WorldWideScience

Sample records for adolescence sequelas endocrinas

  1. Endocrine sequelae after radiotherapy in childhood and adolescence; Sequelas endocrinas da radioterapia no tratamento do cancer na infancia e adolescencia

    Energy Technology Data Exchange (ETDEWEB)

    Couto-Silva, Ana Claudia; Adan, Luis Fernando [Universidade Federal da Bahia, Salvador, BA (Brazil); Brauner, Raja [Paris-5 Univ. (France)

    2005-10-15

    Radiotherapy may result in endocrine abnormalities, osteoporosis, obesity and neurological sequelae in patients treated for cancer. In the hypothalamo-pituitary area, GH deficiency is the most frequent complication. The frequency, delay of appearance and severity of GH deficiency depend most on the dose delivered during cranial irradiation but variables as age at treatment and fractionation schedule may play an important role as well. Other hypothalamo-pituitary dysfunctions are also dose-dependent. Low dose cranial irradiation may induce precocious or early puberty, while high doses are related to gonadotropin deficiency. Endocrine complications due to extracranial irradiation such as gonadal or thyroid abnormalities are described. In spite of normal GH secretion, linear growth may be impaired by bone lesions secondary to craniospinal or total body irradiation. Results on final height have been optimized by better indicators of GH therapy associated with adequate treatment of early or precocious puberty. The purpose of this review is to explore the late endocrine sequelae of radiotherapy. (author)

  2. Adult Sequela of Adolescent Heavy Drinking among Mexican Americans.

    Science.gov (United States)

    Vega, William A.; Alderete, Ethel; Kolody, Bohdan; Aguilar-Gaxiola, Sergio

    2000-01-01

    Data from the Mexican American Prevalence and Services Survey were used to compare mental health and behavioral sequela of heavy drinking in adolescence among Mexican Americans aged 18-59. Adolescent heavy drinkers had higher lifetime mood or drug dependence disorders and higher rates of suicide attempts and behavior problems than abstainers or…

  3. Sequelae of closed craniocerebral trauma and the efficacy of piracetam in its treatment in adolescents.

    Science.gov (United States)

    Zavadenko, N N; Guzilova, L S

    2009-05-01

    The efficacy of piracetam in treating the sequelae of moderate and severe closed craniocerebral trauma (CCT) in adolescents was evaluated in studies of 42 patients aged 12-18 years who had suffered CCT 1.5-5 years prior to the study. Adolescents of the experimental group (20 individuals) received piracetam (Nootropil) at doses of 40-50 mg/kg (daily daily 1600-2400 mg) for one month; patients of group 2 (22 individuals) served as controls. Piracetam was found to have positive therapeutic effects on impairments to higher mental (memory, attention, executive) and motor (coordination) functions and on measures of the speeds of cognitive and motor operations.

  4. Attachment Theory as a Framework for Understanding Sequelae of Severe Adolescent Psychopathology: An 11-Year Follow-Up Study.

    Science.gov (United States)

    Allen, Joseph P.; And Others

    1996-01-01

    Examined long-term sequelae of severe adolescent psychopathology from the perspective of adult attachment theory. Compared 66 upper-middle-class adolescents who were psychiatrically hospitalized at age 14 for problems other than thought or organic disorders, to 76 socio-demographically similar high school students. When reviewed at age 25,…

  5. Perspectivas en disrupción endocrina

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    Olea N.; Fernández M.F.; Araque P.; Olea-Serrano F.

    2002-01-01

    La descripción de alteraciones en la función reproductora de algunas especies de animales salvajes, junto a la demostración de la exposición humana y animal a sustancias químicas con actividad hormonal -agonista y antagonista- generó, hace dos décadas, lo que se conoce hoy día como hipótesis de disrupción endocrina. Se trata de un problema emergente de salud medioambiental que ha cuestionado algunos de los paradigmas en que se fundamenta el control y la regulación de uso de los compuestos quí...

  6. Neoplasia endocrina múltiple tipo-2b

    OpenAIRE

    Lastra, Guido; de Franco, Roberto; Rueda P., Pedro Nel; Pradilla S., Lina P.; Paz C., Óscar

    2014-01-01

    La neoplasia endocrina multiple tipo 2 comprendetres sindromes : la neoplasia endocrina múltiple2A con predisposición genética para desarrollarcarcinoma medular del tiroides,feocromocitoma e hiperplasia primaria deparatiroides. La neoplasia endocrina múltiple 2B,desorden autosómico dominante con feocromocitomay carcinoma medular del tiroides quegeneralmente se presenta a una edad más tempranay es más agresivo que la de tipo 2A, porlo que su diagnóstico precoz es crítico; estospacientes, que t...

  7. Management of mental health disorders and central nervous system sequelae in HIV-positive children and adolescents

    Directory of Open Access Journals (Sweden)

    R Nassen

    2014-09-01

    Full Text Available HIV-positive children and adolescents are at increased risk of both central nervous system (CNS sequelae and mental disorders owing to a number of factors, including the impact of HIV infection on the brain, social determinants of health (e.g. poverty and orphanhood and psychosocial stressors related to living with HIV. Every effort should be made to identify perinatally HIV-infected children and initiate them on antiretroviral therapy early in life. HIV clinicians should ideally screen for mental health and neurocognitive problems, as part of the routine monitoring of children attending antiretroviral clinics. This guideline is intended as a reference tool for HIV clinicians to support the early identification, screening and management of mental health disorders and/or CNS impairment in children and adolescents. This guideline covers mental disorders (section 1 and HIV-associated neurocognitive disorders (section 2 among children and adolescents.  

  8. Perspectivas en disrupción endocrina

    Directory of Open Access Journals (Sweden)

    Olea N.

    2002-01-01

    Full Text Available La descripción de alteraciones en la función reproductora de algunas especies de animales salvajes, junto a la demostración de la exposición humana y animal a sustancias químicas con actividad hormonal -agonista y antagonista- generó, hace dos décadas, lo que se conoce hoy día como hipótesis de disrupción endocrina. Se trata de un problema emergente de salud medioambiental que ha cuestionado algunos de los paradigmas en que se fundamenta el control y la regulación de uso de los compuestos químicos. La necesidad de incluir en los tests toxicológicos habituales nuevos objetivos de investigación, que se refieren específicamente al desarrollo y crecimiento de las especies y a la homeostasis y funcionalidad de los sistemas hormonales, ha venido a complicar tanto la evaluación de los nuevos compuestos químicos como la revaluación de los existentes. Sus repercusiones sobre la reglamentación y el comercio internacional no se han hecho esperar y a ambos lados del Atlántico se han diseñado y establecido sistemas de cribado de disruptores endocrinos y se han desarrollado programas de investigación con objeto de cualificar y cuantificar los efectos adversos sobre la salud humana y animal y poder actuar con medidas de prevención.

  9. The impact of a family-centered intervention on the ecology of adolescent antisocial behavior: modeling developmental sequelae and trajectories during adolescence.

    Science.gov (United States)

    Van Ryzin, Mark J; Dishion, Thomas J

    2012-08-01

    This study used an experimental, longitudinal field trial involving random assignment to the Family Check-Up (FCU) to explore the social ecology of adolescent antisocial behavior. A sample of 998 youths and their families was followed from early to late adolescence (age 12 to 18-19). In the intervention condition, 115 families (23%) elected to receive the FCU. In general, random assignment to the FCU in middle school was associated with reductions in late adolescence antisocial behavior (age 18-19). Variable-centered analyses revealed that the effects were mediated by reductions in family conflict from early to middle adolescence (age 12-15). The link between family conflict and antisocial behavior in turn was mediated by association with deviant peers at age 17; parental monitoring at age 17 was also influential but did not attain the status of a mediator. Person-oriented analyses suggested that the FCU was associated with declining trajectories of family conflict and rising trajectories of parental monitoring but was not associated with trajectories of deviant peer association. A dual-trajectory analysis indicated that the pathways to adolescent antisocial behavior were myriad and varied, suggesting new directions for developmental and intervention research.

  10. Tejido adiposo como glándula endocrina. Implicaciones fisiopatológicas.

    OpenAIRE

    Dayamí García Torres; Maricel F. Castellanos González; Raúl Cedeño Morales; Mikhail Benet Rodríguez; Illovis Ramírez Arteaga

    2011-01-01

    El tejido adiposo se considera en la actualidad como un órgano con importante función endocrina; distinguiéndose dos tipos: el pardo y el blanco. El tejido adiposo es capaz de secretar diversas sustancias conocidas como adipocinas que se encuentran implicadas en la regulación del peso corporal, en el sistema inmune, en la función vascular y en la sensibilidad insulínica. En la obesidad, principalmente visceral, se encuentran aumentadas las adipocinas proinflamatorias. Estas se asocia...

  11. Tejido adiposo como glándula endocrina. Implicaciones fisiopatológicas.

    OpenAIRE

    Dayamí García Torres; Maricel F. Castellanos González; Raúl Cedeño Morales; Mikhail Benet Rodríguez; Illovis Ramírez Arteaga

    2011-01-01

    El tejido adiposo se considera en la actualidad como un órgano con importante función endocrina; distinguiéndose dos tipos: el pardo y el blanco. El tejido adiposo es capaz de secretar diversas sustancias conocidas como adipocinas que se encuentran implicadas en la regulación del peso corporal, en el sistema inmune, en la función vascular y en la sensibilidad insulínica. En la obesidad, principalmente visceral, se encuentran aumentadas las adipocinas proinflamatorias. Estas se asocia...

  12. Perspectivas en disrupción endocrina Perspectives in endocrine disruption

    OpenAIRE

    Olea, N; M.F. Fernández; P. Araque; Olea-Serrano, F

    2002-01-01

    La descripción de alteraciones en la función reproductora de algunas especies de animales salvajes, junto a la demostración de la exposición humana y animal a sustancias químicas con actividad hormonal ­agonista y antagonista­ generó, hace dos décadas, lo que se conoce hoy día como hipótesis de disrupción endocrina. Se trata de un problema emergente de salud medioambiental que ha cuestionado algunos de los paradigmas en que se fundamenta el control y la regulación de uso de los compue...

  13. Tejido adiposo como glándula endocrina. Implicaciones fisiopatológicas.

    Directory of Open Access Journals (Sweden)

    Dayamí García Torres

    2011-08-01

    Full Text Available El tejido adiposo se considera en la actualidad como un órgano con importante función endocrina; distinguiéndose dos tipos: el pardo y el blanco. El tejido adiposo es capaz de secretar diversas sustancias conocidas como adipocinas que se encuentran implicadas en la regulación del peso corporal, en el sistema inmune, en la función vascular y en la sensibilidad insulínica. En la obesidad, principalmente visceral, se encuentran aumentadas las adipocinas proinflamatorias. Estas se asocian a la inflamación clínica y subclínica, a la insulinorresistencia, al estrés oxidativo y a la lesión endotelial; desarrollan un papel clave en el síndrome metabólico e incrementan el riesgo cardiometabólico. El objetivo de la presente revisión bibliográfica ha sido exponer las características morfofuncionales del tejido adiposo y los mecanismos que lo vinculan con la génesis de diversas enfermedades.

  14. German register for detection of late sequelae after radiotherapy for children and adolescents (RiSK): present status and first results

    Energy Technology Data Exchange (ETDEWEB)

    Boelling, T.; Schuck, A.; Willich, N. [Dept. of Radiotherapy of the Univ. Hospital Muenster (Germany); Pape, H. [Dept. of Radiotherapy of the Univ. Hospital Duesseldorf (Germany); Ruebe, C. [Dept. of Radiotherapy of the Univ. Saarland, Homburg/Saar (Germany); Meyer, F.M. [Dept. of Radiotherapy of the Clinic of Augsburg (Germany); Martini, C. [Dept. of Radiotherapy of the Univ. Hospitals Freiburg (Germany); Timmermann, B. [Paul Scherrer Inst., Villigen (Switzerland); Asadpour, B. [Dept. of Radiotherapy of the Univ. Hospital Aachen (Germany); Kortmann, R.D. [Dept. of Radiotherapy of the Univ. Hospital Leipzig (Germany); Beck, J.D.; Langer, T.; Paulides, M. [LESS Center, Univ. Children' s Hospital Erlangen (Germany)

    2007-12-15

    Undoubtedly, radiotherapy is an important treatment strategy for many malignancies in paediatric oncology. However, sufficient data about late side effects do not exist. There is a lack of information about radiation dose-effect relationships in view of late side effects in childhood and adolescence. Late effects after radiotherapy in childhood and adolescence have mainly been characterized retrospectively with small patient numbers. Many of these analyses are limited due to little information about organ dose levels and older radiation techniques in some cases. Therefore the German Group of Paediatric Radiation Oncology (APRO) established the 'Register for the evaluation of late side effects after radiation in childhood and adolescence (RiSK)'. Aim of this prospective multicentric register study is to evaluate irradiation dose effect relationships of organs and part of organs with respect to late effects. The feasibility of RiSK has already been shown and first results have recently been published. The characterization of late effects after cancer therapy in childhood is of rising interest. In Germany, several study groups like the 'Late Effects Surveillance System' (LESS) or the working group 'Quality of life' examine different aspects of late effects. In the United States of America, the 'Childhood Cancer Survivor Study' has been established to characterize retrospectively the health status of 5-year-survivors of childhood cancer. In these studies, more than 12,000 patients were evaluated by questionnaires regarding their health status. For radiotherapy, this study is not able to give detailed information about late side effects due to rare data about radiation doses and organ dose levels. To our knowledge, 'RiSK' is the only multicentric study that evaluates radiation associated side effects prospectively with detailed information about organ dose levels. (orig.)

  15. Adrenalectomía lumboscópica en un paciente con feocromocitoma y neoplasia endocrina múltiple tipo 2B

    OpenAIRE

    Guillermo Montoya-Martínez; Jorge Moreno-Palacios; Eduardo Serrano-Brambila

    2009-01-01

    La neoplasia endocrina múltiple tipo 2B es un padecimiento autosómico dominante, conlleva carcinoma medular de tiroides, feocromocitoma, ganglioneuromas en mucosas e intestino y habitus marfanoide. Se presenta el caso de un paciente de 35 años de edad con diagnóstico de neoplasia endocrina múltiple tipo 2B y feocromocitoma suprarrenal derecho, tratado con adrenalectomía lumboscópica. El diagnóstico del feocromocitoma incluye detección de catecolaminas en suero y orina, estudios de imagen como...

  16. Síndrome de neoplasia endocrina múltiple tipo 1 : diagnóstico genético y estudio clínico

    OpenAIRE

    Balsalobre Salmerón, María D.

    2008-01-01

    El concepto de neoplasia endocrina múltiple (MEN) engloba una serie de síndromes caracterizados por tener un origen genético y por la presentación en un mismo sujeto de afectación de una o más glándulas endocrinas por procesos tumorales. Estos procesos tumorales, se pueden encontrar en diferentes fases de evolución (hiperplasia pretumoral, carcinoma y metástasis). Dentro de los síndromes MEN se engloban dos grandes grupos denominados MEN tipo 1 y MEN tipo 2 (subdividido en 2A y 2B). El sí...

  17. Neoplasia endocrina múltiple tipo 2 en la Región de Murcia. Estudio clínico, genético y molecular

    OpenAIRE

    Portillo Ortega, Paloma

    2014-01-01

    Introducción La Neoplasia Endocrina Múltiple tipo 2 (MEN 2) se define como un conjunto de síndromes de herencia autosómica dominante, con alta penetrancia y expresividad variable, en el que mutaciones en el proto-oncogén RET dan origen a tres fenotipos diferentes: Neoplasia Endocrina Múltiple 2A (MEN2A), 2B (MEN2B) y Cáncer Medular de Tiroides Familiar (CMTF). Los distintos componentes clínicos de cada uno de ellos son: - Para MEN2A: Cáncer Medular de Tiroides (CMT), Feocromocitoma, ...

  18. Late sequelae of superficial irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Hood, I.C.; Young, J.E.

    1984-10-01

    Superficial irradiation results in well recognized late sequelae including not only sclerosis and atrophy of skin and subcutaneous tissue, but also the development of benign and malignant tumors of skin and adjacent structures. The long latency between irradiation and its late effects allowed the early uncontrolled use of radiation treatment for benign conditions. The subsequent recognition of the causal relationship between tumors and previous irradiation has restricted its use to more appropriate purposes, although it is possible that it is still overused in some areas of dermatologic practice. Clinicians need to be aware of the time interval between irradiation and the development of its late sequelae, and the incidence of these sequelae. Appropriate irradiation exposure history should be a part of the evaluation of every patient.

  19. Tejido adiposo como glándula endocrina. Implicaciones fisiopatológicas.

    Directory of Open Access Journals (Sweden)

    Illovis Ramírez Arteaga

    2011-08-01

    Full Text Available

    El tejido adiposo se considera en la actualidad como un órgano con importante función endocrina; distinguiéndose dos tipos: el pardo y el blanco. El tejido adiposo es capaz de secretar diversas sustancias conocidas como adipocinas que se encuentran implicadas en la regulación del peso corporal, en el sistema inmune, en la función vascular y en la sensibilidad insulínica. En la obesidad, principalmente visceral, se encuentran aumentadas las adipocinas proinflamatorias. Estas se asocian a la inflamación clínica y subclínica, a la insulinorresistencia, al estrés oxidativo y a la lesión endotelial; desarrollan un papel clave en el síndrome metabólico e incrementan el riesgo cardiometabólico. El objetivo de la presente revisión bibliográfica ha sido exponer las características morfofuncionales del tejido adiposo y los mecanismos que lo vinculan con la génesis de diversas enfermedades.

    ADIPOSE TISSUE AS AN ENDOCRINE GLAND. PATHOPHYSIOLOGICAL IMPLICATIONS.

    Adipose tissue is currently recognized as an organ with an important endocrine function. Two main types of adipose tissue are distinguished: the brown and the white. Adipose tissue can secrete a variety of substances known as adipokines that are implicated in the regulation of body weight, the immune system and the vascular functioning and the insulin sensitivity. In cases of obesity (mainly visceral obesity, proinflammatory adipokines are increased. They are commonly associated with clinical and subclinical inflammation, insulin resistance, oxidative stress and endothelial injury. Proinflammatory adipokines also play a key role in the metabolic syndrome and increase cardiometabolic risk. The present review is aimed at exposing the morphofunctional characteristics of adipose tissue and the mechanisms that link this tissue to the origin of a variety

  20. Perspectivas en disrupción endocrina Perspectives in endocrine disruption

    Directory of Open Access Journals (Sweden)

    N. Olea

    2002-06-01

    Full Text Available La descripción de alteraciones en la función reproductora de algunas especies de animales salvajes, junto a la demostración de la exposición humana y animal a sustancias químicas con actividad hormonal ­agonista y antagonista­ generó, hace dos décadas, lo que se conoce hoy día como hipótesis de disrupción endocrina. Se trata de un problema emergente de salud medioambiental que ha cuestionado algunos de los paradigmas en que se fundamenta el control y la regulación de uso de los compuestos químicos. La necesidad de incluir en los tests toxicológicos habituales nuevos objetivos de investigación, que se refieren específicamente al desarrollo y crecimiento de las especies y a la homeostasis y funcionalidad de los sistemas hormonales, ha venido a complicar tanto la evaluación de los nuevos compuestos químicos como la revaluación de los existentes. Sus repercusiones sobre la reglamentación y el comercio internacional no se han hecho esperar y a ambos lados del Atlántico se han diseñado y establecido sistemas de cribado de disruptores endocrinos y se han desarrollado programas de investigación con objeto de cualificar y cuantificar los efectos adversos sobre la salud humana y animal y poder actuar con medidas de prevención.Two decades ago, reports of alterations in the reproductive function of some wild animal species and clear evidence of human and animal exposure to chemical substances with hormonal activity ­agonist and antagonist­ generated what is known now as the hypothesis of endocrine disruption. This is an emerging environmental health problem that has challenged some of the paradigms on which the control and regulation of the use of chemical compounds is based. The need to include in routine toxicology tests new research objectives that specifically refer to the development and growth of species and to the homeostasis and functionality of hormonal systems, has served to complicate both the evaluation of new

  1. Neuropsychiatric sequelae of head injuries.

    Science.gov (United States)

    McAllister, T W

    1992-06-01

    Based on the above review several general points can be highlighted: Head injuries are extremely common, affecting probably close to 2,000,000 people in this country each year. The most common are nonmissile, closed-head injuries, the majority of which occur in association with motor vehicle accidents. Virtually all studies of head injury suggest a peak incidence in the 15 to 24 years of age group. Coarse measures of outcome suggest that the very young and the elderly have poorer outcomes. Because of improved acute care, however, a large number of young, otherwise healthy patients are surviving head injuries with a variety of profound neuropsychiatric sequelae. Because of the mechanics of brain injury in acceleration-deceleration injuries, certain brain injury profiles are common including orbitofrontal, anterior and inferior temporal contusions, and diffuse axonal injury. The latter particularly affects the corpus callosum, superior cerebellar peduncle, basal ganglia, and periventricular white matter. The neuropsychiatric sequelae follow from the above injury profiles. Cognitive impairment is often diffuse with more prominent deficits in rate of information processing, attention, memory, cognitive flexibility, and problem solving. Prominent impulsivity, affective instability, and disinhibition are seen frequently, secondary to injury to frontal, temporal, and limbic areas. In association with the typical cognitive deficits, these sequelae characterize the frequently noted "personality changes" in TBI patients. In addition, these changes can exacerbate premorbid problems with impulse control. Marked difficulties with substance use, sexual expression, and aggression often result. The constellation of symptoms, which make up the postconcussive syndrome, are seen across the whole spectrum of brain injury severity. Even in so-called mild or minor head injury, these symptoms are likely to have an underlying neuropathologic, neurochemical, or neurophysiologic cause

  2. Psychiatric sequelae of induced abortion.

    Science.gov (United States)

    Gibbons, M

    1984-03-01

    An attempt is made to identify and document the problems of comparative evaluation of the more recent studies of psychiatric morbidity after abortion and to determine the current consensus so that when the results of the joint RCGP/RCOG study of the sequelae of induced abortion become available they can be viewed in a more informed context. The legalization of abortion has provided more opportunities for studies of subsequent morbidity. New laws have contributed to the changing attitudes of society, and the increasing acceptability of the operation has probably influenced the occurrence of psychiatric sequelae. The complexity of measuring psychiatric sequelae is evident from the many terms used to describe symptomatology and behavioral patterns and from the number of assessment techniques involved. Numerous techniques have been used to quantify psychiatric sequelae. Several authors conclude that few psychiatric problems follow an induced abortion, but many studies were deficient in methodology, material, or length of follow-up. A British study in 1975 reported a favorable outcome for a "representative sample" of 50 National Health Service patients: 68% of these patients had an absence of or only mild feelings of guilt, loss, or self reproach and considered abortion as the best solution to their problem. The 32% who had an adverse outcome reported moderate to severe feelings of guilt, regret, loss, and self reproach, and there was evidence of mental illness. In most of these cases the adverse outcome was related to the patient's environment since the abortion. A follow-up study of 126 women, which compared the overall reaction to therapeutic abortion between women with a history of previous mild psychiatric illness and those without reported that a significantly different emotional reaction could not be demonstrated between the 2 groups. In a survey among women seeking an abortion 271 who were referred for a psychiatric opinion regarding terminations of pregnancy

  3. Neuropsychiatric sequelae of neuroleptic malignant syndrome.

    Science.gov (United States)

    Adityanjee; Sajatovic, Martha; Munshi, Kaizad R

    2005-01-01

    The authors review the literature on persistent sequelae of neuroleptic malignant syndrome (NMS). They highlight the clinical presentations, assessment, and management of persistent sequelae and stress the need to take preventive steps to minimize their occurrence. The authors conducted a Medline and PubMed search for papers on residual sequelae of NMS. They cross-referenced the available papers and "operationalized" the diagnostic criteria for persistent neuropsychiatric sequelae. A total of 31 cases of neuropsychiatric sequelae of NMS were identified. With reduction in mortality from NMS, persistent sequelae of NMS have assumed clinical importance. Long-term sequelae persist for weeks to months after amelioration of an acute episode. Individuals with a preexisting CNS insult are more predisposed to develop persistent sequelae. A high index of awareness for persistent sequelae is warranted because antipsychotics are widely used for psychiatric disorders besides schizophrenia. Awareness of such outcomes and the use of evidence-based strategies to minimize risk factors will help clinicians in reducing the persistent sequelae of NMS.

  4. Sequelae of pediatric osteoarticular infection.

    Science.gov (United States)

    Ilharreborde, B

    2015-02-01

    The epidemiology and diagnosis of osteoarticular infections (OAI) have changed considerably in recent years, partly due to the development of molecular biology. Kingella kingae is now recognized as the most frequent pathogen in children under 4 years of age, while methicillin-resistant Staphylococcus aureus (SA) has been increasingly reported. Although the clinical course of OAI is mostly benign, with shorter antibiotic regimens and simplified treatments, serious functional impairments and life-threatening complications can still occur, especially in case of delayed diagnosis or infection caused by Panton-Valentine leukocidin-producing strains of SA. Newborns and patients with sickle cell disease have greater risk of orthopaedic sequelae, which need to be detected and managed early. The main sequelae of osteomyelitis are angular limb deformity, due to partial growth arrest, and lower limb discrepancy. Therapeutic options are guided by the patient's age and predictions at maturity. The main complications of septic arthritis are joint stiffness and osteonecrosis. The procedures to consider are arthrodesis, joint reconstruction in immature children, and arthroplasty at the end of growth.

  5. Mielolipoma adrenal bilateral asociado a disfunción endocrina Bilateral adrenal myelolipoma associated with an endocrine dysfunction

    Directory of Open Access Journals (Sweden)

    Omaida F. Torres Herrera

    2010-08-01

    Full Text Available Se presentó un caso de mielolipoma adrenal bilateral asociado a hiperplasia adrenal congénita por déficit de enzima 21 hidroxilasa en un joven de 27 años de edad, que abandonó tratamiento sustitutivo con acetato de cortisona a los 14 años. Estuvo asintomático hasta su ingreso en el hospital, al cual es remitido por dolor abdominal, vómitos y fiebre, constatándose tumoración abdominal gigante en hemiabdomen izquierdo. Las características clínicas, hormonales y radiológicas halladas son comentadas y correlacionadas con lo registrado en la literatura médica. Hasta donde se revisó, es el primer caso de mielolipoma adrenal bilateral asociado a disfunción endocrina que se publica en Cuba.Authors present a case of bilateral adrenal myelolipoma associated with a congenital adrenal hyperplasia by deficit of hydroxilase enzyme 21 in a young aged 27 who leaves the substitution treatment with cortisone acetate at 14 years old. He was asymptomatic until its hospital admission due to abdominal pain, vomiting and fever and a high abdominal tumor in left hemi-abdomen. Clinical hormonal and radiological features founded are discussed and correlated with those registered in medical literature. As far as we know, this is the first case of bilateral adrenal myelolipoma associated with an endocrine dysfunction published in Cuba.

  6. Efecto de esteroides sexuales sobre la función endocrina adipocitaria e insulinosensibilidad periférica

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    A. Giovambattista

    2008-09-01

    Full Text Available Es conocido que las hormonas esteroideas sexuales modulan la composición corporal y otras funciones endocrinas. El objetivo del presente trabajo fue estudiar el impacto de la administración de esteroides sexuales sobre la insulinosensibilidad periférica y la función secretora adipocitaria. Grupos de ratas hembra recibieron vehículo (C o valerato de E2 o propionato de T. Se monitoreó el peso corporal y la ingesta de alimento hasta el día experimental, que fueron sacrificados en condición basal o sometidos a un test de sobrecarga con glucosa. Se evaluaron las concentraciones de leptina, E2, T, glucosa, triglicéridos e insulina (INS. Se ponderó el tejido adiposo parametrial y se aislaron los adipocitos e incubaron con o sin INS. E2 indujo una temprana (p Sex hormones are known to modulate body composition and endocrine functions. The aim of the present study was to analyze the impact of sexual steroids administration on the outlying insulin-sensibility and adipocyte secretory function. Groups of female rats received either vehicle (C, E2 valerate, or T propionate. Daily food intake and body weight were recorded until sacrifice under basal conditions or after high glucose load test. Plasma concentrations of leptin, E2, T, glucose, triglycerides, and insulin (INS were evaluated. The parametrial adipose tissue was pondered and adipocytes were isolated and then incubated with or without INS. E2 induced early hypophagia (p< 0,05; contrarily, T induced moderate hyperphagia (p<0,05. Weight and fatty parametrial mass values were lower for E2- than C-treated animals (p<0,05. Plasma levels remained unmodified either for E2 or T groups, though E2 animals developed hyperleptinemia (p<0.05. The high glucose load test showed increased and decreased insulin-sensitivity (p<0.05 in E2 and T groups, respectively. Finally, E2 and T isolated adipocytes were less sensitive to insulin-induced leptin secretion than C cells (p<0.05 vs. C. Our study reveals that

  7. Psychiatric sequelae of traumatic brain injury

    Directory of Open Access Journals (Sweden)

    Suprakash Chaudhury

    2013-01-01

    Full Text Available Almost half of the people suffering traumatic brain injury (TBI may later be diagnosed with psychiatric disorders. The literature (PubMed, IndMed of past 30 years on psychiatric disturbances associated with TBI is reviewed. The authors highlight the close link between head injury and psychiatry and provide an overview of the epidemiology, risk-factors, and mechanisms of psychiatric sequelae including, cognitive deficits, substance abuse, psychoses, mood disorders, suicide, anxiety disorders, dissociative disorders, post-concussion syndrome, and personality changes following head injury. The various psychiatric sequelae are briefly discussed.

  8. Modelos in vivo más usados para la identificación de disrupción endocrina potencial del aparato reproductor

    Directory of Open Access Journals (Sweden)

    Balia Pardo Acosta

    2009-01-01

    Full Text Available Actualmente, existe gran preocupación científica debido a los efectos que puede causar la exposición a sustancias químicas que tienen el potencial de provocar disrupción endocrina en la vida silvestre y los seres humanos. Diferentes organismos internacionales han propuesto diversas baterías de ensayos toxicológicos y bioensayos in vitro e in vivo para la identificación de disruptores endocrinos. El presente trabajo, por tanto, pretendió divulgar la metodología para realizar los ensayos in vivo que permiten identificar las sustancias que puedan conducir a la disrupción endocrina del aparato reproductor y que cumplen la condición de estar validados por la Organización para la Cooperación y Desarrollo Económico. El ensayo uterotrófico ha sido empleado para evaluar la actividad estrogénica o antiestrogénica en diferentes especies, principalmente en roedores tales como ratas hembras inmaduras y adultas ovariectomizadas. El ensayo de Hershberger es uno de los ensayos validados para determinar disruptores endocrinos potenciales en ratas machos castradas, en el cual la acción de un agonista o un antagonista androgénico puede ser identificada por el aumento o disminución significativo del peso de los órganos y tejidos sexuales de los animales tratados versus los controles. Los ensayos uterotrófico y de Hershberger son de fácil realización, sensibles y reproducibles, siendo muy útiles en la evaluación del potencial tóxico de nuevas sustancias.

  9. Maternal cigarette smoking during pregnancy and cognitive performance in adolescence

    National Research Council Canada - National Science Library

    Kafouri, S; Leonard, G; Perron, M; Richer, L; Séguin, JR; Veillette, S; Pausova, Z; Paus, T

    2009-01-01

    Background The incidence of cigarette smoking during pregnancy remains high. Maternal smoking during pregnancy is known to be associated with cognitive and behavioural sequelae in childhood and adolescence...

  10. Relationship violence in adolescence.

    Science.gov (United States)

    Lin, Alison J; Raymond, Marissa; Catallozzi, Marina; Ryan, Owen; Rickert, Vaughn I

    2007-12-01

    Previous experience with violence or a deficit in interpersonal skills may lead to violence in adolescent relationships. In this article we focus on various forms of interpersonal violence (bullying, sexual harassment, coercion, and relationship violence) that adolescents may experience and pay special attention to risk factors, help-seeking behaviors, and sequelae.

  11. Sequelae of Endoscopic Inguinal Hernia Repair : Incidence, evaluation and management

    NARCIS (Netherlands)

    Burgmans, J.P.J.

    2015-01-01

    The endoscopic preperitoneal technique (TEP) is an appealing inguinal hernia repair technique, theoretically superior to other approaches. In practice some problems remain unsolved. Real incidences of chronic postoperative inguinal pain (CPIP) and other important sequelae of endoscopic hernia repair

  12. Sequelae of Endoscopic Inguinal Hernia Repair : Incidence, evaluation and management

    NARCIS (Netherlands)

    Burgmans, J.P.J.

    2015-01-01

    The endoscopic preperitoneal technique (TEP) is an appealing inguinal hernia repair technique, theoretically superior to other approaches. In practice some problems remain unsolved. Real incidences of chronic postoperative inguinal pain (CPIP) and other important sequelae of endoscopic hernia repair

  13. Carcinoma medular de tiroides metastásico en mama en una paciente con diagnóstico clínico de neoplasia endocrina múltiple subtipo 2B: reporte de un caso

    OpenAIRE

    D’Angelo Piaggio, Lorenzo; Echecopar Sabogal, José; Chanamé Baca, Diego M.; Teruya Gibu, Alberto

    2016-01-01

    El carcinoma medular de tiroides (CMT) es un tipo de neoplasia maligna infrecuente, con alto índice metastásico. Se presenta como un solo nódulo en más del 70% de los casos, y los principales órganos de metástasis a distancia son el hígado, el pulmón y el hueso. La metástasis en mama es rara, debido a que dentro de los tumores mamarios, solo entre el 0.2-1.3% son secundarios. El CMT se relaciona íntimamente con la neoplasia endocrina múltiple subtipo 2B (NEM2B), la cual es un desorden autosóm...

  14. Ocular sequelae from the illicit use of class A drugs

    OpenAIRE

    Firth, A Y

    2004-01-01

    Aim: To highlight the changes that may take place in\\ud the visual system of the class A drug abuser.\\ud \\ud \\ud Methods: A literature review was carried out of\\ud ocular/visual sequelae of the more common class A\\ud drugs. These include stimulants (cocaine and crack\\ud cocaine), narcotics (heroin, morphine, methadone)\\ud and hallucinogenics (ecstasy, lysergic acid diethylamide,\\ud magic mushrooms, mescaline, phencyclidine).\\ud \\ud \\ud Results: Ocular sequelae affecting visual acuity, the\\ud ...

  15. Aesthetic skin branding: a novel form of body art with adverse clinical sequela.

    Science.gov (United States)

    Karamanoukian, Raffy; Ukatu, Chidi; Lee, Edward; Hyman, Josh; Sundine, Michael; Kobayashi, Mark; Evans, Gregory R D

    2006-01-01

    Branding is a form of body art wherein third-degree burns are inflicted on the skin to produce permanent scars. This method of scarification is a common practice among many indigenous cultures and has become exceedingly common in western societies. As with other forms of body art, branding is not a manifestation of a psychiatric disorder but, rather, a method of self-expression. The process can be performed through the use of electrocautery, laser, chemicals, freezing, and hot metal. Complications arising from the procedure include acute infection, transmission of blood-borne pathogens, allergic reactions, and sequelae arising from third-degree burns. In addition, skin branding has been shown to be associated with substance abuse and high-risk behaviors among adolescents. The purpose of this article is to present the following case report and review to familiarize clinicians with this dangerous method of body art.

  16. Chronic otitis media sequelae in skeletal material from medieval Denmark

    DEFF Research Database (Denmark)

    Qvist, M; Grøntved, A M

    2001-01-01

    OBJECTIVES: Chronic otitis media sequelae (COMS) have been identified in archaeological skeletal materials from various ages. COMS reflecting episodes of upper respiratory tract infection may be used as a paleopathological indicator of general health. Estimation of the frequency of COMS may...

  17. Complex Sequelae of Psychological Trauma Among Kosovar Civilian War Victims

    NARCIS (Netherlands)

    Morina, N.; Ford, J.D.

    2008-01-01

    Aims: The impact of war trauma on civilians may include, but also extend beyond, post-traumatic stress disorder (PTSD) to include complex sequelae such as those described by the syndrome of Disorders of Extreme Stress Not Otherwise Specified (DESNOS). Methods: In the present study, 102 civilian war

  18. Sinus of Valsalva Pseudoaneurysm as a Sequela to Infective Endocarditis

    Science.gov (United States)

    Siegel, Robert J.

    2016-01-01

    Pseudoaneurysm is an uncommon sequela of infective endocarditis. We treated a 44-year-old man who had an active case of group B streptococcal infective endocarditis of the aortic valve despite no evidence of valvular dysfunction or vegetation on his initial transesophageal echocardiogram. After completing 6 weeks of intravenous antibiotic therapy, the patient developed a sinus of Valsalva pseudoaneurysm and severe aortic regurgitation caused by partial detachment of the left coronary cusp. We used a pericardial patch to close the pseudoaneurysm and repair the coronary cusp. This case shows the importance of routine clinical follow-up evaluation in infective endocarditis, even after completion of antibiotic therapy. Late sequelae associated with infective endocarditis or its therapy include recurrent infection, heart failure caused by valvular dysfunction (albeit delayed), and antibiotic toxicity such as aminoglycoside-induced nephropathy and vestibular toxicity. PMID:27047285

  19. Sequelae og død efter pneumokokmeningitis

    DEFF Research Database (Denmark)

    Korsholm, Jakob; Kristensen, Rasmus Nygård; Heslop, Anders;

    2009-01-01

    consciousness. The mortality was 11%, and 40% of the surviving population developed permanent sequelae, of which 88% suffered loss of hearing. Sixty one percent was not evaluated audiologically after hospitalization. CONCLUSION: Pre-admission antibiotics were associated with a decreased risk of death......INTRODUCTION: The aim was to evaluate prognostic factors and outcome parameters related to otogenic pneumococcal meningitis (OPM). MATERIALS AND METHODS: Retrospective analysis of patients with OPM in Aarhus County from 1994 to 2003. RESULTS: Seventy patients were included, corresponding...... and sequelae. Affected consciousness was a significant prognostic factor. The mortality rate was four times higher among adults than among children. Mastoidectomy was performed in 56% of adults without any significant influence on the outcome. Based on the presented results it appears relevant to treat cases...

  20. Sinus of Valsalva Pseudoaneurysm as a Sequela to Infective Endocarditis.

    Science.gov (United States)

    Lee, Chin C; Siegel, Robert J

    2016-02-01

    Pseudoaneurysm is an uncommon sequela of infective endocarditis. We treated a 44-year-old man who had an active case of group B streptococcal infective endocarditis of the aortic valve despite no evidence of valvular dysfunction or vegetation on his initial transesophageal echocardiogram. After completing 6 weeks of intravenous antibiotic therapy, the patient developed a sinus of Valsalva pseudoaneurysm and severe aortic regurgitation caused by partial detachment of the left coronary cusp. We used a pericardial patch to close the pseudoaneurysm and repair the coronary cusp. This case shows the importance of routine clinical follow-up evaluation in infective endocarditis, even after completion of antibiotic therapy. Late sequelae associated with infective endocarditis or its therapy include recurrent infection, heart failure caused by valvular dysfunction (albeit delayed), and antibiotic toxicity such as aminoglycoside-induced nephropathy and vestibular toxicity.

  1. Cranial MR imaging of sequelae of prefrontal lobotomy.

    Science.gov (United States)

    Uchino, A; Kato, A; Yuzuriha, T; Takashima, Y; Kudo, S

    2001-02-01

    Although prefrontal lobotomy is an obsolete treatment for schizophrenia, we still encounter patients who have undergone this procedure. The purpose of this study was to describe the MR imaging findings of sequelae of prefrontal lobotomy. We retrospectively reviewed cranial MR images of eight patients with schizophrenia who underwent prefrontal lobotomy approximately 50 years previously. In all patients, a bilateral cavitary lesion with a thick wall was found in the frontal white matter. The genu of the corpus callosum was mildly to markedly atrophic. The size and location of the cavity and the degree of callosal atrophy were correlated. MR imaging is useful for the diagnosis of sequelae of prefrontal lobotomy, including cavitary lesions with dense walls of gliosis and secondary degeneration of the genu of the corpus callosum.

  2. Acute viral bronchiolitis and its sequelae in developing countries.

    Science.gov (United States)

    Fischer, Gilberto Bueno; Teper, Alejandro; Colom, Alejandro J

    2002-12-01

    Acute viral bronchiolitis (AVB) is a common disease found throughout the world. Various aspects of it are being studied: its epidemiology, diagnosis, prognosis and treatment. Most of these studies are being conducted in developed countries, with only a few taking place in developing countries. Risk factors such as poor nutrition, an adverse environment and early weaning should be studied where these features are common. Treatment aspects such as cost-effectiveness in low income settings need further study. Use of ribavirin and respiratory syncytial virus (RSV)-immunoglobulin are good examples. Post-bronchiolitic sequelae also need to be studied in low income countries. There is evidence that bronchiolitis obliterans is unusually frequent in some Latin-American countries such as Argentina and Brazil. It will be helpful to undertake combined studies in countries with the same socio-economics, investigating the preventive and management aspects of AVB and its sequelae to reduce the morbidity and mortality.

  3. Long-term cognitive sequelae of antenatal maternal anxiety: involvement of the orbitofrontal cortex.

    Science.gov (United States)

    Mennes, Maarten; Stiers, Peter; Lagae, Lieven; Van den Bergh, Bea

    2006-01-01

    Anxiety and stress experienced by the mother during pregnancy are reported to have a negative association with the cognitive development of the child. An integration of recent evidence from cognitive reaction time tasks pointed to a deficit in endogenous response inhibition, a function ascribed to prefrontal cortex. To further delineate the cognitive sequelae associated with antenatal maternal anxiety, we reviewed recent neuro-imaging literature to create a cortical map of regions commonly and selectively activated by well-known cognitive tasks. The pragmatic value of this cortical map was tested in a follow-up sample of 49 17-year old adolescents. Adolescents of mothers with high levels of anxiety during week 12-22 of their pregnancy performed significantly lower in tasks which required integration and control of different task parameters. Working memory, inhibition of a prepotent response, and visual orienting of attention were not impaired. Based on the established cortical map, these results were related to subtle developmental aberrations in a part of, or in cortical and sub-cortical regions linked to, the orbitofrontal cortex.

  4. Lacrimal excretory system sequelae in patients treated for leishmaniasis

    OpenAIRE

    Hoyama,Erika; Schellini,Silvana Artioli; Stolf,Hamilton Ometo; Nakajima,Vitor

    2006-01-01

    Leishmaniasis infection may involve destruction of nasal tissues resulting in lacrimal drainage system alteration. PURPOSE: To evaluate the frequency of lacrimal excretory system sequelae in patients treated for leishmaniasis. METHODS: Forty-five leishmaniasis-treated patients (90 nasolacrimal ducts) were submitted to lacrimal excretory system evaluation. All were evaluated by Jones I test and when it was abnormal, dacryocystography and nasal endoscopy were performed. This situation occurred ...

  5. Otitis Media and Its Sequelae in Kenyan Schoolchildren.

    Science.gov (United States)

    Simões, Eric A F; Kiio, Francis; Carosone-Link, Phyllis J; Ndegwa, Serah N; Ayugi, John; Macharia, Isaac M

    2016-12-01

    The goal of this study was to obtain representative Kenyan data on the point prevalence of acute otitis media (AOM) and its sequelae (otitis media with effusion [OME] and chronic suppurative otitis media [CSOM]), a major cause of preventable hearing loss in children in developing countries. In Africa, there are limited studies on the prevalence of AOM and its sequelae in children. Study subjects were children aged 2 to 15 years and were enrolled from randomly selected preprimary and primary schools. After parental or guardian consent, subjects had a questionnaire administered, otoscopy and tympanometry were done, and audiometry was performed on those with ear problems detected on these examinations. A total of 9825 (75%) children was from rural schools. The prevalence of CSOM was 15 of 1000, OME was 15 of 1000, and AOM was 7 of 1000 children. Rural Rift Valley schoolchildren had the highest prevalence of CSOM (24 of 1000) compared with other regions (12 of 1000; P < .0001). Ear discharge occurred before 3.5 years in 50% of 901 children with ear discharge. A history of ear discharge was associated with abnormal tympanograms (odds ratio [OR], 11.9-19.2) and mild-to-severe hearing loss (OR, 21.6-38.6), even in children without ear disease (OR, 10.7-24.4). The burden of AOM sequelae in Kenyan preschool and schoolchildren is significant, and it occurs mostly in the first 4 years of life. By preventing early recurrent AOM, pneumococcal vaccination might partly avert nonreversible sequelae. © The Author 2015. Published by Oxford University Press on behalf of the Pediatric Infectious Diseases Society. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  6. Life without the vein of Galen: Clinical and radiographic sequelae.

    Science.gov (United States)

    Youssef, A Samy; Downes, Angela E; Agazzi, Siviero; Van Loveren, Harry R

    2011-09-01

    A thorough understanding of the anatomy of the pineal region, particularly venous drainage, is critical for gaining open surgical access to the pineal gland. The adverse sequelae after intraoperative venous occlusion are assumed to be catastrophic but have been scarcely reported. We report a case of pineocytoma in which the vein of Galen was ligated without postoperative adverse sequelae. Pineal region anatomy with emphasis on deep veins was reviewed in large anatomical studies. There are tremendous anatomical variations in the vein of Galen and its tributaries. Several confounding factors can be encountered during surgery and may lead to accidental sacrifice of the vein of Galen. Survival after focal occlusion of a major deep vein depends on the development of collateral circulation as shown in our case report. Venous drainage remains the cornerstone in the surgical planning of the pineal region. Anatomical variations and venous collaterals undoubtedly contributed to the mixed reports of adverse sequelae after venous sacrifice. Vein of Galen ligation may be survivable but consequences cannot be predicted without a thorough pre-ligation assessment of regional venous collateral drainage. Thorough understanding of the venous anatomy, meticulous planning of the surgical approach and avoidance of the occlusion of the vein of Galen and its major tributaries are key factors to successful pineal region surgery.

  7. El desafío de vivir con enfermedades endocrinas: algunas anotaciones para la atención en salud The challenge of living with endocrine diseases: some annotations for health care

    Directory of Open Access Journals (Sweden)

    Loraine Ledón Llanes

    2008-08-01

    Full Text Available Las enfermedades endocrinas son vividas con mucha frecuencia como experiencias profundamente demandantes y complejas debido a su impacto sobre el cuerpo y la psiquis de la persona, a sus significados sociales, y a las interacciones que demandan en los diversos espacios de la vida. El presente trabajo recoge la experiencia de varios años en los espacios de asistencia e investigación en salud con personas que viven con enfermedades endocrinas, a partir de la integración de los momentos, áreas y dimensiones que parecen tener mayor significación desde sus vivencias. Se tratan como temas fundamentales: el impacto de la enfermedad y los contenidos con los que usualmente se relaciona el momento del diagnóstico, la búsqueda y comprensión del origen de la enfermedad, entre otros; las acciones que mujeres y varones desarrollan para afrontar el proceso de salud-enfermedad e integrarlo a la vida cotidiana; y las evaluaciones y valoraciones generales de sus experiencias, con énfasis en sus dimensiones positivas y de aprendizaje. El trabajo culmina con recomendaciones que se consideran fundamentales en el trabajo en este campo para incidir favorablemente en el mejoramiento de la calidad de vida y bienestar de estas personas.Endocrine diseases are very frequently lived as deeply demanding and complex experiences due to their impact on the body and the psyche of the person, to their social meanings and to the interactions they demand in the diverse spaces of life. The present paper is based on the experience accumulated during several years in the fields of health care and research with persons suffering from endocrine diseases, starting from the integration of the moments, areas and dimensions that seem to have a greater significance from their personal experiences. Some of the fundamental topics approached are the impact of the disease and the contents with which the moment of diagnosis, and the search and understanding of the origin of the disease

  8. Latissimus dorsi transposition for sequelae of obstetric palsy

    Directory of Open Access Journals (Sweden)

    Enrique Vergara- Amador

    2010-10-01

    Full Text Available Background: In obstetric palsy, limitation in the external abduction and rotation of the shoulder is the most frequent sequelae. Glenohumeral deformity is the result of muscular imbalance between the external and internal rotators. Releasing the contracted muscles and transferring the latissimus dorsi are the most common surgeries in this case. Patients and methods: We operated on 24 children between 4 and 8 years of age with obstetric palsy sequelae to elevate the subscapularis muscle off the anterior surface of the scapula posteriorly and transfer the latissimus dorsi. The patients received a minimum of 2 years of follow up. They were evaluated based on Mallet’s and Gilbert’s classifications. Results: All of the patients recovered within the above mentioned classifications. Out of 22 children evaluated via Mallet’s classification, all improved from 3 to 4 on that scale. With respect to Gilbert’s classification, 16 children improved one degree and 8 improved 2 degrees. All of the patients’ parents were satisfied with the results. Discussion: The benefit from releasing contracted muscles and muscle transfer to improve shoulder abduction in the sequelae of obstetric palsy has been amply reported in the literature. The results we had from elevating the subscapularis muscle off the anterior surface of the scapula and transferring the latissimus dorsi were good. Children who were difficult to classify based on the described scale were taken note of and some sub-classifications for Gilbert’s descriptions were proposed. Patients must be selected carefully. To transfer the latissimus dorsi, it is necessary to have good passive mobility in abduction, a minimum of 20º of external rotation and no joint deformities. When negative external rotation is found, the subscapularis muscle should be released. When there is glenohumeral joint deformity in older children, other methods are recommended, such as rotational humeral osteotomy.

  9. [Post-treatment sequelae after breast cancer conservative surgery].

    Science.gov (United States)

    Delay, E; Gosset, J; Toussoun, G; Delaporte, T; Delbaere, M

    2008-04-01

    Thanks to the earlier detection of breast cancer, the advent of neoadjuvant therapy and the development of more effective surgical procedures reducing treatment sequelae, conservative treatment has dramatically expanded over the past 15 years. Several factors have recognized negative aesthetic consequences for breast cancer patients: being overweight, having voluminous or on the contrary, very small breasts, having a tumor located in the lower quadrant, having high breast-tumor: breast-volume ratio. Tissue injuries induced by radiotherapy and chemotherapy, such as shrinking, fibrosis or induration, maximize the deleterious impact of surgery. The results of conservative treatment also deteriorate with time: weight gain is common and may result in increased breast asymmetry. Patients undergoing conservative treatment may experience sequelae including various degrees of the following dimorphisms, all possibly responsible for minor or even major breast deformity: breast asymmetry, loss of the nipple/areola complex, scar shrinkage and skin impairment, irregular shape and position of the nipple and areola. Various sensory symptoms have also been reported following conservative treatment, with patients complaining of hypo- or dysesthesia or even suffering actual pain. Breast lymphedema is also a common incapacitating after-effect that is believed to be largely underdiagnosed in clinical practice. Finally, like mastectomy, conservative breast surgery may induce serious psychological distress in patients who suffer the loss of physical integrity, womanhood or sexual arousal. Clinicians must be aware of the radiological changes indicative of late cancer recurrence. There are four types of modifications as follows: increased breast density, architectural distortion at the surgical site and formation of scar, mammary fat necrosis, and occurrence of microcalcifications. The management of sequelae of conservative breast treatment must therefore involve a multidisciplinary

  10. Latissimus dorsi transposition for sequelae of obstetric palsy

    Directory of Open Access Journals (Sweden)

    Enrique Vergara-Amador

    2010-09-01

    Full Text Available Background: In obstetric palsy, limitation in the external abduction and rotation of the shoulder is the most frequent sequelae. Glenohumeral deformity is the result of muscular imbalance between the external and internal rotators. Releasing the contracted muscles and transferring the latissimus dorsi are the most common surgeries in this case.Patients and methods: We operated on 24 children between 4 and 8 years of age with obstetric palsy sequelae to elevate the subscapularis muscle off the anterior surface of the scapula posteriorly and transfer the latissimus dorsi. The patients received a minimum of 2 years of follow up. They were evaluated based on Mallet’s and Gilbert’s classifications.Results: All of the patients recovered within the above mentioned classifications. Out of 22 children evaluated via Mallet’s classification, all improved from 3 to 4 on that scale. With respect to Gilbert’s classification, 16 children improved one degree and 8 improved 2 degrees. All of the patients’ parents were satisfied with the results.Discussion: The benefit from releasing contracted muscles and muscle transfer to improve shoulder abduction in the sequelae of obstetric palsy has been amply reported in the literature. The results we had from elevating the subscapularis muscle off the anterior surface of the scapula and transferring the latissimus dorsi were good. Children who were difficult to classify based on the described scale were taken note of and some sub-classifications for Gilbert’s descriptions were proposed. Patients must be selected carefully. To transfer the latissimus dorsi, it is necessary to have good passive mobility in abduction, a minimum of 20º of external rotation and no joint deformities. When negative external rotation is found, the subscapularis muscle should be released. When there is glenohumeral joint deformity in older children, other methods are recommended, such as rotational humeral osteotomy.

  11. Sequelae og død efter pneumokokmeningitis

    DEFF Research Database (Denmark)

    Korsholm, Jakob; Kristensen, Rasmus Nygård; Heslop, Anders

    2009-01-01

    consciousness. The mortality was 11%, and 40% of the surviving population developed permanent sequelae, of which 88% suffered loss of hearing. Sixty one percent was not evaluated audiologically after hospitalization. CONCLUSION: Pre-admission antibiotics were associated with a decreased risk of death...... of AOM, especially in adults with early antimicrobials due to their higher relative risk of developing OPM and the related risk of a poor outcome. In addition, maintenance of the previously established treatment regimen in OPM followed by audiological control is recommended. Udgivelsesdato: 2009-Apr-27...

  12. [Moderate sequelae secondary to noma: value of the nasogenal flap].

    Science.gov (United States)

    Trendel, D; Martin, J P; Martins-Carvalho, C

    2009-02-01

    Noma is a gangrenous disease leading to destruction of soft and hard tissue of the face. It mainly affects young poor children with poor oral care. Without treatment noma is fatal in 70 to 90% of cases. In survivors, esthetic and functional sequelae are severe. Emergency intravenous antibiotherapy improves survival but restoration of the face requires reconstructive surgery. Different surgical techniques with various degrees of complexity and reliability have been proposed. The purpose of this article is to describe the nasogenal flap technique. This simple, single-stage technique is well suited to conditions in Africa.

  13. Laryngeal sequelae due to accidental inhalation of anhydrous ammonia

    Directory of Open Access Journals (Sweden)

    Cruz, Walter Paiva

    2009-03-01

    Full Text Available Introduction: Anhydrous Ammonia (AA is a caustic compound commonly used in the industry that can cause burns, even with brief contact. As with other alkali burns, the early washing to remove the AA from burnt areas is crucial to limit tissue damage. The concentration of toxic agent and duration of its contact determine the degree of skin and mucosa destruction. A tanker truck carrying AA (NH3 fell off a highway, and released a dense cloud of AA gas. Fifty-four people inhaled the gas and after ninety days, three people were still experiencing hoarseness and were examined. Case Report: We assessed three patients with laryngeal sequelae due to AA inhalation burn. We found a case of hyperemia and edema, one case of granuloma of the posterior third portion of the left vocal cord, and one case of vocal cord adhesion. Necropsy findings are commented both macroscopically and microscopically. The sequelae and the best treatments for them are discussed herein.

  14. Vitiligo iridis and glaucoma: a rare sequelae of small pox.

    Science.gov (United States)

    Kavitha, S; Patel, S R; Mohini, P; Venkatesh, R; Sengupta, S

    2015-10-01

    Vitiligo iridis refers to focal areas of iris atrophy as sequelae of small pox infection. We report a series of patients with unilateral vitiligo iridis, some of whom presented with secondary open-angle glaucoma. Three patients with vitiligo iridis underwent a comprehensive ophthalmic examination including intraocular pressure (IOP) measurement, slit lamp biomicroscopy, gonioscopy, and fundus evaluation. Patients' facial features were also documented and photographed. All patients were in their sixth decade. Two out the three had elevated IOP (52 mm Hg and 36 mm Hg) in the same eye as vitiligo iridis, at initial presentation. Gonioscopy showed patchy iris hyperpigmentation and fundus evaluation showed glaucomatous optic disc changes in the involved eye. One patient responded favourably to topical antiglaucoma medications, whereas the other was taken up for combined phacoemulsification-trabeculectomy with good results. The third patient had normal IOP in the involved eye. All three patients gave a history of small pox in childhood and had pitted facial scars typical of previous small pox infection. Vitiligo iridis may be associated with the secondary glaucoma as a long-term sequelae of small pox. It may be prudent to periodically follow-up such patients for development of raised IOP in the future.

  15. Acute trauma induced disc displacement without reduction and its sequelae

    Science.gov (United States)

    He, DongMei; Yang, XiuJuan; Wang, FeiYu; Yang, Chi; Dong, MinJun

    2016-01-01

    Acute traumatic temporomandibular joint disc displacement (ATDD) and its sequelae are not familiar for most surgeons. This study is to discuss its sequelae in cases without disc reduction after failed conservative treatment. From 2010 to 2015, 26 patients with 34 joints were included in the study. All patients had at least 3 months conservative treatment. Their maximal incisor opening (MIO) was measured during follow-ups and MRI examination was used to check the condylar bone degeneration. The mean follow-up for conservative treatment after admission was 8.69 months, the patients reached an average of 25.7 mm MIO. MRI showed condylar bone intact in 8 joints (23.5%), condylar surface bone destruction (Wilks IV, V stages) in 14 joints (41.2%), and severe bone resorption in 12 joints (35.3%). 15 patients with 23 joints were asked for surgical treatment after a mean conservative treatment of 5.4 months (3–12 months) to improve mouth opening and relieve chronic pain. 12 joints had total joint replacement (TJR). 11 joints had disc repositioning. Their mean MIO before operation was 19.8 mm and significantly improved to 33.9 mm after operation (p = 0.0000). ATDD may cause severe osteoarthritis or ankylosis. Disc repositioning and TJR could significantly improve MIO. PMID:27582054

  16. Anesthesia awareness: narrative review of psychological sequelae, treatment, and incidence.

    Science.gov (United States)

    Bruchas, Robin R; Kent, Christopher D; Wilson, Hilary D; Domino, Karen B

    2011-09-01

    Awareness during general anesthesia occurs when patients recall events or sensations during their surgeries, although the patients should have been unconscious at the time. Anesthesiologists are cognizant of this phenomenon, but few discussions occur outside the discipline. This narrative review summarizes the patient recollections, psychological sequelae, treatment and follow-up of psychological consequences, as well as incidence and etiology of awareness during general anesthesia. Recalled memories include noises, conversations, images, mental processes, feelings of pain and/or paralysis. Psychological consequences include anxiety, flashbacks, and posttraumatic stress disorder diagnosis. Limited discussion for therapeutic treatment after an anesthesia awareness experience exists. The incidence of anesthesia awareness ranges from 0.1 to 0.2% (e.g., 1-2/1000 patients). Increased recognition of awareness during general anesthesia within the psychological/counseling community, with additional research focusing on optimal therapeutic treatment, will improve the care of these patients.

  17. Severe ocular sequelae of congenital toxoplasmosis: huge macular scar.

    Science.gov (United States)

    Zahir, Fadoua; Abdellaoui, Meriem; Younes, Samar; Benatiya, Idriss A; Tahri, Hicham

    2015-01-01

    Retinochoroiditis is the most common ocular manifestation of congenital toxoplasmosis, but other associated ophthalmological pathologies can also occur. Ophthalmologists are rarely able to distinguish between toxoplasmic retinochoroiditis due to infection acquired before or after birth, unless other clinical or serological indications are present. This article reports a case of a 3-year-old boy with abnormalities suggestive of congenital toxoplasmosis. The clinical and complementary examinations are discussed. The education of pregnant women is crucial for the prevention of congenital toxoplasmosis. Awareness of antenatal and postnatal presenting signs and symptoms is important for clinicians, because early diagnosis and treatment may minimize sequelae. Untreated, the majority of affected infants will develop chorioretinitis, deafness and/or neurological symptoms.

  18. [Doppler ultrasonography in children with sequelae of acute neuroinfections].

    Science.gov (United States)

    Rosin, Iu A

    1999-01-01

    Transcranial dopplerography was performed in 125 children with late (1-3 years) neurologic sequelae of acute neuroinfections. Decreased blood flow velocity (BFV) in middle cerebral arteries of (0.61 of the value in control group) was found in patients with movement disorders. Impairment of the intracranial venous outflow together with both acceleration and asymmetry of blood flow in basal veins was prevalent in children with intracranial hypertension and hydrocephaly syndrome. Hyperconstriction of cerebral vessels together with a low BFV (30% of the initial value) was observed during hyperventilation on the side of the lesion in patients with epileptic syndrome. In children with cerebrasthenic syndrome the effect of cavinton treatment depended on the type of changes in cerebral blood flow: positive effect was found in patients with asymmetric decrease of BFV in anterior cerebral arteries.

  19. Management of the Sequelae of Severe Congenital Abdominal Wall Defects

    Directory of Open Access Journals (Sweden)

    Sara Fuentes

    2016-05-01

    Full Text Available BackgroundThe survival rate of newborns with severe congenital abdominal wall defects has increased. After successfully addressing life-threatening complications, it is necessary to focus on the cosmetic and functional outcomes of the abdominal wall.MethodsWe performed a chart review of five cases treated in our institution.ResultsFive patients, ranging from seven to 18 years of age, underwent the following surgical approaches: simple approximation of the rectus abdominis fascia, the rectus abdominis sheath turnover flap, the placement of submuscular tissue expanders, mesh repair, or a combination of these techniques depending on the characteristics of each individual case.ConclusionsPatients with severe congenital abdominal wall defects require individualized surgical treatment to address both the aesthetic and functional issues related to the sequelae of their defects.

  20. [Perspectives of cell therapy in sequelae from cerebrovascular accidents].

    Science.gov (United States)

    Otero, Laura; Zurita, Mercedes; Bonilla, Celia; Aguayo, Concepción; Rico, Miguel Angel; Vaquero, Jesús

    2012-09-01

    Spontaneous intracerebral hemorrhage (ICH) is associated with mortality between 40 and 50% of cases. Among the survivors, only 10% are independent after one month, there is no effective treatment of sequelae, except for the limited possibilities providing for rehabilitation. We review the current experience with intracerebral transplantation of mesenchymal stem cells (MSCs) obtained from bone marrow as a potential treatment of neurological sequelae occurring after experimental ICH. We describe the model of ICH by intracerebral administration of collagenaseIV at basal ganglia level in Wistar rats. Neurological deficits caused by ICH can be quantified through a variety of functional assessment test (NMSS, Rota-rod, VTB-test). 5×10allogeneic MSCs in 10μl of saline were administered intracerebrally in 10 animals, 2 months after ICH. In another 10 animals (controls) the same volume of saline was administered. Changes in the functional deficits were assessed during the next 6 months in both experimental groups. The results suggested therapeutic efficacy of MSCs transplantation and showed that transplanted stem cells can survive in the injured brain, transforming into neurons and glial cells. This form of cell therapy induces reactivation of endogenous neurogenesis at the subventricular zone (SVZ) and achieves antiapoptotic protective effect in the injured brain. Cell therapy represents an important field of research with potential clinical application to treatment of neurological sequels, currently considered irreversible. Neurosurgeons should become involved in the development of these new techniques that are likely to shape the future of this specialty. Copyright © 2011 Sociedad Española de Neurocirugía. Published by Elsevier España. All rights reserved.

