WorldWideScience

Sample records for advancement research cpar

  1. Advanced research technology transfer

    International Nuclear Information System (INIS)

    Naraghi, Masud

    1977-01-01

    The importance of advanced research in the less developed countries of the world is described. Advanced research is a way of building from the top; it helps industrial development; it provides ''know-how'' economically; it enhances international understanding; it prevents the brain drain to developed countries and is of mutual benefit. The problems concerned with this type of research are pointed out

  2. Advancing Ethical Neuroscience Research.

    Science.gov (United States)

    Borah, B Rashmi; Strand, Nicolle K; Chillag, Kata L

    2016-12-01

    As neuroscience research advances, researchers, clinicians, and other stakeholders will face a host of ethical challenges. The Presidential Commission for the Study of Bioethical Issues (Bioethics Commission) has published two reports that provide recommendations on how to advance research endeavors ethically. The commission addressed, among other issues, how to prioritize different types of neuroscience research and how to include research participants who have impaired consent capacity. The Bioethics Commission's recommendations provide a foundation for ethical guidelines as neuroscience research advances and progresses. © 2016 American Medical Association. All Rights Reserved.

  3. Advanced maintenance research programs

    International Nuclear Information System (INIS)

    Marston, T.U.; Gelhaus, F.; Burke, R.

    1985-01-01

    The purpose of this paper is to provide the reader with an idea of the advanced maintenance research program at the Electric Power Research Institute (EPRI). A brief description of the maintenance-related activities is provided as a foundation for the advanced maintenance research projects. The projects can be divided into maintenance planning, preventive maintenance program development and implementation, predictive (or conditional) maintenance, and innovative maintenance techniques. The projects include hardware and software development, human factors considerations, and technology promotion and implementation. The advanced concepts include: the incorporation of artificial intelligence into outage planning; turbine and pump maintenance; rotating equipment monitoring and diagnostics with the aid of expert systems; and the development of mobile robots for nuclear power plant maintenance

  4. Advancing materials research

    International Nuclear Information System (INIS)

    Langford, H.D.; Psaras, P.A.

    1987-01-01

    The topics discussed in this volume include historical perspectives in the fields of materials research and development, the status of selected scientific and technical areas, and current topics in materials research. Papers are presentd on progress and prospects in metallurgical research, microstructure and mechanical properties of metals, condensed-matter physics and materials research, quasi-periodic crystals, and new and artifically structured electronic and magnetic materials. Consideration is also given to materials research in catalysis, advanced ceramics, organic polymers, new ways of looking at surfaces, and materials synthesis and processing

  5. Animal Production Research Advances

    African Journals Online (AJOL)

    Animal Production Research Advances is a peer-review journal established expressly to promote the production of all animal species utilized as food. The journal has an international scope and is intended for professionals in animal production and related sciences. We solicit contributions from animal production and ...

  6. NIH Research: Advances in Parkinson's Disease Research

    Science.gov (United States)

    ... of this page please turn JavaScript on. NIH Research: Advances in Parkinson's Disease Research Past Issues / Winter 2014 Table of Contents Story ... Photo courtesy of NIH Advances in Parkinson's Disease Research Story Landis, Ph.D., has been Director of ...

  7. [Research advances in dendrochronology].

    Science.gov (United States)

    Fang, Ke-Yan; Chen, Qiu-Yan; Liu, Chang-Zhi; Cao, Chun-Fu; Chen, Ya-Jun; Zhou, Fei-Fei

    2014-07-01

    Tree-ring studies in China have achieved great advances since the 1990s, particularly for the dendroclimatological studies which have made some influence around the world. However, because of the uneven development, limited attention has been currently paid on the other branches of dendrochronology. We herein briefly compared the advances of dendrochronology in China and of the world and presented suggestions on future dendrochronological studies. Large-scale tree-ring based climate reconstructions in China are highly needed by employing mathematical methods and a high quality tree-ring network of the ring-width, density, stable isotope and wood anatomy. Tree-ring based field climate reconstructions provide potentials on explorations of climate forcings during the reconstructed periods via climate diagnosis and process simulation.

  8. Animal Research International: Advanced Search

    African Journals Online (AJOL)

    PROMOTING ACCESS TO AFRICAN RESEARCH ... Animal Research International: Advanced Search ... containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ... Journal of Biomedical Research, African Journal of Biotechnology, African Journal of Chemical Education ...

  9. Advances in energy research

    CERN Document Server

    Acosta, Morena J

    2013-01-01

    This book presents a comprehensive review of energy research studies from authors around the globe, including recent research in new technologies associated with the construction of nuclear power plants; oil disperse systems study using nuclear magnetic resonance relaxometry (NMRR); low energy consumption for cooling and heating systems; experimental investigation of the performance of a ground-source heat pump system for buildings heating and cooling; sustainable development of bioenergy from agricultural wastes and the environment; hazard identification and parametric analysis of toxic pollutants dispersion from large liquid hydrocarbon fuel-tank fires; maintenance benchmarking in petrochemicals plants by means of a multicriteria model; wind energy development innovation; power, people and pollution; nature and technology of geothermal energy and clean sustainable energy for the benefit of humanity and the environment; and soil thermal properties and the effects of groundwater on closed loops.

  10. Advanced Remote Sensing Research

    Science.gov (United States)

    Slonecker, Terrence; Jones, John W.; Price, Susan D.; Hogan, Dianna

    2008-01-01

    'Remote sensing' is a generic term for monitoring techniques that collect information without being in physical contact with the object of study. Overhead imagery from aircraft and satellite sensors provides the most common form of remotely sensed data and records the interaction of electromagnetic energy (usually visible light) with matter, such as the Earth's surface. Remotely sensed data are fundamental to geographic science. The Eastern Geographic Science Center (EGSC) of the U.S. Geological Survey (USGS) is currently conducting and promoting the research and development of three different aspects of remote sensing science: spectral analysis, automated orthorectification of historical imagery, and long wave infrared (LWIR) polarimetric imagery (PI).

  11. Animal Production Research Advances: Submissions

    African Journals Online (AJOL)

    Where this is not possible, authors should submit two copies of original article not yet published anywhere and accompanied with a 3.5” diskette containing the article labeled appropriately in MS Word version to: Editor–in–Chief, Animal Production Research Advances Tropical Animal Health and Production Research Lab

  12. ADVANCED GAS TURBINE SYSTEMS RESEARCH

    Energy Technology Data Exchange (ETDEWEB)

    Unknown

    2002-04-01

    The activities of the Advanced Gas Turbine Systems Research (AGTSR) program for this reporting period are described in this quarterly report. The report is divided into discussions of Membership, Administration, Technology Transfer (Workshop/Education), Research and Miscellaneous Related Activity. Items worthy of note are presented in extended bullet format following the appropriate heading.

  13. ADVANCED GAS TURBINE SYSTEMS RESEARCH

    Energy Technology Data Exchange (ETDEWEB)

    Unknown

    2002-02-01

    The activities of the Advanced Gas Turbine Systems Research (AGTSR) program for this reporting period are described in this quarterly report. The report is divided into discussions of Membership, Administration, Technology Transfer (Workshop/Education), Research and Miscellaneous Related Activity. Items worthy of note are presented in extended bullet format following the appropriate heading.

  14. Research Staff | Advanced Manufacturing Research | NREL

    Science.gov (United States)

    manages wind turbine rotor blade composite manufacturing projects at the National Wind Technology Center postdoctoral researcher working to develop and validate advanced composite manufacturing processes using novel materials for wind and marine and hydrokinetic (MHK) turbines. This includes hands-on composite

  15. Translational research on advanced therapies

    Directory of Open Access Journals (Sweden)

    Filippo Belardelli

    2011-01-01

    Full Text Available Fostering translational research of advanced therapies has become a major priority of both scientific community and national governments. Advanced therapy medicinal products (ATMP are a new medicinal product category comprising gene therapy and cell-based medicinal products as well as tissue engineered medicinal products. ATMP development opens novel avenues for therapeutic approaches in numerous diseases, including cancer and neurodegenerative and cardiovascular diseases. However, there are important bottlenecks for their development due to the complexity of the regulatory framework, the high costs and the needs for good manufacturing practice (GMP facilities and new end-points for clinical experimentation. Thus, a strategic cooperation between different stakeholders (academia, industry and experts in regulatory issues is strongly needed. Recently, a great importance has been given to research infrastructures dedicated to foster translational medicine of advanced therapies. Some ongoing European initiatives in this field are presented and their potential impact is discussed.

  16. Translational research on advanced therapies.

    Science.gov (United States)

    Belardelli, Filippo; Rizza, Paola; Moretti, Franca; Carella, Cintia; Galli, Maria Cristina; Migliaccio, Giovanni

    2011-01-01

    Fostering translational research of advanced therapies has become a major priority of both scientific community and national governments. Advanced therapy medicinal products (ATMP) are a new medicinal product category comprising gene therapy and cell-based medicinal products as well as tissue engineered medicinal products. ATMP development opens novel avenues for therapeutic approaches in numerous diseases, including cancer and neurodegenerative and cardiovascular diseases. However, there are important bottlenecks for their development due to the complexity of the regulatory framework, the high costs and the needs for good manufacturing practice (GMP) facilities and new end-points for clinical experimentation. Thus, a strategic cooperation between different stakeholders (academia, industry and experts in regulatory issues) is strongly needed. Recently, a great importance has been given to research infrastructures dedicated to foster translational medicine of advanced therapies. Some ongoing European initiatives in this field are presented and their potential impact is discussed.

  17. Advanced research in data privacy

    CERN Document Server

    Torra, Vicenç

    2015-01-01

    This book provides an overview of the research work on data privacy and privacy enhancing technologies carried by the participants of the ARES project. ARES (Advanced Research in Privacy an Security, CSD2007-00004) has been one of the most important research projects funded by the Spanish Government in the fields of computer security and privacy. It is part of the now extinct CONSOLIDER INGENIO 2010 program, a highly competitive program which aimed to advance knowledge and open new research lines among top Spanish research groups. The project started in 2007 and will finish this 2014. Composed by 6 research groups from 6 different institutions, it has gathered an important number of researchers during its lifetime. Among the work produced by the ARES project, one specific work package has been related to privacy. This books gathers works produced by members of the project related to data privacy and privacy enhancing technologies. The presented works not only summarize important research carried in the proje...

  18. Selected advances in materials research

    International Nuclear Information System (INIS)

    Cunningham, J.E.

    1979-01-01

    Several findings emanating from materials research that should have a beneficial impact on technological advancement in the future are described. The report deals with the GRAPHNOL, a new class of high-temperature brazing alloy for joining refractory components, gel-sphere-pac process for manufacture of nuclear fuel, and noble-metal fuel cladding for service in radioisotope thermoelectric generators designed to provide auxiliary power aboard spacecraft for planetary exploration

  19. Bioenergy research advances and applications

    CERN Document Server

    Gupta, Vijai G; Kubicek, Christian P; Saddler, Jack; Xu, Feng

    2014-01-01

    Bioenergy Research: Advances and Applications brings biology and engineering together to address the challenges of future energy needs. The book consolidates the most recent research on current technologies, concepts, and commercial developments in various types of widely used biofuels and integrated biorefineries, across the disciplines of biochemistry, biotechnology, phytology, and microbiology. All the chapters in the book are derived from international scientific experts in their respective research areas. They provide you with clear and concise information on both standard and more recent bioenergy production methods, including hydrolysis and microbial fermentation. Chapters are also designed to facilitate early stage researchers, and enables you to easily grasp the concepts, methodologies and application of bioenergy technologies. Each chapter in the book describes the merits and drawbacks of each technology as well as its usefulness. The book provides information on recent approaches to graduates, post...

  20. Advancing neurosurgery through translational research.

    Science.gov (United States)

    Lacey, Claire; Sutherland, Garnette

    2013-01-01

    Every year, the number of published research articles increases significantly. However, many potentially useful ideas are lost in this flood of data. Translational research provides a framework through which investigators or laboratories can maximize the likelihood that the product of their research will be adopted in medical practice. There are 2 recognizable models of translation appropriate for the majority of research: investigator driven and industry enabled. Investigator-driven research has more range because it does not have to consider the profit margin of research, but it is a slow process. The industry-enabled model accelerates the translational research process through the power of industry funding but is interested primarily in products with potential for profit. Two cases are examined to illustrate different methods of partnering with industry. IMRIS is a company founded by investigators to distribute intraoperative magnetic resonance imaging technology based on a movable high-field magnet. It took 7 years for IMRIS to make its first sale, but it is now a successful company. With neuroArm, a surgical robot, investigators decided to sell the intellectual property to an established company to ensure successful global commercialization. Translational research advances medicine by creating and distributing effective solutions to contemporary problems.

  1. Animal Production Research Advances: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  2. Advancing Concentrating Solar Power Research (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2014-02-01

    Researchers at the National Renewable Energy Laboratory (NREL) provide scientific, engineering, and analytical expertise to help advance innovation in concentrating solar power (CSP). This fact sheet summarizes how NREL is advancing CSP research.

  3. Intermediate/Advanced Research Design and Statistics

    Science.gov (United States)

    Ploutz-Snyder, Robert

    2009-01-01

    The purpose of this module is To provide Institutional Researchers (IRs) with an understanding of the principles of advanced research design and the intermediate/advanced statistical procedures consistent with such designs

  4. Advanced research reactor fuel development

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chang Kyu; Pak, H. D.; Kim, K. H. [and others

    2000-05-01

    The fabrication technology of the U{sub 3}Si fuel dispersed in aluminum for the localization of HANARO driver fuel has been launches. The increase of production yield of LEU metal, the establishment of measurement method of homogeneity, and electron beam welding process were performed. Irradiation test under normal operation condition, had been carried out and any clues of the fuel assembly breakdown was not detected. The 2nd test fuel assembly has been irradiated at HANARO reactor since 17th June 1999. The quality assurance system has been re-established and the eddy current test technique has been developed. The irradiation test for U{sub 3}Si{sub 2} dispersed fuels at HANARO reactor has been carried out in order to compare the in-pile performance of between the two types of U{sub 3}Si{sub 2} fuels, prepared by both the atomization and comminution processes. KAERI has also conducted all safety-related works such as the design and the fabrication of irradiation rig, the analysis of irradiation behavior, thermal hydraulic characteristics, stress analysis for irradiation rig, and thermal analysis fuel plate, for the mini-plate prepared by international research cooperation being irradiated safely at HANARO. Pressure drop test, vibration test and endurance test were performed. The characterization on powders of U-(5.4 {approx} 10 wt%) Mo alloy depending on Mo content prepared by rotating disk centrifugal atomization process was carried out in order to investigate the phase stability of the atomized U-Mo alloy system. The {gamma}-U phase stability and the thermal compatibility of atomized U-16at.%Mo and U-14at.%Mo-2at.%X(: Ru, Os) dispersion fuel meats at an elevated temperature have been investigated. The volume increases of U-Mo compatibility specimens were almost the same as or smaller than those of U{sub 3}Si{sub 2}. However the atomized alloy fuel exhibited a better irradiation performance than the comminuted alloy. The RERTR-3 irradiation test of nano

  5. RESEARCH CENTRIFUGE- ADVANCED TOOL SEPERATION

    OpenAIRE

    Mahajan Ashwini; Prof. B.V. Jain; Dr Surajj Sarode

    2015-01-01

    A centrifuge is a critical piece of equipment for the laboratory. Purpose of this study was to study research centrifuge in detail, its applications, uses in different branches and silent features. Their are two types of research centrifuge study here revolutionary research centrifuge and microprocessor research centrifuge. A centrifuge is a device that separates particles from a solution through use of a rotor. In biology, the particles are usually cells, sub cellular organelles, or large mo...

  6. Advancing Microgrid Research at NREL

    Energy Technology Data Exchange (ETDEWEB)

    2018-04-25

    NREL expanded its microgrid research capabilities at the Energy System Integration Facility (ESIF) with the purchase of a Schweitzer Engineering Laboratories (SEL) microgrid controller, resulting in a more comprehensive microgrid research platform. NREL's microgrid research platform allows manufacturers, utilities, and integrators to develop and evaluate their technology or configuration at full power before implementation - something only possible at a handful of facilities in the world.

  7. Ethiopian Journal of Development Research: Advanced Search

    African Journals Online (AJOL)

    PROMOTING ACCESS TO AFRICAN RESEARCH ... Ethiopian Journal of Development Research: Advanced Search ... containing either term; e.g., education OR research; Use parentheses to create more complex queries; ... Ethiopian Journal of Business and Economics (The), Ethiopian Journal of Development Research ...

  8. Nigerian Journal of Chemical Research: Advanced Search

    African Journals Online (AJOL)

    PROMOTING ACCESS TO AFRICAN RESEARCH ... Nigerian Journal of Chemical Research: Advanced Search ... containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., .... and Applied Sciences, Nigerian Journal of Biotechnology, Nigerian Journal of Chemical Research ...

  9. Nontraditional machining processes research advances

    CERN Document Server

    2013-01-01

    Nontraditional machining employs processes that remove material by various methods involving thermal, electrical, chemical and mechanical energy or even combinations of these. Nontraditional Machining Processes covers recent research and development in techniques and processes which focus on achieving high accuracies and good surface finishes, parts machined without burrs or residual stresses especially with materials that cannot be machined by conventional methods. With applications to the automotive, aircraft and mould and die industries, Nontraditional Machining Processes explores different aspects and processes through dedicated chapters. The seven chapters explore recent research into a range of topics including laser assisted manufacturing, abrasive water jet milling and hybrid processes. Students and researchers will find the practical examples and new processes useful for both reference and for developing further processes. Industry professionals and materials engineers will also find Nontraditional M...

  10. African Research Review: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  11. Research advances in industrial engineering

    CERN Document Server

    2015-01-01

    This book provides discussions and the exchange of information on principles, strategies, models, techniques, methodologies and applications of industrial engineering. It communicates the latest developments and research activity on industrial engineering and is useful for all those interested in the technological challenges in the field.

  12. Advanced Energy Projects FY 1990 research summaries

    International Nuclear Information System (INIS)

    1990-09-01

    This report serves as a guide to prepare proposals and provides summaries of the research projects active in FY 1990, sponsored by the Office of Basic Energy Sciences Division of Advanced Energy Projects, Department of Energy. (JF)

  13. Bringing Advanced Computational Techniques to Energy Research

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, Julie C

    2012-11-17

    Please find attached our final technical report for the BACTER Institute award. BACTER was created as a graduate and postdoctoral training program for the advancement of computational biology applied to questions of relevance to bioenergy research.

  14. Advancing Research on Undergraduate Science Learning

    Science.gov (United States)

    Singer, Susan Rundell

    2013-01-01

    This special issue of "Journal of Research in Science Teaching" reflects conclusions and recommendations in the "Discipline-Based Education Research" (DBER) report and makes a substantial contribution to advancing the field. Research on undergraduate science learning is currently a loose affiliation of related fields. The…

  15. Advanced Research Reactor Fuel Development

    Energy Technology Data Exchange (ETDEWEB)

    Kim, C. K.; Park, H. D.; Kim, K. H. (and others)

    2006-04-15

    RERTR program for non-proliferation has propelled to develop high-density U-Mo dispersion fuels, reprocessable and available as nuclear fuel for high performance research reactors in the world. As the centrifugal atomization technology, invented in KAERI, is optimum to fabricate high-density U-Mo fuel powders, it has a great possibility to be applied in commercialization if the atomized fuel shows an acceptable in-reactor performance in irradiation test for qualification. In addition, if rod-type U-Mo dispersion fuel is developed for qualification, it is a great possibility to export the HANARO technology and the U-Mo dispersion fuel to the research reactors supplied in foreign countries in future. In this project, reprocessable rod-type U-Mo test fuel was fabricated, and irradiated in HANARO. New U-Mo fuel to suppress the interaction between U-Mo and Al matrix was designed and evaluated for in-reactor irradiation test. The fabrication process of new U-Mo fuel developed, and the irradiation test fuel was fabricated. In-reactor irradiation data for practical use of U-Mo fuel was collected and evaluated. Application plan of atomized U-Mo powder to the commercialization of U-Mo fuel was investigated.

  16. Research Advance in Smart Metamaterials

    Directory of Open Access Journals (Sweden)

    YU Xiang-long

    2016-07-01

    Full Text Available Metamaterials, man-made materials, enable us to design our own "atoms", and thereby to create materials with unprecedented effective properties that have not yet been found in nature. Smart metamaterial is one of those that is an intelligent perceptive to the changes from external environments and simultaneously having the capability to respond to thermal and mechanical stimuli. This paper can provide a review on these smart metamaterials in perspective of science, engineering and industrial products. We divide smart metamaterials according to what they are tuning into: optical, mechanical, thermal and coupled smart metamaterials. The rest of two techniques we addressed are modelling/simulation and fabrication/gene engineering. All of these types smart materials presented here are associated with at least five fundamental research: coupled mechanism of multi-physics fields, man-made design for atom/molecular, metamaterials coupled with natural materials, tunability of metamaterials, and mechanism of sensing metamaterials. Therefore, we give a systematic overview of various potential smart metamaterials together with the upcoming challenges in the intriguing and promising research field.

  17. Advanced accelerator research and development

    International Nuclear Information System (INIS)

    Anon.

    1974-01-01

    Research and development on the Positron-Electron Project (PEP), the electron rings, the superconducting accelerator (ESCAR), and the superconductivity program are reported. Efforts relating to the proposed PEP include work on: (1) the injection system; (2) the rf system; (3) the main-ring bend magnets; (4) the magnet power supplies and controls; (5) alignment; (6) radiation and shielding; (7) the vacuum system; and (8) conventional facilities (utilities, etc.). Experimental and theoretical work continued on the development of suitably intense electron rings as vehicles for the collective acceleration of ions. The most difficult problem was found to be the longitudinal (negative mass) instability. Design work was begun for ESCAR (Experimental Superconducting Accelerating Ring), a small proton synchrotron and storage ring using superconducting magnets, which should aid in the design of future large superconducting facilities. Magnet development was largely directed toward the detailed design of the dipole units. A superconducting beam transport line was installed at the Bevatron. (PMA)

  18. Traditional machining processes research advances

    CERN Document Server

    2015-01-01

    This book collects several examples of research in machining processes. Chapter 1 provides information on polycrystalline diamond tool material and its emerging applications. Chapter 2 is dedicated to the analysis of orthogonal cutting experiments using diamond-coated tools with force and temperature measurements. Chapter 3 describes the estimation of cutting forces and tool wear using modified mechanistic models in high performance turning. Chapter 4 contains information on cutting under gas shields for industrial applications. Chapter 5 is dedicated to the machinability of magnesium and its alloys. Chapter 6 provides information on grinding science. Finally, chapter 7 is dedicated to flexible integration of shape and functional modelling of machine tool spindles in a design framework.    

  19. Introduction: Recent advances in expertise research.

    NARCIS (Netherlands)

    Rikers, Remy; Paas, Fred

    2007-01-01

    During the 55th meeting of the American Educational Research Association (AERA, 2004) in San Diego, a symposium was organized on Recent Advances in Expertise Research. Most papers in this special issue of Applied Cognitive Psychology were presented in this symposium. The aim of this special issue is

  20. Advancing Normal Birth: Organizations, Goals, and Research

    OpenAIRE

    Hotelling, Barbara A.; Humenick, Sharron S.

    2005-01-01

    In this column, the support for advancing normal birth is summarized, based on a comparison of the goals of Healthy People 2010, Lamaze International, the Coalition for Improving Maternity Services, and the midwifery model of care. Research abstracts are presented to provide evidence that the midwifery model of care safely and economically advances normal birth. Rates of intervention experienced, as reported in the Listening to Mothers survey, are compared to the forms of care recommended by ...

  1. Physics and safety of advanced research reactors

    International Nuclear Information System (INIS)

    Boening, K.; Hardt, P. von der

    1987-01-01

    Advanced research reactor concepts are presently being developed in order to meet the neutron-based research needs of the nineties. Among these research reactors, which are characterized by an average power density of 1-10 MW per liter, highest priority is now generally given to the 'beam tube reactors'. These provide very high values of the thermal neutron flux (10 14 -10 16 cm -2 s -1 ) in a large volume outside of the reactor core, which can be used for sample irradiations and, in particular, for neutron scattering experiments. The paper first discusses the 'inverse flux trap concept' and the main physical aspects of the design and optimization of beam tube reactors. After that two examples of advanced research reactor projects are described which may be considered as two opposite extremes with respect to the physical optimization principle just mentioned. The present situation concerning cross section libraries and neutronic computer codes is more or less satisfactory. The safety analyses of advanced research reactors can largely be updated from those of current new designs, partially taking advantage of the immense volume of work done for power reactors. The paper indicates a few areas where generic problems for advanced research reactor safety are to be solved. (orig.)

  2. NATO Advanced Research Workshop on Molecular Engineering for Advanced Materials

    CERN Document Server

    Schaumburg, Kjeld

    1995-01-01

    An important aspect of molecular engineering is the `property directed' synthesis of large molecules and molecular assemblies. Synthetic expertise has advanced to a state which allows the assembly of supramolecules containing thousands of atoms using a `construction kit' of molecular building blocks. Expansion in the field is driven by the appearance of new building blocks and by an improved understanding of the rules for joining them in the design of nanometer-sized devices. Another aspect is the transition from supramolecules to materials. At present no single molecule (however large) has been demonstrated to function as a device, but this appears to be only a matter of time. In all of this research, which has a strongly multidisciplinary character, both existing and yet to be developed analytical techniques are and will remain indispensable. All this and more is discussed in Molecular Engineering for Advanced Materials, which provides a masterly and up to date summary of one of the most challenging researc...

  3. Animal Production Research Advances: Editorial Policies

    African Journals Online (AJOL)

    Focus and Scope. Animal production research advances is a peer-review journal established expressly to promote the production of all animal species utilized as food. The journal has an international scope and is intended for professionals in animal production and related sciences. We solicit contributions from animal ...

  4. Advanced energy projects FY 1992 research summaries

    International Nuclear Information System (INIS)

    1992-09-01

    The Division of Advanced Energy Projects (AEP) provides support to explore the feasibility of novel, energy-related concepts that evolve from advances in basic research. These concepts are typically at an early stage of scientific definition and, therefore, are beyond the scope of ongoing applied research or technology development programs. The Division provides a mechanism for converting basic research findings to applications that eventually could impact the Nation's energy economy. Technical topics include physical, chemical, materials, engineering, and biotechnologies. Projects can involve interdisciplinary approaches to solve energy-related problems. Projects are supported for a finite period of time, which is typically three years. Annual funding levels for projects are usually about $300,000 but can vary from approximately $50,000 to $500,000. It is expected that, following AEP support, each concept will be sufficiently developed and promising to attract further funding from other sources in order to realize its full potential. There were 39 research projects in the Division of Advanced Energy Projects during Fiscal Year 1992 (October 1, 1991 -- September 30, 1992). The abstracts of those projects are provided to introduce the overall program in Advanced Energy Projects. Further information on a specific project may be obtained by contacting the principal investigator, who is listed below the project title. Projects completed during FY 1992 are indicated

  5. Coordinating Space Nuclear Research Advancement and Education

    International Nuclear Information System (INIS)

    Bess, John D.; Webb, Jonathon A.; Gross, Brian J.; Craft, Aaron E.

    2009-01-01

    The advancement of space exploration using nuclear science and technology has been a goal sought by many individuals over the years. The quest to enable space nuclear applications has experienced many challenges such as funding restrictions; lack of political, corporate, or public support; and limitations in educational opportunities. The Center for Space Nuclear Research (CSNR) was established at the Idaho National Laboratory (INL) with the mission to address the numerous challenges and opportunities relevant to the promotion of space nuclear research and education.1 The CSNR is operated by the Universities Space Research Association and its activities are overseen by a Science Council comprised of various representatives from academic and professional entities with space nuclear experience. Program participants in the CSNR include academic researchers and students, government representatives, and representatives from industrial and corporate entities. Space nuclear educational opportunities have traditionally been limited to various sponsored research projects through government agencies or industrial partners, and dedicated research centers. Centralized research opportunities are vital to the growth and development of space nuclear advancement. Coordinated and focused research plays a key role in developing the future leaders in the space nuclear field. The CSNR strives to synchronize research efforts and provide means to train and educate students with skills to help them excel as leaders.

  6. Using Lean to Advance Quality Improvement Research.

    Science.gov (United States)

    Blackmore, Christopher Craig; Williams, Barbara L; Ching, Joan M; Chafetz, Lynne A; Kaplan, Gary S

    2016-01-01

    Quality improvement research skills are not commonplace among quality improvement practitioners, and research on the effectiveness of quality improvement has not always kept pace with improvement innovation. However, the Lean tools applied to quality improvement should be equally relevant to the advancement of quality improvement research. We applied the Lean methods to develop a simplified quality improvement publication pathway enabling a small research methodology group to increase quality improvement research throughout the institution. The key innovations of the pathway are horizontal integration of the quality improvement research methods group across the institution, implementation of a Lean quality improvement research pathway, and application of a just-in-time quality improvement research toolkit. This work provides a road map and tools for the acceleration of quality improvement research. At our institution, the Lean quality improvement research approach was associated with statistically significant increases in the number (annual mean increase from 3.0 to 8.5, p = .03) and breadth of published quality improvement research articles, and in the number of quality improvement research projects currently in process. Application of Lean methods to the quality improvement research process can aid in increasing publication of quality improvement articles from across the institution.

  7. Aims of advanced photon science research

    International Nuclear Information System (INIS)

    Kimura, Toyoaki

    2004-01-01

    The Advanced Photon Research Center (APRC) of Japan Atomic Energy Research Institute is pursing the research and development of advanced photon sources such as a compact, ultra-short, high intensity laser, x-ray laser, and a superconducting linac-based free electron laser (FEL) and their applications. These compact and high-intensity lasers have various capabilities of producing radiations with distinguishing characteristics of ultra-short pulse, high coherence, etc. Hence, they can provide novel means of research in the field of nuclear energy applications and industrial and medical technologies. It is important for us to promote these researches on these high-intensity laser applications comprehensively and effectively under the collaborations with nationwide universities and industry. From this point of view it is expected that the APRC plays a role as a COE for these researches. Through these research activities for development of high-intensity lasers and their applications, we will develop ''photon science and technology'' as a leading key technology in the 21st century and contribute the development of science and technology including nuclear energy technology and production of new industries. (author)

  8. Advanced energy projects FY 1997 research summaries

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-09-01

    The mission of the Advanced Energy Projects (AEP) program is to explore the scientific feasibility of novel energy-related concepts that are high risk, in terms of scientific feasibility, yet have a realistic potential for a high technological payoff. The concepts supported by the AEP are typically at an early stage of scientific development. They often arise from advances in basic research and are premature for consideration by applied research or technology development programs. Some are based on discoveries of new scientific phenomena or involve exploratory ideas that span multiple scientific and technical disciplines which do not fit into an existing DOE program area. In all cases, the objective is to support evaluation of the scientific or technical feasibility of the novel concepts involved. Following AEP support, it is expected that each concept will be sufficiently developed to attract further funding from other sources to realize its full potential. Projects that involve evolutionary research or technology development and demonstration are not supported by AEP. Furthermore, research projects more appropriate for another existing DOE research program are not encouraged. There were 65 projects in the AEP research portfolio during Fiscal Year 1997. Eigheen projects were initiated during that fiscal year. This document consists of short summaries of projects active in FY 1997. Further information of a specific project may be obtained by contacting the principal investigator.

  9. [Research Advances in Cyprinid Herpesvirus 3].

    Science.gov (United States)

    Zheng, Shucheng; Wang, Qing; Li, Yingying; Zeng, Weiwei; Wang, Yingying; Liu, Chun; Liang, Hongru; Shi, Cunbin

    2016-01-01

    Cyprinid herpesvirus 3 (CyHV-3) is the causative agent of an extremely contagious and aggressive disease afflicting common corp Cyprinus carpio L. termed koi herpesvirus disease (KHVD). Since it was first reported in 1997, the virus has spread worldwide rapidly, leading to enormous financial losses in industries based on common carp and koi carp. This review summarizes recent advances in CyHV-3 research on the etiology, epidemiology, pathogenesis, diagnosis, prevention, and control of KHVD.

  10. Medical technology advances from space research

    Science.gov (United States)

    Pool, S. L.

    1972-01-01

    Details of medical research and development programs, particularly an integrated medical laboratory, as derived from space technology are given. The program covers digital biotelemetry systems, automatic visual field mapping equipment, sponge electrode caps for clinical electroencephalograms, and advanced respiratory analysis equipment. The possibility of using the medical laboratory in ground based remote areas and regional health care facilities, as well as long duration space missions is discussed.

  11. Research Institute for Advanced Computer Science

    Science.gov (United States)

    Gross, Anthony R. (Technical Monitor); Leiner, Barry M.

    2000-01-01

    The Research Institute for Advanced Computer Science (RIACS) carries out basic research and technology development in computer science, in support of the National Aeronautics and Space Administration's missions. RIACS is located at the NASA Ames Research Center. It currently operates under a multiple year grant/cooperative agreement that began on October 1, 1997 and is up for renewal in the year 2002. Ames has been designated NASA's Center of Excellence in Information Technology. In this capacity, Ames is charged with the responsibility to build an Information Technology Research Program that is preeminent within NASA. RIACS serves as a bridge between NASA Ames and the academic community, and RIACS scientists and visitors work in close collaboration with NASA scientists. RIACS has the additional goal of broadening the base of researchers in these areas of importance to the nation's space and aeronautics enterprises. RIACS research focuses on the three cornerstones of information technology research necessary to meet the future challenges of NASA missions: (1) Automated Reasoning for Autonomous Systems. Techniques are being developed enabling spacecraft that will be self-guiding and self-correcting to the extent that they will require little or no human intervention. Such craft will be equipped to independently solve problems as they arise, and fulfill their missions with minimum direction from Earth; (2) Human-Centered Computing. Many NASA missions require synergy between humans and computers, with sophisticated computational aids amplifying human cognitive and perceptual abilities; (3) High Performance Computing and Networking. Advances in the performance of computing and networking continue to have major impact on a variety of NASA endeavors, ranging from modeling and simulation to data analysis of large datasets to collaborative engineering, planning and execution. In addition, RIACS collaborates with NASA scientists to apply information technology research to a

  12. Advancing research on loyalty programs: a future research agenda

    OpenAIRE

    Breugelmans, Els; Bijmolt, Tammo H. A.; Zhang, Jie; Basso, Leonardo J.; Dorotic, Matilda; Kopalle, Praveen; Minnema, Alec; Mijnlieff, Willem Jan; Wünderlich, Nancy V.

    2015-01-01

    This is the authors’ accepted and refereed manuscript to the article Despite the growing literature on loyalty program (LP) research, many questions remain underexplored. Driven by advancements in information technology, marketing analytics, and consumer interface platforms (e.g., mobile devices), there have been many recent developments in LP practices around the world. They impose new challenges and create exciting opportunities for future LP research. The main objective of this paper is...

  13. Research opportunities to advance solar energy utilization.

    Science.gov (United States)

    Lewis, Nathan S

    2016-01-22

    Major developments, as well as remaining challenges and the associated research opportunities, are evaluated for three technologically distinct approaches to solar energy utilization: solar electricity, solar thermal, and solar fuels technologies. Much progress has been made, but research opportunities are still present for all approaches. Both evolutionary and revolutionary technology development, involving foundational research, applied research, learning by doing, demonstration projects, and deployment at scale will be needed to continue this technology-innovation ecosystem. Most of the approaches still offer the potential to provide much higher efficiencies, much lower costs, improved scalability, and new functionality, relative to the embodiments of solar energy-conversion systems that have been developed to date. Copyright © 2016, American Association for the Advancement of Science.

  14. UZIG USGS research: Advances through interdisciplinary interaction

    Science.gov (United States)

    Nimmo, J.R.; Andraski, Brian J.; Rafael, M.-C.

    2009-01-01

    BBecause vadose zone research relates to diverse disciplines, applications, and modes of research, collaboration across traditional operational and topical divisions is especially likely to yield major advances in understanding. The Unsaturated Zone Interest Group (UZIG) is an informal organization sponsored by the USGS to encourage and support interdisciplinary collaboration in vadose or unsaturated zone hydrologic research across organizational boundaries. It includes both USGS and non-USGS scientists. Formed in 1987, the UZIG operates to promote communication, especially through periodic meetings with presentations, discussions, and field trips. The 10th meeting of the UZIG at Los Alamos, NM, in August 2007 was jointly sponsored by the USGS and Los Alamos National Laboratory. Presentations at this meeting served as the initial basis for selecting papers for this special section of Vadose Zone Journal, the purpose of which is to present noteworthy cutting-edge unsaturated zone research promoted by, facilitated by, or presented in connection with the UZIG.

  15. Advanced energy projects FY 1994 research summaries

    International Nuclear Information System (INIS)

    1994-09-01

    The Division of Advanced Energy Projects (AEP) provides support to explore the feasibility of novel, energy-related concepts that evolve from advances in basic research. These concepts are typically at an early stage of scientific definition and, therefore, are premature for consideration by applied research or technology development programs. The AEP also supports high-risk, exploratory concepts that do not readily fit into a program area but could have several applications that may span scientific disciplines or technical areas. Projects supported by the Division arise from unsolicited ideas and concepts submitted by researchers. The portfolio of projects is dynamic and reflects the broad role of the Department in supporting research and development for improving the Nation's energy outlook. FY 1994 projects include the following topical areas: novel materials for energy technology; renewable and biodegradable materials; exploring uses of new scientific discoveries; alternate pathways to energy efficiency; alternative energy sources; and innovative approaches to waste treatment and reduction. Summaries are given for 66 projects

  16. Advanced energy projects: FY 1987 research summaries

    International Nuclear Information System (INIS)

    1987-09-01

    This report contains brief summaries of all projects active in the Division of Advanced Energy Projects during Fiscal Year 1987 (October 1, 1986-September 30, 1987). The intent of this compilation is to provide a convenient means for quickly acquainting an interested reader with the program in Advanced Energy Projects. More detailed information on research activities in a particular project may be obtained by contacting directly the principal investigator. Some projects will have reached the end of their contract periods by the time this book appears, and will, therefore, no longer be active. Those cases in which work was completed in FY '87 are indicated by the footnote: Project completed. The annual funding level of each project is shown

  17. [Advances in genetic research of cerebral palsy].

    Science.gov (United States)

    Wang, Fang-Fang; Luo, Rong; Qu, Yi; Mu, De-Zhi

    2017-09-01

    Cerebral palsy is a group of syndromes caused by non-progressive brain injury in the fetus or infant and can cause disabilities in childhood. Etiology of cerebral palsy has always been a hot topic for clinical scientists. More and more studies have shown that genetic factors are closely associated with the development of cerebral palsy. With the development and application of various molecular and biological techniques such as chromosome microarray analysis, genome-wide association study, and whole exome sequencing, new achievements have been made in the genetic research of cerebral palsy. Chromosome abnormalities, copy number variations, susceptibility genes, and single gene mutation associated with the development of cerebral palsy have been identified, which provides new opportunities for the research on the pathogenesis of cerebral palsy. This article reviews the advances in the genetic research on cerebral palsy in recent years.

  18. Geysers advanced direct contact condenser research

    Energy Technology Data Exchange (ETDEWEB)

    Henderson, J.; Bahning, T.; Bharathan, D.

    1997-12-31

    The first geothermal application of the Advanced Direct Contact Condenser (ADCC) technology developed by the National Renewable Energy Laboratory (NREL) is now operational and is being tested at The Geysers Power Plant Unit 11. This major research effort is being supported through the combined efforts of NREL, The Department of Energy (DOE), and Pacific Gas and Electric (PG&E). NREL and PG&E have entered into a Cooperative Research And Development Agreement (CRADA) for a project to improve the direct-contact condenser performance at The Geysers Power Plant. This project is the first geothermal adaptation of an advanced condenser design developed for the Ocean Thermal Energy Conversion (OTEC) systems. PG&E expects this technology to improve power plant performance and to help extend the life of the steam field by using steam more efficiently. In accordance with the CRADA, no money is transferred between the contracting parties. In this case the Department of Energy is funding NREL for their efforts in this project and PG&E is contributing funds in kind. Successful application of this technology at The Geysers will provide a basis for NREL to continue to develop this technology for other geothermal and fossil power plant systems.

  19. Advancing LGBTQI2 rights in developing countries through research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2018-05-10

    May 10, 2018 ... Advancing LGBTQI2 rights in developing countries through research ... the role of research in advancing the rights of lesbian, gay, bisexual, transgender, ... cities were discussed at ADAPTO's second international workshop.

  20. New advances in gastrointestinal motility research

    CERN Document Server

    Pullan, A; Farrugia, G

    2013-01-01

    Research into gastrointestinal motility has received renewed interest in part due to recent advances in the techniques for measuring the structure and function of gastrointestinal cells, tissue and organs. The integration of this wealth of data into biophysically based computation models can aid in interpretation of experimental and clinical measurements and the refinement of measurement techniques. The contents of this book span multiple scales - from cell, tissue, organ, to whole body and is divided into four broad sections covering: i) gastrointestinal cellular activity and tissue structure; (ii) techniques for measuring, analyzing and visualizing high-resolution extra-cellular recordings; (iii) methods for sensing gastroelectrical activity using non-invasive bio-electro-magnetic fields and for modulating the underlying gastric electrical activity, and finally; (iv) methods for assessing manometric and videographic motility patterns and the application of these data for predicting the flow and mixing behav...

  1. Advances in research on Zika virus

    Institute of Scientific and Technical Information of China (English)

    Amjad Ali; Braira Wahid; Shazia Rafique; Muhammad Idrees

    2017-01-01

    Zika virus (ZIKV) is rapidly spreading across the America and its devastating outcomes for pregnant women and infants have driven this previously ignored pathogen into the limelight. Clinical manifestations are fever, joint pain or rash and conjunctivitis. Emergence of ZIKV started with a first outbreak in the Pacific area in 2007, a second large outbreak occurred in the Pacific in 2013/2014 and subsequently the virus spread in other Pacific islands. Threat of explosive global pandemic and severe clinical complications linked with the more immediate and recurrent epidemics necessitate the development of an effective vaccine. Several vaccine platforms such as DNA vaccine, recombinant subunit vaccine, ZIKV purified inactivated vaccine, and chimeric vaccines have shown potent efficacyin vitro andin vivo trials. Moreover, number of drugs such as Sofosbuvir, BCX4450, NITD008 and 7-DMA are ready to enter phase I clinical trial because of proven anti-ZIKV activity. Monoclonal based antibodies offer promise as an intervention effective for use in pregnant women. In this review, we describe the advances in research on ZIKV such as research strategies for the development of antiviral drugs & vaccines, molecular evolution, epidemiology emergence, neurological complications and other teratogenic outcomes as well as pathogenesis.

  2. Advances in Functionalized Materials Research 2016

    International Nuclear Information System (INIS)

    Predoi, D.; Motelica-Heino, M.; Guegan, R.; Coustumer, L.Ph.

    2016-01-01

    In the last years, due to the rapid progress of technology, new materials at nano metric scale with special properties have become a flourishing field of research in materials science. The unique physicochemical properties of materials induced by various parameters such as mean size, shape, purity, crystallographic structure, and surface can generate effective solutions to challenging environmental and biomedical problems. As a result of this approach a large number of techniques were developed that enable obtaining novel materials at nano metric scale with specific and reproducible properties and parameters. Below will be highlighted studies on promising properties on the applicability of new materials that could lead to innovative applications in the medical field. Therefore, this special issue is focused on expected advances in the area of functionalized materials at nano metric scale. Due to multidisciplinarity of this topic, this special issue is comprised of a wide range of original research articles as well as review papers on the design and synthesis of functionalized nano materials, their structural, morphological, and biological characterization, and their potential uses in medical and environmental applications

  3. Advanced tokamak research in DIII-D

    International Nuclear Information System (INIS)

    Greenfield, C M; Murakami, M; Ferron, J R

    2004-01-01

    Advanced tokamak (AT) research in DIII-D seeks to provide a scientific basis for steady-state high performance operation in future devices. These regimes require high toroidal beta to maximize fusion output and high poloidal beta to maximize the self-driven bootstrap current. Achieving these conditions requires integrated, simultaneous control of the current and pressure profiles and active magnetohydrodynamic stability control. The building blocks for AT operation are in hand. Resistive wall mode stabilization by plasma rotation and active feedback with non-axisymmetric coils allows routine operation above the no-wall beta limit. Neoclassical tearing modes are stabilized by active feedback control of localized electron cyclotron current drive (ECCD). Plasma shaping and profile control provide further improvements. Under these conditions, bootstrap supplies most of the current. Steady-state operation requires replacing the remaining inductively driven current, mostly located near the half radius, with non-inductive external sources. In DIII-D this current is provided by ECCD, and nearly stationary AT discharges have been sustained with little remaining inductive current. Fast wave current drive is being developed to control the central magnetic shear. Density control, with divertor cryopumps, of AT discharges with ELMing H-mode edges facilitates high current drive efficiency at reactor relevant collisionalities. An advanced plasma control system allows integrated control of these elements. Close coupling between modelling and experiment is key to understanding the separate elements, their complex nonlinear interactions, and their integration into self-consistent high performance scenarios. This approach has resulted in fully non-inductively driven plasmas with β N ≤ 3.5 and β T ≤ 3.6% sustained for up to 1 s, which is approximately equal to one current relaxation time. Progress in this area, and its implications for next-step devices, will be illustrated by

  4. Research on CDA for advanced fuel FBR

    International Nuclear Information System (INIS)

    Hirano, Go; Hirakawa, Naohiro; Kawada, Ken-ichi; Niwa, Hazime.

    1997-03-01

    For the purpose of evaluating possibility of the re-criticality of a metallic fueled reactor, Tohoku university and Power Reactor and Nuclear Fuel Development Corporation have made a joint research entitled 'Research on CDA for advanced fuel FBR'. The results of this year are the following. The accident initiator considered is a loss-of-flow accident with ATWS. The LOF analysis was performed for the metallic fueled 600 MWe homogeneous two region reactors, both for a metallic fuel only and for a metallic fuel core with ZrH pin. The SAS3D CDA initiation phase analysis code was used to investigate the re-criticality potential at the severe accident. The change mainly in the constants was necessary to apply the code for the analysis of a metallic fueled reactor. These changes were made by assuming appropriate models. LOF with flow decay half time of t 1/2 =0.5(s) (all blackout case) and 5.5(s) (ordinary LOF case) were analyzed. Independent of the conditions of the analysis, the results show all the cases could avoid to become prompt-critical. Depending on the analysis condition, it becomes necessary to transfer to the transient phase, it is also shown there is a possibility to avoid re-criticality due to the motion of molten fuel both for the metallic fuel and for the metallic fuel with ZrH moderator. However, because of the constants used for the material property the results might overestimate the fuel motion. It is shown that the moderator is effective to terminate the accident at an early stage. The behavior of metallic fueled reactors at CDA was analyzed with SAS3D code by modifying the constants of material properties to be applied to the reactor. It is shown that a metallic fueled reactor has a possibility to avoid re-criticality at CDA. (J.P.N.)

  5. Advanced research workshop: nuclear materials safety

    International Nuclear Information System (INIS)

    Jardine, L J; Moshkov, M M.

    1999-01-01

    The Advanced Research Workshop (ARW) on Nuclear Materials Safety held June 8-10, 1998, in St. Petersburg, Russia, was attended by 27 Russian experts from 14 different Russian organizations, seven European experts from six different organizations, and 14 U.S. experts from seven different organizations. The ARW was conducted at the State Education Center (SEC), a former Minatom nuclear training center in St. Petersburg. Thirty-three technical presentations were made using simultaneous translations. These presentations are reprinted in this volume as a formal ARW Proceedings in the NATO Science Series. The representative technical papers contained here cover nuclear material safety topics on the storage and disposition of excess plutonium and high enriched uranium (HEU) fissile materials, including vitrification, mixed oxide (MOX) fuel fabrication, plutonium ceramics, reprocessing, geologic disposal, transportation, and Russian regulatory processes. This ARW completed discussions by experts of the nuclear materials safety topics that were not covered in the previous, companion ARW on Nuclear Materials Safety held in Amarillo, Texas, in March 1997. These two workshops, when viewed together as a set, have addressed most nuclear material aspects of the storage and disposition operations required for excess HEU and plutonium. As a result, specific experts in nuclear materials safety have been identified, know each other from their participation in t he two ARW interactions, and have developed a partial consensus and dialogue on the most urgent nuclear materials safety topics to be addressed in a formal bilateral program on t he subject. A strong basis now exists for maintaining and developing a continuing dialogue between Russian, European, and U.S. experts in nuclear materials safety that will improve the safety of future nuclear materials operations in all the countries involved because of t he positive synergistic effects of focusing these diverse backgrounds of

  6. How Symmetrical Assumptions Advance Strategic Management Research

    DEFF Research Database (Denmark)

    Foss, Nicolai Juul; Hallberg, Hallberg

    2014-01-01

    We develop the case for symmetrical assumptions in strategic management theory. Assumptional symmetry obtains when assumptions made about certain actors and their interactions in one of the application domains of a theory are also made about this set of actors and their interactions in other...... application domains of the theory. We argue that assumptional symmetry leads to theoretical advancement by promoting the development of theory with greater falsifiability and stronger ontological grounding. Thus, strategic management theory may be advanced by systematically searching for asymmetrical...

  7. Next Steps: Water Technology Advances (Research)

    Science.gov (United States)

    This project will focus on contaminants and their impact on health, adequate removal of contaminants from various water systems, and water and resource recovery within treatment systems. It will develop the next generation of technological advances to provide guidance in support ...

  8. Proceedings of the 6th symposium on advanced photon research

    International Nuclear Information System (INIS)

    2005-06-01

    The 6th Symposium on Advanced Photon Research was held at JAERI-Kansai in Kyoto on November 4-5, 2004. The symposium has been held once a year since 1999, to promote the advanced photon research through speeches, information exchanges, discussion by researchers on the front line of advanced photon research in Japan and abroad, not only reports of latest research results and plans at Advanced Photon Research Center. The numbers of speeches were 16, including 5 invited speeches, and the numbers of poster presentations were 56, including the report of presentations and cooperative research and joint research performed in FY2003. The 56 of the presented papers are indexed individually. (J.P.N.)

  9. Proceedings of the first symposium on advanced photon research

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This report consists of 76 contributed papers of the First Symposium on Advanced Photon Research, which was held at Keihanna Plaza and JAERI Advanced Photon Research Center in Kyoto on November 8-9, 1999. The numbers of oral presentations including a special invited talk and poster presentations were 14 and 68, respectively. (J.P.N.)

  10. Proceedings of the fourth symposium on advanced photon research

    International Nuclear Information System (INIS)

    2003-07-01

    This report consists of 67 contributed papers of the Fourth Symposium on Advanced Photon Research, which was held at JAERI Advanced Photon Research Center in Kyoto on November 28-29, 2002. The numbers of speeches were 14, including 5 invited speeches, and the numbers of poster presentations were 62, including FY 2001 joint research and cooperative research presentations. The 66 of the presented papers are indexed individually. (J.P.N.)

  11. Participatory action research advances climate change adaptation ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2012-05-01

    May 1, 2012 ... The Application of Participatory Action Research to Climate Change Adaptation in ... Soil fertility management · A series of country case studies ... to 2012 as a joint initiative of Canada's International Development Research ...

  12. Research | Integral geometry and advanced stereology

    DEFF Research Database (Denmark)

    Christensen, Sabrina Tang; Plessis, Andrew du

    2015-01-01

    This contribution to the journal CSGB annual report summarises my research on topology and digital image analysis until 2014.......This contribution to the journal CSGB annual report summarises my research on topology and digital image analysis until 2014....

  13. Research | Integral geometry and advanced stereology

    DEFF Research Database (Denmark)

    Christensen, Sabrina Tang; Plessis, Andrew du

    2014-01-01

    This contribution to the journal CSGB annual report summarises my research on topology and digital image analysis until 2013.......This contribution to the journal CSGB annual report summarises my research on topology and digital image analysis until 2013....

  14. Advanced Radioisotope Power Systems Segmented Thermoelectric Research

    Science.gov (United States)

    Caillat, Thierry

    2004-01-01

    Flight times are long; - Need power systems with >15 years life. Mass is at an absolute premium; - Need power systems with high specific power and scalability. 3 orders of magnitude reduction in solar irradiance from Earth to Pluto. Nuclear power sources preferable. The Overall objective is to develop low mass, high efficiency, low-cost Advanced Radioisotope Power System with double the Specific Power and Efficiency over state-of-the-art Radioisotope Thermoelectric Generators (RTGs).

  15. Research overview: Advanced Manufacturing in Switzerland

    OpenAIRE

    Schärer, Claudia

    2016-01-01

    SATW is convinced that industrial production methods will see fundamental changes over the coming years. Mastering new production technologies (advanced manufacturing) such as additive manufacturing and industry 4.0 will be vital to keep Swiss production at a competitive level. New additive manufacturing processes such as 3D printing offer revolutionary opportunities and have the potential to replace traditional production methods. Industry 4.0 has seen the definition of a new concept for...

