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Sample records for african american cancer

  1. Cancer and African Americans

    Science.gov (United States)

    ... Population Profiles > Black/African American > Cancer Cancer and African Americans African Americans have the highest mortality rate ... 65MB] At a glance – Top Cancer Sites for African Americans (2008-2012) Cancer Incidence Rates per 100, ...

  2. Cancer and the African American Experience

    Science.gov (United States)

    The first plenary of the EPEC-O (Education in Palliative and End-of-Life Care for Oncology) Self-Study: Cultural Considerations When Caring for African Americans explores the many factors that lead to inequalities in cancer care outcomes for African Americans.

  3. African American Men and Prostate Cancer

    Medline Plus

    Full Text Available ... the African-American that we treat this as what it is -- an epidemic. Winston Dyer: My introduction ... being ignorant to prostate cancer -- and not knowing what it was -- that was my first, first, first- ...

  4. Oral Cancer in African Americans: Addressing Health Disparities

    Science.gov (United States)

    Dodd, Virginia J.; Watson, Jennifer M.; Choi, Youjin; Tomar, Scott L.; Logan, Henrietta L.

    2008-01-01

    Objectives: To explore factors underlying African Americans' perceptions of oral cancer and the oral cancer exam. Study findings were used to guide development of oral cancer messages designed to increase oral cancer exams among African Americans. Methods: Focus groups were conducted to understand African Americans' attitudes and expectations…

  5. Colorectal Cancer in African Americans: An Update.

    Science.gov (United States)

    Williams, Renee; White, Pascale; Nieto, Jose; Vieira, Dorice; Francois, Fritz; Hamilton, Frank

    2016-01-01

    This review is an update to the American College of Gastroenterology (ACG) Committee on Minority Affairs and Cultural Diversity's paper on colorectal cancer (CRC) in African Americans published in 2005. Over the past 10 years, the incidence and mortality rates of CRC in the United States has steadily declined. However, reductions have been strikingly much slower among African Americans who continue to have the highest rate of mortality and lowest survival when compared with all other racial groups. The reasons for the health disparities are multifactorial and encompass physician and patient barriers. Patient factors that contribute to disparities include poor knowledge of benefits of CRC screening, limited access to health care, insurance status along with fear and anxiety. Physician factors include lack of knowledge of screening guidelines along with disparate recommendations for screening. Earlier screening has been recommended as an effective strategy to decrease observed disparities; currently the ACG and American Society of Gastrointestinal Endoscopists recommend CRC screening in African Americans to begin at age 45. Despite the decline in CRC deaths in all racial and ethnic groups, there still exists a significant burden of CRC in African Americans, thus other strategies including educational outreach for health care providers and patients and the utilization of patient navigation systems emphasizing the importance of screening are necessary. These strategies have been piloted in both local communities and Statewide resulting in notable significant decreases in observed disparities. PMID:27467183

  6. Perspectives of African Americans on Lung Cancer: A Qualitative Analysis

    OpenAIRE

    Lathan, Christopher S.; Waldman, Laura Tesler; Browning, Emily; Gagne, Joshua; Emmons, Karen

    2015-01-01

    This qualitative study suggests that African American smokers are aware of the relationship between smoking and lung cancer and are interested in smoking-cessation treatment. These data also indicate that lung cancer disparities are unlikely to be associated with differential willingness to receive care but that African Americans may perceive financial and insurance barriers to lung cancer treatment.

  7. Family Support and Colorectal Cancer Screening among Urban African Americans

    OpenAIRE

    Brittain, Kelly; Taylor, Jacquelyn Y.; Loveland-Cherry, Carol; Northouse, Laurel; Caldwell, Cleopatra H.

    2012-01-01

    Colorectal cancer (CRC) is the third leading cause of cancer death among African Americans. Less than 50% of African Americans have had CRC screening. This study examined the relationships between family support and influence, cultural identity, CRC beliefs, and a screening informed decision among 129 urban African Americans. Family support (p < .01) significantly predicted CRC beliefs and CRC beliefs significantly predicted informed decision (p < .01). Based on study results, practitioners s...

  8. African American women's perceptions of cancer clinical trials

    OpenAIRE

    Haynes-Maslow, Lindsey; Godley, Paul; DiMartino, Lisa; White, Brandolyn; Odom, Janice; Richmond, Alan; Carpenter, William

    2014-01-01

    Cancer clinical trials are important for resolving cancer health disparities for several reasons; however, clinical trial participation among African Americans is significantly lower than Caucasians. This study engaged focus groups of 82 female African American cancer survivors or cancer caregivers, including those in better resourced, more urban areas and less resourced, more rural areas. Informed by an integrated conceptual model, the focus groups examined perceptions of cancer clinical tri...

  9. African American Men and Prostate Cancer

    Medline Plus

    Full Text Available ... runs higher. We really don't know. But I would strongly suggest to the African-American that ... then my dad four months later. And then I was told by doctors that I should be ...

  10. African American Men and Prostate Cancer

    Medline Plus

    Full Text Available ... Walker: The researchers don't know exactly why. It is suggested that maybe our diet, maybe our ... African-American that we treat this as what it is -- an epidemic. Winston Dyer: My introduction to ...

  11. African American Men and Prostate Cancer

    Medline Plus

    Full Text Available ... Americans have one of the highest incidences of prostate cancer in the world, and in this country the ... is -- an epidemic. Winston Dyer: My introduction to prostate cancer started with the death of my 46-year- ...

  12. African American Men and Prostate Cancer

    Medline Plus

    Full Text Available ... Americans have one of the highest incidences of prostate cancer in the world, and in this country ... is -- an epidemic. Winston Dyer: My introduction to prostate cancer started with the death of my 46- ...

  13. African American Men and Prostate Cancer: Be Your Own Advocate and Understand Screening

    Science.gov (United States)

    AFRICAN AMERICAN MEN AND PROSTATE CANCER: BE YOUR OWN ADVOCATE AND UNDERSTAND SCREENING By the National Cancer ... American men. For reasons that are still unknown, African American men are more likely to get prostate ...

  14. Donation Intentions for Cancer Genetics Research Among African Americans

    OpenAIRE

    McDonald, Jasmine A; Weathers, Benita; Barg, Frances K.; Troxel, Andrea B; Shea, Judy A; Bowen, Deborah; Guerra, Carmen E.; Halbert, Chanita Hughes

    2012-01-01

    Aims: Scientific agencies rely on individuals to donate their DNA to support research on chronic conditions that disproportionately affect African Americans; however, donation is variable in this population. The purpose of this study was to identify sociodemographic characteristics, health care variables, and cultural values having significant independent associations with intentions to donate blood or saliva samples for cancer genetics research among African American adults. Method: Cross-se...

  15. Opportunities to address lung cancer disparities among African Americans

    OpenAIRE

    Coughlin, Steven S.; Matthews-Juarez, Patricia; Juarez, Paul D.; Melton, Courtnee E; King, Mario

    2014-01-01

    Race and socioeconomic status are well known to influence lung cancer incidence and mortality patterns in the U.S. Lung cancer incidence and mortality rates are higher among blacks than whites. In this article we review opportunities to address disparities in lung cancer incidence, mortality, and survivorship among African Americans. First, we summarize recent advances in the early detection and treatment of lung cancer. Then we consider black-white disparities in lung cancer treatment includ...

  16. African American Men and Prostate Cancer

    Medline Plus

    Full Text Available Curtis Pettaway, M.D.: We know that black Americans have one of the highest incidences of prostate cancer in the world, and in this country ... have even suggested that our testosterone runs higher. We really don't know. But I would strongly ...

  17. African American Men and Prostate Cancer

    Medline Plus

    Full Text Available Curtis Pettaway, M.D.: We know that black Americans have one of the highest incidences of prostate cancer in the world, and in ... not go to the doctor's. Curtis Pettaway, M.D.: Those are the individuals where the message really ...

  18. Knowledge and Attitudes about Colon Cancer Screening among African Americans

    Science.gov (United States)

    James, Aimee S.; Daley, Christine M.; Greiner, K. Allen

    2011-01-01

    Objectives: To explore knowledge and attitudes about colorectal cancer (CRC) screening among African American patients age 45 and older at a community health center serving low-income and uninsured patients. Methods: We conducted 7 focus groups and 17 additional semistructured interviews. Sessions were audio-recorded, transcribed, and analyzed…

  19. Fat, fibre and cancer risk in African Americans and rural Africans

    NARCIS (Netherlands)

    O'Keefe, S.J.; Li, J.V.; Lahti, Leo; Ou, J.; Carbonero, F.; Khaled, M.; Postma, J.M.; Kinross, J.; Wahl, E.; Ruder, E.; Vipperla, K.; Naidoo, V.; Mtshali, L.; Tims, S.; Puylaert, P.G.B.; DeLany, J.; Krasinskas, A.; Benefiel, A.C.; Kaseb, H.O.; Newton, K.; Nicholson, J.K.; Vos, De W.M.; Gaskins, H.R.; Zoetendal, E.G.

    2015-01-01

    Rates of colon cancer are much higher in African Americans (65:100,000) than in rural South Africans (<5:100,000). The higher rates are associated with higher animal protein and fat, and lower fibre consumption, higher colonic secondary bile acids, lower colonic short-chain fatty acid quantities and

  20. Cancer Support Needs for African American Breast Cancer Survivors and Caregivers.

    Science.gov (United States)

    Haynes-Maslow, Lindsey; Allicock, Marlyn; Johnson, La-Shell

    2016-03-01

    Improved cancer screening and treatment advances have led to higher cancer survival rates in the United States. However, racial disparities in breast cancer survival persist for African American women who experience lower survival rates than white women. These disparities suggest that unmet needs related to survivorship still exist. This study focuses on the challenges that both African American cancer survivors and caregivers face across the cancer continuum. Five African American focus groups examined cancer survivor and caregiver support needs. Focus groups were recorded, transcribed, and uploaded into Atlas.ti. Thematic content analysis was applied to the text during the coding process. Themes were identified and emphasized based on the research team's integrated and unified final codes. Forty-one African Americans participated in five focus groups: 22 cancer survivors and 19 caregivers. Participants discussed five themes: (1) a culture that discourages the discussion of cancer; (2) lack of support services for African American cancer survivors; (3) lack of support services for cancer caregivers; (4) need for culturally appropriate cancer resources, including resources targeted at African American women; and (5) aspects that were helpful to cancer survivors and caregivers, including connecting with other survivors and caregivers, and having strong social support networks. We gained new insight into the unmet support needs for survivors and caregivers, especially when coping with the cancer experience continuum. While some cancer and caregiver support services exist, our study reveals a great need for services that incorporate the cultural differences that exist across races. PMID:25869580

  1. Lifestyle Behaviors of African American Breast Cancer Survivors: A Sisters Network, Inc. Study

    OpenAIRE

    Paxton, Raheem J.; Wendell C Taylor; Shine Chang; Courneya, Kerry S.; Jones, Lovell A.

    2013-01-01

    INTRODUCTION: African American breast cancer survivors experience poor cancer outcomes that may, in part, be remedied by healthy lifestyle choices. Few studies have evaluated the health and lifestyle behaviors of this population. The purpose of this study was to characterize the health and lifestyle habits of African American breast cancer survivors and evaluate the socio-demographic and medical correlates of these behaviors. METHODS: A total of 470 African American breast cancer survivors (m...

  2. Differences in cancer incidence, mortality, and survival between African Americans and whites.

    OpenAIRE

    Walker, B.; Figgs, L.W.; Zahm, S H

    1995-01-01

    This report highlights selected evidence of different cancer patterns among African Americans and whites and considers potential risk factors associated with these cancers. During the years 1987 to 1991, African Americans experienced higher incidence and mortality rates than whites for multiple myeloma and for cancers of the oropharynx, colorectum, lung and bronchus, cervix, and prostate. African Americans had lower incidence and mortality for cancer of the urinary bladder. The incidence of b...

  3. African American Men and Prostate Cancer

    Medline Plus

    Full Text Available ... have one of the highest incidences of prostate cancer in the world, and in this country the ... an epidemic. Winston Dyer: My introduction to prostate cancer started with the death of my 46-year- ...

  4. African American Men and Prostate Cancer

    Medline Plus

    Full Text Available ... fold higher and has remained so over many years. Rev. Thomas L. Walker: The researchers don't ... cancer started with the death of my 46-year-old brother from cancer, then my dad four ...

  5. Chronic Liver Disease and African Americans

    Science.gov (United States)

    ... American > Chronic Liver Disease Chronic Liver Disease and African Americans Among African Americans, chronic liver disease is a ... white women. At a glance – Cancer Rates for African Americans (2008-2012) Cancer Incidence Rates per 100,000 – ...

  6. African American Women’s Limited Knowledge and Experiences with Genetic Counseling for Hereditary Breast Cancer

    OpenAIRE

    Sheppard, Vanessa B.; Graves, Kristi D.; Christopher, Juleen; Hurtado-de-Mendoza, Alejandra; Talley, Costellia; Williams, Karen Patricia

    2013-01-01

    Genetic counseling and testing for hereditary breast cancer have the potential benefit of early detection and early interventions in African American women. However, African American women have low use of these services compared to White women. We conducted two focus groups with African American women diagnosed with breast cancer (affected group, n=13) and women with at least one first-degree relative with breast/ovarian cancer (unaffected group, n= 8). A content analysis approach was employe...

  7. Peer navigation in African American breast cancer survivors

    Directory of Open Access Journals (Sweden)

    Mollica MA

    2014-11-01

    Full Text Available Michelle A Mollica,1 Lynne S Nemeth,1 Susan D Newman,2 Martina Mueller,1 Katherine Sterba31College of Nursing, Medical University of South Carolina, Charleston, SC, USA; 2South Carolina Clinical and Translation Research Center for Community Health Partnerships, College of Nursing, Medical University of South Carolina, Charleston, SC, USA; 3Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USAPurpose: The purpose of this study was to explore the feasibility and acceptability of a peer navigation survivorship program for African American (AA breast cancer survivors (BCS and its potential effects on selected short-term outcomes according to the Quality of Life Model Applied to Cancer Survivors.Methods: An AA BCS who completed treatment over 1 year prior to the study was trained as a peer navigator (PN, and then paired with AA women completing primary breast cancer treatment (n=4 for 2 months. This mixed-methods, proof of concept study utilized a convergent parallel approach to explore feasibility and investigate whether changes in scores are favorable using interviews and self-administered questionnaires.Results: Results indicate that the PN intervention was acceptable by both PN and BCS, and was feasible in outcomes of recruitment, cost, and time requirements. Improvements in symptom distress, perceived support from God, and preparedness for recovery outcomes were observed over time. Qualitative analysis revealed six themes emerging from BCS interviews: “learning to ask the right questions”, “start living life again”, “shifting my perspective”, “wanting to give back”, “home visits are powerful”, and “we both have a journey”: support from someone who has been there.Conclusion: Results support current literature indicating that AA women who have survived breast cancer can be an important source of support, knowledge, and motivation for those completing breast cancer treatment. Areas

  8. African American Women: Surviving Breast Cancer Mortality against the Highest Odds

    OpenAIRE

    Shelley White-Means; Muriel Rice; Jill Dapremont; Barbara Davis; Judy Martin

    2015-01-01

    Among the country’s 25 largest cities, the breast cancer mortality disparity is highest in Memphis, Tennessee, where African American women are twice as likely to die from breast cancer as White women. This qualitative study of African-American breast cancer survivors explores experiences during and post treatment that contributed to their beating the high odds of mortality. Using a semi-structured interview guide, a focus group session was held in 2012 with 10 breast cancer survivors. Themat...

  9. Breast Cancer Treatment among African American Women in North St. Louis, Missouri

    OpenAIRE

    Connors, Shahnjayla K.; Goodman, Melody S.; Noel, Lailea; Chavakula, Neeraja N.; Butler, Dwayne; Kenkel, Sandi; Oliver, Cheryl; McCullough, Isaac; Gehlert, Sarah

    2014-01-01

    Similar to disparities seen at the national and state levels, African American women in St. Louis, Missouri have higher breast cancer mortality rates than their Caucasian counterparts. We examined breast cancer treatment (regimens and timing) in a sample of African American breast cancer patients diagnosed between 2000 and 2008 while residing in a North St. Louis cluster (eight zip codes) of late stage at diagnosis. Data were obtained from medical record extractions of women participating in ...

  10. A Weight Loss Intervention for African American Breast Cancer Survivors, 2006

    OpenAIRE

    Stolley, Melinda R.; Sharp, Lisa K.; Oh, April; Schiffer, Linda

    2008-01-01

    Introduction Breast cancer survival rates are lower for African American women than for white women. Obesity, high-fat diets, and lack of regular physical activity increase risk for breast cancer recurrence, comorbid conditions, and premature death. Eighty-two percent of African American women are overweight or obese, partly because of unhealthy eating and exercise patterns. Although successful weight loss and lifestyle interventions for breast cancer survivors are documented, none has consid...

  11. Do African-American men need separate prostate cancer screening guidelines?

    OpenAIRE

    Shenoy, Divya; Packianathan, Satyaseelan; Chen, Allen M.; Vijayakumar, Srinivasan

    2016-01-01

    Background In 2012, the United States Preventative Services Task Force issued new guidelines recommending that male U.S. residents, irrespective of race, no longer be screened for prostate cancer. In African American men, the incidence of prostate cancer is almost 60 % higher and the mortality rate is two to three times greater than in Caucasians. The purpose of this study is to reduce African American men's prostate cancer burden by demonstrating they need separate screening guidelines. Meth...

  12. A comprehensive examination of breast cancer risk loci in African American women

    OpenAIRE

    Feng, Ye; Stram, Daniel O.; Rhie, Suhn Kyong; Millikan, Robert C.; Ambrosone, Christine B.; John, Esther M; Bernstein, Leslie; Zheng, Wei; Olshan, Andrew F.; Jennifer J Hu; Ziegler, Regina G.; Nyante, Sarah; Bandera, Elisa V.; Sue A Ingles; Michael F. Press

    2014-01-01

    Genome-wide association studies have identified 73 breast cancer risk variants mainly in European populations. Given considerable differences in linkage disequilibrium structure between populations of European and African ancestry, the known risk variants may not be informative for risk in African ancestry populations. In a previous fine-mapping investigation of 19 breast cancer loci, we were able to identify SNPs in four regions that better captured risk associations in African American wome...

  13. Ovarian Cancer Risk Factors in African-American and White Women

    OpenAIRE

    Moorman, Patricia G.; Palmieri, Rachel T.; Akushevich, Lucy; Berchuck, Andrew; Schildkraut, Joellen M.

    2009-01-01

    Ovarian cancer is the most lethal gynecologic malignancy in both African-American and white women. Although prevalences of many ovarian cancer risk factors differ markedly between African Americans and whites, there has been little research on how the relative contributions of risk factors may vary between racial/ethnic groups. Using data from a North Carolina case-control study (1999–2008), the authors conducted unconditional logistic regression analyses to calculate odds ratios and 95% conf...

  14. Disparities in colorectal cancer in African-Americans vs Whites: Before and after diagnosis

    Institute of Scientific and Technical Information of China (English)

    Anastasios Dimou; Kostas N Syrigos; Muhammad Wasif Saif

    2009-01-01

    There are differences between African-American and white patients with colorectal cancer, concerning their characteristics before and after diagnosis. Whites are more likely to adhere to screening guidelines. This is also the case among people with positive family history. Colorectal cancer is more frequent in Blacks. Studies have shown that that since 1985, colon cancer rates have dipped 20% to 25% for Whites, while rates have gone up for African-American men and stayed the same for African-American women. Overall, African-Americans are 38% to 43% more likely to die from colon cancer than are Whites. Furthermore, it seems that there is an African-American predominance in right-sited tumors. African Americans tend to be diagnosed at a later stage, to suffer from better differentiated tumors, and to have worse prognosis when compared with Whites. Moreover, less black patients receive adjuvant chemotherapy for resectable colorectal cancer or radiation therapy for rectal cancer. Caucasians seem to respond better to standard chemotherapy regimens than African- Americans. Concerning toxicity, it appears that patients of African-American descent are more likely to develop 5-FU toxicity than Whites, possibly because of their different dihydropyridine dehydrogenase status. Last but not least, screening surveillance seems to be higher among white than among black long-term colorectal cancer survivors. Socioeconomic and educational status account for most of these differences whereas little evidence exists for a genetic contribution in racial disparity. Understanding the nature of racial differences in colorectal cancer allows tailoring of screening and treatment interventions.

  15. Breast cancer and racial disparity between Caucasian and African American women, part 1 (BRCA-1).

    Science.gov (United States)

    Tariq, Khurram; Latif, Naeem; Zaiden, Robert; Jasani, Nick; Rana, Fauzia

    2013-08-01

    Breast cancer is a commonly diagnosed malignancy and the second leading cause of cancer-related death among American women today. Despite the lower incidence of breast cancer among African American women, they are more likely to die from the disease each year than their white counterparts. We present a retrospective cohort study of the tumor registry data from electronic medical records of patients diagnosed with breast cancer at the University of Florida Health, Jacksonville from 2000 to 2005. A total of 907 patients were diagnosed with breast cancer; 445 patients with invasive breast cancer had complete medical records and were selected for this review. Much like previously published research, we found that African American patients presented with a more advanced stage and aggressive subtype of breast cancer than white patients, and were less likely to have health insurance. However, we have yet to determine if universal health care insurance can lead to improved health care access, better breast cancer awareness, and an enhanced attitude toward breast cancer screenings. Such factors would ultimately lead to an earlier diagnosis and better outcomes in both African American and white patients. We plan to investigate this critical issue in a follow-up study (BRCA-2; Breast Cancer and Racial Disparity Between Caucasian and African American Women, Part 2), which will begin a few years after the complete implementation of the universal health care law enacted by President Obama in 2010. The higher frequency of aggressive tumor subtypes in African American women warrants more attention. We suggest further research to determine whether decreasing the initial age for screening or increasing the frequency of mammograms in African American women would improve breast cancer outcomes. This study underscores the importance of identifying and preventing obstacles in routine breast cancer screening, as well as increasing breast cancer awareness. PMID:24518421

  16. Perceived discrimination, coping, and quality of life for African-American and Caucasian persons with cancer.

    Science.gov (United States)

    Merluzzi, Thomas V; Philip, Errol J; Zhang, Zhiyong; Sullivan, Courtney

    2015-07-01

    In racial disparities research, perceived discrimination is a proposed risk factor for unfavorable health outcomes. In a proposed "threshold-constraint" theory, discrimination intensity may exceed a threshold and require coping strategies, but social constraint limits coping options for African Americans, who may react to perceived racial discrimination with disengagement, because active strategies are not viable under this social constraint. Caucasian Americans may experience less discrimination and lower social constraint, and may use more active coping strategies. There were 213 African Americans and 121 Caucasian Americans with cancer who participated by completing measures of mistreatment, coping, and quality of life. African Americans reported more mistreatment than Caucasian Americans (p ethnicity (p Discrimination may exceed threshold more often for African Americans than for Caucasians and social constraint may exert greater limits for African Americans. Results suggest that perceived discrimination affects quality of life for African Americans with cancer because their coping options to counter mistreatment, which is racially based, are limited. This process may also affect treatment, recovery, and survivorship. PMID:25090144

  17. Obesity and African Americans

    Science.gov (United States)

    ... Data > Minority Population Profiles > Black/African American > Obesity Obesity and African Americans African American women have the ... ss6304.pdf [PDF | 3.38MB] HEALTH IMPACT OF OBESITY More than 80 percent of people with type ...

  18. A review of hair product use on breast cancer risk in African American women

    OpenAIRE

    Stiel, Laura; Adkins‐Jackson, Paris B.; Clark, Phyllis; Mitchell, Eudora; Montgomery, Susanne

    2016-01-01

    Abstract The incidence rate of breast cancer for African American women has recently converged with that of non‐Hispanic White women in the United States, although African Americans have a higher mortality rate due to this disease. Although most research exploring health disparities associated with this phenomenon has focused on differences between women based on biology and behavior, both the academic and lay communities have begun to explore the potential role of environmental exposure to e...

  19. Socioeconomic Status, Negative Affect, and Modifiable Cancer Risk Factors in African American Smokers

    OpenAIRE

    Kendzor, Darla E.; Cofta-Woerpel, Ludmila M.; Mazas, Carlos A.; Li, Yisheng; Vidrine, Jennifer Irvin; Reitzel, Lorraine R.; Costello, Tracy J.; Businelle, Michael S.; Ahluwalia, Jasjit S.; Cinciripini, Paul M.; Wetter, David W.

    2008-01-01

    The purpose of the present study was to describe the prevalence, patterns, and predictors of co-occurring modifiable cancer risk factors among African Americans seeking smoking cessation treatment, and to evaluate previously hypothesized models of the relationship between socioeconomic status and health behavior. Overweight/obesity, at-risk alcohol consumption, and insufficient physical activity were measured in 399 African American smokers. Analyses indicated that 92.8% of participants had a...

  20. The utility of cancer-related cultural constructs to understand colorectal cancer screening among African Americans

    Directory of Open Access Journals (Sweden)

    Vetta L. Sanders Thompson

    2013-09-01

    Full Text Available Background. Data suggest that colorectal cancer could be cut by approximately 60% if all people aged 50 years or older received regular screening. Studies have identified socio-cultural attitudes that might inform cancer education and screening promotion campaigns. This article applies item response theory (IRT to a set of survey items selected to assess sociocultural attitudes in order to determine how current measures may affect what we know about how these attitudes affect colorectal cancer screening (CRCS.Design and Methods. A survey of colorectal cancer screening, screening attitudes and cultural beliefs was administered to 1021 African Americans – 683 women and 338 men, ages 50 to 75. Eligibility crite ria for participation included being born in the United States, self-identified African American male or female, age 50 to 75 years. The IRT analysis was performed on 655 individuals with complete data for the 43 observed variables. Results. Twenty-nine items comprise the Multi-construct African American Cultural Survey (MAACS that addresses seven cultural con- structs: mistrust/distrust, privacy, ethnic identity, collectivism, empowerment, and male gender roles. The items provide adequate information about the attitudes of the population across most levels of the constructs assessed. Among the sociocultural variables considered, empowerment (OR=1.078; 95% CI: 1.008, 1.151 had the strongest association with CRCS adherence and privacy showed promise. Conclusions. The MAACS provides a fixed length questionnaire to assess African American CRCS attitudes, two new constructs that might assist in CRCS promotion, and a suggested focus for identification of additional constructs of interest.

  1. Analysing breast cancer microarrays from African Americans using shrinkage-based discriminant analysis

    Directory of Open Access Journals (Sweden)

    Pang Herbert

    2010-10-01

    Full Text Available Abstract Breast cancer tumours among African Americans are usually more aggressive than those found in Caucasian populations. African-American patients with breast cancer also have higher mortality rates than Caucasian women. A better understanding of the disease aetiology of these breast cancers can help to improve and develop new methods for cancer prevention, diagnosis and treatment. The main goal of this project was to identify genes that help differentiate between oestrogen receptor-positive and -negative samples among a small group of African-American patients with breast cancer. Breast cancer microarrays from one of the largest genomic consortiums were analysed using 13 African-American and 201 Caucasian samples with oestrogen receptor status. We used a shrinkage-based classification method to identify genes that were informative in discriminating between oestrogen receptor-positive and -negative samples. Subset analysis and permutation were performed to obtain a set of genes unique to the African-American population. We identified a set of 156 probe sets, which gave a misclassification rate of 0.16 in distinguishing between oestrogen receptor-positive and -negative patients. The biological relevance of our findings was explored through literature-mining techniques and pathway mapping. An independent dataset was used to validate our findings and we found that the top ten genes mapped onto this dataset gave a misclassification rate of 0.15. The described method allows us best to utilise the information available from small sample size microarray data in the context of ethnic minorities.

  2. African American Participation in Oncology Clinical Trials-Focus on Prostate Cancer: Implications, Barriers, and Potential Solutions.

    Science.gov (United States)

    Ahaghotu, Chiledum; Tyler, Robert; Sartor, Oliver

    2016-04-01

    In the United States, the incidence and mortality rates of many cancers, especially prostate cancer, are disproportionately high among African American men compared with Caucasian men. Recently, mortality rates for prostate cancer have declined more rapidly in African American versus Caucasian men, but prostate cancer is still the most common cancer and the second leading cause of cancer deaths in African American men in the United States. Compared with Caucasian men, prostate cancer occurs at younger ages, has a higher stage at diagnosis, and is more likely to progress after definitive treatments in African American men. Reasons for racial discrepancies in cancer are multifactorial and potentially include socioeconomic, cultural, nutritional, and biologic elements. In addition to improving access to novel therapies, clinical trial participation is essential to adequately establish the risks and benefits of treatments in African American populations. Considering the disproportionately high mortality rates noted in these groups, our understanding of the natural history and responses to therapies is limited. This review will explore African American underrepresentation in clinical trials with a focus on prostate cancer, and potentially effective strategies to engage African American communities in prostate cancer research. Solutions targeting physicians, investigators, the community, and health care systems are identified. Improvement of African American participation in prostate cancer clinical trials will benefit all stakeholders. PMID:26786562

  3. Socioeconomic status, negative affect, and modifiable cancer risk factors in African-American smokers.

    Science.gov (United States)

    Kendzor, Darla E; Cofta-Woerpel, Ludmila M; Mazas, Carlos A; Li, Yisheng; Vidrine, Jennifer Irvin; Reitzel, Lorraine R; Costello, Tracy J; Businelle, Michael S; Ahluwalia, Jasjit S; Cinciripini, Paul M; Wetter, David W

    2008-10-01

    The purpose of the present study was to describe the prevalence, patterns, and predictors of cooccurring modifiable cancer risk factors among African-Americans seeking smoking cessation treatment and to evaluate previously hypothesized models of the relationship between socioeconomic status (SES) and health behavior. Overweight/obesity, at-risk alcohol consumption, and insufficient physical activity were measured in 399 African-American smokers. Analyses indicated that 92.8% of participants had at least one cancer risk factor in addition to smoking. Univariate ordinal logistic regression analyses revealed that female gender, unemployment, lower positive affect, and greater negative affect were associated with having a greater number of cancer risk factors. Multivariate analyses yielded similar findings. A structural equation modeling approach indicated that stress/negative affect may function as one pathway linking SES and modifiable cancer risk factors among African-American smokers and that gender has a direct effect on modifiable cancer risk factors. Thus, risk patterns identified within each gender group may guide the development of multiple risk factor interventions for African-American smokers. Stress and negative affect may be an important treatment target within behavioral interventions for African-American smokers of low SES. PMID:18842995

  4. Word on the Street: Engaging Local Leaders in a Dialogue About Prostate Cancer Among African Americans.

    Science.gov (United States)

    Schoenfeld, Elinor R; Francis, Linda E

    2016-09-01

    African American men face the highest rates of prostate cancer, yet with no consensus for screening and treatment, making informed health care decisions is difficult. This study aimed to identify approaches to empowering African American men as proactive participants in prostate cancer decision making using an established community-campus partnership employing elements of community-based participatory research methods. Community stakeholders with an interest in, and knowledge about, health care in two local African American communities were recruited and completed key informant interviews (N = 39). Grounded theory coding identified common themes related to prostate cancer knowledge, beliefs, attitudes, and responses to them. Common barriers such as gender roles, fear, and fatalism were identified as barriers to work-up and treatment, and both communities' inadequate and inaccurate prostate cancer information described as the key problem. To build on community strengths, participants said the change must come from inside these communities, not be imposed from the outside. To accomplish this, they suggested reaching men through women, connecting men to doctors they can trust, making men's cancer education part of broader health education initiatives designed as fun and inexpensive family entertainment events, and having churches bring community members in to speak on their experiences with cancer. This study demonstrated the success of community engagement to identify not only barriers but also local strengths and facilitators to prostate cancer care in two suburban/rural African American communities. Building collaboratively on community strengths may improve prostate cancer care specifically and health care in general. PMID:25595017

  5. Ring of Silence: African American Women's Experiences Related to Their Breasts and Breast Cancer Screening

    Science.gov (United States)

    Thomas, Eileen

    2006-01-01

    The purpose of this study was to explore women's memories and feelings concerning their breasts and breast cancer screening experiences in relation to their current breast cancer screening behaviors. Twelve African American women shared stories that were generated in written narratives and individual interviews. Two core themes emerged from the…

  6. Teaching strategies to facilitate breast cancer screening by African-American women.

    Science.gov (United States)

    Gibson, Lynette M

    2008-12-01

    The objective of this paper is to report on the recent literature concerning coverage of breast cancer epidemiology, the barriers to breast cancer screening, and the strategies to facilitate screening by African-American women. Based on these findings, the author suggests culturally appropriate techniques to be used to promote breast cancer screening in African-American women. Barriers to breast cancer screening in African-American women include emotional reasons, spiritual/religious reasons, fatalism, logistic concerns, lack of knowledge, and lack of follow-up by health-care professionals. Numerous strategies that have been targeted toward African-American women are reported. These include storytelling, witnessing, and testimonies; providing social support and having social support networks; and conducting multifaceted programs that include culturally specific breast health information. Based on the literature reviewed, the author suggests some examples of creative and culturally appropriate techniques that have been implemented with African-American women and that have resulted in positive feedback. These examples include the use of testimonies, photographs, prose, narratives, poetry, and quotations. PMID:19397053

  7. A Cancer Center’s Approach to Engaging African American Men About Cancer: The Men’s Fellowship Breakfast, Southeastern Michigan, 2008–2014

    OpenAIRE

    Langford, Aisha T.; Griffith, Derek M.; Beasley, Derrick D.; Braxton, Effat Id-Deen

    2014-01-01

    Background Despite disproportionate rates of cancer morbidity and mortality among African American men, few community-based efforts have been developed and sustained to educate African American men about cancer. The University of Michigan Comprehensive Cancer Center implemented a series of breakfasts to improve cancer awareness, screening, and education among African American men. This article describes the rationale for and history of the community intervention. Community Context The 21 brea...

  8. Vitamin D and Immune Response: Implications for Prostate Cancer in African Americans

    OpenAIRE

    Batai, Ken; Murphy, Adam B.; Nonn, Larisa; Kittles, Rick A.

    2016-01-01

    Prostate cancer (PCa) is the most common cancer among men in the U.S. African American (AA) men have a higher incidence and mortality rate compared to European American (EA) men, but the cause of PCa disparities is still unclear. Epidemiologic studies have shown that vitamin D deficiency is associated with advanced stage and higher tumor grade and mortality, while its association with overall PCa risk is inconsistent. Vitamin D deficiency is also more common in AAs than EAs, and the differenc...

  9. Immunizations and African Americans

    Science.gov (United States)

    ... Program Grants Other Grants Planning and Evaluation Grantee Best Practices Black/African American Asthma Cancer Chronic Liver Disease ... 13 to 17 years who ever received the human papillomavirus (HPV) vaccination, 2014 - Males # doses ... 240-453-2882 Office of Minority Health Resource Center Toll Free: 1-800-444-6472 / Fax: ...

  10. Psychosocial Influences on Suboptimal Adjuvant Breast Cancer Treatment Adherence among African American Women: Implications for Education and Intervention

    Science.gov (United States)

    Magai, Carol; Consedine, Nathan S.; Adjei, Brenda A.; Hershman, Dawn; Neugut, Alfred

    2008-01-01

    Despite lower incidence, African American women are at increased risk of dying from breast cancer relative to their European American counterparts. Although there are key differences in both screening behavior and tumor characteristics, an additional part of this mortality difference may lie in the fact that African American women receive…

  11. Increased Incidence of Loco-Regional Recurrences Among African American Women with Terminal Stage Breast Cancer

    OpenAIRE

    Gerardo Colón-Otero; Sherry King; Vandelyn Smith; Carolyn Bieber; Julia Crook; Solberg, Lawrence A.; Robert Shannon; Perez, Edith A.

    2008-01-01

    A prospective analysis of women with terminal breast cancer admitted to CHNE from November 2006-August 2007 evaluated anecdotal observations that African American (AA) women are likelier than Caucasian women to evidence loco-regional recurrences (LRR). Women with terminal breast cancer who were admitted to CHNE, a not-for-profit hospice serving over 90% of Northeast Florida hospice patients, were eligible for participation. 134 terminal breast cancer patients were assessed by hospice nurses f...

  12. Intervention Approaches for Addressing Breast Cancer Disparities among African American Women

    OpenAIRE

    Coughlin, Steven S.

    2014-01-01

    African American women in the U.S. have a higher mortality rate from breast cancer than white women. Black-white differences in survival persist even after accounting for disease stage and tumor characteristics suggesting that the higher rates of breast cancer mortality are due to social factors. Several factors may account for racial differences in breast cancer mortality including socioeconomic factors, access to screening mammography and timely treatment, and biological factors. Efforts to...

  13. Mammographic density and breast cancer risk in White and African American Women

    OpenAIRE

    Razzaghi, Hilda; Troester, Melissa A.; Gierach, Gretchen L.; Olshan, Andrew F.; Yankaskas, Bonnie C.; Millikan, Robert C.

    2012-01-01

    Mammographic density is a strong risk factor for breast cancer, but limited data are available in African American (AA) women. We examined the association between mammographic density and breast cancer risk in AA and white women. Cases (n = 491) and controls (n = 528) were from the Carolina Breast Cancer Study (CBCS) who also had mammograms recorded in the Carolina Mammography Registry (CMR). Mammographic density was reported to CMR using Breast Imaging Reporting and Data System (BI-RADS) cat...

  14. Metastatic progression and gene expression between breast cancer cell lines from African American and Caucasian women

    OpenAIRE

    Yancy Haile F; Mason Jacquline A; Peters Sharla; Thompson Charles E; Littleton George K; Jett Marti; Day Agnes A

    2007-01-01

    Abstract African American (AA) women have a lower overall incidence of breast cancer than do Caucasian (CAU) women, but a higher overall mortality. Little is known as to why the incidence of breast cancer is lower yet mortality is higher in AA women. Many studies speculate that this is only a socio-economical problem. This investigation suggests the possibility that molecular mechanisms contribute to the increased mortality of AA women with breast cancer. This study investigates the expressio...

  15. Anthropometric Changes Using a Walking Intervention in African American Breast Cancer Survivors: A Pilot Study

    Directory of Open Access Journals (Sweden)

    James Kilpatrick, PhD

    2005-03-01

    Full Text Available Introduction African American women exhibit a higher mortality rate from breast cancer than do white women. African American women are more likely to gain weight at diagnosis, which may increase their risk of cancer recurrence and comorbidities. Physical activity has been shown to decrease body mass index and improve quality of life in cancer survivors. This study was designed to evaluate the feasibility and impact of a community-based exercise intervention in African American breast cancer survivors. Methods A theory-based eight-week community intervention using pedometers with scheduling, goal setting, and self-assessment was tested in a convenience sample of African American breast cancer survivors (n = 24. Data were collected at three time points to examine changes in steps walked per day, body mass index, and other anthropometric measures, attitudes, and demographic variables. Results Statistically significant increases in steps walked per day and attitude toward exercise as well as significant decreases in body mass index, body weight, percentage of body fat, and waist, hip, and forearm circumferences, as well as blood pressure, were reported from baseline to immediate post-intervention. Positive changes were retained or improved further at three-month follow-up except for attitude toward exercise. Participant retention rate during eight-week intervention was 92%. Conclusion Increasing walking for exercise, without making other changes, can improve body mass index, anthropometric measures, and attitudes, which are associated with improved quality of life and reduced risk of cancer recurrence. The high participant retention rate, along with significant study outcomes, demonstrate that among this sample of African American breast cancer survivors, participants were motivated to improve their exercise habits.

  16. Prostate cancer screening in African American and Caribbean males: detriment in delay.

    Science.gov (United States)

    Parchment, Yvonne D

    2004-01-01

    Men of the African diaspora are diagnosed with prostate cancer much later than Caucasians and the mortality rate is significantly higher in these groups than among Caucasians. This study investigates health beliefs surrounding prostate health in a sample of African American and Caribbean men and identifies reasons men have for delaying or avoiding prostate screenings. One hundred African American and Caribbean men recruited from three churches, aged 37-89, were surveyed about their health seeking behaviors and knowledge of prostate cancer. Forty-five of these men also attended a seminar on the importance of early detection. Eighty percent of the men revealed they were embarrassed to have digital rectal examinations. Sixty percent feared impotence and incontinence after treatment if diagnosed with cancer. Findings reveal that attention to cultural realities may assist healthcare professionals in planning culturally sensitive educational interventions in the community that may narrow the health disparities gap in this population. PMID:18399361

  17. Neighborhood Satisfaction and Colorectal Cancer Screening in a Community Sample of African Americans.

    Science.gov (United States)

    Halbert, Chanita Hughes; Melvin, Cathy; Briggs, Vanessa; Delmoor, Ernestine; Rice, LaShanta J; Lynch, Cheryl; Jefferson, Melanie; Johnson, Jerry C

    2016-02-01

    Social determinants are important to cancer screening among African Americans. To evaluate the association between social determinants (e.g., psychological characteristics, perceived social environment, cultural beliefs such as present temporal orientation) and colorectal cancer (CRC) screening among African Americans. African American adults (n = 262) ages 50-75 completed a telephone interview. Multivariate logistic regression analysis was used to identify factors having significant independent associations with CRC screening. Only 57% of respondents reported having CRC screening. The likelihood of screening increased with greater neighborhood satisfaction (OR = 1.38, 95% CI = 1.01, 1.90, p = 0.04), older age (OR = 1.75, 95% CI = 1.24, 2.48, p = 0.002), greater self-efficacy (OR = 2.73, 95% CI = 1.40, 5.35, p = 0.003), and health care provider communication (OR = 10.78, 95% CI = 4.85, 29.94, p = 0.0001). Community resources are important precursors to CRC screening and outcomes among African Americans. In addition to addressing psychological factors and patient-provider communication, efforts to ensure the availability of quality health care facilities that provide CRC screening in the neighborhoods where African Americans live are needed. PMID:26184107

  18. Lifestyle behaviors of African American breast cancer survivors: a Sisters Network, Inc. study.

    Directory of Open Access Journals (Sweden)

    Raheem J Paxton

    Full Text Available INTRODUCTION: African American breast cancer survivors experience poor cancer outcomes that may, in part, be remedied by healthy lifestyle choices. Few studies have evaluated the health and lifestyle behaviors of this population. The purpose of this study was to characterize the health and lifestyle habits of African American breast cancer survivors and evaluate the socio-demographic and medical correlates of these behaviors. METHODS: A total of 470 African American breast cancer survivors (mean age = 54 years participated in an online survey. All participants completed measures assessing medical and demographic characteristics, physical activity, and sedentary behavior. Chi-square tests for association, nonparametric tests, and logistic regression models were used to assess associations. All statistical tests were two sided. RESULTS: Almost half (47% of the women met the current guidelines for physical activity, almost half (47% were obese, and many reported having high blood pressure (53% or diabetes (21%. The prevalence of high blood pressure, diabetes, and high cholesterol increased by age (P<0.001, and obese women had a higher prevalence of high blood pressure (63% vs. 44% and diabetes (21% vs. 12% than did non-obese women (all P<0.05. Obese women participated in significantly fewer total minutes of physical activity per week (100 minutes/week than did non-obese women (150 minutes/week; P<0.05. The number of comorbid conditions was associated with increased odds for physical inactivity (odds ratio = 1.40 and obesity (odds ratio = 2.22. CONCLUSION: Many African American breast cancer survivors had chronic conditions that may be exacerbated by poor lifestyle choices. Our results also provide evidence that healthy lifestyle interventions among obese African American breast cancer survivors are urgently needed.

  19. A community-based collaborative approach to improve breast cancer screening in underserved African American women.

    Science.gov (United States)

    Karcher, Rachel; Fitzpatrick, Dawn C; Leonard, Dawn J; Weber, Scott

    2014-09-01

    Although African American women in the United States have a lower incidence of breast cancer compared with white women, those younger than 40 years actually have a higher incidence rate; additionally, African American women are more likely to die from breast cancer at every age compared with white women. Racial disparities in breast cancer mortality rates are especially significant in Maryland, which ranks fifth in the nation for breast cancer mortality, and in Baltimore City, which has the second highest annual death rate for African American women in Maryland. To address this disparity in care, Med-IQ, an accredited provider of CME, collaborated with Sisters Network Baltimore Metropolitan, Affiliate Chapter of Sisters Network® Inc., the only national African American breast cancer survivorship organization, to sponsor their community-based educational outreach initiative. The collaborative mission was to engage at-risk African American women, their families, local organizations, healthcare professionals, and clinics, with the goals of increasing awareness, addressing fears that affect timely care and diagnosis, and encouraging women to obtain regular mammograms. Intervention strategies included (1) a "Survivor Stories" video, (2) patient outreach consisting of neighborhood walks and an educational luncheon, and (3) a community outreach utilizing direct mailings to local businesses, community groups, and healthcare professionals. Trusted and well-known community resources were presented as mediums to promote the initiative, yielding achievement of broader and more effective outcomes. As a result of this patient-friendly initiative, two (2) of the women who sought screening were diagnosed with breast cancer and underwent treatment. PMID:24446167

  20. A review of hair product use on breast cancer risk in African American women.

    Science.gov (United States)

    Stiel, Laura; Adkins-Jackson, Paris B; Clark, Phyllis; Mitchell, Eudora; Montgomery, Susanne

    2016-03-01

    The incidence rate of breast cancer for African American women has recently converged with that of non-Hispanic White women in the United States, although African Americans have a higher mortality rate due to this disease. Although most research exploring health disparities associated with this phenomenon has focused on differences between women based on biology and behavior, both the academic and lay communities have begun to explore the potential role of environmental exposure to estrogen and endocrine disrupting chemicals (EDCs). This study reviews the current state of the science associating one such means of exposure, hair products containing EDCs, with breast cancer risk in African American women. We found a growing body of evidence linking: (1) environmental estrogen and EDC exposures to breast cancer risk, (2) the presence of such chemicals in personal care products, including hair products, and (3) the use of certain hair products with potential breast cancer risk in African Americans. At the same time, there is also increasing concern in the lay community about this risk. These results indicate the need for additional research, and the opportunity to benefit from strategic partnerships in community-collaborative approaches in order to better understand the potential "cost of beauty." PMID:26773423

  1. Neighborhood disadvantage, physical activity barriers, and physical activity among African American breast cancer survivors

    Directory of Open Access Journals (Sweden)

    Antwan Jones

    2015-01-01

    Higher renter rates and individual barriers both contribute to lower levels of physical activity in African American breast cancer survivors. These data suggest that the potential for constant residential turnover (via rentership and perceived barriers may increase physical inactivity even where facilities may be available.