  1. Skeletal sequelae of radiation therapy for malignant childhood tumors

    Energy Technology Data Exchange (ETDEWEB)

    Butler, M.S.; Robertson, W.W. Jr.; Rate, W.; D' Angio, G.J.; Drummond, D.S. (UMDNJ Robert Wood Johnson Medical School, New Brunswick (USA))

    1990-02-01

    One hundred forty-three patients who received radiation therapy for childhood tumors, and survived to the age of skeletal maturity, were studied by retrospective review of oncology records and roentgenograms. Diagnoses for the patients were the following: Hodgkin's lymphoma (44), Wilms's tumor (30), acute lymphocytic leukemia (26), non-Hodgkin's lymphoma (18), Ewing's sarcoma (nine), rhabdomyosarcoma (six), neuroblastoma (six), and others (four). Age at the follow-up examination averaged 18 years (range, 14-28 years). Average length of follow-up study was 9.9 years (range, two to 18 years). Asymmetry of the chest and ribs was seen in 51 (36%) of these children. Fifty (35%) had scoliosis; 14 had kyphosis. In two children, the scoliosis was treated with a brace, while one developed significant kyphosing scoliosis after laminectomy and had spinal fusion. Twenty-three (16%) patients complained of significant pain at the radiation sites. Twelve of the patients developed leg-length inequality; eight of those were symptomatic. Three patients developed second primary tumors. Currently, the incidence of significant skeletal sequelae is lower and the manifestations are less severe than reported in the years from 1940 to 1970. The reduction in skeletal complications may be attributed to shielding of growth centers, symmetric field selection, decreased total radiation doses, and sequence changes in chemotherapy.

  2. Deoxynivalenol-Induced Proinflammatory Gene Expression: Mechanisms and Pathological Sequelae

    Directory of Open Access Journals (Sweden)

    James J. Pestka

    2010-06-01

    Full Text Available The trichothecene mycotoxin deoxynivalenol (DON is commonly encountered in human cereal foods throughout the world as a result of infestation of grains in the field and in storage by the fungus Fusarium. Significant questions remain regarding the risks posed to humans from acute and chronic DON ingestion, and how to manage these risks without imperiling access to nutritionally important food commodities. Modulation of the innate immune system appears particularly critical to DON’s toxic effects. Specifically, DON induces activation of mitogen-activated protein kinases (MAPKs in macrophages and monocytes, which mediate robust induction of proinflammatory gene expression—effects that can be recapitulated in intact animals. The initiating mechanisms for DON-induced ribotoxic stress response appear to involve the (1 activation of constitutive protein kinases on the damaged ribosome and (2 autophagy of the chaperone GRP78 with consequent activation of the ER stress response. Pathological sequelae resulting from chronic low dose exposure include anorexia, impaired weight gain, growth hormone dysregulation and aberrant IgA production whereas acute high dose exposure evokes gastroenteritis, emesis and a shock-like syndrome. Taken together, the capacity of DON to evoke ribotoxic stress in mononuclear phagocytes contributes significantly to its acute and chronic toxic effects in vivo. It is anticipated that these investigations will enable the identification of robust biomarkers of effect that will be applicable to epidemiological studies of the human health effects of this common mycotoxin.

  3. Some musculo-skeletal sequelae in cancer survivors.

    Science.gov (United States)

    Aksnes, Liv Hege; Bruland, Øyvind Sverre

    2007-01-01

    This paper deals with some of the musculo-skeletal complication that can occur after cancer treatment. In particular, we focus on Cancer Treatment Induced Bone Loss (CTIBL) and the musculo-skeletal complications that can occur in patients treated for extremity sarcoma. In addition we discuss peripheral neuropathy, musculo-skeletal pain and briefly mention some of the complications related to radiotherapy. CTIBL is mostly studied in breast cancer and prostate cancer survivors. The cause in these groups is mainly due to treatment induced hypogonadism. Other causes of CTIBL are indirect or direct cause of chemotherapy, physical inactivity and inadequate intake of vitamin D and calcium. Treatment of CTIBL consists of diet and lifestyle changes and pharmacological intervention. Extremity bone sarcomas constitute a special group since they often experience mutilating surgery and heavy combination chemotherapy. The treatment results in worse function than the normal population and the amputated usually have lower physical functioning than patients treated with limb sparing surgery (LSS). However, most studies fail to show differences in quality of life between the amputated and LSS. Most of the studies performed on musculo-skeletal sequelae have been done on survivors of childhood cancer, breast cancer or prostate cancer. More studies among the other cancer groups are needed to reveal the extent and prevalence of these complications.

  4. Survival without sequelae after prolonged cardiopulmonary resuscitation after electric shock.

    Science.gov (United States)

    Motawea, Mohamad; Al-Kenany, Al-Sayed; Hosny, Mostafa; Aglan, Omar; Samy, Mohamad; Al-Abd, Mohamed

    2016-03-01

    "Electrical shock is the physiological reaction or injury caused by electric current passing through the human body. It occurs upon contact of a human body part with any source of electricity that causes a sufficient current through the skin, muscles, or hair causing undesirable effects ranging from simple burns to death." Ventricular fibrillation is believed to be the most common cause of death after electrical shock. "The ideal duration of cardiac resuscitation is unknown. Typically prolonged cardiopulmonary resuscitation is associated with poor neurologic outcomes and reduced long term survival. No consensus statement has been made and traditionally efforts are usually terminated after 15-30 minutes." The case under discussion seems worthy of the somewhat detailed description given. It is for a young man who survived after 65 minutes after electrical shock (ES) after prolonged high-quality cardiopulmonary resuscitation (CPR), multiple defibrillations, and artificial ventilation without any sequelae. Early start of adequate chest compressions and close adherence to advanced cardiac life support protocols played a vital role in successful CPR.

  5. Factors Associated with Sequelae of Campylobacter and Non-typhoidal Salmonella Infections: A Systematic Review.

    Science.gov (United States)

    Esan, Oluwaseun B; Pearce, Madison; van Hecke, Oliver; Roberts, Nia; Collins, Dylan R J; Violato, Mara; McCarthy, Noel; Perera, Rafael; Fanshawe, Thomas R

    2017-02-01

    Despite the significant global burden of gastroenteritis and resulting sequelae, there is limited evidence on risk factors for sequelae development. We updated and extended previous systematic reviews by assessing the role of antibiotics, proton pump inhibitors (PPI) and symptom severity in the development of sequelae following campylobacteriosis and salmonellosis. We searched four databases, including PubMed, from 1 January 2011 to 29 April 2016. Observational studies reporting sequelae of reactive arthritis (ReA), Reiter's syndrome (RS), irritable bowel syndrome (IBS) and Guillain-Barré syndrome (GBS) following gastroenteritis were included. The primary outcome was incidence of sequelae of interest amongst cases of campylobacteriosis and salmonellosis. A narrative synthesis was conducted where heterogeneity was high. Of the 55 articles included, incidence of ReA (n=37), RS (n=5), IBS (n=12) and GBS (n=9) were reported following campylobacteriosis and salmonellosis. A pooled summary for each sequela was not estimated due to high level of heterogeneity across studies (I2>90%). PPI usage and symptoms were sparsely reported. Three out of seven studies found a statistically significant association between antibiotics usage and development of ReA. Additional primary studies investigating risk modifying factors in sequelae of GI infections are required to enable targeted interventions. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  6. Emotional sequelae of abortion: implications for clinical practice.

    Science.gov (United States)

    Lemkau, J P

    1988-12-01

    Without ambivalence, psychotherapy would be unnecessary; however there is a great deal of ambivalence about abortion so it is a therapy issue. In our society abortion decision are made in an ambivalent environment. Even when a woman makes a free decision to have a legal abortion, an emotional sequelae can ensue. This article reviews literature and relates professional experience about the psychological problems and treatment of women before and after having an abortion. A feeling of relief is the typical reaction to an abortion for the woman. The issues involved in the decision process are the woman's own health and happiness as well as that of her future family. The issues include medical and interpersonal ones and often present a moral crisis. Issues such as education, occupation, and relationships must be considered. Three major types of reactions seem to follow an abortion. The 1st is a positive feeling of happiness and relief. The 2nd and 3rd are negative, one being socially based guilt and the other being individually based guilt. Identifying abortion related issues in psychotherapy is not always easy, since they are no usually directly presented to the therapist. They often manifest themselves as symptoms of other problems. Research suggests that unmarried young women without children have a harder time resolving all the issues involved in making an abortion decision. One effective method of discovering emotional problems is to determine the reasons for delaying an abortion. If a woman is having problems making the decision is must be for an important reason. Just as important is the aftermath of the abortion. Attempts should be made to discover as much information about the procedure itself, the recovery time and any repercussions of the procedure. Neither research nor clinical experience has shown that abortion related psychotherapy is different than other forms of treatment. Griefwork, educational approaches, reviews of the decision making process and

  7. Seroprevalence of campylobacteriosis and relevant post-infectious sequelae.

    Science.gov (United States)

    Zautner, A E; Johann, C; Strubel, A; Busse, C; Tareen, A M; Masanta, W O; Lugert, R; Schmidt-Ott, R; Groß, U

    2014-06-01

    Post-infectious sequelea such as Guillain Barré syndrome (GBS), reactive arthritis (RA), and inflammatory bowel disease (IBD) may arise as a consequence of acute Campylobacter-enteritis (AE). However, reliable seroprevalence data of Campylobacter-associated sequelae has not been established. The objectives of this study were, first, to identify the most specific and sensitive test antigen in an optimized ELISA assay for diagnosing a previous Campylobacter-infection and, second, to compare the prevalence of anti-Campylobacter antibodies in cohorts of healthy blood donors (BD), AE, GBS, RA, and IBD patients with antibodies against known GBS, RA and IBD triggering pathogens. Optimized ELISAs of single and combined Campylobacter-proteins OMP18 and P39 as antigens were prepared and sera from AE, GBS, RA and IBD patients and BD were tested for Campylobcter-specific IgA and IgG antibodies. The results were compared with MIKROGEN™-recomLine Campylobacter IgA/IgG and whole cell lysate-immunoblot. Antibodies specific for Helicobacter pylori, Mycoplasma pneumoniae, Yersinia enterocolitica, and Borrelia afzelii were tested with commercial immunoblots. ROC plot analysis revealed AUC maxima in the combination of OMP18 and P39 for IgA and in the P39-antigen for IgG. As a result, 34-49 % GBS cases, 44-62 % RA cases and 23-40 % IBD cases were associated with Campylobacter-infection. These data show that Campylobcater-seropositivity in these patient groups is significantly higher than other triggering pathogens suggesting that it plays an important role in development of GBS and RA, and supports the hypothesis that recurrent acute campylobacteriosis triggers IBD.

  8. Pharmacological treatment of neurobehavioural sequelae of traumatic brain injury.

    Science.gov (United States)

    Lombardi, F

    2008-01-01

    Neurobehavioural sequelae of traumatic brain injuries require an appropriate/effective pharmacological response in that they represent an important cause of disability. In this field, there is no evidence that reaches the level of a standard: there are guidelines on the use of methylphenidate, donepezil and bromocriptine for the treatment of cognitive disturbances, for the non-use of phenytoin and for the use of beta-blockers for controlling aggressiveness. Resolving a single symptom is not relevant in a rehabilitation project if it is not in the context of a more complex picture of neurobehavioural recovery, in which the positive and negative effects of every therapeutic choice are considered. For example, phenytoin could be used for the positive control of epileptic crises but is not advised since it impedes the recovery of cognitive functions in general. Analogous effects not yet identified may concern benzodiazepine, neuroleptics and other sedatives usually prescribed in cases of cranial trauma. Psychotropic drugs are considered to be able to influence the neuronal plasticity processes. Studies on animals have shown that the administration of D-amphetamine combined with sensorial-motor exercise produces the steady acceleration of motor recovery, which acts as a catalyst to the neurological recovery process. On the other hand, alpha1-NA receptor antagonist drugs produce negative effects; these include clonidine (antihypertension) and haloperidol (neuroleptic). Studies need to be carried out to evaluate the effectiveness of particular drugs. These studies need to focus not only on the disappearance of symptoms but also on the positive and negative effects on overall rehabilitation and on the neurobiological recovery of the patient.

  9. Do severe systemic sequelae of proteinuria modulate the antiproteinuric response to chronic ACE inhibition?

    NARCIS (Netherlands)

    Bos, H; Henning, RH; de Jong, PE; de Zeeuw, D; Navis, G

    2002-01-01

    Background. ACE inhibition exerts an antiproteinuric and renoprotective effect. However, residual proteinuria is often present. As residual proteinuria is associated with a poor renal outcome, identification of its determinants is important. We found previously that the systemic sequelae of proteinu

  10. Chronic pain and other sequelae in long-term breast cancer survivors: Nationwide survey in Denmark

    DEFF Research Database (Denmark)

    Peuckmann, V.; Ekholm, O.; Rasmussen, N.K.

    2008-01-01

    Cooperative Group register, which is representative regarding long-term BCS in Denmark. Assessment: Self-administered questionnaire including questions on sociodemography, chronic pain (>= 6 months), health-related quality Of life (HRQOL) and other sequelae related to breast cancer. Associations...... were radiotherapy and younger age. Future research should therefore prioritize sequelae prevention. (C) 2008 European Federation of Chapters of the International Association for the Study of Pain. Published by Elsevier Ltd. All rights reserved Udgivelsesdato: 2009/5...

  11. Clinical and radiographic sequelae to primary teeth affected by dental trauma: a 9-year retrospective study.

    Science.gov (United States)

    Costa, Vanessa Polina Pereira; Goettems, Marilia Leão; Baldissera, Elaine Zanchin; Bertoldi, Andréa Dâmaso; Torriani, Dione Dias

    2016-08-18

    This retrospective study aimed at determining the predicted risks of clinical and radiographic complications in primary teeth following traumatic dental injuries, according to injury type, severity and child's age. Data were collected from records of children treated at a Dental Trauma Center in Brazil for nine years. Records of 576 children were included; clinical sequelae were assessed in 774 teeth, and radiographic sequelae, in 566 teeth. A total of 408 teeth (52.7%) had clinical sequelae and 185 teeth (32.7%), radiographic sequelae. The type of injury with the highest number of clinical sequelae was the crown-root fracture (86.4%). Clinical sequelae increased with injury severity (p teeth with enamel fracture, and 26.0% (95%CI 14-40) for teeth with enamel dentin fracture as well as enamel dentin pulp fracture. Risk of periapical radiolucency was higher for teeth with enameldentinpulp fracture (61.1% 95%CI 35-82) and those with subluxation (15.8% 95%CI 10-22). Risk of premature loss was 27.3% (95%CI 13-45) for teeth with extrusive luxation, and 10.2% (95%CI 5-17) for those with intrusive luxation. The assessment of predicted risks of sequelae showed that teeth with hard tissue trauma tended to present color change, periapical radiolucency and premature loss, whereas teeth with supporting tissue trauma showed color change, abnormal position, premature loss and periapical radiolucency as the most common sequelae. Knowledge about the predicted risks of complications may help clinicians establish appropriate treatment plans.

  12. Diagnosis of adolescent polycystic ovary syndrome.

    Science.gov (United States)

    Hardy, Tristan S E; Norman, Robert J

    2013-08-01

    Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women of reproductive age and is increasingly recognized as a disorder manifesting in the peripubertal and adolescent period. Diagnosis in the adolescent is difficult due to the high background rate of menstrual irregularity, the high prevalence of polycystic ovarian morphology and hyperandrogenic features in this population. Recent guidelines suggest that menstrual irregularity for over two years, reduced reliance on ultrasound diagnosis of polycystic ovarian morphology, and accurate assessment of hyperandrogenic and metabolic features are suitable strategies for the diagnosis of PCOS in the adolescent. Accurate diagnosis is important given the long-term implications of the disorder, with increasing emphasis on metabolic sequelae.

  13. Enfermedades endocrinas en el adulto mayor

    Directory of Open Access Journals (Sweden)

    B. Carlos García, Dr.

    2013-09-01

    A pesar de la heterogeneidad, múltiple co morbilidad y escasa literatura en que se incluye adultos mayores, se proponen algunas recomendaciones para el tratamiento individual del paciente diabético anciano, se revisan las particularidades del diagnóstico y tratamiento del híper e hipotiroidismo, algunas ideas en relación al manejo de la osteoporosis en la mujer mayor y el hombre anciano. Finalmente se aborda la dificultad diagnóstica del hipogonadismo tardío con las indicaciones y contra indicaciones del uso de testosterona.

  14. [Self-concept level in children with burns sequelae: A comparative study].

    Science.gov (United States)

    Castillo C, Carmen; Santander M, Dolores; Solís F, Fresia

    2015-01-01

    Self-concept is the set of ideas and attitudes that a person has about him/herself. To evaluate whether there are differences in the level of self-concept in children 8-12 years old with and without burns sequelae. To identify predictive variables of self-concept in children with sequelae. A comparative cross-sectional study of self-concept in 109 children with burns sequelae, from 8 to 12 years old, with 109 children without burns sequelae, and of the same age and socioeconomic status. The Piers-Harris self-concept scale is used, which provides a general measurement of self-concept and behavioural, intellectual and school status, appearance, and physical attributes, anxiety, popularity, happiness and satisfaction dimensions. There were no significant differences in the level of general self-concept or their dimensions (P>.05). In the group with burns sequelae, the protective factor was the variable number of sequels was associated with the dimensions of anxiety, popularity, happiness-satisfaction and general self-concept. The location variable emerged as a risk factor for the behavioural dimension. The absence of differences in self-concept between children with burns sequelae and children without them is similar to that reported in the literature. The finding in the risk and protective factors encourages to further research, and perhaps incorporating pre-morbidity and family background. Copyright © 2015 Sociedad Chilena de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved.

  15. Tool for objective quantification of pulmonary sequelae in monitoring of patients with tuberculosis; Ferramenta para quantificacao objetiva de sequelas pulmonares no acompanhamento de pacientes com tuberculose

    Energy Technology Data Exchange (ETDEWEB)

    Giacomini, Guilherme; Alvarez, Matheus; Pina, Diana R. de; Bacchim Neto, Fernando A.; Pereira, Paulo C.M.; Ribeiro, Sergio M.; Miranda, Jose Ricardo de A., E-mail: guigiacomini92@aluno.ibb.unesp.br [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Botucaru, SP (Brazil)

    2014-07-01

    Tuberculosis (TB), caused by Mycobacterium tuberculosis, is an ancient infectious disease that remains a global health problem. Chest radiography is the method commonly employed in assessing the evolution of TB. However, lung damage quantification methods are usually performed on a computerized tomography (CT). This objective quantification is important in the radiological monitoring of the patient by assessing the progression and treatment of TB. However, precise quantification is not feasible by the number of CT examinations necessary due to the high dose subjected to the patient and high cost to the institution. The purpose of this work is to develop a tool to quantify pulmonary sequelae caused by TB through chest X-rays. Aiming the proposed objective, a computational algorithm was developed, creating a three-dimensional representation of the lungs, with regions of dilated sequelae inside. It also made the quantification of pulmonary sequelae of these patients through CT scans performed in upcoming dates, minimizing the differences in disease progression. The measurements from the two methods were compared with results suggest that the effectiveness and applicability of the developed tool, allowing lower doses radiological monitoring of the patient during treatment.

  16. Clinical Study on Kidney-Nourishing and Governor Vessel-Regulating Acupuncture Therapy for Apoplexy Sequela

    Institute of Scientific and Technical Information of China (English)

    LI Yan; PANG Yong; ZOU Zhuo-cheng; XIAO Yuan-chun

    2007-01-01

    To observe the clinical efficacy of kidney-nourishing and governor vessel-regulating therapy for apoplexy sequela.Methods:Sixty subjects were equally randomized into observation group and control group,and respectively treated for 35 days.The scores of survival quality,interleukin-6(IL-6),interleukin-8(IL-8)and tumor necrosis factor (TNF) were measured,and the clinical efficacy were compared between two groups.Results and Conclusion:After treatment.all the observational items were improved,with better results in observation group than in control group.This therapy has better effects than regular method in the treatment of apoplexy sequela.

  17. Left atrial wall dissection: a rare sequela of native-valve endocarditis.

    Science.gov (United States)

    Saad, Marwan; Isbitan, Ahmad; Roushdy, Alaa; Shamoon, Fayez

    2015-04-01

    Left atrial wall dissection is a rare condition; most cases are iatrogenic after mitral valve surgery. A few have been reported as sequelae of blunt chest trauma, acute myocardial infarction, and invasive cardiac procedures. On occasion, infective endocarditis causes left atrial wall dissection. We report a highly unusual case in which a 41-year-old man presented with native mitral valve infective endocarditis that had caused left atrial free-wall dissection. Although our patient died within an hour of presentation, we obtained what we consider to be a definitive diagnosis of a rare sequela, documented by transthoracic and transesophageal echocardiography.

  18. Magnetic resonance imaging of sequelae of central pontine myelinolysis in chronic alcohol abusers

    Energy Technology Data Exchange (ETDEWEB)

    Uchino, Akira; Kudo, Sho [Department of Radiology, Saga Medical School, 5-1-1 Nabeshima, 849-8501, Saga (Japan); Yuzuriha, Takefumi; Murakami, Masaru; Endoh, Koichi; Hiejima, Shigeto; Koga, Hiroshi [Center for Emotional and Behavional Disorders, Hizen National Hospital, 160 Mitsu, Higashisefuri, Kanzaki, 842-0192, Saga (Japan)

    2003-12-01

    Central pontine myelinolysis (CPM) is one of the serious neurological complications of alcoholism. This study evaluated magnetic resonance images of sequelae of CPM. Approximately 600 alcoholic patients were examined by a 1.0-T magnetic resonance imaging device, and 11 patients were retrospectively found to have a central pontine lesion, a presumed sequela of CPM. The lesions had various shapes and most were cavitary. In 3 of the 11 patients bilateral symmetrical oval lesions were faintly visible in the middle cerebellar peduncles. These middle cerebellar peduncular lesions were diagnosed as having Wallerian degeneration of the pontocerebellar tract secondary to CPM. (orig.)

  19. Bony fusion of the maxilla and mandible as a sequelae of noma: A rare case report.

    Science.gov (United States)

    Bagewadi, Shivanand B; Awasthi, Ujjwala Rastogi; Mody, Bharat M; Suma, Gundareddy N; Garg, Shruti

    2015-09-01

    Noma is a gangrenous disease of the orofacial region that leads to severe facial tissue destruction and is a significant cause of death among children. With the advent of modern antibiotics and improved nutrition, children with noma may survive into adulthood, but must face the challenge of undergoing repair of the sequelae of noma. This report describes a case of bony fusion of the maxilla and mandible in a 28-year-old female patient, which was a sequelae of a childhood case of noma.

  20. Bony fusion of the maxilla and mandible as a sequelae of noma: A rare case report

    Energy Technology Data Exchange (ETDEWEB)

    Bagewadi, Shivanand B.; Awasthi, Ujjwala Rastogi; Mody, Bharat M.; Suma, Gundareddy N.; Garg, Shruti [Dept. of Medicine and Radiology, ITS Center for Dental Studies and Research, Ghaziabad, Uttar Pradesh (Korea, Republic of)

    2015-09-15

    Noma is a gangrenous disease of the orofacial region that leads to severe facial tissue destruction and is a significant cause of death among children. With the advent of modern antibiotics and improved nutrition, children with noma may survive into adulthood, but must face the challenge of undergoing repair of the sequelae of noma. This report describes a case of bony fusion of the maxilla and mandible in a 28-year-old female patient, which was a sequelae of a childhood case of noma.

  1. A 5-year longitudinal study of fatigue in patients with late-onset sequelae of poliomyelitis.

    NARCIS (Netherlands)

    Tersteeg, I.M.; Koopman, F.S.; Stolwijk-Swuste, J.M.; Beelen, A.; Nollet, F.

    2011-01-01

    Objectives: To study the severity and 5-year course of fatigue in patients with late-onset sequelae of poliomyelitis (LOSP) and to identify physical and psychosocial determinants of fatigue. Design: Prospective cohort study with 5 measurements over 5 years. Setting: University hospital.Participants:

  2. Endocrine Disorders in Childhood: A Selective Survey of Intellectual and Educational Sequelae.

    Science.gov (United States)

    Sandberg, David E.; Barrick, Christopher

    1995-01-01

    Examines intellectual and educational sequelae of selected endocrine systems and the psychosocial impact of their medical conditions. Many conditions are named including: Growth Hormone Deficiency, Turner Syndrome, Precocious Puberty, Klinefelters Syndrome, Congenital Hypothyroidism, and Insulin-Dependent Diabetes Mellitus. Gives psychoeducational…

  3. "Comparison of recovery rate and sequelae of various location of ventilation tube insertion "

    Directory of Open Access Journals (Sweden)

    Abbas Safavi Naini S

    2002-08-01

    Full Text Available Ventilation tube (VT insertion is the most common otologic operations performed in children, which has great importance in recovery and prevention of hearing loss in children with Eustachian tube dysfunction in critical ages of growth development. The location of the VT insertion varies in different studies; the differences are in recovery rates and sequelae of VT insertion. This study is performed to compare results of various locations of VT insertion in hearing recovery rate and postoperative sequelae in the Booali Hospital from 1999 to 2000 (one-year period. This investigation is a clinical trial in 34 patients with Eustachian tube dysfunction; cases were selected according to history, otologic examination, adenoid radiography, audiometry (SRT, PTA-GAP and tympanometry. The operating time consumed in the VT insertion and postoperative sequelae were recorded. Recovery rates of SAR and PTA-Gap were 25.14 dB and 18.41 dB in anterosuperior (AS versus 18/67 dB and 14/85 dB in anteroinferior (AT VT insertion respectively. Obstruction and otorrhea after VT insertion were 0, 4 and 13, 11 in AS and AI, respectively. Time difference in the AS versus AI was not significant. The assessment confirmed that anterosuperior VT insertion has better hearing recovery rate and lower postoperative sequelae.

  4. Predicting sequelae and death after bacterial meningitis in childhood: A systematic review of prognostic studies

    NARCIS (Netherlands)

    R.C.J. de Jonge; A.M. van Furth; M. Wassenaar; R.J.B.J. Gemke; C.B. Terwee

    2010-01-01

    Background: Bacterial meningitis (BM) is a severe infection responsible for high mortality and disabling sequelae. Early identification of patients at high risk of these outcomes is necessary to prevent their occurrence by adequate treatment as much as possible. For this reason, several prognostic m

  5. Endocrine Disorders in Childhood: A Selective Survey of Intellectual and Educational Sequelae.

    Science.gov (United States)

    Sandberg, David E.; Barrick, Christopher

    1995-01-01

    Examines intellectual and educational sequelae of selected endocrine systems and the psychosocial impact of their medical conditions. Many conditions are named including: Growth Hormone Deficiency, Turner Syndrome, Precocious Puberty, Klinefelters Syndrome, Congenital Hypothyroidism, and Insulin-Dependent Diabetes Mellitus. Gives psychoeducational…

  6. The isolated burned palm in children : Epidemiology and long-term sequelae

    NARCIS (Netherlands)

    Barret, JP; Desai, MH; Herndon, DN

    The isolated burn of the palm is a typical injury in young children. Positioning and splinting in small hands is difficult, and long-term sequelae of these injuries are not uncommon. The objective of the present study was to assess the outcome of palm burns and to identify the risk factors for

  7. PROTOCOL FOR THE PREVENTION AND TREATMENT OF ORAL SEQUELAE RESULTING FROM HEAD AND NECK RADIATION-THERAPY

    NARCIS (Netherlands)

    JANSMA, J; VISSINK, A; SPIJKERVET, FKL; ROODENBURG, JLN; PANDERS, AK; VERMEY, A; SZABO, BG; SGRAVENMADE, EJ

    1992-01-01

    In addition to the desired antitumor effects, head and neck radiation therapy induces damage in normal tissues that may result in oral sequelae such as mucositis, hyposalivation, radiation caries, taste loss, trismus, soft-tissue necrosis, and osteoradionecrosis. These sequelae may be dose-limiting

  8. Dressing-related trauma: clinical sequelae and resource utilization in a UK setting

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    Charlesworth B

    2014-04-01

    Full Text Available Bruce Charlesworth,1 Claire Pilling,1 Paul Chadwick,2 Martyn Butcher31Adelphi Values, Macclesfield, 2Salford Royal Foundation Trust, Salford, 3Northern Devon Healthcare Trust, Devon, UKBackground: Dressings are the mainstay of wound care management; however, adherence of the dressing to the wound or periwound skin is common and can lead to dressing-related pain and trauma. Dressing-related trauma is recognized as a clinical and economic burden to patients and health care providers. This study was conducted to garner expert opinion on clinical sequelae and resource use associated with dressing-related trauma in a UK setting.Methods: This was an exploratory study with two phases: qualitative pilot interviews with six wound care specialists to explore dressing-related trauma concepts, sequelae, and resource utilization; and online quantitative research with 30 wound care specialists to validate and quantify the concepts, sequelae, and resource utilization explored in the first phase of the study. Data were collected on mean health care professional time, material costs, pharmaceutical costs, and inpatient management per sequela occurrence until resolution. Data were analyzed to give total costs per sequela and concept occurrence.Results: The results demonstrate that dressing-related trauma is a clinically relevant concept. The main types of dressing-related trauma concepts included skin reactions, adherence to the wound, skin stripping, maceration, drying, and plugging of the wound. These were the foundation for a number of clinical sequelae, including wound enlargement, increased exudate, bleeding, infection, pain, itching/excoriation, edema, dermatitis, inflammation, and anxiety. Mean total costs range from £56 to £175 for the complete onward management of each occurrence of the six main concepts.Conclusion: These results provide insight into the hidden costs of dressing-related trauma in a UK setting. This research successfully conceptualized

  9. Long-term sequelae of chikungunya virus disease: A systematic review.

    Science.gov (United States)

    van Aalst, Mariëlle; Nelen, Charlotte Marieke; Goorhuis, Abraham; Stijnis, Cornelis; Grobusch, Martin Peter

    The acute phase of chikungunya is well documented; less so are its long-term effects. This systematic literature review provides an overview of the currently available data. We performed an electronic search in PubMed/Medline and checked reference lists. We included studies in English on long-term sequelae of chikungunya in adults and on long-term sequelae of congenital infection from 2000 to 2016. Case reports, reviews and studies with a follow-up shorter than 6 weeks were excluded. In total, 37 studies were included; with follow-up periods ranging from 1.5 to 72 months. Most studies were questionnaire-based studies only, in which clinical diagnoses such as arthritis, alopecia and depression were mostly recorded without professional verification. Persisting arthralgia/arthritis (arthralgia/joint stiffness plus joint swelling) was the most frequent problem encountered. Further frequently mentioned sequelae were alopecia and depression. Quality of life was reduced in many for months to years after the acute phase of chikungunya. Female gender, older age, some co-morbidities and the severity of the acute phase were associated with persistent arthralgia. Congenital infection was associated with neurocognitive dysfunctioning in early childhood. Chikungunya leads to (self-perceived) long-term sequelae in a considerable proportion of patients, impacting significantly on quality of life. Long-term chikungunya sequelae must be taken into account when dealing with this disease because of its important effect on public and individual health. Prospective large-scale, long-term studies with objective assessment of signs and symptoms attributed to the disease are needed to optimally quantify and qualify these problems. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Prevalência de sequelas auditivas pós meningite piogênica em crianças Prevalence of auditory sequelae after pyogenic meningitis in children

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    Luzia Poliana Anjos da Silva

    2009-01-01

    Full Text Available OBJETIVO: Analisar a prevalência de déficit auditivo e caracterizar as principais sequelas auditivas e neurológicas pós-meningite, correlacionando o tipo de antibiótico utilizado durante o período de internação e a frequência de surdez, além do tipo de meningite mais prevalente como causa de déficit auditivo. MÉTODOS: Trata-se de um estudo de coorte transversal. Foram enviadas 289 cartas para os responsáveis pelas crianças que apresentaram meningite piogênica entre 28 dias e 24 meses, admitidas no Hospital Couto Maia (HC Maia entre janeiro de 2002 a dezembro de 2003. A amostra foi constituída por 55 crianças que sobreviveram com ou sem sequelas evidentes, que compareceram para as avaliações audiológica e neurológica. Foi realizada avaliação audiológica completa, incluindo a bateria subjetiva e objetiva de avaliação, com utilização de instrumentos validados para investigação da audição da criança. RESULTADOS: A faixa etária, no momento da avaliação audiológica, variou de dois a cinco anos. A deficiência auditiva foi encontrada em 29% da amostra, sendo a maioria do tipo neurossensorial, bilateral e de grau profundo. As principais sequelas neurológicas encontradas foram epilepsia, hemiparesia, hidrocefalia, disfasia e hiperatividade. CONCLUSÃO: Os resultados destacam a necessidade de monitoramento audiológico e acompanhamento neurológico nas crianças com história prévia de meningite piogênica, especialmente aquelas infectadas em idade precoce, buscando, desta forma, detectar as possíveis alterações auditivas e intervir o mais precocemente possível, por meio de intervenção especializada, protetização e reabilitação da linguagem oral.PURPOSE: To analyze the prevalence of hearing impairment and to characterize the main auditory and neurological sequelae after meningitis, correlating the type of antibiotic used during the hospitali66zation period and the frequency of deafness, as well as the most

  11. [Sudden death of a young man as late sequelae complicating a pediatric disease: About a case].

    Science.gov (United States)

    Pierry, Clémence; Franchet, Camille; Tuchtan-Torrents, Lucile; Macon, Céline; Torrents, Julia; Capuani, Caroline; Piercecchi-Marti, Marie-Dominique

    2017-04-01

    In France, sudden death is responsible every year for 40,000 deaths. The most frequent etiology is cardiac disease. Atheromatous-related pathology is the most common etiology beyond 35, but cardiomyopathies and channelopathies are responsible for a significant number of deaths in young adults. Some acquired disorders can also cause sudden cardiac death. We report the case of a 17-year-old man who died suddenly after sport. Autopsy and pathological study found multiple giant coronary aneurysms. Thrombosis and fibrous scar of myocardial ischemic events were observed. These lesions were in favor of late sequelae of Kawasaki disease. Kawasaki disease is a rare but not exceptional cause of sudden cardiac death in young adults. In the lack of known clinical history, some aspects, even not specific, should evoke this diagnosis. Even in front of apparent good clinical tolerance, these sequelae require appropriate follow-up because of a significant risk of sudden death.

  12. Stroke with neuropsychiatric sequelae after cannabis use in a man: a case report

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    Giroud Maurice

    2011-06-01

    Full Text Available Abstract Introduction The outcome of cerebral ischemic stroke associated with cannabis use is usually favorable. Here we report the first case of cannabis-related stroke followed by neuropsychiatric sequelae. Case presentation A 24-year-old Caucasian man was discovered in a deeply comatose non-reactive state after cannabis use. A magnetic resonance imaging scan of his brain showed bilateral multiple ischemic infarcts. The patient remained deeply comatose for four days, after which time he developed other behavioral impairments and recurrent seizures. Conclusion Stroke related to cannabis use can be followed by severe neuropsychiatric sequelae. Concomitant alcohol intoxication is essential neither to the occurrence of this neurologic event nor to its severity.

  13. The functional sequelae of sacrococcygeal teratoma: a longitudinal and cross-sectional follow-up study.

    Science.gov (United States)

    Cozzi, Francesco; Schiavetti, Amalia; Zani, Augusto; Spagnol, Lorna; Totonelli, Giorgia; Cozzi, Denis A

    2008-04-01

    The purpose of the study was to determine clinical manifestations, prevalence, and natural history of functional sequelae in patients operated on for sacrococcygeal teratoma (SCT) during infancy. The medical records of 18 infants operated on for SCT were reviewed. Data recorded during admission and during routine outpatient appointments were analyzed. Moreover, 13 surviving patients (mean age, 25 years) and 65 age- and sex-matched controls were evaluated at a special outpatient clinic. Seven adult patients and 25 controls presented with one or more functional disorders including abdominal pain, constipation, diarrhea, soiling, enuresis, urinary frequency, urinary stress incontinence, and urinary straining. In 7 of 8 symptomatic children, one or more functional disorders disappeared during adult life. In comparison with controls, adult patients had a nonsignificant higher prevalence of each individual dysfunction. Sequelae of SCT tend to improve with time, and the disorders reported are relatively common complaints in the general population.

  14. Contact radiotherapy of cutaneous hemangiomas: therapeutic effects and radiation sequelae in 818 patients.

    Science.gov (United States)

    Braun-Falco, O; Schultze, U; Meinhof, W; Goldschmidt, H

    1975-10-29

    The paper presents statistical data on the therapeutic effects and radiation sequelae following Chaoul contact therapy of 818 cutaneous hemangiomas treated between 1938 and 1952. 73.3% of all irradiated hemangiomas showed initial improvement but complete involution with an excellent cosmetic result was observed in only 50% of lesions 5 years after treatment. During the same period of time, more than one-third of all patients developed mild to moderate cutaneous radiation sequelae (hyper- or hypopigmentation and telangiectases, rarely atrophy). The high incidence of late radiation effects is probably relation to the high total doses administered in this series of patients, the very short intervals between treatments and the age of the patients. Other radiation radiation hazards are also discussed. Since large studies have proven conclusively that spontaneous involution occurs in 95% of hemangiomas after several years, indications for radiotherapy of hemangiomas are extremely limited.

  15. Electrical impedance spectroscopy as electrical biopsy for monitoring radiation sequelae of intestine in rats.

    Science.gov (United States)

    Chao, Pei-Ju; Huang, Eng-Yen; Cheng, Kuo-Sheng; Huang, Yu-Jie

    2013-01-01

    Electrical impedance is one of the most frequently used parameters for characterizing material properties. The resistive and capacitive characteristics of tissue may be revealed by electrical impedance spectroscopy (EIS) as electrical biopsy. This technique could be used to monitor the sequelae after irradiation. In this study, rat intestinal tissues after irradiation were assessed by EIS system based on commercially available integrated circuits. The EIS results were fitted to a resistor-capacitor circuit model to determine the electrical properties of the tissue. The variations in the electrical characteristics of the tissue were compared to radiation injury score (RIS) by morphological and histological findings. The electrical properties, based on receiver operation curve (ROC) analysis, strongly reflected the histological changes with excellent diagnosis performance. The results of this study suggest that electrical biopsy reflects histological changes after irradiation. This approach may significantly augment the evaluation of tissue after irradiation. It could provide rapid results for decision making in monitoring radiation sequelae prospectively.

  16. Electrical Impedance Spectroscopy as Electrical Biopsy for Monitoring Radiation Sequelae of Intestine in Rats

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    Pei-Ju Chao

    2013-01-01

    Full Text Available Electrical impedance is one of the most frequently used parameters for characterizing material properties. The resistive and capacitive characteristics of tissue may be revealed by electrical impedance spectroscopy (EIS as electrical biopsy. This technique could be used to monitor the sequelae after irradiation. In this study, rat intestinal tissues after irradiation were assessed by EIS system based on commercially available integrated circuits. The EIS results were fitted to a resistor-capacitor circuit model to determine the electrical properties of the tissue. The variations in the electrical characteristics of the tissue were compared to radiation injury score (RIS by morphological and histological findings. The electrical properties, based on receiver operation curve (ROC analysis, strongly reflected the histological changes with excellent diagnosis performance. The results of this study suggest that electrical biopsy reflects histological changes after irradiation. This approach may significantly augment the evaluation of tissue after irradiation. It could provide rapid results for decision making in monitoring radiation sequelae prospectively.

  17. Predicting sequelae and death after bacterial meningitis in childhood: A systematic review of prognostic studies

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    Gemke Reinoud JBJ

    2010-08-01

    Full Text Available Abstract Background Bacterial meningitis (BM is a severe infection responsible for high mortality and disabling sequelae. Early identification of patients at high risk of these outcomes is necessary to prevent their occurrence by adequate treatment as much as possible. For this reason, several prognostic models have been developed. The objective of this study is to summarize the evidence regarding prognostic factors predicting death or sequelae due to BM in children 0-18 years of age. Methods A search in MEDLINE and EMBASE was conducted to identify prognostic studies on risk factors for mortality and sequelae after BM in children. Selection of abstracts, full-text articles and assessment of methodological quality using the QUIPS checklist was performed by two reviewers independently. Data on prognostic factors per outcome were summarized. Results Of the 31 studies identified, 15 were of moderate to high quality. Due to substantial heterogeneity in study characteristics and evaluated prognostic factors, no quantitative analysis was performed. Prognostic factors found to be statistically significant in more than one study of moderate or high quality are: complaints >48 hours before admission, coma/impaired consciousness, (prolonged duration of seizures, (prolonged fever, shock, peripheral circulatory failure, respiratory distress, absence of petechiae, causative pathogen Streptococcus pneumoniae, young age, male gender, several cerebrospinal fluid (CSF parameters and white blood cell (WBC count. Conclusions Although several important prognostic factors for the prediction of mortality or sequelae after BM were identified, the inability to perform a pooled analysis makes the exact (independent predictive value of these factors uncertain. This emphasizes the need for additional well-conducted prognostic studies.

  18. The Clinical Study on 34 Admission Patients due to Sequela of Traffic Accident

    OpenAIRE

    No, Bu-Rae; Lee, Eun-Yong

    2006-01-01

    Objectives : The purpose of this study was to investigate the clinical progress of patients diagnosed as sequela of traffic accident. Methods : We studied 34 cases who were admitted in Semyung University Oriental Hospital from 1st, January, 2005 to the 31st, December, 2005. And we came to some conclusion about clinical tendencies as follows. Results and Conclusions : 1. Women had occupied more than men, and 14 persons in 20th were the most distribution of age. 2. In distribution o...

  19. Severe neurological sequelae and behaviour problems after cerebral malaria in Ugandan children

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    Tugumisirize Joshua

    2010-04-01

    Full Text Available Abstract Background Cerebral malaria is the most severe neurological complication of falciparum malaria and a leading cause of death and neuro-disability in sub-Saharan Africa. This study aimed to describe functional deficits and behaviour problems in children who survived cerebral malaria with severe neurological sequelae and identify patterns of brain injury. Findings Records of children attending a specialist child neurology clinic in Uganda with severe neurological sequelae following cerebral malaria between January 2007 and December 2008 were examined to describe deficits in gross motor function, speech, vision and hearing, behaviour problems or epilepsy. Deficits were classified according to the time of development and whether their distribution suggested a focal or generalized injury. Any resolution during the observation period was also documented. Thirty children with probable exposure to cerebral malaria attended the clinic. Referral information was inadequate to exclude other diagnoses in 7 children and these were excluded. In the remaining 23 patients, the commonest severe deficits were spastic motor weakness (14, loss of speech (14, hearing deficit (9, behaviour problems (11, epilepsy (12, blindness (12 and severe cognitive impairment (9. Behaviour problems included hyperactivity, impulsiveness and inattentiveness as in attention deficit hyperactivity disorder (ADHD and conduct disorders with aggressive, self injurious or destructive behaviour. Two patterns were observed; a immediate onset deficits present on discharge and b late onset deficits. Some deficits e.g. blindness, resolved within 6 months while others e.g. speech, showed little improvement over the 6-months follow-up. Conclusions In addition to previously described neurological and cognitive sequelae, severe behaviour problems may follow cerebral malaria in children. The observed differences in patterns of sequelae may be due to different pathogenic mechanisms, brain

  20. Acupuncture for sequelae of Bell's palsy: a randomized controlled trial protocol

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    Kim Yong-Suk

    2011-03-01

    Full Text Available Abstract Objective Incomplete recovery from facial palsy has a long-term impact on the quality of life, and medical options for the sequelae of Bell's palsy are limited. Invasive treatments and physiotherapy have been employed to relieve symptoms, but there is limited clinical evidence for their effectiveness. Acupuncture is widely used on Bell's palsy patients in East Asia, but there is insufficient evidence for its effectiveness on Bell's palsy sequelae. The objective is to evaluate the efficacy and safety of acupuncture in patients with sequelae of Bell's palsy. Method/Design This study consists of a randomized controlled trial with two parallel arms: an acupuncture group and a waitlist group. The acupuncture group will receive acupuncture treatment three times per week for a total of 24 sessions over 8 weeks. Participants in the waitlist group will not receive any acupuncture treatments during this 8 week period, but they will participate in the evaluations of symptoms at the start of the study, at 5 weeks and at 8 weeks after randomization, at which point the same treatment as the acupuncture group will be provided. The primary outcome will be analyzed by the change in the Facial Disability Index (FDI from baseline to week eight. The secondary outcome measures will include FDI from baseline to week five, House-Brackmann Grade, lip mobility, and stiffness scales. Trial registration Current Controlled-Trials ISRCTN43104115; registration date: 06 July 2010; the date of the first patient's randomization: 04 August 2010

  1. Sequelae of foodborne illness caused by 5 pathogens, Australia, circa 2010.

    Science.gov (United States)

    Ford, Laura; Kirk, Martyn; Glass, Kathryn; Hall, Gillian

    2014-11-01

    In Australia circa 2010, 4.1 million (90% credible interval [CrI] 2.3-6.4 million) episodes of foodborne gastroenteritis occurred, many of which might have resulted in sequelae. We estimated the number of illnesses, hospitalizations, and deaths from Guillain-Barré syndrome, hemolytic uremic syndrome, irritable bowel syndrome, and reactive arthritis that were associated with contaminated food in Australia. Data from published studies, hospital records, and mortality reports were combined with multipliers to adjust for different transmission routes. We used Monte Carlo simulation to estimate median estimates and 90% CrIs. In Australia, circa 2010, we estimated that 35,840 (90% CrI 25,000-54,000) illnesses, 1,080 (90% CrI 700-1,600) hospitalizations, and 10 (90% CrI 5-14) deaths occurred from foodborne gastroenteritis-associated sequelae. Campylobacter spp. infection was responsible for 80% of incident cases. Reducing the incidence of campylobacteriosis and other foodborne diseases would minimize the health effects of sequelae.

  2. The Effects of Acupuncture on Peripheral Facial Palsy Sequelae after 20 Years via Electromyography.

    Science.gov (United States)

    Fabrin, Saulo; Soares, Nayara; Regalo, Simone Cecilio Hallak; Verri, Edson Donizetti

    2015-10-01

    This research used electromyography to evaluate the effects of acupuncture on facial palsy peripheral sequelae. The 44-year-old woman who participated in this study presented sequelae resulting from 20 years of peripheral facial nerve palsy (FNP) on the right side and synkinesis in the left eye. In electromyography, the electrodes were positioned on the motor points over the orbicularis oris and the orbicularis oculi muscles to establish myofunctional feedback prior to and after rehabilitation, which consisted of 20-minute sessions of acupuncture once per week for 20 weeks: using manual stimulation at acupoints Yintang, LR3, GB21, CV17, ST2, ST3, ST6, ST7, GB2, and SI19; and Tou-Kuang-Min and ST4 using electrical stimulation with a 4-Hz pulsed current. The subjective pain intensities were recorded. The root-mean-square (RMS) electromyographic comparative analysis showed greater activation and recruitment of muscle fibers on the right side and a reduced overload on the left side, which promoted a functional evolution of movements and a positive response in the stomatognathic system. Acupuncture associated with electrical stimulation reversed the peripheral facial paralysis in a short time. Severe sequelae were minimized due to the balance of muscle activation in response to the electrical stimulation provided by the acupuncture needles. Copyright © 2015. Published by Elsevier B.V.

  3. Elevated levels of circulating thyroid hormone do not cause the medical sequelae of hyperthyroidism.

    Science.gov (United States)

    Kelly, Tammas; Denmark, Lawrence; Lieberman, Daniel Z

    2016-11-03

    Clinicians have been reluctant to use high dose thyroid (HDT) to treat affective disorders because high circulating levels of thyroid hormone have traditionally been equated with hyperthyroidism, and understood as the cause of the medical sequelae of hyperthyroidism, such as osteoporosis and cardiac abnormalities. This conclusion is not supported by (HDT) research. A literature review of research related to the morbidity and mortality of HDT treatment was performed. There exists a large body of research involving the use of HDT treatment to prevent the recurrence of differentiated thyroid cancer and to treat affective disorders. A review of this literature finds a lack of support for HDT as a cause of osteoporosis, nor is there support for an increase in morbidity or mortality associated with HDT. This finding contrasts with the well-established morbidity and mortality associated with Graves' disease, thyroiditis, and other endogenous forms of hyperthyroidism. The lack of evidence that exogenous HDT causes osteoporosis, cardiac abnormalities or increases mortality compared with the significant morbidity and mortality of hyperthyroidism requires an alternative cause for the medical sequelae of hyperthyroidism. One possibility is an autoimmune mechanism. High circulating levels of thyroid hormone is not the cause of the sequela of hyperthyroidism. The reluctance to using high dose thyroid is unwarranted. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. IgA modulates respiratory dysfunction as a sequela to pulmonary chlamydial infection as neonates.

    Science.gov (United States)

    Lanka, Gopala Krishna Koundinya; Yu, Jieh-Juen; Gong, Siqi; Gupta, Rishein; Mustafa, Shamimunisa B; Murthy, Ashlesh K; Zhong, Guangming; Chambers, James P; Guentzel, M Neal; Arulanandam, Bernard P

    2016-04-01

    Neonatal Chlamydia lung infections are associated with serious sequelae such as asthma and airway hyper-reactivity in children and adults. Our previous studies demonstrated the importance of Th-1 type cytokines, IL-12 and IFN-γ in protection against neonatal pulmonary chlamydial challenge; however, the role of the humoral arm of defense has not been elucidated. We hypothesized that B-cells and IgA, the major mucosal antibody, play a protective role in newborns against development of later life respiratory sequelae to Chlamydia infection. Our studies using neonatal mice revealed that all WT and IgA-deficient (IgA(-/-)) animals survived a sublethal pulmonary Chlamydia muridarum challenge at one day after birth with similar reduction in bacterial burdens over time. In contrast, all B-cell-deficient (μMT) mice succumbed to infection at the same challenge dose correlating to failure to control bacterial burdens in the lungs. Although IgA may not be important for bacterial clearance, we observed IgA(-/-) mice displayed greater respiratory dysfunction 5 weeks post challenge. Specifically, comparative respiratory functional analyses revealed a significant shift upward in P-V loops, and higher dynamic resistance in IgA(-/-) animals. This study provides insight(s) into the protective role of IgA in neonates against pulmonary chlamydial infection induced respiratory pathological sequelae observed later in life.

  5. Sequelas bucais da radioterapia de cabeça e pescoço Oral sequelae of head and neck radiotherapy

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    Daniel Antunes Freitas

    2011-12-01

    Full Text Available TEMA: cirurgia, radioterapia e quimioterapia são as modalidades terapêuticas usadas no tratamento de câncer bucal. Podem ser usadas isoladas ou conjuntamente. Radiação ionizante causa lesões nos tecidos normais localizados no campo de radiação. Isto se torna particularmente evidente nas regiões de cabeça, uma área complexa composta de várias estruturas diferentes que respondem diferentemente à radiação. As seqüelas orais resultantes podem causar problemas substanciais durante e depois da terapia de radiação e são os maiores fatores de determinação na qualidade de vida dos pacientes. Dentre as complicações da radioterapia estão a xerostomia, osteorradionecrose, mucosite e candidose. OBJETIVO: apresentar aos profissionais de saúde uma reflexão sobre as questões pertinentes às sequelas bucais da radioterapia de cabeça e pescoço. CONCLUSÃO: o acompanhamento odontológico sistemático pode minimizar os efeitos da radiação sobre os tecidos da cavidade bucal.BACKGROUND: surgery, radiotherapy and chemotherapy are therapeutic modalities used in the treatment of oral cancer. They can be used separately or in combination. Ionizing irradiation causes damage to normal tissues located at the radiation field. This becomes particularly evident in the head and neck region, a complex area composed of several dissimilar structures that respond differently to radiation. The resulting oral sequelae may cause substantial problems during and after radiation therapy and are major factors in determining the patient's quality of life. Xerostomia, osteoradionecrosis, mucositis and candidosis are some of radiotherapy's complications. PURPOSE: introduce health professionals to reflect on issues relevant to oral sequelae of head and neck radiotherapy. CONCLUSION: regular dental follow-up may reduce the effects of radiation in the tissues of the oral cavity.

  6. Family-Based Treatment for Adolescent Anorexia Nervosa: A Promising Approach?

    Science.gov (United States)

    Le Grange, Daniel

    2004-01-01

    Despite the fact that anorexia nervosa is a debilitating disorder with serious psychological and medical sequelae, few psychological treatments have been studied. Of these, interventions that involve the parents of the adolescent have proved to be most promising. This is especially true for those cases with a short duration of illness (less than 3…

  7. A simple bracing technique to correct kinking of arterial branches to avoid ischemic sequelae during neurovascular surgery

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    Yasushi Motoyama

    2016-01-01

    Conclusion: The insertion of prostheses with fibrin glue into the crotch of a kinked artery for repair is considered a simple and useful method for correcting a kinked artery that avoids ischemic sequelae.

  8. Neurological images and the predictors for neurological sequelae of epidemic herpangina/hand-foot-mouth disease with encephalomyelitis.

    Science.gov (United States)

    Tsai, Jeng-Dau; Kuo, Hung-Tsung; Chen, Shan-Ming; Lue, Ko-Huang; Sheu, Ji-Nan

    2014-04-01

    Since 1998 in Taiwan, enterovirus (EV) 71 epidemics have caused encephalomyelitis and placed a significant burden on parents and physicians. In this study, we present clinical manifestations, magnetic resonance (MR) imaging findings, and neurological sequelae on epidemic EV-infected patients with encephalomyelitis. Of the 46 patients, 14 patients presented with neurological sequelae; of them, 3 patients suffered from complications of mental regression. Predictors of unfavorable neurological sequelae were myoclonic jerks (> 4 times/night) and pleocytosis (167/μL) of the cerebrospinal fluid (CSF). Results from viral culture and MR imaging indicated that positive identification of EV71 infection was associated significantly with lesions on MR imaging. Our results show that hand-foot-mouth disease carries a higher risk of encephalomyelitis and that frequent myoclonic jerks and pleocytosis of the CSF are risk factors for subsequent neurological sequelae. Positive identification of EV71 might be useful as a predictor of lesions in MR imaging.

  9. In-hospital outcomes and delayed neurologic sequelae of seizure-related endosulfan poisoning.

    Science.gov (United States)

    Moon, J M; Chun, B J; Lee, S D

    2017-07-29

    This study investigated the predictive factors for progression from seizure-related endosulfan poisoning to status epilepticus (SE) and refractory SE (RSE). This study also investigated delayed neurologic sequelae in seizure-related endosulfan poisoning. This retrospective, observational case series consisted of 73 patients who developed at least one seizure after endosulfan ingestion. The progression rates from seizure-related endosulfan poisoning to SE and from SE-related endosulfan poisoning to RSE were 78.1% and 54.4%, respectively. The SE and RSE fatality rates were 19.2% and 41.9%, respectively. No patients reported the development of delayed neurological sequelae at least six months after discharge. Glasgow coma scale (GCS) score were identified as an independent factor for progression from seizure-related endosulfan poisoning to SE and from SE-related endosulfan poisoning to RSE. Lorazepam administration was independently associated with preventing progression from SE-related endosulfan poisoning to RSE. Seizure-related endosulfan poisoning had higher progression rates to SE and RSE and higher fatality rates than other drug-induced seizures. However, delayed neurologic sequelae after discharge were not demonstrated. Due to the high progression rates from seizure-related endosulfan poisoning to SE and RSE and the absence of an established treatment for SE-related endosulfan poisoning, physicians should aggressively treat patients who experience a seizure after endosulfan poisoning and who present with decreased GCS score. Lorazepam should be considered a first-line anti-epileptic drug for controlling seizures in patients with endosulfan poisoning. Copyright © 2017 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

  10. Long-term neurological sequelae of hemolytic-uremic syndrome: a preliminary report.

    Science.gov (United States)

    Qamar, I U; Ohali, M; MacGregor, D L; Wasson, C; Krekewich, K; Marcovitch, S; Arbus, G S

    1996-08-01

    Seven patients with hemolytic-uremic syndrome who had major neurological symptoms during the acute illness were neurologically and cognitively evaluated prospectively several years after recovery from the illness. Four patients showed evidence of subtle neurological sequelae, including posturing, clumsiness, poor fine-motor coordination, hyperactivity, and distractibility. Psychoeducational evaluation of all seven subjects revealed mean scores within the average range in cognitive abilities, academic achievement, single word receptive vocabulary, visual/motor planning, overall adaptive functioning, and hyperactivity. The lapse of time (minimum of 7 years) between the acute illness and the psychometric evaluation could have been responsible for our normal results.

  11. Volatile substance abuse: a review of possible long-term neurological, intellectual and psychiatric sequelae.

    Science.gov (United States)

    Ron, M A

    1986-03-01

    The possibility that chronic abuse of volatile substances can cause permanent neurological, psychiatric, and intellectual sequelae is critically reviewed. Toluene, present in the commonly used adhesives, is most often implicated in 'glue sniffing'; this review focuses on its potential long-term effects. Many criticisms--particularly poor matching of control samples and inability to distinguish between acute and chronic effects--can be levelled at the available studies, while no adequate follow-up studies have been performed. In the light of present knowledge, the possibility that permanent structural brain damage, with accompanying psychiatric manifestations, results from solvent abuse remains inconclusive.

  12. Eustachian tube dysfunction and its sequelae in patients with cleft palate.

    Science.gov (United States)

    Goldman, J L; Martinez, S A; Ganzel, T M

    1993-11-01

    The incidence of middle ear disorders in patients with cleft palate deformities was determined in a retrospective review of 110 children with palate or palate and lip involvement. Ages ranged from 2 months to 18 years and included patients with associated abnormalities such as Pierre Robin syndrome and Treacher Collins syndrome. Clinical manifestations of eustachian tube dysfunction were found in 79% in the form of effusions, retraction pockets, adhesions, and ossicular erosion. Only two patients had confirmed cholesteatoma formation. Despite the low incidence of acquired cholesteatoma in these patients, the frequent occurrence of other disorders that affect hearing warrants early and aggressive otologic management to prevent long-term sequelae.

  13. Does the Influenza Vaccine Prevent Sequelae Such as Myocarditis from Developing?

    Science.gov (United States)

    Whitney, Ryan; Dazley, Jason; Gilbert, Ryan; Slim, Jihad

    2015-01-01

    Vaccination continues to be a valuable and simple procedure to guard patients from an illness that may prevent them from completing their normal everyday tasks, missing days of work, and even lead to unnecessary sequelae. The following case describes one of the many complications that are seen on a regular basis in any community hospital in different regions of the world. The objective of this publication is to remind the public and practitioner of the urgency to vaccinate each season; thereby, curbing the virus's ability to mutate and preventing unwanted consequences such as bacterial super infection or myocarditis. PMID:26392720

  14. Does the influenza vaccine prevent sequelae such as myocarditis from developing?

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    Ryan Whitney

    2015-01-01

    Full Text Available Vaccination continues to be a valuable and simple procedure to guard patients from an illness that may prevent them from completing their normal everyday tasks, missing days of work, and even lead to unnecessary sequelae. The following case describes one of the many complications that are seen on a regular basis in any community hospital in different regions of the world. The objective of this publication is to remind the public and practitioner of the urgency to vaccinate each season; thereby, curbing the virus′s ability to mutate and preventing unwanted consequences such as bacterial super infection or myocarditis.

  15. Abortion care for adolescent and young women.

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    Renner, Regina-Maria; de Guzman, Anna; Brahmi, Dalia

    2014-07-01

    Unintended pregnancy among adolescents (10-19years) and young women (20-24years) is a global public health problem. Adolescents face challenges in accessing safe abortion care. To determine, via a systematic data review, whether abortion care for adolescent and young women differs clinically from that for older women. In a comprehensive data review, the Cochrane Central Register of Controlled Trials, MEDLINE, and POPLINE databases were searched from the earliest data entered until November 2012. Randomized controlled trials and observational studies comparing effectiveness, safety, acceptability, and long-term sequelae of abortion care between adolescent/young women and older women were identified. Two reviewers independently extracted data, and the Cochrane guidelines and Newcastle-Ottawa Scale were used for quality assessment. In total, there were 25 studies including 346 000 women undergoing first- and second-trimester medical abortion, vacuum aspiration, or dilation and evacuation. Effectiveness and overall complications were similar among age groups. However, younger women had an increased risk for cervical laceration and a decreased risk of uterine perforation and mortality. Satisfaction and long-term depression were similar between age groups. Except for less uptake of intrauterine devices among adolescents, age did not affect post-abortion contraception. Evidence from various healthcare systems indicates that abortion is safe and efficacious among adolescent and young women. Clinical services should promote access to safe abortion for adolescents. © 2013.

  16. Avaliação espirométrica de doentes com sequela de tuberculose submetidos à lobectomia Spirometry evaluation in patient with tuberculosis sequelae treated by lobectomy

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    Elias Amorim

    2013-04-01

    Full Text Available OBJETIVO: Avaliar a espirometria no pré e pós-operatório de doentes com sequela de tuberculose, submetidos à lobectomia. MÉTODOS: Foram selecionados 20 doentes, com idade entre 15 e 56 anos, de ambos os sexos, com história pregressa de tratamento de tuberculose, apresentando infecção de repetição ou hemoptises. Foram submetidos à lobectomia pulmonar. O tempo de tratamento da tuberculose foi seis meses e o aparecimento dos sintomas entre um e 32 anos. Foram avaliadas a capacidade vital (CV, a capacidade vital forçada (CVF, o volume expiratório forçado (VEF1, o VEF1/CVF, o fluxo expiratório forçado (FEF e o pico de fluxo expiratório (PFE após o primeiro, terceiro e sexto meses em relação ao pré-operatório. O nível de significância (á aplicado em todos os testes foi 5%, ou seja, considerou-se significativo quando pOBJECTIVE: To evaluate pre and post-operative spirometry in patients with tuberculosis sequelae undergoing lobectomy. METHODS: We selected 20 patients, aged between 15 and 56 years, of both genders, with a history of tuberculosis treatment, with repeated infections or hemoptysis and indication of pulmonary lobectomy. The tuberculosis treatment time was six months, and onset of symptoms, between one and 32. We evaluated and compared vital capacity (VC, forced vital capacity (FVC, forced expiratory volume (FEV1, the FEV1/FVC, forced expiratory flow (FEF and peak expiratory flow (PEF preoperatively and after the first, third and sixth postoperative months (POM. The significance level (á used in all tests was 5%, ie, it was considered significant when p <0.05. RESULTS: The averages found were: Vital Capacity (VC - Preoperative: 2.83; 1st POM: 2.12; 3rd POM: 2.31; 6th POM: 2.43. Forced Vital Capacity (FVC - Preoperative: 2.97; 1st POM: 2.21; 3rd POM: 2.35; 6th POM: 2.53. Expiratory Volume in 1 second (FEV1 - Preoperative: 2.23; 1st POM: 1.75; 3rd POM: 1.81; 6th POM 1.97. There was marked decrease in lung function in

  17. Late Maternal Deaths and Deaths from Sequelae of Obstetric Causes in the Americas from 1999 to 2013: A Trend Analysis

    Science.gov (United States)

    de Cosio, Federico G.; Sanhueza, Antonio; Soliz, Patricia N.; Becerra-Posada, Francisco; Espinal, Marcos A.

    2016-01-01

    Background Data on maternal deaths occurring after the 42 days postpartum reference time is scarce; the objective of this analysis is to explore the trend and magnitude of late maternal deaths and deaths from sequelae of obstetric causes in the Americas between 1999 and 2013, and to recommend including these deaths in the monitoring of the Sustainable Development Goals (SDGs). Methods Exploratory data analysis enabled analyzing the magnitude and trend of late maternal deaths and deaths from sequelae of obstetric causes for seven countries of the Americas: Argentina, Brazil, Canada, Colombia, Cuba, Mexico and the United States. A Poisson regression model was developed to compare trends of late maternal deaths and deaths from sequelae of obstetric causes between two periods of time: 1999 to 2005 and 2006 to 2013; and to estimate the relative increase of these deaths in the two periods of time. Findings The proportion of late maternal deaths and deaths from sequelae of obstetric causes ranged between 2.40% (CI 0.85% – 5.48%) and 18.68% (CI 17.06% – 20.47%) in the seven countries. The ratio of late maternal deaths and deaths from sequelae of obstetric causes per 100,000 live births has increased by two times in the region of the Americas in the period 2006-2013 compared to the period 1999-2005. The regional relative increase of late maternal death was 2.46 (p<0.0001) times higher in the second period compared to the first. Interpretation Ascertainment of late maternal deaths and deaths from sequelae of obstetric causes has improved in the Americas since the early 2000’s due to improvements in the quality of information and the obstetric transition. Late and obstetric sequelae maternal deaths should be included in the monitoring of the SDGs as well as in the revision of the International Classification of Diseases’ 11th version (ICD-11). PMID:27626277

  18. Lack of pupil reflex and loss of consciousness predict 30-day neurological sequelae in patients with carbon monoxide poisoning.