  16. Advanced Pediatric Brain Imaging Research Program

    Science.gov (United States)

    2016-10-01

    pediatric magnetic resonance imaging ( MRI ) techniques are revolutionizing our understanding of brain injury, its potential for recovery, and...training program, advanced MRI , brain injury. 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER OF PAGES 19a. NAME OF RESPONSIBLE...is located at www.MilitaryMedED.com. The site can be accessed from any device web browser (personal computer, tablet or phone) and operating system

  17. Technical advances in rhinologic basic science research.

    Science.gov (United States)

    Ramanathan, Murugappan; Turner, Justin H; Lane, Andrew P

    2009-10-01

    Chronic rhinosinusitis (CRS) is the single most common self-reported chronic health condition in the United States and is estimated to affect 16% of the adult population annually. Despite the prevalence of this disease, there still exists an incomplete understanding of CRS pathophysiology. In this review, the authors highlight technological advances in rhinology: real-time polymerase chain reaction, epithelial cell culture, flow cytometry, genomics/single-nucleotide polymorphism detection, microarrays, and genetic/nongenetic animal models of sinusitis. The purpose of this review is to describe these methodologies and their contributions toward achieving a better understanding of CRS.

  18. Special Education Research Advances Knowledge in Education

    Science.gov (United States)

    Vaughn, Sharon; Swanson, Elizabeth A.

    2015-01-01

    Research in special education has yielded beneficial outcomes for students with disabilities as well as typical achieving students. The authors provide examples of the valuable knowledge special education research has generated, including the elements of response to intervention (e.g., screening and progress monitoring), instructional practices…

  19. Beyond competence: advance directives in dementia research

    NARCIS (Netherlands)

    K.R. Jongsma (Karin); S. van de Vathorst (Suzanne)

    2015-01-01

    textabstractDementia is highly prevalent and incurable. The participation of dementia patients in clinical research is indispensable if we want to find an effective treatment for dementia. However, one of the primary challenges in dementia research is the patients’ gradual loss of the capacity to

  20. The Role of Research in Advanced Dental Education.

    Science.gov (United States)

    Profitt, William R.; Vig, Peter S.

    1980-01-01

    Even though research is an integral part of quality advanced dental programs, many dental departments with postdoctoral programs lack faculty and other resources for research productivity. Programs to produce clinical faculty with research training are called for through the development of clinical research centers. (JSR)

  1. Environmental research at the Advanced Photon Source

    International Nuclear Information System (INIS)

    Kemner, K.M.; Boyanov, M.I.; Eng, P.; Fenter, P.; Heald, S.; Lai, B.; Lee, S.S.; Scheckel, K.G.; Skanthakumar, S.; Sutton, S.R.; Wilson, R.E.

    2010-01-01

    Because of the importance of probing molecular-scale chemical and physical structure of environmental samples in their natural and often hydrated state, synchrotron radiation has been a powerful tool for environmental scientists for decades. Thus, the crucial role that a highly coherent and high-brightness hard X-ray source such as the Advance Photon Source (APS) can play in addressing many of the outstanding questions in molecular environmental science (MES) was recognized even before 'first light' at the facility. No single synchrotron-based technique or experimental approach can adequately address the tremendous temporal and spatial heterogeneities of the chemistry, physics, and biology of natural environmental samples. Thus, it is common at the APS that multiple X-ray techniques and experimental systems are employed to investigate environmental samples, often chosen for their ability to focus on solute species, plants, microbes, organics, interfacial species, or solids.

  2. Advancing Global Cancer Research @ AACR 2015

    Science.gov (United States)

    Research Priorities for NCI’s Center for Global Health' and included presentations on our mission, objectives, currently funded programs, and future programs given by Dr. Lisa Stevens and Paul Pearlman, as well as three special presentations by NCI grantees.

  3. Strategic decisions on research for advanced reactors: USNRS perspective

    International Nuclear Information System (INIS)

    Johnson, M.

    2008-01-01

    This document provided a perspective on strategic decision on research for advanced reactors. He pointed out that advanced reactors are fundamentally different from LWR and that regulatory tools currently available (e.g. codes and data) will not be applicable to advanced designs. He stated that international co-operation is the only practical way to work together for identifying needed capabilities and tools, including the use of industry facilities. He proposed that, in consideration of its good experience at coordinating research, the CSNI establishes a task group to identify and prioritize research needs. (author)

  4. Conceptualizing and Advancing Research Networking Systems

    Science.gov (United States)

    SCHLEYER, TITUS; BUTLER, BRIAN S.; SONG, MEI; SPALLEK, HEIKO

    2013-01-01

    Science in general, and biomedical research in particular, is becoming more collaborative. As a result, collaboration with the right individuals, teams, and institutions is increasingly crucial for scientific progress. We propose Research Networking Systems (RNS) as a new type of system designed to help scientists identify and choose collaborators, and suggest a corresponding research agenda. The research agenda covers four areas: foundations, presentation, architecture, and evaluation. Foundations includes project-, institution- and discipline-specific motivational factors; the role of social networks; and impression formation based on information beyond expertise and interests. Presentation addresses representing expertise in a comprehensive and up-to-date manner; the role of controlled vocabularies and folksonomies; the tension between seekers’ need for comprehensive information and potential collaborators’ desire to control how they are seen by others; and the need to support serendipitous discovery of collaborative opportunities. Architecture considers aggregation and synthesis of information from multiple sources, social system interoperability, and integration with the user’s primary work context. Lastly, evaluation focuses on assessment of collaboration decisions, measurement of user-specific costs and benefits, and how the large-scale impact of RNS could be evaluated with longitudinal and naturalistic methods. We hope that this article stimulates the human-computer interaction, computer-supported cooperative work, and related communities to pursue a broad and comprehensive agenda for developing research networking systems. PMID:24376309

  5. Conceptualizing and Advancing Research Networking Systems.

    Science.gov (United States)

    Schleyer, Titus; Butler, Brian S; Song, Mei; Spallek, Heiko

    2012-03-01

    Science in general, and biomedical research in particular, is becoming more collaborative. As a result, collaboration with the right individuals, teams, and institutions is increasingly crucial for scientific progress. We propose Research Networking Systems (RNS) as a new type of system designed to help scientists identify and choose collaborators, and suggest a corresponding research agenda. The research agenda covers four areas: foundations, presentation, architecture , and evaluation . Foundations includes project-, institution- and discipline-specific motivational factors; the role of social networks; and impression formation based on information beyond expertise and interests. Presentation addresses representing expertise in a comprehensive and up-to-date manner; the role of controlled vocabularies and folksonomies; the tension between seekers' need for comprehensive information and potential collaborators' desire to control how they are seen by others; and the need to support serendipitous discovery of collaborative opportunities. Architecture considers aggregation and synthesis of information from multiple sources, social system interoperability, and integration with the user's primary work context. Lastly, evaluation focuses on assessment of collaboration decisions, measurement of user-specific costs and benefits, and how the large-scale impact of RNS could be evaluated with longitudinal and naturalistic methods. We hope that this article stimulates the human-computer interaction, computer-supported cooperative work, and related communities to pursue a broad and comprehensive agenda for developing research networking systems.

  6. Advanced nuclear reactor safety issues and research needs

    International Nuclear Information System (INIS)

    2002-01-01

    On 18-20 February 2002, the OECD Nuclear Energy Agency (NEA) organised, with the co-sponsorship of the International Atomic Energy Agency (IAEA) and in collaboration with the European Commission (EC), a Workshop on Advanced Nuclear Reactor Safety Issues and Research Needs. Currently, advanced nuclear reactor projects range from the development of evolutionary and advanced light water reactor (LWR) designs to initial work to develop even further advanced designs which go beyond LWR technology (e.g. high-temperature gas-cooled reactors and liquid metal-cooled reactors). These advanced designs include a greater use of advanced technology and safety features than those employed in currently operating plants or approved designs. The objectives of the workshop were to: - facilitate early identification and resolution of safety issues by developing a consensus among participating countries on the identification of safety issues, the scope of research needed to address these issues and a potential approach to their resolution; - promote the preservation of knowledge and expertise on advanced reactor technology; - provide input to the Generation IV International Forum Technology Road-map. In addition, the workshop tried to link advancement of knowledge and understanding of advanced designs to the regulatory process, with emphasis on building public confidence. It also helped to document current views on advanced reactor safety and technology, thereby contributing to preserving knowledge and expertise before it is lost. (author)

  7. International Journal of Educational Research: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  8. Mtafiti Mwafrika (African Researcher): Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  9. Global Journal of Educational Research: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  10. Nanotechnology: Advancing the translational respiratory research

    OpenAIRE

    Dua, Kamal; Shukla, Shakti Dhar; de Jesus Andreoli Pinto, Terezinha; Hansbro, Philip Michael

    2017-01-01

    Considering the various limitations associated with the conventional dosage forms, nanotechnology is gaining increased attention in drug delivery particularly in respiratory medicine and research because of its advantages like targeting effects, improved pharmacotherapy, and patient compliance. This paper provides a quick snapshot about the recent trends and applications of nanotechnology to various translational and formulation scientists working on various respiratory diseases, which can he...

  11. African Journal of Biomedical Research: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  12. Advanced Energy Projects: FY 1993, Research summaries

    International Nuclear Information System (INIS)

    1993-09-01

    AEP has been supporting research on novel materials for energy technology, renewable and biodegradable materials, new uses for scientific discoveries, alternate pathways to energy efficiency, alternative energy sources, innovative approaches to waste treatment and reduction, etc. The summaries are grouped according to projects active in FY 1993, Phase I SBIR projects, and Phase II SBIR projects. Investigator and institutional indexes are included

  13. Research in Hospitality Management: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  14. Beginnings and advances in heavy ion research

    International Nuclear Information System (INIS)

    Brix, P.

    1979-01-01

    The very important field of heavy ion research is briefly reviewed from the beginnings up to the present time. The article was intended to be a scientific lecture for the general public read on the occasion of the 70th birthday of Prof. Schmelzer. (KBE)

  15. Highland Medical Research Journal: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  16. Nigerian Journal of Technological Research: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  17. Tanzania Journal of Health Research: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  18. Advanced fuel in the Budapest research reactor

    International Nuclear Information System (INIS)

    Hargitai, T.; Vidovsky, I.

    1997-01-01

    The Budapest Research Reactor, the first nuclear facility of Hungary, started to operate in 1959. The main goal of the reactor is to serve neutron research, but applications as neutron radiography, radioisotope production, pressure vessel surveillance test, etc. are important as well. The Budapest Research Reactor is a tank type reactor, moderated and cooled by light water. After a reconstruction and upgrading in 1967 the VVR-SM type fuel elements were used in it. These fuel elements provided a thermal power of 5 MW in the period 1967-1986 and 10 MW after the reconstruction from 1992. In the late eighties the Russian vendor changed the fuel elements slightly, i.e. the main parameters of the fuel remained unchanged, however a higher uranium content was reached. This new fuel is called VVR-M2. The geometry of VVR-SM and VVR-M2 are identical, allowing the use to load old and new fuel assemblies together to the active core. The first new type fuel assemblies were loaded to the Budapest Research Reactor in 1996. The present paper describes the operational experience with the new type of fuel elements in Hungary. (author)

  19. Zimbabwe Journal of Educational Research: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  20. Moor Journal of Agricultural Research: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  1. International Journal of Community Research: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  2. African Journal of AIDS Research: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  3. Tropical Journal of Pharmaceutical Research: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  4. Nigerian Journal of Pharmaceutical Research: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  5. Tropical Journal of Medical Research: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  6. Plant Products Research Journal: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  7. Journal of Business Research: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  8. African Journal of Management Research: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  9. Research Journal of Health Sciences: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  10. Advanced Energy Projects: FY 1993, Research summaries

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    AEP has been supporting research on novel materials for energy technology, renewable and biodegradable materials, new uses for scientific discoveries, alternate pathways to energy efficiency, alternative energy sources, innovative approaches to waste treatment and reduction, etc. The summaries are grouped according to projects active in FY 1993, Phase I SBIR projects, and Phase II SBIR projects. Investigator and institutional indexes are included.

  11. Global Journal of Engineering Research: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  12. Advances in Bayesian Modeling in Educational Research

    Science.gov (United States)

    Levy, Roy

    2016-01-01

    In this article, I provide a conceptually oriented overview of Bayesian approaches to statistical inference and contrast them with frequentist approaches that currently dominate conventional practice in educational research. The features and advantages of Bayesian approaches are illustrated with examples spanning several statistical modeling…

  13. Advances in Music-Reading Research

    Science.gov (United States)

    Gudmundsdottir, Helga Rut

    2010-01-01

    The purpose of this paper is to construct a comprehensive review of the research literature in the reading of western staff notation. Studies in music perception, music cognition, music education and music neurology are cited. The aim is to establish current knowledge in music-reading acquisition and what is needed for further progress in this…

  14. Advances in insect physiology. Progress in mosquito research

    Science.gov (United States)

    This book review briefly summarizes the most interesting topics/chapters from the book: "Advances in Insect Physiology: Progress in mosquito Research". The book is an excellent overview of the recent advances in mosquito biology. This volume encompasses 13 chapters from 32 contributing authors who ...

  15. Advancing translational research with the Semantic Web.

    Science.gov (United States)

    Ruttenberg, Alan; Clark, Tim; Bug, William; Samwald, Matthias; Bodenreider, Olivier; Chen, Helen; Doherty, Donald; Forsberg, Kerstin; Gao, Yong; Kashyap, Vipul; Kinoshita, June; Luciano, Joanne; Marshall, M Scott; Ogbuji, Chimezie; Rees, Jonathan; Stephens, Susie; Wong, Gwendolyn T; Wu, Elizabeth; Zaccagnini, Davide; Hongsermeier, Tonya; Neumann, Eric; Herman, Ivan; Cheung, Kei-Hoi

    2007-05-09

    A fundamental goal of the U.S. National Institute of Health (NIH) "Roadmap" is to strengthen Translational Research, defined as the movement of discoveries in basic research to application at the clinical level. A significant barrier to translational research is the lack of uniformly structured data across related biomedical domains. The Semantic Web is an extension of the current Web that enables navigation and meaningful use of digital resources by automatic processes. It is based on common formats that support aggregation and integration of data drawn from diverse sources. A variety of technologies have been built on this foundation that, together, support identifying, representing, and reasoning across a wide range of biomedical data. The Semantic Web Health Care and Life Sciences Interest Group (HCLSIG), set up within the framework of the World Wide Web Consortium, was launched to explore the application of these technologies in a variety of areas. Subgroups focus on making biomedical data available in RDF, working with biomedical ontologies, prototyping clinical decision support systems, working on drug safety and efficacy communication, and supporting disease researchers navigating and annotating the large amount of potentially relevant literature. We present a scenario that shows the value of the information environment the Semantic Web can support for aiding neuroscience researchers. We then report on several projects by members of the HCLSIG, in the process illustrating the range of Semantic Web technologies that have applications in areas of biomedicine. Semantic Web technologies present both promise and challenges. Current tools and standards are already adequate to implement components of the bench-to-bedside vision. On the other hand, these technologies are young. Gaps in standards and implementations still exist and adoption is limited by typical problems with early technology, such as the need for a critical mass of practitioners and installed base

  16. Advancing gut microbiome research using cultivation

    DEFF Research Database (Denmark)

    Sommer, Morten OA

    2015-01-01

    Culture-independent approaches have driven the field of microbiome research and illuminated intricate relationships between the gut microbiota and human health. However, definitively associating phenotypes to specific strains or elucidating physiological interactions is challenging for metagenomic...... approaches. Recently a number of new approaches to gut microbiota cultivation have emerged through the integration of high-throughput phylogenetic mapping and new simplified cultivation methods. These methodologies are described along with their potential use within microbiome research. Deployment of novel...... cultivation approaches should enable improved studies of xenobiotic tolerance and modification phenotypes and allow a drastic expansion of the gut microbiota reference genome catalogues. Furthermore, the new cultivation methods should facilitate systematic studies of the causal relationship between...

  17. Microfluidic Devices in Advanced Caenorhabditis elegans Research

    Directory of Open Access Journals (Sweden)

    Muniesh Muthaiyan Shanmugam

    2016-08-01

    Full Text Available The study of model organisms is very important in view of their potential for application to human therapeutic uses. One such model organism is the nematode worm, Caenorhabditis elegans. As a nematode, C. elegans have ~65% similarity with human disease genes and, therefore, studies on C. elegans can be translated to human, as well as, C. elegans can be used in the study of different types of parasitic worms that infect other living organisms. In the past decade, many efforts have been undertaken to establish interdisciplinary research collaborations between biologists, physicists and engineers in order to develop microfluidic devices to study the biology of C. elegans. Microfluidic devices with the power to manipulate and detect bio-samples, regents or biomolecules in micro-scale environments can well fulfill the requirement to handle worms under proper laboratory conditions, thereby significantly increasing research productivity and knowledge. The recent development of different kinds of microfluidic devices with ultra-high throughput platforms has enabled researchers to carry out worm population studies. Microfluidic devices primarily comprises of chambers, channels and valves, wherein worms can be cultured, immobilized, imaged, etc. Microfluidic devices have been adapted to study various worm behaviors, including that deepen our understanding of neuromuscular connectivity and functions. This review will provide a clear account of the vital involvement of microfluidic devices in worm biology.

  18. The United States Advanced Reactor Technologies Research and Development Program

    International Nuclear Information System (INIS)

    O’Connor, Thomas J.

    2014-01-01

    The following aspects are addressed: • Nuclear energy mission; • Reactor research development and deployment (RD&D) programs: - Light Water Reactor Sustainability Program; - Small Modular Reactor Licensing Technical Support; - Advanced Reactor Technologies (ART)

  19. Research and development of advanced materials using ion beam

    Energy Technology Data Exchange (ETDEWEB)

    Namba, Susumu [Nagasaki Inst. of Applied Science, Nagasaki (Japan)

    1997-03-01

    A wide range of research and development activities of advanced material synthesis using ion beams will be discussed, including ion beam applications to the state-of-the-art electronics from giant to nano electronics. (author)

  20. Advancing prion science: guidance for the National Prion Research Program

    National Research Council Canada - National Science Library

    Erdtmann, Rick; Sivitz, Laura

    2004-01-01

    In Advancing Prion Science , the Institute of Medicine’s Committee on Transmissible Spongiform Encephalopathies Assessment of Relevant Science recommends priorities for research and investment to the Department of Defenseâ...

  1. Institute for Advanced Learning and Research names new executive director

    OpenAIRE

    Virginia Tech News

    2008-01-01

    Virginia Tech's Institute for Advanced Learning and Research has named Liam E. Leightley as executive director, effective Oct. 6, 2008, according to Mike Henderson, chair of the institute's board of trustees.

  2. Advancing translational research with the Semantic Web

    Science.gov (United States)

    Ruttenberg, Alan; Clark, Tim; Bug, William; Samwald, Matthias; Bodenreider, Olivier; Chen, Helen; Doherty, Donald; Forsberg, Kerstin; Gao, Yong; Kashyap, Vipul; Kinoshita, June; Luciano, Joanne; Marshall, M Scott; Ogbuji, Chimezie; Rees, Jonathan; Stephens, Susie; Wong, Gwendolyn T; Wu, Elizabeth; Zaccagnini, Davide; Hongsermeier, Tonya; Neumann, Eric; Herman, Ivan; Cheung, Kei-Hoi

    2007-01-01

    Background A fundamental goal of the U.S. National Institute of Health (NIH) "Roadmap" is to strengthen Translational Research, defined as the movement of discoveries in basic research to application at the clinical level. A significant barrier to translational research is the lack of uniformly structured data across related biomedical domains. The Semantic Web is an extension of the current Web that enables navigation and meaningful use of digital resources by automatic processes. It is based on common formats that support aggregation and integration of data drawn from diverse sources. A variety of technologies have been built on this foundation that, together, support identifying, representing, and reasoning across a wide range of biomedical data. The Semantic Web Health Care and Life Sciences Interest Group (HCLSIG), set up within the framework of the World Wide Web Consortium, was launched to explore the application of these technologies in a variety of areas. Subgroups focus on making biomedical data available in RDF, working with biomedical ontologies, prototyping clinical decision support systems, working on drug safety and efficacy communication, and supporting disease researchers navigating and annotating the large amount of potentially relevant literature. Results We present a scenario that shows the value of the information environment the Semantic Web can support for aiding neuroscience researchers. We then report on several projects by members of the HCLSIG, in the process illustrating the range of Semantic Web technologies that have applications in areas of biomedicine. Conclusion Semantic Web technologies present both promise and challenges. Current tools and standards are already adequate to implement components of the bench-to-bedside vision. On the other hand, these technologies are young. Gaps in standards and implementations still exist and adoption is limited by typical problems with early technology, such as the need for a critical mass of

  3. Advancing translational research with the Semantic Web

    Directory of Open Access Journals (Sweden)

    Marshall M Scott

    2007-05-01

    Full Text Available Abstract Background A fundamental goal of the U.S. National Institute of Health (NIH "Roadmap" is to strengthen Translational Research, defined as the movement of discoveries in basic research to application at the clinical level. A significant barrier to translational research is the lack of uniformly structured data across related biomedical domains. The Semantic Web is an extension of the current Web that enables navigation and meaningful use of digital resources by automatic processes. It is based on common formats that support aggregation and integration of data drawn from diverse sources. A variety of technologies have been built on this foundation that, together, support identifying, representing, and reasoning across a wide range of biomedical data. The Semantic Web Health Care and Life Sciences Interest Group (HCLSIG, set up within the framework of the World Wide Web Consortium, was launched to explore the application of these technologies in a variety of areas. Subgroups focus on making biomedical data available in RDF, working with biomedical ontologies, prototyping clinical decision support systems, working on drug safety and efficacy communication, and supporting disease researchers navigating and annotating the large amount of potentially relevant literature. Results We present a scenario that shows the value of the information environment the Semantic Web can support for aiding neuroscience researchers. We then report on several projects by members of the HCLSIG, in the process illustrating the range of Semantic Web technologies that have applications in areas of biomedicine. Conclusion Semantic Web technologies present both promise and challenges. Current tools and standards are already adequate to implement components of the bench-to-bedside vision. On the other hand, these technologies are young. Gaps in standards and implementations still exist and adoption is limited by typical problems with early technology, such as the need

  4. Defense Department funds advanced military wireless networks research

    OpenAIRE

    Crumbley, Liz

    2005-01-01

    The U.S. Department of Defense has awarded a $246,000 Defense University Research Instrumentation Program (DURIP) grant to researchers in Virginia Tech's Bradley Department of Electrical and Computer Engineering for advanced research on wireless communications networks that are critical during military maneuvers.

  5. Strategy to Promote Active Learning of an Advanced Research Method

    Science.gov (United States)

    McDermott, Hilary J.; Dovey, Terence M.

    2013-01-01

    Research methods courses aim to equip students with the knowledge and skills required for research yet seldom include practical aspects of assessment. This reflective practitioner report describes and evaluates an innovative approach to teaching and assessing advanced qualitative research methods to final-year psychology undergraduate students. An…

  6. Advanced ASON prototyping research activities in China

    Science.gov (United States)

    Hu, WeiSheng; Jin, Yaohui; Guo, Wei; Su, Yikai; He, Hao; Sun, Weiqiang

    2005-02-01

    This paper provides an overview of prototyping research activities of automatically switched optical networks and transport networks (ASONs/ASTNs) in China. In recent years, China has recognized the importance and benefits of the emerging ASON/ASTN techniques. During the period of 2001 and 2002, the national 863 Program of China started the preliminary ASON research projects with the main objectives to build preliminary ASON testbeds, develop control plane protocols and test their performance in the testbeds. During the period of 2003 and 2004, the 863 program started ASTN prototyping equipment projects for more practical applications. Totally 12 ASTN equipments are being developed by three groups led by Chinese venders: ZTE with Beijing University of Posts and Telecommunications (BUPT), Wuhan Research Institute of Posts and Telecommunication (WRI) with Shanghai Jiao Tong University (SJTU), and Huawei Inc. Meanwhile, as the ASTN is maturing, some of the China"s carries are participating in the OIF"s World Interoperability Demonstration, carrying out ASTN test, or deploying ASTN backbone networks. Finally, several ASTN backbone networks being tested or deployed now will be operated by the carries in 2005. The 863 Program will carry out an ASTN field trail in Yangtse River Delta, and finally deploy the 3TNET. 3TNET stands for Tbps transmission, Tbps switching, and Tbps routing, as well as a network integrating the above techniques. A task force under the "863" program is responsible for ASTN equipment specifications and interoperation agreements, technical coordination among all the participants, schedule of the whole project during the project undergoing, and organization of internetworking of all the equipments in the laboratories and field trials.

  7. Advanced Research Workshop on Nonlinear Hyperbolic Problems

    CERN Document Server

    Serre, Denis; Raviart, Pierre-Arnaud

    1987-01-01

    The field of nonlinear hyperbolic problems has been expanding very fast over the past few years, and has applications - actual and potential - in aerodynamics, multifluid flows, combustion, detonics amongst other. The difficulties that arise in application are of theoretical as well as numerical nature. In fact, the papers in this volume of proceedings deal to a greater extent with theoretical problems emerging in the resolution of nonlinear hyperbolic systems than with numerical methods. The volume provides an excellent up-to-date review of the current research trends in this area.

  8. Advances in lactoferrin research concerning bovine mastitis.

    Science.gov (United States)

    Shimazaki, Kei-Ichi; Kawai, Kazuhiro

    2017-02-01

    Lactoferrin is a multifunctional, iron-binding glycoprotein found in milk and other exocrine secretions. Lactoferrin in milk plays vital roles in the healthy development of newborn mammals, and is also an innate resistance factor involved in the prevention of mammary gland infection by microorganisms. Inflammation of the udder because of bacterial infection is referred to as mastitis. There have been many investigations into the relationships between lactoferrin and mastitis, which fall into several categories. The main categories are fluctuations in the lactoferrin concentration of milk, lactoferrin activity against mastitis pathogens, elucidation of the processes underlying the onset of mastitis, participation of lactoferrin in the immune system, and utilization of lactoferrin in mastitis treatment and prevention. This minireview describes lactoferrin research concerning bovine mastitis. In the 1970s, many researchers reported that the lactoferrin concentration fluctuates in milk from cows with mastitis. From the late 1980s, many studies clarified the infection-defense mechanism in the udder and the contribution of lactoferrin to the immune system. After the year 2000, the processes underlying the onset of mastitis were elucidated in vivo and in vitro, and lactoferrin was applied for the treatment and prevention of mastitis.

  9. Connectomics in psychiatric research: advances and applications

    Directory of Open Access Journals (Sweden)

    Cao M

    2015-10-01

    Full Text Available Miao Cao,* Zhijiang Wang,* Yong He State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, People’s Republic of China *These authors contributed equally to this work Abstract: Psychiatric disorders disturb higher cognitive functions and severely compromise human health. However, the pathophysiological mechanisms underlying psychiatric disorders are very complex, and understanding these mechanisms remains a great challenge. Currently, many psychiatric disorders are hypothesized to reflect “faulty wiring” or aberrant connectivity in the brains. Imaging connectomics is arising as a promising methodological framework for describing the structural and functional connectivity patterns of the human brain. Recently, alterations of brain networks in the connectome have been reported in various psychiatric disorders, and these alterations may provide biomarkers for disease diagnosis and prognosis for the evaluation of treatment efficacy. Here, we summarize the current achievements in both the structural and functional connectomes in several major psychiatric disorders (eg, schizophrenia, attention-deficit/hyperactivity disorder, and autism based on multi-modal neuroimaging data. We highlight the current progress in the identification of these alterations and the hypotheses concerning the aberrant brain networks in individuals with psychiatric disorders and discuss the research questions that might contribute to a further mechanistic understanding of these disorders from a connectomic perspective.Keywords: psychiatric disorders, connectome, graph theory, functional connectivity, structural connectivity

  10. Research on geothermal chemistry and advanced instrumentation

    Science.gov (United States)

    Robertus, R. J.; Shannon, D. W.; Sullivan, R. G.; Kindle, C. H.; Pool, K. H.

    1985-09-01

    Research at the Pacific Northwest Laboratory (PNL) focuses on long-term geothermal power plant reliability. Past work concentrated on development of continuous high-temperature probes for monitoring process variables. PNL also completed a comprehensive handbook of brine treatment processes as they relate to injection well longevity. A recently completed study analyzed corrosion in the hydrocarbon system of a binary cycle plant. Over the two-year monitoring period, corrosion rates were less than 1 MPY in any part of the hydrocarbon system. The system was kept completely dry so the rates seem reasonable. Present projects include: (1) determination of gas breakout conditions at the Herber Binary Demonstration Plant operated by San Diego Gas and Electric Company; (2) generation of water mixing solubility data; (3) installation of prototype leak detectors at the Herber Plant; and (4) evaluation of state-of-the-art particle counters.

  11. INEEL Advanced Radiotherapy Research Program Annual Report 2001

    International Nuclear Information System (INIS)

    Venhuizen, James R.

    2002-01-01

    This report summarizes the major activities and accomplishments of the Idaho National Engineering and Environmental Laboratory (INEEL) Advanced Radiotherapy Research Program for calendar year 2001. Applications of supportive research and development, as well as technology deployment in the fields of chemistry, radiation physics and dosimetry, and neutron source design and demonstration are described. Contributions in the fields of physics and biophysics include development of advanced patient treatment planning software, feasibility studies of accelerator neutron source technology for Neutron Capture Therapy (NCT), and completion of major modifications to the research reactor at Washington State University to produce an epithermal-neutron beam for NCT research applications

  12. INEEL Advanced Radiotherapy Research Program Annual Report 2001

    Energy Technology Data Exchange (ETDEWEB)

    Venhuizen, James Robert

    2002-04-01

    This report summarizes the major activities and accomplishments of the Idaho National Engineering and Environmental Laboratory (INEEL) Advanced Radiotherapy Research Program for calendar year 2001. Applications of supportive research and development, as well as technology deployment in the fields of chemistry, radiation physics and dosimetry, and neutron source design and demonstration are described. Contributions in the fields of physics and biophysics include development of advanced patient treatment planning software, feasibility studies of accelerator neutron source technology for Neutron Capture Therapy (NCT), and completion of major modifications to the research reactor at Washington State University to produce an epithermal-neutron beam for NCT research applications.

  13. INEEL Advanced Radiotherapy Research Program Annual Report 2001

    Energy Technology Data Exchange (ETDEWEB)

    Venhuizen, James R.

    2002-04-30

    This report summarizes the major activities and accomplishments of the Idaho National Engineering and Environmental Laboratory (INEEL) Advanced Radiotherapy Research Program for calendar year 2001. Applications of supportive research and development, as well as technology deployment in the fields of chemistry, radiation physics and dosimetry, and neutron source design and demonstration are described. Contributions in the fields of physics and biophysics include development of advanced patient treatment planning software, feasibility studies of accelerator neutron source technology for Neutron Capture Therapy (NCT), and completion of major modifications to the research reactor at Washington State University to produce an epithermal-neutron beam for NCT research applications.

  14. Research advancements in palm oil nutrition*

    Science.gov (United States)

    May, Choo Yuen; Nesaretnam, Kalanithi

    2014-01-01

    Palm oil is the major oil produced, with annual world production in excess of 50 million tonnes. About 85% of global palm oil produced is used in food applications. Over the past three decades, research on nutritional benefits of palm oil have demonstrated the nutritional adequacy of palm oil and its products, and have resulted in transitions in the understanding these attributes. Numerous studies have demonstrated that palm oil was similar to unsaturated oils with regards to effects on blood lipids. Palm oil provides a healthy alternative to trans-fatty acid containing hydrogenated fats that have been demonstrated to have serious deleterious effects on health. The similar effects of palm oil on blood lipids, comparable to other vegetable oils could very well be due to the structure of the major triglycerides in palm oil, which has an unsaturated fatty acid in the stereospecific numbers (sn)-2 position of the glycerol backbone. In addition, palm oil is well endowed with a bouquet of phytonutrients beneficial to health, such as tocotrienols, carotenoids, and phytosterols. This review will provide an overview of studies that have established palm oil as a balanced and nutritious oil. PMID:25821404

  15. Research advancements in palm oil nutrition.

    Science.gov (United States)

    May, Choo Yuen; Nesaretnam, Kalanithi

    2014-10-01

    Palm oil is the major oil produced, with annual world production in excess of 50 million tonnes. About 85% of global palm oil produced is used in food applications. Over the past three decades, research on nutritional benefits of palm oil have demonstrated the nutritional adequacy of palm oil and its products, and have resulted in transitions in the understanding these attributes. Numerous studies have demonstrated that palm oil was similar to unsaturated oils with regards to effects on blood lipids. Palm oil provides a healthy alternative to trans-fatty acid containing hydrogenated fats that have been demonstrated to have serious deleterious effects on health. The similar effects of palm oil on blood lipids, comparable to other vegetable oils could very well be due to the structure of the major triglycerides in palm oil, which has an unsaturated fatty acid in the stereospecific numbers ( sn) -2 position of the glycerol backbone. In addition, palm oil is well endowed with a bouquet of phytonutrients beneficial to health, such as tocotrienols, carotenoids, and phytosterols. This review will provide an overview of studies that have established palm oil as a balanced and nutritious oil.

  16. Diterpenes: Advances in Neurobiological Drug Research.

    Science.gov (United States)

    Islam, Md Torequl; da Silva, Claucenira Bandeira; de Alencar, Marcus Vinícius Oliveira Barros; Paz, Márcia Fernanda Correia Jardim; Almeida, Fernanda Regina de Castro; Melo-Cavalcante, Ana Amélia de Carvalho

    2016-06-01

    A significant number of studies have been performed with diterpene effect on the brain. Our study aims to make a systematic revision on them. The initial purpose of this review was to screen diterpenes with neurological activity, in particular those that have already been studied and published in different journals (databases until August 2015). The second purpose was to make an action-wise discussion as results viewed on them by taking into drug discovery and development account. Diterpenes considered in this review were selected on the basis of updated information on them and having sufficient information on their screenings. We identified several examples of diterpenes having an interest in further study. We have included the possible sources of them as observed in evidence, their known molecular neurobiological mechanisms, and the active constituents responsible for such activities with the doses and test systems. Results suggest diterpenes to have neurobiological activities like neuro-protection, anti-epileptic, anxiolytic, anti-Alzheimer's disease, anti-Parkinson's disease, anti-cerebral ischemia, anti-neuropathic pain, anti-neuro-inflammatory, and many more. In conclusion, diterpenes may be the prominent candidates in neurobiological drug research. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  17. Advancing the Science of Qualitative Research to Promote Health Equity.

    Science.gov (United States)

    Griffith, Derek M; Shelton, Rachel C; Kegler, Michelle

    2017-10-01

    Qualitative methods have long been a part of health education research, but how qualitative approaches advance health equity has not been well described. Qualitative research is an increasingly important methodologic tool to use in efforts to understand, inform, and advance health equity. Qualitative research provides critical insight into the subjective meaning and context of health that can be essential for understanding where and how to intervene to inform health equity research and practice. We describe the larger context for this special theme issue of Health Education & Behavior, provide brief overviews of the 15 articles that comprise the issue, and discuss the promise of qualitative research that seeks to contextualize and illuminate answers to research questions in efforts to promote health equity. We highlight the critical role that qualitative research can play in considering and incorporating a diverse array of contextual information that is difficult to capture in quantitative research.

  18. Cooperative research for human factors review of advanced control rooms

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jung Woon; Park, Jae Chang; Lee, Yong Hee; Oh, In Seok; Lee, Hyun Chul

    2000-12-01

    This project has been performed as cooperative research between KAERI and USNRC. Human factors issues related to soft controls, which is one of key features of advanced HSI, are identified in this project. The issues are analyzed for the evaluation approaches in either experimental or analytical ways. Also, issues requiring additional researches for the evaluation of advanced HSI are identified in the areas of advanced information systems design, computer-based procedure systems, soft controls, human systems interface and plant modernization process, and maintainability of digital systems. The issues are analyzed to discriminate the urgency of researches on it to high, medium, and low levels in consideration of advanced HSI development status in Korea, and some of the issues that can be handled by experimental researches are identified. Additionally, an experimental study is performed to compare operator's performance on human error detection in advanced control rooms vs. in conventional control rooms. It is found that advanced control rooms have several design characteristics hindering operator's error detection performance compared to conventional control rooms.

  19. Cooperative research for human factors review of advanced control rooms

    International Nuclear Information System (INIS)

    Lee, Jung Woon; Park, Jae Chang; Lee, Yong Hee; Oh, In Seok; Lee, Hyun Chul

    2000-12-01

    This project has been performed as cooperative research between KAERI and USNRC. Human factors issues related to soft controls, which is one of key features of advanced HSI, are identified in this project. The issues are analyzed for the evaluation approaches in either experimental or analytical ways. Also, issues requiring additional researches for the evaluation of advanced HSI are identified in the areas of advanced information systems design, computer-based procedure systems, soft controls, human systems interface and plant modernization process, and maintainability of digital systems. The issues are analyzed to discriminate the urgency of researches on it to high, medium, and low levels in consideration of advanced HSI development status in Korea, and some of the issues that can be handled by experimental researches are identified. Additionally, an experimental study is performed to compare operator's performance on human error detection in advanced control rooms vs. in conventional control rooms. It is found that advanced control rooms have several design characteristics hindering operator's error detection performance compared to conventional control rooms

  20. Recent advances in aerosol research a bibliographical review

    CERN Document Server

    Davies, C N

    1964-01-01

    Recent Advances in Aerosol Research: A Bibliographical Review presents a bibliographic review of advances in aerosol research covering the period from the beginning of 1957 to the end of 1962. Topics covered include chemical reactions, combustion, coagulation and diffusion, and adhesion of particles. References on filtration, evaporation and condensation, nucleation and growth, and laminar flow and impingement are also included. This volume is comprised of 19 chapters and begins by citing research on acoustic, ultrasonic, and shock wave effects, along with adhesion of particles, chemical react

  1. Proceedings of national symposium on advanced instrumentation for nuclear research

    International Nuclear Information System (INIS)

    1993-01-01

    The National Symposium on Advanced Instrumentation for Nuclear Research was held in Bombay during January 27-29, 1993 at BARC. Progress of modern nuclear research is closely related to the availability of state of the art instruments and systems. With the advancements in experimental techniques and sophisticated detector developments, the performance specifications have become more stringent. State of the art techniques and diverse applications of sophisticated nuclear instrumentation systems are discussed along with indigenous efforts to meet the specific instrumentation needs of research programs in nuclear sciences. Papers of relevance to nuclear science and technology are indexed separately. (original)

  2. Proceedings of the 1st symposium on advanced science research

    International Nuclear Information System (INIS)

    1995-09-01

    The 1st symposium on advanced science research was held in Tokai-mura, Ibaraki-ken, on 23-24 March, 1995, under the auspices of JAERI. Two hundred and sixty scientists attended the symposium; over 40% of the attendants were from universities and laboratories outside JAERI. This proceedings consists of 6 oral presentations of the research activities in the Advanced Science Research Center, 70 poster presentations on the field of basic science from both the inside and outside of JAERI and 2 panel discussions on the actinide physics and biocrystallography. (author)

  3. NATO Advanced Research Institute on the Efficiency of Manufacturing Systems

    CERN Document Server

    Berg, C; French, D

    1983-01-01

    The Advanced Research Institute (A.R. 1.) on "the efficiency of Manufacturing Systems" was held under the auspices of the NATO Special Programm~ Panel on Systems Science as a part of the NATO Science Committee's continuous effort to promote the advancement of science through international co-operation. Advanced Research Institutes are organised for the purpose of bringing together experts in a particular field of interest to identify and make known the present state of knowledge in that area and, through informed debate, to make recommendations for directions for future research that would benefit the community at large. To this end two kinds of contribution were obtained by invitation. There were those papers which were about the current state of work in the area of manufacturing systems and its organisation; in addition three theme papers were presented to provide a stimulus to the discussion in terms of ways of thinking, both about the area and about the kind of research needed.

  4. Establishment of Research Infrastructure for National Advanced Radiation Technology

    Energy Technology Data Exchange (ETDEWEB)

    Kuk, Il Hiun; Byun, Myung Woo; Jeong, Il Yun; and others

    2007-07-15

    Construction of fundamental analysis system for RT/RFT advancement and pilot scale laboratory/facility for industry support and Assembly/installation of 30 MeV cyclotron for RI production and research utilizing positron beam, and construction of /distribution system for industrial and medical purpose were carried out for fast settlement for research environment of ARTI (a Jeongeup branch of KAERI)

  5. Advanced Research Projects Agency on Materials Preparation and Characterization Research

    Science.gov (United States)

    Briefly summarized is research concerned with such topics as: Preparation of silica glass from amorphous silica; Glass structure by Raman ...ferroelectrics; Silver iodide crystals; Vapor phase growth; Refractory optical host materials; Hydroxyapatite ; Calcite; Characterization of single crystals with a double crystal spectrometer; Characterization of residual strain.

  6. Research advances in regorafenib in treatment of hepatocellular carcinoma

    Directory of Open Access Journals (Sweden)

    CHEN Weibo

    2017-12-01

    Full Text Available Hepatocellular carcinoma (HCC is the most common malignant liver tumor, and there are limited systemic treatments for patients with advanced HCC. Regorafenib is an oral multi-kinase inhibitor, and phase III clinical trial has shown that regorafenib can significantly extend the median survival of patients with advanced HCC by 2.8 months, which makes it a second-line drug approved by FDA for the treatment of advanced HCC, just after sorafenib. This article reviews the basic and clinical research on regorafenib in the field of HCC.

  7. Proceedings of the fifth symposium on advanced photon research

    International Nuclear Information System (INIS)

    2004-06-01

    This report consists of 69 contributed papers of the Fifth Symposium on Advanced Photon Research, which was held at JAERI-Kansai in Kyoto on November 20-21, 2003. The numbers of speeches were 14, including 4 invited speeches, and the numbers of poster presentations were 60, including FY2002 and cooperative research and joint research presentations. The 69 of the presented papers are indexed individually. (J.P.N.)

  8. Physics of thin films advances in research and development

    CERN Document Server

    Hass, Georg; Vossen, John L

    2013-01-01

    Physics of Thin Films: Advances in Research and Development, Volume 12 reviews advances that have been made in research and development concerning the physics of thin films. This volume covers a wide range of preparative approaches, physics phenomena, and applications related to thin films. This book is comprised of four chapters and begins with a discussion on metal coatings and protective layers for front surface mirrors used at various angles of incidence from the ultraviolet to the far infrared. Thin-film materials and deposition conditions suitable for minimizing reflectance changes with

  9. Storytelling to access social context and advance health equity research.

    Science.gov (United States)

    Banks, JoAnne

    2012-11-01

    Increased understanding of individual and social determinants of health is crucial to moving toward health equity. This essay examines storytelling as a vehicle for advancing health equity research. Contemplative examination of storytelling as a research strategy. An overview of story theory is provided. This is followed by an examination of storytelling as a tool for increasing understanding about the contexts in which people negotiate health, strengthening participation of communities in addressing health issues, and building bridges between researchers and target populations. Storytelling can be a powerful tool for advancing health equity research. However, its effective use requires a renegotiation of relationships between researchers and target communities, as well as setting aside routine time to attend storytelling events and read a variety of stories. Copyright © 2011 Elsevier Inc. All rights reserved.

  10. 2017 Publications Demonstrate Advancements in Wind Energy Research

    Energy Technology Data Exchange (ETDEWEB)

    2018-01-17

    In 2017, wind energy experts at the National Renewable Energy Laboratory (NREL) made significant strides to advance wind energy. Many of these achievements were presented in articles published in scientific and engineering journals and technical reports that detailed research accomplishments in new and progressing wind energy technologies. During fiscal year 2017, NREL wind energy thought leaders shared knowledge and insights through 45 journal articles and 25 technical reports, benefiting academic and national-lab research communities; industry stakeholders; and local, state, and federal decision makers. Such publications serve as important outreach, informing the public of how NREL wind research, analysis, and deployment activities complement advanced energy growth in the United States and around the world. The publications also illustrate some of the noteworthy outcomes of U.S. Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) and Laboratory Directed Research and Development funding, as well as funding and facilities leveraged through strategic partnerships and other collaborations.

  11. Advancing a Program of Research within a Nursing Faculty Role

    Science.gov (United States)

    Nolan, Marie T.; Wenzel, Jennifer; Han, Hae-Ra.; Allen, Jerilyn K.; Paez, Kathryn A.; Mock, Victoria

    2008-01-01

    Doctoral students and new faculty members often seek advice from more senior faculty on how to advance their program of research. Students may ask whether they should choose the manuscript option for their dissertation or whether they should seek a postdoctoral fellowship. New faculty members wonder whether they should pursue a career development (K) award and whether they need a mentor as they strive to advance their research while carrying out teaching, service, and practice responsibilities. In this paper, we describe literature on the impact of selected aspects of pre and postdoctoral training and faculty strategies on scholarly productivity in the faculty role. We also combine our experiences at a school of nursing within a research-intensive university to suggest strategies for success. Noting the scarcity of research that evaluates the effect of these strategies we are actively engaged in collecting data on their relationship to the scholarly productivity of students and faculty members within our own institution. PMID:19022210

  12. Proceedings of the 10th symposium on advanced photon research

    International Nuclear Information System (INIS)

    2010-06-01

    The 10th Symposium on Advanced Photon Research was held at Kansai Photon Science Institute, Japan Atomic Energy Agency (JAEA-KPSI) in Kizugawa, Kyoto on October 21 - 22, 2009. This report consists of invited and contributed papers presented at the oral and poster sessions in the Symposium. The 38 of the presented papers are indexed individually. (J.P.N.)

  13. INL Advanced Radiotherapy Research Program Annual Report 2004

    Energy Technology Data Exchange (ETDEWEB)

    James Venhuizen

    2005-06-01

    This report summarizes the activities and major accomplishments for the Idaho National Laboratory Advanced Radiotherapy Research Program for calendar year 2004. Topics covered include boron analysis in biological samples, computational dosimetry and treatment planning software development, medical neutron source development and characterization, and collaborative dosimetry studies at the RA-1 facility in Buenos Aires, Argentina.

  14. Proceedings of the 13th symposium on advanced photon research

    International Nuclear Information System (INIS)

    2013-09-01

    The 13th Symposium on Advanced Photon Research was held at Kansai Photon Science Institute, Japan Atomic Energy Agency (JAEA-KPSI) in Kizugawa-shi, Kyoto on November 15 - 16, 2012. This report consists of invited and contributed papers presented at the oral and poster sessions in the Symposium. (author)

  15. INEEL Advanced Radiotherapy Research Program Annual Report for 2002

    Energy Technology Data Exchange (ETDEWEB)

    J. R. Venhuizen

    2003-05-01

    This report summarizes the activities and major accomplishments for the Idaho National Engineering and Environmental Laboratory (INEEL) Advanced Radiotherapy Research Program for calendar year 2002. Topics covered include computational dosimetry and treatment planning software development, medical neutron source development and characterization, and boron analytical chemistry.

  16. INEEL Advanced Radiotherapy Research Program Annual Report 2002

    Energy Technology Data Exchange (ETDEWEB)

    Venhuizen, J.R.

    2003-05-23

    This report summarizes the activities and major accomplishments for the Idaho National Engineering and Environmental Laboratory (INEEL) Advanced Radiotherapy Research Program for calendar year 2002. Topics covered include computational dosimetry and treatment planning software development, medical neutron source development and characterization, and boron analytical chemistry.

  17. Defining Neighborhood Boundaries for Social Measurement: Advancing Social Work Research

    Science.gov (United States)

    Foster, Kirk A.; Hipp, J. Aaron

    2011-01-01

    Much of the current neighborhood-based research uses variables aggregated on administrative boundaries such as zip codes, census tracts, and block groups. However, other methods using current technological advances in geographic sciences may broaden our ability to explore the spatial concentration of neighborhood factors affecting individuals and…

  18. Proceedings of the 9th symposium on advanced photon research

    International Nuclear Information System (INIS)

    2010-03-01

    The 9th Symposium on Advanced Photon Research was held at Kansai Photon Science Institute, Japan Atomic Energy Agency (JAEA-KPSI) in Kizugawa, Kyoto on July 31- August 1, 2008. This report consists of invited and contributed papers presented at the oral and poster sessions in The Symposium. The 25 of the presented papers are indexed individually. (J.P.N.)

  19. Proceedings of the 11th symposium on advanced photon research

    International Nuclear Information System (INIS)

    2011-03-01

    The 11th Symposium on Advanced Photon Research was held at Kansai Photon Science Institute, Japan Atomic Energy Agency (JAEA-KPSI) in Kizugawa, Kyoto on June 24 - 25, 2010. This report consists of invited and contributed papers presented at the oral and poster sessions in the Symposium. The 29 of the presented papers are indexed individually. (J.P.N.)

  20. Advancing multilevel thinking and methods in HRM research

    NARCIS (Netherlands)

    Renkema, Maarten; Meijerink, Jeroen Gerard; Bondarouk, Tatiana

    2016-01-01

    Purpose Despite the growing belief that multilevel research is necessary to advance HRM understanding, there remains a lack of multilevel thinking – the application of principles for multilevel theory building. The purpose of this paper is to propose a systematic approach for multilevel HRM

  1. [The advances of suppression in research of amblyopia].

    Science.gov (United States)

    Liu, S; Liu, H

    2016-04-11

    Suppression that is the result of interocular competition is an important machanism of amblyopia. The imbalance of suppression may lead the consequence to amblyopia. In the early study, researchers had raised the theory of II. Quadratic Summation which had revealed the relationship of interocular interaction and suppression. In some basic researches, other studies had showed the most possible anatomic location of suppression. Recently, researchers found a new method to quantify the interocular suppression named the noise model. Further studies found a novel disinhibition therapy to treat amblyopia. We summarized the research advances in suppression and disinhibition treatment in amblyopia. (Chin J Ophthalmol, 2016, 52: 305-308).

  2. Ninth International Symposium on Recent Advances in Environmental Health Research

    Directory of Open Access Journals (Sweden)

    Paul B. Tchounwou

    2014-01-01

    Full Text Available This special issue of International Journal of Environmental Research and Public Health is dedicated to the publication of selected papers presented at the Eighth International Symposium on Recent Advances in Environmental Health Research. The Symposium was organized by Jackson State University (JSU from 16–19 September, 2012 at the Marriott Hotel in Jackson, Mississippi, USA. It was built upon the overwhelming success of seven previous symposia hosted by JSU.

  3. Eighth International Symposium on Recent Advances in Environmental Health Research

    Directory of Open Access Journals (Sweden)

    Paul B. Tchounwou

    2012-05-01

    Full Text Available This special issue of International Journal of Environmental Research and Public Health is dedicated to the publication of selected papers presented at the Eighth International Symposium on Recent Advances in Environmental Health Research. The Symposium was organized by Jackson State University (JSU from September 18-21, 2011 at the Marriott Hotel in Jackson, Mississippi. It was built upon the overwhelming success of seven previous symposia hosted by JSU. [...

  4. NATO Advanced Research Workshop on Physical Properties of Nano systems

    CERN Document Server

    Bonca, Janez

    2011-01-01

    Recent advances in nanoscience have demonstrated that fundamentally new physical phenomena are found when systems are reduced to sizes comparable to the fundamental microscopic length scales of the material investigated. There has been great interest in this research due, in particular, to its role in the development of spintronics, molecular electronics and quantum information processing. The contributions to this volume describe new advances in many of these fundamental and fascinating areas of nanophysics, including carbon nanotubes, graphene, magnetic nanostructures, transport through coupled quantum dots, spintronics, molecular electronics, and quantum information processing.

  5. Activities of the Research Institute for Advanced Computer Science

    Science.gov (United States)

    Oliger, Joseph

    1994-01-01

    The Research Institute for Advanced Computer Science (RIACS) was established by the Universities Space Research Association (USRA) at the NASA Ames Research Center (ARC) on June 6, 1983. RIACS is privately operated by USRA, a consortium of universities with research programs in the aerospace sciences, under contract with NASA. The primary mission of RIACS is to provide research and expertise in computer science and scientific computing to support the scientific missions of NASA ARC. The research carried out at RIACS must change its emphasis from year to year in response to NASA ARC's changing needs and technological opportunities. Research at RIACS is currently being done in the following areas: (1) parallel computing; (2) advanced methods for scientific computing; (3) high performance networks; and (4) learning systems. RIACS technical reports are usually preprints of manuscripts that have been submitted to research journals or conference proceedings. A list of these reports for the period January 1, 1994 through December 31, 1994 is in the Reports and Abstracts section of this report.

  6. Advancing nursing science through health trajectory research: an introduction.

    Science.gov (United States)

    Wyman, Jean F; Henly, Susan J

    2011-01-01

    The Minnesota Center for Health Trajectory Research has focused on developing ways to better understand how interventions influence health trajectories during transitional, acute, or chronic health challenges across the life span. The health trajectory perspective advances nursing science by providing a person-centered point of view that emphasizes change in health over time within individuals, families, groups, or communities. Theoretical considerations and statistical modeling approaches used in studying health trajectories, along with exemplars from nursing research studies from this special issue of Nursing Research, are highlighted.

  7. A new facility for advanced rocket propulsion research

    Science.gov (United States)

    Zoeckler, Joseph G.; Green, James M.; Raitano, Paul

    1993-06-01

    A new test facility was constructed at the NASA Lewis Research Center Rocket Laboratory for the purpose of conducting rocket propulsion research at up to 8.9 kN (2000 lbf) thrust, using liquid oxygen and gaseous hydrogen propellants. A laser room adjacent to the test cell provides access to the rocket engine for advanced laser diagnostic systems. The size and location of the test cell provide the ability to conduct large amounts of testing in short time periods, with rapid turnover between programs. These capabilities make the new test facility an important asset for basic and applied rocket propulsion research.