  2. Developing a Cancer Prevention Programme for African-American Daughters and Mothers

    Science.gov (United States)

    Annang, Lucy; Spencer, S. Melinda; Jackson, Dawnyéa; Rosemond, Tiara N.; Best, Alicia L.; Williams, Leah R.; Carlos, Bethany

    2015-01-01

    Objective: To describe how nominal group technique was used to inform the development of a breast and cervical cancer awareness programme for African-American adult daughters and mothers. Design: A qualitative approach using nominal group technique. Setting: A mid-sized city in the Southern USA. Method: Nominal group technique was used with 30…

  3. Heart Disease and African Americans

    Science.gov (United States)

    ... Minority Population Profiles > Black/African American > Heart Disease Heart Disease and African Americans Although African American adults are ... were 30 percent more likely to die from heart disease than non-Hispanic whites. African American women are ...

  4. Infant Mortality and African Americans

    Science.gov (United States)

    ... African American > Infant Heath & Mortality Infant Mortality and African Americans African Americans have 2.2 times the infant mortality rate ... birthweight as compared to non-Hispanic white infants. African Americans had almost twice the sudden infant death syndrome ...

  5. The Impact of African American Race on Patterns of Care and Outcome in Prostate Cancer

    OpenAIRE

    Mahal, Brandon A

    2015-01-01

    Objectives: We evaluated whether African Americans (AA) with intermediate to high-risk prostate cancer receive similar treatment as white patients and whether any observed disparities are persistent with time, across age groups, or by insurance status. Methods: We used the Surveillance, Epidemiology, and End Results (SEER) database to identify 128,189 men with localized intermediate to high-risk prostate cancer (PSA >= 10 or Gleason >= 7 or T stage >= T2b) diagnosed from 2004 – 20...

  6. Neighborhood disadvantage, physical activity barriers, and physical activity among African American breast cancer survivors

    OpenAIRE

    Antwan Jones; Paxton, Raheem J.

    2015-01-01

    In view of evidence that African American cancer survivors experience the greatest challenges in maintaining adequate levels of physical activity, this cross-sectional study was designed to determine whether individual and residential environment characteristics are associated with physical activity in this population. A total of 275 breast cancer survivors completed self-report items measuring sociodemographic variables, physical activity, and select barriers to physical activity in Spring o...

  7. Fine-mapping of breast cancer susceptibility loci characterizes genetic risk in African Americans

    OpenAIRE

    Chen, Fang; Chen, Gary K.; Millikan, Robert C.; John, Esther M; Ambrosone, Christine B.; Bernstein, Leslie; Zheng, Wei; Jennifer J Hu; Ziegler, Regina G.; Deming, Sandra L.; Bandera, Elisa V.; Nyante, Sarah; Palmer, Julie R.; Rebbeck, Timothy R.; Sue A Ingles

    2011-01-01

    Genome-wide association studies (GWAS) have revealed 19 common genetic variants that are associated with breast cancer risk. Testing of the index signals found through GWAS and fine-mapping of each locus in diverse populations will be necessary for characterizing the role of these risk regions in contributing to inherited susceptibility. In this large study of breast cancer in African-American women (3016 cases and 2745 controls), we tested the 19 known risk variants identified by GWAS and re...

  8. Mental Health and African Americans

    Science.gov (United States)

    ... Program Grants Other Grants Planning and Evaluation Grantee Best Practices Black/African American Asthma Cancer Chronic Liver Disease Diabetes Heart Disease Hepatitis HIV/AIDS Immunizations Infant Heath & Mortality Mental Health Obesity Organ and Tissue Donation Stroke Stay Connected ...

  9. African Americans and Glaucoma

    Science.gov (United States)

    ... Involved News About Us Donate In This Section African Americans and Glaucoma email Send this article to ... glaucoma is the leading cause of blindness in African Americans. Half of those with glaucoma don't ...

  10. Diabetes in African Americans

    OpenAIRE

    Marshall, M.

    2005-01-01

    African Americans have a high risk for type 2 diabetes. Genetic traits, the prevalence of obesity, and insulin resistance all contribute to the risk of diabetes in the African American community. African Americans have a high rate of diabetic complications, because of poor glycaemic control and racial disparities in health care in the USA. African Americans with diabetes may have an atypical presentation that simulates type 1 diabetes, but then their subsequent clinical course is typical of t...

  11. African American Suicide

    Science.gov (United States)

    African American Suicide Fact Sheet Based on 2012 Data (2014) Overview • In 2012, 2,357 African Americans completed suicide in the U.S. Of these, ... 46 per 100,000. • The suicide rate for African Americans ages 10-19 was 2.98 per ...

  12. Breast Cancer Surgery Decision-Making and African-American Women.

    Science.gov (United States)

    Schubart, Jane R; Farnan, Michelle A; Kass, Rena B

    2015-09-01

    Prior research has used focus group methodology to investigate cultural factors impacting the breast cancer experience of women of various ethnicities including African-Americans; however, this work has not specifically addressed treatment decision-making. This study identifies key issues faced by African-American women diagnosed with breast cancer regarding treatment decisions. We used an interpretive-descriptive study design based on qualitative data from three focus groups (n = 14) representing a population of African-American women in central Pennsylvania. Participants were asked to think back to when they were diagnosed with breast cancer and their visit with the breast surgeon. Questions were asked about the actual visit, treatment choices offered, sources of information, and whether the women felt prepared for the surgery and subsequent treatments. The prompts triggered memories and encouraged open discussion. The most important themes identified were fear across the breast cancer disease trajectory, a preference for visual information for understanding the diagnosis and surgical treatment, and support systems relying on family and friends, rather than the formal health-care system. Our results have implications for practice strategies and development of educational interventions that will help breast cancer patients better understand their diagnosis and treatment options, encourage their participation in treatment decision-making, and provide psychosocial support for those at high risk for emotional distress. PMID:25200948

  13. Beliefs and Behaviors about Breast Cancer Recurrence Risk Reduction among African American Breast Cancer Survivors

    Directory of Open Access Journals (Sweden)

    Benjamin Ansa

    2015-12-01

    Full Text Available A growing body of evidence suggests that breast cancer recurrence risk is linked to lifestyle behaviors. This study examined correlations between breast cancer recurrence, risk reduction beliefs, and related behaviors among African American breast cancer survivors (AA BCSs. Study participants included 191 AA BCSs, mean age = 56.3 years, who completed a lifestyle assessment tool. Most respondents believed that being overweight (52.7%, lack of physical activity (48.7%, and a high fat diet (63.2% are associated with breast cancer recurrence. Over 65% considered themselves overweight; one third (33.5% agreed that losing weight could prevent recurrence, 33.0% disagreed, while the remaining 33.5% did not know; and nearly half (47.9% believed that recurrence could be prevented by increasing physical activity. Almost 90% survivors with BMI < 25 Kg/M2 reported no recurrence compared to 75.7% with BMI ≥ 25 Kg/M2 (p = 0.06; nearly all of the women (99.2% answered “yes” to seeking professional help to lose weight, 79.7% of which were recurrence-free (p = 0.05. These results provide information about AA BCSs’ beliefs and behaviors protective against breast cancer recurrence. Additional research is warranted to determine the effectiveness of educational interventions for AA BCSs that promote consumption of a healthy diet and engaging in regular physical activity.

  14. Epidemiology, pathology, and genetics of prostate cancer among African Americans compared with other ethnicities.

    Science.gov (United States)

    Williams, Heinric; Powell, Isaac J

    2009-01-01

    Prostate cancer is the most common cancer affecting men in the Western world. In the United States, it is the second leading cause of cancer related deaths after lung and bronchus carcinoma. No definitive causes of prostate cancer (PCa) have been identified to date but, increasing age, a positive family history, and sub-Saharan African ancestry are strongly linked to its development. African American men (AAM) have the highest reported incidence rates in the United States and their mortality from the disease is markedly higher than that of European American men (EAM). Conversely, Asian American men and Pacific Islanders (API), American Indian and Alaskan Native (AI/AN) men, and Hispanic men all have lower incidence and mortality rates as compared with EAM. The reasons for these differences are unclear. However, it is clear that AAM have more advanced PCa when diagnosed. Several other reasons have been suggested and these include differences in treatments and health seeking behavior among the ethnic groups, cultural beliefs, environmental/lifestyle factors, dietary and genetic factors. In conclusion, there are multiple factors that impact prostate cancer outcome and that may be responsible for ethnic disparity. These factors are discussed in this chapter. PMID:19107447

  15. EphB2 SNPs and Sporadic Prostate Cancer Risk in African American Men

    OpenAIRE

    Christiane M Robbins; Stanley Hooker; Kittles, Rick A.; John D. Carpten

    2011-01-01

    The EphB2 gene has been implicated as a tumor suppressor gene somatically altered in both prostate cancer (PC) and colorectal cancer. We have previously shown an association between an EphB2 germline nonsense variant and risk of familial prostate cancer among African American Men (AAM). Here we set out to test the hypothesis that common variation within the EphB2 locus is associated with increased risk of sporadic PC in AAM. We genotyped a set of 341 single nucleotide polymorphisms (SNPs) enc...

  16. Replication of Breast Cancer Susceptibility Loci in Whites and African Americans Using a Bayesian Approach

    OpenAIRE

    O'Brien, Katie M.; Cole, Stephen R.; Poole, Charles; Bensen, Jeannette T.; Herring, Amy H.; Engel, Lawrence S.; Millikan, Robert C.

    2013-01-01

    Genome-wide association studies (GWAS) and candidate gene analyses have led to the discovery of several dozen genetic polymorphisms associated with breast cancer susceptibility, many of which are considered well-established risk factors for the disease. Despite attempts to replicate these same variant-disease associations in African Americans, the evaluable populations are often too small to produce precise or consistent results. We estimated the associations between 83 previously identified ...

  17. African American Women: Surviving Breast Cancer Mortality against the Highest Odds

    Science.gov (United States)

    White-Means, Shelley; Rice, Muriel; Dapremont, Jill; Davis, Barbara; Martin, Judy

    2015-01-01

    Among the country’s 25 largest cities, the breast cancer mortality disparity is highest in Memphis, Tennessee, where African American women are twice as likely to die from breast cancer as White women. This qualitative study of African-American breast cancer survivors explores experiences during and post treatment that contributed to their beating the high odds of mortality. Using a semi-structured interview guide, a focus group session was held in 2012 with 10 breast cancer survivors. Thematic analysis and a deductive a priori template of codes were used to analyze the data. Five main themes were identified: family history, breast/body awareness and preparedness to manage a breast cancer event, diagnosis experience and reaction to the diagnosis, family reactions, and impact on life. Prayer and family support were central to coping, and survivors voiced a cultural acceptance of racial disparities in health outcomes. They reported lack of provider sensitivity regarding pain, financial difficulties, negative responses from family/friends, and resiliency strategies for coping with physical and mental limitations. Our research suggested that a patient-centered approach of demystifying breast cancer (both in patient-provider communication and in community settings) would impact how women cope with breast cancer and respond to information about its diagnosis. PMID:26703655

  18. African American Women: Surviving Breast Cancer Mortality against the Highest Odds.

    Science.gov (United States)

    White-Means, Shelley; Rice, Muriel; Dapremont, Jill; Davis, Barbara; Martin, Judy

    2016-01-01

    Among the country's 25 largest cities, the breast cancer mortality disparity is highest in Memphis, Tennessee, where African American women are twice as likely to die from breast cancer as White women. This qualitative study of African-American breast cancer survivors explores experiences during and post treatment that contributed to their beating the high odds of mortality. Using a semi-structured interview guide, a focus group session was held in 2012 with 10 breast cancer survivors. Thematic analysis and a deductive a priori template of codes were used to analyze the data. Five main themes were identified: family history, breast/body awareness and preparedness to manage a breast cancer event, diagnosis experience and reaction to the diagnosis, family reactions, and impact on life. Prayer and family support were central to coping, and survivors voiced a cultural acceptance of racial disparities in health outcomes. They reported lack of provider sensitivity regarding pain, financial difficulties, negative responses from family/friends, and resiliency strategies for coping with physical and mental limitations. Our research suggested that a patient-centered approach of demystifying breast cancer (both in patient-provider communication and in community settings) would impact how women cope with breast cancer and respond to information about its diagnosis. PMID:26703655

  19. African American Women: Surviving Breast Cancer Mortality against the Highest Odds

    Directory of Open Access Journals (Sweden)

    Shelley White-Means

    2015-12-01

    Full Text Available Among the country’s 25 largest cities, the breast cancer mortality disparity is highest in Memphis, Tennessee, where African American women are twice as likely to die from breast cancer as White women. This qualitative study of African-American breast cancer survivors explores experiences during and post treatment that contributed to their beating the high odds of mortality. Using a semi-structured interview guide, a focus group session was held in 2012 with 10 breast cancer survivors. Thematic analysis and a deductive a priori template of codes were used to analyze the data. Five main themes were identified: family history, breast/body awareness and preparedness to manage a breast cancer event, diagnosis experience and reaction to the diagnosis, family reactions, and impact on life. Prayer and family support were central to coping, and survivors voiced a cultural acceptance of racial disparities in health outcomes. They reported lack of provider sensitivity regarding pain, financial difficulties, negative responses from family/friends, and resiliency strategies for coping with physical and mental limitations. Our research suggested that a patient-centered approach of demystifying breast cancer (both in patient-provider communication and in community settings would impact how women cope with breast cancer and respond to information about its diagnosis.

  20. UNDERSTANDING THE BREAST CANCER EXPERIENCE OF WOMEN: A QUALITATIVE STUDY OF AFRICAN AMERICAN, ASIAN AMERICAN, LATINA AND CAUCASIAN CANCER SURVIVORS

    OpenAIRE

    Ashing-Giwa, Kimlin Tam; PADILLA, GERALDINE; TEJERO, JUDITH; KRAEMER, JANET; Wright, Karen; Coscarelli, Anne; Clayton, Sheila; WILLIAMS, IMANI; HILLS, DAWN

    2004-01-01

    Breast cancer is the most common form of cancer in American women across most ethnic groups. Although the psychosocial impact of breast cancer is being studied, there is little information on women from diverse ethnic and socioeconomic backgrounds.

  1. What we thought we knew: African American males' perceptions of prostate cancer and screening methods.

    Science.gov (United States)

    Clarke-Tasker, Veronica A; Wade, Revia

    2002-01-01

    This study applied the Health Belief Model in determining African American male's knowledge, attitudes and perceptions of prostate cancer and early detection methods. The ultimate value of the information assessed from this population was used to design specific theory-based, culturally relevant interventions which may decrease mortality in this high-risk population. Two focus groups were conducted with African-American men whose ages ranged from 38-80 years. After consenting to audio-taping, participants completed a survey questionnaire and viewed a culturally appropriate video on prostate cancer. Results indicate that, on average, the men believed in the efficacy of prostate cancer early detection methods. Study participants felt physicians did not adequately screen or suggest that they be screened for prostate cancer. Men between 40 and 50 years of age expressed concern about possible changes in their sex life if diagnosed with prostate cancer. Despite having limited knowledge of prostate cancer they considered a digital rectal examination to be embarrassing and uncomfortable. However, they were not opposed to having the procedure done. PMID:12108141

  2. Religiosity and physical and emotional functioning among African American and White colorectal and lung cancer patients.

    Science.gov (United States)

    Holt, Cheryl L; Oster, Robert A; Clay, Kimberly S; Urmie, Julie; Fouad, Mona

    2011-01-01

    The literature suggests that religiosity helps cope with illness. The present study examined the role of religiosity in functioning among African Americans and Whites with a cancer diagnosis. Patients were recruited from an existing study and mailed a religiosity survey. Participants (N = 269; 36% African American, 56% women) completed the mail survey, and interview data from the larger cohort was utilized in the analysis. Multivariate analyses indicated that in the overall sample religious behaviors were marginally and positively associated with mental health and negatively with depressive symptoms. Among women, religious behaviors were positively associated with mental health and negatively with depressive symptoms. Religiosity was not a predictor of study outcomes for men. Among African Americans, religious behaviors were positively associated with mental health and vitality. Among Whites, religious behaviors were negatively associated with depressive symptoms. These findings suggest a mixed role of religious involvement in cancer outcomes. The current findings may have applied potential in the areas of emotional functioning and depression. PMID:21966724

  3. Replication of GWAS hits by race for breast and prostate cancers in European Americans and African Americans

    Directory of Open Access Journals (Sweden)

    Jill Suzanne Barnholtz-Sloan

    2011-07-01

    Full Text Available In this study, we assessed association of GWAS hits by race with adjustment for potential population stratification (PS in two large, diverse study populations; the Carolina Breast Cancer Study (CBCS (N total = 3693 individuals and the University of Pennsylvania Study of Clinical Outcomes, Risk and Ethnicity (SCORE (N total = 1135 individuals. In both study populations, 136 ancestry information markers and GWAS hits (CBCS: FGFR2, 8q24; SCORE: JAZF1, MSMB, 8q24 were genotyped. Principal component analysis was used to assess ancestral differences by race. Multivariable unconditional logistic regression was used to assess differences in cancer risk with and without adjustment for the first ancestral principal component (PC1 and for an interaction effect between PC1 and the GWAS hit (SNP of interest. PC1 explained 53.7% of the variance for CBCS and 49.5% of the variance for SCORE. European Americans and African Americans were similar in their ancestral structure between CBCS and SCORE and cases and controls were well matched by ancestry. In the CBCS European Americans, 9/11 SNPs were significant after PC1 adjustment, but after adjustment for the PC1 by SNP interaction effect, only one SNP remained significant (rs1219648 in FGFR2; for CBCS African Americans , 6/11 SNPs were significant after PC1 adjustment and after adjustment for the PC1 by SNP interaction effect, all 6 SNPs remained significant and an additional SNP now became significant. In the SCORE European Americans, 0/9 SNPs were significant after PC1 adjustment and no changes were seen after additional adjustment for the PC1 by SNP interaction effect; for SCORE African Americans , 2/9 SNPs were significant after PC1 adjustment and after adjustment for the PC1 by SNP interaction effect, only one SNP remained significant (rs16901979 at 8q24. We show that genetic associations by race are modified by interaction between individual SNPs and population stratification.

  4. Renal cell cancer among African Americans: an epidemiologic review

    Directory of Open Access Journals (Sweden)

    Lipworth Loren

    2011-04-01

    Full Text Available Abstract Incidence rates for renal cell cancer, which accounts for 85% of kidney cancers, have been rising more rapidly among blacks than whites, almost entirely accounted for by an excess of localized disease. This excess dates back to the 1970s, despite less access among blacks to imaging procedures in the past. In contrast, mortality rates for this cancer have been virtually identical among blacks and whites since the early 1990s, despite the fact that nephrectomy rates, regardless of stage, are lower among blacks than among whites. These observations suggest that renal cell cancer may be a less aggressive tumor in blacks. We have reviewed the epidemiology of renal cell cancer, with emphasis on factors which may potentially play a role in the observed differences in incidence and mortality patterns of renal cell cancer among blacks and whites. To date, the factors most consistently, albeit modestly, associated with increased renal cell cancer risk in epidemiologic studies among whites - obesity, hypertension, cigarette smoking - likely account for less than half of these cancers, and there is virtually no epidemiologic evidence in the literature pertaining to their association with renal cell cancer among blacks. There is a long overdue need for detailed etiologic cohort and case-control studies of renal cell cancer among blacks, as they now represent the population at highest risk in the United States. In particular, investigation of the influence on renal cell cancer development of hypertension and chronic kidney disease, both of which occur substantially more frequently among blacks, is warranted, as well as investigations into the biology and natural history of this cancer among blacks.

  5. Cigarette smoking, cytochrome P4501A1 polymorphisms, and breast cancer among African-American and white women

    OpenAIRE

    Li, Yu; Millikan, Robert C.; Bell, Douglas A.; Cui, Lisa; Tse, Chiu-Kit J; Newman, Beth; Conway, Kathleen

    2004-01-01

    Introduction Previous epidemiologic studies suggest that women with variant cytochrome P4501A1 (CYP1A1) genotypes who smoke cigarettes are at increased risk for breast cancer. Methods We evaluated the association of breast cancer with CYP1A1 polymorphisms and cigarette smoking in a population-based, case–control study of invasive breast cancer in North Carolina. The study population consisted of 688 cases (271 African Americans and 417 whites) and 702 controls (285 African Americans and 417 w...

  6. Refining the use of cancer-related cultural constructs with African Americans.

    Science.gov (United States)

    Sanders Thompson, Vetta L; Lewis, Tanisha; Williams, Sha-Lai

    2013-01-01

    An important step in using culture to increase colorectal cancer screening is the development and use of a reliable and valid measure. Measurement items that work well are defined as those that use clear and simple language, do not result in significant missing data, do not yield unexpected frequencies or patterns of association, and capture an important component of the underlying construct. The authors' work to develop such a measure includes cognitive response testing. This article describes 41 African American participants' reactions to and processing of items that have been used in the public health literature to assess cultural attitudes believed to be relevant to colorectal cancer screening. Participants were asked to verbalize thoughts, feelings, interpretations, and ideas that came to mind while examining or responding to 10 to 11 survey items. The results of cognitive response testing suggest negative reactions to items addressing the fatalism construct, concerns about appearing racist when responding to discrimination and mistrust items, and resistance to phrasing or terminology that conveys negative attitudes or frames of reference. When items were framed in a positive way, participants reported less frustration, confusion, and concern for how they would be perceived by others. The responses of older African Americans in this sample were consistent with research previously completed by Pasick et al.; participants questioned the relevance of items related to cultural constructs to health and cancer preventive behaviors. Recommendations for the assessment and use of cultural constructs and items assessing constructs are provided. PMID:21460257

  7. Associations between Trans Fatty Acid Consumption and Colon Cancer among Whites and African Americans in the North Carolina Colon Cancer Study I

    OpenAIRE

    Vinikoor, Lisa C.; Satia, Jessie A.; Schroeder, Jane C.; Millikan, Robert C.; Martin, Christopher F.; Ibrahim, Joseph; Sandler, Robert S.

    2009-01-01

    Disparities in incidence and mortality rates of colon cancer exist between Whites and African Americans. Prior studies examined the association between trans fatty acid consumption and colorectal cancer, but none assessed this possible relationship within a large study population of African Americans and Whites. Using data from a population-based case-control study in North Carolina, we investigated this association with attention to possible racial differences. Cases and matched controls wer...

  8. Real-time moment-to-moment emotional responses to narrative and informational breast cancer videos in African American women

    OpenAIRE

    Bollinger, Sarah; Kreuter, Matthew W.

    2012-01-01

    In a randomized experiment using moment-to-moment audience analysis methods, we compared women’s emotional responses with a narrative versus informational breast cancer video. Both videos communicated three key messages about breast cancer: (i) understand your breast cancer risk, (ii) talk openly about breast cancer and (iii) get regular mammograms. A community-based convenience sample of African American women (n = 59) used a hand-held audience response device to report the intensity of thei...

  9. Knowledge, beliefs and barriers associated with prostate cancer prevention and screening behaviors among African-American men.

    Science.gov (United States)

    Blocker, Deborah E; Romocki, LaHoma Smith; Thomas, Kamilah B; Jones, Belinda L; Jackson, Ethel Jean; Reid, LaVerne; Campbell, Marci K

    2006-08-01

    African-American men have the highest prostate cancer rates worldwide, and innovative efforts are needed to increase cancer prevention and screening behaviors among this population. Formative research was conducted to assess attitudes and behaviors linked to prostate cancer prevention activities that could be used to develop a culturally relevant intervention for an African-American church-based population. Four gender-specific focus groups were conducted with 29 men and women at two African-American churches in central North Carolina. Three primary themes emerged from the focus group discussions: culturally and gender-influenced beliefs and barriers about cancer prevention and screening; barriers related to the healthcare system: and religious influences, including the importance of spiritual beliefs and church support. These discussions revealed the importance of the black family, the positive influence of spouses/partners on promoting cancer screening and healthy behaviors, the roles of faith and church leadership, and beliefs about God's will for good health. These findings also revealed that there are still major barriers and challenges to cancer prevention among African Americans, including continued mistrust of the medical community and negative attitudes toward specific screening tests. Findings provide important insights to consider in implementing successful prostate cancer prevention interventions designed for church-based audiences. PMID:16916126

  10. A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men

    Directory of Open Access Journals (Sweden)

    Gyorgy Petrovics

    2015-12-01

    Full Text Available Evaluation of cancer genomes in global context is of great interest in light of changing ethnic distribution of the world population. We focused our study on men of African ancestry because of their disproportionately higher rate of prostate cancer (CaP incidence and mortality. We present a systematic whole genome analyses, revealing alterations that differentiate African American (AA and Caucasian American (CA CaP genomes. We discovered a recurrent deletion on chromosome 3q13.31 centering on the LSAMP locus that was prevalent in tumors from AA men (cumulative analyses of 435 patients: whole genome sequence, 14; FISH evaluations, 101; and SNP array, 320 patients. Notably, carriers of this deletion experienced more rapid disease progression. In contrast, PTEN and ERG common driver alterations in CaP were significantly lower in AA prostate tumors compared to prostate tumors from CA. Moreover, the frequency of inter-chromosomal rearrangements was significantly higher in AA than CA tumors. These findings reveal differentially distributed somatic mutations in CaP across ancestral groups, which have implications for precision medicine strategies.

  11. Prostate cancer in African-American men: outcome following radiation therapy with or without adjuvant androgen ablation

    International Nuclear Information System (INIS)

    Purpose: To compare the outcome of irradiated clinically localized prostate cancer in African-American and white patients. Methods and Materials: This was a retrospective review of 1,201 men, 116 African-American and 1,085 white, with T1-T3, N0/NX, M0 prostate cancer receiving external radiation between 1987 and 1996. Pretreatment characteristics, treatment parameters, and outcome (relapse or rising prostate-specific antigen [PSA] levels, local recurrence, metastatic relapse, and survival) were compared between the groups using univariate and multivariate statistical methods. Results: There were no significant differences between African-American and white patients in T-stage, Gleason score, prostatic acid phosphatase (PAP) level, and testosterone level. African-Americans had a significantly lower incidence of abnormal digital rectal findings and a proportionally higher incidence of obstructive urinary symptoms at presentation and tended to be somewhat younger. A major difference between the two groups was in the significantly higher PSA levels among African-Americans (median, 14 ng/ml) than among white patients (median, 9.5 ng/ml). This translated into a higher incidence of unfavorable disease according to our criteria (39% vs. 25%) among African-Americans and, thus, to the more frequent use of adjuvant androgen ablation and to somewhat higher radiation doses in these patients. With a median follow-up of 42 months the overall 6-year freedom from relapse for African-Americans was 63% compared to 61% for whites (p = 0.634). We found no significant differences in biochemical relapse rates between any subgroups of African-Americans and whites. Specifically, even patients who did not have androgen ablation, when stratified by PSA levels, had similar outcomes regardless of race. Likewise, local recurrence and metastasis rates were not significantly different between the two groups. Conclusions: Although African-American patients tend to have higher pretreatment PSA

  12. A case-control analysis of smoking and breast cancer in African American women: findings from the AMBER Consortium.

    Science.gov (United States)

    Park, Song-Yi; Palmer, Julie R; Rosenberg, Lynn; Haiman, Christopher A; Bandera, Elisa V; Bethea, Traci N; Troester, Melissa A; Viscidi, Emma; Kolonel, Laurence N; Olshan, Andrew F; Ambrosone, Christine B

    2016-06-01

    Recent population studies suggest a role of smoking in the etiology of breast cancer, but few have been conducted among African American women. In a collaborative project of four large studies, we examined associations between smoking measures and breast cancer risk by menopause and hormone receptor status [estrogen receptor-positive (ER+), ER-negative (ER-) and triple-negative (ER-, PR-, HER2-)]. The study included 5791 African American women with breast cancer and 17376 African American controls. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated in multivariable logistic regression analysis with adjustment for study and risk factors. Results differed by menopausal status. Among postmenopausal women, positive associations were observed for long duration and greater pack-years of smoking: relative to never smoking, fully adjusted ORs were 1.14 (95% CI: 1.03-1.26) for duration ≥20 years and 1.16 (95% CI: 1.01-1.33) for ≥20 pack-years. By contrast, inverse associations were observed among premenopausal women, with ORs of 0.80 (95% CI: 0.68-95) for current smoking and 0.81 (95% CI: 0.69-0.96) for former smoking, without trends by duration. Associations among postmenopausal women were somewhat stronger for ER+ breast cancer. The findings suggest that the relation of cigarette smoking to breast cancer risk in African American women may vary by menopausal status and breast cancer subtype. PMID:27207658

  13. Fine mapping of chromosome 15q25.1 lung cancer susceptibility in African-Americans.

    Science.gov (United States)

    Hansen, Helen M; Xiao, Yuanyuan; Rice, Terri; Bracci, Paige M; Wrensch, Margaret R; Sison, Jennette D; Chang, Jeffery S; Smirnov, Ivan V; Patoka, Joseph; Seldin, Michael F; Quesenberry, Charles P; Kelsey, Karl T; Wiencke, John K

    2010-09-15

    Several genome-wide association studies identified the chr15q25.1 region, which includes three nicotinic cholinergic receptor genes (CHRNA5-B4) and the cell proliferation gene (PSMA4), for its association with lung cancer risk in Caucasians. A haplotype and its tagging single nucleotide polymorphisms (SNPs) encompassing six genes from IREB2 to CHRNB4 were most strongly associated with lung cancer risk (OR = 1.3; P < 10(-20)). In order to narrow the region of association and identify potential causal variations, we performed a fine-mapping study using 77 SNPs in a 194 kb segment of the 15q25.1 region in a sample of 448 African-American lung cancer cases and 611 controls. Four regions, two SNPs and two distinct haplotypes from sliding window analyses, were associated with lung cancer. CHRNA5 rs17486278 G had OR = 1.28, 95% CI 1.07-1.54 and P = 0.008, whereas CHRNB4 rs7178270 G had OR = 0.78, 95% CI 0.66-0.94 and P = 0.008 for lung cancer risk. Lung cancer associations remained significant after pack-year adjustment. Rs7178270 decreased lung cancer risk in women but not in men; gender interaction P = 0.009. For two SNPs (rs7168796 A/G and rs7164594 A/G) upstream of PSMA4, lung cancer risks for people with haplotypes GG and AA were reduced compared with those with AG (OR = 0.56, 95% CI 0.38-0.82; P = 0.003 and OR = 0.73, 95% CI 0.59-0.90, P = 0.004, respectively). A four-SNP haplotype spanning CHRNA5 (rs11637635 C, rs17408276 T, rs16969968 G) and CHRNA3 (rs578776 G) was associated with increased lung cancer risk (P = 0.002). The identified regions contain SNPs predicted to affect gene regulation. There are multiple lung cancer risk loci in the 15q25.1 region in African-Americans. PMID:20587604

  14. Engaging African Americans in developing an intervention to reduce breast cancer recurrence: A brief report

    Science.gov (United States)

    Smith, Selina A.; Whitehead, Mary S.; Sheats, Joyce Q.; Fontenot, Brittney; Alema-Mensah, Ernest; Ansa, Benjamin

    2016-01-01

    Background To develop a culturally appropriate lifestyle intervention, involvement of its intended users is needed. Methods Members of an African American (AA) breast cancer support group participated in two 4-hour guided discussions, which were audiotaped, transcribed, and analyzed to guide the content. Results The support group collaborated with researchers to develop 24 experiential nutrition education sessions using a social cognitive framework and incorporating self-regulation skills (goal-setting, self-monitoring, problem-solving, stimulus control) and social support to enhance self-efficacy for changes in dietary intake. Conclusions Community engagement fostered autonomy, built collaboration, and enhanced the capacity of AA breast cancer survivors to participate in developing a lifestyle intervention.

  15. Breast cancer knowledge, attitudes, and screening behaviors among African American women: the Black cosmetologists promoting health program

    Directory of Open Access Journals (Sweden)

    Weldon Rai-nesha

    2007-04-01

    Full Text Available Abstract Background African American women have higher rates of breast cancer mortality than their white counterparts. Studies have suggested that this is partly caused by discovery of cancer at a later stage, highlighting the importance of encouraging early detection of breast cancer in this population. To guide the creation of a breast cancer education intervention and help focus other health educators' and clinicians' health promotion efforts, this study explored whether a cohort of African American women living in San Diego would demonstrate the possession of adequate baseline knowledge about breast cancer screening and adherence to widely recommended screening guidelines. Methods African American women (N = 1,055 from San Diego, California participated in a beauty salon-based survey about breast cancer knowledge, attitudes, and screening practices. Women's ages ranged from 20 to 94 years, with average age of 42.20 (SD = 13.53 years. Thirty-four percent reported completing college and/or some graduate school training, and 52% reported having some college or post high school formal training. Seventy-five percent of the sample reported working outside their home. Participating cosmetologists and their salons were recruited to the study through word-of-mouth referral by highly respected African American community leaders. Results Salon clients reported low rates of adherence to recommended breast cancer screening guidelines. Of the 1,055 participants, 31% reporting performing breast self-exam every month. Of those participants 40 and older, 57% reported having had a clinical breast exam and 43% reported having had a mammogram in the past year. Knowledge of breast cancer was associated with adherence to screening guidelines. While women recognized the serious health threat that breast cancer poses and that early detection of breast cancer is important, only 30% of women reported feeling well informed about the disease. Many participants

  16. African-Americans and Alzheimer's

    Science.gov (United States)

    ... Share Plus on Google Plus African-Americans and Alzheimer's alz.org | IHaveAlz Introduction 10 Warning Signs Brain ... African-Americans are at a higher risk for Alzheimer's disease. Many Americans dismiss the warning signs of ...

  17. A Qualitative Evaluation of a Faith-Based Breast and Cervical Cancer Screening Intervention for African American Women

    Science.gov (United States)

    Matthews, Alicia K.; Berrios, Nerida; Darnell, Julie S.; Calhoun, Elizabeth

    2006-01-01

    This article presents a formative evaluation of a CDC Racial and Ethnic Approaches to Community Health (REACH) 2010 faith-based breast and cervical cancer early detection and prevention intervention for African American women living in urban communities. Focus groups were conducted with a sample of women (N = 94) recruited from each church…

  18. Adaptation of a Cancer Clinical Trials Education Program for African American and Latina/o Community Members

    Science.gov (United States)

    Pelto, Debra J.; Sadler, Georgia Robins; Njoku, Ogo; Rodriguez, Maria Carina; Villagra, Cristina; Malcarne, Vanessa L.; Riley, Natasha E.; Behar, Alma I.; Jandorf, Lina

    2016-01-01

    The pilot study reported in this article culturally and linguistically adapted an educational intervention to promote cancer clinical trials (CCTs) participation among Latinas/os and African Americans. The single-session slide presentation with embedded videos, originally developed through a campus-community partnership in Southern California, was…

  19. Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

    DEFF Research Database (Denmark)

    Gusev, Alexander; Shi, Huwenbo; Kichaev, Gleb;

    2016-01-01

    Although genome-wide association studies have identified over 100 risk loci that explain ∼33% of familial risk for prostate cancer (PrCa), their functional effects on risk remain largely unknown. Here we use genotype data from 59,089 men of European and African American ancestries combined with c...

  20. Genetic variants in hypothalamic-pituitary-adrenal axis genes and breast cancer risk in Caucasians and African Americans.

    Science.gov (United States)

    Nan, Hongmei; Dorgan, Joanne F; Rebbeck, Timothy R

    2015-01-01

    Elevated circulating levels of the adrenal androgen dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) are associated with increased breast cancer risk in prospective studies. Genetic variants in hypothalamic-pituitary-adrenal (HPA) axis genes may contribute to these circulating hormone levels, and consequently to breast cancer risk. No previous studies have examined the effects of genetic variants in HPA axis genes on breast cancer risk. We evaluated the associations of 49 single nucleotide polymorphisms (SNPs) in five HPA axis genes (NR3C1, NR3C2, CRH, CRHR1, and CRHBP) with the risk of breast cancer in the Women's Insights and Shared Experiences (WISE) Study of Caucasians (346 cases and 442 controls), as well as African Americans (149 cases and 246 controls). Of the 49 SNPs evaluated, one showed a nominal significant association (P for trend < 0.05) with breast cancer risk among Caucasians, and another two among African Americans. The age-adjusted additive odds ratio (OR) (95% confidence interval (95% CI)) of the SNP rs11747190[A] in the CRHBP gene for the risk of breast cancer among Caucasian women was 1.45 (1.09-1.94). The age-adjusted additive ORs (95% CIs) of two SNPs (CRHBP rs1700688[T] and CRHR1 rs17689471[C]) for the risk of breast cancer among African American women were 1.84 (1.13-2.98) and 2.48 (1.20-5.13), respectively. However, these SNPs did not show significant associations after correction for multiple testing. Our findings do not provide strong supportive evidence for the contribution of genetic variants in these HPA axis genes to the risk of developing breast cancer in either Caucasians or African Americans. PMID:26417403

  1. A comparison of 12-gene colon cancer assay gene expression in African American and Caucasian patients with stage II colon cancer

    OpenAIRE

    Govindarajan, Rangaswamy; Posey, James; Chao, Calvin Y.; Lu, Ruixiao; Jadhav, Trafina; Javed, Ahmed Y.; Javed, Awais; Mahmoud, Fade A.; Osarogiagbon, Raymond U.; Manne, Upender

    2016-01-01

    Background African American (AA) colon cancer patients have a worse prognosis than Caucasian (CA) colon cancer patients, however, reasons for this disparity are not well understood. To determine if tumor biology might contribute to differential prognosis, we measured recurrence risk and gene expression using the Oncotype DX® Colon Cancer Assay (12-gene assay) and compared the Recurrence Score results and gene expression profiles between AA patients and CA patients with stage II colon cancer. ...

  2. EphB2 SNPs and sporadic prostate cancer risk in African American men.

    Directory of Open Access Journals (Sweden)

    Christiane M Robbins

    Full Text Available The EphB2 gene has been implicated as a tumor suppressor gene somatically altered in both prostate cancer (PC and colorectal cancer. We have previously shown an association between an EphB2 germline nonsense variant and risk of familial prostate cancer among African American Men (AAM. Here we set out to test the hypothesis that common variation within the EphB2 locus is associated with increased risk of sporadic PC in AAM. We genotyped a set of 341 single nucleotide polymorphisms (SNPs encompassing the EphB2 locus, including known and novel coding and noncoding variants, in 490 AA sporadic PC cases and 567 matched controls. Single marker-based logistical regression analyses revealed seven EphB2 SNPs showing statistically significant association with prostate cancer risk in our population. The most significant association was achieved for a novel synonymous coding SNP, TGen-624, (Odds Ratio (OR  = 0.22; 95% Confidence Interval (CI 0.08-0.66, p = 1×10(-5. Two other SNPs also show significant associations toward a protective effect rs10465543 and rs12090415 (p = 1×10(-4, OR = 0.49 and 0.7, respectively. Two additional SNPs revealed trends towards an increase in risk of prostate cancer, rs4612601 and rs4263970 (p = 0.001, OR = 1.35 and 1.31, respectively. Furthermore, haplotype analysis revealed low levels of linkage disequilibrium within the region, with two blocks being associated with prostate cancer risk among our population. These data suggest that genetic variation at the EphB2 locus may increase risk of sporadic PC among AAM.

  3. Increased Incidence of Loco-Regional Recurrences Among African American Women with Terminal Stage Breast Cancer

    Directory of Open Access Journals (Sweden)

    Gerardo Colón-Otero

    2008-01-01

    Full Text Available A prospective analysis of women with terminal breast cancer admitted to CHNE from November 2006-August 2007 evaluated anecdotal observations that African American (AA women are likelier than Caucasian women to evidence loco-regional recurrences (LRR. Women with terminal breast cancer who were admitted to CHNE, a not-for-profit hospice serving over 90% of Northeast Florida hospice patients, were eligible for participation. 134 terminal breast cancer patients were assessed by hospice nurses for LRR presence via chest wall examination. 80% of them (107 were Caucasian, 17% (23 were AA and 3% (4 were of other ethnicities. Evidence of LRR were noted in 13% of the women (17/134. The pro- portion of patients with LRR was higher in AA women than Caucasian women (26% vs. 10%, 6/23 vs. 11/107, respectively, although this difference was not statistically significant (p = 0.08. The majority of Caucasian women with LRR consented to a medical record review, but a minority of AA women consented (8/11 vs. 2/6, respectively, p = 0.16.Conclusion: Evaluating disparities in breast cancer care outcomes is possible by reviewing data from patients served by hospice programs that aid a majority of patients within a community. This pilot data suggests that AA women with breast cancer have a higher incidence of loco-regional failure as a component of their terminal breast cancer disease than Caucasian women. A smaller proportion of AA patients and families agreed to participate in a medical record review study than Caucasians. Larger studies are necessary to confirm these findings, to elucidate factors contributing to disparities and to develop potential solutions.

  4. Differential endothelial cell gene expression by African Americans versus Caucasian Americans: a possible contribution to health disparity in vascular disease and cancer

    OpenAIRE

    Milbauer LC; Wei P; Enenstein J; Nguyen J; Pan W; Hebbel RP

    2011-01-01

    Abstract Background Health disparities and the high prevalence of cardiovascular disease continue to be perplexing worldwide health challenges. This study addresses the possibility that genetic differences affecting the biology of the vascular endothelium could be a factor contributing to the increased burden of cardiovascular disease and cancer among African Americans (AA) compared to Caucasian Americans (CA). Methods From self-identified, healthy, 20 to 29-year-old AA (n = 21) and CA (n = 1...

  5. Diet, microbiota, and microbial metabolites in colon cancer risk in rural Africans and African Americans

    NARCIS (Netherlands)

    Ou, J.; Carbonero, F.; Zoetendal, E.G.; Delany, J.P.; Wang, M.; Newton, K.; Gaskins, H.R.; O'Keefe, S.F.

    2013-01-01

    BACKGROUND: Epidemiologic studies have suggested that most cases of sporadic colon cancer can be attributed to diet. The recognition that colonic microbiota have a major influence on colonic health suggests that they might mediate colonic carcinogenesis. OBJECTIVE: To examine the hypothesis that the

  6. A genome-wide scan for breast cancer risk haplotypes among African American women.

    Directory of Open Access Journals (Sweden)

    Chi Song

    Full Text Available Genome-wide association studies (GWAS simultaneously investigating hundreds of thousands of single nucleotide polymorphisms (SNP have become a powerful tool in the investigation of new disease susceptibility loci. Haplotypes are sometimes thought to be superior to SNPs and are promising in genetic association analyses. The application of genome-wide haplotype analysis, however, is hindered by the complexity of haplotypes themselves and sophistication in computation. We systematically analyzed the haplotype effects for breast cancer risk among 5,761 African American women (3,016 cases and 2,745 controls using a sliding window approach on the genome-wide scale. Three regions on chromosomes 1, 4 and 18 exhibited moderate haplotype effects. Furthermore, among 21 breast cancer susceptibility loci previously established in European populations, 10p15 and 14q24 are likely to harbor novel haplotype effects. We also proposed a heuristic of determining the significance level and the effective number of independent tests by the permutation analysis on chromosome 22 data. It suggests that the effective number was approximately half of the total (7,794 out of 15,645, thus the half number could serve as a quick reference to evaluating genome-wide significance if a similar sliding window approach of haplotype analysis is adopted in similar populations using similar genotype density.

  7. Obesity, weight gain, and ovarian cancer risk in African American women.

    Science.gov (United States)

    Bandera, Elisa V; Qin, Bo; Moorman, Patricia G; Alberg, Anthony J; Barnholtz-Sloan, Jill S; Bondy, Melissa; Cote, Michele L; Funkhouser, Ellen; Peters, Edward S; Schwartz, Ann G; Terry, Paul; Schildkraut, Joellen M

    2016-08-01

    Although there is growing evidence that higher adiposity increases ovarian cancer risk, little is known about its impact in African American (AA) women, the racial/ethnic group with the highest prevalence of obesity. We evaluated the impact of body mass index (BMI) 1 year before diagnosis and weight gain since age 18 years on ovarian cancer risk in a population-based case-control study in AA women in 11 geographical areas in the US. Cases (n = 492) and age and site matched controls (n = 696) were identified through rapid case ascertainment and random-digit-dialing, respectively. Information was collected on demographic and lifestyle factors, including self-reported height, weight at age 18 and weight 1 year before diagnosis/interview. Multivariable logistic regression was used to compute odds ratios (OR) and 95% confidence intervals (CI), adjusting for potential covariates. Obese women had elevated ovarian cancer risk, particularly for BMI ≥ 40 kg/m(2) compared to BMI <25 (OR = 1.72, 95% CI: 1.12-2.66; p for trend: 0.03). There was also a strong association with weight gain since age 18 (OR: 1.52; 95% CI: 1.07-2.16; p for trend: 0.02) comparing the highest to lowest quartile. In stratified analyses by menopausal status, the association with BMI and weight gain was limited to postmenopausal women, with a 15% (95% CI: 1.05-1.23) increase in risk per 5 kg/m(2) of BMI and 6% (95% CI: 1.01-1.10) increase in risk per 5 kg of weight gain. Excluding hormone therapy users essentially did not change results. Obesity and excessive adult weight gain may increase ovarian cancer risk in post-menopausal AA women. PMID:27038123

  8. Understanding the Breast Cancer Experience of Survivors: a Qualitative Study of African American Women in Rural Eastern North Carolina.

