov (United States)

    Allen, David T

    2014-01-01

    The US Energy Information Administration projects that hydraulic fracturing of shale formations will become a dominant source of domestic natural gas supply over the next several decades, transforming the energy landscape in the United States. However, the environmental impacts associated with fracking for shale gas have made it controversial. This review examines emissions and impacts of air pollutants associated with shale gas production and use. Emissions and impacts of greenhouse gases, photochemically active air pollutants, and toxic air pollutants are described. In addition to the direct atmospheric impacts of expanded natural gas production, indirect effects are also described. Widespread availability of shale gas can drive down natural gas prices, which, in turn, can impact the use patterns for natural gas. Natural gas production and use in electricity generation are used as a case study for examining these indirect consequences of expanded natural gas availability.

  6. Trials of the use of high pressure compressed air for coal winning in soutirage faces. Final report; Ensayo de arranque de carbon con aire comprimido de alta presion en explotaciones por sutiraje. Informe final

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    The company Hullera Vasco Leones (HVL) is trying to improve the results of its exploitations by means of soutirage (sublevel caving), looking for maximum vertical concentration of the product. The limitation of the present systems necessitates the use of other methods of breaking the coal block. For this reason, a trial of the high pressure compressed air blasting (DACAP) technique would appear to be appropriate. This offers the outstanding advantage of increasing the height of the coal obtained by soutirage. HVL has divided the investigation into two stages. Firstly, to study the feasibility study recommended the use of the Competidora method, using the DACAP technique for the soutirage, duplicating the distance between sublevels. The foreseen improvements are a cost reduction of 17% and an output increase of almost 9%. The trial stage of this operation started in the first six months of 1992 and results were established in relation to: working variables optimization, improvements in production and productivity, a better percentage of coal recovery and cost reductions. This document summarises the work done and the results obtained from the project.

  7. Radioactive air sampling methods

    CERN Document Server

    Maiello, Mark L

    2010-01-01

    Although the field of radioactive air sampling has matured and evolved over decades, it has lacked a single resource that assimilates technical and background information on its many facets. Edited by experts and with contributions from top practitioners and researchers, Radioactive Air Sampling Methods provides authoritative guidance on measuring airborne radioactivity from industrial, research, and nuclear power operations, as well as naturally occuring radioactivity in the environment. Designed for industrial hygienists, air quality experts, and heath physicists, the book delves into the applied research advancing and transforming practice with improvements to measurement equipment, human dose modeling of inhaled radioactivity, and radiation safety regulations. To present a wide picture of the field, it covers the international and national standards that guide the quality of air sampling measurements and equipment. It discusses emergency response issues, including radioactive fallout and the assets used ...

  8. Physical conditions affecting pyrethroid toxicity in arthropods.

    NARCIS (Netherlands)

    Jagers op Akkerhuis, G.A.J.M.

    1993-01-01

    The aim of this thesis was to obtain mechanistic information about how the toxicity of pesticides in the field is affected by physical factors, pesticide bioavailability and arthropod behaviour. The pyrethroid insecticide deltamethrin and linyphiid spiders were selected as pesticide-effect model. In

  9. Rhabdomyolysis: a manifestation of cyclobenzaprine toxicity

    Directory of Open Access Journals (Sweden)

    Chabria Shiven B

    2006-07-01

    Full Text Available Abstract A case of cyclobenzaprine (flexeril overdose and the resultant rhabdomyolysis is presented. A review of the range of clinical toxicity, management of overdose is described. The similarity of cyclobenzaprine to the tricyclic antidepressant class is emphasized; this report attempts to disseminate related information on this commonly prescribed centrally acting muscle relaxant.

  10. Rhabdomyolysis: a manifestation of cyclobenzaprine toxicity

    Science.gov (United States)

    Chabria, Shiven B

    2006-01-01

    A case of cyclobenzaprine (flexeril) overdose and the resultant rhabdomyolysis is presented. A review of the range of clinical toxicity, management of overdose is described. The similarity of cyclobenzaprine to the tricyclic antidepressant class is emphasized; this report attempts to disseminate related information on this commonly prescribed centrally acting muscle relaxant. PMID:16846511

  11. Rhabdomyolysis: a manifestation of cyclobenzaprine toxicity

    OpenAIRE

    2006-01-01

    Abstract A case of cyclobenzaprine (flexeril) overdose and the resultant rhabdomyolysis is presented. A review of the range of clinical toxicity, management of overdose is described. The similarity of cyclobenzaprine to the tricyclic antidepressant class is emphasized; this report attempts to disseminate related information on this commonly prescribed centrally acting muscle relaxant.

  12. Kentucky Department for Natural Resources and Environmental Protection permit application for air contaminant source: SRC-I demonstration plant, Newman, Kentucky. Supplement I. [Additional information on 38 items requested by KY/DNREP

    Energy Technology Data Exchange (ETDEWEB)

    Pearson, Jr., John F.

    1981-02-13

    In response to a letter from KY/DNREP, January 19, 1981, ICRC and DOE have prepared the enclosed supplement to the Kentucky Department for Natural Resources and Environmental Protection Permit Application for Air Contaminant Source for the SRC-I Demonstration Plant. Each of the 38 comments contained in the letter has been addressed in accordance with the discussions held in Frankfort on January 28, 1981, among representatives of KY/DNREP, EPA Region IV, US DOE, and ICRC. The questions raised involve requests for detailed information on the performance and reliability of proprietary equipment, back-up methods, monitoring plans for various pollutants, composition of wastes to flares, emissions estimates from particular operations, origin of baseline information, mathematical models, storage tanks, dusts, etc. (LTN)

  13. Air Quality at Your Street

    DEFF Research Database (Denmark)

    Jensen, Steen Solvang; Becker, Thomas; Ketzel, Matthias

    DTU Transport as well as data on travel speeds based on GPS data from SpeedMap from the Danish Road Directorate. Modelled concentrations have been compared to fixed regional, urban background and street air quality monitoring stations to assess uncertainties, and to model results from about 30 streets......Citizens are frequently concerned about the air quality where they live, where they go to work, where their children go to kindergarten or where they want to move to. Municipalities may also have an interest in location based air quality information e.g. in relation to screening of complaints from...... concerned citizents, or in the context of localization of institutions, etc. The purpose of the project ‘Air Quality at Your Street’ is to create interactive air quality maps on the internet using webGIS to illustrate the geographical variation of air quality in Denmark for selected health related air...

  14. Toxic Shock Syndrome (For Parents)

    Science.gov (United States)

    ... Feeding Your 1- to 2-Year-Old Toxic Shock Syndrome KidsHealth > For Parents > Toxic Shock Syndrome Print ... en español Síndrome de shock tóxico About Toxic Shock Syndrome Toxic shock syndrome (TSS) is a serious ...

  15. Human toxicity potentials for life-cycle assessment and toxics release inventory risk screening.

    Science.gov (United States)

    Hertwich, E G; Mateles, S F; Pease, W S; McKone, T E

    2001-04-01

    The human toxicity potential (HTP), a calculated index that reflects the potential harm of a unit of chemical released into the environment, is based on both the inherent toxicity of a compound and its potential dose. It is used to weight emissions inventoried as part of a life-cycle assessment (LCA) or in the toxics release inventory (TRI) and to aggregate emissions in terms of a reference compound. Total emissions can be evaluated in terms of benzene equivalence (carcinogens) and toluene equivalents (noncarcinogens). The potential dose is calculated using a generic fate and exposure model, CalTOX, which determines the distribution of a chemical in a model environment and accounts for a number of exposure routes, including inhalation, ingestion of produce, fish, and meat, and dermal contact with water and soil. Toxicity is represented by the cancer potency q1* for carcinogens and the safe dose (RfD, RfC) for noncarcinogens. This article presents cancer and noncancer HTP values for air and surface-water emissions of 330 compounds. This list covers 258 chemicals listed in U.S. Environmental Protection Agency TRI, or 79 weight-% of the TRI releases to air reported in 1997.

  16. Medical Devices, Supporting Networks, and their Vulnerabilities: A Case Study Of the Integration of Medical Networks into the Air Force Information Network

    Science.gov (United States)

    2005-03-01

    security, and information classification. New technologies such as WIFI , cell phones, and Blackberries introduce new vulnerabilities not seen before...means of evading armed security guards. For a cyber terrorist, the same devastating result could be achieved by hacking into the control network

  17. Trace Contaminant Monitor for Air in Spacecraft Project

    Data.gov (United States)

    National Aeronautics and Space Administration — A need exists for analyzers that can measure trace contaminants in air on board spacecraft. Toxic gas buildup can endanger the crew particularly during long...

  18. Psychostimulant toxicity in children

    Directory of Open Access Journals (Sweden)

    Ozalp Ekinci

    2013-04-01

    Full Text Available Methylphenidate is used for the treatment of attention deficit hyperactivity disorder in children above the age of 6 with a high safety and tolerability. When used above the recommended dosage, methylphenidate has been reported to cause toxicity symptoms including neuro-psychiatric and cardiac adverse reactions. In this overview paper, the available literature on psyhcostimulant toxicity in children and the clinical symptoms and follow-up of a 4-year-old child who accidentally used high dose of methylphenidate will be discussed. [Archives Medical Review Journal 2013; 22(2.000: 184-193

  19. Toxic and Metabolic Myelopathies.

    Science.gov (United States)

    Ramalho, Joana; Nunes, Renato Hoffmann; da Rocha, Antonio José; Castillo, Mauricio

    2016-10-01

    Myelopathy describes any neurologic deficit related to the spinal cord. It is most commonly caused by its compression by neoplasms, degenerative disc disease, trauma, or infection. Less common causes of myelopathy include spinal cord tumors, infection, inflammatory, neurodegenerative, vascular, toxic, and metabolic disorders. Conditions affecting the spinal cord must be recognized as early as possible to prevent progression that may lead to permanent disability. Biopsy is rarely performed, thus the diagnosis and management rely on patient׳s history, physical examination, laboratory results, and imaging findings. Here we review the clinical presentations, pathophysiological mechanisms, and magnetic resonance imaging findings of myelopathies related to metabolic or toxic etiologies.

  20. The toxicity of refrigerants

    Energy Technology Data Exchange (ETDEWEB)

    Calm, J.M.

    1996-07-01

    This paper presents toxicity data and exposure limits for refrigerants. The data address both acute (short-term, single exposure) and chronic (long-term, repeated exposure) effects, with emphasis on the former. The refrigerants covered include those in common use for the last decade, those used as components in alternatives, and selected candidates for future replacements. The paper also reviews the toxicity indicators used in both safety standards and building, mechanical, and fire codes. It then outlines current classification methods for refrigerant safety and relates them to standard and code usage.

  1. Yellow phosphorus process to convert toxic chemicals to non-toxic products

    Science.gov (United States)

    Chang, S.G.

    1994-07-26

    The present invention relates to a process for generating reactive species for destroying toxic chemicals. This process first contacts air or oxygen with aqueous emulsions of molten yellow phosphorus. This contact results in rapid production of abundant reactive species such as O, O[sub 3], PO, PO[sub 2], etc. A gaseous or liquid aqueous solution organic or inorganic chemicals is next contacted by these reactive species to reduce the concentration of toxic chemical and result in a non-toxic product. The final oxidation product of yellow phosphorus is phosphoric acid of a quality which can be recovered for commercial use. A process is developed such that the byproduct, phosphoric acid, is obtained without contamination of toxic species in liquids treated. A gas stream containing ozone without contamination of phosphorus containing species is also obtained in a simple and cost-effective manner. This process is demonstrated to be effective for destroying many types of toxic organic, or inorganic, compounds, including polychlorinated biphenyls (PCB), aromatic chlorides, amines, alcohols, acids, nitro aromatics, aliphatic chlorides, polynuclear aromatic compounds (PAH), dyes, pesticides, sulfides, hydroxyamines, ureas, dithionates and the like. 20 figs.

  2. [Peers contribution to mental health work: considerations on the relationship between formal and informal help. A case study in a mental health facility in Buenos Aires].

    Science.gov (United States)

    Ardila Gómez, Sara; Agrest, Martín; Abadi, Daniel; Cáceres, Carmen

    2013-01-01

    Including peers to the mental health workforce has been part of a larger debate regarding specificity and incumbencies of peers' work, as well as their relationship with other workers. While some members of the workforce are proposing to train peers to have them help in different settings and interventions, others see them as unfair and underprepared competitors trying to replace them. Based on this debate, and from a Collective Health perspective on the concept of "care", this paper supports the idea that, since they put "care" as central to anything done by the mental health workforce, peers could be crucial to practices in Mental Health. An experience that took place in a Day Hospital in Buenos Aires City, conversed within a group dedicated to reflect on peers' support, is analyzed in order to unveil the relationship between peers and professionals, as well as peers' specificity. It is withstand that one of the main contributions of including peers is to help professionals think more about the relational dimension of their work and about the way they treat, call and refer to patients.

  3. Culture of primary ciliary dyskinesia epithelial cells at air-liquid interface can alter ciliary phenotype but remains a robust and informative diagnostic aid.

    Directory of Open Access Journals (Sweden)

    Robert A Hirst

    Full Text Available BACKGROUND: The diagnosis of primary ciliary dyskinesia (PCD requires the analysis of ciliary function and ultrastructure. Diagnosis can be complicated by secondary effects on cilia such as damage during sampling, local inflammation or recent infection. To differentiate primary from secondary abnormalities, re-analysis of cilia following culture and re-differentiation of epithelial cells at an air-liquid interface (ALI aids the diagnosis of PCD. However changes in ciliary beat pattern of cilia following epithelial cell culture has previously been described, which has brought the robustness of this method into question. This is the first systematic study to evaluate ALI culture as an aid to diagnosis of PCD in the light of these concerns. METHODS: We retrospectively studied changes associated with ALI-culture in 158 subjects referred for diagnostic testing at two PCD centres. Ciliated nasal epithelium (PCD n = 54; non-PCD n  111 was analysed by high-speed digital video microscopy and transmission electron microscopy before and after culture. RESULTS: Ciliary function was abnormal before and after culture in all subjects with PCD; 21 PCD subjects had a combination of static and uncoordinated twitching cilia, which became completely static following culture, a further 9 demonstrated a decreased ciliary beat frequency after culture. In subjects without PCD, secondary ciliary dyskinesia was reduced. CONCLUSIONS: The change to ciliary phenotype in PCD samples following cell culture does not affect the diagnosis, and in certain cases can assist the ability to identify PCD cilia.

  4. Interspecies quantitative structure-toxicity-toxicity (QSTTR) relationship modeling of ionic liquids. Toxicity of ionic liquids to V. fischeri, D. magna and S. vacuolatus.

    Science.gov (United States)

    Das, Rudra Narayan; Roy, Kunal; Popelier, Paul L A

    2015-12-01

    Considering the increasing uses of ionic liquids (ILs) in various industrial processes and chemical engineering operations, a complete assessment of their hazardous profile is essential. In the absence of adequate experimental data, in silico modeling might be helpful in filling data gaps for the toxicity of ILs towards various ecological indicator organisms. Using the rationale of taxonomic relatedness, the development of predictive quantitative structure-toxicity-toxicity relationship (QSTTR) models allows predicting the toxicity of ILs to a particular species using available experimental toxicity data towards a different species. Such studies may employ, along with the available experimental toxicity data to a species, molecular structure features and physicochemical properties of chemicals as independent variables for prediction of the toxicity profile against another closely related species. A few such interspecies toxicity correlation models have been reported in the literature for diverse chemicals in general, but this approach has been rarely applied to the class of ionic liquids. The present study involves the use of IL toxicity data towards the bacteria Vibrio fischeri along with molecular structure derived information or computational descriptors like extended topochemical atom (ETA) indices, quantum topological molecular similarity (QTMS) descriptors and computed lipophilicity measure (logk0) for the interspecies exploration of the toxicity data towards green algae S. vacuolatus and crustacea Daphnia magna, separately. This modeling study has been performed in accordance with the OECD guidelines. Finally, predictions for a true external set have been performed to fill the data gap of toxicity towards daphnids and algae using the Vibrio toxicity data and molecular structure attributes.

  5. Toxic Substances Portal- Arsenic

    Science.gov (United States)

    ... a naturally occurring element widely distributed in the earth's crust. In the environment, arsenic is combined with ... workplace air (10 µg/m 3 ) for 8 hour shifts and 40 hour work weeks. top References ...

  6. Toxic Test Chambers

    Data.gov (United States)

    Federal Laboratory Consortium — Description/History: Hazardous material test facility Both facilities have 16,000 cubic foot chambers, equipped with 5000 CFM CBR filter systems with an air change...

  7. Toxicity of Military Unique Compounds in Aquatic Organisms: An Annotated Bibliography (Studies Published Through 1996)

    Science.gov (United States)

    1998-04-01

    Biochemistry/Air Pollution/Soil Pollutants/Water. Haley, M. V., Checkai, R. T., Kurnas , C. W., and Wentsel, R. S. Toxicity Determination of Explosive...Membranes/Metals/Operations/Residues/Sites/Soil Surveys/ Toxicity/Water/Hazardous Materials/Contamination/Explosives/ Response. Haley, M. V., and Kurnas ... Kurnas , C. W., Chester, N. A., and Muse, W. T. Aquatic Toxicity of the Decontamination Agent: Multipurpose (DAM) Decontamination Solution. Giveth

  8. 40 CFR Table 2 to Subpart Hhh of... - Toxic Equivalency Factors

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Toxic Equivalency Factors 2 Table 2 to Subpart HHH of Part 62 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS..., Subpt. HHH, Table 2 Table 2 to Subpart HHH of Part 62—Toxic Equivalency Factors Dioxin/furan...

  9. 2004 Toxic Release Inventory Sites in Louisiana, Geographic NAD83, EPA (2006) [toxic_release_inventory_site_LA_EPA_2004

    Data.gov (United States)

    Louisiana Geographic Information Center — Data extracted from the EPA Toxics Release Inventory (TRI) system for reporting year 2004. The dataset contains facility identification, submitted and/or preferred...

  10. Respiratory Toxicity Biomarkers

    Science.gov (United States)

    The advancement in high throughput genomic, proteomic and metabolomic techniques have accelerated pace of lung biomarker discovery. A recent growth in the discovery of new lung toxicity/disease biomarkers have led to significant advances in our understanding of pathological proce...

  11. Nanomaterials and Retinal Toxicity

    Science.gov (United States)

    The neuroretina should be considered as a potential site of nanomaterial toxicity. Engineered nanomaterials may reach the retina through three potential routes of exposure including; intra­ vitreal injection of therapeutics; blood-borne delivery in the retinal vasculature an...

  12. Air Pollution

    Science.gov (United States)

    ... to view this content or go to source URL . What NIEHS is Doing on Air Pollution Who ... Junction Last Reviewed: February 06, 2017 This page URL: NIEHS website: https://www.niehs.nih.gov/ Email ...

  13. Comparative Toxicity of Gasoline and Diesel Engine Emissions

    Energy Technology Data Exchange (ETDEWEB)

    JeanClare Seagrave; Joe L. Mauderly; Barbara Zielinska; John Sagebiel; Kevin Whitney; Doughlas R. Lawson; Michael Gurevich

    2000-06-19

    Better information on the comparative toxicity of airborne emissions from different types of engines is needed to guide the development of heavy vehicle engine, fuel, lubricant, and exhaust after-treatment technologies, and to place the health hazards of current heavy vehicle emissions in their proper perspective. To help fill this information gap, samples of vehicle exhaust particles and semi-volatile organic compounds (SVOC) were collected and analyzed. The biological activity of the combined particle-SVOC samples is being tested using standardized toxicity assays. This report provides an update on the design of experiments to test the relative toxicity of engine emissions from various sources.

  14. Mobile air quality studies (MAQS in inner cities: particulate matter PM10 levels related to different vehicle driving modes and integration of data into a geographical information program

    Directory of Open Access Journals (Sweden)

    Uibel Stefanie

    2012-10-01

    Full Text Available Abstract Background Particulate matter (PM is assumed to exert a major burden on public health. Most studies that address levels of PM use stationary measure systems. By contrast, only few studies measure PM concentrations under mobile conditions to analyze individual exposure situations. Methods By combining spatial-temporal analysis with a novel vehicle-mounted sensor system, the present Mobile Air Quality Study (MAQS aimed to analyse effects of different driving conditions in a convertible vehicle. PM10 was continuously monitored in a convertible car, driven with roof open, roof closed, but windows open, or windows closed. Results PM10 values inside the car were nearly always higher with open roof than with roof and windows closed, whereas no difference was seen with open or closed windows. During the day PM10 values varied with high values before noon, and occasional high median values or standard deviation values due to individual factors. Vehicle speed in itself did not influence the mean value of PM10; however, at traffic speed (10 – 50 km/h the standard deviation was large. No systematic difference was seen between PM10 values in stationary and mobile cars, nor was any PM10 difference observed between driving within or outside an environmental (low emission zone. Conclusions The present study has shown the feasibility of mobile PM analysis in vehicles. Individual exposure of the occupants varies depending on factors like time of day as well as ventilation of the car; other specific factors are clearly identifiably and may relate to specific PM10 sources. This system may be used to monitor individual exposure ranges and provide recommendations for preventive measurements. Although differences in PM10 levels were found under certain ventilation conditions, these differences are likely not of concern for the safety and health of passengers.

  15. Cadmium potentiates toxicity of cypermethrin in zebrafish.

    Science.gov (United States)

    Yang, Ye; Ye, Xiaoqing; He, Buyuan; Liu, Jing

    2016-02-01

    Co-occurrence of pesticides such as synthetic pyrethroids and metals in aquatic ecosystems raises concerns over their combined ecological effects. Cypermethrin, 1 of the top 5 synthetic pyrethroids in use, has been extensively detected in surface water. Cadmium (Cd) has been recognized as 1 of the most toxic metals and is a common contaminant in the aquatic system. However, little information is available regarding their joint toxicity. In the present study, combined toxicity of cypermethrin and Cd and the underlying mechanisms were investigated. Zebrafish embryos and adults were exposed to the individual contaminant or binary mixtures. Co-exposure to cypermethrin and Cd produced synergistic effects on the occurrence of crooked body, pericardial edema, and noninflation of swim bladder. The addition of Cd significantly potentiated cypermethrin-induced spasms and caused more oxidative stress in zebrafish larvae. Cypermethrin-mediated induction of transcription levels and catalytic activities of cytochrome P450 (CYP) enzyme were significantly down-regulated by Cd in both zebrafish larvae and adults. Chemical analytical data showed that in vitro elimination of cypermethrin by CYP1A1 was inhibited by Cd. The addition of Cd caused an elevation of in vivo cypermethrin residue levels in the mixture-exposed adult zebrafish. These results suggest that the enhanced toxicity of cypermethrin in the presence of Cd results from the inhibitory effects of Cd on CYP-mediated biotransformation of this pesticide. The authors' findings provide a deeper understanding of the mechanistic basis accounting for the joint toxicity of cypermethrin and Cd.

  16. 贫信息下空袭兵器威胁能力评估方法%Research on Assessment for Threat Ability of Air Raid Weapon under Lacking Information

    Institute of Scientific and Technical Information of China (English)

    赵喜; 李修和; 沈阳

    2011-01-01

    Nowadays, at aerial defense combat, the air raid weapons become more and more powerful,which bring more menace to our key target. So it is badly needed to evaluate the menace ability of air raid weapons, so as to assign aerial defense power and protect our target. This paper researches the process of assessment for threat ability of aerial raid weapon, provides the arithmetic and math model under the background of modern aerial-defense combat and lacking information. The example given in the end shows the practicability of the model.%现代防空作战中,各种空袭兵器突袭能力不断增强,对我方目标构成了极大威胁.因此,需要对空袭兵器的威胁能力进行评估,合理分配各种防空火力,以达到保护我方目标的目的.研究了现代防空作战背景下,空袭兵器威胁能力评估的全过程,给出了贫信息下,威胁能力评估的算法,建立了数学模型,最后用实例说明了该评估方法的实用性.

  17. Toxic hazards of underground excavation

    Energy Technology Data Exchange (ETDEWEB)

    Smith, R.; Chitnis, V.; Damasian, M.; Lemm, M.; Popplesdorf, N.; Ryan, T.; Saban, C.; Cohen, J.; Smith, C.; Ciminesi, F.

    1982-09-01

    Inadvertent intrusion into natural or man-made toxic or hazardous material deposits as a consequence of activities such as mining, excavation or tunnelling has resulted in numerous deaths and injuries in this country. This study is a preliminary investigation to identify and document instances of such fatal or injurious intrusion. An objective is to provide useful insights and information related to potential hazards due to future intrusion into underground radioactive-waste-disposal facilities. The methodology used in this study includes literature review and correspondence with appropriate government agencies and organizations. Key categories of intrusion hazards are asphyxiation, methane, hydrogen sulfide, silica and asbestos, naturally occurring radionuclides, and various mine or waste dump related hazards.