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    Jian-Fang Zou

    Full Text Available Predicting the neurological sequelae of carbon monoxide poisoning (COP has not been well studied. We investigated the independent predictors of neurological sequelae in patients with COP and combined these predictors to predict the prognosis.This study was conducted at four hospitals in Shandong Province, China. Data were retrospectively collected from 258 patients with COP between November 1990 and October 2011. Thirty-day neurological sequelae were the primary endpoints.A lack of pupil reflex and a loss of consciousness appear to be independent predictors for neurological sequelae in patients with COP. The presence of either one had a sensitivity of 77.0% (95% confidence interval [CI]: 69.3-83.2, a specificity of 47.1% (95% CI: 38.3-56.0, positive predictive value (PPV of 62.9% (95% CI: 55.2-70.1, and a negative predictive value (NPV of 63.6% (95% CI: 52.6-73.4. With both predictors present, the sensitivity was 11.5% (95% CI: 6.9 to 18.3, the specificity was 99.2 (95% CI: 94.7-100.0, the PPV was 94.1% (95% CI: 69.2-99.7, and the NPV was 49.0% (95% CI: 42.5-55.5.The risk for neurological sequelae apparently increased with the number of independent predictors. In patients with both predictors, the risk for neurological sequelae was 94.1%. Almost all (99.2% patients with neither predictor had no neurological sequelae. This finding may help physicians make decisions about and dispositions for patients with COP. For patients with a higher risk, earlier treatment and more appropriate utilization of health care services, including hyperbaric oxygen, should be considered.

  19. Avaliação, por graduandos de enfermagem, de ambiente virtual de aprendizagem para ensino de fisiologia endócrina Evaluación, por graduandos de enfermería, del ambiente virtual de aprendizaje para la enseñanza de la fisiología endocrina Evaluation by nursing students in virtual learning environments for teaching endocrine physiology

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    Elaine Maria Leite Rangel

    2011-01-01

    Full Text Available OBJETIVO: Descrever a avaliação do Ambiente Virtual de Aprendizagem do TelEduc no ensino de Fisiologia Endócrina por graduandos de enfermagem de um Curso de Licenciatura em Enfermagem de uma universidade pública do interior do Estado de São Paulo. MÉTODOS: Estudo descritivo, transversal com análise quantitativa de dados e com amostra de 44 alunos. Para a coleta de dados, utilizou-se um instrumento que contemplava aspectos pedagógicos do ambiente virtual de aprendizagem: conteúdo, interação e atividades e aspectos técnicos: tempo de resposta e qualidade da interface. RESULTADOS: Na avaliação dos alunos, os dados apontaram que, na maioria das respostas obtidas, foi explicitado o atendimento dos itens compreendidos nas seguintes características: conteúdo (84,0%, interação (83,2%, atividades (89,3%, tempo de resposta (94,0% e qualidade da interface (95,8%. CONCLUSÃO: O ambiente virtual de aprendizagem do TelEduc mostrou-se uma ferramenta eficaz para apoiar o ensino de Fisiologia Endócrina.OBJETIVO: Describir la evaluación del Ambiente Virtual de Aprendizaje del TelEduc en la enseñanza de la Fisiología Endocrina por graduandos de enfermería de un Curso de Licenciatura en Enfermería de una universidad pública del interior del Estado de Sao Paulo. MÉTODOS: Estudio descriptivo, transversal con análisis cuantitativa de datos, realizado con una muestra de 44 alumnos. Para la recolección de los datos, se utilizó un instrumento que contemplaba aspectos pedagógicos del ambiente virtual de aprendizaje: contenido, interacción y actividades y aspectos técnicos: tiempo de respuesta y calidad de la interfase. RESULTADOS: En la evaluación de los alumnos, los datos apuntaron que, en la mayoría de las respuestas obtenidas, fue explicitada la atención de los items comprendidos en las siguientes características: contenido (84,0%, interacción (83,2%, actividades (89,3%, tiempo de respuesta (94,0% y calidad de la interfase (95

  20. Animal Models of Virus-Induced Neurobehavioral Sequelae: Recent Advances, Methodological Issues, and Future Prospects

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    Marco Bortolato

    2010-01-01

    Full Text Available Converging lines of clinical and epidemiological evidence suggest that viral infections in early developmental stages may be a causal factor in neuropsychiatric disorders such as schizophrenia, bipolar disorder, and autism-spectrum disorders. This etiological link, however, remains controversial in view of the lack of consistent and reproducible associations between viruses and mental illness. Animal models of virus-induced neurobehavioral disturbances afford powerful tools to test etiological hypotheses and explore pathophysiological mechanisms. Prenatal or neonatal inoculations of neurotropic agents (such as herpes-, influenza-, and retroviruses in rodents result in a broad spectrum of long-term alterations reminiscent of psychiatric abnormalities. Nevertheless, the complexity of these sequelae often poses methodological and interpretational challenges and thwarts their characterization. The recent conceptual advancements in psychiatric nosology and behavioral science may help determine new heuristic criteria to enhance the translational value of these models. A particularly critical issue is the identification of intermediate phenotypes, defined as quantifiable factors representing single neurochemical, neuropsychological, or neuroanatomical aspects of a diagnostic category. In this paper, we examine how the employment of these novel concepts may lead to new methodological refinements in the study of virus-induced neurobehavioral sequelae through animal models.

  1. Upper aerodigestive tract sequelae in severe enterovirus 71 infection: predictors and outcome.

    Science.gov (United States)

    Tsou, Yung-An; Cheng, Yuan-Kai; Chung, Hsiung-Kwan; Yeh, Yi-Chun; Lin, Chia-Der; Tsai, Ming-Hsui; Chang, Jeng-Sheng

    2008-01-01

    Enterovirus 71 (EV71) infection sequelae can be severe and life-threatening, and long-term follow-up outcomes remain unknown. Therefore, we conducted a retrospective follow-up study to review airway and neurological sequelae development in patients with severe EV71 infection. We also studied the incidence and risk factors for tracheotomy and gastrostomy requirement. We investigated 202 EV71-infected children according to their disease stage. Seventy-two of them were diagnosed to have EV71 encephalitis, which was characterized by myoclonus, ataxia, nystagmus, oculomotor palsy and bulbar palsy or combinations of these conditions. All the 72 patients required endotracheal intubation due to respiratory failure or ventilator dependence; among these, 14 underwent tracheostomy and 10 underwent gastrostomy. All patients were followed-up for at least 3 years after discharge. Predictors of tracheostomy and gastrostomy requirement were age predictors were age predictors of tracheostomy requirement and pulmonary edema as the significant risk factor for gastrostomy. Long-term neuropsychological impact was observed on children who present the signs of the pulmonary edema or hypotension in the early onset of the EV71 infection. EV71-infected patients who develop neurological pulmonary edema or hypotension should be hemodynamically stabilized and undergo early tracheostomy to prevent further complications. This may improve the decannulation success rate after the brainstem function recovers.

  2. Intraoperative Hemorrhage and Postoperative Sequelae after Intraoral Vertical Ramus Osteotomy to Treat Mandibular Prognathism

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    Chun-Ming Chen

    2015-01-01

    Full Text Available Objective. To investigate the factors affecting intraoperative hemorrhage and postoperative sequelae after orthognathic surgery. Materials and Methods. Eighty patients with mandibular prognathism underwent surgical mandibular setback with intraoral vertical ramus osteotomy (IVRO. The correlation between the blood loss volume and postoperative VAS with the gender, age, and operating time was assessed using the t-test and Spearman rank correlation coefficient. The correlation between the magnitude of mandibular setback with the presence of TMJ clicking symptoms and lip sensation was also assessed. Results. The mean operating time and blood loss volume for men and women were 249.52 min and 229.39 min, and 104.03 mL and 86.12 mL, respectively. The mean VAS in men and women was 3.21 and 2.93, and 1.79 and 1.32 on the first and second postoperative days. There is no gender difference in the operating time, blood loss, VAS, TMJ symptoms, and lip numbness. The magnitude of mandibular setback was not correlated with immediate and long-term postoperative lip numbness. Conclusion. There are no gender differences in the intraoperative hemorrhage and postoperative sequelae (pain, lip numbness, and TMJ symptoms. In addition, neither symptom was significantly correlated with the amount of mandibular setback.

  3. Effects of Standardized Rehabilitation on Quality of Life of Stroke Patients at Convalescence and Sequelae Stages

    Institute of Scientific and Technical Information of China (English)

    XU Dongyan; JIA Jie; WU Yi; LI Mingfen; XIE Hongyu; YU Kewei; GUO Zhenzhen

    2013-01-01

    Objective:To explore the effects of standardized rehabilitation on quality of life (QOL) of stroke patients at convalescence and sequelae stages.Method:A total of 251 stroke patients were randomly divided into a standardized rehabilitation group and a control group.The simplified Fugl-Meyer assessment(FMA) scale,the 36-item short-form health survey questionnaire (SF-36) and functional comprehensive assessment (FCA) were administered before as well as after 3,6and at 12 months a follow-up study respectively.Statistical analysis was conducted based on the evaluations at 4 testing time points.Result:There was no significant difference in FMA,SF-36 and FCA scores of the two groups before and after 3 months treatments,while FMA,SF-36 and FCA scores of the rehabilitation group were obviously higher than those of the control group either after 6 months treatments or of follow-up study.Moreover,after 6 months treatments FMA score was apparently higher than the score at the beginning and after 3 months treatments.The FMA,SF-36 and FAC scores during the follow-up visit decreased when compared with scores after 6 months treatments,but increased significantly when compared with the scores at the beginning and after 3months treatments.Conclusion:Standardized tertiary rehabilitation (STR) at convalescence and sequelae stages can significantly improve motor functions and QOL of stroke patients.

  4. Neuropsychological and neuroanatomical sequelae of chronic non-malignant pain and opioid analgesia.

    Science.gov (United States)

    Block, Cady; Cianfrini, Leanne

    2013-01-01

    The pervasive disease of chronic pain is a common challenge for the clinical rehabilitation professional. Concurrent with physical and emotional symptoms, pain-related cognitive impairment has been reported. Although opioid analgesics are frequently prescribed, concern exists that opioids possess adverse cognitive effects of their own. To review the neuropsychological and neuroanatomical sequelae of chronic non-malignant pain and opioid therapy, to clarify roles and benefits of neuropsychological assessment in a chronic pain population, and to provide recommendations for clinical practice and future research. This non-systematic review sought to provide a comprehensive synthesis of relevant neurobiology, neuroimaging, neuropsychological, and rehabilitation research literatures. We included citations from seminal and current texts as well as relevant original and review articles from 1980-2012 in PubMed and PubMedCentral online research databases. To date, evidence from opioid studies suggests only mild deficits in specific cognitive domains (e.g., memory, attention/concentration) and only under specific conditions (e.g., dose escalations). Additionally, neuroimaging and neuropsychological evidence suggests that pain itself results in cognitive sequelae. Methodological improvements in future research will allow for better delineation of the contributing effects of pain and opioids, with an overall goal of improving evidence-based clinical treatment recommendations.

  5. Postural Control of Healthy Elderly Individuals Compared to Elderly Individuals with Stroke Sequelae.

    Science.gov (United States)

    Alfieri, Fábio Marcon; Riberto, Marcelo; Lopes, José Augusto Fernandes; Filippo, Thais Raquel; Imamura, Marta; Battistella, Linamara Rizzo

    2016-01-01

    A stroke and aging process can modify the postural control. We aimed to compare the postural control of health elderly individuals to that of individuals with stroke sequelae. This cross-sectional transversal study was made with individuals capable of walking without any assistance and that were considered clinically stable. The study had 18 individuals in the group with stroke sequelae (SG) and 34 in the healthy elderly control group (CG). The participants were evaluated for the timed up and go test (TUG) and force platform. The SG showed the worst results in relation to the time of execution of the TUG and the force platform evaluation. The displacement of center of pressure was worse for both groups in the eyes-closed situation, especially in the anteroposterior direction for the CG. The GS showed worse results in the static and dynamic postural control. The healthy elderly showed more dependence on sight to maintain their static balance and there was no difference in the balance tests in relation to the side affected by the stroke.

  6. Neurological sequelae of hospitalized Japanese encephalitis cases in Gansu province, China.

    Science.gov (United States)

    Yin, Zundong; Wang, Xuxia; Li, Li; Li, Hui; Zhang, Xiaoshu; Li, Junhong; Ning, Guijun; Li, Fengqin; Liang, Xuefeng; Gao, Li; Liang, Xiaofeng; Li, Yixing

    2015-06-01

    We conducted a follow-up survey for 55 Japanese encephalitis (JE) cases 1-2 years after hospital discharge in Gansu province, China. Community-, education-, and gender-matched healthy individuals without history of neurologic disease were selected as the comparison group. All subjects received neurological examination, intelligence quotient (IQ) measurement, adaptive behavior measurement, and Wechsler memory scale (WMS) assessment. We found 43.6% JE cases had at least one nervous system sequelae compared with 3.6% healthy individuals. Among JE cases, 22.4% had subnormal IQ, 18.4% subnormal verbal IQ (VIQ), 20.4% subnormal performance IQ (PIQ), and 78.4% had subnormal memory quotient (MQ). Among healthy individuals, 2.0% had subnormal IQ, VIQ, or PIQ and 8.1% had subnormal MQ. Among adult JE cases, 47.8% and 39.1% had adaptive behavior impairments and intellectual disability, respectively, compared with 18.8% and 9.7% among young cases, respectively. The results showed both adult and young surviving JE cases had significant neurological sequelae and mental disability 1-2 years after discharged. © The American Society of Tropical Medicine and Hygiene.

  7. [Maxillary advancement osteotomy with sequelae cleft lip and palate: Dilemma between occlusion and aesthetic profile].

    Science.gov (United States)

    Vigneron, A; Morand, B; Lafontaine, V; Lesne, V; Lesne, C; Bettega, G

    2015-11-01

    Maxillary hypoplasia is a common sequela of cleft lip and palate. Its surgical treatment consists in a maxillary advancement by distraction or by conventional orthognathic surgery but morphological results are unpredictable. Our goal in this study was to see if the esthetical results (on the lip and the nose) of maxillary advancement were correlated to the preservation of lateral incisor space of the cleft side. This retrospective study included 38 patients operated between 2002 and 2013. Unilateral clefts were studied independently from bilateral clefts. Profile aesthetics was evaluated independently and subjectively by two surgeons and scored on an 8-point scale. The result was classified as "good" if the score was superior or equal to 6. The score was correlated to the following parameters: amount of maxillary advancement, upper incisor axis, preservation of the missing lateral incisor space. In the "good result" group, the space of the lateral incisor was less often preserved. The nasolabial angle was more open and the upper central incisor axis more vertical. These results were more pronounced in bilateral clefts, but also found in unilateral clefts. Under reservation of the subjective evaluation and of the small number of patients, it seemed that lateral incisor space closure improved the profile of patients treated by maxillary advancement for cleft lip and palate sequelae. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  8. Adolescents as victims and perpetrators of violence.

    Science.gov (United States)

    Legano, Lori; McHugh, Margaret

    2013-04-01

    The hallmark of adolescent development is risk-taking behavior, mostly benign in nature, with no sequelae in adulthood. For that small number of adolescents for whom risk-taking behaviors are dangerous, for themselves and others, there are common childhood factors that may lead to those behaviors. In studies of adolescent victims, as well as perpetrators, a common theme can be identified, ie, maltreatment. The adolescent who visits Internet chat rooms, meets unknown individuals, and is later sexually assaulted by that individual is often a victim of sexual abuse in earlier childhood. Studies demonstrate that when adolescents are perpetrators of violent acts, they have a history of childhood physical abuse and often ongoing exposure to violence in their homes. For victims and perpetrators, there can be a common source of primary prevention in children rather than secondary interventions later in adolescence. That source can be a medical care provider in a medical home. Discussion of Internet usage with a 10-year-old by a medical provider may prevent later victimization. Identification and provision of services to families involved in domestic violence situations can help children establish positive adult roles with peers and future partners.

  9. Navigating Adolescence with a Chronic Health Condition: A Perspective on the Psychological Effects of HAIR-AN Syndrome on Adolescent Girls

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    Kimberly K. McClanahan

    2006-01-01

    Full Text Available HAIR-AN syndrome is a subphenotype of polycystic ovary syndrome and is characterized by acne, obesity, hirsutism, and acanthosis nigricans. It usually manifests in early adolescence, a time of significant developmental change in females across physical, cognitive, social, and emotional domains. We contend that adolescent development for females is difficult, even in the best of circumstances, and having a chronic health condition, like HAIR-AN syndrome, will likely impact the afflicted individual’s development and psychological well-being. While many researchers have discussed the long-term health effects of HAIR-AN and similar disorders, little has been written about the potential psychological sequelae of HAIR-AN on the adolescent girl. We discuss the normal developmental sequence for adolescent girls across early, middle, and late adolescence; discuss common mental health problems that adolescents experience; define HAIR-AN syndrome and its clinical manifestations; and discuss its likely psychological impact on adolescent girls. We also make suggestions for future clinical interventions and research in the area of HAIR-AN syndrome and its psychological sequelae.

  10. The neurobehavioural rating scale: assessment of the behavioural sequelae of head injury by the clinician.

    Science.gov (United States)

    Levin, H S; High, W M; Goethe, K E; Sisson, R A; Overall, J E; Rhoades, H M; Eisenberg, H M; Kalisky, Z; Gary, H E

    1987-01-01

    To investigate the inter-rater reliability and validity of the Neurobehavioural Rating Scale at various stages of recovery after hospitalisation for closed head injury, we studied 101 head trauma patients who had no antecedent neuropsychiatric disorder. The results demonstrated satisfactory inter-rater reliability and showed that the Neurobehavioural Rating Scale reflects both the severity and chronicity of closed head injury. A principal components analysis revealed four factors which were differentially related to severity of head injury and the presence of a frontal lobe mass lesion. Although our findings provide support for utilising clinical ratings of behaviour to investigate sequelae of head injury, extension of this technique to other settings is necessary to evaluate the distinctiveness of the neurobehavioural profile of closed head injury as compared with other aetiologies of brain damage. PMID:3572433

  11. Spontaneous bronchoesophageal fistula in an adult – A possible delayed sequela of pulmonary tuberculosis

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    Surendra Patel

    2015-01-01

    Full Text Available Spontaneous bronchoesophageal fistula in the adult is a rare clinical entity. Most bronchoesophageal fistulae are due to malignancy, prolonged endotracheal intubation or trauma. Granulomatous infections like tuberculosis, HIV and mediastinitis are rare causes of acquired bronchoesophageal fistula. We report a case of a 50 year old man, treated for pulmonary tuberculosis 15 years ago, who developed a spontaneous bronchoesophageal fistula between the mid-esophagus and right main stem bronchus, having no history of malignancy or trauma. Surgical closure of the fistula was done and post operative recovery was uneventful. In this case, the bronchoesophageal fistula probably developed as a delayed sequela of pulmonary tuberculosis as the patient had no active signs of pulmonary tuberculosis clinically or histopathologically.

  12. Clinical-radiological evaluation of sequelae of stereotactic radiosurgery for intracranial arteriovenous malformations

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    Levy, R.P.; Fabrikant, J.I.; Frankel, K.A.; Phillips, M.H.; Steinberg, G.K.; Marks, M.P.; DeLaPaz, R.L.; Chuang, F.Y.S.

    1989-12-01

    Stereotactic heavy-charged-particle Bragg peak radiosurgery has been used to treat 322 patients with surgically-inaccessible intracranial vascular malformations. (The clinical results of this method for the treatment of angiographically demonstrable arteriovenous malformations (AVMs) and angiographically occult vascular malformations (AOVMs) of the brain are described in separate reports of this symposium). The great majority of patients have had an uneventful post-treatment course with satisfactory health outcomes. However, several categories of delayed sequelae of stereotactic radiosurgery have been identified, involving the vascular structures essential for the integrity of the brain tissue and the brain parenchyma directly. These categories reflect both reaction to injury and to alterations in regional hemodynamic status, and include vasogenic edema, occlusion of functional vasculature, radiation necrosis, and local or remote effects on cerebral arterial aneurysms. 10 refs., 7 figs., 1 tab.

  13. Physical methods of torture and their sequelae: a Sri Lankan perspective.

    Science.gov (United States)

    Perera, Priyanjith

    2007-04-01

    Methods of torture vary from country to country and sometimes within regions in the same country. Knowing torture methods used in a country or region assists in evaluating injuries, scars and other chronic sequelae of torture. Medical records of 100 victims of torture examined between 1998 and 2001 in the Judicial Medical Officer's Office in Colombo, Sri Lanka, were perused to gather data on torture methods used in Sri Lanka during that period. Altogether 68 methods of torture had been used on these victims. They included assault with blunt and sharp weapons, burns with lighted cigarettes, 'dry submarino', kicking, 'wet submarino', 'hanging', electric torture, 'falaka' and many more. However, only 18% of victims had any physical residual effects, highlighting the typical objective of torture, which is inflicting maximum pain without causing serious injury or death.

  14. NEUROLOGICAL SEQUELAE FOLLOWING ANAESTHETIC RECOVERY AFTER BILATERAL TOTAL KNEE REPLACEMENT – TWO CASE REPORTS

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    Harpreet

    2016-03-01

    Full Text Available BACKGROUND Thromboembolism is a common and serious complication of joint replacement surgery. Cognitive decline occurs in 5-29% of patients, undergoing major orthopaedic surgery. Many studies show that systemic embolism may occur in the absence of venous-arterial shunts leading to cognitive dysfunction and neurological sequelae. METHODS We present two cases of neurological consequences occurring post bilateral TKR. Cases were successfully done under Combined Spinal Epidural Anaesthesia. Steroids were not used intraoperatively. RESULTS Both cases had neurological complications following completion of surgery. First case had posterior circulation TIA while the other had a right upper motor neuron facial palsy. CONCLUSION We suspect both as cases of cerebral fat microembolism in the absence of any venous-arterial shunt.

  15. Neurocognitive sequelae of cerebral malaria in adults:A pilot study in Benguela Central Hospital, Angola

    Institute of Scientific and Technical Information of China (English)

    Bruno Peixoto; Isabel Kalei

    2013-01-01

    Objective: To characterize the neurocognitive sequelae of cerebral malaria (CM) in an adult sample of the city of Benguela, Angola. Methods:A neuropsychological assessment was carried out in 22 subjects with prior history of CM ranging from 6 to 12 months after the infection. The obtained results were compared to a control group with no previous history of cerebral malaria. The study was conducted in Benguela Central Hospital, Angola in 2011. Results: CM group obtained lower results on the two last trials of a verbal learning task and on an abstract reasoning test. Conclusions: CM is associated to a slower verbal learning rate and to difficulties in the ability to discriminate and perceive relations between new elements.

  16. ESTUDO DO MAPEAMENTO SENSORIAL DO ESQUELETO AXIAL E APENDICULAR DE PORTADORES DE SEQUELAS DE PARALISIA CEREBRAL

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    Marcelo de Oliveira Rosário

    2012-01-01

    Full Text Available A paralisia cerebral caracteriza-se por comprometimento de variável severidade do sistema nervoso central, de caráter não progressivo. Este estudo teve como objetivo, realizar o mapeamento sensorial (avaliação da sensibilidade por meio de dermátomos do esqueleto axial e apendicular de indivíduos portadores de sequelas de paralisia cerebral, para avaliar e verificar as principais alterações sensitivas dos mesmos e ainda, analisar a importância da avaliação somatossensorial ser realizada com esses indivíduos. Foi realizado o mapeamento sensorial com o uso dos monofilamentos de Semmes – Weinstein, em 22 indivíduos,com idade entre 5 e 32 anos, estudantes da E.E.E.V.M. Verificou-se uma maior média de alteração de sensibilidade sempre na região anterior dos membros e também, do esqueleto axial dos indivíduos avaliados. Na região posterior do esqueleto axial, encontraram-se alterações mais homogêneas do que na região anterior do mesmo, onde as alterações foram mais heterogêneas. Ainda,observou-se com o presente trabalho, por meio de análise quantitativa, que oesqueleto apendicular apresentou alterações mais significativamente relevantes quando comparadas com as alterações do esqueleto axial. Com base nos resultados obtidos, comprovou-se a importância de indivíduos com sequelas de paralisia cerebral receberem constantemente estímulos sensitivos, de forma global euniforme, e ainda, serem avaliados sensitivamente de forma adequada porfisioterapeutas.

  17. [Long-term sequelae of deep venous thrombosis of the legs. Experience with mesoglycan].

    Science.gov (United States)

    Prandoni, P; Cattelan, A M; Carta, M

    1989-01-01

    Ninety consecutive patients, affected by venographically proven deep-vein thrombosis (DVT) of the lower limbs, were given full-dose heparin followed by oral anticoagulants for 12 weeks, and then selected randomly to receive, for one year, either mesoglycan (72 mg/day orally) or placebo with a double-blind protocol. All patients wore elastic graduated compression stockings, and were prospectively followed for a period ranging from 5 to 48 months. In each scheduled examination programmed every three months for one year and then twice per year, an accurate clinical evaluation was performed and a predetermined objective score was applied. Furthermore, impedance plethysmography and Doppler ultrasound tests were executed serially to assess the persistence of venous obstruction and/or the development of valve incompetence. After a mean follow-up of 3 years, 80% of the patients were totally asymptomatic, and severe post-thrombotic sequelae (ulcer and/or edema associated with skin induration) were recorded in only 6 patients (6.6%). We failed to identify any correlation between post-thrombotic sequelae and persistence of venous obstruction (as shown by impedance plethysmography) or development of valve incompetence (as shown by Doppler ultrasound test). The behaviour of patients treated with mesoglycan did not differ from that of patients treated with placebo. However, objectively documented recurrences of DVT and/or pulmonary embolism were less frequent in patients treated with mesoglycan (6.6 vs 11.1%, non-significant difference), and the only two deaths attributable to pulmonary embolism occurred among the patients treated with placebo.(ABSTRACT TRUNCATED AT 250 WORDS)

  18. The costs of human Campylobacter infections and sequelae in the Netherlands: A DALY and cost-of-illness approach

    NARCIS (Netherlands)

    Mangen, M.J.J.; Havelaar, A.H.; Bernsen, R.A.J.A.M.; Koningsveld, van G.A.; Wit, de G.A.

    2007-01-01

    Campylobacter infections and sequelae pose an important public health problem for the Netherlands. With the help of a second order stochastic simulation model (using @Risk), confidence intervals (CI) for the associated disease burden (summing up morbidity and mortality) and the associated

  19. The Prospective Contribution of Childhood Maltreatment to Low Self-Worth, Low Relationship Quality, and Symptomatology across Adolescence: A Developmental-Organizational Perspective

    Science.gov (United States)

    Flynn, Megan; Cicchetti, Dante; Rogosch, Fred

    2014-01-01

    This research investigated the prospective contribution of childhood maltreatment to low self-worth, low relationship quality, and symptoms during adolescence. Further, the stability and cross-lagged effects of these sequelae of maltreatment were examined over time. History of maltreatment during childhood was obtained, and youth (407 maltreated,…

  20. The Prospective Contribution of Childhood Maltreatment to Low Self-Worth, Low Relationship Quality, and Symptomatology across Adolescence: A Developmental-Organizational Perspective

    Science.gov (United States)

    Flynn, Megan; Cicchetti, Dante; Rogosch, Fred

    2014-01-01

    This research investigated the prospective contribution of childhood maltreatment to low self-worth, low relationship quality, and symptoms during adolescence. Further, the stability and cross-lagged effects of these sequelae of maltreatment were examined over time. History of maltreatment during childhood was obtained, and youth (407 maltreated,…

  1. Therapy and prophylaxis of acute and late radiation-induced sequelae of the esophagus

    Energy Technology Data Exchange (ETDEWEB)

    Zimmermann, F.B.; Geinitz, H.; Feldmann, H.J. [Klinik und Poliklinik fuer Strahlentherapie und Radiologische Onkologie, Klinikum rechts der Isar, Muenchen (Germany)

    1998-11-01

    Background: Radiation-induced esophagitis is a frequent acute side effect in curative and palliative radiotherapy of thoracal and cervical tumors. Late reactions are rare but might be severe. Methods: A resarch for reports on prophylactic and supportive therapies of radiation-induced esophagitis was performed (Medline, Cancerlit, and others). Results: Nutrition must be ensured and symptomatic relief of sequelae is important, especially in the case of dysphagia. The latter can be improved by topic or systemic analgetics. If esophageal spasm occurs, calcium antagonists might help. In case of gastro-esophageal reflux proton pump inhibitors should be used. There is no effective prophylactic measure for radiation esophagitis. Late side effects with clinical relevance are rare in conventional radiotherapy. Chronic ulcera, fistula or stenosis may develop. Before any treatment, a tumor infiltration of the esophagus should be excluded by biopsy. This can lead more often to late complications than radiation therapy itself. Nutrition should be ensured by endoscopic dilation, stent-implantation, or endoscopic percutaneous gastrostomy. Local injection of steroids might be used to avoid an early restenosis. Conclusions: An intensive symptomatic therapy of acute esophagitis is reasonable. Effective prophylaxis do not exist. Late radiation induced sequelae is rare. Therefore, a tumor recurrenc e should be excluded in cases of dysphagia. Securing nutrition by PEG, stent, or port is well in the fore. (orig.) [Deutsch] Hintergrund: Die radiogene Oesophagitis ist eine haeufige akute Nebenwirkung bei kurativen wie palliativen Bestrahlungen thorakaler und zervikaler Tumoren. Spaete Gewebereaktionen sind selten, koennen aber schwerwiegend sein. Methode: Es wurde eine Literaturrecherche nach prophylaktischen und supportiven Therapien der radiogen verursachten Oesophagitis durchgefuehrt (Medline, Cancerlit und andere). Ergebnisse: Therapeutisch stehen die Sicherung der Ernaehrung und die

  2. Fixator-assisted tibial lengthening over a plate in a patient with sequelae of poliomyelitis.

    Science.gov (United States)

    Tosun, Haci Bayram; Serbest, Sancar; Uludag, Abuzer; Gumustas, Seyitali; Celik, Suat

    2016-11-01

    There are many techniques for limb lengthening. Lengthening over a plate is an alternative choice of fixation in children or when nailing is difficult. We present a new technique for tibial lengthening with using a monolateral external fixator over a lengthening plate.Lengthening over an intramedullary nail is a commonly used method in patients with short stature or limb-length discrepancy. However, in patients with a narrow and excessively sclerotic intramedullary cavity in the pediatric age group where the skeletal system has not yet fully developed, difficulties have been observed in lengthening methods with nailing.Therefore, in these cases, the use of lengthening techniques over a plate is an alternative treatment option. Nevertheless, in lengthening techniques over a plate, if one side of the osteotomy area cannot be fixed, associated mechanical axis problems have been reported.We applied tibia lengthening with external fixator assistance over a custom-made lengthening plate in a patient with sequelae of poliomyelitis. This new lengthening technique applied over a plate could be the solution to the problems observed in other lengthening techniques over a plate.

  3. The metaphyseal bone defect predicts outcome in reverse shoulder arthroplasty for proximal humerus fracture sequelae.

    Science.gov (United States)

    Greiner, Stefan; Uschok, Stephan; Herrmann, Sebastian; Gwinner, Clemens; Perka, Carsten; Scheibel, Markus

    2014-06-01

    Reverse shoulder arthroplasty (RSA) represents an established procedure for treatment of fracture sequelae (FS) after proximal humerus fractures. The present work evaluates which factors are of influence for the clinical outcome. Fifty cases (mean age 69, range 44-89) have been evaluated postoperatively clinically [Constant Score (CS)] and radiographically (mean FU 34; range 24-93 months). The type of primary treatment, the amount of a metaphyseal bone defect, the preoperative status of the rotator cuff, the number of previous operative interventions and the type of FS according to Boileau were analysed whether they are of influence for clinical outcome. The mean CS increased significantly from 16.9 ± 6.7 preoperatively to 54.1 ± 15.7 points postoperatively. The CS of primary conservative treatment was significantly higher in comparison to primary operative treatment. Patients with a metaphyseal bone defect of more than 3 cm had significantly lower CS results. Degenerative changes of the teres minor muscle also had a significant negative influence on clinical results. Score results decreased with increasing number of previous operations. There were no significant difference in between patients classified as Boileau type I and II (category 1) compared to types III and IV (category 2). RSA significantly improved the clinical result. A metaphyseal bone defect and preoperative degeneration of the teres minor showed to be negative prognostic factors. Primary operative treatment and the number of previous operations also negatively influenced the clinical result.

  4. Minimizing the effect of TBI-related physical sequelae on vocational return.

    Science.gov (United States)

    McNamee, Shane; Walker, William; Cifu, David X; Wehman, Paul H

    2009-01-01

    This article evaluated the common physical sequelae that affect return to work (RTW) after traumatic brain injury (TBI). We performed a Medline search and evaluation of current TBI rehabilitation texts. The information presented is a combination of published literature and clinical guidelines. The limitations faced by many patients with TBI can best be overcome through clever job search, job redesign, and community linkages with business and industry that are willing to partner in helping the patient with TBI regain employment. The physician plays a key role in communicating suggestions to the vocational specialist. The comorbidities described represent challenges to successful RTW. These problems are recurrent, long-term, and clearly affect job procurement, nature of job, level of required support, and likelihood of job retention. Conversely, these challenges should not be viewed as impenetrable obstacles. With appropriate supports such as compensatory strategies, job coaching, assistive technology, medical management, and job restructuring, successful RTW is viable option. Physicians must focus on employment outcomes in real jobs and not settle for volunteer work, sheltered work, or assessment and planning. Individuals should be placed in real work for real pay. Through close collaboration between the survivor of TBI, the physician, the vocational specialist, and community resources, successful employment for survivors of TBI is possible and must be prescribed a high value.

  5. Global attentional-executive sequelae following surgical lesions to globus pallidus interna.

    Science.gov (United States)

    Scott, Richard B; Harrison, John; Boulton, Charlotte; Wilson, Joanna; Gregory, Ralph; Parkin, Simon; Bain, Peter G; Joint, Carol; Stein, John; Aziz, Tipu Z

    2002-03-01

    It has been demonstrated that selective unilateral surgical ablation of posteroventral globus pallidus interna relieves the movement disorders associated with advanced Parkinson's disease, without necessarily incurring the executive cognitive sequelae that have been observed following gross pathological lesions to this brain region. This finding is consistent with established theory that underlying neuronal circuitry is functionally segregated into parallel cortico-striatal-pallidal-thalamo-cortical 'loops'. We have studied a series of 12 patients with advanced Parkinson's disease at baseline, and then following bilateral pallidotomy, with a battery of neuropsychological tests including the Cambridge Neuro psychological Test Automated Battery. We identified a selective and universal loss of individual patients' ability to shift attention to novel dimensions in a test of abstract rule-learning following surgery, which was not reliably associated with any other change in cognition, personality, mood or medication. This finding is rare in its specificity and has implications for theoretical models of the functional architecture and pathophysiology of the globus pallidus, and the clinical practice of pallidotomy.

  6. Late sequelae of retained foreign bodies after world war II missile injuries.

    Science.gov (United States)

    Surov, Alexey; Thermann, Florian; Behrmann, Curd; Spielmann, Rolf-Peter; Kornhuber, Malte

    2012-09-01

    A number of people injured during the second world war harbour foreign bodies such as grenade splinters or bullets in some part of the body. Most of these metal fragments remain clinically silent. Some of them, however, may cause delayed complications. The purpose of this study was to determine the characteristics of delayed complications associated with foreign bodies after world war II injuries. 159 patients with retained foreign bodies after world war II injuries were retrospectively identified radiologically in our data bases in the time interval from 1997 to 2009. Diverse delayed complications secondary to the metal objects were diagnosed in 3 cases (2%): one patient with grenade splinter migration into the choledochal duct, one case with pseudotumoural tissue reaction, and one patient with late osteomyelitis. The time from injury to clinical presentation varied from 56 to 61 years. PubMed and Medline were screened for additional cases with delayed sequelae after foreign body acquisition during the 2nd world war. A 30 year search period from 1980 up to date was selected. 15 cases were identified here. Our study demonstrates that health consequences of the 2nd world war extend into the present time, and therefore physicians should be aware of the presence of hidden foreign bodies and their different possible late reactions.

  7. Neuroimaging assessment of early and late neurobiological sequelae of traumatic brain injury: implications for CTE

    Directory of Open Access Journals (Sweden)

    Mark eSundman

    2015-09-01

    Full Text Available Traumatic brain injury (TBI has been increasingly accepted as a major external risk factor for neurodegenerative morbidity and mortality. Recent evidence indicates that the resultant chronic neurobiological sequelae following head trauma may, at least in part, contribute to a pathologically distinct disease known as Chronic Traumatic Encephalopathy (CTE. The clinical manifestation of CTE is variable, but the symptoms of this progressive disease include impaired memory and cognition, affective disorders (i.e., impulsivity, aggression, depression, suicidality, etc., and diminished motor control. Notably, mounting evidence suggests that the pathology contributing to CTE may be caused by repetitive exposure to subconcussive hits to the head, even in those with no history of a clinically evident head injury. Given the millions of athletes and military personnel with potential exposure to repetitive subconcussive insults and TBI, CTE represents an important public health issue. However, the incidence rates and pathological mechanisms are still largely unknown, primarily due to the fact that there is no in vivo diagnostic tool. The primary objective of this manuscript is to address this limitation and discuss potential neuroimaging modalities that may be capable of diagnosing CTE in vivo through the detection of tau and other known pathological features. Additionally, we will discuss the challenges of TBI research, outline the known pathology of CTE (with an emphasis on Tau, review current neuroimaging modalities to assess the potential routes for in vivo diagnosis, and discuss the future directions of CTE research.

  8. A positive Babinski reflex predicts delayed neuropsychiatric sequelae in Chinese patients with carbon monoxide poisoning.

    Science.gov (United States)

    Zou, Jian-Fang; Guo, Qiming; Shao, Hua; Li, Bin; Du, Yuxiu; Liu, Maofeng; Liu, Fengling; Dai, Lixin; Chung, Min-Hsien; Lin, Hung-Jung; Guo, How-Ran; Yang, Tzu-Meng; Huang, Chien-Cheng; Hsu, Chien-Chin

    2014-01-01

    As the human population increased in China, the carbon monoxide is a serious environmental toxin in public health. However, predicting the delayed neuropsychiatric sequelae (DNS) of carbon monoxide poisoning (COP) has not been well studied. We investigated the independent predictors of DNS in patients with COP. This study was conducted at four hospitals in China. Data were retrospectively collected from 258 patients with COP between November 1990 and October 2011. DNS was the primary endpoint. A positive Babinski reflex was the independent predictor for DNS: sensitivity = 53.8% (95% confidence interval [CI]: 26.1-79.6), specificity = 88.6% (95% CI: 83.7-92.1), positive predictive value (PPV) = 20.0% (95% CI: 9.1-37.5), and negative predictive value (NPV) = 97.3% (95% CI: 94.0-98.9). The area under the receiver operating characteristic curve = 0.712 (95% CI: 0.544-0.880). A positive Babinski reflex was very memorable, immediately available, and applicable in clinical practice. Even when the sensitivity and PPV of a positive Babinski reflex were unsatisfactory, it had a good specificity and NPV for excluding the risk of DNS. In patients without a positive Babinski reflex, the risk for DNS was only 2.7%. This finding may help physicians make decisions about dispositions for patients with COP.

  9. Tomographic Aspects of Advanced Active Pulmonary Tuberculosis and Evaluation of Sequelae following Treatment

    Directory of Open Access Journals (Sweden)

    Rafael Barcelos Capone

    2017-01-01

    Full Text Available Objectives. To evaluate tomographic changes in pulmonary tuberculosis (TB, degree of agreement among three radiologists regarding tomographic diagnoses, and sequelae following treatment. Methods. Cross-sectional and descriptive study of 74 TB patients confirmed by sputum culture and chest computed tomography before (CT1 and 6 months after (CT2 drug therapy. Results were performed by three radiologists blinded to clinical and laboratory results. Results. Main findings in CT1 included nodules indicating the presence of a tree-in-bud pattern in 93% of cases, ill-defined nodules in 84% of cases, consolidation in 77% of cases, architectural distortion in 71% of cases, cavitary lesions in 62% of cases, and ground glass opacities in 37% of cases. Airway involvement, characterized by increased thickness and dilatation of the bronchial walls, occurred in 93% of cases. Pleural involvement occurred in 54%. There was an agreement on active TB among the three radiologists in 85% of cases. The results in CT2 indicated the presence of architectural distortion in 91% of cases and cylindrical bronchiectasis in 86%. Conclusions. The study established a tomographic pattern for diagnosis of active TB characterized by the presence of airway nodules, consolidation, architectural distortion, and cavitary lesions, and an almost complete degree of agreement (Kappa was observed among the radiologists (0.85. CT after treatment assists in defining the cure.

  10. Dysarthria and dysphagia as long-term sequelae in a child treated for posterior fossa tumour.

    Science.gov (United States)

    Cornwell, Petrea L; Murdoch, Bruce E; Ward, Elizabeth C; Morgan, Angela

    2003-01-01

    The current case report provides a comprehensive description of the persistent dysarthria and dysphagia evident in a 7.5 year old child treated for recurrent posterior fossa tumour (PFT). AC was assessed on a comprehensive perceptual and instrumental test battery incorporating all components of the speech production system (respiration, phonation, resonance, articulation and prosody) 2 years and 4 months following completion of her treatment. The nature of her swallowing impairment was investigated through the use of videofluoroscopic evaluation of swallowing (VFS). A mild dysarthria with ataxic and LMN components was identified, although overall speech intelligibility was not affected. A moderate dysphagia was also identified with impairment in all three phases of the swallowing process; oral preparatory, oral and pharyngeal. Dysarthria and dysphagia as persistent sequelae in children treated for PFT have implications for the long-term management of these children. The need for appropriate treatment regimes, as well as pre-surgical counselling regarding dysarthria and dysphagia as possible outcomes following surgery are highlighted.

  11. Enterococcus faecalis colonisation and endocarditis in five intensive care patients as late sequelae of selective decontamination.

    Science.gov (United States)

    Sijpkens, Y W; Buurke, E J; Ulrich, C; van Asselt, G J

    1995-03-01

    To describe Enterococcus faecalis colonisation and endocarditis in 5 intensive care patients after treatment with selective decontamination (SDD). Intensive care unit (ICU) in a general hospital. The patients were admitted to the ICU because of adult respiratory distress syndrome, polytrauma (2 patients), abdominal aortic surgery and gastrointestinal surgery. Because these patients needed mechanical ventilation they received systemic cefotaxime and SDD (polymyxin E, amphotericin B and norfloxacin). Colonisation with E. faecalis was documented in all patients. Intravascular catheter-related infection with E. faecalis occurred in 4 patients. None of the patients received antibiotics active against, E. faecalis, because body temperature normalised after catheter removal. In the course of his ICU stay one patient died. Autopsy showed E. faecalis endocarditis. The other 4 patients recovered from their primary illness, but had to be readmitted after several months because of E. faecalis endocarditis. One of these patients died. One patient recovered of endocarditis, but one year later valve surgery was necessary. The other 2 patients needed acute valve replacement. The latter 3 patients survived. We observed 5 patients with E. faecalis endocarditis as a late and severe sequela of SDD during their ICU stay.

  12. Characteristics and sequelae of erupted supernumerary teeth: A study of 218 cases among Sri Lankan children.

    Science.gov (United States)

    Herath, Chandra; Jayawardena, Chantha; Nagarathne, Nandani; Perera, Kanthi

    2016-12-19

    In the present study, we investigated the characteristics and sequelae of erupted supernumerary teeth (ST) in a sample of Sri Lankan children. Data were recorded from patients' clinical records, radiographs, models, and extracted teeth. The sample consisted of 239 ST from 218 patients. The mean age of the sample was 9.08 ± 2.47 years. The male-to-female ratio was 2.8:1. The majority (42.66%) of patients with ST were in aged 8-10 years. Many (94.94%) of the ST were located in the premaxilla (incisor), followed by the canine (4.22%), premolar (0.42%), and molar (0.42%) regions. The most common shape of ST teeth was conical. Malocclusion (59.83%) was the major problem associated with ST, and the clinical impact was highest on the 8-10-year age group. A strong association was observed between patients' age and clinical impact to the dentition (χ(2) =42.09, P=.000). Because the majority of ST can lead to malocclusion, especially in mixed dentition, awareness, early detection, and timely clinical intervention of ST are recommended. © 2016 John Wiley & Sons Australia, Ltd.

  13. A Positive Babinski Reflex Predicts Delayed Neuropsychiatric Sequelae in Chinese Patients with Carbon Monoxide Poisoning

    Directory of Open Access Journals (Sweden)

    Jian-Fang Zou

    2014-01-01

    Full Text Available As the human population increased in China, the carbon monoxide is a serious environmental toxin in public health. However, predicting the delayed neuropsychiatric sequelae (DNS of carbon monoxide poisoning (COP has not been well studied. We investigated the independent predictors of DNS in patients with COP. This study was conducted at four hospitals in China. Data were retrospectively collected from 258 patients with COP between November 1990 and October 2011. DNS was the primary endpoint. A positive Babinski reflex was the independent predictor for DNS: sensitivity = 53.8% (95% confidence interval [CI]: 26.1–79.6, specificity = 88.6% (95% CI: 83.7–92.1, positive predictive value (PPV = 20.0% (95% CI: 9.1–37.5, and negative predictive value (NPV = 97.3% (95% CI: 94.0–98.9. The area under the receiver operating characteristic curve = 0.712 (95% CI: 0.544–0.880. A positive Babinski reflex was very memorable, immediately available, and applicable in clinical practice. Even when the sensitivity and PPV of a positive Babinski reflex were unsatisfactory, it had a good specificity and NPV for excluding the risk of DNS. In patients without a positive Babinski reflex, the risk for DNS was only 2.7%. This finding may help physicians make decisions about dispositions for patients with COP.

  14. Narrative Exposure Therapy: A Proposed Model to Address Intimate Partner Violence-Related PTSD in Parenting and Pregnant Adolescents.

    Science.gov (United States)

    Volpe, Ellen M; Quinn, Camille R; Resch, Kathryn; Sommers, Marilyn S; Wieling, Elizabeth; Cerulli, Catherine

    2015-09-29

    Pregnant and parenting adolescents experience high rates of intimate partner violence (IPV) and its sequelae posttraumatic stress disorder (PTSD) and depression. Narrative exposure therapy (NET) is an innovative intervention that has demonstrated strong preliminary evidence in improving mental health. The specific aims of this article are 3-fold: (1) provide a brief background about IPV-related PTSD and depression among pregnant and parenting adolescents; (2) describe NET's theoretical principles, its therapeutic process, and provide a review of existing evidence; and (3) discuss NET as a potential treatment to address the mental health burden among adolescents experiencing IPV-related PTSD and depression.

  15. Hepato-biliary late effects in survivors of childhood and adolescent cancer: a report from the Children's Oncology Group.

    Science.gov (United States)

    Castellino, Sharon; Muir, Andrew; Shah, Ami; Shope, Sheila; McMullen, Kevin; Ruble, Kathy; Barber, Ashley; Davidoff, Andrew; Hudson, Melissa M

    2010-05-01

    Curative therapy for childhood and adolescent cancer translates to 1 in 640 young adults being a survivor of cancer. Although acute hepato-biliary toxicity occurs commonly during pediatric cancer therapy, the impact of antineoplastic therapy on long-term liver health in childhood/adolescent cancer survivors is unknown. This article reviews the medical literature on late liver dysfunction following treatment for childhood/adolescent cancer. We also outline the Children's Oncology Group (COG) guidelines for screening and follow-up of hepato-biliary sequelae. As the population of survivors grow and age, vigilance for risks to hepatic health needs to continue based on specific exposures during curative cancer therapy.

  16. Late bone and soft tissue sequelae of childhood radiotherapy. Relevance of treatment age and radiation dose in 146 children treated between 1970 and 1997

    Energy Technology Data Exchange (ETDEWEB)

    Doerr, W. [Technical Univ. of Dresden (Germany). Dept. of Radiotherapy and Radiation Oncology; Medical University / AKH Vienna (Austria). Dept. of Radiation Oncology; Kallfels, S. [Technical Univ. of Dresden (Germany). Dept. of Radiotherapy and Radiation Oncology; Kinder- und Jugendmedizin, Chemnitz (Germany); Herrmann, T. [Technical Univ. of Dresden (Germany). Dept. of Radiotherapy and Radiation Oncology

    2013-07-15

    Purpose: The present retrospective study was initiated to characterize the effect of oncological treatments in children and adolescents on bone and soft tissues, and to assess their dependence on radiation dose and age at exposure. Patients and methods: The study included 146 patients treated between 1970 and 1997. All patients received external beam radiotherapy to the trunk or extremities, but no cranial irradiation. Median age at treatment was 8.8 years. Patients were screened at 18 years (median time interval since treatment 9.2 years, range 0.9-17.7 years) for pathological changes in the skeletal system and soft tissues (scoliosis, kyphosis, bony hypoplasia, soft tissue defects, asymmetries), which were classified as minor/moderate (grade 1) or substantial (grade 2). Results: Pathological findings were recorded in 75/146 patients (51 %). These were scored as minor in 44 (59 %) and substantial in 31 patients (41 %). Most pathological changes occurred in children treated under the age of 6 years. At 6 years and older, only doses > 35 Gy caused an effect, and no substantial changes were seen for treatment ages exceeding 12 years. Significant effects of radiation dose and age at exposure were observed for kyphoscoliosis (with vertebral body dose gradients < 35 Gy), hypoplasia and soft tissue defects and asymmetrical growth. Conclusion: Tolerance doses of 20 Gy need to be respected for growing bone, particularly in children treated under the age of 6 years. The late treatment sequelae analysed in the present study are largely avoided with the use of current therapeutic protocols. However, the systematic evaluation, documentation and continuous analysis of adverse events in paediatric oncology remains essential, as does the evaluation of novel radio(chemo)therapeutic approaches. (orig.)

  17. Adolescent development

    Science.gov (United States)

    ... such experiences may have a harder time with intimate relationships when they are adults. Adolescents very often have ... family, school or social organizations, peer groups, and intimate relationships. PARENTING TIPS ABOUT SEXUALITY Adolescents most often need ...

  18. The Improvement Two Cases Coughing and Sputum sign Sequela of Pneumonia by Homins Placenta Aqua-Acupuncture

    Directory of Open Access Journals (Sweden)

    Kim, Eun-Gon

    2003-12-01

    Full Text Available Coughing and sputum are symptoms of sequela of Pneumonia. Oriental medicine call it Hae su. Hae su is common sign of lung disease. Hominis Placenta is the dried placenta of a healthy women. The nature of Hominis Placenta is warm and its taste sweet-salty. It has correspondence to the meridians of lung and kindey. Hominis Placenta acupuncture therapy has effect on invigoration of vital energy nourishing blood and tonifying the essence. It can be applied to the disease as Asthma, pulmonary tuberculosis, chronic hepatitis, liver cirrhosis, degenerative change and cerebrovascular disease. We treated two cases coughing and sputum sign Sequela of Pneumonia by Hominis Placenta Aqua-Acupuncture. The symptoms was improved and the patients satisfied

  19. Poor neurological sequelae of herpes simplex virus encephalitis in an infant despite adequate antiviral and adjunct corticosteroid therapy

    Directory of Open Access Journals (Sweden)

    Ratna B Basak

    2011-01-01

    Full Text Available A 2-month-old infant presented to our emergency department with fever, altered consciousness, and focal seizures of acute onset. He had vesicular skin lesions over the right preauricular region. CT brain showed a large hypodense lesion involving the left temporo-parietal region, left basal ganglia and left thalamus. MRI brain revealed bilateral multifocal corticomedullary lesions suggestive of encephalitis. CSF-PCR was positive for herpes simplex virus (HSV type I. He was treated with standard dose intravenous acyclovir for 15 days along with a trial of pulse methylprednisolone, but was readmitted within a week with features of an early relapse. The infant survived but developed significant neurological sequelae. Although treatment of HSV is available, the neurological outcome is guarded even with adequate antiviral therapy. Adjunct corticosteroid therapy did not appear to attenuate the neurological sequelae.

  20. Surgical treatment of burns sequelae. our experience in the Department of Plastic and Reconstructive Surgery, Pristina, Kosovo.

    Science.gov (United States)

    Buja, Z; Arifi, H; Hoxha, E; Duqi, S

    2015-09-30

    Burn injuries are very frequent in Kosovo, leading to long-lasting physical, functional, aesthetic, psychological and social consequences directly proportional to the time of healing; the longer it takes for the burn wound to heal, the more serious are the sequelae. The objectives of the present study are to review the epidemiological, clinical and therapeutic aspects of burn patients presenting with post-burn sequelae and treated at the Department of Plastic and Reconstructive Surgery, Pristina, Kosovo, from January 2005 until December 2011. This study included 188 patients with burns sequelae. The following variables were considered: age, sex, anatomical location, pathological types, and surgical procedure. There were 82 men (43.6%) and 106 women (56.4%), ranging in age from 0 to 67 years (mean age 33.5 years), most of the patients were children (139 = 73.9%). Burn contractures were observed in 135 (71.8%) patients, hypertrophic scars in 32 (17%), keloids in 10 (5.3%), alopecia in 6 (3.2%), syndactyly in 12 (6.4%), ectropion in 4 (2.1%) and ear deformity in 1 (0.53%) cases. To correct the deformities the most common choice was the Z-plasty technique, used in 31.4% of cases, followed by Z-plasty+full thickness skin grafts in 21.8%, full thickness skin grafts in 18.1%, tissue expansion in 8%, Z-plasty+local flaps in 4.8%, flaps (local, fascio-cutaneous, radial forearm) in 6.9% and direct closure in 6.4%. Timely wound closure and the development of an individual programme for surgical treatment of burns sequelae are crucial for optimal outcomes in patients with burns.

  1. Hydrokinesitherapy program using the Halliwick method on strength endurance and flexibility in a person with poliomyelitis sequelae

    OpenAIRE

    Paulina Yesica Ochoa Martínez; Javier Arturo Hall López; Adriana Griselda Mateos Valenzuela

    2015-01-01

    This case study attempts to determine the effect of ahydrokinesitherapy program by means of the Halliwickmethod on physical fitness in a female aged 35 yearswith poliomyelitis sequelae. The intervention followedsixteen weeks of hydrokinesitherapy during 70 minutes,five times a week, where we carried out exercises fromthe Halliwick method. There was an assessment both be-fore and after the application. Strength endurance andflexibility were determined according to a senior fitnesstest protocol...

  2. [Reconstructive surgery of sequelae of compartment syndrome of the lower leg and/or foot. Presentation of a new classification].

    Science.gov (United States)

    Zwipp, H

    2008-10-01

    The sequelae of an undiagnosed insufficiently treated or unpreventable (by crush injury) compartment or postischemic syndrome, most often after lower leg fracture or popliteal artery injury, are caused by necrosis and contracture of the extrinsic foot muscles. Therefore claw toes, pes equinus or other forms, such as a severe pes equino varus related to the compartment involved will decide the kind of foot deformity. In cases of a combined compartment syndrome of the lower leg and foot, not only the extrinsic but also the intrinsic muscles especially the short flexors are involved, leading to extensive claw toeing of the hallux and the lesser toes as well. In the case of an isolated compartment syndrome of the foot one will see contracted hammer toes most often after open or third degree closed calcaneal fractures. A new classification of all the different deformities of the foot and ankle as sequelae of a compartment and/or postischemic syndrome, is introduced distinguishing 5 degrees of deformity. Between 1994 and 2006, a total of 66 patients with sequelae of a compartment and/or postischemic syndrome were treated at the Department of Trauma and Reconstructive Surgery of the University Hospital"Carl Gustav Carus" of the Technical University of Dresden. Patients with contract hammer toes after calcaneal fractures were seen most often (n=26). Another large group of 24 patients suffered from the sequelae of a compartment and/or postischemic syndrome of the extrinsic muscles of the superficial and deeper compartment of the flexor tendons, producing a severe pes equino varus. Less common (n=16) were the deformities caused by an isolated compartment syndrome, such as necrosis of the anterior tibialis, long extensor muscles, peroneal muscles or a combined compartment syndrome of the lower leg and foot.

  3. Maternal cigarette smoking during pregnancy and cognitive performance in adolescence.

    Science.gov (United States)

    Kafouri, S; Leonard, G; Perron, M; Richer, L; Séguin, J R; Veillette, S; Pausova, Z; Paus, T

    2009-02-01

    The incidence of cigarette smoking during pregnancy remains high. Maternal smoking during pregnancy is known to be associated with cognitive and behavioural sequelae in childhood and adolescence. We assessed the relationship between maternal cigarette smoking during pregnancy and cognitive abilities in adolescent offspring (n = 503, 12- to 18-years old) using an extensive 6-h battery of tests. Non-exposed adolescents (controls) were matched to exposed adolescents (cases) by maternal education and school attended. Cognitive abilities were evaluated using a neuropsychological battery consisting of 33 tasks measuring verbal abilities, visuo-spatial skills, verbal and visual memory, processing speed, resistance to interference and motor dexterity. We found no differences between cases and controls in any of the cognitive domains whether potential confounders were included in the model or not. In addition to maternal smoking during pregnancy, we also evaluated the effect of sex and age on the various cognitive abilities in this large adolescent sample and found that most of the abilities continue to improve during adolescence to the same extent in girls and boys, with several age-independent sex differences. We found no effect of maternal cigarette smoking during pregnancy on cognitive abilities of the adolescent offspring when matching cases and controls by maternal education, the most common confounder of maternal cigarette smoking during pregnancy.

  4. Patterns of Local and Systemic Cytokines in Bacterial Meningitis and its Relation with Severity and Long-Term Sequelae

    Science.gov (United States)

    Perdomo-Celis, Federico; Torres, Miguel A.; Ostos, Henry; Gutierrez-Achury, Javier; Molano, Víctor; Durán, Luis F.; González, Guillermo; Narváez, Carlos F.

    2015-01-01

    Bacterial meningitis (BM) is a pyogenic infection present in the subarachnoid space, potentially fatal and frequently associated with neurological sequelae. During BM, cytokines (CTs) are locally produced. We sought to determine the CTs’ clinical role as disease severity predictors in adults, which is not completely clear. Using a bead-based flow cytometric assay, levels of six CTs were determined in cerebrospinal fluid (CSF) and plasma from 18 adult BM patients and 19 uninfected controls. Long-term neurological sequelae were evaluated using the Glasgow Outcome Scale (GOS). All evaluated CTs were higher in CSF than in plasma, and the levels of CSF interleukin (IL)-6, IL-8, IL-10, IL-1β, and tumor necrosis factor-α and plasma IL-10 and IL-12p70 were significantly higher in patients with severe sepsis than with sepsis, suggesting an association with clinical severity. There was a strong negative correlation between CSF IL-6 and plasma IL-12p70 with GOS score, supporting the possible role of these CTs in the development of neurological long-term sequelae. These findings could be helpful to identify candidates to receive neuroprotective treatments and early physiotherapy schemes. PMID:26715831

  5. [Cleft lip, alveolar and palate sequelae. Proposal of new alveolar score by the Alveolar Cleft Score (ACS) classification].

    Science.gov (United States)

    Molé, C; Simon, E

    2015-06-01

    The management of cleft lip, alveolar and palate sequelae remains problematic today. To optimize it, we tried to establish a new clinical index for diagnostic and prognostic purposes. Seven tissue indicators, that we consider to be important in the management of alveolar sequelae, are listed by assigning them individual scores. The final score, obtained by adding together the individual scores, can take a low, high or maximum value. We propose a new classification (ACS: Alveolar Cleft Score) that guides the therapeutic team to a prognosis approach, in terms of the recommended surgical and prosthetic reconstruction, the type of medical care required, and the preventive and supportive therapy to establish. Current studies are often only based on a standard radiological evaluation of the alveolar bone height at the cleft site. However, the gingival, the osseous and the cellular areas bordering the alveolar cleft sequelae induce many clinical parameters, which should be reflected in the morphological diagnosis, to better direct the surgical indications and the future prosthetic requirements, and to best maintain successful long term aesthetic and functional results. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  6. The Clinical Study on 34 Admission Patients due to Sequela of Traffic Accident

    Directory of Open Access Journals (Sweden)

    No, Bu-Rae

    2006-06-01

    Full Text Available Objectives : The purpose of this study was to investigate the clinical progress of patients diagnosed as sequela of traffic accident. Methods : We studied 34 cases who were admitted in Semyung University Oriental Hospital from 1st, January, 2005 to the 31st, December, 2005. And we came to some conclusion about clinical tendencies as follows. Results and Conclusions : 1. Women had occupied more than men, and 14 persons in 20th were the most distribution of age. 2. In distribution of onset, less than 7 days was the most(58.8 %, followed by less then 28 days(20.6 %. 3. Most patients used western medical hospital(47.1 % and oriental medical hospital(44.1 % as primary hospital. 4. In chief complaint, cervical pain was most(32 cases, 94.1%, the others were low back pain(22 cases, 64.7 %, back pain(5 cases, 14.7 %, chest pain(5 cases, 14.7 %. 5. In treatment methods, acupuncture and physical therapy was most(33 cases, 97.1%, the others were Extract-med.(31 cases, 94.0%, electric-acupuncture(27 cases, 79.4%, Herb-med.(23 cases, 67.6%, Herb-acupuncture(l8 cases, 52.9% and Taping therapy(15 cases, 44.1%. 6. In hospital days, days was most(l5 cases, 44.1%, the other were 15-21days(l2 cases, 35.3%. over the 29 days(4 cases, 11.8% and 22-28 days(3 cases, 8.8%. 7. 34 patients were examined, and all cases were 'improved'. And statistically significance compared after-treatment with before-treatment group(p<0.005.

  7. Antecedents and sequelae of sudden parental death in offspring and surviving caregivers.

    Science.gov (United States)

    Melhem, Nadine M; Walker, Monica; Moritz, Grace; Brent, David A

    2008-05-01

    To examine the psychiatric antecedents that put parents at risk for early death, and the psychological sequelae of bereavement in offspring and caregivers. A population-based study. Bereaved families were recruited through the coroner's records and by advertisement. Control families were recruited by random-digit dialing and advertisement. Families with biological offspring from 7 to 25 years of age in which 1 parent died of suicide, accident, or sudden natural death were included (n = 140). Controls (n = 99) had 2 living parents and their biological offspring and had no death of a first-degree relative within the past 2 years. Lifetime psychiatric history for deceased parents (probands) and new-onset psychiatric disorders, self-reported symptoms, and functional status in offspring and surviving caregivers. Bipolar disorder, substance abuse, and personality disorders are more common in probands who died of suicide or accident than in control parents. Bereaved offspring and their caregivers were at increased risk for depression and posttraumatic stress disorder. Bereaved offspring had a 3-fold (95% confidence interval, 1.3-7.0) increased risk of depression, even after controlling for antecedent and concomitant risk factors. Offspring bereaved by suicide showed similar outcomes compared with those bereaved by other types of death. Bereavement conveys an increased risk of depression and posttraumatic stress disorder above and beyond other vulnerability factors. Better integration of medical and psychiatric care may prevent premature parental death, but once it occurs, physicians should be alert to the increased risk for depression and posttraumatic stress disorder in bereaved offspring and their caregivers.

