WorldWideScience

Sample records for agrotehnilisi vtteid ida-kitseherne

  1. Galileo photometry of asteroid 243 Ida

    Science.gov (United States)

    Helfenstein, P.; Veverka, J.; Thomas, P.C.; Simonelli, D.P.; Klaasen, K.; Johnson, T.V.; Fanale, F.; Granahan, J.; McEwen, A.S.; Belton, M.; Chapman, C.

    1996-01-01

    Galileo imaging observations over phase angles 19.5?? to 109.8?? are combined with near-opposition Earth-based data to derive the photometric properties of Ida. To first order these properties are uniform over the surface and well modeled at ?? = 0.55 ??m by Hapke parameters ????0 = 0.22, h = 0.020, B0 = 1.5, g = -0.33, and ?? = 18?? with corresponding geometric albedo p = 0.21??0.030.01 and Bond albedo AB = 0.081??0.0170.008. Ida's photometric properties are more similar to those of "average S-asteroids" (P. Helfenstein and J. Veverka 1989, Asteroids II, Univ. of Arizona Press, Tucson) than are those of 951 Gaspra. Two primary color units are identified on Ida: Terrain A exhibits a spectrum with relatively shallower 1-??m absorption and a relatively steeper red spectral slope than average Ida, while Terrain B has a deeper 1-??m absorption and a less steep red slope. The average photometric properties of Ida and Terrain A are similar while those of Terrain B differ mostly in having a slightly higher value of ????0 (0.22 versus 0.21), suggesting that Terrain B consists of slightly brighter, more transparent regolith particles. Galileo observations of Ida's satellite Dactyl over phase angles 19.5?? to 47.6?? suggest photometric characteristics similar to those of Ida, the major difference being Dactyl's slightly lower albedo (0.20 compared to 0.21). ?? 1990 Academic Press, Inc.

  2. Clinical comparison of diisopropyl-IDA Tc 99m and diethyl-IDA Tc 99m for evaluation of the hepatobiliary system

    International Nuclear Information System (INIS)

    Klingensmith, W.C.; Fritzberg, A.R.; Spitzer, V.M.; Kuni, C.C.; Shanahan, W.S.

    1981-01-01

    Thirty-one patients with a wide range of hepatobiliary function and clinical diagnoses were studied with both diisopropyl-IDA Tc 99m and diethyl-IDA Tc 99m. Images were similar except for an increased liver-to-kidney ratio with diisopropyl-IDA Tc 99m (p less than 0.01) and a tendency toward an increased liver-to-background ratio at five minutes with diisopropyl-IDA Tc 99m (p greater than 0.05). Quantification of the relative hepatocyte extraction efficiency indicated a 16% higher extraction efficiency for diisopropyl-IDA Tc 99m (p greater than 0.05). Cumulative three-hour urine collections following injection demonstrated no significant difference in renal excretion in patients with normal total serum bilirubin levels. Both radiopharmaceuticals demonstrated increasing renal excretion with increasing total serum bilirubin levels; however, renal excretion of diisopropyl-IDA Tc 99m increased more slowly than excretion of diethyl-IDA Tc 99m (p less than 0.01). We conclude that, while the overall differences between these two radiopharmaceuticals are small, diisopropyl-IDA Tc 99m is superior because of a lower renal excretion rate in patients with decreased hepatocyte function

  3. Comparative quantitative evaluation of hepatic clearance of diethyl-IDA and para-butyl-IDA in jaundiced and non-jaundiced patients

    International Nuclear Information System (INIS)

    Tarolo, G.L.; Picozzi, R.; Palagi, B.; Cammelli, F.; Ospedale di Saronno

    1981-01-01

    A method for comparative measurement of hepatic clearance of different hepatobiliary agents is described and the clinical use of diethyl-IDA and parabutyl-IDA is discussed. The study was performed with both radiopharmaceuticals in 13 patients with hepatobiliary disease with serum bilirubin ranging from 0.3 to 16.4 mg/100 ml. Diethyl-IDA is preferable for a qualitative evaluation of hepatobiliary disease because of its higher hepatic clearance and faster biliary excretion rate. Parabutyl-IDA is superior for measuring the hepatocytic uptake function, due to the low urinary excretion and the absence of an apparent re-entry from liver to plasma, even in patients with obstructive jaundice. In contrast, an appreciable re-entry can be demonstrated for diethyl-IDA. (orig.)

  4. Development and Validation of New Anxiety and Bipolar Symptom Scales for an Expanded Version of the IDAS (The IDAS-II)

    Science.gov (United States)

    Watson, David; O'Hara, Michael W.; Naragon-Gainey, Kristin; Koffel, Erin; Chmielewski, Michael; Kotov, Roman; Stasik, Sara M.; Ruggero, Camilo J.

    2012-01-01

    The original Inventory of Depression and Anxiety Symptoms (IDAS) contains 11 nonoverlapping scales assessing specific depression and anxiety symptoms. In creating the expanded version of the IDAS (the IDAS-II), our goal was to create new scales assessing other important aspects of the anxiety disorders as well as key symptoms of bipolar disorder.…

  5. Ida-Virumaa ettevõtete TOP 50

    Index Scriptorium Estoniae

    2005-01-01

    Ilmunud ka: Delovõje Vedomosti-Severo-Vostok 7. sept. lk. 4. Ida-Virumaa ettevõtete TOP 50; Käibe TOP 35; Kasumi TOP 35; Käibe kasvu TOP 20; Kasumi kasvu TOP 20; Rentaabluse TOP 20; Omakapitali tootlikkuse TOP 20; Ida-Virumaa ettevõtete üld- ja finantsandmed

  6. Isotope dilution alpha spectrometry for the determination of plutonium concentration in irradiated fuel dissolver solution : IDAS and R-IDAS

    International Nuclear Information System (INIS)

    Ramaniah, M.V.; Jain, H.C.; Aggarwal, S.K.; Chitambar, S.A.; Kavimandan, V.D.; Almaula, A.I.; Shah, P.M.; Parab, A.R.; Sant, V.L.

    1980-01-01

    The report presents a new technique, Isotope Dilution Alpha Spectrometry (IDAS) and Reverse Isotope Dilution Alpha Spectrometry (R-IDAS) for determining the concentration of plutonium in the irradiated fuel dissolver solution. The method exploits sup(238)Pu in IDAS and sup(239)Pu in R-IDAS as a spike and provides an alternative method to Isotope Dilution Mass Spectrometry (IDMS) which requires enriched sup(242)Pu as a spike. Depending upon the burn-up of the fuel, sup(238)Pu or sup(239)Pu is used as a spike to change the sup(238)Pu/(sup(239)Pu+sup(240)Pu)α activity ratio in the sample by a factor of 10. This change is determined by α-spectrometry on electrodeposited sources using a solid state silicon surface barrier detector coupled to a multichannel analyser. The validity of a simple method based on the geometric progression (G.P.) decrease for the far tail of the spectrum to correct for the tail contribution of sup(238)Pu peak (5.50 MeV) to the low energy sup(239)Pu + sup(240)Pu peak (5.17 MeV) is established. Results for the plutonium concentration on different irradiated fuel dissolver solutions with burn-uo ranging from J,000 to 100,000 MWD/TU are presented and compared with those obtained by IDMS. The values obtained by IDAS or R-IDAS and IDMS agree within 0.5%. (auth.)

  7. Ida-Virumaa ettevõtete TOP aastal 2002

    Index Scriptorium Estoniae

    2003-01-01

    Ettevõtete TOP 55. TOP-i esikümme. Käibe TOP 40. Kasumi TOP 40. Käibe kasvu TOP 20. Kasumi kasvu TOP 20. Rentaabluse TOP 20. Omakapitali tootlikkuse TOP 20. Ida-Virumaa firmade üldandmed. Ida-Virumaa firmade finantsandmed

  8. Ida-Virumaa areneb kõige kiiremini / Sergei Surnin

    Index Scriptorium Estoniae

    Surnin, Sergei

    2006-01-01

    Ilmunud ka: Delovõje Vedomosti 11. okt. lk. 32, Postimees : na russkom jazõke : Nedvizhimost 18. okt. lk. 6. Ida-Virumaa kinnisvaraturu ülevaade. Vt. samas: Ida-Viru eramuturg liigub rahulikumas tempos

  9. Usability evaluation of intradermal adapters (IDA).

    Science.gov (United States)

    Tsals, Izrail

    2017-03-27

    Intradermal adapter device technology minimizes the complexity of the Mantoux technique, thereby providing predictable, reproducible intradermal (ID) injections and removing the concerns regarding the ease and reliability of Mantoux technique when using conventional needle and syringe. The technology employs a simple device with geometry designed to gently deform the skin surface and the subcutaneous tissue, providing the ideal angle and depth of needle insertion for consistently successful intradermal injections. The results of this development were presented at the First, Second and Third Skin Vaccination Summits in 2011, 2013 and 2015 respectively [1,2,3]. The current publication addresses the performance of intradermal adapters (IDA) evaluated in three preclinical studies. The evaluations were based on the assessment of bleb formation in a skin model, an accepted indicator of ID injection success. All evaluated devices share the same proprietary dermal interface technology. Devices instituting this design are easy to use, require minimal training, and employ conventionally molded parts and cannula. These studies evaluated IDAs of initial design integral with luer lock needles, IDAs for use with conventional syringes, and intradermal adapters for use with auto disable syringes (ADID adapters). The evaluated ID adapters were intended to consistently place the lancet of the needle at a depth of 0.75mm from the skin's surface. This placement depth addresses the variation in the skin thickness at immunization sites for the majority of patients independent of many other variables. Most participants preferred the intradermal adapter method over the traditional Mantoux and identified a need for the adapter at their workplace. Evaluation of IDAs by registered nurses indicated these devices increase success of bleb formation. The use of IDA increased the success of forming blebs by about 30%. Nurses felt the injections were much easier to perform, in particular by

  10. Ida and Dactyl: Spectral Reflectance and Color Variations

    Science.gov (United States)

    Veverka, J.; Helfenstein, P.; Lee, P.; Thomas, P.; McEwen, A.; Belton, M.; Klaasen, K.; Johnson, T. V.; Granahan, J.; Fanale, F.; Geissler, P.; Head, J. W., III

    1996-03-01

    Galileo SSI color data between 0.4 and 1.0 μm demonstrate that both Ida and Dactyl are S-type asteroids with similar, but distinct spectra. Small but definite color variations are also observed on Ida itself and involve both the blue part of the spectrum and the depth of the 1-μm pyroxene-olivine band. Ida's surface can be classified into two color terrains: Terrain A has a shallower 1-μm absorption and a steeper visible red slope than does Terrain B. Qualitatively, the color-albedo systematics of these two terrains follow those noted for color units on Gaspra and the variations in 1-μm band depth with weathering described by Gaffeyet al.(Gaffey, M. J., J. F. Bell, R. H. Brown, T. H. Burbine, J. Piatek, K. L. Reed, and D. A. Chaky 1993.Icarus106, 573-602). Terrain A, with its slightly lower albedo, its shallower 1-μm band, and its slightly steeper visible red slope relative to Terrain B could be interpreted as the “more processed,” “more mature,” or the “more weathered” of the two terrains. Consistent with this interpretation is that Terrain A appears to be the ubiquitous background on most of Ida, while Terrain B is correlated with some small craters as well as with possible ejecta from the 10-km Azzurra impact structure. Because of these trends, it is less likely that differences between Terrains A and B are caused by an original compositional inhomogeneity within the body of Ida, although they do fall within the range known to occur within the Koronis family. The spectrum of Dactyl is similar to, but definitely different from, that of Terrain B on Ida. It does not conform to the pattern that obtains between the colors and albedos of Terrains A and B: the satellite's 1-μm band is deeper than that of Terrain B, but its albedo is lower, rather than higher. By itself, the deeper band depth could be interpreted, following Gaffeyet al., to mean that Dactyl is a less weathered version of Terrain B on Ida, but such an interpretation is at odds with

  11. IDAS-RR: an incident data base system for research reactors

    International Nuclear Information System (INIS)

    Matsumoto, Kiyoshi; Kohsaka, Atsuo; Kaminaga, Masanori; Murayama, Youji; Ohnishi, Nobuaki; Maniwa, Masaki.

    1990-03-01

    An Incident Data Base System for Research Reactors, IDAS-RR, has been developed. IDAS-RR has information about abnormal incidents (failures, transients, accidents, etc.) of research reactors in the world. Data reference, input, editing and other functions of IDAS-RR are menu driven. The routine processing and data base management functions are performed by the system software and hardware. PC-9801 equipment was selected as the hardware because of its portability and popularity. IDAS-RR provides effective reference information for the following activities. 1) Analysis of abnormal incident of research reactors, 2) Detail analysis of research reactor behavior in the abnormal incident for building the knowledge base of the reactor emergency diagnostic system for research reactor, 3) Planning counter-measure for emergency situation in the research reactor. This report is a user's manual of IDAS-RR. (author)

  12. GALILEO ORBITER A POS IDA FLYBY TRAJ V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — Galileo Orbiter 60 second sampled trajectory data from the Ida flyby in Ida-centric Solar Ecliptic (ISE) and RTN coordinates. These data cover the interval...

  13. Evaluation of IDA-80 data by the DoD method

    International Nuclear Information System (INIS)

    Beyrich, W.; Golly, W.

    1989-12-01

    The measurement data of 28 interlaboratory analysis performed under the IDA-80 programme are evaluated by the DoD (Distribution of Differences) method with respect to the RSDs of the interlaboratory spreads and the within-laboratory uncertainty components. The resulting estimates are compared to those obtained by variance analysis after application of outlier criteria in the official IDA-80 evaluation. Deviations found in case of the within-laboratory uncertainty components ('run' component of the IDA-80 evaluation) are discussed. (orig./HP) [de

  14. Saksamaa ida kutsub / Thea Karin

    Index Scriptorium Estoniae

    Karin, Thea

    2011-01-01

    Endise Ida-Saksamaa aladel asuvate linnade Dessau-Rosslau ja Chemnitzi (endine Karl-Marx-Stadti) vaatamisväärsustest, s.h UNESCO kultuuripärandisse kuuluvatest Wörlitz-Dessau parkidest ja Bauhausi kompleksist

  15. IDA's Energy Vision 2050

    DEFF Research Database (Denmark)

    Mathiesen, Brian Vad; Lund, Henrik; Hansen, Kenneth

    IDA’s Energy Vision 2050 provides a Smart Energy System strategy for a 100% renewable Denmark in 2050. The vision presented should not be regarded as the only option in 2050 but as one scenario out of several possibilities. With this vision the Danish Society of Engineers, IDA, presents its third...... contribution for an energy strategy for Denmark. The IDA’s Energy Plan 2030 was prepared in 2006 and IDA’s Climate Plan was prepared in 2009. IDA’s Energy Vision 2050 is developed for IDA by representatives from The Society of Engineers and by a group of researchers at Aalborg University. It is based on state......-of-the-art knowledge about how low cost energy systems can be designed while also focusing on long-term resource efficiency. The Energy Vision 2050 has the ambition to focus on all parts of the energy system rather than single technologies, but to have an approach in which all sectors are integrated. While Denmark...

  16. Structures, physicochemical and cytoprotective properties of new oxidovanadium(IV) complexes -[VO(mIDA)(dmbipy)]·1.5H2O and [VO(IDA)(dmbipy)]·2H2O

    Science.gov (United States)

    Drzeżdżon, Joanna; Jacewicz, Dagmara; Wyrzykowski, Dariusz; Inkielewicz-Stępniak, Iwona; Sikorski, Artur; Tesmar, Aleksandra; Chmurzyński, Lech

    2017-09-01

    New oxidovanadium(IV) complexes with a modification of the ligand in the VO2+ coordination sphere were synthesized. [VO(mIDA)(dmbipy)]•1.5H2O and [VO(IDA)(dmbipy)]•2H2O were obtained as dark green crystals and grey-green powder, respectively (mIDA = N-methyliminodiacetic anion, IDA = iminodiacetic anion, dmbipy = 4,4‧-dimethoxy-2,2‧-dipyridyl). The crystal structure of [VO(mIDA)(dmbipy)]·1.5H2O has been determined by the X-ray diffraction method. The studies of structure of [VO(mIDA)(dmbipy)]•1.5H2O have shown that this compound occurs in the crystal as two rotational conformers. Furthermore, the stability constants of [VO(mIDA)(dmbipy)]•1.5H2O and [VO(IDA)(dmbipy)]•2H2O complexes in aqueous solutions were studied by using the potentiometric titration method and, consequently, determined using the Hyperquad2008 program. Moreover, the title complexes were investigated as antioxidant substances. The impact of the structure modification in the VO2+ complexes on the radical scavenging activity has been studied. The ability to scavenge the superoxide radical by two complexes - [VO(mIDA)(dmbipy)]·1.5H2O and [VO(IDA)(dmbipy)]·2H2O was studied by cyclic voltammetry (CV) and nitrobluetetrazolium (NBT) methods. The title complexes were also examined by the spectrophotometric method as scavengers of neutral organic radical - 1,1-diphenyl-2-picrylhydrazyl (DPPH•) and radical cation - 2,2'-azinobis-(3-ethylbenzothiazoline)-6-sulfonic acid (ABTS•+). Furthermore, the biological properties of two oxidovanadium(IV) complexes were investigated in relation to its cytoprotective properties by the MTT and LDH tests based on the hippocampal HT22 neuronal cell line during the oxidative damage induced by hydrogen peroxide. Finally, the results presented in this paper have shown that the both new oxidovanadium(IV) complexes with the 4,4‧-dimethoxy-2,2‧-dipyridyl ligand can be treated as the cytoprotective substances.

  17. Kes kardab Lähis-Ida raha? / Emily Thornton, Stanley Reed

    Index Scriptorium Estoniae

    Thornton, Emily

    2008-01-01

    Lähis-Ida riikide investeerimisfondide tegevusest. Mehed, kes haldavad selle piirkonna riiklikke investeerimisfonde, muudavad Pärsia lahe naftamiljarditega maailma rahanduse palet. Lisa: Hea on olla emiir. Kuuele Lähis-Ida emiraadile kuulub umbes pool kogu maailma riiklike investeerimisfondide varadest

  18. The GSPC: Newest Franchise in al-Qa'ida's Global Jihad

    National Research Council Canada - National Science Library

    Boudali, Lianne K

    2007-01-01

    ... of support in Europe. The alignment of the GSPC with al Qa ida represents a significant change in the group's strategy, however, its decision to join al Qa ida's global jihad should be understood as an act of desperation...

  19. Noortest, tööst ja Ida-Virumaast / Aldis Alus

    Index Scriptorium Estoniae

    Alus, Aldis, 1967-

    2012-01-01

    Sisekaitseakadeemia politsei- ja piirivalvekolledži lõpetanu Julia Vesjolkina lõputööst: "Sisekaitseakadeemia lõpetanud kadettide valmisolek asuda tööle Ida-Virumaale" (2012); juhendaja Piret Teppan. Politsei- ja Piirivalveameti Ida prefekti selgitused prefektuuri personalipoliitika kohta

  20. Hansa Ida-Euroopa fond edetabelis teist kuud jutti esimene / Annika Matson

    Index Scriptorium Estoniae

    Matson, Annika, 1976-

    2005-01-01

    Ajakirja The Wall Street Journal Europe Ida-Euroopa ja Venemaa avatud investeerimisfondide edetabelit juhib teist kuud Hansa Ida-Euroopa Aktsiafond. Tabel: Eesti fond juhib The Wall Street Journali edetabelit

  1. Serum protein-binding ability of sup(99m)Tc-diethyl IDA and sup(99m)Tc-para-butyl IDA studied by electrophoresis and precipitation experiments

    International Nuclear Information System (INIS)

    Sawas-Dimopoulou, C.; Simitzis, G.; Papanicolaou, N.

    1982-01-01

    The aim of the study was to separate and to identify by electrophoresis the proteins which are able to bind 99mTc-diethyl IDA and 99mTc-p-butyl IDA when these radiopharmaceuticals are incubated in vitro with human serum. The determinations were completed by precipitation experiments. Electrophoresis showed that both radiopharmaceuticals have negative charge and move to the anode like organic anions. And it is known that organic anions can interact with cationic groups on the albumin. Moreover, it is generally accepted that the extent to which a drug is bound to a particular protein depends on the concentration of the drug. Consequently, the logical hypothesis that binding of each radiopharmaceutical to the various serum proteins could be easier demonstrated on autoradiographies and electrophoregrams by high concentrations of 99mTc-diethyl IDA and 99mTc-parabutyl IDA in the incubation medium was put to trial

  2. Ida-Virus õppivad narkokoerad avastasid uimasteid

    Index Scriptorium Estoniae

    2005-01-01

    Ilmunud ka: Severnoje Poberezhje 30. juuli lk 4. 21 narkokoera koos koerajuhtidega kõigist politseiprefektuuridest, piirivalvest, maksu- ja tolliametist ning vanglate ametist osalesid IdaVirumaal toimunud koolitusel

  3. Ida-Virumaa keskkond saab 16,5 miljonit krooni / Külli Kriis

    Index Scriptorium Estoniae

    Kriis, Külli, 1961-

    2005-01-01

    Ilmunud ka: Severnoje Poberezhje 16. veebr. lk. 4. Keskkonnainvesteeringute keskuse (KIK) nõukogu otsustas keskkonnaprogrammi esimese vooru projektide rahastamise, mille järgi Ida-Virumaa saab üle 16 miljoni krooni. Tabel: Keskkonnaraha Ida-Virumaale

  4. Further Validation of the IDAS: Evidence of Convergent, Discriminant, Criterion, and Incremental Validity

    Science.gov (United States)

    Watson, David; O'Hara, Michael W.; Chmielewski, Michael; McDade-Montez, Elizabeth A.; Koffel, Erin; Naragon, Kristin; Stuart, Scott

    2008-01-01

    The authors explicated the validity of the Inventory of Depression and Anxiety Symptoms (IDAS; D. Watson et al., 2007) in 2 samples (306 college students and 605 psychiatric patients). The IDAS scales showed strong convergent validity in relation to parallel interview-based scores on the Clinician Rating version of the IDAS; the mean convergent…

  5. Erosion and Ejecta Reaccretion on 243 Ida and Its Moon

    Science.gov (United States)

    Geissler, Paul; Petit, Jean-Marc; Durda, Daniel D.; Greenberg, Richard; Bottke, William; Nolan, Michael; Moore, Jeffrey

    1996-03-01

    Galileo images of Asteroid 243 Ida and its satellite Dactyl show surfaces which are dominantly shaped by impact cratering. A number of observations suggest that ejecta from hypervelocity impacts on Ida can be distributed far and wide across the Ida system, following trajectories substantially affected by the low gravity, nonspherical shape, and rapid rotation of the asteroid. We explore the processes of reaccretion and escape of ejecta on Ida and Dactyl using three-dimensional numerical simulations which allow us to compare the theoretical effects of orbital dynamics with observations of surface morphology. The effects of rotation, launch location, and initial launch speed are first examined for the case of an ideal triaxial ellipsoid with Ida's approximate shape and density. Ejecta launched at low speeds (V≪Vesc) reimpact near the source craters, forming well-defined ejecta blankets which are asymmetric in morphology between leading and trailing rotational surfaces. The net effect of cratering at low ejecta launch velocities is to produce a thick regolith which is evenly distributed across the surface of the asteroid. In contrast, no clearly defined ejecta blankets are formed when ejecta is launched at higher initial velocities (V∼Vesc). Most of the ejecta escapes, while that which is retained is preferentially derived from the rotational trailing surfaces. These particles spend a significant time in temporary orbit around the asteroid, in comparison to the asteroid's rotation period, and tend to be swept up onto rotational leading surfaces upon reimpact. The net effect of impact cratering with high ejecta launch velocities is to produce a thinner and less uniform soil cover, with concentrations on the asteroids' rotational leading surfaces. Using a realistic model for the shape of Ida (P. Thomas, J. Veverka, B. Carcich, M. J. S. Belton, R. Sullivan, and M. Davies 1996,Icarus120, 000-000), we find that an extensive color/albedo unit which dominates the

  6. IDAS, software support for mathematical models and map-based graphics

    International Nuclear Information System (INIS)

    Birnbaum, M.D.; Wecker, D.B.

    1984-01-01

    IDAS (Intermediate Dose Assessment System) was developed for the U.S. Nuclear Regulatory Commission as a hardware/software host for radiological models and display of map-based plume graphics at the Operations Center (HQ), regional incident response centers, and site emergency facilities. IDAS design goals acknowledged the likelihood of future changes in the suite of models and the composition of map features for analysis and graphical display. IDAS provides a generalized software support environment to programmers and users of modeling programs. A database manager process provides multi-user access control to all input and output data for modeling programs. A programmer-created data description file (schema) specifies data field names, data types, legal and recommended ranges, default values, preferred units of measurement, and ''help'' text. Subroutine calls to IDAS from a model program invoke a consistent user interface which can show any of the schema contents, convert units of measurement, and route data to multiple logical devices, including the database. A stand-alone data editor allows the user to read and write model data records without execution of a model. IDAS stores digitized map features in a 4-level naming hierarchy. A user can select the map icon, color, and whether to show a stored name tag, for each map feature. The user also selects image scale (zoom) within limits set by map digitization. The resulting image combines static map information, computed analytic modeling results, and the user's feature selections for display to decision-makers

  7. Lõunaeestlased turgutavad Ida-Virus oma vene keelt / Sirle Sommer Kalda

    Index Scriptorium Estoniae

    Sommer-Kalda, Sirle, 1974-

    2009-01-01

    Euroopa Sotsiaalfondist rahastatava programmi "Keeleõppe arendamine 2007-2010" raames toimunud tööjõuvahetusest, mille käigus kevadel Ida-Virumaa linnade ametnikud ja allasutuste töötajad asusid ajutiselt tööle Lõuna- ja Lääne-Eestis, et parandada oma eesti keele oskust ja lõunaeestlaste vastukülaskäigust Ida-Virumaale vene keele oskuste parandamiseks

  8. A tale of oblivion: Ida Noddack and the ‘universal abundance’ of matter

    Science.gov (United States)

    Santos, Gildo Magalhães

    2014-01-01

    Ida Noddack was a German chemist who in 1925, with her husband Walter Noddack, discovered element 75 (rhenium) and possibly element 43 (technetium). She is also known to have anticipated, by nine years, the possibility of nuclear fission. This article focuses on Ida's hypothesis that all elements are present in any mineral. Ida related the relative abundance of the elements in the Universe to hypothetical properties of the atomic nuclei. This allowed her to speculate about a different Periodic Table in which isotopes might be the cause of unexpected features of periodicity. Ida Noddack faced many professional obstacles because of her scientific nonconformity and gender, the resentment of physicists against intrusion in their field, and the overall difficulty of research under and after the Nazi regime.

  9. Tretjakova, Alavainu ja Johanson tuuritavad Ida-Virumaal

    Index Scriptorium Estoniae

    2004-01-01

    5. apr. alustavad turneed Ida-Virumaal Ave Alavainu ja Tatjana Tretjakova, et esitleda oma luuleraamatut "2keelsed = 2jazõtshnõje" (Kärdla : A. Alavainu, 2004). Jaak Johanson laulab laule nimetatud autorite tekstidele

  10. Substoichiometric IDA in determination of zinc present in some spices (Paper No. RA-14)

    Energy Technology Data Exchange (ETDEWEB)

    Vaidya, M M; Ray, M N

    1982-01-01

    Results of separation and determination of zinc present in four spices, viz. Coriander, King's cumin, Fennel and Fenugreek seeds by IDA are presented. It is observed that zinc could be estimated by substoichiometric extraction as dithiozonate followed by IDA, in spices. The substoichiometric extraction results at lower concentrations of zinc also, but better results are obtained by increasing the concentration of zinc. The substoichiometric IDA agrees fairly with the conventional chemical analysis.

  11. Inglased kavatsevad Ida-Virumaale investeerida / Irina Tokareva

    Index Scriptorium Estoniae

    Tokareva, Irina

    2004-01-01

    Ilmunud ka: Severnoje Poberezhje, 22. okt. 2004, lk. 4. Suurbritannia saatkonna esimehe aset. William Elliott ning tööstus- ja investeeringute jaoskonna assistent Kai Tomasberg viibisid Ida-Virumaal, kus nad veendusid regiooni soodsates investeerimistingimustes

  12. Avatud ja suletud Ida-Euroopa / Anu Allas

    Index Scriptorium Estoniae

    Allas, Anu, 1977-

    2009-01-01

    Näitus "Me näeme teid. Foksali galerii tegevus 1966-1989" Kumu Kunstimuuseumis 20. septembrini. Kuraator Karolina Łabowicz-Dymanus. Kujundaja Jaanus Samma. Lääne ja endise Ida-bloki riikide kunst on eksponeeritud kõrvuti

  13. Obama rahustab murelikku Ida-Euroopat / Jürgen Tamme

    Index Scriptorium Estoniae

    Tamme, Jürgen

    2014-01-01

    USA president Barack Obama puudutas kohtumistel Brüsselis, lisaks olukorrale Krimmis, Euroopa energiajulgeoleku ja Euroopa riikide kaitsekulutuste teemadele, ka NATO kohaloleku suurendamist Ida- ja Kesk-Euroopas

  14. President Ilves kohtus Lähis-Ida oluliste poliitikutega

    Index Scriptorium Estoniae

    2009-01-01

    President Toomas Hendrik Ilves, kes osales Maailma Majandusfoorumi Lähis-Ida piirkondlikul konverentsil, kohtus 15. mail 2009 Jordaania kuninga Abdullah II ja Iraagi asepresidendi Adil Abd Al-Mahdi'ga

  15. Lähis-Ida demokraatia kevad / Saad Eddin Ibrahim

    Index Scriptorium Estoniae

    Ibrahim, Saad Eddin

    2005-01-01

    Demokraatia arengust ja demokraatlike parteide olukorrast Lähis-Idas. Autori sõnul ei saa islamistlikke liikumisi maha suruda ainult jõuga, selle asemel tuleks kasutada poliitilisi reforme. Lisa: Vabaduse tugi

  16. Three Dimensional Spherical Display Systems and McIDAS: Tools for Science, Education and Outreach

    Science.gov (United States)

    Kohrs, R.; Mooney, M. E.

    2010-12-01

    The Space Science and Engineering Center (SSEC) and Cooperative Institute for Meteorological Satellite Studies (CIMSS) at the University of Wisconsin are now using a 3D spherical display system and their Man computer Data Access System (McIDAS)-X and McIDAS-V as outreach tools to demonstrate how scientists and forecasters utilize satellite imagery to monitor weather and climate. Our outreach program displays orbits and data coverage of geostationary and polar satellites and demonstrates how each is beneficial for the remote sensing of Earth. Global composites of visible, infrared and water vapor images illustrate how satellite instruments collect data from different bands of the electromagnetic spectrum to monitor global weather patterns 24 hours a day. Captivating animations on spherical display systems are proving to be much more intuitive than traditional 2D displays, enabling audiences to view satellites orbiting above real-time weather systems circulating the entire globe. Complimenting the 3D spherical display system are the UNIX-based McIDAS-X and Java-based McIDAS-V software packages. McIDAS is used to composite the real-time global satellite data and create other weather related derived products. Client and server techniques used by these software packages provide the opportunity to continually update the real-time content on our globe. The enhanced functionality of McIDAS-V extends our outreach program by allowing in-depth interactive 4-dimensional views of the imagery previously viewed on the 3D spherical display system. An important goal of our outreach program is the promotion of remote sensing research and technology at SSEC and CIMSS. The 3D spherical display system has quickly become a popular tool to convey societal benefits of these endeavors. Audiences of all ages instinctively relate to recent weather events which keeps them engaged in spherical display presentations. McIDAS facilitates further exploration of the science behind the weather

  17. Idas, a Novel Phylogenetically Conserved Geminin-related Protein, Binds to Geminin and Is Required for Cell Cycle Progression*

    Science.gov (United States)

    Pefani, Dafni-Eleutheria; Dimaki, Maria; Spella, Magda; Karantzelis, Nickolas; Mitsiki, Eirini; Kyrousi, Christina; Symeonidou, Ioanna-Eleni; Perrakis, Anastassis; Taraviras, Stavros; Lygerou, Zoi

    2011-01-01

    Development and homeostasis of multicellular organisms relies on an intricate balance between cell proliferation and differentiation. Geminin regulates the cell cycle by directly binding and inhibiting the DNA replication licensing factor Cdt1. Geminin also interacts with transcriptional regulators of differentiation and chromatin remodelling factors, and its balanced interactions are implicated in proliferation-differentiation decisions during development. Here, we describe Idas (Idas being a cousin of the Gemini in Ancient Greek Mythology), a previously uncharacterised coiled-coil protein related to Geminin. We show that human Idas localizes to the nucleus, forms a complex with Geminin both in cells and in vitro through coiled-coil mediated interactions, and can change Geminin subcellular localization. Idas does not associate with Cdt1 and prevents Geminin from binding to Cdt1 in vitro. Idas depletion from cells affects cell cycle progression; cells accumulate in S phase and are unable to efficiently progress to mitosis. Idas protein levels decrease in anaphase, whereas its overexpression causes mitotic defects. During development, we show that Idas exhibits high level expression in the choroid plexus and the cortical hem of the mouse telencephalon. Our data highlight Idas as a novel Geminin binding partner, implicated in cell cycle progression, and a putative regulator of proliferation-differentiation decisions during development. PMID:21543332

  18. Interactive Design of Accelerators (IDA)

    International Nuclear Information System (INIS)

    Barton, M.Q.

    1987-01-01

    IDA is a beam transport line calculation program which runs interactively on an IBM PC computer. It can be used for a large fraction of the usual calculations done for beam transport systems or periods of accelerators or storage rings. Because of the interactive screen editor nature of the data input, this program permits one to rather quickly arrive at general properties of a beam line or an accelerator period

  19. Prantsusmaa silub Ida-Euroopga suhteid / Riina Luik

    Index Scriptorium Estoniae

    Luik, Riina, 1962-

    2004-01-01

    Prantsusmaa peaminister Jean-Pierre Raffarin kohtus Pariisis Ida-Euroopa ajakirjanikega ja rääkis EL-i riikide suhetest ja majanduskoostööst. Vt. samas: Andres Kasekamp. Näpuga viibutamise aeg on möödas. Lisa: Jean-Pierre Raffarin (55)

  20. Using McIDAS-V data analysis and visualization software as an educational tool for understanding the atmosphere

    Science.gov (United States)

    Achtor, T. H.; Rink, T.

    2010-12-01

    The University of Wisconsin’s Space Science and Engineering Center (SSEC) has been at the forefront in developing data analysis and visualization tools for environmental satellites and other geophysical data. The fifth generation of the Man-computer Interactive Data Access System (McIDAS-V) is Java-based, open-source, freely available software that operates on Linux, Macintosh and Windows systems. The software tools provide powerful new data manipulation and visualization capabilities that work with geophysical data in research, operational and educational environments. McIDAS-V provides unique capabilities to support innovative techniques for evaluating research results, teaching and training. McIDAS-V is based on three powerful software elements. VisAD is a Java library for building interactive, collaborative, 4 dimensional visualization and analysis tools. The Integrated Data Viewer (IDV) is a reference application based on the VisAD system and developed by the Unidata program that demonstrates the flexibility that is needed in this evolving environment, using a modern, object-oriented software design approach. The third tool, HYDRA, allows users to build, display and interrogate multi and hyperspectral environmental satellite data in powerful ways. The McIDAS-V software is being used for training and education in several settings. The McIDAS User Group provides training workshops at its annual meeting. Numerous online tutorials with training data sets have been developed to aid users in learning simple and more complex operations in McIDAS-V, all are available online. In a University of Wisconsin-Madison undergraduate course in Radar and Satellite Meteorology, McIDAS-V is used to create and deliver laboratory exercises using case study and real time data. At the high school level, McIDAS-V is used in several exercises in our annual Summer Workshop in Earth and Atmospheric Sciences to provide young scientists the opportunity to examine data with friendly and

  1. Keskerakond võitis Ida-Virus valimised mäekõrguselt / Erik Kalda, Erik Gamzejev

    Index Scriptorium Estoniae

    Kalda, Erik, 1969-

    2007-01-01

    Ilmunud ka: Severnoje Poberezhje, 6. märts 2007, lk. 1,3-4. Ida-Virumaalt pääses Riigikokku neli inimest Kesk- ja kaks Reformierakonnast. Lisa: Hääletamistulemused Ida-Virumaa valimisringkonnas. Vt. samas: Põrujad tunnistavad lüüasaamist

  2. Laiem Lähis-Ida - vapustavad avaldused / Toomas Alatalu

    Index Scriptorium Estoniae

    Alatalu, Toomas, 1942-

    2004-01-01

    Mõiste Laiem Lähis-Ida (Wider Middle East) tähendusest. USA asehalduri Iraagis Paul Bremeri ja USA riigisekretäri Colin Powelli avaldustest USA Iraagist lahkumise ja Iisraeli vägivalla kohta Palestiinas

  3. The pharmacokinetics of Tcsup(99m)-diethyl IDA in hyperferremic mice

    International Nuclear Information System (INIS)

    Sawas-Dimopoulou, C.; Soulpi, C.; Toubanakis, N.

    1985-01-01

    Previously, portal zone fibrosis was observed with deposition of iron in the periportal liver cells and to a lesser extent in the Kupffer cells. Surprisingly, biochemical tests show little disturbance except for a positive BSP test. That would suggest a peculiar sensitivity to iron overload of the important bile excretory pathway including organic anions such as BSP, conjugated bilirubin, dyes and IDA derivatives. The purpose of the present study is to investigate the effect of hyperferremia on the pharmacokinetics of Tcsup(99m)-diethyl IDA. (Auth.)

  4. Ida-Virumaale sisserändamise põhjused pärast Teist maailmasõda / Olaf Mertelsmann

    Index Scriptorium Estoniae

    Mertelsmann, Olaf, 1969-

    2007-01-01

    Sisserändest Ida-Virumaale sõjajärgsel perioodil, umbes aastani 1955. Sisserännet Ida-Virumaale nendel aastatel tingisid sõja mõju, tööjõu puudus, geograafiline asend, põlevkivitööstuse arendamine

  5. Eesti Posti Ida piirkonna keskus tuleb Rakverre / Eda Post

    Index Scriptorium Estoniae

    Post, Eda, 1983-

    2005-01-01

    Eesti Posti nõukogu kiitis heaks ettepaneku moodustada kulude kokkuhoiuks olemasoleva kaheteistkümne asemel viis regionaalset juhtimisüksust - Põhja, Ida, Lõuna, Edela ja Lääne. Lisa: Postiregioonid

  6. Solving the pre-marshalling problem to optimality with A* and IDA*

    DEFF Research Database (Denmark)

    Tierney, Kevin; Pacino, Dario; Voß, Stefan

    2017-01-01

    We present a novel solution approach to the container pre-marshalling problem using the A* and IDA* algorithms combined with several novel branching and symmetry breaking rules that significantly increases the number of pre-marshalling instances that can be solved to optimality. A* and IDA......* are graph search algorithms that use heuristics combined with a complete graph search to find optimal solutions to problems. The container pre-marshalling problem is a key problem for container terminals seeking to reduce delays of inter-modal container transports. The goal of the container pre...

  7. Kesk- ja Ida-Euroopa teel euro poole / Lennart Meri

    Index Scriptorium Estoniae

    Meri, Lennart, 1929-2006

    2007-01-01

    Hypo-Vereinsbank'i konverentsil Münchenis 23. septembril 2004. a. peetud kõne. Eesti vahekord rahaliidu ja euroga, Kesk-Euroopa ja Ida-Euroopa reformiriigid ja nende piirid, Eesti kiire arengu põhjused

  8. Enterogastric reflux detection with technetium-99m IDA

    International Nuclear Information System (INIS)

    Garcia, A.; Pavia, J.; Loomena, F.; Abello, R.; Herranz, R.; Setoain, J.

    1985-01-01

    A Tc-99m IDA scan was performed in a patient with severe alkaline esophagitis subsequent to a Billroth I gastroenterostomy. The scan showed enterogastric reflux simultaneously with gastroesophageal reflux of bile. The study was recorded in a computer and the reflux quantitated

  9. Revision of IRIS/IDA Seismic Station Metadata

    Science.gov (United States)

    Xu, W.; Davis, P.; Auerbach, D.; Klimczak, E.

    2017-12-01

    Trustworthy data quality assurance has always been one of the goals of seismic network operators and data management centers. This task is considerably complex and evolving due to the huge quantities as well as the rapidly changing characteristics and complexities of seismic data. Published metadata usually reflect instrument response characteristics and their accuracies, which includes zero frequency sensitivity for both seismometer and data logger as well as other, frequency-dependent elements. In this work, we are mainly focused studying the variation of the seismometer sensitivity with time of IRIS/IDA seismic recording systems with a goal to improve the metadata accuracy for the history of the network. There are several ways to measure the accuracy of seismometer sensitivity for the seismic stations in service. An effective practice recently developed is to collocate a reference seismometer in proximity to verify the in-situ sensors' calibration. For those stations with a secondary broadband seismometer, IRIS' MUSTANG metric computation system introduced a transfer function metric to reflect two sensors' gain ratios in the microseism frequency band. In addition, a simulation approach based on M2 tidal measurements has been proposed and proven to be effective. In this work, we compare and analyze the results from three different methods, and concluded that the collocated-sensor method is most stable and reliable with the minimum uncertainties all the time. However, for epochs without both the collocated sensor and secondary seismometer, we rely on the analysis results from tide method. For the data since 1992 on IDA stations, we computed over 600 revised seismometer sensitivities for all the IRIS/IDA network calibration epochs. Hopefully further revision procedures will help to guarantee that the data is accurately reflected by the metadata of these stations.

  10. Quantitative Analysis of Homogeneous Electrocatalytic Reactions at IDA Electrodes: The Example of [Ni(PPh2NBn2)2]2+

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Fei; Parkinson, B. A.; Divan, Ralu; Roberts, John; Liang, Yanping

    2016-12-01

    Interdigitated array (IDA) electrodes have been applied to study the EC’ (electron transfer reaction followed by a catalytic reaction) reactions and a new method of quantitative analysis of IDA results was developed. In this new method, currents on IDA generator and collector electrodes for an EC’ mechanism are derived from the number of redox cycles and the contribution of non-catalytic current. And the fractions of bipotential recycling species and catalytic-active species are calculated, which helps understanding the catalytic reaction mechanism. The homogeneous hydrogen evolution reaction catalyzed by [Ni(PPh2NBn2)2]2+ (where PPh2NBn2 is 1,5-dibenzyl-3,7-diphenyl-1,5-diaza-3,7-diphosphacyclooctane) electrocatalyst was examined and analyzed with IDA electrodes. Besides, the existence of reaction intermediates in the catalytic cycle is inferred from the electrochemical behavior of a glassy carbon disk electrodes and carbon IDA electrodes. This quantitative analysis of IDA electrode cyclic voltammetry currents can be used as a simple and straightforward method for determining reaction mechanism in other catalytic systems as well.

  11. Quantitative Analysis of Homogeneous Electrocatalytic Reactions at IDA Electrodes: The Example of [Ni(PPh2NBn2)2]2+

    International Nuclear Information System (INIS)

    Liu, Fei; Parkinson, B.A.; Divan, Ralu; Roberts, John; Liang, Yanping

    2016-01-01

    Interdigitated array (IDA) electrodes have been applied to study the EC’ (electron transfer reaction followed by a catalytic reaction) reactions and a new method of quantitative analysis of IDA results was developed. In this new method, currents on IDA generator and collector electrodes for an EC’ mechanism are derived from the number of redox cycles and the contribution of non-catalytic current. And the fractions of bipotential recycling species and catalytic-active species are calculated, which helps understanding the catalytic reaction mechanism. The homogeneous hydrogen evolution reaction catalyzed by [Ni(P Ph 2 N Bn 2 ) 2 ] 2+ (where P Ph 2 N Bn 2 is 1,5-dibenzyl-3,7-diphenyl-1,5-diaza-3,7-diphosphacyclooctane) electrocatalyst was examined and analyzed with IDA electrodes. Besides, the existence of reaction intermediates in the catalytic cycle is inferred from the electrochemical behavior of a glassy carbon disk electrodes and carbon IDA electrodes. This quantitative analysis of IDA electrode cyclic voltammetry currents can be used as a simple and straightforward method for determining reaction mechanism in other catalytic systems as well.

  12. Ida-Euroopa postkommunistliku kunsti näitus tulemas

    Index Scriptorium Estoniae

    1999-01-01

    Stockholmi uues Moderna Museeti hoones avab kuraatorite kollektiiv 16. okt. 1999 näituse "After the Wall", mis analüüsib Berliini müüri langemise järgset kunstiolukorda ja kultuurimuutusi Ida-Euroopas. Näitusele on valitud eestlastest Inessa Josing, Kai Kaljo, Liina Siib, Jaan Toomik

  13. Ida-Euroopa kunsti meganäitus Stockholmis

    Index Scriptorium Estoniae

    1999-01-01

    Stockholmi Moodsa Kunsti Muuseumis 16. X 1999-16. I 2000 Kesk- ja Ida-Euroopa kunsti näitus 'After the Wall'. Kuraatorid David Elliott, Bojana Pejic, Iris Müller-Westermann. Eestist osalevad Inessa Josing, Kai Kaljo, Liina Siib, Jaan Toomik. Näituse kataloogis on Jaan Kaplinski ja Heie Treieri artiklid, kataloogile tegid koostööd Johannes Saar, Raoul Kurvitz

  14. Metsik ida rahulikus läänes / Annika Koppel

    Index Scriptorium Estoniae

    Koppel, Annika

    2011-01-01

    6.-13. aprillini Saksamaal Wiesbadenis toimunud filmifestivalist "goEast", kus näidati filme Ida- ja Kesk-Euroopast. Festivali peaauhinna sai Andrei Balabanovi film "Katlakütja" (Venemaa), parima režissööri auhinna sai Marian Crisan filmiga "Homme"

  15. 99mTc-diethyl-IDA chloescintigraphy

    International Nuclear Information System (INIS)

    Kim, J. W.; Oh, K. C.; Bae, B. H.; Kim, Y. S.; Park, B. H.

    1981-01-01

    For many years, 131 I-rose bengal has been used as the main hepatobiliary radiopharmaceutical. The undesirable physical characteristics of the radioiodine, however, finally prevented its widespread use in clinical medicine. In recent years, a number of hepatobiliary radiopharmaceuticals employing 99m Tc and 123 I as indicator have been introduced. 99m Tc-diethyl-IDA is a most promising one in these agents. Cholescintigraphy, using 99m Tc-diethyl-IDA was performed in 10 normal subjects and 32 patients suffering from various hepatobiliary disturbances, from Sep. -'79 to Aug-' 80, at the department of radiology, Maryknoll Hospital. The following results are obtained: 1. In normal fasting subjects, the liver, GB, CBD, and the proximal portion of small bowel are clearly delineated within 30 min after the injection. After a fatty meal, the radioactivity of the liver and CBD is notably disappeared with increase of the activity in GB and small bowel. 2. A dilatation of the main biliary ducts is a pathognomomic sign of partial mechanical obstructive disorders and a key point of D.Dx from hepatocellular disorders. 3. In cases of complete biliary obstruction, the radioactivity of the liver, CBD, and small bowel is not separated and the background activity is markedly increased. The kidneys are well visualized. 4. In severe hyperbilirubinaemia of above 10mg%, this method is not valuable

  16. Direct n.c.a. Radioiodination and in-vivo Biologic Behavior of 1251- Dopamine (125IDA) in Mice

    International Nuclear Information System (INIS)

    EI-Sheikht, R.; EL-Ghany, E.A.; EI-Wetery, A.S.; Saleh, Z.A.; Hussien, H.

    2007-01-01

    Dopamine(DA) was successfully labeled with iodine-125 via electrophilic substitution reaction producing 125 IDA tracer. This reaction proceeds well in acidic ph of value equal to 2, due to ease of solubility of the dopamine in this acidic ph value. Two oxidizing agents were used, Chloramine- T and iodogen. At low amount of chloramine-T (25 - 50 μJ) the radiochemical yield of 125 IDA was very low (40 %,) while at 100 μ J, an optimum yield (95 %) was obtained. Also, 20 μJ of iodogen gives a yield of 125 IDA equal to 40 %, while an optimum yield (97%) was obtained at 100 μJ of iodogen. Heating the reaction mixture to 100 degree C for 30 min was recommended to get a yield more than 95%, and heating for long time causes a decomposition of the labeled dopamine. The in-vitro stability of 125 IDA was determined along 24 hours, the data confirms that 125 IDA tracer was stable along eight hours without the detection of any by-products in the reaction mixture. The biodistribution data of the labeled dopamine shows rapid blood clearance, kidneys are the main rout of excretion and thc activity holed by thc kidneys at l/2 hour post injection was 9.5 % which increased gradually to 18.6 % at 1 hour post injection, then passes to the urine which show activity equal to 24.9 % at 2 hours post injection. The labeled dopamine ( 125 IDA) passes through the blood brain barrier (BBB) and the activity detected in the brain was very low and not exceeds 0.2 % at 2 h post injection. The ratio of the uptake of 125 IDA tracer of the brain to the blood was calculated and found equal to 0.1, 0.1, and 0.2 at 1/2, 1, and 2 h post injection, respectively. This low brain to blood ratio due to the low blood clearance of the tracer which males the labeled dopamine not suitable for brain imaging.The 125 IDA tracer was biologically unstable, to some extent, and degraded to free iodine which detected in the thyroid gland at 2 hours post injection with a percentage equal to 3.7

  17. Eri riikide noored üritavad lahendada Ida-Viru probleeme / Ishtvan Ban

    Index Scriptorium Estoniae

    Ban, Ishtvan

    2003-01-01

    Ilmunud ka: Severnoje Poberezhje, 8. aug., lk. 3. Kohtla-Nõmmel programmi 'Euroopa Noored' toetusel toimunud rahvusvahelisest noorte kohtumisest, kus arutati Ida-Virumaa keskkonna ja turismi probleeme

  18. The GSPC: Newest Franchise in al-Qa'ida's Global Jihad

    National Research Council Canada - National Science Library

    Boudali, Lianne K

    2007-01-01

    .... Some observers have speculated that North Africa may be the next safe haven for al Qa ida, and that European countries may face a greater risk of attack if Algerian terrorist groups expand their base...

  19. Reversible adsorption of catalase onto Fe(3+) chelated poly(AAm-GMA)-IDA cryogels.

    Science.gov (United States)

    Aktaş Uygun, Deniz; Uygun, Murat; Akgöl, Sinan; Denizli, Adil

    2015-05-01

    In this presented study, poly(acrylamide-glycidyl methacrylate) [poly(AAm-GMA)] cryogels were synthesized by cryopolymerization technique at sub-zero temperature. Prepared cryogels were then functionalized with iminodiacetic acid (IDA) and chelated with Fe(3+) ions in order produce the metal chelate affinity matrix. Synthesized cryogels were characterized with FTIR, ESEM and EDX analysis, and it was found that the cryogel had sponge like structure with interconnected pores and their pore diameter was about 200 μm. Fe(3+) chelated poly(AAm-GMA)-IDA cryogels were used for the adsorption of catalase and optimum adsorption conditions were determined by varying the medium pH, initial catalase concentration, temperature and ionic strength. Maximum catalase adsorption onto Fe(3+) chelated poly(AAm-GMA)-IDA cryogel was found to be 12.99 mg/g cryogel at 25 °C, by using pH 5.0 acetate buffer. Adsorbed catalase was removed from the cryogel by using 1.0M of NaCl solution and desorption yield was found to be 96%. Additionally, reusability profile of the Fe(3+) chelated poly(AAm-GMA)-IDA cryogel was also investigated and it was found that, adsorption capacity of the cryogels didn't decrease significantly at the end of the 40 reuses. Catalase activity studies were also tested and it was demonstrated that desorbed catalase retained 70% of its initial activity. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Imaging of irradiated liver with Tc-99m-sulfur colloid and Tc-99m-IDA

    International Nuclear Information System (INIS)

    Gelfand, M.J.; Saha, S.; Aron, B.S.

    1981-01-01

    In three cases, irradiated regions of liver failed to concentrate Tc-99m-sulfur colloid. In two of these three, imaging with Tc-99m-acetanilide iminodiacetic acid (IDA) agents within five days showed near normal hepatic uptake of this hepatobiliary imaging agent. The hepatic parenchymal cells may be imaged with Tc-99m-IDA in some irradiated regions of liver, despite loss of reticuloendothelial cell function

  1. Ida and Ardi: The Fossil Cover Girls of 2009

    DEFF Research Database (Denmark)

    Kjærgaard, Peter C.

    2011-01-01

    -million-year-old Ida was promoted as the Eighth Wonder of the World, a Rosetta Stone of palaeontology, the Holy Grail of human evolution. Her 4.4-million-year-old contender was advanced as the Real Thing and won the title as scientific breakthrough of the year. One was supposedly “our earliest ancestor......By the autumn of 2009, contestants for the ultimate prize in the Greatest Show on Earth had narrowed down to two: from Germany, a flat, squirrel-sized lemur-looking creature in artificial resin and glass fibers; and from Ethiopia, a partial, small-brained hominin skeleton. Both had been locked away...... for years, guarded by their sentinels from the curious eyes of the public and from competitors supposedly lurking everywhere. On center stage were Darwinius massilae and Ardipithecus ramidus, or, as they were soon known to palaeontology geeks and breakfast television hosts alike, Ida and Ardi. The 47...

  2. Age differences in IDA savings outcomes: findings from the American Dream Demonstration.

    Science.gov (United States)

    Putnam, Michelle; Sherraden, Michael; Zhang, Lin; Morrow-Howell, Nancy

    2008-01-01

    This study aims to develop a greater understanding of age differences in savings outcomes within Individual Development Accounts (IDAs). Participant data from the American Dream Demonstration (ADD) are examined for age differences in accumulated net deposits, average monthly net deposits, and deposit frequency. ADDprogram data are examined for savings match rates, monthly savings targets, direct deposit, and hours of financial education offered. Results indicate that, on average, older IDA participants have better savings outcomes than younger participants. Findings from this study suggest that impoverished middleaged and older adults can save if provided an opportunity and incentives. However, success will depend on the characteristics of the programs.

  3. IDA Gamma-Ray Laser Annual Summary Report (1990): Investigation of the Feasibility of Developing A Laser Using Nuclear Transitions

    Science.gov (United States)

    1992-04-01

    Broadening in the Theory of Superradiant Emission," Acta Physica Polonica , Vol. A39, 1971, pp. 633-638. 8. B. Balko, I.W. Kay, and J. Neuberger, IDA...Cuopy 1 3 of 60 copies AD-A259 475 IDA PAPER P-2533 IDA GAMMA-RAY LASER ANNUAL SUMMARY REPORT (1990) Investigation of the Feasibility of Developing a ...embody results of major projects which ( a ) have a direct bearing on decisions affecting major programs, (b) address issues of significant concern to

  4. Ida-Euroopa ja soorollid Austrias näitusel / Kati Ilves

    Index Scriptorium Estoniae

    Ilves, Kati, 1984-

    2009-01-01

    Näitus "Soorollid - naiselikkus ja mehelikkus Ida-Euroopa kunstis" ("Gender Check. Feminity and Masculinity in Eastern European Art") Austria moodsa kunsti muuseumis 14. veebruarini 2010. Ekspositsioon algab 1960. aastatega. Kuraator Bojana Pejic. Eestit esindab 11 kunstnikku-rühmitust. Eesti valikust

  5. People in Ida-Virumaa : between two cultures / Ene Must

    Index Scriptorium Estoniae

    Must, Ene

    2002-01-01

    Peamistest probleemidest Ida-Virumaal, Sillamäel ja Narvas. Kohalike elanike seas läbi viidud Eesti sotsioloogide, Eesti integratsioonifondi ja Saar Polli uuringufirma uurimusest, kus uuriti nende sidemeid naaberriikidega, majanduslikku olukorda ning nende võimalikku elukoha muutust seoses majandusliku olukorraga Eestis ja liitumisega EL-iga. Kokkuvõtted uuringu tulemustest. Diagrammid

  6. Effect of phenobarbital on 99mTc-IDA scintigraphy in the evaluation of neonatal jaundice

    International Nuclear Information System (INIS)

    Majd, M.; Reba, R.C.; Altman, R.P.

    1981-01-01

    Hepatobiliary scintigraphy with 99mTc-IDA derivatives was used to evaluate 40 neonates with mixed jaundice. Fourteen patients proved to have biliary atresia. The remaining 26 patients had intrahepatic cholestasis with patent extrahepatic ducts. Sixteen of the 40 patients underwent examinations without phenobarbital stimulation. Sixteen patients had two examinations, one before and one after 3-7 days of phenobarbital therapy. The remaining 8 patients had their initial examinations after phenobarbital therapy. The results of this study show that administration of phenobarbital in a dose of 5 mg/kg/day for at least 5 days prior to the examination enhances and accelerates biliary excretion of IDA compounds and thereby significantly increases the accuracy of 99mTc-IDA scintigraphy in differentiating extrahepatic biliary atresia from neonatal hepatitis. Its routine use in the evaluation of neonatal jaundice is therefore highly recommended

  7. Res Publica Ida-Viru piirkond valis uue juhatuse / Erik Gamzejev

    Index Scriptorium Estoniae

    Gamzejev, Erik, 1967-

    2002-01-01

    Ilmunud ka: Severnoje Poberezhje 4. dets. lk. 1. Res Publica Ida-Viru piirkonna üldkogul valiti uus juhatus, Vladimir Sarantsevi sõnul oli koosolek enamiku Kohtla-Järve osakonna liikmete arvates õigustühine. Res Publica peasekretäri Tõnis Konsi kommentaare

  8. The role of Tc-99m IDA hepatobiliary and Tc-99m colloid hepatic imaging in primary biliary cirrhosis

    International Nuclear Information System (INIS)

    Aburano, T.; Yokoyama, K.; Shuke, N.; Kinuya, S.; Takayama, T.; Tonami, N.; Hisada, K.

    1991-01-01

    To assess the presence of primary biliary cirrhosis, 15 patients at various histopathologic stages were studied by Tc-99m IDA hepatobiliary and/or Tc-99m colloid hepatic imaging. In the earlier stages (I and II), seven of eight patients (88%) showed uniform hepatic retention of Tc-99m IDA. Of seven patients in the same stage, however, four (57%) showed no abnormality on Tc-99m colliod imaging. In three of these four negative patients (75%), uniform hepatic retention of Tc-99m IDA was noted. In the later stages (III and IV), all seven patients showed decreased clearance with or without delayed tracer appearance in the intestine and prominent hepatic retention on Tc-99m IDA imaging; with Tc-99m colloid imaging there was enlargement of the spleen and increased activity in the spleen and bone marrow. Thus, Tc-99m IDA imaging is considered to be more useful in revealing this functional disorder at the earlier stage of primary biliary cirrhosis and in evaluating progression from an earlier to a later stage of disease. Tc-99m colloid imaging also effectively evaluated progression

  9. IDA NOMEX: examination of emergency protective measures in Switzerland; Ueberpruefung der Notfallschutzmassnahmen in der Schweiz. Bericht der interdepartementalen Arbeitsgruppe IDA NOMEX

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-06-15

    This comprehensive report for the Swiss Federal Office of Energy (SFOE) presents the results of work carried out by the Swiss Interdepartmental Working Group on Emergency Protective Measures for Extreme Incidents IDA NOMEX after the nuclear incident in Fukushima, Japan. The first three chapters deal with the initial situation after the incidents in Fukushima. The mandate issued by the Swiss Federal Government to IDA NOMEX and its implementation are discussed. Topics covered include data on the personnel and materials required to deal with nuclear incidents, details with reference to the Swiss Radiation Protection Ordinance, tasks of the various state agencies along with the interfaces between them, lessons learned from the nuclear accident in Fukushima, current deficits in the various organisations and measures to be taken as well as a master plan and its implementation. The testing of the various reference scenarios proposed is discussed and various measures, such as evacuation concepts and the distribution of iodine tablets, are looked at in detail. The international situation is examined and co-operation within Europe and also with international bodies is looked at. Finally the required resources are discussed and further work to be done is looked at. Appendices complete the report.