    Science.gov (United States)

    Torres, Essie; Dixon, Crystal; Richman, Alice R

    2016-03-01

    The purpose of this study is to gain an in-depth understanding of African American breast cancer survivors' experiences, barriers and facilitators in accessing breast cancer treatment, and challenges in adherence to follow-up care. We conducted seven focus groups with 32 African American women with breast cancer in three rural counties in eastern North Carolina during August-November 2013. Surveys were also utilized to gather basic demographic and breast health history information. Thematic analysis was performed using the immersion crystallization approach. Several common areas of life affected by breast cancer included faith and support networks, psychosocial well-being, and quality of care issues. Faith in God was an important coping mechanism essential to all women in the study and a critical facilitator in survivorship. Support networks consisted of family, church-family, friends, and co-workers. The concept of fear included the discovery of breast cancer and fear of death, negative side effects of treatment, and social stigma of having breast cancer. Factors that influenced provider-patient relationship were age of provider, perceived lack of empathy, and providers leaving during treatment. Participants also expressed their lack of knowledge regarding a number of the side effects they were experiencing during and after their treatment. Results of this study contribute to the assessment of potential coping mechanisms used by African American breast cancer survivors (i.e., spirituality, positive attitudes, and support networks) that can potentially be effective and have a positive impact on the adjustment of life for survivors. PMID:25877467

  9. Cancer statistics for African Americans, 2016: Progress and opportunities in reducing racial disparities.

    Science.gov (United States)

    DeSantis, Carol E; Siegel, Rebecca L; Sauer, Ann Goding; Miller, Kimberly D; Fedewa, Stacey A; Alcaraz, Kassandra I; Jemal, Ahmedin

    2016-07-01

    In this article, the American Cancer Society provides the estimated number of new cancer cases and deaths for blacks in the United States and the most recent data on cancer incidence, mortality, survival, screening, and risk factors for cancer. Incidence data are from the National Cancer Institute, the Centers for Disease Control and Prevention, and the North American Association of Central Cancer Registries, and mortality data are from the National Center for Health Statistics. Approximately 189,910 new cases of cancer and 69,410 cancer deaths will occur among blacks in 2016. Although blacks continue to have higher cancer death rates than whites, the disparity has narrowed for all cancers combined in men and women and for lung and prostate cancers in men. In contrast, the racial gap in death rates has widened for breast cancer in women and remained level for colorectal cancer in men. The reduction in overall cancer death rates since the early 1990s translates to the avoidance of more than 300,000 deaths among blacks. In men, incidence rates from 2003 to 2012 decreased for all cancers combined (by 2.0% per year) as well as for the top 3 cancer sites (prostate, lung, and colorectal). In women, overall rates during the corresponding time period remained unchanged, reflecting increasing trends in breast cancer combined with decreasing trends in lung and colorectal cancer rates. Five-year relative survival is lower for blacks than whites for most cancers at each stage of diagnosis. The extent to which these disparities reflect unequal access to health care versus other factors remains an active area of research. Progress in reducing cancer death rates could be accelerated by ensuring equitable access to prevention, early detection, and high-quality treatment. CA Cancer J Clin 2016;66:290-308. © 2016 American Cancer Society. PMID:26910411

  10. IGF2R Genetic Variants, Circulating IGF2 Concentrations and Colon Cancer Risk in African Americans and Whites

    OpenAIRE

    Cathrine Hoyo; Susan K Murphy; Schildkraut, Joellen M; Vidal, Adriana C.; David Skaar; Millikan, Robert C.; Joseph Galanko; Sandler, Robert S.; Randy Jirtle; Temitope Keku

    2012-01-01

    The Mannose 6 Phosphate/Insulin-like Growth Factor Receptor-2 (IGF2R) encodes a type-1 membrane protein that modulates availability of the potent mitogen, IGF2. We evaluated the associations between IGF2R non-synonymous genetic variants (c.5002G>A, Gly1619Arg(rs629849), and c.901C>G, Leu252Val(rs8191754)), circulating IGF2 levels, and colon cancer (CC) risk among African American and White participants enrolled in the North Carolina Colon Cancer Study (NCCCS). Generalized linear models were u...

  11. Employing the Church as a Marketer of Cancer Prevention: A Look at a Health Promotion Project Aimed to Reduce Colorectal Cancer Among African Americans in the Midwest

    OpenAIRE

    Lumpkins, Crystal Y.; Coffey, Candice R.; Daley, Christine M; Greiner, K. Allen

    2013-01-01

    Health promotion programs designed to address colorectal cancer disparities among African Americans are increasing. Unfortunately, this group still shoulders a disproportionate mortality burden in the United States; these numbers are also reflective of colorectal cancer (CRC) disparities in the Midwest. The purpose of this study was to extrapolate results from in-depth interviews and brief surveys on the effectiveness of the church as a social marketer of CRC-prevention messages. Results show...

  12. Health Promoting Life-Style Behaviors and Systemic Inflammation in African American and Caucasian Women Prior to Chemotherapy for Breast Cancer

    OpenAIRE

    Debra E. Lyon; Lathika Mohanraj; Debra Lynch Kelly; RK Elswick Jr

    2014-01-01

    Background: Racial disparities in breast cancer outcomes persist, with differential adverse outcomes in African American women. Although research has examined possible genetic differences, there has been little research on potentially modifiable characteristics such as health promoting behaviors. The purpose of this article is to describe the characteristics and to compare the differences by race in lifestyle factors and inflammatory biomarkers in African American and Caucasian women with bre...

  13. Development of a Spiritually Based Educational Intervention to Increase Informed Decision Making for Prostate Cancer Screening Among Church-Attending African American Men

    OpenAIRE

    Holt, Cheryl L.; Wynn, Theresa A.; Southward, Penny; Litaker, Mark S.; Jeames, Sanford; Schulz, Emily

    2009-01-01

    One way of developing culturally relevant health communication in the African American church setting is to develop spiritually based interventions, in which the health message is framed by relevant spiritual themes and scripture. In this article we describe the development of a community health advisor (CHA)-led intervention aimed at increasing informed decision making (IDM) for prostate cancer screening among church-attending African American men. Full-color print educational booklets were ...

  14. African-Americans and Heart Disease, Stroke

    Science.gov (United States)

    ... Pressure High Blood Pressure Tools & Resources Stroke More African-Americans and Heart Disease, Stroke Updated:Apr 18, ... of getting those diseases are even higher for African-Americans. The good news is, African-Americans can ...

  15. Understanding and effectively addressing breast cancer in African American women: Unpacking the social context.

    Science.gov (United States)

    Williams, David R; Mohammed, Selina A; Shields, Alexandra E

    2016-07-15

    Black women have a higher incidence of breast cancer before the age of 40 years, more severe disease at all ages, and an elevated mortality risk in comparison with white women. There is limited understanding of the contribution of social factors to these patterns. Elucidating the role of the social determinants of health in breast cancer disparities requires greater attention to how risk factors for breast cancer unfold over the lifecourse and to the complex ways in which socioeconomic status and racism shape exposure to psychosocial, physical, chemical, and other individual and community-level assaults that increase the risk of breast cancer. Research that takes seriously the social context in which black women live is also needed to maximize the opportunities to prevent breast cancer in this underserved group. Cancer 2016;122:2138-49. © 2016 American Cancer Society. PMID:26930024

  16. Barriers to Obtaining Sera and Tissue Specimens of African-American Women for the Advancement of Cancer Research

    Science.gov (United States)

    Strissel, Katherine J.; Nicholas, Dequina A.; Castagne-Charlotin, Myriam; Ko, Naomi; Denis, Gerald V.

    2016-01-01

    African-American women, a historically understudied and underserved group, have increased risk for triple-negative breast cancer and obesity-associated disease. Obesity-associated metabolic diseases share a common link of low grade chronic inflammation, but not all obese women have metabolic disturbances or are inflamed. One goal of our ongoing research is to identify blood biomarkers that can predict increased risk of breast cancer in women who have obesity or metabolic dysfunction. However, vulnerable populations that stand to benefit most from advances in biomedical research are also underrepresented in research studies. The development of effective, novel approaches for cancer prevention and treatment will require significant basic medical research effort to establish the necessary evidence base in multiple populations. Work with vulnerable human subjects at a safety net hospital enabled us to comment on potential obstacles to obtaining serological and tissue specimens from African-American women. Here, we report some unexpected barriers to participation in our ongoing research study that might inform future efforts. PMID:27441007

  17. Employing the church as a marketer of cancer prevention: a look at a health promotion project aimed to reduce colorectal cancer among African Americans in the Midwest.

    Science.gov (United States)

    Lumpkins, Crystal Y; Coffey, Candice R; Daley, Christine M; Greiner, K Allen

    2013-01-01

    Health promotion programs designed to address colorectal cancer disparities among African Americans are increasing. Unfortunately, this group still shoulders a disproportionate mortality burden in the United States; these numbers are also reflective of colorectal cancer (CRC) disparities in the Midwest. The purpose of this study was to extrapolate results from in-depth interviews and brief surveys on the effectiveness of the church as a social marketer of CRC-prevention messages. Results show that pastors believe the congregation has limited knowledge about CRC risk and prevention; they also believe the church can improve cancer-prevention communication among members and those affiliated with the church. PMID:23718957

  18. Barriers to prostate cancer prevention and community recommended health education strategies in an urban African American community in Jackson, Mississippi.

    Science.gov (United States)

    Ekúndayò, Olúgbémiga T; Tataw, David B

    2013-01-01

    This article describes the use of survey research in collaboration with the African American urban community of Georgetown, Jackson, Mississippi to identify and understand prostate cancer knowledge, resource utilization, and health education strategies considered most effective in reaching the community with prostate cancer prevention messages. The study revealed profound needs in disease identification and resources awareness and utilization. Barriers to utilization were identified by participants to include lack of self-efficacy, low self-esteem, lack of trust in the health care system, limited knowledge of prostate pathology, and limited ability to pay. Participants' recommended strategies for reaching the community with prostate cancer education include traditional and nontraditional strategies. The list of recommendations exclude modern-day outlets such as handheld devices, Twitter, Facebook, blogs, wikis, and other Internet-based outlets. The findings provide a road map for program development and an intervention research agenda custom-tailored to the Georgetown community of Jackson, Mississippi. PMID:23805806

  19. Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

    Science.gov (United States)

    Gusev, Alexander; Shi, Huwenbo; Kichaev, Gleb; Pomerantz, Mark; Li, Fugen; Long, Henry W.; Ingles, Sue A.; Kittles, Rick A.; Strom, Sara S.; Rybicki, Benjamin A.; Nemesure, Barbara; Isaacs, William B.; Zheng, Wei; Pettaway, Curtis A.; Yeboah, Edward D.; Tettey, Yao; Biritwum, Richard B.; Adjei, Andrew A.; Tay, Evelyn; Truelove, Ann; Niwa, Shelley; Chokkalingam, Anand P.; John, Esther M.; Murphy, Adam B.; Signorello, Lisa B.; Carpten, John; Leske, M. Cristina; Wu, Suh-Yuh; Hennis, Anslem J. M.; Neslund-Dudas, Christine; Hsing, Ann W.; Chu, Lisa; Goodman, Phyllis J.; Klein, Eric A.; Witte, John S.; Casey, Graham; Kaggwa, Sam; Cook, Michael B.; Stram, Daniel O.; Blot, William J.; Eeles, Rosalind A.; Easton, Douglas; Kote-Jarai, ZSofia; Al Olama, Ali Amin; Benlloch, Sara; Muir, Kenneth; Giles, Graham G.; Southey, Melissa C.; Fitzgerald, Liesel M.; Gronberg, Henrik; Wiklund, Fredrik; Aly, Markus; Henderson, Brian E.; Schleutker, Johanna; Wahlfors, Tiina; Tammela, Teuvo L. J.; Nordestgaard, Børge G.; Key, Tim J.; Travis, Ruth C.; Neal, David E.; Donovan, Jenny L.; Hamdy, Freddie C.; Pharoah, Paul; Pashayan, Nora; Khaw, Kay-Tee; Stanford, Janet L.; Thibodeau, Stephen N.; McDonnell, Shannon K.; Schaid, Daniel J.; Maier, Christiane; Vogel, Walther; Luedeke, Manuel; Herkommer, Kathleen; Kibel, Adam S.; Cybulski, Cezary; Wokolorczyk, Dominika; Kluzniak, Wojciech; Cannon-Albright, Lisa; Teerlink, Craig; Brenner, Hermann; Dieffenbach, Aida K.; Arndt, Volker; Park, Jong Y.; Sellers, Thomas A.; Lin, Hui-Yi; Slavov, Chavdar; Kaneva, Radka; Mitev, Vanio; Batra, Jyotsna; Spurdle, Amanda; Clements, Judith A.; Teixeira, Manuel R.; Pandha, Hardev; Michael, Agnieszka; Paulo, Paula; Maia, Sofia; Kierzek, Andrzej; Cook, Margaret; Guy, Michelle; Govindasami, Koveela; Leongamornlert, Daniel; Sawyer, Emma J.; Wilkinson, Rosemary; Saunders, Edward J.; Tymrakiewicz, Malgorzata; Dadaev, Tokhir; Morgan, Angela; Fisher, Cyril; Hazel, Steve; Livni, Naomi; Lophatananon, Artitaya; Pedersen, John; Hopper, John L.; Adolfson, Jan; Stattin, Paer; Johansson, Jan-Erik; Cavalli-Bjoerkman, Carin; Karlsson, Ami; Broms, Michael; Auvinen, Anssi; Kujala, Paula; Maeaettaenen, Liisa; Murtola, Teemu; Taari, Kimmo; Weischer, Maren; Nielsen, Sune F.; Klarskov, Peter; Roder, Andreas; Iversen, Peter; Wallinder, Hans; Gustafsson, Sven; Cox, Angela; Brown, Paul; George, Anne; Marsden, Gemma; Lane, Athene; Davis, Michael; Zheng, Wei; Signorello, Lisa B.; Blot, William J.; Tillmans, Lori; Riska, Shaun; Wang, Liang; Rinckleb, Antje; Lubiski, Jan; Stegmaier, Christa; Pow-Sang, Julio; Park, Hyun; Radlein, Selina; Rincon, Maria; Haley, James; Zachariah, Babu; Kachakova, Darina; Popov, Elenko; Mitkova, Atanaska; Vlahova, Aleksandrina; Dikov, Tihomir; Christova, Svetlana; Heathcote, Peter; Wood, Glenn; Malone, Greg; Saunders, Pamela; Eckert, Allison; Yeadon, Trina; Kerr, Kris; Collins, Angus; Turner, Megan; Srinivasan, Srilakshmi; Kedda, Mary-Anne; Alexander, Kimberly; Omara, Tracy; Wu, Huihai; Henrique, Rui; Pinto, Pedro; Santos, Joana; Barros-Silva, Joao; Conti, David V.; Albanes, Demetrius; Berg, Christine; Berndt, Sonja I.; Campa, Daniele; Crawford, E. David; Diver, W. Ryan; Gapstur, Susan M.; Gaziano, J. Michael; Giovannucci, Edward; Hoover, Robert; Hunter, David J.; Johansson, Mattias; Kraft, Peter; Le Marchand, Loic; Lindström, Sara; Navarro, Carmen; Overvad, Kim; Riboli, Elio; Siddiq, Afshan; Stevens, Victoria L.; Trichopoulos, Dimitrios; Vineis, Paolo; Yeager, Meredith; Trynka, Gosia; Raychaudhuri, Soumya; Schumacher, Frederick R.; Price, Alkes L.; Freedman, Matthew L.; Haiman, Christopher A.; Pasaniuc, Bogdan

    2016-01-01

    Although genome-wide association studies have identified over 100 risk loci that explain ∼33% of familial risk for prostate cancer (PrCa), their functional effects on risk remain largely unknown. Here we use genotype data from 59,089 men of European and African American ancestries combined with cell-type-specific epigenetic data to build a genomic atlas of single-nucleotide polymorphism (SNP) heritability in PrCa. We find significant differences in heritability between variants in prostate-relevant epigenetic marks defined in normal versus tumour tissue as well as between tissue and cell lines. The majority of SNP heritability lies in regions marked by H3k27 acetylation in prostate adenoc7arcinoma cell line (LNCaP) or by DNaseI hypersensitive sites in cancer cell lines. We find a high degree of similarity between European and African American ancestries suggesting a similar genetic architecture from common variation underlying PrCa risk. Our findings showcase the power of integrating functional annotation with genetic data to understand the genetic basis of PrCa. PMID:27052111

  20. A tailored prostate cancer education intervention for low-income African Americans: impact on knowledge and screening.

    Science.gov (United States)

    Ukoli, Flora A; Patel, Kushal; Hargreaves, Margaret; Beard, Katina; Moton, Pierre J; Bragg, Richard; Beech, Derrick; Davis, Rodney

    2013-02-01

    African American men bear disproportionate burden of prostate cancer (PCa) that can be reduced by early detection. A 15-minute culturally appropriate PCa education intervention developed to communicate effective, relevant, and balanced PCa screening information to low-income African American men was evaluated in men 42 years and older who had not been screened in one year. Of 539 men enrolled, 392 (72.7%) completed the six-month follow-up. Mean age was 54.4±8.9, 34.7% had no high school diploma, and 65.3% earned less than $25,000 annually. Barriers to screening included health insurance (41.4%), discomfort of digital rectal exam (32.1%), and fear of cancer diagnosis (29.9%). Mean knowledge score of 21 points increased from 13.27±3.51 to 14.95±4.14 (pschool diploma recorded the lowest post-intervention PCa knowledge and screening rate (47.7%), suggestive of the need for more than a single education session. Annual physicals with free prostate examination can maintain the positive trend observed. PMID:23377736

  1. Cultural Considerations When Caring for African Americans

    Science.gov (United States)

    The EPEC-O (Education in Palliative and End-of-Life Care for Oncology) Self-Study: Cultural Considerations When Caring for African Americans is a free comprehensive multimedia curricula for health professionals caring for persons with cancer and their families.

  2. Association between Plasma 25-Hydroxyvitamin D, Ancestry and Aggressive Prostate Cancer among African Americans and European Americans in PCaP.

    Directory of Open Access Journals (Sweden)

    Susan E Steck

    Full Text Available African Americans (AAs have lower circulating 25-hydroxyvitamin D3 [25(OHD3] concentrations and higher prostate cancer (CaP aggressiveness than other racial/ethnic groups. The purpose of the current study was to examine the relationship between plasma 25(OHD3, African ancestry and CaP aggressiveness among AAs and European Americans (EAs.Plasma 25(OHD3 was measured using LC-MS/MS (Liquid Chromatography Tandem Mass Spectrometry in 537 AA and 663 EA newly-diagnosed CaP patients from the North Carolina-Louisiana Prostate Cancer Project (PCaP classified as having either 'high' or 'low' aggressive disease based on clinical stage, Gleason grade and prostate specific antigen at diagnosis. Mean plasma 25(OHD3 concentrations were compared by proportion of African ancestry. Logistic regression was used to calculate multivariable adjusted odds ratios (OR and 95% confidence intervals (95%CI for high aggressive CaP by tertile of plasma 25(OHD3.AAs with highest percent African ancestry (>95% had the lowest mean plasma 25(OHD3 concentrations. Overall, plasma 25(OHD3 was associated positively with aggressiveness among AA men, an association that was modified by calcium intake (ORT 3vs.T1: 2.23, 95%CI: 1.26-3.95 among men with low calcium intake, and ORT 3vs.T1: 0.19, 95%CI: 0.05-0.70 among men with high calcium intake. Among EAs, the point estimates of the ORs were <1.0 for the upper tertiles with CIs that included the null.Among AAs, plasma 25(OHD3 was associated positively with CaP aggressiveness among men with low calcium intake and inversely among men with high calcium intake. The clinical significance of circulating concentrations of 25(OHD3 and interactions with calcium intake in the AA population warrants further study.

  3. Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium.

    Directory of Open Access Journals (Sweden)

    Bogdan Pasaniuc

    2011-04-01

    Full Text Available While genome-wide association studies (GWAS have primarily examined populations of European ancestry, more recent studies often involve additional populations, including admixed populations such as African Americans and Latinos. In admixed populations, linkage disequilibrium (LD exists both at a fine scale in ancestral populations and at a coarse scale (admixture-LD due to chromosomal segments of distinct ancestry. Disease association statistics in admixed populations have previously considered SNP association (LD mapping or admixture association (mapping by admixture-LD, but not both. Here, we introduce a new statistical framework for combining SNP and admixture association in case-control studies, as well as methods for local ancestry-aware imputation. We illustrate the gain in statistical power achieved by these methods by analyzing data of 6,209 unrelated African Americans from the CARe project genotyped on the Affymetrix 6.0 chip, in conjunction with both simulated and real phenotypes, as well as by analyzing the FGFR2 locus using breast cancer GWAS data from 5,761 African-American women. We show that, at typed SNPs, our method yields an 8% increase in statistical power for finding disease risk loci compared to the power achieved by standard methods in case-control studies. At imputed SNPs, we observe an 11% increase in statistical power for mapping disease loci when our local ancestry-aware imputation framework and the new scoring statistic are jointly employed. Finally, we show that our method increases statistical power in regions harboring the causal SNP in the case when the causal SNP is untyped and cannot be imputed. Our methods and our publicly available software are broadly applicable to GWAS in admixed populations.

  4. Intake of energy-dense foods, fast foods, sugary drinks, and breast cancer risk in African American and European American women.

    Science.gov (United States)

    Chandran, Urmila; McCann, Susan E; Zirpoli, Gary; Gong, Zhihong; Lin, Yong; Hong, Chi-Chen; Ciupak, Gregory; Pawlish, Karen; Ambrosone, Christine B; Bandera, Elisa V

    2014-01-01

    Limiting energy-dense foods, fast foods, and sugary drinks that promote weight gain is a cancer prevention recommendation, but no studies have evaluated intake in relation to breast cancer risk in African American (AA) women. In a case-control study with 1692 AA women (803 cases and 889 controls) and 1456 European American (EA) women (755 cases and 701 controls), odds ratios (OR) and 95% confidence intervals (CI) for risk were computed, stratifying for menopausal and estrogen receptor (ER) status. Among postmenopausal EA women, breast cancer risk was associated with frequent consumption of energy-dense foods (OR = 2.95; 95% CI: 1.66-5.22), fast foods (OR = 2.35; 95% CI: 1.38-4.00), and sugary drinks (OR = 2.05; 95% CI: 1.13-3.70). Elevated risk of ER+ tumors in EA women was associated with energy-dense (OR = 1.75; 95% CI: 1.14-2.69) and fast foods (OR = 1.84; 95% CI: 1.22-2.77). Among AA women, frequent fast food consumption was related to premenopausal breast cancer risk (OR = 1.97; 95% CI: 1.13-3.43), and with ER+ tumors. Energy adjustment attenuated risk estimates in AA women, while strengthening them among EA women. Frequent consumption of energy-dense and fast foods that have poor nutritive value appeared to increase breast cancer risk in AA and EA women, with differences by menopausal status and ER status. PMID:25265504

  5. BMI1, stem cell factor acting as novel serum-biomarker for Caucasian and African-American prostate cancer.

    Directory of Open Access Journals (Sweden)

    Hifzur Rahman Siddique

    Full Text Available BACKGROUND: Lack of reliable predictive biomarkers is a stumbling block in the management of prostate cancer (CaP. Prostate-specific antigen (PSA widely used in clinics has several caveats as a CaP biomarker. African-American CaP patients have poor prognosis than Caucasians, and notably the serum-PSA does not perform well in this group. Further, some men with low serum-PSA remain unnoticed for CaP until they develop disease. Thus, there is a need to identify a reliable diagnostic and predictive biomarker of CaP. Here, we show that BMI1 stem-cell protein is secretory and could be explored for biomarker use in CaP patients. METHODOLOGY/PRINCIPAL FINDINGS: Semi-quantitative analysis of BMI1 was performed in prostatic tissues of TRAMP (autochthonous transgenic mouse model, human CaP patients, and in cell-based models representing normal and different CaP phenotypes in African-American and Caucasian men, by employing immunohistochemistry, immunoblotting and Slot-blotting. Quantitative analysis of BMI1 and PSA were performed in blood and culture-media of siRNA-transfected and non-transfected cells by employing ELISA. BMI1 protein is (i secreted by CaP cells, (ii increased in the apical region of epithelial cells and stromal region in prostatic tumors, and (iii detected in human blood. BMI1 is detectable in blood of CaP patients in an order of increasing tumor stage, exhibit a positive correlation with serum-PSA and importantly is detectable in patients which exhibit low serum-PSA. The clinical significance of BMI1 as a biomarker could be ascertained from observation that CaP cells secrete this protein in higher levels than cells representative of benign prostatic hyperplasia (BPH. CONCLUSIONS/SIGNIFICANCE: BMI1 could be developed as a dual bio-marker (serum and biopsy for the diagnosis and prognosis of CaP in Caucasian and African-American men. Though compelling these data warrant further investigation in a cohort of African-American patients.

  6. IGF2R Genetic Variants, Circulating IGF2 Concentrations and Colon Cancer Risk in African Americans and Whites

    Directory of Open Access Journals (Sweden)

    Cathrine Hoyo

    2012-01-01

    Full Text Available The Mannose 6 Phosphate/Insulin-like Growth Factor Receptor-2 (IGF2R encodes a type-1 membrane protein that modulates availability of the potent mitogen, IGF2. We evaluated the associations between IGF2R non-synonymous genetic variants (c.5002G>A, Gly1619Arg(rs629849, and c.901C>G, Leu252Val(rs8191754, circulating IGF2 levels, and colon cancer (CC risk among African American and White participants enrolled in the North Carolina Colon Cancer Study (NCCCS. Generalized linear models were used to compare circulating levels of IGF2 among 298 African American and 518 White controls. Logistic regression models were used to estimate odds ratios (ORs and 95% confidence intervals (CIs for the association of IGF2R genetic variants and CC risk. Women homozygous for the IGF2R c.5002 G>A allele, had higher mean levels of circulating IGF2, 828 (SD=321 ng/ml compared to non-carriers, 595 (SD=217 ng/ml (p-value=0.01. This pattern was not apparent in individuals homozygous for the IGF2R c.901 C>G variant. Whites homozygous for the IGF2R c.901 C>G variant trended towards a higher risk of CC, OR=2.2 [95% CI(0.9–5.4], whereas carrying the IGF2R c.5002 G>A variant was not associated with CC risk. Our findings support the hypothesis that being homozygous for the IGF2R c.5002 G>A modulates IGF2 circulating levels in a sex-specific manner, and while carrying the IGF2R c.901 C>G may increase cancer risk, the mechanism may not involve modulation of circulating IGF2.

  7. Vitamin D and African Americans

    Science.gov (United States)

    Vitamin D insufficiency is more prevalent among African Americans than other Americans and, in North America, most young, healthy blacks do not achieve optimal 25-hydroxyvitamin D [25(OH)D] concentrations at any time of the year. This is primarily due to the fact that pigmentation reduces vitamin D...

  8. Virtual Weight Loss Program in Maintaining Weight in African American Breast Cancer Survivors

    Science.gov (United States)

    2016-03-01

    Cancer Survivor; Invasive Breast Carcinoma; Stage IA Breast Cancer; Stage IB Breast Cancer; Stage IIA Breast Cancer; Stage IIB Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer

  9. Health Promoting Life-Style Behaviors and Systemic Inflammation in African American and Caucasian Women Prior to Chemotherapy for Breast Cancer

    Directory of Open Access Journals (Sweden)

    Debra E Lyon

    2014-07-01

    Full Text Available Background: Racial disparities in breast cancer outcomes persist, with differential adverse outcomes in African American women. Although research has examined possible genetic differences, there has been little research on potentially modifiable characteristics such as health promoting behaviors. The purpose of this article is to describe the characteristics and to compare the differences by race in lifestyle factors and inflammatory biomarkers in African American and Caucasian women with breast cancer. Methods: This is a baseline descriptive analysis from an ongoing randomized controlled trial that includes 124 women diagnosed with early stage breast cancer prior to chemotherapy. Data sources included medical records, self-report questionnaires and a blood sample for measures of inflammation. The statistical analysis included descriptive statistics and ANOVA models to determine differences between the two groups. Results: Overall, both groups had low levels of health promoting behaviors. African Americans had a significantly higher body mass index. Caucasian women consumed more alcohol. Levels of C-reactive protein and MIP-1β were significantly higher in African Americans. Conclusion: Potentially modifiable factors such as nutrition, physical activity and levels of inflammation warrant further attention.

  10. FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women

    OpenAIRE

    Barnholtz-Sloan, Jill S; Shetty, Priya B; Guan, Xiaowei; Nyante, Sarah J; Luo, Jingchun; Brennan, Donal J.; Millikan, Robert C.

    2010-01-01

    Twenty-nine single-nucleotide polymorphisms (SNPs) from previously published genome-wide association studies (GWAS) and multiple ancestry informative markers were genotyped in the Carolina Breast Cancer Study (CBCS) (742 African-American (AA) cases, 1230 White cases; 658 AA controls, 1118 White controls). In the entire study population, 9/10 SNPs in fibroblast growth factor receptor 2 (FGFR2) were significantly associated with breast cancer after adjusting for age, race and European ancestry ...

  11. Evaluating genome-wide association study-identified breast cancer risk variants in African-American women.

    Directory of Open Access Journals (Sweden)

    Jirong Long

    Full Text Available Genome-wide association studies (GWAS, conducted mostly in European or Asian descendants, have identified approximately 67 genetic susceptibility loci for breast cancer. Given the large differences in genetic architecture between the African-ancestry genome and genomes of Asians and Europeans, it is important to investigate these loci in African-ancestry populations. We evaluated index SNPs in all 67 breast cancer susceptibility loci identified to date in our study including up to 3,300 African-American women (1,231 cases and 2,069 controls, recruited in the Southern Community Cohort Study (SCCS and the Nashville Breast Health Study (NBHS. Seven SNPs were statistically significant (P ≤ 0.05 with the risk of overall breast cancer in the same direction as previously reported: rs10069690 (5p15/TERT, rs999737 (14q24/RAD51L1, rs13387042 (2q35/TNP1, rs1219648 (10q26/FGFR2, rs8170 (19p13/BABAM1, rs17817449 (16q12/FTO, and rs13329835 (16q23/DYL2. A marginally significant association (P<0.10 was found for three additional SNPs: rs1045485 (2q33/CASP8, rs4849887 (2q14/INHBB, and rs4808801 (19p13/ELL. Three additional SNPs, including rs1011970 (9p21/CDKN2A/2B, rs941764 (14q32/CCDC88C, and rs17529111 (6q14/FAM46A, showed a significant association in analyses conducted by breast cancer subtype. The risk of breast cancer was elevated with an increasing number of risk variants, as measured by quintile of the genetic risk score, from 1.00 (reference, to 1.75 (1.30-2.37, 1.56 (1.15-2.11, 2.02 (1.50-2.74 and 2.63 (1.96-3.52, respectively, (P = 7.8 × 10(-10. Results from this study highlight the need for large genetic studies in AAs to identify risk variants impacting this population.

  12. Genetic variants in anti-Mullerian hormone and anti-Mullerian hormone receptor genes and breast cancer risk in Caucasians and African Americans.

    Science.gov (United States)

    Nan, Hongmei; Dorgan, Joanne F; Rebbeck, Timothy R

    2014-01-01

    Anti-Mullerian hormone (AMH) regulates ovarian folliculogenesis by signaling via its receptors, and elevated serum AMH levels are associated with an increased risk of breast cancer. No previous studies have examined the effects of genetic variants in AMH-related genes on breast cancer risk. We evaluated the associations of 62 single nucleotide polymorphisms (SNPs) in AMH and its receptor genes, including AMH type 1 receptor (ACVR1) and AMH type 2 receptor (AMHR2), with the risk of breast cancer in the Women's Insights and Shared Experiences (WISE) Study of Caucasians (346 cases and 442 controls), as well as African Americans (149 cases and 246 controls). Of the 62 SNPs evaluated, two showed a nominal significant association (P for trend < 0.05) with breast cancer risk among Caucasians, and another two among African Americans. The age-adjusted additive odds ratios (ORs) (95% confidence interval (95% CI)) of those two SNPs (ACVR1 rs12694937[C] and ACVR1 rs2883605[T]) for the risk of breast cancer among Caucasian women were 2.33 (1.20-4.52) and 0.68 (0.47-0.98), respectively. The age-adjusted additive ORs (95% CI) of those two SNPs (ACVR1 rs1146031[G] and AMHR2 functional SNP rs2002555[G]) for the risk of breast cancer among African American women were 0.63 (0.44-0.92) and 1.67 (1.10-2.53), respectively. However, these SNPs did not show significant associations after correction for multiple testing. Our findings do not provide strong supportive evidence for the contribution of genetic variants in AMH-related genes to the risk of developing breast cancer in either Caucasians or African Americans. PMID:25379134

  13. Translating Culture: Contemporary African American Poetry

    OpenAIRE

    Kristina Kočan Šalamon

    2015-01-01

    The paper interrogates cultural specifics of contemporary African American poetry and exhibits translation problems when translating this poetic work. African American writers have always included much of their cultural heritage in their writing and this is immediately noticed by a translator. The cultural elements, such as African American cuisine, attire and style in general, as well as spiritual and religious practices, often play a significant role for African American poets who are procl...

  14. Manganese superoxide dismutase Ala-9Val polymorphism and risk of breast cancer in a population-based case–control study of African Americans and whites

    International Nuclear Information System (INIS)

    A polymorphism in the manganese superoxide dismutase (MnSOD) gene, Ala-9Val, has been examined in association with breast cancer risk in several epidemiologic studies. Results suggest that the Ala allele increases the risk of breast cancer and modifies the effects of environmental exposures that produce oxidative damage to DNA. We examined the role of the MnSOD Ala-9Val polymorphism in a population-based case–control study of invasive and in situ breast cancer in North Carolina. Genotypes were evaluated for 2025 cases (760 African Americans and 1265 whites) and for 1812 controls (677 African Americans and 1135 whites). The odds ratio for MnSOD Ala/Ala versus any MnSOD Val genotypes was not elevated in African Americans (odds ratio = 0.9, 95% confidence interval = 0.7–1.2) or in whites (odds ratio = 1.0, 95% confidence interval = 0.8–1.2). Greater than additive joint effects were observed for the Ala/Ala genotype and smoking, radiation to the chest, and occupational exposure to ionizing radiation. Antagonism was observed between the Ala/Ala genotype and the use of nonsteroidal anti-inflammatory drugs. The MnSOD genotype may contribute to an increased risk of breast cancer in the presence of specific environmental exposures. These results provide further evidence for the importance of reactive oxygen species and of oxidative DNA damage in the etiology of breast cancer

  15. Association between Plasma 25-Hydroxyvitamin D, Ancestry and Aggressive Prostate Cancer among African Americans and European Americans in PCaP

    Science.gov (United States)

    Steck, Susan E.; Arab, Lenore; Zhang, Hongmei; Bensen, Jeannette T.; Fontham, Elizabeth T. H.; Johnson, Candace S.; Mohler, James L.; Smith, Gary J.; Su, Joseph L.; Trump, Donald L.; Woloszynska-Read, Anna

    2015-01-01

    Background African Americans (AAs) have lower circulating 25-hydroxyvitamin D3 [25(OH)D3] concentrations and higher prostate cancer (CaP) aggressiveness than other racial/ethnic groups. The purpose of the current study was to examine the relationship between plasma 25(OH)D3, African ancestry and CaP aggressiveness among AAs and European Americans (EAs). Methods Plasma 25(OH)D3 was measured using LC-MS/MS (Liquid Chromatography Tandem Mass Spectrometry) in 537 AA and 663 EA newly-diagnosed CaP patients from the North Carolina-Louisiana Prostate Cancer Project (PCaP) classified as having either ‘high’ or ‘low’ aggressive disease based on clinical stage, Gleason grade and prostate specific antigen at diagnosis. Mean plasma 25(OH)D3 concentrations were compared by proportion of African ancestry. Logistic regression was used to calculate multivariable adjusted odds ratios (OR) and 95% confidence intervals (95%CI) for high aggressive CaP by tertile of plasma 25(OH)D3. Results AAs with highest percent African ancestry (>95%) had the lowest mean plasma 25(OH)D3 concentrations. Overall, plasma 25(OH)D3 was associated positively with aggressiveness among AA men, an association that was modified by calcium intake (ORT3vs.T1: 2.23, 95%CI: 1.26–3.95 among men with low calcium intake, and ORT3vs.T1: 0.19, 95%CI: 0.05–0.70 among men with high calcium intake). Among EAs, the point estimates of the ORs were <1.0 for the upper tertiles with CIs that included the null. Conclusions Among AAs, plasma 25(OH)D3 was associated positively with CaP aggressiveness among men with low calcium intake and inversely among men with high calcium intake. The clinical significance of circulating concentrations of 25(OH)D3 and interactions with calcium intake in the AA population warrants further study. PMID:25919866

  16. Relationship between tumor DNA methylation status and patient characteristics in African-American and European-American women with breast cancer.

    Directory of Open Access Journals (Sweden)

    Songping Wang

    Full Text Available Aberrant DNA methylation is critical for development and progression of breast cancer. We investigated the association of CpG island methylation in candidate genes and clinicopathological features in 65 African-American (AA and European-American (EA breast cancer patients. Quantitative methylation analysis was carried out on bisulfite modified genomic DNA and sequencing (pyrosequencing for promoter CpG islands of p16, ESR1, RASSF1A, RARβ2, CDH13, HIN1, SFRP1 genes and the LINE1 repetitive element using matched paired non-cancerous and breast tumor specimen (32 AA and 33 EA women. Five of the genes, all known tumor suppressor genes (RASSF1A, RARβ2, CDH13, HIN1 and SFRP1, were found to be frequently hypermethylated in breast tumor tissues but not in the adjacent non-cancerous tissues. Significant differences in the CDH13 methylation status were observed by comparing DNA methylation between AA and EA patients, with more obvious CDH13 methylation differences between the two patient groups in the ER- disease and among young patients (age<50. In addition, we observed associations between CDH13, SFRP1, and RASSF1A methylation and breast cancer subtypes and between SFRP1 methylation and patient's age. Furthermore, tumors that received neoadjuvant therapy tended to have reduced RASSF1A methylation when compared with chemotherapy naïve tumors. Finally, Kaplan Meier survival analysis showed a significant association between methylation at 3 loci (RASSF1A, RARβ2 and CDH13 and reduced overall disease survival. In conclusion, the DNA methylation status of breast tumors was found to be significantly associated with clinicopathological features and race/ethnicity of the patients.

  17. Adaptation of a Cancer Clinical Trials Education Program for African American and Latina/o Community Members.

    Science.gov (United States)

    Pelto, Debra J; Sadler, Georgia Robins; Njoku, Ogo; Rodriguez, Maria Carina; Villagra, Cristina; Malcarne, Vanessa L; Riley, Natasha E; Behar, Alma I; Jandorf, Lina

    2016-08-01

    The pilot study reported in this article culturally and linguistically adapted an educational intervention to promote cancer clinical trials (CCTs) participation among Latinas/os and African Americans. The single-session slide presentation with embedded videos, originally developed through a campus-community partnership in Southern California, was chosen for adaptation because it was perceived to fit the CORRECT model of innovation (credible, observable, relevant, relatively advantageous, easy to understand, compatible, and testable) and because of the potential to customize any components not identified as core, allowing them to be revised for cultural and linguistic alignment in New York City. Most of the 143 community participants (76.2%) were female; most (54.6%) were older than 59 years. More than half (78.3%) preferred to speak English or were bilingual in English and Spanish. A large proportion (41.3%) had not completed high school. Knowledge and perceived benefits and barriers regarding CCT showed small, though statistically significant, increases. There were no statistically significant group differences for changes in mean knowledge, perceived benefits, or perceived barriers when examined by ethnicity, education level, language, or other included sociodemographic variables. However, a small, but statistically significant difference in perceived barriers was observed when examined by country of origin, with the foreign born score worsening 0.08 points (SD = 0.47, p = .007) on the 5-point Likert-type scale administered posteducation compared to preeducation. Participants' open-ended comments demonstrated the acceptability of the topic and intervention. This adaptation resulted in an intervention with the potential to educate African American and Latina/o general community members in a new geographic region about the purpose, methods, and benefits of CCTs. PMID:26493870

  18. Engaging African Americans in Smoking Cessation Programs

    Science.gov (United States)

    Wallen, Jacqueline; Randolph, Suzanne; Carter-Pokras, Olivia; Feldman, Robert; Kanamori-Nishimura, Mariano

    2014-01-01

    Background: African Americans are disproportionately exposed to and targeted by prosmoking advertisements, particularly menthol cigarette ads. Though African Americans begin smoking later than whites, they are less likely to quit smoking than whites. Purpose: This study was designed to explore African American smoking cessation attitudes,…

  19. Wellness among African American Counselors

    Science.gov (United States)

    Day-Vines, Norma L.; Holcomb-McCoy, Cheryl

    2007-01-01

    Although there are various definitions of wellness, few conceptual definitions have addressed the contextual dimensions of wellness relative to African American counselors. The authors present an overview of generic models of wellness, discuss factors that both inhibit and promote wellness, offer some culture-specific models of wellness, and…

  20. Perceptions of African American and European American Teachers on the Education of African American Boys

    Science.gov (United States)

    Bacon, Ellen; Banks, Joy; Young, Kathryn; Jackson, Francesina R.

    2007-01-01

    The authors interviewed 27 teachers (16 African American and 11 European American) on instructional factors contributing to overidentification of behavior problems in African American boys. Interviews focused on teachers' perspectives of effective teachers, teacher-student relationships, and communication styles. Analysis of the interviews showed…

  1. Mortality from Western cancers rose dramatically among African-Americans during the 20th century: are dietary animal products to blame?

    Science.gov (United States)

    McCarty, M F

    2001-08-01

    Statistics compiled by the National Cancer Institute indicate that, between 1935 and 1974, age-adjusted mortality from most 'Western' cancers (those of the breast, colon, prostate, pancreas, ovary, and kidney) rose dramatically in African-Americans. This phenomenon is paralleled by marked increases in the incidence of these cancers in Asia and Southern Europe during the latter 20th century, in conjunction with increased intakes of dietary animal products. A credible case can be made that diets rich in animal products work in various complementary ways to up-regulate serum levels of insulin, free IGF-I, and free sex hormones: hormones that appear to have important promotional activity for Western cancers. It seems likely that dietary animal product intake by black Americans increased substantially during the 20th century, and that this fact is primarily responsible for their concurrent marked increase in mortality from Western cancers. A whole-food vegan diet rich in fruits and vegetables, especially if coupled with regular exercise and smoking avoidance, could be expected to have a remarkably positive impact on African-American cancer risk, reversing the increases in cancer risk incurred during the 20th century. PMID:11461167

  2. Outcome disparities in African American women with triple negative breast cancer: a comparison of epidemiological and molecular factors between African American and Caucasian women with triple negative breast cancer

    International Nuclear Information System (INIS)

    Although diagnosed less often, breast cancer in African American women (AAW) displays different characteristics compared to breast cancer in Caucasian women (CW), including earlier onset, less favorable clinical outcome, and an aggressive tumor phenotype. These disparities may be attributed to differences in socioeconomic factors such as access to health care, lifestyle, including increased frequency of obesity in AAW, and tumor biology, especially the higher frequency of triple negative breast cancer (TNBC) in young AAW. Improved understanding of the etiology and molecular characteristics of TNBC in AAW is critical to determining whether and how TNBC contributes to survival disparities in AAW. Demographic, pathological and survival data from AAW (n = 62) and CW (n = 98) with TNBC were analyzed using chi-square analysis, Student’s t-tests, and log-rank tests. Frozen tumor specimens were available from 57 of the TNBC patients (n = 23 AAW; n = 34 CW); RNA was isolated after laser microdissection of tumor cells and was hybridized to HG U133A 2.0 microarrays. Data were analyzed using ANOVA with FDR <0.05, >2-fold difference defining significance. The frequency of TNBC compared to all BC was significantly higher in AAW (28%) compared to CW (12%), however, significant survival and pathological differences were not detected between populations. Gene expression analysis revealed the tumors were more similar than different at the molecular level, with only CRYBB2P1, a pseudogene, differentially expressed between populations. Among demographic characteristics, AAW consumed significantly lower amounts of caffeine and alcohol, were less likely to breastfeed and more likely to be obese. These data suggest that TNBC in AAW is not a unique disease compared to TNBC in CW. Rather, higher frequency of TNBC in AAW may, in part, be attributable to the effects of lifestyle choices. Because these risk factors are modifiable, they provide new opportunities for the development of risk

  3. An examination of racial differences in 5-year survival of cervical cancer among African American and white American women in the southeastern US from 1985 to 2010.

    Science.gov (United States)

    Weragoda, Janaka; Azuero, Andres; Badiga, Suguna; Bell, Walter C; Matthews, Roland; Piyathilake, Chandrika

    2016-08-01

    Disparities in Cervical Cancer (CC) mortality outcomes between African American (AA) and White women have been studied for decades. However, conclusions about the effect of race on CC survival differ across studies. This study assessed differences in CC survival between AA and White women diagnosed between 1985 and 2010 and treated at two major hospitals in the southeastern US. The study sample included 925 AA and 1192 White women diagnosed with cervical adenocarcinoma, adenosquamous cell carcinoma, or squamous cell carcinoma. Propensity score adjustment and matching were employed to compare 5-year survival between the two racial groups. Crude comparisons suggested relevant racial differences in survival. However, the racial differences became of small magnitude after propensity-score adjustment and in matched analyses. Nonlinear models identified age at diagnosis, cancer stage, mode of treatment, and histological subtype as the most salient characteristics predicting 5-year survival of CC, yet these characteristics were also associated with race. Crude racial differences in survival might be partly explained by underlying differences in the characteristics of racial groups, such as age at diagnosis, histological subtype, cancer stage, and the mode of treatment. The study results highlight the need to improve access to early screening and treatment opportunities for AA women to improve posttreatment survival from CC. PMID:27185053

  4. Identifying Barriers to Colonoscopy Screening for Nonadherent African American Participants in a Patient Navigation Intervention

    Science.gov (United States)

    Sly, Jamilia R.; Edwards, Tiffany; Shelton, Rachel C.; Jandorf, Lina

    2013-01-01

    African Americans have a higher rate of colorectal cancer (CRC) mortality than other racial/ethnic groups. This disparity is alarming given that CRC is largely preventable through the use of endoscopy (screening colonoscopy or sigmoidoscopy), yet rates of CRC screening among African Americans is suboptimal. Only 48.9% of African Americans are…

  5. A Comparison Between Caucasians and African Americans in Willingness to Participate in Cancer Clinical Trials: The Roles of Knowledge, Distrust, Information Sources, and Religiosity.