  18. Off-air treatment in waste treatment systems and landfills - consequences for practical operation. 62. information meeting of ANS e.V.; Abluftbehandlung bei MBA und Deponiebetrieb - Konsequenzen fuer die Praxis. 62. Informationsgespraech des ANS e.V.

    Energy Technology Data Exchange (ETDEWEB)

    Fricke, K.; Burth, M.; Dichtl, N.; Wallmann, R. (eds.)

    2001-07-01

    The new German Landfill Ordinance of 1 March 2001 specifies the requirements on construction and operation of mechanical-biological waste treatment plants and landfills as well as the continued operation of existing landfills. The conference provided current information of R + D projects as well as practical experience in Austria and Germany, with particular regard to the issues of off-air emissions and landfilling. [German] Seit dem 1. Maerz 2001 ist die Artikelverordnung rechtswirksam. Sie enthaelt Anforderungen an den Bau und Betrieb von mechanisch-biologischen Restabfallbehandlungsanlagen und Deponien. Die Abfallablagerungsverordnung hat darueber hinaus weitreichende Konsequenzen fuer die Betriebsdauer bestehender Deponien. Ziel der Tagung ist es, aktuelle Informationen aus laufenden Forschungs- und Entwicklungsvorhaben sowie Erfahrungen bei der praktischen Umsetzung zu praesentieren, die insbesondere zu den Themenkomplexen Abluftemissionen und Deponierung zur Zeit in Oesterreich und Deutschland vorliegen. (orig.)

  19. Air cleaning using regenerative silica gel wheel

    DEFF Research Database (Denmark)

    Fang, Lei

    2011-01-01

    This paper discussed the necessity of indoor air cleaning and the state of the art information on gas-phase air cleaning technology. The performance and problems of oxidation and sorption air cleaning technology were summarized and analysed based on the literature studies. Eventually, based on an...

  20. An operational system for the assimilation of the satellite information on wild-land fires for the needs of air quality modelling and forecasting

    Directory of Open Access Journals (Sweden)

    M. Sofiev

    2009-09-01

    Full Text Available This paper investigates a potential of two remotely sensed wild-land fire characteristics: 4-μm Brightness Temperature Anomaly (TA and Fire Radiative Power (FRP for the needs of operational chemical transport modelling and short-term forecasting of atmospheric composition and air quality. The treatments of the TA and FRP data are presented and a methodology for evaluating the emission fluxes of primary aerosols (PM2.5 and total PM is described. The method does not include the complicated analysis of vegetation state, fuel load, burning efficiency and related factors, which are uncertain but inevitably involved in approaches based on burnt-area scars or similar products. The core of the current methodology is based on the empirical emission factors that are used to convert the observed temperature anomalies and fire radiative powers into emission fluxes. These factors have been derived from the analysis of several fire episodes in Europe (28.4–5.5.2006, 15.8–25.8.2006 and in August 2008. These episodes were characterised by: (i well-identified FRP and TA values, and (ii available ground-based observations of aerosol concentrations, and optical thickness for the regions where the contribution of the fire smoke to the concentrations of PM2.5 was dominant, in comparison with those of other pollution sources. The emission factors were determined separately for the forested and grassland areas; in case of mixed-type land use, an intermediate scaling was assumed. Despite significant differences between the TA and FRP methodologies, an accurate non-linear fitting was found between the predictions of these approaches. The agreement was comparatively weak only for small fires, for which the accuracy of both products is expected to be low. The applications of the Fire Assimilation System (FAS in combination with the dispersion model SILAM showed that both the TA and FRP products are suitable for the evaluation of the emission

  1. INEEL AIR MODELING PROTOCOL ext

    Energy Technology Data Exchange (ETDEWEB)

    C. S. Staley; M. L. Abbott; P. D. Ritter

    2004-12-01

    Various laws stemming from the Clean Air Act of 1970 and the Clean Air Act amendments of 1990 require air emissions modeling. Modeling is used to ensure that air emissions from new projects and from modifications to existing facilities do not exceed certain standards. For radionuclides, any new airborne release must be modeled to show that downwind receptors do not receive exposures exceeding the dose limits and to determine the requirements for emissions monitoring. For criteria and toxic pollutants, emissions usually must first exceed threshold values before modeling of downwind concentrations is required. This document was prepared to provide guidance for performing environmental compliance-driven air modeling of emissions from Idaho National Engineering and Environmental Laboratory facilities. This document assumes that the user has experience in air modeling and dose and risk assessment. It is not intended to be a "cookbook," nor should all recommendations herein be construed as requirements. However, there are certain procedures that are required by law, and these are pointed out. It is also important to understand that air emissions modeling is a constantly evolving process. This document should, therefore, be reviewed periodically and revised as needed. The document is divided into two parts. Part A is the protocol for radiological assessments, and Part B is for nonradiological assessments. This document is an update of and supersedes document INEEL/INT-98-00236, Rev. 0, INEEL Air Modeling Protocol. This updated document incorporates changes in some of the rules, procedures, and air modeling codes that have occurred since the protocol was first published in 1998.

  2. Wagging ETOM's Long Tail: MOOCs, Hangouts on Air, and Formal and Informal Undergraduate Experiences with Climate Change Science and Clean Energy Solutions

    Science.gov (United States)

    Haines-Stiles, G.; Alley, R. B.; Akuginow, E.; McNeal, K.; Blockstein, D.

    2014-12-01

    Climate change can reasonably be described as a "wicked problem" meaning that it is complex, difficult and multi-faceted, although critical to equitable development and the sustainability of human civilization. But while the Wikipedia definition says such problems are "impossible" to solve, not even to try will lead to certain failure. "Earth: The Operators' Manual" (ETOM) was an NSF-funded informal science education project with 3 hour-long TV programs appearing on PBS in 2011 and 2012, along with live presentations by series host, Penn State's Richard Alley, and others at 5 major science centers. Uniquely among climate change programming, ETOM gave equal time to identifying solutions along with climate science, and made all its materials freely available via YouTube. Formal and informal science educators can register to download HD videos for classroom and outreach use, and signups have ranged from middle schools to 4-year colleges. Building on the success of the series and Alley's companion tradebook of the same name, Penn State working with Coursera invited Alley to develop a MOOC entitled "Energy, The Environment and Our Future" that similarly combined the essential science along with clean energy solutions. The course reached more than 30,000 students in the first semester of 2014. More recently the ETOM team has partnered with the National Council for Science and the Environment (NCSE) to develop "READ for the EARTH," an NSF EAGER project, offering campuses the opportunity to adopt Alley's book, the ETOM videos (including "How To Talk To An Ostrich"), NCSE's www.CAMELclimatechange.org web site and other resources for both formal and informal uses. Some campuses have used the book with honors classes, and some are exploring adapting ETOM as a first year reading experience for all freshman. Our presentation will share reactions to the MOOC, to the pilot phases of "READ for the EARTH" and present both qualitative and quantitative results. Some of the most

  3. 工作场所空气中6种有毒物质的填充柱气相色谱测定法%Simultaneous determination of 6 kinds toxic substances in the air of workplace by packed column gas chromatography

    Institute of Scientific and Technical Information of China (English)

    黄奕涛; 房树超

    2013-01-01

    [Objective] To study and establish a method for simultaneous determination of n- hexane, acetone, methyl ethyl ketone, benzene, toluene, xylene in the air of workplace by packed column gas chromatography. [Methods] Samples were collected by using active carbon tubes, desorbed with carbon bisulfide, separated with constant temperature packed column and detected using FID detector. [Results] Under the established experiment conditions, the 6 kinds of toxic substances were well separated by packed column. The correlative coefficient r was above 0.999. The labeled recovery was from 86.4% to 95.2%. [ Conclusion] This method can effectively separate and accurately determine n- hexane, acetone, methyl ethyl ketone, benzene, toluene, xylene in the air of workplace. Moreover, this method has a simple operation and cheap equipment, and it is especially suitable for laboratory at the grass-roots level.%目的 建立同时测定工作场所空气中正己烷、丙酮、丁酮、苯、甲苯、二甲苯等6种有毒物质的填充物气相色谱法.方法 采用活性炭管吸附采集样品,经二硫化碳解吸后进样,恒温法,填充柱分离,FID检测器气相色谱法检测.结果 在建立的实验条件下,6种待测物质在填充柱上分离良好,工作曲线的相关系数r值在0.999以上,加标回收率在86.4% ~95.2%之间.结论 该方法能有效分离和准确测定工作场所空气中正己烷、丙酮、丁酮、苯、甲苯、二甲苯等6种有毒物质,且操作简单,所需仪器设备便宜,尤其适用于基层实验室.

  4. Predictive Modeling of Developmental Toxicity

    Science.gov (United States)

    The use of alternative methods in conjunction with traditional in vivo developmental toxicity testing has the potential to (1) reduce cost and increase throughput of testing the chemical universe, (2) prioritize chemicals for further targeted toxicity testing and risk assessment,...

  5. Mercury Information Clearinghouse

    Energy Technology Data Exchange (ETDEWEB)

    Chad A. Wocken; Michael J. Holmes; Dennis L. Laudal; Debra F. Pflughoeft-Hassett; Greg F. Weber; Nicholas V. C. Ralston; Stanley J. Miller; Grant E. Dunham; Edwin S. Olson; Laura J. Raymond; John H. Pavlish; Everett A. Sondreal; Steven A. Benson

    2006-03-31

    The Canadian Electricity Association (CEA) identified a need and contracted the Energy & Environmental Research Center (EERC) to create and maintain an information clearinghouse on global research and development activities related to mercury emissions from coal-fired electric utilities. With the support of CEA, the Center for Air Toxic Metals{reg_sign} (CATM{reg_sign}) Affiliates, and the U.S. Department of Energy (DOE), the EERC developed comprehensive quarterly information updates that provide a detailed assessment of developments in the various areas of mercury monitoring, control, policy, and research. A total of eight topical reports were completed and are summarized and updated in this final CEA quarterly report. The original quarterly reports can be viewed at the CEA Web site (www.ceamercuryprogram.ca). In addition to a comprehensive update of previous mercury-related topics, a review of results from the CEA Mercury Program is provided. Members of Canada's coal-fired electricity generation sector (ATCO Power, EPCOR, Manitoba Hydro, New Brunswick Power, Nova Scotia Power Inc., Ontario Power Generation, SaskPower, and TransAlta) and CEA, have compiled an extensive database of information from stack-, coal-, and ash-sampling activities. Data from this effort are also available at the CEA Web site and have provided critical information for establishing and reviewing a mercury standard for Canada that is protective of environment and public health and is cost-effective. Specific goals outlined for the CEA mercury program included the following: (1) Improve emission inventories and develop management options through an intensive 2-year coal-, ash-, and stack-sampling program; (2) Promote effective stack testing through the development of guidance material and the support of on-site training on the Ontario Hydro method for employees, government representatives, and contractors on an as-needed basis; (3) Strengthen laboratory analytical capabilities through

  6. Separations chemistry of toxic metals

    Energy Technology Data Exchange (ETDEWEB)

    Smith, P.; Barr, M.; Barrans, R. [and others

    1996-04-01

    Sequestering and removing toxic metal ions from their surroundings is an increasingly active area of research and is gaining importance in light of current environmental contamination problems both within the DOE complex and externally. One method of separating metal ions is to complex them to a molecule (a ligand or chelator) which exhibits specific binding affinity for a toxic metal, even in the presence of other more benign metals. This approach makes use of the sometimes subtle differences between toxic and non-toxic metals resulting from variations in size, charge and shape. For example, toxic metals such as chromium, arsenic, and technetium exist in the environment as oxyanions, negatively charged species with a characteristic tetrahedral shape. Other toxic metals such as actinides and heavy metals are positively charged spheres with specific affinities for particular donor atoms such as oxygen (for actinides) and nitrogen (for heavy metals). In most cases the toxic metals are found in the presence of much larger quantities of less toxic metals such as sodium, calcium and iron. The selectivity of the chelators is critical to the goal of removing the toxic metals from their less toxic counterparts. The approach was to build a ligand framework that complements the unique characteristics of the toxic metal (size, charge and shape) while minimizing interactions with non-toxic metals. The authors have designed ligands exhibiting specificity for the target metals; they have synthesized, characterized and tested these ligands; and they have shown that they exhibit the proposed selectivity and cooperative binding effects.

  7. 基于区间数的空中进攻作战信息流转模式构建%Information flowing pattern construction for air offensive campaign based on interval number

    Institute of Scientific and Technical Information of China (English)

    杨迎辉; 李建华; 丁未; 南明莉

    2014-01-01

    An efficient and reasonable information flowing pattern is the precondition and important guaran-tee for effective implementation of an air offensive campaign (AOC).To construct an information flowing pat-tern for AOC,basic definitions of the information flowing pattern are given based on the complex network theo-ry,and the information flowing relationships between intelligence security,operational command and weapon control in the three stages of AOC are analyzed.By introducing the concept and operation rules of the interval number,and taking information flow,information quality and transmission time as optimization targets,the multi-objective programming model of the information flowing pattern for AOC based on the interval number is constructed.Combined with methods of linear weight and interval number satisfaction,the model is translated into a two-level nesting optimization problem of signal-objective with a certain type,and the differential evolve-ment algorithm is chosen to solve it.Finally,the rationality and feasibility of the model and method are verified through a specific example.%高效合理的信息流转模式是有效实施空中进攻作战的前提和重要保障。针对空中进攻作战信息流转模式构建问题,给出了基于复杂网络理论的信息流转模式基本定义,解析了空中进攻作战3个阶段的情报保障、作战指挥和武器控制信息的流转关系。引入区间数概念及运算规则,以信息流量、信息质量和传输时间为优化目标,构建了基于区间数的空中进攻作战信息流转模式多目标规划模型,结合线性加权法和区间数满意度,将其划归为单目标确定型两层嵌套优化模型,并利用微分进化算法进行求解。最后结合实例,验证了该模型与方法的合理性与可行性。

  8. Nanoparticle toxicity and cancer

    Science.gov (United States)

    Prevenslik, T.

    2011-07-01

    Nanoparticles (NPs) have provided significant advancements in cancer treatment. But as in any technology, there is a darkside. Experiments have shown NPs in body fluids pose a health risk by causing DNA damage that in of itself may lead to cancer. To avoid the dilemma that NPs are toxic to both cancer cells and DNA alike, the mechanism of NP toxicity must be understood so that the safe use of NPs may go forward. Reactive oxidative species (ROS) of peroxide and hydroxyl radicals damage the DNA by chemical reaction, but require NPs provide energies of about 5 eV not possible by surface effects. Only electromagnetic (EM) radiations beyond ultraviolet (UV) levels may explain the toxicity of NPs. Indeed, experiments show DNA damage from radiation, Hence, it is reasonable to hypothesize that NPs produce their own source of UV radiation, albeit at low intensity. Ionizing radiation from NPs at UV levels is consistent with the theory of QED induced EM radiation. QED stands for quantum electrodynamics. By this theory, fine radiation need not be limited to natural or man-made NPs. Extensions suggest UV radiation is produced from biological NPs within the body, e.g., enzyme induced fragmentation of epithelial tissue, exocytosis of small proteins, and ironically, the same molecular markers used to detect cancer itself.

  9. The toxicity of methanol

    Energy Technology Data Exchange (ETDEWEB)

    Tephly, T.R. (Univ. of Iowa, Iowa City (USA))

    1991-01-01

    Methanol toxicity in humans and monkeys is characterized by a latent period of many hours followed by a metabolic acidosis and ocular toxicity. This is not observed in most lower animals. The metabolic acidosis and blindness is apparently due to formic acid accumulation in humans and monkeys, a feature not seen in lower animals. The accumulation of formate is due to a deficiency in formate metabolism which is, in turn, related, in part, to low hepatic tetrahydrofolate (H{sub 4}folate). An excellent correlation between hepatic H{sub 4} folate and formate oxidation rates has been shown within and across species. Thus, humans and monkeys possess low hepatic H{sub 4}folate levels, low rates of formate oxidation and accumulation of formate after methanol. Formate, itself, produces blindness in monkeys in the absence of metabolic acidosis. In addition to low hepatic H{sub 4}folate concentrations, monkeys and humans also have low hepatic 10-formyl H{sub 4}folate dehydrogenase levels, the enzyme which is the ultimate catalyst for conversion of formate to carbon dioxide. This review presents the basis for the role of folic acid-dependent reactions in the regulation of methanol toxicity.

  10. Inclusion of functional information from perfusion SPECT improves predictive value of dose-volume parameters in lung toxicity outcome after radiotherapy for non-small cell lung cancer: A prospective study

    DEFF Research Database (Denmark)

    Farr, Katherina P; Kallehauge, Jesper F; Møller, Ditte S;

    2015-01-01

    BACKGROUND AND PURPOSE: To compare functional and standard dose-volume parameters as predictors of postradiation pulmonary toxicity in lung cancer patients undergoing curative chemo-radiotherapy (RT) studied prospectively. MATERIAL AND METHODS: A total of 58 patients treated with Intensity...... pneumonitis (RP) grade 2-5. RESULTS: Functional mean lung dose (MLD) and lung volumes receiving 5, 10, 20 and 30Gy (V5-V30, respectively) revealed high correlation with corresponding standard parameters (r>0.8). Standard MLD, V20 and V30 were significantly higher in patients with RP (p=0.01). All functional...... Modulated RT (60-66Gy) were analysed. Standard dose-volume parameters were extracted from treatment planning computed tomography (CT) scans. Corresponding functional dose-volume parameters were calculated from perfusion single-photon emission computed tomography (SPECT). Primary end-point was radiation...

  11. Air surveillance

    Energy Technology Data Exchange (ETDEWEB)

    Patton, G.W.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report summarizes the air surveillance and monitoring programs currently in operation at that Hanford Site. Atmospheric releases of pollutants from Hanford to the surrounding region are a potential source of human exposure. For that reason, both radioactive and nonradioactive materials in air are monitored at a number of locations. The influence of Hanford emissions on local radionuclide concentrations was evaluated by comparing concentrations measured at distant locations within the region to concentrations measured at the Site perimeter. This section discusses sample collection, analytical methods, and the results of the Hanford air surveillance program. A complete listing of all analytical results summarized in this section is reported separately by Bisping (1995).

  12. Foliage Plants for Improving Indoor Air Quality

    Science.gov (United States)

    Wolverton, B. C.

    1988-01-01

    NASA's research with foliage houseplants during the past 10 years has produced a new concept in indoor air quality improvement. This new and exciting technology is quite simple. Both plant leaves and roots are utilized in removing trace levels of toxic vapors from inside tightly sealed buildings. Low levels of chemicals such as carbon monoxide and formaldehyde can be removed from indoor environments by plant leaves alone, while higher concentrations of numerous toxic chemicals can be removed by filtering indoor air through the plant roots surrounded by activated carbon. The activated carbon absorbs large quantities of the toxic chemicals and retains them until the plant roots and associated microorganisms degrade and assimilate these chemicals.

  13. Modeling toxic compounds from nitric oxide emission measurements

    Science.gov (United States)

    Vallero, Daniel A.; Peirce, Jeffrey; Cho, Ki Don

    Determining the amount and rate of degradation of toxic pollutants in soil and groundwater is difficult and often requires invasive techniques, such as deploying extensive monitoring well networks. Even with these networks, degradation rates across entire systems cannot readily be extrapolated from the samples. When organic compounds are degraded by microbes, especially nitrifying bacteria, oxides or nitrogen (NO x) are released to the atmosphere. Thus, the flux of nitric oxide (NO) from the soil to the lower troposphere can be used to predict the rate at which organic compounds are degraded. By characterizing and applying biogenic and anthropogenic processes in soils the rates of degradation of organic compounds. Toluene was selected as a representative of toxic aromatic compounds, since it is inherently toxic, it is a substituted benzene compound and is listed as a hazardous air pollutant under Section 12 of the Clean Air Act Amendments of 1990. Measured toluene concentrations in soil, microbial population growth and NO fluxes in chamber studies were used to develop and parameterize a numerical model based on carbon and nitrogen cycling. These measurements, in turn, were used as indicators of bioremediation of air toxic (i.e. toluene) concentrations. The model found that chemical concentration, soil microbial abundance, and NO production can be directly related to the experimental results (significant at P hydrocarbons and oxides of nitrogen. As such, the model may be a tool for decision makers in ozone non-attainment areas.

  14. The toxicity of pay for performance.

    Science.gov (United States)

    Berwick, D M

    1995-01-01

    Despite their superficial logic, systems of merit pay or pay for performance have features that are toxic to systemic improvement. Contingent rewards doled out by supervisors cause decreased focus on customer needs, loss of accurate information about defects and improvement opportunities, avoidance of stretch goals, and decreased innovation. They may also erode teamwork. Pay for performance may mark a naive understanding of the complexity of human motivation.

  15. Air Force Research Laboratory Technology Milestones 2007

    Science.gov (United States)

    2007-01-01

    Veterinary Sciences Warfighter/Weapons Systems Integration AF echnologies Information Directorate Mission Statement: The Information Directorate leads...Advanced Industrial Practices Advanced Inspection Technologies Advanced Metallics Air Mobile Systems Research Airbase Infrastructure Technologies...Air Mobility Command, and the C- 130 System Program Office-will help to raise awareness regarding these technologies. Tip tanks are fuel tanks

  16. Toxicities of oils, dispersants and dispersed oils to algae and aquatic plants: review and database value to resource sustainability

    Science.gov (United States)

    Published toxicity results are reviewed for oils, dispersants and dispersed oils and aquatic plants. The historical phytotoxicity database consists largely of results from a patchwork of research conducted after oil spills to marine waters. Toxicity information is available for ...

  17. Enabling Mobile Air Quality App Development with an AirNow API

    Science.gov (United States)

    Dye, T.; White, J. E.; Ludewig, S. A.; Dickerson, P.; Healy, A. N.; West, J. W.; Prince, L. A.

    2013-12-01

    The U.S. Environmental Protection Agency's (EPA) AirNow program works with over 130 participating state, local, and federal air quality agencies to obtain, quality control, and store real-time air quality observations and forecasts. From these data, the AirNow system generates thousands of maps and products each hour. Each day, information from AirNow is published online and in other media to assist the public in making health-based decisions related to air quality. However, an increasing number of people use mobile devices as their primary tool for obtaining information, and AirNow has responded to this trend by publishing an easy-to-use Web API that is useful for mobile app developers. This presentation will describe the various features of the AirNow application programming interface (API), including Representational State Transfer (REST)-type web services, file outputs, and RSS feeds. In addition, a web portal for the AirNow API will be shown, including documentation on use of the system, a query tool for configuring and running web services, and general information about the air quality data and forecasts available. Data published via the AirNow API includes corresponding Air Quality Index (AQI) levels for each pollutant. We will highlight examples of mobile apps that are using the AirNow API to provide location-based, real-time air quality information. Examples will include mobile apps developed for Minnesota ('Minnesota Air') and Washington, D.C. ('Clean Air Partners Air Quality'), and an app developed by EPA ('EPA AirNow').

  18. Toxicity of nightshade berries (Solanum dulcamara) in mice.

    Science.gov (United States)

    Hornfeldt, C S; Collins, J E

    1990-01-01

    Ripened nightshade berries (Solanum dulcamara) are among the most commonly reported plant ingestions in Minnesota. Because of the lack of adequate information regarding the toxic qualities of S. dulcamara berries, the ingestion of even small quantities by children is usually treated conservatively with syrup of ipecac. The toxicity of S. dulcamara berries was studied by gavaging mice with a preparation of lyophilized berries, ripened and unripened, collected at various times of the year. Mice receiving unripened fruit from early in the season had gastrointestinal tissue changes consistent with solanine toxicity. Animals dosed with unripened fruit from the latter part of the year showed behavioral signs suggestive of solanine toxicity, however gastrointestinal lesions were not observed. In no case did the ripened fruit produce behavioral or histologic toxicity. Aggressive treatment of children ingesting limited amounts of ripened S. dulcamara berries appears to be unnecessary.