  10. Ocean-atmosphere dynamics during Hurricane Ida and Nor'Ida: An application of the coupled ocean-;atmosphere–wave–sediment transport (COAWST) modeling system

    Science.gov (United States)

    Olabarrieta, Maitane; Warner, John C.; Armstrong, Brandy N.; Zambon, Joseph B.; He, Ruoying

    2012-01-01

    The coupled ocean–atmosphere–wave–sediment transport (COAWST) modeling system was used to investigate atmosphere–ocean–wave interactions in November 2009 during Hurricane Ida and its subsequent evolution to Nor'Ida, which was one of the most costly storm systems of the past two decades. One interesting aspect of this event is that it included two unique atmospheric extreme conditions, a hurricane and a nor'easter storm, which developed in regions with different oceanographic characteristics. Our modeled results were compared with several data sources, including GOES satellite infrared data, JASON-1 and JASON-2 altimeter data, CODAR measurements, and wave and tidal information from the National Data Buoy Center (NDBC) and the National Tidal Database. By performing a series of numerical runs, we were able to isolate the effect of the interaction terms between the atmosphere (modeled with Weather Research and Forecasting, the WRF model), the ocean (modeled with Regional Ocean Modeling System (ROMS)), and the wave propagation and generation model (modeled with Simulating Waves Nearshore (SWAN)). Special attention was given to the role of the ocean surface roughness. Three different ocean roughness closure models were analyzed: DGHQ (which is based on wave age), TY2001 (which is based on wave steepness), and OOST (which considers both the effects of wave age and steepness). Including the ocean roughness in the atmospheric module improved the wind intensity estimation and therefore also the wind waves, surface currents, and storm surge amplitude. For example, during the passage of Hurricane Ida through the Gulf of Mexico, the wind speeds were reduced due to wave-induced ocean roughness, resulting in better agreement with the measured winds. During Nor'Ida, including the wave-induced surface roughness changed the form and dimension of the main low pressure cell, affecting the intensity and direction of the winds. The combined wave age- and wave steepness

  11. Ocean-atmosphere dynamics during Hurricane Ida and Nor'Ida: An application of the coupled ocean-atmosphere-wave-sediment transport (COAWST) modeling system

    Science.gov (United States)

    Olabarrieta, Maitane; Warner, John C.; Armstrong, Brandy N.; Zambon, Joseph B.; He, Ruoying

    2012-01-01

    The coupled ocean–atmosphere–wave–sediment transport (COAWST) modeling system was used to investigate atmosphere–ocean–wave interactions in November 2009 during Hurricane Ida and its subsequent evolution to Nor’Ida, which was one of the most costly storm systems of the past two decades. One interesting aspect of this event is that it included two unique atmospheric extreme conditions, a hurricane and a nor’easter storm, which developed in regions with different oceanographic characteristics. Our modeled results were compared with several data sources, including GOES satellite infrared data, JASON-1 and JASON-2 altimeter data, CODAR measurements, and wave and tidal information from the National Data Buoy Center (NDBC) and the National Tidal Database. By performing a series of numerical runs, we were able to isolate the effect of the interaction terms between the atmosphere (modeled with Weather Research and Forecasting, the WRF model), the ocean (modeled with Regional Ocean Modeling System (ROMS)), and the wave propagation and generation model (modeled with Simulating Waves Nearshore (SWAN)). Special attention was given to the role of the ocean surface roughness. Three different ocean roughness closure models were analyzed: DGHQ (which is based on wave age), TY2001 (which is based on wave steepness), and OOST (which considers both the effects of wave age and steepness). Including the ocean roughness in the atmospheric module improved the wind intensity estimation and therefore also the wind waves, surface currents, and storm surge amplitude. For example, during the passage of Hurricane Ida through the Gulf of Mexico, the wind speeds were reduced due to wave-induced ocean roughness, resulting in better agreement with the measured winds. During Nor’Ida, including the wave-induced surface roughness changed the form and dimension of the main low pressure cell, affecting the intensity and direction of the winds. The combined wave age- and wave steepness

  12. Saksakeelne kultuuripärand Ida-Euroopas ja selle digiteerimine / Aija Sakova-Merivee

    Index Scriptorium Estoniae

    Sakova-Merivee, Aija, 1980-

    2015-01-01

    Ülevaade 27.–28. aprillini 2015 Saksamaal Regensburgis toimunud rahvusvahelisest seminarist „Saksakeelse kultuuripärandi digiteerimine Ida-Euroopas” (Digitizing German-language cultural heritage from Eastern Europe)

  13. Uus Lähis-Ida / Robert Malley ; tõlk. Märt Väljataga

    Index Scriptorium Estoniae

    Malley, Robert

    2006-01-01

    Lähis-Ida konfliktist ja selle võimalikust edasisest arengust. Sisepoliitilisest olukorrast Palestiinas pärast äärmusrühmituse Hamas valimisvõitu 2006. aasta jaanuaris. Islamiliikumisest Hezbollah

  14. Tööõnnetuste arv Ida-Virus väheneb / Erika Prave

    Index Scriptorium Estoniae

    Prave, Erika, 1970-

    2004-01-01

    Ilmunud ka: Severnoje Poberezhje, 7. dets. 2004, lk. 3. Tööinspektsiooni viimase üheksa aasta statistikast järeldub, et tööõnnetuste arv on Ida-Virumaal aastatega vähenenud peaaegu poole võrra

  15. IDA and the Technical Cooperation Program Real-Time Systems and Ada Workshop, 21-23 June 1988

    Science.gov (United States)

    1988-06-01

    IDA Memorandum Report M-540, IDA and the Technical Cooperation Program Real - Time Systems and Ada Workshop, 21-23 June 1988, documents the results of... time systems , (2) identify and clarify known Ada real-time issues, (3) identify near-term and long-term solutions, and (4) provide assessment and...Technology (ODUSD R&AT). Funding was provided by the STARS Joint Program Office. The objectives were to (1) define requirements for using Ada in real

  16. /sup 99m/Tc-IDA imaging in the differential diagnosis of acute cholecystitis and acute pancreatitis

    International Nuclear Information System (INIS)

    Fonseca, C.; Greenberg, D.; Rosenthall, L.; Arzoumanian, A.; Lisbona, R.

    1979-01-01

    Technetium-/sup 99m/-labelled dimethly-acetanilide-iminodiacetic acid (/sup 99m/Tc-IDA) hepato-biliary imaging was evaluated for its efficacy in distinguishing acute cholecystitis from acute pancreatitis. In a retrospective review, gallbladders were demonstrated by /sup 99m/Tc-IDA in 13 of 15 patients (87%) with acute pancreatitis. This is significantly higher than reports on the frequency of gallbladder filling with oral and intravenous cholangiography in the presence of acute cholecystitis

  17. Ida-Virumaa kunstnike kevadnäitus on kunstimuuseumi filiaalis viimane / Sofja Bauer

    Index Scriptorium Estoniae

    Bauer, Sofia, 1947-2001

    2000-01-01

    Aleksander Igonini korraldatud Ida-Virumaa kunstnike kevadnäitusest Kunstimuuseumi Jõhvi filiaalis, kus 20 kunstnikku olid esitanud 60 tööd, seekordsel näitusel ei osalenud Narva ja Sillamäe kunstnikud

  18. IDA NOMEX: examination of emergency protective measures in Switzerland

    International Nuclear Information System (INIS)

    2012-06-01

    This comprehensive report for the Swiss Federal Office of Energy (SFOE) presents the results of work carried out by the Swiss Interdepartmental Working Group on Emergency Protective Measures for Extreme Incidents IDA NOMEX after the nuclear incident in Fukushima, Japan. The first three chapters deal with the initial situation after the incidents in Fukushima. The mandate issued by the Swiss Federal Government to IDA NOMEX and its implementation are discussed. Topics covered include data on the personnel and materials required to deal with nuclear incidents, details with reference to the Swiss Radiation Protection Ordinance, tasks of the various state agencies along with the interfaces between them, lessons learned from the nuclear accident in Fukushima, current deficits in the various organisations and measures to be taken as well as a master plan and its implementation. The testing of the various reference scenarios proposed is discussed and various measures, such as evacuation concepts and the distribution of iodine tablets, are looked at in detail. The international situation is examined and co-operation within Europe and also with international bodies is looked at. Finally the required resources are discussed and further work to be done is looked at. Appendices complete the report

  19. Kolme ekspeaministri talk-show Ida-Viru ärieliidi ees / Erik Gamzejev

    Index Scriptorium Estoniae

    Gamzejev, Erik, 1967-

    2008-01-01

    Ilmunud ka: Severnoje Poberezhje : Subbota 16. veebr., lk. 1. Majandusminister Juhan Parts, IRL esimees ja parlamendiliige Mart Laar ja Sillamäe sadama ning Silmeti suuraktsionär Tiit Vähi kohtusid Ida-Virumaa suurettevõtete juhtidega. Lisa: Mart Laar; Tiit Vähi; Juhan Parts

  20. Promoting Dark Sky Protection in Chile: the Gabriel Mistral IDA Dark Sky Sanctuary and Other AURA Initiatives

    Science.gov (United States)

    Smith, R. Chris; Smith, Malcolm; Pompea, Stephen; Sanhueza, Pedro; AURA-Chile EPO Team

    2018-01-01

    For over 20 years, AURA has been leading efforts promoting the protection of dark skies in northern Chile. Efforts began in the early 1990s at AURA's Cerro Tololo Inter-American Observatory (CTIO), working in collaboration with other international observatories in Chile including Las Campanas Observatory (LCO) and the European Southern Observatory (ESO). CTIO also partnered with local communities, for example supporting Vicuña's effort to establish the first municipal observatory in Chile. Today we have developed a multifaceted effort of dark sky protection, including proactive government relations at national and local levels, a strong educational and public outreach program, and a program of highlighting international recognition of the dark skies through the IDA Dark Sky Places program. Work on international recognition has included the declaration of the Gabriel Mistral IDA Dark Sky Sanctuary, the first such IDA sanctuary in the world.

  1. Gender Check - veel kord soolisusest Ida-Euroopa kunstis / Mare Tralla

    Index Scriptorium Estoniae

    Tralla, Mare, 1967-

    2010-01-01

    Novembris 2010 Viinis toimunud konverentsist, kus analüüsiti näituse "Gender Check. Feminiinsus ja maskuliinsus Ida-Euroopa kunstis" kogemust ning sellele eelnenud ja järgnenud uurimistöö tulemusi. Esitleti artiklite kogumikku "Gender check: a reader : art and theory in Eastern Europe". "Gender Checki" projekti edasisest saatusest ja mõjust

  2. "Rändur udumere kohal" ehk Ida-Viru maastikke otsides = Travellers above the mist - in search for the landscapes of Ida-Virumaa / Henn Runnel, Rait Parts

    Index Scriptorium Estoniae

    Runnel, Henn, 1983-

    2013-01-01

    Ida-Virumaa maastikest. Tööstusalade rekultiveerimisest ja taaskasutusprojektidest (põlevkivi hariduskeskus, Kiviõli seikluspark, Aidu sõudekanal jm.). Emscheri maastikupargist Saksamaal. Autorite sõnul võiks olemasolevate tööstusmaastike jätkuv kasutus ja nende hilisem rekultiveerimine käia piirkonna hilisemat potensiaali arvestavalt ja kujundavalt. Kaevanduste planeerimisel võiksid osaleda maastikuarhitektid

  3. A Neighborhood Condition for Fractional ID-[A, B]-Factor-Critical Graphs

    Directory of Open Access Journals (Sweden)

    Zhou Sizhong

    2016-05-01

    Full Text Available Let G be a graph of order n, and let a and b be two integers with 1 ≤ a ≤ b. Let h : E(G → [0, 1] be a function. If a ≤ ∑e∋x h(e ≤ b holds for any x ∈ V (G, then we call G[Fh] a fractional [a, b]-factor of G with indicator function h, where Fh = {e ∈ E(G : h(e > 0}. A graph G is fractional independent-set-deletable [a, b]-factor-critical (in short, fractional ID-[a, b]- factor-critical if G − I has a fractional [a, b]-factor for every independent set I of G. In this paper, it is proved that if for any two nonadjacent vertices x, y ∈ V (G, then G is fractional ID-[a, b]-factor-critical. Furthermore, it is shown that this result is best possible in some sense.

  4. The hepatic excretion of 131I-rose bengal and sup(99m)Tc-IDA derivatives in Rotor's syndrome

    International Nuclear Information System (INIS)

    Galli, G.; Focacci, C.; Maini, C.L.; Salvatori, M.; Troncone, L.; Fedeli, G.L.; Rapaccini, G.L.

    1982-01-01

    Bilirubin kinetics and hepatobiliary excretion of some exogenous anions (BSP, 131 I-rose bengal, diethyl and parabutyl-IDA labeled with sup(99m)Tc) were studied in three patients presenting with Rotor's syndrome. Two were brothers; a noja undiced fraternal twin of one of them was also evaluated. The hepatic clearance of the radiopharmaceuticals was imparired in the affected patients but the degree of impairment was different among the tested anions, i.e., maximal for 99 Tc-diethyl-IDA and minimal for 131 I-rose bengal. Parabutyl-IDA was cleared better than the diethyl derivative. The metabolic derangement seems to be the level of transfer from plasma to liver and of the hepatic storage, rather than at the level of hepatocyte excretory pathways, as in the case of Dubin-Johnson syndrome. (orig.)

  5. Stability 'in vivo' and 'in vitro' of the diisopropyl-IDA sup(99m)Tc

    International Nuclear Information System (INIS)

    Verdera, E.S.; Leon, A.S.; Robles, A.M.; Correa, Angela; Oliver, Guillermo; Gamma, Santos; Lanzzeri, Stella; Mitta, A.E.A.

    1982-01-01

    The 'in vitro' and 'in vivo' stability of the diisopropyl (IDA-3) kit in solution and of the molecule labelled with sup(99m)Tc was studied. The following items were studied a) shelf life of the kit in solution b) 'in vitro' stability of the labelled molecule c) distribution and elimination kinetics d) identification and behaviour of the excretion products. Chromatographic control shows 95% yield of labelled product after 20 days storage at 4 deg C and 92% yield after 30 days in the same conditions; biological distribution was good in both cases. Regarding the 'in vitro' stability, no alteration was observed within the 4 hours after its preparation. The stability of the complex was determined by the reaction between sup(99m)TcIDA-3 and DTPA. Analysis by electrophoresis shows the complex to be stable even with DTPA concentrations 5 times higher. Kinetics of distribution and elimination of the labelled molecule, in animals, were afterwards confirmed by sequential scintigraphic images in humans. The excretion of unaltered sup(99m)Tc-IDA by biliary and urinary ways was confirmed by cromatographic and electrophoretic analysis of bladder and gall bladder content and by determination of its biological distribution. (author) [es

  6. Development of a formulation for the preparation of 99m Tc-Ida-bis-Biotin complex

    International Nuclear Information System (INIS)

    Gutierrez B, L.C.

    2000-01-01

    The radiopharmaceuticals of diagnostic use incorporate the radioisotope to an organic or inorganic molecule which goes selectively to the interest organ, to an a physiologic or metabolic process of the body with a simple and quantitatively interpretable kinetics. The 99m Tc occupies 80% from total of the studies realized in the world by the optimum combination of physical half-life (6 h), radionuclide quantity (ng) and high energy emission which allows to obtain results with the greatest information. Actually, in Nuclear Medicine, the research strategies are directed to the use of 'premarkers systems' based in the antibody administration, separated from radionuclide through the use of the avidin/biotin system. According to these considerations it was developed the 99m Tc-IDA-bis-Biotine complex as a new radiopharmaceutical which improves the diagnostic image of infectious core and tumorals. The IDA-biotin compound was synthesised and characterized by its melting point, IR spectroscopy, NMR, MS, UV and High-resolution liquid chromatography (HRLC). With base in an experimental factorial design those variables were established which influence in the radiochemical purity of the radiopharmaceutical which allowed to determine the reaction conditions, pH 9 at environmental temperature (22 Celsius degrees) and the optimum concentrations of the formulation components. IDA-biotine 1.0 mg, stannous chloride 0.1 mg and gluconate 15 mg as weak binding linking were realized to the lyophilized product quality control tests like: stability and radiochemical purity. The analytical techniques used UV spectrophotometry and HRLC were validated. The studies of biodistribution of the 99m Tc-Ida-bis-biotin complex were realized in healthy laboratory animals, showing stability 'In vivo' with renal purification. (Author)

  7. Vene keele trump on Ida-Viru valimisvõitluses rolli kaotamas / Tuuli Koch

    Index Scriptorium Estoniae

    Koch, Tuuli

    2007-01-01

    Ilmunud ka: Postimees : na russkom jazõke 22. veebr. lk. 4. Vaatluse all on Lääne-Virumaa ja Ida-Virumaa kandidaadid parlamendivalimistel. Lisa: Ringkond nr. 6; Ringkond nr. 7. Vt samas: Spiiker ja endine miss hääli püüdmas

  8. Conservation of the abscission signaling peptide IDA during Angiosperm evolution: withstanding genome duplications and gain and loss of the receptors HAE/HSL2

    Directory of Open Access Journals (Sweden)

    Ida M. Stø

    2015-10-01

    Full Text Available The peptide INFLORESCENCE DEFICIENT IN ABSCISSION (IDA, which signals through the leucine-rich repeat receptor-like kinases HAESA (HAE and HAESA-LIKE2 (HSL2, controls different cell separation events in Arabidopsis thaliana. We hypothesize the involvement of this signaling module in abscission processes in other plant species even though they may shed other organs than A. thaliana. As the first step towards testing this hypothesis from an evolutionarily perspective we have identified genes encoding putative orthologues of IDA and its receptors by BLAST searches of publically available protein, nucleotide and genome databases for angiosperms. Genes encoding IDA or IDA-LIKE (IDL peptides and HSL proteins were found in all investigated species, which were selected as to represent each angiosperm order with available genomic sequences. The 12 amino acids representing the bioactive peptide in A. thaliana have virtually been unchanged throughout the evolution of the angiosperms; however, the number of IDL and HSL genes varies between different orders and species. The phylogenetic analyses suggest that IDA, HSL2 and the related HSL1 gene, were present in the species that gave rise to the angiosperms. HAE has arisen from HSL1 after a genome duplication that took place after the monocot - eudicots split. HSL1 has also independently been duplicated in the monocots, while HSL2 has been lost in gingers (Zingiberales and grasses (Poales. IDA has been duplicated in eudicots to give rise to functionally divergent IDL peptides. We postulate that the high number of IDL homologs present in the core eudicots is a result of multiple whole genome duplications. We substantiate the involvement of IDA and HAE/HSL2 homologs in abscission by providing gene expression data of different organ separation events from various species.

  9. Tc-99m-diethyl-IDA imaging: clinical evaluation in jaundiced patients

    International Nuclear Information System (INIS)

    Pauwels, S.; Piret, L.; Schoutens, A.; Vandermoten, G.; Beckers, C.

    1980-01-01

    Hepatobiliary imaging with Tc-99m-N,α-(2,6-diethylacetanilide)-iminodiacetic acid (Tc-diethyl-IDA) was performed in 91 jaundiced patients with documented hepatobiliary damage and serum total bilirubin up to 35 mg/dl. There were 56 patients with obstructive jaundice and 35 with hepatocellular disease. Correct discrimination between hepatocellular and obstructive jaundice was possible with an overall accuracy of 90%. Agreement with the final clinical diagnosis was obtained in 97% of patients with hepatocellular disease, and in 86% of patients with obstructive jaundice. The reliability of the test was inversely related to the serum bilirubin levels below 10 mg/dl to 83% for bilirubin between 10 and 20 mg/dl. Above 20 mg/dl, the demonstration of a mechanical obstruction was possible in only one out of the four patients with obstructive jaundice. The high predictive values of the test illustrate that Tc-diethyl-IDA imaging constitutes a reliable method to demonstrate an obstructive cause for the jaundice as long as the bilirubin level remains below 20 mg/dl

  10. IDA Publications on Irregular Warfare: A Bibliography 2000 - Fall 2008

    Science.gov (United States)

    2008-12-01

    reconstruction effort. D-3550 Non-standard publication UNCLASSIFIED No URL No DTIC accession no. 2008 Memetics – Overview and Baseline Models This report...documents key notions and ideas that collectively com- prise what is known as meme theory or memetics – an emerging area of research for potential...and the dynamics of bio- logical systems as a platform for developing mathematical modes in memetics . D-3599 IDA CRP UNCLASSIFIED Approved for

  11. Ameerika diplomaat käis Ida-Virus suursaadiku visiiti ette valmistamas / Argo Soolep

    Index Scriptorium Estoniae

    Soolep, Argo, 1972-

    2004-01-01

    Ilmunud ka: Severnoje Poberezhje, 24. sept. 2004, lk. 3. Ameerika saatkonna esimene sekretär poliitika ja majanduse küsimuses Stuart A. Dweyer saabus Ida-Virumaale kahepäevasele visiidile. Saatkonna eesmärgiks on külastada kõiki Eesti linnu

  12. Ida-Virus on jäänud vähemaks nii töötuid kui töötajaid / Erik Gamzejev

    Index Scriptorium Estoniae

    Gamzejev, Erik, 1967-

    2007-01-01

    Ilmunud ka: Severnoje Poberezhje, 24. mai 2007, lk. 4. Statistikaameti tööhõiveuuring näitab, et tänavu I kvartalis on Ida-Virus aastatetaguse ajaga võrreldes töötute arv kahanenud 13 700-lt 8500-le. Lisa: Tööturu põhinäitajad Ida-Virumaal

  13. Simultaneous /sup 99m/Tc-p-butyl-IDA and 131I-rose bengal scintigraphy in neonatal jaundice

    International Nuclear Information System (INIS)

    Collier, B.D.; Treves, S.; Davis, M.A.; Heyman, S.; Subramanian, G.; McAfee, J.G.

    1980-01-01

    Eight neonates with jaundice were studied simultaneously with /sup 99m/Tc-p-butyl-IDA and 131 I-rose bengal. Due to physical decay, /sup 99m/Tc-p-butyl-IDA failed to demonstrate delayed excretion through the patent extrahepatic biliary tract in 3 of 5 patients with concomitant hepatitis; 131 I-rose bengal showed small-bowel activity in all 5. Neither agent demonstrated small-bowel activity in 3 neonates with extrahepatic biliary atresia. Based on this clinical trial, 131 I-rose bengal remains the radiopharmaceutical of choice for distinguishing between hepatitis and biliary atresia in these patients

  14. Lähis-Ida sõjalised luulud / Jeffrey D. Sachs ; tõlk. Krister Paris

    Index Scriptorium Estoniae

    Sachs, Jeffrey D.

    2006-01-01

    Käsitledes Lähis-Ida konflikti, ütleb autor, et suur osa iisraellastest ja palestiinlastest näeb konflikti lahendust kahe riigi loomises, kuid probleem on lahenduseni jõudmises. Veerand kummaltki poolt soovib aga täielikku võitu teise üle. USA rollist

  15. Dendrobium okinawense Hatusima & Ida (Orchidaceae: A Newly Recorded Species in Taiwan

    Directory of Open Access Journals (Sweden)

    Shih-Wen Chung

    2007-03-01

    Full Text Available A newly recorded species, Dendrobium okinawense Hatusima & Ida, in Taiwan is described and illustrated. This species is rare and endemic to Ryukyu Islands. We recently found it in the mountains along the coast of southeastern Taiwan. Although the flower of D. okinawense is somewhat structurally similar to that of D. moniliforme, they are evidently different from each other in floral dimension, petals, lip shape and floral color.

  16. Synthesis of 2,6-diisopropyl-phenylcarbamoylmethyl-iminodiacetic acid (DISIDA) and 4-n-p-butyl-phenylcarbamoylmethyl-iminodiacetic acid (BUTYL-IDA). Preparation of lyophilized kit to be used as 99(supm)Tc agent in hepatobiliary system

    International Nuclear Information System (INIS)

    Hamada, E.S.; Barbosa, M.F. de; Theodora, M.A.; Almeida, M. de; Colturato, M.T.; Muramoto, E.; Silva, C.P.G. da.

    1987-08-01

    The synthesis of 2,6 diisopropyl IDA (DISIDA) and 4-n-butyl IDA (BUTIL-IDA) is described. Their spectroscopic properties, radiopharmaceutical preparation and their use as 99 (sup m)Tc complex agent in hepatobiliary studies, are also reported. (Author) [pt

  17. The National Water-Quality Assessment Program Invertebrate Data Analysis System (IDAS) Software: Version 3 (User's Manual)

    National Research Council Canada - National Science Library

    Cuffney, Thomas F

    2003-01-01

    ... as part of the National Water-Quality Assessment Program and stored in the Biological Transactional Database (Bio-TDB). The IDAS software is a stand-alone program for personal computers that run Microsoft...

  18. Eestile väljamakstud ELi toetused ületavad Kesk- ja Ida-Euroopa keskmist / Triin Värav

    Index Scriptorium Estoniae

    Värav, Triin

    2011-01-01

    KPMG Ungari kontori poolt läbiviidud uuringu kokkuvõte "EU Funds in Central and Eastern Europe - Progress report 2007-10" annab ülevaate Kesk- ja Ida-Euroopa rahastamisvahenditest aastateks 2007-2013

  19. Integrated disturbance analysis (IDA): A basis for expert systems in nuclear power plants

    International Nuclear Information System (INIS)

    Bastl, W.

    1987-01-01

    In the framework of a project sponsored by the Bundesminister fur Forschung und Technologie (BMFT) and the Rheinisch-Westfalisches Elektrizitatswerk AG (RWE) the concept of Integrated Disturbance Analysis (IDA) has been developed and applied to the Biblis Unit B Nuclear Power Plant. Rather than using the classical approach, which aims at finding the cause of a plant disturbance, the main goal was to make transparent to the operator what it really means for the process, when a set of parameters begins to deviate from its normal state. Therefore the goal was to help the operator to combine the information on the individual process parameters to the complete picture of the evolving transient, thus facilitating the decision about the importance of a disturbance for operational safety. Considering this goal the most important subjects taken care of were: to extend event sequence analysis by means of analog information; to provide adequate modelling of time dependent processes and feedback loops; to integrate IDA information effectively into the existing control room environment

  20. Comparison of future energy scenarios for Denmark: IDA 2050, CEESA (Coherent Energy and Environmental System Analysis), and Climate Commission 2050

    International Nuclear Information System (INIS)

    Kwon, Pil Seok; Østergaard, Poul Alberg

    2012-01-01

    Scenario-making is becoming an important tool in energy policy making and energy systems analyses. This article probes into the making of scenarios for Denmark by presenting a comparison of three future scenarios which narrate 100% renewable energy system for Denmark in 2050; IDA 2050, Climate Commission 2050, and CEESA (Coherent Energy and Environmental System Analysis). Generally, although with minor differences, the scenarios suggest the same technological solutions for the future such as expansion of biomass usage and wind power capacity, integration of transport sector into the other energy sectors. The methodologies used in two academic scenarios, IDA 2050 and CEESA, are compared. The main differences in the methodologies of IDA 2050 and CEESA are found in the estimation of future biomass potential, transport demand assessment, and a trial to examine future power grid in an electrical engineering perspective. The above-mentioned methodologies are compared in an evolutionary perspective to determine if the methodologies reflect the complex reality well. The results of the scenarios are also assessed within the framework of “radical technological change” in order to show which future scenario assumes more radical change within five dimensions of technology; technique, knowledge, organization, product, and profit. -- Highlights: ► Three future scenarios for Danish future in 2050 are compared. ► All of these scenarios suggest the same solutions for the future with minor differences. ► There are differences in methodologies for IDA 2050 and CEESA such as biomass, transport, and power grid. ► The contents of scenarios are assessed which scenario assume more radical technological change in the future.

  1. EKL osales AIAP/IAA Ida- ja Lääne-Euroopa komitee taasasutamiskonverentsil / Jaan Elken

    Index Scriptorium Estoniae

    Elken, Jaan, 1954-

    2001-01-01

    21.-23. IX toimus Bratislavas AIAP/IAA (Association Internationale des Arts Plastiques - AIAP UNESCO) Euroopa komitee taasasutamiskonverents. Ida-Euroopa komitee juhatuse presidendiks valiti Mehmet Gyleryuz, Lääne-Euroopa komitee presidendiks Werner Schaub. Euroopa IAA kongress toimub Heidelbergis mais 2002 (kaasneval portreenäitusel esindavad Eestit Mall Nukke, Maria-Kristiina Ulas), maailmakongress Ateenas septembris 2002.

  2. User's manual for the National Water-Quality Assessment Program Invertebrate Data Analysis System (IDAS) software, version 5

    Science.gov (United States)

    Cuffney, Thomas F.; Brightbill, Robin A.

    2011-01-01

    The Invertebrate Data Analysis System (IDAS) software was developed to provide an accurate, consistent, and efficient mechanism for analyzing invertebrate data collected as part of the U.S. Geological Survey National Water-Quality Assessment (NAWQA) Program. The IDAS software is a stand-alone program for personal computers that run Microsoft Windows(Registered). It allows users to read data downloaded from the NAWQA Program Biological Transactional Database (Bio-TDB) or to import data from other sources either as Microsoft Excel(Registered) or Microsoft Access(Registered) files. The program consists of five modules: Edit Data, Data Preparation, Calculate Community Metrics, Calculate Diversities and Similarities, and Data Export. The Edit Data module allows the user to subset data on the basis of taxonomy or sample type, extract a random subsample of data, combine or delete data, summarize distributions, resolve ambiguous taxa (see glossary) and conditional/provisional taxa, import non-NAWQA data, and maintain and create files of invertebrate attributes that are used in the calculation of invertebrate metrics. The Data Preparation module allows the user to select the type(s) of sample(s) to process, calculate densities, delete taxa on the basis of laboratory processing notes, delete pupae or terrestrial adults, combine lifestages or keep them separate, select a lowest taxonomic level for analysis, delete rare taxa on the basis of the number of sites where a taxon occurs and (or) the abundance of a taxon in a sample, and resolve taxonomic ambiguities by one of four methods. The Calculate Community Metrics module allows the user to calculate 184 community metrics, including metrics based on organism tolerances, functional feeding groups, and behavior. The Calculate Diversities and Similarities module allows the user to calculate nine diversity and eight similarity indices. The Data Export module allows the user to export data to other software packages (CANOCO, Primer

  3. The clinical pharmacology of technetium diethyl-IDA

    International Nuclear Information System (INIS)

    Tjen, H.S.L.M.

    1979-01-01

    In this presentation the performance of the cholescintigraphic study is evaluated from a patho-physiological point of view. With this approach studies of bilirubin metabolism may also provide important information about the mechanisms whereby other organic compounds are transported, metabolized and excreted by the liver cells. The results indicate that diethyl-IDA is a hepatobiliary agent with excellent biological properties. The behaviour of the reagent in normal and pathological individuals can be correlated to bilirubin metabolism. The performance of the cholescintigraphic study is less dependent on the serum bilirubin level in contrast to routinely used radiologic examinations. The level of alkaline phosphatase and serum transaminases is of no influence to the performance of the examination. Combining serial scintigraphy with time-activity curves and functional images from the computer provides additional information so that a differentiation between parenchymal liver disease and bile duct obstruction can be made. (Auth.)

  4. The radiopharmacological behaviour of Ida-derivatives in normal experimental animals

    International Nuclear Information System (INIS)

    Cox, P.H.

    1981-01-01

    Whilst Technetium-Ida derivatives all show basically similar patterns of biodistribution and as such are suited for cholescintigraphy they nevertheless differ significantly enough from each other to have warranted more detailed comparisons to select the reagent most suited for cholescintigraphy in humans. A review of the basic biological behaviour in animals immediately demonstrates that not only are there observable differences between derivatives but there are also differences in the biological behaviour of any one derivative in different species of animal. Animal data does not therefore directly relate to human biodistribution although many qualitative resemblances can be found. (Auth.)

  5. Juhan Parts tuleb Ida-Virumaale kuulama kohalike inimeste mõtteid / Juhan Parts ; interv. Sergei Stepanov

    Index Scriptorium Estoniae

    Parts, Juhan, 1966-

    2003-01-01

    Ilmunud ka: Severnoje Poberezhje 25. juuli lk. 5, Narvskaja Nedelja 26. juuli lk. 5. 1. ja 2. augustil teeb Eesti Vabariigi peaminister Juhan Parts visiidi Ida-Virumaale, et külastada ettevõtteid, omavalitsusi ja kohtuda inimestega. Peaminister räägib, milliste eesmärkide ja ootustega ta visiidile läheb

  6. Kontrrevolutsioon kontrrevolutsiooni vastu. Tänapäeva Ida-Euroopa / Gaspar Miklos Tamas ; tõlk. Märt Väljataga

    Index Scriptorium Estoniae

    Tamas, Gaspar Miklos

    2008-01-01

    Vastureaktsioonist vasakliberaalse valitsuse poliitikale Ungaris. Nõukogude bloki riikide "reaalne sotsialism" kui riigikapitalismi erivorm. 1989. aasta režiimimuutusest Ida-Euroopa maades, vastupanust neokonservatiivsele kontrrevolutsioonile, idaeurooplaste protestiliikumistele iseloomulikest joontest. Lisa: Ungari filosoof Gaspar Miklos Tamas

  7. Kaug-Ida autoäri eripärast - sae kas või maastur pooleks / Jaanus Piirsalu

    Index Scriptorium Estoniae

    Piirsalu, Jaanus, 1973-

    2010-01-01

    2009. a. tõsteti Venemaal sisseveetavate kasutatud autode tollimakse. Nüüd saetakse Vladivostokki teel olevad kasutatud autod Jaapanis pooleks ja tuuakse üle piiri kui varuosad. Poolitatud autod keevitatakse Vladivostokis taas kokku. Kasutatud autode äri on Kaug-Idas vähenenud kümneid kordi

  8. Venelastest Res Publica toetajad Ida-Virus võivad uuele parteile selja pöörata / Erik Kalda

    Index Scriptorium Estoniae

    Kalda, Erik, 1969-

    2006-01-01

    Ilmunud ka: Severnoje Poberezhje 6. apr. lk. 3, Narvskaja Nedelja 8. apr. lk. 2. Suur osa Ida-Virumaal elavatest Res Publica liikmetest ning toetajatest ei poolda erakonna ühinemist Isamaaliiduga, sest paljude venelaste meelest on Isamaaliit nende huve eirav partei

  9. Evaluation of six new /sup 99m/Tc-IDA agents for hepatobiliary imaging

    Energy Technology Data Exchange (ETDEWEB)

    Chervu, L.R.; Joseph, J.A.; Chun, S.B.; Rolleston, R.E.; Synnes, E.I.; Thompson, L.M.; Aldis, A.E.; Rosenthall, L.

    1988-10-01

    IDA derivatives of three substituted benzothiazol, and two substituted chlorophenyl and one substituted pyrazoline compounds have been labeled with /sup 99m/Tc and screened with four rat models with hepatocellular dysfunction manifesting varying degrees of change of liver architecture and hepatocellular damage associated with an active parenchymal destruction, fatty metamorphosis and cirrhosis. Organ distribution studies at 1 h postinjection have been compared in normal and diseased animal models for each agent labeled with /sup 99m/Tc and with /sup 99m/Tc-Disofenin (Disida) and Lidofenin (Hida) and /sup 131/I-Rose Bengal. From the data obtained with the six new IDA derivatives, the distribution kinetics of /sup 99m/Tc-Arclophenin, (N-N'-2-benzoyl-4-chlorophenyl)carbamoylmethyl) imino diacetic acid (Phenida), are closely comparable to /sup 99m/Tc-Disofenin in all animal models. Crossover patient studies (n = 14) for clinical evaluation of /sup 99m/Tc-Arclophenin vs /sup 99m/Tc-Disofenin indicate the close similarity of the 2 agents with regard to blood pool retention, gross liver/heart ratios and liver washout, suggesting Arclophenin as a suitable agent for hepatobiliary function studies. The impaired hepatocellular animal models presented should serve for fast screening of hepatobiliary agents and enable comparison of a series of closely related compounds.

  10. Life on wood - the carnivorous deep-sea mussel Idas argenteus (Bathymodiolinae, Mytilidae, Bivalvia

    DEFF Research Database (Denmark)

    Ockelmann, Kurt W.; Dinesen, Grete E.

    2011-01-01

    to an ephemeral habitat in the deep sea of both species are described herein. Although larviphagi is known to occur in some filter-feeding bivalves, Idas argenteus is the first mytilid known to be specifically adapted to a carnivorous life. Further, it is argued that the modifications of I. argenteus with regard...... to its shell development, alimentary system, gill anatomy and life habits provide important clues to the evolution of the Bathymodiolinae....

  11. Value of an hepatobiliary imaging agent for diagnosing hepatoma. Example of diethyl-IDA

    Energy Technology Data Exchange (ETDEWEB)

    Bourguet, P; Estable, P; Herry, J Y

    1985-01-01

    A comparative study was performed using two hepatic tracers, a Tc 99m labelled colloid and an hepatobiliary agent Tc 99m labelled diethyl-IDA. In some patients with isolated primary hepatocarcinoma the uptake of the hepatobiliary agent was observed but the colloid was not taken up. In the contrary, the hepatobiliary agent has proved to be of limited value for the diagnosis of hepatomas coexisting with cirrhosis and for the detection of secondary hepatocarcinoma.

  12. Value of an hepatobiliary imaging agent for diagnosing hepatoma. Example of diethyl-IDA

    International Nuclear Information System (INIS)

    Bourguet, P.; Estable, P.; Herry, J.Y.

    1985-01-01

    A comparative study was performed using two hepatic tracers, a Tc 99m labelled colloid and an hepatobiliary agent Tc 99m labelled diethyl-IDA. In some patients with isolated primary hepatocarcinoma the uptake of the hepatobiliary agent was observed but the colloid was not taken up. In the contrary, the hepatobiliary agent has proved to be of limited value for the diagnosis of hepatomas coexisting with cirrhosis and for the detection of secondary hepatocarcinoma [fr

  13. Mürgitankeri jäätmed võivad minna Ida-Virumaale töötlusse / Ingvar Bärenklau

    Index Scriptorium Estoniae

    Bärenklau, Ingvar, 1967-

    2006-01-01

    Mürgitamiskahtlusega tanker Probo Koala võib Paldiski sadamast lahkuda, kui lahendatakse logistikaülesanne, kuidas toimetada ligi 600 kuupmeetrit mürgist vett Paldiskist Ida-Virumaale Vaivara ohtlike jäätmete käitlemise keskusse. Lisa: Probo Koala Eestis

  14. Majandusareng, innovatsioon ja tehnoloogilis-majanduslik paradigma : väljakutse Kesk- ja Ida-Euroopa riikidele / Tarmo Kalvet, Rainer Kattel

    Index Scriptorium Estoniae

    Kalvet, Tarmo, 1975-

    2002-01-01

    Autorid analüüsivad läbiviidud uuringute alusel majanduslikku arengut ning teadus- ja arendustegevust Kesk- ja Ida-Euroopa riikides ning Eestis ja tõdevad, et innovatsioonil põhineva majandussüsteemini jõudmiseks on vaja senisest suuremat riigi toetust.

  15. Professor Jüri Talvetist sai Ida-Lääne akadeemia liige / intervjueerinud Rein Veidemann

    Index Scriptorium Estoniae

    Talvet, Jüri, 1945-

    2011-01-01

    Intervjuu Tartu ülikooli maailmakirjanduse professori Jüri Talvetiga luulefestivalist Curtea de Argeş ("Nopţile de Poezie de la Curtea de Argeş") ja tema rumeenia keelde tõlgitud luulekogust „Unest, lumest” ("De din somn, de din zăpadă" - tõlkija Dumitru M. Ion), mida autor seal esitlemas käis ning Ida-Lääne akadeemiast (Academia Internationala Orient-Occident), mille tegevliikmeks ta valiti

  16. Floral organ abscission peptide IDA and its HAE/HSL2 receptors control cell separation during lateral root emergence.

    Science.gov (United States)

    Kumpf, Robert P; Shi, Chun-Lin; Larrieu, Antoine; Stø, Ida Myhrer; Butenko, Melinka A; Péret, Benjamin; Riiser, Even Sannes; Bennett, Malcolm J; Aalen, Reidunn B

    2013-03-26

    Throughout their life cycle, plants produce new organs, such as leaves, flowers, and lateral roots. Organs that have served their purpose may be shed after breakdown of primary cell walls between adjacent cell files at the site of detachment. In Arabidopsis, floral organs abscise after pollination, and this cell separation event is controlled by the peptide INFLORESCENCE DEFICIENT IN ABSCISSION (IDA), which signals through the leucine-rich repeat receptor-like kinases HAESA (HAE) and HAESA-LIKE2 (HSL2). Emergence of new lateral root primordia, initiated deep inside the root under the influence of auxin, is similarly dependent on cell wall dissolution between cells in the overlaying endodermal, cortical, and epidermal tissues. Here we show that this process requires IDA, HAE, and HSL2. Mutation in these genes constrains the passage of the growing lateral root primordia through the overlaying layers, resulting in altered shapes of the lateral root primordia and of the overlaying cells. The HAE and HSL2 receptors are redundant in function during floral organ abscission, but during lateral root emergence they are differentially involved in regulating cell wall remodeling genes. In the root, IDA is strongly auxin-inducible and dependent on key regulators of lateral root emergence--the auxin influx carrier LIKE AUX1-3 and AUXIN RESPONSE FACTOR7. The expression levels of the receptor genes are only transiently induced by auxin, suggesting they are limiting factors for cell separation. We conclude that elements of the same cell separation signaling module have been adapted to function in different developmental programs.

  17. Use of TC 99-IDA in the differential diagnosis of bile ducts atresia in the newborn

    International Nuclear Information System (INIS)

    Sosky, R.A.; Arias Coehl, S.; Jara York, J.; Calabro, M.A.

    1984-01-01

    Two newborn with jaundice, acholia, coluria, elevated bilirubinemia and alchaline fosfatase were studied at the Nuclear Medicine Unit at the IICS with Tc 99-IDA. Differential diagnosis between bile ducts atresia and neonatal hepatitis can be done with this method. This technique is reliable, low radiation dose to patient and no adverse reaction occurs with this radiopharmaceutical

  18. Observation on the changes of serum erythropoietin (EPO) and ferritin (SF) levels after preserved red cells (PRC) transfusion in patients with iron deficiency anemia (IDA)

    International Nuclear Information System (INIS)

    Li Keqin; Lv Haijun; Li Xinghua

    2008-01-01

    Objective: To study the changes of serum EPO and SF levels after preserved red cells transfusion in patients with IDA. Methods: Serum EPO and SF levels were detected with RIA both before and after transfusing preserved red cells in 35 patients with IDA as well as in 30 controls. Results: Before transfusion serum EPO levels in the patients were significantly higher than those in the controls (P 0.05). Conclusion: Transfusing preserved red cells is an effective treatment and has important role in clinical application. (authors)

  19. Chemical and biological properties of 2,6-diisopropyl IDA labelled with sup(99m)Tc

    International Nuclear Information System (INIS)

    Zmbova, B.; Djokic, D.; Ninkovic, D.; Obradovic, V.; Kostic, K.

    1987-01-01

    A procedure is described for the synthesis of 2,6-diisopropyl IDA (DISIDA) and for preparation of the radiopharmaceutical by ''instant technique''. The chemical parameters affecting the formation of the Sn(II)-DISIDA complex were also determined. Biological studies involved lypophylic measurements, determination of binding constants as well as rate of binding to proteins and biodistribution. Clinical investigation demonstrated good hepatobilliary features of this radiopharmaceutical. (author)

  20. CTC Sentinel. Volume 2, Issue 1, January 2009. Al-Qa’ida’s Five Aspects of Power

    Science.gov (United States)

    2009-01-01

    strategic messaging efforts—the conduit for brand awareness and the expansion of the movement. The distributed social movement that is al-Qa`ida is multi...far beyond message projection and brand awareness efforts. Indeed, the efforts to segment its audience have enabled a far more nuanced messaging

  1. Synthesis and quality control of sup(99m)Tc-p-butyl IDA

    International Nuclear Information System (INIS)

    Zmbova, B.; Konstantinovska-Djokic, D.; Tadzer, I.

    1985-01-01

    A procedure is described for synthesis of p-butyl IDA and for identification of the product by i.r. and NMR spectroscopy and by chemical analysis. A method for preparing this compound by ''instant'' technique and for its labelling with sup(99m)Tc is also given, as well as a procedure for control of the chemical and biological properties of the radiopharmaceutical. Radiochemical study shows a high labelling yield of 95%. Investigation of the biodistribution proves that this preparation is a good hepatobiliary reagent, suitable for use in investigation of the liver functions and for quantitative visualization of the hepatobiliary system. (author)

  2. Mooring observations of the near-inertial wave wake of Hurricane Ida (2009)

    Science.gov (United States)

    Pallàs-Sanz, Enric; Candela, Julio; Sheinbaum, Julio; Ochoa, José

    2016-12-01

    The near-inertial wave wake of Hurricane Ida is examined of the basis of horizontal velocity observations acquired from 7 moorings instrumented with acoustic Doppler current profilers deployed across the shelf break, slope, and at the abyssal plain of the Yucatan Peninsula, from 130 m to ∼3300 m. During the forced stage, background mean-flow consisted on a dominant cyclonic circulation of ∼100 km of diameter intensified toward the Yucatan's shelf (topographic constraint) and bounded by anticyclonic vorticity northeastward (north 25° N). In the low frequency band, subinertial signals of ∈ [5.5-7.5] day period propagating along the Yucatan shelf break. After the passage of Hurricane Ida, energetic near-inertial oscillations spread away from the storm's track over cyclonic vorticity. The wave's Eulerian frequency increases shoreward and toward the Yucatan's shelf. After Ida's passage, mooring data show a contrasting velocity response: semi-diurnal and diurnal tides are enhanced at the shelf break of the Yucatan Peninsula and near-inertial oscillations at the slope and abyssal plain. The near-inertial kinetic energy is largest to the right of the storm track because of the asymmetric wind-stress and amplified due to vorticity trapping near z =-500 m, which is a proxy of the base of the mesoscale structure and where the mean-flow is nearly zero. The blue frequency shifted wave wake propagates downward at ∼57-70 m day-1 and horizontally at 23-28 km day-1 leading a downward vertical energy flux of [1.3-1.6] × 10-2 W m-2. This represents a 7-9% of the total wind power input to near-inertial oscillations that, ultimately, became available for interior ocean mixing. The results suggest that the most energetic wave packet propagated poleward and downward from a broad upwelling region located near the Hurricane's track. The vertical structure of the near-inertial kinetic energy is described as a sum of the first 12 standing vertical modes and as vertically

  3. The IDA cognitive model for the analysis of nuclear power plant operator response under accident conditions. Part I: problem solving and decision making model

    International Nuclear Information System (INIS)

    Smidts, C.; Shen, S.H.; Mosleh, A.

    1997-01-01

    This paper is the first of a series of papers describing IDA which is a cognitive model for analysing the behaviour of nuclear power plant operators under accident conditions. The domain of applicability of the model is a relatively constrained environment where behaviour is significantly influenced by high levels of training and explicit requirement to follow written procedures. IDA consists of a model for individual operator behaviour and a model for control room operating crew expanded from the individual model. The model and its derivatives such as an error taxonomy and data collection approach has been designed with ultimate objective of becoming a quantitative method for human reliability analysis (HRA) in probabilistic risk assessment (PRA). The present paper gives a description of the main components of IDA such as memory structure, goals, and problem solving and decision making strategies. It also identifies factors that are at the origin of transitions between goals or between strategies. These factors cover the effects of external conditions and psychological state of the operator. The description is generic at first and then made specific to the nuclear power plant environment and more precisely to abnormal conditions

  4. 研究炉事故・故障データベースシステム,IDAS-RR; 使用手引書

    OpenAIRE

    松本 潔; 鴻坂 厚夫; 神永 雅紀; 村山 洋二; 大西 信秋; 間庭 正樹

    1990-01-01

    国内外の研究炉の事故・故障に関する情報を収録した研究炉事故・故障データベースシステムIDAS-RR(Incident Data Base System for Research Reactors)を開発した。IDAS-RRは、メニュー形式によってデータの入力、検索、更新、集計処理等、様々な形態の利用が可能なデータベースシステムであり、パーソナルコンピュータPC-9801上で作動する。IDAS-RRは、現在の目的も含め、研究炉を所有する機関に有用なデータベースと考えられる。1)研究炉における事故・故障分析の対象もしくは参考データ、2)研究炉異常診断システムの知識ベース構築のための解析用起因事象参考データ、3)研究炉における緊急時計画の策定の参考データ、本報告書はIDAS-RRの使用手引書である。...

  5. Di case, lingue e finestre: Ida Kaminska, attrice yiddish

    Directory of Open Access Journals (Sweden)

    Giulia Randone

    2015-01-01

    Full Text Available This paper aims to explore the artistic biography of Ida Kaminska – the leading figure of the Yiddish theatre in Poland in the 20th century – proposing a new metaphor for the theatrical experience of the Ashkenazi Jews and a different use of the audio-visual sources. First, I will explain why we can look at the Yiddish theatre as a house (heym with a lot of windows, then I will examine Kaminska’s performance in three different films – On a heym (Without a Home, 1939, Obchod na korze (The Shop on Main Street, 1965 and The Angel Levine (1970 – through this peculiar metaphor. Even if they are not recordings of the theatrical performance, these documents could help us to understand some of the features of Kaminska’s art (i.e., the focus on identity, otherness and Yiddish language and how they changed after the Holocaust.

  6. Keskerakonna Ida-Viru piirkonna juht Eevi Paasmäe: "Mulle meeldib olla otsustamise juures!" / Eevi Paasmäe ; interv. Erik Gamzejev

    Index Scriptorium Estoniae

    Paasmäe, Eevi, 1952-

    2005-01-01

    Ilmunud ka: Severnoje Poberezhje : Subbota 10. sets., lk. 3. Keskerakonna Ida-Viru piirkonna juht lõppenud kohalike valimiste tulemustest, erakonna edust. Arvamust avaldavad Riigikogu spiiker Toomas Varek ja Keskerakonna Jõhvi osakonna juht Villu Pung. Eevi Paasmäe CV

  7. 77 FR 2118 - In the Matter of the Designation of al-Qa'ida Kurdish Battalions (AQKB), Also Known as Kurdistan...

    Science.gov (United States)

    2012-01-13

    ... Battalions (AQKB), Also Known as Kurdistan Brigades, Also Known as Kurdistan Battalion of Islamic State in Iraq, Also Known as Kurdistan Brigade of al-Qaeda in Iraq, as a Specially Designated Global Terrorist... known as al-Qa'ida Kurdish Battalions (AQKB), also known as Kurdistan Brigades, also known as, Kurdistan...

  8. Clearance of sup(99m)Tc-diisopropyl-IDA in the steady state

    Energy Technology Data Exchange (ETDEWEB)

    Karimeddini, M K; Vogler, M A; Spencer, R P

    1984-10-01

    A 77-year-old man with a stent in lace for biliary drainage was examined. Intravenously administered sup(99m)Tc-diisopropyl-IDA showed little accumulation of activity in the abdomen while the stent was draining internally. Upon switching the stent to external drainage, it was possible to monitor the slow movement of the bile which contained radioactivity. Imaging over the liver and comparing activity changes with a sup(99a)Tc standard showed that the decrease in hepatic radioactivity was identical to that occurring in the sup(99m)Tc standard. The liver was thus in a ''steady state'' for excretion of the sup(99m)Tc hepatobiliary agent, for it was extracting as much radioactivity from the circulation as it was excreting.

  9. Jogando a cartada transatlântica: as campanhas anti-linchamento britânicas de Ida B. Wells

    OpenAIRE

    Paisana, Joanne

    2016-01-01

    This paper shows the effectiveness of nineteenth-century transatlantic social campaigns, highlighting the usefulness of using existing reform networks for one black American female agitator in particular, Ida B. Wells. Wells’ 1893 and 1894 British anti-lynching campaigns aimed to raise public awareness and consequently support in Britain for stamping out lynching in America and thereafter to galvanize Americans into doing the same. She was supported by Catherine Impey and temperance campaigne...

  10. The Ongoing Addition of Infrasound Sensors and the Flexette Wind-Noise Reducing System to Global Seismic Network Stations Operated by Project IDA

    Science.gov (United States)

    Ebeling, C. W.; Coon, C.

    2017-12-01

    Infrasound sensors are now being installed at Global Seismic Network (GSN) stations meeting certain infrastructure criteria. Manufactured by Hyperion Technology Group, Inc., these instruments (model IFS-3312) have a nominal sensitivity of 140 mV/Pa (at 1 Hz), a full-scale range of ±100 Pa, and a dynamic range of 120 dB. Low power consumption (750 mW at 12 VDC) and small size (153 mm x 178 mm) ease incorporation into the mix of existing GSN instrumentation. The accompanying flexible rosette ("Flexette") acoustic wind-noise reducing system, designed by Project IDA (International Deployment of Accelerometers-IDA), optimally includes 24 inlets, 4 secondary manifolds, and a single primary manifold. Each secondary manifold is connected to 6 inlets and to the primary manifold by 10-ft air hoses, thus eliminating stresses and the greater potential for leaks associated with the use of pipe. While the main design goal was to maximize the reduction of acoustic wind-noise over the widest range of wind speeds possible, consideration of additional criteria resulted in a Flexette base design easily tailored to meet individual station constraints and restrictions, made up of inexpensive (total cost Marshall Islands), in August 2017. During the next 6 months infrasound capability will be extended to IDA GSN stations BORG (Borganes, Iceland), EFI (Mount Kent, East Falkland Islands), and SACV (Santiago Island, Cape Verde).As with other data from GSN stations, real-time infrasound data are freely available from the Incorporated Research Institutions for Seismology-Data Management Center (IRIS-DMC).

  11. Hepatic blood flow determination. A comparison of 99mTc-diethyl-IDA and indocyanine green as hepatic blood flow indicators in man

    DEFF Research Database (Denmark)

    Henriksen, Jens Henrik Sahl; Winkler, K

    1987-01-01

    99mTc-diethyl-acetanilide-iminodiacetic acid (IDA) was compared with indocyanine green (ICG) as an indicator of hepatic blood flow (HBF). Twelve subjects (8 with cirrhosis, 2 with fatty liver, one with pancreatitis, and one with intestinal angina) were studied during hepatic vein catheterization...

  12. Study on changes of serum ferritin (SF), folic acid (FA) and vitamin B12 levels after transfusion of preserved red cells (PRC) in patients with iron deficiency anemia (IDA)

    International Nuclear Information System (INIS)

    Liu Hongsu; Li Xinhua; Li Keqin

    2008-01-01

    Objective: To explore the changes of serum SF, FA and VitB 12 levels after transfusion of preserved red cells in patients with IDA. Methods: Serum SF, FA and VitB 12 levels (with RIA) were detected both before and after transfusion of preserved red cells in 32 patients with IDA as well as in 35 controls. Results: Before transfusion of preserved red cells, the serum SF levels were significantly lower than those in controls (P 12 levels were significantly higher (P 12 were not much different from those in the controls. Conclusion: Transfusion of preserved red cells proves to be very useful. (authors)

  13. Liquid chromatography, in combination with a quadrupole time-of-flight instrument (LC QTOF), with sequential window acquisition of all theoretical fragment-ion spectra (SWATH) acquisition: systematic studies on its use for screenings in clinical and forensic toxicology and comparison with information-dependent acquisition (IDA).

    Science.gov (United States)

    Roemmelt, Andreas T; Steuer, Andrea E; Poetzsch, Michael; Kraemer, Thomas

    2014-12-02

    Forensic and clinical toxicological screening procedures are employing liquid chromatography-tandem mass spectrometry (LC-MS/MS) techniques with information-dependent acquisition (IDA) approaches more and more often. It is known that the complexity of a sample and the IDA settings might prevent important compounds from being triggered. Therefore, data-independent acquisition (DIA) methods should be more suitable for systematic toxicological analysis (STA). The DIA method sequential window acquisition of all theoretical fragment-ion spectra (SWATH), which uses Q1 windows of 20-35 Da for data-independent fragmentation, was systematically investigated for its suitability for STA. Quality of SWATH-generated mass spectra were evaluated with regard to mass error, relative abundance of the fragments, and library hits. With the Q1 window set to 20-25 Da, several precursors pass Q1 at the same time and are fragmented, thus impairing the library search algorithms to a different extent: forward fit was less affected than reverse fit and purity fit. Mass error was not affected. The relative abundance of the fragments was concentration dependent for some analytes and was influenced by cofragmentation, especially of deuterated analogues. Also, the detection rate of IDA compared to SWATH was investigated in a forced coelution experiment (up to 20 analytes coeluting). Even using several different IDA settings, it was observed that IDA failed to trigger relevant compounds. Screening results of 382 authentic forensic cases revealed that SWATH's detection rate was superior to IDA, which failed to trigger ∼10% of the analytes.

  14. Die Rolle der Grenze in der regionalen Identitätsbildung aus der Sicht der Regionalelite im Südosten und Nordosten Estlands (Setomaa und Ida-Virumaa) / Sigrid Rand

    Index Scriptorium Estoniae

    Rand, Sigrid

    2004-01-01

    Setumaa ja Ida-Virumaa võrdlus, nende Eesti idapoolsete äärealade kohaliku identiteedi kujunemisest ja piiri mõjust sellele. Artikkel tugineb 2002. aastatel tehtud intervjuudele kohaliku võimueliidi esindajatega

  15. Floral organ abscission peptide IDA and its HAE/HSL2 receptors control cell separation during lateral root emergence

    OpenAIRE

    Kumpf, Robert P.; Shi, Chun-Lin; Larrieu, Antoine; Stø, Ida Myhrer; Butenko, Melinka A.; Péret, Benjamin; Riiser, Even Sannes; Bennett, Malcolm J.; Aalen, Reidunn B.

    2013-01-01

    Throughout their life cycle, plants produce new organs, such as leaves, flowers, and lateral roots. Organs that have served their purpose may be shed after breakdown of primary cell walls between adjacent cell files at the site of detachment. In Arabidopsis, floral organs abscise after pollination, and this cell separation event is controlled by the peptide INFLORESCENCE DEFICIENT IN ABSCISSION (IDA), which signals through the leucine-rich repeat receptor-like kinases HAESA (HAE) and HAESA-LI...

  16. Ida-1, the Caenorhabditis elegans orthologue of mammalian diabetes autoantigen IA-2, potentially acts as a common modulator between Parkinson's disease and Diabetes: role of Daf-2/Daf-16 insulin like signalling pathway.