    Science.gov (United States)

    Meng, Jingbo; McLaughlin, Margaret; Pariera, Katrina; Murphy, Sheila

    2016-06-01

    This study aims to (a) examine the roles of knowledge, distrust in medical professionals, information sources, and 2 dimensions of religiosity (i.e., religious activity and religious belief) in influencing willingness to participate (WTP) in cancer clinical trials and to (b) compare the results for Caucasians and African Americans in order to inform future recruitment. An online survey was fielded via a Knowledge Networks panel with a nationally representative sample including 478 Caucasians and 173 African Americans. The results showed that distrust in medical professionals was a strong barrier to WTP for both ethnic groups, whereas factual knowledge about trial procedures was not associated with WTP for either ethnic group. Seeking trial information from doctors was positively associated with WTP for Caucasians; seeking trial information from hospitals was positively associated with WTP for African Americans. More interestingly, levels of religious activity negatively predicted WTP for Caucasians but positively predicted WTP for African Americans. Self-reported religious belief was not associated with WTP for either ethnic group. In sum, although distrust is a common barrier to WTP, the influence of preferred information sources and religious activity on WTP varies as a function of ethnicity. PMID:27175604

  6. Development of a spiritually based educational intervention to increase informed decision making for prostate cancer screening among church-attending African American men.

    Science.gov (United States)

    Holt, Cheryl L; Wynn, Theresa A; Southward, Penny; Litaker, Mark S; Jeames, Sanford; Schulz, Emily

    2009-09-01

    One way of developing culturally relevant health communication in the African American church setting is to develop spiritually based interventions, in which the health message is framed by relevant spiritual themes and scripture. In this article we describe the development of a community health advisor(CHA)-led intervention aimed at increasing informed decision making (IDM) for prostate cancer screening among church-attending African American men. Full-color print educational booklets were developed and pilot tested with extensive community participation of church-attending African American men age-eligible for screening. The intervention development phase consisted of ideas solicited from an advisory panel of African American men (N = 10), who identified core content and developed the spiritual themes. In the intervention pilot testing phase, prototypes of the intervention materials were pilot tested for graphic appeal in two focus groups (N = 16), and content was tested for acceptability and comprehension using individual cognitive response interviews (N = 10). Recommendations were made for project branding and logo and for use of graphics of real people in the educational materials. Significant feedback was obtained from the focus groups, on the graphics, colors, fonts, continuity, titles, and booklet size/shape. The importance of working closely with the community when developing interventions is discussed, as well as the importance of pilot testing of educational materials. PMID:19731129

  7. The Southeastern u.S. collaborative center of Excellence in the Elimination of disparities (SUCCEED): reducing Breast and cervical cancer disparities for african american Women

    OpenAIRE

    Reese, Le’Roy E.; Blumenthal, Daniel S; Haynes, Venice E.

    2012-01-01

    This supplement highlights the efforts of Morehouse School of Medicine’s Prevention Research Center and its partners to reduce the disparities experienced by African American women for breast and cervical cancer in Georgia, North Carolina and South Carolina. The project (entitled the Southeastern U.S. Collaborative CEED, or SUCCEED) is supported by a Centers for Disease Control and Prevention (CDC) grant to establish a Center of Excellence in the Elimination of Disparities (CEED). This introd...

  8. Are You at Risk for Oral Cancer? What African American Men Need to Know

    Science.gov (United States)

    ... TMJ Disorders Oral Cancer Dry Mouth Burning Mouth Tooth Decay See All Oral Complications of Systemic Diseases Cancer ... for oral cancer and the importance of early detection. Multimedia: Video: Are You at Risk for Oral ...

  9. African American men with low-grade prostate cancer have increased disease recurrence after prostatectomy compared with Caucasian men

    Science.gov (United States)

    Yamoah, Kosj; Deville, Curtiland; Vapiwala, Neha; Spangler, Elaine; Zeigler-Johnson, Charnita M.; Malkowicz, Bruce; Lee, David I.; Kattan, Michael; Dicker, Adam P.; Rebbeck, Timothy R.

    2016-01-01

    PURPOSE To explore whether disparities in outcomes exist between African-American (AA) and Caucasian (CS) men with low-grade prostate cancer (PCa) and similar Cancer of the Prostate Risk Assessment post-Surgery (CAPRA-S) features following prostatectomy (RP) METHODS The overall cohort consisted of 1,265 men (234 AA, and 1,031 CS) who met National comprehensive cancer network (NCCN) criteria for low-intermediate risk PCa and underwent RP between 1990 and 2012. We first evaluated whether clinical factors were associated with adverse pathologic outcomes and freedom from biochemical failure (FFbF) using the entire cohort. Next, we studied a subset of 705 men (112 AA, and 593 CS) who had pathologic Gleason score ≤6 (low-grade disease). Using this cohort, we determined whether race impacted FFbF in men with prostatectomy-proven low-grade disease and similar CAPRA-S score. RESULTS With a median follow up time of 27 months, the overall 7-year FFbF rate was 86% vs. 79% in CS and AA men, respectively (p=0.035). There was no significant difference in ≥1 adverse pathologic features between CS vs. AA men (27% vs. 31%; P =0.35) or CAPRA-S score (p=0.28). In the subset analysis of patients with low-grade disease, AA race was associated with worse FFbF outcomes (p=0.002). Furthermore, AA race was a significant predictor of FFbF in men with low-grade disease (HR 2.01, 95%CI 1.08–3.72; p=0.029). CONCLUSIONS AA race is a predictor of worse FFbF outcomes in men with low-grade disease after RP. These results suggest that a subset of AA men with low-grade disease may benefit from more aggressive treatment. PMID:25304288

  10. Predicting Incongruence between Self-reported and Documented Colorectal Cancer Screening in a Sample of African American Medicare Recipients.

    Science.gov (United States)

    Manning, Mark; Burnett, Janice; Chapman, Robert

    2016-01-01

    Assessments of colorectal cancer (CRC) screening rates typically rely on self-reported screening data, which are often incongruent with medical records. We used multilevel models to examine health-related, socio-demographic and psychological predictors of incongruent self-reports for CRC screening among Medicare-insured African Americans (N = 3,740). Results indicated that living alone decreased, and income increased, the odds of congruently self-reporting endoscopic CRC screening. Being male and having greater number of comorbidities decreased, and having less than a high school education increased, the odds of congruently self-reported fecal occult blood tests. Living alone, age and income had the most robust effects across classifications into one of four mutually exclusive categories defined by screening status (screened/unscreened) and congruence of self-reports. The results underscore the clinical importance of gathering socio-demographic data via patient interviews, and the relevance of these data for judging the veracity of self-reported CRC screenings behaviors. PMID:25961362

  11. American Cancer Society

    Science.gov (United States)

    ... Involved Find Local ACS How the American Cancer Society Fights Childhood Cancer Advances in treatment have improved ... long lasting consequences. Learn how the American Cancer Society is working to save more lives from cancer ...

  12. Characterizing the admixed African ancestry of African Americans

    OpenAIRE

    Zakharia, Fouad; Basu, Analabha; Absher, Devin; Assimes, Themistocles L.; Go, Alan S.; Hlatky, Mark A.; Iribarren, Carlos; Knowles, Joshua W.; Li, Jun; Narasimhan, Balasubramanian; Sidney, Steven; Southwick, Audrey; Myers, Richard M.; Quertermous, Thomas; Risch, Neil

    2009-01-01

    Abstract Background Accurate, high-throughput genotyping allows the fine characterization of genetic ancestry. Here we applied recently developed statistical and computational techniques to the question of African ancestry in African Americans by using data on more than 450,000 single-nucleotide polymorphisms (SNPs) genotyped in 94 Africans of diverse geographic origins included in the...

  13. Female genital mutilation in African and African American women's literature

    Directory of Open Access Journals (Sweden)

    Darja Marinšek

    2007-12-01

    Full Text Available The article builds on the existing dispute between African and African American women writers on the competence of writing about female genital mutilation (FGM, and tries to determine the existence and nature of the differences between the writings of these two groups. The author uses comparative analysis of two popular African and African American novels, comparing their ways of describing FGM, its causes and consequences, the level ob objectivity and the style of the narrations.This is followed by a discussion on the reasons for such differences, incorporating a larger circle of both African and African American women authors, at the same time analysing the deviance within the two groups. While the differences between African American writers are not that great, as they mostly fail to present the issue from different points of view, which is often the result of their lack of direct knowledge of the topic, African authors' writing is in itself discovered to be ambivalent and not at all invariable. The reasons for such ambivalence are then discussed in greater context, focusing on the effect of the authors' personal contact with circumcision as well as their knowledge and acceptance of Western values. The author concludes by establishing the African ambivalent attitude towards FGM, which includes different aspects of the issue, as the most significant difference between their and African American writers' description of this practice.

  14. Enhanced Statistical Tests for GWAS in Admixed Populations: Assessment using African Americans from CARe and a Breast Cancer Consortium

    OpenAIRE

    Pasaniuc, Bogdan; Zaitlen, Noah; Lettre, Guillaume; Chen, Gary K.; Tandon, Arti; Kao, W. H. Linda; Ruczinski, Ingo; Fornage, Myriam; Siscovick, David S; Zhu, Xiaofeng; Larkin, Emma; Lange, Leslie A.; Cupples, L. Adrienne; Yang, Qiong; Akylbekova, Ermeg L.

    2011-01-01

    While genome-wide association studies (GWAS) have primarily examined populations of European ancestry, more recent studies often involve additional populations, including admixed populations such as African Americans and Latinos. In admixed populations, linkage disequilibrium (LD) exists both at a fine scale in ancestral populations and at a coarse scale (admixture-LD) due to chromosomal segments of distinct ancestry. Disease association statistics in admixed populations have previously consi...

  15. Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium.

    OpenAIRE

    Bogdan Pasaniuc; Noah Zaitlen; Guillaume Lettre; Chen, Gary K.; Arti Tandon; Linda Kao, W H; Ingo Ruczinski; Myriam Fornage; Siscovick, David S; Xiaofeng Zhu; Emma Larkin; Lange, Leslie A.; L Adrienne Cupples; Qiong Yang; Akylbekova, Ermeg L.

    2011-01-01

    While genome-wide association studies (GWAS) have primarily examined populations of European ancestry, more recent studies often involve additional populations, including admixed populations such as African Americans and Latinos. In admixed populations, linkage disequilibrium (LD) exists both at a fine scale in ancestral populations and at a coarse scale (admixture-LD) due to chromosomal segments of distinct ancestry. Disease association statistics in admixed populations have previously consi...

  16. Fine mapping of chromosome 15q25.1 lung cancer susceptibility in African-Americans

    OpenAIRE

    Hansen, Helen M.; Xiao, Yuanyuan; Rice, Terri; Bracci, Paige M.; Wrensch, Margaret R.; Sison, Jennette D.; Chang, Jeffery S.; Smirnov, Ivan V.; Patoka, Joseph; Seldin, Michael F; Quesenberry, Charles P.; Kelsey, Karl T.; Wiencke, John K.

    2010-01-01

    Several genome-wide association studies identified the chr15q25.1 region, which includes three nicotinic cholinergic receptor genes (CHRNA5-B4) and the cell proliferation gene (PSMA4), for its association with lung cancer risk in Caucasians. A haplotype and its tagging single nucleotide polymorphisms (SNPs) encompassing six genes from IREB2 to CHRNB4 were most strongly associated with lung cancer risk (OR = 1.3; P < 10−20). In order to narrow the region of association and identify potential c...

  17. LGBT African-American Individuals and African-American Same-Sex Couples

    OpenAIRE

    Gates, Gary J.; Kastanis, Angel

    2013-01-01

    An estimated 1,018,700 or 3.7 percent of African-American adults consider themselves lesbian, gay, bisexual or transgender (LGBT) and 34 percent of African-American same-sex couples are raising children. Currently, the estimated 84,000 African-American individuals in same-sex couples tend to live in areas where there are higher proportions of African-Americans. For example, a quarter of African-American same-sex couples live in Georgia, New York, North Carolina, and Maryland. The rep...

  18. Differential endothelial cell gene expression by African Americans versus Caucasian Americans: a possible contribution to health disparity in vascular disease and cancer

    Directory of Open Access Journals (Sweden)

    Milbauer LC

    2011-01-01

    Full Text Available Abstract Background Health disparities and the high prevalence of cardiovascular disease continue to be perplexing worldwide health challenges. This study addresses the possibility that genetic differences affecting the biology of the vascular endothelium could be a factor contributing to the increased burden of cardiovascular disease and cancer among African Americans (AA compared to Caucasian Americans (CA. Methods From self-identified, healthy, 20 to 29-year-old AA (n = 21 and CA (n = 17, we established cultures of blood outgrowth endothelial cells (BOEC and applied microarray profiling. BOEC have never been exposed to in vivo influences, and their gene expression reflects culture conditions (meticulously controlled and donor genetics. Significance Analysis of Microarray identified differential expression of single genes. Gene Set Enrichment Analysis examined expression of pre-determined gene sets that survey nine biological systems relevant to endothelial biology. Results At the highly stringent threshold of False Discovery Rate (FDR = 0, 31 single genes were differentially expressed in AA. PSPH exhibited the greatest fold-change (AA > CA, but this was entirely accounted for by a homolog (PSPHL hidden within the PSPH probe set. Among other significantly different genes were: for AA > CA, SOS1, AMFR, FGFR3; and for AA Many more (221 transcripts for 204 genes were differentially expressed at the less stringent threshold of FDR CA for 46/157 genes within that system. Conclusions Many of the genes implicated here have substantial roles in endothelial biology. Shear stress response, a critical regulator of endothelial function and vascular homeostasis, may be different between AA and CA. These results potentially have direct implications for the role of endothelial cells in vascular disease (hypertension, stroke and cancer (via angiogenesis. Also, they are consistent with our over-arching hypothesis that genetic influences stemming from ancestral

  19. Depression, Sociocultural Factors, and African American Women

    Science.gov (United States)

    Hunn, Vanessa Lynn; Craig, Carlton David

    2009-01-01

    The authors discuss depression in African American women from a sociocultural perspective, including aspects of oppression and racism that affect symptom manifestation. The authors highlight John Henryism as a coping mechanism, the history and continuing role of the African American church as a safe haven, and strategies for culturally competent…

  20. African Americans in the Early Republic.

    Science.gov (United States)

    Nash, Gary B.

    2000-01-01

    Discusses five topics on African Americans that are essential to studying United States History in the years between 1760 and 1830: (1) African Americans in the Revolutionary War ; (2) the rise of free black communities; (3) early abolitionism; (4) the spread of slavery; and (5) black resistance to slavery. (CMK)

  1. African-American Student Achievement Research Project.

    Science.gov (United States)

    Wagstaff, Mark; Melton, Jerry; Lawless, Brenda; Combs, Linda

    Data from the Texas Assessment of Academic Skills (TAAS) reveal that gains in performance for the African American student population of Region VII of the state's educational system were not keeping pace with the performance of African Americans in the rest of Texas. This study investigated practices in school districts in the region in which…

  2. Replication of GWAS “Hits” by Race for Breast and Prostate Cancers in European Americans and African Americans

    OpenAIRE

    Barnholtz-Sloan, Jill S; Raska, Paola; Rebbeck, Timothy R.; Millikan, Robert C.

    2011-01-01

    In this study, we assessed association of genome-wide association studies (GWAS) “hits” by race with adjustment for potential population stratification (PS) in two large, diverse study populations; the Carolina Breast Cancer Study (CBCS; N total = 3693 individuals) and the University of Pennsylvania Study of Clinical Outcomes, Risk, and Ethnicity (SCORE; N total = 1135 individuals). In both study populations, 136 ancestry information markers and GWAS “hits” (CBCS: FGFR2, 8q24; SCORE: JAZF1, M...

  3. Marketing a Healthy Mind, Body, and Soul: An Analysis of How African American Men View the Church as a Social Marketer and Health Promoter of Colorectal Cancer Risk and Prevention

    Science.gov (United States)

    Lumpkins, Crystal Y.; Vanchy, Priya; Baker, Tamara A.; Daley, Christine; Ndikum-Moffer, Florence; Greiner, K. Allen

    2016-01-01

    The Centers for Disease Control and Prevention ranks colorectal cancer (CRC) as the third most commonly diagnosed cancer among men in the United States; African American (AA) men are at even greater risk. The present study was from a larger study that investigates the church's role as a social marketer of CRC risk and prevention messages, and…

  4. Association of the Joint Effect of Menopause and Hormone Replacement Therapy and Cancer in African American Women: The Jackson Heart Study

    Directory of Open Access Journals (Sweden)

    Daniel Sarpong

    2011-06-01

    Full Text Available Cancer is the second leading cause of death in the US and in Mississippi. Breast cancer (BC is the most common cancer among women, and the underlying pathophysiology remains unknown, especially among African American (AA women. The study purpose was to examine the joint effect of menopause status (MS and hormone replacement therapy (HRT on the association with cancers, particularly BC using data from the Jackson Heart Study. The analytic sample consisted of 3202 women between 35 and 84 years of which 73.7% and 22.6% were postmenopausal and on HRT, respectively. There were a total of 190 prevalent cancer cases (5.9% in the sample with 22.6% breast cancer cases. Menopause (p < 0.0001, but not HRT (p = 0.6402, was independently associated with cancer. Similar results were obtained for BC. BC, cancer, hypertension, type 2 diabetes, prevalent cardiovascular disease, physical activity and certain dietary practices were all significantly associated with the joint effect of menopause and HRT in the unadjusted analyses. The family history of cancer was the only covariate that was significantly associated with cancer in the age-adjusted models. In examining the association of cancer and the joint effect of menopause and HRT, AA women who were menopausal and were not on HRT had a 1.97 (95% CI: 1.15, 3.38 times odds of having cancer compared to pre-menopausal women after adjusting for age; which was attenuated after further adjusting for family history of cancer. Given that the cancer and BC cases were small and key significant associations were attenuated after adjusting for the above mentioned covariates, these findings warrant further investigation in studies with larger sample sizes of cancer (and BC cases.

  5. MISCONCEPTIONS OF DEPRESSION IN AFRICAN AMERICANS

    Directory of Open Access Journals (Sweden)

    Zohaib eSohail

    2014-06-01

    Full Text Available Major depression is a very common disabling disorder. Although the relationship between race and depression is complex, depression affects all races, all ethnic and geographic locations as well as all age groups. The prevalence of depression in African Americans is controversial, due to the paucity of research. The deficit in the knowledge and skills in treating depression in African Americans have not been adequately addressed so far. Inadequate and insufficient data on African Americans contributes to the problems of under diagnoses, misdiagnosis and under treatment of depression. This article will highlight the existing problem of depression in Afro American with a focus on diagnostic and treatment issues.

  6. The genetic structure and history of Africans and African Americans

    OpenAIRE

    Tishkoff, Sarah A; Reed, Floyd A; Friedlaender, Françoise R; Ehret, Christopher; Ranciaro, Alessia; Froment, Alain; Hirbo, Jibril B.; Awomoyi, Agnes A; Bodo, Jean-Marie; Doumbo, Ogobara; Ibrahim, Muntaser; Juma, Abdalla T; Kotze, Maritha J.; Lema, Godfrey; Moore, Jason H.

    2009-01-01

    Africa is the source of all modern humans, but characterization of genetic variation and of relationships among populations across the continent has been enigmatic. We studied 121 African populations, four African American populations, and 60 non-African populations for patterns of variation at 1327 nuclear microsatellite and insertion/deletion markers. We identified 14 ancestral population clusters in Africa that correlate with self-described ethnicity and shared cultural and/or linguistic p...

  7. 76 FR 6519 - National African American History Month, 2011

    Science.gov (United States)

    2011-02-04

    ... imagined, African Americans have strengthened our Nation by leading reforms, overcoming obstacles, and... of African Americans to our Nation's history and identity. This year's theme, ``African Americans and... enslaved within rebellious areas, he also opened the door for African Americans to join the Union...

  8. African and non-African admixture components in African Americans and an African Caribbean population.

    Science.gov (United States)

    Murray, Tanda; Beaty, Terri H; Mathias, Rasika A; Rafaels, Nicholas; Grant, Audrey Virginia; Faruque, Mezbah U; Watson, Harold R; Ruczinski, Ingo; Dunston, Georgia M; Barnes, Kathleen C

    2010-09-01

    Admixture is a potential source of confounding in genetic association studies, so it becomes important to detect and estimate admixture in a sample of unrelated individuals. Populations of African descent in the US and the Caribbean share similar historical backgrounds but the distributions of African admixture may differ. We selected 416 ancestry informative markers (AIMs) to estimate and compare admixture proportions using STRUCTURE in 906 unrelated African Americans (AAs) and 294 Barbadians (ACs) from a study of asthma. This analysis showed AAs on average were 72.5% African, 19.6% European and 8% Asian, while ACs were 77.4% African, 15.9% European, and 6.7% Asian which were significantly different. A principal components analysis based on these AIMs yielded one primary eigenvector that explained 54.04% of the variation and captured a gradient from West African to European admixture. This principal component was highly correlated with African vs. European ancestry as estimated by STRUCTURE (r(2)=0.992, r(2)=0.912, respectively). To investigate other African contributions to African American and Barbadian admixture, we performed PCA on approximately 14,000 (14k) genome-wide SNPs in AAs, ACs, Yorubans, Luhya and Maasai African groups, and estimated genetic distances (F(ST)). We found AAs and ACs were closest genetically (F(ST)=0.008), and both were closer to the Yorubans than the other East African populations. In our sample of individuals of African descent, approximately 400 well-defined AIMs were just as good for detecting substructure as approximately 14,000 random SNPs drawn from a genome-wide panel of markers. PMID:20717976

  9. The African American Wellness Village in Portland, Ore

    OpenAIRE

    McKeever, Corliss; Koroloff, Nancy; Faddis, Collaine

    2006-01-01

    More than 80% of African Americans in Oregon reside in the Portland metropolitan area; African Americans comprise 1.7% of the state's population. Although relatively small, the African American population in the state experiences substantial health disparities. The African American Health Coalition, Inc was developed to implement initiatives that would reduce these disparities and to promote increased communication and trust between the African American community and local institutions and or...

  10. African American Culture and Hypertension Prevention

    OpenAIRE

    Peters, Rosalind M.; Aroian, Karen J.; Flack, John M.

    2006-01-01

    A qualitative study was done to explore attitudes and beliefs of African Americans regarding hypertension-preventive self-care behaviors. Five focus groups, with 34 participants, were held using interview questions loosely based on the Theory of Planned Behavior (TPB). Analysis revealed themes broadly consistent with the TPB, and also identified an overarching theme labeled “circle of culture.” The circle is a metaphor for ties that bind individuals within the larger African American communit...

  11. Conducting Molecular Epidemiological Research in the Age of HIPAA: A Multi-Institutional Case-Control Study of Breast Cancer in African-American and European-American Women

    Directory of Open Access Journals (Sweden)

    Christine B. Ambrosone

    2009-01-01

    Full Text Available Breast cancer in African-American (AA women occurs at an earlier age than in European-American (EA women and is more likely to have aggressive features associated with poorer prognosis, such as high-grade and negative estrogen receptor (ER status. The mechanisms underlying these differences are unknown. To address this, we conducted a case-control study to evaluate risk factors for high-grade ER- disease in both AA and EA women. With the onset of the Health Insurance Portability and Accountability Act of 1996, creative measures were needed to adapt case ascertainment and contact procedures to this new environment of patient privacy. In this paper, we report on our approach to establishing a multicenter study of breast cancer in New York and New Jersey, provide preliminary distributions of demographic and pathologic characteristics among case and control participants by race, and contrast participation rates by approaches to case ascertainment, with discussion of strengths and weaknesses.

  12. African names for American plants

    NARCIS (Netherlands)

    Andel, van T.R.

    2015-01-01

    African slaves brought plant knowledge to the New World, sometimes applying it to related plants they found there and sometimes bringing Old World plants with them. By tracing the linguistic parallels between names for plants in African languages and in communities descended from African slaves, pie

  13. PSA-Based Screening Outcomes, Dietary Heterocyclic Amine Exposure, and Prostate Cancer Risk in African Americans: Annual Report (Year 1 of 3)

    Energy Technology Data Exchange (ETDEWEB)

    Bogen, K T

    2006-01-18

    Prostate cancer (PC) is the second leading cause of male U.S. cancer deaths, with African-Americans having the highest rate of PC mortality worldwide, as well as more abnormal results from screening tests that correlate with current or eventual PC. A 3-year prospective clinic-based study is studying the performance of current (PSA and DRE) vs. (% free PSA) clinical biomarkers of PC risk in 400 African-American men 50 to 70 years of age who undergo PC screening in Oakland, CA (East Bay San Francisco area), as well as possible association of PC screening results for these men with their dietary exposures to the cancer-causing heterocyclic amine, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) that forms when meat is cooked. This study expands an ongoing NIH-funded study (by the same research team) to add a new %-free-PSA test, results of which will be compared with PSA/DRE results and PhIP exposures estimated by dietary interviews. For 392 men studied under the NIH protocol, an odds ratio (95% CL) of 32 (3.2, 720) for highly elevated PSA ({ge}20 ng/mL) was observed in the highest 15% vs. the lower 50% of estimated daily PhIP intakes. Approximately 100 additional men have completed participation in the expanded NIH/DOD-supported study. This study will help define the potential value of improved screening and dietary/behavioral intervention to reduce PC risk, namely, prevention of PhIP intake by avoiding overcooked meats.

  14. African American Pastors' Beliefs and Actions Regarding Childhood Incest in the African American Community

    Science.gov (United States)

    Wells, Tesia Denis

    2012-01-01

    This quantitative study sought to explore African American pastors' beliefs and actions regarding childhood incest in the African American community and their decisions to inform the proper authorities. This exploratory study was developed in order to draw both public and academic attention to the understudied phenomenon of childhood incest…

  15. African Literature and the American University.

    Science.gov (United States)

    Priebe, Richard

    While African literature appears to be firmly established in American colleges and universities, its expansion, and in some cases its continuance, is threatened by two factors: racialism and departmental conservatism. As demands for courses in black literature can be met by an increased supply of scholars in Afro-American literature, fewer schools…

  16. Genome-Wide Association Study to Identify Single Nucleotide Polymorphisms (SNPs) Associated With the Development of Erectile Dysfunction in African-American Men After Radiotherapy for Prostate Cancer

    International Nuclear Information System (INIS)

    Purpose: To identify single nucleotide polymorphisms (SNPs) associated with erectile dysfunction (ED) among African-American prostate cancer patients treated with external beam radiation therapy. Methods and Materials: A cohort of African-American prostate cancer patients treated with external beam radiation therapy was observed for the development of ED by use of the five-item Sexual Health Inventory for Men (SHIM) questionnaire. Final analysis included 27 cases (post-treatment SHIM score ≤7) and 52 control subjects (post-treatment SHIM score ≥16). A genome-wide association study was performed using approximately 909,000 SNPs genotyped on Affymetrix 6.0 arrays (Affymetrix, Santa Clara, CA). Results: We identified SNP rs2268363, located in the follicle-stimulating hormone receptor (FSHR) gene, as significantly associated with ED after correcting for multiple comparisons (unadjusted p = 5.46 x 10-8, Bonferroni p = 0.028). We identified four additional SNPs that tended toward a significant association with an unadjusted p value -6. Inference of population substructure showed that cases had a higher proportion of African ancestry than control subjects (77% vs. 60%, p = 0.005). A multivariate logistic regression model that incorporated estimated ancestry and four of the top-ranked SNPs was a more accurate classifier of ED than a model that included only clinical variables. Conclusions: To our knowledge, this is the first genome-wide association study to identify SNPs associated with adverse effects resulting from radiotherapy. It is important to note that the SNP that proved to be significantly associated with ED is located within a gene whose encoded product plays a role in male gonad development and function. Another key finding of this project is that the four SNPs most strongly associated with ED were specific to persons of African ancestry and would therefore not have been identified had a cohort of European ancestry been screened. This study demonstrates the

  17. African American Educational Leadership in the School Superintendency

    Science.gov (United States)

    Smith, Eva C.

    2013-01-01

    African American educational leadership has long been part of American education and African American activism to resist oppression. However, the field of educational leadership has rarely included the contributions of African American leaders, particularly women leaders, into mainstream leadership theory and practices. This omission is difficult…

  18. Disease Management to Promote Blood Pressure Control Among African Americans

    OpenAIRE

    Brennan, Troyen; Spettell, Claire; Villagra, Victor; Ofili, Elizabeth; McMahill-Walraven, Cheryl; Lowy, Elizabeth J.; Daniels, Pamela; Quarshie, Alexander; Mayberry, Robert

    2010-01-01

    African Americans have a higher prevalence of hypertension and poorer cardiovascular and renal outcomes than white Americans. The objective of this study was to determine whether a telephonic nurse disease management (DM) program designed for African Americans is more effective than a home monitoring program alone to increase blood pressure (BP) control among African Americans enrolled in a national health plan.

  19. Methylation of MGMT and ADAMTS14 in normal colon mucosa: biomarkers of a field defect for cancerization preferentially targeting elder African-Americans.

    Science.gov (United States)

    Alonso, Sergio; Dai, Yuichi; Yamashita, Kentaro; Horiuchi, Shina; Dai, Tomoko; Matsunaga, Akihiro; Sánchez-Muñoz, Rosa; Bilbao-Sieyro, Cristina; Díaz-Chico, Juan Carlos; Chernov, Andrei V; Strongin, Alex Y; Perucho, Manuel

    2015-02-20

    Somatic hypermethylation of the O6-methylguanine-DNA methyltransferase gene (MGMT) was previously associated with G > A transition mutations in KRAS and TP53 in colorectal cancer (CRC). We tested the association of MGMT methylation with G > A mutations in KRAS and TP53 in 261 CRCs. Sixteen cases, with and without MGMT hypermethylation, were further analyzed by exome sequencing. No significant association of MGMT methylation with G > A mutations in KRAS, TP53 or in the whole exome was found (p > 0.5 in all comparisons). The result was validated by in silico comparison with 302 CRCs from The Cancer Genome Atlas (TCGA) consortium dataset. Transcriptional silencing associated with hypermethylation and stratified into monoallelic and biallelic. We also found a significant clustering (p = 0.001) of aberrant hypermethylation of MGMT and the matrix metalloproteinase gene ADAMTS14 in normal colonic mucosa of CRC patients. This suggested the existence of an epigenetic field defect for cancerization disrupting the methylation patterns of several loci, including MGMT or ADAMTS14, that may lead to predictive biomarkers for CRC. Methylation of these loci in normal mucosa was more frequent in elder (p = 0.001) patients, and particularly in African Americans (p = 1 × 10-5), thus providing a possible mechanistic link between somatic epigenetic alterations and CRC racial disparities in North America. PMID:25638164

  20. Disparity in the Persistence of High-Risk Human Papillomavirus Genotypes Between African American and European American Women of College Age

    OpenAIRE

    Banister, Carolyn E.; Messersmith, Amy R.; Cai, Bo; Spiryda, Lisa B; Glover, Saundra H.; Pirisi, Lucia; Creek, Kim E

    2014-01-01

    Background. Cervical cancer incidence and mortality rates are higher in African Americans than in European Americans (white, non-Hispanic of European ancestry). The reasons for this disparity are not known.

  1. What about African Americans and High Blood Pressure?

    Science.gov (United States)

    ANSWERS by heart Lifestyle + Risk Reduction High Blood Pressure What About African Americans and High Blood Pressure? The prevalence of high blood pressure in African Americans is among the highest in ...

  2. Metabolic Syndrome in African Americans: Views on Making Lifestyle Changes

    OpenAIRE

    Kirkendoll, Kenya D.; Clark, Patricia C.; Grossniklaus, Daurice A.; Igho-Pemu, Priscilla; Mullis, Rebecca M.; Dunbar, Sandra B.

    2010-01-01

    This study explores African American adults’ understanding of metabolic syndrome (MetS) and their motivations for making lifestyle changes. African Americans have a greater risk for components of MetS, such as hypertension.

  3. Situational Stability and Variability in African American Racial Identity.

    Science.gov (United States)

    Shelton, J. Nicole; Sellers, Robert M.

    2000-01-01

    Investigated the stable and situational properties of African American racial identity using the Multidimensional Model of Racial Identity (MMRI). African American undergraduate students completed the Multidimensional Inventory of Black Identity, which assessed dimensions of the MMRI. African American racial identity had stable and situational…

  4. An Exploration of African American Students' Attitudes toward Online Learning

    Science.gov (United States)

    Okwumabua, Theresa M.; Walker, Kristin M.; Hu, Xiangen; Watson, Andrea

    2011-01-01

    The current work presents exploratory research findings concerning African American students' attitudes toward online learning. The Online Tutoring Attitudes Scale (OTAS; Graff, 2003) was administered to 124 African American students in a positive youth development program. Findings suggest that African American students' attitudes toward…

  5. Seeing African Americans as Competent Parents: Implications for Family Counselors

    Science.gov (United States)

    Adkison-Bradley, Carla

    2011-01-01

    One of the primary roles of parents is to guide and socialize children to make meaningful life choices. African American parents, in particular, have the additional tasks of preparing their children to thrive in an environment that has historically been hostile toward African Americans. Yet, many African American parents are often depicted as…

  6. Exposure of African-American Youth to Alcohol Advertising.

    Science.gov (United States)

    2003

    The marketing of alcohol products in African-American communities has, on occasion, stirred national controversy and met with fierce resistance from African Americans and others. Despite occasional media and community spotlights on the marketing of alcohol products in the African-American community, there has been no systematic review of the…

  7. African American Single Mothers Raising Sons: Implications for Family Therapy

    Science.gov (United States)

    Gantt, Ann L.; Greif, Geoffrey L.

    2009-01-01

    Being raised by a single mother is one factor that has been suggested as contributing to the plight of African American males. Yet few studies have focused specifically on African American single mothers' experiences with raising sons. This qualitative study explored the following questions: (1) What are the experiences of African American single…

  8. African American Students' Attitudes toward Entrepreneurship Education.

    Science.gov (United States)

    Ede, Fred O.; Panigrahi, Bhagaban; Calcich, Stephen E.

    1998-01-01

    A survey of 171 African-American students found that 72% came from nonentrepreneurial family backgrounds; only 24.5% intended to start their own businesses, there were no gender differences in entrepreneurship attitudes, and seniors and those from entrepreneurial backgrounds were more favorable toward entrepreneurship. (SK)

  9. African American College Women's Suicide Buffers.

    Science.gov (United States)

    Marion, Michelle S.; Range, Lillian M.

    2003-01-01

    To examine the relationships buffers may have with suicide ideation, 300 African American female college students completed measures of suicide ideation and buffers. Three variables accounted for a significant and unique portion of the variance in suicide ideation: family support, a view that suicide is unacceptable, and a collaborative religious…

  10. Legacy of a Pioneer African American Educator

    Science.gov (United States)

    Cazers, Gunars; Curtner-Smith, Matthew

    2013-01-01

    Purpose: The purpose was to reconstruct the historical and legendary contribution of one exemplary African American physical education teacher educator who lived and worked in the Deep South prior to and immediately following the 1954 Brown v. Board of Education court case. The following questions guided data collection and analysis: To what…

  11. African American Homeschooling Practices: Empirical Evidence

    Science.gov (United States)

    Mazama, Ama

    2016-01-01

    Despite a significant increase in scholarly interest for homeschooling, some of its most critical aspects, such as instructional daily practices, remain grossly understudied. This essay thus seeks to fill that void by presenting empirical evidence regarding the homeschooling practices of a specific group, African Americans. Most specifically, the…

  12. African American Vernacular English and Rap Music

    Institute of Scientific and Technical Information of China (English)

    胡波

    2015-01-01

    African American Vernacular English (AAVE) is the language spoken by almost 20 milion speakers al over the world. It is also used frequently in rap lyrics. Studying the origin and grammar rules of AAVE is a very important topic in today's English Language and English Teaching Studies.

  13. Educational Resilience in African American Adolescents

    Science.gov (United States)

    Cunningham, Michael; Swanson, Dena Phillips

    2010-01-01

    The purpose of this article was to examine factors within the school context that facilitates educational resilience among African American high school students. The authors expected academic self-esteem to be positively associated with future expectations (academic and general). They expected perceptions of school-based social support to have…

  14. The myth of meritocracy and African American health.

    Science.gov (United States)

    Kwate, Naa Oyo A; Meyer, Ilan H

    2010-10-01

    Recent theoretical and empirical studies of the social determinants of health inequities have shown that economic deprivation, multiple levels of racism, and neighborhood context limit African American health chances and that African Americans' poor health status is predicated on unequal opportunity to achieve the American Dream. President Obama's election has been touted as a demonstration of American meritocracy-the belief that all may obtain the American Dream-and has instilled hope in African Americans. However, we argue that in the context of racism and other barriers to success, meritocratic ideology may act as a negative health determinant for African Americans. PMID:20724679

  15. "Brothers Gonna Work It Out:" Understanding the Pedagogic Performance of African American Male Teachers Working with African American Male Students

    Science.gov (United States)

    Brown, Anthony L.

    2009-01-01

    Drawing from ethnographic data, this paper explores how African American male teachers working with African American male students performed their pedagogy. This paper highlights how teachers' understanding of African American males social and educational needs shaped their pedagogical performance. Interestingly however, teachers' performance was…

  16. An African-American family with dystonia.

    Science.gov (United States)

    Puschmann, Andreas; Xiao, Jianfeng; Bastian, Robert W; Searcy, Jill A; LeDoux, Mark S; Wszolek, Zbigniew K

    2011-08-01

    The genetic cause of late-onset focal and segmental dystonia remains unknown in most individuals. Recently, mutations in Thanatos-associated protein domain containing, apoptosis associated protein 1 (THAP1) have been described in DYT6 dystonia and associated with some cases of familial and sporadic late-onset dystonia in Caucasians. We are not aware of any previous descriptions of familial dystonia in African-Americans or reports of THAP1 mutations in African-Americans. Herein, we characterize an African-American (AA) kindred with late-onset primary dystonia, clinically and genetically. The clinical phenotype included cervical, laryngeal and hand-forearm dystonia. Symptoms were severe and disabling for several family members, whereas others only displayed mild signs. There were no accompanying motor or cognitive signs. In this kindred, age of onset ranged from 45 to 50 years and onset was frequently sudden, with symptoms developing within weeks or months. DYT1 was excluded as the cause of dystonia in this kindred. The entire genomic region of THAP1, including non-coding regions, was sequenced. We identified 13 sequence variants in THAP1, although none co-segregated with dystonia. A novel THAP1 variant (c.-237-3G>T/A) was found in 3/84 AA dystonia patient alleles and 3/212 AA control alleles, but not in 5870 Caucasian alleles. In summary, although previously unreported, familial primary dystonia does occur in African-Americans. Genetic analysis of the entire genomic region of THAP1 revealed a novel variant that was specific for African-Americans. Therefore, genetic testing for dystonia and future studies of candidate genes must take genetic background into consideration. PMID:21601506

  17. Koreans in the Hood: Conflict with African Americans.

    Science.gov (United States)

    Kim, Kwang Chung, Ed.

    The essays in this collection examine relationships between the Korean American and African American communities in Los Angeles, Chicago, and New York. The contrast between the economic power and lack of political power of Korean Americans and the political power and lack of economic power of African Americans is traced. Essays 2-5 cover Los…

  18. The landscape of recombination in African Americans

    OpenAIRE

    Anjali G Hinch; Tandon, Arti; Patterson, Nick; Song, Yunli; Rohland, Nadin; Palmer, Cameron D; Chen, Gary K.; Wang, Kai; Buxbaum, Sarah G.; Akylbekova, Meggie; Aldrich, Melinda C.; Ambrosone, Christine B.; Amos, Christopher; Bandera, Elisa V.; Berndt, Sonja I.

    2011-01-01

    Recombination, together with mutation, is the ultimate source of genetic variation in populations. We leverage the recent mixture of people of African and European ancestry in the Americas to build a genetic map measuring the probability of crossing-over at each position in the genome, based on about 2.1 million crossovers in 30,000 unrelated African Americans. At intervals of more than three megabases it is nearly identical to a map built in Europeans. At finer scales it differs significantl...

  19. How does social integration influence breast cancer control among urban African-American women? Results from a cross-sectional survey

    Directory of Open Access Journals (Sweden)

    Washington Carmen

    2008-02-01

    Full Text Available Abstract Background Although social integration is a well-established influence on health, less is known about how the specific types of social connection (social roles, social networks, and social support influence knowledge, attitudes, and practices for specific prevention goals, and how to utilize these influences in interventions with priority populations. This research examined the prevalence of social roles, networks and support among 576 urban African-American women age 45–93 in East Baltimore, Maryland, and the association of these social factors with breast cancer related knowledge, attitudes, and practices. Methods Using data from 1997–1998 in-home interviews, we developed indices of six possible social roles, social networks of family, neighborhood and church, and instrumental and emotional social support. In multivariate models adjusting for age, education, and medical care, we examined the association of each social influence on breast cancer knowledge, attitudes, screening recency and intention, and treatment preferences. Results We found substantial variation in social integration among these women, with social integration positively associated with overall health and well-being. Social roles and networks were positively associated with screening knowledge, and emotional support and church networks were positively associated with attitudes conducive to early detection and treatment. In regard to screening behaviors, family networks were associated with both screening recency and intention. Women with greater church networks and emotional support held more conservative attitudes towards lumpectomy, reconstruction, and clinical trials. Conclusion Overall, social integration is a positive influence on breast cancer control and should be utilized where possible in interventions, including identifying surrogate mechanisms for support for subgroups without existing social resources.

  20. Developing a typology of African Americans with limited literacy based on preventive health practice orientation: implications for colorectal cancer screening strategies.

    Science.gov (United States)

    Gordon, Thomas F; Bass, Sarah Bauerle; Ruzek, Sheryl B; Wolak, Caitlin; Rovito, Michael J; Ruggieri, Dominique G; Ward, Stephanie; Paranjape, Anuradha; Greener, Judith

    2014-01-01

    Preventive health messages are often tailored to reach broad sociodemographic groups. However, within groups, there may be considerable variation in perceptions of preventive health practices, such as colorectal cancer screening. Segmentation analysis provides a tool for crafting messages that are tailored more closely to the mental models of targeted individuals or subgroups. This study used cluster analysis, a psychosocial marketing segmentation technique, to develop a typology of colorectal cancer screening orientation among 102 African American clinic patients between the ages of 50 and 74 years with limited literacy. Patients were from a general internal medicine clinic in a large urban teaching hospital, a subpopulation known to have high rates of colorectal cancer and low rates of screening. Preventive screening orientation variables included the patients' responses to questions involving personal attitudes and preferences toward preventive screening and general prevention practices. A k-means cluster analysis yielded three clusters of patients on the basis of their screening orientation: ready screeners (50.0%), cautious screeners (30.4%), and fearful avoiders (19.6%). The resulting typology clearly defines important subgroups on the basis of their preventive health practice perceptions. The authors propose that the development of a validated typology of patients on the basis of their preventive health perceptions could be applicable to a variety of health concerns. Such a typology would serve to standardize how populations are characterized and would provide a more accurate view of their preventive health-related attitudes, values, concerns, preferences, and behaviors. Used with standardized assessment tools, it would provide an empirical basis for tailoring health messages and improving medical communication. PMID:24673248

  1. The Reflection of Race and Law in African American Literature

    Directory of Open Access Journals (Sweden)

    Peter Schneck

    2008-06-01

    Full Text Available Since the law has been crucial in defining and delineating the dimensions of African American experience both in slavery and in freedom, the encounter with the American legal system and its representatives has left a strong imprint on African American cultural and literary memory and expression. The article sketches out a few aspects and features which characterize the reflection of law and race in African American culture and literature.

  2. Online Health Information and Low-Literacy African Americans

    OpenAIRE

    Birru, Mehret S; Steinman, Richard A.

    2004-01-01

    African Americans with low incomes and low literacy levels disproportionately suffer poor health outcomes from many preventable diseases. Low functional literacy and low health literacy impede millions of Americans from successfully accessing health information. These problems are compounded for African Americans by cultural insensitivity in health materials. The Internet could become a useful tool for providing accessible health information to low-literacy and low-income African Americans. O...

  3. The Reflection of Race and Law in African American Literature

    OpenAIRE

    Peter Schneck

    2008-01-01

    Since the law has been crucial in defining and delineating the dimensions of African American experience both in slavery and in freedom, the encounter with the American legal system and its representatives has left a strong imprint on African American cultural and literary memory and expression. The article sketches out a few aspects and features which characterize the reflection of law and race in African American culture and literature.

  4. SUBJECTIVE MEMORY IN OLDER AFRICAN AMERICANS

    OpenAIRE

    Sims, Regina C.; Whitfield, Keith E.; Ayotte, Brian J.; Gamaldo, Alyssa A.; Edwards, Christopher L.; Allaire, Jason C.

    2011-01-01

    The current analysis examined (a) if measures of psychological well-being predict subjective memory, and (b) if subjective memory is consistent with actual memory. Five hundred seventy-nine older African Americans from the Baltimore Study of Black Aging completed measures assessing subjective memory, depressive symptomatology, perceived stress, locus of control, and verbal and working memory. Higher levels of perceived stress and greater externalized locus of control predicted poorer subjecti...