  19. Electrocardiographic Manifestations of Benzodiazepine Toxicity

    Directory of Open Access Journals (Sweden)

    Nahid Kazemzadeh

    2014-11-01

    Full Text Available Background: The aim of this study was to evaluate and compare the clinical and electrocardiographic (ECG manifestations of benzodiazepines (BZs. Methods: In this retrospective study, all BZ-poisoned patients hospitalized at Loghman Hakim Hospital between September 2010 and March 2011 were evaluated. Patients’ information including age, sex, time elapsed between the ingestion and presentation, and type of the BZ used were extracted from the patients' charts and recorded. ECGs on presentation to the emergency department (ED were evaluated and parameters such as PR interval, QRS duration, corrected QT, amplitude of S wave in lead I, height of R wave and R/S ratio in the lead aVR were also measured and recorded. Results: Oxazepam, chlordiazepoxide, lorazepam, alprazolam, diazepam, and clonazepam were ingested by 9 (3%, 13 (4.4%, 29 (9.9%, 105 (35.8%, 65 (22.2%, and 72 (24.6% patients, respectively. Mean PR interval was reported to be 0.16 ± 0.03 sec and PR interval of greater than 200 msec was detected in 12 (4.5% patients. Mean QRS duration was 0.07 ± 0.01sec and QRS≥120 msec was observed in 7 (2.6% cases. Conclusion: Diazepam is the only BZ that does not cause QRS widening and oxazepam is the only one not causing PR prolongation. It can be concluded that if a patient refers with a decreased level of consciousness and accompanying signs of BZ toxicity, QRS widening in ECG rules out diazepam, whereas PR prolongation rules out oxazepam toxicity.

  20. Air Quality Modeling in Support of the Near-Road Exposures and Effects of Urban Air Pollutants Study (NEXUS)

    OpenAIRE

    Vlad Isakov; Saravanan Arunachalam; Stuart Batterman; Sarah Bereznicki; Janet Burke; Kathie Dionisio; Val Garcia; David Heist; Steve Perry; Michelle Snyder; Alan Vette

    2014-01-01

    A major challenge in traffic-related air pollution exposure studies is the lack of information regarding pollutant exposure characterization. Air quality modeling can provide spatially and temporally varying exposure estimates for examining relationships between traffic-related air pollutants and adverse health outcomes. A hybrid air quality modeling approach was used to estimate exposure to traffic-related air pollutants in support of the Near-Road Exposures and Effects of Urban Air Pollutan...

  1. Royal Danish Air Force. Air Operations Doctrine

    DEFF Research Database (Denmark)

    Nørby, Søren

    This brief examines the development of the first Danish Air Force Air Operations Doctrine, which was officially commissioned in October 1997 and remained in effect until 2010. The development of a Danish air power doctrine was heavily influenced by the work of Colonel John Warden (USAF), both...... through his book ”The Air Campaign” and his subsequent planning of the air campaign against Iraq in 1990-1991. Warden’s ideas came to Denmark and the Danish Air Force by way of Danish Air Force students attending the United States Air Force Air University in Alabama, USA. Back in Denmark, graduates from...... the Air University inspired a small number of passionate airmen, who then wrote the Danish Air Operations Doctrine. The process was supported by the Air Force Tactical Command, which found that the work dovetailed perfectly with the transformation process that the Danish Air Force was in the midst...

  2. [Toxic shock syndrome].

    Science.gov (United States)

    Tyll, T; Bílková, M; Revinová, A; Müller, M; Čurdová, M; Zlámal, M; Holub, M

    2015-10-01

    The authors present an up-to-date review of toxic shock syndrome (TSS) - a life-threatening condition where toxins of the Gram-positive bacteria Staphyloccocus aureus and Streptococcus pyogenes play a key role in the pathogenesis. The authors provide insight into the epidemiology and pathogenesis of the disease and point out the relevant patient history data and clinical signs and symptoms that may indicate progression of TSS. Last but not least, the state of the art diagnostic and therapeutic approaches to early and full blown TSS are summarized. Case reports are presented to illustrate two different etiological forms of this relatively rare nosological entity.

  3. Protection of plants against air pollutants: Role of chemical protectants

    Energy Technology Data Exchange (ETDEWEB)

    Pandey, J.; Agrawal, M. (Banaras Hindu Univ., Varanasi (India))

    1993-03-01

    The protection of plants against air pollution damage can best be achieved either by developing pollution-tolerant cultivars or by using chemical protectants. Use of chemical protectants such as pesticides, growth regulators, anti-oxidants, fertilizers, etc. is a short-term solution to reduce the risk of air pollution damage. In addition, these protectants help in understanding the mechanism of air pollution toxicity and provide a scientific basis for assessing crop losses in field conditions. 95 refs.

  4. TOXIC SUBSTANCES FROM COAL COMBUSTION

    Energy Technology Data Exchange (ETDEWEB)

    A KOLKER; AF SAROFIM; CL SENIOR; FE HUGGINS; GP HUFFMAN; I OLMEZ; J LIGHTY; JOL WENDT; JOSEPH J HELBLE; MR AMES; N YAP; R FINKELMAN; T PANAGIOTOU; W SEAMES

    1998-12-08

    The Clean Air Act Amendments of 1990 identify a number of hazardous air pollutants (HAPs) as candidates for regulation. Should regulations be imposed on HAP emissions from coal-fired power plants, a sound understanding of the fundamental principles controlling the formation and partitioning of toxic species during coal combustion will be needed. With support from the Federal Energy Technology Center (FETC), the Electric Power Research Institute, the Lignite Research Council, and VTT (Finland), Physical Sciences Inc. (PSI) has teamed with researchers from USGS, MIT, the University of Arizona (UA), the University of Kentucky (UK), the University of Connecticut (UC), the University of Utah (UU) and the University of North Dakota Energy and Environmental Research Center (EERC) to develop a broadly applicable emissions model useful to regulators and utility planners. The new Toxics Partitioning Engineering Model (ToPEM) will be applicable to all combustion conditions including new fuels and coal blends, low-NO combustion systems, and new power generation x plants. Development of ToPEM will be based on PSI's existing Engineering Model for Ash Formation (EMAF). This report covers the reporting period from 1 July 1998 through 30 September 1998. During this period distribution of all three Phase II coals was completed. Standard analyses for the whole coal samples were also completed. Mössbauer analysis of all project coals and fractions received to date has been completed in order to obtain details of the iron mineralogy. The analyses of arsenic XAFS data for two of the project coals and for some high arsenic coals have been completed. Duplicate splits of the Ohio 5,6,7 and North Dakota lignite samples were taken through all four steps of the selective leaching procedure. Leaching analysis of the Wyodak coal has recently commenced. Preparation of polished coal/epoxy pellets for probe/SEM studies is underway. Some exploratory mercury LIII XAFS work was

  5. DOE solvent handbook information sheet

    Energy Technology Data Exchange (ETDEWEB)

    Chavez, A.A.

    1992-01-01

    Solvents and cleaners are used in the Department of Defense (DOD) and the Department of Energy-Defense Program (DOE-DP) maintenance facilities for removing wax, grease, oil, carbon, machining fluids, solder fluxes, mold releases, and other contaminants before repairing or electroplating parts. Private industry also uses cleaners and degreasers for surface preparation of various metals. Growing environmental and worker safety concerns have brought attention to these solvents and cleaners, most of which are classified as toxic. Tightening government regulations have already excluded the use of some chemicals, and restrict the use of various halogenated hydrocarbons because of their atmospheric-ozone depleting effects, as well as their cancer-related risks. As a result, a program was established to develop an efficient, easily accessible, electronic solvent utilization handbook. This is being accomplished by: (1) identifying solvents (alternatives) that are not currently restricted by government regulations for use DOE-DP facilities, and private industry, (2) evaluating their cleaning performance, (3) evaluating their corrosivity, (4) evaluating their air emissions, (5) evaluating the possibility of recycling or recovering all or portions of the alternative degreasers, (6) testing substitute solvents compatibility with non-metallic materials, (7) inputting all of the data gathered (including previous biodegradability information) into a database, and (8) developing a methodology for efficient, widespread access to the data base information system.

  6. DOE solvent handbook information sheet

    Energy Technology Data Exchange (ETDEWEB)

    Chavez, A.A.

    1992-05-01

    Solvents and cleaners are used in the Department of Defense (DOD) and the Department of Energy-Defense Program (DOE-DP) maintenance facilities for removing wax, grease, oil, carbon, machining fluids, solder fluxes, mold releases, and other contaminants before repairing or electroplating parts. Private industry also uses cleaners and degreasers for surface preparation of various metals. Growing environmental and worker safety concerns have brought attention to these solvents and cleaners, most of which are classified as toxic. Tightening government regulations have already excluded the use of some chemicals, and restrict the use of various halogenated hydrocarbons because of their atmospheric-ozone depleting effects, as well as their cancer-related risks. As a result, a program was established to develop an efficient, easily accessible, electronic solvent utilization handbook. This is being accomplished by: (1) identifying solvents (alternatives) that are not currently restricted by government regulations for use DOE-DP facilities, and private industry, (2) evaluating their cleaning performance, (3) evaluating their corrosivity, (4) evaluating their air emissions, (5) evaluating the possibility of recycling or recovering all or portions of the alternative degreasers, (6) testing substitute solvents compatibility with non-metallic materials, (7) inputting all of the data gathered (including previous biodegradability information) into a database, and (8) developing a methodology for efficient, widespread access to the data base information system.

  7. [Air pollution and cardiovascular disease].

    Science.gov (United States)

    Haber, Guy; Witberg, Guy; Danenberg, Haim

    2007-10-01

    Cardiovascular atherothrombosis is the most common cause of death globally, with several well-known risk factors. Air pollution is a byproduct of fuel combustion by motor vehicles, power plants and industrial factories. It is composed of gases, fluids and particulate matter (PM) of different sizes, which include basic carbon, organic carbonic molecules and metals such as vanadium, nickel, zinc and iron. These particles are subdivided by their median size, a major contributing factor for their capability to enter the human body through the respiratory system. Most of the epidemiological studies have shown correlation between acute and long-term exposure to air pollution elements and cardiovascular morbidity in general, and angina pectoris and acute myocardial infarction specifically. Physiological studies have found different arrhythmias as the etiologic cause of cardiovascular morbidity and mortality following exposure to air pollution. A major finding was a decline in heart rate variability, a phenomenon known as endangering for cardiovascular morbidity and mortality, especially in patients after acute myocardial infarction. To date, several pathways have been proposed, including a hypercoagulable state following an inflammatory response, cardiac nervous autonomic disequilibrium, endothelial dysfunction with blood vessel contraction and direct toxic impact on cardiac muscle. Additional research is needed for clarifying the pathophysiological pathways by which air pollution affects the cardiovascular system. That might allow forthcoming with preventive measures and correct treatment, and hence a decrease in cardiovascular morbidity and mortality. Another important target is dose-outcome correlation curves for safety threshold calculation as a basis for air pollution regulations.

  8. [Toxicity of monkshood. Review.].

    Science.gov (United States)

    Ingolfsdottir, K; Olafsson, K

    1997-03-01

    Monkshood, Aconitum napellus L. (Ranunculaceae), is considered one of the most poisonous plants growing in Europe. Monkshood and other Aconitum species are still used in Oriental and homeopathic medicine as analgesics, febrifuges and hypotensives. The neurotoxin aconitine is the principal alkaloid in most subspecies of monkshood. A review is presented, which includes historical aspects of monkshood as a poisonous and medicinal plant, the mode of action of aconitine, symptoms of toxicity, treatment and reports of recent poisoning incidents. In addition, results of quantitative HPLC examination of hypogeous and epigeous organs from a population of A. napellus ssp. vulgare cultivated in Iceland are discussed. The fact that children in Iceland have commonly been known to eat the sweet tasting nectaries in monkshood prompted an investigation of the alkaloidal content of these organs specifically. The low aconitine content found in the nectaries as well as in whole flowers accords with the absence of reported toxicity arising from the handling of flowers and consumption of nectaries from A. napellus in this country.

  9. Biochemical toxicity of benzene.

    Science.gov (United States)

    Rana, S V S; Verma, Yeshvandra

    2005-04-01

    Human exposure to benzene in work environment is a global occupational health problem. After inhalation or absorption, benzene targets organs viz. liver, kidney, lung, heart and brain etc. It is metabolized mainly in the liver by cytochrome P450 multifunctional oxygenase system. Benzene causes haematotoxicity through its phenolic metabolites that act in concert to produce DNA strand breaks, chromosomal damage, sister chromatid exchange, inhibition of topoisomerase II and damage to mitotic spindle. The carcinogenic and myelotoxic effects of benzene are associated with free radical formation either as benzene metabolites or lipid peroxidation products. Benzene oxide and phenol have been considered as proheptons. Liver microsomes play an important role in biotransformation of benzene whereas in kidney, it produces degenerative intracellular changes. Cohort studies made in different countries suggest that benzene induces multiple myeloma in petrochemical workers. Though extensive studies have been performed on its toxicity, endocrinal disruption caused by benzene remains poorly known. Transgenic cytochrome P450 IIE1 mice may help in understanding further toxic manifestations of benzene.

  10. Molecular toxicity of nanomaterials.

    Science.gov (United States)

    Chang, Xue-Ling; Yang, Sheng-Tao; Xing, Gengmei

    2014-10-01

    With the rapid developments in the fields of nanoscience and nanotechnlogy, more and more nanomaterials and their based consumer products have been used into our daily life. The safety concerns of nanomaterials have been well recognized by the scientific community and the public. Molecular mechanism of interactions between nanomaterials and biosystems is the most essential topic and final core of the biosafety. In the last two decades, nanotoxicology developed very fast and toxicity phenomena of nanomaterials have been reported. To achieve better understanding and detoxication of nanomaterials, thorough studies of nanotoxicity at molecular level are important. The interactions between nanomaterials and biomolecules have been widely investigated as the first step toward the molecular nanotoxicology. The consequences of such interactions have been discussed in the literature. Besides this, the chemical mechanism of nanotoxicology is gaining more attention, which would lead to a better design of nontoxic nanomaterials. In this review, we focus on the molecular nanotoxicology and explore the toxicity of nanomaterials at molecular level. The molecular level studies of nanotoxicology are summarized and the published nanotoxicological data are revisited.

  11. GSPEL - Air Filtration Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Evaluation capabilities for air filtration devices The Air Filtration Lab provides testing of air filtration devices to demonstrate and validate new or legacy system...

  12. Norma Primaria de calidad del aire AIR QUALITY STANDARD

    Directory of Open Access Journals (Sweden)

    PATRICIA MATUS C.

    2002-04-01

    Full Text Available Las normas primarias de calidad del aire tienen por finalidad proteger la salud de la población de la contaminación atmosférica. Ellas establecen un nivel de riesgo socialmente aceptado. Este artículo describe los antecedentes considerados durante el proceso de actualización de la regulación vigente en Chile. Detalla conceptos sobre la calidad del aire, describe los efectos en la salud de los contaminantes, y el procedimiento seguido para fijar los nuevos estándares Finaliza enumerando la norma primaria de calidad del aire, sus valores y los limites definidos para ser considerados en el ámbito de la gestión de los episodios críticos o de alta contaminaciónThe main purpose of air quality standards is to protect people health from air pollution. They establish a socially accepted level of risk. This article describes the background information considered during the process for updating the current Chilean regulation. Concepts about quality of air, and the effects of the pollutants on the health are described. The procedure followed to fix the new standards is detailed. Finally we state the primary air quality norm, its values as well as the critical limits in order to control critical events of high air pollution

  13. Status and applications of echinoid (phylum echinodermata) toxicity test methods

    Energy Technology Data Exchange (ETDEWEB)

    Bay, S.; Burgess, R.; Nacci, D.

    1993-01-01

    The use of echinoderms for toxicity testing has focused primarily on sea urchins and sand dollars (Strongylocentrotus purpuratus, Arbacia punctulata, Lytechinus pictus, and Dendraster excentricus, for example). The status and relative sensitivity of various test methods are described. The most frequently used test methods consist of short-term exposures of sea urchin sperm or embryos; these tests can be easily conducted at all times of the year by using species with complementary spawning cycles or laboratory conditioned populations of a single species. Data from reference toxicant and effluent toxicity tests are summarized. Information on the precision and sensitivity of echinoid test methods are limited and preclude rigorous comparisons with other test methods. The available data indicate that the sensitivity and precision of these methods are comparable to short-term chronic methods for other marine invertebrates and fish. Recent application of the sperm test in toxicity identification evaluations (TIEs) and studies of effluent toxicity decay and sediment toxicity illustrate the versatility of this rapid (10 to 60 min exposure) test method. Embryo tests typically use a 48 to 96 h exposure period and measure the occurrence of embryo malformations. Most recent applications of the embryo test have been for the assessment of sediment elutriate toxicity. Adult echinoderms are not frequently used to assess effluent or receiving water toxicity. Recent studies have had success in using the adult life stage of urchins and sand dollars to assess the effects of contaminated sediment on growth, behavior, and bioaccumulation.

  14. Chronic Exposure to Diquat Causes Reproductive Toxicity in Female Mice

    OpenAIRE

    Jia-Qing Zhang; Bin-Wen Gao; Jing Wang; Xian-Wei Wang; Qiao-Ling Ren; Jun-Feng Chen; Qiang Ma; Bao-Song Xing

    2016-01-01

    Diquat is a bipyridyl herbicide that has been widely used as a model chemical for in vivo studies of oxidative stress due to its generation of superoxide anions, and cytotoxic effects. There is little information regarding the toxic effects of diquat on the female reproductive system, particularly ovarian function. Thus, we investigated the reproductive toxic effects of diquat on female mice. Chronic exposure to diquat reduced ovary weights, induced ovarian oxidative stress, resulted in granu...

  15. Air-to-Air Missile Vector Scoring

    Science.gov (United States)

    2012-03-22

    64 4.6. Unscented Kalman Filter Performance in Air-to-Air Missile Scor - ing Application with Continuous Velocity Dynamics Model (Tar- get...Filter Performance in Air-to-Air Missile Scor - ing Application with Continuous Velocity Dynamics Model (Tar- get Aircraft Executing a Vertical Climb...Kalman Filter Performance in Air-to-Air Missile Scor - ing Application with Continuous Velocity Dynamics Model (Tar- get Aircraft Non-maneuvering

  16. Inform@ed space

    DEFF Research Database (Denmark)

    Bjerrum, Peter; Olsen, Kasper Nefer

    2001-01-01

    Inform@ed space Sensorial Perception And Computer Enchancement - bidrag til Nordisk Arkitekturforskningsforenings IT-konference, AAA april 2001.......Inform@ed space Sensorial Perception And Computer Enchancement - bidrag til Nordisk Arkitekturforskningsforenings IT-konference, AAA april 2001....

  17. Inflammatory and toxic myopathies.

    Science.gov (United States)

    Dalakas, M C

    1992-10-01

    The major advances in the immunopathogenesis and treatment of inflammatory myopathies, and the main criteria that distinguish polymyositis (PM) from dermatomyositis (DM) or inclusion-body myositis (IBM) are presented. The origin and implications of the amyloid and ubiquitin deposits found within the vacuolated fibers of patients with IBM are considered. The pathogenesis of human immunodeficiency virus (HIV) and human T-cell lymphotrophic virus (HTLV)-I-associated PM is presented, and the role of retroviruses in triggering PM, even in the absence of detectable viral genome within the muscle fibers, is discussed. In addition, three toxic myopathies with distinct morphologic, biochemical, or molecular characteristics, caused by zidovudine [azidothymidine (AZT) myopathy], the cholesterol-lowering-agent myopathy (CLAM), and the combination of blocking agents with corticosteroids are presented.

  18. R9 Air Districts

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Region 9 Air Districts layer is a compilation of polygons representing the California Air Pollution Control and Air Quality Management Districts, Arizona Air...

  19. California Air Basins

    Data.gov (United States)

    California Department of Resources — Air ResourcesCalifornia Air Resources BoardThe following datasets are from the California Air Resources Board: * arb_california_airbasins - California Air BasinsThe...

  20. 基于红外光谱分区的多溴联苯醚辨识及生物毒性特征光谱信息提取研究%Study on Identification of PBDEs and Characteristic Information Extraction of Biological Toxicity Based on Infrared Spectrum Partition

    Institute of Scientific and Technical Information of China (English)

    姜龙; 李鱼

    2016-01-01

    In this paper,9 most abundant PBDE congeners in environment and 14 congeners with high/medium biological toxicity were selected as target compounds.Firstly,IR spectra of 23 compounds were divided into 6 spectrum regions based on known vibrational assignment,and their identification abilities for PBDEs were evaluated by using similarity analysis.Then,the spec-trum regions with high identification ability relatively have been analyzed to search identification method on the basis of each spectrum characteristic.At last,the principal component analysis and discriminant analysis method were used to extract charac-teristic spectrum information of congeners with high/medium biological toxicity and establish biological toxicity discriminant model.The triangle breathing vibration region (961~1 153 cm-1 )and C—O stretching vibration region (1 153~1 346 cm-1 ) has been filtered as characteristic IR spectrum regions because of smaller similarity among PBDEs relatively.For the former,the information of vibration peaks distribution can be taken as tool to identification,with the smallest frequency difference of 3.1 9 cm-1 among 23 congeners and bad ability to distinguish PBDEs from dioxin-similar compounds.For the later,the frequency and shape of main peak is as mark and the smallest frequency difference among PBDEs and between PBDEs with dioxin-similar com-pounds are 0.74 and 0.67 cm-1 separately,both larger than the common minimum resolution of IR spectrum 0.5 cm-1 ,depic-ting good ability for both inner and outer identification of PBDEs.The established biological toxicity discriminant model via dis-criminant analysis also have shown well ability to biological toxicity prediction,with accuracy of 100% and 88.9% for high/me-dium and low biological toxicity relatively,representing the extracted IR spectrum information from congeners with high/medium toxicity can realize the accurate classification of biological toxicity for PBDEs.%选取环境中含量最多的9种多溴联

  1. Lead toxicity: Current concerns

    Energy Technology Data Exchange (ETDEWEB)

    Goyer, R.A. (Univ. of Western Ontario, London (Canada))

    1993-04-01

    Over the 20-year period since the first issue of Environmental Health Perspectives was published, there has been considerable progress in the understanding of the potential toxicity of exposure to lead. Many of these advances have been reviewed in published symposia, conferences, and review papers in EHP. This brief review identifies major advances as well as a number of current concerns that present opportunities for prevention and intervention strategies. The major scientific advance has been the demonstration that blood lead (PbB) levels of 10-15 micrograms/dL in newborn and very young infants result in cognitive and behavioral deficits. Further support for this observation is being obtained by prospective or longitudinal studies presently in progress. The mechanism(s) for the central nervous system effects of lead is unclear but involve lead interactions within calcium-mediated intracellular messenger systems and neurotransmission. Effects of low-level lead exposure on blood pressure, particularly in adult men, may be related to the effect of lead on calcium-mediated control of vascular smooth muscle contraction and on the renin-angiotensin system. Reproductive effects of lead have long been suspected, but low-level effects have not been well studied. Whether lead is a carcinogen or its association with renal adenocarcinoma is a consequence of cystic nephropathy is uncertain. Major risk factors for lead toxicity in children in the United States include nutrition, particularly deficiencies of essential metals, calcium, iron, and zinc, and housing and socioeconomic status. A goal for the year 2000 is to reduce prevalence of blood lead levels exceeding 15 micrograms/dL. 97 refs.

  2. Information Systems Strategy in Air Transport

    Science.gov (United States)

    1993-09-01

    Balance at December 31. 14% -42.412 81.11- 484.i-59 t33o-) 60..851 Issuance of common and treat.u, stock upon exercise of executive stock options and...treasury stock upon exercise of executive stock options and pursuant to emplo’ee stock option and purchase plans (Note 9) 156 3,359 - 553 4,068 Cash

  3. Assessing the potential toxicity of new pharmaceuticals.

    Science.gov (United States)

    Johnson, D E; Wolfgang, G H

    2001-09-01

    Optimizing chemical structures to create potentially safe drugs during discovery and early development relies on a combination of predictive algorithms, screening, formal toxicology studies, and early clinical trials. Early in the process three critical questions emerge that must be answered by a detailed "profiling" approach. These questions are: 1) is there a correlation between the chemical structure and potential toxicity that can be used to optimize structures of lead compounds, 2) can specific markers of potential toxicity can be identified carly and used as mechanistic decision-making screens, and 3) will exposures (plasma levels) in animal studies correlate with exposures encountered in the clinic thereby providing "coverage" for safety? Depending on the therapeutic class of compounds being considered and the level of knowledge available, feedback loops of information can be established to guide the development process.

  4. Nanomaterials and nanoparticles : Sources and toxicity

    CERN Document Server

    Buzea, Cristina; Robbie, Kevin

    2008-01-01

    This review is written with the goal of informing public health concerns related to nanoscience, while raising awareness of nanomaterials toxicity among scientists and manufacturers handling them. We show that humans have always been exposed to nanoparticles and dust from natural sources and human activities, the recent development of industry and combustion-based engine transportation profoundly increasing anthropogenic nanoparticulate pollution. The key to understanding the toxicity of nanoparticles is that their minute size, smaller than cells and cellular organelles, allows them to penetrate these basic biological structures, disrupting their normal function. Among diseases associated with nanoparticles are asthma, bronchitis, lung cancer, neurodegenerative diseases (such as Parkinson`s and Alzheimer`s diseases), Crohn`s disease, colon cancer. Nanoparticles that enter the circulatory system are related to occurrence of arteriosclerosis, and blood clots, arrhythmia, heart diseases, and ultimately cardiac d...