    Science.gov (United States)

    Fatima, Soobiya; Haque, Rizwanul; Jadiya, Pooja; Shamsuzzama; Kumar, Lalit; Nazir, Aamir

    2014-01-01

    The lack of cure to age associated Parkinson's disease (PD) has been challenging the efforts of researchers as well as health care providers. Recent evidences suggest that diabetic patients tend to show a higher future risk for PD advocating a strong correlation between PD and Diabetes, thus making it intriguing to decipher common genetic cues behind these ailments. We carried out studies on ida-1, the C. elegans orthologue of mammalian type-1 diabetes auto-antigen IA-2 towards achieving its functional workup vis-à-vis various associated endpoints of PD and Diabetes. Employing transgenic C. elegans strain expressing "human" alpha synuclein (NL5901) under normal and increased glucose concentrations, we studied aggregation of alpha synuclein, content of dopamine, expression of dopamine transporter, content of reactive oxygen species, locomotor activity, nuclear translocation of FOXO transcription factor Daf-16, and quantification of Daf2/Daf-16 mRNA. Our findings indicate that ida-1 affords protection in the studied disease conditions as absence of ida-1 resulted in higher alpha-synuclein aggregation under conditions that mimic the blood glucose levels of diabetic patients. We also observed reduced dopamine content, decreased motility, defective Daf-16 translocation and reduced expression of Daf-2 and Daf-16. Our studies establish important function of ida-1 as a modulator in Daf-2/Daf-16 insulin like signalling pathway thus possibly being a common link between PD and Diabetes.

  17. Motion of the moonlet in the binary system 243 Ida

    Science.gov (United States)

    Lan, L.; Ni, Y.; Jiang, Y.; Li, J.

    2018-02-01

    The motion of the moonlet Dactyl in the binary system 243 Ida is investigated in this paper. First, periodic orbits in the vicinity of the primary are calculated, including the orbits around the equilibrium points and large-scale orbits. The Floquet multipliers' topological cases of periodic orbits are calculated to study the orbits' stabilities. During the continuation of the retrograde near-circular orbits near the equatorial plane, two period-doubling bifurcations and one Neimark-Sacker bifurcation occur one by one, leading to two stable regions and two unstable regions. Bifurcations occur at the boundaries of these regions. Periodic orbits in the stable regions are all stable, but in the unstable regions are all unstable. Moreover, many quasi-periodic orbits exist near the equatorial plane. Long-term integration indicates that a particle in a quasi-periodic orbit runs in a space like a tire. Quasi-periodic orbits in different regions have different styles of motion indicated by the Poincare sections. There is the possibility that moonlet Dactyl is in a quasi-periodic orbit near the stable region I, which is enlightening for the stability of the binary system.

  18. Geologie des Ida ou Zal (Maroc) Stratigraphie,petrographie et tectonique de la partie SW du bloc occidental du massif ancien du Haut Atlas

    NARCIS (Netherlands)

    Koning, de G.

    1957-01-01

    The present publication deals with the geology of the area known as the Ida ou Zal, situated principally in the Palaeozoic of the Western High Atlas mountains in Morocco. The area extends grosso modo between Argana (N), Sidi Idir (E), Menizla (S) and Tirkou (W); its centre lies at 34°10 N—12°65 W.

  19. The IDA-80 measurement evaluation programme on mass spectrometric isotope dilution analysis of uranium and plutonium. Vol. 3

    International Nuclear Information System (INIS)

    Beyrich, W.; Golly, W.; Spannagel, G.

    1985-04-01

    The evaluation data derived from the measurement results of the laboratories participating in the IDA-80 programme have been compiled in tables and graphs. They concern a total of more than 2000 determinations of isotope ratios, isotope abundances and concentrations for uranium and plutonium obtained on test materials of industrial origin which contained fission products, and on fission product free synthetic reference solutions. Comparisons are made with data certified by CBNM and NBS, and estimates are given which were calculated by variance analyses for within- and between laboratory variations. (orig.) [de

  20. Oriented immobilization of His-tagged kinase RIO1 protein on redox active N-(IDA-like)-Cu(II) monolayer deposited on gold electrode—The base of electrochemical biosensor

    International Nuclear Information System (INIS)

    Mielecki, Marcin; Wojtasik, Justyn; Zborowska, Magdalena; Kurzątkowska, Katarzyna; Grzelak, Krystyna; Dehaen, Wim; Radecki, Jerzy; Radecka, Hanna

    2013-01-01

    Highlights: ► The redox active N-(IDA-like)-Cu(II) monolayer is suitable for oriented and stable immobilization of His-tagged kinase Rio1. ► Cu(II) deposited onto the electrode surface play double role: immobilization sites for His-tagged proteins and transduction centres tracking the protein–small molecule interactions. ► The base of biosensor response towards target compound is the change of Rio1 conformation lading to alternation of the permeability of counter ions to Cu(II) redox centres. -- Abstract: The fabrication of electrochemical biosensor consists of the following successive steps: formation of thiol derivative of iminodiacetic acid (IDA-like/N-heterocyclic donor) and N-acetylcysteamine (NAC) self-assembled monolayer on the Au electrode, complexation of Cu(II) by N(IDA-like) attached to the surface of the Au electrode and immobilization of kinase protein Rio1 through N(IDA-like)-Cu(II)-histidine-tag covalent bond formation. Each step of modification was controlled by cyclic voltammetry, electrochemical impedance spectrometry and atomic force microscopy. The interactions between rHis 6 -Rio1 attached to the surface of the electrode and tyrphostin inhibitor (2E)-N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)-acrylamide (AG-490) and its analogue (2-cyano-N-(4-methoxyphenyl)-3-(pyridin-3-yl)prop-2-enamide) (CPE), present in aqueous solution were monitored with Osteryoung square wave voltammetry. The basis of the biosensor response was the change in the electrochemical properties of Cu(II) redox centres upon formation of the rHis 6 -Rio1-inhibitor complex. A linear responses with high reproducibility and stability were observed between 0.10 and 0.40 μM of AG-490 as well as of CPE. The interaction between rHis 6 -Rio1 and AG-490 was stronger than the interaction with its analogue CPE. Cu(II) redox current decrease of 37.9 ± 1.6% and 23.3 ± 1.0% were observed in the presence of 0.40 μM of AG-490 and CPE, respectively. The presented biosensor could be

  1. "Kui teil on võimalik seda vältida - vältige..." : Nõukogude Liidu poliitika Ida-Euroopas ja külma sõja algus / Kaarel Piirimäe

    Index Scriptorium Estoniae

    Piirimäe, Kaarel

    2004-01-01

    Nõukogude Liidu eesmärkidest Teise maailmasõja järgses Euroopas, rahvademokraatiarežiimide kujundamisest Ida-Euroopa riikides, USA riigisekretäri George Marshalli algatatud Euroopa Taastamise Programmist, Euroopa kommunistlike parteide uue koordinatsioonikeskuse Kominformi asutamiskonverentsist Poolas 1947. a.

  2. The interlaboratory experiment IDA-72 on mass spectrometric isotope dilution analysis. Vol. 2

    International Nuclear Information System (INIS)

    Beyrich, W.; Drosselmeyer, E.

    1975-07-01

    Volume II of the report on the IDA-72 experiment contains papers written by different authors on a number of special topics connected with the preparation, performance and evaluation of the interlaboratory test. In detail the sampling procedures for active samples of the reprocessing plant and the preparation of inactive reference and spike solution from standard material are described as well as new methods of sample conditioning by evaporation. An extra chapter is devoted to the chemical sample treatment as a preparation for mass spectrometric analysis of the U and Pu content of the solutions. Special topics are also methods for mass discrimination corrections, α-spectrometer measurements as a supplement for the determination of Pu-238 and the comparison of concentration determinations by mass spectrometric isotope dilution analysis with those performed by X-ray fluorescence spectrometry. The last part of this volume contains papers connected with the computerized statistical evaluation of the high number of data. (orig.) [de

  3. COSÌ PARLA LA BUONA GIOVINETTA: QUESTIONI DI MORALE E DI LINGUA IN “COME VORREI UNA FANCIULLA” DI IDA BACCINI

    Directory of Open Access Journals (Sweden)

    Rosa Argenziano

    2016-09-01

    Si fornirà quindi una descrizione delle soluzioni linguistiche del testo - con particolare attenzione al rapporto con le scelte manzoniane - opportunamente messe in relazione con l’impostazione pedagogica conservatrice manifestata dalla Baccini, che appare ancora ben lontana dalle idee emancipazioniste abbracciate in seguito. Thus speaks the good damsel: morals and language in “Come vorrei una fanciulla” by Ida Baccini  The post-unification period was a decisive moment in Italian linguistic history, characterized by the gradual and difficult replacement of local dialects with Tuscan-Florentine Italian used by increasingly large numbers of the population, thanks to the synergistic actions of lexicography, educational manuals and children's literature. This paper focuses on a prominent figure in the linguistic and cultural Italianization process: the writer and journalist Ida Baccini (1850-1911. She was the author of pedagogical works for children, among which stands out Le memorie di un pulcino (1875. The paper focuses on one of Baccini’s manuals for the education of young women, a sector which counts numerous late nineteenth century contributions. Come vorrei una fanciulla (1884, like all pedagogical writings of the time, proposed an explicit behavioral model and implicitly conveyed at the same time a specific linguistic style for females. Descriptions of the linguistic solutions in the text - with particular attention on the relationship to Manzonian choices - linked toBaccini’s conservative pedagogical approach, appears very distant from the ideas later embraced by emancipationists.

  4. Infrared coagulation: a preferred option in treating early hemorrhoids Coagulação por raios infravermelhos: opção preferencial para o tratamento de hemorróidas

    Directory of Open Access Journals (Sweden)

    Pravin J. Gupta

    2004-01-01

    Full Text Available BACKGROUND: The ideal therapy for hemorrhoids is always debated. For early grades of the disease, many different modalities of treatment have been proposed. Some are effective but are more painful, others are less painful but their efficacy is not assured on long term. Infrared photocoagulation has emerged as a new addition to the list. In this procedure, the tissue is coagulated by infrared radiation. During treatment, mechanical pressure and radiation energy are applied simultaneously to ablate the blood supply to the hemorrhoidal mass. METHODS: In the present retrospective study, the effect of infrared coagulation on patients with early grades of hemorrhoids is described. In a separate study, a comparison is made between Infrared coagulation and rubber band ligation in terms of their effectiveness and discomfort. RESULTS: 212 patients were treated by infrared coagulation and were followed up for a period of 18 months. Only 28 patients had persistence or recurrence of bleeding. Overall ratio of comfort and patient satisfaction from pain and bleeding was quite satisfactory. The comparative study showed that though rubber band ligation is more effective, it is a more painful procedure. CONCLUSION: These studies shows that Infrared coagulation for hemorrhoids in early stages could prove to be a easy and effective alternative to conventional methods as it is quick, less painful and safe. The procedure can be repeated in case of recurrence and should be considered as the first choice in early hemorrhoids.OBJETIVO: Mostrar os benefícios do uso dos raios infravermelhos como alternativa no tratamento de hemorróidas sangrantes, comparado a outras modalidades habitualmente utilizadas. MÉTODOS: 212 pacientes com hemorróidas sangrantes foram tratados com raios infravermelhos e foram acompanhados por período de 18 meses a fim de se observar os efeitos do procedimento. Comparou-se com outras modalidades usuais de tratamento. RESULTADOS: Apenas 28

  5. Emission of pollutants and the dynamics of air quality in Ida-Viru County in 1995-1998

    International Nuclear Information System (INIS)

    Liblik, Valdo; Kundel, Helmut; Maalma, Kaiu

    1999-01-01

    The organisation of monitoring atmospheric air in Ida-Viru County is described and data on the emission of pollutants in 1995-1998 are presented by industrial enterprises and by individual pollutants. A thorough analysis of the concentration of pollutants in the atmospheric air and air quality of towns and concrete air monitoring data are presented. Changes in the air quality are analysed by towns as well as by pollutants. An analysis of the dynamics of the changes in emissions and air quality showed that after a low concentration of pollutants in the atmospheric air in 1993-1995 a tendency towards worsening air quality occurred in 1995-1997. The concentration of some pollutants, for example phenol, has again reached the level of 1990-1991 when the largest amounts of pollutants were emitted into the air. These are signs of some new intensification of production activity in the region, but also of decreasing interest in environmental issues. Although according to reports the total volume of pollutants emitted into the atmosphere in Ida-Viru County has fallen nearly twice as compared with 1991, air monitoring data do not corroborate this. Hazardous pollution incidences may emerge at Saka and in the district of Jaerve in Kohtla-Jaerve in case of unfavourable weather conditions (no wind, high air temperature). The analysis of monitoring data revealed a necessity to improve the system of collecting and processing air monitoring data. For example, at present it is not possible to make a thorough analysis (including correlation analysis of the concentrations of pollutants and direction of winds) of the towns of Narva various objects on an undermine objective conclusions about the origin of pollutants cannot be drawn. It is necessary to guarantee that the existing automatic monitoring system OPSIS should be kept in working order as it is of great significance in monitoring and objective estimation of the air quality in Jaerve district in Kohtla-Jaerve. Presently OPSIS is

  6. Cooperative study with sup(99m)Tc diisopropil-IDA on biliary tract diseases

    International Nuclear Information System (INIS)

    Mitta, A.E.A.; Mollerach, F; Almeida, C.A.

    1982-01-01

    The results of a cooperative study on the investigation of the biliary tract with sup(99m)Tc diisopropyl-IDA are presented. 15 normal volunteers and 75 patients with acute cholecystitis (AC), chronic cholecystitis (CC), hepatocellular jaundice (HCJ), incomplete extrahepatic biliary obstruction (IEBO) and complete extrahepatic biliary obstruction (CEBO) were studied. The biological behaviour of the radiopharmaceutical in the two groups was determined through the measurement of the uptake times and of the times of arrival in the hepatic parenchyma, in the intra and extrahepatic bile ducts, in the gallbladder, in the duodenum and in the kidneys. The pathophysiologic features found in the AC, CC, HCJ, IEBO and CEBO are described. It is concluded that the procedure has a selective indication in the AC, that its value is limited in the CC, and that in jaundice, except in very special situations, the method gives very little information of clinic value. The possibility of performing cooperative scientific studies between Latin-American Departments, increasing their efficiency, is emphasized. (author) [es

  7. The IDA-80 measurement evaluation programme on mass spectrometric isotope dilution analysis of uranium and plutonium. Vol. 2

    International Nuclear Information System (INIS)

    Bievre, P. de; Gallet, M.; Hendrickx, F.; Lycke, E.; Wolters, W.H.; Mainka, E.; Wertenbach, H.

    1984-12-01

    A description is given of the test samples for the IDA-80 interlaboratory measurement evaluation programme. The preparation is described from the delivery of authentic reprocessing plant input samples (WAK Karlsruhe), their treatment at the IRCh-KfK and their further preparation and bottling at CBNM-Geel. All test samples have been characterized with best methods and instrumentation available at CBNM Geel and NBS Washington. Joint certified values for U/Pu element and isotopes content of a real-life and of a synthetic input test material were established, to serve the evaluation of participant's results. Full details of packaging, transport requirements and transport formalities in order to dispatch the samples world wide are also given. (orig.) [de

  8. Value of sup(99m)Tc-diethyl-IDA scintigraphy for the diagnosis of biliary atresia

    Energy Technology Data Exchange (ETDEWEB)

    Bourdelat, D.; Gruel, Y.; Guibert, L.; Babut, J.M. (Hopital Pontchaillou 35 - Rennes (France)); Bourguet, P.; Herry, J.Y. (Centre Eugene Marquis, CHR Pontchaillou, 35 - Rennes (France))

    1983-04-01

    With reference to three cases, the value of cholescintigraphy for the diagnosis of biliary atresia is underscored. With this procedure, surgical indications can be determined in neonates with jaundice persisting beyond the physiologic period. Clolescintigraphy can be repeated as it is easy to perform, safe and well tolerated. sup(99m)Tc-diethyl-IDA (technetium 99m labelled N-(2,6 diethyl-acetanilide)-iminodiacetic acid) scintigraphy was carried out in eight neonates. This procedure helped to outrule the diagnosis of biliary atresia in 5 cases (1 choledochal cyst, 1 alpha-1-antitrypsin deficiency and 3 neonatal hepatitis'). Scintigraphic images and time/activity curves generated simultaneously from equal surfaces over the heart and liver were analyzed separately. A good uptake by the liver (rapid decrease in the cardiac curve) with subsequent retention (no decrease in the hepatic curve) is suggestive of biliary atresia. No activity is detected in the biliary ducts or intestinal tract. Post-operatively, cholescintigraphy is a useful tool for controling the efficiency of the surgical procedure.

  9. La relación entre la antropología mexicana y ecuatoriana: ¿Un camino de ida y vuelta?

    Directory of Open Access Journals (Sweden)

    Fernando García

    2014-06-01

    Full Text Available Este trabajo consiste en una revisión del desarrollo de la antropología mexicana y ecuatoriana desde la perspectiva de los diálogos que atraviesan las propuestas teóricas y metodológicas, considerando desde la formación de profesionales hasta la puesta en marcha de políticas públicas relacionadas con la llamada “antropología aplicada”. Mediante un esbozo rápido y general de seis décadas del naciente pensamiento antropológico ecuatoriano –aunque sin que este sea un balance– se busca establecer cómo la interrelación entre antropología mexicana y ecuatoriana, muestra un camino de ida y vuelta, construido por el cruce de diversas perspectivas teóricas generadas al interior del debate disciplinar con los énfasis e intereses diferenciados de los actores locales.

  10. The Constraints of Literary Paradigms: Christian Mythology and the Jungle in Ida, a non-fiction picturebook on evolution by Jørn Hurum, Torstein Helleve and Esther van Hulsen

    OpenAIRE

    Ørjasæter, Kristin

    2015-01-01

    Ida (2011), written by Jørn Hurum and Torstein Helleve and illustrated by Esther van Hulsen, is a non-fiction picturebook for children with an ambitious objective. It presents a fossil, the findings from the study of this fossil, and the dispute over the validity of the results. The composition of the text is threefold: the book opens with an illustrative story about the life and death of the primate that ends up becoming the fossil in question, subsequently introduces a lexicographical secti...

  11. Análisis de materiales didácticos para enseñar Ciencias Sociales en Educación Primaria: “Un camino de ida y vuelta”

    OpenAIRE

    Mon Alday, Estefanía

    2013-01-01

    Con este Trabajo de Fin de Grado se pretende un acercamiento al tema del análisis de materiales didácticos para enseñar Ciencias Sociales en Educación Primaria y más concretamente se pretende analizar los materiales utilizados con el alumnado de 5º de primaria durante el desarrollo del Proyecto “Un Camino de Ida y Vuelta” en el Colegio Público de Educación Infantil y Primaria “Marqués de Santillana” en la localidad de Palencia. En la primera parte de este trabajo se realiza una revisión t...

  12. Application of Incremental Dynamic Analysis (IDA Method for Studying the Dynamic Behavior of Structures During Earthquakes

    Directory of Open Access Journals (Sweden)

    M. Javanpour

    2017-02-01

    Full Text Available Prediction of existing buildings’ vulnerability by future earthquakes is one of the most essential topics in structural engineering. Modeling steel structures is a giant step in determining the damage caused by the earthquake, as such structures are increasingly being used in constructions. Hence, two same-order steel structures with two types of structural systems were selected (coaxial moment frames and moment frame. In most cases, a specific structure needs to satisfy several functional levels. For this purpose, a method is required to determine the input request to the structures under possible earthquakes. Therefore, the Incremental Dynamic Analysis (IDA was preferred to the Push-Over non-linear static method for the analysis and design of the considered steel structures, due its accuracy and effect of higher modes at the same time intervals. OpenSees software was used to perform accurate nonlinear analysis of the steel structure. Two parameters (spectral acceleration and maximum ground acceleration were introduced to the modeled frames to compare the numerical correlations of seismic vulnerability obtained by two statistical methods based on the "log-normal distribution" and "logistics distribution", and finally, the parameters of displacement and drift were assessed after analysis.

  13. Measurement of isotope abundance variations in nature by gravimetric spiking isotope dilution analysis (GS-IDA).

    Science.gov (United States)

    Chew, Gina; Walczyk, Thomas

    2013-04-02

    Subtle variations in the isotopic composition of elements carry unique information about physical and chemical processes in nature and are now exploited widely in diverse areas of research. Reliable measurement of natural isotope abundance variations is among the biggest challenges in inorganic mass spectrometry as they are highly sensitive to methodological bias. For decades, double spiking of the sample with a mix of two stable isotopes has been considered the reference technique for measuring such variations both by multicollector-inductively coupled plasma mass spectrometry (MC-ICPMS) and multicollector-thermal ionization mass spectrometry (MC-TIMS). However, this technique can only be applied to elements having at least four stable isotopes. Here we present a novel approach that requires measurement of three isotope signals only and which is more robust than the conventional double spiking technique. This became possible by gravimetric mixing of the sample with an isotopic spike in different proportions and by applying principles of isotope dilution for data analysis (GS-IDA). The potential and principle use of the technique is demonstrated for Mg in human urine using MC-TIMS for isotopic analysis. Mg is an element inaccessible to double spiking methods as it consists of three stable isotopes only and shows great potential for metabolically induced isotope effects waiting to be explored.

  14. Hemorroidectomia híbrida: uma nova abordagem no tratamento das hemorróidas mistas Hybrid hemorrhoidectomy: a new approach in the treatment of hemorrhoids

    Directory of Open Access Journals (Sweden)

    Haroldo Alfredo Santos

    2006-12-01

    Full Text Available Este trabalho tem por objetivo apresentar uma nova abordagem mini-invasiva das Hemorróidas Mistas, a Hemorroidectomia Híbrida, que consiste na associação da Ligadura Elástica (LE das Hemorróidas Internas com a ressecção complementar dos Plicomas Externos sob anestesia local. Num universo de 326 cirurgias orificiais realizadas na Proctoclínica num período de 4 anos, 300 (92% foram submetidos a procedimentos mini-invasivos, 223 (68,40% foram submetidos a LE como tratamento exclusivo e 77 (23,60% à Hemoirroidectomia Híbrida e 26 (8% foram submetidos a outros procedimentos cirúrgicos (Hemorroidectomias a Milligan-Morgan, Fistulectomias etc. A abordagem proposta permite absenteísmo mínimo ao trabalho, mini-invasividade e baixa morbidade pós-operatória, ressaltando-se ainda a realização ambulatorial, excelente tolerabilidade e baixos custos.The goal of this work is to present a new mini-invasive approach of the Internal and External Hemorrhoids Treatment, the Hybrid Hemorrhoidectomy, that consists of an association of the Rubber Band Ligation (RBL of the Internal Hemorrhoids with complementary withdraw of the External Piles under local anesthesia. In a universe of 326 anal surgeries carried through in Proctoclínica in a period of 4 years, a number of 300 patients (92% had been submitted to mini-invasive procedures (223 (68,40% had been submitted to RBL as exclusive treatment and 77 (23,60% to Hybrid Hemorrhoidectomy and 26 patients (8% had been submitted to other surgical procedures (Hemorrhoidectomy Milligan-Morgan, Fistulectomy, etc. The proposal approach allows minimum absenteism to the work, mini-invasivity and low pos-operative morbidity with the advantage of office and outpatient procedures, excellent tolerability and low costs.

  15. Prospective evaluation of /sup 99m/Tc-IDA cholescintigraphy and gray-scale ultrasound in the diagnosis of acute cholecystitis

    International Nuclear Information System (INIS)

    Ralls, P.W.; Colletti, P.M.; Halls, J.M.; Siemsen, J.K.

    1982-01-01

    Prospective analysis of the efficacy of /sup 99m/Tc-IDA cholescintigraphy and cholecystosonography showed that both are excellent techniques for assessing patients with suspected acute cholecystitis (accuracy 84.7% and 88.1% respectively). Consequently, the choice of tests selected to evaluate patients with suspected acute cholecystitis depends on several factors including; (a.) quality of equipment available; (b.) capability of the technologist performing the examination; (c.) relative experience of the physician supervising the examination; and (d.) willingness of the surgical consultant to accept a positive examination as sufficient evidence to perform emergency surgery. The authors feel that cholecystosonography should be used to assess the presence of acute cholecystitis in jaundiced patients because of its capability in the assessment of bile duct dilatation, and because of the lower reliability of cholescintigraphy when bile duct obstruction is possible (i.e., in jaundice). Ancillary findings in cholecystosonography and cholescintigraphy can aid in the differential diagnosis of acute right upper quandrant pain syndromes

  16. Prospective evaluation of 99/sup m/Tc-IDA cholescintigraphy and Gray-scale ultrasound in the diagnosis of acute cholecystitis

    International Nuclear Information System (INIS)

    Ralls, P.W.; Colletti, P.M.; Halls, J.M.; Siemsen, J.K.

    1982-01-01

    Prospective analysis of the efficacy of 99 /sup m/Tc-IDA cholescintigraphy and cholecystosonography showed that both are excellent techniques for assessing patients with suspected acute cholecystitis (accuracy 84.7% and 88.1% respectively). Consequently, the choice of tests selected to evaluate patients with suspected acute cholecystitis depends on several factors, including; (a.) quality of equipment available; (b.) capability of the technologist performing the examination; (c.) relative experience of the physician supervising the examination; and (d.) willingness of the surgical consultant to accept a positive examination as sufficient evidence to perform emergency surgery. The authors feel that cholecystosonography should be used to asses the presence of acute cholecystitis in jaundiced patients because of its capability in the assessment of bile duct dilation, and because of the lower reliability of cholescintigraphy when bile duct obstruction is possible (i.e., in jaundice). Ancillary findings in cholecystosonography and cholescintigraphy can aid in the differential diagnosis of acute right upper quadrant pain syndromes

  17. A methodology for collection and analysis of human error data based on a cognitive model: IDA

    International Nuclear Information System (INIS)

    Shen, S.-H.; Smidts, C.; Mosleh, A.

    1997-01-01

    This paper presents a model-based human error taxonomy and data collection. The underlying model, IDA (described in two companion papers), is a cognitive model of behavior developed for analysis of the actions of nuclear power plant operating crew during abnormal situations. The taxonomy is established with reference to three external reference points (i.e. plant status, procedures, and crew) and four reference points internal to the model (i.e. information collected, diagnosis, decision, action). The taxonomy helps the analyst: (1) recognize errors as such; (2) categorize the error in terms of generic characteristics such as 'error in selection of problem solving strategies' and (3) identify the root causes of the error. The data collection methodology is summarized in post event operator interview and analysis summary forms. The root cause analysis methodology is illustrated using a subset of an actual event. Statistics, which extract generic characteristics of error prone behaviors and error prone situations are presented. Finally, applications of the human error data collection are reviewed. A primary benefit of this methodology is to define better symptom-based and other auxiliary procedures with associated training to minimize or preclude certain human errors. It also helps in design of control rooms, and in assessment of human error probabilities in the probabilistic risk assessment framework. (orig.)

  18. Morphological and functional criteria of hepatobiliary scintigraphy with IDA derivatives in patients with hepatocellular jaundice

    International Nuclear Information System (INIS)

    Biersack, H.J.; Breuel, H.P.; Altland, H.; Bell, E.

    1979-01-01

    In 31 Patients with histologically proven hepatocellular jaundice hepatobiliary scintigraphy with Tc-99m labelled IDA derivatives was performed. Results were classified under morphological (demonstration of liver parenchyma, ductus choledochus, bile ducts, gallbladder, kidney) and functional (Tsub(max), halftime of bile excretion, appearance of activity in ductus choledochus, gallbladder, and intestines) criteria. The liver parenchyma could be demonstrated in 90.3% of cases, ductus choledochus in 71% and the gallbladder in 72.4%. The type of tracer excretion into the intestines showed 9.5% activity accumulation in the gallbladder with late bile excretion into the intestines and 90.5% early activity excretion into the duodenum with late filling of the gallbladder. The intrahepatic bile ducts were demonstrated in 22.6% (left hepatic duct) and 6.5% (right hepatic duct). In 35.5% of cases the kidneys were still visible after 15 min p.i. All cases showed - sometimes delayed - bile excretion into the GI tract. The time of appearance of activity in ductus choledochus (18.4 min) and gallbladder (39.5 min) was delayed. The liver histogram showed likewise delayed values concerning Tsub(max) (14.3 min) and half life of tracer excretion (> 30 min) when compared to controls. The differentiation of hepatocellular jaundice from obstructive jaundice is possible by the demonstration of bile excretion into the intestines, normal width of the bile ducts, and filling of the gallbladder. (orig.) [de

  19. The IDA-80 measurement evaluation programme on mass spectrometric isotope dilution analysis of uranium and plutonium. Vol. 1

    International Nuclear Information System (INIS)

    Beyrich, W.; Golly, W.; Spannagel, G.; Kernforschungszentrum Karlsruhe G.m.b.H.; Bievre, P. de; Wolters, W.

    1984-12-01

    The main objective was the acquisition of basic data on the uncertainties involved in the mass spectrometric isotope dilution analysis as applied to the determination of uranium and plutonium in active feed solutions of reprocessing plants. The element concentrations and isotopic compositions of all test materials used were determined by CBNM and NBS with high accuracy. The more than 60000 analytical data reported by the participating laboratories were evaluated by statistical methods applied mainly to the calculation of estimates of the variances for the different uncertainty components contributing to the total uncertainty of this analytical technique. Attention was given to such topics as sample ageing, influence of fission products, spike calibration, ion fractionation, Pu-241 decay correction, minor isotope measurement and errors in data transfer. Furthermore, the performance of the 'dried sample' technique and the 'in-situ' spiking method of undiluted samples of reprocessing fuel solution with U-235/Pu-242 metal alloy spikes, were tested successfully. Considerable improvement of isotope dilution analysis in this safeguards relevant application during the last decade is shown as compared to the results obtained in the IDA-72 interlaboratory experiment, organized by KfK in 1972 on the same subject. (orig./HP) [de

  20. Rethinking the origins of autism: Ida Frye and the unraveling of children's inner world in the Netherlands in the late 1930s.

    Science.gov (United States)

    Van Drenth, Annemieke

    2018-01-01

    Historiographies on the phenomenon of "autism" display Leo Kanner and Hans Asperger as the great pioneers. The recent controversy on who was first in "discovering" autism urges research into the question of how scientific discoveries relate to processes of academic reflection and social intervention. The Netherlands provide an interesting case in pioneering work in autism, since Dutch experts described autism in children already in the late 1930s, preceding the first publications on autism in children by Kanner and Asperger. This paper examines the Dutch origins of autism by focusing on Ida Frye's contribution to the teamwork at the Paedological Institute in Nijmegen, which resulted in descriptions of children with autism. The theoretical aim of this paper is to underline the importance of the productive interplay between social interventions and scientific efforts concerning the complex inner world of special children. © 2017 Wiley Periodicals, Inc.

  1. The hydrocarbon-degrading marine bacterium Cobetia sp. strain MM1IDA2H-1 produces a biosurfactant that interferes with quorum sensing of fish pathogens by signal hijacking

    Science.gov (United States)

    Ibacache-Quiroga, C; Ojeda, J; Espinoza-Vergara, G; Olivero, P; Cuellar, M; Dinamarca, M A

    2013-01-01

    Summary Biosurfactants are produced by hydrocarbon-degrading marine bacteria in response to the presence of water-insoluble hydrocarbons. This is believed to facilitate the uptake of hydrocarbons by bacteria. However, these diffusible amphiphilic surface-active molecules are involved in several other biological functions such as microbial competition and intra-or inter-species communication. We report the isolation and characterization of a marine bacterial strain identified as Cobetia sp. MM1IDA2H-1, which can grow using the sulfur-containing heterocyclic aromatic hydrocarbon dibenzothiophene (DBT). As with DBT, when the isolated strain is grown in the presence of a microbial competitor, it produces a biosurfactant. Because the obtained biosurfactant was formed by hydroxy fatty acids and extracellular lipidic structures were observed during bacterial growth, we investigated whether the biosurfactant at its critical micelle concentration can interfere with bacterial communication systems such as quorum sensing. We focused on Aeromonas salmonicida subsp. salmonicida, a fish pathogen whose virulence relies on quorum sensing signals. Using biosensors for quorum sensing based on Chromobacterium violaceum and Vibrio anguillarum, we showed that when the purified biosurfactant was mixed with N-acyl homoserine lactones produced by A. salmonicida, quorum sensing was inhibited, although bacterial growth was not affected. In addition, the transcriptional activities of A. salmonicida virulence genes that are controlled by quorum sensing were repressed by both the purified biosurfactant and the growth in the presence of Cobetia sp. MM1IDA2H-1. We propose that the biosurfactant, or the lipid structures interact with the N-acyl homoserine lactones, inhibiting their function. This could be used as a strategy to interfere with the quorum sensing systems of bacterial fish pathogens, which represents an attractive alternative to classical antimicrobial therapies in fish

  2. The IDA-LIKE peptides IDL6 and IDL7 are negative modulators of stress responses in Arabidopsis thaliana.

    Science.gov (United States)

    Vie, Ane Kjersti; Najafi, Javad; Winge, Per; Cattan, Ester; Wrzaczek, Michael; Kangasjärvi, Jaakko; Miller, Gad; Brembu, Tore; Bones, Atle M

    2017-06-15

    Small signalling peptides have emerged as important cell to cell messengers in plant development and stress responses. However, only a few of the predicted peptides have been functionally characterized. Here, we present functional characterization of two members of the IDA-LIKE (IDL) peptide family in Arabidopsis thaliana, IDL6 and IDL7. Localization studies suggest that the peptides require a signal peptide and C-terminal processing to be correctly transported out of the cell. Both IDL6 and IDL7 appear to be unstable transcripts under post-transcriptional regulation. Treatment of plants with synthetic IDL6 and IDL7 peptides resulted in down-regulation of a broad range of stress-responsive genes, including early stress-responsive transcripts, dominated by a large group of ZINC FINGER PROTEIN (ZFP) genes, WRKY genes, and genes encoding calcium-dependent proteins. IDL7 expression was rapidly induced by hydrogen peroxide, and idl7 and idl6 idl7 double mutants displayed reduced cell death upon exposure to extracellular reactive oxygen species (ROS). Co-treatment of the bacterial elicitor flg22 with IDL7 peptide attenuated the rapid ROS burst induced by treatment with flg22 alone. Taken together, our results suggest that IDL7, and possibly IDL6, act as negative modulators of stress-induced ROS signalling in Arabidopsis. © The Author 2017. Published by Oxford University Press on behalf of the Society for Experimental Biology.

  3. Coastal Storm Surge Analysis: Modeling System Validation. Report 4: Intermediate Submission No. 2.0

    Science.gov (United States)

    2013-07-01

    Hurricane Isabel, Hurricane Ernesto, and Extratropical Storm Ida. Model skill was accessed by quantitative comparison of model output to wind, wave...25. Extratropical Storm Nor’Ida maximum wind speeds. ......................................................... 41  Figure 26. Extratropical Storm ...Nor’Ida wind validation stations. ........................................................ 42  Figure 27. Comparisons of Extratropical Storm Nor’Ida wind

  4. Iron deficiency anemia and cognitive function in infancy.

    Science.gov (United States)

    Carter, R Colin; Jacobson, Joseph L; Burden, Matthew J; Armony-Sivan, Rinat; Dodge, Neil C; Angelilli, Mary Lu; Lozoff, Betsy; Jacobson, Sandra W

    2010-08-01

    This study examined effects of iron deficiency anemia (IDA) on specific domains of infant cognitive function and the role of IDA-related socioemotional deficits in mediating and/or moderating these effects. Infants were recruited during routine 9-month visits to an inner-city clinic. IDA was defined as hemoglobin level or =2 abnormal iron deficiency indicators (mean corpuscular volume, red cell distribution width, zinc protoporphyrin, transferrin saturation, and ferritin). At 9 and 12 months, the Fagan Test of Infant Intelligence (FTII); A-not-B task; Emotionality, Activity, and Sociability Temperament Survey; and Behavior Rating Scale were administered. Analyses were adjusted for potential confounders, including age and sociodemographic variables. Twenty-eight infants met criteria for IDA, 28 had nonanemic iron deficiency (NA ID) and 21 had iron sufficiency (IS). There was a linear effect for object permanence at 9 months: infants with IDA were least likely to exhibit object permanence, IS most likely, and NA ID intermediate. Infants with IDA and those with hemoglobin level object permanence and short-term memory encoding and/or retrieval in infants with IDA at 9 months. These cognitive effects were attributable, in part, to IDA-related deficits in socioemotional function. Children with poor socioemotional performance seem to be more vulnerable to the effects of IDA on cognitive function.

  5. "Gorjatshaja desjatka" industrianogo regiona / Jevgeni Ashihmin

    Index Scriptorium Estoniae

    Ashihmin, Jevgeni

    2005-01-01

    Narva-Jõesuus toimunud ajalehe Äripäev Ida-Virumaa arengukonverentsil anti üle auhinnad edukamatele Ida-Virumaa ettevõtetele. Ajakirja Äripäev Ida-Virumaa TOP-i esikolmikusse kuuluvad Kohtla-Järve ettevõtted AS Nitrofert ja AS Viru Keemia Grupp ning Jõhvis asuv OÜ T.R.Tamme Auto. Ülevaade konverentsist ja Ida-Virumaa maavanema Ago Silde esinemisest

  6. Chemins de fer en mutation dans l'Europe médiane / Antoine Kunth

    Index Scriptorium Estoniae

    Kunth, Antoine

    2002-01-01

    Kesk- ja Ida-Euroopa raudteestruktuuride arengust sotsialismiperioodist tänapäevani. Reformid ja erastamine. Kesk- ja Ida-Euroopa riikide vahelistest raudteeliinidest. Tabelid. Joonis: Kümme Kesk- ja Ida-Euroopa transpordikoridori.

  7. EAARL Coastal Topography-Fire Island National Seashore, New York, Post-Nor'Ida, 2009

    Science.gov (United States)

    Nayegandhi, Amar; Vivekanandan, Saisudha; Brock, J.C.; Wright, C.W.; Nagle, D.B.; Bonisteel-Cormier, J.M.; Fredericks, Xan; Stevens, Sara

    2010-01-01

    These remotely sensed, geographically referenced elevation measurements of lidar-derived bare-earth (BE) and first-surface (FS) topography datasets were produced collaboratively by the U.S. Geological Survey (USGS), St. Petersburg Coastal and Marine Science Center, St. Petersburg, FL, and the National Park Service (NPS), Northeast Coastal and Barrier Network, Kingston, RI. This project provides highly detailed and accurate datasets of a portion of the Fire Island National Seashore in New York, acquired post-Nor'Ida (November 2009 nor'easter) on December 4, 2009. The datasets are made available for use as a management tool to research scientists and natural-resource managers. An innovative airborne lidar instrument originally developed at the NASA Wallops Flight Facility, and known as the Experimental Advanced Airborne Research Lidar (EAARL), was used during data acquisition. The EAARL system is a raster-scanning, waveform-resolving, green-wavelength (532-nanometer) lidar designed to map near-shore bathymetry, topography, and vegetation structure simultaneously. The EAARL sensor suite includes the raster-scanning, water-penetrating full-waveform adaptive lidar, a down-looking red-green-blue (RGB) digital camera, a high-resolution multispectral color-infrared (CIR) camera, two precision dual-frequency kinematic carrier-phase GPS receivers, and an integrated miniature digital inertial measurement unit, which provide for sub-meter georeferencing of each laser sample. The nominal EAARL platform is a twin-engine aircraft, but the instrument was deployed on a Pilatus PC-6. A single pilot, a lidar operator, and a data analyst constitute the crew for most survey operations. This sensor has the potential to make significant contributions in measuring sub-aerial and submarine coastal topography within cross-environmental surveys. Elevation measurements were collected over the survey area using the EAARL system, and the resulting data were then processed using the Airborne

  8. Strategy for the investigation of hazardous substances in industrial effluents: IDA (Industrial Discharge Assessment)

    Energy Technology Data Exchange (ETDEWEB)

    Reemtsma, T.; Klinkow, N.

    2001-08-01

    The assessment of amounts and effects of hazardous substances in industrial effluents necessitates a combination of chemical and biological investigations. Therefore in this study a strategy for the investigation of hazardous substances in wastewater discharges was developed which connects the parameters persistence, bioaccumulation, and aquatic toxicity. The strategy IDA (Industrial Discharge Assessment) was elaborated based on the evaluation of existing investigation strategies and the available test systems. The strategy has a modular structure to assure a flexible investigation with regard to the particularities of a given wastewater. After the determination of acute and chronic toxicity and genotoxicity a microbial degradation test is carried out to obtain the persistent wastewater fraction. The bioaccumulating substances are determined from this fraction by solid-phase extraction. Within the strategy differences between direct and indirect discharges are taken into account and particulate matter is considered as well. By the modular linking it can be determined if a wastewater contains toxic and persistent and bioaccumulating substances, which present an important potential of hazard for the aquatic environment. The first application of the strategy on three wastewater samples of the chemical and the metal processing industry showed that the strategy can be used as planned. (orig.) [German] Die Erfassung der Gehalte und Wirkungen gefaehrlicher Stoffe in Abwassereinleitungen der Industrie erfordert eine Kombination chemischer und biologischer Untersuchungen, die ueber das bisher in der AbwV festgelegte Mass hinausgeht. In dieser Studie wurde deshalb eine Untersuchungsstrategie fuer gefaehrliche Stoffe in Abwasserleitungen entwickelt, die die Parameter Persistenz, Bioakkumulierbarkeit und Toxizitaet auch experimentell verknuepft. Die Ausarbeitung erfolgte nach Auswertung der international bestehenden Untersuchungsstrategien sowie der zur Verfuegung stehenden

  9. Invariant density analysis: modeling and analysis of the postural control system using Markov chains.

    Science.gov (United States)

    Hur, Pilwon; Shorter, K Alex; Mehta, Prashant G; Hsiao-Wecksler, Elizabeth T

    2012-04-01

    In this paper, a novel analysis technique, invariant density analysis (IDA), is introduced. IDA quantifies steady-state behavior of the postural control system using center of pressure (COP) data collected during quiet standing. IDA relies on the analysis of a reduced-order finite Markov model to characterize stochastic behavior observed during postural sway. Five IDA parameters characterize the model and offer physiological insight into the long-term dynamical behavior of the postural control system. Two studies were performed to demonstrate the efficacy of IDA. Study 1 showed that multiple short trials can be concatenated to create a dataset suitable for IDA. Study 2 demonstrated that IDA was effective at distinguishing age-related differences in postural control behavior between young, middle-aged, and older adults. These results suggest that the postural control system of young adults converges more quickly to their steady-state behavior while maintaining COP nearer an overall centroid than either the middle-aged or older adults. Additionally, larger entropy values for older adults indicate that their COP follows a more stochastic path, while smaller entropy values for young adults indicate a more deterministic path. These results illustrate the potential of IDA as a quantitative tool for the assessment of the quiet-standing postural control system.

  10. Current opinion on the management of iron deficiency anaemia in gastrointestinal diseases.

    Science.gov (United States)

    Derovs, Aleksejs; Pokrotnieks, Juris; Derova, Jelena; Danilans, Anatolijs; Pukitis, Aldis; Dombure, Polina; Leiniece, Sandra; Zeltina Indra

    2014-01-01

    Iron deficiency is the most common cause of anaemia in the world. Despite frequently weak and masked clinical presentation of iron deficiency anaemia (IDA), this disease is very serious with complications leading to early mortality. In the developed countries IDA is predominantly diagnosed as the complication of another disease or as the result of major bleeding events. Diagnosis of IDA should be based on laboratory findings i.e. haemoglobin, mean corpuscular hemoglobin concentration and ferritin. Latter is the most sensitive marker for iron deficiency. Anaemia of chronic disease should be taken into an account as a potential differential diagnosis or coexisting state. For women in fertility age with IDA, gynaecological disorders should be ruled out first. Males and postmenopausal women with IDA should undergo upper, lower and in certain cases capsule endoscopy and/or enteroscopy to find a plausible cause of IDA. The ultimate goal of therapy is to find out and treat the primary cause of IDA. Iron body stores should be restored using either oral or parenteral iron preparations. The use of parenteral iron preparations in patients with gastrointestinal pathologies is often clinically substantiated for the treatment of IDA. Red blood cell transfusion should be administered in emergency cases only.

  11. Chelating capture and magnetic removal of non-magnetic heavy metal substances from soil

    Science.gov (United States)

    Fan, Liren; Song, Jiqing; Bai, Wenbo; Wang, Shengping; Zeng, Ming; Li, Xiaoming; Zhou, Yang; Li, Haifeng; Lu, Haiwei

    2016-02-01

    A soil remediation method based on magnetic beneficiation is reported. A new magnetic solid chelator powder, FS@IDA (core-shell Fe3O4@SiO2 nanoparticles coated with iminodiacetic acid chelators), was used as a reactive magnetic carrier to selectively capture non-magnetic heavy metals in soil by chelation and removal by magnetic separation. FS@IDA was prepared via inorganic-organic and organic synthesis reactions that generated chelating groups on the surface of magnetic, multi-core, core-shell Fe3O4@SiO2 (FS) nanoparticles. These reactions used a silane coupling agent and sodium chloroacetate. The results show that FS@IDA could chelate the heavy metal component of Cd, Zn, Pb, Cu and Ni carbonates, lead sulfate and lead chloride in water-insoluble salt systems. The resulting FS@IDA-Cd and FS@IDA-Pb chelates could be magnetically separated, resulting in removal rates of approximately 84.9% and 72.2% for Cd and Pb, respectively. FS@IDA could not remove the residual heavy metals and those bound to organic matter in the soil. FS@IDA did not significantly alter the chemical composition of the soil, and it allowed for fast chelating capture, simple magnetic separation and facilitated heavy metal elution. FS@IDA could also be easily prepared and reprocessed.

  12. Tc-99m-BrIDA hepatobiliary (HIDA) scan has a low sensitivity for detecting biliary complications after orthotopic liver transplantation in patients with hyperbilirubinemia

    International Nuclear Information System (INIS)

    Hopkins, L.O.; Feyssa, E.; Parsikia, A.; Khanmoradi, K.; Zaki, R.; Campos, S.; Araya, V.; Tran, H.; Ortiz, J.

    2011-01-01

    Tc-99m-BrIDA hepatobiliary scans are noninvasive tests for detecting biliary leaks and obstructions. However, there is low sensitivity and specificity in patients with hyperbilirubinemia. Biliary complications (BC) are the Achilles heel of orthotopic liver transplantation (OLT). We questioned whether hyperbilirubinemia in liver transplant recipients rendered HIDA scanning less dependable. HIDA findings were compared to endoscopic retrograde cholangiopancreatography, laparotomy, and clinical course. Results were categorized as follows: true positive (TP), true negative (TN), false positive (FP), false negative (FN), or nondiagnostic/inconclusive. We searched for variables associated with erroneous or nondiagnostic tests which we defined as all examinations determined to be FP, FN and/or nondiagnostic/inconclusive. Thirty-four patients underwent a HIDA scan. The sensitivity and specificity were 70 and 100%. The sensitivity of HIDA improved to 100% in patients with a total bilirubin (TB) 5 mg/dl. One FN had a TB <5 mg/dl, but was determined inconclusive due to the roux-en-Y. HIDA scans performed when the total bilirubin was <5 mg/dl had a high sensitivity and specificity for detecting biliary complications after OLT. However, when the total bilirubin exceeded 5 mg/dl, the specificity was still 100% but the numbers of nondiagnostic/inconclusive and FN exams were increased. (author)

  13. Gclust Server: 97794 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 97794 CEL_B0244.2_25143920 Cluster Sequences Related Sequences(171) 767 ida-1: related to Islet cell Diabete...ida-1: related to Islet cell Diabetes Autoantigen family member (ida-1) Number of Sequences 1 Homologs 1 Clu

  14. Social Costs of Iron Deficiency Anemia in 6–59-Month-Old Children in India

    Science.gov (United States)

    Plessow, Rafael; Arora, Narendra Kumar; Brunner, Beatrice; Tzogiou, Christina; Eichler, Klaus; Brügger, Urs; Wieser, Simon

    2015-01-01

    Introduction Inadequate nutrition has a severe impact on health in India. According to the WHO, iron deficiency is the single most important nutritional risk factor in India, accounting for more than 3% of all disability-adjusted life years (DALYs) lost. We estimate the social costs of iron deficiency anemia (IDA) in 6–59-month-old children in India in terms of intangible costs and production losses. Materials and Methods We build a health economic model estimating the life-time costs of a birth cohort suffering from IDA between the ages of 6 and 59 months. The model is stratified by 2 age groups (6–23 and 24–59-months), 2 geographical areas (urban and rural), 10 socio-economic strata and 3 degrees of severity of IDA (mild, moderate and severe). Prevalence of anemia is calculated with the last available National Family Health Survey. Information on the health consequences of IDA is extracted from the literature. Results IDA prevalence is 49.5% in 6–23-month-old and 39.9% in 24–58-month-old children. Children living in poor households in rural areas are particularly affected but prevalence is high even in wealthy urban households. The estimated yearly costs of IDA in 6–59-month-old children amount to intangible costs of 8.3 m DALYs and production losses of 24,001 m USD, equal to 1.3% of gross domestic product. Previous calculations have considerably underestimated the intangible costs of IDA as the improved WHO methodology leads to a threefold increase of DALYs due to IDA. Conclusion Despite years of iron supplementation programs and substantial economic growth, IDA remains a crucial public health issue in India and an obstacle to the economic advancement of the poor. Young children are especially vulnerable due to the irreversible effects of IDA on cognitive development. Our research may contribute to the design of new effective interventions aiming to reduce IDA in early childhood. PMID:26313356

  15. Social Costs of Iron Deficiency Anemia in 6-59-Month-Old Children in India.

    Science.gov (United States)

    Plessow, Rafael; Arora, Narendra Kumar; Brunner, Beatrice; Tzogiou, Christina; Eichler, Klaus; Brügger, Urs; Wieser, Simon

    2015-01-01

    Inadequate nutrition has a severe impact on health in India. According to the WHO, iron deficiency is the single most important nutritional risk factor in India, accounting for more than 3% of all disability-adjusted life years (DALYs) lost. We estimate the social costs of iron deficiency anemia (IDA) in 6-59-month-old children in India in terms of intangible costs and production losses. We build a health economic model estimating the life-time costs of a birth cohort suffering from IDA between the ages of 6 and 59 months. The model is stratified by 2 age groups (6-23 and 24-59-months), 2 geographical areas (urban and rural), 10 socio-economic strata and 3 degrees of severity of IDA (mild, moderate and severe). Prevalence of anemia is calculated with the last available National Family Health Survey. Information on the health consequences of IDA is extracted from the literature. IDA prevalence is 49.5% in 6-23-month-old and 39.9% in 24-58-month-old children. Children living in poor households in rural areas are particularly affected but prevalence is high even in wealthy urban households. The estimated yearly costs of IDA in 6-59-month-old children amount to intangible costs of 8.3 m DALYs and production losses of 24,001 m USD, equal to 1.3% of gross domestic product. Previous calculations have considerably underestimated the intangible costs of IDA as the improved WHO methodology leads to a threefold increase of DALYs due to IDA. Despite years of iron supplementation programs and substantial economic growth, IDA remains a crucial public health issue in India and an obstacle to the economic advancement of the poor. Young children are especially vulnerable due to the irreversible effects of IDA on cognitive development. Our research may contribute to the design of new effective interventions aiming to reduce IDA in early childhood.

  16. Social Costs of Iron Deficiency Anemia in 6-59-Month-Old Children in India.

    Directory of Open Access Journals (Sweden)

    Rafael Plessow

    Full Text Available Inadequate nutrition has a severe impact on health in India. According to the WHO, iron deficiency is the single most important nutritional risk factor in India, accounting for more than 3% of all disability-adjusted life years (DALYs lost. We estimate the social costs of iron deficiency anemia (IDA in 6-59-month-old children in India in terms of intangible costs and production losses.We build a health economic model estimating the life-time costs of a birth cohort suffering from IDA between the ages of 6 and 59 months. The model is stratified by 2 age groups (6-23 and 24-59-months, 2 geographical areas (urban and rural, 10 socio-economic strata and 3 degrees of severity of IDA (mild, moderate and severe. Prevalence of anemia is calculated with the last available National Family Health Survey. Information on the health consequences of IDA is extracted from the literature.IDA prevalence is 49.5% in 6-23-month-old and 39.9% in 24-58-month-old children. Children living in poor households in rural areas are particularly affected but prevalence is high even in wealthy urban households. The estimated yearly costs of IDA in 6-59-month-old children amount to intangible costs of 8.3 m DALYs and production losses of 24,001 m USD, equal to 1.3% of gross domestic product. Previous calculations have considerably underestimated the intangible costs of IDA as the improved WHO methodology leads to a threefold increase of DALYs due to IDA.Despite years of iron supplementation programs and substantial economic growth, IDA remains a crucial public health issue in India and an obstacle to the economic advancement of the poor. Young children are especially vulnerable due to the irreversible effects of IDA on cognitive development. Our research may contribute to the design of new effective interventions aiming to reduce IDA in early childhood.

  17. Serum hepcidin-25 may replace the ferritin index in the Thomas plot in assessing iron status in anemic patients.

    Science.gov (United States)

    Thomas, C; Kobold, U; Balan, S; Roeddiger, R; Thomas, L

    2011-04-01

    Biochemical markers of iron deficiency do not distinguish iron-deficient anemia (IDA) from the anemia of chronic disease (ACD) and the combined state of ACD/IDA. Serum hepcidin-25 might be a marker resolving this problem. We investigated the extent to which serum hepcidin-25 enables the differentiation of the states above in comparison with the ferritin index plot, the so-called Thomas plot [soluble transferrin receptor (sTfR)/log ferritin and the reticulocyte hemoglobin content (CHr)]. Serum hepcidin-25 was determined in 155 anemic patients who were classified as having latent iron deficiency (latent ID), IDA, ACD, or ACD/IDA using the ferritin index plot (Thomas plot). Hepcidin-25 was determined using an isotope-dilution micro-HPLC-tandem mass spectrometry method. The ability to discriminate among these states based on serum hepcidin-25 alone or in combination with the CHr was evaluated in a receiver operating characteristic curve analysis and a comparison with the recently established ferritin index plot. Serum hepcidin-25 correlated with ferritin and the ferritin index. Use of a hepcidin-25 cutoff level of ≤4 nmol/l allowed the differentiation of IDA from ACD and ACD/IDA. Furthermore, the discrimination of ACD/IDA from ACD required combination with CHr in a new plot (hepcidin-25 and the CHr). The hepcidin-25 plot and the ferritin index plot showed a good correspondence in the differentiation of iron states in patients with anemia. Patients with IDA can be differentiated from ACD and ACD/IDA but not ACD from ACD/IDA based on hepcidin-25 alone. The combination of hepcidin-25 with CHr in the hepcidin-25 plot was useful for the differentiation of the states above. © 2010 Blackwell Publishing Ltd.

  18. Assessment of the use of LED phototherapy on bone defects grafted with hydroxyapatite on rats with iron-deficiency anemia and nonanemic: a Raman spectroscopy analysis.

    Science.gov (United States)

    de Castro, Isabele Cardoso Vieira; Rosa, Cristiane Becher; Dos Reis Júnior, João Alves; Moreira, Luiz Gaudêncio Passos; Aragão, Juliana S; Barbosa, Artur Felipe dos Santos; Silveira, Landulfo; Pinheiro, Antonio L B

    2014-09-01

    This study aimed to assess bone repair in defects grafted or not with hydroxyapatite (HA) on healthy and iron-deficiency anemia (IDA) rats submitted or not to LED phototherapy (LED-PT) by Raman spectroscopy. The animals were divided in eight groups with five rats each: Clot; Clot + LED; IDA + Clot; IDA + LED; Graft; Graft + LED; IDA + Graft; and IDA + Graft + LED. When appropriated, irradiation with IR LED (λ850 ± 10 nm, 150 mW, CW, Φ = 0.5 cm(2), 16 J/cm(2), 15 days) was carried out. Raman shifts: ∼ 960 [symmetric PO4 stretching (phosphate apatite)], ∼ 1,070 [symmetric CO3 stretching (B-type carbonate apatite)], and ∼ 1,454 cm(-1) [CH2/CH3 bending in organics (protein)] were analyzed. The mean peak values for ∼ 960, ∼ 1,070, and ∼ 1,454 cm(-1) were nonsignificantly different on healthy or anemic rats. The group IDA + Graft + LED showed the lowest mean values for the peak ∼ 960 cm(-1) when compared with the irradiated IDA group or not (p ≤ 0.001; p ≤ 0.001). The association of LED-PT and HA-graft showed lowest mean peak at ∼ 1,454 cm(-1) for the IDA rats. The results of this study indicated higher HA peaks as well as a decrease in the level of organic components on healthy animals when graft and LED phototherapy are associated. In the other hand, IDA condition interfered in the graft incorporation to the bone as LED phototherapy only improved bone repair when graft was not used.

  19. Promoting self-determination and financial security through innovative asset building approaches.

    Science.gov (United States)

    Burke-Miller, Jane K; Swarbrick, Margaret A; Carter, Tina M; Jonikas, Jessica A; Zipple, Anthony M; Fraser, Virginia V; Cook, Judith A

    2010-01-01

    Studies indicate that asset development programs such as Individual Development Accounts (IDAs) can enhance the economic security of low-income populations; however, only a handful of asset development programs have been implemented specifically to serve people with psychiatric disabilities, and larger programs have not collected disability-specific information. The purpose of this article is to increase our knowledge about the use of IDAs to enhance self-determination and recovery for people with psychiatric disabilities. Background information about IDAs is presented followed by case studies of two IDA programs that serve people with psychiatric disabilities. The use of IDA programs in enhancing self-determination among people with psychiatric disabilities is discussed, along with barriers and future directions.

  20. One electron oxidation of Ni(II)-iminodiacetate by carbonate radical

    International Nuclear Information System (INIS)

    Mandal, P.C.; Bardhan, D.K.; Bhattacharyya, S.N.

    1995-01-01

    Reactions of carbonate radical (CO 3 - ), generated by photolysis or by radiolysis of a carbonate solution with nickel(II)-iminodiacetate (Ni(II)IDA) were studied at pH 10.5 and ionic strength (I)=0.2 mol x dm -3 . The stable product arising from the ligand degradation in the complex is mainly glyoxalic acid. Time-resolved spectroscopy and transient kinetics were studied using flash photolysis. From the kinetic data it was suggested that the carbonate radical initially reacts with Ni(III)IDA with a rate constant (2.4.±0.4) x 10 6 dm 3 x mol -1 x s -1 to form a Ni(II)IDA species which, however, undergoes a first-order transformation (k=2.7 x 10 2 x s -1 ) to give a radical intermediate of the type Ni(II)RNHCHCO - 2 ) which rapidly forms an adduct containing a Ni-C bond. This adduct decays very slowly to give rise to glyoxalic acid. From a consideration of equilibrium between Ni(II)IDA and Ni(III)IDA, the one electron reduction potential for the Ni(III)IDA/Ni(II)IDA couple was determined to be 1.467 V. (author) 30 refs.; 5 figs

  1. Clinical Significance of Reticulocyte Hemoglobin Content in the Diagnosis of Iron Deficiency Anemia

    Directory of Open Access Journals (Sweden)

    Mustafa Karagülle

    2013-06-01

    Full Text Available OBJECTIVE: The aim of this study was to evaluate the clinical significance of reticulocyte hemoglobin content (CHr in the diagnosis of iron deficiency anemia (IDA and to compare it with other conventional iron parameters. METHODS: A total of 32 female patients with IDA (serum hemoglobin 120 g/L and serum ferritin <20 ng/mL were enrolled. RESULTS: CHr was 24.95±3.92 pg in female patients with IDA and 29.93±2.96 pg in female patients with iron deficiency. CHr showed a significant positive correlation with hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, serum iron, and transferrin saturation and a significant negative correlation with transferrin and total iron-binding capacity. The cut-off value of CHr for detecting IDA was 29 pg. CONCLUSION: Our data demonstrate that CHr is a useful parameter that can be confidently used in the diagnosis of IDA, and a CHr cut-off value of 29 pg predicts IDA.