  8. Prenatal treatment for serious neurological sequelae of congenital toxoplasmosis: an observational prospective cohort study.

    Directory of Open Access Journals (Sweden)

    Mario Cortina-Borja

    2010-10-01

    Full Text Available BACKGROUND: The effectiveness of prenatal treatment to prevent serious neurological sequelae (SNSD of congenital toxoplasmosis is not known. METHODS AND FINDINGS: Congenital toxoplasmosis was prospectively identified by universal prenatal or neonatal screening in 14 European centres and children were followed for a median of 4 years. We evaluated determinants of postnatal death or SNSD defined by one or more of functional neurological abnormalities, severe bilateral visual impairment, or pregnancy termination for confirmed congenital toxoplasmosis. Two-thirds of the cohort received prenatal treatment (189/293; 65%. 23/293 (8% fetuses developed SNSD of which nine were pregnancy terminations. Prenatal treatment reduced the risk of SNSD. The odds ratio for prenatal treatment, adjusted for gestational age at maternal seroconversion, was 0.24 (95% Bayesian credible intervals 0.07-0.71. This effect was robust to most sensitivity analyses. The number of infected fetuses needed to be treated to prevent one case of SNSD was three (95% Bayesian credible intervals 2-15 after maternal seroconversion at 10 weeks, and 18 (9-75 at 30 weeks of gestation. Pyrimethamine-sulphonamide treatment did not reduce SNSD compared with spiramycin alone (adjusted odds ratio 0.78, 0.21-2.95. The proportion of live-born infants with intracranial lesions detected postnatally who developed SNSD was 31.0% (17.0%-38.1%. CONCLUSION: The finding that prenatal treatment reduced the risk of SNSD in infected fetuses should be interpreted with caution because of the low number of SNSD cases and uncertainty about the timing of maternal seroconversion. As these are observational data, policy decisions about screening require further evidence from a randomized trial of prenatal screening and from cost-effectiveness analyses that take into account the incidence and prevalence of maternal infection. Please see later in the article for the Editors' Summary.

  9. EFFECT OF ACUPUNCTURE ON BLOOD OXYGEN FREE RADICAL AND NO LEVELS IN TREATMENT OF APOPLECTIC SEQUELAE

    Institute of Scientific and Technical Information of China (English)

    袁青; 马瑞玲; 靳瑞

    2003-01-01

    Objective: To observe the effect of acupuncture on blood oxygen free radical (OFR) and nitric oxide(NO) levels in the treatment of apoplectic sequelae. Methods: A total of 61 cases of apoplectic patients were subject-ed into this study and randomly divided into "JIN San Zhen" group (n=30) and control group (n=31). Blood lipid per-oxidase (LPO), superoxide dismutase (SOD), glutathione peroxidase(GSH-Px) and nitric oxide (NO) contents beforeand after acupuncture treatment were determined with radioimmunoassay. In both groups, acupuncture was given oncedaily, six times a week, with 4 weeks being a therapeutic course and with the interval between two weeks being aweek, 3 courses all together. In "JIN San Zhen" group, acupoints of "JIN San Zhen" were used predominately, whilein control group, scalp-point Motor Sensory Area (MS 8) was used as the main point. Results: Self-comparison showedthat after 3 courses of treatment, in both groups, LPO and NO levels decreased significantly ( P < 0.05 - 0.01 ), SODand GST-Px values increased considerably ( P< 0.05 - 0.01 ). Comparison between two groups indicated that the ef-fects of "JIN San Zhen" group are significantly superior to those of control group in raising blood SOD and GST-Px lev-els ( P< 0.05- 0.01 ) and in lowering blood NO content ( P< 0.01 ). Analysis on the correlation between the restora-tion of neural function and the changes of LPO, SOD and GST-Px levels suggested that the effect of acupuncture in im-proving neural function may be related to changes of the aforementioned indexes. Conclusion: Acupuncture therapy cansignificantly lower blood LPO and NO levels and evidently raise blood SOD and GST-Px levels in stroke patients.

  10. Childhood central nervous system leukemia: historical perspectives, current therapy, and acute neurological sequelae

    Energy Technology Data Exchange (ETDEWEB)

    Laningham, Fred H. [St. Jude Children' s Research Hospital, Division of Diagnostic Imaging, Department of Radiological Sciences, Memphis, TN (United States); University of Tennessee Health Sciences Center, Memphis, TN (United States); Kun, Larry E. [St. Jude Children' s Research Hospital, Division of Radiation Oncology, Department of Radiological Sciences, Memphis, TN (United States); University of Tennessee Health Sciences Center, Memphis, TN (United States); Reddick, Wilburn E.; Ogg, Robert J. [St. Jude Children' s Research Hospital, Division of Translational Imaging Research, Department of Radiological Sciences, Memphis, TN (United States); Morris, E.B. [St. Jude Children' s Research Hospital, Department of Oncology, Memphis, TN (United States); Pui, Ching-Hon [St. Jude Children' s Research Hospital, Department of Oncology, Memphis, TN (United States); University of Tennessee Health Sciences Center, Memphis, TN (United States)

    2007-11-15

    During the past three decades, improvements in the treatment of childhood leukemia have resulted in high cure rates, particularly for acute lymphoblastic leukemia (ALL). Unfortunately, successful therapy has come with a price, as significant morbidity can result from neurological affects which harm the brain and spinal cord. The expectation and hope is that chemotherapy, as a primary means of CNS therapy, will result in acceptable disease control with less CNS morbidity than has been observed with combinations of chemotherapy and radiotherapy over the past several decades. In this review we discuss the poignant, historical aspects of CNS leukemia therapy, outline current methods of systemic and CNS leukemia therapy, and present imaging findings we have encountered in childhood leukemia patients with a variety of acute neurological conditions. A major objective of our research is to understand the neuroimaging correlates of acute and chronic effects of cancer and therapy. Specific features related to CNS leukemia and associated short-term toxicities, both disease- and therapy-related, are emphasized in this review with the specific neuroimaging findings. Specific CNS findings are similarly important when treating acute myelogenous leukemia (AML), and details of leukemic involvement and toxicities are also presented in this entity. Despite contemporary treatment approaches which favor the use of chemotherapy (including intrathecal therapy) over radiotherapy in the treatment of CNS leukemia, children still occasionally experience morbid neurotoxicity. Standard neuroimaging is sufficient to identify a variety of neurotoxic sequelae in children, and often suggest specific etiologies. Specific neuroimaging findings frequently indicate a need to alter antileukemia therapy. It is important to appreciate that intrathecal and high doses of systemic chemotherapy are not innocuous and are associated with acute, specific, recognizable, and often serious neurological

  11. Vein transplantion using human umbilical cord blood stem cells in the treatment of stroke sequela

    Institute of Scientific and Technical Information of China (English)

    Yong Man; Jianbin Li; Bo Yang; Ji Ma

    2006-01-01

    BACKGROUND: Transplanted mononuclear cell(MNC)of umbilical blood can survive in central nervous system (CNS)of host through blood brain barrier,differentiate into nerver cells,migrate to damaged site and integrate morphological strucgh and function with nerve cells of host so as to improve deficiencies of sensatory function,motor function and cognitive function and influence on stroke sequela.OBJECTIVE: To observe the vein transplantation of human umbilical cord blood stem cells(HUCBSC) for improving neurological function,limb funtion and activity of daily living of patients with stroke and evaluate the reliability.DESIGN: Self-controlled study.SETTING: Department of Neurosurgery,the Second People's Hospital of Zhengzhou City;Red-crossed Blood Center of Henan Province;Department of Neurosurgery,the Fist Affiliated Hospital of Zhenzhou University.PARTICIPANTS:A total of 10 patients with stoke sequela were selected from Department of Cerebral Surgery,the Second People's Hospital of Zhengzhou City from April to December 2005.There were 9males and 1 female aged from 35to 75years with the mean age of 56 years.All of them were diagnosed with CT and MRI examination and coincidence with diagnostic criteria of stroke established by the Fourth National Academic Meeting for Cerebrovascular Disease.All patients provided informed consent. METHODS:80-140 mL umbilical blood of term birth of newborn was selected hermetically and maintained in sterile plastic bag.And then,the blood was centrifugated at the speed of 1500 r/min for 30 minutes at 22℃ in order to separate MNC,i.e.,HUCBSC.In addition,after final diagnosis during hospitalization,stroke patients were perfused with HUCBSC through superficial vein of back of the hand.Each patient was averagely penfused with 6 portions of HUCBSC(cellular numbers≥1×108/portion)and the interval between each portion was 1-7 days with the mean interval of 4 days.MAIN OUTCOME MEASURES: ①Neurological function of stroke patients was

  12. Estudio del protooncogen Ret en neoplasia endocrina multiple 2A y en carcinoma medular en tiroides familiar: Hallazgos clínico-patológicos en portadores asintomáticos Analysis of the RET protooncogene in multiple endocrine neoplasia 2A and in familial medullary thyroid carcinoma: Clinical-pathological findings in asymptomatic carriers

    Directory of Open Access Journals (Sweden)

    S. Belli

    2003-01-01

    Full Text Available El 25% de los carcinomas medulares de tiroides son hereditarios. Se presentan en forma de familiar (CMTF 5% o como neoplasia endocrina múltiple (MEN tipo 2A (17% o 2B (3%, y comparten la herencia, autosómica dominante, de una mutación germinal en el protooncogen RET en uno de 12 codones conocidos. Estudiamos 7 familias (5 CMTF y 2 MEN 2A con el objeto de detectar la mutación familiar e identificar a los portadores asintomáticos. Seis de las siete mutaciones (4 CMTF y 2 MEN 2A fueron en el codón más frecuente, el 634, y una familia con CMTF presentó una mutación germinal novel: una transición T>C en el codón 630, resultando el cambio C630A. De los 57 individuos estudiados, 25 (43.85 % fueron portadores de la mutación, 7 de éstos (28% eran portadores asintomáticos de los cuales 5 eran niños, con una edad X-=11±3.2 años y fueron tiroidectomizados. Presentaron hiperplasia de células C y focos de microcarcinoma en ambos lóbulos tiroideos aun cuando la calcitonina basal o estimulada con pentagastrina fueron normales. En conclusión, describimos una mutación germinal novel en el protooncogen RET: C630A y el hallazgo de enfermedad de la célula C en los portadores asintomáticos, que enfatiza la importancia de la tiroidectomía profiláctica tan pronto como se confirma el diagnóstico molecular.Twenty five percent of the medullary thyroid carcinoma (MTC is hereditary and 5% is familiar (FMTC, or considered as multiple endocrine neoplasia (MEN type 2A (17% or 2B (3%. These diseases are the result of the autosomic dominant inheritance of a mutation in the RET protooncogene, in one out of 12 different known codons. We analyzed 7 families (2 MEN 2A and 5 FMTC. Six mutations were detected in the most frequent codon, 634 (2 MEN 2A y 4 FMTC and one family with FMTC presented a novel mutation: a transition T>C at codon 630, resulting a C630A change. Among 57 individuals studied, 25 (43.85% presented the mutation. Seven (28% were asymptomatic

  13. [Long term evaluation of sensation sequelae of bipedicled digital advancement island flaps. Comparison of clinical and electrophysiological results. Apropos of 13 cases].

    Science.gov (United States)

    Milliez, P Y; Parain, D; Menard, J F; Magnier, P; Plot, E

    1994-06-01

    Thirteen homodigital bipedicle island flaps for digital pulp amputation were reviewed to allow a better evaluation of sensory sequelae. A clinical and electrophysiological study of the sensory score of the pulp were compared to the contralateral normal digit and expressed in relative values. Sensory sequelae, even minor, are constant. The summated scores of dynamic and static 2 point discrimination test, appeared correlated to the electrophysiological amplitude modulations. This result seems particularly interesting as it adds another test for the objective evaluation of sensitivity.

  14. Long-term osseous sequelae after acute trauma of the knee joint evaluated by MRI

    Energy Technology Data Exchange (ETDEWEB)

    Roemer, F.W.; Bohndorf, K. [Department of Radiology, Klinikum Augsburg, Stenglinstrasse 2, 86152 Augsburg (Germany)

    2002-11-01

    articular surface injuries such as subchondral bone impaction or chondral/osteochondral fractures will heal without obvious osseous long-term sequelae. Post-traumatic osteonecrosis, as reported in the literature, must be a rare event after acute knee trauma. (orig.)

  15. [Adolescent pregnancy].

    Science.gov (United States)

    Lachcar, P

    1990-01-01

    The number of adolescent pregnancies brought to term in France has continued to decline while the number of abortions remains stable. Adolescent pregnancies cannot be considered "accidents" either in their social or psychological aspects. Pregnant adolescents carrying to term tend to be more disadvantaged than those seeking abortions. Early pregnancy may be a response to difficult life conditions. Despite appearing to constitute an infraction of a social code, adolescent pregnancy may in fact represent an attempt at social integration through motherhood. Adolescents failing in school, with poor employment prospects and feeling family pressures may view pregnancy as a means of social recognition. But such factors by themselves do not explain pregnancy; the primordial role of psychological factors must be examined. For some adolescents, pregnancy may represent an attempt to understand their own sexual identity as the transformations of puberty unsettle their previous self-images. Or they may be failing to perceive or actively denying the possibility of pregnancy. Adolescent pregnancies may be the result of transgressions of prohibitions. The traditional prohibition of sexual activity has relaxed to the degree that it is being replaced by a new prohibition on adolescent pregnancy and a prescription to use contraception. But contraception deprives an adolescent in search of sexual identity of proof of fertility as well as of the image of spontaneity and naturalness. Use of contraception is in conflict with the questions, doubts, and anxieties of adolescence. For adolescents in a reactivated oedipal stage, heterosexuality is often at the service of incestuous fantasies involving the mother. Abortion and perhaps pregnancy itself may assume the character of a rite of passage into adulthood for some adolescents. The important thing for many is the ability to become pregnant, to be a mother like their own mother.

  16. A one-year observational study of all hospitalized acute poisonings in Oslo: complications, treatment and sequelae

    Directory of Open Access Journals (Sweden)

    Lund Cathrine

    2012-07-01

    Full Text Available Abstract Objectives Changes in poisoning trends may affect both complications and outcomes in patients with acute poisoning. This study reports the treatments given and the frequency of complications, also related to treatment, mortality and sequelae related to various toxic agents. Methods All acute poisonings in adults (≥16 years admitted to the five hospitals in Oslo were included consecutively during one year (2008 to 2009 in an observational cross-sectional multicenter study. A standardized form was completed by the treating physician, which covered the study aims. Results There were 1065 admissions in 912 patients. The median length of hospital stay was one day, and 49% were observed in an intensive care unit (ICU. Active treatment was given to 83%, and consisted of supportive therapy (70%, antidote(s (38%, activated charcoal (16% and gastric lavage (9%. The most commonly used antidotes were flumazenil (19%, naloxone (17% and N-acetylcysteine (11%. The rate of treatment-related complications was 2.4% (21/884. Neither flumazenil, naloxone, nor the combination, was associated with convulsions or other complications. Among those receiving N-acetylcysteine, 5% (6/120 developed allergic reactions, one of which mandated discontinuation of treatment. Nineteen percent presented in a coma. Complications developed in 30%, compared with 18% in a 2003 study, mainly respiratory depression (12%, prolonged QTc interval (6% and hypotension (5%. Eight patients died (0.8% and five (0.5% survived with permanent sequelae, mainly anoxic brain damage. Discussion Few patients stayed more than two days. The use of the ICU was liberal, considering that only one out of five presented in a coma. Antidotes were frequently given diagnostically. Although N-acetylcysteine induced allergic reactions, most were mild and treatment discontinuation was only necessary once. The frequency of complications had almost doubled in five years, although the poisoning pattern was

  17. Tumor necrosis factor alpha production from CD8+ T cells mediates oviduct pathological sequelae following primary genital Chlamydia muridarum infection.

    Science.gov (United States)

    Murthy, Ashlesh K; Li, Weidang; Chaganty, Bharat K R; Kamalakaran, Sangamithra; Guentzel, M Neal; Seshu, J; Forsthuber, Thomas G; Zhong, Guangming; Arulanandam, Bernard P

    2011-07-01

    The immunopathogenesis of Chlamydia trachomatis-induced oviduct pathological sequelae is not well understood. Mice genetically deficient in perforin (perforin(-/-) mice) or tumor necrosis factor alpha (TNF-α) production (TNF-α(-/-) mice) displayed comparable vaginal chlamydial clearance rates but significantly reduced oviduct pathology (hydrosalpinx) compared to that of wild-type mice. Since both perforin and TNF-α are effector mechanisms of CD8(+) T cells, we evaluated the role of CD8(+) T cells during genital Chlamydia muridarum infection and oviduct sequelae. Following vaginal chlamydial challenge, (i) mice deficient in TAP I (and therefore the major histocompatibility complex [MHC] I pathway and CD8(+) T cells), (ii) wild-type mice depleted of CD8(+) T cells, and (iii) mice genetically deficient in CD8 (CD8(-/-) mice) all displayed similar levels of vaginal chlamydial clearance but significantly reduced hydrosalpinx, compared to those of wild-type C57BL/6 mice, suggesting a role for CD8(+) T cells in chlamydial pathogenesis. Repletion of CD8(-/-) mice with wild-type or perforin(-/-), but not TNF-α(-/-), CD8(+) T cells at the time of challenge restored hydrosalpinx to levels observed in wild-type C57BL/6 mice, suggesting that TNF-α production from CD8(+) T cells is important for pathogenesis. Additionally, repletion of TNF-α(-/-) mice with TNF-α(+/+) CD8(+) T cells significantly enhanced the incidence of hydrosalpinx and oviduct dilatation compared to those of TNF-α(-/-) mice but not to the levels found in wild-type mice, suggesting that TNF-α production from CD8(+) T cells and non-CD8(+) cells cooperates to induce optimal oviduct pathology following genital chlamydial infection. These results provide compelling new evidence supporting the contribution of CD8(+) T cells and TNF-α production to Chlamydia-induced reproductive tract sequelae.

  18. Premature loss of primary anterior teeth due to trauma--potential short- and long-term sequelae.

    Science.gov (United States)

    Holan, Gideon; Needleman, Howard L

    2014-04-01

    Traumatic dental injuries (TDIs) can result in the premature loss of primary anterior teeth due to an immediate avulsion, extraction later after the injury because of poor prognosis or late complications, or early exfoliation. There are a number of potential considerations or sequelae as a result of this premature loss that have been cited in the dental literature, which include esthetics, quality of life, eating, speech development, arch integrity (space loss), development and eruption of the permanent successors, and development of oral habits. This article provides a comprehensive review of the dental literature on the possible consequences of premature loss of maxillary primary incisors following TDI.

  19. Neurobehavioural sequelae of social deprivation in rodents revisited: Modelling social adversity for developmental neuropsychiatric disorders.

    Science.gov (United States)

    Robbins, T W

    2016-11-01

    The significance of investigating effects of deprivation of social experience in rodents is reviewed in the context of the review by Robbins et al. (1996) in the Journal of Psychopharmacology (10: 39-47). The early development of the paradigm by which rats were reared post-weaning in social isolation is described and compared with other early experience manipulations. The specification of the neural and behavioural phenotype of the isolate is brought up-to-date, focusing on changes in motivation and cognitive function, as well as on contrasting changes in the dopamine and serotonin systems, and in cortical (including hippocampal) structure and function. The relevance of the isolate for animal models of psychiatric disorders such as attention deficit hyperactivity disorder and schizophrenia is reviewed, and it is considered that the paradigm best exemplifies a manipulation that can be applied to test effects of certain forms of social adversity during adolescence on brain development and behaviour. © The Author(s) 2016.

  20. Long term sequelae of pediatric craniopharyngioma - literature review and 20 years of experience.

    Science.gov (United States)

    Cohen, Michal; Guger, Sharon; Hamilton, Jill

    2011-01-01

    Craniopharyngioma are rare histologically benign brain tumors that develop in the pituitary-hypothalamic area. They may invade nearby anatomical structures causing significant rates of neurological, neurocognitive, and endocrinological complications including remarkable hypothalamic damage. Information regarding long term implications of the tumors and treatment in the pediatric population is accumulating, and treatment goals appear to be changing accordingly. In this review we aim to present data regarding long term complications of craniopharyngioma in children and adolescents and our experience from a large tertiary center. Hypothalamic dysfunction was noted to be the most significant complication, adversely affecting quality of life in survivors. Obesity, fatigue, and sleep disorders are the most notable manifestations of this dysfunction, and treatment is extremely difficult. Changes in management in recent years show a potential for improved long term outcomes; we found a trend toward less aggressive surgical management and increasing use of adjuvant treatment, accompanied by a decrease in complication rates.

  1. Long term sequelae of pediatric craniopharyngioma - literature review and 20 years of experience

    Directory of Open Access Journals (Sweden)

    Michal eCohen

    2011-11-01

    Full Text Available Craniopharyngioma are rare histologically benign brain tumors that develop in the pituitary- hypothalamic area. They may invade nearby anatomical structures causing significant rates of neurological, neurocognitive and endocrinological complications including remarkable hypothalamic damage. Information regarding long term implications of the tumors and treatment in the pediatric population is accumulating, and treatment goals appear to be changing accordingly. In this review we aim to present data regarding long term complications of craniopharyngioma in children and adolescents and our experience from a large tertiary center. Hypothalamic dysfunction was noted to be the most significant complication, adversely affecting quality of life in survivors. Obesity, fatigue and sleep disorders are the most notable manifestations of this dysfunction, and treatment is extremely difficult. Changes in management in recent years show a potential for improved long term outcomes; we found a trend towards less aggressive surgical management and increasing use of adjuvant treatment, accompanied by a decrease in complication rates.

  2. Ankle fusion with a retrograde locked intramedullary nail for sequela of lower extremity compartment syndrome

    Institute of Scientific and Technical Information of China (English)

    WANG Xu; MA Xin; ZHANG Chao; HUANG Jia-zhang; GU Xiang-jie; JIANG Jian-yuan

    2012-01-01

    Objective: To assess the value of ankle fusion with a retrograde locked intramedullary nail in the treatment of sequela of lower extremity compartment syndrome.Methods:Thirty-five cases of equinus deformity following tibiofibular compartment syndrome treated by means of ankle fusion with a retrograde locked intramedullary nail from January 2001 to December 2010 were retrospectively reviewed.The complications,the time needed for bony fusion of the ankle joint assessed by anteroposterior and lateral X-ray photographs as well as patients' subjective evaluation were recorded and analysed.Results: Among the 35 patients,15 had previously undergone surgical treatment twice on the same limb,13 had thrice and 7 had to be operated on four times before ankle fusion.An anterior midpoint approach to the ankle joint was adopted in 29 cases,while anterior midpoint approach plus a small incision on the posterior ankle joint was made in 17 cases,whereas lateral approach in 6 cases.Tarsus joint fusion was performed on 4 cases.The follow-up period ranged 6-124 months,averaged 40.6 months.Bone grafting was not performed in this series.Preoperative tibial shaft fracture occurred in one patient and was healed after conservative treatment.Incision dehiscence located at previous Achilles tendon incision was found in two patients.As a result,one received an intramedullary nail emplacement at calcaneoplantar part while the wound at anterosuperior part of the other one was healed by dressing change.Two patients failed to bony union 5 months postoperatively,in which one healed 10 weeks after retrieval of proximal tibial nail and another by iliac grafting.Terminal necrosis of the toe due to blood supply dysfunction was not found in this series.All the patients were satisfied with the ankle joint function postoperatively.The time for bony union on X-rays was 9.8 weeks on average.Except for one patient who demanded removal of intramedullary nail,all the intramedullary nails were not retrieved at

  3. Positively Adolescent!

    Science.gov (United States)

    Williamson, Sue

    2000-01-01

    Believes that music teachers should reassess their views toward adolescent behavior in the music classroom by learning to see their behavior in a positive light. Describes teaching strategies that build on four adolescent behaviors: (1) desire for peer acceptance; (2) abundant energy; (3) love of fun; and (4) limited time-managing skills. (CMK)

  4. Adolescent Loneliness.

    Science.gov (United States)

    Goldenberg, Sheila

    Research has suggested that the incidence of loneliness peaks at adolescence and decreases with age. Changes in the determinants of loneliness during adolescence were investigated for grade 8, grade 11, and university students. Subjects (N=410) completed a written questionnaire which included ten items from the UCLA Loneliness Scale, the…

  5. Punishing adolescents

    DEFF Research Database (Denmark)

    Ryberg, Jesper

    2014-01-01

    Should an adolescent offender be punished more leniently than an adult offender? Many theorists believe the answer to be in the affirmative. According to the diminished culpability model, adolescents are less mature than adults and, therefore, less responsible for their wrongdoings and should...

  6. Psychological sequelae of the station nightclub fire: Comparing survivors with and without physical injuries using a mixed-methods analysis.

    Directory of Open Access Journals (Sweden)

    Nhi-Ha T Trinh

    Full Text Available Surveying survivors from a large fire provides an opportunity to explore the impact of emotional trauma on psychological outcomes.This is a cross-sectional survey of survivors of The Station Fire. Primary outcomes were post-traumatic stress (Impact of Event Scale - Revised and depressive (Beck Depression Inventory symptoms. Linear regression was used to examine differences in symptom profiles between those with and without physical injuries. The free-response section of the survey was analyzed qualitatively to compare psychological sequelae of survivors with and without physical injuries.104 participants completed the study survey; 47% experienced a burn injury. There was a 42% to 72% response rate range. The mean age of respondents was 32 years, 62% were male, and 47% experienced a physical injury. No significant relationships were found between physical injury and depressive or post-traumatic stress symptom profiles. In the qualitative analysis, the emotional trauma that survivors experienced was a major, common theme regardless of physical injury. Survivors without physical injuries were more likely to experience survivor guilt, helplessness, self-blame, and bitterness. Despite the post-fire challenges described, most survivors wrote about themes of recovery and renewal.All survivors of this large fire experienced significant psychological sequelae. These findings reinforce the importance of mental health care for all survivors and suggest a need to understand factors influencing positive outcomes.

  7. Tibial lengthening over humeral and tibial intramedullary nails in patients with sequelae of poliomyelitis: a comparative study.

    Science.gov (United States)

    Chen, Daoyun; Chen, Jianmin; Jiang, Yao; Liu, Fanggang

    2011-06-01

    Leg discrepancy is common after poliomyelitis. Tibial lengthening is an effective way to solve this problem. It is believed lengthening over a tibial intramedullary nail can provide a more comfortable lengthening process than by the conventional technique. However, patients with sequelae of poliomyelitis typically have narrow intramedullary canals allowing limited space for inserting a tibial intramedullary nail and Kirschner wires. To overcome this problem, we tried using humeral nails instead of tibial nails in the lengthening procedure. In this study, we used humeral nails in 20 tibial lengthening procedures and compared the results with another group of patients who were treated with tibial lengthening over tibial intramedullary nails. The mean consolidation index, percentage of increase and external fixation index did not show significant differences between the two groups. However, less blood loss and shorter operating time were noted in the humeral nail group. More patients encountered difficulty with the inserted intramedullary nail in the tibial nail group procedure. The complications did not show a statistically significant difference between the two techniques on follow-up. In conclusion, we found the humeral nail lengthening technique was more suitable in leg discrepancy patients with sequelae of poliomyelitis.

  8. The school inclusion and use of assistive technology with myelomeningocele sequelae students: a view of the teachers

    Directory of Open Access Journals (Sweden)

    Caroline Penteado Assis

    2011-06-01

    Full Text Available Myelomeningocele is a congenital malformation that affects the fetus during pregnancy. It can causes numerous consequences for the development of the child and consequently in their schooling process. So, there are several challenges that can be experienced by these children in their inclusion at school. The use of assistive technology in the school context has been implanted with goal to high from the functional abilities of these students. In Brazil are conducted a lot of studies to know the reality of children with myelomeningocele. Therefore, the goal of this study was to investigate, from the teacher ́s perspective of regular and multifunctional class, as was the process of schooling for students with myelomeningocele sequelae and resource utilization of assistive technology in the school context. The participants of this research were seven teachers and four students with myelomeningocele sequels enclosed in regular scholl.The researcher confectioned the instruments used in interviews. Data were analyzed using content of interview analysis. The results reveal that there are present challenges for inclusion of students with myelomeningocele sequelae and that teachers did not use assistive technology resources at school. It is considered that for the real practice of educational inclusion of these students the knowledge about meningomyelocele and various technologies that can be used in the school context must be published.

  9. A meta-analysis of the neuropsychological sequelae of chemotherapy-only treatment for pediatric acute lymphoblastic leukemia.

    Science.gov (United States)

    Peterson, Catherine C; Johnson, Courtney E; Ramirez, Lisa Y; Huestis, Samantha; Pai, Ahna L H; Demaree, Heath A; Drotar, Dennis

    2008-07-01

    Mixed findings on the neuropsychological sequelae of chemotherapy-only treatment for pediatric acute lymphoblastic leukemia (ALL), without radiation, indicate the need for a comprehensive meta-analytic review. The purpose of the current study was to conduct a meta-analysis assessing neuropsychological and academic functioning differences between children with ALL treated solely with chemotherapy and comparison groups. Thirteen articles met inclusion criteria for the meta-analysis and were analyzed using a random effects model, weighted least squares methods. Mean effect sizes were significantly different from zero for multiple domains of intelligence and academic achievement; processing speed; verbal memory; and some aspects of executive functioning and fine motor skills, indicating worse functioning in ALL survivors. Effect sizes for visual-motor skills and visual memory were not significantly different from zero. Results support the presence of neuropsychological and academic sequelae for ALL survivors treated solely with chemotherapy and highlight the need for ongoing follow-up of children with ALL using a standardized neuropsychological test battery and research methodology. (c) 2008 Wiley-Liss, Inc.

  10. [Anemia and limping in a vegetarian adolescent].

    Science.gov (United States)

    Chiron, R; Dabadie, A; Gandemer-Delignieres, V; Balençon, M; Legall, E; Roussey, M

    2001-01-01

    A vegan diet in the child and adolescent can induce severe bone sequelae by rickets and osteomalacia and megaloblastic anemia by cobalamin deficiency. A 15-year-old adolescent was hospitalized because of lameness and pallor. The lameness was explained by femoral epiphysiolysis caused by rickets with severe hypocalcemia. The pallor, jaundice and splenomegalia were due to cobalamin-deficiency megaloblastic anemia. A prolonged supplemental diet with calcium, vitamins D and B12 as well as orthopedic treatment stabilized the bone lesions. The megaloblastic anemia was cured by parenteral cobalamin. The adolescent and his brother were victims of a diet imposed by a cult and a lack of care due to their parents refusing that a vegan diet was the cause of the deficient pathology. Penal proceedings led to the incarceration of the parents and to the placement of the children. Deficiencies in calcium and vitamins D and B12 may be severe in a child's development with a vegan diet. This case report reveals the social and legal problems of an inappropriate diet in infancy imposed by parents who are followers of a fundamentalist church. Beyond the management of children in cults, health professionals have to prevent, screen and supplement the deficient diet.

  11. Pediatric and adolescent applications of the Taylor Spatial Frame.

    Science.gov (United States)

    Paloski, Michael; Taylor, Benjamin C; Iobst, Christopher; Pugh, Kevin J

    2012-06-01

    Limb deformity can occur in the pediatric and adolescent populations from multiple etiologies: congenital, traumatic, posttraumatic sequelae, oncologic, and infection. Correcting these deformities is important for many reasons. Ilizarov popularized external fixation to accomplish this task. Taylor expanded on this by designing an external fixator in 1994 with 6 telescoping struts that can be sequentially manipulated to achieve multiaxial correction of deformity without the need for hinges or operative frame alterations. This frame can be used to correct deformities in children and has shown good anatomic correction with minimal morbidity. The nature of the construct and length of treatment affects psychosocial factors that the surgeon and family must be aware of prior to treatment. An understanding of applications of the Taylor Spatial Frame gives orthopedic surgeons an extra tool to correct simple and complex deformities in pediatric and adolescent patients.

  12. Stages of Adolescence

    Science.gov (United States)

    ... Español Text Size Email Print Share Stages of Adolescence Page Content Article Body Adolescence, these years from puberty to adulthood, may be roughly divided into three stages: early adolescence, generally ages eleven to fourteen; middle adolescence, ages ...

  13. Intervenção fisioterapêutica nas sequelas de drenagem linfática manual iatrogênica: relato de caso Physical therapy in sequelae of iatrogenic manual lymphatic drainage: a case report

    Directory of Open Access Journals (Sweden)

    Rogério Eduardo Tacani

    2011-06-01

    Full Text Available Atualmente, a drenagem linfática manual (DLM é um dos recursos de grande destaque no tratamento de edemas, linfedemas e condições inestéticas, porém, na prática clínica têm-se observado sua aplicação de forma iatrogênica. Os objetivos deste relato de caso foram apontar as sequelas da aplicação iatrogênica da DLM, em uma jovem caucasiana, e verificar os efeitos da intervenção fisioterapêutica no tratamento dessas. Voluntária de 27 anos, apresentava-se com uma equimose importante na região lateral da coxa esquerda (28 x 9,5 cm, telangiectasias, microvaricosidades e petéquias em ambas as coxas e pernas, dor de forte intensidade e edema, após ter se submetido a um procedimento manual iatrogênico com finalidade estética há dois dias. As condutas fisioterapêuticas adotadas foram: Ultrassom 3 MHz, pulsado (2 ms on, 8 ms off, 0,4 W/cm² SATP na região da equimose e DLM (Método Leduc durante 20 minutos, na coxa esquerda. Foram realizadas nove sessões até a alta no 16º dia pós-lesão, observando-se apenas a redução gradativa da dor e da equimose. Verificou-se a efetividade da intervenção fisioterapêutica em apenas algumas das sequelas provocadas pela iatrogenia, sem desconsiderar que a remissão espontânea dos sinais e sintomas também pode ter contribuído para tal. Destaca-se a importância de conscientizar os fisioterapeutas que atuam com este procedimento para que o aplique de forma adequada, evitando tais iatrogenias.Recently, the manual lymphatic drainage (MLD is an important resource in the treatment of edemas, lymphedemas, and other unaesthetic conditions. However, problems caused by the incorrect application of this therapy have been observed in the clinical practice. The aims of this case report were to describe sequelae resulting from the negligent application of MLD on a young patient, and to determine the effects of physical therapy on the treatment of sequelae. A 27-year-old Caucasian woman presented

  14. Podem as escalas preditivas de mortalidade ser utilizadas para prever a ocorrência de sequelas nos sobreviventes de cuidados intensivos?

    OpenAIRE

    Oom, Paulo

    2014-01-01

    Introdução: Não existem disponíveis escalas capazes de prever a ocorrência de sequelas nos sobreviventes de cuidados intensivos.Objectivos: Foram objectivos deste estudo avaliar o desempenho das escalas preditivas de mortalidade na previsão da ocorrência de sequelas nas crianças que sobrevivem ao internamento em unidades de cuidados intensivos. Métodos: Estudo prospectivo que decorreu numa unidade de cuidados intensivos de pediatria de um hospital universitário durante um período de 21 meses....

  15. Adolescence depressions

    National Research Council Canada - National Science Library

    Matot, J P

    2009-01-01

    This article considers the depressive problematics emerging during adolescence in the frame of the transformations that characterize this period of life, with a focus on the interference of socio-cultural dimensions...

  16. Adolescent Sexuality.

    Science.gov (United States)

    Sharpe, Thomasina H.

    2003-01-01

    This article offers a medical and psychosocial perspective of adolescent sexual development. Sub-types of sexual development are discussed as well as treatment implications for allied health providers. (Contains 38 references.) (Author)

  17. Hydrokinesitherapy program using the Halliwick method on strength endurance and flexibility in a person with poliomyelitis sequelae.

    Science.gov (United States)

    Ochoa Martínez, Paulina Yesica; Hall Lopez, Javier Arturo; Mateos Valenzuela, Adriana Griselda

    2014-09-12

    This case study attempts to determine the effect of a hydrokinesitherapy program by means of the Halliwick method on physical fitness in a female aged 35 years with poliomyelitis sequelae. The intervention followed sixteen weeks of hydrokinesitherapy during 70 minutes, five times a week, where we carried out exercises from the Halliwick method. There was an assessment both before and after the application. Strength endurance and flexibility were determined according to a senior fitness test protocol. The results showed positive improvements when carrying out the exercises from the Halliwick method and the percentage change (Δ%) of strength endurance increase 361.5% in the right arm and 300% in the left arm. Flexibility increased 2 cm in the right shoulder and 10 cm in the left shoulder. In conclusion the subject was able to improve the performance of Halliwick exercises while showing an increase in strength endurance and flexibility.

  18. Frequency, imaging findings, risk factors, and long-term sequelae of distal clavicular osteolysis in young patients

    Energy Technology Data Exchange (ETDEWEB)

    Roedl, Johannes B.; Nevalainen, Mika; Gonzalez, Felix M.; Morrison, William B.; Zoga, Adam C. [Thomas Jefferson University Hospital, Thomas Jefferson University, Division of Musculoskeletal Imaging and Interventions, Department of Radiology, Philadelphia, PA (United States); Dodson, Christopher C. [Thomas Jefferson University Hospital, Rothman Institute, Sidney Kimmel Medical College at Thomas Jefferson University, Division of Sports Medicine, Department of Orthopedic Surgery, Philadelphia, PA (United States)

    2015-05-01

    Atraumatic distal clavicular osteolysis (DCO) has been described in adult male weightlifters. Our purpose was to investigate the frequency, magnetic resonance imaging (MRI) characteristics, risk factors, and long-term sequelae of DCO in young patients. Individuals with atraumatic DCO were identified in a retrospective review of 1,432 consecutive MRI shoulder reports in patients between 13 and 19 years of age. MRI findings of DCO, association with athletic activity, short-term clinical outcome after 3-6 months, and long-term clinical and MRI outcome after 2 years were analyzed. A pre-MRI questionnaire assessed the patients' athletic history including overhead activity and weightlifting. At a mean age of 15.9 years, 6.5 % (93/1432) of patients had atraumatic DCO, and 24 % were females. The combination of an overhead sport (basketball, volleyball, tennis, swimming) and supplemental weight training was a risk factor for DCO (odds ratio = 38, p = 0.01). Ninety-three percent of patients responded to conservative therapy. On follow-up imaging, 71 % of DCO patients had acromioclavicular (AC) joint osteoarthritis (vs. 35 % in controls, p = 0.006); 79 % had flattening of the distal clavicle and interval widening of the AC joint to a mean of 5.0 mm (compared to 2.4 mm in controls, p < 0.001). Severity of DCO edema was associated with pain (p < 0.02) at initial presentation and with AC joint osteoarthritis (p = 0.004) on follow-up. In athletic teenagers, the combination of weightlifting and overhead activity is a risk factor for atraumatic DCO, and females are affected in 24 %. Long-term sequelae include widening of the AC joint and AC joint osteoarthritis. (orig.)

  19. [Lipomodelling for correction of breast conservative treatment sequelae. Medicolegal aspects. Expert opinion on five problematic clinical cases].

    Science.gov (United States)

    Gosset, J; Flageul, G; Toussoun, G; Guérin, N; Tourasse, C; Delay, E

    2008-04-01

    In our unit, breast cancer patients suffering mild sequelae of conservative cancer treatment receive fat transfer (lipomodelling), following a precise protocol, based on mammographic and ultrasound examinations and MRI. Available data do not seem to indicate any deleterious impact on patient outcome, notably in view of radiological images, but recurrence (or rather occurrence of new ipsilateral or contralateral cancer) is frequent. The correlation between new or recurrent breast cancer and lipomodelling is high; misinterpretations are possible and frequently arise. The present paper is a description of five complex clinical cases and a discussion of the medicolegal issues that may possibly arise; it also provides tentative expert evaluation of the cases. Clinical findings are reported and analyzed. The second step is a discussion of the radiological impact of lipomodelling, and of the problems caused by the transfer of potentially malignant cells when no preoperative diagnosis of recurrence is made; the morphological and esthetic benefits of the method are described, as well as the potential beneficial impact of fat transfer, notably associated with lower breast density and injections of fat stem cells. Our conclusion is that specialized radiologists, as well as plastic surgery and oncology experts should address the question of fat transfer in operated breast cancer patients and give their reasoned opinion about potentially litigious cases. This would help minimize or solve the conflicts between patients, doctors and experts. Establishing common ground between the different stakeholders would allow the development of the technique, as lipomodelling is, according to our experience, a tremendous advance in the treatment of sequelae from conservative breast cancer surgery.

  20. Effectiveness of clinical assessment in Spanish forensic practice: detecting malingered psychological sequelae in victims of intimate partner violence

    Directory of Open Access Journals (Sweden)

    Miguel Ángel Soria

    2011-03-01

    Full Text Available Background and Objectives: According to Spanish legislation, the psychological harm suffered by the victim of a criminal act is determined by assessing its impact on the victim's mental state. Usually, the victim's pain and suffering is estimated by administering clinical scales. The aim of the present study was to explore the effectiveness of psychopathological assessment using commonly used scales in clinical practice and whose results are presented as legal evidence in a forensic context in order to detect malingered psychological sequelae (anxiety, depression and low self-esteem in victims of intimate partner violence in forensic contexts. Methods: In the present study three scales based in a clinical setting and regularly used in a forensic context were administered (BDI, STAI and Rosenberg to assess malingering of symptoms. The sample comprised 66 women: 36 students, and 30 real victims. The non-clinical sample was evaluated twice: the first time they gave sincere responses, and the second time they were instructed to answer as if they were victims. The real victims underwent testing in a forensic context. Results and Conclusions: The results of our research show that, even without previous knowledge of the scales, people can distort the test results by malingering symptoms that are normally accepted as sequelae of intimate partner violence, especially depression and low self-esteem; however, the results for anxiety, were less homogeneous. Although these tests are used extensively in clinical psychology, our study confirms that, just by themselves, they are not a reliable source of information in a forensic context.

  1. Gender minority social stress in adolescence: disparities in adolescent bullying and substance use by gender identity.

    Science.gov (United States)

    Reisner, Sari L; Greytak, Emily A; Parsons, Jeffrey T; Ybarra, Michele L

    2015-01-01

    Bullying and substance use represent serious public health issues facing adolescents in the United States. Few large-sample national studies have examined differences in these indicators by gender identity. The Teen Health and Technology Study (N = 5,542) sampled adolescents ages 13 to 18 years old online. Weighted multivariable logistic regression models investigated disparities in substance use and tested a gender minority social stress hypothesis, comparing gender minority youth (i.e., who are transgender/gender nonconforming and have a gender different from their sex assigned at birth) and cisgender (i.e., whose gender identity or expression matches theirs assigned at birth). Overall, 11.5% of youth self-identified as gender minority. Gender minority youth had increased odds of past-12-month alcohol use, marijuana use, and nonmarijuana illicit drug use. Gender minority youth disproportionately experienced bullying and harassment in the past 12 months, and this victimization was associated with increased odds of all substance use indicators. Bullying mediated the elevated odds of substance use for gender minority youth compared to cisgender adolescents. Findings support the use of gender minority stress perspectives in designing early interventions aimed at addressing the negative health sequelae of bullying and harassment.

  2. Anestesia para paciente portadora de múltiplas afecções endócrinas: relato de caso Anestesia para paciente portadora de múltiples afecciones endocrinas: relato de caso Anesthesia in a patient with multiple endocrine abnormalities: case report

    Directory of Open Access Journals (Sweden)

    Renato Toledo Maciel

    2008-04-01

    -operatório para que se evitem ressecções incompletas do tumor. A multiplicidade dos desafios em um só paciente exige do anestesiologista o conhecimento de cada obstáculo e suas interações, traçando estratégias para contorná-los.JUSTIFICATIVA Y OBJETIVOS: El insulinoma es un tumor endocrino pancreático más común. Pude estar asociado a neoplasias endocrinas múltiples (NEM. Se ha relatado el caso de paciente con disturbios endocrinos múltiplos que, sin embargo, no se encuadra en síndromes (NEM ya conocidas, y con particularidades clínico anestésicas que influyeron en el manejo de su anestesia. RELATO DEL CASO: Paciente femenina, 23 años, con hipoglicemias de difícil control asociadas a la enfermedad de Cushing y prolactinoma, sin síntomas compresivos hipofisarios, y con estudios de tiroides y de paratiroides sin alteraciones. La investigación laboratorial encontró masa retroperitoneal de etiología desconocida que, relacionada con la situación clínica, conllevó a la hipótesis de insulinoma. Decía que era testigo de Jeová. La propuesta terapéutica era biopsia de la masa por videolaparoscopía y enucleación del insulinoma. Cuando se le hizo el examen, se le encontró obesa, con dientes protuberantes, Mallampati 3 y síntomas de apnea obstructiva del sueño. En los exámenes laboratoriales, el resultado relevante fue el hematócrito de 58%. Recibió midazolan (7,5 mg y clonidina (200 µg vía oral, como medicación preanestésica. La inducción anestésica fue realizada con fentanil (150 µg, clonidina (90 µg, propofol (150 µg y pancuronio (8 mg, siendo realizada la intubación traqueal sin problemas. Se establecieron el acceso venoso central y el monitoreo invasivo de la presión. Se mantuvo infusión de glicosis al 5% con electrolitos y se monitoreó la glicemia capilar a cada 30 minutos, que no mostró episodios de hipoglicemia durante la operación. Se mantuvo hemodinámicamente estable incluso durante el neumoperitoneo. En el postoperatorio present

  3. Exposure to Childhood Poverty and Mental Health Symptomatology in Adolescence: A Role of Coping Strategies.

    Science.gov (United States)

    Kim, Pilyoung; Neuendorf, Cynthia; Bianco, Hannah; Evans, Gary W

    2016-12-01

    Childhood poverty is associated with stress dysregulation which contributes to psychological illness in later ages. The adverse effects of childhood poverty on stress regulation may be mediated in part by the use of disengaging strategies to cope with stress. However, the relations among childhood poverty, coping strategies and psychopathology throughout childhood to adolescence have not been explored. This prospective, longitudinal study included 185 low- and middle-income adolescents at age 17. Chronic exposure to poverty from birth to early adolescence (age 13) was prospectively associated with increases in the use of disengagement versus engagement coping four years later. Increased use of disengagement coping between the ages of 13 and 17 explained the indirect link between poverty exposure since birth and both externalizing and internalizing symptoms at age 17. The findings provide evidence for a coping pathway underlying the link between prolonged exposure to childhood poverty and mental health sequelae. Copyright © 2015 John Wiley & Sons, Ltd.

  4. A brief primer on acne therapy for adolescents with skin of color.

    Science.gov (United States)

    Silverberg, Nanette B

    2013-07-01

    The majority of adolescents with skin of color in the United States and other westernized civilizations develop acne vulgaris. Indigenous populations of children and teenagers with skin of color may not develop acne when raised on a paleolithic diet, suggesting the Western diet is the rudiment of acne vulgaris. Differences exist in the presentation of and therapy for acne in teenagers with skin of color, largely due to the increased risk for hyperpigmentation, scarring, and keloid formation, as well as style- and skin care-related exacerbating factors. The primary goal of acne therapy in adolescents with skin of color is the prevention of long-term sequelae such as keloid formation. This article provides a brief overview of the treatment of acne vulgaris in adolescents with skin of color.

  5. The Prospective Contribution of Childhood Maltreatment to Low Self-Worth, Low Relationship Quality, and Symptomatology Across Adolescence: A Developmental-Organizational Perspective

    OpenAIRE

    Flynn, Megan; Cicchetti, Dante; Rogosch, Fred

    2014-01-01

    This research investigated the prospective contribution of childhood maltreatment to low self-worth, low relationship quality, and symptoms during adolescence. Further, the stability and cross-lagged effects of these sequelae of maltreatment were examined over time. History of maltreatment during childhood was obtained, and youth (407 maltreated, 228 nonmaltreated; 376 males, 259 females) completed two subsequent assessments spaced approximately two years apart during early-mid and mid-late a...

  6. Does the piezoelectric surgical technique produce fewer postoperative sequelae after lower third molar surgery than conventional rotary instruments? A systematic review and meta analysis.

    Science.gov (United States)

    Al-Moraissi, E A; Elmansi, Y A; Al-Sharaee, Y A; Alrmali, A E; Alkhutari, A S

    2016-03-01

    A systematic review and meta-analysis was conducted to answer the clinical question "Does the piezoelectric surgical technique produce fewer postoperative sequelae after lower third molar surgery than conventional rotary instruments?" A systematic and electronic search of several databases with specific key words, a reference search, and a manual search were performed from respective dates of inception through November 2014. The inclusion criteria were clinical human studies, including randomized controlled trials (RCTs), controlled clinical trials (CCTs), and retrospective studies, with the aim of comparing the piezoelectric surgical osteotomy technique to the standard rotary instrument technique in lower third molar surgery. Postoperative sequelae (oedema, trismus, and pain), the total number of analgesics taken, and the duration of surgery were analyzed. A total of nine articles were included, six RCTs, two CCTs, and one retrospective study. Six studies had a low risk of bias and three had a moderate risk of bias. A statistically significant difference was found between piezoelectric surgery and conventional rotary instrument surgery for lower third molar extraction with regard to postoperative sequelae (oedema, trismus, and pain) and the total number of analgesics taken (P=0.0001, P=0.0001, Ppiezoelectric osteotomy group (Ppiezoelectric surgery significantly reduced the occurrence of postoperative sequelae (oedema, trismus, and pain) and the total number of analgesics taken compared to the conventional rotary instrument technique in lower third molar surgery, but required a longer surgery time.

  7. The Role of Reverse Shoulder Arthroplasty in Management of Proximal Humerus Fractures with Fracture Sequelae: A Systematic Review of the Literature

    Science.gov (United States)

    Holton, James; Yousri, Tahir; Arealis, George; Levy, Ofer

    2017-01-01

    Fracture sequelae of the proximal humerus poses a complex management decision due to the frequent deformity and its consequences on the peri-articular soft tissues. These patients are frequently elderly with significant medical comorbidities. Due to the age of the patient there is frequently rotator cuff deficiency and therefore the reverse shoulder arthroplasty (RSA) becomes the arthroplasty of choice. We have performed a systematic review of the literature and report nine studies presenting RSA for the treatment of fracture sequelae of the proximal humerus. It is clear that RSA can improve the range of movement and function following proximal humerus fracture sequelae. However, there is a risk of significant complications including dislocation (16.7%), infection (6.7%), intra-operative fracture (3%) and neurological injury (2.6%). There is a need to invest in future prospective comparative studies and randomised trials to further test RSA in fracture sequelae patients. This will provide us with information regarding the longevity of different prosthesis, outcomes and cost-effectiveness of treatment. PMID:28286622

  8. The role of reverse shoulder arthroplasty in management of proximal humerus fractures with fracture sequelae: a systematic review of the literature

    Directory of Open Access Journals (Sweden)

    James Holton

    2017-02-01

    Full Text Available Fracture sequelae of the proximal humerus poses a complex management decision due to the frequent deformity and its consequences on the peri-articular soft tissues. These patients are frequently elderly with significant medical comorbidities. Due to the age of the patient there is frequently rotator cuff deficiency and therefore the reverse shoulder arthroplasty (RSA becomes the arthroplasty of choice. We have performed a systematic review of the literature and report nine studies presenting RSA for the treatment of fracture sequelae of the proximal humerus. It is clear that RSA can improve the range of movement and function following proximal humerus fracture sequelae. However, there is a risk of significant complications including dislocation (16.7%, infection (6.7%, intra-operative fracture (3% and neurological injury (2.6%. There is a need to invest in future prospective comparative studies and randomised trials to further test RSA in fracture sequelae patients. This will provide us with information regarding the longevity of different prosthesis, outcomes and costeffectiveness of treatment.

  9. Hepatic and extra-hepatic sequelae, and prevalence of viral hepatitis C infection estimated from routine data in at-risk groups

    Directory of Open Access Journals (Sweden)

    Sorge Chiara

    2010-04-01

    Full Text Available Abstract Background Concerns about the hepatitis C virus (HCV are due to the high risk of chronic liver disease and poor treatment efficacy. Synthesizing evidence from multiple data sources is becoming widely used to estimate HCV-infection prevalence. This paper aims to estimate the prevalence of HCV infection, and the hepatic and extrahepatic sequelae in at-risk groups, using routinely collected data in the Lazio region, Italy. Methods HCV laboratory surveillance and dialysis, hospital discharge, and drug-user registers were used as information sources to identify at-risk groups and to estimate HCV prevalence and sequelae. Full name and birth date were used as linkage keys for the various health registries. Prevalence was estimated as the percentage of cases within the general population and the at-risk groups, with 95% confidence intervals (95% CI from 1997 to 2001. The risk of sequelae was estimated through a follow-up of hospital discharges up to December 31, 2004 and calculated as the prevalence ratio in HCV-positive and HCV-negative people, within each at-risk group, with 95% CI. Results There were 65,127 HCV-infected people in the study period; the prevalence was 1.24% (95%CI = 1.23%-1.25% in the whole population, higher in males and older adults. Drug users (35.1%; 95%CI = 34.6-35.7 and dialysis patients (21.1%; 95%CI = 20.2%-22.0% showed the highest values. Medical procedures with little exposure to blood resulted in higher estimates, ranging between 1.3% and 3.4%, which was not conclusively attributable to the surgical procedures. Cirrhosis, hepatocellular carcinoma and encephalopathy were the most frequent hepatic sequelae; cryoglobulinaemia and non-Hodgkin's lymphoma were the most frequent extrahepatic sequelae. Conclusions Synthesising data from multiple routine sources improved estimates of HCV prevalence and sequelae in dialysis patients and drug users, although prevalence validity should be assessed in survey and sequelae need a

  10. Adolescent loneliness.

    Science.gov (United States)

    Williams, E G

    1983-01-01

    The purpose of this study was to investigate the phenomenon of loneliness in delinquent adolescents with regard to types of delinquency offenses committed, demographic characteristics, and personality characteristics in the areas of interpersonal needs for inclusion, control, and affection. The types of delinquency offenses were categorized as burglary, runaway, drugs, assault, and incorrigible. The demographic variables examined were age, sex, race, family rank or birth order, family structure in terms of parental presence, family income level, religion, and geographic locale. A sample of 98 adolescents was obtained from juvenile detention facilities in three metropolitan areas in the United States. Subjects ranged in age from 12 to 18. Subjects were asked to complete the Loneliness Questionnaire as a self-reported measure of loneliness. Subjects also provided information about themselves relative to demographic characteristics and completed the FIRO-B Questionnaire, which measured interpersonal needs for inclusion, control, and affection. The results revealed no significant differences with regard to any of the demographic variables when the effect of each was considered alone. However, there was a significant effect on loneliness by income when considered jointly with other demographic variables. Adolescents from the middle income group expressed more loneliness than those from the upper and lower income groups. No significant differences were observed with regard to personality characteristics related to interpersonal needs for inclusion and affection, but delinquent adolescents with medium to high needs for control indicated significantly more feelings of loneliness than delinquent adolescents with low needs for control.

  11. Lesões sequelares na laringe em pacientes com paracoccidiodomicose Sequelae lesions in the larynxes of patients with paracoccidioidomycosis

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    Jose Mauricio Lopes Neto

    2011-02-01

    Full Text Available A Paracoccidioidomicose (PCM é uma doença sistêmica que em sua forma sequelar se caracteriza por manifestações clínicas relacionadas às alterações anatômicas ou funcionais de órgãos e sistemas comprometidos no período de estado. OBJETIVO: Descrever as alterações anatômicas e funcionais laríngeas sequelares em pacientes com paracoccidioidomicose. MATERIAL E MÉTODOS: Estudo retrospectivo, sendo avaliados 49 pacientes do sexo masculino, na faixa etária de 30 a 60 anos, entre 1999 a 2004, com diagnóstico de PCM em acompanhamento pela disciplina de Moléstias Infecciosas e Parasitárias, confirmado pela demonstração do fungo em escarro, exame citológico ou histopatológico. RESULTADOS: As pregas vocais foram a estrutura laríngea mais afetada, em 67% dos pacientes verificaram-se alterações. A epiglote estava acometida em 55% dos casos. As pregas ariepiglóticas tinham modificações em 53% dos pacientes. As pregas vestibulares estavam alteradas em 46% dos casos. Em 40% dos casos verificaram-se alterações em aritenoides. Na fonação, 28% tinham limitação ao movimento das cordas vocais, paresia unilateral ocorreu em 4% casos. Em 24% havia restrição da luz supraglótica e 4% tinham estenose glótica, sendo que 2% precisaram de traqueotomia. CONCLUSÃO: As lesões sequelares na laringe devido à infecção pelo P. brasilienses são extensas e causam restrições funcionais na maioria dos casos.Paracoccidioidomycosis (PCM is a systemic disease that in its aftermath form is characterized by clinical manifestations related to anatomic or functional sequelae of organs and systems affected during the period of state. AIM: To describe the anatomical and functional sequelae in patients with treated laryngeal PCM. MATERIALS AND METHODS: Retrospective study. We reviewed the charts from of 49 male patients, aged between 30 to 60 years, diagnosed with laryngeal PCM during the period of 1999 to 2004. In all patients the diagnosis of

  12. Avaliação espirométrica de doentes com sequela de tuberculose submetidos à lobectomia

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    Elias Amorim

    Full Text Available OBJETIVO: Avaliar a espirometria no pré e pós-operatório de doentes com sequela de tuberculose, submetidos à lobectomia. MÉTODOS: Foram selecionados 20 doentes, com idade entre 15 e 56 anos, de ambos os sexos, com história pregressa de tratamento de tuberculose, apresentando infecção de repetição ou hemoptises. Foram submetidos à lobectomia pulmonar. O tempo de tratamento da tuberculose foi seis meses e o aparecimento dos sintomas entre um e 32 anos. Foram avaliadas a capacidade vital (CV, a capacidade vital forçada (CVF, o volume expiratório forçado (VEF1, o VEF1/CVF, o fluxo expiratório forçado (FEF e o pico de fluxo expiratório (PFE após o primeiro, terceiro e sexto meses em relação ao pré-operatório. O nível de significância (á aplicado em todos os testes foi 5%, ou seja, considerou-se significativo quando p<0,05. RESULTADOS: As Médias encontradas foram as seguintes: Capacidade Vital (CV Pré-operatória-2,83 ; 1º PO 2,12; 3º PO 2,31; 6º PO 2,43. Capacidade Vital Forçada (CVF Pré-operatória- 2,97; 1º PO 2,21; 3º PO 2,35; 6º PO 2,53. Volume Expiratório no 1º Segundo (VEF1 Pré-operatório 2,23; 1º PO 1,75; 3º PO 1,81; 6º PO 1,97. Houve diminuição acentuada das funções respiratórias no primeiro mês de pós-operatório, porém houve melhora dos parâmetros a partir do terceiro mês, com progressivo aumento até o sexto mês de pós-operatório. CONCLUSÃO: Não houve recuperação dos parâmetros espirométricos, comparados aos do pré operatório, após seis meses de pós-operatório nos pacientes com sequela de tuberculose submetidos à lobectomia.

  13. Evaluation of some oral postradiotherapy sequelae in patients treated for head and neck tumors; Avaliacao de algumas sequelas bucais pos-radioterapia em pacientes tratados de neoplasias de cabeca e pescoco

    Energy Technology Data Exchange (ETDEWEB)

    Rubira, Cassia Maria Fischer; Devides, Nadia Juliana; Ubeda, Liliane Torsani; Lauris, Jose Roberto; Rubira-Bullen, Izabel Regina Fischer; Damante, Jose Humberto [University of Sao Paulo, Bauru, SP (Brazil). School of Dentistry. Stomatology Dept.; Bortolucci Junior, Antonio Geraldo [Amaral Carvalho Hospital, Jau, SP (Brazil)]. E-mail: damante@fob.usp.br

    2007-07-01

    The aim of this study was to evaluate the oral sequelae of radiotherapy in patients treated between 1999 and 2003 for head and neck tumors. One-hundred patients (24 women, 76 men) ranging in age from 30 to 83 years (mean 59.2 years) were examined. Time since radiotherapy ranged from 1 to 72 months (mean 28 months). The total mean radiation dose received by the patients was 5,955 cGy. The evaluation protocol included anamnesis, intraoral and extraoral examination, measurement of stimulated salivary flow and salivary pH. Symptoms reported by the patients included dry mouth (68%), dysphagia (38%), and dysgeusia (30%). In 64% of the patients, the mean stimulated salivary flow rate was less than 0.7 ml/min. The mean salivary pH was 6.97 ({+-} 0.714). Stimulated salivary flow increased with increasing postradiotherapy time (p < 0.05). The prevalence of mucositis was associated with higher radiation doses (p < 0.05), and the prevalence of atrophic candidiasis was related to a longer post-treatment period (p < 0.05). Two cases of recurrence of the primary tumor were detected during the study. The main effect of radiotherapy in the head and neck region was a reduction of the salivary flow rate, even though our study demonstrated that there was a modest late improvement of the salivary flow. (author)

  14. Treating Children and Adolescents

    Science.gov (United States)

    ... Children and Adolescents Go Back Treating Children and Adolescents Email Print + Share For the most part, the ... tailored, based upon the child's weight. Children and adolescents are moving through a period of physical and ...

  15. Adolescent growth and development.

    Science.gov (United States)

    Chulani, Veenod L; Gordon, Lonna P

    2014-09-01

    Adolescence is a developmental stage defined by physical and psychosocial maturation. This article reviews normal pubertal development and the evaluation and management of adolescents with suspected pubertal abnormalities and provides an overview of adolescent psychosocial development.

  16. Adolescent homosexuality.

    Science.gov (United States)

    Stronski Huwiler, S M; Remafedi, G

    1998-01-01

    Homosexuality has existed in all civilizations, but societal disapproval and cultural taboos have negatively influenced its recognition. A significant percentage of youths identify themselves as homosexual, and even more experience sex with the same sex or are confused about sexual feelings. A unifying etiological theory attributes the expression of sexual orientation to genes that shape the central nervous system's development, organization, and structure via prenatal sex steroids. Environmental factors may influence the expression of genetic potential. Several models of psychosocial development describe initial stages of awareness and confusion about same-sex attractions, followed by acknowledgement of homosexuality, disclosure to others, and eventual integration of sexual identity into a comprehensive sense of self. Stressors related to isolation, stigma, and violence may predispose homosexual adolescents to impaired social, emotional, and physical health, resulting in depression and suicide, school problems, substance abuse, running away eating disorders, risky sexual behavior, and illegal conduct. As with all adolescents, the overall goals in the care of homosexual youth are to promote normal adolescent development, social and emotional well-being, and physical health. A comprehensive, multidisciplinary approach is required to address medical, mental health, and psychosocial issues within the context of the adolescents' community and culture.

  17. [The catamnesis of patients with protracted forms of trichotillomania starting in childhood and adolescence].

    Science.gov (United States)

    Shevchenko, Iu S; Demidovich, T V

    1993-01-01

    Sequelae of severe trichotillomania initiating in childhood and adolescence were studied in 26 patients aged 21-32. A mean prospective follow-up lasted for 13 years. Thirteen patients were qualified as healthy. In the rest trichotillomania remained the main symptom of the illness, in 9 patients the progressive disease became the basis for secondary psychopathies, pathocharacterological personality of deficiency type. The following factors reliably affecting the prognosis were revealed: residual-organic origin of trichotillomania, intensity, generalization and polymorphism of the habit, persistence of the syndrome development, severity of vegetative component, late therapy start.