  5. Systematic Review of Radiation Therapy Toxicity Reporting in Randomized Controlled Trials of Rectal Cancer: A Comparison of Patient-Reported Outcomes and Clinician Toxicity Reporting

    Energy Technology Data Exchange (ETDEWEB)

    Gilbert, Alexandra, E-mail: a.gilbert@leeds.ac.uk [Leeds Institute of Cancer & Pathology, University of Leeds, Leeds (United Kingdom); Ziegler, Lucy; Martland, Maisie [Leeds Institute of Cancer & Pathology, University of Leeds, Leeds (United Kingdom); Davidson, Susan [The Christie Hospital, Manchester (United Kingdom); Efficace, Fabio [Italian Group for Adult Hematologic Diseases, Rome (Italy); Sebag-Montefiore, David; Velikova, Galina [Leeds Institute of Cancer & Pathology, University of Leeds, Leeds (United Kingdom)

    2015-07-01

    The use of multimodal treatments for rectal cancer has improved cancer-related outcomes but makes monitoring toxicity challenging. Optimizing future radiation therapy regimens requires collection and publication of detailed toxicity data. This review evaluated the quality of toxicity information provided in randomized controlled trials (RCTs) of radiation therapy in rectal cancer and focused on the difference between clinician-reported and patient-reported toxicity. Medline, EMBASE, and the Cochrane Library were searched (January 1995-July 2013) for RCTs reporting late toxicity in patients treated with regimens including preoperative (chemo)radiation therapy. Data on toxicity measures and information on toxicity reported were extracted using Quantitative Analyses of Normal Tissue Effects in the Clinic recommendations. International Society for Quality of Life Research standards on patient-reported outcomes (PROs) were used to evaluate the quality of patient-reported toxicity. Twenty-one RCT publications met inclusion criteria out of 4144 articles screened. All PRO studies reported higher rates of toxicity symptoms than clinician-reported studies and reported on a wider range and milder symptoms. No clinician-reported study published data on sexual dysfunction. Of the clinician-reported studies, 55% grouped toxicity data related to an organ system together (eg “Bowel”), and 45% presented data only on more-severe (grade ≥3) toxicity. In comparison, all toxicity grades were reported in 79% of PRO publications, and all studies (100%) presented individual symptom toxicity data (eg bowel urgency). However, PRO reporting quality was variable. Only 43% of PRO studies presented baseline data, 28% did not use any psychometrically validated instruments, and only 29% of studies described statistical methods for managing missing data. Analysis of these trials highlights the lack of reporting standards for adverse events and reveals the differences between clinician and

  6. Air quality in Europe - 2011 report

    Energy Technology Data Exchange (ETDEWEB)

    Guerreiro, C.; Larssen, S. (Norsk Inst. for Luftforskning (NILU), Lillestroem (Norway)); Leeuw, F. de (RIVM, Bilthoven (Netherlands)); Foltescu, V. (EEA, Copenhagen (Denmark))

    2011-11-15

    The annual report 'Air quality in Europe' summarises the most recent evaluation of Europe's air quality status. It is mainly based on air quality measurement data that have been made available officially by 32 EEA member countries as well as 6 EEA cooperating countries. The report includes maps and analyses of air quality status over the calendar year 2009. It also analyses air quality trends over the past years. The evaluation of the status and trends of air quality is based on ambient air measurements, in conjunction with reported anthropogenic emissions. The report summarizes the main effects of different air pollutants on human health, the environment and the climate. An overview of policies and measures at European level is also given for each pollutant. This report reviews progress towards meeting the requirements of the two air quality directives in force as well as the air quality guidelines set by the World Health Organization (WHO). The report is produced in support of European and national policy development and implementation in the field of air quality. It also supports air quality management and informs the general public on the current status and trends of air quality in Europe. (Author)

  7. Air transport system

    CERN Document Server

    Schmitt, Dieter

    2016-01-01

    The book addresses all major aspects to be considered for the design and operation of aircrafts within the entire transportation chain. It provides the basic information about the legal environment, which defines the basic requirements for aircraft design and aircraft operation. The interactions between  airport, air traffic management and the airlines are described. The market forecast methods and the aircraft development process are explained to understand the very complex and risky business of an aircraft manufacturer. The principles of flight physics as basis for aircraft design are presented and linked to the operational and legal aspects of air transport including all environmental impacts. The book is written for graduate students as well as for engineers and experts, who are working in aerospace industry, at airports or in the domain of transport and logistics.

  8. Developmental toxicity of engineered nanomaterials in rodents.

    Science.gov (United States)

    Ema, Makoto; Gamo, Masashi; Honda, Kazumasa

    2016-05-15

    We summarized significant effects reported in the literature on the developmental toxicity of engineered nanomaterials (ENMs) in rodents. The developmental toxicity of ENMs included not only structural abnormalities, but also death, growth retardation, and behavioral and functional abnormalities. Most studies were performed on mice using an injection route of exposure. Teratogenic effects were indicated when multi-walled carbon nanotubes (MWCNTs), single-walled carbon nanotubes (SWCNTs), and TiO2-nanoparticles were administered to mice during early gestation. Reactive oxygen species levels were increased in placentas and malformed fetuses and their placentas after prenatal exposure to MWCNTs and SWCNTs, respectively. The pre- and postnatal mortalities and growth retardation in offspring increased after prenatal exposure to ENMs. Histopathological and functional abnormalities were also induced in placentas after prenatal exposure to ENMs. Maternal exposure to ENMs induced behavioral alterations, histopathological and biochemical changes in the central nervous system, increased susceptibility to allergy, transplacental genotoxicity, and vascular, immunological, and reproductive effects in offspring. The size- and developmental stage-dependent placental transfer of ENMs was noted after maternal exposure. Silver accumulated in the visceral yolk sac after being injected with Ag-NPs during early gestation. Although currently available data has provided initial information on the potential developmental toxicity of ENMs, that on the developmental toxicity of ENMs is still very limited. Further studies using well-characterized ENMs, state-of the-art study protocols, and appropriate routes of exposure are required in order to clarify these developmental effects and provide information suitable for risk assessments of ENMs.

  9. Air Warfare

    Science.gov (United States)

    2002-03-01

    undoubtedly begat the shield; poisonous gases were countered by the mask. Surely men on the surface of the earth will not have to submit to violent air attack...properties, production methods and cost of helium are given in “Balloon and Airship Gases ,” a volume of the Ronald Aeronautic Library. 5 More complete...becomes and more inse - cure. We shall see later that even some of the men who were advancing in the path prescribed by the principle of mass

  10. Toxic encephalopathy induced by capecitabine.

    Science.gov (United States)

    Niemann, B; Rochlitz, C; Herrmann, R; Pless, M

    2004-01-01

    Toxic encephalopathy is a rarely described side effect of 5-fluorouracil which usually presents with cerebellar, neuropsychiatric, and focal neurological symptoms. Magnetic resonance imaging findings are described as patchy white matter alterations. We report the 1st case of capecitabine-induced toxic encephalopathy with epilepsy-like symptoms and diffuse white matter alterations on magnetic resonance imaging.

  11. Information resources: How they are utilized by Louisiana

    Energy Technology Data Exchange (ETDEWEB)

    Gardner, S. [Louisiana Department of Environmental Quality, Baton Rouge (United States)

    1990-12-31

    Louisiana, now in a developmental stage of policy and planning, has completed a project aimed at reducing hazardous releases of air toxics in thee state. The state is also conducting a Comparative Risk Project and is using risk assessment practices to develop its waste quality standards. In developing an air toxic list, Louisiana incorporated four major criteria into the ranking: emission levels, human health effects, potential population exposure, and persistence or accumulation in the environment. For the human health effects criterion, data for each substance was gathered from numerous sources, although the Integrated Risk Information System (IRIS) database was used as a primary source for toxicological information. Following guidelines established by the Environmental Protection Agency (EPA), the Office of Water Resources, Water Pollution Control Division, has developed numerical criteria for human health protection based on risk assessment procedures in the 1989 Water Quality Standards Revision. Currently over 30 toxic substances have risk-based criteria for th protection of human health in the standards. Numerical criteria were calculated for carcinogenic substances having an EPA Classification of A, B1, B2, or C. Cancer class designations along with cancer potency slopes and reference doses were extracted from the IRIS database, with the exception of those chemicals that had not been assessed in IRIS as of December 1, 1988. The parameters necessary for calculating human health criteria for the missing chemicals were taken from 1980, 1984, and 1985 ambient water quality criteria documents: data on bioconcentration factors were included. Currently, Louisiana is working on a Comparative Risk Project, a ranking of the environmental issues in the state relative to potential risk to the public, which is the basis for a widespread 1991 public outreach effort.

  12. VARIATIONS IN REPRODUCTIVE TOXICANT IDENTIFICATION

    Energy Technology Data Exchange (ETDEWEB)

    Simmons, F

    2008-05-13

    Reproductive toxicants are a very important class of compounds. They present unique hazards to those of child bearing ages, perform their 'dirty work' using a wide variety of mechanisms on a number of different organs, and are regulatorily important. Because of all of this, properly identifying reproductive toxicants is important, but fraught with difficulty. In this paper we will describe types or reproductive toxicants, their importance, and both mistakes and good practices that people who are not experts in reproductive toxicology may use in their attempts to identify them. Additionally, this paper will focus on chemical reproductive toxicants and will not address biological agents that could affect reproductive toxicity although many principles outlined here could be applied to that endeavor.

  13. The use of in vitro toxicity data and physiologically based kinetic modeling to predict dose-response curves for in vivo developmental toxicity of glycol ethers in rat and man.

    NARCIS (Netherlands)

    Louisse, J.; de Jong, E.; van de Sandt, J.J.M.; Blaauboer, B.J.; Woutersen, R.A.; Piersma, A.H.; Rietjens, I.M.C.M.; Verwei, M.

    2010-01-01

    At present, regulatory assessment of systemic toxicity is almost solely performed using animal models. The EU REACH legislation stimulates the use of animal-free approaches to obtain information on the toxicity of chemicals. In vitro toxicity tests provide in vitro concentration-response curves for

  14. The use of in vitro toxicity data and physiologically based kinetic modeling to predict dose-response curves for in vivo developmental toxicity of glycol ethers in rat and man

    NARCIS (Netherlands)

    Louisse, J.; Jong, E. de; Sandt, J.J.M. van de; Blaauboer, B.J.; Woutersen, R.A.; Piersma, A.H.; Rietjens, I.M.C.M.; Verwei, M.

    2010-01-01

    At present, regulatory assessment of systemic toxicity is almost solely carried out using animal models. The European Commission's REACH legislation stimulates the use of animal-free approaches to obtain information on the toxicity of chemicals. In vitro toxicity tests provide in vitro concentration

  15. The use of in vitro toxicity data and physiologically based kinetic modeling to predict dose-respomse curves for in vivo developmental toxicity of glycol ethers in rat and man

    NARCIS (Netherlands)

    Louisse, J.; Jong, de E.; Sandt, van de J.J.M.; Blaauboer, B.J.; Woutersen, R.A.; Piersma, A.H.; Rietjens, I.; Verwei, M.

    2010-01-01

    At present, regulatory assessment of systemic toxicity is almost solely performed using animal models. The EU REACH legislation stimulates the use of animal-free approaches to obtain information on the toxicity of chemicals. In vitro toxicity tests provide in vitro concentration-response curves for

  16. Review of Quantitative Structure - Activity Relationships for Acute Mammalian Toxicity

    Directory of Open Access Journals (Sweden)

    Iglika Lessigiarska

    2006-12-01

    Full Text Available This paper reviews Quantitative Structure-Activity Relationship (QSAR models for acute mammalian toxicity published in the last decade. A number of QSAR models based on cytotoxicity data from mammalian cell lines are also included because of their possible use as a surrogate system for predicting acute toxicity to mammals. On the basis of the review, the following conclusions can be made: i a relatively small number of models for in vivo toxicity are published in the literature. This is due to the nature of the endpoint - acute systemic toxicity is usually related to whole body phenomena and therefore is very complex. The complexity of the mechanisms involved leads to difficulties in the QSAR modelling; ii most QSAR models identify hydrophobicity as a parameter of high importance for the modelled toxicity. In addition, many models indicate the role of the electronic and steric effects; iii most of the literature-based models are restricted to single chemical classes. Models based on more heterogeneous data sets are those incorporated in expert systems. In general, the QSAR models for mammalian toxicity identified in this review are considered useful for investigating the mechanisms of toxicity of defined chemical classes. However, for predictive purposes in the regulatory assessment of chemicals most of the models require additional information to satisfy internationally agreed validation principles. In addition, the development of new models covering larger chemical domains would be useful for the regulatory assessment of chemicals.

  17. Toxic species in amyloid disorders: Oligomers or mature fibrils

    Directory of Open Access Journals (Sweden)

    Meenakshi Verma

    2015-01-01

    Full Text Available Protein aggregation is the hallmark of several neurodegenerative disorders. These protein aggregation (fibrillization disorders are also known as amyloid disorders. The mechanism of protein aggregation involves conformation switch of the native protein, oligomer formation leading to protofibrils and finally mature fibrils. Mature fibrils have long been considered as the cause of disease pathogenesis; however, recent evidences suggest oligomeric intermediates formed during fibrillization to be toxic. In this review, we have tried to address the ongoing debate for these toxic amyloid species. We did an extensive literature search and collated information from Pubmed (http://www.ncbi.nlm.nih.gov and Google search using various permutations and combinations of the following keywords: Neurodegeneration, amyloid disorders, protein aggregation, fibrils, oligomers, toxicity, Alzheimer′s Disease, Parkinson′s Disease. We describe different instances showing the toxicity of mature fibrils as well as oligomers in Alzheimer′s Disease and Parkinson′s Disease. Distinct structural framework and morphology of amyloid oligomers suggests difference in toxic effect between oligomers and fibrils. We highlight the difference in structure and proposed toxicity pathways for fibrils and oligomers. We also highlight the evidences indicating that intermediary oligomeric species can act as potential diagnostic biomarker. Since the formation of these toxic species follow a common structural switch among various amyloid disorders, the protein aggregation events can be targeted for developing broad-range therapeutics. The therapeutic trials based on the understanding of different protein conformers (monomers, oligomers, protofibrils and fibrils in amyloid cascade are also described.

  18. CAirTOX, An inter-media transfer model for assessing indirect exposures to hazardous air contaminants

    Energy Technology Data Exchange (ETDEWEB)

    McKone, T.E.

    1994-01-01

    Risk assessment is a quantitative evaluation of information on potential health hazards of environmental contaminants and the extent of human exposure to these contaminants. As applied to toxic chemical emissions to air, risk assessment involves four interrelated steps. These are (1) determination of source concentrations or emission characteristics, (2) exposure assessment, (3) toxicity assessment, and (4) risk characterization. These steps can be carried out with assistance from analytical models in order to estimate the potential risk associated with existing and future releases. CAirTOX has been developed as a spreadsheet model to assist in making these types of calculations. CAirTOX follows an approach that has been incorporated into the CalTOX model, which was developed for the California Department of Toxic Substances Control, With CAirTOX, we can address how contaminants released to an air basin can lead to contamination of soil, food, surface water, and sediments. The modeling effort includes a multimedia transport and transformation model, exposure scenario models, and efforts to quantify uncertainty in multimedia, multiple-pathway exposure assessments. The capacity to explicitly address uncertainty has been incorporated into the model in two ways. First, the spreadsheet form of the model makes it compatible with Monte-Carlo add-on programs that are available for uncertainty analysis. Second, all model inputs are specified in terms of an arithmetic mean and coefficient of variation so that uncertainty analyses can be carried out.

  19. Cleaning products and air fresheners: exposure to primary and secondary air pollutants

    DEFF Research Database (Denmark)

    Nazaroff, W.; Weschler, Charles J.

    2004-01-01

    . More than two dozen research articles present evidence of adverse health effects from inhalation exposure associated with cleaning or cleaning products. Exposure to primary and secondary pollutants depends on the complex interplay of many sets of factors and processes, including cleaning product...... by the US federal government as hazardous air pollutants (HAPs). California's Proposition 65 list of species recognized as carcinogens or reproductive toxicants also includes constituents of certain cleaning products and air fresheners. In addition, many cleaning agents and air fresheners contain chemicals...... that can react with other air contaminants to yield potentially harmful secondary products. For example, terpenes can react rapidly with ozone in indoor air generating many secondary pollutants, including TACs such as formaldehyde. Furthermore, ozone-terpene reactions produce the hydroxyl radical, which...

  20. Air Contamination With Fungals In Museum

    Science.gov (United States)

    Scarlat, Iuliana; Haiducu, Maria; Stepa, Raluca

    2015-07-01

    The aim of the studies was to determine the level and kind of fungal contamination of air in museum, deposits patrimony, restoration and conservation laboratories and their effects on health of workers. Microbiological air purity was measured with a SAS-100 Surface Air System impactor. The fungal contamination was observed in all 54 rooms where we made determinations. The highest levels of fungal were recorded at rooms with hygroscopic patrimony objects, eg carpets, chairs, upholstered chairs, books etc. The most species identified included under common allergens: Aspergillus, Penicillium, and Mucor. There fungal species belonging to the genus identified in this study, can trigger serious diseases museum workers, such as for example Aspergillus fumigatus, known allergies and toxic effects that may occur. In some places of the museum, occupational exposure limit values to fungi present in the air in the work environment, recommended by the specialized literature, have been overcome.

  1. [Toxicity of sulpiride].

    Science.gov (United States)

    Ciszowski, Krzysztof; Szpak, Dorota; Wilimowska, Jolanta

    2010-01-01

    Sulpiride is a benzamide neuroleptic used in the treatment of some psychiatric and gastroenterological disorders. Its antipsychotic, antiautistic, activizing and antidepressive properties result from antagonistic action to dopaminergic D2, D3 and D4 receptors in the central nervous system (CNS). The oral bioavailability of sulpiride is poor and it does not appear to have an extensive first-pass metabolism, nor is it extensively protein-bound. Elimination of sulpiride appears to depend primarily on the kidneys. The acute sulpiride poisoning includes mainly neuropsychiatric (i.e., agitation, hallucinations, and CNS depression) as well as cardiac effects (i.e., hypotension, dysrhythmias, and sinus tachycardia). The life-threatening conditions with sometimes fatal outcome after sulpiride poisoning are prolongation of QTc interval with consequent torsade de pointes (TdP) and neuroleptic malignant syndrome (NMS). The quantitative methods for the measurement of sulpiride blood concentration are not routinely available and the toxic blood concentration is probably higher than 2 mg/L. Treatment of acute sulpiride poisoning includes standard protocols of gastrointestinal decontamination and further symptomatic and supportive measures, among them TdP (magnesium sulphate, isoproterenol, electrotherapy) and NMS treatment (benzodiazepines, bromocriptine, dantrolene, physical cooling).

  2. Toxic epidermal necrolysis.

    Science.gov (United States)

    Castelain, Florence; Humbert, Philippe

    2012-11-01

    Toxic epidermal necrolysis (TEN) is a severe mucocutaneous drug-induced syndrome that causes massive keratinocyte apoptosis and therefore hydro-electrolytic disorders and systemic infection. TEN approximately affects one to two cases per million per year. Mortality rate may reach thirty percent of cases. Thus, TEN constitutes a therapeutic emergency at diagnosis. Typically, clinical examination shows a mucocutaneous detachment involving more than thirty percent of body area. Definitive diagnosis is made on cutaneous biopsy with histological exam that shows the blister of necrotic keratinocytes. Main differential diagnosis are acute staphylococcus epidermis, acute generalized exanthematous pustulosis, linear IgA bullous dermatosis, paraneoplastic pemphigus, bullous fixed pigmented erythema, acute lupus erythematosus. In the early days, SCORTEN gives a good estimation and is now widely used as prognostic score. Drugs are generally considered as the main etiology of TEN but in some cases bacterial or viral infections could be involved. Physiopathology remains unclear even if recent advances have reported the possible implication of immune pathways based on activation of T and NK cells. Treatment of TEN requires to be instituted as soon as the diagnosis is made and the patient is preferentially referred to a specialized unit. Supportive care consist of covering areas of cutaneous detachment. No other therapy has demonstrated its efficiency, but high-dose intravenous immunoglobulin might improve the prognosis.

  3. Measuring Concentrations of Particulate 140La in the Air

    Energy Technology Data Exchange (ETDEWEB)

    Okada, Colin E.; Kernan, Warnick J.; Keillor, Martin E.; Kirkham, Randy R.; Sorom, Rich D.; Van Etten, Don M.

    2016-05-01

    Air sampling systems were deployed to measure the concentration of radioactive material in the air during the Full-Scale Radiological Dispersal Device experiments. The air samplers were positioned 100-600 meters downwind of the release point. The filters were collected immediately and analyzed in the field. Quantities for total activity collected on the air filters are reported along with additional information to compute the average or integrated air concentrations.

  4. Extensive air showers

    CERN Document Server

    Rao, M V S

    1997-01-01

    Ultrahigh energy cosmic rays carry information about their sources and the intervening medium apart from providing a beam of particles for studying certain features of high energy interactions currently inaccessible at man-made accelerators. They can at present be studied only via the extensive air showers (EAS's) they generate while passing through the Earth's atmosphere, since their fluxes are too low for the experiments of limited capability flown in balloons and satellites. The EAS is generated by a series of interactions of the primary cosmic ray and its progeny with the atmospheric nucle

  5. 77 FR 60985 - Ambient Air Monitoring Reference and Equivalent Methods: Designation of Three New Equivalent Methods

    Science.gov (United States)

    2012-10-05

    ... AGENCY Ambient Air Monitoring Reference and Equivalent Methods: Designation of Three New Equivalent... methods for monitoring ambient air quality. SUMMARY: Notice is hereby given that the Environmental... in the ambient air. FOR FURTHER INFORMATION CONTACT: Robert Vanderpool, Human Exposure...

  6. Air Leakage and Air Transfer Between Garage and Living Space

    Energy Technology Data Exchange (ETDEWEB)

    Rudd, A.

    2014-09-01

    This research project focused on evaluation of air transfer between the garage and living space in a single-family detached home constructed by a production homebuilder in compliance with the 2009 International Residential Code and the 2009 International Energy Conservation Code. The project gathered important information about the performance of whole-building ventilation systems and garage ventilation systems as they relate to minimizing flow of contaminated air from garage to living space. A series of 25 multi-point fan pressurization tests and additional zone pressure diagnostic testing characterized the garage and house air leakage, the garage-to-house air leakage, and garage and house pressure relationships to each other and to outdoors using automated fan pressurization and pressure monitoring techniques. While the relative characteristics of this house may not represent the entire population of new construction configurations and air tightness levels (house and garage) throughout the country, the technical approach was conservative and should reasonably extend the usefulness of the results to a large spectrum of house configurations from this set of parametric tests in this one house. Based on the results of this testing, the two-step garage-to-house air leakage test protocol described above is recommended where whole-house exhaust ventilation is employed. For houses employing whole-house supply ventilation (positive pressure) or balanced ventilation (same pressure effect as the Baseline condition), adherence to the EPA Indoor airPLUS house-to-garage air sealing requirements should be sufficient to expect little to no garage-to-house air transfer.

  7. TOXIC SUBSTANCES FROM COAL COMBUSTION-A COMPREHENSIVE ASSESSMENT

    Energy Technology Data Exchange (ETDEWEB)

    C.L. Senior; F. Huggins; G.P. Huffman; N. Shah; N. Yap; J.O.L. Wendt; W. Seames; M.R. Ames; A.F. Sarofim; S. Swenson; J.S. Lighty; A. Kolker; R. Finkelman; C.A. Palmer; S.J. Mroczkowski; J.J. Helble; R. Mamani-Paco; R. Sterling; G. Dunham; S. Miller

    2001-06-30

    The Clean Air Act Amendments of 1990 identify a number of hazardous air pollutants (HAPs) as candidates for regulation. Should regulations be imposed on HAP emissions from coal-fired power plants, a sound understanding of the fundamental principles controlling the formation and partitioning of toxic species during coal combustion will be needed. With support from the National Energy Technology Laboratory (NETL), the Electric Power Research Institute, and VTT (Finland), Physical Sciences Inc. (PSI) has teamed with researchers from USGS, MIT, the University of Arizona (UA), the University of Kentucky (UK), the University of Connecticut (UC), the University of Utah (UU) and the University of North Dakota Energy and Environmental Research Center (EERC) to develop a broadly applicable emissions model useful to regulators and utility planners. The new Toxics Partitioning Engineering Model (ToPEM) will be applicable to all combustion conditions including new fuels and coal blends, low-NOx combustion systems, and new power generation plants. Development of ToPEM will be based on PSI's existing Engineering Model for Ash Formation (EMAF). The work discussed in this report covers the Phase II program. Five coals were studied (three in Phase I and two new ones in Phase II). In this work UK has used XAFS and Moessbauer spectroscopies to characterize elements in project coals. For coals, the principal use was to supply direct information about certain hazardous and other key elements (iron) to complement the more complete indirect investigation of elemental modes of occurrence being carried out by colleagues at USGS. Iterative selective leaching using ammonium acetate, HCl, HF, and HNO3, used in conjunction with mineral identification/quantification, and microanalysis of individual mineral grains, has allowed USGS to delineate modes of occurrence for 44 elements. The Phase II coals show rank-dependent systematic differences in trace-element modes of occurrence. The work at

  8. Determination and evaluation of air quality control. Manual of ambient air quality control in Germany

    Energy Technology Data Exchange (ETDEWEB)

    Lahmann, E.