  2. Cytarabine and daunorubicin or idarubicin in induction therapy of Acute Myeloid Leukemia patients

    International Nuclear Information System (INIS)

    Eivazi-Ziaei, J.; Kermani, I.A.; Nikanfar, A.; Maljaie, H.; Mahmoudpour, A.; Dolatkhah, R.

    2010-01-01

    Objectives: Acute myeloid leukemia (AML), the most common form of acute leukemia, is treated by remission induction and post-remission therapy. Remission induction is usually achieved by administration of cytarabine along with an anthracycline such as Daunorubicin (DAU) or Idarubicin (IDA). Our objective was see the benefits if any of IDA over DAU in AML therapy. Methodology: Eighty adult AML patients were enrolled in this study, where 40 received DAU and 40 were treated with IDA. Remission status in each subject was studied and response to therapy was subsequently analyzed using SPSS. Results: Complete remission, partial remission and no responsive status were 15, 19, and 14 respectively for patients on DAU and 14, 18, and 11 for patients on IDA protocol. No significant benefit was detected for IDA compared to DAU in response to therapy. Conclusion: We found no benefit in using IDA over DAU in induction therapy for AML patients treated in northwest of Iran. (author)

  3. Siberian population of the New Stone Age: mtDNA haplotype diversity in the ancient population from the Ust'-Ida I burial ground, dated 4020-3210 BC by 14C.

    Science.gov (United States)

    Naumova O, Y u; Rychkov S, Y u

    1998-03-01

    On the basis of analysis of mtDNA from skeletal remains, dated by 14C 4020-3210 BC, from the Ust'-Ida I Neolithic burial ground in Cis-Baikal area of Siberia, we obtained genetic characteristics of the ancient Mongoloid population. Using the 7 restriction enzymes for the analysis of site's polymorphism in 16,106-16,545 region of mtDNA, we studied the structure of the most frequent DNA haplotypes, and estimated the intrapopulational nucleotide diversity of the Neolithic population. Comparison of the Neolithic and modern indigeneous populations from Siberia, Mongolia and Ural showed, that the ancient Siberian population is one of the ancestors of the modern population of Siberia. From genetic distance, in the assumption of constant nucleotide substitution rate, we estimated the divergence time between the Neolithic and the modern Siberian population. This divergence time (5572 years ago) is conformed to the age of skeletal remains (5542-5652 years). With use of the 14C dates of the skeletal remains, nucleotide substitution rate in mtDNA was estimated as 1% sequence divergence for 8938-9115 years.

  4. Iron-Deficiency Anemia in Infancy and Social Emotional Development in Preschool-Aged Chinese Children

    NARCIS (Netherlands)

    Chang, S.; Wang, L.; Wang, Y.; Brouwer, I.D.; Kok, F.J.; Lozoff, B.; Chen, C.

    2011-01-01

    Objective: We aimed to compare affect and behavior of 3 groups of nonanemic 4-year-old children: children with iron-deficiency anemia (IDA) in infancy whose anemia was not corrected before 24 months (chronic IDA) (n = 27); children with IDA in infancy whose anemia was corrected before 24 months

  5. Multilevel index decomposition analysis: Approaches and application

    International Nuclear Information System (INIS)

    Xu, X.Y.; Ang, B.W.

    2014-01-01

    With the growing interest in using the technique of index decomposition analysis (IDA) in energy and energy-related emission studies, such as to analyze the impacts of activity structure change or to track economy-wide energy efficiency trends, the conventional single-level IDA may not be able to meet certain needs in policy analysis. In this paper, some limitations of single-level IDA studies which can be addressed through applying multilevel decomposition analysis are discussed. We then introduce and compare two multilevel decomposition procedures, which are referred to as the multilevel-parallel (M-P) model and the multilevel-hierarchical (M-H) model. The former uses a similar decomposition procedure as in the single-level IDA, while the latter uses a stepwise decomposition procedure. Since the stepwise decomposition procedure is new in the IDA literature, the applicability of the popular IDA methods in the M-H model is discussed and cases where modifications are needed are explained. Numerical examples and application studies using the energy consumption data of the US and China are presented. - Highlights: • We discuss the limitations of single-level decomposition in IDA applied to energy study. • We introduce two multilevel decomposition models, study their features and discuss how they can address the limitations. • To extend from single-level to multilevel analysis, necessary modifications to some popular IDA methods are discussed. • We further discuss the practical significance of the multilevel models and present examples and cases to illustrate

  6. Prevalence of Iron Deficiency Anemia among University Students in Hodeida Province, Yemen

    Directory of Open Access Journals (Sweden)

    Abdullah Ahmed Al-alimi

    2018-01-01

    Full Text Available Background. Iron deficiency anemia (IDA is one of the most common types of nutritional anemia in the worldwide and considered a major public health problem in developing countries especially in Yemen. Therefore, this cross-sectional study was conducted to determine the prevalence and risk factors of IDA among apparently healthy Yemeni students at Hodeida University. Method. Five hundred blood samples (326 males and 174 females were collected randomly from medical students at Hodeida University. Participants were subjected to different tests including complete blood counts (CBC, serum ferritin (SF, serum iron (SI, and total iron binding capacity (TIBC. Moreover, a questionnaire was designed to collect demographics, food and drink habits, and socioeconomic status. Result. The overall prevalence of IDA was 30.4%  (n=152, of whom 54.00% were females (n=82 and 46.0% were males (n=70. Students aged 20–22 years were found more anemic with prevalence 59.2% than students aged 17–19 years (25.0% and 23–25 years (15.8%. Statistical analysis showed regularly having breakfast had significant (p < 0.001 role in preventing development of IDA compared with irregularly having breakfast. Infrequent consumption of vegetables/fruits; meat, fish, chicken; tea drinking; low household income; smoking and khat (Catha edulis chewing showed a significant role (p < 0.001 in provoking of IDA, whereas consumption of coffee and cola showed insignificant influence (p=0.585; p=0.513 on IDA. Conclusion. This study revealed that the majority of university students, especially females, have IDA that might become worse by malnutrition, lifestyle habits, and lack of awareness. Our results suggest that IDA can be prevented by providing proper knowledge on the healthful diet, improved lifestyle, and harmful effect of IDA to the students.

  7. Eesti suurim ettevõte Eesti Energia on KIE regioonis 359.

    Index Scriptorium Estoniae

    2007-01-01

    Ilmunud ka: Finansovõi Menedzhment : infovõpusk nr. 19 nov. lk. 12. Konsultatsioonifirma Deloitte ja Poola majandusajalehe Rzeczpospolita Kesk- ja Ida-Euroopa suurima käibega ettevõtete pingerida. Tabelid: Kesk- ja Ida-Euroopa 8 suurima käibega ettevõtet 2006. aastal; Balti ettevõtted Kesk- ja Ida-Euroopa 500 suurima käibega firma seas

  8. Iron deficiency anemia referral to the hematologist. Real-world data from Mexico: the need for targeted teaching in primary care.

    Science.gov (United States)

    López-García, Yadith Karina; Colunga-Pedraza, Perla Rocío; Tarín-Arzaga, Luz; López Garza, Mariana Itzel; Jaime-Pérez, José Carlos; Gómez-Almaguer, David

    2018-04-11

    To determine the referral patterns and etiology of iron deficiency anemia (IDA) at an academic hematology center in northeast Mexico. We included all consecutive outpatients older than 16 years, non-pregnant, with IDA diagnosed in the Hematology Service of the Dr. José E. González University Hospital between January 2012 and May 2017. Appropriate data were collected retrospectively from the electronic medical record. Data regarding first medical contact (primary care physician or hematologist) were compared. One hundred fifty-three patients were included in this study. The median age was 43 years (interquartile range, 35-51) and 85.6% were female; 128 (83.7%) patients were seen by a primary care physician before our evaluation. Abnormal uterine bleeding (AUB) was the cause of IDA in 76 patients (49.6%), gastrointestinal bleeding (GIB) in 31 (20.2%), H. pylori infection in 12 (7.8%), urinary tract bleeding in three (1.9%) and malabsorption-syndrome in two (1.3%). The etiology remained unknown in 29 (18.9%). The p value was <0.05 between groups according to the first medical contact, including frequency of at least one sign or symptom of IDA, previous use of iron supplementation and blood transfusion, comorbidities, complete blood count at diagnosis, and resolution rates of anemia. The majority of our IDA patients were referred by another physician. Nearly half of the patients with IDA had AUB. IDA remains a diagnostic challenge for first contact physicians requiring a targeted educational intervention to improve IDA awareness and diagnostic skills.

  9. Comparing prevalence of Iron Deficiency Anemia and Beta Thalassemia Trait in microcytic and non-microcytic blood donors: suggested algorithm for donor screening

    Directory of Open Access Journals (Sweden)

    Tiwari Aseem

    2009-01-01

    Full Text Available Background: The prevalence of microcytosis in donors and Iron Deficiency Anemia (IDA and Beta-Thalassemia trait (BTT in microcytic and non-microcytic donors has not been studied in India. The present study aims at finding the same. Materials and Methods: Initially 925 donor samples were evaluated on cell-counter. Of these, 50 were found to be microcytic. These were subjected to Ferritin and HbA2 determination. Subsequently, an additional 51, age-and-sex matched non-microcytic donor samples were selected to serve as controls. These were subjected to the same tests. Results: The prevalence of microcytosis was 5.4% (50/925. Among the microcytic donors, 52% were IDA, 36% BTT, 8% both, and 4% none. In case of non-microcytic donors 29.4% were IDA, 3.9% BTT, and 66.7% none. Conclusions: The study revealed a high prevalence of IDA and BTT in blood donors and a higher probability of finding these in the microcytic samples. This prompted authors to suggest an algorithm for screening of blood donors for IDA and BTT. The algorithm recommends doing an hemogram on all donor samples, routinely. Ferritin could be done only in microcytic samples. At levels lower than15 ng/ml, it is diagnosed as IDA, and therefore, HPLC is performed only for non-IDA samples with Ferritin levels higher than 15 ng/ml. By employing this algorithm, a substantial number of IDA and BTT could be diagnosed while keeping the number of Ferritin tests small and the number of HPLC tests even smaller and thus making it cost efficient.

  10. Donor Interventions and SME Networking in Industrial Clusters in Punjab Province, Pakistan

    DEFF Research Database (Denmark)

    Fayyaz, Anjum

    . Thus, the author seeks to answer two interrelated questions in this thesis: a) How did the IDA interventions affect SME networks in the Lahore garments and Sialkot football clusters in Pakistan? b) Why did the IDA-supported SME networks in these clusters continue or discontinue after the IDA withdrew...... the IDA’s interventions affected the long-term sustainability of SME networks present in both clusters. In the case of the Lahore garments cluster, the IDA supported two networks in the cluster. One was known as the Lahore Garments Consortium and the other was named the Lahore Fashion Apparel Network...

  11. Diagnosis and treatment of iron deficiency anemia during pregnancy and the postpartum period: Iron deficiency anemia working group consensus report

    Science.gov (United States)

    Api, Olus; Breyman, Christian; Çetiner, Mustafa; Demir, Cansun; Ecder, Tevfik

    2015-01-01

    According to the World Health Organization (WHO), anemia is the most common disease, affecting >1.5 billion people worldwide. Furthermore, iron deficiency anemia (IDA) accounts for 50% of cases of anemia. IDA is common during pregnancy and the postpartum period, and can lead to serious maternal and fetal complications. The aim of this report was to present the experiences of a multidisciplinary expert group, and to establish reference guidelines for the optimal diagnosis and treatment of IDA during pregnancy and the postpartum period. Studies and guidelines on the diagnosis and treatment of IDA published in Turkish and international journals were reviewed. Conclusive recommendations were made by an expert panel aiming for a scientific consensus. Measurement of serum ferritin has the highest sensitivity and specificity for diagnosis of IDA unless there is a concurrent inflammatory condition. The lower threshold value for hemoglobin (Hb) in pregnant women is anemia. Oral iron therapy is given as the first-line treatment for IDA. Although current data are limited, intravenous (IV) iron therapy is an alternative therapeutic option in patients who do not respond to oral iron therapy, have adverse reactions, do not comply with oral iron treatment, have a very low Hb concentration, and require rapid iron repletion. IV iron preparations can be safely used for the treatment of IDA during pregnancy and the postpartum period, and are more beneficial than oral iron preparations in specific indications. PMID:28913064

  12. HbA1c and Glycated Albumin Levels Are High in Gastrectomized Subjects with Iron-Deficiency Anemia.

    Science.gov (United States)

    Inada, Shinya; Koga, Masafumi

    2017-01-01

    We report that glycated albumin (GA) is higher relative to HbA1c in non-diabetic, gastrectomized subjects without anemia, and thus is a sign of oxyhyperglycemia. It is known that gastrectomized subjects are prone to iron-deficiency anemia (IDA), and that the HbA1c levels of subjects with IDA are falsely high. In the present study, the HbA1c and GA levels of gastrectomized subjects with IDA were compared with gastrectomized subjects without anemia. Seven non-diabetic gastrectomized subjects with IDA were enrolled in the present study. Twenty-eight non-diabetic gastrectomized subjects without anemia matched with the subjects with IDA in terms of age, gender, and body mass index were used as the controls. Although there were no significant differences in fasting plasma glucose and OGTT 2-hour plasma glucose (2-h PG) between the two groups, the HbA1c and GA levels in gastrectomized subjects with IDA were significantly higher than the controls. For all of the gastrectomized subjects (n=35), ferritin exhibited a significant negative correlation with HbA1c and GA, and a significant positive correlation with 2-h PG. In addition, the HbA1c and GA levels exhibited a significant negative correlation with the mean corpuscular hemoglobin and hemoglobin. The HbA1c and GA levels in gastrectomized subjects with IDA were significantly higher than those in controls. The high GA levels are attributed to a tendency in which patients with total gastrectomy, who are prone to IDA, are susceptible to postprandial hyperglycemia and reactive hypoglycemia, which in turn leads to large fluctuations in plasma glucose. © 2017 by the Association of Clinical Scientists, Inc.

  13. Evaluation of Esophageal Functions by Manometry in Iron Deficiency Anemia Patients.

    Science.gov (United States)

    Kubilay, Pinar; Doganay, Beyza; Bektas, Mehmet

    2017-06-01

    The aim of this study was to investigate whether any esophageal motor dysfunction exists in patients with iron deficiency anemia (IDA). The study included 39 patients (34 women, mean age: 44.17 ± 14.21 years) who met WHO diagnostic criteria for IDA. An additional 30 functional dyspepsia patients were also included as a control group. Esophageal motility testing was performed; esophagus contraction amplitude, peak velocity, contraction time, lower esophageal sphincter (LES) resting pressure, LES relaxation, and LES relaxation duration were assessed. A majority (76.4%) of patients had at least one IDA symptom, such as reflux, chest pain, or dysphagia. Manometric findings in IDA patients vs. controls were as follows: mean LES resting pressure (mm Hg): 25.41 ± 11.67 vs. 19.96 ± 6.58 (P = 0.025); mean esophageal contraction amplitude (mm Hg): 61.61 ± 24.21 vs. 63.23 ± 18.86 (P = 0.764); mean LES relaxation duration (s, x ± SD): 5.33 ± 1.61 vs. 8.75 ± 1.86 (P = 0.000); mean LES relaxation (%): 93.30 ± 9.88 vs. 95.53 ± 5.81 (P = 0.278); mean peak velocity (cm/s): 12.67 ± 37.95 vs. 3.50 ± 1.63 (P = 0.191). Esophageal dysmotility was found in 11 (28.2%) IDA patients. Non-specific esophageal motor disorder was found in three patients, hypomotility of the esophagus was found in three patients, achalasia was found in two patients, hypertensive LES was found in two patients, and hypotensive LES was found in one patient. LES resting pressure was higher and LES relaxation duration was shorter in patients with IDA. Esophageal dysmotility was present in 28.2% of the patients with IDA A little more than half of patients had dysphagia symptoms. IDA may contribute to esophageal motility dysfunction and esophageal symptoms.

  14. Severe iron-deficiency anemia still an issue in toddlers.

    Science.gov (United States)

    Paoletti, Gabrielle; Bogen, Debra L; Ritchey, A Kim

    2014-12-01

    Chronic, severe iron-deficiency anemia (IDA) in the first years of life increases the risk of irreversibly compromised cognitive, affective, and motor development. While IDA in infants has decreased because of dietary changes (iron-fortified formula and delaying cow's milk), toddlers (13-36 months) are equally vulnerable to the adverse effects of IDA. We aimed to show that despite public health efforts, severe IDA remains a problem in toddlers and is associated with excess milk consumption. Retrospective chart review of children 6 to 36 months admitted to or evaluated by hematology at a children's hospital from January 1, 2005 to December 31, 2010 with a severe microcytic anemia (hemoglobin [Hb] appetite, and pica were the most common symptoms, found in 43%, 29%, and 22% of patients, respectively. Only 41% of parents reported pale skin while 77% of physicians recorded it on physical exam. Daily cow's milk consumption surpassed 24 ounces for 47 of 48 children with reported intake; 11 consumed more than 64 ounces per day. Despite current screening recommendations, severe IDA continues to be a problem in toddlers and strongly correlates with excess cow's milk consumption. This reiterates the importance of screening for IDA into routine toddler care. © The Author(s) 2014.

  15. Anemia and iron deficiency in gastrointestinal and liver conditions

    Science.gov (United States)

    Stein, Jürgen; Connor, Susan; Virgin, Garth; Ong, David Eng Hui; Pereyra, Lisandro

    2016-01-01

    Iron deficiency anemia (IDA) is associated with a number of pathological gastrointestinal conditions other than inflammatory bowel disease, and also with liver disorders. Different factors such as chronic bleeding, malabsorption and inflammation may contribute to IDA. Although patients with symptoms of anemia are frequently referred to gastroenterologists, the approach to diagnosis and selection of treatment as well as follow-up measures is not standardized and suboptimal. Iron deficiency, even without anemia, can substantially impact physical and cognitive function and reduce quality of life. Therefore, regular iron status assessment and awareness of the clinical consequences of impaired iron status are critical. While the range of options for treatment of IDA is increasing due to the availability of effective and well-tolerated parenteral iron preparations, a comprehensive overview of IDA and its therapy in patients with gastrointestinal conditions is currently lacking. Furthermore, definitions and assessment of iron status lack harmonization and there is a paucity of expert guidelines on this topic. This review summarizes current thinking concerning IDA as a common co-morbidity in specific gastrointestinal and liver disorders, and thus encourages a more unified treatment approach to anemia and iron deficiency, while offering gastroenterologists guidance on treatment options for IDA in everyday clinical practice. PMID:27672287

  16. Anemia and iron deficiency in gastrointestinal and liver conditions.

    Science.gov (United States)

    Stein, Jürgen; Connor, Susan; Virgin, Garth; Ong, David Eng Hui; Pereyra, Lisandro

    2016-09-21

    Iron deficiency anemia (IDA) is associated with a number of pathological gastrointestinal conditions other than inflammatory bowel disease, and also with liver disorders. Different factors such as chronic bleeding, malabsorption and inflammation may contribute to IDA. Although patients with symptoms of anemia are frequently referred to gastroenterologists, the approach to diagnosis and selection of treatment as well as follow-up measures is not standardized and suboptimal. Iron deficiency, even without anemia, can substantially impact physical and cognitive function and reduce quality of life. Therefore, regular iron status assessment and awareness of the clinical consequences of impaired iron status are critical. While the range of options for treatment of IDA is increasing due to the availability of effective and well-tolerated parenteral iron preparations, a comprehensive overview of IDA and its therapy in patients with gastrointestinal conditions is currently lacking. Furthermore, definitions and assessment of iron status lack harmonization and there is a paucity of expert guidelines on this topic. This review summarizes current thinking concerning IDA as a common co-morbidity in specific gastrointestinal and liver disorders, and thus encourages a more unified treatment approach to anemia and iron deficiency, while offering gastroenterologists guidance on treatment options for IDA in everyday clinical practice.

  17. Experimental and clinical trials of new /sub 99m/Tc-labeled hepatobiliary agents

    International Nuclear Information System (INIS)

    Wistow, B.W.; Subramanian, G.; Gagne, G.M.; Henderson, R.W.; McAfee, J.G.; Hall, R.C.; Grossman, Z.D.

    1978-01-01

    Several new derivatives of lidocaine were synthesized and used to examine the intra- and extrahepatic bile ducts and gallbladder. Diisopropyl-IDA exhibited approximately twice the bile concentration of 131 I-rose bengal during the first hour after injection. P-butyl-IDA also concentrates moderately well in the bile and has the added advantage of very low excretion into the urine (2%). It seems more effective than the other IDA derivatives at high bilirubin levels

  18. Kliimamuutuste mõju laboratoorium / Andres Tarand

    Index Scriptorium Estoniae

    Tarand, Andres, 1940-

    2001-01-01

    Segadused Ida-Aafrika riikides, nende põhjused. Tabel: Ida-Aafrika riikide mõned arengunäitajad: Etioopia, Sudaan, Somaali, Burundi, Rwanda, Uganda, Tanzania, Keenia. Autor: Rahvaerakond Mõõdukad. Parlamendisaadik

  19. Rein Aidma: "Ma ei lähe riigikogusse tukkuma" / Rein Aidma ; interv. Erik Gamzejev

    Index Scriptorium Estoniae

    Aidma, Rein, 1950-

    2003-01-01

    Ilmunud ka: Severnoje Poberezhje : Subbota 15. märts lk. 3. Riigikokku valitud Ida-Viru maavanem Rein Aidma astumisest Reformierakonda, möödunud valimiskampaaniast, Ida-Viru arengut pidurdavatest teguritest

  20. Electrooxidation of C{sub 1} to C{sub 3} alcohols with Pt and Pt-Ru sputter deposited interdigitated array electrodes

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Choong-Gon [Department of Chemical Engineering, Faculty of Engineering, Hanbat National University, San 16-1, Dukmyeong-dong, Yuseong-gu, Daejeon 305-719 (Korea, Republic of)], E-mail: leecg@hanbat.ac.kr; Ojima, Hiroyuki [Department of Applied Chemistry, Graduate School of Engineering, Tohoku University, Aramaki-Aoba 07, Aoba-ku, Sendai 980-8579 (Japan); Umeda, Minoru [Department of Materials Science and Technology, Faculty of Engineering, Nagaoka University of Technology, Kamitomioka 1603-1, Nagaoka, Niigata 940-2188 (Japan)], E-mail: mumeda@vos.nagaokaut.ac.jp

    2008-02-25

    The electrooxidation of methanol, ethanol, and 2-propanol was investigated with interdigitated array electrodes (IDAEs). The IDAE oxidizes alcohol at the generator and reduces the reaction intermediates produced by the oxidation process at the collector. Thus, the reaction intermediates can be estimated with the IDAE. The IDAE in the present work was made of sputter deposited Pt and Pt-Ru. The use of Ru free and added electrodes provides information on the effect of Ru addition on the alcohol oxidation. Cyclic voltammetric analyses revealed that Ru addition enhances the oxidation currents and reduces the E{sub onset} of the alcohols. The detectable reaction intermediate at the methanol and ethanol oxidation was proton, while the intermediate species was acetone in 2-propnaol oxidation.

  1. Student health professionals' attitudes and experience after watching "Ida's Diary", a first-person account of living with borderline personality disorder: Mixed methods study.

    Science.gov (United States)

    Dickens, Geoffrey L; Lamont, Emma; Stirling, Fiona J

    2018-06-01

    There is increasing interest in the use of commercial movies in nursing education, or "cinenurducation". There is a need for educational interventions which target mental health nurses' attitudes towards people with borderline personality disorder. To investigate and evaluate the experience and effects of attendance at a screening of the movie Ida's Diary, a first-person account of living with borderline personality disorder. Mixed methods design comprising a within-subjects AB longitudinal survey, and a qualitative analysis of participant-generated data and researcher field notes from a World Café discussion group. One university in Scotland. N = 66 undergraduate and postgraduate mental health nursing and counselling students. Participants completed measures of cognitive and emotional attitudes towards, and knowledge about, people with borderline personality disorder before and after one of two film screenings. We conducted a World Café discussion group after the second screening. Resulting data were subject to a qualitative thematic analysis. Quantitative analysis revealed a five-factor cognitive and a single-factor emotional attitude structure. Cognitive-attitudinal items related to treatment deservingness and value of mixed treatment approaches improved across iterations. Total knowledge score did not change, but one item about borderline personality disorder as a precursor to schizophrenia received considerably more incorrect endorsement post-screening. Qualitative analysis revealed five themes: Facilitation and inhibition of learning; promotion but not satiation of appetite for knowledge; challenging existing understanding; prompting creativity and anxiety; and initiating thinking about the bigger picture. Participants found the film thought provoking; it increased their appetite for knowledge. Findings suggest that screening should be delivered in conjunction with more didactic information about borderline personality disorder. Copyright © 2018

  2. Isotope dilution analysis of environmental samples

    International Nuclear Information System (INIS)

    Tolgyessy, J.; Lesny, J.; Korenova, Z.; Klas, J.; Klehr, E.H.

    1986-01-01

    Isotope dilution analysis has been used for the determination of several trace elements - especially metals - in a variety of environmental samples, including aerosols, water, soils, biological materials and geological materials. Variations of the basic concept include classical IDA, substoichiometric IDA, and more recently, sub-superequivalence IDA. Each variation has its advantages and limitations. A periodic chart has been used to identify those elements which have been measured in environmental samples using one or more of these methods. (author)

  3. Paha veri / Jan Kaus

    Index Scriptorium Estoniae

    Kaus, Jan, 1971-

    1998-01-01

    Warren Zimmermanni retsensioonist Michael Ignatieffi raamatule "The Warrior's Honour". Külma sõja loodud "tasakaal" aitas vaigistada Ida-Euroopa etnilisi rahutuskoldeid. Etnilised rahutused Kesk- ja Ida-Euroopa 20. saj. lõpus

  4. [Iron-deficiency anaemia in everyday gynaecological practice].

    Science.gov (United States)

    Lukanova, M; Popov, I

    2004-01-01

    Iron-deficiency anaemia /IDA/ is of utmost significance to clinical practice. Chronic haemorrhages from the genital tract are the major etiological factor for its appearance in 60-70% of the patients. Abnormal genital bleeding for the specialist in Obstetrics and gynaecology and IDA for the haematologist are frequently met problems in their everyday practice, which require detailed examination, good colaboration and synchronization between the work of both specialists. Diagnosing and etiological treatment of IDA of gynaecologic origin by mutual timely and adequate co-operation of gynaecologist and haematologist. Clinical survey based on the algorithm worked out. Its everyday application started in July-August 2001 and till today /30.04.2003/ 253 cases with IDA in the Department of Gynaecology are taken in. A record of proceedings was made for every patient and that helped the further diagnostic and therapeutic activity and respective data processing. The data and results obtained verify the achievement of final diagnostic specification of IDA, the role of the algorithm as a stepping-stone to its etiological treatment, complete and durable correction of iron deficiency.

  5. Sleep and Neurofunctions Throughout Child Development: Lasting Effects of Early Iron Deficiency

    Science.gov (United States)

    Peirano, Patricio D.; Algarín, Cecilia R.; Chamorro, Rodrigo; Garrido, Marcelo I.; Lozoff, Betsy

    2013-01-01

    Iron-deficiency anemia (IDA) continues to be the most common single nutrient deficiency in the world. Infants are at particular risk due to rapid growth and limited dietary sources of iron. An estimated 20–25% of the world’s infants have IDA, with at least as many having iron deficiency without anemia. High prevalence is found primarily in developing countries, but also among poor, minority, and immigrant groups in developed ones. Infants with IDA test lower in mental and motor development assessments and show affective differences. After iron therapy, follow-up studies point to long-lasting differences in several domains. Neurofunctional studies showed slower neural transmission in the auditory system despite 1 year of iron therapy in IDA infants; they still had slower transmission in both the auditory and visual systems at preschool age. Different motor activity patterning in all sleep-waking states and several differences in sleep states organization were reported. Persistant sleep and neurofunctional effects could contribute to reduced potential for optimal behavioral and cognitive outcomes in children with a history of IDA. PMID:19214058

  6. Red blood cell distribution width and iron deficiency anemia among pregnant Sudanese women

    Directory of Open Access Journals (Sweden)

    Abdelrahman Esam G

    2012-12-01

    Full Text Available Abstract Background Iron deficiency anemia (IDA is a major health problem during pregnancy and it has adverse effects on the mother and the newborn. Red cell distribution width (RDW, which is a quantitative measure for red cell size variation (anisocytosis, is a predictor of IDA. Little is known regarding RDW and IDA during pregnancy. Methods A cross sectional study was conducted at the antenatal clinic of Khartoum Hospital, Sudan, to determine the performance of RDW in the diagnosis of IDA using serum ferritin as a gold standard. Results Among 194 pregnant women with a gestational period of 21.4 ± 6.5 weeks, 57 (29.4% had IDA according to serum ferritin levels (14.5. The sensitivity, specificity, positive predictive value, and negative predictive value of RDW where serum ferritin was the gold standard were 43.8% (95% CI: 31.4–57.0%, 73.7% (95% CI: 65.8–80.5%, 41.0% (95% CI: 29.2–53.6%, and 76.0% (95% CI: 68.1–82.6%, respectively. Conclusions In this study, we found that RDW has a poor performance in diagnosing IDA among pregnant women compared with serum ferritin as the gold standard. Virtual slides The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1721072967826303

  7. German Unification : the Valuable Lessons / Bernhard Seliger, Ralph M Wrobel

    Index Scriptorium Estoniae

    Seliger, Bernhard

    2000-01-01

    Mida on EL-iga integreeruvatel Baltimaadel õppida Ida-Saksamaa ühinemisest Lääne-Saksamaaga. Rahanduse integreerumine, erastamine, subsideerimine ja palgatõus Saksamaal. Tabelid: Ida-Saksamaa ja Eesti majandusnäitajad 1991-1999

  8. Pro god uhhodjashtshii mõ jeshtsho mozhem skazat "neplohhoi". Kak nazovut god sledujushtshii?

    Index Scriptorium Estoniae

    2008-01-01

    Ida-Virumaa suuremate omavalitsuste juhid Jevgeni Solovjov, Niina Neglasson, Jelena Korshunova ja Mihhail Stalnuhhin ning Ida-Viru maavanem Riho Breivel teevad kokkuvõtteid mööduvast aastast ning heidavad pilgu algavasse aastasse

  9. The association between iron status and some immunological factors in the pregnancy

    Directory of Open Access Journals (Sweden)

    Nadereh Naderi

    2011-01-01

    Full Text Available Iron deficiency anemia (IDA is a common problem in many developing countries. It is still considered the most common nutrition deficiency worldwide. Apart from its direct hematologic importance, IDA affects cellular and humoral immunity and predisposes the host to infections (1.Pregnant women are highly prone to IDA. Controversial results are reported in studies targeting this group of patients. Tang et al showed a direct association between hemoglobin concentration and the count of CD4+ T-cell lymphocytes, serum levels of IL-2 and IgG, and an inverse association with susceptibility to infection (2. Ironically, Leush et al reported an increase in IgM and IgG in the second and third trimesters of pregnancy in women with IDA (3.With regard to controversial results and the scarcity of studies focusing on pregnant women, we aimed to enlighten the relation between iron status and some immunological factors include some component of complement system, IgA, IgM, IgG subclasses of immunoglobulins and pro-inflammatory cytokines during the third trimester of pregnancy.In a descriptive-analytic study participants were recruited using convenient sampling from the women in the third trimester of pregnancyCorresponding author:Nadereh Naderi, Faculty of Medicine, First of Nabovat minicity, opposite of Workers Welfare Community, First of Imam Hossein Blv., Bandarabbas, Iran.Email: msbhnadereh@yahoo.comreferred to the labor room of gynecology and obstetrics ward of Dr. Shariati Hospital of Bandar Abbas, Iran. Patients with signs and symptoms of thalassemia, infectious diseases or autoimmune diseases were excluded.IDA were defined with two criteria, hemoglobin concentration of less than 10 mg/dL (its normal range during the third trimesters of pregnancy is 11-14mg/dL (4 and ferritin less than 40 ng/dL. Patients were categorized into two groups: those with iron deficiency anemia (IDA and those without this condition (no IDA.Red cell indices including hemoglobin

  10. Screening and Treatment for Iron Deficiency Anemia in Women: Results of a Survey of Obstetrician-Gynecologists.

    Science.gov (United States)

    Marcewicz, Lauren H; Anderson, Britta L; Byams, Vanessa R; Grant, Althea M; Schulkin, Jay

    2017-08-01

    Objective To better understand the knowledge, attitudes and practices of obstetrician-gynecologists with respect to screening and treatment for iron deficiency anemia (IDA). Methods A total of 1,200 Fellows and Junior Fellows of the American College of Obstetricians and Gynecologists were invited to participate in a survey on blood disorders. Respondents completed a questionnaire regarding their patient population, screening and treatment practices for IDA, and general knowledge about IDA and its risk factors. Results Overall response rate was 42.4%. Thirty-eight percent of respondents screen non-pregnant patients regularly, based on risk factors; 30.5% screen only when symptoms of anemia are present. For pregnant patients, 50.0% of respondents screen patients at their initial visit, while 46.2% screen every trimester. Sixty-one percent of respondents supplement pregnant patients when there is laboratory evidence of anemia; 31.6% supplement all pregnant patients. Forty-two percent of respondents screen post-partum patients based on their risk factors for IDA. However, when asked to identify risk factors for post-partum anemia, slightly more than half of respondents correctly identified young age and income level as risk factors for post-partum anemia; only 18.9% correctly identified pre-pregnancy obesity as a risk factor. Conclusion There are opportunities for increased education on IDA for obstetrician-gynecologists, specifically with respect to risk factors. There also appears to be substantial practice variance regarding screening and supplementation for IDA, which may correspond to variability in professional guidelines. Increased education on IDA, especially the importance of sociodemographic factors, and further research and effort to standardize guidelines is needed.

  11. Prevalence and determinants of iron deficiency anemia among non-pregnant women of reproductive age in Pakistan.

    Science.gov (United States)

    Habib, Muhammad Atif; Raynes-Greenow, Camille; Soofi, Sajid Bashir; Ali, Noshad; Nausheen, Sidrah; Ahmed, Imran; Bhutta, Zulfiqar Ahmed; Black, Kirsten I

    2018-01-01

    Iron deficiency Anemia (IDA) in women of reproductive age is a recognized public health concern that impairs health and well-being in women and is associated with adverse reproductive outcomes. In Pakistan there is a dearth of up-to-date information on the prevalence and predictors of IDA. This study sought to investigate IDA in Pakistani women. Secondary analysis was performed using the National Nutrition Survey in Pakistan 2011- 2012. We used a pre-structured instrument to collect socio demographic, reproductive and nutritional data on women. We also collected anthropometric measurements and blood samples for micronutrient deficiencies. Univariate and multivariate logistic regression were used to analyse the data. A total of 7491 non-pregnant women aged between 15-49 years were included in the analysis. The prevalence of IDA was 18.1%. In the multivariate regression analysis; not using iron folic acid supplementation during the last pregnancy adjusted odds ratio (AOR) (95% CI) 1.31 (1.05, 1.64), a history of four or more pregnancies AOR (95% CI) 1.30 (1.04, 1.60), birth interval of <24 months AOR (95% CI) 1.27 (1.06, 1.71), household food insecurity AOR (95% CI) 1.42 (1.23, 1.63) and presence of clinical anemia AOR (95% CI) 5.82 (4.82, 7.02) were significantly associated with increased odds of IDA while with obesity AOR (95% CI) 0.60 (0.4, 0.88) showed a protective effect on IDA. To reduce IDA in Pakistani women, the country needs a multifaceted approach that incorporates iron supplementation, food fortification, improved family planning services and efforts to reduce food insecurity.

  12. The role of serum transferrin receptor in the diagnosis of iron deficiency.

    Science.gov (United States)

    Remacha, A F; Sarda, M P; Parellada, M; Ubeda, J; Manteiga, R

    1998-11-01

    Iron deficiency anemia (IDA) is often associated with inflammatory disorders. The most conventional parameters of iron metabolism are therefore affected, making the evaluation of iron status difficult. Serum transferrin receptor (sTfR) levels are raised in iron deficiency but are not influenced by inflammatory changes. The aim of this study was to investigate the role of sTfR in differentiating IDA with inflammatory features. A diagnostic study of sTfR measured by immunoassay was carried out in IDA and anemia of chronic disorders (ACD). The cut-off points of sTfR and the ratio of sTfR/serum ferritin, which were obtained after comparing IDA and ACD, were applied to a group of 64 patients with mixed iron patterns (MIX) (16 with ACD and 48 with IDA). The best cut-off point of sTfR between IDA and ACD was 4.7 mg/L. Applying this cut-off to the MIX group, an efficiency of 87% was obtained (sensitivity 92% and specificity 81%). This level of sTfR correctly classified 53 out of 64 cases of the MIX group (83%). Using the ratio of sTfRx 100/serum ferritin, the best cut-off point was 8 (efficiency 100%), which correctly classified 62 out of 64 cases of the MIX group (97%). This study demonstrates that sTfR in conjunction with other iron parameters is very useful in iron deficiency evaluation, especially in hospital practice. Iron treatment should be considered in patients with mixed patterns of iron status, in which the diagnosis of IDA versus ACD is difficult, when the levels of sTfR exceed the cut-off point.

  13. Diagnosis and treatment of iron deficiency anemia during pregnancy and the postpartum period: Iron deficiency anemia working group consensus report

    Directory of Open Access Journals (Sweden)

    Christian Breyman

    2015-09-01

    Full Text Available According to the World Health Organization (WHO, anemia is the most common disease, affecting >1.5 billion people worldwide. Furthermore, iron deficiency anemia (IDA accounts for 50% of cases of anemia. IDA is common during pregnancy and the postpartum period, and can lead to serious maternal and fetal complications. The aim of this report was to present the experiences of a multidisciplinary expert group, and to establish reference guidelines for the optimal diagnosis and treatment of IDA during pregnancy and the postpartum period. Studies and guidelines on the diagnosis and treatment of IDA published in Turkish and international journals were reviewed. Conclusive recommendations were made by an expert panel aiming for a scientific consensus. Measurement of serum ferritin has the highest sensitivity and specificity for diagnosis of IDA unless there is a concurrent inflammatory condition. The lower threshold value for hemoglobin (Hb in pregnant women is <11 g/dL during the 1st and 3rd trimesters, and <10.5 g/dL during the 2nd trimester. In postpartum period a Hb concentration <10 g/dL indicates clinically significant anemia. Oral iron therapy is given as the first-line treatment for IDA. Although current data are limited, intravenous (IV iron therapy is an alternative therapeutic option in patients who do not respond to oral iron therapy, have adverse reactions, do not comply with oral iron treatment, have a very low Hb concentration, and require rapid iron repletion. IV iron preparations can be safely used for the treatment of IDA during pregnancy and the postpartum period, and are more beneficial than oral iron preparations in specific indications.

  14. Maavanem jagas aumärke / Peeter Lilleväli

    Index Scriptorium Estoniae

    Lilleväli, Peeter

    2001-01-01

    Ida-Virumaa maavanem Rein Aidma jagas nii riiklikke autasusid kui ka Ida-Virumaa teenetemärke. Vastuvõtul viibis ka USA suursaadik Eestis Mellissa Wells. Ilmunud ka: Severnoje Poberezhje, 27. veebr. 2001, lk. 1

  15. Kommunikatsioonijuht saab aidata arsti ja patsienti / Eda Amur, Anneli Bogens, Svea Talving, Krista Valdvee ; intervjueerinud Küllike Heide

    Index Scriptorium Estoniae

    2013-01-01

    Meditsiinivaldkonna kommunikatsiooniga seotud küsimuste ja probleemide üle arutlevad nelja haigla kommunikatsioonijuhid: Eda Amur Pärnu haiglast, Anneli Bogens Ida-Viru keskhaiglast, Svea Talving Ida-Tallinna keskhaiglast ning Krista Valdvee Viljandi haiglast

  16. Pathways to Higher Education for Native Hawaiian Individual Development Account Participants

    Directory of Open Access Journals (Sweden)

    David W. Rothwell

    2013-11-01

    Full Text Available As the cost of higher education rises, a growing body of theory and research suggests that asset holding in the form of savings and net worth positively influence education expectations and outcomes. Native Hawaiians, like other Indigenous peoples, have disproportionately low college enrollment and graduation rates tied to a history of colonization. Using data from an Individual Development Account (IDA program for Native Hawaiians, I examine the trajectories through the program and find: (a welfare receipt and unemployment reduces the chances of IDA enrollment; (b net worth increases the probability of IDA graduation; and (c IDA graduates were more likely to gain a college degree over time compared to non-graduates. The study provides empirical evidence to the debate on asset-based interventions for Indigenous peoples.

  17. Via Hanseatica arendamine on saadikute tähelepanu all / Rein Aidma

    Index Scriptorium Estoniae

    Aidma, Rein, 1950-

    2006-01-01

    Ilmunud ka: Severnoje Poberezhje 11. apr. lk. 2. Riigikogu Ida-Viru saadikuühendus kohtus Ida-Viru, Jõgeva, Tartu ja Valga maavalitsuse spetsialistidega arutamaks Via Hanseatica e. Jõhvi-Tartu-Valga majandusvööndi arenguvõimalusi

  18. Endoscopic resection of large colonic lipomas assisted by a prototype single-use endoloop device

    Directory of Open Access Journals (Sweden)

    Ahmad Khosravi Khorashad

    2011-01-01

    Full Text Available Colonic lipomas are benign adipose tumors that do not usually cause symptoms. Giant colonic lipoma (GCL is an uncommon finding at endoscopy which may lead to iron deficiency anemia (IDA with or without macroscopic ulceration. The choice of therapeutic procedure to treat symptomatic GCLs has been controversial. A case of GCL presented with occult bleeding and IDA is reported in this article. IDA resolved following the successful removal of the GCL by a combination of endoloop ligation and snare cautery technique.

  19. Aerospace System Unified Life Cycle Engineering Producibility Measurement Issues

    Science.gov (United States)

    1989-05-01

    High Energy Forming Electrochemical Mechanical Fastening Knurling Rubber Pad Forming Electrical Discharge Painting Hydroforming Electron Beam...ICan I neml Implolicd... IDA ItepoIan m ieswed by outid ponels of I -rt o esn their high quait and resneto the pro m Shadow. aMd t e okmied by thne...ul bete ubec o m iDAR IeprI IDA O Go p, I arm lewod by the seio Individuals repnI, l letthe pojctadm ohs n selecied by IDA to esmur air high quality

  20. Delta-He, Ret-He and a New Diagnostic Plot for Differential Diagnosis and Therapy Monitoring of Patients Suffering from Various Disease-Specific Types of Anemia.

    Science.gov (United States)

    Weimann, Andreas; Cremer, Malte; Hernáiz-Driever, Pablo; Zimmermann, Mathias

    2016-01-01

    The present study was aimed to prove the usefulness of a new diagnostic plot (Hema-Plot), illustrating the relationship between the hemoglobin content of reticulocytes (Ret-He) as a marker of functional iron deficiency and the difference between the reticulocyte and erythrocyte hemoglobin content (Delta-He) as a marker of an impaired hemoglobinization of newly formed reticulocytes occurring during inflammatory processes, to differentiate between various disease-specific types of anemia. A complete blood and reticulocyte count was performed on routine EDTA blood samples from 345 patients with and without various disease-specific types of anemia using the Sysmex XN-9000 hematology analyzer: blood healthy newborns (n = 23), blood healthy adults (n = 31), patients suffering from anemia of chronic disease (ACD) due to diverse oncological, chronic inflammatory, or autoimmune diseases (total n = 138) with (n = 65) and without therapy (n = 73), patients with thalassemia and/or hemoglobinopathy (n = 18), patients with iron deficiency anemia (IDA) (n = 35), patients with a combination of ACD and IDA (n = 17), as well as patients suffering from sepsis (total n = 83) with (n = 32) and without therapy (n = 51). The results for Ret-He, Delta-He, and C-reactive protein (CRP) were statistically compared (Mann-Whitney U Test) between the particular patient groups and the diagnostic plots were drawn. Delta-Hemoglobin showed a statistically significant difference between blood healthy newborns and blood healthy adults (p ≤ 0.05), while Ret-He and C-reactive protein did not. In addition, of all three biomarkers only Delta-He showed a statistically significant difference (p ≤ 0.05) between the ACD/IDA and IDA cohort. Delta-He, Ret-He, and CRP showed a statistically significant difference between patient cohorts with and without therapy suffering from ACD, ACD/IDA, and sepsis before and after medical therapy (p ≤ 0.05). The Hema-Plot illustrated the dynamic character of Ret-He and

  1. Prepartum anaemia: prevention and treatment.

    Science.gov (United States)

    Milman, Nils

    2008-12-01

    This review focuses on the occurrence, prevention and treatment of anaemia during pregnancy in Western societies. Iron deficiency anaemia (IDA) is the most prevalent deficiency disorder and the most frequent form of anaemia in pregnant women. Minor causes of anaemia are folate and vitamin B12 deficiency, haemoglobinopathy and haemolytic anaemia. Anaemia is defined as haemoglobin of pregnancy. The prevalence of prepartum anaemia in the third trimester ranges 14-52% in women taking placebo and 0-25% in women taking iron supplements, dependent on the doses of iron. In studies incorporating serum ferritin, the frequency of IDA in placebo-treated women ranges 12-17% and in iron-supplemented women 0-3%. Requirements for absorbed iron increase during pregnancy from 0.8 mg/day in the first trimester to 7.5 mg/day in the third trimester, on the average approximately 4.4 mg/day, and dietary measures are inadequate to reduce the frequency of prepartum IDA. However, IDA is efficiently prevented by oral iron supplements in doses of 30-40 mg ferrous iron taken between meals from early pregnancy to delivery. Treatment of IDA should aim at replenishing body iron deficits by oral and/or intravenous administration of iron. In women with slight to moderate IDA, i.e. haemoglobin of 90-105 g/L, treatment with oral ferrous iron of approximately 100 mg/day between meals is the therapeutic option in the first and second trimester; haemoglobin should be checked after 2 weeks and provided an increase of >or=10 g/L, oral iron therapy has proved effective and should continue. Treatment with intravenous iron is superior to oral iron with respect to the haematological response. Intravenous iron is considered safe in the second and third trimester, while there is little experience in the first trimester. Intravenous iron of 600-1,200 mg should be considered: (1) as second option if oral iron fails to increase haemoglobin within 2 weeks; (2) as first option at profound IDA, i.e. haemoglobin of

  2. Improved differential diagnosis of anemia of chronic disease and iron deficiency anemia: a prospective multicenter evaluation of soluble transferrin receptor and the sTfR/log ferritin index.

    Science.gov (United States)

    Skikne, Barry S; Punnonen, Kari; Caldron, Paul H; Bennett, Michael T; Rehu, Mari; Gasior, Gail H; Chamberlin, Janna S; Sullivan, Linda A; Bray, Kurtis R; Southwick, Paula C

    2011-11-01

    Anemia of chronic disease (ACD) and iron deficiency anemia (IDA) are the most prevalent forms of anemia and often occur concurrently. Standard tests of iron status used in differential diagnosis are affected by inflammation, hindering clinical interpretation. In contrast, soluble transferrin receptor (sTfR) indicates iron deficiency and is unaffected by inflammation. Objectives of this prospective multicenter clinical trial were to evaluate and compare the diagnostic accuracy of sTfR and the sTfR/log ferritin index (sTfR Index) for differential diagnosis using the automated Access(®) sTfR assay (Beckman Coulter) and sTfR Index. We consecutively enrolled 145 anemic patients with common disorders associated with IDA and ACD. Subjects with IDA or ACD + IDA had significantly higher sTfR and sTfR Index values than subjects with ACD (P < 0.0001). ROC curves produced the following cutoffs for sTfR: 21 nmol/L (or 1.55 mg/L), and the sTfR Index: 14 (using nmol/L) (or 1.03 using mg/L). The sTfR Index was superior to sTfR (AUC 0.87 vs. 0.74, P < 0.0001). Use of all three parameters in combination more than doubled the detection of IDA, from 41% (ferritin alone) to 92% (ferritin, sTfR, sTfR Index). Use of sTfR and the sTfR Index improves detection of IDA, particularly in situations where routine markers provide equivocal results. Findings demonstrate a significant advantage in the simultaneous determination of ferritin, sTfR and sTfR Index. Obtaining a ferritin level alone may delay diagnosis of combined IDA and ACD. Copyright © 2011 Wiley-Liss, Inc.

  3. Comparison of /sup 99m/Tc diethyl-iminodiacetic acid and 131I rose bengal for hepatobiliary studies in liver-transplant patients: concise communication

    International Nuclear Information System (INIS)

    Klingensmith, W.C. III; Fritzberg, A.R.; Koep, L.J.

    1979-01-01

    Previous animal studies indicate that technetium-99m N,α-(2,6-diethylacetanilide)-iminodiacetic acid (/sup 99m/Tc diethyl-IDA) is superior to 131 I rose bengal ( 131 I RB) in most, but not all, physiologic parameters. Technetium-99m diethyl-IDA has a faster blood clearance, greater hepatic clearance, and a shorter hepatocyte transit time, but 131 I RB exhibits less renal clearance. We evaluated the relative merits of /sup 99m/Tc-diethyl-IDA and 131 I RB in paired studies in ten liver-transplant patients. Technetium-99m diethyl-IDA images were superior to 131 I RB images in demonstrating: (1) the liver parenchyma, (2) intrahepatic ducts, (3) small-bowel activity early after injection, and (4) in a smaller number of comparisons, colonic activity at 24 hr after injection. In addition, the percentage of dose excreted in the urine in 3 h for both radiopharmaceuticals was measured in 19 patients (total serum bilirubin range: 0.5 to 22.4 mg/dl). The percentage of dose of/sup 99m/Tc diethyl-IDA excreted in the urine averaged 7.5 in patients with normal total bilirubin levels and increased significantly with increasing total bilirubin levels. In the case of 131 I RB, normal patients averaged 4.9% of the injected dose in the urine and there was no increase with increasing total bilirubin levels. It is concluded that (1) /sup 99m/TC diethyl-IDA is superior to 131 I RB for imaging the hepatobiliary system, and (2) renal excretion of 131 I RB, unlike that of /sup 99m/Tc diethyl-IDA, is relatively unaffected by the total serum bilirubin level during the first 3 h after injection

  4. Better differential diagnosis of iron deficiency anemia from beta-thalassemia trait

    Directory of Open Access Journals (Sweden)

    Fakher Rahim

    2009-09-01

    Full Text Available Objective: Iron deficiency anemia (IDA and beta-thalassemia trait (ß-TT are the most common forms of microcytic anemia. This study was conducted to compare the validity of various discrimination indices in differentiating β-TT from IDA by calculating their sensitivity, specificity and Youden's index.Methods: Totally 323 subjects (173 children and 150 adults with microcytic anemia were involved in this study. We calculated 10 discrimination indices in all patients with IDA and β-TT. We divided the patients into two different groups as younger or older than 10 years. Results: None of the indices showed sensitivity and specificity of 100% in the patients older than 10 years, and in the patients younger than 10 years, only Shine & Lal index showed sensitivity close to 90% and specificity of 100%. The most accurate discriminative index for patients younger than 10 years was Shine & Lal and for those older than 10 years it was RDW index. According to Youden's index, Shine & Lal and RBC count showed the greatest diagnostic value in patients younger than 10 years and RDW and RBC count indices in those older than 10 years. Conclusion: None of the indices was completely sensitive and specific in differentiation between β-TT and IDA. Mean and median mean cell Hb density (MCHD were very close to normal values in both IDA and β-TT patients, but in the case of mean density of Hb/liter (MDHL, we found that the mean and median were significantly higher than normal values in β-TT and lower than normal values in IDA patients. In our study, Youden's index of RBC and Shine & Lal were the highest and most reliable indices in differentiating β-TT from IDA in the patients younger than 10 years. For patients older than 10 years, the most reliable discrimination indices were RBC and RDW.

  5. Iron deficiency anemia in inflammatory bowel disease

    Science.gov (United States)

    Kaitha, Sindhu; Bashir, Muhammad; Ali, Tauseef

    2015-01-01

    Anemia is a common extraintestinal manifestation of inflammatory bowel disease (IBD) and is frequently overlooked as a complication. Patients with IBD are commonly found to have iron deficiency anemia (IDA) secondary to chronic blood loss, and impaired iron absorption due to tissue inflammation. Patients with iron deficiency may not always manifest with signs and symptoms; so, hemoglobin levels in patients with IBD must be regularly monitored for earlier detection of anemia. IDA in IBD is associated with poor quality of life, necessitating prompt diagnosis and appropriate treatment. IDA is often associated with inflammation in patients with IBD. Thus, commonly used laboratory parameters are inadequate to diagnose IDA, and newer iron indices, such as reticulocyte hemoglobin content or percentage of hypochromic red cells or zinc protoporphyrin, are required to differentiate IDA from anemia of chronic disease. Oral iron preparations are available and are used in patients with mild disease activity. These preparations are inexpensive and convenient, but can produce gastrointestinal side effects, such as abdominal pain and diarrhea, that limit their use and patient compliance. These preparations are partly absorbed due to inflammation. Non-absorbed iron can be toxic and worsen IBD disease activity. Although cost-effective intravenous iron formulations are widely available and have improved safety profiles, physicians are reluctant to use them. We present a review of the pathophysiologic mechanisms of IDA in IBD, improved diagnostic and therapeutic strategies, efficacy, and safety of iron replacement in IBD. PMID:26301120

  6. Treatment for spontaneous intracranial dissecting aneurysms in childhood: a retrospective study of 26 cases

    Directory of Open Access Journals (Sweden)

    Yisen Zhang

    2016-12-01

    Full Text Available Objective This study aimed to assess the clinicoradiological features and treatment outcome of intracranial dissecting aneurysms (IDAs in childhood.Methods We conducted a retrospective study of pediatric patients who were treated for spontaneous IDAs in our institute between January 2010 and December 2015. The clinical presentation, aneurysm characteristics, treatment modality, and outcome were studied. Results We studied 26 pediatric patients (mean age, 13.4 years; range, 4–18 years with 31 IDAs who comprised 6.9% of all IDA patients treated during the same period. Seventeen (65.4% patients were male and nine (34.6% were female. The incidence of large (≥10mm in size or giant aneurysms (≥25mm in size was 65.5%. Twenty-one (80.8% patients underwent endovascular or surgical treatment and five (19.2% received conservative treatment. Perioperative complications occurred in three patients, in whom two eventually recovered completely with a Glasgow Outcome Scale (GOS score of 5 and one partially recovered with a GOS score 4. Overall, 25 (96.2% patients had a favorable outcome and one (3.8% had an unfavorable outcome at a mean follow-up of 22.8 months (range, 6–60 months.Conclusions Pediatric IDAs are rare. In this series, endovascular management was a relatively safe and effective method of treatment for pediatric IDAs. However, continued follow-up is required because of the possibility of aneurysm recurrence and de novo aneurysm formation after treatment.

  7. Järjekord liival / Stanley Reed, Emily Thornton, Eamon Javers

    Index Scriptorium Estoniae

    Reed, Stanley

    2007-01-01

    USA ärimeeste visiitidest Lähis-Ida naftariikidesse, mille eesmärkideks on võita kohalike juhtide soosing ning sõlmida endale võimalikult suuri ja kasulikke tehinguid. Diagramm: Lähis-Ida tehingute maht. Lisa: Külaliste nimekiri

  8. Developing Near Real-time Data-assimilative Models and Tools for the Space Environment, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The IDA4D and AMIE data assimilation methods are currently of limited use for real-time space weather applications because either they don't run in real-time (IDA4D)...

  9. Eesti ehitusturu kasv tipneb 2006. aastal / Ain Hinsberg

    Index Scriptorium Estoniae

    Hinsberg, Ain

    2002-01-01

    Taanis asuva uuringufirma European Construction Research, mis jälgib ja prognoosib Ida- ja Lääne-Euroopa ning Lähis-Ida, Hiina ja Aasia ehitusturgu, ennustab Eestile jätkuvat kasvu. Diagramm: Eesti ehitusturu areng 1999-2010

  10. Krazh v regione stalo menshe. Prestuplenii protiv litshnosti - bolshe / Kalev Prillop ; interv. Aleksei Starkov

    Index Scriptorium Estoniae

    Prillop, Kalev

    2006-01-01

    Ilmunud ka: Infopress 11. aug. lk. 24-25. Ida politseiprefekt vastab küsimustele, mis puudutavad Sillamäe elaniku tapmist Narva-Jõesuus, kuritegevust Ida- ja Lääne-Virumaal selle aasta I poolaastal, sh. Sillamäel

  11. Synthesis and selective IR absorption properties of iminodiacetic-acid intercalated MgAl-layered double hydroxide

    International Nuclear Information System (INIS)

    Wang Lijing; Xu Xiangyu; Evans, David G.; Duan Xue; Li Dianqing

    2010-01-01

    An MgAl-NO 3 -layered double hydroxide (LDH) precursor has been prepared by a method involving separate nucleation and aging steps (SNAS). Reaction with iminodiacetic acid (IDA) under weakly acidic conditions led to the replacement of the interlayer nitrate anions by iminodiacetic acid anions. The product was characterized by XRD, FT-IR, TG-DTA, ICP, elemental analysis and SEM. The results show that the original interlayer nitrate anions of LDHs precursor were replaced by iminodiacetic acid anions and that the resulting intercalation product MgAl-IDA-LDH has an ordered crystalline structure. MgAl-IDA-LDH was mixed with low density polyethylene (LDPE) using a masterbatch method. LDPE films filled with MgAl-IDA-LDH showed a higher mid to far infrared absorption than films filled with MgAl-CO 3 -LDH in the 7-25 μm range, particularly in the key 9-11 μm range required for application in agricultural plastic films. - Graphical abstract: Intercalation of iminodiacetic acid (IDA) anions in a MgAl-NO 3 -layered double hydroxide host leads to an enhancement of its infrared absorbing ability for application in agricultural plastic films.

  12. Occupational exposure in a commercial nuclear pharmacy

    International Nuclear Information System (INIS)

    Fernandez, J.; Ruiz, A.; Baro, J.; Piera, C.; Ramirez de Arellano, I.