  8. Cost/Benefit Prioritization for Advanced Safeguards Research and Development

    International Nuclear Information System (INIS)

    DeMuth, S.F.; Adeli, R.; Thomas, K.E.

    2008-01-01

    A system level study utilizing commercially available Extend TM software, has been initiated to perform cost/benefit analyses for advanced safeguards research and development. The methodology is focused on estimating standard error in the inventory difference (SEID) for reprocessing and fuel fabrication facilities, for various proposed advanced safeguards measurement technologies. The inventory duration, and consequent number of inventories per year, is dictated by the detection of a significant quantity of special nuclear material (SNM). Detection is limited by the cumulative measurement uncertainty for the entire system. The cost of inventories is then compared with the cost of advanced instrumentation and/or process design changes. Current progress includes development of the methodology, future efforts will be focused on ascertaining estimated costs and performance. Case studies will be provided as examples of the methodology. (author)

  9. Advancing the research agenda for diagnostic error reduction.

    Science.gov (United States)

    Zwaan, Laura; Schiff, Gordon D; Singh, Hardeep

    2013-10-01

    Diagnostic errors remain an underemphasised and understudied area of patient safety research. We briefly summarise the methods that have been used to conduct research on epidemiology, contributing factors and interventions related to diagnostic error and outline directions for future research. Research methods that have studied epidemiology of diagnostic error provide some estimate on diagnostic error rates. However, there appears to be a large variability in the reported rates due to the heterogeneity of definitions and study methods used. Thus, future methods should focus on obtaining more precise estimates in different settings of care. This would lay the foundation for measuring error rates over time to evaluate improvements. Research methods have studied contributing factors for diagnostic error in both naturalistic and experimental settings. Both approaches have revealed important and complementary information. Newer conceptual models from outside healthcare are needed to advance the depth and rigour of analysis of systems and cognitive insights of causes of error. While the literature has suggested many potentially fruitful interventions for reducing diagnostic errors, most have not been systematically evaluated and/or widely implemented in practice. Research is needed to study promising intervention areas such as enhanced patient involvement in diagnosis, improving diagnosis through the use of electronic tools and identification and reduction of specific diagnostic process 'pitfalls' (eg, failure to conduct appropriate diagnostic evaluation of a breast lump after a 'normal' mammogram). The last decade of research on diagnostic error has made promising steps and laid a foundation for more rigorous methods to advance the field.

  10. Advances in Statistical Methods for Substance Abuse Prevention Research

    Science.gov (United States)

    MacKinnon, David P.; Lockwood, Chondra M.

    2010-01-01

    The paper describes advances in statistical methods for prevention research with a particular focus on substance abuse prevention. Standard analysis methods are extended to the typical research designs and characteristics of the data collected in prevention research. Prevention research often includes longitudinal measurement, clustering of data in units such as schools or clinics, missing data, and categorical as well as continuous outcome variables. Statistical methods to handle these features of prevention data are outlined. Developments in mediation, moderation, and implementation analysis allow for the extraction of more detailed information from a prevention study. Advancements in the interpretation of prevention research results include more widespread calculation of effect size and statistical power, the use of confidence intervals as well as hypothesis testing, detailed causal analysis of research findings, and meta-analysis. The increased availability of statistical software has contributed greatly to the use of new methods in prevention research. It is likely that the Internet will continue to stimulate the development and application of new methods. PMID:12940467

  11. [Activities of Research Institute for Advanced Computer Science

    Science.gov (United States)

    Gross, Anthony R. (Technical Monitor); Leiner, Barry M.

    2001-01-01

    The Research Institute for Advanced Computer Science (RIACS) carries out basic research and technology development in computer science, in support of the National Aeronautics and Space Administrations missions. RIACS is located at the NASA Ames Research Center, Moffett Field, California. RIACS research focuses on the three cornerstones of IT research necessary to meet the future challenges of NASA missions: 1. Automated Reasoning for Autonomous Systems Techniques are being developed enabling spacecraft that will be self-guiding and self-correcting to the extent that they will require little or no human intervention. Such craft will be equipped to independently solve problems as they arise, and fulfill their missions with minimum direction from Earth. 2. Human-Centered Computing Many NASA missions require synergy between humans and computers, with sophisticated computational aids amplifying human cognitive and perceptual abilities. 3. High Performance Computing and Networking Advances in the performance of computing and networking continue to have major impact on a variety of NASA endeavors, ranging from modeling and simulation to analysis of large scientific datasets to collaborative engineering, planning and execution. In addition, RIACS collaborates with NASA scientists to apply IT research to a variety of NASA application domains. RIACS also engages in other activities, such as workshops, seminars, visiting scientist programs and student summer programs, designed to encourage and facilitate collaboration between the university and NASA IT research communities.

  12. Advancing Alzheimer's research: A review of big data promises.

    Science.gov (United States)

    Zhang, Rui; Simon, Gyorgy; Yu, Fang

    2017-10-01

    To review the current state of science using big data to advance Alzheimer's disease (AD) research and practice. In particular, we analyzed the types of research foci addressed, corresponding methods employed and study findings reported using big data in AD. Systematic review was conducted for articles published in PubMed from January 1, 2010 through December 31, 2015. Keywords with AD and big data analytics were used for literature retrieval. Articles were reviewed and included if they met the eligibility criteria. Thirty-eight articles were included in this review. They can be categorized into seven research foci: diagnosing AD or mild cognitive impairment (MCI) (n=10), predicting MCI to AD conversion (n=13), stratifying risks for AD (n=5), mining the literature for knowledge discovery (n=4), predicting AD progression (n=2), describing clinical care for persons with AD (n=3), and understanding the relationship between cognition and AD (n=3). The most commonly used datasets are AD Neuroimaging Initiative (ADNI) (n=16), electronic health records (EHR) (n=11), MEDLINE (n=3), and other research datasets (n=8). Logistic regression (n=9) and support vector machine (n=8) are the most used methods for data analysis. Big data are increasingly used to address AD-related research questions. While existing research datasets are frequently used, other datasets such as EHR data provide a unique, yet under-utilized opportunity for advancing AD research. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Advances in thermoelectric materials research: Looking back and moving forward.

    Science.gov (United States)

    He, Jian; Tritt, Terry M

    2017-09-29

    High-performance thermoelectric materials lie at the heart of thermoelectrics, the simplest technology applicable to direct thermal-to-electrical energy conversion. In its recent 60-year history, the field of thermoelectric materials research has stalled several times, but each time it was rejuvenated by new paradigms. This article reviews several potentially paradigm-changing mechanisms enabled by defects, size effects, critical phenomena, anharmonicity, and the spin degree of freedom. These mechanisms decouple the otherwise adversely interdependent physical quantities toward higher material performance. We also briefly discuss a number of promising materials, advanced material synthesis and preparation techniques, and new opportunities. The renewable energy landscape will be reshaped if the current trend in thermoelectric materials research is sustained into the foreseeable future. Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

  14. NORA project offers unique reactor research and advanced training opportunities

    International Nuclear Information System (INIS)

    1961-01-01

    An international program for reactor research and advanced training for a period of three years has been established in connection with the Norwegian critical assembly NORA. The aim of the project is to determine, through integral experiments, the basic reactor physics data for lattices moderated with light-water, heavy-water or mixtures of heavy and light water, with fuels of different sizes and spacing, three different enrichments and compositions. The objectives, programme, and facilities are described in details

  15. Applied solid state science advances in materials and device research

    CERN Document Server

    Wolfe, Raymond

    2013-01-01

    Applied Solid State Science: Advances in Materials and Device Research, Volume 1 presents articles about junction electroluminescence; metal-insulator-semiconductor (MIS) physics; ion implantation in semiconductors; and electron transport through insulating thin films. The book describes the basic physics of carrier injection; energy transfer and recombination mechanisms; state of the art efficiencies; and future prospects for light emitting diodes. The text then discusses solid state spectroscopy, which is the pair spectra observed in gallium phosphide photoluminescence. The extensive studies

  16. Collaboration in Research and Engineering for Advanced Technology.

    Energy Technology Data Exchange (ETDEWEB)

    Vrieling, P. Douglas [Sandia National Lab. (SNL-CA), Livermore, CA (United States)

    2016-01-01

    SNL/CA proposes the Collaboration in Research and Engineering for Advanced Technology and Education (CREATE) facility to support customer-driven national security mission requirements while demonstrating a fiscally responsible approach to cost-control. SNL/CA realizes that due to the current backlog of capital projects in NNSA that following the normal Line Item process to procure capital funding is unlikely and therefore SNL/CA will be looking at all options including Alternative Financing.

  17. Applied solid state science advances in materials and device research

    CERN Document Server

    Wolfe, Raymond

    2013-01-01

    Applied Solid State Science: Advances in Materials and Device Research, Volume 4 covers articles on single crystal compound semiconductors and complex polycrystalline materials. The book discusses narrow gap semiconductors and solid state batteries. The text then describes the advantages of hot-pressed microcrystalline compacts of oxygen-octahedra ferroelectrics over single crystal materials, as well as heterostructure junction lasers. Solid state physicists, materials scientists, electrical engineers, and graduate students studying the subjects being discussed will find the book invaluable.

  18. Advances in research on poultry and rabbit meat quality

    Directory of Open Access Journals (Sweden)

    Gerolamo Xiccato

    2010-01-01

    Full Text Available Main force and weakness points of poultry and rabbit production chains are presented and meat quality discussed in relation to nutritional and technological issues. An analysis of the most important poultry and rabbit meat quality traits and their major relationships with production factors (genotype, feeding, housing, pre-slaughter handling, slaughtering, and processing is provided. Most recent research advancements are presen- ted in view of the consumer’s demand for healthy and safe products obtained respecting animal welfare.

  19. Fossil Energy Advanced Research and Technology Development Materials Program

    Energy Technology Data Exchange (ETDEWEB)

    Cole, N.C.; Judkins, R.R. (comps.)

    1992-12-01

    Objective of this materials program is to conduct R and D on materials for fossil energy applications with focus on longer-term and generic needs of the various fossil fuel technologies. The projects are organized according to materials research areas: (1) ceramics, (2) new alloys: iron aluminides, advanced austenitics and chromium niobium alloys, and (3) technology development and transfer. Separate abstracts have been prepared.

  20. Advanced High-Level Waste Glass Research and Development Plan

    Energy Technology Data Exchange (ETDEWEB)

    Peeler, David K. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Vienna, John D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Schweiger, Michael J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Fox, Kevin M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-07-01

    The U.S. Department of Energy Office of River Protection (ORP) has implemented an integrated program to increase the loading of Hanford tank wastes in glass while meeting melter lifetime expectancies and process, regulatory, and product quality requirements. The integrated ORP program is focused on providing a technical, science-based foundation from which key decisions can be made regarding the successful operation of the Hanford Tank Waste Treatment and Immobilization Plant (WTP) facilities. The fundamental data stemming from this program will support development of advanced glass formulations, key process control models, and tactical processing strategies to ensure safe and successful operations for both the low-activity waste (LAW) and high-level waste (HLW) vitrification facilities with an appreciation toward reducing overall mission life. The purpose of this advanced HLW glass research and development plan is to identify the near-, mid-, and longer-term research and development activities required to develop and validate advanced HLW glasses and their associated models to support facility operations at WTP, including both direct feed and full pretreatment flowsheets. This plan also integrates technical support of facility operations and waste qualification activities to show the interdependence of these activities with the advanced waste glass (AWG) program to support the full WTP mission. Figure ES-1 shows these key ORP programmatic activities and their interfaces with both WTP facility operations and qualification needs. The plan is a living document that will be updated to reflect key advancements and mission strategy changes. The research outlined here is motivated by the potential for substantial economic benefits (e.g., significant increases in waste throughput and reductions in glass volumes) that will be realized when advancements in glass formulation continue and models supporting facility operations are implemented. Developing and applying advanced

  1. NATO Advanced Research Institute on Health Services Systems

    CERN Document Server

    Werff, Albert; Hirsch, Gary; Barnard, Keith

    1984-01-01

    The Advanced Research Institute on "Health Services Systems" was held under the auspices of the NATO Special Programme Panel on Systems Science as a part of the NATO Science Committee's continuous effort to promote the advancement of science through international cooperation. A special word is said in this respect supra by Pro­ fessor Checkland, Chairman of the Systems Science Panel. The Advanced Research Institute (ARI) was organized for the purpose of bringing together senior scientists to seek a consensus on the assessment of the present state of knowledge on the specific topic of "health services systems" and to present views and recom­ mendations for future health services research directions, which should be of value to both the scientific community and the people in charge of reorienting health services. The conference was structured so as to permit the assembly of a variety of complementary viewpoints through intensive group discussions to be the basis of this final report. Invitees were selected fr...

  2. Advancing HIV research with pregnant women: navigating challenges and opportunities.

    Science.gov (United States)

    Krubiner, Carleigh B; Faden, Ruth R; Cadigan, R Jean; Gilbert, Sappho Z; Henry, Leslie M; Little, Margaret O; Mastroianni, Anna C; Namey, Emily E; Sullivan, Kristen A; Lyerly, Anne D

    2016-09-24

    Concerns about including pregnant women in research have led to a dearth of evidence to guide safe and effective treatment and prevention of HIV in pregnancy. To better understand why these evidence gaps persist and inform guidance for responsible inclusion of pregnant women in the HIV research agenda, we aimed to learn what HIV experts perceive as barriers and constraints to conducting this research. We conducted a series of group and one-on-one consultations with 62 HIV investigators and clinicians to elicit their views and experiences conducting HIV research involving pregnant women. Thematic analysis was used to identify priorities and perceived barriers to HIV research with pregnant women. Experts discussed a breadth of needed research, including safety, efficacy, and appropriate dosing of: newer antiretrovirals for pregnant women, emerging preventive strategies, and treatment for coinfections. Challenges to conducting research on pregnancy and HIV included ethical concerns, such as how to weigh risks and benefits in pregnancy; legal concerns, such as restrictive interpretations of current regulations and liability issues; financial and professional disincentives, including misaligned funder priorities and fear of reputational damage; and analytical and logistical complexities, such as challenges recruiting and retaining pregnant women to sufficiently power analyses. Investigators face numerous challenges to conducting needed HIV research with pregnant women. Advancing such research will require clearer guidance regarding ethical and legal uncertainties; incentives that encourage rather than discourage investigators to undertake such research; and a commitment to earlier development of safety and efficacy data through creative trial designs.

  3. Advanced accelerator and mm-wave structure research at LANL

    Energy Technology Data Exchange (ETDEWEB)

    Simakov, Evgenya Ivanovna [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-06-22

    This document outlines acceleration projects and mm-wave structure research performed at LANL. The motivation for PBG research is described first, with reference to couplers for superconducting accelerators and structures for room-temperature accelerators and W-band TWTs. These topics are then taken up in greater detail: PBG structures and the MIT PBG accelerator; SRF PBG cavities at LANL; X-band PBG cavities at LANL; and W-band PBG TWT at LANL. The presentation concludes by describing other advanced accelerator projects: beam shaping with an Emittance Exchanger, diamond field emitter array cathodes, and additive manufacturing of novel accelerator structures.

  4. Advanced Radioisotope Power Conversion Technology Research and Development

    Science.gov (United States)

    Wong, Wayne A.

    2004-01-01

    NASA's Radioisotope Power Conversion Technology program is developing next generation power conversion technologies that will enable future missions that have requirements that cannot be met by either the ubiquitous photovoltaic systems or by current Radioisotope Power System (RPS) technology. Performance goals of advanced radioisotope power systems include improvement over the state-of-practice General Purpose Heat Source/Radioisotope Thermoelectric Generator by providing significantly higher efficiency to reduce the number of radioisotope fuel modules, and increase specific power (watts/kilogram). Other Advanced RPS goals include safety, long-life, reliability, scalability, multi-mission capability, resistance to radiation, and minimal interference with the scientific payload. NASA has awarded ten contracts in the technology areas of Brayton, Stirling, Thermoelectric, and Thermophotovoltaic power conversion including five development contracts that deal with more mature technologies and five research contracts. The Advanced RPS Systems Assessment Team includes members from NASA GRC, JPL, DOE and Orbital Sciences whose function is to review the technologies being developed under the ten Radioisotope Power Conversion Technology contracts and assess their relevance to NASA's future missions. Presented is an overview of the ten radioisotope power conversion technology contracts and NASA's Advanced RPS Systems Assessment Team.

  5. Research reactor of the future: The advanced neutron source

    International Nuclear Information System (INIS)

    Appleton, B.; West, C.

    1994-01-01

    Agents for cancer detection and treatment, stronger materials, better electronic gadgets, and other consumer and industrial products - these are assured benefits of a research reactor project proposed for Oak Ridge. Just as American companies have again assumed world leadership in producing semiconductor chips as well as cars and trucks, the United States is poised to retake the lead in neutron science by building and operating the $2.9 billion Advanced Neutron Source (ANS) research reactor by the start of the next century. In 1985, the neutron community, led by ORNL researchers, proposed a pioneering project, later called the ANS. Scheduled to begin operation in 2003, the ANS is seen not only as a replacement for the aging HFIR and HFBR but also as the best laboratory in the world for conducting neutron-based research

  6. The advanced neutron source research and development plan

    International Nuclear Information System (INIS)

    Selby, D.L.

    1995-08-01

    The Advanced Neutron Source (ANS) is being designed as a user-oriented neutron research laboratory centered around the most intense continuous beams of thermal and subthermal neutrons in the world (an order of magnitude more intense than beams available from the most advanced existing reactors). The ANS will be built around a new research reactor of 330-MW fission power, producing an unprecedented peak thermal flux of >7 · 10 19 · m -2 · s -1 . Primarily a research facility, the ANS will accommodate more than 1000 academic, industrial, and government researchers each year. They will conduct basic research in all branches of science as well as applied research leading to better understanding of new materials, including high temperature super conductors, plastics, and thin films. Some 48 neutron beam stations will be set up in the ANS beam rooms and the neutron guide hall for neutron scattering and for fundamental and nuclear physics research. There also will be extensive facilities for materials irradiation, isotope production, and analytical chemistry. The top level work breakdown structure (WBS) for the project. As noted in this figure, one component of the project is a research and development (R ampersand D) program (WBS 1.1). This program interfaces with all of the other project level two WBS activities. Because one of the project guidelines is to meet minimum performance goals without relying on new inventions, this R ampersand D activity is not intended to produce new concepts to allow the project to meet minimum performance goals. Instead, the R ampersand D program will focus on the four objectives described

  7. Utilization of MCNP code in the research and design for China advanced research reactor

    International Nuclear Information System (INIS)

    Shen Feng

    2006-01-01

    MCNP, which is the internationalized neutronics code, is used for nuclear research and design in China Advanced Research Reactor (CARR). MCNP is an important neutronics code in the research and design for CARR since many calculation tasks could be undertaken by it. Many nuclear parameters on reactor core, the design and optimization research for many reactor utilizations, much verification for other nuclear calculation code and so on are conducted with help of MCNP. (author)

  8. Advanced nuclear reactor safety design technology research in NPIC

    International Nuclear Information System (INIS)

    Yu, H.

    2014-01-01

    After the Fukushima accident happen, Nuclear Power Plants (NPPs) construction has been suspended in China for a time. Now the new regulatory rule has been proposed that the most advanced safety standard must be adopted for the new NPPs and practical elimination of large fission product release by design during the next five plans period. So the advanced reactor research is developing in China. NPIC is engaging on the ACP1000 and ACP100 (Small Module Reactor) design. The main design character will be introduced in this paper. The Passive Combined with Active (PCWA) design was adopted during the ACP1000 design to reduce the core damage frequency (CDF); the Cavity Injection System (CIS) is design to mitigation the consequence of the severe accident. Advance passive safety system was designed to ensure the long term residual heat removal during the Small Module Reactor (SMR). The SMR will be utilized to be the floating reactors, district heating reactor and so on. Besides, the Science and Technology on Reactor System Design Technology Laboratory (LRSDT) also engaged on the fundamental thermal-hydraulic characteristic research in support of the system validation. (author)

  9. Los Alamos NEP research in advanced plasma thrusters

    Science.gov (United States)

    Schoenberg, Kurt; Gerwin, Richard

    1991-01-01

    Research was initiated in advanced plasma thrusters that capitalizes on lab capabilities in plasma science and technology. The goal of the program was to examine the scaling issues of magnetoplasmadynamic (MPD) thruster performance in support of NASA's MPD thruster development program. The objective was to address multi-megawatt, large scale, quasi-steady state MPD thruster performance. Results to date include a new quasi-steady state operating regime which was obtained at space exploration initiative relevant power levels, that enables direct coaxial gun-MPD comparisons of thruster physics and performance. The radiative losses are neglible. Operation with an applied axial magnetic field shows the same operational stability and exhaust plume uniformity benefits seen in MPD thrusters. Observed gun impedance is in close agreement with the magnetic Bernoulli model predictions. Spatial and temporal measurements of magnetic field, electric field, plasma density, electron temperature, and ion/neutral energy distribution are underway. Model applications to advanced mission logistics are also underway.

  10. Status report on research on advanced fundamental engineering in 1999

    International Nuclear Information System (INIS)

    2000-07-01

    JNC (Japan Nuclear Cycle Development Institute) has been promoting the cooperative research program on advanced fundamental engineering with the Japanese Universities. It is the 5th year of this program on 1999. JNC has been calling for the research themes of utilizing the equipment and facilities of JNC, which must be the leading research for the JNC projects. The expert committee has selected the issues from the applications of the universities; This report includes the list of the researches and individual summaries implemented in 1999, in which total 49 issues are categorized in the three fields, these are, fast breeder reactor, nuclear fuel cycle, and environment technology. The 26 issues are included in the field of fast breeder reactor. Topics in this area are neutron beam technology to measure voids, laser technology to detect failed fuel, ultra-sonic velocity meter to estimate passive cooling characteristics, behavior of sodium coolant in accidents, physics on TRU fuel, and mechanical and/or chemical characteristics on irradiated solid metals, ceramics and liquids. The 9 issues are included in the field of nuclear fuel cycle. Topics in this area are chemical erosion of material, computerized simulation on actinide by molecular orbit model, chemical stability on advanced reprocessing, laser technology to measure fuel particles, decomposition of fluoride oil, advanced dose evaluation. The 9 issues are included in the field of environment technology. Topics in this area are behavior of underground water, radioactivity ecology of plants, biochemical activities of microbes in deep bedrock. The individual report describes the title, related personnel, its time schedule, objectives, facilities, status, and references in the prearranged format. (Tanaka, T.)

  11. Basic research and industrialization of CANDU advanced fuel

    Energy Technology Data Exchange (ETDEWEB)

    Chun, Suk Ho; Park, Joo Hwan; Jun, Ji Su [and others

    2000-04-01

    Wolsong Unit 1 as the first heavy water reactor in Korea has been in service for 17 years since 1983. It would be about the time to prepare a plan for the solution of problems due to aging of the reactor. The aging of CANDU reactor could lead especially to the steam generator cruding and pressure tube sagging and creep and then decreases the operation margin to make some problems on reactor operations and safety. The counterplan could be made in two ways. One is to repair or modify reactor itself. The other is to develop new advanced fuel to increase of CANDU operation margin effectively, so as to compensate the reduced operation margin. Therefore, the first objectives in the present R and D is to develop the CANFLEX-NU (CANDU Flexible fuelling-Natural Uranium) fuel as a CANDU advanced fuel. The second objectives is to develop CANDU advanced fuel bundle to utilize advanced fuel cycles such as recovered uranium, slightly enriched uranium, etc. and so to raise adaptability for change in situation of uranium market. Also, it is to develop CANDU advanced fuel technology which improve uranium utilization to cope with a world-wide imbalance between uranium supply and demand, without significant modification of nuclear reactor design and refuelling strategies. As the implementations to achieve the above R and D goal, the work contents and scope of technology development of CANDU advanced fuel using natural uranium (CANFLEX-NU) are the fuel element/bundle designs, the nuclear design and fuel management analysis, the thermalhydraulic analysis, the safety analysis, fuel fabrication technologies, the out-pile thermalhydraulic test and in-pile irradiation tests performed. At the next, the work scopes and contents of feasibility study of CANDU advanced fuel using recycled uranium (CANFLEX-RU) are the fuel element/bundle designs, the reactor physics analysis, the thermalhydraulic analysis, the basic safety analysis of a CANDU-6 reactor with CANFLEX-RU fuel, the fabrication and

  12. Basic research and industrialization of CANDU advanced fuel

    International Nuclear Information System (INIS)

    Chun, Suk Ho; Park, Joo Hwan; Jun, Ji Su

    2000-04-01

    Wolsong Unit 1 as the first heavy water reactor in Korea has been in service for 17 years since 1983. It would be about the time to prepare a plan for the solution of problems due to aging of the reactor. The aging of CANDU reactor could lead especially to the steam generator cruding and pressure tube sagging and creep and then decreases the operation margin to make some problems on reactor operations and safety. The counterplan could be made in two ways. One is to repair or modify reactor itself. The other is to develop new advanced fuel to increase of CANDU operation margin effectively, so as to compensate the reduced operation margin. Therefore, the first objectives in the present R and D is to develop the CANFLEX-NU (CANDU Flexible fuelling-Natural Uranium) fuel as a CANDU advanced fuel. The second objectives is to develop CANDU advanced fuel bundle to utilize advanced fuel cycles such as recovered uranium, slightly enriched uranium, etc. and so to raise adaptability for change in situation of uranium market. Also, it is to develop CANDU advanced fuel technology which improve uranium utilization to cope with a world-wide imbalance between uranium supply and demand, without significant modification of nuclear reactor design and refuelling strategies. As the implementations to achieve the above R and D goal, the work contents and scope of technology development of CANDU advanced fuel using natural uranium (CANFLEX-NU) are the fuel element/bundle designs, the nuclear design and fuel management analysis, the thermalhydraulic analysis, the safety analysis, fuel fabrication technologies, the out-pile thermalhydraulic test and in-pile irradiation tests performed. At the next, the work scopes and contents of feasibility study of CANDU advanced fuel using recycled uranium (CANFLEX-RU) are the fuel element/bundle designs, the reactor physics analysis, the thermalhydraulic analysis, the basic safety analysis of a CANDU-6 reactor with CANFLEX-RU fuel, the fabrication and

  13. Review of research on advanced computational science in FY2016

    International Nuclear Information System (INIS)

    2017-12-01

    Research on advanced computational science for nuclear applications, based on “Plan to Achieve Medium- to Long-term Objectives of the Japan Atomic Energy Agency (Medium- to Long-term Plan)”, has been performed at Center for Computational Science and e-Systems (CCSE), Japan Atomic Energy Agency. CCSE established the committee consisting of outside experts and authorities which does research evaluation and advices for the assistance of the research and development. This report summarizes the followings. (1) Results of the R and D performed at CCSE in FY 2016 (April 1st, 2016 - March 31st, 2017), (2) Results of the evaluation on the R and D by the committee in FY 2016. (author)

  14. Intensive Research Program on Advances in Nonsmooth Dynamics 2016

    CERN Document Server

    Jeffrey, Mike; Lázaro, J; Olm, Josep

    2017-01-01

    This volume contains extended abstracts outlining selected talks and other selected presentations given by participants throughout the "Intensive Research Program on Advances in Nonsmooth Dynamics 2016", held at the Centre de Recerca Matemàtica (CRM) in Barcelona from February 1st to April 29th, 2016. They include brief research articles reporting new results, descriptions of preliminary work or open problems, and outlines of prominent discussion sessions. The articles are all the result of direct collaborations initiated during the research program. The topic is the theory and applications of Nonsmooth Dynamics. This includes systems involving elements of: impacting, switching, on/off control, hybrid discrete-continuous dynamics, jumps in physical properties, and many others. Applications include: electronics, climate modeling, life sciences, mechanics, ecology, and more. Numerous new results are reported concerning the dimensionality and robustness of nonsmooth models, shadowing variables, numbers of limit...

  15. Seventh International Symposium on Recent Advances in Environmental Health Research

    Directory of Open Access Journals (Sweden)

    Paul B. Tchounwou

    2011-06-01

    Full Text Available This special issue of International Journal of Environmental Research and Public Health is dedicated to the publication of selected papers presented at the Seventh International Symposium on Recent Advances in Environmental Health Research. The Symposium was organized by Jackson State University (JSU from September 12–15, 2010 at the Marriott Hotel in Jackson, Mississippi. It was built upon the overwhelming success of previous symposia hosted by JSU and co-sponsored by the National Institutes of Health (NIH RCMI-Center for Environmental Health, the U.S. Department of Education Title III Graduate Education Program, the U.S. Environmental Protection Agency, the JSU Office of Academic Affairs, and the JSU Office of Research and Federal Relations. [...

  16. Sixth International Symposium on Recent Advances in Environmental Health Research

    Directory of Open Access Journals (Sweden)

    Paul B. Tchounwou

    2010-05-01

    Full Text Available This special issue of International Journal of Environmental Research and Public Health highlights selected papers presented at the Sixth International Symposium on Recent Advances in Environmental Health Research organized by Jackson State University (JSU from September 13−16, 2009 at the Marriott Hotel in Jackson, Mississippi, USA. The Symposium was built upon the overwhelming success of previous symposia hosted by JSU and co-sponsored by the National Institutes of Health (NIH RCMI-Center for Environmental Health, the U.S. Department of Education Title III Graduate Education Program, the U.S. Environmental Protection Agency, the JSU Office of Academic Affairs, and the JSU Office of Research and Federal Relations. [...

  17. Advances in mechanisms, robotics and design education and research

    CERN Document Server

    Schmiedeler, James; Sreenivasan, S; Su, Hai-Jun

    2013-01-01

    This book contains papers on a wide range of topics in the area of kinematics, mechanisms, robotics, and design, addressing new research advances and innovations in design education. The content is divided into  five main categories headed ‘Historical Perspectives’, ‘Kinematics and Mechanisms’, ‘Robotic Systems’, ‘Legged Locomotion’, and ‘Design Engineering Education’. Contributions take the form of survey articles, historical perspectives, commentaries on trends on education or research, original research contributions, and papers on design education.   This volume celebrates the achievements of Professor Kenneth Waldron who has made innumerable and invaluable contributions to these fields in the last fifty years. His leadership and his pioneering work have influenced thousands of people in this discipline.

  18. Review of research on advanced computational science in FY2015

    International Nuclear Information System (INIS)

    2017-01-01

    Research on advanced computational science for nuclear applications, based on 'Plan to Achieve Medium- to Long-term Objectives of the Japan Atomic Energy Agency (Medium- to Long-term Plan)', has been performed at Center for Computational Science and e-Systems (CCSE), Japan Atomic Energy Agency. CCSE established the committee consisting of outside experts and authorities which does research evaluation and advices for the assistance of the research and development. This report summarizes the followings. (1) Results of the R and D performed at CCSE in FY 2015 (April 1st, 2015 - March 31st, 2016), (2) Results of the evaluation on the R and D by the committee in FY 2015 (April 1st, 2015 - March 31st, 2016). (author)

  19. Advancing nuclear technology and research. The advanced test reactor national scientific user facility

    Energy Technology Data Exchange (ETDEWEB)

    Benson, Jeff B; Marshall, Frances M [Idaho National Laboratory, Idaho Falls, ID (United States); Allen, Todd R [Univ. of Wisconsin, Madison, WI (United States)

    2012-03-15

    The Advanced Test Reactor (ATR), at the Idaho National Laboratory (INL), is one of the world's premier test reactors for providing the capability for studying the effects of intense neutron and gamma radiation on reactor materials and fuels. The INL also has several hot cells and other laboratories in which irradiated material can be examined to study material radiation effects. In 2007 the US Department of Energy (DOE) designated the ATR as a National Scientific User Facility (NSUF) to facilitate greater access to the ATR and the associated INL laboratories for material testing research. The mission of the ATR NSUF is to provide access to world-class facilities, thereby facilitating the advancement of nuclear science and technology. Cost free access to the ATR, INL post irradiation examination facilities, and partner facilities is granted based on technical merit to U.S. university-led experiment teams conducting non-proprietary research. Proposals are selected via independent technical peer review and relevance to United States Department of Energy. To increase overall research capability, ATR NSUF seeks to form strategic partnerships with university facilities that add significant nuclear research capability to the ATR NSUF and are accessible to all ATR NSUF users. (author)

  20. Assessment of Research Needs for Advanced Fuel Cells

    Energy Technology Data Exchange (ETDEWEB)

    Penner, S.S.

    1985-11-01

    The DOE Advanced Fuel Cell Working Group (AFCWG) was formed and asked to perform a scientific evaluation of the current status of fuel cells, with emphasis on identification of long-range research that may have a significant impact on the practical utilization of fuel cells in a variety of applications. The AFCWG held six meetings at locations throughout the country where fuel cell research and development are in progress, for presentations by experts on the status of fuel cell research and development efforts, as well as for inputs on research needs. Subsequent discussions by the AFCWG have resulted in the identification of priority research areas that should be explored over the long term in order to advance the design and performance of fuel cells of all types. Surveys describing the salient features of individual fuel cell types are presented in Chapters 2 to 6 and include elaborations of long-term research needs relating to the expeditious introduction of improved fuel cells. The Introduction and the Summary (Chapter 1) were prepared by AFCWG. They were repeatedly revised in response to comments and criticism. The present version represents the closest approach to a consensus that we were able to reach, which should not be interpreted to mean that each member of AFCWG endorses every statement and every unexpressed deletion. The Introduction and Summary always represent a majority view and, occasionally, a unanimous judgment. Chapters 2 to 6 provide background information and carry the names of identified authors. The identified authors of Chapters 2 to 6, rather than AFCWG as a whole, bear full responsibility for the scientific and technical contents of these chapters.

  1. Research on the Academic Benefits of the Advanced Placement Program

    Directory of Open Access Journals (Sweden)

    Russell T. Warne

    2017-01-01

    Full Text Available With more than 3 million participants per year, the Advanced Placement (AP program is one of the most popular programs in the United States for exposing high-achieving high school students to advanced academic content. Sponsored by the College Board, the AP program provides a framework in which high school teachers can teach introductory college-level courses to high school students. These students then take one of 34 standardized tests at the end of the year, and students who score well on their course’s AP test can receive college credit from their university in which they later enroll. Despite the popularity of the AP program, remarkably little independent research has been conducted on the academic benefits of AP. In this article, I summarize the state of knowledge about the academic benefits of AP. Previous research and descriptive data indicate that AP students outperform non-AP students on a variety of academic measures, but many other aspects of the program are poorly understood, partially due to variability across AP subjects. These aspects include the causal impact of AP, which components of the program are most effective in boosting academic achievement, and how students engage with the AP program. I also conclude by making suggestions for researchers to use new methodologies to investigate new scientific and policy questions and new student populations to improve the educational scholars’ and practitioners’ understanding of the AP program.

  2. Research advances on multifocal electroretinogram in primary open angle glaucoma

    Directory of Open Access Journals (Sweden)

    Feng-Fei Mo

    2013-10-01

    Full Text Available Primary open angle glaucoma is a chronic and progressive optic neuropathy. It can lead to serious damage of visual impairment, and it is an important eye disease of blindness. Multifocal electroretinogram is a new way to measure visual electrophysiology. It can measure electroretinogram of the whole visual field of many small parts in a relatively short period of time, and it can reflect the function of regional retina. It has an extremely important value for early diagnosis of primary open angle glaucoma. The research advances on multifocal electroretinogram in diagnosing primary open angle glaucoma were summarized in this paper.

  3. Advances in research and development of mango industry

    Directory of Open Access Journals (Sweden)

    Ian S. E. Bally

    2011-10-01

    Full Text Available World mango production is spread over 100 countries that produce over 34.3 million tons of fruit annually. Eighty percent of this production is based in the top nine producing nations that also consume upward of 90% of their production domestically. One to 2 percent of fruit is traded internationally in to markets in the European Community, USA, Arabian Peninsula and Asia. This paper outlines some of the recent research and development advances in mango breeding and genomics, rootstock development, disease management and harvest technologies that are influencing the production and quality of mango fruit traded domestically and internationally.

  4. Oklahoma State University proposed Advanced Technology Research Center. Environmental Assessment

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    The Department of Energy (DOE) has prepared an Environmental Assessment (EA) evaluating the construction and equipping of the proposed Advanced Technology Research Center (ATRC) at Oklahoma State University (OSU) in Stillwater, Oklahoma. Based on the analysis in the EA, the DOE has determined that the proposed action does not constitute a major federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) of 1969. Therefore, the preparation of an Environmental Impact Statement is not required.

  5. New era of neutron scattering research on advanced materials

    International Nuclear Information System (INIS)

    Ikeda, Susumu

    2001-01-01

    The projects of the next generation of pulsed spallation neutron source are planed in USA, Europe and Japan. They are one order of magnitude more powerful than the most powerful existing neutron source, ISIS in UK. They offer the exciting prospects for the future, and will open the new era of neutron scattering research on advanced materials. The Japanese project is named as the 'Joint project' between JAERI and KEK on high-intensity proton accelerators. The details of the neutron science facility in the 'Joint project' and the sciences to be developed are summarized. (author)

  6. The Polaris Project: Undergraduate Research Catalyzing Advances in Arctic Science

    Science.gov (United States)

    Schade, J. D.; Holmes, R. M.; Natali, S.; Mann, P. J.; Bunn, A. G.; Frey, K. E.

    2017-12-01

    With guidance and sufficient resources, undergraduates can drive the exploration of new research directions, lead high impact scientific products, and effectively communicate the value of science to the public. As mentors, we must recognize the strong contribution undergraduates make to the advancement of scientific understanding and their unique ability and desire to be transdisciplinary and to translate ideas into action. Our job is to be sure students have the resources and tools to successfully explore questions that they care about, not to provide or lead them towards answers we already have. The central goal of the Polaris Project is to advance understanding of climate change in the Arctic through an integrated research, training, and outreach program that has at its heart a research expedition for undergraduates to a remote field station in the Arctic. Our integrative approach to training provides undergraduates with strong intellectual development and they bring fresh perspectives, creativity, and a unique willingness to take risks on new ideas that have an energizing effect on research and outreach. Since the projects inception in summer 2008, we have had >90 undergraduates participate in high-impact field expeditions and outreach activities. Over the years, we have also been fortunate enough to attract an ethnically, racially, and culturally diverse group of students, including students from Puerto Rico, Hispanic-, African- and Native-Americans, members of the LGBT community, and first-generation college students. Most of these students have since pursued graduate degrees in ecology, and many have received NSF fellowships and Fulbright scholarships. One of our major goals is to increase the diversity of the scientific community, and we have been successful in our short-term goal of recruiting and retaining a diverse group of students. The goal of this presentation is to provide a description of the mentoring model at the heart of the Polaris Project

  7. Women's career advancement in organisations: Integrative framework for research

    Directory of Open Access Journals (Sweden)

    Mišić-Andrić Marijana

    2015-01-01

    Full Text Available Contemporary organisations, caught in the middle of global economic and social crisis, are facing different business challenges, having to respond to quick changes in business environment and demographic changes in workforce composed by increasing number of women. Although the number of women in workforce is on the rise, they are still underrepresented in manager positions, especially higher management. This implies that certain barriers are in place which makes difficult for women to develop their careers, especially in reaching manager positions. The aim of this paper is to analyse and present a theoretical framework for further study of professional carrier advancement for women. The paper especially analyse integrative theoretical framework which stresses the equal importance of researching individual factors (personal influence and organisational factors (social inclusion, having in mind how the organisational context can improve or deter women's carrier. The paper presents possible directions for future research based on the analysis of the theoretical framework and especially individual and organisational factors.

  8. European conference on advances in flood research. Vol. 2. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Bronstert, A; Bismuth, C; Menzel, L [eds.

    2000-11-01

    Following concern expressed by several Member States in the 1990's, the EC directorate General of Research and Development (DG XII) has initiated and/or funded a variety of activities in order to improve the scientific basis and to intensify knowledge transfer into practice concerning flood forecasting, risk mitigation, and the impact analysis of environmental change effects. After more then half a decade of research in this field, this conference is aimed to present the results achieved and to highlight the scientific advances. Besides the presentations of the EUROTAS-project results, the contributions are grouped into the following sub-sessions: impact of land use and climate on flooding, flood management and assessment of flood risk, catchment modelling and management systems, and impact of river engineering on flooding conditions. (orig.)

  9. European conference on advances in flood research. Vol. 1. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Bronstert, A; Bismuth, C; Menzel, L [eds.

    2000-11-01

    Following concern expressed by several Member States in the 1990's, the EC directorate General of Research and Development (DG XII) has initiated and/or funded a variety of activities in order to improve the scientific basis and to intensify knowledge transfer into practice concerning flood forecasting, risk mitigation, and the impact analysis of environmental change effects. After more then half a decade of research in this field, this conference is aimed to present the results achieved and to highlight the scientific advances. Besides the presentations of the EUROTAS-project results, the contributions are grouped into the following sub-sessions: impact of land use and climate on flooding, flood management and assessment of flood risk, catchment modelling and management systems, and impact of river engineering on flooding conditions. (orig.)

  10. European conference on advances in flood research. Vol. 1. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Bronstert, A.; Bismuth, C.; Menzel, L. [eds.

    2000-11-01

    Following concern expressed by several Member States in the 1990's, the EC directorate General of Research and Development (DG XII) has initiated and/or funded a variety of activities in order to improve the scientific basis and to intensify knowledge transfer into practice concerning flood forecasting, risk mitigation, and the impact analysis of environmental change effects. After more then half a decade of research in this field, this conference is aimed to present the results achieved and to highlight the scientific advances. Besides the presentations of the EUROTAS-project results, the contributions are grouped into the following sub-sessions: impact of land use and climate on flooding, flood management and assessment of flood risk, catchment modelling and management systems, and impact of river engineering on flooding conditions. (orig.)

  11. European conference on advances in flood research. Vol. 2. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Bronstert, A.; Bismuth, C.; Menzel, L. [eds.

    2000-11-01

    Following concern expressed by several Member States in the 1990's, the EC directorate General of Research and Development (DG XII) has initiated and/or funded a variety of activities in order to improve the scientific basis and to intensify knowledge transfer into practice concerning flood forecasting, risk mitigation, and the impact analysis of environmental change effects. After more then half a decade of research in this field, this conference is aimed to present the results achieved and to highlight the scientific advances. Besides the presentations of the EUROTAS-project results, the contributions are grouped into the following sub-sessions: impact of land use and climate on flooding, flood management and assessment of flood risk, catchment modelling and management systems, and impact of river engineering on flooding conditions. (orig.)

  12. Social work and research in advanced welfare states

    DEFF Research Database (Denmark)

    and North-Western Europe more generally, there are other countries where the public spend on welfare is relatively high. The contributors to this book explore and exemplify ways in which social work and research are distinctive for advanced welfare states. This involves exploring their connection......The aim of this book is to exemplify the ways in which social work and research develop in ‘advanced’ welfare states - countries where public spending is relatively high as a proportion of GNP. While such countries have traditionally been associated with Scandinavian countries in particular...... to professional identities, histories and welfare systems, their associations with academic, theoretical and cultural traditions of collaboration between academic and social work practice, and the distinctive links with community, national policy, governmentality and agency, with respect to forms of knowledge...

  13. Irradiation Facilities of the Takasaki Advanced Radiation Research Institute

    Directory of Open Access Journals (Sweden)

    Satoshi Kurashima

    2017-03-01

    Full Text Available The ion beam facility at the Takasaki Advanced Radiation Research Institute, the National Institutes for Quantum and Radiological Science and Technology, consists of a cyclotron and three electrostatic accelerators, and they are dedicated to studies of materials science and bio-technology. The paper reviews this unique accelerator complex in detail from the viewpoint of its configuration, accelerator specification, typical accelerator, or irradiation technologies and ion beam applications. The institute has also irradiation facilities for electron beams and 60Co gamma-rays and has been leading research and development of radiation chemistry for industrial applications in Japan with the facilities since its establishment. The configuration and utilization of those facilities are outlined as well.

  14. NATO Advanced Research Workshop on Homogeneous and Heterogeneous Photocatalysis

    CERN Document Server

    Serpone, Nick

    1986-01-01

    Ever since the oil crisis of 1973, researchers in various fields of chemistry have proposed various schemes to conserve energy, as well to convert the sun's abundant and limitless supply of energy to produce chemical fuels (e. g. , hydrogen from water, . •. ). The enthusiasm had no previous parallel in the mid-1970's. Unfortunately, despite the several good proposals, the results have proven - in retrospect - somewhat disappointing from an economic viable point of view. The reasons for the meagre results are manyfold not the least of which are the experimental difficulties encountered in storage systems. Moreover, the lack of a concerted, well orchestrated interdisciplinary approach has been significant. By contrast, the chemical advances made in the understanding of the processes involved in such schemes have been phenomenal. A recent book on this issue ( M. Gratzel, Energy Resources through Photochemistry and Catalysis, 1983) is witness to the various efforts and approaches taken by researchers. In the re...

  15. Basic researches for advancement of man-machine systems

    International Nuclear Information System (INIS)

    Yoshikawa, Hidekazu

    1994-01-01

    The historical development of plant instrumentation and control system accompanying the introduction of automation is shown by the example of nuclear power plants. It is explained, and the change in the role of operators in the man-machine system is mentioned. Human errors are the serious problem in various fields, and automation resolves it. But complex systems also caused various disasters due to the relation of men and machines. The problem of human factors in high risk system automation is considered as the heightening of reliability and the reduction of burden on workers by decreasing human participation, and the increase of the risk of large accidents due to the lowering of reliability of human elements and the strengthening of the training of workers. Human model and the framework of human error analysis, the development of the system for man-machine system design and information analysis and evaluation, the significance of physiological index measurement and the perspective of the application, the analysis of the behavior of subjects in the abnormality diagnosis experiment using a plant simulator, and the development to the research on mutual adaptation interface are discussed. In this paper, the problem of human factors in system safety, that technical advancement brings about is examined, and the basic research on the advancement of man-machine systems by the author is reported. (K.I.)

  16. Economic perspectives of the research on advanced therapies

    Directory of Open Access Journals (Sweden)

    Jose María Pamo Larrauri

    2014-11-01

    Full Text Available Since a new advanced therapy medicinal product is discovered until finally allowed its sale in the domestic market, it has to overcome a series of stages. Biomedical research is the first phase, currently its situation is encouraging to the increase in the number of clinical trials in Spain and in the rest of the world, despite the economic situation and the various difficulties that have faced the pharmaceutical laboratories. The next phase consists in obtaining the authorization of marketing of the European Medicines Agency. After authorization, will attempt to set a fair and moderate price for inclusion in the list of health provision of Social Security. A price for a drug that provides added value to health and society, a price that is generated profits for the pharmaceutical companies that hope to make up for the years of work and investment. Commitment to advanced therapy must be clear and forceful, to fund ongoing research projects and encouraging their creation with economic aid

  17. Research Advance on Metasequoia: Applications of New Technology

    Science.gov (United States)

    Leng, Qin; Yang, Hong; Wang, Li

    2010-10-01

    The plant genus Metasequoia Miki, 1941 and its sole living relict species Metasequoia glyptostroboides Hu et Cheng, 1948 have been of special interest for both the public and scientists since 1941 when the genus was established. Due to its unique discovery history (fossils discovered earlier than the living species) and incomparable scientific value in the research of plant evolution and its relationship with environmental and climatic changes, Metasequoia becomes arguably the most comprehensively studied higher plant in both fossil and living forms. This paper summarized recent advance in Metasequoia research by reviewing the research history of Metasequoia and the scientific value of this genus, while paid special attention to the application of new methods and techniques in the research field of Metasequoia in the recent decades. The application of biogeochemical (organic geochemistry and stable isotope) analysis as well as the new and innovated methods of preparing large-sized cuticular membrane from leaves with originally thin and fragile cuticles further secure Metasequoia's super star status for the research of palaeoclimatic reconstruction.

  18. PREFACE: 7th EEIGM International Conference on Advanced Materials Research

    Science.gov (United States)

    Joffe, Roberts

    2013-12-01

    The 7th EEIGM Conference on Advanced Materials Research (AMR 2013) was held at Luleå University of Technology on the 21-22 March 2013 in Luleå, SWEDEN. This conference is intended as a meeting place for researchers involved in the EEIGM programme, in the 'Erasmus Mundus' Advanced Materials Science and Engineering Master programme (AMASE) and the 'Erasmus Mundus' Doctoral Programme in Materials Science and Engineering (DocMASE). This is great opportunity to present their on-going research in the various fields of Materials Science and Engineering, exchange ideas, strengthen co-operation as well as establish new contacts. More than 60 participants representing six countries attended the meeting, in total 26 oral talks and 19 posters were presented during two days. This issue of IOP Conference Series: Materials Science and Engineering presents a selection of articles from EEIGM-7 conference. Following tradition from previous EEIGM conferences, it represents the interdisciplinary nature of Materials Science and Engineering. The papers presented in this issue deal not only with basic research but also with applied problems of materials science. The presented topics include theoretical and experimental investigations on polymer composite materials (synthetic and bio-based), metallic materials and ceramics, as well as nano-materials of different kind. Special thanks should be directed to the senior staff of Division of Materials Science at LTU who agreed to review submitted papers and thus ensured high scientific level of content of this collection of papers. The following colleagues participated in the review process: Professor Lennart Walström, Professor Roberts Joffe, Professor Janis Varna, Associate Professor Marta-Lena Antti, Dr Esa Vuorinen, Professor Aji Mathew, Professor Alexander Soldatov, Dr Andrejs Purpurs, Dr Yvonne Aitomäki, Dr Robert Pederson. Roberts Joffe October 2013, Luleå Conference photograph EEIGM7 conference participants, 22 March 2013 The PDF

  19. Assessment report of research and development activities. Activity: 'Advanced science research' (Pre-review report)

    International Nuclear Information System (INIS)

    2010-11-01

    Japan Atomic Energy Agency (hereinafter referred to as 'JAEA') consulted an assessment committee, 'Evaluation Committee of Research Activities for Advanced Science Research' (hereinafter referred to as 'Committee') for prior assessment of 'Advanced Science Research,' in accordance with 'General Guideline for the Evaluation of Government Research and Development (R and D) Activities' by Cabinet Office, Government of Japan, 'Guideline for Evaluation of R and D in Ministry of Education, Culture, Sports, Science and Technology' and 'Regulation on Conduct for Evaluation of R and D Activities' by JAEA. In response to the JAEA's request, the Committee assessed the research program and activities of the Advanced Science Research Center (hereinafter referred to as 'ASRC') for the period of five years from April 2010. The Committee evaluated the management and the research program of the ASRC based on the explanatory documents prepared by the ASRC and the oral presentations with questions-and-answers by the Director and the research group leaders. This report summarizes the result of the assessment by the Committee with the Committee report attached from page 7. (author)

  20. Assessment report on research and development activities. Activity: 'Advanced science research' (Interim report)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-11-15

    Japan Atomic Energy Agency (hereinafter referred to as 'JAEA') consulted an assessment committee, 'Evaluation Committee of Research Activities for Advanced Science Research' (hereinafter referred to as 'Committee') for interim assessment of 'Advanced Science Research,' in accordance with 'General Guideline for the Evaluation of Government Research and Development (R and D) Activities' by Cabinet Office, Government of Japan, 'Guideline for Evaluation of R and D in Ministry of Education, Culture, Sports, Science and Technology' and 'Regulation on Conduct for Evaluation of R and D Activities' by JAEA. In response to the JAEA's request, the Committee assessed the research programs and activities of the Advanced Science Research Center (hereinafter referred to as 'ASRC') for the period of two years from April 2010. The Committee evaluated the management and the research programs of the ASRC based on the explanatory documents prepared by the ASRC and the oral presentations with questions-and-answers by the Director and the research group leaders. This report summarizes the result of the assessment by the Committee with the Committee report attached from page 7. (author)

  1. Assessment report of research and development activities. Activity: advanced science research' (Interim report)

    International Nuclear Information System (INIS)

    2008-08-01

    Japan Atomic Energy Agency (hereinafter referred to as 'JAEA') consults an assessment committee, 'Evaluation Committee of Research Activities for Advanced Science Research' (hereinafter referred to as 'Committee') for interim assessment of 'Advanced Science Research,' in accordance with General Guideline for the Evaluation of Government Research and Development (R and D) Activities' by Cabinet Office, Government of Japan, 'Guideline for Evaluation of R and D in Ministry of Education, Culture, Sports, Science and Technology' and 'Regulation on Conduct for Evaluation of R and D Activities' by JAEA. In response to the JAEA's request, the Committee assessed the research program of the Advanced Science Research Center (hereinafter referred to as 'ASRC') during the period of two years from October 2005 to September 2007. The Committee evaluated the management and research activities of the ASRC based on the explanatory documents prepared by the ASRC, the oral presentations with questions-and-answers by the Director and the research group leaders, and interviews from group members through on-site visits by the Committee members. One CD-ROM is attached as an appendix. (J.P.N.)

  2. The Advanced Neutron Source research and development plan

    International Nuclear Information System (INIS)

    Selby, D.L.