  5. Obesity and Pulmonary Function in African Americans

    OpenAIRE

    Mehari, Alem; Afreen, Samina; Ngwa, Julius; Setse, Rosanna; Thomas, Alicia N.; Poddar, Vishal; Davis, Wayne; Polk, Octavius D.; Hassan, Sheik; Thomas, Alvin V.

    2015-01-01

    Background Obesity prevalence in United States (US) adults exceeds 30% with highest prevalence being among blacks. Obesity is known to have significant effects on respiratory function and obese patients commonly report respiratory complaints requiring pulmonary function tests (PFTs). However, there is no large study showing the relationship between body mass index (BMI) and PFTs in healthy African Americans (AA). Objective To determine the effect of BMI on PFTs in AA patients who did not have...

  6. A Pooled Analysis of Body Mass Index and Mortality among African Americans

    OpenAIRE

    Cohen, Sarah S.; Park, Yikyung; Signorello, Lisa B; Patel, Alpa V; Boggs, Deborah A.; Kolonel, Laurence N; Kitahara, Cari M.; Knutsen, Synnove F; Gillanders, Elizabeth; Monroe, Kristine R.; de Gonzalez, Amy Berrington; Bethea, Traci N.; Black, Amanda; Fraser, Gary; Gapstur, Susan

    2014-01-01

    Pooled analyses among whites and East Asians have demonstrated positive associations between all-cause mortality and body mass index (BMI), but studies of African Americans have yielded less consistent results. We examined the association between BMI and all-cause mortality in a sample of African Americans pooled from seven prospective cohort studies: NIH-AARP, 1995–2009; Adventist Health Study 2, 2002–2008; Black Women's Health Study, 1995–2009; Cancer Prevention Study II, 1982–2008; Multiet...

  7. Phonological Awareness Skills in Young African American English Speakers

    Science.gov (United States)

    Mitri, Souraya Mansour; Terry, Nicole Patton

    2014-01-01

    The purpose of this study was to examine African American children's performance on a phonological awareness task that included items reflecting differences between African American English (AAE) and mainstream American English. The relationship between spoken production of AAE forms and performance on phonological awareness, vocabulary, and…

  8. The college life experiences of African American women athletes.

    Science.gov (United States)

    Sellers, R M; Kuperminc, G P; Damas, A

    1997-10-01

    The present study provides a descriptive analysis of four areas of African American women student athletes' college life experiences: academic performance; alienation and abuse; perceived social advantage as the result of athletics; and life satisfaction. Multivariate comparisons were made between the four areas of college life experiences of 154 African American women student athletes and 793 White women student athletes, 250 African American women nonathletes, and 628 African American men student athletes from a national sample of 39 NCAA Division I universities. Overall, African American women student athletes are performing adequately academically, integrating socially within the university, perceiving some social advantage as the result of being athletes, and are fairly satisfied with their life. Their experiences seem most consistent with African American women nonathletes. Results are discussed in the context of potential policy recommendations as well as the need for more research on this particular population. PMID:9485580

  9. Liver Transplantation Outcomes Among Caucasians, Asian Americans, and African Americans with Hepatitis B

    OpenAIRE

    Bzowej, Natalie; Han, Steven; Degertekin, Bulent; Keeffe, Emmet B.; Emre, Sukru; Brown, Robert; Reddy, Rajender; Lok, Anna S

    2009-01-01

    Several previous studies found that Asians transplanted for hepatitis B virus (HBV) infection had worse post-transplant outcomes than Caucasians. Data on post-transplant outcomes of African Americans and waitlist outcomes of Asian Americans and African Americans with hepatitis B are scant. The aim of this study was to compare waitlist and post-transplant outcomes among Asian Americans, African Americans, and Caucasians who had HBV-related liver disease. Data from a retrospective-prospective s...

  10. Reading the (In)visible Race: African-American Subject Representation and Formation in American Literature

    OpenAIRE

    Hollingsworth, Lauren Colleen

    2010-01-01

    This project began with the intention to examine the connection between the aesthetic and the political in American literature's construction of African-American subjectivity, or the relationship between resistance and representation in literary portrayals of the African-American subject. I was specifically interested in the moments in American literature where the convergence between aesthetic form and political practice creates a particular crisis in representation for African-American subj...

  11. Older African American Women’s Lived Experiences with Depression

    OpenAIRE

    Ward, Earlise C.; Mengesha, Maigenete; Issa, Fathiya

    2013-01-01

    Little is known about older African American women’s lived experiences with depression. What does depression mean to this group? What are they doing about their depression? Unfortunately, these questions are unanswered. This study examined older African American women’s lived experiences with depression and coping behaviours. The common sense model provided the theoretical framework for present study. Thirteen community-dwelling African American women aged 60 and older (M =71 years) participa...

  12. Transgenerational Consequences of Racial Discrimination for African American Health

    OpenAIRE

    Goosby, Bridget J.; Heidbrink, Chelsea

    2013-01-01

    Disparities in African American health remain pervasive and persist transgenerationally. There is a growing consensus that both structural and interpersonal racial discrimination are key mechanisms affecting African American health. The Biopsychosocial Model of Racism as a Stressor posits that the persistent stress of experiencing discrimination take a physical toll on the health of African Americans and is ultimately manifested in the onset of illness. However, the degree to which the health...

  13. African Americans, hypertension and the renin angiotensin system.

    OpenAIRE

    Williams, SF; Nicholas, SB; Vaziri, ND; Norris, KC

    2014-01-01

    African Americans have exceptionally high rates of hypertension and hypertension related complications. It is commonly reported that the blood pressure lowering efficacy of renin angiotensin system (RAS) inhibitors is attenuated in African Americans due to a greater likelihood of having a low renin profile. Therefore these agents are often not recommended as initial therapy in African Americans with hypertension. However, the high prevalence of comorbid conditions, such as diabetes, cardiovas...

  14. African American women and breastfeeding: an integrative literature review.

    Science.gov (United States)

    Spencer, Becky S; Grassley, Jane S

    2013-07-01

    The purpose of this article is to present a review of literature regarding factors that influence breastfeeding intentions, initiation, and duration in the African American population. Research related to health disparities experienced by African Americans in the United States, as well as research regarding the protective benefits of breastfeeding for those specific health disparities, are also presented. Community and institutional interventions and promotional campaigns aimed at increasing initiation and duration of breastfeeding in the African American population are discussed. Future research regarding African American women's breastfeeding experiences using Black feminist thought as a theoretical foundation is recommended. PMID:23445372

  15. African American legislators' perceptions of firearm violence prevention legislation.

    Science.gov (United States)

    Payton, Erica; Thompson, Amy; Price, James H; Sheu, Jiunn-Jye; Dake, Joseph A

    2015-06-01

    Firearm mortality is the leading cause of death for young African American males, however, few studies have focused on racial/ethnic minority populations and firearm violence. The National Black Caucus of State Legislators advocates for legislation that promotes the health of African Americans. Thus, the purpose of this study was to collect baseline data on African American legislators' perceptions regarding firearm violence in the African American community. A cross-sectional study of African American legislators (n = 612) was conducted to investigate the research questions. Of the 612 questionnaires mailed, 12 were not deliverable, and 170 were returned (28%). Utilizing a three wave mailing process, African American legislators were invited to participate in the study. The majority (88%) of respondents perceived firearm violence to be very serious among African Americans. Few (10%) legislators perceived that addressing legislative issues would be an effective strategy in reducing firearm violence among African Americans. The majority (72%) of legislators perceived the most effective strategy to reducing firearm violence in the African American community should focus on addressing societal issues (e.g. crime and poverty). After adjusting for the number of perceived barriers, the number of perceived benefits was a significant predictor of legislators' perceived effectiveness of firearm violence prevention legislation for 8 of the 24 potential firearm violence prevention legislative bills. PMID:25301589

  16. Squamous Cell Cancer Arising in an African American Male Cheek from Discoid Lupus: A Rare Case and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Emanuel A. Shapera

    2016-01-01

    Full Text Available A 50-year-old African American male with Discoid Lupus Erythematosus (DLE presented to the dermatology clinic for a rapidly enlarging left cheek mass. The mass failed to resolve with conservative measures. A biopsy revealed poorly differentiated Squamous Cell Carcinoma (SCC. He was referred to Head and Neck Surgery and successfully underwent a resection with free flap reconstruction. Postoperatively he did well. Squamous cell skin carcinomas arising from lesions of Discoid Lupus are rare and aggressive tumors with greater likelihood of metastases. Cases have been reported among patients with different clinical characteristics; we present a rare case arising in an African American male on the face and involving the ear.

  17. Digital Solutions for Informed Decision Making: An Academic-Community Partnership for the Development of a Prostate Cancer Decision Aid for African American Men.

    Science.gov (United States)

    Owens, Otis L; Friedman, Daniela B; Brandt, Heather M; Bernhardt, Jay M; Hébert, James R

    2016-05-01

    African American (AA) men are significantly more likely to die of prostate cancer (PrCA) than other racial groups, and there is a critical need to identify strategies for providing information about PrCA screening and the importance of informed decision making (IDM). To assess whether a computer-based IDM intervention for PrCA screening would be appropriate for AA men, this formative evaluation study examined their (1) PrCA risk and screening knowledge; (2) decision-making processes for PrCA screening; (3) usage of, attitudes toward, and access to interactive communication technologies (ICTs); and (4) perceptions regarding a future, novel, computer-based PrCA education intervention. A purposive convenience sample of 39 AA men aged 37 to 66 years in the Southeastern United States was recruited through faith-based organizations to participate in one of six 90-minute focus groups and complete a 45-item descriptive survey. Participants were generally knowledgeable about PrCA. However, few engaged in IDM with their doctor and few were informed about the associated risks and uncertainties of PrCA screening. Most participants used ICTs on a daily basis for various purposes including health information seeking. Most participants were open to a novel, computer-based intervention if the system was easy to use and its animated avatars were culturally appropriate. Because study participants had low exposure to IDM for PrCA, but frequently used ICTs, IDM interventions using ICTs (e.g., computers) hold promise for AA men and should be explored for feasibility and effectiveness. These interventions should aim to increase PrCA screening knowledge and stress the importance of participating in IDM with doctors. PMID:25563381

  18. Raising Cultural Awareness of Second Grade African American Students Using Mexican American Children's Literature

    Science.gov (United States)

    Pugh, Sandra Lyniece

    2009-01-01

    An increase in the Mexican American population within the predominantly African American community and school was the basis of this qualitative study. The purpose of the study was to introduce African American second grade students to authentic Mexican and Mexican American children's literature. Interactive read-alouds of nonfiction and realistic…

  19. Promoting Breast Cancer Screening in Rural, African American Communities: The "Science and Art" of Community Health Promotion.

    Science.gov (United States)

    Altpeter, Mary; Earp, Jo Anne L.; Shopler, Janice H.

    1998-01-01

    Social ecological theory, social-work community organization models, and health-promotion models are brought together to address ways to generate change at the individual and policy levels, and to provide guidance for community health-promotion programs. An eight-year cancer-prevention project is presented as a case study. (EMK)

  20. DETERMINANTS OF FOOD AWAY FROM HOME AMONG AFRICAN-AMERICANS

    OpenAIRE

    Pert, Calvert; Bhuyan, Sanjib

    2007-01-01

    The prominence of FAFH on consumers food expenditure raises some important questions, particularly those related to the health impact of such a trend. This is particularly true among African-Americans because on average African Americans are twice as likely as white Americans to develop Type 2 diabetes, which has been known to have some correlation with ones diet. There is a plethora of studies focusing on FAFH by American consumers. However, there are very few studies that focus exclusively ...

  1. Africans and Black Americans in the United States: Social Distance and Differential Acculturation.

    Science.gov (United States)

    Emoungu, Paul-Albert

    1992-01-01

    Presents an exploratory examination of the causes of social distance characterizing the association between Africans and African Americans. African American's perceptions about Africa and Africans are assessed through anecdotes and impressions, and thoughts and criticisms of Africans about African Americans are considered. A social science…

  2. Atrial Fibrillation and Colonic Neoplasia in African Americans.

    Directory of Open Access Journals (Sweden)

    Mehdi Nouraie

    Full Text Available Colorectal cancer (CRC and atrial fibrillation/flutter (AF share several risk factors including increasing age and obesity. However, the association between CRC and AF has not been thoroughly examined, especially in African Americans. In this study we aimed to assess the prevalence of AF and its risk factors in colorectal neoplasia in an African American.We reviewed records of 527 African American patients diagnosed with CRC and 1008 patients diagnosed with benign colonic lesions at Howard University Hospital from January 2000 to December 2012. A control group of 731 hospitalized patients without any cancer or colonic lesion were randomly selected from the same time and age range, excluding patients who had diagnosis of both CRC and/or adenoma. The presence or absence of AF was based upon ICD-9 code documentation. The prevalence of AF in these three groups was compared by multivariate logistic regression.The prevalence of AF was highest among CRC patients (10% followed by adenoma patients (7.2% then the control group (5.4%, P for trend = 0.002. In the three groups of participants, older age (P<0.008 and heart failure (P<0.001 were significantly associated with higher risk of AF. After adjusting for these risk factors, CRC (OR: 1.4(95%CI:0.9-2.2, P = 0.2 and adenoma (OR: 1.1(95%CI:0.7-1.6, P = 0.7 were not significantly associated AF compared to control group.AF is highly prevalent among CRC patients; 1 in 10 patients had AF in our study. The predictors of AF in CRC was similar to that in adenoma and other patients after adjustment for potential confounders suggesting that the increased AF risk in CRC is explained by higher prevalence of AF risk factors.

  3. It's All About Relationships: African-American and European-American Women's Hotel Management Careers

    OpenAIRE

    Farrar, Angela L.

    1996-01-01

    Among the 44000-plus general managers employed in United States' hotels in 1993, there were only 100 women, 15 African-Americans, and three African-American women. Additionally, less than 0.5 percent of corporate hospitality managers were women. Given this relative underrepresentation of European-American women and African-Americans, combined with the increasing diversity of hotel clientele and service p...

  4. Work Stress in the Family Life of African Americans.

    Science.gov (United States)

    Broman, Clifford L.

    2001-01-01

    Investigated the link between job-related stressors and family life among African Americans. Data from African Americans who participated in the America's Changing Lives survey indicated that job latitude positively affected marital harmony, and physical demands negatively affected marital harmony. Psychosocial demands, job bother, and chronic…

  5. Social Achievement Goals: Validation among Rural African American Adolescents

    Science.gov (United States)

    Jones, Martin H.; Mueller, Christian E.; Royal, Kenneth D.; Shim, Sungok Serena; Hart, Caroline O.

    2013-01-01

    Little extant research attempts to understand why rural African Americans engage in social relationships with peers in school. This is somewhat surprising as rural students' peer interactions often affect their scholastic desires, and peers can alter African Americans' academic performance. Hence, the current study examined both the…

  6. Interaction of African American Learners Online: An Adult Education Perspective

    Science.gov (United States)

    Kang, Haijun; Yang, Yang

    2016-01-01

    This study examines how various life factors and personal attributes affect African American adult learners' use of the three types of learning interaction-learner-content, learner-instructor, and learner-learner. Multivariate multiple regression analyses were used. The aggregate effect of life factors on African American adult learners' use of…

  7. Counseling Groups for African American Women: A Focus on Spirituality.

    Science.gov (United States)

    Williams, Carmen Braun; Frame, Marsha Wiggins; Green, Evelyn

    1999-01-01

    Explains cultural and spiritual traditions within African American women's experience that form the foundation for group counseling strategies. Reviews literature regarding African American women's experience in groups. Explains group interventions such as art, music, dance, imagery, journaling, and rituals that can help transcend, empower, and…

  8. African Americans Respond Poorly to Hepatitis C Treatment

    Science.gov (United States)

    Black Issues in Higher Education, 2004

    2004-01-01

    African Americans have a significantly lower response rate to treatment for chronic hepatitis C than non-Hispanic Whites, according to a new study led by Duke University Medical Center researchers. Some African Americans--19 percent--did respond to the drug combination of peginterferon alfa-2b and ribavirin. But in non-Hispanic Whites with the…

  9. 78 FR 34241 - African-American Music Appreciation Month, 2013

    Science.gov (United States)

    2013-06-06

    .... (Presidential Sig.) [FR Doc. 2013-13643 Filed 6-5-13; 11:15 am] Billing code 3295-F3 ... June 6, 2013 Part III The President Proclamation 8992--African-American Music Appreciation Month, 2013... May 31, 2013 African-American Music Appreciation Month, 2013 By the President of the United States...

  10. Asthma Management Disparities: A Photovoice Investigation with African American Youth

    Science.gov (United States)

    Evans-Agnew, Robin

    2016-01-01

    Disparities in asthma management are a burden on African American youth. The objective of this study is to describe and compare the discourses of asthma management disparities (AMDs) in African American adolescents in Seattle to existing youth-related asthma policies in Washington State. Adolescents participated in a three-session photovoice…

  11. Teaching Experiences of African American Educators in the Rural South

    Science.gov (United States)

    Polidore, Ellene; Edmonson, Stacey L.; Slate, John R.

    2010-01-01

    A scarcity of research exists regarding the voices of African American teachers who taught in the rural South. In this study, we report the life experiences, perceptions, thoughts, and feelings of three female African American educators as they pertain to their experiences teaching before, during, and after desegregation. Three female African…

  12. Language Learning and Use by African American Children.

    Science.gov (United States)

    Battle, Dolores E.

    1996-01-01

    This article reviews recent investigations of the development of phonology, morphology, semantics, and pragmatics in the development of speech and language by African American children. Clinical implications are offered to aid the distinction between normal language development using features of African American English and language disorders.…

  13. African American Youth Unemployment: Current Trends and Future Prospects.

    Science.gov (United States)

    Hunter, Herbert M.

    1990-01-01

    Examines African American employment trends compared with increases or decreases in economic growth and Federal welfare spending during the 1970s and 1980s, focusing primarily on unemployment and labor force participation rates among African American youth. Studies the impact of structural unemployment, racial discrimination, and immigration on…

  14. African American English: Implications for School Counseling Professionals

    Science.gov (United States)

    Day-Vines, Norma L.; Barto, Heather H.; Booker, Beverly L.; Smith, Kim V.; Barna, Jennifer; Maiden, Brian S.; Zegley, Linda; Felder, Monique T.

    2009-01-01

    African American English (AAE) refers to the systematic, rule-governed linguistic patterns of found among African Americans. This article provides an overview of AAE. More specifically, the article enumerates the historical underpinnings associated with AAE, identifies a representative set of AAE characteristics, reviews relevant research, and…

  15. Academic Achievement and the Third Grade African American Male

    Science.gov (United States)

    Shropshire, Delia F. B.

    2013-01-01

    The purpose of the study was to determine to what extent teaching style relates to third grade African American male academic achievement. The problem in this study addressed the factors affecting the academic achievement of the African American third grade male. This problem led the researcher to investigate the teaching styles of the…

  16. Food Group Categories of Low-Income African American Women

    Science.gov (United States)

    Lynch, Elizabeth B.; Holmes, Shane

    2011-01-01

    Objective: Describe lay food group categories of low-income African American women and assess the overlap of lay food groups and MyPyramid food groups. Design: A convenience sample of African American mothers from a low-income Chicago neighborhood performed a card-sorting task in which they grouped familiar food items into food groups. Setting:…

  17. Perceived Racism and Encouragement among African American Adults

    Science.gov (United States)

    Rowles, Joanna; Duan, Changming

    2012-01-01

    Racial discrimination has negatively affected African Americans in the United States for centuries and produced one of the most publicly recognized histories of social oppression. Extensive research has shown the deleterious effects of racism on African American people and clearly demonstrated that perceived racism and discrimination may…

  18. African Americans Who Teach German Language and Culture.

    Science.gov (United States)

    Fikes, Robert Jr.

    2001-01-01

    A large number of black scholars have pursued advanced degrees in the German language, history, and culture. Describes the history of African American interest in the German language and culture, highlighting various black scholars who have studied German over the years. Presents data on African Americans in German graduate programs and examines…

  19. African American Homeschooling and the Question of Curricular Cultural Relevance

    Science.gov (United States)

    Mazama, Ama; Lundy, Garvey

    2013-01-01

    Homeschooling, and academic interest in this phenomenon, have increased tremendously over the last decade. The surge of African American involvement in the homeschool movement has also become noticeable. However, there continues to be a general paucity of research on the motivations of African American parents that choose homeschooling. In order…

  20. 20 African-Americans Your Students Should Meet

    Science.gov (United States)

    Bardeen, Tara

    2008-01-01

    There is more to Black History Month than honoring Martin Luther King Jr. Black History Month is a time to honor the significant contributions of African-Americans throughout history. This article presents 20 super-achievers new generation of African-Americans heroes students should meet: (1) Kimberly Oliver; (2) John Lewis; (3) Rita Dove; (4)…

  1. Proxy Assessment of Health-Related Quality of Life in African American and White Respondents With Prostate Cancer

    Science.gov (United States)

    Pickard, A. Simon; Lin, Hsiang-Wen; Knight, Sara J.; Sharifi, Roohollah; Wu, Zhigang; Hung, Shih-Ying; Witt, Whitney P.; Chang, Chih-Hung; Bennett, Charles L.

    2011-01-01

    Objectives An emerging issue in the proxy literature is whether specifying different proxy viewpoints contributes to different health-related quality of life (HRQL) assessments, and if so, how might each perspective be informative in medical decision making. The aims of this study were to determine if informal caregiver assessments of patients with prostate cancer differed when prompted from both the patient perspective (proxy-patient) and their own viewpoint (proxy-proxy), and to identify factors associated with differences in proxy perspectives (ie, the intraproxy gap). Research Design and Methods Using a cross-sectional design, prostate cancer patients and their informal caregivers were recruited from urology clinics in the Jesse Brown Veterans Affairs Healthcare System in Chicago. Dyads assessed HRQL using the EQ-5D visual analog scale (VAS) and EORTC QLQ-C30. Results Of 87 dyads, most caregivers were female (83%) and were spouses/partners (58%). Mean difference scores between proxy-patient and proxy-proxy perspectives were statistically significant for QLQ-C30 physical and emotional functioning, and VAS (all P < 0.05), with the proxy-patient perspective closer to patient self-report. Emotional functioning had the largest difference, mean 6.0 (SD 12.8), an effect size = 0.47. Factors weakly correlated with the intraproxy gap included relationship (spouse) and proxy gender for role functioning, and health literacy (limited/functional) for physical functioning (all P < 0.05, 0.20 < r < 0.35). Conclusions Meaningful differences between proxy-patient and proxy-proxy perspectives on mental health were consistent with a conceptual framework for understanding proxy perspectives. Prompting different proxy viewpoints on patient health could help clinicians identify patients who may benefit from clinical intervention. PMID:19169118

  2. Africans in the American Labor Market.

    Science.gov (United States)

    Elo, Irma T; Frankenberg, Elizabeth; Gansey, Romeo; Thomas, Duncan

    2015-10-01

    The number of migrants to the United States from Africa has grown exponentially since the 1930s. For the first time in America's history, migrants born in Africa are growing at a faster rate than migrants from any other continent. The composition of African-origin migrants has also changed dramatically: in the mid-twentieth century, the majority were white and came from only three countries; but today, about one-fifth are white, and African-origin migrants hail from across the entire continent. Little is known about the implications of these changes for their labor market outcomes in the United States. Using the 2000-2011 waves of the American Community Survey, we present a picture of enormous heterogeneity in labor market participation, sectoral choice, and hourly earnings of male and female migrants by country of birth, race, age at arrival in the United States, and human capital. For example, controlling a rich set of human capital and demographic characteristics, some migrants-such as those from South Africa/Zimbabwe and Cape Verde, who typically enter on employment visas-earn substantial premiums relative to other African-origin migrants. These premiums are especially large among males who arrived after age 18. In contrast, other migrants-such as those from Sudan/Somalia, who arrived more recently, mostly as refugees-earn substantially less than migrants from other African countries. Understanding the mechanisms generating the heterogeneity in these outcomes-including levels of socioeconomic development, language, culture, and quality of education in countries of origin, as well as selectivity of those who migrate-figures prominently among important unresolved research questions. PMID:26304845

  3. Marketing a Healthy Mind, Body, and Soul: An Analysis of How African American Men View the Church as a Social Marketer and Health Promoter of Colorectal Cancer Risk and Prevention.

    Science.gov (United States)

    Lumpkins, Crystal Y; Vanchy, Priya; Baker, Tamara A; Daley, Christine; Ndikum-Moffer, Florence; Greiner, K Allen

    2016-08-01

    The Centers for Disease Control and Prevention ranks colorectal cancer (CRC) as the third most commonly diagnosed cancer among men in the United States; African American (AA) men are at even greater risk. The present study was from a larger study that investigates the church's role as a social marketer of CRC risk and prevention messages, and whether religiously targeted and tailored health promotion materials will influence screening outcome. We used an integrated theoretical approach to explore participants' perceptions of CRC risk and prevention and how promotion messages should be developed and socially marketed by the church. Six focus groups were conducted with men from predominately AA churches in the Midwest. Themes from focus group discussions showed participants lacked knowledge about CRC, feared cancer diagnosis, and feared the procedure for screening. Roles of masculinity and the mistrust of physicians were also emergent themes. Participants did perceive the church as a trusted marketer of CRC but believed that promotional materials should be cosponsored and codeveloped by reputable health organizations. Employing the church as a social marketer of CRC screening promotion materials may be useful in guiding health promotions and addressing barriers that are distinct among African American men. PMID:26424748

  4. Gendered Resource Returns: African American Institutions and Political Engagement

    OpenAIRE

    Robnett, Belinda

    2007-01-01

    While numerous studies discuss the importance of black churches and race-based organizations to African American political participation, few of them systematically analyze the gendered nature of such engagement. Employing data from the 1994 National Black Politics Survey, this study compares the influence of church-based activities and race-based organizational participation on African American men’s and women’s electoral and non-electoral political participation, and finds that 1) African ...

  5. African Americans,hypertension and the renin angiotensin system

    Institute of Scientific and Technical Information of China (English)

    Sandra; F; Williams; Susanne; B; Nicholas; Nosratola; D; Vaziri; Keith; C; Norris

    2014-01-01

    African Americans have exceptionally high rates of hypertension and hypertension related complications. It is commonly reported that the blood pressure lowering efficacy of renin angiotensin system(RAS) inhibitors is attenuated in African Americans due to a greater likelihood of having a low renin profile. Therefore these agents are often not recommended as initial therapy in African Americans with hypertension. However, the high prevalence of comorbid conditions, such as diabetes, cardiovascular and chronic kidney disease makes treatment with RAS inhibitors more compelling. Despite lower circulating renin levels and a less significant fall in blood pressure in response to RAS inhibitors in African Americans, numerous clinical trials support the efficacy of RAS inhibitors to improve clinical outcomes in this population, especially in those with hypertension and risk factors for cardiovascular and related diseases. Here, we discuss the rationale of RAS blockade as part of a comprehensive approach to attenuate the high rates of premature morbidity and mortality associated with hypertension among African Americans.

  6. Chronic Pain in Older African American Grandparent Caregivers.

    Science.gov (United States)

    Booker, Staja Q

    2016-06-01

    African American grandparent caregiving is increasing, and evidence shows that grandparent caregiving influences health and its management. As older adults age, their potential of experiencing chronic pain increases, and this is profound given that physiological research shows that African Americans, aside from aging, may have a predisposition for developing chronic pain. Research shows older African Americans experience significant chronic pain, but few have discussed the implications of managing chronic pain in older African Americans who have added parental responsibility. Many older African Americans receive home healthcare services and there is a unique role for home healthcare clinicians in caring for this vulnerable population. This article discusses the impact of pain on caregiving, challenges in pain management, and practice and policy implications to assist home healthcare clinicians maintain the safety and protection of both the older grandparent and grandchildren. PMID:27243429

  7. Tenancy and African American Marriage in the Postbellum South.

    Science.gov (United States)

    Bloome, Deirdre; Muller, Christopher

    2015-10-01

    The pervasiveness of tenancy in the postbellum South had countervailing effects on marriage between African Americans. Tenancy placed severe constraints on African American women's ability to find independent agricultural work. Freedwomen confronted not only planters' reluctance to contract directly with women but also whites' refusal to sell land to African Americans. Marriage consequently became one of African American women's few viable routes into the agricultural labor market. We find that the more counties relied on tenant farming, the more common was marriage among their youngest and oldest African American residents. However, many freedwomen resented their subordinate status within tenant marriages. Thus, we find that tenancy contributed to union dissolution as well as union formation among freedpeople. Microdata tracing individuals' marital transitions are consistent with these county-level results. PMID:26223562

  8. Conceptualizing the African American Mathematics Teacher as a Key Figure in the African American Education Historical Narrative

    Science.gov (United States)

    Clark, Lawrence M.; Jones Frank, Toya; Davis, Julius

    2013-01-01

    Background/Context: Historians and researchers have documented and explored the work and role of African American teachers in the U.S. educational system, yet there has been limited attention to the specific work, role, and experiences of African American mathematics teachers. To meaningfully and responsibly conceptualize the role of African…

  9. Attachment Style Differences and Depression in African American and European American College Women: Normative Adaptations?

    Science.gov (United States)

    Cooley, Eileen L.; Garcia, Amber L.

    2012-01-01

    This study examined ethnic differences in attachment styles and depression among African American and European American college women. African American women reported less favorable views of others, which suggests that attachment styles emphasizing caution in relationships may be normative and adaptive for these women. There were no differences…

  10. Is Native American R Y-Chromosome of African Origin?

    OpenAIRE

    Clyde Winters

    2011-01-01

    Controversey surrounds the phylogeography and origin of the R haplotype among Native Americans. Some researchers have suggested that Europeans spread this haplotype among Native Americans. The purpose of this study was to determine the origin of the R-M173 y-chromosome among Native Americans . It is the third most frequent y-chromosome possessed by Native Americans. Native Americans with the highest frequency of R-M173 haplotypes like the Ojibwa and Seminoles mated frequently with African mal...

  11. Americans' view of cancer.

    Science.gov (United States)

    Johnson, J; Blanchard, J; Harvey, C

    2000-01-01

    This paper presents the concept of the town hall meeting and discusses how it can be used as a forum for those who have been touched by cancer. It can be a platform for people to express their views about cancer, not only in the community but also nationally. Empowerment is the hallmark of a town hall meeting. Those who are in leadership positions in health care and elected officials and community leaders are given the opportunity to hear the opinions of people who represent a broad-based constituency of individuals affected by cancer. The idea of holding a town hall meeting was first introduced in the cancer community by the National Coalition for Cancer Survivorship NCCS) as a means of identifying issues, exchanging information and considering creative solutions to problems. The first town hall meeting was held in 1994 in conjunction with the NCCS annual assembly. Since then, utilizing the guidelines set forth by the NCCS, 30 or more town hall meetings have been held across the United States. Cancer survivors have, by and large, been responsible for garnering the necessary support for conducting a town hall in their local area. Organizations such as the American Cancer Society, the Leukemia Society of America, hospitals, clinics, pharmaceutical and healthcare companies and also noncancer groups, such as the YMCA, churches, and radio/T.V. stations, join with the cancer survivors in organizing the meeting, planning related displays, and advertising the event. In 1998, seven town hall meetings were sponsored jointly by OnCare and NCCS in advance and support of the upcoming THE MARCH- Coming Together To Conquer Cancer, a national rally held in Washington, D.C. in September 1998. Attendees at the meetings included not only cancer survivors and their families, but also healthcare professionals, local and state legislators, community leaders and the media. Results of the 1998 town hall meetings are discussed and compared with the topics identified during the meetings

  12. Dietary Fat Intake among Urban, African American Adolescents

    OpenAIRE

    Di NOIA, JENNIFER; Schinke, Steven P.; Contento, Isobel R.

    2007-01-01

    This study examined commonly consumed high-fat food sources to estimate dietary fat intake among 314 urban, African American adolescents (mean age (SD) = 12.57 (.98) years; 66% female; 91% African American non-Hispanic; and 9% African American Hispanic). Youths’ fat intake was measured using the Block Fat Screener. Most (77%) participants had diets very high in fat (i.e., 40% to 50% of energy). Mean frequencies of consumption revealed youths’ preferences for the following high-fat food items:...

  13. Utilization of Mammography Services among Elderly Rural and Urban African American Women

    Science.gov (United States)

    Agho, Augustine O; Mosley, Barbara W; Rivers, Patrick A; Parker, Shandowyn

    2007-01-01

    Purpose: This study was a two-year educational intervention and research project aimed at increasing the awareness of breast cancer and the utilization of Clinical Breast Examination (CBE) services and Self-Breast Examination (SBE) among elderly rural and urban African American women who are Medicare beneficiaries. Design: The study was…

  14. Recruiting intergenerational African American males for biomedical research Studies: a major research challenge.

    Science.gov (United States)

    Byrd, Goldie S; Edwards, Christopher L; Kelkar, Vinaya A; Phillips, Ruth G; Byrd, Jennifer R; Pim-Pong, Dora Som; Starks, Takiyah D; Taylor, Ashleigh L; Mckinley, Raechel E; Li, Yi-Ju; Pericak-Vance, Margaret

    2011-06-01

    The health and well-being of all individuals, independent of race, ethnicity, or gender, is a significant public health concern. Despite many improvements in the status of minority health, African American males continue to have the highest age-adjusted mortality rate of any race-sex group in the United States. Such disparities are accounted for by deaths from a number of diseases such as diabetes, human immunodeficiency virus (HIV), cancer, and cardiovascular disease, as well as by many historical and present social and cultural constructs that present as obstacles to better health outcomes. Distrust of the medical community, inadequate education, low socioeconomic status, social deprivation, and underutilized primary health care services all contribute to disproportionate health and health care outcomes among African Americans compared to their Caucasian counterparts. Results of clinical research on diseases that disproportionately affect African American males are often limited in their reliability due to common sampling errors existing in the majority of biomedical research studies and clinical trials. There are many reasons for underrepresentation of African American males in clinical trials, including their common recollection and interpretation of relevant historical of biomedical events where minorities were abused or exposed to racial discrimination or racist provocation. In addition, African American males continue to be less educated and more disenfranchised from the majority in society than Caucasian males and females and their African American female counterparts. As such, understanding their perceptions, even in early developmental years, about health and obstacles to involvement in research is important. In an effort to understand perspectives about their level of participation, motivation for participation, impact of education, and engagement in research, this study was designed to explore factors that impact their willingness to participate. Our

  15. African American Women's Breastfeeding Experiences: Cultural, Personal, and Political Voices.

    Science.gov (United States)

    Spencer, Becky; Wambach, Karen; Domain, Elaine Williams

    2015-07-01

    The low rate of breastfeeding among African American women in the United States is a poorly understood, persistent disparity. Our purpose in this study was to gain an understanding of how African American women experience breastfeeding in the context of their day-to-day lives. The Sequential-Consensual Qualitative Design (SCQD), a 3-stage qualitative methodology aimed at exploring the cultural, personal, and political context of phenomena, was used to explore the experiences of African American women who felt successful with breastfeeding. An integration of qualitative content analysis and Black feminist theory was used to analyze the data. Themes that emerged from Stage-2 data analysis included self-determination, spirituality and breastfeeding, and empowerment. In Stage 3 of the study, participant recommendations regarding breastfeeding promotion and support initiatives for African American breastfeeding were categorized into three themes, including engaging spheres of influence, sparking breastfeeding activism, and addressing images of the sexual breast vs. the nurturing breast. PMID:25288408

  16. Urbanisation and coronary heart disease mortality among African Americans in the US South.

    OpenAIRE

    Barnett, E; Strogatz, D; Armstrong, D; Wing, S

    1996-01-01

    STUDY OBJECTIVE: Despite significant declines since the late 1960s, coronary mortality remains the leading cause of death for African Americans. African Americans in the US South suffer higher rates of cardiovascular disease than African Americans in other regions; yet the mortality experiences of rural-dwelling African Americans, most of whom live in the South, have not been described in detail. This study examined urban-rural differentials in coronary mortality trends among African American...

  17. Spirit, Space & Survival: African American Women in (White) Academe.

    Science.gov (United States)

    James, Joy, Ed.; Farmer, Ruth, Ed.

    This volume presents the stories of 11 African American women working in higher education and confronting racist and sexist practices. The chapters have the following titles and authors: (1) "Mixed Blood, New Voices" (Kaylynn Sullivan Two Trees); (2) "Carrying On" (Joyce Scott); (3) "African Philosophy, Theory, and 'Living Thinkers'" (Joy James);…

  18. Grass Roots: African Origins of an American Art

    OpenAIRE

    E. N. Anderson

    2010-01-01

    Review of Grass Roots: African Origins of an American Art. Dale Rosengarten, Theodore Rosengarten, and Enid Schildkrout, eds. 2008. Museum for African Art, New York. Distributed by University of Washington Press, Seattle. Pp. 269, copiously illustrated in black-and-white and color. ISBN (cloth) 978-0-945802-50-1, (paper) 978-0-945802-51-8.

  19. Informal learning in SME majors for African American female undergraduates

    OpenAIRE

    Ezella McPherson

    2014-01-01

    This research investigates how eight undergraduate African American women in science, math, and engineering (SME) majors accessed cultural capital and informal science learning opportunities from preschool to college. It uses the multiple case study methodological approach and cultural capital as the framework to better understand their opportunities to engage in free-choice science learning. The article demonstrates that African American women have access to cultural capital and informal sci...

  20. Academic Growth Trajectories and Family Relationships among African American Youth

    OpenAIRE

    Dotterer, Aryn M.; Lowe, Katie; McHale, Susan M.

    2013-01-01

    This study explored trajectories of African American youths’ academic functioning and assessed whether changes in parent-adolescent relationships were associated with changes in youths’ academic functioning. The data were drawn from a three-year longitudinal study of gender socialization and development in two-parent African American families and included 197 families. Findings revealed gender differences in achievement trajectories and indicated that boys not only had lower levels of academi...

  1. Critical Inquiry into Urban African American Students' Perceptions of Engineering

    OpenAIRE

    Denson, Cameron D.; Avery, Zanj K.; Schell, John W.

    2007-01-01

    The purpose of this study was to critically examine the perceptions that African- American high school students have towards engineering. A qualitative research design using criterion sampling and snowballing was used to select seven African-American students from urban high schools to participate in the research. Semi-structured interviews were used to collect data from participants attending urban high schools on the east and west coast. Using Critical Race Theory (CRT) as the theoretical f...

  2. HIV Stigma and Social Support among African Americans

    OpenAIRE

    Galvan, Frank H.; Davis, E. Maxwell; Banks, Denedria; Bing, Eric G.

    2008-01-01

    HIV-related stigma and discrimination negatively impact African Americans living with HIV. Social support theory hypothesizes that social support can serve to protect individuals against the negative effects of stressors, such as discrimination, by leading them to interpret stressful occasions less negatively. This study sought to examine the relationship between perceived social support and perceived HIV stigma among HIV-positive African Americans. A cross-sectional convenience sample of 283...

  3. An Empirical Examination of Inter-Ethnic Stereotypes: Comparing Asian American and African American Employees.

    Science.gov (United States)

    Gilbert, Jackie; Carr-Ruffino, Norma; Ivancevich, John M.; Lownes-Jackson, Millicent

    2003-01-01

    Undergraduates (n=127) read career histories (including photographs) of fictitious employees in a 2x2x2 design depicting job type (engineer/human resources), ethnicity (Asian or African American), and gender, with the same qualifications and performance information. African-American males were rated most negatively on work characteristics;…

  4. Facts about Peripheral Arterial Disease (P.A.D.) for African Americans

    Science.gov (United States)

    ... About Peripheral Arterial Disease (P.A.D.) for African Americans One in every 20 Americans over the age ... stroke. P.A.D. is more common in African Americans than any other racial or ethnic group. This ...

  5. Community Engaged Lifestyle Modification Research: Engaging Diabetic and Prediabetic African American Women in Community-Based Interventions

    OpenAIRE

    Blanks, Starla Hairston; Treadwell, Henrie; Bazzell, Anya; Graves, Whitney; Osaji, Olivia; Dean, Juanita; James T. McLawhorn; Stroud, Jareese Lee

    2016-01-01

    Purpose. The I Am Woman (IAW) Program is a community-based, culturally responsive, and gender-specific nutrition, obesity, and diabetes educational prevention program designed for African American women (AAW). Chronic nutrition-related health conditions such as excess body weight, diabetes mellitus, cardiovascular disease, and some forms of cancer are common among many African American women. Methods. IAW engaged AAW at risk for such deleterious health conditions by developing a health educat...

  6. Obesity and Pulmonary Function in African Americans.

    Directory of Open Access Journals (Sweden)

    Alem Mehari

    Full Text Available Obesity prevalence in United States (US adults exceeds 30% with highest prevalence being among blacks. Obesity is known to have significant effects on respiratory function and obese patients commonly report respiratory complaints requiring pulmonary function tests (PFTs. However, there is no large study showing the relationship between body mass index (BMI and PFTs in healthy African Americans (AA.To determine the effect of BMI on PFTs in AA patients who did not have evidence of underlying diseases of the respiratory system.We reviewed PFTs of 339 individuals sent for lung function testing who had normal spirometry and lung diffusion capacity for carbon monoxide (DLCO with wide range of BMI.Functional residual capacity (FRC and expiratory reserve volume (ERV decreased exponentially with increasing BMI, such that morbid obesity resulted in patients breathing near their residual volume (RV. However, the effects on the extremes of lung volumes, at total lung capacity (TLC and residual volume (RV were modest. There was a significant linear inverse relationship between BMI and DLCO, but the group means values remained within the normal ranges even for morbidly obese patients.We showed that BMI has significant effects on lung function in AA adults and the greatest effects were on FRC and ERV, which occurred at BMI values < 30 kg/m2. These physiological effects of weight gain should be considered when interpreting PFTs and their effects on respiratory symptoms even in the absence of disease and may also exaggerate existing lung diseases.

  7. Is Native American R Y-Chromosome of African Origin?

    Directory of Open Access Journals (Sweden)

    Clyde Winters

    2011-11-01

    Full Text Available Controversey surrounds the phylogeography and origin of the R haplotype among Native Americans. Some researchers have suggested that Europeans spread this haplotype among Native Americans. The purpose of this study was to determine the origin of the R-M173 y-chromosome among Native Americans . It is the third most frequent y-chromosome possessed by Native Americans. Native Americans with the highest frequency of R-M173 haplotypes like the Ojibwa and Seminoles mated frequently with African males. Our findings indicate that the African male, Native American female pattern of mating in the United States probably led to the introduction and spread of R-M173 among Native Americans during slavery.

  8. Concordance Rates for Cognitive Impairment among Older African American Twins

    OpenAIRE

    Whitfield, Keith E.; Kiddoe, Jared; Gamaldo, Alyssa; Andel, Ross; Christopher L Edwards

    2009-01-01

    We calculated concordance rates and heritability for cognitive impairment in 95 same-sexed pairs of African American twins from the Carolina African American Twin Study on Aging (CAATSA). The average age of the sample was 59.6 yrs (SD = 8.6 years, range 50–88 years) and 60% of the sample was female. The Telephone Interview for Cognitive Status (TICS) was used in the assessment of cognitive impairment. We lowered the cutoff for cognitive impairment based on our previous research with African A...

  9. African Self-Consciousness and Health-Promoting Behaviors among African American College Students.

    Science.gov (United States)

    Thompson, Shawn N.; Chambers, John W., Jr.

    2000-01-01

    Investigated three models of relationships between African self-consciousness, health consciousness, and health-promoting behaviors among African American college students. The models included the mediator model, moderator model, and independent model. Surveys of 80 students supported the independent model, suggesting that African…

  10. Not To Repeat History: Racialization and Combinatory Textuality in Contemporary Asian American and African American Experimental Writing

    OpenAIRE

    Chen, Christopher Sze-Ming

    2011-01-01

    This dissertation, Not To Repeat History: Racialization and Combinatory Textuality in Contemporary Asian American and African American Experimental Writing, examines the relationship between textual strategies and political imagination at work in Asian American and African American experimental writers Nathaniel Mackey, Myung Mi Kim, and Ed Roberson. Providing one of the first cross-cultural studies of contemporary Asian American and African American experimental writing, I contend that these...

  11. Teachers' Perceptions of African American Principals' Leadership in Urban Schools.

    Science.gov (United States)

    Jones, Cornel

    2002-01-01

    Examined the perceptions of teachers of color and European American teachers regarding their African American principals' ability to lead successful urban schools. Survey and interview data indicated that in the areas of image management and relationship development, the two groups perceived their principals' leadership differently.(SM)

  12. 77 FR 33595 - African-American Music Appreciation Month, 2012

    Science.gov (United States)

    2012-06-07

    ... two hundred and thirty-sixth. (Presidential Sig.) [FR Doc. 2012-13944 Filed 6-6-12; 8:45 am] Billing... Documents#0;#0; #0; #0;Title 3-- #0;The President ] Proclamation 8832 of June 1, 2012 African-American Music... piece of American culture, music offers a vibrant soundtrack to the story of our people and our...

  13. An analysis of African American Vernacular English in Music

    Institute of Scientific and Technical Information of China (English)

    PAN Chen-yang

    2014-01-01

    AAVE is a form of American English spoken primarily by African Americans. Although an AAVE speaker's dialect may exhibit regional variation, there are still many salient features. The relationship between Black Music and Standard American Eng-lish is a reflection of the special situation of the mutual influence and infiltration of the African-American sub-culture and the main-stream American culture. African-American sub-culture is shaped under pressure from the main-stream culture, and af-fected the latter to so great an extent that African-American sub-culture has been identified as one of the most important feature of American culture. The origin and development of Black Music are closely related to the cultural life of the Blacks. Because of its innate cultural connotation and the musical feature such as lively rhythm, fast talking, omission of pronunciation, full of ob-scene language and rhyme, all the features mentioned above help to have a great effect on the development of the AAVE.