  18. Anabolic-androgenic steroid exposure during adolescence and aggressive behavior in golden hamsters.

    Science.gov (United States)

    Melloni, R H; Connor, D F; Hang, P T; Harrison, R J; Ferris, C F

    1997-03-01

    Anabolic androgenic steroid (AAS) abuse by adolescents represents a significant health care risk due to the potential for long-term negative physical and psychological sequelae, including increased aggressive behavior. The current experiments examined the effects of AAS use in young male adolescent hamsters (Mesocricetus auratus) and their consequences on aggressive behavior. It was hypothesized that AAS administration during adolescence predisposes hamsters to heightened levels of aggressive behavior (i.e., offensive aggression). To test this hypothesis adolescent male hamsters were administered high doses of synthetic AAS to mimic a 'heavy use' self-administration regimen used by athletes. Immediately following the exposure to AAS hamsters were tested for aggressive behavior using a resident-intruder model. Animals treated with high doses of AAS during their adolescent development showed heightened measures of offensive aggression i.e., decreased latency to bite and increased total number of attacks and bites) during the test period, while measures of total activity (total contact time) between the animals remained unchanged. AAS-treated males did not differ in body weight from controls, suggesting that the increased aggression was not due to increased body mass. The results of this study show that exposure to AAS during adolescence facilitates aggressive response patterns, but does not alter body weight.

  19. Pelvic inflammatory disease in the adolescent: a poignant, perplexing, potentially preventable problem for patients and physicians.

    Science.gov (United States)

    Greydanus, Donald E; Dodich, Colleen

    2015-02-01

    The present review considers recent pelvic inflammatory disease literature. It remains a difficult condition to accurately diagnose and manage in the adolescent woman. Failure of accurate diagnosis and prompt management leads to complications, including chronic pelvic pain and infertility. Annual chlamydia screening of sexually active adolescents is an important method for early identification of this common cause of this disorder. Youth with positive screens can be lost for treatment if effective follow-up plans are not in place in clinical practice. The intrauterine device is not a risk factor for this condition in adolescents and is a recommended contraceptive device in sexually active adolescent women. A variety of chlamydial antigens are being used to help differentiate lower genital infection from upper genital disorder. Clinicians are not following established protocols for its diagnosis and management. Sequelae can be reduced in adolescent women if clinicians continue with regular chlamydia screening in sexually active adolescent women, have a low index of suspicion for pelvic inflammatory disease, carefully follow accepted treatment protocols, and teach youth comprehensive sexuality education including regular condom use. Funded research is needed to develop improved diagnosis and management tools as well as a chlamydia vaccine.

  20. Traumatismo alveolodentário na dentição decídua: associação do grau de maturidade radicular no momento de injuria e sequelas após acompanhamento longitudinal retrospectivo.

    OpenAIRE

    2012-01-01

    Este estudo teve como objetivo investigar a influência do grau de maturidade radicular dos dentes decíduos nas sequelas dos traumatismos alveolodentários, assim como investigar o momento que tais sequelas ocorrem. Para tal, foram conduzidos dois estudos longitudinais retrospectivos, os quais coletaram dados clínicos e radiográficos de registros de pacientes com traumatismo dentário em um ou mais incisivo central superior decíduo. No primeiro, sequelas como discoloração coronária, obliteração ...

  1. Child physical abuse and neglect in Kenya, Zambia and the Netherlands: a cross-cultural comparison of prevalence, psychopathological sequelae and mediation by PTSS.

    Science.gov (United States)

    Mbagaya, Catherine; Oburu, Paul; Bakermans-Kranenburg, Marian J

    2013-01-01

    This study compared the prevalence of self-reported childhood physical abuse and neglect and the associated psychopathological sequelae among Kenyan, Zambian, and Dutch university students. In addition, we sought to find out the differentiated role of posttraumatic stress symptoms (PTSS) in mediating the associations between childhood maltreatment experiences and psychopathology symptoms. The sample consisted of 862 university students from Kenya (n = 375), Zambia (n = 182), and The Netherlands (n = 305) who completed the Personal and Relationships Profile (PRP). Results showed that physical abuse was highly prevalent in Kenya (59%) and Zambia (40%), and that neglect was even more prevalent than physical abuse in Zambia and The Netherlands at 59%, 54%, and 42% for the Kenyan, Zambian, and Dutch samples respectively. Neglect was associated with psychopathological symptoms in all three samples, whereas physical abuse was associated with psychopathological sequelae in the Kenyan and Zambian samples only. PTSS mediated the association between neglect and psychopathology symptoms in the Dutch sample and between physical abuse and psychopathology symptoms in the Dutch and Kenyan samples. We conclude that physical abuse and neglect are associated with psychopathology symptoms independently of country and cultural context. However, the pathways through which physical abuse and neglect may lead to psychopathological sequelae may be dependent on perceptions of specific parental behavior in different sociocultural contexts.

  2. Mechanisms linking violence exposure and school engagement among african american adolescents: examining the roles of psychological problem behaviors and gender.

    Science.gov (United States)

    Voisin, Dexter R; Neilands, Torsten B; Hunnicutt, Shannon

    2011-01-01

    This study examines whether the relationship between violence exposure and school engagement is mediated by psychological problem behaviors and whether such relationships are gendered. Five hundred and sixty-three high school African American adolescents (ages 13-19 years) completed questionnaires that assessed two types of violence exposure (community violence and marital conflict), psychological problem behaviors (e.g., posttraumatic stress disorder symptoms, anxiety, withdrawal, and aggressive behaviors), and school engagement (i.e., student-teacher connectedness and grade point average [GPA] obtained from school records). For male adolescents, psychological problem behaviors collectively mediated the relationship between community violence exposure and student-teacher connectedness. For female adolescents, both community violence and marital conflict exposure were negatively related to both GPA and student-teacher connectedness via aggressive behavior. Findings suggest that the differential impact of type of violence exposure and its sequela based on gender should be considered when addressing low school engagement among African American youth.

  3. Adolescent concussions.

    Science.gov (United States)

    Lee, Michael A; Fine, Benjamin

    2010-03-01

    The amount of literature dealing with the diagnosis and treatment of adolescent concussions is considerable. Most articles focus on the athlete. This study examines both sports-related and nonsports-related concussions in adolescents, their etiology, mechanisms of injury (categorized by sport), symptoms exhibited, physical findings, computerized tomography scan results and the problem of prolonged recovery (persistent postconcussion syndrome used in this article to mean symptoms lasting over four weeks.) The purpose of this study is to present the data, their significance and a new method of management that has successfully allowed the author's concussed patients to recover more rapidly. A retrospective review of 863 adolescent concussions, in 11-year-old to 19-year-old patients, from July 2004 through December 31, 2008. Subjects were seen as a result of referrals largely from the author's practice (Pediatric Healthcare Associates), other physicians, athletic trainers or patients previously treated. All concussions, including nonsports-related concussions, were included in the study. Some patients had multiple concussions; 774 individuals accounted for the 863 concussions. The number of patients by age and the number of concussions they sustained are listed below.

  4. Adolescent contraception.

    Science.gov (United States)

    Nelson, A L

    1996-12-01

    By age 19, the average North American man has had sex with 5.11 people. Almost two thirds of high-school senior-aged women have had sex. While the rates of sexual activity among teens in the US are not substantially different from rates in other developed western countries, adolescent pregnancy rates in the US are several times higher than in most other countries. These high rates of adolescent pregnancy are partly due to the collective reluctance among adults in the US to discuss sexuality issues with adolescents and provide them with contraception. Effective communication is the key to providing contraception to teens. Studies have clearly shown that teens are interested in sexuality and would like to discuss the issue with their physicians. The author notes that any successful program to reduce unwanted pregnancies among teens will understand that teens are often concrete thinkers focused upon their physical appearance and dedicated to taking risks. Oral contraception, long-acting progestin methods, condoms, and other options are discussed. However, emergency contraception with birth control pills is the one most important contraceptive option which can be provided to teens. The approach has recently been approved by the FDA Advisory Board for both safety and efficacy. Recent studies, however, show that less than 10% of US clinicians informed their patients of the availability of emergency contraception. Information on providers of emergency contraception can be obtained by dialing Princeton University's Office of Population Research's toll-free emergency contraception hotline at (800) 584-9911.

  5. Delayed neuropsychological sequelae after carbon monoxide poisoning: predictive risk factors in the Emergency Department. A retrospective study

    Directory of Open Access Journals (Sweden)

    Botti Primo

    2011-03-01

    Full Text Available Abstract Background Delayed neuropsychological sequelae (DNS commonly occur after recovery from acute carbon monoxide (CO poisoning. The preventive role and the indications for hyperbaric oxygen therapy in the acute setting are still controversial. Early identification of patients at risk in the Emergency Department might permit an improvement in quality of care. We conducted a retrospective study to identify predictive risk factors for DNS development in the Emergency Department. Methods We retrospectively considered all CO-poisoned patients admitted to the Emergency Department of Careggi University General Hospital (Florence, Italy from 1992 to 2007. Patients were invited to participate in three follow-up visits at one, six and twelve months from hospital discharge. Clinical and biohumoral data were collected; univariate and multivariate analysis were performed to identify predictive risk factors for DNS. Results Three hundred forty seven patients were admitted to the Emergency Department for acute CO poisoning from 1992 to 2007; 141/347 patients participated in the follow-up visit at one month from hospital discharge. Thirty four/141 patients were diagnosed with DNS (24.1%. Five/34 patients previously diagnosed as having DNS presented to the follow-up visit at six months, reporting a complete recovery. The following variables (collected before or upon Emergency Department admission were associated to DNS development at one month from hospital discharge in the univariate analysis: CO exposure duration >6 hours, a Glasgow Coma Scale (GCS score Conclusions Our study identified several potential predictive risk factors for DNS. Treatment algorithms based on an appropriate risk-stratification of patients in the Emergency Department might reduce DNS incidence; however, more studies are needed. Adequate follow-up after hospital discharge, aimed at correct recognition of DNS, is also important.

  6. Neurological Sequelae of Lupus

    Science.gov (United States)

    ... Craniosynostosis Information Page Creutzfeldt-Jakob Disease Information Page Cushing's Syndrome Information Page Dandy-Walker Syndrome Information Page Deep Brain Stimulation for Parkinson's Disease Information Page Dementia Information ...

  7. Pneumococcal Meningitis in an Adolescent with Fever and Foot Ache

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    Catarina Dias

    2013-01-01

    Full Text Available Invasive pneumococcal disease predominantly affects younger children, elderly, and immunocompromised patients. Pneumococcal meningitis is a particularly important form of presentation, considering its high rate of morbimortality. We present the case of a previously healthy 12-year-old adolescent male who was hospitalized due to suspicion of osteoarticular infection in his left foot. A few hours later, he developed meningeal signs, exhibiting slight pleocytosis and Streptococcus pneumoniae isolates in both cerebrospinal fluid and blood. Imaging studies were inconclusive regarding the nature of the foot disorder. We considered the hypothesis of osteomyelitis of the navicular bone as the most likely, for which he completed six weeks of antibiotic therapy. There was a favorable clinical evolution, along with complete absence of osteoarticular or neurological sequelae. The relevance of this clinical case resides in the unusual presentation of invasive pneumococcal disease in this age group, as well as in the rare form of orthopedic involvement.

  8. Pharmacological treatment of bipolar disorder among children and adolescents.

    Science.gov (United States)

    Blader, Joseph C; Kafantaris, Vivian

    2007-03-01

    There is growing recognition that bipolar disorder frequently first presents in adolescence. Preadolescents with volatile behavior and severe mood swings also comprise a large group of patients whose difficulties may lie within the bipolar spectrum. However, the preponderance of scientific effort and clinical trials for this condition has focused on adults. This review summarizes the complexity of bipolar disorder and diagnosis of the disease among young people. It proceeds to review the principles of pharmacotherapy, assess current treatment options and to highlight areas where evidence-based guidance is lacking. Recent developments have enlarged the range of potential treatments for bipolar disorder. Nonetheless, differences in the phenomenology, course and sequelae of bipolar disorder among young people compel greater attention to the benefits and liabilities of therapy for those affected by this illness' early onset. By summarizing current research and opinion on diagnostic issues and treatment approaches, this review aims to provide an update on a clinically important yet controversial topic.

  9. Propylene Glycol Toxicity in Adolescent with Refractory Myoclonic Status Epilepticus

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    Kara A. Bjur

    2017-01-01

    Full Text Available Propylene glycol (PG is a solvent commonly used in medications that, while benign at low doses, may cause toxicity in adults and children at high doses. We describe a case and the physiologic sequelae of propylene glycol toxicity manifested in a critically ill adolescent male with refractory myoclonic status epilepticus aggressively treated with multiple PG-containing medications (lorazepam, phenobarbital, and pentobarbital—all within accepted dosing guidelines and a total daily PG exposure previously recognized to be safe. Hemodynamic measurements by bedside echocardiography during clinical toxicity are also reported. Clinicians should have a high index of suspicion for propylene glycol toxicity in patients treated with PG-containing medications even when the total PG exposure is lower than currently accepted limits.

  10. Health Care Issues for Children and Adolescents in Foster Care and Kinship Care.

    Science.gov (United States)

    2015-10-01

    Children and adolescents who enter foster care often do so with complicated and serious medical, mental health, developmental, oral health, and psychosocial problems rooted in their history of childhood trauma. Ideally, health care for this population is provided in a pediatric medical home by physicians who are familiar with the sequelae of childhood trauma and adversity. As youth with special health care needs, children and adolescents in foster care require more frequent monitoring of their health status, and pediatricians have a critical role in ensuring the well-being of children in out-of-home care through the provision of high-quality pediatric health services, health care coordination, and advocacy on their behalves. Copyright © 2015 by the American Academy of Pediatrics.

  11. Neighborhood Disadvantage and Adolescent Substance Use Disorder: The Moderating Role of Maltreatment.

    Science.gov (United States)

    Handley, Elizabeth D; Rogosch, Fred A; Guild, Danielle J; Cicchetti, Dante

    2015-08-01

    The ecological-transactional model proposes that nested contexts interact to influence development. From this perspective, child maltreatment represents an individual-level risk factor posited to interact with numerous other nested contextual levels, such as the neighborhood environment, to affect development. The aim of this study was to investigate whether adolescents with maltreatment histories represent a vulnerable group for whom disadvantaged neighborhoods confer risk for substance use disorders. Participants were 411 adolescents (age 15-18; mean age = 16.24) from an investigation of the developmental sequelae of childhood maltreatment. Multiple-group structural equation models, controlling for family-level socioeconomic status, indicated that neighborhood disadvantage was associated with more marijuana-dependence symptoms among maltreated but not among non-maltreated adolescents. Moreover, among maltreated adolescents, those who experienced multiple subtypes of maltreatment were at greatest risk for problematic marijuana use in the context of neighborhood disadvantage. Interestingly, the direct effect of neighborhood disadvantage, but not the interaction with maltreatment, was related to adolescent alcohol-dependence symptoms. Results highlight the importance of considering multiple levels of influence when examining risk associated with child maltreatment.

  12. Neurodevelopment: The Impact of Nutrition and Inflammation During Adolescence in Low-Resource Settings.

    Science.gov (United States)

    Galler, Janina R; Koethe, John R; Yolken, Robert H

    2017-04-01

    Approximately 1 out of 5 children worldwide suffers from childhood malnutrition or stunting and associated health conditions, including an increased susceptibility to infections and inflammation. Due to improved early interventions, most children even in low-resource settings now survive early childhood malnutrition, yet exhibit continuing evidence of neurodevelopmental deficits, including poor school achievement and behavioral problems. These conditions are compounded in children who continue to be undernourished throughout the adolescent years. At present, these sequelae of malnutrition and infection are of major concern in the adolescent population, given that young people between the ages of 10 and 24 years represent nearly one-quarter of the world's population. Therefore, there is an urgent need to focus on the well-being of this age group and, in particular, on behavioral, cognitive, and brain disorders of adolescents who experienced malnutrition, infection, and inflammation prenatally, in early childhood, and during adolescence itself. Because one-third of all women globally become pregnant during their adolescent years, brain and behavioral disorders during this period can have an intergenerational impact, affecting the health and well-being of the next generation. This article summarizes the current state of knowledge and evidence gaps regarding childhood and adolescent malnutrition and inflammation and their impact on adolescent neurodevelopment, the limited evidence regarding nutrition and psychosocial interventions, and the role of resilience and protective factors in this age group. This overview should help to inform the development of new strategies to improve the neurodevelopmental outcomes of high risk adolescent populations. Copyright © 2017 by the American Academy of Pediatrics.

  13. Estimativa de sequelas físicas em vítimas de acidentes de transporte terrestre internadas em hospitais do Sistema Único de Saúde

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    Silvânia Suely Caribé de Araújo Andrade

    2016-03-01

    Full Text Available Resumo: Objetivos: Descrever o perfil das vítimas que foram internadas por lesões decorrentes de acidentes de transporte terrestre (ATT e com diagnóstico sugestivo de sequelas físicas, no Brasil, de 2000 a 2013, e analisar sua tendência temporal neste período. Métodos: Estudo ecológico com dados do Sistema de Informações Hospitalares do Sistema Único de Saúde (SIH/SUS. Foi utilizada regressão de Prais-Winstein para estudo das tendências. Resultados: No período estudado, ocorreram 1.747.191 internações por ATT. O estudo destas identificou 410.448 pessoas (23,5% com diagnóstico sugestivo de sequelas físicas. Destas, 77,7% eram do sexo masculino, 26,5% na faixa etária de 20 a 29 anos, 46,4% residentes na Região Sudeste, 32,5% pedestres e 31,1% motociclistas. Para sequela "certeza" foram observadas 51.189 casos (12,5%, 43,8% eram pedestres. Houve 359.259 internações cujo diagnóstico sugeria sequela física "provável", destes 43,3% eram motociclistas. A tendência foi de estabilidade para as internações por ATT relacionadas ao total de pacientes com sequelas físicas e com sequela "provável". Todavia, foi observado aumento nas internações por ATT com diagnóstico sugestivo de sequela "certeza" no sexo masculino e nas regiões Norte e Centro-Oeste. Conclusão: As internações com diagnóstico sugestivo de sequelas físicas representaram cerca de 1/4 das internações por ATT registradas. As maiores proporções foram no sexo masculino, entre os adultos jovens, residentes na região Sudeste e entre os pedestres. Houve estabilidade na tendência das taxas de internação por ATT com diagnóstico sugestivo de sequelas físicas para o Brasil e regiões, mas tendência ascendente para sequela "certeza" para a região Centro-Oeste e Norte e para o sexo masculino.

  14. Comparative Evaluation of Immediate Post-Operative Sequelae after Surgical Removal of Impacted Mandibular Third Molar with or without Tube Drain - Split-Mouth Study

    Science.gov (United States)

    Bhate, Kalyani; Dolas, RS; Kumar, SN Santhosh; Waknis, Pushkar

    2016-01-01

    Introduction Third molar surgery is one of the most common surgical procedures performed in general dentistry. Post-operative variables such as pain, swelling and trismus are major concerns after impacted mandibular third molar surgery. Use of passive tube drain is supposed to help reduce these immediate post-operative sequelae. The current study was designed to compare the effect of tube drain on immediate post-operative sequelae following impacted mandibular third molar surgery. Aim To compare the post-operative sequelae after surgical removal of impacted mandibular third molar surgery with or without tube drain. Materials and Methods Thirty patients with bilateral impacted mandibular third molars were divided into two groups: Test (with tube drain) and control (without tube drain) group. In the test group, a tube drain was inserted through the releasing incision, and kept in place for three days. The control group was left without a tube drain. The post-operative variables like, pain, swelling, and trismus were calculated after 24 hours, 72 hours, 7 days, and 15 days in both the groups and analyzed statistically using chi-square and t-test analysis. Results The test group showed lesser swelling as compared to control group, with the swelling variable showing statistically significant difference at post-operative day 3 and 7 (p≤ 0.05) in both groups. There were no statistically significant differences in pain and trismus variables in both the groups. Conclusion The use of tube drain helps to control swelling following impacted mandibular third molar surgery. However, it does not have much effect on pain or trismus. PMID:28209003

  15. Objective quantification of pulmonary effects in X-ray chest images; Quantificacao objetiva das sequelas pulmonares em imagens de raios-X de torax

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Marcela de; Giacomini, Guilherme; Alvarez, Matheus; Pereira, Paulo M.C.; Ribeiro, Sergio M.; Pina, Diana R. de [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Botucatu, SP (Brazil)

    2016-07-01

    Tuberculosis (TB) is an infectious lung disease of great concern worldwide. Even after treatment, TB leaves pulmonary sequelae that compromise the quality of life of patients. The exam of diagnostic imaging done more frequently is the X-ray chest. The evaluation of pulmonary involvement of these patients is performed visually by the radiologist. The detection and quantification aided by computer systems are of great importance for the more accurate assessment of pulmonary involvement. The objective of this study was to evaluate computationally the reduction of lung damage in X-ray of chest in patients treated with two different medication regimens. (author)

  16. Adolescent and School Health

    Science.gov (United States)

    ... Search Form Controls Cancel Submit Search the CDC Adolescent and School Health Note: Javascript is disabled or ... help strengthen their capacity to improve child and adolescent health. More > DASH Home About DASH At A ...

  17. Treating Children and Adolescents

    Science.gov (United States)

    ... Children and Adolescents Go Back Treating Children and Adolescents Email Print + Share For the most part, the ... side effects. Side effects from sulfasalazine may include headache, sun sensitivity rash, or other signs of sulfa ...

  18. Adolescent health psychology.

    Science.gov (United States)

    Williams, Paula G; Holmbeck, Grayson N; Greenley, Rachel Neff

    2002-06-01

    In this article, a biopsychosocial model of adolescent development is used as an organizing framework for a review of primary, secondary, and tertiary prevention research with adolescent populations. During adolescence many critical health behaviors emerge, affecting future disease outcomes in adulthood. In addition, most of the predominant causes of morbidity and mortality in adolescence are unique to this period of development, indicating that health-focused interventions must be tailored specifically to adolescents. Moreover, it is during adolescence that lifelong patterns of self-management of and adjustment to chronic health conditions are established. Thus, an increased focus on adolescence in health psychology research is important both to improve the health of adolescents per se and to optimize health trajectories into adulthood.

  19. Encyclopedia of adolescence

    NARCIS (Netherlands)

    Brown, B.B.; Prinstein, M.J.

    2011-01-01

    The period of adolescence involves growth, adaptation, and dramatic reorganization in almost every aspect of social and psychological development. The Encyclopedia of Adolescence offers an exhaustive and comprehensive review of current theory and research findings pertaining to this critical decade

  20. Is there a role for diet in ameliorating the reproductive sequelae associated with chronic low-grade inflammation in polycystic ovary syndrome and obesity?

    Science.gov (United States)

    Riley, Joan K; Jungheim, Emily S

    2016-09-01

    A 2013 ASRM committee opinion titled "Optimizing natural fertility" stated that "there is little evidence that dietary variations such as vegetarian diets, low-fat diets, vitamin-enriched diets, antioxidants, or herbal remedies improve fertility …." However, there are emerging epidemiologic data demonstrating that certain components of the diet may influence reproductive health outcomes. Furthermore, translational work with human specimens and animal models lends biologic plausibility to the epidemiologic data, particularly in the context of female reproductive diseases associated with inflammation, including polycystic ovary syndrome (PCOS) and obesity. How to best apply these data clinically for improved reproductive outcomes remains to be determined. In this review, we outline a role for chronic inflammation in the reproductive sequelae of PCOS and obesity and we summarize epidemiologic and translational work demonstrating a potential role for diet in the regulation of inflammatory processes associated with these disorders. These studies identify areas for future research and potential clinical intervention in women affected by the reproductive sequelae of PCOS and obesity. Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  1. Demystifying the Adolescent Brain

    Science.gov (United States)

    Steinberg, Laurence

    2011-01-01

    Understanding the nature of brain development in adolescence helps explain why adolescents can vacillate so often between mature and immature behavior. Early and middle adolescence, in particular, are times of heightened vulnerability to risky and reckless behavior because the brain's reward center is easily aroused, but the systems that control…

  2. Adolescence and Mythology

    Science.gov (United States)

    Anastasopoulos, Dimitris; Soumaki, Eugenia; Anagnostopoulos, Dimitris

    2010-01-01

    The article begins with a brief exploration of the various aspects of adolescent's psychic qualities as these are described in Greek mythology. It is argued that myths are an integral part of the way that adolescence is perceived and myths play an important role in adolescents' psychic and external world, as well as in their mythological thinking.…

  3. 颅脑损伤及其后遗症中医针刺治疗%Chinese Medicine Acupuncture Treatment of Craniocerebral Injury and its Sequelae

    Institute of Scientific and Technical Information of China (English)

    于淼; 王珂; 费智敏

    2016-01-01

    To investigate the trend and harm of brain injury, summarize the mechanism and treatment method of acupuncture treatment of craniocerebral injury and its active significance.: From January 2013 to March 2016, the data of Chinese medicine acupuncture treatment of craniocerebral injury and its sequelae was searched".The data were first selected, including brain injury, incidence trends, hazards, mechanism of action, the law of the use of acupuncture points, the treatment method of the article. Inclusion criteria: craniocerebral injury and its sequelae of acupuncture treatment. Exclusion criteria: repetitive studies.Totally 57 articles about craniocerebral injury and its sequelae of acupuncture treatment of articles, 11 articles were included.Craniocerebral injury and its sequelae of serious threat to human health, traditional Chinese medicine acupuncture can improve the cerebral cortex significantly improve blood circulation, improve tissue oxygen capacity, promote the repair of damaged brain tissue, promote functional recovery. Acupuncture has a definite effect on the function of treating brain injury recovery, is an important means to wake up the patients with long-term coma after craniocerebral injury. This study is to review the research on the treatment of brain injury and its sequelae.%探讨颅脑损伤的发病趋势和危害性,总结中医针刺治疗颅脑损伤及其后遗症作用机制和治疗方法及积极意义。检索万方数据库2013年1月―2016年3月关于颅脑损伤及其后遗症中医针刺治疗的文章,检索词“颅脑损伤,后遗症,针刺疗法”。对资料进行初审,选取包括颅脑损伤、发病趋势、危害性、作用机制、用穴规律、治疗方法的文章。纳入标准:颅脑损伤及其后遗症中医针刺治疗。排除标准:重复性研究。共收集到57篇关于颅脑损伤及其后遗症中医针刺治疗文章,纳入11篇。颅脑损伤及其后遗症严重威胁人类健康,中

  4. Risks and consequences of childhood and adolescent obesity.

    Science.gov (United States)

    Must, A; Strauss, R S

    1999-03-01

    This report reviews the risks and consequences associated with childhood and adolescent obesity. Although no consensus definition of childhood obesity exists, the various measures encountered in the literature are moderately well correlated. The paper is organized in three parts. The first section reviews childhood obesity sequelae that occur during childhood. These short-term risks, for orthopedic, neurological, pulmonary, gasteroenterological, and endocrine conditions, although largely limited to severely overweight children, are becoming more common as the prevalence of severe overweight rises. The social burden of pediatric obesity, especially during middle childhood and adolescence, may have lasting effects on self-esteem, body image and economic mobility. The second section examines the intermediate consequences, such as the development of cardiovascular risk factors and persistence of obesity into adulthood. These mid-range effects of early obesity presage later adult disease and premature mortality. In the final section, the small body of research on the long-term morbidity and mortality associated with childhood obesity is reviewed. These studies suggest that risk of cardiovascular disease and all-cause mortality is elevated among those who were overweight during childhood. The high prevalence and dramatic secular trend toward increasing childhood obesity suggest that without aggressive approaches to prevention and treatment, the attendant health and social consequences will be both substantial and long-lasting.

  5. Mortality among persons with a history of Kawasaki disease in Japan: can paediatricians safely discontinue follow-up of children with a history of the disease but without cardiac sequelae?

    Science.gov (United States)

    Nakamura, Yosikazu; Aso, Eiko; Yashiro, Mayumi; Uehara, Ritei; Watanabe, Makoto; Tajimi, Morihiro; Oki, Izumi; Ojima, Toshiyuki; Yanagawa, Hiroshi; Kawasaki, Tomisaku

    2005-04-01

    To clarify the question of whether patients with Kawasaki disease suffer a higher mortality rate after the incidence of the disease in comparison with age-matched healthy individuals. Between July 1982 and December 1992, 52 collaborating hospitals collected data on all patients having a new, definite diagnosis of Kawasaki disease. Patients were followed up until 31 December 2001 or their death. The expected number of deaths was calculated from Japanese vital statistics data and compared with the observed number. Of 6576 patients enrolled, 29 (20 males and 9 females) died. The standardized mortality ratio (SMR: the observed number of deaths divided by the expected number of deaths based on the vital statistics in Japan) was 1.15 (95% CI: 0.77-1.66). In spite of the high SMRs during the acute phase, the mortality rate was not high after the acute phase for the entire group of patients. Although the SMR after the acute phase was 0.75 for those without cardiac sequelae, six males (but none of the females) with cardiac sequelae died during this period; and the SMR for the male group with cardiac sequelae was 1.95 (95% CI: 0.71-4.25). The mortality from congenital anomalies of the circulatory system was elevated, but no increase in cancer deaths was observed. Although it was not statistically significant, the mortality rate among males with cardiac sequelae due to Kawasaki disease appeared to be higher than in the general population. On the other hand, the mortality rates for females with the sequelae and both males and females without sequelae were not elevated.

  6. Sequelas neurológicas : elaboração de um manual de orientação para o cuidado em saúde

    OpenAIRE

    Oliveira,Magáli Costa; Lucena, Amália de Fátima; Echer, Isabel Cristina

    2014-01-01

    Objetivo: descrever as etapas da elaboração do manual intitulado Sequelas Neurológicas: orientações para pacientes e familiares. Método: estudo de desenvolvimento que apresenta a metodologia utilizada na construção do manual. As etapas consistiram em: elaboração do projeto, seleção de conteúdos do cuidado aos pacientes com acidente vascular encefálico, elaboração do manual piloto, revisão e qualificação da linguagem, ilustrações, layout, avaliação das sugestões e finalização do manual. Os pes...

  7. Severe craniocerebral trauma with sequelae caused by Flash-Ball® shot, a less-lethal weapon: Report of one case and review of the literature.

    Science.gov (United States)

    Hiquet, Jean; Gromb-Monnoyeur, Sophie

    2016-07-01

    The use of Flash-Ball® as a non-lethal weapon by several special units within the police and police forces started in France in 1995. Little literature is available concerning injuries caused by Flash-Ball® shooting. However, we report the case of a healthy 34-year-old male victim of a Flash-Ball® shooting during a riot following a sports event. This young man presented serious craniocerebral injuries with a left temporal fracture, moderate cerebral oedema, fronto-temporal haemorrhagic contusion along with an extra-dural hematoma and subarachnoid hemorrhage requiring neurological and rehabilitation care for two months leaving important sequelae. Although the risk is obviously lower than with firearms, Flash-Ball® is nonetheless potentially lethal and may cause serious physical injuries, particularly after a shot to the head.

  8. Effect of submucosal or oral administration of prednisolone on postoperative sequelae following surgical extraction of impacted mandibular third molar: A randomized controlled study

    Directory of Open Access Journals (Sweden)

    Adebayo Aremu Ibikunle

    2016-01-01

    Full Text Available Background: The aim of the study was to evaluate the effect of preoperatively administered submucosal and oral prednisolone on postoperative pain, facial swelling, and trismus following third molar surgery. Patients and Methods: This was a randomized controlled trial in which subjects were randomly distributed into three groups. Group A consisted of subjects who received 40 mg oral prednisolone; Group B consisted of subjects who received 40 mg submucosal injection of prednisolone while Group C consisted of subjects who did not receive prednisolone. Each group had 62 subjects. Measurements for facial width/facial swelling, pain, and mouth opening were recorded preoperatively and postoperatively. The postoperative evaluation points were postoperative days 1, 3, and 7. These measurements were compared with the preoperative values both within and among the groups. Results: Most of the subjects were in their third decade of life. A considerable increase in the mean postoperative values for pain, facial width and trismus was observed. Notably, subjects who did not receive prednisolone showed comparatively higher values for the measured parameters throughout the postoperative evaluation period. Subjects who received submucosal injection of prednisolone showed overall lower values compared to those who received oral prednisolone. Conclusion: The results of this study indicate that the administration of prednisolone has a significantly beneficial effect in ameliorating the postoperative sequelae of the third molar surgery. In addition, the effect of submucosally injected prednisolone is comparable to the orally administered prednisolone; indeed it shows superiority to the latter in a number of dimensions. Submucosal injection of prednisolone offers a simple, effective, easy, safe, and minimally invasive option to existing therapeutic methods of reducing these postoperative sequelae.

  9. Effect of submucosal or oral administration of prednisolone on postoperative sequelae following surgical extraction of impacted mandibular third molar: A randomized controlled study

    Science.gov (United States)

    Ibikunle, Adebayo Aremu; Adeyemo, Wasiu Lanre; Ladeinde, Akinola Ladipo

    2016-01-01

    Background: The aim of the study was to evaluate the effect of preoperatively administered submucosal and oral prednisolone on postoperative pain, facial swelling, and trismus following third molar surgery. Patients and Methods: This was a randomized controlled trial in which subjects were randomly distributed into three groups. Group A consisted of subjects who received 40 mg oral prednisolone; Group B consisted of subjects who received 40 mg submucosal injection of prednisolone while Group C consisted of subjects who did not receive prednisolone. Each group had 62 subjects. Measurements for facial width/facial swelling, pain, and mouth opening were recorded preoperatively and postoperatively. The postoperative evaluation points were postoperative days 1, 3, and 7. These measurements were compared with the preoperative values both within and among the groups. Results: Most of the subjects were in their third decade of life. A considerable increase in the mean postoperative values for pain, facial width and trismus was observed. Notably, subjects who did not receive prednisolone showed comparatively higher values for the measured parameters throughout the postoperative evaluation period. Subjects who received submucosal injection of prednisolone showed overall lower values compared to those who received oral prednisolone. Conclusion: The results of this study indicate that the administration of prednisolone has a significantly beneficial effect in ameliorating the postoperative sequelae of the third molar surgery. In addition, the effect of submucosally injected prednisolone is comparable to the orally administered prednisolone; indeed it shows superiority to the latter in a number of dimensions. Submucosal injection of prednisolone offers a simple, effective, easy, safe, and minimally invasive option to existing therapeutic methods of reducing these postoperative sequelae. PMID:27833246

  10. Genetic influences on adolescent sexual behavior: Why genes matter for environmentally oriented researchers.

    Science.gov (United States)

    Harden, K Paige

    2014-03-01

    There are dramatic individual differences among adolescents in how and when they become sexually active adults, and early sexual activity is frequently cited as a cause of concern for scientists, policymakers, and the general public. Understanding the causes and developmental impact of adolescent sexual activity can be furthered by considering genes as a source of individual differences. Quantitative behavioral genetics (i.e., twin and family studies) and candidate gene association studies now provide clear evidence for the genetic underpinnings of individual differences in adolescent sexual behavior and related phenotypes. Genetic influences on sexual behavior may operate through a variety of direct and indirect mechanisms, including pubertal development, testosterone levels, and dopaminergic systems. Genetic differences may be systematically associated with exposure to environments that are commonly treated as causes of sexual behavior (gene-environment correlation). Possible gene-environment correlations pose a serious challenge for interpreting the results of much behavioral research. Multivariate, genetically informed research on adolescent sexual behavior compares twins and family members as a form of quasi experiment: How do twins who differ in their sexual experiences differ in their later development? The small but growing body of genetically informed research has already challenged dominant assumptions regarding the etiology and sequelae of adolescent sexual behavior, with some studies indicating possible positive effects of teenage sexuality. Studies of Gene × Environment interaction may further elucidate the mechanisms by which genes and environments combine to shape the development of sexual behavior and its psychosocial consequences. Overall, the existence of heritable variation in adolescent sexual behavior has profound implications for environmentally oriented theory and research.

  11. Genetic Influences on Adolescent Sexual Behavior: Why Genes Matter for Environmentally-Oriented Researchers

    Science.gov (United States)

    Harden, K. Paige

    2013-01-01

    There are dramatic individual differences among adolescents in how and when they become sexually active adults, and “early” sexual activity is frequently cited as a cause of concern for scientists, policymakers, and the general public. Understanding the causes and developmental impact of adolescent sexual activity can be furthered by considering genes as a source of individual differences. Quantitative behavioral genetics (i.e., twin and family studies) and candidate gene association studies now provide clear evidence for the genetic underpinnings of individual differences in adolescent sexual behavior and related phenotypes. Genetic influences on sexual behavior may operate through a variety of direct and indirect mechanisms, including pubertal development, testosterone levels, and dopaminergic systems. Genetic differences may be systematically associated with exposure to environments that are commonly treated as causes of sexual behavior (gene-environment correlation). Possible gene-environment correlations pose a serious challenge for interpreting the results of much behavioral research. Multivariate, genetically-informed research on adolescent sexual behavior compares twins and family members as a form of “quasi-experiment”: How do twins who differ in their sexual experiences differ in their later development? The small but growing body of genetically-informed research has already challenged dominant assumptions regarding the etiology and sequelae of adolescent sexual behavior, with some studies indicating possible positive effects of teenage sexuality. Studies of gene × environment interaction may further elucidate the mechanisms by which genes and environments combine to shape the development of sexual behavior and its psychosocial consequences. Overall, the existence of heritable variation in adolescent sexual behavior has profound implications for environmentally-oriented theory and research. PMID:23855958

  12. Current perspectives in the USA on the diagnosis and treatment of pelvic inflammatory disease in adolescents.

    Science.gov (United States)

    Risser, William L; Risser, Jan M; Risser, Amanda L

    2017-01-01

    In this review, the epidemiology, diagnosis, and treatment of pelvic inflammatory disease (PID) are discussed from a USA perspective and the difficulties that USA adolescents face in recognizing and seeking care for PID and other sexually transmitted infections (STIs) are emphasized. Females aged 15-24 years have the highest incidence of cervical infection with Chlamydia trachomatis and Neisseria gonorrheae, the principal causes of PID. PID is common in this age group. However, the incidence of PID in the USA is not known, because it is not a reportable disease, and because clinicians vary in the criteria used for the diagnosis. The Centers for Disease Control and Prevention (CDC) recommended the following diagnostic criteria that include lower abdominal or pelvic pain and at least one of the following: adnexal tenderness or cervical motion tenderness or uterine tenderness. Because PID can have serious sequelae, the criteria emphasize sensitivity (few false-negatives) at the expense of specificity (some false-positives). Patients who have PID are usually treated in the outpatient setting, following the CDC's Guidelines for the Treatment of Sexually Transmitted Diseases 2015. They receive one dose of an intramuscular cephalosporin, together with 2 weeks of oral doxy cycline, and sometimes oral metronidazole. Improvement should usually be evident in 3 days. The USA does not offer comprehensive sex education for adolescents in public or private schools. Adolescents are unlikely to recognize the symptoms of PID and seek medical treatment. Confidentiality is important to adolescents, and low cost or free sources of confidential care are uncommon, making it unlikely that an adolescent would seek care even if she suspected an STI. The CDC has concluded that screening programs for chlamydia and gonorrhea infection help prevent PID; however, the lack of appropriate sources of care makes adolescents' participation in screening programs unlikely.

  13. Social cognitive development during adolescence

    National Research Council Canada - National Science Library

    Choudhury, Suparna; Blakemore, Sarah-Jayne; Charman, Tony

    2006-01-01

    Social relationships are particularly important during adolescence. In recent years, histological and MRI studies have shown that the brain is subject to considerable structural development during adolescence...

  14. Adolescent childbearing.

    Science.gov (United States)

    Vernon, M

    1991-05-01

    The concern for the consequences of adolescent pregnancy are discussed. Childbirth among unmarried teenagers results in a higher incidence of low birth weight babies, a higher infant mortality and morbidity rate, a higher percentage of childbirth complications, a decreased likelihood of completing school, a higher risk of unemployment and welfare dependency, limited vocational opportunities, larger families, and vulnerability to psychological problems and distress. In 1988, 66% of all births to teens occurred outside of marriage. Out of wedlock live births to teens 14 years rose from 80.8% in 1970 to 92.5% in 1986, and for teens 15-19 years, 29.5% to 60.8%. 70% have a repeat pregnancy within the 1st year following their 1st childbirth. 50% have a 2nd child within 3 years. Most 2nd pregnancies occur in teenagers who are not using effective contractive methods, and the pregnancy is frequently unplanned and unwanted. The factors affecting the rate of 2nd pregnancy are age, race, marital status, education, and economic status. Teenage mothers tend to come from disadvantaged backgrounds, and childbearing compounds the poverty. Aid to families with dependent children 50% of payments were to teen mothers for the birth of their 1st child. Teen fathers are usually low income providers. The public costs are high. Some teen fathers abandon their children after birth, but many are interested in supporting their child. Specific programs to help prepare fathers are needed. Teenage mothers are stressed by child care arrangements, living arrangements, employment, school, relationships with peers, relationships with parents, housework and errands, health, finances, job counseling, community services, and child care information. Parents play an important role in guiding sexual involvement and early childbearing, and need to understand why teens get pregnant and to keep channels of communication open. Teens are influenced by media, peer pressure, lack of self-esteem, unhappiness

  15. Turkish adolescents' loneliness.

    Science.gov (United States)

    Ayhan, Aynur Bütün; Simşek, Sükran; Aral, Neriman; Baran, Gülen

    2012-04-01

    The goal of this study was to characterize loneliness among adolescents with respect to socioeconomic level, sex, and mothers' and fathers' education. General information about the 400 adolescents and their families were obtained. The UCLA Loneliness Scale was administered. Results of a hierarchical multiple regression showed that mothers' educational level explained a slight but statistically significant amount of variance in adolescents' loneliness scores while sex, socioeconomic level and fathers' educational level did not.

  16. Nutrition in the adolescent.

    Science.gov (United States)

    Wahl, R

    1999-02-01

    This article reviews the nutritional requirements of puberty and the clinical assessment of nutritional status, and discusses the nutritional risks imposed by vegetarian diets, pregnancy, and athletic involvement. Energy (calories) and protein are essential in pubertal development. Adolescent females require approximately 2200 calories/day, whereas male adolescents require 2500-3000 calories/day. Additional intake requirements include fat, calcium, iron, zinc, vitamins, and fiber. The clinical assessment of nutritional status begins with obtaining a good diet history of the patient and this could be offered by the body mass index. Nutritional deficiencies and poor eating habits established during adolescence can have long-term consequences, including delayed sexual maturation, loss of final adult height, osteoporosis, hyperlipidemia, and obesity. As for vegetarian adolescents, nutritional risks include lack of iodine, vitamin B12, vitamin D, and some essential fatty acids. In addition, substances in some grains reduce gut absorption, thus increasing mineral deficiencies. Pregnancy may also be a risk factor for poor nutrition during adolescence. A pregnant adolescent has different nutritional needs because she is still growing. Among adolescent athletes many are turning to nutritional supplements in an attempt to improve athletic performance. A balanced, varied diet provides adequate calories and nutrition to meet the needs of most adolescents. They also have greater water needs than do adult athletes. Details on adolescent health concerns are further discussed in this article.

  17. Adolescence and sexuality

    National Research Council Canada - National Science Library

    Kjellberg, G

    2006-01-01

    Different pathological states occurring during adolescence, such as anorexia, bulimia and suicidal attempts are seen as possible manifestations of psychological defence mechanisms against the anxiety...

  18. Adolescent pregnancy and contraception.

    Science.gov (United States)

    Dalby, Jessica; Hayon, Ronni; Carlson, Jensena

    2014-09-01

    7% of US teen women became pregnant in 2008, totaling 750,000 pregnancies nationwide. For women ages 15 to 19, 82% of pregnancies are unintended. Adolescents have a disproportionate risk of medical complications in pregnancy. Furthermore, adolescent parents and their infants both tend to suffer poor psychosocial outcomes. Preventing unintended and adolescent pregnancies are key public health objectives for Healthy People 2020. Screening for sexual activity and pregnancy risk should be a routine part of all adolescent visits. Proven reductions in unintended pregnancy in teens are attained by providing access to contraception at no cost and promoting the most-effective methods.

  19. Mountain biking injuries in children and adolescents.

    Science.gov (United States)

    Aleman, Kylee B; Meyers, Michael C

    2010-01-01

    Over the last decade, the sport of mountain biking has experienced extensive growth in youth participation. Due to the unpredictable nature of outdoor sport, a lack of rider awareness and increased participation, the number of injuries has unnecessarily increased. Many believe that the actual incidence of trauma in this sport is underestimated and is just the 'tip of the iceberg'. The most common mechanism of injury is usually attributed to downhill riding and forward falling. Although rare, this type of fall can result in serious cranial and thoraco-abdominal trauma. Head and neck trauma continue to be documented, often resulting in concussions and the possibility of permanent neurological sequelae. Upper limb injuries range from minor dermal abrasions, contusions and muscular strains to complex particular fracture dislocations. These are caused by attempting to arrest the face with an outstretched hand, leading to additional direct injury. Common overuse injuries include repeated compression from the handlebars and vibration leading to neurovascular complications in the hands. Along with reports of blunt abdominal trauma and lumbar muscle strains, lower extremity injuries may include various hip/pelvic/groin contusions, patellofemoral inflammation, and various muscle strains. The primary causes of mountain biking injuries in children and adolescents include overuse, excessive fatigue, age, level of experience, and inappropriate or improperly adjusted equipment. Additional factors contributing to trauma among this age group involve musculoskeletal immaturity, collisions and falls, excessive speed, environmental conditions, conditioning and fitness status of the rider, nonconservative behavioural patterns, and inadequate medical care. The limited available data restrict the identification and understanding of specific paediatric mountain biking injuries and injury mechanisms. Education about unnecessary risk of injury, use of protective equipment, suitable bikes

  20. Gender and Adolescent Development

    Science.gov (United States)

    Perry, David G.; Pauletti, Rachel E.

    2011-01-01

    This article summarizes and critiques recent trends in research and theory on the role of gender in adolescent development. First, gender differences in key areas of adolescent functioning are reviewed. Second, research on 3 constructs that are especially relevant to the investigation of within-gender individual differences in gender…

  1. Adolescence and Body Image.

    Science.gov (United States)

    Weinshenker, Naomi

    2002-01-01

    Discusses body image among adolescents, explaining that today's adolescents are more prone to body image distortions and dissatisfaction than ever and examining the historical context; how self-image develops; normative discontent; body image distortions; body dysmorphic disorder (BDD); vulnerability of boys (muscle dysmorphia); who is at risk;…

  2. Adolescent Steroid Use.

    Science.gov (United States)

    Office of Inspector General (DHHS), Washington, DC.

    The study focused on non-medical steroid use by adolescents according to data obtained from the National Institute on Drug Abuse, professional literature, 30 key informants knowledgeable in steroid issues, and 72 current or former steroid users. The findings indicated: (1) over 250,000 adolescents, primarily males, used or have used steroids, and…

  3. Diagnosing ADHD in Adolescence

    Science.gov (United States)

    Sibley, Margaret H.; Pelham, William E., Jr.; Molina, Brooke S. G.; Gnagy, Elizabeth M.; Waschbusch, Daniel A.; Garefino, Allison C.; Kuriyan, Aparajita B.; Babinski, Dara E.; Karch, Kathryn M.

    2012-01-01

    Objective: This study examines adolescent-specific practical problems associated with current practice parameters for diagnosing attention-deficit/hyperactivity disorder (ADHD) to inform recommendations for the diagnosis of ADHD in adolescents. Specifically, issues surrounding the use of self- versus informant ratings, diagnostic threshold, and…

  4. Addictions in adolescence

    NARCIS (Netherlands)

    Kleinjan, M.; Engels, R.C.M.E.

    2011-01-01

    An overview of the prevalence, health consequences, and determinants of adolescents' substance use is provided in this article on adolescence and addictions. Additionally, prevention and treatment efforts and the effectiveness are discussed. The emphasis is on alcohol, smoking, and cannabis use.

  5. Inside the Adolescent Brain

    Science.gov (United States)

    Drury, Stacy S.

    2009-01-01

    Dr. Jay Giedd says that the main alterations in the adolescent brain are the inverted U-shaped developmental trajectories with late childhood/early teen peaks for gray matter volume among others. Giedd adds that the adolescent brain is vulnerable to substances that artificially modulate dopamine levels since its reward system is in a state of flux.

  6. Adolescence Education Newsletter, 2001.

    Science.gov (United States)

    Villanueva, Carmelita L., Ed.; Espada-Carlos, Lichelle Dara, Ed.

    2001-01-01

    This document comprises the two 2001 issues of a UNESCO newsletter addressing topics related to adolescent well-being in the Asia-Pacific region, particularly reproductive and sexual health. Each issue contains news from the region on various initiatives related to adolescent health and education, as well as Web links and publications on the…

  7. Adolescence Education Newsletter, 1999.

    Science.gov (United States)

    Villanueva, Carmelita L., Ed.; Padilla, Teresita M., Ed.

    1999-01-01

    This document comprises the two 1999 issues of a UNESCO newsletter addressing topics related to adolescent well-being in the Asia-Pacific region, particularly reproductive and sexual health. Each issue contains news from the region on various initiatives related to adolescent heath and education, as well as Web links and publications on the…

  8. Adolescence Education Newsletter, 1998.

    Science.gov (United States)

    Villanueva, Carmelita L., Ed.; Padilla, Teresita M., Ed.

    1998-01-01

    This document comprises two issues of a new UNESCO newsletter addressing topics related to adolescent well-being in the Asia-Pacific region, particularly reproductive and sexual health. Both issues contain news from the region on various initiatives related to adolescent health and education, as well as Web links and publications on the subject.…

  9. Adolescence Education Newsletter, 2000.

    Science.gov (United States)

    Villanueva, Carmelita L., Ed.; Padilla, Teresita M., Ed.

    2000-01-01

    This document comprises the two 2000 issues of a UNESCO newsletter addressing topics related to adolescent well-being in the Asia-Pacific region, particularly reproductive and sexual health. Each issue contains news from the region on various initiatives related to adolescent health and education, as well as Web links and publications on the…

  10. Adolescence Education Newsletter, 2002.

    Science.gov (United States)

    Villanueva, Carmelita L., Ed.; Espada-Carlos, Lichelle Dara, Ed.

    2002-01-01

    This document consists of the two 2002 issues of a UNESCO newsletter addressing topics related to adolescent well-being in the Asia-Pacific region, particularly reproductive and sexual health. Each issue includes news from the region on various initiatives related to adolescent health and education, as well as Web links and publications on the…

  11. Gender and Adolescent Development

    Science.gov (United States)

    Perry, David G.; Pauletti, Rachel E.

    2011-01-01

    This article summarizes and critiques recent trends in research and theory on the role of gender in adolescent development. First, gender differences in key areas of adolescent functioning are reviewed. Second, research on 3 constructs that are especially relevant to the investigation of within-gender individual differences in gender…

  12. Adolescent Development Reconsidered.

    Science.gov (United States)

    Gilligan, Carol

    1987-01-01

    Emphasizes necessity of reconsideration of adolescent development, for these reasons: the view of childhood has changed; females have not been systematically studied; theories of cognitive development favor mathematical and scientific thinking over the humanities; and because the psychology of adolescence is anchored in separation and independence…

  13. Adolescent Rebellion and Politics.

    Science.gov (United States)

    Meeus, Wim

    1988-01-01

    Examination of 352 Dutch secondary school students reveals that adolescents with high-level education who endorse adolescent rebellion have a more distinctly left-wing profile--in both their political party preferences and their political views--than those with low-level education, who more often ratified political intolerance. (BJV)

  14. The Adolescent Brain

    Science.gov (United States)

    Casey, B. J.; Getz, Sarah; Galvan, Adriana

    2008-01-01

    Adolescence is a developmental period characterized by suboptimal decisions and actions that give rise to an increased incidence of unintentional injuries and violence, alcohol and drug abuse, unintended pregnancy and sexually transmitted diseases. Traditional neurobiological and cognitive explanations for adolescent behavior have failed to…

  15. Early Adolescent Ego Development.

    Science.gov (United States)

    James, Michael A.

    1980-01-01

    Presented are the theoretical characteristics of social identity in early adolescence (ages 10 to 15). It is suggested that no longer is identity thought to begin with adolescence, but may have its beginnings in the preteen years. The article draws heavily on Eriksonian concepts. (Editor/KC)

  16. Adolescents' Perceptions of Alcohol

    Science.gov (United States)

    Roy, Amit; Ikonen, Risto; Keinonen, Tuula; Kumar, Kuldeep

    2017-01-01

    Purpose: Rising trends in alcohol consumption and early drinking initiation pose serious health risks especially for adolescents. Learner's prior knowledge about alcohol gained from the social surroundings and the media are important sources that can impact the learning outcomes in health education. The purpose of this paper is to map adolescents'…

  17. Adolescent Literacy. Focus On

    Science.gov (United States)

    Molineaux, Rebecca

    2009-01-01

    Evidence suggests that there is a crisis in adolescent literacy. Part of the problem is that students often receive little literacy instruction after elementary school. This "Focus On" examines the literacy instruction that adolescents need to be successful as they move on to more challenging texts in middle and high school. In addition, this…

  18. Management of Gonorrhea in Adolescents and Adults in the United States.

    Science.gov (United States)

    Kidd, Sarah; Workowski, Kimberly A

    2015-12-15

    Gonorrhea is the second most commonly reported notifiable disease in the United States and is associated with serious health sequelae, including pelvic inflammatory disease, infertility, and ectopic pregnancy. Treatment for gonorrhea has been complicated by antimicrobial resistance. Neisseria gonorrhoeae has developed resistance to each of the antimicrobials that were previously recommended as first-line treatment regimens, and current treatment options are severely limited. This article summarizes the key questions and data that were discussed at the Sexually Transmitted Diseases (STD) Treatment Guidelines Expert Consultation meeting in April 2013, and the rationale for the 2015 Centers for Disease Control and Prevention STD treatment guidelines for gonococcal infections in adolescents and adults. Key issues addressed include whether to change the dosage of ceftriaxone and azithromycin used in the recommended dual treatment regimen, whether to continue to list dual treatment with cefixime and azithromycin as an alternative treatment regimen, and management of gonococcal infections in persons with severe cephalosporin allergy or suspected treatment failure.

  19. Ulcus vulvae acutum — A case of genital ulcers in adolescent girl

    Directory of Open Access Journals (Sweden)

    Daniela Visentin

    2016-01-01

    Full Text Available Ulcus vulvae acutum is a rare clinical condition characterized by the presence of multiple acute painful genital ulcers of non-venereal origin associated with systemic symptoms in young women. The aetiopathogenesis of the disease is not fully understood, although recent reports have associated it with the Epstein–Barr virus. Diagnosis is difficult and generally made by exclusion after venereal diseases, and autoimmune, inflammatory, traumatic, and neoplastic causes. We describe a case of adolescent female with an episode of ulcus vulvae acutum associated with infectious mononucleosis. The diagnosis was supported by the clinical symptoms, elevated circulating levels of liver enzymes, positive EBV serology, cervical and inguinal lymphadenomegaly, and hepatosplenomegaly. The patient presented a history of aphthous stomatitis. Negative Pathergy test and the absence of any other related symptoms allowed us to exclude the Behçhet syndrome. Lesions healed with no sequelae or recurrences.

  20. Pelvic inflammatory disease in virginal adolescent females without tubo-ovarian abscess.

    Science.gov (United States)

    Kielly, Maria; Jamieson, Mary Anne

    2014-02-01

    Pelvic inflammatory disease (PID) is an infection of the upper genital tract that is often caused by an ascending sexually transmitted infection. The complications of PID include pyosalpinx and tubo-ovarian abscess, infertility or ectopic pregnancy, and chronic pelvic pain of varying degrees. These sequelae underscore the importance of prompt diagnosis. We present 2 cases of PID in young women who denied any history of sexual activity or sexual abuse. Both cases were brought to the operating room with suspected appendicitis; however, laparoscopic evaluation revealed purulent fluid surrounding the pelvic organs. The literature is scant with respect to PID in the virginal patient. It is important to keep pelvic infection in the differential diagnosis of virginal patients who present with clinical symptoms of an acute abdomen. Copyright © 2014 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

  1. Mitigating micro-and macro-vascular complications of diabetes beginning in adolescence.

    Science.gov (United States)

    Moore, Daniel J; Gregory, Justin M; Kumah-Crystal, Yaa A; Simmons, Jill H

    2009-01-01

    Diabetes is a chronic disorder, which manifests when insulin levels or resistance to insulin action becomes insufficient to control systemic glucose levels. Although the number of available agents to manage diabetes continues to expand rapidly, the maintenance of euglycemia by individuals with diabetes remains a substantial challenge. Unfortunately, many patients with type 1 and type 2 diabetes will ultimately experience diabetes complications. These complications result from the toxic effects of chronic hyperglycemia combined with other metabolic derangements that afflict persons with diabetes. This review will present a comprehensive look at the complications of diabetes, the risk factors for their progression, the mechanistic basis for their development, and the clinical approach to screening for, preventing, and treating these sequelae. In addition, since diabetes is commonly diagnosed in childhood, we will provide a special focus on the care of the adolescent patient.

  2. Adolescent depression: a metasynthesis.

    Science.gov (United States)

    Dundon, Edith Emma

    2006-01-01

    Concerns about the adequate assessment and treatment of adolescent depression have been in the forefront of pediatric mental health literature in the recent past. While quantitative studies have provided valuable information, the voice of the adolescent has been lacking in the development of theory and treatment of this prevalent disorder. Using approach, a metasynthesis of six qualitative studies was conducted. This process revealed six themes that outline the course of adolescents who struggle with depression: (a) beyond the blues, (b) spiraling down and within, (c) breaking points, (d) seeing and being seen, (e) seeking solutions, and (f) taking control. Knowledge of the experience of adolescent depression will aid practitioners in recognition and early intervention for the increasing number of adolescents suffering with depression, as well as guide educational initiatives to provide needed information on the symptoms of depression and available resources for getting help.

  3. Depression in adolescence

    Science.gov (United States)

    Thapar, Anita; Collishaw, Stephan; Pine, Daniel S; Thapar, Ajay K

    2012-01-01

    Unipolar depressive disorder in adolescence is common worldwide but often unrecognised. The incidence, notably in girls, rises sharply after puberty and, by the end of adolescence, the 1 year prevalence rate exceeds 4%. The burden is highest in low-income and middle-income countries. Depression is associated with sub stantial present and future morbidity, and heightens suicide risk. The strongest risk factors for depression in adolescents are a family history of depression and exposure to psychosocial stress. Inherited risks, developmental factors, sex hormones, and psychosocial adversity interact to increase risk through hormonal factors and associated perturbed neural pathways. Although many similarities between depression in adolescence and depression in adulthood exist, in adolescents the use of antidepressants is of concern and opinions about clinical management are divided. Effective treatments are available, but choices are dependent on depression severity and available resources. Prevention strategies targeted at high-risk groups are promising. PMID:22305766

  4. Puberty and adolescent sexuality.

    Science.gov (United States)

    Fortenberry, J Dennis

    2013-07-01

    This article is part of a Special Issue "Puberty and Adolescence". Sexuality emerges as a major developmental element of puberty and the adolescent years that follow. However, connecting the sexuality that emerges with puberty and elements of adult sexuality is difficult because much adolescent sexuality research addresses the transition to partnered sexual behaviors (primarily coitus) and consequences such as unplanned pregnancy and sexually transmitted infections. This review proposes a framework of an expanded understanding of puberty and adolescent sexuality from the perspective of four hallmarks of adult sexuality: sexual desire; sexual arousal; sexual behaviors; and, sexual function. This approach thus addresses important gaps in understanding of the ontogeny of sex and the continuum of sexuality development from adolescence through the adult lifespan. Copyright © 2013 Elsevier Inc. All rights reserved.

  5. Adolescent attachment and psychopathology.

    Science.gov (United States)

    Rosenstein, D S; Horowitz, H A

    1996-04-01

    The relationships among attachment classification, psychopathology, and personality traits were examined in a group of 60 psychiatrically hospitalized adolescents. The concordance of attachment classification was examined in 27 adolescent-mother pairs. Both adolescent and maternal attachment status were overwhelmingly insecure and were highly concordant. Adolescents showing a dismissing attachment organization were more likely to have a conduct or substance abuse disorder, narcissistic or antisocial personality disorder, and self-reported narcissistic, antisocial, and paranoid personality traits. Adolescents showing a preoccupied attachment organization were more likely to have an affective disorder, obsessive-compulsive, histrionic, borderline or schizotypal personality disorder, and self-reported avoidant, anxious, and dysthymic personality traits. The results support a model of development of psychopathology based partially on relational experiences with parents.

  6. Assessing Attachment Representations in Adolescents: Discriminant Validation of the Adult Attachment Projective Picture System.

    Science.gov (United States)

    Gander, Manuela; George, Carol; Pokorny, Dan; Buchheim, Anna

    2017-04-01

    The contribution of attachment to human development and clinical risk is well established for children and adults, yet there is relatively limited knowledge about attachment in adolescence due to the poor availability of construct valid measures. The Adult Attachment Projective Picture System (AAP) is a reliable and valid instrument to assess adult attachment status. This study examines for the first time the discriminant validity of the AAP in adolescents. In our sample of 79 teenagers between 15 and 18 years, 42 % were classified as secure, 34 % as insecure-dismissing, 13 % as insecure-preoccupied and 11 % as unresolved. The results demonstrated discriminant validity for using the AAP in that age group, with no associations between attachment classifications and verbal intelligence, social desirability, story length or sociodemographic variables. These results poise the AAP to be used in clinical intervention and large-scale research investigating normative and atypical developmental correlates and sequelae of attachment, including psychopathology in adolescence.

  7. Lacrimal excretory system sequelae in patients treated for leishmaniasis Alterações como seqüelas no sistema lacrimal de portadores de leishmaniose tratada

    Directory of Open Access Journals (Sweden)

    Erika Hoyama

    2006-06-01

    Full Text Available Leishmaniasis infection may involve destruction of nasal tissues resulting in lacrimal drainage system alteration. PURPOSE: To evaluate the frequency of lacrimal excretory system sequelae in patients treated for leishmaniasis. METHODS: Forty-five leishmaniasis-treated patients (90 nasolacrimal ducts were submitted to lacrimal excretory system evaluation. All were evaluated by Jones I test and when it was abnormal, dacryocystography and nasal endoscopy were performed. This situation occurred in 13 patients (26 nasolacrimal ducts. RESULTS: The majority of evaluated patients had the cutaneous form (64.4% of leishmaniasis, however, 69.23% of the patients with lacrimal excretory system alterations had the mucocutaneous form of infection before treatment. In these, the most common alteration detected was bilateral permeable and dilated nasolacrimal ducts (92.30%. Only 3.84% (1/26 of the evaluated nasolacrimal ducts were obstructed. Nasal endoscopy showed turbinate hypertrophy (53.84%, septum deviation (53.84% and nasal septum perforation (23.07%. CONCLUSION: Permeable and dilated lacrimal excretory system were the most common sequelae related to leishmaniasis infection.A leishmaniose pode destruir os tecidos nasais resultando em alterações da via lacrimal excretora. OBJETIVO: Avaliar a ocorrência de alterações do sistema lacrimal excretor em portadores de leishmaniose na fase de pós-tratamento. MÉTODOS: Foi realizada a avaliação da via lacrimal excretora em 45 portadores de leishmaniose tratada (90 vias lacrimais pelo teste de Jones I. Treze pacientes (26 ductos nasolacrimais tiveram o teste de Jones I alterado, tendo sido submetidos a dacriocistografia e endoscopia nasal. RESULTADOS: A maioria dos indivíduos avaliados apresentava a leishmaniose na forma cutânea (64,4%. Entretanto, 69,23% dos indivíduos com alteração do sistema lacrimal excretor apresentavam a forma mucocutânea antes do tratamento. A alteração mais freq

  8. Reconstrucción de las secuelas de la pared abdominal en pacientes con extrofia de cloaca Reconstruction of abdominal wall sequelae in patients with cloacal extrophy

    Directory of Open Access Journals (Sweden)

    P. Iwanyk

    2009-06-01

    Full Text Available Los defectos abdominales congénitos de la línea media inferior, como la extrofia cloacal, se producen por fallos en el mesodermo entre la región umbilical y la membrana cloacal provocando severos defectos viscerales, musculares y óseos. Los reiterados intentos para la reconstrucción de los tractos intestinal y génitourinario en este tipo de malformaciones, pueden ocasionar secuelas graves en la pared malformada. La complejidad de esta malformación y los numerosos procedimientos a los que deben ser sometidos estos pacientes, requieren de un abordaje interdisciplinario desde el inicio del tratamiento y en cada una de las etapas reconstructivas a fin de evitar, al máximo, las lesiones de los tejidos abdominales para lograr, al final, una pared adecuada. Presentamos 2 casos de reconstrucción de la pared abdominal en sendos pacientes de sexo femenino con secuelas importantes de extrofia cloacal, utilizando tejidos expandidos, colgajos musculares y complementando el tratamiento en una de las pacientes con una malla protésica. En ambos casos, y a pesar de la falta de tejido provocada por la malformación y las secuelas de múltiples cirugías, obtuvimos un buen resultado funcional y estético.Abdominal congenital defects of the middle line have their origin in developmental faults of mesoderm between the umbilical region and the cloacal membrane, originating visceral, muscular and osseous defects in the abdominal wall. Repeated attempts to reconstruct the intestinal and genitourinary tract here and in other malformations, can cause serious sequeals in the previously deformed abdominal wall. We present 2 cases of abdominal wall reconstruction in patients with serious sequelae of cloacal extrophy. Complexity of this malformation calls for an interdisciplinary treatment to avoid the severe damage that may be caused during reconstructive attempts. In spite of lack of tissue because of the malformation and the sequelae of multiple surgeries we

  9. Amelioration of acute sequelae of blast induced mild traumatic brain injury by N-acetyl cysteine: a double-blind, placebo controlled study.