    1997-07-01

    Measurement of air pollution emissions and ambient air quality are essential instruments for air quality control. By undertaking such measurements, pollutants are registered both at their place of origin and at the place where they may have an effect on people or the environment. Both types of measurement complement each other and are essential for the implementation of air quality legislation, particularly, in compliance with emission and ambient air quality limit values. Presented here are similar accounts of measurement principles and also contains as an Appendix a list of suitability-tested measuring devices which is based on information provided by the manufacturers. In addition, the guide of ambient air quality control contains further information on discontinuous measurement methods, on measurement planning and on the assessment of ambient air quality data. (orig./SR)

  9. Investigation of Diesel Exhaust Gas Toxicity on Transient Modes

    Directory of Open Access Journals (Sweden)

    Ivashchenko Nikolay Antonovich

    2014-12-01

    Full Text Available Currently, the generation of heat engines and their control systems are based on ecological indices such as the toxicity of the fulfilled gases. When designing motors, software packages are widely used. These software packages provide the ability to calculate the workflow of engine at steady-state conditions. The definition of indicators emissions is a difficult task. The distribution statistics of the modes shows that the engines of the transport units work on unsteady modes most of the time. The calculation of toxicity indicators is even less developed. In this article experimental and numeric study of the diesel engine with turbocharger exhaust toxicity was considered. As a result of the experimental study, which was conducted with single-cylinder diesel engine compartment simulated work on the transient state, working process characteristics of a diesel engine were obtained, including carbon and nitrogen oxides concentrations. Functional dependencies of concentrations of toxic exhaust components, such as carbon and nitrogen oxides, on excess air ratio and exhaust temperature were obtained. Diesel engine transient processes were simulated using developed mathematical dynamic model of combined engine in locomotive power plant with a change in control signal (position of locomotive driver’s controller and external influence signal (resistance moment. The analysis of exhaust gas toxicity was conducted.

  10. Naphthalene toxicity and antioxidant nutrients.

    Science.gov (United States)

    Stohs, Sidney J; Ohia, Sunny; Bagchi, Debasis

    2002-10-30

    Naphthalene is a bicyclic aromatic compound that has wide industrial and commercial applications. It is used as the starting material for the synthesis of other compounds, as a moth repellent, soil fumigant and lavatory deodorant. Most exposure occurs through low dose chronic inhalation, dermal contact or ingestion through the food chain. The lungs and eyes appear to be most susceptible to toxicity, although biochemical markers of toxicity can be demonstrated in other tissues, such as the kidney, brain and liver. In addition to lens opacification (cataracts) and histological changes associated with pneumotoxicity, other biomarkers of toxic effects include glutathione depletion, lipid peroxidation, DNA fragmentation and the production of the active oxygen species as superoxide anion and hydroxyl radical. In addition, the urinary excretion of lipid metabolites occurs. A role for the tumor suppressor gene p53 has been demonstrated. Toxic manifestations of naphthalene are associated with its oxidative metabolism to various products including quinones. The ability to protect against the toxic effects of naphthalene by using various antioxidants and free radical scavengers has been demonstrated. Studies have been conducted with vitamin E, vitamin E succinate, melatonin, curcumin, various L-cysteine prodrugs, several aldose reductase inhibitors and spin-trapping agents. The ability to prevent the toxic manifestations of naphthalene is dependent on the pharmacokinetic properties of the agents, which have been studied. The appropriate selection of chemoprotectants can be useful in preventing naphthalene toxicity.

  11. Laser dye toxicity, hazards, and recommended controls

    Energy Technology Data Exchange (ETDEWEB)

    Mosovsky, J.A.

    1983-05-06

    Laser dyes are complex fluorescent organic compounds which, when in solution with organic solvents, form a lasing medium. The wavelength of a dye laser's output beam can vary with different dyes, concentrations, and solvents, giving it a tunable feature capable of emitting ultraviolet, visible, or infrared radiation. Toxicity information on the approximately 100 commercially available laser dyes is very scarce. Limited animal experimentation has been performed with only a few dyes. This paper summarizes what is known about laser dye toxicity, and offers recommendations for controlling dye hazards. The laser dyes investigated have been categorized according to their central chemical structures. These include the xanthenes (rhodamines and fluoresceins), polymethines (cyanines and carbocyanines), coumarins, and stilbenes. A few other miscellaneous dyes that do not fall into one of these categories have also been investigated. Prepared laser dye solutions usually contain very small quantities of dye--typical dye concentrations are 10/sup -2/ to 10/sup -5/ molar. For this reason, the solvent in which the dye is dissolved plays an important role when defining potential hazards. Practically all the solvents used are flammable and toxic by inhalation and skin absorption, and therefore must be controlled properly.

  12. Molecular toxicity mechanism of nanosilver

    Directory of Open Access Journals (Sweden)

    Danielle McShan

    2014-03-01

    Full Text Available Silver is an ancient antibiotic that has found many new uses due to its unique properties on the nanoscale. Due to its presence in many consumer products, the toxicity of nanosilver has become a hot topic. This review summarizes recent advances, particularly the molecular mechanism of nanosilver toxicity. The surface of nanosilver can easily be oxidized by O2 and other molecules in the environmental and biological systems leading to the release of Ag+, a known toxic ion. Therefore, nanosilver toxicity is closely related to the release of Ag+. In fact, it is difficult to determine what portion of the toxicity is from the nano-form and what is from the ionic form. The surface oxidation rate is closely related to the nanosilver surface coating, coexisting molecules, especially thiol-containing compounds, lighting conditions, and the interaction of nanosilver with nucleic acids, lipid molecules, and proteins in a biological system. Nanosilver has been shown to penetrate the cell and become internalized. Thus, nanosilver often acts as a source of Ag+ inside the cell. One of the main mechanisms of toxicity is that it causes oxidative stress through the generation of reactive oxygen species and causes damage to cellular components including DNA damage, activation of antioxidant enzymes, depletion of antioxidant molecules (e.g., glutathione, binding and disabling of proteins, and damage to the cell membrane. Several major questions remain to be answered: (1 the toxic contribution from the ionic form versus the nano-form; (2 key enzymes and signaling pathways responsible for the toxicity; and (3 effect of coexisting molecules on the toxicity and its relationship to surface coating.

  13. Clean air Hamilton 2001 progress report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-05-01

    This community initiative called Clean Air Hamilton was established to improve air quality in Hamilton, Ontario. It has been mandated to annually report on progress and provide advice with regard to current air quality issues. The quality of life of residents is improved as a result of the work performed by Clean Air Hamilton, and it also enhances Hamilton's image. Numerous inquiries have been received from City officials in several municipalities such as Toronto, Kitchener-Waterloo and Windsor as a testament to the success of the initiative. Financial support is received from all levels of government. The funding received from the Council has helped in attracting additional donations in support of this initiative. Clean Air Hamilton was involved in one capacity or another in research, emissions reduction projects and public awareness campaigns during 2001, and its contributions were valued at approximately 500,000 dollars. The City of Hamilton was awarded the United Nations for Human Settlements award as a result of Clean Air Hamilton's community process in local air quality improvement. In addition, the City received the Dubai International Award for Best Practices in Improving the Living Environment. Clean Air Hamilton is ready to move to the next phase, which requires moving current structures that supplements voluntary commitments with committed funding from key stakeholders. Since June 1996, the advisory level of 32 on the Air Pollution Index has not been reached, and rarely goes over 20. Throughout the 1990s, levels of toxics have decreased significantly. A three-year self-sustaining program should be developed and funding sought for those initiatives, discussions should be facilitated among industrial stakeholders when they address air quality issues, and research should continue to be supported and advice on current air quality issues be provided to City Council. 1 fig.

  14. Methylmercury toxicity and functional programming

    DEFF Research Database (Denmark)

    Grandjean, Philippe

    2007-01-01

    PURPOSE: Adverse health effects of developmental toxicants may induce abnormal functional programming that leads to lasting functional deficits. This notion is considered from epidemiological evidence using developmental methylmercury neurotoxicity as an example. MOST IMPORTANT FINDINGS...... of certain brain functions, thereby causing confounding bias. The functional deficits caused by prenatal methylmercury exposure appear to be permanent, and their extent may depend on the joint effect of toxicants and nutrients. PRINCIPAL CONCLUSIONS: The lasting functional changes caused...... by neurodevelopmental methylmercury toxicity fit into the pattern of functional programming, with effects opposite to those linked to beneficial stimuli....

  15. Toxicity of Uranium Adsorbent Materials using the Microtox Toxicity Test

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jiyeon [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Jeters, Robert T. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Gill, Gary A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kuo, Li-Jung [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Bonheyo, George T. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-10-01

    The Marine Sciences Laboratory at the Pacific Northwest National Laboratory evaluated the toxicity of a diverse range of natural and synthetic materials used to extract uranium from seawater. The uranium adsorbent materials are being developed as part of the U. S. Department of Energy, Office of Nuclear Energy, Fuel Resources Program. The goal of this effort was to identify whether deployment of a farm of these materials into the marine environment would have any toxic effects on marine organisms.

  16. Toxicity of staphylococcal toxic shock syndrome toxin 1 in rabbits.

    OpenAIRE

    de Azavedo, J C; Arbuthnott, J P

    1984-01-01

    Strains of Staphylococcus aureus associated with toxic shock syndrome produce toxic shock syndrome toxin 1 (TSST 1), which is lethal to conventional rabbits and acts synergistically with gram-negative lipopolysaccharide. The lethal effect of TSST 1 was examined in specific-pathogen-free rabbits on the basis that these rabbits, being less colonized by gram-negative bacteria, would be less susceptible than conventional animals. Although there was no significant difference in mortality between s...

  17. Effects of air pollution on human health and practical measures for prevention in Iran

    OpenAIRE

    Adel Ghorani-Azam; Bamdad Riahi-Zanjani; Mahdi Balali-Mood

    2016-01-01

    Air pollution is a major concern of new civilized world, which has a serious toxicological impact on human health and the environment. It has a number of different emission sources, but motor vehicles and industrial processes contribute the major part of air pollution. According to the World Health Organization, six major air pollutants include particle pollution, ground-level ozone, carbon monoxide, sulfur oxides, nitrogen oxides, and lead. Long and short term exposure to air suspended toxic...

  18. Multidrug toxicity involving sumatriptan.

    Science.gov (United States)

    Knittel, Jessica L; Vorce, Shawn P; Levine, Barry; Hughes, Rhome L; Bosy, Thomas Z

    2015-01-01

    A multidrug fatality involving sumatriptan is reported. Sumatriptan is a tryptamine derivative that acts at 5-HT(1B/1D) receptors and is used for the treatment of migraines. The decedent was a 21-year-old white female found dead in bed by her spouse. No signs of physical trauma were observed and a large number of prescription medications were discovered at the scene. Toxicological analysis of the central blood revealed sumatriptan at a concentration of 1.03 mg/L. Following therapeutic dosing guidelines, sumatriptan concentrations do not exceed 0.095 mg/L. Sumatriptan was isolated by solid-phase extraction and analyzed using liquid chromatography-tandem mass spectrometry in multiple reaction monitoring mode. A tissue distribution study was completed with the following concentrations measured: 0.61 mg/L in femoral blood, 0.56 mg/L in iliac blood, 5.01 mg/L in urine, 0.51 mg/kg in liver, 3.66 mg/kg in kidney, 0.09 mg/kg in heart, 0.32 mg/kg in spleen, 0.01 mg/kg in brain, 15.99 mg/kg in lung and 78.54 mg/45 mL in the stomach contents. Carisoprodol, meprobamate, fluoxetine, doxylamine, orphenadrine, dextromethorphan and hydroxyzine were also present in the blood at the following concentrations: 3.35, 2.36, 0.63, 0.19, 0.06, 0.55 and 0.16 mg/L. The medical examiner ruled the cause of death as acute mixed drug toxicity and the manner of death as accident.

  19. Toxicity Data to Determine Refrigerant Concentration Limits

    Energy Technology Data Exchange (ETDEWEB)

    Calm, James M.

    2000-09-30

    This report reviews toxicity data, identifies sources for them, and presents resulting exposure limits for refrigerants for consideration by qualified parties in developing safety guides, standards, codes, and regulations. It outlines a method to calculate an acute toxicity exposure limit (ATEL) and from it a recommended refrigerant concentration limit (RCL) for emergency exposures. The report focuses on acute toxicity with particular attention to lethality, cardiac sensitization, anesthetic and central nervous system effects, and other escape-impairing effects. It addresses R-11, R-12, R-22, R-23, R-113, R-114, R-116, R-123, R-124, R-125, R-134, R-134a, R-E134, R-141b, R-142b, R-143a, R-152a, R-218, R-227ea, R-236fa, R-245ca, R-245fa, R-290, R-500, R-502, R-600a, R-717, and R-744. It summarizes additional data for R-14, R-115, R-170 (ethane), R-C318, R-600 (n-butane), and R-1270 (propylene) to enable calculation of limits for blends incorporating them. The report summarizes the data a nd related safety information, including classifications and flammability data. It also presents a series of tables with proposed ATEL and RCL concentrations-in dimensionless form and the latter also in both metric (SI) and inch-pound (IP) units of measure-for both the cited refrigerants and 66 zerotropic and azeotropic blends. They include common refrigerants, such as R-404A, R-407C, R-410A, and R-507A, as well as others in commercial or developmental status. Appendices provide profiles for the cited single-compound refrigerants and for R-500 and R-502 as well as narrative toxicity summaries for common refrigerants. The report includes an extensive set of references.

  20. Novel Molecular Strategies Against Sulfur Mustard Toxicity

    Directory of Open Access Journals (Sweden)

    Zeki Ilker Kunak

    2012-04-01

    Full Text Available Among the available chemical warfare agents, sulfur mustard (SM, also known as mustard gas, has been widely used chemical weapon. In our laboratory, we have shown that, acute toxicity of SM is related to reactive oxygen and nitrogen species, DNA damage, poly(ADP-ribose polymerase activation and energy depletion within the affected cell. In spite of the knowledge about acute SM-induced cellular toxicity, unfortunately, it is not clear how mustard gas causes severe multi-organ damage years after even a single exposure. A variety of treatment modalities including antioxidants, anti-inflammatory drugs and others have resulted no promising results. We, therefore, made an attempt whether epigenetic aberrations may contribute to pathogenesis of mustard poisoning. The term epigenetic describes the study of inheritable alterations in gene expression that occur in the absence of changes in genome sequence. Therefore, epigenetic gene regulation requires molecular mechanisms that encode information in addition to the DNA base sequence and can be propagated through mitosis and meiosis. Our current understanding of epigenetic regulation of gene expression involves basically two classes of molecular mechanisms: histone modifications and DNA methylation. Preliminary evidence obtained from our laboratory reveals that exposure to mustards may not only cause nitro-oxidative stress and DNA (genetic damage, but epigenetic perturbations as well. Epigenetic therapy is a new and rapidly developing field in pharmacology. Epigenetic drugs alone or in combination with conventional drugs may prove to be a significant advance over the conventional drugs used to treat both acute and delayed SM toxicity. Future studies are urgently needed to clarify the mechanism of delayed SM-induced toxicity and novel treatment modalities. [TAF Prev Med Bull 2012; 11(2.000: 231-236

  1. Air filtration and indoor air quality

    DEFF Research Database (Denmark)

    Bekö, Gabriel

    2006-01-01

    decent ventilation and air cleaning/air filtration, high indoor air quality cannot be accomplished. The need for effective air filtration has increased with increasing evidence on the hazardous effects of fine particles. Moreover, the air contains gaseous pollutants, removal of which requires various air....... These contradictions should motivate manufacturers and researchers to develop new efficient filtration techniques and/or improve the existing ones. Development of low polluting filtration techniques, which are at the same time easy and inexpensive to maintain is the way forward in the future....

  2. Air Conditioning and Heating Technology--II.

    Science.gov (United States)

    Gattone, Felix

    Twenty-eight chapters and numerous drawings provide information for instructors and students of air conditioning and heating technology. Chapter 1 lists the occupational opportunities in the field. Chapter 2 covers the background or development of the industry of air conditioning and heating technology. Chapter 3 includes some of the principle…

  3. Non-Toxic HAN Monopropellant Propulsion Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Non-toxic monopropellants have been developed that provide better performance than toxic hydrazine. Formulations based on hydroxylammonium nitrate (HAN) have...

  4. Air Leakage and Air Transfer Between Garage and Living Space

    Energy Technology Data Exchange (ETDEWEB)

    Rudd, Armin [Building Science Corporation, Westford, MA (United States)

    2014-09-01

    This research project focused on evaluation of air transfer between the garage and living space in a single-family detached home constructed by a production homebuilder in compliance with the 2009 International Residential Code and the 2009 International Energy Conservation Code. The project gathered important information about the performance of whole-building ventilation systems and garage ventilation systems as they relate to minimizing flow of contaminated air from garage to living space. A series of 25 multi-point fan pressurization tests and additional zone pressure diagnostic testing characterized the garage and house air leakage, the garage-to-house air leakage, and garage and house pressure relationships to each other and to outdoors using automated fan pressurization and pressure monitoring techniques. While the relative characteristics of this house may not represent the entire population of new construction configurations and air tightness levels (house and garage) throughout the country, the technical approach was conservative and should reasonably extend the usefulness of the results to a large spectrum of house configurations from this set of parametric tests in this one house. Based on the results of this testing, the two-step garage-to-house air leakage test protocol described above is recommended where whole-house exhaust ventilation is employed.

  5. Comparative toxicities of oxygen, ozone, chlorine dioxide, and chlorine bleaching filtrates - microtox toxicities of raw and processed filtrates

    Energy Technology Data Exchange (ETDEWEB)

    Ard, T.A.; McDonough, T.J.

    1995-12-31

    It has claimed that effluents from the bleaching of kraft pulp with chlorine and its compounds have deleterious effects on the aquatic environment. It has been further suggested that bleaching without the use of chlorine or its compounds will produce innocuous effluents. To obtain information on the validity of these claims, we have conducted a laboratory study of the toxicity of filtrates from chlorine-based and nonchlorine bleaching processes. We have also examined two related issues. The first is whether any toxicants generated during bleaching are rendered harmless (by neutralization, storage, and biological treatment) before being discharged to the environment. The second related issue is whether any toxicity observed in mill effluents actually originates in the bleaching process, as opposed to being due to raw material components or compounds formed during the pulping step that precedes bleaching. Several conclusions were drawn from this study. (1) There is a background level of toxicity which originates in the oxygen stage, process steps prior to bleaching, or in the wood raw material. It is decreased by neutralization and storage, but residual toxicity may still be detected after two weeks. (2) If the sum of the first and second stage toxicities is taken as an indicator of overall toxicity, the untreated filtrates may be ranked as follows: Control (Background) > D(EO) > Z(EO) > C(EO). However, these toxicities are of no importance in regard to environmental effects because of their ephemeral nature and the likelihood of their being reduced or eliminated prior to effluent discharge. Evidence for this statement is the ease with which all except the C(EO) were detoxified by neutralization and storage. (3) After neutralization and storage for two weeks at room temperature the ranking of toxicities becomes: C(EO) > D(EO) > Z(EO) > Background. The last three are similar in magnitude.

  6. Environmental Health Risks and Housing Values: Evidence from 1,600 Toxic Plant Openings and Closings†

    Science.gov (United States)

    Currie, Janet; Davis, Lucas; Greenstone, Michael

    2016-01-01

    Regulatory oversight of toxic emissions from industrial plants and understanding about these emissions’ impacts are in their infancy. Applying a research design based on the openings and closings of 1,600 industrial plants to rich data on housing markets and infant health, we find that: toxic air emissions affect air quality only within 1 mile of the plant; plant openings lead to 11 percent declines in housing values within 0.5 mile or a loss of about $4.25 million for these households; and a plant’s operation is associated with a roughly 3 percent increase in the probability of low birthweight within 1 mile. PMID:27134284

  7. 40 CFR 68.65 - Process safety information.

    Science.gov (United States)

    2010-07-01

    ... consist of at least the following: (1) Toxicity information; (2) Permissible exposure limits; (3) Physical... deviations. (2) Where the original technical information no longer exists, such information may be...

  8. Guide to Air Cleaners in the Home

    Science.gov (United States)

    ... Ozone Generators that are Sold as Air Cleaners webpage for more information. The chart below provides a ... always safe and effective in removing pollutants. By design, they produce ozone, a lung irritant. In addition ...

  9. Air pollution

    Energy Technology Data Exchange (ETDEWEB)

    1974-12-01

    Air pollution conditions in Iwakuni city were monitored at 9 monitoring stations, and 21 locations where sulfur oxides were measured by the lead peroxide candle method, and 13 locations where particulates concentrations were determined by the deposit cage method. The average SO/sub x/ concentrations in 1973 measured by the lead peroxide candle method ranged from 0.17 mg sulfur trioxide/day/100 sq cm at the Miso Office to 0.58 mg SO/sub 3//day/100 sq cm at Mitsui Sekiyu Shataku. The average SO/sub x/ concentrations measured by the conductivity method ranged from 0.021 ppM at Kazuki Kominkan to 0.037 ppM at the Higashi Fire Department. Only 58% of a total of 264 measurement days gave hourly average concentrations below the environmental standard of 0.04 ppM at the Higashi Fire Deparment. The average airborne particulate concentrations ranged from 0.050 mg/cu m at Totsu Kominkan to 0.056 mg/cu at the Higashi Fire Department. The average nitrogen oxides concentrations measured by the Saltzman method ranged from 0.007 ppM to 0.061 ppM. The average oxidant concentrations at the Iwakuni Municipal Office and Kazuki Kominkan were 0.028 ppM and 0.037 ppM, respectively.

  10. Low-Toxicity PMR Polyimide

    Science.gov (United States)

    Pater, Ruth H.; Ely, Robert M.; Stanfield, Clarence E.; Dickerson, George E.; Snoha, John J.; Srinivasan, Krishna; Hou, Tan

    1994-01-01

    New low-toxicity PMR system developed and designated LaRC-RP46. Exhibits better processability, toughness, and thermo-oxidative stability than does PMR-15. Polyimide inexpensive and readily processed into high-quality graphite-fiber-reinforced composite. Used as high-performance, high-temperature-resistant adhesive, molding, composite, film, and coating material where low toxicity desired characteristic. Significantly extends applications of PMR-type polyimides.

  11. Air Cleaning Devices for HVAC Supply Systems in Schools. Technical Bulletin.

    Science.gov (United States)

    Wheeler, Arthur E.

    Guidelines for maintaining indoor air quality in schools with HVAC air cleaning systems are provided in this document. Information is offered on the importance of air cleaning, sources of air contaminants and indoor pollutants, types of air cleaners and particulate filters used in central HVAC systems, vapor and gas removal, and performance…

  12. Ocular toxicity of targeted therapies.

    Science.gov (United States)

    Renouf, Daniel J; Velazquez-Martin, Juan P; Simpson, Rand; Siu, Lillian L; Bedard, Philippe L

    2012-09-10

    Molecularly targeted agents are commonly used in oncology practice, and many new targeted agents are currently being tested in clinical trials. Although these agents are thought to be more specific and less toxic then traditional cytotoxic chemotherapy, they are associated with a variety of toxicities, including ocular toxicity. Many of the molecules targeted by anticancer agents are also expressed in ocular tissues. We reviewed the literature for described ocular toxicities associated with both approved and investigational molecularly targeted agents. Ocular toxicity has been described with numerous approved targeted agents and also seems to be associated with several classes of agents currently being tested in early-phase clinical trials. We discuss the proposed pathogenesis, monitoring guidelines, and management recommendations. It is important for oncologists to be aware of the potential for ocular toxicity, with prompt recognition of symptoms that require referral to an ophthalmologist. Ongoing collaboration between oncologists and ocular disease specialists is critical as the use of molecularly targeted agents continues to expand and novel targeted drug combinations are developed.