    2002-01-01

    Central Radiopharmacy Services (CRS) prepare radiopharmaceuticals in individual dispensed activity (IDA) and deliver them to different Nuclear Medicine Services. CADISA is a CRS which approximately produces 100,000 IDA per year. The ALARA principle was first present during the facility design. The distribution, shielding and dimensions of the different areas were chosen to provide ergonomic and well protected working places. This design together with good laboratory practices and personal training have led to a reasonably low collective dose due to external exposure. During the first working year, 1996, the collective dose per IDA was 0.45 μSv-man. In the following years, due to some design improvement and mainly to the skill of personnel, this indicator has hand an asymptotical reduction. In 2001 its value has been of 0.18μSv-man/IDA. (Author)

  13. /sup 99m/Tc-labelled hepatobiliary radiopharmaceuticals

    International Nuclear Information System (INIS)

    Galli, G.; Maini, C.L.

    1986-01-01

    During the last 15 years many compounds labelled with /sup 99m/Tc have been proposed for use in cholescintigraphy. A short chronological list includes: toluidine blue, penicillamine, tetracycline, dihydrothioctic acid, mercaptoisubutyric acid, pyridoxals, pyridoxylideneaminates, carboxyl-hydroxyquinoline, substituted acetanilide iminodiacetates (so called IDAs), ethylenediamine-N, N-diacetate derivatives (such as sulfonyl-EDDA and benzoyl-EDDA), and orthoiodohippurate analogues. Among all these compounds the IDAs have been those most extensively used for basic and clinical research. A large series of IDA derivatives has been developed, and the properties of 33 of them have recently been tested

  14. Winners and losers in transition: preferences for redistribution and nostalgia for communism in Eastern Europe / Adam Okulicz- Kozaryn

    Index Scriptorium Estoniae

    Okulicz- Kozaryn, Adam

    2014-01-01

    Artikli teema on üleminekuperioodi võitjad ja kaotajad Ida-Euroopas (sh. Eesti), täpsemalt käsitletakse nostalgiat kommunismi järele. Andmed pärinevad uurimusest „Demokraatia konsolideerumine Kesk- ja Ida-Euroopas 1990-2001”.

  15. Audit Oversight: Quality Control Review of PricewaterhouseCoopers, LLP and the Defense Contract Audit Agency Office of Management and Budget Circular A-133 Audit Report of the Institute for Defense Analyses, Fiscal Year Ended September 28, 2001

    National Research Council Canada - National Science Library

    Davis, Carolyn R; Stern, Janet; Rainey, Laura A; Harrigan, Monica M; Harris, Ashley

    2004-01-01

    IDA is a not-for-profit organization that manages DoD-sponsored FFRDCs. Founded in 1947 as the Weapons Systems Evaluation Group, IDA was incorporated in 1956 and has its headquarters in Alexandria, Virginia, with sites in Norfolk, Virginia...

  16. Unicredit: Eestil on vundament korras / Fabio Mucci ; intervjueerinud Villu Zirnask

    Index Scriptorium Estoniae

    Mucci, Fabio

    2011-01-01

    Intervjuu Unicredit Groupi Kesk- ja Ida-Euroopa pangandusanalüüsi osakonna juhatajaga. Tema sõnul on võrreldes teiste Kesk- ja Ida-Euroopa riikidega Eesti lähemate aastate väljavaated suhteliselt head, sest makromajanduslik vundament on meil korras

  17. Caregiver perceptions of iron deficiency anemia and iron replacement therapies in young children with nutritional iron deficiency anemia

    Science.gov (United States)

    In the U.S., approximately 3% of young children develop iron deficiency anemia (IDA), with Hispanic/Latino children disproportionately affected. IDA is associated with inferior neurodevelopmental outcomes. Treatment with oral iron mitigates its consequences yet non-adherence often results in treatme...

  18. Egg Yolk Protein Delays Recovery while Ovalbumin Is Useful in Recovery from Iron Deficiency Anemia

    Directory of Open Access Journals (Sweden)

    Yukiko Kobayashi

    2015-06-01

    Full Text Available Protein is a main nutrient involved in overall iron metabolism in vivo. In order to assess the prevention of iron deficiency anemia (IDA by diet, it is necessary to confirm the influence of dietary protein, which coexists with iron, on iron bioavailability. We investigated the usefulness of the egg structural protein in recovery from IDA. Thirty-one female Sprague-Dawley rats were divided into a control group (n = 6 fed a casein diet (4.0 mg Fe/100 g for 42 days and an IDA model group (n = 25 created by feeding a low-iron casein diet (LI, 0.4 mg Fe/100 g for 21 days and these IDA rats were fed normal iron diet with different proteins from eggs for another 21 days. The IDA rats were further divided into four subgroups depending on the proteins fed during the last 21 days, which were those with an egg white diet (LI-W, 4.0 mg Fe/100 g, n = 6, those with an ovalbumin diet (LI-A, 4.0 mg Fe/100 g, n = 7, those with an egg yolk-supplemented diet (LI-Y, 4.0 mg Fe/100 g, n = 6, and the rest with a casein diet (LI-C, 4.0 mg Fe/100 g, n = 6. In the LI-Y group, recovery of the hematocrit, hemoglobin, transferrin saturation level and the hepatic iron content were delayed compared to the other groups (p < 0.01, 0.01, 0.01, and 0.05, respectively, resulting in no recovery from IDA at the end of the experimental period. There were no significant differences in blood parameters in the LI-W and LI-A groups compared to the control group. The hepatic iron content of the LI-W and LI-A groups was higher than that of the LI-C group (p < 0.05. We found that egg white protein was useful for recovery from IDA and one of the efficacious components was ovalbumin, while egg yolk protein delayed recovery of IDA. This study demonstrates, therefore, that bioavailability of dietary iron varies depending on the source of dietary protein.

  19. Reticulocyte haemoglobin content as a diagnostic tool for iron ...

    African Journals Online (AJOL)

    IDA) in ill children is complicated by the unreliability of serum ferritin (S-ferritin). The presence of a microcytic, hypochromic anaemia suggests IDA but is not specific. There is a need for a diagnostic test that will be accessible, cost-effective and ...

  20. E-tervishoiust on abi kõigile / Kai Ilustrumm

    Index Scriptorium Estoniae

    Ilustrumm, Kai

    2004-01-01

    Vt. ka Linnaleht : Pärnu : Tehnika, Linnaleht : Tartu : Tehnika 5. nov., lk. 10. Ida-Tallinna Keskhaigla on haaratud Taani, Norra, Rootsi, Eesti ja Leedu tervishoiualasesse koostööprojekti Baltic eHealth ehk Balti e-tervishoid. Ida-Tallinna Keskhaiglasse rajatakse rahvusvaheline radioloogiakeskus

  1. Arno Rossman: "Paksu nahata põled poliitikas kiiresti läbi" / Arno Rossman ; interv. Erik Gamzejev

    Index Scriptorium Estoniae

    Rossman, Arno, 1954-

    2006-01-01

    Ilmunud ka: Severnoje Poberezhje Ilmunud ka: Severnoje Poberezhje : Subbota 4. nov. lk. 3. Keskkonnaministri nõunik oma tööst ning tulevastest parlamendivalimistest. Lisa: Arno Rossman. Arvamust avaldavad Ida-Virumaa omavalitsuste liidu tegevdirektor Urve Erikson ja Ida-Viru spordiliidu esimees Valdek Murd

  2. The Creativity Passdown Effect

    DEFF Research Database (Denmark)

    Pries-Heje, Jan

    2015-01-01

    Purpose – The purpose of this paper is to suggest that translating a design theory (DT) into practice (e.g. creating an instance design artifact (IDA)) is hardly straight-forward and requires substantial creativity. Specifically the authors suggest that adopting a DT embodies a creativity passdown...... effect in which the creative thinking of a team of design theorist(s) inherent in DT invokes a creative mind of a team of artifact instance designer(s) in creating an IDA. In this study, the authors empirically investigate the creativity passdown effect through an action case in which a DT (DT nexus...... designer team introducing a previously published DT as a basis for creating an IDA. Findings – The experience in the action case suggests that using a DT in creating an IDA may encourage design thinking, and in certain way increase its power and practical relevance by fostering the creative mind...

  3. Iron Deficiency Anemia in Adolescents Who Present with Heavy Menstrual Bleeding.

    Science.gov (United States)

    Cooke, Amanda G; McCavit, Timothy L; Buchanan, George R; Powers, Jacquelyn M

    2017-04-01

    To assess the clinical severity and initial treatment of iron deficiency anemia (IDA) in female adolescents with heavy menstrual bleeding (HMB) in our center. Retrospective cohort study of electronic medical records via search of administrative records using International Classification of Diseases Ninth Revision codes for IDA or unspecified anemia and disorders of menstruation. Children's Medical Center in Dallas, Texas. One hundred seven patients with HMB and concomitant IDA (median age, 14.4 years) who presented to the outpatient, emergency department, and/or inpatient settings. The median initial hemoglobin concentration for all patients (n = 107) was 7.4 g/dL, and most (74%, n = 79) presented to the emergency department or via inpatient transfer. Symptomatic IDA was treated with blood transfusion in 46 (43%, n = 46). Ferrous sulfate was the most commonly prescribed oral iron therapy. Seven patients received intravenous iron therapy either initially or after oral iron treatment failure. Combined oral contraceptives were commonly prescribed for abnormal uterine bleeding, yet 10% of patients (n = 11) received no hormonal therapy during their initial management. Evaluation for underlying bleeding disorders was inconsistent. Severe anemia because of IDA and HMB resulting in urgent medical care, including hospitalization and blood transfusion, is a common but underemphasized problem in adolescent girls. In addition to prevention and early diagnosis, meaningful efforts to improve initial management of adolescents with severe HMB and IDA are necessary. Copyright © 2016 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

  4. Expression of Duodenal Iron Transporter Proteins in Diabetic Patients with and without Iron Deficiency Anemia

    Directory of Open Access Journals (Sweden)

    Efrat Broide

    2018-01-01

    Full Text Available The role of iron transport proteins in the pathogenesis of anemia in patients with diabetes mellitus (T2DM is still unclear. We investigated the expression of duodenal transporter proteins in diabetic patients with and without iron deficiency anemia (IDA. Methods. Overall, 39 patients were included: 16 with T2DM and IDA (group A, 11 with T2DM without IDA (group B, and 12 controls (group C. Duodenal mucosal expression of divalent metal transporter 1 (DMT1, ferroportin 1 (FPN, hephaestin (HEPH, and transferrin receptor 1 (TfR was evaluated by Western blotting. Chronic disease activity markers were measured as well. Results. FPN expression was increased in group A compared to group B and controls: 1.17 (0.72–1.46, 0.76 (0.53–1.04, and 0.71 (0.64–0.86, respectively (p=0.011. TfR levels were over expressed in groups A and B compared to controls: 0.39 (0.26–0.61, 0.36 (0.24–0.43, and 0.18 (0.16–0.24, respectively, (p=0.004. The three groups did not differ significantly with regard to cellular HEPH and DMT1 expression. The normal CRP and serum ferritin levels, accompanied with normal FPN among diabetic patients without IDA, do not support the association of IDA with chronic inflammatory state. Conclusion. In patients with T2DM and IDA, duodenal iron transport protein expression might be dependent on body iron stores rather than by chronic inflammation or diabetes per se.

  5. IVEK koolitab vabaühendusi

    Index Scriptorium Estoniae

    2005-01-01

    Ilmunud ka: Severnoje Poberezhje : Ida-Viruskii tsentr predprinimatelstva Info 10. sets., lk. 4. Mittetulundusühendused ja sihtasutused saavad Ida-Viru ettevõtluskeskusest infot nii tegevuse alustamiseks, ideede arendamiseks kui projektide ja arenguplaani koostamiseks. Vt. samas: mittetulundusühingute/sihtasutuste nõustaja Krista Pedak

  6. На сцене сойдутся Восток и Запад / Лилия Крысина

    Index Scriptorium Estoniae

    Крысина, Лилия

    2010-01-01

    Koreograafid-tantsijad Külli Roosna ja Anna esitavad Tallinnas ja Tartus oma soolo-tantsuetenduse, milles ühinevad Ida ja Lääs. Läänt esindab Külli Roosna (Eesti) "Circle Through" ja Ida esindab Anna (Jaapan) "Busu". Organisaatoriks on Sõltumatu Tantsu Ühendus

  7. Illuka kool uuris Kurtna järvistut / Emilia Landra

    Index Scriptorium Estoniae

    Landra, Emilia

    2001-01-01

    Kuidas on mõjutanud põlevkivitööstus, briketitootmine, liivakarjääri rajamine ja Ida-Virumaa linnade veega varustamine Kurtna järvistut? Sellest küsimusest ajendatuna tekkis Illuka Põhikoolil mõte koostada projekt ja esitada see rahastamiseks Ida-Virumaa Keskkonnateenistusele

  8. SEISMIC PERFORMANCE OF MOMENT-RESISTING CONCRETE FRAMES SUBJECTED TO EARTHQUAKE EXCITATION

    Directory of Open Access Journals (Sweden)

    FADZLI MOHAMED NAZRI

    2014-12-01

    Full Text Available In this study, moment-resisting concrete frames (MRCFs were designed based on Eurocodes 2 and 8, which indicate the seismic provisions and requirements for building design and construction. This study aims to investigate the damage measure of MRCFs subjected to earthquake excitation by pushover analysis (POA and incremental dynamic analysis (IDA. In POA, inverted triangular lateral load and uniform lateral load patterns were used to produce a base shear–drift curve. In IDA, seven far-field and seven near-field ground motion records were selected to establish the base shear–drift relationship. Structural response and damage measures were examined by the performance-based seismic design limit states. Vision 2000 proposed four performance states, namely, fully operational, operational, life safety (LS, and near collapse. The results showed that the designed structures have low stiffness because all MRCFs failed to meet the LS limit state. The base shear–drift relationship produced a higher demand in IDA than in POA. In POA, the lateral uniform load pattern produced higher demand than the lateral inverted triangular load pattern. In IDA, the farfield effect produced higher demand than the near-field effect. POA approximated IDA accurately at the elastic stage, but the approximation failed after the yield point.

  9. Is Routine Duodenal Biopsy Necessary for the Detection of Celiac Disease in Patients Presenting with Iron Deficiency Anemia?

    Directory of Open Access Journals (Sweden)

    Mohammad Hassan Emami

    2012-01-01

    Conclusion: CD should be considered in any adult patient presenting with unexplained IDA, even if not accompanied with gastrointestinal symptoms. Routine duodenal biopsy performed during diagnostic upper gastrointestinal endoscopy is worthwhile in order to investigate for CD as an underlying cause of IDA in adult patients.

  10. The dynamic impact on the Central-Eastern European Economies of Accession to the European Union : Social Capability and Technology Absorbtion / David A Dyker

    Index Scriptorium Estoniae

    Dyker, David A

    2001-01-01

    Kesk- ja Ida-Euroopa riikide liitumisest EL-iga ning selle mõjust nende majanduslikule ja infotehnoloogilisele arengule, kaubandusele ja pangandusele. Tabelid: SKT inimese kohta EL-iga liituvates riikides; SKT kasv liituvates riikides 1994-1999; välismaised otseinvesteeringud Ida-Euroopa ja endistesse NL-i riikidesse 1999

  11. International Depository Authority and its Role in Microorganism's Deposition.

    Science.gov (United States)

    Parashar, Abhishek

    2017-08-01

    After the World Trade Organization's agreement on Trade Related Aspect of Intellectual Property Right, patents have come into major play. Patenting of work related to live organisms that have medical, agricultural and other uses is always a tedious, complicated and controversial job. In view of this an agreement called as Budapest Treaty was passed in 1977 for deposition of microorganisms in culture collection centers for patent purpose. To make a culture collection center an IDA the culture center has to follow rules and regulations made in Budapest Treaty. Today several culture collection centers are working as International Depository Authority (IDA) in India and abroad that are storing microorganisms for patent purpose. India has two IDA units; one is Microbial Culture Collection in National Centre for Cell Science Pune, India, and second one is Microbial Type Culture Collection and Gene Bank at Institute of Microbial Technology Chandigarh, India. IDA units are important for valuable sample depositions, supply of cultures, characterization of samples and conservation of biological materials.

  12. Slow hematological recovery in children with IBD-associated anemia in cases of "expectant management".

    Science.gov (United States)

    Pels, Lise P M; Van de Vijver, Els; Waalkens, Herman J; Uitentuis, Jan; JGonera-de ong, Gieneke; van Overbeek, Lidy A T; Norbruis, Obbe F; Rings, Edmond H H M; van Rheenen, Patrick F

    2010-12-01

    Allowing children with inflammatory bowel disease (IBD) to live with subnormal hemoglobin (Hb) levels affects their quality of life. The therapeutic approach to normalize Hb varies according to the cause of IBD-associated anemia. In exclusive iron-deficiency anemia (IDA) repletion of iron stores is obligatory, whereas controlling inflammation is the treatment of choice for anemia of chronic disease (ACD). In daily practice the focus is on control of intestinal inflammation, and spontaneous hematological recovery is awaited. The aim of the present study was to evaluate the hematological effect of "expectant management" on newly diagnosed pediatric patients with IBD with anemia. Medical records of children with IBD were reviewed. Study endpoints were the difference in Hb from the moment of IBD diagnosis (T0) to the end of the induction phase (T1), and time until normalization of Hb, stratified for the type of anemia at T0. A total of 103 children were included in the study, of whom 80 (78%) had anemia at T0. Exclusive IDA was found in 58% of them. Expectant management caused a modest increase in Hb between T0 and T1 for both types of anemia (IDA 0.4 mmol/L; ACD 0.5 mmol/L), but 65 of 80 children (81%) still had anemia at T1. The proportion of children with exclusive IDA had increased to 74%. One third of the cases initially classified as having ACD had progressed to exclusive IDA. There was no significant difference in time until normalization of Hb between children with exclusive IDA and ACD. Twelve months after IBD diagnosis 24% of the group initially diagnosed as having exclusive IDA and 50% of the ACD group were still anemic. Hematological recovery in children with IBD-associated anemia is slow with expectant management, regardless of the type of anemia at T0. Present results underline the need for a more active approach to improve Hb.

  13. Prevalence of Celiac Disease in Patients with Iron Deficiency Anemia - a Systematic Review with Meta-analysis.

    Science.gov (United States)

    Mahadev, Srihari; Laszkowska, Monika; Sundström, Johan; Björkholm, Magnus; Lebwohl, Benjamin; Green, Peter Hr; Ludvigsson, Jonas F

    2018-04-21

    Anemia is common in patients with celiac disease and a frequent presentation. Guidelines recommend screening iron-deficient patients with anemia for celiac disease. However, the reported prevalence of celiac disease among patients with iron-deficiency anemia (IDA) varies. We performed a systematic review to determine the prevalence of biopsy-verified celiac disease in patients with IDA. We performed a systematic review of manuscripts published in PubMed Medline or EMBASE through July 2017 for the term celiac disease combined with anemia or iron-deficiency. We used fixed-effects inverse variance-weighted models to measure the pooled prevalence of celiac disease. Meta-regression was used to assess subgroup heterogeneity. We identified 18 studies comprising 2998 patients with IDA for inclusion in our analysis. Studies originated from the United Kingdom, United States, Italy, Turkey, Iran, and Israel. The crude unweighted prevalence of celiac disease was 4.8% (n=143). Using a weighted pooled analysis, we demonstrated a prevalence of biopsy-confirmed celiac disease 3.2% (95% CI, 2.6%-3.9%) in patients with IDA. However, heterogeneity was high (I 2 = 67.7%). The prevalence of celiac disease was not significantly higher in studies with a mean participant age older or younger than years, nor in studies with a mixed-sex vs female-predominant (≥60%) population. On meta-regression, year of publication, the proportion of females, age at celiac disease testing, and the prevalence of in the general population were not associated with the prevalence of celiac disease in patients with IDA. In the 8 studies fulfilling all our quality criteria, the pooled prevalence of celiac disease was 5.5% (95% CI, 4.1%-6.9%). In a systematic review and meta-analysis, we found that approximately 1 in 31 patients with IDA have histologic evidence of celiac disease. This prevalence value justifies the practice of testing patients with IDA for celiac disease. Copyright © 2018 AGA Institute

  14. CTC Sentinel. Volume 9, Issue 5, May 2016

    Science.gov (United States)

    2016-05-01

    funds through microfinance techniques within the European Union and transferring the proceeds to the Islamic State. With the very recent death of...presence on the al-Qa`ida-affiliated Ansar al-Mujahideen English language forum and other similar al-Qa`ida-linked jihadist forums like Qital Tube and

  15. In vitro antileukemic effect of a new anthracycline analogue, MEN 11079

    DEFF Research Database (Denmark)

    Biscardi, Monica; Caporale, Roberto; Pagliai, Gabriella

    2003-01-01

    the DOXO and IDA ones. MDR (Pgp and MRP1 proteins), as measured by semiquantitative RT-PCR, cytofluorimetric and functional analysis of proteins, was similarly elicited by IDA and MEN 11079. In conclusion, the response of the cells to the new anthracycline indicates that there is greater cytotoxic activity...

  16. Eestlanna, jaapanlanna ja tantsivad kehad / Keiu Virro

    Index Scriptorium Estoniae

    Virro, Keiu, 1987-

    2010-01-01

    Koreograafid-tantsijad Külli Roosna ja Anna esitavad Tallinnas Kanuti Gildi saalis ja Tartus Genialistide klubis oma soolo-tantsuetenduse, milles ühinevad Ida ja Lääs. Läänt esindab Külli Roosna (Eesti) "Circle Through" ja Ida esindab Anna (Jaapan) "Busu". Organisaatoriks on Sõltumatu Tantsu Ühendus

  17. 32 CFR 293.4 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... granted authority to review the decision of the initial denial authority (IDA) (see IDA definition) that... that are part of the decision-making process, and contain subjective evaluations, opinions, and recommendations. A document must be both deliberative and part of a decision-making process to qualify for this...

  18. Acceptance and Effect of Ferrous Fumarate Containing Micronutrient Sprinkles on Anemia, Iron Deficiency and Anthropometrics in Honduran Children

    Science.gov (United States)

    2012-02-01

    problems in infants with IDA at 9 months and concluded that these cognitive effects were partially due to IDA related deficits in socioemotional function...Loechl CU, Menon P, Arimond M, Ruel MT, Pelto G, Habicht JP, Michaud L. (2009). Using programme theory to assess the feasibility of delivering

  19. Advantages of Integrative Data Analysis for Developmental Research

    Science.gov (United States)

    Bainter, Sierra A.; Curran, Patrick J.

    2015-01-01

    Amid recent progress in cognitive development research, high-quality data resources are accumulating, and data sharing and secondary data analysis are becoming increasingly valuable tools. Integrative data analysis (IDA) is an exciting analytical framework that can enhance secondary data analysis in powerful ways. IDA pools item-level data across…

  20. ASSOCIATION OF POTENTIAL CELIAC DISEASE AND REFRACTORY IRON DEFICIENCY ANEMIA IN CHILDREN AND ADOLESCENTS.

    Science.gov (United States)

    Shahriari, Mahdi; Honar, Naser; Yousefi, Ali; Javaherizadeh, Hazhir

    2018-01-01

    Celiac disease is an enteropathy caused by dietary gluten. The combination of serologic, genetic and histologic data has led to description of other categories of this disease. There are a number of patients with iron deficiency anemia (IDA) that do not respond to iron treatment and may be repeated for many times, Therefore, we aimed to investigate celiac disease in this group. In this cross sectional transverse prospective study from August 2011 to February 2013, in a Pediatric care clinic affiliated to Shiraz University of Medical Sciences, 184 children including 92 IDA patients who responded to treatment using iron supplement, 45 non-responding iron deficient patients, and 47 healthy individuals, with the maximum age of 18 years, with written consent from their parents, participated in serologic screening (with Anti-TTG antibody and anti-Endomysial antibody) for celiac disease. Patients with at least one positive serology test underwent multiple mucosal biopsy from bulb and duodenum. Among 184 participants, 19 (10.3%) subjects had positive serologic test for celiac disease, including 13 (28.9%) patients in the group with refractory IDA, 5 (5.4%) patients in the group with treated IDA, and 1 patient in the healthy group. The frequency of positive serologic test in the group with IDA resistant to treatment was prominently higher than the other two groups (Pceliac test who underwent endoscopy and biopsy, no histologic evidence of celiac disease was seen. They were diagnosed as potential celiac disease. Frequency of potential celiac disease in patients with refractory IDA was higher than control the subjects. Therefore, we recommend serologic screening for early detection and minimizing the complications of celiac disease and repeated iron therapy for this group.

  1. Estimating the burden of disease attributable to iron deficiency ...

    African Journals Online (AJOL)

    Objectives. To estimate the extent of iron deficiency anaemia (IDA) among children aged 0 - 4 years and pregnant women aged 15 - 49 years, and the burden of disease attributed to IDA in South Africa in 2000. Design. The comparative risk assessment (CRA) methodology of the World Health Organization (WHO) was ...

  2. Helicobacter pylori Infection and Anemia in Taiwanese Adults

    Directory of Open Access Journals (Sweden)

    Hsiang-Yao Shih

    2013-01-01

    Full Text Available Background. Chronic Helicobacter pylori infection and iron-deficiency anemia (IDA are common in adults. Although the most common causes of IDA usually arise from the gastrointestinal tract, the association between chronic Helicobacter pylori infection and anemia remains unclear. Aim. To evaluate the association of chronic Helicobacter pylori infection and IDA. Materials and Methods. We enrolled 882 patients from January 2010 to April 2013. The status of Helicobacter pylori (H.p infection was confirmed and blood samples from the same participants were taken on the same day to check the level of hemoglobin, serum iron, ferritin, and total iron-binding capacity (TIBC. Results. No significant difference was noted from the demographic data. The average level of hemoglobin (Hb was not different between negative and positive groups, pos 13.57 g/dL versus neg 13.65 g/dL (P=0.699. Although the levels of serum IDA related parameters were expected in positive group (lower serum iron and ferritin and higher TIBC these differences did not reach statistical significance (P=0.824 for iron, P=0.360 for ferritin, and P=0.252 for TIBC. Conclusion. Chronic Helicobacter pylori infection is not attributed to IDA. The levels of hemoglobin, serum iron and ferritin, and TIBC remain unaffected after chronic H.p infection. Large-scale clinical studies are needed to prove the association.

  3. Erakonnad kombineerivad valimisnimekirju / Erik Gamzejev

    Index Scriptorium Estoniae

    Gamzejev, Erik, 1967-

    2006-01-01

    Ilmunud ka: Severnoje Poberezhje 5. okt. lk. 1,3. Suuremad erakonnad on praeguseks Ida-Virus suuremalt jaolt välja valinud kandidaadid, kes hakkavad parlamendivalimistel hääli koguma. Tabelid: Häälte jagunemine erakondadel vahel 2003. aasta riigikogu valimistel; Suuremad häältekogujad Ida-Virus 2003. a. riigikogu valimistel

  4. Effects of Vitamin A Supplementation on Iron Status Indices and Iron Deficiency Anaemia: A Randomized Controlled Trial

    Directory of Open Access Journals (Sweden)

    Hesham M. Al-Mekhlafi

    2013-12-01

    Full Text Available Iron deficiency anaemia (IDA is the most common nutritional deficiency in the world including developed and developing countries. Despite intensive efforts to improve the quality of life of rural and aboriginal communities in Malaysia, anaemia and IDA are still major public health problems in these communities particularly among children. A randomized, double-blind, placebo-controlled trial was conducted on 250 Orang Asli (aboriginal schoolchildren in Malaysia to investigate the effects of a single high-dose of vitamin A supplementation (200,000 IU on iron status indices, anaemia and IDA status. The effect of the supplement was assessed after 3 months of receiving the supplements; after a complete 3-day deworming course of 400 mg/day of albendazole tablets. The prevalence of anaemia was found to be high: 48.5% (95% CI = 42.3, 54.8. Moreover, 34% (95% CI = 28.3, 40.2 of the children had IDA, which accounted for 70.1% of the anaemic cases. The findings showed that the reduction in serum ferritin level and the increments in haemoglobin, serum iron and transferrin saturation were found to be significant among children allocated to the vitamin A group compared to those allocated to the placebo group (p < 0.01. Moreover, a significant reduction in the prevalence of IDA by almost 22% than prevalence at baseline was reported among children in the vitamin A group compared with only 2.3% reduction among children in the placebo group. In conclusion, vitamin A supplementation showed a significant impact on iron status indices and IDA among Orang Asli children. Hence, providing vitamin A supplementation and imparting the knowledge related to nutritious food should be considered in the efforts to improve the nutritional and health status of these children as a part of efforts to improve the quality of life in rural and aboriginal communities.

  5. Iron deficiency anaemia in pre-school (1- 6 years) in Al Shigla area (Khartoum State) :Prevalence and Aetiology

    International Nuclear Information System (INIS)

    Osman, Faiza Mohamed

    1999-04-01

    iron deficiency anaemia (IDA) is a public health problem throughout the world. Childhood iron deficiency anaemia. A prospective survey (systematic, cluster sampling) was carried out among pre-school children in Alshigla area (Khartoum State), to study the prevalence and aetological factors of IDA. 170 children selected for general nutritional evaluation, 110 of them for haemoglobin levels and morphological classification of anaemia, 70 for further investigations(serum iron, unsaturated iron binding capacity, total iron binding capacity). The population at Alshigla were living in poor condition 85.3% relied on water brought by tankers which showed poor hygienic standard, 90% lived in extended families 54.1% had income level less than LS 3000/day irrespective of family size or mode of spending. A sample of 170 children showed (84.1%) normal nutritional status with 4.7% severe cases with high consumption of cereals low meat, fish and poultry group and vitamin C(22.9%). Disease episodes showed 67.7% had diarrhoea, 22.4% had giardia, 12.9% had malaria and 10.6% had worm infestation. This most probably due to unsanitary living condition. Haemoglobin analysis using Enzyme Linked Immunosorbent assay technique (ELISA) for 110 of the children, showed high prevalence of anaemia (96.4%), 66% prevalence of IDA. Further haematological investigations of 50 of the children confirmed them as IDA cases.Thus the high prevalence of IDA in Alshigla was multi-factorial, inadequate take of dietary iron and of vitamin C, high intake of cereals and legumes, low intake of meat, poultry and fish group (MPF),and high tea consumption, thus food provides inadequate supply of iron and were rich in inhibitors of iron absorption. In addition episodes of diseases that may influence food (hence iron) utilisation contributed to the prevalence of IDA

  6. Mild Maternal Iron Deficiency Anemia Induces Hearing Impairment Associated with Reduction of Ribbon Synapse Density and Dysregulation of VGLUT3, Myosin VIIa, and Prestin Expression in Young Guinea Pigs.

    Science.gov (United States)

    Yu, Fei; Hao, Shuai; Yang, Bo; Zhao, Yue; Zhang, Wenyue; Yang, Jun

    2016-05-01

    Mild maternal iron deficiency anemia (IDA) adversely affects the development of cochlear hair cells of the young offspring, but the mechanisms underlying the association are incompletely understood. The aim of this study was to evaluate whether mild maternal IDA in guinea pigs could interrupt inner hair cell (IHC) ribbon synapse density and outer hair cell motility of the offspring. Here, we established a dietary restriction model that allows us to study quantitative changes in the number of IHC ribbon synapses and hearing impairment in response to mild maternal IDA in young guinea pig. The offspring were weaned on postnatal day (PND) 9 and then were given the iron-sufficient diet. On PND 24, pups were examined the hearing function by auditory brainstem response (ABR) and distortion product otoacoustic emission (DPOAE) measurements. Then, the cochleae were harvested for assessment of the number of IHC ribbon synapses by immunofluorescence, the morphology of cochlear hair cells, and spiral ganglion cells (SGCs) by scanning electron microscope and hematoxylin-eosin staining, the location, and expression of vesicular glutamate transporter (VGLUT) 3, myosin VIIa, and prestin by immunofluorescence and blotting. Here, we show that mild maternal IDA in guinea pigs induced elevated ABR threshold shifts, declined DPOAE level shifts, and reduced the number of ribbon synapses, impaired the morphology of cochlear hair cells and SGCs in offsprings. In addition, downregulation of VGLUT3 and myosin VIIa, and upregulation of prestin were observed in the cochlea of offsprings from mild maternal IDA in guinea pigs. These data indicate that mild maternal IDA in guinea pigs induced hearing impairment in offsprings, and this deficit may be attributed to the reduction of ribbon synapse density and dysregulation of VGLUT3, myosin VIIa, and prestin.

  7. Iron assessment to protect the developing brain.

    Science.gov (United States)

    Georgieff, Michael K

    2017-12-01

    Iron deficiency (ID) before the age of 3 y can lead to long-term neurological deficits despite prompt diagnosis of ID anemia (IDA) by screening of hemoglobin concentrations followed by iron treatment. Furthermore, pre- or nonanemic ID alters neurobehavioral function and is 3 times more common than IDA in toddlers. Given the global prevalence of ID and the enormous societal cost of developmental disabilities across the life span, better methods are needed to detect the risk of inadequate concentrations of iron for brain development (i.e., brain tissue ID) before dysfunction occurs and to monitor its amelioration after diagnosis and treatment. The current screening and treatment strategy for IDA fails to achieve this goal for 3 reasons. First, anemia is the final state in iron depletion. Thus, the developing brain is already iron deficient when IDA is diagnosed owing to the prioritization of available iron to red blood cells over all other tissues during negative iron balance in development. Second, brain ID, independently of IDA, is responsible for long-term neurological deficits. Thus, starting iron treatment after the onset of IDA is less effective than prevention. Multiple studies in humans and animal models show that post hoc treatment strategies do not reliably prevent ID-induced neurological deficits. Third, most currently used indexes of ID are population statistical cutoffs for either hematologic or iron status but are not bioindicators of brain ID and brain dysfunction in children. Furthermore, their relation to brain iron status is not known. To protect the developing brain, there is a need to generate serum measures that index brain dysfunction in the preanemic stage of ID, assess the ability of standard iron indicators to detect ID-induced brain dysfunction, and evaluate the efficacy of early iron treatment in preventing ID-induced brain dysfunction. © 2017 American Society for Nutrition.

  8. Breastfeeding and Red Meat Intake Are Associated with Iron Status in Healthy Korean Weaning-age Infants.

    Science.gov (United States)

    Hong, Jeana; Chang, Ju Young; Shin, Sue; Oh, Sohee

    2017-06-01

    The present study investigated risk factors for iron deficiency (ID) and iron deficiency anemia (IDA) during late infancy, including feeding type and complementary feeding (CF) practice. Healthy term Korean infants (8-15 months) were weighed, and questionnaires regarding delivery, feeding, and weaning were completed by their caregivers. We also examined levels of hemoglobin, serum iron/total iron-binding capacity, serum ferritin, and mean corpuscular volume (MCV). Among 619 infants, ID and IDA were present in 174 infants (28.1%) and 87 infants (14.0%), respectively. The 288 infants with exclusively/mostly breastfeeding until late infancy (BFL) were most likely to exhibit ID (53.1%) and IDA (28.1%). The risk of ID was independently associated with BFL (adjusted odds ratio [aOR], 47.5; 95% confidence interval [CI], 18.3-122.9), male sex (aOR, 1.9; 95% CI, 1.2-2.9), fold weight gain (aOR, 2.6; 95% CI, 1.5-4.6), and perceived inadequacy of red meat intake (aOR, 1.7; 95% CI, 1.0-2.7). In addition to the risk factors for ID, Cesarean section delivery (aOR, 1.9; 95% CI, 1.1-3.2) and low parental CF-related knowledge (aOR, 2.8; 95% CI, 1.5-5.2) were risk factors for IDA. In conclusion, prolonged breastfeeding and perceived inadequacy of red meat intake may be among the important feeding-related risk factors of ID and IDA. Therefore, more meticulous education and monitoring of iron-rich food intake, such as red meat, with iron supplementation or iron status testing during late infancy if necessary, should be considered for breastfed Korean infants, especially for those with additional risk factors for ID or IDA. © 2017 The Korean Academy of Medical Sciences.

  9. Effect of iron deficiency anemia and iron supplementation on HbA1c levels - Implications for diagnosis of prediabetes and diabetes mellitus in Asian Indians.

    Science.gov (United States)

    Madhu, S V; Raj, Abhishek; Gupta, Stuti; Giri, S; Rusia, Usha

    2017-05-01

    We investigated the effect of iron deficiency anemia (IDA) on levels of glycated hemoglobin (HbA1c) and to compare its levels before and after iron supplementations. Age and sex matched subjects were enrolled and clustered in 2 groups: IDA (n=62) and healthy controls (HC; n=60). HbA1c levels were estimated by HPLC. Hemogram were estimated by hematology analyser. Serum ferritin (ELISA) and other parameters of iron profile were measured by standard guidelines of ICSH. HbA1c values and iron studies were repeated after 3months of iron supplementation to determine the effect of iron therapy on HbA1c levels. Significantly higher HbA1c levels were observed in IDA subjects compared to HC (5.51±0.696 v/s 4.85±0.461%, pHbA1c and hemoglobin, hematocrit, RBC count, MCH, MCHC and serum ferritin in IDA subjects (r=-0.632, -0.652, -0.384, -0.236, -0.192 and -0.441). Significant decline was noticed in HbA1c levels in IDA subjects after iron supplementation (5.51±0.696 before treatment v/s 5.044±0.603 post-treatment; pHbA1c in pre-diabetes range normalised to normal glucose tolerance (NGT) range and out of 6 patients with pre-treatment HbA1c in diabetes range, 5 reverted to pre-diabetes range while 1 of them reverted to the NGT range. Caution must be exercised in interpreting the results of HbA1c in patients of IDA and iron deficiency must be corrected before diagnosing diabetes and pre-diabetes solely on the basis of HbA1c criteria. Copyright © 2016. Published by Elsevier B.V.

  10. The effects of iron deficiency and anaemia on primary school ...

    African Journals Online (AJOL)

    the age of 5 years do not reach their developmental potential.[1,2]. ID and ID anaemia (IDA) are widespread health problems among children. Approximately 40% of ..... withdraw at any time without providing a reason, or it affecting their schooling. ... also included in the cases, leaving 45 cases (23.2%) of mild non-. IDA.

  11. St. Ola sõitis Virumaa lipulaevana Soome / Gerli Romanovitsh

    Index Scriptorium Estoniae

    Romanovitš, Gerli, 1977-

    2005-01-01

    Ilmunud ka: Severnoje Poberezhje 10. juuni lk 1,4. Parvlaev St. Ola alustas sõitu Sillamäelt Kotkasse, et viia Ida-Virumaa esindajad Kouvolas toimuvale messile, millest poole võtab enda alla Virumaa väljapanek. Järgmisel aastal käivitub Sillamäe-Kotka regulaarlaevaliin. Ida-Viru maavanema Ago Silde kommentaar

  12. Kiwa Frankfurdis : great big fuck!

    Index Scriptorium Estoniae

    1999-01-01

    Frankfurdis 20.-21. XI toimunud kongressil Ida-Euroopa kunstist näitas kuraator Dmitry Vilensky enne oma ettekannet "Sõnum idast" Kiwa videot "Euro-Antivisioon. Kollase lipu all". D. Vilensky korraldatud illegaalsel posterite "näitusel" plankudel, kus Ida-Euroopa kunstnikud said avaldada arvamust Lääne kunstiinstitutsioonide strateegiate kohta, osalesid Aleksandr Brener, Oleg Kulik

  13. Iron Deficiency Anemia in Relation to Respiratory Disease and Social Behaviors In Low-Income Infants in France.

    Science.gov (United States)

    Honig, Alice Sterling

    1993-01-01

    Examined a sample of 177 infants (age 9 through 12 months) with iron deficiency anemia (IDA) from low-income French, African, and North African Muslim families in Paris. Found a higher than normal incidence of otitis media and respiratory diseases such as bronchitis among the infants. Also examined the relationship between infant IDA and child…

  14. Radiation absorption of newborns at cholescintigraphy

    International Nuclear Information System (INIS)

    Hahn, K.; Lingenfelder, B.; Wolf, R.; Eissner, D.

    1982-01-01

    The cholescintigraphy with 99m Tc-IDA has become essential to diagnose the presence of biliary atresia early in its clinical course. With this wider clinical application it is essential to have data about the radiation dose of these substances. While the radiation dose of 99m Tc-IDA has been calculated for adults there are in the literature no radiation dose calculations for newborns and young children. In this work the cumulated activity of 99m Tc-diaethyl-IDA in the organs of young pigs was measured 15, 30, 45 and 60 min. and 24 hours after injection of the radiopharmaceutical. The radiation dose calculation for newborns and youngchildren was performed on these animal biokinetic data using a biological approach including the absorbed-fraction concept. The results show that the radiation dose absorbed by the gonads as well as by the critical organs (thyroid, gallbladder, liver, upper and lower large intestine) are significantlyl lower than those of the cholescintigraphy with J-131 rose bengal. Therefore 99m Tc-IDA can be safely applied to newborns and young children. (Author)

  15. What Is the Real Public Health Significance of Iron Deficiency and Iron Deficiency Anaemia in Croatia? A Population-Based Observational Study on Pregnant Women at Early Pregnancy from Eastern Croatia.

    Science.gov (United States)

    Banjari, Ines; Kenjerić, Daniela; Mandić, Milena L

    2015-06-01

    Studies imply that significance of iron deficiency (ID) and iron deficiency anaemia (IDA) for pregnancy outcomes is especially highlighted in the early pregnancy. Prevalence around the world varies widely, however, no data is available up to date for Croatia or neighbouring countries. Therefore, the objective was to determine the prevalence of ID and IDA among pregnant women from Croatia at the first trimester. Also, the aim was to compare two criterions; the World Health Organization (WHO) one and the clinical one. Randomised observational population based study was set up and 265 pregnant women at the first trimester were enrolled. Based on the WHO criteria, 17.7% on haemoglobin basis and 18.5% on haematocrit basis had either ID or IDA. Clinical criteria showed that even 32.8% had either ID or IDA (transferrin saturation pregnancy as iron deficient, presents a potentially high risk for the pregnancy outcomes, especially in terms of a newborn, and it is fully justified to treat them as diseases of public health significance. Copyright© by the National Institute of Public Health, Prague 2015.

  16. International dose assurance service programme of the International Atomic Energy Agency

    International Nuclear Information System (INIS)

    Nam, J.W.

    1988-01-01

    In order to execute normalization of high-doses on an international scale and to further promote dosimetry as quality control measures in radiation processing, the International Dose Assurance Service (IDAS) has recently been initiated in the framework of a high-dose standardization programme. IDAS is being provided on the basis of an ''Agreement Concerning the Provision of a Dose Assurance Service by the IAEA to Irradiation Facilities in its Member States''. The aim of the IDAS programme will be to meet stringent requirements for standardization of dosimetry, and to achieve concerted international efforts for quality assurance of radiation processing. Details of the programme and the achievements made to date are discussed. (author). 5 refs

  17. Party competition structure in Eastern Europe: aggregate uniformity versus idiosyncratic diversity? / Jan Rovny

    Index Scriptorium Estoniae

    Rovny, Jan

    2015-01-01

    Artiklis analüüsitakse parteide võitlust võimu ja rahva esindamise pärast Ida-Euroopa riikides (s.h. Eesti). Esitatakse tegureid ja seoseid, mis määratlevad parteide konkurentsi regioonis, tutvustatakse nn. hääle valiku mudelt, millega testitakse kümne Ida-Euroopa riigi andmeid 2009. aasta Euroopa valimiste uuringust

  18. UXO Burial Prediction Fidelity: A Summary

    Science.gov (United States)

    2017-07-01

    A-1 1 Introduction The Institute for Defense Analyses (IDA) is a not-for-profit company that...collection of information, including suggestions for reducing the burden, to Department of Defense, Washington Headquarters Services, Directorate for...November 2017). 13. SUPPLEMENTARY NOTES 14. ABSTRACT The Institute for Defense Analyses (IDA) is a not-for-profit company that operates three Federal

  19. 32 CFR 286.23 - Initial determinations.

    Science.gov (United States)

    2010-07-01

    ... number of IDAs appointed. In designating its IDAs, a DoD Component shall balance the goals of... tests. To deny a requested record that is in the possession and control of a DoD Component, it must be....S. government source. (1) When a request is received for a record that falls under exemption 4 (see...

  20. 'Den danske model' som tema

    DEFF Research Database (Denmark)

    Caraker, Emmett; Juul, Ida; Klindt, Mads Peter

    2012-01-01

    Tidsskrift for Arbejdsliv vol. 14, nr. 2, 5-8. Tema: 'Den danske model'. Redigeret af Emmett Caraker, Ida Juul, Mads peter Klindt & Jens Lind. 2011. København. 128 s.......Tidsskrift for Arbejdsliv vol. 14, nr. 2, 5-8. Tema: 'Den danske model'. Redigeret af Emmett Caraker, Ida Juul, Mads peter Klindt & Jens Lind. 2011. København. 128 s....

  1. Nutritional iron deficiency anemia: magnitude and its predictors among school age children, southwest Ethiopia: a community based cross-sectional study.

    Science.gov (United States)

    Desalegn, Amare; Mossie, Andualem; Gedefaw, Lealem

    2014-01-01

    Iron deficiency anemia (IDA) is a global public health problem among school age children, which retards psychomotor development and impairs cognitive performance. There is limited data on prevalence and risk factors for IDA. The aim of this study was to determine the prevalence, severity, and predictors of nutritional IDA in school age children in Southwest Ethiopia. A community based cross-sectional study was conducted in Jimma Town, Southwest Ethiopia from April to July 2013. A total of 616 school children aged 6 to 12 years were included in the study using multistage sampling technique. A structured questionnaire was used to collect sociodemographic data. Five milliliter venous blood was collected from each child for hematological examinations. Anemia was defined as a hemoglobin level lower than 11.5 g/dl and 12 g/dl for age group of 5-11 years and 12-15 years, respectively. Iron deficiency anemia was defined when serum iron and ferritin levels are below 10 µmol/l and 15 µg/dl, respectively. Moreover, fresh stool specimen was collected for diagnosis of intestinal parasitic infection. Stained thick and thin blood films were examined for detection of Plasmodium infection and study of red blood cell morphology. Dietary patterns of the study subjects were assessed using food frequency questionnaire and anthropometric measurements were done. Data were analyzed using SPSS V-20.0 for windows. Overall, prevalence of anemia was 43.7%, and that of IDA was 37.4%. Not-consuming protein source foods [AOR = 2.30, 95%CI(1.04,5.14)], not-consuming dairy products [AOR = 1.83, 95%CI(1.14,5.14)], not-consuming discretionary calories [AOR = 2.77, 95%CI(1.42,5.40)], low family income [AOR = 6.14, 95%CI(2.90,12.9)] and intestinal parasitic infections [AOR = 1.45, 95%CI(1.23, 5. 27)] were predictors of IDA. Iron deficiency anemia is a moderate public health problem in the study site. Dietary deficiencies and intestinal parasitic infections were predictors of IDA

  2. Nutritional iron deficiency anemia: magnitude and its predictors among school age children, southwest Ethiopia: a community based cross-sectional study.

    Directory of Open Access Journals (Sweden)

    Amare Desalegn

    Full Text Available Iron deficiency anemia (IDA is a global public health problem among school age children, which retards psychomotor development and impairs cognitive performance. There is limited data on prevalence and risk factors for IDA.The aim of this study was to determine the prevalence, severity, and predictors of nutritional IDA in school age children in Southwest Ethiopia.A community based cross-sectional study was conducted in Jimma Town, Southwest Ethiopia from April to July 2013. A total of 616 school children aged 6 to 12 years were included in the study using multistage sampling technique. A structured questionnaire was used to collect sociodemographic data. Five milliliter venous blood was collected from each child for hematological examinations. Anemia was defined as a hemoglobin level lower than 11.5 g/dl and 12 g/dl for age group of 5-11 years and 12-15 years, respectively. Iron deficiency anemia was defined when serum iron and ferritin levels are below 10 µmol/l and 15 µg/dl, respectively. Moreover, fresh stool specimen was collected for diagnosis of intestinal parasitic infection. Stained thick and thin blood films were examined for detection of Plasmodium infection and study of red blood cell morphology. Dietary patterns of the study subjects were assessed using food frequency questionnaire and anthropometric measurements were done. Data were analyzed using SPSS V-20.0 for windows.Overall, prevalence of anemia was 43.7%, and that of IDA was 37.4%. Not-consuming protein source foods [AOR = 2.30, 95%CI(1.04,5.14], not-consuming dairy products [AOR = 1.83, 95%CI(1.14,5.14], not-consuming discretionary calories [AOR = 2.77, 95%CI(1.42,5.40], low family income [AOR = 6.14, 95%CI(2.90,12.9] and intestinal parasitic infections [AOR = 1.45, 95%CI(1.23, 5. 27] were predictors of IDA.Iron deficiency anemia is a moderate public health problem in the study site. Dietary deficiencies and intestinal parasitic infections were

  3. Ida-Euroopa kunst Londonis

    Index Scriptorium Estoniae

    2011-01-01

    Eve Kase kureeritud näitus "Memoirs from a Cold Utopia" Londonis 28. juulist 28. novembrini 2011. Näitus tähistab Nõukogude Liidu lagunemise 20. aastapäeva. Eestist osalevad Marko Mäetamm, Anu Juurak, Tanja Muravskaja

  4. Instant Data Analysis (IDA)

    DEFF Research Database (Denmark)

    Stage, Jan; Kjeldskov, Jesper; Skov, Morten Krogh

    2007-01-01

    rd Open Workshop: Review, Report and Refine Usability Evaluation Methods (R3 UEMs) The COST294-MAUSE working group has undertaken the challenge to develop an approach to critically reviewing and analyzing Usability Evaluation Methods. The aim of this workshop is to build a knowledge-pool around t...

  5. Iron-deficiency anemia in infancy and social emotional development in preschool-aged Chinese children.

    Science.gov (United States)

    Chang, Suying; Wang, Li; Wang, Yuying; Brouwer, Inge D; Kok, Frans J; Lozoff, Betsy; Chen, Chunming

    2011-04-01

    We aimed to compare affect and behavior of 3 groups of nonanemic 4-year-old children: children with iron-deficiency anemia (IDA) in infancy whose anemia was not corrected before 24 months (chronic IDA) (n = 27); children with IDA in infancy whose anemia was corrected before 24 months (corrected IDA) (n = 70); and children who were nonanemic in infancy and at 24 months (n = 64). Mother and child dyads were invited to a local clinic room. Children's social referencing, wariness, frustration-tolerance behavior, and affect were observed during a set of situations encountered in the laboratory, including free play, stranger approach, novel toy, and delay of gratification. The whole procedure was videotaped. The children's affective and behavioral displays were coded by using a time-sampling (5-second segments) code scheme. Iron status of children was determined on the basis of hemoglobin concentration measured with the cyanomethemoglobin method in blood samples obtained by fingerstick in infancy and at the ages of 24 months and 4 years. Children who had chronic IDA in infancy displayed less positive affect, less frustration tolerance, more passive behavior, and more physical self-soothing in the stranger approach and delay of gratification. In contrast, the behavior and affect of children whose anemia was corrected before the age of 24 months were comparable to those of children who were nonanemic throughout infancy. The results point to the potential benefits of preventing iron deficiency in infancy and treating it before it becomes chronic or severe.

  6. Lotte lasteaed : Ida 8, Tartu = Lotte Nursery School : Ida 8, Tartu / Margit Mutso

    Index Scriptorium Estoniae

    Mutso, Margit, 1966-

    2009-01-01

    Lasteaiast, mille arhitektid on Indrek Peil ja Siiri Vallner (pälvisid riigi kultuuripreemia, Kavakava), sisearhitektid Tea Tammelaan, Malle Jürgenson, Krista Lepland (pälvisid EK arhitektuuri sihtkapitali aastapreemia 2008) ja Sirli Ehari (Laika, Belka & Strelka), maastikuarhitekt Anna-Liisa Unt. Žürii hinnang lasteaiale

  7. Bonzo tuuritab kirikutes

    Index Scriptorium Estoniae

    2007-01-01

    Laulja Bonzo ja Ahti Bachblumi kirikukontserdituurist kavaga "Mees ja Jumal" 29. juulil Haljalas, 30. juulil Harjumaal Leesis, 31. juulil Käsmus, 1. aug. Vainupeal, 2. aug. Ida-Virumaal Lüganusel, 3. aug. Hiiumaal Pühalepas, 5. aug. Harjumaal Rannamõisas ja 6. aug. Ida-Virumaal Pühajõel. Bonzol koos ansambliga Jäääär kontsert ka 5. aug. Kohilas

  8. Dietary Composition Influences Incidence of Helicobacter pylori-Induced Iron Deficiency Anemia and Gastric Ulceration

    Science.gov (United States)

    Beckett, Amber C.; Piazuelo, M. Blanca; Noto, Jennifer M.; Peek, Richard M.; Washington, M. Kay; Algood, Holly M. Scott

    2016-01-01

    Epidemiologic studies have provided conflicting data regarding an association between Helicobacter pylori infection and iron deficiency anemia (IDA) in humans. Here, a Mongolian gerbil model was used to investigate a potential role of H. pylori infection, as well as a possible role of diet, in H. pylori-associated IDA. Mongolian gerbils (either H. pylori infected or uninfected) received a normal diet or one of three diets associated with increased H. pylori virulence: high-salt, low-iron, or a combination of a high-salt and low-iron diet. In an analysis of all infected animals compared to uninfected animals (independent of diet), H. pylori-infected gerbils had significantly lower hemoglobin values than their uninfected counterparts at 16 weeks postinfection (P Anemia was associated with the presence of gastric ulceration but not gastric cancer. Infected gerbils consuming diets with a high salt content developed gastric ulcers significantly more frequently than gerbils consuming a normal-salt diet, and the lowest hemoglobin levels were in infected gerbils consuming a high-salt/low-iron diet. These data indicate that H. pylori infection can cause IDA and that the composition of the diet influences the incidence and severity of H. pylori-induced IDA. PMID:27620719

  9. Learning for design reuse

    DEFF Research Database (Denmark)

    Duffy, Alex; Duffy, Sandra M.

    1996-01-01

    Over the past decade "design assistance", that is, where the computer is viewed as an Intelligent Design Assistant (IDA), has emerged in knowledge based design support and has formed the basic research strategy for the CAD Cantre, University of Strathclyde, since the mid-1980s. Within this philos......Over the past decade "design assistance", that is, where the computer is viewed as an Intelligent Design Assistant (IDA), has emerged in knowledge based design support and has formed the basic research strategy for the CAD Cantre, University of Strathclyde, since the mid-1980s. Within...... this philosophy, an IDA would act as a colleague to a designer, providing guidance, learning from past experiences, carrying out semi- and fully-automated tasks, explaining its reasoning and in essence complementing the designer's own natural skills, and thus leaving the ultimate decision-making, control......, and responsibility with the designer.The ability to learn and evolve has been recognized as one of the key components of an IDA for it to fully support the designer's activities. Consequently, we have been directing our research effort on two main fronts, formalizing our understanding and developing models...

  10. A Decision-Analytic Feasibility Study of Upgrading Machinery at a Tools Workshop

    Directory of Open Access Journals (Sweden)

    M. L. Chew Hernandez

    2012-04-01

    Full Text Available This paper presents the evaluation, from a Decision Analysis point of view, of the feasibility of upgrading machinery at an existing metal-forming workshop. The Integral Decision Analysis (IDA methodology is applied to clarify the decision and develop a decision model. One of the key advantages of the IDA is its careful selection of the problem frame, allowing a correct problem definition. While following most of the original IDA methodology, an addition to this methodology is proposed in this work, that of using the strategic Means-Ends Objective Network as a backbone for the development of the decision model. The constructed decision model uses influence diagrams to include factual operator and vendor expertise, simulation to evaluate the alternatives and a utility function to take into account the risk attitude of the decision maker. Three alternatives are considered: Base (no modification, CNC (installing an automatic lathe and CF (installation of an automatic milling machine. The results are presented as a graph showing zones in which a particular alternative should be selected. The results show the potential of IDA to tackle technical decisions that are otherwise approached without the due care.

  11. A mid-layer model for human reliability analysis: understanding the cognitive causes of human failure events

    International Nuclear Information System (INIS)

    Shen, Song-Hua; Chang, James Y.H.; Boring, Ronald L.; Whaley, April M.; Lois, Erasmia; Langfitt Hendrickson, Stacey M.; Oxstrand, Johanna H.; Forester, John Alan; Kelly, Dana L.; Mosleh, Ali

    2010-01-01

    The Office of Nuclear Regulatory Research (RES) at the US Nuclear Regulatory Commission (USNRC) is sponsoring work in response to a Staff Requirements Memorandum (SRM) directing an effort to establish a single human reliability analysis (HRA) method for the agency or guidance for the use of multiple methods. As part of this effort an attempt to develop a comprehensive HRA qualitative approach is being pursued. This paper presents a draft of the method's middle layer, a part of the qualitative analysis phase that links failure mechanisms to performance shaping factors. Starting with a Crew Response Tree (CRT) that has identified human failure events, analysts identify potential failure mechanisms using the mid-layer model. The mid-layer model presented in this paper traces the identification of the failure mechanisms using the Information-Diagnosis/Decision-Action (IDA) model and cognitive models from the psychological literature. Each failure mechanism is grouped according to a phase of IDA. Under each phase of IDA, the cognitive models help identify the relevant performance shaping factors for the failure mechanism. The use of IDA and cognitive models can be traced through fault trees, which provide a detailed complement to the CRT.

  12. Iron deficiency anemia interfering the diagnosis of compound heterozygosity for Hb constant spring and Hb Paksé: The first case report.

    Science.gov (United States)

    Chiasakul, Thita; Uaprasert, Noppacharn

    2018-01-01

    Diagnosis of thalassemia or hemoglobinopathy concomitant with iron deficiency anemia (IDA) is challenging. We report a case of 43-year-old female whose diagnosis of compound heterozygosity for hemoglobin Constant Spring (HbCS) and Hb Paksé became apparent after the treatment of IDA. Prior to treatment, Hb analysis using isoelectric focusing (IEF) showed HbA 95.6%, HbA 2 2.7%, and HbCS 1.7% compatible with heterozygous HbCS. After 4 months of oral iron therapy resulting in an improved Hb level, her HbCS level was substantially increased to 8.7% on IEF suggesting homozygous HbCS. Subsequent DNA analysis using multiplex amplification refractory mutation system analysis revealed compound heterozygosity for HbCS and Hb Paksé. This case demonstrated that IDA can significantly reduce HbCS/Hb Paksé levels and probably mask the diagnosis of homozygous HbCS, homozygous Hb Paksé or the compound heterozygosity for both hemoglobinopathies by hemoblogin analysis. The test should be repeated after resolution of IDA, or molecular testing should be performed to confirm the diagnosis. © 2017 Wiley Periodicals, Inc.

  13. Correlation between iron deficiency anemia and intestinal parasitic infection in school-age children in Medan

    Science.gov (United States)

    Darlan, D. M.; Ananda, F. R.; Sari, M. I.; Arrasyid, N. K.; Sari, D. I.

    2018-03-01

    Anemia is an abnormal hemoglobin concentration in blood that impacts almost 40% school-age children in developing countries. Intestinal parasitic infection, along with malnutrition are contributed to influence absorption, transportation, and metabolism of iron which is the most common etiology of anemia in school-age children. The purpose of this study was to determine whether there is a correlation between iron deficiency anemia (IDA) and parasitic intestinal infection generally and protozoa infection particularly among school-age children in Medan. This was a cross-sectional study conducted from May until October 2016 in primaryschool in Medan and Hamparan Perak, Deli Serdang. Consecutive sampling was used with total 132 samples obtained. Univariate analysis and Bivariate analysis were performed.This study showed the prevalence of IDA was 7.6%, and proportion of parasitic intestinal infection was 26.5% with 19.8% protozoa infection. The correlation between IDA and intestinal parasitic infection was not significant in Chi-Square Test (p-value: 0.089), neither was between IDA and protozoa infection (p-value: 0.287). There was a correlation between MCV, MCH, and anemia with p-valueanemia, parasitic infection, and protozoa infection (p-value>0.05).