    Directory of Open Access Journals (Sweden)

    Michael E Hoffer

    Full Text Available BACKGROUND: Mild traumatic brain injury (mTBI secondary to blast exposure is the most common battlefield injury in Southwest Asia. There has been little prospective work in the combat setting to test the efficacy of new countermeasures. The goal of this study was to compare the efficacy of N-acetyl cysteine (NAC versus placebo on the symptoms associated with blast exposure mTBI in a combat setting. METHODS: This study was a randomized double blind, placebo-controlled study that was conducted on active duty service members at a forward deployed field hospital in Iraq. All symptomatic U.S. service members who were exposed to significant ordnance blast and who met the criteria for mTBI were offered participation in the study and 81 individuals agreed to participate. Individuals underwent a baseline evaluation and then were randomly assigned to receive either N-acetyl cysteine (NAC or placebo for seven days. Each subject was re-evaluated at 3 and 7 days. Outcome measures were the presence of the following sequelae of mTBI: dizziness, hearing loss, headache, memory loss, sleep disturbances, and neurocognitive dysfunction. The resolution of these symptoms seven days after the blast exposure was the main outcome measure in this study. Logistic regression on the outcome of 'no day 7 symptoms' indicated that NAC treatment was significantly better than placebo (OR = 3.6, p = 0.006. Secondary analysis revealed subjects receiving NAC within 24 hours of blast had an 86% chance of symptom resolution with no reported side effects versus 42% for those seen early who received placebo. CONCLUSION: This study, conducted in an active theatre of war, demonstrates that NAC, a safe pharmaceutical countermeasure, has beneficial effects on the severity and resolution of sequelae of blast induced mTBI. This is the first demonstration of an effective short term countermeasure for mTBI. Further work on long term outcomes and the potential use of NAC in civilian m

  10. Thin-section Computed Tomography Detects Long-term Pulmonary Sequelae 3 Years after Novel Influenza A Virus-associated Pneumonia

    Institute of Scientific and Technical Information of China (English)

    Zhi-Heng Xing; Xin Sun; Long Xu; Qi Wu; Li Li; Xian-Jie Wu; Xu-Guang Shao

    2015-01-01

    Background:The aim of this research was to evaluate long-term pulmonary sequelae on paired inspiration-expiration thin-section computed tomography (CT) scans 3 years after influenza A (H 1N 1) virus-associated pneumonia,and to analyze the affecting factors on pulmonary fibrosis.Methods:Twenty-four patients hospitalized with H 1N 1 virus-associated pneumonia at our hospital between September 2009 and January 2010 were included.The patients underwent thin-section CT 3 years after recovery.Abnormal pulmonary lesion patterns (ground-glass opacity,consolidation,parenchymal bands,air trapping,and reticulation) and evidence of fibrosis (architectural distortion,traction bronchiectasis,or honeycombing) were evaluated on follow-up thin-section CT.Patients were assigned to Group 1 (with CT evidence of fibrosis) and Group 2 (without CT evidence of fibrosis).Demographics,rate of mechanical ventilation therapy,rate of intensive care unit admission,cumulative prednisolone-equivalent dose,laboratory tests results (maximum levels of alanine aminotransferase,aspartate transaminase [AST],lactate dehydrogenase [LDH],and creatine kinase [CK]),and peak radiographic opacification of 24 patients during the course of their illness in the hospital were compared between two groups.Results:Parenchymal abnormality was present in 17 of 24 (70.8%) patients and fibrosis occurred in 10 of 24 (41.7%) patients.Patients in Group 1 (10/24; 41.7%) had a higher rate of mechanical ventilation therapy (Z =-2.340,P =0.019),higher number of doses of cumulative prednisolone-equivalent (Z =-2.579,P =0.010),higher maximum level of laboratory tests results (AST [Z =-2.140,P =0.032],LDH [Z=-3.227,P =0.001],and CK [Z=-3.345,P =0.019]),and higher peak opacification on chest radiographs (Z=-2.743,P =0.006) than patients in group 2 (14/24; 58.3%).Conclusions:H1N1 virus-associated pneumonia frequently is followed by long-term pulmonary sequelae,including fibrotic changes,in lung parenchyma.Patients who need

  11. Clinical aspects and self-reported symptoms of sequelae of Yersinia enterocolitica infections in a population-based study, Germany 2009-2010.

    Science.gov (United States)

    Rosner, Bettina M; Werber, Dirk; Höhle, Michael; Stark, Klaus

    2013-05-23

    Foodborne Yersinia enterocolitica infections continue to be a public health problem in many countries. Consumption of raw or undercooked pork is the main risk factor for yersiniosis in Germany. Small children are most frequently affected by yersiniosis. In older children and young adults, symptoms of disease may resemble those of appendicitis and may lead to hospitalization and potentially unnecessary appendectomies. Y. enterocolitica infections may also cause sequelae such as reactive arthritis (ReA), erythema nodosum (EN), and conjunctivitis. We studied clinical aspects of yersiniosis, antimicrobial use, and self-reported occurrence of appendectomies, reactive arthritis, erythema nodosum and conjunctivitis. To assess post-infectious sequelae participants of a large population-based case-control study on laboratory-confirmed Y. enterocolitica infections conducted in Germany in 2009-2010 were followed for 4 weeks. Diarrhea occurred most frequently in children ≤4 years (95%); abdominal pain in the lower right quadrant was most common in children 5-14 years of age (63%). Twenty-seven per cent of patients were hospitalized, 37% were treated with antimicrobials. In 6% of yersiniosis patients ≥5 years of age, appendectomies were performed. Self-reported symptoms consistent with ReA were reported by 12% of yersiniosis patients compared to 5% in a reference group not exposed to yersiniosis. Symptoms consistent with EN were reported by 3% of yersiniosis patients compared to 0.1% in the reference group. Symptoms of conjunctivitis occurred with the same frequency in yersiniosis patients and the reference group. Acute Y. enterocolitica infections cause considerable burden of illness with symptoms lasting for about 10 days and hospitalizations in more than a quarter of patients. The proportion of yersiniosis patients treated with antimicrobial drugs appears to be relatively high despite guidelines recommending their use only in severe cases. Appendectomies and post

  12. Amelioration of Acute Sequelae of Blast Induced Mild Traumatic Brain Injury by N-Acetyl Cysteine: A Double-Blind, Placebo Controlled Study

    Science.gov (United States)

    Slade, Martin D.; Tsao, Jack W.; Hoffer, Barry

    2013-01-01

    Background Mild traumatic brain injury (mTBI) secondary to blast exposure is the most common battlefield injury in Southwest Asia. There has been little prospective work in the combat setting to test the efficacy of new countermeasures. The goal of this study was to compare the efficacy of N-acetyl cysteine (NAC) versus placebo on the symptoms associated with blast exposure mTBI in a combat setting. Methods This study was a randomized double blind, placebo-controlled study that was conducted on active duty service members at a forward deployed field hospital in Iraq. All symptomatic U.S. service members who were exposed to significant ordnance blast and who met the criteria for mTBI were offered participation in the study and 81 individuals agreed to participate. Individuals underwent a baseline evaluation and then were randomly assigned to receive either N-acetyl cysteine (NAC) or placebo for seven days. Each subject was re-evaluated at 3 and 7 days. Outcome measures were the presence of the following sequelae of mTBI: dizziness, hearing loss, headache, memory loss, sleep disturbances, and neurocognitive dysfunction. The resolution of these symptoms seven days after the blast exposure was the main outcome measure in this study. Logistic regression on the outcome of ‘no day 7 symptoms’ indicated that NAC treatment was significantly better than placebo (OR = 3.6, p = 0.006). Secondary analysis revealed subjects receiving NAC within 24 hours of blast had an 86% chance of symptom resolution with no reported side effects versus 42% for those seen early who received placebo. Conclusion This study, conducted in an active theatre of war, demonstrates that NAC, a safe pharmaceutical countermeasure, has beneficial effects on the severity and resolution of sequelae of blast induced mTBI. This is the first demonstration of an effective short term countermeasure for mTBI. Further work on long term outcomes and the potential use of NAC in civilian mTBI is warranted

  13. Thin-section Computed Tomography Detects Long-term Pulmonary Sequelae 3 Years after Novel Influenza A Virus-associated Pneumonia

    Directory of Open Access Journals (Sweden)

    Zhi-Heng Xing

    2015-01-01

    Full Text Available Background: The aim of this research was to evaluate long-term pulmonary sequelae on paired inspiration-expiration thin-section computed tomography (CT scans 3 years after influenza A (H1N1 virus-associated pneumonia, and to analyze the affecting factors on pulmonary fibrosis. Methods: Twenty-four patients hospitalized with H1N1 virus-associated pneumonia at our hospital between September 2009 and January 2010 were included. The patients underwent thin-section CT 3 years after recovery. Abnormal pulmonary lesion patterns (ground-glass opacity, consolidation, parenchymal bands, air trapping, and reticulation and evidence of fibrosis (architectural distortion, traction bronchiectasis, or honeycombing were evaluated on follow-up thin-section CT. Patients were assigned to Group 1 (with CT evidence of fibrosis and Group 2 (without CT evidence of fibrosis. Demographics, rate of mechanical ventilation therapy, rate of intensive care unit admission, cumulative prednisolone-equivalent dose, laboratory tests results (maximum levels of alanine aminotransferase, aspartate transaminase [AST], lactate dehydrogenase [LDH], and creatine kinase [CK], and peak radiographic opacification of 24 patients during the course of their illness in the hospital were compared between two groups. Results: Parenchymal abnormality was present in 17 of 24 (70.8% patients and fibrosis occurred in 10 of 24 (41.7% patients. Patients in Group 1 (10/24; 41.7% had a higher rate of mechanical ventilation therapy (Z = −2.340, P = 0.019, higher number of doses of cumulative prednisolone-equivalent (Z = −2.579, P = 0.010, higher maximum level of laboratory tests results (AST [Z = −2.140, P = 0.032], LDH [Z = −3.227, P = 0.001], and CK [Z = −3.345, P = 0.019], and higher peak opacification on chest radiographs (Z = −2.743, P = 0.006 than patients in group 2 (14/24; 58.3%. Conclusions: H1N1 virus-associated pneumonia frequently is followed by long-term pulmonary sequelae

  14. Development of depression in survivors of childhood and adolescent cancer: a multi-level life course conceptual framework.

    Science.gov (United States)

    Kaye, Erica C; Brinkman, Tara M; Baker, Justin N

    2017-03-09

    As therapeutic and supportive care interventions become increasingly effective, growing numbers of childhood and adolescent cancer survivors face a myriad of physical and psychological sequelae secondary to their disease and treatment. Mental health issues, in particular, present a significant problem in this unique patient population, with depression affecting a sizable number of childhood and adolescent cancer survivors. Multiple key determinants impact a survivor's risk of developing depression, with variables traversing across biologic, individual, family, community, and global levels, as well as spanning throughout the life course of human development from the preconception and prenatal periods to adulthood. A multi-level life course conceptual model offers a valuable framework to identify and organize the diverse variables that modulate the risk of developing depression in survivors of childhood and adolescent cancer. This review describes the first multi-level life course perspective applied to development of depression in childhood and adolescent cancer survivors. This conceptual framework may be used to guide the investigation of mental health interventions for SCACs to ensure that key determinants of depression occurrence are adequately addressed across various levels and throughout the life trajectory.

  15. Associations between obesity, adverse behavioral patterns and cardiovascular risk factors among adolescent inhabitants of a Greek island.

    Science.gov (United States)

    Garoufi, Anastasia; Grammatikos, Evangelos E; Kollias, Anastasios; Grammatikos, Emmanuel; Stergiou, George S; Soldatou, Alexandra

    2017-04-01

    Excess weight, unhealthy lifestyle habits and their sequelae have become a well-recognized public health problem in most countries. The objective of the study was to examine the relationship of adolescent overweight/obesity with behavioral habits and their association with blood pressure (BP) and lipid profile. Anthropometric parameters, lifestyle, BP and lipid profile of 736 adolescents were evaluated cross-sectionally. The classifications of normal weight, overweight and obese were based on BMI z-scores. About 42.1% of adolescents were overweight/obese, 11.3% were smokers, 33.2% consumed alcohol and 34% reported low activity. Males began smoking earlier, consumed alcohol more often, exercised less and spent more screen time than females. Alcohol consumption was more prevalent among smokers and was associated with higher BP and dyslipidemia. Smokers exercised less intensely and had lower high density lipoprotein-cholesterol (HDL-C) than non-smokers. Obesity was a risk factor for higher BP and dyslipidemia. Longer screen time was associated with higher triglycerides, while intense physical activity with lower systolic BP. Obesity is related to an adverse lipid and BP profile during adolescence. Clustering of hazardous habits was observed, which is known to aggravate the cardiovascular risk.

  16. Child and adolescent abuse and neglect in the city of Curitiba, Brazil.

    Science.gov (United States)

    da Silva Franzin, Lucimara Cheles; Olandovski, Márcia; Vettorazzi, Maria Lúcia Tozetto; Werneck, Renata Iani; Moysés, Samuel Jorge; Kusma, Solena Ziemer; Moysés, Simone Tetu

    2014-10-01

    Identify and analyze cases of child and adolescent abuse and neglect in Curitiba, Brazil. This is an exploratory descriptive study that takes a quantitative approach. Secondary data from the reporting registry of the Network for the Protection of Children and Adolescents at Risk for Violence in Curitiba, Brazil, dating from 2004 to 2009, were analyzed. Variables included the victims' sociodemographic profile, place of notification, type, nature and severity of abuse, information about the author of the aggression or abuse, and physical lesions. The frequency distribution and associations between the variables were analyzed using the Chi-square test at a 5% significance level. The analysis of 19,316 records showed that domestic violence, abuse and neglect directed against children and adolescents were the most frequently recorded situation, with 17,082 cases (88.4%) distributed in the following manner: neglect, with 9742 reports (57.0%); physical violence, with 1341 reports (7.9%); sexual violence, with 796 reports (4.7%); psychological violence, with 574 reports (3.4%); and abandonment, with 190 reports (1.1%). Of the total, 43.9% were considered severe cases. The most affected age group was between 5 and 14 years of age, with balance between genders. In the majority of cases, the mother was registered as the author of the abuse or neglect. Physical sequelae (20.2%) mostly affected the head and upper and lower limbs, with consequent lesions manifesting as bruises, cuts, and fractures. An increase in the visibility of domestic violence and children and adolescents abuse and neglect has been observed in the city during the last few years, suggesting the effectiveness of the reporting strategies proposed by the protection network. It is important to increase social security and public welfare policies to prevent child and adolescent abuse and neglect, focusing on family support.

  17. Olanzapine treatment of adolescent rats causes enduring specific memory impairments and alters cortical development and function.

    Directory of Open Access Journals (Sweden)

    Jean A Milstein

    Full Text Available Antipsychotic drugs are increasingly used in children and adolescents to treat a variety of psychiatric disorders. However, little is known about the long-term effects of early life antipsychotic drug treatment. Most antipsychotic drugs are potent antagonists or partial agonists of dopamine D2 receptors; atypical antipsychotic drugs also antagonize type 2A serotonin receptors. Dopamine and serotonin regulate many neurodevelopmental processes. Thus, early life antipsychotic drug treatment can, potentially, perturb these processes, causing long-term behavioral- and neurobiological impairments. Here, we treated adolescent, male rats with olanzapine on post-natal days 28-49. As adults, they exhibited impaired working memory, but normal spatial memory, as compared to vehicle-treated control rats. They also showed a deficit in extinction of fear conditioning. Measures of motor activity and skill, habituation to an open field, and affect were normal. In the orbital- and medial prefrontal cortices, parietal cortex, nucleus accumbens core and dentate gyrus, adolescent olanzapine treatment altered the developmental dynamics and mature values of dendritic spine density in a region-specific manner. Measures of motor activity and skill, habituation to an open field, and affect were normal. In the orbital- and medial prefrontal cortices, D1 binding was reduced and binding of GABA(A receptors with open Cl(- channels was increased. In medial prefrontal cortex, D2 binding was also increased. The persistence of these changes underscores the importance of improved understanding of the enduring sequelae of pediatric APD treatment as a basis for weighing the benefits and risks of adolescent antipsychotic drug therapy, especially prophylactic treatment in high risk, asymptomatic patients. The long-term changes in neurotransmitter receptor binding and neural circuitry induced by adolescent APD treatment may also cause enduring changes in behavioral- and

  18. The mediating role of stigmatization in the mental health of adolescent victims of sexual violence in Eastern Congo.

    Science.gov (United States)

    Verelst, A; De Schryver, M; De Haene, L; Broekaert, E; Derluyn, I

    2014-07-01

    This study aims to explore the factors that explain the mental sequelae of war-related sexual violence and focuses in particular on the role of stigmatization. Drawing on a large-scale quantitative survey undertaken in the war-affected region of eastern Democratic Republic of the Congo, we analyze how stigmatization mediates the mental health impact of sexual violence on adolescent girls who were victims of rape. Twenty-two secondary schools were randomly selected out of a stratified sample in Bunia, Eastern Congo. In a cross-sectional, population-based survey, 1,305 school-going adolescent girls aged 11-23 completed self-report measures assessing war-related traumatic events, experiences of sexual violence, stigmatization, and mental health symptoms. Of the 1,305 participants, 38.2% (n=499) reported experiences of sexual violence. Victims of sexual violence reported more war-related traumatic events and more stigmatization experiences. Several hierarchical regression analyses examined the mediating impact of stigmatization on the relationship between sexual violence and mental health outcomes, thereby controlling for sociodemographics (age, parental availability, and socioeconomic status) and war-related traumatic exposure. Our findings show that this stigmatization largely explains the mental health impact of sexual violence, in particular, on adolescent girls' reported symptoms of depression (full mediation) and posttraumatic stress (avoidance and total PTSD: full mediation; hyperarousal: partial (40%) mediation). No evidence of mediation by stigmatization was found for symptoms of anxiety and intrusion. Stigmatization plays thus an important role in shaping the mental sequelae of sexual violence, a finding with major consequences for clinical practice.

  19. Adolescent and Parental Contributions to Parent-Adolescent Hostility Across Early Adolescence.

    Science.gov (United States)

    Weymouth, Bridget B; Buehler, Cheryl

    2016-04-01

    Early adolescence is characterized by increases in parent-adolescent hostility, yet little is known about what predicts these changes. Utilizing a fairly large sample (N = 416, 51 % girls, 91 % European American), this study examined the conjoint and unique influences of adolescent social anxiety symptoms and parental intrusiveness on changes in parent-adolescent hostility across early adolescence. Higher mother and father intrusiveness were associated with increased mother- and father-adolescent hostility. An examination of reciprocal effects revealed that mother- and father-adolescent hostility predicted increased mother and father intrusiveness. Significant associations were not substantiated for adolescent social anxiety symptoms. These findings suggest that intrusive parenting has important implications for subsequent parent-adolescent interactions and that similar patterns may characterize some aspects of mother- and father-adolescent relationships.

  20. Teaching adolescents about adolescence: experiences from an interdisciplinary adolescent health course.

    Science.gov (United States)

    Aronowitz, Teri

    2006-01-01

    As abstract reasoning increases in complexity, adolescents may face dissonance between new thoughts and prior beliefs. Students in the health professions may be forced to resolve these dissonances in order to execute their professional responsibilities. In developing an undergraduate interdisciplinary course on adolescent health, the authors anticipated challenges in teaching adolescents about adolescence. Over the course of the semester, the anticipated challenges became reality. The author discusses pertinent developmental theories and their application in facilitating late adolescent identity formation and professional role development.

  1. Atopic dermatitis in adolescence

    Directory of Open Access Journals (Sweden)

    Giampaolo Ricci

    2011-12-01

    Full Text Available Atopic dermatitis (AD is a chronic inflammatory skin disorder that typically occurs during childhood especially in the first year of life, with a variable frequency from 10% to 30%. Recent studies have shown that in Europe among 10-20% of children with AD suffer from this disorder also in adolescence. AD is a chronic inflammatory skin disease with a typical onset in the first years of life and with a 10- 30% prevalence among young children. AD prevalence in adolescence has been estimated around 5-15% in European countries. AD persists from childhood through adolescence in around 40% of cases and some risk factors have been identified: female sex, sensitization to inhalant and food allergens, allergic asthma and/or rhinoconjunctivitis, the practice of certain jobs. During adolescence, AD mainly appears on the face and neck, often associated with overinfection by Malassezia, and on the palms and soles. AD persistence during adolescence is correlated with psychological diseases such as anxiety; moreover, adolescents affected by AD might have problems in the relationship with their peers. Stress and the psychological problems represent a serious burden for adolescents with AD and cause a significant worsening of the patients’ quality of life (QoL. The pharmacological treatment is similar to other age groups. Educational and psychological approaches should be considered in the most severe cases.

  2. Effects of “Danzhi Decoction” on Chronic Pelvic Pain, Hemodynamics, and Proinflammatory Factors in the Murine Model of Sequelae of Pelvic Inflammatory Disease

    Directory of Open Access Journals (Sweden)

    Xiaoling Bu

    2015-01-01

    Full Text Available Objective. To evaluate the effect of Danzhi decoction (DZD on chronic pelvic pain (CPP, hemodynamics, and proinflammatory factors of sequelae of pelvic inflammatory diseases (SPID in murine model. Methods. SPID mice were randomly treated with high-dose DZD, mid-dose DZD, low-dose DZD, aspirin, and vehicle for 3 estrous circles. The Mouse Grimace Scale (MGS was performed to evaluate CPP; blood flows of the upper genital tract, pelvic wall, and mesentery were used to assess hemodynamics in SPID mice; expressions of vascular endothelial growth factor (VEGF, angiopoietin-2 (Ang-2, and osteopontin (OPN were measured by Western blot and immunochemistry. Results. Treatment with dose-dependent DZD significantly decreased the MGS scores, accelerated blood flows of the pelvis, and reduced expressions of VEGF, Ang-2, and OPN in the upper genital tract. Conclusions and Discussions. DZD was effective in relieving CPP and improving hemodynamics of the pelvic blood-stasis microenvironment in SPID mice. There was a relationship between CPP and the pelvic blood-stasis microenvironment. Furthermore, DZD might play a positive role in the anti-inflammatory process.

  3. Culture Negative Listeria monocytogenes Meningitis Resulting in Hydrocephalus and Severe Neurological Sequelae in a Previously Healthy Immunocompetent Man with Penicillin Allergy

    Directory of Open Access Journals (Sweden)

    Shahin Gaini

    2015-01-01

    Full Text Available A previously healthy 74-year-old Caucasian man with penicillin allergy was admitted with evolving headache, confusion, fever, and neck stiffness. Treatment for bacterial meningitis with dexamethasone and monotherapy ceftriaxone was started. The cerebrospinal fluid showed negative microscopy for bacteria, no bacterial growth, and negative polymerase chain reaction for bacterial DNA. The patient developed hydrocephalus on a second CT scan of the brain on the 5th day of admission. An external ventricular catheter was inserted and Listeria monocytogenes grew in the cerebrospinal fluid from the catheter. The patient had severe neurological sequelae. This case report emphasises the importance of covering empirically for Listeria monocytogenes in all patients with penicillin allergy with suspected bacterial meningitis. The case also shows that it is possible to have significant infection and inflammation even with negative microscopy, negative cultures, and negative broad range polymerase chain reaction in cases of Listeria meningitis. Follow-up spinal taps can be necessary to detect the presence of Listeria monocytogenes.

  4. [Retention of contrast media in the history of radiology : Sequelae of the former use of thorotrast and new challenges].

    Science.gov (United States)

    van Kaick, G; Delorme, S

    2016-12-01

    Detection of gadolinium deposits in patients who have repeatedly been administered intravenous gadolinium chelates have given rise to concern regarding the long-term safety of magnetic resonance imaging (MRI) contrast media. Nevertheless, negative long-term clinical effects have not yet been observed. In some publications parallels have been drawn to the sequelae of thorotrast that was formerly used for arterial angiography. In this article the history of thorotrast use is briefly described and in particular why, despite warnings, this substance was used frequently and worldwide. A brief summary of the results of the German Thorotrast Study revealed that high excess rates were only observed for primary malignant liver tumors after a 15-year or longer latency period and to a lesser degree of leukemias, as well as for severe local complications due to paravascular injections, particularly in the neck region. Based on this historical review, we will venture to take stock of the outcome from the "success story" of this contrast agent.

  5. Long-term neuropsychological sequelae in HIV-seronegative cryptococcal meningoencephalitis patients with and without ventriculoperitoneal shunts: a cine MRI study.

    Science.gov (United States)

    Chen, Meng-Hsiang; Lu, Cheng-Hsien; Wang, Hung-Chen; Chen, Hsiu-Ling; Tsai, Nai-Wen; Li, Shau-Hsuan; Hsu, Nai-Wen; Lin, Wei-Ming; Kung, Chia-Te; Lin, Wei-Che

    2015-01-01

    Hydrocephalus in cryptococcal meningoencephalitis is most commonly managed with a ventriculoperitoneal shunt. This study applied cine magnetic resonance imaging (MRI) to evaluate initial disease severity on long-term cerebrospinal fluid (CSF) flow dynamics and associated neuropsychological sequelae in cryptococcal meningoencephalitis patients with and without ventriculoperitoneal shunts. Eighteen human immunodeficiency virus-seronegative cryptococcal meningoencephalitis patients (10 with shunts versus 8 without shunts) were compared with 32 age- and sex-matched healthy volunteers. All subjects underwent complete neurologic examination and neuropsychological testing. Cine MRI was conducted to evaluate CSF flow parameters. Initial CSF laboratory analysis and imaging findings were correlated with present CSF flow parameters and neuropsychological scores. Patients without shunts had higher average flow than controls, suggesting chronic hydrocephalus. Initial Evans ratios and CSF glucose levels were associated with CSF peak velocity and flow. Worsening CSF flow parameters correlated with decreased neuropsychological performance. CSF flow parameter differences between the cryptococcal meningoencephalitis patients both with and without ventriculoperitoneal shunts could be detected by cine MRI and correlated with acute stage disease severity and chronic stage neuropsychological results. Cine MRI is useful for assessing the chronic hydrocephalus that may lead to neuropsychological deficits in cryptococcal meningoencephalitis patients.

  6. Effects of “Danzhi Decoction” on Chronic Pelvic Pain, Hemodynamics, and Proinflammatory Factors in the Murine Model of Sequelae of Pelvic Inflammatory Disease

    Science.gov (United States)

    Bu, Xiaoling; Liu, Yanxia; Lu, Qiudan; Jin, Zhe

    2015-01-01

    Objective. To evaluate the effect of Danzhi decoction (DZD) on chronic pelvic pain (CPP), hemodynamics, and proinflammatory factors of sequelae of pelvic inflammatory diseases (SPID) in murine model. Methods. SPID mice were randomly treated with high-dose DZD, mid-dose DZD, low-dose DZD, aspirin, and vehicle for 3 estrous circles. The Mouse Grimace Scale (MGS) was performed to evaluate CPP; blood flows of the upper genital tract, pelvic wall, and mesentery were used to assess hemodynamics in SPID mice; expressions of vascular endothelial growth factor (VEGF), angiopoietin-2 (Ang-2), and osteopontin (OPN) were measured by Western blot and immunochemistry. Results. Treatment with dose-dependent DZD significantly decreased the MGS scores, accelerated blood flows of the pelvis, and reduced expressions of VEGF, Ang-2, and OPN in the upper genital tract. Conclusions and Discussions. DZD was effective in relieving CPP and improving hemodynamics of the pelvic blood-stasis microenvironment in SPID mice. There was a relationship between CPP and the pelvic blood-stasis microenvironment. Furthermore, DZD might play a positive role in the anti-inflammatory process. PMID:27087818

  7. Effects of "Danzhi Decoction" on Chronic Pelvic Pain, Hemodynamics, and Proinflammatory Factors in the Murine Model of Sequelae of Pelvic Inflammatory Disease.

    Science.gov (United States)

    Bu, Xiaoling; Liu, Yanxia; Lu, Qiudan; Jin, Zhe

    2015-01-01

    Objective. To evaluate the effect of Danzhi decoction (DZD) on chronic pelvic pain (CPP), hemodynamics, and proinflammatory factors of sequelae of pelvic inflammatory diseases (SPID) in murine model. Methods. SPID mice were randomly treated with high-dose DZD, mid-dose DZD, low-dose DZD, aspirin, and vehicle for 3 estrous circles. The Mouse Grimace Scale (MGS) was performed to evaluate CPP; blood flows of the upper genital tract, pelvic wall, and mesentery were used to assess hemodynamics in SPID mice; expressions of vascular endothelial growth factor (VEGF), angiopoietin-2 (Ang-2), and osteopontin (OPN) were measured by Western blot and immunochemistry. Results. Treatment with dose-dependent DZD significantly decreased the MGS scores, accelerated blood flows of the pelvis, and reduced expressions of VEGF, Ang-2, and OPN in the upper genital tract. Conclusions and Discussions. DZD was effective in relieving CPP and improving hemodynamics of the pelvic blood-stasis microenvironment in SPID mice. There was a relationship between CPP and the pelvic blood-stasis microenvironment. Furthermore, DZD might play a positive role in the anti-inflammatory process.

  8. Data on medicinal plants used in Central America to manage diabetes and its sequelae (skin conditions, cardiovascular disease, kidney disease, urinary problems and vision loss

    Directory of Open Access Journals (Sweden)

    Peter Giovannini

    2016-06-01

    Full Text Available The data described in this article is related to the review article “Medicinal plants used in the traditional management of diabetes and its sequelae in Central America: a review” (Giovannini et al., 2016 [1]. We searched publications on the useful plants of Central America in databases and journals by using selected relevant keywords. We then extracted reported uses of medicinal plants within the disease categories: diabetes mellitus, kidney disease, urinary problems, skin diseases and infections, cardiovascular disease, sexual dysfunction, vision loss, and nerve damage. The following countries were included in our definition of Central America: Belize, Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica and Panama. Data were compiled in a bespoke Access database. Plant names from the published sources were validated against The Plant List (TPL, (The Plant List, 2013 [2] and accepted names and synonyms were extracted. In total, the database includes 607 plant names obtained from the published sources which correspond to 537 plant taxa, 9271 synonyms and 1055 use reports.

  9. Respuesta endocrina a la aplicación de vibraciones de cuerpo completo en humanos

    Directory of Open Access Journals (Sweden)

    S. Benítez

    2015-09-01

    Full Text Available La realización de ejercicio físico provoca un rompimiento de la homeostasis corporal, induciendo cambios metabólicos, neurales y humorales en el organismo de los seres humanos. Las hormonas cumplen múltiples tareas en el adecuado funcionamiento interno. Las vibraciones de cuerpo completo (VCC se han sugerido en los últimos años como un medio alternativo para la realización de ejercicio físico. Según la bibliografía consultada a través de las VCC se encuentran modificaciones hormonales dependientes de las características intrínsecas de cada protocolo de intervención. El objetivo de esta revisión es recopilar la literatura científica más destacada sobre los efectos que se producen en el sistema endocrino (SE de humanos a través del uso de las VCC.

  10. The reinforcing properties of ethanol are quantitatively enhanced in adulthood by peri-adolescent ethanol, but not saccharin, consumption in female alcohol-preferring (P) rats.

    Science.gov (United States)

    Toalston, Jamie E; Deehan, Gerald A; Hauser, Sheketha R; Engleman, Eric A; Bell, Richard L; Murphy, James M; McBride, William J; Rodd, Zachary A

    2015-08-01

    Alcohol drinking during adolescence is associated in adulthood with heavier alcohol drinking and an increased rate of alcohol dependence. Past research in our laboratory has indicated that peri-adolescent ethanol consumption can enhance the acquisition and reduce the rate of extinction of ethanol self-administration in adulthood. Caveats of the past research include reinforcer specificity, increased oral consumption during peri-adolescence, and a lack of quantitative assessment of the reinforcing properties of ethanol. The current experiments were designed to determine the effects of peri-adolescent ethanol or saccharin drinking on acquisition and extinction of oral ethanol self-administration and ethanol seeking, and to quantitatively assess the reinforcing properties of ethanol (progressive ratio). Ethanol or saccharin access by alcohol-preferring (P) rats occurred during postnatal day (PND) 30-60. Animals began operant self-administration of ethanol or saccharin after PND 85. After 10 weeks of daily operant self-administration, rats were tested in a progressive ratio paradigm. Two weeks later, self-administration was extinguished in all rats. Peri-adolescent ethanol consumption specifically enhanced the acquisition of ethanol self-administration, reduced the rate of extinction for ethanol self-administration, and quantitatively increased the reinforcing properties of ethanol during adulthood. Peri-adolescent saccharin consumption was without effect. The data indicate that ethanol consumption during peri-adolescence results in neuroadaptations that may specifically enhance the reinforcing properties of ethanol during adulthood. This increase in the reinforcing properties of ethanol could be a part of biological sequelae that are the basis for the effects of adolescent alcohol consumption on the increase in the rate of alcoholism during adulthood.

  11. Graffiti and adolescent personality.

    Science.gov (United States)

    Peretti, P O; Carter, R; McClinton, B

    1977-01-01

    Graffiti has been studied for many years from many viewpoints. They have been used to explain accounts of people, styles of life, and assumed relationships. The present paper reports an attempt to analyze graffiti as outward manifestations of adolescent personality. Results suggested that different forms of graffiti could be interpreted from five characterizations of early adolescent personality: sexual maturity, self-identity, idealism, iconoclasm, and rebelliousness. Significant differences were found between boys and girls in numbers of inscriptions for each category. Further, the graffiti were analyzed in relation to early adolescent stages of development.

  12. Bipolar disorder in adolescence.

    Science.gov (United States)

    DeFilippis, Melissa; Wagner, Karen Dineen

    2013-08-01

    Bipolar disorder is a serious psychiatric condition that may have onset in childhood. It is important for physicians to recognize the symptoms of bipolar disorder in children and adolescents in order to accurately diagnose this illness early in its course. Evidence regarding the efficacy of various treatments is necessary to guide the management of bipolar disorder in youth. For example, several medications commonly used for adults with bipolar disorder have not shown efficacy for children and adolescents with bipolar disorder. This article reviews the prevalence, diagnosis, course, and treatment of bipolar disorder in children and adolescents and provides physicians with information that will aid in diagnosis and treatment.

  13. Music Therapy with Adolescents

    Directory of Open Access Journals (Sweden)

    Jukko Tervo

    2005-03-01

    Full Text Available The therapeutic community described in this paper was situated at the University of Oulu Central Hospital Department of Psychiatry, Finland, during the years 1979-1989. The ward consisted of eight beds, four for boys and four for girls. The basic emphasis in the treatment was laid on psychoanalytic psychotherapy and music and art therapies suitable for the stage of adolescent development. Adolescent community therapy (psychoanalytic psychotherapy, music therapy, art therapy, special school etc. creates an environment which supports individual growth of the adolescent and youth culture. This, in turn, simultaneously supports psychotherapy.

  14. Adolescent Egocentrism in Early and Late Adolescence.

    Science.gov (United States)

    Enright, Robert D.; And Others

    1979-01-01

    To assess adolescent egocentrism-sociocentrism, an instrument was devised to measure Elkind's constructs (the imaginary audience, the personal fable, and general self-absorption), plus nonsocial focuses and political focuses. Subjects were ten males and ten females each from three age groups: sixth-grade, eighth-grade, and college. (Author/SJL)

  15. [Adolescence and choice of contraceptive].

    Science.gov (United States)

    Theunissen, L

    1986-11-01

    The majority of books, studies, and publications on adolescence are written by adults, whose frequent focus on unbridled adolescent sexuality, adolescents in crisis, or immature adolescents does not seem to correspond to the self-image of adolescents. All authors agree that adolescence is the period between childhood and adulthood beginning at puberty, but opinions differ as to the termination of adolescence and entrance into adulthood. The most significant consensus about adolescence is its tendency to become prolonged. The majority of authors regard adolescence as a preparation for adult life and hence as a natural phase necessary and indispensable to human existence. Ethnographic studies of societies that do not acknowledge adolescence demonstrate, however, that it is not a natural phase. It is also evident that comparatively few roles in modern society require lengthy periods of preparation such as adolescence. It is therefore difficult to regard adolescence as a time of preparation for adult life. From a historic perspective, adolescence emerged with the socioeconomic transformations of industrialization. Mechanization and automation excluded numerous types of workers, especially young workers, from the labor force. Adolescence represents marginalization of young people in response to socioeconomic exigencies rather than a period of preparation for a better adult life. The marginalization is internalized in the consciousness of adults and youth alike and in their hierarchical relations. The marginalization of young people is expressed in the domain of sexuality by the fact that, although physiologically mature, adolescents are not viewed as psychologically mature enough to have children. Adolescents have sexual relations at increasingly young ages, but unlike adults they are not permitted by society the choice of having a child. Contraception, an option for adults, becomes obligatory for sexually active adolescents. The refusal of contraception or failure to

  16. Abortion in adolescence.

    Science.gov (United States)

    Greydanus, D E; Railsback, L D

    1985-09-01

    This article reviews the difficult but complex subject of abortion in adolescents. Methods of abortion are outlined and additional aspects are presented: psychological effects, counseling issues, and legal parameters. It is our conclusion that intense efforts should be aimed at education of youth about sexuality and prevention of pregnancy, utilizing appropriate contraceptive services. When confronted with a youth having an unwanted pregnancy, all legal options need to be carefully explored: delivery, adoption, or abortion. The decision belongs to the youth and important individuals in her environment. Understanding developmental aspects of adolescence will help the clinician deal with the pregnant teenagers. If abortion is selected, a first trimester procedure is best. Finally, physicians are urged to be aware of the specific, ever changing legal dynamics concerning this subject which are present in their states. Abortion is a phenomenon which has become an emotional but undeniably important aspect of adolescent sexuality and adolescent health care, in this country and around the world.

  17. PCP Use among Adolescents.

    Science.gov (United States)

    Young, Thomas J.

    1987-01-01

    This article, aimed at professionals in the field of adolescent psychology, briefly reviews the use of phencyclidine (PCP), its pharmacology, clinical effects, diagnosis, treatment, and prevention. (Author/BN)

  18. Health counseling of adolescents.

    Science.gov (United States)

    Joffe, A; Radius, S M

    1991-05-01

    Health counseling is a fundamental aspect of health care for adolescents and is a natural extension of the concept of anticipatory guidance. It is a dynamic process involving active participation by adolescents. Pediatricians are a valued source of health-relevant information, but must also recognize how their attitudes and beliefs can affect the counseling process. Knowledge of the multitude of changes occurring during adolescence and an understanding of the role of health-risking behaviors in meeting various developmental needs are critical to successful counseling. Particular attention must be focused on ways to help adolescents develop the skills necessary to maintain health-promoting lifestyles and to resist peer pressure to engage in health-risking behaviors.

  19. Counseling Black Adolescent Parents

    Science.gov (United States)

    Gilbert, Gwendolyn C.

    1974-01-01

    Black adolescent parents need counsel from social workers who are able to intervene with a discerning knowledge of concepts, such as neocolonialism, survival, and liberation, that are important to them and to the black community. (Author)

  20. Adolescents and oral contraceptives.

    Science.gov (United States)

    Sanfilippo, J S

    1991-01-01

    Oral contraceptive (OC) options for adolescents are provides. Clarification for those desiring a birth control method is necessary and the benefits of decreased acne and dysmenorrhea with low dose OCs should be stressed along with the importance of compliance. A community effort is suggested to communicate the sexual and contraceptive alternatives, including abstinence and outercourse (sexual stimulation to orgasm without intercourse). Attention is given to concerns associated with teenage sexual activity, prevention of adolescent pregnancy, contraceptive options for the adolescent patient, adolescent attitudes toward birth control OCs, management of the adolescent OC user, manipulation of steroid components of OCs to respond to adolescent concerns, and other hormonal contraceptive options such as minipills or abstinence. The text is supplemented with tables: the % of US women by single years of age for 1971, 1976, 1979, and 1982; comparative pregnancy and abortion rates for the US and 5 other countries; federal cost for teen childbearing; adolescent nonhormonal contraceptive methods (advantages, disadvantages, and retail cost); checklist to identify those at risk for noncompliance with OCs; hormonal side effects of OCs; risks from OCs to adolescents; and benefits of OCs. Concern about adolescent pregnancy dates back to Aristotle. A modern profile shows girls form single-parent families are sexually active at an earlier age, adolescent mothers produce offspring who repeat the cycle, victims of sexual abuse are more likely to be sexually active, and teenagers in foster care are 4 times more likely to be sexually active and 8 times more likely to become pregnant. Prevention involves a multifaceted approach. OCs are the most appropriate contraceptive choice for adolescents. Frequency of intercourse is closely associated with OC use after approximately 15 months of unprotected sexual activity. At risk for noncompliance variables are scales of personality development

  1. Adolescents sexual practices

    OpenAIRE

    Frias, Ana; Chora, Antónia

    2013-01-01

    Introduction: If teens options are experimenting sexualized practices, we should facilitate their knowledge, make them aware of their choices and help them living their sexuality in a safer mode. Objectives: To identify adolescents sexual practices; characterize the attitudes of teenagers against the use of contraception. Methods: quantitative research with exploratory nature. We studied a convenience sample of 301 adolescents of both sexes whitch attend the 9th grade. Sexual practices and a...

  2. Implants in adolescents.

    Science.gov (United States)

    Shah, Rohit A; Mitra, Dipika K; Rodrigues, Silvia V; Pathare, Pragalbha N; Podar, Rajesh S; Vijayakar, Harshad N

    2013-07-01

    Implants have gained tremendous popularity as a treatment modality for replacement of missing teeth in adults. There is extensive research present on the use of implants in adults, but there is a dearth of data available on the same in adolescents. The treatment planning and execution of implant placement in adolescents is still in its infancy. This review article is an attempt to bring together available literature.

  3. Implants in adolescents

    Directory of Open Access Journals (Sweden)

    Rohit A Shah

    2013-01-01

    Full Text Available Implants have gained tremendous popularity as a treatment modality for replacement of missing teeth in adults. There is extensive research present on the use of implants in adults, but there is a dearth of data available on the same in adolescents. The treatment planning and execution of implant placement in adolescents is still in its infancy. This review article is an attempt to bring together available literature.

  4. Sexting among peruvian adolescents

    OpenAIRE

    West, Joshua H.; Lister, Cameron E; Hall, P Cougar; Crookston, Benjamin T; Snow, Paola Rivera; Zvietcovich, Maria Elena; West, Richard P

    2014-01-01

    Background Sexting (sexual messaging via mobile devices) among adolescents may result in increased risky sexual practices, psychological distress and in some cases, suicide. There is very little research on sexting in developing nations, such as Peru. In particular, little is known about gender differences in the correlates of sexting. The purpose of this study was to determine the sexting prevalence and correlates of sexting among adolescent boys and girls in Cusco, Peru. Methods The study s...

  5. Adolescent fertility: worldwide concerns.

    Science.gov (United States)

    Senderowitz, J; Paxman, J M

    1985-04-01

    There is growing concern over the adverse health, social, economic, and demographic effects of adolescent fertility. Morbidity and mortality rates ar significantly higher for teenage mothers and their infants, and early initiation of childbearing generally means truncated education, lower future family income, and larger completed family size. Adolescent fertility rates, which largely reflect marriage patterns, range from 4/1000 in Mauritania; in sub-Saharan Africa, virtually all rates are over 100. In most countries, adolescent fertility rates are declining due to rising age at marriage, increased educational and economic opportunities for young women, changes in social customs, increased use of contraception, and access to abortion. However, even if fertility rates were to decline dramatically among adolescent women in developing countries, their sheer numbers imply that their fertility will have a major impact on world population growth in the years ahead. The number of women in the world ages 15-19 years is expected to increase from 245 million in 1985 to over 320 million in the years 2020; 82% of these women live in developing countries. As a result of more and earlier premarital sexual activity, fostered by the lengthening gap between puberty and marriage, diminished parental and social controls, and increasing peer and media pressure to be sexually active, abortion and out-of-wedlock childbearing are increasing among teenagers in many developed and rapidly urbanizing developing countries. Laws and policies regarding sex education in the schools and access to family planning services by adolescents can either inhibit or support efforts to reduce adolescent fertility. Since contraceptive use is often sporadic and ineffective among adolescents, family planning services are crucial. Such programs should aim to reduce adolescents' dependence on abortion through preventive measures and increase awareness of the benefits of delayed sexual activity. Similarly, sex

  6. Adolescent rampant caries

    OpenAIRE

    Namita; Rita Rai

    2012-01-01

    Adolescent rampant caries is a new and growing challenge in Conservative Dentistry. It has the same etiology and pattern as that of nursing bottle syndrome. Herein, a case is presented in which the main cause of rampant caries is the patient′s habit of keeping cariogenic food in her mouth and going to sleep. Educating this etiology and introduction of preventive strategies not only assists in meeting the special oral needs of the adolescent population, but also helps to establish lifelong hea...

  7. 外治法治疗盆腔炎性疾病后遗症的研究进展%Review of treating sequelae of pelvic inflammatory disease by external therapy

    Institute of Scientific and Technical Information of China (English)

    刘娅; 王永周

    2014-01-01

    Sequela of pelvic inflammatory disease could lead to chronic pelvic pain, infertility, recurrence of pelvic inflammatory disease, and effect women’s health seriously. This disease is difficult to cure, easily to recrudesce with long course. External treatment is one of many methods on treating sequela of pelvic inflammatory disease. In this paper, literature on treating sequela of pelvic inflammatory disease with external treatment were reviewed, the results is that the efficacy of external treatment is confirmed, fewer side effects, and easily to accept. Research progress on treating sequela of pelvic inflammatory disease with external treatment as followed.%盆腔炎性疾病后遗症会导致慢性盆腔痛、不孕、盆腔炎反复发作等,严重影响妇女的身心健康。本病具有病程长、难治愈、顽固易复发等特点。目前临床上治疗本病的方法种类繁多,外治法是其中的一个大类。笔者通过对近年来外治法治疗盆腔炎性疾病后遗症的文献回归,发现外治法对于本病的治疗具有良好疗效,且毒副作用小,患者易于接受。本文就目前外治法治疗盆腔炎性疾病后遗症的研究进展作一综述。

  8. 健康教育在脑梗塞后遗症患者中的应用%Application of Health Education in the Sequelae of Cerebral Infarction Pa-tients

    Institute of Scientific and Technical Information of China (English)

    孙艳辉

    2016-01-01

    We Analysed the Health Education content sequelae of cerebral infarction patients, obtained the importance of health education at the time of application sequelae of cerebral infarction patients. The main content of sequelae of cerebral infarction patient health education, including three aspects.They were health education basics of education, psychological care and self-care precautions. Among them, the independent care considerations included postural care, diet care, nursing complications. These nursing content, not only can improve patients' knowledge and skills sequelae of cerebral infarction care, supervision and nurses, but also improve patient compliance and self-care initiative.%通过分析健康教育在脑梗塞后遗症患者中的应用内容,得出健康教育在脑梗塞后遗症患者中的应用时的重要意义。脑梗塞后遗症患者的健康教育的主要内容,包括健康教育基本知识宣教、心理护理和自主护理注意事项3个方面。其中,自主护理注意事项包括了体位护理、饮食护理、并发症护理。通过这些护理内容,不仅能够提高患者关于脑梗塞后遗症护理的知识和技能,监督护士工作,还能提高患者自我护理的依从性和主动性。

  9. 老年脑卒中后遗症期患者肺炎危险因素的分析%Risk factors for pneumonia in elderly patients with cerebral stroke sequela

    Institute of Scientific and Technical Information of China (English)

    徐洁; 程鎏

    2013-01-01

    Objective To study the risk factors for pneumonia in elderly patients with cerebral stroke sequela .Methods Clinical data about 330 elderly patients with cerebral stroke sequela (171 pneumonia patients and 159 pneumonia-free patients) were retrospectively analyzed .Results Advanced age(OR= 2 .586 ),history of smoking (OR= 2 .353 ),chronic heart failure (OR= 2 .062 ), dysbulia(OR=2.319),nasal feeding (OR = 4 .708 ) ,completely bedridden (OR= 2 .471) and hy-poalbuminemia(OR=2 .388) were the risk factors for pneumonia in patients with cerebral stroke sequela . Hyperglycemia(OR=0 .341) was a protective factor for it .Conclusion The incidence of pneumonia is high in patients with cerebral stoke sequela due to a variate of risk factors .%目的 探讨脑卒中后遗症期患者肺炎的危险因素.方法 回顾性分析330例脑卒中后遗症期患者的临床资料,进行相关因素分析,其中肺炎患者171例和无肺炎患者159例.结果 高龄(OR=2.586)、吸烟史(OR=2.353)、慢性心力衰竭(OR=2.062)、意识障碍(OR=2.319)、鼻饲(OR=4.708)、完全卧床(OR=2.471)及低白蛋白血症(OR=2.388)是脑卒中后遗症期肺炎的危险因素,高脂血症(OR=0.341)是其保护因素.结论 脑卒中后遗症期肺炎发病率高,危险因素多.

  10. Radiological examination of patients with cranial trauma. Sequelae after minor cranial trauma - a challenge to the radiologist; Radiologiske undersoekelser ved hodeskader. Senfoelger etter lettere hodeskader er en radiologisk utfordring

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, J.L. [Bergen Univ. (Norway); Kraakenes, J. [Haukeland Sykehus, Bergen (Norway)

    1996-08-01

    A brief summary if given of the use of computerized tomography and magnetic resonance imaging (MRI) in cases of cranial trauma. The authors advocate more extended use of MRI in this connection, even in less severe cases. The method is much more sensitive than computer tomography, and thus provides a sounder basis for diagnosis and treatment in patients suffering from late sequelae of cranial injuries. 27 refs., 2 figs.

  11. [Life styles in adolescence: sexual behavior of Portuguese adolescents].

    Science.gov (United States)

    Ferreira, Maria Margarida da Silva Reis Dos Santos; Torgal, Maria Constança Leite de Freitas Paúl Reis

    2011-06-01

    Recent studies have shown that adolescents have initiated their sex lives earlier and earlier, without, however, receiving consistent sex education. The objectives of this study were to analyze the sexual behavior of adolescent high school students and identify the habits of sexual health in sexually active adolescent high school students. An exploratory study was conducted with 680 adolescents, whose age ranged between 15 and 19 years. Results showed that most participants had not initiated their sex life; boys are those who most report having had sexual relations; not all the interviewed adolescents used condoms during sex; most adolescents do not practice sexual health surveillance. It is important for sexually active adolescents to receive health care and counseling. Health institutions and their workers must be proactive in trying to approach adolescents.

  12. Adolescent and parent perceptions of media influence on adolescent sexuality.

    Science.gov (United States)

    Werner-Wilson, Ronald Jay; Fitzharris, Jennifer Lynn; Morrissey, Kathleen M

    2004-01-01

    Empirical evidence suggests that television and other media influence adolescents' attitudes and behaviors. Much of the research in this area is based on surveys in which adolescents are asked to rank the relative importance of a fixed set of factors such as parents, peers, and media. We reviewed data from focus groups conducted with adolescents and their parents to examine the extent to which adolescents identify--without prompting--media as a source of influence on sexual behavior. Adolescents seemed indifferent to media influence (e.g., media influence was mentioned in only one adolescent focus group), but their parents expressed significant concern about media influence. Future research should investigate the extent to which influences exist outside of adolescents' consciousness. For now, parents and sexuality educators may need to convince adolescents that concerns about the media are valid before trying to change media-influenced behavior.

  13. Secuelas de la violencia colectiva: hablan las víctimas del estudio ISAVIC Sequelae of collective violen victims' voices in the ISAVIC study

    Directory of Open Access Journals (Sweden)

    Itziar Larizgoitia

    2011-04-01

    estimate the effects of collective violence on health. The assessment included victims' perceptions of these sequelae and their impact on health. Methods: A purposive sample of 36 primary victims was selected through contact networks and mediators. The victims' perceptions were collected through semi-structured in-depth interviews, which were later analyzed according to the study's conceptual framework. Results: The victims' testimony suggests that they were profoundly traumatized by the collective violence experienced, which was often not yet completely overcome and significantly impaired their quality of life. The main functional, physical, emotional and social limitations described by the victims were identified. Conclusions: The qualitative results of this study are coherent with those obtained through the parametric phase of the ISAVIC study and provide a more complete overview of the nature of the sequelae of collective violence and its impact on quality of life. These results should be verified in larger studies and the influence of the social context on the relationship between collective violence and health should be analyzed in greater depth.

  14. 小儿麻痹后遗膝关节屈曲畸形的矫治%Healing treatment on knee sprung malformation of poliomye lis's sequelae

    Institute of Scientific and Technical Information of China (English)

    蒋文鑫; 谢宏

    2000-01-01

    目的:探讨小儿麻痹(简称儿麻)后遗症膝关节屈曲畸形的手术方式选择及术后功能康复训练。方法:根据膝关节屈曲程度分别采用不同手术方式矫正,术后早期进行静力性肌肉等长收缩等康复训练。结果:治疗88例,优良率达96.5%,无血管、神经并发症发生。结论:据儿麻后遗屈曲的不同程度选用不同的术式,结合术后职业康复训练,对改善病人的下肢功能,疗效满意。%Objective:Selation of ops mode for knee-sprung malformation of poliomyelitis sequelae and post operation training treatment of fun ction healing.Methods:According to the knee-sprung degree,we dopted deferent operatin methods Static muscle's equal-length shrinking on the early stage of post-operation and other rehabili tation training.Results:The ratio of choiceness reach 96.5% and diel not happened the vascalar and nerval synd romes.Conclusion :Aording to the knee-sprung degree,Selecting different OPS and integrating professional healing training after opevation,the crura function of patients will be effectively improved and got satis faitorg avrative effects.

  15. Psychosocial predator-based animal model of PTSD produces physiological and behavioral sequelae and a traumatic memory four months following stress onset.

    Science.gov (United States)

    Zoladz, Phillip R; Park, Collin R; Fleshner, Monika; Diamond, David M

    2015-08-01

    We have a well-established animal model of PTSD composed of predator exposure administered in conjunction with social instability that produces PTSD-like behavioral and physiological abnormalities one month after stress initiation. Here, we assessed whether the PTSD-like effects would persist for at least 4months after the initiation of the psychosocial stress regimen. Adult male Sprague-Dawley rats were exposed to either 2 or 3 predator-based fear conditioning sessions. During each session, rats were placed in a chamber for a 3-min period that terminated with a 30-s tone, followed by 1h of immobilization of the rats during cat exposure (Day 1). All rats in the stress groups received a second fear conditioning session 10days later (Day 11). Half of the stress rats received a third fear conditioning session 3weeks later (Day 32). The two cat-exposed groups were also exposed to daily unstable housing conditions for the entire duration of the psychosocial stress regimen. The control group received stable (conventional) housing conditions and an equivalent amount of chamber exposure on Days 1, 11 and 32, without cat exposure. Behavioral testing commenced for all groups on Day 116. The stress groups demonstrated increased anxiety on the elevated plus maze, impaired object recognition memory and robust contextual and cued fear conditioned memory 3months after the last conditioning session. Combined data from the two stress groups revealed lower post-stress corticosterone levels and greater diastolic blood pressure relative to the control group. These findings indicate that predator-based psychosocial stress produces persistent PTSD-like physiological and behavioral abnormalities that may provide insight into the neurobiological and endocrine sequelae in traumatized people with PTSD.

  16. Adolescent-Parent Conflict among Chinese Adolescents in Hong Kong.

    Science.gov (United States)

    Yau, Jenny; Smetana, Judith G.

    1996-01-01

    Interviewed 120 early, mid, and late adolescents of lower-class Chinese families to examine adolescent-parent conflict. Found that conflicts were primarily with mothers, of moderate frequency and severity, and occurred over everyday issues. Adolescents wanted greater autonomy in decision making than their parents granted them, but parents' views…

  17. Motivational Interviewing and Adolescent Psychopharmacology

    Science.gov (United States)

    Dilallo, John J.; Weiss, Gony

    2009-01-01

    The use of motivational interviewing strategies in the practice of adolescent psychopharmacology is described. Motivational interviewing is an efficient and collaborative style of clinical interaction and this helps adolescent patients to integrate their psychiatric difficulties into a more resilient identity.

  18. Psychotherapies for Children and Adolescents

    Science.gov (United States)

    ... Facts for Families Guide Psychotherapy for Children and Adolescents: Different Types No. 86; updated February 2017 Psychotherapy ... Therapy (DBT) can be used to treat older adolescents who have chronic suicidal feelings/thoughts, engage in ...

  19. Scoliosis in Children and Adolescents

    Science.gov (United States)

    ... Questions and Answers about Scoliosis in Children and Adolescents This publication defines scoliosis and provides information about ... it is diagnosed and treated in children and adolescents. You may be interested in contacting one or ...

  20. Gay, Lesbian and Bisexual Adolescents

    Science.gov (United States)

    ... Facts for Families Guide Gay, Lesbian and Bisexual Adolescents No. 63; Updated October 2013 Growing up is a demanding and challenging task for every adolescent. One important aspect is forming one's sexual identity. ...

  1. Study progress of sequelaes and risk factors of bacterial meningitis in children%儿童细菌性脑膜炎的后遗症及其危险因素研究进展

    Institute of Scientific and Technical Information of China (English)

    张金晶; 王亚娟

    2013-01-01

    儿童细菌性脑膜炎仍是导致儿童死亡的重要原因,而细菌性脑膜炎所致后遗症也并不少见,细菌性脑膜炎患者出院后至少发生1种后遗症的平均概率为19.9%,包括听力障碍、认知障碍、运动障碍、癫(癎)、视力障碍等,其中听力障碍是最常见的后遗症,多种后遗症可同时存在.入院时患儿的意识水平、惊厥、起病时间>48 h、外周循环衰竭、致病菌为肺炎链球菌是细菌性脑膜炎发生后遗症的公认危险因素.外周血白细胞计数、脑脊液糖及蛋白水平亦与细菌性脑膜炎预后密切相关.入院时低钠血症提示预后不良.男童及激素的应用对细菌性脑膜炎后遗症影响尚无定论.%Bacterial meningitis in children is still a life-threatening disease which causes a serious of sequelaes,the median risk of at least 1 major or minor sequelae after hospital discharge is 19.9%,including hearing impairment,cognitive impairment,motor disorders,seizures,visual impairment and so on.Of all these sequelaes,hearing impairment is the most common type.Multiple sequelae is recognized.Prognostic factors are found to be statistically significant:coma/impaired consciousness,complaints > 48 hours before admission,seizures at admission,peripheral circulatory failure,respiratory distress,Streptococcus pneumonia as causative pathogen were recognized as the risk factors for sequeales.And cerebrospinal fluid parameters and white blood cell count were closely related to sequelaes.Hypokaliemia at admission also indicate poor prognosis,but need independent validation in clinical works.Male gender and corticoids were still in discussion.

  2. Sequelae of neglected senile cataract

    Directory of Open Access Journals (Sweden)

    Azhany Y

    2013-05-01

    Full Text Available Cataract is the most common cause of blindness in the world. An attack of phacolytic and phacomorphic glaucoma as a result of neglected cataract constitutes a medical emergency that must be addressed immediately. Ocular emergencies such as these is challenging for the surgeon with guarded or poor prognosis. We describe the presentation, management and prognosis of three cases of phacomorphic and phacolytic glaucoma. All three patients underwent aggressive management of intraocular pressure. Despite successful cataract operation with implantation of intraocular lens, there was only mild improvement of the vision. Optic nerve and pupil functions were permanently affected following the insult. Phacomorphic and phacolytic glaucoma present a very challenging problem to the surgeon with poor visual outcome. Public health education and awareness are important and health workers should encourage patients with cataract to seek early treatment for better prognosis.

  3. [Minor sequelae of ambulatory anesthesia].

    Science.gov (United States)

    Melloni, C; Fusari, M; Ortelli, L; Belelli, G; Di Marco, M G; De Eccher, L; Rainaldi, P; Cuconati, N

    1987-12-01

    Voluntary abortions in day hospitals fulfill the need for shorter hospital stays and minimal interference with patient activities; on the other hand, it makes it more difficult to evaluate the possible complications of anesthesia. 1820 patients who received general anesthesia for voluntary abortion were given a questionnaire before they were discharged; items queried included drowsiness, headache, dizziness, nausea or vomiting, sore throat or mouth, abdominal cramps, pain at IV site, backache or muscular cramps, inability to perform daily activities. Only 465 patients returned the questionnaire. The most frequent complaint was sleepiness or drowsiness (19.8%), headache (7.1%), dizziness (15.1%), nausea or vomiting (8.2%), abdominal cramps (24.7%), and backache (16.7%). There seems to be less nausea or vomiting with the use of pentothal rather than alothane. Ketamine was never used on its own. The findings seen to suggest that the simplest combinations of drugs result in fewer and less severe complications than the use of several drugs.

  4. Delayed sequelae of pituitary irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Woodruff, K.H.; Lyman, J.T.; Lawrence, J.H.; Tobias, C.A.; Born, J.L.; Fabrikant, J.I.

    1984-01-01

    Since 1958, 781 patients at Lawrence Berkeley Laboratory have received helium-particle stereotactic radiosurgery to the adenohypophysis. Autopsy findings in 15 of these patients are reported. Ten patients received pituitary radiation (average dose, 116 Gy in six fractions) for progressive neovascularization retinopathy due to diabetes mellitus. Evidence of a time-dependent course of progressive fibrosis in their pituitary glands was found. Five patients were treated for eosinophilic adenomas. Although they had lower average doses of radiation (56 Gy in six fractions), their pituitary glands showed cystic cavitation of the adenomas. The adenomas thus appeared more radiosensitive than the normal pars anterior, which, in turn, was more radiosensitive than the adjacent neurohypophysis. No significant radiation changes were found in the surrounding brain or cranial nerves. The endocrine organs under pituitary control showed varying degrees of atrophy, and clinical tests revealed progressive hypofunction. It was concluded that charged-particle therapy produced a sharply delineated focal ral tests revealed progressive hypofunction. It was concluded that charged-particle therapy produced a sharply delineated focal radiation lesion confined to the pituitary gland but did not cause injury to the critical structures of the surrounding central nervous system.