  13. Air Quality Assessment Using Interpolation Technique

    Directory of Open Access Journals (Sweden)

    Awkash Kumar

    2016-07-01

    Full Text Available Air pollution is increasing rapidly in almost all cities around the world due to increase in population. Mumbai city in India is one of the mega cities where air quality is deteriorating at a very rapid rate. Air quality monitoring stations have been installed in the city to regulate air pollution control strategies to reduce the air pollution level. In this paper, air quality assessment has been carried out over the sample region using interpolation techniques. The technique Inverse Distance Weighting (IDW of Geographical Information System (GIS has been used to perform interpolation with the help of concentration data on air quality at three locations of Mumbai for the year 2008. The classification was done for the spatial and temporal variation in air quality levels for Mumbai region. The seasonal and annual variations of air quality levels for SO2, NOx and SPM (Suspended Particulate Matter have been focused in this study. Results show that SPM concentration always exceeded the permissible limit of National Ambient Air Quality Standard. Also, seasonal trends of pollutant SPM was low in monsoon due rain fall. The finding of this study will help to formulate control strategies for rational management of air pollution and can be used for many other regions.

  14. HEPA air filter (image)

    Science.gov (United States)

    ... pet dander and other irritating allergens from the air. Along with other methods to reduce allergens, such ... controlling the amount of allergens circulating in the air. HEPA filters can be found in most air ...

  15. GSPEL - Air Filtration Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Evaluation capabilities for air filtration devicesThe Air Filtration Lab provides testing of air filtration devices to demonstrate and validate new or legacy system...

  16. Lead (Pb) Air Pollution

    Science.gov (United States)

    ... States Environmental Protection Agency Search Search Lead (Pb) Air Pollution Share Facebook Twitter Google+ Pinterest Contact Us As ... and protect aquatic and terrestrial ecosystems. Lead (Pb) Air Pollution Lead Air Pollution Basics How does lead get ...

  17. FDA toxicity databases and real-time data entry.

    Science.gov (United States)

    Arvidson, Kirk B

    2008-11-15

    Structure-searchable electronic databases are valuable new tools that are assisting the FDA in its mission to promptly and efficiently review incoming submissions for regulatory approval of new food additives and food contact substances. The Center for Food Safety and Applied Nutrition's Office of Food Additive Safety (CFSAN/OFAS), in collaboration with Leadscope, Inc., is consolidating genetic toxicity data submitted in food additive petitions from the 1960s to the present day. The Center for Drug Evaluation and Research, Office of Pharmaceutical Science's Informatics and Computational Safety Analysis Staff (CDER/OPS/ICSAS) is separately gathering similar information from their submissions. Presently, these data are distributed in various locations such as paper files, microfiche, and non-standardized toxicology memoranda. The organization of the data into a consistent, searchable format will reduce paperwork, expedite the toxicology review process, and provide valuable information to industry that is currently available only to the FDA. Furthermore, by combining chemical structures with genetic toxicity information, biologically active moieties can be identified and used to develop quantitative structure-activity relationship (QSAR) modeling and testing guidelines. Additionally, chemicals devoid of toxicity data can be compared to known structures, allowing for improved safety review through the identification and analysis of structural analogs. Four database frameworks have been created: bacterial mutagenesis, in vitro chromosome aberration, in vitro mammalian mutagenesis, and in vivo micronucleus. Controlled vocabularies for these databases have been established. The four separate genetic toxicity databases are compiled into a single, structurally-searchable database for easy accessibility of the toxicity information. Beyond the genetic toxicity databases described here, additional databases for subchronic, chronic, and teratogenicity studies have been prepared.

  18. AirPEx: Air Pollution Exposure Model

    OpenAIRE

    Freijer JI; Bloemen HJTh; de Loos S; Marra M; Rombout PJA; Steentjes GM; Veen MP van; LBO

    1997-01-01

    Analysis of inhalatory exposure to air pollution is an important area of investigation when assessing the risks of air pollution for human health. Inhalatory exposure research focuses on the exposure of humans to air pollutants and the entry of these pollutants into the human respiratory tract. The principal grounds for studying the inhalatory exposure of humans to air pollutants are formed by the need for realistic exposure/dose estimates to evaluate the health effects of these pollutants. T...

  19. Comprehensive assessment of toxic emissions from coal-fired power plants

    Energy Technology Data Exchange (ETDEWEB)

    Brown, T D; Schmidt, C E [USDOE Pittsburgh Energy Technology Center, PA (United States); Radziwon, A S [Burns and Roe Services Corp., Pittsburgh, PA (United States)

    1991-01-01

    The Pittsburgh Energy Technology Center (PETC) of the US Department of Energy (DOE) has two current investigations, initiated before passage of the Clean Air Act Amendment (CAAA), that will determine the air toxic emissions from coal-fired electric utilities. DOE has contracted with Battelle Memorial Institute and Radian corporation to conduct studies focusing on the potential air toxics, both organic and inorganic, associated with different size fractions of fine particulate matter emitted from power plant stacks. Table 2 indicates the selected analytes to be investigated during these studies. PETC is also developing guidance on the monitoring of Hazardous Air Pollutants (HAPS) to be incorporated in the Environmental Monitoring plans for the demonstration projects in its Clean Coal Technology Program.

  20. AirPEx: Air Pollution Exposure Model

    NARCIS (Netherlands)

    Freijer JI; Bloemen HJTh; Loos S de; Marra M; Rombout PJA; Steentjes GM; Veen MP van; LBO

    1997-01-01

    Analysis of inhalatory exposure to air pollution is an important area of investigation when assessing the risks of air pollution for human health. Inhalatory exposure research focuses on the exposure of humans to air pollutants and the entry of these pollutants into the human respiratory tract. The

  1. Toxic chemical considerations for tank farm releases

    Energy Technology Data Exchange (ETDEWEB)

    Van Keuren, J.C.; Davis, J.S., Westinghouse Hanford

    1996-08-01

    This topical report contains technical information used to determine the accident consequences of releases of toxic chemical and gases for the Tank Farm Final Safety Analysis report (FSAR).It does not provide results for specific accident scenarios but does provide information for use in those calculations including chemicals to be considered, chemical concentrations, chemical limits and a method of summing the fractional contributions of each chemical. Tank farm composites evaluated were liquids and solids for double shell tanks, single shell tanks, all solids,all liquids, headspace gases, and 241-C-106 solids. Emergency response planning guidelines (ERPGs) were used as the limits.Where ERPGs were not available for the chemicals of interest, surrogate ERPGs were developed. Revision 2 includes updated sample data, an executive summary, and some editorial revisions.

  2. Functional toxicology: tools to advance the future of toxicity testing

    Directory of Open Access Journals (Sweden)

    Brandon David Gaytán

    2014-05-01

    Full Text Available The increased presence of chemical contaminants in the environment is an undeniable concern to human health and ecosystems. Historically, by relying heavily upon costly and laborious animal-based toxicity assays, the field of toxicology has often neglected examinations of the cellular and molecular mechanisms of toxicity for the majority of compounds – information that, if available, would strengthen risk assessment analyses. Functional toxicology, where cells or organisms with gene deletions or depleted proteins are used to assess genetic requirements for chemical tolerance, can advance the field of toxicity testing by contributing data regarding chemical mechanisms of toxicity. Functional toxicology can be accomplished using available genetic tools in yeasts, other fungi and bacteria, and eukaryotes of increased complexity, including zebrafish, fruit flies, rodents, and human cell lines. Underscored is the value of using less complex systems such as yeasts to direct further studies in more complex systems such as human cell lines. Functional techniques can yield (1 novel insights into chemical toxicity; (2 pathways and mechanisms deserving of further study; and (3 candidate human toxicant susceptibility or resistance genes.

  3. Predicting toxicity of aromatic ternary mixtures to algae

    Institute of Scientific and Technical Information of China (English)

    LU GuangHua; WANG Chao; WANG PeiFang; YANG ChengZhi

    2009-01-01

    Aquatic ecosystems are often polluted with more than one type of contaminant, and information on the combined toxic effects of mixed pollutants on aquatic organisms is scarce at present. Acute toxicity of aromatic compounds and their ternary mixtures to the alga (Scenedesmus obliquus) was determined by the algae growth inhibition test. The median effective concentration (EC_(50)) value for a single aromatic compound and EC_(50mix) values for mixtures were obtained, the logarithm of n-octanol/water partition coefficient (logP_(mix)) and the frontier orbital energy gap (△E_(mix) for mixtures were calculated. Based on the quantitative structure-activity relationship model for single chemical toxicity log(1/EC_(50)) =0.426logP-1.150△E+12.61 (n=15, R~2=0.917 and Q~2=0.878), the following two-descriptor model was developed for the ternary mixture toxicity of aromatic compounds: log(1/EC_(50mix))=O.68210gP_(mix)-O.367△E_(mix)+ 4.971 (n=44, R~2-0.869 and Q~2=0.843). This model can be used to predict the combined toxicity of mixtures containing toxicants with different mechanisms of action.

  4. Information and Informality

    DEFF Research Database (Denmark)

    Larsson, Magnus; Segerstéen, Solveig; Svensson, Cathrin

    2011-01-01

    leaders were thus seen to function on the level of the organization as a whole, and in cooperation with formal leaders. Drawing on existing theory of leadership in creative and professional contexts, this cooperation can be specified to concern task structuring. The informal leaders in our study......The article presents an empirical study of informal leadership in an international high-tech company. The empirical work consisted of qualitative observation and shadowing of managers in the company, and a total of 14 interviews. The transcribed fieldnotes and audio recordings of observations...... and interviews were analyzed thematically, resulting in three central themes: informality, information based authority, and information brokering. The general informal character of interactions at work included a network based information dissemination. In these networks, persons were percieved as informal...

  5. Reproductive and developmental toxicity of phthalates.

    Science.gov (United States)

    Lyche, Jan L; Gutleb, Arno C; Bergman, Ake; Eriksen, Gunnar S; Murk, AlberTinka J; Ropstad, Erik; Saunders, Margaret; Skaare, Janneche U

    2009-04-01

    scarce. Therefore, future research needs to focus on developmental and reproductive endpoints in humans. It should be noted that phthalates occur in mixtures but most toxicological information is based on single compounds. Thus, it is concluded that it is important to improve the knowledge of toxic interactions among the different chemicals and to develop measures for combined exposure to various groups of phthalates.

  6. The toxicity and pathology of selected dietary herbal medicines.

    Science.gov (United States)

    Dunnick, June K; Nyska, Abraham

    2013-02-01

    Toxicity studies were conducted by the National Toxicology Program (NTP) to provide information on the potential for toxicity from long-term use of commonly used herbal medicines. Here, we review the findings from these NTP toxicology/carcinogenesis 2-year rodent studies of 7 commonly used herbs. In these studies, the individual herb or herbal product was administered to F344/N rats and B6C3F1 mice by oral administration for up to 2 years. The spectrum of carcinogenic responses ranged from no or equivocal evidence for carcinogenic activity (ginseng, milk thistle, and turmeric oleoresin) to a liver tumor response (ginkgo, goldenseal, kava), thyroid tumor response (ginkgo), or an intestinal tumor response (Aloe vera whole leaf nondecolorized extract). Different mechanisms may be involved in the occurrence of liver (ginkgo, goldenseal, and kava kava) and gastrointestinal toxicity (turmeric oleoresin and Aloe vera whole leaf nondecolorized extract), while the toxic lesion is the same. The results from these hazard identification toxicity/carcinogenesis studies along with those from ongoing National Institute of Health clinical trials of herbal medicines provide more complete information on the risks and benefits from herbal medicine use in the general population.

  7. Accelerated Hematopoietic Toxicity by High Energy 56Fe Radiation

    Science.gov (United States)

    Datta, Kamal; Suman, Shubhankar; Trani, Daniela; Doiron, Kathryn; Rotolo, Jimmy A.; Kallakury, Bhaskar V. S.; Kolesnick, Richard; Cole, Michael F.; Fornace, Albert J.

    2013-01-01

    Purpose There is little information on the relative toxicity of highly charged (Z) high-energy (HZE) radiation in animal models compared to γ or x-rays, and the general assumption based on in vitro studies has been that acute toxicity is substantially greater. Methods C57BL/6J mice were irradiated with 56Fe ions (1 GeV/nucleon), and acute (within 30 d) toxicity compared to that of γ rays or protons (1 GeV). To assess relative hematopoietic and gastrointestinal toxicity, the effects of 56Fe ions were compared to γ rays using complete blood count (CBC), bone marrow granulocyte-macrophage colony forming unit (GM-CFU), terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay for apoptosis in bone marrow, and intestinal crypt survival. Results Although onset was more rapid, 56Fe ions were only slightly more toxic than γ rays or protons with lethal dose (LD)50/30 (a radiation dose at which 50% lethality occurs at 30-day) values of 5.8, 7.25, and 6.8 Gy respectively with relative biologic effectiveness for 56Fe ions of 1.25 and 1.06 for protons. Conclusions 56Fe radiation caused accelerated and more severe hematopoietic toxicity. Early mortality correlated with more profound leukopenia and subsequent sepsis. Results indicate that there is selective enhanced toxicity to bone marrow progenitor cells, which are typically resistant to γ rays, and bone marrow stem cells, because intestinal crypt cells did not show increased HZE toxicity. PMID:22077279

  8. THE ART OF DATA MINING THE MINEFIELDS OF TOXICITY ...

    Science.gov (United States)

    Toxicity databases have a special role in predictive toxicology, providing ready access to historical information throughout the workflow of discovery, development, and product safety processes in drug development as well as in review by regulatory agencies. To provide accurate information within a hypothesesbuilding environment, the content of the databases needs to be rigorously modeled using standards and controlled vocabulary. The utilitarian purposes of databases widely vary, ranging from a source for (Q)SAR datasets for modelers to a basis for

  9. Unitary and room air-conditioners

    Energy Technology Data Exchange (ETDEWEB)

    Christian, J.E.

    1977-09-01

    The scope of this technology evaluation on room and unitary air conditioners covers the initial investment and performance characteristics needed for estimating the operating cost of air conditioners installed in an ICES community. Cooling capacities of commercially available room air conditioners range from 4000 Btu/h to 36,000 Btu/h; unitary air conditioners cover a range from 6000 Btu/h to 135,000 Btu/h. The information presented is in a form useful to both the computer programmer in the construction of a computer simulation of the packaged air-conditioner's performance and to the design engineer, interested in selecting a suitably sized and designed packaged air conditioner.

  10. The cellular toxicity of aluminium.

    Science.gov (United States)

    Exley, C; Birchall, J D

    1992-11-07

    Aluminium is a serious environmental toxicant and is inimical to biota. Omnipresent, it is linked with a number of disorders in man including Alzheimer's disease, Parkinson's dementia and osteomalacia. Evidence supporting aluminium as an aetiological agent in such disorders is not conclusive and suffers principally from a lack of consensus with respect to aluminium's toxic mode of action. Obligatory to the elucidation of toxic mechanisms is an understanding of the biological availability of aluminium. This describes the fate of and response to aluminium in any biological system and is thus an important influence of the toxicity of aluminium. A general theme in much aluminium toxicity is an accelerated cell death. Herein mechanisms are described to account for cell death from both acute and chronic aluminium challenges. Aluminium associations with both extracellular surfaces and intracellular ligands are implicated. The cellular response to aluminium is found to be biphasic having both stimulatory and inhibitory components. In either case the disruption of second messenger systems is observed and GTPase cycles are potential target sites. Specific ligands for aluminium at these sites are unknown though are likely to be proteins upon which oxygen-based functional groups are orientated to give exceptionally strong binding with the free aluminium ion.

  11. 40 CFR 52.1778 - Significant deterioration of air quality.

    Science.gov (United States)

    2010-07-01

    ... quality. 52.1778 Section 52.1778 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a)-(b) (c) All applications and other information required pursuant... Air Quality, 1641 Mail Service Center, Raleigh, North Carolina 27699-1641 or local agencies,...

  12. 40 CFR 52.60 - Significant deterioration of air quality.

    Science.gov (United States)

    2010-07-01

    ... quality. 52.60 Section 52.60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... deterioration of air quality. (a) All applications and other information required pursuant to § 52.21 from... “Guideline on Air Quality Models (Revised)” or other models approved by EPA....

  13. 40 CFR 52.2131 - Significant deterioration of air quality.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Significant deterioration of air quality. 52.2131 Section 52.2131 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a)-(b) (c) All applications and other information required...

  14. 40 CFR 52.1280 - Significant deterioration of air quality.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Significant deterioration of air quality. 52.1280 Section 52.1280 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) All applications and other information required pursuant to §...

  15. 40 CFR 52.581 - Significant deterioration of air quality.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Significant deterioration of air quality. 52.581 Section 52.581 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... deterioration of air quality. (a) All applications and other information required pursuant to § 52.21 of...

  16. 76 FR 57979 - Air University Board of Visitors Meeting

    Science.gov (United States)

    2011-09-19

    ... Department of the Air Force Air University Board of Visitors Meeting ACTION: Notice of Meeting of the Air... Officer at the address listed below at least five calendar days prior to the meeting which is the subject... at least five calendar days prior to the meeting for information on base entry passes. FOR...

  17. 49 CFR 1544.303 - Bomb or air piracy threats.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Bomb or air piracy threats. 1544.303 Section 1544... AND COMMERCIAL OPERATORS Threat and Threat Response § 1544.303 Bomb or air piracy threats. (a) Flight... upon receiving information that an act or suspected act of air piracy has been committed, the...

  18. Gulf of Mexico mud toxicity limitations

    Energy Technology Data Exchange (ETDEWEB)

    Dunn, H.E.; Beardmore, D.H. (Phillips Petroleum Co., Bartlesville, OK (USA)); Stewart, W.S. (Drilling Specialties Co. (US))

    1989-10-01

    Because of the Environmental Protection Agency's recent toxicity limits on drilling mud discharges for offshore Gulf of Mexico, Phillips Petroleum conducted a mud toxicity study based on both field and lab tests. The study, discussed in this article, found the polyanionic cellulose-sulfomethylated quebracho-chrome lignosulfonate mud Phillips had been using would comfortably pass the toxicity limitations. The study also found barite and thinners were of low toxicity, and hydrocarbons and surfactants were highly toxic.

  19. Ethnobotanical survey of toxic plants and plant parts in Ogun State, Nigeria

    Directory of Open Access Journals (Sweden)

    Adediwura A Fred-Jaiyesimi

    2012-01-01

    Full Text Available Background: Several plants considered toxic are sometimes identified in traditional medicinal recipes. This study identified and inventoried the plants and plant parts identified as toxic in targeted local government areas of Ogun State, Nigeria. Materials and Methods: By administering tested questionnaires, information on the poisonous or toxic plants, poisonous parts, poisonous effects, modes of poisoning, and antidotes was obtained. Results and Conclusion: Ninety-two species belonging to 43 families were identified as toxic plants and these were mainly members of the Euphorbiaceae and Fabaceae families. The botanical names, poisonous parts, common names, vernacular names, modes of poisoning, antidotes, and poisonous effects are presented in a table.

  20. Respiratory effects of air pollution on children.

    Science.gov (United States)

    Goldizen, Fiona C; Sly, Peter D; Knibbs, Luke D

    2016-01-01

    A substantial proportion of the global burden of disease is directly or indirectly attributable to exposure to air pollution. Exposures occurring during the periods of organogenesis and rapid lung growth during fetal development and early post-natal life are especially damaging. In this State of the Art review, we discuss air toxicants impacting on children's respiratory health, routes of exposure with an emphasis on unique pathways relevant to young children, methods of exposure assessment and their limitations and the adverse health consequences of exposures. Finally, we point out gaps in knowledge and research needs in this area. A greater understanding of the adverse health consequences of exposure to air pollution in early life is required to encourage policy makers to reduce such exposures and improve human health.

  1. Molecular mechanisms of homocysteine toxicity.

    Science.gov (United States)

    Boldyrev, A A

    2009-06-01

    Hyperhomocysteinemia is a risk factor for a number of cardiovascular and neurodegenerative processes as well as a complicating factor in normal pregnancy. Toxic effects of homocysteine and the product of its spontaneous oxidation, homocysteic acid, are based on their ability to activate NMDA receptors, increasing intracellular levels of ionized calcium and reactive oxygen species. Even a short-term exposure of cells to homocysteic acid at concentrations characteristic of hyperhomocysteinemia induces their apoptotic transformation. The discovery of NMDA receptors both in neuronal tissue and in several other tissues and organs (including immunocompetent cells) makes them a target for toxic action of homocysteine. The neuropeptide carnosine was found to protect the organism from homocysteine toxicity. Treatment of pregnant rats with carnosine under conditions of alimentary hyperhomocysteinemia increases viability and functional activity of their progeny.

  2. REACH. Air Conditioning Units.

    Science.gov (United States)

    Garrison, Joe; And Others

    As a part of the REACH (Refrigeration, Electro-Mechanical, Air-Conditioning, Heating) electromechanical cluster, this student manual contains individualized instructional units in the area of air conditioning. The instructional units focus on air conditioning fundamentals, window air conditioning, system and installation, troubleshooting and…

  3. The use of IV lipid emulsion for lipophilic drug toxicities.

    Science.gov (United States)

    Kaplan, Amy; Whelan, Megan

    2012-01-01

    IV lipid emulsion (ILE) therapy is emerging as a potential antidote for lipophilic drug toxicities in both human and veterinary medicine. ILE has already gained acceptance in human medicine as a treatment of local anesthetic systemic toxicity, but its mechanism of action, safety margins, and standardized dosing information remains undetermined at this time. Experimental and anecdotal use of ILE in the human and veterinary literature, theorized mechanisms of action, current dosing recommendations, potential adverse effects, and indications for use in human and veterinary emergency medicine are reviewed herein.

  4. Automated information retrieval using CLIPS

    Science.gov (United States)

    Raines, Rodney Doyle, III; Beug, James Lewis

    1991-01-01

    Expert systems have considerable potential to assist computer users in managing the large volume of information available to them. One possible use of an expert system is to model the information retrieval interests of a human user and then make recommendations to the user as to articles of interest. At Cal Poly, a prototype expert system written in the C Language Integrated Production System (CLIPS) serves as an Automated Information Retrieval System (AIRS). AIRS monitors a user's reading preferences, develops a profile of the user, and then evaluates items returned from the information base. When prompted by the user, AIRS returns a list of items of interest to the user. In order to minimize the impact on system resources, AIRS is designed to run in the background during periods of light system use.

  5. Ceftriaxone-induced toxic hepatitis

    Institute of Scientific and Technical Information of China (English)

    Erdal Peker; Eren Cagan; Murat Dogan

    2009-01-01

    Toxic hepatitis or drug-induced liver injury encompasses a spectrum of clinical disease ranging from mild biochemical abnormalities to acute liver failure. The advantages of a long half-life, wide spectrum, high tissue penetration rate, and a good safety profile,make ceftriaxone, a third-generation cephalosporin,a frequent choice in the treatment of childhood infections. Previous studies have reported a few cases of high aspartate aminotransferase and alanine aminotransferase levels, along with three cases ofhepatitis caused by ceftriaxone. Here, we report a case of drug-induced toxic hepatitis in a patient who was treated with ceftriaxone for acute tonsillitis.

  6. Lung toxicity of biodegradable nanoparticles.

    Science.gov (United States)

    Fattal, Elias; Grabowski, Nadége; Mura, Simona; Vergnaud, Juliette; Tsapis, Nicolas; Hillaireau, Hervé

    2014-10-01

    Biodegradable nanoparticles exhibit high potentialities for local or systemic drug delivery through lung administration making them attractive as nanomedicine carriers. However, since particulate matter or some inorganic manufactured nanoparticles exposed to lung cells have provoked cytotoxic effects, inflammatory and oxidative stress responses, it becomes important to investigate nanomedicine toxicity towards the lungs. This is the reason why, in the present review, the behavior of biodegradable nanoparticles towards the different parts of the respiratory tract as well as the toxicological consequences, measured on several models in vitro, ex vivo or in vivo, are described. Taken all together, the different studies carried out so far conclude on no or slight toxicity of biodegradable nanoparticles.

  7. Reactor modeling in heterogeneous photocatalysis: toxicity and biodegradability assessment.

    Science.gov (United States)

    Satuf, M L; José, S; Paggi, J C; Brandi, R J; Cassano, A E; Alfano, O M

    2010-01-01

    Photocatalysis employing titanium dioxide is a useful method to degrade a wide variety of organic and inorganic pollutants from water and air. However, the application of this advanced oxidation process at industrial scale requires the development of mathematical models to design and scale-up photocatalytic reactors. In the present work, intrinsic kinetic expressions previously obtained in a laboratory reactor are employed to predict the performance of a bench scale reactor of different configuration and operating conditions. 4-Chlorophenol was chosen as the model pollutant. The toxicity and biodegradability of the irradiated mixture in the bench photoreactor was also assessed. Good agreement was found between simulation and experimental data. The root mean square error of the estimations was 9.9%. The photocatalytic process clearly enhances the biodegradability of the reacting mixture, and the initial toxicity of the pollutant was significantly reduced by the treatment.