  14. A Mid-Layer Model for Human Reliability Analysis: Understanding the Cognitive Causes of Human Failure Events

    Energy Technology Data Exchange (ETDEWEB)

    Stacey M. L. Hendrickson; April M. Whaley; Ronald L. Boring; James Y. H. Chang; Song-Hua Shen; Ali Mosleh; Johanna H. Oxstrand; John A. Forester; Dana L. Kelly; Erasmia L. Lois

    2010-06-01

    The Office of Nuclear Regulatory Research (RES) is sponsoring work in response to a Staff Requirements Memorandum (SRM) directing an effort to establish a single human reliability analysis (HRA) method for the agency or guidance for the use of multiple methods. As part of this effort an attempt to develop a comprehensive HRA qualitative approach is being pursued. This paper presents a draft of the method’s middle layer, a part of the qualitative analysis phase that links failure mechanisms to performance shaping factors. Starting with a Crew Response Tree (CRT) that has identified human failure events, analysts identify potential failure mechanisms using the mid-layer model. The mid-layer model presented in this paper traces the identification of the failure mechanisms using the Information-Diagnosis/Decision-Action (IDA) model and cognitive models from the psychological literature. Each failure mechanism is grouped according to a phase of IDA. Under each phase of IDA, the cognitive models help identify the relevant performance shaping factors for the failure mechanism. The use of IDA and cognitive models can be traced through fault trees, which provide a detailed complement to the CRT.

  15. MO-F-CAMPUS-I-05: Radiation Dosimetry of 99mTc-IDA-D-[c(RGDfK)]2, a SPECT Agent for Angiogenesis Imaging

    Energy Technology Data Exchange (ETDEWEB)

    Kim, J [Korea Research Institute of Standards and Science, Daejeon (Korea, Republic of)

    2015-06-15

    Purpose: Tc-99m labeled IDA-D-[c(RGDfK){sub 2} ( {sup 99m}Tc-RGD) is a recently developed radiotracer for gamma camera or single photon emission computed tomography (SPECT) imaging and promising agent for the visualization of angiogenesis. In this study, we investigated the internal radiation dosimetry of {sup 99m}Tc-RGD in humans. Methods: Six normal controls (F:M=4:2; 68.3±3.2 years; 56.5±10.7 kg) were participated in this study. Simultaneous anterior and posterior scans of whole-body were performed using dual head gamma camera system. Before the emission scan, transmission scan was performed just before injection of {sup 99m}Tc-RGD using Co-57 flood source. After an intravenous injection of 388.7±29.3 MBq of {sup 99m}Tc-RGD, six serial emission scans were performed at 0, 1, 2, 4, 8 and 24 hours post-injection. The anterior and posterior images were geometrically averaged and attenuation correction was applied using transmission scan image. Regions of interest (ROIs) were drawn on liver, gallbladder, kidneys, urinary bladder, spleen, brain, and large intestine. Time activity curves were obtained from serial emission scan and ROIs. The number of disintegrations per unit activity administered (residence time) were calculated from the area under the curve of time activity curves and injected dose of each patient. Finally, the radiation dose for each organ and effective doses were obtained using OLINDA/EXM 1.1 software and residence time. Results: High radiation doses were reported on renal and biliary excretion tracks such as urinary bladder wall, upper large intestine, kidneys, liver and gallbladder wall and their doses were 19.15±6.84, 19.28±4.78, 15.67±0.90, 9.13±1.71 and 9.09±2.03 µGy/MBq, respectively. The effective dose and effective dose equivalent were 5.08±0.53 and 7.11±0.58 µSv/MBq, respectively. Conclusion: We evaluated the radiation dose of 99mTc-RGD, which has an acceptable effective radiation dose compare to the other Tc-99m labeled radio-tracers.

  16. Médicos residentes podem realizar com segurança e eficiência técnicas de Milligan-Morgan, Ferguson e grampeadores no tratamento cirúrgico das hemorróidas? Can residents safely and efficiently perform Milligan-Morgan, Ferguson and stapled hemorrhoidopexy?

    Directory of Open Access Journals (Sweden)

    Sérgio Carlos Nahas

    2011-09-01

    Full Text Available RACIONAL: A cirurgia para hemorróidas sintomáticas é necessária em quase 10% dos pacientes. Embora, a literatura sobre o tratamento cirúrgico da doença hemorroidária seja muito grande, os dados relativos à hemorroidectomia ou hemorroidopexia realizadas por residentes de treinamento é limitado. OBJETIVO: Analisar os resultados destes procedimentos em uma instituição de ensino. MÉTODOS: Foram analisados retrospectivamente os dados de todos os pacientes que se submeteram ao tratamento cirúrgico para hemorróidas entre1995 e 2007 em uma única instituição. Residentes supervisionados realizaram todos os procedimentos. As técnicas foram comparadas com base no tempo operatório, permanência hospitalar, morbidade e eficácia a longo prazo. RESULTADOS: Trezentos e trinta e três pacientes foram incluídos no estudo, 182 homens (54,6%, com idade média de 45,3 anos (± 12,02. Hemorróidas de terceiro grau foram a principal indicação (81,7%. Milligan-Morgan foi o procedimento mais comumente realizado (57%, seguido por Ferguson e hemorroidopexia grampeada. A média de tempo operatório foi significativamente menor no grupo hemorroidopexia grampeada quando comparado com os procedimentos abertos e fechados: 49,4 ± 29,3 min vs 61,1 ± 26,5 e 67,1 ± 28,3, respectivamente (p=0,0034. Não houve diferença estatisticamente significativa entre os grupos quanto às complicações pós-operatórias ou à taxa de reoperação. O tempo de internação foi significativamente maior no grupo Milligan-Morgan quando comparado com Ferguson e grampeamento (1,41 ± 0,86 dias vs 1,19 ± 0,43 vs 1,16 ± 0,37, respectivamente. Recorrência sintomática, taxas de reoperação e o uso de ligadura elástica foram semelhantes entre os grupos. CONCLUSÃO: Os residentes sob supervisão pode executar Milligan-Morgan, Ferguson e grampeamento hemorroidário com baixa incidência de complicações e bons resultados a longo prazo. O grampeamento foi associado com menor

  17. Massiv "børnedødelighed" blandt restauranter

    DEFF Research Database (Denmark)

    Hjalager, Anne-Mette

    1998-01-01

    Artiklen påviser på basis af statistik fra IDA databasen, at restauranter hvert år nedlægges og oprettes i stort tal. Artiklen diskuterer ulemper i forhold til professionalisering.......Artiklen påviser på basis af statistik fra IDA databasen, at restauranter hvert år nedlægges og oprettes i stort tal. Artiklen diskuterer ulemper i forhold til professionalisering....

  18. A budget impact analysis of parenteral iron treatments for iron deficiency anemia in the UK: reduced resource utilization with iron isomaltoside 1000.

    Science.gov (United States)

    Pollock, Richard F; Muduma, Gorden

    2017-01-01

    The reported prevalence of iron deficiency anemia (IDA) varies widely but estimates suggest that 3% of men and 8% of women have IDA in the UK. Parenteral iron is indicated for patients intolerant or unresponsive to oral iron or requiring rapid iron replenishment. This study evaluated differences in the cost of treating these patients with iron isomaltoside (Monofer ® , IIM) relative to other intravenous iron formulations. A budget impact model was developed to evaluate the cost of using IIM relative to ferric carboxymaltose (Ferinject ® , FCM), low molecular weight iron dextran (Cosmofer ® , LMWID), and iron sucrose (Venofer ® , IS) in patients with IDA. To establish iron need, iron deficits were modeled using a simplified dosing table. The base case analysis was conducted over 1 year in patients with IDA with mean bodyweight of 82.4 kg (SD 22.5 kg) and hemoglobin levels of 9.99 g/dL (SD 1.03 g/dL) based on an analysis of patient characteristics in IDA trials. Costs were modeled using UK health care resource groups. Using IIM required 1.3 infusions to correct the mean iron deficit, compared with 1.3, 1.8, and 7.7 with LMWID, FCM, and IS, respectively. Patients using IIM required multiple infusions in 35% of cases, compared with 35%, 77%, and 100% of patients with LMWID, FCM, and IS, respectively. Total costs were estimated to be GBP 451 per patient with IIM or LMWID, relative to GBP 594 with FCM (a GBP 143 or 24% saving with IIM) or GBP 2,600 with IS (a GBP 2,149 or 83% saving with IIM). Using IIM or LMWID in place of FCM or IS resulted in a marked reduction in the number of infusions required to correct iron deficits in patients with IDA. The reduction in infusions was accompanied by substantial reductions in cost relative to FCM and IS over 1 year.

  19. Bidirectional transport of iminodiacetic organic anion analogues between plasma and hepatocyte

    International Nuclear Information System (INIS)

    Peters, A.M.; Myers, M.J.; Mohammadtaghi, S.; Mubashar, M.; Mathie, R.T.

    1998-01-01

    The kinetics of organic anions are well described and back-diffusion from hepatocyte to plasma is accepted. Although iminodiacetic (IDA) analogues, as organic anions, should also show bidirectional transport between hepatocyte and plasma, this has not been directly demonstrated heretofore. The aim of this study was to directly demonstrate back-diffusion and to quantify it in terms of its fractional rate constant. Kinetics of diethyl IDA were studied in three anaesthetised dogs in which femoral arterial and hepatic venous samples were obtained after injection of tracer into (a) a peripheral vein or (b) hepatic artery or portal vein. Arterial time-concentration curves were also compared between peripheral venous and either hepatic arterial or portal venous injections. Time-activity curves were recorded from regions of interest over the cardiac blood pool and peripheral hepatic parenchyma in 30 patients undergoing routine IDA hepatobiliary imaging with diethyl IDA or mebrofenin and fractional rate constants of clearance of IDA from the hepatocyte compared between compartmental and deconvolution analyses. After peripheral injection in dogs, there was an early arteriovenous concentration gradient across the liver indicating an hepatocyte extraction fraction in the three animals of 0.9, 0.8 and 0.6. The net extraction fraction decreased exponentially over 40 min. Time-concentration curves from hepatic vein and femoral artery were virtually superimposed following intrahepatic injections. Peripheral arterial curves, however, had different shapes according to whether injections were intrahepatic or peripheral, and were consistent with significant back-diffusion. In clinical studies, the blood disappearance curves were fitted as the sum of two exponentials and the liver curves as the difference of two exponentials (with rate constants denoted α 1 h and α 2 h ). Based on compartmental analysis of the blood curves, the sum of the fractional rate constants of tracer movement

  20. Expert recommendations for the diagnosis and treatment of iron-deficiency anemia during pregnancy and the postpartum period in the Asia-Pacific region.

    Science.gov (United States)

    Breymann, Christian; Bian, Xu-Ming; Blanco-Capito, Lourdes R; Chong, Christopher; Mahmud, Ghazala; Rehman, Rakhshanda

    2011-03-01

    Anemia during pregnancy and the postpartum period is commonly caused by iron deficiency and is a significant worldwide issue with severe consequences for both mother and developing fetus. From a worldwide perspective, iron-deficiency anemia (IDA) during pregnancy is highest in the Asia-Pacific region; however, there has been little guidance in this region for safe and effective treatment. An expert panel was convened to develop a concise and informative set of recommendations for the treatment of IDA in pregnant and postpartum women in the Asia-Pacific region. This manuscript provides these recommendations and aims to reduce the morbidity and mortality associated with IDA in pregnant and postpartum women in the Asia-Pacific region. The consensus recommendations define anemia as a hemoglobin (Hb) level iron, intravenous iron or red blood cell transfusion.

  1. Iron fortification of food: a strategy for control of iron deficiency anemia

    International Nuclear Information System (INIS)

    Ahmad, T.; BILAL, R.

    2001-01-01

    Iron Deficiency Anemia (IDA) is prevalent in the low socio-economic strata of population of developing countries. Most of the developed countries have well established programs of food fortification with iron. Many developing countries are initiating such programs and Pakistan is one of them. In the ninth 5 year plan of Pakistan, fortification of wheat flour with appropriate level and form of iron will be done to combat the IDA problem. The current paper summarizes the information regarding various fortificants that are being used for the control of IDA world over, along with some information on their effectiveness and bioavailability, where nuclear techniques have proven to be very useful. This will help in the initial planning of the National Program of wheat flour fortification trial in Pakistan. (author)

  2. Lammutamine - Ida Virumaa linnade sundseis = Snos - võnuzhdennoje sostojanije gorodov Ida-Virumaa / Samuel Golomb

    Index Scriptorium Estoniae

    Golomb, Samuel, 1957-

    2004-01-01

    Samal ajal kui Rakveres ja Jõhvis on kerkimas kinnisvara hinnad, muretsevad Kohtla-Järve, Kiviõli ja Püssi linnavõimud vanade ning tühjaksjäänud elamute lammutamise pärast. Koos lammutustöödega on Kiviõli linnavõimud tellinud uue kesklinna planeeringu

  3. Discrimination indices as screening tests for beta-thalassemic trait.

    Science.gov (United States)

    Ntaios, George; Chatzinikolaou, Anastasia; Saouli, Zoi; Girtovitis, Fotios; Tsapanidou, Maria; Kaiafa, Georgia; Kontoninas, Zisis; Nikolaidou, Androula; Savopoulos, Christos; Pidonia, Ifigenia; Alexiou-Daniel, Stiliani

    2007-07-01

    The two most frequent microcytic anemias are beta-thalassemic trait (beta-TT) and iron deficiency anemia (IDA). Several discrimination indices have been proposed to distinguish between these two conditions. These indices are derived from several simple red blood cell indices, like red blood cell (RBC) count, mean cell volume, and RBC distribution width (RDW), as these are provided by electronic cell counters. The purpose of the study is to examine the diagnostic accuracy of six discrimination indices in the differentiation between IDA and beta-TT. The six discrimination indices that were examined were as follows: Mentzer Index (MI), Green & King Index (G&K), RDW Index (RDWI), England & Fraser Index (E&F), RDW, and RBC count. We calculated these indices on 373 patients (205 men, 168 women) with beta-TT and 120 patients (50 men, 70 women) with IDA, as well as their sensitivity, specificity, positive and negative prognostic value, efficiency, and Youden's index (YI). G&K shows the highest reliability, followed by E&F, RBC count, MI, and RDWI. On the contrary, RDW completely failed to differentiate between IDA and beta-TT. G&K proved to be the most reliable index as it had the highest sensitivity (75.06%), efficiency (80.12%), and YI (70.86%) for the detection of beta-TT. These six discrimination indices cannot be relied on for a safe differential diagnosis between beta-TT and IDA. They do have high specificity, but their sensitivity for the detection of beta-TT is not satisfactory. Consequently, they cannot be used neither as a screening tool for beta-TT because they could result in a significant number of false negative results.

  4. Multi-country comparisons of energy performance: The index decomposition analysis approach

    International Nuclear Information System (INIS)

    Ang, B.W.; Xu, X.Y.; Su, Bin

    2015-01-01

    Index decomposition analysis (IDA) is a popular tool for studying changes in energy consumption over time in a country or region. This specific application of IDA, which may be called temporal decomposition analysis, has been extended by researchers and analysts to study variations in energy consumption or energy efficiency between countries or regions, i.e. spatial decomposition analysis. In spatial decomposition analysis, the main objective is often to understand the relative contributions of overall activity level, activity structure, and energy intensity in explaining differences in total energy consumption between two countries or regions. We review the literature of spatial decomposition analysis, investigate the methodological issues, and propose a spatial decomposition analysis framework for multi-region comparisons. A key feature of the proposed framework is that it passes the circularity test and provides consistent results for multi-region comparisons. A case study in which 30 regions in China are compared and ranked based on their performance in energy consumption is presented. - Highlights: • We conducted cross-regional comparisons of energy consumption using IDA. • We proposed two criteria for IDA method selection in spatial decomposition analysis. • We proposed a new model for regional comparison that passes the circularity test. • Features of the new model are illustrated using the data of 30 regions in China

  5. Iron Deficiency Anaemia in Pregnancy and Postpartum: Pathophysiology and Effect of Oral versus Intravenous Iron Therapy

    Directory of Open Access Journals (Sweden)

    Alhossain A. Khalafallah

    2012-01-01

    Full Text Available Nutritional iron-deficiency anaemia (IDA is the most common disorder in the world, affecting more than two billion people. The World Health Organization’s global database on anaemia has estimated a prevalence of 14% based on a regression-based analysis. Recent data show that the prevalence of IDA in pregnant women in industrialized countries is 17.4% while the incidence of IDA in developing countries increases significantly up to 56%. Although oral iron supplementation is widely used for the treatment of IDA, not all patients respond adequately to oral iron therapy. This is due to several factors including the side effects of oral iron which lead to poor compliance and lack of efficacy. The side effects, predominantly gastrointestinal discomfort, occur in a large cohort of patients taking oral iron preparations. Previously, the use of intravenous iron had been associated with undesirable and sometimes serious side effects and therefore was underutilised. However, in recent years, new type II and III iron complexes have been developed, which offer better compliance and toleration as well as high efficacy with a good safety profile. In summary, intravenous iron can be used safely for a rapid repletion of iron stores and correction of anaemia during and after pregnancy.

  6. Iron nutrition and premenopausal women: effects of poor iron status on physical and neuropsychological performance.

    Science.gov (United States)

    McClung, James P; Murray-Kolb, Laura E

    2013-01-01

    Iron is a nutritionally essential trace element that functions through incorporation into proteins and enzymes, many of which contribute to physical and neuropsychological performance. Poor iron status, including iron deficiency (ID; diminished iron stores) and iron deficiency anemia (IDA; poor iron stores and diminished hemoglobin), affects billions of people worldwide. This review focuses on physical and neuropsychological outcomes associated with ID and IDA in premenopausal women, as the prevalence of ID and IDA is often greater in premenopausal women than other population demographics. Recent studies addressing the physiological effects of poor iron status on physical performance, including work productivity, voluntary activity, and athletic performance, are addressed. Similarly, the effects of iron status on neurological performance, including cognition, affect, and behavior, are summarized. Nutritional countermeasures for the prevention of poor iron status and the restoration of decrements in performance outcomes are described.

  7. Impact on infants' cognitive development of antenatal exposure to iron deficiency disorder and common mental disorders.

    Directory of Open Access Journals (Sweden)

    Thach Duc Tran

    Full Text Available OBJECTIVES: The aim of this study was to examine the effects of antenatal exposure to iron deficiency anemia (IDA and common mental disorders (CMD on cognitive development of 6 months old infants in a developing country. METHODS: A prospective population-based study in a rural province in Vietnam, which enrolled pregnant women at 12-20 weeks gestation and followed them up with their infants until six months postpartum. Criteria for IDA were Hb 30 years and primiparity had an indirect adverse effect on infants' Bayley cognitive scores. CONCLUSIONS: These findings suggest that antenatal IDA and CMD both have adverse effects on child cognitive development, which if unrecognized and unaddressed are likely to be lasting. It is crucial that both these risks are considered by policy makers, clinicians, and researchers seeking to improve child cognitive function in developing countries.

  8. CTC Sentinel. Volume 4, Issue 8

    Science.gov (United States)

    2011-08-01

    the al-Qa`ida franchises in Saudi Arabia and Yemen merged after the Saudi branch had been effectively repressed by Saudi authorities. Bin Ladin...back into a deadly force relatively quickly. The group’s ability to recover from adversity demonstrates that al-Qa`ida franchises are adept at...suffers from numerous other challenges that divert attention from AQAP. It is running out of both oil and water, it has a huge unemployment and

  9. CTC Sentinel. January 2008, Volume 1 Issue 2. A Profile of Tehrik-i-Taliban Pakistan

    Science.gov (United States)

    2008-01-01

    executing attacks. By sharing information with other terrorist groups, al-Qa`ida became the “Jihad’s Franchise ” by using the internet to connect...of terrorist activities or causes. Recruiters can log into chat rooms or visit cyber- cafes to find receptive members of the public, especially the...the worst that globalization and advanced community technologies have to offer. Al-Qa`ida is a virtual “network of networks,” a jihadist franchise

  10. A Profile of Tehrik-i-Taliban Pakistan

    Science.gov (United States)

    2008-01-01

    executing attacks. By sharing information with other terrorist groups, al-Qa`ida became the “Jihad’s Franchise ” by using the internet to connect...terrorist activities or causes. Recruiters can log into chat rooms or visit cyber- cafes to find receptive members of the public, especially the...worst that globalization and advanced community technologies have to offer. Al-Qa`ida is a virtual “network of networks,” a jihadist franchise

  11. The Aoraki Mackenzie International Dark Sky Reserve and light pollution issues in New Zealand

    Science.gov (United States)

    Hearnshaw, John

    2015-08-01

    I will discuss the Aoraki Mackenzie International Dark Sky Reserve, recognized by IDA in 2012, and how the reserve is managed and promoted to the public to make them aware of light pollution issues and in order to promote star-gazing and astro-tourism. AMIDSR is the world's largest Dark Sky Reserve recognized by IDA and has gold tier status. We will have a Starlight festival in October to promote the Reserve to the public.

  12. Kevlar: Transitioning Helix for Research to Practice

    Science.gov (United States)

    2016-03-01

    x86 binaries, although it can be targeted to any platform that is targeted by IDA Pro. Currently, IDA Pro targets more than 40 processors and...effects its own transformations. Helix/Kevlar then automatically generates SPRI rules for any program variants by essentially performing a “ smart diff...execute permission on the pages of memory it uses, leaving only execute (but not write) permission on the code cache. Strata also watches for attempts

  13. CTC Sentinel. Volume 7, Issue 2, February 2014

    Science.gov (United States)

    2014-02-01

    types of threats it poses, and its future prospects. It finds that al-Shabab is a franchise with distinct components, the fastest growing of...ranks.5 Although not formally an al- Qa`ida franchise during this time, al- Shabab benefited from public relations support and advisers from al-Qa`ida.6...damaged its reputation among Somalis by blocking international food aid from entering most of its areas of control, denying that a famine existed

  14. Ailar Holzmann : "Meile on oluline, et õnnetusi ei juhtuks" / Ailar Holzmann ; interv. Gerli Romanovitsh

    Index Scriptorium Estoniae

    Holzmann, Ailar

    2006-01-01

    Ilmunud ka: Severnoje Poberezhje Ilmunud ka: Severnoje Poberezhje : Subbota 6. mai lk. 3. Jaanuarikuust Ida-Eesti päästekeskust juhtima asunud Ailar Holzmann tunnistab, et inimesed lahkuvad töölt madala palga tõttu. Kokku on Virumaal päästealal vajaka 130 töötajat. Arvamust avaldavad päästeameti peadirektor Mati Raidma ja Ida-Eesti päästekeskuse päästetöödeteenistuse juht Tauno Suurkivi

  15. A budget impact analysis of parenteral iron treatments for iron deficiency anemia in the UK: reduced resource utilization with iron isomaltoside 1000

    Directory of Open Access Journals (Sweden)

    Pollock RF

    2017-08-01

    Full Text Available Richard F Pollock,1 Gorden Muduma2 1Ossian Health Economics and Communications GmbH, Basel, Switzerland; 2Pharmacosmos A/S, Holbaek, Denmark Background and aims: The reported prevalence of iron deficiency anemia (IDA varies widely but estimates suggest that 3% of men and 8% of women have IDA in the UK. Parenteral iron is indicated for patients intolerant or unresponsive to oral iron or requiring rapid iron replenishment. This study evaluated differences in the cost of treating these patients with iron isomaltoside (Monofer®, IIM relative to other intravenous iron formulations. Methods: A budget impact model was developed to evaluate the cost of using IIM relative to ferric carboxymaltose (Ferinject®, FCM, low molecular weight iron dextran (Cosmofer®, LMWID, and iron sucrose (Venofer®, IS in patients with IDA. To establish iron need, iron deficits were modeled using a simplified dosing table. The base case analysis was conducted over 1 year in patients with IDA with mean bodyweight of 82.4 kg (SD 22.5 kg and hemoglobin levels of 9.99 g/dL (SD 1.03 g/dL based on an analysis of patient characteristics in IDA trials. Costs were modeled using UK health care resource groups. Results: Using IIM required 1.3 infusions to correct the mean iron deficit, compared with 1.3, 1.8, and 7.7 with LMWID, FCM, and IS, respectively. Patients using IIM required multiple infusions in 35% of cases, compared with 35%, 77%, and 100% of patients with LMWID, FCM, and IS, respectively. Total costs were estimated to be GBP 451 per patient with IIM or LMWID, relative to GBP 594 with FCM (a GBP 143 or 24% saving with IIM or GBP 2,600 with IS (a GBP 2,149 or 83% saving with IIM. Conclusion: Using IIM or LMWID in place of FCM or IS resulted in a marked reduction in the number of infusions required to correct iron deficits in patients with IDA. The reduction in infusions was accompanied by substantial reductions in cost relative to FCM and IS over 1 year. Keywords: iron

  16. CTC Sentinel. Volume 3, Issue 2, February 2010

    Science.gov (United States)

    2010-02-01

    difficulty of creating a Lebanese franchise , it is likely that al-Qa`ida has switched its strategy and gone underground.2 Clandestine terrorist...Of course, no leader belonging to al-Qa`ida central or to any of its franchises in the Middle East has made a pub- lic statement detailing a...Reilly was only prevented by his own incompetence when his bomb failed to detonate properly in the middle of a restaurant in Exeter in May 2008

  17. Euroopa püüab toime tulla idatööliste marsiga läände / Sarah Laitner, Stefan Wagstyl

    Index Scriptorium Estoniae

    Laitner, Sarah

    2006-01-01

    Mitmed EL-i nn. vanad riigid kõhklevad, kas kaotada piirangud Ida-Euroopa tööjõule. Briti valitsuse väitel on riigi majandus tööturu piirangu kaotamisest kasu saanud, samas on suurenenud noorte pikaajaline töötus. Ida-Euroopas on aga mõnes valdkonnas tekkinud tööjõupuudus. Lisa: Iiri pelgab olukorda tööjõuturul. Tabel: Riikide suhtumine tööjõu vaba liikumise piirangutesse

  18. Double enzymatic hydrolysis preparation of heme from goose blood and microencapsulation to promote its stability and absorption.

    Science.gov (United States)

    Wang, Baowei; Cheng, Fansheng; Gao, Shun; Ge, Wenhua; Zhang, Mingai

    2017-02-15

    Iron deficiency anemia (IDA) is the most common nutritional deficiency worldwide. This deficiency could be solved by preparing stable, edible, and absorbable iron food ingredients using environmentally friendly methods. This study investigated enzymatic hydrolysis and microencapsulation process of goose blood. The physicochemical properties, stabilities of the microencapsulated goose blood hydrolysate (MGBH) and a supplement for rats with IDA were also evaluated. The results showed that the synergetic hydrolytic action of neutrase and alkaline protease significantly increased the heme-releasing efficiency. The heme was then microencapsulated using sodium caseinate, maltodextrin and carboxymethyl cellulose (CMC) as the edible wall material, and the encapsulation efficiency of the product reached 98.64%. Meanwhile, favorable thermal, storage and light stabilities were observed for the microencapsulation. It was found that MGBH can significantly improve the body weight and hematological parameters of IDA Wistar rat. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Biological behaviour of some 67Ga and 64Cu chelates

    International Nuclear Information System (INIS)

    Leonovicova, T.; Angelis, B.; Cifka, J.; Cifkova, I.

    1984-01-01

    Chelates of 67 Ga and 64 Cu with iminodiacetic acid (IDA) and its two phenyl derivatives as well as with nitrilotriacetic acid (NTA) and benzylnitrilotriacetic acid (BNTA) were prepared. All the chelates were found to be negatively charged. A study of the biological distribution of these chelates in rats during time intervals of 3 to 180 min showed that the chelate of 67 Ga with IDA substituted at a phenyl by a hydrophobic substituent is excreted by the kidneys into the urine at a much higher rate than the IDA chelate of 67 Ga. The excretion of NTA and BNTA chelates of 67 Ga is the opposite. Blood clearance of 64 Cu chelates is more rapid than that of 67 Ga chelates. Chelates of 64 Cu accumulate in the liver and with the bile are slowly excreted into the intestines, urinary excretion is negligible. (author)

  20. "How often? How much? Where from?" knowledge, attitudes, and practices of mothers and health workers to iron supplementation program for children under five in rural Tamil Nadu, south India.

    Science.gov (United States)

    Kwon, Hye Jin; Ramasamy, Rajkumar; Morgan, Alison

    2014-07-01

    Iron deficiency anemia (IDA) affects 70% of under-5 children in India. The primary prevention strategy is regular iron supplementation. Little is known about what helps families adhere to daily iron supplementation. Our study explored the knowledge, attitudes, and practices of mothers and village health workers (VHWs) involved in a community health program in one hill district of Tamil Nadu. We conducted 30 semistructured interviews and 3 group discussions involving mothers, VHWs, and community stakeholders. Knowledge of IDA was widespread, yet no children were receiving the iron supplementation as recommended. The main determinants to adherence included the perception of its need, the ease of access, and the activity of VHWs. Preventive care requiring daily supplements is challenging. Our study suggests that increasing community awareness of mild anemia, simplifying dosage instructions, and further strengthening the supportive environment for VHWs would help in reducing the prevalence of IDA. © 2013 APJPH.

  1. New insights into iron deficiency and iron deficiency anemia.

    Science.gov (United States)

    Camaschella, Clara

    2017-07-01

    Recent advances in iron metabolism have stimulated new interest in iron deficiency (ID) and its anemia (IDA), common conditions worldwide. Absolute ID/IDA, i.e. the decrease of total body iron, is easily diagnosed based on decreased levels of serum ferritin and transferrin saturation. Relative lack of iron in specific organs/tissues, and IDA in the context of inflammatory disorders, are diagnosed based on arbitrary cut offs of ferritin and transferrin saturation and/or marker combination (as the soluble transferrin receptor/ferritin index) in an appropriate clinical context. Most ID patients are candidate to traditional treatment with oral iron salts, while high hepcidin levels block their absorption in inflammatory disorders. New iron preparations and new treatment modalities are available: high-dose intravenous iron compounds are becoming popular and indications to their use are increasing, although long-term side effects remain to be evaluated. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Helicobacter pylori infection and low dietary iron alter behavior, induce iron deficiency anemia, and modulate hippocampal gene expression in female C57BL/6 mice

    Science.gov (United States)

    Burns, Monika; Amaya, Aldo; Bodi, Caroline; Ge, Zhongming; Bakthavatchalu, Vasudevan; Ennis, Kathleen; Wang, Timothy C.; Georgieff, Michael

    2017-01-01

    Helicobacter pylori (H.pylori), a bacterial pathogen, is a causative agent of gastritis and peptic ulcer disease and is a strong risk factor for development of gastric cancer. Environmental conditions, such as poor dietary iron resulting in iron deficiency anemia (IDA), enhance H.pylori virulence and increases risk for gastric cancer. IDA affects billions of people worldwide, and there is considerable overlap between regions of high IDA and high H.pylori prevalence. The primary aims of our study were to evaluate the effect of H.pylori infection on behavior, iron metabolism, red blood cell indices, and behavioral outcomes following comorbid H. pylori infection and dietary iron deficiency in a mouse model. C57BL/6 female mice (n = 40) were used; half were placed on a moderately iron deficient (ID) diet immediately post-weaning, and the other half were maintained on an iron replete (IR) diet. Half were dosed with H.pylori SS1 at 5 weeks of age, and the remaining mice were sham-dosed. There were 4 study groups: a control group (-Hp, IR diet) as well as 3 experimental groups (-Hp, ID diet; +Hp, IR diet; +Hp,ID diet). All mice were tested in an open field apparatus at 8 weeks postinfection. Independent of dietary iron status, H.pylori -infected mice performed fewer exploratory behaviors in the open field chamber than uninfected mice (pmice on an ID diet (both pmice compared to all other study groups. H.pylori infection caused IDA in mice maintained on a marginal iron diet. The mouse model developed in this study is a useful model to study the neurologic, behavioral, and hematologic impact of the common human co-morbidity of H. pylori infection and IDA. PMID:28355210

  3. Iron status of young children in Europe.

    Science.gov (United States)

    van der Merwe, Liandré F; Eussen, Simone R

    2017-12-01

    Iron deficiency (ID) is common in young children aged 6-36 mo. Although the hazards associated with iron deficiency anemia (IDA) are well known, concerns about risks associated with excess iron intake in young children are emerging. To characterize iron status in Europe, we describe the prevalence of ID, IDA, iron repletion, and excess stores with the use of published data from a systematic review on iron intake and deficiency rates, combined with other selected iron status data in young European children. Various definitions for ID and IDA were applied across studies. ID prevalence varied depending on socioeconomic status and type of milk fed (i.e., human or cow milk or formula). Without regard to these factors, ID was reported in 3-48% of children aged ≥12 mo across the countries. For 6- to 12-mo-old infants, based on studies that did not differentiate these factors, ID prevalence was 4-18%. IDA was iron status data from a sample of healthy Western European children aged 12-36 mo, 69% were iron replete, and the 97.5th percentile for serum ferritin (SF) was 64.3 μg/L. In another sample, 79% of 24-mo-old children were iron replete, and the 97.5th percentile for SF was 57.3 μg/L. Average iron intake in most countries studied was close to or below the UK's Recommended Dietary Allowance. In conclusion, even in healthy European children aged 6-36 mo, ID is still common. In Western European populations for whom data were available, approximately three-quarters of children were found to be iron replete, and excess iron stores (SF >100 μg/L) did not appear to be a concern. Consensus on the definitions of iron repletion and excess stores, as well as on ID and IDA, is needed. © 2017 American Society for Nutrition.

  4. Iron Fortified Complementary Foods Containing a Mixture of Sodium Iron EDTA with Either Ferrous Fumarate or Ferric Pyrophosphate Reduce Iron Deficiency Anemia in 12- to 36-Month-Old Children in a Malaria Endemic Setting: A Secondary Analysis of a Cluster-Randomized Controlled Trial.

    Science.gov (United States)

    Glinz, Dominik; Wegmüller, Rita; Ouattara, Mamadou; Diakité, Victorine G; Aaron, Grant J; Hofer, Lorenz; Zimmermann, Michael B; Adiossan, Lukas G; Utzinger, Jürg; N'Goran, Eliézer K; Hurrell, Richard F

    2017-07-14

    Iron deficiency anemia (IDA) is a major public health problem in sub-Saharan Africa. The efficacy of iron fortification against IDA is uncertain in malaria-endemic settings. The objective of this study was to evaluate the efficacy of a complementary food (CF) fortified with sodium iron EDTA (NaFeEDTA) plus either ferrous fumarate (FeFum) or ferric pyrophosphate (FePP) to combat IDA in preschool-age children in a highly malaria endemic region. This is a secondary analysis of a nine-month cluster-randomized controlled trial conducted in south-central Côte d'Ivoire. 378 children aged 12-36 months were randomly assigned to no food intervention ( n = 125; control group), CF fortified with 2 mg NaFeEDTA plus 3.8 mg FeFum for six days/week ( n = 126; FeFum group), and CF fortified with 2 mg NaFeEDTA and 3.8 mg FePP for six days/week ( n = 127; FePP group). The outcome measures were hemoglobin (Hb), plasma ferritin (PF), iron deficiency (PF anemia (Hb iron deficiency with or without anemia ( p = 0.068). IDA prevalence sharply decreased in the FeFum (32.8% to 1.2%, p anemia. These data indicate that, despite the high endemicity of malaria and elevated inflammation biomarkers (C-reactive protein or α-1-acid-glycoprotein), IDA was markedly reduced by provision of iron fortified CF to preschool-age children for 9 months, with no significant differences between a combination of NaFeEDTA with FeFum or NaFeEDTA with FePP. However, there was no overall effect on anemia, suggesting most of the anemia in this setting is not due to ID. This trial is registered at clinicaltrials.gov (NCT01634945).

  5. Energy saving analysis and management modeling based on index decomposition analysis integrated energy saving potential method: Application to complex chemical processes

    International Nuclear Information System (INIS)

    Geng, Zhiqiang; Gao, Huachao; Wang, Yanqing; Han, Yongming; Zhu, Qunxiong

    2017-01-01

    Highlights: • The integrated framework that combines IDA with energy-saving potential method is proposed. • Energy saving analysis and management framework of complex chemical processes is obtained. • This proposed method is efficient in energy optimization and carbon emissions of complex chemical processes. - Abstract: Energy saving and management of complex chemical processes play a crucial role in the sustainable development procedure. In order to analyze the effect of the technology, management level, and production structure having on energy efficiency and energy saving potential, this paper proposed a novel integrated framework that combines index decomposition analysis (IDA) with energy saving potential method. The IDA method can obtain the level of energy activity, energy hierarchy and energy intensity effectively based on data-drive to reflect the impact of energy usage. The energy saving potential method can verify the correctness of the improvement direction proposed by the IDA method. Meanwhile, energy efficiency improvement, energy consumption reduction and energy savings can be visually discovered by the proposed framework. The demonstration analysis of ethylene production has verified the practicality of the proposed method. Moreover, we can obtain the corresponding improvement for the ethylene production based on the demonstration analysis. The energy efficiency index and the energy saving potential of these worst months can be increased by 6.7% and 7.4%, respectively. And the carbon emissions can be reduced by 7.4–8.2%.

  6. Rapidly Dissolving Microneedle Patches for Transdermal Iron Replenishment Therapy.

    Science.gov (United States)

    Maurya, Abhijeet; Nanjappa, Shivakumar H; Honnavar, Swati; Salwa, M; Murthy, S Narasimha

    2018-02-17

    The prevalence of iron deficiency anemia (IDA) is predominant in women and children especially in developing countries. The disorder affects cognitive functions and physical activity. Although oral iron supplementation and parenteral therapy remains the preferred choice of treatment, gastric side effects and risk of iron overload decreases adherence to therapy. Transdermal route is an established approach, which circumvents the side effects associated with conventional therapy. In this project, an attempt was made to investigate the use of rapidly dissolving microneedles loaded with ferric pyrophosphate (FPP) as a potential therapeutic approach for management of IDA. Microneedle array patches were made using the micromolding technique and tested in vitro using rat skin to check the duration required for dissolution/disappearance of needles. The ability of FPP-loaded microneedles to replenish iron was investigated in anemic rats. Rats were fed iron-deficient diet for 5 weeks to induce IDA following which microneedle treatment was initiated. Recovery of rats from anemic state was monitored by measuring hematological and biochemical parameters. Results from in vivo study displayed significant improvements in hemoglobin and serum iron levels after 2-week treatment with FPP-loaded microneedles. The study effectively demonstrated the potential of microneedle-mediated iron replenishment for treatment of IDA. Copyright © 2018 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

  7. Iminodiacetic acid functionalized polypyrrole modified electrode as Pb(II) sensor: Synthesis and DPASV studies

    International Nuclear Information System (INIS)

    Joseph, Alex; Subramanian, Sankaran; Ramamurthy, Praveen C.; Sampath, Srinivasan; Kumar, R. Vasant; Schwandt, Carsten

    2014-01-01

    Graphical abstract: - Abstract: An electrochemical lead ion sensor has been developed by modification of carbon paste electrode (CPE) using polypyrrole functionalized with iminodiacetic acid (IDA-PPy) containing carboxyl group. The electrochemical response of Pb 2+ ion on the IDA-PPy modified CPE has been evaluated and the controling parameters have been optimized using differential pulse anodic stripping voltammetry (DPASV). The IDA-PPy modified CPE shows a linear correlation for Pb 2+ concentrations in the range of 1 × 10 −6 to 5 × 10 −9 M and the lower detection limit of Pb 2+ has been found to be 9.6 × 10 −9 M concentration. Other tested metal ions, namely Cu 2+ , Cd 2+ , Co 2+ , Hg 2+ , Ni 2+ and Zn 2+ , do not exhibit any voltammetric stripping response below 1 × 10 −7 M concentration. However, the Pb 2+ response is affected in the presence of molar equivalents or higher concentrations of Cu 2+ , Cd 2+ and Co 2+ ions in binary systems with Pb 2+ , consequent to their ability to bind with iminodiacetic acid, while Hg 2+ , Ni 2+ and Zn 2+ do not interfere at all. A good correlation has been observed between the lead concentrations as analyzed by DPASV using IDA-PPy modified CPE and atomic absorption spectrophotometry for a lead containing industrial effluent sample

  8. Iron Deficiency in Long-Term Parenteral Nutrition Therapy.

    Science.gov (United States)

    Hwa, Yi L; Rashtak, Shahrooz; Kelly, Darlene G; Murray, Joseph A

    2016-08-01

    Iron is not routinely added to parenteral nutrition (PN) formulations in the United States because of the risk of anaphylaxis and concerns about incompatibilities. Studies have shown that iron dextran in non-lipid-containing PN solutions is safe. Data are limited on iron status, prevalence of iron deficiency anemia (IDA), and efficacy of intravenous iron infusion in long-term home PN (HPN). We aimed to determine the incidence of IDA and to examine the effectiveness of parenteral iron replacement in patients receiving HPN. Medical records of patients receiving HPN at the Mayo Clinic from 1977 to 2010 were reviewed. Diagnoses, time to IDA development, and hemoglobin, ferritin, and mean corpuscular volume (MCV) values were extracted. Response of iron indices to intravenous iron replacement was investigated. Of 185 patients (122 women), 60 (32.4%) were iron deficient. Five patients were iron deficient, and 18 had unknown iron status before HPN. Of 93 patients who had sufficient iron storage, 37 had IDA development after a mean of 27.2 months (range, 2-149 months) of therapy. Iron was replaced by adding maintenance iron dextran to PN or by therapeutic iron infusion. Patients with both replacement methods had significant improvement in iron status. With intravenous iron replacement, mean ferritin increased from 10.9 to 107.6 mcg/L (P Parenteral and Enteral Nutrition.

  9. Screening and identification of steroidal saponins from Anemarrhena asphodeloides employing UPLC tandem triple quadrupole linear ion trap mass spectrometry.

    Science.gov (United States)

    Xia, Yong-Gang; Guo, Xin-Dong; Liang, Jun; Yang, Bing-You; Kuang, Hai-Xue

    2017-09-01

    This study presents a practical and valid strategy for the screening and structural characterization of Anemarrhena asphodeloides Bge steroidal saponins (SSs) using ultra-high performance liquid chromatography coupled with triple quadrupole linear ion trap mass spectrometry. The whole analytical protocols integrate four-step procedures in the positive mode: (1) rational deduction of mass fragmentation pathways of A. asphodeloides SSs; (2) untargeted screening of potential A. asphodeloides SSs by multiple-ion monitoring-information-dependent-acquiring-enhanced product ion (MIM-IDA-EPI) scan through reverse phase liquid chromatography; (3) comprehensive construction of an ammoniated precursor ion database by combining untargeted MIM-IDA-EPI scans and data literature; and (4) structural interpretation of targeted A. asphodeloides SSs using MIM-IDA-EPI and multiple reaction monitoring (MRM)-IDA-EPI with an energy-resolved technique. The protocols were used to analyze SSs in A. asphodeloides; of the 87 detected SSs that were unambiguously characterized or tentatively identified, 19 compounds were the first to be reported from A. asphodeloides and 13 ones were characterized as potential new compounds. Accuracy of the analytical procedure was demonstrated by structural identification of three SSs by NMR spectroscopy. The proposed schemes hold an excellent promise in the structural prediction and interpretation of complex SSs from plant medicines by mass spectrometry. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Understanding and Engaging the Muslims of the Southern Philippines

    Science.gov (United States)

    2012-06-01

    is a US- only theme. It is true that American culture is very popular in the Philippines—our movies, music and fast-food restaurants are very much in...mosques (snicker) and they love to pray (mocking tone). But they are not kind. They are everywhere in the PI, selling things, like the Chinese ...MILF, Abu Sayyaf and Jemaah Islamiyah and Al-Qa’ida . JI is from Indonesia and Malaysia .  (US) al-Qa’ida say/believe they are fighting evil

  11. Chelating capture and magnetic removal of non-magnetic heavy metal substances from soil

    OpenAIRE

    Liren Fan; Jiqing Song; Wenbo Bai; Shengping Wang; Ming Zeng; Xiaoming Li; Yang Zhou; Haifeng Li; Haiwei Lu

    2016-01-01

    A soil remediation method based on magnetic beneficiation is reported. A new magnetic solid chelator powder, FS@IDA (core-shell Fe3O4@SiO2 nanoparticles coated with iminodiacetic acid chelators), was used as a reactive magnetic carrier to selectively capture non-magnetic heavy metals in soil by chelation and removal by magnetic separation. FS@IDA was prepared via inorganic-organic and organic synthesis reactions that generated chelating groups on the surface of magnetic, multi-core, core-shel...

  12. The Secret of Future Victories

    Science.gov (United States)

    1992-02-01

    Copy S of 320 copies AD--A25 0 718 IDA PAPER P-265 3 THE SECRET OF FUTURE VICTORIES Paul F. Gormnan General, USA (Retired) DTIC 05M February 1992 NAY...TYPE AND DATES COVERED IFebruary 1992 Final--June 1991-January 1992 4. TITLE AND SUBTITLE 5. FUNDING NUMBERS The Secret of Future Victories C -MDA...8 2N0-102 IDA PAPER P-2653 THE SECRET OF FUTURE VICTORIES Paul F. Gorman General. LUSA (Retired) February 1992 Approved for public release

  13. Comparing structural decomposition analysis and index

    International Nuclear Information System (INIS)

    Hoekstra, Rutger; Van den Bergh, Jeroen C.J.M.

    2003-01-01

    To analyze and understand historical changes in economic, environmental, employment or other socio-economic indicators, it is useful to assess the driving forces or determinants that underlie these changes. Two techniques for decomposing indicator changes at the sector level are structural decomposition analysis (SDA) and index decomposition analysis (IDA). For example, SDA and IDA have been used to analyze changes in indicators such as energy use, CO 2 -emissions, labor demand and value added. The changes in these variables are decomposed into determinants such as technological, demand, and structural effects. SDA uses information from input-output tables while IDA uses aggregate data at the sector-level. The two methods have developed quite independently, which has resulted in each method being characterized by specific, unique techniques and approaches. This paper has three aims. First, the similarities and differences between the two approaches are summarized. Second, the possibility of transferring specific techniques and indices is explored. Finally, a numerical example is used to illustrate differences between the two approaches

  14. Selection of mode for the measurement of lead isotope ratios by inductively coupled plasma mass spectrometry and its application to milk powder analysis

    International Nuclear Information System (INIS)

    Dean, J.R.; Ebdon, L.; Massey, R.

    1987-01-01

    An investigation into the selection of the optimum mode for the measurement of isotope ratios in inductively coupled plasma mass spectrometry (ICP-MS) is reported, with particular reference to lead isotope ratios. Variation in the accuracy and precision achievable using the measurement modes of scanning and peak jumping are discussed. It is concluded that if sufficient sample and time are available, scanning gives best accuracy and precision. Isotope dilution analysis (IDA) has been applied to the measurement of the lead content of two dried milk powders of Australian and European origin introduced as slurries into ICP-MS. Differences in the lead isotope ratios in the two milk powders were investigated and the total lead content determined by IDA. Isotope dilution analysis permitted accurate data to be obtained with an RSD of 4.2% or milk powder containing less than 30 ng g -1 of lead. The ICP-MS technique is confirmed as a useful tool for IDA. (author)

  15. Integrated data analysis of fusion diagnostics by means of the Bayesian probability theory

    International Nuclear Information System (INIS)

    Fischer, R.; Dinklage, A.

    2004-01-01

    Integrated data analysis (IDA) of fusion diagnostics is the combination of heterogeneous diagnostics to obtain validated physical results. Benefits from the integrated approach result from a systematic use of interdependencies; in that sense IDA optimizes the extraction of information from sets of different data. For that purpose IDA requires a systematic and formalized error analysis of all (statistical and systematic) uncertainties involved in each diagnostic. Bayesian probability theory allows for a systematic combination of all information entering the diagnostic model by considering all uncertainties of the measured data, the calibration measurements, and the physical model. Prior physics knowledge on model parameters can be included. Handling of systematic errors is provided. A central goal of the integration of redundant or complementary diagnostics is to provide information to resolve inconsistencies by exploiting interdependencies. A comparable analysis of sets of diagnostics (meta-diagnostics) is performed by combining statistical and systematical uncertainties with model parameters and model uncertainties. Diagnostics improvement and experimental optimization and design of meta-diagnostics will be discussed

  16. In Brief: Online database for instantaneous streamflow data

    Science.gov (United States)

    Showstack, Randy

    2007-11-01

    Access to U.S. Geological Survey (USGS) historical instantaneous streamflow discharge data, dating from around 1990, is now available online through the Instantaneous Data Archive (IDA), the USGS announced on 14 November. In this new system, users can find streamflow information reported at the time intervals at which it is collected, typically 15-minute to hourly intervals. Although instantaneous data have been available for many years, they were not accessible through the Internet. Robert Hirsch, USGS Associate Director of Water, said, ``A user-friendly archive of historical instantaneous streamflow data is important to many different users for such things as floodplain mapping, flood modeling, and estimating pollutant transport.''The site currently has about 1.5 billion instantaneous data values from 5500 stream gages in 26 states. The number of states and stream gages with data will continue to increase, according to the USGS. For more information, visit the Web site: http://ida.water.usgs.gov/ida/.

  17. Research on Protective Effect and Mechanism of Idazoxan on lps Attacked Acute Hepatic Injury

    Science.gov (United States)

    Zhu, Junyu; Ying, Shangqi; Kang, Wenyuan; Huang, Wenjuan; Liang, Huaping

    2018-01-01

    Objective: To observe the protection effect of Idazoxan (IDA) on LPS induced acute hepatic injury, and to explore its action mechanism. Methods: 60 adult C57BL/6 mice were divided into a control group (20 mice, intraperitoneal injection of phosphate buffer), a model group (20 mice, intraperitoneal injection of LPS 10 mg/kg) and a agmatine group (20 mice, intraperitoneal injection of LPS 10 mg/kg and agmatine 200 mg/kg) according to random number table method. Blood and liver tissue were collected for preparation of tissue homogenate. Enzyme-linked immunosorbent assay (ELISA) was adopted for detecting tumor necrosis factor-α (TNF-α) and interleukin (IL- 1β and IL - 6) contents in the serum and liver tissue at 24h after molding. Automatic biochemical analyzer is used for determining alanine transaminase (ALT), aspartate aminotransferase (AST) and lactate dehydrogenase (LDH) level at 24h after molding; The liver tissue pathology changes were observed at 24h after molding. Macrophage RAW264.7 cells were stimulated by 10 μg/mL LPS and with or without IDA (100 μmol/L). 2’, 7’-dichlorofluoresce in diacetate (DCFH-DA) was used as a fluorescent probe for detection of intracellular reactive oxygen species (ROS) level; qRT - PCR method was used for detecting antioxidant enzymes HO-1 and NQO-1 mRNA expression level at 2h, 4h and 8 h. Results: mice in the model group suffered from depression, curling and food water forbidding at 6h after molding. Mice in the Idazoxan group have obviously better spirit and activity than that of model group. The serum ALT, AST and LDH level of LPS attacked acute hepatic injury mice can be effectively alleviated after Idazoxan treatment. The expression of proinflammatory factor TNF-α and IL-6 in the liver can be reduced. The liver showed obvious pathological changes at 24 h after injection, such as liver cell swelling, necrosis, congestion, inflammatory cell infiltration, etc.; The liver cell injury was prominently alleviated in IDA

  18. Theoretical studies of the structures and local aromaticity of conjugated polycyclic hydrocarbons using three aromatic indices

    Science.gov (United States)

    Sakai, Shogo; Kita, Yuki

    2013-07-01

    The structures and local aromaticity of some conjugated polycyclic hydrocarbons (from the butadienoid, acene, and phenylene series) are studied using ab initio MO and density functional methods. The aromaticities of the molecules are estimated using three indices: the nucleus-independent chemical shift (NICS), the harmonic oscillator model of aromaticity (HOMA), and the index of deviation from aromaticity (IDA). Assessment of the relationships between the structures and the aromatic indices shows that the IDA values correspond best to the characteristics of the conjugated polycyclic hydrocarbon structures.

  19. A fast-track anaemia clinic in the Emergency Department: cost-analysis of intravenous iron administration for treating iron-deficiency anaemia.

    Science.gov (United States)

    Quintana-Díaz, Manuel; Muñoz-Romo, Raúl; Gómez-Ramírez, Susana; Pavía, José; Borobia, Alberto M; García-Erce, José A; Muñoz, Manuel

    2017-09-01

    A fast-track anaemia clinic (FTAC) for the management of moderate-to-severe iron-deficiency anaemia (IDA) was established in our Emergency Department in 2010. In this FTAC, the replacement of packed red cell transfusion by ferric carboxymaltose administration was proven to be safe and effective. The aim of this study was a cost-analysis of IDA management in the FTAC, comparing this management with the previous standard care pathway consisting of packed red cell transfusion, if needed, and referral to outpatient specialised care. A cost study was performed for patients with IDA who were at risk of requiring transfusion (haemoglobin costs in the FTAC were compared to those theoretically incurred if these patients had been managed using the standard care pathway. In addition, a sensitivity analysis considering variations of up to ±30% in ferric carboxymaltose and packed red cell acquisition costs was performed (49 possible scenarios). Between 2012 and 2015, 238 IDA patients were treated in the FTAC. The average treatment cost was € 594±337/patient in the FTAC group and € 672±301/patient in the standard care pathway group, with a saving of € 78±28/patient (95% CI, 22-133; pcosts in the FTAC (€ 480-722/patient), compared with those of the standard care pathway (€ 550-794/patient), resulted in significant cost-savings for all studied scenarios (€ 51-104/patient; pcost-saving compared with the standard care pathway.

  20. Primary Care Provider Views About Usefulness and Dissemination of a Web-Based Depression Treatment Information Decision Aid.

    Science.gov (United States)

    Beaulac, Julie; Westmacott, Robin; Walker, John R; Vardanyan, Gohar

    2016-06-08

    Decisions related to mental health are often complex, problems often remain undetected and untreated, information unavailable or not used, and treatment decisions frequently not informed by best practice or patient preferences. The objective of this paper was to obtain the opinions of health professionals working in primary health care settings about a Web-based information decision aid (IDA) for patients concerning treatment options for depression and the dissemination of the resources in primary care settings. Participants were recruited from primary care clinics in Winnipeg and Ottawa, Canada, and included 48 family physicians, nurses, and primary care staff. The study design was a qualitative framework analytic approach of 5 focus groups. Focus groups were conducted during regular staff meetings, were digitally recorded, and transcripts created. Analysis involved a content and theme analysis. Seven key themes emerged including the key role of the primary care provider, common questions about treatments, treatment barriers, sources of patient information, concern about quality and quantity of available information, positive opinions about the IDA, and disseminating the IDA. The most common questions mentioned were about medication and side effects and alternatives to medication. Patients have limited access to alternative treatment options owing to cost and availability. Practitioners evaluated the IDA positively. The resources were described as useful, supportive of providers' messages, and accessible for patients. There was unanimous consensus that information needs to be available electronically through the Internet.

  1. Combining multi-criteria decision analysis and mini-health technology assessment: A funding decision-support tool for medical devices in a university hospital setting.

    Science.gov (United States)

    Martelli, Nicolas; Hansen, Paul; van den Brink, Hélène; Boudard, Aurélie; Cordonnier, Anne-Laure; Devaux, Capucine; Pineau, Judith; Prognon, Patrice; Borget, Isabelle

    2016-02-01

    At the hospital level, decisions about purchasing new and oftentimes expensive medical devices must take into account multiple criteria simultaneously. Multi-criteria decision analysis (MCDA) is increasingly used for health technology assessment (HTA). One of the most successful hospital-based HTA approaches is mini-HTA, of which a notable example is the Matrix4value model. To develop a funding decision-support tool combining MCDA and mini-HTA, based on Matrix4value, suitable for medical devices for individual patient use in French university hospitals - known as the IDA tool, short for 'innovative device assessment'. Criteria for assessing medical devices were identified from a literature review and a survey of 18 French university hospitals. Weights for the criteria, representing their relative importance, were derived from a survey of 25 members of a medical devices committee using an elicitation technique involving pairwise comparisons. As a test of its usefulness, the IDA tool was applied to two new drug-eluting beads (DEBs) for transcatheter arterial chemoembolization. The IDA tool comprises five criteria and weights for each of two over-arching categories: risk and value. The tool revealed that the two new DEBs conferred no additional value relative to DEBs currently available. Feedback from participating decision-makers about the IDA tool was very positive. The tool could help to promote a more structured and transparent approach to HTA decision-making in French university hospitals. Copyright © 2015 Elsevier Inc. All rights reserved.

  2. Relationship between severity of depression symptoms and iron deficiency anemia in women with major depressive disorder

    Directory of Open Access Journals (Sweden)

    Seyed gholamreza Noorazar

    2015-11-01

    Full Text Available Introduction: Iron deficiency (ID is a common nutritional problem lead to many unintended consequences such as decrease energy, immune system problems, and neurological dysfunction. The most common psychological disorder is depression. A patient with ID anemia (IDA show signs and symptoms of behavioral and mood disorders like depression. Methods: In this study, 100 female patients with diagnosed major depression in years 2010 and 2011 were studied. In all patients standard Hamilton depression rating scale (HDRS was used to evaluate depression severity. Blood samples were taken for complete blood count difference analysis and evaluating anemia and in those with hemoglobin (Hb < 12 mg/dl, ferritin, and total iron binding capacity were checked to evaluate IDA. Results: Patients mean age was 36.34 ± 10.43 years old. Mean HDRS score was 32.20 ± 4.07. 19 had anemia, and among them 8% had IDA. Mean HDRS score in patients with IDA (33.37 ± 1.90 was higher than those without (32.09 ± 4.19, but the difference was not significant (P = 0.39. There was no difference between patients with and without anemia in HDRS score. The negative relation was observed between Hb levels, and HDRS score (Pearson correlation = -0.21, P = 0.03. Conclusion: We observed that the negative correlation between Hb levels and HDRS score. It demonstrates the effect of Hb decrease and anemia occurrence on depression severity; however, it needs more studies.

  3. Iron deficiency, anemia, and mortality in renal transplant recipients.

    Science.gov (United States)

    Eisenga, Michele F; Minović, Isidor; Berger, Stefan P; Kootstra-Ros, Jenny E; van den Berg, Else; Riphagen, Ineke J; Navis, Gerjan; van der Meer, Peter; Bakker, Stephan J L; Gaillard, Carlo A J M

    2016-11-01

    Anemia, iron deficiency anemia (IDA), and iron deficiency (ID) are highly prevalent in renal transplant recipients (RTR). Anemia is associated with poor outcome, but the role of ID is unknown. Therefore, we aimed to investigate the association of ID, irrespective of anemia, with all-cause mortality in RTR. Cox regression analyses were used to investigate prospective associations. In 700 RTR, prevalences of anemia, IDA, and ID were 34%, 13%, and 30%, respectively. During follow-up for 3.1 (2.7-3.9) years, 81 (12%) RTR died. In univariable analysis, anemia [HR, 1.72 (95%CI: 1.11-2.66), P = 0.02], IDA [2.44 (1.48-4.01), P anemia with mortality became weaker after adjustment for ID [1.52 (0.97-2.39), P = 0.07] and disappeared after adjustment for proteinuria and eGFR [1.09 (0.67-1.78), P = 0.73]. The association of IDA with mortality attenuated after adjustment for potential confounders. In contrast, the association of ID with mortality remained independent of potential confounders, including anemia [1.77 (1.13-2.78), P = 0.01]. In conclusion, ID is highly prevalent among RTR and is associated with an increased risk of mortality, independent of anemia. As ID is a modifiable factor, correction of ID could be a target to improve survival. © 2016 The Authors. Transplant International published by John Wiley & Sons Ltd on behalf of Steunstichting ESOT.