    1992-01-01

    The Advanced Neutron Source (ANS) is being designed as a user-oriented neutron research laboratory centered around the most intense continuous beams of thermal and subthermal neutrons in the world. The ANS will be built around a new research reactor of ∼ 330 MW fission power, producing an unprecedented peak thermal flux of > 7 x 10 19 M -2 · S -1 . Primarily a research facility, the ANS will accommodate more than 1000 academic, industrial, and government researchers each year. They will conduct basic research in all branches of science-as well as applied research-leading to better understanding of new materials, including high temperature super conductors, plastics, and thin films. Some 48 neutron beam stations will be set up in the ANS beam rooms and the neutron guide hall for neutron scattering and for fundamental and nuclear physics research. There also will be extensive facilities for materials irradiation, isotope production, and analytical chemistry. The R ampersand D program will focus on the four objectives: Address feasibility issues; provide analysis support; evaluate options for improvement in performance beyond minimum requirements; and provide prototype demonstrations for unique facilities. The remainder of this report presents (1) the process by which the R ampersand D activities are controlled and (2) a discussion of the individual tasks that have been identified for the R ampersand D program, including their justification, schedule and costs. The activities discussed in this report will be performed by Martin Marietta Energy Systems, Inc. (MMES) through the Oak Ridge National Laboratory (ORNL) and through subcontracts with industry, universities, and other national laboratories. It should be noted that in general a success path has been assumed for all tasks

  3. Assessment report on research and development activities. Activity: 'Advanced science research' (Interim report)

    International Nuclear Information System (INIS)

    2012-11-01

    Japan Atomic Energy Agency (hereinafter referred to as “JAEA”) consulted an assessment committee, “Evaluation Committee of Research Activities for Advanced Science Research” (hereinafter referred to as “Committee”) for interim assessment of “Advanced Science Research,” in accordance with “General Guideline for the Evaluation of Government Research and Development (R and D) Activities” by Cabinet Office, Government of Japan, “Guideline for Evaluation of R and D in Ministry of Education, Culture, Sports, Science and Technology” and “Regulation on Conduct for Evaluation of R and D Activities” by JAEA. In response to the JAEA's request, the Committee assessed the research programs and activities of the Advanced Science Research Center (hereinafter referred to as “ASRC”) for the period of two years from April 2010. The Committee evaluated the management and the research programs of the ASRC based on the explanatory documents prepared by the ASRC and the oral presentations with questions-and-answers by the Director and the research group leaders. This report summarizes the result of the assessment by the Committee with the Committee report attached from page 7. (author)

  4. Advancing cancer control research in an emerging news media environment.

    Science.gov (United States)

    Smith, Katherine C; Niederdeppe, Jeff; Blake, Kelly D; Cappella, Joseph N

    2013-12-01

    Cancer is both highly feared and highly newsworthy, and there is a robust body of research documenting the content and effects of cancer news coverage on health behaviors and policy. Recent years have witnessed ongoing, transformative shifts in American journalism alongside rapid advances in communication technology and the public information environment. These changes create a pressing need to consider a new set of research questions, sampling strategies, measurement techniques, and theories of media effects to ensure continued relevance and adaptation of communication research to address critical cancer control concerns. This paper begins by briefly reviewing what we know about the role of cancer news in shaping cancer-related beliefs, attitudes, behaviors, and policies. We then outline challenges and opportunities, both theoretical and methodological, posed by the rapidly changing news media environment and the nature of audience engagement. We organize our discussion around three major shifts associated with the emerging news media environment as it relates to health communication: 1) speed and dynamism of news diffusion, 2) increased narrowcasting of media content for specialized audiences, and 3) broadened participation in shaping media content. In so doing, we articulate a set of questions for future theory and research, in an effort to catalyze innovative communication scholarship to improve cancer prevention and control.

  5. PREFACE: 6th EEIGM International Conference on Advanced Materials Research

    Science.gov (United States)

    Horwat, David; Ayadi, Zoubir; Jamart, Brigitte

    2012-02-01

    The 6th EEIGM Conference on Advanced Materials Research (AMR 2011) was held at the European School of Materials Engineering (EEIGM) on the 7-8 November 2011 in Nancy, France. This biennial conference organized by the EEIGM is a wonderful opportunity for all scientists involved in the EEIGM programme, in the 'Erasmus Mundus' Advanced Materials Science and Engineering Master programme (AMASE) and the 'Erasmus Mundus' Doctoral Programme in Materials Science and Engineering (DocMASE), to present their research in the various fields of Materials Science and Engineering. This conference is also open to other universities who have strong links with the EEIGM and provides a forum for the exchange of ideas, co-operation and future orientations by means of regular presentations, posters and a round-table discussion. This edition of the conference included a round-table discussion on composite materials within the Interreg IVA project '+Composite'. Following the publication of the proceedings of AMR 2009 in Volume 5 of this journal, it is with great pleasure that we present this selection of articles to the readers of IOP Conference Series: Materials Science and Engineering. Once again it represents the interdisciplinary nature of Materials Science and Engineering, covering basic and applicative research on organic and composite materials, metallic materials and ceramics, and characterization methods. The editors are indebted to all the reviewers for reviewing the papers at very short notice. Special thanks are offered to the sponsors of the conference including EEIGM-Université de Lorraine, AMASE, DocMASE, Grand Nancy, Ville de Nancy, Region Lorraine, Fédération Jacques Villermaux, Conseil Général de Meurthe et Moselle, Casden and '+Composite'. Zoubir Ayadi, David Horwat and Brigitte Jamart

  6. Research and Development of Protection OPC server for China advanced research reactor digital monitoring system

    International Nuclear Information System (INIS)

    Jia Yuwen; Xu Qiguo

    2012-01-01

    OPC server was developed as I/O driver to communicate the digital monitoring system of China Advanced Research Reactor iFIX and protection system. The framework and working principle of the OPC server were researched, and an effective method was developed to resolve the special communication protocol. After commissioning and testing, the results show that this method is reliable and stable, makes the system easy to configure, and can reduce the complexity of the system. (authors)

  7. FY09 Advanced Instrumentation and Active Interrogation Research for Safeguards

    International Nuclear Information System (INIS)

    Chichester, D.L.; Pozzi, S.A.; Seabury, E.H.; Dolan, J.L.; Flaska, M.; Johnson, J.T.; Watson, S.M.; Wharton, J.

    2009-01-01

    Multiple small-scale projects have been undertaken to investigate advanced instrumentation solutions for safeguard measurement challenges associated with advanced fuel cycle facilities and next-generation fuel reprocessing installations. These activities are in support of the U.S. Department of Energy's Fuel Cycle Research and Development program and its Materials Protection, Accounting, and Control for Transmutation (MPACT) campaign. (1) Work was performed in a collaboration with the University of Michigan (Prof. Sara Pozzi, co-PI) to investigate the use of liquid-scintillator radiation detectors for assaying mixed-oxide (MOX) fuel, to characterize its composition and to develop advanced digital pulse-shape discrimination algorithms for performing time-correlation measurements in the MOX fuel environment. This work included both simulations and experiments and has shown that these techniques may provide a valuable approach for use within advanced safeguard measurement scenarios. (2) Work was conducted in a collaboration with Oak Ridge National Laboratory (Dr. Paul Hausladen, co-PI) to evaluate the strengths and weaknesses of the fast-neutron coded-aperture imaging technique for locating and characterizing fissile material, and as a tool for performing hold-up measurements in fissile material handling facilities. This work involved experiments at Idaho National Laboratory, using MOX fuel and uranium metal, in both passive and active interrogation configurations. A complete analysis has not yet been completed but preliminary results suggest several potential uses for the fast neutron imaging technique. (3) Work was carried out to identify measurement approaches for determining nitric acid concentration in the range of 1-4 M and beyond. This work included laboratory measurements to investigate the suitability of prompt-gamma neutron activation analysis for this measurement and product reviews of other commercial solutions. Ultrasonic density analysis appears to be

  8. NATO Advanced Research Institute on Search Theory and Applications

    CERN Document Server

    Stone, Lawrence

    1980-01-01

    The NATO Advanced Research Institute on Search Theory and Appli­ cations was held at the Hotel Algarve in Praia Da Rocha, Portugal, from March 26 through March 30, 1979, and was sponsored by the NATO Special Programme Panel on Systems Science. There were forty-one participants representing a wide range of backgrounds and interests. The purpose of the institute was to bring together people working in search theory and applications with potential users of search techniques to stimulate the increased application of recent­ ly developed search technology to civilian problems such as search and rescue, mineral exploration, surveillance, and fishing. Con­ versely, it was felt that by exposing search analysts to potential applications and new problems, they would be stimulated to develop new techniques for these applications and problems. The exchange of ideas and problems necessary to accomplish these goals was provided in the meeting workshops. There were three workshops, Search and Rescue, Exploration, and Sur...

  9. Molecular mechanism of sarcopenia and cachexia: recent research advances.

    Science.gov (United States)

    Sakuma, Kunihiro; Aoi, Wataru; Yamaguchi, Akihiko

    2017-06-01

    Skeletal muscle provides a fundamental basis for human function, enabling locomotion and respiration. Muscle loss occurs as a consequence of several chronic diseases (cachexia) and normal aging (sarcopenia). Although many negative regulators (atrogin-1, muscle ring finger-1, nuclear factor-kappaB (NF-κB), myostatin, etc.) have been proposed to enhance protein degradation during both sarcopenia and cachexia, the adaptation of these mediators markedly differs within both conditions. Sarcopenia and cachectic muscles have been demonstrated to be abundant in myostatin-linked molecules. The ubiquitin-proteasome system (UPS) is activated during rapid atrophy model (cancer cachexia), but few mediators of the UPS change during sarcopenia. NF-κB signaling is activated in cachectic, but not in sarcopenic, muscle. Recent studies have indicated the age-related defect of autophagy signaling in skeletal muscle, whereas autophagic activation occurs in cachectic muscle. This review provides recent research advances dealing with molecular mediators modulating muscle mass in both sarcopenia and cachexia.

  10. Design requirement for electrical system of an advanced research reactor

    International Nuclear Information System (INIS)

    Jung, Hoan Sung; Kim, H. K.; Kim, Y. K.; Wu, J. S.; Ryu, J. S.

    2004-12-01

    An advanced research reactor is being designed since 2002 and the conceptual design has been completed this year for the several types of core. Also the fuel was designed for the potential cores. But the process system, the I and C system, and the electrical system design are under pre-conceptual stage. The conceptual design for those systems will be developed in the next year. Design requirements for the electrical system set up to develop conceptual design. The same goals as reactor design - enhance safety, reliability, economy, were applied for the development of the requirements. Also the experience of HANARO design and operation was based on. The design requirements for the power distribution, standby power supply, and raceway system will be used for the conceptual design of electrical system

  11. Design requirement for electrical system of an advanced research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Hoan Sung; Kim, H. K.; Kim, Y. K.; Wu, J. S.; Ryu, J. S

    2004-12-01

    An advanced research reactor is being designed since 2002 and the conceptual design has been completed this year for the several types of core. Also the fuel was designed for the potential cores. But the process system, the I and C system, and the electrical system design are under pre-conceptual stage. The conceptual design for those systems will be developed in the next year. Design requirements for the electrical system set up to develop conceptual design. The same goals as reactor design - enhance safety, reliability, economy, were applied for the development of the requirements. Also the experience of HANARO design and operation was based on. The design requirements for the power distribution, standby power supply, and raceway system will be used for the conceptual design of electrical system.

  12. Advanced Research Workshop on Preparedness for Nuclear and Radiological Threats

    CERN Document Server

    Diamond, David; Nuclear Threats and Security Challenges

    2015-01-01

    With the dissolution of the Soviet Union the nuclear threats facing the world are constantly evolving and have grown more complex since the end of the Cold War. The diversion of complete weapon systems or nuclear material to rogue nations and terrorist organizations has increased. The events of the past years have proved the necessity to reevaluate these threats on a level never before considered.  In recognition that no single country possesses all of the answers to the critical scientific, institutional and legal questions associated with combating nuclear and radiological terrorism, the NATO Advanced Research Workshop on “Preparedness for Nuclear and Radiological Threats” and this proceeding was structured to promote wide-ranging, multi-national exploration of critical technology needs and underlying scientific challenges to reducing the threat of nuclear/radiological terrorism; to illustrate through country-specific presentations how resulting technologies were used in national programs; and to outli...

  13. Astonishing advances in mouse genetic tools for biomedical research.

    Science.gov (United States)

    Kaczmarczyk, Lech; Jackson, Walker S

    2015-01-01

    The humble house mouse has long been a workhorse model system in biomedical research. The technology for introducing site-specific genome modifications led to Nobel Prizes for its pioneers and opened a new era of mouse genetics. However, this technology was very time-consuming and technically demanding. As a result, many investigators continued to employ easier genome manipulation methods, though resulting models can suffer from overlooked or underestimated consequences. Another breakthrough, invaluable for the molecular dissection of disease mechanisms, was the invention of high-throughput methods to measure the expression of a plethora of genes in parallel. However, the use of samples containing material from multiple cell types could obfuscate data, and thus interpretations. In this review we highlight some important issues in experimental approaches using mouse models for biomedical research. We then discuss recent technological advances in mouse genetics that are revolutionising human disease research. Mouse genomes are now easily manipulated at precise locations thanks to guided endonucleases, such as transcription activator-like effector nucleases (TALENs) or the CRISPR/Cas9 system, both also having the potential to turn the dream of human gene therapy into reality. Newly developed methods of cell type-specific isolation of transcriptomes from crude tissue homogenates, followed by detection with next generation sequencing (NGS), are vastly improving gene regulation studies. Taken together, these amazing tools simplify the creation of much more accurate mouse models of human disease, and enable the extraction of hitherto unobtainable data.

  14. Method of advancing research and development of fast breeder reactors

    International Nuclear Information System (INIS)

    1988-01-01

    In the long term plan of atomic energy development and utilization, fast breeder reactors are to be developed as the main of the future nuclear power generation in Japan, and when their development is advanced, it has been decided to positively aim at building up the plutonium utilization system using FBRs superior to the uranium utilization system using LWRs. Also it has been decided that the development of FBRs requires to exert incessant efforts for a considerable long period under the proper cooperation system of government and people, and as for its concrete development, hereafter the deliberation is to be carried out in succession by the expert subcommittee on FBR development projects of the Atomic Energy Commission. The subcommittee was founded in May, 1986, to deliberate on the long term promotion measures for FBR development, the measures for promoting the research and development, the examination of the basic specification of a demonstration FBR, the measures for promoting international cooperation, and other important matters. As the results of investigation, the situation around the development of FBRs, the fundamentals at the time of promoting the research and development, the subjects of the research and development and so on are reported. (Kako, I.)

  15. 77 FR 16840 - Partnerships to Advance the National Occupational Research Agenda (NORA)

    Science.gov (United States)

    2012-03-22

    ... Advance the National Occupational Research Agenda (NORA) AGENCY: The National Institute for Occupational... following public meeting: ``Partnerships to Advance the National Occupational Research Agenda (NORA... Research Agenda (NORA) has been structured to engage partners with each other and/or with NIOSH to advance...

  16. 76 FR 25694 - Partnerships To Advance the National Occupational Research Agenda (NORA)

    Science.gov (United States)

    2011-05-05

    ... Advance the National Occupational Research Agenda (NORA) AGENCY: The National Institute for Occupational... following public meeting: ``Partnerships to Advance the National Occupational Research Agenda (NORA... Research Agenda (NORA) has been structured to engage partners with each other and/or with NIOSH to advance...

  17. 77 FR 66619 - Partnerships To Advance the National Occupational Research Agenda (NORA)

    Science.gov (United States)

    2012-11-06

    ... Advance the National Occupational Research Agenda (NORA) AGENCY: The National Institute for Occupational... following public meeting: ``Partnerships to Advance the National Occupational Research Agenda (NORA... Research Agenda (NORA) has been structured to engage partners with each other and/or with NIOSH to advance...

  18. Invited Review Article: Advanced light microscopy for biological space research

    Science.gov (United States)

    De Vos, Winnok H.; Beghuin, Didier; Schwarz, Christian J.; Jones, David B.; van Loon, Jack J. W. A.; Bereiter-Hahn, Juergen; Stelzer, Ernst H. K.

    2014-10-01

    As commercial space flights have become feasible and long-term extraterrestrial missions are planned, it is imperative that the impact of space travel and the space environment on human physiology be thoroughly characterized. Scrutinizing the effects of potentially detrimental factors such as ionizing radiation and microgravity at the cellular and tissue level demands adequate visualization technology. Advanced light microscopy (ALM) is the leading tool for non-destructive structural and functional investigation of static as well as dynamic biological systems. In recent years, technological developments and advances in photochemistry and genetic engineering have boosted all aspects of resolution, readout and throughput, rendering ALM ideally suited for biological space research. While various microscopy-based studies have addressed cellular response to space-related environmental stressors, biological endpoints have typically been determined only after the mission, leaving an experimental gap that is prone to bias results. An on-board, real-time microscopical monitoring device can bridge this gap. Breadboards and even fully operational microscope setups have been conceived, but they need to be rendered more compact and versatile. Most importantly, they must allow addressing the impact of gravity, or the lack thereof, on physiologically relevant biological systems in space and in ground-based simulations. In order to delineate the essential functionalities for such a system, we have reviewed the pending questions in space science, the relevant biological model systems, and the state-of-the art in ALM. Based on a rigorous trade-off, in which we recognize the relevance of multi-cellular systems and the cellular microenvironment, we propose a compact, but flexible concept for space-related cell biological research that is based on light sheet microscopy.

  19. Invited Review Article: Advanced light microscopy for biological space research

    International Nuclear Information System (INIS)

    De Vos, Winnok H.; Beghuin, Didier; Schwarz, Christian J.; Jones, David B.; Loon, Jack J. W. A. van; Bereiter-Hahn, Juergen; Stelzer, Ernst H. K.

    2014-01-01

    As commercial space flights have become feasible and long-term extraterrestrial missions are planned, it is imperative that the impact of space travel and the space environment on human physiology be thoroughly characterized. Scrutinizing the effects of potentially detrimental factors such as ionizing radiation and microgravity at the cellular and tissue level demands adequate visualization technology. Advanced light microscopy (ALM) is the leading tool for non-destructive structural and functional investigation of static as well as dynamic biological systems. In recent years, technological developments and advances in photochemistry and genetic engineering have boosted all aspects of resolution, readout and throughput, rendering ALM ideally suited for biological space research. While various microscopy-based studies have addressed cellular response to space-related environmental stressors, biological endpoints have typically been determined only after the mission, leaving an experimental gap that is prone to bias results. An on-board, real-time microscopical monitoring device can bridge this gap. Breadboards and even fully operational microscope setups have been conceived, but they need to be rendered more compact and versatile. Most importantly, they must allow addressing the impact of gravity, or the lack thereof, on physiologically relevant biological systems in space and in ground-based simulations. In order to delineate the essential functionalities for such a system, we have reviewed the pending questions in space science, the relevant biological model systems, and the state-of-the art in ALM. Based on a rigorous trade-off, in which we recognize the relevance of multi-cellular systems and the cellular microenvironment, we propose a compact, but flexible concept for space-related cell biological research that is based on light sheet microscopy

  20. Invited Review Article: Advanced light microscopy for biological space research

    Energy Technology Data Exchange (ETDEWEB)

    De Vos, Winnok H., E-mail: winnok.devos@uantwerpen.be [Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Antwerp (Belgium); Cell Systems and Imaging Research Group, Department of Molecular Biotechnology, Ghent University, Ghent (Belgium); Beghuin, Didier [Lambda-X, Nivelles (Belgium); Schwarz, Christian J. [European Space Agency (ESA), ESTEC, TEC-MMG, Noordwijk (Netherlands); Jones, David B. [Institute for Experimental Orthopaedics and Biomechanics, Philipps University, Marburg (Germany); Loon, Jack J. W. A. van [Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University Medical Center and Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam, Amsterdam (Netherlands); Bereiter-Hahn, Juergen; Stelzer, Ernst H. K. [Physical Biology, BMLS (FB15, IZN), Goethe University, Frankfurt am Main (Germany)

    2014-10-15

    As commercial space flights have become feasible and long-term extraterrestrial missions are planned, it is imperative that the impact of space travel and the space environment on human physiology be thoroughly characterized. Scrutinizing the effects of potentially detrimental factors such as ionizing radiation and microgravity at the cellular and tissue level demands adequate visualization technology. Advanced light microscopy (ALM) is the leading tool for non-destructive structural and functional investigation of static as well as dynamic biological systems. In recent years, technological developments and advances in photochemistry and genetic engineering have boosted all aspects of resolution, readout and throughput, rendering ALM ideally suited for biological space research. While various microscopy-based studies have addressed cellular response to space-related environmental stressors, biological endpoints have typically been determined only after the mission, leaving an experimental gap that is prone to bias results. An on-board, real-time microscopical monitoring device can bridge this gap. Breadboards and even fully operational microscope setups have been conceived, but they need to be rendered more compact and versatile. Most importantly, they must allow addressing the impact of gravity, or the lack thereof, on physiologically relevant biological systems in space and in ground-based simulations. In order to delineate the essential functionalities for such a system, we have reviewed the pending questions in space science, the relevant biological model systems, and the state-of-the art in ALM. Based on a rigorous trade-off, in which we recognize the relevance of multi-cellular systems and the cellular microenvironment, we propose a compact, but flexible concept for space-related cell biological research that is based on light sheet microscopy.

  1. Human Research Program Advanced Exercise Concepts (AEC) Overview

    Science.gov (United States)

    Perusek, Gail; Lewandowski, Beth; Nall, Marsha; Norsk, Peter; Linnehan, Rick; Baumann, David

    2015-01-01

    Exercise countermeasures provide benefits that are crucial for successful human spaceflight, to mitigate the spaceflight physiological deconditioning which occurs during exposure to microgravity. The NASA Human Research Program (HRP) within the Human Exploration and Operations Mission Directorate (HEOMD) is managing next generation Advanced Exercise Concepts (AEC) requirements development and candidate technology maturation to Technology Readiness Level (TRL) 7 (ground prototyping and flight demonstration) for all exploration mission profiles from Multi Purpose Crew Vehicle (MPCV) Exploration Missions (up to 21 day duration) to Mars Transit (up to 1000 day duration) missions. These validated and optimized exercise countermeasures systems will be provided to the ISS Program and MPCV Program for subsequent flight development and operations. The International Space Station (ISS) currently has three major pieces of operational exercise countermeasures hardware: the Advanced Resistive Exercise Device (ARED), the second-generation (T2) treadmill, and the cycle ergometer with vibration isolation system (CEVIS). This suite of exercise countermeasures hardware serves as a benchmark and is a vast improvement over previous generations of countermeasures hardware, providing both aerobic and resistive exercise for the crew. However, vehicle and resource constraints for future exploration missions beyond low Earth orbit will require that the exercise countermeasures hardware mass, volume, and power be minimized, while preserving the current ISS capabilities or even enhancing these exercise capabilities directed at mission specific physiological functional performance and medical standards requirements. Further, mission-specific considerations such as preservation of sensorimotor function, autonomous and adaptable operation, integration with medical data systems, rehabilitation, and in-flight monitoring and feedback are being developed for integration with the exercise

  2. Filling the gaps in SCWR materials research: advanced nuclear corrosion research facilities in Hamilton

    International Nuclear Information System (INIS)

    Krausher, J.L.; Zheng, W.; Li, J.; Guzonas, D.; Botton, G.

    2011-01-01

    Research efforts on materials selection and development in support of the design of supercritical water-cooled reactors (SCWRs) have produced a considerable amount of data on corrosion, creep and other related properties. Summaries of the data on corrosion [1] and stress corrosion cracking [2] have recently been produced. As research on the SCWR advances, gaps and limitations in the published data are being identified. In terms of corrosion properties, these gaps can be seen in several areas, including: 1) the test environment, 2) the physical and chemical severity of the tests conducted as compared with likely reactor service/operating conditions, and 3) the test methods used. While some of these gaps can be filled readily using existing facilities, others require the availability of advanced test facilities for specific tests and assessments. In this paper, highlights of the new materials research facilities jointly established in Hamilton by CANMET Materials Technology Laboratory and McMaster University are presented. (author)

  3. Research on Elemental Technology of Advanced Nuclear Fuel Performance Verification

    International Nuclear Information System (INIS)

    Kim, Yong Soo; Lee, Dong Uk; Jean, Sang Hwan; Koo, Min

    2003-04-01

    Most of current properties models and fuel performance models used in the performance evaluation codes are based on the in-pile data up to 33,000 MWd/MtU. Therefore, international experts are investigating the properties changes and developing advanced prediction models for high burn-up application. Current research is to develop high burn-up fission gas release model for the code and to support the code development activities by collecting data and models, reviewing/assessing the data and models together, and benchmarking the selected models against the appropriate in-pile data. For high burn-up applications, two stage two step fission gas release model is developed based on the real two diffusion process in the grain lattice and grain boundaries of the fission gases and the observation of accelerated release rate in the high burn-up. It is found that the prediction of this model is in excellent agreement with the in-pile measurement results, not only in the low burn-up but also in the high burn-up. This research is found that the importance of thermal conductivity of oxide fuel, especially in the high burn-up, is focused again. It is found that even the temperature dependent models differ from one to another and most of them overestimate the conductivity in the high burn-up. An in-pile data benchmarking of high LHGR fuel rod shows that the difference can reach 30%∼40%, which predicts 400 .deg. C lower than the real fuel centerline temperature. Recent models on the thermal expansion and heat capacity of oxide fuel are found to be well-defined. Irradiation swelling of the oxide fuel are now well-understood that in most cases in LWRs solid fission product swelling is dominant. Thus, the accumulation of in-pile data can enhance the accuracy of the model prediction, rather than theoretical modeling works. Thermo-physical properties of Zircaloy cladding are also well-defined and well-understood except the thermal expansion. However, it turns out that even the

  4. Advances in research methods for information systems research data mining, data envelopment analysis, value focused thinking

    CERN Document Server

    Osei-Bryson, Kweku-Muata

    2013-01-01

    Advances in social science research methodologies and data analytic methods are changing the way research in information systems is conducted. New developments in statistical software technologies for data mining (DM) such as regression splines or decision tree induction can be used to assist researchers in systematic post-positivist theory testing and development. Established management science techniques like data envelopment analysis (DEA), and value focused thinking (VFT) can be used in combination with traditional statistical analysis and data mining techniques to more effectively explore

  5. Research and applications of advanced fibers in China

    International Nuclear Information System (INIS)

    Xu Yunshu

    2007-01-01

    From simple matter to alloy, composite materials have been the frontier of contemporary material science. Its properties and application status designate the level of a country's material science. Polymer matrix, metal matrix and ceramics matrix advanced fibers reinforced composites are the important area of contemporary material science and the powerful supporting materials for the reformation of national defense industry and general industry. In the improvement and coordination of industrial production and the upgrade of human life's qualities, these materials are playing more and more important roles. There are great gaps between international level and China's level of both the research and development or the industrial status. The carbon fibers, which was started early in China, has not been put into large scale production yet. The properties of precursor fibers were the primary cause to prohibit the development of carbon fibers. About the SiC fibers, major progress was immerged in the CVI techniques to fabricate SiC f /SiC CMC; the current priority task is to research and develop high strength fibers with low oxygen content and excellent high temperature resistance. (authors)

  6. Astrid-2, an advanced microsatellite for auroral research

    Directory of Open Access Journals (Sweden)

    G. T. Marklund

    Full Text Available The successful launch of the Swedish microsatellite Astrid-2 in December 1998 began a new era of auroral research, with advanced microprobes of 30 kg or less used as research tools. Innovative technologies and low-mass solutions were used for the sensors and deployment systems to allow a fairly complete set of scientific instruments within the 10 kg allocated for the scientific payload. A newly developed wire boom deployment system proved to function excellently. During its seven month lifetime Astrid-2 collected more than 26 Gbytes of high-quality data of auroral electric and magnetic fields, and auroral particle and plasma characteristics from approximately 3000 orbits at an inclination of 83° and an altitude of about 1000 km. Scientific results cover a broad range of topics, from the physics of energization of auroral particles to how the magnetosphere responds to the energy input from the solar wind and global magnetic field modelling. The fulfilment of both the technological and the scientific mission objectives has opened entirely new possibilities to carry out low-budget multipoint measurements in near-Earth space.

    Key words. Ionosphere (auroral ionosphere; instruments and techniques – Magnetospheric physics (auroral phenomena

  7. Recent advances in Echinococcus genomics and stem cell research.

    Science.gov (United States)

    Koziol, U; Brehm, K

    2015-10-30

    Alveolar and cystic echinococcosis, caused by the metacestode larval stages of the tapeworms Echinococcus multilocularis and Echinococcus granulosus, respectively, are life-threatening diseases and very difficult to treat. The introduction of benzimidazole-based chemotherapy, which targets parasite β-tubulin, has significantly improved the life-span and prognosis of echinococcosis patients. However, benzimidazoles show only parasitostatic activity, are associated with serious adverse side effects and have to be administered for very long time periods, underlining the need for new drugs. Very recently, the nuclear genomes of E. multilocularis and E. granulosus have been characterised, revealing a plethora of data for gaining a deeper understanding of host-parasite interaction, parasite development and parasite evolution. Combined with extensive transcriptome analyses of Echinococcus life cycle stages these investigations also yielded novel clues for targeted drug design. Recent years also witnessed significant advancements in the molecular and cellular characterisation of the Echinococcus 'germinative cell' population, which forms a unique stem cell system that differs from stem cells of other organisms in the expression of several genes associated with the maintenance of pluripotency. As the only parasite cell type capable of undergoing mitosis, the germinative cells are central to all developmental transitions of Echinococcus within the host and to parasite expansion via asexual proliferation. In the present article, we will briefly introduce and discuss recent advances in Echinococcus genomics and stem cell research in the context of drug design and development. Interestingly, it turns out that benzimidazoles seem to have very limited effects on Echinococcus germinative cells, which could explain the high recurrence rates observed after chemotherapeutic treatment of echinococcosis patients. This clearly indicates that future efforts into the development of

  8. ARCHES: Advancing Research & Capacity in Hydrologic Education and Science

    Science.gov (United States)

    Milewski, A.; Fryar, A. E.; Durham, M. C.; Schroeder, P.; Agouridis, C.; Hanley, C.; Rotz, R. R.

    2013-12-01

    Educating young scientists and building capacity on a global scale is pivotal towards better understanding and managing our water resources. Based on this premise the ARCHES (Advancing Research & Capacity in Hydrologic Education and Science) program has been established. This abstract provides an overview of the program, links to access information, and describes the activities and outcomes of student participants from the Middle East and North Africa. The ARCHES program (http://arches.wrrs.uga.edu) is an integrated hydrologic education approach using online courses, field programs, and various hands-on workshops. The program aims to enable young scientists to effectively perform the high level research that will ultimately improve quality of life, enhance science-based decision making, and facilitate collaboration. Three broad, interlinked sets of activities are incorporated into the ARCHES program: (A1) the development of technical expertise, (A2) the development of professional contacts and skills, and (A3) outreach and long-term sustainability. The development of technical expertise (A1) is implemented through three progressive instructional sections. Section 1: Students were guided through a series of online lectures and exercises (Moodle: http://wrrs.uga.edu/moodle) covering three main topics (Remote Sensing, GIS, and Hydrologic Modeling). Section 2: Students participated in a hands-on workshop hosted at the University of Georgia's Water Resources and Remote Sensing Laboratory (WRRSL). Using ENVI, ArcGIS, and ArcSWAT, students completed a series of lectures and real-world applications (e.g., Development of Hydrologic Models). Section 3: Students participated in field studies (e.g., measurements of infiltration, recharge, streamflow, and water-quality parameters) conducted by U.S. partners and international collaborators in the participating countries. The development of professional contacts and skills (A2) was achieved through the promotion of networking

  9. Research investigations in oil shale, tar sand, coal research, advanced exploratory process technology, and advanced fuels research: Volume 1 -- Base program. Final report, October 1986--September 1993

    Energy Technology Data Exchange (ETDEWEB)

    Smith, V.E.

    1994-05-01

    Numerous studies have been conducted in five principal areas: oil shale, tar sand, underground coal gasification, advanced process technology, and advanced fuels research. In subsequent years, underground coal gasification was broadened to be coal research, under which several research activities were conducted that related to coal processing. The most significant change occurred in 1989 when the agreement was redefined as a Base Program and a Jointly Sponsored Research Program (JSRP). Investigations were conducted under the Base Program to determine the physical and chemical properties of materials suitable for conversion to liquid and gaseous fuels, to test and evaluate processes and innovative concepts for such conversions, to monitor and determine environmental impacts related to development of commercial-sized operations, and to evaluate methods for mitigation of potential environmental impacts. This report is divided into two volumes: Volume 1 consists of 28 summaries that describe the principal research efforts conducted under the Base Program in five topic areas. Volume 2 describes tasks performed within the JSRP. Research conducted under this agreement has resulted in technology transfer of a variety of energy-related research information. A listing of related publications and presentations is given at the end of each research topic summary. More specific and detailed information is provided in the topical reports referenced in the related publications listings.

  10. Advanced Accelerator Development Strategy Report: DOE Advanced Accelerator Concepts Research Roadmap Workshop

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2016-02-03

    Over a full two day period, February 2–3, 2016, the Office of High Energy Physics convened a workshop in Gaithersburg, MD to seek community input on development of an Advanced Accelerator Concepts (AAC) research roadmap. The workshop was in response to a recommendation by the HEPAP Accelerator R&D Subpanel [1] [2] to “convene the university and laboratory proponents of advanced acceleration concepts to develop R&D roadmaps with a series of milestones and common down selection criteria towards the goal for constructing a multi-TeV e+e– collider” (the charge to the workshop can be found in Appendix A). During the workshop, proponents of laser-driven plasma wakefield acceleration (LWFA), particle-beam-driven plasma wakefield acceleration (PWFA), and dielectric wakefield acceleration (DWFA), along with a limited number of invited university and laboratory experts, presented and critically discussed individual concept roadmaps. The roadmap workshop was preceded by several preparatory workshops. The first day of the workshop featured presentation of three initial individual roadmaps with ample time for discussion. The individual roadmaps covered a time period extending until roughly 2040, with the end date assumed to be roughly appropriate for initial operation of a multi-TeV e+e– collider. The second day of the workshop comprised talks on synergies between the roadmaps and with global efforts, potential early applications, diagnostics needs, simulation needs, and beam issues and challenges related to a collider. During the last half of the day the roadmaps were revisited but with emphasis on the next five to ten years (as specifically requested in the charge) and on common challenges. The workshop concluded with critical and unanimous endorsement of the individual roadmaps and an extended discussion on the characteristics of the common challenges. (For the agenda and list of participants see Appendix B.)

  11. 75 FR 30044 - Partnerships To Advance the National Occupational Research Agenda (NORA)

    Science.gov (United States)

    2010-05-28

    ... Advance the National Occupational Research Agenda (NORA) AGENCY: The National Institute for Occupational... following public meeting: ``Partnerships to Advance the National Occupational Research Agenda (NORA... (NORA) has been structured to engage partners with each other and/or with NIOSH to advance NORA...

  12. Advanced quantitative measurement methodology in physics education research

    Science.gov (United States)

    Wang, Jing

    The ultimate goal of physics education research (PER) is to develop a theoretical framework to understand and improve the learning process. In this journey of discovery, assessment serves as our headlamp and alpenstock. It sometimes detects signals in student mental structures, and sometimes presents the difference between expert understanding and novice understanding. Quantitative assessment is an important area in PER. Developing research-based effective assessment instruments and making meaningful inferences based on these instruments have always been important goals of the PER community. Quantitative studies are often conducted to provide bases for test development and result interpretation. Statistics are frequently used in quantitative studies. The selection of statistical methods and interpretation of the results obtained by these methods shall be connected to the education background. In this connecting process, the issues of educational models are often raised. Many widely used statistical methods do not make assumptions on the mental structure of subjects, nor do they provide explanations tailored to the educational audience. There are also other methods that consider the mental structure and are tailored to provide strong connections between statistics and education. These methods often involve model assumption and parameter estimation, and are complicated mathematically. The dissertation provides a practical view of some advanced quantitative assessment methods. The common feature of these methods is that they all make educational/psychological model assumptions beyond the minimum mathematical model. The purpose of the study is to provide a comparison between these advanced methods and the pure mathematical methods. The comparison is based on the performance of the two types of methods under physics education settings. In particular, the comparison uses both physics content assessments and scientific ability assessments. The dissertation includes three

  13. Advanced Photon Source research: Volume 1, Number 1, April 1998

    International Nuclear Information System (INIS)

    1998-04-01

    The following articles are included in this publication: (1) The Advanced Photon Source: A Brief Overview; (2) MAD Analysis of FHIT at the Structural Biology Center; (3) Advances in High-Energy-Resolution X-ray Scattering at Beamline 3-ID; (4) X-ray Imaging and Microspectroscopy of the Mycorrhyizal Fungus-Plant Symbiosis; (5) Measurement and Control of Particle-beam Trajectories in the Advanced Photon Storage Ring; (6) Beam Acceleration and Storage at the Advanced Photon Source; and (7) Experimental Facilities Operations and Current Status

  14. Recent theoretical, neural, and clinical advances in sustained attention research.

    Science.gov (United States)

    Fortenbaugh, Francesca C; DeGutis, Joseph; Esterman, Michael

    2017-05-01

    Models of attention often distinguish among attention subtypes, with classic models separating orienting, switching, and sustaining functions. Compared with other forms of attention, the neurophysiological basis of sustaining attention has received far less notice, yet it is known that momentary failures of sustained attention can have far-ranging negative effects in healthy individuals, and lasting sustained attention deficits are pervasive in clinical populations. In recent years, however, there has been increased interest in characterizing moment-to-moment fluctuations in sustained attention, in addition to the overall vigilance decrement, and understanding how these neurocognitive systems change over the life span and across various clinical populations. The use of novel neuroimaging paradigms and statistical approaches has allowed for better characterization of the neural networks supporting sustained attention and has highlighted dynamic interactions within and across multiple distributed networks that predict behavioral performance. These advances have also provided potential biomarkers to identify individuals with sustained attention deficits. These findings have led to new theoretical models explaining why sustaining focused attention is a challenge for individuals and form the basis for the next generation of sustained attention research, which seeks to accurately diagnose and develop theoretically driven treatments for sustained attention deficits that affect a variety of clinical populations. © 2017 New York Academy of Sciences.

  15. Recent theoretical, neural, and clinical advances in sustained attention research

    Science.gov (United States)

    Fortenbaugh, Francesca C.; DeGutis, Joseph; Esterman, Michael

    2017-01-01

    Models of attention often distinguish between attention subtypes, with classic models separating orienting, switching, and sustaining functions. Compared to other forms of attention, the neurophysiological basis of sustaining attention has received far less attention yet it is known that momentary failures of sustained attention can have far ranging negative impacts in healthy individuals and lasting sustained attention deficits are pervasive in clinical populations. In recent years, however, there has been increased interest in characterizing moment-to-moment fluctuations in sustained attention in addition to the overall vigilance decrement and understanding how these neurocognitive systems change over the lifespan and across various clinical populations. The use of novel neuroimaging paradigms and statistical approaches has allowed for better characterization of the neural networks supporting sustained attention, and highlighted dynamic interactions within and across multiple distributed networks that predict behavioral performance. These advances have also provided potential biomarkers to identify individuals with sustained attention deficits. These findings have led to new theoretical models of why sustaining focused attention is a challenge for individuals and form the basis for the next generation of sustained attention research, which seeks to accurately diagnose and develop theoretically-driven treatments for sustained attention deficits that affect a variety of clinical populations. PMID:28260249

  16. [Research advances in heavy metals pollution ecology of diatom].

    Science.gov (United States)

    Ding, Teng-Da; Ni, Wan-Min; Zhang, Jian-Ying

    2012-03-01

    Diatom, due to its high sensitivity to environmental change, is one of the bio-indicators of aquatic ecosystem health, and some typical diatom species have been applied to indicate the heavy metals pollution of water body. With the focus on the surface water heavy metals pollution, this paper reviewed the research advances in the toxic effect of heavy metals pollution on diatom, biosorption and bioaccumulation of heavy metals by diatom, ecological adaptation mechanisms of diatom to heavy metals pollution, and roles of diatom as bio-indicator and in ecological restoration of heavy metals pollution. The growth tendency of diatom and the morphological change of frustule under heavy metals pollution as well as the differences in heavy metals biosorption and bioaccumulation by diatom, the ecological adaptation mechanisms of diatom on heavy metals surface complexation and ion exchange, and the roles of diatom as bio-indicator and in ecological restoration of heavy metals polluted water body were also discussed. This review could provide scientific evidences for the prevention of aquatic ecosystems heavy metals pollution and related early warning techniques.

  17. Safety features and research needs of westinghouse advanced reactors

    International Nuclear Information System (INIS)

    Carelli, M.D.; Winters, J.W.; Cummins, W.E.; Bruschi, H.J.

    2002-01-01

    The three Westinghouse advanced reactors - AP600, AP1000 and IRIS - are at different levels of readiness. AP600 has received a Design Certification, its larger size version AP1000 is currently in the design certification process and IRIS has just completed its conceptual design and will initiate soon a licensing pre-application. The safety features of the passive designs AP600/AP1000 are presented, followed by the features of the more revolutionary IRIS, a small size modular integral reactor. A discussion of the IRIS safety by design approach is given. The AP600/AP1000 design certification is backed by completed testing and development which is summarized, together with a research program currently in progress which will extend AP600 severe accident test data to AP1000 conditions. While IRIS will of course rely on applicable AP600/1000 data, a very extensive testing campaign is being planned to address all the unique aspects of its design. Finally, IRIS plans to use a risk-informed approach in its licensing process. (authors)

  18. Hydrogen production from water: Recent advances in photosynthesis research

    Energy Technology Data Exchange (ETDEWEB)

    Greenbaum, E.; Lee, J.W. [Oak Ridge National Lab., TN (United States). Chemical Technology Div.

    1997-12-31

    The great potential of hydrogen production by microalgal water splitting is predicated on quantitative measurement of the algae`s hydrogen-producing capability, which is based on the following: (1) the photosynthetic unit size of hydrogen production; (2) the turnover time of photosynthetic hydrogen production; (3) thermodynamic efficiencies of conversion of light energy into the Gibbs free energy of molecular hydrogen; (4) photosynthetic hydrogen production from sea water using marine algae; (5) the potential for research advances using modern methods of molecular biology and genetic engineering to maximize hydrogen production. ORNL has shown that sustained simultaneous photoevolution of molecular hydrogen and oxygen can be performed with mutants of the green alga Chlamydomonas reinhardtii that lack a detectable level of the Photosystem I light reaction. This result is surprising in view of the standard two-light reaction model of photosynthesis and has interesting scientific and technological implications. This ORNL discovery also has potentially important implications for maximum thermodynamic conversion efficiency of light energy into chemical energy by green plant photosynthesis. Hydrogen production performed by a single light reaction, as opposed to two, implies a doubling of the theoretically maximum thermodynamic conversion efficiency from {approx}10% to {approx}20%.

  19. Experimental research on safety assurance of advanced WWER fuel cycles

    International Nuclear Information System (INIS)

    Krainov, Ju.; Kukushkin, Ju.

    2002-01-01

    The paper presents the results of experimental investigations on substantiation of implementation of a modernized butt joint for the WWER-440 reactor, carried out in the critical test facility 'P' in the RRC 'Kurchatov Institute'. The comparison results of the calculation and experimental data obtained in the physical startup of Volgodonsk NPP-1 with the WWER-1000 are also given. In the implementation of four-year fuel cycle in the WWER-440 with the average enrichment of fuel makeup 3.82% it was solved to conduct experimental research of power distribution in the vicinity of control rod butt junction. Moreover, it was assumed that adequate actions should be applied to eliminate inadmissible power jumps, if necessary. It is not available to measure their values in NPP conditions. Therefore, the power distribution near the butt joint was studied in a 19-rod bank installed in the critical test facility 'P' first for the normal design of the joint when surrounding fuel assemblies enrichment goes up. Then a set of calculation and tests was fulfilled to optimize a butt junction design. On the base of this research the composition of a butt junction was advanced by placing Hf plates into the junction. The effectiveness of modernized butt joint design was experimentally confirmed. In Volgodonsk NPP-1 with WWER-1000 the four-year fuel cycle is being implemented. During the physical startup of the reactor the measurements of the reactivity effects and coefficients were measured at the minimum controlled flux level, and the parameters of a number of critical states were recorded. The data obtained were compared with the calculation. The validity of the certified code package for forecasting the neutronic characteristics of WWER-1000 cores in the implementation of a four year fuel cycle has been supported (Authors)

  20. Advances in Rodent Research Missions on the International Space Station

    Science.gov (United States)

    Choi, S. Y.; Ronca, A.; Leveson-Gower, D.; Gong, C.; Stube, K.; Pletcher, D.; Wigley, C.; Beegle, J.; Globus, R. K.

    2016-01-01

    A research platform for rodent experiment on the ISS is a valuable tool for advancing biomedical research in space. Capabilities offered by the Rodent Research project developed at NASA Ames Research Center can support experiments of much longer duration on the ISS than previous experiments performed on the Space Shuttle. NASAs Rodent Research (RR)-1 mission was completed successfully and achieved a number of objectives, including validation of flight hardware, on-orbit operations, and science capabilities as well as support of a CASIS-sponsored experiment (Novartis) on muscle atrophy. Twenty C57BL6J adult female mice were launched on the Space-X (SpX) 4 Dragon vehicle, and thrived for up to 37 days in microgravity. Daily health checks of the mice were performed during the mission via downlinked video; all flight animals were healthy and displayed normal behavior, and higher levels of physical activity compared to ground controls. Behavioral analysis demonstrated that Flight and Ground Control mice exhibited the same range of behaviors, including eating, drinking, exploratory behavior, self- and allo-grooming, and social interactions indicative of healthy animals. The animals were euthanized on-orbit and select tissues were collected from some of the mice on orbit to assess the long-term sample storage capabilities of the ISS. In general, the data obtained from the flight mice were comparable to those from the three groups of control mice (baseline, vivarium and ground controls, which were housed in flight hardware), showing that the ISS has adequate capability to support long-duration rodent experiments. The team recovered 35 tissues from 40 RR-1 frozen carcasses, yielding 3300 aliquots of tissues to distribute to the scientific community in the U.S., including NASAs GeneLab project and scientists via Space Biology's Biospecimen Sharing Program Ames Life Science Data Archive. Tissues also were distributed to Russian research colleagues at the Institute for

  1. Advanced Pediatric Brain Imaging Research and Training Program

    Science.gov (United States)

    2012-10-01

    contrast, diffusion-weighted techniques, and MR spectroscopy (single voxel, multivoxel, PEPSI ). Mechanisms of recovery include application of the...key methods to build academic portfolios, understand the APT process and market their academic advancement Faculty Development: 103...APT process and market their academic advancement Faculty Development: 104 Leadership Faculty Development: Enhancing Team Effectiveness

  2. Advanced Low-Noise Research Fan Stage Design

    Science.gov (United States)

    Neubert, Robert; Bock, Larry; Malmborg, Eric; Owen-Peer, William

    1997-01-01

    This report describes the design of the Advanced Low-Noise Research Fan stage. The fan is a variable pitch design, which is designed at the cruise pitch condition. Relative to the cruise setting, the blade is closed at takeoff and opened for reverse thrust operation. The fan stage is a split flow design with fan exit guide vanes (FEGVs) and core stators. The fan stage design is combined with a nacelle and engine core duct to form a powered fan/nacelle subscale model. This model is intended for use in combined aerodynamic, acoustic, and structural testing in a wind tunnel. The fan has an outer diameter of 22 in. and a hub-to-tip of 0.426 in., which allows the use of existing NASA fan and cowl force balance and rig drive systems. The design parameters were selected to permit valid acoustic and aerodynamic comparisons with the Pratt & Whitney (P&W) 17- and 22-in. rigs previously tested under NASA contract. The fan stage design is described in detail. The results of the design axisymmetric and Navier-Stokes aerodynamic analysis are presented at the critical design conditions. The structural analysis of the fan rotor and attachment is included. The blade and attachment are predicted to have adequate low-cycle fatigue life and an acceptable operating range without resonant stress or flutter. The stage was acoustically designed with airfoil counts in the FEGV and core stator to minimize noise. A fan/FEGV tone analysis developed separately under NASA contract was used to determine the optimum airfoil counts. The fan stage was matched to the existing nacelle, designed under the previous P&W low-noise contract, to form a fan/nacelle model for wind tunnel testing. It is an axisymmetric nacelle for convenience in testing and analysis. Previous testing confirmed that the nacelle performed as required at various aircraft operating conditions.

  3. Conjugate heat transfer simulations of advanced research reactor fuel

    Energy Technology Data Exchange (ETDEWEB)

    Piro, M.H.A., E-mail: pirom@aecl.ca; Leitch, B.W.

    2014-07-01

    Highlights: • Temperature predictions are enhanced by coupling heat transfer in solid and fluid zones. • Seven different cases are considered to observe trends in predicted temperature and pressure. • The seven cases consider high/medium/low power, flow, burnup, fuel material and geometry. • Simulations provide temperature predictions for performance/safety. Boiling is unlikely. • Simulations demonstrate that a candidate geometry can enhance performance/safety. - Abstract: The current work presents numerical simulations of coupled fluid flow and heat transfer of advanced U–Mo/Al and U–Mo/Mg research reactor fuels in support of performance and safety analyses. The objective of this study is to enhance predictions of the flow regime and fuel temperatures through high fidelity simulations that better capture various heat transfer pathways and with a more realistic geometric representation of the fuel assembly in comparison to previous efforts. Specifically, thermal conduction, convection and radiation mechanisms are conjugated between the solid and fluid regions. Also, a complete fuel element assembly is represented in three dimensional space, permitting fluid flow and heat transfer to be simulated across the entire domain. Seven case studies are examined that vary the coolant inlet conditions, specific power, and burnup to investigate the predicted changes in the pressure drop in the coolant and the fuel, clad and coolant temperatures. In addition, an alternate fuel geometry is considered with helical fins (replacing straight fins in the existing design) to investigate the relative changes in predicted fluid and solid temperatures. Numerical simulations predict that the clad temperature is sensitive to changes in the thermal boundary layer in the coolant, particularly in simultaneously developing flow regions, while the temperature in the fuel is anticipated to be unaffected. Finally, heat transfer between fluid and solid regions is enhanced with

  4. Advanced tokamak research with integrated modeling in JT-60 Upgrade

    International Nuclear Information System (INIS)

    Hayashi, N.

    2010-01-01

    Researches on advanced tokamak (AT) have progressed with integrated modeling in JT-60 Upgrade [N. Oyama et al., Nucl. Fusion 49, 104007 (2009)]. Based on JT-60U experimental analyses and first principle simulations, new models were developed and integrated into core, rotation, edge/pedestal, and scrape-off-layer (SOL)/divertor codes. The integrated models clarified complex and autonomous features in AT. An integrated core model was implemented to take account of an anomalous radial transport of alpha particles caused by Alfven eigenmodes. It showed the reduction in the fusion gain by the anomalous radial transport and further escape of alpha particles. Integrated rotation model showed mechanisms of rotation driven by the magnetic-field-ripple loss of fast ions and the charge separation due to fast-ion drift. An inward pinch model of high-Z impurity due to the atomic process was developed and indicated that the pinch velocity increases with the toroidal rotation. Integrated edge/pedestal model clarified causes of collisionality dependence of energy loss due to the edge localized mode and the enhancement of energy loss by steepening a core pressure gradient just inside the pedestal top. An ideal magnetohydrodynamics stability code was developed to take account of toroidal rotation and clarified a destabilizing effect of rotation on the pedestal. Integrated SOL/divertor model clarified a mechanism of X-point multifaceted asymmetric radiation from edge. A model of the SOL flow driven by core particle orbits which partially enter the SOL was developed by introducing the ion-orbit-induced flow to fluid equations.

  5. Research for Foreign Advanced Ports for Protection and Development Experience

    Science.gov (United States)

    Zhang, Lu; Tian, Mingjing; Zhao, Junjie; Shou, Youping; Wang, Ning; Qiao, Jianzhe; Li, Guanglou

    2018-04-01

    Into the twenty-first century, the process globalization of economic and trade is getting faster and faster, As of 2014, China's annual port trading amount topped the world, But in the port of environmental protection sustainable development approach with foreign advanced port environmental management concept has a big gap. Combined with the present situation of modern ports in China. Drawing lessons from foreign advanced environmental protection idea of port, in order to promote the protection of port environment in our country. The experience of protection and development of foreign advanced port environment will be discussed and discussed.

  6. 76 FR 66071 - Partnerships To Advance the National Occupational Research Agenda (NORA)

    Science.gov (United States)

    2011-10-25

    ... Advance the National Occupational Research Agenda (NORA) AGENCY: The National Institute for Occupational... following public meeting: ``Partnerships to Advance the National Occupational Research Agenda (NORA... Occupational Research Agenda (NORA) has been structured to engage partners with each other and/or with NIOSH to...

  7. 75 FR 63495 - Partnerships To Advance the National Occupational Research Agenda (NORA)

    Science.gov (United States)

    2010-10-15

    ... Advance the National Occupational Research Agenda (NORA) AGENCY: The National Institute for Occupational... following public meeting: ``Partnerships to Advance the National Occupational Research Agenda (NORA... Occupational Research Agenda (NORA) has been structured to engage partners with each other and/or with NIOSH to...