  5. [Reconstruction of facial burn sequelae].

    Science.gov (United States)

    Foyatier, J L; Comparin, J P; Boulos, J P; Bichet, J C; Jacquin, F

    2001-06-01

    The deep burns of the face can lead to horrible scars functionally and aesthetically. Treatment of these scars need several surgical interventions frequently and during many years. In our region we deal with this type of wounds as team work, multidisciplinary approach carrying out many process starting by emergency treatment of acute burns till the social rehabilitation. The expansion technique was great help in improving the shape of scars, by using the expanding skin as full thickness grafts. Reconstruction of the anatomical units and application of aesthetic techniques (like rhinoplasty, lifting, tattooing and autologous fat injections) participate equally in improving the quality of results. Many examples of treatments of burns scars are shown.

  6. Sequelae and rehabilitation of stroke.

    Science.gov (United States)

    Ueda, S

    1991-10-01

    During rehabilitation after stroke, evaluation and treatment are carried out for sensorimotor impairments such as hemiplegia or dysphagia, perceptual-cognitive impairments such as unilateral spatial neglect, disabilities such as dependence in activities of daily living, as well as various types of handicaps. Research into these problems is reviewed.

  7. Self constructing in adolescence

    Directory of Open Access Journals (Sweden)

    Vranješević Jelena

    2003-01-01

    Full Text Available The aim of this study was to explore “theories” adolescents have about themselves, i.e. about the changes in the ways they construe themselves in the period of middle adolescence: how they construe changes and estimate them according to some dimensions relevant for change (appreciation of change, its importance, expectancy, timing, comprehensiveness, intensity and visibility in social surroundings. The study was explorative and it was performed on the sample of 96 adolescents aged 15-17 (middle adolescence. Instruments used for the study were: interview and Role Construct Repertory Grid, adjusted to the need of study. The results show that the adolescents’ construct system is highly monolithic and tight in regard to constructs (black and white construing, but at the same time vague and predictively unclear in regard to elements, i. e. the stated changes, meaning that adolescents are not able to construe those changes according to certain constructs. It seems that this study included the beginning of the loosening phase (creativity cycle in which the system is still tight and, therefore, protects from threat and anxiety, while the elements are not predictively (this is what Erikson calls moratorium, i.e. the process of active experimenting. Changes which are fully predictively are those which refer to adults' roles, such as: self confident, experienced, independent and has responsibilities, worries. On the hand, changes which are predictably the most clear to adolescents (and not appreciated are depression and nervousness. Adolescents face an implicative dilemma: positive implications of maturity are not enough, while negative implications, such as nervousness, depression and not trusting people are clear, predictable and negative. This dilemma can be the cause of their ambivalence towards growing-up and accepting the roles of adults.

  8. Adolescent Pregnancy and Special Education.

    Science.gov (United States)

    Anastasiow, Nicholas J.

    1983-01-01

    The article discusses the complex set of factors involved in the phenomena associated with adolescent pregnancy and child bearing, particularly the young adolescent's risk in bearing and/or rearing a handicapped child. Programs to reduce adolescent pregnancies, teach about child development, and child care procedures are described. (Author/CL)

  9. Anger Communication in Bicultural Adolescents

    Science.gov (United States)

    Novin, Sheida; Rieffe, Carolien

    2012-01-01

    Little is known about bicultural adolescents' emotional competence. The aim of the present study was to examine anger communication by comparing thirty-eight 16-year-old Moroccan-Dutch adolescents with 40 Dutch and 40 Moroccan peers using hypothetical anger-eliciting vignettes. Findings show that although Moroccan and Dutch adolescents were…

  10. Eating Disorders in Adolescent Males

    Science.gov (United States)

    Ray, Shannon L.

    2004-01-01

    Research indicates that the primary onset of eating disorders occurs in adolescence and that there is a growing prevalence of adolescent males with eating disorders. This article describes the eating disorders of anorexia nervosa and bulimia nervosa as they relate to adolescent males. Diagnostic criteria, at-risk groups, and implications for…

  11. Popular Music in Early Adolescence.

    Science.gov (United States)

    Christenson, Peter G.; Roberts, Donald F.

    This paper examines young adolescents' involvement with popular music and the health implications of that involvement. Initial discussion explores three central concepts: music media, adolescence, and mass media effects. A summary of research on music media in adolescence is offereed in two sections discussing exposure to, and gratifications and…

  12. Rorschach Evaluation of Adolescent Bulimics.

    Science.gov (United States)

    Smith, Jane E.; And Others

    1991-01-01

    Used Rorschach Test to contrast 12 diagnosed female adolescent bulimics with 12 female adolescent controls. Bulimics averaged greater number of aggression responses. Data suggest that adolescent bulimics are more depressed, self-punitive, and negativistic than peers and that they have more disordered thoughts, inaccurate perceptions, and impaired…

  13. Child Maltreatment and Adolescent Development

    Science.gov (United States)

    Trickett, Penelope K.; Negriff, Sonya; Ji, Juye; Peckins, Melissa

    2011-01-01

    Child abuse and neglect, often collectively called child maltreatment, are huge social problems affecting millions of children and adolescents in America. Adolescents are affected both by maltreatment which occurred during childhood with lingering effects and by maltreatment that continues into or begins in adolescence. Several decades of research…

  14. Adolescent male health.

    Science.gov (United States)

    Westwood, Michael; Pinzon, Jorge

    2008-01-01

    Although adolescent males have as many health issues and concerns as adolescent females, they are much less likely to be seen in a clinical setting. This is related to both individual factors and the health care system itself, which is not always encouraging and set up to provide comprehensive male health care. Working with adolescent boys involves gaining the knowledge and skills to address concerns such as puberty and sexuality, substance use, violence, risk-taking behaviours and mental health issues. The ability to engage the young male patient is critical, and the professional must be comfortable in initiating conversation about a wide array of topics with the teen boy, who may be reluctant to discuss his concerns. It is important to take every opportunity with adolescent boys to talk about issues beyond the presenting complain, and let them know about confidential care. The physician can educate teens about the importance of regular checkups, and that they are welcome to contact the physician if they are experiencing any concerns about their health or well-being. Parents of preadolescent and adolescent boys should be educated on the value of regular health maintenance visits for their sons beginning in their early teen years.

  15. Personality disorders in adolescence.

    Directory of Open Access Journals (Sweden)

    Kamila Lenkiewicz

    2015-08-01

    Full Text Available Adult personality disorders are well recognized and described in the literature. The discussion about the possibility of the presence of personality disorders in adolescents started about 20 years ago. Some authors claim the before the age of 18 it is only possible to identify precursors of future personality disorders and such a standpoint is reflected in diagnostic criteria. This is based on the assumption that personality in adolescence is still not well established. Consequently, the criterion on the persistence of symptoms for the period of time cannot be met (the persistence of symptoms of personality disorders for the period of at least two years. Other approach postulates that problems presented in adolescence should not be exclusively limited to Axis I according to DSM. The proponents of this approach claim that current diagnostic tools are not adjusted to adolescents, thus it is very difficult to measure stability and persistence of symptoms in this age group. This paper presents literature review on personality disorders in adolescence.

  16. Adolescents and their music. Insights into the health of adolescents.

    Science.gov (United States)

    Brown, E F; Hendee, W R

    During adolescence, teenagers are expected to develop standards of behavior and reconcile them with their perceptions of adult standards. In this context, music, a powerful medium in the lives of adolescents, offers conflicting values. The explicit sexual and violent lyrics of some forms of music often clash with the themes of abstinence and rational behavior promoted by adult society. Identification with rock music, particularly those styles that are rejected by adults, functions to separate adolescents from adult society. Some forms of rock music extend well beyond respectability in fulfilling this definitional role. Total immersion into a rock subculture, such as heavy metal, may be both a portrait of adolescent alienation and an unflattering reflection of an adolescent's perception of the moral and ethical duplicity of adult society. Physicians should be aware of the role of music in the lives of adolescents and use music preferences as clues to the emotional and mental health of adolescents.

  17. Adolescent Perceptions of Parental Behaviors, Adolescent Self-Esteem, and Adolescent Depressed Mood

    Science.gov (United States)

    Plunkett, Scott W.; Henry, Carolyn S.; Robinson, Linda C.; Behnke, Andrew; Falcon, Pedro C., III

    2007-01-01

    Using symbolic interaction, we developed a research model that proposed adolescent perceptions of parental support and psychological control would be related to adolescent depressed mood directly and indirectly through self-esteem. We tested the model using self-report questionnaire data from 161 adolescents living with both of their biological…

  18. Adolescent Perceptions of Parental Behaviors, Adolescent Self-Esteem, and Adolescent Depressed Mood

    Science.gov (United States)

    Plunkett, Scott W.; Henry, Carolyn S.; Robinson, Linda C.; Behnke, Andrew; Falcon, Pedro C., III

    2007-01-01

    Using symbolic interaction, we developed a research model that proposed adolescent perceptions of parental support and psychological control would be related to adolescent depressed mood directly and indirectly through self-esteem. We tested the model using self-report questionnaire data from 161 adolescents living with both of their biological…

  19. Predictive factors of depression symptoms among adolescents in the 18-month follow-up after Wenchuan earthquake in China.

    Science.gov (United States)

    Chui, Cheryl H K; Ran, Mao-Sheng; Li, Rong-Hui; Fan, Mei; Zhang, Zhen; Li, Yuan-Hao; Ou, Guo Jing; Jiang, Zhe; Tong, Yu-Zhen; Fang, Ding-Zhi

    2017-02-01

    It is unclear about the change and risk factors of depression among adolescent survivors after earthquake. This study aimed to explore the change of depression, and identify the predictive factors of depression among adolescent survivors after the 2008 Wenchuan earthquake in China. The depression among high school students at 6, 12 and 18 months after the Wenchuan earthquake were investigated. The Beck Depression Inventory (BDI) was used in this study to assess the severity of depression. Subjects included 548 student survivors in an affected high school. The rates of depression among the adolescent survivors at 6-, 12- and 18-month after the earthquake were 27.3%, 42.9% and 33.3%, respectively, for males, and 42.9%, 61.9% and 53.4%, respectively, for females. Depression symptoms, trauma-related self-injury, suicidal ideation and PTSD symptoms at the 6-month follow-up were significant predictive factors for depression at the 18-month time interval following the earthquake. This study highlights the need for considering disaster-related psychological sequela and risk factors of depression symptoms in the planning and implementation of mental health services. Long-term mental and psychological supports for victims of natural disasters are imperative.

  20. Adaptive behaviour in children and adolescents with foetal alcohol spectrum disorders: a comparison with specific learning disability and typical development.

    Science.gov (United States)

    Fagerlund, Åse; Åse, Fagerlund; Autti-Rämö, Ilona; Ilona, Autti-Rämö; Kalland, Mirjam; Mirjam, Kalland; Santtila, Pekka; Pekka, Santtila; Hoyme, H Eugene; Eugene, Hoyme H; Mattson, Sarah N; Sarah, Mattson N; Korkman, Marit; Marit, Korkman

    2012-04-01

    Foetal alcohol spectrum disorders (FASD) is a leading cause of intellectual disability in the western world. Children and adolescents with FASD are often exposed to a double burden in life, as their neurological sequelae are accompanied by adverse living surroundings exposing them to further environmental risk. In the present study, the adaptive abilities of a group of children and adolescents with FASD were examined using the Vineland Adaptive Behaviour Scales (VABS) and compared to those of a group of IQ-matched children with specific learning disorder (SLD) as well as with typically developing controls (CON). The results showed significantly different adaptive abilities among the groups: Children with FASD performed worse than IQ-matched children with SLD, who in turn performed worse than typically developing children on all domains (communication, daily living skills and socialization) on the VABS. Compared to the other groups, social skills declined with age in the FASD group. These results support previous studies of adaptive behaviour deficits in children with FASD and provide further evidence of the specificity of these deficits. On a societal level, more efforts and resources should be focused on recognizing and diagnosing FASD and supporting communication skills, daily living skills and most of all social skills across diagnostic groups within FASD. Without adequate intervention, adolescents and young adults with FASD run a great risk of marginalization and social maladjustment, costly not only to society but also to the lives of the many young people with FASD. © Springer-Verlag 2012

  1. Why are adolescents violent?

    Directory of Open Access Journals (Sweden)

    James Garbarino

    Full Text Available This article discusses how adolescents become violent from the perspective of human development, in which the process of formation of the child and the youth depends on diverse biological, psychological e social variables that constitute the context of life of these individuals. The ecological perspective of human development opposes simple cause-effect relations between antisocial adversities and behaviors and believes that factors such as gender, temperament, cognitive ability, age, family, social environment and culture combine in a complex way influencing the behavior of the child and the adolescent. Some conclusions point to the fact that violence in adolescence usually starts from a combination of early difficulties in relationships associated with a combination of temperamental difficulties. It is concluded that the young seem to be as bad as the social environment surrounding them.

  2. Adolescent Idiopathic Scoliosis

    Directory of Open Access Journals (Sweden)

    Safak Ekinci

    2014-06-01

    Full Text Available Scoliosis is called idiopathic when no other underlying disease can be identified. The etiology of adolescent idiopathic scoliosis (AIS is still unknown despite many years of research effort. Theories on AIS's etiology have included mechanical, hormonal, metabolic, neuromuscular, growth, and genetic abnormalities. Skeletally immature patients with adolescent idiopathic scoliosis are at risk of curve progression. The adolescent onset of severe idiopathic scoliosis has traditionally been evaluated using standing posteroanterior radiographs of the full spine to assess lateral curvature with the Cobb method. Scoliosis in children of school age and above primarily occurs in girls. The therapeutic goal in children is to prevent progression. In children, scoliosis of 20 and deg; or more should be treated with a brace, and scoliosis of 45 and deg; or more with surgery. [Arch Clin Exp Surg 2014; 3(3.000: 174-182

  3. Alcohol consumption in adolescents

    Directory of Open Access Journals (Sweden)

    Ilona Plevová

    2016-03-01

    Full Text Available Aim: To determine the level of alcohol consumption in a selected group of adolescents. Design: A descriptive cross-sectional study. Methods: The data were obtained using a part of the standardized ESPAD questionnaire for assessing consumption of alcoholic beverages. The sample comprised 422 students from seven secondary schools of different types in the city of Ostrava. For statistical analysis, the chi-squared test and Fisher's exact test (for n ≤ 5 were used. The data were processed using Stata v. 10. Results: More than half of respondents first tried alcohol before the age of 15. The most frequent alcohol-related problems were unprotected sex, decreased school performance and problems with parents or friends. Incomplete families were found to be an important factor in adolescents preferring and more frequently drinking beer. Conclusion: The study confirmed results reported by the Europe-wide survey ESPAD, namely that adolescents start to drink alcohol as early as before they turn fifteen.

  4. Physical activity among adolescents

    DEFF Research Database (Denmark)

    Henriksen, P W; Ingholt, L; Rasmussen, M

    2016-01-01

    The objectives of this study were (a) to examine the association between various kinds of parental social support and adolescents' physical activity (PA) and (b) to examine whether various kinds of social support from mothers and fathers were differently associated with boys' and girls' PA. Data...... during leisure time. We used logistic regression analyses to estimate the associations for girls and boys separately, adjusted by age group, parents' occupational social class, family structure, and migration status. There were significant and graded associations between adolescents' PA and all four...... dimensions of parental support for PA. The association patterns were similar for mothers' and fathers' social support and similar for girls and boys. Social processes in the family are important for adolescents' participation in PA. It is important to continue to explore these social processes in order...

  5. Breakfast frequency among adolescents

    DEFF Research Database (Denmark)

    Pedersen, Trine Pagh; Holstein, Bjørn E; Damsgaard, Mogens Trab

    2016-01-01

    , quality of family communication and family support. Further, analyses suggested that the associations were more pronounced among girls, immigrants and adolescents from other family structure than traditional. The study highlights the importance of the family setting in promoting regular breakfast......OBJECTIVE: To investigate (i) associations between adolescents' frequency of breakfast and family functioning (close relations to parents, quality of family communication and family support) and (ii) if any observed associations between breakfast frequency and family functioning vary...... (n 3054) from a random sample of forty-one schools. RESULTS: Nearly one-quarter of the adolescents had low breakfast frequency. Low breakfast frequency was associated with low family functioning measured by three dimensions. The OR (95 % CI) of low breakfast frequency was 1·81 (1·40, 2...

  6. Risk factors of suicidal ideation among adolescents after Wenchuan earthquake in China.

    Science.gov (United States)

    Ran, Mao-Sheng; Zhang, Zhen; Fan, Mei; Li, Rong-Hui; Li, Yuan-Hao; Ou, Guo Jing; Jiang, Zhe; Tong, Yu-Zhen; Fang, Ding-Zhi

    2015-02-01

    Suicidal ideation is a common phenomenon in survivors after disaster event. To identify the change of suicidal ideation, and to test hypotheses concerning the suicidal ideation, depression and PTSD symptoms among adolescent survivors after the 2008 Wenchuan earthquake in China. The suicidal ideation among high school students at 6, 12 and 18 months after the Wenchuan earthquake were investigated. Subjects included 737 student survivors in an affected high school. The PTSD Checklist-Civilian Version (PCL-C) and the Chinese Beck Depression Inventory (C-BDI) were used to measure the symptoms of PTSD and depression. The rates of suicidal ideation among the adolescent survivors at 6-, 12- and 18-month after the earthquake were 35.6%, 35.6% and 30.7% respectively. Depression symptoms in the 18-month follow-up, suicidal ideations at 6 and 12 months after the earthquake were the independent risk factors of suicidal ideation in the 18-month follow-up. Depression symptoms were the strongest predictor of suicidal ideation after earthquake. An increased rate of suicidal ideation after the earthquake may be mainly due to depression but not to PTSD symptoms. The disaster-related psychological sequelae and the risk factors of suicidal ideation, especially depression symptoms, should be considered in the mental health services and suicide prevention. Copyright © 2014 Elsevier B.V. All rights reserved.

  7. Aspergilosis necrotizante crónica en un paciente con secuelas de tuberculosis pulmonar Chronic necrotizing aspergillosis in a patient with pulmonary tuberculosis sequelae

    Directory of Open Access Journals (Sweden)

    Alcides Zambrano F

    2007-03-01

    Full Text Available Aspergillus fumigatus puede causar diferentes patologías en el ser humano: aspergiloma, aspergilosis broncopulmonar alérgica, aspergilosis necrotizante crónica, aspergilosis invasora. En la aspergilosis necrotizante crónica hay invasión local del parénquima y destrucción. A diferencia de la aspergilosis invasora no invade vasos sanguíneos ni se disemina a otros órganos. La aspergilosis necrotizante crónica se presenta en pacientes de edad media o ancianos con patología pulmonar previa: EPOC, secuelas de tuberculosis, resección pulmonar, neumoconiosis, radioterapia, infarto pulmonar o sarcoidosis. La clínica es indolente e inespecífica, con fiebre, tos, expectoración y baja de peso. Se desconoce la incidencia de aspergilosis necrotizante crónica en nuestro medio. La aspergilosis necrotizante crónica es potencialmente fatal, por lo que requiere de un diagnóstico y tratamiento oportuno. Creemos que, debe considerarse esta entidad ante un cuadro consuntivo y febril prolongado, en pacientes con enfermedades predisponentes que producen una leve baja de la inmunidad. Describimos el caso de un paciente atendido en el Instituto Nacional del TóraxAspergillus fumigatus is the causative agent of differents pathologies in the human being: aspergilloma, allergic bronchopulmonary aspergillosis, chronic necrotizing aspergillosis and invasive aspergillosis. In chronic necrotizing aspergillosis there is local invasion of the lung tissue and parenchyma destruction. Chronic necrotizing aspergillosis is different from invasive aspergillosis, because the abscence of vascular invasion or dissemination. Chronic necrotizing aspergillosis is seen in middle-aged and elderly with underlying lung diseases: COPD, tuberculosis sequelae, lung resection, pneumoconiosis, radiotherapy, lung infarction or sarcoidosis. Clinical manifestations are non specific, being the most usual fever, cough, sputum production and weight loss. Incidence of chronic necrotizing

  8. Clinic-epidemiological evaluation of ulcers in patients with leprosy sequelae and the effect of low level laser therapy on wound healing: a randomized clinical trial

    Directory of Open Access Journals (Sweden)

    Barreto Josafá G

    2010-08-01

    Full Text Available Abstract Background Mycobacterium leprae is the only pathogenic bacteria able to infect peripheral nerves. Neural impairment results in a set of sensitive, motor and autonomic disturbances, with ulcers originating primarily on the hands and feet. The study objectives were to analyze the clinic-epidemiological characteristics of patients attended at one specialized dressing service from a leprosy-endemic region of the Brazilian Amazon and to evaluate the effect of low level laser therapy (LLLT on wound healing of these patients. Methods Clinic-epidemiological evaluation of patients with leprosy sequelae was performed at the reference unit in sanitary dermatology of the state of Pará in Brazil. We conducted anamnesis, identification of the regions affected by the lesions and measurement of ulcer depth and surface area. After that, we performed a randomized clinical trial. Fifty-one patients with ulcers related to leprosy were evaluated, twenty-five of them were randomly assigned to a low level laser therapy group or a control group. Patients were treated 3 times per week for 12 weeks. Outcome measures were ulcer surface area, ulcer depth and the pressure ulcer scale for healing score (PUSH. Results Ninety-seven ulcers were identified, with a mean (SD duration of 97.6 (111.7 months, surface area of 7.3 (11.5 cm2, and depth of 6.0 (6.2 mm. Statistical analysis of the data determined that there were no significant differences in the variables analyzed before and after treatment with low level laser therapy. Conclusions Ulcers in patients with leprosy remain a major source of economic and social losses, even many years after they have been cured of M. leprae infection. Our results indicate that it is necessary to develop new and more effective therapeutic tools, as low level laser therapy did not demonstrate any additional benefits to ulcer healing with the parameters used in this study. Trial Registration The trial was registered at Clinical

  9. [Adolescence and AIDS].

    Science.gov (United States)

    1991-01-01

    The myths and prejudices that distort the reality and hide the true causes and effects of natural and social phenomena related to sexuality have a fertile ground in AIDS, given its obvious link to sex. The alarming spread of AIDS has been 1 result of these myths and prejudices. Human beings are sexual by nature; genital organs determine sex and also induce sexual behavior. It is by not fairly well accepted that an individual's sexuality exists from birth. Puberty usually begins at 12-16 years for both sexes. The physical changes of puberty terminate in the ability of the female to conceive and the male to procreate. The sexual excitation of adolescents resulting from production of various hormones can only be eliminated by some type of sexual satisfaction or sublimation. Sexuality, according to Freud, is an organizing principle of the personality. The sexual organs exist not merely for reproduction but to provide pleasure. Puberty signifies entry into active sex life. But the ideological structure of society, perpetuated by the family, schools, religion, the mass media, and other social institutions, sends confused signals to adolescents, requiring abstinence and virginity until marriage for women while encouraging sexual adventures for men. Adolescents are confronted by their new sexual feelings in the midst of a virtual bombardment of visual sexual stimuli from the mass media. It becomes impossible for adolescents to satisfy the requirements of appearances while also resolving the problems and pressures of their newly gained sexual maturity. Many adolescents become sexually active, and the problem is not to prevent sexual activity but to improve the conditions under which it occurs. Adolescents, lacking education and information about sex, begin their sex lives without protection. AIDS has now been added to the list of dire consequences that can result. A true sex education beginning in the home is needed to enable young people to develop healthy and full sex

  10. Adolescent rampant caries

    Directory of Open Access Journals (Sweden)

    Namita

    2012-01-01

    Full Text Available Adolescent rampant caries is a new and growing challenge in Conservative Dentistry. It has the same etiology and pattern as that of nursing bottle syndrome. Herein, a case is presented in which the main cause of rampant caries is the patient′s habit of keeping cariogenic food in her mouth and going to sleep. Educating this etiology and introduction of preventive strategies not only assists in meeting the special oral needs of the adolescent population, but also helps to establish lifelong healthful habits.

  11. Clinical aspects of obesity in childhood and adolescence.

    Science.gov (United States)

    Kiess, W; Galler, A; Reich, A; Müller, G; Kapellen, T; Deutscher, J; Raile, K; Kratzsch, J

    2001-02-01

    The level of fatness of a child at which morbidity acutely and/or later in life increases is determined on an acturial basis. Direct measurements of body fat content, e.g. hydrodensitometry, bioimpedance, or DEXA, are useful tools in scientific studies. However, body mass index (BMI) is easy to calculate and is generally accepted now to be used to define obesity in children and adolescents clinically. An increased risk of death from cardiovascular disease in adults has been found in subjects whose BMI had been greater than the 75th percentile as adolescents. Childhood obesity seems to substantially increase the risk of subsequent morbidity whether or not obesity persists into adulthood. The genetic basis of childhood obesity has been elucidated to some extent through the discovery of leptin, the ob gene product, and the increasing knowledge on the role of neuropeptides such as POMC, neuropeptide Y (NPY) and the melanocyte concentrating hormone receptors (for example, MC4R). Environmental/exogenous factors largely contribute to the development of a high degree of body fatness early in life. Twin studies suggest that approximately 50% of the tendency toward obesity is inherited. There are numerous disorders including a number of endocrine disorders (Cushing's syndrome, hypothyroidism, etc.) and genetic syndromes (Prader-Labhard-Willi syndrome, Bardet Biedl syndrome, etc.) that can present with obesity. A simple diagnostic algorithm allows for the differentiation between primary or secondary obesity. Among the most common sequelae of primary childhood obesity are hypertension, dyslipidemia, back pain and psychosocial problems. Therapeutic strategies include psychological and family therapy, lifestyle/behaviour modification and nutrition education. The role of regular exercise and exercise programmes is emphasized. Surgical procedures and drugs used in adult obesity are still not generally recommended in children and adolescents with obesity. As obesity is the most

  12. 神经干细胞移植等方法治疗脑梗死后遗症的策略研究%Strategy study of treatment for cerebral infarction sequelae using neural stem cell transplantation

    Institute of Scientific and Technical Information of China (English)

    陈小玉; 段云霞; 方亮; 张梓倩; 刘庆山

    2011-01-01

    背景:国内外动物模型的研究已经表明干细胞移植对脑梗死的治疗可以起到积极作用,在行为恢复和缩小梗死面积临床试验也有一定的成果.目的:通过分析和总结2000年以来国内外多种方法治疗脑梗死后遗症的研究,探讨各疗法的优缺点,寻求最佳的治疗途径.方法:分别以"脑梗死后遗症、脑卒中后遗症"," Cerebral infarction sequelae hemiplegia"等为检索词,应用计算机检索万方数据知识服务平台及Pubmed 数据库2000-01/2010-10有关文章,保留22篇文献做进一步分析.结果与结论:神经干细胞治疗脑梗死后遗症的方法主要集中在外源性神经干细胞移植后整合、补充或替代受损及内源性神经干细胞损伤后在细胞因子等的作用下激活修复.神经保护疗法主要是针对缺血性级联反应的各种通路,保护因缺血、缺氧而受损伤但仍有活力的神经元,逆转半暗带,降低再灌注损伤对脑神经细胞的损伤,减少梗死面积,进行有针对性的治疗.理疗及功能康复、民族药物多种方法的应用也为脑梗死后遗症的治疗带来了希望.其中调节在体神经干细胞增殖和分化,促进神经系统的功能修复是未来药物研究的重要研究目标.%BACKGROUND: Studies have demonstrated that stem cell transplantation plays a positive role in treatment of cerebral infarction,which also has good outcome in recovery and diminution of infarct size in clinical trials.OBJECTIVE: By analyzing and summarizing the research which adopts treatment of cerebral infarction sequelae in past ten years,we devote to discuss the strength and weakness of those treatments and find a suitable treatment of cerebral infarction sequelae.METHODS: Application of computer technology to retrieve the articles in wanfang data and PubMed database on spinal cord tissue engineering from 2000 January to 2010 October. Words for retrieve were "cerebral infarction sequelae, neural stem cells

  13. 电针联合脑活素注射液治疗面神经炎后遗症的疗效分析%Effective analysis of treating sequelae of facial paralysis by EA plus cerebrolysin vial

    Institute of Scientific and Technical Information of China (English)

    陈慧铿

    2015-01-01

    目的:观察电针联合脑活素注射液治疗面神经炎后遗症的临床疗效.方法:将我院针灸科住院及门诊90例面神经炎后遗症患者随机分为联合治疗组(A组)、电针组(B组)及脑活素注射液组(C组),每组30例.观察周期为2个月,评价三组患者治疗前后的疗效.结果:A组疗效明显高于B组和C组,经统计学处理,差异具有统计学意义(P<0.01).结论:电针联合脑活素注射液能明显改善面神经炎后遗症的临床症状.%Objective: To observe the clinical efficacy of acusector combined with cerebrolysin vial of curing facial neuritis sequela. Methods:Ninety patients with facial neuritis sequela were randomly assigned into 3 groups: A group is Combination therapy group (acusector combined with cerebrolysin vial), B group is acusector group, and C group is cerebrolysin vial group. After 2 mouths,evaluation of the efficacy of the three groups before and after the treatment. Results:The effect of A group was significantly higher than that of B group and C group,by statistically, the difference was statistically significant (P < 0.01). Conclusion: Acusector combined with cerebrolysin vial can obviously improve the clinical symptoms of the facial neuritis sequela.

  14. Cost-effectiveness Analysis of 2 Therapeutic Schemes for Apoplexy Sequela%2种治疗方案治疗中风后遗症的成本-效果分析

    Institute of Scientific and Technical Information of China (English)

    胡孔友; 陈际连; 蔡越冬

    2012-01-01

    OBJECTIVE: To analyze and evaluate the cost-effectiveness of Compound danshen tablets and Citicoline sodium injection in the treatment of apoplexy sequela. METHODS: 104 cases of apoplexy sequela were randomly divided into group A (Compound danshen tablets, 54 cases) and group B (Citicoline sodium injection, 50 cases). Cost-effectiveness analysis was conducted with the pharmacoeconomic method. RESULTS: The cost was 48 yuan in Compound danshen tablets group and 1 632 yuan in Citicoline sodium injection group. The effective rates were 83% and 80% , and the CIE were 0.58 and 20.4, respectively. Referred to group A, the incremental cost effectiveness ratios were -528. CONCLUSION: Compound danshen tablets have well curative effect and low cost in the treatment of apoplexy sequela.%目的:评价复方丹参片与胞磷胆碱钠注射液治疗中风后遗症的经济学效果.方法:将104例中风后遗症患者,随机分为A组(复方丹参片,54例)和B组(胞磷胆碱钠注射液,50例),观察2组的临床效果,并运用药物经济学比较其成本-效果.结果:A组治疗成本为48元,有效率为83%;B组治疗成本为1 632元,有效率为80%,2组成本-效果比分别为0.58和20.4.以A组为参照的增量成本-效果比为-528.结论:与胞磷胆碱钠注射液比较,复方丹参片治疗中风后遗症疗效相当,但经济性较好.

  15. Adolescent Pregnancy: A Challenge for Counselors.

    Science.gov (United States)

    Foster, Carolyn D.; Miller, Gary M.

    1980-01-01

    Adolescent pregnancy has medical, psychological, sociological and educational repercussions. The counselor's objective is to assist the adolescent in developing adaptive mechanisms for dealing with adolescence and pregnancy and to integrate the two conditions into a growth-producing situation. (Author)

  16. Genetics Home Reference: adolescent idiopathic scoliosis

    Science.gov (United States)

    ... Home Health Conditions adolescent idiopathic scoliosis adolescent idiopathic scoliosis Printable PDF Open All Close All Enable Javascript ... view the expand/collapse boxes. Description Adolescent idiopathic scoliosis is an abnormal curvature of the spine that ...

  17. Early adolescent sexual debut in peer networks

    NARCIS (Netherlands)

    Savickaite, Ruta; Dijkstra, Jan; Veenstra, René

    2016-01-01

    Emerging adolescent sexual activity is considered a normative aspect of adolescent development and the transition to adulthood, however, there are potential risks involved when adolescents start having sex, such as teenage pregnancies, sexually transmitted infections, and undesirable long-term

  18. Brief Intervention Helps Adolescents Curb Substance Use

    Science.gov (United States)

    ... Helps Adolescents Curb Substance Use Brief Intervention Helps Adolescents Curb Substance Use Email Facebook Twitter Two hour- ... School, in Minneapolis, conducted the trial with 315 adolescent and parent/caregiver pairs. Their findings strengthen evidence, ...

  19. [Adolescent psychosocial development].

    Science.gov (United States)

    Gaete, Verónica

    2015-01-01

    It is increasingly necessary that pediatricians have greater knowledge of adolescent health. To begin with they should be familiar with the psychosocial development of this period, an issue which is imperative for the health care of the age group. With that purpose, this article reviews the normal adolescent psychosocial development. Adolescence is a stage that has been progressively prolonged, during which fast and big changes occur, that lead human beings to become biologically, psychologically and socially mature, and potentially able to live independently. Developmental tasks of this period are the establishment of identity and the achievement of autonomy. Although it is a process of high individual variability in terms of its beginning and end, the progression through stages, the synchrony of development between the various areas, and in other aspects, the psychosocial development of this period usually have common characteristics and a progressive pattern of 3 phases: early, middle and late adolescence. Psychological, cognitive, social, sexual and moral development of young people in each of them are described in this article. Copyright © 2015 Sociedad Chilena de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved.

  20. Adolescence: Season of Transition.

    Science.gov (United States)

    Philibert, Paul J.

    1982-01-01

    Delineates Sigmund Freud's theories of symbolic relations, Jean Piaget's theories of cognitive development, and Eric Erickson's concept of identity crisis to analyze and explain the characteristics and phenomena of adolescent development. Suggests roles and tasks for teachers and parents in promoting healthy development. (WL)

  1. Adolescents and Graffiti.

    Science.gov (United States)

    Kan, Koon-Hwee

    2001-01-01

    Describes the different types of graffiti: (1) private forms of graffiti (doodling and latrinalia); and (2 public forms (gang graffiti, tags, and pieces). Uses teenage psychology to interpret adolescents' involvement in graffiti. Examines graffiti art in relation to its educational implications for secondary art education. (CMK)

  2. Adolescent Development: Body Blues.

    Science.gov (United States)

    Yates, Alayne; Brodkin, Adele M.

    1994-01-01

    When early adolescents equate body image with self-image, they risk eating and exercise disorders, with dangerous results. Interviews with two experts present information to help middle school teachers understand the problem and intervene with students whose preoccupation with appearance or prowess can, taken to the extreme, be fatal. (SM)

  3. Problems of adolescence

    CERN Multimedia

    Feldmann

    1968-01-01

    Le Prof.Feldmann, Prof. de psychiatrie à l'Université de Genève, donne une suite de la conférence du novembre 1967 en parlant des besoins de l'adolescent et l'aspect pratique, suivi d'une discussion

  4. Adolescent Sociopaths. Revised.

    Science.gov (United States)

    Chapple, Eliot D.

    Presented is the final report of a research project on the programed training and placement of nonpsychotic disturbed adolescents. Eleven chapters cover topics which include the following: psychiatry and the sociopaths and psychopaths; boys dealt with in the project; development of the programed interaction diagnostic interview; disturbances to…

  5. From birth to adolescence

    DEFF Research Database (Denmark)

    Pietrobelli, A; Flodmark, C E; Lissau, I

    2005-01-01

    that despite the fact that childhood obesity is a crisis facing worldwide youth, it is necessary that action to control it must be taken now. All the six relevant levels (ie, family, schools, health professionals, government, industry and media) could be involved in prevention of child and adolescent obesity....

  6. Abortion among Adolescents.

    Science.gov (United States)

    Adler, Nancy E.; Ozer, Emily J.; Tschann, Jeanne

    2003-01-01

    Reviews the current status of abortion laws pertaining to adolescents worldwide, examining questions raised by parental consent laws in the United States and by the relevant psychological research (risk of harm from abortion, informed consent, consequences of parental involvement in the abortion decision, and current debate). Discusses issues…

  7. Psychopathological Development across Adolescence

    Science.gov (United States)

    Rutter, Michael

    2007-01-01

    Daniel Offer's seminal writings in the 1960s led to a realization that normal adolescence was not characterized by turmoil and upheaval, the then prevailing view that derived from studies of clinical samples. In this paper, the research findings that have appeared over the last four decades are reviewed with respect to the overall features of…

  8. The Adolescent Suicide Problem.

    Science.gov (United States)

    Maris, Ronald

    1985-01-01

    The suicide rate of young people in the United States rose 237 percent between 1960 and 1980. This paper addresses three related issues: epidemic versus artifact; stress in adolescence; and the distinctive traits of the lifestyles or careers of a random sample of young Chicago suicides. (Author/BL)

  9. Internet Addiction among Adolescence

    Science.gov (United States)

    Sargin, Nurten

    2012-01-01

    Each innovation brings along many risks. One of the risks related with the Internet use is Internet addiction. The aim of this study is to examine Internet addiction in adolescence in terms of gender, Internet access at home and grades. The research design used was survey method. The study population consisted of second stage students attending…

  10. Entrepreneurship and Adolescents

    Science.gov (United States)

    Santana Vega, Lidia E.; González-Morales, Olga; Feliciano García, Luis

    2016-01-01

    This work studied the entrepreneurial aspirations of 3,987 adolescents regarding self-employment and the influence of gender, age, nationality, type of school, location of the school, educational level and performance. The Logit model is used to analyze the data. The results indicate that the pupils' aspirations to be self-employed increase in the…

  11. Governing Adolescent Drinking

    Science.gov (United States)

    Jarvinen, Margaretha; Ostergaard, Jeanette

    2009-01-01

    This article examines the relationship between the drinking habits of Danish adolescents and the upbringing ideals and alcohol rules of their parents. It is based on three different data sets: a survey of 2,000 Danish young people born in 1989, a survey with the parents of these young people, and two waves of focus group interviews (in all 28)…

  12. Adolescent Substance Abuse.

    Science.gov (United States)

    Thorne, Craig R.; DeBlassie, Richard R.

    1985-01-01

    Cummings (1979), citing evidence from the National Institute of Drug Abuse, reports that one of every eleven adult Americans suffers from a severe addictive problem. Drug addiction is epidemic among teenagers; one of every six teenagers suffers from a severe addictive problem. This paper focuses on adolescent drug/substance abuse. (Author)

  13. Victimization of Obese Adolescents

    Science.gov (United States)

    Robinson, Sabrina

    2006-01-01

    Peer victimization of obese adolescents has been associated with low self-esteem, body dissatisfaction, social isolation, marginalization, poor psychosocial adjustment, depression, eating disorders, and suicidal ideation and attempts, not to mention poor academic performance. Weight-based peer victimization is defined as unsolicited bullying and…

  14. Adolescent Loneliness Assessment

    Science.gov (United States)

    de Minzi, Maria Cristina Richaud; Sacchi, Carla

    2004-01-01

    The aim of the present work was to develop a loneliness scale for adolescents in order to assess their perceptions of the quality of their relationships with parents and peers. The scale was administered to 1,233 Argentine secondary school students, aged 13-16 years. Factor analyses (principal axes, oblimin solution) were conducted. Four factors…

  15. Moral Development in Adolescence

    Science.gov (United States)

    Hart, Daniel; Carlo, Gustavo

    2005-01-01

    Themes in the papers in this special issue of the "JRA" on moral development are identified. We discuss the intersection of moral development research with policy concerns, the distinctive qualities of moral life in adolescence that warrant investigation, the multiple connotations of "moral", the methods typical of moral development research, and…

  16. Assessments of adolescent language.

    Science.gov (United States)

    Wiig, E H

    1995-02-01

    I have stressed that language and learning disabilities that are exhibited in the preschool or elementary school years often persist into adolescence but that the characteristics and implications of these disabilities change with the preadolescent and adolescent transitions to metalinguistic maturity. As the student with language disabilities matures and as educational demands increase in complexity and in level of abstractness, the interactions between language and cognition become more apparent. Language disabilities of adolescents are often described in relation to observed deficits in the acquisition of content (semantics), form (morphology and syntax), and use (pragmatics). I have broadened this perspective to consider identification of metalinguistic strengths and/or deficits, deficits in the integration and organization of communication, reasoning and problem solving, and in conceptualization and creativity. Several assessment options were discussed, among them, norm-and criterion- referenced testing, language sample analysis, portfolio assessments of integrated communication, observational checklists and interviews, classroom language probes, and self-assessments. The perspectives taken for assessment have been that no single assessment option can satisfy all assessment objectives and/or constraints. I have also stressed that all tests are subject to measurement error and how to account for this error. Last, but not least, I have shared some of the voices of adolescents which express their perspectives and priorities.

  17. Adolescent to Parent Violence.

    Science.gov (United States)

    Cornell, Claire Pedrick; Gelles, Richard J.

    1982-01-01

    Examines the extent of violence toward parents by adolescent children in relation to: (1) sex and age of the child; (2) the likelihood that mothers, more than fathers, are victims of children's violence; (3) social factors that may influence child to parent violence; and (4) stress as a factor in family violence. (Author/MJL)

  18. Adolescent alcohol use

    DEFF Research Database (Denmark)

    Bendtsen, Pernille; Damsgaard, Mogens Trab; Huckle, Taisia

    2014-01-01

    AIMS: To analyse how adolescent drunkenness and frequency of drinking were associated with adult drinking patterns and alcohol control policies. DESIGN, SETTING AND PARTICIPANTS: Cross-sectional survey data on 13- and 15-year-olds in 37 countries who participated in the Health Behaviour in School...

  19. Spinal pain in adolescents

    DEFF Research Database (Denmark)

    Aartun, Ellen; Hartvigsen, Jan; Wedderkopp, Niels

    2014-01-01

    BACKGROUND: The severity and course of spinal pain is poorly understood in adolescents. The study aimed to determine the prevalence and two-year incidence, as well as the course, frequency, and intensity of pain in the neck, mid back, and low back (spinal pain). METHODS: This study was a school...

  20. Internet Addiction among Adolescence

    Science.gov (United States)

    Sargin, Nurten

    2012-01-01

    Each innovation brings along many risks. One of the risks related with the Internet use is Internet addiction. The aim of this study is to examine Internet addiction in adolescence in terms of gender, Internet access at home and grades. The research design used was survey method. The study population consisted of second stage students attending…

  1. Nutritional disturbances by adolescent

    OpenAIRE

    Stassart, Martine

    2011-01-01

    The nutritional disturbances are frequent by adolescents. That is a psychological defense against dependance toward the mother but also a middle to remain in a childish position i.e. either as a fat baby - in the fall of obesity- or as the ideal pre- or bisexual great child - in the case of anorexia.

  2. Abortion among Adolescents.

    Science.gov (United States)

    Adler, Nancy E.; Ozer, Emily J.; Tschann, Jeanne

    2003-01-01

    Reviews the current status of abortion laws pertaining to adolescents worldwide, examining questions raised by parental consent laws in the United States and by the relevant psychological research (risk of harm from abortion, informed consent, consequences of parental involvement in the abortion decision, and current debate). Discusses issues…

  3. Current perspectives in the USA on the diagnosis and treatment of pelvic inflammatory disease in adolescents

    Directory of Open Access Journals (Sweden)

    Risser WL

    2017-06-01

    Full Text Available William L Risser,1 Jan M Risser,2 Amanda L Risser3 1Department of Pediatrics, University of Texas Medical School, 2Division of Epidemiology, University of Texas School of Public Health, Houston, TX, 3Department of Family Medicine, Oregon Health and Sciences University, Portland, OR, USA Abstract: In this review, the epidemiology, diagnosis, and treatment of pelvic inflammatory disease (PID are discussed from a USA perspective and the difficulties that USA adolescents face in recognizing and seeking care for PID and other sexually transmitted infections (STIs are emphasized. Females aged 15–24 years have the highest incidence of cervical infection with Chlamydia trachomatis and Neisseria gonorrheae, the principal causes of PID. PID is common in this age group. However, the incidence of PID in the USA is not known, because it is not a reportable disease, and because clinicians vary in the criteria used for the diagnosis. The Centers for Disease Control and Prevention (CDC recommended the following diagnostic criteria that include lower abdominal or pelvic pain and at least one of the following: adnexal tenderness or cervical motion tenderness or uterine tenderness. Because PID can have serious sequelae, the criteria emphasize sensitivity (few false-negatives at the expense of specificity (some false-positives. Patients who have PID are usually treated in the outpatient setting, following the CDC’s Guidelines for the Treatment of Sexually Transmitted Diseases 2015. They receive one dose of an intramuscular cephalosporin, together with 2 weeks of oral doxy cycline, and sometimes oral metronidazole. Improvement should usually be evident in 3 days. The USA does not offer comprehensive sex education for adolescents in public or private schools. Adolescents are unlikely to recognize the symptoms of PID and seek medical treatment. Confidentiality is important to adolescents, and low cost or free sources of confidential care are uncommon, making it

  4. Cesarean Delivery in Adolescents.

    Science.gov (United States)

    Katz Eriksen, Jennifer L; Melamed, Alexander; Clapp, Mark A; Little, Sarah E; Zera, Chloe

    2016-10-01

    To examine the effect of maternal age on indication for primary cesarean delivery in low-risk nulliparous women. Retrospective cohort study. Urban academic tertiary care center. Nulliparous women younger than 35 years of age delivering vertex-presenting singletons at term. Participants underwent spontaneous, operative or cesarean delivery. Mode of delivery, indication, and timing of cesarean delivery. Adolescents were half as likely to undergo cesarean delivery overall (odds ratio [OR], 0.48; 95% confidence interval [CI], 0.43-0.54), and more than one-third less likely to undergo cesarean delivery in labor (OR, 0.59; 95% CI, 0.53-0.66). Adjustment for potential confounders did not alter the strength of these associations. Adolescents were half as likely to undergo cesarean delivery for failure to progress (OR, 0.49; 95% CI, 0.43-0.54). There was no difference in the odds of cesarean delivery for nonreassuring fetal status (OR, 0.91; 95% CI, 0.77-1.06), or genital herpes (OR, 1.44; 95% CI, 0.57-3.68). Induction, macrosomia, oxytocin augmentation, and any labor complication were all associated with increased risk of cesarean delivery. There was no difference in the duration of second stage for adolescents who delivered by cesarean delivery compared with adults (240.0 vs 237.7 minutes; P = .84), but adolescents who delivered vaginally had a second stage that was one-third shorter than adults (62.5 vs 100.3 minutes; P cesarean delivery overall, and 40% less likely to undergo a primary cesarean delivery in labor, even after adjustment for multiple maternal, neonatal, and labor characteristics. This difference is not explained by differences in the duration of the second stage of labor. Copyright © 2016 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

  5. Intergenerational influence on adolescents' proenvironmental behavior

    National Research Council Canada - National Science Library

    Liu, Chunlin; Li, Jianan

    2016-01-01

    .... That is, the relationship between informational influence and adolescents' proenvironmental behavior became stronger when adolescents perceived higher levels of parental power, with the opposite...

  6. INTERGENERATIONAL INFLUENCE ON ADOLESCENTS' PROENVIRONMENTAL BEHAVIOR: 1

    National Research Council Canada - National Science Library

    Jianan Li; Chunlin Liu

    2016-01-01

    .... That is, the relationship between informational influence and adolescents' proenvironmental behavior became stronger when adolescents perceived higher levels of parental power, with the opposite...

  7. Efeitos da facilitação neuromuscular proprioceptiva na estabilidade postural e risco de quedas em pacientes com sequela de acidente vascular encefálico: estudo piloto Efectos de la facilitación neuromuscular propioceptiva en la estabilidad postural y riesgo de caídas en pacientes con secuela de accidente vascular encefálico: estudio piloto Effects of proprioceptive neuromuscular facilitation in postural stability and risk of falls in patients with sequelae of stroke: pilot study

    OpenAIRE

    Natália Noman de Lacerda; Érika Baptista Gomes; Hudson Azevedo Pinheiro

    2013-01-01

    O controle do tronco é uma habilidade motora básica necessária para executar diversas tarefas funcionais, e é deficiente em pacientes que sofreram acidente vascular encefálico (AVE). Objetivo: Avaliar o efeito do método facilitação neuromuscular proprioceptiva (PNF) na estabilidade postural e risco de quedas em pacientes com sequela de AVE. Metodologia: Foi realizado estudo de intervenção que consistiu em treinamento da estabilidade postural por meio de um protocolo fixo constituído por 5 exe...

  8. Efeitos da facilitação neuromuscular proprioceptiva na estabilidade postural e risco de quedas em pacientes com sequela de acidente vascular encefálico: estudo piloto Efectos de la facilitación neuromuscular propioceptiva en la estabilidad postural y riesgo de caídas en pacientes con secuela de accidente vascular encefálico: estudio piloto Effects of proprioceptive neuromuscular facilitation in postural stability and risk of falls in patients with sequelae of stroke: pilot study

    OpenAIRE

    Natália Noman de Lacerda; Érika Baptista Gomes; Hudson Azevedo Pinheiro

    2013-01-01

    O controle do tronco é uma habilidade motora básica necessária para executar diversas tarefas funcionais, e é deficiente em pacientes que sofreram acidente vascular encefálico (AVE). Objetivo: Avaliar o efeito do método facilitação neuromuscular proprioceptiva (PNF) na estabilidade postural e risco de quedas em pacientes com sequela de AVE. Metodologia: Foi realizado estudo de intervenção que consistiu em treinamento da estabilidade postural por meio de um protocolo fixo constituído por 5 exe...

  9. Poliomyelitis sequela in Pizhou city%邳州市小儿麻痹后遗症评估分析报告

    Institute of Scientific and Technical Information of China (English)

    许光旭; 顾绍钦; 励建安

    2005-01-01

    科合作的团队,建立集体讨论制度,使这批小儿麻痹后遗症患者的康复功能达到最好的水平.%BACKGROUND: An epidemic outbreak of poliomyelitis occurred in Pizhou City, Jangsu Province, 15 years ago. It is important to appraise the daily living and function of those survived children.OBJECTIVE: To investigate the physical status of the survived children and propose appropriate suggestions on rehabilitation.DESIGN: Case-based cross-sectional study based on patients.SETTING: Department of Rehabilitative Medicine of First Hospital Affiliated to Nanjing Medical University.PARTICIPANTS: Totally 545 patients with poliomyelitis sequela, which was onset in 1989, were found in Qizhou, and 333 of them were randomly selected from the local"New Hope" nursing house and its surrounding areas.All patients were assayed in one week.METHODS: The survey included 333 polio victims in the nursing house or from the surrounding areas. The study was conducted by five research groups, with two physiatrists and one therapist in each group. Assessment included muscle strength, joint rang of motion, limb deformities, activities of daily living, previous surgical interventions and orthosis. The distance was measured from the anterior superior iliac to medial malleolus and from nave to the medial malleolus, respectively. Anatomic length and functional length were also measured.MAIN OUTCOME MEASURES: Major outcomes included the forms,shapes, or functions of foot, pelvic, hip, knee and ankle joints.RESULTS: According to intention-to-treat analyses, 333 patients with poliomyelitis sequela entered the final analysis. Most of them aged from 15 to 17 years old, which accounted for 97%. Totally 135 patients(40.5% )walked independently and 148 (44.4%) walked with-orthsis and/or crutches. The discrepancy was between 0. 5 cm to 13.0 cm. Patients with paraplegia were 112(33.6% ), which was lesser than those with monoplegia (211, 65.8% ). There were 3 cases with quadriplegia and 2

  10. Cannabis Use Disorder in Adolescence.

    Science.gov (United States)

    Simpson, Annabelle K; Magid, Viktoriya

    2016-07-01

    Cannabis use in the adolescent population poses a significant threat of addiction potential resulting in altered neurodevelopment. There are multiple mechanisms of treatment of cannabis use disorder including behavioral therapy management and emerging data on treatment via pharmacotherapy. Recognizing the diagnostic criteria for cannabis use disorder, cannabis withdrawal syndrome, and mitigating factors that influence adolescent engagement in cannabis use allows for comprehensive assessment and management in the adolescent population. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Oxidant/antioxidant status in obese adolescent females with acne vulgaris

    Directory of Open Access Journals (Sweden)

    Abulnaja Khalid

    2009-01-01

    Full Text Available Background and Objectives: Acne vulgaris is a distressing skin condition, which can carry with it significant psychological disability. Oxidant/antioxidant imbalance leads to increased production of free radicals, that cause many diseases. Some nutrients, along with systemic oxidative stress, have been implicated in acne vulgaris. The goal of the present study was to assess oxidant and antioxidant status in correlation with the incidence of acne vulgaris in adolescent obese females. Materials and Methods: A total of 60 adolescent females (age 16-22 years were divided into four groups (15 each as follows: The first included obese females with acne; the second included obese females without acne; the third included non obese with acne and the fourth included non obese without acne. Fasting serum Malondialdehyde (MDA, β-carotene, and Vitamins A, E, and C were measured. In addition, platelet monoamineoxidase (MAO, and erythrocyte catechol-o-methyltransferase (COMT activities were determined. Results: It was found that serum MDA was statistically significantly decreased in obese and non obese subjects with acne, as compared to those without acne ( P < 0.05, P < 0.001 respectively. In contrast, the levels of β-carotene, vitamins A, E and C and the activity of MAO were significantly decreased in the obese and non obese with acne, as against the obese and non obese without acne. Interpretation: In obese subjects, increased fat content facilitates free radical production and lipid peroxidation, as indicated by increased MDA level, which is scavenged by the antioxidant vitamins. The decreased activity of MAO may be inhibited by free radicals and this causes psychological depression in adolescents. However there were non significant changes in the activity of COMT among the studied groups. Conclusion: The nutritional factors and a weakened antioxidant defense system may interplay, to increase the risk of psychological sequelae in acne vulgaris.

  12. Lesões múltiplas de osteoma cutis na face: terapêutica minimamente invasiva em pacientes com sequela de acne - relato de casos Multiple injuries of osteoma skin in the face: therapeutical least invasive in patients with acne sequela - case report

    Directory of Open Access Journals (Sweden)

    Ian Göedert Leite Duarte

    2010-10-01

    Full Text Available Osteoma cutis é a formação óssea no interior da pele, podendo ser primária ou secundária. Única ou múltipla, de tamanhos variados e acometendo ambos os sexos, é uma lesão cutânea rara, de etiopatogenia e classificação ainda discutidas. Nosso objetivo foi relatar o diagnóstico e a terapêutica minimamente invasiva de lesões múltiplas de osteoma cutis na face em pacientes com sequelas de acne. Fizemos a retirada dos osteomas com agulhas BD 0,70 x 25 22G1, sem anestésicos tópicos ou injetáveis no local. As pequenas incisões foram deixadas expostas, com pomada cicatrizante. Obteve-se um excelente resultado estético em 15 dias.Osteoma cutis is a bone formation in the dermis can to be primary or secondary forms. Only, multiples, many forms, occurring on either sex, they are a rare cutaneous disease. The pathogenesis and classification remains unclear. Our objective was the diagnostic and small invasive surgery treatment of the osteoma cutis multiple of the face, in patients as a sequel of acne. To remove the osteoma we used needle BD 0,70x25 22G1, without anesthetic topic or inject able site. The small wounds were exposed with scarring balsam. We got an excellent esthetic result after 15 days.

  13. 血栓通联合吡拉西坦治疗老年性脑梗死后遗症的临床疗效观察%cerebral infarction sequela

    Institute of Scientific and Technical Information of China (English)

    邹永玲

    2015-01-01

    ObjectiveTo research clinical effect by Xueshuantong combined with piracetam in the treatment of senile cerebral infarction sequela.MethodsA total of 120 senile patients with cerebral infarction sequela were randomly divided into experimental group and control group, with 60 cases in each group. The control group received piracetam for treatment, and the experimental group received additional Xueshuantong. National institutes of health stroke scale (NIHSS) and mini-mental state examination (MMSE) were observed in the two groups before and after treatment.ResultsBefore treatment, there was no statistically significant difference of NIHSS and MMSE scores between the two groups (P>0.05). The experimental group had much better NIHSS and MMSE scores after treatment than the control group, and their differences all had statistical significance (P0.05);治疗后,试验组NIHSS及MMSE评分明显优于对照组,差异均具有统计学意义(P<0.05)。结论对于老年性脑梗死后遗症患者采用血栓通联合吡拉西坦治疗可以明显减轻神经功能的缺损,改善精神状态,值得在临床推广。

  14. 超高速碰撞实验中跟进气体对等离子体信号的影响%Influence of the Sequela Gas Accompanied with the Plasma Generated by Hypervelocity Impact

    Institute of Scientific and Technical Information of China (English)

    张东江; 张庆明; 甘云丹; 李一磊

    2011-01-01

    针对二级轻气炮加载铝弹丸超高速碰撞靶板产生等离子体的过程中,弹丸后面跟进气体有可能对等离子体信号造成影响的问题,利用三探针、磁线圈、高温计等实验设备分别对有铝弹丸和无弹丸两发实验进行了诊断测量,得出了相应的电子温度、磁感应强度、物质温度变化曲线.比较实验结果得出:弹丸超高速碰撞靶板产生等离子体的过程中跟进气体信号幅值较小,不会对实验结果造成明显影响.%During the measurement of plasma generated by hypervelocity impact in the two-stage gas gun, the gas following the projectile might disturb the physical measurement of plasma signal. The triple probe, coil and pyrometer were used to detect how much the influence of the sequela gas. By comparison, the results show that the signal value of the sequela gas is relatively small and could not produce obvious influence to the measurement of plasma parameter.

  15. Clinical Progress of Acupuncture and Moxibustion Treating Sequelae Stage of Peripheral Facial Paralysis%周围性面瘫后遗症期针灸治疗的临床进展

    Institute of Scientific and Technical Information of China (English)

    朱城斌

    2014-01-01

    This paper summarizes the diagnosis and treatment of acupuncture and moxibustion for sequelae stage of peripheral facial paralysis in re-cent 10 years, mainly with Yangming meridian of hands and feet and facial acupoint, as well as acupuncture, moxibustion and other methods, acu-puncture and moxibustion treating sequelae stage of peripheral facial paralysis is more effective, but focusing on the clinic and lacking standard thera-peutic schedule.%本文综述近10年针灸治疗周围性面瘫后遗症期的诊疗情况,选穴以手足阳明经和面部穴位为主,治疗多为针刺、灸法等其他方法配合,针灸治疗周围性面瘫后遗症期较有效,但偏于临床且缺乏标准的治疗方案。

  16. Adolescent drinking, social identity, and parenting for safety: Perspectives from Australian adolescents and parents.

    Science.gov (United States)

    Berends, Lynda; Jones, Sandra C; Andrews, Kelly

    2016-03-01

    We explored young people and parents' views on adolescent drinking and safety in the locations where drinking may occur. Focus groups with adolescents and parents showed that many believed adolescent drinking and drunkenness is normative. Younger adolescents had more negative views of adolescent drinkers than their older peers. Adolescent drinking occurred in private settings and parents made decisions about allowing their adolescent children to attend social events based on the level of safety attributed to the location. If adolescent drinking was likely then home was the preferred location as it provided scope for risk minimisation. Positive portrayals of non-drinking adolescents and information to assist parents' decision-making are needed.

  17. Internet mediated adolescent relationships

    Directory of Open Access Journals (Sweden)

    Fabrício de Souza

    2010-06-01

    Full Text Available This paper aims to contribute towards the comprehension of the adhesion of adolescent to digital technologies and their usage in the search for or consolidation of relationships with their peers. The objective was to analyze the role of blogs in the maintenance and establishment of relationships among adolescents from the State of Espírito Santo, Brazil. Three boys’ blogs and three girls’ blogs were selected, and five pages of each blog were selected, in a total of 30 pages. Categories were elaborated from reading the posts left at the 30 pages and subsequently used to classify and quantify the posts. Messages and comments left at the blogs had a positive affective connotation, in search for approximation and contact with the blog owner. Messages were also noted for gender differences. It was concluded that some determined patterns of offline interaction guided the establishment of online relationships.

  18. [School difficulties in adolescence].

    Science.gov (United States)

    Schwarzenberg, T L; Buffone, M R; Scardia, C; Facente, C

    2002-12-01

    Loss, failure and desertion are those words, which better describe the most frequent difficulties incurred by teenagers, and their relation to the school environment, and indicate, as well, the lack of connection between individual aspirations and school achievements obtained. Despite the likelihood of school difficulties throughout the entire educational career, from the kindergarten to the college, we are able to recognize certain specific "disturbances" which come out during the adolescence, basically relating to the school experiences. School failure, school desertion and school abandonment are, in fact, issues mainly discussed in coincidence with the beginning of the adolescent age and the attending of the high school. The aetiopathogenesis of school discomfort is mostly determined by more than only one factor: psychological, physical, cognitive and environmental aspects, all together, contribute in various ways, to the rise and persisting of the above described problems. Suggesting a univocal characterization of the adolescent with school difficulties, is indeed a hard task, since school failure is not an exclusive feature of only one kind of personality or the expression of only one type of conflict. Once identified the individuals more subject to risk, and the warning signs of actual uneasiness, it is important therefore to intervene timely and in different ways in order to avoid the worsening or the excessive extension of the school difficulties and of their frequent and serious consequences on the teenagers' individual and domestic well-being. Such type of prevention definitely belongs to the Adolescent Medicine, and must be developed on different levels, by involving not only the teenagers, but also their families, the school, and the whole social environment in which the teenagers live and with which they interact.

  19. Eating disorders in adolescence

    OpenAIRE

    JÁGLOVÁ, Štěpánka

    2013-01-01

    The bachelor degree work deals with disorders food intake, in particular, mental anorexia and mental bulimia in maturing period. The theoretical part is aimed at maturing problems and food intake disorders generally. There is characteristics and division of maturing period into early and late adolescence including psychological and physical changes which are typical for this period. Then food intake disorders, their causes, effects and their possible treatment are specified. The aim of the pr...

  20. The adolescent towards knowledge

    OpenAIRE

    Compagnucci, Elsa Rosa; Cardós, Paula Daniela; Denegri, Adriana; Barboza, Cecilia

    2002-01-01

    The following article deals with knowledge, relationships, representations and values that pupils together with teachers perform daily at school. It includes our research project called “Adolescence and School” which has been implemented since 1995 in our Institution, subject called “Psychological Foundation on education”. Throughout its development, we have tried to get to know about in what positions teachers and students are towards knowledge. Our purpose is to make a critic- ref...

  1. The adolescent towards knowledge

    OpenAIRE

    Compagnucci, Elsa Rosa; Cardós, Paula Daniela

    2003-01-01

    The following article deals with knowledge, relationships, representations and values that pupils together with teachers perform daily at school. It includes our research project called "Adolescence and School" which has been implemented since 1995 in our Institution, subject called "Psychological Foundation on education". Throughout its development, we have tried to get to know about in what positions teachers and students are towards knowledge. Our purpose is to make a critic- reflexive per...

  2. Patterns of Parenting during Adolescence: Perceptions of Adolescents and Parents.

    Science.gov (United States)

    Paulson, Sharon E.; Sputa, Cheryl L.

    1996-01-01

    Explores differences in maternal and paternal parenting styles and involvement, the differences between parents' and adolescents' perceptions of parenting style and involvement, and changes in parenting style and involvement between the adolescents' 9th and 12th grade years. Subjects were 244 ninth graders from the Southeast and Midwest. Discusses…

  3. Adolescent and Parent Perceptions of Media Influence on Adolescent Sexuality

    Science.gov (United States)

    Werner-Wilson, Ronald Jay; Fitzharris, Jennifer Lynn; Morrissey, Kathleen M.

    2004-01-01

    Empirical evidence suggests that television and other media influence adolescents' attitudes and behaviors. Much of the research in this area is based on surveys in which adolescents are asked to rank the relative importance of a fixed set of factors such as parents, peers, and media. We reviewed data from focus groups conducted with adolescents…

  4. Patterns of Parenting during Adolescence: Perceptions of Adolescents and Parents.

    Science.gov (United States)

    Paulson, Sharon E.; Sputa, Cheryl L.