  4. Poly(glycidyl methacrylate) beads embedded cryogels for pseudo-specific affinity depletion of albumin and immunoglobulin G

    Energy Technology Data Exchange (ETDEWEB)

    Bereli, Nilay; Sener, Guelsu; Altintas, Evrim Banu; Yavuz, Handan [Department of Chemistry, Biochemistry Division, Hacettepe University, Ankara (Turkey); Denizli, Adil, E-mail: denizli@hacettepe.edu.tr [Department of Chemistry, Biochemistry Division, Hacettepe University, Ankara (Turkey)

    2010-01-30

    Depletion of high abundant proteins like albumin and immunoglobulin G (IgG) can be beneficial in the analysis of serum proteins. For this purpose, Cibacron Blue F3GA and iminodiacetic acid (IDA)-Cu{sup 2+} containing poly(glycidyl methacrylate) (PGMA) beads (1.6 {mu}m in diameter) were embedded into the poly(hydroxyethyl methacrylate) (PHEMA) cryogel. The PGMA beads were prepared by dispersion polymerization. The PGMA beads were modified with Cibacron Blue F3GA and iminodiacetic acid (IDA)-Cu{sup 2+} for simultaneous albumin and IgG depletion, respectively. The PHEMA cryogel was synthesized by free radical polymerization in the presence of the modified PGMA beads. The PHEMA and PHEMA/PGMA composite cryogels were characterized by swelling measurements and scanning electron microscopy (SEM). Protein depletion studies were carried out in a continuous experimental set-up in a stacked column. Albumin adsorption capacity of the PGMA-Cibacron Blue F3GA beads embedded PHEMA cryogel (PHEMA/PGMA-Cibacron Blue F3GA) was 342 mg/g and IgG adsorption capacity of the PGMA-IDA-Cu{sup 2+} beads embedded PHEMA cryogel (PHEMA/PGMA-IDA-Cu{sup 2+}) was 257 mg/g. The composite cryogels depleted albumin and IgG from human serum with 89.4% and 93.6% efficiency, respectively. High desorption values (over 90% for both modified cryogels) were achieved with 0.05 M phosphate buffer containing1.0 M NaCl.

  5. Luxación traumática anterior de prótesis total de rodilla

    OpenAIRE

    Hernández Hermoso, José Antonio; Corral Munar, A.; Jimeno Urban, F.

    1998-01-01

    Se presenta un caso de luxación anterior de una prótesis total de rodilla no constreñida que conserva el ligamento cruzado posterior. Su etiopatogenia es diferente a la de las subluxaciones o luxaciones posteriores de prótesis totales de rodilla semiconstreñidas que no conservan el ligamento cruzado posterior. La reducción de la misma se consiguió sin dificultad bajo anestesia general. A pesar de la laxitud residual existente tras el tratamiento conservador, el resultado funcional después de ...

  6. Kas president ikka tõesti eksis? / Hillar Padu

    Index Scriptorium Estoniae

    Padu, Hillar

    2008-01-01

    President Toomas Hendrik Ilvese esinemisest Hantõ-Mansiiskis soome-ugri rahvaste maailmakongressil. Autor on seisukohal, et parteiline kriitika president T. H. Ilvese aadressil tunnistab, et demokraatiale pole Eestis ohtu, nagu on mõnel pool mujal Ida-Euroopas. Ungari filosoofi Gaspar Miklos Tamasi artiklist "Tänapäeva Ida-Euroopa". Lisatud karikatuur. Ilmunud ka: Meie Maa : Saarte Suvenädal 11. juuli 2008, lk. 10, pealk.: Kas president Ilves astus ämbrisse?; Meie Maa : Saarte Suvenädal 18. juuli 2008, lk. 10, pealk.: President ei astunud ämbrisse!

  7. Numerical analysis of the potential of using light radiant ceilings in combination with diffuse ventilation to achieve thermal comfort in NZEB buildings

    DEFF Research Database (Denmark)

    Krusaa, Marie Rugholm; Hviid, Christian Anker; Kolarik, Jakub

    ceiling panels. These panels make it possible to combine the heating/cooling ceiling with the diffuse ventilation method. The diffuse ventilation method or leak ventilation use larger surfaces to provide air into the room instead of diffusers. An office building is investigated an analysed on an annual...... basis in the dynamic building simulation tool IDA Indoor Climate and Energy (IDA ICE). The office building contains both offices and meeting rooms. Worst-case scenarios are investigated in the office building considering heat gains, solar gains and the temperature offset between supply water temperature...

  8. Kas Eesti avastamine algab Põhja-Eestist? : Põhja-Eesti V turismikonverents

    Index Scriptorium Estoniae

    2010-01-01

    17. novembril Jõhvi Kontserdimajas toimunud Põhja-Eesti V turismikonverentsist “Kas Eesti avastamine algab Põhja- Eestist?", mille avas Ida-Virumaa maavalitsuse Arengu- ja planeeringuosakonna juhataja Urmas Majaääs. Ülevaade SA Ida-Virumaa Ettevõtluskeskuse turismikoordinaatori Sigrid Karoni, Estonian Airi asepresidendi kommertsalal Rauno Parrase, EASi koordinaatori turismiuuringute alal Piret Kallase, kommunikatsioonikonsultandi Raul Rebase, SA Põhja-Eesti Turism projektijuhi Erika Pääbuse ja nõukogu liikme Moonika Sooneste, CityBike OÜ tegevjuhi Toomas Lelovi, Narva-Jõesuu linnapea Andres Noormägi, Loodusturismi arendaja ja koolitaja Rein Kuresoo ettekannetest

  9. Climate Change: Issues in the Science and Its Use

    Science.gov (United States)

    2009-07-01

    Thomas Lovejoy , Mr. Stuart Eizenstat, and Ms. Stephanie Meeks. Hearing...I N S T I T U T E F O R D E F E N S E A N A LY S E S IDA Document D-3904 Log: H 09-000863 July 2009 Climate Change: Issues in the Science and...challenges. I N S T I T U T E F O R D E F E N S E A N A LY S E S IDA Document D-3904 Climate Change: Issues in the Science and Its Use

  10. Coulomb couplings in solubilised light harvesting complex II (LHCII): challenging the ideal dipole approximation from TDDFT calculations.

    Science.gov (United States)

    López-Tarifa, P; Liguori, Nicoletta; van den Heuvel, Naudin; Croce, Roberta; Visscher, Lucas

    2017-07-19

    The light harvesting complex II (LHCII), is a pigment-protein complex responsible for most of the light harvesting in plants. LHCII harvests sunlight and transfers excitation energy to the reaction centre of the photo-system, where the water oxidation process takes place. The energetics of LHCII can be modulated by means of conformational changes allowing a switch from a harvesting to a quenched state. In this state, the excitation energy is no longer transferred but converted into thermal energy to prevent photooxidation. Based on molecular dynamics simulations at the microsecond time scale, we have recently proposed that the switch between different fluorescent states can be probed by correlating shifts in the chromophore-chromophore Coulomb interactions to particular protein movements. However, these findings are based upon calculations in the ideal point dipole approximation (IDA) where the Coulomb couplings are simplified as first order dipole-dipole interactions, also assuming that the chromophore transition dipole moments lay in particular directions of space with constant moduli (FIX-IDA). In this work, we challenge this approximation using the time-dependent density functional theory (TDDFT) combined with the frozen density embedding (FDE) approach. Our aim is to establish up to which limit FIX-IDA can be applied and which chromophore types are better described under this approximation. For that purpose, we use the classical trajectories of solubilised light harvesting complex II (LHCII) we have recently reported [Liguori et al., Sci. Rep., 2015, 5, 15661] and selected three pairs of chromophores containing chlorophyll and carotenoids (Chl and Car): Chla611-Chla612, Chlb606-Chlb607 and Chla612-Lut620. Using the FDE in the Tamm-Dancoff approximation (FDEc-TDA), we show that IDA is accurate enough for predicting Chl-Chl Coulomb couplings. However, the FIX-IDA largely overestimates Chl-Car interactions mainly because the transition dipole for the Cars is not

  11. Helicobacter pylori infection and low dietary iron alter behavior, induce iron deficiency anemia, and modulate hippocampal gene expression in female C57BL/6 mice.

    Directory of Open Access Journals (Sweden)

    Monika Burns

    Full Text Available Helicobacter pylori (H.pylori, a bacterial pathogen, is a causative agent of gastritis and peptic ulcer disease and is a strong risk factor for development of gastric cancer. Environmental conditions, such as poor dietary iron resulting in iron deficiency anemia (IDA, enhance H.pylori virulence and increases risk for gastric cancer. IDA affects billions of people worldwide, and there is considerable overlap between regions of high IDA and high H.pylori prevalence. The primary aims of our study were to evaluate the effect of H.pylori infection on behavior, iron metabolism, red blood cell indices, and behavioral outcomes following comorbid H. pylori infection and dietary iron deficiency in a mouse model. C57BL/6 female mice (n = 40 were used; half were placed on a moderately iron deficient (ID diet immediately post-weaning, and the other half were maintained on an iron replete (IR diet. Half were dosed with H.pylori SS1 at 5 weeks of age, and the remaining mice were sham-dosed. There were 4 study groups: a control group (-Hp, IR diet as well as 3 experimental groups (-Hp, ID diet; +Hp, IR diet; +Hp,ID diet. All mice were tested in an open field apparatus at 8 weeks postinfection. Independent of dietary iron status, H.pylori -infected mice performed fewer exploratory behaviors in the open field chamber than uninfected mice (p<0.001. Hippocampal gene expression of myelination markers and dopamine receptor 1 was significantly downregulated in mice on an ID diet (both p<0.05, independent of infection status. At 12 months postinfection, hematocrit (Hct and hemoglobin (Hgb concentration were significantly lower in +Hp, ID diet mice compared to all other study groups. H.pylori infection caused IDA in mice maintained on a marginal iron diet. The mouse model developed in this study is a useful model to study the neurologic, behavioral, and hematologic impact of the common human co-morbidity of H. pylori infection and IDA.

  12. LMDI decomposition approach: A guide for implementation

    International Nuclear Information System (INIS)

    Ang, B.W.

    2015-01-01

    Since it was first used by researchers to analyze industrial electricity consumption in the early 1980s, index decomposition analysis (IDA) has been widely adopted in energy and emission studies. Lately its use as the analytical component of accounting frameworks for tracking economy-wide energy efficiency trends has attracted considerable attention and interest among policy makers. The last comprehensive literature review of IDA was reported in 2000 which is some years back. After giving an update and presenting the key trends in the last 15 years, this study focuses on the implementation issues of the logarithmic mean Divisia index (LMDI) decomposition methods in view of their dominance in IDA in recent years. Eight LMDI models are presented and their origin, decomposition formulae, and strengths and weaknesses are summarized. Guidelines on the choice among these models are provided to assist users in implementation. - Highlights: • Guidelines for implementing LMDI decomposition approach are provided. • Eight LMDI decomposition models are summarized and compared. • The development of the LMDI decomposition approach is presented. • The latest developments of index decomposition analysis are briefly reviewed.

  13. Can soluble transferrin receptor be used in diagnosing iron deficiency anemia and assessing iron response in infants with moderate acute malnutrition?

    Science.gov (United States)

    Büyükkaragöz, Bahar; Akgun, Necat A; Bulus, Ayse D; Durmus Aydogdu, Sultan; Bal, Cengiz

    2017-04-01

    To evaluate the efficacy of soluble transferrin receptor (sTfR) in diagnosing iron deficiency anemia (IDA) and evaluating iron response in infants with moderate acute malnutrition (MAM). Infants with hemoglobin (Hb) levels lower than threshold values for anemia for their ages and hypochromic/ microcytic anemia on peripheral smear were recruited. MAM was defined as weight/height z score iron parameters and sTfR were compared among 41 infants with MAM and anemia (MA group), 32 infants with anemia without MAM (group A), and healthy controls (n= 30). Following anemia and malnutrition treatment, tests were repeated. Besides hematological indices compatible with IDA, serum iron (Fe) and transferrin saturation (TS) were significantly lower, while transferrin was significantly higher in MA and A groups compared to controls (p 0.05) and significantly higher than controls (p iron treatment, sTfR decreased in both MA and A groups (p iron treatment, we believe that this parameter was not influenced by MAM or inflammation; and it alone can be used to detect IDA and monitor treatment response in infants with MAM.

  14. Impact on infants' cognitive development of antenatal exposure to iron deficiency disorder and common mental disorders.

    Science.gov (United States)

    Tran, Thach Duc; Biggs, Beverley-Ann; Tran, Tuan; Simpson, Julie Anne; Hanieh, Sarah; Dwyer, Terence; Fisher, Jane

    2013-01-01

    The aim of this study was to examine the effects of antenatal exposure to iron deficiency anemia (IDA) and common mental disorders (CMD) on cognitive development of 6 months old infants in a developing country. A prospective population-based study in a rural province in Vietnam, which enrolled pregnant women at 12-20 weeks gestation and followed them up with their infants until six months postpartum. Criteria for IDA were Hb cognitive development was assessed by Bayley Scales of Infant and Toddler Development, 3rd Ed. Path analyses were performed to determine the direct and indirect, partly or fully mediated, causal effects of the antenatal exposures. A total of 497 pregnant women were recruited, of those 378 women provided complete data which were included in the analyses. Statistically significant direct adverse effects of persistent antenatal IDA (estimated difference of -11.62 points; 95% CI -23.01 to -0.22) and antenatal CMD (-4.80 points; 95% CI: -9.40 to -0.20) on infant Bayley cognitive scores at six months were found. Higher birthweight, household wealth, and self-rated sufficient supply of breastmilk were associated with higher cognitive scores. Maternal age >30 years and primiparity had an indirect adverse effect on infants' Bayley cognitive scores. These findings suggest that antenatal IDA and CMD both have adverse effects on child cognitive development, which if unrecognized and unaddressed are likely to be lasting. It is crucial that both these risks are considered by policy makers, clinicians, and researchers seeking to improve child cognitive function in developing countries.

  15. Formation of Mixed-Ligand Complexes of Metals(II) with Monoamine Complexones and Amino Acids in Solution

    Science.gov (United States)

    Pyreu, D. F.; Gridchin, S. N.

    2018-05-01

    The formation of mixed-ligand complexes in the M(II)-Nta, Ida-L (M = Cu(II), Ni, Zn, Co(II), L = Ser, Thr, Asp, Arg, Asn) systems, where Ida and Nta are the residues of iminodiacetic and nitrilotriacetic acids, respectively, is studied using pH measurements, calorimetry and spectrophotometry. The thermodynamic parameters (log K, Δr G 0, Δr H, Δr S) of their formation at 298.15 K and ionic strength I = 0.5 (KNO3) are determined. The most likely scenario of amino acid residue coordination in the composition of mixed complexes is discussed.

  16. Effect of a nutrition education program and diet modification in Beninese adolescent girls suffering from mild iron deficiency anemia.

    Science.gov (United States)

    Alaofé, Halimatou; Zee, John; Dossa, Romain; O'Brien, Huguette Turgeon

    2009-01-01

    A 26-week nutrition intervention, including 4 weeks of nutrition education, combined with an increase in the content and bioavailability of dietary iron for 22 weeks was carried out in 34 intervention and 34 control adolescent girls suffering from mild iron deficiency anemia (IDA). In post-intervention, hemoglobin and serum ferritin were significantly higher in the intervention group, whereas the incidence of IDA was significantly lower in the intervention group compared to the control group. Nutrition knowledge scores were significantly higher in intervention girls compared to control girls. Dietary changes to improve available dietary iron can reduce iron deficiency anemia.

  17. 2235-IJBCS-Article-Rachelle Ida Yapo

    African Journals Online (AJOL)

    hp

    ci, Tel :(+225) 02 48 60 21. ... Les résultats des analyses physico-chimiques montrent que les eaux sont légèrement acides et faiblement minéralisées avec des valeurs de .... d'injecteur de 280 °C. Le gaz vecteur était l'hélium de haute pureté ...

  18. The 1996 IDA Cost Research Symposium.

    Science.gov (United States)

    1996-08-01

    5160 Christopher Deegan (703)602-6575 Performer: Naval Surface Warfare Center (211) Carderock Division, NSWC/CD Bethesda, Maryland 20084-5000...Moore (703) 602-0330, ext 208 Cost Engineering Research, Inc. 2011 Crystal Drive Arlington, VA 22202-3717 Bill Hugo Bob Craig Classification...Director, Force and Infrastructure Cost Analysis Division OD (PA&E) Room 2D278, The Pentagon Washington, DC 20301 Dr. Craig College LMI John Wallace

  19. IDA: An Intelligent Data Access Program

    National Research Council Canada - National Science Library

    Sagalowicz, Daniel

    1977-01-01

    .... The first component of LADDER is INLAND (Informal Natural Language Access to Navy Data), which allows the user to ask questions in English about information contained in databases similar to those currently...

  20. The 1997 IDA Cost Research Symposium.

    Science.gov (United States)

    1997-07-01

    AMCOS) CEAC-3 ACEIT /ACDB CEAC-4 Communications and Electronics Cost Model/Methodology CEAC-5 Operating and Support Management Information System...AFCAA-40 ACDB Upgrades (FY 98) AFCAA-41 ACEIT Upgrades (FY 97 and out) Air Force Materiel Command/Aeronautical Systems Center ASC/FMC-1 Acquisition...Civilian Manpower Reduction Model. The Cost Factor Handbook will be linked to ACEIT to improve cost analysts access to the data. Unclassified US

  1. Ida-igatsuse põhjapiir / Raivo Paltser

    Index Scriptorium Estoniae

    Paltser, Raivo

    2006-01-01

    Hiina traditsiooni järgija R. Paltseri nägemus Lääne inimese ihalusest Vana-Hiina kultuuri järele, kung-fust. Toodud mõningaid näiteid Soome ja Hiina mütoloogiat ühendavast fantaasiafilmist "Igavese armastuse sõdalane - Jade Warrior"

  2. Purification of yeast alcohol dehydrogenase by using immobilized metal affinity cryogels

    International Nuclear Information System (INIS)

    Akduman, Begüm; Uygun, Murat; Uygun, Deniz Aktaş; Akgöl, Sinan; Denizli, Adil

    2013-01-01

    In this study, poly(2-hydroxyethyl methacrylate–glycidylmethacrylate) [poly(HEMA–GMA)] cryogels were prepared by radical cryocopolymerization of HEMA with GMA as a functional comonomer and N,N′-methylene-bisacrylamide (MBAAm) as a crosslinker. Iminodiacetic acid (IDA) functional groups were attached via ring opening of the epoxy group on the poly(HEMA–GMA) cryogels and then Zn(II) ions were chelated with these structures. Characterization of cryogels was performed by FTIR, SEM, EDX and swelling studies. These cryogels have interconnected pores of 30–50 μm size. The equilibrium swelling degree of Zn(II) chelated poly(HEMA–GMA)-IDA cryogels was approximately 600%. Zn(II) chelated poly(HEMA–GMA)-IDA cryogels were used in the adsorption of alcohol dehydrogenase from aqueous solutions and adsorption was performed in continuous system. The effects of pH, alcohol dehydrogenase concentration, temperature, and flow rate on adsorption were investigated. The maximum amount of alcohol dehydrogenase adsorption was determined to be 9.94 mg/g cryogel at 1.0 mg/mL alcohol dehydrogenase concentration and in acetate buffer at pH 5.0 with a flow rate of 0.5 mL/min. Desorption of adsorbed alcohol dehydrogenase was carried out by using 1.0 M NaCI at pH 8.0 phosphate buffer and desorption yield was found to be 93.5%. Additionally, these cryogels were used for purification of alcohol dehydrogenase from yeast with a single-step. The purity of desorbed alcohol dehydrogenase was shown by silver-stained SDS–PAGE. This purification process can successfully be used for the purification of alcohol dehydrogenase from unclarified yeast homogenates and this work is the first report about the usage of the cryogels for purification of alcohol dehydrogenase. - Highlights: • Poly(HEMA–GMA) cryogels were synthesized by radical cryocopolymerization technique. • Prepared cryogels were functionalized with IDA, then Zn(II) ions were chelated to the cryogel. • Zn(II) chelated poly(HEMA–GMA)-IDA

  3. Purification of yeast alcohol dehydrogenase by using immobilized metal affinity cryogels

    Energy Technology Data Exchange (ETDEWEB)

    Akduman, Begüm [Chemistry Department, Adnan Menderes University, Aydın (Turkey); Uygun, Murat [Koçarlı Vocational and Training School, Adnan Menderes University, Aydın (Turkey); Uygun, Deniz Aktaş, E-mail: daktas@adu.edu.tr [Chemistry Department, Adnan Menderes University, Aydın (Turkey); Akgöl, Sinan [Biochemistry Department, Ege University, İzmir (Turkey); Denizli, Adil [Chemistry Department, Hacettepe University, Ankara (Turkey)

    2013-12-01

    In this study, poly(2-hydroxyethyl methacrylate–glycidylmethacrylate) [poly(HEMA–GMA)] cryogels were prepared by radical cryocopolymerization of HEMA with GMA as a functional comonomer and N,N′-methylene-bisacrylamide (MBAAm) as a crosslinker. Iminodiacetic acid (IDA) functional groups were attached via ring opening of the epoxy group on the poly(HEMA–GMA) cryogels and then Zn(II) ions were chelated with these structures. Characterization of cryogels was performed by FTIR, SEM, EDX and swelling studies. These cryogels have interconnected pores of 30–50 μm size. The equilibrium swelling degree of Zn(II) chelated poly(HEMA–GMA)-IDA cryogels was approximately 600%. Zn(II) chelated poly(HEMA–GMA)-IDA cryogels were used in the adsorption of alcohol dehydrogenase from aqueous solutions and adsorption was performed in continuous system. The effects of pH, alcohol dehydrogenase concentration, temperature, and flow rate on adsorption were investigated. The maximum amount of alcohol dehydrogenase adsorption was determined to be 9.94 mg/g cryogel at 1.0 mg/mL alcohol dehydrogenase concentration and in acetate buffer at pH 5.0 with a flow rate of 0.5 mL/min. Desorption of adsorbed alcohol dehydrogenase was carried out by using 1.0 M NaCI at pH 8.0 phosphate buffer and desorption yield was found to be 93.5%. Additionally, these cryogels were used for purification of alcohol dehydrogenase from yeast with a single-step. The purity of desorbed alcohol dehydrogenase was shown by silver-stained SDS–PAGE. This purification process can successfully be used for the purification of alcohol dehydrogenase from unclarified yeast homogenates and this work is the first report about the usage of the cryogels for purification of alcohol dehydrogenase. - Highlights: • Poly(HEMA–GMA) cryogels were synthesized by radical cryocopolymerization technique. • Prepared cryogels were functionalized with IDA, then Zn(II) ions were chelated to the cryogel. • Zn(II) chelated poly(HEMA–GMA)-IDA

  4. Impact on Infants’ Cognitive Development of Antenatal Exposure to Iron Deficiency Disorder and Common Mental Disorders

    Science.gov (United States)

    Tran, Thach Duc; Biggs, Beverley-Ann; Tran, Tuan; Simpson, Julie Anne; Hanieh, Sarah; Dwyer, Terence; Fisher, Jane

    2013-01-01

    Objectives The aim of this study was to examine the effects of antenatal exposure to iron deficiency anemia (IDA) and common mental disorders (CMD) on cognitive development of 6 months old infants in a developing country. Methods A prospective population-based study in a rural province in Vietnam, which enrolled pregnant women at 12–20 weeks gestation and followed them up with their infants until six months postpartum. Criteria for IDA were Hb cognitive development was assessed by Bayley Scales of Infant and Toddler Development, 3rd Ed. Path analyses were performed to determine the direct and indirect, partly or fully mediated, causal effects of the antenatal exposures. Results A total of 497 pregnant women were recruited, of those 378 women provided complete data which were included in the analyses. Statistically significant direct adverse effects of persistent antenatal IDA (estimated difference of −11.62 points; 95% CI −23.01 to −0.22) and antenatal CMD (−4.80 points; 95% CI: −9.40 to −0.20) on infant Bayley cognitive scores at six months were found. Higher birthweight, household wealth, and self-rated sufficient supply of breastmilk were associated with higher cognitive scores. Maternal age >30 years and primiparity had an indirect adverse effect on infants’ Bayley cognitive scores. Conclusions These findings suggest that antenatal IDA and CMD both have adverse effects on child cognitive development, which if unrecognized and unaddressed are likely to be lasting. It is crucial that both these risks are considered by policy makers, clinicians, and researchers seeking to improve child cognitive function in developing countries. PMID:24086390

  5. Assessment of subjective sleep quality in iron deficiency anaemia.

    Science.gov (United States)

    Murat, Semiz; Ali, Uslu; Serdal, Korkmaz; Süleyman, Demir; İlknur, Parlak; Mehmet, Sencan; Bahattin, Aydın; Tunahan, Uncu

    2015-06-01

    We aimed to assess the effect of anemia on subjective sleep quality in patients with iron deficiency anemia (IDA). One hundred and four patients diagnosed with IDA and 80 healthy individuals, who are gender and age matched, were included in the study. All participants were requested to fill 3 forms: a socio-demographic form (age, gender, marital status, income level and educational status), hospital anxiety and depression (HAD) scale and pittsburgh sleep quality index (PSQI). According to the HAD scale, the average anxiety score was found 9.24±4.37 in patients and 7.58± 4.07 in controls. And, the average depression score was 7.53±4.10 in patients and 6.41±2.74 in controls. The total sleep quality score was 6.71±3.02 in patients and 4.11±1.64 in controls. There was a statistically significant difference in terms of anxiety, depression and sleep quality scores. Linear regression analysis showed no association between anxiety and depression with poor sleeping. IDA affects sleep quality irrespective of psychological symptoms such as depression and anxiety.

  6. Stability constant determinations for technetium (IV) complexation with selected amino carboxylate ligands in high nitrate solutions

    Energy Technology Data Exchange (ETDEWEB)

    Omoto, Trevor; Wall, Nathalie A. [Washington State Univ., Pullman, WA (United States). Dept. of Chemistry

    2017-10-01

    The stability constants for Tc(IV) complexation with the ligands IDA, NTA, HEDTA, and DTPA were determined in varied nitrate concentrations using liquid-liquid extraction methods. The determined log β{sub 101} stability constants at 0.5 M NaNO{sub 3} were found to be 9.2±0.3, 10.3±0.3, and 15.3±0.3 for IDA, NTA, and HEDTA, respectively. The log β{sub 111} stability constant for DTPA was determined to be 22.0±0.6. These determined stability constants show a slight decrease in magnitude as a function of increasing NaNO{sub 3} concentration. These stability constants were used to model the total dissolution of Tc(IV) in acidic aqueous solutions in the presence of each ligand. The results of these predictive models indicate that amino carboxylic ligands have a high potential for increasing the aqueous dissolution of Tc(IV); at pH 2.3, 0.01 M ligand yield dissolved Tc(IV) concentrations of 1.42.10{sup -5} M, 1.33.10{sup -5} M, 6.07.10{sup -6} M, 9.65.10{sup -7} M, for DTPA, HEDTA, NTA, and IDA, respectively.

  7. Development of cogeneration in Spain and financing methods

    International Nuclear Information System (INIS)

    Garcia, G.R.

    1994-01-01

    From 1980 there is in force in Spain a proper legal framework that could be considered a sound support to further cogeneration development. Despite this cogeneration law, a very few schemes were built. In 1986 IDAE, a state company attached to the Spanish Ministry of Industry and Energy, began a Cogeneration Programme focussed to a higher cogeneration utilisation. This programme has three main foundations: Technology dissemination; Technical support; Investment financing. As a result of these activities more than 1000 MW additional power schemes have been ordered all over the country and, as a consequence, cogenerated electricity will be multiplied by three in respect with the previous situation. A 20% of this new capacity has been developed directly by IDAE, that has invested approximately 90 million US Dollar through third party financing technics. The National Energy Plan 1991-2000 established the energy policy actuations in Spain for the present decade, giving importance to cogeneration development. This paper explains the way this development has been achieved, outlining IDAE's engagement to finance combined heat and power schemes through its comprehensive way of performing third party financing systems. (au)

  8. Direct protein detection with a nano-interdigitated array gate MOSFET.

    Science.gov (United States)

    Tang, Xiaohui; Jonas, Alain M; Nysten, Bernard; Demoustier-Champagne, Sophie; Blondeau, Franoise; Prévot, Pierre-Paul; Pampin, Rémi; Godfroid, Edmond; Iñiguez, Benjamin; Colinge, Jean-Pierre; Raskin, Jean-Pierre; Flandre, Denis; Bayot, Vincent

    2009-08-15

    A new protein sensor is demonstrated by replacing the gate of a metal oxide semiconductor field effect transistor (MOSFET) with a nano-interdigitated array (nIDA). The sensor is able to detect the binding reaction of a typical antibody Ixodes ricinus immunosuppressor (anti-Iris) protein at a concentration lower than 1 ng/ml. The sensor exhibits a high selectivity and reproducible specific detection. We provide a simple model that describes the behavior of the sensor and explains the origin of its high sensitivity. The simulated and experimental results indicate that the drain current of nIDA-gate MOSFET sensor is significantly increased with the successive binding of the thiol layer, Iris and anti-Iris protein layers. It is found that the sensor detection limit can be improved by well optimizing the geometrical parameters of nIDA-gate MOSFET. This nanobiosensor, with real-time and label-free capabilities, can easily be used for the detection of other proteins, DNA, virus and cancer markers. Moreover, an on-chip associated electronics nearby the sensor can be integrated since its fabrication is compatible with complementary metal oxide semiconductor (CMOS) technology.

  9. Lymphocyte DNA damage and oxidative stress in patients with iron deficiency anemia.

    Science.gov (United States)

    Aslan, Mehmet; Horoz, Mehmet; Kocyigit, Abdurrahim; Ozgonül, Saadet; Celik, Hakim; Celik, Metin; Erel, Ozcan

    2006-10-10

    Oxidant stress has been shown to play an important role in the pathogenesis of iron deficiency anemia. The aim of this study was to investigate the association between lymphocyte DNA damage, total antioxidant capacity and the degree of anemia in patients with iron deficiency anemia. Twenty-two female with iron deficiency anemia and 22 healthy females were enrolled in the study. Peripheral DNA damage was assessed using alkaline comet assay and plasma total antioxidant capacity was determined using an automated measurement method. Lymphocyte DNA damage of patients with iron deficiency anemia was significantly higher than controls (ptotal antioxidant capacity was significantly lower (ptotal antioxidant capacity and hemoglobin levels (r=0.706, ptotal antioxidant capacity and hemoglobin levels were negatively correlated with DNA damage (r=-0.330, p<0.05 and r=-0.323, p<0.05, respectively). In conclusion, both oxidative stress and DNA damage are increased in IDA patients. Increased oxidative stress seems as an important factor that inducing DNA damage in those IDA patients. The relationships of oxidative stress and DNA damage with the severity of anemia suggest that both oxidative stress and DNA damage may, in part, have a role in the pathogenesis of IDA.

  10. Psychological and social factors associated with late pregnancy iron deficiency anaemia in rural Viet Nam: a population-based prospective study.

    Science.gov (United States)

    Tran, Thach Duc; Biggs, Beverley-Ann; Tran, Tuan; Casey, Gerard J; Hanieh, Sarah; Simpson, Julie Anne; Dwyer, Terence; Fisher, Jane

    2013-01-01

    The aim of this study was to examine the relationships between psychological and social factors and late pregnancy IDA among pregnant women in rural Viet Nam. Pregnant women from 50 randomly-selected communes within Ha Nam province were recruited and assessed at 12 - 20 weeks gestation (Wave 1, W1). They were followed up in the last trimester (Wave 2, W2). IDA was defined as Haemoglobin Viet Nam. The link between them suggests that while direct recommendations to use iron supplements are important, the social factors associated with common mental disorders should be addressed in antenatal care in order to improve the health of pregnant women and their infants.

  11. Svobodnõi tshelovek v osoboi zone / Tunne Kelam ; interv. J. Ashihmin

    Index Scriptorium Estoniae

    Kelam, Tunne, 1936-

    2000-01-01

    Narva Kolledzhis toimus Riigikogu infopäev. Ida-Virumaa hetkeolukord, integratsiooniprotsess, kodakondsus- ja migratsiooniameti töö endiselt halvasti organiseeritud. Autor: Isamaaliit. Parlamendisaadik

  12. Maakonna arengukavas pole omavalitsuste häält kuulda / Urve Erikson

    Index Scriptorium Estoniae

    Erikson, Urve, 1956-

    2005-01-01

    Ilmunud ka: Severnoje Poberezhje 20. jaan., lk. 2. Ida-Virumaa omavalitsuste liidu tegevdirektor peab oluliseks kohalike omavalitsuste osalemist ning avalikku arutelu maakonna arengustrateegia koostamisel

  13. Euroopa tulevikuvisiooni näeme Ceutas ja Melillas / Daniel Pipes ; intervjueerinud Taavi Minnik

    Index Scriptorium Estoniae

    Pipes, Daniel

    2016-01-01

    Intervjuu Lähis-Ida Foorumi presidendi Daniel Pipesiga Euroopa migratsioonikriisist ja vigadest migratsioonipoliitikas. Probleemidest, mida massiimmigratsioon Kolmandast Maailmast Euroopale kaasa toob ning radikaalse islami ohtudest

  14. Iron status of toddlers, nonpregnant females, and pregnant females in the United States.

    Science.gov (United States)

    Gupta, Priya M; Hamner, Heather C; Suchdev, Parminder S; Flores-Ayala, Rafael; Mei, Zuguo

    2017-12-01

    Background: Total-body iron stores (TBI), which are calculated from serum ferritin and soluble transferrin receptor concentrations, can be used to assess the iron status of populations in the United States. Objective: This analysis, developed to support workshop discussions, describes the distribution of TBI and the prevalence of iron deficiency (ID) and ID anemia (IDA) among toddlers, nonpregnant females, and pregnant females. Design: We analyzed data from NHANES; toddlers aged 12-23 mo (NHANES 2003-2010), nonpregnant females aged 15-49 y (NHANES 2007-2010), and pregnant females aged 12-49 y (NHANES 1999-2010). We used SAS survey procedures to plot distributions of TBI and produce prevalence estimates of ID and IDA for each target population. All analyses were weighted to account for the complex survey design. Results: According to these data, ID prevalences (± SEs) were 15.1% ± 1.7%, 10.4% ± 0.5%, and 16.3% ± 1.3% in toddlers, nonpregnant females, and pregnant females, respectively. ID prevalence in pregnant females increased significantly with each trimester (5.3% ± 1.5%, 12.7% ± 2.3%, and 27.5% ± 3.5% in the first, second, and third trimesters, respectively). Racial disparities in the prevalence of ID among both nonpregnant and pregnant females exist, with Mexican American and non-Hispanic black females at greater risk of ID than non-Hispanic white females. IDA prevalence was 5.0% ± 0.4% and 2.6% ± 0.7% in nonpregnant and pregnant females, respectively. Conclusions: Available nationally representative data suggest that ID and IDA remain a concern in the United States. Estimates of iron-replete status cannot be made at this time in the absence of established cutoffs for iron repletion based on TBI. The study was registered at clinicaltrials.gov as NCT03274726. © 2017 American Society for Nutrition.

  15. Iron status in pregnant women and women of reproductive age in Europe.

    Science.gov (United States)

    Milman, Nils; Taylor, Christine L; Merkel, Joyce; Brannon, Patsy M

    2017-12-01

    Understanding the iron status in pregnant women in Europe provides a foundation for considering the role of iron screening and supplementation. However, available reports and studies have used different approaches that challenge the devising of overall summaries. Moreover, data on pregnant women are limited, and thus, data on women of reproductive age provide useful background information including baseline iron stores in pregnant women. This review considered data that are available from >15 European countries including national surveys and relevant clinical studies. In European women of reproductive age, median or geometric mean serum ferritin (SF) concentrations were estimated at 26-38 μg/L. Approximately 40-55% of this population had small or depleted iron stores (i.e., SF concentration ≤30 μg/L), and 45-60% of this population had apparently replete iron stores. The prevalence of iron deficiency (ID) and iron deficiency anemia (IDA) was 10-32% and 2-5%, respectively, depending on the cutoffs used. Approximately 20-35% of European women of reproductive age had sufficient iron stores (SF concentration >70 μg/L) to complete a pregnancy without supplementary iron. During pregnancy, European women in controlled supplementation trials who were not receiving iron supplements displayed increasing prevalences of ID and IDA during pregnancy, which peaked in the middle to late third trimester. Available evidence has suggested that, in gestational weeks 32-39, the median or geometric mean SF concentrations were 6-21 μg/L, and prevalences of ID and IDA were 28-85% and 21-35%, respectively. Women who were taking iron supplements had higher iron status and lower prevalences of ID and IDA, which were dependent on the dose of iron and compliance. The data suggest that, in Europe, the iron status of reproductive-aged women varies by region and worsens in pregnancy without iron supplementation. © 2017 American Society for Nutrition.

  16. Diagnosis of iron deficiency anemia using density-based fractionation of red blood cells.

    Science.gov (United States)

    Hennek, Jonathan W; Kumar, Ashok A; Wiltschko, Alex B; Patton, Matthew R; Lee, Si Yi Ryan; Brugnara, Carlo; Adams, Ryan P; Whitesides, George M

    2016-10-05

    Iron deficiency anemia (IDA) is a nutritional disorder that impacts over one billion people worldwide; it may cause permanent cognitive impairment in children, fatigue in adults, and suboptimal outcomes in pregnancy. IDA can be diagnosed by detection of red blood cells (RBCs) that are characteristically small (microcytic) and deficient in hemoglobin (hypochromic), typically by examining the results of a complete blood count performed by a hematology analyzer. These instruments are expensive, not portable, and require trained personnel; they are, therefore, unavailable in many low-resource settings. This paper describes a low-cost and rapid method to diagnose IDA using aqueous multiphase systems (AMPS)-thermodynamically stable mixtures of biocompatible polymers and salt that spontaneously form discrete layers having sharp steps in density. AMPS are preloaded into a microhematocrit tube and used with a drop of blood from a fingerstick. After only two minutes in a low-cost centrifuge, the tests (n = 152) were read by eye with a sensitivity of 84% (72-93%) and a specificity of 78% (68-86%), corresponding to an area under the curve (AUC) of 0.89. The AMPS test outperforms diagnosis by hemoglobin alone (AUC = 0.73) and is comparable to methods used in clinics like reticulocyte hemoglobin concentration (AUC = 0.91). Standard machine learning tools were used to analyze images of the resulting tests captured by a standard desktop scanner to 1) slightly improve diagnosis of IDA-sensitivity of 90% (83-96%) and a specificity of 77% (64-87%), and 2) predict several important red blood cell parameters, such as mean corpuscular hemoglobin concentration. These results suggest that the use of AMPS combined with machine learning provides an approach to developing point-of-care hematology.

  17. Endoscopic investigation in non-iron deficiency anemia: a cost to the health system without patient benefit.

    Science.gov (United States)

    Mogilevski, Tamara; Smith, Rebecca; Johnson, Douglas; Charles, Patrick G P; Churilov, Leonid; Vaughan, Rhys; Ma, Ronald; Testro, Adam

    2016-02-01

    The indication for endoscopy to investigate anemia of causes other than iron deficiency is not clear. Increasing numbers of endoscopic procedures for anemia raises concerns about costs to the health system, waiting times, and patient safety. The primary aim of this study was to determine the diagnostic yield of endoscopy in patients referred to undergo investigation for anemia. Secondary aims were to identify additional factors enabling the risk stratification of those likely to benefit from endoscopic investigation, and to undertake a cost analysis of performing endoscopy in this group of patients. We performed a retrospective review of endoscopy referrals for the investigation of anemia over a 12-month period at a single center. The patients were divided into three groups: those who had true iron deficiency anemia (IDA), tissue iron deficiency without anemia (TIDWA), or anemia of other cause (AOC). Outcome measures included finding a lesion responsible for the anemia and a significant change of management as a result of endoscopy. A costing analysis was performed with an activity-based costing method. We identified 283 patients who underwent endoscopy to investigate anemia. A likely cause of anemia was found in 31 of 150 patients with IDA (21 %) and 0 patients in the other categories (P cost of a single colonoscopy or gastroscopy was approximated to be $ 2209. Endoscopic investigation for non-IDA comes at a significant cost to our institution, equating to a minimum of $ 293 797 per annum in extra costs, and does not result in a change of management in the majority of patients. No additional factors could be established to identify patients who might be more likely to benefit from endoscopic investigation. The endoscopic investigation of non-IDA should be minimized.

  18. "Predprinimatelstvo - eto neprestizhno" / Jaroslav Tolstikov

    Index Scriptorium Estoniae

    Tolstikov, Jaroslav

    2000-01-01

    Uurimus Ida-Virumaa Vene noorte hulgas "Noored muutuvas maailmas". Diagrammid: perekondade majanduslik oukord, murettekitavad probleemid, millises riigis soovitakse tulevikus töötada, suhtumine EL-i

  19. Expanding the horizon - new countries on the European the TV-landscape / Hagi Shein

    Index Scriptorium Estoniae

    Šein, Hagi, 1945-

    2005-01-01

    Siirdeperioodi arengutendentsidest Kesk- ja Ida-Euroopa televaldkonnas, Euroopa meediapoliitika põhimõtetest, eriti piiriülese televisiooni direktiivi nõuete rakendamisega seonduvast. Diagrammid. Tabelid. Graafikud. Skeemid

  20. Nutikad pildid / Art Leete

    Index Scriptorium Estoniae

    Leete, Art, 1969-

    1999-01-01

    Pärnu 13. rahvusvahelisel dokumentaal- ja antropoloogiafilmide festivalil linastunud filmidest. Lisad : Üleskutse Ida-Euroopa riikide kultuuriministritele ; XIII Pärnu rahvusvahelise dokumentaal- ja antropoloogiafilmide festivali auhinnad

  1. Eesti Energia korraldas OSELCA projekti raames Tallinnas rahvusvahelise seminari / Reigo Lehtla

    Index Scriptorium Estoniae

    Lehtla, Reigo

    2005-01-01

    Eesti Energia AS korraldas 12.-13. septembrini 2005. a. Tallinna Tehnikaülikooli energeetikahoones rahvusvahelise seminari olelusringi hindamise (Life Cycle Assessment) metoodika hetkeseisust Ida-Euroopa regioonis

  2. Ex uno plures´est e pluribus unum´ini? / Rein Müllerson ; inglise keelest tõlkinud Marek Laane

    Index Scriptorium Estoniae

    Müllerson, Rein, 1944-

    2010-01-01

    Õigusteadlane Rein Müllerson ühiskondliku mitmekesisuse ja homogeensuse arengutest, dissimilatsiooni asendumisest assimilatsiooniga, Ida ja Lääne ühiskondade ühildumisest üleilmastumise protsessis

  3. Name and shame in new regime / Fredrik Davidsson

    Index Scriptorium Estoniae

    Davidsson, Fredrik

    2010-01-01

    Euroopa Komisjon on algatanud kampaania, mille kohaselt peetakse internetis nimekirja laevandusettevõtetest, kes ei täida ohutusnõudeid. Euroopa Komisjoni transpordivolinik Siim Kallas uuest eeskirjast

  4. Omavalitsused ja hariduspoliitika / Urve Erikson

    Index Scriptorium Estoniae

    Erikson, Urve, 1956-

    2003-01-01

    Ilmunud ka: Severnoje Poberezhje 8. nov. lk. 2. Ida-Virumaa omavalitsuste liidu tegevdirektor kohalike omavalitsuste kuludest kvaliteetse hariduse tagamisel ning haridusstrateegia ja maakondlike arengukavade puudumisest Eestis

  5. EU applicants to reform justice, border systems / Janet McEvoy

    Index Scriptorium Estoniae

    McEvoy, Janet

    1998-01-01

    Euroopa Liidu siseministrite kohtumisel 30. jaanuaril 1998. a. leiti, et Ida-Euroopa riigid peavad tõhustama organiseeritud kuritegevuse ja illegaalse immigratsiooni vastaseid meetmeid enne liitumist Euroopa Liiduga

  6. Inimõigustest paberil ja tegelikult / Stuart Sweeney

    Index Scriptorium Estoniae

    Sweeney, Stuart

    2008-01-01

    Amnesty Internationali ajakirjanik vaatleb 12. PÖFFi kümnefilmilist inimõiguste programmi "Ikkagi inimene", paralleelselt toimunud konverentsi ja integratsiooniprojekti "Ida-Virumaa aruanne" (ZUGA Ühendatud Tantsijad)

  7. Constitutsionalism and credibility in reforming economies / Raj M. Desai, Anders Olofsgard

    Index Scriptorium Estoniae

    Desai, Raj M.

    2006-01-01

    Artikkel uurib põhiseaduslikkuse, poliitilise vastutuse ja sõltumatu kohtuvõimu seoseid avaliku arvamuse toetusega majandusreformidele 90-ndate aastate Kesk- ja Ida-Euroopa üleminekuriikides. Tabelid. Graafikud

  8. Cholescintigraphy

    International Nuclear Information System (INIS)

    Tjen, H.S.L.M.

    1979-01-01

    This thesis describes the clinical application of cholescintigraphy with sup(99m)Technetium-diethyl-IDA as hepato-biliary radiopharmaceutical. After a review of some anatomical and physiological properties of liver and biliary tract the conceptions jaundice and cholestasis are defined. Various clinical investigations in patients with liver and biliary tract disorders are discussed such as biochemical blood examinations, liver biopsy and radiological investigations. The applications and limitations of colloid liver scintigraphy in patients with focal or diffuse liver diseases are reviewed. Furthermore the diagnostic value of this investigation in jaundiced patients is discussed. The literature study ends with a review of the application of various hepato-biliary radiopharmaceuticals and the development, properties and first application of IDA-derivates. The synthesis, preparation and quality control of diethyl-IDA which is available as an 'instant labelling kit' (Solco-HIDAsup(R)) is described. The biological properties of the radiopharmaceutical are studied by means of kinetic and autoradiographic investigations in rat. As introduction to the clinical studies the technical basis of cholescintigraphy is described that encompasses the performance of the serial scintigrams and the generation of time-activity curves and functional images by a computer. Cholescintigraphic patterns in individuals without liver or biliary tract disorders are shown. (Auth.)

  9. Wireless capsule endoscopy and proximal small bowel lesions in Crohn’s disease

    Science.gov (United States)

    Petruzziello, Carmelina; Onali, Sara; Calabrese, Emma; Zorzi, Francesca; Ascolani, Marta; Condino, Giovanna; Lolli, Elisabetta; Naccarato, Paola; Pallone, Francesco; Biancone, Livia

    2010-01-01

    AIM: To investigate the prevalence of proximal small bowel (SB) lesions detected by wireless capsule endoscopy (WCE) in Crohn’s disease (CD). METHODS: WCE was performed in 64 patients: 32 with CD of the distal ileum, and 32 controls with iron-deficiency anemia (IDA) or diarrhea. WCE was performed using the Given SB-WCE, followed by small intestine contrast ultrasonography (SICUS). Findings compatible with CD by using WCE included erosions, aphthoid or deep ulcers, and strictures/stenosis. RESULTS: WCE detected proximal SB lesions in 16/32 (50%) patients (14 aphthoid ulcers, 2 deep ulcers, one stricture), which appeared not to be related to clinical parameters [epigastric pain, age, smoking, non-steroidal anti-inflammatory drugs (NSAIDs), IDA]. Among patients with proximal SB lesions, 6 (37%) were smokers, 3 (19%) NSAID users, 3 (19%) had epigastric pain and 4 (25%) had IDA. SICUS detected proximal SB lesions in 3/32 patients (19%) also showing lesions with WCE. No correlations were observed between proximal SB lesions assessed by WCE or by SICUS (χ2 = 1.5, P = 0.2). CONCLUSION: The use of WCE allows the detection of previously unknown upper SB lesions in a high proportion of patients with a previous diagnosis of CD involving the distal ileum. PMID:20614486

  10. Oxidation of Cu(II) aminopolycarboxylates by carbonate radical. A flash photolysis study

    International Nuclear Information System (INIS)

    Mandal, P.C.; Bardhan, D.K.

    1999-01-01

    Reactions of carbonate radical (CO 3 -. ) generated by photolysis or by radiolysis of a carbonate solution, with Cu(II) complexes of aminopolycarboxylic acids viz., Cu(II)ethylenediamine tetraacetate [Cu II EDTA] 2- and Cu(II)-iminodiacetate [Cu II IDA] were studied at pH 10.5 and ionic strength 0.2 mol x dm -3 . Time-resolved spectroscopy and kinetics for the transients were studied using flash photolysis and stable products arising from the ligand degradation of the complex were ascertained by steady-state radiolysis experiments. From the kinetic data it is observed that CO 3 -. radical reacts initially with Cu II -complex to form a transient intermediate having maximum absorption at 335 nm and 430 nm. From the subsequent reactions of this intermediate it was assigned to be Cu III .species. This Cu(III) species undergoes intermolecular electron transfer with the Cu II -complex to give a radical intermediate which again slowly reacts with Cu II -complex to give a long lived species containing Cu-C bond. This long lived species, however, slowly decomposed to give glyoxalic reaction between Cu III -complex and a suitable donor, the one electron reduction potential for [Cu III EDTA] 1- /[Cu II EDTA] 2- and [Cu III IDA] +1 /Cu II IDA was determined. (author)

  11. Incremental Dynamic Analysis of Koyna Dam under Repeated Ground Motions

    Science.gov (United States)

    Zainab Nik Azizan, Nik; Majid, Taksiah A.; Nazri, Fadzli Mohamed; Maity, Damodar; Abdullah, Junaidah

    2018-03-01

    This paper discovers the incremental dynamic analysis (IDA) of concrete gravity dam under single and repeated earthquake loadings to identify the limit state of the dam. Seven ground motions with horizontal and vertical direction as seismic input considered in the nonlinear dynamic analysis based on the real repeated earthquake in the worldwide. All the ground motions convert to respond spectrum and scaled according to the developed elastic respond spectrum in order to match the characteristic of the ground motion to the soil type. The scaled was depends on the fundamental period, T1 of the dam. The Koyna dam has been selected as a case study for the purpose of the analysis by assuming that no sliding and rigid foundation, has been estimated. IDA curves for Koyna dam developed for single and repeated ground motions and the performance level of the dam identifies. The IDA curve of repeated ground motion shown stiffer rather than single ground motion. The ultimate state displacement for a single event is 45.59mm and decreased to 39.33mm under repeated events which are decreased about 14%. This showed that the performance level of the dam based on seismic loadings depend on ground motion pattern.

  12. Oral Iron Prophylaxis in Pregnancy: Not Too Little and Not Too Much!

    Directory of Open Access Journals (Sweden)

    Nils Milman

    2012-01-01

    Full Text Available An adequate supply of iron is essential for normal development of the fetus and newborn child. Iron deficiency and iron deficiency anemia (IDA during pregnancy increase the risk of preterm birth and low birth weight. Iron is important for development of the fetal brain and cognitive abilities of the newborn. Children born to iron-deficient mothers will start their lives suffering from iron deficiency or even IDA. Oral iron prophylaxis to pregnant women improves iron status and prevents development of IDA. The Danish National Board of Health has since 1992 recommended prophylactic oral iron supplements to all pregnant women and the currently advocated dose is 40–50 mg ferrous iron taken between meals from 10 weeks gestation to delivery. However, 30–40 mg ferrous iron is probably an adequate dose in most affluent societies. In developed countries, individual iron prophylaxis guided by iron status (serum ferritin has physiological advantages compared to general iron prophylaxis. In contrast, in most developing countries, general iron prophylaxis is indicated, and higher doses of oral iron, for example, 60 mg ferrous iron or even more should be recommended, according to the present iron status situation in the specific populations of women of fertile age and pregnant women.

  13. Evaluation of Discrimination Indices Validity for Screening of β-Thalassemia Trait

    Directory of Open Access Journals (Sweden)

    Ahmadi A.

    2009-11-01

    Full Text Available AbstractBackground and Objectives: β-thalassemia trait (β-TT and iron deficiency anemia (IDA are the most common forms of microcytic anemia. Screening of β-thalassemia trait is important for medical counseling before marriage and preventing β-thalassemia major birth results. The most common problem in screening -TT is differentiating it from IDA. The aim of this study was to define the sensitivity, specificity, and predictive values of some discrimination indices for screening of β-TT in a sample of such patients.Methods: A total of 82 patients with microcytic anemia (MCV< 80 fl were selected from Namazi Hospital, Shiraz, Iran, and 9 discrimination indices were calculated for them. The patients were divided intotwo groups: 42 patients with β-TT and 40 patients with IDA. The sensitivity, specificity, positive and negative predictive values and Youden,s index of each discrimination index were calculated for screening β-TT.Results: None of the discrimination indices showed 100% of sensitivity and specificity. But the Shin and Lal index, RDW index and RBC count showed the highest and valuable value for screening β-TT.Conclusion: Some discrimination indices like Shin and Lal index, RDW index and RBC index are valuable indices in screening β-TT.Keywords: Beta- Thalassemia; Anemia, Iron Deficiency.

  14. Residents' Self-Reported Health Effects and Annoyance in Relation to Air Pollution Exposure in an Industrial Area in Eastern-Estonia.

    Science.gov (United States)

    Orru, Hans; Idavain, Jane; Pindus, Mihkel; Orru, Kati; Kesanurm, Kaisa; Lang, Aavo; Tomasova, Jelena

    2018-02-02

    Eastern Estonia has large oil shale mines and industrial facilities mainly focused on electricity generation from oil shale and shale oil extraction, which produce high air pollution emissions. The "Study of the health impact of the oil shale sector-SOHOS" was aimed at identifying the impacts on residents' health and annoyance due to the industrial processing. First, a population-wide survey about health effects and annoyance was carried out. Second, the total and oil shale sectors' emitted concentrations of benzene, phenol, and PM 2.5 were modelled. Third, the differences between groups were tested and relationships between health effects and environmental pollution studied using multiple regression analysis. Compared to the control groups from non-industrial areas in Tartu or Lääne-Viru, residents of Ida-Viru more frequently ( p sector. Next to direct health effects, up to a quarter of the residents of Ida-Viru County were highly annoyed about air pollution. Perceived health risk from air pollution increased the odds of being annoyed. Annoyed people in Ida-Viru had significantly higher odds of experiencing respiratory symptoms during the last 12 months, e.g., wheezing (2.30, 1.31-4.04), chest tightness (2.88, 1.91-4.33 or attack of coughing (1.99, 1.34-2.95).

  15. Iron deficiency anaemia: with the conclusion of a need for iron reader

    Science.gov (United States)

    Lim, Wai Feng; Yap, Boon Kar; Lai, Mei I.; Talik, Noorazrina; Nasser, Ammar Ahmed; Al-Haiqi, Ahmed Mubarak Ahmed; Sankar Krishnan, Prajindra

    2017-10-01

    In our bloodstream, there are plenty of red blood cells (RBC), which function as an important oxygen carrier in our bodies. Each RBC consists of millions of haemoglobin (Hb), which is made up from globin and iron. If any deficiency/malfunction of any globin, it will lead to anaemia as indicated in low Hb level while iron deficiency anaemia (IDA) is anaemic due to the lacking of iron as indicated in low Hb and ferritin levels. IDA affects almost two billion people globally while anaemia without iron deficiency, such as thalassaemia, affects almost 4.5% in Malaysian population. These anaemic conditions have similar clinical symptoms like fatigue, dizziness, in which disturb their cognitive development and productivity in workplace. In areas without proper medical access, many anaemic individuals were misdiagnosed and treated with iron tablets because they were thought to have iron deficiency anaemia due to low Hb content. But, excess iron is toxic to the body. Misdiagnosis can be avoided by iron status assessment. We hereby review the currently available iron status parameters in laboratory and field study with the conclusion of demonstrating the importance of a need for iron reader, in the effort to reduce the prevalence of IDA globally.

  16. Dietary Intake of Iron Rich Food and Awareness on Iron Deficiency Anaemia among Female Students in Rawalpindi

    International Nuclear Information System (INIS)

    Siddiqui, F. R.; Usmani, A. Q.; Shahid, A.; Sadiq, T.

    2013-01-01

    Objective: To assess the awareness and intake of iron rich diet amongst college girls with a particular focus on the knowledge about the iron deficiency anaemia. Materials and Methods: A cross sectional survey was conducted in Government College for Women Rawalpindi, during September - December 2010. One hundred and thirty five students of intermediate level aged 17-19 years were selected through convenient sampling technique. The sample size was calculated by WHO-sample size calculator, keeping 95 percent Cl, p<0.05 statistically significant, anticipated population proportion of iron deficiency anaemia 35 percent and absolute precision at 0.08. Results: The awareness about iron rich diet and iron deficiency anaemia was satisfactory (86 percent), while poor intake of iron rich diet amongst adolescent college girls (52 percent) was found. About 65 percent of the participants had knowledge about the causes of iron deficiency anaemia (IDA); while 72 percent and 80 percent knew about the prevention and treatment of IDA respectively. Conclusions: Results indicate the gap between knowledge and practices about IDA; it highlights the need of an effective health promotional programme to raise awareness about the significance of iron in young female diet and to highlight the consequences when it is absent. (author)

  17. Anaemia in pregnancy.

    Science.gov (United States)

    Goonewardene, Malik; Shehata, Mishkat; Hamad, Asma

    2012-02-01

    Anaemia in pregnancy, defined as a haemoglobin concentration (Hb) anaemia in pregnancy, nutritional iron deficiency anaemia (IDA) being the commonest. Underlying inflammatory conditions, physiological haemodilution and several factors affecting Hb and iron status in pregnancy lead to difficulties in establishing a definitive diagnosis. IDA is associated with increased maternal and perinatal morbidity and mortality, and long-term adverse effects in the new born. Strategies to prevent anaemia in pregnancy and its adverse effects include treatment of underlying conditions, iron and folate supplementation given weekly for all menstruating women including adolescents and daily for women during pregnancy and the post partum period, and delayed clamping of the umbilical cord at delivery. Oral iron is preferable to intravenous therapy for treatment of IDA. B12 and folate deficiencies in pregnancy are rare and may be due to inadequate dietary intake with the latter being more common. These vitamins play an important role in embryo genesis and hence any relative deficiencies may result in congenital abnormalities. Finding the underlying cause are crucial to the management of these deficiencies. Haemolytic anaemias rare also rare in pregnancy, but may have life-threatening complications if the diagnosis is not made in good time and acted upon appropriately. Copyright © 2011 Elsevier Ltd. All rights reserved.