  8. 78 FR 30306 - Partnerships To Advance the National Occupational Research Agenda (NORA)

    Science.gov (United States)

    2013-05-22

    ... Advance the National Occupational Research Agenda (NORA) AGENCY: The National Institute for Occupational... following public meeting: ``Partnerships to Advance the National Occupational Research Agenda (NORA... Occupational Research Agenda (NORA) has been structured to engage partners with each other and/or with NIOSH to...

  9. Literary Discussions and Advanced Speaking Functions: Researching the (Dis)Connection

    Science.gov (United States)

    Donato, Richard; Brooks, Frank B.

    2004-01-01

    This study investigated the discourse of class discussion in the advanced undergraduate Spanish literature course. Motivating this study was the need for research to determine how discussion in advanced undergraduate literature courses provides discourse opportunities to students to develop advanced language functions, as defined in the ACTFL…

  10. NATO Advanced Research Workshop on Brilliant Light Facilities and Research in Life and Material Sciences

    CERN Document Server

    Tsakanov, Vasili; Brilliant Light in Life and Material Sciences

    2007-01-01

    The present book contains an excellent overview of the status and highlights of brilliant light facilities and their applications in biology, chemistry, medicine, materials and environmental sciences. Overview papers on diverse fields of research by leading experts are accompanied by the highlights in the near and long-term perspectives of brilliant X-Ray photon beam usage for fundamental and applied research. The book includes advanced topics in the fields of high brightness photon beams, instrumentation, the spectroscopy, microscopy, scattering and imaging experimental techniques and their applications. The book is strongly recommended for students, engineers and scientists in the field of accelerator physics, X-ray optics and instrumentation, life, materials and environmental sciences, bio and nanotechnology.

  11. Advancing the research agenda for diagnostic error reduction

    NARCIS (Netherlands)

    Zwaan, L.; Schiff, G.D.; Singh, H.

    2013-01-01

    Diagnostic errors remain an underemphasised and understudied area of patient safety research. We briefly summarise the methods that have been used to conduct research on epidemiology, contributing factors and interventions related to diagnostic error and outline directions for future research.

  12. Advances in Medicinal Plant Research | Hafez | African Journal of ...

    African Journals Online (AJOL)

    African Journal of Food, Agriculture, Nutrition and Development. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 11, No 6 (2011) >. Log in or Register to get access to full text downloads.

  13. 2013 Summary of Advances in Autism Spectrum Disorder Research

    Science.gov (United States)

    Interagency Autism Coordinating Committee, 2014

    2014-01-01

    Each year, the Interagency Autism Coordinating Committee (IACC) releases its annual list of scientific advances that represent significant progress in the field. The 20 studies selected have given new insight into the complex causes of autism and potential risk factors, studied clues that could lead to earlier diagnosis, and evaluated promising…

  14. Advanced Categorical Statistics: Issues and Applications in Communication Research.

    Science.gov (United States)

    Denham, Bryan E.

    2002-01-01

    Discusses not only the procedures, assumptions, and applications of advanced categorical statistics, but also covers some common misapplications, from which a great deal can be learned. Addresses the use and limitations of cross-tabulation and chi-square analysis, as well as issues such as observation independence and artificial inflation of a…

  15. School Integration Matters: Research-Based Strategies to Advance Equity

    Science.gov (United States)

    Frankenberg, Erica, Ed.; Garces, Liliana M., Ed.; Hopkins, Megan, Ed.

    2016-01-01

    More than 60 years after the "Brown v. Board of Education" decision declared segregated schooling inherently unequal, this timely book sheds light on how and why U.S. schools are experiencing increasing segregation along racial, socioeconomic, and linguistic lines. It offers policy and programmatic alternatives for advancing equity and…

  16. Research and development on the application of advanced control technologies to advanced nuclear reactor systems: A US national perspective

    International Nuclear Information System (INIS)

    White, J.D.; Monson, L.R.; Carrol, D.G.; Dayal, Y.

    1989-01-01

    Control system designs for nuclear power plants are becoming more advanced through the use of digital technology and automation. This evolution is taking place because of: (1) the limitations in analog based control system performance and maintenance and availability and (2) the promise of significant improvement in plant operation and availability due to advances in digital and other control technologies. Digital retrofits of control systems in US nuclear plants are occurring now. Designs of control and protection systems for advanced LWRs are based on digital technology. The use of small inexpensive, fast, large-capacity computers in these designs is the first step of an evolutionary process described in this paper. Under the sponsorship of the US Department of Energy (DOE), Oak Ridge National Laboratory, Argonne National Laboratory, GE Nuclear Energy and several universities are performing research and development in the application of advances in control theory, software engineering, advanced computer architectures, artificial intelligence, and man-machine interface analysis to control system design. The target plant concept for the work described in this paper is the Power Reactor Inherently Safe Module reactor (PRISM), an advanced modular liquid metal reactor concept. This and other reactor designs which provide strong passive responses to operational upsets or accidents afford good opportunities to apply these advances in control technology. 18 refs., 5 figs

  17. Mentoring advanced practice nurses in research: recommendations from a pilot program.

    Science.gov (United States)

    Leung, Doris; Widger, Kimberley; Howell, Doris; Nelson, Sioban; Molassiotis, Alex

    2012-01-01

    Advanced Practice Nurses (APNs) need research skills to develop and advance their practice and, yet, many have limited access to research training and support following completion of their advanced degree. In this paper we report on the development, delivery, and evaluation of an innovative pilot program that combined research training and one-to-one mentorship for nine APNs in conducting research relevant to their practice. The program was organized within an academic institution and its affiliated hospitals in Toronto, Canada. Our experience with this program may assist those in other organizations to plan and deliver a similar program for APN research mentorship.

  18. Using research to transform care for women veterans: advancing the research agenda and enhancing research-clinical partnerships.

    Science.gov (United States)

    Yano, Elizabeth M; Bastian, Lori A; Bean-Mayberry, Bevanne; Eisen, Seth; Frayne, Susan; Hayes, Patricia; Klap, Ruth; Lipson, Linda; Mattocks, Kristin; McGlynn, Geraldine; Sadler, Anne; Schnurr, Paula; Washington, Donna L

    2011-01-01

    The purpose of this paper is to report on the outcomes of the 2010 VA Women's Health Services Research Conference, which brought together investigators interested in pursuing research on women veterans and women in the military with leaders in women's health care delivery and policy within and outside the VA, to significantly advance the state and future direction of VA women's health research and its potential impacts on practice and policy. Building on priorities assembled in the previous VA research agenda (2004) and the research conducted in the intervening six years, we used an array of approaches to foster research-clinical partnerships that integrated the state-of-the-science with the informational and strategic needs of senior policy and practice leaders. With demonstrated leadership commitment and support, broad field-based participation, strong interagency collaboration and a push to accelerate the move from observational to interventional and implementation research, the Conference provided a vital venue for establishing the foundation for a new research agenda. In this paper, we provide the historical evolution of the emergence of women veterans' health services research and an overview of the research in the intervening years since the first VA women's health research agenda. We then present the resulting VA Women's Health Research Agenda priorities and supporting activities designed to transform care for women veterans in six broad areas of study, including access to care and rural health; primary care and prevention; mental health; post deployment health; complex chronic conditions, aging and long-term care; and reproductive health. Published by Elsevier Inc.

  19. Experimental Advanced Airborne Research Lidar (EAARL) Data Processing Manual

    Science.gov (United States)

    Bonisteel, Jamie M.; Nayegandhi, Amar; Wright, C. Wayne; Brock, John C.; Nagle, David

    2009-01-01

    The Experimental Advanced Airborne Research Lidar (EAARL) is an example of a Light Detection and Ranging (Lidar) system that utilizes a blue-green wavelength (532 nanometers) to determine the distance to an object. The distance is determined by recording the travel time of a transmitted pulse at the speed of light (fig. 1). This system uses raster laser scanning with full-waveform (multi-peak) resolving capabilities to measure submerged topography and adjacent coastal land elevations simultaneously (Nayegandhi and others, 2009). This document reviews procedures for the post-processing of EAARL data using the custom-built Airborne Lidar Processing System (ALPS). ALPS software was developed in an open-source programming environment operated on a Linux platform. It has the ability to combine the laser return backscatter digitized at 1-nanosecond intervals with aircraft positioning information. This solution enables the exploration and processing of the EAARL data in an interactive or batch mode. ALPS also includes modules for the creation of bare earth, canopy-top, and submerged topography Digital Elevation Models (DEMs). The EAARL system uses an Earth-centered coordinate and reference system that removes the necessity to reference submerged topography data relative to water level or tide gages (Nayegandhi and others, 2006). The EAARL system can be mounted in an array of small twin-engine aircraft that operate at 300 meters above ground level (AGL) at a speed of 60 meters per second (117 knots). While other systems strive to maximize operational depth limits, EAARL has a narrow transmit beam and receiver field of view (1.5 to 2 milliradians), which improves the depth-measurement accuracy in shallow, clear water but limits the maximum depth to about 1.5 Secchi disk depth (~20 meters) in clear water. The laser transmitter [Continuum EPO-5000 yttrium aluminum garnet (YAG)] produces up to 5,000 short-duration (1.2 nanosecond), low-power (70 microjoules) pulses each second

  20. Proceedings of 1995 the first Taedok international fusion symposium on advanced tokamak researches

    Energy Technology Data Exchange (ETDEWEB)

    Kim, S K; Lee, K W; Hwang, C K; Hong, B G; Hong, G W [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1995-05-01

    This proceeding is from the First Taeduk International Fusion Symposium on advanced tokamak research, which was held at Korea Atomic Energy Research Institute, Taeduk Science Town, Korea on March 28-29, 1995. (Author) .new.

  1. Proceedings of 1995 the first Taedok international fusion symposium on advanced tokamak researches

    International Nuclear Information System (INIS)

    Kim, S. K.; Lee, K. W.; Hwang, C. K.; Hong, B. G.; Hong, G. W.

    1995-05-01

    This proceeding is from the First Taeduk International Fusion Symposium on advanced tokamak research, which was held at Korea Atomic Energy Research Institute, Taeduk Science Town, Korea on March 28-29, 1995. (Author) .new

  2. Status and future directions for advanced accelerator research - conventional and non-conventional collider concepts

    International Nuclear Information System (INIS)

    Siemann, R.H.

    1997-01-01

    The relationship between advanced accelerator research and future directions for particle physics is discussed. Comments are made about accelerator research trends in hadron colliders, muon colliders, and e + 3 - linear colliders

  3. Advances in business ICT new ideas from ongoing research

    CERN Document Server

    Mach-Król, Maria; Olszak, Celina

    2017-01-01

    This book discusses the effective use of modern ICT solutions for business needs, including the efficient use of IT resources, decision support systems, business intelligence, data mining and advanced data processing algorithms, as well as the processing of large datasets (inter alia social networking such as Twitter and Facebook, etc.). The ability to generate, record and process qualitative and quantitative data, including in the area of big data, the Internet of Things (IoT) and cloud computing offers a real prospect of significant improvements for business, as well as the operation of a company within Industry 4.0. The book presents new ideas, approaches, solutions and algorithms in the area of knowledge representation, management and processing, quantitative and qualitative data processing (including sentiment analysis), problems of simulation performance, and the use of advanced signal processing to increase the speed of computation. The solutions presented are also aimed at the effective use of busines...

  4. Advanced spallation neutron sources for condensed matter research

    International Nuclear Information System (INIS)

    Lovesey, S.W.; Stirling, G.C.

    1984-03-01

    Advanced spallation neutron sources afford significant advantages over existing high flux reactors. The effective flux is much greater than that currently available with reactor sources. A ten-fold increase in neutron flux will be a major benefit to a wide range of condensed matter studies, and it will realise important experiments that are marginal at reactor sources. Moreover, the high intensity of epithermal neutrons open new vistas in studies of electronic states and molecular vibrations. (author)

  5. Advanced Pediatric Brain Imaging Research and Training Program

    Science.gov (United States)

    2015-10-01

    iii) the necessary skills to apply advanced MRI techniques to study brain injury, and to facilitate the diagnosis , management, and ultimately...1) in facilitating diagnosis , management and rehabilitation as well as plasticity following brain injury. Our progress in transitioning these...seek organizational buy- in and implement the training portal as follows. In order to familiarize the target audiences at the military bases with the

  6. Federal Plan for Advanced Networking Research and Development

    Data.gov (United States)

    Networking and Information Technology Research and Development, Executive Office of the President — In the four decades since Federal research first enabled computers to send and receive data over networks, U.S. government research and development R and D in...

  7. Big data in psychology: A framework for research advancement.

    Science.gov (United States)

    Adjerid, Idris; Kelley, Ken

    2018-02-22

    The potential for big data to provide value for psychology is significant. However, the pursuit of big data remains an uncertain and risky undertaking for the average psychological researcher. In this article, we address some of this uncertainty by discussing the potential impact of big data on the type of data available for psychological research, addressing the benefits and most significant challenges that emerge from these data, and organizing a variety of research opportunities for psychology. Our article yields two central insights. First, we highlight that big data research efforts are more readily accessible than many researchers realize, particularly with the emergence of open-source research tools, digital platforms, and instrumentation. Second, we argue that opportunities for big data research are diverse and differ both in their fit for varying research goals, as well as in the challenges they bring about. Ultimately, our outlook for researchers in psychology using and benefiting from big data is cautiously optimistic. Although not all big data efforts are suited for all researchers or all areas within psychology, big data research prospects are diverse, expanding, and promising for psychology and related disciplines. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  8. Economics of coal conversion processing. Advances in coal gasification: support research. Advances in coal gasification: process development and analysis

    Energy Technology Data Exchange (ETDEWEB)

    1978-01-01

    The fall meeting of the American Chemical Society, Division of Fuel Chemistry, was held at Miami Beach, Florida, September 10-15, 1978. Papers involved the economics of coal conversion processing and advances in coal gasification, especially support research and process development and analysis. Fourteen papers have been entered individually into EDB and ERA; three papers had been entered previously from other sources. (LTN)

  9. A CTSA Agenda to Advance Methods for Comparative Effectiveness Research

    Science.gov (United States)

    Helfand, Mark; Tunis, Sean; Whitlock, Evelyn P.; Pauker, Stephen G.; Basu, Anirban; Chilingerian, Jon; Harrell Jr., Frank E.; Meltzer, David O.; Montori, Victor M.; Shepard, Donald S.; Kent, David M.

    2011-01-01

    Abstract Clinical research needs to be more useful to patients, clinicians, and other decision makers. To meet this need, more research should focus on patient‐centered outcomes, compare viable alternatives, and be responsive to individual patients’ preferences, needs, pathobiology, settings, and values. These features, which make comparative effectiveness research (CER) fundamentally patient‐centered, challenge researchers to adopt or develop methods that improve the timeliness, relevance, and practical application of clinical studies. In this paper, we describe 10 priority areas that address 3 critical needs for research on patient‐centered outcomes (PCOR): (1) developing and testing trustworthy methods to identify and prioritize important questions for research; (2) improving the design, conduct, and analysis of clinical research studies; and (3) linking the process and outcomes of actual practice to priorities for research on patient‐centered outcomes. We argue that the National Institutes of Health, through its clinical and translational research program, should accelerate the development and refinement of methods for CER by linking a program of methods research to the broader portfolio of large, prospective clinical and health system studies it supports. Insights generated by this work should be of enormous value to PCORI and to the broad range of organizations that will be funding and implementing CER. Clin Trans Sci 2011; Volume 4: 188–198 PMID:21707950

  10. NATO Advanced Research Workshop on Vectorization of Advanced Methods for Molecular Electronic Structure

    CERN Document Server

    1984-01-01

    That there have been remarkable advances in the field of molecular electronic structure during the last decade is clear not only to those working in the field but also to anyone else who has used quantum chemical results to guide their own investiga­ tions. The progress in calculating the electronic structures of molecules has occurred through the truly ingenious theoretical and methodological developments that have made computationally tractable the underlying physics of electron distributions around a collection of nuclei. At the same time there has been consider­ able benefit from the great advances in computer technology. The growing sophistication, declining costs and increasing accessibi­ lity of computers have let theorists apply their methods to prob­ lems in virtually all areas of molecular science. Consequently, each year witnesses calculations on larger molecules than in the year before and calculations with greater accuracy and more com­ plete information on molecular properties. We can surel...

  11. Retrospect and prospect: advances and future strategies in climate research

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    A brief review of the progress in climate research and a prospect on its further development in the 21st century is presented. Some key findings including the concept of climate system, the discovery of climatic multi-equilibrium and abrupt climate changes, and the recognition of human activities as an important force of climate change made breakthroughs in climatology possible during last few decades. The adaptation to climatic and global change emerged as a new aspect of climatic research during the 1990s. Climate research will break through in the observation of the global system, in the analysis of mass data, in the deepening of research on the mechanism of climatic change, and in the improvement of models. In the applied fields of climate research, there will be substantial progress in the research on adaptation to global change and sustainable development, on orderly human activities, and climate modification.

  12. Combinatorial methods for advanced materials research and development

    Energy Technology Data Exchange (ETDEWEB)

    Cremer, R.; Dondorf, S.; Hauck, M.; Horbach, D.; Kaiser, M.; Krysta, S.; Kyrylov, O.; Muenstermann, E.; Philipps, M.; Reichert, K.; Strauch, G. [Rheinisch-Westfaelische Technische Hochschule Aachen (Germany). Lehrstuhl fuer Theoretische Huettenkunde

    2001-10-01

    The applicability of combinatorial methods in developing advanced materials is illustrated presenting four examples for the deposition and characterization of one- and two-dimensionally laterally graded coatings, which were deposited by means of (reactive) magnetron sputtering and plasma-enhanced chemical vapor deposition. To emphasize the advantages of combinatorial approaches, metastable hard coatings like (Ti,Al)N and (Ti,Al,Hf)N respectively, as well as Ge-Sb-Te based films for rewritable optical data storage were investigated with respect to the relations between structure, composition, and the desired materials properties. (orig.)

  13. Research advancements and applications of carboranes in nuclear medicinal chemistry

    International Nuclear Information System (INIS)

    Chen Wen; Wei Hongyuan; Luo Shunzhong

    2011-01-01

    Because of their uniquely high thermal and chemical stabilities, carboranes have become a subject of study with high interest in the chemistry of supra molecules, catalysts and radiopharmaceuticals. In recent years, the role of carboranes in nuclear medicinal chemistry has been diversified, from the traditional use in boron neutron capture therapy (BNCT), to the clinical applications in molecular radio imaging and therapy. This paper provides an overview of the synthesis and characterization of carboranes and their applications in nuclear medicinal chemistry, with highlights of recent key advancements in the re- search areas of BNCT and radio imaging. (authors)

  14. Advancing prion science: guidance for the National Prion Research Program

    National Research Council Canada - National Science Library

    Erdtmann, Rick; Sivitz, Laura

    2004-01-01

    ...€™s National Prion Research Program (NPRP). Transmissible spongiform encephalopathies (TSEs), also called prion diseases, are invariably fatal neurodegenerative infectious diseases that include bovine spongiform encephalopathy...

  15. EUFAR training opportunities to advance European airborne research

    Science.gov (United States)

    Reusen, I.; Brenguier, J.-L.; Brown, P.; Wendish, M.

    2009-04-01

    EUFAR, EUropean Facilities for Airborne Research, is an FP7 project (http://www.eufar.net) funded by the European Commission with 33 partners that aims at providing and improving the access to European airborne facilities (i.e. aircraft, airborne instruments, data processing centres) for researchers in environmental and geo-sciences through Networking Activities, Transnational Access and Joint Research Activities. This paper reports on the training opportunities within EUFAR for European researchers. In EUFAR three types of training opportunities are offered: 1) Participate in training courses (ET-TC) 2) Join an existing field campaign (ET-EC) 3) Participate in the design of a new field campaign (ET-TA), in the frame of EUFAR Transnational Access and tutored by more experienced researchers. During the 4-year EUFAR project (2008-2012), 4 training courses covering the complete chain from acquisition to interpretation of airborne data and images will be organised during spring/summer for early-stage researchers as well as university lecturers (new in FP7 EUFAR) in airborne research. The training courses will have an equal focus on theory and practical training/demonstration and each training course will be accompanied by a "student" airborne field campaign. Participants will be trained by top-class scientists, aircraft and/or instrument operators and each participant will get the opportunity to design his/her own experiment and to participate to that flight experiment. Furthermore, researchers have the opportunity to join an existing field campaign and work with more experienced researchers, aircraft and/or instrument operators. The list of airborne field campaigns open to join and the eligibility criteria, can be consulted at the EUFAR website. Finally, researchers have the opportunity to participate in the design of a new field campaign in the frame of EUFAR Transnational Access (TA). TA provides access to either aircraft or instrumentation that are not otherwise

  16. Research on corrosion aspects of the advanced cold process canister

    International Nuclear Information System (INIS)

    Blackwood, D.J.; Hoch, A.R.; Naish, C.C.; Rance, A.

    1994-01-01

    The Advanced Cold Process Canister (ACPC) is a waste canister being developed jointly by SKB and TVO for the disposal of spent nuclear fuel. It comprises an outer copper canister, with a carbon steel canister inside. A concern regarding the use of the ACPC is that, in the unlikely event that the outer copper canister is penetrated, the anaerobic corrosion of the carbon steel container may result in the formation of hydrogen gas bubbles. These bubbles could disrupt the backfill, and thus increase water flow through the near field and the flux of radionuclides to the host geology. A number of factors that influence the rate at which hydrogen evolves as a result of the anaerobic corrosion of carbon steel in artificial granitic groundwaters have been investigated. A previously observed, time-dependent decline in the hydrogen evolution rate has been confirmed as being due to the production of magnetite film. Once the magnetite film is about 0.7-1.0 μm thick, the rate of hydrogen evolution reaches a steady state value. The pH and the ionic strength of the groundwater were both found to influence the long-term hydrogen evolution rate. The results of the experimental programme were used to update a model of the corrosion behaviour and hydrogen production from the Advanced Cold Process Canister. 36 figs, 5 tabs, 13 refs

  17. Research on chemical vapor deposition processes for advanced ceramic coatings

    Science.gov (United States)

    Rosner, Daniel E.

    1993-01-01

    Our interdisciplinary background and fundamentally-oriented studies of the laws governing multi-component chemical vapor deposition (VD), particle deposition (PD), and their interactions, put the Yale University HTCRE Laboratory in a unique position to significantly advance the 'state-of-the-art' of chemical vapor deposition (CVD) R&D. With NASA-Lewis RC financial support, we initiated a program in March of 1988 that has led to the advances described in this report (Section 2) in predicting chemical vapor transport in high temperature systems relevant to the fabrication of refractory ceramic coatings for turbine engine components. This Final Report covers our principal results and activities for the total NASA grant of $190,000. over the 4.67 year period: 1 March 1988-1 November 1992. Since our methods and the technical details are contained in the publications listed (9 Abstracts are given as Appendices) our emphasis here is on broad conclusions/implications and administrative data, including personnel, talks, interactions with industry, and some known applications of our work.

  18. Recent advances in applied research on DRO procedures.

    Science.gov (United States)

    Jessel, Joshua; Ingvarsson, Einar T

    2016-12-01

    Differential reinforcement of other behavior (DRO) has been applied to reduce problem behavior in various forms across different populations. We review DRO research from the last 5 years, with a focus on studies that enhance our understanding of the underlying mechanisms of DRO. We also discuss implications for practitioners and applied researchers. © 2016 Society for the Experimental Analysis of Behavior.

  19. NATO Advanced Research Workshop on Zinc Oxide as a Material for Micro- and Optoelectronic Applications

    CERN Document Server

    Nickel, Norbert H

    2005-01-01

    This volume reviews the latest experimental and theoretical studies in the field of ZnO. The chapters reflect the topics that were discussed during the NATO Advanced Research Workshop, which brought together researchers from Nato countries, Russia, Ukraine, and Kazakhstan to encourage cross fertilization and wider dissemination of the advances in this important research field. Fundamental issues such as growth of ZnO, structural, optical and electric properties, the role of the hydrogen and more were discussed.

  20. First 3 years of operation of RIACS (Research Institute for Advanced Computer Science) (1983-1985)

    Science.gov (United States)

    Denning, P. J.

    1986-01-01

    The focus of the Research Institute for Advanced Computer Science (RIACS) is to explore matches between advanced computing architectures and the processes of scientific research. An architecture evaluation of the MIT static dataflow machine, specification of a graphical language for expressing distributed computations, and specification of an expert system for aiding in grid generation for two-dimensional flow problems was initiated. Research projects for 1984 and 1985 are summarized.

  1. Report of the Review Committee on valuation of the research subjects in the fields of advanced science research

    International Nuclear Information System (INIS)

    2000-07-01

    On the basis of the JAERI's Basic Guidelines for the Research Evaluation Methods, etc. the Ad Hoc Review Committee composed of eight experts was set up under the Research Evaluation Committee of the JAERI in order to review the research theme completed in FY1998 and those planned for five years starting in FY2000 in the Advanced Science Research Center. The Ad Hoc Review Committee meeting was held on September 17, 1999. According to the review methods including review items, points of review and review criteria, determined by the Research Evaluation Committee, the review was conducted based on the research results/plan documents submitted in advance and presentations by the Research Group Leaders. The review report was submitted to the Research Evaluation Committee for further review and discussions in its meeting held on March 14, 2000. As a result, the Research Evaluation Committee acknowledged appropriateness of the review results. This report describes the review results. (author)

  2. Exploring the promises of intersectionality for advancing women's health research.

    Science.gov (United States)

    Hankivsky, Olena; Reid, Colleen; Cormier, Renee; Varcoe, Colleen; Clark, Natalie; Benoit, Cecilia; Brotman, Shari

    2010-02-11

    Women's health research strives to make change. It seeks to produce knowledge that promotes action on the variety of factors that affect women's lives and their health. As part of this general movement, important strides have been made to raise awareness of the health effects of sex and gender. The resultant base of knowledge has been used to inform health research, policy, and practice. Increasingly, however, the need to pay better attention to the inequities among women that are caused by racism, colonialism, ethnocentrism, heterosexism, and able-bodism, is confronting feminist health researchers and activists. Researchers are seeking new conceptual frameworks that can transform the design of research to produce knowledge that captures how systems of discrimination or subordination overlap and "articulate" with one another. An emerging paradigm for women's health research is intersectionality. Intersectionality places an explicit focus on differences among groups and seeks to illuminate various interacting social factors that affect human lives, including social locations, health status, and quality of life. This paper will draw on recently emerging intersectionality research in the Canadian women's health context in order to explore the promises and practical challenges of the processes involved in applying an intersectionality paradigm. We begin with a brief overview of why the need for an intersectionality approach has emerged within the context of women's health research and introduce current thinking about how intersectionality can inform and transform health research more broadly. We then highlight novel Canadian research that is grappling with the challenges in addressing issues of difference and diversity. In the analysis of these examples, we focus on a largely uninvestigated aspect of intersectionality research - the challenges involved in the process of initiating and developing such projects and, in particular, the meaning and significance of social

  3. Exploring the promises of intersectionality for advancing women's health research

    Directory of Open Access Journals (Sweden)

    Clark Natalie

    2010-02-01

    Full Text Available Abstract Women's health research strives to make change. It seeks to produce knowledge that promotes action on the variety of factors that affect women's lives and their health. As part of this general movement, important strides have been made to raise awareness of the health effects of sex and gender. The resultant base of knowledge has been used to inform health research, policy, and practice. Increasingly, however, the need to pay better attention to the inequities among women that are caused by racism, colonialism, ethnocentrism, heterosexism, and able-bodism, is confronting feminist health researchers and activists. Researchers are seeking new conceptual frameworks that can transform the design of research to produce knowledge that captures how systems of discrimination or subordination overlap and "articulate" with one another. An emerging paradigm for women's health research is intersectionality. Intersectionality places an explicit focus on differences among groups and seeks to illuminate various interacting social factors that affect human lives, including social locations, health status, and quality of life. This paper will draw on recently emerging intersectionality research in the Canadian women's health context in order to explore the promises and practical challenges of the processes involved in applying an intersectionality paradigm. We begin with a brief overview of why the need for an intersectionality approach has emerged within the context of women's health research and introduce current thinking about how intersectionality can inform and transform health research more broadly. We then highlight novel Canadian research that is grappling with the challenges in addressing issues of difference and diversity. In the analysis of these examples, we focus on a largely uninvestigated aspect of intersectionality research - the challenges involved in the process of initiating and developing such projects and, in particular, the meaning

  4. NATO Advanced Research Workshop on Terahertz and Mid Infrared Radiation

    CERN Document Server

    Pereira, Mauro F; Terahertz and Mid Infrared Radiation

    2011-01-01

    Terahertz (THz) and Mid-Infrared (MIR) radiation  (TERA-MIR) can be transmitted through nearly any material without causing biological harm. Novel and rapid methods of detection can be created with devices operation in these spectral ranges allowing scanning for weapons, detecting hidden explosives (including plastic landmines), controlling the quality of food and a host of other exciting applications.  This book focuses on mathematical and physical aspects of the field, on unifying these two spectral domains (THz and MIR) with regard to common sources, detectors, materials and applications, and on key interdisciplinary topics. The main THz and MIR source is the quantum cascade laser (QCL). Thus significant attention is paid to the challenge of turning this advanced technology into affordable commercial devices so as to exploit its enormous potential. However other alternatives to THz QCLs are also presented, e.g.  sub-terahertz imaging from avalanching GaAs bipolar transistors, Josephson junctions as THz ...

  5. Recent advances in research on unmanned aerial vehicles

    CERN Document Server

    Wang, Le; Yin, George

    2013-01-01

    A team of launched and coordinated Unmanned aerial vehicles (UAVs), requires advanced technologies in sensing, communication, computing, and control to improve their intelligence and robustness towards autonomous operations. To enhance reliability, robustness, and mission capability of a team of UAVs, a system-oriented and holistic approach is desirable in which all components and subsystems are considered in terms of their roles and impact on the entire system.  This volume aims to summarize the recent progress, identify challenges and opportunities, and develop new methodologies and systems on coordinated UAV control. A group of experts working in this area have contributed to this volume in several related aspects of autonomous control of networked UAVs. Their papers introduce new control methodologies, algorithms, and systems that address several important issues in developing intelligent, autonomous or semi-autonomous, networked systems for the next generation of UAVs. The papers share a common focus on...

  6. NATO Advanced Research Workshop on The Chemistry of Weathering

    CERN Document Server

    1985-01-01

    Several important developments in our understanding of the chemistry of weathering have occurred in the last few years: 1. There has been a major breakthrough in our understanding of the mechanisms controlling the kinetics of sil icate dissolution, and there have been major advances in computer modeling of weathering processes. 2. There has been a growing recognition of the importance of organic solutes in the weathering process, and hence of the inter-relationships between mineral weathering and the terrestrial ecosystem. 3. The impact of acid deposition ("acid rain") has been widely recognized. The processes by which acid deposition is neutral ized are closely related to the processes of normal chemical weathering; an understanding of the chemistry of weathering is thus essential for predicting the effects of acid deposition. 4. More high-qual ity data have become available on the chemical dynamics of smal I watersheds and large river systems, which represent the integrated effects of chemical weathering.

  7. Advances in Research of Polysaccharides in Cordyceps Species

    Directory of Open Access Journals (Sweden)

    Shi Zhong

    2009-01-01

    Full Text Available Cordyceps sinensis (Berk. Sacc. is one of the well-described fungi that has been used in traditional Chinese medicine for over 700 years. Fungal mycelia contain some polysaccharides that are responsible for their biological activity. C. sinensis has traditionally been cultivated on the high Tibetan plateau as a parasitic fungus growing on caterpillars. However, currently it is being cultivated on some insects and in artificial media. This article deals with the advances in the production, isolation and purification of Cordyceps polysaccharide (CP in recent years, as well as the structure elucidation and pharmacological action. The article also aims to provide some references for further application and exploitation in the future.

  8. Advancing sustainable development in Canada : policy issues and research needs

    International Nuclear Information System (INIS)

    Eliadis, P.; Slayen, S.

    2003-11-01

    This paper defined 7 policy-relevant issues that advance sustainable development in Canada. These were; (1) urban redesign, (2) freshwater management, (3) eco-region sustainability, (4) impacts of globalization on sustainable development in Canada, (5) designing signals and incentives that promote sustainable behaviour among citizens, (6) reducing the ecological burden of unsustainable lifestyles, and (7) international engagement in sustainable development. The authors questioned why these issues have not made greater progress, given that they have been on national and international agendas since 1972. They also questioned why it is so difficult to integrate environmental and economic signals. Finally, they examined whether enough ecological and political space can be provided to developing countries to achieve sustainable development while enhancing the standard of living in Canada and not threatening critical global systems. 173 refs

  9. Advance of molecular marker application in the tobacco research

    African Journals Online (AJOL)

    STORAGESEVER

    2008-12-29

    Dec 29, 2008 ... nature, codominant inheritance, easy access, easy and ... available DNA marker types employed in tobacco research, the second .... and organization of mitochondrial and chloroplast genomes ... maternal genome of tobacco.

  10. Chemical Safety Research Advances in Support of Lautenberg Act

    Science.gov (United States)

    EPA researchers are developing new ways to identify which chemicals to prioritize for further testing, to provide better access to information about chemicals, and to understand what potential risks chemicals may pose to humans and the environment.

  11. ATLAS program for advanced thermal-hydraulic safety research

    International Nuclear Information System (INIS)

    Song, Chul-Hwa; Choi, Ki-Yong; Kang, Kyoung-Ho

    2015-01-01

    Highlights: • Major achievements of the ATLAS program are highlighted in conjunction with both developing advanced light water reactor technologies and enhancing the nuclear safety. • The ATLAS data was shown to be useful for the development and licensing of new reactors and safety analysis codes, and also for nuclear safety enhancement through domestic and international cooperative programs. • A future plan for the ATLAS testing is introduced, covering recently emerging safety issues and some generic thermal-hydraulic concerns. - Abstract: This paper highlights the major achievements of the ATLAS program, which is an integral effect test program for both developing advanced light water reactor technologies and contributing to enhancing nuclear safety. The ATLAS program is closely related with the development of the APR1400 and APR"+ reactors, and the SPACE code, which is a best-estimate system-scale code for a safety analysis of nuclear reactors. The multiple roles of ATLAS testing are emphasized in very close conjunction with the development, licensing, and commercial deployment of these reactors and their safety analysis codes. The role of ATLAS for nuclear safety enhancement is also introduced by taking some examples of its contributions to voluntarily lead to multi-body cooperative programs such as domestic and international standard problems. Finally, a future plan for the utilization of ATLAS testing is introduced, which aims at tackling recently emerging safety issues such as a prolonged station blackout accident and medium-size break LOCA, and some generic thermal-hydraulic concerns as to how to figure out multi-dimensional phenomena and the scaling issue.

  12. Advancing Neuroscience Research in Africa: Invertebrate Species to the Rescue.

    Science.gov (United States)

    Balogun, Wasiu Gbolahan; Cobham, Ansa Emmanuel; Amin, Abdulbasit; Seeni, Azman

    2018-03-15

    Neuroscience research and training in many African countries are difficult due to funding and infrastructure deficit. This has resulted in few neuroscientists within Africa. However, invertebrates such as Drosophila and Caenorhabditis elegans could provide the perfect answer to these difficulties. These organisms are cheap, easy to handle and offer a comparable advantage over vertebrates in neuroscience research modeling because they have a simple nervous system and exhibit well-defined behaviors. Studies using invertebrates have helped to understand neurosciences and the complexes associated with it. If Africa wants to catch up with the rest of the world in neuroscience research, it needs to employ this innovative cost-effective approach in its research. To improve invertebrate neuroscience within the Africa continent, the authors advocated the establishment of invertebrate research centers either at regional or national level across Africa. Finally, there is also a need to provide public funding to consolidate the gains that have been made by not-for-profit international organizations over the years. Copyright © 2018 IBRO. Published by Elsevier Ltd. All rights reserved.

  13. The advanced fuel cycle initiative: the future path for advanced spent fuel treatment and transmutation research in the United States

    International Nuclear Information System (INIS)

    Herczeg, J.W.

    2003-01-01

    The U. S. Department of Energy (DOE) has invested over USD 100 million in transmutation research and development over the past three years. The programme has evolved from an accelerator based transmutation programme to a multi-tier reactor and accelerator based programme. These changes have resulted in a significant re-focus of the research and development programme as well as a name change to reflect the new direction. The Advanced Accelerator Application (AAA) programme is now renamed the Advanced Fuel Cycle Initiative (AFCI). Research completed by the AAA programme in Fiscal Year 2002 points to a multi-phased AFCI Programme consisting of two elements that would be conducted in parallel as part of an integrated research effort: an intermediate-term technology element (AFCI Series One), which emphasises advanced technical enhancements to the current commercial nuclear power infrastructure; and a long term technology element (AFCI Series Two), which will require the introduction of next-generation nuclear energy systems to reduce the toxicity of nuclear waste. (author)

  14. Eco-informatics for decision makers advancing a research agenda

    Science.gov (United States)

    Cushing, J.B.; Wilson, T.; Brandt, L.; Gregg, V.; Spengler, S.; Borning, A.; Delcambre, L.; Bowker, G.; Frame, M.; Fulop, J.; Hert, C.; Hovy, E.; Jones, J.; Landis, E.; Schnase, J.L.; Schweik, C.; Sonntag, W.; ,

    2005-01-01

    Resource managers often face significant information technology (IT) problems when integrating ecological or environmental information to make decisions. At a workshop sponsored by the NSF and USGS in December 2004, university researchers, natural resource managers, and information managers met to articulate IT problems facing ecology and environmental decision makers. Decision making IT problems were identified in five areas: 1) policy, 2) data presentation, 3) data gaps, 4) tools, and 5) indicators. To alleviate those problems, workshop participants recommended specific informatics research in modeling and simulation, data quality, information integration and ontologies, and social and human aspects. This paper reports the workshop findings, and briefly compares these with research that traditionally falls under the emerging eco-informatics rubric. ?? Springer-Verlag Berlin Heidelberg 2005.

  15. Artificial Sight Basic Research, Biomedical Engineering, and Clinical Advances

    CERN Document Server

    Humayun, Mark S; Chader, Gerald; Greenbaum, Elias

    2008-01-01

    Artificial sight is a frontier area of modern ophthalmology combining the multidisciplinary skills of surgical ophthalmology, biomedical engineering, biological physics, and psychophysical testing. Many scientific, engineering, and surgical challenges must be surmounted before widespread practical applications can be realized. The goal of Artificial Sight is to summarize the state-of-the-art research in this exciting area, and to describe some of the current approaches and initiatives that may help patients in a clinical setting. The Editors are active researchers in the fields of artificial sight, biomedical engineering and biological physics. They have received numerous professional awards and recognition for their work. The artificial sight team at the Doheny Eye Institute, led by Dr. Mark Humayun, is a world leader in this area of biomedical engineering and clinical research. Key Features Introduces and assesses the state of the art for a broad audience of biomedical engineers, biophysicists, and clinical...

  16. Advances, gaps, and future prospects in biological soil crust research

    Science.gov (United States)

    Weber, Bettina; Büdel, Burkhard; Belnap, Jayne

    2017-04-01

    Research progress has led to the understanding that biological soil crusts (biocrusts) are often complete miniature ecosystems comprising a variety of photosynthesizers (cyanobacteria, algae, lichens, bryophytes), decomposers like bacteria, fungi, and archaea, and heterotrophic organisms, like protozoa, nematodes, and microarthropods feeding on them. Biocrusts are one of the oldest terrestrial ecosystems, playing central roles in the structure and functioning of dryland ecosystems and presumably also influencing global biogeochemical cycles. On the other hand, biocrusts have been shown to be highly sensitive to global change, being easily destroyed by mechanical disturbance and severely threatened by minor changes in climate patterns. Despite the large increase in biocrust research, we still see major knowledge gaps which need to be tackled. Considering biodiversity studies, there are major regions of potential biocrust occurrence, where hardly any studies have been conducted. Molecular identification techniques are increasingly employed, but genetically characterized entities need to be linked with morphologically identified organisms to identify their ecological roles. Although there is a large body of research on the role of biocrusts in water and nutrient budgets, we are still far from closing the overall cycles. Results suggest that not all mechanisms have been identified, yet, leading to sometimes contradictory results between different studies. Knowledge on how to minimize impact to biocrusts during surface-disturbing activities has hardly been gained, and despite research efforts, instructions on effective biocrust restoration are still exemplary. In order to fill these research gaps, novel scientific approaches are needed. We expect that global research networks could be extremely helpful to answer scientific questions by tackling them within different regions, utilizing the same methodological techniques. Global networks could also be used for long

  17. Storing in clay beds? What about research advancement?

    International Nuclear Information System (INIS)

    Lebon, P.

    2006-01-01

    The concept of underground disposal of toxic or radioactive materials is based on the idea that some geologic formations are capable to ensure the confinement of waste packages over very long periods of time by limiting the water influx towards the toxic elements and by fixing up those in solution. This paper presents the state-of-the-art about the researches on manufactured clays (nature, properties and conditioning) and about the researches on clay beds with the example of the Meuse/Haute-Marne (France) underground laboratory (geologic history, lithology, permeability, rock mechanics). (J.S.)

  18. Cooperative Research and Development for Advanced Microturbines Program on Advanced Integrated Microturbine System

    Energy Technology Data Exchange (ETDEWEB)

    Michael J. Bowman

    2007-05-30

    The Advanced Integrated Microturbine Systems (AIMS) project was kicked off in October of 2000 to develop the next generation microturbine system. The overall objective of the project was to develop a design for a 40% electrical efficiency microturbine system and demonstrate many of the enabling technologies. The project was initiated as a collaborative effort between several units of GE, Elliott Energy Systems, Turbo Genset, Oak Ridge National Lab and Kyocera. Since the inception of the project the partners have changed but the overall direction of the project has stayed consistent. The project began as a systems study to identify design options to achieve the ultimate goal of 40% electrical efficiency. Once the optimized analytical design was identified for the 40% system, it was determined that a 35% efficient machine would be capable of demonstrating many of the advanced technologies within the given budget and timeframe. The items that would not be experimentally demonstrated were fully produced ceramic parts. However, to understand the requirements of these ceramics, an effort was included in the project to experimentally evaluate candidate materials in representative conditions. The results from this effort would clearly identify the challenges and improvement required of these materials for the full design. Following the analytical effort, the project was dedicated to component development and testing. Each component and subsystem was designed with the overall system requirements in mind and each tested to the fullest extent possible prior to being integrated together. This method of component development and evaluation helps to minimize the technical risk of the project. Once all of the components were completed, they were assembled into the full system and experimentally evaluated.

  19. Current Knowledge and Recent Advances in Marine Dinoflagellate Transcriptomic Research

    Directory of Open Access Journals (Sweden)

    Muhamad Afiq Akbar

    2018-02-01

    Full Text Available Dinoflagellates are essential components in marine ecosystems, and they possess two dissimilar flagella to facilitate movement. Dinoflagellates are major components of marine food webs and of extreme importance in balancing the ecosystem energy flux in oceans. They have been reported to be the primary cause of harmful algae bloom (HABs events around the world, causing seafood poisoning and therefore having a direct impact on human health. Interestingly, dinoflagellates in the genus Symbiodinium are major components of coral reef foundations. Knowledge regarding their genes and genome organization is currently limited due to their large genome size and other genetic and cytological characteristics that hinder whole genome sequencing of dinoflagellates. Transcriptomic approaches and genetic analyses have been employed to unravel the physiological and metabolic characteristics of dinoflagellates and their complexity. In this review, we summarize the current knowledge and findings from transcriptomic studies to understand the cell growth, effects on environmental stress, toxin biosynthesis, dynamic of HABs, phylogeny and endosymbiosis of dinoflagellates. With the advancement of high throughput sequencing technologies and lower cost of sequencing, transcriptomic approaches will likely deepen our understanding in other aspects of dinoflagellates’ molecular biology such as gene functional analysis, systems biology and development of model organisms.

  20. Research and development of advanced robots for nuclear power plants

    International Nuclear Information System (INIS)

    Tsukune, Hideo; Hirukawa, Hirohisa; Kitagaki, Kosei; Liu, Yunhui; Onda, Hiromu; Nakamura, Akira

    1994-01-01

    Social and economic demands have been pressing for automation of inspection tasks, maintenance and repair jobs of nuclear power plants, which are carried out by human workers under circumstances with high radiation level. Since the plants are not always designed for introduction of automatic machinery, sophisticated robots shall play a crucial role to free workers from hostile environments. We have been studying intelligent robot systems and regarded nuclear industries as one of the important application fields where we can validate the feasibility of the methods and systems we have developed. In this paper we firstly discuss on the tasks required in nuclear power plants. Secondly we introduce current status of R and D on special purpose robots, versatile robots and intelligent robots for automatizing the tasks. Then we focus our discussions on three major functions in realizing robotized assembly tasks under such unstructured environments as in nuclear power plants; planning, vision and manipulation. Finally we depict an image of a prototype robot system for nuclear power plants based on the advanced functions. (author) 64 refs

  1. Research advances in proton beam therapy for hepatocellular carcinoma

    Directory of Open Access Journals (Sweden)

    DAI Shuyang

    2013-10-01

    Full Text Available Hepatocellular carcinoma (HCC, one of the most common malignancies with high prevalence and mortality rate, usually results in poor prognosis and limited survival. A comprehensive analysis on the number and location of tumors, Child-Pugh grade, and Barcelona Clinic Liver Cancer stage will help the development of suitable treatment programs and improve prediction of prognosis. A majority of patients are complicated by cirrhosis, enlarged tumor, multiple lesions, vascular invasion, and even cancer embolus in the portal vein. With the growth of knowledge about the radiation tolerance of normal tissue and the advances in radiotherapy techniques, radiotherapy has become an important tool for step-down therapy and adjuvant therapy for liver cancer. Proton beam therapy (PBT is emerging as a novel radiotherapy for the management of HCC, which, benefiting from the effect of Bragg Peak from PBT, effectively decreases the toxicity of traditional radiotherapies to the liver and does little harm to the uninvolved liver tissue or the surrounding structures while intensifying the destruction in targeted malignant lesions. Furthermore, several previous studies on the treatment of HCC with PBT revealed excellent local control. The distinctive biophysical attributes of PBT in the treatment of HCC, as well as the available literature regarding clinical outcomes and toxicity of using PBT for HCC, are reviewed. Current evidence provides limited indications for PBT, which suggests that further study on the relationship between liver function and PBT is required to gain further insight into its indication and standardization.

  2. [Research advances in eco-toxicological diagnosis of soil pollution].

    Science.gov (United States)

    Liu, Feng; Teng, Hong-Hui; Ren, Bai-Xiang; Shi, Shu-Yun

    2014-09-01

    Soil eco-toxicology provides a theoretical basis for ecological risk assessment of contaminated soils and soil pollution control. Research on eco-toxicological effects and molecular mechanisms of toxic substances in soil environment is the central content of the soil eco-toxicology. Eco-toxicological diagnosis not only gathers all the information of soil pollution, but also provides the overall toxic effects of soil. Therefore, research on the eco-toxicological diagnosis of soil pollution has important theoretical and practical significance. Based on the research of eco-toxicological diagnosis of soil pollution, this paper introduced some common toxicological methods and indicators, with the advantages and disadvantages of various methods discussed. However, conventional biomarkers can only indicate the class of stress, but fail to explain the molecular mechanism of damage or response happened. Biomarkers and molecular diagnostic techniques, which are used to evaluate toxicity of contaminated soil, can explore deeply detoxification mechanisms of organisms under exogenous stress. In this paper, these biomarkers and techniques were introduced systematically, and the future research trends were prospected.

  3. Parent-Child Play across Cultures: Advancing Play Research

    Science.gov (United States)

    Roopnarine, Jaipaul L.; Davidson, Kimberly L.

    2015-01-01

    In this article, the authors argue for a greater understanding of children's play across cultures through better integration of scientific thinking about the developed and developing societies, through consideration of socialization beliefs and goals, and, finally, through the use of more complex models in research investigations. They draw on…

  4. Performance Evaluation of Metallic Dispersion Fuel for Advanced Research Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Ryu, Ho Jin; Park, Jong Man; Kim, Chang Kyu; Chae, Hee Taek; Song, Kee Chan [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Kim, Yeon Soo [Argonne National Laboratory, New York (United States)

    2007-07-01

    Uranium alloys with a high uranium density has been developed for high power research reactor fuel using low-enriched uranium (LEU). U-Mo alloys have been developed as candidate fuel material because of excellent irradiation behavior. Irradiation behavior of U-Mo/Al dispersion fuel has been investigated to develop high performance research reactor fuel as RERTR international research program. While plate-type and rod-type dispersion fuel elements are used for research reactors, HANARO uses rod-type dispersion fuel elements. PLATE code is developed by Argonne National Laboratory for the performance evaluation of plate-type dispersion fuel, but there is no counterpart for rod-type dispersion fuel. Especially, thermal conductivity of fuel meat decreases during the irradiation mainly because of interaction layer formation at the interface between the U-Mo fuel particle and Al matrix. The thermal conductivity of the interaction layer is not as high as the Al matrix. The growth of interaction layer is interactively affected by the temperature of fuel because it is associated with a diffusion reaction which is a thermally activated process. It is difficult to estimate the temperature profile during irradiation test due to the interdependency of fuel temperature and thermal conductivity changed by interaction layer growth. In this study, fuel performance of rod-type U-Mo/Al dispersion fuels during irradiation tests were estimated by considering the effect of interaction layer growth on the thermal conductivity of fuel meat.

  5. 1973 Advances in Socio-Dental Research. Vol. 1.

    Science.gov (United States)

    Goetz, John B., Ed.

    This publication is a collection of abstracts from volumes 6 and 7 (1971 and 1972) of "Oral Research Abstracts," selected because the abstracts contain information relating one of the social sciences with dentistry. The compilation is intended to be useful to epidemiologists, public health workers, and all those who have an interest in…

  6. The Impact of Research and Technological Advances on Dental Education.

    Science.gov (United States)

    Loe, Harald

    1981-01-01

    To arrive at a learning situation conducive to a scientific approach in dental school teaching of diagnosis, treatment, prescription, and judgment of prognosis, it is necessary to strengthen the scientific environment in dental schools, increase scientifically trained faculty, and guarantee student involvement in research. (MLW)

  7. Journal of Agriculture and Social Research (JASR): Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  8. Eastern Africa Social Science Research Review: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  9. ADVANCED COMPOSITES TECHNOLOGY CASE STUDY AT NASA LANGLEY RESEARCH CENTER

    Science.gov (United States)

    This report summarizes work conducted at the National Aeronautics and Space Administration's Langley Research Center (NASA-LaRC) in Hampton, VA, under the U.S. Environmental Protection Agency’s (EPA) Waste Reduction Evaluations at Federal Sites (WREAFS) Program. Support for...

  10. Research Review of the Institute of African Studies: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  11. Ugandan-Canadian partnership advances research on disability ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    20 août 2012 ... In Uganda, statistics show that 20% of the country's population has some form of physical disability. Despite these numbers, little research has been conducted to provide a window into the lives of people with disabilities.

  12. Journal of Research in National Development: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  13. Journal of Agricultural Research and Development: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  14. Journal of Civil Engineering Research and Practice: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  15. Journal of Applied Chemistry and Agricultural Research: Advanced ...

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  16. Savannah Journal of Medical Research and Practice: Advanced ...

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  17. Ugandan-Canadian partnership advances research on disability ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-06-21

    Jun 21, 2016 ... English · Français ... Their work generated a baseline of qualitative research data and determined six key areas for further study and advocacy. ... the ramp's steepness and the step up at the bottom make it difficult to use.​​ ...

  18. Advancement in Perfluoroalkyl Research Hampered by Analytical Challenges

    NARCIS (Netherlands)

    Martin, J.W.; Kannan, K.; Berger, U.; de Voogt, P.; Field, J.; Giesy, J.P.; Harner, T.; Muir, D.C.G.; Scott, B.; Kaiser, M.; Jarnberg, U.; Jones, K.C.; Mabury, S.A.; Schroeder, H.; Simcik, M.; Sottani, C.; Van Bavel, B.; Karrman, A.; Lindstrom, G.; Van Leeuwen, S.

    2004-01-01

    The growing concern over these organohalogens, some of which have been found in human blood and appear to be widespread in the environment, led researchers to gather in Hamburg, Germany, in 2003 to evaluate the current state of methods to analyze for the organic contaminants. Jonathan Martin of the

  19. Annals of Medical and Health Sciences Research: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  20. Advancing Massage Therapy Research Competencies: Dimensions for Thought and Action.

    Science.gov (United States)

    Hymel, Glenn M.

    Two major developments in the therapeutic massage and bodywork profession have recently brought to the forefront the issue of research competencies. The profession has been called to a potentially heightened level of credibility. One challenge to the profession's development is that of coordinating the various curricular, instructional,…

  1. NREL at 40: Driving Advanced Energy Research | NREL

    Science.gov (United States)

    of a woman standing on top of a wind turbine NREL's innovative research leads to job creation and over its 40 year history. Working with our partners in industry and academia, NREL delivers the George H.W. Bush elevated the institute to national lab status. Laboratory History In 1977, NREL started

  2. Transportation and Aging: A Research Agenda for Advancing Safe Mobility

    Science.gov (United States)

    Dickerson, Anne E.; Molnar, Lisa J.; Eby, David W.; Adler, Geri; Bedard, Michel; Berg-Weger, Marla; Classen, Sherrilene; Foley, Daniel; Horowitz, Amy; Kerschner, Helen; Page, Oliver; Silverstein, Nina M.; Staplin, Loren; Trujillo, Leonard

    2007-01-01

    Purpose: We review what we currently know about older driver safety and mobility, and we highlight important research needs in a number of key areas that hold promise for achieving the safety and mobility goals for the aging baby boomers and future generations of older drivers. Design and Methods: Through the use of a framework for transportation…

  3. Advanced laser fusion target fabrication research and development proposal

    International Nuclear Information System (INIS)

    Stupin, D.M.; Fries, R.J.