    1996-01-01

    Explores differences in maternal and paternal parenting styles and involvement, the differences between parents' and adolescents' perceptions of parenting style and involvement, and changes in parenting style and involvement between the adolescents' 9th and 12th grade years. Subjects were 244 ninth graders from the Southeast and Midwest. Discusses…

  5. Adolescents: Pour une methodologie specifique (Adolescents: Toward a Specific Methodology).

    Science.gov (United States)

    Capelle, Guy

    1994-01-01

    It is argued that, if educators want French to regain and retain its appeal as a second language for young adults, they must make good use of the available resources, including international exchange opportunities, to target adolescent students. This would include refining instructional objectives to reflect adolescent concerns and needs. (MSE)

  6. Parental Divorce, Adolescents' Feelings toward Parents and Drunkenness in Adolescents

    NARCIS (Netherlands)

    Tomcikova, Zuzana; Geckova, Andrea Madarasova; Reijneveld, Sijmen A.; van Dijk, Jitse P.

    2011-01-01

    The aim of this study was to explore the association between parental divorce and adolescent drunkenness and the contribution of adolescents' feelings toward their parents to this association. Cross-sectional data on 3,694 elementary school students from several cities in Slovakia (mean age 14.3, 49

  7. Adolescent and Parent Perceptions of Media Influence on Adolescent Sexuality

    Science.gov (United States)

    Werner-Wilson, Ronald Jay; Fitzharris, Jennifer Lynn; Morrissey, Kathleen M.

    2004-01-01

    Empirical evidence suggests that television and other media influence adolescents' attitudes and behaviors. Much of the research in this area is based on surveys in which adolescents are asked to rank the relative importance of a fixed set of factors such as parents, peers, and media. We reviewed data from focus groups conducted with adolescents…

  8. Socioeconomic and Marital Outcomes of Adolescent Marriage, Adolescent Childbirth, and Their Co-Occurrence.

    Science.gov (United States)

    Teti, Douglas M.; Lamb, Michael E.

    1989-01-01

    Examined adolescent marriage, adolescent childbirth, and their co-occurrence in adult women. Poorest socioeconomic outcomes were associated with adolescent childbirth regardless of presence or timing of first marriage. Marital instability was associated with both adolescent marriage and adolescent childbirth. Findings suggest that risk associated…

  9. Emotional variability during mother-adolescent conflict interactions: Longitudinal links to adolescent disclosure and maternal control

    NARCIS (Netherlands)

    Van der Giessen, D.; Branje, S.; Keijsers, L.; Van Lier, P.A.C.; Koot, H.M.; Meeus, W.

    2014-01-01

    The aim of this study was to examine relations of emotional variability during mother-adolescent conflict interactions in early adolescence with adolescent disclosure and maternal control in early and late adolescence. Data were used from 92 mother-adolescent dyads (M age T1 = 13.05; 65.20% boys) th

  10. Adolescent Sexuality and Parent-Adolescent Processes: Promoting Healthy Teen Choices.

    Science.gov (United States)

    Meschke, Laurie L.; Bartholomae, Suzanne; Zentall, Shannon R.

    2000-01-01

    Reports on trends in adolescent sexual health, the relation between parenting and adolescent sexual outcomes, and adolescent sexuality interventions. Discusses parenting efforts related to adolescent sexual behavior. Examines adolescent sexuality programs with a parent component. Review of 19 programs supports the incorporation of theory and the…

  11. Overweight and constipation in adolescents

    Directory of Open Access Journals (Sweden)

    Morais Mauro B

    2011-04-01

    Full Text Available Abstract Background The association between overweight and gastrointestinal symptoms has been recently studied in the literature; however, few studies have evaluated the association between overweight and constipation in adolescents in a community-based sample. The aim of this study was to analyze the prevalence of constipation and its association with being overweight in a community-based survey with adolescents. Methods This cross-sectional study included 1,077 adolescents who were enrolled in five schools in the city of Sao José dos Campos, Brazil. Constipation was defined according to modified and combined Rome III criteria for adolescents and adults. Being overweight was defined as a body mass index (BMI that was equal to or greater than that of the 85th percentile for age and gender. Results Constipation was diagnosed in 18.2% (196/1077 of the included adolescents. There was no significant difference in the prevalence of constipation in males and females who were both younger and older than 14 years. Fecal incontinence was observed in 25 adolescents, 22 (88.0% of whom were diagnosed as being constipated. The prevalence of being overweight was found in 13.5% (145/1077 of the study population. The prevalence of constipation was observed to be similar in adolescents who were (19.4%; 28/144 and were not (18.0%; 168/933 overweight (p = 0.764; OR = 1.10. Fecal incontinence that was associated with constipation was more frequent in adolescents who were overweight (37.0%; 8/28 than in adolescents who were not overweight (8.5%; 14/168; p = 0.005; OR = 4.40. Conclusions The prevalence of constipation was high among the investigated adolescents. There was no association between being overweight and constipation; however, an association between being overweight and fecal incontinence in constipated adolescents was confirmed.

  12. [Adolescent contraception. Current trends].

    Science.gov (United States)

    Anthuber, Sabine

    2005-10-01

    Despite easy availability of contraception, Germany is confronted with the problem of increasing rates of pregnancies and abortions in minors. Prescription of contraceptives that do not rely on compliance and are acceptable to adolescents is required in addition to improved counseling. For that purpose, adherence to the guidelines for the use of contraceptives in minors written by the consortium for legislation in medicine (AG Medizinrecht) is essential. Oral contraceptives are the most commonly prescribed form of birth control, advantages include reversibility as well as a good tolerance and safety profile. New developments are low-dose compounds, novel progestins, prevention of ovulation by pure gestagen pills and the long-term use of low-dose monophasic micro pills. Long-term contraceptives like subdermally implantable depot compounds or hormone-releasing pessaries in utero have been used on a regular basis and seem a convenient alternative for birth control for longer periods, also in adolescents. The easy-to-use intravaginal ring and the birth control patch have expanded the spectrum of hormone-releasing contraceptive systems. Studies show improved compliance and a possible reduction of unintentional pregnancies due to application errors. Amelioration of the range of highly effective birth control products different modes of application will hopefully lead to drop in the rate of unplanned pregnancies, especially in adolescents.

  13. Hypermobility in Adolescent Athletes

    DEFF Research Database (Denmark)

    Schmidt, Heidi; Pedersen, Trine Lykke; Junge, Tina

    2017-01-01

    athletes, and to study the association of GJH with pain, function, HRQoL, and musculoskeletal injuries. Methods A total of 132 elite-level adolescent athletes (36 adolescent boys, 96 adolescent girls; mean ± SD age, 14.0 ± 0.9 years), including ballet dancers (n = 22), TeamGym gymnasts (n = 57), and team......-reported questionnaires, and part of physical performance was assessed by 4 postural-sway tests and 2 single-legged hop-for-distance tests. Results Overall prevalence rates for GJH4, GJH5, and GJH6 were 27.3%, 15.9%, and 6.8%, respectively, with a higher prevalence of GJH4 in ballet dancers (68.2%) and TeamGym gymnasts...... significantly larger center-of-pressure path length across sway tests. Conclusion For ballet dancers and TeamGym gymnasts, the prevalence of GJH4 was higher than that of team handball players. For ballet dancers, the prevalence of GJH5 and GJH6 was higher than that of team handball players and the general...

  14. Adolescent Girls and Abortion.

    Science.gov (United States)

    Wellisch, Lawren; Chor, Julie

    2015-09-01

    Abortion is an extremely common procedure in the United States, with approximately 2% of women having an abortion before age 19 years. Although most pediatricians do not provide abortions, many will care for a young woman who is either considering an abortion or has already had one; therefore, the pediatrician should be able to provide accurate and appropriate counseling about this option. To provide the best care for adolescent patients considering abortion, pediatricians must be knowledgeable of aspects of abortion that are universal to all women and have an understanding of considerations specific to the adolescent patient. The purpose of this article is to (1) review recent statistics about teenagers and abortion, (2) explain the different types of abortion available to teenagers who desire to terminate an unwanted pregnancy, (3) discuss aspects of abortion unique to the adolescent population, such as insurance coverage and parental involvement laws, and (4) address common misconceptions about abortion. [Pediatr Ann. 2015;44(9):384-385,388,390,392.]. Copyright 2015, SLACK Incorporated.

  15. Media multitasking in adolescence.

    Science.gov (United States)

    Cain, Matthew S; Leonard, Julia A; Gabrieli, John D E; Finn, Amy S

    2016-12-01

    Media use has been on the rise in adolescents overall, and in particular, the amount of media multitasking-multiple media consumed simultaneously, such as having a text message conversation while watching TV-has been increasing. In adults, heavy media multitasking has been linked with poorer performance on a number of laboratory measures of cognition, but no relationship has yet been established between media-multitasking behavior and real-world outcomes. Examining individual differences across a group of adolescents, we found that more frequent media multitasking in daily life was associated with poorer performance on statewide standardized achievement tests of math and English in the classroom, poorer performance on behavioral measures of executive function (working memory capacity) in the laboratory, and traits of greater impulsivity and lesser growth mindset. Greater media multitasking had a relatively circumscribed set of associations, and was not related to behavioral measures of cognitive processing speed, implicit learning, or manual dexterity, or to traits of grit and conscientiousness. Thus, individual differences in adolescent media multitasking were related to specific differences in executive function and in performance on real-world academic achievement measures: More media multitasking was associated with poorer executive function ability, worse academic achievement, and a reduced growth mindset.

  16. HPV Infections in Adolescents

    Directory of Open Access Journals (Sweden)

    Anna-Barbara Moscicki

    2007-01-01

    Full Text Available Adolescents who are sexually active have the highest rates of prevalent and incident HPV infection rates with over 50–80% having infections within 2–3 years of initiating intercourse. These high rates reflect sexual behavior and biologic vulnerability. Most infections are transient in nature and cause no cytologic abnormality. However, a small number of adolescents will not clear the infection. Persistence of HPV is strongly linked to the development of high-grade squamous intra-epithelial lesions (HSIL and invasive cancer. The HSIL detected, however, does not appear to progress rapidly to invasive cancer. Understanding the natural history of HPV in adolescents has shed light into optional treatment strategies which include watchful observation of atypical squamous cells of undetermined significance (ASCUS and low grade (LSIL. The association between age of first intercourse and invasive cancer cannot be ignored. Consequently, initiating screening at appropriate times in this vulnerable group is essential. In addition, with the advent of the HPV vaccine, vaccination prior to the onset of sexual activity is critical since most infections occur within a short time frame post initiation.

  17. Chinese American adolescents: perceived parenting styles and adolescents' psychosocial health.

    Science.gov (United States)

    Yuwen, W; Chen, A C C

    2013-06-01

    Asian Americans are one of the fastest-growing minority groups in the USA, and Chinese constitute the largest group. Evidence suggests that Asian American adolescents experience higher levels of depressive symptoms than their same-gender white counterparts. Quantitative findings suggest associations between parenting factors and Chinese American adolescents' mental health. A qualitative understanding regarding Chinese American adolescents' perceived parenting styles and its relationship with adolescents' psychosocial health is warranted. To gain an in-depth understanding of Chinese American adolescents' perceived parenting styles and how parenting styles might influence adolescents' psychosocial health. In this qualitative study, we recruited 15 Chinese American adolescents aged 12-17 years in a southwest metropolitan area. We conducted two focus group interviews. Participants also filled out a brief questionnaire that included their socio-demographic information, immigration history and level of acculturation. Participants reported perceiving that parents had high expectations about academic performance and moral values. They also perceived stricter family rules regarding choices of friends compared with their non-Asian peers. Parents tended to be more protective of girls than of boys. Both Chinese American boys and girls reported poor or ineffective communication with their parents, which contributed to increased conflict between parents and adolescents and emotional distress of the adolescents. The findings provide evidence for nurses to develop linguistically and culturally tailored resources (e.g. parent support groups, programs aimed to improving parent-child communication) or connect these families with existing resources to enhance parenting skills and consequently reduce emotional distress of their adolescent children. © 2012 The Authors. International Nursing Review © 2012 International Council of Nurses.

  18. Family Characteristics and Adolescent Substance Use.

    Science.gov (United States)

    Stephenson, Andy L.; And Others

    1996-01-01

    Study used self-report questionnaire data from high school students to determine the relation between adolescents' perception of family characteristics and adolescent substance use patterns. Results indicate adolescents' perception of maternal substance use, family hardiness, and age of the adolescent were significant predictors of substance use.…

  19. Risky traffic behaviour among young adolescents.

    NARCIS (Netherlands)

    2012-01-01

    Adolescence is the period between childhood and adulthood. Compared with older adolescents (18-24 years old), young adolescents (10-17 years old) exhibit more risky behaviour. Because of their physical and mental development, young adolescents are attracted to risky challenges, they are more

  20. Risky traffic behaviour among young adolescents.

    NARCIS (Netherlands)

    2012-01-01

    Adolescence is the period between childhood and adulthood. Compared with older adolescents (18-24 years old), young adolescents (10-17 years old) exhibit more risky behaviour. Because of their physical and mental development, young adolescents are attracted to risky challenges, they are more suscep

  1. Adolescent Motherhood and Postpartum Depression

    Science.gov (United States)

    Birkeland, Robyn; Thompson, J. Kevin; Phares, Vicky

    2005-01-01

    Adolescent mothers undergo unique personal and social challenges that may contribute to postpartum functioning. In this exploratory investigation completed within a risk and resilience framework, 149 adolescent mothers, ages 15 to 19, who participated in school-based teen parents' programs, completed measures of parental stress (social isolation…

  2. Literacy Perceptions of Runaway Adolescents.

    Science.gov (United States)

    Blair-Larsen, Susan M.

    A study investigated the literacy needs of adolescents staying in short-term crisis intervention centers--shelters for teens who have run away or are otherwise homeless. During a 6-month period, interviews were conducted in a non-threatening, informal environment; the adolescents responded to open-ended questions about their histories of reading…

  3. Discrimination against Muslim American Adolescents

    Science.gov (United States)

    Aroian, Karen J.

    2012-01-01

    Although there is ample evidence of discrimination toward Muslim Americans in general, there is limited information specific to Muslim American adolescents. The few existing studies specific to this age group suggest that Muslim American adolescents encounter much discrimination from teachers, school administrators, and classmates. This…

  4. Stress Literacy in Australian Adolescents

    Science.gov (United States)

    Varlow, Megan; Wuthrich, Viviana; Murrihy, Rachael; Remond, Louise; Tuqiri, Rebekka; van Kessel, Jacobine; Wheatley, Anna; Dedousis-Wallace, Anna; Kidman, Antony

    2009-01-01

    Stress literacy is a term that refers to knowledge about stress and stress management techniques. Levels of stress literacy were examined in more than nine hundred Australian adolescents by providing a short stress-management education session and assessing stress literacy using a pre-post survey design. It was found that while adolescents had a…

  5. Correlates of Adolescent Life Satisfaction.

    Science.gov (United States)

    Feldman, Mary Jane; Gaier, Eugene L.

    1980-01-01

    Substantial differences among late adolescents who possessed different levels of satisfaction with life showed up in relation to leisure time enjoyment, religious involvement, health, friendships, and personal efficacy. Almost one-third of the sample studied had not come through their adolescences feeling good about their lives. (Author/GC)

  6. Adolescent Brain Development and Drugs

    Science.gov (United States)

    Winters, Ken C.; Arria, Amelia

    2011-01-01

    Research now suggests that the human brain is still maturing during adolescence. The developing brain may help explain why adolescents sometimes make decisions that are risky and can lead to safety or health concerns, including unique vulnerabilities to drug abuse. This article explores how this new science may be put to use in our prevention and…

  7. Parenting and Adolescents' Sexual Initiation

    Science.gov (United States)

    Longmore, Monica A.; Eng, Abbey L.; Giordano, Peggy C.; Manning, Wendy D.

    2009-01-01

    This study draws on social control and social learning theories to examine the role of dating-specific attitudes and practices as predictors of adolescents' sexual initiation. We include attention to the adolescent's reaction to control attempts as a further means of assessing family dynamics (i.e., frequency of dating disagreements). The study…

  8. Best Practices for Adolescent ELLs

    Science.gov (United States)

    Rance-Roney, Judith

    2009-01-01

    Adolescent English language learners present particular challenges for schools. The population of adolescent ELLs is diverse, and their educational needs are affected by differences in immigration status, quality of educational background, native language, cultural distance from U.S. culture, future plans, and economic status. The article offers…

  9. Parents of "Beyond Control" Adolescents

    Science.gov (United States)

    Robinson, Paul A.

    1978-01-01

    Examines the child rearing and disciplinary methods of parents of adolescent boys who were reported by their parents to be serious control problems. On the basis of a social learning analysis of family relationships, it was hypothesized that parental difficulty in controlling adolescents was related to two factors: parent consistency in setting…

  10. Contraception and the Adolescent Diabetic.

    Science.gov (United States)

    Fennoy, Ilene

    1989-01-01

    Data from a study of 11 teenage diabetics suggests that pregnancy among adolescent diabetics is more frequent than among the general population, at a time when diabetic control is poor because of psychosocial factors associated with adolescence. Current recommendations regarding contraception for diabetic women, focusing on barrier methods, are…

  11. Cluster Analysis of Adolescent Blogs

    Science.gov (United States)

    Liu, Eric Zhi-Feng; Lin, Chun-Hung; Chen, Feng-Yi; Peng, Ping-Chuan

    2012-01-01

    Emerging web applications and networking systems such as blogs have become popular, and they offer unique opportunities and environments for learners, especially for adolescent learners. This study attempts to explore the writing styles and genres used by adolescents in their blogs by employing content, factor, and cluster analyses. Factor…

  12. Single Parenting of the Adolescent.

    Science.gov (United States)

    Carroll

    1991-06-01

    This article discusses issues that are of interest and concern to all parents of adolescents, but that may be particularly difficult for single parents to manage. It also provides a framework for examining the areas of similarity as well as difference between the adolescent and the single parent. Attention is paid to the potential advantages of single-parent status.

  13. Stress Literacy in Australian Adolescents

    Science.gov (United States)

    Varlow, Megan; Wuthrich, Viviana; Murrihy, Rachael; Remond, Louise; Tuqiri, Rebekka; van Kessel, Jacobine; Wheatley, Anna; Dedousis-Wallace, Anna; Kidman, Antony

    2009-01-01

    Stress literacy is a term that refers to knowledge about stress and stress management techniques. Levels of stress literacy were examined in more than nine hundred Australian adolescents by providing a short stress-management education session and assessing stress literacy using a pre-post survey design. It was found that while adolescents had a…

  14. Noise Exposures of Rural Adolescents

    Science.gov (United States)

    Humann, Michael; Sanderson, Wayne; Flamme, Greg; Kelly, Kevin M.; Moore, Genna; Stromquist, Ann; Merchant, James A.

    2011-01-01

    Purpose: This project was conducted to characterize the noise exposure of adolescents living in rural and agricultural environments. Methods: From May to October, 25 adolescents ages 13 through 17, living either on a farm or a rural nonfarm, were enrolled in the study. Subjects received training on the correct operation and use of personal noise…

  15. Ego and Leadership among Adolescents

    Science.gov (United States)

    Thangarajathi, S.

    2010-01-01

    The period of adolescence is designated as the period of storm and stress and age of revolt. This is considered as being one of the most difficult stage in the life of any individual. Thus adolescence is the most critical stage with a distinct phase of rapid physical, psychological and social behavioral changes and emotional disturbances. As Ego…

  16. Narcissism--An Adolescent Disorder?

    Science.gov (United States)

    Waddell, Margot

    2006-01-01

    This paper argues that the adolescent process needs to be accorded its own particularity of reference, especially where narcissism is concerned. The paper draws on literary and clinical examples to describe what is termed the "adolescent organisation". In many ways, this organisation reflects post-Kleinian theory of what constitutes narcissistic…

  17. Best Practices for Adolescent ELLs

    Science.gov (United States)

    Rance-Roney, Judith

    2009-01-01

    Adolescent English language learners present particular challenges for schools. The population of adolescent ELLs is diverse, and their educational needs are affected by differences in immigration status, quality of educational background, native language, cultural distance from U.S. culture, future plans, and economic status. The article offers…

  18. Discrimination against Muslim American Adolescents

    Science.gov (United States)

    Aroian, Karen J.

    2012-01-01

    Although there is ample evidence of discrimination toward Muslim Americans in general, there is limited information specific to Muslim American adolescents. The few existing studies specific to this age group suggest that Muslim American adolescents encounter much discrimination from teachers, school administrators, and classmates. This…

  19. The prodromal phase of obesity-related chronic kidney disease: early alterations in cardiovascular and renal function in obese children and adolescents.

    Science.gov (United States)

    Doyon, Anke; Schaefer, Franz

    2013-11-01

    Childhood overweight and obesity is a relevant health condition with multi-organ involvement. Obesity shows significant tracking into adult life and is associated with an increased risk of serious adverse health outcomes both during childhood and later adulthood. The classical sequelae of obesity such as hypertension, metabolic syndrome and inflammation do develop at a paediatric age. Cardiovascular consequences, such as increased carotid intima-media thickness, and left ventricular hypertrophy, as well as functional alterations of the heart and arteries, are commonly traceable at an early age. Renal involvement can occur at a young age and is associated with a high probability of progressive chronic kidney disease. There is solid evidence suggesting that consequent treatment including both lifestyle changes and pharmacological therapy can reduce cardiovascular, metabolic and renal risks in obese children and adolescents.

  20. Obesity and nutrition in adolescents.

    Science.gov (United States)

    Steinbeck, Kate

    2009-12-01

    Adolescence is a period of life that encompasses rapid physical growth and dramatic psychosocial change. Over the centuries, humans have evolved an energy balance system that is biased toward fat storage. Obesity has become the most prevalent nutritional concern in adolescents, and clearly it has a complex etiology that includes both genetic and lifestyle aspects. The greatest impact of overweight and obesity in adolescents is the appearance of related physical and psychosocial comorbidity and the tracking of these into adulthood. Thus, there is a strong imperative to treat adolescent overweight and obesity before lifestyles become entrenched and significant comorbidity intervenes. Anorexia nervosa, at the opposite end of the weight spectrum, exhibits many older evolutionary traits that attempt to protect against undernutrition. Iron and vitamin D deficiencies are common in adolescents, both of which have important nutritional aspects.

  1. Diagnosis of depression among adolescents

    DEFF Research Database (Denmark)

    Haavet, Ole Rikard; Christensen, Kaj Aage Sparle; Sirpal, Manjit

    2007-01-01

    BACKGROUND: The objective of the study is to improve general practitioners' diagnoses of adolescent depression. Major depression is ranked fourth in the worldwide disability impact. METHOD: Validation of 1) three key questions, 2) SCL-dep6, 3) SCL-10, 4) 9 other SCL questions and 5) WHO-5....... A number of GPs will be recruited from both countries and at least 162 adolescents will be enrolled in the study from the patient lists of the GPs in each country, giving a total of at least 323 adolescent participants. DISCUSSION: The proportion of adolescents suffering from depressive disorders also...... seems to be increasing worldwide. Early interventions are known to reduce this illness. The earlier depression can be identified in adolescents, the greater the advantage. Therefore, we hope to find a suitable questionnaire that could be recommended for GPs....

  2. Adolescents' lived experience of epilepsy.

    Science.gov (United States)

    Eklund, Pernilla Garmy; Sivberg, Bengt

    2003-02-01

    To improve the well-being of adolescents with epilepsy, research is needed on how adolescents cope. In this study, Lazarus' model of stress and coping and Antonovsky's Theory of Sense of Coherence were used as the theoretical framework. The aim was to describe the lived experience of adolescents with epilepsy and their coping skills. The participants were 13-19 years old with an epilepsy diagnosis but without mental retardation or cerebral palsy. The study was performed in southern Sweden at the pediatric department of a university hospital. Semistructured and open-ended interviews were conducted with 13 adolescents. The transcripts were analyzed with manifest and latent content analysis. All the adolescents had developed strategies to cope with the emotional strains caused by epilepsy. They experienced strains from the seizures, limitation of leisure activities, side effects of medication, and feelings of being different. The coping strategies described were finding support, being in control, and experimenting.

  3. Peer influence on adolescent snacking

    DEFF Research Database (Denmark)

    Nørgaard, Maria Kümpel; Hansen, Kathrine Nørgaard; Grunert, Klaus G

    2013-01-01

    show that the youngest adolescents and the girls perceived the highest influence from peers, and that peer social influence has more effect on what adolescents perceive as important snack attributes as compared to more personal factors. The focus group results show that adolescents purchase and consume......Purpose – The purpose of the research presented in this paper is 1) To explore peer influence and the social and symbolic meaning that adolescents (10 to 16 years) attach to snacks; and 2) to investigate the relative influence of peer influence compared to personal factors in explaining perceived...... importance of snack attributes; and 3) To investigate age and gender differences in the peer influence process. Design/methodology/approach – A web-based survey distributed via email was combined with follow-up focus groups including adolescents aged 10 to 16 years in Denmark. Findings – The survey results...

  4. Diagnosis of depression among adolescents

    DEFF Research Database (Denmark)

    Haavet, Ole Rikard; Christensen, Kaj Aage Sparle; Sirpal, Manjit

    2007-01-01

    BACKGROUND: The objective of the study is to improve general practitioners' diagnoses of adolescent depression. Major depression is ranked fourth in the worldwide disability impact. METHOD: Validation of 1) three key questions, 2) SCL-dep6, 3) SCL-10, 4) 9 other SCL questions and 5) WHO-5...... in a clinical study among adolescents. The Composite International Diagnostic Interview (CIDI) is to be used as the gold standard interview. The project is a GP multicenter study to be conducted in both Norway and Denmark. Inclusion criteria are age (14-16) and fluency in the Norwegian and Danish language....... A number of GPs will be recruited from both countries and at least 162 adolescents will be enrolled in the study from the patient lists of the GPs in each country, giving a total of at least 323 adolescent participants. DISCUSSION: The proportion of adolescents suffering from depressive disorders also...

  5. Obesity in childhood and adolescence: clinical diagnosis and management.

    Science.gov (United States)

    Kiess, W; Reich, A; Müller, G; Galler, A; Kapellen, T; Raile, K; Böttner, A; Seidel, B; Kratzsch, J

    2001-01-01

    The industrialized countries around the world are experiencing an epidemic of childhood obesity. The level of fatness of a child at which morbidity increases acutely and/or later in life is determined on an individual basis. Overall, however, childhood obesity substantially increases the risk of subsequent morbidity whether or not obesity persists into adulthood. The genetic basis of childhood obesity has been elucidated to some extent through the discovery of leptin, the ob gene product, and the increasing knowledge of the role of neuropeptides such as pro-opiomelanocortin, neuropeptide Y and the melanocyte-concentrating hormone receptors. Environmental and exogenous factors are the main contributors to the development of a high degree of body fatness early in life. Studies involving twins suggest that approximately 50% of the tendency toward obesity is inherited. There are numerous disorders, including a number of endocrine disorders, such as Cushing's syndrome and hypothyroidism, and genetic syndromes, such as Prader-Labhard-Willi syndrome and Bardet-Biedl syndrome, that can present with obesity. A simple diagnostic algorithm allows for differentiation between primary and secondary obesity. Among the most common sequelae of primary childhood obesity are hypertension, dyslipidemia, back pain and psychosocial problems. It is somewhat ironic that the definition of obesity in childhood is not an easy one. Direct measurements of body fat content, such as hydrodensitometry, bioimpedance, or dual-energy X-ray absorptiometry, are useful tools in scientific studies. Body mass index (BMI) is, however, now generally accepted to be a good clinical measure for the definition of obesity in children and adolescents. In preadolescent boys, BMI also relates to muscle mass and should be used for the definition of fat mass with great caution. An increased risk of death from cardiovascular disease in adults has been found in patients whose BMI had been greater than the 75th

  6. Maturation of the adolescent brain

    Directory of Open Access Journals (Sweden)

    Arain M

    2013-04-01

    Full Text Available Mariam Arain, Maliha Haque, Lina Johal, Puja Mathur, Wynand Nel, Afsha Rais, Ranbir Sandhu, Sushil Sharma Saint James School of Medicine, Kralendijk, Bonaire, The Netherlands Abstract: Adolescence is the developmental epoch during which children become adults – intellectually, physically, hormonally, and socially. Adolescence is a tumultuous time, full of changes and transformations. The pubertal transition to adulthood involves both gonadal and behavioral maturation. Magnetic resonance imaging studies have discovered that myelinogenesis, required for proper insulation and efficient neurocybernetics, continues from childhood and the brain's region-specific neurocircuitry remains structurally and functionally vulnerable to impulsive sex, food, and sleep habits. The maturation of the adolescent brain is also influenced by heredity, environment, and sex hormones (estrogen, progesterone, and testosterone, which play a crucial role in myelination. Furthermore, glutamatergic neurotransmission predominates, whereas gamma-aminobutyric acid neurotransmission remains under construction, and this might be responsible for immature and impulsive behavior and neurobehavioral excitement during adolescent life. The adolescent population is highly vulnerable to driving under the influence of alcohol and social maladjustments due to an immature limbic system and prefrontal cortex. Synaptic plasticity and the release of neurotransmitters may also be influenced by environmental neurotoxins and drugs of abuse including cigarettes, caffeine, and alcohol during adolescence. Adolescents may become involved with offensive crimes, irresponsible behavior, unprotected sex, juvenile courts, or even prison. According to a report by the Centers for Disease Control and Prevention, the major cause of death among the teenage population is due to injury and violence related to sex and substance abuse. Prenatal neglect, cigarette smoking, and alcohol consumption may also

  7. Parent-Adolescent Discrepancies Regarding Adolescents' Peer-Related Loneliness: Associations with Adolescent Adjustment.

    Science.gov (United States)

    Spithoven, Annette W M; Vanhalst, Janne; Lodder, Gerine; Bijttebier, Patricia; Goossens, Luc

    2017-03-27

    Because loneliness is a subjective experience, it is often examined using self-reports. Yet, researchers have started to use other-reports to examine loneliness. As previous research suggests that discrepancies between self- and other views might have important implications for adolescents' mental health, the current study examines discrepancies in multi-informant reports on adolescents' loneliness in relation with prosocial behavior, aggression, and adolescents' parent-related loneliness. The sample consisted of 374 mother-adolescent dyads and 318 father-adolescent dyads (41.80% male, M age  = 15.67 years, SD = 1.25). Results indicated that informants used different reference points to assess adolescents' peer-related loneliness, but were otherwise comparable. Moreover, informant discrepancies were associated with greater adolescents' reported parent-related loneliness. The current study did not provide evidence that discrepancies were related to prosocial or aggressive behavior. The current study adds to the notion that other-reports on loneliness show substantial convergence with self-reports. In addition, this study indicates that the discrepancy between other- and self-reports on loneliness holds valuable information for adolescent socio-emotional adjustment.

  8. 脑震荡后脑功能障碍与相关因素回顾性研究%Rctrospectiv study on the concussion sequelas and correlative factors

    Institute of Scientific and Technical Information of China (English)

    肖兴义; 尹晓梅; 薛关生; 蔡宝仁; 王丽

    2001-01-01

    目的探讨脑震荡后脑功能障碍形成原因、类型和相关因素。方法对1995年3月~1999年10月治疗的86例脑震荡后脑功能障碍临床资料运行回顾性分析.结果 86例脑震荡后脑功能障碍占同期脑震荡的21.6%,通过经颅三维多普勒(3D-TCD)检测显示,尼莫地平组在解除脑震荡引起脑血管痉挛和改善脑血流平均峰速度明显优干治疗组。结论伤后是否残留脑功能障碍取决于颅脑损伤程度和由此广生的意识障碍时间与脑血液循环障碍,治疗时间与采取主要治疗方法等。%Objective To discuss the causes types and correlative factors of brain dysfunction after concussion. Method 86 cases with concussion sequela treated during the period of March 1995 to October 1999 were analyzed retrospectively. Result 86 patients with sequelas accounted for 21.6% of concussion patients in the same period. According to the results of three-dimensional trancranial doppler (3D-TCD)test. In Nimodipine group it was better to release cerebral vessel spasm cassed by concussion and improve the gverage peak velocity of cerebral blood flow, The results were better than other groups. Conclusion Wheather there would be sequelas after head injury depended on the injure degree, unconsciousness duration and cerebral blood circulation malfunction. The correlation factors included injured causes, unconsciousness duration, therapeutical duration and methods of treatment .

  9. 头针治疗周围性面瘫后遗症的疗效分析%Efficacy analysis of treating peripheral facial paralysis sequela by scalp acupuncture

    Institute of Scientific and Technical Information of China (English)

    李文革

    2014-01-01

    Objective:To research the clinical efficacy of scalp acupuncture on treating peripheral facial paralysis sequela. Methods:92 patients with peripheral facial paralysis were randomly divided into control group and treated group, 46 in each. The control group was treated by traditional acupuncture methods; treated group was given scalp acupuncture treatment. Results:The effect of the treated group was significantly better than the control group, in treated group the facial function recovery time and total treatment time was shorter than the control group, facial paralysis sequela recurrence rate in treated group was lower than that of control group. Conclusion:The clinical treatment effect of application of scalp acupuncture on treating peripheral facial paralysis sequela is very obvious.%目的:对应用头针技术对患有周围性面瘫后遗症的患者实施治疗的临床效果进行研究。方法:抽取92例患有周围性面瘫后遗症的患者,随机分为对照组和治疗组,平均每组46例。采用传统针灸方式对对照组患者实施治疗;采用头针技术对治疗组患者实施治疗。结果:治疗组患者周围性面瘫后遗症病情治疗效果明显优于对照组;面部功能复常时间和治疗总时间明显短于对照组;治疗组面瘫后遗症复发率明显低于对照组。结论:应用头针技术对患有周围性面瘫后遗症的患者实施治疗的临床效果非常明显。

  10. 醒脑开窍针法治疗卒中后抑郁症临床疗效%Clinical Effect of Acupuncture Combined with Chiropractic on Sequela of Apoplexy

    Institute of Scientific and Technical Information of China (English)

    贾军丽

    2015-01-01

    目的:分析醒脑开窍针法在中风后抑郁症的治疗中的应用效果。方法:2012年5月—2014年12月,我院共收治200例中风后抑郁症患者,按照随机的方式将其列入观察组与对照组,每组各为100例。两组均使用氟西汀进行临床治疗,在此基础上,观察组加用醒脑开窍针法。对比分析两组患者的治疗效果。结果:两组患者的治疗有效率和HAMD评分相比,观察组要显著优于对照组,比较差异有显著性的统计学的意义(P<0.05);两组患者均不存在明显的不良反应。结论:应用醒脑开窍针法对卒中后抑郁症进行治疗可以有效地提高治疗有效率,且不存在严重不良反应。%Objective: To observe the application and analyze the effect of acupuncture combined with chiropractic in the treatment of sequela of apoplexy. Methods: 200 cases with sequelae of stroke patients were selected randomly from our hospital and divided into two groups as an observation group and a control group,100 cases in each group. Patients in both groups were treated with acupuncture treatment, on the basis of this,patients in the observation group were given chiropractic treatment. The therapeutic effects of the two groups were compared. Results: After the treatment, the effective rate of the observation group (93%) was significantly better than that of the control group (75%), there was statistically significant difference (P<0.05) without adverse reactions in the patients in both groups during the treatment. Conclusion: The acupuncture combined with chiropractic has significant effect on sequela of apoplexy, which is, safe. So it is worthy of promotion.

  11. 中风后遗症患者家庭照顾者抑郁症患病状况分析%Analysis on Depression Incidence of Caregivers in Home for Apoplectic Sequela

    Institute of Scientific and Technical Information of China (English)

    张小红; 邓立军

    2011-01-01

    Objective:To analyse the mental status of caregivers in home for apoplexy sequela and the correlative factors in pathogenesis of depression(PSD).Methods:Assessed 92 caregivers in home for apoplexy sequela by Hamilton Depression Scale(HAMD),used SPSS 10.0 to calculate PSD incidence of caregivers in home with different sex,age,economic condition,educational level,and analysed their correlation.Results:The PSD incidence of caregivers in home is obviously higher than general people,P 0.01,and there is a significant difference.The PSD incidence has a significant correlation with sex,age and economic condition.Conclusion:It is necessary to take attention on mental status of caregivers in home for apoplexy sequela,and strengthen psychological persuasion for reducing the PSD incidence.%目的:分析中风后遗症患者家庭照顾者的心理状况及发生抑郁症(PSD)的相关因素.方法:采用汉密尔顿抑郁量表对92例中风后遗症患者家庭照顾者进行评估,采用SPSS10.0统计分析不同性别、年龄、经济状况、受教育程度的家庭照顾者PSD的发病率,分析其相关性.结果:中风后遗症患者家庭照顾者PSD发病率高于普通人群,P〈0.01,差异有统计学意义;性别、年龄、经济状况与PSD发病率均有显著相关性,P〈0.05.结论:应重视中风后遗症患者家庭照顾者的心理状况,加强心理疏导,降低PSD的发病率.

  12. Adolescent social isolation increases anxiety-like behavior and ethanol intake and impairs fear extinction in adulthood: Possible role of disrupted noradrenergic signaling.

    Science.gov (United States)

    Skelly, M J; Chappell, A E; Carter, E; Weiner, J L

    2015-10-01

    Alcohol use disorder, anxiety disorders, and post-traumatic stress disorder (PTSD) are highly comorbid, and exposure to chronic stress during adolescence may increase the incidence of these conditions in adulthood. Efforts to identify the common stress-related mechanisms driving these disorders have been hampered, in part, by a lack of reliable preclinical models that replicate their comorbid symptomatology. Prior work by us, and others, has shown that adolescent social isolation increases anxiety-like behaviors and voluntary ethanol consumption in adult male Long-Evans rats. Here we examined whether social isolation also produces deficiencies in extinction of conditioned fear, a hallmark symptom of PTSD. Additionally, as disrupted noradrenergic signaling may contribute to alcoholism, we examined the effect of anxiolytic medications that target noradrenergic signaling on ethanol intake following adolescent social isolation. Our results confirm and extend previous findings that adolescent social isolation increases anxiety-like behavior and enhances ethanol intake and preference in adulthood. Additionally, social isolation is associated with a significant deficit in the extinction of conditioned fear and a marked increase in the ability of noradrenergic therapeutics to decrease ethanol intake. These results suggest that adolescent social isolation not only leads to persistent increases in anxiety-like behaviors and ethanol consumption, but also disrupts fear extinction, and as such may be a useful preclinical model of stress-related psychopathology. Our data also suggest that disrupted noradrenergic signaling may contribute to escalated ethanol drinking following social isolation, thus further highlighting the potential utility of noradrenergic therapeutics in treating the deleterious behavioral sequelae associated with early life stress.

  13. Briquet's syndrome in adolescence.

    Science.gov (United States)

    Haberkern, R; Schmitt, R F; Taylor, C

    1985-08-01

    Briquet's syndrome, originally described more than 100 years ago, has recently become a subject of concern for physicians who work with adolescents. It is a chronic disorder that primarily affects women, is characterized by many symptoms involving a number of organ systems, and usually has a frustrating clinical course. It typically begins in the second or third decades, and only rarely subsides with time. Multiple diagnostic procedures, medications, and surgical operations are common, usually without evidence of significant disease. Complications can include substance abuse, depression, and suicide. Management centers upon viewing the symptoms as the patient's attempts to communicate difficulties in coping with stress.

  14. [Obesity, migration and adolescence].

    Science.gov (United States)

    Chamay-Weber, Catherine; Shehu-Brovina, Shqipe; Narring, Françoise

    2012-06-13

    Weight management interventions during adolescence are challenging. Migration adds complexity to this problem, making migrant families more vulnerable. Teenagers confront families to new values transmitted by the host society: opulence, junk food, video games. Obesity should not be seen as a single issue of calories-excess, but must be considered as being part of a larger problem, which takes into account the context of the familial and societal life of the migrants. The caregivers must have an overall view of the situation to provide appropriate approaches to weight management.

  15. [Feeding and adolescence].

    Science.gov (United States)

    Dain, E

    2012-09-01

    Adolescence is a transition period during which young people face many changes. Their desire to assert and differentiate themselves is reflected even in their food choices. These choices may have impacts until their adult lives. Moreover the media affect them in contradictory ways from images of extreme thinnesses to enticing advertisements of calorie food. A lack of self-esteem may appear, and in case of fertile ground may cause either diet, either addiction, or eating disorder. A comforting family as well as empathetic physicians have a main role in the medical care.

  16. Adolescent alcohol exposure: Are there separable vulnerable periods within adolescence?

    Science.gov (United States)

    Spear, Linda Patia

    2015-09-01

    There are two key alcohol use patterns among human adolescents that confer increased vulnerability for later alcohol abuse/dependence, along with neurocognitive alterations: (a) early initiation of use during adolescence, and (b) high rates of binge drinking that are particularly prevalent late in adolescence. The central thesis of this review is that lasting neurobehavioral outcomes of these two adolescent exposure patterns may differ. Although it is difficult to disentangle consequences of early use from later binge drinking in human studies given the substantial overlap between groups, these two types of problematic adolescent use are differentially heritable and hence separable to some extent. Although few studies using animal models have manipulated alcohol exposure age, those studies that have have typically observed timing-specific exposure effects, with more marked (or at least different patterns of) lasting consequences evident after exposures during early-mid adolescence than late-adolescence/emerging adulthood, and effects often restricted to male rats in those few instances where sex differences have been explored. As one example, adult male rats exposed to ethanol during early-mid adolescence (postnatal days [P] 25-45) were found to be socially anxious and to retain adolescent-typical ethanol-induced social facilitation into adulthood, effects that were not evident after exposure during late-adolescence/emerging adulthood (P45-65); exposure at the later interval, however, induced lasting tolerance to ethanol's social inhibitory effects that was not evident after exposure early in adolescence. Females, in contrast, were little influenced by ethanol exposure at either interval. Exposure timing effects have likewise been reported following social isolation as well as after repeated exposure to other drugs such as nicotine (and cannabinoids), with effects often, although not always, more pronounced in males where studied. Consistent with these timing

  17. Parental employment status and adolescents' health: the role of financial situation, parent-adolescent relationship and adolescents' resilience.

    Science.gov (United States)

    Bacikova-Sleskova, Maria; Benka, Jozef; Orosova, Olga

    2015-01-01

    The paper deals with parental employment status and its relationship to adolescents' self-reported health. It studies the role of the financial situation, parent-adolescent relationship and adolescent resilience in the relationship between parental employment status and adolescents' self-rated health, vitality and mental health. Multiple regression analyses were used to analyse questionnaire data obtained from 2799 adolescents (mean age 14.3) in 2006. The results show a negative association of the father's, but not mother's unemployment or non-employment with adolescents' health. Regression analyses showed that neither financial strain nor a poor parent-adolescent relationship or a low score in resilience accounted for the relationship between the father's unemployment or non-employment and poorer adolescent health. Furthermore, resilience did not work as a buffer against the negative impact of fathers' unemployment on adolescents' health.

  18. Adolescent health in South America.

    Science.gov (United States)

    Gaete, Veronica

    2016-08-01

    Since the 1950s, a significant amount of work has been done on behalf of the comprehensive health of young people in South America. This article focuses on the regional process of training health professionals to work with this age group. There are countries in which the growth of adolescent health training has been significant, others that have made progress but still have a narrower offer of teaching activities, and a few where only very basic and limited training is available. Latin American professional associations, scientific societies, and international organizations have also contributed to the education of the adolescent health work force. Although the training in the region has advanced in some countries to the point that there is specialization in adolescent medicine, much remains to be done. Certain regional conditions have contributed to the education of providers in adolescent care. The most important has been the existence of professionals who have been highly motivated to improve the health of young people. They have worked very hard and with great commitment to achieve this goal. There have also been important obstacles to educating professionals in adolescent care. Aside from the usual lack of funding, barriers have existed in the health care system and its providers, as well as the training entities and because of certain South American conditions. Finally, this article describes the regional adolescent medicine programs and the status of recognition of this specialty, and addresses the opportunities and challenges for adolescent health training.

  19. Accessibility of adolescent health services

    Directory of Open Access Journals (Sweden)

    S Richter

    2000-09-01

    Full Text Available Adolescents represent a large proportion of the population. As they mature and become sexually active, they face more serious health risks. Most face these risks with too little factual information, too little guidance about sexual responsibility and multiple barriers to accessing health care. A typical descriptive and explanatory design was used to determine what the characteristics of an accessible adolescent health service should be. Important results and conclusions that were reached indicate that the adolescent want a medical doctor and a registered nurse to be part of the health team treating them and they want to be served in the language of their choice. Family planning, treatment of sexually transmitted diseases and psychiatric services for the prevention of suicide are services that should be included in an adolescent accessible health service. The provision of health education concerning sexual transmitted diseases and AIDS is a necessity. The service should be available thought out the week (included Saturdays and within easy reach. It is recommended that minor changes in existing services be made, that will contribute towards making a health delivery service an adolescent accessible service. An adolescent accessible health service can in turn make a real contribution to the community’s efforts to improve the health of its adolescents and can prove to be a rewarding professional experience to the health worker.

  20. Grosor de la íntima-media de la arteria carótida en adolescentes obesos y su relación con el síndrome metabólico Intima-media thickness in obese adolescents and their relation with metabolic syndrome

    Directory of Open Access Journals (Sweden)

    C. Torrejón

    2012-02-01

    Full Text Available Introducción: Los adolescentes obesos presentan mayor riesgo cardiovascular (RCV. La medición del grosor de la intima-media (GIM arterial detecta tempranamente el compromiso vascular. Objetivo: Evaluar si los adolescentes obesos tienen mayor compromiso vascular medido por GIM que los adolescentes no obesos, y si este es mayor en aquellos con síndrome metabólico (SM. Metodología: Grupo estudio (GE, niños obesos, IMC/edad > p95, con y sin SM y grupo control, IMC/edad p10-85, sin patología nutricional ni endocrina. Se midieron concentraciones séricas de lípidos, prueba tolerancia oral a glucosa con insulinemia y ecografía de arteria carótida. Para evaluar diferencia entre grupos se utilizaron pruebas estadísticas paramétricas y no paramétricas. Resultados: Se evaluaron 45 adolescentes obesos (20 mujeres, 19 con SM, edad 13 (9-16 años y 18 controles (14 mujeres, edad 13 (11-16 años. GIM del bulbo carotideo y de la arteria carótida interna (ACI fueron significativamente mayores en GE que grupo control (0,54 vs 0,34; 0,34 vs 0,25, p Introduction: Obese adolescents have higher cardiovascular risk (CVR. Intima-media thickness (IMT detects early arterial vascular compromise. Objective: To evaluate whether obese adolescents have higher vascular compromise measured by IMT than nonobese adolescents, and if this is greater in those with metabolic syndrome (MS. Method: The study group (SG, obese children (BMI/age > p95, with and without MS and control group (CG, non-obese (BMI/age p10-85 and non nutritional or endocrine disease. We measured serum lipids, oral glucose tolerance test with insulin and carotid artery ultrasound. To evaluate the differences between test groups we used parametric and nonparametric statistics. Results: We evaluated 45 obese adolescents (20 women, 19 with MS, age 13 (9-16 years and 18 controls (14 women, aged 13 (11-16 years. IMT of carotid bulb and internal carotid artery (ICA were significantly higher in SG than CG

  1. Reabilitação psicológica de pacientes com seqüelas da encefalite por arbovirus Psychological rehabilitation of patients with sequelae due to encephalitis caused by arbovirus

    Directory of Open Access Journals (Sweden)

    Anency Giannotti Hallage

    1981-10-01

    Full Text Available Foi investigado o possível comprometimento psíquico de pacientes com seqüelas da encefalite por arbovirus, do litoral sul do Estado de São Paulo (Brasil, com a finalidade de definir o papel do psicólogo, em um programa de reabilitação física e psicossocial. A presença das seqüelas era encarada de forma depreciativa e observou-se que essa percepção comprometeu fundamentalmente a identidade do paciente como ser humano, trazendo uma série de respostas emocionais desadaptadas e impossibibilitando a convivência satisfatória consigo e com o próximo. Os resultados analisados, em seu aspecto psicossociológico, revelaram que as dificuldades psíquicas observadas eram originárias da maneira como a deficiência física é encarada no meio social.The possibility of psychological damage in patients with sequelae from encephalitis caused by arbovirus in the southern section of the coastal area of the State of S. Paulo (Brazil was investigated for the purpose of defining the role of the psychologist in a programme of physical and psychosocial rehabilitation. The presence of the sequelae was regarded depreciatively by the patients and this attitude affected their self-regard as human beings. The result was a series of emotional maladjustments which made it impossible for the patients to live with themselves or maintain a satisfactory relationship with others. The results analyzed from a psychosocial standpoint revealed that the psychological problems observed arose from the way in which the physical deficiency is regarded within the social context.

  2. 颅骶技术用于脑外伤后遗症康复治疗%Craniosacral technique used in the treatment of brain trauma sequela rehabilitation: a personalized scheme

    Institute of Scientific and Technical Information of China (English)

    狄荣科; 曾建; 卜浪; 谭文捷

    2012-01-01

    Objective To use craniosacral technology for brain trauma sequela, to discuss the curative effect of personalized scheme of craniosacral therapy and its feasibility. Methods One patient with brain trauma sequela more than ten years was treated with comprehensive treatment plan of the craniosacral therapy. Conditions of Zang and Fu visceral organs and Meridian function were evaluated by meridian detector respectively before and after treatment. Results After treatment, Zang and Fu visceral organs and meridian function of the patient were improved obviously, self-conscious symptom was disappeared (all P < 0.05). Conclusion Craniosacral therapy has the obvious stimulative effect for the rehabilitation after traumatic brain injury by adjusting the integrated function of Zang and Fu visceral organs and Meridians.%目的 应用颅骶技术治疗脑外伤后遗症,探讨颅骶疗法个性化方案的疗效及其可行性.方法 选取脑外伤后遗症患者1例,采用颅骶疗法综合治疗方案,分别于治疗前和治疗后用经络检测仪评价脏腑和经络功能状态.结果 治疗后患者在脏腑和经络功能均有明显改善,自觉症状消失,差异均有统计学意义(均P < 0.05).结论 颅骶疗法通过调节脏腑和经络的整体功能,对脑外伤后遗留的身心损伤的康复具有明显的促进作用.

  3. Contraceptive needs of the adolescent.

    Science.gov (United States)

    Steyn, Petrus S; Goldstuck, Norman D

    2014-08-01

    The provision of contraception to adolescents requires specific attention. Adolescents require contraceptive methods which are safe, effective and simple to use. While long-acting reversible contraceptive methods are preferable, they should have a choice and not be forced or mandated especially in situations where this may compromise safety. After counselling they should have the ability to choose any method of contraception. Under the appropriate circumstances, each method of contraception may have a place. This chapter will be devoted to evaluating the most current scientific rationale for the indication for use of each method of contraception in adolescents.

  4. The role of parental and adolescent attributions in adjustment of adolescents with chronic illness.

    Science.gov (United States)

    Guion, Kimberly; Mrug, Sylvie

    2012-09-01

    Previous literature has demonstrated the separate contributions of parental attributions and adolescent attributions to psychosocial adjustment of adolescents with chronic illness. However, it is unknown whether parental attributions affect adolescents' mental health directly or indirectly by influencing the youths' attributional style. This study evaluated the direct and indirect (through adolescent attributions) effects of parental attributions on internalizing and externalizing problems of adolescents with chronic illness. Adolescents (N = 128; M = 14.7 years) diagnosed with cystic fibrosis or diabetes and their caregivers completed measures of attributional style and adolescent adjustment. Parents' optimistic attributions were associated with fewer adolescent internalizing and externalizing problems. These effects were partly mediated by adolescent attributions. These results suggest that targeting both adolescent and parent attributions may be important for improving adolescents' adjustment to a chronic illness.

  5. Asthma in adolescent athletes.

    Science.gov (United States)

    Carlsen, Kai-Håkon; Hem, Erlend; Stensrud, Trine

    2011-12-01

    Athletes active in endurance sports are at an increased risk of acquiring asthma through their sports activities, especially so for cross-country skiers, biathlon skiers, swimmers and athletes of other endurance sports. Asthma may be present from early childhood or develop while in active sports. This article focuses on the physical activity and sports activities in children and adolescents. Exercise-induced asthma (EIA) is found in 8-10% of a normal child population of school age and in about 35% of children with current asthma. EIA is caused by the markedly increased ventilation during exercise, with increased heat and water loss through respiration, leading to bronchial constriction. The risk of developing asthma in the young athlete is related to the repeated daily training activity with increased epithelial damage of the airways, delayed repair due to the daily repetition of the training and increased airway mucosal inflammation. The increased environmental exposure through the sports activity to environmental agents, such as cold, dry air in skiers and chlorine compounds in swimmers, increases symptoms and signs of asthma and bronchial hyper-responsiveness, either worsening an existing asthma or leading to a novel disease in a previously healthy athlete. Several specific aspects of daily training life, environmental exposure, diagnostic procedures and aspects of treatment related to the regulations of medication use in sports need particular attention when addressing the adolescent athlete with respiratory symptoms.

  6. Smoking and adolescent health

    Directory of Open Access Journals (Sweden)

    Sang-hee Park

    2011-10-01

    Full Text Available With the Westernization and opening of our society, adolescents’ smoking is increasing and being popularized. Many adolescents start smoking at an early age out of curiosity and venturesomeness, and earlier start of smoking makes it more difficult to quit smoking. Adolescents’ habitual smoking not only becomes a gateway to all kinds of substance abuse but also causes various health problems including upper respiratory infection, immature lung development, reduced maximum vital capacity, and lung cancer. Therefore, it is quite important to prevent adolescents from smoking. The lowering of adolescents’ smoking rate cannot be achieved only through social restrictions such as stereotyped education on the harms of smoking and ID checking. In order to lower adolescents’ smoking rate substantially, each area of society should develop standardized programs and make related efforts. As adolescents’ smoking is highly influenced by home environment or school life, it is necessary to make efforts in effective education and social reinforcement in school, to establish related norms, and to execute preventive education using peer groups. When these efforts are spread throughout society in cooperation with homes and communities, they will be helpful to protect adolescents’ health and improve their quality of life.

  7. Evidence of mitochondrial dysfunction in obese adolescents

    DEFF Research Database (Denmark)

    Wilms, L; Larsen, J; Pedersen, P L

    2010-01-01

    and elucidate whether a lower metabolic rate is present. Methods: In a group of 34 obese adolescents (age adolescent, thyroid stimulating hormone (TSH) and basal oxygen consumption were measured...... and mitochondrial function in peripheral blood monocytes was determined by flow cytometry. Results: Significant increase in TSH (3.06 +/- 1.56 mU/L vs. 2.33 +/- 0.91 mU/L, p adolescents...... compared with lean adolescents. Flow cytometry analysis demonstrated a lower mitochondrial mass (6385 +/- 1962 a.u. vs. 7608 +/- 2328 a.u., p adolescents compared with lean adolescents...

  8. Gender and Competition in Adolescence

    DEFF Research Database (Denmark)

    Dreber, Anna; Essen, Emma von; Ranehill, Eva

    2013-01-01

    We look at gender differences among adolescents in Sweden in preferences for competition, altruism and risk. For competitiveness, we explore two different tasks that differ in associated stereotypes. We find no gender difference in competitiveness when comparing performance under competition...

  9. Self-Injury in Adolescents

    Science.gov (United States)

    ... symptom that results from a variety of factors. Adolescents who have difficulty talking about their feelings may show their emotional tension, physical discomfort, pain and low self-esteem with self-injurious behaviors. Although some teenagers may ...

  10. Adolescent Relationship Abuse (ARA) Toolkit

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Adolescent Relationship Abuse (ARA) Toolkit provides information and strategies on how to: incorporate abuse prevention into programming; conduct staff training;...

  11. among orthodontically untreated Nigerian adolescents

    African Journals Online (AJOL)

    Although considerable proportion of the adolescents perceived .... premolars teeth in the maxillary and mandibular arches) 6. 2. ... Anterior maxillary ovc-Jjet in millimetre 2 ... Antero-posterior molar relation, largest deviation from normal.

  12. Online Communication and Adolescent Relationships

    National Research Council Canada - National Science Library

    Kaveri Subrahmanyam; Patricia Greenfield

    2008-01-01

    .... As a group, adolescents are heavy users of newer electronic communication forms such as instant messaging, e-mail, and text messaging, as well as communication-oriented Internet sites such as blogs...

  13. Measuring risky adolescent cycling behaviour.

    Science.gov (United States)

    Feenstra, Hans; Ruiter, Robert A C; Schepers, Jan; Peters, Gjalt-Jorn; Kok, Gerjo

    2011-09-01

    Adolescents are at a greater risk of being involved in traffic accidents than most other age groups, even before they start driving cars. This article aims to determine the factor structure of a self-report questionnaire measuring adolescent risky cycling behaviour, the ACBQ (Adolescent Cycling Behaviour Questionnaire). The questionnaire's structure was based on the widely used Driver Behaviour Questionnaire (DBQ). A sample of secondary school students (N = 1749; age range: 13-18 years) filled out the questionnaire. Factor analysis revealed a three-factor structure underlying the questionnaire, which was confirmed on two equally large portions of the entire sample. These three underlying factors were identified as errors, common violations and exceptional violations. The ACBQ is a useful instrument for measuring adolescents' risky cycling behaviour.

  14. POLYCYSTIC OVARY SYNDROME IN ADOLESCENCE

    Directory of Open Access Journals (Sweden)

    Diana Baptista

    2017-02-01

    Conclusion: Identification of adolescents at risk for Polycystic Ovary Syndrome is critical, not only for an appropriate therapeutic approach, but also to prevent co-morbidities associated with the syndrome, including obesity, insulin resistance, dyslipidemia and infertility.

  15. Developmental hip dysplasia in adolescence

    Directory of Open Access Journals (Sweden)

    Vukašinović Zoran

    2009-01-01

    Full Text Available The authors define adolescence and developmental dysplasia of the hip (DDH. Special attention is paid to pathological findings characteristic of DDH in adolescence (unrecognized and untreated DDH; treated DDH, but non-terminated treatment; DDH diagnosed with delay, inadequately treated, with complications. The authors emphasise that DDH treatment has to be successfully terminated well before the adolescence; possibilities are explained on management modes at the time of adolescence, and possible persons guilty for the persistence of later hip problems are indicated. Based on the authors' experience and having in mind all surgical possibilities for the treatment (pelvic osteotomies, femoral osteotomies, trochanteroplasties, leg length equalization procedures the authors propose treatment protocols. The intention is to provide better treatment results and to prevent secondary hip arthrosis. Furthermore, how to improve the struggle against DDH is suggested.

  16. Factors contributing to adolescent obesity.

    Science.gov (United States)

    Al-Kloub, Manal I; Froelicher, Erika S

    2009-06-01

    Obesity in children is a significant public health concern. The prevalence of overweight and obesity in Jordanian children, and adolescents has increased in the last decade. The consequences of obesity to health in childhood and adulthood have both medical, and economic cost to individuals and society. This paper reviews the factors that contribute to adolescent obesity and emphasizes behavioral and environmental factors. An individual's behaviors such as increased consumption of high caloric foods, increased sedentary activity while decreasing physical activity has been identified as key issues in the development of obesity. Additionally, the current environment in homes, schools, and neighborhoods tend to discourage a healthy lifestyle. A comprehensive approach that involves the whole community is the best strategy for preventing adolescent obesity. Nurses are in a unique position to provide leadership in developing programs for healthier lifestyle choices for adolescents' and adoption of these goals into their daily lives.

  17. Fear, Fiction, and the Adolescent.

    Science.gov (United States)

    Grixti, Joe

    1982-01-01

    The popularity of horror fiction among adolescents is discussed in terms of the use of grammar for social interaction, personal development, and emotional therapy during a developmental stage characterized by fear and emotional upheaval. (MSE)

  18. Contraceptive care for the adolescent.

    Science.gov (United States)

    Feldman, Elizabeth

    2006-06-01

    Despite recent improvements in rates of teen pregnancy, abortion, birth,and contraceptive use, effective contraceptive counseling for adolescents should be a high priority for the primary care provider in the office setting. Adolescent psychosocial risk screening and appropriate counseling about sexual decision-making is necessary. Contraceptive services visits include, relevant history, limited physical examination, provision of information, anticipatory guidance about sexual behaviors, and the provision of contraceptive methods. Teens should always be encouraged to use a male condom during sex to reduce STI risk. A variety of barrier and hormonal contraceptive methods are available for the adolescent population. Education about and provision of EC is effective in reducing the rate of unintended pregnancy and abortion in the United States. Contraceptive care for adolescents is a rewarding experience for primary care providers.

  19. PREGNANCY AND DELIVERY OF ADOLESCENTS

    Directory of Open Access Journals (Sweden)

    Janka Palancsai Šiftar

    2003-12-01

    Full Text Available Background. Adolescence is the period between childhood and adulthood. In adolescence a higher incidence of complications in pregnancy and during labour is noted, especially a higher number of preeclampsia, anemia, preterm labours, very low birth-weight infants and/or too small for gestational age infants. However, where antenatal care has been given more attention, the number of the above mentioned complications in the course of pregnancy and labour has in adolescents not been so high.In the region of Pomurje there is a lot of primiparous adolescents under twenty years of age in comparison to other regions of Slovenia. In the present work I have investigated the complications in pregnancy, during labour, with newborns and the characterictics of antenatal care for adolescents.Methods. The analysis is based on the data taken from the Perinatal Informational System of Slovenia for the six years (1987–1992. The register is uniform for the total teritory of Slovenia since 1986. The data collected are the data about the pregnancy and delivery, about post-delivery period and about the newborn. In the study group the primiparous adolescents, aged up to 19 years were included. The control group consisted of primiparas in the age group 20–34 years.Results. The study included 3553 primiparas. There were 786 (22.1% primiparus adolescents in the study group; and 2767 (77.9% women aged 20–34 years in the control group. The results show that the number of labours decreased in both the study and the control group. Adolescents care less for antenatal examinations, a higher percentage of them is single and have accomplished fewer years of education. In pregnancy the incidence of anemia is higher, and the percent of intrauterine growth retardation is significantly higher in the control group. In the studygroup the onset of labour is more often spontaneous with contractions, and the number of preterm labours is higher too. Birth weight of newborns of

  20. Brain tumors in children and adolescents: cognitive and psychological disorders at different ages.

    Science.gov (United States)

    Poggi, Geraldina; Liscio, Mariarosaria; Galbiati, Susanna; Adduci, Annarita; Massimino, Maura; Gandola, Lorenza; Spreafico, Filippo; Clerici, Carlo Alfredo; Fossati-Bellani, Franca; Sommovigo, Michela; Castelli, Enrico

    2005-05-01

    Cognitive and psychological disorders are among the most frequently observed sequelae in brain tumor survivors. The goal of this work was to verify the presence of these disorders in a group of children and adolescents diagnosed with brain tumor before age 18 years, differentiate these disorders according to age of assessment, identify correlations between the two types of impairments and define possible associations between these impairments and clinical variables. The study involved 76 patients diagnosed with brain tumor before age 18 years. Three age groups were formed, and all the patients received a standardized battery of age-matched cognitive and psychological tests. According to our findings, all three groups present with cognitive and psychological-behavioral disorders. Their frequency varies according to age of onset and is strongly associated to time since diagnosis. The performance intelligence quotient (PIQ) was more impaired than the verbal intelligence quotient (VIQ). Internalizing problems, withdrawal and social problems were the most frequent psychological disorders. Correlations were found between cognitive impairment and the onset of the main psychological and behavioral disorders. These findings are relevant as they point out the long-term outcome of brain tumor survivors. Hence, the recommendation to diversify psychological interventions and rehabilitation plans according to the patients' age.