  18. Anna-Maria Galojan: jah-liikumisega võivad liituda kõik soovijad / Anna-Maria Galojan ; interv. Ishtvan Ban

    Index Scriptorium Estoniae

    Galojan, Anna-Maria, 1982-

    2003-01-01

    Ilmunud ka: Severnoje Poberezhje : Subbota 2. aug. lk. 1. Eesti Euroopa liikumise Ida-Virumaa tugikeskuse piirkondlik koordinaator Anna-Maria Galojan oma organisatsioonist, noorte vabatahtlike tööst

  19. Kurt Volker: USA peab uue entusiasmiga lahendama vanu probleeme / Kurt Volker ; intervjueerinud Evelyn Kaldoja

    Index Scriptorium Estoniae

    Volker, Kurt

    2009-01-01

    USA NATO suursaadik president Barack Obamat ootavatest välispoliitilistset probleemidest, NATO poliitikast Gruusia jt. Ida-Euroopa riikide suhtes, Venemaa ja Ukraina gaasitülist ja suhetest Venemaaga

  20. Fostering deep and comprehensive free trade agreements for the eastern partners / Per Magnus Wijkman

    Index Scriptorium Estoniae

    Wijkman, Per Magnus

    2011-01-01

    Laiaulatusliku ja kõikehõlmava vabakaubanduslepinguga (DCFTA) liitumise läbirääkimistest ELi idapartnerluse riikidega. Ida-Euroopa riikide ühinemisest kaupade ja teenuste vaba liikumisega. Joonised

  1. Euroopa Liidu lävel / Tiiu Sizova

    Index Scriptorium Estoniae

    Sizova, Tiiu

    2003-01-01

    Ilmunud ka: Severnoje Poberezhje : Okruzhajushtshaja Sreda 6. dets. lk. 1. Eesti keskkonnahoiu seisukohalt on Ida-Virumaa üks problemaatilisemaid piirkondi, ülesanded seoses rahvusvaheliste direktiivide täitmisega

  2. Kesk-Euroopa on Euroopa Liidu tähtis kaubanduspartner / Lembo Tanning

    Index Scriptorium Estoniae

    Tanning, Lembo

    1999-01-01

    Kaubandusest Euroopa riikide ja Euroopa Liidu liikmesriikide vahel. Joonised: Kesk-Euroopa maade ekspordi ja -impordipartnerid, ELi eksport-import, ELi riikide väliskaubandus Kesk- ja Ida-Euroopa riikidega

  3. Accounting for heterogeneity in cross-country bank efficiency comparisons. The case of new EU member states / Marko Košak, Jelena Zorić

    Index Scriptorium Estoniae

    Košak, Marko

    2011-01-01

    Artiklis käsitletakse heterogeensuse probleemi panga efektiivsuse uuringutes, kasutades stohhastilist tehnikat ning uurimisobjektideks Euroopa Liidu uued liikmesriigid Kesk- ja Ida-Euroopast (sh Eesti) aastatel 1998-2007. Tabelid

  4. Assessment of Industry Investment in U.S. Domestic Production of Strategic Materials

    National Research Council Canada - National Science Library

    Arnold, Scot A; Tyson, Karen W; Aronin, Benjamin S

    2008-01-01

    IDA assisted the Strategic Materials Protection Board in assessing the extent to which domestic producers of strategic materials are investing to ensure continued domestic production of these materials...

  5. Demokraatia mitu elu / Karin Dean, Märt Läänemets

    Index Scriptorium Estoniae

    Dean, Karin

    2014-01-01

    Demokraatiast ühiskonnas Aasia ja Ida-Euroopa riikide näitel. Tallinna Ülikooli Eesti Humanitaarinstituudi korraldatud rahvusvahelisest konverentsist "Demokraatia mitu elu: Euroopast Aasia ja Vaikse ookeani regioonini"

  6. The democratic experience in divided societies : the Baltic states in comparative perspective / Geoffrey Evans, Christine S Lipsmeyer

    Index Scriptorium Estoniae

    Evans, Geoffrey

    2001-01-01

    Artiklis võrreldakse vähemusrahvuste rahulolu demokratiseerimisprotsessiga ning osalemist demokraatlikes protsessides kolmes Balti riigis ning kümnes Ida-Euroopa riigis 1990. aastail. Tabelid. Lisa: The surveys

  7. Impact of foreign banks on banking sector stability in Central and Eastern European countries / Janek Uiboupin

    Index Scriptorium Estoniae

    Uiboupin, Janek, 1976-

    2005-01-01

    Välispankade mõjust Kesk- ja Ida-Euroopa pangandussektori stabiilsuse kujunemisele, kohaliku pangandusturu laenupakkumisele ning krediidiriskile, rollist panganduskriisi järgsel turu rehabiliteerimisel. Tabelid. Diagrammid. Lisad lk. 108

  8. Estonia's Alta buys Lauma lingerie

    Index Scriptorium Estoniae

    2004-01-01

    Eesti investeeringute firma Alta Capital ostis 76,4 protsenti pesutootja Lauma aktsiatest. Tulevikus plaanitakse suunduda Ida- ja Lääne-Euroopa turgudele. Alta Capital omab 79 protsenti Klementi aktsiatest

  9. Hillitsetud feministid / Teet Veispak

    Index Scriptorium Estoniae

    Veispak, Teet, 1955-

    2000-01-01

    Ajakirja "Ariadne Lõng" esinumbrist, mis esindab liberaalse feminismi vaateid. Katrin Kivimaa artiklist "Teise tootmine - Ida-Euroopa ja feminism". Esile on tõstetud kunstiteadlaste Reet Varblase ja Eda Sepa artiklid.

  10. Ken-Marti Vaher : Paremjõudude ühinemine on Res Publica esmane ülesanne / Ken-Marti Vaher ; interv. Tanel Mazur

    Index Scriptorium Estoniae

    Vaher, Ken-Marti, 1974-

    2004-01-01

    Ilmunud ka: Narvskaja Gazeta, 6. nov. 2004, lk. 2. Ida-Virumaad külastanud justiitsminister Ken-Marti Vaher Rakveres ja Narvas arutatust, praeguse võimupartei Res Publica seisukohtadest, tulevikuplaanidest

  11. Lokomotivõ regiona - biznes, tranzit i turizm / Jevgeni Ashihmin

    Index Scriptorium Estoniae

    Ashihmin, Jevgeni

    2007-01-01

    8.-9. veebruaril korraldatakse Ida-Virumaal rahvusvaheline konverents, mille diskussiooniteemadeks on regionaalne areng, transiit, infrastruktuurid, majanduskoostöö Venemaaga, raudteetransport Tallinna ja Peterburi vahel, koostöö linnade vahel

  12. Ärkamisaeg / Urve Erikson

    Index Scriptorium Estoniae

    Erikson, Urve, 1956-

    2004-01-01

    Ilmunud ka: Severnoje Poberezhje, 1. dets. 2004, lk. 2. Ida-Virumaa Omavalitsuste Liidu tegevdirektor viitab narkomaaniavastase võitluse ja narkoennetustöö nõrkusele maakonnas ja selle põhjustele

  13. Uued noortemajad Sinimägede kanti / Tiit Elner

    Index Scriptorium Estoniae

    Elner, Tiit

    2000-01-01

    Presidendi väljapakutud idee rajada riigi toetusel Ida-Virumaale noorte uus asum on muundumas korraliku eluaseme pakkumiseks kohalike tööstusettevõtete juhtidele ja kõrgepalgalistele spetsialistidele

  14. IDA's Outreach to Asia-Pacific Research Institutions

    National Research Council Canada - National Science Library

    Hassig, Kongdan

    1998-01-01

    .... Asian think tanks have traditionally produced less independent and creative research than their American counterparts, reflecting the fact that most Asian think tanks are government-run and a strong...

  15. Lähis-Ida võitlus ägeneb

    Index Scriptorium Estoniae

    2006-01-01

    Iisraeli valitsus otsustas 19. juulil toimunud istungil, et jätkab operatsioone Gaza sektoris ja Liibanonis. Lähis-Itta konflikti lahendama saabunud Euroopa Liidu välisasjade koordinaator Javier Solana kutsus Iisraeli ja Liibanoni äärmusrühmitust Hezbollah vaenutegevust lõpetama

  16. 2469-IJBCS-Article-Ida Attabé Manney

    African Journals Online (AJOL)

    hp

    subequatorial climate characterized by two rainy seasons, a short ..... Figure 3: Redundancy analysis ordination diagram applied to environmental variables and zooplankton ..... Vertical migrations and feeding rhythms of Acartia clausi and.

  17. US politics and World Bank IDA-lending

    DEFF Research Database (Denmark)

    Andersen, Thomas Barnebeck; Hansen, Henrik; Markussen, Thomas

    2006-01-01

    This paper studies the role of US political factors in the allocation of World Bank concessional lending, where US political interests are proxied by voting similarity in the United Nations General Assembly on issues identified as important by the US Department of State. In contrast to previous...

  18. Pro Kapital sihib ida suunas / Raigo Neudorf

    Index Scriptorium Estoniae

    Neudorf, Raigo

    2007-01-01

    Peamiselt itaallastele kuuluv kinnisvaraarendaja Pro Kapital Group suunab edaspidi oma põhitegevuse Venemaale ja Ukrainasse, kuid jätkab kinnisvaraprojektide arendamisega Eestis ja Lätis. Vt. samas: Preatoni juhib Domina tegevust; Pro Kapital laiendab Kristiine keskust; Arco Vara juht kiidab Pro Kapitali ning nende projekte; Kümme aastat Pro Kapitali juhina

  19. Ida-Euroopa kunstnikud koostöövalmis

    Index Scriptorium Estoniae

    2002-01-01

    21. II-31. III Tallinna Kunstihoones Viinis ja Budapestis tegutseva galeristi ja kuraatori Hans Knolli koostatud näitus "An artist who does not speak English is not an artist". Osalevad Lucehezar Boyadijev (Sofia), Aleksandr Brener, Barbara Schurz (Moskva, Viin), Rza El-Hassan (Budapest), Kai Kaljo, Roman Ondák (Bratislava), Mladen Stilinovic (Zagreb), Milica Tomic (Belgrad). Avamisel K. Kaljo performance

  20. Peaminister lendas Ida-Virus ringi / Argo Soolep

    Index Scriptorium Estoniae

    Soolep, Argo, 1972-

    2004-01-01

    Ilmunud ka: Severnoje Poberezhje, 17. apr. 2004, lk. 1. Peaminister Juhan Parts ja siseminister Margus Leivo kohtusid Kohtla-Järve linnapea Jevgeni Solovjoviga ning kontrollisid koos piirivalvetöötajatega Euroopa Liidu idapiiri kordoneid

  1. NIMS EXPERIMENT DATA RECORDS: GASPRA/IDA ENCOUNTERS

    Data.gov (United States)

    National Aeronautics and Space Administration — NIMS Experiment Data Record (EDR) files contain raw data from the Galileo Orbiter Near-Infrared Mapping Spectrometer (CARLSONETAL1992). This raw data requires...

  2. Eesti maksusüsteem liitumisel Euroopa Liiduga / Olev Raju

    Index Scriptorium Estoniae

    Raju, Olev, 1948-

    2004-01-01

    Ülevaade Eesti maksusüsteemi kujunemisest ja makromajanduslikust toimest alates 1993. aastast. Tabelid: Eesti majanduse arengut iseloomustavaid arve 1998-2003; Ettevõtte tulumaksu iseloomustavaid arve Ida-Euroopa maades (2002)

  3. Review of Department of Defense Education Activity (DODEA) Schools. Volume II: Quantitative Analysis of Educational Quality

    National Research Council Canada - National Science Library

    Anderson, Lowell

    2000-01-01

    This volume compiles, and presents in integrated form, IDA's quantitative analysis of educational quality provided by DoD's dependent schools, It covers the quantitative aspects of volume I in greater...

  4. Visit to China's ARJ21 Aircraft Manufacturing Facility

    National Research Council Canada - National Science Library

    Balut, Stephen J; McNicol, David L; Nelson, J. R; Harmon, Bruce R; Holder, Stephen G

    2008-01-01

    During a December 2007 visit to China to share information about civilian aircraft costs, a delegation from IDA visited the Shanghai Aircraft Manufacturing Facility where the commercial chinese ARJ21...

  5. Expansion of the North Atlantic Treaty Organization and Russian national security strategy : compatible consepts? / Lisa Vining

    Index Scriptorium Estoniae

    Vining, Lisa

    2002-01-01

    Venemaa julgeolekustrateegiad ja sõjaline doktriin, Venemaa riikliku julgeoleku suurimad ohustajad - Tšetšeenia, Dagestan, Kesk-Aasia ja Kaug-Ida. Võimalused, et Venemaa muudab oma seisukohti NATO laienemise suhtes

  6. Ago Silde : "Olin täiesti ebatüüpiline maavanem" / Ago Silde ; interv. Erik Gamzejev

    Index Scriptorium Estoniae

    Silde, Ago

    2007-01-01

    Ilmunud ka: Severnoje Poberezhje : Subbota, 12. mai 2007, lk. 3. Intervjueeritav teeb tagasivaate oma tööle Ida-Viru maavanemana, ka parlamendivalimistest. Arvamust avaldavad Tõnis Seesmaa ja Urve Erikson

  7. Vidyasagar, Dr Mathukumalli

    Indian Academy of Sciences (India)

    Elected: 1992 Section: Engineering & Technology ... Address: Cecil & Ida Green Chair of Systems Biology Science, Erik Jonsson School of Engineering & Computer Science, The University of Texas at Dallas, ... Upcoming Refresher Courses.

  8. Democracy questioned

    Index Scriptorium Estoniae

    2011-01-01

    Ülevaade Kagu- ja Ida-Euroopa riikides läbiviidud küsitluste tulemustest majanduskriisi mõjude kohta demokraatiale ja vabaturu mehhanismidele, mis on avaldatud EBRD aruandes "Transition Report 2011"

  9. Saksamaa frankofiilne välispoliitika - tupikus tee / Jeroen Bult

    Index Scriptorium Estoniae

    Bult, Jeroen

    2003-01-01

    Hollandi ajaloolane ja publitsist Jeroen Bult Saksamaa ja Prantsusmaa, Saksamaa ja USA suhetest. Autori sõnul on Saksamaa ühepoolne orientatsioon Prantsusmaale viinud Saksamaa kaugemale oma traditsioonilistest huvidest Ida-Euroopas

  10. Jung und Alt im Dialog

    Directory of Open Access Journals (Sweden)

    Caroline Baetge

    2012-04-01

    Full Text Available Rezension zu: Kupser, Thomas, und Ida Pöttinger, Hrsg. 2011. Mediale Brücken: Generationen im Dialog durch aktive Medienarbeit. Gesellschaft - Altern - Medien 3. München: kopaed.

  11. Investigating the early signals of banking vulnerability in Central and East European emerging markets / Kadri Männasoo

    Index Scriptorium Estoniae

    Männasoo, Kadri

    2005-01-01

    Uuringust selgus, et kõrgem laenu osakaal panga varades viitas EL-i uute liikmesriikide puhul riskantsematele pankadele, Kesk- ja Ida-Euroopa riikide puhul oli sama fenomen stabiilsemate pankade tunnuseks. Tabelid

  12. Advent Euroopa viienda õiega

    Index Scriptorium Estoniae

    1999-01-01

    Esimesel advendil Tallinnas toimunud Taivo Pilleri jõuludemonstratsioonil osalesid edukalt ka kaks Ida-Viru lilleseadjat: Karin Lainjärv ja Marietta Rossmann; paremateks tunnistati Irmen Laving, Saale Halla, Heidi Haggi

  13. 10 kohta veel all / Kaido Haagen

    Index Scriptorium Estoniae

    Haagen, Kaido

    2014-01-01

    Sukeldumiskohti maailmas: Similani saared Tais, Averoy Norras, Tofo Mosambiigis, Punane meri Egiptuses, Sipadani saar Malaisias, Dili Ida-Timoris, Tulamben Balil, Lembeh Indoneesias, Malapascua Filipiinidel, Äntu järved Eestis

  14. Uikala prügila sai puhastusseadmed / Külli Kriis

    Index Scriptorium Estoniae

    Kriis, Külli, 1961-

    2004-01-01

    Ilmunud ka: Severnoje Poberezhje, 22. mai 2004, lk. 3. 21. mail 2004 Ida-Virumaal Uikala prügilas avatud puhastusseadmete kompleksist, mille valmistas ja paigaldas rahvusvaheline ettevõte Pall Corporation

  15. Kuidas kirjutada kunstiajalugu? / Anu Allas

    Index Scriptorium Estoniae

    Allas, Anu, 1977-

    2010-01-01

    14. ja 15. mail 2010 Tallinnas toimunud USA Clarki instituudi ja Eesti Kunstiakadeemia Kunstiteaduse Instituudi seminarist "Thinking Art History in East-Central Europe" (Arutlusi Kesk- ja Ida-Euroopa kunstiajaloo teemal)

  16. Res Publica objedinjajetsja s Sojuzom Otetshestva

    Index Scriptorium Estoniae

    2006-01-01

    Res Publica ja Isamaaliidu liitumisel tekib uus erakond - Eesti Eest!. Ida-Viru Isamaaliidu ja Res Publica esimeeste Hans Pindre, Vladislav Ponjatovski ning Narva Res Publica endise liidri Nikolai Golubevi arvamused

  17. Les aides europeennes aux PECO : Vers une meilleure affectation des fonds? / Aude Hapiot, Assen Slim

    Index Scriptorium Estoniae

    Hapiot, Aude

    2003-01-01

    Euroopa Liiduga liituvatele Kesk- ja Ida-Euroopa riikidele antud välisabist, erinevatest abiprogrammidest (Phare, ISPA, SAPARD) ja fondidest, abiandmise põhimõtetest ning projektide jaoks raha taotlemise korrast. Tabelid

  18. Microsoft võttis Eesti koostööpakkumise vastu / Kristjan Otsmann

    Index Scriptorium Estoniae

    Otsmann, Kristjan, 1971-

    2004-01-01

    Ida-Euroopa riikide ja Microsofti ümarlaud Slovakkias Bratislavas. Microsofti asutaja Bill Gates oli huvitatud Meelis Atoneni ettepanekust, et riik korraldab oma kodanikele Microsofti tarkvara rentimise neile vastuvõetava hinnaga

  19. Review of empirical studies on disclosure and MBAR in European countries / Laivi Laidroo

    Index Scriptorium Estoniae

    Laidroo, Laivi

    2006-01-01

    Artikkel koondab teavet erinevate teostatud empiiriliste uuringute kohta, kirjeldab nende peamisi iseloomulikke jooni ning toob välja potentsiaalsed uurimissuunad, mis oleksid aktuaalsed Kesk- ja Ida-Euroopa riikide kontekstis. Tabelid

  20. Raznõje, no ravnõje / Jevgenija Zelenskaja

    Index Scriptorium Estoniae

    Zelenskaja, Jevgenija

    2007-01-01

    Jõhvis toimus seminar "Tolerantsus rahvusvahelistes suhetes", kus esinesid USA teadlane Jeremy Gunn, rahvastikuministri nõunik Eva-Maria Asari, Viru kolledzhi esindaja Sergei Tshekrõzhov, Ida-Viru integratsioonikeskuse esindaja Heli Fershel

  1. Pop / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2008-01-01

    Heliplaatidest: Paavoharju "Laulu laakson kukista", Lau Nau "Nukkuu", Mari-Leen "1987", Urt "Ussikuningas", Emmylou Harris "All Intended To Be", rasKatarsis "rasKatarsis", Nemos "Ida Sinine", OTK1 "Instrumentaal Eksperimentaal"

  2. Let Obama be Obama! / Toomas Alatalu

    Index Scriptorium Estoniae

    Alatalu, Toomas, 1942-

    2010-01-01

    USA politoloogi ja julgeolekueksperdi Zbigniew Brzezinski artiklist "Lootusest julguseni" ajakirjas Foreign Affairs, milles autor lahkab president Barack Obama välispoliitikat. USA Lähis-Ida poliitikast ja USA- Iisraeli suhetest

  3. Update on radionuclide imaging in hepatobiliary disease

    International Nuclear Information System (INIS)

    Rosenthall, L.

    1981-01-01

    The recent introduction of technetium Tc 99m-labeled acetanilide iminodiacetic acid (/sup 99m/Tc-IDA) analogues has facilitated the clincal study of the bile flow pathways. A variety of /sup 99m/Tc-IDA derivaties are under investigation. Basically all are metabolized by the hepatocyte and immediately thereafter excreted unconjugated into the biliary tract. Of the various derivatives tested, e.g., dimethyl (lidofenin), diethyl, paraisopropyl (iprofenin), parabutyl (butilfenin), and diisopropyl (disofenin), the last named is the best universal agent at this time. By serial liver imaging the patency of the cystic duct and the integrity of altered cholangiointestinal anatomy can be assessed, leakage of bile and gastric reflux can be disclosed, and medical and surgical jaundice can be distinguished

  4. Prantsusmaa esimene mees alustas lahingutega / Erkki Bahovski

    Index Scriptorium Estoniae

    Bahovski, Erkki, 1970-

    2007-01-01

    Prantsusmaa presidendi Nicolas Sarkozy soovist rakendada Euroopa Keskpanka Prantsuse majanduse edendamisse ja tuua riik välja välispoliitilisest isolatsioonist. Suhete arendamisest Liibüa, USA, Venemaa ja Ida-Euroopaga

  5. Explaining cross-national variations in the informalisation of employment. Some lessons from Central and Eastern Europe / Colin C. Williams

    Index Scriptorium Estoniae

    Williams, Colin C.

    2015-01-01

    Kesk- ja Ida-Euroopa (sh Eesti) riikide vahelistest erinevustest mitteametlikus tööhõive kolmest teoreetilisest seisukohast (moderniseerimine, neoliberaalne, poliitiline ökonoomia) lähtuvalt, aluseks 2007. aasta Eurobaromeetri uuring.

  6. Who Gets into Government? Coalition Formation in European Democracies / Holger Döring, Johan Hellström

    Index Scriptorium Estoniae

    Döring, Holger

    2013-01-01

    Valitsuste formeerumise erinev dünaamika 26 euroopa demokraatias (sealhulgas Eesti). Esimene valitsuses osalemise otsustavate tegurite süstemaatiline võrdlus ja erinevused Ida- ja Lääne-Euroopa riikide vahel

  7. Heitlik ilm süvendab luu- ja liigesevalu / Anneli Aasmäe

    Index Scriptorium Estoniae

    Aasmäe, Anneli, 1973-

    2008-01-01

    Tartu Ülikooli Kliinikumi sisekliiniku reumatoloogia dotsendi Riina Kallikormi, Kuressaare erakliiniku Luukas reumatoloogi Reinhold Birkenfeldti ja Ida-Tallinna Keskhaigla reumatoloogi Tõnu Peetsi kinnitusel on kõik krooniliste reumaatiliste haigustega inimesed ilmatundlikud

  8. Forum na granitse / Jevgeni Ashihmin

    Index Scriptorium Estoniae

    Ashihmin, Jevgeni

    2008-01-01

    Narvas 15. mail toimuvast riikide töögruppide kohtumisest, mille arutlusteemaks on kaasaegse tehnoloogia kasutamine ummikute vältimiseks riigipiiride ületamisel ja Ida-Virumaa majandusprobleeme käsitlevast konverentsist

  9. Excuse me, are you the last here? / Hanno Soans

    Index Scriptorium Estoniae

    Soans, Hanno, 1974-

    2003-01-01

    Rotermanni soolalaos 2003 a. sügisel toimunud rahvusvahelisest näitusest "Viimane kangelane", kus oma nägemust kangelasest tutvustab 23 kunstnikku Ida-Euroopast. Kuraatorid Hanno Soans ja Eha Komissarov

  10. Saksa ettevõtete optimism jätkub

    Index Scriptorium Estoniae

    2014-01-01

    Vaadeldes asukohamaaga seotud kriteeriume nii üksikult kui tervikuna, on Eesti, Läti ja Leedu - võrreldes teiste Ida- ja Kesk-Euroopa riikidega - siin tegutsevate saksa ettevõtete arvates hinnatud asukohamaad

  11. Konverents "Piiri kood" / Tuulikki Kurki

    Index Scriptorium Estoniae

    Kurki, Tuulikki

    2014-01-01

    6.-8. nov. 2013. a. toimus Ida-Soome ülikooli Joensuu kampuses konverents "Piiri kood" ("Border Code"), kus arutleti piiride üle interdistsiplinaarses uurimises kasutatavate mõistete, teooriate ja meetodite puhul

  12. Politiki speshno dvinuliss na vostok / Jekaterina Petra

    Index Scriptorium Estoniae

    Petra, Jekaterina

    2006-01-01

    Riigikogu SDE fraktsiooni juhi Ivari Padari ja parlamendiliikme Peeter Kreitzbergi juhtimisel külastasid sotsiaaldemokraadid Ida-Virumaad, kohtuti õpetajate, meditsiinitöötajate, kohalike ametiühingute liidritega ning ühiskonnategelastega

  13. No miracles for EU candidates / Jean-Luc Testault

    Index Scriptorium Estoniae

    Testault, Jean-Luc

    2003-01-01

    Kuigi Iirimaa majanduskasv on Euroopa Liidus olnud märkimisväärne, prognoositakse, et Ida-Euroopa liituvate riikide majandus hakkab Euroopa Liidus arenema Portugali ja Hispaania majandusmudeli järgi

  14. Reactive Identity versus EU Integration / Raivo Vetik, Gerli Nimmerfelft, Marti Taru

    Index Scriptorium Estoniae

    Vetik, Raivo

    2006-01-01

    Avaliku arvamuse hinnang eurointegratsioonile, euroskeptitsismi põhjustest Eestis ning teistes Kesk- ja Ida-Euroopa riikides. Eesti, Slovakkia, Sloveenia, Poola, Ungari ja Tšehhi võrdlev analüüs. Diagramm, tabelid

  15. Eesti Halmas ja Halma Eestis / Mart Siilmann

    Index Scriptorium Estoniae

    Siilmann, Mart

    2008-01-01

    Kesk- ja Ida-Euroopa kirjanduskeskuste poolt loodud loomemajade võrgustikust Halma, kuhu kuulub ka Eesti Kirjanike Liidu Käsmu maja. Esimeseks külaliseks Käsmus oli austria kirjanik Richard Obermayr

  16. Kaasomand : korterelamu korrashoiu probleemid / Roode Liias

    Index Scriptorium Estoniae

    Liias, Roode, 1953-

    2003-01-01

    ÜRO Euroopa Majanduskomisjoni ekspertide poolt koostatud juhendmaterjalist ühistute töö korraldamiseks Kesk- ja Ida-Euroopa riikides ("Guidelines on condominium ownership of housing for countries in transition." UN; 2003)

  17. Bez kota mõsham razdolje / Jevgeni Kapov

    Index Scriptorium Estoniae

    Kapov, Jevgeni

    2004-01-01

    Sillamäe linnapea Ain Kiviorgi ja Vaivara vallavanema Veiko Luhalaidi kohtumisest Politseiameti peadirektori Robert Antropovi ja Ida politseiprefekti Kalev Prillopiga, kus arutati seoses politseireformiga Sillamäe regioonis tekkinud korrakaitse probleeme

  18. Loodushariduskava viib lapsed ja looduse kokku / Külli Kriis

    Index Scriptorium Estoniae

    Kriis, Külli, 1961-

    2007-01-01

    Riikliku looduskaitsekeskuse Ida-Viru regiooni loodushariduskava järgi arendatakse maakonnas välja piisavalt loodusmaju ja -tube ning õpialasid ja matkaradu, mis võimaldavad loodusõpet kõigile lasteaia- ja koolilastele

  19. Profitability of foreign banks in Central and Eastern Europe. Does the entry mode matter? / Olena Havrylchyk, Emilia Jurzyk

    Index Scriptorium Estoniae

    Havrylchyk, Olena

    2011-01-01

    Artikli aluseks on Kesk- ja Ida-Euroopas (sh. Eesti) tegutseva 418 panga andmed aastatest 1993-2004, analüüsitakse, kuidas mõjutavad panga turule sisenemise viis ja emapank panga kasumlikkust. Tabelid

  20. CIA võis lennutada ja hoida vange ka Euroopa idaosas / Kaivo Kopli

    Index Scriptorium Estoniae

    Kopli, Kaivo

    2006-01-01

    Amnesty Internationali raportis antakse ülevaade kolme vahistatud Jeemeni mehe kogetust aastatel 2003-2005. Meeste tunnistustest järeldab Amnesty, et neid hoiti kinni ka Ida-Euroopas. Lisa: Kolme Jeemeni mehe tunnistused

  1. Godovshtshina bez eiforii / Aleksei Klepikov

    Index Scriptorium Estoniae

    Klepikov, Aleksei

    2005-01-01

    EL-i ja NATO-ga liitumise mõjudest Baltimaade elanike turvatundele ning majandusele. Arvamust avaldavad Tiit Matsulevitsh, Ivar Sikk, Toivo Kuldkepp jt. Toimetuse kommentaar. Diagramm: Inflatsioonimäärad Ida-Euroopa riikides

  2. Kristy Villems moves from Saku to Carlsberg / Kristy Villems

    Index Scriptorium Estoniae

    Villems, Kristy, 1975-

    2004-01-01

    Saku õlletehase turundusjuhi kohalt aastaks Carlsberg'i õlletehase turundusosakonna Kesk- ja Ida-Euroopa piirkonna projektijuhi kohale lahkunud Kristy Villems oma tulevastest tööülesannetest ning väljakutsetest uues ametis

  3. Mida jälgida aastal 2007? / Peeter Koppel

    Index Scriptorium Estoniae

    Koppel, Peeter

    2007-01-01

    Autori hinnangul peaks investor 2007. aastal jälgima Lähis-Idas toimuvaid konflikte, oodatud majanduskasvu, võimendatust globaalses finantssüsteemis, riske nii poliitilisel kui majanduslikul tasandil ning arvestama deflatsioonilise shokiga

  4. Korruptsioonihõng : politsei teeb Narvas suurpuhastust / Tanel Mazur, Kärt Anvelt

    Index Scriptorium Estoniae

    Mazur, Tanel, 1971-

    2008-01-01

    Seoses 2007. aasta augustis alustatud kriminaalasjaga otsis kaitsepolitsei Narvas läbi ka abilinnapea Sofia Homjakova kabineti, kriminaalasja raames pole kellelegi kahtlustusi esitatud. Vt. samas: Ärimehed: Ida-Virumaal maksab iga liigutus

  5. Toila ja Aseri vallas võivad tuulikud kerkima hakata / Külli Kriis

    Index Scriptorium Estoniae

    Kriis, Külli, 1961-

    2007-01-01

    Ida-Virumaale kerkib kolm uut tuuleparki: Toila valda kavandatava Päite-Vaivina tuulepargi arendajaks on OÜ Est Wind Power, Aseri valda rajatavate tuuleparkide arendajateks on OÜ Irben ja AS Windest Green Energy

  6. Skype'i kaasasutajad investeerivad MarkIT-isse

    Index Scriptorium Estoniae

    2007-01-01

    Nelja eestlasest Skype'i kaasasutaja loodud Ambient Sound Investments (ASI) investeerib 2 miljonit eurot, et aidata kaasa MarkIT e-hankekeskkonna arendamisele ning ettevõtte laienemisele viide Kesk- ja Ida-Euroopa riiki

  7. Ühendriikide endise presidendi juudikriitika vihastab ameeriklasi / Neeme Raud

    Index Scriptorium Estoniae

    Raud, Neeme, 1969-

    2007-01-01

    USA endise presidendi Jimmy Carteri raamatus "Palestiina: rahu, mitte apartheid" kirjutab autor Lähis-Ida rahosobitamisest ja peab rahukõneluste takerdumises süüdlaseks Iisraeli. Lisa: Katke Jimmy Carteri raamatust; Arvustus

  8. Srok za gumanizm / Julia Rodina

    Index Scriptorium Estoniae

    Rodina, Julia

    2008-01-01

    Soome ajalehes Aamulehti avaldati artikkel, et kauplused annavad humanitaarabiorganisatsioonidele realiseerimistähtaja ületanud toiduaineid ning neid tuuakse ka Eestisse, eriti vene elanikkonnaga piirkondadesse Ida-Virumaale. Veterinaar- ja toiduamet on alustanud uurimist

  9. Institutionalisierung durch Imitation? Die Europäisierung des Parlamentarismus in Mittel- und Osteuropa / Aron Buzogany

    Index Scriptorium Estoniae

    Buzogany, Aron

    2015-01-01

    Artikli teemaks on parlamentarismi euroopastumine Kesk- ja Ida-Euroopa riikides (sh Eesti), püüdes leida vastus küsimusele, kuidas on rahvusriikide parlamendid suutnud institutsionaalselt euroopastumise väljakutsele vastata?

  10. Golõshom i publitshno / Sofja Bauer, Tiia Linnard

    Index Scriptorium Estoniae

    Bauer, Sofia, 1947-2001

    1998-01-01

    Ida-Virumaa kunstnike kevadnäitusest Jõhvis, kujundas Aleksandr Igonin. Tutvustatakse osalevaid kunstnikke : Kalev Prits (Pump), Aleksandr Igonin, Aira ja Mati Rautso, Ljudmila Maisurjan, Andres Malõgin, Irja Annus, Juri Horev jt.

  11. Saudi rahuplaan ajas Iisraeli juhid tülli / Marek Laane

    Index Scriptorium Estoniae

    Laane, Marek, 1969-

    2002-01-01

    Saudi Araabia esitatud Lähis-Ida rahuplaan on ajanud Iisraeli juhtkonna tülli: peaminister Ariel Sharon on selle vastu, president Moshe Katsar on aga valmis saudidega kohtuma. Kaart: Iisraeli muutuvad piirid

  12. Piracy in Southeast Asia: A Growing Threat to the United States' Vital Strategic and Commercial Interests

    National Research Council Canada - National Science Library

    Davis, Gregory

    2002-01-01

    ... maritime targets of opportunity, a growing drug trade, China's attempts to exert sovereignty over the South China Sea, and new ominous link between the Osama Bin Ladin's Al-Qa'ida terrorist organization...

  13. Varjatud ajalugu ehk kuidas eksiilkunst kodu leidis = Hidden history, or how an exiled art found a home / Steven Mansbach

    Index Scriptorium Estoniae

    Mansbach, Steven, 1950-

    2009-01-01

    Euroopa 20. saj. kunsti ajaloo õpetamisest Ameerikas. Pärast Teist maailmasõda Ameerikasse emigreerunud kunstiteadlaste tegevusest. Ignoreerivast suhtumisest Ida-Euroopa maade kunsti. Geograafiliste, ajaliste ja kultuuriliste eripärade ületamise vajadusest

  14. Iga hea kunstnik on natuke dissident : dissidentlus / Enrico Crispolti ; interv. Maria-Kristiina Soomre

    Index Scriptorium Estoniae

    Crispolti, Enrico

    2007-01-01

    Itaalia kunstiteadlane ja kuraator Enrico Crispolti (sünd. 1933) Ida-Euroopa kunstist, dissidentlusest ja 1977. a. Veneetsia biennaalist, mille raames ta kureeris näitust "Uus kunst Nõukogude Liidust. Mitteametlik vaaternurk"

  15. IBMi presidenti hämmastas tasuta WiFi / Shaun T Jones

    Index Scriptorium Estoniae

    Jones, Shaun T

    2008-01-01

    2008. a. oktoobris Tallinnas IBMi Kesk- ja Ida-Euroopa äripartnerite kohtumisel viibinud IBMi tarkvaraosakonna asepresident räägib arengutest globaalses infotehnoloogia sektoris, küberkuritegevusest ja prognoosib IT-toodete tulevikku

  16. Prediction of seismic collapse risk of steel moment frame mid-rise structures by meta-heuristic algorithms

    Science.gov (United States)

    Jough, Fooad Karimi Ghaleh; Şensoy, Serhan

    2016-12-01

    Different performance levels may be obtained for sideway collapse evaluation of steel moment frames depending on the evaluation procedure used to handle uncertainties. In this article, the process of representing modelling uncertainties, record to record (RTR) variations and cognitive uncertainties for moment resisting steel frames of various heights is discussed in detail. RTR uncertainty is used by incremental dynamic analysis (IDA), modelling uncertainties are considered through backbone curves and hysteresis loops of component, and cognitive uncertainty is presented in three levels of material quality. IDA is used to evaluate RTR uncertainty based on strong ground motion records selected by the k-means algorithm, which is favoured over Monte Carlo selection due to its time saving appeal. Analytical equations of the Response Surface Method are obtained through IDA results by the Cuckoo algorithm, which predicts the mean and standard deviation of the collapse fragility curve. The Takagi-Sugeno-Kang model is used to represent material quality based on the response surface coefficients. Finally, collapse fragility curves with the various sources of uncertainties mentioned are derived through a large number of material quality values and meta variables inferred by the Takagi-Sugeno-Kang fuzzy model based on response surface method coefficients. It is concluded that a better risk management strategy in countries where material quality control is weak, is to account for cognitive uncertainties in fragility curves and the mean annual frequency.

  17. Incorporating Informatics for Integrating Biology and the Bedside (i2b2) into Predoctoral Trainee Curriculum to Evaluate Student-Generated Hypotheses.

    Science.gov (United States)

    Schieffer, Kathleen M; Peters, Douglas G; Richter, Chesney K; Loc, Welley S; Pawelczyk, James A

    2015-12-01

    As part of the Clinical and Translational Science Institute predoctoral TL1 training program at the Pennsylvania State University, a multidisciplinary team of predoctoral trainees representing the Chemistry, Neurosurgery, Nutritional Sciences, and Public Health Sciences departments were introduced to the NIH-sponsored Informatics for Integrating Biology and the Bedside (i2b2) database to test the following student-generated hypothesis: children with iron deficiency anemia (IDA) are at increased risk of attention deficit-hyperactivity disorder (ADHD). Children aged 4-12 and 4-17 years were categorized into IDA and control groups. De-identified medical records from the Penn State Milton S. Hershey Medical Center (HMC) and the Virginia Commonwealth University Medical Center (VCUMC) were used for the analysis. Overall, ADHD prevalence at each institution was lower than 2011 state estimates. There was a significant association between IDA and ADHD in the 4-17-year-old age group for all children (OR: 1.902 [95% CI: 1.363-2.656]), Caucasian children (OR: 1.802 [95% CI: 1.133-2.864]), and African American children (OR: 1.865 [95% CI: 1.152-3.021]). Clinical and Translational Science Award (CTSA) infrastructure is particularly useful for trainees to answer de novo scientific questions with minimal additional training and technical expertise. Moreover, projects can be expanded by collaborating within the CTSA network. © 2015 Wiley Periodicals, Inc.

  18. Relação entre as atividades conômicas e a qualidade ambiental nos municípios do Estado do Paraná

    Directory of Open Access Journals (Sweden)

    Carlos Alberto Gonçalves Junior

    2013-03-01

    Full Text Available El objetivo de este artículo es identificar las relaciones existentes entre la intensidad y concentración de la actividad económica y las condiciones ambientales en los municipios que conforman el estado de Paraná - Brasil. Primeramente se construye un Índice de Degradación Ambiental – (IDA utilizando los escores factoriales y el porcentaje explicado por cada factor del análisis factorial multivariado. Luego, se utilizó el coeficiente de correlación de Pearson para identificar la relación entre el PIB per capta de cada municipio y el índice estimado. Finalmente se usó la auto-correlación de datos espaciales – AEDE para identificar la existencia de un patrón espacial en el índice. Se constató que la correlación matemática entre el PIB per capta y el IDA estimado es positiva, o sea, municipios con mayor PIB per capta presentan mayor degeneración ambiental. La auto-correlación espacial del índice estimado también fue positiva, indicando un patrón espacial en el IDA estimado. Con los resultados obtenidos se puede constatar que la intensidad y la concentración de la actividad económica contribuyen para la degradación ambiental en los municipios paranaenses.

  19. Vancouver Olympic rings powered by fuel cell and IESO records winning goal

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2010-04-15

    The fuel cell system that provided power to the 30-foot tall floating Olympic Rings in Vancouver's harbour during the 2010 Winter Olympic Games was developed and manufactured by IdaTech in Bend, Oregon. The power source altered between a biodiesel generator and IdaTech's ElectraGen H2 zero emission hydrogen fuel cell system. The technology was chosen as a source of reliable, clean energy for applications in remote locations. The ElectraGen H2 is a hydrogen fueled proton exchange membrane (PEM) fuel cell system that emits only water vapour and heat, without any greenhouse gases. These solid state electric generators combine the best features of generators and batteries. IdaTech has sold over 400 of these fuel cell units to India and Asia to provide backup power to telecommunications networks. The 2010 Winter Olympic Games also provided an opportunity for Ontario's Independent Electricity System Operator (IESO) to track electricity consumption as people turned on their televisions to watch the Men's hockey final between Canada and the United States. An increase in electricity use of 300 MW occurred just before the game started and a similar increase occurred during the intermissions as viewers prepared snacks. Electricity consumption dropped considerably after overtime began and then climbed in the final stages of the game after the winning goal was scored. 2 figs.

  20. State of cognitive development in children 5-6 years of age with nutritional iron deficiency

    Directory of Open Access Journals (Sweden)

    Chechel V.V.

    2014-06-01

    Full Text Available Features of the development of cognitive functions in children 5-6 years of age with iron deficiency (ID were studied and the relationship of the revealed features of iron deficiency degree was established. After clinical and laboratory examination 205 children aged 5-6 years, pupils of pre-school institutions were included in the study. The core group consisted of 155 children, including 105 children with latent iron deficiency (LID and 50 children with iron deficiency anemia (IDA I degree. The control group consisted of 50 healthy children. To study cognitive function, "Approximate comprehensive program of study of children's readiness for school" was used. A significant decrease of average data of all mental functions (perception, memory, language, thinking, ima¬gination in children 5-6 years old with ID, most pronounced in children with IDA was revealed. Indicators of cognitive functions correspond predominantly to a mild and moderate level of development in children with IDA, the average - in children with LID, good and high - in healthy children. There was a significant direct correlation between the level of cognitive functioning and the level of hemoglobin, serum iron and ferritin. The effect of iron deficiency on the development of indicators of cognitive function toward their reduce in preschool children was established. The level of cognitive functioning depends on the degree of iron deficiency.

  1. Kohtla "majamasin" = Kohtla's Mining-Machine / Kaisa Kaer

    Index Scriptorium Estoniae

    Kaer, Kaisa

    2013-01-01

    Kohtla kaevanduspark Ida-Virumaal. Projekteerijad: Arden Arroval, Joonas Sarapuu / Innopolis Insenerid OÜ. Ekspositsiooni kujundus, sisekujundus ja asendiplaan: Margit Argus, Margit Aule / KAOS Arhitektid. 2014. a. valmib endise rikastusvabriku hoones maapealne külastuskeskus

  2. Speer teatrilaval

    Index Scriptorium Estoniae

    1999-01-01

    Londonis Almeida teatris mängitakse Esther Vilari näidendit "Speer". Saksa arhitekti ja ministrit kehastab austria näitleja Klaus Maria Brandauer. Näidendi tegevus toimub Ida-Saksamaal Berliinis aastal 1980

  3. Estonia pledges support for Palestine / Matt Withers

    Index Scriptorium Estoniae

    Withers, Matt

    2008-01-01

    Välisminister Urmas Paet teatas kohtumisel Palestiina välisministri Riyad al-Maliki'ga, et Eesti 12 miljoni krooni suurune annetus Palestiinale aitab kaasa riigi ülesehitamisele ja rahu tagamisele Lähis-Idas

  4. II samba eduks peaks liitujaid olema üle 50% / Kaja Koovit

    Index Scriptorium Estoniae

    Koovit, Kaja, 1968-

    2002-01-01

    Edukaks pensionireformi läbiviimiseks peaks teise samba kasuks otsustama enam kui pooled võimalikest liitujatest, väidab Ida-Euroopa pensionisüsteemi üks käivitajatest EBRD direktor Jonathan Wollett

  5. Rootsi näitab Eestit sarjates teadmatust / Gunilla Herlitz

    Index Scriptorium Estoniae

    Herlitz, Gunilla

    2004-01-01

    Autori arvates on majandusareng ja ühiskondlikud muutused EL-iga liituvates riikides viimase kuni viieteistkümne aasta jooksul olnud erakordsed, nüüd on Euroopa riikide kord õppida ida-poolsetelt riikidelt

  6. 19. ja 20. IV toimub Tartu kõrgemas kunstikoolis...

    Index Scriptorium Estoniae

    2002-01-01

    Konverentsi "Sharing the Future?", mis on pühendatud foto ja uue meedia hariduse küsimustele endises Ida-Euroopas, kava. Inglise fotograafi Robin Dance'i isiknäitus "Jaapani maastikud" Sebra galeriis

  7. Üleminek riigikeelsele gümnaasiumiõppele : vilistlaste seisukohtade Q-metodoloogiline diskursusanalüüs / Anu Masso, Katrin Kello, Valeria Jakobson

    Index Scriptorium Estoniae

    Masso, Anu, 1977-

    2013-01-01

    Keskendutakse diskursustele, mis on seotud riigikeelsele gümnaasiumiõppele üleminekuga senistes vene õppekeelega koolides. Uuring põhineb Tallinnas, Tartus, Ida-Virumaal ja Lätis läbi viidud Q-metodoloogilistel intervjuudel

  8. Rahvusvaheline lõimumist ergutav seminar ehk ребята, давайте жит дружно! / Ülly Enn

    Index Scriptorium Estoniae

    Enn, Ülly

    2008-01-01

    12.-16. oktoobril korraldas Sihtasutuse Archimedes Euroopa Noored Eesti büroo Ida-Virumaal rahvusvahelise seminari "Intercultural dialogue withhout subtitles", kus osalesid Eesti, Läti, Leedu, Saksamaa ja Soome noorsootöötajad

  9. Milk versus medicine for the treatment of iron deficiency anaemia in hospitalised infants

    OpenAIRE

    Wall, C; Grant, C; Taua, N; Wilson, C; Thompson, J

    2005-01-01

    Aims: To compare iron fortified follow-on milk (iron follow-on), iron fortified partially modified cows' milk (iron milk), and iron medicine for the treatment of iron deficiency anaemia (IDA) in hospitalised infants.

  10. Eredaid hetki "Pimedatest öödest" / Anne-Malle Hallik

    Index Scriptorium Estoniae

    Hallik, Anne-Malle

    2002-01-01

    Pimedate Ööde filmifestivali eredamaid muljeid : Mark Soosaare filmid Kinomajas, Danis Tanovici "Eikellegimaa", Ida-Saksamaa indiaanifilmide kangelane - serblasest filminäitleja Gojko Mitic ja David Riva dokumentaalfilm "Marlene Dietrich - tema oma laul"

  11. Moodne Magnum kasutab tipptaset / Tanel Raig

    Index Scriptorium Estoniae

    Raig, Tanel, 1975-

    2008-01-01

    Logistikateo konkursil esikoha saanud Magnum Logisticsi uus ladu on omataolistest Ida-Euroopas moodsaim. Vt. samas: Aasta logistikateo finaali jõudnud tööd olid suunatud efektiivsusele. Kommenteerivad Erki Lehiste ja Indrek Reismann

  12. Optimally funding Army Installation Repair and Maintenance Activities

    National Research Council Canada - National Science Library

    Bridges, Michael

    1997-01-01

    ...). The IDA contains a model called the Decision Support Tool (DST) that projects future infrastructure status given a proposed six year budget, the current infrastructure status, a funding hierarchy, and an infrastructure priority...

  13. Aasta algusest 24% plussi, veebruari lõpust 8% miinust

    Index Scriptorium Estoniae

    2005-01-01

    Ühispanga Varahalduse juhi Sven Kunsingu virtuaalportfelli seis aprilli alguses 2005. Tabel: Kunsingu virtuaalportfell 31.12.04-08.04.05. Vt. ka Profit nr. 2 lk. 42. Uued nopped Kesk- ja Ida-Euroopast

  14. [Influences of the mobile phase constitution, salt concentration and pH value on retention characters of proteins on the metal chelate column].

    Science.gov (United States)

    Li, R; Di, Z M; Chen, G L

    2001-09-01

    The effects of the nature and concentration of salts, pH value and competitive eluent in the mobile phase on the protein retention have been systematically investigated. A mathematical expression describing the protein retention in metal chelate chromatography has been derived. It is proposed that the eluting power of the salt solution can be expressed by the eluent strength exponent epsilon. According to the retention characters of protein under different chromatographic conditions, the interaction between the various metal chelate ligands and proteins is discussed. The protein retention on the metal chelate column is a cooperative interactions of coordination, electrostatic and hydrophobic interaction. For the strong combined metal column with proteins such as IDA-Cu, the coordination is the most important, and the electrostatic interaction is secondary in chromatographic process. However, for the weak combined metal columns with proteins such as IDA-Ni, IDA-Co and IDA-Zn, the electrostatic interaction between the metal chelate ligands and proteins is the chief one, while the coordination is the next in importance. When the mobile phase contains high concentration of salt which can't form complex with the immobilized metal, the hydrophobic interaction between the protein and stationary phase will be increased. As the interaction between the metal chelate ligand and proteins relates to chromatographic operating conditions closely, different elution processes may be selected for different metal chelate columns. The gradient elution is generally performed by the low concentration of salt or different pH for weakly combined columns with proteins, however the competitive elution procedure is commonly utilized for strongly combined column. The experiment showed that NH3 is an excellent competitive eluent. It isn't only give the efficient separation of proteins, but also has the advantages of cheapness, less bleeding of the immobilized metals and ease of controlling NH3

  15. Polypropylene fibers modified by plasma treatment for preparation of Ag nanoparticles.

    Science.gov (United States)

    Tseng, Chun-Hao; Wang, Cheng-Chien; Chen, Chuh-Yung

    2006-03-09

    A novel method for preparing poly(propylene-graft-2-methacrylic acid 3-(bis-carboxymethylamino)-2-hydroxy-propyl ester)-silver fibers (PPG-IAg fibers) by plasma-induced grafting polymerization is presented in this study. The chelating groups, -N(CH2COO-)2 (GMA-IDA), on the surface of the PPG-I fibers are the coordination sites for chelating silver ions. At these sites, Ag nanoparticles were grown first by reduction with UV light with a wavelength of 366 nm, and second, through immersion in a 24% formaldehyde solution with pH values set variously at 2, 5, 8, and 11. The characteristics of the PPG-I fibers with differing durations of plasma treatment were monitored by using a Fourier transform infrared (FT-IR) spectroscope. Scanning electronic microscopy (SEM) and elemental analysis show that the percentage of GMA-IDA grafted onto PP fiber reaches a maximum when the plasma treatment time is 3 min. Plasma treatment time beyond a certain length of time results in an abundance of free radicals and causes considerable cross-linking on the fiber surface which thus decreases the extent of grafting. Moreover, the crystalline phase of Ag nanoparticles is identified by using X-ray diffraction (XRD). When the PPG-I fibers are reduced by the UV light method, SEM and TEM microscopes reveal that the size of the Ag nanoparticles on the fiber surface decreases significantly with the increase of pH values in aqueous solutions. Notably, in the reduction of formaldehyde solution, the particle size of Ag nanoparticles reaches a minimum at the lowest pH value. The TEM observations show that Ag nanoparticles are distributed both in the exterior and interior of the grafting layer. In addition, under high pH values the distribution of the Ag nanoparticles permeate more deeply in the GMA-IDA grafting layer due to the swelling effect of the GMA-IDA polymer.

  16. Photo-Curable Metal-Chelating Coatings Offer a Scalable Approach to Production of Antioxidant Active Packaging.

    Science.gov (United States)

    Lin, Zhuangsheng; Goddard, Julie

    2018-02-01

    Synthetic metal chelators (for example, ethylenediaminetetraacetic acid, EDTA) are widely used as additives to control trace transition metal induced oxidation in consumer products. To enable removal of synthetic chelators in response to increasing consumer demand for clean label products, metal-chelating active food packaging technologies have been developed with demonstrated antioxidant efficacy in simulated food systems. However, prior work in fabrication of metal-chelating materials leveraged batch chemical reactions to tether metal-chelating ligands, a process with limited industrial translatability for large-scale fabrication. To improve the industrial translatability, we have designed a 2-step laminated photo-grafting process to introduce metal chelating functionality onto common polymeric packaging materials. Iminodiacetic acid (IDA) functionalized materials were fabricated by photo-grafting poly(acrylic acid) onto polypropylene (PP) films, followed by a second photo-grafting process to graft-polymerize an IDA functionalized vinyl monomer (GMA-IDA). The photo-grafting was conducted under atmospheric conditions and was completed in 2 min. The resulting IDA functionalized metal-chelating material was able to chelate iron and copper, and showed antioxidant efficacy against ascorbic acid degradation, supporting its potential to be used synergistically with natural antioxidants for preservation of food and beverage products. The 2-step photo-grafting process improves the throughput of active packaging coatings, enabling potential roll-to-roll fabrication of metal-chelating active packaging materials for antioxidant food packaging applications. To address consumer and retail demands for "clean label" foods and beverages without a corresponding loss in product quality and shelf life, producers are seeking next generation technologies such as active packaging. In this work, we will report the synthesis of metal-chelating active packaging films, which enable removal

  17. VIDEO CAPSULE ENDOSCOPY: A TOOL FOR THE ASSESSMENT OF SMALL BOWEL TRANSIT TIME

    Directory of Open Access Journals (Sweden)

    Reza A Hejazi

    2016-02-01

    Full Text Available Purpose: Video capsule endoscopy (VCE is a procedure that uses a wireless camera to take pictures of the gastrointestinal tract. A wireless motility capsule (WMC of a similar size has been developed, which measures pH, pressure, and temperature, and can be used to assess regional and total gastrointestinal transit times. VCE could also potentially be used as a tool for measuring small bowel transit time (SBTT.Methods: This study was designed to obtain SBTT from VCE and compare it with historical data generated by WMC. Gastric transit time (GTT was also measured. Patients were included if the indication for VCE was either iron deficiency anemia (IDA or overt obscure GI bleed (OOGIB and they did not have any known motility disorder. Results from VCE were also compared in diabetic versus non-diabetic patients. Results: There were a total of 147 VCE studies performed, including 42 for OOGIB and 105 for IDA. Median GTT and SBTT were 0.3 and 3.6 hours, respectively. The overall median GTT and SBTT were 0.3 and 3.6 hours, respectively, in the IDA group compared with 0.3 and 3.4 hours in the OOGIB group. When compared with WMC, the GTT and SBTT were significantly faster in both groups (GTT: 3.6 hours and SBTT: 4.6 hours. The median GTT and SBTT were not significantly different in diabetics versus non-diabetics: (GTT: 17.5 vs. 18.0 minutes (P=0.86 and SBTT: 3.9 hours (237 minutes vs. 3.8 hours (230 minutes, respectively (P=0.90.Conclusion: SBTT as measured using VCE is not significantly different in OOGIB compared with IDA. Both GTT and SBTT are significantly faster as assessed by VCE, which is initiated in the fasting state, compared with WMC measurement, which is initiated after a standard meal. In summary, VCE could potentially be used for measuring SBTT in the fasting state.

  18. Video Capsule Endoscopy: A Tool for the Assessment of Small Bowel Transit Time.

    Science.gov (United States)

    Hejazi, Reza A; Bashashati, Mohammad; Saadi, Mohammed; Mulla, Zuber D; Sarosiek, Irene; McCallum, Richard W; Zuckerman, Marc J

    2016-01-01

    Video capsule endoscopy (VCE) is a procedure that uses a wireless camera to take pictures of the gastrointestinal (GI) tract. A wireless motility capsule (WMC) of a similar size has been developed, which measures pH, pressure, and temperature and can be used to assess regional and total GI transit times. VCE could also potentially be used as a tool for measuring small bowel transit time (SBTT). This study was designed to obtain SBTT from VCE and compare it with historical data generated by WMC. Gastric transit time (GTT) was also measured. Patients were included if the indication for VCE was either iron deficiency anemia (IDA) or overt obscure GI bleed (OOGIB), and they did not have any known motility disorder. Results from VCE were also compared in diabetic vs. non-diabetic patients. There were a total of 147 VCE studies performed, including 42 for OOGIB and 105 for IDA. Median GTT and SBTT were 0.3 and 3.6 h, respectively. The overall median GTT and SBTT were 0.3 and 3.6 h, respectively, in the IDA group compared with 0.3 and 3.4 h in the OOGIB group. When compared with WMC, the GTT and SBTT were significantly faster in both groups (GTT: 3.6 h and SBTT: 4.6 h). The median GTT and SBTT were not significantly different in diabetics vs. non-diabetics [GTT: 17.5 vs. 18.0 min (P = 0.86) and SBTT: 3.9 h (237 min) vs. 3.8 h (230 min), respectively (P = 0.90)]. SBTT as measured using VCE is not significantly different in OOGIB compared with IDA. Both GTT and SBTT are significantly faster as assessed by VCE, which is initiated in the fasting state, compared with WMC measurement, which is initiated after a standard meal. In summary, VCE could potentially be used for measuring SBTT in the fasting state.

  19. The effects of physical separtation treatment on the removal of uranium from contaminated soils at Fernald: A bench-scale study

    International Nuclear Information System (INIS)

    Sadler, K.G.; Krstich, M.A.

    1994-01-01

    A bench-scale treatability study incorporating the use of physical separation techniques and chemical dispersants/extractants was conducted on uranium contaminated soils at the Fernald Environmental Management Project (FEMP) site. The soils contained approximately 497 and 450 milligrams per kilogram (mg/kg) of total uranium, respectively. Geotechnical characterization indicated that 77.4 and 74.6 percent of the soil was in the less that 50 micrometer (μm) size fraction for the ID-A and ID-B soils, respectively. An initial characterization effort indicated that uranium was distributed among all particle size fractions. After each soil was dispersed in water, it was noted that the uranium concentrated in the sand and clay fractions for the ID-A soil (1028 and 1475 mg kg -1 , respectively) and the clay fraction for ID-B soil (2710 mg kg -1 ). Four 1 millimolar (mM) sodium reagent solutions (sodium hydroxide, sodium carbonate, sodium bicarbonate, and a sodium citrate-bicarbonate-dithionite mixture) and potable water were evaluated for effectiveness in dispersing each soil into single grain separates and extracting total uranium from each of the resulting particle size fractions. Dilute sodium solutions were more effective than water in dispersing the soil. The use of dispersants, as compared to water, on the less than 2 mm size fraction causes a shift in the distribution of uranium out of the sand fraction and into the silt and clay fractions for ID-A soil and into the clay fraction for the ID-B soil. Attrition scrubbing tests were conducted on the less than 2 mm size fraction for the ID-A and ID-B soils using water and three alkaline extraction solutions, sodium pyrophosphate, sodium carbonate/bicarbonate, and ammonium carbonate/bicarbonate. There was little difference among the chemical extractants on their effectiveness in removing uranium from the greater than 53 μm (sand) or less than 53 μm (silt and clay) soil fraction

  20. Sõõrumaa turvaraha voolab Eestist välja / Hindrek Riikoja

    Index Scriptorium Estoniae

    Riikoja, Hindrek

    2008-01-01

    Suurärimees Urmas Sõõrumaa firma US Invest müüs veerandi Falckist G4S Balticuks muundunud turvafirmast, saadud rahast neljandiku suunab ta Ida-Euroopa kinnisvarasse ja energeetikasse. Lisa: US Invest