    1979-05-01

    A research and development program is described that will enable the fabrication of 10 6 targets/day for a laser fusion prototype power reactor in 2007. We give personnel and cost estimates for a generalized laser fusion target that requires the development of several new technologies. The total cost of the program between 1979 and 2007 is $362 million in today's dollars

  4. Science, Technology and Arts Research Journal: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  5. Performance Evaluation of Metallic Dispersion Fuel for Advanced Research Reactors

    International Nuclear Information System (INIS)

    Ryu, Ho Jin; Park, Jong Man; Kim, Chang Kyu; Chae, Hee Taek; Song, Kee Chan; Kim, Yeon Soo

    2007-01-01

    Uranium alloys with a high uranium density has been developed for high power research reactor fuel using low-enriched uranium (LEU). U-Mo alloys have been developed as candidate fuel material because of excellent irradiation behavior. Irradiation behavior of U-Mo/Al dispersion fuel has been investigated to develop high performance research reactor fuel as RERTR international research program. While plate-type and rod-type dispersion fuel elements are used for research reactors, HANARO uses rod-type dispersion fuel elements. PLATE code is developed by Argonne National Laboratory for the performance evaluation of plate-type dispersion fuel, but there is no counterpart for rod-type dispersion fuel. Especially, thermal conductivity of fuel meat decreases during the irradiation mainly because of interaction layer formation at the interface between the U-Mo fuel particle and Al matrix. The thermal conductivity of the interaction layer is not as high as the Al matrix. The growth of interaction layer is interactively affected by the temperature of fuel because it is associated with a diffusion reaction which is a thermally activated process. It is difficult to estimate the temperature profile during irradiation test due to the interdependency of fuel temperature and thermal conductivity changed by interaction layer growth. In this study, fuel performance of rod-type U-Mo/Al dispersion fuels during irradiation tests were estimated by considering the effect of interaction layer growth on the thermal conductivity of fuel meat

  6. UPDATE ON DEVELOPMENT OF NUDGING FDDA FOR ADVANCED RESEARCH WRF

    Science.gov (United States)

    A nudging-based four-dimensional data assimilation (FDDA) system is being developed for the Weather Research and Forecasting (WRF) Model. This effort represents a collaboration between The Pennsylvania State University (i.e., Penn State), the National Center for Atmospheric Rese...

  7. Advanced Marginality as a comparative research strategy in praxis:

    DEFF Research Database (Denmark)

    Larsen, Troels Schultz

    2018-01-01

    and homology. These concepts are applied as the foundation of a comparative research design comprising three necessary and interconnected analytical moments linking reflexivity, theory and empirical analysis. Empirically this strategy and design is confronted in the case of four Danish “Grey belt” housing...

  8. Nigerian Journal of Soil and Environmental Research: Advanced ...

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  9. Advance of molecular marker application in the tobacco research ...

    African Journals Online (AJOL)

    Tobacco (Nicotiana spp.) is one of the most important commercial crops in the world. During the last two decades, molecular markers have entered the scene of genetic improvement in different fields of agricultural research. The principles and characteristics of several molecular markers such as RFLP, RAPD, AFLP, ...

  10. FY2011 Annual Progress Report for Advanced Combustion Engine Research and Development

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2011-12-01

    Annual Progress Report for the Advanced Combustion Engine Research and Development (R&D) subprogram supporting the mission of the Vehicle Technologies Program by removing the critical technical barriers to commercialization of advanced internal combustion engines (ICEs) for passenger and commercial vehicles that meet future federal emissions regulations.

  11. Advancing the management of Obstructive Airways Diseases through Translational Research

    DEFF Research Database (Denmark)

    Porsbjerg, Celeste; Sverrild, Asger; Baines, Katherine J

    2018-01-01

    Obstructive airways diseases (OAD) represent a huge burden of illness worldwide, and in spite of the development of effective therapies, significant morbidity and mortality related to asthma and COPD still remains. Over the past decade, our understanding of OAD has improved vastly, and novel...... treatments have evolved. This evolution is the result of successful translational research, which has connected clinical presentations of OAD and underlying disease mechanisms, thereby enabling the development of targeted treatments. The next challenge of translational research will be to position...... these novel treatments for OAD for optimal clinical use. At the same time, there is great potential in these treatments providing even better insights into disease mechanisms in OAD, by studying the effects of blocking individual immunological pathways. To optimise this potential, there is a need to ensure...

  12. Two Micron Laser Technology Advancements at NASA Langley Research Center

    Science.gov (United States)

    Singh, Upendra N.

    2010-01-01

    An Independent Laser Review Panel set up to examine NASA s space-based lidar missions and the technology readiness of lasers appropriate for space-based lidars indicated a critical need for an integrated research and development strategy to move laser transmitter technology from low technical readiness levels to the higher levels required for space missions. Based on the review, a multiyear Laser Risk Reduction Program (LRRP) was initiated by NASA in 2002 to develop technologies that ensure the successful development of the broad range of lidar missions envisioned by NASA. This presentation will provide an overview of the development of pulsed 2-micron solid-state laser technologies at NASA Langley Research Center for enabling space-based measurement of wind and carbon dioxide.

  13. Advances in mechanism research of pain in Parkinson's disease

    Directory of Open Access Journals (Sweden)

    Hui LIU

    2017-09-01

    Full Text Available Parkinson's disease (PD, a neurodegenerative disease, is very common in middle aged and older people. There are two kinds of symptoms: motor symptoms and non - motor symptoms (NMS. Pain, a commonly reported NMS of PD, can significantly affect the quality of life, thus causing more attention. However, mechanisms of pain in PD is not clear, and need to be further researched. DOI: 10.3969/j.issn.1672-6731.2017.08.006

  14. Research advances in the pathogenesis of nonalcoholic fatty liver disease

    Directory of Open Access Journals (Sweden)

    WANG Hu

    2017-04-01

    Full Text Available Nonalcoholic fatty liver disease (NAFLD has been developing rapidly in recent years and has become one of the most common liver diseases. However, its pathogenesis remains unclear, and there are no widely accepted therapeutic regimens. NAFLD has a complex pathogenesis with multiple factors involved, including insulin resistance, oxidative stress, bile acid metabolic disorders, and autophagy. This article reviews the pathogenesis of NAFLD in order to provide a reference for further research and clinical treatment in the future.

  15. Status, Trends, and Advances in Earthworm Research and Vermitechnology

    International Nuclear Information System (INIS)

    Karmegam, N.; Kale, R.D.; Kale, R.D.; Daniel, T.; Alam, M.N.; Rodriguez, M.G.

    2010-01-01

    In this special issue reflect the developments in the fields of earthworm research and vermitechnology. Charles Darwins observation on earthworms is a milestone in understanding the soil biology and enormous contribution to some aspects of the genesis of humus and of its role in soils. Earthworms are the best known soil inhabiting animals commonly called friends of farmers due to the beneficial role they play in soil. The research on earthworms has gained importance in India as well as in other countries. In the year 1981, an international symposium entitled Earthworm Ecology: Darwin to Vermiculture was held at Cumbria, UK, to commemorate the centenary celebration of Darwins book The Formation of Vegetable Mould through the Action of Worms, with Observations on Their Habits that was published in 1881 by Murray, London, UK. In the year 2000, Vermillenium-an international workshop and symposium- was held at Kalamazoo, USA, to realize the progress achieved in this field after a decade (since 1991). Recently, Ninth International Symposium on Earthworm Ecology (ISEE-9) that was held at Xalapa, Mexico, during the 5th to 10th of September 2010 clearly proved the importance of earthworms and vermitechnology by the participation of scientists from different countries. About 300 papers were received from the researchers across the world

  16. Gynecologic ultrasonography: recent advances and research in various technical modalities

    Directory of Open Access Journals (Sweden)

    Juraj Drobný

    2010-10-01

    Full Text Available Juraj DrobnýFirst Department of Obstetrics and Gynaecology, St. Cyril and Method University Hospital, Bratislava, Slovak RepublicAbstract: This paper reviews clinical research in gynecologic sonography, focussing on uterine cavity lesions, endometrial abnormalities and adnexal masses (including endometriosis, and ectopic pregnancy. For each topic, detection of sonographic pathologic features and sonographic mode are discussed, as well as the latest applications of sonodiagnostic methods, and relevant topics in clinical research. A new approach to evaluation of sonographic structures can be seen, including for borderline mucinous and serous ovarian tumors, in mean gray value, evaluation of grade of tissue echogenicity, evaluation of intact endometrial midline echo in ectopic pregnancy, and application of gel instillation sonography. Novel sonographic three-dimensional modalities, such as virtual navigation through three orthogonal planes, multislice tomosonography, volumetry by a virtual organ computer-aided analysis system, three-dimensional power Doppler, and space reconstruction of structures enable gynecologic diagnoses to be made more exactly. Clinical research investigates different sonographic features in benign and malignant gynecologic pathology. For studies of typical signs of benign uterine fibroids, endometrial volume, and vascularization of malignant endometrial tumors, as well as typical benign adnexal structures, the ovarian crescent sign were performed. At this time, no exact sonographic features for distinguishing between benign and malignant gynecologic tumors are available.Keywords: sonography, uterine cavity lesions, endometrial abnormalities, adnexal masses

  17. Basic and clinical research advances in ischemic stroke

    Directory of Open Access Journals (Sweden)

    Yuan-yuan MA

    2018-01-01

    Full Text Available Stroke is the most common cerebrovascular disease worldwide, which seriously affects life quality of survivals and results in huge economic burden of families and society. In terms of clinical treatment for ischemic stroke, apart from thrombolytic therapy with recombinant tissue-type plasminogen activator (rt-PA, the occurrence and successful application of endovascular thrombectomy in patients of ischemic stroke is a major breakthrough. Meanwhile, many novel clinical drugs for ischemic stroke therapy have entered into clinical trials. Most of basic and clinical researches have showed promising results in ischemic stroke therapy. This review mainly summarizes the progress of research during the period of Twelfth Five-Year Plan for National Economic and Social Development on treatment of ischemic stroke, including omics technologies, gene therapy, microRNA (miRNA interference and stem cell therapy. Stem cell therapy has shown great potential since many clinical trials have been completed or are ongoing. The development and mutual transformation of basic and clinical research will provide valuable and comprehensive information for the precise treatment of ischemic stroke.

  18. The Advanced Interdisciplinary Research Laboratory: A Student Team Approach to the Fourth-Year Research Thesis Project Experience

    Science.gov (United States)

    Piunno, Paul A. E.; Boyd, Cleo; Barzda, Virginijus; Gradinaru, Claudiu C.; Krull, Ulrich J.; Stefanovic, Sasa; Stewart, Bryan

    2014-01-01

    The advanced interdisciplinary research laboratory (AIRLab) represents a novel, effective, and motivational course designed from the interdisciplinary research interests of chemistry, physics, biology, and education development faculty members as an alternative to the independent thesis project experience. Student teams are assembled to work…

  19. Experimental research on passive residual heat remove system for advanced PWR

    International Nuclear Information System (INIS)

    Huang Yanping; Zhuo Wenbin; Yang Zumao; Xiao Zejun; Chen Bingde

    2003-01-01

    The experimental and qualified results of MISAP in the research of passive residual heat remove system of advanced PWR performed in the Bubble physics and natural circulation laboratory in Nuclear Power Institute of China in the past ten years is overviewed. Further researches for engineering research and design are also suggested

  20. Sustainability of evidence-based healthcare: research agenda, methodological advances, and infrastructure support.

    Science.gov (United States)

    Proctor, Enola; Luke, Douglas; Calhoun, Annaliese; McMillen, Curtis; Brownson, Ross; McCrary, Stacey; Padek, Margaret

    2015-06-11

    Little is known about how well or under what conditions health innovations are sustained and their gains maintained once they are put into practice. Implementation science typically focuses on uptake by early adopters of one healthcare innovation at a time. The later-stage challenges of scaling up and sustaining evidence-supported interventions receive too little attention. This project identifies the challenges associated with sustainability research and generates recommendations for accelerating and strengthening this work. A multi-method, multi-stage approach, was used: (1) identifying and recruiting experts in sustainability as participants, (2) conducting research on sustainability using concept mapping, (3) action planning during an intensive working conference of sustainability experts to expand the concept mapping quantitative results, and (4) consolidating results into a set of recommendations for research, methodological advances, and infrastructure building to advance understanding of sustainability. Participants comprised researchers, funders, and leaders in health, mental health, and public health with shared interest in the sustainability of evidence-based health care. Prompted to identify important issues for sustainability research, participants generated 91 distinct statements, for which a concept mapping process produced 11 conceptually distinct clusters. During the conference, participants built upon the concept mapping clusters to generate recommendations for sustainability research. The recommendations fell into three domains: (1) pursue high priority research questions as a unified agenda on sustainability; (2) advance methods for sustainability research; (3) advance infrastructure to support sustainability research. Implementation science needs to pursue later-stage translation research questions required for population impact. Priorities include conceptual consistency and operational clarity for measuring sustainability, developing evidence

  1. NATO Advanced Research Workshop on New Materials for Thermoelectric Applications

    CERN Document Server

    Hewson, Alex

    2013-01-01

    Thermoelectric devices could play an important role in making efficient use of our energy resources but their efficiency would need to be increased for their wide scale application. There is a multidisciplinary search for materials with an enhanced thermoelectric responses for use in such devices. This volume covers the latest ideas and developments in this research field, covering topics ranging from the fabrication and characterization of new materials, particularly those with strong electron correlation, use of nanostructured, layered materials and composites, through to theoretical work to gain a deeper understanding of thermoelectric behavior. It should be a useful guide and stimulus to all working in this very topical field.

  2. Advances and Research Directions in Data-Warehousing Technology

    Directory of Open Access Journals (Sweden)

    Mukesh Mohania

    1999-11-01

    Full Text Available Information is one of the most valuable assets of an organisation and when used properly can assist in intelligent decision making that can significantly improve the functioning of an organisation. Data Warehousing is a recent technology that allows information to be easily and efficiently accessed for decision-making activities by collecting data from many operational, legacy and possibly heterogeneous data sources. On-Line Analytical Processing (OLAP tools are well-suited for complex data analysis, such as multi-dimensional data analysis, and to assist in decision support activities while data mining tools take the process one step further and actively search the data for patterns and hidden knowledge in the data held in the warehouse. Many organisations are building, or are planning to develop, a data warehouse for their operational and decision support needs. In this paper, we present an overview of data warehousing, multi-dimensional databases, OLAP and data mining technology and discuss the directions of current research in the area. We also discuss recent developments in data warehouse modelling, view selection and maintenance, indexing schemes, parallel query processing and data mining issues. A number of technical issues for exploratory research are presented and possible solutions are also discussed.

  3. Research on advanced system safety assessment procedures (III)

    International Nuclear Information System (INIS)

    Suzuki, Kazuhiko; Shimada, Yukiyasu

    2000-03-01

    Though HAZOP is recognized as the useful safety assessment method, it requires a labor-intensive and time-consuming process. So recently computer-aided HAZOP has been proposed. The research report in 1999 (PNC TJ1400 99-003) presented HAZOP system based on the plant component malfunctions basic models. By using this basic model, not only state malfunction of component but also the consequence to external circumstance can be assessed. G2, which is an excellent object-oriented developer tool in GUI (Graphical User Interface), was used as a tool for developing the system. By using the graphical editor in the system, the user can carry out HAZOP easily. The purpose of this research is to improve the ability of the HAZOP system to obtain a more detailed HAZOP results. HAZOP is carried out according to the fault propagation of component level and the one of plant level based on plant component malfunctions basic models. Furthermore, the HAZOP system which can do the cause and effect analysis in detail intended for the component which processes two or more materials is developed. It is possible to carry out HAZOP for various plants by newly adding material information to the knowledge base. We have applied this system to the Nuclear Reprocessing Facilities to demonstrate the utilities of developing system. (author)

  4. Advances in operational safety and severe accident research

    Energy Technology Data Exchange (ETDEWEB)

    Simola, K. [VTT Automation (Finland)

    2002-02-01

    A project on reactor safety was carried out as a part of the NKS programme during 1999-2001. The objective of the project was to obtain a shared Nordic view of certain key safety issues related to the operating nuclear power plants in Finland and Sweden. The focus of the project was on selected central aspects of nuclear reactor safety that are of common interest for the Nordic nuclear authorities, utilities and research bodies. The project consisted of three sub-projects. One of them concentrated on the problems related to risk-informed deci- sion making, especially on the uncertainties and incompleteness of probabilistic safety assessments and their impact on the possibilities to use the PSA results in decision making. Another sub-project dealt with questions related to maintenance, such as human and organisational factors in maintenance and maintenance management. The focus of the third sub-project was on severe accidents. This sub-project concentrated on phenomenological studies of hydrogen combustion, formation of organic iodine, and core re-criticality due to molten core coolant interaction in the lower head of reactor vessel. Moreover, the current status of severe accident research and management was reviewed. (au)

  5. [Research advances in ecological stoichiometry of marine plankton].

    Science.gov (United States)

    Chen, Lei; Li, Chao-Lun

    2014-10-01

    Ecological stoichiometry can be simply defined as: The biology of elements from molecules to the biosphere, which spans all levels of the environment and of the life. It's a new idea to build a unified theory and becomes an inevitable trend to develop the ecological science. Marine ecosystems, which contribute to 50% of the biosphere biomass, are the important component of the global biogeochemical cycles. Marine zooplankton plays an important role in the material circulation and energy flow of marine ecosystems and serves as a connecting link between the preceding and the following in a more precise understanding of the key elemental cycles. However, research on ecological stoichiometry of marine plankton is fragmentary and rare. This article summarized the ecological phenomena and mechanisms of limiting elements affecting marine plankton, the response of biochemical substances to nutrition limitation, and the food chain transmission and feedback of nutrition limitation. Meanwhile, we also put forward some perspectives for future research of ecological stoichiometry of plankton in China' s seas.

  6. Advanced research on separating prostate cancer stem cells

    International Nuclear Information System (INIS)

    Hao Yumei; He Xin; Song Naling

    2013-01-01

    Prostate cancer is a common malignant tumor in male urinary system,and may easily develop into the hormone refractory prostate cancer which can hardly be cured. Recent studies had found that the prostate cancer stem cells may be the source of the prostate cancer's occurrence,development, metastasis and recurrence. The therapy targeting the prostate cancer stem cells may be the effective way to cure prostate cancer. But these cells is too low to be detected. The difficulty lies in the low separation efficiency of prostate cancer stem cell, so the effectively separating prostate cancer stem cells occupied the main position for the more in-depth research of prostate cancer stem cells. This paper reviews the research progress and existing problems on the several main separating methods of prostate cancer stem cells, includes the fluorescence activated cells sorting and magnetic activated cells sorting based on prostate cancer stem cell surface markers, the side-population sorting and serum-free medium sphere forming sorting based on prostate cancer stem cell's biology. (authors)

  7. Research on advancement of technique for assessing ground seismic intensity

    International Nuclear Information System (INIS)

    Tamura, Keiichi; Kaneko, Masahiro; Honda, Riki; Tabuchi, Yoshihiro

    1997-01-01

    In the aseismatic design of nuclear power stations, as the characteristics of earthquake motion inputted in released base surface, the maximum amplitude and the frequency characteristics of earthquake motion, the presumption of earthquake motion using fault model, the time of continuation and the change of amplitude envelope with time are to be examined. In this research, in order to upgrade the earthquake motion used for aseismatic design, the method of evaluating quantitatively the amplifying characteristics of earthquake motion in unfair ground and the technique of setting design earthquake motion that can consider the change of structural state were investigated. The course of the research carried out so far is outlined. As to the amplifying characteristics of earthquake motion in unfair ground, the technique of analysis, the index showing the degree of amplifying of earthquake motion, the index showing the degree of unfairness of ground, the amplifying characteristics of earthquake motion in tray type base, and the evaluation of frequency zone of large degree of amplifying are reported. As to the design earthquake motion taking the plasticizing of structures in consideration, the analysis condition, the equivalent peculiar frequency and the equivalent damping constant and the design earthquake motion taking the plasticizing of structures in consideration are reported. (K.I.)

  8. Advances in Mushroom Research in the Last Decade

    Directory of Open Access Journals (Sweden)

    Huijuan Pan

    2006-01-01

    Full Text Available There has been a lot of progress in mushroom science and biotechnology in the last decade. The optimization of PFGE separation of fungal chromosomes allowed the study of the molecular karyotype of mushrooms and the assignment of genes to chromosomes. There are 115 genes encoded from different species of mushrooms. Cross breeding continues to be the principal method, but it is accompanied by the analyses of RAPD or RFLPs methods. The genetic makers are used and introduced into commercial large hybrids via introgression breeding. The complex traits such as yield, resistance to disease and quality characteristics, and quantitative traits more than one quantitative trait locus (QTL are found and used in practice. The transformants or transgenic mutant strains were obtained by Agrobacterium system or particle bombardment. At least 651 species representing 182 genera of hetero- and homobasidiomycetes mushrooms were researched containing antitumor or immunostimulating polysaccharides. Ergosterol in the lipid fraction was identified as one of the most active constituents. New sesquiterpenoid hydroquinones, steroids, oxalic acid, triterpenes, water-soluble lignins, sulfated polysaccharides, protein-bound polysaccharides are researched intensively as antimicrobial or antiviral agents. Many small molecular mass compounds exhibit cytotoxic activities, such as illudins, leaianafulvene, triterpenes (ganoderic acids, acetoxyscirpenediol, ergosterol peroxide, sterols. There are many other compounds or activities found in the mushrooms, such as antioxidative, hypoglycemic action, anti-inflammatory effect, hepatoprotective compounds, psychoactive compounds and activities.

  9. Parallel computing in genomic research: advances and applications

    Directory of Open Access Journals (Sweden)

    Ocaña K

    2015-11-01

    Full Text Available Kary Ocaña,1 Daniel de Oliveira2 1National Laboratory of Scientific Computing, Petrópolis, Rio de Janeiro, 2Institute of Computing, Fluminense Federal University, Niterói, Brazil Abstract: Today's genomic experiments have to process the so-called "biological big data" that is now reaching the size of Terabytes and Petabytes. To process this huge amount of data, scientists may require weeks or months if they use their own workstations. Parallelism techniques and high-performance computing (HPC environments can be applied for reducing the total processing time and to ease the management, treatment, and analyses of this data. However, running bioinformatics experiments in HPC environments such as clouds, grids, clusters, and graphics processing unit requires the expertise from scientists to integrate computational, biological, and mathematical techniques and technologies. Several solutions have already been proposed to allow scientists for processing their genomic experiments using HPC capabilities and parallelism techniques. This article brings a systematic review of literature that surveys the most recently published research involving genomics and parallel computing. Our objective is to gather the main characteristics, benefits, and challenges that can be considered by scientists when running their genomic experiments to benefit from parallelism techniques and HPC capabilities. Keywords: high-performance computing, genomic research, cloud computing, grid computing, cluster computing, parallel computing

  10. Advances in drug metabolism and pharmacogenetics research in Australia.

    Science.gov (United States)

    Mackenzie, Peter I; Somogyi, Andrew A; Miners, John O

    2017-02-01

    Metabolism facilitates the elimination, detoxification and excretion in urine or bile (as biotransformation products) of a myriad of structurally diverse drugs and other chemicals. The metabolism of drugs, non-drug xenobiotics and many endogenous compounds is catalyzed by families of drug metabolizing enzymes (DMEs). These include the hemoprotein-containing cytochromes P450, which function predominantly as monooxygenases, and conjugation enzymes that transfer a sugar, sulfate, acetate or glutathione moiety to substrates containing a suitable acceptor functional group. Drug and chemical metabolism, especially the enzymes that catalyse these reactions, has been the research focus of several groups in Australia for over four decades. In this review, we highlight the role of recent and current drug metabolism research in Australia, including elucidation of the structure and function of enzymes from the various DME families, factors that modulate enzyme activity in humans (e.g. drug-drug interactions, gene expression and genetic polymorphism) and the application of in vitro approaches for the prediction of drug metabolism parameters in humans, along with the broader pharmacological/clinical pharmacological and toxicological significance of drug metabolism and DMEs and their relevance to drug discovery and development, and to clinical practice. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Research advances in animal models of nonalcoholic fatty liver disease

    Directory of Open Access Journals (Sweden)

    HUANG Haiyan

    2014-09-01

    Full Text Available In recent years, the incidence of nonalcoholic fatty liver disease (NAFLD has increased gradually along with the rising prevalence of obesity, type 2 diabetes, and hyperlipidemia, and NAFLD has become one of the most common chronic liver diseases in the world and the second major liver disease after chronic viral hepatitis in China. However, its pathogenesis has not yet been clarified. Animal models are playing an important role in researches on NAFLD due to the facts that the development and progression of NAFLD require a long period of time, and ethical limitations exist in conducting drug trials in patients or collecting liver tissues from patients. The animal models with histopathology similar to that of NAFLD patients are reviewed, and their modeling principle, as well as the advantages and disadvantages, are compared. Animal models provide a powerful tool for further studies of NAFLD pathogenesis and drug screening for prevention and treatment of NAFLD.

  12. Advances in canine distemper virus pathogenesis research: a wildlife perspective.

    Science.gov (United States)

    Loots, Angelika K; Mitchell, Emily; Dalton, Desiré L; Kotzé, Antoinette; Venter, Estelle H

    2017-03-01

    Canine distemper virus (CDV) has emerged as a significant disease of wildlife, which is highly contagious and readily transmitted between susceptible hosts. Initially described as an infectious disease of domestic dogs, it is now recognized as a global multi-host pathogen, infecting and causing mass mortalities in a wide range of carnivore species. The last decade has seen the effect of numerous CDV outbreaks in various wildlife populations. Prevention of CDV requires a clear understanding of the potential hosts in danger of infection as well as the dynamic pathways CDV uses to gain entry to its host cells and its ability to initiate viral shedding and disease transmission. We review recent research conducted on CDV infections in wildlife, including the latest findings on the causes of host specificity and cellular receptors involved in distemper pathogenesis.

  13. [Research advances of fluid bio-mechanics in bone].

    Science.gov (United States)

    Chen, Zebin; Huo, Bo

    2017-04-01

    It has been found for more than one century that when experiencing mechanical loading, the structure of bone will adapt to the changing mechanical environment, which is called bone remodeling. Bone remodeling is charaterized as two processes of bone formation and bone resorption. A large number of studies have confirmed that the shear stress is resulted from interstitial fluid flow within bone cavities under mechanical loading and it is the key factor of stimulating the biological responses of bone cells. This review summarizes the major research progress during the past years, including the biological response of bone cells under fluid flow, the pressure within bone cavities, the theoretical modeling, numerical simulation and experiments about fluid flow within bone, and finally analyzes and predicts the possible tendency in this field in the future.

  14. Advancements of two dimensional correlation spectroscopy in protein researches

    Science.gov (United States)

    Tao, Yanchun; Wu, Yuqing; Zhang, Liping

    2018-05-01

    The developments of two-dimensional correlation spectroscopy (2DCOS) applications in protein studies are discussed, especially for the past two decades. The powerful utilities of 2DCOS combined with various analytical techniques in protein studies are summarized. The emphasis is on the vibration spectroscopic techniques including IR, NIR, Raman and optical activity (ROA), as well as vibration circular dichroism (VCD) and fluorescence spectroscopy. In addition, some new developments, such as hetero-spectral 2DCOS, moving-window correlation, and model based correlation, are also reviewed for their utility in the investigation of the secondary structure, denaturation, folding and unfolding changes of protein. Finally, the new possibility and challenges of 2DCOS in protein research are highlighted as well.

  15. Research advances in traditional Chinese medicine syndromes in cancer patients.

    Science.gov (United States)

    Ji, Qing; Luo, Yun-quan; Wang, Wen-hai; Liu, Xuan; Li, Qi; Su, Shi-bing

    2016-01-01

    Traditional Chinese medicine (TCM) syndrome, also known as TCM ZHENG or TCM pattern, is an integral and essential part of TCM theory that helps to guide the design of individualized treatments. A TCM syndrome, in essence, is a characteristic profile of all clinical manifestations in one patient that can be readily identified by a TCM practitioner. In this article, the authors reviewed the presentations of TCM syndromes in seven common malignancies (liver, lung, gastric, breast, colorectal, pancreatic and esophageal cancers), the objectivity and the standardization of TCM syndrome differentiation, the evaluation of TCM syndrome modeling in cancer research, and syndrome differentiation-guided TCM treatment of cancers. A better understanding of TCM syndrome theory, as well as its potential biological basis, may contribute greatly to the clinical TCM diagnosis and the treatment of cancer.

  16. Research on advanced system safety assessment procedures (4)

    International Nuclear Information System (INIS)

    Suzuki, Kazuhiko; Shimada, Yukiyasu

    2001-03-01

    The past research reports in the area of safety engineering proposed the Computer-aided HAZOP system to be applied to Nuclear Reprocessing Facilities. Automated HAZOP system has great advantage compared with human analysts in terms of accuracy of the results, and time required to conduct HAZOP studies. This report surveys the literature on risk assessment and safety design based on the concept of independent protection layers (IPLs). Furthermore, to improve HAZOP System, tool is proposed to construct the basic model and the internal state model. Such HAZOP system is applied to analyze two kinds of processes, where the ability of the proposed system is verified. In addition, risk assessment support system is proposed to integrate safety design environment and assessment result to be used by other plants as well as to enable the underline plant to use other plants' information. This technique can be implemented using web-based safety information systems. (author)

  17. Nanotechnology in stem cells research: advances and applications.

    Science.gov (United States)

    Deb, Kaushik Dilip; Griffith, May; Muinck, Ebo De; Rafat, Mehrdad

    2012-01-01

    Human beings suffer from a myriad of disorders caused by biochemical or biophysical alteration of physiological systems leading to organ failure. For a number of these conditions, stem cells and their enormous reparative potential may be the last hope for restoring function to these failing organ or tissue systems. To harness the potential of stem cells for biotherapeutic applications, we need to work at the size scale of molecules and processes that govern stem cells fate. Nanotechnology provides us with such capacity. Therefore, effective amalgamation of nanotechnology and stem cells - medical nanoscience or nanomedicine - offers immense benefits to the human race. The aim of this paper is to discuss the role and importance of nanotechnology in stem cell research by focusing on several important areas such as stem cell visualization and imaging, genetic modifications and reprogramming by gene delivery systems, creating stem cell niche, and similar therapeutic applications.

  18. NATO Advanced Research Workshop on Fundamental and Applied Electromagnetics

    CERN Document Server

    Maksimenko, Sergey

    2016-01-01

    This book presents the most relevant and recent results in the study of “Nanoelectromagnetics”, a recently born fascinating research discipline, whose popularity is fast arising with the intensive penetration of nanotechnology in the world of electronics applications. Studying nanoelectromagnetics means describing the interaction between electromagnetic radiation and quantum mechanical low-dimensional systems: this requires a full interdisciplinary approach, the reason why this book hosts contributions from the fields of fundamental and applied electromagnetics, of chemistry and technology of nanostructures and nanocomposites, of physics of nano-structures systems, etc. The book is aimed at providing the reader with the state of the art in Nanoelectromagnetics, from theoretical modelling to experimental characterization, from design to synthesis, from DC to microwave and terahertz applications, from the study of fundamental material properties to the analysis of complex systems and devices, from commercia...

  19. Solid state physics advances in research and applications

    CERN Document Server

    Turnbull, David

    1991-01-01

    The explosion of the science of mesoscopic structures is having a great impact on physics and electrical engineering because of the possible applications of these structures in microelectronic and optoelectronic devices of the future. This volume of Solid State Physics consists of two comprehensive and authoritative articles that discuss most of the physical problems that have so far been identified as being of importance in semiconductor nanostructures. Much of the volume is tutorial in characture--while at the same time time presenting current and vital theoretical and experimental results and a copious reference list--so it will be essential reading to all those taking a part in the research and development of this emerging technology.

  20. Recent advances in addictive disorders. Prevention. Current research and trends.

    Science.gov (United States)

    Kumpfer, K L; Hopkins, R

    1993-03-01

    The AOD prevention programs of the 1990s should be resiliency-focused and include interventions of sufficient dosage and strength. Although some child behavioral technology exists to tackle successfully changes in resiliency, additional prevention strategies need to be developed and studied. In some way, the prevention field is hampered by the lack of sufficient research in the child and adolescent psychiatry and psychology fields, that includes transactional research in parenting and child rearing for high-risk youth. We simply do not know enough to determine how parents and other adults can best foster resilience in children. Questions that arise include how much to protect children from environmental stressors and how much to push them to confront new life stressors in the form of challenges to develop new skills or talents. There are no simple answers to these questions, but a number of useful guidelines could help parents and teachers to increase resilience in youth. Some of the guidelines currently being stressed include developing in youth an increased sense of responsibility for their own success, helping them to identify their talents, motivating them to dedicate their lives to helping society rather than feeling their only purpose in life is to be consumers, providing realistic appraisals and feedback for youth rather than graciously building up their self-esteem, stressing multicultural competence in an ever-shrinking world, encouraging and valuing education and skills training, increasing cooperative solutions to problems rather than competitive or aggressive solutions, and increasing a sense of responsibility for others and caring for others. Clearly, these are important objectives for creating the type of citizens that can make American strong in the twentieth century.

  1. Basic research and industrialization of CANDU advanced fuel - A research for the improvement of RFSP code

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chang Hyo; Jang, Chang Sun; Han, Tae Young [Seoul National University, Seoul (Korea)

    2000-03-01

    The objective of this project is to improve the RFSP code by adopting three dimensional two neutron energy group model and accelerated iterative solution scheme (FDM3D) to 2 group diffusion equations as well. The major contents of this research are the derivation of the finite difference equation to three dimensional two neutron energy group diffusion equation, application of accelerated iterative solution scheme to the finite difference diffusion equation and validation of the improved RFSP code (FDM3D) through benchmark tests. We have shown that SOR/Chebyshev two parameter method and BICG-STAB/Wielandt method are more effective than that of RFSP in terms of computing speed. SOR/Chebyshev two parameter method shows better efficiency than BICG-STAB/Wielandt method. Because calculation efficiency of the latter depends on the right choice of pre-conditioner, however, it is considered that more studies are necessary to improve the efficiency of this latter method and to validate it. We have incorporated the new efficient method into the existing RFSP so that the resulting RFSP becomes much faster and more accurate. RFSP currently uses POWDERPUFS code as main lattice code, which is adequate to the neutron energy group model of RFSP. Because of this, we can not make the full advantage of advanced RFSP without adopting lattice code WIMS-AECL which can generate exact two neutron energy group constants. Therefore, we suggest developing a new CANDU design and analysis code which incorporate WIMS-AECL into FDM3D. 16 refs., 10 figs., 23 tabs. (Author)

  2. Translating advances in reading comprehension research to educational practice

    Directory of Open Access Journals (Sweden)

    Danielle S. McNamara

    2011-07-01

    Full Text Available The authors review five major findings in reading comprehension and their implications for educational practice. First, research suggests that comprehension skills are separable from decoding processes and important at early ages, suggesting that comprehension skills should be targeted early, even before the child learns to read. Second, there is an important distinction between reading processes and products, as well as their causal relationship: processes lead to certain products. Hence, instructional approaches and strategies focusing on processes are needed to improve students’ reading performance (i.e., product. Third, inferences are a crucial component of skilled comprehension. Hence, children need scaffolding and remediation to learn to generate inferences, even when they know little about the text topic. Fourth, comprehension depends on a complex interaction between the reader, the characteristics of the text, and the instructional task, highlighting the need for careful selection of instructional materials for individual students and specific groups of students. Finally, educators may benefit from heightened awareness of the limitations and inadequacies of standardized reading comprehension assessments, as well as the multidimensionality of comprehension to better understand their students’ particular strengths and weaknesses.

  3. Translating advances in reading comprehension research to educational practice

    Directory of Open Access Journals (Sweden)

    Danielle S. McNAMARA

    2011-11-01

    Full Text Available The authors review five major findings in reading comprehension and their implications for educational practice. First, research suggests that comprehension skills are separable from decodingprocesses and important at early ages, suggesting that comprehension skills should be targeted early, even before the child learns to read. Second, there is an important distinction between readingprocesses and products, as well as their causal relationship: processes lead to certain products. Hence, instructional approaches and strategies focusing on processes are needed to improve students’reading performance (i.e., product. Third, inferences are a crucial component of skilled comprehension. Hence, children need scaffolding and remediation to learn to generate inferences, even when they know little about the text topic. Fourth, comprehension depends on a complex interaction between the reader, the characteristics of the text, and the instructional task, highlighting the need for careful selection of instructional materials for individual students and specific groups of students. Finally, educators may benefit from heightened awareness of the limitations and inadequacies of standardized reading comprehension assessments, as well as the multidimensionality of comprehension to better understand their students’ particular strengths and weaknesses.

  4. Gender integration in coeducational classrooms: Advancing educational research and practice.

    Science.gov (United States)

    Fabes, Richard A; Martin, Carol Lynn; Hanish, Laura D; DeLay, Dawn

    2018-06-01

    Despite the fact that most boys and girls are in classrooms together, there is considerable variation in the degree to which their classrooms reflect gender integration (GI). In some classrooms, boys' and girls' relationships with each other are generally positive and harmonious. However, in other classes, students tend to only work with classmates of the same gender (i.e., gender segregation, GS), and cross-gender interactions seldom occur or, when they do, they may not be positive. As such, the coeducational context of schools provides no assurance that boys and girls work effectively together to learn, solve academic problems, and support one another in their academic efforts. The purpose of this perspective paper is to call attention to the importance of studying and understanding the role of GI in contemporary U.S. coeducational classrooms. Some of the costs associated with the failure to consider GI also are identified, as are implications for future research and educational practice. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  5. Parallel computing in genomic research: advances and applications.

    Science.gov (United States)

    Ocaña, Kary; de Oliveira, Daniel

    2015-01-01

    Today's genomic experiments have to process the so-called "biological big data" that is now reaching the size of Terabytes and Petabytes. To process this huge amount of data, scientists may require weeks or months if they use their own workstations. Parallelism techniques and high-performance computing (HPC) environments can be applied for reducing the total processing time and to ease the management, treatment, and analyses of this data. However, running bioinformatics experiments in HPC environments such as clouds, grids, clusters, and graphics processing unit requires the expertise from scientists to integrate computational, biological, and mathematical techniques and technologies. Several solutions have already been proposed to allow scientists for processing their genomic experiments using HPC capabilities and parallelism techniques. This article brings a systematic review of literature that surveys the most recently published research involving genomics and parallel computing. Our objective is to gather the main characteristics, benefits, and challenges that can be considered by scientists when running their genomic experiments to benefit from parallelism techniques and HPC capabilities.

  6. Assessment report of research and development activities FY2014. Activity: 'Advanced science research' (Final report)

    International Nuclear Information System (INIS)

    2015-09-01

    Japan Atomic Energy Agency (hereinafter referred to as 'JAEA') consulted an assessment committee, 'Evaluation Committee of Research Activities for Advanced Science Research' (hereinafter referred to as 'Committee') for final evaluation and prior assessment of 'Advanced Science Research,' in accordance with 'General Guideline for the Evaluation of Government Research and Development (R and D) Activities' by Cabinet Office, Government of Japan, 'Guideline for Evaluation of R and D in Ministry of Education, Culture, Sports, Science and Technology' and 'Regulation on Conduct for Evaluation of R and D Activities' by JAEA. In response to the JAEA's request, the Committee assessed the research programs and activities of the Advanced Science Research Center (hereinafter referred to as 'ASRC') for the period of five years from April 2010 and the research programs from April 2015. The Committee evaluated the management and the research programs of the ASRC based on the explanatory documents prepared by the ASRC and the oral presentations with questions-and-answers by the Director and the research group leaders. This report summarizes the results of the assessment by the Committee with the Committee report attached. (author)

  7. Research and Development Progress of National Key Laboratory of Advanced Composites on Advanced Aeronautical Resin Matrix Composites

    Directory of Open Access Journals (Sweden)

    LI Bintai

    2016-06-01

    Full Text Available Applications and research progress in advanced aeronautical resin matrix composites by National Key Laboratory of Advanced Composites (LAC were summarized. A novel interlaminar toughening technology employing ultra-thin TP non-woven fabric was developed in LAC, which significantly improved the compression after impact (CAI performances of composite laminates.Newly designed multilayer sandwich stealth composite structures exhibited a good broadband radar absorbing properties at 1-18 GHz.There were remarkable developments in high toughness and high temperature resin matrix composites, covering major composite processing technologies such as prepreg-autoclave procedure, liquid composite molding and automation manufacture, etc. Finally, numerical simulation and optimization methods were deliberately utilized in the study of composites curing behavior, resin flow and curing deformation. A composite material database was also established.In conclusion, LAC has been a great support for the development of aeronautical equipment, playing such roles as innovation leading, system dominating, foundation supporting and application ensuring of aerocomposites.

  8. Research on advanced system safety assessment procedures (II)

    International Nuclear Information System (INIS)

    Suzuki, Kazuhiko; Shimada, Yukiyasu

    1999-03-01

    HAZOP (Hazard and operability study) is a systematic technique, which requires the involvement of an experienced, interdisciplinary team of engineers, to identify hazards or operability problems throughout an entire facility by brainstorming. Though HAZOP is recognized as the useful safety assessment method, it requires a labor-intensive and time-consuming process. So recently computer-aided HAZOP has been proposed. The research report in 1998 (PNC PJ1612 98-001) presented prototype system, which carries out HAZOP and FT synthesis, by making use of proposed method. Relationships between states of input and output variables, internal and external events of each component are represented using decision tables, and the system is implemented by C++. In this study, the causalities of plant component malfunctions are described as component malfunction basic model and are stored in the computer. Thus, we have developed safety evaluation support system by considering the fault propagation path. Component malfunction basic model is made based on the information on the causalities between the abnormal state and each malfunction in components. This component malfunction basic model provides the common frame to describe abnormal situation in components. By using this basic model, not only state malfunction of component but also the consequence to external circumstance is assessed. G2, which is an excellent object-oriented developer tool in GUI (Graphical User Interface), is used as a tool for developing the system. By using the graphical editor in the system, the user can carry out HAZOP easily. We have applied this system to the Nuclear Reprocessing Facilities to demonstrate the utilities of developing system. (author)

  9. Advancements in flow-induced vibration research and design criteria

    International Nuclear Information System (INIS)

    Pettigrew, M.J.

    2009-01-01

    Two-phase flow exists in many nuclear components and, in particular, steam generators. So far relatively little research work has been done on two-phase flow-induced vibration probably because it is difficult to do. Two-phase flows are not homogeneous and are governed by an additional parameter called void fraction. This can lead to different flow patterns or regimes that can change completely the vibration behaviour. Fluidelastic instability, random turbulence excitation and detailed flow characteristics are being investigated in tube bundles subjected to two-phase cross flow. Fluidelastic instability of a tube bundle preferentially flexible in the flow direction was observed probably for the first time. This is particularly relevant to the problem of in-plane vibration of nuclear steam generator U-tubes and has resulted in changes in our design criteria. Unexpected quasi-periodic excitation forces were also measured in the tube bundle. These are attributed to an alternating wake in the lift direction and to fluctuating momentum flux in the drag direction. Vibration damping due to two-phase flow is very dependent on void fraction and appears directly related to the interface surface area between phases. Maximum damping values correspond to the transitions between flow regimes. Fibre optic probes were developed to measure the characteristics of two-phase flows. These probes are used to take detailed measurements in a triangular array of tubes in cross flow. The results show that the flow tends to stream between the tubes. These studies have yielded interesting results but have raised more questions that could lead to improved design criteria. The more puzzling results will be discussed in this presentation. Some of the dynamic phenomena will be illustrated by animation. (author)

  10. Research, development, demonstration, and early deployment policies for advanced-coal technology in China

    International Nuclear Information System (INIS)

    Zhao Lifeng; Gallagher, Kelly Sims

    2007-01-01

    Advanced-coal technologies will increasingly play a significant role in addressing China's multiple energy challenges. This paper introduces the current status of energy in China, evaluates the research, development, and demonstration policies for advanced-coal technologies during the Tenth Five-Year Plan, and gives policy prospects for advanced-coal technologies in the Eleventh Five-Year Plan. Early deployment policies for advanced-coal technologies are discussed and some recommendations are put forward. China has made great progress in the development of advanced-coal technologies. In terms of research, development, and demonstration of advanced-coal technologies, China has achieved breakthroughs in developing and demonstrating advanced-coal gasification, direct and indirect coal liquefaction, and key technologies of Integrated Gasification Combined Cycle (IGCC) and co-production systems. Progress on actual deployment of advanced-coal technologies has been more limited, in part due to insufficient supporting policies. Recently, industry chose Ultra Super Critical (USC) Pulverized Coal (PC) and Super Critical (SC) PC for new capacity coupled with pollution-control technology, and 300 MW Circulating Fluidized Bed (CFB) as a supplement

  11. Korea Superconducting tokamak advanced research project - Development of heating system

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Byung Ho [Korea Atomic Energy Research Institute, Taejon (Korea)

    1998-10-01

    The heating and current drive systems for KSTAR based on multiple technologies (neutral beam, ion cyclotron, lower hybrid and electron cyclotron) have been designed to provide heating and current drive capabilities as well as flexibility in the control of current density and pressure profiles needed to meet the mission and research objectives of the machine. They are designed to operate for long-pulse lengths of up to 300 s. The NBI system initially delivers 8 MW of neutral beam power to the plasma from one co-directed beam line and shall be upgraded to provide 20 MW of neutral beam power with two co-directed beam lines plus one counter-directed beam line. It will be capable of being reconfigured such that the source arrangement is changed from horizontal to vertical stacking, with 6 MW beam power to the plasmas per beam line, in order to facilitate profile control. The RF system initially delivers 6 MW of rf power to the plasma, using a single four-strap antenna mounted in a midplane port. The system will be upgraded to proved 12 MW of rf power through 2 adjacent ports. In the first phase, we completed the basic design of RF system and the system have the capabilities to be operationable for pulse length up to 300 sec and in the 25-60 MHz frequency range. Lower hybrid system initially provides 1.5 MW LH rf power to the plasma at 3.7 GHz through a horizontal port, which has a capability to be operated for pulse length up to 300 sec, and shall be upgraded to provide 4.5 MW of LH rf power to the plasma. In the first phase, we completed the basic design of LHCD system which incorporate the TPX-type launcher and independently phase-changeable transmission system for the fully phased coupler. The ECH system will deliver up to 0.5 MW of power to the plasma for up to 0.5 sec. In the first phase, we completed the basic design of ECH system which includes an 84 GHz gyrotron system, a transmission system, and a launcher. The basic design of the low loss transmission system

  12. Louisiana: a model for advancing regional e-Research through cyberinfrastructure.

    Science.gov (United States)

    Katz, Daniel S; Allen, Gabrielle; Cortez, Ricardo; Cruz-Neira, Carolina; Gottumukkala, Raju; Greenwood, Zeno D; Guice, Les; Jha, Shantenu; Kolluru, Ramesh; Kosar, Tevfik; Leger, Lonnie; Liu, Honggao; McMahon, Charlie; Nabrzyski, Jarek; Rodriguez-Milla, Bety; Seidel, Ed; Speyrer, Greg; Stubblefield, Michael; Voss, Brian; Whittenburg, Scott

    2009-06-28

    Louisiana researchers and universities are leading a concentrated, collaborative effort to advance statewide e-Research through a new cyberinfrastructure: computing systems, data storage systems, advanced instruments and data repositories, visualization environments and people, all linked together by software programs and high-performance networks. This effort has led to a set of interlinked projects that have started making a significant difference in the state, and has created an environment that encourages increased collaboration, leading to new e-Research. This paper describes the overall effort, the new projects and environment and the results to date.

  13. NASA University Research Centers Technical Advances in Education, Aeronautics, Space, Autonomy, Earth and Environment

    Science.gov (United States)

    Jamshidi, M. (Editor); Lumia, R. (Editor); Tunstel, E., Jr. (Editor); White, B. (Editor); Malone, J. (Editor); Sakimoto, P. (Editor)

    1997-01-01

    This first volume of the Autonomous Control Engineering (ACE) Center Press Series on NASA University Research Center's (URC's) Advanced Technologies on Space Exploration and National Service constitute a report on the research papers and presentations delivered by NASA Installations and industry and Report of the NASA's fourteen URC's held at the First National Conference in Albuquerque, New Mexico from February 16-19, 1997.

  14. Prejudice and Racism, Year 2008--Still Going Strong: Research on Reducing Prejudice with Recommended Methodological Advances

    Science.gov (United States)

    Utsey, Shawn O.; Ponterotto, Joseph G.; Porter, Jerlym S.

    2008-01-01

    This article addresses the origins, mechanisms, and expressions of prejudice. A selective review of research finds strong support for the validity of G. W. Allport's (1954) contact hypothesis conditions in reducing prejudice. Methodological advances in the study of prejudice are reviewed, and implications of research findings for counselors are…

  15. How novice, skilled and advanced clinical researchers include variables in a case report form for clinical research: a qualitative study.

    Science.gov (United States)

    Chu, Hongling; Zeng, Lin; Fetters, Micheal D; Li, Nan; Tao, Liyuan; Shi, Yanyan; Zhang, Hua; Wang, Xiaoxiao; Li, Fengwei; Zhao, Yiming

    2017-09-18

    Despite varying degrees in research training, most academic clinicians are expected to conduct clinical research. The objective of this research was to understand how clinical researchers of different skill levels include variables in a case report form for their clinical research. The setting for this research was a major academic institution in Beijing, China. The target population was clinical researchers with three levels of experience, namely, limited clinical research experience, clinicians with rich clinical research experience and clinical research experts. Using a qualitative approach, we conducted 13 individual interviews (face to face) and one group interview (n=4) with clinical researchers from June to September 2016. Based on maximum variation sampling to identify researchers with three levels of research experience: eight clinicians with limited clinical research experience, five clinicians with rich clinical research experience and four clinical research experts. These 17 researchers had diverse hospital-based medical specialties and or specialisation in clinical research. Our analysis yields a typology of three processes developing a case report form that varies according to research experience level. Novice clinician researchers often have an incomplete protocol or none at all, and conduct data collection and publication based on a general framework. Experienced clinician researchers include variables in the case report form based on previous experience with attention to including domains or items at risk for omission and by eliminating unnecessary variables. Expert researchers consider comprehensively in advance data collection and implementation needs and plan accordingly. These results illustrate increasing levels of sophistication in research planning that increase sophistication in selection for variables in the case report form. These findings suggest that novice and intermediate-level researchers could benefit by emulating the comprehensive

  16. ADVANCED FUSION TECHNOLOGY RESEARCH AND DEVELOPMENT. ANNUAL REPORT TO THE US DEPARTMENT OF ENERGY

    International Nuclear Information System (INIS)

    PROJECT STAFF

    2001-01-01

    OAK A271 ADVANCED FUSION TECHNOLOGY RESEARCH AND DEVELOPMENT ANNUAL REPORT TO THE US DEPARTMENT OF ENERGY. The General Atomics (GA) Advanced Fusion Technology Program seeks to advance the knowledge base needed for next-generation fusion experiments, and ultimately for an economical and environmentally attractive fusion energy source. To achieve this objective, they carry out fusion systems design studies to evaluate the technologies needed for next-step experiments and power plants, and they conduct research to develop basic and applied knowledge about these technologies. GA's Advanced Fusion Technology program derives from, and draws on, the physics and engineering expertise built up by many years of experience in designing, building, and operating plasma physics experiments. The technology development activities take full advantage of the GA DIII-D program, the DIII-D facility and the Inertial Confinement Fusion (ICF) program and the ICF Target Fabrication facility

  17. FY2009 Annual Progress Report for Advanced Combustion Engine Research and Development

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2009-12-01

    Fiscal Year 2009 Annual Progress Report for the Advanced Combustion Engine Research and Development (R&D) subprogram. The Advanced Combustion Engine R&D subprogram supports the mission of the VTP program by removing the critical technical barriers to commercialization of advanced internal combustion engines (ICEs) for passenger and commercial vehicles that meet future Federal emissions regulations. Dramatically improving the efficiency of ICEs and enabling their introduction in conventional as well as hybrid electric vehicles is the most promising and cost-effective approach to increasing vehicle fuel economy over the next 30 years.