  8. Concentration-time data in toxicity tests and resulting relationships

    Science.gov (United States)

    Hilado, C. J.; Brauer, D. P.

    1979-01-01

    Periodic analyses for carbon monoxide and methane in the animal exposure chamber during pyrolysis of polyethylene at 800 C without forced air flow showed that the concentrations of these compounds increased with exposure time. These observations, and similar observations for polyurethane flexible foam, permitted the calculation of carbon monoxide toxicity in terms of a DP (Death Product Concentration) value, in addition to flammability in terms of HC (Hydro Carbon) value. Observed DP values exceeding the critical DP(CO) value of 47,200 ppm-min for carbon monoxide may indicate that lethal exposures were reached earlier but not immediately manifested because of the time delay involved in physiological processes. On the basis of this DP(CO) value, carbon monoxide could have been the sole toxicant in the case of polyethylene, polypropylene, polyoxymethylene, polystyrene, polycarbonate, ethylene propylene diene rubber, and wood.

  9. Theorizing Information for Information Science.

    Science.gov (United States)

    Cornelius, Ian

    2002-01-01

    Considers whether information science has a theory of information. Highlights include guides to information and its theory; constructivism; information outside information science; process theories; cognitive views of information; measuring information; meaning; and misinformation. (Contains 89 references.) (LRW)

  10. The air pollution index system in Hong Kong

    Energy Technology Data Exchange (ETDEWEB)

    Lee, F.Y.P.; Gervat, G.P. [Hong Kong Government, Wanchai (Hong Kong). Environmental Protection Dept.

    1995-12-31

    The Hong Kong Environmental Protection Department (EPD) is currently operating an air quality monitoring network in the territory. There are nine monitoring stations, each with air quality monitoring equipment, meteorological instruments and a data logger. Five minute averaged data are transmitted through telephone lines to the central computer at the EPD Air Laboratory and are also stored in the data logger on site, as backup. At present, the EPD releases its air quality measurements to the public via monthly and special press releases, and annual reports. However, as public awareness of air pollution problems has increased, there has been an urgent need for timely and simpler information about air pollution levels. The development and operation of an Air Pollution Index (API) system has addressed that need. This presentation discusses the API computation, the information and advice released to the general public and how they can access the API information. Some API results are also presented. (author)

  11. Tadpole toxicity prediction using chromatographic systems.

    Science.gov (United States)

    Fernández-Pumarega, Alejandro; Amézqueta, Susana; Fuguet, Elisabet; Rosés, Martí

    2015-10-30

    Toxicity has been emulated in tadpole species through chromatographic systems. The parameter studied to evaluate the non-specific toxicity of a compound is the narcosis concentration (Cnar), which is defined as the concentration needed for the immobilization of the organism. Because experimental investigation with animals is lengthy, costly, technically difficult, and ethically questionable, there is a great interest in developing surrogate physicochemical systems able to emulate biological systems to obtain the same information in a faster, more economic, and easier manner. In order to see which chromatographic systems would be able to emulate tadpole narcosis, both, tadpole narcosis data and data in several chromatographic and electrophoretic systems, were fitted to a linear solvation energy relationship (LSER) model. Thus, by comparison of the models it was possible to see which of the chromatographic systems were more similar to the biological one. The physicochemical systems that best emulate tadpole narcosis were an HPLC system based on an immobilized artificial membrane (IAM) column, and two micellar electrokinetic chromatography (MEKC) systems based on sodium taurocholate (STC) and a mixture of sodium dodecylsulphate (SDS) and Brij 35 as surfactants. A system based on a RP18 HPLC column also was selected for comparison because it is a common column in most analytical laboratories. To establish the models, a set of compounds with known Cnar values were analyzed in the chromatographic, and electrophoretic selected systems and, then, the retention factor (k) was correlated to the concentration of narcosis. Statistics showed that the system based on STC micelles was the best to emulate toxicity in tadpoles. The robustness and predictive ability of the developed models were validated.

  12. CHEMICAL STRUCTURE INDEXING OF TOXICITY DATA ON THE INTERNET: MOVING TOWARDS A FLAT WORLD

    Science.gov (United States)

    Standardized chemical structure annotation of public toxicity databases and information resources is playing an increasingly important role in the 'flattening' and integration of diverse sets of biological activity data on the Internet. This review discusses public initiatives th...

  13. 40 CFR 79.62 - Subchronic toxicity study with specific health effect assessments.

    Science.gov (United States)

    2010-07-01

    ... will provide screening information on target organ toxicities and on concentration levels useful for... through concentration range-finding trials prior to starting this study. This health effects screening... (if present); esophagus; stomach; duodenum; jejunum; ileum; cecum; colon; rectum; urinary...

  14. Fluoropyrimidine and platinum toxicity pharmacogenetics: an umbrella review of systematic reviews and meta-analyses.

    Science.gov (United States)

    Campbell, Jared M; Bateman, Emma; Peters, Micah Dj; Bowen, Joanne M; Keefe, Dorothy M; Stephenson, Matthew D

    2016-03-01

    Fluoropyrimidine (FU) and platinum-based chemotherapies are greatly complicated by their associated toxicities. This umbrella systematic review synthesized all systematic reviews that investigated associations between germline variations and toxicity, with the aim of informing personalized medicine. Systematic reviews are important in pharmacogenetics where false positives are common. Four systematic reviews were identified for FU-induced toxicity and three for platinum. Polymorphisms of DPYD and TYMS, but not MTHFR, were statistically significantly associated with FU-induced toxicity (although only DPYD had clinical significance). For platinum, GSTP1 was found to not be associated with toxicity. This umbrella systematic review has synthesized the best available evidence on the pharmacogenetics of FU and platinum toxicity. It provides a useful reference for clinicians and identifies important research gaps.

  15. Evaluate the potential environmental toxicity of quantum dots on ciliated protozoa by microcalorimetry

    Energy Technology Data Exchange (ETDEWEB)

    Xiao, Qi [College of Chemistry and Life Science, Guangxi Teachers Education University, Nanning 530001 (China); State Key Laboratory of Virology, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072 (China); Huang, Shan, E-mail: huangs@whu.edu.cn [College of Chemistry and Life Science, Guangxi Teachers Education University, Nanning 530001 (China); State Key Laboratory of Virology, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072 (China); Su, Wei [College of Chemistry and Life Science, Guangxi Teachers Education University, Nanning 530001 (China); Li, Peiyuan [College of Pharmacy, Guangxi Traditional Chinese Medical University, Nanning 530001 (China); Liang, Zuocui; Ou, Jianzhen; Ma, Jianqiang [College of Chemistry and Life Science, Guangxi Teachers Education University, Nanning 530001 (China); Liu, Yi, E-mail: prof.liuyi@263.net [State Key Laboratory of Virology, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072 (China)

    2012-11-10

    Highlights: Black-Right-Pointing-Pointer The toxic effects of QDs to T. thermophila BF{sub 5} using a TAM air microcalorimeter. Black-Right-Pointing-Pointer QDs were acutely toxic for T. thermophila BF{sub 5} growth in a dose-dependent manner. Black-Right-Pointing-Pointer The toxicity of different ligands-capped QDs on T. thermophila BF{sub 5} was investigated. Black-Right-Pointing-Pointer QDs could be ingested by cells and affect the morphology of T. thermophila BF{sub 5}. - Abstract: In the present study, we evaluated the toxic effects of mercaptoacetic acid (MAA)-capped CdSe QDs and CdSe/ZnS QDs to particle-ingesting model ciliated protozoa Tetrahymena thermophila BF{sub 5} (T. thermophila BF{sub 5}) by using a TAM air isothermal microcalorimeter. These results suggested that both MAA-CdSe QDs and MAA-CdSe/ZnS QDs were indeed acutely toxic for T. thermophila BF{sub 5} growth in a dose-dependent manner, and the toxicities of both MAA-CdSe QDs and MAA-CdSe/ZnS QDs increased dramatically after UV irradiation due to the liberation of more toxic Cd{sup 2+}, which indicated that the toxicity of MAA-CdSe/ZnS QDs was less than that of MAA-CdSe QDs. Furthermore, the toxicity of different ligands-capped CdSe/ZnS QDs on T. thermophila BF{sub 5} was also investigated. The uptake of MAA-CdSe/ZnS QDs and adenosine 5 Prime -monophosphate (AMP)-CdSe/ZnS QDs by cells and the morphological change during the process of T. thermophila BF{sub 5} growth incubated with these QDs were further studied by fluorescence inverted microscopy.

  16. Equipment for Measuring Air Flow, Air Temperature, Relative Humidity, and Carbon Dioxide in Schools. Technical Bulletin.

    Science.gov (United States)

    Jacobs, Bruce W.

    Information on equipment and techniques that school facility personnel may use to evaluate IAQ conditions are discussed. Focus is placed on the IAQ parameters of air flow, air temperature, relative humidity, as well as carbon dioxide and the equipment used to measure these factors. Reasons for measurement and for when the measurement of these…

  17. Air Quality and Air Pollution Management in Urban Areas in Less Developed Countries

    DEFF Research Database (Denmark)

    Madsen, P. V.

    2007-01-01

    The working group will address the complexity of air pollution management in the growing urban sphere in the less developed countries, and will discus and evaluate how Danish and Scandinavian research institutions, universities and private companies can initiate a more progressive role...... in development aid and capacity development in relation to air pollution. For further information on the actions objective, activities and dissemination plan...

  18. [Molybdenum as an air pollutant].

    Science.gov (United States)

    Lindner, R; Junker, E; Hoheiser, H

    1990-07-01

    Investigations into the reasons for the retarded growth and discolouration of a small area of a field of rape situated on the outskirts of Vienna revealed higher than normal levels of molybdenum in the soil (up to 430 micrograms/l) and in the water (up to 9.7 mg/l). The source of the pollution was traced to a neighbouring industrial plant that was emitting the metal via the chimney stack. A review of the literature on the toxic effects of molybdenum in general and as an air pollutant in particular is provided. This shows that, in contrast to animals, this effect is relatively small in humans and plants. Nevertheless, the occupation-related inhalation of the metal has been shown to be associated with pneumoconiosis and gout-like symptoms.

  19. Fumigation Toxicity of Essential Oil Monoterpenes to Callosobruchus maculatus (Coleoptera: Chrysomelidae: Bruchinae

    Directory of Open Access Journals (Sweden)

    Olufunmilayo E. Ajayi

    2014-01-01

    Full Text Available The fumigant toxicity of eight essential oil components, 1-8-cineole, carvacrol, eugenol, (−-menthone, (−-linalool, S-(−-limonene, (−-β-pinene, and (+-α-pinene, was tested against the cowpea weevil, Callosobruchus maculatus (Fabricius (Coleoptera: Chrysomelidae, at 0.25–60 µL/L air doses. 1-8-Cineole, carvacrol, and eugenol caused complete adult mortality at 10 µL/L air 24 h after treatment. 1-8-Cineole and carvacrol were the most toxic with LD50 values of 0.24 and 0.6 µL/L air at 24 h, respectively. (−-β-Pinene and (+-α-pinene were the least toxic with LD50 values of 31 and 31.4 µL/L air at 24 h, respectively. Toxicity was negatively correlated with vapor pressure. 1-8-Cineole and carvacrol caused 100% oviposition deterrence at all doses tested. Eugenol and (−-menthone completely inhibited adult emergence. S-(−-Limonene, (−-β-pinene, and (+-α-pinene were not effective at preventing oviposition or adult emergence, suggesting that a lethal dose of the three oil components would be necessary to control C. maculatus infestations.

  20. Speciation Profiles and Toxic Emission Factors for Nonroad Engines: DRAFT REPORT

    Science.gov (United States)

    This document details the research and development behind how MOVES2014a estimates air toxic emissions for nonroad engines and equipment run on conventional gasoline without ethanol (E0) and gasoline blended with 10% ethanol (E10) as well as diesel fuel, compressed natural gas (C...

  1. EMISSION FACTORS FOR IRON AND STEEL SOURCES: CRITERIA AND TOXIC POLLUTANTS

    Science.gov (United States)

    The report provides a comprehensive set of emission factors for sources of both criteria and toxic air pollutants in integrated iron and steel plants and specialty electric arc shops (minimills). Emission factors are identified for process sources, and process and open source fug...

  2. Air movement and perceived air quality

    DEFF Research Database (Denmark)

    Melikov, Arsen Krikor; Kaczmarczyk, J.

    2012-01-01

    The impact of air movement on perceived air quality (PAQ) and sick building syndrome (SBS) symptoms was studied. In total, 124 human subjects participated in four series of experiments performed in climate chambers at different combinations of room air temperature (20, 23, 26 and 28 °C), relative...... and the humidity of the room air. At a low humidity level of 30% an increased velocity could compensate for the decrease in perceived air quality due to an elevated temperature ranging from 20 °C to 26 °C. In a room with 26 °C, increased air movement was also able to compensate for an increase in humidity from 30...

  3. Comparative gene expression in toxic versus non-toxic strains of the marine dinoflagellate Alexandrium minutum

    Directory of Open Access Journals (Sweden)

    Glöckner Gernot

    2010-04-01

    Full Text Available Abstract Background The dinoflagellate Alexandrium minutum typically produces paralytic shellfish poisoning (PSP toxins, which are known only from cyanobacteria and dinoflagellates. While a PSP toxin gene cluster has recently been characterized in cyanobacteria, the genetic background of PSP toxin production in dinoflagellates remains elusive. Results We constructed and analysed an expressed sequence tag (EST library of A. minutum, which contained 15,703 read sequences yielding a total of 4,320 unique expressed clusters. Of these clusters, 72% combined the forward-and reverse reads of at least one bacterial clone. This sequence resource was then used to construct an oligonucleotide microarray. We analysed the expression of all clusters in three different strains. While the cyanobacterial PSP toxin genes were not found among the A. minutum sequences, 192 genes were differentially expressed between toxic and non-toxic strains. Conclusions Based on this study and on the lack of identified PSP synthesis genes in the two existent Alexandrium tamarense EST libraries, we propose that the PSP toxin genes in dinoflagellates might be more different from their cyanobacterial counterparts than would be expected in the case of a recent gene transfer. As a starting point to identify possible PSP toxin-associated genes in dinoflagellates without relying on a priori sequence information, the sequences only present in mRNA pools of the toxic strain can be seen as putative candidates involved in toxin synthesis and regulation, or acclimation to intracellular PSP toxins.

  4. AIRPLANE INFORMATION

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Air France Over the past few years. Air France has been committed to bringing its brand image up-to-date. Today, Air France unveils an important new stage, its revamped logo. To avoid additional costs, the change will be made gradually. Aircraft will be painted with the new

  5. Indoor air quality and health

    Science.gov (United States)

    Jones, A. P.

    During the last two decades there has been increasing concern within the scientific community over the effects of indoor air quality on health. Changes in building design devised to improve energy efficiency have meant that modern homes and offices are frequently more airtight than older structures. Furthermore, advances in construction technology have caused a much greater use of synthetic building materials. Whilst these improvements have led to more comfortable buildings with lower running costs, they also provide indoor environments in which contaminants are readily produced and may build up to much higher concentrations than are found outside. This article reviews our current understanding of the relationship between indoor air pollution and health. Indoor pollutants can emanate from a range of sources. The health impacts from indoor exposure to combustion products from heating, cooking, and the smoking of tobacco are examined. Also discussed are the symptoms associated with pollutants emitted from building materials. Of particular importance might be substances known as volatile organic compounds (VOCs), which arise from sources including paints, varnishes, solvents, and preservatives. Furthermore, if the structure of a building begins to deteriorate, exposure to asbestos may be an important risk factor for the chronic respiratory disease mesothelioma. The health effects of inhaled biological particles can be significant, as a large variety of biological materials are present in indoor environments. Their role in inducing illness through immune mechanisms, infectious processes, and direct toxicity is considered. Outdoor sources can be the main contributors to indoor concentrations of some contaminants. Of particular significance is Radon, the radioactive gas that arises from outside, yet only presents a serious health risk when found inside buildings. Radon and its decay products are now recognised as important indoor pollutants, and their effects are

  6. Understanding how data triangulation identifies acute toxicity of novel psychoactive drugs.

    Science.gov (United States)

    Wood, D M; Dargan, P I

    2012-09-01

    Over the last decade, there has been an increase in the availability and use of novel psychoactive substances (also known as "legal highs"). There is limited information available on the potential acute toxicity (harms) associated with the use of these novel psychoactive substances. Gold standard evidence, such as animal studies or human clinical trials, is rarely available to users or healthcare professionals. However, it is possible to use triangulation of data on the acute toxicity from multiple sources to describe the overall pattern of toxicity associated with a novel psychoactive substance. In this review, we will describe these potential data sources, which include self-reported toxicity on internet discussion fora, data from sub-population user surveys, data from regional and national poisons information services and published case reports and case series. We will then describe how pattern of acute toxicity associated with the use of the cathinone mephedrone (4-methylmethcathinone) was established using triangulation of these different data sources.

  7. DOE contractor's meeting on chemical toxicity

    Energy Technology Data Exchange (ETDEWEB)

    1987-01-01

    The Office of Health and Environmental Research (OHER) is required to determine the potential health and environmental effects associated with energy production and use. To ensure appropriate communication among investigators and scientific disciplines that these research studies represent, OHER has sponsored workshops. This document provides a compilation of activities at the Third Annual DOE/OHER Workshop. This year's workshop was broadened to include all OHER activities identified as within the chemical effects area. The workshop consisted of eight sessions entitled Isolation and Detection of Toxic chemicals; Adduct Formation and Repair; Chemical Toxicity (Posters); Metabolism and Genotoxicity; Inhalation Toxicology; Gene Regulation; Metals Toxicity; and Biological Mechanisms. This document contains abstracts of the information presented by session.

  8. Effects of Heavy Metal Toxicity on Human Health

    Directory of Open Access Journals (Sweden)

    Guluzar Ozbolat

    2016-12-01

    Full Text Available Heavy metals are the elements that can be toxic even at low concentrations. It is often used as a group name for metals and semimetals (metalloids that have been associated with contamination and potential toxicity or ecotoxicity. Heavy metals are toxic to human health. Because it cannot be discarded with (kidney, liver intestine, skin, lung without special support from most of the body's normal excretion routes Therefore, a large part of the heavy metals accumulate in biological organisms. As a result of the accumulation of these metals that are focused within living things, when they have reached the effective dose severe diseases (such as autism neurological, thyroid and infertility even can cause death. In this review information about the properties and effects of some heavy metals that affects human health have been provided.. [Archives Medical Review Journal 2016; 25(4.000: 502-521

  9. [Research on advance of health effects of nanoparticles on air pollution in China].

    Science.gov (United States)

    Xiong, Lilin; Wu, Tianshu; Tang, Meng

    2015-09-01

    The adverse health effects of fine particles in the air pollution has been confirmed, and health consequences induced by ultrafine particles (mass media aerodynamic diameter biological effects and potential toxicity mechanisms of some common nanoparticles in the atmosphere on the major tissues and organs. Finally, the research focus of the nano particles in air pollutants was also presented.

  10. Borocaptate sodium (BSH) toxicity issues

    Energy Technology Data Exchange (ETDEWEB)

    LaHann, T.

    1995-11-01

    ISU`s Center for Toxicology Research has been conducting toxicity testing of borocaptate sodium (BSH) to aid in assessing if proposed human studies of BSH are likely to be acceptably safe. This report describes BSH interactions with other biological agents.

  11. Gossypol Toxicity from Cottonseed Products

    Directory of Open Access Journals (Sweden)

    Ivana Cristina N. Gadelha

    2014-01-01

    Full Text Available Gossypol is a phenolic compound produced by pigment glands in cotton stems, leaves, seeds, and flower buds (Gossypium spp.. Cottonseed meal is a by-product of cotton that is used for animal feeding because it is rich in oil and proteins. However, gossypol toxicity limits cottonseed use in animal feed. High concentrations of free gossypol may be responsible for acute clinical signs of gossypol poisoning which include respiratory distress, impaired body weight gain, anorexia, weakness, apathy, and death after several days. However, the most common toxic effects is the impairment of male and female reproduction. Another important toxic effect of gossypol is its interference with immune function, reducing an animal’s resistance to infections and impairing the efficiency of vaccines. Preventive procedures to limit gossypol toxicity involve treatment of the cottonseed product to reduce the concentration of free gossypol with the most common treatment being exposure to heat. However, free gossypol can be released from the bound form during digestion. Agronomic selection has produced cotton varieties devoid of glands producing gossypol, but these varieties are not normally grown because they are less productive and are more vulnerable to attacks by insects.

  12. The Effect of Toxic Leadership

    Science.gov (United States)

    2012-03-15

    for everything their organizations do or fail to do. However, does centralizing power in this manner lead to abuses and toxicity? According to Edmund ... Burke , ―Power, in whatever hands, is rarely guilty of too strict limitations on itself.‖115 The U.S. Government is strengthened by a system of

  13. Sparfloxacin induced toxic epidermal necrolysis

    Directory of Open Access Journals (Sweden)

    Ramesh M

    2003-05-01

    Full Text Available Toxic epidermal necrolysis (TEN is a life-threatening cutaneous adverse drug reaction. TEN is known to occur with the fluoroquinolone class of antibiotics, but only four cases of sparfloxacin induced TEN have been reported to the WHO database. This is another case report of sparfloxacin induced TEN.

  14. Iodine toxicity and its amelioration.

    Science.gov (United States)

    Baker, David H

    2004-06-01

    Iodine (I) toxicity is rare in animals and humans, but nuclear explosions that give off radioactive I and excessive stable I ingestion in parts of the world where seaweed is consumed represent specialized I toxicity concerns. Chronic overconsumption of I reduces organic binding of I by the thyroid gland, which results in hypothyroidism and goiter. Bromine can replace I on position 5 of both T(3) and T(4) with no loss of thyroid hormone activity. Avian work has also demonstrated that oral bromide salts can reverse the malaise and growth depressions caused by high doses of I (as KI) added as supplements to the diet. Newborn infants by virtue of having immature thyroid glands are most susceptible to I toxicity, whether of stable or radioactive origin. For the latter, the 1986 Chernobyl nuclear accident in Belarus has provided evidence that KI blockage therapy for exposed individuals 18 years of age and younger is effective in minimizing the development of thyroid cancer. Whether bromide therapy has a place in I toxicity situations remains to be determined.

  15. Technological, economic, and political feasibility in OSHA's Air Contaminants Standard

    Energy Technology Data Exchange (ETDEWEB)

    Robinson, J.C.; Paxman, D.G. (Univ. of California, Berkeley (USA))

    In 1989, after almost two decades of substance-by-substance standard setting, the Occupational Safety and Health Administration (OSHA) promulgated its Air Contaminants Standard, imposing new exposure limits for 376 toxic substances encountered in U.S. industry. In marked contrast to earlier regulations, the Air Contaminants Standard has generated relatively little industry opposition. This paper analyzes the standard in the context of the twenty-year debate over the appropriate role for technological feasibility and economic compliance costs in occupational health policy. The political feasibility of the new standard is traced to OSHA's abandonment of technology forcing in favor of reliance on off-the-shelf technologies already in use in major firms. While important as an embodiment of OSHA's new generic approach to regulation, the Air Contaminants Standard cannot serve as a model for future occupational health policy, due to its reliance on informal, closed-door mechanisms for establishing regulatory priorities and permissible exposure limits. 20 refs.

  16. Information technology equipment cooling system

    Science.gov (United States)

    Schultz, Mark D.

    2014-06-10

    According to one embodiment, a system for removing heat from a rack of information technology equipment may include a sidecar indoor air to liquid heat exchanger that cools warm air generated by the rack of information technology equipment. The system may also include a liquid to liquid heat exchanger and an outdoor heat exchanger. The system may further include configurable pathways to connect and control fluid flow through the sidecar heat exchanger, the liquid to liquid heat exchanger, the rack of information technology equipment, and the outdoor heat exchanger based upon ambient temperature and/or ambient humidity to remove heat from the rack of information technology equipment.

  17. Progress in Assessing Air Pollutant Risks from In Vitro Exposures: Matching Ozone Dose and Effect in Human Air Way Cells

    Science.gov (United States)

    In vitro exposures to air pollutants could, in theory, facilitate a rapid and detailed assessment of molecular mechanisms of toxicity. However, it is difficult to ensure that the dose of a gaseous pollutant to cells in tissue culture is similar to that of the same cells during in...