  14. 75 FR 32075 - African-American Music Appreciation Month, 2010

    Science.gov (United States)

    2010-06-07

    ... indelible contributions to our Nation and our world. Throughout our history, African-American music has... traces our Nation's history. These quintessentially American styles of music have helped provide a common... America the two hundred and thirty-fourth. (Presidential Sig.) [FR Doc. 2010-13660 Filed 6-4-10; 8:45...

  15. Genetic Ancestry-Smoking Interactions and Lung Function in African Americans: A Cohort Study

    OpenAIRE

    Aldrich, Melinda C.; Kumar, Rajesh; Colangelo, Laura A.; Williams, L. Keoki; Sen, Saunak; Kritchevsky, Stephen B.; Meibohm, Bernd; Galanter, Joshua; Hu, Donglei; Gignoux, Christopher R.; Liu, Yongmei; Harris, Tamara B.; Ziv, Elad; Zmuda, Joseph; Garcia, Melissa

    2012-01-01

    Background Smoking tobacco reduces lung function. African Americans have both lower lung function and decreased metabolism of tobacco smoke compared to European Americans. African ancestry is also associated with lower pulmonary function in African Americans. We aimed to determine whether African ancestry modifies the association between smoking and lung function and its rate of decline in African Americans. Methodology/Principal Findings We evaluated a prospective ongoing cohort of 1,281 Afr...

  16. Disease Messaging in Churches: Implications for Health in African-American Communities.

    Science.gov (United States)

    Harmon, Brook E; Chock, Marci; Brantley, Elizabeth; Wirth, Michael D; Hébert, James R

    2016-08-01

    Using the right messaging strategies, churches can help promote behavior change. Frequencies of disease-specific messages in 21 African-American churches were compared to overall and cancer-specific mortality and morbidity rates as well as church-level variables. Disease messages were found in 1025 of 2166 items. Frequently referenced topics included cancer (n = 316), mental health conditions (n = 253), heart disease (n = 246), and infectious diseases (n = 220). Messages for lung and colorectal cancers appeared at low frequency despite high mortality rates in African-American communities. Season, church size, and denomination showed significant associations with health messages. Next steps include testing messaging strategies aimed at improving the health of churchgoing communities. PMID:26296703

  17. Feature Articles on African Americans in Sports Illustrated in the 1990s

    Science.gov (United States)

    Angela Lumpkin

    2009-01-01

    This descriptive study examined whether the coverage of African Americans in the feature articles in Sports Illustrated during the 1990s was representative of their participation levels. Nearly half of the articles featured European Americans; about one-third featured African Americans. More African Americans were featured in basketball, boxing,…

  18. Informal learning in SME majors for African American female undergraduates

    Directory of Open Access Journals (Sweden)

    Ezella McPherson

    2014-11-01

    Full Text Available This research investigates how eight undergraduate African American women in science, math, and engineering (SME majors accessed cultural capital and informal science learning opportunities from preschool to college. It uses the multiple case study methodological approach and cultural capital as the framework to better understand their opportunities to engage in free-choice science learning. The article demonstrates that African American women have access to cultural capital and informal science learning inside and outside of home and school environments in P-16 settings. In primary and secondary schools, African American girls acquire cultural capital and access to free-choice science learning in the home environment, museums, science fairs, student organizations and clubs. However, in high school African American female teenagers have fewer informal science learning opportunities like those such as those provided in primary school settings. In college, cultural capital is transmitted through informal science learning that consisted of involvement in student organizations, research projects, seminars, and conferences. These experiences contributed to their engagement and persistence in SME fields in K-16 settings. This research adds to cultural capital and informal science learning research by allowing scholars to better understand how African American women have opportunities to learn about the hidden curriculum of science through informal science settings throughout the educational pipeline.

  19. The Diabetic Health of African American Grandmothers Raising their Grandchildren

    Science.gov (United States)

    Carthron, Dana L.; Busam, Maria Rivera

    2016-01-01

    PURPOSE The purpose of this study is to compare the health of primary caregiving African American grandmothers with diabetes with African American women with diabetes who were not primary caregivers. DESIGN Using a comparative, descriptive, cross-sectional design, 34 African American primary caregiving grandmothers were compared with 34 non-caregiving women with diabetes mellitus; women aged 55–75 years were recruited for this study throughout the central Arkansas. METHODS To measure the overall health, data on blood pressure, body mass index measurements, HbA1c levels, total cholesterol, and urine protein and creatinine levels were collected from all the participants. RESULTS Statistically significant differences between the caregivers and non-caregivers groups in systolic pressure (t = −3.42, P = 0.001) and diastolic pressure (t = −3.790, P = 0.000) and urine protein (W = 294.00, P = 0.000) were noted. Additionally, a clinically significant difference in HbA1c was noted between groups. CONCLUSION Differences in systolic and diastolic pressures, urine protein, and clinically significant differences in HbA1c suggest that African American primary caregiving grandmothers with diabetes mellitus may have more difficulty in maintaining their diabetic health than non-caregiving African American women. PMID:27398044

  20. Transthyretin isoleucine-122 mutation in African and American blacks.

    Science.gov (United States)

    Afolabi, I; Hamidi Asl, K; Nakamura, M; Jacobs, P; Hendrie, H; Benson, M D

    2000-06-01

    The gene frequency of the transthyretin (TTR) mutation (Val122Ile) was studied in African and African-American populations. The African populations analyzed included the Zulu and Xhosa of South Africa, and Yorubas from the city of Ibadan, Nigeria. The African-American population included patients at the Veterans Affairs (VA) Medical Center, Indianapolis, and newborns from a local hospital in Indianapolis. The Val122Ile TTR mutation was identified in 1 of 55 Zulu, 0 of 34 Xhosa, 0 of 9 Nigerian subjects, 5 of 51 Veteran patients, and 3 of 103 newborns. Assuming the 2.91% prevalence in newborns to be the norm, there is a significant increased prevalence in the VA patient population. PMID:10842715

  1. Brief report: Explaining differences in depressive symptoms between African American and European American adolescents.

    Science.gov (United States)

    Mrug, Sylvie; King, Vinetra; Windle, Michael

    2016-01-01

    African American adolescents report more depressive symptoms than their European American peers, but the reasons for these differences are poorly understood. This study examines whether risk factors in individual, family, school, and community domains explain these differences. African American and European American adolescents participating in the Birmingham Youth Violence Study (N = 594; mean age 13.2 years) reported on their depressive symptoms, pubertal development, aggressive and delinquent behavior, connectedness to school, witnessing violence, and poor parenting. Primary caregivers provided information on family income and their education level, marital status, and depression, and the adolescents' academic performance. African American adolescents reported more depressive symptoms than European American participants. Family socioeconomic factors reduced this difference by 29%; all risk factors reduced it by 88%. Adolescents' exposure to violence, antisocial behavior, and low school connectedness, as well as lower parental education and parenting quality, emerged as significant mediators of the group differences in depressive symptoms. PMID:26580552

  2. Sexual health communication within religious African-American families.

    Science.gov (United States)

    Williams, Terrinieka T; Pichon, Latrice C; Campbell, Bettina

    2015-01-01

    While research suggests youth prefer parents and family members to serve as the primary sources of sexual health information, fear and discomfort around discussing sex with their parents may leave youth misinformed and underinformed. This study explored sexual heath communication within religious African-American families. Thirty adolescents participated in four focus groups, and 19 adults and 30 adolescents participated in six focus groups, at two predominantly African-American Christian churches in Flint, MI. All data were analyzed inductively using a constant comparison approach. Nearly all participants reported attending church weekly. Three themes emerged and are described: initiating sex talks, using mistakes as teaching tools, and clarifying prevention messages. Participants highlighted the need for religious parents to offer both religious and practical guidance to adolescents about sexual health. Findings from this study may be used to inform future sexual health promotion interventions for religious African-American families. PMID:24901449

  3. Family therapy with unmarried African American mothers and their adolescents.

    Science.gov (United States)

    Becker, D; Liddle, H A

    2001-01-01

    Almost two-thirds of African American births are to unmarried mothers, and these single parents are among the most economically vulnerable in the United States. The effects of chronic stressors such as poverty can compromise the ability of these mothers to parent effectively, particularly during the developmental period of adolescence, typically a stressful phase of parenting. This article describes a multidimensional family therapy (MDFT) approach to working with African American adolescents who have drug and/or behavior problems. It is maintained that addressing the intrapersonal functioning of African American single mothers is vital if they are to re-establish the attachment bonds necessary for the maintenance of essential parental influence in the lives of their adolescents. Through systematic attention to the parent as an individual, leading to a balance between self-care and care for others, parental supervision is more easily achieved and relational impasses between parent and adolescent more equitably resolved. PMID:11802488

  4. African American Women’s Perceptions and Experiences about Breastfeeding

    Directory of Open Access Journals (Sweden)

    Cecilia S Obeng

    2015-12-01

    Full Text Available There are health benefits to breastfeeding for both mothers and their children. The preventive health effects of breastfeeding continue into adulthood, lowering rate of various chronic illnesses. African American women, especially of lower socioeconomic status, are less likely to breastfeed in comparison to their racial and ethnic counterparts. The purpose of this study was to explore how African American women experience breastfeeding in the early stages of postpartum care. Two focus groups (N=20, 10 in each group were conducted with African American mothers. Results revealed that participants felt that there were health benefits to breastfeeding, and organizations such as WIC provided support. However, participants stated that lack of information, negative perceptions, and unforeseen circumstances were barriers to breastfeeding. This study proposes support and interventions for this group to increase breastfeeding among this population.

  5. Breast Cancer Risk in American Women

    Science.gov (United States)

    ... of Breast & Gynecologic Cancers Breast Cancer Screening Research Breast Cancer Risk in American Women On This Page What ... risk of developing the disease. Personal history of breast cancer : Women who have had breast cancer are more ...

  6. Hormone-dependent effects of FGFR2 and MAP3K1 in breast cancer susceptibility in a population-based sample of post-menopausal African-American and European-American women

    OpenAIRE

    Timothy R Rebbeck; DeMichele, Angela; Tran, Teo V.; Panossian, Saarene; Bunin, Greta R.; Troxel, Andrea B.; Strom, Brian L

    2008-01-01

    FGFR2 and MAP3K1 are members of the RAS/RAF/MEK/ERK-signaling pathway and have been identified from genome-wide association studies to be breast cancer susceptibility genes. Potential interactions of these genes and their role with respect to tumor markers, hormonal factors and race on breast cancer risk have not been explored. We examined FGFR2 and MAP3K1 variants, breast tumor characteristics and hormone exposures in a population-based case–control sample of 1225 European-American (EA) and ...

  7. Writing Differences in Teacher Performance Assessments: An Investigation of African American Language and Edited American English

    Science.gov (United States)

    Szpara, Michelle Y.; Wylie, E. Caroline

    2008-01-01

    Differential performance results occur when a specific population subgroup achieves a passing rate which is significantly lower than that of the normative reference group. African Americans do less well, in general, on all types of assessments, including constructed-response tests. The present study examined the writing styles of African American…

  8. Psychocultural Correlates of Mental Health Service Utilization Among African American and European American Girls.

    Science.gov (United States)

    Yasui, Miwa; Hipwell, Alison E; Stepp, Stephanie D; Keenan, Kate

    2015-11-01

    Structural equation modeling was used to examine the effects of cultural factors (ethnic identity, perceived discrimination), family relations, and child problem type on mental health service utilization in a community sample of 1,480 adolescent girls (860 African American, 620 European American) between ages 15 and 17 years enrolled in the Pittsburgh Girls Study. Results revealed ethnic identity, caregiver attachment, and conduct disorder were related to service use among African American girls. Among European American girls, correlate patterns differed by clinical need. Findings highlight the need for research on health disparities to examine racially specific influences on service utilization. PMID:25380787

  9. Recruiting African Americans into Research on Cognitive Aging

    OpenAIRE

    McDougall, Graham J.; Holston, Ezra C.; Wilke, Pat

    2001-01-01

    A total of 218 adults with an average age of seventy-eight years participated in a study of memory performance in community elders. A computer-generated random zip code list of adults ≥70 years of age was purchased and a four-phase telephone-screening plan was adopted. During the second year, the sampling plan had to be changed, with a convenience-sampling plan being adopted to recruit adequate numbers of African-American subjects. Fifty-seven percent of the African-American subjects (N = 55)...

  10. The Decline in African-American Representation in Unions and Auto Manufacturing, 1979-2004

    OpenAIRE

    John Schmitt; Ben Zipperer

    2006-01-01

    This report examines the unionization rates of African-American workers and finds that the relative representation of African Americans has been steadily declining in unions, manufacturing, and auto manufacturing.

  11. What Factors Influence Consumption of Food Away From Home by African-Americans?

    OpenAIRE

    Tegegne, Fissesha; Ekanem, Enefiok; Singh, Surendra P.; Speller-Henderson, Leslie

    2009-01-01

    This paper documents consumption of Food Away From Home (FAFH) by selected African­ Americans residing in Nashville, Tennessee, and identifies factors that influence the decision of African-Americans to consume FAFH.

  12. Cognitive Skill, Skill Demands of Jobs, and Earnings among Young European American, African American, and Mexican American Workers.

    Science.gov (United States)

    Farkas, George; And Others

    1997-01-01

    Analyses of National Longitudinal Survey data indicate that cognitive skill level affects access to high-skill occupations and earnings. Lower cognitive skill levels for African Americans and U.S.-born Mexican Americans explain a substantial proportion of income differences between these groups and European Americans but not the gender gap in pay…

  13. African Americans and Network Disadvantage: Enhancing Social Capital through Participation on Social Networking Sites

    OpenAIRE

    Danielle Taana Smith

    2013-01-01

    This study examines the participation of African Americans on social networking sites (SNS), and evaluates the degree to which African Americans engage in activities in the online environment to mitigate social capital deficits. Prior literature suggests that compared with whites, African Americans have less social capital that can enhance their socio-economic mobility. As such, my research question is: do African Americans enhance their social capital through their participation on SNS? I us...

  14. HIV Risk Behaviors among African American Women with at-Risk Male Partners

    OpenAIRE

    Paxton, KC; Williams, JK; Bolden, S; Guzman, Y; Harawa, NT

    2013-01-01

    Background: HIV continues to impact African American women at alarming rates. Yet, few researchers have examined the relationship factors promoting unprotected sex within African American communities, especially instances in which women are aware that their male partners are engaging in high risk behaviors. This qualitative study explored the sexual behaviors, relationship characteristics, and HIV prevention strategies utilized by African American women in relationships with African American ...

  15. African-American mitochondrial DNAs often match mtDNAs found in multiple African ethnic groups

    Directory of Open Access Journals (Sweden)

    Jackson Fatimah

    2006-10-01

    Full Text Available Abstract Background Mitochondrial DNA (mtDNA haplotypes have become popular tools for tracing maternal ancestry, and several companies offer this service to the general public. Numerous studies have demonstrated that human mtDNA haplotypes can be used with confidence to identify the continent where the haplotype originated. Ideally, mtDNA haplotypes could also be used to identify a particular country or ethnic group from which the maternal ancestor emanated. However, the geographic distribution of mtDNA haplotypes is greatly influenced by the movement of both individuals and population groups. Consequently, common mtDNA haplotypes are shared among multiple ethnic groups. We have studied the distribution of mtDNA haplotypes among West African ethnic groups to determine how often mtDNA haplotypes can be used to reconnect Americans of African descent to a country or ethnic group of a maternal African ancestor. The nucleotide sequence of the mtDNA hypervariable segment I (HVS-I usually provides sufficient information to assign a particular mtDNA to the proper haplogroup, and it contains most of the variation that is available to distinguish a particular mtDNA haplotype from closely related haplotypes. In this study, samples of general African-American and specific Gullah/Geechee HVS-I haplotypes were compared with two databases of HVS-I haplotypes from sub-Saharan Africa, and the incidence of perfect matches recorded for each sample. Results When two independent African-American samples were analyzed, more than half of the sampled HVS-I mtDNA haplotypes exactly matched common haplotypes that were shared among multiple African ethnic groups. Another 40% did not match any sequence in the database, and fewer than 10% were an exact match to a sequence from a single African ethnic group. Differences in the regional distribution of haplotypes were observed in the African database, and the African-American haplotypes were more likely to match haplotypes

  16. Knowledge, beliefs, and risk factors for osteoporosis among African-American and Hispanic women.

    Science.gov (United States)

    Geller, S E; Derman, R

    2001-01-01

    The purpose of this work was to develop and conduct a needs and risk instrument to assess knowledge of osteoporosis risk factors, identify beliefs and attitudes about this disease, and delineate the presence and/or absence of healthy behaviors associated with osteoporosis among African American and Hispanic women. The survey findings suggest that African-American and Hispanic women are not well-versed in behaviors that would promote and maintain optimal bone mass. Consequently, they are not practicing appropriate lifestyle and dietary habits to decrease their risk of osteoporosis. Such behaviors include inadequate physical activity, inadequate calcium intake, cigarette smoking, and long-term steroid use. Less than 10% of women in the study were getting adequate daily dietary calcium intake, with only 13% taking daily calcium supplements to augment this deficit and less than one-half of women exercising at a minimal level (20 minutes/3 times a week). Women in this study also had limited knowledge about osteoporosis, perceived this condition to be less of a health threat as compared to breast cancer, heart disease, diabetes, and Alzheimer's disease, and very few had the perception that being Hispanic or African American was a factor to consider in assessing their risk of osteoporosis. Our findings suggest that osteoporosis education and prevention initiatives are needed, specifically for African-American and Hispanic women, to promote healthy behaviors, identify women at-risk, and encourage early diagnosis and treatment. PMID:12653376

  17. Comparative study of matrix metalloproteinase expression between African American and Caucasian Women

    OpenAIRE

    Lashley Kerrie; Jett Marty; Mason Jacquline; Yancy Haile; Day Agnes

    2004-01-01

    Abstract To date there are 26 human matrix metalloproteinases (MMPs) which are classified according to their substrate specificity and structural similarities. The four major subgroups of MMPs are gelatinases, interstitial collagenases, stromelysins, and membrane-type matrix metalloproteinases (MT-MMPs). This study investigates the expression of 26 MMPs, which have been shown to play a role in cancer metastasis. Breast tissues and cell lines derived from African American patients and Caucasia...

  18. Comparative study of matrix metalloproteinase expression between African American and Caucasian Women

    OpenAIRE

    Mason, Jacquline A; Yancy, Haile F; Lashley, Kerrie; Jett, Marty; Day, Agnes A

    2004-01-01

    To date there are 26 human matrix metalloproteinases (MMPs) which are classified according to their substrate specificity and structural similarities. The four major subgroups of MMPs are gelatinases, interstitial collagenases, stromelysins, and membrane-type matrix metalloproteinases (MT-MMPs). This study investigates the expression of 26 MMPs, which have been shown to play a role in cancer metastasis. Breast tissues and cell lines derived from African American patients and Caucasian patient...

  19. Missing Voices: African American School Psychologists' Perspectives on Increasing Professional Diversity

    Science.gov (United States)

    Proctor, Sherrie L.; Truscott, Stephen D.

    2013-01-01

    Since the mid 1960s, there has been a noticeable decrease in the percentage of African American educators. Although a sizeable literature is dedicated to understanding how to recruit African American teachers, fewer studies focus on recruiting and retaining African American school psychologists. Therefore, this exploratory qualitative study…

  20. Mentoring and Professional Identity Development for African American Female Doctoral Students: An Exploratory Study

    Science.gov (United States)

    Curry, Nettavia Doreen

    2011-01-01

    This dissertation examines the impact mentoring relationships, between African American women doctoral students and faculty members, has on the students' professional identity development. Of particular interest is an examination of whether matched mentoring relationships between African American women doctoral students and African American female…

  1. Race, Class, Gender and Community College Persistence among African American Women

    Science.gov (United States)

    Walpole, MaryBeth; Chambers, Crystal Renee; Goss, Kathryn

    2014-01-01

    This inquiry is an exploration of the educational trajectories of African American women community college students. We compare the persistence of African American women to African American men and to all women college students using the 1996/2001 Beginning Postsecondary Students Longitudinal Survey and the 1993/2003 Baccalaureate and Beyond…

  2. "Brother Where Art Thou?" African American Male Instructors' Perceptions of the Counselor Education Profession

    Science.gov (United States)

    Brooks, Michael; Steen, Sam

    2010-01-01

    The purpose of this study was to investigate the perceptions of African American male counselor educators regarding the limited number of African American male faculty members in counselor education. Implications and suggestions on how universities can recruit and retain African American male faculty members are provided.

  3. Comparison of Role Perceptions of White and African American Foster Parents

    Science.gov (United States)

    Nasuti, John P.; York, Reginald; Sandell, Karen

    2004-01-01

    The number of U.S. children entering foster care is increasing faster than the number of available foster parents. Of particular concern are the growing number of African American children in foster care and the lack of African American foster parents to care for them. This study compares role perceptions of African American and white foster…

  4. Orienting African American Male Adolescents toward Meaningful Literacy Exchanges with Texts

    Science.gov (United States)

    Tatum, Alfred W.

    2014-01-01

    Drawing from a sociohistorical understanding of the roles of texts for African American males and data from a recent survey of teens' meaningful experiences with texts, the author provides a general understanding of the roles of texts among African American males and African American male adolescents' meaningful relationships with texts. These…

  5. Nuances of Error: Considerations Relevant to African American Vernacular English and Learning to Read

    Science.gov (United States)

    Compton-Lilly, Catherine

    2005-01-01

    This paper explores the presence of African American Vernacular English patterns in the reading of one child over a 20-week period. In this paper, I present insights from linguists about African American Vernacular English, list linguistic patterns characteristic of African American Vernacular English speakers, examine the relationship between the…

  6. Examining the Writing of Adolescent African American English Speakers: Suggestions for Assessment and Intervention

    Science.gov (United States)

    Horton-Ikard, RaMonda; Pittman, Ramona T.

    2010-01-01

    This article describes the use of African American English (AAE) in the written and oral language of African American adolescents who struggle with writing. Written and oral language samples of 22 African American 10th-grade students were transcribed, analyzed, and coded for AAE, grammatical errors, spelling errors, and punctuation errors. Four…

  7. Lifting the Voices of High-Achieving, Middle-Class, African American Students

    Science.gov (United States)

    Brown, Stacey Marvetta

    2012-01-01

    The state of African American education is complex. Beginning in the 17th century, African Americans fought for an education that allowed them to read and write. During the 21st century, African Americans value on education extends beyond only reading and writing to using these skills and other skills to maintain strong academic and leadership…

  8. African American Faculty Expressing Concerns: Breaking the Silence at Predominantly White Research Oriented Universities

    Science.gov (United States)

    Ross, Henry H.; Edwards, Willie J.

    2016-01-01

    A Delphi method was used with a panel of 24 African American faculty employed at 43 predominantly white doctoral extensive universities to arrive at a group consensus on a list of concerns that African American faculty in general experienced or held. Using the Delphi method a panel of African American faculty initially worked from a list of eight…

  9. A genome-wide association study of breast cancer in women of African ancestry

    OpenAIRE

    Chen, Fang; Chen, Gary K.; Stram, Daniel O.; Millikan, Robert C.; Ambrosone, Christine B.; John, Esther M; Bernstein, Leslie; Zheng, Wei; Palmer, Julie R.; Jennifer J Hu; Rebbeck, Tim R.; Ziegler, Regina G.; Nyante, Sarah; Bandera, Elisa V.; Sue A Ingles

    2012-01-01

    Genome-wide association studies (GWAS) in diverse populations are needed to reveal variants that are more common and/or limited to defined populations. We conducted a GWAS of breast cancer in women of African ancestry, with genotyping of > 1,000,000 SNPs in 3,153 African American cases and 2,831 controls, and replication testing of the top 66 associations in an additional 3,607 breast cancer cases and 11,330 controls of African ancestry. Two of the 66 SNPs replicated (p < 0.05) in stage 2, wh...

  10. African American Women Leaders in Academic Research Libraries

    Science.gov (United States)

    Epps, Sharon K.

    2008-01-01

    Effective leadership and increasing diversity are central concerns in the library profession. Using qualitative interviewing and research methods, this study identifies the attributes, knowledge, and skills that African American women need in order to be successful leaders in today's Association of Research Libraries (ARL). These findings indicate…

  11. HIV among African American Gay and Bisexual Men

    Science.gov (United States)

    ... VIH En Español Get Tested Find an HIV testing site near you. Enter ZIP code or city Follow HIV/AIDS CDC HIV CDC HIV/AIDS See RSS | ... Email Updates on HIV Syndicated Content Website Feedback HIV Among African American Gay and Bisexual Men Format: ...

  12. Culturally Responsive Collegiate Mathematics Education: Implications for African American Students

    Science.gov (United States)

    Jett, Christopher C.

    2013-01-01

    In this article, the author utilizes the culturally congruent work of Gay (2010) and Ladson-Billings (2009) to highlight culturally responsive teaching as a viable option for African American students in higher education mathematics spaces. He offers translations of Gay and Ladson-Billings' work to Africana mathematics and argues that these…

  13. A Motivational Intervention for African American Boys Labeled as Aggressive

    Science.gov (United States)

    Graham, Sandra; Taylor, April; Hudley, Cynthia

    2015-01-01

    A 12-week, 32-lesson afterschool intervention was conducted with third-to fifth-grade urban African American boys classified as aggressive. Grounded in attribution theory and organized around the construct of perceived responsibility in self and others, the intervention focused on increasing both social skills and academic motivation. Participants…

  14. Gender Role Orientation and Anxiety Symptoms among African American Adolescents

    Science.gov (United States)

    Palapattu, Anuradha G.; Kingery, Julie Newman; Ginsburg, Golda S.

    2006-01-01

    The present study evaluated gender role theory as an explanation for the observed gender differences in anxiety symptoms among adolescents. Specifically, the relation between gender, gender role orientation (i.e., masculinity and femininity), self-esteem, and anxiety symptoms was examined in a community sample of 114 African Americans aged 14 to…

  15. Environmental Attitudes and Information Sources among African American College Students

    Science.gov (United States)

    Lee, E. Bun

    2008-01-01

    The author examined the environmental attitudes of African American college students by using the 15-item New Ecological Paradigm (NEP) Scale. The author also attempted to determine their everyday environmental behaviors such as recycling and conservation and investigated major information sources for local, national, and international…

  16. African American Homeschooling and the Quest for a Quality Education

    Science.gov (United States)

    Mazama, Ama; Lundy, Garvey

    2015-01-01

    Academic interest in homeschooling has increased over the last decade, as what was once perceived as a marginal development, has, in fact, turned into a significant and growing phenomenon. There has been, in recent years, a noticeable surge in African American involvement in the homeschooling movement as well. However, there continues to be a…

  17. Albert Sidney Beckham: The First African American School Psychologist

    Science.gov (United States)

    Graves, Scott L., Jr.

    2009-01-01

    Albert Sidney Beckham was the first African American to hold the title school psychologist. This article examines the life and professional career of Beckham in the context of his contributions to the field of school psychology. It explores his graduate education, the founding of Howard University's Psychological Laboratory and his research and…

  18. Early Academic Experiences of Recently Incarcerated African American Males

    Science.gov (United States)

    Jeffers, Adam R.

    2010-01-01

    This project examines the early educational experiences of 6 young African American males (ages 18-25) who attended urban schools in San Diego, California. All 6 men were incarcerated for at least 1-year before participating in a pre-release program. The participants were part of a pre-release program in San Diego, California, which was selected…

  19. Cultural Identification and Academic Achievement among African American Males

    Science.gov (United States)

    Irving, Miles Anthony; Hudley, Cynthia

    2008-01-01

    This study investigated the relationship between intercultural perceptions, identity, and academic achievement among African American males. Specifically, this study investigated the relationship of academic achievement, cultural mistrust, oppositional cultural attitudes, ethnic identity development and educational outcome expectations and value,…

  20. African American Male Student-Athletes: Identity and Academic Performance

    Science.gov (United States)

    O'Brien, Kathryn Mary

    2012-01-01

    The purpose of the current research was to examine racial, male and athletic identities and their individual and collective impact on the academic performance of African American male Division I student-athletes (AAMSAs). Data was collected using the Multidimensional Inventory of Black Identity (MIBI), the Male Role Norms Scale (MRNS), and the…

  1. Constructing Academic Inadequacy: African American Athletes' Stories of Schooling.

    Science.gov (United States)

    Benson, Kirsten F.

    2000-01-01

    This qualitative study interviewed eight academically "at risk" African American athletes at a southeastern university with a major revenue-producing football program. Analysis suggested that the athletes' marginal academic performance was constructed in a system of interrelated practices engaged in by all the significant members of the academic…

  2. African American adolescents' academic persistence: a strengths-based approach.

    Science.gov (United States)

    Butler-Barnes, Sheretta T; Chavous, Tabbye M; Hurd, Noelle; Varner, Fatima

    2013-09-01

    African American adolescents are faced with the challenge to be successful academically, even though they may experience racial discrimination within school settings. Unfortunately, relatively little scholarship explores how African American adolescents draw on personal and cultural assets to persist and thrive in the face of discriminatory experiences. Additionally, little research has explored the buffering role of assets (e.g., racial pride, self-efficacy, and self-acceptance) on the relationship between school-based racial discriminatory experiences and the academic persistence of African American adolescents. Participants in the current study included 220 (58 % girls) socioeconomically diverse African American adolescents. Latent class analysis was utilized to identify clusters based on participants' racial pride, self-efficacy, and self-acceptance. Three cluster groups were identified. The majority of the students belonged to the average group in which adolescents reported average levels of the three study assets. Adolescents in the higher group reported higher assets relative to their peers in the study and those in the lower group reported lower strength-based assets relative to their peers. Results indicated that school-based racial discrimination was associated with lower levels of academic persistence. Additionally, adolescents in the higher assets group reported higher academic persistence in comparison to the average and low group. Our model reflected a promotive but not protective influence of adolescents' assets on their academic persistence. PMID:23700259

  3. African American Women's Sexual Objectification Experiences: A Qualitative Study

    Science.gov (United States)

    Watson, Laurel B.; Robinson, Dawn; Dispenza, Franco; Nazari, Negar

    2012-01-01

    The purpose of our study was to investigate African American women's experiences with sexual objectification. Utilizing grounded theory methodology as well as Black feminist thought and objectification theory as the research lenses, the results of this study uncovered how racist, sexist, and classist ideologies contributed to sexual…

  4. 76 FR 32851 - African-American Music Appreciation Month, 2011

    Science.gov (United States)

    2011-06-07

    .... (Presidential Sig.) [FR Doc. 2011-14170 Filed 6-6-11; 8:45 am] Billing code 3195-W1-P ...#0;#0; #0; #0;Title 3-- #0;The President ] Proclamation 8684 of May 31, 2011 African-American Music Appreciation Month, 2011 By the President of the United States of America A Proclamation The music of...

  5. Eating Disorders in African American Girls: Implications for Counselors

    Science.gov (United States)

    Talleyrand, Regine M.

    2010-01-01

    Given the recent focus on eating disorders in children, it is imperative that counselors consider eating concerns that affect children of all racial and ethnic groups and hence are effective in working with this population. The author discusses risk factors that potentially contribute to eating disorders in African American girls given their…

  6. Young African American Boys Narrating Identities in Science

    Science.gov (United States)

    Kane, Justine M.

    2016-01-01

    The goal of this study is to bring the voices of African American boys front and center in science education research in an effort to strengthen our understandings of their experiences of school and science. Using an interpretivist perspective within a narrative inquiry approach, I focus on the student and science-student identities two African…

  7. African American Students with Disabilities: Beneficiaries of the Legacy?

    Science.gov (United States)

    Boone, Rosalie S.; King-Berry, Arlene

    2007-01-01

    Impressive advancements have been made in educational opportunities for students with disabilities, whose historic relationship with American public schools has been marked by educational disenfranchisement or mis-education. Critical judicial impetus for these educational opportunities was provided by landmark court cases in which African American…

  8. The Origins of African-American Family Structure.

    Science.gov (United States)

    Ruggles, Steven

    1994-01-01

    Uses the Integrated Public Use Microdata Series to trace race differences in African American family structure between 1880 and 1980. Confirms a long-standing high incidence rate of single parenthood and children residing without their parents. Data also show blacks have had a consistently higher percentage of extended households than have whites.…

  9. Alternatives to Suspending African American High School Males

    Directory of Open Access Journals (Sweden)

    Peter P. KIRIAKIDIS

    2014-12-01

    Full Text Available The research site was one high school in the southern United States where African American males were suspended at greater rates than their counterparts. The purpose of this qualitative case study was to examine the perspectives of high school administrators and teachers regarding alternatives to suspending African American males in one southern high school within a public school district. Guided by the social learning theory, the research question focused on the suspensions of these students. Data were collected through in-depth, semi structured, face-to-face interviews with a purposive sample of 6 high school teachers and 2 administrators, and coded and analyzed for emergent themes. The findings revealed that African American high school males might benefit from education programs such as character education programs to develop social, academic, and discipline skills. The findings of this study may be used for professional development for teachers and administrators regarding strategies to reduce suspensions of African American high school males, which might facilitate their graduation from high school and subsequent entry into higher education or the workforce.lications to display the level of psychological strain and workplace stressors among nurses as part of the postmodern organizational problems. Classification-JEL: A23

  10. Gender and Homework Management Reported by African American Students

    Science.gov (United States)

    Xu, Jianzhong

    2010-01-01

    The present study linked gender and grade level to homework management strategies and homework completion behaviours. The participants were 685 African American students in the south-eastern USA, including 370 eighth graders and 315 eleventh graders. Gender appeared related to the majority of homework measures examined in the present study.…

  11. Why African American College Students Miss the Perfect Test Score

    Science.gov (United States)

    Gentry, Ruben; Stokes, Dorothy

    2016-01-01

    Many African Americans were imbued with the cliché that they must work twice as hard as others to be a success in life. Entering college, students with this belief put extensive effort into earning top grades to ensure quality preparation for their chosen career; yet, some fail to earn top scores. Why? This is the million dollar question, but the…

  12. Leadership Development and the African American Male College Student Experience

    Science.gov (United States)

    Oaks, D'Arcy John; Duckett, Kirstan; Suddeth, Todd; Kennedy-Phillips, Lance

    2013-01-01

    Qualitative interviews were employed to assess the effectiveness of a leadership program geared toward African American male personal and professional development, and to examine the relationship between program participation and connectedness. Elements of both social engagement (mentoring and being mentored, peer-to-peer relationships, and…

  13. Behavioural Precursors and HIV Testing Behaviour among African American Women

    Science.gov (United States)

    Uhrig, Jennifer D.; Davis, Kevin C.; Rupert, Doug; Fraze, Jami

    2012-01-01

    Objective: To examine whether there is an association between knowledge, attitudes and beliefs, reported intentions to get an HIV test, and reported HIV testing behaviour at a later date among a sample of African American women. Design: Secondary analysis of data collected from October 2007 through March 2008 for a randomized controlled experiment…

  14. Reasons for African American Student Attrition from School Psychology Programs

    Science.gov (United States)

    Proctor, Sherrie L.; Truscott, Stephen D.

    2012-01-01

    This phenomenological study used a series of three in-depth interviews with seven African American participants, for a total of 21 interviews, to explore their experiences in the specialist and doctoral level school psychology programs they left prior to obtaining a professional entry-level degree. The study's purpose was to investigate what…

  15. Neighborhood Matters: Racial Socialization of African American Children

    Science.gov (United States)

    Caughy, Margaret O'Brien; Nettles, Saundra Murray; O'Campo, Patricia J.; Lohrfink, Kimberly Fraleigh

    2006-01-01

    Differences in racial socialization practices and their effects were examined in a sample of 241 African American 1st graders (average age 6.59 years) living in an urban area. Child outcomes included cognitive development, receptive language skills, and child problem behavior. The cultural environment of the home was associated with higher…

  16. What Are the Real Risk Factors for African American Children?

    Science.gov (United States)

    Jackson, Jacquelyne Faye

    1999-01-01

    Educators should banish the specter of African-American children as high-risk, budding disasters and closely examine these children's schooling environment. Black children of all incomes are schooled in highly segregated settings, due to residential segregation. Exposure to health hazards (lead-based paint) and corporal punishment are serious…

  17. African American College Students: Literacy of Depression and Help Seeking

    Science.gov (United States)

    Stansbury, Kim L.; Wimsatt, Maureen; Simpson, Gaynell Marie; Martin, Fayetta; Nelson, Nancy

    2011-01-01

    Depression is a serious public health concern in the United States affecting almost 18.8 million adults. It is a common mental disorder in college students, with estimates of 1 in 4 "experiencing an episode by age 24." African American college students are at an elevated risk for depression due to racism, stress, sleep deprivation, and lack of…

  18. Contextual Stress and Health Risk Behaviors among African American Adolescents

    Science.gov (United States)

    Copeland-Linder, Nikeea; Lambert, Sharon F.; Chen, Yi-Fu; Ialongo, Nicholas S.

    2011-01-01

    This study examined the longitudinal association between contextual stress and health risk behaviors and the role of protective factors in a community epidemiologically-defined sample of urban African American adolescents (N = 500; 46.4% female). Structural equation modeling was used to create a latent variable measuring contextual stress…

  19. Dismantling the Wall: A White Professor and African American Students.

    Science.gov (United States)

    Koger, Alicia Kae

    1995-01-01

    A white woman professor teaching a black theater history course describes her experiences in the classroom, including the realization of students' expectations of her, her own fears of miscommunicating, the perspectives expressed by students in their journals, differences in white and African American student responses to the same material, and…

  20. The Role of Religiosity in African American Preadolescent Aggression

    Science.gov (United States)

    Holmes, Khiela J.; Lochman, John E.

    2012-01-01

    This study examined the role of parent and preadolescent religiosity in aggression among African American preadolescents with moderate to high aggression. Hierarchical regression analyses were used to determine (a) which aspects of parent and preadolescent religiosity (i.e., church attendance, private religious activities, and intrinsic…

  1. Biculturalism and Academic Achievement of African American High School Students

    Science.gov (United States)

    Rust, Jonathan P.; Jackson, Margo A.; Ponterotto, Joseph G.; Blumberg, Fran C.

    2011-01-01

    Biculturalism was examined as a factor that may positively affect the academic achievement of African American high school students, beyond cultural identity and self-esteem. Hierarchical regression analyses determined that cultural identity and academic self-esteem were important factors for academic achievement, but not biculturalism.…

  2. Substance Abuse: Implications for Counseling African American Men.

    Science.gov (United States)

    Wade, Jay C.

    1994-01-01

    Examines factors--such as unemployment, economic deprivation, racism, issues pertaining to gender roles--and their contribution to substance abuse in African American men. Specifically reviews the use of alcohol, opiates, crack, and cocaine. Argues that a biopsychosocial model offers the best framework in conceptualizing substance abuse and…

  3. Child Maltreatment and Delinquency Onset among African American Adolescent Males

    Science.gov (United States)

    Williams, James Herbert; Van Dorn, Richard A.; Bright, Charlotte Lyn; Jonson-Reid, Melissa; Nebbitt, Von E.

    2010-01-01

    Child welfare and criminology research have increasingly sought to better understand factors that increase the likelihood that abused and neglected children will become involved in the juvenile justice system. However, few studies have addressed this relationship among African American male adolescents. The current study examines the relationship…

  4. African American Accounting Majors and the 150-hr Requirement

    Science.gov (United States)

    Booker, Quinton; Hill, Cecil L.; Wright, Carl

    2010-01-01

    The study provides information on African American accounting majors' views regarding 150-hr issues. The authors collected data from 152 students at two schools. Students at one school supported the requirement while those at the other school did not. However, students believed that the 150-hr requirement enhances the quality of certified public…

  5. Fostering Healthy Lifestyles in the African American Population

    Science.gov (United States)

    Murimi, Mary; Chrisman, Matthew S.; McAllister, Tiffany; McDonald, Olevia D.

    2015-01-01

    Approximately 8.3% of the U.S. population (25.8 million people) is affected by type 2 diabetes. The burden of diabetes is disproportionately greater in the African American community. Compared with non-Hispanic Caucasian adults, the risk of diagnosed type 2 diabetes was 77% higher among non-Hispanic Blacks, who are 27% more likely to die of…

  6. Diary of an African-American Freshman at Harvard College.

    Science.gov (United States)

    Millner, Caille

    1998-01-01

    An African-American freshman at Harvard University keeps a diary of her first year at college, noting experiences of racial isolation and solidarity, and the difficulties in being both Black and female in the highly competitive Harvard environment. A recurring theme is that of her alienation from others. (SLD)

  7. African American Women and Eating Disturbances: A Meta-Analysis.

    Science.gov (United States)

    O'Neill, Shannon K.

    2003-01-01

    Data from 18 studies were reviewed to investigate the relationship between ethnicity and eating disturbances, focusing on the relationship between African American and white women. Although white women had more risk of eating disturbances, the effect size was small. White women had slightly more risk for all eating disturbances combined. African…

  8. The Sociocultural Benefits of Writing for African American Adolescent Males

    Science.gov (United States)

    Tatum, Alfred; Gue, Valerie

    2012-01-01

    Historically speaking, reading and writing among African Americans were collaborative acts involving a wide range of texts that held social, economic, political, or spiritual significance. One of the constants of literacy collaboratives was being regularly and purposefully engaged with print within a meaningful social context. During the summer of…

  9. Vitamin D supplementation in young White and African American women.

    Science.gov (United States)

    Gallagher, J Christopher; Jindal, Prachi S; Smith, Lynette M

    2014-01-01

    There is limited information on the effects of vitamin D on serum 25 hydroxyvitamin D (25OHD) in young people and none on African Americans. The main objective of this trial was to measure the effect of different doses of vitamin D3 on serum 25OHD and serum parathyroid hormone (PTH) in young women with vitamin D insufficiency (serum 25OHD ≤ 20 ng/mL (50 nmol/L). A randomized double-blind placebo-controlled trial of vitamin D3 was conducted in young white and African American women, age 25 to 45 years. A total of 198 healthy white (60%) and African American (40%) women were randomly assigned to placebo, or to 400, 800, 1600, or 2400 IU of vitamin D3 daily. Calcium supplements were added to maintain a total calcium intake of 1000 to 1200 mg daily. The primary outcomes of the study were the final serum 25OHD and PTH levels at 12 months. The absolute increase in serum 25OHD with 400, 800, 1600, and 2400 IU of vitamin D daily was slightly greater in African American women than in white women. On the highest dose of 2400 IU/d, the mixed model predicted that mean 25OHD increased from baseline 12.4 ng/mL (95% confidence interval [CI], 9.2-15.7) to 43.2 ng/mL (95% CI, 38.2-48.1) in African American women and from 15.0 ng/mL (95% CI, 12.3-17.6) to 39.1 ng/mL (95% CI, 36.2-42.0) in white women. There was no significant effect of vitamin D dose on serum PTH in either race but there was a significant inverse relationship between final serum PTH and serum 25OHD. Serum 25OHD exceeded 20 ng/mL in 97.5% of whites on the 400 IU/d dose and between 800 and 1600 IU/d for African Americans. The recommended dietary allowance (RDA) suggested by the Institute of Medicine for young people is 600 IU daily. The increase in serum 25OHD after vitamin D supplementation was similar in young and old, and in white and African American women. PMID:23761326

  10. African American and European American Students' Peer Groups during Early Adolescence: Structure, Status, and Academic Achievement

    Science.gov (United States)

    Wilson, Travis; Karimpour, Ramin; Rodkin, Philip C.

    2011-01-01

    Focusing on a sample of 382 African American (206 female) and 264 European American (132 female) students in diverse fourth and fifth grade classrooms, this study investigated three questions concerning the connections between peer groups and academic achievement during early adolescence: (a) How is group structure (i.e., hierarchy and cohesion)…

  11. Relational Variables and Life Satisfaction in African American and Asian American College Women

    Science.gov (United States)

    Berkel, LaVerne A.; Constantine, Madonna G.

    2005-01-01

    The authors explored associations among relationship harmony, perceived family conflicts, relational self-concept, and life satisfaction in a sample of 169 African American and Asian American college women. As hypothesized, higher relational self-concept, or the extent to which individuals include close relationships in their self-concepts, and…

  12. Dialect Awareness and Lexical Comprehension of Mainstream American English in African American English-Speaking Children

    Science.gov (United States)

    Edwards, Jan; Gross, Megan; Chen, Jianshen; MacDonald, Maryellen C.; Kaplan, David; Brown, Megan; Seidenberg, Mark S.

    2014-01-01

    Purpose: This study was designed to examine the relationships among minority dialect use, language ability, and young African American English (AAE)-speaking children's understanding and awareness of Mainstream American English (MAE). Method: Eighty-three 4- to 8-year-old AAE-speaking children participated in 2 experimental tasks. One task…

  13. Kill Them Before They Grow. Misdiagnosis of African American Boys in American Classrooms.

    Science.gov (United States)

    Porter, Michael

    This book contends that the American public education system has made "black male" synonymous with "disabled" through the creation of the labels "Behavior Disorders" and "Emotional Disorders." These labels, which say that African American boys cannot behave without special treatment, juvenile probation, and, in many cases, drugs, condemns African…

  14. Parenting within Cultural Context: Comparisons between African-American and Asian-American Parents

    Science.gov (United States)

    Wu, Fang; Qi, Sen

    2005-01-01

    Using the sub-samples drawn from the National Early Childhood Longitudinal Study: Kindergarten (ECLS-K) database, this study examines similarities and differences between African-American and Asian-American parents in their parenting practice (i.e., parental involvement at home, expectations of child, emotional expressiveness, school involvement,…

  15. Parenting and Perceived Maternal Warmth in European American and African American Adolescents

    Science.gov (United States)

    Jackson-Newsom, Julia; Buchanan, Christy M.; McDonald, Richard M.