  18. Advanced Scientific Computing Research Exascale Requirements Review. An Office of Science review sponsored by Advanced Scientific Computing Research, September 27-29, 2016, Rockville, Maryland

    Energy Technology Data Exchange (ETDEWEB)

    Almgren, Ann [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); DeMar, Phil [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Vetter, Jeffrey [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Riley, Katherine [Argonne Leadership Computing Facility, Argonne, IL (United States); Antypas, Katie [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Bard, Deborah [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). National Energy Research Scientific Computing Center (NERSC); Coffey, Richard [Argonne National Lab. (ANL), Argonne, IL (United States); Dart, Eli [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Energy Science Network; Dosanjh, Sudip [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Gerber, Richard [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Hack, James [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Monga, Inder [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Energy Science Network; Papka, Michael E. [Argonne National Lab. (ANL), Argonne, IL (United States); Rotman, Lauren [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Energy Science Network; Straatsma, Tjerk [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Wells, Jack [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Bernholdt, David E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Bethel, Wes [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Bosilca, George [Univ. of Tennessee, Knoxville, TN (United States); Cappello, Frank [Argonne National Lab. (ANL), Argonne, IL (United States); Gamblin, Todd [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Habib, Salman [Argonne National Lab. (ANL), Argonne, IL (United States); Hill, Judy [Oak Ridge Leadership Computing Facility, Oak Ridge, TN (United States); Hollingsworth, Jeffrey K. [Univ. of Maryland, College Park, MD (United States); McInnes, Lois Curfman [Argonne National Lab. (ANL), Argonne, IL (United States); Mohror, Kathryn [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Moore, Shirley [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Moreland, Ken [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Roser, Rob [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Shende, Sameer [Univ. of Oregon, Eugene, OR (United States); Shipman, Galen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Williams, Samuel [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2017-06-20

    The widespread use of computing in the American economy would not be possible without a thoughtful, exploratory research and development (R&D) community pushing the performance edge of operating systems, computer languages, and software libraries. These are the tools and building blocks — the hammers, chisels, bricks, and mortar — of the smartphone, the cloud, and the computing services on which we rely. Engineers and scientists need ever-more specialized computing tools to discover new material properties for manufacturing, make energy generation safer and more efficient, and provide insight into the fundamentals of the universe, for example. The research division of the U.S. Department of Energy’s (DOE’s) Office of Advanced Scientific Computing and Research (ASCR Research) ensures that these tools and building blocks are being developed and honed to meet the extreme needs of modern science. See also http://exascaleage.org/ascr/ for additional information.

  19. Low-rank coal research: Volume 2, Advanced research and technology development: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Mann, M.D.; Swanson, M.L.; Benson, S.A.; Radonovich, L.; Steadman, E.N.; Sweeny, P.G.; McCollor, D.P.; Kleesattel, D.; Grow, D.; Falcone, S.K.

    1987-04-01

    Volume II contains articles on advanced combustion phenomena, combustion inorganic transformation; coal/char reactivity; liquefaction reactivity of low-rank coals, gasification ash and slag characterization, and fine particulate emissions. These articles have been entered individually into EDB and ERA. (LTN)

  20. Setting health research priorities using the CHNRI method: IV. Key conceptual advances

    Directory of Open Access Journals (Sweden)

    Igor Rudan

    2016-06-01

    Full Text Available Child Health and Nutrition Research Initiative (CHNRI started as an initiative of the Global Forum for Health Research in Geneva, Switzerland. Its aim was to develop a method that could assist priority setting in health research investments. The first version of the CHNRI method was published in 2007–2008. The aim of this paper was to summarize the history of the development of the CHNRI method and its key conceptual advances.

  1. Report of the review committee on evaluation of the research subjects in the field of advanced science research (FY2000)

    International Nuclear Information System (INIS)

    2000-10-01

    On the basis of the JAERI's Basic Guidelines for the Research Evaluation Methods and the Practices Manuals of the Institution Evaluation Committee, the Ad Hoc Review Committee composed of eight experts was set up under the Research Evaluation Committee of the JAERI in order to review the research themes completed in FY1999, those to be ended through FY2000, and those planned for five years starting in FY2001 in the Advanced Science Research Center. The Ad Hoc Review Committee meeting was held on July 17, 2000. According to the review methods including review items, points of review and review criteria, determined by the Research Evaluation Committee, the review was conducted based on the research result/plan documents submitted in advance and presentations by the Research Group Leaders. The review report was submitted to the Research Evaluation Committee for further review and discussions in its meeting held on August 31, 2000. The Research Evaluation Committee recognized the review results as appropriate. This report describes the review results. (author)

  2. NATO Advanced Research Institute on the Application of Systems Science to Energy Policy Planning

    CERN Document Server

    Cherniavsky, E; Laughton, M; Ruff, L

    1981-01-01

    The Advanced Research Institute (ARI) on "The Application of Systems Science to Energy Policy Planning" was held under the auspices of the NATO Special Programme Panel on Systems Science in collaboration with the National Center for Analysis of Energy Sys­ tems, Brookhaven National Laboratory, USA, as a part of the NATO Science Committee's continuous effort to promote the advancement of science through international cooperation. Advanced Research Institutes are sponsored by the NATO Science Committee for the purposes of bringing together senior scientists to seek consensus on an assessment of the present state of knowl­ edge on a specific topic and to make recommendations for future research directions. Meetings are structured to encourage inten­ sive group discussion. Invitees are carefully selected so that the group as a whole will contain the experience and expertise neces­ sary to make the conclusions valid and significant. A final report is published presenting the various viewpoints and conclusions....

  3. How institutional change and individual researchers helped advance clinical guidelines in American health care.

    Science.gov (United States)

    Nigam, Amit

    2013-06-01

    Clinical guidelines are important tools for managing health care quality. Research on the origins of guidelines primarily focuses on the institutional causes of their emergence and growth. Individual medical researchers, however, have played important roles. This paper develops knowledge of the role of individual medical researchers in advancing guidelines, and of how researchers' efforts were enabled or constrained by broader institutional changes. Drawing on an analytical case study focused on the role of Kerr White, John Wennberg, and Robert Brook, it shows that guidelines were a product of the interplay between institutional change in the medical field and actions by individual researchers, acting as institutional entrepreneurs. Increased government involvement in the health care field triggered the involvement of a range of new actors in health care. These new organizations created a context that allowed individual researchers to advance guidelines by creating job opportunities, providing research funding, and creating opportunities for researchers to engage with the policy process. Individual researchers availed of this context to both advance their ideas, and to draw new actors into the field. Copyright © 2013. Published by Elsevier Ltd.

  4. Analysis of Petroleum Technology Advances Through Applied Research by Independent Oil Producers

    Energy Technology Data Exchange (ETDEWEB)

    Brashear, Jerry P.; North, Walter B.; Thomas Charles P.; Becker, Alan B.; Faulder, David D.

    2000-01-12

    Petroleum Technology Advances Through Applied Research by Independent Oil Producers is a program of the National Oil Research Program, U.S. Department of Energy. Between 1995 and 1998, the program competitively selected and cost-shared twenty-two projects with small producers. The purpose was to involve small independent producers in testing technologies of interest to them that would advance (directly or indirectly) one or more of four national program objectives: (1) Extend the productive life of reservoirs; (2) Increase production and/or reserves; (3) Improve environmental performance; and (4) Broaden the exchange of technology information.

  5. Utilizing Advanced Psychometric Methods in Research on Trait Expression across Situations

    DEFF Research Database (Denmark)

    Lang, Jonas W. B.; Tackett, Jennifer; Zettler, Ingo

    2017-01-01

    Lievens emphasized the extent to which new measurement tools and additional statistics can be used to advance research on trait expression across situations. We suggest that advanced psychometric models represent additional important and complementary building blocks for progress and new insights...... in research on trait expression across situations. Here, we offer two specific examples of this: (1) Item Response Theory modelling of within-person variability simultaneous with estimation of latent trait levels and (2) estimation of latent trait and latent situation factors from a multitrait...

  6. Advance directives in dementia research: The opinions and arguments of clinical researchers − an empirical study

    NARCIS (Netherlands)

    K.R. Jongsma (Karin); S. van de Vathorst (Suzanne)

    2015-01-01

    textabstractIn order to discover an effective treatment for dementia it is necessary to include dementia patients in clinical research trials. Dementia patients face an increased risk to lose the capacity to consent to research participation, and research possibilities with incompetent participants

  7. The outline report of advanced basic engineering research in the fiscal year 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-08-01

    The JNC has initiated the cooperation with universities and research institutes for advanced basic engineering on 1995. The number of research cooperation theme is increasing and satisfactorily improving in the forth year, 1998. The objective of this program is to promote the advanced basic engineering research with universities and research institutes in relation with the JNC's projects. The facilities and equipment of the JNC are mainly provided to the cooperation. The JNC has settled the research cooperation themes. The universities and research institute have applied to the themes with their issues, working plans and personnel. The JNC has selected the issues and personnel, and put into practice the cooperation with accepting guest staffs and/or research fellows from the universities. This report summarizes the results of the advanced basic engineering research cooperation executed in the fiscal year, 1998. The total number of issues is 34 for the 29 themes; those are categorized in to two groups. The one is related to the fast breeder reactor technologies and the other is on the environmental technologies. The 12 issues are finished in the fiscal year, 1998, in which the 9 issues are for the fast breeder reactor technologies and the 3 issues are for the environmental technologies. The themes/the issues, the host group, host key persons, university side key persons, a form of cooperation are summarized in the tables. The summary reports of research activities by the all cooperators are presented under the particular format. Those describe the total schedule, a form of cooperation, the research objective, the outline of research contents, main facilities for using, research status, research results, future schedules and bibliographies relevant to the research cooperation. The 25 tables and 158 figures are included. (Y. Tanaka)

  8. The outline report of advanced basic engineering research in the fiscal year 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-08-01

    The JNC has initiated the cooperation with universities and research institutes for advanced basic engineering on 1995. The number of research cooperation theme is increasing and satisfactorily improving in the forth year, 1998. The objective of this program is to promote the advanced basic engineering research with universities and research institutes in relation with the JNC's projects. The facilities and equipment of the JNC are mainly provided to the cooperation. The JNC has settled the research cooperation themes. The universities and research institute have applied to the themes with their issues, working plans and personnel. The JNC has selected the issues and personnel, and put into practice the cooperation with accepting guest staffs and/or research fellows from the universities. This report summarizes the results of the advanced basic engineering research cooperation executed in the fiscal year, 1998. The total number of issues is 34 for the 29 themes; those are categorized in to two groups. The one is related to the fast breeder reactor technologies and the other is on the environmental technologies. The 12 issues are finished in the fiscal year, 1998, in which the 9 issues are for the fast breeder reactor technologies and the 3 issues are for the environmental technologies. The themes/the issues, the host group, host key persons, university side key persons, a form of cooperation are summarized in the tables. The summary reports of research activities by the all cooperators are presented under the particular format. Those describe the total schedule, a form of cooperation, the research objective, the outline of research contents, main facilities for using, research status, research results, future schedules and bibliographies relevant to the research cooperation. The 25 tables and 158 figures are included. (Y. Tanaka)

  9. Advancing vector biology research: a community survey for future directions, research applications and infrastructure requirements

    Science.gov (United States)

    Kohl, Alain; Pondeville, Emilie; Schnettler, Esther; Crisanti, Andrea; Supparo, Clelia; Christophides, George K.; Kersey, Paul J.; Maslen, Gareth L.; Takken, Willem; Koenraadt, Constantianus J. M.; Oliva, Clelia F.; Busquets, Núria; Abad, F. Xavier; Failloux, Anna-Bella; Levashina, Elena A.; Wilson, Anthony J.; Veronesi, Eva; Pichard, Maëlle; Arnaud Marsh, Sarah; Simard, Frédéric; Vernick, Kenneth D.

    2016-01-01

    Vector-borne pathogens impact public health, animal production, and animal welfare. Research on arthropod vectors such as mosquitoes, ticks, sandflies, and midges which transmit pathogens to humans and economically important animals is crucial for development of new control measures that target transmission by the vector. While insecticides are an important part of this arsenal, appearance of resistance mechanisms is increasingly common. Novel tools for genetic manipulation of vectors, use of Wolbachia endosymbiotic bacteria, and other biological control mechanisms to prevent pathogen transmission have led to promising new intervention strategies, adding to strong interest in vector biology and genetics as well as vector–pathogen interactions. Vector research is therefore at a crucial juncture, and strategic decisions on future research directions and research infrastructure investment should be informed by the research community. A survey initiated by the European Horizon 2020 INFRAVEC-2 consortium set out to canvass priorities in the vector biology research community and to determine key activities that are needed for researchers to efficiently study vectors, vector-pathogen interactions, as well as access the structures and services that allow such activities to be carried out. We summarize the most important findings of the survey which in particular reflect the priorities of researchers in European countries, and which will be of use to stakeholders that include researchers, government, and research organizations. PMID:27677378

  10. Current Research on Containment Technologies for Verification Activities: Advanced Tools for Maintaining Continuity of Knowledge

    International Nuclear Information System (INIS)

    Smartt, H.; Kuhn, M.; Krementz, D.

    2015-01-01

    The U.S. National Nuclear Security Administration (NNSA) Office of Non-proliferation and Verification Research and Development currently funds research on advanced containment technologies to support Continuity of Knowledge (CoK) objectives for verification regimes. One effort in this area is the Advanced Tools for Maintaining Continuity of Knowledge (ATCK) project. Recognizing that CoK assurances must withstand potential threats from sophisticated adversaries, and that containment options must therefore keep pace with technology advances, the NNSA research and development on advanced containment tools is an important investment. The two ATCK efforts underway at present address the technical containment requirements for securing access points (loop seals) and protecting defined volumes. Multiple U.S. national laboratories are supporting this project: Sandia National Laboratories (SNL), Savannah River National Laboratory (SRNL), and Oak Ridge National Laboratory (ORNL). SNL and SRNL are developing the ''Ceramic Seal,'' an active loop seal that integrates multiple advanced security capabilities and improved efficiency housed within a small-volume ceramic body. The development includes an associated handheld reader and interface software. Currently at the prototype stage, the Ceramic Seal will undergo a series of tests to determine operational readiness. It will be field tested in a representative verification trial in 2016. ORNL is developing the Whole Volume Containment Seal (WCS), a flexible conductive fabric capable of enclosing various sizes and shapes of monitored items. The WCS includes a distributed impedance measurement system for imaging the fabric surface area and passive tamper-indicating features such as permanent-staining conductive ink. With the expected technology advances from the Ceramic Seal and WCS, the ATCK project takes significant steps in advancing containment technologies to help maintain CoK for various verification

  11. Final report of the group research. Advanced Technology for Medical Imaging Research. 1996-2000 FY

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-03-01

    This report involves the organization of the research groups (4 units of radiopharmaceutical chemistry, radiotracer and radiopharmacology, clinical imaging, and molecular informative research), 5 research reports and 38 published research papers. The research reports concern Fundamental researches on the availability and production of PET radiopharmaceuticals using the National Institute of Radiological Sciences (NIRS) cyclotron, Design and evaluation of in vivo radiopharmaceuticals for PET measurement (kinetics and metabolism in small animals and primates), Fundamental studies on development of technique radiation measurement, Clinical application of medical imaging technology in the fields of neuroscience, cardiovascular, cancer diagnosis and others, and A study to establish and evaluate a lung cancer screening system using spiral CT units which is in pilot-progress in Kanto and Kansai regions. (N.I.)

  12. Innovation in Flight: Research of the NASA Langley Research Center on Revolutionary Advanced Concepts for Aeronautics

    Science.gov (United States)

    Chambers, Joseph R.

    2005-01-01

    The goal of this publication is to provide an overview of the topic of revolutionary research in aeronautics at Langley, including many examples of research efforts that offer significant potential benefits, but have not yet been applied. The discussion also includes an overview of how innovation and creativity is stimulated within the Center, and a perspective on the future of innovation. The documentation of this topic, especially the scope and experiences of the example research activities covered, is intended to provide background information for future researchers.

  13. Advanced Life Support Research and Technology Transfer at the University of Guelph

    Directory of Open Access Journals (Sweden)

    Dixon M.

    2017-02-01

    Full Text Available Research and technology developments surrounding Advanced Life-Support (ALS began at the University of Guelph in 1992 as the Space and Advanced Life Support Agriculture (SALSA program, which now represents Canada’s primary contribution to ALS research. The early focus was on recycling hydroponic nutrient solutions, atmospheric gas analysis and carbon balance, sensor research and development, inner/intra-canopy lighting and biological filtration of air in closed systems. With funding from federal, provincial and industry partners, a new generation of technology emerged to address the challenges of deploying biological systems as fundamental components of life-support infrastructure for long-duration human space exploration. Accompanying these advances were a wide range of technology transfer opportunities in the agri-food and health sectors, including air and water remediation, plant and environment sensors, disinfection technologies, recyclable growth substrates and advanced light emitting diode (LED lighting systems. This report traces the evolution of the SALSA program and catalogues the benefits of ALS research for terrestrial and non-terrestrial applications.

  14. Integrating Social Neuroscience and Social Work: Innovations for Advancing Practice-Based Research

    Science.gov (United States)

    Matto, Holly C.; Strolin-Goltzman, Jessica

    2010-01-01

    Throughout the social work profession, there is ongoing interest in building a social science agenda that can address the complex practice-based questions faced by social work professionals today. Methodological innovations and unique funding opportunities have already significantly advanced research on social work practice. Still, there is…

  15. Advancing Sexuality Studies: A Short Course on Sexuality Theory and Research Methodologies

    Science.gov (United States)

    Fletcher, Gillian; Dowsett, Gary W.; Duncan, Duane; Slavin, Sean; Corboz, Julienne

    2013-01-01

    Critical Sexuality Studies is an emerging field of academic enquiry linked to an international network of advocacy agencies, activists, and political issues. This paper reports on the development of an advanced short course in sexuality theory and research, drawing on Critical Sexuality Studies and aiming directly at academics in developing…

  16. Research Advances: Paper Batteries, Phototriggered Microcapsules, and Oil-Free Plastic Production

    Science.gov (United States)

    King, Angela G.

    2010-01-01

    Chemists continue to work at the forefront of materials science research. Recent advances include application of bioengineering to produce plastics from renewable biomass instead of petroleum, generation of paper-based batteries, and development of phototriggerable microcapsules for chemical delivery. In this article, the author provides summaries…

  17. Using the Student Research Project to Integrate Macroeconomics and Statistics in an Advanced Cost Accounting Course

    Science.gov (United States)

    Hassan, Mahamood M.; Schwartz, Bill N.

    2014-01-01

    This paper discusses a student research project that is part of an advanced cost accounting class. The project emphasizes active learning, integrates cost accounting with macroeconomics and statistics by "learning by doing" using real world data. Students analyze sales data for a publicly listed company by focusing on the company's…

  18. Lights, Camera, Action: Advancing Learning, Research, and Program Evaluation through Video Production in Educational Leadership Preparation

    Science.gov (United States)

    Friend, Jennifer; Militello, Matthew

    2015-01-01

    This article analyzes specific uses of digital video production in the field of educational leadership preparation, advancing a three-part framework that includes the use of video in (a) teaching and learning, (b) research methods, and (c) program evaluation and service to the profession. The first category within the framework examines videos…

  19. Research Strategies for Academic Medical Centers: A Framework for Advancements toward Translational Excellence

    Science.gov (United States)

    Haley, Rand; Champagne, Thomas J., Jr.

    2017-01-01

    This review article presents a simplified framework for thinking about research strategy priorities for academic medical centers (AMCs). The framework can serve as a precursor to future advancements in translational medicine and as a set of planning guideposts toward ultimate translational excellence. While market pressures, reform uncertainties,…

  20. The Advances in Research on the Pharmacological Effects of Fructus Ligustri Lucidi

    Directory of Open Access Journals (Sweden)

    Zunting Pang

    2015-01-01

    Full Text Available Fructus Ligustri Lucidi is a well-known invigorator in Chinese materia medica with hepatoprotective effect, anticancer activity, antioxidant activity, and so on. And oleanolic acids are the major pharmacologically active components in Fructus Ligustri Lucidi. So it has great value in medical health, and may be developed to a complementary and alternative medicine through further research. In this paper, the advances in research on pharmacological effects of Fructus Ligustri Lucidi were summarized by reviewing the recent related literature.

  1. Proceedings of JAEA-KPSI 8th symposium on advanced photon research

    International Nuclear Information System (INIS)

    2008-08-01

    JAEA-KPSI-APRC 8th Symposium on Advanced Photon Research was held at Kansai Photon Research Institute, Japan Atomic Energy Agency (JAEA-KPSI) in Kizu, Kyoto on June 4th - 5th, 2007. This report consists of contributed papers for the speeches and poster presentations in JAEA-KPSI-APRC 8th Symposium. The 33 of the presented papers are indexed individually. (J.P.N.)

  2. Restoration in Its Natural Context: How Ecological Momentary Assessment Can Advance Restoration Research

    Directory of Open Access Journals (Sweden)

    Femke Beute

    2016-04-01

    Full Text Available More and more people use self-tracking technologies to track their psychological states, physiology, and behaviors to gain a better understanding of themselves or to achieve a certain goal. Ecological Momentary Assessment (EMA also offers an excellent opportunity for restorative environments research, which examines how our physical environment (especially nature can positively influence health and wellbeing. It enables investigating restorative health effects in everyday life, providing not only high ecological validity but also opportunities to study in more detail the dynamic processes playing out over time on recovery, thereby bridging the gap between laboratory (i.e., short-term effects and epidemiological (long-term effects research. We have identified four main areas in which self-tracking could help advance restoration research: (1 capturing a rich set of environment types and restorative characteristics; (2 distinguishing intra-individual from inter-individual effects; (3 bridging the gap between laboratory and epidemiological research; and (4 advancing theoretical insights by measuring a more broad range of effects in everyday life. This paper briefly introduces restorative environments research, then reviews the state of the art of self-tracking technologies and methodologies, discusses how these can be implemented to advance restoration research, and presents some examples of pioneering work in this area.

  3. Recent advances in Ni-H2 technology at NASA Lewis Research Center

    Science.gov (United States)

    Gonzalezsanabria, O. D.; Britton, D. L.; Smithrick, J. J.; Reid, M. A.

    1986-01-01

    The NASA Lewis Research Center has concentrated its efforts on advancing the Ni-H2 system technology for low Earth orbit applications. Component technology as well as the design principles were studied in an effort to understand the system behavior and failure mechanisms in order to increase performance and extend cycle life. The design principles were previously addressed. The component development is discussed, in particular the separator and nickel electrode and how these efforts will advance the Ni-H2 system technology.

  4. Planning report for establishment of research infrastructure for national advanced radiation technology

    International Nuclear Information System (INIS)

    Kuk, Il Hyun; Byun, Myung Woo; Lee, Ju Woon

    2005-04-01

    Establishment of research infrastructure and assistant of industry renovation is needed to achieve technology level-up in the all industry areas including plant engineering, material engineering, polymers, nondestructive tests, radioisotope tracer application, environment engineering, medical science, agriculture, sterilization, sprouting, biotechnology and aerospace, which would be the core motivation of our future industry. Especially for early settlement of research environment for the new RT-specialized national institute, Advanced Radiation Technology Institute (ARTI) in Jeongup, Chonbuk, Korea is essential. For this purpose, an intensive system construction is demanded including: 1) Area of establishment of the system assisting radiation technology advancement: It is expected that radioisotope production for industrial or medical uses and activation of the related researches and training of experts by manufacture, installation, and operation of 30 MeV cyclotron. It also can be contributed in the promotion of national radiation related science and technology by establishment of a basic and advanced analysis system. 2) Area of establishment of training and education system of RT experts. 3) Area of establishment of a system for technological assistance for industry and industry-university-institute network. Contribution to balanced regional development and promotion of national RT-based science through establishment of RT industry cluster with Advanced Radiation Technology Institute (ARTi) at Jeongup as the center figure

  5. Conducting Biobehavioral Research in Patients With Advanced Cancer: Recruitment Challenges and Solutions.

    Science.gov (United States)

    Gilbertson-White, Stephanie; Bohr, Nicole; Wickersham, Karen E

    2017-10-01

    Despite significant advances in cancer treatment and symptom management interventions over the last decade, patients continue to struggle with cancer-related symptoms. Adequate baseline and longitudinal data are crucial for designing interventions to improve patient quality of life and reduce symptom burden; however, recruitment of patients with advanced cancer in longitudinal research is difficult. Our purpose is to describe challenges and solutions to recruitment of patients with advanced cancer in two biobehavioral research studies examining cancer-related symptoms. Study 1: Symptom data and peripheral blood for markers of inflammation were collected from newly diagnosed patients receiving chemotherapy on the first day of therapy and every 3-4 weeks for up to 6 months. Study 2: Symptom data, blood, and skin biopsies were collected from cancer patients taking epidermal growth factor receptor inhibitors at specific time points over 4 months. Screening and recruitment results for both studies are summarized. Timing informed consent with baseline data collection prior to treatment initiation was a significant recruitment challenge for both the studies. Possible solutions include tailoring recruitment to fit clinic needs, increasing research staff availability during clinic hours, and adding recruitment sites. Identifying solutions to these challenges will permit the conduct of studies that may lead to identification of factors contributing to variability in symptoms and development of tailored patient interventions for patients with advanced cancer.

  6. Redefining responsible research and innovation for the advancement of biobanking and biomedical research.

    Science.gov (United States)

    Yu, Helen

    2016-12-01

    One of the core objectives of responsible research and innovation (RRI) is to maximize the value of publicly funded research so that it may be returned to benefit society. However, while RRI encourages innovation through societal engagement, it can give rise to complex and previously untested issues that challenge the existing legal frameworks on intellectual property (IP) and public entitlement to benefits of research. In the case of biobanking, the personal nature of human biological materials and often altruistic intention of participants to donate samples intensifies the need to adhere to RRI principles with respect to the research, development, and commercialization of innovations derived from biobanks. However, stakeholders participate and collaborate with others in the innovation process to fulfill their own agenda. Without IP to safeguard investments in R&D, stakeholders may hesitate to contribute to the translation of discoveries into innovations. To realize the public benefit objective, RRI principles must protect the interests of stakeholders involved in the translation and commercialization of knowledge. This article explores the seemingly contradictory and competing objectives of open science and commercialization and proposes a holistic innovation framework directed at improving RRI practice for positive impact on obtaining the optimal social and economic values from research.

  7. The Budapest research reactor as an advanced research facility for the early 21st century

    International Nuclear Information System (INIS)

    Vidovszky, I.

    2001-01-01

    The Budapest Research Reactor, Hungary's first nuclear facility was originally put into operation in 1959. The reactor serves for: basic and applied research, technological and commercial applications, education and training. The main goal of the reactor is to serve neutron research. This unique research possibility is used by a broad user community of Europe. Eight instruments for neutron scattering, radiography and activation analyses are already used, others (e.g. time of flight spectrometer, neutron reflectometer) are being installed. The majority of these instruments will get a much improved utilization when the cold neutron source is put into operation. In 1999 the Budapest Research Reactor was operated for 3129 full power hours in 14 periods. The normal operation period took 234 hours (starting Monday noon and finishing Thursday morning). The entire production for the year 1999 was 1302 MW days. This is a slightly reduced value, due to the installation of the cold neutron source. For the year 2000 a somewhat longer operation is foreseen (near to 4000 hours), as the cold neutron source will be operational. The operation of the reactor is foreseen at least up to the end of the first decade of the 21 st century. (author)

  8. NATO Advanced Research Workshop on the Mechanisms of Reactions of Organometallic Compounds with Surfaces

    CERN Document Server

    Williams, J

    1989-01-01

    A NATO Advanced Research Workshop on the "Mechanisms of Reactions of Organometallic Compounds with Surfaces" was held in St. Andrews, Scotland in June 1988. Many of the leading international researchers in this area were present at the workshop and all made oral presentations of their results. In addition, significant amounts of time were set aside for Round Table discussions, in which smaller groups considered the current status of mechanistic knowledge, identified areas of dispute or disagreement, and proposed experiments that need to be carried out to resolve such disputes so as to advance our understanding of this important research area. All the papers presented at the workshop are collected in this volume, together with summaries of the conclusions reached at the Round Table discussions. The workshop could not have taken place without financial support from NATO, and donations were also received from Associated Octel, Ltd., STC Ltd., and Epichem Ltd., for which the organisers are very grateful. The orga...

  9. ESTIMATION OF SURVIVAL IN PATIENTS WITH ADVANCED OVARIAN CANCER – ABSTRACT OF THE RESEARCH PROJECT

    Directory of Open Access Journals (Sweden)

    Špela Smrkolj

    2018-02-01

    Full Text Available Background: Morbidity and mortality caused by cancer persist to be an important health problem world- wide and in the European Union member states as well. In Slovenia, most ovarian cancer cases are detected in advanced stages, hence a rather high mortality rate. Aims: The purpose of this research project is to analyze the primary cytoreduction in the patients with advanced ovarian cancer. The main objective of the project is to assess the use of lap- aroscopy in the prediction of optimal cytoreduction in these patients. Applicative research project ‘Estimation of survial in patients with advanced ovarian can- cer based on primary laparoscopical assessment of optimal cytoreduction’ (L3-2371 was approved and has been financed by the Slovene Research Agency and co-financed by the Ministry of Health of RS; Duration: May 1, 2009–April 30, 2012. Methods: The research project will consist of retrospective and prospective study. In all the patients with advanced ovarian cancer managed at the Department of Obstetrics and Gynecol- ogy, University Medical Centre Ljubljana in the years 2003–2008, and in whom optimal primary cytoreduction was made using either laparoscopy or laparotomy, certain clinical and pathomorphological factors will be compared, and the effects of all analyzed factors on the outcome of treatment assessed. In the prospective study, we will aim at assessing the use of laparoscopy in the prediction of optimal cytoreduction in all newly detected cases using a laparoscopy-based score (Fagotti’s scoring system. Conclusions: The standard management of advanced ovarian cancer patients consists of primary surgical optimal and/or suboptimal cytoreduction followed by aggressive cytotoxic chemotherapy. In line with our experience and with that published most recently, laparoscopy seems to be a promising method with which we will attempt to most accurately assess the optimal cytoreduction in surgical treatment of ovarian cancer patients.

  10. Use of multivariate analysis to research career advancement of academic librarians

    Directory of Open Access Journals (Sweden)

    Filiberto Felipe Martínez Arellano

    2004-01-01

    Full Text Available Diverse variables dealing with credential factors, bureaucratiuc factors, organizational and disciplinary achievements, academic culture factors, social ascribed factors, and institutional factors were stated as explanatory elements of promotion, tenure status, and earnings. A survey was the research instrument for collecting data to test diverse variables dealing with academic librarians rewards and earnings. Since the study attempted to analyze variables in a multivariate context, variable interactions were tested using multiple regression analysis. Findings of this study contribute to a better understanding of those factors influencing career advancement of academic librarians. Likewise, research methodology of this study could be used in Library and Information Science(LIS research.

  11. Advanced alarm system design and human performance: Guidance development and current research

    Energy Technology Data Exchange (ETDEWEB)

    O` Hara, J M [Brookhaven National Lab., Upton, NY (United States)

    1997-09-01

    This paper describes a research program sponsored by the U.S. Nuclear Regulatory Commission to address the human factors engineering (HFE) aspects of nuclear power plant alarm systems. The overall objective of the program is to develop HFE review guidance for advanced alarm systems. Guidance has been developed based on a broad base of technical and research literature. As part of the development effort, aspects of alarm system design for which the technical basis was insufficient to support guidance development were identified and prioritized. Research is currently underway to address the highest priority topics: alarm processing and display characteristics. (author). 29 refs, 2 figs.

  12. U.S. Department of Energy instrumentation and controls technology research for advanced small modular reactors

    International Nuclear Information System (INIS)

    Wood, Richard Thomas

    2013-01-01

    Instrumentation, controls, and human-machine interfaces (ICHMI) are essential enabling technologies that strongly influence nuclear power plant performance and operational costs. The U.S. Department of Energy (DOE) has recognized that ICHMI research, development, and demonstration (RD and D) is needed to resolve the technical challenges that may compromise the effective and efficient utilization of modern ICHMI technology and consequently inhibit realization of the benefits offered by expanded utilization of nuclear power. Consequently, key DOE programs have substantial ICHMI RD and D elements to their respective research portfolio. This article describes current ICHMI research to support the development of advanced small modular reactors. (author)

  13. Advanced alarm system design and human performance: Guidance development and current research

    International Nuclear Information System (INIS)

    O'Hara, J.M.

    1997-01-01

    This paper describes a research program sponsored by the U.S. Nuclear Regulatory Commission to address the human factors engineering (HFE) aspects of nuclear power plant alarm systems. The overall objective of the program is to develop HFE review guidance for advanced alarm systems. Guidance has been developed based on a broad base of technical and research literature. As part of the development effort, aspects of alarm system design for which the technical basis was insufficient to support guidance development were identified and prioritized. Research is currently underway to address the highest priority topics: alarm processing and display characteristics. (author). 29 refs, 2 figs

  14. The rehabilitation engineering research center for the advancement of cognitive technologies.

    Science.gov (United States)

    Heyn, Patricia Cristine; Cassidy, Joy Lucille; Bodine, Cathy

    2015-02-01

    Barring few exceptions, allied health professionals, engineers, manufacturers of assistive technologies (ATs), and consumer product manufacturers have developed few technologies for individuals with cognitive impairments (CIs). In 2004, the National Institute on Disability Rehabilitation Research (NIDRR) recognized the need to support research in this emergent field. They funded the first Rehabilitation Engineering Research Center for the Advancement of Cognitive Technologies (RERC-ACT). The RERC-ACT has since designed and evaluated existing and emerging technologies through rigorous research, improving upon existing AT devices, and creating new technologies for individuals with CIs. The RERC-ACT has contributed to the development and testing of AT products that assist persons with CIs to actively engage in tasks of daily living at home, school, work, and in the community. This article highlights the RERC-ACT's engineering development and research projects and discusses how current research may impact the quality of life for an aging population. © The Author(s) 2014.

  15. Robotics research at Electrotechnical Laboratory-R and D program for advanced robot technology

    Energy Technology Data Exchange (ETDEWEB)

    Wakamatsu, S; Akahori, H; Shirai, Y; Kakikura, M

    1983-01-01

    The purposes of this paper are both to introduce the outline of robotics researches at Electrotechnical Laboratory and to describe the relation between those researches and the national project so called robotics for critical work. The authors first describe the robotics researches and related topics historically which have been continued from the latter half of 1960s as a part of researches on artificial intelligence at Electrotechnical Laboratory. Secondly, they mention the present aspects of our researches, its relation with past results, and changes of basic concepts on robotics systems. Finally, as an extension of our researches, they propose some approaches to establish the following techniques which make very important roles for the success of the national project; (1) manipulation techniques, (2) sensor techniques, (3) autonomous robot control techniques, (4) advanced tele-operation techniques and, (5) system totalizing techniques. 15 references.

  16. Compressed air noise reductions from using advanced air gun nozzles in research and development environments.

    Science.gov (United States)

    Prieve, Kurt; Rice, Amanda; Raynor, Peter C

    2017-08-01

    The aims of this study were to evaluate sound levels produced by compressed air guns in research and development (R&D) environments, replace conventional air gun models with advanced noise-reducing air nozzles, and measure changes in sound levels to assess the effectiveness of the advanced nozzles as engineering controls for noise. Ten different R&D manufacturing areas that used compressed air guns were identified and included in the study. A-weighted sound level and Z-weighted octave band measurements were taken simultaneously using a single instrument. In each area, three sets of measurements, each lasting for 20 sec, were taken 1 m away and perpendicular to the air stream of the conventional air gun while a worker simulated typical air gun work use. Two different advanced noise-reducing air nozzles were then installed. Sound level and octave band data were collected for each of these nozzles using the same methods as for the original air guns. Both of the advanced nozzles provided sound level reductions of about 7 dBA, on average. The highest noise reductions measured were 17.2 dBA for one model and 17.7 dBA for the other. In two areas, the advanced nozzles yielded no sound level reduction, or they produced small increases in sound level. The octave band data showed strong similarities in sound level among all air gun nozzles within the 10-1,000 Hz frequency range. However, the advanced air nozzles generally had lower noise contributions in the 1,000-20,000 Hz range. The observed decreases at these higher frequencies caused the overall sound level reductions that were measured. Installing new advanced noise-reducing air nozzles can provide large sound level reductions in comparison to existing conventional nozzles, which has direct benefit for hearing conservation efforts.

  17. Report of the evaluation by the Ad Hoc Review Committee on advance science research. Result evaluation, interim evaluation, in-advance evaluation in fiscal year 2003

    International Nuclear Information System (INIS)

    2003-11-01

    The Research Evaluation Committee, which consisted of 13 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Advanced Science Research in accordance with the Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the accomplishments of the research completed in Fiscal Year 2002, the accomplishments of the research started in Fiscal Year 2001, and the adequacy of the programs of the research to be started in Fiscal Year 2004 at Advanced Science Research Center of JAERI. The Ad Hoc Review Committee consisted of nine specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from May to July 2003. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on June 24, 2003, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on August 4, 2003. This report describes the result of the evaluation by the Ad Hoc Review Committee on Advanced Science Research. (author)

  18. Report of the evaluation by the Ad Hoc Review Committee on Advance Science Research. Result evaluation, interim evaluation, in-advance evaluation in fiscal year 2002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-11-01

    The Research Evaluation Committee, which consisted of 13 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Advanced Science Research in accordance with the Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the accomplishments of the research completed in Fiscal Year 2001, the accomplishments of the research started in Fiscal Year 2000, and the adequacy of the programs of the research to be started in Fiscal Year 2003 at Advanced Science Research Center of JAERI. The Ad Hoc Review Committee consisted of eight specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from May to July 2002. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on June 4, 2002, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on August 5, 2002. This report describes the result of the evaluation by the Ad Hoc Review Committee on Advanced Science Research. (author)

  19. Advances in the prevention of oral disease; the role of the International Association for Dental Research.

    Science.gov (United States)

    Whelton, Helen; Fox, Christopher

    2015-01-01

    Since its foundation in 1920, prevention of oral disease has been a priority for the International Association for Dental Research (IADR) and the commitment of the organisation to the subject area is clearly expressed in its mission to improve oral health worldwide. The IADR has a current global membership of almost 11,000 people who share an interest in oral and craniofacial research. This paper provides an overview of the contribution of IADR to supporting research and associated activities in disease prevention, in disseminating knowledge and in advocating for better oral health for all citizens of the world. It looks back over time and summarises current supports. Two more recent initiatives in disease prevention are described in more detail, the Global Oral Health Inequalities Research Agenda (GOHIRA) and the proceedings at the 2013 World Conference on Preventive Dentistry (WCPD, 2013), a joint initiative between IADR and WHO. Through organisational structure, meetings, publications, scientific groups and networks and external relations, IADR has been at the forefront of advancing research for the prevention of oral diseases. IADR is committed to ensuring research advances get disseminated and implemented and at the same time encourages and advocates for basic, clinical and translational research across disciplines so that we may uncover the major breakthrough in prevention of oral disease.

  20. Advanced fusion technology research and development. Annual report to the U.S. Department of Energy

    International Nuclear Information System (INIS)

    2001-01-01

    OAK-B135 The General Atomics (GA) Advanced Fusion Technology program seeks to advance the knowledge base needed for next-generation fusion experiments, and ultimately for an economical and environmentally attractive fusion energy source. To achieve this objective, they carry out fusion systems design studies to evaluate the technologies needed for next-step experiments and power plants, and they conduct research to develop basic and applied knowledge about these technologies. GA's Advanced Fusion Technology program derives from, and draws on, the physics and engineering expertise built up by many years of experience in designing, building, and operating plasma physics experiments. The technology development activities take full advantage of the GA DIII-D program, the DIII-D facility, the Inertial Confinement Fusion (ICF) program and the ICF Target Fabrication facility. The report summarizes GA's FY00 work in the areas of Fusion Power Plant Studies, Next Step Options, Advanced Liquid Plasma Facing Surfaces, Advanced Power Extraction Study, Plasma Interactive Materials, Radiation Testing of Magnetic Coil, Vanadium Component Demonstration, RF Technology, Inertial Fusion Energy Target Supply System, ARIES Integrated System Studies, and Spin-offs Brochure. The work in these areas continues to address many of the issues that must be resolved for the successful construction and operation of next-generation experiments and, ultimately, the development of safe, reliable, economic fusion power plants

  1. Uncovering the Boundary-spanning Role of Information Systems Research in Trans-Disciplinary Knowledge Advancement

    DEFF Research Database (Denmark)

    Liu, Fei; Lim, Eric T. K.; Tan, Chee-Wee

    2017-01-01

    Intrigued by the important yet underexplored inter-disciplinary impact of IS discipline, this study investigates the inter-disciplinary role played by IS discipline in trans-disciplinary knowledge advancement. To achieve this objective, this study firstly advanced a Model of Trans-Disciplinary Kn......Intrigued by the important yet underexplored inter-disciplinary impact of IS discipline, this study investigates the inter-disciplinary role played by IS discipline in trans-disciplinary knowledge advancement. To achieve this objective, this study firstly advanced a Model of Trans......-Disciplinary Knowledge Advancement that posits a process that consists of three stages of thesis, antithesis, and synthesis with two transitions, namely knowledge liquidization and crystallization, in two modes, namely boundary-reinforcing and boundary-spanning. In light of this model, this study conducted...... elicited. Results from an in-depth bibliographic analysis on these central articles shed light on four distinct trans-disciplinary roles (i.e., spanner, innovator, aggregator, and reinforcer) and trans-disciplinary characteristics of IS research....

  2. Research Advances of Social Security Problems in China —Visualization Research based on Bibliometrics

    Institute of Scientific and Technical Information of China (English)

    赵琳

    2016-01-01

    This article summarized the research progress and characteristics of Chinese social security issues from 2000 papers, which record in CNKI. We find that, the topic in the field of social security is board and dispersion. Due to the huge system and complex problem of social security, there is no central theme. Through cluster analysis, multi dimensional scaling analysis and social network analysis, we got the high frequency keywords atlas. Then, we summarized the research topic to six parts. They are rural social security, urban and rural social security co-ordination, vulnerable group social security, social security fund management, the social insurance system, and social security system and government responsibility. It summed up the theme of the module, meanwhile, combined the practice analysis.

  3. Optimizing meridional advection of the Advanced Research WRF (ARW) dynamics for Intel Xeon Phi coprocessor

    Science.gov (United States)

    Mielikainen, Jarno; Huang, Bormin; Huang, Allen H.-L.

    2015-05-01

    The most widely used community weather forecast and research model in the world is the Weather Research and Forecast (WRF) model. Two distinct varieties of WRF exist. The one we are interested is the Advanced Research WRF (ARW) is an experimental, advanced research version featuring very high resolution. The WRF Nonhydrostatic Mesoscale Model (WRF-NMM) has been designed for forecasting operations. WRF consists of dynamics code and several physics modules. The WRF-ARW core is based on an Eulerian solver for the fully compressible nonhydrostatic equations. In the paper, we optimize a meridional (north-south direction) advection subroutine for Intel Xeon Phi coprocessor. Advection is of the most time consuming routines in the ARW dynamics core. It advances the explicit perturbation horizontal momentum equations by adding in the large-timestep tendency along with the small timestep pressure gradient tendency. We will describe the challenges we met during the development of a high-speed dynamics code subroutine for MIC architecture. Furthermore, lessons learned from the code optimization process will be discussed. The results show that the optimizations improved performance of the original code on Xeon Phi 7120P by a factor of 1.2x.

  4. Optimizing zonal advection of the Advanced Research WRF (ARW) dynamics for Intel MIC

    Science.gov (United States)

    Mielikainen, Jarno; Huang, Bormin; Huang, Allen H.

    2014-10-01

    The Weather Research and Forecast (WRF) model is the most widely used community weather forecast and research model in the world. There are two distinct varieties of WRF. The Advanced Research WRF (ARW) is an experimental, advanced research version featuring very high resolution. The WRF Nonhydrostatic Mesoscale Model (WRF-NMM) has been designed for forecasting operations. WRF consists of dynamics code and several physics modules. The WRF-ARW core is based on an Eulerian solver for the fully compressible nonhydrostatic equations. In the paper, we will use Intel Intel Many Integrated Core (MIC) architecture to substantially increase the performance of a zonal advection subroutine for optimization. It is of the most time consuming routines in the ARW dynamics core. Advection advances the explicit perturbation horizontal momentum equations by adding in the large-timestep tendency along with the small timestep pressure gradient tendency. We will describe the challenges we met during the development of a high-speed dynamics code subroutine for MIC architecture. Furthermore, lessons learned from the code optimization process will be discussed. The results show that the optimizations improved performance of the original code on Xeon Phi 5110P by a factor of 2.4x.

  5. Essay: Robert H. Siemann As Leader of the Advanced Accelerator Research Department

    Energy Technology Data Exchange (ETDEWEB)

    Colby, Eric R.; Hogan, Mark J.; /SLAC

    2011-11-14

    Robert H. Siemann originally conceived of the Advanced Accelerator Research Department (AARD) as an academic, experimental group dedicated to probing the technical limitations of accelerators while providing excellent educational opportunities for young scientists. The early years of the Accelerator Research Department B, as it was then known, were dedicated to a wealth of mostly student-led experiments to examine the promise of advanced accelerator techniques. High-gradient techniques including millimeter-wave rf acceleration, beam-driven plasma acceleration, and direct laser acceleration were pursued, including tests of materials under rf pulsed heating and short-pulse laser radiation, to establish the ultimate limitations on gradient. As the department and program grew, so did the motivation to found an accelerator research center that brought experimentalists together in a test facility environment to conduct a broad range of experiments. The Final Focus Test Beam and later the Next Linear Collider Test Accelerator provided unique experimental facilities for AARD staff and collaborators to carry out advanced accelerator experiments. Throughout the evolution of this dynamic program, Bob maintained a department atmosphere and culture more reminiscent of a university research group than a national laboratory department. His exceptional ability to balance multiple roles as scientist, professor, and administrator enabled the creation and preservation of an environment that fostered technical innovation and scholarship.

  6. The conceptual design of the standard and the reduced fuel assemblies for an advanced research reactor

    International Nuclear Information System (INIS)

    Ryu, Jeong Soo; Cho, Yeong Garp; Yoon, Doo Byung; Dan, Ho Jin; Chae, Hee Tack; Park, Cheol

    2005-01-01

    HANARO (Hi-flux Advanced Neutron Application Reactor), is an open-tank-in-pool type research reactor with a thermal power of 30MW. The HANARO has been operating at Korea Atomic Energy Research Institute since 1995. Based on the technical experiences in design and operation for the HANARO, the design of an Advanced Research Reactor (ARR) was launched by KAERI in 2002. The final goal of the project is to develop a new and advanced research reactor model which is superior in safety and economical aspects. This paper summarizes the design improvements of the conceptually designed standard fuel assembly based on the analysis results for the nuclear physics. It includes also the design of the reduced fuel assembly in conjunction with the flow tube as the fuel channel and the guide of the absorber rod. In the near future, the feasibility of the conceptually designed fuel assemblies of the ARR will be verified by investigating the dynamic and the thermal behaviors of the fuel assembly submerged in coolant

  7. Essay: Robert H. Siemann As Leader of the Advanced Accelerator Research Department

    International Nuclear Information System (INIS)

    Colby, Eric R.; Hogan, Mark J.

    2008-01-01

    Robert H. Siemann originally conceived of the Advanced Accelerator Research Department (AARD) as an academic, experimental group dedicated to probing the technical limitations of accelerators while providing excellent educational opportunities for young scientists. The early years of the Accelerator Research Department B, as it was then known, were dedicated to a wealth of mostly student-led experiments to examine the promise of advanced accelerator techniques. High-gradient techniques including millimeter-wave rf acceleration, beam-driven plasma acceleration, and direct laser acceleration were pursued, including tests of materials under rf pulsed heating and short-pulse laser radiation, to establish the ultimate limitations on gradient. As the department and program grew, so did the motivation to found an accelerator research center that brought experimentalists together in a test facility environment to conduct a broad range of experiments. The Final Focus Test Beam and later the Next Linear Collider Test Accelerator provided unique experimental facilities for AARD staff and collaborators to carry out advanced accelerator experiments. Throughout the evolution of this dynamic program, Bob maintained a department atmosphere and culture more reminiscent of a university research group than a national laboratory department. His exceptional ability to balance multiple roles as scientist, professor, and administrator enabled the creation and preservation of an environment that fostered technical innovation and scholarship.

  8. Building capacity for public and population health research in Africa: the consortium for advanced research training in Africa (CARTA) model

    Science.gov (United States)

    Ezeh, Alex C.; Izugbara, Chimaraoke O.; Kabiru, Caroline W.; Fonn, Sharon; Kahn, Kathleen; Manderson, Lenore; Undieh, Ashiwel S.; Omigbodun, Akinyinka; Thorogood, Margaret

    2010-01-01

    Background Globally, sub-Saharan Africa bears the greatest burden of disease. Strengthened research capacity to understand the social determinants of health among different African populations is key to addressing the drivers of poor health and developing interventions to improve health outcomes and health systems in the region. Yet, the continent clearly lacks centers of research excellence that can generate a strong evidence base to address the region's socio-economic and health problems. Objective and program overview We describe the recently launched Consortium for Advanced Research Training in Africa (CARTA), which brings together a network of nine academic and four research institutions from West, East, Central, and Southern Africa, and select northern universities and training institutes. CARTA's program of activities comprises two primary, interrelated, and mutually reinforcing objectives: to strengthen research infrastructure and capacity at African universities; and to support doctoral training through the creation of a collaborative doctoral training program in population and public health. The ultimate goal of CARTA is to build local research capacity to understand the determinants of population health and effectively intervene to improve health outcomes and health systems. Conclusions CARTA's focus on the local production of networked and high-skilled researchers committed to working in sub-Saharan Africa, and on the concomitant increase in local research and training capacity of African universities and research institutes addresses the inability of existing programs to create a critical mass of well-trained and networked researchers across the continent. The initiative's goal of strengthening human resources and university-wide systems critical to the success and sustainability of research productivity in public and population health will rejuvenate institutional teaching, research, and administrative systems. PMID:21085517

  9. Building capacity for public and population health research in Africa: the consortium for advanced research training in Africa (CARTA model

    Directory of Open Access Journals (Sweden)

    Alex C. Ezeh

    2010-11-01

    Full Text Available Background: Globally, sub-Saharan Africa bears the greatest burden of disease. Strengthened research capacity to understand the social determinants of health among different African populations is key to addressing the drivers of poor health and developing interventions to improve health outcomes and health systems in the region. Yet, the continent clearly lacks centers of research excellence that can generate a strong evidence base to address the region's socio-economic and health problems. Objective and program overview: We describe the recently launched Consortium for Advanced Research Training in Africa (CARTA, which brings together a network of nine academic and four research institutions from West, East, Central, and Southern Africa, and select northern universities and training institutes. CARTA's program of activities comprises two primary, interrelated, and mutually reinforcing objectives: to strengthen research infrastructure and capacity at African universities; and to support doctoral training through the creation of a collaborative doctoral training program in population and public health. The ultimate goal of CARTA is to build local research capacity to understand the determinants of population health and effectively intervene to improve health outcomes and health systems. Conclusions: CARTA's focus on the local production of networked and high-skilled researchers committed to working in sub-Saharan Africa, and on the concomitant increase in local research and training capacity of African universities and research institutes addresses the inability of existing programs to create a critical mass of well-trained and networked researchers across the continent. The initiative's goal of strengthening human resources and university-wide systems critical to the success and sustainability of research productivity in public and population health will rejuvenate institutional teaching, research, and administrative systems.

  10. Fiscal 2000 pioneering research report on the research on advanced safety helicopter; 2000 nendo advanced safety helicopter no chosa kenkyu hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    A survey was conducted concerning helicopter operating environments and the trends of related technologies in Japan and abroad, and the needs and seeds were grasped. Research was made to study technical problems and measures to solve them for the development of a safe, low-noise, and low-cost next-generation advanced safety helicopter (ASH). A market research was conducted on traffic systems in the future, state of aviation-related infrastructures and their future, current state of people's daily life which centers about locomotion, and the effect that ASH would impose on society. A technical research was carried out relative to flight safety, which involved EVS (enhanced vision system), information display system for helicopters, collision avoidance advisory for pilots, air collision prevention system/surveillance system for helicopters, obstacle detection/warning system for helicopters, blade deicing system for helicopters, and so forth. Detailed investigations were also conducted for technologies for reduction in the manufacturing, maintenance, and development costs, and for reduction in noise. (NEDO)

  11. Report of the evaluation by the ad hoc review committee on advanced photon and synchrotron radiation research. In-advance evaluation in fiscal year 2001

    International Nuclear Information System (INIS)

    2001-11-01

    The Research Evaluation Committee, which consisted of 13 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Advanced Photon and Synchrotron Radiation Research in accordance with the 'Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the adequacy of the R and D programs to be implemented for five years starting in Fiscal Year 2002 at Advanced Photon Research Center and at Synchrotron Radiation Research Center in Kansai Research Establishment of JAERI. The Ad Hoc Review Committee consisted of ten specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from May to July 2001. The evaluation was performed on the basis of the materials submitted in advanced and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on June 21, 2001, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on July 12, 2001. This report describes the result of the evaluation by the Ad Hoc Review Committee on Advanced Photon and Synchrotron Radiation Research. (author)

  12. Proceedings of the fourth international symposium on advanced nuclear energy research

    International Nuclear Information System (INIS)

    1992-12-01

    The papers presented and discussed in the 4th International Symposium on Advanced Nuclear Energy Research, of which subject was focussed on the Roles and Direction of Material Science in Nuclear Technology are contained. The sessions organized for the aural session of the symposium were (1) Processing Science for New Materials, (2) New Tools for Advanced Materials Research, (3) Challenge of Materials Database and (4) Frontier of Materials Technology in New Power Systems, from which 18 invited and 77 contributed papers were selected for the publication. The volume includes also summaries of the panel discussions titled as (1) Computer Simulation for Materials Innovation and (2) What is Expected for Materials Science in Future Nuclear Energy Developments ?, with which a complete recording of the discussions for the latter subject was attempted by the Editorial Working Group of the Program Committee. The 65 of the presented papers are indexed individually. (J.P.N.)