  18. Predictive dosimetric parameters for gastrointestinal toxicity with hypofractioned radiotherapy in pancreatic adenocarcinoma

    Directory of Open Access Journals (Sweden)

    Liu X

    2016-04-01

    Full Text Available Xian Liu,* Gang Ren,* Liqin Li, Tingyi Xia Department of Radiation Oncology, Air Force General Hospital, Beijing, People’s Republic of China *These authors contributed equally to this work Abstract: To better guide the development and optimization of radiotherapy planning, to reduce the incidence of radiation reactions, and to improve the quality of life of the patients with pancreatic cancer using radiotherapy, we conducted this study to explore the dosimetric parameters that predict the risk of gastrointestinal (GI toxicity with hypofractioned radiotherapy for pancreatic cancer. Between January 2014 and January 2015, the medical records of 68 patients with pancreatic cancer who underwent helical tomotherapy at the Air Force General Hospital were analyzed. The doses delivered to the planning target volume, clinical target volume, and gross tumor volume–internal gross tumor volume of the primary pancreatic lesions were 50, 60, and 70–80 Gy in 15–20 fractions, respectively. GI toxicity was scored according to version 4.0 of the National Cancer Institute Common Terminology Criteria for Adverse Events. The stomach and duodenum were contoured separately to determine the dose–volume histogram parameters. Univariate and multivariate analyses were adopted to identify clinical and physical risk factors associated with GI toxicity. The median follow-up was 9 months (range: 4–16 months. Eighteen patients had grade II acute GI toxicity, one patient had grade III acute GI toxicity, 17 patients had grade II late GI toxicity, and one patient had grade III late GI toxicity. On univariate analysis, the volume, the average dose Dmean, the maximum dose to 1, 3, 5, and 10 cm3 of the stomach and duodenum (D1, D3, D5, and D10, and the relative volumes receiving 5–40 Gy (V5–V40, and the absolute volumes receiving 5–45 Gy (aV5–aV45 of the duodenum were significantly associated with grade II or higher GI toxicity (P<0.05. On multivariate

  19. Clean Air Act. Revision 5

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-15

    This Reference Book contains a current copy of the Clean Air Act, as amended, and those regulations that implement the statute and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. This Reference Book has been completely revised and is current through February 15, 1994.

  20. Environmental Assessment for the Construction and Operation of a Battalion Headquarters for the U.S. Army Priority Air Transport at Joint Base Andrews-Naval Air Facility Washington, Prince George’s County, Maryland

    Science.gov (United States)

    2012-12-01

    Wastewater Program, and Toxics/Asbestos Program. To learn more about each program click here. Polution Prevention Pollution Prevention The Air Force...PRIORITY AIR TRANSPORT AT JOINT BASE ANDREWS-NAVAL AIR FACILITY W ASillNGTON, MARYLAND INTRODUCTION The attached environmental assessment (EA) examines...the potential impacts on the environment from the Proposed Action to construct and operate a battalion headquarters for the U.S. Army Priority Air

  1. Developing a fuzzy model for Tehran's air quality

    Directory of Open Access Journals (Sweden)

    Nafiseh Tokhmehchi

    2015-01-01

    Full Text Available This research aims to offer a fuzzy approach for calculating Tehran's air pollution index. The method is based on fuzzy analysis model, and uses the information about air quality index (AQI, included on the website of Tehran’s Air Quality Monitoring And Supervision Bureau. The contrived fuzzy logic is considered a powerful tool for demonstrating the information associated with uncertainty. In the end, several graphs visualize this inferential system in various levels of pollution.

  2. Moderate increase of radioactivity in air, attributable of beta emitter radionuclides, in France at the end of September 2011; Elevation moderee de la radioactivite dans l'air, imputable aux radionucleides emetteurs beta, en France fin septembre 2011. Note d'information

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    Within the frame of the regular monitoring of radioactivity in the environment about its nuclear sites, EDF has noticed a moderate but unusual increase of radioactivity in the air. This radioactivity is attributed to beta emitter radionuclides. This document reports and comments measurements performed by EDF and the IRSN (the French Institute for radiation protection and nuclear safety), and additional investigations performed by the IRSN. The possible origin of the radioactivity increase is discussed in terms of meteorological conditions and dust accumulation levels, and of their incidence of activity levels in the air

  3. Toxic Volatile Organic Compounds (VOCs in the Atmospheric Environment: Regulatory Aspects and Monitoring in Japan and Korea

    Directory of Open Access Journals (Sweden)

    Wen-Tien Tsai

    2016-09-01

    Full Text Available In the past decades, hazardous air pollutants (HAPs, so-called air toxics or toxic air pollutants, have been detected in the atmospheric air at low concentration levels, causing public concern about the adverse effect of long-term exposure to HAPs on human health. Most HAPs belong to volatile organic compounds (VOCs. More seriously, most of them are known carcinogens or probably carcinogenic to humans. The objectives of this paper were to report the regulatory aspects and environmental monitoring management of toxic VOCs designated by Japan and Korea under the Air Pollution Control Act, and the Clean Air Conservation Act, respectively. It can be found that the environmental quality standards and environmental monitoring of priority VOCs (i.e., benzene, trichloroethylene, tetrachloroethylene, and dichloromethane have been set and taken by the state and local governments of Japan since the early 2000, but not completely established in Korea. On the other hand, the significant progress in reducing the emissions of some toxic VOCs, including acrylonitrile, benzene, 1,3-butadiene, 1,2-dichloroethane, dichloromethane, chloroform, tetrachloroethylene, and trichloroethylene in Japan was also described as a case study in the brief report paper.

  4. Your Right to Clean Air, A Manual for Citizen Action.

    Science.gov (United States)

    1970

    This manual provides the citizen with basic information for taking action against air pollution. A summary of the effects of various concentrations of sulfur oxides, particulate matter, carbon monoxide, photochemical smog, and hydrocarbons is presented. Suggestions are made for obtaining information about community air pollution problems, and how…

  5. Evaluation of AirGIS: a GIS-based air pollution and human exposure modelling system

    DEFF Research Database (Denmark)

    Ketzel, Matthias; Berkowicz, Ruwim; Hvidberg, Martin

    2011-01-01

    This study describes in brief the latest extensions of the Danish Geographic Information System (GIS)-based air pollution and human exposure modelling system (AirGIS), which has been developed in Denmark since 2001 and gives results of an evaluation with measured air pollution data. The system...... shows, in general, a good performance for both long-term averages (annual and monthly averages), short-term averages (hourly and daily) as well as when reproducing spatial variation in air pollution concentrations. Some shortcomings and future perspectives of the system are discussed too....

  6. Hanford Site radionuclide national emission standards for hazardous air pollutants registered stack source assessment

    Energy Technology Data Exchange (ETDEWEB)

    Davis, W.E.; Barnett, J.M.

    1994-07-01

    On February 3, 1993, the US Department of Energy, Richland Operations Office received a Compliance Order and Information Request from the Director of the Air and Toxics Division of the US Environmental Protection Agency,, Region 10. The Compliance Order requires the Richland Operations Office to evaluate all radionuclide emission points at the Hanford Site . The evaluation also determined if the effective dose equivalent from any of these stack emissions exceeded 0.1 mrem/yr, which will require the stack to have continuous monitoring. The result of this assessment identified a total of 16 stacks as having potential emissions that,would cause an effective dose equivalent greater than 0.1 mrem/yr.

  7. Chitin Adsorbents for Toxic Metals: A Review

    Directory of Open Access Journals (Sweden)

    Ioannis Anastopoulos

    2017-01-01

    Full Text Available Wastewater treatment is still a critical issue all over the world. Among examined methods for the decontamination of wastewaters, adsorption is a promising, cheap, environmentally friendly and efficient procedure. There are various types of adsorbents that have been used to remove different pollutants such as agricultural waste, compost, nanomaterials, algae, etc., Chitin (poly-β-(1,4-N-acetyl-d-glucosamine is the second most abundant natural biopolymer and it has attracted scientific attention as an inexpensive adsorbent for toxic metals. This review article provides information about the use of chitin as an adsorbent. A list of chitin adsorbents with maximum adsorption capacity and the best isotherm and kinetic fitting models are provided. Moreover, thermodynamic studies, regeneration studies, the mechanism of adsorption and the experimental conditions are also discussed in depth.

  8. Tetrodotoxin: Chemistry, Toxicity, Source, Distribution and Detection

    Directory of Open Access Journals (Sweden)

    Vaishali Bane

    2014-02-01

    Full Text Available Tetrodotoxin (TTX is a naturally occurring toxin that has been responsible for human intoxications and fatalities. Its usual route of toxicity is via the ingestion of contaminated puffer fish which are a culinary delicacy, especially in Japan. TTX was believed to be confined to regions of South East Asia, but recent studies have demonstrated that the toxin has spread to regions in the Pacific and the Mediterranean. There is no known antidote to TTX which is a powerful sodium channel inhibitor. This review aims to collect pertinent information available to date on TTX and its analogues with a special emphasis on the structure, aetiology, distribution, effects and the analytical methods employed for its detection.

  9. Toxicity of nanomaterials; an undermined issue.

    Science.gov (United States)

    Mogharabi, Mehdi; Abdollahi, Mohammad; Faramarzi, Mohammad Ali

    2014-08-15

    Nanomaterials are employed in extensive variety of commercial products such as electronic components, cosmetics, food, sports equipment, biomedical applications, and medicine. With the increasing utilization of engineered nanomaterials, the potential exposure of human to nanoparticles is rapidly increasing. Nowadays when new nanomaterials with new applications are introduced, mostly good and positive effects are mentioned whereas possible hazards arising from nanosize of the compounds are undermined. Toxicology studies of nanomaterials demonstrate some adverse effects in some human organs such as central nerve system, immune system, and lung. There is lack of complete information about human toxicity and environmental waste of nanomaterials. We aimed to highlight current toxicological concerns of potentially useful nanomaterials which are now used in pharmaceutical and biomedical sciences.

  10. Toxicity of Nutmeg (Myristicin: A Review

    Directory of Open Access Journals (Sweden)

    Rahman N.A.A

    2015-01-01

    Full Text Available In this paper a detailed review of myristicin is reported. Numerous literatures report that myristicin is responsible for hallucinogenic effects, which induced by the consumption of nutmeg due to its metabolism structure of 3-methoxy-4,5-methylendioxyamphetamine (MMDA. Minimum dosage of nutmeg that can cause psychogenic effect is 5 g (ground nutmeg with 1 to 2 mg myristicin content and this dosage is considered as ‘toxic dose’. At higher dosage of myristicin death may occur. Additionally, Myristicin poisoning can lead to many health problems that related to brain problem. Those symptoms usually occur 3 to 6 hours after ingestion of myristicin or foodstuffs containing it, and effects may persist up to 72 hours. California Poison Control System (CPCS electronic database 72.3% exposures between 1997 and 2008 that were intentional for recreational purposes (between ages 13 and 20 years old. The remaining considered as unintentionally exposed. Between 1998 to 2008, Texas Poison Center Network (TPCN received seventeen nutmeg poisoning and 64.7% from that cases involved abuse, and the rest was unintentional exposure. Most of the nutmeg exposures were via the oral route and minor cases of nutmeg exposure occurred through insufflated nutmeg, unintentional dermal and ocular exposures. Nutmeg also has been misused by mixing it with other drugs in order to get “high”. For intoxication cases, treatments like decontamination (cathartic, charcoal, dilution, fresh air, IV fluids and supportive care (benzodiazepines will be provided to reduce the effects.

  11. Connectable solar air collectors

    Energy Technology Data Exchange (ETDEWEB)

    Oestergaard Jensen, S.; Bosanac, M.

    2002-02-01

    The project has proved that it is possible to manufacture solar air collector panels, which in an easy way can be connected into large collector arrays with integrated ducting without loss of efficiency. The developed connectable solar air collectors are based on the use of matrix absorbers in the form of perforated metal sheets. Three interconnected solar air collectors of the above type - each with an transparent area of approx. 3 m{sup 2} - was tested and compared with parallel tests on two single solar air collectors also with a transparent area of approx. 3 m{sup 2} One of the single solar air collectors has an identical absorber as the connectable solar air collectors while the absorber of the other single solar air collector was a fibre cloth. The efficiency of the three solar air collectors proved to be almost identical in the investigated range of mass flow rates and temperature differences. The solar air collectors further proved to be very efficient - as efficient as the second most efficient solar air collectors tested in the IEA task 19 project Solar Air Systems. Some problems remain although to be solved: the pressure drop across especially the connectable solar air collectors is too high - mainly across the inlets of the solar air collectors. It should, however, be possible to considerably reduce the pressure losses with a more aerodynamic design of the inlet and outlet of the solar air collectors; The connectable solar air collectors are easy connectable but the air tightness of the connections in the present form is not good enough. As leakage leads to lower efficiencies focus should be put on making the connections more air tight without loosing the easiness in connecting the solar air collectors. As a spin off of the project a simple and easy way to determine the efficiency of solar, air collectors for pre-heating of fresh air has been validated. The simple method of determining the efficiency has with success been compared with an advance method

  12. Toxicity assessment due to sub-chronic exposure to individual and mixtures of four toxic heavy metals

    Energy Technology Data Exchange (ETDEWEB)

    Cobbina, Samuel J.; Chen, Yao [School of the Environment, Jiangsu University, Xuefu Rd. 301, Zhenjiang 212013, Jiangsu (China); Zhou, Zhaoxiang; Wu, Xueshan; Zhao, Ting [School of Chemistry and Chemical Engineering, Jiangsu University, Xuefu Rd. 301, Zhenjiang 212013 (China); Zhang, Zhen [School of the Environment, Jiangsu University, Xuefu Rd. 301, Zhenjiang 212013, Jiangsu (China); Feng, Weiwei; Wang, Wei [School of Food and Biological Engineering, Jiangsu University, Xuefu Rd. 301, Zhenjiang 212013, Jiangsu (China); Li, Qian [School of Pharmacy, Jiangsu University, Xuefu Rd. 301, Zhenjiang 212013, Jiangsu (China); Wu, Xiangyang, E-mail: wuxy@ujs.edu.cn [School of the Environment, Jiangsu University, Xuefu Rd. 301, Zhenjiang 212013, Jiangsu (China); Yang, Liuqing, E-mail: yangliuqing@ujs.edu.cn [School of Chemistry and Chemical Engineering, Jiangsu University, Xuefu Rd. 301, Zhenjiang 212013 (China)

    2015-08-30

    Highlights: • Low dose single and mixtures of toxic metals had adverse effect on mice. • Metal mixtures exhibited higher toxicities compared to individual metals. • Mixtures of low dose Pb + Hg + Cd induced neuronal degeneration in brain of mice. • Exposure to Pb + Hg + As + Cd showed renal tubular necrosis in kidney. - Abstract: Humans are exposed to a cocktail of heavy metal toxicants in the environment. Though heavy metals are deleterious, there is a paucity of information on toxicity of low dose mixtures. In this study, lead (Pb) (0.01 mg/L), mercury (Hg) (0.001 mg/L), cadmium (Cd) (0.005 mg/L) and arsenic (As) (0.01 mg/L) were administered individually and as mixtures to 10 groups of 40 three-week old mice (20 males and 20 females), for 120 days. The study established that low dose exposures induced toxicity to the brain, liver, and kidney of mice. Metal mixtures showed higher toxicities compared to individual metals, as exposure to low dose Pb + Hg + Cd reduced brain weight and induced structural lesions, such as neuronal degeneration in 30-days. Pb + Hg + Cd and Pb + Hg + As + Cd exposure induced hepatocellular injury to mice evidenced by decreased antioxidant activities with marginal increases in MDA. These were accentuated by increases in ALT, AST and ALP. Interactions in metal mixtures were basically synergistic in nature and exposure to Pb + Hg + As + Cd induced renal tubular necrosis in kidneys of mice. This study underlines the importance of elucidating the toxicity of low dose metal mixtures so as to protect public health.

  13. Illegal Dumping of Toxic Waste and Its Effect on Human Health in Campania, Italy

    Directory of Open Access Journals (Sweden)

    Alfredo Mazza

    2015-06-01

    Full Text Available The region of Campania (particularly Naples and Caserta has experienced an emergency in the waste management cycle during past years. Although the most critical phase has been overcome after the construction of the incineration plant in Acerra (an old-fashioned technology built up over a few months, whose impact on environment and health has not yet been assessed, most of the underlying problems have not been resolved. The illegal burning of wheels, plastics, textiles, and other industrial residuals, along with the detection of two thousand toxic substance dumping sites, still represents major concerns of environmental pollution and population health. This review summarizes the most relevant studies, which analyzed chemical contamination (primarily dioxins and polychlorinated biphenyls (PCBs of the air, soil, water, animals, and humans in Campania. In addition, we reviewed information on population health (i.e., mortality data, congenital malformations, and cancer incidence. Moving from a detailed mapping of (mostly illegal waste dumping sites in Campania, we have focused on recent studies which have found: (a high concentrations of dioxins (≥5.0 pg TEQ/g fat in milk samples from sheep, cows, and river buffaloes; (b remarkable contamination of dioxin and PCBs in human milk samples from those living in the Naples and Caserta areas (PCDDs+PCDFs and dioxin-like-PCBs (dl-PCBs assessed at 16.6 pg TEQ/g of fat; range: 7.5–43 pg/g of fat; (c potential age-adjusted standardized mortality rates associated with some specific cancer types; (d a statistically significant association between exposure to illegal toxic waste dumping sites and cancer mortality, even after adjustment by socio-economic factors and other environmental indicators.

  14. Illegal Dumping of Toxic Waste and Its Effect on Human Health in Campania, Italy.

    Science.gov (United States)

    Mazza, Alfredo; Piscitelli, Prisco; Neglia, Cosimo; Della Rosa, Giulia; Iannuzzi, Leopoldo

    2015-06-16

    The region of Campania (particularly Naples and Caserta) has experienced an emergency in the waste management cycle during past years. Although the most critical phase has been overcome after the construction of the incineration plant in Acerra (an old-fashioned technology built up over a few months, whose impact on environment and health has not yet been assessed), most of the underlying problems have not been resolved. The illegal burning of wheels, plastics, textiles, and other industrial residuals, along with the detection of two thousand toxic substance dumping sites, still represents major concerns of environmental pollution and population health. This review summarizes the most relevant studies, which analyzed chemical contamination (primarily dioxins and polychlorinated biphenyls (PCBs)) of the air, soil, water, animals, and humans in Campania. In addition, we reviewed information on population health (i.e., mortality data, congenital malformations, and cancer incidence). Moving from a detailed mapping of (mostly illegal) waste dumping sites in Campania, we have focused on recent studies which have found: (a) high concentrations of dioxins (≥5.0 pg TEQ/g fat) in milk samples from sheep, cows, and river buffaloes; (b) remarkable contamination of dioxin and PCBs in human milk samples from those living in the Naples and Caserta areas (PCDDs+PCDFs and dioxin-like-PCBs (dl-PCBs) assessed at 16.6 pg TEQ/g of fat; range: 7.5-43 pg/g of fat); (c) potential age-adjusted standardized mortality rates associated with some specific cancer types; (d) a statistically significant association between exposure to illegal toxic waste dumping sites and cancer mortality, even after adjustment by socio-economic factors and other environmental indicators.

  15. Human and environmental impact assessment of postcombustion CO2 capture focusing on emissions from amine-based scrubbing solvents to air.

    Science.gov (United States)

    Veltman, Karin; Singh, Bhawna; Hertwich, Edgar G

    2010-02-15

    Carbon Capture and Storage (CCS) has become a key technology in climate change mitigation programs worldwide. CCS is well-studied in terms of greenhouse gas emission reduction potential and cost of implementation. Impacts on human health and the environment have, however, received considerably less attention. In this work, we present a first assessment of human health and environmental impacts of a postcombustion CO(2) capture facility, focusing on emissions from amine-based scrubbing solvents and their degradation products to air. We develop characterization factors for human toxicity for monoethanolamine (MEA) as these were not yet available. On the basis of the limited information available, our assessment indicates that amine-based scrubbing results in a 10-fold increase in toxic impact on freshwater ecosystems and a minor increase in toxic impacts on terrestrial ecosystems. These increases are attributed to emissions of monoethanolamine. For all other impact categories, i.e., human toxicity, marine ecotoxicity, particulate matter formation, photochemical oxidant formation, and terrestrial acidification, the CO(2) capture facility performs equally well to a conventional NGCC power plant, albeit substantial changes in flue gas composition. The oxidative degradation products of MEA, i.e., formaldehyde, acetaldehyde, and ammonia, do not contribute significantly to total environmental impacts.

  16. Recreational Use, Analysis and Toxicity of Tryptamines

    Science.gov (United States)

    Tittarelli, Roberta; Mannocchi, Giulio; Pantano, Flaminia; Romolo, Francesco Saverio

    2015-01-01

    The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a “legal” alternative to internationally controlled drugs. There are many categories of NPS, such as synthetic cannabinoids, synthetic cathinones, phenylethylamines, piperazines, ketamine derivatives and tryptamines. Tryptamines are naturally occurring compounds, which can derive from the amino acid tryptophan by several biosynthetic pathways: their structure is a combination of a benzene ring and a pyrrole ring, with the addition of a 2-carbon side chain. Tryptamines include serotonin and melatonin as well as other compounds known for their hallucinogenic properties, such as psilocybin in ‘Magic mushrooms’ and dimethyltryptamine (DMT) in Ayahuasca brews. Aim: To review the scientific literature regarding tryptamines and their derivatives, providing a summary of all the available information about the structure of these compounds, their effects in relationship with the routes of administration, their pharmacology and toxicity, including articles reporting cases of death related to intake of these substances. Methods: A comprehensive review of the published scientific literature was performed, using also non peer-reviewed information sources, such as books, government publications and drug user web fora. Conclusions: Information from Internet and from published scientific literature, organized in the way we proposed in this review, provides an effective tool for specialists facing the emerging NPS threat to public health and public security, including the personnel working in Emergency Department. PMID:26074742

  17. Toxic effects of domestic sewage on zooplankton

    Digital Repository Service at National Institute of Oceanography (India)

    Gajbhiye, S.N.; Nair, V.R.; Desai, B.N.

    The toxic effects of raw domestic sewage on different groups of zooplank-ton, was tested in the laboratory for evaluating acute toxicity. 24 hr., LC-50 values for larvae of stomatopods, gastropods and chaetognaths (2-7% concentration) indicated...

  18. Burning up TNF toxicity for cancer therapy

    OpenAIRE

    Leist, Marcel; Jäättelä, Marja

    2002-01-01

    The tumor-killing capacity and the systemic toxicity of the cytokine tumor necrosis factor (TNF) have appeared inseparable. Now a study shows that TNF loses its toxicity but still kills tumors in heat-treated mice.

  19. Air quality management planning (AQMP

    Directory of Open Access Journals (Sweden)

    Sivertsen Bjarne

    2012-01-01

    Full Text Available In most urban areas of the world, particulate matter (PM levels pose severe problems, addressed in several policy areas (air quality, climate change, and human health. PM presents multiple challenges due to the multitude of its sources, spanning many sectors of economic activity as well as nature, and due to the complexity of atmospheric processes involved in its transport and secondary formation. For the authorities, the goal is to assure minimal impacts of atmospheric PM levels, in practice represented by compliance with existing regulations and standards. This may be achieved through an air quality management plan (AQMP. In Northern America and in parts of Europe, comprehensive research programs have guided development of AQMP over the last forty years. This cumulated experience can be utilized by others who face the same problems, but have yet to develop their own substantial research base. The main purpose of the AQMP development process is to establish an effective and sound basis for planning and management of air quality in a selected area. This type of planning will ensure that significant sources of impacts are identified and controlled in a most cost-effective manner. The choice of tools, methods and input information is often dictated by their availability, and should be evaluated against current best practices. Important elements of the AQMP are the identification of sources and development of a complete emission inventory, the development and operation of an air quality monitoring programme, and the development and application of atmospheric dispersion models. Major task is to collect the necessary input data. The development of the AQMP will take into account: - Air Quality Management System (AQMS requirements; - Operational and functional structure requirements; - Source identification through emission inventories; - Source reduction alternatives, which may be implemented; - Mechanisms for facilitating interdepartmental

  20. Cleaner Air for Home and Office

    Science.gov (United States)

    1989-01-01

    Increased insulation has led to higher concentrations in homes and offices of toxic chemicals caused by emissions from synthetic building components. Recent NASA research regarding future interplanetary manned spacecraft has shown that certain plants can absorb gasses, reducing indoor air pollution. After working with water purifying water hyacinths, Dr. B. C. Wolverton at NSTL developed a carbon/plant filter system to remove chemicals, smoke, etc. Two companies have commercialized the system. Bio-safe provides plants, a bed of activated carbon and an air pump installed near the plant's roots. Pollutants are trapped by the charcoal and either digested by the roots or broken down by microorganisms. Purified air is then directed back into the room. Applied Indoor Resource Company markets Bio-Pure, which includes plants on a layer of patented soil medium with activated carbon. Legumes and mosses filter the air; a blower moves air through the filtering system for cleansing by microorganisms. Research at NSTL continues, and the system may eventually be enlarged.