    2008-01-01

    Traditional conceptualizations of parenting style assume certain associations between parenting practices/philosophies and parental warmth. This study examines whether those links are similar for European American and African American adolescents. Two hundred and ninety-eight early adolescents and their mothers reported on discipline and control…

  16. Successful African American women in science: A narrative inquiry

    Science.gov (United States)

    Petty, Cailisha L.

    This study used narrative inquiry as a methodology to explore the lived experiences of five African American women in science across the academic spectrum, from doctoral candidate to full professor. The research questions guiding the inquiry included one overarching question and three sub-questions: What are the lifestories of successful African American women in science?; a) How do successful African American women in science define themselves?; b) What have been the facilitators and barriers encountered by successful African American women in science?; and c) What have been the systems of support for African American women in science? The study was theoretically positioned within the frameworks of Critical Race Theory and Black Feminist Thought. The two theories were used to guide all aspects of the study including methodology, data collection, and analysis. Data included eleven 40-60 minute semi-structured interview transcripts as well as the participants' Curriculum Vitae. The study design and data analysis were built upon Clandinin and Connelly's (2000) and Clandinin's (2006) model of narrative inquiry which explores narratives as a means to understand experience. Analysis and interpretation created three dominant narratives: Scientific Beginnings, An Unexpected Journey, and Lift as You Climb. Each narrative set explores multiple stories that describe storylines which aligned with the participants' goals of who they were and who they were becoming as scientists; and, storylines of tension which ran counter to the women's goals and aspirations. Barriers and support systems are revealed, as well as the meanings the participants made of their experiences and how it affected their lives.

  17. Multiple loci associated with renal function in African Americans.

    Directory of Open Access Journals (Sweden)

    Daniel Shriner

    Full Text Available The incidence of chronic kidney disease varies by ethnic group in the USA, with African Americans displaying a two-fold higher rate than European Americans. One of the two defining variables underlying staging of chronic kidney disease is the glomerular filtration rate. Meta-analysis in individuals of European ancestry has identified 23 genetic loci associated with the estimated glomerular filtration rate (eGFR. We conducted a follow-up study of these 23 genetic loci using a population-based sample of 1,018 unrelated admixed African Americans. We included in our follow-up study two variants in APOL1 associated with end-stage kidney disease discovered by admixture mapping in admixed African Americans. To address confounding due to admixture, we estimated local ancestry at each marker and global ancestry. We performed regression analysis stratified by local ancestry and combined the resulting regression estimates across ancestry strata using an inverse variance-weighted fixed effects model. We found that 11 of the 24 loci were significantly associated with eGFR in our sample. The effect size estimates were not significantly different between the subgroups of individuals with two copies of African ancestry vs. two copies of European ancestry for any of the 11 loci. In contrast, allele frequencies were significantly different at 10 of the 11 loci. Collectively, the 11 loci, including four secondary signals revealed by conditional analyses, explained 14.2% of the phenotypic variance in eGFR, in contrast to the 1.4% explained by the 24 loci in individuals of European ancestry. Our findings provide insight into the genetic basis of variation in renal function among admixed African Americans.

  18. Associations of cigarette smoking with rheumatoid arthritis in African Americans

    Science.gov (United States)

    Mikuls, Ted R.; Sayles, Harlan; Yu, Fang; LeVan, Tricia; Gould, Karen A.; Thiele, Geoffrey M.; Conn, Doyt; Jonas, Beth L.; Callahan, Leigh F.; Smith, Edwin; Brasington, Richard; Moreland, Larry W.; Reynolds, Richard; Bridges, S. Louis

    2010-01-01

    Objective To examine the associations of cigarette smoking with rheumatoid arthritis (RA) in African Americans and to determine to whether this association is impacted by HLA-DRB1 shared epitope (SE). Methods Smoking status, cumulative smoking exposure, and SE status were measured in African American patients with RA and in healthy controls. Associations of smoking with RA were examined using age- and gender-adjusted logistic regression. Additive and multiplicative SE-smoking interactions were examined. Results After adjusting for age and gender, ever (OR = 1.45; 95% CI 1.07 to 1.97) and current smoking (OR = 1.56; 95% CI 1.07 to 2.26) were more common in African American RA cases (n = 605) than in controls (n = 255). The association of smoking with RA was limited to those with a cumulative exposure exceeding 10 pack-years, associations that were evident in both autoantibody positive and negative disease. There was evidence of a significant additive interaction between SE status and heavy smoking (≥ 10 pack-years) in RA risk (attributable proportion due to interaction [AP] of 0.58, p = 0.007) with an AP of 0.47 (p = 0.006) between SE status and ever smoking. There was no evidence of multiplicative interactions. Conclusion Among African Americans, cigarette smoking is associated not only with the risk of autoantibody positive RA but also with the risk of autoantibody negative disease. RA risk attributable to smoking is limited to African Americans with more than 10 pack-years of exposure and is more pronounced among individuals positive for HLA-DRB1 SE. PMID:20722010

  19. Culturally sensitive instructional practices for African-American learners with disabilities.

    Science.gov (United States)

    Franklin, M E

    1992-01-01

    This article discusses the cultural and educational needs of African-American learners with disabilities. Six theoretical assumptions establish some basic suppositions about culturally and linguistically diverse learners and effective instructional practices. A review of the literature describes African-American cultural practices, interests, and cognitive styles; highlights the attitudes, perceptions, and instructional practices of effective teachers of African-American students; and includes patterns of teacher-student and peer-group interactions that promote high academic achievement among African-American learners. Recommendations include organizing teaching, learning, and performance in ways that are compatible with the social structure of African-American students with disabilities. PMID:1425853

  20. Asian American and African American masculinities : race, citizenship, and culture in post-civil rights

    OpenAIRE

    Chon-Smith, Chong

    2006-01-01

    Through the interpretation of labor department documents, journalism, and state discourses, I historicize the formation of both the construction of black "pathology" and the Asian "model minority" by analyzing the comparative racialization of African Americans and Asian Americans in the United States. Beginning with the Moynihan Report and journalistic reports about Asian Americans as "model minority," Black and Asian men were racialized together, as if "racially magnetized," in an attempt to...

  1. Physical Activities and Sedentary Pursuits in African American and Caucasian Girls

    Science.gov (United States)

    Dowda, Marsha; Pate, Russell R.; Felton, Gwen M.; Saunders, Ruth; Ward, Dianne S.; Dishman, Rod K.; Trost, Stewart G.

    2004-01-01

    The purposes of this study were to describe and compare the specific physical activity choices and sedentary pursuits of African American and Caucasian American girls. Participants were 1,124 African American and 1,068 Caucasian American eighth-grade students from 31 middle schools. The 3-Day Physical Activity Recall (3DPAR) was used to measure…

  2. Risk Factors of Sexual Harassment by Peers: A Longitudinal Investigation of African American and European American Adolescents

    Science.gov (United States)

    Goldstein, Sara E.; Malanchuk, Oksana; Davis-Kean, Pamela E.; Eccles, Jacquelynne S.

    2007-01-01

    The present research explores risk factors for, and longitudinal associations of, sexual harassment by peers during adolescence. Eight-hundred and seventy-two African American and European American adolescents (65.4% African American, 51.1% females) were assessed during the summer after the eighth grade (mean age=14.2 years) and then again in the…

  3. Proteomic-coupled-network analysis of T877A-androgen receptor interactomes can predict clinical prostate cancer outcomes between White (non-Hispanic and African-American groups.

    Directory of Open Access Journals (Sweden)

    Naif Zaman

    Full Text Available The androgen receptor (AR remains an important contributor to the neoplastic evolution of prostate cancer (CaP. CaP progression is linked to several somatic AR mutational changes that endow upon the AR dramatic gain-of-function properties. One of the most common somatic mutations identified is Thr877-to-Ala (T877A, located in the ligand-binding domain, that results in a receptor capable of promiscuous binding and activation by a variety of steroid hormones and ligands including estrogens, progestins, glucocorticoids, and several anti-androgens. In an attempt to further define somatic mutated AR gain-of-function properties, as a consequence of its promiscuous ligand binding, we undertook a proteomic/network analysis approach to characterize the protein interactome of the mutant T877A-AR in LNCaP cells under eight different ligand-specific treatments (dihydrotestosterone, mibolerone, R1881, testosterone, estradiol, progesterone, dexamethasone, and cyproterone acetate. In extending the analysis of our multi-ligand complexes of the mutant T877A-AR we observed significant enrichment of specific complexes between normal and primary prostatic tumors, which were furthermore correlated with known clinical outcomes. Further analysis of certain mutant T877A-AR complexes showed specific population preferences distinguishing primary prostatic disease between white (non-Hispanic vs. African-American males. Moreover, these cancer-related AR-protein complexes demonstrated predictive survival outcomes specific to CaP, and not for breast, lung, lymphoma or medulloblastoma cancers. Our study, by coupling data generated by our proteomics to network analysis of clinical samples, has helped to define real and novel biological pathways in complicated gain-of-function AR complex systems.

  4. Do Birds of a Feather Flock Together? The Variable Bases for African American, Asian American, and European American Adolescents' Selection of Similar Friends.

    Science.gov (United States)

    Hamm, Jill V.

    2000-01-01

    Examined variability in adolescent-friend similarity in African American, Asian American, and European American adolescents. Found greatest similarity for substance use, modest for academic orientation, and low for ethnic identity. Found that compared with other groups, African Americans chose friends who were less similar in academic orientation…

  5. What African Americans with Diabetes or High Blood Pressure Need to Know: Get Checked for Kidney Disease

    Science.gov (United States)

    ... m our online catalog. Alternate Language URL What African Americans with Diabetes or High Blood Pressure Need to ... is the #1 cause of kidney failure among African Americans. High blood pressure is the #2 cause. African ...

  6. They Lift My Spirit Up: Stakeholders' Perspectives on Support Teams for African Americans Facing Serious Illness

    Science.gov (United States)

    Jackson, LeRon C.; Hanson, Laura C.; Hayes, Michelle; Green, Melissa; Peacock, Stacie; Corbie-Smith, Giselle

    2014-01-01

    Background: Active social and spiritual support for persons with cancer and other serious illnesses has been shown to improve psychological adjustment to illness and quality of life. Objective: To evaluate a community-based support team intervention within the African American community using stakeholder interviews. Methods: Support team members…

  7. Racial Discrimination, John Henryism, and Depression Among African Americans

    Science.gov (United States)

    Hudson, Darrell L.; Neighbors, Harold W.; Geronimus, Arline T.; Jackson, James S.

    2016-01-01

    Evidence from previous studies indicates that racial discrimination is significantly associated with depression and that African Americans with higher levels of socioeconomic status (SES) report greater exposure to racial discrimination compared to those with lower SES levels. Coping strategies could alter the relationship between racial discrimination and depression among African Americans. This study first examined whether greater levels of SES were associated with increased reports of racial discrimination and ratings of John Henryism, a measure of high-effort coping, among African Americans. Second, we examined whether high-effort coping moderated the relationship between racial discrimination and depression. Data were drawn from the National Survey of American Life Reinterview (n = 2,137). Analyses indicated that greater levels of education were positively associated with racial discrimination (p < .001) and increased levels of racial discrimination were positively related to depression (p < .001), controlling for all sociodemographic factors. Greater levels of John Henryism were associated with increased odds of depression but there was no evidence to suggest that the relationship between discrimination and depression was altered by the effects of John Henryism. PMID:16259481

  8. Birthweight, parental age, birth order and breast cancer risk in African-American and white women: a population-based case–control study

    OpenAIRE

    Hodgson, M Elizabeth; Newman, Beth; Millikan, Robert C.

    2004-01-01

    Introduction Much recent work has focused on hypotheses that very early life exposures influence adult cancer risk. For breast cancer it has been hypothesized that high in utero estrogen exposure may increase risk. Methods We used data from the Carolina Breast Cancer Study, a population-based case–control study of incident breast cancer in North Carolina, to examine associations for three possible surrogates of high prenatal estrogen exposure: weight at birth, maternal age, and birth order. W...

  9. Impact of College Environments on the Spiritual Development of African American Students

    Science.gov (United States)

    Weddle-West, Karen; Hagan, Waldon Joseph; Norwood, Kristie M.

    2013-01-01

    This study focused on the impact of college environments on the spiritual development of African American students. Using the Armstrong Measure of Spirituality (AMOS) survey administered to 125 African American college students, the study sought to ascertain whether or not there were differences in spirituality as reported by African American…

  10. Pragmatic Features in Original Narratives Written by African American Students at Three Grade Levels

    Science.gov (United States)

    Kersting, Jessica M.; Anderson, Michele A.; Newkirk-Turner, Brandi L.; Nelson, Nickola W.

    2015-01-01

    African American English has a rich oral tradition, with identifiable features across all 5 systems of language--phonology, morphology, syntax, semantics, and pragmatics. This is an investigation of the extent to which pragmatic features of African American oral storytelling traditions are apparent in the written stories of African American…

  11. Neighborhood Racial Composition, Racial Discrimination, and Depressive Symptoms in African Americans

    OpenAIRE

    English, Devin; Lambert, Sharon F.; Evans, Michele K.; Zonderman, Alan B

    2014-01-01

    While evidence indicates that experienced racial discrimination is associated with increased depressive symptoms for African Americans, there is little research investigating predictors of experienced racial discrimination. This paper examines neighborhood racial composition and sociodemographic factors as antecedents to experienced racial discrimination and resultant levels of depressive symptoms among African American adults. The sample included 505 socioeconomically-diverse African America...

  12. Digital expression among urban, low-income African American adolescents.

    Science.gov (United States)

    Baker, Christina M; Staiano, Amanda E; Calvert, Sandra L

    2011-01-01

    Digital production is a means through which African American adolescents communicate and express their experiences with peers. This study examined the content and the form of the digital productions of 24 urban, low-income African American adolescents who attended a summer academic program. The content of student digital productions focused on academic experiences and friendships. Their production styles revealed that youth used perceptually salient production features, such as rapid scene changes and loud rap music. The results suggest that when placed in a supportive, academic environment and provided with digital production resources, students who traditionally face barriers due to cultural and economic inequalities digitally express to their peers an interest in academics and positive peer relationships, and that these youth communicate their experiences through a shared production style that reflects their broader cultural experiences. PMID:21910270

  13. Home Literacy Environment of African American Head Start Children

    Directory of Open Access Journals (Sweden)

    Janese Daniels

    2012-08-01

    Full Text Available Researchers have documented culturally specific family literacy practices in which low-income families engage, which are often a function of the context in which the family is currently embedded.  These practices are well documented in ethnographic literature. Although this evidence exists, its utility is limited due to small sample sizes and lack of quantitative documentation on their contribution to children’s language and literacy development.  This study attempted to quantify those culturally specific family literacy practices.  51 low-income African-American mother-child dyads participated.  The contribution of multiple literacy practices was examined in relation to child language and literacy outcomes.  Most low-income African-American families engaged in multiple literacy practices.  Recommended areas for future research directions are discussed.

  14. Culturally competent practice with African American juvenile sex offenders.

    Science.gov (United States)

    Venable, Victoria M; Guada, Joseph

    2014-01-01

    African American juveniles adjudicated for sexual offenses may struggle with the mistrust of both the judicial and treatment systems. Unlike general mental health services, juvenile sex offender treatment is often mandated by the court or child welfare services, thus these youths and their families must engage in the treatment process. Without clinicians and services that can acknowledge and respond to a minority youth's experience in a sensitive, culturally competent manner, there could be significant resistance to treatment. Traditional treatment approaches fail to prioritize issues involving cultural competence. This article addresses the unique challenges of African American juvenile sex offenders and makes recommendations for creating culturally competent practice for these youth and their families. PMID:24641684

  15. Experiences and Learning Needs of African American Family Dementia Caregivers.

    Science.gov (United States)

    Samson, Zoe Blake; Parker, Monica; Dye, Clinton; Hepburn, Kenneth

    2016-09-01

    Dementia family caregivers display significant rates of psychological and physical symptoms. African Americans (AAs) are disproportionately affected by dementia. African American caregivers display unique patterns of symptomology and responses to interventions designed to promote caregiver well-being. This study analyzed qualitative focus group data from 32 AA caregivers to explore how issues of race and culture may be incorporated into a culturally sensitive intervention for AA dementia family caregivers. Caregivers were asked scripted questions about their caregiving experiences and to suggest alterations to an existing psychoeducation program. Analysis revealed 4 key themes: the tradition of family care, caregiving and caregiving issues, culturally appropriate care, and navigating without a map. Suggestions for an educational program included a focus on developing caregiver skills and knowledge for caregiving, promotion of self-care, and reflection on the AA family and community as resources for care. PMID:26953236

  16. Correlates of Polyvictimization Among African American Youth: An Exploratory Study.

    Science.gov (United States)

    Elsaesser, Caitlin M; Voisin, Dexter R

    2015-10-01

    African American adolescents are exposed to high rates of community violence, and recent evidence indicates that these youth may also be at high risk of polyvictimization. Guided by an ecological approach, this study explored individual, familial, and extra-familial correlates of single and multiple forms of violence exposures (i.e., witnessing verbal parental aggression, witnessing or being a victim of community violence exposures) among a sample of 563 urban African American adolescents. Findings indicated that boys reported higher levels of polyvictimization than girls. In addition, the correlates of violence exposures varied by typology and gender. These findings support the development and use of gender-oriented approaches for identifying youth at risk of various types of violence exposures. PMID:25392381

  17. Academic Growth Trajectories and Family Relationships among African American Youth

    Science.gov (United States)

    Dotterer, Aryn M.; Lowe, Katie; McHale, Susan M.

    2016-01-01

    This study explored trajectories of African American youths’ academic functioning and assessed whether changes in parent-adolescent relationships were associated with changes in youths’ academic functioning. The data were drawn from a three-year longitudinal study of gender socialization and development in two-parent African American families and included 197 families. Findings revealed gender differences in achievement trajectories and indicated that boys not only had lower levels of academic achievement compared to girls, but also experienced steeper declines in school self-esteem during adolescence. Changes in parent-adolescent relationship quality were linked to changes in academic functioning: Increases in conflict were related to decreases in GPA, school bonding, and school self-esteem and increases in warmth were related to increases in school bonding and school self-esteem. PMID:27122959

  18. Men Do Matter: Ethnographic Insights on the Socially Supportive Role of the African American Uncle in the Lives of Inner-City African American Male Youth

    Science.gov (United States)

    Richardson, Joseph B., Jr.

    2009-01-01

    This article examines the role of the African American uncle as a vital yet overlooked form of social support and social capital in the lives of adolescent African American male sons living in single-female-headed households. Research rarely examines the affective roles and functions of men in Black families; moreover, poor urban Black male youth…

  19. Impegno nero: Italian intellectuals and the African-American struggle

    OpenAIRE

    Leavitt, Charles L.

    2013-01-01

    In the aftermath of the Second World War, Italian intellectuals participated in Italy’s reconstruction with an ideological commitment inspired by the African-American struggle for equal rights in the United States. Drawing on the work of many of the leading figures in postwar Italian culture, including Italo Calvino, Giorgio Caproni, Cesare Pavese, and Elio Vittorini, this essay argues that Italian intellectual impegno—defined as the effort to remake Italian culture and to guide Italian socia...

  20. Health information-seeking behavior and older African American women.

    OpenAIRE

    Gollop, C J

    1997-01-01

    This study explored the ways in which urban, older, African American women obtain health information and some of the factors that influence such activity. Among the possible determinants examined were self-perceived literacy, access to health information, and mobility. The findings suggest that respondents receive health information from their physicians, the mass media, and members of their social networks. The results of this research also indicated that members of this population have a hi...

  1. Excessive Drinking Among African American Men: Individual and Contextual Correlates

    OpenAIRE

    DePadilla, Lara; Elifson, Kirk; McCarty, Frances; Sterk, Claire

    2012-01-01

    In this paper we explored associations of multiple domains with regular drinking and getting drunk among adult African American men. Questionnaire-based, computer-assisted interviews were conducted with 484 men in Atlanta, Georgia. Data analysis involved multivariate logistic regression analyses. Findings show that being older increased the odds of both drinking behaviors. Sensation seeking increased the odds of regular drinking and having experienced childhood sexual and physical abuse incre...

  2. Developmental Origins of Perfectionism Among African American Youth

    OpenAIRE

    Herman, Keith C.; Trotter, Reid; Reinke, Wendy M.; Ialongo, Nicholas

    2011-01-01

    The present study used a person-centered latent variable approach to classify types of perfectionism among 6th-grade African American children living in an urban setting. In particular, the authors were interested in determining whether an adaptive subtype could be found and validated against external criteria. The authors also attempted to identify any developmental precursors that could reliably differentiate the perfectionist subtypes. A social learning and competence framework was used to...

  3. Social and Environmental Risk Factors for Hypertension in African Americans

    OpenAIRE

    Rahman, Selina; Hu, Howard; McNeely, Eileen; Rahman, Saleh M. M.; Krieger, Nancy; Waterman, Pamela; Peters, Junenette; Harris, Cynthia; Harris, Cynthia H.; Prothrow-Stith, Deborah; Gibbs, Brian K.; Brown, Perry C.; Johnson, Genita; Burgess, Angela; Gragg, Richard D

    2008-01-01

    This study tests the hypothesis that disparities of hypertension risk in African Americans is related to lead exposure, perceptions of racism, and stress, among urban (Roxbury, MA) and rural (Gadsden, FL) communities. Analysis of preliminary data from Phase I reveal 60% in Gadsden and 39% in Roxbury respondents self-reported having hypertension. In Gadsden 80% people did not know if their residence contained lead paint, compared to 45% in Roxbury. In Gadsden County, 58% of respondents reporte...

  4. African American Women, Hair Care, and Health Barriers

    OpenAIRE

    Gathers, Raechele Cochran; Mahan, Meredith Grace

    2014-01-01

    Objectives: The objective of this study was to elucidate the prevalence of hair loss among African American women; explore the psychosocial impact of hair grooming difficulties; and examine both perceptions related to physician encounters in this group and the relationship between hair grooming, physical activity, and weight maintenance. Design: An anonymous retrospective and qualitative survey, the Hair Care Assessment Survey, is an 18-question novel survey instrument designed at the Henry F...

  5. Substance Use Correlates of Depression among African American Male Inmates

    OpenAIRE

    Holliday, Rhonda Conerly; Braithwaite, Ronald L.; Yancey, Elleen; Akintobi, Tabia; Stevens-Watkins, Danielle; Smith, Selina; Powell, C. Lamonte

    2016-01-01

    Substance use correlates of depressive symptoms among incarcerated adult male African American substance users were examined in the current study. Frequency of drug use was assessed with 12 items specific to an individual’s substance use. The Patient Depression Questionnaire (PHQ-9) was used to assess symptoms of depression. Approximately 90% of the sample displayed symptoms of depression ranging from minimal to severe. Regression models revealed that three substance use variables demonstrate...

  6. Expanding the Obesity Research Paradigm to Reach African American Communities

    Directory of Open Access Journals (Sweden)

    Shiriki K. Kumanyika, PhD, MPH

    2007-10-01

    Full Text Available Obesity is more prevalent among African Americans and other racial and ethnic minority populations than among whites. The behaviors that determine weight status are embedded in the core social and cultural processes and environments of day-to-day life in these populations. Therefore, identifying effective, sustainable solutions to obesity requires an ecological model that is inclusive of relevant contextual variables. Race and ethnicity are potent stratification variables in U.S. society and strongly influence life contexts, including many aspects that relate to eating and physical activity behaviors. This article describes a synthesis initiated by the African American Collaborative Obesity Research Network (AACORN to build and broaden the obesity research paradigm. The focus is on African Americans, but the expanded paradigm has broader implications and may apply to other populations of color. The synthesis involves both community and researcher perspectives, drawing on and integrating insights from an expanded set of knowledge domains to promote a deeper understanding of relevant contexts. To augment the traditional, biomedical focus on energy balance, the expanded paradigm includes insights from family sociology, literature, philosophy, transcultural psychology, marketing, economics, and studies of the built environment. We also emphasize the need for more attention to tensions that may affect African American or other researchers who identify or are identified as members of the communities they study. This expanded paradigm, for which development is ongoing, poses new challenges for researchers who focus on obesity and obesity-related health disparities but also promises discovery of new directions that can lead to new solutions.

  7. Child Maltreatment and Delinquency Onset Among African American Adolescent Males

    OpenAIRE

    Williams, James Herbert; Van Dorn, Richard A.; Bright, Charlotte Lyn; Jonson-Reid, Melissa; Nebbitt, Von E.

    2009-01-01

    Child welfare and criminology research have increasingly sought to better understand factors that increase the likelihood that abused and neglected children will become involved in the juvenile justice system. However, few studies have addressed this relationship among African American male adolescents. The current study examines the relationship between child maltreatment (i.e., neglect, physical abuse, sexual abuse, and other/mixed abuse) and the likelihood of a delinquency petition using a...

  8. Promoting Physical Activity Among Overweight Young African American Women

    Centers for Disease Control (CDC) Podcasts

    2014-01-15

    This podcast is an interview with Nefertiti Durant, MD, MPH, from the University of Alabama at Birmingham about promoting physical activity among overweight and obese young African American Women using Internet-based tools.  Created: 1/15/2014 by Preventing Chronic Disease (PCD), National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 1/15/2014.

  9. Lactose intolerance and health disparities among African Americans and Hispanic Americans: an updated consensus statement.

    Science.gov (United States)

    Bailey, Rahn K; Fileti, Cecelia Pozo; Keith, Jeanette; Tropez-Sims, Susanne; Price, Winston; Allison-Ottey, Sharon Denise

    2013-01-01

    Dairy foods contribute nine essential nutrients to the diet including calcium, potassium and vitamin D; nutrients identified by the 2010 Dietary Guidelines for Americans as being "of public health concern" within the U.S. population. Milk and milk product intake is associated with better diet quality and has been associated with a reduced risk of chronic diseases or conditions including hypertension, cardiovascular disease, metabolic syndrome, Type 2 Diabetes and osteoporosis. Some research also indicates dairy food intake may be linked to reduced body fat, when accompanied by energy-restriction. On average, both African Americans and Hispanic Americans consume less than the recommended levels of dairy foods, and perceived or actual lactose intolerance can be a primary reason for limiting or avoiding dairy intake. True lactose intolerance prevalence is not known because healthcare providers do not routinely measure for it, and no standardized assessment method exists. Avoiding dairy may lead to shortfalls of essential nutrients and increased susceptibility to chronic disease. This updated Consensus Statement aims to provide the most current information about lactose intolerance and health, with specific relevance to the African American and Hispanic American communities. Topics covered include diagnostic considerations, actual and recommended dairy food intake and levels of consumption of key dairy nutrients among African Americans and Hispanic Americans; prevalence of self-reported lactose intolerance among various racial/ethnic groups; the association between dairy food intake, lactose intolerance and chronic disease; and research-based management recommendations for those with lactose intolerance. PMID:24079212

  10. Epigenetic Markers of Renal Function in African Americans

    Directory of Open Access Journals (Sweden)

    Samantha M. Bomotti

    2013-01-01

    Full Text Available Chronic kidney disease (CKD is an increasing concern in the United States due to its rapidly rising prevalence, particularly among African Americans. Epigenetic DNA methylation markers are becoming important biomarkers of chronic diseases such as CKD. To better understand how these methylation markers play a role in kidney function, we measured 26,428 DNA methylation sites in 972 African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA study. We then evaluated (1 whether epigenetic markers are associated with estimated glomerular filtration rate (eGFR, (2 whether the significantly associated markers are also associated with traditional risk factors and/or novel biomarkers for eGFR, and (3 how much additional variation in eGFR is explained by epigenetic markers beyond established risk factors and biomarkers. The majority of methylation markers most significantly associated with eGFR (24 out of the top 30 appeared to function, at least in part, through pathways related to aging, inflammation, or cholesterol. However, six epigenetic markers were still able to significantly predict eGFR after adjustment for other risk factors. This work shows that epigenetic markers may offer valuable new insight into the complex pathophysiology of CKD in African Americans.

  11. Obesity in African-American Women--The Time Bomb is Ticking: An Urgent Call for Change.

    Science.gov (United States)

    Fowler, Barbara A

    2015-12-01

    The "time bomb is ticking" because there is an obesity crisis associated with higher rates of chronic diseases such as stroke, hypertension, type 2 diabetes, and some forms of cancer in African-American women compared to White women. African-American women incur higher medical costs from hospitalizations, decreased productivity in the work setting, lost wages, the needfor medical benefits and pharmacy-associated costs, and more time away from family than White women. Numerous factors, such as the socio-cultural context of eating, acceptance of a larger weight status, the emotionally liberating effects offood, and preference for highfat and high caloric, sugary-content, and sodium-laden food influences the obesity crisis in African-American women. The interplay of poverty and lower socioeconomic status, residential segregation, health literacy, availability of fast foods and scarce produce in local convenience food marts, physical inactivity, and conflicting messages from social media public service announcements (PSAs) and ads in national magazines affect the obesity crisis in African-American women. There is an urgent call for sustainable, community-driven health policy initiatives that improve access to healthy foods in lower-income, minority communities. Furthermore, African-American women are challenged to modify their health behaviors by preparing healthy meals for themselves and theirfamilies, and by engaging in physical activity. PMID:27045156

  12. African Americans and the Spanish-American War and Philippine Insurrection: Military Participation, Recognition, and Memory, 1898-1904

    OpenAIRE

    Russell, Timothy Dale

    2013-01-01

    The Spanish-American War, which began in 1898, coincided with a virulent campaign of racial violence and legal segregation directed at African Americans throughout the "Jim Crow" South. As the jingoism of the day stirred American nationalism, the question of whether to support the war against Spain was much more complicated to even the most patriotic African Americans as they faced an unceasing assault on their civil rights. Utilizing numerous editorials from the black press, and letters fr...

  13. Evaluation of a Structural Model of Objectification Theory and Eating Disorder Symptomatology among European American and African American Undergraduate Women

    OpenAIRE

    Mitchell, Karen S.; Mazzeo, Suzanne E.

    2009-01-01

    The current study evaluated a structural equation model of objectification theory among European American (n = 408) and African American women (n = 233). Modeling results indicated a particularly strong association between thin-ideal internalization/body monitoring and eating disorder symptoms, with weaker relationships among body dissatisfaction, depression, anxiety, and eating disorder symptoms. The measurement model was not equivalent for European Americans and African Americans; however, ...

  14. Pneumococcal Tricuspid Valve Endocarditis in a Young African American: A Case for Inclusion of African Americans in Pneumococcal Vaccine Criteria

    OpenAIRE

    John J. Murray; Joseph Akamah; Oghenerukevwe Odiete; Olagoke Akinwande

    2010-01-01

    Following the development of penicillin, complications from streptococcus pneumonia such as endocarditis have become rare. However, certain independent risk factors such as cigarette smoking and being of African-American (AA) decent have been associated with a higher incidence of invasive pneumococcal disease, but only cigarette smoking has been targeted by current recommendations from the Advisory Committee on Immunological Practices (ACIPs). We report a case of a young AA smoker, who develo...

  15. The Impact of Negative Stereotypes & Representations of African-Americans in the Media and African-American Incarceration

    OpenAIRE

    Johnson, Tamara Therese

    2012-01-01

    The purpose of this study was to investigate the sociological impact of public polices enacted during slavery in the United States. Another goal was to discover whether the negative stereotypes of African-Americans in film are related to the reinforcement of negative perceptions established during slavery. Finally, a review of the disparate outcomes produced by new discriminatory policies within the criminal justice system details the impact of current policies that disproportionately impac...

  16. Race and Class in America's Elite Preparatory Boarding Schools: African Americans as the "Outsiders Within."

    Science.gov (United States)

    Cookson, Peter W., Jr.; Persell, Caroline Hodges

    1991-01-01

    Examines elements of the African American experience in American prep schools, using data from a survey of 55 schools. African Americans must cope with both racial and class distinctions in these schools, but the majority subsequently gain admission to highly selective colleges. (DM)

  17. Anxiety Psychopathology in African American Adults: Literature Review and Development of an Empirically Informed Sociocultural Model

    Science.gov (United States)

    Hunter, Lora Rose; Schmidt, Norman B.

    2010-01-01

    In this review, the extant literature concerning anxiety psychopathology in African American adults is summarized to develop a testable, explanatory framework with implications for future research. The model was designed to account for purported lower rates of anxiety disorders in African Americans compared to European Americans, along with other…

  18. Digital History: Using the Internet to Enhance African American Studies in the Secondary School

    Science.gov (United States)

    Scheuerell, Scott; Jaeger, Matt

    2015-01-01

    The authors discuss how high school students participated in a unit in which they learned about African American history in a 1:1 computer classroom--in particular, how they were able to use digital history to learn about a variety of African American leaders who are not frequently covered in the traditional American History textbook. In addition,…

  19. The Relationship between Maladaptive Eating Behaviors and Racial Identity among African American Women in College

    Science.gov (United States)

    Flowers, Kelci C.; Levesque, Maurice J.; Fischer, Sarah

    2012-01-01

    Research on eating disorders has shown that European American women suffer from eating disorders and body image dissatisfaction more than African American women. However, recent meta-analyses suggest these differences may be decreasing and that some African American women may be particularly susceptible to body dissatisfaction and eating disorder…

  20. Seasonal Changes in Sleep Duration in African American and African College Students Living In Washington, D.C.

    Directory of Open Access Journals (Sweden)

    Janna Volkov

    2007-01-01

    Full Text Available Duration of nocturnal melatonin secretion, a marker of “biological night” that relates to sleep duration, is longer in winter than in summer in patients with seasonal affective disorder (SAD, but not in healthy controls. In this study of African and African American college students, we hypothesized that students who met criteria for winter SAD or subsyndromal SAD (S-SAD would report sleeping longer in winter than in summer. In addition, based on our previous observation that Africans report more “problems” with change in seasons than African Americans, we expected that the seasonal changes in sleep duration would be greater in African students than in African American students. Based on Seasonal Pattern Assessment Questionnaire (SPAQ responses, African American and African college students in Washington, D.C. (N = 575 were grouped into a winter SAD/S-SAD group or a no winter diagnosis group, and winter and summer sleep length were determined. We conducted a 2 (season × 2 (sex × 2 (ethnicity × 2 (winter diagnosis group ANCOVA on reported sleep duration, controlling for age. Contrary to our hypothesis, we found that African and African American students with winter SAD/S-SAD report sleeping longer in the summer than in the winter. No differences in seasonality of sleep were found between African and African American students. Students with winter SAD or S-SAD may need to sacrifice sleep duration in the winter, when their academic functioning/efficiency may be impaired by syndromal or subsyndromal depression, in order to meet seasonally increased academic demands.

  1. Mentoring African American Expatriates: Providing The Bridge To Success Abroad

    Directory of Open Access Journals (Sweden)

    Daria C. Crawley

    2011-07-01

    Full Text Available Employment predictions continue to forecast increasing racial diversity in the American workforce as firms face global competition and strive to grasp the challenges of a global business landscape.  As American multinational corporations use expatriate assignments; supplemented by flexipatriates and inpatriates to meet customer preferences in the global marketplace, growing racial diversity may generate more expatriates of color.  Global human resource management research has focused on issues such as adjustment and cross-cultural development and recently mentoring as critical factors for expatriate success.  A growing body of mentoring research details the career experiences of employees with diverse backgrounds, yet few studies center on the experiences of the African American expatriate.  This article aims to examine African Americans mentoring opportunities in a global environment, with a focus on understanding the role mentoring plays for this particular population group. This work is intended to contribute to the increasing literature on global mentoring and will help to influence the thinking of multinational corporations’ response to the increasing diversity of their global workforce.

  2. Manganese superoxide dismutase Ala-9Val polymorphism and risk of breast cancer in a population-based case–control study of African Americans and whites

    OpenAIRE

    Millikan, Robert C.; Player, Jon; de Cotret, Allan René; Moorman, Patricia; Pittman, Gary; Vannappagari, Vani; Tse, Chiu-Kit J; Keku, Temitope

    2004-01-01

    Introduction A polymorphism in the manganese superoxide dismutase (MnSOD) gene, Ala-9Val, has been examined in association with breast cancer risk in several epidemiologic studies. Results suggest that the Ala allele increases the risk of breast cancer and modifies the effects of environmental exposures that produce oxidative damage to DNA. Methods We examined the role of the MnSOD Ala-9Val polymorphism in a population-based case–control study of invasive and in situ breast cancer in North Ca...

  3. Barriers to Clinical Trial Participation: Comparing Perceptions and Knowledge of African American and White South Carolinians.

    Science.gov (United States)

    Kim, Sei-Hill; Tanner, Andrea; Friedman, Daniela B; Foster, Caroline; Bergeron, Caroline

    2015-01-01

    Analyzing data from a survey of African American and White residents in South Carolina, this study attempts to understand how to better promote clinical trial participation specifically within the African American population. To explore why participation is lower in the African American population, the authors examined two sets of potential barriers: structural/procedural (limited accessibility, lack of awareness, doctors not discussing clinical trial options, lack of health insurance) and cognitive/psychological (lack of subjective and factual knowledge, misperceptions, distrust, fear, perceived risk). Findings revealed that African Americans were significantly less willing than Whites to participate in a clinical trial. African Americans also had lower subjective and factual knowledge about clinical trials and perceived greater risk involved in participating in a clinical trial. The authors found that lack of subjective knowledge and perceived risk were significant predictors of African Americans' willingness to participate in a clinical trial. Implications of the findings are discussed in detail. PMID:26042496

  4. School and peer influences on the academic outcomes of African American adolescents.

    Science.gov (United States)

    Butler-Barnes, Sheretta T; Estrada-Martinez, Lorena; Colin, Rosa J; Jones, Brittni D

    2015-10-01

    Little scholarship explores how adolescents' beliefs about school and peers influence the academic outcomes of African American boys and girls. The sample included 612 African American boys (N = 307, Mage = 16.84) and girls (N = 305, Mage = 16.79). Latent class analysis (LCA) revealed unique patterns for African American boys and girls. Findings indicate that for African American boys, school attachment was protective, despite having peers who endorsed negative achievement values. Furthermore, socio-economic (SES) status was associated with higher grade point averages (GPA) for African American girls. Overall, these findings underscore the unique role of school, peer, and gendered experiences in lives of African American adolescents. PMID:26277404

  5. UGT1A1 and UGT1A9 functional variants, meat intake, and colon cancer, among Caucasians and African Americans

    OpenAIRE

    Girard, Hugo; Butler, Lesley M.; Villeneuve, Lyne; Millikan, Robert C.; Sinha, Rashmi; Sandler, Robert S.; Guillemette, Chantal

    2008-01-01

    Glucuronidation by the UDP-glucuronosyltransferase enzymes (UGTs) is one of the primary detoxification pathways of dietary heterocyclic amines (HCAs) and polycyclic aromatic hydrocarbons (PAHs). In a population-based case-control study of 537 cases and 866 controls, we investigated whether colon cancer was associated with genetic variations in UGT1A1 and UGT1A9 genes and we determined if those variations modify the association between colon cancer and dietary HCA and PAH exposure. We measured...

  6. Gene by Environment Interaction Linking the Chromosome 15q25 Locus With Cigarette Consumption and Lung Cancer Susceptibility — Are African American Affected Differently?

    OpenAIRE

    Hopkins, R.J.; R. P. Young

    2016-01-01

    The majority of lung cancer cases result from complex interactions between smoking exposure, genetic susceptibility and a person's immune response to chronic inflammation or lung remodelling. Epidemiological studies confirm that susceptibility to developing chronic obstructive pulmonary disease (COPD), especially emphysema, is also closely linked to lung cancer susceptibility. Genetic epidemiology studies have consistently reported associations between the chromosome 15q25 locus with lung can...

  7. Stakeholder Perspectives on Barriers for Healthy Living for Low-Income African American Families

    OpenAIRE

    Jones, Veronnie Faye; Rowland, Michael L.; Young, Linda; Atwood, Katherine; Thompson, Kirsten; Sterrett, Emma; Honaker, Sarah Morsbach; Joel E. Williams; Johnson, Knowlton; Davis, Deborah Winders

    2014-01-01

    Background: Childhood obesity is a growing problem for children in the United States, especially for children from low-income, African American families. Objective: The purpose of this qualitative study was to understand facilitators and barriers to engaging in healthy lifestyles faced by low-income African American children and their families. Methods: This qualitative study used semi-structured focus group interviews with eight African American children clinically identified as overwe...

  8. Early Life Predictors of Adult Depression in a Community Cohort of Urban African Americans

    OpenAIRE

    Green, Kerry M.; Fothergill, Kate E.; Robertson, Judith A.; Zebrak, Katarzyna A.; Banda, Deliya R.; Ensminger, Margaret E.

    2012-01-01

    Depression among African Americans residing in urban communities is a complex, major public health problem; however, few studies identify early life risk factors for depression among urban African American men and women. To better inform prevention programming, this study uses data from the Woodlawn Study, a well-defined community cohort of urban African Americans followed from age 6 to 42 years, to determine depression prevalence through midlife and identify childhood and adolescent risk fac...

  9. Reducing Stereotype Threat in Academically At-Risk African-Americans Students: A Self-

    OpenAIRE

    Simmons, Crystal Marie

    2011-01-01

    AbstractReducing Stereotype Threat in Academically At-Risk African- Americans Students: A Self- Affirmation InterventionbyCrystal Marie SimmonsDoctor of Philosophy in EducationUniversity of California, BerkeleyProfessor Frank C. Worrell, ChairIn this study, I examined the effectiveness of a self-affirmation intervention (Cohen et al., 2006) with a sample of African American high school students who were at risk for academic failure. Participants consisted of 47 African-American students from ...

  10. Media and Cultural Influences in African-American Girls' Eating Disorder Risk

    OpenAIRE

    Jones, Lakaii A.; Cook-Cottone, Catherine

    2013-01-01

    Objective. To investigate media and cultural influences in eating disorder development in African-American adolescent females. Method. Fifty-seven participants were recruited through churches and community organizations to complete a questionnaire. Results. Mainstream sociocultural identification was associated with more eating disorder behavior in African-American females; cultural ethnic identification was not significantly associated with eating disorder behavior in African-American female...

  11. A Qualitative Examination of the Maternal Racial Socialization of African American Preschool Children

    OpenAIRE

    Edwards, Adrienne Laney

    2014-01-01

    The salience of racial socialization among African American families has received considerable attention in the literature; however, few scholars have examined how the process of racial socialization unfolds in families with very young children. This study investigated how African American mothers of preschool-age children approached the process of racial socialization. I interviewed African American mothers who were at least age 18 (N=12) with biological children between the ages of three an...

  12. Effect of Adolescent Obesity on Cardiometabolic Risk in African-Americans and Caucasians

    OpenAIRE

    Hoffman, Robert P.

    2012-01-01

    African-Americans have more hypertension, stroke, and type 2 diabetes than do Caucasians. Endothelial dysfunction and insulin resistance are precursors for each. Since these diseases have origins in pediatrics and are associated with obesity, this study was designed to determine if obesity has different effects on endothelial function, insulin sensitivity, and secretion in African-American and Caucasian adolescents. Thirty-three Caucasian and 25 African-Americans (10–18 years old) were subdiv...

  13. Prevalence and Severity of Symptoms in a Sample of African Americans and White Participants

    OpenAIRE

    Taneja, Indu; So, Suzanna; Stewart, Julian M.; Evans, Meredyth; Jason, Leonard A.

    2015-01-01

    According to the Centers for Disease Control and Prevention (2013), African Americans have a substantially greater prevalence of a range of health conditions when compared to other racial or ethnic groups. Many of these conditions have been attributed to the historical and contemporary social and economic disparities faced by the African American community. While many health conditions occur at a higher rate in African Americans, it is unclear whether there are specific symptom clusters that ...

  14. A Review of Genetics, Arterial Stiffness, and Blood Pressure in African Americans

    OpenAIRE

    Hall, Jennifer L.; Duprez, Daniel A; Barac, Ana; Rich, Stephen S.

    2012-01-01

    The prevalence of hypertension in African Americans in the United States is amongst the highest in the world and increasing. The identification of genes and pathways regulating blood pressure in African Americans has been challenging. An early predictor of hypertension is arterial stiffness. The prevalence of arterial stiffness is significantly higher in African Americans compared to Caucasians. Approximately 20% of the variance in arterial stiffness is estimated to be heritable. Identifying ...

  15. The Concrete Jungle: City Stress and Substance Abuse among Young Adult African American Men

    OpenAIRE

    Seth, Puja; Murray, Colleen C.; Braxton, Nikia D.; DiClemente, Ralph J

    2012-01-01

    Substance use is prevalent among African American men living in urban communities. The impact of substance use on the social, psychological, and physical health of African American men has important public health implications for families, communities, and society. Given the adverse consequences of alcohol and drug abuse within communities of color, this study evaluated the relationship between city stress, alcohol consumption, and drug use among African American men. Eighty heterosexual, Afr...

  16. Assessment of Genotype Imputation Performance Using 1000 Genomes in African American Studies

    OpenAIRE

    Hancock, Dana B.; Levy, Joshua L.; Gaddis, Nathan C.; Bierut, Laura J; Saccone, Nancy L.; Page, Grier P.; Johnson, Eric O.

    2012-01-01

    Genotype imputation, used in genome-wide association studies to expand coverage of single nucleotide polymorphisms (SNPs), has performed poorly in African Americans compared to less admixed populations. Overall, imputation has typically relied on HapMap reference haplotype panels from Africans (YRI), European Americans (CEU), and Asians (CHB/JPT). The 1000 Genomes project offers a wider range of reference populations, such as African Americans (ASW), but their imputation performance has had l...

  17. African-American culture and AIDS prevention. From barrier to ally.

    OpenAIRE

    Bowser, B P

    1992-01-01

    African Americans make up an increasing proportion of persons with the acquired immunodeficiency syndrome (AIDS). I identify and describe cultural elements such as oral traditions, multiple naming, a collective identity, extended families, and sexuality influenced by myth and exaggeration that condition African Americans' reactions to AIDS prevention. I also offer suggestions on how these cultural elements can be used for effective AIDS prevention efforts in African-American communities.