  13. Research advances in sorafenib-induced apoptotic signaling pathways in liver cancer cells

    Directory of Open Access Journals (Sweden)

    ZHANG Chaoya

    2016-04-01

    Full Text Available Currently, sorafenib is the multi-target inhibitor for the treatment of advanced primary liver cancer, and can effectively prolong the progression-free survival and overall survival in patients with advanced primary liver cancer. The application of sorafenib in the targeted therapy for liver cancer has become a hot topic. Major targets or signaling pathways include Raf/Mek/Erk, Jak/Stat, PI3K/Akt/mTOR, VEGFR and PDGFR, STAT, microRNA, Wnt/β-catenin, autolysosome, and tumor-related proteins, and sorafenib can regulate the proliferation, differentiation, metastasis, and apoptosis of liver cancer cells through these targets. This article reviews the current research on the action of sorafenib on these targets or signaling pathways to provide useful references for further clinical research on sorafenib.

  14. NATO Advanced Research Workshop on Frontiers of High-Pressure Research

    CERN Document Server

    Etters, Richard

    1991-01-01

    The role of high pressure experiments in the discovery of supercon­ ducting materials with a T. above liquid nitrogen temperature has demon­ strated the importance of such experiments. The same role holds true in the tailoring of materials for optoelectronic devices. In addition, much progress has been made recently in the search for metallic hydro­ gen, and the application of high pressure in polymer research has brought forth interesting results. These facts together with the suc­ cess of previous small size meetings (such as the "First International Conference on the Physics of Solids at High Pressure", held in 1965 in Tucson, Arizona, U. S. A. ; "High Pressure and Low Temperature Physics", held in 1977 in Cleveland, Ohio, U. S. A. ; and "Physics of Solids Under High Pressure", held in 1981 in bad Honnef, Germany), motivated us to organize a workshop with emphasis on the newest results and trends in these fields of high pressure research. Furthermore, it was intended to mix experienced and young scien�...

  15. WPA ISSPD educational program: Module II. Advances in research and understanding of personality disorders

    DEFF Research Database (Denmark)

    Ronningstam, Elsa; Simonsen, Erik; Millon, Theodore

    2009-01-01

    of their heritability and aetiological origin, variability over time and between cultures, and change and remission. A curriculum suggesting different educational approaches to the programme, now available on the Internet, aims at promoting integrative learning and discussion among clinicians and educators in study......Recent advances in research, clinical observations and treatment have contributed to several major changes in the conceptualization of personality disorders. Featured in an educational programme on personality disorders prepared by the World Psychiatric Association (WPA) Section on Personality...

  16. 2011 NDIA Advanced Research Projects Agency - Energy/DoD Workshop

    Science.gov (United States)

    2011-09-12

    for Handoffs Advanced Research Projects Agency • Energy Portfolio of Projects UNIVERSITY/ LAB SMALL BUSINESS CORPORATION Fuel-Free Isothermal...2011 Present Programs • Agile Delivery of Electrical Power Technology (ADEPT) • Batteries for Electrical Energy Storage in Transportation ( BEEST ...Technologies for Energy (REACT) • Solar Agile Delivery of Electrical Power Technology (Solar – ADEPT) The BEEST : An Overview of ARPA-E’s Program in Ultra-High

  17. Early Student Support for Application of Advanced Multi-Core Processor Technologies to Oceanographic Research

    Science.gov (United States)

    2016-05-07

    REPORT DOCUMENTATION PAGE I . ... ... .. . ,...,.., ............. OMB No. 0704-0188 The public reporting burden for this collection of...Student Support for Appl ication of Advanced Multi- Core Processor N00014-12-1-0298 Technologies to Oceanographic Research Sb. GRANT NUMBER Sc...communications protocols (i.e. UART, I2C, and SPI), through the , ’ . handing off of the data to the server APis. By providing a common set of tools

  18. Acquisition of Cooperative Small Unmanned Aerial Systems for Advancing Man Machine Interface Research

    Science.gov (United States)

    2016-08-24

    Airborne Cross Runway Departure/Landing Scenario Figure 7 Illustration of a participant looking at the 10Hz or 15Hz flickering visual stimulus in a...Figure 5 An illustration using a formation of UAVs for Direction of Arrival (DOA) mitigation of spoofing signals Spoofer Antenna array based on a...this project is to research and develop robust and jamming-resistant receivers including advanced interference mitigation algorithms and network

  19. Setting health research priorities using the CHNRI method: IV. Key conceptual advances.

    Science.gov (United States)

    Rudan, Igor

    2016-06-01

    Child Health and Nutrition Research Initiative (CHNRI) started as an initiative of the Global Forum for Health Research in Geneva, Switzerland. Its aim was to develop a method that could assist priority setting in health research investments. The first version of the CHNRI method was published in 2007-2008. The aim of this paper was to summarize the history of the development of the CHNRI method and its key conceptual advances. The guiding principle of the CHNRI method is to expose the potential of many competing health research ideas to reduce disease burden and inequities that exist in the population in a feasible and cost-effective way. The CHNRI method introduced three key conceptual advances that led to its increased popularity in comparison to other priority-setting methods and processes. First, it proposed a systematic approach to listing a large number of possible research ideas, using the "4D" framework (description, delivery, development and discovery research) and a well-defined "depth" of proposed research ideas (research instruments, avenues, options and questions). Second, it proposed a systematic approach for discriminating between many proposed research ideas based on a well-defined context and criteria. The five "standard" components of the context are the population of interest, the disease burden of interest, geographic limits, time scale and the preferred style of investing with respect to risk. The five "standard" criteria proposed for prioritization between research ideas are answerability, effectiveness, deliverability, maximum potential for disease burden reduction and the effect on equity. However, both the context and the criteria can be flexibly changed to meet the specific needs of each priority-setting exercise. Third, it facilitated consensus development through measuring collective optimism on each component of each research idea among a larger group of experts using a simple scoring system. This enabled the use of the knowledge of

  20. NIH Roundtable on Opportunities to Advance Research on Neurologic and Psychiatric Emergencies.

    Science.gov (United States)

    D'Onofrio, Gail; Jauch, Edward; Jagoda, Andrew; Allen, Michael H; Anglin, Deirdre; Barsan, William G; Berger, Rachel P; Bobrow, Bentley J; Boudreaux, Edwin D; Bushnell, Cheryl; Chan, Yu-Feng; Currier, Glenn; Eggly, Susan; Ichord, Rebecca; Larkin, Gregory L; Laskowitz, Daniel; Neumar, Robert W; Newman-Toker, David E; Quinn, James; Shear, Katherine; Todd, Knox H; Zatzick, Douglas

    2010-11-01

    The Institute of Medicine Committee on the Future of Emergency Care in the United States Health System (2003) identified a need to enhance the research base for emergency care. As a result, a National Institutes of Health (NIH) Task Force on Research in Emergency Medicine was formed to enhance NIH support for emergency care research. Members of the NIH Task Force and academic leaders in emergency care participated in 3 Roundtable discussions to prioritize current opportunities for enhancing and conducting emergency care research. We identify key research questions essential to advancing the science of emergency care and discuss the barriers and strategies to advance research by exploring the collaboration between NIH and the emergency care community. Experts from emergency medicine, neurology, psychiatry, and public health assembled to review critical areas in need of investigation, current gaps in knowledge, barriers, and opportunities. Neurologic emergencies included cerebral resuscitation, pain, stroke, syncope, traumatic brain injury, and pregnancy. Mental health topics included suicide, agitation and delirium, substances, posttraumatic stress, violence, and bereavement. Presentations and group discussion firmly established the need for translational research to bring basic science concepts into the clinical arena. A coordinated continuum of the health care system that ensures rapid identification and stabilization and extends through discharge is necessary to maximize overall patient outcomes. There is a paucity of well-designed, focused research on diagnostic testing, clinical decisionmaking, and treatments in the emergency setting. Barriers include the limited number of experienced researchers in emergency medicine, limited dedicated research funding, and difficulties of conducting research in chaotic emergency environments stressed by crowding and limited resources. Several themes emerged during the course of the roundtable discussion, including the need

  1. Enhancing research publications and advancing scientific writing in health research collaborations: sharing lessons learnt from the trenches.

    Science.gov (United States)

    Li, Guowei; Jin, Yanling; Mbuagbaw, Lawrence; Dolovich, Lisa; Adachi, Jonathan D; Levine, Mitchell Ah; Cook, Deborah; Samaan, Zainab; Thabane, Lehana

    2018-01-01

    Disseminating research protocols, processes, methods or findings via peer-reviewed publications has substantive merits and benefits to various stakeholders. In this article, we share strategies to enhance research publication contents (ie, what to write about) and to facilitate scientific writing (ie, how to write) in health research collaborations. Empirical experience sharing. To enhance research publication contents, we encourage identifying appropriate opportunities for publications, publishing protocols ahead of results papers, seeking publications related to methodological issues, considering justified secondary analyses, and sharing academic process or experience. To advance writing, we suggest setting up scientific writing as a goal, seeking an appropriate mentorship, making full use of scientific meetings and presentations, taking some necessary formal training in areas such as effective communication and time and stress management, and embracing the iterative process of writing. All the strategies we share are dependent upon each other; and they advocate gradual academic accomplishments through study and training in a "success-breeds-success" way. It is expected that the foregoing shared strategies in this paper, together with other previous guidance articles, can assist one with enhancing research publications, and eventually one's academic success in health research collaborations.

  2. [Advances in research of chemical constituents and pharmacological activites of Bauhinia].

    Science.gov (United States)

    Shang, Xiao-Ya; Liu, Wei; Zhao, Cong-Wei

    2008-03-01

    The research advances based on the related references were summarized in the last thirty years. Bauhinia contained many kinds of chemical constituents, primarily including flavanoids, steroids, terpenoid and so on, some of them were firstly obtained from the nature. Many plants of the Bauhinia are used in traditional medicine for their interesting biological activities such as antidiabetic, antiinflammatory, antimicrobial, analgesic, astringent and diuretic effects. This paper gives an overview of phytochemical and pharmacological research in Bauhinia, and it has been classified accordding to the chemical structure characteristics. To provide more material to draw on for further development and utilization resources of Bauhinia.

  3. Automatic braking system modification for the Advanced Transport Operating Systems (ATOPS) Transportation Systems Research Vehicle (TSRV)

    Science.gov (United States)

    Coogan, J. J.

    1986-01-01

    Modifications were designed for the B-737-100 Research Aircraft autobrake system hardware of the Advanced Transport Operating Systems (ATOPS) Program at Langley Research Center. These modifications will allow the on-board flight control computer to control the aircraft deceleration after landing to a continuously variable level for the purpose of executing automatic high speed turn-offs from the runway. A bread board version of the proposed modifications was built and tested in simulated stopping conditions. Test results, for various aircraft weights, turnoff speed, winds, and runway conditions show that the turnoff speeds are achieved generally with errors less than 1 ft/sec.

  4. Subsonic Ultra Green Aircraft Research Phase II: N+4 Advanced Concept Development

    Science.gov (United States)

    Bradley, Marty K.; Droney, Christopher K.

    2012-01-01

    This final report documents the work of the Boeing Subsonic Ultra Green Aircraft Research (SUGAR) team on Task 1 of the Phase II effort. The team consisted of Boeing Research and Technology, Boeing Commercial Airplanes, General Electric, and Georgia Tech. Using a quantitative workshop process, the following technologies, appropriate to aircraft operational in the N+4 2040 timeframe, were identified: Liquefied Natural Gas (LNG), Hydrogen, fuel cell hybrids, battery electric hybrids, Low Energy Nuclear (LENR), boundary layer ingestion propulsion (BLI), unducted fans and advanced propellers, and combinations. Technology development plans were developed.

  5. Practical and Ethical Aspects of Advance Research Directives for Research on Healthy Aging: German and Israeli Professionals' Perspectives.

    Science.gov (United States)

    Werner, Perla; Schicktanz, Silke

    2018-01-01

    Healthy aging is the development and maintenance of optimal cognitive, social and physical well-being, and function in older adults. Preventing or minimizing disease is one of the main ways of achieving healthy aging. Dementia is one of the most prevalent and life-changing diseases of old age. Thus, dementia prevention research is defined as one of the main priorities worldwide. However, conducting research with persons who lack the capacity to give consent is a major ethical issue. Our study attempts to explore if and how advance research directives (ARDs) may be used as a future tool to deal with the ethical and practical issues in dementia research. We conducted focus groups and in-depth interviews with German and Israeli professional stakeholders from the fields of gerontology, ethics, medical law, psychiatry, neurology and policy advice ( n  = 16), and analyzed the main topics discussed regarding cross-national similarities and controversies within the groups, as well as across the two national contexts. While both countries are in the midst of a developmental process and have recognized the importance and need for ARD as a tool for expanding healthy aging, Germany is in a more advanced stage than Israel because of the EU regulation process, which indicates the influence of international harmonization on these research-related ethical issues. Consensual themes within the qualitative material were identified: the need for a broader debate on ARD, the ethical importance of autonomy and risk-benefit assessment for ARD implementation, the role of the proxy and the need for the differentiation of types of dementia research. Controversies and dilemmas aroused around themes such as the current role of IRBs in each country, the need for limits, and how to guaranty safeguarding and control. Implementing a new tool is a step-by-step procedure requiring a thorough understanding of the current state of knowledge as well as of the challenges and hurdles ahead. As long

  6. Practical and Ethical Aspects of Advance Research Directives for Research on Healthy Aging: German and Israeli Professionals’ Perspectives

    Directory of Open Access Journals (Sweden)

    Perla Werner

    2018-04-01

    Full Text Available BackgroundHealthy aging is the development and maintenance of optimal cognitive, social and physical well-being, and function in older adults. Preventing or minimizing disease is one of the main ways of achieving healthy aging. Dementia is one of the most prevalent and life-changing diseases of old age. Thus, dementia prevention research is defined as one of the main priorities worldwide. However, conducting research with persons who lack the capacity to give consent is a major ethical issue.ObjectiveOur study attempts to explore if and how advance research directives (ARDs may be used as a future tool to deal with the ethical and practical issues in dementia research.MethodWe conducted focus groups and in-depth interviews with German and Israeli professional stakeholders from the fields of gerontology, ethics, medical law, psychiatry, neurology and policy advice (n = 16, and analyzed the main topics discussed regarding cross-national similarities and controversies within the groups, as well as across the two national contexts.ResultsWhile both countries are in the midst of a developmental process and have recognized the importance and need for ARD as a tool for expanding healthy aging, Germany is in a more advanced stage than Israel because of the EU regulation process, which indicates the influence of international harmonization on these research-related ethical issues. Consensual themes within the qualitative material were identified: the need for a broader debate on ARD, the ethical importance of autonomy and risk–benefit assessment for ARD implementation, the role of the proxy and the need for the differentiation of types of dementia research. Controversies and dilemmas aroused around themes such as the current role of IRBs in each country, the need for limits, and how to guaranty safeguarding and control.DiscussionImplementing a new tool is a step-by-step procedure requiring a thorough understanding of the current state of knowledge

  7. Research Institute for Advanced Computer Science: Annual Report October 1998 through September 1999

    Science.gov (United States)

    Leiner, Barry M.; Gross, Anthony R. (Technical Monitor)

    1999-01-01

    The Research Institute for Advanced Computer Science (RIACS) carries out basic research and technology development in computer science, in support of the National Aeronautics and Space Administration's missions. RIACS is located at the NASA Ames Research Center (ARC). It currently operates under a multiple year grant/cooperative agreement that began on October 1, 1997 and is up for renewal in the year 2002. ARC has been designated NASA's Center of Excellence in Information Technology. In this capacity, ARC is charged with the responsibility to build an Information Technology Research Program that is preeminent within NASA. RIACS serves as a bridge between NASA ARC and the academic community, and RIACS scientists and visitors work in close collaboration with NASA scientists. RIACS has the additional goal of broadening the base of researchers in these areas of importance to the nation's space and aeronautics enterprises. RIACS research focuses on the three cornerstones of information technology research necessary to meet the future challenges of NASA missions: (1) Automated Reasoning for Autonomous Systems. Techniques are being developed enabling spacecraft that will be self-guiding and self-correcting to the extent that they will require little or no human intervention. Such craft will be equipped to independently solve problems as they arise, and fulfill their missions with minimum direction from Earth. (2) Human-Centered Computing. Many NASA missions require synergy between humans and computers, with sophisticated computational aids amplifying human cognitive and perceptual abilities; (3) High Performance Computing and Networking Advances in the performance of computing and networking continue to have major impact on a variety of NASA endeavors, ranging from modeling and simulation to data analysis of large datasets to collaborative engineering, planning and execution. In addition, RIACS collaborates with NASA scientists to apply information technology research to

  8. Co-Operative Advances in Behavioral Health and Performance Research and Operations

    Science.gov (United States)

    VanderArk, Stephen T.; Leveton, Lauren B.

    2011-01-01

    In organizations that engage in both operations and applied research, with operational needs guiding research questions and research informing improved operations, the ideal goal is a synergy of ideas and information. In reality, this ideal synergy is often lacking. Real-time operational needs driving day-to-day decisions, lack of communication, lag time in getting research advances plugged into operations can cause both areas to suffer from this gap between operations and research. At Johnson Space Center, the Behavior Health and Performance group (BHP) strives to bridge this gap by following a Human Research Program framework: Expectations of future operational needs identify the knowledge gaps; the gaps in turn guide research leading to a product that is transitioned into operations. Thus, the direction those of us in research take is in direct response to current and future needs of operations. Likewise, those of us in operations actively seek knowledge that is supported by evidence-based research. We make an ongoing effort to communicate across the research and operations gap by working closely with each other and making a conscious effort to keep each other informed. The objective of the proposed panel discussion is to demonstrate through the following presentations the results of a successful collaboration between research and operations and to provide ASMA members with more practical knowledge and strategies for building these bridges to serve our field of practice well. The panel will consist of six presenters from BHP operations, internal BHP research, and external research instigated by BHP who together represent the entire BHP Research Transition to Operations Framework

  9. Status of NASA's Advanced Radioisotope Power Conversion Technology Research and Development

    Science.gov (United States)

    Wong, Wayne A.; Anderson, David J.; Tuttle, Karen L.; Tew, Roy C.

    2006-01-01

    NASA s Advanced Radioisotope Power Systems (RPS) development program is funding the advancement of next generation power conversion technologies that will enable future missions that have requirements that can not be met by either the ubiquitous photovoltaic systems or by current Radioisotope Power Systems (RPS). Requirements of advanced radioisotope power systems include high efficiency and high specific power (watts/kilogram) in order to meet mission requirements with less radioisotope fuel and lower mass. Other Advanced RPS development goals include long-life, reliability, and scalability so that these systems can meet requirements for a variety of future space applications including continual operation surface missions, outer-planetary missions, and solar probe. This paper provides an update on the Radioisotope Power Conversion Technology Project which awarded ten Phase I contracts for research and development of a variety of power conversion technologies consisting of Brayton, Stirling, thermoelectrics, and thermophotovoltaics. Three of the contracts continue during the current Phase II in the areas of thermoelectric and Stirling power conversion. The accomplishments to date of the contractors, project plans, and status will be summarized.

  10. A preliminary exploration of Advanced Molecular Bio-Sciences Research Center

    International Nuclear Information System (INIS)

    Yamada, Yutaka; Yanai, Takanori; Onodera, Jun'ichi; Yamagami, Mutsumi; Sakata, Hiroshi; Sota, Masahiro; Takemura, Tatsuo; Koyama, Kenji; Sato, Fumiaki

    2000-01-01

    Low-dose and low-dose-rate radiation effects on life-span, pathological changes, hemopoiesis and cytokine production in experimental animals have been investigated in our laboratory. In the intermediate period of the investigation, an expert committee on radiation biology, which was composed of two task groups, was organized. The purposes of the committee were to assess of previous studies and plan future research for Advanced Molecular Bio-Sciences Research Center (AMBIC). In its report, the committee emphasized the necessity of molecular research in radiation biology and ecology, and proposed six subjects for the research: 1) Molecular carcinogenesis of low-dose radiation; 2) Radiation effects on the immune system and hemopoietic system; 3) Molecular mechanisms of hereditary effect; 4) Non cancer effect of low-dose radiation; 5) Gene targeting for ion transport system in plants; 6) Bioremediation with transgenic plant and bacteria. Exploration of the AMBIC project will continue under the committee's direction. (author)

  11. Mobility disorders and pain, interrelations that need new research concepts and advanced clinical commitments

    Directory of Open Access Journals (Sweden)

    Sascha Sajer

    2017-12-01

    Full Text Available This Perspective will discuss topics recently suggested by Prof. Helmut Kern, Vienna, Austria, to advance the research activities of his team, that is: Topic A, 10 years post RISE; Topic B, New research for new solutions on old research questions; Topic C, Working groups on nerve regeneration, training-parameters of seniors in different ages, muscle adaptation; and studies of connective tissue and cartilage. This Perspective summarizes some of the basic concepts and of the evidence-based tools for developing further translational research activities. Clinically relevant results will ask for continuous interests of Basic and Applied Myologists and for the support during the next five to ten years of public and private granting agencies. All together, they will end in protocols, devices and multidisciplinary managements for persons suffering with muscle denervation, neuromuscular-related or non-related pain and for the increasing population of old, older and oldest senior citizens in Europe and beyond.

  12. Advancing Evidence-Based Assessment in School Mental Health: Key Priorities for an Applied Research Agenda.

    Science.gov (United States)

    Arora, Prerna G; Connors, Elizabeth H; George, Melissa W; Lyon, Aaron R; Wolk, Courtney B; Weist, Mark D

    2016-12-01

    Evidence-based assessment (EBA) is a critically important aspect of delivering high-quality, school-based mental health care for youth. However, research in this area is limited and additional applied research on how best to support the implementation of EBA in school mental health (SMH) is needed. Accordingly, this manuscript seeks to facilitate the advancement of research on EBA in SMH by reviewing relevant literature on EBA implementation in schools and providing recommendations for key research priorities. Given the limited number of published studies available, findings from child and adolescent mental health and implementation science research are also included to inform a robust and comprehensive research agenda on this topic. Based on this literature review, five priorities for research on EBA in SMH are outlined: (1) effective identification of assessment targets, (2) appropriate selection of assessment measures, (3) investigation of organizational readiness for EBA, (4) study of implementation support for EBA, and (5) promotion of EBA data integration and use. Each priority area includes recommended directions for future research. A comprehensive and robust research agenda is warranted to build the science and practice of implementing EBA in SMH. Specific directions for this agenda are offered.

  13. Effects of marital conflict on children: recent advances and emerging themes in process-oriented research.

    Science.gov (United States)

    Cummings, E Mark; Davies, Patrick T

    2002-01-01

    The effects of marital conflict on children's adjustment are well documented. For the past decade research has increasingly focused on advancing a process-level understanding of these effects, that is, accounting for the particular responses and patterns embedded within specific contexts, histories, and developmental periods that account for children's outcomes over time. As a vehicle for presenting an update, this review follows the framework for process-oriented research initially proposed by Cummings and Cummings (1988), concentrating on recent research developments, and also considering new and emerging themes in this area of research. In this regard, areas of advancement include (a) greater articulation of the effects of specific context/stimulus characteristics of marital conflict, (b) progress in identifying the psychological response processes in children (e.g., cognitive, emotional, social, physiological) that are affected and their possible role in accounting for relations between marital conflict and child outcomes, (c) greater understanding of the role of child characteristics, family history, and other contextual factors, including effects on children due to interrelations between marital conflict and parenting, and (d) advances in the conceptualization of children's outcomes, including that effects may be more productively viewed as dynamic processes of functioning rather than simply clinical diagnoses. Understanding of the impact of marital conflict on children as a function of time-related processes remains a gap in a process-oriented conceptualization of effects. Based on this review, a revised model for a process-oriented approach on the effects of marital discord on children is proposed and suggestions are made for future research directions.

  14. [Research advances in secondary development of Chinese patent medicines based on quality by design concept].

    Science.gov (United States)

    Gong, Xing-Chu; Chen, Teng; Qu, Hai-Bin

    2017-03-01

    Quality by design (QbD) concept is an advanced pharmaceutical quality control concept. The application of QbD concept in the research and development of pharmaceutical processes of traditional Chinese medicines (TCM) mainly contains five parts, including the definition of critical processes and their evaluation criteria, the determination of critical process parameters and critical material attributes, the establishment of quantitative models, the development of design space, as well as the application and continuous improvement of control strategy. In this work, recent research advances in QbD concept implementation methods in the secondary development of Chinese patent medicines were reviewed, and five promising fields of the implementation of QbD concept were pointed out, including the research and development of TCM new drugs and Chinese medicine granules for formulation, modeling of pharmaceutical processes, development of control strategy based on industrial big data, strengthening the research of process amplification rules, and the development of new pharmaceutical equipment.. Copyright© by the Chinese Pharmaceutical Association.

  15. Saudi Arabia: A future regional hub for advanced education, research, science and technology.

    Science.gov (United States)

    Meo, Sultan Ayoub

    2015-10-01

    Saudi Arabia is the largest country of the Arabian Peninsula, blessed with significant natural resources, including oil, gas and minerals. Saudi Arabia has recognised the importance of education in social and economic transformation, and has established a large number of universities, research and advanced technical institutes which have broken the metropolitan boundaries and have been extended to the far-flung areas of the country. There are 68 universities and degree-awarding institutes. The educational budget reached its highest-ever level of $56.56 billion for the year 2014. About 124,000 Saudi students are pursuing higher education in about 500 universities around the world. Saudi Arabia produced 177826 research papers in Institute for Scientific Information (ISI) database and in the year 2014 alone, 26168 research papers were published in indexed science journals with a rising h-index of 144. The country is turning into a regional hub for advanced education, research, science and technology while swiftly shifting from an oil-based to a knowledge-based economy.

  16. JSC Advanced Curation: Research and Development for Current Collections and Future Sample Return Mission Demands

    Science.gov (United States)

    Fries, M. D.; Allen, C. C.; Calaway, M. J.; Evans, C. A.; Stansbery, E. K.

    2015-01-01

    Curation of NASA's astromaterials sample collections is a demanding and evolving activity that supports valuable science from NASA missions for generations, long after the samples are returned to Earth. For example, NASA continues to loan hundreds of Apollo program samples to investigators every year and those samples are often analyzed using instruments that did not exist at the time of the Apollo missions themselves. The samples are curated in a manner that minimizes overall contamination, enabling clean, new high-sensitivity measurements and new science results over 40 years after their return to Earth. As our exploration of the Solar System progresses, upcoming and future NASA sample return missions will return new samples with stringent contamination control, sample environmental control, and Planetary Protection requirements. Therefore, an essential element of a healthy astromaterials curation program is a research and development (R&D) effort that characterizes and employs new technologies to maintain current collections and enable new missions - an Advanced Curation effort. JSC's Astromaterials Acquisition & Curation Office is continually performing Advanced Curation research, identifying and defining knowledge gaps about research, development, and validation/verification topics that are critical to support current and future NASA astromaterials sample collections. The following are highlighted knowledge gaps and research opportunities.

  17. The promise of mixed-methods for advancing latino health research.

    Science.gov (United States)

    Apesoa-Varano, Ester Carolina; Hinton, Ladson

    2013-09-01

    Mixed-methods research in the social sciences has been conducted for quite some time. More recently, mixed-methods have become popular in health research, with the National Institutes of Health leading the impetus to fund studies that implement such an approach. The public health issues facing us today are great and they range from policy and other macro-level issues, to systems level problems to individuals' health behaviors. For Latinos, who are projected to become the largest minority group bearing a great deal of the burden of social inequality in the U.S., it is important to understand the deeply-rooted nature of these health disparities in order to close the gap in health outcomes. Mixed-methodology thus holds promise for advancing research on Latino heath by tackling health disparities from a variety of standpoints and approaches. The aim of this manuscript is to provide two examples of mixed methods research, each of which addresses a health topic of considerable importance to older Latinos and their families. These two examples will illustrate a) the complementary use of qualitative and quantitative methods to advance health of older Latinos in an area that is important from a public health perspective, and b) the "translation" of findings from observational studies (informed by social science and medicine) to the development and testing of interventions.

  18. Contributions to advances in blend pellet products (BPP) research on molecular structure and molecular nutrition interaction by advanced synchrotron and globar molecular (Micro)spectroscopy.

    Science.gov (United States)

    Guevara-Oquendo, Víctor H; Zhang, Huihua; Yu, Peiqiang

    2018-04-13

    To date, advanced synchrotron-based and globar-sourced techniques are almost unknown to food and feed scientists. There has been little application of these advanced techniques to study blend pellet products at a molecular level. This article aims to provide recent research on advanced synchrotron and globar vibrational molecular spectroscopy contributions to advances in blend pellet products research on molecular structure and molecular nutrition interaction. How processing induced molecular structure changes in relation to nutrient availability and utilization of the blend pellet products. The study reviews Utilization of co-product components for blend pellet product in North America; Utilization and benefits of inclusion of pulse screenings; Utilization of additives in blend pellet products; Application of pellet processing in blend pellet products; Conventional evaluation techniques and methods for blend pellet products. The study focus on recent applications of cutting-edge vibrational molecular spectroscopy for molecular structure and molecular structure association with nutrient utilization in blend pellet products. The information described in this article gives better insight on how advanced molecular (micro)spectroscopy contributions to advances in blend pellet products research on molecular structure and molecular nutrition interaction.

  19. NHERI: Advancing the Research Infrastructure of the Multi-Hazard Community

    Science.gov (United States)

    Blain, C. A.; Ramirez, J. A.; Bobet, A.; Browning, J.; Edge, B.; Holmes, W.; Johnson, D.; Robertson, I.; Smith, T.; Zuo, D.

    2017-12-01

    The Natural Hazards Engineering Research Infrastructure (NHERI), supported by the National Science Foundation (NSF), is a distributed, multi-user national facility that provides the natural hazards research community with access to an advanced research infrastructure. Components of NHERI are comprised of a Network Coordination Office (NCO), a cloud-based cyberinfrastructure (DesignSafe-CI), a computational modeling and simulation center (SimCenter), and eight Experimental Facilities (EFs), including a post-disaster, rapid response research facility (RAPID). Utimately NHERI enables researchers to explore and test ground-breaking concepts to protect homes, businesses and infrastructure lifelines from earthquakes, windstorms, tsunamis, and surge enabling innovations to help prevent natural hazards from becoming societal disasters. When coupled with education and community outreach, NHERI will facilitate research and educational advances that contribute knowledge and innovation toward improving the resiliency of the nation's civil infrastructure to withstand natural hazards. The unique capabilities and coordinating activities over Year 1 between NHERI's DesignSafe-CI, the SimCenter, and individual EFs will be presented. Basic descriptions of each component are also found at https://www.designsafe-ci.org/facilities/. Additionally to be discussed are the various roles of the NCO in leading development of a 5-year multi-hazard science plan, coordinating facility scheduling and fostering the sharing of technical knowledge and best practices, leading education and outreach programs such as the recent Summer Institute and multi-facility REU program, ensuring a platform for technology transfer to practicing engineers, and developing strategic national and international partnerships to support a diverse multi-hazard research and user community.

  20. Proceedings of the NATO Advanced Research Workshop on Countering Nuclear and Radiological Terrorism

    International Nuclear Information System (INIS)

    Apikyan, S.; Diamond, D.

    2006-01-01

    The objective of this workshop was to identify connections between technology needs and the underlying science and technology, and to establish research strategies that will advanced our ability to counter this form of terrorism. The objectives were met by bringing together international experts familiar with the relevant technologies and policies at a four-day workshop that was held at the Regional Advanced Science and Technology Center (ASTEC), Yerevan, Armenia during October 2005. The many topics covered included: radiation detector development, risk assessment and decision making, decontamination techniques, structural materials resistance to conventional explosives, vulnerability and physical protection of nuclear facilities, security of radiation sources, response to radiological dispersion devices, relevant international and national laws, and non-proliferation

  1. A Distributed Simulation Facility to Support Human Factors Research in Advanced Air Transportation Technology

    Science.gov (United States)

    Amonlirdviman, Keith; Farley, Todd C.; Hansman, R. John, Jr.; Ladik, John F.; Sherer, Dana Z.

    1998-01-01

    A distributed real-time simulation of the civil air traffic environment developed to support human factors research in advanced air transportation technology is presented. The distributed environment is based on a custom simulation architecture designed for simplicity and flexibility in human experiments. Standard Internet protocols are used to create the distributed environment, linking all advanced cockpit simulator, all Air Traffic Control simulator, and a pseudo-aircraft control and simulation management station. The pseudo-aircraft control station also functions as a scenario design tool for coordinating human factors experiments. This station incorporates a pseudo-pilot interface designed to reduce workload for human operators piloting multiple aircraft simultaneously in real time. The application of this distributed simulation facility to support a study of the effect of shared information (via air-ground datalink) on pilot/controller shared situation awareness and re-route negotiation is also presented.

  2. NATO Advanced Research Workshop on Frontiers in Polymerization Catalysis and Polymer Synthesis

    CERN Document Server

    Guyot, A

    1987-01-01

    Due to their specific properties, polymers with well-defined structures have been receiving increasing attention over the last several years. Owing to the wide variability of their properties, these specialty polymers have been used in various areas from biomedical engineering to electronics or energy applications. The synthesis of such polymers necessi­ tates the use of new methods of polymerization which derived from an insight into the mechanism of polymerization reactions. A NATO Advanced Research Workshop on "Frontiers in Polymerization Catalysis and Polymer Synthesis" was held in BANDOl (FRANCE) in February 1987. Its aim was to assess the new polymerization methods, as well as the latest advances in the mechanisms of conventional polymerization reactions together with their applications to the synthesis of new macromolecular structures. The financial support from the NATO Scientific Affairs Division which covered the "lecturers' accomodation and travel expenses as well as the organization charges of th...

  3. Proceedings of the Twenty-First Water Reactor Safety Information Meeting: Volume 1, Plenary session; Advanced reactor research; advanced control system technology; advanced instrumentation and control hardware; human factors research; probabilistic risk assessment topics; thermal hydraulics; thermal hydraulic research for advanced passive LWRs

    International Nuclear Information System (INIS)

    Monteleone, S.

    1994-04-01

    This three-volume report contains 90 papers out of the 102 that were presented at the Twenty-First Water Reactor Safety Information Meeting held at the Bethesda Marriott Hotel, Bethesda, Maryland, during the week of October 25--27, 1993. The papers are printed in the order of their presentation in each session and describe progress and results of programs in nuclear safety research conducted in this country and abroad. Foreign participation in the meeting included papers presented by researchers from France, Germany, Japan, Russia, Switzerland, Taiwan, and United Kingdom. The titles of the papers and the names of the authors have been updated and may differ from those that appeared in the final program of the meeting. Individual papers have been cataloged separately. This document, Volume 1 covers the following topics: Advanced Reactor Research; Advanced Instrumentation and Control Hardware; Advanced Control System Technology; Human Factors Research; Probabilistic Risk Assessment Topics; Thermal Hydraulics; and Thermal Hydraulic Research for Advanced Passive Light Water Reactors

  4. Proceedings of the Twenty-First Water Reactor Safety Information Meeting: Volume 1, Plenary session; Advanced reactor research; advanced control system technology; advanced instrumentation and control hardware; human factors research; probabilistic risk assessment topics; thermal hydraulics; thermal hydraulic research for advanced passive LWRs

    Energy Technology Data Exchange (ETDEWEB)

    Monteleone, S. [Brookhaven National Lab., Upton, NY (United States)] [comp.

    1994-04-01

    This three-volume report contains 90 papers out of the 102 that were presented at the Twenty-First Water Reactor Safety Information Meeting held at the Bethesda Marriott Hotel, Bethesda, Maryland, during the week of October 25--27, 1993. The papers are printed in the order of their presentation in each session and describe progress and results of programs in nuclear safety research conducted in this country and abroad. Foreign participation in the meeting included papers presented by researchers from France, Germany, Japan, Russia, Switzerland, Taiwan, and United Kingdom. The titles of the papers and the names of the authors have been updated and may differ from those that appeared in the final program of the meeting. Individual papers have been cataloged separately. This document, Volume 1 covers the following topics: Advanced Reactor Research; Advanced Instrumentation and Control Hardware; Advanced Control System Technology; Human Factors Research; Probabilistic Risk Assessment Topics; Thermal Hydraulics; and Thermal Hydraulic Research for Advanced Passive Light Water Reactors.

  5. Special issue on the "Consortium for Advanced Simulation of Light Water Reactors Research and Development Progress"

    Science.gov (United States)

    Turinsky, Paul J.; Martin, William R.

    2017-04-01

    In this special issue of the Journal of Computational Physics, the research and development completed at the time of manuscript submission by the Consortium for Advanced Simulation of Light Water Reactors (CASL) is presented. CASL is the first of several Energy Innovation Hubs that have been created by the Department of Energy. The Hubs are modeled after the strong scientific management characteristics of the Manhattan Project and AT&T Bell Laboratories, and function as integrated research centers that combine basic and applied research with engineering to accelerate scientific discovery that addresses critical energy issues. Lifetime of a Hub is expected to be five or ten years depending upon performance, with CASL being granted a ten year lifetime.

  6. Advances in research on and diagnosis and treatment of achondroplasia in China

    Science.gov (United States)

    Wang, Yao; Liu, Zeying; Liu, Zhenxing; Zhao, Heng; Zhou, Xiaoyan; Cui, Yazhou; Han, Jinxiang

    2013-01-01

    Summary Achondroplasia is a rare autosomal dominant genetic disease. Research on achondroplasia in China, however, has received little emphasis. Around 80–90% of cases of neonatal achondroplasia result from mutations in fibroblast growth factor receptor 3 (FGFR3) according to polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP). Recently, genetic research on achondroplasia in China made a major breakthrough by revealing two novel mutations located on the FGFR3 gene, thus helping to complete the pathological molecular map of achondroplasia. There are still, however, unknown aspects of the diagnosis and treatment of achondroplasia. This review will summarize advances in research on and the clinical diagnosis and treatment of achondroplasia in China. PMID:25343101

  7. Insights and advances in multidisciplinary critical care: a review of recent research.

    Science.gov (United States)

    Blot, Stijn; Afonso, Elsa; Labeau, Sonia

    2014-01-01

    The intensive care unit is a work environment where superior dedication is pivotal to optimize patients' outcomes. As this demanding commitment is multidisciplinary in nature, it requires special qualities of health care workers and organizations. Thus research in the field covers a broad spectrum of activities necessary to deliver cutting-edge care. However, given the abundance of research articles and education activities available, it is difficult for modern critical care clinicians to keep up with the latest progress and innovations in the field. This article broadly summarizes new developments in multidisciplinary intensive care, providing elementary information about advanced insights in the field by briefly describing selected articles bundled in specific topics. Issues considered include cardiovascular care, monitoring, mechanical ventilation, infection and sepsis, nutrition, education, patient safety, pain assessment and control, delirium, mental health, ethics, and outcomes research.

  8. The advanced neutron source - A world-class research reactor facility

    International Nuclear Information System (INIS)

    Thompson, P.B.; Meek, W.E.

    1993-01-01

    The advanced neutron source (ANS) is a new facility being designed at the Oak Ridge National Laboratory that is based on a heavy-water-moderated reactor and extensive experiment and user-support facilities. The primary purpose of the ANS is to provide world-class facilities for neutron scattering research, isotope production, and materials irradiation in the United States. The neutrons provided by the reactor will be thermalized to produce sources of hot, thermal, cold, very cold, and ultracold neutrons usable at the experiment stations. Beams of cold neutrons will be directed into a large guide hall using neutron guide technology, greatly enhancing the number of research stations possible in the project. Fundamental and nuclear physics, materials analysis, and other research pro- grams will share the neutron beam facilities. Sufficient laboratory and office space will be provided to create an effective user-oriented environment

  9. [Advances in the research of application of collagen in three-dimensional bioprinting].

    Science.gov (United States)

    Li, H H; Luo, P F; Sheng, J J; Liu, G C; Zhu, S H

    2016-10-20

    As a new industrial technology with characteristics of high precision and accuracy, the application of three-dimensional bioprinting technology is increasingly wide in the field of medical research. Collagen is one of the most common ingredients in tissue, and it has good biological material properties. There are many reports of using collagen as main composition of " ink" of three-dimensional bioprinting technology. However, the applied collagen is mainly from heterogeneous sources, which may cause some problems in application. Recombinant human source collagen can be obtained from microorganism fermentation by transgenic technology, but more research should be done to confirm its property. This article reviews the advances in the research of collagen and its biological application in three-dimensional bioprinting.

  10. Review of research on advanced computational science in FY2010-2014

    International Nuclear Information System (INIS)

    2016-03-01

    Research on advanced computational science for nuclear applications, based on 'the plan for meeting the mid-term goal of the Japan Atomic Energy Agency', has been performed at Center for Computational Science and e-Systems (CCSE), Japan Atomic Energy Agency. CCSE established the committee consisting outside experts and authorities which does research evaluation and advices for the assistance of the research and development. This report summarizes the followings. (1) Results of the R and D performed at CCSE in the period of the midterm plan (April 1st, 2010 - March 31st, 2015) (2) Results of the evaluation on the R and D by the committee in the period of the midterm plan (April 1st, 2010 - March 31st, 2015). (author)

  11. A preliminary exploration of the advanced molecular bio-sciences research center

    International Nuclear Information System (INIS)

    Yanai, Takanori; Yamada, Yutaka; Tanaka, Kimio; Yamagami, Mutsumi; Sota, Masahiro; Takemura, Tatsuo; Koyama, Kenji; Sato, Fumiaki

    2001-01-01

    Low dose and low dose rate radiation effects on lifespan, pathological changes, hemopoiesis and cytokine production in mice have been investigated in our laboratory. In the intermediate period of the investigation, an expert committee on radiation biology was organized. The purposes of the committee were to assess previous studies and advise on a future research plan for the Advanced Molecular Bio-Sciences Research Center (AMBIC). The committee emphasized the necessity of molecular research in radiation biology, and proposed the following five subjects: 1) molecular carcinogenesis by low dose radiation; 2) radiation effects on the immune and hemopoietic systems; 3) molecular mechanisms of hereditary effect; 4) noncancer diseases of low dose radiation, and 5) cellular mechanisms by low dose radiation. (author)

  12. Office of River Protection Advanced Low-Activity Waste Glass Research and Development Plan

    Energy Technology Data Exchange (ETDEWEB)

    Peeler, David K. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kim, Dong-Sang [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Vienna, John D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Schweiger, Michael J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Piepel, Gregory F. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-11-01

    The U.S. Department of Energy Office of River Protection (ORP) has initiated and leads an integrated Advanced Waste Glass (AWG) program to increase the loading of Hanford tank wastes in glass while meeting melter lifetime expectancies and process, regulatory, and product performance requirements. The integrated ORP program is focused on providing a technical, science-based foundation for making key decisions regarding the successful operation of the Hanford Tank Waste Treatment and Immobilization Plant (WTP) facilities in the context of an optimized River Protection Project (RPP) flowsheet. The fundamental data stemming from this program will support development of advanced glass formulations, key product performance and process control models, and tactical processing strategies to ensure safe and successful operations for both the low-activity waste (LAW) and high-level waste vitrification facilities. These activities will be conducted with the objective of improving the overall RPP mission by enhancing flexibility and reducing cost and schedule. The purpose of this advanced LAW glass research and development plan is to identify the near-term, mid-term, and longer-term research and development activities required to develop and validate advanced LAW glasses, property-composition models and their uncertainties, and an advanced glass algorithm to support WTP facility operations, including both Direct Feed LAW and full pretreatment flowsheets. Data are needed to develop, validate, and implement 1) new glass property-composition models and 2) a new glass formulation algorithm. Hence, this plan integrates specific studies associated with increasing the Na2O and SO3/halide concentrations in glass, because these components will ultimately dictate waste loadings for LAW vitrification. Of equal importance is the development of an efficient and economic strategy for 99Tc management. Specific and detailed studies are being implemented to understand the fate of Tc throughout

  13. Misrepresenting random sampling? A systematic review of research papers in the Journal of Advanced Nursing.

    Science.gov (United States)

    Williamson, Graham R

    2003-11-01

    This paper discusses the theoretical limitations of the use of random sampling and probability theory in the production of a significance level (or P-value) in nursing research. Potential alternatives, in the form of randomization tests, are proposed. Research papers in nursing, medicine and psychology frequently misrepresent their statistical findings, as the P-values reported assume random sampling. In this systematic review of studies published between January 1995 and June 2002 in the Journal of Advanced Nursing, 89 (68%) studies broke this assumption because they used convenience samples or entire populations. As a result, some of the findings may be questionable. The key ideas of random sampling and probability theory for statistical testing (for generating a P-value) are outlined. The result of a systematic review of research papers published in the Journal of Advanced Nursing is then presented, showing how frequently random sampling appears to have been misrepresented. Useful alternative techniques that might overcome these limitations are then discussed. REVIEW LIMITATIONS: This review is limited in scope because it is applied to one journal, and so the findings cannot be generalized to other nursing journals or to nursing research in general. However, it is possible that other nursing journals are also publishing research articles based on the misrepresentation of random sampling. The review is also limited because in several of the articles the sampling method was not completely clearly stated, and in this circumstance a judgment has been made as to the sampling method employed, based on the indications given by author(s). Quantitative researchers in nursing should be very careful that the statistical techniques they use are appropriate for the design and sampling methods of their studies. If the techniques they employ are not appropriate, they run the risk of misinterpreting findings by using inappropriate, unrepresentative and biased samples.

  14. Community cyberinfrastructure for Advanced Microbial Ecology Research and Analysis: the CAMERA resource.

    Science.gov (United States)

    Sun, Shulei; Chen, Jing; Li, Weizhong; Altintas, Ilkay; Lin, Abel; Peltier, Steve; Stocks, Karen; Allen, Eric E; Ellisman, Mark; Grethe, Jeffrey; Wooley, John

    2011-01-01

    The Community Cyberinfrastructure for Advanced Microbial Ecology Research and Analysis (CAMERA, http://camera.calit2.net/) is a database and associated computational infrastructure that provides a single system for depositing, locating, analyzing, visualizing and sharing data about microbial biology through an advanced web-based analysis portal. CAMERA collects and links metadata relevant to environmental metagenome data sets with annotation in a semantically-aware environment allowing users to write expressive semantic queries against the database. To meet the needs of the research community, users are able to query metadata categories such as habitat, sample type, time, location and other environmental physicochemical parameters. CAMERA is compliant with the standards promulgated by the Genomic Standards Consortium (GSC), and sustains a role within the GSC in extending standards for content and format of the metagenomic data and metadata and its submission to the CAMERA repository. To ensure wide, ready access to data and annotation, CAMERA also provides data submission tools to allow researchers to share and forward data to other metagenomics sites and community data archives such as GenBank. It has multiple interfaces for easy submission of large or complex data sets, and supports pre-registration of samples for sequencing. CAMERA integrates a growing list of tools and viewers for querying, analyzing, annotating and comparing metagenome and genome data.

  15. 25 Years of DECOVALEX - Research Advances and Lessons Learned from an International Model Comparison Initiative

    Science.gov (United States)

    Birkholzer, J. T.

    2017-12-01

    This presentation provides an overview of an international research and model comparison collaboration (DECOVALEX) for advancing the understanding and modeling of coupled thermo-hydro-mechanical-chemical (THMC) processes in geological systems. Prediction of these coupled effects is an essential part of the performance and safety assessment of geologic disposal systems for radioactive waste and spent nuclear fuel, and is also relevant for a range of other sub-surface engineering activities. DECOVALEX research activities have been supported by a large number of radioactive-waste-management organizations and regulatory authorities. Research teams from more than a dozen international partner organizations have participated in the comparative modeling evaluation of complex field and laboratory experiments in the UK, Switzerland, Japan, France and Sweden. Together, these tasks (1) have addressed a wide range of relevant issues related to engineered and natural system behavior in argillaceous, crystalline and other host rocks, (2) have yielded in-depth knowledge of coupled THM and THMC processes associated with nuclear waste repositories and wider geo-engineering applications, and (3) have advanced the capability, as well as demonstrated the suitability, of numerical simulation models for quantitative analysis.

  16. Development of a Fissile Materials Irradiation Capability for Advanced Fuel Testing at the MIT Research Reactor

    International Nuclear Information System (INIS)

    Hu Linwen; Bernard, John A.; Hejzlar, Pavel; Kohse, Gordon

    2005-01-01

    A fissile materials irradiation capability has been developed at the Massachusetts Institute of Technology (MIT) Research Reactor (MITR) to support nuclear engineering studies in the area of advanced fuels. The focus of the expected research is to investigate the basic properties of advanced nuclear fuels using small aggregates of fissile material. As such, this program is intended to complement the ongoing fuel evaluation programs at test reactors. Candidates for study at the MITR include vibration-packed annular fuel for light water reactors and microparticle fuels for high-temperature gas reactors. Technical considerations that pertain to the design of the MITR facility are enumerated including those specified by 10 CFR 50 concerning the definition of a research reactor and those contained in a separate license amendment that was issued by the U.S. Nuclear Regulatory Commission to MIT for these types of experiments. The former includes limits on the cross-sectional area of the experiment, the physical form of the irradiated material, and the removal of heat. The latter addresses experiment reactivity worth, thermal-hydraulic considerations, avoidance of fission product release, and experiment specific temperature scrams

  17. Needs assessment for developing a program to help train advanced-practice pharmacists for research.

    Science.gov (United States)

    Bulkley, Christina F; Miller, Michael J; Bush, Colleen G; Nussbaum, Barbara B; Draugalis, JoLaine R

    2017-12-01

    Results of a needs assessment to determine priority topics and preferred formats for research training in pharmacy residency programs are reported. For pharmacists seeking advanced-practice positions in academia, the ability to conduct practice-based research is expected. Pharmacy residency programs are a primary recruitment source for these positions, but research training varies by residency site and available expertise. To help define the optimal content and format of resident research training, ASHP and the ASHP Research and Education Foundation conducted a needs assessment targeting postgraduate year 1 (PGY1) pharmacy residency directors (RPDs). The response rate was 36.5% (271 of 743 invitees); the information obtained was used to guide development of a Web-based training series. Only 12% of the RPDs who participated in the survey indicated that currently available research training resources within their residency programs were sufficient. Sixty-seven percent of surveyed RPDs agreed that a Web-based training program would be a useful resource, and 81% agreed that the target audience should be pharmacy residents. Training topics of greatest interest to RPDs included (1) components of a resident research plan, (2) identifying research questions, (3) study design and sample selection, (4) project management, (5) data acquisition, cleaning, management, and analysis, and (6) presenting and publishing project results. This needs assessment clearly identified opportunities for improving the infrastructure and content of PGY1 residency research training. At a minimum, training programs should focus on practice-based research concepts using readily accessible health-system data systems and provide universal accessibility and sufficient flexibility to allow residency programs to integrate the training in a manner that works best for the program. Copyright © 2017 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

  18. Advancing Research and Practice: The Revised APA Division 30 Definition of Hypnosis.

    Science.gov (United States)

    Elkins, Gary R; Barabasz, Arreed F; Council, James R; Spiegel, David

    2015-04-01

    This article describes the history, rationale, and guidelines for developing a new definition of hypnosis by the Society of Psychological Hypnosis, Division 30 of the American Psychological Association. The definition was developed with the aim of being concise, being heuristic, and allowing for alternative theories of the mechanisms (to be determined in empirical scientific study). The definition of hypnosis is presented as well as definitions of the following related terms: hypnotic induction, hypnotizability, and hypnotherapy. The implications for advancing research and practice are discussed. The definitions are presented within the article.

  19. The Advanced Light Source: A new tool for research in atomic and molecular physics

    International Nuclear Information System (INIS)

    Schlachter, F.; Robinson, A.

    1991-04-01

    The Advanced Light Source at the Lawrence Berkeley Laboratory will be the world's brightest synchrotron radiation source in the extreme ultraviolet and soft x-ray regions of the spectrum when it begins operation in 1993. It will be available as a national user facility to researchers in a broad range of disciplines, including materials science, atomic and molecular physics, chemistry, biology, imaging, and technology. The high brightness of the ALS will be particularly well suited to high-resolution studies of tenuous targets, such as excited atoms, ions, and clusters. 13 figs., 4 tabs

  20. Research advances in the treatment of Alzheimer's disease with polysaccharides from traditional Chinese medicine.

    Science.gov (United States)

    Liu, Qin; Wang, Shun-Chun; Ding, Kan

    2017-09-01

    Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the loss of patients' memory and their cognitive abilities and the mechanism is not completely clear. Although a variety of drugs have been approved for the AD treatment, substances which can prevent and cure AD are still in great need. The effect of polysaccharides from traditional Chinese medicine (TCM) on anti-AD has gained great progress and attained more and more attention in recent years. In this review, research advances in TCM-polysaccharides on AD made in this decade are summarized. Copyright © 2017 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.