  18. The Four Cs of HIV Prevention with African Americans: Crisis, Condoms, Culture, and Community

    OpenAIRE

    Williams, JK; Wyatt, GE; Wingood, G

    2010-01-01

    HIV/AIDS continues to be a devastating epidemic with African American communities carrying the brunt of the impact. Despite extensive biobehavioral research, current strategies have not resulted in significantly decreasing HIV/AIDS cases among African Americans. The next generation of HIV prevention and risk reduction interventions must move beyond basic sex education and condom use and availability. Successful interventions targeting African Americans must optimize strategies that integrate ...

  19. A Case Study of Middle Class African American Males Taking Advanced Mathematics Classes in High School

    OpenAIRE

    Jones, Zella Higginbotham

    2011-01-01

    African American males in all socioeconomic levels are underperforming in school. Many researchers have conducted studies hoping to find reasons for the underperformance. This study focused on three middle class African American males in a suburban school district. These African American male students took upper level math courses that included Algebra III, Math Analysis, AP Calculus, and AP Statistics. This study modeled the study by E. Wayne Harris. He believed students were influenced...

  20. Protective Factors for Depression among African American Children of Predominantly Low-Income Mothers with Depression

    OpenAIRE

    Boyd, Rhonda C; Waanders, Christine

    2012-01-01

    Maternal depression has a deleterious impact on child psychological outcomes, including depression symptoms. However, there is limited research on the protective factors for these children and even less for African Americans. The purpose of the study is to examine the effects of positive parenting skills on child depression and the potential protective effects of social skills and kinship support among African American children whose mothers are depressed and low-income. African American moth...

  1. Abnormal endothelial function in young African-American females: discordance with blood flow.

    Science.gov (United States)

    Bransford, T. L.; St Vrain, J. A.; Webb, M.

    2001-01-01

    In this pilot study, we sought to compare the vasodilatory and hemodynamic properties of the peripheral vasculature in the forearms of young, healthy African-American females to similarly matched white females. We used high-resolution ultrasound of the brachial artery to evaluate 11 African-American females and 8 white females. When normalized to nitrate-induced dilation, endothelium-dependent dilation was reduced in young African American females compared to white females (0.6 in African American females compared to 1.0 in white females). These results indicate the need for a larger study to examine this phenomenon. PMID:12653397

  2. Global Patterns of Prostate Cancer Incidence, Aggressiveness, and Mortality in Men of African Descent

    Directory of Open Access Journals (Sweden)

    Timothy R. Rebbeck

    2013-01-01

    Full Text Available Prostate cancer (CaP is the leading cancer among men of African descent in the USA, Caribbean, and Sub-Saharan Africa (SSA. The estimated number of CaP deaths in SSA during 2008 was more than five times that among African Americans and is expected to double in Africa by 2030. We summarize publicly available CaP data and collected data from the men of African descent and Carcinoma of the Prostate (MADCaP Consortium and the African Caribbean Cancer Consortium (AC3 to evaluate CaP incidence and mortality in men of African descent worldwide. CaP incidence and mortality are highest in men of African descent in the USA and the Caribbean. Tumor stage and grade were highest in SSA. We report a higher proportion of T1 stage prostate tumors in countries with greater percent gross domestic product spent on health care and physicians per 100,000 persons. We also observed that regions with a higher proportion of advanced tumors reported lower mortality rates. This finding suggests that CaP is underdiagnosed and/or underreported in SSA men. Nonetheless, CaP incidence and mortality represent a significant public health problem in men of African descent around the world.

  3. The Great Recession and health risks in African American youth.

    Science.gov (United States)

    Chen, Edith; Miller, Gregory E; Yu, Tianyi; Brody, Gene H

    2016-03-01

    In the present study, we investigated associations of macro-economic conditions - the Great Recession - with cellular epigenetic aging, allostatic load, and self-reported health, in a group that experiences significant health disparities, African Americans. A sample of 330 African American adolescents in Georgia was followed from pre-recession (2007, M age=16.6) to post-recession (2010, M age=19.3). Economic data were collected in both 2007 and 2010. Three groups were formed to represent economic trajectories across the period of the Great Recession (stable low economic hardship, downward mobility, and stable high economic hardship). At age 19, measures of cellular epigenetic aging (derived from leukocyte DNA methylation profiles, reflecting the disparity between a person's biological and chronological age), allostatic load (composite of blood pressure, C reactive protein, cortisol, epinephrine, norepinephrine, and body mass index), and adolescent self-report of health were obtained. Linear trend analyses documented significant differences across all outcomes. The more time adolescents spent under economic hardship, the higher their epigenetic aging [estimate=1.421, SE=0.466, p=.002] and allostatic load [estimate=1.151, SE=0.375, p=.002] scores, and the worse their self-report of health [estimate=4.957, SE=1.800, p=.006]. Specific group comparisons revealed that adolescents in the downward mobility group had higher levels of allostatic load than adolescents in the stable low hardship group [p<.05]. Overall, these findings suggest that the health profiles of African American youth may in part be shaped by environmental macro-economic societal conditions, and that effects on biological markers can be detected relatively early in life. PMID:26718449

  4. Introduction to Exporting American Dreams: Thurgood Marshall's African Journey

    Directory of Open Access Journals (Sweden)

    Mary L. Dudziak

    2009-02-01

    Full Text Available Thurgood Marshall became a living icon of civil rights when he argued Brown v. Board of Education before the Supreme Court in 1954. Six years later, he was at a crossroads. A rising generation of activists were making sit-ins and demonstrations rather than lawsuits the hallmark of the civil rights movement. What role, he wondered, could he now play? When in 1960 Kenyan independence leaders asked him to help write their constitution, Marshall threw himself into their cause. Here was a new arena in which law might serve as the tool with which to forge a just society. In Exporting American Dreams, Mary Dudziak recounts with poignancy and power the untold story of Marshall's journey to Africa. African Americans were enslaved when the U.S. constitution was written. In Kenya, Marshall could become something that had not existed in his own country: a black man helping to found a nation. He became friends with Kenyan leaders Tom Mboya and Jomo Kenyatta, serving as advisor to the Kenyans, who needed to demonstrate to Great Britain and to the world that they would treat minority races (whites and Asians fairly once Africans took power. He crafted a bill of rights, aiding constitutional negotiations that helped enable peaceful regime change, rather than violent resistance. Marshall's involvement with Kenya's foundation affirmed his faith in law, while also forcing him to understand how the struggle for justice could be compromised by the imperatives of sovereignty. Marshall's beliefs were most sorely tested later in the decade when he became a Supreme Court Justice, even as American cities erupted in flames and civil rights progress stalled. Kenya's first attempt at democracy faltered, but Marshall's African journey remained a cherished memory of a time and a place when all things seemed possible.

  5. Keloids and ultrasound detected fibroids in young African American women.

    Directory of Open Access Journals (Sweden)

    Quaker E Harmon

    Full Text Available OBJECTIVE: Keloids and fibroids share a number of biologic and demographic similarities however there are no published reports of the association between them. The objective of this study was to investigate the association between self-reported keloids and ultrasound detected fibroids in a population of young African American women. STUDY DESIGN: The Study of Environment, Life-style & Fibroids (SELF, is a volunteer cohort of over 1600 African American women aged 23-34 years recruited in Detroit, Michigan. Enrollment occurred between December 2010 and December 2012. Data are available for the first 1196 participants. Participants self-reported a history of raised (hypertrophic scars or scars extending beyond the limits of the original injury (keloid and had an enrollment pelvic ultrasound examination to detect prevalent fibroids. Log linear regression was used to model the association between abnormal scars and prevalent fibroids controlling for possible covariates. Among women with fibroids, associations between particular fibroid characteristics (tumor location, size or number and scarring were assessed using chi-square and Mann Whitney U-tests. RESULTS: Both abnormal scarring (keloids, 9.0%; hypertrophic scars, 28.3% and fibroids (23.3% were common in this cohort. There was no indication [adjusted Risk Ratio (95% Confidence Interval: 0.7 (0.5-1.1] of an association between self-reported keloids and prevalent fibroids. Nor was there any association with hypertrophic scars. Specific characteristics of the prevalent fibroids were not associated with abnormal scarring. CONCLUSION: Despite similarly dysregulated extracellular matrices in keloids and fibroids, these conditions did not tend to co-occur in this young African American population.

  6. Seasonal Changes in Sleep Duration in African American and African College Students Living In Washington, D.C.

    OpenAIRE

    Janna Volkov; Kelly J. Rohan; Yousufi, Samina M.; Minh-Chau Nguyen; Jackson, Michael A.; Thrower, Courtney M.; Stiller, John W.; Teodor T. Postolache

    2007-01-01

    Duration of nocturnal melatonin secretion, a marker of “biological night” that relates to sleep duration, is longer in winter than in summer in patients with seasonal affective disorder (SAD), but not in healthy controls. In this study of African and African American college students, we hypothesized that students who met criteria for winter SAD or subsyndromal SAD (S-SAD) would report sleeping longer in winter than in summer. In addition, based on our previous observation that Africans repor...

  7. Early and mid-adolescence risk factors for later substance abuse by African Americans and European Americans.

    OpenAIRE

    Gil, Andres G.; Vega, William A.; Turner, R. Jay

    2002-01-01

    OBJECTIVE: This study examines the relationship between risk factors experienced during adolescence by African Americans and European Americans and DSM-IV alcohol dependence and marijuana abuse or dependence in early adulthood. METHODS: The authors followed a cohort of adolescents from 1990-91 (grades 6 and 7) to 1998-2000 (ages 19-21), evaluating risk factors during early adolescence as predictors of DSM-IV alcohol dependence and marijuana abuse and dependence. RESULTS: African Americans had...

  8. Young Adult, Rural, African American Stimulant Users: Antecedents and Vulnerabilities

    Science.gov (United States)

    Kramer, Teresa L.; Han, Xiaotong; Booth, Brenda M.

    2009-01-01

    Early initiation of substance use appears to be an alarming trend among rural minorities. This study focuses on 18–21 year old African American stimulant users in the Arkansas Mississippi Delta. Most participants had no high school diploma and were unemployed; 74.5% had already been arrested. Substance use was initiated early, and nearly all of the men and three quarters of the women already met criteria for lifetime abuse or dependence. Only 18% reported they had ever received substance abuse treatment. The results suggest that substance use interventions in rural communities will require multi-faceted strategies addressing economic, educational and healthcare disparities. PMID:20098663

  9. Iron Status of Inner-City African-American Infants

    OpenAIRE

    Lozoff, Betsy; Angelilli, Mary Lu; Zatakia, Jigna; Jacobson, Sandra W.; Calatroni, Agustin; Beard, John

    2007-01-01

    The iron status of African-American infants continues to be subject to debate. We characterized the iron status of 198 9-month-old inner-city infants (94% fed iron-fortified formula) using a comprehensive panel of measures and assessing lead and inflammation markers. The proportion with iron deficiency was calculated based on three approaches (≥ 2 abnormal iron measures with or without anemia for MCV model—NHANES II, ferritin model—NHANES III, or Sweden/Honduras study) and a promising new mea...

  10. Violence exposure and teen dating violence among African American youth.

    Science.gov (United States)

    Black, Beverly M; Chido, Lisa M; Preble, Kathleen M; Weisz, Arlene N; Yoon, Jina S; Delaney-Black, Virginia; Kernsmith, Poco; Lewandowski, Linda

    2015-07-01

    This study examines the relationships between exposure to violence in the community, school, and family with dating violence attitudes and behaviors among 175 urban African American youth. Age, gender, state support and experiences with neglect, school violence, and community violence were the most significant predictors of acceptance of dating violence. Experiences with community violence and age were important predictors of dating violence perpetration and victimization. Findings highlight the importance of planning prevention programs that address variables affecting attitudes and behaviors of high-risk youth who have already been exposed to multiple types of violence. PMID:25287413

  11. Exploring resiliency factors of older African American Katrina survivors.

    Science.gov (United States)

    Thomas, Cecilia L

    2012-01-01

    Through this qualitative study the author explores the resiliency processes demonstrated by older African American Hurricane Katrina survivors who relocated in the aftermath of the storm and were consequently faced with difficult challenges. In-depth interviews were used to assess the multidimensional characteristics of resiliency that enabled these older adults to deal with adversity. These findings highlight distinct processes reflecting resiliency: (a) Trusting in a higher power, and the importance of (b) living in the present, (c) activating resources, (d) creating community, and (e) doing for others. The author concludes this study with suggestions on how these findings may inform social work practice with older adults. PMID:22830937

  12. Adherence discourse among African-American women taking HAART

    OpenAIRE

    A. Sankar; Luborsky, M.; Schuman, P.; Roberts, G.

    2002-01-01

    Low adherence is the single most important challenge to controlling HIV through the use of high acting anti-retrovirals (HAART). Non-adherence poses an immediate threat to individuals who develop resistant forms of the virus as well as a public health threat if those individuals pass on treatment-resistant forms of the virus. To understand the concerns and perceptions that promote or deter adherence to antiretroviral medication by HIV-positive African-American women, we conducted in-depth int...

  13. Promoting the interest of African American teenage girls in science: What can we learn from an exemplary African American science teacher?

    Science.gov (United States)

    McMath, Cynthia Stewart

    This study focused on science teaching that promoted the interest of African American teenage girls in the science classroom of an exemplary African American science teacher. It focused on, observed and examined the planning, teaching and learning strategies used by the science teacher. It also described what the science teacher experienced during her high school years, during college, during her teaching career. The case study approach/method was used for this research to capture the description and examination of the practices of the science teacher. This research described how an African American female science teacher serves as a role model and influence a number of African Americans students, especially girls, who experience careers in science. During the interviews and observations the researcher used a system of record keeping for the study to include note taking, audio taping and pictures. It is evident in the findings that the teacher in this study had qualities of an exemplary teacher according to the research. It is further evident that the teacher served as a role model for her students. The results indicated that the exemplary African America science teacher was motivated by her former African American science teacher that served as a role model. The results in this study implied that the lack of the presence of more exemplary African American science teachers has an impact on the level of interest that African American students have in science. Further, it is implied that there is a great need for more practical research that may lead to closing the gap of missing African American science teachers.

  14. African Americans and Network Disadvantage: Enhancing Social Capital through Participation on Social Networking Sites

    Directory of Open Access Journals (Sweden)

    Danielle Taana Smith

    2013-03-01

    Full Text Available This study examines the participation of African Americans on social networking sites (SNS, and evaluates the degree to which African Americans engage in activities in the online environment to mitigate social capital deficits. Prior literature suggests that compared with whites, African Americans have less social capital that can enhance their socio-economic mobility. As such, my research question is: do African Americans enhance their social capital through their participation on SNS? I use nationally representative data collected from the Pew Internet and American Life Project to explore the research question. The results suggest that the online environment is potentially a space in which African Americans can lessen social capital deficits.

  15. Less drinking, yet more problems: understanding African American drinking and related problems.

    Science.gov (United States)

    Zapolski, Tamika C B; Pedersen, Sarah L; McCarthy, Denis M; Smith, Gregory T

    2014-01-01

    Researchers have found that, compared to European Americans, African Americans report later initiation of drinking, lower rates of use, and lower levels of use across almost all age groups. Nevertheless, African Americans also have higher levels of alcohol problems than European Americans. After reviewing current data regarding these trends, we provide a theory to understand this apparent paradox as well as to understand variability in risk among African Americans. Certain factors appear to operate as both protective factors against heavy use and risk factors for negative consequences from use. For example, African American culture is characterized by norms against heavy alcohol use or intoxication, which protects against heavy use but also provides within-group social disapproval when use does occur. African Americans are more likely to encounter legal problems from drinking than European Americans, even at the same levels of consumption, perhaps thus resulting in reduced consumption but more problems from consumption. There appears to be one particular group of African Americans, low-income African American men, who are at the highest risk for alcoholism and related problems. We theorize that this effect is due to the complex interaction of residential discrimination, racism, age of drinking, and lack of available standard life reinforcers (e.g., stable employment and financial stability). Further empirical research will be needed to test our theories and otherwise move this important field forward. A focus on within-group variation in drinking patterns and problems is necessary. We suggest several new avenues of inquiry. PMID:23477449

  16. Beyond parenting practices: extended kinship support and the academic adjustment of African-American and European-American teens.

    Science.gov (United States)

    Pallock, Linda L; Lamborn, Susie D

    2006-10-01

    This study examined adolescents' perceptions of parenting practices and extended kinship support in relation to academic adjustment for 104 African American and 60 European American 9th and 10th graders (14 and 15 year olds). For African-American teens, parental acceptance was associated with school values, teacher bonding, and work orientation. Higher levels of behavioral control and lower levels of psychological control were associated with a stronger work orientation. After accounting for the demographic variables and the three parenting practices, higher levels of extended kinship support related to stronger school values, higher teacher bonding, and a stronger work orientation. For European-American teens, parental acceptance related to academic adjustment, including stronger school values, higher teacher bonding, and a stronger work orientation. European-American adolescents with stronger extended kinship networks reported higher teacher bonding and a stronger work orientation. Results indicate the importance of extended kinship support for both African-American and European-American adolescents. PMID:16455133

  17. Ending Racial Profiling of African-Americans in the Selective Enforcement of Laws: In Search of Viable Remedies

    Directory of Open Access Journals (Sweden)

    Floyd Weatherspoon

    2004-04-01

    Full Text Available In theory, the American justice system is designed to ensure that each American’s basic constitutional rights are preserved and protected. Most Americans, including African-Americans, believe that the justice system protects the constitutional rights of all Americans. However, the extent of this protection is viewed differently by whites and African-Americans. Indeed, African-Americans feel that their constitutional rights have been marginalized by the very systems in place to protect their rights.

  18. Ending Racial Profiling of African-Americans in the Selective Enforcement of Laws: In Search of Viable Remedies

    OpenAIRE

    Floyd Weatherspoon

    2004-01-01

    In theory, the American justice system is designed to ensure that each American’s basic constitutional rights are preserved and protected. Most Americans, including African-Americans, believe that the justice system protects the constitutional rights of all Americans. However, the extent of this protection is viewed differently by whites and African-Americans. Indeed, African-Americans feel that their constitutional rights have been marginalized by the very systems in place to protect t...

  19. My Iowa Journey: The Life Story of the University of Iowa's First African American Professor. Singular Lives: The Iowa Series in North American Autobiography.

    Science.gov (United States)

    Hubbard, Philip G.

    This autobiography recounts the life story of an African American educator at the University of Iowa from 1965 to 1991, as its first African American professor and then as its first African American administrator. The book recounts his childhood and family relations, his student years at the university and his graduation as an electrical engineer,…

  20. The Ellison\\Baraka debate: the conflict in (African) American music

    OpenAIRE

    Mazman, Alper

    2007-01-01

    65 pages The Ellison/Baraka Debate: The Conflict in (African) AmericanAcknowledgementsI. Introduction: Critical Representations of African AmericanMusic…… 1II. The Songs of Sorrow: The Spirituals in the Process ofAmericanization…… 6III. The People of the Blues: The Snowball Effect of the BluesAesthetic…… 16IV. The Representation of Modern Jazz and the Theory of AfricanAmerican Music…… 381. The conflict of the Old and New Guard: Bebop and the Future ofJazz…… 382. The Signifiyin(g) African A...

  1. Factors Associated with Pregnancy among Incarcerated African American Adolescent Girls.

    Science.gov (United States)

    Gray, Simone C; Holmes, Kristin; Bradford, Denise R

    2016-08-01

    The purpose of this study was to examine the social and behavioral factors associated with pregnancy history among a sample of African American adolescent girls recruited from a short-term juvenile detention center in order to better understand the needs of this vulnerable population. Data were collected from a sample of 188 detained African American, 13-17-year-old girls in Atlanta, Georgia, who participated in a larger HIV prevention study. An audio computer-assisted self-interviewing survey was completed by participants to obtain information on socioecological factors to include individual, parental/familial, sexual risk, psychosocial, and substance use factors. Among the 188 participants, 25.5 % reported a history of pregnancy. A multivariable logistic regression model showed that girls with a history of pregnancy were more likely to live in a household receiving government aid, use hormonal contraceptives at last sex, participate in sex trading, have casual sex partners, have condomless sex in the past 90 days, and have a history of physical abuse. Girls with no history of pregnancy were more likely to have been incarcerated at least twice and to have previously used alcohol. Detention-based interventions and pregnancy prevention programs for this vulnerable population may benefit by addressing factors related to sexual behavior and development, substance use, individual background, and psychosocial health. PMID:27271026

  2. Depressive Symptomatology and College Persistence among African American College Students.

    Science.gov (United States)

    Boyraz, Güler; Horne, Sharon G; Owens, Archandria C; Armstrong, Aisha P

    2016-01-01

    The purpose of this study was to examine the relationship between depressive symptomatology and college outcomes among African American students, as well as to determine whether these relationships were moderated by gender and type of university. Participants included 569 African American first-year students attending two public universities in the Southeast United States: a historically Black college/university (HBCU) and a predominantly White institution (PWI). Using a longitudinal study design, data were collected at three time points. Results indicated that, after adjusting for the effects of the control variables (gender, type of institution, high school GPA, participation in on-campus activities, institutional and goal commitments), depressive symptomatology present in the first semester of college was associated with increased likelihood of dropping out of college before the end of the second year of college. The relationship between these two variables was mediated by first-year cumulative GPA. Results also indicated that the hypothesized relationships did not vary as a function of gender and the university type. PMID:27055080

  3. Unheard and Unseen: How Housing Insecure African American Adolescents Experience the Education System

    Science.gov (United States)

    Ellis, Addie Lucille; Geller, Kathy D.

    2016-01-01

    This narrative study is based on stories told by African American adolescents experiencing homelessness. It offers insights into their lived experiences and describes the challenges faced in negotiating the urban education system. African American youth are disproportionately represented in the adolescent homeless demographic. "Unheard and…

  4. African-American Women Journalists and Their Male Editors: A Tradition of Support.

    Science.gov (United States)

    Streitmatter, Rodger

    1993-01-01

    Suggests that African-American women journalists have not been hampered by the sexist attitudes of men to the same degree that white women journalists have been. Presents six case studies of African-American women journalists (three from the nineteenth century and three from the twentieth) in support of this contention. (SR)

  5. Academic Bullying: A Barrier to Tenure and Promotion for African-American Faculty

    Science.gov (United States)

    Frazier, Kimberly N.

    2011-01-01

    The author discusses the problem of retention of African American faculty due to tenure and promotion issues. The author outlines obstacles that African American face in the workplace while seeking tenure and promotion in academia. A case example is presented that illuminates how these stressors manifest in the academic setting and recommendations…

  6. Engaging African American Fathers in Behavioral Parent Training: To Adapt or Not Adapt

    OpenAIRE

    Kohl, Patricia L.; Seay, Kristen D.

    2015-01-01

    The Positive Parenting Program, Triple P, is an evidence-based parenting program with strong empirical support that increases parenting skills and decreases child behavior problems. Few studies on Triple P include fathers or African American fathers. This study was undertaken to determine if adaptation to Triple P level 4 is necessary to ensure fit with urban African American fathers.

  7. Perceived Fatherhood Roles and Parenting Behaviors among African American Teen Fathers

    Science.gov (United States)

    Paschal, Angelia M.; Lewis-Moss, Rhonda K.; Hsiao, Tracy

    2011-01-01

    Despite the growing body of research on the topic of adolescent parenthood, few studies have examined the perceptions and lived experiences of African American teen fathers. The primary aim of this study was to examine how this group defines and performs the father role. In-depth interviews were conducted with 30 African American fathers aged 14…

  8. The Perpetual Homelessness of College Experiences: Tensions between Home and Campus for African American Women

    Science.gov (United States)

    Winkle-Wagner, Rachelle

    2009-01-01

    There is an ongoing debate about whether African American students need to sever ties with their families to be successful in college. Adding nuance to this debate, this ethnographic study examines African American women's experiences of navigating family relationships in a predominantly White institution. The women described multiple pressures…

  9. Superstar or Scholar? African American Male Youths' Perceptions of Opportunity in a Time of Change

    Science.gov (United States)

    Conchas, Gilberto Q.; Lin, Alex R.; Oseguera, Leticia; Drake, Sean J.

    2015-01-01

    Through a Multiple Marginality Framework, this exploratory case study highlights how African American male youth in an urban high school setting perceive the opportunity structure during the historic election of the first African American President. Youth optimism generated by Obama's election gives students a sense of hope despite the persistent…

  10. Institutional Barriers to Participation in Adult Education among African Americans within Religious Institutions.

    Science.gov (United States)

    Isaac, Paulette; Rowland, Michael

    2002-01-01

    Examined institutional deterrents to participation in adult education among African American Christian church members. Focus group interview data highlighted six categories of deterrents: lack of relevance, programmatic, communication, individual/personal, instructional techniques, and interpersonal. Results suggest that African American Christian…

  11. The Influence of Social Capital Factors on African-American and Hispanic High School Student Achievement

    Science.gov (United States)

    Davis, Jacqueline L.

    2009-01-01

    The underachievement of African American and Hispanic students has been an ongoing problem for schools in the United States. The purpose of this investigation was to add to the existing body of knowledge concerning social capital of African American and Hispanic high school students' academic achievement. Using a nationally representative sample…

  12. African-American College Student Attitudes toward Physics and Their Effect on Achievement

    Science.gov (United States)

    Drake, Carl Timothy

    2009-01-01

    The purpose of this study was to investigate factors affecting the attitudes that African-American college students have towards introductory college physics. The population targeted for this study consisted of African-American males and females enrolled in introductory college physics classes at an urban public historical black college or…

  13. Not Just Pushing and Shoving: School Bullying among African American Adolescents

    Science.gov (United States)

    Fitzpatrick, Kevin M.; Dulin, Akilah J.; Piko, Bettina F.

    2007-01-01

    Background: The primary purpose of this study was to examine the prevalence of bullying among a sample of African American adolescents and the risk factors associated with odds that a student engages in bullying behavior. Methods: Using a self-report school-based survey, 1542 African American adolescents from a single school district (grades 5-12)…

  14. Sisters in the Struggle: African American Female Graduate Students Coping with Racism and Racism-Related

    Science.gov (United States)

    Foster, Kelsie

    2013-01-01

    This study examined if coping was predictive of perceived racism and racism related stress of African American female graduate students. Participants were 217 African American female graduate students attending Predominantly White Institutions (PWIs), Hispanic Serving Institutions (HSIs) and Historically Black Colleges and Universities (HBCUs) and…

  15. Critical Race Theory: A Counternarrative of African American Male Medical Students Attending Predominately White Medical Schools

    Science.gov (United States)

    Morgan, Adrienne L.

    2013-01-01

    The history of African Americans seeking medical education in the United States is rooted in a legacy of racial segregation, cultural constructs, and legal doctrine that differs from other ethnic and racial groups. The disturbing results of this legacy are that while African Americans account for 12.9% of the U.S. population, they only account for…

  16. Mentoring 101: Advancing African-American Women Faculty and Doctoral Student Success in Predominantly White Institutions

    Science.gov (United States)

    Grant, Cosette M.; Ghee, Sarah

    2015-01-01

    This article is purposed with operationalizing the concept of mentoring as a nuanced approach and attempt to thwart the upward trajectories of African-American women in predominantly White institutions (PWIs). We struggled as African-American women to balance and decipher the various facets inherent in our respective roles--professor and doctoral…

  17. Stereotype Threat Effects on African American Children in an Urban Elementary School

    Science.gov (United States)

    Wasserberg, Martin J.

    2014-01-01

    This study investigated whether a diagnostic testing condition leads to stereotype threat effects for African American children (n = 198) at an urban elementary school. Results indicated that presenting a reading test as diagnostic of abilities hindered the performance of African American children aware of racial stereotypes but not of those…

  18. Racial Identity Development and Academic Achievement of Academically Gifted African American Students: Implications for School Counselors

    Science.gov (United States)

    Spencer, Natalie F.; Dowden, Angel Riddick

    2014-01-01

    Gifted African American students are underrepresented and underserved in gifted education. The current article provides an overview of proper identification, racial identity development implications, psycho-social concerns and the importance of family involvement in the development of gifted African American students. A case study is presented to…

  19. The Benefits of a Comprehensive Retention Program for African American Students at a Predominately White University

    Science.gov (United States)

    Johnson, Lakitta

    2013-01-01

    Since the passage of the Civil Rights Act of 1964, the retention of African American students at predominately White colleges and universities continues to be problematic. Although many of these institutions have implemented retention programs for African American students, few have incorporated a comprehensive program that utilizes multi-program…

  20. Exploring the Meaning African American PETE Teacher Candidates Ascribe to Their Aquatic Experiences

    Science.gov (United States)

    Sato, Takahiro; Hodge, Samuel R.

    2012-01-01

    Physical Education Teacher Education (PETE) programs typically require their graduates to learn to swim proficiently. However, the research base is underdeveloped regarding the aquatic experiences of African Americans in PETE programs. The purpose of this study was to explore the meaning African American PETE teacher candidates ascribe to their…

  1. College and Career Readiness for Gifted African American Girls: A Call to School Counselors

    Science.gov (United States)

    Mayes, Renae D.; Hines, Erik M.

    2014-01-01

    Current literature on college and career readiness highlights the role of educators in promoting the success of all students. However, few studies have focused on the specific needs of gifted African American girls. This article discusses the school experiences and career development of gifted African American girls and it provides a culturally…

  2. Addressing the Underrepresentation of African-Americans in Counseling and Psychology Programs

    Science.gov (United States)

    Haizlip, Breyan N.

    2012-01-01

    Over the last two decades, there has been an upward trend in the number of African-American doctoral students completing counseling and psychology programs. However, despite these trends, African-American faculty continue to be significantly underrepresented as counseling educators and psychology faculty. Similarly, counseling education programs…

  3. Welcoming Taye: How His English Teacher Embraced an African American Transfer Student in an Affluent Suburb

    Science.gov (United States)

    Hill, K. Dara

    2014-01-01

    This case study narrative examines the circumstances underlying problems of residency in an affluent Midwest suburb experiencing an unexpected influx of working class African American students. Dilemmas engender a cultural mismatch between teachers and students and discomfort with African-American males. In a controversial climate where students…

  4. Emerging from the Pipeline: African American Students, Socioeconomic Status, and College Experiences and Outcomes

    Science.gov (United States)

    Walpole, MaryBeth

    2008-01-01

    This study focuses on how social class affects the college experiences and outcomes for African American students in 4-year colleges and universities. Using a national, longitudinal data base, the findings indicate that low SES African American students have less contact with faculty, study less, are less involved with student organizations, work…

  5. Testing a Culture-Specific Extension of Objectification Theory regarding African American Women's Body Image

    Science.gov (United States)

    Buchanan, Taneisha S.; Fischer, Ann R.; Tokar, David M.; Yoder, Janice D.

    2008-01-01

    Objectification theory has emphasized objectification in terms of body shape and size. African American women may expect to be evaluated on additional physical attributes such as skin tone. Therefore, we extended previous research on objectification theory by adding separate measures of skin-tone concerns in a survey of 117 African American women.…

  6. The Role of Gender in the Racial and Ethnic Socialization of African American Adolescents

    Science.gov (United States)

    Brown, Tiffany L.; Linver, Miriam R.; Evans, Melanie

    2010-01-01

    Scholars in the field of African American family studies recognize the influence of gender on socialization. However, few studies investigate how gender influences the racial and ethnic socialization of African American youth. To examine the role of gender (both caregiver and adolescent) in socialization practices, data were obtained from 218…

  7. Parental Characteristics, Ecological Factors, and the Academic Achievement of African American Males

    Science.gov (United States)

    Hines, Erik M.; Holcomb-McCoy, Cheryl

    2013-01-01

    Parental characteristics, ecological factors, and the academic achievement of African American male high school students were examined. One hundred fifty-three 11th and 12th grade African American males completed the Parenting Style Index (Steinberg, Lamborn, Darling, Mounts, & Dornbusch, 1994) and a demographic questionnaire. Results…

  8. African American Families on Autism Diagnosis and Treatment: The Influence of Culture

    Science.gov (United States)

    Burkett, Karen; Morris, Edith; Manning-Courtney, Patricia; Anthony, Jean; Shambley-Ebron, Donna

    2015-01-01

    Cultural factors such as health care access and autism spectrum disorder (ASD) symptom interpretations have been proposed as impacting delayed diagnosis and treatment for African American children with ASD. A qualitative study of urban African American families caring for their child with autism was conducted with 24 family members and 28 ASD…

  9. African American Adolescents Living and Coping with Community Violence on Chicago's Southside

    Science.gov (United States)

    Voisin, Dexter R.; Bird, Jason D. P.; Hardestry, Melissa; Shiu, Cheng Shi

    2011-01-01

    This study explores community violence exposures among African American adolescents and whether coping strategies were gendered. In-depth interviews are conducted with a sample of 32 African American high school students. Data are analyzed using a thematic analysis. The primary forms of violence exposures are physical attacks, fighting, and…

  10. African Americans and Mathematics Outcomes on National Assessment of Educational Progress: Parental and Individual Influences

    Science.gov (United States)

    Noble, Richard, III; Morton, Crystal Hill

    2013-01-01

    This study investigated within group differences between African American female and male students who participated in the 2009 National Assessment of Educational Progress mathematics assessment. Using results from participating states, we compare average scale scores of African American students based on home regulatory environment and interest…

  11. African American Males and Literacy Development in Contexts That Are Characteristically Urban

    Science.gov (United States)

    Tatum, Alfred W.; Muhammad, Gholnecsar E.

    2012-01-01

    Advancing the literacy development of African American males in contexts that are characteristically urban has been a challenging task for educators across the P-12 spectrum. Frames that have been traditionally used to improve the reading achievement of African American males have not reversed trends in reading achievement that find many of these…

  12. Partnering with a Higher Power: Academic Engagement, Religiosity, and Spirituality of African American Urban Youth

    Science.gov (United States)

    Holland, Nicole E.

    2016-01-01

    Engagement in and transitions between academic institutions may be enhanced for African American urban youth if we consider the role of religiosity, spirituality, and places of worship. This article presents the manner by which African American university students, who attended public high schools, conveyed the influence of their religious and…

  13. The Design and Implementation of an Education Program for African American Inmates

    Science.gov (United States)

    Nelson, Nancy J.

    2007-01-01

    This article describes an education program initiated by African American prisoners in the Airway Heights Correction Center in Airway Heights, Washington. The purpose of the program was to help the inmates to make productive use of their time while incarcerated and to help lessen the high return rate of African American men to the prison. Although…

  14. Helping Moms, Saving Babies: Faith-Based Partnerships to Reduce Prematurity in the African American Community

    Science.gov (United States)

    Lewis, LaToya L.

    2008-01-01

    The March of Dimes, Texas Chapter, partnered with the faith community to pilot Honey Child[SM], a prenatal education program for African American women. The program is designed to combat prematurity, which is the leading cause of death for African American infants. Honey Child uses a spiritual approach to promote prenatal health through…

  15. African American Students and College Choice: A Consideration of the Role of School Counselors

    Science.gov (United States)

    Muhammad, Crystal Gafford

    2008-01-01

    Misinformation in the African American community regarding college costs, access, and the benefits of a college education abound. Counseling from a trustworthy, supportive school counselor can make a difference in stemming African American talent loss, especially among young Black men. Using the 1988 National Educational Longitudinal Survey, the…

  16. Faith-Based Adult Learning Initiatives for Diabetes Education in the African American Community

    Science.gov (United States)

    Gaillard, Trudy

    2006-01-01

    Historically, religion and spirituality have been major influences in the social, cultural, and political lives of African Americans. Spirituality is deeply embedded into their rich cultural heritage, and it is intertwined into all aspects of their life, including beliefs about health and illness. For African Americans, health and illness are a…

  17. Parental Influence, School Readiness and Early Academic Achievement of African American Boys

    Science.gov (United States)

    Joe, Emanique M.; Davis, James Earl

    2009-01-01

    This study examined the relationship between parental influence and the school readiness of African American boys, using data from the Early Childhood Longitudinal Study: ECLS-K, Parents' influence, via their academic beliefs and behaviors, was associated with the cognitive performance of African American boys during kindergarten. While previous…

  18. African American Administrators at PWIs: Enablers of and Barriers to Career Success

    Science.gov (United States)

    Gardner, Levester, Jr.; Barrett, T. Gregory; Pearson, L. Carolyn

    2014-01-01

    Despite literature emphasizing the importance of their presence on college campuses to minority student success, African American administrators are severely underrepresented in higher education. The purpose of this qualitative study was to explore the lived experiences of successful African American student affairs administrators at predominantly…

  19. Understanding the Disproportionately Low Marriage Rate among African Americans: An Amalgam of Sociological and Psychological Constraints

    Science.gov (United States)

    Chambers, Anthony L.; Kravitz, Aliza

    2011-01-01

    African Americans have the lowest marriage rate of any racial and ethnic group in America. Although the low marriage rate among African Americans has been largely examined through a sociological lens by documenting structural barriers, which has important policy implications, researchers have not sufficiently examined the psychological and…

  20. Hypertensive chronic kidney disease in African Americans: Strategies for improving care

    OpenAIRE

    Martins, David; Agodoa, Lawrence; Norris, Keith C.

    2012-01-01

    African Americans have a disproportionate burden of chronic kidney disease (CKD), which tends to have an earlier onset and a more rapid progression in this population. Many of the factors responsible for the rapid progression of CKD in African Americans are detectable by screening and are modifiable with prompt therapy.

  1. Representations of the Racialized Experiences of African Americans in Developmental Reading Textbooks

    Science.gov (United States)

    Williams, Jeanine L.

    2013-01-01

    Race plays a major role in the lived experiences of African Americans. Consequently, race significantly impacts the identities and educational experiences of African American college students--many of whom require developmental reading courses. These courses, which are gateway courses in higher education, should address race along with reading…

  2. A Campus-Community Partnership to Disseminate Health Internet Technology Resources among African Americans

    Science.gov (United States)

    Littlefield, Melissa B.; Edwards, Lorece; Akers, Timothy

    2014-01-01

    The Internet is increasingly used to disseminate health information about diseases and prevention and to help in obtaining health services. Although technology can empower African Americans to adopt healthy lifestyles, the gap in usage between African Americans and Whites undermines the potential power of health Internet technology (IT) to…

  3. Racial Discrimination, Coping, Life Satisfaction, and Self-Esteem among African Americans.

    Science.gov (United States)

    Utsey, Shawn O.; Ponterotto, Joseph G.; Reynolds, Amy L.; Cancelli, Anthony A.

    2000-01-01

    Study examines the coping strategies used by African Americans in managing the stressful effects of racism. Results indicate that women preferred avoidance coping for racism experienced on a personal level. For African Americans in general, seeking social support and racism condition were the best predictors of racism-related stress. Life…

  4. Meeting the Learning Needs of African American Youth in the Library

    Science.gov (United States)

    Hodges, Janice; Pringle, Lajuan S.

    2013-01-01

    The African American male psyche is a complicated multi-layered mixture of outside media influences, stereotypes, peer pressure, how they see themselves, and how they think others see them. This article describes how school and public librarians can help raise the literacy efforts of young African American males. It cites the need for libraries to…

  5. African American English and Spelling: How Do Second Graders Spell Dialect-Sensitive Features of Words?

    Science.gov (United States)

    Patton-Terry, Nicole; Connor, Carol

    2010-01-01

    This study explored the spelling skills of African American second graders who produced African American English (AAE) features in speech. The children (N = 92), who varied in spoken AAE use and word reading skills, were asked to spell words that contained phonological and morphological dialect-sensitive (DS) features that can vary between AAE and…

  6. Spelling in African American Children: The Case of Final Consonant Devoicing

    Science.gov (United States)

    Treiman, Rebecca; Bowman, Margo

    2015-01-01

    This study examined the effect of dialect variation on children's spelling by using devoicing of final /d/ in African American Vernacular English (AAVE) as a test case. In line with the linguistic interference hypothesis, African American 6-year-olds were significantly poorer at spelling the final "d" of words such as "salad"…

  7. Connective Complexity: African American Adolescents and the Relational Context of Kinship Foster Care

    Science.gov (United States)

    Schwartz, Ann

    2008-01-01

    Attempts to address racial disproportionality in child welfare must include a focus on the benefits and challenges facing children in kinship care. African American children not only are overrepresented in the child welfare system, but also are placed disproportionately in kinship foster care. Using a sample of 18 African American adolescents ages…

  8. African Americans among Degree Recipients in Physics and Geoscience. Focus On

    Science.gov (United States)

    Czujko, Roman; Nicholson, Starr

    2010-01-01

    Physics and geoscience consistently rank near the bottom among all disciplines in their ability to attract and retain African American students. Before delving into these trends, it is important to establish a context for discussing the data and their implications. African Americans comprise 12.4% of the U.S. population, but their representation…

  9. Taking Boys out of the Hood: Exile as a Parenting Strategy for African American Male Youth

    Science.gov (United States)

    Richardson, Joseph B., Jr.; Van Brakle, Mischelle; St. Vil, Christopher

    2014-01-01

    Research indicates that inner-city neighborhood effects are correlated with school dropout, substance abuse, crime, violence, homicide, HIV risk related behaviors, and incarceration for adolescent African American males. Parents of adolescent African American males face many challenges as they try to keep their children safe in high-risk…

  10. African-American Youth Perceptions of Alcohol Advertisements: A Preliminary Analysis.

    Science.gov (United States)

    More, Timothy; Taylor, David; Turner, Dion

    1998-01-01

    Examines motivational factors associated with malt liquor consumption in African American youth. (Malt liquor is directly marketed to African-American youth.) Over 90% of respondents consumed alcohol in the past. Students viewed malt liquor commercials as being more associated with sex and power than were beer commercials. (MMU)

  11. Acculturation Style and Alcohol Use among African American College Students: An Exploration of Potential Moderators

    Science.gov (United States)

    Abdullah, Tahirah; Brown, Tamara L.

    2012-01-01

    This study examined whether a relationship exists between acculturation and alcohol use among African American college students and if the relationship varies by religiosity and gender. Most researchers use unidimensional African American acculturation measures that cannot capture the construct's complexity; this study is the first to use a…

  12. Meaningful Learning with African American Families: The Freedom Quilt FunPacks

    Science.gov (United States)

    Powell-Mikle, Angiline; Patton, Mary Martin

    2004-01-01

    Despite some characterization as being uninvolved in the education of their children, African American parents have always valued education and recognized it as the key to economic and political freedom. Despite laws in the United States prohibiting the education of slaves, African Americans were the first southerners to campaign for universal,…

  13. Issues in Education: African American Male-Only Schools. Is That the Solution?

    Science.gov (United States)

    Greathouse, Betty; Sparling, Saundra

    1993-01-01

    Examines the advantages and disadvantages of African-American male-only classes and schools, which are staffed mainly by African-American male teachers. Focuses on attempts to create such institutions in Detroit, Baltimore, Milwaukee, and Dade County, Florida. (MDM)

  14. Cohesive Adequacy in the Narrative Samples of School-Age Children Who Use African American English

    Science.gov (United States)

    Horton-Ikard, RaMonda

    2009-01-01

    Purpose: This study explored the type and adequacy of cohesive devices that are produced by school-age children who use African American English (AAE). Method: The language samples of 33 African American children, ages 7, 9, and 11 years, were transcribed, analyzed, and coded for AAE use and cohesive adequacy (e.g., personal reference,…

  15. Influences of Social and Style Variables on Adult Usage of African American English Features

    Science.gov (United States)

    Craig, Holly K.; Grogger, Jeffrey T.

    2012-01-01

    Purpose: In this study, the authors examined the influences of selected social (gender, employment status, educational achievement level) and style variables (race of examiner, interview topic) on the production of African American English (AAE) by adults. Method: Participants were 50 African American men and women, ages 20-30 years. The authors…

  16. Bidialectal African American Adolescents' Beliefs about Spoken Language Expectations in English Classrooms

    Science.gov (United States)

    Godley, Amanda; Escher, Allison

    2012-01-01

    This article describes the perspectives of bidialectal African American adolescents--adolescents who speak both African American Vernacular English (AAVE) and Standard English--on spoken language expectations in their English classes. Previous research has demonstrated that many teachers hold negative views of AAVE, but existing scholarship has…

  17. School Adjustment and the Academic Success of Rural African American Early Adolescents in the Deep South

    Science.gov (United States)

    Farmer, Thomas W.; Irvin, Matthew J.; Thompson, Jana H.; Hutchins, Bryan C.; Leung, Man-Chi

    2006-01-01

    This study examined the relationship between end-of-year grades and the academic, behavioral, and social characteristics of rural African American youth. Participants included 392 7th and 8th grade students from 2 rural middle schools in the south. Participants were African American and were from 2 communities that have child poverty rates…

  18. "Putting Herself on the Line": African American Female Teacher Leaders as Exemplars of Social Justice Leadership

    Science.gov (United States)

    Robinson, Sheila Teel; Baber, Ceola Ross

    2013-01-01

    Existing scholarship on teacher leadership fails to account for the perspectives of African American female teacher leaders. In this article, we profile 3 African American female teacher leaders located at different trajectories on historical and professional timelines. Our analysis is grounded in understandings from the intersection of social…

  19. Incorporating Spirituality and Religion into the Treatment of African American Clients

    Science.gov (United States)

    Boyd-Franklin, Nancy

    2010-01-01

    This article discusses the process of incorporating spirituality and religion into the treatment of African American clients. It addresses religious diversity within the African American community. The roles of spirituality and religion as survival and coping mechanisms for overcoming racism, adversity, and loss are emphasized. The cases presented…

  20. Work Socialization and Adolescents' Work-Related Values in Single-Mother African American Families

    Science.gov (United States)

    Toyokawa, Teru; McLoyd, Vonnie C.

    2013-01-01

    This study examined African American mothers' work socialization messages in relation to adolescents' work-related values. Moderation effects of mother-adolescent relation quality on the linkage between maternal socialization messages and adolescents' outcomes were also examined. Participants were 245 single African American mothers and their…